PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2606106-5	1989	From the obtained results, it appears that the two glycans of Tf 5b variant are, like in human serotransferrin, of the N-acetyllactosaminic biantennary type, fully sialylated by two residues of N-acetylneuraminic acid (Neu5Ac; glycan type I).	Nitrogen	119-120	transferrin	Homo sapiens	95-110
2619923-8	1989	After prior treatment with sialidase, both plasma and amniotic fluid fibronectins strongly reacted with erythrocyte phytohaemagglutinin (E-PHA), indicating that both fibronectin isoforms contain bisecting (beta 1-4) N-acetylglucosamine residues.	Nitrogen	216-217	fibronectin 1	Homo sapiens	69-80
2513184-5	1989	Inhibition of N-linked glycosylation by treatment with tunicamycin, 2-deoxy-D-glucose or glucosamine stimulated the synthesis of non-ADP-ribosylated GRP78 up to sixfold with relatively little effect on its ADP-ribosylation.	Nitrogen	14-15	heat shock protein 5	Mus musculus	149-154
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Nitrogen	0-1	tripartite motif containing 47	Homo sapiens	42-45
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Nitrogen	0-1	tripartite motif containing 47	Homo sapiens	84-87
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Nitrogen	0-1	tripartite motif containing 47	Homo sapiens	84-87
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Nitrogen	0-1	tripartite motif containing 47	Homo sapiens	84-87
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Nitrogen	36-37	tripartite motif containing 47	Homo sapiens	42-45
2698147-10	1989	This has resulted in circulating IGF I and II determinations becoming useful diagnostic markers of endocrine-based growth disorder and nitrogen balance.	Nitrogen	135-143	insulin like growth factor 1	Homo sapiens	33-38
2626743-8	1989	Knowing the amino acid composition and the relative proportions of these fractions, the nitrogen contents of the clots were converted to fibrinogen.	Nitrogen	88-96	fibrinogen beta chain	Homo sapiens	137-147
2816803-6	1989	Changes in IGF-1 were correlated with nitrogen balance (r = 0.45, p less than 0.005).	Nitrogen	38-46	insulin like growth factor 1	Homo sapiens	11-16
2816803-7	1989	The strong relationship between IGF-1 and nutritional status suggests that IGF-1 determinations may be useful in guiding nutritional therapy in patients whose nitrogen balance is difficult to assess.	Nitrogen	159-167	insulin like growth factor 1	Homo sapiens	75-80
2605196-3	1989	The compound (5,5,5-trifluoro-4-oxopentyl)trimethylammonium bicarbonate (1) inhibits acetylcholinesterase with Ki = 0.06 X 10(-9)M and pseudocholinesterase with Ki = 70 X 10(-9)M. Replacement of the nitrogen of 1 by carbon (compound 2) increases Ki for 1 200-fold for acetylcholinesterase but does not significantly alter Ki for pseudocholinesterase.	Nitrogen	199-207	acetylcholinesterase (Cartwright blood group)	Homo sapiens	85-105
2614424-0	1989	The effect of ginsenoside-Rb2 on nitrogen balance.	Nitrogen	33-41	RB transcriptional corepressor like 2	Rattus norvegicus	26-29
2614424-2	1989	Ginsenoside-Rb2 was found to suppress the total urinary excretion of nitrogen, increase nitrogen retention in the body, and thereby improve nitrogen balance.	Nitrogen	69-77	RB transcriptional corepressor like 2	Rattus norvegicus	12-15
2614424-2	1989	Ginsenoside-Rb2 was found to suppress the total urinary excretion of nitrogen, increase nitrogen retention in the body, and thereby improve nitrogen balance.	Nitrogen	88-96	RB transcriptional corepressor like 2	Rattus norvegicus	12-15
2614424-2	1989	Ginsenoside-Rb2 was found to suppress the total urinary excretion of nitrogen, increase nitrogen retention in the body, and thereby improve nitrogen balance.	Nitrogen	88-96	RB transcriptional corepressor like 2	Rattus norvegicus	12-15
2516221-7	1989	A decrease of P/N ratio was also observed in the early phase after administration of erythropoietin, an agent which induces differentiation and multiplication of erythroblasts.	Nitrogen	16-17	erythropoietin	Homo sapiens	85-99
2516221-9	1989	However, following the initial decrease, the P/N ratio increased gradually 48 h after administration of erythropoietin.	Nitrogen	47-48	erythropoietin	Homo sapiens	104-118
2559540-3	1989	The ORF1 has the potential to code for a protein of 501 amino acids with a molecular weight of 56 kD that contains strong hydrophobic regions in both the amino and carboxyl termini, and nine potential N-linked glycosylation sites, while the ORF2 is capable of coding for a 24-kD protein.	Nitrogen	201-202	ORF1	Homo sapiens	4-8
2618083-4	1989	Spectral interactions of N-containing heteroaromatic compounds with the cytochrome P-450 system are type I or type II depending on the state of induction, and are relatively weak.	Nitrogen	25-26	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	72-88
2478047-5	1989	From a detailed examination of structure-activity relationships, the authors conclude that the important structural features of the morphine allergenic (that is, IgE binding) determinant comprises the cyclohexenyl ring with a hydroxyl group at C-6 and, most important of all, a methyl substituent attached to the N atom.	Nitrogen	313-314	immunoglobulin heavy constant epsilon	Homo sapiens	162-165
2789018-3	1989	Pulse-chase experiments reveal that newly synthesized IL-6 polypeptides rapidly enter two separate protein modification pathways: one leads to O-glycosylation and the other to both N- and O-glycosylation; polypeptides in both pathways are further modified (phosphorylation) prior to secretion.	Nitrogen	181-182	interleukin 6	Homo sapiens	54-58
2789018-5	1989	In the presence of tunicamycin, IL-6 is secreted exclusively in the O-glycosylated form, whereas in the presence of cycloheximide the pathway leading to both N- and O-glycosylation is dominant.	Nitrogen	158-159	interleukin 6	Homo sapiens	32-36
2811858-7	1989	From the enhanced ferrochelatase-inhibitory potency of the NB plus NA regioisomers of N-ethylPP and the NB/A regioisomer(s) of N-propylPP that were isolated from rat liver, relative to the corresponding synthetic N-alkyllPP regioisomers, it was inferred that 2- and 4-vinyl substituents located on pyrrole rings A and B contribute to the optimal binding of N-alkylPPs to the ferrochelatase active site.	Nitrogen	59-60	ferrochelatase	Rattus norvegicus	18-32
2813359-7	1989	These results suggest that higher branching of the N-linked sugar chains is essential for effective expression of in vivo biological activity of EPO.	Nitrogen	51-52	erythropoietin	Homo sapiens	145-148
2514791-2	1989	The t-PA polypeptide has four potential N-glycosylation sites of which three are occupied in type I (Asn-117, -184, and -448) and two in type II (Asn-117 and -448).	Nitrogen	40-41	plasminogen activator, tissue type	Homo sapiens	4-8
2802836-6	1989	Kinetic studies demonstrated that the anabolic effects of GH were associated with increased protein synthesis, and amino acid flux studies across the forearm revealed increased uptake of amino acid nitrogen in the GH-treated patients.	Nitrogen	198-206	growth hormone 1	Homo sapiens	214-216
2514793-4	1989	Further, both rt-PA"s are N-glycosylated differently from t-PA derived from a human colon fibroblast and the Bowes melanoma cell line (Parekh et al., 1989), confirming that N-glycosylation of the human t-PA polypeptide is cell-type-specific.	Nitrogen	26-27	plasminogen activator, tissue type	Homo sapiens	15-19
2514793-4	1989	Further, both rt-PA"s are N-glycosylated differently from t-PA derived from a human colon fibroblast and the Bowes melanoma cell line (Parekh et al., 1989), confirming that N-glycosylation of the human t-PA polypeptide is cell-type-specific.	Nitrogen	173-174	plasminogen activator, tissue type	Homo sapiens	15-19
2789217-5	1989	Rat IL6 lacks N-glycosylation sites but contains a fifth cysteinyl residue in addition to the 4 residues shared in conserved positions with murine and human IL6.	Nitrogen	14-15	interleukin 6	Rattus norvegicus	4-7
2514791-3	1989	In an effort to elucidate the factors controlling the expression of N-linked oligosaccharides on this polypeptide, we have used a combination of sequential exoglycosidase digestion, methylation analysis, and controlled acetolysis to determine the oligosaccharide structures at each of the N-glycosylation sites of type I and type II t-PA when isolated from a human colon fibroblast cell strain and from a Bowes melanoma cell line.	Nitrogen	68-69	plasminogen activator, tissue type	Homo sapiens	333-337
2590174-6	1989	Thermospray liquid chromatography-mass spectrometry showed the C-terminal N-glycosylation site to be largely unmodified, and also showed that the N-terminus of the purified recombinant IL-4 (rIL-4) was authentic.	Nitrogen	74-75	interleukin 4	Homo sapiens	185-189
2514792-1	1989	Tissue-type plasminogen activator (t-PA), when isolated from human colon fibroblast (hcf) cells, is N-glycosylated differently than when isolated from the Bowes melanoma (m) cell line (Parekh et al., 1988).	Nitrogen	100-101	plasminogen activator, tissue type	Homo sapiens	0-33
2514793-1	1989	To probe the effects of N-glycosylation on the fibrin-dependent plasminogenolytic activity of tissue-type plasminogen activator (t-PA), we have expressed a human recombinant t-PA (rt-PA) gene in Chinese hamster ovary (CHO) cells and in a murine C127 cell line.	Nitrogen	24-25	plasminogen activator, tissue type	Homo sapiens	94-127
2514793-1	1989	To probe the effects of N-glycosylation on the fibrin-dependent plasminogenolytic activity of tissue-type plasminogen activator (t-PA), we have expressed a human recombinant t-PA (rt-PA) gene in Chinese hamster ovary (CHO) cells and in a murine C127 cell line.	Nitrogen	24-25	plasminogen activator, tissue type	Homo sapiens	129-133
16666984-8	1989	We suggest that some of the ChiA protein is N-glycosylated and secreted when expressed in plants, and that the modifications are complex glycans.	Nitrogen	44-45	endochitinase A	Nicotiana tabacum	28-32
2551729-7	1989	The 30 kDa N-tryptic fragment (residues 4-281) and the re-associated N,C-tryptic complex bind to lactotansferrin lymphocyte receptor with a dissociation constant of 44 nM and 39 nM, respectively, similar to the value obtained for the native lactotransferrin (Kd = 46 nM).	Nitrogen	11-12	lactotransferrin	Homo sapiens	241-257
2673694-7	1989	Glucagon, alpha-amino acid nitrogen, and lactate concentrations were exquisitely sensitive to a rise in glucose and insulin concentrations.	Nitrogen	27-35	insulin	Homo sapiens	116-123
2788137-1	1989	Continuous infusion of murine recombinant interleukin-1 alpha (rIL-1 alpha) into rats by using intraperitoneally implanted osmotic pumps led to marked decreases in body weight, liver enzymes (serum glutamic oxalacetic transaminase, serum glutamic pyruvic transaminase, and sorbitol dehydrogenase), appetite, and mobility and increases in drinking, blood urea nitrogen, and total peripheral blood leukocytes within 3 days.	Nitrogen	359-367	interleukin 1 alpha	Rattus norvegicus	63-74
2491659-0	1989	Regulation of plant genes specifically induced in nitrogen-fixing nodules: role of cis-acting elements and trans-acting factors in leghemoglobin gene expression.	Nitrogen	50-58	leghemoglobin A	Glycine max	131-144
2761411-10	1989	Because ApoE was affected, both in the fed state and during refeeding by the form of dietary nitrogen, it may prove to reflect nitrogen balance and/or insulin: glucagon balance.	Nitrogen	93-101	apolipoprotein E	Rattus norvegicus	8-12
2677363-5	1989	However, because of the additional nitrogen atom in the triazole ring and the lipophilic tail, terconazole establishes a firmer and longer-lasting link with the membrane-bound fungal cytochrome P-450.	Nitrogen	35-43	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	183-199
2677666-6	1989	The AG alpha 1 gene could encode a 650-amino-acid protein with a putative signal sequence, 12 possible N-glycosylation sites, and a high proportion of serine and threonine residues, all of which are features expected for the alpha-agglutinin sequence.	Nitrogen	103-104	Sag1p	Saccharomyces cerevisiae S288C	4-14
2761411-10	1989	Because ApoE was affected, both in the fed state and during refeeding by the form of dietary nitrogen, it may prove to reflect nitrogen balance and/or insulin: glucagon balance.	Nitrogen	127-135	apolipoprotein E	Rattus norvegicus	8-12
2775751-9	1989	The active site histidine, His-186, is hydrogen bonded from nitrogen ND1 to the carboxylate of Asp-158 and from its nitrogen NE2 to the sulfate ion bound in the putative substrate binding site.	Nitrogen	60-68	NADH dehydrogenase subunit 1	Sus scrofa	69-72
2775751-9	1989	The active site histidine, His-186, is hydrogen bonded from nitrogen ND1 to the carboxylate of Asp-158 and from its nitrogen NE2 to the sulfate ion bound in the putative substrate binding site.	Nitrogen	116-124	NADH dehydrogenase subunit 1	Sus scrofa	69-72
2500299-8	1989	Patients who received the low NPC/N had significantly greater N retention (p less than .05), increased plasma transferrin levels (p less than .05), and a lower RQ (p less than .05).	Nitrogen	30-31	transferrin	Homo sapiens	110-121
2767786-0	1989	The post: pre-dialysis plasma urea nitrogen ratio to estimate K.t/V and NPCR: mathematical modeling.	Nitrogen	35-43	nasopharyngeal carcinoma-related protein	Homo sapiens	72-76
2486234-0	1989	The post: pre dialysis plasma urea nitrogen ratio to estimate K.t/V and NPCR: validation.	Nitrogen	35-43	nasopharyngeal carcinoma-related protein	Homo sapiens	72-76
2660586-1	1989	Rats treated with recombinant human tumor necrosis factor-cachectin, 100 micrograms/kg ip twice daily for 5 consecutive days, had a 56% decrease in food intake, a 54% decrease in nitrogen balance, and a 23-g decrease in body weight gain vs. saline-treated controls.	Nitrogen	179-187	tumor necrosis factor	Rattus norvegicus	58-67
16666879-5	1989	When nitrate was supplied to N-starved, etiolated corn plants, nitrate reductase, and glyceraldehyde-3-phosphate dehydrogenase mRNA levels in leaves increased in parallel.	Nitrogen	29-30	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	Zea mays	86-126
2656154-10	1989	In rats and in humans nourished parenterally, provision of balanced amino acid solutions or of only the three BCAA cause similar improvements in nitrogen balance for several days.	Nitrogen	145-153	AT-rich interaction domain 4B	Homo sapiens	110-114
2570824-4	1989	The principal binding forces occur through contacts between acidic amino acids of calmodulin and the protonated side-chain nitrogen of the drugs as well as between a basic amino acid and the electronegative substituents of the aromatic rings.	Nitrogen	123-131	calmodulin 1	Homo sapiens	82-92
2498325-8	1989	Apolipoprotein E(Thr194----Asn,Gly196----Ser), which introduces a potential site for N-glycosylation at position 194, was secreted with a higher apparent molecular weight than native, O-glycosylated apoE.	Nitrogen	85-86	apolipoprotein E	Homo sapiens	0-16
2498325-9	1989	Studies with tunicamycin indicated that this apoE was N-glycosylated at Asn194.	Nitrogen	54-55	apolipoprotein E	Homo sapiens	45-49
2802993-8	1989	Requirements of intestinal absorbed nitrogen and its conversion into milk protein are dependant of dietary nitrogen solubility and metabolizable energy concentration, while they are favourably influenced by energy supply.	Nitrogen	36-44	casein beta	Bos taurus	69-81
2802993-8	1989	Requirements of intestinal absorbed nitrogen and its conversion into milk protein are dependant of dietary nitrogen solubility and metabolizable energy concentration, while they are favourably influenced by energy supply.	Nitrogen	107-115	casein beta	Bos taurus	69-81
2475311-8	1989	Agp-1 and Agp-2 contain five and six potential N-glycosylation sites, respectively.	Nitrogen	47-48	anti gp70 immune complex 2	Mus musculus	10-15
2787317-5	1989	alpha 1-PI in solutions containing phosphate buffer (control), 0.1 mM stearic acid (saturated fatty acid, 18:0), or 0.1 mM linoleic acid (polyunsaturated fatty acid, 18:2) was exposed to either N2 or NO2 (50 ppm for 4 h).	Nitrogen	194-196	serpin family A member 1	Homo sapiens	0-10
2785120-8	1989	Compatible with these data was the finding that more prolonged infusions of recombinant TNF/cachectin and the combination with IL 1 increased urinary nitrogen excretion.	Nitrogen	150-158	tumor necrosis factor	Rattus norvegicus	92-101
2496144-0	1989	A gamma methionine-310 to threonine substitution and consequent N-glycosylation at gamma asparagine-308 identified in a congenital dysfibrinogenemia associated with posttraumatic bleeding, fibrinogen Asahi.	Nitrogen	64-65	fibrinogen beta chain	Homo sapiens	134-144
2497466-2	1989	Growth hormone is capable of improving total body nitrogen balance, but its role in myofibrillar protein synthesis in humans is unknown.	Nitrogen	50-58	growth hormone 1	Homo sapiens	0-14
2523818-7	1989	A small part of IL-6 (27.5 kDa form) is in addition N-glycosylated.	Nitrogen	52-53	interleukin 6	Homo sapiens	16-20
2771871-2	1989	All compounds prolonged hexobarbital-induced sleeping time in a dose-dependent manner (doses 3.0 and 30.0 mg/kg, except nifedipine 0.3 and 3.0 mg/kg) and inhibited cytochrome P450-dependent N-demethylation of aminopyrine in vitro in rat liver microsomes.	Nitrogen	190-191	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	164-179
2764701-11	1989	The efficiency of protein synthesis in the amino acid N-pool were in HESZ 64%, HES 70%, NESZ 70% and NES 73%, resp.	Nitrogen	54-55	nestin	Bos taurus	88-91
2564848-3	1989	The glutamate dehydrogenase pathway played an important role in ammonia assimilation in ammonia-grown cells but was found to play a minor role relative to that of the glutamine synthetase/NADPH-glutamate synthase pathway in nitrogen-fixing cells when the intracellular NH4+ concentration and the low affinity of the enzyme for NH4+ were taken into account.	Nitrogen	224-232	ATN24_RS09110	Clostridium butyricum	167-187
2701940-8	1989	A putative asparagine-linked N-glycosylation site which was conserved in the chicken vitellogenin II and the Xenopus laevis vitellogenin A2 gene, at the beginning of exon 23, is also present in vitellogenin III.	Nitrogen	29-30	vitellogenin 2	Gallus gallus	85-100
2701940-8	1989	A putative asparagine-linked N-glycosylation site which was conserved in the chicken vitellogenin II and the Xenopus laevis vitellogenin A2 gene, at the beginning of exon 23, is also present in vitellogenin III.	Nitrogen	29-30	a1-a	Xenopus laevis	85-97
2918517-4	1989	It was found that the chemical oxidative dealkylation of N-masked NFLXs proceeded when anion-stabilizing groups (e.g., CN, COR, COOR) are present on the alpha carbon of the nitrogen atom.	Nitrogen	57-58	distribution of corticosterone in adrenal cortex cells	Mus musculus	123-126
2918517-4	1989	It was found that the chemical oxidative dealkylation of N-masked NFLXs proceeded when anion-stabilizing groups (e.g., CN, COR, COOR) are present on the alpha carbon of the nitrogen atom.	Nitrogen	173-181	distribution of corticosterone in adrenal cortex cells	Mus musculus	123-126
2645501-4	1989	Human growth hormone produced a decrease in urea nitrogen synthesis from 6.8 +/- 0.5 to 4.2 +/- 0.4 mg/kg.h; (P less than .01), while plasma urea nitrogen decreased from 13.1 +/- 0.8 to 7.4 +/- 0.8 mg/dL; (P less than .01).	Nitrogen	49-57	growth hormone 1	Homo sapiens	6-20
2917018-5	1989	HLo-7 is also much more active than HI-6 when used as a reactivator for electric eel AChE inhibited by some N-unsubstituted derivatives of tabun.	Nitrogen	108-109	acetylcholinesterase (Cartwright blood group)	Homo sapiens	85-89
2565975-5	1989	The results suggest that by appropriate N-acylation or N-aminomethylation it may be feasible to protect pyroglutamyl-containing peptides against cleavage by pyroglutamyl aminopeptidase and to obtain a release of the parent peptide in the organism, hence improving the delivery characteristics of such peptides.	Nitrogen	40-41	carboxypeptidase Q	Homo sapiens	170-184
2565975-5	1989	The results suggest that by appropriate N-acylation or N-aminomethylation it may be feasible to protect pyroglutamyl-containing peptides against cleavage by pyroglutamyl aminopeptidase and to obtain a release of the parent peptide in the organism, hence improving the delivery characteristics of such peptides.	Nitrogen	55-56	carboxypeptidase Q	Homo sapiens	170-184
2513708-0	1989	Bradykinin infusion in long term postoperative parenteral nutrition improves nitrogen balance and protein synthesis.	Nitrogen	77-85	kininogen 1	Homo sapiens	0-10
2541824-1	1989	Limited conformational constraints have been introduced in the sequence of the C-terminal fragment of the peptide neurotransmitter neurokinin A by N-methylation of individual peptide bonds, and the biological activities of the peptides thus obtained were evaluated in order to assess the effect of such conformational constraint on receptor selectivity.	Nitrogen	147-148	tachykinin precursor 1	Homo sapiens	131-143
2680407-0	1989	Induction of the alcohol-inducible form of cytochrome P-450 by nitrogen-containing heterocycles: effects on pyridine N-oxide production.	Nitrogen	63-71	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	43-59
2634609-0	1989	Effect of recombinant human growth hormone on urinary 15N-nitrogen balance in girls with Turner syndrome as compared to children with growth hormone deficiency.	Nitrogen	58-66	growth hormone 1	Homo sapiens	28-42
2535725-5	1989	Pulse-chase studies in EECC-infected cells demonstrated that processing of gp80 to gp70 was delayed and that this retardation of envelope glycoprotein processing could be simulated in 61E-infected cells by treatment with the glucosidase inhibitor N-methyldeoxynojirimycin, a compound that causes retention of oligosaccharides in the high-mannose form.	Nitrogen	247-248	interleukin 6 receptor	Homo sapiens	75-79
2563595-1	1989	The nitrogen regulatory (NtrC) protein of enteric bacteria, which binds to sites that have the properties of transcriptional enhancers, is known to activate transcription by a form of RNA polymerase that contains the NtrA protein (sigma 54) as sigma factor (referred to as sigma 54-holoenzyme).	Nitrogen	4-12	neuronal growth regulator 1	Homo sapiens	217-221
2910211-4	1989	TNF administration was associated with anorexia, fluid retention, acute phase responses, and negative nitrogen balance.	Nitrogen	102-110	tumor necrosis factor	Homo sapiens	0-3
3149611-5	1988	Three of four potential N-glycosylation acceptor sites as well as the active site of rat PAI-1 are identical to the human protein.	Nitrogen	24-25	serpin family E member 1	Rattus norvegicus	89-94
3409882-4	1988	H-FABP isolated from bovine heart begins with an N-acetylated valine residue, however, as derived from analysis of the tryptic, amino-terminal-blocked peptide and the molecular mass of the peptide obtained via secondary-ion mass spectrometry.	Nitrogen	49-50	fatty acid binding protein 3	Bos taurus	0-6
3178489-5	1988	Insulinlike growth factor 1 (IGF-1) production and plasma concentrations increased in group 2 in a fashion corresponding to the changes in nitrogen exchange, whereas septic patients exhibited no change in IGF-1 level.	Nitrogen	139-147	insulin like growth factor 1	Homo sapiens	0-27
3178489-5	1988	Insulinlike growth factor 1 (IGF-1) production and plasma concentrations increased in group 2 in a fashion corresponding to the changes in nitrogen exchange, whereas septic patients exhibited no change in IGF-1 level.	Nitrogen	139-147	insulin like growth factor 1	Homo sapiens	29-34
3233307-1	1988	We have measured the rates of isotope exchange at the nitrogen of the indole ring of Trp-63 of lysozyme and of L-tryptophan as a function of solution viscosity.	Nitrogen	54-62	lysozyme	Homo sapiens	95-103
2459385-2	1988	A fourth sequence, with an additional N-terminal 6-aminocaproyl residue on the substance P-hapten sequence, was cyclized N- to C-terminally.	Nitrogen	38-39	tachykinin precursor 1	Homo sapiens	79-90
2842153-8	1988	The N-3 nitrogen of this residue forms one of the axial ligands to the iron in the intact cytochrome c but it is uncoordinated in the iron-free derivative.	Nitrogen	8-16	cytochrome c, somatic	Homo sapiens	90-102
3182860-1	1988	The glycoprotein hormone erythropoietin (Ep), the primary regulator of erythropoiesis, is synthesized by the kidney and secreted as the mature protein with three N-linked and one O-linked oligosaccharide chains.	Nitrogen	162-163	erythropoietin	Homo sapiens	25-39
3148040-7	1988	Nitrogen balance was significantly correlated with somatomedin-C concentration (r = 0.53, p less than 0.01), cumulative caloric intake (r = 0.68, p less than 0.01), and cumulative nitrogen intake (r = 0.72, p less than 0.01).	Nitrogen	0-8	insulin like growth factor 1	Homo sapiens	51-64
3408492-7	1988	These data indicate that SAP-2 possesses N-linked complex or hybrid type oligosaccharide chains.	Nitrogen	41-42	ETS transcription factor ELK3	Homo sapiens	25-30
2899993-7	1988	During nutrient infusions, GH caused positive nitrogen balance (1.0 +/- 0.3 g/m2/day vs. -1.2 +/- 0.3 in controls, p less than 0.001) and increased protein synthesis (16.8 +/- 0.7 g N/m2/day vs. 13.9 +/- 0.8, p less than 0.01).	Nitrogen	46-54	growth hormone 1	Homo sapiens	27-29
2899993-14	1988	GH administration results in a hormonal-substrate environment that favors nitrogen retention and protein synthesis.	Nitrogen	74-82	growth hormone 1	Homo sapiens	0-2
3046674-3	1988	This discharge seems to result from activation of N-cholinoreceptors because non-noxious and nonalgogenic M-agonist Mch as well as Ach in subnoxious concentrations induce in SU only a low-frequency discharge with a mean frequency of impulses 0.5-3.5 Hz.	Nitrogen	50-51	pro-melanin concentrating hormone	Homo sapiens	116-119
3402460-4	1988	The occurrence of N-linked di-, tri- and tetraantennary glycans on these three molecular forms (AGP-A, -B, and -C) was studied by sequential lectin-affinity chromatography of the 14C-labelled glycopeptides.	Nitrogen	18-19	orosomucoid 1	Homo sapiens	96-101
16593965-3	1988	beta-1,3-Glucanase is produced as a 359-residue preproenzyme with an N-terminal hydrophobic signal peptide of 21 residues and a C-terminal extension of 22 residues containing a putative N-glycosylation site.	Nitrogen	69-70	glucan endo-1,3-beta-glucosidase, acidic-like	Nicotiana tabacum	0-18
2839618-9	1988	Mechanisms that involve potentiation of Ns-mediated effects are much more sensitive to calmodulin than is the activation of basal adenylate cyclase activity.	Nitrogen	40-42	calmodulin	Bos taurus	87-97
3393143-5	1988	These findings supported the idea that the ferrochelatase active site could accommodate alkyl groups larger than methyl only if they were present on the nitrogens of the A or B pyrrole rings of the N-alkylPP.	Nitrogen	153-162	ferrochelatase	Rattus norvegicus	43-57
3294337-1	1988	Treatment of rats with recombinant human TNF initially causes a marked decrease in food intake, a loss of body weight, and a negative nitrogen balance.	Nitrogen	134-142	tumor necrosis factor	Homo sapiens	41-44
3133995-1	1988	Recombinant human methionyl growth hormone (Protropin) (Genetech, Inc., San Francisco, CA) administered to normal volunteers receiving hypocaloric parenteral nutrition minimized weight loss and induced positive nitrogen balance.	Nitrogen	211-219	growth hormone 1	Homo sapiens	28-42
3133995-5	1988	Daily balance studies demonstrated that administration of GH resulted in significant retention of nitrogen (+3.4 g/24 h) and phosphorus (+218 mg/24 h), despite provision of only 60% of caloric requirements.	Nitrogen	98-106	growth hormone 1	Homo sapiens	58-60
3133995-6	1988	With GH, serum blood urea nitrogen (BUN) and potassium fell, whereas glucose and insulin tended to rise, and levels of insulin-like growth factor 1 increased three to fourfold.	Nitrogen	26-34	growth hormone 1	Homo sapiens	5-7
3133995-9	1988	Significant nitrogen and phosphorus retention occurred over the entire period of GH administration, and no significant side effects were observed.	Nitrogen	12-20	growth hormone 1	Homo sapiens	81-83
3133995-10	1988	In these depleted patients, GH caused significant and sustained nitrogen retention over a wide range of nutritional support.	Nitrogen	64-72	growth hormone 1	Homo sapiens	28-30
3220834-10	1988	N-Methylamide-modified gangliosides were resistant to hydrolysis by mouse hepatic sialidase, to elongation by glycosyltransferase and to N-glycolylation at N-acetylneuraminic acid by monooxygenase.	Nitrogen	0-1	protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2	Mus musculus	110-129
3288503-1	1988	One or both of two putative N-glycosylation sites (at asparagine-5 and -75) of human renin was eliminated by amino acid replacement of the asparagine residue with an alanine residue using site-directed mutagenesis.	Nitrogen	28-29	renin	Homo sapiens	85-90
3393628-6	1988	However, MSH was found to restore most of the protective effect of t-butanol under N2.	Nitrogen	83-85	msh homeobox 2	Homo sapiens	9-12
3393628-8	1988	The observed protection may be explained essentially in terms of (1) OH scavenging, (2) "repair" of DNA radicals by H-atom transfer from MSH under N2 in competition with fixation of damage under O2, and (3) protection against inactivation by secondary t-butanol radicals by H-atom transfer to these radicals.	Nitrogen	147-149	msh homeobox 2	Homo sapiens	137-140
16347651-1	1988	A more sensitive analytical method for NO(3) was developed based on the conversion of NO(3) to N(2)O by a denitrifier that could not reduce N(2)O further.	Nitrogen	39-40	NBL1, DAN family BMP antagonist	Homo sapiens	86-91
16347651-7	1988	The denitrifier method was also used to measure the atom% of N in NO(3).	Nitrogen	61-62	NBL1, DAN family BMP antagonist	Homo sapiens	66-71
16347651-8	1988	This method avoids the incomplete reduction and contamination of the NO(3) -N by the NH(4) and N(2) pools which can occur by the conventional method of NO(3) analysis.	Nitrogen	95-99	NBL1, DAN family BMP antagonist	Homo sapiens	69-74
16347651-8	1988	This method avoids the incomplete reduction and contamination of the NO(3) -N by the NH(4) and N(2) pools which can occur by the conventional method of NO(3) analysis.	Nitrogen	95-99	NBL1, DAN family BMP antagonist	Homo sapiens	152-157
3379915-8	1988	Only the B10.D2 (H-2d) mice developed proteinuria, hematuria, and elevated blood urea nitrogen.	Nitrogen	86-94	granzyme C	Mus musculus	9-12
3391999-7	1988	Treatment of lysophospholipase with peptide: N-glycosidase F gave degraded products, suggesting that this protein contain N-linked carbohydrate chains.	Nitrogen	45-46	asparaginase	Rattus norvegicus	13-30
2856515-0	1988	N-chlorination of phenytoin by myeloperoxidase to a reactive metabolite.	Nitrogen	0-1	myeloperoxidase	Homo sapiens	31-46
2452086-12	1988	The inhibition of N-glycosylation by tunicamycin abolished the effect of interleukin-6 on the secretion of alpha 2-macroglobulin, indicating a possible role of interleukin-6 on N-glycosylation.	Nitrogen	18-19	interleukin 6	Homo sapiens	73-86
2452086-12	1988	The inhibition of N-glycosylation by tunicamycin abolished the effect of interleukin-6 on the secretion of alpha 2-macroglobulin, indicating a possible role of interleukin-6 on N-glycosylation.	Nitrogen	18-19	interleukin 6	Homo sapiens	160-173
2452086-12	1988	The inhibition of N-glycosylation by tunicamycin abolished the effect of interleukin-6 on the secretion of alpha 2-macroglobulin, indicating a possible role of interleukin-6 on N-glycosylation.	Nitrogen	177-178	interleukin 6	Homo sapiens	73-86
2452086-12	1988	The inhibition of N-glycosylation by tunicamycin abolished the effect of interleukin-6 on the secretion of alpha 2-macroglobulin, indicating a possible role of interleukin-6 on N-glycosylation.	Nitrogen	177-178	interleukin 6	Homo sapiens	160-173
2894410-2	1988	Irreversible inhibition of GABA transaminase by microinjection of gamma-vinyl GABA (GVG) led to a decrease in aspartate, glutamate, and glutamine levels and an increase in the GABA level, such that the nitrogen pool remained constant.	Nitrogen	202-210	4-aminobutyrate aminotransferase	Rattus norvegicus	27-44
2967760-5	1988	The transmembrane orientation of the TcR chains and of CD 3 gamma and CD 3 delta can be directly inferred from their primary structure, based on the presence of concensus N-linked glycosylation sites N-terminal of their transmembrane domains.	Nitrogen	171-172	CD3 delta subunit of T-cell receptor complex	Homo sapiens	70-80
3292797-4	1988	However, when the same subjects were on artificial beta-cell-directed insulin therapy, they manifested a significant net positive nitrogen balance of over 2 g/day.	Nitrogen	130-138	insulin	Homo sapiens	70-77
3292797-7	1988	Thus when compared to conventional insulin treatment, artificial beta-cell-directed insulin therapy was associated with a 14% increase in the rate of protein synthesis and a decrease of 20% in urea nitrogen production, leading to a net positive nitrogen balance.	Nitrogen	198-206	insulin	Homo sapiens	84-91
3292797-7	1988	Thus when compared to conventional insulin treatment, artificial beta-cell-directed insulin therapy was associated with a 14% increase in the rate of protein synthesis and a decrease of 20% in urea nitrogen production, leading to a net positive nitrogen balance.	Nitrogen	245-253	insulin	Homo sapiens	84-91
3363309-9	1988	The coefficients for calculation of minimal tolerated ambient pressure for a given PN2 in the tissue can be deduced directly from the half-times for nitrogen.	Nitrogen	149-157	amyloid beta precursor protein	Homo sapiens	83-86
3414438-0	1988	Enzymatic N-methylation of calmodulin.	Nitrogen	10-11	calmodulin 1	Homo sapiens	27-37
2892826-0	1988	Regulation of nitrogen assimilation in Saccharomyces cerevisiae: roles of the URE2 and GLN3 genes.	Nitrogen	14-22	glutathione peroxidase	Saccharomyces cerevisiae S288C	78-82
3337804-7	1988	Similarly, phospholipase A2-induced hydrolysis of endogenous PS in intact RSCs was markedly enhanced when ATP-depleted, but not when fresh cells, were incubated under nitrogen for 3.5 h. Deoxygenated ATP-depleted RSCs markedly enhanced the rate of thrombin formation in the presence of purified coagulation factors Xa, Va, prothrombin and Ca2+.	Nitrogen	167-175	phospholipase A2 group IB	Homo sapiens	11-27
2447084-5	1988	Four potential N-glycosylation sites are identified, two of which are conserved in rat hepatic lipase.	Nitrogen	15-16	lipase C, hepatic type	Rattus norvegicus	87-101
2827010-5	1988	sra5 strains failed to survive prolonged nitrogen starvation in the presence of exogenous cAMP.	Nitrogen	41-49	3',5'-cyclic-nucleotide phosphodiesterase PDE2	Saccharomyces cerevisiae S288C	0-4
3236220-2	1988	The bacterial strain mA3 capable of utilizing 3-aminophenol as the sole source of carbon, energy and nitrogen for growth was isolated from an enrichment culture and identified as an Arthrobacter species.	Nitrogen	101-109	cholinergic receptor, nicotinic, alpha polypeptide 3	Mus musculus	21-24
3168078-6	1988	Incubations of the lung, the nasal olfactory mucosa, the hard palate and the liver in CO- or N2-atmospheres or in the presence of the cytochrome P-450-inhibitor metyrapone showed decreased formation of tissue-bound 3H from the 3H-labelled 4-ipomeanol, indicating a role of cytochrome P-450 in the metabolism of 4-ipomeanol in the various tissues.	Nitrogen	93-95	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	273-289
3132577-1	1988	During exposure to the leukoattractant FMLP (N-formyl-L-methionyl-L-leucyl-L-phenylalanine) human polymorphonuclear leukocytes (PMNL) exhibit a bimodal pattern of luminol-enhanced chemiluminescence (LECL) with distinct early extracellular and later-occurring intracellular membrane-associated oxidative responses [4, 7, 14].	Nitrogen	45-47	formyl peptide receptor 1	Homo sapiens	39-43
3227109-1	1988	Initial photoinduced oxidative changes in the protein lysozyme were studied using the 337.1 nm radiation from a pulsed nitrogen laser without exogenous sensitizing compounds.	Nitrogen	119-127	lysozyme	Homo sapiens	54-62
2827762-5	1987	Study of 6-coordinate O2-CoII(TPP)(L) complexes (L = nitrogenous base) using 14N- and 15N-labeled ligands and porphyrins enabled a detailed analysis of coupling parameters for both pyrrole and axial nitrogens.	Nitrogen	199-208	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	25-29
3440702-2	1987	The N-chloroacetyl-modified peptides react well with sulfhydryl containing proteins such as 4-mercaptobutyrimide-modified bovine serum albumin to form stable protein-peptide conjugates.	Nitrogen	4-5	albumin	Homo sapiens	129-142
3689443-0	1987	Studies on N-demethylation of methamphetamine by means of purified guinea-pig liver flavin-containing monooxygenase.	Nitrogen	11-12	flavin-containing monooxygenase	Cavia porcellus	84-115
2823941-4	1987	In addition it was found that the secretion of erythropoietin was almost completely abrogated by tunicamycin, an inhibitor of N-linked glycosylation.	Nitrogen	126-127	erythropoietin	Homo sapiens	47-61
2842656-10	1987	These results indicate a role of phospholipid N-methylation in the regulation of sarcolemmal Ca2+ ATPase and low affinity ATP-independent Ca2+ binding.	Nitrogen	46-47	carbonic anhydrase 2	Rattus norvegicus	93-104
2827739-1	1987	Electron paramagnetic resonance (EPR) studies of the nitrosyl adduct of ferrous lactoperoxidase (LPO) confirm that the fifth axial ligand in LPO is bound to the iron via a nitrogen atom.	Nitrogen	172-180	lactoperoxidase	Homo sapiens	80-95
2827739-1	1987	Electron paramagnetic resonance (EPR) studies of the nitrosyl adduct of ferrous lactoperoxidase (LPO) confirm that the fifth axial ligand in LPO is bound to the iron via a nitrogen atom.	Nitrogen	172-180	lactoperoxidase	Homo sapiens	97-100
2827739-1	1987	Electron paramagnetic resonance (EPR) studies of the nitrosyl adduct of ferrous lactoperoxidase (LPO) confirm that the fifth axial ligand in LPO is bound to the iron via a nitrogen atom.	Nitrogen	172-180	lactoperoxidase	Homo sapiens	141-144
3121434-1	1987	A mutation has been identified that prevents Saccharomyces cerevisiae cells from growing on proline as the sole source of nitrogen, causes noninducible expression of the PUT1 and PUT2 genes, and is completely recessive.	Nitrogen	122-130	proline dehydrogenase	Saccharomyces cerevisiae S288C	170-174
3318851-6	1987	ApoB 100 is co-translationally N-glycosylated and 25% of the oligosaccharide chains is processed in the Golgi compartment.	Nitrogen	31-32	apolipoprotein B	Homo sapiens	0-8
2445505-4	1987	The fluorescent complex, monoclonal antibody-AFP-polyclonal antibody-biotin-streptavidin-BCPDA-Eu3+, is quantified by nitrogen laser excitation at 337.1 nm, the emission at 615 nm being monitored in an especially designed gated fluorometer working in a time-resolved mode.	Nitrogen	118-126	alpha fetoprotein	Homo sapiens	45-48
3121434-2	1987	In the put3-75 mutant, the basal level of expression (ammonia as nitrogen source) of PUT1-lacZ and PUT2-lacZ gene fusions as measured by beta-galactosidase activity is reduced 4- and 7-fold, respectively, compared with the wild-type strain.	Nitrogen	65-73	proline dehydrogenase	Saccharomyces cerevisiae S288C	85-89
2829053-0	1987	Synthesis and biological activity of N-methylated analogues of neurokinin A.	Nitrogen	37-38	tachykinin precursor 1	Homo sapiens	63-75
3435945-0	1987	Effect of ginsenoside-Rb2 on nitrogen compounds in streptozotocin-diabetic rats.	Nitrogen	29-37	RB transcriptional corepressor like 2	Rattus norvegicus	22-25
3626763-8	1987	Plasma NPY levels were the lowest (65.4 +/- 8.8 fmol/ml, n-10, Mean +/- SEM) in salt-restricted and the highest (151.2 +/- 25 fmol/ml, n-14, p less than 0.02) in salt-loaded animals.	Nitrogen	57-58	neuropeptide Y	Rattus norvegicus	7-10
3329678-3	1987	We found that in liquid medium containing bovine serum albumin (BSA) as the sole nitrogen source, at pH 4 and 27 degrees C, the sensitivity of proteinase detection was considerably greater than when assayed on BSA agar at 37 degrees C. This observation is due, in part, to temperature sensitivity of proteinase induction.	Nitrogen	81-89	endogenous retrovirus group K member 25	Homo sapiens	143-153
16593857-1	1987	Establishment of a nitrogen-fixing root nodule is accompanied by a developmentally regulated expression of nodulin genes, only some of which, the so-called early nodulin genes, are expressed in stages preceding actual nitrogen fixation.	Nitrogen	19-27	NOD3	Glycine max	107-114
3626536-5	1987	TTR, TF, and RBP correlated significantly with TB and NTB VIS nitrogen and TB CAR nitrogen.	Nitrogen	62-70	transferrin	Rattus norvegicus	5-7
3626536-6	1987	The correlation of NTB VIS nitrogen with TTR, TF, and RBP (r range = 0.70-0.85, P less than 0.001) was higher than for TB rats (r range = 0.53-0.57, P less than 0.005).	Nitrogen	27-35	transferrin	Rattus norvegicus	46-48
3626536-7	1987	The correlation of TB carcass nitrogen (r range = 0.47-0.51, P less than 0.01) with TTR, TF, and RBP was higher than for NTB carcass nitrogen which was not significant (r range = 0.25-0.37, P less than 0.57).	Nitrogen	30-38	transferrin	Rattus norvegicus	89-91
3271463-2	1987	Both are in the free base form and have an intramolecular-hydrogen bond between N10 of the acridine and the nitrogen atom of the carboxamide substituent.	Nitrogen	108-116	nuclear receptor subfamily 4 group A member 1	Homo sapiens	80-83
16593857-1	1987	Establishment of a nitrogen-fixing root nodule is accompanied by a developmentally regulated expression of nodulin genes, only some of which, the so-called early nodulin genes, are expressed in stages preceding actual nitrogen fixation.	Nitrogen	19-27	NOD3	Glycine max	162-169
16593857-1	1987	Establishment of a nitrogen-fixing root nodule is accompanied by a developmentally regulated expression of nodulin genes, only some of which, the so-called early nodulin genes, are expressed in stages preceding actual nitrogen fixation.	Nitrogen	218-226	NOD3	Glycine max	107-114
16593857-1	1987	Establishment of a nitrogen-fixing root nodule is accompanied by a developmentally regulated expression of nodulin genes, only some of which, the so-called early nodulin genes, are expressed in stages preceding actual nitrogen fixation.	Nitrogen	218-226	NOD3	Glycine max	162-169
3563885-8	1987	Thus use of a 45% BCAA-enriched solution infused in patients after surgery results in a significant increase in forearm muscle uptake of the BCAA that is not demonstrated in whole-body nitrogen economics.	Nitrogen	185-193	AT-rich interaction domain 4B	Homo sapiens	18-22
2820951-13	1987	Cytochrome P-450 (pHP3) catalyzed N-demethylation of benzphetamine and aminopyrine and denitrification of 1-nitropropane.	Nitrogen	34-35	cytochrome P450 2C14	Oryctolagus cuniculus	18-22
3588082-0	1987	Supplementation of pooled human milk with casein hydrolysate: energy and nitrogen balance and weight gain composition in very low birth weight infants.	Nitrogen	73-81	Weaning weight-maternal milk	Bos taurus	32-36
2435722-9	1987	In a pulse-chase experiment using tunicamycin to block N-glycosylation, alpha 1-macroglobulin secretion was totally inhibited.	Nitrogen	55-56	pregnancy-zone protein	Rattus norvegicus	72-93
3031084-8	1987	Analysis of the amino acid sequence of ribophorin I suggested that the polypeptide has a simple transmembrane disposition with a rather hydrophilic carboxy terminal segment of 150 amino acids exposed on the cytoplasmic face of the membrane, and a luminal domain of 414 amino acids containing three potential N-glycosylation sites.	Nitrogen	308-309	ribophorin I	Rattus norvegicus	39-51
3102604-1	1987	The phorbol myristate acetate (PMA) stimulation of the human neutrophil NADPH-oxidase has been demonstrated through the activation of protein kinase C (PK-C), using light membrane fractions from nitrogen-cavitated cells.	Nitrogen	195-203	proline rich transmembrane protein 2	Homo sapiens	134-150
3108533-4	1987	A mean decrease in transferrin of 12.95 mg/dl was associated with a mean decrease in nitrogen balance of 0.92 g/day, whereas a mean increase in transferrin of 21.04 mg/dl was associated with a mean increase in nitrogen balance of 1.49 g/day; the correlation between changes in transferrin with changes in nitrogen balance was statistically significant (p = 0.02).	Nitrogen	85-93	transferrin	Homo sapiens	19-30
3108533-4	1987	A mean decrease in transferrin of 12.95 mg/dl was associated with a mean decrease in nitrogen balance of 0.92 g/day, whereas a mean increase in transferrin of 21.04 mg/dl was associated with a mean increase in nitrogen balance of 1.49 g/day; the correlation between changes in transferrin with changes in nitrogen balance was statistically significant (p = 0.02).	Nitrogen	210-218	transferrin	Homo sapiens	144-155
3108533-4	1987	A mean decrease in transferrin of 12.95 mg/dl was associated with a mean decrease in nitrogen balance of 0.92 g/day, whereas a mean increase in transferrin of 21.04 mg/dl was associated with a mean increase in nitrogen balance of 1.49 g/day; the correlation between changes in transferrin with changes in nitrogen balance was statistically significant (p = 0.02).	Nitrogen	210-218	transferrin	Homo sapiens	144-155
3108533-4	1987	A mean decrease in transferrin of 12.95 mg/dl was associated with a mean decrease in nitrogen balance of 0.92 g/day, whereas a mean increase in transferrin of 21.04 mg/dl was associated with a mean increase in nitrogen balance of 1.49 g/day; the correlation between changes in transferrin with changes in nitrogen balance was statistically significant (p = 0.02).	Nitrogen	210-218	transferrin	Homo sapiens	144-155
3108533-4	1987	A mean decrease in transferrin of 12.95 mg/dl was associated with a mean decrease in nitrogen balance of 0.92 g/day, whereas a mean increase in transferrin of 21.04 mg/dl was associated with a mean increase in nitrogen balance of 1.49 g/day; the correlation between changes in transferrin with changes in nitrogen balance was statistically significant (p = 0.02).	Nitrogen	210-218	transferrin	Homo sapiens	144-155
3108533-10	1987	Changes in transferrin were more significantly related to changes in nitrogen balance, and from the results of this study, measurement of serum transferrin can be recommended as a useful parameter in following the nutritional status of patients receiving nutritional support.	Nitrogen	69-77	transferrin	Homo sapiens	11-22
3108533-10	1987	Changes in transferrin were more significantly related to changes in nitrogen balance, and from the results of this study, measurement of serum transferrin can be recommended as a useful parameter in following the nutritional status of patients receiving nutritional support.	Nitrogen	69-77	transferrin	Homo sapiens	144-155
3102604-1	1987	The phorbol myristate acetate (PMA) stimulation of the human neutrophil NADPH-oxidase has been demonstrated through the activation of protein kinase C (PK-C), using light membrane fractions from nitrogen-cavitated cells.	Nitrogen	195-203	proline rich transmembrane protein 2	Homo sapiens	152-156
3104258-3	1987	High-spin forms of cytochrome P-450 purified from 3-methylcholanthrene-pretreated rats (MC-P-448-H) or hamsters (P-488 ham-II) showed higher catalytic activity for N-hydroxylation of phenetidine than three other low-spin forms of cytochrome P-450 purified from the same animals or from phenobarbital-pretreated rats.	Nitrogen	164-165	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	19-35
3548194-7	1987	As the insulin infusion progressed, the urea nitrogen, uric acid and bicarbonate levels fell as well.	Nitrogen	45-53	insulin	Homo sapiens	7-14
3104258-3	1987	High-spin forms of cytochrome P-450 purified from 3-methylcholanthrene-pretreated rats (MC-P-448-H) or hamsters (P-488 ham-II) showed higher catalytic activity for N-hydroxylation of phenetidine than three other low-spin forms of cytochrome P-450 purified from the same animals or from phenobarbital-pretreated rats.	Nitrogen	164-165	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	230-246
3311606-6	1987	Insulin decreased the incorporation of the infused glutamine amide-15N into urinary uric acid as well as the excretion of other N-derived urinary uric acid (P less than 0.05), which resulted in a significant decrease in total urinary uric acid (P less than 0.05).	Nitrogen	69-70	insulin	Gallus gallus	0-7
2879838-3	1987	High performance liquid chromatographic analysis of deproteinized liver samples indicated that labeled nitrogen is exchanged rapidly among components of: mitochondrial aspartate aminotransferase and glutamate dehydrogenase reactions and cytoplasmic aspartate aminotransferase and alanine aminotransferase reactions (t1/2 for the exchange of label toward equilibrium is on the order of seconds).	Nitrogen	103-111	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	168-194
2879838-3	1987	High performance liquid chromatographic analysis of deproteinized liver samples indicated that labeled nitrogen is exchanged rapidly among components of: mitochondrial aspartate aminotransferase and glutamate dehydrogenase reactions and cytoplasmic aspartate aminotransferase and alanine aminotransferase reactions (t1/2 for the exchange of label toward equilibrium is on the order of seconds).	Nitrogen	103-111	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	249-275
3814146-4	1987	Each repetitive domains contains 4 cysteines at precisely the same positions and as many as 28 possible N-glycosylation sites are found in the CEA peptide region agreeing with high carbohydrate content of purified CEA.	Nitrogen	104-105	CEA cell adhesion molecule 3	Homo sapiens	143-146
3814146-4	1987	Each repetitive domains contains 4 cysteines at precisely the same positions and as many as 28 possible N-glycosylation sites are found in the CEA peptide region agreeing with high carbohydrate content of purified CEA.	Nitrogen	104-105	CEA cell adhesion molecule 3	Homo sapiens	214-217
3040973-4	1987	Both types of receptors are N- and possibly O-glycosylated but the turkey beta 1 receptor has only complex carbohydrates whereas the human beta 2 receptor has in addition oligo mannosidic polysaccharidic moiety.	Nitrogen	28-29	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	74-80
3658091-1	1987	CBA/N (Xid) mice classically present a genetically determined immune deficiency.	Nitrogen	4-5	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	7-10
3778491-2	1986	The flexibility of the pyrrolidine ring due to the pyramidal character of nitrogen has been defined in terms of two projection angles delta 1 and delta 2.	Nitrogen	74-82	delta like non-canonical Notch ligand 1	Homo sapiens	134-153
20501140-6	1987	Our histochemical and histophotometrical data strongly account for the assumption that aspartate aminotransferase, beyond its numerous functions in general amino acid and nitrogen metabolism, is involved in the synthesis and/or catabolism of glutamate and aspartate used as excitatory transmitters.	Nitrogen	171-179	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	87-113
3773884-14	1986	These results suggest that the activational state of Ns can affect the stimulation of adenylate cyclase by calmodulin and forskolin.	Nitrogen	53-55	calmodulin	Bos taurus	107-117
2946263-1	1986	Phosphofructokinase (PFK) purified from rabbit skeletal muscle is fully inactivated after being frozen in liquid nitrogen for 30 s and thawed.	Nitrogen	113-121	ATP-dependent 6-phosphofructokinase, muscle type	Oryctolagus cuniculus	0-19
2946263-1	1986	Phosphofructokinase (PFK) purified from rabbit skeletal muscle is fully inactivated after being frozen in liquid nitrogen for 30 s and thawed.	Nitrogen	113-121	ATP-dependent 6-phosphofructokinase, muscle type	Oryctolagus cuniculus	21-24
3536852-1	1986	The putP gene encodes a proline permease required for Salmonella typhimurium LT2 to grow on proline as the sole source of nitrogen.	Nitrogen	122-130	sodium/proline symporter	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	4-8
2948220-7	1986	The results indicate that receptors for IGF-I and insulin in human brain are structurally distinct from the corresponding receptors in human placenta, the structural heterogeneity of the receptors involves differences in N-linked glycosylation, particularly the terminal processing steps, and EGF receptors are present in human brain and human placenta but are structurally similar in these tissues.	Nitrogen	221-222	insulin like growth factor 1	Homo sapiens	40-45
3790542-6	1986	Compositional analyses and 125I concanavalin A and 125I wheat germ agglutinin binding suggest that chicken hemopexin has a mixture of three fucose-free N-linked bi- and triantennary oligosaccharides.	Nitrogen	152-153	hemopexin	Gallus gallus	107-116
2876389-1	1986	We present an atomic model for glutamine synthetase, an enzyme of central importance in bacterial nitrogen metabolism, from X-ray crystallography.	Nitrogen	98-106	glutamate-ammonia ligase	Homo sapiens	31-51
3800318-6	1986	It is concluded that the metabolic activation of 2-naphthylamine proceeds via N-hydroxylation which is preferentially catalysed by the 3-methylcholanthrene inducible forms of cytochrome P-450, whereas ring-hydroxylation appears to be a deactivation pathway.	Nitrogen	78-79	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	175-191
3760089-1	1986	A gas chromatographic method using nitrogen-selective detection for the quantitative determination of nanogram amounts of chlorimipramine, chlorpromazine and their nor1 and nor2 derivatives in plasma is described.	Nitrogen	35-43	nuclear receptor subfamily 4 group A member 3	Homo sapiens	164-168
3090723-0	1986	Positive nitrogen balance with human growth hormone and hypocaloric intravenous feeding.	Nitrogen	9-17	growth hormone 1	Homo sapiens	37-51
3090723-5	1986	Administration of GH decreased weight loss, caused retention of nitrogen, potassium, and phosphorus in amounts closely matching their proportions in skeletal muscle, and stimulated insulin production.	Nitrogen	64-72	growth hormone 1	Homo sapiens	18-20
3086996-5	1986	Insulin also significantly reduced the efflux of isoleucine, tyrosine, phenylalanine, glutamine, and total amino acid nitrogen from forearm muscle.	Nitrogen	118-126	insulin	Homo sapiens	0-7
3729411-0	1986	N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic microsomal cytochrome P-450: isozyme specificity and role of cytochrome b5.	Nitrogen	0-1	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	87-103
2425031-1	1986	A mouse mAb, CT-3, recognizes on chicken T cells a complex of three polypeptides, Mr 20,000, 19,000, and 17,000, two of which are N-glycosylated.	Nitrogen	130-131	cancer antigen 1	Homo sapiens	13-17
3722145-5	1986	It is also noted that the effect of the "extra" electron in the nitrogen base Co(II) oxy complexes, in some ways, parallels the effect of the lone pair electrons of thiolate in the oxy-P-450cam complex.	Nitrogen	64-72	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	78-84
3089784-1	1986	N-Glycosidically linked glycopeptides released by mild alkaline treatment of human factor VIII/von Willebrand factor (FVIII/vWF) were fractionated by serial affinity chromatography on columns of Sepharose linked to concanavalin A (ConA) and Lens culinaris agglutinin (LCA).	Nitrogen	0-1	von Willebrand factor	Homo sapiens	124-127
3086996-6	1986	These findings, along with the partial reduction in the excretion of 3-methylhistidine and nitrogen, suggest that insulin, in combination with infused calories and protein, decreases the loss of muscle protein after trauma.	Nitrogen	91-99	insulin	Homo sapiens	114-121
3700466-0	1986	Three types of low density lipoprotein receptor-deficient mutant have pleiotropic defects in the synthesis of N-linked, O-linked, and lipid-linked carbohydrate chains.	Nitrogen	110-111	low-density lipoprotein receptor	Cricetulus griseus	15-47
3790080-2	1986	The fragment was found to undergo structural transformations over the pH range 3.5-4.5 known to cause N-F transition in serum albumin.	Nitrogen	102-103	albumin	Homo sapiens	120-133
3089123-3	1986	Nitrogen balance was significantly better when MCT/LCT was infused and the greater levels of plasma ketones and lower plasma triglyceride levels suggested that MCT was more readily metabolised in these patients.	Nitrogen	0-8	solute carrier family 16 member 1	Homo sapiens	47-50
3089123-3	1986	Nitrogen balance was significantly better when MCT/LCT was infused and the greater levels of plasma ketones and lower plasma triglyceride levels suggested that MCT was more readily metabolised in these patients.	Nitrogen	0-8	solute carrier family 16 member 1	Homo sapiens	160-163
3487561-9	1986	Utilization of urea nitrogen for milk production was improved by adding dried whey to diets of early lactation cows.	Nitrogen	20-28	Weaning weight-maternal milk	Bos taurus	33-37
3722547-7	1986	Nonprotein nitrogen content of milk increased as dietary protein increased.	Nitrogen	11-19	Weaning weight-maternal milk	Bos taurus	31-35
3082891-2	1986	Treatment of human umbilical vein endothelial cells with tunicamycin inhibited N-linked glycosylation of nascent vWf and the resulting pro-vWf monomers failed to dimerize.	Nitrogen	79-80	von Willebrand factor	Homo sapiens	113-116
3955081-3	1986	In the presence of tunicamycin, an inhibitor of N-glycosylation, the secretion of angiotensinogen as well as total protein and albumin secretion were diminished.	Nitrogen	48-49	angiotensinogen	Rattus norvegicus	82-97
3517494-0	1986	Insulin stimulates branched chain amino acid uptake and diminishes nitrogen flux from skeletal muscle of injured patients.	Nitrogen	67-75	insulin	Homo sapiens	0-7
3517494-7	1986	In trauma patients, total nitrogen release (3843 +/- 1383 nM/100 ml/min) was inhibited during insulin administration (819 +/- 314, P less than 0.05).	Nitrogen	26-34	insulin	Homo sapiens	94-101
3005565-2	1986	The IR and ESR spectral studies imply dibasic tetradentate behavior of the ligand bonding through "thiolo" sulfur, enolic oxygen, and hydrazinic nitrogens in a polymeric structure.	Nitrogen	145-154	esterase 5 regulator	Mus musculus	11-14
3271870-2	1986	Cytochrome P-450 preferentially oxidized the nitrogen to nitrogen bond of 1,2-disubstituted hydrazines and hydrazides, while monoamine oxidase oxidized the nitrogen to nitrogen bond of all the classes of hydrazine derivatives that were tested.	Nitrogen	45-53	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-16
3271870-2	1986	Cytochrome P-450 preferentially oxidized the nitrogen to nitrogen bond of 1,2-disubstituted hydrazines and hydrazides, while monoamine oxidase oxidized the nitrogen to nitrogen bond of all the classes of hydrazine derivatives that were tested.	Nitrogen	57-65	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-16
3271870-2	1986	Cytochrome P-450 preferentially oxidized the nitrogen to nitrogen bond of 1,2-disubstituted hydrazines and hydrazides, while monoamine oxidase oxidized the nitrogen to nitrogen bond of all the classes of hydrazine derivatives that were tested.	Nitrogen	57-65	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-16
3271870-2	1986	Cytochrome P-450 preferentially oxidized the nitrogen to nitrogen bond of 1,2-disubstituted hydrazines and hydrazides, while monoamine oxidase oxidized the nitrogen to nitrogen bond of all the classes of hydrazine derivatives that were tested.	Nitrogen	57-65	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-16
3271870-4	1986	In addition, cytochrome P-450 preferentially oxidized the carbon to nitrogen bond of monoalkylhydrazines; this reaction resulted in the formation of aldehyde metabolites (via hydrazone intermediates).	Nitrogen	68-76	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	13-29
2875480-4	1986	In fact [125I]N--Tyr--SRIF binds to membranes not only of human GH-secreting adenomas, but also of prolactinomas.	Nitrogen	14-15	growth hormone 1	Homo sapiens	64-66
3962333-11	1986	These data suggested that N-demethylation and N-defurfurylation of furfenorex were mainly mediated by cytochrome P-450 but not cytochrome P-448.	Nitrogen	26-27	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	102-118
3962333-11	1986	These data suggested that N-demethylation and N-defurfurylation of furfenorex were mainly mediated by cytochrome P-450 but not cytochrome P-448.	Nitrogen	46-47	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	102-118
3023826-5	1986	P70 appears to be the aglycosylated form of gp95, the presumptive intracellular precursor of the receptor-related species gp120 that is secreted by A431 but not Hep 3B cells; gp120 has a complex pattern of N-linked glycosylation, with consequent molecular weight and charge heterogeneity.	Nitrogen	206-207	ubiquitin associated and SH3 domain containing B	Homo sapiens	0-3
3023826-5	1986	P70 appears to be the aglycosylated form of gp95, the presumptive intracellular precursor of the receptor-related species gp120 that is secreted by A431 but not Hep 3B cells; gp120 has a complex pattern of N-linked glycosylation, with consequent molecular weight and charge heterogeneity.	Nitrogen	206-207	sortilin 1	Homo sapiens	44-48
3712106-1	1986	The effect of L-methionine supplementation on the utilization of a soy protein isolate (SPI) was evaluated by short-term nitrogen balance studies in young women.	Nitrogen	121-129	chromogranin A	Homo sapiens	88-91
3494003-2	1986	Alkylation of the amide nitrogen in spiperone by NCA [18F]fluorobromoethane in the presence of a strong base gave 5 (Method A).	Nitrogen	24-32	CEA cell adhesion molecule 4	Homo sapiens	49-52
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	139-140	immunoglobulin kappa variable 2D-38 (pseudogene)	Homo sapiens	84-103
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	139-140	immunoglobulin kappa variable 2D-38 (pseudogene)	Homo sapiens	191-206
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	145-146	immunoglobulin kappa variable 2D-38 (pseudogene)	Homo sapiens	84-103
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	145-146	immunoglobulin kappa variable 2D-38 (pseudogene)	Homo sapiens	191-206
3934016-4	1985	N-Glycosylation of secreted angiotensinogen was inhibited using tunicamycin.	Nitrogen	0-1	angiotensinogen	Homo sapiens	28-43
3917039-2	1985	On deoxygenation, the conformation of this region changes substantially, allowing complexation only through the ND1 nitrogen atom of His-113, a much less favorable interaction.	Nitrogen	116-124	mitochondrially encoded NADH dehydrogenase 1	Homo sapiens	112-115
2999766-0	1985	Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: evidence that the ntrA product is a sigma factor.	Nitrogen	12-20	neuronal growth regulator 1	Homo sapiens	38-42
33874234-4	1985	The fungus readily utilizes the soluble protein bovine serum albumin (BSA) as sole nitrogen and carbon source, and produces lower yields on less soluble plant and animal proteins.	Nitrogen	83-91	albumin	Homo sapiens	55-68
2999766-0	1985	Products of nitrogen regulatory genes ntrA and ntrC of enteric bacteria activate glnA transcription in vitro: evidence that the ntrA product is a sigma factor.	Nitrogen	12-20	neuronal growth regulator 1	Homo sapiens	128-132
2999766-1	1985	In enteric bacteria the products of two nitrogen regulatory genes, ntrA and ntrC, activate transcription of glnA, the structural gene encoding glutamine synthetase, both in vivo and in vitro.	Nitrogen	40-48	neuronal growth regulator 1	Homo sapiens	67-71
2999766-1	1985	In enteric bacteria the products of two nitrogen regulatory genes, ntrA and ntrC, activate transcription of glnA, the structural gene encoding glutamine synthetase, both in vivo and in vitro.	Nitrogen	40-48	glutamate-ammonia ligase	Homo sapiens	143-163
3863100-10	1985	The remaining two-thirds of PSAP is resistant to bacterial collagenase digestion and contains a possible N-glycosylation site near the carboxyl terminus.	Nitrogen	105-106	prosaposin	Canis lupus familiaris	28-32
4084506-5	1985	The positions of the C = N stretch in the deuterated pigment and the deuterated pigments regenerated with 11-cis-15-deuterioretinal or 11-cis-retinal containing 13C at carbon 15 are indicative that the Schiff-base linkage is protonated in rhodopsin, bathorhodopsin, and isorhodopsin.	Nitrogen	25-26	rhodopsin	Homo sapiens	239-248
3898078-4	1985	There is one potential N-linked glycosylation site on MuTNF, in contrast to human TNF, which lacks any such site.	Nitrogen	23-24	tumor necrosis factor	Homo sapiens	56-59
3861610-7	1985	The lentil lectin-reactive glycophorin A molecules increased to Mr = 39,000 during chase and obtained sialic acids after 9 min of chase reflecting terminal N- and O-glycosylation.	Nitrogen	156-157	glycophorin A (MNS blood group)	Homo sapiens	27-40
2996591-11	1985	This superoxide-mediated oxidation represents another pathway for N-oxidation by cytochrome P-450.	Nitrogen	66-67	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	81-97
24310878-1	1985	Leghemoglobin is a major component of the nitrogen-fixing nodules formed by legumes in association with bacterial symbionts of the genusRhizobium.	Nitrogen	42-50	leghemoglobin A	Glycine max	0-13
2993005-7	1985	Insulin, an ingredient of N2, can substitute for the complete N2 formula.	Nitrogen	26-28	insulin	Homo sapiens	0-7
2993005-7	1985	Insulin, an ingredient of N2, can substitute for the complete N2 formula.	Nitrogen	62-64	insulin	Homo sapiens	0-7
3928916-2	1985	Plasma fibronectin was significantly decreased from 330 +/- 22 to 154 +/- 11 micrograms/ml (p less than 0.001) from the postabsorptive to starved state which was accompanied by appropriate changes in body weight, anthropometric measurements, and nitrogen balance.	Nitrogen	246-254	fibronectin 1	Homo sapiens	7-18
2996591-8	1985	In the first reaction, N-hydroxylation of phentermine occurs by a normal cytochrome P-450 pathway.	Nitrogen	23-24	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	73-89
3862428-8	1985	The discrepancy between the proportions of the monoferric transferrin species noted with control cells was enhanced at all concentrations of methylamine, most markedly at 10 mM when the C/N ratio was 2.4.	Nitrogen	188-189	transferrin	Homo sapiens	58-69
3987688-0	1985	The occurrence, subcellular localization and partial purification of diamine acetyltransferase in the yeast Candida boidinii grown on spermidine or putrescine as sole nitrogen source.	Nitrogen	167-175	acetyltransferase	Saccharomyces cerevisiae S288C	77-94
3921236-11	1985	Studies with space-filling models of the drugs the metabolism of which is associated with debrisoquine 4-hydroxylase in the literature indicated that all can be fitted to a general structure in which a basic nitrogen is about 5 A away from the site of carbon hydroxylation and a hydrophobic domain is near the site of hydroxylation.	Nitrogen	208-216	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	90-116
3849428-7	1985	During biosynthesis, HA-T antigen is co-translationally translocated across the membrane of the ER, the signal peptide is cleaved and a mannose-rich oligosaccharide is attached to the polypeptide (T antigen contains one potential N-linked glycosylation site at Asn154).	Nitrogen	230-231	histocompatibility 49	Mus musculus	21-25
3987688-1	1985	The yeast Candida boidinii when grown on spermidine, diaminopropane, putrescine or cadaverine as sole nitrogen source contains an N-acetyltransferase capable of acetylating the primary amino groups of spermine, spermidine, acetylspermidines, acetylputrescine and alpha, omega-diaminoalkanes.	Nitrogen	102-110	acetyltransferase	Saccharomyces cerevisiae S288C	132-149
2981143-5	1985	Intra-arterial infusion of AT-II raised the T/N ratio more obviously than did intravenous infusion of the drug, with less rise in the peripheral blood pressure.	Nitrogen	46-47	angiotensinogen	Homo sapiens	27-32
3919738-4	1985	However, glucuronidation of the N-hydroxy-N-acetyl derivative of 2-AN was 40 and 17 times faster than the corresponding derivatives of 2-AF and 4-ABP respectively.	Nitrogen	32-33	glutamate receptor interacting protein 2	Rattus norvegicus	146-149
3918429-10	1985	The increase of Sm-C/IGF-I correlated temporally with entry into positive nitrogen balance.	Nitrogen	74-82	insulin like growth factor 1	Homo sapiens	21-26
3977857-9	1985	These data implicate aspartate aminotransferase in the transfer of amino acid carbon and nitrogen from the mitochondria to the cytosol, and suggest that oxaloacetate, via phosphoenolpyruvate carboxykinase, can serve as an intermediate on the route of pyruvate formation for muscle alanine synthesis.	Nitrogen	89-97	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	21-47
3917669-5	1985	Studies on the effects of pretreatment of animals with either phenobarbital or Aroclor 1254 suggest that cytochrome P-450 isozymes catalyzed both N-deethylation and hydroxylation reactions.	Nitrogen	146-147	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	105-121
3884968-1	1985	Plasma somatomedin-C (Sm-C)/insulin-like growth factor I (IGF-I) concentrations have been shown to reflect changes in nitrogen balance induced by manipulation of nutrient intake.	Nitrogen	118-126	insulin like growth factor 1	Homo sapiens	7-20
3884968-1	1985	Plasma somatomedin-C (Sm-C)/insulin-like growth factor I (IGF-I) concentrations have been shown to reflect changes in nitrogen balance induced by manipulation of nutrient intake.	Nitrogen	118-126	insulin like growth factor 1	Homo sapiens	28-56
3884968-1	1985	Plasma somatomedin-C (Sm-C)/insulin-like growth factor I (IGF-I) concentrations have been shown to reflect changes in nitrogen balance induced by manipulation of nutrient intake.	Nitrogen	118-126	insulin like growth factor 1	Homo sapiens	58-63
3918475-10	1985	These results suggest that central vein parenteral nutrition utilizing a 45 percent BCAA enriched solution can promote nitrogen retention without serious side effects in moderately to severely stressed patients.	Nitrogen	119-127	AT-rich interaction domain 4B	Homo sapiens	84-88
16831703-16	1985	Stimulation of insulin and growth hormone secretion may be contributing factors in the better nitrogen utilization.	Nitrogen	94-102	insulin	Homo sapiens	15-22
3856097-3	1985	The I-Ak alpha-chain has two N-linked glycosylation sites at Asn-82 and Asn-122.	Nitrogen	29-30	Fc gamma receptor and transporter	Homo sapiens	9-20
3917299-3	1985	During the first week of therapy, both children had evidence of the metabolic effects of increased growth hormone secretion--i.e., nitrogen retention, demonstrated by decreased nitrogen excretion (P less than 0.05), and increased urinary calcium excretion (P less than 0.01).	Nitrogen	131-139	growth hormone 1	Homo sapiens	99-113
3917299-3	1985	During the first week of therapy, both children had evidence of the metabolic effects of increased growth hormone secretion--i.e., nitrogen retention, demonstrated by decreased nitrogen excretion (P less than 0.05), and increased urinary calcium excretion (P less than 0.01).	Nitrogen	177-185	growth hormone 1	Homo sapiens	99-113
3917299-6	1985	Growth hormone--releasing factor can restore growth hormone secretion and its biologic effects, including an increase in nitrogen retention, an increase in serum somatomedin C, and acceleration of linear growth in children with growth hormone deficiency.	Nitrogen	121-129	growth hormone releasing hormone	Homo sapiens	0-32
3917299-6	1985	Growth hormone--releasing factor can restore growth hormone secretion and its biologic effects, including an increase in nitrogen retention, an increase in serum somatomedin C, and acceleration of linear growth in children with growth hormone deficiency.	Nitrogen	121-129	growth hormone 1	Homo sapiens	45-59
2862826-18	1985	Both CCK-8(ns) and DA could be sulfated in vivo, this enzymic reaction generally requiring active sulfate (PAPS).	Nitrogen	11-13	cholecystokinin	Homo sapiens	5-8
3917621-6	1985	Both enteral and parenteral nitrogen caused a similar increase in plasma insulin levels.	Nitrogen	28-36	insulin	Homo sapiens	73-80
3967341-13	1985	The results of this study suggest that the formation of phenolic and N-hydroxy metabolites of 2-FAA in both hepatic and mammary microsomes of lactating rats is catalyzed by similar form(s) of cytochrome P-450 induced by pretreatment with 3-MC or beta-NF.	Nitrogen	69-70	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	192-208
3936597-1	1985	The primary structural analysis of O- and N-linked carbohydrate chains of the C-1-esterase inhibitor purified from normal serum was carried out by 400-MHz 1H-NMR spectroscopy.	Nitrogen	42-43	complement C1s	Homo sapiens	78-90
6548452-2	1984	A solution containing human glycophorin A was introduced between an alkylated cover glass with lipid layers from soybean phospholipids and a bare glass slide, and was then put in a glass dish which was frozen outside by liquid nitrogen.	Nitrogen	227-235	glycophorin A (MNS blood group)	Homo sapiens	28-41
6099695-4	1984	The non-enzymatic mitochondrial CCl4 activation is not inhibited by CO and proceeds equally well under air or nitrogen.	Nitrogen	110-118	C-C motif chemokine ligand 4	Rattus norvegicus	32-36
6390435-1	1984	The ligand N alpha, B1-(6-biotinylamido)hexanoyl-insulin was attached noncovalently to Sepharose 4B immobilized succinoylavidin to form an insulin-affinity resin.	Nitrogen	11-12	insulin	Homo sapiens	49-56
6390435-1	1984	The ligand N alpha, B1-(6-biotinylamido)hexanoyl-insulin was attached noncovalently to Sepharose 4B immobilized succinoylavidin to form an insulin-affinity resin.	Nitrogen	11-12	insulin	Homo sapiens	139-146
6240545-0	1984	Altered immunologic function and nitrogen metabolism associated with depression of plasma growth hormone.	Nitrogen	33-41	growth hormone 1	Homo sapiens	90-104
6240545-1	1984	The specific role of endogenous growth hormone in regulating nitrogen metabolism during surgical stress and infection remains unclear.	Nitrogen	61-69	growth hormone 1	Homo sapiens	32-46
6506758-1	1984	Relative participation of flavin-containing mono-oxygenase and cytochrome P-450 systems in N-hydroxylation of and formaldehyde release from methamphetamine were studied in vitro using liver microsomes of guinea-pigs and rats.	Nitrogen	91-92	cytochrome P450 3A14	Cavia porcellus	63-79
6150098-0	1984	A possible cytochrome P-450-mediated N-oxidation of diethylcarbamazine.	Nitrogen	37-38	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	11-27
6525296-1	1984	Nanogram amounts of chlorimipramine, chlorpromazine and their Nor1- and Nor2-metabolites were detected in plasma by GLC with nitrogen-sensitive detection.	Nitrogen	125-133	nuclear receptor subfamily 4 group A member 3	Homo sapiens	62-66
6381484-3	1984	Myeloperoxidase catalyzed the oxidation of chloride (Cl-) by H2O2 to yield hypochlorous acid (HOCl), which reacted with endogenous nitrogen compounds to yield derivatives containing nitrogen-chlorine (N-Cl) bonds.	Nitrogen	131-139	myeloperoxidase	Homo sapiens	0-15
6381305-5	1984	Concentrations of insulin in plasma were high for the prevailing concentrations of glucose, and peak urinary excretion of nitrogen coincided with maximum levels of insulin.	Nitrogen	122-130	insulin	Homo sapiens	164-171
6541664-4	1984	Synthesis of milk protein increased during postruminal infusions of protein as indicated by the increased casein nitrogen fraction in milk.	Nitrogen	113-121	Weaning weight-maternal milk	Bos taurus	13-17
6541664-4	1984	Synthesis of milk protein increased during postruminal infusions of protein as indicated by the increased casein nitrogen fraction in milk.	Nitrogen	113-121	Weaning weight-maternal milk	Bos taurus	134-138
6541664-5	1984	All protein infusions improved efficiency of use of absorbed nitrogen for synthesis of milk protein.	Nitrogen	61-69	casein beta	Bos taurus	87-99
6381637-11	1984	For example, CBA/N-marrow derived B cells differentiated effectively and survived for long periods in F1 male mice (xid----xid) but not in F1 female mice (xid----normal).	Nitrogen	17-18	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	116-119
6426787-2	1984	This N-demethylation is mediated by cytochrome P-450 in the microsomal fractions, and in mitochondrial preparations it has been found to occur via N- methylolpentamethylmelamine .	Nitrogen	5-6	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	36-52
6466534-2	1984	In the present study RIF-1 clones have been exposed to nitrogen mustard, aniline mustard and chlorambucil, and to nitrosoureas BCNU, MeCCNU and chlorozotocin, in order to evaluate whether or not the different physiochemical and biological activities of these agents would affect the patterns of drug sensitivity obtained for melphalan and CCNU.	Nitrogen	55-63	replication timing regulatory factor 1	Mus musculus	21-26
6466534-3	1984	Irrespective of the different lipophilicities, transport properties and chemical reactivities of the nitrogen mustards, RIF-1 clones showed the same pattern of sensitivity as previously observed for melphalan.	Nitrogen	101-109	replication timing regulatory factor 1	Mus musculus	120-125
6466534-5	1984	These data suggest (a) that the variation in the sensitivity of RIF-1 clones to treatment by the nitrogen mustards is unlikely to reflect differences in either membrane permeability or in drug transport and (b) that the ploidy dependent nitrosourea responses shown by RIF-1 clones similarly do not reflect differences in drug uptake.	Nitrogen	97-105	replication timing regulatory factor 1	Mus musculus	64-69
6148216-8	1984	Together with the results obtained with the inhibitors, these findings implicate participation of alternative isoenzymatic forms of cytochrome P-450 in N-demethylation and 4-hydroxylation of TAM.	Nitrogen	152-153	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	132-148
6744468-0	1984	Interactions of nitrogen heterocycles with cytochrome P-450 and monooxygenase activity.	Nitrogen	16-24	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	43-77
6203988-1	1984	Candida albicans was able to produce a keratinolytic proteinase (KPase) when cultivated in a medium containing human stratum corneum as a nitrogen source.	Nitrogen	138-146	endogenous retrovirus group K member 25	Homo sapiens	53-63
6378975-9	1984	HTG-HDL3 is denser than N-HDL3 and demonstrates compositional abnormalities similar to those of HTG-LDL.	Nitrogen	24-25	HDL3	Homo sapiens	26-30
6087417-3	1984	The omega-chain variant analogs of prostacyclin (PGI2) and PGD2 in which n-amyl side-chain has been replaced by a cyclohexyl group have been prepared and their cardiovascular activities have been compared to those of <protein-id="259307">BW-245C(Fig.	Nitrogen	14-15	prostaglandin D2 synthase	Homo sapiens	59-63
6443063-3	1984	Nitrogen absorption of LFM and SPI was 80%.	Nitrogen	0-8	chromogranin A	Homo sapiens	31-34
6443063-5	1984	On the other hand, nitrogen retention was higher in infants 11 and 12 months old with moderate malnutrition fed the SPI formula.	Nitrogen	19-27	chromogranin A	Homo sapiens	116-119
6708544-5	1984	In addition, spectral studies with rat adrenal mitochondria and a soluble preparation of human placental cytochrome P-450scc showed that binding of the 22-amine derivative to the enzyme produces difference spectra characteristic of nitrogen bonding to the heme; this indicates that the heme is positioned close to C-22 in the steroid-enzyme complex.	Nitrogen	232-240	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	105-124
16663546-3	1984	Nodule slices prepared and scanned under nitrogen gas showed a ferrous leghemoglobin absorption spectrum.	Nitrogen	41-49	leghemoglobin A	Glycine max	71-84
16829429-3	1984	In contrast, their effects on immune and reparative cells appear additive to insulin"s anabolic effect augmenting tissue repair and increasing immunologic defense, but at the expense of muscle nitrogen.	Nitrogen	193-201	insulin	Homo sapiens	77-84
6147017-1	1984	In this paper, it was first shown that under various conditions of nitrogen supply the rifamycin yield was positively correlated with the mycelial specific activity of glutamine synthetase (GS), then the enhancing effect of glutamine, the product of GS, on rifamycin biosynthesis was demonstrated with resting cell system.	Nitrogen	67-75	glutamate-ammonia ligase	Homo sapiens	168-188
6147017-1	1984	In this paper, it was first shown that under various conditions of nitrogen supply the rifamycin yield was positively correlated with the mycelial specific activity of glutamine synthetase (GS), then the enhancing effect of glutamine, the product of GS, on rifamycin biosynthesis was demonstrated with resting cell system.	Nitrogen	67-75	glutamate-ammonia ligase	Homo sapiens	190-192
6704271-4	1984	Nitrogen excretion did not exceed 100 ml min-1 and was measurable (8 ml min-1) at 100 min.	Nitrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	72-77
6697962-11	1984	The heterogeneity of secreted angiotensinogen can be fully accounted for by differences in N-glycosylation of asparagine residues of the molecule.	Nitrogen	91-92	angiotensinogen	Rattus norvegicus	30-45
6533010-0	1984	Dietary phenolics and betel nut extracts as modifiers of N-nitrosation in rat and man.	Nitrogen	57-58	NUT midline carcinoma, family member 1	Rattus norvegicus	28-31
6420374-6	1984	Apparent nitrogen balance was positive pre-operatively and became less so post-operatively whether insulin was given or not.	Nitrogen	9-17	insulin	Homo sapiens	99-106
24310256-10	1984	Thus, leghemoglobin and nodulin genes are switched on soon after infection, prior to nodule morphogenesis, and the switch occurs prior to and is independent of nitrogen fixation activity.	Nitrogen	160-168	leghemoglobin A	Glycine max	6-19
6151113-1	1984	In enteric bacteria products of nitrogen regulatory genes ntrA, ntrB and ntrC are known to regulate transcription both positively and negatively at glnA, the structural gene encoding glutamine synthetase [L-glutamate:ammonia-ligase (ADP-forming), EC 6.3.1.2].	Nitrogen	32-40	neuronal growth regulator 1	Homo sapiens	58-62
6151113-1	1984	In enteric bacteria products of nitrogen regulatory genes ntrA, ntrB and ntrC are known to regulate transcription both positively and negatively at glnA, the structural gene encoding glutamine synthetase [L-glutamate:ammonia-ligase (ADP-forming), EC 6.3.1.2].	Nitrogen	32-40	glutamate-ammonia ligase	Homo sapiens	183-203
24310256-10	1984	Thus, leghemoglobin and nodulin genes are switched on soon after infection, prior to nodule morphogenesis, and the switch occurs prior to and is independent of nitrogen fixation activity.	Nitrogen	160-168	NOD3	Glycine max	24-31
6719937-0	1984	The role of cytochrome P-450 in the dual pathways of N-demethylation of N,N-dimethylaniline by hepatic microsomes.	Nitrogen	53-54	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	12-28
6360215-4	1983	It agglutinated human red blood cells with A1 and B specificity at concentrations of 12 and 72 micrograms nitrogen/ml, respectively.	Nitrogen	106-114	BCL2 related protein A1	Homo sapiens	43-51
6661247-0	1983	Hepatic microsomal cytochrome p-450-dependent N-demethylation of methylguanidine.	Nitrogen	46-47	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	19-35
6661247-5	1983	The direct involvement of cytochrome P-450 in the N-demethylation is supported by the observations that addition of methylguanidine to purified cytochrome P-450 preparation caused a type I spectral change and that inhibitors of cytochrome P-450, such as carbon monoxide and metyrapone, markedly decreased the rate of demethylation.	Nitrogen	50-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	26-42
6661247-5	1983	The direct involvement of cytochrome P-450 in the N-demethylation is supported by the observations that addition of methylguanidine to purified cytochrome P-450 preparation caused a type I spectral change and that inhibitors of cytochrome P-450, such as carbon monoxide and metyrapone, markedly decreased the rate of demethylation.	Nitrogen	50-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	144-160
6360215-8	1983	For minimal agglutination of human A1 and B red blood cells 2.4 and 72.0 micrograms nitrogen/ml, respectively, of lectin I were required.	Nitrogen	84-92	BCL2 related protein A1	Homo sapiens	35-43
6661247-5	1983	The direct involvement of cytochrome P-450 in the N-demethylation is supported by the observations that addition of methylguanidine to purified cytochrome P-450 preparation caused a type I spectral change and that inhibitors of cytochrome P-450, such as carbon monoxide and metyrapone, markedly decreased the rate of demethylation.	Nitrogen	50-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	144-160
6870907-0	1983	Correlations between spin equilibrium shift, reduction rate, and N-demethylation activity in liver microsomal cytochrome P-450 and a series of benzphetamine analogues as substrates.	Nitrogen	65-66	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	110-126
6316979-14	1983	The results support earlier findings that microsomal enzymes differ in immature and mature rat liver and suggest that N-hydroxylation of 2-FAA, the activation required for carcinogenesis, and specific ring-hydroxylations are catalyzed by different cytochrome P-450 isozymes.	Nitrogen	118-119	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	248-264
6688621-9	1983	Binding of the 23-amine to P-450scc also caused formation of a low spin complex with an absorption maximum at 422 nm, indicative of a nitrogen-donor ligand.	Nitrogen	134-142	cytochrome P450 family 11 subfamily A member 1	Homo sapiens	27-35
6631308-6	1983	Guanethidine, phentolamine and propranolol all produced a significant fall in the basal concentrations of vasopressin, while guanethidine, phenoxybenzamine and propranolol blocked the increase seen on breathing 12% oxygen in nitrogen.	Nitrogen	225-233	arginine vasopressin	Rattus norvegicus	106-117
28310544-3	1983	The annual depositions of NO -3 -N and NH +4 -N amounted to 96.3 and 56.0 mg m-2 ground area yr-1, respectively.	Nitrogen	32-34	NBL1, DAN family BMP antagonist	Homo sapiens	26-31
6311300-1	1983	Stabilized intermediate redox states of cytochrome c are generated by radiolytic reduction of initially oxidized enzyme in glass matrices at liquid nitrogen temperature.	Nitrogen	148-156	cytochrome c, somatic	Homo sapiens	40-52
6413737-9	1983	It was concluded that cytochrome P-450 associated with aminopyrine N-demethylation is different from that of aniline hydroxylation in the hydrophobic environment of microsomes, and sulfate or chloride causes an enhancement of only cytochrome P-450 activity associated with the demethylation.	Nitrogen	67-68	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	22-38
6301926-5	1983	Our results support the possibility of a soluble interaction between N2,O2"-dibutyryl cyclic guanosine 3":5"-monophosphate and the peptides of cholecystokinin-gastrin family that is specific for the COOH-terminal (receptor binding) region of these peptides, that is dependent on the concentration of N2,O2"-dibutyryl cyclic guanosine 3":5"-monophosphate, and that correlates with concentrations that inhibit biologic activity.	Nitrogen	69-71	cholecystokinin	Homo sapiens	143-158
6301926-5	1983	Our results support the possibility of a soluble interaction between N2,O2"-dibutyryl cyclic guanosine 3":5"-monophosphate and the peptides of cholecystokinin-gastrin family that is specific for the COOH-terminal (receptor binding) region of these peptides, that is dependent on the concentration of N2,O2"-dibutyryl cyclic guanosine 3":5"-monophosphate, and that correlates with concentrations that inhibit biologic activity.	Nitrogen	300-302	cholecystokinin	Homo sapiens	143-158
6413737-9	1983	It was concluded that cytochrome P-450 associated with aminopyrine N-demethylation is different from that of aniline hydroxylation in the hydrophobic environment of microsomes, and sulfate or chloride causes an enhancement of only cytochrome P-450 activity associated with the demethylation.	Nitrogen	67-68	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	231-247
6135582-11	1983	These observations also support previous findings that N-demethylation and 4" hydroxylation are, in the main, catalyzed by different isozymes of cytochrome P-450.	Nitrogen	55-56	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	145-161
6870842-0	1983	N-alkylation of the haem moiety of cytochrome P-450 caused by substituted dihydropyridines.	Nitrogen	0-1	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	35-51
6870842-1	1983	Preferential attack of different pyrrole nitrogen atoms after induction of various cytochrome P-450 isoenzymes.	Nitrogen	41-49	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	83-99
6870842-10	1983	The isomeric composition of N-ethylprotoporphyrin produced in vivo and in vitro depends on the cytochrome P-450 isoenzyme that predominates at the time of treatment, suggesting a role for the apo-cytochrome in directing alkylation on to one of the pyrrole nitrogens.	Nitrogen	256-265	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	95-111
6832094-5	1983	Various species of cytochrome P-450 preparations showed markedly different activity in N-hydroxylation and mutagenic activation of Trp-P-2, Glu-P-1 and IQ.	Nitrogen	87-88	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	19-35
6865917-10	1983	The substrate affinities of the cytochrome P-450 primarily responsible for the N-demethylation of Bz in U- and PB-microsomes differ markedly.	Nitrogen	79-80	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	32-48
6684153-7	1983	The linear regression equations obtained between nitrogen intake (X: mg N/kg/day) and the apparent nitrogen balance (Y: mg N/kg/day) were as follows: SPI, Y = 0.298X-35.2; fish protein, Y = 0.365X-31.8; mixed protein, Y = 0.423X-38.3.	Nitrogen	49-57	chromogranin A	Homo sapiens	150-153
6684153-7	1983	The linear regression equations obtained between nitrogen intake (X: mg N/kg/day) and the apparent nitrogen balance (Y: mg N/kg/day) were as follows: SPI, Y = 0.298X-35.2; fish protein, Y = 0.365X-31.8; mixed protein, Y = 0.423X-38.3.	Nitrogen	99-107	chromogranin A	Homo sapiens	150-153
6684153-8	1983	The nitrogen requirement for maintenance of nitrogen equilibrium determined from the regression equation was 118.1 +/- 15.4 mg N/kg/day for SPI, 87.1 +/- 17.2 mg N/kg/day for fish protein and 90.5 +/- 17.1 mg N/kg/day for mixed protein.	Nitrogen	4-12	chromogranin A	Homo sapiens	140-143
6602656-6	1983	In contrast, xid-bearing CBA/N, DBA/2.xid, and MRL.xid mice showed marked reductions in both anti-DNA and anti-TNP precursors relative to non-xid mice.	Nitrogen	29-30	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	13-16
6343842-1	1983	The activities of the proline-specific permease (PUT4) and the general amino acid permease (GAP1) of Saccharomyces cerevisiae vary 70- to 140-fold in response to the nitrogen source of the growth medium.	Nitrogen	166-174	amino acid permease GAP1	Saccharomyces cerevisiae S288C	92-96
6832094-6	1983	A high spin form of cytochrome P-450, isolated from the liver of PCB-treated rats, showed very high activity in N-hydroxylation of Trp-P-2, Glu-P-1 and 2-aminofluorene, although its activity was very low in benzo(a)pyrene hydroxylation.	Nitrogen	112-113	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	20-36
6832094-6	1983	A high spin form of cytochrome P-450, isolated from the liver of PCB-treated rats, showed very high activity in N-hydroxylation of Trp-P-2, Glu-P-1 and 2-aminofluorene, although its activity was very low in benzo(a)pyrene hydroxylation.	Nitrogen	112-113	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	131-138
6832094-7	1983	The present results indicate that different species of cytochrome P-450 are involved in the N-hydroxylation and mutagenic activation of aromatic amines.	Nitrogen	92-93	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	55-71
6682428-7	1983	Milk protein (total nitrogen x 6.38) produced by cows fed soybean meal treated with formaldehyde was less than by cows fed untreated soybean meal during days 22 to 63 and during days 22 to 119 (47 versus 44 kg/cow and 103 versus 97 kg/cow).	Nitrogen	20-28	Weaning weight-maternal milk	Bos taurus	0-4
6401725-2	1983	Cathepsin B has been shown to catalyze the transfer of the N alpha-benzyloxycarbonyl-L-lysyl residue from the corresponding p-nitrophenyl ester substrate to water and dipeptide nucleophiles.	Nitrogen	59-60	cathepsin B	Bos taurus	0-11
6681614-6	1983	The changes in somatomedin-C during fasting and refeeding correlated significantly with mean daily nitrogen balance (r = 0.90).	Nitrogen	99-107	insulin like growth factor 1	Homo sapiens	15-28
6681614-8	1983	The correlation between changes in somatomedin-C and nitrogen balance suggests that the former are directly related to changes in protein synthesis and may be helpful in assessing the response to nutritional therapy.	Nitrogen	53-61	insulin like growth factor 1	Homo sapiens	35-48
6664258-4	1983	We conclude that the N-acetylation of newly synthesized MSH is associated with release of the hormone.	Nitrogen	21-22	proopiomelanocortin	Homo sapiens	56-59
6345421-4	1983	In the control group there was a sustained nitrogen balance after three weeks; in Gp A the nitrogen losses increased markedly during T3 treatment.	Nitrogen	91-99	glycophorin A (MNS blood group)	Homo sapiens	82-86
6827092-6	1983	These findings may be explained by the fact that N-acetylated angiotensin II resists degradation by amino peptidases and thus retains its structure in the immunogen and by the fact that the (1-7)-heptapeptide has lost the immunodominant carboxy-terminal epitope, thus emphasizing the desired amino terminal determinant.	Nitrogen	49-50	angiotensinogen	Homo sapiens	62-76
6286107-10	1982	We conclude that both estrogen and prolactin play a role in the growth of the N-nitrosomethylurea-induced rat mammary tumor.	Nitrogen	78-79	prolactin	Rattus norvegicus	35-44
6131376-1	1982	The effects of transcription and translation inhibitors on NADP-glutamate dehydrogenase and glutamine synthetase synthesis in nitrogen-starving Ankistrodesmus braunii cells have been studied.	Nitrogen	126-134	glutamate-ammonia ligase	Homo sapiens	92-112
16829385-6	1982	Metabolic adaptation to the fasting state was lost in patients with deep sepsis and nitrogen losses were increased with greater decreases in plasma albumin and transferrin.	Nitrogen	84-92	albumin	Homo sapiens	148-155
16829385-6	1982	Metabolic adaptation to the fasting state was lost in patients with deep sepsis and nitrogen losses were increased with greater decreases in plasma albumin and transferrin.	Nitrogen	84-92	transferrin	Homo sapiens	160-171
16662735-4	1982	The results indicate that inhibition of glutamine synthetase and thereby inhibition of photorespiratory nitrogen cycling restricts the sink capacity for glycolate in the photorespiratory carbon cycle.	Nitrogen	104-112	glutamate-ammonia ligase	Homo sapiens	40-60
6812232-9	1982	We conclude that this 45% BCAA-enriched solution may be safely administered to patients with postoperative traumatic injury and results in nitrogen equilibrium over a 5-day period.	Nitrogen	139-147	AT-rich interaction domain 4B	Homo sapiens	26-30
6288676-10	1982	The results provide persuasive evidence that oxidation of the nitrogen in DDEP by cytochrome P-450 proceeds in one-electron steps.	Nitrogen	62-70	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	82-98
6128670-1	1982	The effects of transcription and translation inhibitors on NADP-glutamate dehydrogenase and glutamine synthetase synthesis in nitrogen-starving Ankistrodesmus braunii cells have been studied.	Nitrogen	126-134	glutamate-ammonia ligase	Homo sapiens	92-112
7083399-6	1982	But the same doses of both drugs decreased glutathione S-transferase levels in rat brain and increased cytochrome P-450 dependent N-demethylation of p-chloro-N-methylaniline.	Nitrogen	130-131	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	103-119
7083159-4	1982	2-[(2,4-Dichloro-6-phenyl)phenoxy]ethylamine, a potent cytochrome P-450 inhibitor, decreased microsomal N-OH-AF formation by 96, 83, 70, and 46% in the rat, dog, human, and pig, respectively; and further addition of methimazole, a high-affinity flavin-containing monooxygenase substrate, abolished the residual N-hydroxylating activity.	Nitrogen	104-105	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	55-71
7103934-16	1982	The combination of experimental results from the protein studies and the peptide analyses provides strong evidence for the structure of the Ni(II)-binding site of HSA as one that involves the alpha-amino nitrogen atom, two deprotonated peptide nitrogen atoms, the imidazole nitrogen atom and the side-chain carboxy group of the aspartic acid residue.	Nitrogen	204-212	albumin	Homo sapiens	163-166
6122677-1	1982	To determine the ability of mutations in glnA, the gene for glutamine synthetase (GS), to regulate nitrogen assimilatory enzymes, we assayed histidase and GS in 34 glnA (Gln(-)) strains.	Nitrogen	99-107	glutamate-ammonia ligase	Homo sapiens	60-80
6279506-5	1982	Divalent cations with Ca2+ antagonistic action such as manganese M(n2+), nickel (Ni2+), and cobalt (Co2+) blocked the aldosterone secretory response to AII, ACTH, and K+.	Nitrogen	67-70	angiotensinogen	Homo sapiens	152-155
6124421-4	1982	This enzyme cleaves N-terminal arginyl residues unless the adjacent penultimate residue is proline as is the case for bradykinin.	Nitrogen	20-21	kininogen 1	Homo sapiens	118-128
6802829-3	1982	A 200% stimulation of N-demethylation by cytochrome b5 was obtained at cytochrome P-450 reductase:cytochrome P-450 ratios similar to those in microsomes, compared to only a 20% stimulation at a ratio of 1:1.	Nitrogen	22-23	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	71-87
6802829-3	1982	A 200% stimulation of N-demethylation by cytochrome b5 was obtained at cytochrome P-450 reductase:cytochrome P-450 ratios similar to those in microsomes, compared to only a 20% stimulation at a ratio of 1:1.	Nitrogen	22-23	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	98-114
7103934-16	1982	The combination of experimental results from the protein studies and the peptide analyses provides strong evidence for the structure of the Ni(II)-binding site of HSA as one that involves the alpha-amino nitrogen atom, two deprotonated peptide nitrogen atoms, the imidazole nitrogen atom and the side-chain carboxy group of the aspartic acid residue.	Nitrogen	244-252	albumin	Homo sapiens	163-166
7103934-16	1982	The combination of experimental results from the protein studies and the peptide analyses provides strong evidence for the structure of the Ni(II)-binding site of HSA as one that involves the alpha-amino nitrogen atom, two deprotonated peptide nitrogen atoms, the imidazole nitrogen atom and the side-chain carboxy group of the aspartic acid residue.	Nitrogen	244-252	albumin	Homo sapiens	163-166
6978738-1	1982	The orientational change of the absorbing dipole of the retinal chromophore in vertebrate rhodopsin (rhodo) upon photo-excitation to bathorhodopsin (batho), lumirhodopsin (lumi) and isorhodopsin (iso), has been studied by polarized absorption and linear dichroism measurements on magnetically oriented frog rod suspensions that were blocked at liquid nitrogen temperature.	Nitrogen	351-359	rhodopsin	Homo sapiens	90-99
7039035-6	1982	However, CBA/N, but not F1 leukocytes, stimulated MIF release and not proliferation by CBA/J responders, whereas C3H/HN leukocytes stimulated proliferative responses but not MIF release by CBA/J responders.	Nitrogen	13-14	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	Mus musculus	50-53
7047425-3	1982	Comparison of the urinary nitrogen excretion with daily protein intake revealed that the nitrogen balance was equilibrated during PSF.	Nitrogen	89-97	insulin like growth factor binding protein 7	Homo sapiens	130-133
7036751-1	1982	In a glucose-free bicarbonate Ringer (5% CO2 in N2), insulin increased intracellular pH (pHi), as determined by [14C]dimethadione, by 0.12 +/- 0.02 and stimulated glycolysis, as monitored by anaerobic lactate production, by 42.9 +/- 3.5% in paired frog sartorius muscles.	Nitrogen	48-50	insulin	Homo sapiens	53-60
6274792-1	1981	The interaction of cytochalasin B-treated human neutrophils with the synthetic tripeptide, N-formyl-methionyl-leucyl-phenylalanine (FMLP) results in a time- and concentration-dependent generation of superoxide anion (O2-) by an extracellular release of granule-associated beta-glucuronidase and lysozyme from these cells.	Nitrogen	91-92	formyl peptide receptor 1	Homo sapiens	132-136
6752238-4	1982	Failure of insulin and growth hormone production have been associated with glucose intolerance, excessive urinary nitrogen loss and a fatal outcome.	Nitrogen	114-122	insulin	Homo sapiens	11-18
6752238-4	1982	Failure of insulin and growth hormone production have been associated with glucose intolerance, excessive urinary nitrogen loss and a fatal outcome.	Nitrogen	114-122	growth hormone 1	Homo sapiens	23-37
7317380-4	1981	The structure of the green porphyrin implicates a cytochrome P-450 destructive mechanism in which a species formed by catalytic oxidation of the acetylenic moiety reacts with the nitrogens of prosthetic heme.	Nitrogen	179-188	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	50-66
16662109-0	1981	Regulation of asparaginase, glutamine synthetase, and glutamate dehydrogenase in response to medium nitrogen concentrations in a euryhaline chlamydomonas species.	Nitrogen	100-108	glutamate-ammonia ligase	Homo sapiens	28-48
16662109-3	1981	Biosynthetic glutamine synthetase activity was 1.5 to 1.8 times greater in nitrogen-limited cells than cells grown at high levels of the three nitrogen sources.Conversely, glutamate dehydrogenase (both NADH- and NADPH-dependent activities) was greatest in cells grown at high levels of asparagine or ammonium, while nitrate-grown cells possessed little activity at all concentrations employed.	Nitrogen	75-83	glutamate-ammonia ligase	Homo sapiens	13-33
16662109-3	1981	Biosynthetic glutamine synthetase activity was 1.5 to 1.8 times greater in nitrogen-limited cells than cells grown at high levels of the three nitrogen sources.Conversely, glutamate dehydrogenase (both NADH- and NADPH-dependent activities) was greatest in cells grown at high levels of asparagine or ammonium, while nitrate-grown cells possessed little activity at all concentrations employed.	Nitrogen	143-151	glutamate-ammonia ligase	Homo sapiens	13-33
16662109-5	1981	Glutamine synthetase and asparaginase, apparently repressed by high levels of all three nitrogen sources, are perhaps regulated by a common mechanism responding to intracellular nitrogen depletion, as evidenced by low cellular protein content.	Nitrogen	88-96	glutamate-ammonia ligase	Homo sapiens	0-20
16662109-5	1981	Glutamine synthetase and asparaginase, apparently repressed by high levels of all three nitrogen sources, are perhaps regulated by a common mechanism responding to intracellular nitrogen depletion, as evidenced by low cellular protein content.	Nitrogen	178-186	glutamate-ammonia ligase	Homo sapiens	0-20
6796262-1	1981	Metabolic activation of a tryptophan pyrolysate, 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2), in liver microsomes from rats, mice, hamsters, guinea pigs, and rabbits was studied to know whether N-hydroxylation is a common obligatory step for mutagenic activation of Trp-P-2.	Nitrogen	200-201	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	90-97
6796262-7	1981	In bacterial mutagenesis test systems using Salmonella typhimurium TA 98, the number of revertants induced by Trp-P-2 was increased in parallel with the microsomal ability of the N-hydroxylation.	Nitrogen	179-180	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	110-117
6796262-8	1981	These results indicate that in all species examined N-hydroxylation is an essential metabolic step for mutagenic activation of Trp-P-2.	Nitrogen	52-53	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	127-134
7310805-3	1981	Further qualitative and quantitative assessment of the integrity of nitrogen mustard groups in angiotensin II was attempted in order to evaluate the significance of the observed biological results.	Nitrogen	68-76	angiotensinogen	Rattus norvegicus	95-109
6793678-2	1981	The oxygen affinity of SS blood (measured as P50) is significantly decreased when this blood is exposed for 30 min to nitrogen before the determination of the oxygen equilibrium curve.	Nitrogen	118-126	nuclear factor kappa B subunit 1	Homo sapiens	45-48
7197688-4	1981	The change in somatomedin C during fasting showed a highly significant correlation with the change in urinary urea nitrogen excretion (r = 0.74; P less than 0.001).	Nitrogen	115-123	insulin like growth factor 1	Homo sapiens	14-27
7197688-6	1981	The results of this study suggest that measurement of plasma somatomedin C provides a sensitive indicator of nitrogen loss and may be useful in monitoring the changes in protein metabolism that occur during alterations in nutritional status.	Nitrogen	109-117	insulin like growth factor 1	Homo sapiens	61-74
7020934-4	1981	Cytochrome P-450 with higher capacity to form the N-hydroxylated metabolite induced a larger number of his+ revertants.	Nitrogen	50-51	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-16
24276702-2	1981	In both steady-state cells and ones disturbed physiologically by changes in light or nitrogen supply the assimilation of NO3 appears to be limited by the activity of GS.	Nitrogen	85-93	NBL1, DAN family BMP antagonist	Homo sapiens	121-124
7240099-1	1981	Cellular levels of an L-asparaginase in a Chlamydomonas species were found to be greater in nitrogen-limited batch cultures than in batch cultures grown in ample nitrogen.	Nitrogen	162-170	asparaginase and isoaspartyl peptidase 1	Homo sapiens	22-36
7309708-3	1981	The various spectral data indicated that the Co(II) center has tetrahedral geometry (high-spin state) and is linked by two nitrogens and two oxygens.	Nitrogen	123-132	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	45-51
7021543-4	1981	The analysis of a peptide derived from the NH2-terminus of PE2 and containing 45% of the acetate-derived label in this protein leads us to conclude that at least a significant fraction of PE2 is also blocked by N-acetylation.	Nitrogen	43-44	ETS2 repressor factor	Homo sapiens	59-62
7021543-4	1981	The analysis of a peptide derived from the NH2-terminus of PE2 and containing 45% of the acetate-derived label in this protein leads us to conclude that at least a significant fraction of PE2 is also blocked by N-acetylation.	Nitrogen	43-44	ETS2 repressor factor	Homo sapiens	188-191
7240099-0	1981	Regulation of L-asparaginase in a Chlamydomonas species in response to ambient concentrations of combined nitrogen.	Nitrogen	106-114	asparaginase and isoaspartyl peptidase 1	Homo sapiens	14-28
7240099-1	1981	Cellular levels of an L-asparaginase in a Chlamydomonas species were found to be greater in nitrogen-limited batch cultures than in batch cultures grown in ample nitrogen.	Nitrogen	92-100	asparaginase and isoaspartyl peptidase 1	Homo sapiens	22-36
7020934-0	1981	Evidence for the involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole by cytochrome P-450 in the covalent binding to DNA.	Nitrogen	32-33	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	94-110
7020934-1	1981	The involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) by cytochrome P-450 in the formation of covalent binding of Trp-P-2 to DNA, the induction of his+ revertant in the Ames test, and the formation of the active metabolite were confirmed.	Nitrogen	19-20	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	79-86
7020934-1	1981	The involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) by cytochrome P-450 in the formation of covalent binding of Trp-P-2 to DNA, the induction of his+ revertant in the Ames test, and the formation of the active metabolite were confirmed.	Nitrogen	19-20	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	91-107
7020934-1	1981	The involvement of N-hydroxylation of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) by cytochrome P-450 in the formation of covalent binding of Trp-P-2 to DNA, the induction of his+ revertant in the Ames test, and the formation of the active metabolite were confirmed.	Nitrogen	19-20	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	148-155
6973550-5	1981	In the presence of air, the rates of increase of permeability and inactivation of GAPDH were 2.8- and 1.5-fold of those in the presence of N2.	Nitrogen	139-141	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	82-87
7240147-3	1981	System ASC, identified by its sodium ion dependency and intolerance of N-methylation of substrates, was found to be relatively insensitive to external pH and nutrient limitation.	Nitrogen	71-72	PYD and CARD domain containing	Homo sapiens	7-10
7252985-5	1981	In contrast simple substitution on the nitrogen of 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline with a variety of substituents gives compounds with greatly diminished inhibitory potencies (IC50 = 2 to greater than 100 muM) relative to SK&amp;F 64139.	Nitrogen	39-47	latexin	Homo sapiens	217-220
7240099-3	1981	Derepressed L-asparaginase activity did not disappear in the presence of high concentrations of medium nitrogen, indicating the absence of an asparaginase-degrading system.	Nitrogen	103-111	asparaginase and isoaspartyl peptidase 1	Homo sapiens	12-26
7251857-4	1981	Receptor number was unaffected by steroid exposure, but the steroids effected a decrease in association rate constant for the FMLP-receptor interaction (35% of N for 0.2 mg/ml MP), leading to decreased receptor-ligand affinity.	Nitrogen	160-161	formyl peptide receptor 1	Homo sapiens	126-139
7203958-1	1981	Human prostatic androgen receptor content can be measured reliably in either fresh or bulk tissue stored in liquid nitrogen using (3H) R 1881 at incubation conditions of 4 C for 20 hr.	Nitrogen	115-123	androgen receptor	Homo sapiens	16-33
6259258-2	1981	The oxidation of n-FMLP by phagocytosing neutrophils was inhibited by methionine, but not by methionine sulfoxide, leucine, or phenylalanine, confirming that it was the methionine moiety of n-FMLP that was oxidized.	Nitrogen	12-13	formyl peptide receptor 1	Homo sapiens	19-23
6259258-2	1981	The oxidation of n-FMLP by phagocytosing neutrophils was inhibited by methionine, but not by methionine sulfoxide, leucine, or phenylalanine, confirming that it was the methionine moiety of n-FMLP that was oxidized.	Nitrogen	12-13	formyl peptide receptor 1	Homo sapiens	192-196
6792262-3	1981	The mean +/- SE values of the areas subtended by the PRL curves in the 3 above tests were 54.7 +/- 155.81 vs 3677.3 +/- 520.30 ng/2h, p less than 0,01, 210.3 +/- 148.93 vs 1034.8 +/- 203.15 ng/2h, p less than 0.05 and 1476.8 +/- 275.13 vs 2148.6 +/- 682.06 ng/2h, NS, respectively, in the obese and in controls.	Nitrogen	264-266	prolactin	Homo sapiens	53-56
6787225-2	1981	The aim of this study was to determine the effect of a proprietary feed (Triosorbon MCT), containing 6.9 mmol K+/g N, on serum and urinary K in 13 patients requiring nutritional support.	Nitrogen	115-116	solute carrier family 16 member 1	Homo sapiens	84-87
7013841-6	1981	In Ringer containing Na+, the increase in pHi by insulin occurs when both metabolic and atmospheric sources of CO2 are eliminated by using a 100% N2 atmosphere.	Nitrogen	146-148	insulin	Homo sapiens	49-56
7275458-6	1981	Mean daily nitrogen loss was lower in Gp 2 and 3 (-3.2 and -2.9 g N/day respectively).	Nitrogen	11-19	glycoprotein 2	Homo sapiens	38-48
6947662-12	1981	These observations suggest that dietary carbohydrate and insulin also promote nitrogen retention and that ketogenic, high protein diets do not confer a unique protein sparing advantage.	Nitrogen	78-86	insulin	Homo sapiens	57-64
7005335-1	1981	The effects of the inhibitor of N-linked glycosylation, tunicamycin, on the synthesis of HLA-A and -B antigens in the human lymphoblastoid cell line JY are described.	Nitrogen	32-33	major histocompatibility complex, class I, A	Homo sapiens	89-101
7425847-13	1980	The experiments with the nitrogen metabolism are the basis for the statement that protein and fat together determine the amount of nitrogen retention for calves fed wth moderate milk protein.	Nitrogen	131-139	casein beta	Bos taurus	178-190
7205871-7	1981	These results establish that cathechols responsible for the production of the poison oak/ivy contact dermatitis in humans undergo a sequence of reactions in the presence of human serum albumin that lead to covalent attachment of the catechols to the protein via carbon-nitrogen bonds.	Nitrogen	269-277	albumin	Homo sapiens	179-192
6787391-4	1981	The reactivation of latent mutability in a Notch inversion resulted in reinversion of the original aberration, followed by reversion of N to N+.	Nitrogen	141-143	Notch	Drosophila melanogaster	43-48
7461904-4	1980	In sodium dodecyl phosphate solution at 45 degrees (Lys)n also undergoes a beta-to-helix transition in alkaline solution with a midpoint at pH 9.2, noting that dodecyl phosphoric acid has two dissociation constants with pKa of about 3 and 8.	Nitrogen	1-2	amyloid beta precursor protein	Homo sapiens	73-79
7451368-4	1980	These results when combined with mass spectral analysis and isotopic dilution measurements proved that the indole nitrogen of tryptophan was completely retained at N-10 of anthramycin.	Nitrogen	114-122	nuclear receptor subfamily 4 group A member 1	Homo sapiens	164-168
6771001-11	1980	A preliminary analysis showed this molecule to be an N-hydroxylated derivative of Trp-P-2.	Nitrogen	53-54	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	82-89
7397450-5	1980	Thus the restriction imposed on the free rotation of the phenyl ring about the carbon-imino nitrogen bond by the introduction of two ortho substituents appears to result in increased agonist activity on the histamine H(2)-receptor.	Nitrogen	92-100	histamine H2 receptor	Cavia porcellus	207-230
7414619-1	1980	Exposure of rats to a reduced oxygen tension (6% O2, 94% N2) for 6 h increased the serum enzyme and the histological lesions induced by carbon tetrachloride (CCl4).	Nitrogen	57-59	C-C motif chemokine ligand 4	Rattus norvegicus	158-162
6966283-3	1980	Human alpha 1-protease inhibitor has three oligosaccharide side chains attached to 3 separate asparaginyl residues of the protein by N-glycosyl linkages.	Nitrogen	133-134	serpin family A member 1	Homo sapiens	6-32
6776055-0	1980	[Effect of human growth hormone on nitrogen retention].	Nitrogen	35-43	growth hormone 1	Homo sapiens	17-31
7450792-0	1980	Radiation chemical studies on nucleic acids &amp; its constituents: Part I--base damage of thymine derivatives in air &amp; nitrogen.	Nitrogen	124-132	adenine phosphoribosyltransferase	Homo sapiens	45-48
6892785-2	1980	Helium and nitrogen increased the transition temperature by 0.021 and 0.006 degree C/atm, respectively, compared with 0.024 degrees C/atm for hydrostatic pressure.	Nitrogen	11-19	MCOPCT1	Homo sapiens	83-88
7450792-0	1980	Radiation chemical studies on nucleic acids &amp; its constituents: Part I--base damage of thymine derivatives in air &amp; nitrogen.	Nitrogen	124-132	adenine phosphoribosyltransferase	Homo sapiens	119-122
7375189-5	1980	The ratio showed a significant positive correlation with growth hormone response to insulin hypoglycemia (r = 0.58; P less than 0.001) and with the nitrogen retention response to short-term growth hormone therapy (r = 0.45; P less than 0.001).	Nitrogen	148-156	growth hormone 1	Homo sapiens	190-204
109441-4	1979	In agreement with this equation, the observed Vmax for benzphetamine N-demethylation was found to be directly proportional to the calculated concentration of the cytochrome P-450 .	Nitrogen	69-70	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	162-178
6245775-4	1980	(i) Activity loss was probably a result of severely perturbing the cytochrome c binding site since oxidase activity with a low molecular weight reductant (N,N,N",N"-tetramethylphenylenediamine) was unaltered.	Nitrogen	155-156	cytochrome c, somatic	Homo sapiens	67-79
6906261-7	1980	This suggests strongly that reactive derivatives of the unsaturated drugs act as electrophilic reagents and alkylate one of the pyrrole nitrogen atoms of cytochrome P-450.	Nitrogen	136-144	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	154-170
291627-0	1979	Statherin and the proline-rich parotid proteins PRP II and PRP IV as amino nitrogen sources for plaque-forming oral streptococci.	Nitrogen	69-83	prion protein	Homo sapiens	48-51
291627-0	1979	Statherin and the proline-rich parotid proteins PRP II and PRP IV as amino nitrogen sources for plaque-forming oral streptococci.	Nitrogen	69-83	prion protein	Homo sapiens	59-62
7364687-2	1980	When added at a level equal to 1% urea in an 80% concentrate steer diet and fed twice daily, SRU gave a ruminal ammonia-nitrogen peak 1 hr postfeeding of 32 mg/dl compared to a peak from prilled urea of 53 mg/dl at 30 minutes.	Nitrogen	120-128	inactive tyrosine-protein kinase PEAK1	Ovis aries	129-135
7389028-0	1980	Free radical intermediate in the N-demethylation of aminopyrine by catalase-cumene hydroperoxide system.	Nitrogen	33-34	catalase	Homo sapiens	67-75
7228301-4	1980	The third class of N-nitrosating agent involves an as yet incompletely characterized metal complex containing a ligand having the formula NO3.	Nitrogen	19-20	NBL1, DAN family BMP antagonist	Homo sapiens	138-141
6767183-3	1980	As an alkylating agent, DMS is a typical SN2 agent, attacking predominantly nitrogen sites in nucleic acids.	Nitrogen	76-84	solute carrier family 38 member 5	Homo sapiens	41-44
43771-2	1979	This enzyme enabled the organism to grow as well with asparagine as sole nitrogen source as with inorganic nitrogen sources (NO3-, NH4+).	Nitrogen	73-81	NBL1, DAN family BMP antagonist	Homo sapiens	125-128
43771-2	1979	This enzyme enabled the organism to grow as well with asparagine as sole nitrogen source as with inorganic nitrogen sources (NO3-, NH4+).	Nitrogen	107-115	NBL1, DAN family BMP antagonist	Homo sapiens	125-128
474757-2	1979	The hamsters were permitted free access to food and water or fasted for 16 h. PTH caused a phosphaturia in the fed hamster (fractional excretion of phosphate (FEPO4) increased from 5.8 +/- 1.3 to 27.4 +/- 4.6%, P less than 0.001) but not in the fasted hamster (from 9.9 +/- 2.5 to 12.4 +/- 2.5%, NS), whereas calcium excretion decreased significantly in both groups.	Nitrogen	296-298	parathyroid hormone	Rattus norvegicus	78-81
41244-1	1979	The product of the glnR gene is required for nitrogen regulation of the synthesis of glutamine synthesis (Gln synthetase) [L-glutamate:ammonia ligase (ADP-forming), EC 6.3.1.2] and two periplasmic transport proteins that are subject to nitrogen control in Salmonella.	Nitrogen	45-53	glutamate-ammonia ligase	Homo sapiens	125-149
544924-4	1979	When cell disruption was achieved by grinding in liquid nitrogen the purified microsome NADPH cytochrome c reductase specific activity was found to be 3.5 times greater than that of microsomes obtained after homogenization of the tissue.	Nitrogen	56-64	cytochrome c, somatic	Homo sapiens	94-106
36043-0	1979	Nitrogen and ammonia assimilation in the cyanobacteria: regulation of glutamine synthetase.	Nitrogen	0-8	glutamate-ammonia ligase	Homo sapiens	70-90
493200-0	1979	Birmingham Medical Research Expeditionary Society 1977 Expedition: effect of a Himalayan trek on whole body composition, nitrogen and potassium.	Nitrogen	121-129	potassium two pore domain channel subfamily K member 2	Homo sapiens	89-93
428391-9	1979	Loss of alpha-N-acetylglucosaminidase endocytosis after treatment with endoglucosaminidase H indicated that the recognition site of alpha-N-acetylglucosaminidase is located on N-glycosidically linked oligosaccharides of the high mannose type.	Nitrogen	14-15	N-acetyl-alpha-glucosaminidase	Homo sapiens	132-161
284349-3	1979	These effects show that the strength of the C=N bond and the degree of protonation of the Schiff base nitrogen are the same in bathorhodopsin, rhodopsin, and isorhodopsin.	Nitrogen	46-47	rhodopsin	Homo sapiens	132-141
492426-5	1979	We concluded that conservative treatment -- low nitrogen diet supplemented with sufficient calories and essential amino acids -- improved the nutritional state of uremic subjects, and decreased the metabolic production of MG and GSA.	Nitrogen	48-56	GNAS complex locus	Homo sapiens	229-232
284349-3	1979	These effects show that the strength of the C=N bond and the degree of protonation of the Schiff base nitrogen are the same in bathorhodopsin, rhodopsin, and isorhodopsin.	Nitrogen	102-110	rhodopsin	Homo sapiens	132-141
717283-1	1978	Use of a liquid nitrogen container for convenient transport of frozen mammary carcinoma tissue for hormone-receptor assays is described.	Nitrogen	16-24	nuclear receptor subfamily 4 group A member 1	Homo sapiens	99-115
425134-1	1979	The nitrogen metabolism in rats with toxic affection of the liver caused by administration of CCl4 was studied as affected by the amino acid mixture moriamine S-2.	Nitrogen	4-12	C-C motif chemokine ligand 4	Rattus norvegicus	94-98
642651-4	1978	Hemoglobin and serum albumin increased significantly on ED and nitrogen balance performed on 7 patients was in equilibrium or positive.	Nitrogen	63-71	albumin	Homo sapiens	21-28
567217-1	1978	Role of glutathione peroxidase, catalase, and formaldehyde dehydrogenase in reactions relating to N-demethylation by the cytochrome P-450 system.	Nitrogen	98-99	catalase	Homo sapiens	32-40
373767-5	1978	It was found that insulin, and to a lesser extent glucagon, when infused into fasting subjects (1) rendered muscle significantly more reduced, and (2) resulted in a diminution in urinary nitrogen excretion.	Nitrogen	187-195	insulin	Homo sapiens	18-25
624443-1	1978	Amino acid tolerance tests were performed before and after jejunoileal bypass surgery for morbid obesity to determine whether an enteric factor(s) originating in the bypassed jejunum and/or ileum potentiates the insulin response to oral nitrogen loading.	Nitrogen	237-245	insulin	Homo sapiens	212-219
403073-3	1977	A double mutant (prc 1- leu2-) lacking carboxypeptidase Y and auxotrophic for leucine is able to grow on the peptide benzyloxycarbonylglycylleucine (Cbz-Gly-Leu) as sole nitrogen source, indicating the existence of a second carboxypeptidase.	Nitrogen	170-178	3-isopropylmalate dehydrogenase	Saccharomyces cerevisiae S288C	24-28
23870-0	1978	[Kinetics of N-dealkylation of amines with participation of microsomal cytochrome P-450].	Nitrogen	13-14	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	71-87
592327-8	1977	A bis-quaternary ammonium compound with a flexible bridge that links the two nitrogen atoms was found to be more potent in inhibiting AcChE and less potent in inhibiting BuChE than a bis-quaternary ammonium compound with a rigid bridge.	Nitrogen	77-85	acetylcholinesterase (Cartwright blood group)	Homo sapiens	134-139
884985-1	1977	Heretofore, the technical difficulties encountered in the measurement of blood nitrogen tension (PN2) by gas chromatographic techniques effectively prevented the utilization of PN2 as a clinical tool to characterize mismatching of pulmonary ventilation and perfusion.	Nitrogen	79-87	amyloid beta precursor protein	Homo sapiens	97-100
863995-2	1977	Mass spectrometry to these derivatives shows that the TMS group is substituted on the indolic nitrogen (N1) and not the primary amino nitrogen.	Nitrogen	94-102	PYD and CARD domain containing	Homo sapiens	54-57
203022-6	1977	During somatotropin treatment there was a positive correlation between changes in urine volume and nitrogen balance (r = 0.67).	Nitrogen	99-107	growth hormone 1	Homo sapiens	7-19
560873-2	1977	In the presence of leghemoglobin (0.1mM), a 3-fold enhancement of nitrogen fixation occurred but the inhibitory effect of nitrite was delayed.	Nitrogen	66-74	leghemoglobin A	Glycine max	19-32
560873-5	1977	High nitrite levels could depress nitrogen fixation both by inactivation of nitrogenase and by conversion of leghemoglobin into an inactive form.	Nitrogen	34-42	leghemoglobin A	Glycine max	109-122
403391-4	1977	Excretion of 3-methylhistidine was unaltered, suggesting that the source of the N losses produced by glucagon did not derive from increased muscle proteolysis.	Nitrogen	80-81	glucagon	Homo sapiens	101-109
832379-1	1977	We raised high-titre antisera to two LSD-bovine serum albumin conjugates, one linked via the indole nitrogen, the other via the amide side-chain.	Nitrogen	100-108	albumin	Homo sapiens	48-61
557967-9	1977	The 15N-labelling of milk protein provides evidence for the fact that nitrogen from IBDU is utilized for the synthesis of milk in the cows.	Nitrogen	70-78	casein beta	Bos taurus	21-33
853543-3	1977	The arylating metabolite is formed by a cytochrome P-450 dependent N-hydroxylation process.	Nitrogen	67-68	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	40-56
15657-1	1977	A highly purified preparation of glutamine synthetase from chlorella grown on a medium containing nitrate as a sole source of nitrogen, was isolated and characterized by disc-electrophoresis and analytical ultracentrifugation.	Nitrogen	126-134	glutamate-ammonia ligase	Homo sapiens	33-53
835869-4	1977	The quantity B 1/2 (FRC/Vt) was relatively constant within an individual regardless of FRC or Vt and was named the nitrogen dilution constant (NDC).	Nitrogen	115-123	immunoglobulin kappa variable 7-3 (pseudogene)	Homo sapiens	13-26
830400-3	1977	Since N-hydroxylation of 2-FAA by hepatic microsomes is catalyzed by the mixed-function oxidase containing cytochrome P-450 or the 2-methylcholanthrene-inducible cytochrome P1-450, we examined whether these cytochromes are present in mammary microsomes.	Nitrogen	6-7	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	107-123
21651-0	1977	Glutamine synthetase control of nitrogen fixation in Rhizobia.	Nitrogen	32-40	glutamate-ammonia ligase	Homo sapiens	0-20
24271418-1	1976	The catalase inhibitor 3-amino-1,2,4-triazole causes an increase in dopamine-beta-hydroxylase (DBH) activity, as do other nitrogen-containing heterocyclics.	Nitrogen	122-130	catalase	Homo sapiens	4-12
973601-5	1976	The nitrogen content and the contents of the major human milk whey proteins, alpha-lactalbumin and lactoferrin, are very high for the first few days, then decrease rapidly and reach, thereafter, the more slowly declining level of mature milk.	Nitrogen	4-12	lactalbumin alpha	Homo sapiens	77-94
977936-7	1976	As based on the role of pentavalent nitrogen on substrate structure, it is apparent that PAP is to other acid phosphatases what the cholinesterases are to other esterases.	Nitrogen	36-44	acid phosphatase 3	Rattus norvegicus	89-92
8077-11	1976	This leads to a model involving intramolecular protonation of the Schiff base nitrogen in the retinal-opsin linkage of rhodopsin, which is consistent with the thermodynamic and spectroscopic properties of the system.	Nitrogen	78-86	rhodopsin	Homo sapiens	119-128
182488-8	1976	This supports the model that one of the pyridine nitrogens of metyrapone is coordinated to the iron of cytochrome P-450.	Nitrogen	49-58	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	103-119
949180-5	1976	The patterns of responses of mice receiving a lethal combination of LPS and VNC resembled those of mice receiving a lethal dose of LPS alone with respect to (i) hypothermia, (ii) retention of sulfobromophthalein, (iii) fibrinogen level, (iv) prothrombin activity, (v) blood urea nitrogen levels, and (vi) time of death.	Nitrogen	279-287	toll-like receptor 4	Mus musculus	68-71
949180-5	1976	The patterns of responses of mice receiving a lethal combination of LPS and VNC resembled those of mice receiving a lethal dose of LPS alone with respect to (i) hypothermia, (ii) retention of sulfobromophthalein, (iii) fibrinogen level, (iv) prothrombin activity, (v) blood urea nitrogen levels, and (vi) time of death.	Nitrogen	279-287	toll-like receptor 4	Mus musculus	131-134
180983-7	1976	The possibility is discussed that species Resting II, prepared with ethylene glycol, contains a -COCH2OH residue bound to a nitrogen ligand of molybdenum.	Nitrogen	124-132	cochlin	Oryctolagus cuniculus	97-101
1270652-7	1976	Milk protein composition was not affected by ration although nonprotein nitrogen of milk was highest from cows fed the urea-treated corn silages.	Nitrogen	72-80	Weaning weight-maternal milk	Bos taurus	84-88
1263443-11	1976	Ten nondehydrated rats (group III), given both glycerol and angiotensin II, developed a more severe form of acute renal failure (blood urea nitrogen 120.4 mg. per 100 ml.	Nitrogen	140-148	angiotensinogen	Rattus norvegicus	60-74
1247584-2	1976	Several vitamin B12 derivatives including descobalt B12 show unusual  inversion of their CD signs upon rapid cooling to liquid N2 temperature, although the room temperature CD signs are conserved by a slower cooling to the same temperature.	Nitrogen	127-129	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	16-19
2595-3	1976	Covalent labeling was achieved by reacting the label with human serum albumin under nitrogen at pH 9.4 and 20 degrees.	Nitrogen	84-92	albumin	Homo sapiens	64-77
2777-0	1976	Synthesis of angiotensin II antagonists containing N- and O-methylated and other amino acid residues.	Nitrogen	51-52	angiotensinogen	Rattus norvegicus	13-27
59648-6	1976	From the results of cross-reactivity experiments using N-triacylated ox insulins and human insulin, it was shown that antibody cross-reacting with iodo-ox insulin had most probably been produced to a localized area of the molecule.	Nitrogen	55-56	insulin	Homo sapiens	72-79
1247584-2	1976	Several vitamin B12 derivatives including descobalt B12 show unusual  inversion of their CD signs upon rapid cooling to liquid N2 temperature, although the room temperature CD signs are conserved by a slower cooling to the same temperature.	Nitrogen	127-129	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	52-55
11843-2	1976	Glutamine synthetase (GS) (E.C.6.3.1.2) activity in Chlorella cells decreased when NH4+ was added to nitrogen-free growth medium.	Nitrogen	101-109	glutamate-ammonia ligase	Homo sapiens	0-20
1188198-1	1975	The relationship between the partial pressure of N2 in the inspired air (PIN2), and the nitrogen transfer across the lungs (VN2), has been examined in 8 resting subjects, and a study made of the effect of diet upon this relationship.	Nitrogen	49-51	telomeric repeat binding factor 1	Homo sapiens	73-77
1182183-4	1975	Calculations of total energies and dipole moments were performed by the CNDO/2 and INDO methods for sp2 and sp3 hybridization of exocyclic nitrogen for different values of rotational angle phiC-N.	Nitrogen	139-147	Sp3 transcription factor	Homo sapiens	108-111
1176433-1	1975	Mycobacterium convolutum strain NPA-1 can utilize n-propylamine (NPA), isopropylamine (IPA), and 1,3-propane diamine (PD) as sole source of carbon, nitrogen, and energy.	Nitrogen	148-156	URB1 ribosome biogenesis homolog	Homo sapiens	32-37
1188198-1	1975	The relationship between the partial pressure of N2 in the inspired air (PIN2), and the nitrogen transfer across the lungs (VN2), has been examined in 8 resting subjects, and a study made of the effect of diet upon this relationship.	Nitrogen	88-96	telomeric repeat binding factor 1	Homo sapiens	73-77
168122-3	1975	Parietal-mucous neck cell cyclic AMP levels (3.3,0.11 means, expressed as picomoles per mg of wet weight and picomoles per mug of protein-nitrogen, respectively) were the highest in any region.	Nitrogen	138-146	transmembrane serine protease 5	Rattus norvegicus	33-36
4859329-1	1974	The role of leghemoglobin in nitrogen fixation by bacteroids isolated from soybean root nodules.	Nitrogen	29-37	leghemoglobin A	Glycine max	12-25
4851630-0	1974	Effect of different human growth hormone preparations on nitrogen retention in hypopituitary children.	Nitrogen	57-65	growth hormone 1	Homo sapiens	26-40
806018-6	1975	The presumed mechanism for improved nitrogen sparing is a decrease in serum glucose and insulin levels, allowing greater endogenous fat mobilization and utilization, thus sparing lean body mass.	Nitrogen	36-44	insulin	Homo sapiens	88-95
1133822-1	1975	Norepinephrine N-methyltransferase (NMT) from rabbit adrenal glands was inhibited by benzylamine and phenethylamine analogs in which the nitrogen was replaced by an amidino or guanidino group.	Nitrogen	137-145	N-myristoyltransferase 1	Homo sapiens	36-39
1116950-5	1975	Subtraction of the nitrogen values from the carbon monoxide values, after allowing for an absorption shift, gives the absolute spectrum of cytochrome P450.	Nitrogen	19-27	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	139-154
16095000-3	1975	The maintenance of the [URE3] determinant seems controlled by the product of a conventional nuclear gene (ure2) which is itself involved in nitrogen metabolism.	Nitrogen	140-148	glutathione peroxidase	Saccharomyces cerevisiae S288C	106-110
4412350-8	1974	Feeding burn patients or administering glucose and insulin improved nitrogen retention and altered substrate flow but did not significantly reduce urinary catecholamines or metabolic rate.	Nitrogen	68-76	insulin	Homo sapiens	51-58
4742308-0	1973	[Effect of albumin transfusion on nitrogen metabolic indices in protein insufficiency].	Nitrogen	34-42	albumin	Homo sapiens	11-18
4591987-0	1974	Nitrogen metabolism in growth hormone-deficient children receiving oxandrolone and human growth hormone.	Nitrogen	0-8	growth hormone 1	Homo sapiens	23-37
4591987-0	1974	Nitrogen metabolism in growth hormone-deficient children receiving oxandrolone and human growth hormone.	Nitrogen	0-8	growth hormone 1	Homo sapiens	89-103
24458814-2	1973	Furthermore, the pH-dependences of NO 3 (-) and NO 2 (-) uptake correspond to the pH-optima known for the reductases.Phosphate uptake is enhanced by NO 3 (-) and NO 2 (-) in N2.	Nitrogen	174-176	NBL1, DAN family BMP antagonist	Homo sapiens	35-39
4700485-13	1973	These observations indicate a role of GH in the continuing regulation of nitrogen and mineral metabolism in addition to its function as a growth-promoting hormone.	Nitrogen	73-81	growth hormone 1	Homo sapiens	38-40
4122821-0	1973	The role of cytochrome P-450 in N-hydroxylation of 2-acetylaminofluorene.	Nitrogen	32-33	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	12-28
24458814-2	1973	Furthermore, the pH-dependences of NO 3 (-) and NO 2 (-) uptake correspond to the pH-optima known for the reductases.Phosphate uptake is enhanced by NO 3 (-) and NO 2 (-) in N2.	Nitrogen	174-176	NBL1, DAN family BMP antagonist	Homo sapiens	149-153
24458814-1	1973	The pH-dependence of NO 3 (-) and NO 2 (-) uptake is different from that of phosphate uptake, but similar to that of sulfate uptake, with optima between pH 7.4 and 8.2 and smaller peaks at higher H(+)-concentration.Since the ATP-level is not affected by addition of ions and since phosphate uptake is not depressed by NO 3 (-) , the inhibition of phosphate uptake by K(+) reported in former papers cannot be explained by competition for the available energy(ATP) at the site of uptake.NO 3 (-) uptake is strongly dependent on the activity of the NO 3 (-) reducting system, as can be seen from the inhibition of NO 3 (-) uptake in light by N2 compared with that in air.	Nitrogen	639-641	NBL1, DAN family BMP antagonist	Homo sapiens	21-25
4580550-0	1972	[Formation of L-asparaginase in microorganisms depending on the nitrogen source].	Nitrogen	64-72	asparaginase and isoaspartyl peptidase 1	Homo sapiens	14-28
4345369-0	1972	[Enzymatic degradation of N-modified analogs of angiotensin II by human blood plasma].	Nitrogen	26-27	angiotensinogen	Homo sapiens	48-62
5077291-0	1972	[Nitrogen and phosphorus metabolism of helminthosporium sativum P K et B].	Nitrogen	1-9	endothelin receptor type B	Homo sapiens	68-72
5519790-0	1970	[Survival time after administration of catalase in dogs breathing pure nitrogen and at the same time perfused with perhydrol].	Nitrogen	71-79	catalase	Canis lupus familiaris	39-47
5355340-8	1969	Elevation of forearm insulin in eight subjects from postabsorptive (12 muU/ml) to high physiologic levels (157 muU/ml) in addition to stimulating muscle glucose uptake blocked muscle alpha amino nitrogen release by 74%.	Nitrogen	195-203	insulin	Homo sapiens	21-28
4226961-6	1967	This mode of oxidation appears to be unique to substrates with a positively charged quaternary nitrogen; the hydroxylation of other nonaldehydic heterocyclic substrates for the human enzyme is sensitive to conventional aldehyde oxidase inhibitors.	Nitrogen	95-103	aldehyde oxidase 1	Homo sapiens	219-235
5775348-0	1969	Effect of methallibure (ICI 33,828) on the nitrogen retention and growth induced by ovine growth hormone.	Nitrogen	43-51	growth hormone 1	Homo sapiens	90-104
19873643-4	1969	Two classes of sites on AChE molecule account for the binding of these quaternary nitrogen containing compounds: (1) the anionic site of the active center and (2) noncatalytic "peripheral anionic centers" located outside the active center.	Nitrogen	82-90	acetylcholinesterase (Cartwright blood group)	Homo sapiens	24-28
6025368-0	1967	Growth hormone-induced nitrogen retention in children of short stature.	Nitrogen	23-31	growth hormone 1	Homo sapiens	0-14
5849491-0	1965	Growth hormone effect on the role of fat in nitrogen metabolism.	Nitrogen	44-52	growth hormone 1	Homo sapiens	0-14
5592544-0	1967	[Experiences with the prader nitrogen retention test with human pituitary growth hormone (HGH) in various types of dwarism].	Nitrogen	29-37	growth hormone 1	Homo sapiens	64-88
13941712-0	1962	[Behavior of the blood level of urea nitrogen after the administration of human somatotropin].	Nitrogen	37-45	growth hormone 1	Homo sapiens	80-92
4959191-0	1965	[The effect of chymotrypsin hydrolysates of bull and hog growth hormone on the content of urea, total and residual nitrogen in the blood of monkeys].	Nitrogen	115-123	growth hormone 1	Homo sapiens	57-71
17773778-2	1965	The distribution of n-alkanes shows two maxima, one at about C(18) to C(19) and the other at about C(22) with a minimum occurring at C(20) to C(21).	Nitrogen	15-16	Bardet-Biedl syndrome 9	Homo sapiens	61-66
17773778-2	1965	The distribution of n-alkanes shows two maxima, one at about C(18) to C(19) and the other at about C(22) with a minimum occurring at C(20) to C(21).	Nitrogen	15-16	TBL1X/Y related 1	Homo sapiens	142-147
14098449-0	1963	EFFECT OF NITROGEN MUSTARD ON ERYTHROCYTE ACETYLCHOLINESTERASE.	Nitrogen	10-18	acetylcholinesterase (Cartwright blood group)	Homo sapiens	42-62
14014314-0	1962	[On the formation of N-peptide bonds on the interaction of O-(benzoylphenyl-alanyl-1-C-14)-N-benzoylserine with insulin].	Nitrogen	21-22	insulin	Homo sapiens	112-119
16656636-4	1967	Increases in ribonuclease often parallel or precede increases in the soluble nitrogen content.	Nitrogen	77-85	intracellular ribonuclease LX	Solanum lycopersicum	13-25
13997530-0	1963	Effects of growth hormone on metabolism of nitrogen from several amino acids and ammonia.	Nitrogen	43-51	growth hormone 1	Homo sapiens	11-25
13645689-0	1959	Effect of human growth hormone on UFA and plasma amino acid nitrogen in man.	Nitrogen	60-68	growth hormone 1	Homo sapiens	16-30
13749796-2	1961	Ash and mineral content in the dry substance - nitrogen, phosphorus and sulfur in the lipid-and water-free residue].	Nitrogen	47-55	arylsulfatase family member H	Homo sapiens	0-3
13342234-0	1956	[Anti-cortisol effect of vitamin B12 in nitrogen balance].	Nitrogen	40-48	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	33-36
13638281-0	1959	[Effect of ACTH on certain aspects of fat-carbohydrate and nitrogen metabolism in dogs].	Nitrogen	59-67	proopiomelanocortin	Canis lupus familiaris	11-15
13069525-0	1953	The nitrogen terminal end-groups of hypophyseal growth hormone.	Nitrogen	4-12	growth hormone 1	Homo sapiens	48-62
13391420-0	1956	The influence of growth hormone on the nitrogen balance of the severely burned.	Nitrogen	39-47	growth hormone 1	Homo sapiens	17-31
13081140-0	1953	Carbohydrate and nitrogen distribution during the activation of purified prothrombin in sodium citrate solution.	Nitrogen	17-25	coagulation factor II, thrombin	Homo sapiens	73-84
13030731-0	1953	Conjugation of benzoic and phenylacetic acids during nitrogen storage induced with growth hormone or testosterone propionate.	Nitrogen	53-61	growth hormone 1	Homo sapiens	83-97
14938438-0	1952	A metabolic study of a diabetic patient: the effect of variations in the dosage of insulin upon adrenal cortical activity and upon water, electrolyte and nitrogen excretion.	Nitrogen	154-162	insulin	Homo sapiens	83-90
14900622-0	1951	[Determination of ACTH in nitrogen mustard therapy].	Nitrogen	26-34	proopiomelanocortin	Homo sapiens	18-22
14928929-0	1952	[Nitrogen mustards in bronchial asthma; relation with ACTH, cortisone and general adaptation syndrome].	Nitrogen	1-9	proopiomelanocortin	Homo sapiens	54-58
14939685-0	1952	[Relations in the mechanism of nitrogen mustard and ACTH].	Nitrogen	31-39	proopiomelanocortin	Homo sapiens	52-56
14857186-0	1951	Relation of purifies pituitary growth hormone and insulin in regulation of nitrogen balance.	Nitrogen	75-83	insulin	Homo sapiens	50-57
15436778-0	1950	Salutary action of ACTH in a case of periarteritis nodosa: the effective dose as measured by nitrogen and electrolyte balances.	Nitrogen	93-101	proopiomelanocortin	Homo sapiens	19-23
14782746-0	1951	Insulin-resistant diabetes precipitated by cortisone and reversed by nitrogen mustard.	Nitrogen	69-77	insulin	Homo sapiens	0-7
18914208-0	1948	The effect of dietary protein content upon the nitrogen retention and weight gain produced by the hypophyseal growth hormone.	Nitrogen	47-55	growth hormone 1	Homo sapiens	110-124
15422037-0	1950	Failure of hypophyseal growth hormone to produce nitrogen storage in a girl with hypophyseal dwarfism.	Nitrogen	49-57	growth hormone 1	Homo sapiens	23-37
15411907-0	1950	The antidiabetic action of insulin on nitrogen metabolism.	Nitrogen	38-46	insulin	Homo sapiens	27-34
18939193-0	1948	Unpredictable effects of growth hormone preparations on nitrogen storage.	Nitrogen	56-64	growth hormone 1	Homo sapiens	25-39
33667803-5	2021	Theoretical and experimental results suggested that nitrogen (N) vacancies modulated electric structure to build Z-scheme-charge-transfer platform for rapid reduction of Ni(III) and Co(III), thereby accelerating PMS activation for remarkable removal of emerging pollutants.	Nitrogen	52-60	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	173-176
16746199-0	1936	Synthesis of peptides containing cystine and glutamine, with remarks on their possible bearing on the structure of insulin and a note on the amide nitrogen of insulin.	Nitrogen	147-155	insulin	Homo sapiens	159-166
33609864-9	2021	The adsorption mechanism of Pb(II) on the adsorbent is mainly through the chelation of Pb(II) with N and S atoms.	Nitrogen	99-100	submaxillary gland androgen regulated protein 3B	Homo sapiens	28-34
33609864-9	2021	The adsorption mechanism of Pb(II) on the adsorbent is mainly through the chelation of Pb(II) with N and S atoms.	Nitrogen	99-100	submaxillary gland androgen regulated protein 3B	Homo sapiens	87-93
33831757-7	2021	In order to mitigate climate change and sustain food security, RR combined with paddy-upland rotation, nitrogen fertilizer input rates of 240-360 kg ha-1, and neutral soil (pH 6.5-7.5) could decrease GWP at per unit of crop yield, which ultimately leads to a lower effect on GHGI and a higher crop production efficiency.	Nitrogen	103-111	Rho GTPase activating protein 45	Homo sapiens	149-153
33667803-5	2021	Theoretical and experimental results suggested that nitrogen (N) vacancies modulated electric structure to build Z-scheme-charge-transfer platform for rapid reduction of Ni(III) and Co(III), thereby accelerating PMS activation for remarkable removal of emerging pollutants.	Nitrogen	52-60	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	182-189
33667803-5	2021	Theoretical and experimental results suggested that nitrogen (N) vacancies modulated electric structure to build Z-scheme-charge-transfer platform for rapid reduction of Ni(III) and Co(III), thereby accelerating PMS activation for remarkable removal of emerging pollutants.	Nitrogen	62-63	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	173-176
33667803-5	2021	Theoretical and experimental results suggested that nitrogen (N) vacancies modulated electric structure to build Z-scheme-charge-transfer platform for rapid reduction of Ni(III) and Co(III), thereby accelerating PMS activation for remarkable removal of emerging pollutants.	Nitrogen	62-63	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	182-189
33494889-8	2021	The CRISPR/Cas9-mediated genome modification method was used to validate the involvement of GCN1 in the yeast strain nitrogen needs.	Nitrogen	117-125	Gcn1p	Saccharomyces cerevisiae S288C	92-96
33949517-2	2021	The process involves a Csp2-N bond cleavage of anilines driven by dearomatization and a Csp3-N bond cleavage of glycine-15N driven by aromatization.	Nitrogen	28-29	regulator of calcineurin 2	Homo sapiens	23-27
33840589-9	2021	IL-6 and IL-10 were closely associated with white blood cells, neutrophils, T lymphocyte subsets, D-D dimer, blood urea nitrogen, complement C1q, procalcitonin C-reactive protein.	Nitrogen	120-128	interleukin 6	Homo sapiens	0-4
33894429-10	2021	Computational studies showed that H-bond formation between the nitrogen atom in pyrazolo[4,3-D] pyrimidine moiety with Gln817 and creating a hydrophobic cavity result in the stability of the alkyl group in the PDE5A active site.	Nitrogen	63-71	phosphodiesterase 5A	Homo sapiens	210-215
33494889-9	2021	However, the allele swapping of gene GCN1 from low nitrogen-demanding strains to high nitrogen-demanding strains did not significantly influence the fermentation rate.	Nitrogen	51-59	Gcn1p	Saccharomyces cerevisiae S288C	37-41
34037272-1	2021	Serum haptoglobin (Hp), a highly sialylated biomolecule with four N-glycosylation sites, is a positive acute-phase response glycoprotein that acts as an immunomodulator.	Nitrogen	66-67	haptoglobin	Homo sapiens	6-17
34050740-4	2021	Unlike other nlp single mutants, nlp2 and nlp7 single mutants showed a reduction in shoot fresh weight when grown in the presence of nitrate as the sole nitrogen source, indicating that NLP2, like NLP7, plays a major role in vegetative growth.	Nitrogen	153-161	Plant regulator RWP-RK family protein	Arabidopsis thaliana	33-37
34050740-4	2021	Unlike other nlp single mutants, nlp2 and nlp7 single mutants showed a reduction in shoot fresh weight when grown in the presence of nitrate as the sole nitrogen source, indicating that NLP2, like NLP7, plays a major role in vegetative growth.	Nitrogen	153-161	Plant regulator RWP-RK family protein	Arabidopsis thaliana	186-190
33960375-8	2021	D560N/R468K MBD4 bound to T:G mismatched DNA shows that the side chain amine moiety of the Lys stabilizes the flipped-out thymine by a water-mediated phosphate pinching, while the backbone carbonyl oxygen of the Lys engages in hydrogen bonds with N2 of the estranged guanine.	Nitrogen	247-249	methyl-CpG binding domain 4, DNA glycosylase	Homo sapiens	12-16
34015428-9	2021	In conclusion, TLR-activated microglia can induce different levels of neuronal network dysfunction, in which severe dysfunction is mainly caused by reactive oxygen and nitrogen species rather than proinflammatory cytokines.	Nitrogen	168-176	toll-like receptor 2	Rattus norvegicus	15-18
34014949-4	2021	We measured the responses of soil microbial biomass C and N; on soil beta-1,4-glucosidase (BG) and beta-1,4-N-acetylglucosaminidase (NAG) activity; and soil microflora characteristics to N additions gradient with 0 (control), 5 (N5), 10 (N10), and 15 (N15) g N m-2 yr-1.	Nitrogen	58-59	N-acetyl-alpha-glucosaminidase	Homo sapiens	133-136
34014949-7	2021	However, N addition increased BG activity in the N5 and N10 additions in the sandy grassland, and in the N5, N10, and N15 additions in the semi-fixed sandy land.	Nitrogen	9-10	nuclear receptor subfamily 4 group A member 1	Homo sapiens	56-59
34014949-7	2021	However, N addition increased BG activity in the N5 and N10 additions in the sandy grassland, and in the N5, N10, and N15 additions in the semi-fixed sandy land.	Nitrogen	9-10	nuclear receptor subfamily 4 group A member 1	Homo sapiens	109-112
34019934-5	2021	The activation of AGEs-mediated RAGE could evoke nicotinamide adenine dinucleotide phosphate oxidase-induced reactive oxygen and nitrogen species production and subsequently give rise to oxidative stress in DKD and ageing kidney.	Nitrogen	129-137	dual oxidase 2	Homo sapiens	49-100
34002314-1	2021	In this work, aminotriazole-modified microcrystalline cellulose microsphere (3-ATAR) containing an abundant nitrogen content as promising adsorbent was prepared via a radiation grafting method for the selective recovery ReO4- in the presence of UO22+ in acidic solution.	Nitrogen	108-116	TNF receptor superfamily member 14	Homo sapiens	79-83
34051498-8	2021	The regression equations showed that the maximum yield was 8294 kg ha-1 for CUF at the application rate of 312 kg N ha-1 while it was 9890 kg ha-1 for CRF at the application rate of 286 kg N ha-1.	Nitrogen	114-115	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	67-71
33758916-3	2021	Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3.	Nitrogen	10-11	nitrate transporter 2:1	Arabidopsis thaliana	179-183
33984806-2	2021	In this study, we designed a series of novel NQO1 substrates by introducing aliphatic nitrogen-containing side chains to fit with the L-shaped pocket of NQO1 by the formation of cation-pi interactions.	Nitrogen	86-94	NAD(P)H quinone dehydrogenase 1	Homo sapiens	45-49
33984806-2	2021	In this study, we designed a series of novel NQO1 substrates by introducing aliphatic nitrogen-containing side chains to fit with the L-shaped pocket of NQO1 by the formation of cation-pi interactions.	Nitrogen	86-94	NAD(P)H quinone dehydrogenase 1	Homo sapiens	153-157
33984806-3	2021	Molecular dynamics (MD) simulation indicated that the basic N atom in the side chain of NQO1 substrates, which is prone to be protonated under physiological conditions, can form cation-pi interactions with the Phe232 and Phe236 residues of the NQO1 enzyme.	Nitrogen	60-61	NAD(P)H quinone dehydrogenase 1	Homo sapiens	88-92
33984806-3	2021	Molecular dynamics (MD) simulation indicated that the basic N atom in the side chain of NQO1 substrates, which is prone to be protonated under physiological conditions, can form cation-pi interactions with the Phe232 and Phe236 residues of the NQO1 enzyme.	Nitrogen	60-61	NAD(P)H quinone dehydrogenase 1	Homo sapiens	244-248
33561682-2	2021	The N@GQDs was functionalized with beta-cyclodextrin (beta-CD) to improve its catalytic performance towards dopamine (DA) detection.	Nitrogen	4-5	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	54-61
33561682-3	2021	The beta-CD/N@GQDs exhibited strong fluorescence at lambdaem.	Nitrogen	12-13	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	4-11
33561682-5	2021	The beta-CD/N@GQDs showed good peroxidase like activity via catalyzing the oxidation of tetramethylbenzidine (TMB) in presence of H2O2 to form blue colored product at lambdamax = 652 nm.	Nitrogen	12-13	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	4-11
33561682-8	2021	While the fluorometric detection of DA based on the "inner filter effect" of the overlapped emission spectrum of beta-CD/N@GQDs with the absorption spectrum of oxTMB, where, addition of DA reduces oxTMB to TMB and restores the fluorescence intensity of beta-CD/N@GQDs.	Nitrogen	121-122	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	113-120
33561682-8	2021	While the fluorometric detection of DA based on the "inner filter effect" of the overlapped emission spectrum of beta-CD/N@GQDs with the absorption spectrum of oxTMB, where, addition of DA reduces oxTMB to TMB and restores the fluorescence intensity of beta-CD/N@GQDs.	Nitrogen	121-122	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	253-260
33561682-8	2021	While the fluorometric detection of DA based on the "inner filter effect" of the overlapped emission spectrum of beta-CD/N@GQDs with the absorption spectrum of oxTMB, where, addition of DA reduces oxTMB to TMB and restores the fluorescence intensity of beta-CD/N@GQDs.	Nitrogen	261-262	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	113-120
33561682-8	2021	While the fluorometric detection of DA based on the "inner filter effect" of the overlapped emission spectrum of beta-CD/N@GQDs with the absorption spectrum of oxTMB, where, addition of DA reduces oxTMB to TMB and restores the fluorescence intensity of beta-CD/N@GQDs.	Nitrogen	261-262	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	253-260
33963081-0	2021	Low nitrogen conditions accelerate flowering by modulating the phosphorylation state of FLOWERING BHLH 4 in Arabidopsis.	Nitrogen	4-12	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	88-104
33963081-4	2021	Here, we identify the FLOWERING BHLH 4 (FBH4) transcription factor as a key regulator of N-responsive flowering in Arabidopsis Low N-induced early flowering is compromised in fbh quadruple mutants.	Nitrogen	29-30	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	40-44
33963081-4	2021	Here, we identify the FLOWERING BHLH 4 (FBH4) transcription factor as a key regulator of N-responsive flowering in Arabidopsis Low N-induced early flowering is compromised in fbh quadruple mutants.	Nitrogen	89-90	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	22-38
33963081-4	2021	Here, we identify the FLOWERING BHLH 4 (FBH4) transcription factor as a key regulator of N-responsive flowering in Arabidopsis Low N-induced early flowering is compromised in fbh quadruple mutants.	Nitrogen	89-90	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	40-44
33963081-5	2021	We found that FBH4 is a highly phosphorylated protein and that FBH4 phosphorylation levels decrease under low N conditions.	Nitrogen	110-111	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	14-18
33963081-5	2021	We found that FBH4 is a highly phosphorylated protein and that FBH4 phosphorylation levels decrease under low N conditions.	Nitrogen	110-111	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	63-67
33963081-7	2021	Moreover, we demonstrate that the evolutionarily conserved cellular fuel sensor SNF1-RELATED KINASE 1 (SnRK1), whose kinase activity is down-regulated under low N conditions, directly phosphorylates FBH4.	Nitrogen	81-82	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	199-203
33963081-9	2021	Together, these results reveal a mechanism by which N levels may fine-tune FBH4 nuclear localization by adjusting the phosphorylation state to modulate flowering time.	Nitrogen	52-53	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	75-79
33963081-10	2021	In addition to its role in flowering regulation, we also showed that FBH4 was involved in low N-induced up-regulation of nutrient recycling and remobilization-related gene expression.	Nitrogen	94-95	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	69-73
33890760-2	2021	Here, we report on augmenting the O2-evolving strategy based on a biomimetic, catalytic nanovehicle (named as N/P@MCC), constructed by the catalase-immobilized hollow mesoporous nanospheres by enveloping a cancer cell membrane (CCM), which acts as an efficient nanocontainer to accommodate nitrogen-doped graphene quantum dots (N-GQDs) and protoporphyrin IX (PpIX).	Nitrogen	290-298	catalase	Homo sapiens	139-147
33950377-9	2021	The relationship between the mean stand DBH and the N stock of the total forest floor was determined to have a higher correlation in maritime pine (R2 = 0.8) than stone pine (R2 = 0.4).	Nitrogen	52-53	dopamine beta-hydroxylase	Meleagris gallopavo	40-43
33831352-0	2021	Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis.	Nitrogen	8-16	target of rapamycin	Arabidopsis thaliana	50-53
33831352-2	2021	Amino acids (AAs) are key upstream signals for mammalian TOR activation, but how nitrogen-related nutrients regulate TOR signaling in plants is poorly understood.	Nitrogen	81-89	target of rapamycin	Arabidopsis thaliana	117-120
33831352-3	2021	Here, we discovered that, independent of nitrogen assimilation, nitrate and ammonium function as primary nitrogen signals to activate TOR in the Arabidopsis leaf primordium.	Nitrogen	105-113	target of rapamycin	Arabidopsis thaliana	134-137
33831352-5	2021	Interestingly, nitrate, ammonium, and glutamine all activate the small GTPase Rho-related protein from plants 2 (ROP2), and constitutively active ROP2 restores TOR activation under nitrogen-starvation conditions.	Nitrogen	181-189	target of rapamycin	Arabidopsis thaliana	160-163
33945780-0	2021	Activation of TOR signaling by diverse nitrogen signals in plants.	Nitrogen	39-47	RAR related orphan receptor C	Homo sapiens	14-17
33831352-6	2021	Our findings suggest that specific evolutionary adaptations of the nitrogen-TOR signaling pathway occurred in plant lineages, and ROP2 can integrate diverse nitrogen and hormone signals for plant TOR activation.	Nitrogen	67-75	target of rapamycin	Arabidopsis thaliana	76-79
33758916-3	2021	Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3.	Nitrogen	43-51	nitrate transporter 2:1	Arabidopsis thaliana	179-183
33831352-6	2021	Our findings suggest that specific evolutionary adaptations of the nitrogen-TOR signaling pathway occurred in plant lineages, and ROP2 can integrate diverse nitrogen and hormone signals for plant TOR activation.	Nitrogen	67-75	target of rapamycin	Arabidopsis thaliana	196-199
33831352-6	2021	Our findings suggest that specific evolutionary adaptations of the nitrogen-TOR signaling pathway occurred in plant lineages, and ROP2 can integrate diverse nitrogen and hormone signals for plant TOR activation.	Nitrogen	157-165	target of rapamycin	Arabidopsis thaliana	76-79
33831352-6	2021	Our findings suggest that specific evolutionary adaptations of the nitrogen-TOR signaling pathway occurred in plant lineages, and ROP2 can integrate diverse nitrogen and hormone signals for plant TOR activation.	Nitrogen	157-165	target of rapamycin	Arabidopsis thaliana	196-199
33945780-3	2021	demonstrate that, in plants, inorganic nitrogen and amino acids activate TOR via the GTPase ROP2 to promote cell proliferation and leaf growth in the shoot.	Nitrogen	39-47	RAR related orphan receptor C	Homo sapiens	73-76
33758916-3	2021	Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3.	Nitrogen	43-44	nitrate transporter 2:1	Arabidopsis thaliana	179-183
33471394-7	2021	N-glycoengineering was carried out to add a new glycosylation site within the hEPO sequence responsible for its EA.	Nitrogen	0-1	erythropoietin	Homo sapiens	78-82
32122715-1	2021	PURPOSE: This study aimed to determine whether the blood urea nitrogen to serum albumin (B/A) ratio is a useful prognostic factor of mortality in patients with aspiration pneumonia.	Nitrogen	62-70	albumin	Homo sapiens	80-87
33706413-11	2021	Clarifying the role of N-glycosylated GPNMB in regulating the ligand-independent activation of mutated EGFR may provide a new insight for developing novel therapeutics for NSCLC in the near future.	Nitrogen	23-24	glycoprotein nmb	Homo sapiens	38-43
33460896-7	2021	Metagenomics analysis revealed that the preferred metabolic pathway of nitrogen was from ammonium to glutamate via glutamine, and the enzymes governing this transformation were glutamine synthetase and glutamate synthetase; while in nitrate based amendment, the conversion from nitrite to ammonium was restrained by the low abundance of nitrite reductase enzyme and therefore retarded the TPH degradation rate.	Nitrogen	71-79	glutamate-ammonia ligase	Homo sapiens	177-197
33706413-11	2021	Clarifying the role of N-glycosylated GPNMB in regulating the ligand-independent activation of mutated EGFR may provide a new insight for developing novel therapeutics for NSCLC in the near future.	Nitrogen	23-24	epidermal growth factor receptor	Homo sapiens	103-107
33674271-4	2021	The N-oxidation of PQ to PN1 was mainly mediated by CYP3A4, and PN1 can rapidly reduce back to PQ via CYP/FMO enzymes.	Nitrogen	4-5	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	52-58
33674271-5	2021	In accordance with these findings, the CYP non-selective inhibitor (1-ABT) or CYP3A4 inhibitor (ketoconazole) inhibited the N-oxidation pathway in liver microsomes (>90%), and the reduction metabolism was inhibited by 1-ABT (>90%) or methimazole (~50%).	Nitrogen	124-125	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	78-84
33484031-10	2021	Overall, our results suggest that atmospherically deposited NH4 + and NO3 - is rapidly lost in the short-term (months) but thereafter securely retained within the ecosystem, with retained N becoming redistributed to plants and mineral soil from the organic soil.	Nitrogen	60-61	NBL1, DAN family BMP antagonist	Homo sapiens	70-73
33381907-2	2021	Bang-25 consists of the first 25 amino acids of the N-terminus of angiotensinogen (Aogen), with N-linked glycosylation on the 14th amino acid and a cysteine conjugated to the 18th amino acid.	Nitrogen	52-53	angiotensinogen	Homo sapiens	66-81
33376033-3	2021	Moreover, A-DROP (for classifying the severity of community-acquired pneumonia) or the blood urea nitrogen-to-serum albumin ratio (BUN/Alb), which is reported to be a predictor of mortality of community-acquired pneumonia, has not been established as an efficient prognostic factor in patients with non-HIV PcP.	Nitrogen	98-106	albumin	Homo sapiens	116-123
33376033-3	2021	Moreover, A-DROP (for classifying the severity of community-acquired pneumonia) or the blood urea nitrogen-to-serum albumin ratio (BUN/Alb), which is reported to be a predictor of mortality of community-acquired pneumonia, has not been established as an efficient prognostic factor in patients with non-HIV PcP.	Nitrogen	98-106	albumin	Homo sapiens	135-138
33381907-2	2021	Bang-25 consists of the first 25 amino acids of the N-terminus of angiotensinogen (Aogen), with N-linked glycosylation on the 14th amino acid and a cysteine conjugated to the 18th amino acid.	Nitrogen	52-53	angiotensinogen	Homo sapiens	83-88
33947960-2	2021	Trastuzumab"s target epitope is localized within the extracellular domain of the oncogenic cell surface receptor tyrosine kinase (RTK) ErbB2, which is known to undergo extensive N-linked glycosylation.	Nitrogen	178-179	erb-b2 receptor tyrosine kinase 2	Homo sapiens	135-140
33607139-8	2021	The main adsorption mechanism was the chelating and electrostatic action between N and O groups in CS-Ninhydrin and Pb(II) ions.	Nitrogen	81-82	submaxillary gland androgen regulated protein 3B	Homo sapiens	116-122
33947960-5	2021	In-depth mass spectrometry-based glycomic and glycoproteomic analysis of ErbB2"s ectodomain disclosed a site-specific glycosylation profile in GC cells, in which the ST6Gal1 sialyltransferase specifically targets ErbB2 N-glycosylation sites occurring within the receptor"s trastuzumab-binding domain.	Nitrogen	219-220	erb-b2 receptor tyrosine kinase 2	Homo sapiens	73-78
33922963-4	2021	The experiments exposed that the coupling of a nitrogen ambient with the graphene admixing triggers, in both compact and porous samples, important structural (i.e., decomposition of beta-Ca3(PO4)2 into alpha-Ca3(PO4)2 and alpha-Ca2P2O7) and morphological modifications.	Nitrogen	47-55	small nucleolar RNA, H/ACA box 3A	Homo sapiens	182-190
33924774-5	2021	Here we show that N-linked glycosylation in the ANTXR1 vWA domain is necessary for SVV attachment and entry.	Nitrogen	18-19	ANTXR cell adhesion molecule 1	Homo sapiens	48-54
33924774-9	2021	Overall, our results identified N-glycosylation in ANTXR1 as a necessary post-translational modification for establishing stable interactions with SVV.	Nitrogen	32-33	ANTXR cell adhesion molecule 1	Homo sapiens	51-57
33894774-4	2021	Here, we studied the association between matrix stiffness modulation, GSC migration and MGAT5 induced N-glycosylation in fibrillar 3D context.	Nitrogen	102-103	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	88-93
33946721-6	2021	Except for down-regulation under nitrogen starvation, the CrCUL3 gene was induced by sulfur and iron starvation.	Nitrogen	33-41	uncharacterized protein	Chlamydomonas reinhardtii	58-64
33910203-8	2021	Challenging hMPO-immunized rats with the anti-GBM serum led to more glomerular neutrophil infiltration and MPO release, and severe haematuria, heavy proteinuria, and higher blood urea nitrogen than hMPO alone.	Nitrogen	184-192	myeloperoxidase	Homo sapiens	12-16
33922963-4	2021	The experiments exposed that the coupling of a nitrogen ambient with the graphene admixing triggers, in both compact and porous samples, important structural (i.e., decomposition of beta-Ca3(PO4)2 into alpha-Ca3(PO4)2 and alpha-Ca2P2O7) and morphological modifications.	Nitrogen	47-55	small nucleolar RNA, H/ACA box 3A	Homo sapiens	202-211
33829753-3	2021	Herein, we report an effective CO2RR electrocatalyst that features Ag single-atom coordinated with three nitrogen atoms (Ag1-N3) anchored on porous concave N-doped carbon (Ag1-N3/PCNC), which is identified by X-ray absorption spectroscopy.	Nitrogen	105-113	thioredoxin domain containing 12	Homo sapiens	121-124
33884554-0	2021	Vegetation restoration and agricultural management to mitigate nitrogen pollution in the surface waters of the Dan River, China.	Nitrogen	63-71	NBL1, DAN family BMP antagonist	Homo sapiens	111-114
33935494-11	2021	Conclusion: Alendronate application partially reversed the suppression of expression of BMP2, EIF2AK3, EIF2A, ATF4 caused by liquid nitrogen.	Nitrogen	132-140	activating transcription factor 4	Rattus norvegicus	110-114
33422844-1	2021	Nitrogen losses from intensive agricultural production may end up as high nitrate (NO3-) concentrations in groundwater, with a long-term impact on groundwater quality.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	83-86
33710222-5	2021	The increase in the alkyl chain length, from ethyl, butyl, hexyl, and octyl to decyl, led to a remarkable variation in the properties of the OCDs, i.e., a reduction in nitrogen doping from 40.71 to 20.75%, a decrease in binding affinity with bovine serum albumin (BSA), and an increase in cytotoxicity.	Nitrogen	168-176	albumin	Homo sapiens	249-262
33862200-1	2021	Relatively high concentration of nitric oxide (NO) produced by inducible nitric oxide synthase (iNOS) in response to a variety of stimuli is a source of reactive nitrogen species, an important weapon of host innate immune defense.	Nitrogen	162-170	nitric oxide synthase 2	Homo sapiens	63-94
33862200-1	2021	Relatively high concentration of nitric oxide (NO) produced by inducible nitric oxide synthase (iNOS) in response to a variety of stimuli is a source of reactive nitrogen species, an important weapon of host innate immune defense.	Nitrogen	162-170	nitric oxide synthase 2	Homo sapiens	96-100
33876441-7	2021	Reducing N rate to agronomically optimized treatment (180 kg N ha-1 yr-1 ) significantly decreased N leaching by 77%, and maintained high grain yield of 8.1 Mg ha-1 .	Nitrogen	9-10	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	63-67
33882512-5	2021	For in vitro assessment, human renal epithelium HK-2 cells were cultured under serum starvation conditions or with tacrolimus.The administration of SLPI (250 mug/kg, i.p) reduced elevated plasma creatinine and blood urea nitrogen levels, tissue myeloperoxidase content, and acute tubular necrosis induced by kidney damage.	Nitrogen	221-229	secretory leukocyte peptidase inhibitor	Homo sapiens	148-152
33876441-7	2021	Reducing N rate to agronomically optimized treatment (180 kg N ha-1 yr-1 ) significantly decreased N leaching by 77%, and maintained high grain yield of 8.1 Mg ha-1 .	Nitrogen	61-62	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	63-67
33876441-7	2021	Reducing N rate to agronomically optimized treatment (180 kg N ha-1 yr-1 ) significantly decreased N leaching by 77%, and maintained high grain yield of 8.1 Mg ha-1 .	Nitrogen	61-62	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	63-67
33752328-7	2021	Finally, this strategy was successfully applied in highly sensitive profiling and reproducible quantitation of the serum alpha-2,3-sialylated N-glycome from ovarian cancer (OC) patients, where 7 of 33 detected alpha-2,3-sialylated N-glycans significantly changed in the OC group compared with healthy controls.	Nitrogen	142-143	glycoprotein hormone subunit alpha 2	Homo sapiens	121-128
33290375-10	2021	RESULTS: The plasma ccf mt-DNA levels of both ND1 and CYTC were significantly decreased in patients with CS compared with levels in controls both in total and by sex, while the plasma ccf n-DNA levels showed no significant difference.	Nitrogen	51-52	mitochondrially encoded NADH dehydrogenase 1	Homo sapiens	46-49
33953835-2	2021	Enrichment analysis of differentially expressed proteins revealed alterations in endometrial remodeling, substance metabolism (mainly lipid, nitrogen, and retinol metabolism), immunological modulation, and insulin signaling in LRP sows.	Nitrogen	141-149	LDL receptor related protein 1	Homo sapiens	227-230
33752328-7	2021	Finally, this strategy was successfully applied in highly sensitive profiling and reproducible quantitation of the serum alpha-2,3-sialylated N-glycome from ovarian cancer (OC) patients, where 7 of 33 detected alpha-2,3-sialylated N-glycans significantly changed in the OC group compared with healthy controls.	Nitrogen	142-143	glycoprotein hormone subunit alpha 2	Homo sapiens	210-217
32240040-7	2021	Loss of Tps2 leads to impaired autophagic flux and reduced ATG8 expression under nitrogen starvation.	Nitrogen	81-89	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	59-63
32240040-9	2021	Tps2 regulates nuclear translocation and activation of Rim15 kinase, a negative regulator of Ume6, by causing the dissociation of Rim15 from the 14-3-3 proteins Bmh1/2 under nitrogen starvation, suggesting that Rim15 mediates the function of Tps2 as a positive regulator of ATG8 induction.	Nitrogen	174-182	protein kinase RIM15	Saccharomyces cerevisiae S288C	55-60
32240040-9	2021	Tps2 regulates nuclear translocation and activation of Rim15 kinase, a negative regulator of Ume6, by causing the dissociation of Rim15 from the 14-3-3 proteins Bmh1/2 under nitrogen starvation, suggesting that Rim15 mediates the function of Tps2 as a positive regulator of ATG8 induction.	Nitrogen	174-182	protein kinase RIM15	Saccharomyces cerevisiae S288C	130-135
32240040-9	2021	Tps2 regulates nuclear translocation and activation of Rim15 kinase, a negative regulator of Ume6, by causing the dissociation of Rim15 from the 14-3-3 proteins Bmh1/2 under nitrogen starvation, suggesting that Rim15 mediates the function of Tps2 as a positive regulator of ATG8 induction.	Nitrogen	174-182	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	161-167
32240040-9	2021	Tps2 regulates nuclear translocation and activation of Rim15 kinase, a negative regulator of Ume6, by causing the dissociation of Rim15 from the 14-3-3 proteins Bmh1/2 under nitrogen starvation, suggesting that Rim15 mediates the function of Tps2 as a positive regulator of ATG8 induction.	Nitrogen	174-182	protein kinase RIM15	Saccharomyces cerevisiae S288C	130-135
32240040-10	2021	Furthermore, Tps2 plays a crucial role in the dephosphorylation of Ser1061 and Thr1075 residues of Rim15, which is important for controlling the dissociation of Rim15 from Bmh1/2 under nitrogen starvation.	Nitrogen	185-193	protein kinase RIM15	Saccharomyces cerevisiae S288C	99-104
32240040-10	2021	Furthermore, Tps2 plays a crucial role in the dephosphorylation of Ser1061 and Thr1075 residues of Rim15, which is important for controlling the dissociation of Rim15 from Bmh1/2 under nitrogen starvation.	Nitrogen	185-193	protein kinase RIM15	Saccharomyces cerevisiae S288C	161-166
32240040-10	2021	Furthermore, Tps2 plays a crucial role in the dephosphorylation of Ser1061 and Thr1075 residues of Rim15, which is important for controlling the dissociation of Rim15 from Bmh1/2 under nitrogen starvation.	Nitrogen	185-193	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	172-178
33127147-1	2021	In the nocturnal boundary layer, nitrate radical (NO3) has an important contribution to atmospheric chemistry through oxidation of nitrogen oxides and hydrocarbons.	Nitrogen	131-139	NBL1, DAN family BMP antagonist	Homo sapiens	50-53
33098103-7	2021	Examination of exome sequence identified the presence of one additional candidate variant of unknown significance (VUS) in the N-glycosylation pathway in Patient 2: a variant predicted to have moderate-to-high impact in ALG12.	Nitrogen	127-128	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	220-225
33791968-3	2021	Higher bioavailable nitrogen concentrations in the sediments were recorded in Coringa mangroves (36.27 +- 14.7 mug g-1) and Bhitarkanika (18.54 +- 5.9 mug g-1) mangroves in the east coast followed by Karnataka (15.51 +- 8.26 mug g-1), Goa, (10.18 +- 9.96 mug g-1) and Kerala (6.36 +- 5.05 mug g-1) mangroves in the west coast.	Nitrogen	20-28	tripartite motif containing 47	Homo sapiens	235-238
33899395-13	2021	Agricultural land use significantly affected the stoichiometry of C:N:P acquiring enzymes in soils by reducing the activity of N-degrading enzymes relative, resulting in the increases of BG:NAG and the decreases of NAG:AP.	Nitrogen	68-69	N-acetyl-alpha-glucosaminidase	Homo sapiens	190-193
33459443-12	2021	N-Exos inhibited NPCs apoptosis and attenuated IVDD in rat via activation of the AKT and autophagy pathways.	Nitrogen	0-1	AKT serine/threonine kinase 1	Rattus norvegicus	81-84
33899395-13	2021	Agricultural land use significantly affected the stoichiometry of C:N:P acquiring enzymes in soils by reducing the activity of N-degrading enzymes relative, resulting in the increases of BG:NAG and the decreases of NAG:AP.	Nitrogen	68-69	N-acetyl-alpha-glucosaminidase	Homo sapiens	215-218
33300177-5	2021	The unique association behavior is due to the presence of sp 2 -hybridized nitrogen atoms, which weakly coordinate to the hydrogen atoms of these solvents and reduce the  pi -electron density of the circulene cores.	Nitrogen	75-83	Sp2 transcription factor	Homo sapiens	58-62
33548308-6	2021	PMA biosynthesis is regulated by the transcriptional activator Crz1 from Ca2+ signaling pathway, the GATA-type transcription factor Gat1 from nitrogen catabolite repression and the GATA-type transcription factor NsdD.	Nitrogen	142-150	solute carrier family 6 member 1	Homo sapiens	132-136
33753324-7	2021	Moreover, the Wbp1 protein required for N-glycosylation and interacting via its di-lysine motif with the Sec27 beta"-COP subunit is mis-targeted in cex1Delta deletion mutant cells.	Nitrogen	40-41	WW domain binding protein 1	Homo sapiens	14-18
33157282-3	2021	Here, human erythropoietin fused to human IgG Fc (EPO-Fc) was co-expressed with N-acetyl-glucosaminyltransferase-IVa (GnT-IVa) by adenoviral transduction in goat mammary gland to evaluate the in vivo modification of N-glycosylation pattern in this tissue.	Nitrogen	80-81	erythropoietin	Homo sapiens	12-26
33755986-3	2021	Additional N, applied as urea, led to decreases in delta15 N of soil NO3 - (delta15 Nnitrate , from 3.0 to 0.4%) and increases in delta15 N of soil NH4 + (delta15 Nammonium , from -1.3 to 11%) and dissolved organic N (delta15 NDON , from 8.5 to 15%) that reflected increased net nitrification rates, a possible increase in NH3 volatilization, and greater availability of the three N forms.	Nitrogen	11-12	NBL1, DAN family BMP antagonist	Homo sapiens	69-72
33755986-3	2021	Additional N, applied as urea, led to decreases in delta15 N of soil NO3 - (delta15 Nnitrate , from 3.0 to 0.4%) and increases in delta15 N of soil NH4 + (delta15 Nammonium , from -1.3 to 11%) and dissolved organic N (delta15 NDON , from 8.5 to 15%) that reflected increased net nitrification rates, a possible increase in NH3 volatilization, and greater availability of the three N forms.	Nitrogen	59-60	NBL1, DAN family BMP antagonist	Homo sapiens	69-72
33755986-3	2021	Additional N, applied as urea, led to decreases in delta15 N of soil NO3 - (delta15 Nnitrate , from 3.0 to 0.4%) and increases in delta15 N of soil NH4 + (delta15 Nammonium , from -1.3 to 11%) and dissolved organic N (delta15 NDON , from 8.5 to 15%) that reflected increased net nitrification rates, a possible increase in NH3 volatilization, and greater availability of the three N forms.	Nitrogen	59-60	NBL1, DAN family BMP antagonist	Homo sapiens	69-72
33755986-3	2021	Additional N, applied as urea, led to decreases in delta15 N of soil NO3 - (delta15 Nnitrate , from 3.0 to 0.4%) and increases in delta15 N of soil NH4 + (delta15 Nammonium , from -1.3 to 11%) and dissolved organic N (delta15 NDON , from 8.5 to 15%) that reflected increased net nitrification rates, a possible increase in NH3 volatilization, and greater availability of the three N forms.	Nitrogen	59-60	NBL1, DAN family BMP antagonist	Homo sapiens	69-72
33755986-3	2021	Additional N, applied as urea, led to decreases in delta15 N of soil NO3 - (delta15 Nnitrate , from 3.0 to 0.4%) and increases in delta15 N of soil NH4 + (delta15 Nammonium , from -1.3 to 11%) and dissolved organic N (delta15 NDON , from 8.5 to 15%) that reflected increased net nitrification rates, a possible increase in NH3 volatilization, and greater availability of the three N forms.	Nitrogen	59-60	NBL1, DAN family BMP antagonist	Homo sapiens	69-72
33755986-5	2021	Plant delta15 N, which ranged from -1.8 to 2.1%, generally decreased with N addition, indicating a greater reliance on soil NO3 - under N-enrichment conditions.	Nitrogen	74-75	NBL1, DAN family BMP antagonist	Homo sapiens	124-127
33755986-5	2021	Plant delta15 N, which ranged from -1.8 to 2.1%, generally decreased with N addition, indicating a greater reliance on soil NO3 - under N-enrichment conditions.	Nitrogen	74-75	NBL1, DAN family BMP antagonist	Homo sapiens	124-127
33755986-6	2021	Nitrogen addition decreased delta15 N of microbial biomass N (from 14 to 2.8%), possibly due to a shift in preferential N form (DON to NO3 - ), that indicated a convergence of plant and microbial preferential N forms and an increase in plant-microbial N competition.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	135-138
33755986-6	2021	Nitrogen addition decreased delta15 N of microbial biomass N (from 14 to 2.8%), possibly due to a shift in preferential N form (DON to NO3 - ), that indicated a convergence of plant and microbial preferential N forms and an increase in plant-microbial N competition.	Nitrogen	0-1	NBL1, DAN family BMP antagonist	Homo sapiens	135-138
33889819-3	2021	In the present paper, we detailed the unique serum N-glycosylation of a CDG-candidate patient with an unexplained neurological phenotype and liver adenomatosis harboring a recurrent pathogenic HNF1alpha variant.	Nitrogen	51-52	HNF1 homeobox A	Homo sapiens	193-202
33889819-4	2021	Serum transferrin isoelectric focusing showed a surprising N-glycosylation pattern consisting on hyposialylation, as well as remarkable hypersialylation.	Nitrogen	59-60	transferrin	Homo sapiens	6-17
33707259-1	2021	Here we report that attempted preparation of low-valent CaI complexes in the form of LCa-CaL (where L is a bulky beta-diketiminate ligand) under dinitrogen (N2) atmosphere led to isolation of LCa(N2)CaL, which was characterized crystallographically.	Nitrogen	145-155	clathrin light chain A	Homo sapiens	192-195
33692125-4	2021	We identify a pathological signaling cascade whereby reactive nitrogen species cause S-nitrosylation of TDP-43 (forming SNO-TDP-43) to facilitate disulfide linkage and consequent TDP-43 aggregation.	Nitrogen	62-70	TAR DNA binding protein	Homo sapiens	104-110
33692125-4	2021	We identify a pathological signaling cascade whereby reactive nitrogen species cause S-nitrosylation of TDP-43 (forming SNO-TDP-43) to facilitate disulfide linkage and consequent TDP-43 aggregation.	Nitrogen	62-70	TAR DNA binding protein	Homo sapiens	120-130
33223238-0	2021	Nitrogen and fluorine co-doped green fluorescence carbon dots as a label-free probe for determination of cytochrome c in serum and temperature sensing.	Nitrogen	0-8	cytochrome c, somatic	Homo sapiens	105-117
33223238-2	2021	This work develops a label-free probe for Cyt c using the nitrogen and fluorine co-doped carbon dots (N, F-CDs) which were facile prepared through solvothermal method with 3, 4-difluorophenylhydrazine as precursor.	Nitrogen	58-66	cytochrome c, somatic	Homo sapiens	42-47
33213923-4	2021	The addition of biosolids materials to the thick compost cover at rates higher than 100 t ha-1 significantly reduced C:N ratio of the substrates, available phosphorus, and some of the nutrient cations, while notably increasing inorganic carbon and the potential solubility of Ni and Cu.	Nitrogen	119-120	Rho GTPase activating protein 45	Homo sapiens	90-94
33333400-7	2021	The results of nitrate isotopes indicated that NO3- mainly originated from soil N nitrogen, chemical fertilizer, and manure and sewage wastes.	Nitrogen	82-90	NBL1, DAN family BMP antagonist	Homo sapiens	47-50
33707259-1	2021	Here we report that attempted preparation of low-valent CaI complexes in the form of LCa-CaL (where L is a bulky beta-diketiminate ligand) under dinitrogen (N2) atmosphere led to isolation of LCa(N2)CaL, which was characterized crystallographically.	Nitrogen	145-155	clathrin light chain A	Homo sapiens	85-88
33707259-1	2021	Here we report that attempted preparation of low-valent CaI complexes in the form of LCa-CaL (where L is a bulky beta-diketiminate ligand) under dinitrogen (N2) atmosphere led to isolation of LCa(N2)CaL, which was characterized crystallographically.	Nitrogen	157-159	clathrin light chain A	Homo sapiens	85-88
33707259-1	2021	Here we report that attempted preparation of low-valent CaI complexes in the form of LCa-CaL (where L is a bulky beta-diketiminate ligand) under dinitrogen (N2) atmosphere led to isolation of LCa(N2)CaL, which was characterized crystallographically.	Nitrogen	196-198	clathrin light chain A	Homo sapiens	85-88
33707259-1	2021	Here we report that attempted preparation of low-valent CaI complexes in the form of LCa-CaL (where L is a bulky beta-diketiminate ligand) under dinitrogen (N2) atmosphere led to isolation of LCa(N2)CaL, which was characterized crystallographically.	Nitrogen	196-198	clathrin light chain A	Homo sapiens	192-195
33678121-9	2021	Efficient transfer to phagophores depends on the sorting nexin heterodimer Snx4/Atg24-Atg20, which binds to Atg17, and relocates to the perinucleus following nitrogen starvation.	Nitrogen	158-166	sorting nexin 4	Homo sapiens	75-79
33369135-1	2021	ATP6V0A2-related cutis laxa, also known as autosomal recessive cutis laxa type 2A (ARCL2A), is a subtype of hereditary cutis laxa originally characterized by skin, skeletal, and neurological involvement, and a combined defect of N-glycosylation and O-glycosylation.	Nitrogen	229-230	ATPase H+ transporting V0 subunit a2	Homo sapiens	0-8
33615795-3	2021	The heteroatom moieties in 2-DMAP (sp2 and sp3 nitrogen) and PAS (sp2 nitrogen and sulfonate ion) can coordinate to the ITO surface and decrease the ITO work function by the induced surface dipoles.	Nitrogen	47-55	Sp2 transcription factor	Homo sapiens	35-38
33615795-3	2021	The heteroatom moieties in 2-DMAP (sp2 and sp3 nitrogen) and PAS (sp2 nitrogen and sulfonate ion) can coordinate to the ITO surface and decrease the ITO work function by the induced surface dipoles.	Nitrogen	47-55	Sp3 transcription factor	Homo sapiens	43-46
33615795-3	2021	The heteroatom moieties in 2-DMAP (sp2 and sp3 nitrogen) and PAS (sp2 nitrogen and sulfonate ion) can coordinate to the ITO surface and decrease the ITO work function by the induced surface dipoles.	Nitrogen	47-55	Sp2 transcription factor	Homo sapiens	66-69
33615795-3	2021	The heteroatom moieties in 2-DMAP (sp2 and sp3 nitrogen) and PAS (sp2 nitrogen and sulfonate ion) can coordinate to the ITO surface and decrease the ITO work function by the induced surface dipoles.	Nitrogen	70-78	Sp2 transcription factor	Homo sapiens	35-38
33615795-3	2021	The heteroatom moieties in 2-DMAP (sp2 and sp3 nitrogen) and PAS (sp2 nitrogen and sulfonate ion) can coordinate to the ITO surface and decrease the ITO work function by the induced surface dipoles.	Nitrogen	70-78	Sp3 transcription factor	Homo sapiens	43-46
33615795-3	2021	The heteroatom moieties in 2-DMAP (sp2 and sp3 nitrogen) and PAS (sp2 nitrogen and sulfonate ion) can coordinate to the ITO surface and decrease the ITO work function by the induced surface dipoles.	Nitrogen	70-78	Sp2 transcription factor	Homo sapiens	66-69
33326144-0	2021	A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect.	Nitrogen	41-42	prostaglandin-endoperoxide synthase 1	Homo sapiens	27-32
33326144-0	2021	A novel genetic variant in PTGS1 affects N-glycosylation of cyclooxygenase-1 causing a dominant-negative effect.	Nitrogen	41-42	prostaglandin-endoperoxide synthase 1	Homo sapiens	60-76
33678187-2	2021	Reduced-CP broiler diets have the potential to attenuate environmental pollution from nitrogen and ammonia emissions; moreover, they have the capacity to diminish the global chicken-meat industry"s dependence on soybean meal to tangible extents.	Nitrogen	86-94	ceruloplasmin	Gallus gallus	8-10
33560857-0	2021	Site-Specific N-Linked Glycosylation Analysis of Human Carcinoembryonic Antigen by Sheathless Capillary Electrophoresis-Tandem Mass Spectrometry.	Nitrogen	14-15	CEA cell adhesion molecule 3	Homo sapiens	55-79
33560857-1	2021	With 28 potential N-glycosylation sites, human carcinoembryonic antigen (CEA) bears an extreme amount of N-linked glycosylation, and approximately 60% of its molecular mass can be attributed to its carbohydrates.	Nitrogen	18-19	CEA cell adhesion molecule 3	Homo sapiens	47-71
33560857-1	2021	With 28 potential N-glycosylation sites, human carcinoembryonic antigen (CEA) bears an extreme amount of N-linked glycosylation, and approximately 60% of its molecular mass can be attributed to its carbohydrates.	Nitrogen	18-19	CEA cell adhesion molecule 3	Homo sapiens	73-76
33560857-1	2021	With 28 potential N-glycosylation sites, human carcinoembryonic antigen (CEA) bears an extreme amount of N-linked glycosylation, and approximately 60% of its molecular mass can be attributed to its carbohydrates.	Nitrogen	105-106	CEA cell adhesion molecule 3	Homo sapiens	47-71
33560857-1	2021	With 28 potential N-glycosylation sites, human carcinoembryonic antigen (CEA) bears an extreme amount of N-linked glycosylation, and approximately 60% of its molecular mass can be attributed to its carbohydrates.	Nitrogen	105-106	CEA cell adhesion molecule 3	Homo sapiens	73-76
33560857-4	2021	The present study investigated CEA samples purified from human colon carcinoma and human liver metastases and enabled the characterization of 21 out of 28 potential N-glycosylation sites with respect to their occupancy.	Nitrogen	165-166	CEA cell adhesion molecule 3	Homo sapiens	31-34
33533759-3	2021	In both the complexes, the CoII center has a distorted octahedral geometry with a CoN6 coordination environment, formed by four equatorial N atoms from the neutral ligand and two NCS- at the axial positions.	Nitrogen	84-85	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	27-31
33369135-1	2021	ATP6V0A2-related cutis laxa, also known as autosomal recessive cutis laxa type 2A (ARCL2A), is a subtype of hereditary cutis laxa originally characterized by skin, skeletal, and neurological involvement, and a combined defect of N-glycosylation and O-glycosylation.	Nitrogen	229-230	ATPase H+ transporting V0 subunit a2	Homo sapiens	43-81
33369135-1	2021	ATP6V0A2-related cutis laxa, also known as autosomal recessive cutis laxa type 2A (ARCL2A), is a subtype of hereditary cutis laxa originally characterized by skin, skeletal, and neurological involvement, and a combined defect of N-glycosylation and O-glycosylation.	Nitrogen	229-230	ATPase H+ transporting V0 subunit a2	Homo sapiens	83-89
33387711-5	2021	The high Pb(II) adsorbing ability was attributed to the high contents of N- and O-containing functional groups of APBC.	Nitrogen	73-74	submaxillary gland androgen regulated protein 3B	Homo sapiens	9-15
33398418-6	2021	While subacute CdCl2 exposure induced kidney injury in a dose-dependent manner, after the higher Cd dosage exposure, Nrf2-KO mice showed elevated blood urea nitrogen (BUN) and urinary neutrophil gelatinase-associated lipocalin (NGAL) levels compared to control.	Nitrogen	157-165	nuclear factor, erythroid derived 2, like 2	Mus musculus	117-121
33370472-7	2021	GA in turn destabilized and degraded ROR1 protein in a dose- and time-dependent manner through ubiquitin/proteasome pathway, resulting in a significant suppression of cell proliferation in lung adenocarcinoma cell lines, for which the kinase domain of ROR1, but not its kinase activity or N-glycosylation, was required.	Nitrogen	289-290	receptor tyrosine kinase like orphan receptor 1	Homo sapiens	37-41
33515919-5	2021	In the first step, the N-glycosyltransferase from Actinobacillus pleuropneumoniae (ApNGT) is co-expressed for in vivo transfer of a glucose residue to IFNalpha at an NX(S/T) N-glycosylation sequon.	Nitrogen	23-24	interferon alpha 1	Homo sapiens	151-159
33515919-8	2021	The N-glycosylated IFNalpha product was found to be biologically active and displayed significantly improved proteolytic stability.	Nitrogen	4-5	interferon alpha 1	Homo sapiens	19-27
33370472-7	2021	GA in turn destabilized and degraded ROR1 protein in a dose- and time-dependent manner through ubiquitin/proteasome pathway, resulting in a significant suppression of cell proliferation in lung adenocarcinoma cell lines, for which the kinase domain of ROR1, but not its kinase activity or N-glycosylation, was required.	Nitrogen	289-290	receptor tyrosine kinase like orphan receptor 1	Homo sapiens	252-256
33752499-7	2021	PEBP4 had higher sensitivity for diagnosis of CKD than common indexes including blood urea nitrogen, creatinine and C-reactive protein.	Nitrogen	91-99	phosphatidylethanolamine binding protein 4	Homo sapiens	0-5
33501714-6	2021	In overexpression experiments in a cell line, DSCAML1C729R lost its mature N-glycosylation, while DSCAML1K2108Nfs*37 was abnormally degraded via proteasome-dependent protein degradation.	Nitrogen	75-76	DS cell adhesion molecule like 1	Homo sapiens	46-53
32961588-1	2021	Large-scale single-center study of slush nitrogen (SN2 ) vitrified-warmed blastocysts.	Nitrogen	41-49	solute carrier family 38 member 5	Homo sapiens	51-54
33686225-6	2021	Collectively, our results identify CEPH as a crucial enzyme in the N-starvation-dependent activation of NRT2.1 and provide molecular and mechanistic insights into how plants regulate high-affinity nitrate uptake at the post-translational level in response to the N environment.	Nitrogen	67-68	nitrate transporter 2:1	Arabidopsis thaliana	104-110
33686225-1	2021	The nitrate transporter NRT2.1, which plays a central role in high-affinity nitrate uptake in roots, is activated at the post-translational level in response to nitrogen (N) starvation1,2.	Nitrogen	161-169	nitrate transporter 2:1	Arabidopsis thaliana	24-28
33411213-4	2021	The R/R ratio, assessed as a combination of the paraoxonase 1 (PON1) gene, PON1 enzymatic activity, and early life time trauma (ELT), predicted the high-density lipoprotein cholesterol - paraoxonase 1 complex (HDL-PON1), reactive oxygen and nitrogen species (RONS), nitro-oxidative stress toxicity (NOSTOX), staging (number of depression and hypomanic episodes and suicidal attempts), and phenome (the Hamilton Depression and Anxiety scores and the Clinical Global Impression; current suicidal ideation; quality of life and disability measurements) scores.	Nitrogen	241-249	paraoxonase 1	Homo sapiens	187-200
33658826-13	2021	Plasma levels of blood urea nitrogen, creatinine, indoxyl sulfate, IL-1beta and renal tubular injury were increased in mice after renal I/R and were decreased by AST-120 treatment.	Nitrogen	28-36	solute carrier family 17 member 5	Homo sapiens	162-165
31552791-3	2021	The N-terminus of human LRRK2 consists of armadillo repeat motifs (ARMs) followed by ankyrin repeats (ANKs).	Nitrogen	4-5	leucine rich repeat kinase 2	Homo sapiens	24-29
33316534-5	2021	UN treatments significantly increased the activity of beta-1,4-glucosidase (BG) but reduced the activities of beta-1,4-N-acetylglucosaminidase (NAG), polyphenol oxidase (PPO), and peroxidase (PER).	Nitrogen	1-2	N-acetyl-alpha-glucosaminidase	Homo sapiens	144-147
33316534-5	2021	UN treatments significantly increased the activity of beta-1,4-glucosidase (BG) but reduced the activities of beta-1,4-N-acetylglucosaminidase (NAG), polyphenol oxidase (PPO), and peroxidase (PER).	Nitrogen	1-2	protoporphyrinogen oxidase	Homo sapiens	150-168
33316534-5	2021	UN treatments significantly increased the activity of beta-1,4-glucosidase (BG) but reduced the activities of beta-1,4-N-acetylglucosaminidase (NAG), polyphenol oxidase (PPO), and peroxidase (PER).	Nitrogen	1-2	protoporphyrinogen oxidase	Homo sapiens	170-173
33379006-1	2021	To promote the development of molecular imprinting technique in the separation and analysis of protein, novel bovine serum albumin (BSA) surface imprinted nitrogen-doped magnetic carbon nanotubes (N-MCNTs@MIPs) are developed by this paper.	Nitrogen	155-163	albumin	Homo sapiens	117-130
32713352-7	2021	Blood n-3 LCPUFA was inversely associated with triacylglycerol and insulin in PPARG2 minor allele carriers and positively with LDL cholesterol in major allele homozygotes (Pn-3LCPUFAxrs180182<0.01).	Nitrogen	6-7	insulin	Homo sapiens	67-74
32713352-7	2021	Blood n-3 LCPUFA was inversely associated with triacylglycerol and insulin in PPARG2 minor allele carriers and positively with LDL cholesterol in major allele homozygotes (Pn-3LCPUFAxrs180182<0.01).	Nitrogen	6-7	peroxisome proliferator activated receptor gamma	Homo sapiens	78-84
32077934-10	2021	CONCLUSIONS: These results suggest that efficient N-terminus inter-subunit communication mediated by the beta8-beta9 loop may constitute a primary regulatory mechanism for both RyR2 channel activation and suppression.	Nitrogen	2-3	ryanodine receptor 2	Homo sapiens	177-181
32077934-3	2021	METHODS AND RESULTS: We use mutational investigations combined with biochemical assays to identify the peptide sequence bridging the beta8 with beta9 strand as the primary determinant mediating RyR2 N-terminus self-association.	Nitrogen	9-10	ryanodine receptor 2	Homo sapiens	194-198
32077934-5	2021	We also show that the RyR2 N-terminus domain interacts with the C-terminal channel pore region in a Ca2+-independent manner.	Nitrogen	27-28	ryanodine receptor 2	Homo sapiens	22-26
33708398-2	2021	Nitro-sonium nitrate (NO+NO3 -), known for this property, has attracted a large interest in recent decades and was reported to be synthesized at high pressure and high temperature from a variety of nitro-gen-oxygen precursors, such as N2O4, N2O and N2-O2 mixtures.	Nitrogen	198-207	NBL1, DAN family BMP antagonist	Homo sapiens	25-28
33459307-3	2021	Herein, by the rational selection of an uncoordinated tertiary nitrogen based tricarboxylic ligand (tris[(4-carboxyl)-phenylduryl]amine, H3TCBPA), a new three-dimensional calcium-based metal-organic framework (MOF), Ca3(TCBPA)2(DMA)2(H2O)2 (1, where TCBPA = ionized tris[(4-carboxyl)-phenylduryl]amine and DMA = N,N-dimethylacetamide), possessing accessible dual catalytic sites, Lewis-basic N and Lewis-acidic Ca, has been designed and constructed by a one-pot solvothermal reaction.	Nitrogen	63-71	carbonic anhydrase 3	Homo sapiens	216-227
33732812-0	2021	Tracing Nitrogen Metabolism in Mouse Tissues with Gas Chromatography-Mass Spectrometry.	Nitrogen	8-16	gastrin	Mus musculus	50-53
33732812-3	2021	Both nuclear magnetic resonance spectroscopy and mass spectrometry including gas chromatography-mass spectrometry (GC MS) and liquid chromatography (LC MS) have been used to measure nitrogen metabolism.	Nitrogen	182-190	gastrin	Mus musculus	77-80
33671258-7	2021	The number of CD8+ T cells infiltrating the abscopal tumor and tumor-specific interferon-gamma (IFN-gamma)-producing spleen cells increased in the liquid nitrogen-treated group compared with those in the excision group, with no significant difference.	Nitrogen	154-162	interferon gamma	Mus musculus	78-94
33671258-7	2021	The number of CD8+ T cells infiltrating the abscopal tumor and tumor-specific interferon-gamma (IFN-gamma)-producing spleen cells increased in the liquid nitrogen-treated group compared with those in the excision group, with no significant difference.	Nitrogen	154-162	interferon gamma	Mus musculus	96-105
33594566-6	2021	Results showed that strain AD2 removed 98.9% of nitrate-nitrogen (NO3--N) with an initial concentration about 100 mg L-1 in 48 h without nitrite-nitrogen (NO2--N) accumulation.	Nitrogen	56-64	apolipoprotein E	Homo sapiens	27-30
33594566-6	2021	Results showed that strain AD2 removed 98.9% of nitrate-nitrogen (NO3--N) with an initial concentration about 100 mg L-1 in 48 h without nitrite-nitrogen (NO2--N) accumulation.	Nitrogen	145-153	apolipoprotein E	Homo sapiens	27-30
33673381-9	2021	Neither N-linked glycosylation sites nor carboxyl terminus domain of delta-ENaC was necessary for the TNF-induced activation of whole-cell Na+ current in delta-ENaC KD of A549 cells.	Nitrogen	0-1	tumor necrosis factor	Homo sapiens	102-105
33673381-9	2021	Neither N-linked glycosylation sites nor carboxyl terminus domain of delta-ENaC was necessary for the TNF-induced activation of whole-cell Na+ current in delta-ENaC KD of A549 cells.	Nitrogen	0-1	sodium channel epithelial 1 subunit delta	Homo sapiens	154-164
33582801-0	2021	Genome-wide analysis in response to nitrogen and carbon identifies regulators for root AtNRT2 transporters.	Nitrogen	36-44	nitrate transporter 2:1	Arabidopsis thaliana	87-93
33086215-3	2021	Here we report a gold nanoparticles-hosted mesoporous nitrogen doped carbon matrix, which is prepared using bovine serum albumin (BSA) through calcination.	Nitrogen	54-62	albumin	Homo sapiens	115-128
33582801-3	2021	At the molecular level, C and N signaling pathways control gene expression of the NRT2 transporters.	Nitrogen	30-31	nitrate transporter 2:1	Arabidopsis thaliana	82-86
33309799-3	2021	Interaction of inducible nitric oxide synthase (iNOS) with Rac2 in regulating reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation and its implications in microbial killing has been reported.	Nitrogen	121-129	nitric oxide synthase 2	Homo sapiens	15-46
33613527-11	2020	Cellular immune dysregulation with EBNA-1 immunization in mCD40-LMP1 Tg mice was accompanied by enhanced splenomegaly, increased serum blood urea nitrogen (BUN) and creatinine levels, and elevated anti-dsDNA and antinuclear antibody (ANA) levels (p<0.0001 compared to mCD40 WT mice).	Nitrogen	146-154	EBNA-1	Human gammaherpesvirus 4	35-41
33309799-3	2021	Interaction of inducible nitric oxide synthase (iNOS) with Rac2 in regulating reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation and its implications in microbial killing has been reported.	Nitrogen	121-129	nitric oxide synthase 2	Homo sapiens	48-52
33309799-3	2021	Interaction of inducible nitric oxide synthase (iNOS) with Rac2 in regulating reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation and its implications in microbial killing has been reported.	Nitrogen	121-129	Rac family small GTPase 2	Homo sapiens	59-63
33376510-8	2021	Overall, the study provides novel insights into the molecular mechanism by which GnT-V regulates the chemosensitivity to oxaliplatin, which involves the modulation of the drug transporter OCT2 by N-glycosylation in CRC cells.	Nitrogen	196-197	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	81-86
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	Nitrogen	112-114	immunoglobulin heavy constant epsilon	Homo sapiens	24-27
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	Nitrogen	112-114	allergen Ara h 1, clone P17	Arachis hypogaea	36-43
33047410-4	2021	The delta15 N values are often lower in soil nitrate (NO3 - ) than in ammonium (NH4 + ) due to large isotopic fractionation during nitrification.	Nitrogen	12-13	NBL1, DAN family BMP antagonist	Homo sapiens	54-57
33451753-6	2021	Serum creatinine and urea nitrogen levels, incidence of oliguria, and histological score of tubular necrosis at 24 h after I/R were attenuated by Ang II-pretreatment.	Nitrogen	26-34	angiotensinogen	Rattus norvegicus	146-152
33047410-9	2021	RESULTS: Inconsistent with the hypothesis, leaf delta15 N values correlated positively with leaf K, Ca, and Mg, indicating higher delta15 N values of soil NO3 - than NH4 + .	Nitrogen	138-139	NBL1, DAN family BMP antagonist	Homo sapiens	155-158
33047410-10	2021	Higher delta15 N values of soil NO3 - revealed stronger denitrification than nitrification in the study regions because isotopic fractionation occurs during nitrification and denitrification.	Nitrogen	15-16	NBL1, DAN family BMP antagonist	Homo sapiens	32-35
33435544-6	2021	Coatings formed at nitrogen pressure (pN2) up to 3 Pa crystallize both in hexagonal AlN structure and the cubic CrN structure.	Nitrogen	19-27	amyloid beta precursor protein	Homo sapiens	38-41
33503969-0	2021	Absorption of Nitrogen during Pulsed Wave L-PBF of 17-4 PH Steel.	Nitrogen	14-22	PTTG1 interacting protein	Homo sapiens	44-47
33503969-1	2021	In the fabrication of 17-4 PH by laser powder bed fusion (L-PBF) the well-documented occurrence of large amounts of retained austenite can be attributed to an elevated concentration of nitrogen present in the material.	Nitrogen	185-193	PTTG1 interacting protein	Homo sapiens	60-63
33503969-4	2021	PW L-PBF samples fabricated in cover gas conditions with varying amounts of nitrogen demonstrated reduced absorption levels compared to those produced by CW L-PBF with no effects on phase composition and minimal effects on mechanical performance.	Nitrogen	76-84	PTTG1 interacting protein	Homo sapiens	5-8
33477930-4	2021	On the other hand, higher exposure times of CAPP generated in a nitrogen atmosphere significantly inhibited succinate dehydrogenase activity, but stimulated lactate and alcohol dehydrogenase activities, suggesting anoxygenic metabolism.	Nitrogen	64-72	alcohol dehydrogenase	Glycine max	157-190
33445753-8	2021	N-glycosylation of NTCP induced by culture in human serum may contribute to viral entry.	Nitrogen	0-1	solute carrier family 10 member 1	Homo sapiens	19-23
33372494-3	2021	The results showed that the activities of beta-1,4-N-acetylglucosaminidase (NAG), leucine aminopeptidase (LAP), and alkaline phosphatase (ALP) increased significantly with the increasing years of land abandonment, whereas the activity of beta-1,4-glucosidase (BG) showed the opposite change trend.	Nitrogen	51-52	N-acetyl-alpha-glucosaminidase	Homo sapiens	76-79
33499061-3	2021	The biological activity of Fet A may be affected by various modifications, including phosphorylation, O- and N-glycosylation and fatty acid binding.	Nitrogen	109-110	alpha 2-HS glycoprotein	Homo sapiens	27-32
33396131-8	2021	Treatment of RBC with NaF enhanced the generation of reactive oxygen and nitrogen species.	Nitrogen	73-81	C-X-C motif chemokine ligand 8	Homo sapiens	22-25
33523898-4	2021	Activation of ER stress or silencing of the ER chaperone BiP exacerbates or rescues the glycosylation defects, respectively, indicating that SSR3 and SSR4 enable N-glycosylation during ER stress.	Nitrogen	162-163	growth differentiation factor 10	Homo sapiens	57-60
33585533-6	2020	The between-group ESs were high for body weight (ES = 1.2, p < 0.001), small for body composition and physical function [handgrip strength (HGS)] measures (ES < 0.25), moderate to high for n-3 PUFAs and 25-hydroxyvitamin D (25-OH vitamin D) (ES range 0.64-1.37, p < 0.05 for all), and moderate for serum C-reactive protein (ES = 0.53, p = 0.12).	Nitrogen	10-12	C-reactive protein	Homo sapiens	304-322
33407494-3	2021	METHODS: PlGF was knocked down in H358 and H1975 cells by lentiviruses, which were then cultured under hypoxia (90% N2, 5%CO2 and 5%O2) for 24 h. PlGF was overexpressed in PC9 cells treated with XAV939, inhibitor of Wnt/beta-catenin signaling pathway.	Nitrogen	116-118	placental growth factor	Homo sapiens	9-13
33227824-1	2021	The calcitonin receptor (CTR) has a large extracellular domain (ECD) with multiple N-glycosylation sites.	Nitrogen	83-84	calcitonin receptor	Homo sapiens	4-23
32822943-1	2021	Nitrogen-doped porous graphene oxide (N-PGO) was synthesized, characterized, and applied as a hydrophilic nanomaterial in fabrication of polyethersulfone (PES) membrane for Reactive Red 195 dye and bovine serum albumin (BSA) protein separation.	Nitrogen	0-8	albumin	Homo sapiens	205-218
33443146-1	2021	The Ligand of Ate1 (Liat1) is a protein of unknown function that was originally discovered through its interaction with arginyl-tRNA protein transferase 1 (Ate1), a component of the Arg/N-degron pathway of protein degradation.	Nitrogen	130-131	arginyltransferase 1	Mus musculus	14-18
33443146-1	2021	The Ligand of Ate1 (Liat1) is a protein of unknown function that was originally discovered through its interaction with arginyl-tRNA protein transferase 1 (Ate1), a component of the Arg/N-degron pathway of protein degradation.	Nitrogen	130-131	arginyltransferase 1	Mus musculus	156-160
32930709-4	2021	We also demonstrate that Jagn1 deficiency in B cells results in aberrant IgG N-glycosylation leading to enhanced Fc receptor binding.	Nitrogen	77-78	jagunal homolog 1	Mus musculus	25-30
33406610-7	2021	The prepared UiO-66-NH2@IL/PIM-1 membrane exhibited outstanding gas separation behavior with large CO2 permeation of 8283.4 Barrer and high CO2/N2 selectivity of 22.5.	Nitrogen	144-146	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	27-32
32835897-5	2021	Furthermore, among IL-10 KO offspring from CPZ-treated dams, several functional subsystems, particularly nitrogen metabolism, diverged between mice that developed spontaneous colitis (CPZ-colitis) versus those that did not (CPZ-no-colitis) at a time point prior to eventual clinical outcome.	Nitrogen	105-113	interleukin 10	Mus musculus	19-24
33182116-3	2021	This system was used to degrade nitrogen contaminants, i.e. NO3- and 4-nitrophenol.	Nitrogen	32-40	NBL1, DAN family BMP antagonist	Homo sapiens	60-63
33182116-4	2021	Optimization of the reaction conditions was carried out by a treatment of inorganic nitrogen contaminant NO3- and the optimal condition of the electrochemical system was determined at U = 5.5 V, and pH = 10 with a Cl- concentration of 2000 mg L-1, and the removal efficiency of NO3- can reach up to 60.6% in 150 min.	Nitrogen	84-92	NBL1, DAN family BMP antagonist	Homo sapiens	105-108
33515429-6	2021	Inducible nitric oxide synthase (iNOS/NOS-II) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2), the major mediators of reactive nitrogen/oxygen species (RNS/ROS) production in the brain, are also upregulated along with the pro-inflammatory cytokines following neurological insult and contribute to disease progression.	Nitrogen	152-160	nitric oxide synthase 2	Homo sapiens	33-37
33227824-1	2021	The calcitonin receptor (CTR) has a large extracellular domain (ECD) with multiple N-glycosylation sites.	Nitrogen	83-84	calcitonin receptor	Homo sapiens	25-28
33168411-6	2021	Our data reveal that BTK is activated in DCs, neutrophils, and B cells which causes an increase in AKI associated biochemical markers such as serum creatinine/blood urea nitrogen, renal myeloperoxidase activity, and histopathological disturbances in renal tubular structures.	Nitrogen	170-178	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	21-24
33168411-8	2021	Treatment with BTK inhibitor, Ibrutinib causes attenuation in AKI associated dysfunction in biochemical parameters (serum creatinine/blood urea nitrogen, renal myeloperoxidase activity) and oxidative stress in immune cells and kidney (iNOS/NOX2/lipid peroxides/nitrotyrosine/protein carbonyls).	Nitrogen	144-152	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	15-18
32971315-6	2021	The most important O&NS biomarkers predicting an increased SBP were in descending order of significance: LOOH, AOPP and SOD.	Nitrogen	21-23	superoxide dismutase 1	Homo sapiens	120-123
32901097-6	2021	This study demonstrates molecular insights into hyperosmolarity effect on OSCC development and shows that NFAT5 transcription factor plays an important functional role in enhancing the oral cancer cell proliferation by inducing the EGFR translocation from the endoplasmic reticulum to the plasma membrane through increase the expression of DPAGT1, an essential enzyme for catalyzing the first committed step of N-linked protein glycosylation.	Nitrogen	106-107	epidermal growth factor receptor	Homo sapiens	232-236
32814187-0	2021	Nitrogen-rich g-C3N4@AgPd Mott-Schottky heterojunction boosts photocatalytic hydrogen production from water and tandem reduction of NO3- and NO2.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	132-135
32818675-2	2021	In this paper, a novel structure of nitrogen-doped carbon nanotubes-encapsulated cobalt nanoparticles (Co@NCNTs) is synthesized by a simple dual-template strategy using silica colloid and tri-block copolymer (polyethylene oxide-polypropylene oxide-polyethylene oxide, PEO-PPO-PEO, F127) as hard and soft templates, respectively.	Nitrogen	36-44	protoporphyrinogen oxidase	Homo sapiens	272-275
33166864-6	2021	It was found that hydrophobic interactions, along with hydrogen-bonding via the imidazole nitrogen heteroatom, promoted interactions with the Abeta peptide, thereby limiting its aggregation.	Nitrogen	90-98	amyloid beta precursor protein	Homo sapiens	142-147
33370382-5	2020	Analyses of site-specific glycans revealed that SP swapping altered Env glycan content and occupancy on multiple N-linked glycosites, including conserved N156 and N160 glycans in the V1V2 region at the Env trimer apex and N88 at the trimer base.	Nitrogen	113-114	endogenous retrovirus group W member 1, envelope	Homo sapiens	68-71
33129879-8	2021	We found that STZ-induced ATF4 KO mice showed significant improvement in urinary albumin, serum creatinine and blood urea nitrogen and the pathological changes of renal tubulointerstitial fibrosis compared with STZ-induced WT mice.	Nitrogen	122-130	activating transcription factor 4	Mus musculus	26-30
33616978-6	2021	(b) A transient transfection assay with plasmids expressing EGFP-tagged GP119.1 or its mutated forms identified its true translational initiation site, localization mainly in the endoplasmic reticulum, and N-glycosylation.	Nitrogen	206-207	GP119.1	Caviid betaherpesvirus 2	72-79
33616978-8	2021	(d) GP119.1 is present in the virion with a molecular mass of 15 and 23~30 kDa, and a portion of the GP119.1 products are N-glycosylated.	Nitrogen	122-123	GP119.1	Caviid betaherpesvirus 2	101-108
33231608-0	2020	N-Glycosylation at Asn695 might suppress inducible nitric oxide synthase activity by disturbing electron transfer.	Nitrogen	0-1	nitric oxide synthase 2, inducible	Mus musculus	41-72
33231608-4	2020	Mass spectrometry studies identified Asn695 as an N-glycosylation site of murine iNOS.	Nitrogen	50-51	nitric oxide synthase 2, inducible	Mus musculus	81-85
33231608-9	2020	Taken together, our results indicate that iNOS is N-glycosylated at its Asn695 residue and N-glycosylation of Asn695 might suppress iNOS activity by disturbing electron transfer.	Nitrogen	43-44	nitric oxide synthase 2, inducible	Mus musculus	132-136
33231608-9	2020	Taken together, our results indicate that iNOS is N-glycosylated at its Asn695 residue and N-glycosylation of Asn695 might suppress iNOS activity by disturbing electron transfer.	Nitrogen	50-51	nitric oxide synthase 2, inducible	Mus musculus	42-46
33231608-9	2020	Taken together, our results indicate that iNOS is N-glycosylated at its Asn695 residue and N-glycosylation of Asn695 might suppress iNOS activity by disturbing electron transfer.	Nitrogen	50-51	nitric oxide synthase 2, inducible	Mus musculus	132-136
33447350-7	2020	In addition, downmodulation of N-glycosylation by treatment with the inhibitors Tunicamycin/Swainsonine or MGAT5 silencing decreased SLex expression, adhesion and migration in high-grade glioma cells.	Nitrogen	31-32	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	107-112
32846348-0	2020	Biostimulation of a marine anammox bacteria-dominated bioprocess by Co(II) to treat nitrogen-rich, saline wastewater.	Nitrogen	84-92	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	68-74
33375721-6	2020	We found that, under nitrogen limitation, mcl-PHA accumulation is significantly lower in the mutant deficient in the stringent response than in the wild type or the rpoN mutant.	Nitrogen	21-29	RNA polymerase factor sigma-54	Pseudomonas putida KT2440	165-169
33458503-8	2021	Such a new three-dimensional spiral framework of sp2-hyperdized carbon and nitrogen atoms not only enriches the family of carbon nitride materials but also finds application in energy conversion and storage.	Nitrogen	75-83	Sp2 transcription factor	Homo sapiens	49-52
32846348-6	2020	The nitrogen removal with Co(II) addition could be well described by a modified Logistic model.	Nitrogen	4-12	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	26-32
33403271-0	2020	Multifunctional Binding Sites on Nitrogen-Doped Carboxylated Porous Carbon for Highly Efficient Adsorption of Pb(II), Hg(II), and Cr(VI) Ions.	Nitrogen	33-41	submaxillary gland androgen regulated protein 3B	Homo sapiens	110-116
33119209-3	2020	The heterojunction of p-CuInS2 and n-type polymer (both PNDI3OT-Se1 and Se2) successfully made p-n junctions and showed improved charge transfer.	Nitrogen	12-13	fucosyltransferase 2	Homo sapiens	72-75
32834760-5	2020	In addition, the organic nitrogen was converted mainly into NO3 - and NH4 + and small amounts of volatile nitrogen species (NH3 and NOx).	Nitrogen	25-33	NBL1, DAN family BMP antagonist	Homo sapiens	60-63
33339338-3	2020	Based on evidence from published crystal structures of harmine bound to each of these enzymes, we performed systematic structure modifications of harmine yielding DYRK1A-selective inhibitors characterized by small polar substituents at N-9 (which preserve DYRK1A inhibition and eliminate MAO-A inhibition) and beneficial residues at C-1 (methyl or chlorine).	Nitrogen	236-237	dual specificity tyrosine phosphorylation regulated kinase 1A	Homo sapiens	163-169
33403271-2	2020	This work reports the development of a novel chelating nitrogen-doped carboxylated porous carbon (ND-CPC) adsorbent for the effective removal of the heavy metal ions Pb(II), Hg(II), and Cr(VI) from contaminated and polluted water sources.	Nitrogen	55-63	submaxillary gland androgen regulated protein 3B	Homo sapiens	166-172
33326776-2	2020	Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine.	Nitrogen	60-61	deoxyhypusine synthase	Homo sapiens	0-22
33326776-2	2020	Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine.	Nitrogen	60-61	deoxyhypusine synthase	Homo sapiens	24-28
33276745-8	2020	RESULTS: Compared with sham group, the aortic root of ApoE-/- mice in the UAAS group developed early atherosclerosis, the levels of total cholesterol, triglyceride, low-density lipoprotein-cholesterol, serum creatinine and urea nitrogen were also higher than that in the sham group.	Nitrogen	228-236	apolipoprotein E	Mus musculus	54-58
32524825-6	2020	Reduction of SELENOT expression in transgenic cell and animal models leads to an accumulation of reactive oxygen and nitrogen species, depletion of Ca2+ stores, and activation of the unfolded protein response (UPR).	Nitrogen	117-125	selenoprotein T	Homo sapiens	13-20
33229537-5	2020	2) Glucocorticoid receptor (GR), an immunity-modulating transcription factor (TF), is up-regulated in 2-KO cells and also physically binds to UBR1, strongly suggesting that GR is a physiological substrate of the Arg/N-degron pathway.	Nitrogen	216-217	nuclear receptor subfamily 3 group C member 1	Homo sapiens	3-26
33229537-5	2020	2) Glucocorticoid receptor (GR), an immunity-modulating transcription factor (TF), is up-regulated in 2-KO cells and also physically binds to UBR1, strongly suggesting that GR is a physiological substrate of the Arg/N-degron pathway.	Nitrogen	216-217	nuclear receptor subfamily 3 group C member 1	Homo sapiens	28-30
33229537-5	2020	2) Glucocorticoid receptor (GR), an immunity-modulating transcription factor (TF), is up-regulated in 2-KO cells and also physically binds to UBR1, strongly suggesting that GR is a physiological substrate of the Arg/N-degron pathway.	Nitrogen	216-217	nuclear receptor subfamily 3 group C member 1	Homo sapiens	173-175
33183568-5	2020	APR was evaluated at M0, M3, M12 by measuring 3 days dietary intakes together with losses of nitrogen in urine and stools.	Nitrogen	93-101	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	0-3
33344081-5	2020	In addition, under salt stress, moderately low N application could maintain the expression of NR (nitrate reductase) and GS (glutamine synthetase) encoding genes at a relatively stable level but had no effect on the expression of detected NRT (nitrate transporter) gene.	Nitrogen	47-48	glutamate-ammonia ligase	Homo sapiens	125-145
33344081-6	2020	The seedlings cultured at 2.0 mM N also exhibited the highest activity of CAT and POD antioxidant enzymes and the lowest MDA content and EL under relative low level of salt treatment.	Nitrogen	33-34	catalase	Homo sapiens	74-77
33201982-3	2020	Here, we examined the roles of the C2 domain in endocytosis for the downregulation of the general amino acid permease Gap1, which is one of nitrogen-regulated permeases in S. cerevisiae.	Nitrogen	140-148	amino acid permease GAP1	Saccharomyces cerevisiae S288C	118-122
33201982-5	2020	These mutants showed defects in endocytosis of Gap1 in response to a preferred nitrogen source.	Nitrogen	79-87	amino acid permease GAP1	Saccharomyces cerevisiae S288C	47-51
32008086-9	2020	Finally, we found that CRBN can mediate the effect of thalidomide on EGFL6 expression and that the CRBN protein interacts with EGFL6 via a Lon N-terminal peptide.	Nitrogen	26-27	EGF like domain multiple 6	Homo sapiens	69-74
33232205-5	2020	The membrane (M) protein was partially N-linked glycosylated; the accessory protein 3a existed in three different forms, indicative of cleavage and dimerization.	Nitrogen	39-40	membrane glycoprotein	Severe acute respiratory syndrome coronavirus 2	14-15
33225042-7	2020	Moreover, our release study revealed that direct binding to NS in GF scaffolds provided stronger protection to BMP2 and sustained release compared to GF/NS composite scaffolds.	Nitrogen	60-62	bone morphogenetic protein 2	Mus musculus	111-115
33183568-6	2020	MAIN OUTCOME MEASURE: APR was defined as the mean value of protein intake required to achieve balance nitrogen equilibrium.	Nitrogen	102-110	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	22-25
33090332-2	2020	Extracellular ATP acting through the P2X7 receptor induces the maturation and release of pro-inflammatory cytokines (i.e., IL-1beta) and the production of reactive nitrogen and oxygen species that lead to oxidative tissue damage.	Nitrogen	164-172	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	37-50
31939313-1	2020	A series of nitrogen heterocycles containing alpha-ethoxyphenylpropionic acid derivatives were designed as dual PPARalpha/gamma agonist ligands for the treatment of type 2 diabetes (T2D) and its complications.	Nitrogen	12-20	peroxisome proliferator activated receptor alpha	Mus musculus	112-121
33125131-13	2020	Therefore, N-glycosylation is an important factor controlling invasiveness of liver cancer cells, and a specific N-glycan (m/z=1892) associated with the invasion of liver cancer cells via uPA was identified in the present study.	Nitrogen	11-12	plasminogen activator, urokinase	Homo sapiens	188-191
33164761-0	2020	MDR-1 function protects oocyte mitochondria against the transgenerational effects of nitrogen mustard exposure.	Nitrogen	85-93	ATP binding cassette subfamily B member 1	Homo sapiens	0-5
33425103-10	2020	Compared with that in normal mice, the expression of Stim1 in the kidney tissues of LN mice was significantly increased, and Stim1 expression was positively correlated with fibronectin, urine protein, blood urea nitrogen and serum creatinine levels.	Nitrogen	212-220	stromal interaction molecule 1	Mus musculus	125-130
33257855-2	2020	We previously demonstrated perturbed nitrogen metabolism and addiction to an unconventional pathway of pyrimidine synthesis in KRAS/LKB1 co-mutant cancer cells.	Nitrogen	37-45	serine/threonine kinase 11	Mus musculus	132-136
32867594-1	2020	Nitrate transporter 2.5 (NRT2.5) was originally characterized as the transporter for nitrogen (N) limitation.	Nitrogen	85-93	nitrate transporter 2:1	Arabidopsis thaliana	25-29
32867594-1	2020	Nitrate transporter 2.5 (NRT2.5) was originally characterized as the transporter for nitrogen (N) limitation.	Nitrogen	0-1	nitrate transporter 2:1	Arabidopsis thaliana	25-29
33150721-0	2020	Hierarchical Multicavity Nitrogen-Doped Carbon Nanospheres as Efficient Polyselenide Reservoir for Fast and Long-Life Sodium-Selenium Batteries.	Nitrogen	25-33	Fas activated serine/threonine kinase	Homo sapiens	99-103
33257673-8	2020	Our results show that maternal dietary n-3 PUFA deficiency increases microglia-mediated phagocytosis of synaptic elements in the rodent developing hippocampus, partly through the activation of 12/15-lipoxygenase (LOX)/12-HETE signaling, altering neuronal morphology and affecting cognitive performance of the offspring.	Nitrogen	27-28	arachidonate 15-lipoxygenase	Mus musculus	193-211
33169535-4	2020	The combined results of experimental data and density functional theory calculations indicate that Cu bound with N (particularly Cu-N2 ) is the key to favorable adsorption of NO3 - and NO2 - .	Nitrogen	113-114	NBL1, DAN family BMP antagonist	Homo sapiens	175-178
33257673-8	2020	Our results show that maternal dietary n-3 PUFA deficiency increases microglia-mediated phagocytosis of synaptic elements in the rodent developing hippocampus, partly through the activation of 12/15-lipoxygenase (LOX)/12-HETE signaling, altering neuronal morphology and affecting cognitive performance of the offspring.	Nitrogen	27-28	arachidonate 15-lipoxygenase	Mus musculus	213-216
33188670-0	2020	Unveiling the potential of superalkali cation Li3+ for capturing nitrogen.	Nitrogen	65-73	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	46-49
33261212-4	2020	AGEs, by binding to receptors for AGE (RAGEs), alter innate and adaptive immune responses to induce inflammation and immunosuppression via the generation of proinflammatory cytokines, reactive oxygen species (ROS), and reactive nitrogen intermediates (RNI).	Nitrogen	228-236	renin binding protein	Homo sapiens	0-3
32458940-6	2020	The absorption bands and emission quantum yields of fac-[ReCl(CO)3(phet)] are sensitive to proton concentration due to an acid-basic equilibrium in the N atoms of the thiosemicarbazone.	Nitrogen	152-153	FA complementation group C	Homo sapiens	52-55
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	Vam7p	Saccharomyces cerevisiae S288C	141-145
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	Rab family GTPase YPT7	Saccharomyces cerevisiae S288C	150-154
32921411-0	2020	N-glycosylation of Siglec-15 decreases its lysosome-dependent degradation and promotes its transportation to the cell membrane.	Nitrogen	0-1	sialic acid binding Ig like lectin 15	Homo sapiens	19-28
32921411-3	2020	Here, we identified the important post-translational modification, N-glycosylation of Siglec-15, which is regulated by glucose uptake.	Nitrogen	67-68	sialic acid binding Ig like lectin 15	Homo sapiens	86-95
32921411-4	2020	Using a series of glycosidase and glycosylation inhibitors, we demonstrated that Siglec-15 was completely N-glycosylated in vitro and in vivo.	Nitrogen	106-107	sialic acid binding Ig like lectin 15	Homo sapiens	81-90
32921411-6	2020	N-glycosylation stabilized Siglec-15 by decreasing its lysosome-dependent degradation.	Nitrogen	0-1	sialic acid binding Ig like lectin 15	Homo sapiens	27-36
32921411-7	2020	Siglec-15 subcellular distribution detected by immunofluorescence indicated that N-glycosylation promoted Siglec-15 transportation to the cell membrane.	Nitrogen	81-82	sialic acid binding Ig like lectin 15	Homo sapiens	0-9
32921411-7	2020	Siglec-15 subcellular distribution detected by immunofluorescence indicated that N-glycosylation promoted Siglec-15 transportation to the cell membrane.	Nitrogen	81-82	sialic acid binding Ig like lectin 15	Homo sapiens	106-115
32921411-8	2020	The collective observations indicate that targeting the N-glycosylation of Siglec-15 may be an effective supplement to immunotherapy.	Nitrogen	56-57	sialic acid binding Ig like lectin 15	Homo sapiens	75-84
33188670-6	2020	In addition, it can be concluded that the superalkali cation Li3+ surpasses heavy alkali metal cations in capturing N2 molecules, since it has a larger binding energy with N2 than Na+ and K+ ions.	Nitrogen	116-118	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	61-64
33188670-6	2020	In addition, it can be concluded that the superalkali cation Li3+ surpasses heavy alkali metal cations in capturing N2 molecules, since it has a larger binding energy with N2 than Na+ and K+ ions.	Nitrogen	172-174	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	61-64
33188670-1	2020	The potential of the superalkali cation Li3+ for capturing N2 and its behavior in gaseous nitrogen have been theoretically studied at the MP2/6-311+G(d) level.	Nitrogen	59-61	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	40-43
33188670-1	2020	The potential of the superalkali cation Li3+ for capturing N2 and its behavior in gaseous nitrogen have been theoretically studied at the MP2/6-311+G(d) level.	Nitrogen	90-98	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	40-43
33188670-2	2020	The evolution of structures and stability of the Li3+(N2)n (n = 1-7) complexes shows that the N2 molecules tend to bind to different vertices of the Li3+ core, and that Li3+ might have the capacity to capture up to twelve nitrogen molecules in the first coordination shell.	Nitrogen	54-56	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	49-52
33188670-2	2020	The evolution of structures and stability of the Li3+(N2)n (n = 1-7) complexes shows that the N2 molecules tend to bind to different vertices of the Li3+ core, and that Li3+ might have the capacity to capture up to twelve nitrogen molecules in the first coordination shell.	Nitrogen	54-56	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	149-152
32785584-1	2020	Nitrification is the microbial conversion of reduced forms of nitrogen (N) to nitrate (NO3-), and in fertilized soils it can lead to substantial N losses via NO3- leaching or nitrous oxide (N2O) production.	Nitrogen	0-1	NBL1, DAN family BMP antagonist	Homo sapiens	87-90
33188670-2	2020	The evolution of structures and stability of the Li3+(N2)n (n = 1-7) complexes shows that the N2 molecules tend to bind to different vertices of the Li3+ core, and that Li3+ might have the capacity to capture up to twelve nitrogen molecules in the first coordination shell.	Nitrogen	54-56	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	149-152
33188670-2	2020	The evolution of structures and stability of the Li3+(N2)n (n = 1-7) complexes shows that the N2 molecules tend to bind to different vertices of the Li3+ core, and that Li3+ might have the capacity to capture up to twelve nitrogen molecules in the first coordination shell.	Nitrogen	222-230	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	49-52
33202661-2	2020	The nutrient-depending signaling depends on the kinases mTOR (mechanistic target of rapamycin), which is mainly activated by nitrogen-resources, and PKA (protein kinase A), which is mainly activated by glucose, as well as both of their associated factors.	Nitrogen	125-133	mechanistic target of rapamycin kinase	Homo sapiens	56-60
32907713-0	2020	Nitrate reductase is a key enzyme responsible for nitrogen-regulated auxin accumulation in Arabidopsis roots.	Nitrogen	50-58	nitrate reductase 1	Arabidopsis thaliana	0-17
32907713-1	2020	Nitrate reductase (NR) is one of the key enzymes for plant nitrogen assimilation and root architecture remodeling.	Nitrogen	59-67	nitrate reductase 1	Arabidopsis thaliana	0-17
32907713-1	2020	Nitrate reductase (NR) is one of the key enzymes for plant nitrogen assimilation and root architecture remodeling.	Nitrogen	59-67	nitrate reductase 1	Arabidopsis thaliana	19-21
32907713-2	2020	However, crosstalk between NR-mediated signaling and auxin-mediated root development in nitrogen-status responses has not been investigated in details before.	Nitrogen	88-96	nitrate reductase 1	Arabidopsis thaliana	27-29
33147944-0	2020	All-in-One MoS2 Nanosheets Tailored by Porous Nitrogen-Doped Graphene for Fast and Highly Reversible Sodium Storage.	Nitrogen	46-54	Fas activated serine/threonine kinase	Homo sapiens	74-78
33202661-2	2020	The nutrient-depending signaling depends on the kinases mTOR (mechanistic target of rapamycin), which is mainly activated by nitrogen-resources, and PKA (protein kinase A), which is mainly activated by glucose, as well as both of their associated factors.	Nitrogen	125-133	mechanistic target of rapamycin kinase	Homo sapiens	62-93
33202661-9	2020	In contrast, the inhibition of mTOR by shifting cells from oleate-medium, which lacks glucose, to pexophagy-medium, which contains glucose and is limited in nitrogen, required Ras2-activity for efficient pexophagy, strongly suggesting that the role of Ras2 in glucose sensing-associated signaling is more important in this context than its co-function in mTOR-related autophagy-inhibition.	Nitrogen	157-165	mechanistic target of rapamycin kinase	Homo sapiens	31-35
33292704-12	2020	Incorporating the effect of specific signaling AA and the differential role of energy sources on utilization of absorbed AA for milk protein synthesis seems like the evident following step in nutrient requirement systems to further improve N efficiency in lactating dairy cow rations.	Nitrogen	240-241	casein beta	Bos taurus	128-140
33240631-5	2020	Grain yield decreased by -3%, 7.7%, and 21.9% when the N application rates decreased by 25%, 50%, and 100% from 300 Kg ha-1.	Nitrogen	55-56	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	119-123
33240631-9	2020	Our results suggest that application of N at 225 Kg ha-1 can increased yield by improving the RUE, WUE, and NUE in semi-arid regions.	Nitrogen	40-41	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	52-56
32721729-12	2020	In addition, the removal rate of total N-DBP precursors may be higher than that of TFP, leading to overly optimistic evaluation of precursor removal in water treatment practice.	Nitrogen	39-40	D-box binding PAR bZIP transcription factor	Homo sapiens	41-44
33045166-1	2020	We report herein an efficient chemical synthesis of homogeneous human E-cadherin N-linked glycopeptides consisting of a heptapeptide sequence adjacent to the Asn-633 N-glycosylation site with representative N-glycan structures, including a conserved trisaccharide, a core-fucosylated tetrasaccharide, and a complex-type biantennary octasaccharide.	Nitrogen	81-82	cadherin 1	Homo sapiens	70-80
33343341-5	2020	While pre-administration of gastrin ameliorated I/R-induced renal pathological damage, as reflected by the levels of serum creatinine and blood urea nitrogen, hematoxylin and eosin staining and periodic acid-Schiff staining.	Nitrogen	149-157	gastrin	Mus musculus	28-35
33048560-4	2020	Finally, the density functional theory calculation shows that the inert C-N bond activation reaction is not a concerted process; on the contrary, the coupling reaction first generates indole quaternary ammonium salt, and then C-N bond cleavage occurs via an SN2 process.	Nitrogen	74-75	solute carrier family 38 member 5	Homo sapiens	258-261
33048522-1	2020	The mitochondrial outer membrane protein, mitoNEET (mNT), is an iron-sulfur protein containing an Fe2S2(His)1(Cys)3 cluster with a unique single Fe-N bond.	Nitrogen	46-47	translocase of outer mitochondrial membrane 40	Homo sapiens	4-40
33182302-0	2020	The Arabidopsis L-Type Amino Acid Transporter 5 (LAT5/PUT5) Is Expressed in the Phloem and Alters Seed Nitrogen Content When Knocked Out.	Nitrogen	103-111	Amino acid permease family protein	Arabidopsis thaliana	54-58
33076661-3	2020	[CuII(H2O)8/3]3/2[FeII(CN)5(NH3)] showed higher catalytic activity than [CoII(H2O)8/3]3/2[FeII(CN)5(NH3)] and [GaIII(H2O)][FeII(CN)5(NH3)], although N-bound CuII species has been reported as less active than CoII and GaIII species in conventional PBAs.	Nitrogen	24-25	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	73-77
33153238-6	2020	The experimental results show that the RP2 of the three attributes of Total Carbon, Total Nitrogen, and Alkaline Nitrogen on the small dataset are 0.94, 0.95, 0.87, respectively, and the RP2 of the attributes of Organic Carbon, Nitrogen, and Clay on the LUCAS dataset are, respectively, 0.95, 0.91, 0.83, And compared with traditional regression models and new prediction methods commonly used in soil nutrient prediction, the multi-task model proposed in this paper is more accurate.	Nitrogen	90-98	RP2 activator of ARL3 GTPase	Homo sapiens	39-42
33153238-6	2020	The experimental results show that the RP2 of the three attributes of Total Carbon, Total Nitrogen, and Alkaline Nitrogen on the small dataset are 0.94, 0.95, 0.87, respectively, and the RP2 of the attributes of Organic Carbon, Nitrogen, and Clay on the LUCAS dataset are, respectively, 0.95, 0.91, 0.83, And compared with traditional regression models and new prediction methods commonly used in soil nutrient prediction, the multi-task model proposed in this paper is more accurate.	Nitrogen	113-121	RP2 activator of ARL3 GTPase	Homo sapiens	39-42
33153238-6	2020	The experimental results show that the RP2 of the three attributes of Total Carbon, Total Nitrogen, and Alkaline Nitrogen on the small dataset are 0.94, 0.95, 0.87, respectively, and the RP2 of the attributes of Organic Carbon, Nitrogen, and Clay on the LUCAS dataset are, respectively, 0.95, 0.91, 0.83, And compared with traditional regression models and new prediction methods commonly used in soil nutrient prediction, the multi-task model proposed in this paper is more accurate.	Nitrogen	113-121	RP2 activator of ARL3 GTPase	Homo sapiens	39-42
33076661-3	2020	[CuII(H2O)8/3]3/2[FeII(CN)5(NH3)] showed higher catalytic activity than [CoII(H2O)8/3]3/2[FeII(CN)5(NH3)] and [GaIII(H2O)][FeII(CN)5(NH3)], although N-bound CuII species has been reported as less active than CoII and GaIII species in conventional PBAs.	Nitrogen	24-25	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	208-212
32408394-0	2020	Acute cytotoxicity and increased vascular endothelial growth factor after in vitro nitrogen mustard vapor exposure.	Nitrogen	83-91	vascular endothelial growth factor A	Homo sapiens	33-67
31939057-7	2020	Severe diminution of the antioxidant enzymes like superoxide dismutase, catalase, and GPx increases the tissue damage by reactive oxygen and nitrogen species.	Nitrogen	141-149	catalase	Homo sapiens	72-80
33179535-11	2020	TNF-alpha also induced an inflammatory response in SaOs-2 cells, as evidenced by the release of reactive oxygen and nitrogen species and the proinflammatory cytokine vascular endothelial growth factor.	Nitrogen	116-124	tumor necrosis factor	Homo sapiens	0-9
33142417-8	2020	Moreover, the preliminary structure-activity relationship and docking studies revealed that replacement of a nitrogen-containing heterocycle on the R2 (block A) group might improve the c-Met kinase inhibitory and antiproliferative effects in MDA-MB-231 cells, whereas displacement by a substituted benzene ring, especially for the p-fluorophenyl or 4-fluoro-3-methoxyphenyl moiety, on the R2 group enhanced cytotoxicity toward A549 cells.	Nitrogen	109-117	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	185-190
32898512-13	2020	Redox imbalance takes place due to an enhancement in ROS and reactive nitrogen species production from different sources, such as NOX family and iNOS, respectively, in an onset where the antioxidant defenses are overwhelmed due to an impaired Nrf2 signaling, leading to oxidative damage to macromolecules.	Nitrogen	70-78	nitric oxide synthase 2	Rattus norvegicus	145-149
32645597-7	2020	In the system containing 10 mg L-1 As(III) and 1.0 g L-1 Fe-Mn nodules, the maximum oxidation capacity of As(III) reached 3.22, 3.48 and 3.71 mg g-1, and the corresponding As(III,V) adsorption capacity reached 2.49, 2.40, and 2.39 mg g-1 in nitrogen, air and oxygen atmosphere, respectively.	Nitrogen	241-249	L1 cell adhesion molecule	Homo sapiens	31-34
32645597-7	2020	In the system containing 10 mg L-1 As(III) and 1.0 g L-1 Fe-Mn nodules, the maximum oxidation capacity of As(III) reached 3.22, 3.48 and 3.71 mg g-1, and the corresponding As(III,V) adsorption capacity reached 2.49, 2.40, and 2.39 mg g-1 in nitrogen, air and oxygen atmosphere, respectively.	Nitrogen	241-249	L1 cell adhesion molecule	Homo sapiens	53-56
32893186-1	2020	Aldehyde oxidase (AO) efficiently metabolizes a range of compounds with N-containing heterocyclic aromatic rings and/or aldehydes.	Nitrogen	72-73	aldehyde oxidase 1	Homo sapiens	0-16
32931036-0	2020	N-linked glycosylation of the mGlu7 receptor regulates the forward trafficking and transsynaptic interaction with Elfn1.	Nitrogen	0-1	extracellular leucine rich repeat and fibronectin type III domain containing 1	Homo sapiens	114-119
32931036-9	2020	We find that N-glycosylation of mGlu7 promotes its interaction with Elfn1, thereby enabling proper localization and stable surface expression of mGlu7 at the presynaptic active zone.	Nitrogen	13-14	extracellular leucine rich repeat and fibronectin type III domain containing 1	Homo sapiens	68-73
32996649-9	2020	RESULTS: N-glycosylation enhanced the ability of CREBH to activate transcription and modulated the production of peroxisome proliferator-activated receptor alpha (PPARalpha) and stearoyl-CoA desaturase-1 (SCD-1) activity by affecting their promoter-driven transcription activity and protein interactions, leading to reduce lipid deposition and attenuate lipotoxicity.	Nitrogen	9-10	peroxisome proliferator activated receptor alpha	Mus musculus	113-161
32952646-9	2020	The concentrations of CD68 and TGF-beta1 in the study group positively correlated with the renal injury indexes, such as blood urea nitrogen (BUN), serum creatinine (SCR), uric acid (UA) and the 24-h urinary protein quantity (P<0.05).	Nitrogen	132-140	transforming growth factor beta 1	Homo sapiens	31-40
32996649-9	2020	RESULTS: N-glycosylation enhanced the ability of CREBH to activate transcription and modulated the production of peroxisome proliferator-activated receptor alpha (PPARalpha) and stearoyl-CoA desaturase-1 (SCD-1) activity by affecting their promoter-driven transcription activity and protein interactions, leading to reduce lipid deposition and attenuate lipotoxicity.	Nitrogen	9-10	peroxisome proliferator activated receptor alpha	Mus musculus	163-172
32996649-0	2020	N-glycosylation of CREBH improves lipid metabolism and attenuates lipotoxicity in NAFLD by modulating PPARalpha and SCD-1.	Nitrogen	0-1	peroxisome proliferator activated receptor alpha	Mus musculus	102-111
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	2-3	peroxisome proliferator activated receptor alpha	Mus musculus	258-267
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	9-10	peroxisome proliferator activated receptor alpha	Mus musculus	258-267
33143310-6	2020	Accompanying neuroprotection, IL-4 neutralization inhibited activation of microglia/macrophages, reactive oxygen species-derived oxidative damages, production of myeloperoxidase- and inducible nitric oxide synthase-derived reactive nitrogen species and nitrosative damages as analyzed by immunohistochemistry and hydroethidine histochemistry.	Nitrogen	232-240	nitric oxide synthase 2	Rattus norvegicus	183-214
32745880-0	2020	n-3 PUFAs inhibit TGFbeta1-induced profibrogenic gene expression by ameliorating the repression of PPARgamma in hepatic stellate cells.	Nitrogen	0-1	transforming growth factor beta 1	Homo sapiens	18-26
32745880-0	2020	n-3 PUFAs inhibit TGFbeta1-induced profibrogenic gene expression by ameliorating the repression of PPARgamma in hepatic stellate cells.	Nitrogen	0-1	peroxisome proliferator activated receptor gamma	Homo sapiens	99-108
32666865-2	2020	N-linked glycosylation, by modifying protein functions, may provide an important environmental link predicting vulnerability.Our goals were (1) to find alterations in plasma N-glycome predicting stress-vulnerability; (2) to investigate how trauma affects N-glycome in the plasma (PGP) and in three PTSD-related brain regions (prefrontal cortex, hippocampus and amygdala; BGP), hence uncover specific targets for PTSD treatment.	Nitrogen	0-1	phosphoglycolate phosphatase	Rattus norvegicus	280-283
32815023-0	2020	Variation in the hemostatic complement (C5a) responses to in vitro nitrogen bubbles in monodontids and phocids.	Nitrogen	67-75	complement C5a receptor 1	Homo sapiens	40-43
32979455-4	2020	Recent studies have provided insights on the localization of enzymes that synthesise reactive oxygen or nitrogen species (ROS or RNS respectively) in plasma membrane compartments (raft/caveolae) which also harbour PUFA esters, from which free acid forms can be released by phospholipase A2 activity (PLA2), and the complex of Nrf2 with the inhibitory protein Kelch-like ECH-associated Protein 1(Keap1).	Nitrogen	104-112	phospholipase A2 group IB	Homo sapiens	273-289
32979455-4	2020	Recent studies have provided insights on the localization of enzymes that synthesise reactive oxygen or nitrogen species (ROS or RNS respectively) in plasma membrane compartments (raft/caveolae) which also harbour PUFA esters, from which free acid forms can be released by phospholipase A2 activity (PLA2), and the complex of Nrf2 with the inhibitory protein Kelch-like ECH-associated Protein 1(Keap1).	Nitrogen	104-112	phospholipase A2 group IB	Homo sapiens	300-304
32979455-4	2020	Recent studies have provided insights on the localization of enzymes that synthesise reactive oxygen or nitrogen species (ROS or RNS respectively) in plasma membrane compartments (raft/caveolae) which also harbour PUFA esters, from which free acid forms can be released by phospholipase A2 activity (PLA2), and the complex of Nrf2 with the inhibitory protein Kelch-like ECH-associated Protein 1(Keap1).	Nitrogen	104-112	NFE2 like bZIP transcription factor 2	Homo sapiens	326-330
32979455-4	2020	Recent studies have provided insights on the localization of enzymes that synthesise reactive oxygen or nitrogen species (ROS or RNS respectively) in plasma membrane compartments (raft/caveolae) which also harbour PUFA esters, from which free acid forms can be released by phospholipase A2 activity (PLA2), and the complex of Nrf2 with the inhibitory protein Kelch-like ECH-associated Protein 1(Keap1).	Nitrogen	104-112	kelch like ECH associated protein 1	Homo sapiens	359-394
32979455-4	2020	Recent studies have provided insights on the localization of enzymes that synthesise reactive oxygen or nitrogen species (ROS or RNS respectively) in plasma membrane compartments (raft/caveolae) which also harbour PUFA esters, from which free acid forms can be released by phospholipase A2 activity (PLA2), and the complex of Nrf2 with the inhibitory protein Kelch-like ECH-associated Protein 1(Keap1).	Nitrogen	104-112	kelch like ECH associated protein 1	Homo sapiens	395-400
32887004-5	2020	Results showed that the cumulative CO2 and N2O emission from 9000 kg ha-1 of maize straw mulch with 192 kg N ha-1 (S3N2) significantly decreased by 0.67% and 33.7%, respectively, averaged over two years compared with that of 9000 kg ha-1 of maize straw mulch with 240 kg N ha-1 (S3N3).	Nitrogen	43-44	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	69-73
32887004-5	2020	Results showed that the cumulative CO2 and N2O emission from 9000 kg ha-1 of maize straw mulch with 192 kg N ha-1 (S3N2) significantly decreased by 0.67% and 33.7%, respectively, averaged over two years compared with that of 9000 kg ha-1 of maize straw mulch with 240 kg N ha-1 (S3N3).	Nitrogen	43-44	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	109-113
32887004-5	2020	Results showed that the cumulative CO2 and N2O emission from 9000 kg ha-1 of maize straw mulch with 192 kg N ha-1 (S3N2) significantly decreased by 0.67% and 33.7%, respectively, averaged over two years compared with that of 9000 kg ha-1 of maize straw mulch with 240 kg N ha-1 (S3N3).	Nitrogen	107-108	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	69-73
32887004-5	2020	Results showed that the cumulative CO2 and N2O emission from 9000 kg ha-1 of maize straw mulch with 192 kg N ha-1 (S3N2) significantly decreased by 0.67% and 33.7%, respectively, averaged over two years compared with that of 9000 kg ha-1 of maize straw mulch with 240 kg N ha-1 (S3N3).	Nitrogen	107-108	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	109-113
32817316-6	2020	No N-glycosylation signals were detected in SLP-8348 and SLP-8321, but SLP-5818 was observed to have two sites carrying complex N-glycans based on a site-specific analysis and a glycomic workflow of the permethylated glycans.	Nitrogen	0-1	superkiller viralicidic activity 2-like (S. cerevisiae), pseudogene 1	Mus musculus	44-47
33105776-6	2020	The results of low-temperature nitrogen sorption analysis indicated that an increase in the iron(II, III) oxide content leads to a decrease in the BET surface area.	Nitrogen	31-39	putative DNA recombination protein Bet	Escherichia coli	147-150
33066819-9	2020	Nitrate reductase, nitrite reductase, glutamine synthetase, glutamine oxoglutarate aminotransferase and asparagine synthetase enzyme have a great role in nitrogen metabolism.	Nitrogen	154-162	glutamate-ammonia ligase	Homo sapiens	38-58
32931535-2	2020	The reaction, which is catalyzed by a Bi(OAc)3/CPA system, gives a range of chiral nitrogen-containing heterocycle structures in high yields and with good enantioselectivities.	Nitrogen	83-91	carboxypeptidase A1	Homo sapiens	47-50
32817316-6	2020	No N-glycosylation signals were detected in SLP-8348 and SLP-8321, but SLP-5818 was observed to have two sites carrying complex N-glycans based on a site-specific analysis and a glycomic workflow of the permethylated glycans.	Nitrogen	0-1	superkiller viralicidic activity 2-like (S. cerevisiae), pseudogene 1	Mus musculus	57-60
32817316-6	2020	No N-glycosylation signals were detected in SLP-8348 and SLP-8321, but SLP-5818 was observed to have two sites carrying complex N-glycans based on a site-specific analysis and a glycomic workflow of the permethylated glycans.	Nitrogen	0-1	superkiller viralicidic activity 2-like (S. cerevisiae), pseudogene 1	Mus musculus	57-60
32784033-7	2020	Furthermore, the DBPs from chlorination of the soil-derived DOM showed lowered microtoxicity with N addition possibly due to reduced brominated DBP formation.	Nitrogen	98-99	D-box binding PAR bZIP transcription factor	Homo sapiens	17-20
33048135-12	2021	CYP3A4 was involved in the formation of all phase I metabolites of both NPS, while UGT1A4 and UGT2B10 catalyzed their N-glucuronidation.	Nitrogen	72-73	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-6
32975449-0	2020	Retraction of: Reactive Nitrogen Species Induced by Hyperglycemia Suppresses Akt Signaling and Triggers Apoptosis by Upregulating Phosphatase PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) in an LKB1-Dependent Manner.	Nitrogen	24-32	AKT serine/threonine kinase 1	Homo sapiens	77-80
33240780-4	2020	The hydrophobic CFP surface facilitates efficient three-phase contact points (TPCPs) for N2 (gas), electrolyte (liquid), and Au NPs (solid).	Nitrogen	89-91	complement factor properdin	Homo sapiens	16-19
33059940-1	2021	BACKGROUND: Elevated blood urea nitrogen to serum albumin (BUN/ALB) ratio had been identified as an independent risk factor related to mortality in community-acquired and hospital-acquired pneumonia.	Nitrogen	32-40	albumin	Homo sapiens	50-57
33059940-1	2021	BACKGROUND: Elevated blood urea nitrogen to serum albumin (BUN/ALB) ratio had been identified as an independent risk factor related to mortality in community-acquired and hospital-acquired pneumonia.	Nitrogen	32-40	albumin	Homo sapiens	63-66
33124386-5	2020	The peak concentrations of ammonia nitrogen (NH4+-N) from April 1st to June 30th were 11.51 mg  L-1 and 4.44 mg  L-1in 2012 and 2013, respectively.	Nitrogen	35-43	L1 cell adhesion molecule	Homo sapiens	96-105
33036562-1	2020	BACKGROUND: High-affinity nitrate transporter 2 (NRT2) genes have been implicated in nitrate absorption and remobilization under nitrogen (N) starvation stress in many plant species, yet little is known about this gene family respond to various stresses often occurs in the production of rapeseed (Brassica napus L.).	Nitrogen	129-137	nitrate transporter 2:1	Arabidopsis thaliana	49-53
33036562-1	2020	BACKGROUND: High-affinity nitrate transporter 2 (NRT2) genes have been implicated in nitrate absorption and remobilization under nitrogen (N) starvation stress in many plant species, yet little is known about this gene family respond to various stresses often occurs in the production of rapeseed (Brassica napus L.).	Nitrogen	8-9	nitrate transporter 2:1	Arabidopsis thaliana	49-53
32914976-5	2020	Using CO2 uptake measurements, 31P NMR, ATR-FTIR deuterium exchange equilibrium and rates, 2D NOESY and density functional theory calculations, we show that the key is the proximity of the negatively charged nitrogen atoms on the anion to the alpha protons, which is governed not just by anion basicity, but by sterics.	Nitrogen	208-216	ATR serine/threonine kinase	Homo sapiens	40-43
32719549-0	2020	Suppression of G6PD induces the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin to block epithelial-mesenchymal transition and lymphatic metastasis.	Nitrogen	60-61	cadherin 1	Homo sapiens	92-102
32960574-1	2020	The affinity of AtO+ for around 20 model ligands (L), carrying functionalized oxygen, sulfur, and nitrogen atoms, has been assessed through a combined experimental and theoretical methodology.	Nitrogen	98-106	splicing factor-like protein	Arabidopsis thaliana	16-19
32719549-9	2020	CONCLUSIONS: Suppression of G6PD promoted the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin via activating the JNK pathway, which thus acted on OSCC metastasis.	Nitrogen	2-3	cadherin 1	Homo sapiens	106-116
33053104-5	2020	Topdressing nitrogen (150, 250, 350, and 450 kg ha-1) increased the traditional average daily accumulation rate by 586% relative to the control.	Nitrogen	12-20	Rho GTPase activating protein 45	Homo sapiens	48-52
33023108-2	2020	15N tracing experiments unraveled the assimilatory mechanism of nitrogen from nitrate into amino acids in the light and in darkness by the reactions of nitrate and nitrite reductases, glutamine synthetase, glutamate synthase, aspartate aminotransferase, and asparagine synthetase.	Nitrogen	64-72	glutamate-ammonia ligase	Homo sapiens	184-204
32388438-2	2020	In this paper, a novel electrochemical immunosensor with high selectivity and sensitivity for the detection of the depression marker human apolipoprotein A4 (Apo-A4) was successfully constructed using zeolite imidazole ester metal organic skeleton-nitrogen doped graphene composites (ZIF-8@N-Gr).	Nitrogen	248-256	apolipoprotein A4	Homo sapiens	139-156
32388438-2	2020	In this paper, a novel electrochemical immunosensor with high selectivity and sensitivity for the detection of the depression marker human apolipoprotein A4 (Apo-A4) was successfully constructed using zeolite imidazole ester metal organic skeleton-nitrogen doped graphene composites (ZIF-8@N-Gr).	Nitrogen	248-256	apolipoprotein A4	Homo sapiens	158-164
32891857-0	2020	Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds - Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and alpha-glycosidase inhibition properties.	Nitrogen	13-21	acetylcholinesterase (Cartwright blood group)	Homo sapiens	134-154
32719549-9	2020	CONCLUSIONS: Suppression of G6PD promoted the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin via activating the JNK pathway, which thus acted on OSCC metastasis.	Nitrogen	2-3	mitogen-activated protein kinase 8	Homo sapiens	136-139
32002708-2	2020	The AR N-terminal domain (NTD) possesses most transcriptional activity and is proposed as a potential target for CRPC drug development.	Nitrogen	7-8	androgen receptor	Homo sapiens	4-6
32002708-0	2020	Regression of castration-resistant prostate cancer by a novel compound QW07 targeting androgen receptor N-terminal domain.	Nitrogen	104-105	androgen receptor	Homo sapiens	86-103
32531254-5	2020	This implicated glycosylation as a factor in antibody recognition and synthetic peptides spanning the two N-linked and one O-linked glycosylation regions showed that SHBG recognition by monoclonal antibody 7H9 could be disrupted by a peptide spanning the O-linked glycosylation site.	Nitrogen	106-107	sex hormone binding globulin	Homo sapiens	166-170
32594432-3	2020	Experimental results showed that the stratified pattern caused little accumulation of NO2- and NO3-, which leads to a superior nitrogen removal performance compared with the mixed pattern.	Nitrogen	127-135	NBL1, DAN family BMP antagonist	Homo sapiens	95-98
32989641-7	2020	We suggest that the ATPase motifs and the Thr16 phosphorylation site of Dhh1 are crucial to its regulatory roles in pseudohyphal growth under low nitrogen conditions.	Nitrogen	146-154	DExD/H-box ATP-dependent RNA helicase DHH1	Saccharomyces cerevisiae S288C	72-76
32827291-0	2020	N-glycosylation of the human beta1,4-galactosyltransferase 4 is crucial for its activity and Golgi localization.	Nitrogen	0-1	beta-1,4-galactosyltransferase 4	Homo sapiens	29-60
32384986-6	2020	The degradation extent of ammonia nitrogen was upto 81% when the ammonia nitrogen degradation reaction was photocatalyzed by the hollow SiO2@BiOI(100:10) nanocomposite at an initial concentration of ammonia nitrogen of 10 mg L-1 and 25  C for 4 h. The reaction kinetics of ammonia nitrogen degradation was well simulated by the first-order reaction model.	Nitrogen	34-42	L1 cell adhesion molecule	Homo sapiens	225-235
32384986-6	2020	The degradation extent of ammonia nitrogen was upto 81% when the ammonia nitrogen degradation reaction was photocatalyzed by the hollow SiO2@BiOI(100:10) nanocomposite at an initial concentration of ammonia nitrogen of 10 mg L-1 and 25  C for 4 h. The reaction kinetics of ammonia nitrogen degradation was well simulated by the first-order reaction model.	Nitrogen	73-81	L1 cell adhesion molecule	Homo sapiens	225-235
32384986-6	2020	The degradation extent of ammonia nitrogen was upto 81% when the ammonia nitrogen degradation reaction was photocatalyzed by the hollow SiO2@BiOI(100:10) nanocomposite at an initial concentration of ammonia nitrogen of 10 mg L-1 and 25  C for 4 h. The reaction kinetics of ammonia nitrogen degradation was well simulated by the first-order reaction model.	Nitrogen	73-81	L1 cell adhesion molecule	Homo sapiens	225-235
32384986-6	2020	The degradation extent of ammonia nitrogen was upto 81% when the ammonia nitrogen degradation reaction was photocatalyzed by the hollow SiO2@BiOI(100:10) nanocomposite at an initial concentration of ammonia nitrogen of 10 mg L-1 and 25  C for 4 h. The reaction kinetics of ammonia nitrogen degradation was well simulated by the first-order reaction model.	Nitrogen	73-81	L1 cell adhesion molecule	Homo sapiens	225-235
32017087-1	2020	T-complex 11 like 2 (TCP11L2) is a protein containing a serine-rich region in its N-terminal region.	Nitrogen	82-83	t-complex 11 like 2	Bos taurus	0-19
32017087-1	2020	T-complex 11 like 2 (TCP11L2) is a protein containing a serine-rich region in its N-terminal region.	Nitrogen	82-83	t-complex 11 like 2	Bos taurus	21-28
32787102-2	2020	Seven derivatives with (a) nitrogen- and/or halogen-containing residue(s) had extraordinary potencies against ABCG2 (IC50 < 150 nM).	Nitrogen	27-35	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	110-115
32521046-5	2020	Furthermore, we show that both PIFs and ARF18 directly repress Qua-Quine Starch (QQS), which controls the allocation of carbon and nitrogen.	Nitrogen	131-139	auxin response factor 18	Arabidopsis thaliana	40-45
32823246-6	2020	Additionally, the activity of fructokinase and hexokinase, which are involved in hexose phosphorylation, and transcript levels of MdFRK2 and MdHK3 were significantly upregulated under nitrogen deficiency, and the hexose phosphate products F6P and G6P accumulated greatly in the roots.	Nitrogen	184-192	Hexokinase-1-like	Malus domestica	47-57
33101324-4	2020	We found that in Zea mays, NADP-malic enzyme (NADP-ME), PEP carboxykinase (PCK), and Rubisco activities were positively correlated with P. A positive correlation was also observed between both phosphoenolpyruvate carboxylase (PEPC) and Rubisco activity with leaf [N] in Sorghum bicolor.	Nitrogen	27-28	NADP-dependent malic enzyme	Zea mays	46-53
32967340-1	2020	Paraoxonase 1 (PON1) is the high density lipoprotein-associated esterase which inhibits the development of atherosclerosis by metabolizing lipid peroxidation products as well as hydrolyzing proatherogenic metabolite of homocysteine (Hcy), Hcy thiolactone, which otherwise reacts with lysine groups of proteins, thus forming N-Hcy-protein in a process referred to as protein N-homocysteinylation.	Nitrogen	17-18	paraoxonase 1	Homo sapiens	0-13
32959807-2	2020	It has been hypothesized that synthesis of oxidized nitrogen in the form of nitrate (NO3-) and nitrite (NO2-), occurred in the prebiotic anoxic Hadean atmosphere.	Nitrogen	52-60	NBL1, DAN family BMP antagonist	Homo sapiens	85-88
32786443-0	2020	Absolute Quantification of N-Glycosylation of Alpha-Fetoprotein Using Parallel Reaction Monitoring with Stable Isotope-Labeled N-Glycopeptide as an Internal Standard.	Nitrogen	27-28	alpha fetoprotein	Homo sapiens	46-63
32786443-3	2020	For this reason, specifically, the level of the aberrant N-glycosylation of AFP has been proposed as a HCC biomarker to improve diagnostic performance using targeted mass spectrometry (MS).	Nitrogen	57-58	alpha fetoprotein	Homo sapiens	76-79
32786443-4	2020	In this study, we developed an endoglycosidase-assisted absolute quantification (AQUA) method by which to measure N-glycosylated AFP levels in serum using liquid chromatography-parallel reaction monitoring with immunoprecipitation.	Nitrogen	114-115	alpha fetoprotein	Homo sapiens	129-132
32786443-6	2020	The efficacy of this method was demonstrated by quantifying the N-glycosylation of AFP in human serum.	Nitrogen	64-65	alpha fetoprotein	Homo sapiens	83-86
32786443-8	2020	Our method also had a linear dynamic range from 2 to 6000 ng/mL for N-glycosylated AFP levels.	Nitrogen	68-69	alpha fetoprotein	Homo sapiens	83-86
32786443-9	2020	Finally, the N-glycosylation levels of AFP were measured in HCC patients and in healthy donors with the coefficient of variation in both cases (<10% CV).	Nitrogen	13-14	alpha fetoprotein	Homo sapiens	39-42
32786443-10	2020	To the best of our knowledge, this is the first report of the AQUA of N-glycosylated AFP in human sera using a stable isotope-labeled glycopeptide as an internal standard.	Nitrogen	70-71	alpha fetoprotein	Homo sapiens	85-88
32721326-4	2020	Nitrogen addition led to an average H+ production of 4.0, 8.7, 11.4, 29.7 and 52.6 keq ha-1 yr-1, respectively, for the control, optimized urea, conventional urea, optimized NH4Cl and conventional NH4Cl plots.	Nitrogen	0-8	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	87-96
32721354-7	2020	The minimum TNsupply levels needed to achieve the maximum RY and N output were 325 and 392 kg ha-1, respectively.	Nitrogen	13-14	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	94-98
32721354-9	2020	As the N input increased past 209 kg ha-1, the NUE declined, at which point the TNsupply reached 433 kg ha-1.	Nitrogen	7-8	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	37-41
32721354-9	2020	As the N input increased past 209 kg ha-1, the NUE declined, at which point the TNsupply reached 433 kg ha-1.	Nitrogen	7-8	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	104-108
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	206-207	interleukin 13	Homo sapiens	79-84
33345499-3	2020	We conducted a meta-analysis to examine the responses of soil pH, total phosphorus (TP), available phosphorus (AP), as well as activities of alkaline phosphatase (AlP) and acid phosphatase (AcP) in soils to nitrogen addition amount, nitrogen type, experimental duration, and sampling depth.	Nitrogen	233-241	alkaline phosphatase, placental	Homo sapiens	141-161
33345499-5	2020	The results showed that nitrogen addition significantly reduced soil pH, TP and AlP activity, while significantly increased AcP activity, but had no significant effect on AP.	Nitrogen	24-32	alkaline phosphatase, placental	Homo sapiens	80-83
32899627-2	2020	Almost all of the COX2 imaging agents using celecoxib as backbone were chemically modified in the position of N-atom in the sulfonamide group.	Nitrogen	110-111	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	18-22
32402213-0	2020	N-Glycosylation Regulates Chitinase 3-like-1 and IL-13 Ligand Binding to IL-13 Receptor alpha2.	Nitrogen	0-1	interleukin 13	Homo sapiens	49-54
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	135-136	interleukin 13	Homo sapiens	62-67
32492566-8	2020	Biochar stimulated activities of beta-glucosidase and leucine aminopeptidase (by 33-39%) compared to N due to the coupling of C, N and P cycles in BC/N treated soil.	Nitrogen	129-130	carboxypeptidase Q	Homo sapiens	62-76
32492566-8	2020	Biochar stimulated activities of beta-glucosidase and leucine aminopeptidase (by 33-39%) compared to N due to the coupling of C, N and P cycles in BC/N treated soil.	Nitrogen	129-130	carboxypeptidase Q	Homo sapiens	62-76
33345499-9	2020	Across all nitrogen addition amounts, when the experiment duration was 3 to 10 years, soil TP content and AlP activity were significantly reduced.	Nitrogen	11-19	alkaline phosphatase, placental	Homo sapiens	106-109
32568423-3	2020	Atomic replacements of the Fe II by other metal(II) ions (e.g., Zn II /Co II ) via synthesizing isostructural trinuclear-complex precursors (Fe 2 Zn/Fe 2 Co), namely the "heteroatom modulator approach", realizes the inhibition of iron atoms aggregating toward nanoclusters with formation of a stable iron-dimer cluster in an optimal metal-nitrogen moiety within the carbon layer, clearly identified by direct transmission electron microscope imaging with X-ray absorption fine structure analyses.	Nitrogen	339-347	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	71-76
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	135-136	interleukin 13	Homo sapiens	79-84
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	206-207	interleukin 13	Homo sapiens	62-67
32402213-7	2020	Studies with primary lung epithelial cells also demonstrated that Chi3l1 inhibited, whereas IL-13 stimulated, N-glycosylation as evidenced by the ability of Chi3l1 to inhibit and IL-13 to stimulate the subunits of the oligosaccharide complex A and B (STT3A and STT3B).	Nitrogen	110-111	interleukin 13	Homo sapiens	92-97
32882902-5	2020	Notably, the meat from the pigs fed with the low dietary n-6/n-3 PUFA ratio had higher n-3 PUFA contents (p < 0.01) and lower n-6/n-3 PUFA ratio (p < 0.01).	Nitrogen	57-58	Polyunsaturated fatty acid percentage	Sus scrofa	65-69
32882902-5	2020	Notably, the meat from the pigs fed with the low dietary n-6/n-3 PUFA ratio had higher n-3 PUFA contents (p < 0.01) and lower n-6/n-3 PUFA ratio (p < 0.01).	Nitrogen	57-58	Polyunsaturated fatty acid percentage	Sus scrofa	91-95
32882902-5	2020	Notably, the meat from the pigs fed with the low dietary n-6/n-3 PUFA ratio had higher n-3 PUFA contents (p < 0.01) and lower n-6/n-3 PUFA ratio (p < 0.01).	Nitrogen	57-58	Polyunsaturated fatty acid percentage	Sus scrofa	91-95
32402213-8	2020	These studies demonstrate that N-glycosylation is a critical determinant of Chi3l1 and IL-13 binding to IL-13Ralpha2, and highlight the ability of Chi3l1 and IL-13 to alter key elements of the N-glycosylation apparatus in a manner that would augment their respective binding.	Nitrogen	31-32	interleukin 13	Homo sapiens	87-92
32402213-8	2020	These studies demonstrate that N-glycosylation is a critical determinant of Chi3l1 and IL-13 binding to IL-13Ralpha2, and highlight the ability of Chi3l1 and IL-13 to alter key elements of the N-glycosylation apparatus in a manner that would augment their respective binding.	Nitrogen	31-32	interleukin 13	Homo sapiens	104-109
32717439-2	2020	Investigation of their molecular structure revealed that both complexes are isostructural and form analogous complex molecules, with a Co(II) atom hexacoordinated by two nitrogen atoms of bcp and four oxygen atoms of two chelate bonded flu (1) and nif (2) ligands in a distorted octahedral arrangement.	Nitrogen	170-178	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	135-141
32473471-3	2020	The optimal total nitrogen removal efficiency of 99.4% was achieved at NH4+/NO3- of 0.75 and S2O32-/NO3- of 0.85.	Nitrogen	18-26	NBL1, DAN family BMP antagonist	Homo sapiens	76-79
32473471-3	2020	The optimal total nitrogen removal efficiency of 99.4% was achieved at NH4+/NO3- of 0.75 and S2O32-/NO3- of 0.85.	Nitrogen	18-26	NBL1, DAN family BMP antagonist	Homo sapiens	100-103
32603908-1	2020	Acute phase response (APR) following intravenous zoledronate (ZOL) administration is related to activation and increased proliferation of gammadelta T cells, attributed to the molecular mechanism of action of nitrogen-containing bisphosphonates (N-BPs).	Nitrogen	209-217	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	22-25
32696400-2	2020	These two structures are characterized by a significant torsion of the methyl group and flattened geometry of the phenyl rings relative to the plane of the heteroaromatic ring, as well as sp3 hybridization of a nitrogen atom.	Nitrogen	211-219	Sp3 transcription factor	Homo sapiens	188-191
32405873-3	2020	Two nitrogen levels induced expression of some interesting regulating genes, such as USE1, STX1B_2_3, SEC23, SEC24, SEC61A, HSP A1_8, HSP20, and HSP90B/TRA1.	Nitrogen	4-12	heat shock protein family B (small) member 6	Homo sapiens	134-139
31972245-2	2020	We identified that the N-terminal region (amino acids 41-152) of GRA6 (GRA6Nt) stimulates IFN-gamma production by both a microglia cell line and primary microglia purified from the brains of uninfected adult mice.	Nitrogen	23-24	interferon gamma	Mus musculus	90-99
32699171-0	2020	A SnRK1-ZmRFWD3-Opaque2 Signaling Axis Regulates Diurnal Nitrogen Accumulation in Maize Seeds.	Nitrogen	57-65	SNF1-related protein kinase	Zea mays	2-7
32474175-7	2020	The high n-3 PUFA diet increased the mRNA expression of EL, FABPpm, and Mfsd2a at both gestation days, compared to other groups.	Nitrogen	9-10	glutamatic-oxaloacetic transaminase 2, mitochondrial	Mus musculus	60-66
32474175-7	2020	The high n-3 PUFA diet increased the mRNA expression of EL, FABPpm, and Mfsd2a at both gestation days, compared to other groups.	Nitrogen	9-10	major facilitator superfamily domain containing 2A	Mus musculus	72-78
32474175-9	2020	The high n-3 PUFA diet also increased the mRNA expressions of BDNF, TrKB and CREB, as well as the protein concentration of pCREB as gestation progressed, compared to the other groups.	Nitrogen	9-10	cAMP responsive element binding protein 1	Mus musculus	77-81
32272331-0	2020	Sonochemical nitrogen fixation for the generation of NO2- and NO3- ions under high-powered ultrasound in aqueous medium.	Nitrogen	13-21	NBL1, DAN family BMP antagonist	Homo sapiens	62-65
32863217-1	2020	The Nrf2 transcription factor is induced by reactive oxygen and nitrogen species and is necessary for the adaptive response to exercise in mice.	Nitrogen	64-72	nuclear factor, erythroid derived 2, like 2	Mus musculus	4-8
32272331-3	2020	When the generation of NO2- and NO3- ions under US exposure was investigated for N2, O2 and Ar-bubbled solutions, no trace of NO2- was observed while NO3- was slightly generated.	Nitrogen	81-83	NBL1, DAN family BMP antagonist	Homo sapiens	32-35
32905343-0	2020	Adsorption Property of CS2 and COF2 on Nitrogen-Doped Anatase TiO2(101) Surfaces: A DFT Study.	Nitrogen	39-47	chorionic somatomammotropin hormone 2	Homo sapiens	23-26
32868851-0	2020	Nitrogen availability and genotype affect major nutritional quality parameters of tef grain grown under irrigation.	Nitrogen	0-8	TEF transcription factor, PAR bZIP family member	Homo sapiens	82-85
32736713-2	2020	Such coassembly of DL-AuNPs with NCA (NCA@DL-AuNPs) had a large specific surface area (788 m2/g), rich mesopores, and a high N content (4.93 at%).	Nitrogen	24-25	CEA cell adhesion molecule 4	Homo sapiens	33-36
32736713-2	2020	Such coassembly of DL-AuNPs with NCA (NCA@DL-AuNPs) had a large specific surface area (788 m2/g), rich mesopores, and a high N content (4.93 at%).	Nitrogen	24-25	CEA cell adhesion molecule 4	Homo sapiens	38-50
32820145-3	2020	Searching for new substrates of PC7, a quantitative proteomics screen for selective enrichment of N-glycosylated polypeptides secreted from hepatic HuH7 cells identified two human type-II transmembrane proteins of unknown function(s): Cancer Susceptibility Candidate 4 (CASC4) and Golgi Phosphoprotein of 130 kDa (GPP130/GOLIM4).	Nitrogen	98-99	proprotein convertase subtilisin/kexin type 7	Homo sapiens	32-35
32905343-2	2020	In this paper, the adsorption property of two kinds of key SF6 carbon-containing decomposition components (CS2 and COF2) on nitrogen-doped anatase TiO2(101) (N-TiO2) surfaces was simulated and analyzed based on density functional theory.	Nitrogen	124-132	chorionic somatomammotropin hormone 2	Homo sapiens	107-110
32905343-2	2020	In this paper, the adsorption property of two kinds of key SF6 carbon-containing decomposition components (CS2 and COF2) on nitrogen-doped anatase TiO2(101) (N-TiO2) surfaces was simulated and analyzed based on density functional theory.	Nitrogen	158-159	chorionic somatomammotropin hormone 2	Homo sapiens	107-110
32799510-5	2020	The main reaction step is the same in both of the cases, that is, the one leading to the terminal-carbene intermediate [Fe(Por)(OCH3)(CHCO2Et)] with simultaneous dinitrogen loss; however, the reduced species performs much better than the oxidized one.	Nitrogen	162-172	cytochrome p450 oxidoreductase	Homo sapiens	123-126
32826075-6	2021	Renal function, represented by serum creatinine, urea nitrogen and cystatin-C, was significantly decreased in the low-eGFR group (P<0.001 for all) at the time of renal biopsy.	Nitrogen	54-62	epidermal growth factor receptor	Homo sapiens	118-122
32212405-2	2020	Exploiting the generation of halenium ion through oxidative process and the protonation of the nitrogen containing function in HF/SbF 5 , the chlorination and iodination of classically inert C sp2 -H bonds of aromatic amines occurs.	Nitrogen	95-103	regulator of calcineurin 2	Homo sapiens	191-196
32776892-3	2020	Analysis of serum transferrin (TRF) isoforms, as the classical procedure used to identify a CDG patient, enables to predict pathological steps in the N-linked glycosylation process.	Nitrogen	150-151	transferrin	Homo sapiens	18-29
32823842-2	2020	The compounds react with Co(NCS)2 under conditions of crystal growth at room temperature to give single crystals of [{Co(rac-2)2(NCS)2} CHCl3]n, [Co(3)2(NCS)2]n and [{Co(4)2(NCS)2} CHCl3]n which possess (4,4) networks, with the Co centers acting as 4-connecting nodes.	Nitrogen	10-11	Rac family small GTPase 2	Homo sapiens	121-126
32823605-4	2020	The following values were obtained by using deposition process with N2 of HIT = 19.7 +- 4.1 GPa, EIT = 221 +- 2.1 GPa, and coefficient of friction (COF) = 0.35 +- 0.09.	Nitrogen	68-70	glycophorin A (MNS blood group)	Homo sapiens	92-95
32849657-5	2020	Knockout of the N-glycosylation gene N-acetylglucosaminyltransferase V (MGAT5) in HEK293 cells induced altered metabolism and continuous high MICA surface expression.	Nitrogen	16-17	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	37-70
32849657-5	2020	Knockout of the N-glycosylation gene N-acetylglucosaminyltransferase V (MGAT5) in HEK293 cells induced altered metabolism and continuous high MICA surface expression.	Nitrogen	16-17	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	72-77
31863596-14	2020	AD-O51.4-driven cell death, which exceeds TRAIL activity, is achieved due to the N-terminally fused polypeptide, containing VEGFA-derived effector peptides.	Nitrogen	81-82	vascular endothelial growth factor A	Homo sapiens	124-129
32875266-2	2020	The sp-hybridized O and N atoms form the weakest triel bond, followed by the sp2-hybridized O atom or the sp3-hybridized N atom, and the sp3-hybridized O atom or the sp2-hybridized N atom engages in the strongest triel bond.	Nitrogen	24-25	Sp2 transcription factor	Homo sapiens	77-80
32875266-2	2020	The sp-hybridized O and N atoms form the weakest triel bond, followed by the sp2-hybridized O atom or the sp3-hybridized N atom, and the sp3-hybridized O atom or the sp2-hybridized N atom engages in the strongest triel bond.	Nitrogen	24-25	Sp3 transcription factor	Homo sapiens	106-109
32875266-2	2020	The sp-hybridized O and N atoms form the weakest triel bond, followed by the sp2-hybridized O atom or the sp3-hybridized N atom, and the sp3-hybridized O atom or the sp2-hybridized N atom engages in the strongest triel bond.	Nitrogen	24-25	Sp3 transcription factor	Homo sapiens	137-140
32875266-2	2020	The sp-hybridized O and N atoms form the weakest triel bond, followed by the sp2-hybridized O atom or the sp3-hybridized N atom, and the sp3-hybridized O atom or the sp2-hybridized N atom engages in the strongest triel bond.	Nitrogen	24-25	Sp2 transcription factor	Homo sapiens	166-169
32875266-2	2020	The sp-hybridized O and N atoms form the weakest triel bond, followed by the sp2-hybridized O atom or the sp3-hybridized N atom, and the sp3-hybridized O atom or the sp2-hybridized N atom engages in the strongest triel bond.	Nitrogen	121-122	Sp3 transcription factor	Homo sapiens	106-109
32875266-2	2020	The sp-hybridized O and N atoms form the weakest triel bond, followed by the sp2-hybridized O atom or the sp3-hybridized N atom, and the sp3-hybridized O atom or the sp2-hybridized N atom engages in the strongest triel bond.	Nitrogen	121-122	Sp3 transcription factor	Homo sapiens	106-109
32776892-3	2020	Analysis of serum transferrin (TRF) isoforms, as the classical procedure used to identify a CDG patient, enables to predict pathological steps in the N-linked glycosylation process.	Nitrogen	150-151	transferrin	Homo sapiens	31-34
32754990-0	2020	Nitrogen-containing flavonoid and their analogs with diverse B-ring in acetylcholinesterase and butyrylcholinesterase inhibition.	Nitrogen	0-8	acetylcholinesterase (Cartwright blood group)	Homo sapiens	71-91
32678601-0	2020	C-N and C-O Bonds Formation in Copper-Catalyzed/Mediated sp3 C-H Activation: Mechanistic Studies from Experimental and Computational Aspects.	Nitrogen	2-3	Sp3 transcription factor	Homo sapiens	57-60
33124337-13	2020	During the rainy season, the groundwater NO3- concentration in the Longfeng karst trough-valley was mainly due to the nitrification of NH4+ in precipitation and fertilizer as well as organic nitrogen in soil, whereas during the dry season, the groundwater NO3- concentration primarily originated from domestic sewage.	Nitrogen	191-199	NBL1, DAN family BMP antagonist	Homo sapiens	41-44
33124337-17	2020	In contrast, the groundwater NO3- concentration was mainly from domestic sewage (36.17%) in Longche karst trough-valley, and was followed by the nitrification of NH4+ from fertilizer and rainwater (23.5%), soil organic nitrogen (22.5%), and NO3- from rainwater and fertilizer (<10%).	Nitrogen	219-227	NBL1, DAN family BMP antagonist	Homo sapiens	29-32
32761757-5	2021	Dissolved inorganic nitrogen (DIN) amendment incubations and comparisons between our sampling campaigns suggested that denitrifier activity may be closely coupled with NO3 - availability.	Nitrogen	20-28	NBL1, DAN family BMP antagonist	Homo sapiens	168-171
32756490-5	2020	There are several investigations where biosensor measurement of NO3- and NO2- have given new insight into the functioning of nitrogen transformations in man-made and natural environments such as sediments and biofilms, but the biosensors have not become routine tools.	Nitrogen	125-133	NBL1, DAN family BMP antagonist	Homo sapiens	64-67
32687329-9	2020	Ligand 3 can be coordinated to FeCl2, and upon sequential halide abstraction, treatment with NaBH4, and exposure to an atmosphere of dinitrogen, the dinitrogen hydride complex [Fe(H)(NPP2"-iPr)(N2)][BPh4] (13) is isolated.	Nitrogen	133-143	ectonucleotide pyrophosphatase/phosphodiesterase 2	Homo sapiens	183-187
32753658-0	2020	Single-site pyrrolic-nitrogen-doped sp2-hybridized carbon materials and their pseudocapacitance.	Nitrogen	21-29	Sp2 transcription factor	Homo sapiens	36-39
32753658-1	2020	Integrating nitrogen species into sp2-hybridized carbon materials has proved an efficient means to improve their electrochemical performance.	Nitrogen	12-20	Sp2 transcription factor	Homo sapiens	34-37
32538218-8	2020	Our results indicated that the mouse antibody of CXCL4 treatment reduced the expression of urine creatinine and urea nitrogen in sepsis model.	Nitrogen	117-125	platelet factor 4	Mus musculus	49-54
32270793-3	2020	Herein, we demonstrate that infection by M. bovis BCG induces the remodeling of the N-glycomes of both human primary blood monocyte-derived macrophages (MDM) and macrophage-cell line THP1.	Nitrogen	84-85	GLI family zinc finger 2	Homo sapiens	183-187
32674688-8	2022	The highest selectivity to N2 (99.3) exhibited by the RhMo6/ZrAl-10 catalyst is proposed to be related to the high Rh dispersion (0.755) and to the presence of Lewis acid sites (oxygen vacancies) of the tetragonal ZrO2 modification that favour NO3 - adsorption through electrostatic interactions.	Nitrogen	27-29	NBL1, DAN family BMP antagonist	Homo sapiens	244-247
32415997-0	2020	One-bond 1 J(15 N,H) coupling constants at sp2 hybridized nitrogen of Schiff bases, enaminones and similar compounds.	Nitrogen	58-66	Sp2 transcription factor	Homo sapiens	43-46
32415997-2	2020	1 J(15 N,H) coupling constants for enaminones and NH-forms of intramolecularly hydrogen bonded Schiff bases as model compounds for sp2 hybridized nitrogen atoms are evaluated using density functional theory (DFT) to find the optimal functionals and basis sets.	Nitrogen	146-154	Sp2 transcription factor	Homo sapiens	131-134
32206788-2	2020	In plants, nitrogen (N) source for uptake and assimilation, mainly in the forms of nitrate (NO3-) and ammonium (NH4+) quantitatively dominates the anion and cation equilibrium and the pH balance in cells.	Nitrogen	11-19	NBL1, DAN family BMP antagonist	Homo sapiens	92-95
32407958-3	2020	The interactions between reactive oxygen species (ROS)/reactive nitrogen species (RNS) and innate immune receptors such as TLR2/4, NOD-like receptor, RAGE, and scavenger receptors are crucial pathological mechanisms that amplify brain damage during cerebral ischemic brain injury.	Nitrogen	64-72	toll like receptor 2	Homo sapiens	123-129
32346937-9	2020	Here, we report that inflammatory licensing leads to an enhanced PD-L1 cell surface expression and secretion, which are both accompanied by an increased posttranslational protein N-glycosylation.	Nitrogen	179-180	CD274 molecule	Sus scrofa	65-70
32346937-11	2020	In fact, promoting N-glycosylation in MSCs yielded increased PD-L1 levels.	Nitrogen	19-20	CD274 molecule	Sus scrofa	61-66
32346937-12	2020	We report for the first time that PD-L1 N-glycosylation plays a decisive role for its transport to the MSCs" cell surface and its subsequent secretion (in response to proinflammatory trigger).	Nitrogen	40-41	CD274 molecule	Sus scrofa	34-39
32849729-13	2020	As NO3 is a major source of nitrogen for plants and all plants may experience hypoxic and anoxic conditions owing to soil environmental factors, a significant global biogenic source of N2O may be its formation in plants via the proposed pathway.	Nitrogen	28-36	NBL1, DAN family BMP antagonist	Homo sapiens	3-6
32206788-5	2020	In addition, during N assimilation, carbon skeletons are required to synthesize amino acids, thus the combination of NO3- or NH4+ transport and assimilation results in different net charge and numbers of protons in plant cells.	Nitrogen	20-21	NBL1, DAN family BMP antagonist	Homo sapiens	117-120
32632429-0	2020	Hydrogen bonds and halogen bonds in complexes of carbones L C L as electron donors to HF and ClF, for L = CO, N2, HNC, PH3, and SH2.	Nitrogen	110-112	CLQTL1	Homo sapiens	93-96
32722234-0	2020	Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators.	Nitrogen	57-65	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	92-107
32722234-8	2020	The main modifications that have been performed during last few years to generate flavonoid and terpenoid derivatives, bearing nitrogen moieties, such as aliphatic, aromatic and heterocycle amine, amide, and related functional groups, as well as their P-gp, MRP1 and BCRP inhibitory activities are reviewed and discussed.	Nitrogen	127-135	ATP binding cassette subfamily B member 1	Homo sapiens	252-256
32722234-8	2020	The main modifications that have been performed during last few years to generate flavonoid and terpenoid derivatives, bearing nitrogen moieties, such as aliphatic, aromatic and heterocycle amine, amide, and related functional groups, as well as their P-gp, MRP1 and BCRP inhibitory activities are reviewed and discussed.	Nitrogen	127-135	ATP binding cassette subfamily B member 1	Homo sapiens	258-262
32722234-8	2020	The main modifications that have been performed during last few years to generate flavonoid and terpenoid derivatives, bearing nitrogen moieties, such as aliphatic, aromatic and heterocycle amine, amide, and related functional groups, as well as their P-gp, MRP1 and BCRP inhibitory activities are reviewed and discussed.	Nitrogen	127-135	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	267-271
32559180-5	2020	Interestingly, metabolite levels in these pathways correlated with clinical laboratory markers of inflammation (i.e., IL-6 and C-reactive protein) and renal function (i.e., blood urea nitrogen).CONCLUSIONIn conclusion, this initial observational study identified amino acid and fatty acid metabolism as correlates of COVID-19, providing mechanistic insights, potential markers of clinical severity, and potential therapeutic targets.FUNDINGBoettcher Foundation Webb-Waring Biomedical Research Award; National Institute of General and Medical Sciences, NIH; and National Heart, Lung, and Blood Institute, NIH.	Nitrogen	184-192	interleukin 6	Homo sapiens	118-122
32559180-5	2020	Interestingly, metabolite levels in these pathways correlated with clinical laboratory markers of inflammation (i.e., IL-6 and C-reactive protein) and renal function (i.e., blood urea nitrogen).CONCLUSIONIn conclusion, this initial observational study identified amino acid and fatty acid metabolism as correlates of COVID-19, providing mechanistic insights, potential markers of clinical severity, and potential therapeutic targets.FUNDINGBoettcher Foundation Webb-Waring Biomedical Research Award; National Institute of General and Medical Sciences, NIH; and National Heart, Lung, and Blood Institute, NIH.	Nitrogen	184-192	C-reactive protein	Homo sapiens	127-145
32709014-10	2020	Genome-wide association studies, employing questionnaire-based evaluations of individual chronotypes, revealed loci near clock genes and in the regions containing RGS16 and ALG10B, a gene encoding an enzyme involved in protein N-glycosylation.	Nitrogen	227-228	ALG10 alpha-1,2-glucosyltransferase B	Homo sapiens	173-179
32039447-2	2020	The N-terminal domain of beta-cleaved APP supports Cu/NO-dependent release of heparan sulfate (HS) from the glypican-1 (Gpc-1) proteoglycan.	Nitrogen	4-5	glypican 1	Mus musculus	108-118
32558566-0	2020	Co(III)-Catalyzed C-H Amidation of Nitrogen Containing Heterocycles with Dioxazolones under Mild Condition.	Nitrogen	35-43	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	0-7
32575989-0	2020	Bipentazole (N10): A Low-Energy Molecular Nitrogen Allotrope with High Intrinsic Stability.	Nitrogen	42-50	nuclear receptor subfamily 4 group A member 1	Homo sapiens	12-17
32039447-2	2020	The N-terminal domain of beta-cleaved APP supports Cu/NO-dependent release of heparan sulfate (HS) from the glypican-1 (Gpc-1) proteoglycan.	Nitrogen	4-5	glypican 1	Mus musculus	120-125
32575989-1	2020	In this letter, we report a crystal structure prediction and characterization of a molecular nitrogen allotrope N10 (bipentazole) using state-of-the-art computational methods.	Nitrogen	93-101	nuclear receptor subfamily 4 group A member 1	Homo sapiens	112-115
32656764-10	2021	Moreover, arsenate inhibited the activities of enzymes of the nitrogen metabolism (i.e. nitrate reductase, nitrite reductase, glutamine synthetase and glutamine 2-oxoglutarate aminotransferase) but increased the activity of glutamate dehydrogenase and NH4 + content.	Nitrogen	62-70	nitrate reductase [NADH]	Solanum lycopersicum	88-105
32774708-4	2020	RESULTS: The results indicated that the levels of serum creatinine, blood urea nitrogen and serum iron, the renal iron content, and the kidney injury score were significantly decreased in the hepcidin group (P<0.05).	Nitrogen	79-87	hepcidin antimicrobial peptide	Rattus norvegicus	192-200
32234597-15	2020	TG-n2 and TG alleviated the decrease of podocin protein expression and morphological injury of podocyte as screened by Western Blot and electron microscopic analysis.	Nitrogen	3-5	NPHS2 stomatin family member, podocin	Rattus norvegicus	40-47
32267563-1	2020	RATIONALE: The nitrogen isotopic ratio of nitrate (delta15 N-NO3 - value) is a critical parameter to understand nitrogen biogeochemical cycling in aquatic systems.	Nitrogen	15-23	NBL1, DAN family BMP antagonist	Homo sapiens	61-64
32267563-1	2020	RATIONALE: The nitrogen isotopic ratio of nitrate (delta15 N-NO3 - value) is a critical parameter to understand nitrogen biogeochemical cycling in aquatic systems.	Nitrogen	112-120	NBL1, DAN family BMP antagonist	Homo sapiens	61-64
32267563-2	2020	Current approaches to the determination of delta15 N-NO3 - values involve time-intensive handling procedures, use of toxic chemicals and complicated microbial incubation.	Nitrogen	51-52	NBL1, DAN family BMP antagonist	Homo sapiens	53-56
32765562-1	2020	As an important nitrogen source, nitrate (NO3 -) absorbed by plants is carried throughout the plant via short-distance distribution (cytoplasm to vacuole) and long-distance transportation (root to shoot), the two pathways that jointly regulate the content of NO3 - in plants.	Nitrogen	16-24	NBL1, DAN family BMP antagonist	Homo sapiens	42-45
32551569-9	2020	Realizing lack of information on the regulation of GSL biosynthesis and degradation mechanism, this review also includes those information along with their connection with crosstalks between various factors, such as light, sulfur metabolism, and nitrogen metabolism, with the GSL biosynthesis as means to provide a comprehensive reference for other crucifer species.	Nitrogen	246-254	cathepsin A	Homo sapiens	276-279
32657163-4	2022	Administration of CCl4 resulted in a marked increase in hepatic (aspartate aminotransferase, alanine transaminase, and alkaline phosphatase) and renal (blood urea nitrogen and creatinine) markers.	Nitrogen	163-171	C-C motif chemokine ligand 4	Rattus norvegicus	18-22
32664460-5	2020	Treatment with tunicamycin (Tm), the inhibitor of N-glycosylation of secreted glycoproteins, increased the transcript levels of SlBiP.	Nitrogen	50-51	BEL1-like homeodomain protein 2	Solanum lycopersicum	128-133
32864552-6	2020	The apparent molecular weight of TF is increased by N-linked glycosylation and, as expected, deglycosylation decreased the size of TF based on western blotting.	Nitrogen	52-53	coagulation factor III	Mus musculus	33-35
32432600-7	2020	The compound H2L is non-fluorescent; however, in the presence of CdII and PbII, the compound H2L is highly fluorescent with well-separated excitation and emission wavelengths, indicating that the metal ion is coordinated through phenolic oxygen and imine nitrogen of the Schiff base blocking the PET (Photoinduced Electron Transfer) process and stimulating the CHEF (Chelation Enhanced Fluorescence) process, to increase the fluorescence intensity of H2L.	Nitrogen	255-263	submaxillary gland androgen regulated protein 3B	Homo sapiens	74-78
32073833-2	2020	The reaction of the copper(I) complex of N,N,N",N"-tetramethypropylenediamine with a series of para-substituted nitrosobenzene derivatives leads to adducts in which the nitrosoarene (ArNO) is reduced by zero, one, or two electrons, akin to the isovalent species dioxygen, superoxide, and peroxide, respectively.	Nitrogen	41-77	cytohesin 2	Homo sapiens	183-187
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	cytohesin 2	Homo sapiens	114-118
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	cytohesin 2	Homo sapiens	139-143
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	cytohesin 2	Homo sapiens	139-143
32073833-6	2020	The 15N NMR signal disappears for the ArNO - species, establishing a unique diagnostic for the radical state.	Nitrogen	4-7	cytohesin 2	Homo sapiens	38-42
32614784-7	2021	The SARs analysis showed the structural difference including planar, quaternary nitrogen, and the peripheral functional groups at C-8, C-9, C-10, have strong effect on inhibition of TF activity, which provided effective methods to modify isoquinoline alkaloids for inhibiting TF activity.	Nitrogen	80-88	homeobox C10	Homo sapiens	140-144
32635182-6	2020	The results obtained clearly demonstrated that short-time (16s) exposure of ADSCs to nitrogen plasma accelerated proliferation of cells grown on the biomaterial containing FexOy/NPs catalysts and increased osteocalcin production by the cells cultured on the scaffold containing pure NPs.	Nitrogen	85-93	bone gamma-carboxyglutamate protein	Homo sapiens	206-217
32635192-2	2020	Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung injury driven by TNF-alpha, TGF-beta, ERK and HSP90.	Nitrogen	29-37	tumor necrosis factor	Mus musculus	114-123
32635192-2	2020	Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung injury driven by TNF-alpha, TGF-beta, ERK and HSP90.	Nitrogen	29-37	mitogen-activated protein kinase 1	Mus musculus	135-138
32348005-2	2020	Herein, we demonstrated that the introduction of two adjacent sp2 nitrogen atoms into a porphyrinic skeleton significantly enhanced its Bronsted basicity due to the repulsive interaction between two lone pairs on the nitrogen atoms.	Nitrogen	66-74	Sp2 transcription factor	Homo sapiens	62-65
32348005-2	2020	Herein, we demonstrated that the introduction of two adjacent sp2 nitrogen atoms into a porphyrinic skeleton significantly enhanced its Bronsted basicity due to the repulsive interaction between two lone pairs on the nitrogen atoms.	Nitrogen	217-225	Sp2 transcription factor	Homo sapiens	62-65
32329149-3	2020	The reaction condition and the structure of MDI-beta-CD-modified COF were optimized and characterized by X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectra, nitrogen adsorption/desorption (Brunauer-Emmett-Teller [BET]), and thermogravimetric analysis (TGA).	Nitrogen	174-182	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	48-55
32428845-11	2020	It is the ring nitrogen of tryptophan in GPx, a histidine in GAPDH and OxyR and a threonine in Prx.	Nitrogen	15-23	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	61-66
31558671-1	2020	Inv(11)(p15q23) found in myelodysplastic syndromes and acute myeloid leukemia leads to expression of a fusion protein consisting of the N-terminal of nucleoporin 98 (NUP98) and the majority of the lysine methyltransferase 2A (KMT2A) transcript.	Nitrogen	136-137	nucleoporin 98	Mus musculus	150-164
31558671-1	2020	Inv(11)(p15q23) found in myelodysplastic syndromes and acute myeloid leukemia leads to expression of a fusion protein consisting of the N-terminal of nucleoporin 98 (NUP98) and the majority of the lysine methyltransferase 2A (KMT2A) transcript.	Nitrogen	136-137	nucleoporin 98	Mus musculus	166-171
31558671-1	2020	Inv(11)(p15q23) found in myelodysplastic syndromes and acute myeloid leukemia leads to expression of a fusion protein consisting of the N-terminal of nucleoporin 98 (NUP98) and the majority of the lysine methyltransferase 2A (KMT2A) transcript.	Nitrogen	136-137	lysine (K)-specific methyltransferase 2A	Mus musculus	226-231
32331895-0	2020	Short communication: The essential role of N-glycosylation in the transport activity of bovine peptide transporter 2.	Nitrogen	43-44	solute carrier family 15 member 2	Bos taurus	95-116
31900478-8	2020	AMPKalpha1 consequently activated p38 mitogen-activated protein kinase (MAPK), c-Jun N-terminal kinase and cAMP responsive element binding protein (CREB) to regulate IL-10 production.	Nitrogen	85-86	protein kinase, AMP-activated, alpha 1 catalytic subunit	Mus musculus	0-10
31900478-8	2020	AMPKalpha1 consequently activated p38 mitogen-activated protein kinase (MAPK), c-Jun N-terminal kinase and cAMP responsive element binding protein (CREB) to regulate IL-10 production.	Nitrogen	85-86	interleukin 10	Mus musculus	166-171
32398320-5	2020	Besides DWF1, low N also upregulates other central BR biosynthesis genes including CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD), DWARF 4 (DWF4) and BRASSINOSTEROID-6-OXIDASE 2 (BR6OX2).	Nitrogen	18-19	Cytochrome P450 superfamily protein	Arabidopsis thaliana	83-118
32676089-7	2020	UAV-based remote sensing demonstrates that treatment T2 in both water 120 mm and N 180 kg ha-1 supply trials was most appropriate dosages for optimum uptake of water and N with high GY.	Nitrogen	81-82	Rho GTPase activating protein 45	Homo sapiens	90-94
32583581-6	2020	Remarkably, nitrate conversion and nitrogen selectivity are both close to 100% in an ultralow concentration of 10 mg L-1 , meeting drinking water standard.	Nitrogen	35-43	L1 cell adhesion molecule	Homo sapiens	117-120
32247143-4	2020	Results indicated that the main form of riverine nitrogen in this region was NO3-, constituting ~60% of the total nitrogen mass on average (total organic nitrogen ~37% & ammonium ~3%).	Nitrogen	49-57	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
32247143-4	2020	Results indicated that the main form of riverine nitrogen in this region was NO3-, constituting ~60% of the total nitrogen mass on average (total organic nitrogen ~37% & ammonium ~3%).	Nitrogen	114-122	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
32247143-4	2020	Results indicated that the main form of riverine nitrogen in this region was NO3-, constituting ~60% of the total nitrogen mass on average (total organic nitrogen ~37% & ammonium ~3%).	Nitrogen	114-122	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
32222508-5	2020	We confirmed denitrification producing di-nitrogen gas (N2) to be the primary NO3- removal pathway, but found that 6% of NO3- could be released as N2O under high NO3- concentrations and low amounts of bioavailable C, whereas DNRA rates tend to increase with the C amount.	Nitrogen	56-58	NBL1, DAN family BMP antagonist	Homo sapiens	78-81
32583487-5	2020	Analyzing sepsis-induced AKI rats and the cell model, our results revealed that miR-152-3p was upregulated in septic AKI patients and positively correlated with serum creatinine, urea nitrogen, interleukin 1beta (IL-1beta) and tumor necrosis factor alpha (TNF-alpha).	Nitrogen	184-192	microRNA 152	Rattus norvegicus	80-87
32456423-3	2020	Slow expulsion of dinitrogen (N2) was observed at room temperature to afford a ligand functionalized product via a [3+2] annulation, which can be mediated by a high-valent nitrene intermediate such as a CoIII iminyl (ArL)CoBr( N(C6H4-p-tBu)) or CoIV imido (ArL)CoBr(N(C6H4-p-tBu)) complex.	Nitrogen	18-28	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	203-208
32456423-3	2020	Slow expulsion of dinitrogen (N2) was observed at room temperature to afford a ligand functionalized product via a [3+2] annulation, which can be mediated by a high-valent nitrene intermediate such as a CoIII iminyl (ArL)CoBr( N(C6H4-p-tBu)) or CoIV imido (ArL)CoBr(N(C6H4-p-tBu)) complex.	Nitrogen	30-32	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	203-208
32456423-5	2020	Unlike (ArL)CoBr(N3(C6H4-p-tBu)), a series of alkyl azide-bound CoII analogues expel N2 only above 60  C, affording paramagnetic intermediates that convert to the corresponding Co-imine complexes via alpha-H-atom abstraction.	Nitrogen	85-87	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	64-68
32513738-7	2020	Despite this difference in affinities of GID4 for Nt-IGLW vs. Nt-PGLW, we found that the GID4-mediated Pro/N-degron pathway of the yeast Saccharomyces cerevisiae can target an Nt-IGLW-bearing protein for rapid degradation.	Nitrogen	50-51	glucose-induced degradation complex subunit VID24	Saccharomyces cerevisiae S288C	89-93
32655605-10	2020	Our results show that increased shoot and boll biomasses were correlated with a significant increase in the root system especially the shallow roots in the moderate N treatment (240 kg ha-1), leading to an increase in cotton seed yield.	Nitrogen	165-166	Rho GTPase activating protein 45	Homo sapiens	185-189
32453309-1	2020	The dynamics of the bimolecular nucleophilic substitution (SN2) reactions at nitrogen are less understood than those of their corresponding reactions at carbon.	Nitrogen	77-85	solute carrier family 38 member 5	Homo sapiens	59-62
32453309-2	2020	In this paper, we report an ab initio molecular dynamics approach to investigate the reaction mechanisms of the F- + NH2I SN2 reaction at nitrogen.	Nitrogen	138-146	solute carrier family 38 member 5	Homo sapiens	122-125
32508216-0	2021	Vac8 determines phagophore assembly site vacuolar localization during nitrogen starvation-induced autophagy.	Nitrogen	70-78	protein anchor VAC8	Saccharomyces cerevisiae S288C	0-4
32376684-3	2020	Here, we identified N-glycosylation sites in mouse EOGT and elucidated their molecular functions.	Nitrogen	20-21	EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase	Mus musculus	51-55
32022364-4	2020	Coordination of Co(II) ions into the porphyrin subunit followed by addition of appropriate monodentate nitrogen-based additives to function as axial ligands enable the radical carbene transfer reactions to styrene derivatives to occur exclusively through the cavity of the macrocycle to afford cyclopropane-linked rotaxanes in excellent 95% yield.	Nitrogen	103-111	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	16-22
32518194-3	2020	Consumption of NO3 - as the sole nitrogen source unexpectedly resulted in more rapid transfer of carbon to heterotrophs than when NH4 + was also provided, suggesting alterations in the form of carbon exchanged.	Nitrogen	33-41	NBL1, DAN family BMP antagonist	Homo sapiens	15-18
32478346-3	2020	These two CoIII products are characterized, showing a bent CoNO unit as the fate of the reduced nitrogen.	Nitrogen	96-104	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	10-15
32414922-7	2020	We found that altering the abundance of TGA1, an early N-responsive TF, perturbed the maximum rates of N-dose transcriptomic responses (V max), K m, as well as the rate of N-dose-responsive plant growth.	Nitrogen	55-56	bZIP transcription factor family protein	Arabidopsis thaliana	40-44
32414922-7	2020	We found that altering the abundance of TGA1, an early N-responsive TF, perturbed the maximum rates of N-dose transcriptomic responses (V max), K m, as well as the rate of N-dose-responsive plant growth.	Nitrogen	103-104	bZIP transcription factor family protein	Arabidopsis thaliana	40-44
32414922-7	2020	We found that altering the abundance of TGA1, an early N-responsive TF, perturbed the maximum rates of N-dose transcriptomic responses (V max), K m, as well as the rate of N-dose-responsive plant growth.	Nitrogen	103-104	bZIP transcription factor family protein	Arabidopsis thaliana	40-44
32414922-8	2020	We experimentally validated that MM-modeled N-dose-responsive genes included both direct and indirect TGA1 targets, using a root cell TF assay to detect TF binding and/or TF regulation genome-wide.	Nitrogen	44-45	bZIP transcription factor family protein	Arabidopsis thaliana	102-106
32546738-9	2020	Mutational analyses of key cysteine residues in TRPA1 (Cys421, Cys621, Cys641, and Cys665) and in TRPV1 (Cys258, Cys363, and Cys742) have suggested that multiple reactive oxygen and nitrogen species are intricately involved in activation of the channels via a broad range of modifications involving these cysteine residues.	Nitrogen	182-190	transient receptor potential cation channel, subfamily V, member 1	Mus musculus	98-103
32202031-6	2020	These include NifS and NifU, found primarily in aerobic species, suggesting that these genes are necessary for accommodating the high demand for Fe-S clusters during aerobic nitrogen fixation.	Nitrogen	174-182	iron-sulfur cluster assembly enzyme	Homo sapiens	23-27
32545500-8	2020	The adsorption and decomposition of CL-20 or FOX-7 on MgH2 could be attributed to the strong charge transfer between Mg atoms in the first layer of MgH2 (110) surface and oxygen as well as nitrogen atoms in the nitro-group of CL-20 or FOX-7 molecules.	Nitrogen	189-197	epithelial membrane protein 1	Homo sapiens	36-41
32146405-4	2020	The main NO3- sources included sewage/manure, chemical fertiliser and soil nitrogen.	Nitrogen	75-83	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
32277415-6	2020	The isotherms of adsorption and desorption of N2 confirm that the Cpa-AC adsorbent is mesopore material with a large surface area of 1040 m2 g-1.	Nitrogen	46-48	carboxypeptidase A1	Homo sapiens	66-69
32083736-8	2020	Shoot nitrogen concentrations suggested that plants create soils that increase nitrogen uptake, but that greater shoot nitrogen values increase herbivory and that the net effect of positive PSF and greater aboveground herbivory is less aboveground biomass.	Nitrogen	6-14	insulin like growth factor binding protein 7	Homo sapiens	190-193
32608796-2	2020	The results showed that when the autotrophic nitrogen removal and denitrification were operated stably for 67 days at an initial COD concentration of 60 mg L-1, the maximum nitrogen removal efficiency, the COD removal rate, and the nitrogen removal rate were 92.0%, 82.9%, and 2.3 kg (m3 d)-1, respectively.	Nitrogen	45-53	L1 cell adhesion molecule	Homo sapiens	156-159
32608796-2	2020	The results showed that when the autotrophic nitrogen removal and denitrification were operated stably for 67 days at an initial COD concentration of 60 mg L-1, the maximum nitrogen removal efficiency, the COD removal rate, and the nitrogen removal rate were 92.0%, 82.9%, and 2.3 kg (m3 d)-1, respectively.	Nitrogen	173-181	L1 cell adhesion molecule	Homo sapiens	156-159
32608796-2	2020	The results showed that when the autotrophic nitrogen removal and denitrification were operated stably for 67 days at an initial COD concentration of 60 mg L-1, the maximum nitrogen removal efficiency, the COD removal rate, and the nitrogen removal rate were 92.0%, 82.9%, and 2.3 kg (m3 d)-1, respectively.	Nitrogen	173-181	L1 cell adhesion molecule	Homo sapiens	156-159
32517158-7	2020	Mutation of the two N-glycosylation sites on  21-121 EMCN abolished its interaction with VEGFR2 and its function in VEGFR2 internalization.	Nitrogen	20-21	endomucin	Mus musculus	53-57
32714760-0	2020	DPAGT1-Mediated Protein N-Glycosylation Is Indispensable for Oocyte and Follicle Development in Mice.	Nitrogen	24-25	dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	Mus musculus	0-6
32714760-3	2020	Here, DPAGT1, the enzyme that catalyzes the first step of protein N-glycosylation, is identified to be indispensable for oocyte development in mice.	Nitrogen	66-67	dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	Mus musculus	6-12
32487741-8	2020	The ratio of C/N was linearly related with the concentrations of DCA and LCA and gene expression levels of ZO-1, occludin, and EGFR.	Nitrogen	15-16	epidermal growth factor receptor	Sus scrofa	127-131
32832863-8	2020	In HF, chronic beta-AR activity and production of reactive oxygen species and reactive nitrogen species provide two stress-induced mechanisms uncoupling RyR2 control, resulting in pathological diastolic SR Ca2+ leak.	Nitrogen	87-95	ryanodine receptor 2	Homo sapiens	153-157
32017353-9	2020	Furthermore, HBV encountered the Sec24A/Sec23B complex via an interaction that involved the N-terminal half of Sec24A and a di-arginine motif of its S domain, mirroring a novel ER export code.	Nitrogen	92-93	SEC24 homolog A, COPII coat complex component	Homo sapiens	33-39
32017353-9	2020	Furthermore, HBV encountered the Sec24A/Sec23B complex via an interaction that involved the N-terminal half of Sec24A and a di-arginine motif of its S domain, mirroring a novel ER export code.	Nitrogen	92-93	SEC24 homolog A, COPII coat complex component	Homo sapiens	111-117
32279742-10	2020	The antibiofilm activity of NFP-MWCNT and NFB-MWCNT was associated with their specific surface chemistry (due to the presence of N, F, P/B heteroatoms), and their nanosize.	Nitrogen	28-29	serine peptidase inhibitor, Kunitz type, 2	Rattus norvegicus	135-138
32124508-1	2020	The balance between nitrate respiration pathways, denitrification and dissimilatory nitrate (NO3 - ) reduction to ammonium (DNRA), determines whether bioavailable nitrogen is removed as N2 gas or recycled as ammonium.	Nitrogen	163-171	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
32124508-1	2020	The balance between nitrate respiration pathways, denitrification and dissimilatory nitrate (NO3 - ) reduction to ammonium (DNRA), determines whether bioavailable nitrogen is removed as N2 gas or recycled as ammonium.	Nitrogen	186-188	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
31342638-5	2020	Here, we show that NRT2.1 protein stability is also regulated in response to nitrogen nutrition availability.	Nitrogen	77-85	nitrate transporter 2:1	Arabidopsis thaliana	19-25
31558672-2	2020	Although it has been established that the FVIII binding site resides in the N-terminal D"-D3 domains of Von Willebrand Factor, detailed information about the amino acid regions that contribute to FVIII binding is still lacking.	Nitrogen	76-77	von Willebrand factor	Homo sapiens	104-125
32109361-1	2020	Medication-related osteonecrosis of the jaw (MRONJ) is a rare intraoral lesion that occurs in patients undergoing long-term and/or high-dose therapy with nitrogen-containing bisphosphonates, a RANKL inhibitor, antiangiogenic agents, or mTOR inhibitors.	Nitrogen	154-162	mechanistic target of rapamycin kinase	Homo sapiens	236-240
32336035-1	2020	The transcription factor, nuclear factor E2-related factor 2 (Nrf2), is highly sensitive to oxidative burst products, including reactive oxygen species (ROS) and reactive nitrogen species.	Nitrogen	171-179	NFE2 like bZIP transcription factor 2	Homo sapiens	26-60
32336035-1	2020	The transcription factor, nuclear factor E2-related factor 2 (Nrf2), is highly sensitive to oxidative burst products, including reactive oxygen species (ROS) and reactive nitrogen species.	Nitrogen	171-179	NFE2 like bZIP transcription factor 2	Homo sapiens	62-66
32295709-10	2020	Interleukin 6, monocyte chemotactic protein-1, and blood urea nitrogen levels and thrombin time were independently associated with increased glucagon-like peptide 1 levels.	Nitrogen	62-70	glucagon	Homo sapiens	141-164
32219694-4	2020	Activities of CYP enzymes were determined using the CYP-specific reactions: caffeine 3-N-demethylation (CYP1A2), diclofenac 4"-hydroxylation (CYP2C9), perazine N-demethylation (CYP2C19), bufuralol 1"-hydroxylation (CYP2D6), and testosterone 6beta-hydroxylation (CYP3A4).	Nitrogen	86-88	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	14-17
32219694-4	2020	Activities of CYP enzymes were determined using the CYP-specific reactions: caffeine 3-N-demethylation (CYP1A2), diclofenac 4"-hydroxylation (CYP2C9), perazine N-demethylation (CYP2C19), bufuralol 1"-hydroxylation (CYP2D6), and testosterone 6beta-hydroxylation (CYP3A4).	Nitrogen	86-88	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	52-55
32203567-7	2020	Additionally, treatment with either ICG-001 or E7386, which are both small molecule inhibitors of beta-catenin/CBP signaling, leads to increased transcriptional expression of fucosyltransferases FUT2 and FUT3, with a concomitant increase in EGFR N-glycan antennary fucosylation.	Nitrogen	246-247	fucosyltransferase 2	Homo sapiens	195-199
32486343-1	2020	: Reactive nitrogen species (RNS) are formed when there is an abnormal increase in the level of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) and/or by the uncoupled endothelial nitric oxide synthase (eNOS).	Nitrogen	11-19	nitric oxide synthase 2	Homo sapiens	130-161
32486343-1	2020	: Reactive nitrogen species (RNS) are formed when there is an abnormal increase in the level of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) and/or by the uncoupled endothelial nitric oxide synthase (eNOS).	Nitrogen	11-19	nitric oxide synthase 2	Homo sapiens	163-167
32486343-1	2020	: Reactive nitrogen species (RNS) are formed when there is an abnormal increase in the level of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) and/or by the uncoupled endothelial nitric oxide synthase (eNOS).	Nitrogen	11-19	nitric oxide synthase 3	Homo sapiens	193-226
32486343-1	2020	: Reactive nitrogen species (RNS) are formed when there is an abnormal increase in the level of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) and/or by the uncoupled endothelial nitric oxide synthase (eNOS).	Nitrogen	11-19	nitric oxide synthase 3	Homo sapiens	228-232
32301496-7	2020	SMIM1 was tagged with an opsin-derived N-glycosylation reporter at either the N- or C-terminus and synthesized in vitro using rabbit reticulocyte lysate supplemented with canine pancreatic microsomes as a source of ER membrane.	Nitrogen	39-40	small integral membrane protein 1	Canis lupus familiaris	0-5
32301496-8	2020	SMIM1 topology was then determined by assessing the N-glycosylation of its N- or C-terminal tags.	Nitrogen	52-53	small integral membrane protein 1	Canis lupus familiaris	0-5
32301496-8	2020	SMIM1 topology was then determined by assessing the N-glycosylation of its N- or C-terminal tags.	Nitrogen	75-76	small integral membrane protein 1	Canis lupus familiaris	0-5
32450796-0	2020	Probing contacts of inhibitor locked in transition states in the catalytic triad of DENV2 type serine protease and its mutants by 1H, 19F and 15 N NMR spectroscopy.	Nitrogen	86-87	coagulation factor II, thrombin	Homo sapiens	95-110
32528505-6	2020	Based on the observation in the double mutants fugu5-1 ppa1 and fugu5-1 ppa4 of more severe atrophy compared to fugu5-1, the nitrogen-dependent phenotype might be linked to PPi metabolism.	Nitrogen	125-133	pyrophosphorylase 1	Arabidopsis thaliana	55-59
32550602-4	2020	In this work, we report a strategy to photocatalytically fix nitrogen through simultaneous reduction and oxidation to produce NH4 + and NO3 - by W18O49 nanowires in pure water.	Nitrogen	61-69	NBL1, DAN family BMP antagonist	Homo sapiens	136-139
32444916-7	2020	The electronic spectra of the complexes of CX[4] with NO3, NO2, CO2, and N2) exhibit a blue-shift pick in comparison with the ones observed for the CX[4] molecule.	Nitrogen	73-75	NBL1, DAN family BMP antagonist	Homo sapiens	54-57
31112603-6	2020	We provide in silico, molecular dynamics and experimental data to support that CucWi-N (i) possesses high capability to target mortalin-p53 interaction and hnRNP-K proteins, (ii) triggers replicative senescence and inhibits metastatic potential of the cancer cells, and (iii) inhibits tumor progression and metastasis in vivo.	Nitrogen	85-86	tumor protein p53	Homo sapiens	136-139
32105927-2	2020	The nitrogen (N) isotopic enrichment factor (ep/s) is an important parameter to explain the N cycle and determine the proportional contribution of NO3- sources.	Nitrogen	4-12	NBL1, DAN family BMP antagonist	Homo sapiens	147-150
32269076-4	2020	The primate classical MHC class I allomorphs, Mamu-B*098 and Mamu-B*05104, are capable of binding the N-myristoylated 5-mer (C14-Gly-Gly-Ala-Ile-Ser) or 4-mer (C14-Gly-Gly-Ala-Ile) lipopeptides derived from the N-myristoylated SIV Nef protein, respectively, and of activating lipopeptide antigen-specific cytotoxic T lymphocytes.	Nitrogen	102-103	S100 calcium binding protein B	Homo sapiens	231-234
32508671-5	2020	MPO also mediates oxidative stress by promoting the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS), modulating the polarization and inflammation-related signaling pathways in microglia and neutrophils.	Nitrogen	109-117	myeloperoxidase	Homo sapiens	0-3
32250815-2	2020	This could lead to increased nitrate (NO3-) leaching when water scarcity affects the N-uptake capacity of trees and increases soil N availability due to early leaf senescence and higher litter input.	Nitrogen	85-86	NBL1, DAN family BMP antagonist	Homo sapiens	38-41
32269076-4	2020	The primate classical MHC class I allomorphs, Mamu-B*098 and Mamu-B*05104, are capable of binding the N-myristoylated 5-mer (C14-Gly-Gly-Ala-Ile-Ser) or 4-mer (C14-Gly-Gly-Ala-Ile) lipopeptides derived from the N-myristoylated SIV Nef protein, respectively, and of activating lipopeptide antigen-specific cytotoxic T lymphocytes.	Nitrogen	211-212	S100 calcium binding protein B	Homo sapiens	231-234
32432138-10	2020	Finally, in multivariate analysis, the risk of developing CRS-1 was correlated with age > 60 years, urea nitrogen at admission and 24 h-urine output (AUC 0.83, SE = 60.5% SP = 93%), while sNGAL was not significantly correlated.	Nitrogen	105-113	twist family bHLH transcription factor 1	Homo sapiens	58-63
32478253-2	2020	The presence of N2, CO, and H2 in the atmosphere caused formations of TiN, TiC, and TiH2 in the composites, respectively, together with evident microstructural changes that determined the mechanical properties (compressive strength, compressive modulus, and Vickers microhardness) and wettabilities of the composites after sintering.	Nitrogen	16-18	RuvB like AAA ATPase 2	Homo sapiens	84-88
32415176-6	2020	In particular, we observed that nitrogen doping of sp2-like carbons atoms can produce a bandgap modulation between semimetallic and semiconductor behavior.	Nitrogen	32-40	Sp2 transcription factor	Homo sapiens	51-54
32408549-6	2020	Nitric oxide (NO) is a fundamental signal molecule for N regulation, where nitrate reductase (NR) plays a central role in its synthesis.	Nitrogen	0-1	nitrate reductase 1	Arabidopsis thaliana	75-92
32455232-7	2020	TG-MS analysis results show that the thermal decomposition products of F2602/GAP/CL-20 are mainly C2H6, H2O, N2, and CO2.	Nitrogen	109-111	epithelial membrane protein 1	Homo sapiens	81-86
31794069-3	2020	The N-terminal specific labeling of bioactive peptides and proteins with the TA4C derivatives proceeds under mild reaction conditions in excellent conversion (angiotensin I: 92%, ribonuclease A: 90%).	Nitrogen	4-5	angiotensinogen	Homo sapiens	159-172
32303795-7	2020	A quantification limit of 11.3 NH4+mg L-1 and linear application range from up to 150 NH4+mg L-1 were obtained making it suitable for the expected concentrations of total ammonia nitrogen in human saliva.	Nitrogen	179-187	L1 cell adhesion molecule	Homo sapiens	38-41
32303795-7	2020	A quantification limit of 11.3 NH4+mg L-1 and linear application range from up to 150 NH4+mg L-1 were obtained making it suitable for the expected concentrations of total ammonia nitrogen in human saliva.	Nitrogen	179-187	L1 cell adhesion molecule	Homo sapiens	93-96
32054419-5	2020	Under nitrogen-starvation conditions, the Spt4-Spt5 complex derepresses ATG8 and ATG41 expression and upregulates bulk autophagy activity.	Nitrogen	6-14	SPT4 homolog, DSIF elongation factor subunit	Homo sapiens	42-46
32054419-5	2020	Under nitrogen-starvation conditions, the Spt4-Spt5 complex derepresses ATG8 and ATG41 expression and upregulates bulk autophagy activity.	Nitrogen	6-14	GABA type A receptor associated protein like 1	Homo sapiens	72-76
31960754-7	2020	These results provide new pharmacological evidence that ALP facilitates neuroprotection via prevention of neuronal oxidative stress and promotion of cell survival signaling pathways.Abbreviations: ABTS: 2,2"-azino-bis-(3-ethylbenzothiazoline-6-sulfonicacid); AD: Alzheimer"s disease; ALP: polysaccharide extracts isolated from Annona muricata leaves; ARE: antioxidant response element; DPPH: 1,1-diphenyl-picrylhydrazyl; DCFH-DA: 2",7"-dichlorofluorescin diacetate; ECL: electrochemiluminescence; ERK: extracellular regulated kinase; FBS: Fetal bovine serum; FITC: fluorescein isothiocyanate; FRAP: ferric reducing antioxidant power; HO-1: Heme oxygenase-1; JNK: c-jun N-terminal kinase; MAPKs: mitogen-activated protein kinases; MDA: malondialdehyde; MMP: mitochondrial membrane potential; MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazoliumbromide; NQO1: NAD(P)H:quinine oxidoreductase 1, Nrf2: nuclear factor-E2-related factor 2; PD: parkinson"s disease; PI3K: phosphatidylinositol-3kinase; PVDF: polyvinylidene difluoride; ROS: reactive oxygen species; SOD: Superoxidedismutase; TPTZ: tripydyltriazine.	Nitrogen	659-660	alopecia, recessive	Mus musculus	56-59
32277559-9	2020	In addition, incubation of PMN with N-Gel effectively reduced both TNF-alpha and IL-8 mRNA levels.	Nitrogen	29-30	tumor necrosis factor	Homo sapiens	67-76
32199305-2	2020	Compounds that have the 6R, 12aR configuration and terminal carboxylic acid group at the side chain arising from the piperazinedione nitrogen were potent PDE5 inhibitors, with compound 11 having almost equal potency to tadalafil and superior selectivity over PDE11, the most common off-target for tadalafil.	Nitrogen	133-141	phosphodiesterase 5A	Homo sapiens	154-158
32032660-12	2020	Moreover, cells exposed to A + N can influence neighboring cells in paracrine fashion, for instance, they shed ectodomain of COL17A1 protein and induce, in p53-dependent mode, the expression of gene for interleukin-7.	Nitrogen	31-32	collagen type XVII alpha 1 chain	Homo sapiens	125-132
32032660-12	2020	Moreover, cells exposed to A + N can influence neighboring cells in paracrine fashion, for instance, they shed ectodomain of COL17A1 protein and induce, in p53-dependent mode, the expression of gene for interleukin-7.	Nitrogen	31-32	tumor protein p53	Homo sapiens	156-159
32032660-12	2020	Moreover, cells exposed to A + N can influence neighboring cells in paracrine fashion, for instance, they shed ectodomain of COL17A1 protein and induce, in p53-dependent mode, the expression of gene for interleukin-7.	Nitrogen	31-32	interleukin 7	Homo sapiens	203-216
32087542-3	2020	The optimum C/N of 8 and HRT of 6 h for heterotrophic denitrification was obtained with NO3--N removal efficiency of 97.8% and 94.2%, respectively.	Nitrogen	14-15	NBL1, DAN family BMP antagonist	Homo sapiens	88-91
32032660-1	2020	Actinomycin D and nutlin-3a (A + N) activate p53, partly through induction of phosphorylation on Ser392.	Nitrogen	33-34	tumor protein p53	Homo sapiens	45-48
32032660-2	2020	The death of A549 cells induced by A + N morphologically resembles inflammation-inducing pyroptosis - cell destruction triggered by activated caspase-1.	Nitrogen	39-40	caspase 1	Homo sapiens	142-151
32032660-3	2020	The treatment with A + N (or camptothecin) strongly upregulated caspase-1 and its two activators: IFI16 and NLRP1, however, caspase-1 activation was not detected.	Nitrogen	23-24	caspase 1	Homo sapiens	64-73
32032660-3	2020	The treatment with A + N (or camptothecin) strongly upregulated caspase-1 and its two activators: IFI16 and NLRP1, however, caspase-1 activation was not detected.	Nitrogen	23-24	NLR family pyrin domain containing 1	Homo sapiens	108-113
32032660-3	2020	The treatment with A + N (or camptothecin) strongly upregulated caspase-1 and its two activators: IFI16 and NLRP1, however, caspase-1 activation was not detected.	Nitrogen	23-24	caspase 1	Homo sapiens	124-133
32032660-5	2020	The investigation of additional innate immunity elements revealed that A + N (or camptothecin) stimulated the expression of NLRX1, STING (stimulator of interferon genes) and two antiviral proteins, IFIT1 and IFIT3.	Nitrogen	75-76	NLR family member X1	Homo sapiens	124-129
32277559-9	2020	In addition, incubation of PMN with N-Gel effectively reduced both TNF-alpha and IL-8 mRNA levels.	Nitrogen	29-30	C-X-C motif chemokine ligand 8	Homo sapiens	81-85
31968125-0	2020	Phosphatidylethanolamine accelerates aggregation of the amyloidogenic N-terminal fragment of apoA-I.	Nitrogen	70-71	apolipoprotein A1	Homo sapiens	93-99
31968125-2	2020	Here, we found that phosphatidylethanolamine (PE) accelerates aggregation of the N-terminal 1-83 fragment of an amyloidogenic G26R variant of apoA-I on lipid membranes.	Nitrogen	81-82	apolipoprotein A1	Homo sapiens	142-148
32070740-1	2020	The so-called "H-fragment" of insulin is an extremely amyloidogenic double chain peptide consisting of the N-terminal parts of A-chain and B-chain linked by a disulfide bond between Cys-7A and Cys7B.	Nitrogen	107-108	insulin	Homo sapiens	30-37
31968125-5	2020	These results suggest that PE promotes aggregation of the amyloidogenic N-terminal fragment of apoA-I on lipid membranes by inducing hydrophobic membrane environments.	Nitrogen	72-73	apolipoprotein A1	Homo sapiens	95-101
32017069-4	2020	A mass spectrometry analysis revealed that IkappaBbeta phosphorylation sites are distributed in its C-terminal region, whereas IkappaBalpha phosphorylation sites are located in the N-terminal region.	Nitrogen	181-182	NFKB inhibitor alpha	Homo sapiens	127-139
32249421-5	2020	Higher leaf concentrations of NO3 - were observed in plants treated with 100% N-NO3 - , but they were still below tolerable limits for human health.	Nitrogen	30-31	NBL1, DAN family BMP antagonist	Homo sapiens	80-83
31883005-9	2020	Salacinol inhibited the processing glucosidase I/II, which are involved in the initial stage of N-linked glycosylation.	Nitrogen	96-97	mannosyl-oligosaccharide glucosidase	Homo sapiens	35-51
32017710-4	2020	RESULTS: Whole-exome sequencing within a precision oncology program identified an activating mutation (p.Asp769Tyr) in the catalytic domain of the ERBB2 receptor tyrosine kinase in a patient with schwannomatosis-associated N/S HNST, and targeted treatment with the small-molecule ERBB inhibitor lapatinib led to prolonged clinical benefit and a lasting radiographic and metabolic response.	Nitrogen	223-224	erb-b2 receptor tyrosine kinase 2	Homo sapiens	147-152
32017710-4	2020	RESULTS: Whole-exome sequencing within a precision oncology program identified an activating mutation (p.Asp769Tyr) in the catalytic domain of the ERBB2 receptor tyrosine kinase in a patient with schwannomatosis-associated N/S HNST, and targeted treatment with the small-molecule ERBB inhibitor lapatinib led to prolonged clinical benefit and a lasting radiographic and metabolic response.	Nitrogen	223-224	epidermal growth factor receptor	Homo sapiens	147-151
32249421-8	2020	Although treatment with 100% N-NO3 - favored higher mineral concentrations in lettuce leaves, the addition of 25% N-NH4 + allowed fresh mass production with the lowest NO3 - concentrations.	Nitrogen	29-30	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
32249421-11	2020	PRACTICAL APPLICATION: We demonstrate a direct link between the constitution of nutrient solution with nitrate accumulation by hydroponic lettuce and indicate the best source of N as well as the concentration of Mn to healthy reduction of NO3 - consumption by humans and the maintenance of plant productivity.	Nitrogen	20-21	NBL1, DAN family BMP antagonist	Homo sapiens	239-242
32475187-6	2020	Levels of 24-hour urinary microalbumin, creatinine, blood urea nitrogen, collagens I, III, and IV, alpha-smooth muscle actin, transforming growth factor-beta1, and Smad3 in Astragalus polysaccharide groups (all doses) were significantly lower than those in the model group.	Nitrogen	63-71	SMAD family member 3	Rattus norvegicus	164-169
31863529-5	2020	Based on the molecular docking scores and interactions, one can attribute the binding stability of Gid4 with degrons, to peptides of length six up to eight from the N-terminal.	Nitrogen	165-166	glucose-induced degradation complex subunit VID24	Saccharomyces cerevisiae S288C	99-103
31912134-9	2020	Cytoplasmic NAD(P)-dependent 10-formyl-tetrahydrofolate dehydrogenase (Aldh1/1) and mitochondrial NAD(P)-dependent 10-formyl-tetrahydrofolate dehydrogenase (Aldh1/2) , genes responsible for the catabolism of 10-formylTHF, were very weakly expressed in PP, low in livers of F and N, and reached the significantly higher adult levels in J.	Nitrogen	12-13	aldehyde dehydrogenase 1 family, member L1	Rattus norvegicus	29-69
31912134-6	2020	The abundance of mitochondrial monofunctional 10-formyl-tetrahydrofolate synthetase (Mthfd1l) mRNA was significantly higher in placenta (PP) and F liver than in liver of N or J.	Nitrogen	96-97	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	Rattus norvegicus	85-92
32027933-1	2020	Activation of the integrated stress response (ISR), alterations in nucleo-cytoplasmic (N/C) transport and changes in alternative splicing regulation are all common traits of the pathogenesis of Amyotrophic Lateral Sclerosis (ALS).	Nitrogen	87-88	superoxide dismutase 1	Homo sapiens	194-223
32216867-5	2020	A 1021 argI1 null mutant lacked arginase activity and grew at a drastically reduced rate with arginine as sole nitrogen source.	Nitrogen	111-119	arginase	Sinorhizobium meliloti 1021	7-12
32067292-5	2020	The scFv-h3D6 generated by our research group derives from this monoclonal antibody, which targets the N-terminal of the Abeta peptide and recognizes monomers, oligomers and fibrils.	Nitrogen	103-104	immunglobulin heavy chain variable region	Homo sapiens	4-8
32027933-9	2020	This suggests that changes in the nuclear localization of the UsnRNP complexes induced by mutant ALS proteins are uncoupled from ISR activation, and that defects in the N/C trafficking of UsnRNPs might play a role in ALS pathogenesis.	Nitrogen	66-67	superoxide dismutase 1	Homo sapiens	97-100
32067292-5	2020	The scFv-h3D6 generated by our research group derives from this monoclonal antibody, which targets the N-terminal of the Abeta peptide and recognizes monomers, oligomers and fibrils.	Nitrogen	103-104	histocompatibility 2, class II antigen A, beta 1	Mus musculus	121-126
32321988-4	2020	The results showed that FT1 exhibited the greatest nutrient accumulation speed for both the average (5.81, 1.22, and 5.74 kg ha-1 of N, P2O5, and K2O, respectively) and the maximum (6.31, 1.44, and 6.24 kg ha-1 of N, P2O5, and K2O, respectively) during the fast accumulation period.	Nitrogen	133-134	AKT interacting protein	Homo sapiens	24-27
31811679-10	2020	Importantly, results of mutant protoplast-based assays and in planta analysis using NIGT1 overexpression in the spx1 spx2 double mutant indicated that the NIGT1-SPX-PHR cascade mediates nitrogen status-responsive regulation of phosphate uptake and starvation signaling.	Nitrogen	186-194	MYC binding protein 2	Homo sapiens	165-168
32000154-9	2020	However, channeled texture of the both N-PEEK and N-PEEK/B-nHAp samples enhanced Col1a1 mRNA expression and collagen secretion in addition to increased alkaline phosphatase (ALP) activity when compared to other groups.	Nitrogen	39-40	collagen, type I, alpha 1	Mus musculus	81-87
32000154-9	2020	However, channeled texture of the both N-PEEK and N-PEEK/B-nHAp samples enhanced Col1a1 mRNA expression and collagen secretion in addition to increased alkaline phosphatase (ALP) activity when compared to other groups.	Nitrogen	50-51	collagen, type I, alpha 1	Mus musculus	81-87
31840341-4	2020	RESULTS: In the 15 NH4 NO3 treatment, the 15 N signature of NO emitted from the foot of the hillslope (Lower site) was similar to that of the NH4 + pool, indicating predominant autotrophic nitrification for NO formation.	Nitrogen	19-20	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
31840341-5	2020	In the NH4 15 NO3 treatment, the 15 N enrichment of NO was smaller than that of the NO3 - pool, suggesting minor contribution of denitrification to NO production (~15%).	Nitrogen	7-8	NBL1, DAN family BMP antagonist	Homo sapiens	14-17
32426328-0	2020	Efficient N-Glycosylation of the Heavy Chain Tailpiece Promotes the Formation of Plant-Produced Dimeric IgA.	Nitrogen	10-11	CD79a molecule	Homo sapiens	104-107
32426328-7	2020	Our data demonstrate that N-glycosylation engineering is a suitable strategy to promote the formation of dimeric IgA variants in plants.	Nitrogen	26-27	CD79a molecule	Homo sapiens	113-116
32321988-4	2020	The results showed that FT1 exhibited the greatest nutrient accumulation speed for both the average (5.81, 1.22, and 5.74 kg ha-1 of N, P2O5, and K2O, respectively) and the maximum (6.31, 1.44, and 6.24 kg ha-1 of N, P2O5, and K2O, respectively) during the fast accumulation period.	Nitrogen	214-215	AKT interacting protein	Homo sapiens	24-27
32041787-5	2020	Our data support that surface N-glycans likely facilitate the initial interaction of bacteria with monocytes and co-operate with CD18 integrins in trans to promote internalization of bacteria.	Nitrogen	30-31	integrin beta 2	Mus musculus	129-133
32426269-0	2020	Heterogeneities of Site-Specific N-Glycosylation in HCC Tumors With Low and High AFP Concentrations.	Nitrogen	33-34	alpha fetoprotein	Homo sapiens	81-84
32326313-5	2020	The temperature of 37  C was chosen to resemble human body temperature, and as under physiological conditions, albumin is in a non-denatured N conformation.	Nitrogen	141-142	albumin	Homo sapiens	111-118
31981873-2	2020	The oxygen-17 excess of nitrate (Delta17O(NO3-)) can be used to reveal the relative importance of nitrate formation pathways and get more insight into reactive nitrogen chemistry.	Nitrogen	160-168	NBL1, DAN family BMP antagonist	Homo sapiens	42-45
32316603-4	2020	N-linked glycosylation occurs in the endoplasmic reticulum (ER) lumen by a membrane associated enzyme complex called the oligosaccharyltransferase (OST).	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	148-151
32316603-12	2020	Both human OST complexes, OST-A (with STT3A) and OST-B (containing STT3B), are involved in the N-linked glycosylation of proteins in the ER.	Nitrogen	95-96	solute carrier family 51 subunit beta	Homo sapiens	49-54
32316603-9	2020	This review explains the most recent high-resolution structures of OST determined thus far and the mechanistic implication of N-linked glycosylation throughout all domains of life.	Nitrogen	126-127	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	67-70
32316603-15	2020	However, we still lack an understanding of the independent role of each eukaryotic OST subunit in N-linked glycosylation or in the stabilization of the enzyme complex.	Nitrogen	98-99	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	83-86
32316603-12	2020	Both human OST complexes, OST-A (with STT3A) and OST-B (containing STT3B), are involved in the N-linked glycosylation of proteins in the ER.	Nitrogen	95-96	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	11-14
32107165-0	2020	Identification of C10 nitrogen-containing aporphines with dopamine D1 versus D5 receptor selectivity.	Nitrogen	22-30	homeobox C10	Homo sapiens	18-21
32227905-1	2020	A copper-catalyzed approach was disclosed for C(sp3)-C(sp2) bond formation via an alpha-arylation of carbonyl, and the subsequent oxidative dehydrogenation coupling occurred to form a C(sp3)-N bond, wherein O2 served as a green oxidant.	Nitrogen	191-192	Sp2 transcription factor	Homo sapiens	53-58
32237752-2	2020	The reaction proceeds by the condensation of two molecules of fumaronitrile and one molecule of 1,3-diketone in a remarkable process that involves the cleavage of one C(sp3)-C(sp2) bond in 1,3-diketones and the formation of one carbon-nitrogen bond and four carbon-carbon bonds to construct both the aryl and pyrrole rings of the indole in one step.	Nitrogen	235-243	Sp2 transcription factor	Homo sapiens	174-179
32162518-5	2020	Thus, going from the sp3-hybrid lone pair in common sulfonamides to the sp-like lone pair in the smallest Paquette"s sultam resulted in an increase in S-N bond length by ca.	Nitrogen	153-154	Sp3 transcription factor	Homo sapiens	21-24
32318262-9	2020	By integrated analysis of both omic data, we found that in response to radiation insult, nitrogen metabolism, glutathione metabolism, arachidonic acid metabolism, and glycolysis or gluconeogenesis may be dysregulated due to p53.	Nitrogen	89-97	tumor protein p53	Homo sapiens	224-227
32293409-7	2020	Postoperative exogenous ALB infusion positively correlated with blood urea nitrogen, creatinine, complication grade, postoperative intraperitoneal hemorrhage and pancreatic fistula.	Nitrogen	75-83	albumin	Homo sapiens	24-27
32216372-3	2020	SIFSIX-23-Cu exhibits reversible switching between non-porous (beta1) and several porous (alpha, gamma1, gamma2 and gamma3) phases triggered by exposure to N2, CO2 or H2O.	Nitrogen	156-158	tryptophanyl-tRNA synthetase 1	Homo sapiens	97-122
31796347-4	2020	Furthermore, the nitrogen loss significantly decreased from 40.00%-14.70 % in the treatment added with semi-coke due to less emission of NH3 and much more transformation of NH4+-N to NO3--N by nitrification, which could be explained by the increasing abundance of ammonia-oxidizing bacteria and archaea at the late composting stage and drastic shift of the microbial community like Chloroflexi, Firmicutes and Actinobacteria.	Nitrogen	17-25	NBL1, DAN family BMP antagonist	Homo sapiens	183-186
32004600-0	2020	Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression.	Nitrogen	56-71	interleukin 6	Homo sapiens	13-17
32004600-0	2020	Silencing of IL-6 and STAT3 by siRNA loaded hyaluronate-N,N,N-trimethyl chitosan nanoparticles potently reduces cancer cell progression.	Nitrogen	56-71	signal transducer and activator of transcription 3	Homo sapiens	22-27
32004600-3	2020	In the present study, we generated the active-targeted hyaluronate (HA) recoated N, N, N-trimethyl chitosan (TMC) nanoparticles (NPs) to deliver IL-6- and STAT3-specific small interfering RNAs (siRNAs) to the CD44-expressing cancer cells.	Nitrogen	81-82	interleukin 6	Homo sapiens	145-149
32004600-3	2020	In the present study, we generated the active-targeted hyaluronate (HA) recoated N, N, N-trimethyl chitosan (TMC) nanoparticles (NPs) to deliver IL-6- and STAT3-specific small interfering RNAs (siRNAs) to the CD44-expressing cancer cells.	Nitrogen	84-85	interleukin 6	Homo sapiens	145-149
32320937-4	2020	The results showed that in comparison with the non-promoted monometallic Ni/CCFA catalyst, the bimetallic Ni-Re/CCFA catalyst displayed a superior activity, which could achieve 99.55% of CO2 conversion and 70.27% of CH4 selectivity under the condition of 400  C, 2000 h-1, 1 atm and H2:CO2:N2 = 4:1:0.5, possibly owing to the higher Ni dispersion and more active sites in Ni-Re/CCFA.	Nitrogen	290-292	COP9 signalosome subunit 4	Drosophila melanogaster	216-219
31945541-8	2020	These results could be useful in adjusting the denitrification of nitrogen contaminants at the genetic level, especially in mitigating the influence of discharge of NO3--N on the process of groundwater restoration.	Nitrogen	66-74	NBL1, DAN family BMP antagonist	Homo sapiens	165-168
32087767-3	2020	With the use of a small interfering RNA (siRNA)-mediated approach for selective downregulation of the four Arg/N-degron-dependent ubiquitin ligases, UBR1, UBR2, UBR4, and UBR5, we demonstrated decreased cell migration and proliferation and increased spontaneous apoptosis in cancer cells.	Nitrogen	37-38	ubiquitin protein ligase E3 component n-recognin 5	Mus musculus	171-175
32236264-1	2020	In this work, the origin of the singlet and triplet exciton-induced degradation of host materials with C(sp2)-N(sp3) bonds around nitrogen (carbazoles, acridines, etc.	Nitrogen	130-138	Sp2 transcription factor	Homo sapiens	103-108
32236264-3	2020	The results reveal that molecules (employed in OLEDs) with basic units containing C(sp2)-N(sp3) bonds (nitrogen connected to carbon in a triangular fashion) have a natural tendency to fragment at the C-N bond through an S1/S0 conical intersection (CI).	Nitrogen	89-90	Sp2 transcription factor	Homo sapiens	82-87
32236264-3	2020	The results reveal that molecules (employed in OLEDs) with basic units containing C(sp2)-N(sp3) bonds (nitrogen connected to carbon in a triangular fashion) have a natural tendency to fragment at the C-N bond through an S1/S0 conical intersection (CI).	Nitrogen	103-111	Sp2 transcription factor	Homo sapiens	82-87
32138918-3	2020	Herein, we developed optical sensors for DBH that include the following: (i) a ratiometric fluorescence sensor that hybridizes the bovine serum albumin (BSA)-gold nanoclusters (BSA-AuNCs) and nitrogen doped carbon dots (N-CDs).	Nitrogen	192-200	dopamine beta-hydroxylase	Bos taurus	41-44
32608686-2	2020	The finding indicated that in an intermittent operation mode, the average concentration of total nitrogen and ammonia nitrogen in the effluent could reach 1.05 mg L-1 and 0.54 mg L-1, and the average removal rate was 94.77% and 93.30%, respectively.	Nitrogen	97-105	L1 cell adhesion molecule	Homo sapiens	163-166
32608686-2	2020	The finding indicated that in an intermittent operation mode, the average concentration of total nitrogen and ammonia nitrogen in the effluent could reach 1.05 mg L-1 and 0.54 mg L-1, and the average removal rate was 94.77% and 93.30%, respectively.	Nitrogen	97-105	L1 cell adhesion molecule	Homo sapiens	179-182
32608686-2	2020	The finding indicated that in an intermittent operation mode, the average concentration of total nitrogen and ammonia nitrogen in the effluent could reach 1.05 mg L-1 and 0.54 mg L-1, and the average removal rate was 94.77% and 93.30%, respectively.	Nitrogen	118-126	L1 cell adhesion molecule	Homo sapiens	163-166
32608686-2	2020	The finding indicated that in an intermittent operation mode, the average concentration of total nitrogen and ammonia nitrogen in the effluent could reach 1.05 mg L-1 and 0.54 mg L-1, and the average removal rate was 94.77% and 93.30%, respectively.	Nitrogen	118-126	L1 cell adhesion molecule	Homo sapiens	179-182
32167295-3	2020	The chemical structure of these compounds, deduced from spectroscopic techniques, was in accordance with coordination of the silver fragments "AgL" to nitrogen atoms of the phosphazene ring, whereby their number n depends on the molar ratio used.	Nitrogen	151-159	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	143-146
32272552-1	2020	Dehydrodolichyl diphosphate synthase (DHDDS) is required for protein N-glycosylation in eukaryotic cells.	Nitrogen	69-70	dehydrodolichyl diphosphate synthase	Mus musculus	0-36
32272552-1	2020	Dehydrodolichyl diphosphate synthase (DHDDS) is required for protein N-glycosylation in eukaryotic cells.	Nitrogen	69-70	dehydrodolichyl diphosphate synthase	Mus musculus	38-43
32255892-7	2020	Although maize yield response to fertilizer differed with geographic location; on average, maize yield response to nitrogen (N), phosphorus (P) and potassium (K) were respectively 2.4, 1.6 and 0.2 t ha-1 in Nigeria, 2.3, 0.9 and 0.2 t ha-1 in Ethiopia, and 1.5, 0.8 and 0.2 t ha-1 in Tanzania.	Nitrogen	115-123	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	199-203
32120074-0	2020	Extensive investigation of benzylic N-containing substituents on the pyrrolopyrimidine skeleton as Akt inhibitors with potent anticancer activity.	Nitrogen	36-37	AKT serine/threonine kinase 1	Homo sapiens	99-102
31726481-4	2020	Our objectives were: 1) to describe a pheochromocytoma crisis 2) to investigate in vivo myocardial depressant activities for the N-terminal 1-76 Chromogranin A-derived peptide, Vasostatin-I.	Nitrogen	129-130	chromogranin A	Homo sapiens	145-159
31584203-0	2020	Hypoxia modulates stem cell properties and induces EMT through N-glycosylation of EpCAM in breast cancer cells.	Nitrogen	63-64	epithelial cell adhesion molecule	Homo sapiens	82-87
32023208-2	2020	ARMC5 is ubiquitously expressed and encodes a protein which contains a N-terminal Armadillo repeat domain and a C-terminal BTB (Bric-a-Brac, Tramtrack, Broad-complex) domain, both docking platforms for numerous proteins.	Nitrogen	71-72	armadillo repeat containing 5	Homo sapiens	0-5
31584203-3	2020	But the role of N-glycosylation in EpCAM in tumor aggressiveness is not clear.	Nitrogen	16-17	epithelial cell adhesion molecule	Homo sapiens	35-40
31584203-4	2020	Here, we evaluated the role of N-glycosylation of EpCAM in stemness and epithelial-mesenchymal transition (EMT) characteristics.	Nitrogen	31-32	epithelial cell adhesion molecule	Homo sapiens	50-55
31584203-6	2020	Knockdown of EpCAM and mutation of N-glycosylation of EpCAM maintained in severe hypoxia lead to a significant reduction of stemness/EMT markers.	Nitrogen	35-36	epithelial cell adhesion molecule	Homo sapiens	54-59
31733013-8	2020	N-terminal propeptides of type I collagen (P1NP) and alkaline phosphatase (ALP) showed a negative association with BMD at three sites in men and total lumbar BMD in women, whereas in the femur neck and total hip in women, the relationship was only found for P1NP with total hip.	Nitrogen	0-1	alkaline phosphatase, placental	Homo sapiens	53-73
31733013-8	2020	N-terminal propeptides of type I collagen (P1NP) and alkaline phosphatase (ALP) showed a negative association with BMD at three sites in men and total lumbar BMD in women, whereas in the femur neck and total hip in women, the relationship was only found for P1NP with total hip.	Nitrogen	0-1	alkaline phosphatase, placental	Homo sapiens	75-78
31584203-7	2020	In addition, we found that N-glycosylation of EpCAM is a crucial factor during this process.	Nitrogen	27-28	epithelial cell adhesion molecule	Homo sapiens	46-51
31917875-4	2020	Magnocellular vasopressin (VP) neurons respond directly to hypertonic stimulation with membrane depolarization, which is triggered by cell shrinkage-induced opening of N terminal-truncated TRPV1 channels.	Nitrogen	168-169	arginine vasopressin	Homo sapiens	14-25
31986066-3	2020	Two particular variants, P119L and P132L, had severe reduction in a level of N-linked glycosylation when compared with wild-type PTH1R, whereas the other 2 showed modest alteration.	Nitrogen	77-78	parathyroid hormone 1 receptor	Homo sapiens	129-134
32004914-5	2020	In this study NO3- was added to supplement the insufficient NOx- to enhance Fe(III) regeneration and remove nitrogen successively.	Nitrogen	108-116	NBL1, DAN family BMP antagonist	Homo sapiens	14-17
31954161-3	2020	We showed that CYP2J2 significantly decreased I/R-induced upregulation of blood urea nitrogen and serum creatinine and enhanced autophagy during I/R treatment.	Nitrogen	85-93	cytochrome P450, family 2, subfamily j, polypeptide 4	Rattus norvegicus	15-21
31911540-6	2020	We demonstrate that 5" fusion partners mainly promote canonical oncogenic BRAF activity by replacing the auto-inhibitory N-terminal region.	Nitrogen	121-122	B-Raf proto-oncogene, serine/threonine kinase	Homo sapiens	74-78
31713923-4	2020	Different mutations of GFP-CENH3 demonstrated that CENH3-Thr4 in the N terminus was needed for the deposition as a positive phosphorylation site and the last five amino acids in the C terminus are necessary for deposition.	Nitrogen	29-30	centromeric histone H3	Zea mays	51-56
31929398-15	2020	The AUC ratios of norbuprenorphine and norbuprenorphine glucuronide to buprenorphine, a measure of CYP3A mediated N-demethylation, were 1.89, 1.84, and 1.33 during the 1 and 2, 3 trimesters, and postpartum, respectively.	Nitrogen	114-115	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	99-104
32004914-7	2020	Consequently, nitrogen removal of the digester with an initial total nitrogen of 1036.7 mg/L reached 90.1% after 98-day operation, much higher than that of control (41.6%) without NO3- addition.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	180-183
32118414-1	2020	Electrochemical conversion of nitrate (NO3-) into ammonia (NH3) recycles nitrogen and offers a route to the production of NH3, which is more valuable than dinitrogen gas.	Nitrogen	73-81	NBL1, DAN family BMP antagonist	Homo sapiens	39-42
32440468-3	2020	Herein, a new form of stable all-nitrogen molecular crystals consisting of only bispentazole N10 molecules with exceedingly high energy density is predicted.	Nitrogen	33-41	nuclear receptor subfamily 4 group A member 1	Homo sapiens	93-96
32035902-0	2020	Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.	Nitrogen	20-21	calcitonin receptor	Homo sapiens	0-19
32273875-5	2020	Production of the corresponding recombinant FVIII mutants or light chains indicated that removal of the N-linked glycosylation site at N2118 is sufficient to abrogate in vitro the activation of FVIII-specific CD4+ T cells by human monocyte-derived dendritic cells.	Nitrogen	104-105	CD4 molecule	Homo sapiens	209-212
31691474-6	2020	The experimental studies and DFT calculations reveal that the high performance of the Co@FLG is mainly attributed to its great O2 absorptivity endowed by the abundant Co-Nx and pyridinic-N in the FLG shell and the strong electron-donating ability from the Co ND core to the FLG shell to elevate the eg-orbital energy of Co(II) and lower the activation energy for breaking the O=O/O-O bonds.	Nitrogen	177-188	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	320-326
32050172-8	2020	The improved performance of MN-BCNT is attributed to the improved electrical conductivity due to nitrogen doping and availability of significant active sites owing to length shortening.	Nitrogen	97-105	craniofacial development protein 1	Homo sapiens	31-35
32039437-4	2020	Here, we report the crystal structure of the HECT domain of UBE3C (amino acids (aa) 744-1083) with an additional fifty N-terminal amino acids (aa 693-743) at 2.7 A, along with multiple in vitro ubiquitination assays to understand its enzymatic activity.	Nitrogen	119-120	ubiquitin protein ligase E3C	Homo sapiens	60-65
32084312-2	2020	In this study, a fast photochemical renoxification rate of adsorbed HNO3/NO3- to active nitrogen species (HONO, NO and NO2) was detected on real urban PM2.5, and sulfate was found to play a key role in this process.	Nitrogen	88-96	NBL1, DAN family BMP antagonist	Homo sapiens	68-76
32084312-6	2020	This work implies that sulfate will have important implications in the atmospheric nitrogen cycling by accelerating the release of nitrogen oxides from photochemical renoxification of HNO3/NO3- adsorbed on ambient particulates, and thus can raise major environmental problems.	Nitrogen	83-91	NBL1, DAN family BMP antagonist	Homo sapiens	185-188
32084312-6	2020	This work implies that sulfate will have important implications in the atmospheric nitrogen cycling by accelerating the release of nitrogen oxides from photochemical renoxification of HNO3/NO3- adsorbed on ambient particulates, and thus can raise major environmental problems.	Nitrogen	131-139	NBL1, DAN family BMP antagonist	Homo sapiens	185-188
32001135-2	2020	We recently reported the synthesis of a new series of 2-O-butyl-8-oxoadenines substituted at the 9-position with various linkers and N-heterocycles, and showed that TLR7/8 selectivity, potency and cytokine induction could be modulated by varying the alkyl linker length and the N-heterocyclic ring.	Nitrogen	133-134	toll like receptor 7	Homo sapiens	165-171
32001135-2	2020	We recently reported the synthesis of a new series of 2-O-butyl-8-oxoadenines substituted at the 9-position with various linkers and N-heterocycles, and showed that TLR7/8 selectivity, potency and cytokine induction could be modulated by varying the alkyl linker length and the N-heterocyclic ring.	Nitrogen	278-279	toll like receptor 7	Homo sapiens	165-171
31810697-5	2020	We also described that N fertilizer alters the Cd exchange capacity and the bio-available Cd content in soil; regulates nitric oxide induced divalent cation gene expression of Nramp1, HMA2, and IRT1; and changes cell wall isolation, chelation capacity, and oxidative resistance to regulate Cd accumulation in plants.	Nitrogen	23-24	solute carrier family 11 member 1	Homo sapiens	176-182
32044549-3	2020	The aim of the present study was to determine the effects of the carbon/nitrogen (C/N) ratio and moisture content (MC) on the survival of ESBL-producing E. coli during laboratory-scale composting of chicken manure.	Nitrogen	72-80	EsbL	Escherichia coli	138-142
32108198-3	2020	The reaction was triggered by addition of a SCF3 radical to a carbon-carbon double bond and involved the formation of a C(sp3)-SCF3 bond, a C(sp2)-C bond, and a C(sp2)-N bond.	Nitrogen	168-169	Sp2 transcription factor	Homo sapiens	161-166
31926412-2	2020	Its monomer unit, N-acetyl-D-glucosamine (NAG), contains precious atomic nitrogen and represents a potential feedstock for the manufacture of regenerative organic nitrogen chemicals.	Nitrogen	73-81	N-acetyl-alpha-glucosaminidase	Homo sapiens	42-45
31926412-2	2020	Its monomer unit, N-acetyl-D-glucosamine (NAG), contains precious atomic nitrogen and represents a potential feedstock for the manufacture of regenerative organic nitrogen chemicals.	Nitrogen	163-171	N-acetyl-alpha-glucosaminidase	Homo sapiens	42-45
32017423-1	2020	In this paper, we have used two N,O-ketiminato ligands ( L1 and L2 ) with biphenyl and terphenyl substituent on the nitrogen atom.	Nitrogen	116-124	L1 cell adhesion molecule	Homo sapiens	57-66
31923504-4	2020	The best aggregation inhibitor (a phenyl derivative of N-nornoscapine) also demonstrated the highest ability to stabilize native insulin against thermal denaturation.	Nitrogen	55-69	insulin	Homo sapiens	129-136
31884371-7	2020	N-CQDs/AuNCs probe present a good sensitivity and selectivity for carbendazim detection, with two linear response ranges (1-100 muM, 150-1000 muM), low detection limit of 0.83 muM and 37.25 muM.	Nitrogen	0-1	latexin	Homo sapiens	128-131
31884371-7	2020	N-CQDs/AuNCs probe present a good sensitivity and selectivity for carbendazim detection, with two linear response ranges (1-100 muM, 150-1000 muM), low detection limit of 0.83 muM and 37.25 muM.	Nitrogen	0-1	latexin	Homo sapiens	142-145
31884371-7	2020	N-CQDs/AuNCs probe present a good sensitivity and selectivity for carbendazim detection, with two linear response ranges (1-100 muM, 150-1000 muM), low detection limit of 0.83 muM and 37.25 muM.	Nitrogen	0-1	latexin	Homo sapiens	142-145
31884371-7	2020	N-CQDs/AuNCs probe present a good sensitivity and selectivity for carbendazim detection, with two linear response ranges (1-100 muM, 150-1000 muM), low detection limit of 0.83 muM and 37.25 muM.	Nitrogen	0-1	latexin	Homo sapiens	142-145
32039437-5	2020	The UBE3C HECT domain forms an open, L-shaped, bilobed conformation, having a large N-lobe and a small C-lobe.	Nitrogen	84-85	ubiquitin protein ligase E3C	Homo sapiens	4-9
32039437-6	2020	We show that the N-terminal region (aa 693-743) preceding the UBE3C HECT domain as well as a loop region (aa 758-762) in the N-lobe of the HECT domain affect the stability and activity of UBE3C HECT domain.	Nitrogen	17-18	ubiquitin protein ligase E3C	Homo sapiens	62-67
32039437-6	2020	We show that the N-terminal region (aa 693-743) preceding the UBE3C HECT domain as well as a loop region (aa 758-762) in the N-lobe of the HECT domain affect the stability and activity of UBE3C HECT domain.	Nitrogen	17-18	ubiquitin protein ligase E3C	Homo sapiens	188-193
32039437-6	2020	We show that the N-terminal region (aa 693-743) preceding the UBE3C HECT domain as well as a loop region (aa 758-762) in the N-lobe of the HECT domain affect the stability and activity of UBE3C HECT domain.	Nitrogen	125-126	ubiquitin protein ligase E3C	Homo sapiens	62-67
32039437-6	2020	We show that the N-terminal region (aa 693-743) preceding the UBE3C HECT domain as well as a loop region (aa 758-762) in the N-lobe of the HECT domain affect the stability and activity of UBE3C HECT domain.	Nitrogen	125-126	ubiquitin protein ligase E3C	Homo sapiens	188-193
32087368-5	2020	Furthermore, we find that both darkness and nitrogen depletion can induce the degradation of HY5 via 26S proteasome and the concomitant disassociation of HDA9 from ATG5 and ATG8e loci to relieve their repression, thereby activating autophagy.	Nitrogen	44-52	autophagy related 5	Homo sapiens	164-168
32226879-1	2020	In yeast, the formation of Ure2 fibrils underlies the prion state [URE3], in which the yeast loses the ability to distinguish good nitrogen sources from bad ones.	Nitrogen	131-139	glutathione peroxidase	Saccharomyces cerevisiae S288C	27-31
32211003-3	2020	Nitrate (NO3 -) is often the primary nitrogen source, but it also serves as a signaling molecule to the plant.	Nitrogen	37-45	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
32049056-4	2020	We covalently labeled each lobe of CaM (N and C) with fluorescent probes and used intramolecular TR-FRET to assess interlobe distances when CaM is bound to RyR1 in SR membranes, purified RyR1, or a peptide corresponding to the CaM-binding domain of RyR (RyRp).	Nitrogen	40-41	calmodulin 1	Homo sapiens	35-38
32008081-0	2020	Development of a liquid-nitrogen-induced homogeneous liquid-liquid microextraction of Co(II) and Ni(II) from water and fruit juice samples followed by atomic absorption spectrometry detection.	Nitrogen	24-32	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	86-103
31953035-7	2020	Galanin treatment increased cholangiocyte proliferation and fibrogenesis in both FVB/N and Mdr2KO mice.	Nitrogen	85-86	galanin and GMAP prepropeptide	Mus musculus	0-7
32008081-1	2020	In this study, a simple and rapid sample preparation method named liquid-nitrogen-induced homogeneous liquid-liquid microextraction has been developed for the extraction and pre-concentration of Co(II) and Ni(II) ions before their analysis by flame atomic absorption spectrometry.	Nitrogen	73-81	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	195-201
30851431-2	2020	These drugs and agrochemicals contain an imidazole, triazole or tetrazole substituent, with one of the nitrogens in the azole ring coordinating as the sixth axial ligand to the LDM heme iron.	Nitrogen	103-112	cytochrome P450 family 51 subfamily A member 1	Homo sapiens	177-180
32104255-7	2020	miR-27a expression level was found to be associated with blood urea nitrogen, partial pressure of carbon dioxide, arterial blood lactic acid, and the acute physiology and chronic health evaluation II score (APACHE II; P&lt;0.05).	Nitrogen	68-76	microRNA 27a	Homo sapiens	0-7
31760285-8	2020	The proposed method is helpful to understand the origins of NO3- and may be suitable to develop measures for the reducing of nitrogen loadings in the peri-urban watershed.	Nitrogen	125-133	NBL1, DAN family BMP antagonist	Homo sapiens	60-63
31744758-2	2020	The formation and structure of beta-CD-PNIPAM@MSN-Fc composite nanoparticles was confirmed by FTIR, TGA, TEM and N2 adsorption-desorption isotherms.	Nitrogen	113-115	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	31-38
31891836-6	2020	When the Cd and N-CDs concentration are respective 20 mg kg-1 and 4 mg kg-1, the enzyme activities of the catalase and peroxidase increased to 2.73-fold and 1.45-fold, respectively.	Nitrogen	16-17	peroxidase	Arabidopsis thaliana	119-129
31775099-4	2020	At 200 mg L-1 phenol, 99.8% phenol, 97.5% COD and 89.8% nitrogen could be together removed.	Nitrogen	56-64	immunoglobulin kappa variable 1-16	Homo sapiens	10-13
32044349-9	2020	Serum Metrnl levels were negatively correlated with VFA, total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and albumin (ALB), but positively correlated with age, height, blood urea nitrogen (BUN), creatinine (Cr) and uric acid (UA) (all P < 0.05).	Nitrogen	218-226	albumin	Homo sapiens	157-160
31874363-1	2020	Four Co(III) ternary complexes with the composition of [(Co(4 N))2(quin)](ClO4)4 or [(Co(4 N))2(quinS)](ClO4)3, where 4 N = tris(2-aminoethyl)amine (tren) or tris(2-pyridylmethyl)amine (tpa), quinH2 = quinizarin (1,4-dihydroxy-9,10-anthraquinone), quinSH3 = quinizarin-2-sulfonic acid (1,4-dihydroxy-9,10-anthraquinone-2-sulfonic acid), were synthesized, characterized and their human serum albumin (HSA) binding capabilities were also tested.	Nitrogen	62-63	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	5-12
31858211-10	2020	Dietary supplementation with a high n-6/n-3 ratio downregulated the protein expression of Cx45 and Panx1 in diabetic rats (p < 0.05-p < 0.01), while Cx43 immunoexpression was increased in diabetic rats fed with high and low n-6/n-3 ratios (p < 0.01-p < 0.001).	Nitrogen	16-17	gap junction protein, alpha 1	Rattus norvegicus	149-153
31858211-10	2020	Dietary supplementation with a high n-6/n-3 ratio downregulated the protein expression of Cx45 and Panx1 in diabetic rats (p < 0.05-p < 0.01), while Cx43 immunoexpression was increased in diabetic rats fed with high and low n-6/n-3 ratios (p < 0.01-p < 0.001).	Nitrogen	22-23	gap junction protein, alpha 1	Rattus norvegicus	149-153
31693237-5	2020	In previous cell-based assays, we found that certain N-terminally truncated PTH and PTHrP antagonist peptides function as inverse agonists and thus can reduce the high rates of basal cAMP signaling exhibited by the mutant PTHR1s of JMC in vitro.	Nitrogen	53-54	parathyroid hormone-like peptide	Mus musculus	84-89
31722428-0	2020	Role of the N-terminus in human 4-hydroxyphenylpyruvate dioxygenase activity.	Nitrogen	12-13	4-hydroxyphenylpyruvate dioxygenase	Homo sapiens	32-67
31874363-5	2020	These potentials are in the range of typical (O,O) chelated Co(III) ternary complexes bearing 4 N donor ligands and follow the order being more positive for the tpa containing complexes.	Nitrogen	96-97	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	60-67
32060587-1	2020	p38 mitogen-activated protein kinases (P38alpha and beta) and c-Jun N-terminal kinases (JNK1, 2, and 3) are key mediators of the cellular stress response.	Nitrogen	68-69	mitogen-activated protein kinase 8	Homo sapiens	88-102
31705961-10	2020	Vit.D significantly increased aromatase and 3beta-hydroxysteroid dehydrogenase activity in N-GCs and PCO-GCs.	Nitrogen	91-92	vitrin	Homo sapiens	0-3
31809770-2	2020	The incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) and the related hormone glucagon-like peptide-2 (GLP-2) are all rapidly N-terminally truncated with severe loss of intrinsic activity.	Nitrogen	182-183	gastric inhibitory polypeptide	Homo sapiens	23-67
31809770-2	2020	The incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) and the related hormone glucagon-like peptide-2 (GLP-2) are all rapidly N-terminally truncated with severe loss of intrinsic activity.	Nitrogen	182-183	glucagon	Homo sapiens	78-101
31809770-2	2020	The incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) and the related hormone glucagon-like peptide-2 (GLP-2) are all rapidly N-terminally truncated with severe loss of intrinsic activity.	Nitrogen	182-183	glucagon	Homo sapiens	159-164
31809770-6	2020	Here, we review the action of these four and multiple other N- and C-terminally truncated forms of GIP with an emphasis on molecular pharmacology, i.e. ligand binding, subsequent receptor activation and desensitization.	Nitrogen	60-61	gastric inhibitory polypeptide	Homo sapiens	99-102
31809770-7	2020	Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution.	Nitrogen	35-36	gastric inhibitory polypeptide	Homo sapiens	86-89
31705961-13	2020	Basal ROS in PCO-GCs was markedly greater than that of N-GCs, which was attenuated by vit.D treatment.	Nitrogen	55-56	vitrin	Homo sapiens	86-89
31809770-7	2020	Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution.	Nitrogen	35-36	gastric inhibitory polypeptide	Homo sapiens	236-239
31809770-7	2020	Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution.	Nitrogen	35-36	glucagon	Homo sapiens	269-274
31705961-15	2020	We conclude that vit.D improved N-GCs and PCO-GCs functions through affecting steroidogenesis and enzymatic antioxidant defense.	Nitrogen	32-33	vitrin	Homo sapiens	17-20
31809770-7	2020	Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution.	Nitrogen	35-36	gastric inhibitory polypeptide receptor	Homo sapiens	339-343
31809770-7	2020	Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution.	Nitrogen	90-91	gastric inhibitory polypeptide	Homo sapiens	86-89
31705961-16	2020	Under vit.D treatment, PCO-GCs could act more similar to N-GCs.	Nitrogen	57-58	vitrin	Homo sapiens	6-9
31925419-2	2020	We previously determined the structure of a short motif in the disordered XPA N-terminus bound to the RPA32C domain.	Nitrogen	78-79	XPA, DNA damage recognition and repair factor	Homo sapiens	74-77
31953325-0	2020	The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation.	Nitrogen	15-16	histone deacetylase 6	Homo sapiens	29-34
31953325-3	2020	Here, using recombinant protein expression, site-directed mutagenesis, fluorimetric and biochemical assays, microscale thermophoresis, and total internal reflection fluorescence microscopy, we identified the N-terminal, disordered region of HDAC6 as a microtubule-binding domain (MBD) and functionally characterized it to the single-molecule level.	Nitrogen	208-209	histone deacetylase 6	Homo sapiens	241-246
31950363-6	2020	Compared to the control group, monotherapy and combination therapy with PTH and/or Scl-Ab promoted the formation of new bone, enhanced maximum femoral loading and increased the levels of procollagen type I N-terminal propeptide (PINP) and osteocalcin.	Nitrogen	206-207	parathyroid hormone	Rattus norvegicus	72-75
32073082-4	2020	Theoretical calculations indicate that coupling Mo2C, N and CANs into a hybrid results in producing wrinkles on carbon nanolayers, which changes the direction of sp2 hybrid orbitals to push the Gibbs free energy toward zero.	Nitrogen	54-55	Sp2 transcription factor	Homo sapiens	162-165
31858971-0	2020	Identification of the minimal N-glycosylation on integrin alpha5beta1 required for its inhibitory effect on EGFR signaling and cell proliferation.	Nitrogen	30-31	epidermal growth factor receptor	Bos taurus	108-112
31858971-8	2020	Taken together, these data indicate that alpha5S3-5+10-14beta1S4-6+1-3 mutant represents the minimal N-glycosylation required for its regulation on EGFR signaling and cell proliferation, providing a plausible mechanism for the crosstalk between with alpha5beta1 and EGFR.	Nitrogen	101-102	epidermal growth factor receptor	Bos taurus	148-152
31858971-8	2020	Taken together, these data indicate that alpha5S3-5+10-14beta1S4-6+1-3 mutant represents the minimal N-glycosylation required for its regulation on EGFR signaling and cell proliferation, providing a plausible mechanism for the crosstalk between with alpha5beta1 and EGFR.	Nitrogen	101-102	epidermal growth factor receptor	Bos taurus	266-270
31858971-2	2020	Our group previously reported that the N-glycosylation of the Calf-1,2 domain on alpha5 subunit (S3-5,10-14) was important for its inhibitory effect on EGFR signaling through regulating alpha5-EGFR complex formation.	Nitrogen	39-40	epidermal growth factor receptor	Bos taurus	152-156
31858971-2	2020	Our group previously reported that the N-glycosylation of the Calf-1,2 domain on alpha5 subunit (S3-5,10-14) was important for its inhibitory effect on EGFR signaling through regulating alpha5-EGFR complex formation.	Nitrogen	39-40	epidermal growth factor receptor	Bos taurus	193-197
31858971-3	2020	In this follow-up study, we provide evidence that the N-glycosylation on integrin beta1 subunit suppress cell growth by promoting its association with EGFR under fibronectin (FN)-coated conditions.	Nitrogen	54-55	epidermal growth factor receptor	Bos taurus	151-155
31858971-6	2020	Mechanistically, the N-glycosylation mutant of beta1 (S4-6+1-3) inhibited the EGFR response upon EGF stimulation via facilitating the alpha5beta1-EGFR complex formation.	Nitrogen	21-22	epidermal growth factor receptor	Bos taurus	78-82
32175496-9	2020	In contrast, HI-6 and 2-PAM showed higher affinities with more negative binding energy values and larger contribution of the amino acid Asp74, demonstrating the importance of the quaternary nitrogen to the affinity and interaction of oximes with AChE-GB and AChE-VX conjugates.	Nitrogen	190-198	acetylcholinesterase (Cartwright blood group)	Homo sapiens	246-250
31858971-6	2020	Mechanistically, the N-glycosylation mutant of beta1 (S4-6+1-3) inhibited the EGFR response upon EGF stimulation via facilitating the alpha5beta1-EGFR complex formation.	Nitrogen	21-22	epidermal growth factor receptor	Bos taurus	146-150
31858971-7	2020	Moreover, we identified the N-glycosylation of sites 10-14 on alpha5 and 1-3 on beta1 were most important for EGFR signaling.	Nitrogen	28-29	epidermal growth factor receptor	Bos taurus	110-114
32023068-1	2020	The first feedback inhibition, similar to enzyme catalysis, in the Co(III)salen-catalyzed asymmetric ring-opening reaction of N-free spiro-epoxyoxyindole has been discovered, which leads dynamic kinetic to kinetic resolution.	Nitrogen	126-127	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	67-73
31932304-6	2020	The results of these analyses indicated that Opi3 (as well as PEMT) has an N-out C-in topology and contains four transmembrane domains, with the fourth forming a re-entrant loop.	Nitrogen	75-76	phosphatidylethanolamine N-methyltransferase	Homo sapiens	62-66
31937588-4	2020	We found that FIH1 modifies Asn35 within the uncharacterized N-terminal ubiquitin-associated (UBA)-like domain of Cezanne (UBACez), which lacks conserved UBA domain properties.	Nitrogen	61-62	OTU deubiquitinase 7B	Homo sapiens	114-121
31899794-6	2020	We show that BMP6 binds the N-terminal domain of ERFE, and a polypeptide derived from the N-terminus of ERFE was sufficient to cause hepcidin suppression in Huh7 hepatoma cells and in wildtype mice.	Nitrogen	28-29	bone morphogenetic protein 6	Homo sapiens	13-17
31899794-7	2020	Anti-ERFE antibodies targeting the N-terminal domain prevented hepcidin suppression in ERFE-treated Huh7 cells and in EPO-treated mice.	Nitrogen	35-36	erythropoietin	Homo sapiens	118-121
31877357-0	2020	Caveolin-1 dictates ferroptosis in the execution of acute immune-mediated hepatic damage by attenuating nitrogen stress.	Nitrogen	104-112	caveolin 1	Homo sapiens	0-10
31877357-5	2020	Additionally, Cav-1 deficiency aggravated ConA-induced hepatocellular death and ferroptosis associated with excessive nitrogen stress response.	Nitrogen	118-126	caveolin 1	Homo sapiens	14-19
32077676-2	2020	Yin Yang 1 is composed of an N-terminal intrinsically disordered fragment and a C-terminal domain responsible for binding to DNA, composed of four zinc fingers.	Nitrogen	29-30	YY1 transcription factor	Homo sapiens	0-10
31899794-9	2020	In summary, we demonstrate that ERFE binds BMP6 directly and with high affinity, and that antibodies targeting the N-terminal domain of ERFE that prevent ERFE-BMP6 interactions constitute a potential therapeutic tool for iron-loading anemias.	Nitrogen	115-116	erythroferrone	Mus musculus	136-140
31899794-9	2020	In summary, we demonstrate that ERFE binds BMP6 directly and with high affinity, and that antibodies targeting the N-terminal domain of ERFE that prevent ERFE-BMP6 interactions constitute a potential therapeutic tool for iron-loading anemias.	Nitrogen	115-116	erythroferrone	Mus musculus	136-140
32019887-8	2020	High-affinity binding of InsP8 to the XPR1 N-terminus (K d = 180 nM) was demonstrated by isothermal titration calorimetry.	Nitrogen	43-44	xenotropic and polytropic retrovirus receptor 1	Homo sapiens	38-42
32140162-10	2020	Temperature, MA/CA, and 1-MCP alter fruit physiology and biochemistry, resulting in compositional changes in carbon- and nitrogen-related metabolisms and compounds.	Nitrogen	121-129	CD46 molecule	Homo sapiens	26-29
32110741-2	2020	The increase of N2 flow rate facilitated the increase of C-C sp2/sp3 ratio (1.09-2.66), the growth of particle size (0.78-1.58 nm) and the improvement of surface roughness.	Nitrogen	16-18	von Willebrand factor A domain containing 2	Homo sapiens	57-64
32110741-2	2020	The increase of N2 flow rate facilitated the increase of C-C sp2/sp3 ratio (1.09-2.66), the growth of particle size (0.78-1.58 nm) and the improvement of surface roughness.	Nitrogen	16-18	Sp3 transcription factor	Homo sapiens	65-68
31919512-7	2020	A loop in BCDIN3D is shorter, as compared to the corresponding region that forms an alpha-helix to recognize the 5"-end of RNA in MePCE, and the G-1:A73 mispair in tRNAHis allows the N-terminal alpha-helix of BCDIN3D to wedge the G-1:A73 mispair of tRNAHis.	Nitrogen	14-15	methylphosphate capping enzyme	Homo sapiens	130-135
31919512-7	2020	A loop in BCDIN3D is shorter, as compared to the corresponding region that forms an alpha-helix to recognize the 5"-end of RNA in MePCE, and the G-1:A73 mispair in tRNAHis allows the N-terminal alpha-helix of BCDIN3D to wedge the G-1:A73 mispair of tRNAHis.	Nitrogen	14-15	BCDIN3 domain containing RNA methyltransferase	Homo sapiens	209-216
31896222-5	2020	It was found that the nitrogen isotopic values of nitrate in PM2.5 (hereafter as delta15N-NO3-) ranged widely from -3.1% to + 11.4%, with a mean value of 3.5 +- 3.7%.	Nitrogen	22-30	NBL1, DAN family BMP antagonist	Homo sapiens	90-93
31896222-7	2020	This implied the preferential formation of 15N-enriched NO3- into a fine-particle aerosol.	Nitrogen	43-46	NBL1, DAN family BMP antagonist	Homo sapiens	56-59
31970984-3	2020	Grb2 consists of an SH2 domain flanked by N- and C-terminal SH3 domains (nSH3/cSH3).	Nitrogen	42-43	growth factor receptor bound protein 2	Homo sapiens	0-4
31994866-3	2020	Specifically, the carboxyl-group-free Tb peptides are self-assembled onto gold electrode surface via the N-terminal cysteine residue and are used for the specific recognition of thrombin molecules.	Nitrogen	105-106	coagulation factor II, thrombin	Homo sapiens	178-186
32070329-14	2020	Moreover, IPF-HLF derived supernatants induced both direct and indirect STAT3 activation that resulted in Smad3 phosphorylation and elevated Gremlin levels in N-HLFs.	Nitrogen	159-160	signal transducer and activator of transcription 3	Homo sapiens	72-77
32070329-14	2020	Moreover, IPF-HLF derived supernatants induced both direct and indirect STAT3 activation that resulted in Smad3 phosphorylation and elevated Gremlin levels in N-HLFs.	Nitrogen	159-160	gremlin 1, DAN family BMP antagonist	Homo sapiens	141-148
32070329-16	2020	CONCLUSIONS: IPF-HLF paracrine signaling leads to IL-6R overexpression, which in turn, affects N-HLF survival.	Nitrogen	2-3	interleukin 6 receptor	Homo sapiens	50-55
32045013-4	2022	N-myristoyltransferase (NMT) is an essential enzyme to parasites and has been validated as a chemically tractable target for the discovery of new drug candidates against malaria.	Nitrogen	0-1	N-myristoyltransferase 1	Homo sapiens	24-27
32079099-4	2020	In addition, eqTHN N-glycosylation mutants colocalize obviously with ER, CD63, LAMP1 and endosomes, while WT eqTHN do not.	Nitrogen	17-18	lysosomal associated membrane protein 1	Equus caballus	79-84
31792058-7	2020	Remarkably, a chimeric BET protein comprising the N-terminal half of the structurally similar short BRD4 isoform (BRD4S) and the C-terminal half of BRD2 functioned similarly to intact BRD2.	Nitrogen	50-51	bromodomain containing 4	Homo sapiens	100-104
31785816-4	2020	AGAP1 binds to C-terminus of FilGAP whereas FilGAP binds to N-terminus of AGAP1 containing GLD domain.	Nitrogen	60-61	Rho GTPase activating protein 24	Homo sapiens	44-50
32065312-7	2020	Up-regulation of expression of ZmAMT1.3, ZmNRT2.1, and ZmAAP2 in the root and that of ZmAMT1.1, ZmAMT1.3, and ZmLHT1 in the shoot preconditioned N over-accumulation in the shoot and facilitated shoot growth, presumably via enhancing N translocation to the shoot, when Gln was supplied.	Nitrogen	145-146	LHT1	Zea mays	110-116
31740260-1	2020	We develop a low-background electrochemical biosensor for one-step detection of uracil DNA glycosylase (UDG) based on the host-guest interaction and iron-embedded nitrogen-rich carbon nanotube (Fe-N-C) that mimics enzyme-mediated electrocatalysis to achieve signal amplification.	Nitrogen	163-171	uracil DNA glycosylase	Homo sapiens	80-102
31740260-1	2020	We develop a low-background electrochemical biosensor for one-step detection of uracil DNA glycosylase (UDG) based on the host-guest interaction and iron-embedded nitrogen-rich carbon nanotube (Fe-N-C) that mimics enzyme-mediated electrocatalysis to achieve signal amplification.	Nitrogen	163-171	uracil DNA glycosylase	Homo sapiens	104-107
32069989-5	2020	The activation of extrinsic apoptosis evidenced with the reduction of c-FLIP and caspase-8, as well as the modulation of intrinsic apoptosis signaling proteins including Bax and Mcl-1 were observed via Western blot analysis in lung cancer cells cultured with colicin N (10-15 microM) for 12 h. Moreover, 5-15 microM of colicin N down-regulated the expression of activated Akt (p-Akt) and its upstream survival molecules, integrin beta1 and alphaV in human lung cancer cells.	Nitrogen	259-268	BCL2 associated X, apoptosis regulator	Homo sapiens	170-173
32069989-5	2020	The activation of extrinsic apoptosis evidenced with the reduction of c-FLIP and caspase-8, as well as the modulation of intrinsic apoptosis signaling proteins including Bax and Mcl-1 were observed via Western blot analysis in lung cancer cells cultured with colicin N (10-15 microM) for 12 h. Moreover, 5-15 microM of colicin N down-regulated the expression of activated Akt (p-Akt) and its upstream survival molecules, integrin beta1 and alphaV in human lung cancer cells.	Nitrogen	319-328	BCL2 associated X, apoptosis regulator	Homo sapiens	170-173
32049977-6	2020	We, here, revisit the question for human matriptase through the use of a fusion protein containing a green fluorescent protein linked to the matriptase N-terminal fragment ending at Gly-149.	Nitrogen	152-153	ST14 transmembrane serine protease matriptase	Rattus norvegicus	41-51
32049977-6	2020	We, here, revisit the question for human matriptase through the use of a fusion protein containing a green fluorescent protein linked to the matriptase N-terminal fragment ending at Gly-149.	Nitrogen	152-153	ST14 transmembrane serine protease matriptase	Rattus norvegicus	141-151
31965130-7	2020	The prolonged reaction zone uncovers the slowed decomposition kinetics of CL-20/HMX and CL-20/TNT, which is associated with the altered kinetics of CL-20 decomposition specifically by N-NO2 bond scission and CL-20 skeleton decay.	Nitrogen	184-189	epithelial membrane protein 1	Homo sapiens	74-79
32042062-1	2020	The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity.	Nitrogen	10-11	N-alpha-acetyltransferase 15, NatA auxiliary subunit	Homo sapiens	88-93
32046099-3	2020	We briefly discuss new findings in the extracellular signaling-regulated kinase (ERK) pathway, but mainly focus on the mechanisms how stress activated MAPK pathways, such as p38 MAPK and the Jun N-terminal kinases (JNK), impact the response of cancer cells to chemotherapies and targeted therapies.	Nitrogen	195-196	mitogen-activated protein kinase 1	Homo sapiens	39-79
31965130-7	2020	The prolonged reaction zone uncovers the slowed decomposition kinetics of CL-20/HMX and CL-20/TNT, which is associated with the altered kinetics of CL-20 decomposition specifically by N-NO2 bond scission and CL-20 skeleton decay.	Nitrogen	184-189	epithelial membrane protein 1	Homo sapiens	88-93
31965130-7	2020	The prolonged reaction zone uncovers the slowed decomposition kinetics of CL-20/HMX and CL-20/TNT, which is associated with the altered kinetics of CL-20 decomposition specifically by N-NO2 bond scission and CL-20 skeleton decay.	Nitrogen	184-189	chromosome 16 open reading frame 82	Homo sapiens	94-97
31965130-7	2020	The prolonged reaction zone uncovers the slowed decomposition kinetics of CL-20/HMX and CL-20/TNT, which is associated with the altered kinetics of CL-20 decomposition specifically by N-NO2 bond scission and CL-20 skeleton decay.	Nitrogen	184-189	epithelial membrane protein 1	Homo sapiens	88-93
31965130-7	2020	The prolonged reaction zone uncovers the slowed decomposition kinetics of CL-20/HMX and CL-20/TNT, which is associated with the altered kinetics of CL-20 decomposition specifically by N-NO2 bond scission and CL-20 skeleton decay.	Nitrogen	184-189	epithelial membrane protein 1	Homo sapiens	88-93
31968931-5	2020	More than one unit variation in logK indicates an intrinsic dissimilarity in metal affinity of the C- and N-lobes of Tf, which agrees well with earlier reported ensemble spectroscopy results.	Nitrogen	106-107	transferrin	Homo sapiens	117-119
31784087-5	2020	Insertion of a missense mutation (E551K) in the Drosophila kinesin-2alpha stalk fragment, which was shown to reduce the structural dynamics of the stalk heterodimer earlier, also reduced the distances at both the N- and C-terminal ends of the stalk heterodimer independent of DmKAP.	Nitrogen	213-214	Kinesin associated protein 3	Drosophila melanogaster	276-281
31784087-6	2020	The zipping effect, particularly at the N-terminal end of the mutant stalk heterodimer, is further enhanced in the presence of DmKAP.	Nitrogen	40-41	Kinesin associated protein 3	Drosophila melanogaster	127-132
31872752-3	2020	Second, the NO3- could be in situ reduced easily to the active nitrogen species by means of the pore confinement effect, which could be served as a new coreactant for nanocrystal-based ECL amplification with the excellent stability and good biocompatibility.	Nitrogen	63-71	NBL1, DAN family BMP antagonist	Homo sapiens	12-15
31895557-1	2020	Gid4, a subunit of the ubiquitin ligase GID, is the recognition component of the Pro/N-degron pathway.	Nitrogen	85-86	glucose-induced degradation complex subunit VID24	Saccharomyces cerevisiae S288C	0-4
31895557-2	2020	Gid4 targets proteins in particular through their N-terminal (Nt) proline (Pro) residue.	Nitrogen	50-51	glucose-induced degradation complex subunit VID24	Saccharomyces cerevisiae S288C	0-4
31843715-9	2020	SAP-drug (anti-TNF-alpha/HGF in SAP hydrogel) treatment reduced the level of serum creatinine (Scr), blood urea nitrogen (BUN), tubular apoptosis, renal inflammatory factors, and macrophage infiltration compared to Free-drug (anti-TNF-alpha/HGF in solution) or SAP alone.	Nitrogen	112-120	tumor necrosis factor	Mus musculus	15-24
32033048-2	2020	Smurf1 contains an N-terminal protein kinase C conserved 2 (C2) domain that targets cell membranes and is required for interactions with membrane-localized substrates such as RhoA.	Nitrogen	19-20	SMAD specific E3 ubiquitin protein ligase 1	Homo sapiens	0-6
32033048-2	2020	Smurf1 contains an N-terminal protein kinase C conserved 2 (C2) domain that targets cell membranes and is required for interactions with membrane-localized substrates such as RhoA.	Nitrogen	19-20	ras homolog family member A	Homo sapiens	175-179
32019925-2	2020	Here we identify a novel and critical function of IKK2 and its co-factor NEMO in the activation of oncogenic c-Jun N-terminal kinase (JNK) signaling, induced by the latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV).	Nitrogen	73-74	mitogen-activated protein kinase 8	Homo sapiens	134-137
32019936-2	2020	The eukaryotic replicative CMG (Cdc45, Mcm2-7, GINS) helicase contains a Mcm2-7 motor ring, with the N-tier ring in front and the C-tier motor ring behind.	Nitrogen	49-50	cell division cycle 45	Homo sapiens	32-37
31555812-6	2020	The various N-terminal tags, GFP-related Ruby and FLAG, rendered the export CRM1-dependent and especially FLAG-tag caused nuclear accumulation of STAT3, indicating the presence of conformational changes in inactivation.	Nitrogen	12-13	signal transducer and activator of transcription 3	Homo sapiens	146-151
31843715-9	2020	SAP-drug (anti-TNF-alpha/HGF in SAP hydrogel) treatment reduced the level of serum creatinine (Scr), blood urea nitrogen (BUN), tubular apoptosis, renal inflammatory factors, and macrophage infiltration compared to Free-drug (anti-TNF-alpha/HGF in solution) or SAP alone.	Nitrogen	112-120	SH2 domain containing 1A	Mus musculus	0-3
31843715-9	2020	SAP-drug (anti-TNF-alpha/HGF in SAP hydrogel) treatment reduced the level of serum creatinine (Scr), blood urea nitrogen (BUN), tubular apoptosis, renal inflammatory factors, and macrophage infiltration compared to Free-drug (anti-TNF-alpha/HGF in solution) or SAP alone.	Nitrogen	112-120	SH2 domain containing 1A	Mus musculus	32-35
31705849-3	2020	This modulation depends on the behavior of the N-terminal domain (NTD), which can be adsorbed onto the OMM (nonactive CPT 1A) or interacting with the C-terminal domain (active CPT 1A).	Nitrogen	47-48	carnitine palmitoyltransferase 1A	Homo sapiens	118-124
31705849-3	2020	This modulation depends on the behavior of the N-terminal domain (NTD), which can be adsorbed onto the OMM (nonactive CPT 1A) or interacting with the C-terminal domain (active CPT 1A).	Nitrogen	47-48	carnitine palmitoyltransferase 1A	Homo sapiens	176-182
31924504-4	2020	This paper describes the development of 6-aryloxy-N-hydroxy-2-quinolineacrylamides as potential HDAC6 inhibitors.	Nitrogen	40-82	histone deacetylase 6	Homo sapiens	96-101
31744379-5	2020	In parallel, ER-residing molecular chaperones, such as HSPA5/GRP78/BiP, are relocated to the cytosol and conjugated with the amino acid L-arginine (Arg) at the N-termini by ATE1 (arginyltransferase 1).	Nitrogen	160-161	heat shock protein family A (Hsp70) member 5	Homo sapiens	55-60
31744379-5	2020	In parallel, ER-residing molecular chaperones, such as HSPA5/GRP78/BiP, are relocated to the cytosol and conjugated with the amino acid L-arginine (Arg) at the N-termini by ATE1 (arginyltransferase 1).	Nitrogen	160-161	heat shock protein family A (Hsp70) member 5	Homo sapiens	61-66
31744379-5	2020	In parallel, ER-residing molecular chaperones, such as HSPA5/GRP78/BiP, are relocated to the cytosol and conjugated with the amino acid L-arginine (Arg) at the N-termini by ATE1 (arginyltransferase 1).	Nitrogen	160-161	heat shock protein family A (Hsp70) member 5	Homo sapiens	67-70
31662101-7	2020	The NMR experiments for 15N-labeled HyC1 scFv indicated that the flexibility of HyC1 scFv decreased upon the binding to HEL.	Nitrogen	24-27	immunglobulin heavy chain variable region	Homo sapiens	41-45
31662101-7	2020	The NMR experiments for 15N-labeled HyC1 scFv indicated that the flexibility of HyC1 scFv decreased upon the binding to HEL.	Nitrogen	24-27	immunglobulin heavy chain variable region	Homo sapiens	85-89
31874060-2	2020	Inhibition of PDE10A represents a molecular target in the treatment of conditions that would benefit from the increase of the level of cAMP and/or cGMP such as neurological and psychiatric disorders, cancer, and diabetes.Areas covered: The present article reviews the patent literature on PDE10A inhibitors (PDE10AIs) from 2014 to present and PDE10AI chemotypes from different chemical classes: heteroaryl- and aryl-nitrogen-heterocyclic compounds, unsaturated nitrogen-heterocyclic compounds with specific substituents such as pyrazolopyrimidine, aryloxymethyl cyclopropane, pyridizinone, imidazopyridine, triazoles and imidazo[2,1-a]isoidole.	Nitrogen	411-437	phosphodiesterase 10A	Homo sapiens	14-20
31848955-8	2020	Compared with control, N addition increased mineralization of exchangeable SON to promote nitrification regardless of soils, but weakened the immobilization of NO3-.	Nitrogen	23-24	NBL1, DAN family BMP antagonist	Homo sapiens	160-163
31855846-0	2020	Macromolecular crowding induces compaction and DNA binding in the disordered N-terminal domain of hUNG2.	Nitrogen	48-49	uracil DNA glycosylase	Homo sapiens	98-103
31855846-2	2020	We recently reported that the partially structured N-terminal domain (NTD) of human uracil DNA glycosylase 2 (hUNG2), functions to enhance DNA translocation in crowded environments and also targets the enzyme to single-stranded/double-stranded DNA junctions.	Nitrogen	51-52	uracil DNA glycosylase	Homo sapiens	110-115
31625555-5	2020	Importantly, biomarkers, including cardiac troponins and N-terminal pro-brain natriuretic peptide, are associated with thrombin generation and fibrin-related markers in AF patients.	Nitrogen	57-58	coagulation factor II, thrombin	Homo sapiens	119-127
31874060-2	2020	Inhibition of PDE10A represents a molecular target in the treatment of conditions that would benefit from the increase of the level of cAMP and/or cGMP such as neurological and psychiatric disorders, cancer, and diabetes.Areas covered: The present article reviews the patent literature on PDE10A inhibitors (PDE10AIs) from 2014 to present and PDE10AI chemotypes from different chemical classes: heteroaryl- and aryl-nitrogen-heterocyclic compounds, unsaturated nitrogen-heterocyclic compounds with specific substituents such as pyrazolopyrimidine, aryloxymethyl cyclopropane, pyridizinone, imidazopyridine, triazoles and imidazo[2,1-a]isoidole.	Nitrogen	411-437	phosphodiesterase 10A	Homo sapiens	289-295
31874060-2	2020	Inhibition of PDE10A represents a molecular target in the treatment of conditions that would benefit from the increase of the level of cAMP and/or cGMP such as neurological and psychiatric disorders, cancer, and diabetes.Areas covered: The present article reviews the patent literature on PDE10A inhibitors (PDE10AIs) from 2014 to present and PDE10AI chemotypes from different chemical classes: heteroaryl- and aryl-nitrogen-heterocyclic compounds, unsaturated nitrogen-heterocyclic compounds with specific substituents such as pyrazolopyrimidine, aryloxymethyl cyclopropane, pyridizinone, imidazopyridine, triazoles and imidazo[2,1-a]isoidole.	Nitrogen	416-437	phosphodiesterase 10A	Homo sapiens	14-20
31874060-2	2020	Inhibition of PDE10A represents a molecular target in the treatment of conditions that would benefit from the increase of the level of cAMP and/or cGMP such as neurological and psychiatric disorders, cancer, and diabetes.Areas covered: The present article reviews the patent literature on PDE10A inhibitors (PDE10AIs) from 2014 to present and PDE10AI chemotypes from different chemical classes: heteroaryl- and aryl-nitrogen-heterocyclic compounds, unsaturated nitrogen-heterocyclic compounds with specific substituents such as pyrazolopyrimidine, aryloxymethyl cyclopropane, pyridizinone, imidazopyridine, triazoles and imidazo[2,1-a]isoidole.	Nitrogen	416-437	phosphodiesterase 10A	Homo sapiens	289-295
31286572-5	2020	An electrochemical enzymatic system based on CYP3A4 immobilized on a screen-printed electrode was used to show that abiraterone acts as a competitive inhibitor toward erythromycin N-demethylase activity of CYP3A4 (apparent Ki  = 8.1 +- 1.2 muM), while erythromycin and its products of enzymatic metabolism do not affect abiraterone N-oxidation by CYP3A4.	Nitrogen	180-181	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	45-51
32149536-3	2020	Serum haptoglobin, a highly sialylated glycoprotein with four N-glycosylation sites, has gained considerable attention due to its potential as a signature molecule to display aberrant glycosylation in inflammatory disorders and various types of cancer.	Nitrogen	62-63	haptoglobin	Homo sapiens	6-17
31286572-5	2020	An electrochemical enzymatic system based on CYP3A4 immobilized on a screen-printed electrode was used to show that abiraterone acts as a competitive inhibitor toward erythromycin N-demethylase activity of CYP3A4 (apparent Ki  = 8.1 +- 1.2 muM), while erythromycin and its products of enzymatic metabolism do not affect abiraterone N-oxidation by CYP3A4.	Nitrogen	180-181	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	206-212
31286572-5	2020	An electrochemical enzymatic system based on CYP3A4 immobilized on a screen-printed electrode was used to show that abiraterone acts as a competitive inhibitor toward erythromycin N-demethylase activity of CYP3A4 (apparent Ki  = 8.1 +- 1.2 muM), while erythromycin and its products of enzymatic metabolism do not affect abiraterone N-oxidation by CYP3A4.	Nitrogen	180-181	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	206-212
31845472-7	2020	We found that iodinated peptide with amine in the N and amide in the C termini, respectively, was the best inhibitor of Abeta fibers formation.	Nitrogen	50-51	amyloid beta precursor protein	Homo sapiens	120-125
31924668-0	2020	FSGS-Causing INF2 Mutation Impairs Cleaved INF2 N-Fragment Functions in Podocytes.	Nitrogen	14-15	inverted formin 2	Homo sapiens	43-47
31924668-14	2020	CONCLUSIONS: INF2 is cleaved into an N-terminal DID-containing fragment and a C-terminal DAD-containing fragment.	Nitrogen	2-3	inverted formin 2	Homo sapiens	13-17
31862363-0	2020	Identification of unexplored substrates of the serine protease, thrombin, using N-terminomics strategy.	Nitrogen	80-81	coagulation factor II, thrombin	Homo sapiens	47-62
31862363-0	2020	Identification of unexplored substrates of the serine protease, thrombin, using N-terminomics strategy.	Nitrogen	80-81	coagulation factor II, thrombin	Homo sapiens	64-72
31862363-4	2020	The purpose of our study was to identify hitherto unreported substrates of thrombin from human plasma using a N-terminomics protease substrate identification method.	Nitrogen	110-111	coagulation factor II, thrombin	Homo sapiens	75-83
31639410-3	2020	In nitrogen-mustard-exposed mouse skin, we found p-ERK activation increased Fra-1 and FosB.	Nitrogen	3-11	mitogen-activated protein kinase 1	Mus musculus	51-54
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	LIF receptor subunit alpha	Homo sapiens	55-90
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	LIF receptor subunit alpha	Homo sapiens	92-96
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	signal transducer and activator of transcription 3	Homo sapiens	187-192
32029150-0	2020	Research Note: Effect of selection for body weight on the adipogenic conversion of turkey myogenic satellite cells by Syndecan-4 and its covalently attached N-glycosylation chains.	Nitrogen	9-10	syndecan-4	Meleagris gallopavo	118-128
32029150-5	2020	The objective of the current study was to determine if syndecan-4, and syndecan-4 N-glycosylation and heparan sulfate chain levels altered the conversion of satellite cells to an adipogenic cell fate and if growth selection affected the response of the satellite cells.	Nitrogen	82-83	syndecan-4	Meleagris gallopavo	71-81
32029150-8	2020	Results from this study demonstrated that wild type levels of syndecan-4 and its covalently attached N-glycosylation chains play a key role in regulating the conversion of pectoralis major muscle satellite cells to an adipogenic lineage while selection for body weight was not a major contributing factor in this conversion.	Nitrogen	101-102	syndecan-4	Meleagris gallopavo	62-72
31585024-10	2020	In contrast, only the read-through protein is functional with E60X- and G542X-CFTR, although abundant N-terminus truncated proteins due to reinitiation of translation were detected in E60X-CFTR.	Nitrogen	102-103	CF transmembrane conductance regulator	Homo sapiens	189-193
32011206-0	2020	A de novo nonsense mutation in the N-terminal of ligand-binding domain of NR2F1 gene provoked a milder phenotype of BBSOAS.	Nitrogen	35-36	nuclear receptor subfamily 2 group F member 1	Homo sapiens	74-79
32011206-0	2020	A de novo nonsense mutation in the N-terminal of ligand-binding domain of NR2F1 gene provoked a milder phenotype of BBSOAS.	Nitrogen	35-36	nuclear receptor subfamily 2 group F member 1	Homo sapiens	116-122
31928660-0	2020	Preferential assimilation of NH4+ over NO3- in tea plant associated with genes involved in nitrogen transportation, utilization and catechins biosynthesis.	Nitrogen	91-99	NBL1, DAN family BMP antagonist	Homo sapiens	39-42
31639410-5	2020	In nitrogen-mustard-exposed cultured immortalized human keratinocytes (HaCaT cells), Fra-1 in the nucleus functioned as an inhibitor of inflammatory cytokine interleukin (IL)-8.	Nitrogen	3-11	C-X-C motif chemokine ligand 8	Homo sapiens	158-176
32385215-2	2020	The magnetic field could enhance the denitrification efficiency, especially for wastewater with low C/N ratios, and the average removal efficiencies of NO3--N increased by 6.58%.	Nitrogen	102-103	NBL1, DAN family BMP antagonist	Homo sapiens	152-155
30902024-14	2020	These findings demonstrate that the relative CYP3A4, CYP2B6, and CYP2C19 involvement in meperidine N-demethylation depends on the enzyme activities in individual human liver microsomal samples.	Nitrogen	99-100	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	45-51
31996710-6	2020	pH-dependent OGR1-mediated signalling led to a significant upregulation in the ER stress markers, binding immunoglobulin protein (BiP) and phospho-inositol required 1alpha (IRE1alpha), which was reversed by a novel OGR1 inhibitor and a c-Jun N-terminal kinase (JNK) inhibitor.	Nitrogen	242-243	heat shock protein family A (Hsp70) member 5	Homo sapiens	98-128
32005949-1	2020	The aim is to devise a new short-term intensive insulin therapy (N-SIIT) based on the concept of "treat to target" to avoid hypoglycaemia and was applied it to various diabetic state.	Nitrogen	65-66	insulin	Homo sapiens	48-55
32013195-1	2020	Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal acetyltransferase (NAT) that catalyzes the acetylation of N-termini of newly synthesized peptides.	Nitrogen	41-42	N-alpha-acetyltransferase 15, NatA auxiliary subunit	Homo sapiens	111-139
32013195-1	2020	Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal acetyltransferase (NAT) that catalyzes the acetylation of N-termini of newly synthesized peptides.	Nitrogen	41-42	N-alpha-acetyltransferase 15, NatA auxiliary subunit	Homo sapiens	141-144
31616924-6	2020	Plasma APOE held more abundant (20.5%) N-terminal (Thr8) sialylated core 1 (Neu5Acalpha2-3Galbeta1-3GalNAcalpha1-) glycosylation compared to CSF APOE (0.1%).	Nitrogen	39-40	apolipoprotein E	Homo sapiens	7-11
30902024-8	2020	The catalytic efficiency (kcat/Km) for meperidine N-demethylation was similar between recombinant CYP2B6 and CYP2C19, but markedly lower by CYP3A4.	Nitrogen	50-51	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	140-146
32005679-4	2020	The EGFR signal activated cJun/cJun N-terminal kinase and reduced interferon regulatory factor-1; the former increased CCL22, which recruits CD4+ regulatory T cells, and the latter decreased CXCL10 and CCL5, which induce CD8+ T cell infiltration.	Nitrogen	36-37	epidermal growth factor receptor	Homo sapiens	4-8
31964701-6	2020	actin isoforms with the desired N-end via ubiquitin fusion and 2. mammalian enzymes that promote acetylation and methylation.	Nitrogen	32-33	actin	Saccharomyces cerevisiae S288C	0-5
32039338-0	2020	Combined Enzyme- and Transition Metal-Catalyzed Strategy for the Enantioselective Syntheses of Nitrogen Heterocycles: (-)-Coniine, DAB-1, and Nectrisine.	Nitrogen	95-103	DAB adaptor protein 1	Homo sapiens	131-136
31663253-4	2020	SC-SC sorption of N 2 , CO 2 , Xe, and AcMe by p- G 2 BDS is explored under various conditions and X-ray diffraction provides a measurement of the high pressure Xe and CO 2 sorption isotherms.	Nitrogen	18-21	delta like non-canonical Notch ligand 1	Homo sapiens	47-53
31980684-4	2020	The mass spectrometry analysis revealed three extra amino acids at the N-Terminal end of ApoA-Ib that were not present in the standard plasmatic form of ApoA-I.	Nitrogen	71-72	apolipoprotein A1	Homo sapiens	89-95
32063885-6	2019	Results: In postmenopausal women, large N-mid fragment of osteocalcin (N-MID osteocalcin) was negatively associated with probable NASH (P for trend &lt; 0.001).	Nitrogen	40-41	bone gamma-carboxyglutamate protein	Homo sapiens	58-69
31864635-6	2020	The N-CNTC-coated fiber was then used to identify polychlorinated biphenyls (PCBs) with wide linear range (0.3-1000.0 ng L-1), low limits of detection (0.10-0.22 ng L-1), good repeatability (intra-day, 2.6-3.8%; inter-day, 3.3-4.8%), and good reproducibility (&lt;8.6%).	Nitrogen	4-5	immunoglobulin kappa variable 1-16	Homo sapiens	121-124
31864635-6	2020	The N-CNTC-coated fiber was then used to identify polychlorinated biphenyls (PCBs) with wide linear range (0.3-1000.0 ng L-1), low limits of detection (0.10-0.22 ng L-1), good repeatability (intra-day, 2.6-3.8%; inter-day, 3.3-4.8%), and good reproducibility (&lt;8.6%).	Nitrogen	4-5	immunoglobulin kappa variable 1-16	Homo sapiens	165-168
31854422-2	2020	Mechanistic investigation based on 31P NMR tracking experiments unveils that the reaction is initiated with the in situ formation of the modified Huisgen zwitterions from arylazocarboxylates and PPh3 and proceeds via a nitrogen to nitrogen ester group migration process.	Nitrogen	219-227	caveolin 1	Homo sapiens	195-199
31624846-0	2020	AKINbeta1, a regulatory subunit of SnRK1, regulates organic acid metabolism and acts as a global regulator of genes involved in carbon, lipid and nitrogen metabolism.	Nitrogen	146-154	5'-AMP-activated protein kinase beta-2 subunit protein	Arabidopsis thaliana	0-9
31830412-4	2020	HypX has a bipartite structure composed of an N-terminal module similar to N10-formyl-THF transferases and a C-terminal module homologous to enoyl-CoA hydratases/isomerases.	Nitrogen	46-47	HPT	Homo sapiens	0-4
31998401-7	2020	Fatty acid synthesis in pigs from the H-BCAA group was lower than those from the N-BCAA group with the down-regulation of lipogenic genes (ACACA, FASN, PPAR-r, SREBP-1c in ventral and dorsal fat, SREBP-1c in liver) and up-regulation of lipolysis genes (HSL, ATGL, CPT-1A, FABP4 in ventral fat, HSL in liver) (P &lt; 0.05).	Nitrogen	81-82	acetyl-CoA carboxylase alpha	Sus scrofa	139-144
31998401-8	2020	Similarly, fatty acid synthesis in pigs from the L-BCAA group was also lower than those from the N-BCAA group with the decrease of lipogenic genes (ACACA in ventral, ACACA and FASN in dorsal fat, ACACA, FASN, SREBP-1c in liver) and the increase of lipolysis genes (ATGL, CPT-1A CD36, FABP4 in ventral fat and HSL, ATGL, CPT-1A in dorsal fat, CPT-1A) (P &lt; 0.05).	Nitrogen	97-98	acetyl-CoA carboxylase alpha	Sus scrofa	148-153
31854422-2	2020	Mechanistic investigation based on 31P NMR tracking experiments unveils that the reaction is initiated with the in situ formation of the modified Huisgen zwitterions from arylazocarboxylates and PPh3 and proceeds via a nitrogen to nitrogen ester group migration process.	Nitrogen	231-245	caveolin 1	Homo sapiens	195-199
31694953-5	2020	The N-terminal sequence of BFLF2 is less conserved to that of alpha- and beta herpesvirus homologs.	Nitrogen	4-5	nuclear egress lamina protein	Human gammaherpesvirus 4	27-32
31963914-0	2020	Sustainable Biomass Glucose-Derived Porous Carbon Spheres with High Nitrogen Doping: As a Promising Adsorbent for CO2/CH4/N2 Adsorptive Separation.	Nitrogen	68-76	chimerin 2	Homo sapiens	118-124
31963646-6	2020	This work was based on the crystal structure of the BTLA/HVEM complex showing that BTLA binds the N-terminal cysteine-rich domain of HVEM.	Nitrogen	98-99	TNF receptor superfamily member 14	Homo sapiens	57-61
31963646-6	2020	This work was based on the crystal structure of the BTLA/HVEM complex showing that BTLA binds the N-terminal cysteine-rich domain of HVEM.	Nitrogen	98-99	TNF receptor superfamily member 14	Homo sapiens	133-137
31756331-11	2020	The effect of SRGG phosphorylation on the interactions of Nop1p remains unknown yet was predicted to cause a structural disorder-to-order transition in the Nop1p N-terminal domain.	Nitrogen	58-59	rRNA methyltransferase NOP1	Saccharomyces cerevisiae S288C	156-161
31778897-4	2020	GADD34 N-terminal ER-binding-helix amino acid region 1-192 alone was found to be sufficient for the inhibition of HIV-1 replication whereas protein-phosphatase -1-binding domain and eIF-2alpha-phosphatase activity of GADD34 were not crucial for anti-HIV-1 activity.	Nitrogen	7-8	protein phosphatase 1 regulatory subunit 15A	Homo sapiens	0-6
31880458-4	2020	The results demonstrate that the deprotonated hydroxyl group in the chromophore and the nitrogen atom ND1 in His148 are charged negatively and positively, respectively, forming an ion pair.	Nitrogen	88-96	mitochondrially encoded NADH dehydrogenase 1	Homo sapiens	102-105
31953488-4	2020	Truncated p53 mutants modulated droplet formation, suggesting the importance of multivalent electrostatic interactions among the N-terminal and C-terminal domains.	Nitrogen	129-130	tumor protein p53	Homo sapiens	10-13
31778897-4	2020	GADD34 N-terminal ER-binding-helix amino acid region 1-192 alone was found to be sufficient for the inhibition of HIV-1 replication whereas protein-phosphatase -1-binding domain and eIF-2alpha-phosphatase activity of GADD34 were not crucial for anti-HIV-1 activity.	Nitrogen	7-8	protein phosphatase 1 regulatory subunit 15A	Homo sapiens	217-223
31936901-5	2020	Here, we present a quantitative characterization of the effect of the T42A mutation on the binding of the N-terminal SH2 domain of SHP2 with a peptide mimicking Gab2, a fundamental interaction that triggers the activation of the phosphatase in the cellular environment.	Nitrogen	106-107	GRB2 associated binding protein 2	Homo sapiens	161-165
31787665-0	2020	N-glycosylation of Rim21 at an unconventional site fine-tunes its behavior in the plasma membrane.	Nitrogen	0-1	Rim21p	Saccharomyces cerevisiae S288C	19-24
31787665-2	2020	Rim21 is known to undergo N-glycosylation, but the site and function of the glycosylation modification is not known.	Nitrogen	26-27	Rim21p	Saccharomyces cerevisiae S288C	0-5
31787665-3	2020	Using a systematic mutation analysis, we found that Rim21 is N-glycosylated at an unconventional motif located in the N-terminal extracellular region.	Nitrogen	61-62	Rim21p	Saccharomyces cerevisiae S288C	52-57
31787665-3	2020	Using a systematic mutation analysis, we found that Rim21 is N-glycosylated at an unconventional motif located in the N-terminal extracellular region.	Nitrogen	118-119	Rim21p	Saccharomyces cerevisiae S288C	52-57
31787665-4	2020	The Rim21 mutant protein that failed to receive N-glycosylation showed prolonged protein lifetime compared to that of WT Rim21 protein.	Nitrogen	48-49	Rim21p	Saccharomyces cerevisiae S288C	4-9
31787665-9	2020	Collectively, N-glycosylation of Rim21 is not indispensable for its activity as a sensor protein, but modulates the residence of Rim21 protein to some microdomains within the plasma membrane with distinct lipid conditions, thereby affecting its turnover.	Nitrogen	14-15	Rim21p	Saccharomyces cerevisiae S288C	33-38
31787665-9	2020	Collectively, N-glycosylation of Rim21 is not indispensable for its activity as a sensor protein, but modulates the residence of Rim21 protein to some microdomains within the plasma membrane with distinct lipid conditions, thereby affecting its turnover.	Nitrogen	14-15	Rim21p	Saccharomyces cerevisiae S288C	129-134
31754694-0	2020	Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.	Nitrogen	25-26	timeless circadian regulator	Homo sapiens	52-60
31941025-3	2020	cJun N-terminal kinase (JNK), a member of the MAPK family, plays a central role in HCC pathogenesis.	Nitrogen	5-6	mitogen-activated protein kinase 8	Homo sapiens	24-27
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	32-33	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	196-201
31633754-8	2020	Treatment of N-MFs with a combination of recombinant human MMP-7, -9 and -10 significantly decreased mPD-L1.	Nitrogen	13-14	CD274 antigen	Mus musculus	101-107
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	32-33	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	207-213
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	130-131	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	196-201
31854936-4	2020	After adding 700 mg L-1 glucose to the influent, due to the synergistic effect of denitrification and anammoxidation, the combined process achieved its best nitrogen removal performance at a reflux ratio of 2.0 and hydraulic retention time (HRT) of 2.2 days.	Nitrogen	157-165	L1 cell adhesion molecule	Homo sapiens	20-23
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	130-131	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	207-213
31901076-0	2020	Erratum for Research Article "Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-beta" by J. Li, M. Ritelli, C. S. Ma, G. Rao, T. Habib, E. Corvilain, S. Bougarn, S. Cypowyj, L. Grodecka, R. Levy, V. Beziat, L. Shang, K. Payne, D. T. Avery, M. Migaud, S. Boucherit, S. Boughorbel, A. Guennoun, M. Chrabieh, F. Rapaport, B. Bigio, Y. Itan, B. Boisson, V. Cormier-Daire, D. Syx, F. Malfait, N.	Nitrogen	120-121	transforming growth factor beta 1	Homo sapiens	160-168
31913260-5	2020	In addition, we found that SGK196 N-glycosylation performs the regulatory function through the PI3K/AKT/GSK3beta signaling pathway.	Nitrogen	34-35	AKT serine/threonine kinase 1	Homo sapiens	100-103
31808343-6	2020	Using site-specific binding titrations, we show that the recruitment of Abeta oligomers primarily occurs via the electrostatic interaction between the N-terminal intrinsically disordered region of PrP and Abeta oligomers.	Nitrogen	151-152	amyloid beta precursor protein	Homo sapiens	72-77
31808343-6	2020	Using site-specific binding titrations, we show that the recruitment of Abeta oligomers primarily occurs via the electrostatic interaction between the N-terminal intrinsically disordered region of PrP and Abeta oligomers.	Nitrogen	151-152	prion protein	Homo sapiens	197-200
31808343-6	2020	Using site-specific binding titrations, we show that the recruitment of Abeta oligomers primarily occurs via the electrostatic interaction between the N-terminal intrinsically disordered region of PrP and Abeta oligomers.	Nitrogen	151-152	amyloid beta precursor protein	Homo sapiens	205-210
31829615-3	2020	NGR peptide was first modified with N3-NOtB2 and then conjugated to BCN-PEG4-c(RGDyK) via copper free click chemistry.	Nitrogen	36-44	reticulon 4 receptor	Mus musculus	0-3
32021253-3	2020	Besides, protein levels of p-JNK1 and c-Jun N-terminal kinases (JNK) in metformin-treated TPC-1 cells were detected by Western blot.	Nitrogen	30-31	two pore segment channel 1	Homo sapiens	90-95
31822871-5	2020	Calculations for the density of states and electron orbitals confirm that the metallicity originates from the sp2-hybridized B and N atoms, forming 1D linear conductive channels in the 3D network.	Nitrogen	131-132	Sp2 transcription factor	Homo sapiens	110-113
32206282-0	2020	Readily accessible sp3-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality.	Nitrogen	67-75	Sp3 transcription factor	Homo sapiens	19-22
31642335-5	2020	In addition, the N-terminus (amino acids 43-86) of PIAS3 bound nNOS directly.	Nitrogen	17-18	protein inhibitor of activated STAT 3	Homo sapiens	51-56
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	amyloid beta precursor protein	Homo sapiens	534-540
32933312-4	2020	Both EASM and Tan-IIA significantly decreased serum uric acid (SUA), serum creatinine (SCR), urine uric acid (UUA), and increased urine creatinine (UCR), and blood urea nitrogen (BUN) levels in experimental UAN mice.	Nitrogen	169-177	ATPase, class II, type 9A	Mus musculus	18-21
31622777-8	2020	The peak value of the bone formation marker N-terminal propeptide of type 1 procollagen (P1NP) peaked at higher levels during GIP (109 +- 6.7% of baseline) than during GIP(3-30)NH2 infusion (101 +- 8.9%) (P = 0.049) and GIP suppressed PTH levels compared to GIP(3-30)NH2 alone (P = 0.0158).	Nitrogen	44-45	gastric inhibitory polypeptide	Homo sapiens	126-129
31619063-7	2020	AIP1B, which lacks the N-terminal pleckstrin homology domain of AIP1A, localized to the mitochondria and augmented TNF (tumor necrosis factor)-induced mitochondrial reactive oxygen species generation and EC activation.	Nitrogen	23-24	DAB2 interacting protein	Homo sapiens	0-5
31759978-2	2020	Here, we hypothesized that X1 and sorafenib induce mitochondrial dysfunction by increasing ROS formation and activating c-Jun N-terminal kinases (JNKs), leading to translocation of activated JNK to mitochondria.	Nitrogen	126-127	mitogen-activated protein kinase 8	Homo sapiens	146-149
31622777-8	2020	The peak value of the bone formation marker N-terminal propeptide of type 1 procollagen (P1NP) peaked at higher levels during GIP (109 +- 6.7% of baseline) than during GIP(3-30)NH2 infusion (101 +- 8.9%) (P = 0.049) and GIP suppressed PTH levels compared to GIP(3-30)NH2 alone (P = 0.0158).	Nitrogen	44-45	parathyroid hormone	Homo sapiens	235-238
31733588-1	2020	The N-terminal von Willebrand domain of Ku80 supports interactions with a Ku binding motif (KBM) that has been identified in at least three other DNA repair proteins: the non-homologous end joining (NHEJ) scaffold APLF, the modulator of retrovirus infection, MRI, and the Werner syndrome protein (WRN).	Nitrogen	4-5	aprataxin and PNKP like factor	Homo sapiens	214-218
31676226-8	2020	Moreover, pretreatment (72 hours) with 10 nM DPN to the cell line of microglia (N9) or astrocyte (MA1800) significantly increased the cell viability and decreased the cell apoptosis and damage after OGD-R injury, and significantly inhibited the expression of NF-kappaB and proinflammatory cytokines.	Nitrogen	80-82	nuclear factor kappa B subunit 1	Homo sapiens	259-268
31705797-2	2020	DESIGN: The study aimed to explore relations between IGF-I and changes in surrogate markers of cardiovascular disease including carotid intima-media thickness (IMT), left ventricular mass index (LVMI) and N-terminal pro-brain natriuretic peptide (NT-proBNP).	Nitrogen	5-6	insulin like growth factor 1	Homo sapiens	53-58
31494931-7	2020	Furthermore, MGAT1 promotes complex N-glycosylation of glucose transporter 1 (Glut1) and increases Glut1 protein levels.	Nitrogen	36-37	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	13-18
31838698-7	2020	The relatively large surface area as estimated from N2 adsorption makes the nanopowders very favorable for the uptake Cd(II), Cr (IV), Co (II) and Ni(II) from aqueous solution.	Nitrogen	52-54	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	135-153
31650666-0	2020	GATA-type transcriptional factor Gat1 regulates nitrogen uptake and polymalic acid biosynthesis in polyextremotolerant fungus Aureobasidium pullulans.	Nitrogen	48-56	solute carrier family 6 member 1	Homo sapiens	33-37
31650666-2	2020	In this study, a GATA-family transcriptional factor, Gat1, which regulates nitrogen uptake and PMA biosynthesis, was investigated.	Nitrogen	75-83	solute carrier family 6 member 1	Homo sapiens	53-57
31650666-4	2020	Comparative transcriptome analysis of wide-type and mutant strains ( gat1 and OE::gat1) revealed that 23 common differentially expressed genes were related to oxidative phosphorylation, ribosome biogenesis, and nitrogen metabolism.	Nitrogen	211-219	solute carrier family 6 member 1	Homo sapiens	69-73
31650666-4	2020	Comparative transcriptome analysis of wide-type and mutant strains ( gat1 and OE::gat1) revealed that 23 common differentially expressed genes were related to oxidative phosphorylation, ribosome biogenesis, and nitrogen metabolism.	Nitrogen	211-219	solute carrier family 6 member 1	Homo sapiens	82-86
31650666-5	2020	Under nitrogen-limited stress, regardless of the preferred nitrogen (glutamine, Gln) or non-preferred nitrogen (proline, Pro), 70% of Gat1 in the cells was located in the nucleus-cytoplasm, which resulted in an increase in nitrogen uptake and PMA biosynthesis regulation.	Nitrogen	6-14	solute carrier family 6 member 1	Homo sapiens	134-138
31650666-6	2020	Quantitative RT-PCR revealed that glucosekinase (GLK) in the glycolytic pathway and malate synthase (MLS) in the glyoxylate shunt pathway may be cross-regulated by Gat1 and nitrogen concentration (Gln or Pro), Therefore, glk was overexpressed in mutant strain (OE::gat1), which resulted in an increased PMA titer and yield of 12.6% and 13.0%, respectively.	Nitrogen	173-181	solute carrier family 6 member 1	Homo sapiens	265-269
31650666-7	2020	These findings indicate that Gat1 may play an important role in the dual-regulation of the nitrogen and carbon metabolisms in PMA biosynthesis.	Nitrogen	91-99	solute carrier family 6 member 1	Homo sapiens	29-33
31816576-7	2020	Meanwhile, the five isosteroid alkaloids significantly inhibited the phosphorylated activation of mitogen activated protein kinase (MAPK) signaling pathways, including extracellular signal-regulated kinase (ERK1/2), p38 MAPK and c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK).	Nitrogen	235-236	mitogen-activated protein kinase 1	Mus musculus	132-136
33191974-6	2020	The best nitrogen rate for all P and K levels was 60 kg ha-1, which gave grain yield of 5 t ha-1 .	Nitrogen	9-17	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	56-60
31800161-5	2020	Decreased levels of renal KLF4 were positively correlated with dietary-induced renal dysfunction, including increased levels of creatinine and blood urea nitrogen.	Nitrogen	154-162	Kruppel-like factor 4 (gut)	Mus musculus	26-30
31586599-3	2020	We report a X-ray co-crystal structure at 1.5 A resolution of an N-terminal fragment of RHAU bound to the exposed tetrad of a parallel-stranded G-quadruplex.	Nitrogen	65-66	DEAH-box helicase 36	Homo sapiens	88-92
33191974-6	2020	The best nitrogen rate for all P and K levels was 60 kg ha-1, which gave grain yield of 5 t ha-1 .	Nitrogen	9-17	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	92-96
33191974-9	2020	The EORN was 61 kg ha-1, 32% less than the recommended 90 kg N ha-1 for maize production in the semi-deciduous forest zone of Ghana.	Nitrogen	7-8	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	19-23
31595465-11	2020	Here we provide an overview of the important enzymes such as nitrate reductase, nitrite reductase, glutamine synthase, GOGAT, glutamate dehydrogenase, and alanine aminotransferase that are involved in nitrogen metabolism.	Nitrogen	201-209	glutamate-ammonia ligase	Homo sapiens	99-117
31595477-2	2020	Many plant species depend on the availability of NO3 - as the main source of nitrogen (N).	Nitrogen	77-85	NBL1, DAN family BMP antagonist	Homo sapiens	49-52
31595466-2	2020	Plants assimilate inorganic form of N [nitrate (NO3 -), nitrite (NO2 -) or ammonium (NH4 +)] and incorporate into amino acids.	Nitrogen	36-37	NBL1, DAN family BMP antagonist	Homo sapiens	48-51
29189096-2	2020	RhoU and RhoV are Rho GTPases that have some atypical properties compared with classical Rho family members, such as the presence of N- and C-terminal extension regions, unusual GDP/GTP cycling and post-translational modification by palmitoylation but not prenylation.	Nitrogen	133-134	ras homolog family member U	Homo sapiens	0-4
31715212-3	2020	In this study, N-methylated peptide inhibitors F-N(Me)H-L, V-N(Me)F-R and R-N(Me)V-Y were synthesized against ACE, NEP and APN respectively, using their respective physiological substrates.	Nitrogen	15-16	angiotensin I converting enzyme	Rattus norvegicus	110-113
31746288-3	2020	In this connection, we have earlier reported the immunotherapeutic potential of N-formylated N-terminal peptide of glutamine synthetase of Mycobacterim tuberculosis H37Rv (Mir SA and Sharma S, 2014).	Nitrogen	80-81	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	115-135
31746288-4	2020	Now in the present study, we investigated the immunotherapeutic effect of N-terminally formylated internal peptide "f-MLLLPD" of mycobacterial glutamine synthetase (Rv2220) in mouse model of tuberculosis.	Nitrogen	0-1	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	143-163
31600539-6	2020	Removal of N-glycosylation on epidermal growth factor (EGFR) and integrin beta3, two proposed hCMV receptors, blocked their interaction with hCMV glycoproteins B and H. It also suppressed activation of these receptors and downstream integrin beta3/Src signaling.	Nitrogen	11-12	integrin subunit beta 3	Homo sapiens	65-79
31600539-6	2020	Removal of N-glycosylation on epidermal growth factor (EGFR) and integrin beta3, two proposed hCMV receptors, blocked their interaction with hCMV glycoproteins B and H. It also suppressed activation of these receptors and downstream integrin beta3/Src signaling.	Nitrogen	11-12	integrin subunit beta 3	Homo sapiens	233-247
31600539-6	2020	Removal of N-glycosylation on epidermal growth factor (EGFR) and integrin beta3, two proposed hCMV receptors, blocked their interaction with hCMV glycoproteins B and H. It also suppressed activation of these receptors and downstream integrin beta3/Src signaling.	Nitrogen	11-12	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	248-251
31997699-3	2020	The N-terminus of DHODH consists of a signal peptide for mitochondrial import (MS), a transmembrane domain (TM), followed by a microdomain which interacts with the lipids of the IMM and has been proposed to form the binding site for ubiquinone Q10.	Nitrogen	4-5	dihydroorotate dehydrogenase (quinone)	Homo sapiens	18-23
31558800-2	2020	The oncogenic potential of BRAF fusions has been attributed to the loss of critical N-terminal domains that mediate BRAF autoinhibition.	Nitrogen	84-85	B-Raf proto-oncogene, serine/threonine kinase	Homo sapiens	27-31
31558800-2	2020	The oncogenic potential of BRAF fusions has been attributed to the loss of critical N-terminal domains that mediate BRAF autoinhibition.	Nitrogen	84-85	B-Raf proto-oncogene, serine/threonine kinase	Homo sapiens	116-120
29189096-2	2020	RhoU and RhoV are Rho GTPases that have some atypical properties compared with classical Rho family members, such as the presence of N- and C-terminal extension regions, unusual GDP/GTP cycling and post-translational modification by palmitoylation but not prenylation.	Nitrogen	133-134	ras homolog family member V	Homo sapiens	9-13
31149862-1	2020	Despite expanding knowledge on the structure and reactivity of human aldehyde oxidase (hAOX1) many drugs enter human studies only to be removed from further clinical trials due to aldehyde oxidase (AOX)-catalysed metabolism.In addition to oxidation of numerous N-heterocycles and aldehydes, hAOX1 is also important in amide hydrolysis and reductive reactions.This article reviews the evidence for hAOX1 polymorphism and other genetic factors which affect hAOX1 expression and which may lead to attenuated drug metabolism.Difficulties in the selection of appropriate in silico and in vitro models for predicting hAOX1 metabolism are considered in the context of its wide substrate specificity.	Nitrogen	261-262	aldehyde oxidase 1	Homo sapiens	69-85
31654960-3	2020	Excess N2 in hyporheic porewaters ranged from &lt;0.1 to 8.65 mg L-1 and was significantly higher in porewaters from the 1.3 m (ground water source) versus 0.3 m (mixed surface and ground water) depths.	Nitrogen	7-9	immunoglobulin kappa variable 1-16	Homo sapiens	65-68
31654960-4	2020	In deep groundwater wells (3-7 m), median excess N2 concentration was 5.39 mg L-1 (range = &lt;0.1-14.6 mg L-1).	Nitrogen	49-51	immunoglobulin kappa variable 1-16	Homo sapiens	78-81
31654960-5	2020	Excess N2 concentrations were inversely correlated with dissolved oxygen and NO3- concentrations suggesting denitrification as an important process in the dominantly anaerobic sediments.	Nitrogen	7-9	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
31149862-1	2020	Despite expanding knowledge on the structure and reactivity of human aldehyde oxidase (hAOX1) many drugs enter human studies only to be removed from further clinical trials due to aldehyde oxidase (AOX)-catalysed metabolism.In addition to oxidation of numerous N-heterocycles and aldehydes, hAOX1 is also important in amide hydrolysis and reductive reactions.This article reviews the evidence for hAOX1 polymorphism and other genetic factors which affect hAOX1 expression and which may lead to attenuated drug metabolism.Difficulties in the selection of appropriate in silico and in vitro models for predicting hAOX1 metabolism are considered in the context of its wide substrate specificity.	Nitrogen	261-262	aldehyde oxidase 1	Homo sapiens	87-92
31149862-1	2020	Despite expanding knowledge on the structure and reactivity of human aldehyde oxidase (hAOX1) many drugs enter human studies only to be removed from further clinical trials due to aldehyde oxidase (AOX)-catalysed metabolism.In addition to oxidation of numerous N-heterocycles and aldehydes, hAOX1 is also important in amide hydrolysis and reductive reactions.This article reviews the evidence for hAOX1 polymorphism and other genetic factors which affect hAOX1 expression and which may lead to attenuated drug metabolism.Difficulties in the selection of appropriate in silico and in vitro models for predicting hAOX1 metabolism are considered in the context of its wide substrate specificity.	Nitrogen	261-262	aldehyde oxidase 1	Homo sapiens	180-196
31149862-1	2020	Despite expanding knowledge on the structure and reactivity of human aldehyde oxidase (hAOX1) many drugs enter human studies only to be removed from further clinical trials due to aldehyde oxidase (AOX)-catalysed metabolism.In addition to oxidation of numerous N-heterocycles and aldehydes, hAOX1 is also important in amide hydrolysis and reductive reactions.This article reviews the evidence for hAOX1 polymorphism and other genetic factors which affect hAOX1 expression and which may lead to attenuated drug metabolism.Difficulties in the selection of appropriate in silico and in vitro models for predicting hAOX1 metabolism are considered in the context of its wide substrate specificity.	Nitrogen	261-262	aldehyde oxidase 1	Homo sapiens	88-91
32021415-2	2019	Our purpose is to study the effect of postoperative radiotherapy on patients with stage IIIA(N2) NSCLC with EGFR mutation.	Nitrogen	93-95	epidermal growth factor receptor	Homo sapiens	108-112
31902154-0	2019	EF-hand like Region in the N-terminus of Anoctamin 1 Modulates Channel Activity by Ca2+ and Voltage.	Nitrogen	27-28	anoctamin 1, calcium activated chloride channel	Mus musculus	41-52
31902154-4	2019	Here we show that EF-hand like region containing multiple acidic amino acids at the N-terminus of ANO1 is a putative site regulating the activity of ANO1 by Ca2+ and voltage.	Nitrogen	84-85	anoctamin 1, calcium activated chloride channel	Mus musculus	98-102
31902154-4	2019	Here we show that EF-hand like region containing multiple acidic amino acids at the N-terminus of ANO1 is a putative site regulating the activity of ANO1 by Ca2+ and voltage.	Nitrogen	84-85	anoctamin 1, calcium activated chloride channel	Mus musculus	149-153
31906058-5	2019	Besides, the overall difference of the soil water-stable aggregate content in 2-5 mm size range among nitrogen treatments was significant under the application of C10, which increased by 17.04%-33.04% compared with C0.	Nitrogen	102-110	homeobox C10	Homo sapiens	163-166
32021415-9	2019	EGFR-mutant group with stage IIIA(N2) NSCLC has a tendency of a higher survival than the wild-type EGFR group, but there was no significant difference for both groups.	Nitrogen	34-36	epidermal growth factor receptor	Homo sapiens	0-4
31889246-4	2019	RESULTS: During the 2015-2017 period, the average application rates of synthetic N for wheat and maize in upland fields of China were 222 and 197 kg ha-1, respectively.	Nitrogen	81-82	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	149-153
31905841-7	2019	siTNS3 treatment upregulated p16 and p21 levels and downregulated SOX2 expression and focal adhesion kinase, protein kinase B, and c-Jun N-terminal kinase phosphorylation.	Nitrogen	3-4	cyclin dependent kinase inhibitor 2A	Homo sapiens	29-32
31886770-5	2019	The flexible ATPase lobe, composed of helicase subunit Sth1, Arp7, Arp9 and Rtt102, is anchored to this core by the N-terminus of Sth1.	Nitrogen	116-117	Arp9p	Saccharomyces cerevisiae S288C	67-71
33479614-6	2020	This study establishes that CYP2D6-expressing live yeast cells can be a powerful tool for the enzymatic C-N, C-C bond cleavage of amino-acids.	Nitrogen	106-107	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	28-34
31769768-0	2019	Catalyst-free electrochemical decarboxylative cross-coupling of N-hydroxyphthalimide esters and N-heteroarenes towards C(sp3)-C(sp2) bond formation.	Nitrogen	96-110	Sp2 transcription factor	Homo sapiens	126-131
31769768-3	2019	In this work, we developed an electrochemical C(sp3)-C(sp2) coupling of N-hydroxyphthalimide esters and N-heteroarenes without any catalysts.	Nitrogen	104-118	Sp2 transcription factor	Homo sapiens	53-58
31878192-1	2019	Rpb11 subunit of RNA polymerase II of Eukaryotes is related to N-terminal domain of eubacterial alpha subunit and forms a complex with Rpb3 subunit analogous to prokaryotic alpha2 homodimer, which is involved in RNA polymerase assembly and promoter recognition.	Nitrogen	18-19	RNA polymerase II subunit J	Homo sapiens	0-5
31599159-5	2019	The ARH and macrodomain protein families, in stereospecific reactions, cleave ADP-ribose linkages to N- or O- containing functional groups; anomerization of alpha- to beta-forms (e.g. alpha-ADP-ribosyl-arginine to beta-ADP-ribose-(arginine) protein) may explain partial hydrolysis of ADP-ribosylated acceptors with an increase in content of ADP-ribosylated substrates.	Nitrogen	101-102	low density lipoprotein receptor adaptor protein 1	Homo sapiens	4-7
31599159-6	2019	Af1521 and ARH3 crystal structures with bound ADP-ribose revealed similar ADP-ribose-binding pockets with the catalytic residues of the ARH and macrodomain protein families in the N-terminal helix and loop.	Nitrogen	180-181	low density lipoprotein receptor adaptor protein 1	Homo sapiens	11-14
31869342-9	2019	Specifically, in LP, N/EM ratio was significantly higher in immunological responder patients (CD4>500/mmc at w24) when compared to immunological non responder (CD4 T cells <500/mmc at w24).	Nitrogen	21-22	CD4 molecule	Homo sapiens	94-97
31869342-10	2019	Finally, a multivariate analysis indicates that after 24w patients with N/EM ratio higher than 1.86 at w0 recovered 96 CD4 T cells more than those with N/EM ratio lower than 0.46.	Nitrogen	72-73	CD4 molecule	Homo sapiens	119-122
31856924-3	2019	Using a novel FGFR1-selective agonist (F2 V2) generated by deleting the N-terminal 26 amino acids of FGF2 we demonstrate polarizing signal transduction to favor FGFR1 abrogates FGF mediated inhibition of myelination but retains its ability to induce expression of pro-myelinating and immunomodulatory factors that include Cd93, Lif, Il11, Hbegf, Cxcl1 and Timp1.	Nitrogen	72-73	fibroblast growth factor receptor 1	Homo sapiens	14-19
31856924-3	2019	Using a novel FGFR1-selective agonist (F2 V2) generated by deleting the N-terminal 26 amino acids of FGF2 we demonstrate polarizing signal transduction to favor FGFR1 abrogates FGF mediated inhibition of myelination but retains its ability to induce expression of pro-myelinating and immunomodulatory factors that include Cd93, Lif, Il11, Hbegf, Cxcl1 and Timp1.	Nitrogen	72-73	fibroblast growth factor 2	Homo sapiens	101-105
31856924-3	2019	Using a novel FGFR1-selective agonist (F2 V2) generated by deleting the N-terminal 26 amino acids of FGF2 we demonstrate polarizing signal transduction to favor FGFR1 abrogates FGF mediated inhibition of myelination but retains its ability to induce expression of pro-myelinating and immunomodulatory factors that include Cd93, Lif, Il11, Hbegf, Cxcl1 and Timp1.	Nitrogen	72-73	fibroblast growth factor receptor 1	Homo sapiens	161-166
31857626-4	2019	In an angiotensin II (Ang II)-induced renal injury mouse model, we found that blocking AT1R and AT2R effectively mitigates Ang II-induced increases in necroptotic tubular epithelial cell percentages, necroptosis-related RIP3 and MLKL protein expression, serum creatinine and blood urea nitrogen levels, and tubular damage scores.	Nitrogen	286-294	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	22-28
31921534-6	2019	Results: An N-terminally cysteine modified GRPR antagonist (termed cystabn) was synthesised and shown to inhibit cell growth in vitro.	Nitrogen	12-13	gastrin releasing peptide receptor	Homo sapiens	43-47
31857626-4	2019	In an angiotensin II (Ang II)-induced renal injury mouse model, we found that blocking AT1R and AT2R effectively mitigates Ang II-induced increases in necroptotic tubular epithelial cell percentages, necroptosis-related RIP3 and MLKL protein expression, serum creatinine and blood urea nitrogen levels, and tubular damage scores.	Nitrogen	286-294	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	123-129
31852971-10	2019	The net ecosystem economic budget under optimal nitrogen rate is 252-604 $ ha-1 yr.-1 higher than other addition levels.	Nitrogen	48-56	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	75-79
31850845-1	2019	APOBEC3G (A3G), an enzyme expressed in primates with the potential to inhibit human immunodeficiency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with two domains, a catalytically active, weakly ssDNA binding C-terminal domain (CTD) and a catalytically inactive, strongly ssDNA binding N-terminal domain (NTD).	Nitrogen	157-158	apolipoprotein B mRNA editing enzyme catalytic subunit 3G	Homo sapiens	0-8
31850845-1	2019	APOBEC3G (A3G), an enzyme expressed in primates with the potential to inhibit human immunodeficiency virus type 1 (HIV-1) infectivity, is a single-stranded DNA (ssDNA) deoxycytidine deaminase with two domains, a catalytically active, weakly ssDNA binding C-terminal domain (CTD) and a catalytically inactive, strongly ssDNA binding N-terminal domain (NTD).	Nitrogen	157-158	apolipoprotein B mRNA editing enzyme catalytic subunit 3G	Homo sapiens	10-13
31714482-1	2019	Our previous studies showed that propane-2-sulfonic acid octadec-9-enyl-amide (N15), a novel peroxisome proliferator-activated receptors alpha and gamma (PPARalpha/gamma) dual agonist, protected against ischaemia-induced acute brain damage in mice and improved cognitive ability in the chronic phase of ischaemic stroke.	Nitrogen	79-82	peroxisome proliferator activated receptor alpha	Mus musculus	154-163
31861684-6	2019	The impaired G-actin incorporation was restored by the expression of full-length dysferlin as well as dysferlin N-terminal or C-terminal regions, both of which contain three C2 domains.	Nitrogen	112-113	dysferlin	Homo sapiens	102-111
31929901-0	2019	Association of Estimated Insulin Resistance with N-Terminal B-Type Natriuretic Peptide Concentration in Men with Metabolic Syndrome.	Nitrogen	49-50	insulin	Homo sapiens	25-32
31792183-9	2019	The homeodomain and N-terminal repression domain of Hhex were critical for inhibiting Foxp3 and other Treg signature genes.	Nitrogen	20-21	hematopoietically expressed homeobox	Mus musculus	52-56
31627810-0	2019	Nitrogen-doped carbon dots-V2O5 nanobelts sensing platform for sensitive detection of ascorbic acid and alkaline phosphatase activity.	Nitrogen	0-8	alkaline phosphatase, placental	Homo sapiens	104-124
31908483-2	2019	The binding of alpha5beta1 integrin with the tripeptide Arg-Gly-Asp (RGD) motif within the extracellular matrix protein fibronectin may be influenced by the alpha-1,6-fucose core or alpha-1,2-fucose and alpha-1,3/4-fucose peripheral N-glycan profiles.	Nitrogen	233-234	fibronectin 1	Homo sapiens	120-131
31874499-7	2019	Results: The differences between ISR group (n=52) and N-ISR group (n=355) were statistically significant in terms of diabetes history, IL-6, TNF-alpha, EATV ((150+-36) cm(3)vs(120+-40) cm(3),P=0.001)), bifurcation lesions, stent length and Gensini score (P&lt;0.05).	Nitrogen	54-55	interleukin 6	Homo sapiens	135-139
31629165-8	2019	Moreover, our study features developing new antioxidants and Nrf2 activators by introducing a sulfonyl group and nitrogen atom to the alpha,beta-unsaturated carbonyl entity in coumarin, rather than adding new functional groups or active fragments to coumarin itself.	Nitrogen	113-121	NFE2 like bZIP transcription factor 2	Rattus norvegicus	61-65
31722405-2	2019	Trl1 consists of three catalytic modules: an N-terminal ligase (LIG) domain; a central polynucleotide kinase (KIN) domain; and a C-terminal cyclic phosphodiesterase (CPD) domain.	Nitrogen	45-46	tRNA-Leu (anticodon AAG) 2-3	Homo sapiens	0-4
31818937-6	2019	The N-terminal domain of LiaX binds daptomycin and AMPs (such as human LL-37) and functions as an extracellular sentinel that activates the cell envelope stress response.	Nitrogen	4-5	cathelicidin antimicrobial peptide	Homo sapiens	71-76
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	CD4 molecule	Homo sapiens	129-132
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	CD4 molecule	Homo sapiens	274-277
31597760-9	2019	Residues 12-39 near the N-terminus of Nef have been described as interaction platform for the Nef-associated kinase complex (NAKC) and were recently identified as essential determinants for a broad range of Nef activities.	Nitrogen	24-25	S100 calcium binding protein B	Homo sapiens	38-41
31597760-9	2019	Residues 12-39 near the N-terminus of Nef have been described as interaction platform for the Nef-associated kinase complex (NAKC) and were recently identified as essential determinants for a broad range of Nef activities.	Nitrogen	24-25	S100 calcium binding protein B	Homo sapiens	94-97
31854604-4	2019	The average concentration of total nitrogen (TN) and total phosphorus (TP) reached 10.05 mg L-1 and 1.10 mg L-1, far exceeding the occurrence standard of eutrophication, which should be cause for concern.	Nitrogen	35-43	L1 cell adhesion molecule	Homo sapiens	92-101
31836717-6	2019	Ufd1 occupies a hydrophobic groove of the Mpr1/Pad1 N-terminal (MPN) domain of Npl4, which corresponds to the catalytic groove of the MPN domain of JAB1/MPN/Mov34 metalloenzyme (JAMM)-family deubiquitylating enzyme.	Nitrogen	52-53	proteasome regulatory particle lid subunit RPN11	Saccharomyces cerevisiae S288C	42-46
31890962-8	2019	Variants of MARV GP2 containing the N- and C-terminal halves ("MGP2-FNL" and "MGP2-CMT", respectively) have similar properties.	Nitrogen	36-37	glycoprotein 2	Homo sapiens	17-20
31767742-7	2019	Specifically, we find that the ocean can exhibit fundamental transitions in the species of nitrogen dominating the fixed-N inventory--from nitrate (NO3 -) to ammonium (NH4 +)--and that as this transition occurs, the inventory can partially collapse relative to P due to progressive spatial decoupling between the loci of NH4 + oxidation, NO3 - reduction, and nitrogen fixation.	Nitrogen	91-99	NBL1, DAN family BMP antagonist	Homo sapiens	148-151
31767742-7	2019	Specifically, we find that the ocean can exhibit fundamental transitions in the species of nitrogen dominating the fixed-N inventory--from nitrate (NO3 -) to ammonium (NH4 +)--and that as this transition occurs, the inventory can partially collapse relative to P due to progressive spatial decoupling between the loci of NH4 + oxidation, NO3 - reduction, and nitrogen fixation.	Nitrogen	91-99	NBL1, DAN family BMP antagonist	Homo sapiens	338-341
31690628-4	2019	Using phos-tag, a highly specific phosphate binding tag for separating phosphorylated proteins, we found that Gpa2 undergoes phosphorylation and that its level of phosphorylation is markedly increased upon nitrogen starvation.	Nitrogen	206-214	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	110-114
31702920-0	2019	Enantioselective Desymmetrization of Prochiral Cyclopentene-1,3-diones Triggered by Remote C(sp2)-N Bond Formation.	Nitrogen	98-99	Sp2 transcription factor	Homo sapiens	91-96
31288170-2	2019	Molecular dynamics simulations have successfully explained that CB-1 exhibits the best aggregate induced emission (AIE) activity due to the electron-deficient barbituric acid and the electron-rich carbazole exhibit a conformation which similar to pi-pi stacking, resulting in a strong electrostatic attraction between the molecules, meanwhile the N-atom substituent of the carbazole is n-propane plays a hydrophobic role.	Nitrogen	347-348	cannabinoid receptor 1	Homo sapiens	64-68
31604529-0	2019	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on beta-adrenoceptors.	Nitrogen	4-5	G protein-coupled receptor kinase 2	Homo sapiens	17-21
31604529-8	2019	Altogether, N-termini of GRK2 and GRK3 efficiently simulate RKIP effects on beta-AR signaling in HEK293 cells and in cardiomyocytes by their binding to beta2-AR and, thus, provide important insights for the development of new strategies to modulate beta2-AR signaling.	Nitrogen	12-13	G protein-coupled receptor kinase 2	Homo sapiens	25-29
31444548-7	2019	Somatic loss-of-function variants in the N-glycosylation pathway-associated SLC35A2 gene were found in mMCD/FCD1 cases.	Nitrogen	41-42	FECD2	Homo sapiens	108-112
31787052-11	2019	Similarly, the upregulation in Nox4 and Jun N-terminal kinase induced by Ang II administration was repressed by treatment with small interfering RNA targeting BubR1.	Nitrogen	31-32	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	73-79
31787052-11	2019	Similarly, the upregulation in Nox4 and Jun N-terminal kinase induced by Ang II administration was repressed by treatment with small interfering RNA targeting BubR1.	Nitrogen	31-32	BUB1B, mitotic checkpoint serine/threonine kinase	Mus musculus	159-164
31577132-5	2019	In comparison with the results obtained with other cathode materials (Ti, Cu, Co3O4, and Fe2O3) and obtained by other researchers, the new process shows a faster NO3--N reduction rate and much higher N2 selectivity.	Nitrogen	200-202	NBL1, DAN family BMP antagonist	Homo sapiens	162-165
31476564-5	2019	Backwash was conducted to BAF2 to improve nitrogen removal performance.	Nitrogen	42-50	BANF family member 2	Homo sapiens	26-30
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	152-153	acylaminoacyl-peptide hydrolase	Homo sapiens	28-31
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	152-153	acylaminoacyl-peptide hydrolase	Homo sapiens	188-191
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	152-153	acylaminoacyl-peptide hydrolase	Homo sapiens	188-191
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	152-153	acylaminoacyl-peptide hydrolase	Homo sapiens	188-191
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	317-318	acylaminoacyl-peptide hydrolase	Homo sapiens	28-31
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	317-318	acylaminoacyl-peptide hydrolase	Homo sapiens	188-191
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	317-318	acylaminoacyl-peptide hydrolase	Homo sapiens	188-191
31793906-6	2019	In contrast to the case for APH(2"")-Ia, where it was proposed that the enzyme-mediated hydrolysis of GTP is regulated by conformational changes in its N-terminal domain upon GTP binding, APH(2"")-IIa, APH(2"")-IIIa and APH(2"")-IVa show no such regulatory mechanism, primarily owing to structural differences in the N-terminal domains of these enzymes.	Nitrogen	317-318	acylaminoacyl-peptide hydrolase	Homo sapiens	188-191
31629202-10	2019	Increases in N2 production are suggested to be an effect of 1) enhanced nitrification that increases NO3- availability thus stimulating denitrification, and 2) Cd successfully sequestrating sulfide (yielding CdS), which allows for full denitrification to N2.	Nitrogen	13-15	NBL1, DAN family BMP antagonist	Homo sapiens	101-104
31605674-6	2019	The findings confirmed that CYP3A4 was a major contributor (at least 30% total metabolism) to all three of the possible N-dealkylation pathways; however, CYP2C9, and not CYP2C19, played a critical role in terbinafine metabolism and even exceeded CYP3A4 contributions for terbinafine N-demethylation.	Nitrogen	120-121	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	28-34
31605674-6	2019	The findings confirmed that CYP3A4 was a major contributor (at least 30% total metabolism) to all three of the possible N-dealkylation pathways; however, CYP2C9, and not CYP2C19, played a critical role in terbinafine metabolism and even exceeded CYP3A4 contributions for terbinafine N-demethylation.	Nitrogen	283-284	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	28-34
31605674-9	2019	Cytochrome P450 isozyme models accurately predicted the likelihood for terbinafine N-demethylation, but overestimated the likelihood for a minor N-denaphthylation pathway.	Nitrogen	83-84	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15
31605674-9	2019	Cytochrome P450 isozyme models accurately predicted the likelihood for terbinafine N-demethylation, but overestimated the likelihood for a minor N-denaphthylation pathway.	Nitrogen	145-146	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15
31573844-2	2019	We tested the hypothesis that primary human trophoblast cells and placental villous explants will be insulin responsive characterized by amino acid transport, Akt and Erk activity with maternal obesity and/or GDM.We evaluated term placentas from women with normal body mass index (BMI) (NORMAL, n=15), obesity (OB, n=11), normal BMI with GDM (N-GDM, n=11) and obesity with GDM (OB-GDM, n=11).	Nitrogen	287-288	insulin	Homo sapiens	101-108
31573844-5	2019	Insulin significantly increased amino acid transport activity to a similar degree in PHT cells isolated from NORMAL (+21%), N-GDM (+38%), OB (+37%) and OB-GDM (+35%) pregnancies.	Nitrogen	124-129	insulin	Homo sapiens	0-7
31319679-9	2019	In a model of acute renal injury induced by LPS, the Cx43+/- mouse exhibited a significantly lower level of blood interleukin-1beta (IL-1beta), blood urea nitrogen, and urinary protein, together with milder renal pathological changes and renal expression of NLRP3 and NOX4, as compared with the Cx43+/+ mouse.	Nitrogen	155-163	gap junction protein, alpha 1	Mus musculus	53-57
31557654-1	2019	Limited nitrogen removal capacity (mainly nitrate, NO3--N) remains a major challenge for subsurface wastewater infiltration system (SWIS).	Nitrogen	8-16	NBL1, DAN family BMP antagonist	Homo sapiens	51-54
31476564-7	2019	Nitrogen removal concentration improved from 8.6 mg/L to 22.8 mg/L via anammox pathway in BAF2, and total nitrogen removal concentration reached to 44.2 mg/L in two coupled BAFs during aeration process.	Nitrogen	0-8	BANF family member 2	Homo sapiens	90-94
31359515-1	2019	Nitrogen (N) losses from intensified agriculture are a major cause of global change, due to nitrate (NO3 - ) export and the eutrophication of aquatic systems as well as emissions of nitrous oxide (N2 O) into the atmosphere.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	101-104
31659706-1	2019	The article "Cu/N-codoped TiO2 prepared by the sol-gel method for phenanthrene removal under visible light irradiation," written by Zhenhua Zhao, Abduelrahman Adam Omer, Zhirui Qin, Salaheldein Osman, Liling Xia, and Rajendra Prasad Singh.	Nitrogen	16-17	forkhead box G1	Homo sapiens	177-180
31871426-10	2019	The overexpression or inhibition of IRF-1 effectively modulated caspase-1 activation, as well as macrophage lysis, expression of gasdermin D-N (GSDMD-N), production of IL-1beta and IL-18, and activation of NLRP3-ASC inflammasome, which were all inhibited by caspase-1 inhibitor.	Nitrogen	139-142	interferon regulatory factor 1	Homo sapiens	36-41
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	fms related receptor tyrosine kinase 3	Homo sapiens	23-27
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	fms related receptor tyrosine kinase 3	Homo sapiens	124-128
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	fms related receptor tyrosine kinase 3	Homo sapiens	124-128
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	226-231
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	281-286
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	fms related receptor tyrosine kinase 3	Homo sapiens	124-128
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	fms related receptor tyrosine kinase 3	Homo sapiens	124-128
31628732-4	2019	We linked the C-terminus of cyclooxygenase-1 (COX-1) to the N-terminus of the thromboxane A2 (TXA2 ) synthase (TXAS), through a 10-amino acid residue linker.	Nitrogen	60-61	prostaglandin-endoperoxide synthase 1	Homo sapiens	28-44
31628732-4	2019	We linked the C-terminus of cyclooxygenase-1 (COX-1) to the N-terminus of the thromboxane A2 (TXA2 ) synthase (TXAS), through a 10-amino acid residue linker.	Nitrogen	60-61	prostaglandin-endoperoxide synthase 1	Homo sapiens	46-51
31628732-4	2019	We linked the C-terminus of cyclooxygenase-1 (COX-1) to the N-terminus of the thromboxane A2 (TXA2 ) synthase (TXAS), through a 10-amino acid residue linker.	Nitrogen	60-61	thromboxane A synthase 1	Homo sapiens	111-115
31638225-11	2019	Function enrichment analysis revealed the genes in the ceRNA network that participated in the p53 signaling pathway [cyclin E2 (CCNE2), ribonucleotide reductase M2 subunit (RRM2)] and nitrogen metabolism [carbonic anhydrase 2 (CA2)], which were also included in the pathways of the CTD.	Nitrogen	184-192	tumor protein p53	Homo sapiens	94-97
31657122-3	2019	In this work, earth-abundant iron pyrite (FeS2 ) nanocrystals grown on carbon fiber paper (FeS2 /CFP) are found to be an electrochemical and photoactive catalyst for nitrogen reduction reaction under ambient temperature and pressure.	Nitrogen	166-174	complement factor properdin	Homo sapiens	97-100
31587407-5	2019	In this study, we present the first near-complete 15 N, 13 Calpha/beta , and HN backbone resonance assignments of two dimers of the dimerization domain (DD) of the NFkappaB1 (p50) protein (residues 241-351): the homodimer of two p50 domains and a heterodimer of the p50 DD with the p65 DD.	Nitrogen	53-54	nuclear factor kappa B subunit 1	Homo sapiens	175-178
31799876-6	2019	Blood urea nitrogen (BUN) and creatinine were higher in UCP2-/-+IR mouse serum than in IR mouse serum.	Nitrogen	11-19	uncoupling protein 2 (mitochondrial, proton carrier)	Mus musculus	56-60
31774106-0	2019	Blue fluorescence from N,O-coordinated BF2 complexes having aromatic chromophores in solution and the solid state.	Nitrogen	23-24	forkhead box G1	Homo sapiens	39-42
31600726-2	2019	N-linked glycans are co-translationally attached to the Asn7 and Asn24 residues on the FSHbeta subunit.	Nitrogen	0-1	follicle stimulating hormone beta	Mus musculus	87-94
31600726-3	2019	Differences in the number of N-glycans on the FSHbeta subunit result in distinct glycoforms: hypo-glycosylated (FSH21/18, glycans on either Asn24 or Asn7, respectively) or fully-glycosylated (FSH24, glycans on both Asn7 and Asn24).	Nitrogen	29-30	follicle stimulating hormone beta	Mus musculus	46-53
31801293-7	2019	For the first time, we hypothesize that the free thiol of monomeric xP1-and probably also its mammalian ortholog TFF1-could have a protective scavenger function, e.g., for reactive oxygen/nitrogen species.	Nitrogen	188-196	XPA, DNA damage recognition and repair factor	Homo sapiens	68-71
31801293-7	2019	For the first time, we hypothesize that the free thiol of monomeric xP1-and probably also its mammalian ortholog TFF1-could have a protective scavenger function, e.g., for reactive oxygen/nitrogen species.	Nitrogen	188-196	trefoil factor 1	Homo sapiens	113-117
31729498-2	2019	Without additives or ligands, the Pd(PPh3)4-catalyzed transformations undergo decarboxylative O- and N-heteroannulation processes to efficiently furnish structurally diverse [60]fullerene-fused heterocyclic derivatives.	Nitrogen	101-102	caveolin 1	Homo sapiens	37-41
32029032-1	2019	OBJECTIVE: To investigate whether endogenous nociceptin/orphanin FQ (N/OFQ) can inhibit arrhythmia and expression of beta1-adrenergic receptor (beta1-AR) on the surface of myocardial cell membrane in acute myocardial ischemia rats by Raf kinase inhibitory protein (RKIP).	Nitrogen	69-70	adrenoceptor beta 1	Rattus norvegicus	117-142
31683196-5	2019	The interacting domains between TRIM59 and nsp11 were further determined to be the N-terminal RING domain in TRIM59 and the C-terminal NendoU domain in nsp11, respectively.	Nitrogen	83-84	tripartite motif containing 59	Homo sapiens	32-38
31519237-0	2019	Ratiometric fluorescence strategy for p53 gene assay by using nitrogen doped graphene quantum dots and berberine as fluorescence reporters.	Nitrogen	62-70	tumor protein p53	Homo sapiens	38-41
31683196-5	2019	The interacting domains between TRIM59 and nsp11 were further determined to be the N-terminal RING domain in TRIM59 and the C-terminal NendoU domain in nsp11, respectively.	Nitrogen	83-84	tripartite motif containing 59	Homo sapiens	109-115
31828042-4	2019	Exploratory in silico analysis aided by phospho-substrate antibodies and ZEB1 deletion mutants led us to identify several potential phospho-sites for the family of PKC kinases in the N-terminus of ZEB1.	Nitrogen	183-184	protein kinase C alpha	Homo sapiens	164-167
31779172-4	2019	Each bacterium may use different receptors which recognize specific fibronectin domains, mostly the N-terminal domain and the central cell-binding domain.	Nitrogen	100-101	fibronectin 1	Homo sapiens	68-79
31519237-2	2019	Nitrogen doped graphene quantum dots (NGQDs) were firstly bound with a single-stranded DNA (P1 DNA), which contains berberine aptamer sequence and p53 gene complementary sequence (Cp53 DNA).	Nitrogen	0-8	tumor protein p53	Homo sapiens	147-150
31652301-6	2019	Here we have used different approaches to show that this event is accompanied by a specific change in the HDM2 structure that affects the HDM2 interactome, such as the N-termini HDM2 - p53 protein-protein interaction.	Nitrogen	168-169	tumor protein p53	Homo sapiens	185-188
31628192-3	2019	Here, we found that the N-terminal domain (NTD) of glutamate receptor ionotropic kainate 2 (GluK2) binds complement C1r/C1s-Uegf-BMP (CUB1) domains of Neto proteins (i.e. NTD-CUB1 interaction), and that the core of GluK2 (GluK2DeltaNTD) binds Netos through domains other than CUB1s (core-Neto interaction).	Nitrogen	24-25	complement C1r	Homo sapiens	105-119
31748248-8	2019	Yap1 lacks an N-terminal cysteine-rich domain (n-CRD), which is present in other fungal Yap1 orthologs, but has a C-terminal cysteine-rich domain (c-CRD).	Nitrogen	14-15	DNA-binding transcription factor YAP1	Saccharomyces cerevisiae S288C	0-4
31647066-4	2019	We demonstrated the superiority of our method by successfully enriching protein N-termini from as low as 10 ng of bovine serum albumin.	Nitrogen	80-81	albumin	Homo sapiens	121-134
31674777-1	2019	N-(2-Hydroxyethyl)ethylenediamine-N,N",N"-triacetic acid (HEDTA, denoted as H3L) is a strong chelating ligand that is widely used in the separation of f elements as relevant to the nuclear fuel cycle.	Nitrogen	0-56	H3 clustered histone 2	Homo sapiens	76-79
31674777-1	2019	N-(2-Hydroxyethyl)ethylenediamine-N,N",N"-triacetic acid (HEDTA, denoted as H3L) is a strong chelating ligand that is widely used in the separation of f elements as relevant to the nuclear fuel cycle.	Nitrogen	58-63	H3 clustered histone 2	Homo sapiens	76-79
31554661-0	2019	Mitochondrial amidoxime-reducing component 2 (mARC2) has a significant role in N-reductive activity and energy metabolism.	Nitrogen	79-80	mitochondrial amidoxime reducing component 2	Mus musculus	0-44
31554661-0	2019	Mitochondrial amidoxime-reducing component 2 (mARC2) has a significant role in N-reductive activity and energy metabolism.	Nitrogen	79-80	mitochondrial amidoxime reducing component 2	Mus musculus	46-51
31554661-6	2019	The MARC2-KO significantly decreased reductase activity toward several N-oxygenated substrates, and for typical mARC substrates, only a small residual reductive activity was still detectable in the MARC2-KO mice.	Nitrogen	71-72	mitochondrial amidoxime reducing component 2	Mus musculus	4-9
31554661-8	2019	These results clearly indicate that mARC2 is mainly responsible for N-reductive biotransformation in mice.	Nitrogen	68-69	mitochondrial amidoxime reducing component 2	Mus musculus	36-41
31744088-3	2019	In this study, we synthesized novel FXR agonists 1-4 possessing isoxazole and N-substituted benzimidazole moieties, and compared their effects on osteoblast differentiation with the known FXR agonists, chenodeoxycholic acid and a synthetic compound, GW4064.	Nitrogen	78-79	nuclear receptor subfamily 1, group H, member 4	Mus musculus	36-39
31727983-7	2019	Mass spectrometry analysis revealed that N-glycosylation of the produced EPO was similar to endogenous human proteins and non-human glycan epitopes were not detected.	Nitrogen	41-42	erythropoietin	Homo sapiens	73-76
31730008-0	2019	GPR110 (ADGRF1) mediates anti-inflammatory effects of N-docosahexaenoylethanolamine.	Nitrogen	54-83	adhesion G protein-coupled receptor F1	Mus musculus	0-6
31730008-0	2019	GPR110 (ADGRF1) mediates anti-inflammatory effects of N-docosahexaenoylethanolamine.	Nitrogen	54-83	adhesion G protein-coupled receptor F1	Mus musculus	8-14
31730008-16	2019	These effects were abolished by blocking synaptamide binding to GPR110 using an N-terminal targeting antibody.	Nitrogen	80-81	adhesion G protein-coupled receptor F1	Mus musculus	64-70
31723221-2	2019	Previous protein over-expression studies have shown that various mutations to the common N-terminal STAT1-binding motif of the NiV P, V, and W proteins affected the STAT1-binding ability of these proteins thus interfering with he JAK/STAT pathway and reducing their ability to inhibit type-I IFN signaling, but due to differing techniques it was unclear which amino acids were most important in this interaction or what impact this had on pathogenesis in vivo.	Nitrogen	89-90	signal transducer and activator of transcription 1-alpha/beta	Mustela putorius furo	100-105
31511384-14	2019	The two specific thioredoxin subunits of STT3B-OST MAGT1 and TUSC3 were found to be essential for the N-glycosylation of viral GP.	Nitrogen	102-103	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	47-50
31723221-2	2019	Previous protein over-expression studies have shown that various mutations to the common N-terminal STAT1-binding motif of the NiV P, V, and W proteins affected the STAT1-binding ability of these proteins thus interfering with he JAK/STAT pathway and reducing their ability to inhibit type-I IFN signaling, but due to differing techniques it was unclear which amino acids were most important in this interaction or what impact this had on pathogenesis in vivo.	Nitrogen	89-90	signal transducer and activator of transcription 1-alpha/beta	Mustela putorius furo	165-170
31717351-7	2019	The modulation of signaling and transcription factors, such as NIGTs, NFYA and CIPK23 might indicate that there is a complex network operating to maintain the expression of N-responsive genes, such as NRT2.1, NIA1 and NIR.	Nitrogen	63-64	nitrate reductase 1	Arabidopsis thaliana	209-213
31613097-5	2019	Here, we have envisaged that the inherent conformational dynamics of CaM is primarily triggered by a dual salt bridge interaction between the glutamates and lysine at two different domains (N and C terminal domains) of the protein.	Nitrogen	190-191	calmodulin 1	Homo sapiens	69-72
31466145-2	2019	Coupled system showed the highest total nitrogen (TN) removal efficiency of 67.85% with the addition of 15 g L-1 iron shavings at pH 7.0, which was higher than 29.62% in the mono-ZVI system and 43.86% in the mono-cell system.	Nitrogen	40-48	L1 cell adhesion molecule	Homo sapiens	109-112
31589421-2	2019	A diverse array of unsubstituted N-heteroarenes including pyridine, pyrrole and pyrazine, traditionally challenging substrates for hydrogenation, were successfully hydrogenated using the organometallic precatalysts, (eta5-C5Me5)Rh(N-C)H (N-C = 2-phenylpyridinyl (ppy) or benzo[h]quinolinyl (bq)).	Nitrogen	33-47	Sp2 transcription factor	Homo sapiens	240-242
31781322-8	2019	miR-200a supplementation blocked whole-body wasting and heart atrophy caused by acute DOX injection, decreased the levels of cardiac troponin I and the N-terminal probrain natriuretic peptide, and improved cardiac and adult cardiomyocyte contractile function.	Nitrogen	152-153	microRNA 200a	Rattus norvegicus	0-8
31542886-6	2019	SSPs moderate these N-load changes with small changes for SSP1 to large increases for SSP5, with greater increases for Norsminde than Kocinka due to land use differences.	Nitrogen	20-21	SUMO specific peptidase 6	Homo sapiens	58-62
31511323-0	2019	N-glycosylation of the voltage-gated sodium channel beta2 subunit is required for efficient trafficking of NaV1.5/beta2 to the plasma membrane.	Nitrogen	0-1	sodium voltage-gated channel alpha subunit 5	Canis lupus familiaris	107-113
31511323-11	2019	In conclusion, our results indicate that N-linked glycosylation of beta2 is required for surface localization of NaV1.5, a property that is often defective in inherited cardiac arrhythmias.	Nitrogen	41-42	sodium voltage-gated channel alpha subunit 5	Canis lupus familiaris	113-119
30724386-1	2019	The urea cycle and glutamine synthetase (GS) are the two main pathways for waste nitrogen removal and their deficiency results in hyperammonemia.	Nitrogen	81-89	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	19-39
31742248-4	2019	Through the production of an N-terminal polypeptide of HDAC4 (HDAC4-NT), ABHD5 inhibits MEF2-dependent gene expression and thereby controls glucose handling.	Nitrogen	29-30	histone deacetylase 4	Mus musculus	55-60
31742248-4	2019	Through the production of an N-terminal polypeptide of HDAC4 (HDAC4-NT), ABHD5 inhibits MEF2-dependent gene expression and thereby controls glucose handling.	Nitrogen	29-30	histone deacetylase 4	Mus musculus	62-70
31742248-4	2019	Through the production of an N-terminal polypeptide of HDAC4 (HDAC4-NT), ABHD5 inhibits MEF2-dependent gene expression and thereby controls glucose handling.	Nitrogen	29-30	myocyte enhancer factor 2C	Mus musculus	88-92
31358210-0	2019	Three-dimensional nitrogen-doped mesoporous carbon nanomaterials derived from plant biomass: Cost-effective construction of label-free electrochemical aptasensor for sensitively detecting alpha-fetoprotein.	Nitrogen	18-26	alpha fetoprotein	Homo sapiens	188-205
31357360-0	2019	Nitrogen doped carbon dots for turn-off fluorescent detection of alkaline phosphatase activity based on inner filter effect.	Nitrogen	0-8	alkaline phosphatase, placental	Homo sapiens	65-85
31357360-3	2019	In this work, a fluorescence turn-off approach for the detection of ALP is designed on the basis of nitrogen doped carbon dots (N-CDs), which were synthesized by one-step hydrothermal method and applied as signal readout.	Nitrogen	100-108	alkaline phosphatase, placental	Homo sapiens	68-71
31665640-5	2019	GLUL-deficient PDAC cells are capable of the TCA cycle but defective in aKG-coupled glutamine biosynthesis and subsequent nitrogen anabolic processes.	Nitrogen	122-130	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	0-4
31568752-6	2019	Using a series of spectroscopic assays and biochemical tests, we establish that QBP1 binds and inhibits amyloid formation by TDP-43"s Q/N-rich region.	Nitrogen	136-137	TAR DNA binding protein	Homo sapiens	125-131
31661786-1	2019	Soil nitrate-nitrogen (NO3--N) is one of the primary factors used to control nitrogen topdressing application during the crop growth period.	Nitrogen	13-21	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
31622882-2	2019	Here, we dissected the signals controlling phosphorylation and activity of the TORC1-effector kinase Npr1, involved in tuning the plasma membrane permeability to nitrogen sources.	Nitrogen	162-170	natriuretic peptide receptor 1	Homo sapiens	101-105
31622882-3	2019	By evaluating a role of pH as a signal, we show that, although a transient cytosolic acidification accompanies nitrogen source entry and is correlated to a rapid TORC1-dependent phosphorylation of Npr1, a pH drop is not a prerequisite for TORC1 activation.	Nitrogen	111-119	natriuretic peptide receptor 1	Homo sapiens	197-201
31622882-5	2019	Finally, our data reveal that Npr1 mediates nitrogen-dependent phosphorylation of Pib2, as well as a Pib2-dependent inhibition of TORC1.	Nitrogen	44-52	natriuretic peptide receptor 1	Homo sapiens	30-34
31844685-7	2019	Interestingly, the disordered C- and N- terminal regions of GEMININ were involved in binding to SIX3/SIX6.	Nitrogen	37-38	SIX homeobox 3	Homo sapiens	96-100
31471319-8	2019	ZNT1 is N-glycosylated on Asn 299 in the extracellular loop between transmembrane domains V and VI, and this appears to be involved in the regulation of ZNT1 stability, as nonglycosylated ZNT1 is more stable.	Nitrogen	1-2	solute carrier family 30 member 1	Homo sapiens	153-157
31471319-8	2019	ZNT1 is N-glycosylated on Asn 299 in the extracellular loop between transmembrane domains V and VI, and this appears to be involved in the regulation of ZNT1 stability, as nonglycosylated ZNT1 is more stable.	Nitrogen	1-2	solute carrier family 30 member 1	Homo sapiens	153-157
31573804-1	2019	Coordination complexes have emerged as prominent modulators of amyloid aggregation via their interaction with the N-terminal histidine residues of amyloid-beta (Abeta).	Nitrogen	114-115	amyloid beta precursor protein	Homo sapiens	161-166
31665640-8	2019	Therefore, GLUL-mediated glutamine biosynthesis couples the TCA cycle with nitrogen anabolism and plays a critical role in PDAC.	Nitrogen	75-83	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	11-15
31695625-6	2019	Using coimmunoprecipitation, we confirmed the physical interaction between ITM2B or TMEM85 and N-terminal GLUT9 isoforms (GLUT9a and GLUT9b) in transfected HEK 293T cells and Xenopus oocytes, wherein ITM2B but not TMEM85 inhibited GLUT9-mediated urate uptake.	Nitrogen	95-96	solute carrier family 2 member 9	Homo sapiens	106-111
31695426-9	2019	Overexpression of S100A11 also significantly downregulated E-caherin, and upregulated N-caherin, beta-catenin, and c-Myc in C33A cells (P &lt; 0.05).	Nitrogen	86-95	S100 calcium binding protein A11	Homo sapiens	18-25
31695625-6	2019	Using coimmunoprecipitation, we confirmed the physical interaction between ITM2B or TMEM85 and N-terminal GLUT9 isoforms (GLUT9a and GLUT9b) in transfected HEK 293T cells and Xenopus oocytes, wherein ITM2B but not TMEM85 inhibited GLUT9-mediated urate uptake.	Nitrogen	95-96	solute carrier family 2 (facilitated glucose transporter), member 9 L homeolog	Xenopus laevis	122-127
31695625-7	2019	Additionally, co-expression of ITM2B with GLUT9 in oocytes inhibited N-glycosylation of GLUT9a more than GLUT9b and stimulated urate efflux by both isoforms.	Nitrogen	69-70	solute carrier family 2 member 9	Homo sapiens	42-47
31628372-4	2019	Biomass concentration was enhanced to 4.1 g L-1 through intermittent feeding of nitrogen source and phosphate.	Nitrogen	80-88	immunoglobulin kappa variable 1-16	Homo sapiens	44-47
31586028-3	2019	4 lysine residues (K38KKK) located in the N-terminal domain of caspase-7 form such an exosite and promote the rapid proteolysis of the poly(ADP-ribose) polymerase 1 (PARP-1), but the mechanism of recognition remains mostly unknown.	Nitrogen	42-43	poly(ADP-ribose) polymerase 1	Homo sapiens	135-164
31586028-3	2019	4 lysine residues (K38KKK) located in the N-terminal domain of caspase-7 form such an exosite and promote the rapid proteolysis of the poly(ADP-ribose) polymerase 1 (PARP-1), but the mechanism of recognition remains mostly unknown.	Nitrogen	42-43	poly(ADP-ribose) polymerase 1	Homo sapiens	166-172
31637521-1	2019	A glassy carbon electrode (GCE) was coated with N-doped carbon-modified palygorskite and used as an electrochemical sensor for determination of Pb(II) by differential pulse anodic stripping voltammetry.	Nitrogen	48-49	submaxillary gland androgen regulated protein 3B	Homo sapiens	144-150
31635148-0	2019	N-Glycosylation of TREK-1/hK2P2.1 Two-Pore-Domain Potassium (K2P) Channels.	Nitrogen	0-1	potassium two pore domain channel subfamily K member 2	Homo sapiens	19-25
31635148-4	2019	This study aimed to evaluate whether hTREK-1 channels are N-glycosylated and whether glycosylation may affect channel functionality.	Nitrogen	58-59	potassium two pore domain channel subfamily K member 2	Homo sapiens	37-44
31635148-7	2019	TREK-1 channel subunits undergo N-glycosylation at asparagine residues 110 and 134.	Nitrogen	32-33	potassium two pore domain channel subfamily K member 2	Homo sapiens	0-6
31681252-5	2019	Specifically, surface layer protein (SLP) of LH2171 stimulated hBD2 expression by activating c-Jun N-terminal kinase (JNK) signaling via Toll-like receptor (TLR)2 in Caco-2 cells.	Nitrogen	99-100	defensin beta 4A	Homo sapiens	63-67
31681252-5	2019	Specifically, surface layer protein (SLP) of LH2171 stimulated hBD2 expression by activating c-Jun N-terminal kinase (JNK) signaling via Toll-like receptor (TLR)2 in Caco-2 cells.	Nitrogen	99-100	mitogen-activated protein kinase 8	Homo sapiens	118-121
31635263-4	2019	The ELP-VEGF fusion protein was modified by adding a kidney-targeting peptide (KTP) to the N-terminus.	Nitrogen	91-92	vascular endothelial growth factor A	Homo sapiens	8-12
31444841-4	2019	Through tuning both composition and pores, the 3D N-doped nanocarbon with a high sp3 /sp2 carbon ratio on the surface exhibits a superior electrocatalytic performance for the ORR compared to that of the commercial Pt/C in Zn-air batteries.	Nitrogen	50-51	Sp3 transcription factor	Homo sapiens	81-84
31323502-1	2019	This study investigated the feasibility of a new biological nitrogen removal process that integrates sulfur-driven autotrophic denitratation (NO3- NO2-) and anaerobic ammonium oxidation (Anammox) for simultaneous removal of nitrate and ammonium from industrial wastewater.	Nitrogen	60-68	NBL1, DAN family BMP antagonist	Homo sapiens	142-145
31571482-5	2019	Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph).	Nitrogen	116-124	Sp2 transcription factor	Homo sapiens	288-291
31571482-5	2019	Such Ln2@C80 molecules are unstable in the neutral form but can be stabilized by substitution of one carbon atom by nitrogen to give azafullerenes Ln2@C79N or by quenching the unpaired electron on the fullerene cage by reacting it with a chemical such as benzyl bromide, transforming one sp2 carbon into an sp3 carbon and yielding the monoadduct Ln2@C80(CH2Ph).	Nitrogen	116-124	Sp3 transcription factor	Homo sapiens	307-310
31542223-4	2019	The FLNA-MVD-causing mutations are clustered in the N-terminal region of FLNA.	Nitrogen	6-7	filamin A	Homo sapiens	73-77
31618999-4	2019	Three independent methods were applied in aggregation studies of the complexes of insulin with its N-methylated peptides.	Nitrogen	99-100	insulin	Homo sapiens	82-89
31618999-6	2019	Of the seven N-methylated analogs of the A- and B-chain hot-spots of insulin, six inhibited insulin aggregation (peptides 1 and 3-7).	Nitrogen	13-14	insulin	Homo sapiens	69-76
31444841-4	2019	Through tuning both composition and pores, the 3D N-doped nanocarbon with a high sp3 /sp2 carbon ratio on the surface exhibits a superior electrocatalytic performance for the ORR compared to that of the commercial Pt/C in Zn-air batteries.	Nitrogen	50-51	Sp2 transcription factor	Homo sapiens	86-89
31553183-0	2019	Correction to Discovery of 3-Oxabicyclo[4.1.0]heptane, a Non-nitrogen Containing Morpholine Isostere, and Its Application in Novel Inhibitors of the PI3K-AKT-mTOR Pathway.	Nitrogen	61-69	mechanistic target of rapamycin kinase	Homo sapiens	158-162
31549126-2	2019	Mechanistically, the formation of the title compounds is triggered by a Rh(iii)-catalyzed C(sp2)-H alkenylation of 1 with 2 followed by an intramolecular N-nucleophilic substitution.	Nitrogen	154-155	Sp2 transcription factor	Homo sapiens	90-95
31649511-3	2019	We show that shedding of the TREM2 N-terminal domain does not affect the inhibition of NFkappaB activation induced by TREM2 while it completely blocks phagocytosis suggesting that TREM2 anti-inflammatory properties can be mediated by the TREM2 C-terminal fragment while the phagocytic activity requires the full-length receptor.	Nitrogen	35-36	triggering receptor expressed on myeloid cells 2	Homo sapiens	29-34
31597105-3	2019	By characterizing SENP6, we define an N-terminal multi-SIM domain as a critical determinant in targeting SENP6 to SUMO chains.	Nitrogen	20-21	SUMO specific peptidase 6	Homo sapiens	105-110
31532667-0	2019	One-Step Facile Synthesis of Nitrogen-Doped Carbon Dots: A Ratiometric Fluorescent Probe for Evaluation of Acetylcholinesterase Activity and Detection of Organophosphorus Pesticides in Tap Water and Food.	Nitrogen	29-37	acetylcholinesterase (Cartwright blood group)	Homo sapiens	107-127
31532667-2	2019	In this study, a highly selective and sensitive ratiometric fluorescent probe was innovatively fabricated for the evaluation of AChE activity and the determination of OPs in tap water and food on the basis of the inner filter effect (IFE) between nitrogen-doped carbon dots (N-CDs) and 2,3-diaminophenazine (DAP).	Nitrogen	247-255	acetylcholinesterase (Cartwright blood group)	Homo sapiens	128-132
31412503-2	2019	Atmospheric deposition of N has been rapidly increasing since the industrial revolution, associated with fast compositional shifts between ammonium- (NH4+) and nitrate-N (NO3-) globally.	Nitrogen	26-27	NBL1, DAN family BMP antagonist	Homo sapiens	171-174
31631975-10	2019	Blood urea nitrogen was found to be a protective factor for TSP-1, while glucose and heart rate were found to be risk factors prior to and after treatment.	Nitrogen	11-19	thrombospondin 1	Homo sapiens	60-65
31589603-5	2019	BMP signalling appears to regulate ecdysone receptor (EcR) levels via one or more mechanisms involving the EcR"s N terminus or the RNA sequence that encodes it.	Nitrogen	113-114	Ecdysone receptor	Drosophila melanogaster	35-52
31854825-7	2019	The total amounts of nitrogen removed by synchronous nitrification and denitrification were 29.89, 28.77, and 29.78 mg L-1.	Nitrogen	21-29	L1 cell adhesion molecule	Homo sapiens	119-122
31589603-5	2019	BMP signalling appears to regulate ecdysone receptor (EcR) levels via one or more mechanisms involving the EcR"s N terminus or the RNA sequence that encodes it.	Nitrogen	113-114	Ecdysone receptor	Drosophila melanogaster	54-57
31589603-5	2019	BMP signalling appears to regulate ecdysone receptor (EcR) levels via one or more mechanisms involving the EcR"s N terminus or the RNA sequence that encodes it.	Nitrogen	113-114	Ecdysone receptor	Drosophila melanogaster	107-110
31545024-11	2019	NiL3S(OH2) is thus the first low-molecular weight, synthetic, bioinspired Ni complex that displays catalytic SOD activity in water at physiological pH, although it does not contain any N-donor ligand in its first coordination sphere, as in the NiSOD.	Nitrogen	0-1	superoxide dismutase 1	Homo sapiens	109-112
30935958-9	2019	In vivo PrP is N-glycosylated at positions Asn181 and Asn197.	Nitrogen	15-16	prion protein	Homo sapiens	8-11
31586052-5	2019	ProTiler also reveals unannotated essential domains, including the N-terminus of the SWI/SNF subunit SMARCB1, which is validated experimentally.	Nitrogen	67-68	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	Homo sapiens	101-108
31589148-6	2019	Two L5 ligands are bound to two Ag1 centres through two oxadiazole N and two pyridyl N atoms to form a macrocycle.	Nitrogen	67-68	NBPF member 10	Homo sapiens	32-35
31152903-9	2019	Based on this, the content variation of TN, NH4+-N and NO3--N could be analyzed by a system-wide and established the nitrogen balance model, which provides a new insight into the enhancement of nitrogen removal in the bioretention system.	Nitrogen	117-125	NBL1, DAN family BMP antagonist	Homo sapiens	55-58
31152903-9	2019	Based on this, the content variation of TN, NH4+-N and NO3--N could be analyzed by a system-wide and established the nitrogen balance model, which provides a new insight into the enhancement of nitrogen removal in the bioretention system.	Nitrogen	194-202	NBL1, DAN family BMP antagonist	Homo sapiens	55-58
31299492-3	2019	Derivatives bearing a long alkyl chain at the nitrogen atom of the quinolone ring and having a suitable substituent at the 7-position of quinolone exhibited potent RyR1 channel-inhibitory activity.	Nitrogen	46-54	ryanodine receptor 1	Homo sapiens	164-168
31494090-5	2019	The hiPSCs were frozen as aggregates by using a programmable freezer and then stored in liquid nitrogen at -196  C. It was seen that catalase improved the revival efficiency by reducing the late apoptotic populations and increasing the live cell fraction.	Nitrogen	95-103	catalase	Homo sapiens	133-141
31330348-10	2019	Considering the higher concentrations of NH4+ and higher ratio of NH4+/NO3- measured in fog than in rain, we suggest that quantification of fog nitrogen deposition and its ecological effect in this area should be given more attention.	Nitrogen	144-152	zinc finger protein, FOG family member 1	Homo sapiens	88-91
31330348-10	2019	Considering the higher concentrations of NH4+ and higher ratio of NH4+/NO3- measured in fog than in rain, we suggest that quantification of fog nitrogen deposition and its ecological effect in this area should be given more attention.	Nitrogen	144-152	zinc finger protein, FOG family member 1	Homo sapiens	140-143
31336256-7	2019	Significant greater stability and enhanced nitrogen removal efficiency have been demonstrated in the novel integrations of PD and anammox process, indicating a broad perspective in dealing with the mainstream municipal sewage, ammonia-rich streams, and industrial NO3--N contained wastewater.	Nitrogen	43-51	NBL1, DAN family BMP antagonist	Homo sapiens	264-267
31548691-5	2019	Thus, Shh inactivates PTCH1 by grasping its extracellular domain with two lipidic pincers, the N-terminal palmitate and the C-terminal cholesterol, which are both inserted into the PTCH1 protein core.	Nitrogen	95-96	patched 1	Homo sapiens	22-27
31696472-9	2019	Inhibition of lncRNA AOC4P expression also can result in the decreased expression levels of extracellular-signal-regulated kinase 1 (ERK1), c-Jun N-terminal kinases (JNK) and p38 proteins.	Nitrogen	18-19	mitogen-activated protein kinase 3	Homo sapiens	92-131
31696472-9	2019	Inhibition of lncRNA AOC4P expression also can result in the decreased expression levels of extracellular-signal-regulated kinase 1 (ERK1), c-Jun N-terminal kinases (JNK) and p38 proteins.	Nitrogen	18-19	mitogen-activated protein kinase 3	Homo sapiens	133-137
31696472-9	2019	Inhibition of lncRNA AOC4P expression also can result in the decreased expression levels of extracellular-signal-regulated kinase 1 (ERK1), c-Jun N-terminal kinases (JNK) and p38 proteins.	Nitrogen	18-19	mitogen-activated protein kinase 1	Homo sapiens	175-178
31368004-2	2019	Profound analyte oxidation was observed for particular compounds (TNT (9) and 2, 4-DNT (10)), whose mass spectra were completely dominated by the oxidation products when nitrogen was substituted for helium in DART analysis.	Nitrogen	170-178	chromosome 16 open reading frame 82	Homo sapiens	66-69
31548691-5	2019	Thus, Shh inactivates PTCH1 by grasping its extracellular domain with two lipidic pincers, the N-terminal palmitate and the C-terminal cholesterol, which are both inserted into the PTCH1 protein core.	Nitrogen	95-96	patched 1	Homo sapiens	181-186
31755042-9	2019	We found that the toxicity of (UGGAA)n is length- and expression level-dependent, and it was dampened by co-expressing TDP-43, FUS, and hnRNP A2/B1.	Nitrogen	36-38	FUS RNA binding protein	Homo sapiens	127-130
31202607-5	2019	We found that removing putative N-glycosylation sites alters the functional properties of GluN1/GluN3B receptors, but has no effect on GluN1/GluN3A receptors.	Nitrogen	32-33	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	90-95
31755042-9	2019	We found that the toxicity of (UGGAA)n is length- and expression level-dependent, and it was dampened by co-expressing TDP-43, FUS, and hnRNP A2/B1.	Nitrogen	36-38	heterogeneous nuclear ribonucleoprotein A2/B1	Homo sapiens	136-147
31598285-3	2019	The river sediment was added into the reactor daily and the hydraulic retention time (HRT) of the reactor was gradually reduced from 8 to 4 h. The reactor achieved in the N O 3   -  N  removal efficiency of 85% with the N O 3   -  N  removal rate of 0.27 kg N m-3 d-1.	Nitrogen	171-172	NBL1, DAN family BMP antagonist	Homo sapiens	220-225
31254883-5	2019	In case of diphenylamine, for which most of the identified intermediates were available as standard, the relative significance of each transformation route could be established, highlighting for the first time the important role of N-nitrosation processes in UV/NO3- treatment followed by the decomposition of the resulting N-nitroso compounds by an alpha hydroxylation mechanism.	Nitrogen	232-233	NBL1, DAN family BMP antagonist	Homo sapiens	262-265
31260829-1	2019	Fertilized agroecosystems may show considerable leaching of the mobile nitrogen (N) compound NO3-, which pollutes groundwater and causes eutrophication of downstream waterbodies.	Nitrogen	71-79	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
31616837-6	2019	Particularly, the O2/N2 separation performance of the PIM-1/ZIF-8-7 composite membrane exceeds the Robeson upper bound line.	Nitrogen	21-23	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	54-59
31684623-5	2019	Nonvolatile digital information storage is enabled when the In2O3/PEDOT:PSS/quartz structure is encapsulated in nitrogen.	Nitrogen	112-120	PSS	Homo sapiens	72-75
31616837-0	2019	High Performance of PIM-1/ZIF-8 Composite Membranes for O2/N2 Separation.	Nitrogen	59-61	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	20-25
31616837-5	2019	The pure-gas permeation results confirmed that growth of ZIF-8 on the PIM-1 membrane can enhance the performance of O2/N2 separation.	Nitrogen	119-121	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	70-75
31173100-7	2019	By contrast, cep3-1 had an increased meristem size and S-phase cell number under nitrogen (N)-limited conditions, but not under N-sufficient conditions.	Nitrogen	81-89	Cysteine proteinases superfamily protein	Arabidopsis thaliana	13-17
31173100-7	2019	By contrast, cep3-1 had an increased meristem size and S-phase cell number under nitrogen (N)-limited conditions, but not under N-sufficient conditions.	Nitrogen	91-92	Cysteine proteinases superfamily protein	Arabidopsis thaliana	13-17
31598285-3	2019	The river sediment was added into the reactor daily and the hydraulic retention time (HRT) of the reactor was gradually reduced from 8 to 4 h. The reactor achieved in the N O 3   -  N  removal efficiency of 85% with the N O 3   -  N  removal rate of 0.27 kg N m-3 d-1.	Nitrogen	182-183	NBL1, DAN family BMP antagonist	Homo sapiens	171-176
31173100-8	2019	Furthermore, cep3-1 meristematic cells remained in S-phase longer than wild type cells during a sustained carbon (C)- and N-limitation.	Nitrogen	122-123	Cysteine proteinases superfamily protein	Arabidopsis thaliana	13-17
31598285-3	2019	The river sediment was added into the reactor daily and the hydraulic retention time (HRT) of the reactor was gradually reduced from 8 to 4 h. The reactor achieved in the N O 3   -  N  removal efficiency of 85% with the N O 3   -  N  removal rate of 0.27 kg N m-3 d-1.	Nitrogen	182-183	NBL1, DAN family BMP antagonist	Homo sapiens	220-225
31598285-3	2019	The river sediment was added into the reactor daily and the hydraulic retention time (HRT) of the reactor was gradually reduced from 8 to 4 h. The reactor achieved in the N O 3   -  N  removal efficiency of 85% with the N O 3   -  N  removal rate of 0.27 kg N m-3 d-1.	Nitrogen	182-183	NBL1, DAN family BMP antagonist	Homo sapiens	171-176
31598285-3	2019	The river sediment was added into the reactor daily and the hydraulic retention time (HRT) of the reactor was gradually reduced from 8 to 4 h. The reactor achieved in the N O 3   -  N  removal efficiency of 85% with the N O 3   -  N  removal rate of 0.27 kg N m-3 d-1.	Nitrogen	182-183	NBL1, DAN family BMP antagonist	Homo sapiens	220-225
31554244-6	2019	Finally, we present preliminary data showing that the cytokine IL-6 cross talks with activation of the c-Jun N-terminal kinase pathway in response to heme-hemopexin in models of hepatocytes.	Nitrogen	109-110	interleukin 6	Homo sapiens	63-67
31150877-4	2019	The results indicated that under long-term exposure to 5 mg L-1 tetracycline and 1 mg L-1 sulfamethoxazole, removals of chemical oxygen demand and total nitrogen were inhibited, the tendency of sludge bulking was increased, more filamentous bacteria were observed and more extracellular polymeric substance was secreted.	Nitrogen	153-161	immunoglobulin kappa variable 1-16	Homo sapiens	60-82
31549143-1	2019	N-carbamylglutamate (NCG), an analogue of N-acetyl-L-glutamate (NAG), can increase arginine synthesis in mammals and improve the reproductive performance.	Nitrogen	0-19	neuroblastoma amplified sequence	Gallus gallus	42-62
31549143-1	2019	N-carbamylglutamate (NCG), an analogue of N-acetyl-L-glutamate (NAG), can increase arginine synthesis in mammals and improve the reproductive performance.	Nitrogen	0-19	neuroblastoma amplified sequence	Gallus gallus	64-67
31549143-1	2019	N-carbamylglutamate (NCG), an analogue of N-acetyl-L-glutamate (NAG), can increase arginine synthesis in mammals and improve the reproductive performance.	Nitrogen	21-24	neuroblastoma amplified sequence	Gallus gallus	42-62
31549143-1	2019	N-carbamylglutamate (NCG), an analogue of N-acetyl-L-glutamate (NAG), can increase arginine synthesis in mammals and improve the reproductive performance.	Nitrogen	21-24	neuroblastoma amplified sequence	Gallus gallus	64-67
31546993-4	2019	In this work, using lung and breast cancer cell lines, we showed for the first time that the full-length HtrA4 and its N-terminally deleted variant promote cancer cell death induced by chemotherapeutic drugs by enhancing apoptosis.	Nitrogen	119-120	HtrA serine peptidase 4	Homo sapiens	105-110
31546993-5	2019	The effect is dependent on the HtrA4 proteolytic activity, and the N-terminally deleted HtrA4 is more efficient in the cell death stimulation.	Nitrogen	67-68	HtrA serine peptidase 4	Homo sapiens	88-93
31150877-4	2019	The results indicated that under long-term exposure to 5 mg L-1 tetracycline and 1 mg L-1 sulfamethoxazole, removals of chemical oxygen demand and total nitrogen were inhibited, the tendency of sludge bulking was increased, more filamentous bacteria were observed and more extracellular polymeric substance was secreted.	Nitrogen	153-161	immunoglobulin kappa variable 1-16	Homo sapiens	60-63
31475996-2	2019	By employing a FeCl3 and BF3 OEt2 co-catalytic strategy, the ring-opening of 1-tosyl-2,3-dihydro-1H-pyrroles by selective cleavage of the C(sp2)-N bond and subsequent annulation have been achieved to access 1-tosyl-2,3-dihydro-1H-azepines with excellent regioselectivity, offering a new avenue for cycloaddition through the ring-opening of non-strained-ring-based units.	Nitrogen	145-146	Sp2 transcription factor	Homo sapiens	138-143
31572984-7	2019	The Nrf2 activity of the compound NQC was determined using "Keap1:Nrf2 Inhibitor Screening Assay Kit".	Nitrogen	34-37	nuclear factor, erythroid derived 2, like 2	Mus musculus	4-8
31572984-7	2019	The Nrf2 activity of the compound NQC was determined using "Keap1:Nrf2 Inhibitor Screening Assay Kit".	Nitrogen	34-37	nuclear factor, erythroid derived 2, like 2	Mus musculus	66-70
31572984-8	2019	To obtain the insights on NQC"s activity on Nrf2, molecular docking studies were performed using Schrodinger suite.	Nitrogen	26-29	nuclear factor, erythroid derived 2, like 2	Mus musculus	44-48
31572984-12	2019	NQC dose-dependently down-regulated the pro-inflammatory cytokines [interleukin (IL)-1beta (13.27 +- 2.37 muM), IL-6 (10.13 +- 0.58 muM) and tumor necrosis factor (TNF)-alpha] (14.41 +- 1.83 muM); and inflammatory mediator, prostaglandin E2 (PGE2) with IC50 values, 15.23 +- 0.91 microM.	Nitrogen	0-3	interleukin 1 beta	Mus musculus	68-90
31572984-12	2019	NQC dose-dependently down-regulated the pro-inflammatory cytokines [interleukin (IL)-1beta (13.27 +- 2.37 muM), IL-6 (10.13 +- 0.58 muM) and tumor necrosis factor (TNF)-alpha] (14.41 +- 1.83 muM); and inflammatory mediator, prostaglandin E2 (PGE2) with IC50 values, 15.23 +- 0.91 microM.	Nitrogen	0-3	interleukin 6	Mus musculus	112-116
31572984-12	2019	NQC dose-dependently down-regulated the pro-inflammatory cytokines [interleukin (IL)-1beta (13.27 +- 2.37 muM), IL-6 (10.13 +- 0.58 muM) and tumor necrosis factor (TNF)-alpha] (14.41 +- 1.83 muM); and inflammatory mediator, prostaglandin E2 (PGE2) with IC50 values, 15.23 +- 0.91 microM.	Nitrogen	0-3	tumor necrosis factor	Mus musculus	141-174
31572984-17	2019	Conclusion: NQC is a new class of NRF2 activator with potent in vitro anti-inflammatory activity and good metabolic stability.	Nitrogen	12-15	nuclear factor, erythroid derived 2, like 2	Mus musculus	34-38
31548798-9	2019	None of the N- and C-terminally cleaved GIP peptides affected glucose homeostasis when injected alone with glucose.	Nitrogen	0-1	gastric inhibitory polypeptide	Mus musculus	40-43
31220676-1	2019	In an effort to develop novel Bax activators for breast cancer treatment, a series of diverse analogues have been designed and synthesized based on lead compound SMBA1 through several strategies, including introducing various alkylamino side chains to have a deeper access to S184 pocket, replacing carbon atoms with nitrogen, and reducing the nitro group of 9H-fluorene scaffold.	Nitrogen	317-325	BCL2 associated X, apoptosis regulator	Homo sapiens	30-33
31419131-3	2019	The accuracy was guaranteed by optimizing the repulsive potential between the sp3-hybridized nitrogen and hydrogen atoms in a SCC-DFTB3 parameter set for the system to reproduce high-level quantum chemical calculations.	Nitrogen	93-101	Sp3 transcription factor	Homo sapiens	78-81
31854866-2	2019	The results showed that the main forms of nitrogen-containing substances in the lower reaches of the Fenhe River are NO3--N and NH4+-N and that the NO3--N content in 77.8% of the samples exceed the national drinking water standard.	Nitrogen	42-50	NBL1, DAN family BMP antagonist	Homo sapiens	117-120
31367714-2	2019	Treatment of [Ru(OAc)2(CO)(PPh3)2] with NN ligands in methanol gives the cationic derivatives [Ru(OAc)(CO)(PPh3)(NN)]OAc (NN = en 4, ampy 5) in which one acetate acts as a bidentate ligand, whereas the other is not coordinated.	Nitrogen	40-42	caveolin 1	Homo sapiens	27-31
31367714-2	2019	Treatment of [Ru(OAc)2(CO)(PPh3)2] with NN ligands in methanol gives the cationic derivatives [Ru(OAc)(CO)(PPh3)(NN)]OAc (NN = en 4, ampy 5) in which one acetate acts as a bidentate ligand, whereas the other is not coordinated.	Nitrogen	40-42	caveolin 1	Homo sapiens	107-111
31367714-2	2019	Treatment of [Ru(OAc)2(CO)(PPh3)2] with NN ligands in methanol gives the cationic derivatives [Ru(OAc)(CO)(PPh3)(NN)]OAc (NN = en 4, ampy 5) in which one acetate acts as a bidentate ligand, whereas the other is not coordinated.	Nitrogen	113-115	caveolin 1	Homo sapiens	27-31
31367714-2	2019	Treatment of [Ru(OAc)2(CO)(PPh3)2] with NN ligands in methanol gives the cationic derivatives [Ru(OAc)(CO)(PPh3)(NN)]OAc (NN = en 4, ampy 5) in which one acetate acts as a bidentate ligand, whereas the other is not coordinated.	Nitrogen	113-115	caveolin 1	Homo sapiens	107-111
31854866-2	2019	The results showed that the main forms of nitrogen-containing substances in the lower reaches of the Fenhe River are NO3--N and NH4+-N and that the NO3--N content in 77.8% of the samples exceed the national drinking water standard.	Nitrogen	42-50	NBL1, DAN family BMP antagonist	Homo sapiens	148-151
31552043-3	2019	Here, we report crystal structures of monomerized properdin, which was produced by co-expression of separate N- and C-terminal constructs that yielded monomer-sized properdin complexes that stabilized C3bBb.	Nitrogen	109-110	complement factor properdin	Homo sapiens	50-59
31486941-7	2019	The oligosaccharide structures in the N-glycosylation patterns of the E2-CD154 protein produced by this cell line in 10 L fermenters with two different culture media were also analyzed.	Nitrogen	38-39	CD40 ligand	Homo sapiens	73-78
31552043-4	2019	Consistent with previous low-resolution X-ray and EM data, the crystal structures revealed ring-shaped arrangements that are formed by interactions between thrombospondin type-I repeat (TSR) domains 4 and 6 of one protomer interacting with the N-terminal domain (which adopts a short transforming-growth factor B binding protein-like fold) and domain TSR1 of a second protomer, respectively.	Nitrogen	244-245	TSR1 ribosome maturation factor	Homo sapiens	351-355
31400547-8	2019	The OCN levels were correlated with the eGFR (p = 0.002), tooth loss (p = 0.023), blood urea nitrogen (p = 0.040), and creatinine levels (p = 0.031).	Nitrogen	93-101	bone gamma-carboxyglutamate protein	Homo sapiens	4-7
31301837-9	2019	Milk urea nitrogen was least in cows fed CM with 27% starch compared with the other 3 diets.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
31339777-5	2019	ANG II induced similar elevations of systolic blood pressure in Trpa1-/- and wild-type (WT) mice but led to higher levels of blood urea nitrogen (P < 0.05), serum creatinine (P < 0.05), and renal fibrosis (P < 0.01) in Trpa1-/- mice than WT mice.	Nitrogen	136-144	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-6
31176936-3	2019	Significantly higher total nitrogen removal efficiency (TNRE) was observed in L1-CDBFT (92.2%) than C1-CDBFT (87.5%, P &lt; 0.05; after day 14).	Nitrogen	27-35	immunoglobulin kappa variable 1-16	Homo sapiens	78-86
31944034-1	2019	A new family of azaacenes has been designed and synthesized by incorporating the electron-withdrawing sp2 -hybridized nitrogen of pyrazine and electron-donating nitrogen of carbazole in a molecular skeleton.	Nitrogen	118-126	Sp2 transcription factor	Homo sapiens	102-105
30393914-11	2019	Parameters affecting PCPE-1 elevation in the patient group were identified as systolic blood pressure, blood urea nitrogen, phosphorus, haemoglobin, intact parathormone levels, glomerular filtration rate and body mass index.	Nitrogen	114-122	procollagen C-endopeptidase enhancer	Homo sapiens	21-27
31437742-9	2019	More inorganic N components (mainly NO3-) were found in young trees than in old trees.	Nitrogen	15-16	NBL1, DAN family BMP antagonist	Homo sapiens	36-39
31348670-1	2019	A straightforward method for the preparation of non-K region fused phosphorus- and nitrogen-containing (PN)-heterocyclic pyrenes has been accomplished.	Nitrogen	83-91	U6 snRNA biogenesis phosphodiesterase 1	Homo sapiens	104-106
31528805-1	2019	Highly selective removal of N2 from unconventional natural gas is considered as a viable way to increase the heat value of CH4 and reduce the greenhouse effect caused by the direct emission of CH4/N2 mixture.	Nitrogen	28-30	chimerin 2	Homo sapiens	193-199
31318369-1	2019	This study details the syntheses of N-heterocyclic germylenes and stannylenes featuring diazaborolyl groups, {(HCDippN)2B} (Dipp = 2,6-iPr2C6H3), as both of the N-bound substituents, with a view to generating electron rich and sterically protected metal centres.	Nitrogen	36-37	nudix hydrolase 4	Homo sapiens	124-132
31108360-7	2019	The results indicate that the total deposition of NO3- and NH4+ combined could contribute to ~2.4% and ~1.9% of the primary production in the coastal areas east of the Korean Peninsula and in the East Asian marginal seas, respectively, which would be a lower bound because the dry deposition of reactive nitrogen gas was not included.	Nitrogen	304-312	NBL1, DAN family BMP antagonist	Homo sapiens	50-53
31128398-2	2019	SEM, N2 adsorption/desorption isotherms, TGA and EDS spectroscopy characterization results showed that CA-MP and CA-BOPhen were successfully introduced into the pores of SiO2-P carrier via physical intermolecular interactions.	Nitrogen	5-7	cathelicidin antimicrobial peptide	Homo sapiens	103-108
31485275-7	2019	The expression of mTOR was correlated with serum creatinine, blood urea nitrogen, estimated glomerular filtration rate, 24 h proteinuria, and cystatin C.	Nitrogen	72-80	mechanistic target of rapamycin kinase	Homo sapiens	18-22
30980427-1	2019	RATIONALE: The nitrogen and oxygen (delta15 N, delta18 O, and delta17 O values) isotopic compositions of nitrate (NO3 - ) are crucial tracers of nutrient nitrogen (N) sources and dynamics in aquatic systems.	Nitrogen	15-23	NBL1, DAN family BMP antagonist	Homo sapiens	114-117
30980427-1	2019	RATIONALE: The nitrogen and oxygen (delta15 N, delta18 O, and delta17 O values) isotopic compositions of nitrate (NO3 - ) are crucial tracers of nutrient nitrogen (N) sources and dynamics in aquatic systems.	Nitrogen	154-162	NBL1, DAN family BMP antagonist	Homo sapiens	114-117
31582880-9	2019	According to our results, the N-terminal kinase domain of RIPK4 is responsible for KRT14-RIPK4 interaction; however, the RIPK4 kinase activity is dispensable for the interaction.	Nitrogen	30-31	receptor interacting serine/threonine kinase 4	Homo sapiens	58-63
31413343-3	2019	In this paper, a persistent-current superconducting magnets system with solid nitrogen (SN2) cooling preservation is proposed for liberation of its demanding on-board power feeding requirement.	Nitrogen	78-86	solute carrier family 38 member 5	Homo sapiens	88-91
30982513-3	2019	In the present work, for the first time, AFS is employed for sensitive monitoring of nitrogen nutrients, i.e., NO2-, NO3- and NH4+, with nitric oxide (NO) vapor generation.	Nitrogen	85-93	NBL1, DAN family BMP antagonist	Homo sapiens	117-120
31854767-4	2019	The results showed that the stabilized sludge dosage was 3%, and the annual average mass concentrations of total nitrogen (TN) and nitrate nitrogen (NO3--N) were 3.27 mg L-1 and 1.61 mg L-1.	Nitrogen	149-155	immunoglobulin kappa variable 1-16	Homo sapiens	170-179
31854767-7	2019	As a result, the concentrations of TN and NO3--N in the effluent were decreased to 2.16 mg L-1 and 1.38 mg L-1, respectively.	Nitrogen	42-48	immunoglobulin kappa variable 1-16	Homo sapiens	91-94
31854767-7	2019	As a result, the concentrations of TN and NO3--N in the effluent were decreased to 2.16 mg L-1 and 1.38 mg L-1, respectively.	Nitrogen	42-48	immunoglobulin kappa variable 1-16	Homo sapiens	107-110
31398794-7	2019	The qualitative analysis of degradation products confirmed the involvement of hydroxyl radical and sulfate radical and figured out that the active sites of ACE were the C=C bond, ether bond, and C-N bond.	Nitrogen	197-198	angiotensin I converting enzyme	Homo sapiens	156-159
31582880-9	2019	According to our results, the N-terminal kinase domain of RIPK4 is responsible for KRT14-RIPK4 interaction; however, the RIPK4 kinase activity is dispensable for the interaction.	Nitrogen	30-31	receptor interacting serine/threonine kinase 4	Homo sapiens	89-94
31582880-9	2019	According to our results, the N-terminal kinase domain of RIPK4 is responsible for KRT14-RIPK4 interaction; however, the RIPK4 kinase activity is dispensable for the interaction.	Nitrogen	30-31	receptor interacting serine/threonine kinase 4	Homo sapiens	89-94
31380790-0	2019	Two CoII coordination polymers of biphenyl-2,2",5,5"-tetracarboxylic acid with flexible N-donor ligands: syntheses, structures and magnetic properties.	Nitrogen	88-89	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
31299388-5	2019	Finally, our observations indicated that the down-regulation of cyclin E protein might be involved in the inhibitory effects of maternal n-3 PUFAs deficient diet on the proliferation of cortical NPCs.	Nitrogen	2-3	cyclin E1	Rattus norvegicus	64-72
30744339-5	2019	Milk protein content and nitrogen conversion were higher (p&lt;0.05), while milk urea nitrogen was lower (p&lt;0.01) for cows fed AH than CSM-fed cows.	Nitrogen	86-94	Weaning weight-maternal milk	Bos taurus	76-80
30973186-3	2019	EPO variants with an alkyne-bearing non-natural amino acid (Plk) at the N-glycosylation sites 24, 38, and 83 were obtained by amber suppression followed by protein purification and refolding.	Nitrogen	72-73	erythropoietin	Homo sapiens	0-3
31183756-1	2019	The electrochemical conversion of inorganic nitrogen forms (i.e., NO3--N, NO2--N, and NH4+-N) to N2 was studied using Ti as cathode and Ti/PbO2 as anode in the simulated wastewater.	Nitrogen	44-52	NBL1, DAN family BMP antagonist	Homo sapiens	66-69
31183756-4	2019	The apparent rate constants of NO3--N to NO2--N and NO2--N to N2 were 2.46 x 10-2 min-1 and 4.03 x 10-2 min-1, respectively.	Nitrogen	62-64	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
31183756-8	2019	The results verified the pathways of NH4+-N oxidation and NO3--N reduction and achieved high conversion rate of total nitrogen (TN) to N2.	Nitrogen	118-126	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
31183756-8	2019	The results verified the pathways of NH4+-N oxidation and NO3--N reduction and achieved high conversion rate of total nitrogen (TN) to N2.	Nitrogen	135-137	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
31292599-10	2019	CONCLUSION: Our meta-analysis found that low-ratio n-6/n-3 PUFA supplementation could improve the glucose metabolism by reducing the insulin and insulin resistance in the diabetic patients.	Nitrogen	22-23	insulin	Homo sapiens	133-140
31292599-10	2019	CONCLUSION: Our meta-analysis found that low-ratio n-6/n-3 PUFA supplementation could improve the glucose metabolism by reducing the insulin and insulin resistance in the diabetic patients.	Nitrogen	33-34	insulin	Homo sapiens	133-140
31292599-10	2019	CONCLUSION: Our meta-analysis found that low-ratio n-6/n-3 PUFA supplementation could improve the glucose metabolism by reducing the insulin and insulin resistance in the diabetic patients.	Nitrogen	33-34	insulin	Homo sapiens	145-152
31227868-5	2019	All nitrate produced by anammox bacteria (57 mg N-NO3- L-1 day-1) was consumed, leading to a nitrogen removal efficiency of 97.5%.	Nitrogen	93-101	L1 cell adhesion molecule	Homo sapiens	55-58
31175846-5	2019	We also review data showing that solvent deuterium oxide isotope effects for decarbamoylation decreased from 2.8 for N-monomethylcarbamoyl AChE to 1.1 for N,N-diethylcarbamoyl AChE, indicating a shift in the rate-limiting step from general acid-base catalysis to a likely conformational change in the distorted active site in N,N-diethylcarbamoyl AChE.	Nitrogen	117-118	acetylcholinesterase (Cartwright blood group)	Homo sapiens	139-143
31175846-5	2019	We also review data showing that solvent deuterium oxide isotope effects for decarbamoylation decreased from 2.8 for N-monomethylcarbamoyl AChE to 1.1 for N,N-diethylcarbamoyl AChE, indicating a shift in the rate-limiting step from general acid-base catalysis to a likely conformational change in the distorted active site in N,N-diethylcarbamoyl AChE.	Nitrogen	117-118	acetylcholinesterase (Cartwright blood group)	Homo sapiens	176-180
31175846-5	2019	We also review data showing that solvent deuterium oxide isotope effects for decarbamoylation decreased from 2.8 for N-monomethylcarbamoyl AChE to 1.1 for N,N-diethylcarbamoyl AChE, indicating a shift in the rate-limiting step from general acid-base catalysis to a likely conformational change in the distorted active site in N,N-diethylcarbamoyl AChE.	Nitrogen	117-118	acetylcholinesterase (Cartwright blood group)	Homo sapiens	176-180
30901737-3	2019	The P2X7 receptor is most involved in the activation of host microbicidal mechanisms, including production of reactive oxygen and nitrogen species, phagolysosomal fusion, acidification of parasitophorous vacuoles and release of cytokines and chemokines.	Nitrogen	130-138	purinergic receptor P2X 7	Homo sapiens	4-17
31307013-0	2019	N-Glycosylation influences human corticosteroid-binding globulin measurements.	Nitrogen	0-1	serpin family A member 6	Homo sapiens	33-64
31307013-6	2019	Qualitative differences in N-glycosylation at N238 also negatively affect the steroid-binding of CBG in the absence of an N-glycan at N347 caused by a T349A substitution.	Nitrogen	27-28	serpin family A member 6	Homo sapiens	97-100
31307013-9	2019	CONCLUSIONS: Plasma CBG measurements are influenced by variations in N-glycosylation.	Nitrogen	2-3	serpin family A member 6	Homo sapiens	20-23
31313790-5	2019	Exposure to As(iii) and As(v) generates an increase in the release of the pro-inflammatory cytokine IL-8 (57-1135%) and an increase in the generation of reactive oxygen and/or nitrogen species (130-340%) in both cell lines.	Nitrogen	176-184	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	24-29
31264321-2	2019	We recently reported that a synthetic N-terminally biotinylated peptide, BP21, alleviates hypothermia and vascular hyperpermeability during anaphylactic reactions in a mouse model of anaphylaxis via the direct binding of a Tyr-Lys-Asp-Gly sequence in the peptide to PAF.	Nitrogen	38-39	BP21	Homo sapiens	73-77
31332310-8	2019	SS120 has a different tactic to cope with low-light levels, and SS120 thylakoids contained hundreds of closely packed Pcb-PSI supercomplexes that economize on the extra iron and nitrogen required to assemble PSI-only domains.	Nitrogen	178-186	pyruvate carboxylase	Homo sapiens	118-121
31251477-3	2019	Here, we investigated the features of a rare SNP (F51S) of A1AT, which introduces an additional N-glycosylation site in the N-terminal region of A1AT.	Nitrogen	46-47	serpin family A member 1	Homo sapiens	59-63
31251477-3	2019	Here, we investigated the features of a rare SNP (F51S) of A1AT, which introduces an additional N-glycosylation site in the N-terminal region of A1AT.	Nitrogen	46-47	serpin family A member 1	Homo sapiens	145-149
31117816-11	2019	Given that LDL-C was also reduced in a group of clinically unaffected heterozygotes, we propose that increasing LDL receptor-mediated cholesterol clearance by targeting N-glycosylation in the LDL pathway may represent a novel therapeutic strategy to reduce LDL-C and cardiovascular disease.	Nitrogen	169-170	component of oligomeric golgi complex 2	Homo sapiens	11-16
31050353-0	2019	Arabidopsis ubiquitin-specific proteases UBP12 and UBP13 shape ORE1 levels during leaf senescence induced by nitrogen deficiency.	Nitrogen	109-117	NAC domain containing protein 6	Arabidopsis thaliana	63-67
31050353-1	2019	Nitrogen deficiency (-N) in plants triggers leaf senescence which is regulated by the transcription factor ORE1.	Nitrogen	0-8	NAC domain containing protein 6	Arabidopsis thaliana	107-111
31050353-3	2019	Here, we show that UBP12/UBP13 (ubiquitin-specific protease 12/13) antagonize the action of NLA (nitrogen limitation adaptation) E3 ligase to maintain ORE1 homeostasis.	Nitrogen	97-105	NAC domain containing protein 6	Arabidopsis thaliana	151-155
31280571-0	2019	Tailoring the Adsorption of ACE-Inhibiting Peptides by Nitrogen Functionalization of Porous Carbons.	Nitrogen	55-63	angiotensin I converting enzyme	Homo sapiens	28-31
31280571-3	2019	This study focuses on the impact of nitrogen functionalization of porous carbon adsorbents, either via pre- or post-treatment, on the adsorption behavior of the ACE-inhibiting peptide IW and the essential amino acid tryptophan (W).	Nitrogen	36-44	angiotensin I converting enzyme	Homo sapiens	161-164
31356625-5	2019	Silencing by RNA interference of the soluble N-ethylmaleimide-sensitive-factor attachment protein receptors Sec22b and syntaxin-5, which regulate ER-Golgi trafficking, identified these host proteins as components of the machinery that mediates the spreading of Leishmania effectors within host cells.	Nitrogen	14-15	SEC22 homolog B, vesicle trafficking protein	Homo sapiens	108-114
31444868-4	2019	Tafazzin (Taz) is a mitochondrial-specific transacylase that regulates mature cardiolipin (CL) formation, and its absence leads to mitochondrial dysfunction and excessive production of reactive oxygen/nitrogen species (ROS/RNS).	Nitrogen	201-209	tafazzin, phospholipid-lysophospholipid transacylase	Mus musculus	0-8
31444868-4	2019	Tafazzin (Taz) is a mitochondrial-specific transacylase that regulates mature cardiolipin (CL) formation, and its absence leads to mitochondrial dysfunction and excessive production of reactive oxygen/nitrogen species (ROS/RNS).	Nitrogen	201-209	tafazzin, phospholipid-lysophospholipid transacylase	Mus musculus	10-13
30737551-8	2019	Age, preoperative urea nitrogen (UN) and the preoperative albumin-to-bilirubin index (ALBI) showed the highest area under the curve (AUC) for the discontinuation of S-1 adjuvant within 6 months in each category: body status, blood tests and indices.	Nitrogen	23-31	proteasome 26S subunit, non-ATPase 1	Homo sapiens	165-168
31363918-0	2019	Carbon dots co-doped with nitrogen and chlorine for "off-on" fluorometric determination of the activity of acetylcholinesterase and for quantification of organophosphate pesticides.	Nitrogen	26-34	acetylcholinesterase (Cartwright blood group)	Homo sapiens	107-127
31117816-11	2019	Given that LDL-C was also reduced in a group of clinically unaffected heterozygotes, we propose that increasing LDL receptor-mediated cholesterol clearance by targeting N-glycosylation in the LDL pathway may represent a novel therapeutic strategy to reduce LDL-C and cardiovascular disease.	Nitrogen	169-170	component of oligomeric golgi complex 2	Homo sapiens	257-262
31325812-3	2019	Using linear regression, we found that neighbourhood-level nitrogen dioxide predicted later levels of fibrinogen, but not C-reactive protein.	Nitrogen	59-67	fibrinogen beta chain	Homo sapiens	102-112
31339941-8	2019	Soil nitrogen has more than doubled, ranging from 4.1 Mg ha-1 in the vineyard to 8.8 Mg ha-1 in old growth forest.	Nitrogen	5-13	Rho GTPase activating protein 45	Homo sapiens	57-61
31339941-8	2019	Soil nitrogen has more than doubled, ranging from 4.1 Mg ha-1 in the vineyard to 8.8 Mg ha-1 in old growth forest.	Nitrogen	5-13	Rho GTPase activating protein 45	Homo sapiens	88-92
31312984-4	2019	In this study, the N- and alpha-carbon oxidation processes of lapatinib catalyzed by CYP3A4 were explored by density functional theory method.	Nitrogen	19-20	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	85-91
31302781-0	2019	Electrochemical sandwich aptasensor for the carcinoembryonic antigen using graphene quantum dots, gold nanoparticles and nitrogen doped graphene modified electrode and exploiting the peroxidase-mimicking activity of a G-quadruplex DNAzyme.	Nitrogen	121-129	CEA cell adhesion molecule 3	Homo sapiens	44-68
30954800-4	2019	In addition, it even performs a low detection limit to Cu2+ for only 0.45 muM, which exhibits a higher selective detection to Cu2+ than other reported N-containing chemosenors.	Nitrogen	151-152	latexin	Homo sapiens	74-77
31102220-3	2019	The results showed that NO3- was the main nitrogen form in both the dry and wet seasons, but dissolved organic nitrogen (DON) was increased in the wet season.	Nitrogen	42-50	NBL1, DAN family BMP antagonist	Homo sapiens	24-27
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	35-36	estrogen receptor 1	Homo sapiens	189-212
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	54-55	estrogen receptor 1	Homo sapiens	189-212
31854731-2	2019	The results showed that the nitrogen concentration ranged from 4.43 to 13.83 mg L-1 in four park water bodies, which exhibited notable nitrogen pollution characteristics.	Nitrogen	28-36	immunoglobulin kappa variable 1-16	Homo sapiens	80-83
31854731-2	2019	The results showed that the nitrogen concentration ranged from 4.43 to 13.83 mg L-1 in four park water bodies, which exhibited notable nitrogen pollution characteristics.	Nitrogen	135-143	immunoglobulin kappa variable 1-16	Homo sapiens	80-83
31284656-6	2019	Besides, when the soil particle sizes ranged 0.18-0.28 mm, the soil nitrogen prediction accuracy was the best based on the partial least squares (PLS) model with the highest Rp2 of 0.983, the residual predictive deviation (RPD) of 6.706.	Nitrogen	68-76	RP2 activator of ARL3 GTPase	Homo sapiens	174-177
31270632-12	2019	Graphical abstract Schematic presentation of the quenching of the fluorescence of phosphorus and nitrogen dually-doped carbon quantum dots (PN-CQDs) by vitamin B12 (VB12) and Co(II).	Nitrogen	97-105	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	175-181
31575843-6	2019	Serum levels of ET-1 were positively associated with N-terminal pro-brain natriuretic peptide (NT-proBNP) (r = 0.27, p &lt; 0.05) and with C-reactive protein (CRP) (r = 0.36, p &lt; 0.05).	Nitrogen	53-54	endothelin 1	Homo sapiens	16-20
31028057-2	2019	A previous study involving human hepatocytes showed the primary route of midazolam metabolism, 1"-hydroxylation, shifted to N-glucuronidation in the presence of the CYP3A inhibitor ketoconazole, which may lead to an overprediction of the magnitude of a xenobiotic-midazolam interaction.	Nitrogen	124-125	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	165-170
31215021-5	2019	Moreover, accumulating evidence indicates that N-glycans have a major role in preventing the impairment of glucose-stimulated insulin secretion by maintaining the glucose transporter in proper orientation, indicating that interindividual variation in protein N-glycosylation might be a novel risk factor contributing to diabetes development.	Nitrogen	47-48	insulin	Homo sapiens	126-133
31098956-1	2019	N-linked glycosylation is one of the most common protein PTMs, and the topological structure (monosaccharide composition and sequence as well as glycosidic linkages) of N-glycans is vital information to understand their biological functions and roles.	Nitrogen	0-1	parathymosin	Mus musculus	57-61
30916996-1	2019	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex comprises synaptosome-associated protein of 25 kDa (SNAP25), syntaxin-1a (syx-1), and synaptobrevin 2, which is essential for many physiologic processes requiring membrane fusion.	Nitrogen	12-13	vesicle associated membrane protein 2	Homo sapiens	176-191
31266720-5	2019	Electrophoresis of serum transferrin found an abnormal N-glycosylation profile suggestive of CDG type 1 (decreased tetrasialotransferrin, increased disialo- and asialotransferrin).	Nitrogen	55-56	transferrin	Homo sapiens	25-36
31055873-4	2019	Further studies are warranted to define the molecular mechanisms through which N- and O-linked sialylation impacts upon the multiple biological activities of VWF.	Nitrogen	79-80	von Willebrand factor	Homo sapiens	158-161
31100640-9	2019	Furthermore, LDHA/PDHA1 changes in HNSCC cells resulted in a broad metabolic reprogramming while intracellular molecules including polyunsaturated fatty acids and nitrogen metabolism related metabolites underlie the malignant changes.	Nitrogen	163-171	lactate dehydrogenase A	Homo sapiens	13-17
30637733-8	2019	The upregulation of miR-424 improved renal lesion and DN symptoms of blood glucose level, urine protein level, body weight, creatinine level, blood urea nitrogen, and KW/BW ratio.	Nitrogen	153-161	microRNA 424	Homo sapiens	20-27
31071333-2	2019	We showed recently, through genetic ablation of the MGAT1 gene, which encodes an essential glycosyltransferase (GlcNAcT1), that prevention of cardiomyocyte hybrid/complex N-glycosylation was sufficient to cause DCM that led to heart failure and early death.	Nitrogen	115-116	mannoside acetylglucosaminyltransferase 1	Mus musculus	52-57
31465019-0	2019	Correction to "Nitrogen-Doped Nanoporous Carbon Nanospheroids for Selective Dye Adsorption and Pb(II) Ion Removal from Waste Water".	Nitrogen	15-23	submaxillary gland androgen regulated protein 3B	Homo sapiens	95-101
30238472-5	2019	The results suggest that the inverse regulation of ZmUPB1 and ZmPRX112 transcription observed in cells of the TZ in response to nitrogen depletion or NO3 - supply affects the balance between superoxide (O2  - ) and hydrogen peroxide (H2 O2 ) in the root apex and consequently triggers differential root growth.	Nitrogen	128-136	beta alanine synthase 1	Zea mays	51-57
31266730-0	2019	Pyramiding of the dep1-1 and NAL1NJ6 alleles achieves sustainable improvements in nitrogen-use efficiency and grain yield in japonica rice breeding.	Nitrogen	82-90	keratin-associated protein 5-5	Oryza sativa Japonica Group	18-22
31043477-5	2019	We, in this study, demonstrate that the MHC class I allele, Mamu-B*05104, binds the N-myristoylated 4-mer peptide (C14-Gly-Gly-Ala-Ile) derived from the viral Nef protein for its presentation to CTLs.	Nitrogen	84-85	S100 calcium binding protein B	Homo sapiens	159-162
31093688-7	2019	In this study, we show that this symptom, similar to the Cu deficiency, occurred in the presence of high N largely depending on SPL7, suggesting that plants actually sensed Cu deficiency.	Nitrogen	105-106	squamosa promoter binding protein-like 7	Arabidopsis thaliana	128-132
30811219-3	2019	NGI-1 is a small-molecule inhibitor of oligosaccharyltransferase (OST) complexes STT3A-OST and STT3B-OST, which catalyze cotranslational and post-translational N-glycosylation, respectively.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	66-69
30925289-6	2019	We also found that N-GQDs activated the cytochrome P450 monooxygenase (e.g. cyp1a) and the associated aryl-hydrocarbon receptor repressors (ahrr1 and ahrr2) in zebrafish embryos.	Nitrogen	19-20	cytochrome P450, family 1, subfamily A	Danio rerio	76-81
30925289-6	2019	We also found that N-GQDs activated the cytochrome P450 monooxygenase (e.g. cyp1a) and the associated aryl-hydrocarbon receptor repressors (ahrr1 and ahrr2) in zebrafish embryos.	Nitrogen	19-20	aryl-hydrocarbon receptor repressor a	Danio rerio	140-145
31263658-8	2019	In addition, payload-free NS@PPFA exhibited a high binding affinity (K d = 2.68 x 10-10 M) toward vascular endothelial growth factor (VEGF-A165), which was at least two orders of magnitude stronger than that of highly abundant plasma proteins, such as human serum albumin.	Nitrogen	26-28	vascular endothelial growth factor A	Homo sapiens	98-132
31263658-8	2019	In addition, payload-free NS@PPFA exhibited a high binding affinity (K d = 2.68 x 10-10 M) toward vascular endothelial growth factor (VEGF-A165), which was at least two orders of magnitude stronger than that of highly abundant plasma proteins, such as human serum albumin.	Nitrogen	26-28	vascular endothelial growth factor A	Homo sapiens	134-138
31263658-9	2019	Furthermore, in vitro study showed that NS@PPFA could effectively inhibit VEGF-A165-induced proliferation, migration, and tube formation of human umbilical vein endothelial cells, resulting in additional therapeutic benefits for eradicating tumors through a simultaneous antiangiogenic action in chemo-photothermal treatment.	Nitrogen	40-42	vascular endothelial growth factor A	Homo sapiens	74-78
30811219-3	2019	NGI-1 is a small-molecule inhibitor of oligosaccharyltransferase (OST) complexes STT3A-OST and STT3B-OST, which catalyze cotranslational and post-translational N-glycosylation, respectively.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	87-90
30811219-3	2019	NGI-1 is a small-molecule inhibitor of oligosaccharyltransferase (OST) complexes STT3A-OST and STT3B-OST, which catalyze cotranslational and post-translational N-glycosylation, respectively.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	87-90
30811219-6	2019	N-glycosylation of 2 representative envelope proteins (gC and gD) was primarily dependent upon STT3A-OST, but to a large extent replaceable by STT3B-OST.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	101-104
30811219-6	2019	N-glycosylation of 2 representative envelope proteins (gC and gD) was primarily dependent upon STT3A-OST, but to a large extent replaceable by STT3B-OST.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	149-152
30811219-8	2019	However, with cells lacking STT3B-OST activity (missing the catalytic subunit STT3B or the oxidoreductase subunits magnesium transporter 1/tumor suppressor candidate 3) and thus solely dependent upon STT3A-OST for N-glycosylation, NGI-1 treatment resulted in HSV-1 having cell type-dependent dysfunction (affecting infectivity with Vero cells much more than with the 293 lines).	Nitrogen	214-215	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	206-209
30850862-2	2019	Glutamine synthetase (GS) plays a key role in plant nitrogen metabolism and photorespiration.	Nitrogen	52-60	glutamate-ammonia ligase	Homo sapiens	0-20
30969900-0	2019	N-glycosylation-dependent regulation of hK2P17.1 currents.	Nitrogen	0-1	potassium two pore domain channel subfamily K member 17	Homo sapiens	40-48
30969900-10	2019	Channel subunits of hK2P17.1 harbor two functional N-glycosylation sites at positions N65 and N94.	Nitrogen	51-52	potassium two pore domain channel subfamily K member 17	Homo sapiens	20-28
30969900-12	2019	Disruption of both N-glycosylation sites results in loss of hK2P17.1 currents, presumably caused by impaired surface expression.	Nitrogen	19-20	potassium two pore domain channel subfamily K member 17	Homo sapiens	60-68
31046224-0	2019	Interfacial Property Modulation of PIM-1 through Polydopamine-Derived Submicrospheres for Enhanced CO2/N2 Separation Performance.	Nitrogen	103-105	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	35-40
30947043-5	2019	The optimal conditions for PHA accumulation were a crude glycerin concentration of 8954 mg COD/L with a C:N ratio of 15.9 mg C/mg N-NH4, which gave a Yobs,BA of 0.29 mg CODBA/mg COD, a Yobs,PHA of 0.28 mg CODPHA/mg COD, a XPHA of 55.6% VSS and a PrV of 757.3 mg CODPHA/L d (550.0 mg PHA/L d).	Nitrogen	106-107	lamin B receptor	Homo sapiens	27-30
31151284-9	2019	AIs and N/DSs sharing the cytochrome P450 pathway are at risk of negative interactions.	Nitrogen	8-9	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	26-41
30884075-4	2019	When the resulting CoII -H species was exposed to N2 , H2 evolution readily occurs at ambient conditions.	Nitrogen	50-52	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	19-23
30864421-6	2019	The reactive oxygen (ROS) and reactive nitrogen species (RNS) are the most important endogenous sources produced by non-enzymatic and enzymatic [myeloperoxidase (MPO), nicotinamide adenine dinucleotide phosphate (NADH) oxidase and lipoxygenase (LO)] reactions that may be balanced with anti-oxidative compounds [glutathione (GSH), polyphenols and vitamins] and enzymes [glutathione peroxidase (Gpx), peroxiredoxins (Prdx), superoxide dismutase (SOD) and paraoxonase (PON)].	Nitrogen	39-47	myeloperoxidase	Homo sapiens	145-160
30864421-6	2019	The reactive oxygen (ROS) and reactive nitrogen species (RNS) are the most important endogenous sources produced by non-enzymatic and enzymatic [myeloperoxidase (MPO), nicotinamide adenine dinucleotide phosphate (NADH) oxidase and lipoxygenase (LO)] reactions that may be balanced with anti-oxidative compounds [glutathione (GSH), polyphenols and vitamins] and enzymes [glutathione peroxidase (Gpx), peroxiredoxins (Prdx), superoxide dismutase (SOD) and paraoxonase (PON)].	Nitrogen	39-47	myeloperoxidase	Homo sapiens	162-165
30864421-6	2019	The reactive oxygen (ROS) and reactive nitrogen species (RNS) are the most important endogenous sources produced by non-enzymatic and enzymatic [myeloperoxidase (MPO), nicotinamide adenine dinucleotide phosphate (NADH) oxidase and lipoxygenase (LO)] reactions that may be balanced with anti-oxidative compounds [glutathione (GSH), polyphenols and vitamins] and enzymes [glutathione peroxidase (Gpx), peroxiredoxins (Prdx), superoxide dismutase (SOD) and paraoxonase (PON)].	Nitrogen	39-47	dual oxidase 2	Homo sapiens	168-243
30864421-6	2019	The reactive oxygen (ROS) and reactive nitrogen species (RNS) are the most important endogenous sources produced by non-enzymatic and enzymatic [myeloperoxidase (MPO), nicotinamide adenine dinucleotide phosphate (NADH) oxidase and lipoxygenase (LO)] reactions that may be balanced with anti-oxidative compounds [glutathione (GSH), polyphenols and vitamins] and enzymes [glutathione peroxidase (Gpx), peroxiredoxins (Prdx), superoxide dismutase (SOD) and paraoxonase (PON)].	Nitrogen	39-47	paraoxonase 1	Homo sapiens	467-470
31112557-1	2019	Nitrification, the microbial oxidation of ammonia (NH3) to nitrite (NO2-) and NO2- to nitrate (NO3-), plays a vital role in ocean nitrogen cycling.	Nitrogen	130-138	NBL1, DAN family BMP antagonist	Homo sapiens	95-98
30768269-4	2019	The early response of CL-20/TNT to thermal stimulus is dominated by N-NO2 bond cleavage for NO2 formation and C-N bond scission leading to ring-opening of CL-20.	Nitrogen	29-30	epithelial membrane protein 1	Homo sapiens	22-27
30768269-4	2019	The early response of CL-20/TNT to thermal stimulus is dominated by N-NO2 bond cleavage for NO2 formation and C-N bond scission leading to ring-opening of CL-20.	Nitrogen	29-30	epithelial membrane protein 1	Homo sapiens	155-160
30948514-3	2019	Human rhodopsin is N-glycosylated on Asn2 and Asn15, whereas human (h) red and green cone opsins (hOPSR and hOPSG, respectively) are N-glycosylated at Asn34 Here, utilizing a monoclonal antibody (7G8 mAB), we demonstrate that hOPSR and hOPSG from human retina also are O-glycosylated with full occupancy.	Nitrogen	19-20	rhodopsin	Homo sapiens	6-15
31076624-3	2019	Subsequently, 2-9 nm N, S-GQDs are successfully decorated onto 30-50 nm Au-PANI nanowires by Au-thiol linkage to serve as the bifunctional probe for amplifying the electrochemical activity as well as anchoring anti-CEA.	Nitrogen	21-22	CEA cell adhesion molecule 3	Homo sapiens	215-218
31068202-8	2019	A prognostic score (We denoted it as the SABP score), ranging from 0 to 10, consisting of systemic inflammatory response syndrome, serum albumin, blood urea nitrogen and pleural effusion, was developed by logistic regression and bootstrapping analysis.	Nitrogen	157-165	prolactin induced protein	Homo sapiens	41-45
30989158-0	2019	Direct intramolecular carbon(sp2)-nitrogen(sp2) reductive elimination from gold(iii).	Nitrogen	34-42	Sp2 transcription factor	Homo sapiens	29-32
30989158-0	2019	Direct intramolecular carbon(sp2)-nitrogen(sp2) reductive elimination from gold(iii).	Nitrogen	34-42	Sp2 transcription factor	Homo sapiens	43-46
30951298-5	2019	The central transition-metal ion M n+ (MnII, FeIII, CoII, NiII, CuII, ZnII, PdII) in the POP structure and also the nature of the capping group (AsO43-, SeO32-, PO43-, phenyl-AsO32-) influence the resulting catalytic performance.	Nitrogen	35-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	52-56
31157201-5	2019	These results suggest that hydrogen bonding interactions between the nitrogens of the pyrazine ring and the SLC35F2 protein are critical for entry of YM155 into hPSCs, and hence stemotoxic activity.	Nitrogen	69-78	solute carrier family 35 member F2	Homo sapiens	108-115
30782366-5	2019	And the detection limits were down to 0.1 muM (S/N = 3) for both analytes.	Nitrogen	49-50	latexin	Homo sapiens	42-45
31087872-4	2019	The nitrogen removal efficiency was optimum when the COD concentration was between 15.00 and 30.00 mg L-1.	Nitrogen	4-12	immunoglobulin kappa variable 1-16	Homo sapiens	102-105
30950275-2	2019	The Rh2(OAc)4-mediated selective C(sp2)-H insertion at the ortho-position of 2-aryl group (R1) of the furan moiety under N2 atmosphere occurred to construct naphthalene cycle, affording trifunctionalized naphtho[1,2- b]furans.	Nitrogen	121-123	Sp2 transcription factor	Homo sapiens	33-38
30878866-1	2019	Elimination of nitrogen pollution from wastewater containing high-strength nitrate (NO3--N) is a significant issue to prevent deterioration of water quality and eutrophication of receiving water body.	Nitrogen	15-23	NBL1, DAN family BMP antagonist	Homo sapiens	84-87
30833465-10	2019	Finally, we argue that glucagon is a bona fide postprandial hormone that evolved to concurrently and synergistically work with insulin to regulate glucose, amino acid, and nitrogen metabolism.	Nitrogen	172-180	insulin	Homo sapiens	127-134
30744926-5	2019	The nitrogen removal rate was decreased by long-term addition of 10 mg L-1 Zn(II).	Nitrogen	4-12	L1 cell adhesion molecule	Homo sapiens	71-74
30878866-6	2019	Results showed that a satisfactory nitrogen removal was achieved by optimizing the volume ratios of influent NO3--N and municipal sewage, as well as the external organic matter dosage.	Nitrogen	35-43	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
30776171-1	2019	Increasing nitrogen (N) deposition in subtropical forests in south China causes N saturation, associated with significant nitrate (NO3 - ) leaching.	Nitrogen	11-19	NBL1, DAN family BMP antagonist	Homo sapiens	131-134
30784837-3	2019	This study measured nitrogen (N) isotopes of NO3- (hereafter as delta15N-NO3-) in PM2.5 collected at Beijing in 2014.	Nitrogen	20-28	NBL1, DAN family BMP antagonist	Homo sapiens	45-48
30784837-8	2019	Annually, NOx from coal combustion, vehicle exhausts, biomass burning, and microbial N cycle contributed 28 +- 12%, 29 +- 17%, 27 +- 15%, and 16 +- 7% to NO3- in PM2.5, respectively, showing actually comparable contributions between non-fossil NOx (43 +- 16%) and fossil NOx (57 +- 21%).	Nitrogen	10-11	NBL1, DAN family BMP antagonist	Homo sapiens	154-157
30700847-5	2019	Compared to wild-type (WT) mice with a renal IRI, IL-10 knockout (IL-10 KO) mice with IRI demonstrated decreased renal function as represented by blood urea nitrogen and serum creatinine, upregulated early acute kidney injury (AKI) biomarkers such as kidney injury molecule-1 (Kim-1), increased mRNA expression of the pro-inflammatory cytokines IL-1beta, IL-6, and IL-18 and a chemokine (regulated on activation, normal T cell expressed and secreted; RANTES), and increased expression of the pro-apoptosis factors Bax and cleaved caspase-3.	Nitrogen	157-165	interleukin 10	Mus musculus	50-55
30660986-1	2019	Present investigation demonstrates that push electron effect of nitrogen in M ... NH3is reduced rather than enhanced upon lithiation which has been explained by natural bond orbital analysis showing that nitrogen atom in NLi3 changes it"s state of hybridization from sp3 to sp2 leaving the 2pz orbital partially occupied.	Nitrogen	64-72	Sp3 transcription factor	Homo sapiens	267-270
30660986-1	2019	Present investigation demonstrates that push electron effect of nitrogen in M ... NH3is reduced rather than enhanced upon lithiation which has been explained by natural bond orbital analysis showing that nitrogen atom in NLi3 changes it"s state of hybridization from sp3 to sp2 leaving the 2pz orbital partially occupied.	Nitrogen	64-72	Sp2 transcription factor	Homo sapiens	274-277
30660986-1	2019	Present investigation demonstrates that push electron effect of nitrogen in M ... NH3is reduced rather than enhanced upon lithiation which has been explained by natural bond orbital analysis showing that nitrogen atom in NLi3 changes it"s state of hybridization from sp3 to sp2 leaving the 2pz orbital partially occupied.	Nitrogen	204-212	Sp3 transcription factor	Homo sapiens	267-270
30660986-1	2019	Present investigation demonstrates that push electron effect of nitrogen in M ... NH3is reduced rather than enhanced upon lithiation which has been explained by natural bond orbital analysis showing that nitrogen atom in NLi3 changes it"s state of hybridization from sp3 to sp2 leaving the 2pz orbital partially occupied.	Nitrogen	204-212	Sp2 transcription factor	Homo sapiens	274-277
31041529-4	2019	The PdNPs quench the green fluorescence of the FAM-AFP aptamer via interactions between nitrogen functional groups of the AFP aptamer and PdNPs.	Nitrogen	88-96	alpha fetoprotein	Homo sapiens	51-54
31041529-4	2019	The PdNPs quench the green fluorescence of the FAM-AFP aptamer via interactions between nitrogen functional groups of the AFP aptamer and PdNPs.	Nitrogen	88-96	alpha fetoprotein	Homo sapiens	122-125
30801123-3	2019	Here we report the development of a three-dimensional canopy photosynthesis model (3dCAP), which effectively combines three-dimensional canopy architecture, canopy vertical nitrogen distribution, a ray-tracing algorithm, and a leaf photosynthesis model.	Nitrogen	173-181	CAP	Drosophila melanogaster	84-88
30995910-6	2019	The CREL contains a single predicted N-glycosylation site, which we show bears a sugar modification in recombinantly expressed IR8a.	Nitrogen	37-38	Ionotropic receptor 8a	Drosophila melanogaster	127-131
30860543-2	2019	The introduction of a single aromatic moiety into non-protected polyamine molecules was achieved using the commercially available Pd(dba)2/BINAP precatalyst to afford nitrogen chelators, in which the aromatic signalling unit is directly attached to the polyamine residue.	Nitrogen	167-175	DBA2	Homo sapiens	130-138
31003454-5	2019	Interesting correlations (r) were estimated between beta-CN, kappa-CN and beta-LG, expressed as percentage of crude protein, and milk urea nitrogen (r = 0.31, -0.20 and -0.26, respectively) and between alpha-LA and fat percentage (r = 0.41).	Nitrogen	139-147	Weaning weight-maternal milk	Bos taurus	129-133
30999674-4	2019	Ripened cow"s milk cheese had higher values of WSN/TN (water-soluble nitrogen per total nitrogen content) and TCA-SN/TN (nitrogen soluble in 12% trichloroacetic acid per total nitrogen), but similar PTA-SN/TN (nitrogen soluble in 5% phosphotungstic acid per total nitrogen) values were observed in ripened cheeses.	Nitrogen	69-77	Weaning weight-maternal milk	Bos taurus	14-18
30999674-4	2019	Ripened cow"s milk cheese had higher values of WSN/TN (water-soluble nitrogen per total nitrogen content) and TCA-SN/TN (nitrogen soluble in 12% trichloroacetic acid per total nitrogen), but similar PTA-SN/TN (nitrogen soluble in 5% phosphotungstic acid per total nitrogen) values were observed in ripened cheeses.	Nitrogen	88-96	Weaning weight-maternal milk	Bos taurus	14-18
30999674-4	2019	Ripened cow"s milk cheese had higher values of WSN/TN (water-soluble nitrogen per total nitrogen content) and TCA-SN/TN (nitrogen soluble in 12% trichloroacetic acid per total nitrogen), but similar PTA-SN/TN (nitrogen soluble in 5% phosphotungstic acid per total nitrogen) values were observed in ripened cheeses.	Nitrogen	88-96	Weaning weight-maternal milk	Bos taurus	14-18
30999674-4	2019	Ripened cow"s milk cheese had higher values of WSN/TN (water-soluble nitrogen per total nitrogen content) and TCA-SN/TN (nitrogen soluble in 12% trichloroacetic acid per total nitrogen), but similar PTA-SN/TN (nitrogen soluble in 5% phosphotungstic acid per total nitrogen) values were observed in ripened cheeses.	Nitrogen	88-96	Weaning weight-maternal milk	Bos taurus	14-18
30999674-4	2019	Ripened cow"s milk cheese had higher values of WSN/TN (water-soluble nitrogen per total nitrogen content) and TCA-SN/TN (nitrogen soluble in 12% trichloroacetic acid per total nitrogen), but similar PTA-SN/TN (nitrogen soluble in 5% phosphotungstic acid per total nitrogen) values were observed in ripened cheeses.	Nitrogen	88-96	Weaning weight-maternal milk	Bos taurus	14-18
30999674-4	2019	Ripened cow"s milk cheese had higher values of WSN/TN (water-soluble nitrogen per total nitrogen content) and TCA-SN/TN (nitrogen soluble in 12% trichloroacetic acid per total nitrogen), but similar PTA-SN/TN (nitrogen soluble in 5% phosphotungstic acid per total nitrogen) values were observed in ripened cheeses.	Nitrogen	88-96	Weaning weight-maternal milk	Bos taurus	14-18
31025190-1	2019	Natural hIFNgamma is a glycoprotein with two N-glycosylation sites in each monomer chain, which are independently and differentially glycosylated.	Nitrogen	0-1	interferon gamma	Homo sapiens	8-17
31000788-3	2019	The ORF2 protein sequence contains three highly conserved potential N-glycosylation sites (N1, N2 and N3).	Nitrogen	68-69	capsid protein	Orthohepevirus A	4-8
31000788-4	2019	The status and biological relevance of ORF2 N-glycosylation in HEV lifecycle remain to be elucidated.	Nitrogen	44-45	capsid protein	Orthohepevirus A	39-43
31000788-5	2019	Here, we generated and extensively characterized a series of ORF2 mutants in which the three N-glycosylation sites were mutated individually or in combination.	Nitrogen	93-94	capsid protein	Orthohepevirus A	61-65
31000788-7	2019	We showed that N-glycosylation of ORF2 protein does not play any role in replication and assembly of infectious HEV particles.	Nitrogen	15-16	capsid protein	Orthohepevirus A	34-38
30995910-7	2019	Using the Drosophila olfactory system as an in vivo model, we find that a transgenically encoded IR8a mutant in which the CREL cannot be N-glycosylated is impaired in localisation to cilia in some, though not all, populations of sensory neurons expressing different tuning IRs.	Nitrogen	137-138	Ionotropic receptor 8a	Drosophila melanogaster	97-101
31087933-3	2019	The results showed that with an influent total nitrogen (TN) of 40 mg L-1, the optimal HRT of the No.1 reactor was 2.5 h, and the removal rate and effluent concentration of TN were stable at 72.2% and 10.55 mg L-1, respectively.	Nitrogen	47-55	immunoglobulin kappa variable 1-16	Homo sapiens	70-73
30979007-9	2019	Overall, these results support N-linked glycosylation as an unprecedented post-translational modification that may modulate eCB-binding receptors" expression and localization, in particular for CB1.	Nitrogen	31-32	cannabinoid receptor 1	Homo sapiens	194-197
30743916-3	2019	The mean concentration of total dissolved nitrogen (TDN) in the two catchments was 0.63 mg L-1, which is generally higher than other permafrost catchments around the Arctic Ocean.	Nitrogen	42-50	immunoglobulin kappa variable 1-16	Homo sapiens	91-94
30877228-9	2019	Additionally, SGLT1-like could partake in urea absorption, as T. squamosa is known to conduct light-enhanced urea uptake to benefit the nitrogen-deficient zooxanthellae.	Nitrogen	136-144	solute carrier family 5 member 1	Homo sapiens	14-19
30992998-11	2019	The analysis of the gdh2/gdh2 and the gdh3/gdh3 mutants confirmed our hypothesis that redox potential and nitrogen metabolism are related to filament formation and identified these metabolic pathways as potential drug targets to inhibit morphogenesis.	Nitrogen	106-114	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	38-42
30992998-11	2019	The analysis of the gdh2/gdh2 and the gdh3/gdh3 mutants confirmed our hypothesis that redox potential and nitrogen metabolism are related to filament formation and identified these metabolic pathways as potential drug targets to inhibit morphogenesis.	Nitrogen	106-114	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	43-47
30996242-4	2019	Ang II-infused mice exhibited hypertension, cardiac hypertrophy, increases in blood urea nitrogen and serum creatinine, moderate albuminuria and renal pathological changes such as mild urinary cast, interstitial macrophage infiltration and modest interstitial fibrosis.	Nitrogen	89-97	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	0-6
30912932-5	2019	Comparison of the subseries and individual compounds showed that CYP3A4 only weakly discriminates between side-group configurations, associates more tightly with the pyridyl-ethyl-linker analogues, and strongly disfavors the N-containing backbone.	Nitrogen	225-226	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	65-71
30989397-10	2019	Graphical abstract Schematic presentation of the synthesis of nitrogen and copper co-doped carbon dots (N,Cu-CDs) and their application as an enzyme mimic for colorimetric discrimination of ortho-, meta- and para-phenylenediamine (OPD, MPD and PPD).	Nitrogen	62-70	mevalonate diphosphate decarboxylase	Homo sapiens	236-239
33267110-4	2019	With an increasing N2 flow rate, the film deposited at a RN of 50% had the highest hardness (12.4 GPa), the highest modulus (169 GPa), a small roughness, and a beautiful color.	Nitrogen	19-21	glycophorin A (MNS blood group)	Homo sapiens	98-101
33267110-4	2019	With an increasing N2 flow rate, the film deposited at a RN of 50% had the highest hardness (12.4 GPa), the highest modulus (169 GPa), a small roughness, and a beautiful color.	Nitrogen	19-21	glycophorin A (MNS blood group)	Homo sapiens	129-132
30992998-7	2019	While the gdh3/gdh3 mutant could grow on these carbon and nitrogen sources, the strain was locked in the yeast morphology in proline-containing medium.	Nitrogen	58-66	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	10-14
30992998-7	2019	While the gdh3/gdh3 mutant could grow on these carbon and nitrogen sources, the strain was locked in the yeast morphology in proline-containing medium.	Nitrogen	58-66	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	15-19
31087936-2	2019	The study found that when the influent salinity was increased to 15 g L-1 and 30 g L-1, the nitrogen removal performance of the reactor decreased slightly, but was restored with the extension of the running time.	Nitrogen	92-100	L1 cell adhesion molecule	Homo sapiens	70-86
31087940-4	2019	The results showed that the dissolved N2O concentration in the agricultural headwater stream ranged from 0.26 to 1.28 mug L-1 with an annual mean value of 0.57 mug L-1, with nitrate (NO3--N, with an annual mean concentration of 1.45 mg L-1) as the predominant reactive N form.	Nitrogen	38-39	L1 cell adhesion molecule	Homo sapiens	122-125
30637965-0	2019	Atomic Layer Deposition of NiOOH/Ni(OH)2 on PIM-1-Based N-Doped Carbon Nanofibers for Electrochemical Water Splitting in Alkaline Medium.	Nitrogen	27-28	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	44-49
31087940-4	2019	The results showed that the dissolved N2O concentration in the agricultural headwater stream ranged from 0.26 to 1.28 mug L-1 with an annual mean value of 0.57 mug L-1, with nitrate (NO3--N, with an annual mean concentration of 1.45 mg L-1) as the predominant reactive N form.	Nitrogen	38-39	L1 cell adhesion molecule	Homo sapiens	164-167
30637965-3	2019	Well-aligned high-surface-area electrospun polymers of intrinsic microporosity (PIM-1)-based nitrogen-doped carbon nanofibers were prepared as a free-standing flexible electrode.	Nitrogen	93-101	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	80-85
31087940-4	2019	The results showed that the dissolved N2O concentration in the agricultural headwater stream ranged from 0.26 to 1.28 mug L-1 with an annual mean value of 0.57 mug L-1, with nitrate (NO3--N, with an annual mean concentration of 1.45 mg L-1) as the predominant reactive N form.	Nitrogen	38-39	NBL1, DAN family BMP antagonist	Homo sapiens	183-186
30637965-8	2019	This study provides insight into the design of 1D-aligned N-doped PIM-1 electrospun carbon nanofibers as a flexible and free-standing NiOOH/Ni(OH)2 decorated electrode as a highly stable nanocatalyst for water splitting in an alkaline medium.	Nitrogen	58-59	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	66-71
31087940-4	2019	The results showed that the dissolved N2O concentration in the agricultural headwater stream ranged from 0.26 to 1.28 mug L-1 with an annual mean value of 0.57 mug L-1, with nitrate (NO3--N, with an annual mean concentration of 1.45 mg L-1) as the predominant reactive N form.	Nitrogen	38-39	L1 cell adhesion molecule	Homo sapiens	164-167
30821452-6	2019	For the electron-donating groups, the two isomers bonded to the sp3-hybridized carbon or nitrogen atom are almost isoenergetic.	Nitrogen	89-97	Sp3 transcription factor	Homo sapiens	64-67
30821452-7	2019	When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom.	Nitrogen	45-53	Sp3 transcription factor	Homo sapiens	174-177
30821452-7	2019	When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom.	Nitrogen	45-53	Sp3 transcription factor	Homo sapiens	174-177
30821452-7	2019	When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom.	Nitrogen	307-315	Sp2 transcription factor	Homo sapiens	10-13
30821452-7	2019	When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom.	Nitrogen	307-315	Sp3 transcription factor	Homo sapiens	19-22
30821452-7	2019	When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom.	Nitrogen	307-315	Sp3 transcription factor	Homo sapiens	174-177
30821452-7	2019	When both sp2- and sp3-hybridized carbon and nitrogen atoms in the five-membered ring of indoliums are considered, the isomer with the polyaurated substituents bonded to the sp3-hybridized carbon atom is thermodynamically more stable than that with the polyaurated substituents bonded to the sp3-hybridized nitrogen atom.	Nitrogen	307-315	Sp3 transcription factor	Homo sapiens	174-177
30677534-6	2019	Computational analysis showed that these mutations may lead to remarkable changes in the conformational structure and asparagine (N)-linked glycosylation sites of S1-NTD, which may be associated with the altered pathogenicity of these variant PEDV strains.	Nitrogen	129-132	proteasome 26S subunit, non-ATPase 1	Homo sapiens	163-169
31019513-0	2019	N-Linked Glycosylation Regulates CD22 Organization and Function.	Nitrogen	0-2	CD22 molecule	Homo sapiens	33-37
31019513-5	2019	CD22 is highly glycosylated, containing 12 N-linked glycosylation sites on its extracellular domain, the function of which remain to be resolved.	Nitrogen	43-44	CD22 molecule	Homo sapiens	0-4
31019513-7	2019	To this end, we mutated five out of the six N-linked glycosylation residues on CD22 localized closest to the sialic acid binding site.	Nitrogen	44-45	CD22 molecule	Homo sapiens	79-83
31019513-13	2019	Taken together, these findings implicate N-linked glycosylation in the organization and function of CD22, likely through regulating heterotypic interactions between CD22 and its binding partners.	Nitrogen	41-42	CD22 molecule	Homo sapiens	100-104
31019513-13	2019	Taken together, these findings implicate N-linked glycosylation in the organization and function of CD22, likely through regulating heterotypic interactions between CD22 and its binding partners.	Nitrogen	41-42	CD22 molecule	Homo sapiens	165-169
30957789-4	2019	The pseudo-octahedral coordination of the CoIII atom is completed by one phenolate O and one amidic N atom of the same arm of the bridging o-van-en ligand.	Nitrogen	100-101	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	42-47
30724472-2	2019	Herein, we report on a unique strategy to prepare Fe-Co-N-C-x (x refers to the pyrolysis temperature) electrocatalysts which involves anion-exchange of [Fe(CN)6 ]3- into a cationic CoII -based metal-organic framework precursor prior to heat treatment.	Nitrogen	56-57	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	181-185
30724472-4	2019	This is the first example of Fe-Co-N-C electrocatalysts fabricated from a cationic CoII -based MOF precursor that dopes the Fe element via anion-exchange, and our current work provides a new entrance towards MOF-derived transition-metal (e.g. Fe or Co) and nitrogen-codoped carbon electrocatalysts with excellent ORR activity.	Nitrogen	257-265	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	83-87
30824613-7	2019	However, 7D12-hcAb was equally ineffective as cetuximab in killing cells expressing the cetuximab/panitumumab-resistant aberrantly N-glycosylated EGFR R521K variant.	Nitrogen	131-132	epidermal growth factor receptor	Homo sapiens	146-150
30246502-4	2019	We constructed the N-glycosylation mutation plasmid of EpCAM and used it to treat breast cancer cells.	Nitrogen	19-20	epithelial cell adhesion molecule	Homo sapiens	55-60
30246502-5	2019	Loss of N-glycosylation at all three sites EpCAM had no effect on its level of expression or membrane localization.	Nitrogen	8-9	epithelial cell adhesion molecule	Homo sapiens	43-48
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	epithelial cell adhesion molecule	Homo sapiens	28-33
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	mitogen-activated protein kinase 1	Homo sapiens	74-77
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	AKT serine/threonine kinase 1	Homo sapiens	83-86
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	mitogen-activated protein kinase 1	Homo sapiens	114-117
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	AKT serine/threonine kinase 1	Homo sapiens	127-130
30246502-8	2019	Furthermore, we demonstrated that N-glycosylation mutation of EpCAM-mediated invasion and metastasis of breast carcinoma cells required the downregulation of MMP-9 via inhibition of these two signaling pathways.	Nitrogen	34-35	epithelial cell adhesion molecule	Homo sapiens	62-67
30684751-2	2019	Adopting zinc zeolitic imidazolate framework and graphitic carbon nitride as nitrogen-sources and templates, we herein design a facile route to fabricate an oxygen (6.11%) functionalized and heavy nitrogen (23.54%) doped porous carbon (NOC-800) with high graphitization degree, high surface area and total pore volume.	Nitrogen	77-85	nocturnin	Homo sapiens	236-239
30684751-2	2019	Adopting zinc zeolitic imidazolate framework and graphitic carbon nitride as nitrogen-sources and templates, we herein design a facile route to fabricate an oxygen (6.11%) functionalized and heavy nitrogen (23.54%) doped porous carbon (NOC-800) with high graphitization degree, high surface area and total pore volume.	Nitrogen	197-205	nocturnin	Homo sapiens	236-239
31096419-8	2019	High-resolution XPS spectra clearly illustrate the adsorption mechanism, in that Hg(II) preferentially binds to sulphur functional groups and Pb(II) tends to be adsorbed by nitrogen groups in poly(C3N3S3) matrix.	Nitrogen	173-181	submaxillary gland androgen regulated protein 3B	Homo sapiens	142-148
30983997-12	2019	B1R and iNOS appear to partake in a mutual auto-induction and amplification loop to enhance nitrogen species formation and inflammation in diabetic retina.	Nitrogen	92-100	bradykinin receptor B1	Rattus norvegicus	0-3
30983997-12	2019	B1R and iNOS appear to partake in a mutual auto-induction and amplification loop to enhance nitrogen species formation and inflammation in diabetic retina.	Nitrogen	92-100	nitric oxide synthase 2	Rattus norvegicus	8-12
30758007-4	2019	Nitrification of N-containing materials in the soil was possibly the major source of NO3- all year round, especially in the rainy season, whereas manure and sewage significantly contributed to the NO3- load in the Taige River in the dry season.	Nitrogen	0-1	NBL1, DAN family BMP antagonist	Homo sapiens	85-88
30882825-4	2019	For effective conjugation with Cu(ii)-bound Abeta complexes, we have designed carbon dots that possess nitrogen (N)-containing polyaromatic functionalities on their surface by employing o-phenylenediamine (OPD) as a polymerization precursor.	Nitrogen	103-111	amyloid beta precursor protein	Homo sapiens	44-49
30882825-4	2019	For effective conjugation with Cu(ii)-bound Abeta complexes, we have designed carbon dots that possess nitrogen (N)-containing polyaromatic functionalities on their surface by employing o-phenylenediamine (OPD) as a polymerization precursor.	Nitrogen	113-114	amyloid beta precursor protein	Homo sapiens	44-49
30677605-2	2019	In this study, lignin was successfully converted into porous carbon (LPC) in one step by microwave heating combined with the use of humidified nitrogen.	Nitrogen	143-151	proprotein convertase subtilisin/kexin type 7	Homo sapiens	69-72
30901997-3	2019	We considered a set of 21 complexes with the NHN hydrogen bond without proton transfer, including hydrogen bonds from weak to medium strong ones (2-21 kcal/mol), with neutral or anionic bases and with sp3 and sp2 hybridized nitrogen proton acceptors.	Nitrogen	224-232	Sp2 transcription factor	Homo sapiens	209-212
30871041-14	2019	Moreover, we have established that increasing the length of the alkyl chain at the quaternised nitrogen of the 4-(N-alkylpyridinium)-1,4-DHP molecule or the introduction of propargyl moieties in the 1,4-DHP molecule significantly influences the cytotoxicity on HT-1080 (human fibrosarcoma) and MH-22A (mouse hepatocarcinoma) cell lines, as well as the estimated basal cytotoxicity.	Nitrogen	95-103	dihydropyrimidinase	Homo sapiens	137-140
30889848-13	2019	This result implies that supercritical CO2 exposure has potential to limit physical aging performance loss in PIM-1 based membranes for O2/N2 separation.	Nitrogen	139-141	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	110-115
30711708-7	2019	The exposure of A549 cells to Ag/N-TiO2 NPs determine the activation of ERK1/2 MAP-kinase pathway and the release of pro-inflammatory mediators CXCL1, GM-CSF and MIF, known to be involved in the recruitment of circulating neutrophils and monocytes.	Nitrogen	33-34	mitogen-activated protein kinase 3	Homo sapiens	72-78
30785738-4	2019	(3) Decreased nitrogen levels reduced expressive abundance of PI3K, Class 3 PI3K, TSC2, and 4E-BP1 in monocultured IPEC-1, but 85% nitrogen level did not affect expressive abundance of PI3K, TSC2, mTORC1, 4E-BP1, and S6K1 in cocultured IPEC-1.	Nitrogen	14-22	TSC complex subunit 2	Sus scrofa	82-86
30742407-4	2019	The mechanical properties of the supramolecular thermosets can be systematically tailored by varying the ratios between Tri-PBA-PPG and Bi-PBA-PPG, which changes the cross-linking density of nitrogen-coordinated boroxines and the topology of the supramolecular thermosets.	Nitrogen	191-199	serglycin	Homo sapiens	128-131
31087998-16	2019	Fine root biomass and the soil carbon-nitrogen ratio were critical factors for variation of soil respiration under acid rain.	Nitrogen	38-46	Ras interacting protein 1	Homo sapiens	120-124
30949305-1	2019	Aldehyde Oxidase (AO) is an enzyme involved in the metabolism of aldehydes and N-containing heterocyclic compounds.	Nitrogen	79-80	aldehyde oxidase 1	Homo sapiens	0-16
30949305-1	2019	Aldehyde Oxidase (AO) is an enzyme involved in the metabolism of aldehydes and N-containing heterocyclic compounds.	Nitrogen	79-80	aldehyde oxidase 1	Homo sapiens	18-20
30742407-4	2019	The mechanical properties of the supramolecular thermosets can be systematically tailored by varying the ratios between Tri-PBA-PPG and Bi-PBA-PPG, which changes the cross-linking density of nitrogen-coordinated boroxines and the topology of the supramolecular thermosets.	Nitrogen	191-199	serglycin	Homo sapiens	143-146
30508798-3	2019	Based on the kinetic data, NO3- reduction and the selectivity for N2 highly depends on the ratio between Mg/Al, solution pH and sonication frequency.	Nitrogen	66-68	NBL1, DAN family BMP antagonist	Homo sapiens	27-30
30369550-8	2019	SNIPER(BRD)-3 contained an N-methylated LCL-161 derivative as the IAP ligand, which prevented it from binding IAPs, and resulted in the abrogated degradation of cIAP1, XIAP, and BRD4.	Nitrogen	1-2	bromodomain containing 4	Homo sapiens	178-182
30508798-9	2019	Without the use of consumable reducing agents (i.e. H2 gas), sonocatalytic reduction could be a potential candidate of remediation method to treat NO3- polluted water with high N2 selectivity and easy magnetic recovery.	Nitrogen	177-179	NBL1, DAN family BMP antagonist	Homo sapiens	147-150
31243177-10	2019	The opposite effects on nitrogen oxide synthase might provide an explanation, as the expression levels of nos2 gene are suppressed in the osteoclast but elevated in the osteoblast.	Nitrogen	24-32	nitric oxide synthase 2	Homo sapiens	106-110
31245758-7	2019	By enriching glycoproteins in gsnor1-3 and mass spectrometry analysis, TGG2 (thioglucoside glucohydrolase2) was identified as one of co-substrates with high degradation rate and elevated N-glycosylation level in gsnor1-3 ost3/6.	Nitrogen	187-188	GroES-like zinc-binding dehydrogenase family protein	Arabidopsis thaliana	30-36
30513349-7	2019	We were able to show that the N-linked glyco-structures of rhA1AT and rhC1INH are homogeneous and similar to the structures obtained from plasma-derived A1AT and C1INH, marketed as Prolastin -C and Cinryze , respectively.	Nitrogen	30-31	serpin family A member 1	Homo sapiens	61-65
30562194-6	2019	RESULTS: T/N ratios, fluctuations in ratio, and tumor volumes correlated significantly between ASL and C-met-PET at all time points and all periods.	Nitrogen	11-12	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	103-108
30685864-5	2019	Atmospheric sulfur and PM10 were efficiently put in control, but atmospheric nitrogen (NO2; precipitations of NO3- and NH4+) was increasing and posted a potential threat to air quality especially during 2011-2015.	Nitrogen	77-85	NBL1, DAN family BMP antagonist	Homo sapiens	110-113
30649293-3	2019	In C. albicans, Rhb1 regulates the expression of secreted protease 2, low nitrogen-mediated morphogenesis, and biofilm formation.	Nitrogen	74-82	putative GTPase RHB1	Saccharomyces cerevisiae S288C	16-20
30606520-1	2019	In this paper we describe a novel ultrasensitive electrochemiluminescent (ECL) aptasensor based on the quenching effect of aptamer and lysozyme incubation on co-reactant ECL mechanism of nitrogen-doped graphene quantum dots and persulfate.	Nitrogen	187-195	lysozyme	Homo sapiens	135-143
29498420-10	2019	This pioneering research demonstrates that genes in the BdNRT2 family have diverse roles, differing from the Arabidopsis AtNRT2 family, in response to various nitrogen conditions.	Nitrogen	159-167	nitrate transporter 2:1	Arabidopsis thaliana	121-127
31245758-8	2019	The S-nitrosylation and N-glycosylation profiles were also modified in dgl1-3 and gsnor1-3.	Nitrogen	24-25	GroES-like zinc-binding dehydrogenase family protein	Arabidopsis thaliana	82-88
30796533-11	2019	Graphical abstract Schematic presentation of the nitrogen and boron co-doped carbon dot-based fluorometric method for determination of alkaline phosphatase (ALP) activity.	Nitrogen	49-57	alkaline phosphatase, placental	Homo sapiens	135-155
29473769-2	2019	Aldehyde oxidase (AO enzymes)-mediated oxidation predominantly occurs at a carbon atom adjacent to the nitrogen on aromatic azaheterocycles.	Nitrogen	103-111	aldehyde oxidase 1	Homo sapiens	0-16
30796533-11	2019	Graphical abstract Schematic presentation of the nitrogen and boron co-doped carbon dot-based fluorometric method for determination of alkaline phosphatase (ALP) activity.	Nitrogen	49-57	alkaline phosphatase, placental	Homo sapiens	157-160
30620788-6	2019	Porous carbon tri-doped with nitrogen, phosphorous, and oxygen exhibits a high packing density (2.13 g cm-3 ) and an exceptional volumetric energy density (36.8 Wh L-1 ) in alkaline electrolytes, making it competitive to even some Ni-MH cells.	Nitrogen	29-37	immunoglobulin kappa variable 1-16	Homo sapiens	164-167
30689356-3	2019	Their kinetics were determined by monitoring the consumption of H2O2 with a nitrogen-doped carbon nanotubes (N-CNT) electrode, which could detect 0.50 muM H2O2 at -0.20 V. The unique design of internally calibrated electrochemical continuous enzyme assay (ICECEA) and electrode stability allowed use of one N-CNT electrode for over half a year to reliably determine MPO.	Nitrogen	76-84	myeloperoxidase	Homo sapiens	366-369
30508577-5	2019	In adults, this increased generation of reactive oxygen and nitrogen species (RONS) activate redox-sensitive transcription factors such as nuclear factor kappaB (NFkappaB), activator protein-1 (AP1) and heat shock factor 1 (HSF1), resulting in increases in cytoprotective proteins such as the superoxide dismutases, catalase and heat shock proteins that prevent oxidative damage to tissues and facilitate remodelling and proteostasis in both an intra- and inter-cellular manner.	Nitrogen	60-68	nuclear factor kappa B subunit 1	Homo sapiens	139-160
30508577-5	2019	In adults, this increased generation of reactive oxygen and nitrogen species (RONS) activate redox-sensitive transcription factors such as nuclear factor kappaB (NFkappaB), activator protein-1 (AP1) and heat shock factor 1 (HSF1), resulting in increases in cytoprotective proteins such as the superoxide dismutases, catalase and heat shock proteins that prevent oxidative damage to tissues and facilitate remodelling and proteostasis in both an intra- and inter-cellular manner.	Nitrogen	60-68	nuclear factor kappa B subunit 1	Homo sapiens	162-170
30508577-5	2019	In adults, this increased generation of reactive oxygen and nitrogen species (RONS) activate redox-sensitive transcription factors such as nuclear factor kappaB (NFkappaB), activator protein-1 (AP1) and heat shock factor 1 (HSF1), resulting in increases in cytoprotective proteins such as the superoxide dismutases, catalase and heat shock proteins that prevent oxidative damage to tissues and facilitate remodelling and proteostasis in both an intra- and inter-cellular manner.	Nitrogen	60-68	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	173-192
30508577-5	2019	In adults, this increased generation of reactive oxygen and nitrogen species (RONS) activate redox-sensitive transcription factors such as nuclear factor kappaB (NFkappaB), activator protein-1 (AP1) and heat shock factor 1 (HSF1), resulting in increases in cytoprotective proteins such as the superoxide dismutases, catalase and heat shock proteins that prevent oxidative damage to tissues and facilitate remodelling and proteostasis in both an intra- and inter-cellular manner.	Nitrogen	60-68	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	194-197
30380502-4	2019	The low total nitrogen (TN) removal efficiency was due to NO3--N accumulation and zeolite desorption.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
30720828-2	2019	Heating 2a-c in toluene leads to the liberation of one molecule of CpH to afford the corresponding N-bonded complexes [Cp2YbBp] (Bp = Bp1 (3a), Bp2 (3b), Bp3 (3c)).	Nitrogen	99-100	BP2	Homo sapiens	144-147
30721035-3	2019	Various peculiar nitrogen polymerization forms composed of single/double nitrogen-nitrogen bonds were found at the nitrogen-rich condition, such as N -chains in P21/ m-SeN3, oligomeric N8-chains in P1-SeN4, and distorted N63- anion rings in P1-SeN5.	Nitrogen	17-25	suppression of tumorigenicity 7	Homo sapiens	201-205
30645113-4	2019	Structure-activity relationship studies revealed that incorporation of a nitrogen atom into the phenothiazine framework results in increased potency and selectivity for HDAC6 (more than 500-fold selectivity relative to the inhibition of HDAC1, HDAC4, and HDAC8), as rationalized by molecular modeling and docking studies.	Nitrogen	73-81	histone deacetylase 4	Danio rerio	244-249
30335141-8	2019	Mass spectrometry analysis of patient sera also revealed an abnormal N-glycosylation profile for transferrin, a clinical diagnostic marker for congenital disorders of glycosylation.	Nitrogen	69-70	transferrin	Homo sapiens	97-108
30447563-4	2019	Carboxylic acids and phenol covered 88% of organic carbons while ammonia, NO2- and NO3- contributed for 73% of nitrogen.	Nitrogen	111-119	NBL1, DAN family BMP antagonist	Homo sapiens	83-86
30628347-6	2019	The results also suggested that 0.83 mg L-1NO3--N was consumed per 1 mg L-1 PO43--P removed during the denitrifying phosphorus removal, indicating that the simultaneous nitrogen and phosphorus removal was achieved in the ABR-MBR system.	Nitrogen	169-177	immunoglobulin kappa variable 1-16	Homo sapiens	40-43
30781796-7	2019	Removing all potential N-glycosylation sites from the C2V3 domain by site-specific mutagenesis reversed the vaccine-induced immune response towards a Th1-dominated T-cell response and a balanced IgG2a/IgG1 ratio.	Nitrogen	23-24	immunoglobulin heavy constant gamma 1 (G1m marker)	Mus musculus	201-205
30589515-3	2019	In colon adenocarcinomas, posttranslational modifications including O- and N- glycosylation of death receptors were found to correlate with TRAIL-induced apoptosis.	Nitrogen	75-76	TNF superfamily member 10	Homo sapiens	140-145
30605314-1	2019	Measurements of the stable isotope ratios of nitrogen (15N/14N) and oxygen (18O/16O) in nitrate (NO3-) enable identification of sources, dispersal, and fate of natural and contaminant NO3- in aquatic environments.	Nitrogen	45-53	NBL1, DAN family BMP antagonist	Homo sapiens	97-100
30390591-4	2019	In this setting, beta-CD cavities and positively charged N-containing groups of PEI were mainly responsible for removal of MO via host-guest inclusion and electrostatic attraction, respectively, and oxygen-bearing groups on the edge of beta-CD as well as the free amino moieties in PEI acted as the active sites for Pb(II) uptake.	Nitrogen	57-58	submaxillary gland androgen regulated protein 3B	Homo sapiens	316-322
30551041-2	2019	A 225-days operation demonstrated that the relatively low total nitrogen (TN) concentration of 6.56 mg/L in effluent could be achieved with influent NH4+-N and NO3--N both of 30 mg/L, resulting in a high TN removal of 89.1% at 17.5  C. Batch tests revealed that the NO3--N-to-NO2--N transformation ratio (NTR) of PD stabilized at 90% during the whole operation, which played a crucial role in the desirable performance.	Nitrogen	64-72	NBL1, DAN family BMP antagonist	Homo sapiens	160-163
30551041-2	2019	A 225-days operation demonstrated that the relatively low total nitrogen (TN) concentration of 6.56 mg/L in effluent could be achieved with influent NH4+-N and NO3--N both of 30 mg/L, resulting in a high TN removal of 89.1% at 17.5  C. Batch tests revealed that the NO3--N-to-NO2--N transformation ratio (NTR) of PD stabilized at 90% during the whole operation, which played a crucial role in the desirable performance.	Nitrogen	64-72	NBL1, DAN family BMP antagonist	Homo sapiens	266-269
30551041-2	2019	A 225-days operation demonstrated that the relatively low total nitrogen (TN) concentration of 6.56 mg/L in effluent could be achieved with influent NH4+-N and NO3--N both of 30 mg/L, resulting in a high TN removal of 89.1% at 17.5  C. Batch tests revealed that the NO3--N-to-NO2--N transformation ratio (NTR) of PD stabilized at 90% during the whole operation, which played a crucial role in the desirable performance.	Nitrogen	75-76	NBL1, DAN family BMP antagonist	Homo sapiens	160-163
30551041-2	2019	A 225-days operation demonstrated that the relatively low total nitrogen (TN) concentration of 6.56 mg/L in effluent could be achieved with influent NH4+-N and NO3--N both of 30 mg/L, resulting in a high TN removal of 89.1% at 17.5  C. Batch tests revealed that the NO3--N-to-NO2--N transformation ratio (NTR) of PD stabilized at 90% during the whole operation, which played a crucial role in the desirable performance.	Nitrogen	75-76	NBL1, DAN family BMP antagonist	Homo sapiens	266-269
30307768-4	2019	The goal of this study was to delineate the cellular pathway by which extracellular Mn2+ rescues N-glycosylation in TMEM165 knockout (KO) cells.	Nitrogen	97-98	transmembrane protein 165	Homo sapiens	116-123
30407574-0	2019	Overexpression of ATG8 in Arabidopsis Stimulates Autophagic Activity and Increases Nitrogen Remobilization Efficiency and Grain Filling.	Nitrogen	83-91	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	18-22
30471912-0	2019	Short communication: Milk urea nitrogen as a predictor of urinary nitrogen and urea nitrogen excretions of late-lactation dairy cows fed nitrogen-limiting diets.	Nitrogen	31-39	Weaning weight-maternal milk	Bos taurus	21-25
30471912-0	2019	Short communication: Milk urea nitrogen as a predictor of urinary nitrogen and urea nitrogen excretions of late-lactation dairy cows fed nitrogen-limiting diets.	Nitrogen	66-74	Weaning weight-maternal milk	Bos taurus	21-25
30471912-0	2019	Short communication: Milk urea nitrogen as a predictor of urinary nitrogen and urea nitrogen excretions of late-lactation dairy cows fed nitrogen-limiting diets.	Nitrogen	66-74	Weaning weight-maternal milk	Bos taurus	21-25
30471912-0	2019	Short communication: Milk urea nitrogen as a predictor of urinary nitrogen and urea nitrogen excretions of late-lactation dairy cows fed nitrogen-limiting diets.	Nitrogen	66-74	Weaning weight-maternal milk	Bos taurus	21-25
30407574-6	2019	More importantly, our data demonstrate that, when cultivated under full nitrate conditions, known to repress N remobilization due to sufficient N uptake from the soil, N remobilization efficiency can nevertheless be sharply and significantly increased by overexpressing ATG8 genomic sequences under the control of the ubiquitin promoter.	Nitrogen	109-110	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	270-274
30407574-6	2019	More importantly, our data demonstrate that, when cultivated under full nitrate conditions, known to repress N remobilization due to sufficient N uptake from the soil, N remobilization efficiency can nevertheless be sharply and significantly increased by overexpressing ATG8 genomic sequences under the control of the ubiquitin promoter.	Nitrogen	144-145	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	270-274
30308915-5	2019	Soil total nitrogen increased significantly when the dose of biochar exceeded 5 t ha-1, and the content of total nitrogen in the 40 t ha-1 biochar treatment increased each year.	Nitrogen	113-121	Rho GTPase activating protein 45	Homo sapiens	134-138
30585716-4	2019	Removing just one nitrogen linker between the Co(II)-binding bipyridine groups has a profound impact on the molecular geometry observed by single crystal analysis.	Nitrogen	18-26	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	46-52
30735303-6	2019	Meanwhile, the lowest COD/NH4 + -N ratio of ~2.0 in the HAR effluent ensured the lowest observed NO3 - -N/NH4 + -N ratio of ~14% in the nitritation-anammox reactor.	Nitrogen	26-27	NBL1, DAN family BMP antagonist	Homo sapiens	97-100
29742915-2	2019	Modulation of hexokinase activity and spatiotemporal location by reactive oxygen and nitrogen species as well as other gasotransmitters serves as the basis for a unique, underexplored method of tight and flexible regulation of these fundamental enzymes.	Nitrogen	85-93	hexokinase 1	Homo sapiens	14-24
29967251-2	2019	We hypothesized that inhibition of protein N-linked glycosylation, an endoplasmic reticulum co- and posttranslational modification crucial for RTK maturation and activation, could provide a new therapeutic approach for glioma radiosensitization.Experimental Design: We investigated the effects of a small-molecule inhibitor of the oligosaccharyltransferase (NGI-1) on EGFR family receptors, MET, PDGFR, and FGFR1.	Nitrogen	43-44	epidermal growth factor receptor	Homo sapiens	368-372
30658381-7	2019	As a target for antibody, GP5 possesses a conserved epitope flanked by N-glycosylation sites and hypervariable regions, a pattern of conserved epitopes shared by other viruses.	Nitrogen	71-72	glycoprotein V platelet	Homo sapiens	26-29
30552009-1	2019	A series of carbamate-based inhibitors of glutamate carboxypeptidase II (GCPII) were designed and synthesized using ZJ-43, N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]-l-glutamic acid, as a molecular template in order to better understand the impact of replacing one of the two nitrogen atoms in the urea-based GCPII inhibitor with an oxygen atom.	Nitrogen	283-291	folate hydrolase 1	Homo sapiens	42-71
30552009-1	2019	A series of carbamate-based inhibitors of glutamate carboxypeptidase II (GCPII) were designed and synthesized using ZJ-43, N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]-l-glutamic acid, as a molecular template in order to better understand the impact of replacing one of the two nitrogen atoms in the urea-based GCPII inhibitor with an oxygen atom.	Nitrogen	283-291	folate hydrolase 1	Homo sapiens	73-78
29967251-2	2019	We hypothesized that inhibition of protein N-linked glycosylation, an endoplasmic reticulum co- and posttranslational modification crucial for RTK maturation and activation, could provide a new therapeutic approach for glioma radiosensitization.Experimental Design: We investigated the effects of a small-molecule inhibitor of the oligosaccharyltransferase (NGI-1) on EGFR family receptors, MET, PDGFR, and FGFR1.	Nitrogen	43-44	platelet derived growth factor receptor beta	Homo sapiens	396-401
29967251-2	2019	We hypothesized that inhibition of protein N-linked glycosylation, an endoplasmic reticulum co- and posttranslational modification crucial for RTK maturation and activation, could provide a new therapeutic approach for glioma radiosensitization.Experimental Design: We investigated the effects of a small-molecule inhibitor of the oligosaccharyltransferase (NGI-1) on EGFR family receptors, MET, PDGFR, and FGFR1.	Nitrogen	43-44	fibroblast growth factor receptor 1	Homo sapiens	407-412
30121531-9	2019	At the end of monitoring, regardless of the arriving inflow load, the discharge presented stable concentrations of approximately 30 mg L-1, appearing to indicate that the limits for nitrogen elimination.	Nitrogen	182-190	immunoglobulin kappa variable 1-16	Homo sapiens	135-138
30461145-0	2019	A Nitrogen-Rich 2D sp2 -Carbon-Linked Conjugated Polymer Framework as a High-Performance Cathode for Lithium-Ion Batteries.	Nitrogen	2-10	Sp2 transcription factor	Homo sapiens	19-22
30543406-2	2019	Using a combination of experiments and high-fidelity molecular dynamics (MD) simulations, it is shown here that the hydrophilization of the sp2 carbon structure, induced by the presence of the C-N bonds, decreases the pure water permeance in CNNTs when compared with pristine and turbostratic carbon nanotubes (CNTs).	Nitrogen	195-196	Sp2 transcription factor	Homo sapiens	140-143
30634720-5	2019	The in vivo investigation showed that NGR1 treatment increased serum lipid, beta2-microglobulin, serum creatinine, and blood urea nitrogen levels of db/db mice.	Nitrogen	130-138	reticulon 4 receptor	Mus musculus	38-42
30461145-1	2019	A two-dimensional (2D) sp2 -carbon-linked conjugated polymer framework (2D CCP-HATN) has a nitrogen-doped skeleton, a periodical dual-pore structure and high chemical stability.	Nitrogen	91-99	Sp2 transcription factor	Homo sapiens	23-26
30687379-2	2018	A decrease in the yield and N content of the seeds was observed in the Arabidopsis SAG12 knockout mutants (sag12) relative to the wild type (Col0) under limited nitrogen nutrition.	Nitrogen	28-29	senescence-associated gene 12	Arabidopsis thaliana	83-88
30687379-2	2018	A decrease in the yield and N content of the seeds was observed in the Arabidopsis SAG12 knockout mutants (sag12) relative to the wild type (Col0) under limited nitrogen nutrition.	Nitrogen	161-169	senescence-associated gene 12	Arabidopsis thaliana	83-88
30628296-3	2019	When the ammonia concentration was low, the total nitrogen removal rate in the effluent decreased to 75.3%, the total nitrogen concentration in the effluent was~10 mg L-1, and excessive proliferation of the NOB was observed.	Nitrogen	118-126	immunoglobulin kappa variable 1-16	Homo sapiens	167-170
30628296-6	2019	When the ammonia concentration was low, the concentration of ammonia nitrogen in effluent was less than 1.0 mg L-1 and the total nitrogen concentration in the effluent was less than 6 mg L-1.	Nitrogen	69-77	immunoglobulin kappa variable 1-16	Homo sapiens	111-114
30628296-6	2019	When the ammonia concentration was low, the concentration of ammonia nitrogen in effluent was less than 1.0 mg L-1 and the total nitrogen concentration in the effluent was less than 6 mg L-1.	Nitrogen	129-137	immunoglobulin kappa variable 1-16	Homo sapiens	187-190
30312494-0	2019	Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10: a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients.	Nitrogen	56-57	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	20-26
30343578-3	2019	With sequential trypsin digestion of proteins, C18 depletion of peptides without glycosylation, PNGase F digestion of N-glycopeptides, PGC enrichment of N-glycans, CH3I permethylation of the enriched N-glycans, cell-surface N-glycomes of the HepG2 and LO2 cells were analyzed using C18-RPLC-MS/MS (HCD).	Nitrogen	97-98	progastricsin	Homo sapiens	135-138
30510114-6	2019	Through different approaches, we show that Psd1, the mitochondrial phosphatidylserine decarboxylase, is involved in mitophagy induction only after nitrogen starvation, whereas Psd2, which is located in vacuole, Golgi and endosome membranes, is required preferentially for mitophagy induction in the stationary phase of growth but also to a lesser extent for nitrogen starvation-induced mitophagy.	Nitrogen	358-366	phosphatidylserine decarboxylase 2	Saccharomyces cerevisiae S288C	176-180
30312494-11	2019	CONCLUSIONS: CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine ratio is significantly lower in Scandinavian carriers of CYP2D6*41 vs. CYP2D6*9-10.	Nitrogen	2-3	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	129-135
30312494-11	2019	CONCLUSIONS: CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine ratio is significantly lower in Scandinavian carriers of CYP2D6*41 vs. CYP2D6*9-10.	Nitrogen	2-3	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	129-135
30312494-0	2019	Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10: a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients.	Nitrogen	56-57	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	110-116
30312494-0	2019	Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10: a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients.	Nitrogen	56-57	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	110-116
30312494-0	2019	Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10: a study on therapeutic drug monitoring data from 1003 genotyped Scandinavian patients.	Nitrogen	56-57	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	110-116
30312494-11	2019	CONCLUSIONS: CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine ratio is significantly lower in Scandinavian carriers of CYP2D6*41 vs. CYP2D6*9-10.	Nitrogen	2-3	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	13-19
30767749-9	2019	CONCLUSION: In silico docking studies revealed that nitrogen-containing tetrahydro-pyridonaphthyridine and dihydro-pyridoquinazoline tricyclic lead scaffolds have emerged as novel PDE5A inhibitors for antihypertensive activity.	Nitrogen	52-60	phosphodiesterase 5A	Homo sapiens	180-185
31631785-5	2019	Furthermore, mutations that impaired the thiol reductase activity or disrupted the N-linked glycosylation, a posttranslational modification essential for its lysosomal localization, largely compromised GILT restriction of viral entry.	Nitrogen	83-84	IFI30 lysosomal thiol reductase	Homo sapiens	202-206
30172908-4	2019	The conserved features in known GILTs, such as signal peptide, CXXC motif, GILT signature sequence, N-glycosylation site and conserved cysteines, were all found in the putative PsGILT protein.	Nitrogen	100-101	gamma-interferon-inducible lysosomal thiol reductase	Pelodiscus sinensis	32-36
30172908-4	2019	The conserved features in known GILTs, such as signal peptide, CXXC motif, GILT signature sequence, N-glycosylation site and conserved cysteines, were all found in the putative PsGILT protein.	Nitrogen	100-101	gamma-interferon-inducible lysosomal thiol reductase	Pelodiscus sinensis	177-183
31606079-1	2019	N-terminal acetylation is a co- and post-translational modification catalyzed by the conserved N-terminal acetyltransferase (NAT) family of enzymes.	Nitrogen	0-1	N-alpha-acetyltransferase 15, NatA auxiliary subunit	Homo sapiens	95-123
28911270-4	2019	Stable PN was successfully achieved during the whole period with low effluent NO3-N concentration at less than 15 mg/L, due to effective suppression of nitrite-oxidizing bacteria activity at high concentrations of free ammonia (5.3-27.3 mg N/L) and low alkalinity-to-ammonia ratio.	Nitrogen	8-9	NBL1, DAN family BMP antagonist	Homo sapiens	78-81
30138037-6	2019	Here, we created a cardiomyocyte-specific Mgat1 knockout (KO) mouse to establish a model useful in exploring the relationship between hybrid/complex N-glycosylation and cardiac function and disease.	Nitrogen	149-150	mannoside acetylglucosaminyltransferase 1	Mus musculus	42-47
30703176-1	2019	AIMS: To elucidate the role of Link N in regulating inflammatory molecules from human mesenchymal stem cells (hMSCs) under interleukin (IL)-1beta stimulation in vitro and under Complete Freund"s Adjuvant (CFA)-induced arthritis of the temporomandibular joint (TMJ) in vivo.	Nitrogen	36-37	interleukin 1 beta	Homo sapiens	123-145
32422021-5	2019	The uncoupling of endothelial NO synthase (eNOS) and increased generation of free radicals in hyperglycemic conditions can also lead to the formation of highly reactive nitrogen species such as peroxynitrite, which can lead to DNA damage, carcinogenic mutations, and activation of critical pathways involved in cell proliferation and apoptosis.	Nitrogen	169-177	nitric oxide synthase 3	Homo sapiens	18-41
32422021-5	2019	The uncoupling of endothelial NO synthase (eNOS) and increased generation of free radicals in hyperglycemic conditions can also lead to the formation of highly reactive nitrogen species such as peroxynitrite, which can lead to DNA damage, carcinogenic mutations, and activation of critical pathways involved in cell proliferation and apoptosis.	Nitrogen	169-177	nitric oxide synthase 3	Homo sapiens	43-47
30327052-1	2019	Nitrogen-doped bamboo-shaped carbon nanotubes (N-BCNT) were synthesized from butylamine using the catalytic chemical vapor deposition (CCVD) process.	Nitrogen	0-8	craniofacial development protein 1	Homo sapiens	49-53
31606079-1	2019	N-terminal acetylation is a co- and post-translational modification catalyzed by the conserved N-terminal acetyltransferase (NAT) family of enzymes.	Nitrogen	0-1	N-alpha-acetyltransferase 15, NatA auxiliary subunit	Homo sapiens	125-128
30574022-0	2018	The role of N-glycosylation of CD200-CD200R1 interaction in classical microglial activation.	Nitrogen	12-13	CD200 receptor 1	Homo sapiens	37-44
30064106-6	2019	The results of nitrate isotopes indicated that NO3- mainly originated from soil organic nitrogen (SON), chemical fertilizer (CF), and manure and sewage wastes (M&amp;S).	Nitrogen	88-96	NBL1, DAN family BMP antagonist	Homo sapiens	47-50
30390510-10	2019	Our study implies that NO3- contamination in this area may become more severe in future with a lack of necessary controls and treatment for human-induced nitrogen sources.	Nitrogen	154-162	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
30390510-11	2019	Proposed approach is useful to understand how the NO3- contaminant behaves in large basin aquifer system under urban environments and might be applicable in other developing regions too because increasing populations may be associated with increasing nitrogen loadings.	Nitrogen	251-259	NBL1, DAN family BMP antagonist	Homo sapiens	50-53
30396103-1	2019	Nitrogen (N) removal in conventional bioretention systems is highly variable owing to the low nitrate (NO3-) elimination efficiency.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	103-106
30247550-2	2018	Genotoxic N-oxidized metabolites of PhIP react with the Cys34 of albumin (Alb) to form a sulfinamide adduct, a biomarker of the biologically effective dose.	Nitrogen	10-11	albumin	Homo sapiens	65-72
30247550-2	2018	Genotoxic N-oxidized metabolites of PhIP react with the Cys34 of albumin (Alb) to form a sulfinamide adduct, a biomarker of the biologically effective dose.	Nitrogen	10-11	albumin	Homo sapiens	74-77
30465670-1	2018	Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.	Nitrogen	24-25	catalase	Homo sapiens	128-136
30465670-1	2018	Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.	Nitrogen	24-25	catalase	Homo sapiens	138-141
30465670-1	2018	Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.	Nitrogen	24-25	superoxide dismutase 1	Homo sapiens	147-167
30465670-1	2018	Atomically dispersed Fe-N4 sites anchored on N-doped porous carbon materials (Fe-SAs/NC) can mimic two antioxidative enzymes of catalase (CAT) and superoxide dismutase (SOD), and therefore serves as a bifunctional single-atom-based enzyme (SAzyme) for scavenging reactive oxygen species (ROS) to remove excess ROS generated during oxidative stress in cells.	Nitrogen	24-25	superoxide dismutase 1	Homo sapiens	169-172
30574022-8	2018	Results: CD200R1 was N-glycosylated at Asparagine 44 (Asn44, N44).	Nitrogen	21-22	CD200 receptor 1	Homo sapiens	9-16
30574022-11	2018	The N-glycosylation of CD200R1 could serve as a therapeutic agent for CNS inflammation.	Nitrogen	4-5	CD200 receptor 1	Homo sapiens	23-30
30628403-4	2018	When the two-stage PN-ANAMMOX process was operated under NH4+-N-limited conditions, the "limit of technology" for nitrogen removal (TN&lt;3 mg L-1) could be easily achieved by following anoxic denitrification.	Nitrogen	114-122	immunoglobulin kappa variable 1-16	Homo sapiens	143-146
30025239-5	2018	Dissolved N2 in the river water ranged from 337 to 513 mumol N2 L-1, and dissolved N2O ranged from 10.4 to 15.4 nmol N2O L-1.	Nitrogen	10-12	L1 cell adhesion molecule	Homo sapiens	64-67
30743890-8	2018	Our approach provides time-dependent insight into nitrogen pollution in the studied aquifer over the past decades, revealing a systematic change in the dominant NO3- source, from agricultural to sewage contamination.	Nitrogen	50-58	NBL1, DAN family BMP antagonist	Homo sapiens	161-164
30495940-0	2018	Highly Green Emissive Nitrogen-Doped Carbon Dots with Excellent Thermal Stability for Bioimaging and Solid-State LED.	Nitrogen	22-30	small integral membrane protein 10 like 2A	Homo sapiens	113-116
30240135-2	2018	A cobalt@nitrogen-doped carbon (Co@NC) catalyst was prepared from renewable biomass-derived sucrose, harmless melamine, and earth-abundant Co(AcO)2 as the precursor materials by hydrothermal treatment and carbonization.	Nitrogen	9-17	aconitase 2	Homo sapiens	142-147
30290305-0	2018	Ablation of a Single N-Glycosylation Site in Human FSTL 1 Induces Cardiomyocyte Proliferation and Cardiac Regeneration.	Nitrogen	21-22	follistatin like 1	Homo sapiens	51-57
30628406-4	2018	When the NH4+-N and NO2--N concentrations were 450 mg L-1 and 560 mg L-1, respectively, the nitrogen removal was achieved in both the high-and low-substrate concentration reactors and the maximum NRR was 16.97 kg (m3 d)-1 and 14.43 kg (m3 d)-1, respectively.	Nitrogen	92-100	immunoglobulin kappa variable 1-16	Homo sapiens	54-72
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Nitrogen	54-62	CCDC26 long non-coding RNA	Homo sapiens	156-159
31949694-3	2018	A further sequence analysis found a novel PTCH1 INDEL mutation, NM_001083602.2: c.1516_1524delinsTGAGCTGGAGCTCCG (p. Ala506*), leading an N Terminal truncated protein.	Nitrogen	49-50	patched 1	Homo sapiens	42-47
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	48-63
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	65-68
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	88-94
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	113-119
30223124-3	2018	The required HRT to reach 98.5% COD removal was achieved at 7.5 h. Simultaneous CNP removal under denitrification rate of 199.4 mg/l.d gave high nitrate to nitrogen gas conversion of 74.6 mg/l.	Nitrogen	156-164	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	80-83
30358110-3	2018	Herein, the multifunctional polysulfide scavengers based on nitrogen, sulfur co-doped carbon cloth (DCC), which is supported by flower-like MoS2 (1T-2H) decorated with BaMn0.9 Mg0.1 O3 perovskite particle (PrNP) and carbon nanotubes (CNTs), namely, DCC@MoS2 /PrNP/CNTs, are delicately designed and synthesized.	Nitrogen	60-68	prion protein	Homo sapiens	206-210
30358110-3	2018	Herein, the multifunctional polysulfide scavengers based on nitrogen, sulfur co-doped carbon cloth (DCC), which is supported by flower-like MoS2 (1T-2H) decorated with BaMn0.9 Mg0.1 O3 perovskite particle (PrNP) and carbon nanotubes (CNTs), namely, DCC@MoS2 /PrNP/CNTs, are delicately designed and synthesized.	Nitrogen	60-68	prion protein	Homo sapiens	259-263
30282042-7	2018	However, their nitrogen oxidative derivatives produced by processing of Nux vomica, strychnine N-oxide and brucine N-oxide, lost their activity on hERG channels.	Nitrogen	15-23	ETS transcription factor ERG	Homo sapiens	147-151
30282042-8	2018	Compared to their parent compounds, only an oxygen atom was introduced in the nitrogen oxidative isoforms to compensate for the N+ - charge, suggesting that the protonated nitrogen is the key group for strychnine and brucine binding to hERG channel.	Nitrogen	78-86	ETS transcription factor ERG	Homo sapiens	236-240
30282042-8	2018	Compared to their parent compounds, only an oxygen atom was introduced in the nitrogen oxidative isoforms to compensate for the N+ - charge, suggesting that the protonated nitrogen is the key group for strychnine and brucine binding to hERG channel.	Nitrogen	172-180	ETS transcription factor ERG	Homo sapiens	236-240
30316685-2	2018	Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.	Nitrogen	185-193	CCDC26 long non-coding RNA	Homo sapiens	156-159
30383350-6	2018	The unique structure of nanosheets embedded by hollow carbon spheres and N-doping characteristics endow N-HMCS/S with good performance in electrochemical capacitor with high specific capacity (196.5 F g-1) in the three-electrode system and excellent high-rate capability with retention of 61.5% in the two-electrode system.	Nitrogen	73-74	MKKS centrosomal shuttling protein	Homo sapiens	106-110
30961222-7	2018	The most effective interaction and transfection activity into A549 cancer cells and silencing efficiency against vascular endothelial growth factor (VEGF) was found for a sample with average number of nitrogens in polyamine chain equal to 27, i.e., for a sample in which all grafted chains are longer than the critical length for polymeric amine-oligonucleotide complexation.	Nitrogen	201-210	vascular endothelial growth factor A	Homo sapiens	113-147
30961222-7	2018	The most effective interaction and transfection activity into A549 cancer cells and silencing efficiency against vascular endothelial growth factor (VEGF) was found for a sample with average number of nitrogens in polyamine chain equal to 27, i.e., for a sample in which all grafted chains are longer than the critical length for polymeric amine-oligonucleotide complexation.	Nitrogen	201-210	vascular endothelial growth factor A	Homo sapiens	149-153
30383350-6	2018	The unique structure of nanosheets embedded by hollow carbon spheres and N-doping characteristics endow N-HMCS/S with good performance in electrochemical capacitor with high specific capacity (196.5 F g-1) in the three-electrode system and excellent high-rate capability with retention of 61.5% in the two-electrode system.	Nitrogen	104-105	MKKS centrosomal shuttling protein	Homo sapiens	106-110
30379543-0	2018	Give and Take: A Watershed Acid Rain Mitigation Experiment Increases Baseflow Nitrogen Retention but Increases Stormflow Nitrogen Export.	Nitrogen	78-86	Ras interacting protein 1	Homo sapiens	32-36
30358987-9	2018	Nearly 2600 kg N y-1 was estimated to be removed through microbial gaseous N-production which equaled 72% of NO3--N and 60% of TN yearly retention in the wetland.	Nitrogen	0-1	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
30379543-0	2018	Give and Take: A Watershed Acid Rain Mitigation Experiment Increases Baseflow Nitrogen Retention but Increases Stormflow Nitrogen Export.	Nitrogen	121-129	Ras interacting protein 1	Homo sapiens	32-36
30355725-6	2018	We identify conserved N-glycosylated sites and describe the effect of mutating these residues on BMP pathway activity in Drosophila Functional analysis reveals that loss of individual Sog glycosylation sites enhances BMP antagonism and/or increases the spatial range of Sog effects in the tissue.	Nitrogen	22-23	short gastrulation	Drosophila melanogaster	184-187
30515097-4	2018	Clofazimine, but neither isoniazid nor rifampicin, caused dose-related potentiation of both ADP- and thrombin-activated expression of CD62P by platelets, achieving statistical significance at threshold concentrations of 0.625 and 2.5 mg/L, respectively, as well as significant formation of N:P aggregates.	Nitrogen	290-291	coagulation factor II, thrombin	Homo sapiens	101-109
29982029-7	2018	The Bi2S3@N-G/GC electrode demonstrated a wide concentration range for H2O2, from 10 to 42,960 muM, with a sensitivity of 0.1535 muA muM-1 and an obtained limit of detection of 1.9 muM.	Nitrogen	10-11	latexin	Homo sapiens	95-98
30450602-7	2018	IGFBP7 knockdown effectively alleviated the severity of the renal injury, evidenced by decreases in the urinary levels of creatinine, blood urea nitrogen, and albumin, cell apoptosis, and activation of ERK1/2 signaling in CLP mice.	Nitrogen	145-153	insulin-like growth factor binding protein 7	Mus musculus	0-6
30445747-1	2018	We have previously reported the synthesis, in vitro and in silico activities of new GABA analogues as inhibitors of the GABA-AT enzyme from Pseudomonas fluorescens, where the nitrogen atom at the gamma-position is embedded in heterocyclic scaffolds.	Nitrogen	175-183	4-aminobutyrate aminotransferase	Homo sapiens	120-127
29982029-7	2018	The Bi2S3@N-G/GC electrode demonstrated a wide concentration range for H2O2, from 10 to 42,960 muM, with a sensitivity of 0.1535 muA muM-1 and an obtained limit of detection of 1.9 muM.	Nitrogen	10-11	latexin	Homo sapiens	133-136
30085380-1	2018	RATIONALE: The stable nitrogen isotopic composition of nitrate (NO3 - ) can be an effective tool to identify NO3 - sources and understand nitrogen cycling.	Nitrogen	22-30	NBL1, DAN family BMP antagonist	Homo sapiens	64-67
30376013-3	2018	According to DFT studies, upon chelating a Zn2+ cation with two imidazole nitrogen atoms, receptor 1 adopts a conformation ideally fitted to recognise HSO4- through a combination of C(sp2)-HO and C(sp3)-HO hydrogen bondings, C+(sp2)-BrO halogen bonding and C(sp2)O tetrel bonding.	Nitrogen	74-82	Sp2 transcription factor	Homo sapiens	182-187
30085380-1	2018	RATIONALE: The stable nitrogen isotopic composition of nitrate (NO3 - ) can be an effective tool to identify NO3 - sources and understand nitrogen cycling.	Nitrogen	22-30	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
30085380-1	2018	RATIONALE: The stable nitrogen isotopic composition of nitrate (NO3 - ) can be an effective tool to identify NO3 - sources and understand nitrogen cycling.	Nitrogen	138-146	NBL1, DAN family BMP antagonist	Homo sapiens	64-67
30085380-2	2018	However, the usefulness of this isotopic tool in environment research has been limited by complex analytical procedures for the nitrogen isotopic analysis of NO3 - .	Nitrogen	128-136	NBL1, DAN family BMP antagonist	Homo sapiens	158-161
30085380-4	2018	METHODS: Water NO3 - was transformed into nitrobenzene for nitrogen isotopic analysis by gas chromatography-combustion-isotope ratio mass spectrometry (GC/C-IRMS).	Nitrogen	59-67	NBL1, DAN family BMP antagonist	Homo sapiens	15-18
30284450-3	2018	Herein, we demonstrate the use of LIG, created with a low-cost UV laser, for electrochemical ion-selective sensing of plant-available nitrogen (i.e., both ammonium and nitrate ions: NH4+ and NO3-) in soil samples.	Nitrogen	134-142	NBL1, DAN family BMP antagonist	Homo sapiens	191-194
30376013-3	2018	According to DFT studies, upon chelating a Zn2+ cation with two imidazole nitrogen atoms, receptor 1 adopts a conformation ideally fitted to recognise HSO4- through a combination of C(sp2)-HO and C(sp3)-HO hydrogen bondings, C+(sp2)-BrO halogen bonding and C(sp2)O tetrel bonding.	Nitrogen	74-82	Sp2 transcription factor	Homo sapiens	257-262
30628252-1	2018	The identification of the main inorganic nitrogen (MIN, referring to NH4+-N, NO3--N, and NO2--N) pollution sources in groundwater is of great significance to its control and repair.	Nitrogen	41-49	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
30398206-3	2018	The bond lengths in the central CNOS unit are 1.3444 (19), 1.3556 (18) and 1.6567 (15) A for C-N, C-O and C-S, respectively, and the CNOS and C3N moieties are flat and nearly coplanar with each other, consistent with the C-N bond possessing partial double-bond character.	Nitrogen	33-34	nitric oxide synthase 3	Homo sapiens	133-137
30222216-2	2018	The DOS distribution is tailored by embedding sp2 -nitrogen atoms into the donor moiety of the D-A backbone.	Nitrogen	51-59	Sp2 transcription factor	Homo sapiens	46-49
30398206-3	2018	The bond lengths in the central CNOS unit are 1.3444 (19), 1.3556 (18) and 1.6567 (15) A for C-N, C-O and C-S, respectively, and the CNOS and C3N moieties are flat and nearly coplanar with each other, consistent with the C-N bond possessing partial double-bond character.	Nitrogen	95-96	nitric oxide synthase 3	Homo sapiens	32-36
30391046-6	2018	Atmospheric N and S deposition, nitrification of soil N, and sulfide oxidation control the background levels of groundwater NO3- and SO42-.	Nitrogen	12-13	NBL1, DAN family BMP antagonist	Homo sapiens	124-127
30269161-3	2018	This N-CQD fluorescent probe has been successfully applied to selectively determine the concentration of copper ion (Cu2+) with a linear range of 0.1-40 muM and a limit of detection of 0.09 muM.	Nitrogen	5-6	latexin	Homo sapiens	153-156
30269161-3	2018	This N-CQD fluorescent probe has been successfully applied to selectively determine the concentration of copper ion (Cu2+) with a linear range of 0.1-40 muM and a limit of detection of 0.09 muM.	Nitrogen	5-6	latexin	Homo sapiens	190-193
30217930-7	2018	Moreover, PTEN or PI3K/AKT/mTOR signaling could affect DPAGT1, a glycosylating enzyme involved in the initial step of N-linked glycosylation, to inhibit glycosylation of NIS.	Nitrogen	13-14	solute carrier family 5 member 5	Homo sapiens	170-173
30051214-12	2018	The serum IL-6 level was associated with N-demethylation activity and tramadol tolerability.	Nitrogen	41-42	interleukin 6	Homo sapiens	10-14
29979471-5	2018	Both the anammox activity and its contribution to N2 production were sensitive to temporal variation and correlated well with the sediment NO3 - content.	Nitrogen	50-52	NBL1, DAN family BMP antagonist	Homo sapiens	139-142
29935808-5	2018	Nitrification might be one of the most important nitrogen transformation processes and groundwater intensely exploited was a major inducing factor for the NO3- pollution.	Nitrogen	49-57	NBL1, DAN family BMP antagonist	Homo sapiens	155-158
30391046-6	2018	Atmospheric N and S deposition, nitrification of soil N, and sulfide oxidation control the background levels of groundwater NO3- and SO42-.	Nitrogen	54-55	NBL1, DAN family BMP antagonist	Homo sapiens	124-127
30374089-0	2018	Arabidopsis NITROGEN LIMITATION ADAPTATION regulates ORE1 homeostasis during senescence induced by nitrogen deficiency.	Nitrogen	99-107	NAC domain containing protein 6	Arabidopsis thaliana	53-57
30156471-2	2018	Npr1 (nitrogen permease reactivator) is a downstream effector kinase of TORC1 that regulates the stability, activity, and trafficking of various nutrient permeases including the ammonium permeases Mep1, Mep2, and Mep3 and the general amino acid permease Gap1.	Nitrogen	6-14	natriuretic peptide receptor 1	Homo sapiens	0-4
30374089-6	2018	Our findings identified ORE1 as a downstream target of NLA/PHO2 (UBC24) and showed that post-translational regulation of ORE1 levels determines leaf senescence during nitrogen deficiency.	Nitrogen	167-175	NAC domain containing protein 6	Arabidopsis thaliana	24-28
30190419-3	2018	Older leaves of the Atxdh1 mutant exhibited early senescence, lower soluble protein, and lower organic N levels as compared with wild-type older leaves when grown with 1 mm nitrate but were comparable to the wild type under 5 mm nitrate.	Nitrogen	103-104	xanthine dehydrogenase 1	Arabidopsis thaliana	20-26
30374089-6	2018	Our findings identified ORE1 as a downstream target of NLA/PHO2 (UBC24) and showed that post-translational regulation of ORE1 levels determines leaf senescence during nitrogen deficiency.	Nitrogen	167-175	NAC domain containing protein 6	Arabidopsis thaliana	121-125
30190419-9	2018	Together, these results indicate that the absence of remobilized purine-degraded N from older leaves of Atxdh1 caused senescence symptoms, a result of higher chloroplastic protein degradation in older leaves of low-nitrate-grown plants.	Nitrogen	81-82	xanthine dehydrogenase 1	Arabidopsis thaliana	104-110
29288799-3	2018	Together with a recent finding that phytochrome B, one of photoreceptors, is activated in subterranean plant parts, the discovery that HY5 directly promotes the transcription of genes involved in nutrient uptake and utilisation, including several nitrogen and sulphur assimilation-related genes, expands our understanding of the ways in which light signalling effectively and co-ordinately modulates uptake and utilisation of multiple nutrients in plants.	Nitrogen	247-255	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	135-138
30086949-3	2018	The N-doped CNDs were applied as a multi-probe fluorescence quenching system to the sensitive detection of nitrite (NO2-), nitrate (NO3-) and ferric (Fe3+) ions in food matrices.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	132-135
30217835-4	2018	Exogenous Met induced the transcription of ARO8-2 and PDC but repressed the transcription of STR3, which is controlled by the putative MSN2 and GLN3 binding sites responding to nitrogen catabolite repression.	Nitrogen	177-185	cystathionine beta-lyase STR3	Saccharomyces cerevisiae S288C	93-97
30296068-0	2018	Comparative Site-Specific N-Glycosylation Analysis of Lactoperoxidase from Buffalo and Goat Milk Using RP-UHPLC-MS/MS Reveals a Distinct Glycan Pattern.	Nitrogen	26-27	lactoperoxidase	Capra hircus	54-69
30384496-5	2018	In other cases the anomeric effect facilitates SN1 and SN2 reactivity at the amide nitrogen.	Nitrogen	83-91	solute carrier family 38 member 3	Homo sapiens	47-50
30384496-5	2018	In other cases the anomeric effect facilitates SN1 and SN2 reactivity at the amide nitrogen.	Nitrogen	83-91	solute carrier family 38 member 5	Homo sapiens	55-58
30078634-1	2018	The oligosaccharyltransferase (OST) is a multisubunit enzyme complex that N-glycosylates proteins in the secretory pathway and is considered to be constitutive and unregulated.	Nitrogen	74-75	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	4-29
30374844-8	2018	TERF1 also regulates plant utilization of phosphorus (Pi) and nitrogen (N).	Nitrogen	62-70	ethylene-responsive transcription factor 1	Solanum lycopersicum	0-5
30373240-1	2018	Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable nitrogen in form of ammonium into cellular metabolism.	Nitrogen	60-68	glutamate-ammonia ligase	Homo sapiens	0-20
30373240-1	2018	Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable nitrogen in form of ammonium into cellular metabolism.	Nitrogen	124-132	glutamate-ammonia ligase	Homo sapiens	0-20
30078634-1	2018	The oligosaccharyltransferase (OST) is a multisubunit enzyme complex that N-glycosylates proteins in the secretory pathway and is considered to be constitutive and unregulated.	Nitrogen	74-75	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	31-34
30078634-2	2018	However, small-molecule OST inhibitors such as NGI-1 provide a pharmacological approach for regulating N-linked glycosylation.	Nitrogen	47-48	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	24-27
30025226-8	2018	Potential cytotoxicity and genotoxicity of the DBP mixtures were mainly attributed to the presence of nitrogen-containing DBPs and HAAs.	Nitrogen	102-110	D-box binding PAR bZIP transcription factor	Homo sapiens	47-50
30311906-6	2018	Using proteomic approaches, we identified that Srd5a3 loss affects a subset of glycoproteins with high N-glycans multiplicity per protein and decreased protein abundance or N-glycosylation level.	Nitrogen	103-104	steroid 5 alpha-reductase 3	Homo sapiens	47-53
30311906-7	2018	As IgSF-CAM adhesion proteins are critical for neuron adhesion and highly N-glycosylated, we observed impaired IgSF-CAM-mediated neurite outgrowth and axon guidance in Srd5a3 mutant cerebellum.	Nitrogen	74-75	calmodulin 3	Homo sapiens	8-11
30311906-7	2018	As IgSF-CAM adhesion proteins are critical for neuron adhesion and highly N-glycosylated, we observed impaired IgSF-CAM-mediated neurite outgrowth and axon guidance in Srd5a3 mutant cerebellum.	Nitrogen	74-75	calmodulin 3	Homo sapiens	116-119
30311906-7	2018	As IgSF-CAM adhesion proteins are critical for neuron adhesion and highly N-glycosylated, we observed impaired IgSF-CAM-mediated neurite outgrowth and axon guidance in Srd5a3 mutant cerebellum.	Nitrogen	74-75	steroid 5 alpha-reductase 3	Homo sapiens	168-174
30012463-5	2018	Among the potential corresponding target mRNAs for the selected mature miRNAs, seven cell growth-related target genes (e2f2, akt2, mtor, bcl-2, bim, p38alpha, and bmf) and five N-glycosylation-related target genes (neu1, b4galt3, gale, man1b1 and mgat4a) were selected by considering the effectiveness of NaBu on rCHO cell culture.	Nitrogen	43-44	BCL2, apoptosis regulator	Rattus norvegicus	137-142
30012463-5	2018	Among the potential corresponding target mRNAs for the selected mature miRNAs, seven cell growth-related target genes (e2f2, akt2, mtor, bcl-2, bim, p38alpha, and bmf) and five N-glycosylation-related target genes (neu1, b4galt3, gale, man1b1 and mgat4a) were selected by considering the effectiveness of NaBu on rCHO cell culture.	Nitrogen	43-44	mannosidase, alpha, class 1B, member 1	Rattus norvegicus	236-242
29807686-8	2018	With increasing Sfrp5 tertiles, the patients had higher frequencies of hypertension, stage 4 or 5 CKD, and waist-to-hip ratio, incrementally lower eGFRs and serum hemoglobin levels, and higher levels of blood urine nitrogen (BUN), creatinine, and adiponectin.	Nitrogen	215-223	secreted frizzled related protein 5	Homo sapiens	16-21
29860169-5	2018	In the following reactions, both theoretical calculation and experimental results reveal that the generated BP+  recovers itself to BP by grabbing an electron from NO3- and the generated nitrate radicals (NO3 ) then decay to nitrogen oxides.	Nitrogen	225-233	NBL1, DAN family BMP antagonist	Homo sapiens	164-167
29860169-5	2018	In the following reactions, both theoretical calculation and experimental results reveal that the generated BP+  recovers itself to BP by grabbing an electron from NO3- and the generated nitrate radicals (NO3 ) then decay to nitrogen oxides.	Nitrogen	225-233	NBL1, DAN family BMP antagonist	Homo sapiens	205-208
29981898-5	2018	Using an off-line HPLC-MALDI-TOF-MS approach combined with exoglycosidase digestions and MS/MS, we reveal that the multiple hexose residues of the N-glycans of the gly-12;gly-13;gly-14 triple mutant are not just mannose, but include galactoses in three different positions (beta-intersecting, beta-bisecting and alpha-terminal) on isomeric forms of Hex4-8HexNAc2 structures; some of these structures are fucosylated and/or methylated.	Nitrogen	147-148	GLYcosylation related	Caenorhabditis elegans	164-170
29886338-10	2018	The NO3- pollution in rivers was largely influenced by the irrigation regime, with a large amount of nitrogen in chemical fertilizer lost because of low utilization efficiency and subsequent transfer, via irrigation runoff, into the rivers.	Nitrogen	101-109	NBL1, DAN family BMP antagonist	Homo sapiens	4-7
29906753-1	2018	To exploit the advantages of less electron donor consumptions in partial-denitrification (denitratation, NO3-   NO2-) as well as less sludge production in autotrophic denitrification (AD) and anammox, a novel biological nitrogen removal (BNR) process through combined anammox and thiosulfate-driven denitratation was proposed here.	Nitrogen	220-228	NBL1, DAN family BMP antagonist	Homo sapiens	105-108
28845725-0	2018	Characterizing the in vitro species differences in N-glucuronidation of a potent pan-PIM inhibitor GNE-924 containing a 3,5-substituted 6-azaindazole.	Nitrogen	51-52	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	85-88
29982633-0	2018	SAG12, a Major Cysteine Protease Involved in Nitrogen Allocation during Senescence for Seed Production in Arabidopsis thaliana.	Nitrogen	45-53	senescence-associated gene 12	Arabidopsis thaliana	0-5
29982633-6	2018	Arabidopsis thaliana plants knocked-out for the SAG12 gene (sag12) did not exhibit any special phenotypic traits when grown under optimal nitrogen supply (HN), suggesting that other cysteine proteases could provide compensatory effects.	Nitrogen	138-146	senescence-associated gene 12	Arabidopsis thaliana	48-53
29982633-9	2018	Under low nitrogen (LN) availability, when inducible proteolytic systems are not sufficient to cope with SAG12 depletion, a decrease in yield is observed.	Nitrogen	10-18	senescence-associated gene 12	Arabidopsis thaliana	105-110
29913387-10	2018	After consideration of potential alternative sources (sewage, atmospheric deposition and groundwater) we concluded that there are three plausible interpretations for deviations from conservative mixing behaviour (1) NO3- uptake by assimilation (2) in situ NO3- production (from fixation-derived nitrogen and nitrification of sewage-derived effluents) and (3) input of groundwater nitrate carrying a denitrification signal.	Nitrogen	295-303	NBL1, DAN family BMP antagonist	Homo sapiens	256-259
29803190-2	2018	In addition, the concentration of NO3- in acid rain increases along with the rapid growth of nitrogen deposition.	Nitrogen	93-101	NBL1, DAN family BMP antagonist	Homo sapiens	34-37
30260937-7	2018	RESULTS Our study results showed that alpha1-AT level in TNBC tissues was higher than non-triple negative breast cancer (n-TNBC) and adjacent normal breast tissues.	Nitrogen	55-56	serpin family A member 1	Homo sapiens	38-47
30254341-7	2018	We conclude that an N fertilizer application rate of 240 kg ha-1 with mulch can achieve a relatively higher NTE, GY, WUE and NUE.	Nitrogen	20-21	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	60-64
30345292-7	2018	The accumulation of N-Hcy in hair keratin led to a progressive reduction of N-Hcy-keratin solubility in sodium dodecyl sulfate, from 0.39 +- 0.04 in wild-type mice to 0.19 +- 0.03, 0.14 +- 0.01, and 0.07 +- 0.03 in Mthfr -/-, Cse -/-, or Cbs -/-animals, respectively.	Nitrogen	20-21	methylenetetrahydrofolate reductase	Mus musculus	215-220
30179495-2	2018	The reaction constructs dual distinct C-N bonds via sp2/sp3 C-H activation and rhodium nitrene insertion.	Nitrogen	40-41	Sp2 transcription factor	Homo sapiens	52-55
30179495-2	2018	The reaction constructs dual distinct C-N bonds via sp2/sp3 C-H activation and rhodium nitrene insertion.	Nitrogen	40-41	Sp3 transcription factor	Homo sapiens	56-59
29906462-1	2018	The induction of bulk autophagy by nitrogen starvation in baker"s yeast (S. cerevisiae) involves the upregulation of many autophagy related proteins, including Atg7.	Nitrogen	35-43	Atg7p	Saccharomyces cerevisiae S288C	160-164
30283354-12	2018	Consistent with this SICM/FRET analysis demonstrated that beta2AR-cAMP was specifically reduced in t-tubules (TTs) after PMU (loaded TT 0.721 +- 0.106% vs. loaded crest 0.104 +- 0.062%, unloaded TT 0.112 +- 0.072% vs. unloaded crest 0.219 +- 0.084% N,n 5/6-9 mean +- SEM ** p &lt; 0.01, *** p &lt; 0.001 vs. loaded TT).	Nitrogen	249-250	cathelicidin antimicrobial peptide	Rattus norvegicus	58-70
30199257-2	2018	Aiming at obtaining compounds with improved multidrug-resistance (MDR) reversal activity, compound 8, an ent-abietane diterpene, was derivatized by introducing nitrogen-containing and aromatic moieties, yielding compounds 9-14.	Nitrogen	160-168	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	66-69
29776549-6	2018	Meanwhile, the sensor also shows a linear response to N2H4 in the range of 0.006-0.061 muM and 0.061-611.111 muM with a high sensitivity of 20.1 muA/muM cm2 in low concentration range as well as a very low LOD as 5.3 nM (S/N = 3).	Nitrogen	54-55	latexin	Homo sapiens	87-90
29776549-6	2018	Meanwhile, the sensor also shows a linear response to N2H4 in the range of 0.006-0.061 muM and 0.061-611.111 muM with a high sensitivity of 20.1 muA/muM cm2 in low concentration range as well as a very low LOD as 5.3 nM (S/N = 3).	Nitrogen	54-55	latexin	Homo sapiens	109-112
29776549-6	2018	Meanwhile, the sensor also shows a linear response to N2H4 in the range of 0.006-0.061 muM and 0.061-611.111 muM with a high sensitivity of 20.1 muA/muM cm2 in low concentration range as well as a very low LOD as 5.3 nM (S/N = 3).	Nitrogen	54-55	latexin	Homo sapiens	109-112
30271757-4	2018	Persistent inflammation causes ongoing production of large quantities of pro-inflammatory cytokines and both oxygen and nitrogen reactive species, with consequent activation of transcription factor nuclear factor-kappa B (NF-kappaB) and genes encoding for further production of pro-inflammatory cytokines, chemotactic factors, and growth factors.	Nitrogen	120-128	nuclear factor kappa B subunit 1	Homo sapiens	198-220
30271757-4	2018	Persistent inflammation causes ongoing production of large quantities of pro-inflammatory cytokines and both oxygen and nitrogen reactive species, with consequent activation of transcription factor nuclear factor-kappa B (NF-kappaB) and genes encoding for further production of pro-inflammatory cytokines, chemotactic factors, and growth factors.	Nitrogen	120-128	nuclear factor kappa B subunit 1	Homo sapiens	222-231
30028989-5	2018	N-ac(d-Ala2)GIP/GLP-1-exe significantly (P &lt; 0.001) stimulated insulin secretion from BRIN-BD11 cells and isolated mouse islets, and evoked dose-dependent increases (P &lt; 0.001) in cAMP production in both GIP-R and GLP-1-R transfected cells.	Nitrogen	0-2	gastric inhibitory polypeptide	Rattus norvegicus	12-15
29974791-3	2018	However, whether elevated levels of blood urea nitrogen are associated with increased risk of insulin use among people with diabetes is unknown.	Nitrogen	47-55	insulin	Homo sapiens	94-101
30107970-4	2018	In vitro studies showed that compounds 25-30 (20 muM) with N-methylation of the quinolone ring effectively inhibited Abeta1-42 aggregation by 84.7%-99.5% and tau aggregation by 71.2%-101.8%.	Nitrogen	59-60	latexin	Homo sapiens	49-52
30026325-3	2018	Here, we perform sensitivity screening of 94 lung cancer cell lines using NGI-1, a small-molecule inhibitor of the oligosaccharyltransferase (OST) that partially disrupts N-linked glycosylation, and demonstrate a selective loss of tumor cell viability.	Nitrogen	74-75	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	115-140
30026325-3	2018	Here, we perform sensitivity screening of 94 lung cancer cell lines using NGI-1, a small-molecule inhibitor of the oligosaccharyltransferase (OST) that partially disrupts N-linked glycosylation, and demonstrate a selective loss of tumor cell viability.	Nitrogen	74-75	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	142-145
30026325-7	2018	OST inhibition invariably disrupted EGFR N-linked glycosylation and reduced activation of receptors either with or without the T790M TKI resistance mutation.	Nitrogen	41-42	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	0-3
30026325-7	2018	OST inhibition invariably disrupted EGFR N-linked glycosylation and reduced activation of receptors either with or without the T790M TKI resistance mutation.	Nitrogen	41-42	epidermal growth factor receptor	Homo sapiens	36-40
30026325-10	2018	This therapeutic strategy breaks from kinase-targeted approaches and validates N-linked glycosylation as an effective target in tumors driven by glycoprotein signaling.Significance:EGFR-mutant NSCLC is incurable despite the marked sensitivity of these tumors to EGFR TKIs.	Nitrogen	79-80	epidermal growth factor receptor	Homo sapiens	181-185
30026325-11	2018	These findings identify N-linked glycosylation, a posttranslational modification common to EGFR and other oncogenic signaling proteins, as an effective therapeutic target that enhances tumor responses for EGFR-mutant NSCLC.	Nitrogen	24-25	epidermal growth factor receptor	Homo sapiens	91-95
30026325-11	2018	These findings identify N-linked glycosylation, a posttranslational modification common to EGFR and other oncogenic signaling proteins, as an effective therapeutic target that enhances tumor responses for EGFR-mutant NSCLC.	Nitrogen	24-25	epidermal growth factor receptor	Homo sapiens	205-209
29974791-5	2018	Spline analyses suggested that the relationship between blood urea nitrogen and the risk of insulin use was neutral below blood urea nitrogen level of 25 mg/dL and increased exponentially with blood urea nitrogen levels above 25 mg/dL.	Nitrogen	67-75	insulin	Homo sapiens	92-99
29974791-5	2018	Spline analyses suggested that the relationship between blood urea nitrogen and the risk of insulin use was neutral below blood urea nitrogen level of 25 mg/dL and increased exponentially with blood urea nitrogen levels above 25 mg/dL.	Nitrogen	133-141	insulin	Homo sapiens	92-99
29974791-5	2018	Spline analyses suggested that the relationship between blood urea nitrogen and the risk of insulin use was neutral below blood urea nitrogen level of 25 mg/dL and increased exponentially with blood urea nitrogen levels above 25 mg/dL.	Nitrogen	133-141	insulin	Homo sapiens	92-99
29974791-6	2018	In survival models, compared to those with blood urea nitrogen &lt;= 25 mg/dL, those with blood urea nitrogen &gt; 25 mg/dL had an increased risk of insulin use (hazard ratio = 1.40; confidence interval = 1.30-1.50).	Nitrogen	54-62	insulin	Homo sapiens	149-156
29974791-6	2018	In survival models, compared to those with blood urea nitrogen &lt;= 25 mg/dL, those with blood urea nitrogen &gt; 25 mg/dL had an increased risk of insulin use (hazard ratio = 1.40; confidence interval = 1.30-1.50).	Nitrogen	101-109	insulin	Homo sapiens	149-156
29974791-8	2018	Two-step residual estimation analyses showed that, independent of the impact of estimated glomerular filtration rate, every 10-mg/dL increase in blood urea nitrogen concentration was associated with increased risk of insulin use (hazard ratio = 1.16; confidence interval = 1.12-1.20).	Nitrogen	156-164	insulin	Homo sapiens	217-224
29974791-9	2018	Our results suggest that, among people with diabetes, higher levels of blood urea nitrogen are associated with an increased risk of insulin use.	Nitrogen	82-90	insulin	Homo sapiens	132-139
30198004-0	2018	Altering Nitrogen Heterocycles of AZD2461 Affords High Affinity Poly(ADP-ribose) Polymerase-1 Inhibitors with Decreased P-Glycoprotein Interactions.	Nitrogen	9-17	ATP binding cassette subfamily B member 1	Homo sapiens	120-134
29853097-4	2018	Nitrogen adsorption/desorption analysis confirmed mesoporous structure of Cb-D-MSN and Cb-L-MSN.	Nitrogen	0-8	moesin	Homo sapiens	79-82
29853097-4	2018	Nitrogen adsorption/desorption analysis confirmed mesoporous structure of Cb-D-MSN and Cb-L-MSN.	Nitrogen	0-8	moesin	Homo sapiens	92-95
30157178-9	2018	The ability of the MGAT1- CHO cell line to limit glycosylation to early intermediates in the N-linked glycosylation pathway without impairing the doubling time or ability to grow at high cell densities suggests that it will be a useful substrate for the biopharmaceutical production of HIV-1 vaccine immunogens.	Nitrogen	93-94	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Cricetulus griseus	19-24
30067011-7	2018	Consequently, SIM and N-siRNA synergistically increased the BMP-2/noggin ratio and resulted in an obviously higher osteogenetic effect than did simvastatin or N-siRNA alone, both in vitro and in vivo.	Nitrogen	22-23	bone morphogenetic protein 2	Mus musculus	60-65
30143874-0	2018	Electrochemiluminescent aptasensor for thrombin using nitrogen-doped graphene quantum dots.	Nitrogen	54-62	coagulation factor II, thrombin	Homo sapiens	39-47
30186302-6	2018	PH-treated plants grown with lower N availability showed reduced expression of NR and NiR as well as of nitrate and ammonium transporter transcripts in both leaf and root tissues in comparison with untreated plants; this was especially pronounced after application of PH by substrate drench.	Nitrogen	35-36	nitrate reductase [NADH]	Solanum lycopersicum	79-81
31459117-0	2018	Nitrogen-Doped Nanoporous Carbon Nanospheroids for Selective Dye Adsorption and Pb(II) Ion Removal from Waste Water.	Nitrogen	0-8	submaxillary gland androgen regulated protein 3B	Homo sapiens	80-86
31459117-4	2018	The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively.	Nitrogen	145-153	Sp2 transcription factor	Homo sapiens	107-110
31459117-4	2018	The X-ray photoelectron spectroscopy study shows the binding energies of 398.33 and 400.7 eV attributed to sp2 (C-N=C)- and sp3 (C-N)-hybridized nitrogen-bonded carbons, respectively.	Nitrogen	145-153	Sp3 transcription factor	Homo sapiens	124-127
30960859-9	2018	In the series of Co(II)/AlEt2Cl binary systems, complexes containing electron-withdrawing N-aryl substituents (R = 4-CF3, 2,6-2F) afforded higher molecular weights polyisoprene than that was obtained by the complex containing electron-donating N-alkyl substituents (R = octyl).	Nitrogen	90-91	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	17-23
30091755-2	2018	The key step in the assembly of the complex ring system of the target molecules is a photoredox catalytic nitrogen-centered radical cascade reaction, which allows the regioselective and stereoselective construction of the B, C, and D rings and the installation of the C21 chirality of the eburnane alkaloid skeleton in one pot.	Nitrogen	106-114	TBL1X/Y related 1	Homo sapiens	268-271
30074595-3	2018	In the other, a transient IDipp (1,3-di(2,6-diisopropylphenyl)imidazol-2-ylidene) adduct of MesBNtBu undergoes a shift of one carbene-bound Dipp substituent to the iminoborane nitrogen atom, yielding (1-Dipp-imidazol-2-yl)(Mes)B-N(Dipp)(tBu).	Nitrogen	176-184	nudix hydrolase 3	Homo sapiens	27-31
30131559-1	2018	Recombinant production of glycoprotein therapeutics like erythropoietin (EPO) in mammalian CHO cells rely on the heterogeneous N-glycosylation capacity of the cell.	Nitrogen	127-128	erythropoietin	Homo sapiens	57-71
30131559-1	2018	Recombinant production of glycoprotein therapeutics like erythropoietin (EPO) in mammalian CHO cells rely on the heterogeneous N-glycosylation capacity of the cell.	Nitrogen	127-128	erythropoietin	Homo sapiens	73-76
30074595-3	2018	In the other, a transient IDipp (1,3-di(2,6-diisopropylphenyl)imidazol-2-ylidene) adduct of MesBNtBu undergoes a shift of one carbene-bound Dipp substituent to the iminoborane nitrogen atom, yielding (1-Dipp-imidazol-2-yl)(Mes)B-N(Dipp)(tBu).	Nitrogen	176-184	nudix hydrolase 3	Homo sapiens	140-144
30074595-3	2018	In the other, a transient IDipp (1,3-di(2,6-diisopropylphenyl)imidazol-2-ylidene) adduct of MesBNtBu undergoes a shift of one carbene-bound Dipp substituent to the iminoborane nitrogen atom, yielding (1-Dipp-imidazol-2-yl)(Mes)B-N(Dipp)(tBu).	Nitrogen	176-184	nudix hydrolase 3	Homo sapiens	140-144
30103455-1	2018	Glutamine synthetase (GS) plays a key role in nitrogen metabolism.	Nitrogen	46-54	glutamine synthetase	Nicotiana tabacum	0-20
29873769-3	2018	The role of the different Arabidopsis GS1 isoforms in nitrogen remobilization was examined using 15N tracing experiments.	Nitrogen	54-62	Haloacid dehalogenase-like hydrolase (HAD) superfamily protein	Arabidopsis thaliana	38-41
29945795-3	2018	Selective JAK1/2 inhibitor, ruxolitinib (3), and pan-HDAC inhibitor vorinostat (4) were linked together by a single nitrogen atom to create a new series of compounds with very potent JAK2 and HDAC6 inhibition with selectivity against HDAC1.	Nitrogen	116-124	Janus kinase 1	Homo sapiens	10-16
29949713-6	2018	Sulfatase and leucine-aminopeptidase activities (linked to the sulfur and nitrogen cycles) were the most sensitive to Ag.	Nitrogen	74-82	arylsulfatase family member H	Homo sapiens	0-9
29998700-8	2018	RDA analysis showed that soil carbon and nitrogen contents had significant positive relationships with the activities of BG and NAG in the 0-20 cm soil profiles, however, negative relationships were observed in the 20-40 cm soil profiles.	Nitrogen	41-49	N-acetyl-alpha-glucosaminidase	Homo sapiens	128-131
29998685-4	2018	The nitrogen removal efficiency of the PN/A double-bacteria-layer system remained stable at~80% when the influent NH4+-N was 200 mg L-1 or 400 mg L-1 in the presence of 1.0 mg L-1 DO, whereas those of the control group were only 58.1% and 61.4%, respectively.	Nitrogen	4-12	immunoglobulin kappa variable 1-16	Homo sapiens	146-149
29998685-4	2018	The nitrogen removal efficiency of the PN/A double-bacteria-layer system remained stable at~80% when the influent NH4+-N was 200 mg L-1 or 400 mg L-1 in the presence of 1.0 mg L-1 DO, whereas those of the control group were only 58.1% and 61.4%, respectively.	Nitrogen	4-12	immunoglobulin kappa variable 1-16	Homo sapiens	146-149
29709805-4	2018	Furthermore, the nitrogen removal efficiency (NRE) decreased to 82.02 +- 3.14% when COD was increased to 730 +- 9 mg L-1, and effluent free ammonia (FA) reached 21.93 +- 4.71 mg L-1 might be one of factors leading to inhibition.	Nitrogen	17-25	immunoglobulin kappa variable 1-16	Homo sapiens	117-120
30027966-4	2018	Therefore, the nitrogen doping in the sp2 carbon network can be controlled by the flow rate of the C/N feedstock.	Nitrogen	15-23	Sp2 transcription factor	Homo sapiens	38-41
31458983-6	2018	A high uptake of CO2 (up to 5.27 mmol/g at 0  C and 1 bar) and high CO2-over-N2 and CO2-over-CH4 selectivities were observed.	Nitrogen	77-79	solute carrier family 6 member 1	Homo sapiens	38-53
29972295-6	2018	At the same time, we were able to partially resolve linkage isoforms of the fucosylated glycoforms and to identify and quantify SHBG N-glycoforms that were not previously reported.	Nitrogen	133-134	sex hormone binding globulin	Homo sapiens	128-132
30076387-1	2018	Glutamine synthetase (GS) is an enzyme that regulates nitrogen metabolism and synthesizes glutamine via glutamate, ATP, and ammonia.	Nitrogen	54-62	glutamate-ammonia ligase	Homo sapiens	0-20
29704850-7	2018	The NH4+/NO3- experiment result demonstrated that ammonia and nitrate did convert into N2 during SCWO, however, the formation of N2 was little without auxiliary fuel.	Nitrogen	87-89	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
29704850-7	2018	The NH4+/NO3- experiment result demonstrated that ammonia and nitrate did convert into N2 during SCWO, however, the formation of N2 was little without auxiliary fuel.	Nitrogen	129-131	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
29709805-3	2018	Efficient nitrogen removal was realized because denitrifying bacteria and anammox bacteria (AnAOB) had a better synergistic effect under the condition of chemical oxygen demand (COD) concentrations lower than 251 +- 7 mg L-1.	Nitrogen	10-18	immunoglobulin kappa variable 1-16	Homo sapiens	221-224
29709805-4	2018	Furthermore, the nitrogen removal efficiency (NRE) decreased to 82.02 +- 3.14% when COD was increased to 730 +- 9 mg L-1, and effluent free ammonia (FA) reached 21.93 +- 4.71 mg L-1 might be one of factors leading to inhibition.	Nitrogen	17-25	immunoglobulin kappa variable 1-16	Homo sapiens	178-181
29709805-5	2018	However, the nitrogen-removal contribution rate of anammox remained steady at 61.97 +- 2.84% at COD of 730 +- 9 mg L-1, which indicated that anammox was still dominant in the system.	Nitrogen	13-21	immunoglobulin kappa variable 1-16	Homo sapiens	115-118
29458646-3	2018	The ideal selectivity for CO2/N2 was 32.5 with a CO2 permeance of 57.1 GPU when CdO 4 liquid.	Nitrogen	30-32	cell adhesion associated, oncogene regulated	Homo sapiens	80-83
29717387-0	2018	beta4GalT1 Mediates PPARgamma N-Glycosylation to Attenuate Microglia Inflammatory Activation.	Nitrogen	30-31	peroxisome proliferator activated receptor gamma	Homo sapiens	20-29
29717387-4	2018	In this study, the N-glycosylation of PPARgamma, as well as two N-linked glycosylation sites in its DNA binding domain (DBD), was identified.	Nitrogen	19-20	peroxisome proliferator activated receptor gamma	Homo sapiens	38-47
29717387-5	2018	Disruption of both sites by site-directed mutagenesis completely abrogated the N-glycosylation of PPARgamma.	Nitrogen	79-80	peroxisome proliferator activated receptor gamma	Homo sapiens	98-107
29631126-5	2018	Only one compound (the dimethylisoxazole SGC-CBP30; a selective inhibitor of CREBBP (CBP) and EP300 bromodomains) is also predicted to have a salt-bridge between the morpholine nitrogen and Glu1389.	Nitrogen	177-185	sarcoglycan beta	Homo sapiens	41-44
27834049-9	2018	Biofilm community characteristics (C/N ratio) may also be an influential determinant of PFAS bioaccumulation.	Nitrogen	37-38	phosphoribosylformylglycinamidine synthase	Homo sapiens	88-92
29524892-4	2018	The results of isotopic tracing and microbial diversity analysis indicated that NH4+ was first oxidized to NO2- by Fe(III), then NO3- was reduced to NO2- and N2 by the Fe(II) produced in Feammox process, and finally, the NO2- produced in NAFO process underwent an Anammox process with the remaining NH4+ to yield N2.	Nitrogen	158-160	NBL1, DAN family BMP antagonist	Homo sapiens	129-132
29524892-4	2018	The results of isotopic tracing and microbial diversity analysis indicated that NH4+ was first oxidized to NO2- by Fe(III), then NO3- was reduced to NO2- and N2 by the Fe(II) produced in Feammox process, and finally, the NO2- produced in NAFO process underwent an Anammox process with the remaining NH4+ to yield N2.	Nitrogen	313-315	NBL1, DAN family BMP antagonist	Homo sapiens	129-132
29728002-0	2018	Interfacial growth of nitrogen-doped carbon with multi-functional groups on the MoS2 skeleton for efficient Pb(II) removal.	Nitrogen	22-30	submaxillary gland androgen regulated protein 3B	Homo sapiens	108-114
30087611-6	2018	Inhibition studies using human liver microsomes showed that CYP3A4, 2B6, and 2C9 together contributed 19.0 +- 2.6% (mean +- 95%CI) to O-demethylation, 4.0 +- 0.7% to alpha-hydroxylation, and 7.6 +- 1.7% to N-dealkylation of metoprolol.	Nitrogen	206-207	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	60-71
29920200-4	2018	Ab initio calculations explain the extraordinarily strong Ir cluster binding through selective sp3 rehybridization of boron nitride involving B-Ir cluster bonds and a strengthening of the nitrogen bonds to the Ir substrate in a specific, initially only chemisorbed valley area within the moire.	Nitrogen	188-196	Sp3 transcription factor	Homo sapiens	95-98
30182584-6	2018	The results showed that higher levels of N addition significantly decreased dehydrogenase (DHA) and beta-1,4-N-acetylglucosaminidase (NAG) activities by 22.3% and 12.5%, respectively.	Nitrogen	41-42	N-acetyl-alpha-glucosaminidase	Homo sapiens	100-132
30182584-6	2018	The results showed that higher levels of N addition significantly decreased dehydrogenase (DHA) and beta-1,4-N-acetylglucosaminidase (NAG) activities by 22.3% and 12.5%, respectively.	Nitrogen	41-42	N-acetyl-alpha-glucosaminidase	Homo sapiens	134-137
29680701-3	2018	Cubic Au@Pt dendritic nanomaterials functionalized nitrogen-doped graphene loaded with copper ion (Au@Pt DNs/NG/Cu2+) with enhanced peroxidase-like properties was synthesized as labels to effectively capture and immobilize secondary anti-CEA.	Nitrogen	51-59	CEA cell adhesion molecule 3	Homo sapiens	238-241
30052682-4	2018	Here, we report the identification of F-box only protein 2 (FBXO2), an SCF ubiquitin ligase substrate adaptor that preferentially binds high-mannose glycans and attenuates EBV infectivity by targeting N-glycosylated gB for degradation.	Nitrogen	201-202	F-box protein 2	Homo sapiens	60-65
30009313-0	2018	Binding indirect greenhouse gases OCS and CS2 by nitrogen heterocyclic carbenes (NHCs).	Nitrogen	49-57	chorionic somatomammotropin hormone 2	Homo sapiens	42-45
30030497-5	2018	Using a mouse model of angiotensin II (Ang II)-induced renal damage, we demonstrate that PI3Kgamma inhibitor AS605240 effectively mitigates Ang II-induced increases in serum creatinine and blood urea nitrogen, renal interstitial collagen deposition, the accumulation of ECM proteins and the expression of alpha-Sma and fibrosis-related genes in vivo.	Nitrogen	200-208	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	140-146
30041403-8	2018	Finally, 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide (MTT) assays showed that Neuroglobin is an important neuroprotectant that protects SK-N-SH cells from TNF-alpha-induced decrease in cell viability.	Nitrogen	95-96	tumor necrosis factor	Homo sapiens	172-181
29769321-4	2018	Here, to investigate both mechanisms of IAV neutralization in greater detail, we produced an N-glycosylated neck-CRD fragment of porcine SP-D (RpNCRD) in HEK293 cells.	Nitrogen	93-94	surfactant protein D	Sus scrofa	137-141
29962160-5	2018	There were significant negative correlations between catalase and the ratio of soil carbon and nitrogen, and urease was positively correlated to total nitrogen and soil moisture.	Nitrogen	95-103	catalase	Homo sapiens	53-61
29962164-7	2018	The order of importance was phosphatase activity &gt; pH &gt; sucrase activity &gt; catalase activity &gt; total N &gt; available P &gt; available K &gt; soil moisture content &gt; urease activity &gt; electrical conductivity (EC); phosphatase activity, pH value, invertase activity, catalase activity, total nitrogen, available phosphorus, and available potassium showed significant correlation with SOC and SIC (P&lt;0.01).	Nitrogen	309-317	catalase isozyme 1-like	Gossypium hirsutum	84-92
30021972-2	2018	A nitrogen-rich polymer of an intrinsic microporosity (PIM) precursor is impregnated with PtCl62- to give (after vacuum carbonization at 700  C) a nitrogen-containing heterocarbon with embedded Pt nanoparticles of typically 1-4 nm diameter (with some particles up to 20 nm diameter).	Nitrogen	2-10	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	55-58
30021972-2	2018	A nitrogen-rich polymer of an intrinsic microporosity (PIM) precursor is impregnated with PtCl62- to give (after vacuum carbonization at 700  C) a nitrogen-containing heterocarbon with embedded Pt nanoparticles of typically 1-4 nm diameter (with some particles up to 20 nm diameter).	Nitrogen	147-155	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	55-58
30093945-9	2018	In kidney, the expressions of tubular injury markers of kidney injury molecule-1 (KIM-1) and gelatinase-associated lipocalin (NGAL) were further upregulated along with higher levels of blood urea nitrogen (BUN), creatinine (Cr), and MDA in celastrol-treated mice.	Nitrogen	196-204	hepatitis A virus cellular receptor 1	Mus musculus	56-80
30093945-9	2018	In kidney, the expressions of tubular injury markers of kidney injury molecule-1 (KIM-1) and gelatinase-associated lipocalin (NGAL) were further upregulated along with higher levels of blood urea nitrogen (BUN), creatinine (Cr), and MDA in celastrol-treated mice.	Nitrogen	196-204	hepatitis A virus cellular receptor 1	Mus musculus	82-87
29701898-1	2018	Pentazolate anion (cyclo-N5- ), and/or N3- , NO3- were used as the ligands to obtain a series of nitrogen-rich energetic three-dimensional (3D) frameworks [Cu(N5 )(N3 )]n , [Ag(N5 )]n , [Ba(N5 )(NO3 )(H2 O)3 ]n , and [NaBa3 (N5 )6 (NO3 )(H2 O)3 ]n by self-assembly.	Nitrogen	97-105	NBL1, DAN family BMP antagonist	Homo sapiens	45-48
29701898-1	2018	Pentazolate anion (cyclo-N5- ), and/or N3- , NO3- were used as the ligands to obtain a series of nitrogen-rich energetic three-dimensional (3D) frameworks [Cu(N5 )(N3 )]n , [Ag(N5 )]n , [Ba(N5 )(NO3 )(H2 O)3 ]n , and [NaBa3 (N5 )6 (NO3 )(H2 O)3 ]n by self-assembly.	Nitrogen	97-105	NBL1, DAN family BMP antagonist	Homo sapiens	195-198
29701898-1	2018	Pentazolate anion (cyclo-N5- ), and/or N3- , NO3- were used as the ligands to obtain a series of nitrogen-rich energetic three-dimensional (3D) frameworks [Cu(N5 )(N3 )]n , [Ag(N5 )]n , [Ba(N5 )(NO3 )(H2 O)3 ]n , and [NaBa3 (N5 )6 (NO3 )(H2 O)3 ]n by self-assembly.	Nitrogen	97-105	NBL1, DAN family BMP antagonist	Homo sapiens	195-198
29691238-7	2018	These findings revealed that the methyl group at the N-14 atom of these analogs and their pharmacokinetic behaviors were the main determinants for AHR activation, and suggest that attention should be given to monitoring bile acid metabolism in the clinical use of E. rutaecarpa.	Nitrogen	53-54	aryl-hydrocarbon receptor	Mus musculus	147-150
30310585-3	2018	Herein, we report the synthesis of a novel redox active ligand, [ibaps]3-, which binds to transition metals such as FeII and CoII in a meridional fashion through the three anionic nitrogen atoms and provides additional coordination sites for other ligands.	Nitrogen	180-188	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	125-129
30027888-6	2018	All three trans-acting sRNAs are under direct transcriptional control of global nitrogen regulators and affect expression of components of nitrogen metabolism (glutamine synthetase, nitrogenase, and PII-like proteins) by either masking the ribosome binding site and thus inhibiting translation initiation or stabilizing the respective target mRNAs.	Nitrogen	139-147	glutamate-ammonia ligase	Homo sapiens	160-180
29724783-10	2018	The expression of Elovl4 and Fa2h thus correlate with the abundance of n-Vs and h-Vs in the SLs of rat spermatocytes and spermatids, respectively.	Nitrogen	13-14	ELOVL fatty acid elongase 4	Rattus norvegicus	18-24
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	retinoic acid receptor RXR-alpha	Capra hircus	190-215
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	retinoic acid receptor RXR-alpha	Capra hircus	217-225
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	klotho	Capra hircus	251-257
29754009-10	2018	From these data, it can be concluded that the downregulation of renal CYP27B1 expression observed with dietary N reduction is probably mediated by a complex interaction between the somatotropic axis and the Klotho/FGF signaling pathway in young goats.	Nitrogen	111-112	klotho	Capra hircus	207-213
28875725-3	2018	The aim of this study was to determine the association between the maternal interleukin-1beta (IL-1beta) haplotype and expression variation with oxides of nitrogen (NOx) levels, and thereafter investigate the IL-1beta haplotype-specific effects of NOx exposure levels, IL-1beta mRNA expression and other variables on gestational age.	Nitrogen	155-163	interleukin 1 beta	Homo sapiens	76-93
28875725-3	2018	The aim of this study was to determine the association between the maternal interleukin-1beta (IL-1beta) haplotype and expression variation with oxides of nitrogen (NOx) levels, and thereafter investigate the IL-1beta haplotype-specific effects of NOx exposure levels, IL-1beta mRNA expression and other variables on gestational age.	Nitrogen	155-163	interleukin 1 beta	Homo sapiens	95-103
29939992-8	2018	Overexpression of KCS1, which promotes formation of inositol pyrophosphates, is sufficient to drive pseudohyphal filamentation on medium with normal nitrogen levels.	Nitrogen	149-157	inositol polyphosphate kinase KCS1	Saccharomyces cerevisiae S288C	18-22
29971053-0	2018	Phospholipolysis Caused by Different Types of Bacterial Phospholipases During Cold Storage of Bovine Raw Milk Is Prevented by N2 Gas Flushing.	Nitrogen	126-128	Weaning weight-maternal milk	Bos taurus	105-109
29868651-1	2018	Balancing N2 displacement and N2 functionalization in the reaction of coordinated N2 with CS2.	Nitrogen	10-12	chorionic somatomammotropin hormone 2	Homo sapiens	90-93
29868651-2	2018	The reaction of carbon disulfide (CS2) with the side-on end-on dinitrogen complex ([NPNSi]Ta)2(mu-eta1:eta2-N2)(mu-H)2 (1) (where [NPNSi] = [PhP(CH2SiMe2NPh)2]) has been studied and shown to generate two products, the ratio of which depends on the concentration of added carbon disulfide.	Nitrogen	63-73	chorionic somatomammotropin hormone 2	Homo sapiens	34-37
29868651-3	2018	At high concentrations of CS2, N-N bond cleavage and functionalization occur to generate a ditantalum complex with an isothiocyanato ligand N-bound to Ta along with bridging sulfido and nitrido moieties.	Nitrogen	31-32	chorionic somatomammotropin hormone 2	Homo sapiens	26-29
29868651-3	2018	At high concentrations of CS2, N-N bond cleavage and functionalization occur to generate a ditantalum complex with an isothiocyanato ligand N-bound to Ta along with bridging sulfido and nitrido moieties.	Nitrogen	33-34	chorionic somatomammotropin hormone 2	Homo sapiens	26-29
29868651-4	2018	At lower concentrations of CS2, less dinitrogen functionalization is observed; instead, N2 is displaced and the CS2 molecule is completely disassembled to generate a ditantalum derivative with bridging methylene and two sulfide moieties.	Nitrogen	88-90	chorionic somatomammotropin hormone 2	Homo sapiens	27-30
29769331-10	2018	This dynamic N-signaling GRN now provides the temporal "transcriptional logic" for 155 candidate TFs to improve nitrogen use efficiency with potential agricultural applications.	Nitrogen	112-120	granulin precursor	Homo sapiens	25-28
29971053-2	2018	Previously, N2 gas flushing of raw milk has demonstrated significant potential as a method to hinder bacterial growth at both laboratory and pilot plant scales.	Nitrogen	12-14	Weaning weight-maternal milk	Bos taurus	35-39
29971053-9	2018	Altogether, this lipidomics study highlights the beneficial effects of N2 flushing treatment on the quality and safety of raw milk through its ability to effectively hinder phospholipolysis during cold storage.	Nitrogen	71-73	Weaning weight-maternal milk	Bos taurus	126-130
29684505-7	2018	This protective effect of SFN might be due to the activation of Nrf2-regulated antioxidant defense deficiencies in the DM mice, as SFN increased the Nrf2 nuclear accumulation and the downstream expression of the antioxidases HO-1 and NQO1 and reduced the levels of the reactive oxygen/nitrogen species (ROS/RNS) in DM mouse brains.	Nitrogen	285-293	nuclear factor, erythroid derived 2, like 2	Mus musculus	64-68
29626814-3	2018	We found that the changes in this coefficient value due to incorporation of nitrogen atoms into the carbon network are related to the spatial configurations of the sp2 bonded carbon atoms, order degree and sp2 clusters size.	Nitrogen	76-84	Sp2 transcription factor	Homo sapiens	164-167
29728506-7	2018	Compared with SLE mice, AIDG23S MRL/lpr mice exhibited decreased proteinuria, blood urea nitrogen, and creatinine, indicating that the loss of SHM contributed to the recovery of renal functions.	Nitrogen	89-97	Fas (TNF receptor superfamily member 6)	Mus musculus	36-39
30857093-4	2018	The lower N/P ratio facilitated the production of leucine aminopeptidase, which was unexpectedly induced by high P but not by low N.	Nitrogen	10-11	carboxypeptidase Q	Homo sapiens	58-72
29626814-3	2018	We found that the changes in this coefficient value due to incorporation of nitrogen atoms into the carbon network are related to the spatial configurations of the sp2 bonded carbon atoms, order degree and sp2 clusters size.	Nitrogen	76-84	Sp2 transcription factor	Homo sapiens	206-209
30857093-4	2018	The lower N/P ratio facilitated the production of leucine aminopeptidase, which was unexpectedly induced by high P but not by low N.	Nitrogen	130-131	carboxypeptidase Q	Homo sapiens	58-72
29627613-4	2018	Infrared spectroscopic confirm that the Pir behaves as a bidentate ligand co-ordinated to the metal ions via the oxygen and nitrogen atoms of nu(CO)carbonyl and nu(CN)pyridyl, respectively.	Nitrogen	124-132	pirin	Homo sapiens	40-43
29800511-7	2018	Importantly, the Fe-PCN/S has a smaller phase nucleation overpotential of polysulfides than nitrogen-doped carbon alone for the formation of nanoscale of Li2S as revealed by ex situ SEM, which enhance lithium-ion diffusion in Li2S, and therefore a high rate performance and remarkable cycle life of Li-sulfur batteries were achieved.	Nitrogen	92-100	pericentrin	Homo sapiens	20-23
29529562-8	2018	The reactivity of ZVI toward Pb(II) followed the increasing order of m-ZVI &lt;&lt; n-ZVI &lt;= Ni/Fe.	Nitrogen	50-51	submaxillary gland androgen regulated protein 3B	Homo sapiens	29-35
29889025-3	2018	Here, we report a common mechanism of N-glycosylation in the protease domains of corin, enteropeptidase and prothrombin in calnexin-mediated glycoprotein folding and extracellular expression.	Nitrogen	38-39	corin, serine peptidase	Homo sapiens	81-86
29889025-3	2018	Here, we report a common mechanism of N-glycosylation in the protease domains of corin, enteropeptidase and prothrombin in calnexin-mediated glycoprotein folding and extracellular expression.	Nitrogen	38-39	coagulation factor II, thrombin	Homo sapiens	108-119
29889025-5	2018	Elimination of N-glycosylation sites in the protease domains of corin, enteropeptidase and prothrombin inhibits corin and enteropeptidase cell surface expression and prothrombin secretion in transfected HEK293 cells.	Nitrogen	15-16	corin, serine peptidase	Homo sapiens	64-69
29889025-5	2018	Elimination of N-glycosylation sites in the protease domains of corin, enteropeptidase and prothrombin inhibits corin and enteropeptidase cell surface expression and prothrombin secretion in transfected HEK293 cells.	Nitrogen	15-16	coagulation factor II, thrombin	Homo sapiens	91-102
29889025-5	2018	Elimination of N-glycosylation sites in the protease domains of corin, enteropeptidase and prothrombin inhibits corin and enteropeptidase cell surface expression and prothrombin secretion in transfected HEK293 cells.	Nitrogen	15-16	corin, serine peptidase	Homo sapiens	112-117
29889025-5	2018	Elimination of N-glycosylation sites in the protease domains of corin, enteropeptidase and prothrombin inhibits corin and enteropeptidase cell surface expression and prothrombin secretion in transfected HEK293 cells.	Nitrogen	15-16	coagulation factor II, thrombin	Homo sapiens	166-177
30083263-13	2018	Tid1 interacted with Galectin-7 through its N-linked glycosylation to promote Tid1-mediated ubiquitination and proteasomal degradation of Galectin-7.	Nitrogen	44-45	galectin 7	Homo sapiens	21-31
30083263-13	2018	Tid1 interacted with Galectin-7 through its N-linked glycosylation to promote Tid1-mediated ubiquitination and proteasomal degradation of Galectin-7.	Nitrogen	44-45	galectin 7	Homo sapiens	138-148
29891966-7	2018	The inhibition of N-glycosylation by tunicamycin or glucose starvation markedly reduced proIGF-1Ea and mature IGF-1 production.	Nitrogen	18-19	insulin like growth factor 1	Homo sapiens	91-96
29501031-4	2018	The nitrogen removal was suppressed and could recover to the initial level during the same period under 10-20 mg L-1 Fe (II), while it did not recover to the initial level under 30 mg L-1 Fe (II) and showed no recovery performance under 50 mg L-1 Fe (II).	Nitrogen	4-12	immunoglobulin kappa variable 1-16	Homo sapiens	113-116
29710522-8	2018	Serum analysis revealed that CCl4 intoxication increased the levels of bilirubin and blood urea nitrogen (BUN).	Nitrogen	96-104	C-C motif chemokine ligand 4	Rattus norvegicus	29-33
29605331-9	2018	The CIN tended to decrease protozoal counts, microbial N flow, and neutral detergent fiber digestibility but tended to increase biohydrogenation of total C18, 18:2, and 18:3.	Nitrogen	6-7	Bardet-Biedl syndrome 9	Homo sapiens	154-157
29465768-1	2018	Denitrification, the microbial conversion of NO3- to N gases, is an important process contributing to whether lotic and riparian ecosystems act as sinks for excess NO3- from agricultural activities.	Nitrogen	45-46	NBL1, DAN family BMP antagonist	Homo sapiens	164-167
29675916-7	2018	In addition, significant positive correlations were observed between ApoA4 and blood urea nitrogen levels and between ApoA4 and creatine levels, while significant negative correlations were seen between serum protein levels and between serum albumin levels in comparisons of DM and DN samples.	Nitrogen	90-98	apolipoprotein A4	Homo sapiens	69-74
29675916-9	2018	Levels of ApoA4 were positively correlated with blood urea nitrogen and creatine, but negatively correlated with serum protein and albumin.	Nitrogen	59-67	apolipoprotein A4	Homo sapiens	10-15
29401627-6	2018	We characterized the N-glycosylation profile of mouse colonic mucin (Muc)-2 by MS and showed that the interaction with mDectin-2 was mediated by high-mannose N-glycans.	Nitrogen	21-22	C-type lectin domain family 4, member n	Mus musculus	119-128
29858715-0	2018	Unusual N-type glycosylation of salivary prolactin-inducible protein (PIP): multiple LewisY epitopes generate highly-fucosylated glycan structures.	Nitrogen	8-9	prolactin induced protein	Homo sapiens	41-68
29858715-0	2018	Unusual N-type glycosylation of salivary prolactin-inducible protein (PIP): multiple LewisY epitopes generate highly-fucosylated glycan structures.	Nitrogen	8-9	prolactin induced protein	Homo sapiens	70-73
29858715-4	2018	Here, we present the analysis of the N-glycosylation of PIP isolated from different sources by LC-MS(/MS) and 1H-NMR.	Nitrogen	37-38	prolactin induced protein	Homo sapiens	56-59
29858715-5	2018	We found a very uncommon N-type glycosylation of PIP in healthy individuals from both, seminal fluid and saliva.	Nitrogen	25-26	prolactin induced protein	Homo sapiens	49-52
29860377-0	2018	Nitrate Reductase Modulation in Response to Changes in C/N Balance and Nitrogen Source in Arabidopsis.	Nitrogen	71-79	nitrate reductase 1	Arabidopsis thaliana	0-17
29686055-4	2018	Mutation of RAPTOR1B resulted in a strong reduction of TOR kinase activity, leading to massive changes in central carbon and nitrogen metabolism, accumulation of excess starch, and induction of autophagy.	Nitrogen	125-133	target of rapamycin	Arabidopsis thaliana	15-18
29860377-7	2018	Photochemical efficiency of PSII did not show significant differences between the two sources of nitrogen after 24 h. The actual nitrate reductase activity was the result of a combination of activity, activation state and protein level.	Nitrogen	97-105	nitrate reductase 1	Arabidopsis thaliana	129-146
31458755-6	2018	A comparison between Pt/N-pGF and commercial Pt/C shows that Pt/N-pGF has superior performance, based on its more positive onset potential and higher limiting diffusion current at -0.5 V.	Nitrogen	24-25	placental growth factor	Homo sapiens	26-29
29898524-9	2018	However, long-term N addition changed the responses of specific N transformation rates to N addition markedly, especially for the rates of nitrification, organic N mineralization to NH4+, NO3- immobilization and dissimilatory NO3- reduction to NH4+ (DNRA).	Nitrogen	19-20	NBL1, DAN family BMP antagonist	Homo sapiens	188-191
29898524-9	2018	However, long-term N addition changed the responses of specific N transformation rates to N addition markedly, especially for the rates of nitrification, organic N mineralization to NH4+, NO3- immobilization and dissimilatory NO3- reduction to NH4+ (DNRA).	Nitrogen	19-20	NBL1, DAN family BMP antagonist	Homo sapiens	226-229
29284210-4	2018	Based on the achieved results, multiple genomic variations in Nsp2, a unique N-glycosylation site (N33 K33), and a K151 amino acid (AA) substitution for virulence in the GP5 of FZ16A were detected; except the 30 AA deletion in the Nsp2-coding region.	Nitrogen	62-63	glycoprotein V platelet	Homo sapiens	170-173
31458755-6	2018	A comparison between Pt/N-pGF and commercial Pt/C shows that Pt/N-pGF has superior performance, based on its more positive onset potential and higher limiting diffusion current at -0.5 V.	Nitrogen	24-25	placental growth factor	Homo sapiens	66-69
29846664-6	2018	Spatial variation of a signal ratio of sp3/sp2 was visualized and was confirmed as a relation between sp3 boding amount and nitrogen content x.	Nitrogen	124-132	Sp3 transcription factor	Homo sapiens	39-42
29846664-4	2018	Furthermore, the dependence of spectral intensity distribution on x suggests the presence of sp2: C-N and sp3: C-N bonding.	Nitrogen	100-101	Sp2 transcription factor	Homo sapiens	93-96
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	CD4 molecule	Homo sapiens	111-114
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	CD3 delta subunit of T-cell receptor complex	Homo sapiens	116-120
29846664-5	2018	Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms.	Nitrogen	102-110	Sp2 transcription factor	Homo sapiens	149-152
29846664-5	2018	Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms.	Nitrogen	102-110	Sp2 transcription factor	Homo sapiens	187-190
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	CD40 ligand	Homo sapiens	125-131
29846664-6	2018	Spatial variation of a signal ratio of sp3/sp2 was visualized and was confirmed as a relation between sp3 boding amount and nitrogen content x.	Nitrogen	124-132	Sp2 transcription factor	Homo sapiens	43-46
29846664-5	2018	Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms.	Nitrogen	102-110	Sp3 transcription factor	Homo sapiens	200-203
29846664-6	2018	Spatial variation of a signal ratio of sp3/sp2 was visualized and was confirmed as a relation between sp3 boding amount and nitrogen content x.	Nitrogen	124-132	Sp3 transcription factor	Homo sapiens	102-105
29415250-10	2018	Total soil nitrogen (TN, positively) and total organic carbon (TOC, negatively) are the most important explanatory factors for SLA variation at both intra- and interspecific levels.	Nitrogen	11-19	Src like adaptor	Homo sapiens	127-130
29722982-2	2018	In this reaction, one C-N bond was cleaved, and two new C-N bonds and one C(sp2)-C(sp2) bond were constructed in one pot.	Nitrogen	24-25	Sp2 transcription factor	Homo sapiens	74-79
29722982-2	2018	In this reaction, one C-N bond was cleaved, and two new C-N bonds and one C(sp2)-C(sp2) bond were constructed in one pot.	Nitrogen	24-25	Sp2 transcription factor	Homo sapiens	81-86
29415250-11	2018	SLA, both within and between species, decreases with decreasing soil nitrogen availability.	Nitrogen	69-77	Src like adaptor	Homo sapiens	0-3
29415250-13	2018	Conclusions: For woody plants low SLA is a phenotypic and probably adaptive response to nitrogen stress, which drives the predominance of species with ever-decreasing SLA towards less fertile habitats.	Nitrogen	88-96	Src like adaptor	Homo sapiens	34-37
29415250-13	2018	Conclusions: For woody plants low SLA is a phenotypic and probably adaptive response to nitrogen stress, which drives the predominance of species with ever-decreasing SLA towards less fertile habitats.	Nitrogen	88-96	Src like adaptor	Homo sapiens	167-170
29696258-1	2018	Herein, a new label-free and blocker-free photoelectrochemical (PEC) sensor based on bifunctional CC-DEVD-peptide modified nitrogen-doped porous carbon-ZnO nanopolyhedra/CdS hybrids is developed for highly sensitive caspase-3 assay.	Nitrogen	123-131	caspase 3	Homo sapiens	216-225
29747438-4	2018	We have designed and evaluated in vitro and in silico some new analogues of GABA, where the nitrogen atom at the gamma-position is embedded in heterocyclic scaffolds and determined their inhibitory potential over the GABA-AT enzyme from Pseudomonas fluorescens.	Nitrogen	92-100	4-aminobutyrate aminotransferase	Homo sapiens	217-224
29676410-0	2018	Newly proposed proton-abstraction roundabout with backside attack mechanism for the SN2 reaction at the nitrogen center in F- + NH2Cl.	Nitrogen	104-112	solute carrier family 38 member 5	Homo sapiens	84-87
29965503-3	2018	It was shown that nitrogen pollution, which was dominated by nitrate (NO3-), existed in the four reservoirs.	Nitrogen	18-26	NBL1, DAN family BMP antagonist	Homo sapiens	70-73
29577899-7	2018	N-glycosylation of alphavbeta3 and alphavbeta6 integrins is required for the attachment of cells to ECM proteins like fibronectin.	Nitrogen	0-1	fibronectin 1	Homo sapiens	118-129
29648809-1	2018	Herein described are the first efficient nitrogen-atom transfer reactions mediated by iron N, N"-dimethyl- N, N"-bis(2-pyridinylmethyl)cyclohexane-1,2-diamine- (MCP-) and 2-({1-[(pyridin-2-ylmethyl)pyrrolidin-2-yl]pyrrolidin-1-yl}methyl)pyridine-type (PDP-type) complexes.	Nitrogen	41-49	CD46 molecule	Homo sapiens	161-164
29725770-11	2018	In Ashtamudi, the concentration of NO3--N in overlying water was very less, which suggests reduced nitrogen yield in the estuary from the fluvial input of Kallada River and agricultural runoff.	Nitrogen	99-107	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
29638108-1	2018	In this work, a versatile photoelectrochemical paper-based sensor based on N-carbon dots/TiO2-Pt-modified paper in situ is developed for sensitive detection of carcinoembryonic antigen (CEA) in clinical serum samples.	Nitrogen	75-76	CEA cell adhesion molecule 3	Homo sapiens	160-184
29638108-1	2018	In this work, a versatile photoelectrochemical paper-based sensor based on N-carbon dots/TiO2-Pt-modified paper in situ is developed for sensitive detection of carcinoembryonic antigen (CEA) in clinical serum samples.	Nitrogen	75-76	CEA cell adhesion molecule 3	Homo sapiens	186-189
29717998-3	2018	Recombinant AKR1C3 with a thrombin-cleavable N-terminal His6 tag was expressed from a pET-28(+) vector for structural studies of enzyme-inhibitor complexes.	Nitrogen	45-46	coagulation factor II, thrombin	Homo sapiens	26-34
29965503-4	2018	Greater human activities caused more nitrogen pollution (average NO3- concentration 0.21 mmol  L-1) in the Qingshan reservoir.	Nitrogen	37-45	NBL1, DAN family BMP antagonist	Homo sapiens	65-68
29676410-2	2018	Nonetheless, the SN2 reaction at the nitrogen center has received scarce attention and is less understood.	Nitrogen	37-45	solute carrier family 38 member 5	Homo sapiens	17-20
29676410-3	2018	Herein, we propose a new reaction mechanism for the SN2 reaction at the nitrogen center in the F- + NH2Cl reaction using ab initio molecular dynamics calculations.	Nitrogen	72-80	solute carrier family 38 member 5	Homo sapiens	52-55
29676410-5	2018	The double-inversion mechanism revealed recently for the SN2 reaction at the carbon center is also observed for the title reaction at the nitrogen center.	Nitrogen	138-146	solute carrier family 38 member 5	Homo sapiens	57-60
28446076-7	2018	In contrast, HI 6 and 2-PAM showed high binding energy values with great contribution of the amino acid Asp74, demonstrating the importance of the quaternary nitrogen to the affinity and interaction of the oximes/AChE tabun-inhibited complexes.	Nitrogen	158-166	acetylcholinesterase (Cartwright blood group)	Homo sapiens	213-217
29384693-8	2018	This response was attenuated by N-linked glycosylation inhibition, suggesting that palmitate impacts expression of the fully activated glycoform of COX-2.	Nitrogen	32-33	prostaglandin-endoperoxide synthase 2	Homo sapiens	148-153
29715089-7	2018	RESULTS: Two pentabromobenzyl isothiourea bromide derivatives, ZKK-13 and N,N,N"-trimethyl-ZKK1 (TRIM), exhibited the most potent cytotoxic and proapoptotic efficacies against human glioma-derived cells, even at a very low concentration (1 muM).	Nitrogen	74-76	latexin	Homo sapiens	240-243
29602984-0	2018	Interactions between carbon and nitrogen sources depend on RIM15 and determine fermentative or respiratory growth in Saccharomyces cerevisiae.	Nitrogen	32-40	protein kinase RIM15	Saccharomyces cerevisiae S288C	59-64
29602984-7	2018	This study reveals the existence of synergic and diverse roles of carbon and nitrogen sources that are affected by RIM15, influencing the fermentative and respiratory growth of S. cerevisiae.	Nitrogen	77-85	protein kinase RIM15	Saccharomyces cerevisiae S288C	115-120
29431199-0	2018	N-glycosylation by N-acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin beta1 and promotes HCC metastasis.	Nitrogen	0-1	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	19-52
29431199-5	2018	Moreover, we showed that the PI3K/Akt pathway regulates GnT-V expression and that inhibition of GnT-V-mediated N-glycosylation suppressed PI3K signaling.	Nitrogen	111-112	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	96-101
29431199-2	2018	In the current study, we report that GnT-V-mediated N-glycosylation of CD147/basigin, a tumor-associated glycoprotein that carries beta1,6-N-acetylglucosamine (beta1,6-GlcNAc) glycans, is upregulated during TGF-beta1-induced epithelial-to-mesenchymal transition (EMT), which correlates with tumor metastasis in patients with hepatocellular carcinoma (HCC).	Nitrogen	52-53	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	37-42
29431199-2	2018	In the current study, we report that GnT-V-mediated N-glycosylation of CD147/basigin, a tumor-associated glycoprotein that carries beta1,6-N-acetylglucosamine (beta1,6-GlcNAc) glycans, is upregulated during TGF-beta1-induced epithelial-to-mesenchymal transition (EMT), which correlates with tumor metastasis in patients with hepatocellular carcinoma (HCC).	Nitrogen	52-53	transforming growth factor beta 1	Homo sapiens	207-216
29725404-12	2018	By contrast, co-treatment of PLC/PRF/5 cells with 500 micromol/l NaHS and 20 micromol/l NS-398 inhibited the NaHS-induced increase in the expression level of p-STAT3.	Nitrogen	88-90	signal transducer and activator of transcription 3	Homo sapiens	160-165
29579393-4	2018	The comparison clearly illustrates that increasing the s-character of the nitrogen lone pair decreases the hydrogen-bond acceptor strength (sp3 &gt; sp2 &gt; sp).	Nitrogen	74-82	Sp3 transcription factor	Homo sapiens	140-143
29620895-6	2018	The initial reaction path of thermal decomposition of CL-20 is N-NO2 cleavage to form NO2, followed by C-N cleavage, leading to the destruction of the cage structure.	Nitrogen	63-64	epithelial membrane protein 1	Homo sapiens	54-59
29604581-2	2018	Based on structure-activity relationship, N-substituents with a branched chain and a shorter carbon chain on the amidine N-atom exhibited more promising activity against Gram-negative and MDR-Gram-positive bacteria; compounds 5c and 5i were the most powerful candidate compounds.	Nitrogen	121-122	malic enzyme complex, mitochondrial	Mus musculus	188-191
29611701-2	2018	Herein, we present a novel and facile route for synthesis of iron-, cobalt-, and nitrogen-codoped carbon nanopolyhedra electrocatalysts (Fe,Co,N-CNP) by one-step pyrolysis of a new type of Fe/Co bimetal zeolitic imidazolate framework (Fe,Co-ZIF) crystals that were self-assembled by oxygen-free solvothermal reaction of Fe2+ and Co2+ with 2-methylimidazole.	Nitrogen	81-89	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	145-148
30014643-0	2018	[The Relationship of Clinicopathology of p16 in Non-small Cell Lung Cancer and 5-nitrogen impurity-2"-deoxycytidine-nitrogen Impurity on the Influence of p16 Expression in Lung Cancer A549 Cells].	Nitrogen	81-89	cyclin dependent kinase inhibitor 2A	Homo sapiens	41-44
30014643-0	2018	[The Relationship of Clinicopathology of p16 in Non-small Cell Lung Cancer and 5-nitrogen impurity-2"-deoxycytidine-nitrogen Impurity on the Influence of p16 Expression in Lung Cancer A549 Cells].	Nitrogen	81-89	cyclin dependent kinase inhibitor 2A	Homo sapiens	154-157
29604581-2	2018	Based on structure-activity relationship, N-substituents with a branched chain and a shorter carbon chain on the amidine N-atom exhibited more promising activity against Gram-negative and MDR-Gram-positive bacteria; compounds 5c and 5i were the most powerful candidate compounds.	Nitrogen	42-43	malic enzyme complex, mitochondrial	Mus musculus	188-191
29377298-1	2018	The hybrid ligand 3-(2,2"-bipyridine-6-ylmethyl)-1-mesityl-1H-imidazolylidene (NHCBipy ) featuring both carbene and N-donor sites, was selectively complexed with various d10 metal cations in order to examine its coordination behavior with regard to homo and heterometallic structures.	Nitrogen	79-80	CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion	Homo sapiens	170-173
30108983-5	2018	Herein, we postulate that thioflavin T (ThT), due to its physico-chemical attributes, such as moderate lipophilicity and protonated nitrogen, could very well be recognized as a transport substrate of Pgp (P-glycoprotein, ABCB1) thus restricting its permeation into the brain.	Nitrogen	132-140	ATP binding cassette subfamily B member 1	Homo sapiens	200-203
29579393-4	2018	The comparison clearly illustrates that increasing the s-character of the nitrogen lone pair decreases the hydrogen-bond acceptor strength (sp3 &gt; sp2 &gt; sp).	Nitrogen	74-82	Sp2 transcription factor	Homo sapiens	149-152
29537846-3	2018	Nitrogen extrusion in Delta1-pyrazolines and further reduction of the sulfinyl group yielded the target compounds in good overall yield.	Nitrogen	0-8	delta like non-canonical Notch ligand 1	Homo sapiens	22-28
29650959-4	2018	We develop a nanozyme using nitrogen-doped porous carbon nanospheres which possess four enzyme-like activities (oxidase, peroxidase, catalase and superoxide dismutase) responsible for reactive oxygen species regulation.	Nitrogen	28-36	catalase	Homo sapiens	133-141
29451981-0	2018	High Performance Anion Exchange and Hydrophilic Interaction Liquid Chromatography Approaches for Comprehensive Mass Spectrometry-Based Characterization of the N-Glycome of a Recombinant Human Erythropoietin.	Nitrogen	159-160	erythropoietin	Homo sapiens	192-206
29074237-4	2018	The reported delta15N-NO3- values for sources of NO3- are: soil organic N - +3%-+8%, mineral fertilizers - -8%-+7%; manure/household waste - +5% to +35%.	Nitrogen	20-21	NBL1, DAN family BMP antagonist	Homo sapiens	22-25
29074237-4	2018	The reported delta15N-NO3- values for sources of NO3- are: soil organic N - +3%-+8%, mineral fertilizers - -8%-+7%; manure/household waste - +5% to +35%.	Nitrogen	20-21	NBL1, DAN family BMP antagonist	Homo sapiens	49-52
29367051-14	2018	The influence of NO3-, NO2-, IC and heavy metal Pb and Zn on bacterial community might via their influence on the functional groups involving nitrogen, carbon and metal metabolisms.	Nitrogen	142-150	NBL1, DAN family BMP antagonist	Homo sapiens	17-20
29519914-1	2018	Protein synthesis, transport, and N-glycosylation are coupled at the mammalian endoplasmic reticulum by complex formation of a ribosome, the Sec61 protein-conducting channel, and oligosaccharyltransferase (OST).	Nitrogen	34-35	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	179-204
29519914-1	2018	Protein synthesis, transport, and N-glycosylation are coupled at the mammalian endoplasmic reticulum by complex formation of a ribosome, the Sec61 protein-conducting channel, and oligosaccharyltransferase (OST).	Nitrogen	34-35	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	206-209
29965002-3	2018	For the granules, the highest specific nitrogen removal rate of q(TN)=(17.7+-1.0) mg (g h)-1 was obtained at a DO concentration of 2 mg L-1, while the initial NH4+-N concentration was set at 100 mg L-1.	Nitrogen	39-47	immunoglobulin kappa variable 1-16	Homo sapiens	136-139
29965002-3	2018	For the granules, the highest specific nitrogen removal rate of q(TN)=(17.7+-1.0) mg (g h)-1 was obtained at a DO concentration of 2 mg L-1, while the initial NH4+-N concentration was set at 100 mg L-1.	Nitrogen	39-47	immunoglobulin kappa variable 1-16	Homo sapiens	198-201
29881821-6	2018	These results were confirmed by quantification analysis of NTCP 55-kDa N-glycosylated bands, which showed significantly less total NTCP protein in donors below 1 year of age compared to donors older than 1 year.	Nitrogen	59-60	solute carrier family 10 member 1	Homo sapiens	131-135
29400411-10	2018	They linked to COX-2 through the N atom of the azole scaffold, while C O of the oxazolone moiety was responsible for the binding to amino acids inside the LOX active site.	Nitrogen	33-34	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	15-20
29417482-5	2018	The results showed that addition of 25 mg L-1 fullerene C60 to urea plant wastewater could increase water uptake and nitrogen recovery of the teak plants.	Nitrogen	117-125	immunoglobulin kappa variable 1-16	Homo sapiens	42-45
29413996-4	2018	Maximum bio-oil yield of 38.1 wt% was obtained at pyrolysis temperature of 550  C, heating rate of 20  C min-1 and nitrogen flow rate of 226 mL min-1.	Nitrogen	115-123	CD59 molecule (CD59 blood group)	Homo sapiens	144-149
28387149-5	2018	The ammoniacal nitrogen removal ratio decreased under high organic matter concentration (above 100 mg L-1) and low DO (less than 1 mg L-1) condition.	Nitrogen	15-23	immunoglobulin kappa variable 1-16	Homo sapiens	102-105
28387149-5	2018	The ammoniacal nitrogen removal ratio decreased under high organic matter concentration (above 100 mg L-1) and low DO (less than 1 mg L-1) condition.	Nitrogen	15-23	immunoglobulin kappa variable 1-16	Homo sapiens	134-137
29417482-7	2018	However, addition of 50 mg L-1 fullerene C60 to the wastewater decreased the values for water uptake and nitrogen recovery.	Nitrogen	105-113	immunoglobulin kappa variable 1-16	Homo sapiens	27-30
29622567-0	2018	Repression of Nitrogen Starvation Responses by Members of the Arabidopsis GARP-Type Transcription Factor NIGT1/HRS1 Subfamily.	Nitrogen	14-22	myb-like transcription factor family protein	Arabidopsis thaliana	111-115
29628090-3	2018	In Test 1 of 95% AEB, removal rates of ammonia, total nitrogen (TN) and chemical oxygen demand (COD) reached 99.34%+-0.11%, 99.34%+-0.10% and 90.79%+-0.12%, respectively.	Nitrogen	54-62	serine protease 21	Homo sapiens	3-9
32172531-1	2018	The human ether-a-go-go related gene (hERG)-encoded channel hERG undergoes N-linked glycosylation at position 598, which is located in the unusually long S5-pore linker of the channel.	Nitrogen	75-76	ETS transcription factor ERG	Homo sapiens	38-42
32172531-1	2018	The human ether-a-go-go related gene (hERG)-encoded channel hERG undergoes N-linked glycosylation at position 598, which is located in the unusually long S5-pore linker of the channel.	Nitrogen	75-76	ETS transcription factor ERG	Homo sapiens	60-64
32172531-9	2018	In summary, our results revealed that N-linked glycosylation protects hERG against protease-mediated degradation and thus contributes to hERG channel stability on the plasma membrane.- Lamothe, S. M., Hulbert, M., Guo, J., Li, W., Yang, T., Zhang, S. Glycosylation stabilizes hERG channels on the plasma membrane by decreasing proteolytic susceptibility.	Nitrogen	38-39	ETS transcription factor ERG	Homo sapiens	70-74
32172531-9	2018	In summary, our results revealed that N-linked glycosylation protects hERG against protease-mediated degradation and thus contributes to hERG channel stability on the plasma membrane.- Lamothe, S. M., Hulbert, M., Guo, J., Li, W., Yang, T., Zhang, S. Glycosylation stabilizes hERG channels on the plasma membrane by decreasing proteolytic susceptibility.	Nitrogen	38-39	ETS transcription factor ERG	Homo sapiens	137-141
32172531-9	2018	In summary, our results revealed that N-linked glycosylation protects hERG against protease-mediated degradation and thus contributes to hERG channel stability on the plasma membrane.- Lamothe, S. M., Hulbert, M., Guo, J., Li, W., Yang, T., Zhang, S. Glycosylation stabilizes hERG channels on the plasma membrane by decreasing proteolytic susceptibility.	Nitrogen	38-39	ETS transcription factor ERG	Homo sapiens	137-141
29881418-8	2018	BUN (blood urea nitrogen) and creatinine (Cr) concentrations were significantly increased in BRI+V group 24 h after reperfusion.	Nitrogen	16-24	integral membrane protein 2B	Rattus norvegicus	93-96
29881433-6	2018	The N-demethylation pathway was indirectly affected by CYP2D6 phenotypic differences.	Nitrogen	4-5	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	55-61
29429687-5	2018	The optimal overall yields of both NO2- and NO3- were obtained at the N2/O2 volume (in the sparged gas) ratio of 3:1 which is near to the ratio of N2/O2 in air.	Nitrogen	70-72	NBL1, DAN family BMP antagonist	Homo sapiens	44-47
29407902-8	2018	Collectively, these results indicate that dietary n-3 PUFA supplementation can modulate gene expression of key enzymes in prostaglandin biosynthetic pathway during early gestation, which in turn might have beneficial impact on overall reproductive response in breeding sows.	Nitrogen	29-30	Polyunsaturated fatty acid percentage	Sus scrofa	54-58
29055589-8	2018	The higher NH3-N and the lower NO3-N of the pore water samples in summer versus autumn suggested that organic nitrogen decomposition via an ammonification and nitrification process could operate as an important factor for the SOD variations in summer and autumn, respectively.	Nitrogen	110-118	superoxide dismutase 1	Homo sapiens	226-229
29055589-9	2018	Principal component analysis revealed the mutual contributions of nitrogen-associated processes and the organic composition in pore water to increasing SOD levels.	Nitrogen	66-74	superoxide dismutase 1	Homo sapiens	152-155
29429687-5	2018	The optimal overall yields of both NO2- and NO3- were obtained at the N2/O2 volume (in the sparged gas) ratio of 3:1 which is near to the ratio of N2/O2 in air.	Nitrogen	147-149	NBL1, DAN family BMP antagonist	Homo sapiens	44-47
29632491-6	2018	Pharmacological inhibition of HDAC6 by 23BB pretreatment significantly reduced serum creatinine and serum blood urea nitrogen (BUN) levels as well as attenuated renal tubular damage in GL-injured kidneys.	Nitrogen	117-125	histone deacetylase 6	Mus musculus	30-35
29534488-4	2018	Both quaternization upon methylation of the quinoline nitrogen atom, and tethering of a triazole ring, with, in some cases, the additional incorporation of a polyphenol-like moiety, result in more polar compounds with higher inhibitory activity against human AChE (up to 190-fold) and butyrylcholinesterase (up to 40-fold) than pyridostigmine, the standard drug for symptomatic treatment of myasthenia gravis.	Nitrogen	54-62	acetylcholinesterase (Cartwright blood group)	Homo sapiens	259-263
29031885-0	2018	Multiple signal-amplification via Ag and TiO2 decorated 3D nitrogen doped graphene hydrogel for fabricating sensitive label-free photoelectrochemical thrombin aptasensor.	Nitrogen	59-67	coagulation factor II, thrombin	Homo sapiens	150-158
32226136-3	2018	Obtained molecular parameters confirm the hyperconjugation in the pyridine ring and the sp2 hybridization concept of the nitrogen and carbon atoms in the ring.	Nitrogen	121-129	Sp2 transcription factor	Homo sapiens	88-91
33418784-7	2018	In contrast to class C CpG ODNs, which also simultaneously induce IFN-alpha and IL-6, the ratio of IFN-alpha and IL-6 induced by PEI-CpG ODN NPs could be regulated by changing the N/P ratio.	Nitrogen	29-30	interleukin 6	Homo sapiens	80-84
29498521-1	2018	The SN2 reactions at nitrogen center (SN2@N) play a significant role in organic synthesis, carcinogenesis, and the formation of some environmentally toxic compounds.	Nitrogen	21-29	solute carrier family 38 member 5	Homo sapiens	4-7
29498521-1	2018	The SN2 reactions at nitrogen center (SN2@N) play a significant role in organic synthesis, carcinogenesis, and the formation of some environmentally toxic compounds.	Nitrogen	21-29	solute carrier family 38 member 5	Homo sapiens	38-41
29132001-2	2018	In addition, the concentration of NO3- in acid rain increases with the rapidly growing of nitrogen deposition.	Nitrogen	90-98	NBL1, DAN family BMP antagonist	Homo sapiens	34-37
29424521-8	2018	In addition, the N/Cl-CDs show obvious fluorescence response to cytochrome c (cyt- c) with a detection limit of 3.6 mg L-1 (ca.	Nitrogen	17-18	cytochrome c, somatic	Homo sapiens	64-76
29965477-5	2018	The analysis of the nitrogen conversion characteristics in two regions showed that the AOB had been in a dominant position in the aerobic zone, and the NOB was inhibited by DO and the matrix, NPRa increased from 0.22 kg (m3 d)-1 to 0.58 kg (m3 d)-1, and NAPa could reach 95% with the increase in anaerobic denitrification capacity.	Nitrogen	20-28	natriuretic peptide receptor 1	Homo sapiens	192-196
29424521-8	2018	In addition, the N/Cl-CDs show obvious fluorescence response to cytochrome c (cyt- c) with a detection limit of 3.6 mg L-1 (ca.	Nitrogen	17-18	cytochrome c, somatic	Homo sapiens	78-84
29187368-1	2018	Epithelial Na+ channel (ENaC) subunits undergo N-linked glycosylation in the endoplasmic reticulum where they assemble into an alphabetagamma complex.	Nitrogen	11-12	sodium channel epithelial 1 subunit gamma	Rattus norvegicus	24-28
29053817-8	2018	Moreover, we found that concanamycin A treatment prevented the degradation of ribosomal proteins RPS6 and RPL37 under nitrogen or phosphate deprivation.	Nitrogen	118-126	ribosomal protein L37	Chlamydomonas reinhardtii	106-111
29876214-6	2018	A 2.3 V aqueous GQD/MnO2-3//nitrogen-doped graphene ASC is assembled, which exhibits the high energy density of 118 Wh kg-1 at the power density of 923 W kg-1.	Nitrogen	28-36	PYD and CARD domain containing	Homo sapiens	52-55
29498673-4	2018	Remarkably, though, despite the fact that all membrane-bound TRAIL receptors harbor putative glycosylation sites, only pro-apoptotic signaling through DR4 and DR5 has, so far, been found to be regulated by N- and O-glycosylation, respectively.	Nitrogen	206-207	TNF superfamily member 10	Homo sapiens	61-66
27275644-1	2018	Part 5: Non-aromatic sp2 nitrogen containing compounds.	Nitrogen	25-33	tankyrase	Homo sapiens	0-6
29323465-3	2018	Time course induction of ER stress, using tunicamycin (TM), shows a group of genes such as Chop, Trb3, Sqstm1, Grp78, and Herpud1 respond rapidly to TM inhibition of N-glycosylation, while others such as Atf5, Odz4, and Birc5 exhibits a delayed response.	Nitrogen	166-167	teneurin-4	Cricetulus griseus	210-214
29247929-4	2018	However, the photocatalytic fuel cell was still able to perform 37% of decolorization in a slow rate (k = 0.033 h-1) under extremely low dissolved oxygen concentration (approximately 0.2 mg L-1) when nitrogen gas was introduced into the fuel cell throughout the 8 h. However, the change of the UV-Vis spectrum indicates that the intermediates of the dye could not be mineralized under insufficient dissolved oxygen level.	Nitrogen	200-208	immunoglobulin kappa variable 1-16	Homo sapiens	190-193
29519444-4	2018	In this work, we reported a novel, green, economic approach for preparation of nitrogen doped CDs by directly microwave-assisted heating small organic molecules at 120 C for 5min using Glu and amino group of MPD as the precursors and ethylene glycol as solvent.	Nitrogen	79-87	mevalonate diphosphate decarboxylase	Homo sapiens	208-211
29245148-14	2018	NO3- of river water in the upper reaches are come from nitrogen in precipitation and soil organic N. River water in the lower reaches is polluted by a mixture of soil organic N and fertilizers.	Nitrogen	55-63	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
29519422-3	2018	Plasma functionalized (N2 and O2) and stabilized Graphene Oxide (GO) thin layers in a hybrid with amorphous carbon (aC) induced the expression of vascular endothelial growth factor (VEGF) and osteoprotegerin (OPG) growth factors in fibroblasts (hGF) and, more remarkably, in osteoblasts (hFOB) cells confirming the suitability for tissue regeneration and osteo-integration applications.	Nitrogen	23-25	vascular endothelial growth factor A	Homo sapiens	146-180
29519422-3	2018	Plasma functionalized (N2 and O2) and stabilized Graphene Oxide (GO) thin layers in a hybrid with amorphous carbon (aC) induced the expression of vascular endothelial growth factor (VEGF) and osteoprotegerin (OPG) growth factors in fibroblasts (hGF) and, more remarkably, in osteoblasts (hFOB) cells confirming the suitability for tissue regeneration and osteo-integration applications.	Nitrogen	23-25	vascular endothelial growth factor A	Homo sapiens	182-186
29458871-5	2018	It was shown that the dimeric bisbenzimidazoles DBP(n) and DBPA(n) counteract the H-NS silencing activity.	Nitrogen	84-86	Dbp	Escherichia coli	48-51
27275644-1	2018	Part 5: Non-aromatic sp2 nitrogen containing compounds.	Nitrogen	25-33	Sp2 transcription factor	Homo sapiens	21-24
27275644-3	2018	This part is devoted to non-aromatic molecules characterized by a lone pair located on a sp2 nitrogen atom, it embraces functional groups such as imines, amidines, guanidines, diazenes, hydrazines, oximes, and phosphazenes.	Nitrogen	93-101	Sp2 transcription factor	Homo sapiens	89-92
29170910-7	2018	In nitrogen-depleted conditions, starch cannot be invested in PSII-dependent and PSII-independent pathways for H2-production, mainly because of a strong decrease of the cytochrome b 6 f complex of the photosynthetic electron flow.	Nitrogen	3-11	cob	Tetradesmus obliquus	169-181
29445956-0	2018	High Performance of PEDOT:PSS/n-Si Solar Cells Based on Textured Surface with AgNWs Electrodes.	Nitrogen	13-14	PSS	Homo sapiens	26-29
29131928-1	2018	RATIONALE: The nitrogen and oxygen (delta15 N, delta18 O, delta17 O) isotopic compositions of NO3- and NO2- are important tracers of nutrient dynamics in soil, rain, groundwater and oceans.	Nitrogen	15-23	NBL1, DAN family BMP antagonist	Homo sapiens	94-97
29131928-8	2018	RESULTS: NO3- /NO2- nitrogen is routed to the 15 Nalpha position of N2 O in the azide reaction; hence the delta15 Nalpha value should be used for N2 O laser spectrometry results.	Nitrogen	20-28	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
29065215-7	2018	Gene expression experiments showed that, apart from the conventional nitrogen catabolic repression mechanism that is operating in aerobiosis, there seems to be an oxygen-independent mechanism acting to overexpress key genes like GAP1, GDH1, GDH2 and GLT1 to ensure adequate anaerobic growth even in the presence of non-preferential nitrogen source.	Nitrogen	332-340	amino acid permease GAP1	Saccharomyces cerevisiae S288C	229-233
30966264-0	2018	Two New Three-Dimensional Pillared-Layer Co(II) and Cu(II) Frameworks Involving a [M2(EO-N3)2] Motif from a Semi-Flexible N-Donor Ligand, 5,5"-Bipyrimidin: Syntheses, Structures and Magnetic Properties.	Nitrogen	4-5	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	41-47
29445956-3	2018	We have studied interface properties between PEDOT:PSS and textured n-Si by varying coating conditions.	Nitrogen	17-18	PSS	Homo sapiens	51-54
29324345-1	2018	In the present study, a series of multi-target N-substituted cyclic imide derivatives which possessed potent dopamine D2, serotonin 5-HT1A and 5-HT2A receptors properties were synthesized and evaluated as potential antipsychotics.	Nitrogen	47-48	5-hydroxytryptamine receptor 2A	Homo sapiens	145-149
29129847-2	2018	N-dechloroethylation of CP mediated by the enzyme CYP3A4 yields nephrotoxic and neurotoxic chloroacetaldehyde (CAA) in equimolar amount to DECP.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	50-56
29425510-5	2018	Structure-function analyses revealed similar N-C interaction in TRPP2 as well as TRPM8/-V1/-C4 via highly conserved tryptophan and lysine/arginine residues.	Nitrogen	45-46	polycystin 2, transient receptor potential cation channel	Homo sapiens	64-69
29531809-10	2018	The selective inhibition of nuNCX1 by XIP-NLS increased the percentage of beta III tubulin-positive immature neurons in mature cultures of MAP-2-positive cortical neurons, thus unraveling a new function for nuNCX1 in regulating neuronal differentiation through [Ca2+]n-dependent PTEN/PI3K/Akt pathway.	Nitrogen	15-16	AKT serine/threonine kinase 1	Homo sapiens	289-292
29242193-6	2018	Moreover, we mapped two Asn residues within CRD4 that are N-linked glycosylated and mediate m4-1BB binding to Gal-9.	Nitrogen	58-59	lectin, galactose binding, soluble 9	Mus musculus	110-115
29216573-1	2018	Poor nitrogen removal efficiency (mainly nitrate, NO3--N) at low temperatures strongly limits application of subsurface wastewater infiltration systems (SWISs).	Nitrogen	5-13	NBL1, DAN family BMP antagonist	Homo sapiens	50-53
29206917-3	2018	Paraffin sections from N-glycosylation inhibitor tunicamycin treated ER-/PR-/HER2+ (double negative) breast tumor in athymic nude mice exhibited reduced N-glycan but increased GRP78 expression.	Nitrogen	23-24	erb-b2 receptor tyrosine kinase 2	Homo sapiens	77-81
29206917-3	2018	Paraffin sections from N-glycosylation inhibitor tunicamycin treated ER-/PR-/HER2+ (double negative) breast tumor in athymic nude mice exhibited reduced N-glycan but increased GRP78 expression.	Nitrogen	23-24	heat shock protein 5	Mus musculus	176-181
28433002-4	2018	In addition, the strength of hydrogen bond interaction between + N-H and NO3- is stronger than that between + N-H and Ac- , suggesting that anions have a significant influence on microstructure due to the acidity of a Bronsted acid.	Nitrogen	65-66	NBL1, DAN family BMP antagonist	Homo sapiens	73-76
29301962-0	2018	Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation.	Nitrogen	87-88	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	23-48
29034987-10	2018	We thus derived an N-induced global C sink of about 177 (112-243) Tg C/year in aboveground and belowground woody biomass, which would account for about 12% of the forest biomass C sink (1,400 Tg C/year).	Nitrogen	19-20	transglutaminase 2	Homo sapiens	66-70
29034987-10	2018	We thus derived an N-induced global C sink of about 177 (112-243) Tg C/year in aboveground and belowground woody biomass, which would account for about 12% of the forest biomass C sink (1,400 Tg C/year).	Nitrogen	19-20	transglutaminase 2	Homo sapiens	192-196
29273683-0	2018	Functional implications of corticosteroid-binding globulin N-glycosylation.	Nitrogen	59-60	serpin family A member 6	Homo sapiens	27-58
29273683-5	2018	We now show that mutations of conserved N-glycosylation sites at N238 in human CBG and N230 in rat CBG disrupt steroid binding.	Nitrogen	40-41	serpin family A member 6	Homo sapiens	79-82
29247140-7	2018	cnx2-2 plants are small and chlorotic, with severely decreased Moco enzyme activities, but they performed better than a cnx2-1 knockout mutant, which could only survive with ammonia as a nitrogen source.	Nitrogen	187-195	cofactor of nitrate reductase and xanthine dehydrogenase 2	Arabidopsis thaliana	0-4
29349513-5	2018	For the quantitative description of the effects of the hydrophobic contact and nitrogen-heme-iron coordination on aromatase inhibition, the hydrophobicity density field model and the smallest dual descriptor Deltaf(r) S were introduced, respectively.	Nitrogen	79-87	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	114-123
29403519-1	2018	The glutamine synthetase (GS1) is a key enzyme that catalyzes the reaction of glutamate and ammonia to produce glutamine in the nitrogen (N) metabolism.	Nitrogen	128-136	glutamine synthetase	Nicotiana tabacum	4-24
29292454-3	2018	Notably, the cyclometallated Au-C^N complex was identified as the most selective candidate to disrupt the PARP-1 zinc finger domain, forming distinct adducts compared to the coordination compound Auphen.	Nitrogen	0-1	poly(ADP-ribose) polymerase 1	Homo sapiens	106-112
29257867-1	2018	The fundamental biogeochemical cycle of nitrogen includes cytochrome c nitrite reductase, which catalyzes the reduction of nitrite ions to ammonium with eight protons and six electrons (NO2- + 8H+ + 6e-   NH4+ + 2H2O).	Nitrogen	40-48	cytochrome c, somatic	Homo sapiens	58-70
28846901-1	2018	A novel nitrogen-doped biochar embedded with cobalt (Co-NB) was fabricated via pyrolysis of glucose pretreated with melamine (N donor) and Co(II).	Nitrogen	8-16	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	139-145
29324707-6	2018	The binary linear regression model was established to predict N release from PCU because of significant correlations between the cumulative N release rate and concentrations of NO3- and NH4+.	Nitrogen	62-63	NBL1, DAN family BMP antagonist	Homo sapiens	177-180
28892050-8	2018	These functions were modulated by N-acetylglucosaminyltransferase 5 (MGAT5) which mediated N-glycosylation at Asn256 (N256) of CEACAM6.	Nitrogen	34-35	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	69-74
29186951-2	2018	This report presents evidence that thermal decomposition of N-acetylated sugars and amino acids in heated gas chromatograph injectors contributes to artifactual acetamide in milk and beef.	Nitrogen	60-61	Weaning weight-maternal milk	Bos taurus	174-178
29965687-4	2018	The SAD process performed well with an average total nitrogen concentration in the effluent of 6.41 mg L-1 when 30 mg L-1 glucose was added to the effluent sewage at ambient temperature.	Nitrogen	53-61	immunoglobulin kappa variable 1-16	Homo sapiens	103-106
29965687-7	2018	In normal and low temperature environments, the SAD process functioned well, and the average total nitrogen concentration of the effluent was 6.54 mg L-1 when 30 mg L-1 sodium propionate was added in the influent sewage.	Nitrogen	99-107	immunoglobulin kappa variable 1-16	Homo sapiens	150-153
29965687-7	2018	In normal and low temperature environments, the SAD process functioned well, and the average total nitrogen concentration of the effluent was 6.54 mg L-1 when 30 mg L-1 sodium propionate was added in the influent sewage.	Nitrogen	99-107	immunoglobulin kappa variable 1-16	Homo sapiens	165-168
29965691-7	2018	In the recovery phase, the nitrogen removal performance of the reactor could almost reach its initial level at nZVI=0 mg L-1 during an operation of 20 days due to the fast growth of heterotrophic microbes on the surface of the DGS.	Nitrogen	27-35	immunoglobulin kappa variable 1-16	Homo sapiens	121-124
29456791-0	2018	Nonacidic Chemotype Possessing N-Acylated Piperidine Moiety as Potent Farnesoid X Receptor (FXR) Antagonists.	Nitrogen	0-1	xenotropic and polytropic retrovirus receptor 1	Homo sapiens	80-90
28892050-10	2018	In conclusion, the complex N-glycosylation of CEACAM6 is critical for EGFR signaling of OSCC invasion and metastasis.	Nitrogen	27-28	epidermal growth factor receptor	Homo sapiens	70-74
29231218-1	2018	We successfully developed an approach to synthesize a metal oxide- and N-codoped carbon nanosheet, NC@CoO/CuO, derived from a metal-organic framework nanofiber, Cu(ii)-Asp@Co(II) (Asp = l-aspartate).	Nitrogen	71-72	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	172-178
29239440-4	2018	A mononuclear cationic coordination motif was found for PPh3 or DPEPhos with all N^N ligands, which exhibits blue to green luminescence of MLCT character d(Cu)   pi*(pyridine-amine ligand) with quantum yields up to 46%.	Nitrogen	81-84	caveolin 1	Homo sapiens	56-60
29295953-4	2018	The turnover of BiP was in part driven by its amino-terminal arginylation (Nt-arginylation) by the arginyltransferase ATE1, which generated an autophagic N-degron of the N-end rule pathway.	Nitrogen	75-76	heat shock protein family A (Hsp70) member 5	Homo sapiens	16-19
29035636-4	2018	The effects of acid concentration, cellulase and beta-glucosidase on total and ammonium nitrogen were studied with analysis indicating that higher acid concentrations increased nitrogen compounds with ammonium concentrations ranging from 0.20 to 1.24 g L-1 while enzymatic treatments did not significantly increase nitrogen levels.	Nitrogen	88-96	LOC547491	Glycine max	49-65
29035636-4	2018	The effects of acid concentration, cellulase and beta-glucosidase on total and ammonium nitrogen were studied with analysis indicating that higher acid concentrations increased nitrogen compounds with ammonium concentrations ranging from 0.20 to 1.24 g L-1 while enzymatic treatments did not significantly increase nitrogen levels.	Nitrogen	177-185	LOC547491	Glycine max	49-65
29989423-0	2018	Highly effective biosynthesis of N-acetylated human thymosin beta4 (Tbeta4) in Escherichia coli.	Nitrogen	33-34	thymosin beta 4 X-linked	Homo sapiens	52-66
30637701-6	2018	The sequence of DPMS in some species also carries a protein N-glycosylation motif (Asn-X-Ser/Thr).	Nitrogen	60-61	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Bos taurus	16-20
30637701-9	2018	In fact, overexpression of DPMS in capillary endothelial cells supports increased N-glycosylation, cellular proliferation, and enhanced chemotactic activity.	Nitrogen	82-83	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Bos taurus	27-31
29989423-0	2018	Highly effective biosynthesis of N-acetylated human thymosin beta4 (Tbeta4) in Escherichia coli.	Nitrogen	33-34	thymosin beta 4 X-linked	Homo sapiens	68-74
29989423-1	2018	Thymosin beta4 (Tbeta4) is a multifunctional N-acetylated peptide with distinct activities important at various stages.	Nitrogen	45-46	thymosin beta 4 X-linked	Homo sapiens	0-14
29989423-1	2018	Thymosin beta4 (Tbeta4) is a multifunctional N-acetylated peptide with distinct activities important at various stages.	Nitrogen	45-46	thymosin beta 4 X-linked	Homo sapiens	16-22
29126730-10	2018	Compared with the fluoroethyl derivative 1a, the carbazole N-atom of the fluoroisopropyl derivative 13a (Ki(CB2) = 2.9 nM) is better shielded against the attack of CYP enzymes as formation of N-oxides was not observed and N-dealkylation took place to a less amount.	Nitrogen	59-60	cannabinoid receptor 2 (macrophage)	Mus musculus	108-111
29174509-4	2018	Results from RNA analogs containing 7-deazaguanosine, 2-aminopurine and inosine confirm the importance of guanine N7, O6 and N2, respectively, in TLR8 activation.	Nitrogen	125-127	toll like receptor 8	Homo sapiens	146-150
29493463-2	2018	Excessive formation of reactive oxygen species (ROS) and nitrogen (RNSs) can overburden the ability of the enzymatic antioxidant defense mechanisms (superoxide dismutase, catalase and glutathione reductase) and non-enzymatic (uric acid, ascorbic acid, alpha-tocopherol and reduced glutathione), causing the development of oxidative stress, and consequently, impairing the neuronal system cells by means of oxidative damage to a variety of important biological molecules such as lipids, DNA and proteins.	Nitrogen	57-65	catalase	Homo sapiens	171-179
29146600-9	2018	CONCLUSIONS: Higher HbA1c in type 1 diabetes is associated with changes in the serum N-glycome that have elsewhere been shown to regulate the epidermal growth factor receptor and transforming growth factor-beta pathways that are implicated in DKD.	Nitrogen	2-3	epidermal growth factor receptor	Homo sapiens	142-174
28729031-5	2018	Renal dysfunction (elevated serum creatinine and blood urea nitrogen) and glomerular/tubular lesions were observed in these Uox-knockout mice.	Nitrogen	60-68	urate oxidase	Mus musculus	124-127
29113979-9	2018	Substitution of the basic amino acid repeats in the Ure2 relief sequence or phosphomimetic aspartate substitutions for the serine residues between them abolishes nuclear Gln3-Myc13 localization in response to both limiting nitrogen and rapamycin treatment.	Nitrogen	223-231	glutathione peroxidase	Saccharomyces cerevisiae S288C	52-56
29113979-12	2018	At least one general step that is associated with the Ure2 relief sequence may be prerequisite for responses to the specific stimuli of growth in poor nitrogen sources and rapamycin inhibition of TorC1.	Nitrogen	151-159	glutathione peroxidase	Saccharomyces cerevisiae S288C	54-58
28985138-4	2018	RESULTS: Utilization of soy milk in yogurt production decreased acidity, redox potential (Eh), total solids (TS), fat, total nitrogen, ash, total volatile fatty acids (TVFAs), saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and total amino acids contents.	Nitrogen	125-133	Weaning weight-maternal milk	Bos taurus	28-32
29095570-6	2018	Together with previous results, this structure suggests a common proton relay network shared by Class A beta-lactamases and PBPs, from the catalytic serine to the lysine, and ultimately to the ring nitrogen.	Nitrogen	198-206	amyloid beta precursor protein	Homo sapiens	102-108
28753183-7	2018	Changes in the ratios of n-6/n-3 and AA/docosahexaenoic acid from day 2 to 4 months together with infants" weight and feeding modality determined 55% of the variability of delta-IGF-1.	Nitrogen	3-4	insulin like growth factor 1	Homo sapiens	178-183
28643274-4	2018	A type 2 serum transferrin isoelectrofocusing and hypoglycosylation of apoCIII pointed to a combined N- and O-glycosylation defect.	Nitrogen	101-102	transferrin	Homo sapiens	15-26
31131224-3	2018	Also, progression of the prostate tumor is associated with activation of N-acetylglucosaminyltransferase-V (MGAT5)-mediated N-glycosylation of pro-metastatic proteins, including matriptase and integrins, followed by their enhanced retention at the cell surface.	Nitrogen	73-74	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	108-113
29188558-4	2018	In this Chapter, we discuss recent structure-based drug design projects that led to the discovery of: (a) novel A3AR agonists based on a highly rigidified (N)-methanocarba scaffold for the treatment of chronic neuropathic pain and other conditions, (b) fluorescent probes of the ARs and P2Y14R, as chemical tools for structural probing of these GPCRs and for improving assay capabilities, and (c) new more drug-like antagonists of the inflammation-related P2Y14R.	Nitrogen	155-158	adenosine A3 receptor	Homo sapiens	112-116
27643667-3	2018	MPO has five N-linked glycosylation sites on its heavy chains.	Nitrogen	13-14	myeloperoxidase	Homo sapiens	0-3
29230050-4	2018	In the presynaptic terminal, Munc13-1 molecules form multiple and discrete supramolecular self-assemblies that serve as independent vesicular release sites by recruiting syntaxin-1, a soluble N-ethylmaleimide-sensitive-factor attachment receptor (SNARE) protein essential for synaptic vesicle exocytosis.	Nitrogen	192-193	unc-13 homolog A	Homo sapiens	29-37
29466800-11	2018	RESULTS: The sulforaphane-induced Nrf2-HO-1/NQO-1 signaling pathway activation, as demonstrated by immunohistochemical and Western blot analyses, delayed the progression of serum creatinine and blood urea nitrogen, particularly lowering the 24-hour urinary protein levels of CRAD.	Nitrogen	205-213	NFE2 like bZIP transcription factor 2	Rattus norvegicus	34-38
29466800-11	2018	RESULTS: The sulforaphane-induced Nrf2-HO-1/NQO-1 signaling pathway activation, as demonstrated by immunohistochemical and Western blot analyses, delayed the progression of serum creatinine and blood urea nitrogen, particularly lowering the 24-hour urinary protein levels of CRAD.	Nitrogen	205-213	NAD(P)H quinone dehydrogenase 1	Rattus norvegicus	44-49
29964562-3	2017	The NO3- was derived mainly from the mixed sources according to the ranges of NO3-/Cl-, delta15 N-NO3-, and delta18O-NO3-.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	78-81
29111719-3	2017	In the course of drug discovery targeting Pim1, six benzofuranone-class inhibitors were found to differ only in the position of the indole-ring nitrogen atom.	Nitrogen	144-152	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	42-46
29263309-1	2017	C5a receptor 1 (C5aR1) is a G protein-coupled receptor for C5a and also an N-linked glycosylated protein.	Nitrogen	75-76	complement C5a receptor 1	Homo sapiens	16-21
30067454-3	2018	Both [Ca2+]C and [Ca2+]N were sensitively modulated by the inhibitors of calmodulin and protein kinases, supporting the view that calmodulin suppresses the 1st peaks and and protein kinases enhance 2nd peaks in [Ca2+]C and [Ca2+]N.	Nitrogen	23-24	calmodulin	Nicotiana tabacum	73-83
30067454-3	2018	Both [Ca2+]C and [Ca2+]N were sensitively modulated by the inhibitors of calmodulin and protein kinases, supporting the view that calmodulin suppresses the 1st peaks and and protein kinases enhance 2nd peaks in [Ca2+]C and [Ca2+]N.	Nitrogen	23-24	calmodulin	Nicotiana tabacum	130-140
29502530-10	2017	Trends were seen for improved grip strength and a reduction in C-Reactive Protein (CRP), Angiotensin II to Angiotensin 1-7 ratio and Interleukin-10, with no change in DNA n-methylation.	Nitrogen	3-4	C-reactive protein	Homo sapiens	63-81
29502530-10	2017	Trends were seen for improved grip strength and a reduction in C-Reactive Protein (CRP), Angiotensin II to Angiotensin 1-7 ratio and Interleukin-10, with no change in DNA n-methylation.	Nitrogen	3-4	C-reactive protein	Homo sapiens	83-86
29502530-10	2017	Trends were seen for improved grip strength and a reduction in C-Reactive Protein (CRP), Angiotensin II to Angiotensin 1-7 ratio and Interleukin-10, with no change in DNA n-methylation.	Nitrogen	3-4	angiotensinogen	Homo sapiens	89-103
30966035-5	2017	According to X-ray photoelectron spectroscopy (XPS), after immobilization of PRP, up to 10.7 at % of nitrogen was incorporated into the nanofibers surface confirming the grafting of proteins.	Nitrogen	101-109	complement component 4 binding protein alpha	Homo sapiens	77-80
29166025-1	2017	Copper(II)-catalyzed cross-coupling of anilines, methyl arenes, and TMSN3 in the presence of tert-butylhydroperoxide at moderate temperature produced 2-aryl benzimidazoles via a tandem C(sp3/sp2)-H functionalization and C-N bond formations.	Nitrogen	71-72	Sp2 transcription factor	Homo sapiens	191-194
29200268-1	2017	Despite the long history of SN2 reactions between nitrogen nucleophiles and alkyl electrophiles, many such substitution reactions remain out of reach.	Nitrogen	50-58	solute carrier family 38 member 5	Homo sapiens	28-31
28975712-6	2017	The N-nonyl analogue 35 b displayed a Ki value of &lt;&lt;14 nm for GBA1 inhibition and a Ki of 43 nm for GBA2.	Nitrogen	4-5	glucosylceramidase beta 2	Homo sapiens	106-110
29964577-2	2017	The results indicated that when ammonia increased to 1200 mg L-1, the MAAOB still maintained good nitrogen removal capability, though there was a slight inhibitory effect.	Nitrogen	98-106	immunoglobulin kappa variable 1-16	Homo sapiens	61-64
29292764-3	2017	The e-nose detects less than 1 molecule of TNT out of 10+12 N2 molecules in a carrier gas in 1 s. Differently silanized sensors give different responses to different molecules.	Nitrogen	60-62	chromosome 16 open reading frame 82	Homo sapiens	43-46
29964562-3	2017	The NO3- was derived mainly from the mixed sources according to the ranges of NO3-/Cl-, delta15 N-NO3-, and delta18O-NO3-.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	78-81
29964562-3	2017	The NO3- was derived mainly from the mixed sources according to the ranges of NO3-/Cl-, delta15 N-NO3-, and delta18O-NO3-.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	78-81
29964562-7	2017	NH4+-N and delta15 N-NO3- increased with decreasing NO3- and Cl- in EDR and LR during the wet season, which indicated denitrification processes occurred.	Nitrogen	0-1	NBL1, DAN family BMP antagonist	Homo sapiens	52-55
29964562-7	2017	NH4+-N and delta15 N-NO3- increased with decreasing NO3- and Cl- in EDR and LR during the wet season, which indicated denitrification processes occurred.	Nitrogen	5-6	NBL1, DAN family BMP antagonist	Homo sapiens	52-55
29181469-5	2017	Importantly, the synergy of all the parts of the n-p-n double heterojuctions plays an important role in interface band structure regulation for the enhancement of the photocatalytic properties of Er3+-doped Zn/Cu/Al-MPO.	Nitrogen	7-8	myeloperoxidase	Homo sapiens	216-219
29207575-0	2017	Synthesis of Novel Nitrogen-Containing Heterocycle Bromophenols and Their Interaction with Keap1 Protein by Molecular Docking.	Nitrogen	19-27	kelch like ECH associated protein 1	Homo sapiens	91-96
29594532-0	2017	Inner filter effect based fluorometric determination of the activity of alkaline phosphatase by using carbon dots codoped with boron and nitrogen.	Nitrogen	137-145	alkaline phosphatase, placental	Homo sapiens	72-92
29594532-9	2017	Graphical abstract Schematic of an inner filter effect based probe for alkaline phosphatase based on the use boron and nitrogen co-doped carbon dots (N/B-C-dots) modified with beta-cyclodextrin (beta-CD).	Nitrogen	119-127	alkaline phosphatase, placental	Homo sapiens	71-91
28888950-2	2017	AOX catalyzes the oxidative hydroxylation of substrates including several aliphatic and aromatic aldehydes, and nitrogen-containing heterocyclic compounds.	Nitrogen	112-120	aldehyde oxidase 1	Homo sapiens	0-3
28871315-2	2017	Multiday incubations of effluent collected from the Branford and New Haven, Connecticut, waste water treatment plants (WWTP) revealed low but steady conversion of organic nitrogen to nitrate (NO3-).	Nitrogen	171-179	NBL1, DAN family BMP antagonist	Homo sapiens	192-195
28511131-8	2017	N-linked glycosylation site (NGS) analysis revealed a novel potential NGS at GP5 amino acid position 59 in two of the subgroup 2 Henan isolates.	Nitrogen	0-1	glycoprotein V platelet	Homo sapiens	77-80
28145580-8	2017	Orai1 and Stim1, two N-glycosylated proteins, are involved in Store-Operated Calcium Entry (SOCE), and are essential for breast tumor cell migration.	Nitrogen	21-22	stromal interaction molecule 1	Homo sapiens	10-15
28956227-3	2017	NTPDase3/CD39L3is dominantly expressed in pancreatic islet cells, where it may regulate insulin secretion, and has seven N-linked glycosylation sites with four close to five highly conserved domains called "apyrase conserved regions" (ACRs).	Nitrogen	0-1	insulin	Homo sapiens	88-95
29262881-3	2017	The exression of NS and signal molecules of PI3K/AKT/mTOR pathway were detected by Western blot.	Nitrogen	17-19	AKT serine/threonine kinase 1	Homo sapiens	49-52
29236021-4	2017	The maximum ammonium removal of five times the amount of ammonium adsorbed was achieved when 1.0 muM OHHL was added at the C/N ratio of 7 (the bio-regeneration rate was up to 88.32%), which was 1.24-2.02 times the ammonium removal amount at C/N ratios of 3, 5, 9.	Nitrogen	125-126	latexin	Homo sapiens	97-100
29236021-4	2017	The maximum ammonium removal of five times the amount of ammonium adsorbed was achieved when 1.0 muM OHHL was added at the C/N ratio of 7 (the bio-regeneration rate was up to 88.32%), which was 1.24-2.02 times the ammonium removal amount at C/N ratios of 3, 5, 9.	Nitrogen	243-244	latexin	Homo sapiens	97-100
29236023-4	2017	Batch tests with AGS from the pilot reactor verified that at the greatest COD/N ratio (1.55), the N2O production (1.08 mgN2O-N L-1) and consumption (up to 0.05 mgN2O-N L-1), resulted in the lowest remaining dissolved N2O (0.03 mgN2O-N L-1), stripping the minimum N2O gas (0.018 mgN2O-N L-1).	Nitrogen	78-79	L1 cell adhesion molecule	Homo sapiens	127-130
29262881-3	2017	The exression of NS and signal molecules of PI3K/AKT/mTOR pathway were detected by Western blot.	Nitrogen	17-19	mechanistic target of rapamycin kinase	Homo sapiens	53-57
29209321-4	2017	It is plausible that these two dietary nitrogen sources would yield distinct immunological outcomes since proteins are recognized by the immune system as antigens and amino acids do not bind to antigen-recognition receptors but instead to intracellular receptors such as mammalian target of rapamycin (mTOR).	Nitrogen	39-47	mechanistic target of rapamycin kinase	Homo sapiens	271-300
29185502-1	2017	Nitrogen (N) as a nutrient, in the form of nitrate (NO3-), is essential for plant growth.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	52-55
29169396-6	2017	For the APOE SNP rs1064725, only TT homozygotes showed a significant reduction in total cholesterol after the MUFA diet (n = 33; -0.71 +- 1.88 mmol/l) compared to the SFA (n = 38; 0.34 +- 0.55 mmol/l) or n-6 PUFA diets (n = 37; -0.08 +- 0.73 mmol/l) (P = 0.004).	Nitrogen	29-30	apolipoprotein E	Homo sapiens	8-12
29109265-0	2017	Diminished Ost3-dependent N-glycosylation of the BiP nucleotide exchange factor Sil1 is an adaptive response to reductive ER stress.	Nitrogen	26-27	Sil1p	Saccharomyces cerevisiae S288C	80-84
29109265-3	2017	Both Sil1 and Lhs1 are glycoproteins, but how N-glycosylation regulates their function is not known.	Nitrogen	46-47	Sil1p	Saccharomyces cerevisiae S288C	5-9
29109265-4	2017	Here, we show that N-glycosylation of Sil1, but not of Lhs1, is diminished upon reductive stress.	Nitrogen	19-20	Sil1p	Saccharomyces cerevisiae S288C	38-42
29109265-5	2017	N-glycosylation of Sil1 is predominantly Ost3-dependent and requires a functional Ost3 CxxC thioredoxin motif.	Nitrogen	0-1	Sil1p	Saccharomyces cerevisiae S288C	19-23
29109265-7	2017	Unglycosylated Sil1 is not only functional but is more effective at rescuing loss of Lhs1 activity than N-glycosylated Sil1.	Nitrogen	104-105	Sil1p	Saccharomyces cerevisiae S288C	15-19
29109265-7	2017	Unglycosylated Sil1 is not only functional but is more effective at rescuing loss of Lhs1 activity than N-glycosylated Sil1.	Nitrogen	104-105	Sil1p	Saccharomyces cerevisiae S288C	119-123
29109265-9	2017	We propose that reductive stress in the ER inhibits the Ost3-dependent N-glycosylation of Sil1, which regulates specific BiP functions appropriate to the needs of the ER under reductive stress.	Nitrogen	71-72	Sil1p	Saccharomyces cerevisiae S288C	90-94
29209321-4	2017	It is plausible that these two dietary nitrogen sources would yield distinct immunological outcomes since proteins are recognized by the immune system as antigens and amino acids do not bind to antigen-recognition receptors but instead to intracellular receptors such as mammalian target of rapamycin (mTOR).	Nitrogen	39-47	mechanistic target of rapamycin kinase	Homo sapiens	302-306
29250408-2	2017	Each CoII ion is coordinated by two pyridine N atoms from two bridging L ligands, two O atoms from methanol mol-ecules and two chloride anions, all inversion-related.	Nitrogen	45-46	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	5-9
28482461-4	2017	At an initial ZVI1.5 concentrations of 0.832g/L, and an optimal initial pH of 1.62, the NO3- concentration was reduced by 95% from 12.50mg/L-N to 0.65mg/L-N, in 120min.	Nitrogen	141-142	NBL1, DAN family BMP antagonist	Homo sapiens	88-91
28822969-12	2017	The present study shows that NS-1619-induced oxidant production prevents ischemia-reperfusion-induced inflammation and mucosal barrier disruption in the small intestine by provoking increases in heme oxygenase-1 activity.	Nitrogen	29-31	heme oxygenase 1	Mus musculus	195-211
29038805-7	2017	The CoIII centre is octahedrally coordinated by the six nitrogen atoms of the deprotonated organic ligands in a facial arrangement.	Nitrogen	56-64	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-9
28957768-4	2017	This radical can selectively transform ammonia nitrogen to N2 (79.9%) and NO3- (19.2%), similar to the breakpoint chlorination reaction.	Nitrogen	47-55	NBL1, DAN family BMP antagonist	Homo sapiens	74-77
28936578-5	2017	In cave waters, the oxidised form of nitrogen NO3- predominates; in surface waters in the vicinity, unoxidised forms prevail: NH4+, NH3, and NH4SO4-.	Nitrogen	37-45	NBL1, DAN family BMP antagonist	Homo sapiens	46-49
29152374-2	2017	The CoII cations are coordinated by two terminal N-bonding thio-cyanate anions and four N-bonding pyridine-4-carbo-thio-amide ligands, resulting in discrete and slightly distorted octa-hedral complexes.	Nitrogen	49-50	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
28597972-3	2017	Using the membrane-based split ubiquitin yeast two-hybrid system (MYTH) and a human liver cDNA library, we obtained the human GLP-1R interactome and identified SERP1 as a potential interacting protein based on its ability to stabilize membrane proteins and facilitate N-linked glycosylation.	Nitrogen	92-93	stress associated endoplasmic reticulum protein 1	Homo sapiens	160-165
28913653-6	2017	When exposed to added Al3+, the proportion of inorganic N acquired as NO3- dropped 14% across species, but we did not detect a reduction in overall N uptake, nor did tree species differ in this response.	Nitrogen	56-57	NBL1, DAN family BMP antagonist	Homo sapiens	70-73
28784321-2	2017	In this study, the roles of YHM2, ODC1 and ODC2 in the assimilation of nitrogen and in the biosynthesis of lysine have been investigated.	Nitrogen	71-79	mitochondrial 2-oxodicarboxylate carrier	Saccharomyces cerevisiae S288C	34-38
28738638-2	2017	Herein, we reported an anti-interfere ability enhanced luminescent sensor of lanthanide metal-organic framework (Ln-MOF) filled mixed matrix membranes (MMMs), which combining the processibility of poly(methyl methacrylate) (PMMA) polymer with Ln-MOF of {[Tb2(AIP)2(H2O)10] (AIP) 4H2O}n (Tb-AIP, where AIP is 5-aminoisophthalate) fillers.	Nitrogen	5-6	WW domain containing E3 ubiquitin protein ligase 2	Homo sapiens	255-264
29163579-2	2017	Here, pah1 pah2 double-knockout mutants were found to be hypersensitive to nitrogen (N) starvation, whereas transgenic plants overexpressing PAH1 or PAH2 in the pah1 pah2 mutant background showed a similar growth phenotype as compared with wild type (WT) under N starvation.	Nitrogen	75-83	Lipin family protein	Arabidopsis thaliana	6-10
29152374-2	2017	The CoII cations are coordinated by two terminal N-bonding thio-cyanate anions and four N-bonding pyridine-4-carbo-thio-amide ligands, resulting in discrete and slightly distorted octa-hedral complexes.	Nitrogen	88-89	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
29163579-2	2017	Here, pah1 pah2 double-knockout mutants were found to be hypersensitive to nitrogen (N) starvation, whereas transgenic plants overexpressing PAH1 or PAH2 in the pah1 pah2 mutant background showed a similar growth phenotype as compared with wild type (WT) under N starvation.	Nitrogen	75-83	phosphatidic acid phosphohydrolase 2	Arabidopsis thaliana	11-15
29163579-5	2017	Pulse-chase labeling experiments using plants grown under N-depleted conditions showed that, in pah1 pah2 plants, the labeling percent of chloroplast lipids such as phosphatidylglycerol and monogalactosyldiacylglycerol in the total glycerolipids was significantly lower than in WT.	Nitrogen	58-59	Lipin family protein	Arabidopsis thaliana	96-100
29079776-9	2017	In concert with GCN2, TOR allows photo-autotrophic eukaryotes to coordinate the fluxes of carbon, nitrogen, and sulfur for efficient cysteine biosynthesis under varying external nutrient supply.	Nitrogen	98-106	target of rapamycin	Arabidopsis thaliana	22-25
29163579-5	2017	Pulse-chase labeling experiments using plants grown under N-depleted conditions showed that, in pah1 pah2 plants, the labeling percent of chloroplast lipids such as phosphatidylglycerol and monogalactosyldiacylglycerol in the total glycerolipids was significantly lower than in WT.	Nitrogen	58-59	phosphatidic acid phosphohydrolase 2	Arabidopsis thaliana	101-105
29163579-6	2017	Moreover, N starvation-induced degradation of chloroplast structure was enhanced in pah1 pah2 mutants, and the membrane structure was recovered by complementation with PAH1.	Nitrogen	10-11	Lipin family protein	Arabidopsis thaliana	84-88
29163579-6	2017	Moreover, N starvation-induced degradation of chloroplast structure was enhanced in pah1 pah2 mutants, and the membrane structure was recovered by complementation with PAH1.	Nitrogen	10-11	phosphatidic acid phosphohydrolase 2	Arabidopsis thaliana	89-93
29163579-6	2017	Moreover, N starvation-induced degradation of chloroplast structure was enhanced in pah1 pah2 mutants, and the membrane structure was recovered by complementation with PAH1.	Nitrogen	10-11	Lipin family protein	Arabidopsis thaliana	168-172
28930437-5	2017	The most commonly encountered structures, C- and N-metalated nitriles, have either sp3 or sp2 hybridization at the nucleophilic carbon, which essentially translates into two distinct organometallic species with similar but nonidentical stereoselectivity, regioselectivity, and reactivity preferences.	Nitrogen	49-50	Sp3 transcription factor	Homo sapiens	83-86
29061956-2	2017	Most oxycodone is metabolized by N-demethylation to noroxycodone by CYP3A.	Nitrogen	33-34	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	68-73
28887418-9	2017	Our results provide new information regarding the function of the lmo0325-lmo0327 locus in L. monocytogenes and link it to the expression of chitinolytic activity.IMPORTANCE Many bacteria from terrestrial and marine environments express chitinase activities enabling them to utilize chitin as the sole source of carbon and nitrogen.	Nitrogen	323-331	lmo0327	Listeria monocytogenes EGD-e	74-81
29033328-7	2017	In plants, the major mechanism of NO synthesis is via NITRATE REDUCTASE (NR), an enzyme of nitrogen assimilation [5].	Nitrogen	91-99	nitrate reductase 1	Arabidopsis thaliana	54-71
29033328-7	2017	In plants, the major mechanism of NO synthesis is via NITRATE REDUCTASE (NR), an enzyme of nitrogen assimilation [5].	Nitrogen	91-99	nitrate reductase 1	Arabidopsis thaliana	73-75
29045410-7	2017	As previously reported for men, time to peak diversity in env-gp120 in women was positively associated with time to CD4+ cell count below 200 (P = 0.017), and the number of predicted N-linked glycosylation sites generally increased over time, followed by a plateau or decline, with the majority of changes localized to the V1-V2 region.	Nitrogen	183-184	endogenous retrovirus group W member 1, envelope	Homo sapiens	58-61
28930437-5	2017	The most commonly encountered structures, C- and N-metalated nitriles, have either sp3 or sp2 hybridization at the nucleophilic carbon, which essentially translates into two distinct organometallic species with similar but nonidentical stereoselectivity, regioselectivity, and reactivity preferences.	Nitrogen	49-50	Sp2 transcription factor	Homo sapiens	90-93
29038579-0	2017	Synthesis of single-phase L10-FeNi magnet powder by nitrogen insertion and topotactic extraction.	Nitrogen	52-60	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	26-29
29038579-2	2017	In this study, single-phase L10-FeNi powder with a high degree of order was synthesized through a new method, nitrogen insertion and topotactic extraction (NITE).	Nitrogen	110-118	immunoglobulin kappa variable 3-7 (non-functional)	Homo sapiens	28-31
28872308-0	2017	Copper-Catalyzed Dehydrogenative C(sp2)-N Bond Formation via Direct Oxidative Activation of an Anilidic N-H Bond: Synthesis of Benzoimidazo[1,2-a]indoles.	Nitrogen	40-41	Sp2 transcription factor	Homo sapiens	33-38
29965215-3	2017	The results showed that when the influent ammonia nitrogen concentration was 917-1540 mg L-1, the residual ammonia nitrogen concentration of 6 mg L-1 can be used as the control parameter to meet the requirements of process stability but the ammonia nitrogen sensor had many problems such as high costs and large errors.	Nitrogen	50-58	immunoglobulin kappa variable 1-16	Homo sapiens	89-92
29965215-3	2017	The results showed that when the influent ammonia nitrogen concentration was 917-1540 mg L-1, the residual ammonia nitrogen concentration of 6 mg L-1 can be used as the control parameter to meet the requirements of process stability but the ammonia nitrogen sensor had many problems such as high costs and large errors.	Nitrogen	50-58	immunoglobulin kappa variable 1-16	Homo sapiens	146-149
29965215-3	2017	The results showed that when the influent ammonia nitrogen concentration was 917-1540 mg L-1, the residual ammonia nitrogen concentration of 6 mg L-1 can be used as the control parameter to meet the requirements of process stability but the ammonia nitrogen sensor had many problems such as high costs and large errors.	Nitrogen	115-123	immunoglobulin kappa variable 1-16	Homo sapiens	89-92
29965215-3	2017	The results showed that when the influent ammonia nitrogen concentration was 917-1540 mg L-1, the residual ammonia nitrogen concentration of 6 mg L-1 can be used as the control parameter to meet the requirements of process stability but the ammonia nitrogen sensor had many problems such as high costs and large errors.	Nitrogen	115-123	immunoglobulin kappa variable 1-16	Homo sapiens	146-149
28970495-5	2017	We structurally delineate the CD22 site targeted by the therapeutic antibody epratuzumab at 3.1 A resolution and determine a critical role for CD22 N-linked glycosylation in antibody engagement.	Nitrogen	148-149	CD22 molecule	Homo sapiens	143-147
29053695-3	2017	STIM1 undergoes post-translational N-glycosylation at two luminal Asn sites within the Ca2+ sensing domain of the molecule.	Nitrogen	35-36	stromal interaction molecule 1	Homo sapiens	0-5
29053695-4	2017	However, the biochemical, biophysical, and structure biological effects of N-glycosylated STIM1 were poorly understood until recently due to an inability to readily obtain high levels of homogeneous N-glycosylated protein.	Nitrogen	75-76	stromal interaction molecule 1	Homo sapiens	90-95
28972974-1	2017	Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including adenylylation of some or all of the twelve subunits by adenylyl transferase.	Nitrogen	55-63	glutamate-ammonia ligase	Homo sapiens	0-20
28689147-1	2017	Quantitative identification of nitrate (NO3--N) sources is critical to the control of nonpoint source nitrogen pollution in an agricultural watershed.	Nitrogen	102-110	NBL1, DAN family BMP antagonist	Homo sapiens	40-43
28694218-7	2017	N-terminal sequencing and MALDI-ToF mass spectrometry revealed that rHGL was produced in its mature form, with a global mass of 50,837+-32Da corresponding to a N-glycosylated form of HGL polypeptide (43,193Da).	Nitrogen	0-1	lipase F, gastric type	Homo sapiens	69-72
28622649-1	2017	Inorganic nitrogen contaminants (INC) (NH4+, NO3-, NO2-, NH3, NO, NO2, and N2O) pose a growing risk to the environment, and their remediation methods are highly sought after.	Nitrogen	10-18	NBL1, DAN family BMP antagonist	Homo sapiens	45-48
28689147-3	2017	Results showed that NO3--N was the main form of nitrogen in this watershed, accounting for approximately 74% of the total nitrogen concentration.	Nitrogen	48-56	NBL1, DAN family BMP antagonist	Homo sapiens	20-23
28689147-3	2017	Results showed that NO3--N was the main form of nitrogen in this watershed, accounting for approximately 74% of the total nitrogen concentration.	Nitrogen	122-130	NBL1, DAN family BMP antagonist	Homo sapiens	20-23
28774774-9	2017	Therefore, our results suggest that the three genes have a redundant activity in the S. cerevisiae N-linked glycosylation pathway, but KTR4 plays a major role in O-linked glycan synthesis.	Nitrogen	99-100	putative mannosyltransferase	Saccharomyces cerevisiae S288C	135-139
28803068-6	2017	Complex-type oligosaccharides dominated the N-glycosylation pattern of hIFNgamma-HEK with some terminal sialylation and core fucosylation.	Nitrogen	44-45	interferon gamma	Homo sapiens	71-80
28774774-0	2017	Saccharomyces cerevisiae KTR4, KTR5 and KTR7 encode mannosyltransferases differentially involved in the N- and O-linked glycosylation pathways.	Nitrogen	104-105	putative mannosyltransferase	Saccharomyces cerevisiae S288C	25-29
28855383-0	2017	Expression of Concern: N-terminal palmitoylation within the appropriate amino acid environment conveys on NOS2 the ability to progress along the intracellular sorting pathways.	Nitrogen	23-24	nitric oxide synthase 2	Homo sapiens	106-110
28920975-1	2017	Correction for "Visible-light-enhanced power generation in microbial fuel cells coupling with 3D nitrogen-doped graphene" by Dan Guo et al., Chem.	Nitrogen	97-105	NBL1, DAN family BMP antagonist	Homo sapiens	125-128
28947017-9	2017	This mutation abolishes the N-glycosylation site in position 83 of the mature AAT.	Nitrogen	28-29	serpin family A member 1	Homo sapiens	78-81
28728105-8	2017	Molecular docking revealed that the nitrogen atom of imidazopyridines and the oxygen atom of the phenoxypropyl linker were involved in hydrogen bound interactions with Asp228 and Asp32 of BACE1 active site, respectively.	Nitrogen	36-44	beta-secretase 1	Homo sapiens	188-193
28315854-0	2017	Mutation of N-linked glycosylation in EpCAM affected cell adhesion in breast cancer cells.	Nitrogen	12-13	epithelial cell adhesion molecule	Homo sapiens	38-43
28315854-4	2017	The results showed that EpCAM expression was associated with cell adhesion and N-glycosylation mutation of EpCAM decreased adhesion capacity.	Nitrogen	79-80	epithelial cell adhesion molecule	Homo sapiens	24-29
28315854-4	2017	The results showed that EpCAM expression was associated with cell adhesion and N-glycosylation mutation of EpCAM decreased adhesion capacity.	Nitrogen	79-80	epithelial cell adhesion molecule	Homo sapiens	107-112
28315854-5	2017	N-glycosylation mutation of EpCAM was correlated with lower levels of integrin beta1 and fibronectin.	Nitrogen	0-1	epithelial cell adhesion molecule	Homo sapiens	28-33
28315854-5	2017	N-glycosylation mutation of EpCAM was correlated with lower levels of integrin beta1 and fibronectin.	Nitrogen	0-1	fibronectin 1	Homo sapiens	89-100
28315854-6	2017	We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3beta/beta-catenin signaling pathway, which further adjusted MMP2/9 expression and activities.	Nitrogen	29-30	epithelial cell adhesion molecule	Homo sapiens	48-53
28315854-6	2017	We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3beta/beta-catenin signaling pathway, which further adjusted MMP2/9 expression and activities.	Nitrogen	29-30	AKT serine/threonine kinase 1	Homo sapiens	93-96
28315854-8	2017	These data could potentially clarify molecular regulation of EpCAM by N-glycosylation and intensify our understanding of the utility of glycosylated EpCAM as a target for breast cancer therapy.	Nitrogen	70-71	epithelial cell adhesion molecule	Homo sapiens	61-66
28774774-0	2017	Saccharomyces cerevisiae KTR4, KTR5 and KTR7 encode mannosyltransferases differentially involved in the N- and O-linked glycosylation pathways.	Nitrogen	104-105	putative mannosyltransferase	Saccharomyces cerevisiae S288C	31-35
28961202-2	2017	N in its sp3, sp2 and sp hybridizations is taken as the electron-donating base.	Nitrogen	0-1	Sp3 transcription factor	Homo sapiens	9-12
28961202-2	2017	N in its sp3, sp2 and sp hybridizations is taken as the electron-donating base.	Nitrogen	0-1	Sp2 transcription factor	Homo sapiens	14-17
29018490-6	2017	In spite of the limited TLR4 activation with Pg-LPS, the TLR4 blocker eritoran decreased blood urea nitrogen and creatinine, and raised the survival rate of the Pg-LPS-administered diabetic mice slightly.	Nitrogen	100-108	toll-like receptor 4	Mus musculus	57-61
28979255-14	2017	The findings also suggest that simultaneous enhancement of nitrogen retention and N2O emission reduction may be feasible through pH modulation, but only in environments where C:N or NO2-:NO3- ratio does not exhibit overarching control over the NO3-/NO2- reduction pathways.	Nitrogen	59-67	NBL1, DAN family BMP antagonist	Homo sapiens	187-190
28979255-14	2017	The findings also suggest that simultaneous enhancement of nitrogen retention and N2O emission reduction may be feasible through pH modulation, but only in environments where C:N or NO2-:NO3- ratio does not exhibit overarching control over the NO3-/NO2- reduction pathways.	Nitrogen	59-67	NBL1, DAN family BMP antagonist	Homo sapiens	244-247
27692933-2	2017	The N-demethylation by CYP3A4/5 and the O-demethylation by CYP2D6 in human liver microsomes (HLM) followed Michaelis-Menten kinetics, with intrinsic clearances of 1.46muL/min/mg and 0.35muL/min/mg, respectively.	Nitrogen	4-5	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	23-29
29156678-4	2017	TUSC3 is a subunit of the oligosaccharyltransferase (OST) complex at the endoplasmic reticulum (ER) which catalyzes bulk N-glycosylation of membrane and secretory proteins.	Nitrogen	121-122	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	26-51
29156678-4	2017	TUSC3 is a subunit of the oligosaccharyltransferase (OST) complex at the endoplasmic reticulum (ER) which catalyzes bulk N-glycosylation of membrane and secretory proteins.	Nitrogen	121-122	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	53-56
28525865-3	2017	This bidentate ligand coordinates three metal ions of Co(II), Cu(II) and Fe(II) via nitrogen and oxygen atoms.	Nitrogen	84-92	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	54-60
28780317-4	2017	The isolated alphaR1P was N-glycosylated with different nitrogen bases (adenine, guanine and uracil) using PNPase or uridine phosphorylase (UPase) to give the corresponding ribonucleosides in high yield based on the glycosyl phosphate.	Nitrogen	26-27	purine nucleoside phosphorylase	Homo sapiens	107-113
28521205-2	2017	For this purpose, a novel silica-bipyridine multidentate functional adsorbent was synthesized by vacuum infusing a new asymmetric N-donor ligand CA-MTBP (bipyridine derivative) into the macroporous SiO2-P support.	Nitrogen	130-131	MDM2 binding protein	Homo sapiens	148-152
28751572-8	2017	However, black carbon, sulfate, and nitrogen oxides were negatively associated with fibrinogen, and sulfate was negatively associated with tumor necrosis factor alpha.	Nitrogen	36-44	fibrinogen beta chain	Homo sapiens	84-94
30023718-1	2017	Aldehyde oxidase (AO) is a molybdenum-containing enzyme involved in the clearance of drug compounds containing aldehydes and N-containing heterocyclic fragments.	Nitrogen	125-126	aldehyde oxidase 1	Homo sapiens	0-16
31966839-6	2017	Higher expression of nuclear CDK6 protein was significantly associated with N stage (P=0.012), clinical stage (P=0.008), and degree of differentiation (P=0.015), but there was no association with T stage (P=0.472) or distant metastasis (P=0.163).	Nitrogen	76-77	cyclin dependent kinase 6	Homo sapiens	29-33
28864905-2	2017	We present new three-dimensional pulse sequences for measurement of Carr-Purcell-Meiboom-Gill relaxation dispersions at backbone nitrogen and carbonyl positions.	Nitrogen	129-137	arrestin 3	Homo sapiens	68-72
28679684-3	2017	Although microarray studies have identified most nitrogen-sensitive genes, nitrogen-induced post-translational regulation has only been studied for very few proteins among which the general amino acid permease Gap1.	Nitrogen	75-83	amino acid permease GAP1	Saccharomyces cerevisiae S288C	210-214
28679684-4	2017	Adding a preferred nitrogen source to proline-grown cells triggers Gap1 endocytosis and vacuolar degradation in an Rsp5-Bul1/2-dependent manner.	Nitrogen	19-27	amino acid permease GAP1	Saccharomyces cerevisiae S288C	67-71
28478288-5	2017	In order to remove NO3--N completely from water, Cl- is added to help further oxidize NH4+-N to N2.	Nitrogen	96-98	NBL1, DAN family BMP antagonist	Homo sapiens	19-22
30023718-1	2017	Aldehyde oxidase (AO) is a molybdenum-containing enzyme involved in the clearance of drug compounds containing aldehydes and N-containing heterocyclic fragments.	Nitrogen	125-126	aldehyde oxidase 1	Homo sapiens	18-20
28674185-0	2017	Yeast RNA-Binding Protein Nab3 Regulates Genes Involved in Nitrogen Metabolism.	Nitrogen	59-67	Nab3p	Saccharomyces cerevisiae S288C	26-30
28674185-6	2017	In addition, we observe that nitrogen catabolite-repressed genes are upregulated by Nab3 depletion.	Nitrogen	29-37	Nab3p	Saccharomyces cerevisiae S288C	84-88
28808683-2	2017	We report copper-mediated formation of N-unsubstituted aliphatic imines from easily available aliphatic azides using a customized phenanthroline-based ligand (L1*).	Nitrogen	39-40	immunoglobulin kappa variable 1-16	Homo sapiens	159-162
28782778-2	2017	The presence of domains of conjugated sp2 carbon, which are formed upon carbonization of precursors at high temperature; nitrogen doping; and as recently shown, the presence of molecular fluorophores, are contributing to the emission of such CDs.	Nitrogen	121-129	Sp2 transcription factor	Homo sapiens	38-41
28288447-0	2017	Chemical redox modulated fluorescence of nitrogen-doped graphene quantum dots for probing the activity of alkaline phosphatase.	Nitrogen	41-49	alkaline phosphatase, placental	Homo sapiens	106-126
28288447-3	2017	In this work, on the basis of chemical redox strategy to modulate the fluorescence of nitrogen-doped graphene quantum dots (NGQDs), a novel label-free fluorescent sensing system for the detection of alkaline phosphatase (ALP) activity has been developed.	Nitrogen	86-94	alkaline phosphatase, placental	Homo sapiens	199-219
28288447-3	2017	In this work, on the basis of chemical redox strategy to modulate the fluorescence of nitrogen-doped graphene quantum dots (NGQDs), a novel label-free fluorescent sensing system for the detection of alkaline phosphatase (ALP) activity has been developed.	Nitrogen	86-94	alkaline phosphatase, placental	Homo sapiens	221-224
28617578-3	2017	We establish that MUC16 oncogenic effects are mediated through MGAT5-dependent N-glycosylation of two specific asparagine sites within its 58 amino acid ectodomain.	Nitrogen	79-80	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	63-68
28735024-0	2017	N-Linked Glycosylation of the p24 Family Protein p24delta5 Modulates Retrograde Golgi-to-ER Transport of K/HDEL Ligands in Arabidopsis.	Nitrogen	0-1	emp24/gp25L/p24 family/GOLD family protein	Arabidopsis thaliana	49-58
28735024-5	2017	Here, we show that Arabidopsis p24delta5 protein is N-glycosylated in its GOLD domain.	Nitrogen	52-53	emp24/gp25L/p24 family/GOLD family protein	Arabidopsis thaliana	31-40
28685570-2	2017	This cross-coupling reaction includes the oxidative cleavage of sp2 C-N bonds of phenyl hydrazides to form a phenyl radical and the subsequent N-addition to cyanos to form new sp2 C-N bonds and provides efficient access to various N-phenyl amides in moderate to good yields under mild reaction conditions.	Nitrogen	70-71	Sp2 transcription factor	Homo sapiens	64-67
29050309-4	2017	In addition, we also defined the N-glycosylation sites and N-glycans present on homo and porcine plasma fibronectin.	Nitrogen	33-34	fibronectin 1	Homo sapiens	104-115
29050309-5	2017	These N-glycosylation modifications of the plasma fibronectin synergistically support the integrin-mediated signals to bring about mediating cellular adhesion and directed cell migration.	Nitrogen	6-7	fibronectin 1	Homo sapiens	50-61
28485066-2	2017	The reaction proceeds through an oxidative C-N bond formation, followed by an intramolecular C(sp2 )-H bond functionalization/C-O cyclization in one pot.	Nitrogen	45-46	Sp2 transcription factor	Homo sapiens	93-98
32264215-6	2017	The grafting of beta-cyclodextrin (beta-CD) onto chitosan chains demonstrated remarkable cellular uptake (~5-fold) compared to pure chitosan at N/P = 6, attributed to a strong interaction and temporary disruption of the lipid bilayer in the cell membrane by the synthesized copolymer.	Nitrogen	144-145	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	35-42
28778164-21	2017	Serum level of total protein, albumin, globulin, nitrite, creatinine and blood urea nitrogen (BUN) was significantly increased (P &lt; 0.01) by CCl4 treatment.	Nitrogen	84-92	C-C motif chemokine ligand 4	Rattus norvegicus	144-148
28685570-2	2017	This cross-coupling reaction includes the oxidative cleavage of sp2 C-N bonds of phenyl hydrazides to form a phenyl radical and the subsequent N-addition to cyanos to form new sp2 C-N bonds and provides efficient access to various N-phenyl amides in moderate to good yields under mild reaction conditions.	Nitrogen	70-71	Sp2 transcription factor	Homo sapiens	176-179
28477543-11	2017	To prevent phytoplankton blooms with 20 mug L-1 chlorophyll-a throughout Lake Taihu, both phosphorus and nitrogen loads need a nearly 90% reduction.	Nitrogen	105-113	immunoglobulin kappa variable 1-16	Homo sapiens	44-47
28970919-7	2017	The presence of this hemilabile vicinal B-H   Ru interaction in (POBOP)Ru(H)(PPh3) was found to stabilize a latent coordination site at the metal center promoting efficient catalytic transfer dehydrogenation of cyclooctane under nitrogen and air at 170  C.	Nitrogen	229-237	caveolin 1	Homo sapiens	77-81
27271094-10	2017	There was a statistically significant interaction between APOA2 polymorphism and n-6 PUFA intake on 8-isoprostane F2alpha concentration as well as n-3 PUFA intake on serum SOD activity (p-interaction = 0.04 and 0.02, respectively).	Nitrogen	29-30	superoxide dismutase 1	Homo sapiens	172-175
28630087-1	2017	Human neutrophil elastase (HNE) is an important N-glycosylated serine protease in the innate immune system, but the structure and immune-modulating functions of HNE N-glycosylation remain undescribed.	Nitrogen	28-29	coagulation factor II, thrombin	Homo sapiens	63-78
28630087-12	2017	The heavily N-glycosylated HNE protease inhibitor, alpha1-antitrypsin, displayed concentration-dependent complex formation and preferred glycoform-glycoform interactions with HNE.	Nitrogen	12-13	serpin family A member 1	Homo sapiens	51-69
28390103-0	2017	ASN1-encoded asparagine synthetase in floral organs contributes to nitrogen filling in Arabidopsis seeds.	Nitrogen	67-75	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	0-4
28390103-4	2017	In the asn1 mutant, aberrant embryo cell divisions in upper suspensor cell layers from globular to heart stages assign a role for nitrogen in differentiating embryos within the ovary.	Nitrogen	130-138	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	7-11
28390103-6	2017	In transgenic Arabidopsis expressing promoterCaMV35S ::ASN1 fusion, marked metabolomics changes at stage 0, including a several-fold increase in free asparagine, are correlated to enhanced seed nitrogen.	Nitrogen	194-202	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	55-59
28390103-7	2017	However, specific promoterNapin2S ::ASN1 expression during seed formation and a six-fold increase in asparagine toward the desiccation stage result in wild-type seed nitrogen, underlining that delayed accumulation of asparagine impairs the timing of its use by releasing amide and amino nitrogen.	Nitrogen	166-174	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	36-40
28746350-0	2017	Differential effects of N-linked glycosylation of Vstm5 at multiple sites on surface expression and filopodia formation.	Nitrogen	24-25	V-set and transmembrane domain containing 5	Mus musculus	50-55
28746350-4	2017	Four N-linked glycosylation sites (Asn43, Asn87, Asn101, and Asn108) are predicted to be located in the extracellular N-terminus of mouse Vstm5.	Nitrogen	5-6	V-set and transmembrane domain containing 5	Mus musculus	138-143
28746350-6	2017	N-glycosylation at multiple sites affects differentially the function of Vstm5.	Nitrogen	0-1	V-set and transmembrane domain containing 5	Mus musculus	73-78
28746350-8	2017	These results indicate that N-linked glycosylation at multiple sites plays important roles by differentially influencing the expression, targeting, and biological activity of Vstm5.	Nitrogen	28-29	V-set and transmembrane domain containing 5	Mus musculus	175-180
28700571-3	2017	Although Env can tolerate a high degree of mutation in five variable regions (V1-V5), and also at N-linked glycosylation sites that contribute roughly half the mass of Env, the functional sites for recognition of receptor CD4 and co-receptor CXCR4/CCR5 are conserved and essential for viral fitness.	Nitrogen	98-99	CD4 molecule	Homo sapiens	222-225
28584151-6	2017	Resistance mapped to the loss of multiple potential N-linked glycosylation sites in gp120, suggesting that inhibition is due to steric hindrance of CD4-binding-induced conformational changes.	Nitrogen	52-53	CD4 molecule	Homo sapiens	148-151
28654284-3	2017	This structure is designed to mitigate the rapid decomposition of the radical via intramolecular 1,5-hydrogen atom transfer (1,5-HAT) that was observed in its constitutional isomer 1-H with four mPEG-3 groups in the vicinity of the nitrogen-centered radical (1- and 8-positions of TTBC).	Nitrogen	232-240	paternally expressed 3	Mus musculus	195-201
28678517-7	2017	This study thus provides insights into the interplay among FUT8, GnT-IV, and GnT-V in N-linked glycosylation during the assembly of glycoproteins.	Nitrogen	86-87	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	77-82
28587449-6	2017	Incubation of these guanine conjugates, as solids, with a decanoic acid vesicle suspension, showed that ether- and triazole-linked C10 anchors yielded an increased partitioning of the guanine derivative into the membranous phase compared to directly N-9-linked saturated alkyl anchors.	Nitrogen	250-251	homeobox C10	Homo sapiens	131-134
28724997-0	2017	Nitrogen-doped Carbon Dots Mediated Fluorescent on-off Assay for Rapid and Highly Sensitive Pyrophosphate and Alkaline Phosphatase Detection.	Nitrogen	0-8	alkaline phosphatase, placental	Homo sapiens	110-130
28724997-1	2017	In this report, a novel fluorescent sensing platform using nitrogen-doped carbon dots (N-CDs) as probes for fluorescence signal transmission has been designed for the detection of significant biomolecules pyrophosphate (PPi) and alkaline phosphatase (ALP).	Nitrogen	59-67	alkaline phosphatase, placental	Homo sapiens	229-249
28724997-1	2017	In this report, a novel fluorescent sensing platform using nitrogen-doped carbon dots (N-CDs) as probes for fluorescence signal transmission has been designed for the detection of significant biomolecules pyrophosphate (PPi) and alkaline phosphatase (ALP).	Nitrogen	59-67	alkaline phosphatase, placental	Homo sapiens	251-254
29179433-14	2017	Therefore, this study demonstrates, for the first time, that Skl regulates anti-oxidant GSH generation via interaction with FGH through N-glycosylation.	Nitrogen	136-137	esterase D	Homo sapiens	124-127
28471085-2	2017	Surprisingly, highly charged protein ions (HCPI) can readily protonate non-polar molecules and inert gases, including Ar, O2 , and N2 in thermal IMRs.	Nitrogen	131-133	ubiquitin specific peptidase like 1	Homo sapiens	14-36
28671633-0	2017	L1210 Cells Overexpressing ABCB1 Drug Transporters Are Resistant to Inhibitors of the N- and O-glycosylation of Proteins.	Nitrogen	86-87	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	27-32
28415009-4	2017	Compound 11a (with 4-methoxybenzoyl as N-substituent in the cap and 4-(aminomethyl) benzoyl as the linker group) exhibited selectivity against HDAC1 to some extent, and showed potent antiproliferative activity against several tumor cell lines.	Nitrogen	39-40	histone deacetylase 1	Homo sapiens	143-148
28614667-0	2017	N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity.	Nitrogen	0-1	calcitonin receptor	Homo sapiens	75-94
28614667-4	2017	Here, we define the role of CTR N-glycosylation in hormone binding using purified calcitonin and amylin receptor extracellular domain (ECD) glycoforms and fluorescence polarization/anisotropy and isothermal titration calorimetry peptide-binding assays.	Nitrogen	32-33	calcitonin receptor	Homo sapiens	28-31
28342358-1	2017	Highly efficient simultaneous removal of Pb(II) and p-nitrophenol (PNP) contamination from water was accomplished by nitrogen-functionalized magnetic ordered mesoporous carbon (N-Fe/OMC).	Nitrogen	117-125	submaxillary gland androgen regulated protein 3B	Homo sapiens	41-47
28685058-6	2017	Similarly, a higher T/N ratio, which is the ratio of CDC34 expression in HCCs to that in non-tumorous tissues, was significantly associated with favorable features, such as a lower indocyanin green retention rate after 15 min (ICG15R), reduced alpha-fetoprotein and smaller tumor size.	Nitrogen	22-23	alpha fetoprotein	Homo sapiens	244-261
28747925-6	2017	The optimized N rate (180 kg N ha-1) for the 90,000 plants ha-1 treatment achieved the highest yield with only 50% of the N fertilizer input commonly employed by local farmers" (360 kg N ha-1), which contributed to the increased N-uptake and N-transfer capacity.	Nitrogen	14-15	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	31-35
28747925-6	2017	The optimized N rate (180 kg N ha-1) for the 90,000 plants ha-1 treatment achieved the highest yield with only 50% of the N fertilizer input commonly employed by local farmers" (360 kg N ha-1), which contributed to the increased N-uptake and N-transfer capacity.	Nitrogen	14-15	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	59-63
28747925-6	2017	The optimized N rate (180 kg N ha-1) for the 90,000 plants ha-1 treatment achieved the highest yield with only 50% of the N fertilizer input commonly employed by local farmers" (360 kg N ha-1), which contributed to the increased N-uptake and N-transfer capacity.	Nitrogen	14-15	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	59-63
28747925-6	2017	The optimized N rate (180 kg N ha-1) for the 90,000 plants ha-1 treatment achieved the highest yield with only 50% of the N fertilizer input commonly employed by local farmers" (360 kg N ha-1), which contributed to the increased N-uptake and N-transfer capacity.	Nitrogen	29-30	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	31-35
28747925-6	2017	The optimized N rate (180 kg N ha-1) for the 90,000 plants ha-1 treatment achieved the highest yield with only 50% of the N fertilizer input commonly employed by local farmers" (360 kg N ha-1), which contributed to the increased N-uptake and N-transfer capacity.	Nitrogen	29-30	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	59-63
28747925-6	2017	The optimized N rate (180 kg N ha-1) for the 90,000 plants ha-1 treatment achieved the highest yield with only 50% of the N fertilizer input commonly employed by local farmers" (360 kg N ha-1), which contributed to the increased N-uptake and N-transfer capacity.	Nitrogen	29-30	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	59-63
28357470-3	2017	We show that (i) BMPR1A and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A.	Nitrogen	147-148	bone morphogenetic protein receptor type 1B	Homo sapiens	54-60
28560622-4	2017	The performance of MRAHD was better than that of MEC-based autotrophic denitrification for the wastewater treatment with low carbon nitrogen (COD/N) ratio.	Nitrogen	132-140	C-C motif chemokine ligand 28	Homo sapiens	49-52
30970932-6	2017	The results indicated that compared to oxygen plasma, nitrogen plasma treatment produced an anti-inflammatory effect on the collagen film by reducing the initial activation of monocytes and macrophages, which led to a lower production of pro-inflammatory cytokines IL-1beta and TNFalpha, and higher production of anti-inflammatory cytokine IL-10.	Nitrogen	54-62	interleukin 1 beta	Homo sapiens	265-273
28468779-4	2017	Here, we identified two novel types of NAM-competitive NAMPT inhibitors, only one of which contains a modifiable, aromatic nitrogen that could be a phosphoribosyl acceptor.	Nitrogen	123-131	SH3 and cysteine rich domain 3	Homo sapiens	39-42
29657554-6	2017	Further, the circulation under 3 mL min-1 elevated the nitrate removal by 33% and the final nitrate concentration fell below the maximum contaminant level of 10 mg L-1 nitrate-nitrogen (NO3-N).	Nitrogen	176-184	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
28545847-3	2017	As a result of agricultural activity and dense population, the shallow groundwater of this area is characterised by a high concentration of nitrogen compounds, primarily NO3-, with the concentration varying from 0.1mg/L to 206mg/L.	Nitrogen	140-148	NBL1, DAN family BMP antagonist	Homo sapiens	170-173
28545160-3	2017	Thus, in the present study, tumor-homing asparagine-glycine-arginine (NGR) peptide ligand was conjugated to DNA alkylating nitrogen mustard, chlorambucil (CLB).	Nitrogen	123-131	reticulon 4 receptor	Mus musculus	70-73
28482576-7	2017	The PEGylated triblock copolymer could chemically conjugate DOX onto PAH blocks via pH-responsive hydrazone bonds and simultaneously complex negatively charged Bcl-2 siRNA with cationic PDMAPMA blocks through electrostatic interactions at N/P ratios&gt;=32:1 to form multifunctional nanomicelleplexes.	Nitrogen	169-170	BCL2 apoptosis regulator	Homo sapiens	160-165
28554556-8	2017	Low urinary N-ter titin levels were detected in wild type rats (3.0 +- 0.6 ng/ml), while Dmdmdx rats exhibited a 556-fold increase (1652.5 +- 405.7 ng/ml, P = 0.002) (both at 5 months of age).	Nitrogen	12-13	titin	Rattus norvegicus	18-23
30970932-6	2017	The results indicated that compared to oxygen plasma, nitrogen plasma treatment produced an anti-inflammatory effect on the collagen film by reducing the initial activation of monocytes and macrophages, which led to a lower production of pro-inflammatory cytokines IL-1beta and TNFalpha, and higher production of anti-inflammatory cytokine IL-10.	Nitrogen	54-62	tumor necrosis factor	Homo sapiens	278-286
28604811-6	2017	Mean concentrations, over 56 sampling events, of total N (TN) and total P (TP) in surface runoff at the outlet pipe were 10.9+-6.34 and 1.3+-1.03 mg L-1, respectively.	Nitrogen	55-56	immunoglobulin kappa variable 1-16	Homo sapiens	149-152
28617514-2	2017	The stability of the complex was studied under air and N2 atmospheres and in CDCl3, DMSO, water and the cell culture medium, at room temperature and 40  C. The complex showed an enhanced antiproliferative activity (up to six-fold) when compared with its parent complex [RuCp(PPh3)2(HdmoPTA)]2+ against human lung, cervix, breast, and colon solid tumor cell lines.	Nitrogen	55-57	caveolin 1	Homo sapiens	275-279
28648037-22	2017	Conclusions: Activating SIRT1 on early stage of severe burn in rats can decrease levels of creatinine and urea nitrogen, thus improving the kidney function.	Nitrogen	111-119	sirtuin 1	Rattus norvegicus	24-29
28592651-8	2017	Based on these approaches, we were able to validate ARO1, PDC1, CPS1, ASI2, LYP1, and ALP1 allelic variants underlying nitrogen consumption differences between strains, providing evidence of many genes with small phenotypic effects.	Nitrogen	119-127	pentafunctional protein ARO1p	Saccharomyces cerevisiae S288C	52-56
29965365-11	2017	Finally, when the concentration of phosphate reached 100 mg L-1, the nitrogen removal efficiency of ANAMMOX was seriously inhibited.	Nitrogen	69-77	immunoglobulin kappa variable 1-16	Homo sapiens	60-63
28590904-2	2017	Using freeze fracture electron microscopy, we show here that the yeast NPC orthologs, Ncr1p and Npc2p, are essential for formation and expansion of raft-like domains in the vacuolar (lysosome) membrane, both in stationary phase and in acute nitrogen starvation.	Nitrogen	241-249	sphingolipid transporter	Saccharomyces cerevisiae S288C	86-91
28590904-2	2017	Using freeze fracture electron microscopy, we show here that the yeast NPC orthologs, Ncr1p and Npc2p, are essential for formation and expansion of raft-like domains in the vacuolar (lysosome) membrane, both in stationary phase and in acute nitrogen starvation.	Nitrogen	241-249	sterol transporter	Saccharomyces cerevisiae S288C	96-101
28592651-8	2017	Based on these approaches, we were able to validate ARO1, PDC1, CPS1, ASI2, LYP1, and ALP1 allelic variants underlying nitrogen consumption differences between strains, providing evidence of many genes with small phenotypic effects.	Nitrogen	119-127	indolepyruvate decarboxylase 1	Saccharomyces cerevisiae S288C	58-62
28592651-8	2017	Based on these approaches, we were able to validate ARO1, PDC1, CPS1, ASI2, LYP1, and ALP1 allelic variants underlying nitrogen consumption differences between strains, providing evidence of many genes with small phenotypic effects.	Nitrogen	119-127	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	64-68
27865927-4	2017	The EFSAM domain can undergo N-glycosylation at Asn131 and Asn171 sites; however, the precise role of EFSAM N-glycosylation in the Ca2+ sensing mechanism of STIM1 is unclear.	Nitrogen	29-30	stromal interaction molecule 1	Homo sapiens	157-162
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	7-9	Rho GTPase activating protein 45	Homo sapiens	133-142
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	7-9	Rho GTPase activating protein 45	Homo sapiens	161-170
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	7-9	Rho GTPase activating protein 45	Homo sapiens	161-170
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	7-9	Rho GTPase activating protein 45	Homo sapiens	161-170
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	40-48	Rho GTPase activating protein 45	Homo sapiens	133-142
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	40-48	Rho GTPase activating protein 45	Homo sapiens	161-170
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	40-48	Rho GTPase activating protein 45	Homo sapiens	161-170
28467048-4	2017	Adding N2O and N2 effluxes to catchment nitrogen output not only reduced the discrepancy between nitrogen inputs and outputs (9.9 kg ha-1 yr-1 and 6.5 or 6.3 kg ha-1 yr-1, respectively), but also between nitrogen outputs from two catchments with different topographies (6.5 kg ha-1 yr-1 for the catchment with a large wetland, 6.3 kg ha-1 yr-1 for the catchment with a very small wetland).	Nitrogen	40-48	Rho GTPase activating protein 45	Homo sapiens	161-170
28471669-1	2017	We not only modified the types and numbers of coordinated ligands in a metal agent to enhance its anticancer activity, but we also designed a metal prodrug based on the N-donor residues of the human serum albumin (HSA) IIA subdomain to improve its delivery efficiency and selectivity in vivo.	Nitrogen	169-170	albumin	Homo sapiens	199-222
28397166-4	2017	In the present study, N-glycosylation of IgG in RA patients and in healthy people was characterized through identification of the released glycans using multistage matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MSn), and quantitation by CE.	Nitrogen	22-23	moesin	Homo sapiens	252-255
28435067-0	2017	The mitogen-activated protein kinase kinase 9 (MKK9) modulates nitrogen acquisition and anthocyanin accumulation under nitrogen-limiting condition in Arabidopsis.	Nitrogen	63-71	MAP kinase kinase 9	Arabidopsis thaliana	47-51
28435067-0	2017	The mitogen-activated protein kinase kinase 9 (MKK9) modulates nitrogen acquisition and anthocyanin accumulation under nitrogen-limiting condition in Arabidopsis.	Nitrogen	119-127	MAP kinase kinase 9	Arabidopsis thaliana	47-51
28435067-6	2017	Taken together, our results suggest that MKK9 plays a role in plant adaptation to low N stress by modulating both anthocyanin accumulation and N status.	Nitrogen	86-87	MAP kinase kinase 9	Arabidopsis thaliana	41-45
27865927-4	2017	The EFSAM domain can undergo N-glycosylation at Asn131 and Asn171 sites; however, the precise role of EFSAM N-glycosylation in the Ca2+ sensing mechanism of STIM1 is unclear.	Nitrogen	108-109	stromal interaction molecule 1	Homo sapiens	157-162
28344130-4	2017	After mild renal ischemia-reperfusion (IR), AQP3 null mice had significantly greater blood urea nitrogen (57mg/dl) and creatinine (136muM) than wild-type mice (35mg/dl and 48muM, respectively), and showed renal morphological changes, including tubular dilatation, erythrocyte diapedesis and collecting duct incompletion.	Nitrogen	96-104	aquaporin 3	Mus musculus	44-48
27865927-5	2017	By establishing a site-specific chemical approach to covalently linking glucose to EFSAM and examining alpha-helicity, thermal stability, three dimensional atomic-resolution structure, Ca2+ binding affinity and oligomerization, we show that N-glycosylation of the EFSAM domain enhances the properties that promote STIM1 activation.	Nitrogen	241-242	stromal interaction molecule 1	Homo sapiens	314-319
27865927-7	2017	Congruently, Ca2+ influx via SOCE in HEK293 cells co-expressing Orai1 and STIM1 was diminished when N-glycosylation was blocked by introducing Asn131Gln and Asn171Gln mutations.	Nitrogen	100-101	stromal interaction molecule 1	Homo sapiens	74-79
27865927-8	2017	Collectively, our data suggests that N-glycosylation enhances the EFSAM destabilization-coupled oligomerization in response to ER Ca2+ depletion thereby augmenting the role of STIM1 as a robust ON/OFF regulator of SOCE.	Nitrogen	37-38	stromal interaction molecule 1	Homo sapiens	176-181
28257579-0	2017	An extracellular aminopeptidase encoded by the ywaD gene plays an important role in supplying nitrogen nutrition for the growth of Bacillus subtilis 168.	Nitrogen	94-102	putative fructose-lysine aminopeptidase	Bacillus subtilis subsp. subtilis str. 168	17-31
28515311-2	2017	Chk1, a mitotic checkpoint kinase and a client of Hsp90, was degraded relatively slowly in wild-type cells but was rapidly destroyed in naa10Delta cells by the Arg/N-end rule pathway, which recognized a C terminus-proximal degron of Chk1.	Nitrogen	164-165	serine/threonine protein kinase CHK1	Saccharomyces cerevisiae S288C	0-4
28197783-17	2017	Western blotting analysis on the expression of apoptosis regulatory proteins showed enhancement of proteocleavage-activated caspases 3, 8, and 9 and higher ratios of Bax/Bcl2 in the liquid nitrogen- and freezing nitrogen ethanol composite-treated samples.	Nitrogen	189-197	BCL2 associated X, apoptosis regulator	Homo sapiens	166-169
28197783-17	2017	Western blotting analysis on the expression of apoptosis regulatory proteins showed enhancement of proteocleavage-activated caspases 3, 8, and 9 and higher ratios of Bax/Bcl2 in the liquid nitrogen- and freezing nitrogen ethanol composite-treated samples.	Nitrogen	212-220	BCL2 associated X, apoptosis regulator	Homo sapiens	166-169
28197783-17	2017	Western blotting analysis on the expression of apoptosis regulatory proteins showed enhancement of proteocleavage-activated caspases 3, 8, and 9 and higher ratios of Bax/Bcl2 in the liquid nitrogen- and freezing nitrogen ethanol composite-treated samples.	Nitrogen	212-220	BCL2 apoptosis regulator	Homo sapiens	170-174
28502052-6	2017	In addition, the variation tendency of nitrogen functional gene abundances and their strong effects on NH4+-N, NO2--N, and NO3--N transformation were clearly observed.	Nitrogen	39-47	NBL1, DAN family BMP antagonist	Homo sapiens	123-126
28343064-7	2017	Furthermore, the expression of HvATG6 was upregulated by various abiotic stresses including dark, H2O2 treatment, nitrogen deficiency, high salinity, drought, low temperature and toxic aluminum.	Nitrogen	114-122	atg6	Hordeum vulgare	31-37
28515311-2	2017	Chk1, a mitotic checkpoint kinase and a client of Hsp90, was degraded relatively slowly in wild-type cells but was rapidly destroyed in naa10Delta cells by the Arg/N-end rule pathway, which recognized a C terminus-proximal degron of Chk1.	Nitrogen	164-165	Hsp90 family chaperone HSC82	Saccharomyces cerevisiae S288C	50-55
28013020-0	2017	Nitrogen-doped graphene quantum dots-labeled epitope imprinted polymer with double templates via the metal chelation for specific recognition of cytochrome c.	Nitrogen	0-8	cytochrome c, somatic	Homo sapiens	145-157
28542452-3	2017	Ape4 metalloproteases in other fungi, including Saccharomyces cerevisiae, are activated by nitrogen starvation, and they are required for autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway.	Nitrogen	91-99	aspartyl aminopeptidase	Saccharomyces cerevisiae S288C	0-4
28542452-7	2017	Similar to S. cerevisiae Ape4, the C. neoformans GFP-Ape4 fusion protein co-localized with intracytoplasmic vesicles during nitrogen depletion.	Nitrogen	124-132	aspartyl aminopeptidase	Saccharomyces cerevisiae S288C	53-57
28013020-1	2017	A novel fluorescent sensor nitrogen-doped graphene quantum dots (N-GQDs)/SiO2/molecular imprinting polymer(N-GQDs/SiO2/MIP)was fabricated by surface imprinting and epitope imprinting to recognize and detect the target protein cytochrome c (Cyt C) with fluorescence quenching.	Nitrogen	27-35	cytochrome c, somatic	Homo sapiens	226-238
28013020-1	2017	A novel fluorescent sensor nitrogen-doped graphene quantum dots (N-GQDs)/SiO2/molecular imprinting polymer(N-GQDs/SiO2/MIP)was fabricated by surface imprinting and epitope imprinting to recognize and detect the target protein cytochrome c (Cyt C) with fluorescence quenching.	Nitrogen	27-35	cytochrome c, somatic	Homo sapiens	240-245
28084055-3	2017	Dinuclear complex [3]I activates CS2 with formation of complex [5]I featuring the CS2 molecule bound through the carbon atom to the MIC nitrogen atom and one sulfur atom coordinating to the platinum center.	Nitrogen	136-144	chorionic somatomammotropin hormone 2	Homo sapiens	33-36
28228237-9	2017	Denitrification of NO3- to N2 occurred in anaerobic conditions, while at intermediate dissolved oxygen; N2O was the dominant reaction product.	Nitrogen	27-29	NBL1, DAN family BMP antagonist	Homo sapiens	19-22
28471403-5	2017	Flavivirus envelope proteins are N-glycosylated surface proteins, which interact with C-type lectins, dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) through their glycans.	Nitrogen	33-34	CD209 molecule	Homo sapiens	102-181
28471403-5	2017	Flavivirus envelope proteins are N-glycosylated surface proteins, which interact with C-type lectins, dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) through their glycans.	Nitrogen	33-34	CD209 molecule	Homo sapiens	183-190
28084055-3	2017	Dinuclear complex [3]I activates CS2 with formation of complex [5]I featuring the CS2 molecule bound through the carbon atom to the MIC nitrogen atom and one sulfur atom coordinating to the platinum center.	Nitrogen	136-144	chorionic somatomammotropin hormone 2	Homo sapiens	82-85
28658914-12	2017	Highly significant correlation was evident with N-Sn, EnR-EnL and AgR-AgL with p&lt;0.001.	Nitrogen	48-49	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	Homo sapiens	70-73
28187386-1	2017	A novel DEAMOX system was developed for nitrogen removal from domestic wastewater and nitrate (NO3--N) sewage in sequencing batch reactor (SBR).	Nitrogen	40-48	NBL1, DAN family BMP antagonist	Homo sapiens	95-98
28187386-4	2017	The total nitrogen (TN) removal efficiency was as high as 95.8% with influent NH4+-N of 63.58 mg L-1 and NO3--N of 69.24 mg L-1.	Nitrogen	10-18	L1 cell adhesion molecule	Homo sapiens	97-100
28012129-7	2017	Placental CD24 had an apparent molecular weight of 30-70 kDa consistent with its high degree of N- and O-linked glycosylation.	Nitrogen	96-97	CD24 molecule	Homo sapiens	10-14
28187386-4	2017	The total nitrogen (TN) removal efficiency was as high as 95.8% with influent NH4+-N of 63.58 mg L-1 and NO3--N of 69.24 mg L-1.	Nitrogen	10-18	NBL1, DAN family BMP antagonist	Homo sapiens	105-108
28187386-4	2017	The total nitrogen (TN) removal efficiency was as high as 95.8% with influent NH4+-N of 63.58 mg L-1 and NO3--N of 69.24 mg L-1.	Nitrogen	10-18	L1 cell adhesion molecule	Homo sapiens	124-127
28360125-5	2017	Increased Grb2-NOX4 interactions play a preventive role against cytoskeletal disassembly, in turn blocking the activity of nitrogen oxides and decreasing the expression of slingshot homolog 1 (SSH-1) protein, a potent inducer of cytoskeleton disassembly.	Nitrogen	123-131	growth factor receptor bound protein 2	Homo sapiens	10-14
28158920-6	2017	In particular, we explore how temporal variations in the external (biosphere and atmosphere) and internal (crust and mantle) nitrogen cycles could have regulated atmospheric pN2 .	Nitrogen	125-133	amyloid beta precursor protein	Homo sapiens	174-177
28158920-7	2017	We consider three potential scenarios for the evolution of the geobiological nitrogen cycle over Earth"s history: two in which atmospheric pN2 has changed unidirectionally (increased or decreased) over geologic time and one in which pN2 could have taken a dramatic deflection following the Great Oxidation Event.	Nitrogen	77-85	amyloid beta precursor protein	Homo sapiens	139-142
28158920-7	2017	We consider three potential scenarios for the evolution of the geobiological nitrogen cycle over Earth"s history: two in which atmospheric pN2 has changed unidirectionally (increased or decreased) over geologic time and one in which pN2 could have taken a dramatic deflection following the Great Oxidation Event.	Nitrogen	77-85	amyloid beta precursor protein	Homo sapiens	233-236
28201747-2	2017	Nitrate (NO3-) has a relevant role in plant-like organisms, first as a nitrogen source for growth and second as a signalling molecule.	Nitrogen	71-79	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
28393959-2	2017	The aryl-halogen bond hydroxylation and subsequent N,O-acetalization on CH2Cl2 are enabled under catalytic conditions which allows the generation of C(sp2)-O, C(sp3)-O and C(sp3)-N bonds to give the target products.	Nitrogen	51-52	Sp2 transcription factor	Homo sapiens	149-154
28426790-5	2017	Surprisingly, the additional deletion of the gene encoding endo-beta-N-acetylglucosaminidase (Engase), which is another de-N-glycosylating enzyme but leaves a single GlcNAc at glycosylated Asn residues, resulted in the partial rescue of the lethality of the Ngly1-deficient mice.	Nitrogen	69-70	endo-beta-N-acetylglucosaminidase	Mus musculus	94-100
28379231-2	2017	Two M8L12 cubic coordination cages, as desolvated crystalline powders, preferentially adsorb CO2 over N2 with ideal selectivity CO2/N2 constants of 49 and 30 at 298 K. A binding site for CO2 is suggested by crystallographic location of CS2 within the cage cavity at an electropositive hydrogen-bond donor site, potentially explaining the high CO2/N2 selectivity compared to other materials with this level of porosity.	Nitrogen	102-104	chorionic somatomammotropin hormone 2	Homo sapiens	236-239
28469611-0	2017	N2 Gas Flushing Limits the Rise of Antibiotic-Resistant Bacteria in Bovine Raw Milk during Cold Storage.	Nitrogen	0-2	Weaning weight-maternal milk	Bos taurus	79-83
28469611-10	2017	Our results imply that N2 gas flushing could strengthen cold storage of raw milk by tackling the bacterial spoilage potential while simultaneously hindering the increase of bacteria carrying antibiotic resistance/multi-resistance features.	Nitrogen	23-25	Weaning weight-maternal milk	Bos taurus	76-80
28323404-2	2017	The EPD conditions might also be of interest for the reduction of diazonium salts, which upon the release of N2 molecules and generation of radicals, can form covalent bonds with the sp2 hybridized carbon lattice atoms of rGO films.	Nitrogen	109-111	Sp2 transcription factor	Homo sapiens	183-186
28167607-0	2017	A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin alpha5 for Cell Migration.	Nitrogen	83-84	integrin subunit alpha 5	Homo sapiens	108-123
28381826-6	2017	In addition, TWIK2 contains two N-glycosylation sites (N79AS and N85AS) on its luminal side, and glycosylation is necessary for expression in lysosomes.	Nitrogen	32-33	potassium two pore domain channel subfamily K member 6	Homo sapiens	13-18
28164345-2	2017	GCMC simulations showed this impregnation can enhance CO2 /CH4 (or CO2 /N2 ) selectivity almost 30 times compared to the bare SPC due to the strong interaction of CO2 with the nPOMs@SPC structures.	Nitrogen	72-74	proline rich protein gene cluster	Homo sapiens	126-129
28164345-2	2017	GCMC simulations showed this impregnation can enhance CO2 /CH4 (or CO2 /N2 ) selectivity almost 30 times compared to the bare SPC due to the strong interaction of CO2 with the nPOMs@SPC structures.	Nitrogen	72-74	proline rich protein gene cluster	Homo sapiens	182-185
28164345-6	2017	As a result, the proposed nPOMs@SPC structures are promising candidates for CO2 /N2 and CO2 /CH4 separations.	Nitrogen	81-83	proline rich protein gene cluster	Homo sapiens	32-35
28460451-0	2017	Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation.	Nitrogen	105-106	fms related receptor tyrosine kinase 3	Homo sapiens	23-27
28460451-3	2017	In this study we show that abrogation of FLT3ITD glycoprotein maturation using low doses of the N-glycosylation inhibitor tunicamycin has anti-proliferative and pro-apoptotic effects on FLT3ITD-expressing human and murine cell lines.	Nitrogen	96-97	fms related receptor tyrosine kinase 3	Homo sapiens	41-45
28507700-9	2017	Gas permeation measurements on the MMM show a great improvement over the bare PIM-1 polymer for CO2/N2 separation based on the ideal selectivity.	Nitrogen	100-102	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	78-83
28296399-4	2017	The thermodynamic products of these reactions are low-spin, diamagnetic, Co(III) amido complexes that are either monomeric, when an external hydrogen atom source such as 1,4-cyclohexadiene is present, or dimeric products formed via C-C coupling of the azide aryl group and internal transfer of H  to the nitrogen.	Nitrogen	304-312	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	73-79
28333456-4	2017	In the BF2 complex of calixsmaragdyrin, the BF2 unit was bound to two pyrrolic nitrogens of the dipyrrin moiety of calixsmaragdyrin as deduced by detailed 1- and 2-dimensional NMR spectroscopy studies.	Nitrogen	79-88	forkhead box G1	Homo sapiens	7-10
28333456-4	2017	In the BF2 complex of calixsmaragdyrin, the BF2 unit was bound to two pyrrolic nitrogens of the dipyrrin moiety of calixsmaragdyrin as deduced by detailed 1- and 2-dimensional NMR spectroscopy studies.	Nitrogen	79-88	forkhead box G1	Homo sapiens	44-47
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	14-22	RGA-like 1	Arabidopsis thaliana	160-166
27487524-7	2017	The presence of biomass improves the simultaneous removal efficiency of nitrogen and phosphorus in the IPC BAF.	Nitrogen	72-80	BAF nuclear assembly factor 1	Homo sapiens	107-110
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	342-350	RGA-like 1	Arabidopsis thaliana	160-166
28339983-6	2017	These data demonstrate that ACR11 is an activator of GS2, giving it a mechanistic role in the nitrogen assimilation of A. thaliana.	Nitrogen	94-102	uridylyltransferase-like protein	Arabidopsis thaliana	28-33
28408900-6	2017	More recently, a novel activation mechanism was identified whereby mutated forms of calreticulin form complexes with TPO-R via its extracellular N-glycosylated domain.	Nitrogen	145-146	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	117-122
27401145-6	2017	However, recent data also support the role of TMEM165 in Golgi Mn2+ homeostasis then arguing for a putative role of Mn2+ transporter for TMEM165 essential to achieve the correct N-glycosylation process of proteins in the secretory pathway.	Nitrogen	178-179	transmembrane protein 165	Homo sapiens	137-144
28137749-1	2017	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein syntaxin-1 adopts a closed conformation when bound to Munc18-1, preventing binding to synaptobrevin-2 and SNAP-25 to form the ternary SNARE complex.	Nitrogen	12-13	vesicle associated membrane protein 2	Homo sapiens	176-191
28408900-6	2017	More recently, a novel activation mechanism was identified whereby mutated forms of calreticulin form complexes with TPO-R via its extracellular N-glycosylated domain.	Nitrogen	145-146	calreticulin	Homo sapiens	84-96
28118518-4	2017	The alteration of the D value by N-bound axial CN ligands, upon association with cyanometallates, was also assessed for heptacoordinated FeII as well as for related NiII and CoII derivatives.	Nitrogen	33-34	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	174-178
28100639-1	2017	Munc13-4 is a Ca2+-dependent SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor)- and phospholipid-binding protein that localizes to and primes secretory granules (SGs) for Ca2+-evoked secretion in various secretory cells.	Nitrogen	30-31	unc-13 homolog D	Rattus norvegicus	0-8
28189906-5	2017	SAR analysis showed that different substituents at C-3 and at the indole nitrogen led to different ABCB1 modulatory effects.	Nitrogen	73-81	ATP binding cassette subfamily B member 1	Homo sapiens	99-104
28281648-5	2017	Clustering analysis of HCPs showed that the concentration profiles of HCPs affecting mAb quality (Lgmn, Ctsd, Gbl1, and B4galt1) correlated with changes in mAb quality attributes such as aggregation, charge variants, and N-glycosylation during the cultures.	Nitrogen	221-222	legumain	Cricetulus griseus	98-102
28157264-1	2017	In this study, we proposed high-performance chemically regenerative redox fuel cells (CRRFCs) using NO3- /NO with a nitrogen-doped carbon-felt electrode and a chemical regeneration reaction of NO to NO3- via O2 .	Nitrogen	116-124	NBL1, DAN family BMP antagonist	Homo sapiens	100-103
28234479-2	2017	The reactions involve a regiospecific ring opening of aziridines with benzimidazoles to give benzoimidazolylethylamine derivatives that lead to dehydrogenative cross-coupling between C(sp2)-H and N-H bonds to produce dihydroimidazobenzimidazoles.	Nitrogen	196-197	Sp2 transcription factor	Homo sapiens	183-188
28194937-6	2017	Moreover, the similar result is also observed in liver-resident kupffer cells, which were isolated from the mice after treated with fluorescent-labeled native UOx and n(UOx).	Nitrogen	47-48	urate oxidase	Mus musculus	159-162
28194937-6	2017	Moreover, the similar result is also observed in liver-resident kupffer cells, which were isolated from the mice after treated with fluorescent-labeled native UOx and n(UOx).	Nitrogen	47-48	urate oxidase	Mus musculus	169-172
28194937-7	2017	Furthermore, n(UOx) exhibited significantly improved stability in vivo and a more than eightfold improvement in circulation time when compared with native UOx.	Nitrogen	13-14	urate oxidase	Mus musculus	15-18
28215986-0	2017	The beta4GalT1 affects the fibroblast-like synoviocytes invasion in rheumatoid arthritis by modifying N-linked glycosylation of CXCR3.	Nitrogen	102-103	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Mus musculus	4-14
28251984-2	2017	Herein, we report a solid nitrogen (SN2) cooling system as a valuable cryogenic feature, which is targeted for easy usability and stable operation under unreliable power source conditions, in conjunction with a magnesium diboride (MgB2) superconducting magnet.	Nitrogen	26-34	solute carrier family 38 member 5	Homo sapiens	36-39
28251984-2	2017	Herein, we report a solid nitrogen (SN2) cooling system as a valuable cryogenic feature, which is targeted for easy usability and stable operation under unreliable power source conditions, in conjunction with a magnesium diboride (MgB2) superconducting magnet.	Nitrogen	26-34	secretoglobin family 2A member 1	Homo sapiens	231-235
28186505-0	2017	N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death.	Nitrogen	0-1	TNF superfamily member 10	Homo sapiens	43-48
28089609-10	2017	It was previously demonstrated that N-glycosylation improved IFN-alpha pharmacokinetic properties.	Nitrogen	36-37	interferon alpha 1	Homo sapiens	61-70
28093671-7	2017	Among the three types of purple parent rock, J3p exhibited the best inhibitory effect on the release of nitrogen in sediments, and the inhibition efficiency of TN, NH4-N, and NO3-N was 59.7, 77.6, and 45.1%, respectively.	Nitrogen	104-112	immunoglobulin lambda joining 3	Homo sapiens	45-48
27627884-4	2017	These clusters are located in intrinsically disordered regions and via short linear motifs influence interactions with TGM2 partners directly, or through post-translation modification (phosphorylation and N-glycosylation sites).	Nitrogen	205-206	transglutaminase 2	Homo sapiens	119-123
28107996-7	2017	Gamma irradiation and nitrogen purging proved of some benefit for mitigating TNT degradation, with lower storage temperatures ultimately proving the most effective method of mitigating degradation.	Nitrogen	22-30	chromosome 16 open reading frame 82	Homo sapiens	77-80
30148555-2	2017	With yellow-green YGG phosphor and nitrogen red phosphors mixing with silica gel, the remote phosphor is made and then encapsulated as the LED lamps.	Nitrogen	35-43	small integral membrane protein 10 like 2A	Homo sapiens	139-142
27893932-1	2017	Subsurface brines with high nitrate (NO3- ) concentration are common in desert environments as atmospheric nitrogen is concentrated by the evaporation of precipitation and little nitrogen uptake.	Nitrogen	107-115	NBL1, DAN family BMP antagonist	Homo sapiens	37-40
27893932-3	2017	A NO3- solute mass balance analysis of the sabkha aquifer system suggests that more than 90% of the nitrogen is from local atmospheric deposition and the remainder from ascending brine.	Nitrogen	100-108	NBL1, DAN family BMP antagonist	Homo sapiens	2-5
27893932-7	2017	In this environment, NO3- is partially reduced to nitrogen gas (N2 ), thus enriching the remaining NO3- in heavy isotopes.	Nitrogen	50-58	NBL1, DAN family BMP antagonist	Homo sapiens	21-24
27893932-7	2017	In this environment, NO3- is partially reduced to nitrogen gas (N2 ), thus enriching the remaining NO3- in heavy isotopes.	Nitrogen	50-58	NBL1, DAN family BMP antagonist	Homo sapiens	99-102
27893932-7	2017	In this environment, NO3- is partially reduced to nitrogen gas (N2 ), thus enriching the remaining NO3- in heavy isotopes.	Nitrogen	64-66	NBL1, DAN family BMP antagonist	Homo sapiens	21-24
27893932-7	2017	In this environment, NO3- is partially reduced to nitrogen gas (N2 ), thus enriching the remaining NO3- in heavy isotopes.	Nitrogen	64-66	NBL1, DAN family BMP antagonist	Homo sapiens	99-102
27893932-8	2017	The isotopically fractionated NO3- and nitrogen gas return to the near-surface oxidizing environment on the upward displacement leg of the free-convection cycle, where the nitrogen gas is released to the atmosphere and new NO3- is added to the system from atmospheric deposition.	Nitrogen	39-47	NBL1, DAN family BMP antagonist	Homo sapiens	223-226
27893932-8	2017	The isotopically fractionated NO3- and nitrogen gas return to the near-surface oxidizing environment on the upward displacement leg of the free-convection cycle, where the nitrogen gas is released to the atmosphere and new NO3- is added to the system from atmospheric deposition.	Nitrogen	172-180	NBL1, DAN family BMP antagonist	Homo sapiens	30-33
28117266-3	2017	AIM: To investigate whether ESR1 polymorphisms (TA)n-rs3138774, PvuII-rs2234693, and XbaI-rs9340799 and their haplotypes are associated with gender dysphoria in adults.	Nitrogen	9-10	estrogen receptor 1	Homo sapiens	28-32
28177601-5	2017	Structural characterization of the Ni site using XAS showed a coordination change from six-coordinate in wild-type HypA (WT-HypA) to five-coordinate pyramidal in L2*-HypA, which was accompanied by the loss of two N/O donor protein ligands and the addition of an exogenous bromide ligand from the buffer.	Nitrogen	35-36	pre-mRNA processing factor 40 homolog A	Homo sapiens	115-119
28249157-6	2017	This suggests that the hitherto obscure role of Glo2 in mitochondria is to act upstream of Sirt3 in minimizing protein N-acetylation, thus limiting protein dysfunction when AcCoA accumulates.	Nitrogen	119-120	sirtuin 3	Homo sapiens	91-96
28177601-5	2017	Structural characterization of the Ni site using XAS showed a coordination change from six-coordinate in wild-type HypA (WT-HypA) to five-coordinate pyramidal in L2*-HypA, which was accompanied by the loss of two N/O donor protein ligands and the addition of an exogenous bromide ligand from the buffer.	Nitrogen	35-36	pre-mRNA processing factor 40 homolog A	Homo sapiens	124-128
28177601-5	2017	Structural characterization of the Ni site using XAS showed a coordination change from six-coordinate in wild-type HypA (WT-HypA) to five-coordinate pyramidal in L2*-HypA, which was accompanied by the loss of two N/O donor protein ligands and the addition of an exogenous bromide ligand from the buffer.	Nitrogen	35-36	pre-mRNA processing factor 40 homolog A	Homo sapiens	124-128
28952497-5	2017	In this paper, we report on synergistic effects of inorganic cerium oxide (IV) nanoparticles conjugated with the antioxidative enzymes superoxide dismutase and catalase on scavenging oxygen and nitrogen radicals.	Nitrogen	194-202	catalase	Homo sapiens	160-168
28220788-3	2017	However, computations predict that the charge distribution of NO3- is anisotropic and minimal on nitrogen.	Nitrogen	97-105	NBL1, DAN family BMP antagonist	Homo sapiens	62-65
28223691-2	2017	This study investigated the effect of N-linked glycosylation on the binding of Herceptin to HER2 protein in breast cancer and on the sensitivity of cancer cells to the chemotherapeutic agent doxorubicin (DXR) and growth factors (EGF and IGF-1).	Nitrogen	38-39	erb-b2 receptor tyrosine kinase 2	Homo sapiens	92-96
28087398-3	2017	P9-1 and P6 are the major and minor components of the viroplasms respectively, whereas P9-2 is an N-glycosylated membrane protein of unknown function.	Nitrogen	98-99	advillin	Homo sapiens	87-91
27249226-4	2017	The results showed that the concentration of ammonia nitrogen in wastewater could be reduced from 120.2 to 6.0 mg L-1, and manganese could be simultaneously removed from 302.4 to 1.5 mg L-1 at initial pH of 8.0, the mole ratios of nitrite and ammonia nitrogen of 1.5:1, and voltage of 20 V direct current electrolysis for 4.0 h. XRD analysis showed that manganese dioxide was deposited on the anode, and manganese was mainly removed in the form of manganese hydroxide precipitation in the cathode chamber.	Nitrogen	53-61	immunoglobulin kappa variable 1-16	Homo sapiens	114-117
29964510-8	2017	The inflow nutrients loads increased significantly in the summer of the normal year, as a result, total nitrogen increased from 1.00 mg L-1 to 2.06 mg L-1, nitrate increased from 0.19 mg L-1 to 1.28 mg L-1, and total phosphorus increased from 0.023 mg L-1 to 0.088 mg L-1 in the lacustrine zone of the reservoir.	Nitrogen	104-112	immunoglobulin kappa variable 1-16	Homo sapiens	136-139
29964510-8	2017	The inflow nutrients loads increased significantly in the summer of the normal year, as a result, total nitrogen increased from 1.00 mg L-1 to 2.06 mg L-1, nitrate increased from 0.19 mg L-1 to 1.28 mg L-1, and total phosphorus increased from 0.023 mg L-1 to 0.088 mg L-1 in the lacustrine zone of the reservoir.	Nitrogen	104-112	immunoglobulin kappa variable 1-16	Homo sapiens	151-154
29964510-8	2017	The inflow nutrients loads increased significantly in the summer of the normal year, as a result, total nitrogen increased from 1.00 mg L-1 to 2.06 mg L-1, nitrate increased from 0.19 mg L-1 to 1.28 mg L-1, and total phosphorus increased from 0.023 mg L-1 to 0.088 mg L-1 in the lacustrine zone of the reservoir.	Nitrogen	104-112	immunoglobulin kappa variable 1-16	Homo sapiens	151-154
29964510-8	2017	The inflow nutrients loads increased significantly in the summer of the normal year, as a result, total nitrogen increased from 1.00 mg L-1 to 2.06 mg L-1, nitrate increased from 0.19 mg L-1 to 1.28 mg L-1, and total phosphorus increased from 0.023 mg L-1 to 0.088 mg L-1 in the lacustrine zone of the reservoir.	Nitrogen	104-112	immunoglobulin kappa variable 1-16	Homo sapiens	151-154
29964510-8	2017	The inflow nutrients loads increased significantly in the summer of the normal year, as a result, total nitrogen increased from 1.00 mg L-1 to 2.06 mg L-1, nitrate increased from 0.19 mg L-1 to 1.28 mg L-1, and total phosphorus increased from 0.023 mg L-1 to 0.088 mg L-1 in the lacustrine zone of the reservoir.	Nitrogen	104-112	immunoglobulin kappa variable 1-16	Homo sapiens	151-154
29964510-8	2017	The inflow nutrients loads increased significantly in the summer of the normal year, as a result, total nitrogen increased from 1.00 mg L-1 to 2.06 mg L-1, nitrate increased from 0.19 mg L-1 to 1.28 mg L-1, and total phosphorus increased from 0.023 mg L-1 to 0.088 mg L-1 in the lacustrine zone of the reservoir.	Nitrogen	104-112	immunoglobulin kappa variable 1-16	Homo sapiens	151-154
28275390-3	2017	Reactive oxygen species (ROS) and nitrogen species (RNS) activate transcriptional factors (NF-KB, STAT-3) and bring about cellular proliferation, genomic instability, angiogenesis, resistance to apoptosis, invasion, and metastasis.	Nitrogen	34-42	signal transducer and activator of transcription 3	Homo sapiens	98-104
28182666-5	2017	In addition, the amount of cyclic adenosine monophosphate (cAMP) formed by the catalytic enzyme adenylate cyclase, which requires cellular calmodulin for its activity, was significantly increased in leaves treated with CO2 or N2 plasma, also indicating the introduction of sGFP-fused adenylate cyclase into the cells.	Nitrogen	226-228	calmodulin 1	Homo sapiens	139-149
28150819-0	2017	Legacy of contaminant N sources to the NO3- signature in rivers: a combined isotopic (delta15N-NO3-, delta18O-NO3-, delta11B) and microbiological investigation.	Nitrogen	22-23	NBL1, DAN family BMP antagonist	Homo sapiens	39-42
27748203-5	2017	N-NS treatment prevented (P &lt; 0 05) ROS and TBARS increase, and increased NPSH levels, and ameliorate CAT and SOD activities on liver of infected mice.	Nitrogen	0-1	catalase	Mus musculus	105-108
27735062-6	2017	Fe starvation triggered Moco biosynthesis and affected the molybdo-enzymes, with its main impact on nitrate reductase and xanthine dehydrogenase, both being involved in nitrogen assimilation and mobilization, and on the mitochondrial amidoxime reducing component.	Nitrogen	169-177	nitrate reductase [NADH]-like	Cucumis sativus	100-117
27746357-2	2017	The experimental results indicated that not only the fibrillation of HEWL at high temperature (65 C) and low pH (pH=2.0) could be inhibited effectively by N-GQDs, but the inhibition of HEWL by N-GQDs followed a dose-dependent manner.	Nitrogen	155-156	sperm adhesion molecule 1	Homo sapiens	113-119
27748203-5	2017	N-NS treatment prevented (P &lt; 0 05) ROS and TBARS increase, and increased NPSH levels, and ameliorate CAT and SOD activities on liver of infected mice.	Nitrogen	2-4	catalase	Mus musculus	105-108
28966476-0	2017	A persistent-mode 0.5 T solid-nitrogen-cooled MgB2 magnet for MRI.	Nitrogen	30-38	secretoglobin family 2A member 1	Homo sapiens	46-50
27887827-8	2017	Irrigation with NO3 concentrated groundwater induces a "hidden" input of nitrogen to the crop which can reach 200kgN/ha/yr in hotspot areas, enhancing groundwater contamination.	Nitrogen	73-81	NBL1, DAN family BMP antagonist	Homo sapiens	16-19
28134235-1	2017	BACKGROUND We designed this study to investigate the influence of different ratios of n-6/n-3 polyunsaturated fatty acid in the diet of reflux esophagitis (RE) rats" and the effect on the PI3K/Akt pathway.	Nitrogen	19-20	AKT serine/threonine kinase 1	Rattus norvegicus	193-196
27997792-0	2017	Tethering an N-Glycosylation Sequon-Containing Peptide Creates a Catalytically Competent Oligosaccharyltransferase Complex.	Nitrogen	13-14	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	89-114
28134235-6	2017	CONCLUSIONS The inhibition of n-3 PUFAs in the development of esophageal inflammation in rats with RE was attributed to the function of PI3K/Akt-NF-kappaB signaling pathway.	Nitrogen	17-18	AKT serine/threonine kinase 1	Rattus norvegicus	141-144
28125599-0	2017	N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.	Nitrogen	0-1	solute carrier family 10 member 1	Homo sapiens	68-72
28125599-3	2017	NTCP contains two N-linked glycosylation sites and asparagine amino acid residues N5 and N11 were mutated to a glutamine to generate NTCP with a single glycan (NTCP-N5Q or NTCP- N11Q) or no glycans (NTCP- N5,11Q).	Nitrogen	0-1	solute carrier family 10 member 1	Homo sapiens	133-137
28125599-3	2017	NTCP contains two N-linked glycosylation sites and asparagine amino acid residues N5 and N11 were mutated to a glutamine to generate NTCP with a single glycan (NTCP-N5Q or NTCP- N11Q) or no glycans (NTCP- N5,11Q).	Nitrogen	0-1	solute carrier family 10 member 1	Homo sapiens	133-137
28125599-3	2017	NTCP contains two N-linked glycosylation sites and asparagine amino acid residues N5 and N11 were mutated to a glutamine to generate NTCP with a single glycan (NTCP-N5Q or NTCP- N11Q) or no glycans (NTCP- N5,11Q).	Nitrogen	0-1	solute carrier family 10 member 1	Homo sapiens	133-137
28125599-3	2017	NTCP contains two N-linked glycosylation sites and asparagine amino acid residues N5 and N11 were mutated to a glutamine to generate NTCP with a single glycan (NTCP-N5Q or NTCP- N11Q) or no glycans (NTCP- N5,11Q).	Nitrogen	0-1	solute carrier family 10 member 1	Homo sapiens	133-137
28149202-10	2016	In particular, the altered abundance of kynureninase (KYNU) and HAL (histidine ammonia-lyase) involved in protein metabolic function, integrated with the changes of serum levels of blood urea nitrogen (BUN) and glucose (GLU), suggest that overgrazing triggers a shift in energy resources from carbohydrates to proteins, causing poorer nitrogen utilization efficiency.	Nitrogen	192-200	histidine ammonia-lyase	Ovis aries	64-67
27908775-2	2017	General amino acid permease Gap1p is response of aromatic amino acids transportation, and GATA transcription factors Gln3p and Gat1p regulate the transcription of permease gene and catabolic enzyme genes for nitrogen sources and aromatic amino acids utilization.	Nitrogen	208-216	amino acid permease GAP1	Saccharomyces cerevisiae S288C	28-33
28085964-4	2017	The kinetic parametors kcat, Vmax and kcat/Km in the OPH reaction were remarkably increased in the buffers (pH 8.0, 25 C) containing aminoalcohols with C2 between nitrogen (N) and oxygen (O) in their structures, including triethanolamine (TEA), diethanolamine, monoethanolamine, 1-amino-2-propanol, 2-amino-2-methyl-1-propanol, and triisopropanolamine.	Nitrogen	163-171	acylaminoacyl-peptide hydrolase	Homo sapiens	53-56
27936662-5	2017	The strong electron-phonon coupling of the vanadia particles has been proposed to create the O - radicals (V5+ = O2-+ heat   V4+-O -) for the n &gt; 25 clusters with Delta = -2, -1, 0, and 2.	Nitrogen	8-9	delta like non-canonical Notch ligand 1	Homo sapiens	166-190
28149202-10	2016	In particular, the altered abundance of kynureninase (KYNU) and HAL (histidine ammonia-lyase) involved in protein metabolic function, integrated with the changes of serum levels of blood urea nitrogen (BUN) and glucose (GLU), suggest that overgrazing triggers a shift in energy resources from carbohydrates to proteins, causing poorer nitrogen utilization efficiency.	Nitrogen	192-200	histidine ammonia-lyase	Ovis aries	69-92
28149202-10	2016	In particular, the altered abundance of kynureninase (KYNU) and HAL (histidine ammonia-lyase) involved in protein metabolic function, integrated with the changes of serum levels of blood urea nitrogen (BUN) and glucose (GLU), suggest that overgrazing triggers a shift in energy resources from carbohydrates to proteins, causing poorer nitrogen utilization efficiency.	Nitrogen	335-343	histidine ammonia-lyase	Ovis aries	64-67
28742884-2	2017	However, the relationship between alterations in N-glycosylation process and loss of E-cadherin adhesion in cancer remains unclear.	Nitrogen	49-50	cadherin 1	Homo sapiens	85-95
29151838-1	2017	Anthropogenic nitrogen (N) emissions to the atmosphere have increased significantly the deposition of nitrate (NO3-) and ammonium (NH4+) to the surface waters of the open ocean, with potential impacts on marine productivity and the global carbon cycle.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	111-114
28676924-9	2017	Furthermore, this chapter discusses the post-translational modification of the P2X7 receptor by N-linked glycosylation, adenosine 5"-diphosphate ribosylation and palmitoylation.	Nitrogen	96-97	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	79-92
27822701-0	2017	AglH, a thermophilic UDP-N-acetylglucosamine-1-phosphate:dolichyl phosphate GlcNAc-1-phosphotransferase initiating protein N-glycosylation pathway in Sulfolobus acidocaldarius, is capable of complementing the eukaryal Alg7.	Nitrogen	25-26	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	218-222
27822701-2	2017	AglH successfully replaced the endogenous GlcNAc-1-phosphotransferase activity of Alg7 in a conditional lethal Saccharomyces cerevisiae strain, in which the first step of the eukaryal protein N-glycosylation process was repressed.	Nitrogen	45-46	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	82-86
27923447-7	2017	Moreover, fat-1 transgenic mice treated with N-IgY showed significant downregulation of genes involved in cholesterol-induced hepatic stellate cell activation (Tgfb1, Tlr4, Col1a1, Col1a2, and Timp2).	Nitrogen	45-46	toll-like receptor 4	Mus musculus	167-171
27834568-6	2017	Removal of the Fab N-glycosylation site by single amino acid substitution, or removal of N-linked glycans by enzymatic digestion, drastically reduced the antibody"s ability to inhibit latency-associated peptide (LAP) and alphavbeta8 association, and TGF-beta activation in an alphavbeta8-mediated TGF-beta signaling reporter assay.	Nitrogen	19-20	transforming growth factor beta 1	Homo sapiens	184-210
27956494-4	2017	We previously showed that Sch9p impact on longevity depends on the nitrogen/carbon ratio.	Nitrogen	67-75	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	26-31
27956494-5	2017	When nitrogen is limiting, SCH9 deletion shortens chronological life span, which is the case under winemaking conditions.	Nitrogen	5-13	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	27-31
29188863-13	2017	CONCLUSIONS: The role of n-3 PUFAs on the relationship between homocysteine and cerebral Abeta warrants further investigation.	Nitrogen	25-26	amyloid beta precursor protein	Homo sapiens	89-94
27923447-7	2017	Moreover, fat-1 transgenic mice treated with N-IgY showed significant downregulation of genes involved in cholesterol-induced hepatic stellate cell activation (Tgfb1, Tlr4, Col1a1, Col1a2, and Timp2).	Nitrogen	45-46	collagen, type I, alpha 1	Mus musculus	173-179
28178702-9	2017	We also demonstrated that the altered pattern of N-linked glycosylation induces an over-expression of binding immunoglobulin protein and calreticulin, suggesting ER stress.	Nitrogen	49-50	calreticulin	Homo sapiens	137-149
28935112-2	2017	The central enzyme in N-linked glycosylation is the oligosaccharyltransferase (OST), which catalyzes the covalent attachment of preassembled glycans to specific asparagine residues in target proteins.	Nitrogen	22-23	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	52-77
28935112-2	2017	The central enzyme in N-linked glycosylation is the oligosaccharyltransferase (OST), which catalyzes the covalent attachment of preassembled glycans to specific asparagine residues in target proteins.	Nitrogen	22-23	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	79-82
27773243-3	2017	The X-ray structure revealed that the Pb(II) atom is coordinated by one oxygen and three nitrogen atoms from two qcnh ligands and five oxygen atoms from three nitrate ligands in an 8+1 fashion with a PbN3O6 donor set.	Nitrogen	89-97	submaxillary gland androgen regulated protein 3B	Homo sapiens	38-44
31275011-5	2017	We previously showed that the plant specific ubiquitin ligase ATL31 regulates the carbon/nitrogen-nutrient response and pathogen resistance in Arabidopsis, and we identified and characterized the basic biochemical function of an ATL31 homologue in tomato plants (Solanum lycopersicum L.).	Nitrogen	89-97	ubiquitin-40S ribosomal protein S27a	Solanum lycopersicum	45-54
31275021-6	2017	The expression levels of NITRATE TRANSPORTER 2.1, ASPARAGINE SYNTHETASE and NITRATE REDUCTASE 1 were significantly higher in roots of 35S:GATA4-SRDX plants than in wild type under nitrogen-sufficient conditions.	Nitrogen	180-188	nitrate transporter 2:1	Arabidopsis thaliana	25-48
27697340-5	2017	The N-NH4+/N-NO3- ratio, both in precipitation and wet deposition, has been increasing steadily, reflecting the changes in reduced and oxidized forms of nitrogen emissions.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	13-16
27933961-2	2016	Crystal structures of prototypical members bound to the ATP-binding site of TNNI3K reveal two anchoring hydrogen bond contacts: (1) from the hinge region amide N-H to the pyrimidine nitrogen and (2) from the sulfonamide N-H to the gatekeeper threonine.	Nitrogen	182-190	TNNI3 interacting kinase	Homo sapiens	76-82
27984871-1	2016	A nitrate ion (NO3-) with its trigonal planar geometry and charges distributed among nitrogen and oxygen atoms can couple to the extensive hydrogen bond network of water to give rise to unique dynamical characteristics.	Nitrogen	85-93	NBL1, DAN family BMP antagonist	Homo sapiens	15-18
27605461-3	2016	METHODS: The ammonium nitrate (NH4 NO3 ) decomposition technique provides a strategy to scale the 15 N site-specific (SP   delta15 Nalpha - delta15 Nbeta ) and bulk (delta15 Nbulk  = (delta15 Nalpha  + delta15 Nbeta )/2) isotopic composition of N2 O against the international standard for the 15 N/14 N isotope ratio (AIR-N2 ).	Nitrogen	245-247	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
27605461-5	2016	RESULTS: The validity of the NH4 NO3 decomposition technique to link NH4+ and NO3- moiety-specific delta15 N analysis by IRMS to the site-specific nitrogen isotopic composition of N2 O was confirmed.	Nitrogen	147-155	NBL1, DAN family BMP antagonist	Homo sapiens	33-36
27960294-4	2016	Results showed that compared with the control group, low-protein diets with the BCAA ratio ranging from 1:0.75:0.75 to 1:0.25:0.25 elevated muscle free amino acid (AA) concentrations and AA transporter expression, significantly activated the mammalian target of rapamycin complex 1 pathway, and decreased serum urea nitrogen content and the mRNA expression of genes related to muscle protein degradation (P &lt; 0.05).	Nitrogen	316-324	AT-rich interaction domain 4B	Homo sapiens	80-84
27908452-9	2017	This study concludes that NO3- formation during ozonation of DON is induced by an oxygen-transfer to nitrogen forming hydroxylamine and oxime, while NH4+ formation is induced by electron-transfer reactions involving C-centered radicals and imine intermediates.	Nitrogen	101-109	NBL1, DAN family BMP antagonist	Homo sapiens	26-29
28030611-14	2016	PDGF also modulated the process of N-glycosylation of the PDGFRbeta in a proteasome-dependent manner.	Nitrogen	35-36	platelet derived growth factor receptor beta	Homo sapiens	58-67
27476061-4	2016	The coordination interaction between nitrogen functional groups of the CEA aptamer and PdNPs brought UCPs and PdNPs in close proximity, which resulted in the fluorescence quenching of UCPs to an extent of 85%.	Nitrogen	37-45	CEA cell adhesion molecule 3	Homo sapiens	71-74
27693235-4	2016	The dDad1 protein, an orthologue of mammalian Dad1, was found to be crucial for protein N-glycosylation in developing tissues.	Nitrogen	88-89	Daughters against dpp	Drosophila melanogaster	4-9
27760464-6	2016	165 site-specific N-glycopeptides representative of all N-glycosylation sites were identified from AGP 1 and AGP 2 isoforms.	Nitrogen	18-19	orosomucoid 1	Homo sapiens	99-104
27380303-3	2016	DFT calculations suggested that superior HOMO distributions spread over the nitrogen-donor (as well as somehow oxygen- donor in L2) groups of L1 and L2 macrocycles were the key factor for the observed Kb value enhancement.	Nitrogen	76-84	L1 cell adhesion molecule	Homo sapiens	142-151
28330312-12	2016	L-Asparaginase production by C7 was higher with glucose as carbon source and asparagine as nitrogen source.	Nitrogen	91-99	asparaginase and isoaspartyl peptidase 1	Homo sapiens	0-14
27565712-2	2016	Here, we present evidence that the membrane-proximal N-glycosylation on integrin beta1 could positively regulate cell migration by promoting beta1 activation.	Nitrogen	53-54	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	81-86
27565712-3	2016	The S4-6 beta1 mutant contains only 3 N-glycosylation sites, which are essential for alpha5 and beta1 heterodimer formation, and despite only a small difference in expression levels of alpha5beta1 between wild-type and S4-6 mutant, cell spreading and migration of the S4-6 mutant was significantly decreased compared with that of control.	Nitrogen	38-39	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	9-14
27565712-6	2016	Further study on the regulatory mechanisms suggested that membrane-proximal N-glycosylation is critical for intermolecular interactions between integrin beta1 and other cell membrane proteins, such as syndecan-4 and epidermal growth factor receptor.	Nitrogen	76-77	epidermal growth factor receptor	Homo sapiens	216-248
27565712-8	2016	These data suggest a novel regulatory mechanism wherein N-glycosylation near the cell membrane on beta1 may serve as a platform that facilitates its complex formation on the cell membrane, thereby affecting integrin-mediated functions.-Hou, S., Hang, Q., Isaji, T., Lu, J., Fukuda, T., Gu, J.	Nitrogen	56-57	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	98-103
27959879-6	2016	The ratios of nitrogen and oxygen stable isotopes indicated that NO3- contamination of groundwater at Oyu Tolgoi and Tavan Tolgoi was caused by livestock waste.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	65-68
27127844-5	2016	Here we ask if human a4 (ATP6V0A4) is N-glycosylated at the predicted site, Asn489.	Nitrogen	38-39	ATPase H+ transporting V0 subunit a4	Homo sapiens	25-33
27792900-2	2016	Among animals, loss of the Moco-containing enzyme (Mo-enzyme) sulphite oxidase is lethal, while for plants the loss of nitrate reductase prohibits nitrogen assimilation.	Nitrogen	147-155	nitrate reductase 1	Arabidopsis thaliana	119-136
27694802-6	2016	These results identify OST inhibition as a potential therapeutic approach for treating receptor-tyrosine-kinase-dependent tumors and provides a chemical probe for reversibly regulating N-linked glycosylation in mammalian cells.	Nitrogen	185-186	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	23-26
27994690-1	2016	68Ga-Prostate specific membrane antigen- N,N"-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid- positron emission tomography/computed tomography or 68 Ga- HBED-CC-PSMA PET/CT, popularly known as PSMA PET/CT, is able to detect a small volume of recurrent prostate carcinoma (PC) when there is a prostate specific antigen (PSA) rise on follow-up after prostatectomy or other definitive treatment for PC.	Nitrogen	41-42	folate hydrolase 1	Homo sapiens	186-190
27994690-1	2016	68Ga-Prostate specific membrane antigen- N,N"-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid- positron emission tomography/computed tomography or 68 Ga- HBED-CC-PSMA PET/CT, popularly known as PSMA PET/CT, is able to detect a small volume of recurrent prostate carcinoma (PC) when there is a prostate specific antigen (PSA) rise on follow-up after prostatectomy or other definitive treatment for PC.	Nitrogen	41-42	folate hydrolase 1	Homo sapiens	218-222
27095603-2	2016	Transferrin is an 80 kDa glycoprotein and the glycoform at two N-glycosylation sites is comprised of a di-sialylated biantennary oligosaccharide as the major form and minor species with fucosylated or triantennary structures.	Nitrogen	63-64	transferrin	Homo sapiens	0-11
27883045-9	2016	Thus, AMCase can function as a protease-resistant major glycosidase under the conditions of stomach and intestine and degrade chitin substrates to produce (GlcNAc)2, a source of carbon, nitrogen and energy.	Nitrogen	186-194	chitinase, acidic 1	Mus musculus	6-12
27639963-10	2016	Furthermore, the results suggest that after N addition Na+, nitrite, nitrate, ammonium contents, nitrogen metabolic enzymes, proline content, and activity of P5CS are favourably regulated, which might be associated with mitigation of NaCl stress and effect was more pronounced with supra-optimum level of N (N150).	Nitrogen	44-45	delta-1-pyrroline-5-carboxylate synthase	Solanum lycopersicum	158-162
27546343-11	2016	The current exercise suggests that the DailyDayCent may need improvement, particularly the sub-module responsible for N transformations, for better simulating soil mineral N, especially soil NO3- concentration, and N2O flux on a daily basis.	Nitrogen	118-119	NBL1, DAN family BMP antagonist	Homo sapiens	191-194
27697682-10	2016	At lower aeration states, nitrogen cycling patterns, supported by molecular investigations targeting AOBs and NOBs, indicate that NO2 and NO3 sustained feast-famine PHA synthesis.	Nitrogen	26-34	NBL1, DAN family BMP antagonist	Homo sapiens	138-141
29964663-4	2016	The main form of inorganic nitrogen (DIN) in dry deposition was NO3- deposition (0.71 kg hm-2), with NH4+ deposition (0.37 kg hm-2) being lower compared to NO3- deposition.	Nitrogen	27-35	NBL1, DAN family BMP antagonist	Homo sapiens	64-67
27737912-4	2016	Here, we show that in a distantly related fungal organism, the fission yeast Schizosaccharomyces pombe, autophagy of ER and mitochondria is induced by nitrogen starvation and is promoted by three Atg20- and Atg24-family proteins - Atg20, Atg24 and SPBC1711.11 (named here as Atg24b).	Nitrogen	151-159	Snx4p	Saccharomyces cerevisiae S288C	238-243
27786475-3	2016	293 K04 produces the N-methylated peptides endolide A (1) and endolide B (2), showing affinity for the vasopressin receptor 1A and serotonin receptor 5HT2B, respectively.	Nitrogen	21-22	5-hydroxytryptamine receptor 2B	Homo sapiens	150-155
27783521-2	2016	By alternately bubbling CO2 and N2 at a moderate conditions (30  C, 80 mL min-1), silica nanoparticles reversibly switch between amphipathic and hydrophilic as a result of the adsorption of ammonium (CO2) and the desorption of tertiary amine (N2).	Nitrogen	32-34	CD59 molecule (CD59 blood group)	Homo sapiens	74-79
27727156-7	2016	Nitrogen addition to the reaction mixture results in increase of the growth rate on {001} facets correlated with the rise in the concentration of sp3 type defects.	Nitrogen	0-8	Sp3 transcription factor	Homo sapiens	146-149
27904760-5	2016	The global changes in serum N- and O-linked glycan structures, especially the glycans that are not made by cancer cells such as B lymphocyte-derived IgG and liver-synthesized haptoglobin and alpha1 acid glycoprotein, suggest that glycans might be the long sought diagnostic biomarkers associated with system malfunction in the blood circulation of cancer patients.	Nitrogen	28-29	haptoglobin	Homo sapiens	175-186
27811964-5	2016	Pathway enrichment and topology analysis identified that nitrogen metabolism, glycine, serine and threonine metabolism, aminoacyl-tRNA biosynthesis and taurine and hypotaurine metabolism were enriched after PARP inhibition in all three breast cancer cell lines.	Nitrogen	57-65	poly(ADP-ribose) polymerase 1	Homo sapiens	207-211
27749040-1	2016	Preparation of a range of enantioenriched beta-fluoro amines (alpha,beta-disubstituted) is described in which the nitrogen and fluorine atoms are attached to sp3-hybridized carbons.	Nitrogen	114-122	Sp3 transcription factor	Homo sapiens	158-161
27124387-1	2016	In forests of the humid subtropics of China, chronically elevated nitrogen (N) deposition, predominantly as ammonium (NH4+ ), causes significant nitrate (NO3- ) leaching from well-drained acid forest soils on hill slopes (HS), whereas significant retention of NO3- occurs in near-stream environments (groundwater discharge zones, GDZ).	Nitrogen	66-74	NBL1, DAN family BMP antagonist	Homo sapiens	154-157
27124387-1	2016	In forests of the humid subtropics of China, chronically elevated nitrogen (N) deposition, predominantly as ammonium (NH4+ ), causes significant nitrate (NO3- ) leaching from well-drained acid forest soils on hill slopes (HS), whereas significant retention of NO3- occurs in near-stream environments (groundwater discharge zones, GDZ).	Nitrogen	66-74	NBL1, DAN family BMP antagonist	Homo sapiens	260-263
26455908-0	2016	Downregulation of nitrogen permease regulator like-2 activates PDK1-AKT1 and contributes to the malignant growth of glioma cells.	Nitrogen	18-26	AKT serine/threonine kinase 1	Homo sapiens	68-72
27355518-7	2016	Enrichment of (15)N and (18)O in nitrate is consistent with lithotrophic denitrification of NO3 in the presence of dissolved Mn and Fe.	Nitrogen	18-19	NBL1, DAN family BMP antagonist	Homo sapiens	92-95
27704852-2	2016	An oxadiazolone-enabled approach is reported for convenient entry into N-unsubstituted 1-aminoisoquinolines through Co(III)-catalyzed redox-neutral, step-, atom-, and purification-economic C-H functionalization with alkynes.	Nitrogen	71-72	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	116-122
27799771-4	2016	The nanoparticles exhibited high cell uptake and Notch1 gene knockdown efficiency in SKOV3 cells at an nitrogen-to-phosphate ratio of 100 and an siRNA concentration of 50 nM.	Nitrogen	103-111	notch receptor 1	Homo sapiens	49-55
27711800-1	2016	Paradoxically, N- and O-donor substituted tri-arylphosphanes are shown to be weaker donors than PPh3 when binding the soft Lewis acid moiety [PPh2]+.	Nitrogen	15-16	caveolin 1	Homo sapiens	96-100
27830030-3	2016	By data mining a public dataset of rectal cancer transcriptome (GSE35452) from Gene Expression Omnibus, National Center of Biotechnology Information (GEO, NCBI), we identified that VNN1 was the most significantly upregulated gene among those related to nitrogen compound metabolic process (GO:0006807).	Nitrogen	253-261	vanin 1	Homo sapiens	181-185
27702902-1	2016	Natural abundance nitrogen and oxygen isotopes of nitrate (delta15NNO3 and delta18ONO3) provide an important tool for evaluating sources and transformations of natural and contaminant nitrate (NO3-) in the environment.	Nitrogen	18-26	NBL1, DAN family BMP antagonist	Homo sapiens	67-70
27693351-4	2016	Instead, the ICL is unhooked when one of the two N-glycosyl bonds forming the cross-link is cleaved by the DNA glycosylase NEIL3.	Nitrogen	49-50	nei-like DNA glycosylase 3 L homeolog	Xenopus laevis	123-128
29964426-1	2016	Based on test results and mass balance, PHA, TP metabolic regularity was revealed under different nitrate nitrogen concentrations in main anoxic stage [c(NO3)] for nitrogen and phosphorus removal in single sludge system with continuous flow, then the effectiveness of using c(NO3) as control parameter was proved from the perspective of the reaction mechanism.	Nitrogen	164-172	NBL1, DAN family BMP antagonist	Homo sapiens	154-157
27314899-9	2016	This study demonstrates that subaqueous nitrification of organic N in the aquifer, as opposed to in soils, might be a previously unrecognized source of NO3(-) to karst groundwater or other oxic groundwater systems.	Nitrogen	65-66	NBL1, DAN family BMP antagonist	Homo sapiens	152-155
27603495-0	2016	Copper-Catalyzed Inter/Intramolecular N-Alkenylation of Benzimidazoles via Tandem Processes Involving Selectively Mild Iodination of sp3 C-H Bond at alpha-Position of Ester.	Nitrogen	38-39	Sp3 transcription factor	Homo sapiens	133-136
27603495-1	2016	Inter/intramolecular approaches to sp2 C-N bond formation of N-alkenyl benzimidazoles have been accomplished in the presence of an iodide anion associated with a copper catalyst.	Nitrogen	41-42	Sp2 transcription factor	Homo sapiens	35-38
27533452-0	2016	O-mannosylation and N-glycosylation: two coordinated mechanisms regulating the tumour suppressor functions of E-cadherin in cancer.	Nitrogen	20-21	cadherin 1	Homo sapiens	110-120
27310287-2	2016	Herein, we demonstrate the feasibility of acquiring high S/N ratio natural-abundance 13 C NMR spectrum of a small amount of sample ( 2.0 mg) by using multiple-contact cross polarization (MCP) under ultrafast MAS.	Nitrogen	59-60	CD46 molecule	Homo sapiens	187-190
27533452-7	2016	Overall, our results reveal a newly identified mechanism of (dys)regulation of E-cadherin that occur through the interplay between O-mannosylation and N-glycosylation pathway.	Nitrogen	151-152	cadherin 1	Homo sapiens	79-89
30246999-2	2016	The results showed that ammonia nitrogen concentration decreased from 45.3 to 2.7 mg L-1 after aerobic, and nitrite nitrogen concentration increased from 0.01 to 19.6 mg L-1, while nitrite nitrogen concentration decreased from 19.6 to 1.2 mg L-1 after anoxic, which means that rapid nitrification and denitrification are successfully achieved.	Nitrogen	32-40	L1 cell adhesion molecule	Homo sapiens	85-88
27314477-8	2016	Partial digestion with PNGase F indicated that the three N-glycosylation sites of recA1AT, like the native A1AT protein in plasma, are occupied.	Nitrogen	24-25	serpin family A member 1	Homo sapiens	85-89
27547863-2	2016	According to the predicted topological structure, hPepT1 contains multiple asparagine residues in putative N-glycosylation sites.	Nitrogen	107-108	solute carrier family 15 member 1	Homo sapiens	50-56
27547863-3	2016	This study investigated the influence of the six putative N-glycosylation sites within the extracellular region between transmembrane domains 9 and 10 on hPepT1 transporter function and expression in HEK-293T cells.	Nitrogen	58-59	solute carrier family 15 member 1	Homo sapiens	154-160
27547863-4	2016	Our study confirmed that hPepT1 is N-glycosylated in HEK-293T cells with the glycosylated and fully deglycosylated isoforms exhibiting apparent molecular masses of ~78 and ~55 kDa, respectively.	Nitrogen	35-36	solute carrier family 15 member 1	Homo sapiens	25-31
27547863-6	2016	We also constructed multiple N-glycosylation mutants based on the hPepT1-N562Q mutant by mutagenizing the additional asparagine residues N404Q, N408Q, N439Q, N509Q, and N514Q.	Nitrogen	29-30	solute carrier family 15 member 1	Homo sapiens	66-72
27547863-10	2016	In summary, we provide the first molecular evidence that hPepT1 is modified by N-glycosylation and that all six asparagine residues in the large extracellular loop between transmembrane domains 9 and 10 are subject to N-glycosylation.	Nitrogen	79-80	solute carrier family 15 member 1	Homo sapiens	57-63
27547863-10	2016	In summary, we provide the first molecular evidence that hPepT1 is modified by N-glycosylation and that all six asparagine residues in the large extracellular loop between transmembrane domains 9 and 10 are subject to N-glycosylation.	Nitrogen	218-219	solute carrier family 15 member 1	Homo sapiens	57-63
27565667-5	2016	Inhibition of N-glycosylation by tunicamycin indicated that N-glycosylation of S2-expressed hFIX had occurred to a similar extent as in the CHO-produced hFIX.	Nitrogen	14-15	coagulation factor IX	Homo sapiens	92-96
27565667-5	2016	Inhibition of N-glycosylation by tunicamycin indicated that N-glycosylation of S2-expressed hFIX had occurred to a similar extent as in the CHO-produced hFIX.	Nitrogen	60-61	coagulation factor IX	Homo sapiens	92-96
27457784-9	2016	Further, incubations of M11 with recombinant P450s showed that M12 is formed via N-dealkylation of M11 by CYP3A4, CYP2C19, and CYP1A2.	Nitrogen	81-82	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	106-112
30246999-2	2016	The results showed that ammonia nitrogen concentration decreased from 45.3 to 2.7 mg L-1 after aerobic, and nitrite nitrogen concentration increased from 0.01 to 19.6 mg L-1, while nitrite nitrogen concentration decreased from 19.6 to 1.2 mg L-1 after anoxic, which means that rapid nitrification and denitrification are successfully achieved.	Nitrogen	116-124	L1 cell adhesion molecule	Homo sapiens	170-173
30246999-2	2016	The results showed that ammonia nitrogen concentration decreased from 45.3 to 2.7 mg L-1 after aerobic, and nitrite nitrogen concentration increased from 0.01 to 19.6 mg L-1, while nitrite nitrogen concentration decreased from 19.6 to 1.2 mg L-1 after anoxic, which means that rapid nitrification and denitrification are successfully achieved.	Nitrogen	116-124	L1 cell adhesion molecule	Homo sapiens	170-173
30246999-2	2016	The results showed that ammonia nitrogen concentration decreased from 45.3 to 2.7 mg L-1 after aerobic, and nitrite nitrogen concentration increased from 0.01 to 19.6 mg L-1, while nitrite nitrogen concentration decreased from 19.6 to 1.2 mg L-1 after anoxic, which means that rapid nitrification and denitrification are successfully achieved.	Nitrogen	116-124	L1 cell adhesion molecule	Homo sapiens	170-173
30246999-2	2016	The results showed that ammonia nitrogen concentration decreased from 45.3 to 2.7 mg L-1 after aerobic, and nitrite nitrogen concentration increased from 0.01 to 19.6 mg L-1, while nitrite nitrogen concentration decreased from 19.6 to 1.2 mg L-1 after anoxic, which means that rapid nitrification and denitrification are successfully achieved.	Nitrogen	116-124	L1 cell adhesion molecule	Homo sapiens	170-173
27056577-4	2016	The qPCR analyses of genes involved in nitrogen utilization showed that transcriptional levels of the UGA1 and DUR3 genes encoding GABA transaminase and urea transporter, respectively, are severely decreased in the AY77 cells.	Nitrogen	39-47	Dur3p	Saccharomyces cerevisiae S288C	111-115
27208798-6	2016	Moreover, the mice in the GLP-M and GLP-H groups had longer survival times compared with the mice in the TCG and PCG.The levels of creatinine and serum blood urea nitrogen, which are up-regulated by cisplatin, were significantly reduced by GLP-M and GLP-H.	Nitrogen	163-171	psoriasis susceptibility 1 candidate 2 (human)	Mus musculus	113-116
27519409-9	2016	Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris.	Nitrogen	188-196	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	0-5
29726164-6	2016	Catalase activity increased with the soil layer deepening, which was directly related to soil total potassium, and indirectly related to pH, organic matter, total nitrogen and total phosphorus through total potassium.	Nitrogen	163-171	catalase	Homo sapiens	0-8
27722238-3	2016	Gas transport studies showed that BILP-101/PIM-1 membranes exhibit high CO2 permeability (7200 Barrer) and selectivity over N2 (15).	Nitrogen	124-126	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	43-48
27400799-5	2016	At the early stage of AKI, serum miR-146b levels exhibited a rapid increase that was even faster than that of two conventional renal function indexes: serum creatinine and blood urea nitrogen levels.	Nitrogen	183-191	microRNA 146b	Rattus norvegicus	33-41
32263500-4	2016	Then, an mTiO2:N/Au hybrid structure was prepared through depositing Au nanoparticles on the surface of the mTiO2:N film and this acted as the photoelectrochemical matrix to immobilize the complementary DNA (cDNA) of the CEA aptamer probe (pDNA).	Nitrogen	15-16	CEA cell adhesion molecule 3	Homo sapiens	221-224
27519409-4	2016	Mxr1p regulates the expression of several genes involved in the utilization of amino acids as the sole source of carbon and nitrogen.	Nitrogen	124-132	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	0-5
27746942-2	2016	The CoII ion is coordinated in a slightly distorted trigonal-bipyramidal environment which is defined by three O atoms occupying the equatorial plane and the N and Cl atoms in the apical sites.	Nitrogen	158-159	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
27519409-9	2016	Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris.	Nitrogen	188-196	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	15-20
27519409-9	2016	Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris.	Nitrogen	188-196	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	15-20
27641064-0	2016	N-Glycosylation of integrin alpha5 acts as a switch for EGFR-mediated complex formation of integrin alpha5beta1 to alpha6beta4.	Nitrogen	0-1	epidermal growth factor receptor	Bos taurus	56-60
27641064-2	2016	We previously reported that the N-glycosylations of the calf domain on integrin alpha5 (S3-5,10-14) are essential for its inhibitory effect on EGFR signaling in regulating cell proliferation.	Nitrogen	32-33	epidermal growth factor receptor	Bos taurus	143-147
27641064-6	2016	Mechanistically, this N-glycosylation inhibited the response abilities upon EGF stimulation and EGFR dimerization.	Nitrogen	22-23	epidermal growth factor receptor	Bos taurus	96-100
27641064-7	2016	Interestingly, we found this N-glycosylation controlled the EGFR complex formation with integrin alpha5beta1 or alpha6beta4; i.e., the loss of site-11 switched EGFR-alpha5beta1 to EGFR-alpha6beta4, which is well known to promote cellular signaling for cell growth.	Nitrogen	29-30	epidermal growth factor receptor	Bos taurus	60-64
27641064-7	2016	Interestingly, we found this N-glycosylation controlled the EGFR complex formation with integrin alpha5beta1 or alpha6beta4; i.e., the loss of site-11 switched EGFR-alpha5beta1 to EGFR-alpha6beta4, which is well known to promote cellular signaling for cell growth.	Nitrogen	29-30	epidermal growth factor receptor	Bos taurus	160-164
27641064-7	2016	Interestingly, we found this N-glycosylation controlled the EGFR complex formation with integrin alpha5beta1 or alpha6beta4; i.e., the loss of site-11 switched EGFR-alpha5beta1 to EGFR-alpha6beta4, which is well known to promote cellular signaling for cell growth.	Nitrogen	29-30	epidermal growth factor receptor	Bos taurus	160-164
27641064-9	2016	Taken together, these data clearly demonstrate that the site-11 N-glycosylation on alpha5 is most important for its inhibitory effect on EGFR signaling, which may provide a novel regulatory mechanism for crosstalks between integrins and EGFR.	Nitrogen	64-65	epidermal growth factor receptor	Bos taurus	137-141
27641064-9	2016	Taken together, these data clearly demonstrate that the site-11 N-glycosylation on alpha5 is most important for its inhibitory effect on EGFR signaling, which may provide a novel regulatory mechanism for crosstalks between integrins and EGFR.	Nitrogen	64-65	epidermal growth factor receptor	Bos taurus	237-241
27126996-8	2016	In line with this, CP-d/n-ATF5-S1 synergistically enhanced tumor cell apoptosis induced by the BH3-mimetic ABT263 and the death ligand TRAIL.	Nitrogen	1-2	TNF superfamily member 10	Homo sapiens	135-140
27585239-4	2016	Gas adsorption studies indicated that cage 1 exhibited high CO2/N2 selectivity of 106.	Nitrogen	64-66	cancer antigen 1	Homo sapiens	38-44
27428465-4	2016	The saturated NHC Dipp2 SIm reacted in a 2:2 ratio yielding an NHC ring-expanded product at room temperature forming a six-membered -B-C=N-C=C-N- ring via C-N bond cleavage and further migration of the hydrides from two HBcat molecules to the former carbene-carbon atom.	Nitrogen	14-15	nudix hydrolase 4	Homo sapiens	18-23
27344261-2	2016	However, the TC/EA IRMS method can produce inaccurate delta(2)HVSMOW-SLAP results when analyzing nitrogen-bearing organic substances owing to the formation of hydrogen cyanide (HCN), leading to non-quantitative conversion of a sample into molecular hydrogen (H2) for IRMS analysis.	Nitrogen	97-105	Src like adaptor	Homo sapiens	69-73
27349833-7	2016	Our results show that the food-sourced CNP had various metabolic fluxes through urban systems, with carbon mostly emitted into the air and nitrogen and phosphorus mostly discharged into landfills and water.	Nitrogen	139-147	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	39-42
27593275-8	2016	Combined, our results suggests that unproductive northern boreal lakes currently have low potential for denitrification but are susceptible to small changes in NO3 loading especially if these are accompanied by enhanced C and P availability, likely promoting higher N2O production relative to N2.	Nitrogen	266-268	NBL1, DAN family BMP antagonist	Homo sapiens	160-163
29732863-6	2016	The post-anthesis dry matter and N accumulation accounted for 63.0%, 20.1% and 73.3%, 20.5% for the BSX and BMX treatments, respectively, while these proportions for the WDX were 59.3% and 11.6%, respectively.	Nitrogen	33-34	brain specific homeobox	Homo sapiens	100-103
27488762-5	2016	Transcriptome data analysis revealed that DHFR was up-regulated by nitrogen exhaustion, when Mort.	Nitrogen	67-75	dihydrofolate reductase	Escherichia coli	42-46
27312705-9	2016	Our findings demonstrate a clear pro-inflammatory function for NS-398 in the IL-1beta-mediated inflammatory response of granulosa cells, at least in part, owing to its augmenting effect on the IL-1beta-induced activation of NF-kappaB.	Nitrogen	63-65	interleukin 1 beta	Homo sapiens	77-85
27267252-3	2016	N-myristoylation lies upstream of multiple pro-proliferative and oncogenic pathways, but to date the complex substrate specificity of NMT has limited determination of which diseases are most likely to respond to a selective NMT inhibitor.	Nitrogen	0-1	N-myristoyltransferase 1	Homo sapiens	224-227
27556106-2	2016	Inhibition of the N-end rule pathway can lead to metabolic stabilization of proapoptotic protein fragments like RIPK1, thereby sensitizing cells to programmed cell death.	Nitrogen	18-19	receptor (TNFRSF)-interacting serine-threonine kinase 1	Mus musculus	112-117
27509490-1	2016	BACKGROUND: Glutamine synthetase (GS) is a crucial enzyme to the nitrogen cycle with great commercial and pharmaceutical value.	Nitrogen	65-73	glutamate-ammonia ligase	Homo sapiens	12-32
27506355-12	2016	In addition, we further applied our method to reveal, for the first time, the site-specific N-glycosylation profile of recombinant human acetylcholinesterase expressed in HEK293 cells.	Nitrogen	92-93	acetylcholinesterase (Cartwright blood group)	Homo sapiens	137-157
27441502-1	2016	To improve the selectivity, delivery, and activity of ferric (Fe) anticancer agents, we design prodrugs based on N-donor residues of the human serum albumin (HSA) carrier IIA subdomain.	Nitrogen	113-114	albumin	Homo sapiens	143-162
27505131-3	2016	Incorporation of Pbf-amides gives a racemization-free access to N-unprotected alpha-arylglycines.	Nitrogen	64-65	PTTG1 interacting protein	Homo sapiens	17-20
27515948-9	2016	Median Gal-9 levels were higher in patients with blood urea nitrogen to creatinine ratio (BUN/creatinine) &gt;=20 (mg/dL) than in patients with BUN/creatinine &lt;20 (mg/dL) at day 0 (817.3 vs 576.2 pg/mL, P = 0.007).	Nitrogen	60-68	galectin 9	Homo sapiens	7-12
29964737-2	2016	The results indicated that when the influent F- concentration was in the range of 0-700 mg L-1, the nitrogen removal efficiency promoted with rising influent F- concentration.	Nitrogen	100-108	immunoglobulin kappa variable 1-16	Homo sapiens	91-94
29964739-5	2016	Finally, the average effluent total nitrogen concentration was 10 mg L-1, with total nitrogen volume load of ANAMMOX system of 0.36 kg (m3 d)-1.	Nitrogen	36-44	immunoglobulin kappa variable 1-16	Homo sapiens	69-72
29964739-7	2016	The nitrogen of municipal wastewater could be stable and efficiently removed by the shortcut nitrification -ANAMMOX integration ABR with temperature of 30C and dissolved oxygen of 1-2 mg L-1.	Nitrogen	4-12	immunoglobulin kappa variable 1-16	Homo sapiens	187-190
29964741-4	2016	The results showed that a One-stage Autotrophic Nitrogen Removal Process was successfully established in 83 days under the following conditions: temperature at (30+-2)C , pH at 7.8-8.2, dissolved oxygen (DO) at 0.2-1.1mg L-1 and upflow velocity at 2.0-4.0m h-1.	Nitrogen	48-56	immunoglobulin kappa variable 1-16	Homo sapiens	221-224
27347808-3	2016	The current work harnesses density functional theoretical methods to provide insight into the electronic structure, formation, and N-H insertion reactivity of an iron porphyrin carbene, [Fe(Por)(SCH3)(CHCO2Et)](-), a model of a complex believed to exist in an experimentally studied artificial metalloenzyme.	Nitrogen	131-132	cytochrome p450 oxidoreductase	Homo sapiens	190-193
25737032-4	2016	Pazopanib can be well docked into the activity cavity of CYP3A4, and the interaction structure in pazopanib was methyl group located besides nitrogen in the five-membered ring.	Nitrogen	141-149	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	57-63
27312705-9	2016	Our findings demonstrate a clear pro-inflammatory function for NS-398 in the IL-1beta-mediated inflammatory response of granulosa cells, at least in part, owing to its augmenting effect on the IL-1beta-induced activation of NF-kappaB.	Nitrogen	63-65	interleukin 1 beta	Homo sapiens	193-201
27622181-10	2016	CONCLUSIONS: Pamidronate, N-containing second generation BPs, was safe in metabolism of IVD in vitro maintaining chondrogenic phenotype and matrix synthesis, and down-regulated TNF-alpha induced MMPs expression.	Nitrogen	2-3	tumor necrosis factor	Homo sapiens	177-186
26868756-7	2016	The N-glycan structures that were presented on all of the four occupied N-glycosylation sites of recombinant GC in NbGNTI-RNAi plants (GC(gnt1) ) showed that the majority (ranging from 73.3% up to 85.5%) of the N-glycans had mannose-type structures lacking potential immunogenic beta1,2-xylose and alpha1,3-fucose epitopes.	Nitrogen	4-5	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	138-142
27233528-9	2016	Furthermore, a simple regression analysis has shown that serum PTX3 concentrations in patients with T2DM were negatively correlated with body mass index, and positively correlated with blood urea nitrogen, serum creatinine, and UAE.	Nitrogen	196-204	pentraxin 3	Homo sapiens	63-67
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	leucyl and cystinyl aminopeptidase	Homo sapiens	174-250
27297967-4	2016	Mutant MRP1 lacking N-linked glycosylation [Asn19/23/1006Gln; sugar-free (SF)-MRP1] expressed in either HEK293 or HeLa cells had low Km and Vmax values for As(GS)3, similar to HeLa wild-type (WT) MRP1.	Nitrogen	20-21	ATP binding cassette subfamily C member 1	Homo sapiens	7-11
26186269-0	2016	Design, synthesis and preliminary structure-activity relationship investigation of nitrogen-containing chalcone derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors: a further study based on Flavokawain B Mannich base derivatives.	Nitrogen	83-91	acetylcholinesterase (Cartwright blood group)	Homo sapiens	127-147
27216994-8	2016	Finally, using mutant recombinant GluN subunits expressed in HEK293 cells, we found that 11 out of 12 predicted N-glycosylation sites in GluN1 and 7 out of 7 N-glycosylation sites in GluN2B are occupied by N-glycans.	Nitrogen	37-38	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	137-142
27216994-8	2016	Finally, using mutant recombinant GluN subunits expressed in HEK293 cells, we found that 11 out of 12 predicted N-glycosylation sites in GluN1 and 7 out of 7 N-glycosylation sites in GluN2B are occupied by N-glycans.	Nitrogen	112-113	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	137-142
27216994-13	2016	Furthermore, we found that 11 out of 12 predicted N-glycosylation sites in GluN1 and 7 out of 7 N-glycosylation sites in GluN2B are occupied by N-glycans.	Nitrogen	50-51	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	75-80
27411448-4	2016	In addition, Arabidopsis acr11 mutants have lost the capability to control Fd-GOGAT levels in response to light/dark diurnal cycles, nitrogen inputs, and changes in photorespiratory activity.	Nitrogen	133-141	uridylyltransferase-like protein	Arabidopsis thaliana	25-30
27208107-3	2016	Nitrogen and oxygen isotope ratios of nitrite (delta(15)NNO2- and delta(18)ONO2-, respectively) are geochemical tracers for evaluating the sources and the in situ rate of nitrite turnover determined from the activities of nitrification and denitrification; however, the isotope ratios of nitrite from archaeal ammonia oxidation have been characterized only for a few marine species.	Nitrogen	0-8	membrane frizzled-related protein	Homo sapiens	56-60
27356208-5	2016	In this work, a computational approach was conducted to select suitable location(s) for introducing new N-glycosylation sites into the human coagulation factor IX (hFIX).	Nitrogen	104-105	coagulation factor IX	Homo sapiens	141-162
27033522-8	2016	Mass spectrometry detected asparagine (N)-glycosylation on the secreted PEBP4.	Nitrogen	38-41	phosphatidylethanolamine binding protein 4	Homo sapiens	72-77
27023807-5	2016	The NH4 (+)-N/NO3 (-)-N ratio in rainfall averaged 1.2.	Nitrogen	18-23	NBL1, DAN family BMP antagonist	Homo sapiens	14-17
26954163-5	2016	The non-protein-nitrogen contents varied from 0.33% to 0.62% among different milk species.	Nitrogen	16-24	Weaning weight-maternal milk	Bos taurus	77-81
26873173-0	2016	Insights on N-glycosylation of human haptoglobin and its association with cancers.	Nitrogen	12-13	haptoglobin	Homo sapiens	37-48
27356208-5	2016	In this work, a computational approach was conducted to select suitable location(s) for introducing new N-glycosylation sites into the human coagulation factor IX (hFIX).	Nitrogen	104-105	coagulation factor IX	Homo sapiens	164-168
27356208-6	2016	With this aim, the first 45 residues of mature hFIX were explored to find out suitable positions for introducing either Asn or Ser/Thr residues, to create new N-glycosylation site(s).	Nitrogen	159-160	coagulation factor IX	Homo sapiens	47-51
27297056-3	2016	(Proteomics 2016, 16, 1872-1880) present data indicating that a glycoproteomics approach can detect N-glycosylated membrane protein differences between non-HIV-infected and latently infected human CD4(+) T-cell lines, identifying 172 proteins differentially expressed by these cells.	Nitrogen	100-101	CD4 molecule	Homo sapiens	197-200
27246700-1	2016	N-glycosylation of proteins is well known to occur at asparagine residues that fall within the canonical consensus sequence N-X-S/T but has also been identified at a small number of asparagine residues within N-X-C motifs, including the N491 residue of human serotransferrin.	Nitrogen	0-1	transferrin	Homo sapiens	259-274
27246700-3	2016	Alpha-1-acid glycoprotein (A1AG) and serotransferrin (Tf) were observed for the first time to be N-glycosylated on asparagine residues within a total of six unique noncanonical motifs.	Nitrogen	97-98	transferrin	Homo sapiens	37-52
27246700-4	2016	N-glycosylation was initially predicted in silico based on the evolutionary conservation of the N-X-C motif among related mammalian species and demonstrated experimentally in A1AG from porcine, canine, and feline sources and in human serotransferrin.	Nitrogen	0-1	transferrin	Homo sapiens	234-249
27224909-2	2016	In an effort to study the function and regulation of TMEM26 in breast cancer cells, we found that breast cancer cells express non-glycosylated and N-glycosylated isoforms of the TMEM26 protein and demonstrate that N-glycosylation is important for its retention at the plasma membrane.	Nitrogen	147-148	transmembrane protein 26	Homo sapiens	53-59
27367692-2	2016	Based on a selectivity study, the SG-APTMS-N,N-EPANTf2 phase showed a perfect selectivity towards Zr(IV) at pH 4 as compared to other metallic ions, including gold [Au(III)], copper [Cu(II)], cobalt [Co(II)], chromium [Cr(III)], lead [Pb(II)], selenium [Se(IV)] and mercury [Hg(II)] ions.	Nitrogen	43-44	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	200-207
27374441-9	2016	The DNMT1, DNMT3a and DNMT3b levels in the CCI+NS group were increased significantly compared with that in the sham+NS group on the 14th day after surgery (all P&lt;0.05).	Nitrogen	47-49	DNA methyltransferase 3 alpha	Rattus norvegicus	11-17
27061986-4	2016	Here we describe a new class of potent S1PR1 agonists wherein the exocyclic nitrogen was moved away from the pyridine ring (e.g. 11c).	Nitrogen	76-84	sphingosine-1-phosphate receptor 1	Rattus norvegicus	39-44
27224909-2	2016	In an effort to study the function and regulation of TMEM26 in breast cancer cells, we found that breast cancer cells express non-glycosylated and N-glycosylated isoforms of the TMEM26 protein and demonstrate that N-glycosylation is important for its retention at the plasma membrane.	Nitrogen	147-148	transmembrane protein 26	Homo sapiens	178-184
27224909-2	2016	In an effort to study the function and regulation of TMEM26 in breast cancer cells, we found that breast cancer cells express non-glycosylated and N-glycosylated isoforms of the TMEM26 protein and demonstrate that N-glycosylation is important for its retention at the plasma membrane.	Nitrogen	214-215	transmembrane protein 26	Homo sapiens	53-59
27224909-3	2016	Fulvestrant induced significant changes in expression and in the N-glycosylation status of TMEM26.	Nitrogen	65-66	transmembrane protein 26	Homo sapiens	91-97
28955897-4	2016	The affinity of the peptides for binding CaM followed the trend Baa (210+-10 pM)&lt;(7-aza)Trp-Baa (109+-5 pM)&lt;(2,7-aza)Trp-Baa (45+-2 pM), showing moderate increase in binding affinity upon increasing the number of nitrogen atoms in the Trp analogue.	Nitrogen	219-227	calmodulin 1	Homo sapiens	41-44
27314333-4	2016	Using chemical inhibitors, deglycosylase and site-directed mutagenesis, we found that human Rspo1 and Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosylated at N160, a position near the N-terminus of TSR1 domain.	Nitrogen	117-118	R-spondin 2	Homo sapiens	202-207
27314333-4	2016	Using chemical inhibitors, deglycosylase and site-directed mutagenesis, we found that human Rspo1 and Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosylated at N160, a position near the N-terminus of TSR1 domain.	Nitrogen	117-118	TSR1 ribosome maturation factor	Homo sapiens	269-273
27314333-6	2016	Introduction of the N-glycosylation site to Rspo2 mutant at the position homologous to N137 in Rspo1 restored full glycosylation and rescued the accumulation defect of nonglycosylated Rspo2 mutant in media.	Nitrogen	20-21	R-spondin 2	Homo sapiens	44-49
27314333-6	2016	Introduction of the N-glycosylation site to Rspo2 mutant at the position homologous to N137 in Rspo1 restored full glycosylation and rescued the accumulation defect of nonglycosylated Rspo2 mutant in media.	Nitrogen	20-21	R-spondin 2	Homo sapiens	184-189
27314333-7	2016	Similar effect can be observed in the N137 Rspo1 or Rspo3 mutant engineered with Rspo2 N-glycosylation site.	Nitrogen	38-39	R-spondin 2	Homo sapiens	81-86
27294964-6	2016	The highest selectivity alpha (CO2/N2) = 15.5 was achieved for CS-b-PAN/[bmim][BF4].	Nitrogen	35-37	chorionic somatomammotropin hormone 2	Homo sapiens	63-67
27278520-9	2016	The number of CD4(+)CD25(+) cells was negatively related to blood urea nitrogen, serum uric acid, proteinuria, and supernatant IL-4; whereas positively associated with estimated glomerular filtration rate in patients.	Nitrogen	71-79	CD4 molecule	Homo sapiens	14-17
28955897-5	2016	The increased binding affinity may be due to the formation of more hydrogen bonds upon binding CaM for the Trp analogue with more nitrogen atoms.	Nitrogen	130-138	calmodulin 1	Homo sapiens	95-98
27106134-0	2016	A High-Performance WSe2 /h-BN Photodetector using a Triphenylphosphine (PPh3 )-Based n-Doping Technique.	Nitrogen	15-16	caveolin 1	Homo sapiens	72-76
27313575-0	2016	Efficiency of N2 Gas Flushing Compared to the Lactoperoxidase System at Controlling Bacterial Growth in Bovine Raw Milk Stored at Mild Temperatures.	Nitrogen	14-16	Weaning weight-maternal milk	Bos taurus	115-119
27313575-2	2016	N2 gas flushing of raw milk has shown great potential to control bacterial growth in a temperature range of 6-12 C without promoting undesired side effects.	Nitrogen	0-2	Weaning weight-maternal milk	Bos taurus	23-27
27313575-5	2016	This study shows that N2 gas flushing, which inhibited bacterial growth in raw milk at 15 and 25 C for 24 and 12 h, respectively, could constitute an alternative to LPs where no cold storage facilities exist, especially as a replacement for adulterating substances.	Nitrogen	22-24	Weaning weight-maternal milk	Bos taurus	79-83
26303959-8	2016	GmCZ-SOD1 gene was induced significantly in soybean root under low nitrogen stress.	Nitrogen	67-75	superoxide dismutase [Cu-Zn]	Glycine max	5-9
27252617-3	2016	MTDL-2 showed more high affinity toward the four enzymes than MTDL-1.MTDL-3 and MTDL-4, were designed containing the N-benzylpiperidinium moiety from Donepezil, a metal- chelating 8-hydroxyquinoline group and linked to a N-propargyl core and they were pharmacologically evaluated.The presence of the cyano group in MTDL-3, enhanced binding to AChE, BuChE and MAO A.	Nitrogen	117-118	acetylcholinesterase (Cartwright blood group)	Homo sapiens	343-347
26819318-2	2016	Here, we demonstrate that human CCR7 is N-glycosylated on 2 specific residues in the N terminus and the third extracellular loop.	Nitrogen	40-41	C-C motif chemokine receptor 7	Homo sapiens	32-36
27208309-10	2016	Similar to Arabidopsis, we found that mutation of the BT1/BT2 ortholog gene in rice (Oryza sativa) OsBT increased NUE by 20% compared to wild-type rice plants under low nitrogen conditions.	Nitrogen	169-177	BTB and TAZ domain protein 1	Arabidopsis thaliana	54-57
27223297-4	2016	The N-glycosylation profile and significance in viral infection via DC-SIGN have not been elucidated.	Nitrogen	4-5	CD209 molecule	Homo sapiens	68-75
26909705-9	2016	Our analyses indicate that yield scaled N2O emissions and NO3 leaching indicate possible improvements of nitrogen use efficiencies in European farming systems.	Nitrogen	105-113	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
27227887-5	2016	These phenotypes were rescued by TORC1 inhibition using pharmacological or genetic means, and the loss of Lam2, Gtr1, Gtr2, Npr2 or Npr3 disinhibited TORC1 activity under nitrogen depletion, as measured by Rps6 phosphorylation.	Nitrogen	171-179	Npr3p	Saccharomyces cerevisiae S288C	132-136
27506021-3	2016	The results showed that: (1) NO3--N pollution was the main inorganic nitrogen pollution in Beijing rivers and pollution of downstream was more serious than that of upstream.	Nitrogen	69-77	NBL1, DAN family BMP antagonist	Homo sapiens	29-32
27506043-3	2016	Nitrite nitrogen kept accumulating up to 800 mg   L-1 when the influent COD/TN ratio was 0.8 +- 0.2, and the removal rates of TN, ammonium nitrogen and total organic carbon (TOC) were only 18.3% +- 12.2%, 84.2% +- 10.3% and 60.7% +- 10.7%, respectively.	Nitrogen	8-16	immunoglobulin kappa variable 1-16	Homo sapiens	50-53
27506043-4	2016	By contrast, as the influent COD/ TN ratio was increased to 2.4 +- 0.5, the accumulated concentration of nitrite nitrogen sharply decreased from 800 mg   L-1 to below 10 mg-L-1, and the removal rates of TN, ammonium nitrogen and TOC were increased to over 90%, 95% and 85%, respectively.	Nitrogen	113-121	immunoglobulin kappa variable 1-16	Homo sapiens	154-157
27506043-4	2016	By contrast, as the influent COD/ TN ratio was increased to 2.4 +- 0.5, the accumulated concentration of nitrite nitrogen sharply decreased from 800 mg   L-1 to below 10 mg-L-1, and the removal rates of TN, ammonium nitrogen and TOC were increased to over 90%, 95% and 85%, respectively.	Nitrogen	113-121	immunoglobulin kappa variable 1-16	Homo sapiens	173-176
27032077-11	2016	UGT1A9, an abundant UGT isoform expressed in human liver and kidney, preferentially forms the O-linked Gluc conjugates of HONH-AalphaC and HONH-PhIP as opposed to their detoxicated N(2)-Gluc isomers.	Nitrogen	181-185	beta-1,3-glucuronyltransferase 2	Homo sapiens	0-3
27506019-6	2016	The concentration of the dissolved inorganic nitrogen was higher than 0.30 mg   L-1, and the value of N/P was higher than 60, which indicated that PO43--P was the nutrient limiting phytoplankton growth in the tidal reach and estuary of the Daliao river in August and November, 2013.	Nitrogen	45-53	immunoglobulin kappa variable 1-16	Homo sapiens	80-83
27009754-3	2016	OBJECTIVES: We investigated the associations of serum n-6 PUFAs and activities of enzymes involved in PUFA metabolism, Delta5 desaturase (D5D) and Delta6 desaturase (D6D), with T2D risk to determine whether serum zinc concentrations could modify these associations.	Nitrogen	16-17	fatty acid desaturase 2	Homo sapiens	153-164
27009754-3	2016	OBJECTIVES: We investigated the associations of serum n-6 PUFAs and activities of enzymes involved in PUFA metabolism, Delta5 desaturase (D5D) and Delta6 desaturase (D6D), with T2D risk to determine whether serum zinc concentrations could modify these associations.	Nitrogen	16-17	fatty acid desaturase 2	Homo sapiens	166-169
26968544-7	2016	Additionally, the R71T mutation creates an ectopic N-linked glycosylation site that results in aberrant glycosylation of the extracellular domain of delta-sarcoglycan.	Nitrogen	51-52	sarcoglycan, delta	Rattus norvegicus	149-166
26982372-3	2016	Linking benzamide substrates with a rotatable C-N bond, we constructed a novel semirigid pyramid-like scaffold that could support its two-turn alpha-helix mimicry without aromatic stacking interactions and could adopt the different dihedral angles of the key residues of p53 and BH3-only peptides.	Nitrogen	48-49	tumor protein p53	Homo sapiens	271-274
27062198-7	2016	These studies with N-substituted SAHA analogs are consistent with the strategy exploiting the 14-A internal cavity of HDAC proteins to create HDAC1/2 selective inhibitors.	Nitrogen	19-20	histone deacetylase 1	Homo sapiens	142-147
26919319-9	2016	Additional field measurements within nitrogen-limited ponds indicated that nitrogen flux rates from the periphyton to the water column in high-snail density/high-infection ponds were up to 50% higher than low-infection ponds.	Nitrogen	37-45	snail family transcriptional repressor 1	Homo sapiens	143-148
26919319-9	2016	Additional field measurements within nitrogen-limited ponds indicated that nitrogen flux rates from the periphyton to the water column in high-snail density/high-infection ponds were up to 50% higher than low-infection ponds.	Nitrogen	75-83	snail family transcriptional repressor 1	Homo sapiens	143-148
27136596-2	2016	The formation of N-glycan branches catalyzed by specific N-acetylglucosaminyltransferases [GnT-III, GnT-IVs, GnT-V, GnT-IX (Vb)] and a fucosyltransferase, Fut8, provides functionally diverse N-glycosylated proteins.	Nitrogen	17-18	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	109-114
27136596-2	2016	The formation of N-glycan branches catalyzed by specific N-acetylglucosaminyltransferases [GnT-III, GnT-IVs, GnT-V, GnT-IX (Vb)] and a fucosyltransferase, Fut8, provides functionally diverse N-glycosylated proteins.	Nitrogen	17-18	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	116-122
27055393-1	2016	This work presents a novel fluorescent sensor for the determination of tacrine by combining the magnificent fluorescence properties of nitrogen-doped graphene quantum dots (N-GQDs) with the high potential of acetylcholinesterase (AChE) enzyme for screening its inhibitors.	Nitrogen	135-143	acetylcholinesterase (Cartwright blood group)	Homo sapiens	230-234
27015265-3	2016	Herein, we show the interest of vertically aligned nitrogen-doped carbon nanotube (VA-NCNT) electrodes for the required sensitive electrochemical detection of lysozyme in serum, a protein that is up-regulated in IBD.	Nitrogen	51-59	lysozyme	Homo sapiens	159-167
27548970-6	2016	After 93 d operation, the total nitrogen in effluent was stabilized below 50 mg   L-1, the total nitrogen removal efficiency reached 90%, and the removal rate reached 5 kg   (m3   d)-1.	Nitrogen	32-40	immunoglobulin kappa variable 1-16	Homo sapiens	82-85
26055553-4	2016	Compared with CCR5+/+ mice, CCR5-/- mice showed increased mortality and renal injury, including elevated creatinine and blood urea nitrogen levels, following LPS challenge.	Nitrogen	131-139	chemokine (C-C motif) receptor 5	Mus musculus	28-32
27032890-5	2016	Docking of the C10 analogues at the D3 receptor, suggest that an ionic interaction between the protonated nitrogen atom and Asp110, a H-bond interaction between the C2 phenol and Ser192, a H-bond interaction between the C10 phenol and Cys181 as well as hydrophobic interactions of the aryl rings to Phe106 and Phe345, are critical for high affinity of the compounds.	Nitrogen	106-114	homeobox C10	Homo sapiens	15-18
26471129-5	2016	However, after renal ischemia-reperfusion injury, Klf4 cKO mice exhibited elevated serum levels of urea nitrogen and creatinine and aggravated renal histology compared with those of Klf4 floxed controls.	Nitrogen	104-112	Kruppel-like factor 4 (gut)	Mus musculus	50-54
26964648-0	2016	Unveiling the Hybrid n-Si/PEDOT:PSS Interface.	Nitrogen	1-2	PSS	Homo sapiens	32-35
26964648-6	2016	Moreover, we show that even when storing the sample in inert gas such as, e.g., nitrogen the n-Si/SiOx/ PEDOT: PSS interface continues to further oxidize.	Nitrogen	80-88	PSS	Homo sapiens	111-114
26828122-0	2016	The human colonic thiamine pyrophosphate transporter (hTPPT) is a glycoprotein and N-linked glycosylation is important for its function.	Nitrogen	83-84	solute carrier family 44 member 4	Homo sapiens	54-59
26828122-3	2016	The hTPPT protein is predicted to have multiple TM domains with a number of putative N-glycosylation sites, but it is not known if the protein is actually glycosylated, and if so at which site, and their role in the functionality of the transporter.	Nitrogen	85-86	solute carrier family 44 member 4	Homo sapiens	4-9
26828122-4	2016	Using several approaches including inhibiting de novo N-glycosylation in human colonic epithelial NCM460 cells with tunicamycin as well as enzymatic de-glycosylation, we show that the hTPPT protein is, indeed, a glycoprotein.	Nitrogen	54-55	solute carrier family 44 member 4	Homo sapiens	184-189
26656560-0	2016	A novel mutation on the transferrin gene abolishes one N-glycosylation site and alters the pattern of transferrin isoforms, mimicking that observed after excessive alcohol consumption.	Nitrogen	55-56	transferrin	Homo sapiens	24-35
26189796-0	2016	Preventing E-cadherin aberrant N-glycosylation at Asn-554 improves its critical function in gastric cancer.	Nitrogen	31-32	cadherin 1	Homo sapiens	11-21
26947874-0	2016	Additional N-glycosylation in the N-terminal region of recombinant human alpha-1 antitrypsin enhances the circulatory half-life in Sprague-Dawley rats.	Nitrogen	11-12	serpin family A member 1	Homo sapiens	73-92
26189796-1	2016	E-cadherin is a central molecule in the process of gastric carcinogenesis and its posttranslational modifications by N-glycosylation have been described to induce a deleterious effect on cell adhesion associated with tumor cell invasion.	Nitrogen	117-118	cadherin 1	Homo sapiens	0-10
26668133-7	2016	TpoR activation was dependent on its extracellular domain and its N-glycosylation, especially at N117.	Nitrogen	66-67	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	0-4
27064874-1	2016	Proteins N-glycosylation is significantly increased in the activated human hepatic stellate cells (HSCs) stimulated by transforming growth factor-beta1 (TGF-beta1) compared to the quiescent HSCs according to our previous study.	Nitrogen	9-10	transforming growth factor beta 1	Homo sapiens	119-151
27064874-1	2016	Proteins N-glycosylation is significantly increased in the activated human hepatic stellate cells (HSCs) stimulated by transforming growth factor-beta1 (TGF-beta1) compared to the quiescent HSCs according to our previous study.	Nitrogen	9-10	transforming growth factor beta 1	Homo sapiens	153-162
26668133-9	2016	A soluble form of TpoR was able to prevent activation of full-length TpoR provided that it was N-glycosylated.	Nitrogen	95-96	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	18-22
26668133-9	2016	A soluble form of TpoR was able to prevent activation of full-length TpoR provided that it was N-glycosylated.	Nitrogen	95-96	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	69-73
26861551-2	2016	Exploration of 8-oxoadenine derivatives bearing saturated oxygen or nitrogen heterocycles in the N-9 substituent has revealed a remarkable selective enhancement in IFNalpha inducing potency in the nitrogen series.	Nitrogen	68-76	interferon alpha 1	Homo sapiens	164-172
26861551-2	2016	Exploration of 8-oxoadenine derivatives bearing saturated oxygen or nitrogen heterocycles in the N-9 substituent has revealed a remarkable selective enhancement in IFNalpha inducing potency in the nitrogen series.	Nitrogen	197-205	interferon alpha 1	Homo sapiens	164-172
27005614-6	2016	For example, cytosolic glutamine synthetase (GS1), heat shock protein 70 (Hsp70), and chloroplastic elongation factor G (cpEF-G) were involved in pigment-related nitrogen synthesis as well as protein synthesis and processing.	Nitrogen	162-170	glutamate-ammonia ligase	Homo sapiens	23-43
26822566-2	2016	The introduction of hydrophobic substituents on the nitrogen atom of the piperidine ring enhanced ERalpha binding affinity.	Nitrogen	52-60	estrogen receptor 1	Homo sapiens	98-105
27190601-3	2016	The corresponding N (2)-isomer 4k (N (2)-(4-bromobenzyl)quinazoline-2,4-diamine) was also able to prevent Abeta aggregation (Abeta40 IC50 = 1.7 muM).	Nitrogen	18-23	latexin	Homo sapiens	144-147
26877080-0	2016	Shoot-to-Root Mobile Transcription Factor HY5 Coordinates Plant Carbon and Nitrogen Acquisition.	Nitrogen	75-83	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	42-45
26877080-6	2016	We further show that HY5 function is fluence-rate modulated and enables homeostatic maintenance of carbon-nitrogen balance in different light environments.	Nitrogen	106-114	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	21-24
26877080-7	2016	Thus, mobile HY5 coordinates light-responsive carbon and nitrogen metabolism, and hence shoot and root growth, in a whole-organismal response to ambient light fluctuations.	Nitrogen	57-65	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	13-16
26822566-3	2016	In addition, the introduction of four methyl groups adjacent to the piperidine ring nitrogen atom remarkably enhanced ERalpha binding affinity.	Nitrogen	84-92	estrogen receptor 1	Homo sapiens	118-125
26827137-5	2016	The piperidine nitrogen was functionalized with carbamates, amides, and sulfonamides, providing compounds that are potent inverse agonists of hCB1 with good selectivity for hCB1 over hCB2.	Nitrogen	15-23	cannabinoid receptor 1	Homo sapiens	142-146
26827137-5	2016	The piperidine nitrogen was functionalized with carbamates, amides, and sulfonamides, providing compounds that are potent inverse agonists of hCB1 with good selectivity for hCB1 over hCB2.	Nitrogen	15-23	cannabinoid receptor 1	Homo sapiens	173-177
26508536-9	2016	While NO is an important signalling component in ABA-induced stomatal closure in Arabidopsis, our findings demonstrate a more complex interaction associating potassium nutrition and nitrogen metabolism in the nia1nia2 mutant that affects stomatal function.	Nitrogen	182-190	nitrate reductase 1	Arabidopsis thaliana	209-217
26449235-2	2016	The nitrogen-fixing cyanobacterium, Anabaena L-31 has two Hsp60 proteins, 59 kDa GroEL coded by the second gene of groESL operon and 61 kDa Cpn60 coded by cpn60 gene.	Nitrogen	4-12	GroEL	Escherichia coli	81-86
26272416-6	2016	Similarly to a laboratory strain, RPS26A transcription was repressed and Npr1 was dephosphorylated in K7 cells, indicative of the expected loss of TORC1 function under nitrogen starvation.	Nitrogen	168-176	ribosomal 40S subunit protein S26A	Saccharomyces cerevisiae S288C	34-40
26768840-4	2016	CNPrTEOS was characterized by FTIR spectroscopy, field-emission scanning electron microscopy and nitrogen gas adsorption.	Nitrogen	97-105	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	0-8
26856397-5	2016	Olanzapine N-demethylation and N-oxygenation were found to be catalyzed by CYP1A2 and CYP2D6 and by CYP2D6 and FMO3, respectively, in experiments using liver microsomes and recombinant enzymes.	Nitrogen	11-12	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	86-92
26856397-5	2016	Olanzapine N-demethylation and N-oxygenation were found to be catalyzed by CYP1A2 and CYP2D6 and by CYP2D6 and FMO3, respectively, in experiments using liver microsomes and recombinant enzymes.	Nitrogen	11-12	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	100-106
27114803-8	2016	RESULTS: Our results revealed that transplantation of Nrf2-overexpressed MSCs into AKI-induced rats decreased blood urea nitrogen and creatinine and ameliorated kidney regeneration throughout 14 days.	Nitrogen	121-129	NFE2 like bZIP transcription factor 2	Rattus norvegicus	54-58
26449235-0	2016	GroEL of the nitrogen-fixing cyanobacterium Anabaena sp.	Nitrogen	13-21	GroEL	Escherichia coli	0-5
26847380-0	2016	A multi-level quantum mechanics and molecular mechanics study of SN2 reaction at nitrogen: NH2Cl + OH(-) in aqueous solution.	Nitrogen	81-89	solute carrier family 38 member 5	Homo sapiens	65-68
26721884-12	2016	In contrast, mutations of NKCC2 N-glycosylation sites abolished the effects of OS9, indicating that OS9-induced protein degradation is N-glycan-dependent.	Nitrogen	26-27	OS9 endoplasmic reticulum lectin	Homo sapiens	79-82
26721884-12	2016	In contrast, mutations of NKCC2 N-glycosylation sites abolished the effects of OS9, indicating that OS9-induced protein degradation is N-glycan-dependent.	Nitrogen	26-27	OS9 endoplasmic reticulum lectin	Homo sapiens	100-103
26725718-4	2016	STUDY DESIGN: Activated THP-1 cells were exposed to .5 to 50 muM of nitrogen-containing bisphosphonates and .5 to 500 muM of clodronate.	Nitrogen	68-76	latexin	Homo sapiens	61-64
26520475-0	2016	Optimization, isotherm, kinetic and thermodynamic studies of Pb(II) ions adsorption onto N-maleated chitosan-immobilized TiO2 nanoparticles from aqueous media.	Nitrogen	89-90	submaxillary gland androgen regulated protein 3B	Homo sapiens	61-67
26901320-11	2016	More importantly, we show that the binding of Leg1a to FGFR relies on the glycosylation at the 70th asparagine (Asn(70) or N(70)), and mutating the Asn(70) to Ala(70) compromised Leg1"s function in liver development.	Nitrogen	123-124	liver-enriched gene 1, tandem duplicate 1	Danio rerio	46-51
26901320-11	2016	More importantly, we show that the binding of Leg1a to FGFR relies on the glycosylation at the 70th asparagine (Asn(70) or N(70)), and mutating the Asn(70) to Ala(70) compromised Leg1"s function in liver development.	Nitrogen	123-124	liver-enriched gene 1, tandem duplicate 1	Danio rerio	46-50
26663080-3	2016	Mxr1p is cytosolic in cells cultured in minimal medium containing a yeast nitrogen base, ammonium sulfate, and acetate (YNBA) but localizes to the nucleus of cells cultured in YNBA supplemented with glutamate or casamino acids as well as nutrient-rich medium containing yeast extract, peptone, and acetate (YPA).	Nitrogen	74-82	peptide-methionine-S-sulfoxide reductase	Saccharomyces cerevisiae S288C	0-5
26520475-1	2016	Chitosan, CS was chemically engineered by maleic anhydride via simple protocol to produce N-maleated chitosan, MCS which immobilized on anatase TiO2 to synthesize novel eco-friendly nanosorbent (51+-3.8 nm), MCS@TiO2 for cost-effective and efficient removal of Pb(II) ions from aqueous media.	Nitrogen	90-91	submaxillary gland androgen regulated protein 3B	Homo sapiens	261-267
26722818-1	2016	Aldehyde oxidase (AO), a cytosolic molybdenum-containing hydroxylase, is predominantly active in liver and other tissues of mammalian species and involved in the metabolism of extensive range of aldehydes and nitrogen-containing compounds.	Nitrogen	209-217	aldehyde oxidase 1	Homo sapiens	0-16
27363162-4	2016	The inorganic nitrogen was dominated by NO3- -N, which accounted for up to 57.4%-84.7% of inorganic nitrogen.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	40-43
27363162-4	2016	The inorganic nitrogen was dominated by NO3- -N, which accounted for up to 57.4%-84.7% of inorganic nitrogen.	Nitrogen	100-108	NBL1, DAN family BMP antagonist	Homo sapiens	40-43
26526764-1	2016	Nitric oxide (NO) is derived from multiple isoforms of the Nitric Oxide Synthases (NOSs) within the lung for a variety of functions; however, NOS2-derived nitrogen oxides seem to play an important role in inflammatory regulation.	Nitrogen	155-163	nitric oxide synthase 2, inducible	Mus musculus	142-146
26730681-1	2016	In this work, nitrogen-doped carbon nanoparticle (N-CNP) modulated turn-on fluorescent probes were developed for rapid and selective detection of histidine.	Nitrogen	14-22	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	52-55
26627857-3	2016	The addition of glucose to essential AA infusate did not stimulate milk protein yield or concentration, but reduced milk urea nitrogen by 17% and decreased milk fat yield.	Nitrogen	126-134	Weaning weight-maternal milk	Bos taurus	116-120
26627857-3	2016	The addition of glucose to essential AA infusate did not stimulate milk protein yield or concentration, but reduced milk urea nitrogen by 17% and decreased milk fat yield.	Nitrogen	126-134	Weaning weight-maternal milk	Bos taurus	116-120
26686718-0	2016	A model of milk production in lactating dairy cows in relation to energy and nitrogen dynamics.	Nitrogen	77-85	Weaning weight-maternal milk	Bos taurus	11-15
26686718-6	2016	Milk production and fetal growth are then calculated in relation to the overall energy and nitrogen dynamics.	Nitrogen	91-99	Weaning weight-maternal milk	Bos taurus	0-4
26637370-6	2016	These findings uniquely link N-linked glycosylation inhibition, ER stress, and ERK/AKT downregulation in endothelial cells, and provide a novel drug development strategy to overcome resistance mechanisms to currently available antiangiogenic agents.	Nitrogen	29-30	mitogen-activated protein kinase 1	Mus musculus	79-82
26637370-6	2016	These findings uniquely link N-linked glycosylation inhibition, ER stress, and ERK/AKT downregulation in endothelial cells, and provide a novel drug development strategy to overcome resistance mechanisms to currently available antiangiogenic agents.	Nitrogen	29-30	thymoma viral proto-oncogene 1	Mus musculus	83-86
26474750-0	2016	Transgenesis of humanized fat1 promotes n-3 polyunsaturated fatty acid synthesis and expression of genes involved in lipid metabolism in goat cells.	Nitrogen	3-4	protocadherin Fat 1	Capra hircus	26-30
26671614-1	2016	A solvothermal reaction of Zn(ii) salt with methanetetrabenzoic acid (H4MTB) and 1,4,8,11-tetraazacyclotetradecane (cyclam, CYC) created a new microporous metal-organic framework {[Zn2(mu4-MTB)(kappa(4)-CYC)2] 2DMF 7H2O}n (DMF = N,N"-dimethylformamide).	Nitrogen	22-23	cytochrome c, somatic	Homo sapiens	124-127
26671614-1	2016	A solvothermal reaction of Zn(ii) salt with methanetetrabenzoic acid (H4MTB) and 1,4,8,11-tetraazacyclotetradecane (cyclam, CYC) created a new microporous metal-organic framework {[Zn2(mu4-MTB)(kappa(4)-CYC)2] 2DMF 7H2O}n (DMF = N,N"-dimethylformamide).	Nitrogen	22-23	cytochrome c, somatic	Homo sapiens	203-206
27078951-4	2016	During the recession of runoff, more subsurface runoff would result in a concentration peak of total nitrogen (TN) and nitrogen (NO3- -N) .	Nitrogen	119-127	NBL1, DAN family BMP antagonist	Homo sapiens	129-132
27078951-7	2016	The average transport fluxes of TP, TN, NH4+ -N and NO3- -N were 34.10, 1195.55, 1006.62 and 52.38 g x hm(-2), respectively, and NO3- -N was the main nitrogen form and accounted for 84% of TN.	Nitrogen	150-158	NBL1, DAN family BMP antagonist	Homo sapiens	52-55
26751681-2	2016	This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways that provide energy and direct the flow of carbon and nitrogen.	Nitrogen	200-208	AKT serine/threonine kinase 1	Homo sapiens	52-55
26704699-1	2016	A transition-metal-free deacylative C(sp(3))-C(sp(2)) bond cleavage for the synthetically practical oxidative amination of ketones and aldehydes to nitriles is first described, using cheap and commercially abundant NaNO2 as the oxidant and the nitrogen source.	Nitrogen	244-252	regulator of calcineurin 2	Homo sapiens	45-52
26751681-2	2016	This effect is triggered via activation of the PI3K-Akt-mTOR pathway, and it is usually accompanied by the activation of other metabolic pathways that provide energy and direct the flow of carbon and nitrogen.	Nitrogen	200-208	mechanistic target of rapamycin kinase	Homo sapiens	56-60
26741368-4	2016	Methamphetamine-CYP3A4 docking showed that methamphetamine binds to the heme of CYP3A4 in two modes, both leading to N-demethylation.	Nitrogen	117-118	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	16-22
26741368-4	2016	Methamphetamine-CYP3A4 docking showed that methamphetamine binds to the heme of CYP3A4 in two modes, both leading to N-demethylation.	Nitrogen	117-118	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	80-86
26302035-8	2016	Milk urea nitrogen was increased at both time points in DDGS compared with CON cows (P&lt;0.01).	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
26751495-3	2016	While GlcAT-P is able to use N-linked N-acetyllactosamine chains and the O-linked T-antigen as a substrate to form non-sulfated HNK1- (GlcAbeta1-3Galbeta1-4GlcNAcbeta1-) and glucuronyl-T-antigens in vivo, GlcAT-S adds glucuronic acid only to N-linked chains, thereby synthesizing only the non-sulfated HNK1-antigen.	Nitrogen	29-30	Glucuronyltransferase P	Drosophila melanogaster	6-13
26751495-3	2016	While GlcAT-P is able to use N-linked N-acetyllactosamine chains and the O-linked T-antigen as a substrate to form non-sulfated HNK1- (GlcAbeta1-3Galbeta1-4GlcNAcbeta1-) and glucuronyl-T-antigens in vivo, GlcAT-S adds glucuronic acid only to N-linked chains, thereby synthesizing only the non-sulfated HNK1-antigen.	Nitrogen	38-39	Glucuronyltransferase P	Drosophila melanogaster	6-13
26730711-0	2016	N2 Gas Flushing Alleviates the Loss of Bacterial Diversity and Inhibits Psychrotrophic Pseudomonas during the Cold Storage of Bovine Raw Milk.	Nitrogen	0-2	Weaning weight-maternal milk	Bos taurus	137-141
26730711-2	2016	Culture-dependent methods indicated that the continuous N2 gas-flushing of raw milk reduced the bacterial growth during cold storage by up to four orders of magnitude, compared to cold storage alone.	Nitrogen	56-58	Weaning weight-maternal milk	Bos taurus	79-83
26730711-8	2016	Significant differences between cold-stored and additionally N2-flushed milk were mainly related to higher levels of Pseudomononadaceae (including the genera Pseudomonas and Acinetobacter) in cold-stored milk samples; furthermore, rare taxa were better preserved by the N2 gas flushing compared to the cold storage alone.	Nitrogen	61-63	Weaning weight-maternal milk	Bos taurus	72-76
26730711-8	2016	Significant differences between cold-stored and additionally N2-flushed milk were mainly related to higher levels of Pseudomononadaceae (including the genera Pseudomonas and Acinetobacter) in cold-stored milk samples; furthermore, rare taxa were better preserved by the N2 gas flushing compared to the cold storage alone.	Nitrogen	61-63	Weaning weight-maternal milk	Bos taurus	204-208
27885636-2	2016	In brain, GS is exclusively located in astrocytes where it serves to maintain the glutamate-glutamine cycle, as well as nitrogen metabolism.	Nitrogen	120-128	glutamate-ammonia ligase	Homo sapiens	10-12
26703262-6	2016	The phase separation was achieved by gentle bubbling of nitrogen stream (2 mL min(-1) during 2 min).	Nitrogen	56-64	CD59 molecule (CD59 blood group)	Homo sapiens	78-84
26887223-7	2016	Ammonium nitrate as nitrogen source supported the maximum activity of chitinase in both isolates, whereas urea was a poor nitrogen source.	Nitrogen	20-28	endochitinase A	Nicotiana tabacum	70-79
26687085-9	2016	Higher concentration of NO3 (-)-N in Xinzhuang and CODMn in Daguan indicated different controlling measures, especially controlling agriculture intensification in Chaohe River to decrease N pollution and decreasing water and soil loss and cage culture in Baihe River to weaken organic pollution.	Nitrogen	28-33	NBL1, DAN family BMP antagonist	Homo sapiens	24-27
26377835-6	2016	The human ASC groups (hASC and CTLA4Ig-hASC) showed a 13-week increase in average life spans and increased survival rates and decreased blood urea nitrogen, proteinuria, and glomerular IgG deposition.	Nitrogen	147-155	PYD and CARD domain containing	Homo sapiens	10-13
27048041-5	2016	The prealbumin, blood platelet, and blood urea nitrogen in the &lt;= 25 g/L ALB group were significantly lower than those in the &gt;= 30 g/L ALB group (p &lt; 0.05).	Nitrogen	47-55	albumin	Homo sapiens	76-79
27008783-9	2016	Although daily GPP was between 10- and 100-fold lower than daily respiration, photoautotrophic N uptake contributed to a 10% reduction in spring NO3- loads at the downstream site.	Nitrogen	95-96	NBL1, DAN family BMP antagonist	Homo sapiens	145-148
27313878-5	2016	Dietary n-3 polyunsaturated fatty acids (n-3 PUFAs) may exert a beneficial effect by shifting Th1/Th2 balance to a Th2 phenotype and increasing insulin sensitivity.	Nitrogen	8-9	insulin	Homo sapiens	144-151
28094746-6	2016	The results showed that PCM could significantly prolong the exhaustive swimming time of mice; decrease concentrations of serum lactic acid, urea nitrogen, creatine kinase, aspartate aminotransferase, alanine aminotransferase, and malondialdehyde; and increase liver and muscle glycogen contents and the concentrations of serum superoxide dismutase, glutathione per- oxidase, and catalase.	Nitrogen	145-153	solute carrier family 40 (iron-regulated transporter), member 1	Mus musculus	24-27
26567215-0	2016	The Ccl1-Kin28 kinase complex regulates autophagy under nitrogen starvation.	Nitrogen	56-64	C-C motif chemokine ligand 1	Homo sapiens	4-8
26308924-6	2016	The delta(15)N and delta(18)O values showed that NO3 (-) ions in the studied river samples were derived from precipitation, manure, sewage, soil organic nitrogen, and synthetic NO3 (-) fertilizer.	Nitrogen	153-161	NBL1, DAN family BMP antagonist	Homo sapiens	49-52
27220560-2	2016	Synthesis and Preliminary Pharmacological Investigation of Thiazole-Type Histamine H3-Receptor Antagonists with Lacking a Nitrogen Nucleus in the Side Chain.	Nitrogen	122-130	histamine H3 receptor	Cavia porcellus	73-94
26537798-7	2016	The altered N-glycosylation of TNF-alpha-treated adipocytes correlated with the regulation of specific glycosyltransferases, including the up-regulation of B4GalT5 and Ggta1 galactosyltransferases and down-regulation of ST3Gal6 sialyltransferase.	Nitrogen	12-13	tumor necrosis factor	Mus musculus	31-40
26537798-11	2016	This revealed the modulation of N-glycosylation on specific proteins in IR, including those previously associated with insulin-stimulated GLUT4 trafficking to the plasma membrane.	Nitrogen	32-33	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	138-143
26507394-9	2016	Milk urea nitrogen and plasma urea nitrogen (PUN) tended to respond quadratically (P = 0.06 and 0.10) when CSM replaced SBM to the diets.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
27178822-8	2016	2DG altered the N-glycosylation status of EGFR and induced the endoplasmic reticulum (ER) stress markers CHOP and BiP in vitro.	Nitrogen	16-17	epidermal growth factor receptor	Homo sapiens	42-46
26773776-9	2016	However, genotype effects on serum PON1 activity were not observed in women ingesting below the median (15:1) ratio of n-6/n-3 (P &gt; .05) but were observed in women ingesting above the ratio of n-6/n-3 (P &lt; .05).	Nitrogen	11-12	paraoxonase 1	Homo sapiens	35-39
26773776-9	2016	However, genotype effects on serum PON1 activity were not observed in women ingesting below the median (15:1) ratio of n-6/n-3 (P &gt; .05) but were observed in women ingesting above the ratio of n-6/n-3 (P &lt; .05).	Nitrogen	27-28	paraoxonase 1	Homo sapiens	35-39
27003064-5	2016	The anoxic second stage, optimized for anammox, was fed with the effluent from the nitritation reactor, reaching nitrogen removal rates above 0.20 g TN/L,d.	Nitrogen	113-121	tripartite motif containing 67	Homo sapiens	149-155
26483551-0	2015	Integrin alpha5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.	Nitrogen	136-137	epidermal growth factor receptor	Bos taurus	50-82
26161459-13	2016	CYP2C8 inhibitors reduced HLM N-demethylation by 47-75%, compared to 0-30% for CYP3A4 inhibitors.	Nitrogen	30-31	oxysterol binding protein 2	Homo sapiens	26-29
26526962-2	2015	The covalently bound B12 on the TiO2 surface transformed trichlorinated organic compounds into an ester and amide by UV light irradiation under mild conditions (in air at room temperature), while dichlorostilbenes (E and Z forms) were formed in nitrogen from benzotrichloride.	Nitrogen	245-253	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	21-24
26483551-9	2015	Taken together, these data are the first to demonstrate that EGFR activation can be regulated by the N-glycosylation of integrin alpha5, which is a novel molecular paradigm for the cross-talk between integrins and growth factor receptors.	Nitrogen	101-102	epidermal growth factor receptor	Bos taurus	61-65
26483551-4	2015	Here we show that integrin alpha5 functions as a negative regulator of epidermal growth factor receptor (EGFR) signaling through its N-glycosylation.	Nitrogen	133-134	epidermal growth factor receptor	Bos taurus	71-103
26549233-8	2015	Further analyses revealed that expression of two high-affinity nitrate transporter genes, NRT2.4 and NRT2.5, was down-regulated in cbl7 under nitrogen-starvation condition.	Nitrogen	142-150	nitrate transporter 2:1	Arabidopsis thaliana	90-94
26549233-8	2015	Further analyses revealed that expression of two high-affinity nitrate transporter genes, NRT2.4 and NRT2.5, was down-regulated in cbl7 under nitrogen-starvation condition.	Nitrogen	142-150	nitrate transporter 2:1	Arabidopsis thaliana	101-105
26549233-8	2015	Further analyses revealed that expression of two high-affinity nitrate transporter genes, NRT2.4 and NRT2.5, was down-regulated in cbl7 under nitrogen-starvation condition.	Nitrogen	142-150	calcineurin B-like protein 7	Arabidopsis thaliana	131-135
26483551-4	2015	Here we show that integrin alpha5 functions as a negative regulator of epidermal growth factor receptor (EGFR) signaling through its N-glycosylation.	Nitrogen	133-134	epidermal growth factor receptor	Bos taurus	105-109
26483551-6	2015	However, expression of the N-glycosylation mutant integrin alpha5, S3-5, which contains fewer N-glycans, reversed the suppression of the EGFR-mediated signaling and cell proliferation.	Nitrogen	27-28	epidermal growth factor receptor	Bos taurus	137-141
26423393-7	2015	Nematode Hsp70 were useful biosensors to monitor and assess the levels of nitrogen and phosphorus pollutions in wetlands.	Nitrogen	74-82	Heat Shock Protein	Caenorhabditis elegans	9-14
26318908-5	2015	The interaction between Thr201 and the side chain nitrogen of N-BP was shown to be important for tight binding inhibition by zoledronate (ZOL) and risedronate (RIS), although RIS was also still capable of interacting with the main-chain carbonyl of Lys200.	Nitrogen	50-58	Coenzyme A synthase	Homo sapiens	62-66
26567165-0	2015	Retraction note to: Isotopic analysis of N and O in NO3- by selective bacterial reduction to N2O for groundwater pollution.	Nitrogen	41-42	NBL1, DAN family BMP antagonist	Homo sapiens	52-55
26452604-5	2015	The N-glycosylation of TNFR1 could facilitate its capability of binding to TNFalpha and further promote the formation of TNFalpha autocrine loop in microglia stimulated by TNFalpha, resulting in excessive microglia activation and CNS inflammation.	Nitrogen	4-5	tumor necrosis factor	Homo sapiens	75-83
26385079-6	2015	We report that healthy humans consuming (15)N-labeled NO3(-) or NO2(-), with and without cLA supplementation, produce (15)NO2-cLA and corresponding metabolites that are detected in plasma and urine.	Nitrogen	44-45	NBL1, DAN family BMP antagonist	Homo sapiens	54-57
26452604-5	2015	The N-glycosylation of TNFR1 could facilitate its capability of binding to TNFalpha and further promote the formation of TNFalpha autocrine loop in microglia stimulated by TNFalpha, resulting in excessive microglia activation and CNS inflammation.	Nitrogen	4-5	tumor necrosis factor	Homo sapiens	121-129
26452604-5	2015	The N-glycosylation of TNFR1 could facilitate its capability of binding to TNFalpha and further promote the formation of TNFalpha autocrine loop in microglia stimulated by TNFalpha, resulting in excessive microglia activation and CNS inflammation.	Nitrogen	4-5	tumor necrosis factor	Homo sapiens	121-129
26458842-4	2015	The results showed that each of the human proteins, CELSR1, ST3GAL5 and VSIG10, lost an ancestrally conserved N-glycosylation site following human-chimpanzee divergence.	Nitrogen	110-111	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Homo sapiens	60-67
26231935-0	2015	Three N-Glycosylation Sites of Human Acetylcholinesterase Shares Similar Glycan Composition.	Nitrogen	6-7	acetylcholinesterase (Cartwright blood group)	Homo sapiens	37-57
26231935-1	2015	Acetylcholinesterase (AChE; EC 3.1.1.7) is a glycoprotein possessing three conserved N-linked glycosylation sites in mammalian species, locating at 296, 381, and 495 residues of the human sequence.	Nitrogen	85-86	acetylcholinesterase (Cartwright blood group)	Homo sapiens	0-20
26231935-1	2015	Acetylcholinesterase (AChE; EC 3.1.1.7) is a glycoprotein possessing three conserved N-linked glycosylation sites in mammalian species, locating at 296, 381, and 495 residues of the human sequence.	Nitrogen	85-86	acetylcholinesterase (Cartwright blood group)	Homo sapiens	22-26
26231935-2	2015	Several lines of evidence demonstrated that N-glycosylation of AChE affected the enzymatic activity, as well as its biosynthesis.	Nitrogen	44-45	acetylcholinesterase (Cartwright blood group)	Homo sapiens	63-67
26695920-7	2015	The levels of nitrogen com pounds (NO2 and NO3 ) were determined by the standard method using Hriss reagent.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	43-46
27844009-0	2015	The binding assessment with human serum albumin of novel six-coordinate Pt(IV) complexes, containing bidentate nitrogen donor/methyl ligands.	Nitrogen	111-119	albumin	Homo sapiens	34-47
26055207-3	2015	Diatoms possess a suite of N-related transporters and enzymes and utilize a variety of inorganic (e.g., nitrate, NO3(-); ammonium, NH4(+)) and organic (e.g., urea; amino acids) N sources for growth.	Nitrogen	27-28	NBL1, DAN family BMP antagonist	Homo sapiens	113-116
26233464-3	2015	Glutamine synthetase is also thought to be especially sensitive to inactivation by the oxygen- and nitrogen-centered radicals generated during strokes.	Nitrogen	99-107	glutamate-ammonia ligase	Homo sapiens	0-20
26605044-2	2015	In this nitrogen removal process, a complete biological denitrification from nitrate (NO3 (-)) to molecular nitrogen (N2) was achieved by four reduction steps, forming nitrite (NO2 (-)), nitric oxide (NO) and nitrous oxide (N2O) as intermediate compounds.	Nitrogen	8-16	NBL1, DAN family BMP antagonist	Homo sapiens	86-89
26525102-6	2015	In conclusion, total n-6 FA levels in plasma PL and plasma CRP levels are modulated by SNPs within PLA2G4A and PLA2G6 genes alone or in combination with fish oil supplementation.	Nitrogen	1-2	C-reactive protein	Homo sapiens	59-62
26094110-6	2015	The balance between N inputs (mineralization+deposition) and microbial immobilization and plant uptake defined the seasonal pattern of NO3 leaching.	Nitrogen	20-21	NBL1, DAN family BMP antagonist	Homo sapiens	135-138
26524472-3	2015	Here, we establish that, through N-acetylation of our original peptidomimetic series, we are able to improve DOR affinity and increase selectivity relative to KOR while maintaining the desired MOR agonist/DOR antagonist profile.	Nitrogen	33-34	opioid receptor, mu 1	Mus musculus	193-196
26605044-2	2015	In this nitrogen removal process, a complete biological denitrification from nitrate (NO3 (-)) to molecular nitrogen (N2) was achieved by four reduction steps, forming nitrite (NO2 (-)), nitric oxide (NO) and nitrous oxide (N2O) as intermediate compounds.	Nitrogen	108-116	NBL1, DAN family BMP antagonist	Homo sapiens	86-89
26605044-2	2015	In this nitrogen removal process, a complete biological denitrification from nitrate (NO3 (-)) to molecular nitrogen (N2) was achieved by four reduction steps, forming nitrite (NO2 (-)), nitric oxide (NO) and nitrous oxide (N2O) as intermediate compounds.	Nitrogen	118-120	NBL1, DAN family BMP antagonist	Homo sapiens	86-89
26610590-7	2015	Mutation of N-glycosylated Asn-146 to Asp in the N-terminal fragment Arg-32 to Glu-178 of ZP3 did not interrupt the interaction of this fragment with ZP4, but it did reduce the inhibitory activity of the complex for sperm-ZP binding.	Nitrogen	12-13	zona pellucida sperm-binding protein 3	Bos taurus	90-93
26554020-3	2015	Here the universality of QQS function in modulating carbon and nitrogen allocation is exemplified by a series of transgenic experiments.	Nitrogen	63-71	qua-quine starch	Arabidopsis thaliana	25-28
26554020-10	2015	These findings are, to our knowledge, the first insight into the mechanism of action of QQS in modulating carbon and nitrogen allocation across species.	Nitrogen	117-125	qua-quine starch	Arabidopsis thaliana	88-91
26554020-0	2015	QQS orphan gene regulates carbon and nitrogen partitioning across species via NF-YC interactions.	Nitrogen	37-45	qua-quine starch	Arabidopsis thaliana	0-3
26554020-2	2015	QQS (Qua-Quine Starch; At3g30720), an orphan gene unique to Arabidopsis thaliana, regulates metabolic processes affecting carbon and nitrogen partitioning among proteins and carbohydrates, modulating leaf and seed composition in Arabidopsis and soybean.	Nitrogen	133-141	qua-quine starch	Arabidopsis thaliana	0-3
26554020-2	2015	QQS (Qua-Quine Starch; At3g30720), an orphan gene unique to Arabidopsis thaliana, regulates metabolic processes affecting carbon and nitrogen partitioning among proteins and carbohydrates, modulating leaf and seed composition in Arabidopsis and soybean.	Nitrogen	133-141	qua-quine starch	Arabidopsis thaliana	5-21
26610590-7	2015	Mutation of N-glycosylated Asn-146 to Asp in the N-terminal fragment Arg-32 to Glu-178 of ZP3 did not interrupt the interaction of this fragment with ZP4, but it did reduce the inhibitory activity of the complex for sperm-ZP binding.	Nitrogen	12-13	zona pellucida glycoprotein 4	Bos taurus	150-153
26498681-2	2015	In this study, results showed that tunicamycin, an inhibitor of N-glycosylation, synergistically enhanced the antitumor activity of trastuzumab against HER2-overexpressing breast cancer cells through induction of cell cycle arrest and apoptosis.	Nitrogen	64-65	erb-b2 receptor tyrosine kinase 2	Homo sapiens	152-156
28955811-4	2016	Partial or non-glycosylated forms of a secreted form of hCES2 have been obtained by three approaches: (i) enzymatic deglycosylation with peptide N-glycosidase F; (ii) incubation with the inhibitor tunicamycin; ii) site directed mutagenesis of each or both N-glycosylation sites.	Nitrogen	145-146	carboxylesterase 2	Homo sapiens	56-61
28955811-7	2016	In agreement, mutation of each and both N-glycosylation sites led to decreased levels of secreted active hCES2.	Nitrogen	40-41	carboxylesterase 2	Homo sapiens	105-110
26403225-1	2015	Neutral 4-iodo-N-ethylimidazole 3 oxidatively adds to [Pt(PPh3)4] to give, in the presence of different tetraalkylammonium salts, complexes trans-[4], trans-[5], and trans-[6] containing an anionic C4-bound heterocycle with an unsubstituted ring-nitrogen atom.	Nitrogen	246-254	caveolin 1	Homo sapiens	58-62
26564056-9	2015	CD4(+)CD25(+) cell number was negatively associated with blood urea nitrogen (BUN), supernatant IL-4, serum IL-6, monoclonal immunoglobulin and beta2-microglobulin, as well as bone marrow plasma cell percentage and proteinuria; whereas positively associated with estimated glomerular filtration rate (eGFR) (all P &lt; 0.05).	Nitrogen	68-76	CD4 molecule	Homo sapiens	0-3
26297207-3	2015	In this study, we assessed the in vivo antitumor efficacy of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers conjugated to an E-selectin binding peptide (Esbp, DITWDQLWDLMK) and equipped with the chemotherapeutic drug doxorubicin (P-(Esbp)-DOX) or with the proapoptotic peptide D(KLAKLAK)2 (P-(Esbp)-KLAK).	Nitrogen	61-62	selectin, endothelial cell	Mus musculus	130-140
26276083-6	2015	Studies showed the involvement of CYP1A2, CYP2B6, CYP2C19, and CYP3A4 in N-dealkylation of all three compounds and additionally CYP2D6 for lefetamine and NEDPA.	Nitrogen	73-74	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	63-69
26159481-1	2015	A computational docking study of a series of de novo structural analogs of the highly potent, non-nitrogen containing, acetylcholinesterase inhibitor (+)-arisugacin A is presented.	Nitrogen	98-106	acetylcholinesterase (Cartwright blood group)	Homo sapiens	119-139
26364194-5	2015	Compounds like NH4Cl, NH4HCO3, NO3 (-), aniline, tri-nitrotoluene, cornsteep liquor, peptone, urea, and chitin are reported to have served as nitrogen source for SRB.	Nitrogen	142-150	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
26395994-7	2015	Changes at N-glycosylation motifs were also detected in IL-1, IL-10, IL-12B and IL-15.	Nitrogen	11-12	interleukin-12 subunit beta	Oryctolagus cuniculus	69-75
26154505-2	2015	In order to examine the impact of glycosyltransferase expression on the N-glycosylation of recombinant erythropoietin (rEPO), a human alpha2,6-sialyltransferase (ST6Gal1) was expressed in Chinese hamster ovary (CHO-K1) cells.	Nitrogen	72-73	erythropoietin	Homo sapiens	103-117
26104860-3	2015	Enantioselective CE with highly sulfated gamma-cyclodextrin as chiral selector was employed for analyzing in vitro (i) the kinetics of the N-demethylation of ketamine mediated by canine CYP3A12 and (ii) interactions occurring with racemic medetomidine and dexmedetomidine during coincubation with ketamine and canine liver microsomes (CLM), canine CYP3A12, human liver microsomes (HLM), and human CYP3A4.	Nitrogen	139-140	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	397-403
26206502-6	2015	Because the degradation of Glc3Man9GlcNAc2-PP-Dol is greatly inhibited in the presence of an N-glycosylation acceptor peptide that is recognized by the oligosaccharyltransferase (OST), the OST-mediated hydrolysis of DLO is the most likely mechanism responsible for the production of a large fraction of the cytosolic fOSs.	Nitrogen	38-39	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	152-177
26206502-6	2015	Because the degradation of Glc3Man9GlcNAc2-PP-Dol is greatly inhibited in the presence of an N-glycosylation acceptor peptide that is recognized by the oligosaccharyltransferase (OST), the OST-mediated hydrolysis of DLO is the most likely mechanism responsible for the production of a large fraction of the cytosolic fOSs.	Nitrogen	38-39	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	179-182
26206502-6	2015	Because the degradation of Glc3Man9GlcNAc2-PP-Dol is greatly inhibited in the presence of an N-glycosylation acceptor peptide that is recognized by the oligosaccharyltransferase (OST), the OST-mediated hydrolysis of DLO is the most likely mechanism responsible for the production of a large fraction of the cytosolic fOSs.	Nitrogen	38-39	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	189-192
26344643-1	2015	Density functional theory investigations reveal that the intramolecular additions of N-CN bonds to alkenes proceed in a novel asynchronous and concerted mechanism, while the intramolecular addition of O-CN bonds to alkenes may occur by both concerted and stepwise pathways.	Nitrogen	85-86	bone gamma-carboxyglutamate protein	Homo sapiens	201-205
26817293-4	2015	PDB is diagnosed on plain radiograph, the extent of disease is delineated by radionuclide bone imaging, the degree of activity is quantified biochemically, and it is treated with a nitrogen-containing bisphosphonate, most effectively by a single intravenous infusion of zoledronate 5mg.	Nitrogen	181-189	PDB1	Homo sapiens	0-3
26371408-6	2015	In the whole group protein N-linked Hcy correlated only with C-reactive protein (CRP; r = 0.44, p &lt; 0.0001).	Nitrogen	27-28	C-reactive protein	Homo sapiens	61-79
26371408-6	2015	In the whole group protein N-linked Hcy correlated only with C-reactive protein (CRP; r = 0.44, p &lt; 0.0001).	Nitrogen	27-28	C-reactive protein	Homo sapiens	81-84
26531304-0	2015	A theoretical investigation into the strength of N-NO2 bonds, ring strain and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX.	Nitrogen	177-185	membrane frizzled-related protein	Homo sapiens	49-54
26531304-0	2015	A theoretical investigation into the strength of N-NO2 bonds, ring strain and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX.	Nitrogen	177-185	membrane frizzled-related protein	Homo sapiens	213-218
26531304-1	2015	Changes in N-NO2 bond strength, ring strain energy and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX were investigated using DFT-B3LYP and MP2(full) methods with the 6-311++G(2df,2p) and aug-cc-pVTZ basis sets.	Nitrogen	154-162	membrane frizzled-related protein	Homo sapiens	11-16
26531304-1	2015	Changes in N-NO2 bond strength, ring strain energy and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX were investigated using DFT-B3LYP and MP2(full) methods with the 6-311++G(2df,2p) and aug-cc-pVTZ basis sets.	Nitrogen	154-162	membrane frizzled-related protein	Homo sapiens	190-195
26243812-0	2015	Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-alpha Antibody.	Nitrogen	15-23	tumor necrosis factor	Rattus norvegicus	78-105
26344782-1	2015	Dinitrogen complexes of the type Tp(R,R)Cr-N2-CrTp(R,R) are not the most labile precursors for Cr(i) chemistry, as they are sterically protected from obligatory associative ligand substitution.	Nitrogen	0-10	calreticulin	Homo sapiens	46-50
26362185-0	2015	Calreticulin discriminates the proximal region at the N-glycosylation site of Glc1Man9GlcNAc2 ligand.	Nitrogen	54-55	calreticulin	Homo sapiens	0-12
26362185-5	2015	Our results indicate that, similar to UGGT, CRT discriminates the proximal region at the N-glycosylation site, suggesting a similar mechanism mediating the recognition of aglycone moieties in the ER glycoprotein quality control system.	Nitrogen	89-90	calreticulin	Homo sapiens	44-47
26320580-1	2015	Mammals obtain nitrogen via the uptake of di- and tri-peptides in the gastrointestinal tract through the action of PepT1 and PepT2, which are members of the POT family of proton-coupled oligopeptide transporters.	Nitrogen	15-23	solute carrier family 15 member 1	Homo sapiens	115-120
26318452-1	2015	Ceramide synthases (CerS1-CerS6), which catalyze the N-acylation of the (dihydro)sphingosine backbone to produce (dihydro)ceramide in both the de novo and the salvage or recycling pathway of ceramide generation, have been implicated in the control of programmed cell death.	Nitrogen	53-54	ceramide synthase 1	Homo sapiens	20-25
26158348-1	2015	The oxides of nitrogen (chiefly NO, NO3(-), NO2(-) and N2O) are key components of the natural nitrogen cycle and are intermediates in a range of processes of enormous biological, environmental and industrial importance.	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	36-39
26158348-1	2015	The oxides of nitrogen (chiefly NO, NO3(-), NO2(-) and N2O) are key components of the natural nitrogen cycle and are intermediates in a range of processes of enormous biological, environmental and industrial importance.	Nitrogen	94-102	NBL1, DAN family BMP antagonist	Homo sapiens	36-39
26336134-0	2015	Histidine-rich glycoprotein function in hepatocellular carcinoma depends on its N-glycosylation status, and it regulates cell proliferation by inhibiting Erk1/2 phosphorylation.	Nitrogen	80-81	histidine-rich glycoprotein	Rattus norvegicus	0-27
26594576-1	2015	In the title mol-ecular salt, C12H24N(+) NO3 (-), the cyclohexyl rings adopt chair conformations with the exocyclic C-N bonds in equatorial orientations.	Nitrogen	36-37	NBL1, DAN family BMP antagonist	Homo sapiens	41-44
26594532-2	2015	The Co(II) ion has a slightly distorted octahedral coordination environment which is defined by two N atoms occupying the apical position, while the equatorial plane is furnished by two hy-droxy O atoms and two carboxyl-ate O atoms.	Nitrogen	100-101	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
26320580-1	2015	Mammals obtain nitrogen via the uptake of di- and tri-peptides in the gastrointestinal tract through the action of PepT1 and PepT2, which are members of the POT family of proton-coupled oligopeptide transporters.	Nitrogen	15-23	solute carrier family 15 member 2	Homo sapiens	125-130
26456786-9	2015	Using human CYPs, CYP1A2, CYP2C19, CYP2D6, and/or CYP3A4 were found to catalyze N-oxide formation and N-, O-demethylation and/or oxidation.	Nitrogen	80-81	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	35-41
26095306-5	2015	The detection limit of IgE is 7.6 fM (S/N = 3) with a linear range from 0.025 to 250 pM.	Nitrogen	40-41	immunoglobulin heavy constant epsilon	Homo sapiens	23-26
26085185-0	2015	In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.	Nitrogen	9-10	epidermal growth factor receptor	Homo sapiens	113-117
26085185-0	2015	In-depth N-glycome profiling of paired colorectal cancer and non-tumorigenic tissues reveals cancer-, stage- and EGFR-specific protein N-glycosylation.	Nitrogen	135-136	epidermal growth factor receptor	Homo sapiens	113-117
26085185-10	2015	Interestingly, a novel link between the EGFR status and the N-glycosylation was identified using hierarchical clustering of the N-glycome profiles.	Nitrogen	60-61	epidermal growth factor receptor	Homo sapiens	40-44
26085185-10	2015	Interestingly, a novel link between the EGFR status and the N-glycosylation was identified using hierarchical clustering of the N-glycome profiles.	Nitrogen	128-129	epidermal growth factor receptor	Homo sapiens	40-44
26277308-8	2015	Milk urea nitrogen concentration decreased linearly as the amount of SFSB in the diet increased.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
26456786-9	2015	Using human CYPs, CYP1A2, CYP2C19, CYP2D6, and/or CYP3A4 were found to catalyze N-oxide formation and N-, O-demethylation and/or oxidation.	Nitrogen	80-81	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	50-56
26207422-6	2015	Removal of N-glycosylation at residue 38 revealed an amino acid-dependent strong interaction with CALR likely preventing unloading of the misfolded protein from the ER chaperone down the normal secretory pathway.	Nitrogen	11-12	calreticulin	Homo sapiens	98-102
26061548-6	2015	Conditional ablation of TNF-alpha in macrophages significantly reduced albuminuria, the increase in plasma creatinine and blood urea nitrogen, histopathologic changes, and kidney macrophage recruitment compared to diabetic TNF-alpha(Flox/Flox) control mice after 12 weeks of streptozotocin-induced diabetes.	Nitrogen	133-141	tumor necrosis factor	Mus musculus	24-33
26207422-8	2015	This is mediated, however, through a novel mechanism of cloaking an N-glycosylation-independent strong interaction with the ER-resident CALR.	Nitrogen	68-69	calreticulin	Homo sapiens	136-140
26382581-0	2015	Differences in N-glycosylation of recombinant human coagulation factor VII derived from BHK, CHO, and HEK293 cells.	Nitrogen	15-16	coagulation factor VII	Homo sapiens	52-74
26008578-2	2015	Deletion of COQ9 results in dissociation of the CoQ-synthome, but over-expression of Coq8 putative kinase stabilizes the CoQ-synthome in the coq9 null mutant and leads to the accumulation of two nitrogen-containing Q intermediates, imino-demethoxy-Q6 (IDMQ6) and 3-hexaprenyl-4-aminophenol (4-AP) when para-aminobenzoic acid (pABA) is provided as a ring precursor.	Nitrogen	195-203	ubiquinone biosynthesis protein COQ9	Saccharomyces cerevisiae S288C	12-16
26213094-0	2015	Biphenyl-2,4,6,3",5"-pentacarboxylic acid as a tecton for six new Co(II) coordination polymers: pH and N-donor ligand-dependent assemblies, structure diversities and magnetic properties.	Nitrogen	103-104	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	66-72
26382684-5	2015	This pressure is much lower than that required for triple-to-single bond transformation in pure solid nitrogen (110 GPa).	Nitrogen	102-110	glycophorin A (MNS blood group)	Homo sapiens	116-119
26202462-2	2015	The yeast homologue, Sro7, is believed to act as a downstream effector of the Sec4 Rab GTPase to promote soluble N-ethylmaleimide-sensitive factor adaptor protein receptor (SNARE) assembly during Golgi-to-cell surface vesicle transport.	Nitrogen	113-114	Rab GTPase-binding protein SRO7	Saccharomyces cerevisiae S288C	21-25
26256403-13	2015	The N,N"-disubstituted or N"-substituted derivatives showed relatively low cytotoxicity but maintained the ability to inhibit IL-2 production.	Nitrogen	6-8	interleukin 2	Homo sapiens	126-130
25994654-2	2015	Throughout its lifespan, Izumo1 is posttranslationally modified, being both N-linked glycosylated on its extracellular domain and phosphorylated on the intracellular C-terminal tail.	Nitrogen	76-77	izumo sperm-egg fusion 1	Rattus norvegicus	25-31
26008578-2	2015	Deletion of COQ9 results in dissociation of the CoQ-synthome, but over-expression of Coq8 putative kinase stabilizes the CoQ-synthome in the coq9 null mutant and leads to the accumulation of two nitrogen-containing Q intermediates, imino-demethoxy-Q6 (IDMQ6) and 3-hexaprenyl-4-aminophenol (4-AP) when para-aminobenzoic acid (pABA) is provided as a ring precursor.	Nitrogen	195-203	ubiquinone biosynthesis protein COQ9	Saccharomyces cerevisiae S288C	141-145
26008578-6	2015	Deletion of COQ9 in the yeast coq5-5 mutant along with Coq8 over-expression and 13C6- pABA labeling leads to the absence of 13C6-DDMQ6, and the nitrogen-containing intermediates 13C6-4-AP and 13C6-IDDMQ6 persist.	Nitrogen	144-152	ubiquinone biosynthesis protein COQ9	Saccharomyces cerevisiae S288C	12-16
26008578-6	2015	Deletion of COQ9 in the yeast coq5-5 mutant along with Coq8 over-expression and 13C6- pABA labeling leads to the absence of 13C6-DDMQ6, and the nitrogen-containing intermediates 13C6-4-AP and 13C6-IDDMQ6 persist.	Nitrogen	144-152	2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase	Saccharomyces cerevisiae S288C	30-34
26008578-8	2015	The coq9-ts19 mutant had decreased Q6 content and increased levels of nitrogen-containing intermediates.	Nitrogen	70-78	ubiquinone biosynthesis protein COQ9	Saccharomyces cerevisiae S288C	4-8
26008578-9	2015	These findings identify Coq9 as a multi-functional protein that is required for the function of Coq6 and Coq7 hydroxylases, for removal of the nitrogen substituent from pABA-derived Q intermediates, and is an essential component of the CoQ synthome.	Nitrogen	143-151	ubiquinone biosynthesis protein COQ9	Saccharomyces cerevisiae S288C	24-28
26109616-11	2015	Using co-precipitated integrin alpha5beta1 followed by phytohaemagglutinin (PHA)-L and PHA-E blotting, we investigated whether GnT-V and GnT-III could modify the N-glycosylation profile in terms of the beta1,6-GlcNAc and bis-GlcNAc structures in integrin alpha5beta1 during the first trimester in both groups.	Nitrogen	162-163	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	127-132
26617699-7	2015	In addition, the regulated expression of GnT-V in the CNE-2R cells converted the heterogeneous N-glycosylated forms of CD147.	Nitrogen	55-56	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	41-46
26356136-3	2015	In this study, PTH(1-34) was conjugated with non-radioactive (stable F isotope) N-succinimidyl 4-fluorobenzoate (SFB) leading to three isomeric mono-fluorobenzoated (FBz) PTH followed by Liquid chromatography-Tandem mass spectrometry (LC-MS/MS) assisted structural identification.	Nitrogen	80-81	parathyroid hormone	Homo sapiens	171-174
26356136-3	2015	In this study, PTH(1-34) was conjugated with non-radioactive (stable F isotope) N-succinimidyl 4-fluorobenzoate (SFB) leading to three isomeric mono-fluorobenzoated (FBz) PTH followed by Liquid chromatography-Tandem mass spectrometry (LC-MS/MS) assisted structural identification.	Nitrogen	80-81	parathyroid hormone	Homo sapiens	15-18
26278010-8	2015	The presented work clearly shows that PEDOT: PSS forms a hybrid heterojunction with n-Si behaving similar to a conventional pn-junction and not, like commonly assumed, a Schottky junction.	Nitrogen	9-10	PSS	Homo sapiens	45-48
26270954-3	2015	To date, most of the ligands targeting 5-HT2B have been nitrogen-containing compounds.	Nitrogen	56-64	5-hydroxytryptamine receptor 2B	Homo sapiens	39-45
26130766-1	2015	Lyso-glycosphingolipids (lyso-GSLs), the N-deacylated forms of glycosphingolipids (GSLs), are important synthetic intermediates for the preparation of GSL analogs.	Nitrogen	41-42	cathepsin A	Homo sapiens	30-33
26379630-8	2015	Gene expression study of CrPGP1 and CrPGP2 in nutrient-starved C. reinhardtii showed differential response to phosphorus and nitrogen deficiency.	Nitrogen	125-133	uncharacterized protein	Chlamydomonas reinhardtii	25-31
26379630-8	2015	Gene expression study of CrPGP1 and CrPGP2 in nutrient-starved C. reinhardtii showed differential response to phosphorus and nitrogen deficiency.	Nitrogen	125-133	uncharacterized protein	Chlamydomonas reinhardtii	36-42
26089125-2	2015	As a result of the porous internal structure in the solid state, cage 1 exhibited a good CO2 uptake capacity of 12.5 wt% and a high selectivity for CO2 over N2 adsorption of 80 (273 K, 1 bar) with a BET surface area of 432 m(2) g(-1).	Nitrogen	157-159	cancer antigen 1	Homo sapiens	65-71
26177091-3	2015	Homologation to the corresponding diene analogues yielded a mixture of Z,E and E,E isomers; substitution of the indoline nitrogen with an N-benzyl group resulted in increased binding to alpha-syn and reasonable selectivity for alpha-syn versus Abeta and tau.	Nitrogen	121-129	amyloid beta precursor protein	Homo sapiens	244-249
26179746-2	2015	N-protected 1-aminopyridinium salts are the key compounds and serve as amidyl radical precursors by the action of Ir photocatalysts, fac-[Ir(ppy)3] and [Ir(ppy)2 (dtbbpy)](PF6) (ppy=2-pyridylphenyl, dtbbpy=4,4"-di-tert-butyl-2,2"-bipyridine).	Nitrogen	0-1	FA complementation group C	Homo sapiens	133-136
26108188-4	2015	We detected a positive O-GlcNAcylation signal in the immunoprecipitated EGFR by Western blotting using two distinct specific anti-O-GlcNAc antibodies even after N-deglycosylation of the receptor using peptide-N-glycosidase F (PNGase F).	Nitrogen	28-29	epidermal growth factor receptor	Homo sapiens	72-76
26172528-4	2015	Compound 3 is not kinetically stable, because, under thermodynamic control, it leads to 4, in which the PPh3 is trans to a N atom of the Phen ligand.	Nitrogen	123-124	caveolin 1	Homo sapiens	104-108
25969370-13	2015	CONCLUSION: In this series, patients who received NAC/N-CRT for cT3 and/or cN+ PUC appeared to demonstrate improved survival compared with those who underwent upfront surgery with or without ACH.	Nitrogen	2-3	cancer antigen 1	Homo sapiens	64-67
25725335-7	2015	N2 increased cell viability, ameliorated neuron cell injury by decreasing LDH activity, and inhibited cell apoptotic rate while suppressed apoptotic signaling via inhibiting the bax expression, and elevating the bcl-2 expression.	Nitrogen	0-2	BCL2, apoptosis regulator	Rattus norvegicus	212-217
26592006-4	2015	The percentages of various N species showed that NO3- -N was the major N species in the Yangtze River and Wangyu River during the 2 water transfer processes.	Nitrogen	27-28	NBL1, DAN family BMP antagonist	Homo sapiens	49-52
25876792-3	2015	Proteolysis was primarily affected by curd cooking temperature because chymosin-mediated hydrolysis of alphas1 casein was slower in cheeses treated at 56  C. Additionally, the nitrogen content in the cheese soluble fractions was consistently lower in the cheeses scalded at 56  C than those cooked at 50  C. A significant influence of the type of coagulant enzyme was observed, especially in the nitrogen fractions and peptide profiles, which demonstrated that camel chymosin was slightly less proteolytic; however, these differences were lower than those caused by the scalding temperature.	Nitrogen	176-184	chymosin	Camelus bactrianus	71-79
25876792-3	2015	Proteolysis was primarily affected by curd cooking temperature because chymosin-mediated hydrolysis of alphas1 casein was slower in cheeses treated at 56  C. Additionally, the nitrogen content in the cheese soluble fractions was consistently lower in the cheeses scalded at 56  C than those cooked at 50  C. A significant influence of the type of coagulant enzyme was observed, especially in the nitrogen fractions and peptide profiles, which demonstrated that camel chymosin was slightly less proteolytic; however, these differences were lower than those caused by the scalding temperature.	Nitrogen	396-404	chymosin	Camelus bactrianus	71-79
25947573-12	2015	Among these patients, the HER-2-positive group demonstrated both higher T/N ratios and a greater change in T/N ratio than patients with other breast cancer subtypes (P &lt; 0.05).	Nitrogen	74-75	erb-b2 receptor tyrosine kinase 2	Homo sapiens	26-31
25947573-12	2015	Among these patients, the HER-2-positive group demonstrated both higher T/N ratios and a greater change in T/N ratio than patients with other breast cancer subtypes (P &lt; 0.05).	Nitrogen	109-110	erb-b2 receptor tyrosine kinase 2	Homo sapiens	26-31
25947573-13	2015	A strong correlation was found between changes in T/N ratio and pathological tumor response in the HER-2-positive group (P &lt; 0.03).	Nitrogen	52-53	erb-b2 receptor tyrosine kinase 2	Homo sapiens	99-104
26041282-6	2015	Interestingly, the I399T mutation introduces an N-glycosylation site within HVR1 and increases the density of virions and their sensitivity to neutralization with anti-apolipoprotein E (anti-ApoE) antibodies, suggesting that this mutation likely induces conformational changes in HVR1 that in turn modulate the association with ApoE.	Nitrogen	48-49	apolipoprotein E	Homo sapiens	168-184
26041282-6	2015	Interestingly, the I399T mutation introduces an N-glycosylation site within HVR1 and increases the density of virions and their sensitivity to neutralization with anti-apolipoprotein E (anti-ApoE) antibodies, suggesting that this mutation likely induces conformational changes in HVR1 that in turn modulate the association with ApoE.	Nitrogen	48-49	apolipoprotein E	Homo sapiens	191-195
26041282-6	2015	Interestingly, the I399T mutation introduces an N-glycosylation site within HVR1 and increases the density of virions and their sensitivity to neutralization with anti-apolipoprotein E (anti-ApoE) antibodies, suggesting that this mutation likely induces conformational changes in HVR1 that in turn modulate the association with ApoE.	Nitrogen	48-49	apolipoprotein E	Homo sapiens	328-332
25725335-8	2015	Furthermore, the neuroprotective effect of N2 was associated with the PI3K/Akt pathway which was proved by the use of PI3K inhibitor LY294002.	Nitrogen	43-45	AKT serine/threonine kinase 1	Rattus norvegicus	75-78
26120972-6	2015	Fabricated PAF-56P/PSF membranes were further exploited for CO2 capture, which was exemplified by gas separations of CO2/N2 mixtures.	Nitrogen	121-123	splicing factor proline and glutamine rich	Homo sapiens	11-22
26218428-5	2015	Sequence analysis of zebrafish ca10a and ca10b reveals strongly predicted signal peptides, N-glycosylation sites, and a potential disulfide, all of which are conserved, suggesting that all of CARP X and XI are secretory proteins and potentially dimeric.	Nitrogen	91-92	carbonic anhydrase Xb	Danio rerio	41-46
25998389-8	2015	From these experiments, we concluded that each of these three genes were involved in N-linked sialylation and ST3GAL4 may play the critical role in glycoprotein sialylation of recombinant proteins such as EPO.	Nitrogen	85-86	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4	Cricetulus griseus	110-117
26345802-2	2015	Glutamine synthetase (GS), which is a major participant in nitrogen metabolism, can convert inorganic nitrogen into organic nitrogen.	Nitrogen	59-67	glutamate-ammonia ligase	Homo sapiens	0-20
26345802-2	2015	Glutamine synthetase (GS), which is a major participant in nitrogen metabolism, can convert inorganic nitrogen into organic nitrogen.	Nitrogen	102-110	glutamate-ammonia ligase	Homo sapiens	0-20
26345802-2	2015	Glutamine synthetase (GS), which is a major participant in nitrogen metabolism, can convert inorganic nitrogen into organic nitrogen.	Nitrogen	102-110	glutamate-ammonia ligase	Homo sapiens	0-20
26045554-0	2015	Two N-glycosylation Sites in the GluN1 Subunit Are Essential for Releasing N-methyl-d-aspartate (NMDA) Receptors from the Endoplasmic Reticulum.	Nitrogen	4-5	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	33-38
26045554-4	2015	Using biochemistry, confocal and electron microscopy, and electrophysiology in conjunction with a lentivirus-based molecular replacement strategy, we found that NMDARs are released from the ER only when two asparagine residues in the GluN1 subunit (Asn-203 and Asn-368) are N-glycosylated.	Nitrogen	161-162	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	234-239
26120972-7	2015	The PAF-56P/PSF membranes show a high selectivity of CO2 over N2 with a separation factor of 38.9 due to the abundant nitrogen groups in the PAF-56P framework.	Nitrogen	62-64	splicing factor proline and glutamine rich	Homo sapiens	12-15
26120972-7	2015	The PAF-56P/PSF membranes show a high selectivity of CO2 over N2 with a separation factor of 38.9 due to the abundant nitrogen groups in the PAF-56P framework.	Nitrogen	118-126	splicing factor proline and glutamine rich	Homo sapiens	12-15
26172854-6	2015	We show that, under poor nitrogen supply, the TORC1 effector kinase" Npr1" promotes phosphorylation of Amu1/Par32 which appears mainly cytosolic while ammonium transport proteins are active.	Nitrogen	25-33	natriuretic peptide receptor 1	Homo sapiens	69-73
26172854-7	2015	Upon preferred nitrogen supplementation, like glutamine or ammonium addition, TORC1 upregulation enables Npr1 inhibition and Amu1/Par32 dephosphorylation.	Nitrogen	15-23	natriuretic peptide receptor 1	Homo sapiens	105-109
25960298-0	2015	N-Glycosylation modulates filopodia-like protrusions induced by sez-6 through regulating the distribution of this protein on the cell surface.	Nitrogen	0-1	seizure related gene 6	Mus musculus	64-69
33434968-5	2015	The in vitro and in vivo anti-inflammatory evaluation was performed and it has been confirmed that these nitrogen-rich surfaces could inhibit the activation of macrophages by down-regulation of the pro-inflammatory cytokines TNF-alpha and IL-6, and exhibit acceptable tissue-compatibility.	Nitrogen	105-113	tumor necrosis factor	Homo sapiens	225-234
33434968-5	2015	The in vitro and in vivo anti-inflammatory evaluation was performed and it has been confirmed that these nitrogen-rich surfaces could inhibit the activation of macrophages by down-regulation of the pro-inflammatory cytokines TNF-alpha and IL-6, and exhibit acceptable tissue-compatibility.	Nitrogen	105-113	interleukin 6	Homo sapiens	239-243
25960298-4	2015	Here, we studied the role of N-glycosylation in sez-6 function.	Nitrogen	29-30	seizure related gene 6	Mus musculus	48-53
25960298-12	2015	Our results indicate that N-glycosylation regulates cell morphology through modulating the cell surface distribution of sez-6 protein.	Nitrogen	26-27	seizure related gene 6	Mus musculus	120-125
26152587-4	2015	We show that under nitrogen-rich conditions, TORC1 positively regulates the phosphorylation and cytoplasmic retention of Gaf1 via the PP2A-like phosphatase Ppe1.	Nitrogen	19-27	carboxylesterase-mitochondrial 37S ribosomal protein YmS2	Saccharomyces cerevisiae S288C	156-160
26100877-0	2015	N-linked glycosylation of protease-activated receptor-1 at extracellular loop 2 regulates G-protein signaling bias.	Nitrogen	0-1	coagulation factor II thrombin receptor	Homo sapiens	26-55
26100877-4	2015	Here, we report that N-linked glycosylation of PAR1 at extracellular loop 2 (ECL2) controls G12/13 versus Gq coupling specificity in response to thrombin stimulation.	Nitrogen	21-22	coagulation factor II thrombin receptor	Homo sapiens	47-51
26100877-4	2015	Here, we report that N-linked glycosylation of PAR1 at extracellular loop 2 (ECL2) controls G12/13 versus Gq coupling specificity in response to thrombin stimulation.	Nitrogen	21-22	coagulation factor II, thrombin	Homo sapiens	145-153
26100877-11	2015	These studies suggest that N-linked glycosylation at ECL2 contributes to the stabilization of an active PAR1 state that preferentially couples to G12/13 versus Gq and defines a previously unidentified function for N-linked glycosylation of GPCRs in regulating G-protein signaling bias.	Nitrogen	27-28	coagulation factor II thrombin receptor	Homo sapiens	104-108
26100877-11	2015	These studies suggest that N-linked glycosylation at ECL2 contributes to the stabilization of an active PAR1 state that preferentially couples to G12/13 versus Gq and defines a previously unidentified function for N-linked glycosylation of GPCRs in regulating G-protein signaling bias.	Nitrogen	214-215	coagulation factor II thrombin receptor	Homo sapiens	104-108
25919894-5	2015	The binding site of PIM was identified by chemical-shift perturbation experiments with uniformly (15)N-labeled ZG16p.	Nitrogen	100-102	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	20-23
25919894-5	2015	The binding site of PIM was identified by chemical-shift perturbation experiments with uniformly (15)N-labeled ZG16p.	Nitrogen	100-102	zymogen granule protein 16	Homo sapiens	111-116
26152587-13	2015	Under nitrogen-rich conditions, TORC1 positively regulates the phosphorylation and cytoplasmic retention of Gaf1 via the PP2A-like phosphatase Ppe1.	Nitrogen	6-14	carboxylesterase-mitochondrial 37S ribosomal protein YmS2	Saccharomyces cerevisiae S288C	143-147
29218193-1	2015	We report on the successful synthesis and hyperpolarization of N-unprotected alpha-amino acid ethyl propionate esters and extensively, on an alanine derivative hyperpolarized by PHIP (4.4 +- 1.0% 13C-polarization), meeting required levels for in vivo detection.	Nitrogen	63-64	pleckstrin homology domain interacting protein	Homo sapiens	178-182
25979810-4	2015	The direct comparison with other selective Vgamma9 T cell agonists including phosphoantigens and nitrogen-containing bisphosphonates revealed the superiority of the [(Her2)2 x Vgamma9] tribody in triggering gammadelta T cell-mediated tumor cell killing with negligible induction of gammadelta T cell death.	Nitrogen	97-105	erb-b2 receptor tyrosine kinase 2	Homo sapiens	167-171
25867209-2	2015	The aim of this study was to demonstrate that nitrogen balance (NB) in cardiac patients admitted to the intensive care unit (ICU) is related to their insulin sensitivity level and that supraphysiologic doses of insulin can restore anabolism.	Nitrogen	46-54	insulin	Homo sapiens	150-157
25867209-2	2015	The aim of this study was to demonstrate that nitrogen balance (NB) in cardiac patients admitted to the intensive care unit (ICU) is related to their insulin sensitivity level and that supraphysiologic doses of insulin can restore anabolism.	Nitrogen	46-54	insulin	Homo sapiens	211-218
26071720-3	2015	However, for itraconazole, the additional transition to the nematic phase was observed and characterized by the pressure coefficient dT(n)/dp = 258 K/GPa.	Nitrogen	136-138	glycophorin A (MNS blood group)	Homo sapiens	150-153
25396696-1	2015	OBJECTIVE: To investigate the hepatoprotective potential of n-butanolic extract of Astragalus monspessulanus L. (EAM) against in-vitro/in-vivo carbon tetrachloride (CCl4)-induced liver damage in rats.	Nitrogen	15-16	C-C motif chemokine ligand 4	Rattus norvegicus	165-169
25871637-0	2015	The IRC7 gene encodes cysteine desulphydrase activity and confers on yeast the ability to grow on cysteine as a nitrogen source.	Nitrogen	112-120	cysteine-S-conjugate beta-lyase IRC7	Saccharomyces cerevisiae S288C	4-8
25871637-5	2015	We further show that, in vivo, the IRC7 gene is both necessary and sufficient for yeast to grow on l-cysteine as a nitrogen source, and that overexpression of the gene results in increased H2 S production.	Nitrogen	115-123	cysteine-S-conjugate beta-lyase IRC7	Saccharomyces cerevisiae S288C	35-39
26040717-8	2015	Atg39-dependent autophagy of the perinuclear ER/nucleus is required for cell survival under nitrogen-deprivation conditions.	Nitrogen	92-100	Atg39p	Saccharomyces cerevisiae S288C	0-5
26018983-5	2015	The last step is a proton transfer from Thr1-N(z) to another olefin carbon of SylA to complete the inhibition reaction process.	Nitrogen	45-46	thyroid hormone receptor beta	Homo sapiens	40-44
26150813-3	2015	We also found that in these culture conditions, nitrogen levels fixed by Trichodesmium were higher in treatments with insufficient B12 than in treatments with higher B12 availability.	Nitrogen	48-56	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	131-134
26150813-3	2015	We also found that in these culture conditions, nitrogen levels fixed by Trichodesmium were higher in treatments with insufficient B12 than in treatments with higher B12 availability.	Nitrogen	48-56	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	166-169
26150813-7	2015	These results show that the interlocking availabilities of Co and B12 may influence the growth and nitrogen fixation of Trichodesmium in the ocean.	Nitrogen	99-107	NADH:ubiquinone oxidoreductase subunit B3	Homo sapiens	66-69
25864004-5	2015	Maximum conversion of ammonia to nitrogen at the rates of 0.569 and 0.766 mg L(-1) min(-1) are achieved at low (0.01 M NH4Cl and 0.1 M KOH) and high (0.07 M NH4Cl and 0.15 M KOH) inlet concentrations, respectively.	Nitrogen	33-41	immunoglobulin kappa variable 1-16	Homo sapiens	77-89
26575549-7	2015	This change in the spin coupling of the electrons in the bonding orbitals down the periodic table may contribute to the rather dramatic decrease in the strengths of the Pn2 bonds from N2 to As2 as well as in the increase in their chemical reactivity and should be taken into account in more detailed analyses of the bond energies in these species.	Nitrogen	184-186	amyloid beta precursor protein	Homo sapiens	169-172
26010715-1	2015	Generated in situ from air-stable cobalt precursors or readily synthesized using NaHBEt3, (PPh3)3CoH(N2) was found to be an effective catalyst for the hydroboration of alkenes.	Nitrogen	101-103	caveolin 1	Homo sapiens	91-95
25639738-0	2015	Combination of IgG N-glycomics and corresponding transcriptomics data to identify anti-TNF-alpha treatment responders in inflammatory diseases.	Nitrogen	19-20	tumor necrosis factor	Homo sapiens	87-96
26139944-3	2015	In addition to generating the environmentally benign N2 as the only byproduct, this Co(II)-based metalloradical aziridination process features mild reaction conditions and operational simplicity.	Nitrogen	53-55	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	84-89
26081279-3	2015	Although dug2 showed constitutive transcription, dug1 and dug3 were induced by carbon and nitrogen starvation and yeast extract did not caused significant changes in their relative transcription.	Nitrogen	90-98	metallodipeptidase	Saccharomyces cerevisiae S288C	49-53
26081279-3	2015	Although dug2 showed constitutive transcription, dug1 and dug3 were induced by carbon and nitrogen starvation and yeast extract did not caused significant changes in their relative transcription.	Nitrogen	90-98	glutamine amidotransferase subunit DUG3	Saccharomyces cerevisiae S288C	58-62
25691235-6	2015	Milk fatty acid composition was associated primarily with estrous-cycle day: polyunsaturated fatty acids increased by 16%, n-6 by 15% and n-3 by 1% from day 1 to 8 post-estrus.	Nitrogen	26-27	Weaning weight-maternal milk	Bos taurus	0-4
25691235-6	2015	Milk fatty acid composition was associated primarily with estrous-cycle day: polyunsaturated fatty acids increased by 16%, n-6 by 15% and n-3 by 1% from day 1 to 8 post-estrus.	Nitrogen	82-83	Weaning weight-maternal milk	Bos taurus	0-4
25382218-7	2015	The new approach was thoroughly validated for the CYP3A4-mediated N-demethylation pathway of ketamine and applied to the determination of its kinetic parameters and the inhibition characteristics in presence of ketoconazole and dexmedetomidine.	Nitrogen	66-67	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	50-56
25690651-0	2015	The atypical N-glycosylation motif, Asn-Cys-Cys, in human GPR109A is required for normal cell surface expression and intracellular signaling.	Nitrogen	13-14	hydroxycarboxylic acid receptor 2	Homo sapiens	58-65
25690651-3	2015	We found that human GPR109A (hGPR109A) has an N-glycosylation site at Asn(17) in the N-terminal atypical motif, Asn(17)-Cys(18)-Cys(19).	Nitrogen	46-47	hydroxycarboxylic acid receptor 2	Homo sapiens	20-27
25690651-3	2015	We found that human GPR109A (hGPR109A) has an N-glycosylation site at Asn(17) in the N-terminal atypical motif, Asn(17)-Cys(18)-Cys(19).	Nitrogen	46-47	hydroxycarboxylic acid receptor 2	Homo sapiens	29-37
25690651-6	2015	First, Asn(17)-X-Cys(19) contributed to hGPR109A N-glycosylation by acting as an atypical motif.	Nitrogen	49-50	hydroxycarboxylic acid receptor 2	Homo sapiens	40-48
25690651-7	2015	This modification is required for the normal surface expression of hGPR109A, as evidenced by the reduced surface expression of the nonglycosylated mutants, hGPR109A/N17A, and the finding that hGPR109A/C19S and hGPR109A/C19T, which are N-glycosylated at Asn(17), exhibited expression similar to the wild-type receptor.	Nitrogen	165-166	hydroxycarboxylic acid receptor 2	Homo sapiens	67-75
25862938-0	2015	Neuroprotective role of an N-acetyl serotonin derivative via activation of tropomyosin-related kinase receptor B after subarachnoid hemorrhage in a rat model.	Nitrogen	0-1	neurotrophic receptor tyrosine kinase 2	Rattus norvegicus	75-112
26387330-3	2015	The results showed, in the enrichment phase 4, under the load of TN 330 mg x L(-1), the best nitrogen removal effect was obtained, which the TN and NO3- -N removal rates reached 90.9% and 100% within 9 hours, respectively.	Nitrogen	93-101	NBL1, DAN family BMP antagonist	Homo sapiens	148-151
25974366-4	2015	Results showed that As(V) caused decreases in growth, photosynthesis (measured as chlorophyll fluorescence) and nitrogen content, which was accompanied by the accumulation of As.	Nitrogen	112-120	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	20-25
25627085-7	2015	Interaction between TM4SF5 and CD44 was through their extracellular domains with N-glycosylation modifications.	Nitrogen	81-82	transmembrane 4 superfamily member 5	Mus musculus	20-26
25851723-1	2015	Recently autosomal recessively inherited mutations in the gene encoding Jagunal homolog 1 (JAGN1) was described as a novel disease-causing gene of severe congenital neutropenia (SCN) JAGN1-mutant neutrophils were characterized by abnormality in endoplasmic reticulum structure, absence of granules, abnormal N-glycosylation of proteins and susceptibility to apoptosis.	Nitrogen	94-95	jagunal homolog 1	Homo sapiens	72-89
25933946-3	2015	RESULTS: Administration of CCl4 significantly (p&lt;0.001) increased the levels of renal function test such as creatinine and blood urea nitrogen (BUN).	Nitrogen	137-145	C-C motif chemokine ligand 4	Rattus norvegicus	27-31
26011424-5	2015	In contrast with our hypothesis, EPO down regulated plasma BDNF levels in patients with TRD (mean reduction at week 9 (95% CI): EPO 10.94 ng/l (4.51-21.41 ng/l); mean increase at week 9: Saline 0.52 ng/l, p=0.04 (-5.88-4.48 ng/l) p=0.04, partial n2=0.12).	Nitrogen	246-248	erythropoietin	Homo sapiens	33-36
25985465-6	2015	As a result, the N-doped 2D wavelike LTO with 0.6 wt.% of "carbon joint" not only exhibits exciting capacity of ~180 and ~150 mA h g(-1) for fast lithium storage at high discharge/charge rates of 1.7 and 8.5 A g(-1) (10C and 50C) respectively, but also shows excellent low-temperature performance at -20 C. In addition, the cost may be further decreased due to recycled functional reagents.	Nitrogen	17-18	Rho GTPase activating protein 9	Homo sapiens	217-220
26093727-9	2015	Serum Fetuin-A levels were positively correlated with blood urea nitrogen level (r = .241, P = .025) and serum creatinine level (r = .262, P = .014), whereas it was negatively correlated with serum phosphorus level (r = -.409, P &lt; .001).	Nitrogen	65-73	alpha 2-HS glycoprotein	Homo sapiens	6-14
26925376-2	2015	The aim of this study was to assess the influence of a low calorie diet with or without n-3 PUFA supplementation on glucose dependent insulinotropic polypeptide (GIP) output and insulin sensitivity markers in obese subjects.	Nitrogen	41-42	gastric inhibitory polypeptide	Homo sapiens	116-160
26925376-2	2015	The aim of this study was to assess the influence of a low calorie diet with or without n-3 PUFA supplementation on glucose dependent insulinotropic polypeptide (GIP) output and insulin sensitivity markers in obese subjects.	Nitrogen	41-42	gastric inhibitory polypeptide	Homo sapiens	162-165
26925376-2	2015	The aim of this study was to assess the influence of a low calorie diet with or without n-3 PUFA supplementation on glucose dependent insulinotropic polypeptide (GIP) output and insulin sensitivity markers in obese subjects.	Nitrogen	41-42	insulin	Homo sapiens	134-141
25771539-1	2015	The protein N-terminal methyltransferase 1 (NTMT1) catalyzes the transfer of the methyl group from the S-adenosyl-l-methionine to the protein alpha-amine, resulting in formation of S-adenosyl-l-homocysteine and alpha-N-methylated proteins.	Nitrogen	12-13	N-terminal Xaa-Pro-Lys N-methyltransferase 1	Homo sapiens	44-49
25851723-1	2015	Recently autosomal recessively inherited mutations in the gene encoding Jagunal homolog 1 (JAGN1) was described as a novel disease-causing gene of severe congenital neutropenia (SCN) JAGN1-mutant neutrophils were characterized by abnormality in endoplasmic reticulum structure, absence of granules, abnormal N-glycosylation of proteins and susceptibility to apoptosis.	Nitrogen	94-95	jagunal homolog 1	Homo sapiens	183-188
25911228-1	2015	The trimethylguanosine (TMG) caps of small nuclear (sn) RNAs are synthesized by the enzyme Tgs1 via sequential methyl additions to the N2 atom of the m(7)G cap.	Nitrogen	135-137	RNA methyltransferase	Saccharomyces cerevisiae S288C	91-95
25944100-5	2015	atg12 plants have compromised autophagic transport as determined by localization of a YFP-ATG8 reporter and its vacuolar cleavage during nitrogen or fixed-carbon starvation.	Nitrogen	137-145	Ubiquitin-like protein ATG12	Zea mays	0-5
25944100-8	2015	Nitrogen partitioning studies revealed that remobilization is impaired in atg12 plants, which significantly decreases seed yield and nitrogen-harvest index.	Nitrogen	0-8	Ubiquitin-like protein ATG12	Zea mays	74-79
25944100-8	2015	Nitrogen partitioning studies revealed that remobilization is impaired in atg12 plants, which significantly decreases seed yield and nitrogen-harvest index.	Nitrogen	133-141	Ubiquitin-like protein ATG12	Zea mays	74-79
25621833-7	2015	Treatment of swine wastewater with zeolite Na-P1 resulted in a high removal capacity for total ammoniacal nitrogen (31mgg(-1)).	Nitrogen	106-114	Nucleosome assembly protein 1	Drosophila melanogaster	43-48
25898205-9	2015	Hence, the EPO-EPOR binding site in X. laevis locates the distal region of artificially introduced three N-glycosylation sites, demonstrating that the vital conformation to exert biological activity is conserved between humans and X. laevis, despite the low similarity in primary structures of EPO and EPOR.	Nitrogen	105-106	erythropoietin	Homo sapiens	11-14
25909858-6	2015	In S. cerevisiae, Gap1 activity is regulated by shuttling between the plasma membrane (nitrogen limiting conditions) and the vacuole (nitrogen sufficiency), which we also show for FfGap1.	Nitrogen	87-95	amino acid permease GAP1	Saccharomyces cerevisiae S288C	18-22
25909858-6	2015	In S. cerevisiae, Gap1 activity is regulated by shuttling between the plasma membrane (nitrogen limiting conditions) and the vacuole (nitrogen sufficiency), which we also show for FfGap1.	Nitrogen	134-142	amino acid permease GAP1	Saccharomyces cerevisiae S288C	18-22
25651456-1	2015	In humans, the metabolic bioactivation of pyrrolizidine alkaloids (PAs) is mediated mainly by cytochrome P450 3A4 (CYP3A4) via the hydroxylation of their necine bases at C3 or C8 of heliotridine- and retronecine-type PAs or at the N atom of the methyl substituent of otonecine-type PAs.	Nitrogen	231-232	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	94-113
25651456-1	2015	In humans, the metabolic bioactivation of pyrrolizidine alkaloids (PAs) is mediated mainly by cytochrome P450 3A4 (CYP3A4) via the hydroxylation of their necine bases at C3 or C8 of heliotridine- and retronecine-type PAs or at the N atom of the methyl substituent of otonecine-type PAs.	Nitrogen	231-232	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	115-121
25781479-3	2015	We have carried out electron microscopy, X-ray diffraction, nitrogen sorption, electrophoresis, thermogravimetric analysis, and confocal microscopy to confirm that the ~10 nm catalase molecules are embedded in 2 mum single-crystalline ZIF-90 crystals with ~5 wt % loading.	Nitrogen	60-68	catalase	Homo sapiens	175-183
25651845-9	2015	Sequence analysis revealed Thr-315 is a consensus N-linked glycosylation site for Asn-313 and that its elimination significantly (~four- to fivefold) improves the maximum velocity of PC activation by the thrombin-TM complex, explaining the basis for the proband"s negative VTE pedigree.	Nitrogen	50-51	coagulation factor II, thrombin	Homo sapiens	204-212
25713076-4	2015	In vitro, the molybdoenzymes mitochondrial amidoxime reducing component 1 and 2 (mARC1 and mARC2) have shown to be capable of reducing N-hydroxylated base analogs and nucleoside analogs to the corresponding canonical nucleobases and nucleosides upon reconstitution with the electron transport proteins cytochrome b5 and NADH-cytochrome b5 reductase.	Nitrogen	135-136	mitochondrial amidoxime reducing component 1	Homo sapiens	29-79
25713076-4	2015	In vitro, the molybdoenzymes mitochondrial amidoxime reducing component 1 and 2 (mARC1 and mARC2) have shown to be capable of reducing N-hydroxylated base analogs and nucleoside analogs to the corresponding canonical nucleobases and nucleosides upon reconstitution with the electron transport proteins cytochrome b5 and NADH-cytochrome b5 reductase.	Nitrogen	135-136	mitochondrial amidoxime reducing component 2	Mus musculus	81-86
25713076-4	2015	In vitro, the molybdoenzymes mitochondrial amidoxime reducing component 1 and 2 (mARC1 and mARC2) have shown to be capable of reducing N-hydroxylated base analogs and nucleoside analogs to the corresponding canonical nucleobases and nucleosides upon reconstitution with the electron transport proteins cytochrome b5 and NADH-cytochrome b5 reductase.	Nitrogen	135-136	mitochondrial amidoxime reducing component 2	Mus musculus	91-96
25742049-8	2015	Selectivity and reproducibility measurements for the A2-BPMO sample showed quite good performance in flowing N2 gas at 40 mL/min and CO2 gas of 60 mL/min at 25  C.	Nitrogen	109-111	ATPase H+ transporting V0 subunit a2	Homo sapiens	53-60
25682717-6	2015	We find that pH can promote the self-assembly transition of Ace(m)-2-Ace(n) from surfactant monomers to aggregates through protonation between H(+) and the tertiary nitrogen group.	Nitrogen	165-173	angiotensin I converting enzyme	Homo sapiens	60-63
25682717-6	2015	We find that pH can promote the self-assembly transition of Ace(m)-2-Ace(n) from surfactant monomers to aggregates through protonation between H(+) and the tertiary nitrogen group.	Nitrogen	165-173	angiotensin I converting enzyme	Homo sapiens	69-72
25608933-6	2015	In this context, four types of NHC-complexes, i.e., carbon-functionalized NHCs, nitrogen-functionalized NHCs, oxygen-functionalized NHCs and nitrogen/oxygen-functionalized unsymmetric NHCs, are described.	Nitrogen	80-88	high mobility group nucleosomal binding domain 4	Homo sapiens	31-34
25608933-6	2015	In this context, four types of NHC-complexes, i.e., carbon-functionalized NHCs, nitrogen-functionalized NHCs, oxygen-functionalized NHCs and nitrogen/oxygen-functionalized unsymmetric NHCs, are described.	Nitrogen	141-149	high mobility group nucleosomal binding domain 4	Homo sapiens	31-34
25805821-0	2015	N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes.	Nitrogen	0-1	epidermal growth factor receptor	Homo sapiens	34-66
25805821-3	2015	Here we present atomistic MD simulations of the monomeric N-glycosylated human EGFR in biomimetic lipid bilayers that are, in parallel, also used for the reconstitution of full-length receptors.	Nitrogen	58-59	epidermal growth factor receptor	Homo sapiens	79-83
25805821-5	2015	We find that N-glycosylation is a critical determinant of EGFR conformation, and specifically the orientation of the EGFR ectodomain relative to the membrane.	Nitrogen	13-14	epidermal growth factor receptor	Homo sapiens	58-62
25805821-5	2015	We find that N-glycosylation is a critical determinant of EGFR conformation, and specifically the orientation of the EGFR ectodomain relative to the membrane.	Nitrogen	13-14	epidermal growth factor receptor	Homo sapiens	117-121
25439266-4	2015	Compared to baseline concentrations (at 0 min), insulin infusion decreased (P &lt; 0.05) plasma concentrations of glucagon, non-esterified fatty acids (NEFA), lactate, nonessential amino acids (NEAA), branched-chain amino acids (BCAA), total amino acids (TAA) and urea nitrogen (UN).	Nitrogen	269-277	insulin	Homo sapiens	48-55
25622868-4	2015	The milk concentrations of ionic calcium and kappa-casein were reduced as DCAD increased, whereas the milk urea nitrogen and beta-lactoglobulin concentrations were increased.	Nitrogen	112-120	Weaning weight-maternal milk	Bos taurus	102-106
26257575-2	2015	Here we explore approaches to rapid "assembly" of novel photoprecursors with nitrogen/oxygen-rich tethers capable of producing potential pharmacophores and also compatible with subsequent 1,3-dipolar cycloadditions to furnish pentacyclic heterocycles with new structural cores, minimal number of rotatable bonds, and a high content of sp3 hybridized carbons.	Nitrogen	77-85	Sp3 transcription factor	Homo sapiens	335-338
25267364-5	2015	Therefore, UV/PS has the potential to minimize the formation of a range of N-DBPs in organic nitrogen-rich waters where N-DBP precursors are prevalent.	Nitrogen	93-101	D-box binding PAR bZIP transcription factor	Homo sapiens	77-80
25719509-4	2015	On Cu/Pt(100), the selective conversion from NO3(-) to N2 may be achieved.	Nitrogen	55-57	NBL1, DAN family BMP antagonist	Homo sapiens	45-48
25712142-5	2015	HSQC NMR spectroscopy on the (15) N-labeled, monomer Abeta1-40 peptide indicates nonsignificant interaction with monomeric Abeta.	Nitrogen	5-6	amyloid beta precursor protein	Homo sapiens	53-58
25683572-1	2015	When oxygen is limiting in soils and sediments, microorganisms utilize nitrate (NO3-) in respiration--through the process of denitrification--leading to the production of dinitrogen (N2) gas and trace amounts of nitrous (N2O) and nitric (NO) oxides.	Nitrogen	171-181	NBL1, DAN family BMP antagonist	Homo sapiens	80-83
25683572-1	2015	When oxygen is limiting in soils and sediments, microorganisms utilize nitrate (NO3-) in respiration--through the process of denitrification--leading to the production of dinitrogen (N2) gas and trace amounts of nitrous (N2O) and nitric (NO) oxides.	Nitrogen	183-185	NBL1, DAN family BMP antagonist	Homo sapiens	80-83
25826381-0	2015	Correction: the inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.	Nitrogen	30-31	signal transducer and activator of transcription 3	Homo sapiens	85-90
25659754-1	2015	Condensed polycyclic heteroaromatic cations bearing a bridgehead nitrogen with pyridazino[1",6":1,2]pyrido[3,4-b]indolinium and pyridazino[1,6-a]benzimidazolium structures were assayed as inhibitors of LPS-induced TNF-alpha production by THP-1 cells.	Nitrogen	65-73	tumor necrosis factor	Homo sapiens	214-223
25786174-4	2015	Correspondingly, glutamine deprivation or inhibition of N-glycosylation decreased M2 polarization and production of chemokine CCL22.	Nitrogen	56-57	chemokine (C-C motif) ligand 22	Mus musculus	126-131
25719509-5	2015	The Cu sites catalyze the reduction of NO3(-) to NO2(-), and the Pt(100) sites catalyze the reduction of NO2(-) to N2, though in different potential windows.	Nitrogen	115-117	NBL1, DAN family BMP antagonist	Homo sapiens	39-42
25641748-6	2015	We found that addition of a phenyl ring at the 4-nitrogen of MMI yields a compound that is significantly more potent than MMI at inhibiting 24h TNF-alpha-induced VCAM-1 protein expression.	Nitrogen	49-57	tumor necrosis factor	Homo sapiens	144-153
25641748-6	2015	We found that addition of a phenyl ring at the 4-nitrogen of MMI yields a compound that is significantly more potent than MMI at inhibiting 24h TNF-alpha-induced VCAM-1 protein expression.	Nitrogen	49-57	vascular cell adhesion molecule 1	Homo sapiens	162-168
25853013-15	2015	A highly significant correlation was observed between the individual T/N ratio of (11)C-4DST and (18)F-FLT in the tumor (r = 0.79, P = 0.0001).	Nitrogen	71-72	fms related receptor tyrosine kinase 1	Homo sapiens	103-106
25557892-10	2015	Milk urea nitrogen (16.60, 15.58, 15.43, and 14.75 mg/dL) declined with increasing CCDS addition.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
25189707-8	2015	The original chlorine present on the BZF molecule is completely converted to chloride anion and part of the nitrogen is mainly converted to NO3- along with smaller amounts of NO2- and NH4+.	Nitrogen	108-116	NBL1, DAN family BMP antagonist	Homo sapiens	140-143
26117894-7	2015	When NH3 flow rate is 20 mL x min(-1), the spectral line intensity of nitrogen active atom reaches a maximum at the same applied voltage peak-peak value.	Nitrogen	70-78	CD59 molecule (CD59 blood group)	Homo sapiens	30-36
25425164-4	2015	In the presence of NADH, mARC proteins exert N-reductive activity together with the two electron transport proteins cytochrome b5 type B and NADH cytochrome b5 reductase.	Nitrogen	19-20	cytochrome b5 type B	Homo sapiens	116-136
26236871-7	2015	At 1000 m and 2000 m, four-year N and combined N + P additions increased gross mineral N production but decreased NH4+ and NO3- immobilization and DNRA compared to the control.	Nitrogen	32-33	NBL1, DAN family BMP antagonist	Homo sapiens	123-126
26236871-7	2015	At 1000 m and 2000 m, four-year N and combined N + P additions increased gross mineral N production but decreased NH4+ and NO3- immobilization and DNRA compared to the control.	Nitrogen	47-48	NBL1, DAN family BMP antagonist	Homo sapiens	123-126
25576393-11	2015	PPARalpha via HNF4alpha maintains body protein metabolic homeostasis by down-regulating genes involved in amino acid catabolism for preserving body nitrogen.	Nitrogen	148-156	peroxisome proliferator activated receptor alpha	Mus musculus	0-9
25568315-9	2015	Moreover, the formation of this unique structure is critically dependent on the finely tuned interplay between disulfide bonding and N-glycosylation in the membrane processed NBCe1-A dimer.	Nitrogen	133-134	solute carrier family 4 member 4	Homo sapiens	175-182
25659750-4	2015	Here the GL3 and EGL3 proteins were characterized with respect to their affinities for PRODUCTION OF ANTHOCYANIN PIGMENT2 (PAP2), a R2R3-MYB which is induced by nitrogen depletion and is part of MBW complexes promoting anthocyanin synthesis.	Nitrogen	161-169	myb domain protein 90	Arabidopsis thaliana	87-121
25659750-4	2015	Here the GL3 and EGL3 proteins were characterized with respect to their affinities for PRODUCTION OF ANTHOCYANIN PIGMENT2 (PAP2), a R2R3-MYB which is induced by nitrogen depletion and is part of MBW complexes promoting anthocyanin synthesis.	Nitrogen	161-169	myb domain protein 90	Arabidopsis thaliana	123-127
25611163-6	2015	In complex 3, the two terminal octahedral Co(III)N2O4 centers coordinate to the central penta-coordinated Co(II) ion through double phenoxido bridges along with the nitrogen atom of a terminal azido ligand.	Nitrogen	165-173	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	45-48
25548276-10	2015	We conclude that N-glycosylation of Asn-594 of COX-2 occurs in the ER, leading to anterograde movement of COX-2 to the Golgi where the Asn-594-linked glycan is trimmed prior to retrograde COX-2 transport to the ER for ERAD.	Nitrogen	17-18	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	47-52
25548276-10	2015	We conclude that N-glycosylation of Asn-594 of COX-2 occurs in the ER, leading to anterograde movement of COX-2 to the Golgi where the Asn-594-linked glycan is trimmed prior to retrograde COX-2 transport to the ER for ERAD.	Nitrogen	17-18	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	106-111
25548276-10	2015	We conclude that N-glycosylation of Asn-594 of COX-2 occurs in the ER, leading to anterograde movement of COX-2 to the Golgi where the Asn-594-linked glycan is trimmed prior to retrograde COX-2 transport to the ER for ERAD.	Nitrogen	17-18	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	106-111
25469667-2	2015	CoCr surfaces modified by nitrogen plasma immersion ion implantation (PIII) are characterized by improved wear resistance but also showed increased Co(II) ion release under in vitro conditions.	Nitrogen	26-34	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	148-153
24944085-3	2015	Comprehensive mutant analyses of all slac/slah mutants indicated that slah3 plants showed a greater growth defect than wild-type plants when ammonium was supplied as the sole nitrogen source.	Nitrogen	175-183	SLAC1 homologue 3	Arabidopsis thaliana	70-75
25648746-0	2015	Fog-like fluffy structured N-doped carbon with a superior oxygen reduction reaction performance to a commercial Pt/C catalyst.	Nitrogen	27-28	zinc finger protein, FOG family member 1	Homo sapiens	0-3
25648746-1	2015	A high-performance N-doped carbon catalyst with a fog-like, fluffy structure was prepared through pyrolyzing a mixture of polyacrylonitrile, melamine and iron chloride.	Nitrogen	19-20	zinc finger protein, FOG family member 1	Homo sapiens	50-53
25889839-8	2015	Gain- and loss-of-function studies indicated that secretory ITLN1 facilitated the NDRG2 expression, resulting in down-regulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 9 (MMP-9), in NB cell lines SH-SY5Y, SK-N-BE(2), and SK-N-SH.	Nitrogen	63-64	vascular endothelial growth factor A	Homo sapiens	132-166
25218230-1	2015	New Co(II), Ni(II) and Cu(II) complexes derived from tetradentate macrocyclic nitrogen ligand, (1E,4E,8E,12E)-5,8,13,16-tetramethyl-1,4,9,12-tetrazacyclohexadeca-4,8,12,16-tetraene (EDHDH) have been synthesized.	Nitrogen	78-86	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
25706562-1	2015	Arabidopsis ubiquitin ligases ATL31 and homologue ATL6 control the carbon/nitrogen nutrient and pathogen responses.	Nitrogen	74-82	RING/U-box superfamily protein	Arabidopsis thaliana	50-54
25889839-8	2015	Gain- and loss-of-function studies indicated that secretory ITLN1 facilitated the NDRG2 expression, resulting in down-regulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 9 (MMP-9), in NB cell lines SH-SY5Y, SK-N-BE(2), and SK-N-SH.	Nitrogen	63-64	vascular endothelial growth factor A	Homo sapiens	168-172
25639242-4	2015	Nitrogen-stress-induced TORC1 inhibition differs from amino-acid-dependent control of TORC1 and requires the Ssp2 (AMPKalpha) kinase, the Tsc1/2 complex, and Rhb1 GTPase.	Nitrogen	0-8	TSC complex subunit 1	Homo sapiens	138-144
25423599-6	2015	Subsequently, we investigate the effect of N-glycosylation on the function of HCN2 channels.	Nitrogen	43-44	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Homo sapiens	78-82
25537744-6	2015	The AGT ASO resulted in a significant decrease in kidney size, cyst volume density, and blood urea nitrogen.	Nitrogen	99-107	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	4-7
25590985-4	2015	In an effort to understand and improve this behavior, monosubstituted pyridine ligands were used to assess the impact of donor nitrogen basicity on binding strength and stability of fac-[M(I)(CO)3](+) in a 2 + 1 labeling strategy.	Nitrogen	127-135	FA complementation group C	Homo sapiens	182-185
25240298-12	2015	In TNBS-treated mice, supplementation with NS significantly reduced weight loss, and serum proinflammatory cytokine levels (IL-2, IL-6, and IL-12, TNFalpha, IFNgamma) compared with the TNBS group.	Nitrogen	43-45	interleukin 6	Mus musculus	130-134
25658705-2	2015	Nutrient limitation without malnutrition, i.e. dietary restriction, expands CLS through the control of nutrient signaling pathways, of which TOR/Sch9 has proven to be the most relevant, particularly under nitrogen deprivation.	Nitrogen	205-213	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	145-149
25240298-12	2015	In TNBS-treated mice, supplementation with NS significantly reduced weight loss, and serum proinflammatory cytokine levels (IL-2, IL-6, and IL-12, TNFalpha, IFNgamma) compared with the TNBS group.	Nitrogen	43-45	tumor necrosis factor	Mus musculus	147-155
25240298-12	2015	In TNBS-treated mice, supplementation with NS significantly reduced weight loss, and serum proinflammatory cytokine levels (IL-2, IL-6, and IL-12, TNFalpha, IFNgamma) compared with the TNBS group.	Nitrogen	43-45	interferon gamma	Mus musculus	157-165
25523083-2	2015	The LexA protein of the nitrogen-fixing cyanobacterium, Anabaena sp.	Nitrogen	24-32	DNA repair system	Escherichia coli	4-8
25196629-7	2015	After controlling for several covariates and especially urinary nitrogen (the biomarker of protein intake) cortisol secretion  C21 was inversely associated with all analyzed pQCT measures of bone quality.	Nitrogen	64-72	TBL1X/Y related 1	Homo sapiens	127-130
25146936-0	2015	The QQS orphan gene of Arabidopsis modulates carbon and nitrogen allocation in soybean.	Nitrogen	56-64	qua-quine starch	Arabidopsis thaliana	4-7
25399019-4	2015	Tef has a tall and weak stem, liable to lodge (or fall over), which is aggravated by wind, rain, or application of nitrogen fertilizer.	Nitrogen	115-123	TEF transcription factor, PAR bZIP family member	Homo sapiens	0-3
25505062-6	2015	More specifically, we find that the number of N-glycosylated residues in gPr80 inversely correlates with the sensitivity of a gammaretrovirus to deamination by mouse A3 and also, surprisingly, by human A3G.	Nitrogen	46-47	cholinergic receptor, nicotinic, alpha polypeptide 3	Mus musculus	166-168
25505062-6	2015	More specifically, we find that the number of N-glycosylated residues in gPr80 inversely correlates with the sensitivity of a gammaretrovirus to deamination by mouse A3 and also, surprisingly, by human A3G.	Nitrogen	46-47	apolipoprotein B mRNA editing enzyme catalytic subunit 3G	Homo sapiens	202-205
25237846-4	2015	The genes upregulated through IFN-gamma were involved in cell cycle; regulation of cell proliferation; programmed cell death; chemotaxis; and cytokine, growth factor, and peptidase activity, whereas the genes downregulated through IFN-gamma primarily contributed to the regulation of transcription, cell-cell signaling, nitrogen compound biosynthesis, ser/thr protein kinase signaling, and regulation of the Wnt pathway.	Nitrogen	320-328	interferon gamma	Mus musculus	30-39
25237846-4	2015	The genes upregulated through IFN-gamma were involved in cell cycle; regulation of cell proliferation; programmed cell death; chemotaxis; and cytokine, growth factor, and peptidase activity, whereas the genes downregulated through IFN-gamma primarily contributed to the regulation of transcription, cell-cell signaling, nitrogen compound biosynthesis, ser/thr protein kinase signaling, and regulation of the Wnt pathway.	Nitrogen	320-328	interferon gamma	Mus musculus	231-240
25146936-8	2015	These data broaden the concept of QQS as a modulator of carbon and nitrogen allocation, and demonstrate that this species-specific gene can affect the seed composition of an agronomic species thought to have diverged from Arabidopsis 100 million years ago.	Nitrogen	67-75	qua-quine starch	Arabidopsis thaliana	34-37
25494936-6	2015	First, we found that THB1 and THB2 expression is modulated by the nitrogen source and depends on NIT2, a transcription factor required for nitrate assimilation genes expression.	Nitrogen	66-74	uncharacterized protein	Chlamydomonas reinhardtii	21-25
25262938-0	2015	N-Glycosylation of apolipoprotein A1 in cardiovascular diseases.	Nitrogen	0-1	apolipoprotein A1	Homo sapiens	19-36
25513968-6	2015	Compared to JDTic, the N-fluoropropyl derivative 2 bound to KOR with an only 4-fold lower affinity and a higher selectivity relative to MOR and DOR [Ki(kappa) = 1.6 nM; Ki(mu)/Ki(kappa) = 12; Ki(delta)/Ki(kappa) = 159 for 2versus Ki(kappa) = 0.42 nM; Ki(mu)/Ki(kappa) = 9; Ki(delta)/Ki(kappa) = 85 for JDTic].	Nitrogen	23-24	tumor protein p53 inducible nuclear protein 2	Homo sapiens	144-147
25495542-10	2015	In addition, chemical compounds containing more halogen atoms, unsaturated alkanes chains relevant to pi-pi stacking, and fewer nitrogen atoms tend to be PXR activators.	Nitrogen	128-136	nuclear receptor subfamily 1 group I member 2	Homo sapiens	154-157
25105264-3	2015	The infrared spectra of Co(II), Ni(II) and Cu(II) complexes indicate a bidentate type of bonding for APC through the exocyclic amino and adjacent pyrimidine nitrogen as donors whereas APC coordinated to Pd(II) ion as a monodentated ligand via a pyrimidine nitrogen donor.	Nitrogen	157-165	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	24-30
25105264-3	2015	The infrared spectra of Co(II), Ni(II) and Cu(II) complexes indicate a bidentate type of bonding for APC through the exocyclic amino and adjacent pyrimidine nitrogen as donors whereas APC coordinated to Pd(II) ion as a monodentated ligand via a pyrimidine nitrogen donor.	Nitrogen	256-264	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	24-30
25205244-8	2015	We show that FAAH uses an exquisite catalytic strategy to induce amide bond distortion, reactive nitrogen inversion, and amide bond hydrolysis, promoting catalysis to completion.	Nitrogen	97-105	fatty acid amide hydrolase	Homo sapiens	13-17
25407563-5	2015	It was observed that in each case, a magnesium-carbon bond was inserted into the carbon-nitrogen double bond of either carbodiimides or Dipp2DAD resulting in a monoanionic amido-imino ligand.	Nitrogen	88-96	nudix hydrolase 4	Homo sapiens	136-141
25205244-0	2015	Anandamide hydrolysis in FAAH reveals a dual strategy for efficient enzyme-assisted amide bond cleavage via nitrogen inversion.	Nitrogen	108-116	fatty acid amide hydrolase	Homo sapiens	25-29
25451932-0	2015	Distinct roles of N-glycosylation at different sites of corin in cell membrane targeting and ectodomain shedding.	Nitrogen	18-19	corin, serine peptidase	Homo sapiens	56-61
25451932-2	2015	Human corin has 19 predicted N-glycosylation sites in its extracellular domains.	Nitrogen	29-30	corin, serine peptidase	Homo sapiens	6-11
25451932-5	2015	In this study, we examined corin mutants, in which each of the 19 predicted N-glycosylation sites was mutated individually.	Nitrogen	76-77	corin, serine peptidase	Homo sapiens	27-32
25451932-6	2015	By Western analysis of corin proteins in cell lysate and conditioned medium from transfected HEK293 cells and HL-1 cardiomyocytes, we found that N-glycosylation at Asn-80 inhibited corin shedding in the juxtamembrane domain.	Nitrogen	145-146	corin, serine peptidase	Homo sapiens	23-28
25451932-6	2015	By Western analysis of corin proteins in cell lysate and conditioned medium from transfected HEK293 cells and HL-1 cardiomyocytes, we found that N-glycosylation at Asn-80 inhibited corin shedding in the juxtamembrane domain.	Nitrogen	145-146	corin, serine peptidase	Homo sapiens	181-186
25451932-7	2015	Similarly, N-glycosylation at Asn-231 protected corin from autocleavage in the frizzled-1 domain.	Nitrogen	11-12	corin, serine peptidase	Homo sapiens	48-53
25451932-8	2015	Moreover, N-glycosylation at Asn-697 in the scavenger receptor domain and at Asn-1022 in the protease domain is important for corin cell surface targeting and zymogen activation.	Nitrogen	10-11	corin, serine peptidase	Homo sapiens	126-131
25451932-10	2015	N-Glycosylation at Asn-1022 may be switched to different sites to promote corin zymogen activation.	Nitrogen	0-1	corin, serine peptidase	Homo sapiens	74-79
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	Nitrogen	81-82	carboxypeptidase A4	Homo sapiens	39-43
25877036-7	2015	And the damage of neuron increased versus I/R+NS group, brain infarction volume [(76 +- 6) vs (140 +- 10) mm(3)] and the expressions of astrocytic CX43 and GFAP were lower in I/R+Gap26 group [CX43: (0.43 +- 0.16) vs (2.15 +- 0.73); GFAP: (57 +- 6) vs (140 +- 9), P &lt; 0.05] and neuronal damage lessened.	Nitrogen	46-48	gap junction protein, alpha 1	Rattus norvegicus	192-196
25475885-4	2015	In vitro analyses using liver microsomes from individual humans in correlation assays and recombinantly expressed P450 enzymes revealed that CYP2D6 was the major contributor to mirtazapine 8-hydroxylation with high affinity, and that CYP3A5 catalyzed N-demethylation in a similar high-capacity manner to that of CYP3A4.	Nitrogen	251-252	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	141-147
25475885-4	2015	In vitro analyses using liver microsomes from individual humans in correlation assays and recombinantly expressed P450 enzymes revealed that CYP2D6 was the major contributor to mirtazapine 8-hydroxylation with high affinity, and that CYP3A5 catalyzed N-demethylation in a similar high-capacity manner to that of CYP3A4.	Nitrogen	251-252	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	234-240
25462269-4	2015	Therefore, we reduced the basic character of the N-atom present in these ligands, and we obtained potent P-gp modulators with poor or null sigma2 receptor affinity.	Nitrogen	49-50	ATP binding cassette subfamily B member 1	Homo sapiens	105-109
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	Nitrogen	81-82	serpin family A member 1	Homo sapiens	45-48
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	Nitrogen	81-82	haptoglobin	Homo sapiens	50-52
26077503-8	2015	The average runoff volume was 289 mm (varied from 221 to 357 mm), which contained 15.7 (varied from 3.3 to 39.2 mg L-1) mg L-1 total N.	Nitrogen	133-134	immunoglobulin kappa variable 1-16	Homo sapiens	123-126
25305627-1	2015	OBJECTIVES: Transferrin variants can hinder the diagnostic process in cases of suspected Congenital disorders of glycosylation which affect N-Glycosylation.	Nitrogen	140-141	transferrin	Homo sapiens	12-23
26106251-7	2015	Serum PGRN concentrations in all individuals positively and markedly correlated with systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass index (BMI), triglyceride (TG), urinary albumin excretion rate (UAER), blood urea nitrogen (BUN), creatinine (CRE), white blood cell (WBC), disease duration, IL-6, and TNF-alpha, while correlating negatively and significantly with eGFR.	Nitrogen	240-248	granulin precursor	Homo sapiens	6-10
25327846-0	2015	Introduction of a nitrogen-containing side chain appended on C-10 of cethromycin leads to reduced CYP3A4 inhibition (WO2014049356A1).	Nitrogen	18-26	homeobox C10	Homo sapiens	61-65
25327846-0	2015	Introduction of a nitrogen-containing side chain appended on C-10 of cethromycin leads to reduced CYP3A4 inhibition (WO2014049356A1).	Nitrogen	18-26	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	98-104
25053090-6	2015	The IC50 values (muM) of nitrogen radical scavenging activity were 24.48, 17.51 and 6.81 for betanin, phyllocactin and betanidin.	Nitrogen	25-33	latexin	Homo sapiens	17-20
25449705-4	2015	The putative StmGILT protein possesses all the main characteristics of known GILT proteins, including a signature sequence, a reductase active site CXXC, twelve conserved cysteines, and two potential N-linked glycosylation sites.	Nitrogen	200-201	gamma-interferon-responsive lysosomal thiol protein	Cucumis sativus	16-20
25282184-0	2015	Prothrombin complex concentrate (Beriplex P/N)-related renal and cerebral infarctions in a patient with warfarin-associated intracerebral hemorrhage.	Nitrogen	44-45	coagulation factor II, thrombin	Homo sapiens	0-11
25898651-2	2015	The results showed that: (1) the contents of the total nitrogen (TN) were between 389 and 3865 mg x kg(-1), and the spatial distribution showed an overall downward trend in the "Five River", the "Hu Xin" and the northern regions; the contents of the transferable total nitrogen (TTN) were between 319.36 and 904.56 mg x kg(-1) and contributed 52% to the TN, and its spatial distribution trend was the same as that of TN.	Nitrogen	55-63	xin actin binding repeat containing 1	Homo sapiens	199-202
24738549-2	2015	Urease is present to a greater abundance in plants and plays significant role related to nitrogen recycling from urea.	Nitrogen	89-97	urease	Arabidopsis thaliana	0-6
25778329-6	2015	Positive correlation was observed between sApo-2L and aspartate aminotransferase (AST) in benign peritoneal fluid and sCD200, and creatinine and sCD200 and platelets in OC patients; also, sCD200 and CEA in EC patients and sCD200 and blood urea nitrogen (BUN) in healthy subjects.	Nitrogen	244-252	solute carrier family 17 member 5	Homo sapiens	82-85
24910250-8	2015	The GB5 strains varied from other genotypes in the central conserved region and N-glycosylation sites.	Nitrogen	80-81	G protein subunit beta 5	Homo sapiens	4-7
26261057-8	2015	The mass spectra of the N-glycosylated peptide revealed that the observed biological properties were attributable to the characteristic N-glycan structures of the anti-CD20 mAbs produced in the transgenic silkworms, i.e., the lack of the core-fucose and galactose at the non-reducing terminal.	Nitrogen	24-25	keratin 20	Homo sapiens	168-172
25349282-9	2015	We further traced QTLs down to single-nucleotide resolution and uncovered loss-of-function mutations in RIM15, PUT4, DAL1, and DAL4 as the genetic basis for nitrogen source use variations.	Nitrogen	157-165	protein kinase RIM15	Saccharomyces cerevisiae S288C	104-109
25697523-3	2015	We first outline the methods for large-scale production of stable, functional rhodopsin containing (13)C- and (15)N-labeled amino acids.	Nitrogen	114-115	rhodopsin	Homo sapiens	78-87
25702115-5	2015	CFTR is a glycoprotein that undergoes complex N-glycosylation as it passes through Golgi-mediated conventional exocytosis.	Nitrogen	46-47	CF transmembrane conductance regulator	Homo sapiens	0-4
25349282-9	2015	We further traced QTLs down to single-nucleotide resolution and uncovered loss-of-function mutations in RIM15, PUT4, DAL1, and DAL4 as the genetic basis for nitrogen source use variations.	Nitrogen	157-165	allantoinase	Saccharomyces cerevisiae S288C	117-121
25807209-0	2015	Rice ubiquitin ligase EL5 prevents root meristematic cell death under high nitrogen conditions and interacts with a cytosolic GAPDH.	Nitrogen	75-83	epilepsy 5	Mus musculus	22-25
25407617-6	2015	On average, 52-59% of N deposition was intercepted by the canopy, the retention being higher for NH4(+) (60-67%) than for NO3(-) (45-54%).	Nitrogen	22-23	NBL1, DAN family BMP antagonist	Homo sapiens	122-128
25407620-8	2015	NO3 (-) concentrations in streams were low and had natural abundance (18)O values consistent with microbial production, demonstrating that atmospheric N is being biologically transformed while moving through these watersheds and that these forested watersheds are unlikely to be N saturated.	Nitrogen	151-152	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
26368055-3	2015	On carbon or nitrogen starvation medium, atg5 colonies turned yellow earlier than the wild-type (WT) colonies, showing that Physcomitrella atg5 mutants, like yeast and Arabidopsis, are sensitive to nutrient starvation.	Nitrogen	13-21	Atg5p	Saccharomyces cerevisiae S288C	41-45
26368055-3	2015	On carbon or nitrogen starvation medium, atg5 colonies turned yellow earlier than the wild-type (WT) colonies, showing that Physcomitrella atg5 mutants, like yeast and Arabidopsis, are sensitive to nutrient starvation.	Nitrogen	13-21	Atg5p	Saccharomyces cerevisiae S288C	139-143
26252500-5	2015	THB1 and THB2 are regulated by the nitrogen source and respond differentially to NO and the nitrate/ammonium balance.	Nitrogen	35-43	uncharacterized protein	Chlamydomonas reinhardtii	0-4
25807209-5	2015	These results indicate that impairment of EL5 function activates nitrogen signaling despite the absence of a nitrogen source.	Nitrogen	65-73	epilepsy 5	Mus musculus	42-45
25281312-9	2014	CD4 (+)CD25 (+)Treg cells were negatively correlated with blood urea nitrogen, supernatant IL-4 and proteinuria in IgAN patients, and positively with estimated glomerular filtration rate.	Nitrogen	69-77	CD4 molecule	Homo sapiens	0-3
25670875-4	2014	GABA-transaminase (gamma-aminobutyric acid) is found to play very important role in nitrogen recycling process through GABA-shunt.	Nitrogen	84-92	4-aminobutyrate aminotransferase	Homo sapiens	0-17
25354954-0	2014	Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 (SPPL3) regulates cellular N-glycosylation.	Nitrogen	99-100	signal peptide peptidase like 3	Homo sapiens	40-71
25354954-0	2014	Shedding of glycan-modifying enzymes by signal peptide peptidase-like 3 (SPPL3) regulates cellular N-glycosylation.	Nitrogen	99-100	signal peptide peptidase like 3	Homo sapiens	73-78
25354954-4	2014	We demonstrate that SPPL3 alters the pattern of cellular N-glycosylation by triggering the proteolytic release of active site-containing ectodomains of glycosidases and glycosyltransferases such as N-acetylglucosaminyltransferase V, beta-1,3 N-acetylglucosaminyltransferase 1 and beta-1,4 galactosyltransferase 1.	Nitrogen	57-58	signal peptide peptidase like 3	Homo sapiens	20-25
25266909-1	2014	Nitrogen-doped TiO2 nanoparticles have been synthesized using sol-gel methods and subsequently fluorinated at room temperature by aging in acidic solutions of NaF.	Nitrogen	0-8	C-X-C motif chemokine ligand 8	Homo sapiens	159-162
25351391-0	2014	Isotopic analysis of N and O in NO3- by selective bacterial reduction to N2O for groundwater pollution.	Nitrogen	21-22	NBL1, DAN family BMP antagonist	Homo sapiens	32-35
25793220-2	2015	Clinoptilolite zeolite and compost could be used to control N loss from urea by controlling NH4 (+) and NO3 (-) release from urea.	Nitrogen	60-61	NBL1, DAN family BMP antagonist	Homo sapiens	104-107
25633946-8	2015	Nitrogen and phosphorus emissions increase by about 70% under both SSP scenarios, with the largest increase in SSP1.	Nitrogen	0-8	SUMO specific peptidase 6	Homo sapiens	111-115
25474158-12	2014	The interaction between rPCN and TLR2 depended on carbohydrate recognition because it was affected by mutation of the receptor"s N-glycosylation sites.	Nitrogen	27-28	toll like receptor 2	Homo sapiens	33-37
24093431-2	2014	METHODS: Insulin nanoparticles were prepared from methylated N-(4-N,N-dimethylaminobenzyl), methylated N-(4 pyridinyl) and methylated N-(benzyl).	Nitrogen	61-62	insulin	Homo sapiens	9-16
24093431-2	2014	METHODS: Insulin nanoparticles were prepared from methylated N-(4-N,N-dimethylaminobenzyl), methylated N-(4 pyridinyl) and methylated N-(benzyl).	Nitrogen	66-67	insulin	Homo sapiens	9-16
25812217-8	2014	A NetNGlyc server analysis at the Technical University of Denmark (www.cbs.dtu.dk/services/NetNGlyc/) was used to predict N-glycosylation in GP5 sequences.	Nitrogen	2-3	glycoprotein V platelet	Homo sapiens	141-144
25089794-4	2014	Data showed positive effects of n-3 PUFA on muscle fatty acid composition: ALA+137%, EPA+188%, DPA+51% and DHA+12%.	Nitrogen	32-33	Polyunsaturated fatty acid percentage	Sus scrofa	36-40
25876414-0	2014	[Effects of irrigation of untreated livestock farm wastewater on accumulation and vertical mig- ration of nitrogen and phosphorus in paddy soil].	Nitrogen	106-114	C-X-C motif chemokine ligand 9	Homo sapiens	91-94
25329966-4	2014	With nitrogen nucleophiles, the SN2 at bromine channel is suppressed.	Nitrogen	5-13	solute carrier family 38 member 5	Homo sapiens	32-35
25336660-4	2014	Here, we report that in estrogen receptor (ER)alpha-negative, but not -positive, breast cancer cells ADAM8 contains N-glycosylation, which is required for its correct processing and activation.	Nitrogen	116-117	estrogen receptor 1	Homo sapiens	24-41
25329565-4	2014	Adsorption isotherms suggest that sorption of Pb(II) on GO-NH2 nanosheets is monolayer coverage, and adsorption is controlled by a chemical process involving the surface complexation of Pb(II) ions with the nitrogen-containing groups on the surface of GO-NH2.	Nitrogen	207-215	submaxillary gland androgen regulated protein 3B	Homo sapiens	46-52
25329565-4	2014	Adsorption isotherms suggest that sorption of Pb(II) on GO-NH2 nanosheets is monolayer coverage, and adsorption is controlled by a chemical process involving the surface complexation of Pb(II) ions with the nitrogen-containing groups on the surface of GO-NH2.	Nitrogen	207-215	submaxillary gland androgen regulated protein 3B	Homo sapiens	186-192
25484625-4	2014	RESULT: Notably, comparative analyses also revealed that MCF-7 cells produced differentially N-glycosylated forms of haptoglobin.	Nitrogen	8-9	haptoglobin	Homo sapiens	117-128
25242514-4	2014	MAIN METHODS: We generated rat SP-A constructs with two types of mutations that impair its glycosylation: N-glycosylation site mutations (N21T, N207S and N21T/N207S) and disease-associated CRD mutations (G231V, F198S).	Nitrogen	3-4	surfactant protein A1	Rattus norvegicus	31-35
25274042-6	2014	The increased anion loading in the channels of Co(III)-based MOF 1 relative to Ni(II)-based MOF 2 results in increased selectivity for CO2 over N2 but a decrease in the sorption kinetics and storage capacity of the framework.	Nitrogen	144-146	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	47-53
25238963-3	2014	To study how changes in fucosylation impact embryonic development, we up-regulated N-linked fucosylation via over-expression of a key GDP-Fucose transporter, Slc35c1, in zebrafish.	Nitrogen	83-84	solute carrier family 35 member C1	Danio rerio	158-165
25238963-7	2014	Moreover, we provide biochemical evidence that this decrease is associated with reduced Wnt8 ligand and elevated Lrp6 coreceptor, which we show are both substrates for N-linked fucosylation in zebrafish embryos.	Nitrogen	168-169	low density lipoprotein receptor-related protein 6	Danio rerio	113-117
25243720-2	2014	As the influence of N-glycosylation on the in vivo activities of IL-6 could not be elucidated so far, a semisynthesis of homogeneous glycoforms of IL-6 was established by sequential native chemical ligation.	Nitrogen	20-21	interleukin 6	Homo sapiens	147-151
25324306-8	2014	In short, phosphorylation on novel N-term sites of hnRNPA1 promotes translation of anti-apoptotic proteins and is indispensable for the pro-survival effects of FGF-2.	Nitrogen	35-36	fibroblast growth factor 2	Homo sapiens	160-165
25369456-2	2014	In this study, 380 nitrogen compounds were administered to three S. cerevisiae flor strains handling Flo11p alleles with different expression levels.	Nitrogen	19-27	Flo11p	Saccharomyces cerevisiae S288C	101-107
25280017-3	2014	Because the N2 selectivity is determined at the nitrite (NO2-) reduction step on the Pd surface, which occurs after NO3- is decomposed into NO2- on the secondary metallic catalyst, we here performed density functional theory (DFT) calculations and experiments to investigate the NO2- reduction pathway on the Pd surface activated by hydrogen.	Nitrogen	12-14	NBL1, DAN family BMP antagonist	Homo sapiens	116-119
25281559-0	2014	Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of alpha-mannosidase under nitrogen starvation conditions.	Nitrogen	108-116	alpha-mannosidase	Saccharomyces cerevisiae S288C	84-101
25281559-1	2014	In Saccharomyces cerevisiae, under nitrogen-starvation conditions, the alpha-mannosidase Ams1 is recognized by the autophagic receptor Atg34 and transported into the vacuole, where it functions as an active enzyme.	Nitrogen	35-43	alpha-mannosidase	Saccharomyces cerevisiae S288C	71-88
25281559-1	2014	In Saccharomyces cerevisiae, under nitrogen-starvation conditions, the alpha-mannosidase Ams1 is recognized by the autophagic receptor Atg34 and transported into the vacuole, where it functions as an active enzyme.	Nitrogen	35-43	alpha-mannosidase	Saccharomyces cerevisiae S288C	89-93
24595981-9	2014	EPO activates signaling cascades that increase the brain"s resistance to ischemia-reperfusion stress by stabilizing mitochondrial membranes, limiting formation of reactive oxygen and nitrogen intermediates, and suppressing pro-inflammatory cytokine production and neutrophil infiltration.	Nitrogen	183-191	erythropoietin	Homo sapiens	0-3
25036722-6	2014	BCRP substrate specificity is quite low as it interacts with a spectrum of substances with only a few common features: hydrophobic and aromatic regions, possibly a flat conformation and the metal ion-, oxygen- and nitrogen-containing functionalities, most of which may be the donors/acceptors of H-bonds.	Nitrogen	214-222	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	0-4
25283837-4	2014	Compositions of isotopes and chemistry indicated that NO3(-) originated mainly from soil N, sewage and livestock wastes and atmospheric nitrogen.	Nitrogen	136-144	NBL1, DAN family BMP antagonist	Homo sapiens	54-57
25379385-8	2014	These results indicate that the defect of N-glycosylation in ECM1 is not involved in the aberration of secretion of LP-derived mutated ECM1.	Nitrogen	42-43	extracellular matrix protein 1	Homo sapiens	61-65
25264579-10	2014	The presence of nitrogen atoms at the surface of these copolymer latex particles was confirmed via X-ray photoelectron spectroscopy studies; these secondary amine groups allow covalent cross-linking via PPG-TDI when adsorbed at the surface of n-dodecane droplets at TBAEMA comonomer contents as low as 40 mol %.	Nitrogen	16-24	serglycin	Homo sapiens	203-206
25340554-0	2014	The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.	Nitrogen	18-19	signal transducer and activator of transcription 3	Homo sapiens	73-78
25340554-0	2014	The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.	Nitrogen	18-19	interleukin 6	Homo sapiens	93-97
25255466-0	2014	Initial excited-state dynamics of an N-alkylated indanylidene-pyrroline (NAIP) rhodopsin analog.	Nitrogen	37-38	rhodopsin	Homo sapiens	79-88
25379385-0	2014	N-Glycosylation of extracellular matrix protein 1 (ECM1) regulates its secretion, which is unrelated to lipoid proteinosis.	Nitrogen	0-1	extracellular matrix protein 1	Homo sapiens	19-49
25207853-5	2014	This method was first applied to determine the N-sialoglycan occupancy rates of two glycosites on human transferrin.	Nitrogen	47-48	transferrin	Homo sapiens	104-115
25379385-0	2014	N-Glycosylation of extracellular matrix protein 1 (ECM1) regulates its secretion, which is unrelated to lipoid proteinosis.	Nitrogen	0-1	extracellular matrix protein 1	Homo sapiens	51-55
25379385-5	2014	As ECM1 has three putative N-glycosylation sites and most of mutated ECM1 observed in LP patients are defective in these N-glycosylation sites, we investigated the correlation between LP and N-glycosylation of ECM1.	Nitrogen	27-28	extracellular matrix protein 1	Homo sapiens	3-7
25379385-6	2014	We identified that the Asn(354) and Asn(444) residues in ECM1 were N-glycosylated by mass spectrometry analysis.	Nitrogen	67-68	extracellular matrix protein 1	Homo sapiens	57-61
25019684-4	2014	Results show that in the presence of calcium, N-myristoylation significantly increases the kinetic rate of VILIP adsorption to the membrane.	Nitrogen	46-47	visinin like 1	Homo sapiens	107-112
25208126-4	2014	Microcosm studies indicated that NO3(-) removal was mainly attributable to denitrification within the diffuse biomat (i.e., 80 +- 20%), with accretion of assimilated nitrogen accounting for less than 3% of the NO3(-) removed.	Nitrogen	166-174	NBL1, DAN family BMP antagonist	Homo sapiens	33-36
25208126-7	2014	The annual temperature-corrected areal first-order NO3(-) removal rate (k20 = 59.4 +- 6.2 m yr(-1)) was higher than values reported for more than 75% of vegetated wetlands that treated water in which NO3(-) was the primary nitrogen species (e.g., nitrified secondary wastewater effluent and agricultural runoff).	Nitrogen	223-231	NBL1, DAN family BMP antagonist	Homo sapiens	51-54
23894062-8	2014	We showed a SOST peptide (SOST-S146, with homology to a bacterial glycotransferase peptide) binds to a NOG peptide (NOG-N54), which contains a N-glycosylation site.	Nitrogen	103-104	sclerostin	Homo sapiens	12-16
23894062-8	2014	We showed a SOST peptide (SOST-S146, with homology to a bacterial glycotransferase peptide) binds to a NOG peptide (NOG-N54), which contains a N-glycosylation site.	Nitrogen	103-104	sclerostin	Homo sapiens	26-30
25019684-8	2014	Taken together, these results show the major kinetic role of N-myristoylation for membrane binding, and highlight the critical role of specific phosphoinositide interactions for membrane association of members of the VILIP family.	Nitrogen	61-62	visinin like 1	Homo sapiens	217-222
25005136-4	2014	To determine if LHT6 plays a role in nitrogen acquisition at soil amino acid concentrations, growth and uptake studies were performed with low levels of toxic amino acid analogues and radiolabelled amino acids, respectively.	Nitrogen	37-45	Transmembrane amino acid transporter family protein	Arabidopsis thaliana	16-20
25108857-13	2014	Milk concentration of solids-not-fat was lesser, whereas milk urea nitrogen was greater for cows fed RM than for those fed CS.	Nitrogen	67-75	Weaning weight-maternal milk	Bos taurus	57-61
25085507-2	2014	Previous studies in yeast have shown that three GTPases-Gtr1, Gtr2, and Rho1-bind to TORC1 in nitrogen and amino acid starvation conditions to block phosphorylation of the S6 kinase Sch9 and activate protein phosphatase 2A (PP2A).	Nitrogen	94-102	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	182-186
25085507-7	2014	Second, in osmotic stress, the MAPK Hog1/p38 drives the TORC1 pathway into a different state, in which Sch9 signaling and PP2A-branch signaling are inhibited, but PP2A-branch signaling can still be activated by nitrogen starvation.	Nitrogen	211-219	mitogen-activated protein kinase HOG1	Saccharomyces cerevisiae S288C	36-40
25238198-1	2014	Reaction of a tris(beta-diketimine) cyclophane, H3L, with benzyl potassium followed by [Cu(OTf)]2(C6H6) affords a tricopper(I) complex containing a bridging dinitrogen ligand.	Nitrogen	157-167	H3 clustered histone 2	Homo sapiens	48-51
25065551-0	2014	The Arabidopsis nitrate transporter NRT2.5 plays a role in nitrate acquisition and remobilization in nitrogen-starved plants.	Nitrogen	101-109	nitrate transporter 2:1	Arabidopsis thaliana	36-40
25942901-2	2014	The amino group consisting of DIPAS was chosen in order to obtain a high adsorption energy because its lone-pair electrons in the N atom would help in the adsorption of DIPAS.	Nitrogen	130-131	PAPPA antisense RNA 1	Homo sapiens	30-35
25942901-2	2014	The amino group consisting of DIPAS was chosen in order to obtain a high adsorption energy because its lone-pair electrons in the N atom would help in the adsorption of DIPAS.	Nitrogen	130-131	PAPPA antisense RNA 1	Homo sapiens	169-174
25274813-2	2014	Mutations that abolish N-terminal glycosylation of rhodopsin (T4K and T17M) cause sector RP in which the inferior retina preferentially degenerates, possibly due to greater light exposure of this region.	Nitrogen	23-24	rhodopsin, gene2 L homeolog	Xenopus laevis	51-60
25065551-3	2014	In this study, we show that Arabidopsis NITRATE TRANSPORTER 2.5 (NRT2.5) is a plasma membrane-localized high-affinity nitrate transporter playing an essential role in adult plants under severe nitrogen starvation.	Nitrogen	193-201	nitrate transporter 2:1	Arabidopsis thaliana	65-69
25065551-4	2014	NRT2.5 expression is induced under nitrogen starvation and NRT2.5 becomes the most abundant transcript amongst the seven NRT2 family members in shoots and roots of adult plants after long-term starvation.	Nitrogen	35-43	nitrate transporter 2:1	Arabidopsis thaliana	0-4
25065551-4	2014	NRT2.5 expression is induced under nitrogen starvation and NRT2.5 becomes the most abundant transcript amongst the seven NRT2 family members in shoots and roots of adult plants after long-term starvation.	Nitrogen	35-43	nitrate transporter 2:1	Arabidopsis thaliana	59-63
25065551-4	2014	NRT2.5 expression is induced under nitrogen starvation and NRT2.5 becomes the most abundant transcript amongst the seven NRT2 family members in shoots and roots of adult plants after long-term starvation.	Nitrogen	35-43	nitrate transporter 2:1	Arabidopsis thaliana	59-63
25065551-8	2014	Growth analyses of multiple mutants between NRT2.1, NRT2.2, NRT2.4, and NRT2.5 revealed that NRT2.5 is required to support growth of nitrogen-starved adult plants by ensuring the efficient uptake of nitrate collectively with NRT2.1, NRT2.2 and NRT2.4 and by taking part in nitrate loading into the phloem during nitrate remobilization.	Nitrogen	133-141	nitrate transporter 2:1	Arabidopsis thaliana	225-231
24821012-1	2014	BACKGROUND: Investigate the impact of natural N- or C-terminal post-translational truncations of lens mature fiber cell Aquaporin 0 (AQP0) on water permeability (Pw) and cell-to-cell adhesion (CTCA) functions.	Nitrogen	8-9	major intrinsic protein of lens fiber	Mus musculus	133-137
24805886-0	2014	Interactions of cytochrome C with N-acylated phosphatidylethanolamine lipids.	Nitrogen	34-35	cytochrome c, somatic	Homo sapiens	16-28
25162139-4	2014	It was observed that when the pull-off velocity varies from 0.02 to 1500 mum/s, there is 100-200% increase in adhesion force in water while it has a 100% increase in nitrogen and hexane.	Nitrogen	166-174	latexin	Homo sapiens	73-76
25995969-10	2014	RESULTS: Compared with control mice, hOXR1-MSCs administration showed significantly decreased blood urea nitrogen (BUN), proteinuria and ameliorated renal pathological damage.	Nitrogen	105-113	oxidation resistance 1	Homo sapiens	37-42
25063813-5	2014	The quality of the nitrogen source, as defined by its ability to promote growth and glutamine accumulation, directly correlates with its ability to activate TORC1 as measured by Sch9 phosphorylation.	Nitrogen	19-27	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	178-182
25063813-6	2014	Preferred nitrogen sources stimulate rapid, sustained Sch9 phosphorylation and glutamine accumulation.	Nitrogen	10-18	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	54-58
25063813-8	2014	Poor nitrogen sources stimulate rapid but transient Sch9 phosphorylation.	Nitrogen	5-13	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	52-56
25255762-1	2014	The reactions of the benzimidazole nitrogen atoms and the exocyclic amino group of 2-aminobenzimidazole with CS2 in NaOH basic medium followed by methylation with methyl iodide was explored.	Nitrogen	35-43	chorionic somatomammotropin hormone 2	Homo sapiens	109-112
24786828-2	2014	In yeast, the Nitrogen permease regulators 2 and 3 (Npr2 and Npr3) mediate an essential response to amino-acid limitation upstream of TORC1.	Nitrogen	14-22	Npr3p	Saccharomyces cerevisiae S288C	61-65
24860154-2	2014	It is metabolized primarily by the cytochrome P450 isoenzyme 3A4 (CYP3A4) to a less-active N-monodesmethyl metabolite.	Nitrogen	91-92	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	35-64
25001409-1	2014	In Saccharomyces cerevisiae, when a rich nitrogen source such as ammonium is added to the culture medium, the general amino acid permease Gap1p is ubiquitinated by the yeast Nedd4-like ubiquitin ligase Rsp5p, followed by its endocytosis to the vacuole.	Nitrogen	41-49	amino acid permease GAP1	Saccharomyces cerevisiae S288C	138-143
24860154-2	2014	It is metabolized primarily by the cytochrome P450 isoenzyme 3A4 (CYP3A4) to a less-active N-monodesmethyl metabolite.	Nitrogen	91-92	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	66-72
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	154-157
25193828-6	2014	The areas showing predicted nitrate concentrations in the leachate above the EU groundwater quality standard of 50mg NO3(-)/L have been identified as priority areas for implementing nitrogen reduction measures.	Nitrogen	182-190	NBL1, DAN family BMP antagonist	Homo sapiens	117-120
25193828-7	2014	For these "hot spot" areas DENUZ was used in a backward mode to quantify the maximal permissible nitrogen surplus levels in agriculture to guarantee a nitrate concentration in percolation water below 50mg NO3(-)/L.	Nitrogen	97-105	NBL1, DAN family BMP antagonist	Homo sapiens	205-208
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	epidermal growth factor receptor	Homo sapiens	176-180
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	tyrosinase related protein 1	Homo sapiens	234-238
25008051-0	2014	Excited state proton transfer of 2-(2"-hydroxyphenyl)benzimidazole and its nitrogen substituted analogues in bovine serum albumin.	Nitrogen	75-83	albumin	Homo sapiens	116-129
26877964-1	2014	BACKGROUND: N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propinoic acid (AMPA) receptors bound to postsynaptic density-95 (PSD-95) and alpha isoform of calcium/calmodulin-dependent protein kinase II (alphaCaMKII) is fundamentally involved in the regulation of working memory.	Nitrogen	12-14	DLG associated protein 2	Rattus norvegicus	127-150
26877964-1	2014	BACKGROUND: N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propinoic acid (AMPA) receptors bound to postsynaptic density-95 (PSD-95) and alpha isoform of calcium/calmodulin-dependent protein kinase II (alphaCaMKII) is fundamentally involved in the regulation of working memory.	Nitrogen	12-14	DLG associated protein 2	Rattus norvegicus	152-158
24990939-4	2014	We synthesized several panels of quaternary ammonium nAChR ligands that systematically varied the size of the substituents bonded to the central positively charged nitrogen atom.	Nitrogen	164-172	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	53-58
24985322-12	2014	We have, furthermore, mapped all N-linked glycosylations of CHO-expressed human sortilin by mass spectrometry and find that their locations are compatible with membrane insertion of the hydrophobic loops.	Nitrogen	33-34	sortilin 1	Homo sapiens	80-88
24998777-3	2014	TIMP-1 is an N-glycosylated protein that folds into two functional domains, a C- and an N-terminal domain, with six disulfide bonds.	Nitrogen	13-14	TIMP metallopeptidase inhibitor 1	Homo sapiens	0-6
24998777-6	2014	We describe here a HEK293 cell-based strategy for production and purification of secreted and N-glycosylated recombinant his6-tagged human TIMP-1 (his6-rTIMP-1), which resulted in large amounts of highly purified and bioactive protein.	Nitrogen	94-95	TIMP metallopeptidase inhibitor 1	Homo sapiens	139-145
25522608-9	2014	The contents of nitrate nitrogen in the root and leaves reached the highest at the NH4(+) -N/NO3(-) -N ratio of 50:50.	Nitrogen	24-32	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
24709669-8	2014	Increased levels of N- and O-glycosylated Apo A-I forms were found post-AMI.	Nitrogen	20-21	apolipoprotein A1	Homo sapiens	42-47
24709669-11	2014	Therefore, our results demonstrate that Apo A-I is both N- and O-glycosylated and that there is an increase in Apo A-I glycosylation after AMI.	Nitrogen	56-57	apolipoprotein A1	Homo sapiens	40-45
25135935-6	2014	Cotranslational N-glycosylation by the STT3A isoform of the OST, which lacks MagT1, allows efficient modification of acceptor sites in cysteine-rich protein domains before disulfide bond formation.	Nitrogen	16-17	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	60-63
25121773-2	2014	The predominant metabolic pathway of oxycodone is CYP3A4-mediated N-demethylation to noroxycodone, while a minor proportion undergoes 3-O-demethylation to oxymorphone by CYP2D6.	Nitrogen	66-67	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	50-56
25134574-1	2014	We investigate the formation of aqueous nitrogen dioxide, NO2 formed through femtosecond photolysis of nitrate, NO3- and nitromethane CH3NO2(aq).	Nitrogen	40-48	NBL1, DAN family BMP antagonist	Homo sapiens	112-115
24858219-1	2014	Water pollution in the form of nitrate nitrogen (NO3(-)-N) contamination is a major concern in most agricultural areas in the world.	Nitrogen	39-47	NBL1, DAN family BMP antagonist	Homo sapiens	49-52
24858219-4	2014	Approximately 46.7% of the surface water samples and 10% of the groundwater samples exceeded the World Health Organization (WHO) drinking water standard for NO3(-)-N.	Nitrogen	162-165	NBL1, DAN family BMP antagonist	Homo sapiens	157-160
25083110-8	2014	At 3, 6, 9, and 12 d of storage, volatile basic nitrogen values of MAP2 and MAP3 were higher (p&lt;0.05) than those of VP and MAP1.	Nitrogen	48-56	microtubule associated protein 2	Sus scrofa	67-71
25029371-7	2014	A strong correlation between cotranslational N-glycosylation efficiency and the rate of post-translational N-glycosylation was determined, showing that the OST STT3A and STT3B isoforms are similarly influenced by the hydroxyl and middle X consensus site residues.	Nitrogen	45-46	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	156-159
25083110-12	2014	It is concluded that the MAP containing 30:20:50/O2:CO2:N2 gas composition (MAP2) might be ideal for better meat quality for KNPxD meat.	Nitrogen	56-58	microtubule associated protein 2	Sus scrofa	76-80
25935996-6	2014	The simultaneous reduction and N-doping of GO using urine (denoted as UNG) have confirmed by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, and UV-vis spectroscopy.	Nitrogen	31-32	uracil DNA glycosylase	Homo sapiens	70-73
24760658-4	2014	In particular, joint analyses of observational data and outputs from the catchment model S-HYPE strengthened the evidence that downward trends in nitrogen were due to mitigation measures in agriculture.	Nitrogen	146-154	FIC domain protein adenylyltransferase	Homo sapiens	91-95
23914925-5	2014	Our results were compatible with experimental published data, showing feasible cation-pi interaction between the iron atom of the heme group of TXAS and the basic nitrogen atom of the imidazolyl group of those inhibitors.	Nitrogen	163-171	thromboxane A synthase 1	Homo sapiens	144-148
24337809-4	2014	However, all three type 2 BMP receptors (BMPR2, ACVR2A/B) contain consensus N-glycosylation sites in their extracellular domains (ECDs), which could play a role in modulating interaction with ligand.	Nitrogen	76-77	activin A receptor type 2A	Homo sapiens	48-56
24337809-5	2014	Here, we show a differential pattern of N-glycosylation between BMPR2 and ACVR2A/B.	Nitrogen	40-41	activin A receptor type 2A	Homo sapiens	74-82
24293102-7	2014	15-LOX and VDR are key neuromolecular factors essential in lipid-mediated signaling, neurotrophic support, defense against reactive oxygen and nitrogen species (reactive oxygen and nitrogen species), and neuroprotection in the CNS.	Nitrogen	143-151	arachidonate 15-lipoxygenase	Homo sapiens	0-6
24293102-7	2014	15-LOX and VDR are key neuromolecular factors essential in lipid-mediated signaling, neurotrophic support, defense against reactive oxygen and nitrogen species (reactive oxygen and nitrogen species), and neuroprotection in the CNS.	Nitrogen	181-189	arachidonate 15-lipoxygenase	Homo sapiens	0-6
25423832-4	2014	The drift tube temperature was 55 C, and nitrogen was used as carrier gas, with the flow rate of 2.0 L x min(-1) and gain of 1.0.	Nitrogen	41-49	CD59 molecule (CD59 blood group)	Homo sapiens	105-111
24895123-9	2014	These results are the first direct demonstration of the role of GOLPH3 in N-glycosylation to regulate cell biological functions.	Nitrogen	74-75	golgi phosphoprotein 3	Homo sapiens	64-70
25101106-1	2014	The dynamics of nitrate (NO(-) 3), a major nitrogen (N) source for natural plants, has been studied mostly through experimental N addition, enzymatic assay, isotope labeling, and genetic expression.	Nitrogen	43-51	NBL1, DAN family BMP antagonist	Homo sapiens	25-32
25002508-7	2014	In vitro biochemical studies show that G-CSF programs MPO-EL expression on human blood leukocytes and marrow myeloid cells via induction of N-linked sialofucosylations on MPO, with concomitant cell surface display of the molecule.	Nitrogen	140-141	myeloperoxidase	Homo sapiens	171-174
24964018-0	2014	Characterization of THB1, a Chlamydomonas reinhardtii truncated hemoglobin: linkage to nitrogen metabolism and identification of lysine as the distal heme ligand.	Nitrogen	87-95	uncharacterized protein	Chlamydomonas reinhardtii	20-24
24964018-6	2014	By using different C. reinhardtii strains and growth conditions, we demonstrate that the expression of THB1 is under the control of the NIT2 regulatory gene and that the hemoglobin is linked to the nitrogen assimilation pathway.	Nitrogen	198-206	uncharacterized protein	Chlamydomonas reinhardtii	103-107
24841887-7	2014	The obtained results indicate that the catalysis of levomepromazine 5-sulfoxidation and N-demethylation in humans shows a strict CYP3A4 preference, especially at a therapeutic drug concentration.	Nitrogen	88-89	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	129-135
24867957-0	2014	N-glycosylation is required for matriptase-2 autoactivation and ectodomain shedding.	Nitrogen	0-1	transmembrane serine protease 6	Homo sapiens	32-44
25000400-8	2014	Over the entire growing season, the soil nitrate N decreased by amounts ranging from 48.9 kg N ha-1 to 65.3 kg N ha-1 over the 90 cm profile and the loss of ammonia-N ranged from 9.79 to 12.69 kg N ha-1.	Nitrogen	49-50	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	95-99
25000400-8	2014	Over the entire growing season, the soil nitrate N decreased by amounts ranging from 48.9 kg N ha-1 to 65.3 kg N ha-1 over the 90 cm profile and the loss of ammonia-N ranged from 9.79 to 12.69 kg N ha-1.	Nitrogen	49-50	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	113-117
25000400-8	2014	Over the entire growing season, the soil nitrate N decreased by amounts ranging from 48.9 kg N ha-1 to 65.3 kg N ha-1 over the 90 cm profile and the loss of ammonia-N ranged from 9.79 to 12.69 kg N ha-1.	Nitrogen	49-50	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	113-117
24887412-8	2014	Treatments with either TNF-alpha antibodies or 2-APB also significantly improved the compromised GFR, elevated serum urea nitrogen and creatinine levels, and reversed the decrease in glomerular inulin space and the increase in glomerular calcium content in GalN/LPS-exposed rats.	Nitrogen	122-130	tumor necrosis factor	Rattus norvegicus	23-32
24742667-4	2014	DPAGT1 controls N-glycosylation of E-cadherin, the major epithelial cell-cell adhesion receptor and a tumor suppressor, thereby affecting intercellular adhesion and cytoskeletal dynamics.	Nitrogen	16-17	cadherin 1	Homo sapiens	35-45
24814977-9	2014	Treatment of mouse AML12 hepatocytes with the PPARbeta agonist (GW0742) decreased (14)C-18:2,n-6 in TGs but did not affect beta-oxidation.	Nitrogen	7-8	peroxisome proliferator activator receptor delta	Mus musculus	46-54
25210327-8	2014	Intake of sufu also increased the hepatic glycogen content, while it decreased the levels of both the blood lactic acid (BLA) and blood urea nitrogen (BUN) content.	Nitrogen	141-149	SUFU negative regulator of hedgehog signaling	Mus musculus	10-14
24790092-8	2014	Solution NMR analysis using (15)N-labeled ZG16p defined the heparin-binding region, which is on an adjacent flat surface of the protein.	Nitrogen	9-10	zymogen granule protein 16	Homo sapiens	42-47
24938787-1	2014	[URE3] is an amyloid prion of the Saccharomyces cerevisiae Ure2p, a regulator of nitrogen catabolism.	Nitrogen	81-89	glutathione peroxidase	Saccharomyces cerevisiae S288C	59-64
24888451-1	2014	Reaction of Co(II) with the nitrogen-rich ligand N,N-bis(1H-tetrazole-5-yl)-amine (H2bta) leads to a mixed-valence, 3D, porous, metal-organic framework (MOF)-based, energetic material with the nitrogen content of 51.78%, [Co9(bta)10(Hbta)2(H2O)10]n (22 H2O)n (1).	Nitrogen	28-36	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	12-18
24888451-1	2014	Reaction of Co(II) with the nitrogen-rich ligand N,N-bis(1H-tetrazole-5-yl)-amine (H2bta) leads to a mixed-valence, 3D, porous, metal-organic framework (MOF)-based, energetic material with the nitrogen content of 51.78%, [Co9(bta)10(Hbta)2(H2O)10]n (22 H2O)n (1).	Nitrogen	193-201	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	12-18
24947828-6	2014	The functions of the four validated genes, GCN1, MDS3, ARG81 and BIO3, relate to key roles in nitrogen metabolism and signaling, helping to maintain fermentation performance.	Nitrogen	94-102	adenosylmethionine-8-amino-7-oxononanoate transaminase	Saccharomyces cerevisiae S288C	65-69
24798337-2	2014	KDM6A (UTX) and KDM6B (JMJD3) are KDM6 subfamily members that catalyze demethylation of N(epsilon)-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression.	Nitrogen	88-89	lysine demethylase 6A	Homo sapiens	0-5
24798337-2	2014	KDM6A (UTX) and KDM6B (JMJD3) are KDM6 subfamily members that catalyze demethylation of N(epsilon)-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression.	Nitrogen	88-89	lysine demethylase 6A	Homo sapiens	7-10
24945938-6	2014	Treatment of ECs with tunicamycin, an N-glycosylation inhibitor, suppressed CD62P (P-selectin) expression on the cell surface as well as the 140 kDa form in the cytoplasm.	Nitrogen	38-39	selectin, platelet	Mus musculus	76-81
24945938-6	2014	Treatment of ECs with tunicamycin, an N-glycosylation inhibitor, suppressed CD62P (P-selectin) expression on the cell surface as well as the 140 kDa form in the cytoplasm.	Nitrogen	38-39	selectin, platelet	Mus musculus	83-93
24945938-7	2014	These results indicate that the 140 kDa band is N-glycosylated and glycosylation is critical for cell surface expression of P-selectin in ECs.	Nitrogen	48-49	selectin, platelet	Mus musculus	124-134
24947828-6	2014	The functions of the four validated genes, GCN1, MDS3, ARG81 and BIO3, relate to key roles in nitrogen metabolism and signaling, helping to maintain fermentation performance.	Nitrogen	94-102	Gcn1p	Saccharomyces cerevisiae S288C	43-47
24919067-7	2014	We show that the presence of a N-phenethyl group in position 17 is highly favorable in terms of improved affinity and selectivity at the MOP receptor, potent agonism and antinociceptive efficacy.	Nitrogen	31-32	opioid receptor, mu 1	Mus musculus	137-149
25158487-2	2014	The results showed that there were different forms of N transport by subsurface flow under different rainfall events, where in dissolved nitrogen (DN) accounted for about 53.74% - 99.21%, and nitrate (NO3(-) -N) accounted for about 35.70% - 93.65% of DN, and especially under the moderate rainfall, NO3(-) -N could reach 84.09% - 93.65% of DN.	Nitrogen	54-55	NBL1, DAN family BMP antagonist	Homo sapiens	201-204
26580767-3	2014	These alkanolamines are derivatives of MEA obtained by substitution with methyl and ethyl groups on the carbon atoms of the N-C-C-O backbone.	Nitrogen	124-125	male-enhanced antigen 1	Homo sapiens	39-42
24105419-4	2014	The plasma and pancreatic insulin and C-peptide levels and fecal cholesterol content were increased, whereas plasma urea nitrogen, free fatty acid and triglyceride levels were decreased by SK1 supplementation.	Nitrogen	121-129	skin antigen 1	Mus musculus	189-192
24590603-7	2014	Six nitrogen-cycling genes including chiA, amoA, nifH, nirK, nirS, and narG were quantified and found to decrease owing to both single- and multi-antibiotics perturbation.	Nitrogen	4-12	chitinase acidic	Homo sapiens	37-41
25158487-2	2014	The results showed that there were different forms of N transport by subsurface flow under different rainfall events, where in dissolved nitrogen (DN) accounted for about 53.74% - 99.21%, and nitrate (NO3(-) -N) accounted for about 35.70% - 93.65% of DN, and especially under the moderate rainfall, NO3(-) -N could reach 84.09% - 93.65% of DN.	Nitrogen	54-55	NBL1, DAN family BMP antagonist	Homo sapiens	299-302
25158487-3	2014	The different N fluxes were the highest under moderate rainfall among different rainfall events, in which the flux of total nitrogen (TN), DN, particle nitrogen (PN), ammonia (NH4(+) -N) and nitrite (NO2(-) -N) reached 737.17, 711.12, 26.06, 12.70 and 0.46 mg x m(-2), respectively, and the NO3(-)-N flux was as high as 686.12 mg x m(-2), showing a huge potential threat on groundwater health.	Nitrogen	14-15	NBL1, DAN family BMP antagonist	Homo sapiens	291-294
24607342-7	2014	Further analysis of the GP5 protein suggested that these strains of subgenotypes I, II and III exhibited variations in the primary neutralizing epitope and almost all isolates of subgenotypes II and III had more N-linked glycosylation sites.	Nitrogen	212-213	glycoprotein V platelet	Homo sapiens	24-27
24663342-0	2014	Ubiquitin ligase EL5 maintains the viability of root meristems by influencing cytokinin-mediated nitrogen effects in rice.	Nitrogen	97-105	epilepsy 5	Mus musculus	17-20
24663342-5	2014	The mEL5 mutants showed increased sensitivity to nitrogen that was reflected in the inhibition of root formation.	Nitrogen	49-57	epilepsy 5	Mus musculus	4-8
24663342-10	2014	These results indicate a nitrogen-triggered pathway that leads to changes in root formation through the production of cytokinin and superoxide, on which EL5 acts to prevent meristematic cell death.	Nitrogen	25-33	epilepsy 5	Mus musculus	153-156
24641951-9	2014	Administration of miR-204/miR-211 mimics substantially downregulated Hmx1 and mitigated the severity of the kidney injuries induced by Candidemia, as reflected by improved renal glomerular filtration rate (GFR) determined by serum cystatin C (CysC), serum beta2-microglobulin (beta2-MG) and blood urea nitrogen (BUN).	Nitrogen	302-310	microRNA 204	Mus musculus	18-25
24932134-3	2014	IL-6 receptor subunits are subject to N-glycosylation, a posttranslational modification which is important for protein stability and function.	Nitrogen	38-39	interleukin 6	Homo sapiens	0-4
24932134-4	2014	We speculated that the inhibition of STAT3 phosphorylation by glucosamine might be a functional consequence of the reduced N-glycosylation of gp130.	Nitrogen	123-124	signal transducer and activator of transcription 3	Homo sapiens	37-42
24733390-2	2014	The yeast homolog, Vps74p, interacts with and maintains the Golgi localization of several mannosyltransferases, which is subsequently critical for N- and O-glycosylation in yeast.	Nitrogen	147-148	Vps74p	Saccharomyces cerevisiae S288C	19-25
24644239-2	2014	Originally, CCL1 was identified as a 73 amino acid protein having one N-glycosylation site, and a variant 74 residue non-glycosylated form, Ser-CCL1, has also been described.	Nitrogen	70-71	C-C motif chemokine ligand 1	Homo sapiens	12-16
24644271-3	2014	During nitrogen excess, the transcription activators are sequestered in the cytoplasm in a Ure2-dependent fashion.	Nitrogen	7-15	glutathione peroxidase	Saccharomyces cerevisiae S288C	91-95
25505590-5	2014	CYP3A isoforms mostly contributed to N-debutylation while hydroxylation on the butyl-benzofuran moiety was catalyzed by CYP2D6.	Nitrogen	37-38	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-5
24692304-3	2014	We used glycosylated Ser-CCL1 that had been prepared by total chemical synthesis as a homogeneous compound containing an N-linked asialo biantennary nonasaccharide glycan moiety of defined covalent structure.	Nitrogen	121-122	C-C motif chemokine ligand 1	Homo sapiens	25-29
25199249-7	2014	RESULTS &amp; CONCLUSION: We obtained a delta och1 delta alg3 delta mnn1 strain that produces Man5 GlcNAc2 intermediate of human N-glycosylation.	Nitrogen	16-17	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	68-72
24641951-9	2014	Administration of miR-204/miR-211 mimics substantially downregulated Hmx1 and mitigated the severity of the kidney injuries induced by Candidemia, as reflected by improved renal glomerular filtration rate (GFR) determined by serum cystatin C (CysC), serum beta2-microglobulin (beta2-MG) and blood urea nitrogen (BUN).	Nitrogen	302-310	microRNA 211	Mus musculus	26-33
23837490-8	2014	Nitrogen isotopic ratios (delta(15) N) increase markedly, ranging from +3.5 to &gt; +50, and correlate inversely with NO3 -N concentrations.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	118-121
24720891-0	2014	RCAN1 increases Abeta generation by promoting N-glycosylation via oligosaccharyltransferase.	Nitrogen	3-4	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	66-91
24720891-2	2014	N-glycosylation in ER is mediated by oligosaccharyltransferase (OST), an enzyme complex transferring preassembled oligosaccharide to asparagine residues of nascent polypeptide chain.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	37-62
24720891-2	2014	N-glycosylation in ER is mediated by oligosaccharyltransferase (OST), an enzyme complex transferring preassembled oligosaccharide to asparagine residues of nascent polypeptide chain.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	64-67
24561278-4	2014	New complexes of palladium (II), with general formulae [Pd(PPh3)2(L)]PF6 or [PdCl(PPh3)(L)], where L=N,N-disubstituted-N"-acyl thioureas, were synthesized and characterized by elemental analysis, molar conductivity, melting points, IR, NMR((1)H, (13)C and (31)P{(1)H}) spectroscopy.	Nitrogen	0-1	caveolin 1	Homo sapiens	59-63
24549892-5	2014	As the test case we chose ABCA4, a large integral membrane protein with 16 predicted sites for N-glycosylation.	Nitrogen	95-96	ATP binding cassette subfamily A member 4	Homo sapiens	26-31
24561278-4	2014	New complexes of palladium (II), with general formulae [Pd(PPh3)2(L)]PF6 or [PdCl(PPh3)(L)], where L=N,N-disubstituted-N"-acyl thioureas, were synthesized and characterized by elemental analysis, molar conductivity, melting points, IR, NMR((1)H, (13)C and (31)P{(1)H}) spectroscopy.	Nitrogen	0-1	caveolin 1	Homo sapiens	82-86
24697594-17	2014	The Tpa* ligand binds the Cu center to three of its four N atoms, with one pyrazolyl arm remaining uncoordinated.	Nitrogen	57-58	plasminogen activator, tissue type	Homo sapiens	4-8
24554659-0	2014	Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.	Nitrogen	20-21	CD4 molecule	Homo sapiens	159-162
24816694-7	2014	As calculated from the regression equation, the ED50 (ecological dose) values of activities of soil urease, invertase and catalase were around 800mg/kg; the ED50 values of soil sulfate-reducing activity, methanogen activity and anaerobic nitrogen-fixing activity were also around 800mg/kg with an exception of soil denitrifying activity which ranged 35 to 39 mg/kg.	Nitrogen	238-246	catalase	Homo sapiens	122-130
25151725-1	2014	Aldehyde oxidase (AOX), a highly conserved molybdoflavoenzyme in mammal cytoplasm, has broad substrate specificity and ability to catalyze the oxidation of aldehydes and nitrogen, oxygen-containing heterocyclic rings.	Nitrogen	170-178	aldehyde oxidase 1	Homo sapiens	0-16
25151725-1	2014	Aldehyde oxidase (AOX), a highly conserved molybdoflavoenzyme in mammal cytoplasm, has broad substrate specificity and ability to catalyze the oxidation of aldehydes and nitrogen, oxygen-containing heterocyclic rings.	Nitrogen	170-178	aldehyde oxidase 1	Homo sapiens	18-21
24738575-4	2014	By exposing Pd powder to dilute hydrogen in nitrogen gas, sacrificial surface PdH is formed along with a controlled amount of dilute interstitial hydride.	Nitrogen	44-52	pyruvate dehydrogenase phosphatase catalytic subunit 1	Homo sapiens	78-81
24657054-5	2014	The SAR reported here is focused on the influence of various piperidine nitrogen aromatic substituents on the ratio of binding affinity and intrinsic activity at both the NOP and MOP receptors.	Nitrogen	72-80	prepronociceptin	Homo sapiens	171-174
25395735-4	2014	Voltammetry experiments revealed that this system displays a rich redox chemistry under N2, as [Re(BB2)(CO)3Cl] can be reduced by up to four electrons at modest potentials.	Nitrogen	88-90	gastrin releasing peptide receptor	Homo sapiens	99-102
25371572-10	2014	The data obtained showed that PGP could extend the exhaustive swimming time of the rats, as well as decrease the blood lactic acid (BLA), and blood urea nitrogen (BUN), concentrations, and increase the hemoglobin, liver glycogen and muscle glycogen concentrations.	Nitrogen	153-161	phosphoglycolate phosphatase	Rattus norvegicus	30-33
24685145-1	2014	N-linked glycosylation of proteins in the endoplasmic reticulum (ER) is essential in eukaryotes and catalyzed by oligosaccharyl transferase (OST).	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	141-144
24164541-1	2014	Aerosolized exposure to the chemical warfare vesicant sulfur mustard and its analog nitrogen mustard (HN2) is known to induce airway lesions associated with secretion of proinflammatory cytokines such as IL-6.	Nitrogen	84-92	interleukin 6	Homo sapiens	204-208
24037975-1	2014	The metal-dependent deacetylase N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) catalyzes the deacetylation of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins), the committed step in mycothiol (MSH) biosynthesis.	Nitrogen	32-34	msh homeobox 2	Homo sapiens	261-264
24368523-3	2014	Most vitamins synthesized by plants present amino acids as precursors (B1, B2, B3, B5, B7, B9 and E) and are therefore linked to plant nitrogen metabolism.	Nitrogen	135-143	immunoglobulin kappa variable 7-3 (pseudogene)	Homo sapiens	71-99
24566535-5	2014	Under carbon- and nitrogen-starved conditions, the number and size of vesicles labeled by GFP-ATG8 was increased for several hours and then gradually decreased to a level higher than that observed before the start of the experiment.	Nitrogen	18-26	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	94-98
24744735-3	2014	The physiological function of FACs is presumably to enhance nitrogen assimilation in Spodoptera litura larvae, but in other insects it is totally unknown.	Nitrogen	60-68	Acyl-CoA synthetase long-chain	Drosophila melanogaster	30-34
24633771-4	2014	The conserved hydrophobic adenine region of PI3Kalpha made up of Met772, Pro778, Ile800, Tyr836, Ile848, Val850, Val851, Met922, Phe930 and Ile932 accommodates the flat 2-tert-butyl-4"-methyl-4,5"-bithiazol moiety of A-66S, and the NH of Val851 forms a hydrogen with the nitrogen atom embedded in the aminothiazole ring of A-66S.	Nitrogen	271-279	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Homo sapiens	44-53
24468271-1	2014	Secretory human interleukin 4 (hIL4) is an N-glycosylated pleiotropic cytokine.	Nitrogen	43-44	interleukin 4	Homo sapiens	16-29
24468271-4	2014	Using the site-directed mutagenesis technique, we made two mutant hIL4 cDNA clones (N38A and N105L) and subsequently expressed them in P. pastoris to analyze the relevant function of each N-glycosylation site on hIL4.	Nitrogen	73-74	interleukin 4	Homo sapiens	66-70
24468271-1	2014	Secretory human interleukin 4 (hIL4) is an N-glycosylated pleiotropic cytokine.	Nitrogen	43-44	interleukin 4	Homo sapiens	31-35
24490900-0	2014	Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.	Nitrogen	0-8	thymoma viral proto-oncogene 1	Mus musculus	127-130
24515114-11	2014	Blood urea nitrogen and creatinine values tended to be lower after inhibiting RAGE.	Nitrogen	11-19	advanced glycosylation end product-specific receptor	Mus musculus	78-82
24299984-4	2014	The mechanism of binding of Na2[M(L)(H2O)n] with human serum albumin (HSA) was studied by fluorescence spectroscopic technique.	Nitrogen	9-10	albumin	Homo sapiens	55-68
24422467-3	2014	In this work, we designed and synthesized two novel classes of tri- and tetracyclic nitrogen-bridgehead compounds acting as dual AChE inhibitors and histamine H3 antagonists by combining the nitrogen-bridgehead moiety of novel AChE inhibitors with a second N-basic fragment based on the piperidinylpropoxy pharmacophore with different spacer lengths.	Nitrogen	191-199	acetylcholinesterase (Cartwright blood group)	Homo sapiens	129-133
24422467-3	2014	In this work, we designed and synthesized two novel classes of tri- and tetracyclic nitrogen-bridgehead compounds acting as dual AChE inhibitors and histamine H3 antagonists by combining the nitrogen-bridgehead moiety of novel AChE inhibitors with a second N-basic fragment based on the piperidinylpropoxy pharmacophore with different spacer lengths.	Nitrogen	191-199	acetylcholinesterase (Cartwright blood group)	Homo sapiens	227-231
24471499-5	2014	Pathway analysis of cancer-associated aberrant glycoproteins revealed an emerging phenomenon that increased activity of N-glycosylation was implicated in several pancreatic cancer pathways, including TGF-beta, TNF, NF-kappa-B, and TFEB-related lysosomal changes.	Nitrogen	120-121	tumor necrosis factor	Homo sapiens	210-213
24471499-5	2014	Pathway analysis of cancer-associated aberrant glycoproteins revealed an emerging phenomenon that increased activity of N-glycosylation was implicated in several pancreatic cancer pathways, including TGF-beta, TNF, NF-kappa-B, and TFEB-related lysosomal changes.	Nitrogen	120-121	nuclear factor kappa B subunit 1	Homo sapiens	215-225
24594013-5	2014	Moreover, when expressed in human embryonic kidney 293 cells, N-glycosylated AChE co-immunoprecipitated with non-O-glycosylated neurexin-1beta, with N-glycosylation of the AChE being required for this co-precipitation to occur.	Nitrogen	62-63	acetylcholinesterase (Cartwright blood group)	Homo sapiens	77-81
24594013-5	2014	Moreover, when expressed in human embryonic kidney 293 cells, N-glycosylated AChE co-immunoprecipitated with non-O-glycosylated neurexin-1beta, with N-glycosylation of the AChE being required for this co-precipitation to occur.	Nitrogen	62-63	acetylcholinesterase (Cartwright blood group)	Homo sapiens	172-176
24594013-5	2014	Moreover, when expressed in human embryonic kidney 293 cells, N-glycosylated AChE co-immunoprecipitated with non-O-glycosylated neurexin-1beta, with N-glycosylation of the AChE being required for this co-precipitation to occur.	Nitrogen	149-150	acetylcholinesterase (Cartwright blood group)	Homo sapiens	77-81
24584735-0	2014	Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.	Nitrogen	33-34	ATP binding cassette subfamily G member 5	Homo sapiens	83-88
24091465-4	2014	The second outcome was the nitrogen phase III slope (SN2), an index of global ventilation heterogeneity derived from the tidal nitrogen SBW test using pure oxygen.	Nitrogen	27-35	solute carrier family 38 member 5	Homo sapiens	53-56
24091465-4	2014	The second outcome was the nitrogen phase III slope (SN2), an index of global ventilation heterogeneity derived from the tidal nitrogen SBW test using pure oxygen.	Nitrogen	127-135	solute carrier family 38 member 5	Homo sapiens	53-56
24492544-13	2014	Increases in log fly count were associated with decreases (P &lt; 0.05) in milk fat, solids-not-fat, and milk urea nitrogen.	Nitrogen	115-123	Weaning weight-maternal milk	Bos taurus	105-109
24135452-9	2014	The ABCB1-dependent ATPase activity stimulated by nitensidine A was greatly reduced by substituting sulfur (S) or oxygen (O) for the imino nitrogen atom (N) in nitensidine A.	Nitrogen	139-147	ATP binding cassette subfamily B member 1	Homo sapiens	4-9
24135452-13	2014	The present results also suggest that the number, binding site, and polymerization degree of the isoprenyl moiety in the guanidine alkaloids and the imino nitrogen atom cooperatively contribute to their stimulation of ABCB1"s ATPase activity.	Nitrogen	155-163	ATP binding cassette subfamily B member 1	Homo sapiens	218-223
24860196-2	2014	In adsorption experiments, the novel amine-PIM-1 showed higher CO2 uptake and higher CO2/N2 sorption selectivity than the parent polymer, with very evident dual-mode sorption behavior.	Nitrogen	89-91	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	43-48
24308486-0	2014	Site-specific N-glycosylation analysis of human immunoglobulin e.	Nitrogen	14-15	immunoglobulin heavy constant epsilon	Homo sapiens	48-64
24010633-11	2014	The major metabolites of metoclopramide were N-hydroxylation and N-deethylation formed most efficiently by CYP2D6 but also formed by all CYPs examined.	Nitrogen	45-46	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	107-113
24010633-11	2014	The major metabolites of metoclopramide were N-hydroxylation and N-deethylation formed most efficiently by CYP2D6 but also formed by all CYPs examined.	Nitrogen	65-66	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	107-113
24663680-6	2014	Experiments using tunicamycin, an inhibitor of N-glycosylation, indicated that the N-glycosylation of hKv1.5 is more effective at 28 C than at 37 C. Finally, the hypothermic treatment also rescued the protein expression and currents of trafficking-defective hKv1.5 mutants.	Nitrogen	47-48	potassium voltage-gated channel subfamily A member 5	Homo sapiens	102-108
24663680-6	2014	Experiments using tunicamycin, an inhibitor of N-glycosylation, indicated that the N-glycosylation of hKv1.5 is more effective at 28 C than at 37 C. Finally, the hypothermic treatment also rescued the protein expression and currents of trafficking-defective hKv1.5 mutants.	Nitrogen	83-84	potassium voltage-gated channel subfamily A member 5	Homo sapiens	102-108
24663680-6	2014	Experiments using tunicamycin, an inhibitor of N-glycosylation, indicated that the N-glycosylation of hKv1.5 is more effective at 28 C than at 37 C. Finally, the hypothermic treatment also rescued the protein expression and currents of trafficking-defective hKv1.5 mutants.	Nitrogen	83-84	potassium voltage-gated channel subfamily A member 5	Homo sapiens	258-264
24519942-2	2014	Protein translocation across the ER membrane and N-glycosylation are highly coordinated processes that take place at the translocon-oligosaccharyltransferase (OST) complex.	Nitrogen	49-50	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	121-157
24519942-2	2014	Protein translocation across the ER membrane and N-glycosylation are highly coordinated processes that take place at the translocon-oligosaccharyltransferase (OST) complex.	Nitrogen	49-50	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	159-162
24519942-6	2014	The coordinated interplay between PMTs and OST in vivo is further shown by a comprehensive mass spectrometry-based analysis of N-glycosylation site occupancy in pmtDelta mutants.	Nitrogen	127-128	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	43-46
24422467-0	2014	Synthesis, biological evaluation, and computational studies of Tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.	Nitrogen	84-92	acetylcholinesterase (Cartwright blood group)	Homo sapiens	136-140
24422467-3	2014	In this work, we designed and synthesized two novel classes of tri- and tetracyclic nitrogen-bridgehead compounds acting as dual AChE inhibitors and histamine H3 antagonists by combining the nitrogen-bridgehead moiety of novel AChE inhibitors with a second N-basic fragment based on the piperidinylpropoxy pharmacophore with different spacer lengths.	Nitrogen	84-92	acetylcholinesterase (Cartwright blood group)	Homo sapiens	129-133
24422467-3	2014	In this work, we designed and synthesized two novel classes of tri- and tetracyclic nitrogen-bridgehead compounds acting as dual AChE inhibitors and histamine H3 antagonists by combining the nitrogen-bridgehead moiety of novel AChE inhibitors with a second N-basic fragment based on the piperidinylpropoxy pharmacophore with different spacer lengths.	Nitrogen	84-92	acetylcholinesterase (Cartwright blood group)	Homo sapiens	227-231
24607031-8	2014	NF-kappaB p65 levels in urinary sediment cells showed a significant positive correlation with serum Cr (Day 0: rs=0.792; p &lt;0.001, Day 7: rs=0.605; p &lt;0.001) and blood urea nitrogen (BUN) (Day 0: rs=0.839; p &lt;0.001, Day 7: rs=0.596; p &lt;0.001).	Nitrogen	179-187	nuclear factor kappa B subunit 1	Homo sapiens	0-9
24594722-4	2014	Each 2,5-PDC(2-) anion chelates to one Co(II) cation via the pyridine N atom and an O atom of the adjacent carboxylate group, and links to two other Co(II) cations in a bridging mode via the O atoms of the other carboxylate group.	Nitrogen	70-71	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	39-45
23984829-11	2014	Path analysis indicated that number of atoms, oxygen &amp; nitrogen atoms, and Log P are the greatest determinants for formula weight for known COX-2 inhibitors.	Nitrogen	59-67	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	144-149
24302597-0	2014	A comparative study of in vitro cytotoxic, antioxidant, and antimicrobial activity of Pt(II), Zn(II), Cu(II), and Co(III) complexes with N-heteroaromatic Schiff base (E)-2-[N"-(1-pyridin-2-yl-ethylidene)hydrazino]acetate.	Nitrogen	137-138	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	117-120
24334254-8	2014	This is clearly illustrated by the differences in copy numbers not only in gene PUT1, the main player in the assimilation of proline as a nitrogen source, but also in CAR2, involved in arginine catabolism.	Nitrogen	138-146	proline dehydrogenase	Saccharomyces cerevisiae S288C	80-84
24324255-0	2014	Constitutive and nitrogen catabolite repression-sensitive production of Gat1 isoforms.	Nitrogen	17-25	solute carrier family 6 member 1	Homo sapiens	72-76
24791412-0	2014	Conformational study of N-methylated alanine peptides and design of Abeta inhibitor.	Nitrogen	24-25	amyloid beta precursor protein	Homo sapiens	68-73
24791412-6	2014	Conformational behavior of peptides containing N-MeAla and Ala was used to design Abeta peptide inhibitor and the model tetrapeptide Ac-Ala-NMeAla-Ala-NHMe in the beta-strand structure was shown to interact with the hydrophobic stretch of Abeta15-42 peptide.	Nitrogen	47-48	amyloid beta precursor protein	Homo sapiens	82-87
24342685-9	2014	Milk protein percentage and yield and lactose yield were increased and milk urea nitrogen was decreased for NS compared with RS.	Nitrogen	81-89	Weaning weight-maternal milk	Bos taurus	71-75
24325456-3	2014	The results showed that N-CMCh nanoparticle enhanced the secretion of cytokines (interleukin [IL]-6, IL-12p70, and tumor necrosis factor-alpha) and antigen uptake in bone marrow-derived dendritic cells.	Nitrogen	24-25	tumor necrosis factor	Mus musculus	115-142
24367020-8	2014	By contrast, the AOP2 transcript level was negatively correlated with miR826 and miR5090 under nitrogen starvation.	Nitrogen	95-103	AOP2	Arabidopsis thaliana	17-21
24369314-0	2014	Immunotherapeutic potential of N-formylated peptides of ESAT-6 and glutamine synthetase in experimental tuberculosis.	Nitrogen	31-32	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	67-87
24324255-1	2014	Nitrogen catabolite repression (NCR)-sensitive transcription is activated by Gln3 and Gat1.	Nitrogen	0-8	solute carrier family 6 member 1	Homo sapiens	86-90
24324255-2	2014	In nitrogen excess, Gln3 and Gat1 are cytoplasmic, and transcription is minimal.	Nitrogen	3-11	solute carrier family 6 member 1	Homo sapiens	29-33
24324255-3	2014	In poor nitrogen, Gln3 and Gat1 become nuclear and activate transcription.	Nitrogen	8-16	solute carrier family 6 member 1	Homo sapiens	27-31
24489966-8	2014	Furthermore, serum CXCL16 concentration negatively correlated with estimated glomerular filtrate rate, creatinine clearance rate and blood albumin, and positively with 24 h proteinuria, blood urea nitrogen (BUN), creatinine, and uric acid after adjusting for age, gender and BMI in subjects with DN.	Nitrogen	197-205	C-X-C motif chemokine ligand 16	Homo sapiens	19-25
24900832-0	2014	Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning.	Nitrogen	67-75	mitogen-activated protein kinase kinase 7	Homo sapiens	49-52
24900832-2	2014	The impact after nitrogen substitution on interactions between a derivative and its on- and off-target proteins (Raf/MEK, CYPs, and hERG channel) was also detected, most of them contributing to weaker interactions.	Nitrogen	17-25	mitogen-activated protein kinase kinase 7	Homo sapiens	117-120
24900832-2	2014	The impact after nitrogen substitution on interactions between a derivative and its on- and off-target proteins (Raf/MEK, CYPs, and hERG channel) was also detected, most of them contributing to weaker interactions.	Nitrogen	17-25	ETS transcription factor ERG	Homo sapiens	132-136
23875749-0	2014	Interaction of inducible nitric oxide synthase with rac2 regulates reactive oxygen and nitrogen species generation in the human neutrophil phagosomes: implication in microbial killing.	Nitrogen	87-95	nitric oxide synthase 2	Homo sapiens	15-46
24485462-5	2014	Specifically, the nitrogen mustard cyclophosphamide induces an acute secretory activating phenotype (ASAP), releasing CCL4, IL8, VEGF, and TNFalpha from treated tumor cells.	Nitrogen	18-26	C-X-C motif chemokine ligand 8	Homo sapiens	124-127
24485462-5	2014	Specifically, the nitrogen mustard cyclophosphamide induces an acute secretory activating phenotype (ASAP), releasing CCL4, IL8, VEGF, and TNFalpha from treated tumor cells.	Nitrogen	18-26	vascular endothelial growth factor A	Homo sapiens	129-133
24485462-5	2014	Specifically, the nitrogen mustard cyclophosphamide induces an acute secretory activating phenotype (ASAP), releasing CCL4, IL8, VEGF, and TNFalpha from treated tumor cells.	Nitrogen	18-26	tumor necrosis factor	Homo sapiens	139-147
24196659-4	2014	The two amine-modified MIL-101Cr-NH2 (4) and MIL-101Cr-pNH2 (5) showed the highest gas uptake capacities in the series with high ratios for the CO2 : N2 and CO2 : CH4 selectivities (up to 119 : 1 and 75 : 1, respectively, at 273 K).	Nitrogen	150-152	phosphatidylinositol glycan anchor biosynthesis class T	Homo sapiens	55-59
23875749-0	2014	Interaction of inducible nitric oxide synthase with rac2 regulates reactive oxygen and nitrogen species generation in the human neutrophil phagosomes: implication in microbial killing.	Nitrogen	87-95	Rac family small GTPase 2	Homo sapiens	52-56
24435307-4	2014	We provide evidence that TUSC3 is part of the OST complex and affects N-linked glycosylation in mammalian cells.	Nitrogen	70-71	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	46-49
27493492-4	2014	We validated the sensitivity of this method using bathorhodopsin, a photoproduct of rhodopsin trapped at liquid nitrogen temperature, which undergoes little conformational changes from the dark state as shown by the X-ray crystallography.	Nitrogen	112-120	rhodopsin	Homo sapiens	55-64
24466071-3	2014	Hepatic arterial infusion of the vasoconstrictor angiotensin II (AT-II) is reported to increase the T/N blood flow ratio.	Nitrogen	102-103	angiotensinogen	Homo sapiens	49-63
24466071-3	2014	Hepatic arterial infusion of the vasoconstrictor angiotensin II (AT-II) is reported to increase the T/N blood flow ratio.	Nitrogen	102-103	angiotensinogen	Homo sapiens	65-70
24466071-14	2014	CONCLUSIONS: Infusion of AT-II into the hepatic artery leads to an increase of the tumor to non-tumor blood flow ratio, as measured by T/N uptake ratios.	Nitrogen	2-3	angiotensinogen	Homo sapiens	25-30
24292153-6	2014	N-Hcy-Lys562, N-Hcy-Lys344, and N-Hcy-Lys385 were identified in human fibrinogen from patients with cystathionine beta-synthase deficiency.	Nitrogen	0-1	fibrinogen beta chain	Homo sapiens	70-80
24328044-5	2014	Among all samples analyzed, the composite of Cu-BTC and modified graphite oxide with the highest N content (MOF/GO-U3) is the best performing sample.	Nitrogen	97-98	betacellulin	Homo sapiens	48-51
24120669-6	2014	Notably, risedronate, a nitrogen-containing bisphosphonate widely used in the treatment of osteoporosis, induced the expression and secretion of progranulin in the Hobit secretome.	Nitrogen	24-32	granulin precursor	Homo sapiens	145-156
25057492-4	2014	Mannosylated chitosan ODN nanoparticles (MCHODN NPs) were formulated by self-assembled method using various N/P ratio (moles of amine groups of MCH to phosphate moieties of ODNs) and characterized for gel retardation assay, physicochemical characteristics, cytotoxicity and transfection efficiency, and antisense assay.	Nitrogen	24-25	pro-melanin concentrating hormone	Homo sapiens	41-44
25057492-6	2014	On increasing the N/P ratio of MCH/ODN, particle size of the NPs decreased whereas zeta potential (ZV) increased.	Nitrogen	18-19	pro-melanin concentrating hormone	Homo sapiens	31-34
23836015-5	2014	ALD3 deletion strain overexpressing ARO9 and ARO10 both by episomal overexpression and by induction of the endogenous genes through overexpression of Aro80 transcription factor, produced 4.8 g/L 2-PE in a medium containing 10 g/L L-phenylalanine as a sole nitrogen source.	Nitrogen	256-264	aldehyde dehydrogenase (NAD(+)) ALD3	Saccharomyces cerevisiae S288C	0-4
24982916-11	2014	N-3 supplementation did not attenuate the negative effects of dexamethasone on skeletal muscle; instead, it caused atrophy in type 1, 2A, reduced the expression of Myogenin, and increased the expression of Atrogin-1.	Nitrogen	0-1	F-box protein 32	Rattus norvegicus	206-215
24369116-4	2014	Our results show considerable differences in H43R compared to WT and W32F mutated SOD1, such as increasing distances between the critical residues results in open conformation at the active site, strong fluctuations in the important loops (Zinc and electrostatic loops) and weakening of important hydrogen bonds especially between N (His 43/Arg 43) and carbonyl oxygen (His 120) in agreement with the experimental report.	Nitrogen	331-332	superoxide dismutase 1	Homo sapiens	82-86
23753222-7	2014	CONCLUSIONS: Hyperchloremia resulting in nonanion gap acidosis can occur and may prolong the duration of insulin infusion and length of PICU stay in patients receiving NS as post-bolus rehydration fluid.	Nitrogen	9-11	insulin	Homo sapiens	105-112
24381864-17	2014	We found that erythropoietin was able to prevent the increase in serum creatinine and blood urea nitrogen.	Nitrogen	97-105	erythropoietin	Homo sapiens	14-28
24437448-5	2014	Under the same conditions, the SO2 adsorption capacity of PME-supported modified PEI and G3 was significantly higher, reaching 4.68 and 4.34 mmol/g, corresponding to SO2/N ratios of 0.41 and 0.82, respectively.	Nitrogen	170-171	cystatin B	Homo sapiens	58-61
24372221-5	2014	The prolonged oxidative stress and the resultant hypoperfusion in the brain tissues stimulate the expression of nitric oxide synthase (NOS) enzymes, which further drives the formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS).	Nitrogen	230-238	nitric oxide synthase 2	Homo sapiens	112-133
24850316-5	2014	In HLM, the dehalogenated metabolite accounts for about 87% of the full 1 metabolism, while the N-dealkylated metabolite accounts for 12%.	Nitrogen	96-97	oxysterol binding protein 2	Homo sapiens	3-6
25343291-0	2014	Enantioselective N-demethylation and hydroxylation of sibutramine in human liver microsomes and recombinant cytochrome p-450 isoforms.	Nitrogen	17-18	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	108-124
24415948-3	2014	We find that rapid adaptive evolution in nitrogen-poor environments is dominated by the de novo generation and selection of copy number variants (CNVs), a large fraction of which contain genes encoding specific nitrogen transporters including PUT4, DUR3 and DAL4.	Nitrogen	41-49	Dur3p	Saccharomyces cerevisiae S288C	249-253
24567814-7	2014	RESULTS: In comparison to the control group, the NP + NS group showed a significant increase of phospho-p38 and p38 MAPK, as well as of the proinflammatory cytokines, tumor necrosis factor alpha (TNFalpha), and intercellular adhesion molecule 1 (ICAM1).	Nitrogen	54-56	tumor necrosis factor	Rattus norvegicus	167-194
24567814-7	2014	RESULTS: In comparison to the control group, the NP + NS group showed a significant increase of phospho-p38 and p38 MAPK, as well as of the proinflammatory cytokines, tumor necrosis factor alpha (TNFalpha), and intercellular adhesion molecule 1 (ICAM1).	Nitrogen	54-56	tumor necrosis factor	Rattus norvegicus	196-204
25019053-1	2014	Congenital Disorder of Glycosylation type Ig (ALG12-CDG) is part of a group of autosomal recessive conditions caused by deficiency of proteins involved in the assembly of dolichol-oligosaccharides used for protein N-glycosylation.	Nitrogen	214-215	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	46-51
24476960-5	2014	Under poor nitrogen supply, Npr1 enables Mep2 S457 phosphorylation and thus ammonium transport activity.	Nitrogen	11-19	natriuretic peptide receptor 1	Homo sapiens	28-32
24476960-6	2014	Supplementation of the preferred nitrogen source glutamine leads to Mep2 inactivation and instant S457 dephosphorylation via plasma membrane Psr1 and Psr2 redundant phosphatases.	Nitrogen	33-41	CTD small phosphatase like	Homo sapiens	141-145
24476960-6	2014	Supplementation of the preferred nitrogen source glutamine leads to Mep2 inactivation and instant S457 dephosphorylation via plasma membrane Psr1 and Psr2 redundant phosphatases.	Nitrogen	33-41	CTD small phosphatase 2	Homo sapiens	150-154
24943989-1	2014	BACKGROUND AND AIMS: N-truncated pyroglutamate (pGlu)-amyloid-beta [Abeta(3-40/42)] peptides are key components that promote Abeta peptide accumulation, leading to neurodegeneration and memory loss in Alzheimer"s disease.	Nitrogen	8-9	amyloid beta precursor protein	Homo sapiens	68-73
24943989-1	2014	BACKGROUND AND AIMS: N-truncated pyroglutamate (pGlu)-amyloid-beta [Abeta(3-40/42)] peptides are key components that promote Abeta peptide accumulation, leading to neurodegeneration and memory loss in Alzheimer"s disease.	Nitrogen	8-9	amyloid beta precursor protein	Homo sapiens	125-130
24275315-6	2014	Detoxification through N-acetylation was further confirmed by comparing PPD, DAT and AHT in the Comet assay using standard V79 cells (N-acetyltransferase (NAT) deficient) and two NAT-proficient cell lines,V79NAT1*4 and HaCaT (human keratinocytes).	Nitrogen	23-24	arylamine N-acetyltransferase 2	Cricetulus griseus	155-158
24164597-6	2014	The rel3 mutant produced fewer pink nitrogen-fixing nodules, with substantially decreased infection frequency and nodule initiation.	Nitrogen	36-44	REL3	Lotus japonicus	4-8
25495764-2	2014	Studies showed that recombinant cellular PrP, PrP(C), expressed in Escherichia coli lacks N-glycosylation and an glycophosphatidyl inositol anchor (GPI) and therefore may not be the most suitable substrate in seeded PMCA reactions to recapitulate prion conversion in vitro.	Nitrogen	90-91	prion protein	Homo sapiens	46-52
23824663-2	2014	Proline-fueled mitochondrial metabolism involves the oxidative conversion of L-Proline to L-Glutamate in two enzymatic steps by means of Put1p and Put2p that help Saccharomyces cerevisiae to respond to changes in the nutritional environment by initiating the breakdown of L-Proline as a source for nitrogen, carbon, and energy.	Nitrogen	298-306	proline dehydrogenase	Saccharomyces cerevisiae S288C	137-142
24977238-7	2014	The average monthly attribution rate of atmospheric deposition of NO3 (-)-N and NH4 (+)-N was ~31.38% and ~20.50% for the contents of NO3 (-)-N and NH4 (+)-N in 0-10 cm soil layer, respectively, suggested that the atmospheric nitrogen was one of main sources for soil nitrogen in coastal zone of the YRD.	Nitrogen	226-234	NBL1, DAN family BMP antagonist	Homo sapiens	66-69
24977238-7	2014	The average monthly attribution rate of atmospheric deposition of NO3 (-)-N and NH4 (+)-N was ~31.38% and ~20.50% for the contents of NO3 (-)-N and NH4 (+)-N in 0-10 cm soil layer, respectively, suggested that the atmospheric nitrogen was one of main sources for soil nitrogen in coastal zone of the YRD.	Nitrogen	226-234	NBL1, DAN family BMP antagonist	Homo sapiens	134-137
24977238-7	2014	The average monthly attribution rate of atmospheric deposition of NO3 (-)-N and NH4 (+)-N was ~31.38% and ~20.50% for the contents of NO3 (-)-N and NH4 (+)-N in 0-10 cm soil layer, respectively, suggested that the atmospheric nitrogen was one of main sources for soil nitrogen in coastal zone of the YRD.	Nitrogen	268-276	NBL1, DAN family BMP antagonist	Homo sapiens	66-69
24977238-7	2014	The average monthly attribution rate of atmospheric deposition of NO3 (-)-N and NH4 (+)-N was ~31.38% and ~20.50% for the contents of NO3 (-)-N and NH4 (+)-N in 0-10 cm soil layer, respectively, suggested that the atmospheric nitrogen was one of main sources for soil nitrogen in coastal zone of the YRD.	Nitrogen	268-276	NBL1, DAN family BMP antagonist	Homo sapiens	134-137
24473298-10	2014	FTIR and XPS studies showed that the carboxyl groups, nitrogen atoms and sulfur atoms participated in the adsorption of Pb(II).	Nitrogen	54-62	submaxillary gland androgen regulated protein 3B	Homo sapiens	120-126
24304387-7	2013	Quite interestingly, methylation of the central amide nitrogen strongly altered the high affinity for ABCG2 and the complete inhibition of mitoxantrone efflux and coupled ATPase activity.	Nitrogen	54-62	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	102-107
24338886-2	2013	Using mass spectrometry, we characterized the N-/O-linked glycosylation of recombinant human EPO (rhEPO) produced in glycoengineered Pichia pastoris and compared with the glycosylation of Chinese hamster ovary (CHO) cell-derived rhEPO.	Nitrogen	46-47	erythropoietin	Homo sapiens	93-96
24369062-0	2013	Nitrogen catabolite repressible GAP1 promoter, a new tool for efficient recombinant protein production in S. cerevisiae.	Nitrogen	0-8	amino acid permease GAP1	Saccharomyces cerevisiae S288C	32-36
24369062-3	2013	RESULTS: During this work, a novel promoter system based on the nitrogen catabolite regulation has been developed to produce the general amino acid permease (Gap1) in its natural host, the yeast Saccharomyces cerevisiae.	Nitrogen	64-72	amino acid permease GAP1	Saccharomyces cerevisiae S288C	158-162
24369062-7	2013	CONCLUSIONS: Our work shows that the nitrogen catabolite repressible GAP1 promoter can be used to obtain high levels of recombinant protein while allowing for large biomass production in S. cerevisiae.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	69-73
24460972-2	2013	("Impact on N-glycosylation profile of monoclonal anti-D antibodies as a way to control their immunoregulatory and cytotoxic properties" (2012) Biochemistry (Moscow), 77, 925-933) mentioned the presence of "alien sugars" on monoclonal antibodies (mAbs) produced by YB2/0 cell line.	Nitrogen	12-13	Y box binding protein 3	Rattus norvegicus	265-268
24320827-2	2013	The ribonucleases (RNase, e.g., RNase A) are a large family of hydrolases found in one form or many forms facilitating nitrogen (N) cycling.	Nitrogen	119-127	ribonuclease pancreatic	Bos taurus	32-39
24320827-12	2013	The ability of Ni to convert the activity of plant and animal RNase A from that of a ribonuclease to a urease indicates a possible unrecognized beneficial metabolic function of Ni in organisms, while also identifying a potential detrimental effect of excessive Ni on N related metabolic activity if there is sufficient disruption of Ni homeostasis.	Nitrogen	15-16	ribonuclease pancreatic	Bos taurus	62-69
31986655-6	2013	The coordination nitrogen atoms in two pairs of ortho-positioned nitrogen-containing chelating rings in L1 and L5 are directed toward opposite and the same directions, respectively.	Nitrogen	17-25	L1 cell adhesion molecule	Homo sapiens	104-113
31986655-6	2013	The coordination nitrogen atoms in two pairs of ortho-positioned nitrogen-containing chelating rings in L1 and L5 are directed toward opposite and the same directions, respectively.	Nitrogen	65-73	L1 cell adhesion molecule	Homo sapiens	104-113
23928412-7	2013	N-linked glycoforms were also identified, both in the standard test proteins (transferrin and six protein mixture digest) and the rat liver extract fraction.	Nitrogen	0-1	transferrin	Rattus norvegicus	78-89
24302712-4	2013	In this study, the mRNA level of the PAP isoform CrPAP2 in a species of Chlamydomonas was found to increase in nitrogen-free conditions.	Nitrogen	111-119	uncharacterized protein	Chlamydomonas reinhardtii	49-55
24205994-1	2013	In this work is investigated why the entrance of a nitrogen atom in the ring of cis-2-hydroxypyridine and 2-pyridinone, resulting in cis-4-hydroxypyrimidine and 4(3H)-pyrimidinone, respectively, shifts the tautomeric equilibrium from the hydroxyl form, in the pyridine derivative, to the ketonic form, in the pyrimidine derivative.	Nitrogen	51-59	suppressor of cytokine signaling 6	Homo sapiens	133-138
24218570-1	2013	The assembly of the three neuronal soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) proteins synaptobrevin 2, syntaxin-1A, and SNAP-25 is the key step that leads to exocytotic fusion of synaptic vesicles.	Nitrogen	43-44	vesicle associated membrane protein 2	Homo sapiens	129-144
24312423-1	2013	A series of gold(I) triphenylphosphine (PPh3) complexes (1-9) involving 2-chloro-N6-(substituted-benzyl)adenine derivatives as N-donor ligands was synthesized and thoroughly characterized by relevant methods, including electrospray-ionization (ESI) mass spectrometry and multinuclear NMR spectroscopy.	Nitrogen	81-82	caveolin 1	Homo sapiens	40-44
23988488-9	2013	Using the relative activity factor approach, the hepatic clearance was calculated to be 27 and 73% for 2-O-demethylation by CYP1A2 and CYP3A4, 82, 3, and 15% for 9-O-demethylation by CYP1A2, CYP2C19, and CYP2D6, and finally &lt;1 and 99% for N-demethylation by CYP2D6 and CYP3A4.	Nitrogen	242-243	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	135-141
24089527-6	2013	Suppression of Cav-1 decreased the ubiquitination of COX-2, and mutation of Asn-594 to Ala to disrupt N-glycosylation at the C terminus of COX-2 reduced the interaction of COX-2 with Cav-1 but not Derlin-1.	Nitrogen	102-103	prostaglandin-endoperoxide synthase 2	Homo sapiens	139-144
24085305-9	2013	Consistent with this, mass spectrometric analysis of the mammalian rLILRA3 revealed canonical N-glycosylation at the predicted Asn(140), Asn(281), Asn(302), Asn(341), and Asn(431) sites.	Nitrogen	94-95	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	Rattus norvegicus	67-74
24089527-6	2013	Suppression of Cav-1 decreased the ubiquitination of COX-2, and mutation of Asn-594 to Ala to disrupt N-glycosylation at the C terminus of COX-2 reduced the interaction of COX-2 with Cav-1 but not Derlin-1.	Nitrogen	102-103	prostaglandin-endoperoxide synthase 2	Homo sapiens	139-144
24089527-9	2013	Cav-1 may be a cofactor in the interaction of Derlin-1 and N-glycosylated COX-2 and may facilitate Derlin-1- and p97 complex-mediated COX-2 ubiquitination, retrotranslocation, and degradation.	Nitrogen	59-60	caveolin 1	Homo sapiens	0-5
24089527-9	2013	Cav-1 may be a cofactor in the interaction of Derlin-1 and N-glycosylated COX-2 and may facilitate Derlin-1- and p97 complex-mediated COX-2 ubiquitination, retrotranslocation, and degradation.	Nitrogen	59-60	prostaglandin-endoperoxide synthase 2	Homo sapiens	74-79
24089531-8	2013	In the present study, the presence of NDUFAF7 in the mitochondrial matrix has been confirmed, and it has been demonstrated that it is a protein methylase that symmetrically dimethylates the omega-N(G),N(G") atoms of residue Arg-85 in the NDUFS2 subunit of complex I.	Nitrogen	38-39	NADH:ubiquinone oxidoreductase core subunit S2	Homo sapiens	238-244
24062310-6	2013	Biochemical and genetic analyses using mutant strains of Saccharomyces cerevisiae revealed that the generation of fOSs is tightly correlated with the N-glycosylation activity of OST.	Nitrogen	150-151	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	178-181
24097394-10	2013	CONCLUSIONS: LC/ETD on the Q-ToF system proved effective at characterising a number of different N-linked glyco-forms of the tryptic peptide, EEQYNSTYR, from trastuzumab as well as glyco-forms from the O-linked tryptic peptide, EASIPPDAASAAPLR, from erythropoietin.	Nitrogen	2-3	erythropoietin	Homo sapiens	250-264
24062310-7	2013	Furthermore, we present evidence that the purified OST complex can generate fOSs by hydrolyzing dolichol-linked oligosaccharide, the glycan donor substrate for N-glycosylation.	Nitrogen	160-161	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	51-54
24062310-8	2013	The heterologous expression of a single subunit of OST from the protozoan Leishmania major in S. cerevisiae demonstrated that this enzyme functions both in N-glycosylation and generation of fOSs.	Nitrogen	156-157	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	51-54
23640382-4	2013	CYP2D6 showed a preference for catalyzing N-demethylation of d-DMA, and the intrinsic clearance (Clint) ratio of d-isomer to l-isomer was 1.41.	Nitrogen	42-43	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	0-6
23958596-0	2013	Role of N-glycosylation of human lysosomal phospholipase A2 for the formation of catalytically active enzyme.	Nitrogen	8-9	phospholipase A2 group XV	Homo sapiens	33-59
23896680-1	2013	Industrial nitrogen (N) emissions in the Athabasca oil sands region (AOSR), Alberta, Canada, affect nitrate (NO3) and ammonium (NH4) deposition rates in close vicinity of industrial emitters.	Nitrogen	11-19	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
24455944-3	2013	The contents of CH4 and NO3(-) -N had significant influences on the removal of CH4 and the generation of N2, and there were significant interactions as well (P &lt; 0.05).	Nitrogen	105-107	NBL1, DAN family BMP antagonist	Homo sapiens	24-30
24047900-7	2013	The structures suggest that although a precise fit between the shape of the inhibitor molecules and T. cruzi CYP51 active site topology underlies their high inhibitory potency, a longer coordination bond between the catalytic heme iron and the pyridine nitrogen implies a weaker influence of pyridines on the iron reduction potential, which may be the basis for the observed selectivity of these compounds toward the target enzyme versus other cytochrome P450s, including human drug-metabolizing P450s.	Nitrogen	253-261	cytochrome P450 family 51 subfamily A member 1	Homo sapiens	109-114
23958596-1	2013	To understand the role of N-glycosylation of lysosomal phospholipase A2 (LPLA2), four potential N-glycosylation sites in human LPLA2 (hLPLA2) were individually modified replacing asparagine (Asn) with alanine by site-direct mutagenesis.	Nitrogen	26-27	phospholipase A2 group XV	Homo sapiens	73-78
24428086-8	2013	CONCLUSION: The presence of a high N/C ratio and greater nuclear hyperchromasia could be used to predict high-grade CIN or invasive carcinoma in ASC-H smears.	Nitrogen	2-3	PYD and CARD domain containing	Homo sapiens	145-148
23958596-10	2013	These data indicate that the 99-Asn is the most critical N-glycosylation site for formation of native hLPLA2 in vivo and that the N-glycosylation of LPLA2 is crucial for biosynthesis of catalytically active hLPLA2.	Nitrogen	57-58	phospholipase A2 group XV	Homo sapiens	102-108
23958596-10	2013	These data indicate that the 99-Asn is the most critical N-glycosylation site for formation of native hLPLA2 in vivo and that the N-glycosylation of LPLA2 is crucial for biosynthesis of catalytically active hLPLA2.	Nitrogen	57-58	phospholipase A2 group XV	Homo sapiens	103-108
24072041-6	2013	By investigating the inhibitory mechanism of GS-HCl on renal fibrosis, we found that GS-HCl suppressed TGF-beta signaling by inhibiting N-linked glycosylation of the type II TGF-beta receptor (TbetaRII), leading to an inefficient trafficking of TbetaRII to the membrane surface.	Nitrogen	136-137	transforming growth factor beta 1	Homo sapiens	103-111
24072041-7	2013	Defective N-glycosylation of TbetaRII further suppressed the TGF-beta1-binding to TbetaRII, thereby decreasing TGF-beta signaling.	Nitrogen	10-11	transforming growth factor beta 1	Homo sapiens	61-70
24072041-7	2013	Defective N-glycosylation of TbetaRII further suppressed the TGF-beta1-binding to TbetaRII, thereby decreasing TGF-beta signaling.	Nitrogen	10-11	transforming growth factor beta 1	Homo sapiens	61-69
24072041-11	2013	KEY MESSAGE: Glucosamine-mediated attenuation of TGF-beta signaling ameliorates renal fibrosis in vivo TGF-beta1-induced fibrogenic action is reduced by glucosamine in vitro N-glycosylation of the type II TGF-beta receptor is suppressed by glucosamine Glucosamine-induced defective N-glycosylation of TbetaRII decreases TGF-beta signaling.	Nitrogen	174-175	transforming growth factor beta 1	Homo sapiens	49-57
24072041-11	2013	KEY MESSAGE: Glucosamine-mediated attenuation of TGF-beta signaling ameliorates renal fibrosis in vivo TGF-beta1-induced fibrogenic action is reduced by glucosamine in vitro N-glycosylation of the type II TGF-beta receptor is suppressed by glucosamine Glucosamine-induced defective N-glycosylation of TbetaRII decreases TGF-beta signaling.	Nitrogen	174-175	transforming growth factor beta 1	Homo sapiens	103-112
24144230-6	2013	CONCLUSIONS: We observe that transformations which increased polarity (for example adding an oxygen, or an sp2 nitrogen), decreased lipophilicity (removing carbons), or decreased positive charge consistently reduced hERG inhibition between 3- and 10-fold.	Nitrogen	111-119	ETS transcription factor ERG	Homo sapiens	216-220
24038300-0	2013	Synthesis, characterization, and reactivity of cobalt(III)-oxygen complexes bearing a macrocyclic N-tetramethylated cyclam ligand.	Nitrogen	98-99	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	54-57
24147034-0	2013	The effect of N-acetylation and N-methylation of lysine residue of Tat peptide on its interaction with HIV-1 TAR RNA.	Nitrogen	14-15	RNA binding motif protein 8A	Homo sapiens	109-112
24147034-4	2013	Here we have delineated the thermodynamic and kinetic effects of N-acetylation and N-monomethylation of lysine on interaction between HIV-1 TAR RNA and its cognate binder Tat peptide ( a model system).	Nitrogen	65-66	RNA binding motif protein 8A	Homo sapiens	140-143
24147034-4	2013	Here we have delineated the thermodynamic and kinetic effects of N-acetylation and N-monomethylation of lysine on interaction between HIV-1 TAR RNA and its cognate binder Tat peptide ( a model system).	Nitrogen	83-84	RNA binding motif protein 8A	Homo sapiens	140-143
24228115-7	2013	RESULTS: Blood urea nitrogen and serum creatinine levels were statistically significant high in the group of IAP= 10 and 20cmH2O as compared with the IAP= 0cmH2O.	Nitrogen	20-28	intracisternal A particle, Eya1 linked	Mus musculus	109-113
24014025-4	2013	We discovered that secreted LOXL2 (~100-kDa) is N-glycosylated at Asn-455 and Asn-644, whereas intracellular LOXL2 (~75-kDa) is nonglycosylated and N-terminally processed, and is primarily associated with the nucleus.	Nitrogen	48-49	lysyl oxidase like 2	Homo sapiens	28-33
24124568-4	2013	We quantified the abundance of seven nitrogen-cycling genes, including those for fixation (nifH), mineralization (chiA), nitrification (amoA of ammonia-oxidizing bacteria (AOB) or archaea (AOA)), and denitrification (nirS, nirK and nosZ).	Nitrogen	37-45	chitinase acidic	Homo sapiens	114-118
24155687-8	2013	In contrast, antagonist or transgenic OFQ/N or NOP-R knockout studies, showed augmentation of HPA axis responses to stress, suggesting that OFQ/N may be needed to control the magnitude of the HPA axis response to stress.	Nitrogen	41-43	prepronociceptin	Homo sapiens	140-143
24155687-11	2013	However, it is also suggested that OFQ/N may operate in an anxiolytic manner when initial anxiogenic triggers (eg., the neuropeptide CRH) are initiated.	Nitrogen	39-40	prepronociceptin	Homo sapiens	35-38
24124568-7	2013	In addition, the abundances of the chiA and nosZ genes were sensitive to plant functional group removal, the AOB-amoA gene abundance to phosphorus enrichment when nitrogen was added simultaneously, and the nirS and nirK gene abundances responded to watering.	Nitrogen	163-171	chitinase acidic	Homo sapiens	35-39
23884140-7	2013	Continuous infusion of P78-PEDF for 6 wk resulted in protection from diabetic neuropathy as indicated by reduced albuminuria and blood urea nitrogen, increased nephrin expression, decreased kidney macrophage recruitment and inflammatory cytokines, and reduced histological changes compared with vehicle-treated diabetic mice.	Nitrogen	140-148	serine (or cysteine) peptidase inhibitor, clade F, member 1	Mus musculus	27-31
24270631-0	2013	The evolutionary events necessary for the emergence of symbiotic nitrogen fixation in legumes may involve a loss of nitrate responsiveness of the NIN transcription factor.	Nitrogen	65-73	nin	Lotus japonicus	146-149
23884539-0	2013	Employing tripodal carboxylate ligand to construct Co(II) coordination networks modulated by N-donor ligands: syntheses, structures and magnetic properties.	Nitrogen	93-94	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	51-56
24252310-5	2013	Quantification of confocal microscopy images revealed significantly higher levels of neuronal N-truncated Abeta and HNE and MDA in idiopathic autism and dup(15)/autism than in controls.	Nitrogen	94-95	amyloid beta precursor protein	Homo sapiens	106-111
24270631-1	2013	NODULE INCEPTION (NIN) is a key regulator of the symbiotic nitrogen fixation pathway in legumes including Lotus japonicus.	Nitrogen	59-67	nin	Lotus japonicus	18-21
24270631-6	2013	Because nodule formation is induced under nitrogen-deficient conditions, we speculate that the loss of the nitrate-responsiveness of NIN may be one of the evolutionary events necessary for the emergence of symbiotic nitrogen fixation in legumes.	Nitrogen	42-50	nin	Lotus japonicus	133-136
24270631-6	2013	Because nodule formation is induced under nitrogen-deficient conditions, we speculate that the loss of the nitrate-responsiveness of NIN may be one of the evolutionary events necessary for the emergence of symbiotic nitrogen fixation in legumes.	Nitrogen	216-224	nin	Lotus japonicus	133-136
23912081-3	2013	The results demonstrate that URG7 is N-glycosylated and located to the endoplasmic reticulum membrane with an Nlumen-Ccytosol orientation.	Nitrogen	37-38	ATP binding cassette subfamily C member 6	Homo sapiens	29-33
23932790-0	2013	A hit to lead discovery of novel N-methylated imidazolo-, pyrrolo-, and pyrazolo-pyrimidines as potent and selective mTOR inhibitors.	Nitrogen	33-34	mechanistic target of rapamycin kinase	Homo sapiens	117-121
23549421-4	2013	We demonstrate that the mutation inactivates ceramide synthase 3 (CerS3), which is synthesized in skin and testis, in an assay of N-acylation with C26-CoA, both in patient keratinocytes and using recombinant mutant proteins.	Nitrogen	130-131	ceramide synthase 3	Homo sapiens	45-64
24039956-3	2013	Additionally, the C. parasitica Prodh and P5Cdh genes were able to complement the Saccharomyces cerevisiae put1 and put2 null mutants, respectively, to allow these proline auxotrophic yeast mutants to grow on media with proline as the sole source of nitrogen.	Nitrogen	250-258	proline dehydrogenase	Saccharomyces cerevisiae S288C	107-111
23942187-5	2013	Significantly, genes coding for protein O-mannosyltransferase 2 (Pmt2p), which is responsible for the addition of the first mannosyl residue of O-linked carbohydrates, and for Eos1p, an enzyme involved in N-linked glycosylation of proteins, showed resistance to PAF26 and defects in CW integrity.	Nitrogen	205-206	dolichyl-phosphate-mannose-protein mannosyltransferase PMT2	Saccharomyces cerevisiae S288C	65-70
24039863-4	2013	Here, we analyzed N-glycosylation profiles of alpha1-antitrypsin (AAT) and immunoglobulin A (IgA) enriched fractions by 96-well microtitration plate based high-throughput immuno-affinity capturing and N-glycan analysis using multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (CGE-LIF).	Nitrogen	18-19	serpin family A member 1	Homo sapiens	46-64
24039863-4	2013	Here, we analyzed N-glycosylation profiles of alpha1-antitrypsin (AAT) and immunoglobulin A (IgA) enriched fractions by 96-well microtitration plate based high-throughput immuno-affinity capturing and N-glycan analysis using multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (CGE-LIF).	Nitrogen	18-19	serpin family A member 1	Homo sapiens	66-69
24039863-4	2013	Here, we analyzed N-glycosylation profiles of alpha1-antitrypsin (AAT) and immunoglobulin A (IgA) enriched fractions by 96-well microtitration plate based high-throughput immuno-affinity capturing and N-glycan analysis using multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (CGE-LIF).	Nitrogen	18-19	CD79a molecule	Homo sapiens	75-91
24039863-4	2013	Here, we analyzed N-glycosylation profiles of alpha1-antitrypsin (AAT) and immunoglobulin A (IgA) enriched fractions by 96-well microtitration plate based high-throughput immuno-affinity capturing and N-glycan analysis using multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (CGE-LIF).	Nitrogen	18-19	CD79a molecule	Homo sapiens	93-96
24252153-12	2013	CONCLUSIONS: Abeta4-x precedes AbetapE3-x in the well accepted 5XFAD AD mouse model underlining the significance of N-truncated species in AD pathology.	Nitrogen	2-3	CD93 antigen	Mus musculus	13-19
23901877-6	2013	We focused on the trisialylated N-glycan fraction from haptoglobin and human plasma, enriched using weak anion exchange chromatography, as this trisialylated fraction has been linked with cancer associated changes in the serum N-glycome.	Nitrogen	32-33	haptoglobin	Homo sapiens	55-66
23864002-11	2013	Finally, the photosynthetic pathway (C3 vs. CAM) was positively correlated with leaf N concentration with a slightly higher N concentration for C3-Tillandsioideae compared with CAM-Bromelioideae.	Nitrogen	85-86	calmodulin 3	Homo sapiens	37-47
23864002-11	2013	Finally, the photosynthetic pathway (C3 vs. CAM) was positively correlated with leaf N concentration with a slightly higher N concentration for C3-Tillandsioideae compared with CAM-Bromelioideae.	Nitrogen	85-86	calmodulin 3	Homo sapiens	44-47
24289004-8	2013	In addition, reduced nitrogen (NH4+ and NH3) contributed to 71% of the total deposition, while oxidation nitrogen (NO3- and NO2) was only 29%.	Nitrogen	105-113	NBL1, DAN family BMP antagonist	Homo sapiens	115-118
24078243-13	2013	Metabolites formed by N-dealkylation are M5, M6a, and M6b.	Nitrogen	22-23	glycoprotein M6B	Homo sapiens	54-57
23549421-4	2013	We demonstrate that the mutation inactivates ceramide synthase 3 (CerS3), which is synthesized in skin and testis, in an assay of N-acylation with C26-CoA, both in patient keratinocytes and using recombinant mutant proteins.	Nitrogen	130-131	ceramide synthase 3	Homo sapiens	66-71
24224284-7	2013	With the CO boost, N2 washout increased 6% breathing O2 at -15 cmH2O CNPB and INPB, while during normoxic breathing there were 6% and 12% increases due to CNBP, -10 and -15 respectively and 6% with -15cmH2O INPB; breathing 100% O2 yielding 5% to 15% less N2 washout than normoxic breathing.	Nitrogen	19-21	troponin T2, cardiac type	Homo sapiens	63-67
23824793-9	2013	CD4 independence and neutralization sensitivity were both conferred by Env amino acid changes E84K and D470N that arose independently in multiple animals, with the latter introducing a potential N-linked glycosylation site within a predicted CD4-binding pocket of gp120.	Nitrogen	107-108	CD4 molecule	Homo sapiens	0-3
23708432-6	2013	Analysis of de-N-glycosylated EPO showed the distributions of O-glycans of NeuAc1-2Hex1HexNAc1 and site occupancy.	Nitrogen	15-16	erythropoietin	Homo sapiens	30-33
23977108-0	2013	RuvBL2 is involved in histone deacetylase inhibitor PCI-24781-induced cell death in SK-N-DZ neuroblastoma cells.	Nitrogen	86-88	RuvB like AAA ATPase 2	Homo sapiens	0-6
23945047-8	2013	In addition, 15 N-labeled ABF-2 and a well-dispersed heteronuclear single quantum coherence (HSQC) spectrum were also obtained successfully.	Nitrogen	16-17	Antibacterial factor-related peptide 2	Caenorhabditis elegans	26-31
24404057-4	2013	In this study, we present a systematic experimental investigation on the role of N-glycosylation for VWF mediated platelet adhesion under flow.	Nitrogen	81-82	von Willebrand factor	Homo sapiens	101-104
23829323-0	2013	Exploring site-specific N-glycosylation microheterogeneity of haptoglobin using glycopeptide CID tandem mass spectra and glycan database search.	Nitrogen	24-25	haptoglobin	Homo sapiens	62-73
23829323-8	2013	Our software, GlycoPeptideSearch (GPS), assigned glycopeptide identifications to 246 of the spectra at a false discovery rate of 5.58%, identifying 42 distinct haptoglobin peptide-glycan pairs at each of the four haptoglobin N-linked glycosylation sites.	Nitrogen	225-226	haptoglobin	Homo sapiens	160-171
23815085-2	2013	Here we have shown the involvement of N-glycosylation in the MMP inhibitory ability of TIMP-1.	Nitrogen	38-39	TIMP metallopeptidase inhibitor 1	Homo sapiens	87-93
23829323-9	2013	We further demonstrate the effectiveness of this approach by analyzing plasma-derived haptoglobin, identifying 136 N-linked glycopeptide spectra at a false discovery rate of 0.4%, representing 15 distinct glycopeptides on at least three of the four N-linked glycosylation sites.	Nitrogen	115-116	haptoglobin	Homo sapiens	86-97
23737077-3	2013	Substituents on the N atom of the imidazole ring appear to have a significant effect on the inhibition of LPO-catalyzed oxidation and iodination reactions.	Nitrogen	20-21	lactoperoxidase	Homo sapiens	106-109
23188459-5	2013	Biochemical characterization of AtDIR6 produced with P. pastoris showed an overall agreement in protein structure, N-glycosylation sites, and dirigent activity compared to AtDIR6 produced by plant cell cultures of Solanum peruvianum.	Nitrogen	115-116	Disease resistance-responsive (dirigent-like protein) family protein	Arabidopsis thaliana	32-38
23897470-12	2013	These findings suggest that yNit2 may have broad biological roles in yeast, especially in regard to nitrogen homeostasis, and provide a framework for the elucidation of the substrate specificity and biological role of mammalian Nit1.	Nitrogen	100-108	putative hydrolase	Saccharomyces cerevisiae S288C	28-33
23907880-2	2013	Ag1 is five-coordinated by three O atoms from one L1 anion, one L2 anion and one water molecule, one N atom from one L2 anion and one AgI cation in a distorted trigonal-bipyramidal coordination geometry.	Nitrogen	101-102	NBPF member 10	Homo sapiens	0-3
23837729-4	2013	To gain access to the S3 and S3 subpocket of the BACE1 active site, various linkers are described including nitrogen- and oxygen-based, aryl, and amide-based linkers.	Nitrogen	108-116	beta-secretase 1	Homo sapiens	49-54
23092637-10	2013	CONCLUSIONS: The PCK1 rs2179706 polymorphism interacts with plasma concentration of n - 3 PUFA levels modulating insulin resistance in MetS subjects.	Nitrogen	46-47	insulin	Homo sapiens	113-120
23580236-0	2013	Analysis of haptoglobin N-glycome alterations in inflammatory and malignant lung diseases by capillary electrophoresis.	Nitrogen	24-25	haptoglobin	Homo sapiens	12-23
23580236-1	2013	A CE-based method was introduced to compare the N-glycosylation profile of haptoglobin in normal and pathologic conditions.	Nitrogen	48-49	haptoglobin	Homo sapiens	75-86
23408601-6	2013	After adjustment for aBMD, men in the highest sclerostin quartile had higher Tb.vBMD (mainly in the central compartment) and Tb.N at both skeletal sites (p &lt; 0.05 to 0.001).	Nitrogen	128-129	sclerostin	Homo sapiens	46-56
23722157-2	2013	Upon nitrogen starvation, GFP-Atg8-containing pre-autophagosomal puncta give rise to cup-shaped phagophores and circular (0.9-mum diameter) autophagosomes that disappear in the vicinity of the vacuoles after their shape becomes irregular and their GFP-Atg8 fluorescence decays.	Nitrogen	5-13	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	30-34
23706267-6	2013	Results of molecular docking studies revealed that COX-2 pharmacophore SO2NH2 in compound 30 is positioned in the secondary pocket of COX-2 active site; with the nitrogen atom of the SO2NH2 group being hydrogen bonded to Q192 (N OC=2.85A), and one of the oxygen atoms of SO2NH2 group forming a hydrogen bond to H90 (SO N=2.38A).	Nitrogen	162-170	prostaglandin-endoperoxide synthase 2	Homo sapiens	51-56
23706267-6	2013	Results of molecular docking studies revealed that COX-2 pharmacophore SO2NH2 in compound 30 is positioned in the secondary pocket of COX-2 active site; with the nitrogen atom of the SO2NH2 group being hydrogen bonded to Q192 (N OC=2.85A), and one of the oxygen atoms of SO2NH2 group forming a hydrogen bond to H90 (SO N=2.38A).	Nitrogen	162-170	prostaglandin-endoperoxide synthase 2	Homo sapiens	134-139
23688541-6	2013	The expression levels of tyrosine hydroxylase (TH), dopamine transporter (DAT) and vesicular monoamine transporter 2(VMAT-2) were significantly decreased and the activity/levels of reactive oxygen species (ROS), nitric oxide synthase (NOS) and nitrogen (NO) were notably increased after METH treatment.	Nitrogen	244-252	tyrosine hydroxylase	Homo sapiens	25-45
23776238-4	2013	We then investigated the effect of N-glycosylation on the function of BCMA and found that the dexamethasone-induced apoptosis in malignant plasma cells can be rescued by treatment with BCMA ligands, such as a proliferation-inducing ligand (APRIL) and B-cell-activating factor (BAFF), whereas removal of terminal sialic acid on plasma cells further potentiated the ligand-mediated protection.	Nitrogen	35-36	TNF superfamily member 13	Homo sapiens	207-238
23541506-4	2013	This paper describes a comparative study of the thermodynamics of unmodified and modified Tat peptide interaction with TAR RNA, where the peptide is methylated at epsilon (e) and eta (eta) nitrogen atoms of guanidinium group of arginine side chain at position 52 or 53.	Nitrogen	189-197	RNA binding motif protein 8A	Homo sapiens	119-122
23698308-0	2013	Unique N-linked glycosylation of CasBrE Env influences its stability, processing, and viral infectivity but not its neurotoxicity.	Nitrogen	7-8	melanoma antigen	Mus musculus	40-43
23698308-11	2013	Thus, while unique N-glycosylation affected structural features of Env involved in protein stability, proteolytic processing, and virus assembly and entry, these changes had minimal impact on CasBrE Env neurotoxicity.	Nitrogen	19-20	melanoma antigen	Mus musculus	67-70
24137346-4	2013	In the lung tissues from the RT+NS group, the malondialdehyde (MDA) levels were significantly elevated and superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) activities were significantly reduced; the total cell counts and inflammatory cell proportions in the bronchoalveolar lavage fluid (BALF), plasma tumor necrosis factor (TNF)-alpha and transforming growth factor (TGF)-beta1 concentrations and the hydroxyproline (HP) content were significantly increased.	Nitrogen	32-34	tumor necrosis factor	Mus musculus	316-349
23936187-5	2013	Among PrP"s essential features, the N-terminal leader peptide was sufficient to drive targeting of our constructs to cell contact sites, whereas lack of GPI-anchoring and N-glycosylation rendered them inactive by blocking their cell surface expression.	Nitrogen	36-37	prion protein	Homo sapiens	6-9
23983629-2	2013	Loss of NO3-N in soils due to leaching is not only one of the most important problems in agriculture farming, but is also the main factor causing nitrogen pollution in aquatic environments.	Nitrogen	146-154	NBL1, DAN family BMP antagonist	Homo sapiens	8-11
23738747-1	2013	Recent studies suggest that cyanate (OCN(-)) is a potentially important source of reduced nitrogen (N) available to support the growth of aquatic microbes and, thus, may play a role in aquatic N cycling.	Nitrogen	90-98	bone gamma-carboxyglutamate protein	Homo sapiens	37-40
23552866-8	2013	The therapeutic effect of the anti-TGF-beta antibody was further confirmed by its prevention of graft dysfunction, indicated by lower levels of serum creatinine and blood urea nitrogen or higher creatinine clearance in anti-TGF-beta antibody-treated recipients compared with those in control recipients (P &lt; 0.05).	Nitrogen	176-184	transforming growth factor, beta 1	Rattus norvegicus	35-43
23703614-0	2013	N-glycosylation induces the CTHRC1 protein and drives oral cancer cell migration.	Nitrogen	0-1	collagen triple helix repeat containing 1	Homo sapiens	28-34
23703614-6	2013	Partial inhibition of DPAGT1 expression in OSCC CAL27 cells reduced CTHRC1 abundance by increasing protein turnover, indicating that N-glycosylation stabilizes CTHRC1.	Nitrogen	133-134	collagen triple helix repeat containing 1	Homo sapiens	160-166
23703614-9	2013	We propose that in OSCC, dysregulation of canonical Wnt signaling and DPAGT1-dependent N-glycosylation induces CTHRC1, thereby driving OSCC cell migration and tumor spread.	Nitrogen	87-88	collagen triple helix repeat containing 1	Homo sapiens	111-117
23774830-6	2013	The enzyme kinetic studies showed that the initial metabolic step in humans, the N-deethylation, was catalyzed by CYP2B6 and CYP3A4.	Nitrogen	81-82	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	125-131
23722157-2	2013	Upon nitrogen starvation, GFP-Atg8-containing pre-autophagosomal puncta give rise to cup-shaped phagophores and circular (0.9-mum diameter) autophagosomes that disappear in the vicinity of the vacuoles after their shape becomes irregular and their GFP-Atg8 fluorescence decays.	Nitrogen	5-13	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	252-256
24027997-9	2013	When the pE value continued to increase from 6.85 to 8.15, the nitrogen form changed from NO2- to NO3-, and the suppression effect on ANT photodegradation decreased.	Nitrogen	63-71	NBL1, DAN family BMP antagonist	Homo sapiens	98-101
23552177-1	2013	The human cytochrome P450 2D6 (CYP2D6) is one of the major human drug metabolizing enzymes and acts preferably on substrates containing a basic nitrogen atom.	Nitrogen	144-152	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	10-29
23552177-1	2013	The human cytochrome P450 2D6 (CYP2D6) is one of the major human drug metabolizing enzymes and acts preferably on substrates containing a basic nitrogen atom.	Nitrogen	144-152	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	31-37
27121790-1	2013	Glycerol tri-(4-phenylbutyrate) (glycerol phenylbutyrate, GPB, HPN-100) mediates waste nitrogen excretion through conjugation with glutamine to form phenylacetylglutamine which is excreted in urine.	Nitrogen	87-95	glycophorin B (MNS blood group)	Homo sapiens	58-61
24313205-9	2013	The concentration of OVA-sIgE was higher in LD group than that of NS group (t = -2.53, P &lt; 0.05), but similar with that of NS + AL group (t = -2.04, P &gt; 0.05).	Nitrogen	66-68	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	21-24
24027997-5	2013	Presence of different forms of inorganic nitrogen (NH4+, NO2- and NO3-) showed rather different effects.	Nitrogen	41-49	NBL1, DAN family BMP antagonist	Homo sapiens	66-69
23594281-10	2013	Serum blood urea nitrogen (BUN) levels differed significantly between MPO-ANCA-positive and -negative patients.	Nitrogen	17-25	myeloperoxidase	Homo sapiens	70-73
23957201-6	2013	The activation of ERK and p38 was down-regulated when rats were exposed to normoxic hyperbaric nitrogen for 10 hours.	Nitrogen	95-103	Eph receptor B1	Rattus norvegicus	18-21
23668542-3	2013	Utilizing PCR-based site-directed mutagenesis, new A1AT variants were created with single, double, or triple additional N-glycosylation sites to the three naturally occurring N-glycosylation sites.	Nitrogen	120-121	serpin family A member 1	Homo sapiens	51-55
23668542-3	2013	Utilizing PCR-based site-directed mutagenesis, new A1AT variants were created with single, double, or triple additional N-glycosylation sites to the three naturally occurring N-glycosylation sites.	Nitrogen	175-176	serpin family A member 1	Homo sapiens	51-55
23668542-8	2013	The relevance of N-glycosylation in A1AT for the circulatory serum half-life was demonstrated in CD1 mice.	Nitrogen	17-18	serpin family A member 1	Homo sapiens	36-40
23668542-9	2013	The A1AT neoglycoprotein with an additional N-glycosylation site at position N123 exhibited a 62% increase in serum half-life.	Nitrogen	44-45	serpin family A member 1	Homo sapiens	4-8
22975359-2	2013	The aim of this study was to further investigate the effects of NS-398 on the changes in expression and/or activity of COX-2, cytochrome P450 4A1 (CYP4A1), inducible NO synthase (iNOS), and peroxynitrite formation in serum, renal, cardiac, and/or vascular tissues of lipopolysaccharide (LPS)-treated rats.	Nitrogen	64-66	cytochrome P450, family 4, subfamily a, polypeptide 1	Rattus norvegicus	126-145
22975359-2	2013	The aim of this study was to further investigate the effects of NS-398 on the changes in expression and/or activity of COX-2, cytochrome P450 4A1 (CYP4A1), inducible NO synthase (iNOS), and peroxynitrite formation in serum, renal, cardiac, and/or vascular tissues of lipopolysaccharide (LPS)-treated rats.	Nitrogen	64-66	cytochrome P450, family 4, subfamily a, polypeptide 1	Rattus norvegicus	147-153
22975359-2	2013	The aim of this study was to further investigate the effects of NS-398 on the changes in expression and/or activity of COX-2, cytochrome P450 4A1 (CYP4A1), inducible NO synthase (iNOS), and peroxynitrite formation in serum, renal, cardiac, and/or vascular tissues of lipopolysaccharide (LPS)-treated rats.	Nitrogen	64-66	nitric oxide synthase 2	Rattus norvegicus	156-177
22975359-2	2013	The aim of this study was to further investigate the effects of NS-398 on the changes in expression and/or activity of COX-2, cytochrome P450 4A1 (CYP4A1), inducible NO synthase (iNOS), and peroxynitrite formation in serum, renal, cardiac, and/or vascular tissues of lipopolysaccharide (LPS)-treated rats.	Nitrogen	64-66	nitric oxide synthase 2	Rattus norvegicus	179-183
24313205-12	2013	The ratio of IFN-gamma/IL-4 was significantly lower in SD group than that of NS and NS + AL group (t value was 2.14, 3.44, all P &lt; 0.05), while the same ratio was higher in LD group than that of NS and NS + AL group (t value was -2.14, -1.61, all P &lt; 0.05).	Nitrogen	77-79	interferon gamma	Mus musculus	13-22
24313205-12	2013	The ratio of IFN-gamma/IL-4 was significantly lower in SD group than that of NS and NS + AL group (t value was 2.14, 3.44, all P &lt; 0.05), while the same ratio was higher in LD group than that of NS and NS + AL group (t value was -2.14, -1.61, all P &lt; 0.05).	Nitrogen	84-86	interferon gamma	Mus musculus	13-22
24313205-12	2013	The ratio of IFN-gamma/IL-4 was significantly lower in SD group than that of NS and NS + AL group (t value was 2.14, 3.44, all P &lt; 0.05), while the same ratio was higher in LD group than that of NS and NS + AL group (t value was -2.14, -1.61, all P &lt; 0.05).	Nitrogen	84-86	interferon gamma	Mus musculus	13-22
23665562-0	2013	Synip arrests soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)-dependent membrane fusion as a selective target membrane SNARE-binding inhibitor.	Nitrogen	22-23	syntaxin binding protein 4	Homo sapiens	0-5
24313205-10	2013	Both the concentration of OVA-sIgG1 and sIgG2a was higher in SD and LD group than that of NS and NS + AL group (all P &lt; 0.05).	Nitrogen	90-92	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	26-29
23606741-0	2013	OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation.	Nitrogen	84-85	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	35-60
23776650-6	2013	Since DCIR has an N-glycosylation site inside its carbohydrate recognition domain (CRD), we investigated the effect of this glycan in ligand recognition.	Nitrogen	18-19	C-type lectin domain family 4 member A	Homo sapiens	6-10
23606741-1	2013	The eukaryotic oligosaccharyltransferase (OST) is a membrane-embedded protein complex that catalyses the N-glycosylation of nascent polypeptides in the lumen of the endoplasmic reticulum (ER), a highly conserved biosynthetic process that enriches protein structure and function.	Nitrogen	105-106	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	15-40
23606741-1	2013	The eukaryotic oligosaccharyltransferase (OST) is a membrane-embedded protein complex that catalyses the N-glycosylation of nascent polypeptides in the lumen of the endoplasmic reticulum (ER), a highly conserved biosynthetic process that enriches protein structure and function.	Nitrogen	105-106	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	42-45
23606741-11	2013	We conclude that OST4 most likely promotes co-translational N-glycosylation by stabilising STT3A-containing OST isoforms.	Nitrogen	60-61	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	17-20
23462539-6	2013	Like pd-A1PI, Hu-recA1PI was modified by N-linked glycosylation on N46, N83, and N246.	Nitrogen	41-42	serpin family A member 1	Homo sapiens	8-12
23550066-1	2013	Ketamine is primarily metabolized to norketamine by hepatic CYP2B6 and CYP3A4-mediated N-demethylation.	Nitrogen	87-88	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	71-77
24191599-5	2013	In river without highly circulating irrigation system or water gate effect, the downstream nitrate nitrogen (NO3-N) concentration increase occurred in area dominated by open field cultivation, whereas the NO3-N concentration was constant or decreased in area dominated by greenhouse land use.	Nitrogen	99-107	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
23517290-2	2013	Rsp5 triggers the ubiquitination-dependent endocytosis of the general amino acid permease Gap1 in response to a good nitrogen source.	Nitrogen	117-125	amino acid permease GAP1	Saccharomyces cerevisiae S288C	90-94
23750472-6	2013	All forms of human c-Mpl protein were found to be modified with extensive N-linked glycosylation but different degrees of sialylation and O-linked glycosylation.	Nitrogen	74-75	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	19-24
23624514-6	2013	Meigo positively regulated the level of Ephrin N-glycosylation, which was required for its optimal function in vivo.	Nitrogen	47-48	ephrin	Drosophila melanogaster	40-46
23647004-0	2013	Integration of Monte Carlo simulations with PFGE experimental data yields constant RBE of 2.3 for DNA double-strand break induction by nitrogen ions between 125 and 225 keV/mum LET.	Nitrogen	135-143	sulfatase modifying factor 2	Homo sapiens	44-48
23647004-0	2013	Integration of Monte Carlo simulations with PFGE experimental data yields constant RBE of 2.3 for DNA double-strand break induction by nitrogen ions between 125 and 225 keV/mum LET.	Nitrogen	135-143	latexin	Homo sapiens	173-176
23647004-6	2013	When the measured distributions of fragment masses are converted into fragment distributions using the average fragment lengths calculated by PARTRAC, significantly higher yields of DSB related to short fragments were obtained and resulted in a constant relative biological effectiveness (RBE) for DSB induction yield of 2.3 for nitrogen ions at 125-225 keV/mum LET.	Nitrogen	329-337	latexin	Homo sapiens	358-361
23474170-10	2013	The targeting of iNOS protein to the peroxisome may shift the balance of metabolic processes that rely on heme proteins susceptible to modification by radical oxygen and nitrogen radicals.	Nitrogen	170-178	nitric oxide synthase 2, inducible	Mus musculus	17-21
23470981-4	2013	The glycosylated and non-N-glycosylated versions of this recombinant protein each bind to a porcine CD80 expressing B-cell lymphoma line (LCL13271) with equal affinity (K(D)=13 nM).	Nitrogen	25-26	CD80 antigen	Mus musculus	100-104
23666577-4	2013	O-demethylation is catalyzed by the highly polymorphic CYP2D6 and N-demethylation by several enzymes, CYP2C19, CYP2C9, and CYP3A4.	Nitrogen	66-67	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	123-129
23724116-0	2013	N-linked glycosylation supports cross-talk between receptor tyrosine kinases and androgen receptor.	Nitrogen	0-1	androgen receptor	Homo sapiens	81-98
23328887-4	2013	This perspective will highlight the new synthetic routes for NHC bearing a phosphorus moiety such as NHC-phosphenium salt, N-phosphorylated-imidazolium salt, 4-phosphino or 4,5-diphosphino-imidazolium salt and tethered phosphino-imidazolium salt.	Nitrogen	61-62	high mobility group nucleosomal binding domain 4	Homo sapiens	101-104
23586743-2	2013	The reaction of cyc-N3 with hydrogen is shown to proceed through a barrierless path that dissociates to N2 + NH((1)Delta) without reaching the HN3 global minimum.	Nitrogen	104-108	cytochrome c, somatic	Homo sapiens	16-19
23713126-4	2013	Leaching and riverine transport of NO3 contribute 40-70 Tg N yr(-1) to coastal waters and the open ocean, which together with the 30 Tg input to oceans from atmospheric deposition combine with marine biological nitrogen fixation (140 Tg N yr(-1)) to double the ocean processing of Nr.	Nitrogen	211-219	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
23508268-4	2013	The tbta ligand binds to the Co(II) centers through the three triazole nitrogen donor atoms in a facial form, with the Co-N(amine) distance of 2.494(2) A acting as a capping bond to the octahedron.	Nitrogen	71-79	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	29-35
23486012-11	2013	Phenotypically normal mice heterozygous for the Aqp11 mutation repeatedly treated with glucose showed increased blood urea nitrogen levels that were prevented by the antioxidant sulforaphane or by phlorizin.	Nitrogen	123-131	aquaporin 11	Mus musculus	48-53
23380952-6	2013	In this study, 3-AQ/CHCA LM was applied to tryptic digests of HER2 to reveal its N-glycosylation state and to evaluate the utility of this LM in characterizing glycopeptides.	Nitrogen	81-82	erb-b2 receptor tyrosine kinase 2	Homo sapiens	62-66
23556518-0	2013	N-linked glycosylation is required for transferrin-induced stabilization of transferrin receptor 2, but not for transferrin binding or trafficking to the cell surface.	Nitrogen	0-1	transferrin	Homo sapiens	39-50
23556518-0	2013	N-linked glycosylation is required for transferrin-induced stabilization of transferrin receptor 2, but not for transferrin binding or trafficking to the cell surface.	Nitrogen	0-1	transferrin	Homo sapiens	76-87
23717280-9	2013	Published studies from my laboratory demonstrate that in human cerebrospinal fluid immunoreactive Abeta is only present as a complex with two chaperones, ERp57 and calreticulin and is N-glycosylated.	Nitrogen	184-185	amyloid beta precursor protein	Homo sapiens	98-103
23515315-13	2013	However, in vitro, we find Hha improves H-NS binding to target DNA fragments.	Nitrogen	42-44	anosmin 1	Homo sapiens	27-30
23675534-7	2013	We found that the number of Treg cells and the levels of the Treg cell-related transcription factor (Foxp3) and cytokines (IL-10) in the zymosan-treated group significantly decreased on day 1 and day 2 and significantly increased on day 5 compared with the NS-treated group.	Nitrogen	257-259	interleukin 10	Mus musculus	123-128
23404373-6	2013	The abundance of one metabolite, the N-dealkylated nitroso/oxime lapatinib metabolite (M9), correlated directly with the prevalence or the disruption of the MI complex with CYP3A4.	Nitrogen	37-38	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	173-179
23561569-9	2013	The N content of sulfanilamide was mainly mineralized as NH4+ ion and in much lesser extent as NO3- ion, whereas most of its initial S was converted into SO42- ion.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	95-98
23404373-9	2013	Our findings support the mechanism of lapatinib CYP3A4 inactivation as MI complex formation with the nitroso metabolite formed through the secondary hydroxylamine and nitrone pathway, rather than by N-dealkylation to the primary amine followed by N-hydroxylation and dehydrogenation as is usually assumed.	Nitrogen	199-200	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	48-54
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	77-85	Dur3p	Saccharomyces cerevisiae S288C	40-44
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	77-85	amino acid permease GAP1	Saccharomyces cerevisiae S288C	49-53
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	148-156	Dur3p	Saccharomyces cerevisiae S288C	40-44
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	148-156	amino acid permease GAP1	Saccharomyces cerevisiae S288C	49-53
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	148-156	amino acid permease GAP1	Saccharomyces cerevisiae S288C	106-110
23490150-4	2013	An X-ray co-crystal structure of 19b with EGFR demonstrated that the N-1 and N-3 nitrogens of the pyrimido[4,5-b]azepine scaffold make hydrogen-bonding interactions with the main chain NH of Met793 and the side chain of Thr854 via a water-mediated hydrogen bond network, respectively.	Nitrogen	81-90	epidermal growth factor receptor	Homo sapiens	42-46
23713139-10	2013	A  gap1 population has a selective advantage on allantoin or ammonium as a nitrogen source and high stress tolerance.	Nitrogen	75-83	amino acid permease GAP1	Saccharomyces cerevisiae S288C	3-7
23418736-6	2013	A time-dependent Na+-dependent glutamate/aspartate transporter/EAAT1-induced System N-mediated glutamine release could be demonstrated.	Nitrogen	17-18	solute carrier family 1 member 3	Homo sapiens	63-68
23389049-1	2013	Haptoglobin is a liver-secreted glycoprotein with four N-glycosylation sites.	Nitrogen	55-56	haptoglobin	Homo sapiens	0-11
23549797-8	2013	Using an arbitrary cut off value, S100B-positive CSF was detected in 2.5% of the CNS-N group and in 50% of the CNS+N group (p&lt;0.05).	Nitrogen	82-83	S100 calcium binding protein B	Homo sapiens	34-39
23549797-8	2013	Using an arbitrary cut off value, S100B-positive CSF was detected in 2.5% of the CNS-N group and in 50% of the CNS+N group (p&lt;0.05).	Nitrogen	85-86	S100 calcium binding protein B	Homo sapiens	34-39
23658613-7	2013	Deletion of SCH9 increased yeast viability in the presence of excess nitrogen, indicating that a signalling pathway acting through Sch9p is involved in this nitrogen-triggered cell death.	Nitrogen	69-77	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	12-16
23658613-7	2013	Deletion of SCH9 increased yeast viability in the presence of excess nitrogen, indicating that a signalling pathway acting through Sch9p is involved in this nitrogen-triggered cell death.	Nitrogen	157-165	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	12-16
23658613-7	2013	Deletion of SCH9 increased yeast viability in the presence of excess nitrogen, indicating that a signalling pathway acting through Sch9p is involved in this nitrogen-triggered cell death.	Nitrogen	157-165	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	131-136
23342972-2	2013	These functions concern three major areas: nitrogen transportation via the glutamine synthetase and glutamine-oxoglutarate aminotransferase cycle, cellular redox regulation, and tricarboxylic acid cycle-dependent energy reprogramming.	Nitrogen	43-51	glutamate-ammonia ligase	Homo sapiens	75-95
23673980-2	2013	Eukaryotes have conserved N-myristoylation enzymes, involving one or two N-myristoyltransferases (NMT1 and NMT2), among which NMT1 is the major enzyme.	Nitrogen	26-27	myristoyl-CoA:protein N-myristoyltransferase	Arabidopsis thaliana	98-102
23673980-2	2013	Eukaryotes have conserved N-myristoylation enzymes, involving one or two N-myristoyltransferases (NMT1 and NMT2), among which NMT1 is the major enzyme.	Nitrogen	26-27	myristoyl-CoA:protein N-myristoyltransferase	Arabidopsis thaliana	126-130
23673980-8	2013	Our results provide important functional insight into N-myristoylation in plants by ascribing postembryonic functions of Arabidopsis NMT1 that involve regulation of the functional and morphological integrity of the plant endomembranes.	Nitrogen	54-55	myristoyl-CoA:protein N-myristoyltransferase	Arabidopsis thaliana	133-137
23435550-0	2013	First structurally characterized self-assembly of bipodal N-thiophosphorylated bis-thiourea with Co(II): magnetic properties and thermal decomposition.	Nitrogen	58-59	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	97-103
23422691-2	2013	VEGF is a homodimeric glycoprotein that contains one N-glycosylation site.	Nitrogen	53-54	vascular endothelial growth factor A	Homo sapiens	0-4
23422691-7	2013	N-glycosylation in the pro region was required for the prepro sequence to promote VEGF secretion.	Nitrogen	0-1	vascular endothelial growth factor A	Homo sapiens	82-86
23397567-1	2013	Ure2p, normally a regulator of nitrogen catabolism in Saccharomyces cerevisiae, can be a prion (infectious protein) by forming a folded in-register parallel amyloid called [URE3].	Nitrogen	31-39	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
23361230-10	2013	They were also involved in the N-demethylation of the analogue methamphetamine and CYP2C19, CYP2D6, and CYP3A4 in its ring hydroxylation.	Nitrogen	31-32	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	92-98
23361230-10	2013	They were also involved in the N-demethylation of the analogue methamphetamine and CYP2C19, CYP2D6, and CYP3A4 in its ring hydroxylation.	Nitrogen	31-32	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	104-110
23392238-2	2013	This study aimed to clarify the regulation of N elimination via urea during different phases of the tumor necrosis factor-alpha (TNF-alpha)-induced acute-phase response in rats.	Nitrogen	46-47	tumor necrosis factor	Rattus norvegicus	100-127
23392238-2	2013	This study aimed to clarify the regulation of N elimination via urea during different phases of the tumor necrosis factor-alpha (TNF-alpha)-induced acute-phase response in rats.	Nitrogen	46-47	tumor necrosis factor	Rattus norvegicus	129-138
23506325-3	2013	RESULTS: We demonstrate here that PRG3 induces filopodia formation in HEK293 cells depending on its N-glycosylation status.	Nitrogen	100-101	phospholipid phosphatase related 1	Homo sapiens	34-38
23438973-5	2013	The second part provides insights into vasopressin physiology and pathophysiology that may be relevant to the understanding of these adverse effects and that are linked to the excretion of concentrated nitrogen wastes and associated hyperfiltration.	Nitrogen	202-210	arginine vasopressin	Homo sapiens	39-50
23136124-2	2013	The infrared spectra of the argon and nitrogen matrices doped with H2O2 and OCS or CS2 have been measured and analyzed.	Nitrogen	38-46	chorionic somatomammotropin hormone 2	Homo sapiens	83-86
23136124-9	2013	The solid nitrogen environment triggers the formation of the structures of C2v symmetry with a sulfur atom of OCS or CS2 directed toward the center of O-O bond of H2O2, stabilized by S   O interactions.	Nitrogen	10-18	chorionic somatomammotropin hormone 2	Homo sapiens	117-120
23634005-1	2013	In the title compound, [Co(C7H4ClO2)2(C5H5N)2(H2O)], the Co(II) atom is six-coordinated by three O atoms from a bidentate and a monodentate 4-chloro-benzoate ligand, two N atoms from two pyridine ligands and a water O atom, giving a distorted octa-hedral geometry.	Nitrogen	42-43	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	57-63
23485312-5	2013	On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid.	Nitrogen	42-43	glycophorin A (MNS blood group)	Homo sapiens	61-64
23485312-5	2013	On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid.	Nitrogen	42-43	glycophorin A (MNS blood group)	Homo sapiens	206-209
23485312-5	2013	On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid.	Nitrogen	116-117	glycophorin A (MNS blood group)	Homo sapiens	61-64
23485312-5	2013	On the other hand, laser-heating of the C=N polymer above 25 GPa further converts to a theoretically predicted 3D C-N network structure, evident from an emergence of new Raman nus(C-N) at 1404 cm(-1) at 25 GPa and the visual appearance of translucent solid.	Nitrogen	116-117	glycophorin A (MNS blood group)	Homo sapiens	206-209
23398593-10	2013	The desolvated Co(II)(pybz)2 can absorb several gases such as CO2, N2, H2, and CH4 and also vapors of methanol, ethanol, benzene, and cyclohexane.	Nitrogen	67-69	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	15-21
23381959-0	2013	Dinitrogen as double Lewis acid: structure and bonding of triphenylphosphinazine N2(PPh3)2.	Nitrogen	0-10	caveolin 1	Homo sapiens	84-88
23421481-5	2013	The new fac-[Re(CO)3(N(SO2R)dpa)]X structures provide the only examples for any metal with the sulfonamide as part of a noncyclic linear tridentate ligand and with a normal metal-to-nitrogen(tertiary sulfonamide) bond length.	Nitrogen	182-190	FA complementation group C	Homo sapiens	8-11
22821340-8	2013	The best condition for ammonia nitrogen removal from leachate was pH &gt;7.5, OM 23.58 %, Cu(II) &lt;5 mg L(-1), Zn(II) &lt;10 mg L(-1), and Pb(II) &lt;1 mg L(-1).	Nitrogen	31-39	submaxillary gland androgen regulated protein 3B	Homo sapiens	141-147
23295114-8	2013	The response in efficiency of N utilization (milk N yield/N intake) was positive to the substitution of a protein source by CM.	Nitrogen	30-31	Weaning weight-maternal milk	Bos taurus	45-49
23172977-5	2013	For 1 SD increase in SO(2) and oxides of nitrogen (NO(x)) concentrations in ambient air, a day before blood collection (lag(1)), we observed a significant increase in CRP (9.34 and 7.77%, respectively).	Nitrogen	41-49	C-reactive protein	Homo sapiens	167-170
22867529-5	2013	The docking results also showed that the formation of new H-bonds between the N-H of the ethylenediamine group linked to the 6-alkoxy site and Asp776/Cys773 in the binding pocket of EGFR makes compounds 19 (IC50=12.1+-1.6 nM) and 20 (IC50=13.6+-0.8 nM) the most potent EGFR inhibitors in this class and worthy of further modification to obtain more potent anticancer compounds.	Nitrogen	78-79	epidermal growth factor receptor	Homo sapiens	182-186
22867529-5	2013	The docking results also showed that the formation of new H-bonds between the N-H of the ethylenediamine group linked to the 6-alkoxy site and Asp776/Cys773 in the binding pocket of EGFR makes compounds 19 (IC50=12.1+-1.6 nM) and 20 (IC50=13.6+-0.8 nM) the most potent EGFR inhibitors in this class and worthy of further modification to obtain more potent anticancer compounds.	Nitrogen	78-79	epidermal growth factor receptor	Homo sapiens	269-273
23343309-5	2013	The results of the study on the quinoxaline   (H(2)O)(n) show that the preferred adducts in vacuo involve one, two, or three water molecules hydrogen bonded to the N atom and the neighboring H atom of the C(sp2)-H group.	Nitrogen	164-165	Sp2 transcription factor	Homo sapiens	205-210
23319596-8	2013	The N-glycosylation site at Asn-644 in the LOX catalytic domain is not conserved in human LOX (hLOX), although the LOX catalytic domain of hLOX shares ~50% identity and ~70% homology with hLOXL2.	Nitrogen	4-5	lysyl oxidase like 2	Homo sapiens	188-194
23215782-5	2013	Most notably, the NS exchange obliterated the usual IFN-induction-suppressing capacity associated with expression of full-size NS1 proteins, and hence functionally mimicked deletions in the NS1 gene.	Nitrogen	18-20	interferon alpha 1	Homo sapiens	52-55
23280693-7	2013	High expression of ABCG2 was also observed in cells with high p63 expression and low (&lt;0.7) N/C ratio; however, they were positive for Cx-43.	Nitrogen	95-96	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	19-24
23239109-0	2013	Sp2 C-dominant N-doped carbon sub-micrometer spheres with a tunable size: a versatile platform for highly efficient oxygen-reduction catalysts.	Nitrogen	15-16	Sp2 transcription factor	Homo sapiens	0-3
23291178-8	2013	We successfully synthesized milligram quantities of functional (15)N-labeled higher eukaryotic proteins, bovine pancreatic trypsin inhibitor (BPTI) and human lysozyme C (LYZ).	Nitrogen	67-68	lysozyme	Homo sapiens	170-173
23307693-0	2013	Nitrogen-doped sp2-hybridized carbon as a superior catalyst for selective oxidation.	Nitrogen	0-8	Sp2 transcription factor	Homo sapiens	15-18
23305235-13	2013	N-linked glycosylation aids proteolytic processing of GDNF.	Nitrogen	0-1	glial cell derived neurotrophic factor	Homo sapiens	54-58
23139156-9	2013	The data describe a novel mechanism by which hERG channel gating is modulated through physiologically and pathophysiologically relevant changes in N-glycosylation; reduced channel sialylation increases hERG channel activity during the action potential, thereby increasing the rate of action potential repolarization.	Nitrogen	147-148	ETS transcription factor ERG	Homo sapiens	45-49
23228448-2	2013	Here, foscarnet, an antiviral drug which inhibits several viral DNA polymerases by mimic pyrophosphate of nucleotides, was identified to interact with fibroblast growth factor 2 and stabilize the growth factor against tryptic digestion similar like the non-nitrogen containing bisphosphonates clodronate and etidronate that we have reported just recently as inhibitors of FGF-induced cell proliferation.	Nitrogen	257-265	fibroblast growth factor 2	Homo sapiens	151-177
23265881-4	2013	Modulation of activity at both receptors through substitution at the pyridone nitrogen led to the identification of potent dual AT1 antagonists/PPARgamma partial agonists.	Nitrogen	78-86	peroxisome proliferator activated receptor gamma	Homo sapiens	144-153
23139156-9	2013	The data describe a novel mechanism by which hERG channel gating is modulated through physiologically and pathophysiologically relevant changes in N-glycosylation; reduced channel sialylation increases hERG channel activity during the action potential, thereby increasing the rate of action potential repolarization.	Nitrogen	147-148	ETS transcription factor ERG	Homo sapiens	202-206
23268626-0	2013	Probing the nature of the Co(III) ion in corrins: comparison of reactions of aquacyanocobyrinic acid heptamethyl ester and aquacyano-stable yellow cobyrinic acid hexamethyl ester with neutral N-donor ligands.	Nitrogen	192-193	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	26-33
23340690-9	2013	Theoretical calculations further demonstrate that Cu(2+) ion binds to SS1 or SS2 in a slightly distorted tetragonal geometry with an S/N/2O environment and the minimum potential energy.	Nitrogen	135-136	major histocompatibility complex, class II, DR beta 1	Homo sapiens	70-73
23212906-2	2013	To elucidate the functional significance of N-glycosylation sites of STIM1, we created different mutations of asparagine-131 and asparagine-171.	Nitrogen	44-45	stromal interaction molecule 1	Homo sapiens	69-74
23230103-17	2013	In conclusion, a large reduction in dietary N led to reduced N excretion in urine and decreased milk production but did not affect N excretion in feces or microbial protein synthesis.	Nitrogen	44-45	Weaning weight-maternal milk	Bos taurus	96-100
23273919-2	2013	In yeast, attenuation of signaling by these kinases following nitrogen and/or carbon limitation activates the protein kinase Rim15, which orchestrates the initiation of a reversible cellular quiescence program to ensure normal chronological life span.	Nitrogen	62-70	protein kinase RIM15	Saccharomyces cerevisiae S288C	125-130
23184930-1	2013	Ure2 is a phosphoprotein and central negative regulator of nitrogen-responsive Gln3/Gat1 localization and their ability to activate transcription.	Nitrogen	59-67	solute carrier family 6 member 1	Homo sapiens	84-88
23184930-2	2013	This negative regulation is achieved by the formation of Ure2-Gln3 and -Gat1 complexes that are thought to sequester these GATA factors in the cytoplasm of cells cultured in excess nitrogen.	Nitrogen	181-189	solute carrier family 6 member 1	Homo sapiens	72-76
23268626-6	2013	Therefore, the distinction between the harder Co(III) in ACSYCbs and softer Co(III) in ACCbs, reported previously for anionic ligands, is maintained for neutral N-donor ligands.	Nitrogen	161-162	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	46-53
23282130-11	2013	Bond distances between the Co(III) and the axial nitrogen atoms were longest in the 2MeIm derivative as a result of distortion in the planar tetradentate ligand, and this was directly correlated to axial ligand lability and propensity toward exchange.	Nitrogen	49-57	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	27-34
23268626-6	2013	Therefore, the distinction between the harder Co(III) in ACSYCbs and softer Co(III) in ACCbs, reported previously for anionic ligands, is maintained for neutral N-donor ligands.	Nitrogen	161-162	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	76-83
23178939-0	2013	Coordinate regulation of N-glycosylation gene DPAGT1, canonical Wnt signaling and E-cadherin adhesion.	Nitrogen	25-26	cadherin 1	Homo sapiens	82-92
23117883-9	2013	N-linked glycosylations of CD44, particularly associated with the variant isoform CD44v6 after CD40L activation, seemed to facilitate hyaluronan recognition by CD44.	Nitrogen	0-1	CD40 ligand	Homo sapiens	95-100
23178939-1	2013	The metabolic pathway of protein N-glycosylation influences intercellular adhesion by affecting the composition and cytoskeletal association of E-cadherin protein complexes, or adherens junctions (AJs).	Nitrogen	33-34	cadherin 1	Homo sapiens	144-154
23178939-3	2013	N-glycosylation of E-cadherin is controlled by the DPAGT1 gene, a key regulator of the N-glycosylation pathway.	Nitrogen	0-1	cadherin 1	Homo sapiens	19-29
23178939-3	2013	N-glycosylation of E-cadherin is controlled by the DPAGT1 gene, a key regulator of the N-glycosylation pathway.	Nitrogen	87-88	cadherin 1	Homo sapiens	19-29
23178939-8	2013	Remarkably, a 2.4-fold increase in the DPAGT1 mRNA level resulted in increased N-glycosylation and reduced membrane localization of E-cadherin, coincident with dramatic changes in cell morphology.	Nitrogen	48-49	cadherin 1	Homo sapiens	132-142
23178939-9	2013	Lastly, we present evidence that N-glycosylation status of E-cadherin controls its antagonism of canonical Wnt signaling.	Nitrogen	33-34	cadherin 1	Homo sapiens	59-69
22836627-11	2013	In N-OSA-neg and N-OSA-pos groups, the positive differences D-SOD and D-TAS were observed, while Pre-OSA subjects presented negative differences.	Nitrogen	3-4	superoxide dismutase 1	Homo sapiens	62-65
23166320-9	2013	Evaluation of the p17 antagonist activity of a panel of biotechnological heparins derived by chemical sulfation of the Escherichia coli K5 polysaccharide revealed that the highly N,O-sulfated derivative prevents the binding of p17 to both heparin and CXCR1, thus inhibiting p17-driven chemotactic migration of human monocytes with an efficiency that is higher than those of heparin and HS.	Nitrogen	179-180	family with sequence similarity 72 member B	Homo sapiens	18-21
23166320-9	2013	Evaluation of the p17 antagonist activity of a panel of biotechnological heparins derived by chemical sulfation of the Escherichia coli K5 polysaccharide revealed that the highly N,O-sulfated derivative prevents the binding of p17 to both heparin and CXCR1, thus inhibiting p17-driven chemotactic migration of human monocytes with an efficiency that is higher than those of heparin and HS.	Nitrogen	179-180	family with sequence similarity 72 member B	Homo sapiens	227-230
23166320-9	2013	Evaluation of the p17 antagonist activity of a panel of biotechnological heparins derived by chemical sulfation of the Escherichia coli K5 polysaccharide revealed that the highly N,O-sulfated derivative prevents the binding of p17 to both heparin and CXCR1, thus inhibiting p17-driven chemotactic migration of human monocytes with an efficiency that is higher than those of heparin and HS.	Nitrogen	179-180	family with sequence similarity 72 member B	Homo sapiens	227-230
23316195-7	2012	The human PTX3 protein contains a single N-glycosylation site that is fully occupied by complex type oligosaccharides, mainly fucosylated and sialylated biantennary glycans.	Nitrogen	41-42	pentraxin 3	Homo sapiens	10-14
23151259-0	2013	Characterization of fibrinogen glycosylation and its importance for serum/plasma N-glycome analysis.	Nitrogen	81-82	fibrinogen beta chain	Homo sapiens	20-30
23151259-3	2013	Our aim was to characterize fibrinogen glycosylation in order to determine its contribution to differences between serum and plasma N-glycomes.	Nitrogen	132-133	fibrinogen beta chain	Homo sapiens	28-38
23649250-7	2013	Positive selection of methylamine-resistant mutants to obtain URE2 mutants was useful for improving nitrogen accumulation ability without recombinant techniques.	Nitrogen	100-108	glutathione peroxidase	Saccharomyces cerevisiae S288C	62-66
23200255-3	2013	N-alkylation of the pyridazinone ring markedly enhances potency against PDE4 but suppresses PDE3 inhibition.	Nitrogen	0-1	phosphodiesterase 4A	Homo sapiens	72-76
23844513-0	2013	[New synthesis of highly selective inhibitor of histone deacetylase 6--N-hydroxy-4-(2-methyl-1,2,3,4-tetrahydro-pyrido[4,3b]indol-5-ylmethyl)benzamide--Tubastatin A].	Nitrogen	71-73	histone deacetylase 6	Homo sapiens	48-69
23934569-7	2013	The calibration curve was linear in the concentration range of 0.5 to 15 muM and the detection limit was about 0.2 muM (Sb/N = 3).	Nitrogen	123-124	latexin	Homo sapiens	73-76
23934569-7	2013	The calibration curve was linear in the concentration range of 0.5 to 15 muM and the detection limit was about 0.2 muM (Sb/N = 3).	Nitrogen	123-124	latexin	Homo sapiens	115-118
23167757-0	2013	N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2).	Nitrogen	0-1	protein disulfide isomerase family A member 2	Homo sapiens	49-94
23495634-6	2013	However, pretreatment variation in NO3- availability, which reflected longer-term rates of nitrogen cycling, reduced community invasibility.	Nitrogen	91-99	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
23167757-0	2013	N-linked glycosylation modulates dimerization of protein disulfide isomerase family A member 2 (PDIA2).	Nitrogen	0-1	protein disulfide isomerase family A member 2	Homo sapiens	96-101
23167757-4	2013	Unlike most PDI family members, PDIA2 contains three predicted N-linked glycosylation sites.	Nitrogen	63-64	protein disulfide isomerase family A member 2	Homo sapiens	32-37
23167757-5	2013	By site-directed mutagenesis and enzymatic deglycosylation, we show here that all three Asn residues within the potential N-linked glycosylation sites of human PDIA2 (N127, N284 and N516) are glycosylated in human cells.	Nitrogen	122-123	protein disulfide isomerase family A member 2	Homo sapiens	160-165
22997242-7	2013	The tryptic TFF2 N-glycopeptide p34-39 (LSPHNR N-glycosylated with Fuc3Hex3HexNAc6) was identified by both ESI-tandem mass spectrometry and MALDI-post-source decay analysis.	Nitrogen	17-18	trefoil factor 2	Homo sapiens	12-16
23065485-10	2013	Specifically, our results confirm the effect of PYROXD2 polymorphisms on trimethylamine metabolism and suggest that a previously reported association of N-acetylated compounds with the ALMS1/NAT8 locus is driven by SNPs in the ALMS1 gene.	Nitrogen	153-154	N-acetyltransferase 8 (putative)	Homo sapiens	191-195
22997242-7	2013	The tryptic TFF2 N-glycopeptide p34-39 (LSPHNR N-glycosylated with Fuc3Hex3HexNAc6) was identified by both ESI-tandem mass spectrometry and MALDI-post-source decay analysis.	Nitrogen	17-18	general transcription factor IIH subunit 3	Homo sapiens	32-35
22997242-7	2013	The tryptic TFF2 N-glycopeptide p34-39 (LSPHNR N-glycosylated with Fuc3Hex3HexNAc6) was identified by both ESI-tandem mass spectrometry and MALDI-post-source decay analysis.	Nitrogen	44-45	trefoil factor 2	Homo sapiens	12-16
22997242-7	2013	The tryptic TFF2 N-glycopeptide p34-39 (LSPHNR N-glycosylated with Fuc3Hex3HexNAc6) was identified by both ESI-tandem mass spectrometry and MALDI-post-source decay analysis.	Nitrogen	44-45	general transcription factor IIH subunit 3	Homo sapiens	32-35
23475716-7	2013	This antibody, produced by SP2/0 murine myeloma cells, is N-glycosylated both in the Fc and Fab moieties, which have been shown to impact on safety and PK/PD and considered as a critical quality attribute.	Nitrogen	58-59	Sp2 transcription factor	Mus musculus	27-30
23225881-9	2013	We show that differential HA N-glycosylation markedly affected T cell activation and cytokine production in vitro and moderately influenced IL-2 production in vivo.	Nitrogen	29-30	interleukin 2	Homo sapiens	140-144
23201435-5	2013	When expressed alone, B1R is core N-glycosylated and forms oligomers localized intracellularly and on the cell surface.	Nitrogen	34-35	bradykinin receptor B1	Homo sapiens	22-25
23141831-9	2013	Moreover, milk-N/N-intake was higher, and milk urea nitrogen concentration and urinary urea-N excretion were lower for diets with normal levels of BFT than for AL or RC diets.	Nitrogen	15-16	Weaning weight-maternal milk	Bos taurus	10-14
23141831-9	2013	Moreover, milk-N/N-intake was higher, and milk urea nitrogen concentration and urinary urea-N excretion were lower for diets with normal levels of BFT than for AL or RC diets.	Nitrogen	52-60	Weaning weight-maternal milk	Bos taurus	42-46
23097434-0	2013	Molecular requirements for T cell recognition of N-myristoylated peptides derived from the simian immunodeficiency virus Nef protein.	Nitrogen	49-50	nef protein	Simian immunodeficiency virus	121-124
23097434-1	2013	We have recently isolated a rhesus macaque cytotoxic T cell line, 2N5.1, that specifically recognizes an N-myristoylated 5-mer peptide (C(14)-Gly-Gly-Ala-Ile-Ser [C14nef5]) derived from the simian immunodeficiency virus (SIV) Nef protein.	Nitrogen	67-68	nef protein	Simian immunodeficiency virus	226-229
23097434-7	2013	Given that N-myristoylation of the Nef protein occurs in the conserved motifs and is critical for viral pathogenesis, these observations predict that the lipopeptide-specific T cell response is difficult for viruses to avoid by simply introducing amino acid mutations.	Nitrogen	11-12	S100 calcium binding protein B	Homo sapiens	35-38
23098902-5	2013	Recombinant N-terminal His-tagged AGT1 purified from Escherichia coli was characterized with Ser, alanine (Ala) and Asn as amino acid donors and glyoxylate, pyruvate and hydroxypyruvate as organic acid acceptors.	Nitrogen	12-13	alanine:glyoxylate aminotransferase	Arabidopsis thaliana	34-38
23735696-6	2013	Estradiol benzoate (2 microg) increased basal mEPSC frequency and markedly diminished both the OFQ/N-induced activation of postsynaptic GIRK-1 channel currents and the presynaptic inhibition of glutamatergic neurotransmission.	Nitrogen	99-100	potassium inwardly-rectifying channel, subfamily J, member 3	Rattus norvegicus	136-142
23319116-8	2013	Large-scale production of highly pure N-myristoylated Arf6 could be achieved, which was fully functional for liposome-binding and EFA6-stimulated nucleotide exchange assays.	Nitrogen	38-39	pleckstrin and Sec7 domain containing	Homo sapiens	130-134
22578427-7	2013	Although the CrGLB1 transcript level increased in response to dark-light shift and nitrogen depletion, the level of mature CrPII protein did not change accordingly.	Nitrogen	83-91	uncharacterized protein	Chlamydomonas reinhardtii	13-19
23849337-5	2013	Among their putative toxic effects, Abeta oligomers are thought to act as pro-oxidants combining with redox-active metals to produce excessive reactive oxygen and nitrogen species.	Nitrogen	163-171	amyloid beta precursor protein	Homo sapiens	36-41
23405203-0	2013	N-glycoproteome of E14.Tg2a mouse embryonic stem cells.	Nitrogen	0-1	skull morphology 21	Mus musculus	19-22
23405203-3	2013	Using a highly selective glycopeptide-capture approach but ordinary liquid chromatography coupled mass spectrometry (LC-MS), we characterized the N-glycoproteins of E14.Tg2a cells and analyzed the close relationship between the obtained N-glycoproteome and cell-surface proteomes.	Nitrogen	146-147	skull morphology 21	Mus musculus	165-168
23405203-5	2013	In addition, our results provide a systematic view of the E14.Tg2a N-glycosylation, from which we discovered some striking patterns, including an evolutionarily preserved and maybe functionally selected complementarity between N-glycosylation and the transmembrane structure in protein sequences.	Nitrogen	67-68	skull morphology 21	Mus musculus	58-61
23405203-5	2013	In addition, our results provide a systematic view of the E14.Tg2a N-glycosylation, from which we discovered some striking patterns, including an evolutionarily preserved and maybe functionally selected complementarity between N-glycosylation and the transmembrane structure in protein sequences.	Nitrogen	227-228	skull morphology 21	Mus musculus	58-61
23041443-10	2013	The c-Met levels of the HSPN group were positively correlated with the blood urea nitrogen and serum creatinine levels (P &lt; 0.01).	Nitrogen	82-90	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	4-9
21837554-1	2013	Parallel acquisition NMR spectroscopy (PANSY) is used to detect simultaneously signals from up to four nuclear species, such as H-1, H-2, C-13, N-15, F-19 and P-31.	Nitrogen	21-22	ATPase H+ transporting V1 subunit E1	Homo sapiens	159-163
23217712-4	2012	The stress CDK Pho85 phosphorylates T36 upon nitrogen starvation or pheromone stimulation, destabilizing Cln3 to delay onset of S phase.	Nitrogen	45-53	cyclin CLN3	Saccharomyces cerevisiae S288C	105-109
23227926-7	2012	However, after MSCs were supplemented with Link N in chondrogenic differentiation medium, the quantity of GAG secreted into the culture medium, as well as aggrecan, COL2A1, and SOX9 gene expression, increased significantly.	Nitrogen	48-49	collagen type II alpha 1 chain	Homo sapiens	165-171
23227926-9	2012	When MSCs were cultured in osteogenic differentiation medium, Link N supplementation led to a significant decrease in mineral deposition, and alkaline phosphatase (ALP), OC, and RUNX2 gene expression.	Nitrogen	67-68	alkaline phosphatase, placental	Homo sapiens	142-162
23227926-9	2012	When MSCs were cultured in osteogenic differentiation medium, Link N supplementation led to a significant decrease in mineral deposition, and alkaline phosphatase (ALP), OC, and RUNX2 gene expression.	Nitrogen	67-68	alkaline phosphatase, placental	Homo sapiens	164-167
23227926-9	2012	When MSCs were cultured in osteogenic differentiation medium, Link N supplementation led to a significant decrease in mineral deposition, and alkaline phosphatase (ALP), OC, and RUNX2 gene expression.	Nitrogen	67-68	bone gamma-carboxyglutamate protein	Homo sapiens	170-172
23217569-7	2012	CONCLUSIONS: Sex is an important factor in disease progression and the response of SOD1 mice to a drug targeting a central enzyme in nitrogen metabolism, with female sex hormones playing a greater role than male sex hormones.	Nitrogen	133-141	superoxide dismutase 1, soluble	Mus musculus	83-87
23084275-3	2012	We incorporated an amine linker and optimized it on the nitrogen of the linker, thereby envisioning the enhancement of the PPAR alpha/gamma dual agonist activity together with altering the physicochemical properties.	Nitrogen	56-64	peroxisome proliferator activated receptor alpha	Mus musculus	123-133
23059753-3	2012	Based on a conformational analysis of DMT-Ams and tert-amines by NMR and X-ray diffraction methods, we concluded that a beta-alkyl group maintained in a gauche relationship with the nitrogen lone pair of tert-amines significantly hinders the approach of CDMT to the nitrogen.	Nitrogen	182-190	amyloid beta precursor protein	Homo sapiens	118-124
23059753-3	2012	Based on a conformational analysis of DMT-Ams and tert-amines by NMR and X-ray diffraction methods, we concluded that a beta-alkyl group maintained in a gauche relationship with the nitrogen lone pair of tert-amines significantly hinders the approach of CDMT to the nitrogen.	Nitrogen	266-274	amyloid beta precursor protein	Homo sapiens	118-124
22766194-3	2012	Although CD10 molecules of the human pre-B-cell line NALM-6 have 6 consensus N-glycosylation sites, three of them are known to be N-glycosylated by X-ray crystallography.	Nitrogen	53-54	membrane metalloendopeptidase	Homo sapiens	9-13
23105135-4	2012	Additionally, when challenged with mycobacterial agonists, macrophages from TLR1 602S/S individuals resist induction of host arginase-1, an enzyme that depletes cellular arginine stores required for the production of antimicrobial reactive nitrogen intermediates.	Nitrogen	240-248	toll like receptor 1	Homo sapiens	76-80
23593873-1	2012	To investigate the N-glycosylation characteristics of recombinant human erythropoietin (rhEPO) produced by an industrial Chinese hamster ovary (CHO) cell line that is currently used in a large scale manufacturing process, we cultured this cell strain in static mode.	Nitrogen	19-20	erythropoietin	Homo sapiens	72-86
23009203-3	2012	Structure-activity relationship studies revealed that adding substituents to the nitrogen atom of the urea so as to generate compounds bearing a branched linker group results in increased potency and selectivity for HDAC6.	Nitrogen	81-89	histone deacetylase 6	Mus musculus	216-221
23063155-1	2012	Milk urea nitrogen (MUN; mg of N/dL) has been shown to be related to excretion of urinary urea N (UUN; g of N/d) and total excretion of urinary N (UN; g of N/d) in dairy cows.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
23063155-1	2012	Milk urea nitrogen (MUN; mg of N/dL) has been shown to be related to excretion of urinary urea N (UUN; g of N/d) and total excretion of urinary N (UN; g of N/d) in dairy cows.	Nitrogen	22-23	Weaning weight-maternal milk	Bos taurus	0-4
23063155-5	2012	Milk was analyzed for MUN and protein content; urine was analyzed for total N, urea, and creatinine content; feces were analyzed for total N and DM content; and blood plasma was analyzed for urea and creatinine content.	Nitrogen	24-25	Weaning weight-maternal milk	Bos taurus	0-4
23275579-7	2012	Genetic and physiological studies together with RNA sequencing and metabolite analysis of TOR-suppressed lines revealed that TOR regulates development and life span in Arabidopsis by restructuring cell growth, carbon and nitrogen metabolism, gene expression, and rRNA and protein synthesis.	Nitrogen	221-229	target of rapamycin	Arabidopsis thaliana	90-93
23275579-7	2012	Genetic and physiological studies together with RNA sequencing and metabolite analysis of TOR-suppressed lines revealed that TOR regulates development and life span in Arabidopsis by restructuring cell growth, carbon and nitrogen metabolism, gene expression, and rRNA and protein synthesis.	Nitrogen	221-229	target of rapamycin	Arabidopsis thaliana	125-128
22766194-3	2012	Although CD10 molecules of the human pre-B-cell line NALM-6 have 6 consensus N-glycosylation sites, three of them are known to be N-glycosylated by X-ray crystallography.	Nitrogen	77-78	membrane metalloendopeptidase	Homo sapiens	9-13
22766194-4	2012	METHODS: In order to investigate the role of N-glycans in the full expression of NEP activity, we modified N-glycans by treatment of NALM6 cells with various glycosidases or alter each of the consensus N-glycosylation sites by generating site-directed mutagenesis and compared the NEP activities of the sugar-altered CD10 with those of intact CD10.	Nitrogen	45-46	membrane metalloendopeptidase	Homo sapiens	81-84
22766194-5	2012	RESULTS: CD10 of the human B-cell line NALM-6 was dominantly localized in raft microdomains and heterogeneously N-glycosylated.	Nitrogen	39-40	membrane metalloendopeptidase	Homo sapiens	9-13
22766194-7	2012	All of the three consensus sites of CD10 in HEK293 cells introduced with wild type-CD10 were confirmed to be N-glycosylated.	Nitrogen	109-110	membrane metalloendopeptidase	Homo sapiens	36-40
22766194-7	2012	All of the three consensus sites of CD10 in HEK293 cells introduced with wild type-CD10 were confirmed to be N-glycosylated.	Nitrogen	109-110	membrane metalloendopeptidase	Homo sapiens	83-87
22766194-9	2012	CONCLUSIONS: N-glycosylation at Asn(628) is essential not only for NEP activities, but also for surface expression.	Nitrogen	2-3	membrane metalloendopeptidase	Homo sapiens	67-70
23117589-2	2012	Some compounds were as active as tadalafil in inhibiting PDE5 and of better selectivity profile particularly versus PDE11A, the nature of the terminal ring and its nitrogen substituent are the main determinants of selectivity.	Nitrogen	164-172	phosphodiesterase 5A	Homo sapiens	57-61
22539085-4	2012	Using a murine leukemia model FBL3 with GM3 antigen as the target, it was shown that artificial GM3 N-phenylacetyl derivative (GM3NPhAc) elicited robust antigen-specific T cell-dependent immunity and that N-phenylacetyl-D-mannosamine (ManNPhAc) as the biosynthetic precursor of GM3NPhAc selectively glycoengineered cancer cells to express GM3NPhAc both in vitro and in vivo.	Nitrogen	100-101	F-box and leucine-rich repeat protein 2	Mus musculus	30-34
22949220-0	2012	Electrophoretically mediated microanalysis for characterization of the enantioselective CYP3A4 catalyzed N-demethylation of ketamine.	Nitrogen	105-106	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	88-94
22949220-2	2012	An EMMA method was developed to investigate the stereoselectivity of the CYP3A4-mediated N-demethylation of ketamine.	Nitrogen	89-90	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	73-79
22960125-3	2012	Mtl1 is N-glycosylated protein, highly O-mannosylated by Pmt1, Pmt4 and mostly by Pmt2.	Nitrogen	8-9	metallothionein 1X pseudogene 1	Homo sapiens	0-4
22982335-5	2012	The deduced protein possesses all the main features characteristic of known GILT proteins including the signature sequence CQHGX2ECX2NX4C spanning residues 117-132, CXXC motif at residues 72-75, one potential sites for N-linked glycosylation at residual positions 54.	Nitrogen	133-134	IFI30 lysosomal thiol reductase	Danio rerio	76-80
23061476-2	2012	Glycine (and glycine-N,N,O-d(3)) ttc/VIp was found to convert back to ttt/Ip in the dark by hydrogen-atom tunneling.	Nitrogen	21-22	vasoactive intestinal peptide	Homo sapiens	37-40
23095999-9	2012	Vulnerability to cavitation, measured as the xylem pressure inducing 50% loss of conductivity (P50), ranged from -1.71 MPa to -0.15 MPa in saplings subjected to drought and nitrogen fertilization, respectively.	Nitrogen	173-181	nuclear factor kappa B subunit 1	Homo sapiens	95-98
23001782-0	2012	Micro- and macroheterogeneity of N-glycosylation yields size and charge isoforms of human sex hormone binding globulin circulating in serum.	Nitrogen	33-34	sex hormone binding globulin	Homo sapiens	90-118
22832515-7	2012	Mice lacking C5aR were significantly protected from functional renal disease as assessed by blood urea nitrogen levels.	Nitrogen	103-111	complement component 5a receptor 1	Mus musculus	13-17
22966204-2	2012	The yeast general amino acid permease, Gap1, is ubiquitylated and downregulated when a good nitrogen source like ammonium is provided to cells growing on a poor nitrogen source.	Nitrogen	92-100	amino acid permease GAP1	Saccharomyces cerevisiae S288C	39-43
22966204-2	2012	The yeast general amino acid permease, Gap1, is ubiquitylated and downregulated when a good nitrogen source like ammonium is provided to cells growing on a poor nitrogen source.	Nitrogen	161-169	amino acid permease GAP1	Saccharomyces cerevisiae S288C	39-43
22966204-7	2012	We here show that on a poor nitrogen source, the Bul adaptors are phosphorylated in an Npr1-dependent manner and bound to 14-3-3 proteins that protect Gap1 against downregulation.	Nitrogen	28-36	amino acid permease GAP1	Saccharomyces cerevisiae S288C	151-155
22785177-3	2012	Compared to wild-type mice, cisplatin-treated IFN-gamma-deficient (IFN-gamma(-/-)) mice exhibited exaggerated histopathological changes with higher blood urea nitrogen and creatinine levels.	Nitrogen	159-167	interferon gamma	Mus musculus	46-55
22785177-3	2012	Compared to wild-type mice, cisplatin-treated IFN-gamma-deficient (IFN-gamma(-/-)) mice exhibited exaggerated histopathological changes with higher blood urea nitrogen and creatinine levels.	Nitrogen	159-167	interferon gamma	Mus musculus	67-76
23071334-2	2012	PRMT5 symmetrically di-methylates the two-terminal omega-guanidino nitrogens of arginine residues on substrate proteins.	Nitrogen	67-76	protein arginine methyltransferase 5	Homo sapiens	0-5
22984264-0	2012	N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane.	Nitrogen	0-1	solute carrier family 9 member A1	Homo sapiens	116-120
23001782-3	2012	Here, we perform a detailed site-specific characterization of the N- and O-linked glycosylation of serum-derived hSHBG.	Nitrogen	66-67	sex hormone binding globulin	Homo sapiens	113-118
23001782-5	2012	It was found that serum-derived hSHBG is N-glycosylated at Asn(351)  and Asn(367)  with average molar occupancies of 85.1 and 95.3%, respectively.	Nitrogen	41-42	sex hormone binding globulin	Homo sapiens	32-37
22921741-8	2012	The different stereochemistry of the N-acetyl group at position C(2) of mannosamine (MenA CPS) and glucosamine (MenX CPS) respectively might play a fundamental role in this susceptibility to polysaccharide chain degradation.	Nitrogen	37-38	ENAH actin regulator	Homo sapiens	85-89
23236605-1	2012	The mouse macrophage-derived apoptosis inhibitor of macrophage (AIM), which is incorporated into adipocytes and induces lipolysis by suppressing fatty acid synthase (FAS) activity, possesses three potential N-glycosylation sites.	Nitrogen	207-208	fatty acid synthase	Mus musculus	166-169
22796647-5	2012	Procyanidin C1 caused a significant increase in NO production from RAECs via phosphorylation of both eNOS and Akt, and the effect was completely inhibited by N(G)-monomethyl-l-arginine or combined treatment with iberiotoxin and the phosphatidylinositol 3-kinase (PI3K) specific inhibitor, wortmannin, as well as combined treatment with 2-APB and wortmannin.	Nitrogen	48-49	AKT serine/threonine kinase 1	Rattus norvegicus	110-113
22967898-0	2012	Determination of cathepsin V activity and intracellular trafficking by N-glycosylation.	Nitrogen	71-72	cathepsin V	Homo sapiens	17-28
22967898-2	2012	Cathepsin V contains two predicted N-glycosylation sites, but it has not been reported whether cathepsin V is glycosylated or not.	Nitrogen	35-36	cathepsin V	Homo sapiens	0-11
22967898-3	2012	In this study, we clarified the role of N-glycosylation of cathepsin V for its functions.	Nitrogen	40-41	cathepsin V	Homo sapiens	59-70
22967898-4	2012	We demonstrated that cathepsin V is N-glycosylated at both Asn(221) and Asn(292) using mass spectrometry and site-directed mutagenesis.	Nitrogen	36-37	cathepsin V	Homo sapiens	21-32
22967898-5	2012	N-glycosylation of cathepsin V was important for transportation to lysosome, secretion, and activity in HT1080 cells.	Nitrogen	0-1	cathepsin V	Homo sapiens	19-30
22967898-6	2012	These data demonstrated that functions of cathepsin V are controlled by N-glycosylation.	Nitrogen	72-73	cathepsin V	Homo sapiens	42-53
23351427-3	2012	Our purpose is to study the prophylactic effect of HS 5% infusion versus NS on serum IL-6 as an inflammatory &amp; IL-10 as an anti-inflammatory biomarker in CABG patients.	Nitrogen	73-75	interleukin 6	Homo sapiens	85-89
22967301-3	2012	Recently, the crystal structures of ATX were determined, but the means by which the nuclease-like domain and the N-glycosylation participate in the catalytic activity still remain undetermined.	Nitrogen	113-114	ectonucleotide pyrophosphatase/phosphodiesterase 2	Homo sapiens	36-39
22985023-7	2012	Moreover, (1)H and (19)F-NMR studies show that this pi-pi interaction promotes hydrogen transfer from [(NHC)AuH] to pyridyl N atom, resulting in C-F bond cleavage.	Nitrogen	25-26	AU RNA binding methylglutaconyl-CoA hydratase	Homo sapiens	108-111
23125582-1	2012	In the title compound, [Co(CH(3)CO(2))(C(18)H(24)N(6))]PF(6), the Co(II) atom is penta-coordinated in a distorted trigonal-bipyramidal geometry by four N atoms from a tripodal ligand and one O atom from a monodentate acetate ligand.	Nitrogen	49-50	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	66-72
22583412-2	2012	The presence of nitrogen (sp3) is favorable for decrease of the both endpoints; the presence of only one ring is also promotor for decrease of the both endpoints; however the presence of two or three rings is favorable for increase of mutagenicity and decrease of anticancer activity.	Nitrogen	16-24	Sp3 transcription factor	Homo sapiens	26-29
22761399-10	2012	Finally, the studies on KRAS-regulated N-glycoproteins revealed structural alterations in the core N-glycans of SEMA4B in KRAS-activated human bronchial epithelial cells and functional role of N-glycosylation of TIMP-1 in the regulation of lung adenocarcinoma A549 cell invasion.	Nitrogen	39-40	TIMP metallopeptidase inhibitor 1	Homo sapiens	212-218
22569921-5	2012	Functional studies were executed in yeast to confirm that the TdATG8 protein is functional, and showed that the TdAtg8 gene complements the atg8 ::kan MX yeast mutant strain grown under nitrogen deficiency.	Nitrogen	186-194	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	140-144
22936575-0	2012	Reductive cleavage of the Csp2-Csp3 bond of secondary benzyl alcohols: rhodium catalysis directed by N-containing groups.	Nitrogen	101-102	regulator of calcineurin 2	Homo sapiens	26-30
22761373-0	2012	N-linked glycosylation of GP5 of porcine reproductive and respiratory syndrome virus is critically important for virus replication in vivo.	Nitrogen	0-1	glycoprotein V platelet	Homo sapiens	26-29
22858143-1	2012	Introduction of a nitrogen atom into the benzene ring of a previously identified HCV replication (replicase) benzothiazole inhibitor 1, resulted in the discovery of the more potent pyridothiazole analogues 3.	Nitrogen	18-26	protein phosphatase 1 regulatory inhibitor subunit 1A	Homo sapiens	123-134
23073222-7	2012	MIFs calculated with the N1 (pyridinium nitrogen) and the DRY GRID probes in the AChE active site enabled us to establish the relationship between amino acid residues within AChE active site and the variables having high impact on models.	Nitrogen	40-48	acetylcholinesterase (Cartwright blood group)	Homo sapiens	81-85
23073222-7	2012	MIFs calculated with the N1 (pyridinium nitrogen) and the DRY GRID probes in the AChE active site enabled us to establish the relationship between amino acid residues within AChE active site and the variables having high impact on models.	Nitrogen	40-48	acetylcholinesterase (Cartwright blood group)	Homo sapiens	174-178
22761373-5	2012	However, the mutants carrying multiple mutations at N-linked glycosylation sites in GP5 had significantly reduced virus yields compared with the wild-type (wt) virus.	Nitrogen	52-53	glycoprotein V platelet	Homo sapiens	84-87
22761373-7	2012	These results suggest that the N-linked glycosylation of GP5 is critically important for virus replication in vivo.	Nitrogen	31-32	glycoprotein V platelet	Homo sapiens	57-60
22669605-5	2012	An expression analysis of the main regulatory and pathway genes showed that at conditions of higher concentrations of ammonium and total nitrogen, the expression levels of PAP1 and TT8 decreased, but the expression levels of LBD37, 38 and 39, three negative regulators of anthocyanin biosynthesis, increased.	Nitrogen	137-145	LOB domain-containing protein 37	Arabidopsis thaliana	225-230
22372734-3	2012	Expression of nucleoside transporters ENT1 and ENT3, together with nucleoside import, was increased upon nitrogen limitation.	Nitrogen	105-113	equilibrative nucleotide transporter 1	Arabidopsis thaliana	38-42
22740656-0	2012	Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells.	Nitrogen	73-74	DNA repair protein XRCC4	Cricetulus griseus	56-61
22669605-7	2012	In contrast, at conditions of lower concentrations of ammonium and total nitrogen, the expression levels of PAP1, TT8 and the main pathway genes increased, whereas those of LBD37, 38 and 39 decreased.	Nitrogen	73-81	LOB domain-containing protein 37	Arabidopsis thaliana	173-178
22982912-5	2012	A significant correlation was found between the ACE mRNA gene expression and the mean blood pressure, serum creatinine, blood urea nitrogen and 24-h urinary protein.	Nitrogen	131-139	angiotensin I converting enzyme	Homo sapiens	48-51
22571197-0	2012	TGF-beta sensitivity is determined by N-linked glycosylation of the type II TGF-beta receptor.	Nitrogen	38-39	transforming growth factor beta 1	Homo sapiens	0-8
22683714-6	2012	The same structural activity analogy was extended to organosulfur compounds and it was observed that compound with non-bonding nitrogen interactions, i.e. C-5 has significantly (p&lt;0.05) higher TPx like activity than C-6 and C-4.	Nitrogen	127-135	complement C4A	Rattus norvegicus	227-230
22525010-6	2012	The numbers of potential N-glycosylation sites are variable in major glycoprotein GP5 but are conserved in minor glycoproteins GP2, GP3 and GP4.	Nitrogen	25-26	glycoprotein V platelet	Homo sapiens	82-85
22525010-6	2012	The numbers of potential N-glycosylation sites are variable in major glycoprotein GP5 but are conserved in minor glycoproteins GP2, GP3 and GP4.	Nitrogen	25-26	glycoprotein 2	Homo sapiens	127-130
22692508-7	2012	In addition, TCL1-overexpressing CLL cells manufacture a distinctly different BCR, as we detected increased expression of membrane-bound IgM and altered N-linked glycosylation of Igalpha and Igbeta, which account for the hyperactive BCR in malignant CLL.	Nitrogen	153-154	T cell lymphoma breakpoint 1	Mus musculus	13-17
22904723-2	2012	In each mol-ecule, the Co(III) ion is coordinated by an O atom and an N atom from three bidentate 2,4-dichloro-6-(ethyl-imino-meth-yl)phenolate ligands in a slightly distorted octa-hedral environment.	Nitrogen	70-71	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	23-30
22904774-1	2012	In the title polymeric complex, [Co(NCS)(2){SC(NH(2))(2)}(2)](n), the asymmetric unit comprises a Co(II) ion, which is situated on an inversion centre, an N-bound thio-cyanate anion and a mu(2)-bridging thio-urea mol-ecule.	Nitrogen	36-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	98-104
22608534-6	2012	Finally, P9-2 was N-glycosylated and located at the plasma membrane in association with filopodia-like protrusions containing actin, suggesting a possible role in virus cell-to-cell movement and spread.	Nitrogen	18-19	advillin	Homo sapiens	9-13
22571197-0	2012	TGF-beta sensitivity is determined by N-linked glycosylation of the type II TGF-beta receptor.	Nitrogen	38-39	transforming growth factor beta 1	Homo sapiens	76-84
22571197-4	2012	In the present study, we show that inhibiting the N-linked glycosylation process successfully hinders binding of TGF-beta1 to TbetaRII and subsequently renders cells resistant to TGF-beta signalling.	Nitrogen	50-51	transforming growth factor beta 1	Homo sapiens	113-122
22571197-4	2012	In the present study, we show that inhibiting the N-linked glycosylation process successfully hinders binding of TGF-beta1 to TbetaRII and subsequently renders cells resistant to TGF-beta signalling.	Nitrogen	50-51	transforming growth factor beta 1	Homo sapiens	113-121
22571197-8	2012	Collectively, these findings demonstrate that N-linked glycosylation is essentially required for the successful cell surface transportation of TbetaRII, suggesting a novel mechanism by which the TGF-beta sensitivity can be regulated by N-linked glycosylation levels of TbetaRII.	Nitrogen	46-47	transforming growth factor beta 1	Homo sapiens	195-203
22571197-8	2012	Collectively, these findings demonstrate that N-linked glycosylation is essentially required for the successful cell surface transportation of TbetaRII, suggesting a novel mechanism by which the TGF-beta sensitivity can be regulated by N-linked glycosylation levels of TbetaRII.	Nitrogen	236-237	transforming growth factor beta 1	Homo sapiens	195-203
22537809-2	2012	In this study, we showed that N-linked glycosylation of GP2 is not essential for virus viability and none of the individual glycosylation sites in GP3 has a vital effect on the production of infectious virus.	Nitrogen	30-31	glycoprotein 2	Homo sapiens	56-59
22736280-6	2012	Furthermore, we found that the regulated GnT-IVa converts the heterogeneous N-glycosylated forms of CD147 in Hepa1-6 and Hca-F cells, and significantly changed the antennary oligosaccharide structures on CD147.	Nitrogen	76-77	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	41-48
22476944-3	2012	Much attention has focused on studies to understand aberrant functions of the ionotropic glutamate receptors, perturbation of calcium homeostasis, and toxic effects of oligomeric amyloid beta peptides (Abeta) which results in production of reactive oxygen and nitrogen species and signaling pathways, leading to mitochondrial dysfunction and synaptic impairments.	Nitrogen	260-268	amyloid beta precursor protein	Homo sapiens	179-191
22476944-3	2012	Much attention has focused on studies to understand aberrant functions of the ionotropic glutamate receptors, perturbation of calcium homeostasis, and toxic effects of oligomeric amyloid beta peptides (Abeta) which results in production of reactive oxygen and nitrogen species and signaling pathways, leading to mitochondrial dysfunction and synaptic impairments.	Nitrogen	260-268	amyloid beta precursor protein	Homo sapiens	202-207
22660841-5	2012	The objective of the current study was to determine whether the syndecan-4 GAG and N-glycosylated chains and the cytoplasmic domain functions through modulating focal adhesion formation and apoptosis.	Nitrogen	83-84	syndecan-4	Meleagris gallopavo	64-74
22742743-12	2012	These individuals share clinical features similar to those of congenital myasthenic syndrome due to GFPT1 mutations, and their disorder might be part of a larger subgroup comprising the congenital myasthenic syndromes that result from defects in the N-linked glycosylation pathway and that manifest through impaired neuromuscular transmission.	Nitrogen	250-251	glutamine--fructose-6-phosphate transaminase 1	Homo sapiens	100-105
22467853-0	2012	The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.	Nitrogen	121-122	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	4-29
22467853-0	2012	The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.	Nitrogen	121-122	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	39-44
22467853-1	2012	Protein N-glycosylation is an essential modification that occurs in all eukaryotes and is catalysed by the oligosaccharyltransferase (OST) in the endoplasmic reticulum.	Nitrogen	8-9	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	107-132
22467853-1	2012	Protein N-glycosylation is an essential modification that occurs in all eukaryotes and is catalysed by the oligosaccharyltransferase (OST) in the endoplasmic reticulum.	Nitrogen	8-9	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	134-137
22467853-7	2012	Thus, OST48 and DAD1 are global modulators of OST stability and hence N-glycosylation.	Nitrogen	70-71	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	6-11
22467853-7	2012	Thus, OST48 and DAD1 are global modulators of OST stability and hence N-glycosylation.	Nitrogen	70-71	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	6-9
22702952-1	2012	Zinc thiolate complexes containing N(2)S tridentate ligands were prepared to investigate their reactivity toward reactive nitrogen species, chemistry proposed to occur at the zinc tetracysteine thiolate site of nitric oxide synthase (NOS).	Nitrogen	35-40	nitric oxide synthase 2	Homo sapiens	211-232
22753898-6	2012	In their view, PSEN1 mediates the N-glycosylation of V0a1 in the endoplasmic reticulum (ER); consequently, PSEN deficiency prevents V0a1 glycosylation, compromising the delivery of unglycosylated V0a1 to lysosomes, ultimately impairing V-ATPase function and lysosomal acidification.	Nitrogen	18-19	Vacuolar H[+]-ATPase 26kD subunit	Drosophila melanogaster	236-244
22830360-1	2012	Glutamine synthetase (GS) is ubiquitously expressed in mammalian organisms and is a key enzyme in nitrogen metabolism.	Nitrogen	98-106	glutamate-ammonia ligase	Homo sapiens	0-20
22577142-2	2012	In eukaryotes, the major way to generate N-degrons is through arginylation by ATE1 arginyl-tRNA-protein transferases, which transfer Arg from aminoacyl-tRNA to N-terminal Asp and Glu (and Cys as well in mammals).	Nitrogen	41-42	arginyltransferase 1	Mus musculus	78-82
21916911-10	2012	Only baseline mean serum N-mid OC (15 2 +- 0 5 vs 13 0 +- 0 5 mug/l, P &lt; 0 05) and fasting plasma glucose (4 92 +- 0 04 vs 5 28 +- 0 07 mmol/l, P &lt; 0 05) were significantly different between the two groups.	Nitrogen	25-26	bone gamma-carboxyglutamate protein	Homo sapiens	31-33
22561245-11	2012	However the presence of N-linked sugar moiety was shown to be unimportant for tumor suppressive activity but was critically important for its immunoregulative activity which demonstrates that different molecular mechanisms are involved in these two types of biological functional activities attributed to AFP.	Nitrogen	24-25	alpha fetoprotein	Homo sapiens	305-308
22492205-0	2012	The essential endoplasmic reticulum chaperone Rot1 is required for protein N- and O-glycosylation in yeast.	Nitrogen	75-76	Rot1p	Saccharomyces cerevisiae S288C	46-50
22371257-13	2012	KEY MESSAGE: N-glycosylation pathway in tobacco plants could be genetically engineered to produce a tissue-protective cytokine, asialoerythropoietin (a desialylated form of human hormone erythropoietin).	Nitrogen	13-14	erythropoietin	Homo sapiens	134-148
22260463-5	2012	The rAAV-CYP2J2 gene delivery in vivo increased EET generation; attenuated the rise in blood pressure; and reduced the levels of proteinuria, serum creatinine, and blood urea nitrogen.	Nitrogen	175-183	cytochrome P450, family 2, subfamily j, polypeptide 4	Rattus norvegicus	9-15
22533353-5	2012	The methodic exploration of instrument parameters showed enhanced IM separation of Bcl-xL conformers by combining high wave heights and velocities with low helium and nitrogen flow rates while keeping a high He/N(2) flow rate ratio (&gt;3).	Nitrogen	167-175	BCL2 like 1	Homo sapiens	83-89
22549782-10	2012	We propose that NF-kappaB, modulated by increased [Ca(2+)](rest), is constitutively active in mdx myotubes, and this mechanism can account for iNOS overexpression and the increase in reactive nitrogen species that promote damage in dystrophic skeletal muscle cells.	Nitrogen	192-200	nuclear factor kappa B subunit 1	Homo sapiens	16-25
22533353-5	2012	The methodic exploration of instrument parameters showed enhanced IM separation of Bcl-xL conformers by combining high wave heights and velocities with low helium and nitrogen flow rates while keeping a high He/N(2) flow rate ratio (&gt;3).	Nitrogen	211-212	BCL2 like 1	Homo sapiens	83-89
22719317-2	2012	The tris-N,N"-chelated Co(III) atom, which is located on the threefold rotation axis, shows a distorted octa-hedral coordination.	Nitrogen	9-10	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	23-30
22481162-0	2012	The Arabidopsis ubiquitin ligases ATL31 and ATL6 control the defense response as well as the carbon/nitrogen response.	Nitrogen	100-108	RING/U-box superfamily protein	Arabidopsis thaliana	44-48
22511785-6	2012	Mutation of predicted N-glycosylation sites on SIRPalpha indicates that Sp-D binding is dependent on interactions with specific N-glycosylated residues on the membrane-proximal D3 domain of SIRPalpha.	Nitrogen	128-129	signal regulatory protein alpha	Homo sapiens	190-199
22381536-3	2012	N-glycosylated syncytin 1 precursor (73 kDa) is cleaved to surface-associated (SU) and transmembrane (TM) subunits.	Nitrogen	0-1	endogenous retrovirus group W member 1, envelope	Homo sapiens	15-25
22511785-6	2012	Mutation of predicted N-glycosylation sites on SIRPalpha indicates that Sp-D binding is dependent on interactions with specific N-glycosylated residues on the membrane-proximal D3 domain of SIRPalpha.	Nitrogen	22-23	signal regulatory protein alpha	Homo sapiens	47-56
22511785-6	2012	Mutation of predicted N-glycosylation sites on SIRPalpha indicates that Sp-D binding is dependent on interactions with specific N-glycosylated residues on the membrane-proximal D3 domain of SIRPalpha.	Nitrogen	22-23	signal regulatory protein alpha	Homo sapiens	190-199
22511785-6	2012	Mutation of predicted N-glycosylation sites on SIRPalpha indicates that Sp-D binding is dependent on interactions with specific N-glycosylated residues on the membrane-proximal D3 domain of SIRPalpha.	Nitrogen	128-129	signal regulatory protein alpha	Homo sapiens	47-56
22446043-6	2012	However, mutations at one or two N-glycosylation sites in the mature domain of the short form GDF-9 caused a loss in mature protein production.	Nitrogen	33-34	growth differentiation factor 9	Canis lupus familiaris	94-99
22654736-10	2012	The segregation of BCATm to astrocytes and BCKDC to neurons provides further support for the existence of a BCAA-dependent glial-neuronal nitrogen shuttle since the data show that BCKAs produced by glial BCATm must be exported to neurons.	Nitrogen	138-146	branched chain amino acid transaminase 2	Rattus norvegicus	204-209
22446043-7	2012	These results suggest that the prodomain and N-linked glycosylation of the mature domain regulate proper processing and secretion of canine GDF-9.	Nitrogen	45-46	growth differentiation factor 9	Canis lupus familiaris	140-145
22473784-5	2012	In turn, an n-3 deficient diet and fructose interventions disrupted insulin receptor signalling in hippocampus as evidenced by a decrease in phosphorylation of the insulin receptor and its downstream effector Akt.	Nitrogen	1-2	AKT serine/threonine kinase 1	Rattus norvegicus	209-212
22494190-0	2012	Integrative analysis of N-linked human glycoproteomic data sets reveals PTPRF ectodomain as a novel plasma biomarker candidate for prostate cancer.	Nitrogen	24-25	protein tyrosine phosphatase receptor type F	Homo sapiens	72-77
22361650-5	2012	Curiously, although GFP-Atg8 complemented the Deltaatg8 mutation, this protein made ATG8 cells more sensitive to nitrogen starvation, and less sensitive to leucine starvation.	Nitrogen	113-121	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	84-88
22272563-3	2012	The N-glycosylated chains and GAG chains are required for S4 to regulate turkey myogenic satellite cell proliferation.	Nitrogen	4-5	syndecan-4	Meleagris gallopavo	58-60
22272563-5	2012	S4 mutants with only one or without any N-glycosylated chains attached to the core protein with or without GAG chains were generated to study the function of N-glycosylated chains and the interaction between N-glycosylated chains and GAG chains.	Nitrogen	40-41	syndecan-4	Meleagris gallopavo	0-2
22459173-1	2012	Human cytochrome P450 2D6 (CYP2D6) is an enzyme of the CYP superfamily responsible for biotransformation of about 20% of drugs of known metabolism containing a basic nitrogen and a planar aromatic ring.	Nitrogen	166-174	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	6-25
22318986-6	2012	Furthermore, we show that P2X4 pore dilation is modulated by phosphoinositides (PIP(n) ) levels as it is inhibited by wortmannin, a blocker of PIP(n) synthesis, suggesting possible regulation by phospholipase C-coupled pathways.	Nitrogen	84-86	purinergic receptor P2X, ligand-gated ion channel 4	Mus musculus	26-30
22459173-1	2012	Human cytochrome P450 2D6 (CYP2D6) is an enzyme of the CYP superfamily responsible for biotransformation of about 20% of drugs of known metabolism containing a basic nitrogen and a planar aromatic ring.	Nitrogen	166-174	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	27-33
22354161-2	2012	Single crystal X-ray diffraction studies revealed that the Co(II) complex, {[Co(H(2)L)(H(2)O)(2)](NO(3))(2) 3H(2)O}(n) has a slightly distorted octahedral geometry around the central Co(II) ion; the ligand is coordinated through the ONO donor atoms to one Co(II) metal center and bridged through the pyridine nitrogen atom to another similar Co(II) center so as to form a one-dimensional polymeric unit.	Nitrogen	309-317	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	59-65
22812018-3	2012	Thus, targeting the Abeta plaques benzothiazole derivatives were synthesized with the scaffold of the most promising imaging agent PIB ([11C]-6-OH-BTA-1, [11C]-2-(4-(methylamino)phenyl)-6-hydroxybenzothiazole) and C = N as linker to study the binding characteristics with the target protein through surface plasmon resonance (SPR) technique.	Nitrogen	218-219	amyloid beta precursor protein	Homo sapiens	20-25
22427561-12	2012	CONCLUSIONS: GlcN inhibits ICAM-1 expression and functions by modulating the O-linked glycosylation of factors involved in NF-kappaB signaling and by reducing the N-linked glycosylation of TNF-alpha-induced ICAM-1 in ARPE-19 cells.	Nitrogen	2-3	nuclear factor kappa B subunit 1	Homo sapiens	123-132
22435751-3	2012	Such interaction between porphyrins of both BDP beta-Por(2) and BDP meso-Por(2) is dominant at room temperature, while the coordination of the nitrogen atoms of the triazole rings to the zinc ions of the porphyrins occurs at low temperature.	Nitrogen	143-151	AT-rich interaction domain 3B	Homo sapiens	44-47
22402605-0	2012	Fermi energy level tuning for high performance dye sensitized solar cells using sp2 selective nitrogen-doped carbon nanotube channels.	Nitrogen	94-102	Sp2 transcription factor	Homo sapiens	80-83
22383530-0	2012	Calcium-myristoyl Tug is a new mechanism for intramolecular tuning of calcium sensitivity and target enzyme interaction for guanylyl cyclase-activating protein 1: dynamic connection between N-fatty acyl group and EF-hand controls calcium sensitivity.	Nitrogen	190-191	guanylate cyclase activator 1A	Homo sapiens	124-161
22435751-3	2012	Such interaction between porphyrins of both BDP beta-Por(2) and BDP meso-Por(2) is dominant at room temperature, while the coordination of the nitrogen atoms of the triazole rings to the zinc ions of the porphyrins occurs at low temperature.	Nitrogen	143-151	AT-rich interaction domain 3B	Homo sapiens	64-67
22301678-8	2012	The former Co(II) complexes revealed a six-coordinate octahedron with one amine nitrogen, three pyridyl nitrogens, and two counter anions, and one coordinated anion, Cl(-), Br(-) and N(3)(-), forming intramolecular hydrogen bonds with two pivalamide N-H groups.	Nitrogen	80-88	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	11-17
22446090-3	2012	Here we report that N-methylation of 1a greatly increases its potency and results in excellent selectivity for SIRT2 over SIRT1 and SIRT3 isoforms.	Nitrogen	20-21	sirtuin 3	Homo sapiens	132-137
22301678-8	2012	The former Co(II) complexes revealed a six-coordinate octahedron with one amine nitrogen, three pyridyl nitrogens, and two counter anions, and one coordinated anion, Cl(-), Br(-) and N(3)(-), forming intramolecular hydrogen bonds with two pivalamide N-H groups.	Nitrogen	104-113	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	11-17
22301678-9	2012	On the other hand, the latter Co(II) complexes showed a seven-coordinate face-capped octahedron with one amine nitrogen, three pyridyl nitrogens, two pivalamide carbonyl oxygens and MeCN or MeOH.	Nitrogen	111-119	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	30-36
22385476-9	2012	The N-acetyl analogue is human TLR2-specific, with its potency comparable to that of PAM(2)CS.	Nitrogen	4-5	toll like receptor 2	Homo sapiens	31-35
22301678-9	2012	On the other hand, the latter Co(II) complexes showed a seven-coordinate face-capped octahedron with one amine nitrogen, three pyridyl nitrogens, two pivalamide carbonyl oxygens and MeCN or MeOH.	Nitrogen	135-144	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	30-36
22411760-2	2012	The resulting PANI/SBA-15 is capable of chelating Co(II) ions, presumably via its nitrogen atoms on PANI/diamine groups.	Nitrogen	82-90	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	50-56
22471764-8	2012	Functional analysis showed that Tkt1 confers very little transketolase activity but is involved in peptide nitrogen metabolism.	Nitrogen	107-115	transketolase	Homo sapiens	32-36
22343626-1	2012	We present a systematic structural optimization of uncharged but ionizable N-substituted 2-hydroxyiminoacetamido alkylamine reactivators of phosphylated human acetylcholinesterase (hAChE) intended to catalyze the hydrolysis of organophosphate (OP)-inhibited hAChE in the CNS.	Nitrogen	75-76	acetylcholinesterase (Cartwright blood group)	Homo sapiens	181-186
22343626-1	2012	We present a systematic structural optimization of uncharged but ionizable N-substituted 2-hydroxyiminoacetamido alkylamine reactivators of phosphylated human acetylcholinesterase (hAChE) intended to catalyze the hydrolysis of organophosphate (OP)-inhibited hAChE in the CNS.	Nitrogen	75-76	acetylcholinesterase (Cartwright blood group)	Homo sapiens	258-263
22332732-4	2012	TLS-dependent repair of ICLs formed between the exocyclic nitrogens of deoxyguanosines (N(2)-dG) can result in low-frequency base substitutions, predominantly G to T transversions.	Nitrogen	58-67	FUS RNA binding protein	Homo sapiens	0-3
22476151-4	2012	The N-glycosylic bonds of both conformers adopt similar anti conformations, with chi = -168.02 (12)  for conformer (I-1) and chi = -159.08 (12)  for conformer (I-2).	Nitrogen	4-5	protein phosphatase 1 regulatory inhibitor subunit 1A	Homo sapiens	116-119
22154009-0	2012	The effect of VEGF-immobilized nickel-free high-nitrogen stainless steel on viability and proliferation of vascular endothelial cells.	Nitrogen	48-56	vascular endothelial growth factor A	Homo sapiens	14-18
22527961-3	2012	Macrocycles with a basic nitrogen in the linker form a salt bridge with Asp86 in CDK2 and Asp698 in FLT3.	Nitrogen	25-33	fms related receptor tyrosine kinase 3	Homo sapiens	100-104
22262569-1	2012	3,4-Bis(1H-5-tetrazolyl)furoxan (H(2)BTF, 2) and its monoanionic salts that contain nitrogen-rich cations were readily synthesized and fully characterized by multinuclear NMR ((1)H, (13)C) and IR spectroscopy, differential scanning calorimetry (DSC), and elemental analyses.	Nitrogen	84-92	butyrophilin subfamily 2 member A2	Homo sapiens	37-43
22386260-3	2012	When their ability to inhibit Pim kinase activities were evaluated in in vitro assays, we observed that this nitrogen atom can be substituted without loss of Pim-1 and Pim-3 inhibitory potencies.	Nitrogen	109-117	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	30-33
22405770-0	2012	Temperature dependent N-glycosylation of plasma membrane heat shock protein Hsp30p in Saccharomyces cerevisiae.	Nitrogen	22-23	Hsp30p	Saccharomyces cerevisiae S288C	76-82
22405770-2	2012	Although Hsp30p contains a potential N-glycosylation consensus sequence (Asn(2)-Asp(3)-Thr(4)), whether it is actually N-glycosylated has not been verified.	Nitrogen	37-38	Hsp30p	Saccharomyces cerevisiae S288C	9-15
22405770-3	2012	Here we demonstrate that N-glycosylation is induced at Asn(2) of Hsp30p by severe heat shock, ethanol stress, and acetic acid stress.	Nitrogen	25-26	Hsp30p	Saccharomyces cerevisiae S288C	65-70
22361134-5	2012	Molecular modeling studies employing compound 20 showed that the phenyl CF(3) substituent attached to the CN spacer is positioned near the secondary pocket of the COX-2 active site, the CN nitrogen atom is hydrogen bonded (N   NH=2.85 A) to the H90 residue, and the indole N-1 benzoyl is positioned in a hydrophobic pocket of the COX-2 active site near W387.	Nitrogen	189-197	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	163-168
22365690-6	2012	Furthermore, N-glycosylation site ratios on serum haptoglobin (Hp) beta chain in healthy individuals as well as patients with hepatitis B virus (HBV), liver cirrhosis (LC) and hepatocellular carcinoma (HCC) were quantified to validate the novel "iTRAQ plus (18)O" method.	Nitrogen	13-14	haptoglobin	Homo sapiens	50-61
22266675-4	2012	Trioctylamine molecules undergo C-N bond cleavage to form octylamine via the redox reaction between the Co(III) and trioctylamine.	Nitrogen	34-35	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	104-111
22246635-2	2012	This study shows that dissimilatory nitrate reduction to ammonium (DNRA) process, where nitrogen is not removed but instead recycled in the system, dominates nitrate reduction in low oxygen conditions (O(2) &lt;110 muM), which have been persistent in the central Gulf of Finland during the past decade.	Nitrogen	88-96	latexin	Homo sapiens	215-218
22159084-0	2012	Role of N-glycosylation in cell surface expression and protection against proteolysis of the intestinal anion exchanger SLC26A3.	Nitrogen	8-9	solute carrier family 26 member 3	Homo sapiens	120-127
22159084-7	2012	Deglycosylation of SLC26A3 causes depression of transport activity compared with wild-type, although robust intracellular pH changes were still observed, suggesting that N-glycosylation is not absolutely necessary for transport activity.	Nitrogen	170-171	solute carrier family 26 member 3	Homo sapiens	19-26
22159084-13	2012	In conclusion, our data indicate that N-glycosylation of SLC26A3 is important for cell surface expression and for protection from proteolytic degradation that may contribute to the understanding of pathogenesis of congenital disorders of glycosylation.	Nitrogen	38-39	solute carrier family 26 member 3	Homo sapiens	57-64
22582156-6	2012	The human N-glycosylation site was predominantly conserved among other mammalian GPIHBP1 proteins except cow, dog and pig.	Nitrogen	10-11	glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1	Homo sapiens	81-88
22436226-8	2012	A consistent (in Experiment 4 only as tendency) higher AA-N/total N ratio (on average 17.5%) was observed in SAB than in LAB.	Nitrogen	58-59	SH3 domain binding protein 5	Homo sapiens	109-112
21915762-2	2012	The overproduction of nitrogen species derived from inducible nitric oxide synthase (iNOS), its enzyme, and interleukine-1 beta (IL-1beta), and inflammatory cytokine have been implicated in immune responses.	Nitrogen	22-30	nitric oxide synthase 2	Rattus norvegicus	52-83
21915762-2	2012	The overproduction of nitrogen species derived from inducible nitric oxide synthase (iNOS), its enzyme, and interleukine-1 beta (IL-1beta), and inflammatory cytokine have been implicated in immune responses.	Nitrogen	22-30	nitric oxide synthase 2	Rattus norvegicus	85-89
21915762-2	2012	The overproduction of nitrogen species derived from inducible nitric oxide synthase (iNOS), its enzyme, and interleukine-1 beta (IL-1beta), and inflammatory cytokine have been implicated in immune responses.	Nitrogen	22-30	interleukin 1 beta	Rattus norvegicus	129-137
22372551-4	2012	All four contain planar, aromatic groups as well as basic nitrogens common to CYP2D6 substrates.	Nitrogen	58-67	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	78-84
22187487-10	2012	The molecular docking study showed that the N-ethyl moiety of CP-945,598 can access to the heme iron-oxo of CYP3A4 in an energetically favored orientation.	Nitrogen	44-45	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	108-114
22247264-0	2012	The Ustilago maydis Nit2 homolog regulates nitrogen utilization and is required for efficient induction of filamentous growth.	Nitrogen	43-51	nitrilase 2	Zea mays	20-24
22247264-4	2012	We have identified the Nit2 homolog in the basidiomycetous phytopathogen Ustilago maydis and show that it is a major, but not the exclusive, positive regulator of nitrogen utilization.	Nitrogen	163-171	nitrilase 2	Zea mays	23-27
22247264-5	2012	By transcriptome analysis of sporidia grown on artificial media devoid of favored nitrogen sources, we show that only a subset of nitrogen-responsive genes are regulated by Nit2, including the Gal4-like transcription factor Ton1 (a target of Nit2).	Nitrogen	130-138	nitrilase 2	Zea mays	173-177
22247264-5	2012	By transcriptome analysis of sporidia grown on artificial media devoid of favored nitrogen sources, we show that only a subset of nitrogen-responsive genes are regulated by Nit2, including the Gal4-like transcription factor Ton1 (a target of Nit2).	Nitrogen	130-138	nitrilase 2	Zea mays	242-246
22106171-1	2012	Itraconazole (ITZ) is a mixture of four cis-stereoisomers that inhibit CYP3A4 potently and coordinate CYP3A4 heme via the triazole nitrogen.	Nitrogen	131-139	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	71-77
22106171-1	2012	Itraconazole (ITZ) is a mixture of four cis-stereoisomers that inhibit CYP3A4 potently and coordinate CYP3A4 heme via the triazole nitrogen.	Nitrogen	131-139	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	102-108
22247264-6	2012	Ustilagic acid biosynthesis is not under the control of Nit2, while nitrogen starvation-induced filamentous growth is largely dependent on functional Nit2.	Nitrogen	68-76	nitrilase 2	Zea mays	150-154
22224587-0	2012	Flexible FET-type VEGF aptasensor based on nitrogen-doped graphene converted from conducting polymer.	Nitrogen	43-51	vascular endothelial growth factor A	Homo sapiens	18-22
22140267-4	2012	Consistent with this, gp130 protein in resting BMMC was not on the cell surface to a measurable degree but was found intracellularly, and data are consistent with incompletely processed N-linked glycosylation.	Nitrogen	186-187	interleukin 6 signal transducer	Mus musculus	22-27
22117783-4	2012	CLEC-1 protein displayed N-linked glycosylation and formed dimers.	Nitrogen	25-26	C-type lectin domain family 1 member A	Homo sapiens	0-6
21890503-8	2012	In general, a functional association was found between the glycosaminoglycan and N-glycosylated chains attached to the central core proteins of syndecan-4 and glypican-1 affecting their regulation of muscle cell proliferation, differentiation, and FGF2 responsiveness.	Nitrogen	81-82	fibroblast growth factor 2	Homo sapiens	248-252
22805832-8	2012	Furthermore, differences were observed in the expression of genes which have been partially associated to nitrogen, as in the case of ZRT1 and ATO2.	Nitrogen	106-114	high-affinity Zn(2+) transporter ZRT1	Saccharomyces cerevisiae S288C	134-138
22805832-8	2012	Furthermore, differences were observed in the expression of genes which have been partially associated to nitrogen, as in the case of ZRT1 and ATO2.	Nitrogen	106-114	putative ammonium permease ATO2	Saccharomyces cerevisiae S288C	143-147
22262650-2	2012	In the case of SREBP-2, these effects were correlated with the altered N-linked glycosylation of subtilisin/kexin-like isozyme-1 (SKI-1), the protease responsible for SREBP-2 processing under sterol-limiting conditions.	Nitrogen	71-72	membrane-bound transcription factor site-1 protease	Cricetulus griseus	97-128
21924301-8	2012	In most cases, substitution of carbon with nitrogen and oxygen was related to increased compound degradation in comparison to unalkylated and sulphur- or unsubstituted PAH with a similar ring number.The obtained results indicate that GC2/MS can be employed for the rapid assessment of a large variety of structurally heterogeneous environmental contaminants.	Nitrogen	43-51	solute carrier family 25 member 18	Homo sapiens	234-237
22137605-2	2012	AtNRT2.1 expression plays a key role in the regulation of AtAMT1.1 expression and in the NH(4)(+) ion influx, differentiating the nitrogen source, and particularly, the lack of it.	Nitrogen	130-138	nitrate transporter 2:1	Arabidopsis thaliana	0-8
22137605-3	2012	Nitrogen starvation produces a compensatory effect by AtAMT1.1 when there is an absence of the AtNRT2.1 gene.	Nitrogen	0-8	nitrate transporter 2:1	Arabidopsis thaliana	95-103
22137605-4	2012	Our results also show that, in the atnrt2 mutant lacking both AtNRT2.1 and AtNRT2.2, gene functions present different kinetic parameters on the NH(4)(+) ion influx mediated by the HATS, according to the source and availability of nitrogen.	Nitrogen	230-238	nitrate transporter 2:1	Arabidopsis thaliana	62-70
22262650-2	2012	In the case of SREBP-2, these effects were correlated with the altered N-linked glycosylation of subtilisin/kexin-like isozyme-1 (SKI-1), the protease responsible for SREBP-2 processing under sterol-limiting conditions.	Nitrogen	71-72	membrane-bound transcription factor site-1 protease	Cricetulus griseus	130-135
22346895-2	2012	The coordination geometry of the Pb(II) atom is defined by one N and six O atoms, as well as a stereochemically active lone pair of electrons, and is based on a Psi-dodeca-hedron.	Nitrogen	63-64	submaxillary gland androgen regulated protein 3B	Homo sapiens	33-39
22101058-6	2012	Both, chiA abundance and chitinase activity correlated well with organic carbon, nitrogen, and concentrations of particulate GlcN.	Nitrogen	81-89	chitinase acidic	Homo sapiens	6-10
27009655-4	2012	Urease and glutamine synthetase (GS) activities varied with nitrogen source in a manner consistent with regulation by cellular nitrogen status via NtcA (rather than by external availability of nitrogen) in all three strains and indicated that each strain experienced some degree of nitrogen insufficiency during growth on nitrate.	Nitrogen	60-68	glutamate-ammonia ligase	Homo sapiens	11-31
22360887-5	2012	Expression of ZmTIP4;4 was significantly increased in roots and expanded leaves under nitrogen starvation, while those of ZmNIP2;1 and ZmNIP2;4 remained unaffected.	Nitrogen	86-94	aquaporin TIP4-4	Zea mays	14-22
22345010-6	2012	However, compared with CD4 extracellular domain D1 of human, CD4 D1 surface of tree shrews showed more negative charges, and more two N-glycosylation sites, which may affect antibody binding.	Nitrogen	134-135	CD4 molecule	Homo sapiens	61-64
22159026-5	2012	Nitrogen bubbles were consistently removed at a rate of 0.14 muL min(-1).	Nitrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	65-71
22159026-9	2012	Scalability of the design was demonstrated by realizing eight parallel traps at a total removal rate of 0.9 muL min(-1) (measured for nitrogen).	Nitrogen	134-142	CD59 molecule (CD59 blood group)	Homo sapiens	112-118
22395466-7	2012	The hypothesis that inactivation of HNF1A promotes branching of glycans was supported by the analysis of plasma N-glycomes in 61 patients with inactivating mutations in HNF1A, where the increase in plasma glycan branching was also observed.	Nitrogen	37-38	HNF1 homeobox A	Homo sapiens	169-174
27009655-4	2012	Urease and glutamine synthetase (GS) activities varied with nitrogen source in a manner consistent with regulation by cellular nitrogen status via NtcA (rather than by external availability of nitrogen) in all three strains and indicated that each strain experienced some degree of nitrogen insufficiency during growth on nitrate.	Nitrogen	60-68	glutamate-ammonia ligase	Homo sapiens	33-35
27009655-4	2012	Urease and glutamine synthetase (GS) activities varied with nitrogen source in a manner consistent with regulation by cellular nitrogen status via NtcA (rather than by external availability of nitrogen) in all three strains and indicated that each strain experienced some degree of nitrogen insufficiency during growth on nitrate.	Nitrogen	127-135	glutamate-ammonia ligase	Homo sapiens	33-35
27009655-4	2012	Urease and glutamine synthetase (GS) activities varied with nitrogen source in a manner consistent with regulation by cellular nitrogen status via NtcA (rather than by external availability of nitrogen) in all three strains and indicated that each strain experienced some degree of nitrogen insufficiency during growth on nitrate.	Nitrogen	127-135	glutamate-ammonia ligase	Homo sapiens	33-35
27009655-4	2012	Urease and glutamine synthetase (GS) activities varied with nitrogen source in a manner consistent with regulation by cellular nitrogen status via NtcA (rather than by external availability of nitrogen) in all three strains and indicated that each strain experienced some degree of nitrogen insufficiency during growth on nitrate.	Nitrogen	127-135	glutamate-ammonia ligase	Homo sapiens	33-35
22158677-5	2012	Despite a high and constitutive NRT2.1 transcript accumulation in the roots, the HATS activity was still down-regulated in the 35S::NRT2.1 transformants in response to repressive nitrogen or dark treatments that strongly reduce NRT2.1 transcription and NO(3)(-) HATS activity in the wild type.	Nitrogen	179-187	nitrate transporter 2:1	Arabidopsis thaliana	132-138
22158677-5	2012	Despite a high and constitutive NRT2.1 transcript accumulation in the roots, the HATS activity was still down-regulated in the 35S::NRT2.1 transformants in response to repressive nitrogen or dark treatments that strongly reduce NRT2.1 transcription and NO(3)(-) HATS activity in the wild type.	Nitrogen	179-187	nitrate transporter 2:1	Arabidopsis thaliana	132-138
22158760-6	2012	We demonstrate that modifying environmental conditions that stimulate the derepression of the NRT2.1 gene influences resistance to Pst independently of the total level of endogenous nitrogen.	Nitrogen	182-190	nitrate transporter 2:1	Arabidopsis thaliana	94-98
22172011-4	2012	For all three inhibitors, including both CHS orientations, the conserved interaction between the 4-keto group of the flavonoid and the backbone V101 nitrogen of CDK6 was strongly detected.	Nitrogen	149-157	cyclin dependent kinase 6	Homo sapiens	161-165
22142473-3	2012	Here, we show that in GI-ME-N cells, BSO activates Nrf2 and up-regulates heme oxygenase-1 (HO-1).	Nitrogen	28-29	NFE2 like bZIP transcription factor 2	Homo sapiens	51-55
22129786-3	2012	Pig CD11b cDNA sequence contains an ORF of 3459 nucleotides that encodes a deduced polypeptide of 1152 amino acid residues that share with CD11b from other species: High % amino acid identity, common domains (alpha-I, Ca(++) binding, MIDAS), N-glycosylation sites, and the seven FG-GAP tandem repeats.	Nitrogen	12-13	integrin alpha-M	Sus scrofa	4-9
22129786-3	2012	Pig CD11b cDNA sequence contains an ORF of 3459 nucleotides that encodes a deduced polypeptide of 1152 amino acid residues that share with CD11b from other species: High % amino acid identity, common domains (alpha-I, Ca(++) binding, MIDAS), N-glycosylation sites, and the seven FG-GAP tandem repeats.	Nitrogen	12-13	integrin alpha-M	Sus scrofa	139-144
21956654-1	2012	The use of intravenous nitrogen-containing bisphosphonates (N-BPs) is associated with the appearance of an acute phase response (APR) in a proportion of the patients for reasons that are poorly understood.	Nitrogen	23-31	phorbol-12-myristate-13-acetate-induced protein 1	Homo sapiens	129-132
21939780-10	2012	These data indicated that the syndecan-4 cytoplasmic domain and the GAG and N-glycosylated chains are critical in syndecan-4 regulating satellite cell proliferation, responsiveness to FGF2, and PKCalpha cell membrane localization.	Nitrogen	76-77	syndecan-4	Meleagris gallopavo	114-124
22100612-5	2012	PNGase F digestion confirmed that the higher molecular mass of the serum AAT was caused by N-glycosylation.	Nitrogen	1-2	serpin family A member 1	Homo sapiens	73-76
21899441-1	2012	The congenital disorder of glycosylation (CDG)-Ic (ALG6-CDG, CDG-Ic) is caused by mutations in the hALG6 gene that encodes the N-glycosylation pathway enzyme, alpha-1,3-glucosyltransferase (NP_037471.2).	Nitrogen	127-128	ALG6 alpha-1,3-glucosyltransferase	Homo sapiens	51-55
21899441-1	2012	The congenital disorder of glycosylation (CDG)-Ic (ALG6-CDG, CDG-Ic) is caused by mutations in the hALG6 gene that encodes the N-glycosylation pathway enzyme, alpha-1,3-glucosyltransferase (NP_037471.2).	Nitrogen	127-128	ALG6 alpha-1,3-glucosyltransferase	Homo sapiens	99-104
22024534-3	2012	To gain insights into the function of XYLT in the plant N-glycosylation pathway, we examined the acceptor substrate specificity of recombinant Arabidopsis XYLT (AtXYLT) using 2-aminopyridine-labeled N-glycans as the substrates and confirmed the N-glycans of Arabidopsis xylt mutant.	Nitrogen	56-57	beta-1,2-xylosyltransferase	Arabidopsis thaliana	38-42
22024534-3	2012	To gain insights into the function of XYLT in the plant N-glycosylation pathway, we examined the acceptor substrate specificity of recombinant Arabidopsis XYLT (AtXYLT) using 2-aminopyridine-labeled N-glycans as the substrates and confirmed the N-glycans of Arabidopsis xylt mutant.	Nitrogen	56-57	beta-1,2-xylosyltransferase	Arabidopsis thaliana	155-159
21864297-4	2012	Using a knockin mouse model (G/G mice; mice homozygous for the 112G allele of MOPR) that possesses the equivalent nucleotide/amino acid substitution (A112G; N38D) of the A118G SNP in the hMOPR gene, we investigated the N-linked glycosylation status of thalamic and striatal MOPR in G/G mice compared with A/A mice (wild-type mice homozygous for the 112A allele of MOPR).	Nitrogen	157-158	opioid receptor, mu 1	Mus musculus	78-82
22101009-0	2012	Nitrogen dioxide oxidizes mitochondrial cytochrome c.	Nitrogen	0-8	cytochrome c, somatic	Homo sapiens	40-52
22888341-0	2012	Effect of non-anticoagulant N-desulfated heparin on basic fibroblast growth factor expression, angiogenesis, and metastasis of gastric carcinoma in vitro and in vivo.	Nitrogen	28-29	fibroblast growth factor 2	Homo sapiens	52-82
23145130-3	2012	By altering the rearing environment for fruit flies, Drosophila melanogaster, we produced high quality flies containing more nitrogen and protein and less lipid than low quality fruit flies.	Nitrogen	125-133	proliferation disrupter	Drosophila melanogaster	81-85
22266900-1	2012	The oligosaccharyltransferase (OST) complex catalyses the N-glycosylation of polypeptides entering the endoplasmic reticulum, a process essential for the productive folding and trafficking of many secretory and membrane proteins.	Nitrogen	58-59	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	4-29
22266900-1	2012	The oligosaccharyltransferase (OST) complex catalyses the N-glycosylation of polypeptides entering the endoplasmic reticulum, a process essential for the productive folding and trafficking of many secretory and membrane proteins.	Nitrogen	58-59	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	31-34
23513691-3	2012	In fact, nitrogen deposition not only leads to increased soil total N content, but also changes in the NH4(+)-N content, NO3(-)-N content and pH, as well as changes in the heterogeneity of the four indexes.	Nitrogen	9-17	NBL1, DAN family BMP antagonist	Homo sapiens	121-124
23513691-8	2012	In addition, nitrogen addition decreased bacterial diversity, which is negatively related to soil total N content and positively related to soil NO3(-)-N heterogeneity.	Nitrogen	13-21	NBL1, DAN family BMP antagonist	Homo sapiens	145-148
22227893-0	2012	The Arabidopsis nitrate transporter NRT2.4 plays a double role in roots and shoots of nitrogen-starved plants.	Nitrogen	86-94	nitrate transporter 2:1	Arabidopsis thaliana	36-40
22227893-6	2012	In N-starved nrt2.4 mutants, nitrate uptake under low external supply and nitrate content in shoot phloem exudates was decreased.	Nitrogen	3-4	nitrate transporter 2:1	Arabidopsis thaliana	13-17
22033225-6	2012	RESULTS: A 6-10 times increase in the S/N ratio was observed with IRs as compared to LiPc deposits.	Nitrogen	40-41	lipase C, hepatic type	Rattus norvegicus	85-89
23251667-9	2012	The dominant negative GTPase variants resulting from cleavage of these 2A peptide constructs were found to be stable and active, and were successfully used to study the inhibitory effect on trafficking of the N-glycosylated CAH1 protein through the endomembrane system.	Nitrogen	209-210	alpha carbonic anhydrase 1	Arabidopsis thaliana	224-228
23155433-7	2012	miR826, a newly identified N-starvation-induced miRNA, was found to target the AOP2 gene.	Nitrogen	27-28	AOP2	Arabidopsis thaliana	79-83
22629371-8	2012	Zhonghuang-13) ATG8, GmATG8c, was selected from the 11 family members based on transcript analysis upon nitrogen deprivation.	Nitrogen	104-112	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	15-19
23056292-7	2012	The glycosylation studies showed the reduced N-linked sialylation of A2HSG in RA patients.	Nitrogen	45-46	alpha 2-HS glycoprotein	Homo sapiens	69-74
22880003-6	2012	Contrary to other NRT2 members, NRT2.6 expression was not induced by limiting but rather by high nitrogen levels, and no nitrate-related phenotype was found in the nrt2.6-1 mutant.	Nitrogen	97-105	nitrate transporter 2:1	Arabidopsis thaliana	32-36
23029040-1	2012	A 15-LOX, it is proposed, suppresses the growth of prostate cancer in part by converting arachidonic, eicosatrienoic, and/or eicosapentaenoic acids to n-6 hydroxy metabolites.	Nitrogen	62-63	arachidonate 15-lipoxygenase	Homo sapiens	2-8
22916108-1	2012	PRMT6 belongs to the family of Protein Arginine Methyltransferase (PRMT) enzymes that catalyze the methylation of guanidino nitrogens of arginine residues.	Nitrogen	124-133	protein arginine methyltransferase 6	Homo sapiens	0-5
22916115-8	2012	We showed that the inversion of DAL2 lower its own expression and reduces yeast fitness during nitrogen starvation.	Nitrogen	95-103	allantoicase	Saccharomyces cerevisiae S288C	32-36
22900004-7	2012	While invasion of U-NB1 cells was inhibited by blocking antibodies against CD57, neither invasion of SK-N-BE(2)-C cells nor adhesion of U-NB1 and SK-N-BE(2)-C cells was attenuated.	Nitrogen	19-21	beta-1,3-glucuronyltransferase 1	Homo sapiens	75-79
22761706-3	2012	Here we examine how the presence of intact riparian cover influences the impact of an invasive herbivorous snail, Tarebia granifera, on nitrogen (N) cycling in aquatic systems on the island of Trinidad.	Nitrogen	136-144	snail family transcriptional repressor 1	Homo sapiens	107-112
22761706-8	2012	Estimates of ecosystem N demand indicated that snail N excretion in fully closed, partially closed, and open canopy habitats supplied 2%, 11%, and 16% of integrated ecosystem N demand, respectively.	Nitrogen	23-24	snail family transcriptional repressor 1	Homo sapiens	47-52
22438913-9	2012	We next found that both IGF1R and IR were N-linked glyosylated in figitumumab-sensitive cells.	Nitrogen	42-43	insulin-like growth factor I receptor	Mus musculus	24-29
22479580-7	2012	We discovered that the transcription factor Gat1 (Are1) regulates the utilization of nitrogen differently between C. neoformans and C. gattii strains.	Nitrogen	85-93	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	Mus musculus	44-48
22427986-0	2012	Loss and recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions.	Nitrogen	59-60	cadherin 1	Homo sapiens	48-58
22438913-11	2012	We observed that an absence of N-linked glycosylation at N913 led to a lack of membranous localization of IGF1R and figitumumab insensitivity.	Nitrogen	31-32	insulin-like growth factor I receptor	Mus musculus	106-111
22438913-12	2012	CONCLUSION AND SIGNIFICANCE: The data suggest that the level of N-linked glycosylated IGF1R/IR heterodimeric receptor is highly associated with sensitivity to anti-IGF1R antibody in cancer cells.	Nitrogen	2-3	insulin-like growth factor I receptor	Mus musculus	86-117
22438913-12	2012	CONCLUSION AND SIGNIFICANCE: The data suggest that the level of N-linked glycosylated IGF1R/IR heterodimeric receptor is highly associated with sensitivity to anti-IGF1R antibody in cancer cells.	Nitrogen	2-3	insulin-like growth factor I receptor	Mus musculus	86-91
22389722-2	2012	Currently, it is unknown if these N-linked residues are required for hPAP protein stability and activity in vitro or in animal models of chronic pain.	Nitrogen	34-35	PDGFA associated protein 1	Homo sapiens	69-73
22039046-0	2011	Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine.	Nitrogen	0-8	solute carrier family 6 member 1	Homo sapiens	74-78
22412906-0	2012	Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization.	Nitrogen	63-64	gastric inhibitory polypeptide	Homo sapiens	14-17
22412906-7	2012	N-glycosylation enhances cell surface expression and function in parallel but exerts stronger control over the GIP receptor than the GLP-1 receptor.	Nitrogen	0-1	gastric inhibitory polypeptide	Homo sapiens	111-114
22412906-9	2012	N-glycosylation is also required for expression of the GIP receptor at the plasma membrane and efficient GIP potentiation of glucose-induced insulin secretion from the INS-1 pancreatic beta cell line.	Nitrogen	0-1	gastric inhibitory polypeptide	Rattus norvegicus	55-58
22412906-9	2012	N-glycosylation is also required for expression of the GIP receptor at the plasma membrane and efficient GIP potentiation of glucose-induced insulin secretion from the INS-1 pancreatic beta cell line.	Nitrogen	0-1	gastric inhibitory polypeptide	Rattus norvegicus	105-108
22412906-9	2012	N-glycosylation is also required for expression of the GIP receptor at the plasma membrane and efficient GIP potentiation of glucose-induced insulin secretion from the INS-1 pancreatic beta cell line.	Nitrogen	0-1	insulin	Homo sapiens	141-148
22412906-10	2012	Functional expression of a GIP receptor mutant lacking N-glycosylation is rescued by co-expressed wild type GLP1 receptor, which, together with data obtained using Bioluminescence Resonance Energy Transfer, suggests formation of a GIP-GLP1 receptor heteromer.	Nitrogen	55-56	gastric inhibitory polypeptide	Rattus norvegicus	27-30
22039046-1	2011	Nitrogen availability regulates the transcription of genes required to degrade non-preferentially utilized nitrogen sources by governing the localization and function of transcription activators, Gln3 and Gat1.	Nitrogen	0-8	solute carrier family 6 member 1	Homo sapiens	205-209
22039046-1	2011	Nitrogen availability regulates the transcription of genes required to degrade non-preferentially utilized nitrogen sources by governing the localization and function of transcription activators, Gln3 and Gat1.	Nitrogen	107-115	solute carrier family 6 member 1	Homo sapiens	205-209
21889485-3	2011	The lysozyme transferred to the gaseous nitrogen phase after 5 min of bubbling with no exogenous detergent.	Nitrogen	40-48	lysozyme	Homo sapiens	4-12
21978530-5	2011	This is supported by the results that have shown that co-treatment with antioxidants, VC, L-GSH and MitoQ(10), decreased 2-ME-induced generation of ROS and the loss of the mitochondrial membrane potential, increased the Bcl-2/Bax ratio, decreased 2-ME-induced activation of caspase-9 and caspase-3 and the up-regulation of apoptosis-inducing factor (AIF), and prevented 2-ME-induced apoptosis in SK-N-SH and SH-SY5Y cells.	Nitrogen	399-400	BCL2 apoptosis regulator	Homo sapiens	220-225
22107254-2	2011	Subsequent addition of Li(2,5-Me(2)C(4)H(2)N) to 4 yielded yellow W(O)(CH-t-Bu)(OHMT)(Me(2)Pyr)(PMe(2)Ph) (5).	Nitrogen	43-44	solute carrier family 5 member 7	Homo sapiens	71-75
22180204-5	2011	Furthermore, we applied the proposed method for the analyses of N-linked sialo- and asialo-oligosaccharides in glycoproteins (ribonuclease B, fetuin, and recombinant human erythropoietin).	Nitrogen	64-65	erythropoietin	Homo sapiens	172-186
21908519-0	2011	Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.	Nitrogen	96-97	beta-1,3-glucuronyltransferase 1	Homo sapiens	17-23
21908519-0	2011	Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.	Nitrogen	96-97	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	36-41
21986896-2	2011	Compound 1 is a polymer in which ligand L coordinates to tetrahedral Co(II) ions in a bidentate bridging fashion using the pyridine nitrogen and carbonyl oxygen atoms.	Nitrogen	132-140	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	69-75
21900457-7	2011	Expressing FXYD5 in M1 cells resulted in a decrease in N-glycosylation of beta1 Na(+)-K(+)-ATPase, while silencing it in H1299 cells had an opposite effect.	Nitrogen	55-56	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	74-79
21999508-3	2011	We now disclose the finding that new analogues of 1 with an N-linked cyclic amide moiety attached to the ethyl bridge, such as 24m, retain the broad-spectrum antibacterial activity of 1 but show significantly less hERG inhibition (IC(50)= 31 muM for 24m) and higher free fraction than 1.	Nitrogen	60-61	ETS transcription factor ERG	Homo sapiens	214-218
21926297-5	2011	Specifically, a serine/threonine PAS-kinase, Rim15p, that is known to integrate phosphate, nitrogen, and carbon sensing, can also control Mn antioxidant activity in yeast.	Nitrogen	91-99	protein kinase RIM15	Saccharomyces cerevisiae S288C	45-51
21926297-6	2011	Rim15p is negatively regulated by the phosphate-sensing kinase complex Pho80p/Pho85p and by the nitrogen-sensing Akt/S6 kinase homolog, Sch9p.	Nitrogen	96-104	protein kinase RIM15	Saccharomyces cerevisiae S288C	0-6
21926297-6	2011	Rim15p is negatively regulated by the phosphate-sensing kinase complex Pho80p/Pho85p and by the nitrogen-sensing Akt/S6 kinase homolog, Sch9p.	Nitrogen	96-104	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	136-141
22033294-0	2011	Commentary: the history and place of n-of-1 trials: a commentary on Hogben and Sim.	Nitrogen	5-6	SIM bHLH transcription factor 2	Homo sapiens	79-82
21983680-1	2011	Two rhenium(I) carbonyl complexes of the type fac-[Re(CO)(3)(N^C)X] where N^C is an N-heterocyclic carbene [3-butyl-1-(2"-pyridyl)benzimidazolin-2-ylidene] and X is either Cl or Br have been synthesised via an in situ method from [Re(CO)(5)X] and a respective benzimidazolium salt.	Nitrogen	61-63	FA complementation group C	Homo sapiens	46-49
21421995-4	2011	MALDI-TOF analysis of total N-linked glycoconjugates indicated a decrease in the relative amount of sialylated glycans in both COG3 KD and COG4 KD cells.	Nitrogen	28-29	component of oligomeric golgi complex 3	Homo sapiens	127-131
22122843-5	2011	The electrical transport properties of the device were studied in the range of 80 to 450 K. The faster rise and decay time indicate that the InN NRs/n-Si heterojunction is highly sensitive to IR light.	Nitrogen	18-19	growth hormone releasing hormone	Homo sapiens	141-144
21303349-2	2011	Similarly reactive oxygen/nitrogen species (ROS/RNS) produced during normal metabolic activities, specifically oxidative phosphorylation of the cell, are scavenged by antioxidant enzymes like superoxide dismutase (SOD), catalase but impaired metabolic pathways tend to generate elevated levels of these ROS/RNS.	Nitrogen	26-34	superoxide dismutase 1	Homo sapiens	192-212
22649382-8	2011	N-glycosylation receptor mutants are not misfolded as, once localized on the cell surface in overexpression conditions, they can bind and respond to Tpo.	Nitrogen	0-1	thrombopoietin	Homo sapiens	149-152
22649382-9	2011	Our data indicate that extracellular domain N-glycosylation sites regulate in a combinatorial manner cell surface localization of TpoR.	Nitrogen	44-45	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	130-134
22649382-10	2011	We discuss how mutations around TpoR N-glycosylation sites might contribute to inefficient receptor traffic and disease.	Nitrogen	37-38	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	32-36
22008282-10	2011	AFM micrograph and N(2) isotherms confirm that the presence of vanillin modify the physical structure of PSf/Vanillin microcapsules as it is trapped in the capsule porosity.	Nitrogen	19-23	insulin like growth factor binding protein 7	Homo sapiens	105-108
22649382-0	2011	Extracellular domain N-glycosylation controls human thrombopoietin receptor cell surface levels.	Nitrogen	21-22	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	52-75
22649382-3	2011	Single N-glycosylation mutants at any of the four sites were able to acquire the mature N-glycosylated pattern, but exhibited a decreased Tpo-dependent JAK2-STAT response in stably transduced Ba/F3 or Ba/F3-JAK2 cell lines.	Nitrogen	7-8	thrombopoietin	Homo sapiens	138-141
22649382-4	2011	The ability of JAK2 to promote cell surface localization and stability of TpoR required the first N-glycosylation site (Asn117).	Nitrogen	98-99	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	74-78
22649382-6	2011	TpoR mutants lacking three N-glycosylation sites were defective in maturation, but N-glycosylation on the single remaining site could be detected by sensitivity to PNGaseF.	Nitrogen	27-28	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	0-4
22649382-7	2011	The TpoR mutant defective in all four N-glycosylation sites was severely impaired in plasma membrane localization and was degraded by the proteasome.	Nitrogen	38-39	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	4-8
21911496-10	2011	Taken together we propose a novel anti-inflammatory mechanism of endothelial PPARgamma activation that involves targeting protein post-translational modification of adhesion molecules, specifically N-glycosylation.	Nitrogen	198-199	peroxisome proliferator activated receptor gamma	Homo sapiens	77-86
22219826-1	2011	In the title compound, [Co(C(6)H(4)NO(2))(3)], the Co(III) ion lies on a threefold rotation axis and is in a distorted octa-hedral environment defined by three N and three O donor atoms from three fac-disposed pyridine-2-carboxyl-ate ligands.	Nitrogen	35-36	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	51-58
21303349-2	2011	Similarly reactive oxygen/nitrogen species (ROS/RNS) produced during normal metabolic activities, specifically oxidative phosphorylation of the cell, are scavenged by antioxidant enzymes like superoxide dismutase (SOD), catalase but impaired metabolic pathways tend to generate elevated levels of these ROS/RNS.	Nitrogen	26-34	superoxide dismutase 1	Homo sapiens	214-217
21303349-2	2011	Similarly reactive oxygen/nitrogen species (ROS/RNS) produced during normal metabolic activities, specifically oxidative phosphorylation of the cell, are scavenged by antioxidant enzymes like superoxide dismutase (SOD), catalase but impaired metabolic pathways tend to generate elevated levels of these ROS/RNS.	Nitrogen	26-34	catalase	Homo sapiens	220-228
21481194-8	2011	RESULTS: We demonstrate that Ror1 is extensively modified by N-linked glycosylation.	Nitrogen	61-62	receptor tyrosine kinase like orphan receptor 1	Homo sapiens	29-33
22023129-7	2011	For all 3 species, inhibitors of CYP3A4, CYP2A6, CYP2C19, CYP2B6, and CYP2C9 diminished N-demethylation of ketamine.	Nitrogen	88-89	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	33-39
21720965-7	2011	Under the optimal conditions, the as-prepared biosensor exhibited a good response performance to glucose with a linear range from 6 muM to 1.2 mM with a detection limit of 0.1 muM glucose (S/N = 3).	Nitrogen	191-192	latexin	Homo sapiens	132-135
21803416-2	2011	The present study describes the preparation of 3D micronized (300-600 mum) amniotic membrane (mAM) by means of repeated freeze-thawing cycles to deplete cell components and homogenized with a macrohomogenizer in liquid nitrogen.	Nitrogen	219-227	PZP, alpha-2-macroglobulin like	Mus musculus	94-97
21958523-4	2011	The average chemical oxygen demand (COD) removal efficiency was 79.8-86.8% in the AF and the average total nitrogen removal efficiency was 50.5-80.8% in the AF/BAF system.	Nitrogen	107-115	BAF nuclear assembly factor 1	Homo sapiens	160-163
21720965-7	2011	Under the optimal conditions, the as-prepared biosensor exhibited a good response performance to glucose with a linear range from 6 muM to 1.2 mM with a detection limit of 0.1 muM glucose (S/N = 3).	Nitrogen	191-192	latexin	Homo sapiens	176-179
22242479-4	2011	The experiment results showed that the emission peaks of N2 (C3 pi(u)) reached the maximum at the nitrogen flow rate of 80 mL x min(-1) with increasing addition of nitrogen, the gas temperature increased from 342 to 523 K when the input power increased from 30 to 210 W, and the vibrational temperature changed slightly when the gas flow rate of nitrogen increased from 30 to 140 mL x min(-1).	Nitrogen	98-106	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
21999734-1	2011	This study describes the interaction between human acetylcholinesterase (AChE), a key regulator of central and peripheral cholinergic function, and the widely used nitrogen mustard alkylating agent, cyclophosphamide (CP).	Nitrogen	164-172	acetylcholinesterase (Cartwright blood group)	Homo sapiens	51-71
21999734-1	2011	This study describes the interaction between human acetylcholinesterase (AChE), a key regulator of central and peripheral cholinergic function, and the widely used nitrogen mustard alkylating agent, cyclophosphamide (CP).	Nitrogen	164-172	acetylcholinesterase (Cartwright blood group)	Homo sapiens	73-77
22242479-4	2011	The experiment results showed that the emission peaks of N2 (C3 pi(u)) reached the maximum at the nitrogen flow rate of 80 mL x min(-1) with increasing addition of nitrogen, the gas temperature increased from 342 to 523 K when the input power increased from 30 to 210 W, and the vibrational temperature changed slightly when the gas flow rate of nitrogen increased from 30 to 140 mL x min(-1).	Nitrogen	164-172	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
22242479-4	2011	The experiment results showed that the emission peaks of N2 (C3 pi(u)) reached the maximum at the nitrogen flow rate of 80 mL x min(-1) with increasing addition of nitrogen, the gas temperature increased from 342 to 523 K when the input power increased from 30 to 210 W, and the vibrational temperature changed slightly when the gas flow rate of nitrogen increased from 30 to 140 mL x min(-1).	Nitrogen	164-172	CD59 molecule (CD59 blood group)	Homo sapiens	128-134
21816953-9	2011	DTIC N-demethylation by the E161K, E256K, and I458V mutants exhibited Michaelis-Menten kinetics, with decreases in K(m) (183-249 muM) that doubled the catalytic efficiency (p &lt; 0.05) relative to wild-type CYP1A1 (K(m), 408 +- 43 muM; V(max), 28 +- 4 pmol   min(-1)   pmol of P450(-1)).	Nitrogen	5-6	latexin	Homo sapiens	129-132
22256424-3	2011	Several mutants of murine AE1 tagged with an N-terminal enhanced green fluorescent protein (EGFP) and/or an extracellular FLAG epitope inserted adjacent to the N-glycosylation site were prepared, and their expression was analyzed in HEK293 or COS-1 cells by immunofluorescence microscopy, biotinylation, and deglycosylation.	Nitrogen	45-46	solute carrier family 4 (anion exchanger), member 1	Mus musculus	26-29
21928852-0	2011	Intermolecular oxidative C-N bond formation under metal-free conditions: control of chemoselectivity between aryl sp2 and benzylic sp3 C-H bond imidation.	Nitrogen	27-28	Sp2 transcription factor	Homo sapiens	114-117
21816953-9	2011	DTIC N-demethylation by the E161K, E256K, and I458V mutants exhibited Michaelis-Menten kinetics, with decreases in K(m) (183-249 muM) that doubled the catalytic efficiency (p &lt; 0.05) relative to wild-type CYP1A1 (K(m), 408 +- 43 muM; V(max), 28 +- 4 pmol   min(-1)   pmol of P450(-1)).	Nitrogen	5-6	latexin	Homo sapiens	232-235
22102807-3	2011	Activation of the P2X7 receptor opens a cation-specific channel that alters the ionic environment of the cell, activating several pathways, including (i) the inflammasome, leading to production of IL-1beta and IL-18; (ii) the stress-activated protein kinase pathway, resulting in apoptosis; (iii) the mitogen-activated protein kinase pathway, leading to generation of reactive oxygen and nitrogen intermediates; and (iv) phospholipase D, stimulating phagosome-lysosome fusion.	Nitrogen	388-396	purinergic receptor P2X 7	Homo sapiens	18-31
21866283-1	2011	The monoanionic N(4)O ligand N-methyl-N,N"-bis(2-pyridylmethyl)ethylenediamine-N"-acetate (mebpena(-)) undergoes oxidative C-N bond cleavage in the presence of Co(II) and O(2).	Nitrogen	16-17	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	160-166
21880708-3	2011	Here, we investigated insulin analogues with selective N-methylations of peptide bond amides at positions B24, B25, or B26 to delineate their structural and functional contribution to the dimer interface.	Nitrogen	55-56	insulin	Homo sapiens	22-29
21880708-7	2011	Interestingly, although the N-methylation in [NMeTyrB26]-insulin or [NMePheB24]-insulin resulted in K(d) values of 142 and 587 muM, respectively, the [NMePheB25]-insulin did not form dimers even at high concentrations.	Nitrogen	28-29	insulin	Homo sapiens	57-64
21880708-7	2011	Interestingly, although the N-methylation in [NMeTyrB26]-insulin or [NMePheB24]-insulin resulted in K(d) values of 142 and 587 muM, respectively, the [NMePheB25]-insulin did not form dimers even at high concentrations.	Nitrogen	28-29	insulin	Homo sapiens	80-87
21880708-7	2011	Interestingly, although the N-methylation in [NMeTyrB26]-insulin or [NMePheB24]-insulin resulted in K(d) values of 142 and 587 muM, respectively, the [NMePheB25]-insulin did not form dimers even at high concentrations.	Nitrogen	28-29	latexin	Homo sapiens	127-130
21880708-7	2011	Interestingly, although the N-methylation in [NMeTyrB26]-insulin or [NMePheB24]-insulin resulted in K(d) values of 142 and 587 muM, respectively, the [NMePheB25]-insulin did not form dimers even at high concentrations.	Nitrogen	28-29	insulin	Homo sapiens	80-87
21928852-0	2011	Intermolecular oxidative C-N bond formation under metal-free conditions: control of chemoselectivity between aryl sp2 and benzylic sp3 C-H bond imidation.	Nitrogen	27-28	Sp3 transcription factor	Homo sapiens	131-134
21890358-3	2011	Molecular modeling studies for 9f showed that the SO(2)NH(2) group assumes a position within the secondary pocket of the COX-2 active site wherein the SO(2)NH(2) oxygen atom is hydrogen bonded to the H90 residue (2.90A), the SO(2)NH(2) nitrogen atom forms a hydrogen bond with L352 (N O=2.80A), and the acetyl group is positioned in the vicinity of the S530 residue where the acetyl oxygen atom undergoes hydrogen bonding to L531 (2.99A).	Nitrogen	236-244	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	121-126
21907028-5	2011	The total nitrogen system featured a limit of detection of 0.05 mg N L(-1), 1%RSD (1 mg N L(-1) as ammonium chloride, n=10), a coefficient of determination of 0.9989 over the calibration range 0.0-2.0 mg N L(-1), and a throughput of 5 sample h(-1) measured in triplicate.	Nitrogen	10-18	nuclear receptor subfamily 4 group A member 1	Homo sapiens	118-122
21898612-5	2011	While, in ion-molecule reactions of PtCH(+) with C(2) hydrocarbons, the relative rates decrease with increasing n, the opposite trend holds true for Pt(2)CH(+).	Nitrogen	8-9	patched 1	Homo sapiens	36-40
21820242-0	2011	Non-isothermal decomposition kinetics, heat capacity and thermal safety of 37.2/44/16/2.2/0.2/0.4-GAP/CL-20/Al/N-100/PCA/auxiliaries mixture.	Nitrogen	0-1	epithelial membrane protein 1	Homo sapiens	102-107
21913670-2	2011	The Co(II) complexes generally adopt a tetrahedral configuration of general formula [(NP2)Co(I)(2)], wherein the two phosphorus donors are bound to the metal center but the central N-donor remains unbound.	Nitrogen	86-87	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
21852240-6	2011	The identification of an enzyme that integrates some of the features of OST in a cytoplasmic pathway defines a novel class of N-linked protein glycosylation found in pathogenic bacteria.	Nitrogen	126-127	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	72-75
21983822-1	2011	Enantioselective CE with sulfated cyclodextrins as chiral selectors was used to determine the CYP3A4-catalyzed N-demethylation kinetics of ketamine to norketamine and its inhibition in the presence of ketoconazole in vitro.	Nitrogen	111-112	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	94-100
21990137-4	2011	We observed that although PrP mutation at either residue 183 from Thr to Ala (PrPT183A) or at residue 198 from Phe to Ser (PrPF198S) affects glycosylation at both N-linked glycosylation sites, the T183A mutation that results in intracellular retention significantly increased the formation of iPrPC.	Nitrogen	163-164	prion protein	Homo sapiens	26-29
21934004-6	2011	Dietary supplementation with 100 mg/kg of CNP-Cu increased (P &lt; 0.05) concentrations of serum total protein and albumin, and decreased (P &lt; 0.05) the content of urea nitrogen in serum.	Nitrogen	172-180	2',3'-cyclic nucleotide 3' phosphodiesterase	Homo sapiens	42-45
21852023-3	2011	The unsubstituted N-benzyl derivative (8a) showed the inhibition of c-Src kinase with GI(50) values of 1.34 muM and 2.30 muM in NIH3T3/c-Src527F and SYF/c-Src527F cells, respectively.	Nitrogen	18-19	c-src tyrosine kinase	Mus musculus	68-80
21793950-7	2011	The activation of IL-1R/TLR signalling mediates rapid post-translational changes in N-methyl-d-aspartate-gated ion channels in neurons.	Nitrogen	84-85	interleukin 1 receptor type 1	Homo sapiens	18-23
21258830-5	2011	QTAIM identified the weak H-bonds formed between the methyl hydrogen of DMSO and the N atom in NA in some complexes (AB5, AB6 and AB7), which cannot be further confirmed by NBO and other methods, so there are probably no interactions between hydrogen and nitrogen atoms among these complexes.	Nitrogen	85-86	NBPF member 10	Homo sapiens	122-125
21889444-0	2011	Biomimetic N-terminal alkylation of peptoid analogues of surfactant protein C.	Nitrogen	11-12	surfactant protein C	Homo sapiens	57-77
21795704-4	2011	Here, several lines of evidence indicate that the N-linked glycosylation of AChE(T) plays a major role for acquisition of AChE full enzymatic activity but does not affect its oligomerization.	Nitrogen	50-51	acetylcholinesterase (Cartwright blood group)	Homo sapiens	76-80
21795704-4	2011	Here, several lines of evidence indicate that the N-linked glycosylation of AChE(T) plays a major role for acquisition of AChE full enzymatic activity but does not affect its oligomerization.	Nitrogen	50-51	acetylcholinesterase (Cartwright blood group)	Homo sapiens	122-126
21795704-5	2011	The expression of the AChE(T) mutant, in which all N-glycosylation sites were deleted, together with PRiMA in HEK293T cells produced a glycan-depleted PRiMA-linked AChE tetramer but with a much higher K(m) value as compared with the wild type.	Nitrogen	51-52	acetylcholinesterase (Cartwright blood group)	Homo sapiens	22-26
21795704-5	2011	The expression of the AChE(T) mutant, in which all N-glycosylation sites were deleted, together with PRiMA in HEK293T cells produced a glycan-depleted PRiMA-linked AChE tetramer but with a much higher K(m) value as compared with the wild type.	Nitrogen	51-52	acetylcholinesterase (Cartwright blood group)	Homo sapiens	164-168
21771787-0	2011	Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate.	Nitrogen	117-118	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Mus musculus	27-57
21771787-0	2011	Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate.	Nitrogen	117-118	beta-1,3-glucuronyltransferase 1	Homo sapiens	150-155
21783359-2	2011	Compounds containing phenyl or aromatic nitrogen heterocycle substituents inhibited both types of signalling with HEK-293T cells in culture, with a selectivity preference for TGF-beta1.	Nitrogen	40-48	transforming growth factor beta 1	Homo sapiens	175-184
22082268-0	2011	Influence of placental mannose/n-acetyl glucosamine-binding proteins on the interaction of insulin and insulin-like growth factors with their receptors.	Nitrogen	1-2	insulin	Homo sapiens	91-98
21770429-5	2011	We also rationally designed mutations at and around the N-glycosylation sites based on sequence alignment with mouse IL5Ralpha and other cytokine receptors.	Nitrogen	56-57	interleukin 5 receptor, alpha	Mus musculus	117-126
21645885-0	2011	1-Deoxy-D-galactonojirimycins with dansyl capped N-substituents as beta-galactosidase inhibitors and potential probes for GM1 gangliosidosis affected cell lines.	Nitrogen	49-50	beta galactosidase	Drosophila melanogaster	67-85
22082268-0	2011	Influence of placental mannose/n-acetyl glucosamine-binding proteins on the interaction of insulin and insulin-like growth factors with their receptors.	Nitrogen	1-2	insulin	Homo sapiens	103-110
21491887-5	2011	We use nonlabeled and residue-specifically (15)N-labeled Abeta(1-16).	Nitrogen	47-48	amyloid beta precursor protein	Homo sapiens	57-62
21791552-6	2011	Regression analysis revealed that CD34+, CD34+/KDR+ and CD34+/CD45- hematopoietic CPCs were associated positively with eGFR and negatively with blood urea nitrogen and serum creatinine.	Nitrogen	155-163	CD34 molecule	Homo sapiens	34-38
21791552-6	2011	Regression analysis revealed that CD34+, CD34+/KDR+ and CD34+/CD45- hematopoietic CPCs were associated positively with eGFR and negatively with blood urea nitrogen and serum creatinine.	Nitrogen	155-163	CD34 molecule	Homo sapiens	41-45
21791552-6	2011	Regression analysis revealed that CD34+, CD34+/KDR+ and CD34+/CD45- hematopoietic CPCs were associated positively with eGFR and negatively with blood urea nitrogen and serum creatinine.	Nitrogen	155-163	CD34 molecule	Homo sapiens	41-45
21637915-5	2011	Only the second peptide (emp#2), which contains a putative N-glycosylation site sequence, inhibited emmprin-stimulated production of MMP-2 in co-cultures of fibroblasts and several different human tumor cells types, including carcinoma, sarcoma, melanoma, leukemia and glioma cells.	Nitrogen	59-60	epithelial membrane protein 2	Homo sapiens	25-30
21816515-9	2011	Molecular docking studies using a homology model of the 5-HT(1A) receptor revealed a significant role of the N-8 atom of the tropane core in stabilising the ligand-receptor complex due to strong hydrogen bonding with Asp116 located in the TMH 3 helix.	Nitrogen	109-110	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	56-73
21775536-6	2011	Extensive amino acid substitutions in the GP5 sequence translated from ORF5 were found, particularly in the potential neutralization epitope and the N-glycosylation sites.	Nitrogen	149-150	glycoprotein V platelet	Homo sapiens	42-45
21761893-2	2011	The stepwise union of complex amines in the form of mixed diazenes followed by photoexpulsion of dinitrogen in a solvent cage provides completely guided assembly at challenging C(sp(3))-C(sp(3)) and C(sp(3))-C(sp(2)) connections.	Nitrogen	97-107	regulator of calcineurin 2	Homo sapiens	208-215
21621574-9	2011	The protein interaction of BCATm and GDH1 promotes regeneration of PLP-BCATm which then binds to BCKDC resulting in channeling of the BCKA products from BCATm first half reaction to E1 and promoting BCAA oxidation and net nitrogen transfer from BCAAs.	Nitrogen	222-230	branched chain amino acid transaminase 2	Homo sapiens	27-32
21621574-9	2011	The protein interaction of BCATm and GDH1 promotes regeneration of PLP-BCATm which then binds to BCKDC resulting in channeling of the BCKA products from BCATm first half reaction to E1 and promoting BCAA oxidation and net nitrogen transfer from BCAAs.	Nitrogen	222-230	branched chain amino acid transaminase 2	Homo sapiens	71-76
21621574-9	2011	The protein interaction of BCATm and GDH1 promotes regeneration of PLP-BCATm which then binds to BCKDC resulting in channeling of the BCKA products from BCATm first half reaction to E1 and promoting BCAA oxidation and net nitrogen transfer from BCAAs.	Nitrogen	222-230	branched chain amino acid transaminase 2	Homo sapiens	71-76
21621574-10	2011	The cycling of nitrogen through glutamate via the actions of BCATm and GDH1 releases free ammonia.	Nitrogen	15-23	branched chain amino acid transaminase 2	Homo sapiens	61-66
21623972-7	2011	HY5 is also important for the coordination of nitrogen and sulfur assimilation, as, unlike the wild-type, hy5 mutants do not undergo a reduction in sulfate uptake and APR activity during nitrogen starvation.	Nitrogen	46-54	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	0-3
21623972-7	2011	HY5 is also important for the coordination of nitrogen and sulfur assimilation, as, unlike the wild-type, hy5 mutants do not undergo a reduction in sulfate uptake and APR activity during nitrogen starvation.	Nitrogen	187-195	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	0-3
21547922-6	2011	Finally, the application of NO(3) (-) to plants was detected when it was combined with high levels of organic N sources, from 99:1 organic:inorganic N ratio.	Nitrogen	110-111	NBL1, DAN family BMP antagonist	Homo sapiens	28-37
21750220-7	2011	In vitro activity of PSMA ADC was also dependent on internalization and proper N-glycosylation/folding of PSMA.	Nitrogen	79-80	folate hydrolase 1	Homo sapiens	21-25
21750220-7	2011	In vitro activity of PSMA ADC was also dependent on internalization and proper N-glycosylation/folding of PSMA.	Nitrogen	79-80	folate hydrolase 1	Homo sapiens	106-110
21671454-3	2011	The nitrogen atoms of 2 are unequivocally determined by the X-ray crystal analysis of a single crystal of rac-2 whereas the nitrogen atoms cannot be assigned at all in the case of rac-1.	Nitrogen	4-12	Rac family small GTPase 2	Homo sapiens	106-111
21600194-0	2011	The effects of nitrogen-heme-iron coordination on substrate affinities for cytochrome P450 2E1.	Nitrogen	15-23	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	75-94
21788519-2	2011	We previously isolated the Arabidopsis high nitrogen-insensitive 9-1 (hni9-1) mutant, impaired in the systemic feedback repression of the root nitrate transporter NRT2.1 by high N supply.	Nitrogen	44-52	nitrate transporter 2:1	Arabidopsis thaliana	163-167
21788519-4	2011	HNI9/AtIWS1 acts in roots to repress NRT2.1 transcription in response to high N supply.	Nitrogen	1-2	nitrate transporter 2:1	Arabidopsis thaliana	37-41
21772271-5	2011	Decreased nitrate reductase activity in siz1-2 plants resulted in low nitrogen concentrations, low nitric oxide production and high nitrate content in comparison with wild-type plants.	Nitrogen	70-78	nitrate reductase 1	Arabidopsis thaliana	10-27
21857803-3	2011	Nitrogen is also leached from agricultural lands as the water-soluble form NO3-, which increases nutrient overload in rivers, lakes, and oceans, causing "dead zones", reducing property values and the diversity of aquatic life, and damaging our drinking water and aquatic-associated industries such as fishing and tourism.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	75-78
22097361-2	2011	During the experiment period, nitrogen deposition increased the soil NH4+ -N, NO3- -N, and available N contents, as compared with the control, but the increments differed with stand types, soil layers, nitrogen treatment types, and treatment duration.	Nitrogen	30-38	NBL1, DAN family BMP antagonist	Homo sapiens	78-81
21558494-1	2011	Human corticosteroid-binding globulin (CBG), a heavily glycosylated protein containing six N-linked glycosylation sites, transports cortisol and other corticosteroids in blood circulation.	Nitrogen	91-92	serpin family A member 6	Homo sapiens	6-37
21558494-1	2011	Human corticosteroid-binding globulin (CBG), a heavily glycosylated protein containing six N-linked glycosylation sites, transports cortisol and other corticosteroids in blood circulation.	Nitrogen	91-92	serpin family A member 6	Homo sapiens	39-42
21558494-2	2011	Here, we investigate the biological importance of the N-glycans of CBG derived from human serum by performing a structural and functional characterization of CBG N-glycosylation.	Nitrogen	54-55	serpin family A member 6	Homo sapiens	67-70
22097361-4	2011	Ammonium nitrogen deposition had larger effects on soil NH4+ -N content, nitrate nitrogen deposition had larger effects on soil NO3- -N content, while mixed ammonium and nitrate nitrogen deposition increased the contents of both soil NH4+ -N and soil NO3- -N, and the increments were higher than those of ammonium nitrogen deposition and nitrate nitrogen deposition, suggesting the additive effects of the mixed ammonium and nitrate nitrogen deposition on the forest soil available N.	Nitrogen	81-89	NBL1, DAN family BMP antagonist	Homo sapiens	128-131
21632540-3	2011	EDEM1 has five N-linked glycosylation sites with the most C-terminal site recognized poorly cotranslationally, resulting in the accumulation of EDEM1 containing four or five glycans.	Nitrogen	15-16	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	0-5
21632540-3	2011	EDEM1 has five N-linked glycosylation sites with the most C-terminal site recognized poorly cotranslationally, resulting in the accumulation of EDEM1 containing four or five glycans.	Nitrogen	15-16	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	144-149
21653836-6	2011	Furthermore, the population size of N-myristoylated Nef peptide-specific T cells was found to increase significantly in the circulation of SIV-infected monkeys.	Nitrogen	36-37	S100 calcium binding protein B	Homo sapiens	52-55
21653836-5	2011	A rhesus macaque CD8(+) T cell line was established that specifically recognized N-myristoylated, but not unmodified, peptides of the Nef protein.	Nitrogen	81-82	S100 calcium binding protein B	Homo sapiens	134-137
21653836-0	2011	Cutting edge: T cells monitor N-myristoylation of the Nef protein in simian immunodeficiency virus-infected monkeys.	Nitrogen	30-31	nef protein	Simian immunodeficiency virus	54-57
21653836-3	2011	This biochemical reaction, referred to as N-myristoylation, assists its targeting to the plasma membrane, thereby supporting the immunosuppressive activity proposed for the Nef protein.	Nitrogen	42-43	S100 calcium binding protein B	Homo sapiens	173-176
21653836-4	2011	In this study, we show that the host immunity is equipped with CTLs capable of sensing N-myristoylation of the Nef protein.	Nitrogen	87-88	S100 calcium binding protein B	Homo sapiens	111-114
21922802-6	2011	The concentrations of NH4+ and NO3- were found to increase and contributed to the high nitrogen amount in precipitation.	Nitrogen	87-95	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
21515415-6	2011	The effect of site-specific N-glycosylation removal on PLTP secretion varied from a modest enhancement (15% and 60%), or essentially no effect, to a reduction in secretion (8%, 14% and 32%).	Nitrogen	28-29	phospholipid transfer protein	Cricetulus griseus	55-59
21515415-7	2011	Removal of N-glycosylation at any one of the six glycosylation sites resulted in a significant 35-78% decrease in PLTP activity, and a significant 29-80% decrease in PLTP specific activity compared to wild type.	Nitrogen	11-12	phospholipid transfer protein	Cricetulus griseus	114-118
21515415-7	2011	Removal of N-glycosylation at any one of the six glycosylation sites resulted in a significant 35-78% decrease in PLTP activity, and a significant 29-80% decrease in PLTP specific activity compared to wild type.	Nitrogen	11-12	phospholipid transfer protein	Cricetulus griseus	166-170
20927523-0	2011	Inhibition of N-linked glycosylation by tunicamycin induces E-cadherin-mediated cell-cell adhesion and inhibits cell proliferation in undifferentiated human colon cancer cells.	Nitrogen	14-15	cadherin 1	Homo sapiens	60-70
21586563-6	2011	Using progesterone as substrate for bacterially expressed purified human P450c17, the Michaelis constant for 17alpha-hydroxylase activity supported by N-27 POR or N-27 POR-G3H6 were 1.73 or 1.49 mum, and the maximal velocity was 0.029 or 0.026 pmol steroids per picomole P450 per minute, respectively.	Nitrogen	151-152	cytochrome p450 oxidoreductase	Homo sapiens	156-159
21586563-6	2011	Using progesterone as substrate for bacterially expressed purified human P450c17, the Michaelis constant for 17alpha-hydroxylase activity supported by N-27 POR or N-27 POR-G3H6 were 1.73 or 1.49 mum, and the maximal velocity was 0.029 or 0.026 pmol steroids per picomole P450 per minute, respectively.	Nitrogen	163-164	cytochrome p450 oxidoreductase	Homo sapiens	168-171
21586563-7	2011	Using 17-hydroxypregnenolone as the P450c17 substrate, the Michaelis constant for 17,20 lyase activity using N-27 POR or N-27 POR-G3H6 was 1.92 or 1.89 mum and the maximal velocity was 0.041 or 0.042 pmol steroid per picomole P450 per minute, respectively.	Nitrogen	109-110	cytochrome p450 oxidoreductase	Homo sapiens	114-117
21586563-7	2011	Using 17-hydroxypregnenolone as the P450c17 substrate, the Michaelis constant for 17,20 lyase activity using N-27 POR or N-27 POR-G3H6 was 1.92 or 1.89 mum and the maximal velocity was 0.041 or 0.042 pmol steroid per picomole P450 per minute, respectively.	Nitrogen	109-110	cytochrome p450 oxidoreductase	Homo sapiens	126-129
21586563-7	2011	Using 17-hydroxypregnenolone as the P450c17 substrate, the Michaelis constant for 17,20 lyase activity using N-27 POR or N-27 POR-G3H6 was 1.92 or 1.89 mum and the maximal velocity was 0.041 or 0.042 pmol steroid per picomole P450 per minute, respectively.	Nitrogen	121-122	cytochrome p450 oxidoreductase	Homo sapiens	114-117
21586563-7	2011	Using 17-hydroxypregnenolone as the P450c17 substrate, the Michaelis constant for 17,20 lyase activity using N-27 POR or N-27 POR-G3H6 was 1.92 or 1.89 mum and the maximal velocity was 0.041 or 0.042 pmol steroid per picomole P450 per minute, respectively.	Nitrogen	121-122	cytochrome p450 oxidoreductase	Homo sapiens	126-129
21586563-8	2011	Thus, N-27 POR-G3H6 is equally active as native N-27 POR.	Nitrogen	6-7	cytochrome p450 oxidoreductase	Homo sapiens	11-14
21836943-1	2011	In the title complex, [Co(C(10)H(6)O(2))(C(18)H(18)N(4))]PF(6) 0.5H(2)O, the Co(III) ion is six-coordinated in a distorted octa-hedral geometry by four N atoms from a tris-(2-pyridyl-meth-yl)amine ligand and two O atoms from a naphthalene-2,3-diolate ligand.	Nitrogen	51-52	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	77-84
21591763-5	2011	The N-glycosylated peptides of zebrafish were then captured by the solid-phase extraction of N-linked glycopeptides (SPEG) method and the peptides were identified with an LTQ OrbiTrap Velos mass spectrometer.	Nitrogen	4-5	striated muscle enriched protein kinase a	Danio rerio	117-121
21600204-0	2011	Essential residues in the H-NS binding site of Hha, a co-regulator of horizontally acquired genes in Enterobacteria.	Nitrogen	28-30	anosmin 1	Homo sapiens	47-50
21600945-7	2011	TPM-increased B1R mRNA was prevented by co-treatments with N-acetyl-l-cysteine (potent antioxidant), diphenyleneiodonium (NADPH oxidase inhibitor), IL-1Ra (interleukin-1R antagonist) and SN-50 (specific inhibitor of NF-kB activation) but not by pentoxifylline (TNF-alpha release inhibitor), indomethacin and niflumic acid (COX-1 and -2 inhibitors).	Nitrogen	20-21	bradykinin receptor B1	Homo sapiens	14-17
21550978-0	2011	N-linked glycosylation regulates human proteinase-activated receptor-1 cell surface expression and disarming via neutrophil proteinases and thermolysin.	Nitrogen	0-1	coagulation factor II thrombin receptor	Homo sapiens	39-70
21550978-4	2011	We have analyzed the role of N-linked glycosylation in regulating proteinase activation/disarming and cell global expression of hPAR(1).	Nitrogen	29-30	coagulation factor II thrombin receptor	Homo sapiens	128-135
21550978-6	2011	Removing these N-linked glycosylation sequons affected hPAR(1) cell surface expression to varying degrees, and N-linked glycosylation at extracellular loop 2 (especially Asn(250)) of hPAR(1) is essential for optimal receptor cell surface expression and receptor stability.	Nitrogen	15-16	coagulation factor II thrombin receptor	Homo sapiens	55-62
20932822-4	2011	Pre-treatment of Nrf2(+/+) MEF cells with 3muM Sul for 18h prior to challenge with xenobiotics, conferred between 2.0- and 4.0-fold protection against isothiocyanates, reactive carbonyls, peroxides, quinones, NaAsO(2), and the anticancer nitrogen mustard chlorambucil, but pre-treatment with 3muM Sul produced no such increased tolerance in Nrf2(-/-) MEF cells.	Nitrogen	238-246	nuclear factor, erythroid derived 2, like 2	Mus musculus	17-21
21507336-0	2011	Enhanced accumulation of secreted human growth hormone by transgenic tobacco cells correlates with the introduction of an N-glycosylation site.	Nitrogen	122-123	growth hormone 1	Homo sapiens	40-54
21507336-3	2011	Inspired by early successes, we tested the possibility of introducing an N-glycosylation site to facilitate the secretion of human growth hormone (hGH) from cultured tobacco cells.	Nitrogen	73-74	growth hormone 1	Homo sapiens	131-145
21784308-0	2011	The relationships between erythrocyte membrane n-6 to n-3 polyunsaturated fatty acids ratio and blood lipids and C-reactive protein in Chinese adults: an observational study.	Nitrogen	11-12	C-reactive protein	Homo sapiens	113-131
21754669-1	2011	In the title compound, [Co(NO(3))(2)(C(18)H(16)N(2)O(2))(2)](n), the Co(II) ion is located on an inversion center and is six-coordinated in an octa-hedral environment defined by four N atoms of the pyridine rings and two O atoms of the nitrate anions.	Nitrogen	27-28	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	69-75
21784308-5	2011	In the top quartile whose ratios of n-6:n-3 increased by an average of 1.25 during the follow-up, the LDL-c-lowering extent was 3.3 times of that in the lowest quartile whose ratios of n-6:n-3 decreased by an average of 1.13 (-1.07 mmol/L v.s.	Nitrogen	1-2	component of oligomeric golgi complex 2	Homo sapiens	102-107
21441208-6	2011	A screen of these deletion mutants revealed GAT1, encoding the only global transcription factor essential for utilization of a wide range of nitrogen sources, including uric acid, urea, and creatinine-three predominant nitrogen constituents found in the C. neoformans ecological niche.	Nitrogen	141-149	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	Mus musculus	44-48
21199819-4	2011	Mutations in the Drosophila alg5 gene wollknauel (wol) that codes for an enzyme initiating the glucosylation of the dolichol-linked oligosaccharide decrease, as expected, glucosylation and the amounts of N-glycosylated proteins such as the cuticle-organizing factor Knickkopf, without affecting their correct localization.	Nitrogen	204-205	wollknaeuel	Drosophila melanogaster	28-32
21199819-4	2011	Mutations in the Drosophila alg5 gene wollknauel (wol) that codes for an enzyme initiating the glucosylation of the dolichol-linked oligosaccharide decrease, as expected, glucosylation and the amounts of N-glycosylated proteins such as the cuticle-organizing factor Knickkopf, without affecting their correct localization.	Nitrogen	204-205	wollknaeuel	Drosophila melanogaster	38-48
21441208-6	2011	A screen of these deletion mutants revealed GAT1, encoding the only global transcription factor essential for utilization of a wide range of nitrogen sources, including uric acid, urea, and creatinine-three predominant nitrogen constituents found in the C. neoformans ecological niche.	Nitrogen	219-227	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	Mus musculus	44-48
21441208-7	2011	In addition to its evolutionarily conserved role in mediating nitrogen metabolite repression and controlling the expression of catabolic enzyme and permease-encoding genes, Gat1 also negatively regulates virulence traits, including infectious basidiospore production, melanin formation, and growth at high body temperature (39 -40 ).	Nitrogen	62-70	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	Mus musculus	173-177
21411530-7	2011	N-glycosylation sites were reintroduced into GP3 and GP5 of FL01, separately or in combination, by site-directed mutagenesis.	Nitrogen	0-1	glycoprotein V platelet	Homo sapiens	53-56
21411530-8	2011	Reintroduction of the N-glycosylation site in either GP3 or GP5 allowed recovery of in vivo and in vitro glycan shielding capacity, with an additive effect when these sites were reintroduced into both glycoproteins simultaneously.	Nitrogen	22-23	glycoprotein V platelet	Homo sapiens	60-63
21515696-0	2011	ABI4 activates DGAT1 expression in Arabidopsis seedlings during nitrogen deficiency.	Nitrogen	64-72	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	0-4
21515696-8	2011	Taken together, our results indicate that abscisic acid signaling is part of the regulatory machinery governing TAG ectopic accumulation and that ABI4 is essential for the activation of DGAT1 in Arabidopsis seedlings during nitrogen deficiency.	Nitrogen	224-232	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	146-150
21521696-1	2011	The Arabidopsis (Arabidopsis thaliana) soluble N-ethylmaleimide-sensitive factor attachment protein receptor SYP41 is involved in vesicle fusion at the trans-Golgi network (TGN) and interacts with AtVPS45, SYP61, and VTI12.	Nitrogen	47-48	syntaxin of plants 41	Arabidopsis thaliana	109-114
21504003-6	2011	The suggested reaction pathways included N-methylation leading to iminium formation in primary and/or secondary amines preceded by cytochrome P450 (CYP)-mediated reactions.	Nitrogen	41-42	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	131-146
21504003-6	2011	The suggested reaction pathways included N-methylation leading to iminium formation in primary and/or secondary amines preceded by cytochrome P450 (CYP)-mediated reactions.	Nitrogen	41-42	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	148-151
21572424-5	2011	We show that APEH inhibition leads to accumulation of N-acetylated proteins and promotes proliferation in T cells.	Nitrogen	54-55	acylaminoacyl-peptide hydrolase	Homo sapiens	13-17
21510625-8	2011	Thus, our results lead us to hypothesize that the low activity and high toxicity of analogues of cisplatin having carrier ligands with N-alkyl groups arise from the low abundance and minimal canting of the HH1 conformer and possibly from the adverse effects of an abundant DeltaHT1 conformer.	Nitrogen	135-136	anosmin 1	Homo sapiens	206-209
21754296-2	2011	The Co(III) atom exhibits an octa-hedral geometry, coordinated by four N atoms from the tris-(2-pyridyl-meth-yl)amine ligand with an average Co-N distance of 1.953 (2) A, and two cyanide C atoms with an average Co-C distance of 1.895 (2) A.	Nitrogen	71-72	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-11
21754318-1	2011	In the title compound, [Co(NO(3))(2)(C(18)H(16)N(2)O(2))], the Co(II) ion is six-coordinated in a distorted octa-hedral environment defined by two O and two N atoms from the ligand and by two O atoms from two nitrate anions.	Nitrogen	27-28	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	63-69
21754296-2	2011	The Co(III) atom exhibits an octa-hedral geometry, coordinated by four N atoms from the tris-(2-pyridyl-meth-yl)amine ligand with an average Co-N distance of 1.953 (2) A, and two cyanide C atoms with an average Co-C distance of 1.895 (2) A.	Nitrogen	144-145	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-11
21244856-2	2011	It is presumed that all 19 mammalian Wnt family members contain two types of post-translational modification: the covalent attachment of fatty acids at two distinct positions, and the N-glycosylation of multiple asparagines.	Nitrogen	184-185	Wnt family member 1	Homo sapiens	37-40
21780594-5	2011	NO2- -N and NO3- -N were nitrogen source for the growth of cyanobacteria and the removal rates were 68.3% and 84.9% , respectively.	Nitrogen	25-33	NBL1, DAN family BMP antagonist	Homo sapiens	12-15
21480587-4	2011	delta15N(NO3) and delta18O(NO3) of catchment surface water and groundwater samples revealed a dominant influence from microbially cycled and nitrified source-nitrogen, which results in high nitrate concentrations in Chalk groundwater and upstream in the River Wensum.	Nitrogen	158-166	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
21480587-4	2011	delta15N(NO3) and delta18O(NO3) of catchment surface water and groundwater samples revealed a dominant influence from microbially cycled and nitrified source-nitrogen, which results in high nitrate concentrations in Chalk groundwater and upstream in the River Wensum.	Nitrogen	158-166	NBL1, DAN family BMP antagonist	Homo sapiens	27-30
21368275-1	2011	[URE3] is a prion (infectious protein) of the Saccharomyces cerevisiae Ure2p, a regulator of nitrogen catabolism.	Nitrogen	93-101	glutathione peroxidase	Saccharomyces cerevisiae S288C	71-76
21368275-3	2011	We find that the Ure2p of Candida albicans and C. glabrata also regulate nitrogen catabolism.	Nitrogen	73-81	glutathione peroxidase	Saccharomyces cerevisiae S288C	17-22
21525989-8	2011	Furthermore, plasma FGF21 level correlated positively with creatinine, blood urea nitrogen (BUN), beta2 microglobulin, systolic pressure, adiponectin, phosphate, proteinuria, CRP and triglyceride, but negatively with creatinine clearance rate (CCR), estimated glomerular filtrate rate (eGFR), HDL-c, LDL-c, albumin and LVH after adjusting for BMI, gender, age and the presence of diabetes mellitus.	Nitrogen	82-90	fibroblast growth factor 21	Homo sapiens	20-25
21380457-1	2011	Human haptoglobin is a serum glycoprotein secreted by the liver with four potential N-glycosylation sites on its beta chain.	Nitrogen	84-85	haptoglobin	Homo sapiens	6-17
21413761-4	2011	Our results indicate that by exploiting their catalytic behavior for O(2) reduction, N-CNTs can efficiently convert toxic CN(-) to the nontoxic OCN(-).	Nitrogen	85-86	bone gamma-carboxyglutamate protein	Homo sapiens	144-147
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	aquaporin-7	Bos taurus	229-233
21362439-10	2011	The potency of this class of hERG channel inhibitors appears to depend on the number and length of their aliphatic side-chains surrounding the charged nitrogen.	Nitrogen	151-159	ETS transcription factor ERG	Homo sapiens	29-33
21173144-7	2011	Both TPC1 and TPC2 are N-glycosylated with residues 599, 611, and 616 contributing to glycosylation of TPC1.	Nitrogen	23-24	two pore segment channel 1	Homo sapiens	5-9
21289055-8	2011	Rats pretreated with IKKbeta siRNA had significantly less blood urea nitrogen and serum creatinine levels and less renal tubular damage scores.	Nitrogen	69-77	inhibitor of nuclear factor kappa B kinase subunit beta	Rattus norvegicus	21-28
25961256-9	2011	Compound 9 forms two H-bonds with 17beta-HSD1: one between the indole nitrogen and His222, and the second between the phenolic OH group and catalytic Tyr155.	Nitrogen	70-78	hydroxysteroid 17-beta dehydrogenase 1	Homo sapiens	34-45
21190512-3	2011	The described effect of TNF-alpha on nitrogen homeostasis may, therefore, depend on IL-6.	Nitrogen	37-45	tumor necrosis factor	Rattus norvegicus	24-33
21190512-3	2011	The described effect of TNF-alpha on nitrogen homeostasis may, therefore, depend on IL-6.	Nitrogen	37-45	interleukin 6	Rattus norvegicus	84-88
21173144-7	2011	Both TPC1 and TPC2 are N-glycosylated with residues 599, 611, and 616 contributing to glycosylation of TPC1.	Nitrogen	23-24	two pore segment channel 1	Homo sapiens	103-107
21106803-8	2011	Similarly, expression of interleukin-1beta, -6 and -8, which were markedly elevated in infected HBCAs, exhibited a significant reduction in their levels in the presence of NS-398.	Nitrogen	172-174	interleukin 1 beta	Homo sapiens	25-53
21385933-7	2011	Immunohistochemical validation of two well-known cellular tumor pathways (TGF-beta and beta-catenin) confirmed that the TGF-beta pathway (positivity of Smad4) was related to N(0) (OR: 0.20, 95% CI: 0.06-0.66) and the beta-catenin pathway (p120 positivity) to N(+) (OR: 1.79, 95%CI: 1.05-3.05).	Nitrogen	259-263	transforming growth factor beta 1	Homo sapiens	120-128
21073985-7	2011	High resolution X-ray photoelectron spectroscopy studies of the scaffolds demonstrated an increase in nitrogen and sulfur due to FN conjugation.	Nitrogen	102-110	fibronectin 1	Homo sapiens	129-131
21030537-0	2011	N-Glycosylation of total cellular glycoproteins from the human ovarian carcinoma SKOV3 cell line and of recombinantly expressed human erythropoietin.	Nitrogen	0-1	erythropoietin	Homo sapiens	134-148
21338809-14	2011	Milk urea nitrogen content was lowered by ADD in experiment 1 and tended to be lower in experiment 2.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
21338813-12	2011	Concentrations of milk urea nitrogen were greater for cows fed RS diets compared with the NS- diet.	Nitrogen	28-36	Weaning weight-maternal milk	Bos taurus	18-22
21146486-0	2011	Selective isolation of N-blocked peptide by combining AspN digestion, transamination, and tosylhydrazine glass treatment.	Nitrogen	23-24	asporin	Homo sapiens	54-58
21248204-2	2011	The yeast homologues Sro7 and Sro77 are thought to act downstream of the Rab GTPase Sec4 to promote soluble N-ethylmaleimide-sensitive factor adaptor protein receptor (SNARE) function in post-Golgi transport.	Nitrogen	108-109	Rab GTPase-binding protein SRO7	Saccharomyces cerevisiae S288C	21-25
21249236-1	2011	NHC ligands annulated to free-base porphyrins can be reversibly switched between electron-poor and electron-rich states upon protonation and deprotonation of the inner nitrogen atoms of the porphyrin.	Nitrogen	168-176	high mobility group nucleosomal binding domain 4	Homo sapiens	0-3
21393836-2	2011	Here, efficient protocols for the production of two ectodomain variants of human Flt3 receptor, Flt3D1-D5 and Flt3D1-D4, for structural studies are reported based on tetracycline-inducible stable cell lines in HEK293S cells deficient in N-acetylglycosaminyltransferase I (GnTI-/-) that can secrete the target proteins with limited and homogeneous N-linked glycosylation to milligram amounts.	Nitrogen	237-238	fms related receptor tyrosine kinase 3	Homo sapiens	81-85
21393836-2	2011	Here, efficient protocols for the production of two ectodomain variants of human Flt3 receptor, Flt3D1-D5 and Flt3D1-D4, for structural studies are reported based on tetracycline-inducible stable cell lines in HEK293S cells deficient in N-acetylglycosaminyltransferase I (GnTI-/-) that can secrete the target proteins with limited and homogeneous N-linked glycosylation to milligram amounts.	Nitrogen	347-348	fms related receptor tyrosine kinase 3	Homo sapiens	81-85
21104290-0	2011	Modulation of E-cadherin function and dysfunction by N-glycosylation.	Nitrogen	53-54	cadherin 1	Homo sapiens	14-24
21104290-4	2011	The present review addresses molecular aspects related to E-cadherin N-glycosylation and evidence is presented showing that the modification of N-linked glycans on E-cadherin can affect the adhesive function of this adhesion molecule.	Nitrogen	69-70	cadherin 1	Homo sapiens	58-68
21104290-4	2011	The present review addresses molecular aspects related to E-cadherin N-glycosylation and evidence is presented showing that the modification of N-linked glycans on E-cadherin can affect the adhesive function of this adhesion molecule.	Nitrogen	69-70	cadherin 1	Homo sapiens	164-174
21104290-6	2011	Finally, this review discusses an alternative functional regulatory mechanism for E-cadherin operating at the post-translational level, N-glycosylation, that may underlie the E-cadherin dysfunction in some carcinomas.	Nitrogen	136-137	cadherin 1	Homo sapiens	82-92
21104290-6	2011	Finally, this review discusses an alternative functional regulatory mechanism for E-cadherin operating at the post-translational level, N-glycosylation, that may underlie the E-cadherin dysfunction in some carcinomas.	Nitrogen	136-137	cadherin 1	Homo sapiens	175-185
20963501-8	2011	Alignment of Izumo1 protein sequences among 15 mammalian species displayed several highly conserved regions, including LDC and YRC motifs with cysteine residues for potential disulfide bridge formation, CPNKCG motif upstream of the Ig-like domain, GLTDYSFYRVW motif upstream of the putative N-linked glycosylation site, and a number of scattered cysteine residues.	Nitrogen	205-206	izumo sperm-egg fusion 1	Homo sapiens	13-19
21191006-0	2011	N-linked glycosylation facilitates sialic acid-independent attachment and entry of influenza A viruses into cells expressing DC-SIGN or L-SIGN.	Nitrogen	0-1	C-type lectin domain family 4 member M	Homo sapiens	136-142
21138438-4	2011	Our results showed that the largest changes in the ecosystem N cycle caused by N addition were increases in soil inorganic N leaching (461%), soil NO3- concentration (429%), nitrification (154%), nitrous oxide emission (134%), and denitrification (84%).	Nitrogen	61-62	NBL1, DAN family BMP antagonist	Homo sapiens	147-150
21510275-5	2011	The phosphorylation levels of p38 (phospho-p38) increased significantly (p &lt; 0.05, n = 3 for each group) in the 10-hour treatment of 100% oxygen at a pressure of 2.3 ATA--which was consistent with time course changes of an apoptosis marker, cleavage caspase-3--while the phospho-p38 decreased in the 10 hours of N2-O2 mixture.	Nitrogen	315-317	mitogen-activated protein kinase 1	Homo sapiens	30-33
20849451-4	2011	The P450 CYP3A4 enzyme is responsible for the major metabolic N-dealkylation pathway.	Nitrogen	62-63	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	9-15
21510275-5	2011	The phosphorylation levels of p38 (phospho-p38) increased significantly (p &lt; 0.05, n = 3 for each group) in the 10-hour treatment of 100% oxygen at a pressure of 2.3 ATA--which was consistent with time course changes of an apoptosis marker, cleavage caspase-3--while the phospho-p38 decreased in the 10 hours of N2-O2 mixture.	Nitrogen	315-317	mitogen-activated protein kinase 1	Homo sapiens	43-46
21510275-5	2011	The phosphorylation levels of p38 (phospho-p38) increased significantly (p &lt; 0.05, n = 3 for each group) in the 10-hour treatment of 100% oxygen at a pressure of 2.3 ATA--which was consistent with time course changes of an apoptosis marker, cleavage caspase-3--while the phospho-p38 decreased in the 10 hours of N2-O2 mixture.	Nitrogen	315-317	mitogen-activated protein kinase 1	Homo sapiens	43-46
21383902-6	2011	Results revealed that the new class of 5-deazapteridine and steroid hybrid compounds VIa,b, and d, and the vertical-type bispyridodipyrimidine with n-hexyl chain junction between its N-10 and N-10 atoms Xa, exhibited non-selective PTK binding capacities, with the lowest (Gb).	Nitrogen	26-27	nuclear receptor subfamily 4 group A member 1	Homo sapiens	183-187
21295282-10	2011	DHDDS is a key enzyme in the pathway of dolichol, which plays an important role in N-glycosylation of many glycoproteins, including rhodopsin.	Nitrogen	83-84	rhodopsin	Homo sapiens	132-141
21383902-6	2011	Results revealed that the new class of 5-deazapteridine and steroid hybrid compounds VIa,b, and d, and the vertical-type bispyridodipyrimidine with n-hexyl chain junction between its N-10 and N-10 atoms Xa, exhibited non-selective PTK binding capacities, with the lowest (Gb).	Nitrogen	26-27	nuclear receptor subfamily 4 group A member 1	Homo sapiens	192-196
21071076-2	2011	To enhance the dermal regeneration, in this study plasmid DNA encoding vascular endothelial growth factor-165 (VEGF-165)/N,N,N-trimethyl chitosan chloride (TMC) complexes were loaded into a bilayer porous collagen-chitosan/silicone membrane dermal equivalents (BDEs), which were applied for treatment of full-thickness burn wounds.	Nitrogen	59-60	vascular endothelial growth factor A	Homo sapiens	111-115
21093406-2	2011	A search in the human genome for methyltransferases capable of catalyzing the N-methylation of benzylisoquinoline alkaloids, as biosynthetic precursors of morphine, yielded two enzymes, PNMT (EC 2.1.1.28) and NMT (EC 2.1.1.49).	Nitrogen	78-79	N-myristoyltransferase 1	Homo sapiens	187-190
21118821-4	2011	This review will mainly focus on these recent advances in the molecular knowledge of N sensing in plants such as the dual function of the nitrate transporter CHL1, the roles of the transcription factors LBD37/38/39 and NLP7 or of the CIPK8/23 kinases, as well as the implication of small RNAs, which are at last opening doors for future research in this field.	Nitrogen	85-86	LOB domain-containing protein 37	Arabidopsis thaliana	203-214
20673806-0	2011	The GATA-type transcriptional activator Gat1 regulates nitrogen uptake and metabolism in the human pathogen Cryptococcus neoformans.	Nitrogen	55-63	solute carrier family 6 member 1	Homo sapiens	40-44
20673806-6	2011	The gat1 mutant exhibited impaired growth on all amino acids tested as sole nitrogen sources, with the exception of arginine and proline.	Nitrogen	76-84	solute carrier family 6 member 1	Homo sapiens	4-8
20673806-7	2011	Furthermore, the gat1 mutant did not display resistance to rapamycin, an immunosuppressant drug that transiently mimics a low-quality nitrogen source.	Nitrogen	134-142	solute carrier family 6 member 1	Homo sapiens	17-21
20673806-9	2011	Microarray analysis allowed the identification of target genes that are regulated by Gat1 in the presence of proline, a poor and non-repressing nitrogen source.	Nitrogen	144-152	solute carrier family 6 member 1	Homo sapiens	85-89
21118821-4	2011	This review will mainly focus on these recent advances in the molecular knowledge of N sensing in plants such as the dual function of the nitrate transporter CHL1, the roles of the transcription factors LBD37/38/39 and NLP7 or of the CIPK8/23 kinases, as well as the implication of small RNAs, which are at last opening doors for future research in this field.	Nitrogen	85-86	CBL-interacting protein kinase 8	Arabidopsis thaliana	234-239
21383973-8	2011	Using primary alpha4beta7/CD4+ T cells and a flow-cytometry based steady-state binding assay we show that the removal of transmission-associated N-linked glycosylation sites results in large increases in the specific reactivity of gp120 for integrin-alpha4beta7.	Nitrogen	145-146	CD4 molecule	Homo sapiens	26-29
22091227-1	2011	BACKGROUND: Insulin-like growth factor 1 (IGF-I) is an anabolic growth factor that affects nitrogen balance and its changing trend is not clearly understood in critically ill patients.	Nitrogen	91-99	insulin like growth factor 1	Homo sapiens	12-40
22091227-1	2011	BACKGROUND: Insulin-like growth factor 1 (IGF-I) is an anabolic growth factor that affects nitrogen balance and its changing trend is not clearly understood in critically ill patients.	Nitrogen	91-99	insulin like growth factor 1	Homo sapiens	42-47
21522843-1	2011	In the title coordination polymer, [Pb(C(7)H(3)NO(4))](n), the Pb(II) ion is eight-coordinated in a distorted square-anti-prismatic geometry formed by one pyridine N atom and seven carboxyl-ate O atoms from four pyridine-2,3-dicarboxyl-ate (pda) anions.	Nitrogen	47-48	submaxillary gland androgen regulated protein 3B	Homo sapiens	63-69
21522869-1	2011	In the title complex, [Co(NCS)(2)(C(13)H(19)N(3)O)(H(2)O)], the Co(II) ion is six-coordinated by the N,N",N""-tridentate Schiff base, the N atoms of two thio-cyanate ligands and one water mol-ecule in a distorted octa-hedral geometry.	Nitrogen	26-27	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	64-70
21522869-1	2011	In the title complex, [Co(NCS)(2)(C(13)H(19)N(3)O)(H(2)O)], the Co(II) ion is six-coordinated by the N,N",N""-tridentate Schiff base, the N atoms of two thio-cyanate ligands and one water mol-ecule in a distorted octa-hedral geometry.	Nitrogen	103-110	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	64-70
21522869-1	2011	In the title complex, [Co(NCS)(2)(C(13)H(19)N(3)O)(H(2)O)], the Co(II) ion is six-coordinated by the N,N",N""-tridentate Schiff base, the N atoms of two thio-cyanate ligands and one water mol-ecule in a distorted octa-hedral geometry.	Nitrogen	44-45	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	64-70
21116921-1	2011	L-arginine is a source of nitric oxide (NO) that is cleaved from the terminal guanidino nitrogen atom by nitric oxide synthase (NOS).	Nitrogen	88-96	nitric oxide synthase 2	Homo sapiens	105-126
21173131-7	2011	The CART model used 6 of 24 variables (iPTH, calcium, creatinine, renal transplantation, percentage of females, and urea nitrogen) and had a misclassification error rate of 0.194 (27/139).	Nitrogen	121-129	CART prepropeptide	Homo sapiens	4-8
21123062-3	2011	Elaboration of a 2-arylaminopyrimidine scaffold led to a series of potent c-Met inhibitors bearing a C4-2-amino-N-methylbenzamide group.	Nitrogen	111-113	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	74-79
21261615-9	2011	These data suggest that syndecan-4 functions in an FGF2-independent manner, and the N-glycosylated and GAG chains are required for syndecan-4 to regulate turkey myogenic satellite cell proliferation, but not differentiation.	Nitrogen	84-85	syndecan-4	Meleagris gallopavo	131-141
21463857-4	2011	WSB-1 associates with the middle part of intracytoplasmic region of IL-21R and enhances the maturation of IL-21R from N-linked glycosylated form to fully glycosylated mature form.	Nitrogen	118-119	interleukin 21 receptor	Homo sapiens	106-112
20731702-2	2011	In our previous studies, tumour necrosis factor-alpha (TNF-alpha) acutely up-regulated the in vivo capacity of urea-nitrogen synthesis (CUNS) in rats before the hepatic acute phase response was established.	Nitrogen	116-124	tumor necrosis factor	Rattus norvegicus	55-64
21097666-4	2011	The SAP2 gene on chromosome R encodes a secreted aspartic protease that is induced and required for growth of C. albicans when proteins are the only available nitrogen source.	Nitrogen	159-167	secretory aspartyl proteinase SAP2p	Candida albicans SC5314	4-8
21097666-9	2011	Replacement of one of the SAP2-1 copies in this strain by SAP2-2 and its regulatory region restored the ability of the sap4Delta sap5Delta sap6Delta mutant to utilize proteins as the sole nitrogen source.	Nitrogen	188-196	secretory aspartyl proteinase SAP2p	Candida albicans SC5314	26-30
21097666-9	2011	Replacement of one of the SAP2-1 copies in this strain by SAP2-2 and its regulatory region restored the ability of the sap4Delta sap5Delta sap6Delta mutant to utilize proteins as the sole nitrogen source.	Nitrogen	188-196	secretory aspartyl proteinase SAP2p	Candida albicans SC5314	58-62
21312365-2	2011	With two N-glycosylation sites, gamma-interferon (IFN-gamma) can be seen as a prototype of a recombinant therapeutic glycoprotein for this purpose.	Nitrogen	9-10	interferon gamma	Homo sapiens	50-59
22026076-8	2011	Peroxisomal oxidases, NAD(P) oxidase, xanthinoxidase, nitric oxide synthase, myeloperoxidase and lipooxygenase catalyze biochemical reactions producing reactive oxygen and nitrogen species.	Nitrogen	172-180	myeloperoxidase	Homo sapiens	77-92
21088568-2	2011	RECENT FINDINGS: There has been continued interest in the potential of oral BCAA supplements in improving energy metabolism, nitrogen metabolism, carbohydrate metabolism, insulin resistance, severity of liver disease, serum albumin levels, quality of serum albumin, or postoperative complication rates.	Nitrogen	125-133	AT-rich interaction domain 4B	Homo sapiens	76-80
21261615-3	2011	Syndecan-4 may derive its biological function from the N-glycosylated chains due to the biological role of N-glycosylated chains in protein folding and cell membrane localization.	Nitrogen	55-56	syndecan-4	Meleagris gallopavo	0-10
21261615-3	2011	Syndecan-4 may derive its biological function from the N-glycosylated chains due to the biological role of N-glycosylated chains in protein folding and cell membrane localization.	Nitrogen	107-108	syndecan-4	Meleagris gallopavo	0-10
21261615-4	2011	The objective of the current study was to investigate the role of syndecan-4 N-glycosylated chains and the interaction between GAG and N-glycosylated chains in turkey myogenic satellite cell proliferation, differentiation, and fibroblast growth factor 2 (FGF2) responsiveness.	Nitrogen	77-78	syndecan-4	Meleagris gallopavo	66-76
21261615-5	2011	The wild type turkey syndecan-4 and the syndecan-4 without GAG chains were cloned into the expression vector pCMS-EGFP and used as templates to generate syndecan-4 N-glycosylated one-chain and no-chain mutants with or without GAG chains.	Nitrogen	164-165	syndecan-4	Meleagris gallopavo	40-50
21261615-5	2011	The wild type turkey syndecan-4 and the syndecan-4 without GAG chains were cloned into the expression vector pCMS-EGFP and used as templates to generate syndecan-4 N-glycosylated one-chain and no-chain mutants with or without GAG chains.	Nitrogen	164-165	syndecan-4	Meleagris gallopavo	40-50
21261615-8	2011	The overexpression of syndecan-4 N-glycosylated mutants with or without GAG chains did not change cell proliferation, differentiation, and responsiveness to FGF2 compared to the wild type syndecan-4 except that the overexpression of syndecan-4 N-glycosylated mutants without GAG chains increased cell proliferation at 48 and 72 h post-transfection.	Nitrogen	33-34	syndecan-4	Meleagris gallopavo	22-32
21261615-8	2011	The overexpression of syndecan-4 N-glycosylated mutants with or without GAG chains did not change cell proliferation, differentiation, and responsiveness to FGF2 compared to the wild type syndecan-4 except that the overexpression of syndecan-4 N-glycosylated mutants without GAG chains increased cell proliferation at 48 and 72 h post-transfection.	Nitrogen	244-245	syndecan-4	Meleagris gallopavo	22-32
21437994-1	2011	Congenital disorder of glycosylation type Ic (CDG-Ic) is caused by mutations in hALG6 gene encoding alpha-1,3 glucosyltransferase (NP_037471.2), an enzyme that catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor in N-glycosylation process.	Nitrogen	131-132	ALG6 alpha-1,3-glucosyltransferase	Homo sapiens	80-85
22272114-0	2011	Structural requirements of N-substituted spiropiperidine analogues as agonists of nociceptin/orphanin FQ receptor.	Nitrogen	27-28	prepronociceptin	Homo sapiens	82-92
21040412-1	2011	BACKGROUND: The anabolic effects of insulin-like growth factor-I (IGF-I) may involve a decrease of hepatic nitrogen (N) clearance, but this has never been studied in humans.	Nitrogen	107-115	insulin like growth factor 1	Homo sapiens	36-64
21040412-1	2011	BACKGROUND: The anabolic effects of insulin-like growth factor-I (IGF-I) may involve a decrease of hepatic nitrogen (N) clearance, but this has never been studied in humans.	Nitrogen	107-115	insulin like growth factor 1	Homo sapiens	66-71
21216945-7	2011	Tap46 depletion reproduced the signature phenotypes of TOR inactivation, such as dramatic repression of global translation and activation of autophagy and nitrogen mobilization, indicating that Tap46 may act as a positive effector of TOR signaling in controlling those processes.	Nitrogen	155-163	target of rapamycin	Arabidopsis thaliana	55-58
21514473-1	2011	Cytochrome c nitrite reductase, NrfA, catalyzes the six-electron reduction of nitrite, NO(2)(-), to ammonium, NH(4)(+), as the final enzymatic step in the dissimilatory metabolic pathway of nitrite ammonification within the biogeochemical nitrogen cycle.	Nitrogen	239-247	cytochrome c, somatic	Homo sapiens	0-12
21629267-4	2011	Downregulation of Mgat1 by IL7RA*C and IL2RA*T is opposed by MGAT1 (IV(A)V(T-T)) and vitamin D(3), optimizing branching and mitigating MS risk when combined with enhanced CTLA-4 N-glycosylation by CTLA-4 Thr17.	Nitrogen	178-179	mannoside acetylglucosaminyltransferase 1	Mus musculus	18-23
21329806-2	2011	UPR transducers IRE1, PERK, ATF6, and UPR-responsive genes such as GRP78/BiP, ERAD genes such as EDEM, and synthesis of the protein N-linked glycosylation donor lipid-linked oligosaccharides (LLOs) are mobilized.	Nitrogen	132-133	heat shock protein family A (Hsp70) member 5	Homo sapiens	67-72
21329806-2	2011	UPR transducers IRE1, PERK, ATF6, and UPR-responsive genes such as GRP78/BiP, ERAD genes such as EDEM, and synthesis of the protein N-linked glycosylation donor lipid-linked oligosaccharides (LLOs) are mobilized.	Nitrogen	132-133	heat shock protein family A (Hsp70) member 5	Homo sapiens	73-76
21216945-7	2011	Tap46 depletion reproduced the signature phenotypes of TOR inactivation, such as dramatic repression of global translation and activation of autophagy and nitrogen mobilization, indicating that Tap46 may act as a positive effector of TOR signaling in controlling those processes.	Nitrogen	155-163	target of rapamycin	Arabidopsis thaliana	234-237
21633500-2	2011	Prior studies have shown that the double N-methylated analogue of islet amyloid polypeptide (IAPP) IAPP-GI, which is a conformationally constrained IAPP analogue mimicking a non-amyloidogenic IAPP conformation, is capable of blocking cytotoxic self-assembly of Abeta.	Nitrogen	41-42	amyloid beta precursor protein	Homo sapiens	261-266
22110713-9	2011	Asrij mutant lymph glands show increased N in sorting endosomes suggesting aberrant trafficking.	Nitrogen	41-42	asrij	Drosophila melanogaster	0-5
21912684-2	2011	The Gap1 general amino acid permease and the Mep2 ammonium permease mediate rapid activation by amino acids and by ammonium, respectively, of the protein kinase A (PKA) pathway in nitrogen-starved cells.	Nitrogen	180-188	amino acid permease GAP1	Saccharomyces cerevisiae S288C	4-8
21701691-9	2011	Our results suggest that chronic atmospheric N deposition may lower decomposition rates through a combination of reduced expression of ligninolytic genes such as lcc, and compositional changes in the fungal community.	Nitrogen	45-46	small nucleolar RNA, C/D box 118	Homo sapiens	162-165
22016782-1	2011	Acylpeptide hydrolase (APEH), one of the four members of the prolyl oligopeptidase class, catalyses the removal of N-acylated amino acids from acetylated peptides and it has been postulated to play a key role in protein degradation machinery.	Nitrogen	115-116	acylaminoacyl-peptide hydrolase	Homo sapiens	0-21
22016782-1	2011	Acylpeptide hydrolase (APEH), one of the four members of the prolyl oligopeptidase class, catalyses the removal of N-acylated amino acids from acetylated peptides and it has been postulated to play a key role in protein degradation machinery.	Nitrogen	115-116	acylaminoacyl-peptide hydrolase	Homo sapiens	23-27
21289492-3	2011	In yeast, nitrogen and/or carbon limitation causes downregulation of the conserved TORC1 and PKA signaling pathways and consequently activation of Rim15, a member of the PAS protein kinase family.	Nitrogen	10-18	protein kinase RIM15	Saccharomyces cerevisiae S288C	147-152
21076138-2	2011	Ure2, the nitrogen metabolism regulation factor of Saccharomyces cerevisiae, shows prion properties in vivo and forms amyloid fibrils in vitro.	Nitrogen	10-18	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-4
21411937-1	2011	To improve the efficiency of low-strength domestic wastewater treatment, an immobilised-microorganism biological aerated filter (I-BAF) was established for simultaneous carbon, nitrogen and phosphorus removal.	Nitrogen	177-185	BAF nuclear assembly factor 1	Homo sapiens	131-134
20868657-3	2010	Furthermore, we investigated whether feeding a diet of n-3 PUFA ethyl-eicosapentaenoate (E-EPA) to these mice can attenuate the MPP(+) induced changes in brain PUFA content and expression of cPLA2 and COX-2, and attenuate MPP(+) induced changes in neurotransmitters and metabolites and apoptotic markers, bax, bcl-2 and caspase-3.	Nitrogen	17-18	B cell leukemia/lymphoma 2	Mus musculus	310-315
21203500-0	2010	Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1alpha as a master regulator of plasma protein fucosylation.	Nitrogen	55-56	HNF1 homeobox A	Homo sapiens	76-85
21062008-5	2010	We used NMR spectroscopy of (15)N-labeled HBD2 to map the binding sites for two GAG model compounds, a heparin/HS pentasaccharide (fondaparinux sodium; FX) and enzymatically prepared DS hexasaccharide (DSdp6).	Nitrogen	8-9	defensin beta 4A	Homo sapiens	42-46
21125574-8	2010	The R=P(OPh)(3) complex was most reactive due to its pi-acid character, which favors the rupture of the trans nitrogen-palladium bond in the A-2 mechanism and also that of the pyridine nitrogen-palladium bond in the A-1 mechanism.	Nitrogen	110-118	ATPase H+ transporting V0 subunit a2	Homo sapiens	141-144
21125574-8	2010	The R=P(OPh)(3) complex was most reactive due to its pi-acid character, which favors the rupture of the trans nitrogen-palladium bond in the A-2 mechanism and also that of the pyridine nitrogen-palladium bond in the A-1 mechanism.	Nitrogen	110-118	BCL2 related protein A1	Homo sapiens	216-219
20705919-12	2010	Our findings demonstrate that a decreased n-6/n-3 fatty acid ratio reduces atherosclerotic lesions in apoE(-/-) mice.	Nitrogen	6-7	apolipoprotein E	Mus musculus	102-106
20399272-9	2010	In particular, an 88 amino acid tryptic peptide covering the presumed substrate binding domains HP1, TMD7, HP2, and TMD8 domains of EAAT2 was also identified after N-deglycosylation.	Nitrogen	164-165	solute carrier family 1 member 2	Homo sapiens	132-137
21107524-2	2010	Mostly, NO3- was the dominant species of DIN (Dissolved Inorganic Nitrogen), although NH4+ was the main species in certain samples, such as sewage.	Nitrogen	66-74	NBL1, DAN family BMP antagonist	Homo sapiens	8-11
20937029-9	2010	Based upon the understanding of molecular interaction of Ang II receptor antagonists with AT(1) receptor some of the common structural features have been identified, such as a heterocyclic (nitrogen atom) ring system, an alkyl side chain and an acidic tetrazole group.	Nitrogen	190-198	angiotensinogen	Homo sapiens	57-63
20980671-0	2010	Mechanism of N-methylation by the tRNA m1G37 methyltransferase Trm5.	Nitrogen	13-14	tRNA methyltransferase 5	Homo sapiens	63-67
20880842-0	2010	Ure2 is involved in nitrogen catabolite repression and salt tolerance via Ca2+ homeostasis and calcineurin activation in the yeast Hansenula polymorpha.	Nitrogen	20-28	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-4
21589279-2	2010	One Co(II) atom is coordinated by three O atoms from the three 2-hy-droxy-ethyl-pyridine (HEP) bridging ligands, two N atoms from two HEP ligands and one azido ligand, while the other Co(II) atom is coordinated by the same three O atoms, one N atom from an HEP ligand and two azido ligands.	Nitrogen	117-118	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
21589279-2	2010	One Co(II) atom is coordinated by three O atoms from the three 2-hy-droxy-ethyl-pyridine (HEP) bridging ligands, two N atoms from two HEP ligands and one azido ligand, while the other Co(II) atom is coordinated by the same three O atoms, one N atom from an HEP ligand and two azido ligands.	Nitrogen	242-243	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
20820497-4	2010	Using capillary electrophoresis-based selection, we have developed DNA aptamer sequences that selectively bind an N-glycosylated peptide fragment of vascular endothelial growth factor (VEGF).	Nitrogen	68-69	vascular endothelial growth factor A	Homo sapiens	149-183
20820497-4	2010	Using capillary electrophoresis-based selection, we have developed DNA aptamer sequences that selectively bind an N-glycosylated peptide fragment of vascular endothelial growth factor (VEGF).	Nitrogen	68-69	vascular endothelial growth factor A	Homo sapiens	185-189
20977456-0	2010	Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes.	Nitrogen	42-43	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	28-34
20699408-1	2010	Purification of the mitochondrial enzyme responsible for reduction of N-hydroxylated amidine prodrugs led to the identification of two newly discovered mammalian molybdenum-containing proteins, the mitochondrial amidoxime reducing components mARC-1 and mARC-2 (Gruenewald et al., 2008).	Nitrogen	70-71	mitochondrial amidoxime reducing component 2	Mus musculus	242-248
20699408-1	2010	Purification of the mitochondrial enzyme responsible for reduction of N-hydroxylated amidine prodrugs led to the identification of two newly discovered mammalian molybdenum-containing proteins, the mitochondrial amidoxime reducing components mARC-1 and mARC-2 (Gruenewald et al., 2008).	Nitrogen	70-71	mitochondrial amidoxime reducing component 2	Mus musculus	253-259
20713656-3	2010	Among the 12 UGT isoforms tested, the O- and N-glucuronidation of 1"-hydroxymidazolam was mediated by UGT2B4/2B7 and 1A4, respectively.	Nitrogen	45-46	UDP glucuronosyltransferase family 2 member B4	Homo sapiens	102-108
21284318-2	2010	Nitrogen cycling within the CW was driven by settlement and mineralization of particulate organic nitrogen and uptake of NO3-.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	121-124
20708014-8	2010	Furthermore, inhibition of COX-2 activity by either NS-398 or DUP-697 partially offset protective effects of the miR-144/451 cluster.	Nitrogen	52-54	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	27-32
20708014-8	2010	Furthermore, inhibition of COX-2 activity by either NS-398 or DUP-697 partially offset protective effects of the miR-144/451 cluster.	Nitrogen	52-54	microRNA 144	Homo sapiens	113-120
20826224-0	2010	A functional analysis of N-glycosylation-related genes on sialylation of recombinant erythropoietin in six commonly used mammalian cell lines.	Nitrogen	25-26	erythropoietin	Homo sapiens	85-99
20826224-2	2010	Here, we report a systematic functional analysis of 31 N-glycosylation-related genes on sialylation of recombinant EPO in six cell lines.	Nitrogen	55-56	erythropoietin	Homo sapiens	115-118
20860552-4	2010	PEMT-L, but not PEMT-S, was N-glycosylated with high-mannose oligosaccharides.	Nitrogen	28-29	phosphatidylethanolamine N-methyltransferase	Homo sapiens	0-4
20943290-3	2010	Unsubstituted pyrrole derivatives bearing a tert-alkyl chain at the 3-carboxamide nitrogen showed greater hCB1 receptor affinity than the corresponding unbranched compounds.	Nitrogen	82-90	cannabinoid receptor 1	Homo sapiens	106-110
22314953-8	2010	Also, CCL4 produced significant increase in serum blood urea nitrogen (BUN) and creatinine compared with normal rats.	Nitrogen	61-69	C-C motif chemokine ligand 4	Rattus norvegicus	6-10
21085684-13	2010	Intense PLD4 expression was detected around the marginal zone of the splenic red pulp, and splenic PLD4 protein recovered from subcellular membrane fractions was highly N-glycosylated.	Nitrogen	169-170	phospholipase D family, member 4	Mus musculus	99-103
20739279-0	2010	N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.	Nitrogen	0-1	cell adhesion molecule 1	Homo sapiens	23-29
20739279-0	2010	N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion.	Nitrogen	0-1	cell adhesion molecule 1	Homo sapiens	31-62
20739279-4	2010	Here, we demonstrate that site-specific N-glycosylation impacts the structure and function of adhesive SynCAM interactions.	Nitrogen	40-41	cell adhesion molecule 1	Homo sapiens	103-109
20739279-11	2010	Functionally, N-glycosylation promotes the trans-synaptic interactions of SynCAM 1 and is required for synapse induction.	Nitrogen	14-15	cell adhesion molecule 1	Homo sapiens	74-82
20739279-12	2010	These results demonstrate that N-glycosylation of SynCAM proteins differentially affects their binding interface and implicate post-translational modification as a mechanism to regulate trans-synaptic adhesion.	Nitrogen	31-32	cell adhesion molecule 1	Homo sapiens	50-56
20826563-0	2010	N-glycosylation increases the circulatory half-life of human growth hormone.	Nitrogen	0-1	growth hormone 1	Homo sapiens	61-75
20619539-1	2010	Samarium and nitrogen co-doped titania (Sm/N-TiO(2)) was successfully prepared via coprecipitation method.	Nitrogen	13-21	small nuclear ribonucleoprotein polypeptide N	Homo sapiens	40-44
21588853-1	2010	The Pb(II )atom in the title compound, {[Pb(2)(C(7)H(6)NO(2))(4)]}(n), is chelated by two 3-aminobenzoato ligands in a distorted pentagonal-bipyramidal coordination geometry with five oxygen donors in the equatorial positions, one nitro-gen donor and one oxygen donor in the axial positions.	Nitrogen	231-240	submaxillary gland androgen regulated protein 3B	Homo sapiens	4-11
20937885-0	2010	Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus.	Nitrogen	22-30	amino acid permease GAP1	Saccharomyces cerevisiae S288C	109-113
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	18-22
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	96-100
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	101-107
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	113-122
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	157-165	amino acid permease GAP1	Saccharomyces cerevisiae S288C	18-22
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	157-165	amino acid permease GAP1	Saccharomyces cerevisiae S288C	96-100
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	157-165	amino acid permease GAP1	Saccharomyces cerevisiae S288C	101-107
20937885-10	2010	The high level of GAP1 expression in nitrogen-limited chemostats suggests that the frequency of GAP1(circle) and gap1Delta generation may be increased under nitrogen-limiting conditions.	Nitrogen	157-165	amino acid permease GAP1	Saccharomyces cerevisiae S288C	113-122
20739461-6	2010	During nitrogen starvation, Npr1 phosphorylation of Aly2 may stimulate Gap1 incorporation into AP-1/clathrin-coated vesicles to promote Gap1 trafficking from endosomes to the trans-Golgi network.	Nitrogen	7-15	Aly2p	Saccharomyces cerevisiae S288C	52-56
20815339-2	2010	N-Linked glycosylation of human IL-7Ralpha enhances its binding affinity for human IL-7 300-fold versus that of the nonglycosylated receptor through an allosteric mechanism.	Nitrogen	0-1	interleukin 7	Homo sapiens	32-36
20822184-0	2010	Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as alpha4beta2-nicotinic acetylcholine receptor-selective partial agonists.	Nitrogen	56-64	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	173-205
20844196-7	2010	In response to cisplatin treatment, IL-10 knockout mice showed more rapid and greater increases in blood urea nitrogen and serum creatinine compared with wild-type mice, indicating that endogenous IL-10 ameliorates kidney injury in cisplatin nephrotoxicity.	Nitrogen	110-118	interleukin 10	Mus musculus	36-41
20844196-7	2010	In response to cisplatin treatment, IL-10 knockout mice showed more rapid and greater increases in blood urea nitrogen and serum creatinine compared with wild-type mice, indicating that endogenous IL-10 ameliorates kidney injury in cisplatin nephrotoxicity.	Nitrogen	110-118	interleukin 10	Mus musculus	197-202
20730242-0	2010	Zwitterionic and cationic P(5)-clusters from four-membered phosphorus-nitrogen-metal heterocycles.	Nitrogen	70-78	solute carrier family 10 member 5	Homo sapiens	26-30
20693288-9	2010	Furthermore, up-regulation of DPAGT1 transcripts by Wnt3a led to altered N-glycosylation of E-cadherin.	Nitrogen	73-74	cadherin 1	Homo sapiens	92-102
20831162-1	2010	A variety of spectroscopic techniques combined with in situ pressure-controlled X-ray diffraction and molecular simulations have been utilized to characterize the five-step phase transition observed upon N(2) adsorption within the high-surface area metal-organic framework Co(BDP) (BDP(2-) = 1,4-benzenedipyrozolate).	Nitrogen	204-208	AT-rich interaction domain 3B	Homo sapiens	231-280
20831162-1	2010	A variety of spectroscopic techniques combined with in situ pressure-controlled X-ray diffraction and molecular simulations have been utilized to characterize the five-step phase transition observed upon N(2) adsorption within the high-surface area metal-organic framework Co(BDP) (BDP(2-) = 1,4-benzenedipyrozolate).	Nitrogen	204-208	AT-rich interaction domain 3B	Homo sapiens	276-279
20831162-5	2010	Based on the enthalpy, a weak N(2) interaction with the open Co(II) coordination sites is proposed for the first four phases, which is supported by Monte Carlo simulations.	Nitrogen	30-34	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	61-66
20727522-9	2010	N-3 supplementation also decreased the lymphocyte, monocyte, TNF-alpha, IL-6 and IL-1beta levels.	Nitrogen	0-1	tumor necrosis factor	Homo sapiens	61-70
20727522-9	2010	N-3 supplementation also decreased the lymphocyte, monocyte, TNF-alpha, IL-6 and IL-1beta levels.	Nitrogen	0-1	interleukin 6	Homo sapiens	72-76
20727522-9	2010	N-3 supplementation also decreased the lymphocyte, monocyte, TNF-alpha, IL-6 and IL-1beta levels.	Nitrogen	0-1	interleukin 1 beta	Homo sapiens	81-89
20732813-0	2010	Utilization of a nitrogen-sulfur nonbonding interaction in the design of new 2-aminothiazol-5-yl-pyrimidines as p38alpha MAP kinase inhibitors.	Nitrogen	17-25	mitogen-activated protein kinase 14	Homo sapiens	112-120
20621206-4	2010	MPO has 5 N-linked glycosylation sites, occupied by both high mannose and complex glycan structures.	Nitrogen	10-11	myeloperoxidase	Homo sapiens	0-3
20732813-2	2010	These efforts led to the identification of 41 as a potent p38alpha inhibitor that utilizes a unique nitrogen-sulfur intramolecular nonbonding interaction to stabilize the conformation required for binding to the p38alpha active site.	Nitrogen	100-108	mitogen-activated protein kinase 14	Homo sapiens	58-66
20732813-2	2010	These efforts led to the identification of 41 as a potent p38alpha inhibitor that utilizes a unique nitrogen-sulfur intramolecular nonbonding interaction to stabilize the conformation required for binding to the p38alpha active site.	Nitrogen	100-108	mitogen-activated protein kinase 14	Homo sapiens	212-220
20632333-4	2010	The molecular structure of the free ligand H(6)chand(rac) exhibits at the terminal donor sides the O-protonated phenol-imine tautomer and at the central donor sides the N-protonated keto-enamine tautomer.	Nitrogen	169-170	AKT serine/threonine kinase 1	Homo sapiens	43-57
20954089-3	2010	The drift tube temperature of the ELSD system was set at 115  C and the nitrogen flow rate was 2.8 L min-1.	Nitrogen	72-80	CD59 molecule (CD59 blood group)	Homo sapiens	101-106
20927321-5	2010	Our studies have shown that the n-3 PUFA species, docosahexaenoic acid (DHA), increases SDC-1 expression in prostate tissues of Pten knockout (Pten(P-/-)) mice/cells and human prostate cancer cells.	Nitrogen	21-22	phosphatase and tensin homolog	Mus musculus	128-132
20927321-10	2010	A diet enriched in n-3 PUFA decreased phosphorylation of PDK1, Akt (T308), and Bad in prostates of Pten(P-/-) mice.	Nitrogen	8-9	pyruvate dehydrogenase kinase, isoenzyme 1	Mus musculus	57-61
20927321-10	2010	A diet enriched in n-3 PUFA decreased phosphorylation of PDK1, Akt (T308), and Bad in prostates of Pten(P-/-) mice.	Nitrogen	8-9	thymoma viral proto-oncogene 1	Mus musculus	63-66
20927321-10	2010	A diet enriched in n-3 PUFA decreased phosphorylation of PDK1, Akt (T308), and Bad in prostates of Pten(P-/-) mice.	Nitrogen	8-9	phosphatase and tensin homolog	Mus musculus	99-103
20715268-4	2010	Our results suggest that bilayer interface localization of the N-alkyl chain in the R(2) position of the DAG-lactones inhibits translocation of PKC isoenzymes onto the cellular membrane.	Nitrogen	63-64	proline rich transmembrane protein 2	Homo sapiens	144-147
20715813-10	2010	The pFe values of 26.5 for N(3)(etLH)(3) and 24.78 for N(2)(prLH)(2) are comparable to other siderophore molecules used in the treatment of iron overload, suggesting that these hydroxypyridinone ligands may be useful in the development of new chelation therapy agents.	Nitrogen	55-59	prolactin releasing hormone	Homo sapiens	60-64
21049883-4	2010	The delta15N and delta18O of stream NO3- varied significantly between urban, agricultural, and forested watersheds, indicating that nitrogen sources are the primary determinant of the delta15N-NO3-, while the delta18O-NO3- was found to reflect biogeochemical processes.	Nitrogen	132-140	NBL1, DAN family BMP antagonist	Homo sapiens	36-39
21049883-4	2010	The delta15N and delta18O of stream NO3- varied significantly between urban, agricultural, and forested watersheds, indicating that nitrogen sources are the primary determinant of the delta15N-NO3-, while the delta18O-NO3- was found to reflect biogeochemical processes.	Nitrogen	132-140	NBL1, DAN family BMP antagonist	Homo sapiens	193-196
21049883-4	2010	The delta15N and delta18O of stream NO3- varied significantly between urban, agricultural, and forested watersheds, indicating that nitrogen sources are the primary determinant of the delta15N-NO3-, while the delta18O-NO3- was found to reflect biogeochemical processes.	Nitrogen	132-140	NBL1, DAN family BMP antagonist	Homo sapiens	193-196
21587471-2	2010	The Co(II) cation is in a distorted octa-hedral environment, coordinated by four sulfonate O atoms and two N atoms from the taurine ligands.	Nitrogen	107-108	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
20605848-1	2010	Deficiency of subunit 6 of the conserved oligomeric Golgi (COG6) complex causes a new combined N- and O-glycosylation deficiency of the congenital disorders of glycosylation, designated as CDG-IIL (COG6-CDG).	Nitrogen	95-96	component of oligomeric golgi complex 6	Homo sapiens	59-63
20605848-1	2010	Deficiency of subunit 6 of the conserved oligomeric Golgi (COG6) complex causes a new combined N- and O-glycosylation deficiency of the congenital disorders of glycosylation, designated as CDG-IIL (COG6-CDG).	Nitrogen	95-96	component of oligomeric golgi complex 6	Homo sapiens	198-202
20535121-8	2010	Furthermore, serum PlGF concentrations of pre-eclamptic patients showed significant positive correlations with gestational age at disease onset and delivery, as well as with fetal birth weight, and significant inverse correlations with levels of blood urea nitrogen, creatinine and fibronectin.	Nitrogen	257-265	placental growth factor	Homo sapiens	19-23
20608986-2	2010	Rot1 is an N-glycosylated protein anchored to the nuclear envelope-endoplasmic reticulum (ER) membrane by a transmembrane domain at its C-terminal end.	Nitrogen	11-12	Rot1p	Saccharomyces cerevisiae S288C	0-4
20695889-2	2010	A coordinated remodeling of N- and O-glycosylation, and an increase in the presentation of the endogenous lectin galectin-1 sensing these changes on the surface of p16(INK4a)-expressing pancreatic carcinoma cells (Capan-1), lead to potent pro-anoikis signals.	Nitrogen	28-29	cyclin dependent kinase inhibitor 2A	Homo sapiens	164-167
20695889-2	2010	A coordinated remodeling of N- and O-glycosylation, and an increase in the presentation of the endogenous lectin galectin-1 sensing these changes on the surface of p16(INK4a)-expressing pancreatic carcinoma cells (Capan-1), lead to potent pro-anoikis signals.	Nitrogen	28-29	cyclin dependent kinase inhibitor 2A	Homo sapiens	168-173
21588525-1	2010	In the title compound, [Co(C(19)H(13)ClN(3)O)(2)]NO(3) 2CH(3)OH, the central Co(III) atom in the cation is surrounded by two tridentate ligands in a distorted octa-hedral fashion by four N and two O atoms.	Nitrogen	39-40	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	77-84
20554523-4	2010	Furthermore, we found that binding to polyglutamine aggregates requires a previously uncharacterized glutamine/asparagine (Q/N)-rich region in the C-terminal domain of TDP-43.	Nitrogen	125-126	TAR DNA binding protein	Homo sapiens	168-174
20890097-2	2010	Here we investigated by real time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16 and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles.	Nitrogen	140-148	sulfate adenylyltransferase	Saccharomyces cerevisiae S288C	80-84
20890097-2	2010	Here we investigated by real time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16 and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles.	Nitrogen	140-148	sulfite reductase (NADPH) subunit beta	Saccharomyces cerevisiae S288C	91-96
20890097-2	2010	Here we investigated by real time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16 and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles.	Nitrogen	140-148	phosphoadenylyl-sulfate reductase (thioredoxin)	Saccharomyces cerevisiae S288C	105-110
20890097-2	2010	Here we investigated by real time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16 and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles.	Nitrogen	140-148	bifunctional cysteine synthase/O-acetylhomoserine aminocarboxypropyltransferase MET17	Saccharomyces cerevisiae S288C	115-120
21588529-2	2010	The Co(II) atom (site symmetry 2) is six-coordinate in a distorted octahedral configuration bonded by two N and two O atoms from two (2-amino-phen-yl)methanol ligands and two O atoms from the two nitrate anions.	Nitrogen	106-107	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
20518742-5	2010	Membrane-associated matriptase-2 is highly N-glycosylated and occurs in monomeric, as well as multimeric, forms covalently linked by disulfide bonds.	Nitrogen	43-44	transmembrane serine protease 6	Homo sapiens	20-32
20590088-1	2010	Bioisoteric replacement of the metabolically labile N-methyl amide group of a series of benzoxazinones with small heterocyclic rings has led to novel series of fused tricyclic benzoxazines which are potent 5-HT(1A/B/D) receptor antagonists with and without concomitant human serotonin transporter (hSerT) activity.	Nitrogen	52-53	solute carrier family 6 member 4	Homo sapiens	275-296
20659803-4	2010	These peptides, corresponding to N-methylated analogues of residues 16-21 and 32-37 of the Abeta-peptide, pathological hallmark of Alzheimer"s disease (AD), have previously been shown to inhibit aggregation of Abeta fibrils in vitro.	Nitrogen	33-34	amyloid beta precursor protein	Homo sapiens	91-96
20590088-1	2010	Bioisoteric replacement of the metabolically labile N-methyl amide group of a series of benzoxazinones with small heterocyclic rings has led to novel series of fused tricyclic benzoxazines which are potent 5-HT(1A/B/D) receptor antagonists with and without concomitant human serotonin transporter (hSerT) activity.	Nitrogen	52-53	solute carrier family 6 member 4	Homo sapiens	298-303
20957167-3	2010	In the case of both N/P ratios (5, 25), nanoparticles started releasing EGFR antisense as soon as they were exposed to the medium and the release lasted for approximately 50 hours.	Nitrogen	20-21	epidermal growth factor receptor	Homo sapiens	72-76
20957167-6	2010	Agarose gel electrophoresis of the nanoparticles with the two different N/P ratios showed that these nanoparticles could protect EGFR antisense molecules for six hours.	Nitrogen	72-73	epidermal growth factor receptor	Homo sapiens	129-133
20582414-10	2010	Low NO(3) (-)-N contents could mean a substantial microbial assimilation of NO(3) (-)-N, constituting an important mechanism for nitrogen retention.	Nitrogen	129-137	NBL1, DAN family BMP antagonist	Homo sapiens	4-9
20532401-3	2010	The most potent inhibitor was a 4-carboxypyridone analogue bearing a lactate side chain on the pyridyl nitrogen which exhibited inhibition constants of 5, 91 and 54 muM against anthranilate synthase, isochorismate synthase and salicylate synthase respectively.	Nitrogen	103-111	latexin	Homo sapiens	165-168
20621490-5	2010	Besides an important interaction between the protonated nitrogen of the C1 alkyl analogs and residue Asp155, we identified Ser242, Phe234, and Gly238 as key residues responsible for the affinity of these compounds for the 5-HT(2A) receptor.	Nitrogen	56-64	5-hydroxytryptamine receptor 2A	Homo sapiens	222-239
20593850-0	2010	Superbasic amidine monodentate ligands in fac-[Re(CO)3(5,5"-Me2bipy)(amidine)]BF4 complexes: dependence of amidine configuration on the remote nitrogen substituents.	Nitrogen	143-151	FA complementation group C	Homo sapiens	42-45
20403411-3	2010	In previous studies, we have demonstrated that the introduction of four N-glycosylation sites in order to construct a heavily glycosylated IFN variant (4N-IFN) resulted in a markedly prolonged plasma half-life which was reflected in an enhanced therapeutic activity in mice in comparison with the commercial non-glycosylated rhIFN-alpha2b (NG-IFN).	Nitrogen	72-73	interferon alpha 1	Homo sapiens	139-142
20403411-3	2010	In previous studies, we have demonstrated that the introduction of four N-glycosylation sites in order to construct a heavily glycosylated IFN variant (4N-IFN) resulted in a markedly prolonged plasma half-life which was reflected in an enhanced therapeutic activity in mice in comparison with the commercial non-glycosylated rhIFN-alpha2b (NG-IFN).	Nitrogen	72-73	interferon alpha 1	Homo sapiens	155-158
20403411-3	2010	In previous studies, we have demonstrated that the introduction of four N-glycosylation sites in order to construct a heavily glycosylated IFN variant (4N-IFN) resulted in a markedly prolonged plasma half-life which was reflected in an enhanced therapeutic activity in mice in comparison with the commercial non-glycosylated rhIFN-alpha2b (NG-IFN).	Nitrogen	72-73	interferon alpha 1	Homo sapiens	155-158
20582414-10	2010	Low NO(3) (-)-N contents could mean a substantial microbial assimilation of NO(3) (-)-N, constituting an important mechanism for nitrogen retention.	Nitrogen	129-137	NBL1, DAN family BMP antagonist	Homo sapiens	76-81
20618438-0	2010	N-glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding.	Nitrogen	0-1	transferrin	Homo sapiens	120-131
20435351-7	2010	In the Ac-neurokinin A case copper(II) coordination starts from the imidazole nitrogen of the His; afterwards three deprotonated amide nitrogens are progressively involved in copper coordination.	Nitrogen	78-86	tachykinin precursor 1	Homo sapiens	10-22
20704612-8	2010	However, the MPO-ANCA-positive group showed a higher level of blood urea nitrogen and proteinuria than those negative for MPO-ANCA.	Nitrogen	73-81	myeloperoxidase	Homo sapiens	13-16
19557535-2	2010	The main nitrogen compounds in the atmosphere include gaseous N (NH3, NO2, HNO3) and aerosol N (NH4+/NO3-).	Nitrogen	9-17	NBL1, DAN family BMP antagonist	Homo sapiens	76-79
20508903-8	2010	In the light of this new vision on the critical role played by the cross-talk between n/eNOS and iNOS as well as the non enzymatic NO production by nitrite, we have reason to believe that new pharmacological measurements or experimental interventions, such as ischaemic preconditioning, aimed at counteracting the drop in NO levels beyond the normal range of NO homeostasis during early reperfusion can represent an efficient strategy to reduce the extent of functional impairment and cardiac damage in the heart exposed to ischaemia/reperfusion injury.	Nitrogen	1-2	nitric oxide synthase 2	Homo sapiens	97-101
20637498-6	2010	Our results thus suggest that SRD5A3 is likely to be the long-sought polyprenol reductase and reveal the genetic basis of one of the earliest steps in protein N-linked glycosylation.	Nitrogen	159-160	steroid 5 alpha-reductase 3	Homo sapiens	30-36
20418283-0	2010	Specific N-linked glycosylation sites modulate synthesis and secretion of von Willebrand factor.	Nitrogen	9-10	von Willebrand factor	Homo sapiens	74-95
20418283-3	2010	To determine whether specific glycosylation sites were important, the 16 VWF N-linked glycosylation sites were mutated followed by expression in HEK293T cells.	Nitrogen	77-78	von Willebrand factor	Homo sapiens	73-76
20543108-2	2010	Membrane fusion events that are mediated by soluble N-ethylmaleimide-sensitive-factor attachment protein receptor (SNARE) proteins are crucial, as demonstrated by patients with familial hemophagocytic lymphohistocytosis type 4 who have mutations in the SNARE protein syntaxin-11 that result in an impaired degranulation of cytotoxic cells.	Nitrogen	52-53	syntaxin 11	Homo sapiens	267-278
21588176-1	2010	The Pb(II) atom in the title compound, [Pb(C(10)H(6)NO(2))(2)], is N,O-chelated by two quinoline-2-carboxyl-ate anions in a distorted Psi-trigonal-bipyramidal environment; four atoms are connected to the Pb(II) atom by regular coordination bonds.	Nitrogen	52-53	submaxillary gland androgen regulated protein 3B	Homo sapiens	4-10
20655849-1	2010	N-glycosylation of the I-like domain of beta1 integrin plays an essential role in integrin structure and function, and the altered sialylation of beta1 integrin regulates beta1 integrin binding to fibronectin.	Nitrogen	0-1	fibronectin 1	Homo sapiens	197-208
20515078-2	2010	VEGF protein silencing peaked at 94% when cationic lipid-nucleic acid complexes (lipoplexes) were formulated at a nitrogen:phosphorothioate ratio (N:P) of 2 with a dose concentration of 53.7 nM, and the performance of these lipoplexes was not impeded by serum.	Nitrogen	114-122	vascular endothelial growth factor A	Homo sapiens	0-4
20618991-9	2010	N-glycosylation inhibitor tunicamycin was used to deglycosylate the integrin beta1 subunit.	Nitrogen	0-1	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	77-82
20825018-7	2010	And the contents of inorganic nitrogen in pond water and sediment displayed a following order: NH4+ -N &gt; NO3- -N &gt; NO2- -N. Data analysis indicated that there was a significantly positive correlation between organic matter and total nitrogen and phosphorus in water and sediment.	Nitrogen	30-38	NBL1, DAN family BMP antagonist	Homo sapiens	108-111
19897389-11	2010	CONCLUSIONS: Clarithromycin strongly increases plasma concentrations of oral S-ketamine probably by inhibiting its CYP3A-mediated N-demethylation.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	115-120
20685471-2	2010	The Ga(III) ion-imprinted/multi-walled carbon nanotubes (Ga(III)-imprinted/CNTs) sorbent was characterized by Fourier transform infrared (FT-IR), X-ray diffraction (XRD), nitrogen adsorption experiment, static adsorption experiment, and solid-phase extraction (SPE) experiment.	Nitrogen	171-179	l(2)46Cc	Drosophila melanogaster	4-11
20490541-6	2010	Activities of key enzymes in nitrogen assimilation and amino acid synthesis, including nitrate reductase, glutamine synthetase, ferredoxin and NADH-dependent glutamate synthase, and glutamate pyruvate transaminase were significantly lower in chlorotic leaves than in normal leaves.	Nitrogen	29-37	ferredoxin C 1, chloroplastic	Malus domestica	128-138
20188224-0	2010	Development and application of mass spectrometric methods for the analysis of progranulin N-glycosylation.	Nitrogen	90-91	granulin precursor	Homo sapiens	78-89
20573193-1	2010	BACKGROUND: The TolC protein from Sinorhizobium meliloti has previously been demonstrated to be required for establishing successful biological nitrogen fixation symbiosis with Medicago sativa.	Nitrogen	144-152	TolC family outer membrane protein	Sinorhizobium meliloti 1021	16-20
20573193-11	2010	Absence of functional TolC caused decreased expression mainly of genes encoding products involved in nitrogen metabolism and transport.	Nitrogen	101-109	TolC family outer membrane protein	Sinorhizobium meliloti 1021	22-26
20188224-3	2010	PGRN is a glycoprotein, containing five N-glycosylation consensus sequons, three of which fall within granulin domains.	Nitrogen	3-4	granulin precursor	Homo sapiens	102-110
20384313-8	2010	Nitrogen-15 enrichment resulted in splitting of the (19)F resonance of fac-OsO(3)F(2)((15)NCCH(3)) into a doublet ((2)J((15)N-(19)F), 21 Hz).	Nitrogen	0-8	FA complementation group C	Homo sapiens	71-74
20368337-10	2010	Together, these studies strongly suggest that N-linked glycosylation of PAR1 at the N terminus versus the surface of ECL2 serves distinct functions critical for proper regulation of receptor trafficking and the fidelity of thrombin signaling.	Nitrogen	46-47	coagulation factor II	Mus musculus	223-231
20446716-8	2010	Pb(II) in 1 is eight-coordinate, with relatively short Pb-N bonds to the two BIM ligands ranging from 2.366(5) to 2.665(5) A, while the four Pb-O bonds are very long at 2.826(5) to 3.123(5) A.	Nitrogen	58-59	submaxillary gland androgen regulated protein 3B	Homo sapiens	0-6
20450227-0	2010	Mutation of putative N-linked glycosylation sites on the human nucleotide receptor P2X7 reveals a key residue important for receptor function.	Nitrogen	21-22	purinergic receptor P2X 7	Homo sapiens	83-87
20450227-7	2010	In further support of a role for glycosylation in receptor function, treatment of RAW 264.7 macrophages with the N-linked glycosylation synthesis inhibitor tunicamycin attenuates P2X(7) agonist-induced, but not phorbol ester-induced, ERK1/2 phosphorylation.	Nitrogen	113-114	purinergic receptor P2X 7	Homo sapiens	179-185
20450227-7	2010	In further support of a role for glycosylation in receptor function, treatment of RAW 264.7 macrophages with the N-linked glycosylation synthesis inhibitor tunicamycin attenuates P2X(7) agonist-induced, but not phorbol ester-induced, ERK1/2 phosphorylation.	Nitrogen	113-114	mitogen-activated protein kinase 3	Homo sapiens	234-240
20335223-5	2010	We identified an N528S homozygous mutation in the VWF propeptide D2 domain, predicting the introduction of an additional N-glycosylation site at amino acid 526 in close vicinity to a "CGLC" disulphide isomerase consensus sequence.	Nitrogen	17-18	von Willebrand factor	Homo sapiens	50-53
24061747-0	2010	Synthesis and Characterization of Co(II) Complexes of N-Thiophosphorylated Thioureas RC(S)NHP(S)(OiPr)2 (R = Me2N, 2-MeC6H4NH, 2,6-Me2C6H3NH, 2,4,6-Me3C6H2NH).	Nitrogen	54-55	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	34-39
21587689-2	2010	The Co(II) atom displays a distorted octa-hedral coordination geometry, provided by the O atoms of two monodentate ferrocene-carboxyl-ate anions and by the N and O atoms of two 2-pyridyl-methanol mol-ecule.	Nitrogen	156-157	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
20394370-12	2010	The porosity of DUT-7 and DUT-7(rac) was proven by nitrogen and hydrogen physisorption measurements.	Nitrogen	51-59	AKT serine/threonine kinase 1	Homo sapiens	26-36
20356820-6	2010	In Arabidopsis ALG3 mutant, an immature lipid-linked oligosaccharide structure, M5(ER), was synthesized, and used for protein N-glycosylation, resulting in the blockade of subsequent maturation with the concanavalin A affinoactive and Endo H-insensitive structure.	Nitrogen	126-127	asparagine-linked glycosylation 3	Arabidopsis thaliana	15-19
20356820-9	2010	These results indicate that AtALG3 is a critical factor for mature N-glycosylation of proteins, but not essential for cell viability and growth in Arabidopsis.	Nitrogen	67-68	asparagine-linked glycosylation 3	Arabidopsis thaliana	28-34
20358221-5	2010	Experiments using PP2A inhibitors, together with PP2Ac expression profiles under conditions that affect tuberization indicate that high sucrose/nitrogen ratio, which promotes tuber formation, increases the transcript levels of Patatin and Pin2, by increasing the activity of PP2As without affecting PP2Ac mRNA or protein levels.	Nitrogen	144-152	Patatin class I	Solanum tuberosum	227-234
20609189-5	2010	The apo A-IV level was positively associated with urea nitrogen and creatinine, and negatively associated with age, interleukin-6, the neutrophil/lymphocyte ratio, and maximum CIMT.	Nitrogen	55-63	apolipoprotein A4	Homo sapiens	4-12
20405064-3	2010	Unusual selectivity for O(2) over N(2) (as high as 6.5) was demonstrated in the materials with open Co(ii) sites.	Nitrogen	34-38	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	100-106
20583713-8	2010	In contrast, the old-growth montane forest located on an Andisol, with low base saturation and aboveground net primary production limited by N, reacted to first-year N addition with increases in gross rates of mineral-N production, microbial biomass, NO3- leaching, and N-oxide emissions compared to the control.	Nitrogen	166-167	NBL1, DAN family BMP antagonist	Homo sapiens	251-254
20494175-10	2010	Concentrations of milk urea nitrogen increased when SC was included in the diet with DDGS.	Nitrogen	28-36	Weaning weight-maternal milk	Bos taurus	18-22
20307605-2	2010	GF-4 inhibited N/OFQ binding to CHO(hNOP) cell membranes (pK(i) 7.46), and antagonized N/OFQ effects in a calcium mobilization assay and electrically stimulated isolated tissues (pK(B) 7.27-7.82), showing a approximately 5-fold selectivity over classical opioid receptors.	Nitrogen	15-16	gonadal fat pad weight 4	Mus musculus	0-4
20307605-2	2010	GF-4 inhibited N/OFQ binding to CHO(hNOP) cell membranes (pK(i) 7.46), and antagonized N/OFQ effects in a calcium mobilization assay and electrically stimulated isolated tissues (pK(B) 7.27-7.82), showing a approximately 5-fold selectivity over classical opioid receptors.	Nitrogen	37-38	gonadal fat pad weight 4	Mus musculus	0-4
20138484-6	2010	We found that expression levels of HSP and Bcl-2 in fibroblasts were strongly dependent on the surface hydrophilicity and concentration of nitrogen-containing functional groups on the nanofiber matrices.	Nitrogen	139-147	BCL2 apoptosis regulator	Homo sapiens	43-48
20471941-2	2010	In yeast, nitrogen and/or carbon limitation causes downregulation of the conserved TORC1 and PKA signaling pathways and, consequently, activation of the PAS kinase Rim15, which orchestrates G(0) program initiation and ensures proper life span by controlling distal readouts, including the expression of specific genes.	Nitrogen	10-18	protein kinase RIM15	Saccharomyces cerevisiae S288C	164-169
20141500-9	2010	CONCLUSION: TNF-alpha in rats caused an acute up-regulation of the in vivo capacity of urea synthesis which may promote loss of nitrogen from the body and catabolism.	Nitrogen	128-136	tumor necrosis factor	Rattus norvegicus	12-21
20202167-8	2010	In Arabidopsis thaliana, over-expression of PPDK during senescence can significantly accelerate nitrogen remobilization from leaves, and thereby increase rosette growth rate and the weight and nitrogen content of seeds.	Nitrogen	96-104	pyruvate orthophosphate dikinase	Arabidopsis thaliana	44-48
20202167-8	2010	In Arabidopsis thaliana, over-expression of PPDK during senescence can significantly accelerate nitrogen remobilization from leaves, and thereby increase rosette growth rate and the weight and nitrogen content of seeds.	Nitrogen	193-201	pyruvate orthophosphate dikinase	Arabidopsis thaliana	44-48
20202167-10	2010	Given that increased seed size and nitrogen content are desirable agronomic traits, and that efficient remobilization of nitrogen within the plant reduces the demand for fertiliser applications, PPDK and the pathway in which it operates are targets for crop improvement.	Nitrogen	121-129	pyruvate orthophosphate dikinase	Arabidopsis thaliana	195-199
20381668-9	2010	Beta-Blocker use, body mass index, and blood urea nitrogen were significant determinants of adiponectin level on multivariate analysis.	Nitrogen	50-58	adiponectin, C1Q and collagen domain containing	Homo sapiens	92-103
20219466-0	2010	Two active and differently N-glycosylated isoforms of human ST3Gal-V are produced from the placental mRNA variant by a leaky scanning mechanism.	Nitrogen	27-28	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Homo sapiens	60-68
19885922-2	2010	For both pSer-Pro and pThr-Pro peptides in the gas phase and in chloroform, the most preferred conformation has the alpha-helical structure for the pSer/pThr residue, the down-puckered polyproline I structure for the Pro residue, and the cis prolyl peptide bond between the two residues, in which two hydrogen bonds between the phosphate oxygens with the backbone N--H groups seem to play a role.	Nitrogen	364-365	parathyroid hormone 1 receptor	Homo sapiens	22-26
20013338-1	2010	Although the fission yeast Schizosaccharomyces pombe has been used for high-level heterologous protein production, the productivity of secreted human serum transferrin (hTF) has been low, presumably, because the protein harbors twenty disulfide bonds and two N-glycosylation sites.	Nitrogen	259-260	transferrin	Homo sapiens	156-167
20005867-4	2010	This feature was associated with increased expression and altered N-linked glycosylation of ATP binding cassette transporters MRP1 and MRP4.	Nitrogen	66-67	ATP binding cassette subfamily C member 1	Homo sapiens	126-130
20207143-0	2010	Synthesis and biological evaluation of nitrogen-containing benzophenone analogues as TNF-alpha and IL-6 inhibitors with antioxidant activity.	Nitrogen	39-47	tumor necrosis factor	Homo sapiens	85-94
20207143-0	2010	Synthesis and biological evaluation of nitrogen-containing benzophenone analogues as TNF-alpha and IL-6 inhibitors with antioxidant activity.	Nitrogen	39-47	interleukin 6	Homo sapiens	99-103
20207143-1	2010	A series of nitrogen-containing benzophenone analogues were synthesized by Mannich reaction and evaluated for the inhibition of pro-inflammatory cytokines, TNF-alpha and IL-6.	Nitrogen	12-20	tumor necrosis factor	Homo sapiens	156-165
20207143-1	2010	A series of nitrogen-containing benzophenone analogues were synthesized by Mannich reaction and evaluated for the inhibition of pro-inflammatory cytokines, TNF-alpha and IL-6.	Nitrogen	12-20	interleukin 6	Homo sapiens	170-174
19885922-2	2010	For both pSer-Pro and pThr-Pro peptides in the gas phase and in chloroform, the most preferred conformation has the alpha-helical structure for the pSer/pThr residue, the down-puckered polyproline I structure for the Pro residue, and the cis prolyl peptide bond between the two residues, in which two hydrogen bonds between the phosphate oxygens with the backbone N--H groups seem to play a role.	Nitrogen	364-365	parathyroid hormone 1 receptor	Homo sapiens	153-157
20641863-0	2004	(99m)Tc-Labeled N(epsilon49) mercaptoacetyl derivatives of affibody ZHER2:342 targeting the human epidermal growth factor receptor Overexpression of the epidermal growth factor receptor type 2 (HER2) is a characteristic feature of a variety of cancers, and HER2 levels in tumors (primary or metastatic) are often used to screen for patients who would benefit from anti-HER2 antibody (Ab) therapy (e.g., for breast cancer, etc.	Nitrogen	16-17	erb-b2 receptor tyrosine kinase 2	Homo sapiens	69-73
20397810-9	2010	IS-SCGB1A1/IL8 levels were also inversely associated with nitrogen slope [r = -0.52, p &lt; 0.001] and HRCT SA score [r = -0.51, p &lt; 0.001].	Nitrogen	58-66	C-X-C motif chemokine ligand 8	Homo sapiens	11-14
20186149-6	2010	The elevation of serum creatinine and urea nitrogen levels at 18 weeks of diabetes was more prominent in ACE2-KO mice.	Nitrogen	43-51	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	105-109
20154096-1	2010	The chloroplastic NAD kinase (NADK2) is reported to stimulate carbon and nitrogen assimilation in Arabidopsis (Arabidopsis thaliana), which is vulnerable to high light.	Nitrogen	73-81	NAD kinase 2	Arabidopsis thaliana	30-35
20184343-1	2010	A highly effective Co(II)-based system has been developed for catalytic intramolecular C-H amination with phosphoryl azides without the need of terminal oxidant or other additives, resulting in the high-yielding production of cyclophosphoramidates with nitrogen gas as the byproduct.	Nitrogen	253-261	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	19-24
20447077-2	2010	EGFR is a glycoprotein with 12 potential N-glycosylation sites in its extracellular domain.	Nitrogen	41-42	epidermal growth factor receptor	Homo sapiens	0-4
20034524-10	2010	PACAP was renoprotective in vivo and prevented the rise in blood urea nitrogen and creatinine in mice treated with cisplatin.	Nitrogen	70-78	adenylate cyclase activating polypeptide 1	Mus musculus	0-5
20189213-5	2010	Biomass in strongly nitrogen-limited SBRs had higher baseline PHA contents in the SBR, but carbon-limited SBRs resulted usually in biomass with higher maximal PHA storage capacities.	Nitrogen	20-28	lamin B receptor	Homo sapiens	62-65
20189213-6	2010	The PHA storage capacity in a nitrogen-limited SBR operated at 0.5 d SRT decreased significantly over less than 5 months operation.	Nitrogen	30-38	lamin B receptor	Homo sapiens	4-7
20641863-0	2004	(99m)Tc-Labeled N(epsilon49) mercaptoacetyl derivatives of affibody ZHER2:342 targeting the human epidermal growth factor receptor Overexpression of the epidermal growth factor receptor type 2 (HER2) is a characteristic feature of a variety of cancers, and HER2 levels in tumors (primary or metastatic) are often used to screen for patients who would benefit from anti-HER2 antibody (Ab) therapy (e.g., for breast cancer, etc.	Nitrogen	16-17	erb-b2 receptor tyrosine kinase 2	Homo sapiens	194-198
20641863-0	2004	(99m)Tc-Labeled N(epsilon49) mercaptoacetyl derivatives of affibody ZHER2:342 targeting the human epidermal growth factor receptor Overexpression of the epidermal growth factor receptor type 2 (HER2) is a characteristic feature of a variety of cancers, and HER2 levels in tumors (primary or metastatic) are often used to screen for patients who would benefit from anti-HER2 antibody (Ab) therapy (e.g., for breast cancer, etc.	Nitrogen	16-17	erb-b2 receptor tyrosine kinase 2	Homo sapiens	194-198
20146449-8	2010	High-resolution DESI-MS analysis demonstrated that chemical aging results in formation of highly conjugated nitrogen-containing species that are most likely responsible for light-absorbing properties of the aged LSOA.	Nitrogen	108-116	desumoylating isopeptidase 2	Homo sapiens	16-20
19861159-12	2010	Three major mechanisms are discussed to be involved in enhancing the PHD activity despite the lack of oxygen: (1) NO mediated induction of a HIF-1 dependent feedback loop leading to newly expressed PHD2 and enhanced nuclear localization, (2) O2-redistribution towards PHDs after inhibition of mitochondrial respiration by NO, (3) reactivation of PHD activity by a NO mediated increase of iron and 2-oxoglutarate and/or involvement of reactive oxygen and/or nitrogen species.	Nitrogen	457-465	hypoxia inducible factor 1 subunit alpha	Homo sapiens	141-146
19909758-3	2010	The major pathway of its repair is initiated by uracil-DNA glycosylases (UNG), ubiquitously found enzymes that hydrolyze the N-glycosidic bond of deoxyuridine in DNA.	Nitrogen	56-57	uracil DNA glycosylase	Homo sapiens	73-76
19958834-0	2010	The resolution dependence of optimal exposures in liquid nitrogen temperature electron cryomicroscopy of catalase crystals.	Nitrogen	57-65	catalase	Homo sapiens	105-113
19333721-8	2010	The expression of alcohol dehydrogenase increased remarkably by nitrogen substitution compared to flooding.	Nitrogen	64-72	alcohol dehydrogenase	Glycine max	18-39
20370696-1	2010	In addition to being responsible for the majority of absorption of dietary nitrogen, the mammalian proton-coupled di- and tri-peptide transporter PepT1 is also recognised as a major route of drug delivery for several important classes of compound, including beta-lactam antibiotics and angiotensin-converting enzyme inhibitors.	Nitrogen	75-83	solute carrier family 15 member 1	Homo sapiens	146-151
19880629-8	2010	These findings provide evidence that the Hcy-thiolactonase activity of PON1 is a determinant of plasma N-Hcy-protein levels and that Hcy-thiolactonase/PON1 protects proteins against N-homocysteinylation in vivo, a novel mechanism likely to contribute to atheroprotective roles of HDL in humans.-Perla-Kajan, J., Jakubowski, H. Paraoxonase 1 protects against protein N-homocysteinylation in humans.	Nitrogen	73-74	paraoxonase 1	Homo sapiens	151-155
19880629-8	2010	These findings provide evidence that the Hcy-thiolactonase activity of PON1 is a determinant of plasma N-Hcy-protein levels and that Hcy-thiolactonase/PON1 protects proteins against N-homocysteinylation in vivo, a novel mechanism likely to contribute to atheroprotective roles of HDL in humans.-Perla-Kajan, J., Jakubowski, H. Paraoxonase 1 protects against protein N-homocysteinylation in humans.	Nitrogen	73-74	paraoxonase 1	Homo sapiens	327-340
19931606-5	2010	Nitrogen sorption analysis showed that the specific surface area and pore volume decreased according to the insulin adsorption.	Nitrogen	0-8	insulin	Homo sapiens	108-115
20045315-7	2010	An additional hydrogen bond interaction of the piperidine nitrogen to Gly-888 also contributes to the binding affinity of 1e to PARP-1.	Nitrogen	58-66	poly(ADP-ribose) polymerase 1	Homo sapiens	128-134
19636575-7	2010	Antibodies recognizing highly N-sulfated HS demonstrated the highest level of staining in both fibrillar Abeta plaques and non-fibrillar Abeta plaques, whereas antibodies recognizing HS regions with a lower degree of N-sulfate modifications were only immunoreactive with fibrillar Abeta plaques.	Nitrogen	30-31	amyloid beta precursor protein	Homo sapiens	105-110
19636575-7	2010	Antibodies recognizing highly N-sulfated HS demonstrated the highest level of staining in both fibrillar Abeta plaques and non-fibrillar Abeta plaques, whereas antibodies recognizing HS regions with a lower degree of N-sulfate modifications were only immunoreactive with fibrillar Abeta plaques.	Nitrogen	30-31	amyloid beta precursor protein	Homo sapiens	137-142
19636575-7	2010	Antibodies recognizing highly N-sulfated HS demonstrated the highest level of staining in both fibrillar Abeta plaques and non-fibrillar Abeta plaques, whereas antibodies recognizing HS regions with a lower degree of N-sulfate modifications were only immunoreactive with fibrillar Abeta plaques.	Nitrogen	30-31	amyloid beta precursor protein	Homo sapiens	137-142
19782129-5	2010	Tunicamycin prevented the N-linked glycosylation and maturation of PDGFRbeta as well as its activation by PDGF-BB.	Nitrogen	26-27	platelet derived growth factor receptor beta	Homo sapiens	67-76
19846580-10	2010	When the N-linked asialo-agalacto-biantennary glycan acceptor was utilized with GnT-Vb, the expected triantennary beta1,6-branched product was observed up to 8 h incubation.	Nitrogen	9-10	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	80-86
20030721-1	2010	We demonstrated that a yeast deletion mutant in IPT1 and SKN1, encoding proteins involved in the biosynthesis of mannosyldiinositolphosphoryl ceramides, is characterized by increased autophagy and DNA fragmentation upon nitrogen (N) starvation as compared with the single deletion mutants or wild type (WT).	Nitrogen	220-228	inositolphosphotransferase	Saccharomyces cerevisiae S288C	48-52
19807146-0	2010	Dynamics of formation of products D2CN+, DCN+, and CD3+ in the reaction of N+ with CD4: a crossed-beam and theoretical study.	Nitrogen	37-39	CD4 molecule	Homo sapiens	83-86
19937756-7	2010	Mechanistically, N-sulfation was identified to be critical for functional autocrine fibroblast growth factor 4 (FGF4) signaling.	Nitrogen	17-18	fibroblast growth factor 4	Homo sapiens	84-110
19937756-7	2010	Mechanistically, N-sulfation was identified to be critical for functional autocrine fibroblast growth factor 4 (FGF4) signaling.	Nitrogen	17-18	fibroblast growth factor 4	Homo sapiens	112-116
19807146-1	2010	The formation of D(2)CN(+) in the reaction of N(+) ((3)P) with CD(4) was studied using the crossed beam technique at collision energies of 3.66 and 4.86 eV.	Nitrogen	22-26	CD4 molecule	Homo sapiens	63-68
20336500-4	2010	The two recombinant strains grown on a mineral medium with 1 % chicken feather as source of energy, carbon and nitrogen exhibited higher proteolytic activity ( approximately 6-fold and 2.4-fold higher for strains 23/1 (p5.2) and 6/2 (p5.2), respectively.	Nitrogen	111-119	protein kinase C and casein kinase substrate in neurons 2	Gallus gallus	219-223
20005707-1	2010	A novel series of nitrogen-containing chalcones were synthesized by Mannich reaction and were screened for anti-inflammatory related activities such as inhibition of cyclooxygenase-2 (COX-2), trypsin and beta-glucuronidase.	Nitrogen	18-26	prostaglandin-endoperoxide synthase 2	Homo sapiens	166-182
20005707-1	2010	A novel series of nitrogen-containing chalcones were synthesized by Mannich reaction and were screened for anti-inflammatory related activities such as inhibition of cyclooxygenase-2 (COX-2), trypsin and beta-glucuronidase.	Nitrogen	18-26	prostaglandin-endoperoxide synthase 2	Homo sapiens	184-189
20006580-1	2010	Within the first external loop of mouse and human TRESK subunits one or two N-glycosylation consensus sites were identified, respectively.	Nitrogen	76-77	potassium two pore domain channel subfamily K member 18	Homo sapiens	50-55
20008137-5	2010	In addition, IL-6-deficient (IL-6(-/-)) mice exhibited exaggerated histopathological changes with higher blood urea nitrogen and creatinine levels.	Nitrogen	116-124	interleukin 6	Mus musculus	13-17
20008137-5	2010	In addition, IL-6-deficient (IL-6(-/-)) mice exhibited exaggerated histopathological changes with higher blood urea nitrogen and creatinine levels.	Nitrogen	116-124	interleukin 6	Mus musculus	29-33
19947643-5	2010	There are two ways in which the undissociated form of a bis-chelated complex can interact with transferrin, one "specific" when the carrier possesses a carboxylate group and behaves like a synergistic anion, and another "non-specific" when an imidazole nitrogen of a histidine residue from hTf replaces an equatorially coordinated water molecule giving rise to a ternary species with cis-octahedral geometry and cis-VO(carrier)(2)(hTf) stoichiometry.	Nitrogen	253-261	transferrin	Homo sapiens	95-106
19800422-1	2010	Matriptase is a type II transmembrane serine protease containing one potential site for asparagine-linked glycosylation (N-glycosylation) on the catalytic domain (Asn772).	Nitrogen	121-122	ST14 transmembrane serine protease matriptase	Rattus norvegicus	0-10
19800422-2	2010	It has been found that the activation of matriptase zymogen occurs via a mechanism requiring its own activity and that the N-glycosylation site is critical for the activation.	Nitrogen	123-124	ST14 transmembrane serine protease matriptase	Rattus norvegicus	41-51
19800422-6	2010	It is concluded that N-glycosylation site at Asn772 of matriptase is required for the zymogen activation because it plays an important role in rendering this protease catalytically competent in the cellular environment.	Nitrogen	21-22	ST14 transmembrane serine protease matriptase	Rattus norvegicus	55-65
20336500-4	2010	The two recombinant strains grown on a mineral medium with 1 % chicken feather as source of energy, carbon and nitrogen exhibited higher proteolytic activity ( approximately 6-fold and 2.4-fold higher for strains 23/1 (p5.2) and 6/2 (p5.2), respectively.	Nitrogen	111-119	protein kinase C and casein kinase substrate in neurons 2	Gallus gallus	234-238
19551866-0	2010	N-glycosylation status of beta-haptoglobin in sera of patients with colon cancer, chronic inflammatory diseases and normal subjects.	Nitrogen	0-1	haptoglobin	Homo sapiens	31-42
19569175-3	2010	In this study, we investigated the potential molecular mechanisms underlying the antiangiogenic effect of non-nitrogen-containing and nitrogen-containing bisphosphonates, clodronate and pamidronate, respectively, in insulin-like growth factor (IGF)-1 responsive human breast cancer cells.	Nitrogen	134-142	insulin like growth factor 1	Homo sapiens	216-250
20628587-5	2010	In particular, both particles induced up-regulation of iNOS expression in Big Blue, suggesting the formation of potentially genotoxic nitrogen species.	Nitrogen	134-142	nitric oxide synthase 2	Rattus norvegicus	55-59
20397415-4	2010	The results showed that nitrate reduction rate improved as H2 pressure increasing, and over 97% of total nitrogen removal rate was achieved when the nitrate loading increased from 0.17 to 0.34 g NO3- -N/(m2 x day) without nitrite accumulation.	Nitrogen	105-113	NBL1, DAN family BMP antagonist	Homo sapiens	195-198
20798757-1	2010	This study explored if a combined supplementation of GH and IGF-1 had an additive effect on whole body nitrogen economy, energy, substrate and skeletal muscle metabolism following surgical trauma.	Nitrogen	103-111	insulin like growth factor 1	Homo sapiens	60-65
19858196-8	2010	Kinetic results suggest that GDH1 facilitates regeneration of the form of BCATm that binds to E1 decarboxylase of the BCKDC, promotes metabolon formation, branched-chain amino acid oxidation, and cycling of nitrogen through glutamate.	Nitrogen	207-215	branched chain amino acid transaminase 2	Homo sapiens	74-79
20419423-5	2010	We use a combination of siRNA-mediated knockdown of individual proteins combined with a semi-permeabilized mammalian cell system to provide a robust read out for OST subunit function during N-glycosylation of model substrates in vitro.	Nitrogen	27-28	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	162-165
20085895-7	2010	Furthermore, the metabolomic and transcriptomic analysis of the Os-LBD37/ASL39-overexpressing rice plants indicated that Os-LBD37/ASL39 is associated with processes related to nitrogen metabolism in rice.	Nitrogen	176-184	LOB domain-containing protein 37	Arabidopsis thaliana	73-78
20085895-7	2010	Furthermore, the metabolomic and transcriptomic analysis of the Os-LBD37/ASL39-overexpressing rice plants indicated that Os-LBD37/ASL39 is associated with processes related to nitrogen metabolism in rice.	Nitrogen	176-184	LOB domain-containing protein 37	Arabidopsis thaliana	130-135
19632034-5	2009	The presence of externally added inorganic electron acceptors like NO2(-), NO3(-) and SO4(2-) was effective in anoxic ammonia oxidation, but failed to follow the reported anammox reaction"s stoichiometry in nitrogen removal in the presence of organic carbon.	Nitrogen	207-215	NBL1, DAN family BMP antagonist	Homo sapiens	75-78
20509569-8	2010	RESULTS: Before starting enteral nutrition, we found increased VEGF concentration in CD group (Me = 600 pg/ml) compared to UC group (266.9 pg/ml), AP group (552.6 pg/ml), N group (238.5 pg/ml) and controls (172 pg/ml) (p &lt; 0.05).	Nitrogen	171-172	vascular endothelial growth factor A	Homo sapiens	63-67
19880517-2	2009	TDG cleaves the N-glycosylic bond of dT and some other nucleotides, including 5-substituted 2"-deoxyuridine analogs, once they have been flipped from the helix into its active site.	Nitrogen	16-17	thymine DNA glycosylase	Homo sapiens	0-3
19914323-2	2010	Inflammatory stimuli upregulate transcription of inducible nitric oxide synthase (iNOS), which can lead to the production of nitric oxide and other reactive nitrogen species.	Nitrogen	157-165	nitric oxide synthase 2, inducible	Mus musculus	49-80
19914323-2	2010	Inflammatory stimuli upregulate transcription of inducible nitric oxide synthase (iNOS), which can lead to the production of nitric oxide and other reactive nitrogen species.	Nitrogen	157-165	nitric oxide synthase 2, inducible	Mus musculus	82-86
19860378-2	2009	Moreover, we have shown that the absence of a nitrogen atom in the spacer of the helicand ligand H(2)L(a), enables the assembly of an achiral mesohelical complex in the case of Co(II) ions.	Nitrogen	46-54	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	177-183
19808082-2	2009	As one of pathogenic components of diabetes angiotensin II (Ang II) induced cardiac cell death in vitro and in vivo through induction of reactive oxygen and nitrogen species.	Nitrogen	157-165	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	44-58
19808082-2	2009	As one of pathogenic components of diabetes angiotensin II (Ang II) induced cardiac cell death in vitro and in vivo through induction of reactive oxygen and nitrogen species.	Nitrogen	157-165	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Mus musculus	60-66
19909340-0	2009	Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2.	Nitrogen	14-15	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	135-140
19615464-5	2009	In addition, HRASLS2 catalyzed N-acylation of PE to form N-acyl-PE and O-acylation of lyso PC to form PC.	Nitrogen	31-32	phospholipase A and acyltransferase 2	Homo sapiens	13-20
20187385-8	2009	The NO3- -delta 15N values of 4.77% per hundred (n=9) show nitrate-nitrogen of S2 mainly originates from fertilizers from October, 2007 to March, 2008 and from July to October, 2008, while NO3- -delta 15N values of 3.16% per hundred +/- 0.39% per hundred (n=5) explain that the nitrate-nitrogen derives from the mixture of soil organic nitrogen and fertilizers from April to June, 2008.	Nitrogen	67-75	NBL1, DAN family BMP antagonist	Homo sapiens	4-7
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	0-2	CD59 molecule (CD59 blood group)	Homo sapiens	253-259
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	177-183
20187399-3	2009	N2 stripping was used to remove H2S produced in the reactor, and the average diameter of granular sludge increased to 1.51 mm quickly when N2 stripping with the flux of 60 mL x min(-1) was used, but it decreased when the flux of N2 improved to 100 mL x min(-1).	Nitrogen	139-141	CD59 molecule (CD59 blood group)	Homo sapiens	253-259
19949684-4	2009	Fibrinogen Yecheon has a de novo heterozygous point mutation of FGG resulting in gamma Met310Thr and subsequent extra N-glycosylation at gamma Asn308.	Nitrogen	118-119	fibrinogen beta chain	Homo sapiens	0-10
19949684-4	2009	Fibrinogen Yecheon has a de novo heterozygous point mutation of FGG resulting in gamma Met310Thr and subsequent extra N-glycosylation at gamma Asn308.	Nitrogen	118-119	fibrinogen gamma chain	Homo sapiens	64-67
19949684-5	2009	Extra N-glycosylated fibrinogen is considered a main inhibitor of normal fibrinogen activity.	Nitrogen	6-7	fibrinogen beta chain	Homo sapiens	21-31
19949684-5	2009	Extra N-glycosylated fibrinogen is considered a main inhibitor of normal fibrinogen activity.	Nitrogen	6-7	fibrinogen beta chain	Homo sapiens	73-83
19909340-5	2009	When ABCG2 wild type-expressing cells were incubated with various N-linked glycosylation inhibitors, tunicamycin profoundly suppressed the protein expression level of ABCG2 and, accordingly, reduced the ABCG2-mediated cellular resistance to the cancer chemotherapeutic SN-38.	Nitrogen	66-67	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	5-10
19909340-5	2009	When ABCG2 wild type-expressing cells were incubated with various N-linked glycosylation inhibitors, tunicamycin profoundly suppressed the protein expression level of ABCG2 and, accordingly, reduced the ABCG2-mediated cellular resistance to the cancer chemotherapeutic SN-38.	Nitrogen	66-67	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	167-172
19909340-5	2009	When ABCG2 wild type-expressing cells were incubated with various N-linked glycosylation inhibitors, tunicamycin profoundly suppressed the protein expression level of ABCG2 and, accordingly, reduced the ABCG2-mediated cellular resistance to the cancer chemotherapeutic SN-38.	Nitrogen	66-67	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	167-172
19585521-0	2009	Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.	Nitrogen	75-76	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	30-33
19828671-9	2009	Significant differences were found in the quantity of total grain nitrogen allocated to the gliadin protein fractions for the Spa-A haplotypes, whereas the synthesis of glutenins is not modified.	Nitrogen	66-74	bZIP transcription factor RISBZ2	Triticum aestivum	126-129
19333145-4	2009	Levels of TNF-alpha were significantly expressed 1 h after LPS administration, followed by 1) an increase in levels of tissue factor, factor VIIa, factor Xa, thrombin and plasminogen activator inhibitor 1; 2) unchanged levels of tissue factor pathway inhibitor; and 3) subsequent deposition of fibrin in kidney tissues, which led to the elevation of creatinine and blood urea nitrogen.	Nitrogen	376-384	tumor necrosis factor	Rattus norvegicus	10-19
19930605-3	2009	With the combination of 2-DE and western blot techniques and the aid of tunicamycin, we analyzed N-glycosylation variants of VCAM-1 in primary human endothelial cells stimulated with either TNF or tumoral soluble factors (TSF"s) derived from the human breast cancer cell line ZR75.30.	Nitrogen	97-98	vascular cell adhesion molecule 1	Homo sapiens	125-131
19780566-2	2009	The crystal structure determinations of 1 and 2 reveal in both cases discrete iron(II) monomeric structures in which the two functionalized tetraazamacrocycles (L1 and L2) act as hexadentate ligands; the iron(II) ions are coordinated with six nitrogen atoms: four from the macrocycle and two from two pyridine groups occupying two cis positions around the metal ion.	Nitrogen	243-251	L1 cell adhesion molecule	Homo sapiens	161-170
19903955-5	2009	The increases observed in TTAR of nitrogen and ether extract and on AME(n) of the diet were more pronounced with OH than with SBP.	Nitrogen	34-42	sucrose-binding protein 2	Glycine max	126-129
19815554-7	2009	Thus, our results describe N-myristoylation as a regulative mechanism of FMNL1 responsible for membrane trafficking potentially involved in a diversity of polarized processes of hematopoietic lineage-derived cells.	Nitrogen	27-28	formin like 1	Homo sapiens	73-78
19833167-5	2009	A correlation between increase in serum IL-6 level and blood urea nitrogen level was found in WT mice.	Nitrogen	66-74	interleukin 6	Mus musculus	40-44
19901341-5	2009	Moreover, Dot6 and Tod6 mediate different nutrient signals, with Tod6 responsible for efficient repression of Ribi genes after inhibition of the nitrogen-sensitive TORC1 pathway and Dot6 responsible for repression after inhibition of the carbon-sensitive protein kinase A signaling pathway.	Nitrogen	145-153	Dot6p	Saccharomyces cerevisiae S288C	10-14
19901341-5	2009	Moreover, Dot6 and Tod6 mediate different nutrient signals, with Tod6 responsible for efficient repression of Ribi genes after inhibition of the nitrogen-sensitive TORC1 pathway and Dot6 responsible for repression after inhibition of the carbon-sensitive protein kinase A signaling pathway.	Nitrogen	145-153	Dot6p	Saccharomyces cerevisiae S288C	182-186
19389486-1	2009	The mammalian proton-coupled peptide transporter PepT1 is widely accepted as the major route of uptake for dietary nitrogen, as well as being responsible for the oral absorption of a number of classes of drugs, including beta-lactam antibiotics and angiotensin-converting enzyme (ACE) inhibitors.	Nitrogen	115-123	solute carrier family 15 member 1	Homo sapiens	49-54
19389486-1	2009	The mammalian proton-coupled peptide transporter PepT1 is widely accepted as the major route of uptake for dietary nitrogen, as well as being responsible for the oral absorption of a number of classes of drugs, including beta-lactam antibiotics and angiotensin-converting enzyme (ACE) inhibitors.	Nitrogen	115-123	angiotensin I converting enzyme	Homo sapiens	249-278
19389486-1	2009	The mammalian proton-coupled peptide transporter PepT1 is widely accepted as the major route of uptake for dietary nitrogen, as well as being responsible for the oral absorption of a number of classes of drugs, including beta-lactam antibiotics and angiotensin-converting enzyme (ACE) inhibitors.	Nitrogen	115-123	angiotensin I converting enzyme	Homo sapiens	280-283
19933203-7	2009	The LBD genes also repress many other known N-responsive genes, including key genes required for NO(3)(-) uptake and assimilation, resulting in altered NO(3)(-) content, nitrate reductase activity/activation, protein, amino acid, and starch levels, and N-related growth phenotypes.	Nitrogen	44-45	nitrate reductase 1	Arabidopsis thaliana	170-187
19933203-8	2009	The results identify LBD37 and its two close homologs as novel repressors of anthocyanin biosynthesis and N availability signals in general.	Nitrogen	106-107	LOB domain-containing protein 37	Arabidopsis thaliana	21-26
19875801-7	2009	When flume water was spiked with NH4-N and NO3-N to simulate increases in N concentrations from drainage and runoff from adjacent fields, NO3-N in flume water increased during 48 h compared with the initial spiked concentration, while NH4-N decreased.	Nitrogen	33-34	NBL1, DAN family BMP antagonist	Homo sapiens	138-141
20081260-4	2009	A comparative in vitro study provides clear evidence that ticlopidine and DDC, applied at concentrations that inhibit the above-mentioned CYP isoforms, potently (as compared to furafylline) inhibit human CYP1A2 and caffeine metabolism, in particular 1-N- and 3-N-demethylation.	Nitrogen	252-253	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	138-141
19875801-9	2009	Replacing the N-spiked water with deionized water resulted in two times more NO3-N released from the undredged ditch sediment than the dredged ditch sediment.	Nitrogen	14-15	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
19464754-0	2009	Inhibition of nitrogen-fixing activity of the cyanobiont affects the localization of glutamine synthetase in hair cells of Azolla.	Nitrogen	14-22	glutamate-ammonia ligase	Homo sapiens	85-105
19464754-1	2009	In the Azolla-Anabaena association, the host plant Azolla efficiently incorporates and assimilates ammonium ions that are released from the nitrogen-fixing cyanobiont, probably via glutamine synthetase (GS; EC 6.3.1.2) in hair cells, which are specialized cells protruding into the leaf cavity.	Nitrogen	140-148	glutamate-ammonia ligase	Homo sapiens	181-201
19464754-1	2009	In the Azolla-Anabaena association, the host plant Azolla efficiently incorporates and assimilates ammonium ions that are released from the nitrogen-fixing cyanobiont, probably via glutamine synthetase (GS; EC 6.3.1.2) in hair cells, which are specialized cells protruding into the leaf cavity.	Nitrogen	140-148	glutamate-ammonia ligase	Homo sapiens	203-205
19711901-0	2009	Nitrogen-atom transfer from [PW11O39Ru(VI)N]4- to PPh3.	Nitrogen	0-8	caveolin 1	Homo sapiens	50-54
19557310-2	2009	By maintaining the pH in the cathode at 7.2, nitrogen removal was increased from 0.22 to 0.50 kg NO(3) (-)-Nm(-3) NCC d(-1).	Nitrogen	45-53	NBL1, DAN family BMP antagonist	Homo sapiens	97-102
19539407-6	2009	Molecular modelling indicated an important interaction between the oxazoline nitrogen and FAAH active site.	Nitrogen	77-85	fatty acid amide hydrolase	Homo sapiens	90-94
19640904-4	2009	In a murine model, pretreating wild-type (WT) mice with a PPAR-alpha activator, docosahexaenoic acid (DHA), significantly reduced I/R-induced renal dysfunction (lowered serum creatinine and urea nitrogen levels), apoptotic responses (decreased apoptotic cell number and caspase-3, -8 activation), and NF-kappaB activation.	Nitrogen	195-203	peroxisome proliferator activated receptor alpha	Mus musculus	58-68
19561031-0	2009	Role of N-glycosylation of the SEA module of rodent Muc3 in posttranslational processing of its carboxy-terminal domain.	Nitrogen	8-9	MUC3	Homo sapiens	52-56
19561031-2	2009	There are seven potential N-glycosylation sites that occur in a cluster in the SEA module of Muc3.	Nitrogen	26-27	MUC3	Homo sapiens	93-97
19561031-4	2009	Our data show that the proteolytic cleavage of the rodent Muc3 SEA module was partially prevented by treatment with tunicamycin, an inhibitor of N-glycosylation.	Nitrogen	145-146	MUC3	Homo sapiens	58-62
19700330-3	2009	A structure-affinity relationship (SAFIR) study was carried out studying the effects of N-methylation, varying the linker chain length and constraint of the aromatic rings on the binding affinities of the compounds with the 5-HT(2A) and H(1) receptors.	Nitrogen	88-89	5-hydroxytryptamine receptor 2A	Homo sapiens	226-231
19762829-7	2009	Milk composition was not altered by glycerol feeding except that milk urea nitrogen was decreased from 12.5 +/- 0.4 to 10.2 +/- 0.4 mg/dL with glycerol addition.	Nitrogen	75-83	Weaning weight-maternal milk	Bos taurus	65-69
20502620-0	2009	N-glycosylation status of E-cadherin controls cytoskeletal dynamics through the organization of distinct beta-catenin- and gamma-catenin-containing AJs.	Nitrogen	0-1	cadherin 1	Homo sapiens	26-36
20502620-1	2009	N-glycosylation of E-cadherin has been shown to inhibit cell-cell adhesion.	Nitrogen	0-1	cadherin 1	Homo sapiens	19-29
20502620-2	2009	Specifically, our recent studies have provided evidence that the reduction of E-cadherin N-glycosylation promoted the recruitment of stabilizing components, vinculin and serine/threonine protein phosphatase 2A (PP2A), to adherens junctions (AJs) and enhanced the association of AJs with the actin cytoskeleton.	Nitrogen	89-90	cadherin 1	Homo sapiens	78-88
20502620-3	2009	Here, we examined the details of how N-glycosylation of E-cadherin affected the molecular organization of AJs and their cytoskeletal interactions.	Nitrogen	37-38	cadherin 1	Homo sapiens	56-66
20502620-7	2009	N-glycosylation driven changes in the molecular organization of AJs were physiologically significant because transfection of V13 into A253 cancer cells, lacking both mature AJs and tight junctions (TJs), promoted the formation of stable AJs and enhanced the function of TJs to a greater extent than wild-type E-cadherin.	Nitrogen	0-1	immunoglobulin lambda variable 2-11	Homo sapiens	125-128
20502620-7	2009	N-glycosylation driven changes in the molecular organization of AJs were physiologically significant because transfection of V13 into A253 cancer cells, lacking both mature AJs and tight junctions (TJs), promoted the formation of stable AJs and enhanced the function of TJs to a greater extent than wild-type E-cadherin.	Nitrogen	0-1	cadherin 1	Homo sapiens	309-319
20502620-8	2009	These studies provide the first mechanistic insights into how N-glycosylation of E-cadherin drives changes in AJ composition through the assembly of distinct beta-catenin- and gamma-catenin-containing scaffolds that impact the interaction with different cytoskeletal components.	Nitrogen	62-63	cadherin 1	Homo sapiens	81-91
19574222-2	2009	The transcriptional activator Put3p allows yeast cells to utilize proline as a nitrogen source through expression of the PUT1 and PUT2 genes.	Nitrogen	79-87	proline dehydrogenase	Saccharomyces cerevisiae S288C	121-125
19553348-4	2009	Renal function as assessed by plasma levels of both creatinine and blood urea nitrogen was significantly reduced in CypD knockout (CypD(-/-)) mice compared with wild-type mice during the 5-day post-ischemia period.	Nitrogen	78-86	peptidylprolyl isomerase F (cyclophilin F)	Mus musculus	116-120
19621239-4	2009	Several structural genes of flavonoid metabolism including CHS (chalcone synthase), FLS1 (flavonol synthase 1) and ANS (anthocyanidin synthase) were induced in response to nitrogen depletion in wild type as well as in the egl3 and gl3 mutants.	Nitrogen	172-180	leucoanthocyanidin dioxygenase	Arabidopsis thaliana	120-142
19769131-11	2009	Nitrogen processing efficiency decreased with NO3- load in all pools, suggesting that the nutrient processing capacity of the marsh ecosystem was exceeded in the fertilized marsh.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	46-49
19534677-4	2009	The derived QSAR models demonstrated that the COX-2 selectivity over COX-1 is predominantly influenced by the central core -N=C- of the diaryl system.	Nitrogen	124-125	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	46-51
19737976-6	2009	Inhibition of constitutive Kit TK activity with dasatinib induced a complex, mature N-glycosylation pattern identical to unstimulated wild-type Kit and resulted in the redistribution of the mutants to the plasma membrane.	Nitrogen	84-85	KIT proto-oncogene, receptor tyrosine kinase	Homo sapiens	27-30
19737976-9	2009	Kit mutants are then exported and/or stabilized at the cell surface as inactive and fully N-glycosylated isoforms.	Nitrogen	90-91	KIT proto-oncogene, receptor tyrosine kinase	Homo sapiens	0-3
19171192-3	2009	Based on the iso-electric focusing patterns of plasma transferrin and apolipoprotein C-III a combined defect in N- and O-glycosylation was identified in patients with autosomal recessive cutis laxa type II (ARCL II).	Nitrogen	112-113	transferrin	Homo sapiens	54-65
19587098-0	2009	Pleiotropic modulation of carbon and nitrogen metabolism in Arabidopsis plants overexpressing the NAD kinase2 gene.	Nitrogen	37-45	NAD kinase 2	Arabidopsis thaliana	98-109
19587098-5	2009	Furthermore, enhanced NADP(H) production due to NADK2 overexpression increased nitrogen assimilation.	Nitrogen	79-87	NAD kinase 2	Arabidopsis thaliana	48-53
19587098-7	2009	These results indicate that overexpression of NADK2 either directly or indirectly stimulates carbon and nitrogen assimilation in Arabidopsis under restricted conditions.	Nitrogen	104-112	NAD kinase 2	Arabidopsis thaliana	46-51
19608424-4	2009	The X-ray analysis of [Ni(i-MNT)(2a-5mt)(2)] shows the nickel atom being fourfold coordinated with the two sulfur atoms of the dithiolate (i-MNT) ligand and the endocyclic nitrogen atoms from the two 2a-5mt ring giving rise to a slightly distorted square-planar arrangement.	Nitrogen	172-180	MAX network transcriptional repressor	Bos taurus	28-31
19652279-1	2009	We have performed a detailed investigation of the molecular beam epitaxial growth and characterization of InN nanowires spontaneously formed on Si(111) substrates under nitrogen rich conditions.	Nitrogen	169-177	growth hormone releasing hormone	Homo sapiens	106-109
19412639-1	2009	Genetic mutations frequently observed in human follicular lymphoma (FL) B-cells result in aberrant expression of the anti-apoptotic protein bcl-2 and surface immunoglobulins (Igs) which display one or more novel variable (V) region N-glycosylation motifs.	Nitrogen	232-233	BCL2 apoptosis regulator	Homo sapiens	140-145
19130057-0	2009	Activation of ER stress and inhibition of EGFR N-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib.	Nitrogen	47-48	epidermal growth factor receptor	Homo sapiens	42-46
19130057-1	2009	PURPOSE: The epidermal growth factor receptor (EGFR), an N-glycosylated transmembrane protein, is the target of erlotinib, an orally bioavailable agent approved for treatment of patients with non-small cell lung cancer (NSCLC).	Nitrogen	57-58	epidermal growth factor receptor	Homo sapiens	13-45
19130057-1	2009	PURPOSE: The epidermal growth factor receptor (EGFR), an N-glycosylated transmembrane protein, is the target of erlotinib, an orally bioavailable agent approved for treatment of patients with non-small cell lung cancer (NSCLC).	Nitrogen	57-58	epidermal growth factor receptor	Homo sapiens	47-51
19130057-2	2009	In this study, we examined whether inhibition of EGFR N-glycosylation and stimulation of endoplasmic reticulum (ER) stress by tunicamycin enhances erlotinib-induced growth inhibition in NSCLC cell lines.	Nitrogen	54-55	epidermal growth factor receptor	Homo sapiens	49-53
19501045-2	2009	It has been reported that gp130 has 11 potential N-glycosylation sites in the extracellular domain, and nine of them are actually N-glycosylated.	Nitrogen	49-50	interleukin 6 signal transducer	Mus musculus	26-31
19501045-2	2009	It has been reported that gp130 has 11 potential N-glycosylation sites in the extracellular domain, and nine of them are actually N-glycosylated.	Nitrogen	130-131	interleukin 6 signal transducer	Mus musculus	26-31
19501045-5	2009	In neuroepithelial cells treated with tunicamycin, an N-glycosylation inhibitor, unglycosylated form of gp130 was detected.	Nitrogen	54-55	interleukin 6 signal transducer	Mus musculus	104-109
19580319-4	2009	The structural features of this new family of nontoxic MRP1 inhibitors include a (thio)urea disubstituted with preferentially two alkyl groups at the terminal nitrogen and an additional fused aromatic ring.	Nitrogen	159-167	ATP binding cassette subfamily C member 1	Homo sapiens	55-59
19553107-3	2009	SAR exploration around the nitrogen of the aminoethyl appendage chain of 1 led to compounds that displayed low nanomolar activity in a PARP1 enzymatic assay.	Nitrogen	27-35	poly(ADP-ribose) polymerase 1	Homo sapiens	135-140
19652506-3	2009	By observing relationship between the compounds" physicochemical properties and APPI response, compounds with higher lipophilicity and less polar surface area were considered to be advantageous for APPI-MS. To provide information for applying APPI-MS to the analysis of hydrophilic drugs, approximate lower limit of calculated octanol-water partition coefficient and the higher limit of the number of oxygen and nitrogen atoms were determined to be -0.95 and 6, respectively.	Nitrogen	412-420	amyloid beta precursor protein	Homo sapiens	80-84
19578754-0	2009	CBP-mediated post-translational N-glycosylation of BRCA2.	Nitrogen	32-33	CREB binding protein	Homo sapiens	0-3
19578754-5	2009	It is possible that this novel CBP-mediated post-translational N-glycosylation activity alters the conformation of CBP-interacting proteins, leading to regulation of gene expression, cell growth and differentiation.	Nitrogen	63-64	CREB binding protein	Homo sapiens	31-34
19578754-5	2009	It is possible that this novel CBP-mediated post-translational N-glycosylation activity alters the conformation of CBP-interacting proteins, leading to regulation of gene expression, cell growth and differentiation.	Nitrogen	63-64	CREB binding protein	Homo sapiens	115-118
19764408-7	2009	Cotransfection of endoplasmic reticulum (ER) degradation enhancing alpha-mannosidase like protein (EDEM) accelerated the degradation of N-glycosylated PC.	Nitrogen	136-137	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	99-103
19491226-1	2009	CONTEXT: GH and IGF-I are nitrogen retaining and anabolic, but the impact of long-term exposure to supraphysiological GH and IGF-I, either from endogenous overproduction in acromegaly or exogenous sources, on skeletal muscle (SM) mass is not clear.	Nitrogen	26-34	insulin like growth factor 1	Homo sapiens	16-21
19551820-4	2009	Many genetic relationships between vaccine strains and epidemic isolates appearing in Taiwan before other global locations were also observed and recorded in addition to a gradual increase in the number of N-linked glycosylation sites on partial HA1 proteins since 1980.	Nitrogen	206-207	Rho GTPase activating protein 45	Homo sapiens	246-249
19652506-3	2009	By observing relationship between the compounds" physicochemical properties and APPI response, compounds with higher lipophilicity and less polar surface area were considered to be advantageous for APPI-MS. To provide information for applying APPI-MS to the analysis of hydrophilic drugs, approximate lower limit of calculated octanol-water partition coefficient and the higher limit of the number of oxygen and nitrogen atoms were determined to be -0.95 and 6, respectively.	Nitrogen	412-420	amyloid beta precursor protein	Homo sapiens	198-202
19652506-3	2009	By observing relationship between the compounds" physicochemical properties and APPI response, compounds with higher lipophilicity and less polar surface area were considered to be advantageous for APPI-MS. To provide information for applying APPI-MS to the analysis of hydrophilic drugs, approximate lower limit of calculated octanol-water partition coefficient and the higher limit of the number of oxygen and nitrogen atoms were determined to be -0.95 and 6, respectively.	Nitrogen	412-420	amyloid beta precursor protein	Homo sapiens	198-202
19548637-3	2009	Nitrogen atoms from pyridyl ligands complete the distorted-octahedral coordination around each Co(III).	Nitrogen	0-8	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	95-102
19346169-1	2009	We have generated a strain of mice lacking two DNA N-glycosylases of base excision repair (BER), NTH1 and NEIL1, homologs of bacterial Nth (endonuclease three) and Nei (endonuclease eight).	Nitrogen	48-49	nei endonuclease VIII-like 1 (E. coli)	Mus musculus	106-111
19438409-5	2009	In K562 cells, GPA was dimeric and N- and O-glycosylated similar to erythroid GPA.	Nitrogen	35-36	glycophorin A (MNS blood group)	Homo sapiens	15-18
19549906-0	2009	Overexpression of DPAGT1 leads to aberrant N-glycosylation of E-cadherin and cellular discohesion in oral cancer.	Nitrogen	43-44	cadherin 1	Homo sapiens	62-72
19549906-2	2009	The relationship between altered N-glycosylation and loss of E-cadherin adhesion in cancer, however, remains unclear.	Nitrogen	33-34	cadherin 1	Homo sapiens	61-71
19549906-11	2009	Our studies show for the first time that DPAGT1 is an upstream regulator of E-cadherin N-glycosylation status and adherens junction composition and suggest that dysregulation of DPAGT1 causes disturbances in intercellular adhesion in oral cancer.	Nitrogen	87-88	cadherin 1	Homo sapiens	76-86
19320950-0	2009	The effect of carbon and nitrogen sources on bovicin HC5 production by Streptococcus bovis HC5.	Nitrogen	25-33	CYCS pseudogene 1	Homo sapiens	91-94
19302302-0	2009	The role of GAP1 gene in the nitrogen metabolism of Saccharomyces cerevisiae during wine fermentation.	Nitrogen	29-37	amino acid permease GAP1	Saccharomyces cerevisiae S288C	12-16
19302302-1	2009	AIM: The aim of this study was to analyse the relevance of the general amino acid permease gene (GAP1) of the wine yeast Saccharomyces cerevisiae on nitrogen metabolism and fermentation performance.	Nitrogen	149-157	amino acid permease GAP1	Saccharomyces cerevisiae S288C	97-101
19302302-4	2009	The fermentation capacity of the gap1 mutant strain was impaired in the nitrogen-limited and -excessive conditions.	Nitrogen	72-80	amino acid permease GAP1	Saccharomyces cerevisiae S288C	33-37
19556054-11	2009	The effect of denitrification is further supported as mean groundwater NO3-N was significantly (P&lt;0.05) related to groundwater N2/Ar ratio, redox potential (Eh), dissolved O2 and N2 and was close to being significant with N2O (P=0.08).	Nitrogen	130-132	NBL1, DAN family BMP antagonist	Homo sapiens	71-74
19556054-11	2009	The effect of denitrification is further supported as mean groundwater NO3-N was significantly (P&lt;0.05) related to groundwater N2/Ar ratio, redox potential (Eh), dissolved O2 and N2 and was close to being significant with N2O (P=0.08).	Nitrogen	182-184	NBL1, DAN family BMP antagonist	Homo sapiens	71-74
19302302-7	2009	CONCLUSIONS: The Gap1 permease seems to be important during wine fermentations with low and high nitrogen content, not only because of its amino acid transporter role but also because of its function as an amino acid sensor.	Nitrogen	97-105	amino acid permease GAP1	Saccharomyces cerevisiae S288C	17-21
19320950-4	2009	Streptococcus bovis HC5 produced bovicin using a variety of carbon and nitrogen sources.	Nitrogen	71-79	CYCS pseudogene 1	Homo sapiens	20-23
19320950-9	2009	CONCLUSIONS: Streptococcus bovis HC5 is a versatile lactic acid bacterium that can utilize several carbon and nitrogen sources for bovicin HC5 production.	Nitrogen	110-118	CYCS pseudogene 1	Homo sapiens	33-36
19320950-9	2009	CONCLUSIONS: Streptococcus bovis HC5 is a versatile lactic acid bacterium that can utilize several carbon and nitrogen sources for bovicin HC5 production.	Nitrogen	110-118	CYCS pseudogene 1	Homo sapiens	139-142
19213929-3	2009	When exposed to 97% N(2)-3% CO(2) on postnatal day 4.5, unanesthetized Pet-1(-/-) mice required over four times longer than age-matched wild-type controls to initiate gasping following primary apnea.	Nitrogen	20-24	plasmacytoma expressed transcript 1	Mus musculus	71-76
21582700-1	2009	In the title complex, [Co(C(22)H(24)N(2)O(4))] H(2)O, the Co(II) atom is in an almost square-planar coordination environment involv-ing two O and two N atoms from the Schiff base ligand.	Nitrogen	36-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	58-64
19691248-5	2009	An average nitrogen flux of 0.88 g NO3(-) -N/m2 x d was observed.	Nitrogen	11-19	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
19248770-2	2009	Among these proteins, the mIL-31 derivative was the most efficiently secreted into the medium in a N-glycosylation-dependent manner.	Nitrogen	99-100	interleukin 31	Mus musculus	26-32
19416536-4	2009	RESULTS: The four N-linked glycosylation sequons within the activation peptide were all occupied in bovine TAFI, similar to human TAFI, while the sequon located within the enzyme moiety of the bovine protein was non-glycosylated.	Nitrogen	18-19	carboxypeptidase B2	Bos taurus	107-111
19420742-5	2009	In addition, we also discuss the potential roles of N-glycosylation sites on integrin alpha5 subunit.	Nitrogen	52-53	integrin subunit alpha 5	Homo sapiens	77-92
18804984-0	2009	Relationship between n-3 and n-6 plasma fatty acid levels and insulin resistance in coronary patients with and without metabolic syndrome.	Nitrogen	7-8	insulin	Homo sapiens	62-69
19301917-4	2009	Dinitrogen is coordinated to the {Nb(III)(mu-H)(2)Nb(III)} core in a side-on/end-on manner, accompanied by the reductive elimination of H(2).	Nitrogen	0-10	familial progressive hyperpigmentation 1	Homo sapiens	42-46
19301917-6	2009	Two electrons are prepared for the cleavage of the N-N single bond through the mu-H migration to an N atom, leading to the formation of an Nb-Nb bond.	Nitrogen	51-52	familial progressive hyperpigmentation 1	Homo sapiens	79-83
19301917-8	2009	Finally, {Nb(mu-N)(2)Nb}(2-) is generated after H(2) elimination in which the N-bonded H atom is coupled with the remaining mu-H atom.	Nitrogen	10-11	familial progressive hyperpigmentation 1	Homo sapiens	124-128
19339248-6	2009	In contrast, the placement of the SCN(-) ion in the structure of myeloperoxidase (MPO) occurs with an opposite orientation, in which the nitrogen atom is closer to the heme iron than the sulfur atom.	Nitrogen	137-145	myeloperoxidase	Homo sapiens	65-80
19339248-6	2009	In contrast, the placement of the SCN(-) ion in the structure of myeloperoxidase (MPO) occurs with an opposite orientation, in which the nitrogen atom is closer to the heme iron than the sulfur atom.	Nitrogen	137-145	myeloperoxidase	Homo sapiens	82-85
19454038-0	2009	Potential antitumor effects of nitrogen-containing bisphosphonate in hormone receptor negative breast cancer patients with bone metastases.	Nitrogen	31-39	nuclear receptor subfamily 4 group A member 1	Homo sapiens	69-85
19416692-6	2009	The amino acid sequence deduced from the cDNA sequence revealed that many essential structural features were conserved in emu RBP including 18 cysteine residues, 2 N-glycosylation sites, a clustered phosphorylation region, and riboflavin-binding sites.	Nitrogen	43-44	riboflavin binding protein	Gallus gallus	126-129
19416692-7	2009	Two additional potential N-glycosylation sites were found in the amino acid sequences of RBPs from the emu and other sources such as the turtle and frog, which might in part account for the greater content of oligosaccharide chain of emu RBP as compared to chicken RBP.	Nitrogen	25-26	riboflavin binding protein	Gallus gallus	89-92
19416692-7	2009	Two additional potential N-glycosylation sites were found in the amino acid sequences of RBPs from the emu and other sources such as the turtle and frog, which might in part account for the greater content of oligosaccharide chain of emu RBP as compared to chicken RBP.	Nitrogen	25-26	riboflavin binding protein	Gallus gallus	238-241
19276077-0	2009	An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1,4-N-acetylglucosaminyltransferase III.	Nitrogen	3-4	integrin subunit alpha 5	Homo sapiens	60-75
19397750-0	2009	AKINbeta1 is involved in the regulation of nitrogen metabolism and sugar signaling in Arabidopsis.	Nitrogen	43-51	5'-AMP-activated protein kinase beta-2 subunit protein	Arabidopsis thaliana	0-9
19397750-8	2009	The results indicate that AKINbeta1 is involved in the regulation of nitrogen metabolism and sugar signaling.	Nitrogen	69-77	5'-AMP-activated protein kinase beta-2 subunit protein	Arabidopsis thaliana	26-35
19825636-5	2009	Phenotypic similarities with other mutants displaying root swelling suggest that PHT4;6 likely functions in protein N-glycosylation and cell wall biosynthesis, which are essential for salt tolerance.	Nitrogen	116-117	phosphate transporter 1;5	Arabidopsis thaliana	81-87
19301197-3	2009	Following N-hydroxylation, O-acetylation catalysed by N-acetyltransferase 2 (NAT2) is considered a further possible activation pathway.	Nitrogen	10-11	arylamine N-acetyltransferase 2	Cricetulus griseus	54-75
19301197-3	2009	Following N-hydroxylation, O-acetylation catalysed by N-acetyltransferase 2 (NAT2) is considered a further possible activation pathway.	Nitrogen	10-11	arylamine N-acetyltransferase 2	Cricetulus griseus	77-81
21706644-2	2009	One copolymer, DNPIM-33, has an excellent combination of properties with good film-forming characteristics and gas transport performance, and exhibits higher selectivity than the corresponding spirobisindane-based homopolymer PIM-1 for gas pairs, such as O(2) /N(2) , with a corresponding small decrease in permeability.	Nitrogen	16-17	Pim-1 proto-oncogene, serine/threonine kinase	Homo sapiens	226-231
19248770-4	2009	Introduction of the signal sequence from mIL-31 to human p53 protein failed to secrete the products, but further addition of the N-glycosylation site resulted in constitutive secretion of biologically active p53 protein into the medium in the N-glycosylated form.	Nitrogen	129-130	tumor protein p53	Homo sapiens	208-211
19248770-4	2009	Introduction of the signal sequence from mIL-31 to human p53 protein failed to secrete the products, but further addition of the N-glycosylation site resulted in constitutive secretion of biologically active p53 protein into the medium in the N-glycosylated form.	Nitrogen	243-244	tumor protein p53	Homo sapiens	208-211
19124464-1	2009	Epidermal growth factor receptor (EGFR), an N-glycosylated transmembrane protein with an intracellular kinase domain, undergoes dimerization by ligand binding resulting in activation of the kinase domain and phosphorylation.	Nitrogen	44-45	epidermal growth factor receptor	Homo sapiens	0-32
20107545-2	2009	Recently, it has been shown that N-glycosylation affects the binding activity of the Tim-3-Ig fusion protein to its ligand, galectin-9, but the binding properties of non-glycosylated Tim-3 on CD4(+)CD25(+) T cells has not been fully examined.	Nitrogen	33-34	galectin 9	Homo sapiens	124-134
20107545-2	2009	Recently, it has been shown that N-glycosylation affects the binding activity of the Tim-3-Ig fusion protein to its ligand, galectin-9, but the binding properties of non-glycosylated Tim-3 on CD4(+)CD25(+) T cells has not been fully examined.	Nitrogen	33-34	CD4 molecule	Homo sapiens	192-195
19107881-6	2009	These experiments were further complemented by analysis of the N-glycosylation patterns of the PSMA/PSM" proteins and by site-directed mutagenesis.	Nitrogen	63-64	folate hydrolase 1	Homo sapiens	95-99
19107881-6	2009	These experiments were further complemented by analysis of the N-glycosylation patterns of the PSMA/PSM" proteins and by site-directed mutagenesis.	Nitrogen	63-64	folate hydrolase 1	Homo sapiens	100-104
19107881-9	2009	Furthermore, the PSM" protein is N-glycosylated by a mixture of high-mannose and complex type oligosaccharides and therefore trafficked beyond the cis-Golgi compartment.	Nitrogen	33-34	folate hydrolase 1	Homo sapiens	17-21
19307599-3	2009	Defective N-glycosylation reduces cell surface expression by impairing both early secretory and endocytic traffic of CFTR.	Nitrogen	10-11	CF transmembrane conductance regulator	Homo sapiens	117-121
19307599-6	2009	These results suggest that cotranslational N-glycosylation can exert a chaperone-independent profolding change in the energetic of CFTR in vivo as well as outline a paradigm for the peripheral trafficking defect of membrane proteins with impaired glycosylation.	Nitrogen	43-44	CF transmembrane conductance regulator	Homo sapiens	131-135
19295141-7	2009	Using a novel technique for targeted activation of neurons, we show that the highly stereotyped wing expansion motor patterns can be initiated by stimulation of N(CCAP), a small network of central neurons that regulates the release of bursicon.	Nitrogen	161-162	Crustacean cardioactive peptide	Drosophila melanogaster	163-167
18437557-2	2009	A common single nucleotide polymorphism in the human SHBG gene results in an amino acid substitution (Asp327Asn), which introduces an additional N-glycosylation site, and is associated with reduced breast cancer risk in postmenopausal women.	Nitrogen	145-146	sex hormone binding globulin	Homo sapiens	53-57
18379890-12	2009	Diurnal variation of Sulfur-dioxide and Nitrogen dioxide were found to have inverse relationship with visibility during fog which may be due to formation of secondary pollutants such as sulfate and to a lesser extent nitrates.	Nitrogen	40-48	zinc finger protein, FOG family member 1	Homo sapiens	120-123
19177595-6	2009	Point mutations of the putative N-glycosylation sites abolished the TM4SF5-specific TSAHC responsiveness.	Nitrogen	32-33	transmembrane 4 superfamily member 5	Mus musculus	68-74
19178134-3	2009	The N-nitroimino (NNO2) neonicotinoid pharmacophore is systematically replaced by N-nitrosoimino (NNO), N-formylimino [NC(O)H], N-alkyl- and N-arylcarbonylimino [NC(O)R], and N-alkoxy- and N-aryloxycarbonylimino [NC(O)OR] variants.	Nitrogen	4-5	membrane frizzled-related protein	Homo sapiens	18-22
19242108-7	2009	The enhanced apoptotic response was correlated with increased phosphorylation of N-terrninal p53-Ser15 and -Ser46 and increased expression of the pro-apoptotic Bax gene at both the mRNA and protein level.	Nitrogen	81-82	tumor protein p53	Homo sapiens	93-96
19124464-1	2009	Epidermal growth factor receptor (EGFR), an N-glycosylated transmembrane protein with an intracellular kinase domain, undergoes dimerization by ligand binding resulting in activation of the kinase domain and phosphorylation.	Nitrogen	44-45	epidermal growth factor receptor	Homo sapiens	34-38
19208482-4	2009	The cytotoxicity of some novel compounds for P-glycoprotein-positive cells is highly dependent on N-substituent at the terminal amino group of ethylenediamine moiety.	Nitrogen	98-99	ATP binding cassette subfamily B member 1	Homo sapiens	45-59
18836708-8	2009	CONCLUSIONS: Voriconazole inhibits the CYP3A-mediated N-demethylation of oxycodone, drastically increasing exposure to oral oxycodone.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	39-44
19124570-8	2009	Indeed the Ure2p prion domain has been shown to be important, though not essential, for the nitrogen catabolism regulatory role of the protein.	Nitrogen	92-100	glutathione peroxidase	Saccharomyces cerevisiae S288C	11-16
19054348-5	2009	When nitrogen was re-supplied, transcripts for main regulators of the pathway, PAP1/GL3 and PAP2/MYB12, fell to less than 1 and 0.1% of initial values, respectively, during 24 h in the 15-30 degrees C temperature range.	Nitrogen	5-13	MYB binding protein 1a	Homo sapiens	92-96
19054802-5	2009	Using high-performance liquid chromatography (HPLC) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analyses, we found that the N-glycosylation patterns of human erythropoietin (hEPO) secreted by stably transfected S2 cells were more complex following GlcNAcase suppression, which generated N-glycan structures with a terminal GlcNAc and/or galactose.	Nitrogen	176-177	erythropoietin	Homo sapiens	210-224
19240946-1	2009	Alkaloids from the plants of Amaryllidaceae family consists of an unique class of nitrogen-containing compounds showing diverse and significant biological activities, including anticancer and acetylcholinesterase (AChE) inhibitory activities.	Nitrogen	82-90	acetylcholinesterase (Cartwright blood group)	Homo sapiens	192-212
19240946-1	2009	Alkaloids from the plants of Amaryllidaceae family consists of an unique class of nitrogen-containing compounds showing diverse and significant biological activities, including anticancer and acetylcholinesterase (AChE) inhibitory activities.	Nitrogen	82-90	acetylcholinesterase (Cartwright blood group)	Homo sapiens	214-218
19054349-0	2009	Over-expression of STP13, a hexose transporter, improves plant growth and nitrogen use in Arabidopsis thaliana seedlings.	Nitrogen	74-82	Major facilitator superfamily protein	Arabidopsis thaliana	19-24
19054349-2	2009	The cloning and transgenic expression of one family member (STP13) enabled the manipulation of carbon (C) and nitrogen (N) metabolism in Arabidopsis.	Nitrogen	110-118	Major facilitator superfamily protein	Arabidopsis thaliana	60-65
19054349-3	2009	Transgenic seedlings constitutively over-expressing STP13 (STP13OX) had increased rates of glucose uptake, higher endogenous sucrose levels and accumulated more total C and biomass per plant when grown on soil-less media supplemented with 55 mM glucose and sufficient N (9 mM nitrate).	Nitrogen	268-269	Major facilitator superfamily protein	Arabidopsis thaliana	52-57
19054349-3	2009	Transgenic seedlings constitutively over-expressing STP13 (STP13OX) had increased rates of glucose uptake, higher endogenous sucrose levels and accumulated more total C and biomass per plant when grown on soil-less media supplemented with 55 mM glucose and sufficient N (9 mM nitrate).	Nitrogen	268-269	Major facilitator superfamily protein	Arabidopsis thaliana	59-66
18704946-6	2009	This binding mode places 5-HT deep in the binding pocket of the SERT with the 5-position near residue hSERT A169/dSERT D164 in transmembrane helix 3, the indole nitrogen next to residue Y176/Y171, and the ethylamine tail under residues F335/F327 and S336/S328 within 4 A of residue D98.	Nitrogen	161-169	solute carrier family 6 member 4	Homo sapiens	64-68
18704946-6	2009	This binding mode places 5-HT deep in the binding pocket of the SERT with the 5-position near residue hSERT A169/dSERT D164 in transmembrane helix 3, the indole nitrogen next to residue Y176/Y171, and the ethylamine tail under residues F335/F327 and S336/S328 within 4 A of residue D98.	Nitrogen	161-169	solute carrier family 6 member 4	Homo sapiens	102-107
19194013-1	2009	Mpr1 is an enzyme that catalyzes the N-acetylation of the toxic L-azetidine-2-carboxylic acid (AZC).	Nitrogen	37-38	proteasome regulatory particle lid subunit RPN11	Saccharomyces cerevisiae S288C	0-4
19128155-5	2009	The two terminal Co(II) ions contain a facial coordination environment (3N, 3O) comprising three imino nitrogen atoms and three phenolate oxygen atoms.	Nitrogen	103-111	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	17-23
18550228-2	2009	All of the new compounds prepared showed high AChE inhibitory activities, with compound 3e that has an N-hexyl-benzyl piperidine substituent on the nitrogen atom reaching the best inhibitory activity for AChE (IC(50)=5.62 nM).	Nitrogen	148-156	acetylcholinesterase (Cartwright blood group)	Homo sapiens	204-208
19185102-11	2009	Neonates delivered in the context of intraamniotic inflammation had higher serum blood urea nitrogen levels, which correlated significantly with AF IL-6 levels.	Nitrogen	92-100	interleukin 6	Homo sapiens	148-152
18853239-7	2009	FT-IR/ATR results showed the distinct amino absorption bands presented at 3352 cm(-1)and 1613 cm(-1) after modification and XPS binding energies of C(1s) at 285.5 eV and N(1s) at 399.0 eV verified the existence of C-N bond formation on the PET film surface.	Nitrogen	170-171	ATR serine/threonine kinase	Homo sapiens	6-9
19073345-9	2009	CONCLUSION: This study shows that CRP and neopterin have a role in differentiating bacterial from viral causes of ARTI, and the C/N ratio yields optimal differentiation in the ED setting.	Nitrogen	2-3	C-reactive protein	Homo sapiens	34-37
18981290-2	2009	ADAMTS13 contains 10 putative N-glycosylation sites in or near its metalloprotease sequence, spacer region, thrombospondin type 1 repeat no.	Nitrogen	30-31	A disintegrin and metalloproteinase with thrombospondin motifs 13	Cricetulus griseus	0-8
19111842-2	2009	Both disulfide bond formation and N-glycosylation are critical check points determining the stability and degradation fate of ABCG2 protein in the endoplasmic reticulum (ER).	Nitrogen	34-35	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	126-131
18957377-2	2009	The proton-coupled di- and tripeptide transporter PepT1 (SLC15a1) is the major route by which dietary nitrogen is taken up from the small intestine, as well as being the route of entry for important therapeutic (pro)drugs such as the beta-lactam antibiotics, angiotensin-converting enzyme inhibitors and antiviral and anti-cancer agents.	Nitrogen	102-110	solute carrier family 15 member 1	Homo sapiens	50-55
18957377-2	2009	The proton-coupled di- and tripeptide transporter PepT1 (SLC15a1) is the major route by which dietary nitrogen is taken up from the small intestine, as well as being the route of entry for important therapeutic (pro)drugs such as the beta-lactam antibiotics, angiotensin-converting enzyme inhibitors and antiviral and anti-cancer agents.	Nitrogen	102-110	solute carrier family 15 member 1	Homo sapiens	57-64
18826430-4	2009	Legume-specific symbiotic nitrogen fixation is under the control of the putative transcription factor, NIN, in Lotus japonicus.	Nitrogen	26-34	nin	Lotus japonicus	103-106
18981290-10	2009	Thus, N-glycosylation is necessary for efficient secretion of ADAMTS13, while conversion of the N-glycans from oligomannose to complex type in the Golgi complex enhances the proteolytic activity of the protease toward VWF multimers.	Nitrogen	6-7	A disintegrin and metalloproteinase with thrombospondin motifs 13	Cricetulus griseus	62-70
19167329-0	2009	Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoforms.	Nitrogen	38-39	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	92-95
19167329-3	2009	Using siRNA to achieve isoform-specific knockdowns, we show that the OST isoforms cooperate and act sequentially to mediate protein N-glycosylation.	Nitrogen	9-10	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	69-72
19167329-7	2009	These distinct and complementary roles for the OST isoforms allow sequential scanning of polypeptides for acceptor sites to insure the maximal efficiency of N-glycosylation.	Nitrogen	157-158	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	47-50
20943123-7	2009	We discuss recent advances in our understanding of the key mechanisms which confer bacterial resistance to nitrogen species, which in response to nitric oxide include the flavohemoglobin, HmpA, the flavorubredoxin, NorV, and the cytochrome c nitrite reductase, NrfA, whilst in response to nitrate include a repertoire of nitrate reductases.	Nitrogen	107-115	cytochrome c, somatic	Homo sapiens	229-241
19601803-5	2009	Typical CYP2D6 substrates are usually lipophilic bases with a planar hydrophobic aromatic ring and a nitrogen atom which can be protonated at physiological pH, but several atypical substrates such as spirosulfonamide and pactimibe do not contain a basic nitrogen atom.	Nitrogen	101-109	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	8-14
20407596-5	2009	The results obtained showed that CD24 is both N- and O-glycosylated.	Nitrogen	46-47	CD24 molecule	Homo sapiens	33-37
19035590-0	2009	Selective benzylic and allylic alkylation of protic nucleophiles with sulfonamides through double Lewis acid catalyzed cleavage of sp3 carbon-nitrogen bonds.	Nitrogen	142-150	Sp3 transcription factor	Homo sapiens	131-134
19035592-0	2009	Coupling of nitrogen heteroaromatics and alkanes without transition metals: a new oxidative cross-coupling at C-H/C-H bonds.	Nitrogen	12-20	churchill domain containing 1	Homo sapiens	110-117
19116994-0	2009	Titanium-catalyzed hydroaminoalkylation of alkenes by C-H bond activation at sp3 centers in the alpha-position to a nitrogen atom.	Nitrogen	116-124	Sp3 transcription factor	Homo sapiens	77-80
19027295-2	2009	The carbamate functionality and a small hydrophobic substituent in the C-3 position were found to be vital for the binding affinity to the nAChRs, whereas the carbamate nitrogen substituents were important for nAChR subtype selectivity.	Nitrogen	169-177	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	139-144
19160097-9	2009	NS-398 dose-dependently decreased the levels of COX-2 mRNA, COX-2 protein, nuclear NF-kappaB protein and production of PGF(1alpha) and increased the cytoplasmic IkappaB protein.	Nitrogen	0-2	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	48-53
19160097-9	2009	NS-398 dose-dependently decreased the levels of COX-2 mRNA, COX-2 protein, nuclear NF-kappaB protein and production of PGF(1alpha) and increased the cytoplasmic IkappaB protein.	Nitrogen	0-2	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	60-65
19160097-9	2009	NS-398 dose-dependently decreased the levels of COX-2 mRNA, COX-2 protein, nuclear NF-kappaB protein and production of PGF(1alpha) and increased the cytoplasmic IkappaB protein.	Nitrogen	0-2	nuclear factor kappa B subunit 1	Homo sapiens	83-92
19601803-5	2009	Typical CYP2D6 substrates are usually lipophilic bases with a planar hydrophobic aromatic ring and a nitrogen atom which can be protonated at physiological pH, but several atypical substrates such as spirosulfonamide and pactimibe do not contain a basic nitrogen atom.	Nitrogen	254-262	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	8-14
19635745-9	2009	Removal of N-linked sugar residues by Endo H treatment reduced XET activity to 60%.	Nitrogen	11-12	xyloglucan:xyloglucosyl transferase 33	Arabidopsis thaliana	63-66
19645588-5	2009	Typical CYP2D6 substrates are usually lipophilic bases with an aromatic ring and a nitrogen atom, which can be protonated at physiological pH.	Nitrogen	83-91	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	8-14
19385255-6	2009	The shift of C (1s) peak position could be ascribed to the chemical bonding between carbon and nitrogen atoms even though more three-fold coordinated sp2 configuration as in graphite was formed when the films were doped with more nitrogen atoms.	Nitrogen	230-238	Sp2 transcription factor	Homo sapiens	150-153
19385255-9	2009	It was shown that the tetrahedral hybridization component was still dominant even though the ratio of sp2/sp3 obtained from C(1s) spectra rose with the increase in nitrogen content.	Nitrogen	164-172	Sp2 transcription factor	Homo sapiens	102-105
19385255-9	2009	It was shown that the tetrahedral hybridization component was still dominant even though the ratio of sp2/sp3 obtained from C(1s) spectra rose with the increase in nitrogen content.	Nitrogen	164-172	Sp3 transcription factor	Homo sapiens	106-109
19277547-0	2009	LC/MSn for glycoprotein analysis: N-linked glycosylation analysis and peptide sequencing of glycopeptides.	Nitrogen	34-35	moesin	Homo sapiens	3-6
18704111-8	2009	We conclude that dermal N-acetylation of PPD competes with the formation of oxidized PPD whereas skin exposure conditions allowing auto-oxidation, as in the LLNA, provide an effective danger signal necessary to induce skin sensitization to PPD.	Nitrogen	24-25	4-hydroxyphenylpyruvate dioxygenase	Homo sapiens	41-44
18979233-7	2009	Some upregulated genes, such as Slc38a5 and Slc1a7 encoding glutamine transporters, may be parts of the total body adaptation to alleviate negative nitrogen balance.	Nitrogen	148-156	solute carrier family 1 member 7	Rattus norvegicus	44-50
19158958-10	2009	Exposure to N-LDL versus HOG-LDL induced similar phosphorylation of ERK, p38, and JNK, peaking at 5 min, with similar dose-dependent responses up to 25 mg/l that were constant from 25 to 100 mg/l.	Nitrogen	12-13	mitogen-activated protein kinase 1	Homo sapiens	68-71
19158958-10	2009	Exposure to N-LDL versus HOG-LDL induced similar phosphorylation of ERK, p38, and JNK, peaking at 5 min, with similar dose-dependent responses up to 25 mg/l that were constant from 25 to 100 mg/l.	Nitrogen	12-13	mitogen-activated protein kinase 14	Homo sapiens	73-76
19158958-10	2009	Exposure to N-LDL versus HOG-LDL induced similar phosphorylation of ERK, p38, and JNK, peaking at 5 min, with similar dose-dependent responses up to 25 mg/l that were constant from 25 to 100 mg/l.	Nitrogen	12-13	mitogen-activated protein kinase 8	Homo sapiens	82-85
19422547-0	2009	The importance of cytosolic glutamine synthetase in nitrogen assimilation and recycling.	Nitrogen	52-60	glutamate-ammonia ligase	Homo sapiens	28-48
19422547-1	2009	Glutamine synthetase assimilates ammonium into amino acids, thus it is a key enzyme for nitrogen metabolism.	Nitrogen	88-96	glutamate-ammonia ligase	Homo sapiens	0-20
19422547-2	2009	The cytosolic isoenzymes of glutamine synthetase assimilate ammonium derived from primary nitrogen uptake and from various internal nitrogen recycling pathways.	Nitrogen	90-98	glutamate-ammonia ligase	Homo sapiens	28-48
19422547-2	2009	The cytosolic isoenzymes of glutamine synthetase assimilate ammonium derived from primary nitrogen uptake and from various internal nitrogen recycling pathways.	Nitrogen	132-140	glutamate-ammonia ligase	Homo sapiens	28-48
19422547-3	2009	In this way, cytosolic glutamine synthetase is crucial for the remobilization of protein-derived nitrogen.	Nitrogen	97-105	glutamate-ammonia ligase	Homo sapiens	23-43
19422547-5	2009	Members of the cytosolic glutamine synthetase gene family are regulated in response to plant nitrogen status, as well as to environmental cues, such as nitrogen availability and biotic/abiotic stresses.	Nitrogen	93-101	glutamate-ammonia ligase	Homo sapiens	25-45
19422547-5	2009	Members of the cytosolic glutamine synthetase gene family are regulated in response to plant nitrogen status, as well as to environmental cues, such as nitrogen availability and biotic/abiotic stresses.	Nitrogen	152-160	glutamate-ammonia ligase	Homo sapiens	25-45
19759441-8	2009	At pH 9.5 and an initial NO3- concentration of 10 mg L(-1) NO3--N, the concentration of NO2- produced was above 0.1 mg L(-1) NO2--N, the Germany drinking water standard.	Nitrogen	25-26	NBL1, DAN family BMP antagonist	Homo sapiens	59-62
19514453-1	2009	The authors have earlier demonstrated that CBA/N mice bearing nonsense mutation in the btk gene encoding B cell Bruton"s thyrosine kinase after CG vaccination develop no protective response against subsequent M. tuberculosis H37Rv challenge.	Nitrogen	47-48	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	87-90
18842621-7	2009	Rat mammary cells cultured in the medium supplemented 24 h with 10muM ABP showed downregulation in the N-and O-acetylation of all substrates tested except for the NAT1-selective substrate SMZ.	Nitrogen	103-104	glutamate receptor interacting protein 2	Rattus norvegicus	70-73
18842621-9	2009	These studies clearly show NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in rat mammary epithelial cell cultures to be subject to downregulation by the arylamine carcinogen ABP.	Nitrogen	27-28	glutamate receptor interacting protein 2	Rattus norvegicus	230-233
18930737-6	2008	The amino acid sequence of PIP contains one potential N-glycosylation site at Asn77, and the same is found glycosylated with four sugar residues.	Nitrogen	54-55	prolactin induced protein	Homo sapiens	27-30
19053771-1	2008	The recently discovered mammalian molybdoprotein mARC1 is capable of reducing N-hydroxylated compounds.	Nitrogen	78-79	mitochondrial amidoxime reducing component 2	Mus musculus	49-54
19055736-3	2008	Deoxyuridine triphosphatase (dUTPase) hydrolyzes dUTP, generating dUMP for biosynthesis of thymidine nucleotides while decreasing the availability of dUTP for misincorporation; uracil DNA glycosylase (UNG) cleaves uracil N-glycosylic bonds in DNA initiating base excision repair.	Nitrogen	185-186	uracil DNA glycosylase	Homo sapiens	201-204
19090996-7	2008	The following review describes how targeting NADPH oxidase can reduce a broad spectrum of toxic factors (for example, cytokines, ROS, and reactive nitrogen species) to result in inhibition of neuronal damage from two triggers of deleterious microglial activation (Abeta and neuron damage), offering hope in halting the progression of AD.	Nitrogen	147-155	amyloid beta precursor protein	Homo sapiens	264-269
18708589-5	2008	Here we show that plasma N-Hcy-protein levels are significantly elevated in CBS- and MTHFR-deficient patients.	Nitrogen	25-26	cystathionine beta-synthase	Homo sapiens	76-79
19143230-5	2008	Milk fat proportions of conjugated linoleic acid (CLA), C18:3 c9,c12,c15, total n-3 and polyunsaturated FA (PUFA) were highest (p &lt; 0.05) with diet OC and higher in the lowlands than in the highlands.	Nitrogen	18-19	Weaning weight-maternal milk	Bos taurus	0-4
18653264-1	2008	Nitrate (NO3-) is often observed in surface waters draining terrestrial ecosystems that remain strongly nitrogen (N) limited.	Nitrogen	104-112	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
18653264-7	2008	Transitory exceedance of microbial N-uptake capacity during periods of high water and N flux may therefore provide a mechanism for NO3- leaching.	Nitrogen	35-36	NBL1, DAN family BMP antagonist	Homo sapiens	131-134
18653264-7	2008	Transitory exceedance of microbial N-uptake capacity during periods of high water and N flux may therefore provide a mechanism for NO3- leaching.	Nitrogen	86-87	NBL1, DAN family BMP antagonist	Homo sapiens	131-134
21581217-1	2008	In the title compound, [Co(C(8)H(8)NO(3))(2)], the Co(II) atom lies on a centre of inversion and is coordinated in a slightly distorted square-planar geometry by two N and two O atoms from the 2-hydroxy-imino-methyl-6-methoxy-phenolate ligands.	Nitrogen	35-36	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	51-57
19513290-8	2008	The predialysis serum blood urea nitrogen (BUN) level in the dialysis patients with RLS was significantly correlated with RLS symptom severity.	Nitrogen	33-41	RLS1	Homo sapiens	84-87
19513290-8	2008	The predialysis serum blood urea nitrogen (BUN) level in the dialysis patients with RLS was significantly correlated with RLS symptom severity.	Nitrogen	33-41	RLS1	Homo sapiens	122-125
19038947-10	2008	The apparent efficiency of N utilization for milk N production increased from 27.7% on the 11.3% RDP diet to 38.6% on the 7.6% RDP diet.	Nitrogen	27-28	Weaning weight-maternal milk	Bos taurus	45-49
19038947-10	2008	The apparent efficiency of N utilization for milk N production increased from 27.7% on the 11.3% RDP diet to 38.6% on the 7.6% RDP diet.	Nitrogen	50-51	Weaning weight-maternal milk	Bos taurus	45-49
18462937-5	2008	The optimum COD/N ratio was found to be 3.4, achieving 98% nitrate removal in 7h at a maximum rate of 30.4mg NO3- -N/gVSSh and very low residual COD in the effluent.	Nitrogen	16-17	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
18809682-1	2008	The second step of eukaryotic N-linked glycosylation in endoplasmic reticulum is catalyzed by an UDP-N-acetylglucosamine transferase that is comprised of two subunits, Alg13 and Alg14.	Nitrogen	30-31	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14	Saccharomyces cerevisiae S288C	178-183
18783838-0	2008	Characterisation of the endogenous human peripheral serotonin transporter SLC6A4 reveals surface expression without N-glycosylation.	Nitrogen	116-117	solute carrier family 6 member 4	Homo sapiens	74-80
18834188-2	2008	Novel compounds combining a 5-HT 1A moiety (3-aminochroman scaffold) and a 5-HT transporter (indole analogues) linked through a common basic nitrogen via an alkyl chain attached at the 1- or 3-position of the indole were evaluated for dual affinity at both the 5-HT reuptake site and the 5-HT 1A receptor.	Nitrogen	141-149	solute carrier family 6 member 4	Rattus norvegicus	75-91
21581110-1	2008	In the title complex, [Co(C(15)H(14)NO)(2)], the Co(II) atom, situated on an inversion centre, is coordinated by two O and two N atoms from two symmetry-related bidentate Schiff base ligands in a slightly distorted square-planar geometry.	Nitrogen	36-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	49-55
18462383-5	2008	Moreover, we demonstrate that Ure2p/Gln3p proteins mainly control the bioconversion of volatile thiols by the transcriptional regulation of the IRC7 gene through the general mechanism of nitrogen catabolic repression.	Nitrogen	187-195	glutathione peroxidase	Saccharomyces cerevisiae S288C	30-35
19194944-6	2008	Elemental analysis of MAPA for nitrogen was estimated as 0.42 mmol/g polymer.	Nitrogen	31-39	leucine rich repeat containing 25	Homo sapiens	22-26
18725510-0	2008	The molecular basis of CYP2D6-mediated N-dealkylation: balance between metabolic clearance routes and enzyme inhibition.	Nitrogen	39-40	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	23-29
18725510-3	2008	The CYP2D6 pharmacophore and characteristic features in the active site cavity suggest a favored substrate orientation that prevents N-dealkylation from occurring.	Nitrogen	133-134	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	4-10
18725510-4	2008	In this study, the literature was searched for N-dealkylated and non-N-dealkylated CYP2D6 substrates.	Nitrogen	69-70	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	83-89
18462383-5	2008	Moreover, we demonstrate that Ure2p/Gln3p proteins mainly control the bioconversion of volatile thiols by the transcriptional regulation of the IRC7 gene through the general mechanism of nitrogen catabolic repression.	Nitrogen	187-195	cysteine-S-conjugate beta-lyase IRC7	Saccharomyces cerevisiae S288C	144-148
18946143-6	2008	An increase in milk urea nitrogen was associated with decreasing 56-d nonreturn rates on the phenotypic scale.	Nitrogen	25-33	Weaning weight-maternal milk	Bos taurus	15-19
18491227-2	2008	In a previous study, we demonstrated that all of four potential N-glycosylation sites in E-cadherin are occupied by N-glycans in human breast carcinoma cells in vivo and the elimination of N-glycan at Asn-633 dramatically affected E-cadherin expression and made it degraded.	Nitrogen	64-65	cadherin 1	Homo sapiens	89-99
18491227-2	2008	In a previous study, we demonstrated that all of four potential N-glycosylation sites in E-cadherin are occupied by N-glycans in human breast carcinoma cells in vivo and the elimination of N-glycan at Asn-633 dramatically affected E-cadherin expression and made it degraded.	Nitrogen	64-65	cadherin 1	Homo sapiens	231-241
18491227-3	2008	In this study we investigated the molecular mechanism of E-cadherin, which lacks N-glycosylation at Asn-633 (M4), degradation and the role of the N-glycan at Asn-633 in E-cadherin folding.	Nitrogen	81-82	cadherin 1	Homo sapiens	57-67
18491227-9	2008	In conclusion, this study revealed that N-glycosylation at Asn-633 is essential for E-cadherin expression, folding and trafficking.	Nitrogen	40-41	cadherin 1	Homo sapiens	84-94
18521746-2	2008	To understand the significance of N-glycosylation in the pathogenesis of early-onset familial Alzheimer"s disease (AD) and in beta-amyloid (Abeta) production, we examined whether the mutations in the amyloid precursor protein (APP) gene found in familial AD affect the N-glycans on APP.	Nitrogen	34-35	amyloid beta precursor protein	Homo sapiens	200-225
18946143-1	2008	The aims of the study were to evaluate the relationships among milk urea nitrogen and nonreturn rates at the phenotypic scale, and to estimate genetic parameters among milk urea nitrogen, milk yield, and fertility traits in the early period of lactation.	Nitrogen	73-81	Weaning weight-maternal milk	Bos taurus	63-67
18946143-13	2008	The genetic correlation between milk yield and milk urea nitrogen was 0.44, reflecting an energy deficiency in early lactation.	Nitrogen	57-65	Weaning weight-maternal milk	Bos taurus	32-36
18946143-13	2008	The genetic correlation between milk yield and milk urea nitrogen was 0.44, reflecting an energy deficiency in early lactation.	Nitrogen	57-65	Weaning weight-maternal milk	Bos taurus	47-51
18604229-9	2008	Pharmacological and in silico investigations concerning the interactions of these compounds with the hERG channel revealed that compounds carrying a basic nitrogen in the side chain display a much higher affinity than those lacking such a group.	Nitrogen	155-163	ETS transcription factor ERG	Homo sapiens	101-105
18800828-0	2008	Neglected bidentate sp2 N-donor carrier ligands with triazine nitrogen lone pairs: platinum complexes retromodeling cisplatin guanine nucleobase adducts.	Nitrogen	62-70	Sp2 transcription factor	Homo sapiens	20-23
18983076-1	2008	Nitrate (NO3) profiles in semiarid unsaturated zones archive land use change (LUC) impacts on nitrogen (N) cycling with implications for agricultural N management and groundwater quality.	Nitrogen	94-102	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
18983076-6	2008	This NO3 most likely originated from cultivation causing mineralization and nitrification of soil organic nitrogen (SON) in old soil water (precultivation) and is attributed to enhanced microbial activity caused by increased soil wetness beneath cropland (median matric potential -42 m) relative to that beneath natural ecosystems (median -211 m).	Nitrogen	106-114	NBL1, DAN family BMP antagonist	Homo sapiens	5-8
18512733-2	2008	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia.	Nitrogen	12-13	vesicle associated membrane protein 2	Homo sapiens	121-158
18512733-2	2008	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia.	Nitrogen	12-13	vesicle associated membrane protein 2	Homo sapiens	160-165
18827937-5	2008	Ligand substitution in trans-[PtCl2(PhCN)(N=C(Ph)-O-N(Me)-CR1R2)] allows for selective replacement of the coordinated nitrile by nitrogen heterocycles such as pyridine, DMAP or 1-benzyl-2-methylimidazole to produce mixed ligand Pt(II) complexes of the type trans- [PtX2(heterocycle)(N=C(Ph)-O-N(Me)-CR1R2)].	Nitrogen	129-137	paired like homeodomain 2	Homo sapiens	265-269
18829313-0	2008	Human serum albumin as a catalyst of RNA cleavage: N-homocysteinylation and N-phosphorylation by oligonucleotide affinity reagent alter the reactivity of the protein.	Nitrogen	38-39	albumin	Homo sapiens	12-19
18772341-8	2008	Administering C5aR siRNA to mice preserved renal function from I/R injury, as evidenced by reduced levels of serum creatinine and blood urea nitrogen in the treated groups.	Nitrogen	141-149	complement component 5a receptor 1	Mus musculus	14-18
18647303-8	2008	Using recombinant CYP3A4, N-dealkylation was characterized by a K(m) of 13 microM and a V(max) of 3 pmol pmol(-1) CYP min(-1).	Nitrogen	26-27	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	18-24
18691229-9	2008	Beriplex P/N showed the greatest capacity for thrombin inhibition, a reflection of the observed high levels of the coagulation inhibitors protein C, protein S, protein Z, and small amounts of antithrombin III and heparin in this product.	Nitrogen	11-12	coagulation factor II, thrombin	Homo sapiens	46-54
18543263-6	2008	This condition has been shown to promote insulin resistance by interfering with phosphorylation of proteins of the insulin pathway including insulin receptor substrate-1/2 (IRS), phosphatidylinositol-3-kinase, (PI3-kinase) and protein kinase C. Although the molecular mechanism is not completely understood, elevated reactive oxygen (ROS) and nitrogen species (RNS) are involved in this process.	Nitrogen	343-351	insulin	Homo sapiens	41-48
18543263-6	2008	This condition has been shown to promote insulin resistance by interfering with phosphorylation of proteins of the insulin pathway including insulin receptor substrate-1/2 (IRS), phosphatidylinositol-3-kinase, (PI3-kinase) and protein kinase C. Although the molecular mechanism is not completely understood, elevated reactive oxygen (ROS) and nitrogen species (RNS) are involved in this process.	Nitrogen	343-351	insulin	Homo sapiens	115-122
18543263-6	2008	This condition has been shown to promote insulin resistance by interfering with phosphorylation of proteins of the insulin pathway including insulin receptor substrate-1/2 (IRS), phosphatidylinositol-3-kinase, (PI3-kinase) and protein kinase C. Although the molecular mechanism is not completely understood, elevated reactive oxygen (ROS) and nitrogen species (RNS) are involved in this process.	Nitrogen	343-351	insulin	Homo sapiens	115-122
18409193-0	2008	Weak self-association of human growth hormone investigated by nitrogen-15 NMR relaxation.	Nitrogen	62-70	growth hormone 1	Homo sapiens	31-45
18803335-6	2008	The program has been tested on tryptic digests of two glycopeptides: AGP (which has five different N-glycosylation sites) and transferrin (with two N-glycosylation sites).	Nitrogen	148-149	transferrin	Homo sapiens	126-137
18524873-1	2008	Typical CYP2D6 substrates generally contain a basic nitrogen atom that interacts with Asp(301) and/or Glu(216) and an aromatic moiety adjacent to the site of metabolism.	Nitrogen	52-60	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	8-14
18242769-3	2008	Regardless of nitrogen treatments, PAL1 and 2 transcript levels increased at 5 and 10 degrees C. Averaged across all temperatures, nitrogen depletion led to a two-fold increase in PAL1 and PAL2 transcripts.	Nitrogen	131-139	PHE ammonia lyase 1	Arabidopsis thaliana	35-45
18242769-3	2008	Regardless of nitrogen treatments, PAL1 and 2 transcript levels increased at 5 and 10 degrees C. Averaged across all temperatures, nitrogen depletion led to a two-fold increase in PAL1 and PAL2 transcripts.	Nitrogen	131-139	PHE ammonia lyase 1	Arabidopsis thaliana	35-39
19123362-5	2008	The results showed that the application of synthetic nitrogen fertilizer could bring about a carbon sequestration potential of 21.9 Tg C x a(-1) in current situation, and 30.2 Tg C x a(-1) with fertilization as recommended.	Nitrogen	53-61	transglutaminase 2	Homo sapiens	132-136
19123362-5	2008	The results showed that the application of synthetic nitrogen fertilizer could bring about a carbon sequestration potential of 21.9 Tg C x a(-1) in current situation, and 30.2 Tg C x a(-1) with fertilization as recommended.	Nitrogen	53-61	transglutaminase 2	Homo sapiens	176-180
18708057-5	2008	Our data also revealed that hOLFML1 is N-glycosylated and its secretion is triggered by serum.	Nitrogen	39-40	olfactomedin like 1	Homo sapiens	28-35
18524873-9	2008	The effect of the N-alkyl chain length of pactimibe analogs on their CYP2D6 metabolic stability was plausibly explained by the docking model.	Nitrogen	18-19	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	69-75
18549807-0	2008	N-glycosylation modulates the cell-surface expression and catalytic activity of corin.	Nitrogen	0-1	corin, serine peptidase	Mus musculus	80-85
18650100-5	2008	Examination of the energy landscapes obtained for combinations of these parameters showed that a low internal energy region (&lt;or=1.0 eV) was present at nitrogen flow rates between 2 and 4 L min(-1) and capillary temperatures up to 250 degrees C using ESI (9% of all parameter combinations tested).	Nitrogen	155-163	CD59 molecule (CD59 blood group)	Homo sapiens	193-199
18769671-8	2008	CONCLUSIONS: Together, these findings attribute an apoptogenic role to N-AChE-S and outline a potential value to AChE inhibitor therapeutics in early AD.	Nitrogen	2-3	acetylcholinesterase (Cartwright blood group)	Homo sapiens	73-77
18769671-8	2008	CONCLUSIONS: Together, these findings attribute an apoptogenic role to N-AChE-S and outline a potential value to AChE inhibitor therapeutics in early AD.	Nitrogen	2-3	acetylcholinesterase (Cartwright blood group)	Homo sapiens	113-117
18764640-4	2008	The results are described by a model in which the nitrogen activity produced by surface-catalyzed NH3 decomposition varies with the exposed surface areas of GaN, InN, and In.	Nitrogen	50-58	growth hormone releasing hormone	Homo sapiens	162-165
18656365-6	2008	We report here the design and synthesis of N-heterocycle-containing analogues of alpha-tocopherol that act as inhibitors of Cyp4F2, the key monooxygenase responsible for omega-hydroxylation of the side chain of tocols.	Nitrogen	43-44	cytochrome P450 family 4 subfamily F member 2	Homo sapiens	124-130
18800519-6	2008	delta15N (NO3) values are significantly related (p &lt; 0.05) to wet deposition of inorganic N, sulfate, and acidity, suggesting that spatial variability of delta15N (NO3) over the Rocky Mountains may be related to source areas of these solutes.	Nitrogen	7-8	NBL1, DAN family BMP antagonist	Homo sapiens	10-13
18800519-6	2008	delta15N (NO3) values are significantly related (p &lt; 0.05) to wet deposition of inorganic N, sulfate, and acidity, suggesting that spatial variability of delta15N (NO3) over the Rocky Mountains may be related to source areas of these solutes.	Nitrogen	7-8	NBL1, DAN family BMP antagonist	Homo sapiens	167-170
18766255-8	2008	Cotransfection of endoplasmic reticulum (ER) degradation enhancing alpha-mannosidase-like protein (EDEM) accelerated the degradation of N-glycosylated PC.	Nitrogen	136-137	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	99-103
18549807-1	2008	N-glycosylation may influence the subcellular localization and biological activity of the pro-ANP convertase, corin.	Nitrogen	0-1	corin, serine peptidase	Mus musculus	110-115
18549807-2	2008	In HEK293-corin cells, the inhibition of N-glycosylation, with tunicamycin, reduced the cell-surface expression of murine corin, but did not alter the total expression.	Nitrogen	41-42	corin, serine peptidase	Mus musculus	10-15
18549807-2	2008	In HEK293-corin cells, the inhibition of N-glycosylation, with tunicamycin, reduced the cell-surface expression of murine corin, but did not alter the total expression.	Nitrogen	41-42	corin, serine peptidase	Mus musculus	122-127
18549807-5	2008	We developed an assay to measure the effect of N-glycosylation on corin activity, independent of its effect on corin localization.	Nitrogen	47-48	corin, serine peptidase	Mus musculus	66-71
18549807-6	2008	We determined that the reduction in corin activity was due to a direct effect of N-glycosylation, and was not secondary to the effect of N-glycosylation on corin cell-surface expression.	Nitrogen	81-82	corin, serine peptidase	Mus musculus	36-41
18549807-7	2008	Our data provide evidence that N-glycosylation is essential for the cell-surface expression of murine corin and modulates its functional activity.	Nitrogen	31-32	corin, serine peptidase	Mus musculus	102-107
18549807-8	2008	N-Glycosylation represents a possible mechanism for the regulation of native corin on the surface of cardiomyocytes.	Nitrogen	0-1	corin, serine peptidase	Mus musculus	77-82
18630913-4	2008	Reaction with PPh3 results in nitrogen atom transfer to the phosphine, supporting a reaction mechanism involving nucleophilic attack of the triphenylphosphine HOMO at the electrophilic LUMO of the iron nitrido complex.	Nitrogen	30-38	caveolin 1	Homo sapiens	14-18
18593178-2	2008	Seven commercially available HA products designed for babies up to 4 months showed a potent inhibition of ACE in vitro, with IC 50 values ranging between 3.2 and 68.5 mg of nitrogen/L.	Nitrogen	173-181	angiotensin I converting enzyme	Homo sapiens	106-109
18642254-6	2008	A 3D HNC-TEDOR (transferred-echo double-resonance) experiment with deuterated CA150.WW2 fibrils yielded 14 amide nitrogen and proton resonance assignments.	Nitrogen	113-121	transcription elongation regulator 1	Homo sapiens	78-83
18410483-2	2008	Sugar-induced ABI4 regulates plant genes essential for photosynthesis, and carbon, nitrogen and lipid metabolism.	Nitrogen	83-91	Integrase-type DNA-binding superfamily protein	Arabidopsis thaliana	14-18
25983975-3	2008	Overproduction of an N-form of PTH other than PTH (1-84) has been observed in the sera of these patients.	Nitrogen	21-22	parathyroid hormone	Homo sapiens	31-34
18614909-3	2008	Recombinant growth hormone supplementation in surgical trauma and burn injury patients has demonstrated nitrogen retention, increased insulin-like growth factor-1 levels, decreased length of stay and improved survival.	Nitrogen	104-112	growth hormone 1	Homo sapiens	12-26
18614909-5	2008	RECENT FINDINGS: Small clinical trials have revisited growth hormone supplementation in prolonged critical illness, demonstrating nitrogen conservation and increased serum levels of insulin-like growth factor-1 and insulin-like growth factor-1 binding protein in patients receiving adequate nutrition support.	Nitrogen	130-138	growth hormone 1	Homo sapiens	54-68
18613280-3	2008	Our work deals with the analysis by electrospray ionization tandem mass spectrometry (ESI-MSn) of the well-known nitrogen-containing HMBP alendronate and of three analogues, considered as potential prodrugs.	Nitrogen	113-121	moesin	Homo sapiens	90-93
18646010-6	2008	siRNA targeting LGALS3, WBSCR17, PHF3, SDC2 and CTNNAL1 partially reversed the GlcNAc-induced phenotypes, suggesting a role for galectin-3/N-glycans, proteoglycans, O-glycans, and junctional cell adhesion.	Nitrogen	3-4	PHD finger protein 3	Homo sapiens	33-37
18646010-6	2008	siRNA targeting LGALS3, WBSCR17, PHF3, SDC2 and CTNNAL1 partially reversed the GlcNAc-induced phenotypes, suggesting a role for galectin-3/N-glycans, proteoglycans, O-glycans, and junctional cell adhesion.	Nitrogen	3-4	catenin alpha like 1	Homo sapiens	48-55
18607003-4	2008	In the mammalian OST complex one such subunit, ribophorin I, is proposed to facilitate the N-glycosylation of certain precursors during their biogenesis at the endoplasmic reticulum.	Nitrogen	91-92	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	17-20
18691144-3	2008	Due to glutamine synthetase activity, inorganic nitrogen is incorporated in the cell metabolism and is further used in biosynthesis of several highly important metabolites.	Nitrogen	48-56	glutamate-ammonia ligase	Homo sapiens	7-27
18671849-11	2008	VEGF was significantly reduced following the treatment of NS-398 in A549 (by 31%) and MOR/P (by 47%) cells lines which expressing strong COX-2, but not in H460 cell line which expressing very low COX-2.	Nitrogen	58-60	vascular endothelial growth factor A	Homo sapiens	0-4
18671849-11	2008	VEGF was significantly reduced following the treatment of NS-398 in A549 (by 31%) and MOR/P (by 47%) cells lines which expressing strong COX-2, but not in H460 cell line which expressing very low COX-2.	Nitrogen	58-60	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	137-142
18671849-11	2008	VEGF was significantly reduced following the treatment of NS-398 in A549 (by 31%) and MOR/P (by 47%) cells lines which expressing strong COX-2, but not in H460 cell line which expressing very low COX-2.	Nitrogen	58-60	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	196-201
18571420-2	2008	Introduction of a bulky N-alkyl group, such as a cyclohexylmethyl or benzyl group, increased the binding affinity for wild-type AR and the potency for growth inhibition of androgen-dependent SC-3 cells.	Nitrogen	24-25	androgen receptor	Homo sapiens	128-130
18418832-2	2008	The dipeptide mimetic, which respectively displayed the side chains of tryptophan and lysine at the nitrogen and O6 atoms of the iminosugar scaffold is a ligand (K(i)=3.2 microM) for the human somatostatin receptor subtype 4 (hSSTR4) but has lower affinity (K(i)&gt;100 microM) for hSSTR5.	Nitrogen	100-108	somatostatin receptor 4	Homo sapiens	226-232
18371179-7	2008	Primary cultured microglial cells subjected to hypoxia (3% oxygen, 5% CO(2) and 92% nitrogen) showed enhanced expression of TNF-alpha and IL-1beta.	Nitrogen	84-92	tumor necrosis factor	Rattus norvegicus	124-133
18371179-7	2008	Primary cultured microglial cells subjected to hypoxia (3% oxygen, 5% CO(2) and 92% nitrogen) showed enhanced expression of TNF-alpha and IL-1beta.	Nitrogen	84-92	interleukin 1 beta	Rattus norvegicus	138-146
18578693-3	2008	MATERIALS AND METHODS: Circulating and hepatic redox active and nitrogen regulating molecules thioredoxin, glutathione, protein thiols (PSH), mixed disulfides (PSSG), NO metabolites nitrosothiols, nitrite plus nitrate (NOx), and lipid peroxides (TBARs) were measured in rats fed a choline deprived (CD) diet for 30 days.	Nitrogen	64-72	thioredoxin 1	Rattus norvegicus	94-105
18457328-10	2008	CONCLUSIONS: The current findings suggested that the T/N expression ratios of ATM and DNA-PKcs may be useful for identifying NSCLC patients with a poor prognosis who may benefit from more aggressive therapy.	Nitrogen	2-3	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	86-94
18844165-9	2008	The IR spectrum absorbance bands of bovine serum albumin and BPA appeared on the IR spectrum graph of artificial antigen of BPA, moreover, shrinked vibration bands at 1 000-1 300 cm(-1) showed that a C-N bond was produced and suggested that the modified BPA and BSA had been linked.	Nitrogen	202-203	albumin	Homo sapiens	43-56
21202804-2	2008	The Fe(III) cation is chelated by three Schiff base ligands via three N and three O atoms, and exhibits a slightly distorted octa-hedral geometry.	Nitrogen	70-71	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	7-10
21202733-2	2008	The Co(II) center is six-coordinated by four N atoms from one bis-[4-(2-pyrid-yl)pyrimidin-2-yl] sulfide (L) ligand and two bromide anions, forming an octa-hedral coordination geometry, where the four donor N atoms are located in the equatorial plane and the Br atoms occupy the axial positions.	Nitrogen	45-46	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
21202733-2	2008	The Co(II) center is six-coordinated by four N atoms from one bis-[4-(2-pyrid-yl)pyrimidin-2-yl] sulfide (L) ligand and two bromide anions, forming an octa-hedral coordination geometry, where the four donor N atoms are located in the equatorial plane and the Br atoms occupy the axial positions.	Nitrogen	207-208	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-10
18439678-4	2008	Both porcine TLR7 and TLR8 proteins were expressed in cell lines and were N-glycosylated.	Nitrogen	74-75	toll like receptor 7	Homo sapiens	13-17
18536736-10	2008	CONCLUSIONS: Inhibition of IL-13-dependent eotaxin-1 release by heparin involved but did not depend upon sulphation, though loss of N-sulphation reduced the attenuating activity, which could be restored by N-acetylation.	Nitrogen	2-3	interleukin 13	Homo sapiens	27-32
18536736-10	2008	CONCLUSIONS: Inhibition of IL-13-dependent eotaxin-1 release by heparin involved but did not depend upon sulphation, though loss of N-sulphation reduced the attenuating activity, which could be restored by N-acetylation.	Nitrogen	2-3	C-C motif chemokine ligand 11	Homo sapiens	43-52
18496372-0	2008	Frequent intravenous pulses of growth hormone together with glutamine supplementation in prolonged critical illness after multiple trauma: effects on nitrogen balance, insulin resistance, and substrate oxidation.	Nitrogen	150-158	growth hormone 1	Homo sapiens	31-45
18496372-13	2008	CONCLUSIONS: Treatment with frequent intravenous pulses of low-dose growth hormone together with alanyl-glutamine supplementation improves nitrogen economy in patients with prolonged critical illness after multiple trauma but worsens insulin sensitivity.	Nitrogen	139-147	growth hormone 1	Homo sapiens	68-82
18439678-4	2008	Both porcine TLR7 and TLR8 proteins were expressed in cell lines and were N-glycosylated.	Nitrogen	74-75	toll like receptor 8	Homo sapiens	22-26
18483264-5	2008	Using the N-linked glycosylation inhibitor, tunicamycin, we show that expression levels of several RTKS (EGFR, ErbB2, ErbB3, and IGF-IR) are exquisitely sensitive to inhibition of N-linked glycosylation.	Nitrogen	10-11	epidermal growth factor receptor	Homo sapiens	105-109
21202506-2	2008	The Co(III) ion is hexa-coordinated by three N and three O atoms from three bidentate Schiff base ligands in an octa-hedral geometry.	Nitrogen	45-46	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-11
18387312-7	2008	The Bbeta chain of the recombinant fibrinogen was N-glycosylated but the Aalpha chain, as in plasma fibrinogen, was not.	Nitrogen	50-51	fibrinogen beta chain	Homo sapiens	35-45
18393948-7	2008	The multiple forms of plant-derived recombinant hIL-13 (rhIL-13) are a result of differential N-linked glycosylation, as revealed by enzymatic and chemical deglycosylation, but not of disulphide-linked oligomerization.	Nitrogen	94-95	interleukin 13	Homo sapiens	48-54
18419255-4	2008	The CD61 intensity at the oliguric phase was inversely correlated with platelet count and serum albumin, and positively correlated with white blood cell count, blood urea nitrogen, serum creatinine, and alanine aminotransferase levels.	Nitrogen	171-179	integrin subunit beta 3	Homo sapiens	4-8
18445491-6	2008	Western blot assay revealed that CBA/N mice showed constant expression of Hsp70 and Hsp110 with age, but not in DBA/2J mice.	Nitrogen	37-38	heat shock protein 1B	Mus musculus	74-79
18412376-7	2008	The hydrophobic interactions decrease with increasing N of the series of PS-PME NMA and show a correlation with the amount of protein adsorbed.	Nitrogen	54-55	cystatin B	Homo sapiens	76-79
18260827-0	2008	N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).	Nitrogen	0-1	tweety family member 2	Homo sapiens	186-204
18260827-0	2008	N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).	Nitrogen	0-1	tweety family member 2	Homo sapiens	206-211
18260827-0	2008	N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).	Nitrogen	144-145	tweety family member 2	Homo sapiens	186-204
18260827-0	2008	N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2).	Nitrogen	144-145	tweety family member 2	Homo sapiens	206-211
18483264-5	2008	Using the N-linked glycosylation inhibitor, tunicamycin, we show that expression levels of several RTKS (EGFR, ErbB2, ErbB3, and IGF-IR) are exquisitely sensitive to inhibition of N-linked glycosylation.	Nitrogen	10-11	erb-b2 receptor tyrosine kinase 2	Homo sapiens	111-116
18483264-7	2008	Using U251 glioma and BXPC3 pancreatic adenocarcinoma cell lines, two cell lines resistant to epidermal growth factor receptor-targeted therapies, we show that inhibiting N-linked glycosylation markedly reduces RTK signaling through Akt and radiosensitizes tumor cells.	Nitrogen	171-172	AKT serine/threonine kinase 1	Homo sapiens	233-236
18256203-11	2008	In the context of the in vitro study of CYP3A4-mediated DDI using MDZ and ketoconazole, direct MDZ N-glucuronidation may partly compensate the decrease in MDZ metabolic clearance caused by the addition of the inhibitor, thus potentially leading to underestimation, at least in vitro, of the extent of DDI.	Nitrogen	99-100	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	40-46
18214858-2	2008	Haptoglobin, an acute phase protein, has four potential N-glycosylation sites, although it remains unknown which site is responsible for the change in fucosylated N-glycans.	Nitrogen	56-57	haptoglobin	Homo sapiens	0-11
18489081-9	2008	The DMPO adducts of MPO metabolism, as analyzed by electron spin resonance spectroscopy, included a nitrogen-centered radical and a phenyl radical derived from PA, either of which may be involved in the free radical formation on MPO.	Nitrogen	100-108	myeloperoxidase	Homo sapiens	5-8
18489081-9	2008	The DMPO adducts of MPO metabolism, as analyzed by electron spin resonance spectroscopy, included a nitrogen-centered radical and a phenyl radical derived from PA, either of which may be involved in the free radical formation on MPO.	Nitrogen	100-108	myeloperoxidase	Homo sapiens	20-23
18421771-1	2008	Glutamate synthases play with glutamine synthetase an essential role in nitrogen assimilation processes in microorganisms, plants, and lower animals by catalyzing the net synthesis of one molecule of L-glutamate from L-glutamine and 2-oxoglutarate.	Nitrogen	72-80	glutamate-ammonia ligase	Homo sapiens	30-50
18187349-2	2008	Isoelectrofocusing of plasma transferrin and apolipoprotein C-III showed abnormal patterns suggesting defective N- and O-glycosylation.	Nitrogen	112-113	transferrin	Homo sapiens	29-40
18391098-4	2008	Kallistatin treatment improved renal function and reduced kidney damage as evidenced by diminished proteinuria and serum urea nitrogen levels, glomerular sclerosis, tubular damage, and protein cast formation.	Nitrogen	126-134	serpin family A member 4	Rattus norvegicus	0-11
18425328-6	2008	This form of beta1 integrin was only recognized by the 9EG7 anti-beta1 antibody and appeared devoid of other specific antibody epitopes (12G10, TS2/16 and mAb13 shown here to be N-glycosylation sensitive).	Nitrogen	178-179	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	13-18
18397324-7	2008	These results indicate that PCaP1 tightly binds to the plasma membrane via N-myristoylation at Gly2.	Nitrogen	75-76	Metallo-hydrolase/oxidoreductase superfamily protein	Arabidopsis thaliana	95-99
21202222-1	2008	In the mol-ecule of the title compound, [Co(C(6)H(4)NO(2))(2)(H(2)O)(2)], the coordination environment around the Co(II) atom is distorted octahedral; two N and two O atoms of the pyridine-2-carboxylate ligands lie in the equatorial plane and the two water O atoms in the axial positions.	Nitrogen	52-53	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	114-120
17979184-0	2008	N-glycosylation affects the adhesive function of E-Cadherin through modifying the composition of adherens junctions (AJs) in human breast carcinoma cell line MDA-MB-435.	Nitrogen	0-1	cadherin 1	Homo sapiens	49-59
17979184-2	2008	The ectodomain of human E-cadherin contains four potential N-glycosylation sites at Asn residues 554, 566, 618, and 633.	Nitrogen	59-60	cadherin 1	Homo sapiens	24-34
17979184-3	2008	In this study, the role of N-glycosylation in E-cadherin-mediated cell-cell adhesion was investigated by site-directed mutagenesis.	Nitrogen	27-28	cadherin 1	Homo sapiens	46-56
17979184-4	2008	In MDA-MB-435 cells, all four potential N-glycosylation sites of human E-cadherin were N-glycosylated.	Nitrogen	40-41	cadherin 1	Homo sapiens	71-81
17979184-4	2008	In MDA-MB-435 cells, all four potential N-glycosylation sites of human E-cadherin were N-glycosylated.	Nitrogen	87-88	cadherin 1	Homo sapiens	71-81
17979184-9	2008	These findings demonstrate that N-glycosylation may affect the adhesive function of E-cadherin through modifying the composition of AJs.	Nitrogen	32-33	cadherin 1	Homo sapiens	84-94
18385850-1	2008	A series of propargylic tertiary alcohols decorated with an sp2-hybridised nitrogen donor were kinetically resolved by reagent-controlled dehydrogenative Si-O coupling with a strained, highly reactive silicon-stereogenic cyclic silane.	Nitrogen	75-83	Sp2 transcription factor	Homo sapiens	60-63
18337470-1	2008	The second step of dolichol-linked oligosaccharide synthesis in the N-linked glycosylation pathway at the endoplasmic reticulum (ER) membrane is catalyzed by an unusual hetero-oligomeric UDP-N-acetylglucosamine transferase that in most eukaryotes is comprised of at least two subunits, Alg13p and Alg14p.	Nitrogen	68-69	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14	Saccharomyces cerevisiae S288C	297-303
18298058-4	2008	When a mixed-nitrogen donor bidentate ligand, 2-(2-aminoethyl)pyridine, that has different coordination affinities for fac-Re(acac)(OH2)(CO)3 was utilized, a unique tridentate ligand was formed in situ utilizing a metal-assisted Schiff base formation to yield a complex fac-Re(CO)3(3[(2-phenylethyl)imino]-2-pentanone) (3).	Nitrogen	13-21	FA complementation group C	Homo sapiens	119-122
18298058-4	2008	When a mixed-nitrogen donor bidentate ligand, 2-(2-aminoethyl)pyridine, that has different coordination affinities for fac-Re(acac)(OH2)(CO)3 was utilized, a unique tridentate ligand was formed in situ utilizing a metal-assisted Schiff base formation to yield a complex fac-Re(CO)3(3[(2-phenylethyl)imino]-2-pentanone) (3).	Nitrogen	13-21	FA complementation group C	Homo sapiens	270-273
18245087-5	2008	Ure2 is required for Gln3 to be restricted to the cytoplasm of cells provided with good nitrogen sources, and Sit4 is required for its location to the nucleus following rapamycin treatment.	Nitrogen	88-96	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-4
18375764-3	2008	CyaA utilizes a heavily N-glycosylated beta(2) integrin receptor CD11b/CD18 (alpha(M)beta(2), Mac-1, or CR3).	Nitrogen	24-25	integrin subunit beta 2	Homo sapiens	71-75
18324787-0	2008	Cross-linking of the DNA repair protein Omicron6-alkylguanine DNA alkyltransferase to DNA in the presence of antitumor nitrogen mustards.	Nitrogen	119-127	X-ray repair cross complementing 6 pseudogene 5	Homo sapiens	21-39
18324787-4	2008	Here, we show that the DNA repair protein, O (6)-alkylguanine DNA alkyltransferase (AGT), can be readily cross-linked to DNA in the presence of nitrogen mustards.	Nitrogen	144-152	X-ray repair cross complementing 6 pseudogene 5	Homo sapiens	23-82
18354205-13	2008	Presence of Ag enhanced macaque IgA binding and blocking of macaque CD89 N-glycosylation reduced CD89 expression.	Nitrogen	73-74	Fc alpha receptor	Homo sapiens	68-72
18619289-8	2008	It was demonstrated that the thin film with low percentage of nitrogen was beneficial to the formation of sp3 hybrid bonds and caused the optical band gap of the thin film to increase.	Nitrogen	62-70	Sp3 transcription factor	Homo sapiens	106-109
18336412-9	2008	Milk urea nitrogen was lower for cows fed ground maize grain compared with cracked maize grain (118-134 mg/l, p = 0.05).	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
18354205-13	2008	Presence of Ag enhanced macaque IgA binding and blocking of macaque CD89 N-glycosylation reduced CD89 expression.	Nitrogen	73-74	Fc alpha receptor	Homo sapiens	97-101
18337501-6	2008	Whereas overexpression of EXT2 in HEK 293 cells enhanced NDST1 expression, increased NDST1 N-glycosylation, and resulted in elevated HS sulfation, overexpression of EXT1 had opposite effects.	Nitrogen	57-58	exostosin glycosyltransferase 2	Homo sapiens	26-30
18203712-1	2008	Cyclooxygenases (COX-1 and COX-2) are N-glycosylated, endoplasmic reticulum-resident, integral membrane proteins that catalyze the committed step in prostanoid synthesis.	Nitrogen	38-39	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	27-32
18311908-4	2008	In this study, the structural characteristics of nitrogen-containing compounds, which bind to the iron atom in two CYP isoforms (CYP2C9 and CYP3A4), were investigated.	Nitrogen	49-57	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	115-118
18311908-4	2008	In this study, the structural characteristics of nitrogen-containing compounds, which bind to the iron atom in two CYP isoforms (CYP2C9 and CYP3A4), were investigated.	Nitrogen	49-57	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	140-146
18211902-4	2008	N-Glycosylated scDb variants possessing 3, 6, or 9 N-glycosylation sites, respectively, retained antigen binding activity and bispecificity for target and effector cells as shown in a target cell-dependent IL-2 release assay, although activity was reduced approximately 3-5-fold compared with the unmodified scDb.	Nitrogen	0-1	interleukin 2	Homo sapiens	206-210
18241886-7	2008	The analysis of our Ec_ydjA structure explains its specificity for larger substrates and provides structural information for the rational design of novel prodrugs with the ability to reduce nitrogen-containing hazardous molecules.	Nitrogen	190-198	ydjA	Escherichia coli K-12	23-27
17975018-0	2008	N-linked glycosylation of VWF modulates its interaction with ADAMTS13.	Nitrogen	0-1	von Willebrand factor	Homo sapiens	26-29
18322210-0	2008	Identification of an N-linked glycosylation in the C4 region of HIV-1 envelope gp120 that is critical for recognition of neighboring CD4 T cell epitopes.	Nitrogen	21-22	CD4 molecule	Homo sapiens	133-136
18290647-3	2008	We show that the enzyme MccB, encoded by the MccC7 gene cluster, is responsible for formation of the N-P bond in MccC7.	Nitrogen	101-102	MccB	Escherichia coli	24-28
18258441-3	2008	However, the structural modification of D-AB1, such as its enantiomerization, epimerization at C-2 and/or C-3, introduction of a substituent to C-1, and replacement of the ring nitrogen by sulfur, markedly lowered or abolished its inhibition toward the enzyme.	Nitrogen	177-185	DAB adaptor protein 1	Homo sapiens	40-45
18291642-2	2008	Guided by X-ray crystallography of thrombin-inhibitor complexes and molecular modeling, alkylation of the N1 nitrogen of the imidazole P1 ligand of the pyridinoneacetamide thrombin inhibitor 1 with various acetamide moieties furnished inhibitors with significantly improved thrombin potency, trypsin selectivity, functional in vitro anticoagulant potency and in vivo antithrombotic efficacy.	Nitrogen	109-117	coagulation factor II, thrombin	Homo sapiens	172-180
18291642-2	2008	Guided by X-ray crystallography of thrombin-inhibitor complexes and molecular modeling, alkylation of the N1 nitrogen of the imidazole P1 ligand of the pyridinoneacetamide thrombin inhibitor 1 with various acetamide moieties furnished inhibitors with significantly improved thrombin potency, trypsin selectivity, functional in vitro anticoagulant potency and in vivo antithrombotic efficacy.	Nitrogen	109-117	coagulation factor II, thrombin	Homo sapiens	172-180
18292673-10	2008	RESULTS: At clinical concentrations, methadone enantiomer N-demethylation by recombinant CYPs 2B6, 3A4, and 2C19 was S &gt; R, S = R, and S &lt;&lt; R. Greater stereoselective metabolism (S &gt; R) occurred in livers expressing high levels of CYP2B6 compared with CYP3A4.	Nitrogen	58-59	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	264-270
18211037-5	2008	This idea is explored further by examining the electronic and geometric properties of the series CrnR2, where n and R are given by n = 1, benzene C6H6 as reference; n = 2, biphenyl (C6H5)2; n = 3, triphenylene C18H12; n = 3, coronene C24H18; and n = 4, dibenzopyrene C24H14.	Nitrogen	38-39	protocadherin alpha 6	Homo sapiens	97-102
18266357-8	2008	The electrostatic repulsion between the Sdelta atom of ERalpha Met421 and the acetonitrile group nitrogen atom of the ligand led to unfavorable binding.	Nitrogen	97-105	estrogen receptor 1	Homo sapiens	55-62
18269266-3	2008	For n-C3H7I, some small vibrational peaks are partially resolved (with separation of approximately 522 cm-1, corresponding to the RCH2 deformation frequency of the fragment n-C3H7) at 281.73, 279.71, and 304.67 nm.	Nitrogen	4-5	karyopherin subunit alpha 1	Homo sapiens	130-134
18046018-10	2008	Knockdown of Ae2.2 mRNA, of Ae2.1 mRNA, or of both with nontoxic or minimally toxic levels of N-morpholino oligomers produced no grossly detectable morphological phenotype, and preserved normal structure of the head and the pronephric duct at 24 h postfertilization.	Nitrogen	21-22	solute carrier family 4 member 2b	Danio rerio	13-18
18282491-6	2008	Similarly, NGF levels were higher in PDR patients than in controls and NPDR patients after adjusting for possible confounding factors such as age, gender, serum blood urea nitrogen, creatinine, and diabetic parameters.	Nitrogen	172-180	nerve growth factor	Homo sapiens	11-14
18036567-3	2008	We further determined the role of N-glycosylation of ErbB family.	Nitrogen	34-35	epidermal growth factor receptor	Homo sapiens	53-57
18036567-9	2008	Together with findings from other laboratories, it is suggested that N-glycosylation controls ErbB signaling by various mechanisms.	Nitrogen	69-70	epidermal growth factor receptor	Homo sapiens	94-98
18178736-0	2008	Identification of the archaeal alg7 gene homolog (encoding N-acetylglucosamine-1-phosphate transferase) of the N-linked glycosylation system by cross-domain complementation in Saccharomyces cerevisiae.	Nitrogen	59-60	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	31-35
18431264-12	2008	The mean serum concentrations of creatinine and blood urea nitrogen were significantly (p &lt; .05) lower in the hANP group than in the placebo group.	Nitrogen	59-67	natriuretic peptide A	Homo sapiens	113-117
17986252-5	2008	Three members of the VID and GID gene families, VID30/GID1, GID2, and VID28/GID5 are needed for the rapamycin or nitrogen starvation-induced degradation of the high-affinity hexose transporter Hxt7p is shown here.	Nitrogen	113-121	ubiquitin-protein ligase RMD5	Saccharomyces cerevisiae S288C	60-64
17999676-3	2008	Deletion of the genes encoding the transcriptional coactivators Rsc1p or Gcn5p impairs FLO11 transcription, which consequently leads to a loss of both haploid invasive growth and diploid pseudohyphae development upon glucose and nitrogen limitation, respectively.	Nitrogen	229-237	Flo11p	Saccharomyces cerevisiae S288C	87-92
18301741-10	2008	Negative feedback on TOR pathway function to restrict the expression of FLO11 under nitrogen starved condition and also with re-addition of nitrogen to starved cells.	Nitrogen	84-92	Flo11p	Saccharomyces cerevisiae S288C	72-77
18272752-6	2008	Nucleotide sequencing of WN25A viruses recovered from the brains of B-cell-deficient mice revealed that the conserved N-linked glycosylation site in the viral envelope protein was abolished by substitution of a serine residue at position 155.	Nitrogen	0-1	melanoma antigen	Mus musculus	159-175
18006192-6	2008	These proposed alternative cycles are energetically more efficient than, and incorporate an inherent mechanism for transporting nitrogen from presynaptic neurons to astrocytes in support of the coordinated activities of PAG and GS that is absent in, the glutamate-glutamine cycle.	Nitrogen	128-136	glutamate-ammonia ligase	Homo sapiens	228-230
18301741-11	2008	In general, we show that these global signaling pathways respond with specific sensitivity to regulate the expression of FLO11 under nitrogen limitation.	Nitrogen	133-141	Flo11p	Saccharomyces cerevisiae S288C	121-126
18235976-0	2008	N-glycosylation at Asn residues 554 and 566 of E-cadherin affects cell cycle progression through extracellular signal-regulated protein kinase signaling pathway.	Nitrogen	0-1	cadherin 1	Homo sapiens	47-57
18272968-2	2008	present a very strong correlation between mean lifetime net ecosystem production (NEP, defined as the net rate of carbon (C) accumulation in ecosystems) and wet nitrogen (N) deposition.	Nitrogen	161-169	membrane metalloendopeptidase	Homo sapiens	82-85
18083109-0	2008	Monosialylated biantennary N-glycoforms containing GalNAc-GlcNAc antennae predominate when human EPO is expressed in goat milk.	Nitrogen	27-28	erythropoietin	Homo sapiens	97-100
18155731-8	2008	The experiments revealed that N induces the intrinsic apoptotic pathway, resulting in processing of N at residues 400 and 403 by caspase-6 and/or caspase-3.	Nitrogen	30-31	caspase 3	Homo sapiens	146-155
18235976-10	2008	These findings implied that N-glycosylation might be crucial for E-cadherin-mediated suppression of cell cycle progression.	Nitrogen	28-29	cadherin 1	Homo sapiens	65-75
18275445-10	2008	Significant differences (p &lt; 0.0002) were noted by gender in all three variables in the CART model (blood urea nitrogen [BUN] &gt; or = 43 mg/dL, systolic blood pressure &lt; 115 mm Hg, and serum creatinine &gt; or = 2.75 mg/dL).	Nitrogen	114-122	CART prepropeptide	Homo sapiens	91-95
18235976-2	2008	The ectodomain of human E-cadherin contains four potential N-glycosylation sites at Asn residues 554, 566, 618, and 633.	Nitrogen	59-60	cadherin 1	Homo sapiens	24-34
18235976-4	2008	We showed previously that all four potential N-glycosylation sites of E-cadherin were N-glycosylated in human breast carcinoma MDA-MB-435 cells.	Nitrogen	45-46	cadherin 1	Homo sapiens	70-80
18235976-4	2008	We showed previously that all four potential N-glycosylation sites of E-cadherin were N-glycosylated in human breast carcinoma MDA-MB-435 cells.	Nitrogen	86-87	cadherin 1	Homo sapiens	70-80
17937402-0	2008	Retardation of the unfolding process by single N-glycosylation of ribonuclease A based on molecular dynamics simulations.	Nitrogen	47-48	ribonuclease pancreatic	Bos taurus	66-80
18160489-4	2008	Following subcellular fractionation, rAbcb6-V5 was observed as an N-glycosylated protein in fractions enriched with lysosomal/endosomal membrane proteins.	Nitrogen	66-67	ATP binding cassette subfamily B member 6	Rattus norvegicus	37-43
17502122-4	2008	The ATP binding pocket of Chk1 seems to be adaptable to substitution of the nitrogen of the imide E heterocycle with a hydroxymethyl group, allowing the fundamental hydrogen bond with the Glu(85) residue of the enzyme.	Nitrogen	76-84	checkpoint kinase 1	Homo sapiens	26-30
17998299-10	2008	Incubations with recombinant human uridine diphosphate glucuronosyltransferases (UGTs) indicated that the O-glucuronidation was catalyzed by UGT2B4 and UGT2B7, whereas the N-glucuronidation was catalyzed by UGT1A4.	Nitrogen	172-173	UDP glucuronosyltransferase family 2 member B4	Homo sapiens	141-147
18380152-4	2008	The amino acid sequences of the extracellular domains of GPA and GPC had no significant homology to those from other mammalian species, including humans, and had O-linked and/or N-linked glycosylation sites.	Nitrogen	178-179	glycophorin A (MNS blood group)	Homo sapiens	57-60
17764997-1	2008	Cytochrome P450 CYP2D6 is involved in the oxidation of well over 150 drugs and, in general, those which contain a basic nitrogen atom in the molecule.	Nitrogen	120-128	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	16-22
17725604-0	2008	Importance of N-linked glycosylation in the functional expression of murine CD1d1.	Nitrogen	14-15	CD1d1 antigen	Mus musculus	76-81
17725604-2	2008	CD1d1 is predicted to contain five potential N-linked glycosylation sites (asparagine residues at positions 25, 38, 60, 128, and 183).	Nitrogen	45-46	CD1d1 antigen	Mus musculus	0-5
18166271-2	2008	Microinfusions of N/OFQ (10 or 32pmol) into the central amygdala (ACE) increased the time spent in the open arms of the elevated plus-maze (anxiolytic-like effects), whereas microinfusions of N/OFQ (10, 32 or 100 pmol) into the basolateral amygdala (ABL) did not affect the time spent in the open arms.	Nitrogen	18-19	angiotensin I converting enzyme	Rattus norvegicus	66-69
17929051-2	2008	Loss-of-function mutants of HY5 and HYH revealed that these genes are essential for induction of a key enzyme in nitrogen assimilation, nitrate reductase (EC 1.7.1.1).	Nitrogen	113-121	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	28-31
17929051-2	2008	Loss-of-function mutants of HY5 and HYH revealed that these genes are essential for induction of a key enzyme in nitrogen assimilation, nitrate reductase (EC 1.7.1.1).	Nitrogen	113-121	nitrate reductase 1	Arabidopsis thaliana	136-153
18247311-9	2008	bFGF mRNA expression was lower in N-desulfated heparin group(2.60+/-0.56%)than that in 0.9% NaCl solution group(30.65+/-6.84%).	Nitrogen	7-8	fibroblast growth factor 2	Homo sapiens	0-4
18166271-3	2008	Moreover, microinfusions of N/OFQ (32 pmol) into the ACE impaired escape performance from the open arms of the elevated T-maze (anxiolytic-like effects), but did not change inhibitory avoidance of the open arms.	Nitrogen	28-29	angiotensin I converting enzyme	Rattus norvegicus	53-56
18166271-5	2008	These results indicate that the anxiolytic-like effects of N/OFQ might be due to impaired escape performance from the open arms and it implicates the N/OFQ system within the ACE in the mediation of panic action.	Nitrogen	59-60	angiotensin I converting enzyme	Rattus norvegicus	174-177
18163630-5	2008	Similar close C-N interactions are observed in the crystal structure of the more sterically demanding isocyanide adduct, [Ni(CNCy)(PCy2NBz2)2]2(BF4)2, 4.	Nitrogen	16-17	forkhead box G1	Homo sapiens	144-152
18166271-5	2008	These results indicate that the anxiolytic-like effects of N/OFQ might be due to impaired escape performance from the open arms and it implicates the N/OFQ system within the ACE in the mediation of panic action.	Nitrogen	150-151	angiotensin I converting enzyme	Rattus norvegicus	174-177
18689982-6	2008	In addition, we found that inhibition of N-glycosylation increased the ubiquitination and degradation of P-gp and CD147, and affected their function.	Nitrogen	41-42	ATP binding cassette subfamily B member 1	Homo sapiens	105-109
18039572-4	2008	Compounds 2a, 2c, 2e, and 2g-m having sp2 nitrogen, especially amide and urea derivatives, showed potent anticoagulant activity.	Nitrogen	42-50	Sp2 transcription factor	Rattus norvegicus	38-41
18411844-4	2008	The N,S-heterodisubstituted o-carborane containing a mercapto group, 1-(2"-pyridyl)-2-SH-1,2-closo-C2B10H10, 1, is one of the two examples of a rigid bidentate chelating (pyridine)N-C-C-C-S(H) motif having been structurally fully characterized.	Nitrogen	4-5	secretoglobin family 2B member 3, pseudogene	Homo sapiens	99-110
18411844-4	2008	The N,S-heterodisubstituted o-carborane containing a mercapto group, 1-(2"-pyridyl)-2-SH-1,2-closo-C2B10H10, 1, is one of the two examples of a rigid bidentate chelating (pyridine)N-C-C-C-S(H) motif having been structurally fully characterized.	Nitrogen	180-181	secretoglobin family 2B member 3, pseudogene	Homo sapiens	99-110
17986444-6	2008	Our results revealed an identical glycosylation and almost complete polysialylation of N-glycosylation sites 5 and 6 in polySia-NCAM irrespective of the enzyme present.	Nitrogen	87-88	neural cell adhesion molecule 1	Mus musculus	128-132
18070108-8	2008	Further studies investigating the interaction of BMP-6 with different ectodomains of type I receptors revealed that N-glycosylation at Asn73 of BMP-6 in the wrist epitope is crucial for recognition by the activin receptor type I.	Nitrogen	116-117	bone morphogenetic protein 6	Homo sapiens	49-54
18064734-7	2008	The efficient stacking approach provides LODs (S/N = 3) of 2.41, 0.59, 0.61, and 4.22 nM for trypsin inhibitor, HSA, beta-lactoglobulin, and lysozyme, respectively.	Nitrogen	49-50	lysozyme	Homo sapiens	117-149
18070108-8	2008	Further studies investigating the interaction of BMP-6 with different ectodomains of type I receptors revealed that N-glycosylation at Asn73 of BMP-6 in the wrist epitope is crucial for recognition by the activin receptor type I.	Nitrogen	116-117	bone morphogenetic protein 6	Homo sapiens	144-149
18070108-10	2008	Thus, flexibility within the binding epitope of BMP-6 and an unusual recognition motif, i.e. an N-glycosylation motif, possibly play an important role in type I receptor specificity of BMP-6.	Nitrogen	96-97	bone morphogenetic protein 6	Homo sapiens	185-190
18037334-1	2008	The mammalian proton-coupled peptide transporter PepT1 is the major route of uptake for dietary nitrogen, as well as the oral absorption of a number of drugs, including beta-lactam antibiotics and angiotensin-converting enzyme inhibitors.	Nitrogen	96-104	solute carrier family 15 member 1	Homo sapiens	49-54
17919965-1	2008	The general amino acid permease (Gap1p) of Saccharomyces cerevisiae is a broad range, low affinity permease that imports amino acids in cells growing on poor nitrogen sources.	Nitrogen	158-166	amino acid permease GAP1	Saccharomyces cerevisiae S288C	33-38
17803183-8	2008	(iv) None of these N-linked structures showed the expected presence of disialylated antennae with GalNAcbeta4(NeuAcalpha3)Galbeta3(NeuAcalpha6)GlcNAcbetaGal, or its analogue, despite cross-reactivity of prostate cancer haptoglobin with monoclonal antibody RM2.	Nitrogen	5-6	haptoglobin	Homo sapiens	219-230
18267946-3	2008	When compared with the wild-type (WT) control plants, the SAG12::ipt wheat plants exhibited delayed chlorophyll degradation only when grown under limited nitrogen (N) supply.	Nitrogen	154-162	senescence-associated gene 12	Arabidopsis thaliana	58-63
17932247-3	2008	A more than 2-fold increase in CD11b-positive macrophages in the kidney on day 2 preceded the increase in blood urea nitrogen (BUN) and serum creatinine (SCr).	Nitrogen	117-125	integrin alpha M	Mus musculus	31-36
18575103-8	2008	HPO-A, HPO-N, TPI-A, and TPI-N contained 3.02%-3.52% of nitrogen.	Nitrogen	56-64	triosephosphate isomerase 1	Homo sapiens	25-28
18098061-0	2008	Identification of cytochrome P450 enzymes responsible for N -dealkylation of a new oral erectogenic, mirodenafil.	Nitrogen	58-59	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	18-33
18085519-6	2008	The use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) coupled with the (18)O-labeled internal standard approach has allowed us to show that (i) the N-domain of ACE (N-ACE), but not the C-domain, selectively cleaves the Arg-5-His-6 bond in both peptides, and that (ii) N-ACE hydrolyzes the isoAsp-7 analogue more efficiently than the non-modified one.	Nitrogen	196-197	angiotensin I converting enzyme	Homo sapiens	208-211
21558711-9	2008	The data suggest that the DME activity of B. japonicum bacteroids plays a role in nodule metabolism and supports nitrogen fixation.	Nitrogen	113-121	NADP-dependent malic enzyme	Bradyrhizobium diazoefficiens USDA 110	26-29
17888468-15	2008	Characterization of transgenic poplar with ectopic expression of pine cytosolic glutamine synthetase under conditions of varying nitrogen availability.	Nitrogen	129-137	glutamate-ammonia ligase	Homo sapiens	80-100
18076768-4	2007	Sequence analysis identified the presence of Asn 362 (N362), a potential N-linked glycosylation site immediately N-terminal to CD4-binding site (CD4bs) residues in the C3 region of gp120, more frequently in A-R5 Envs than PA-R5 Envs.	Nitrogen	54-55	CD4 molecule	Homo sapiens	127-130
18197495-0	2008	[Impact of growth hormone with hypocaloric nutrition on nitrogen balance and blood glucose in patients after gastrointestinal operation].	Nitrogen	56-64	growth hormone 1	Homo sapiens	11-25
18197495-1	2008	OBJECTIVE: To evaluate the impact of recombinant human growth hormone (rhGH) combined with hypocaloric nutrition on nitrogen balance and blood glucose in patients after gastrointestinal operation.	Nitrogen	116-124	growth hormone 1	Homo sapiens	55-69
18197495-10	2008	CONCLUSION: Growth hormone combined with hypocaloric nutrition is effective and safe in promoting positive nitrogen balance and protein synthesis in post-operative patients, which is also beneficial to the improvement of nutritional status and prognosis.	Nitrogen	107-115	growth hormone 1	Homo sapiens	12-26
17959596-1	2007	The nifU and nifS genes encode the components of a cellular machinery dedicated to the assembly of [2Fe-2S] and [4Fe-4S] clusters required for growth under nitrogen-fixing conditions.	Nitrogen	156-164	iron-sulfur cluster assembly enzyme	Homo sapiens	4-8
18213972-1	2007	A century-long increase in nitrate (NO3-) in the water column of Lake Superior is a classic example of recent nitrogen accumulation in ecosystems, but its cause and relationship to historical NO3- deposition is unknown.	Nitrogen	110-118	NBL1, DAN family BMP antagonist	Homo sapiens	36-39
18213973-2	2007	In this study we used the delta15N-NO3 signature in a watershed dominated by agriculture as an integrating marker to trace (1) the effects of the land cover and agricultural practices on stream-water N concentration in the upstream area of the hydrographic network, (2) influence of the in-stream processes on the NO3-N loads at the reach scale (100 m and 1000 m long), and (3) changes in delta15N-NO3 signature with increasing stream order (from first to third order).	Nitrogen	33-34	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
27517826-4	2007	When COD/NO3 (-)-N ratio (C/N) was in the range 5-30, the removal of benzene was slightly influenced by C/N and it remained stable at about 90%.	Nitrogen	17-18	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
17823199-6	2007	In healthy control samples, we determined 98-100% occupancy for all N-glycosylation sites of transferrin and alpha(1)-antitrypsin.	Nitrogen	68-69	transferrin	Homo sapiens	93-104
17823199-9	2007	In transferrin, a preferred occupancy for the first N-glycosylation site was observed, and a decreasing preference for the first, third, and second N-glycosylation sites was observed in alpha(1)-antitrypsin.	Nitrogen	52-53	transferrin	Homo sapiens	3-14
17823199-9	2007	In transferrin, a preferred occupancy for the first N-glycosylation site was observed, and a decreasing preference for the first, third, and second N-glycosylation sites was observed in alpha(1)-antitrypsin.	Nitrogen	148-149	serpin family A member 1	Homo sapiens	186-206
17999052-2	2007	N-[3-(1H-Imidazol-4-yl)propyl)]guanidines and N (G)-acylated derivatives are more efficacious and potent agonists at fusion proteins of the guinea pig histamine H(2) receptor and the short splice variant of G(salpha), G(salphaS) (gpH(2)R-G(salphaS)) than at the human isoform (hH(2)R-G(salphaS)).	Nitrogen	0-1	histamine H2 receptor	Cavia porcellus	151-174
17951459-0	2007	Antisense repression of the Medicago truncatula nodule-enhanced sucrose synthase leads to a handicapped nitrogen fixation mirrored by specific alterations in the symbiotic transcriptome and metabolome.	Nitrogen	104-112	sucrose synthase 5	Medicago truncatula	64-80
17898699-4	2007	Repeated intravenous doses of cationized catalase significantly decreased cisplatin-induced changes in serum creatinine, blood urea nitrogen, nitrite/nitrate levels, lactic dehydrogenase activity, and renal total glutathione and malondialdehyde contents.	Nitrogen	132-140	catalase	Mus musculus	41-49
18156219-4	2007	One of these factors, bZIP28, an ER-resident transcription factor, is activated in response to treatment by tunicamycin (TM), an agent that blocks N-linked protein glycosylation.	Nitrogen	147-148	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	22-28
27517826-4	2007	When COD/NO3 (-)-N ratio (C/N) was in the range 5-30, the removal of benzene was slightly influenced by C/N and it remained stable at about 90%.	Nitrogen	17-18	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
17948975-4	2007	The crystal structure of an optimized inhibitor, 4 (SC-806), in complex with p38 enzyme was obtained to confirm the hypothesis that the addition of a basic nitrogen to the molecule induces an interaction with Asp112 of p38 alpha.	Nitrogen	156-164	mitogen-activated protein kinase 14	Homo sapiens	77-80
17948975-4	2007	The crystal structure of an optimized inhibitor, 4 (SC-806), in complex with p38 enzyme was obtained to confirm the hypothesis that the addition of a basic nitrogen to the molecule induces an interaction with Asp112 of p38 alpha.	Nitrogen	156-164	mitogen-activated protein kinase 14	Homo sapiens	219-228
17574283-0	2007	Milk urea-nitrogen negatively affected first-service breeding success in commercial dairy cows in Prince Edward Island, Canada.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
17574283-1	2007	Our objective of this study was to investigate the relationship between milk urea-nitrogen concentrations ([MUN]) and first-service breeding success (FSBS) in a large number of commercial dairy herds, using various timings on [MUN].	Nitrogen	82-90	Weaning weight-maternal milk	Bos taurus	72-76
17929845-5	2007	The BDD/(NO3-) interface was the only N2O and N2 species generating system.	Nitrogen	38-40	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
17929845-4	2007	Among the three nitrogen oxides gases, NO2 substantially modifies the electrolyte via hydrolysis leading to the formation of NO3- and its adsorption on the BDD electrode surface.	Nitrogen	16-24	NBL1, DAN family BMP antagonist	Homo sapiens	125-128
17660267-5	2007	RESULTS: Withdrawal of insulin resulted in increased plasma glucose, branched chain amino acids, nonesterified fatty acids, beta-hydroxybutyrate, and urinary nitrogen but no change in bicarbonate.	Nitrogen	158-166	insulin	Homo sapiens	23-30
17973536-0	2007	C-C, C-O, C-N bond formation on sp2 carbon by Pd(II)-catalyzed reactions involving oxidant agents.	Nitrogen	12-13	Sp2 transcription factor	Homo sapiens	32-35
17887662-6	2007	Various N-alkylisatins were also found to dramatically alter lymphocyte morphology, destabilize microtubules, inhibit tubulin polymerization, induce G2/M cell cycle arrest, and activate the effector caspase-3 and -7.	Nitrogen	8-9	caspase 3	Homo sapiens	199-215
17499462-7	2007	Highly pure N-glycosylated recombinant GDNF has been obtained similar to the endogenous protein.	Nitrogen	12-13	glial cell derived neurotrophic factor	Homo sapiens	39-43
17960575-5	2007	Glycopeptides derived from all three N-glycosylation sites of FETUA were observed, and the corresponding CID spectra proved the respective glycans to be oligosaccharides of the triantennary complex type.	Nitrogen	37-38	alpha 2-HS glycoprotein	Homo sapiens	62-67
17960575-8	2007	Disialylated diantennary glycans were observed in glycopeptides of both N-glycosylation sites of TRFE.	Nitrogen	72-73	transferrin	Homo sapiens	97-101
17900180-4	2007	The identification of N-linked glycosylation sites in EGFR and an O-linked glycosylation site in t-PA were also improved through the enhanced identification of the peptide backbone sequence of the glycosylated precursors.	Nitrogen	22-23	epidermal growth factor receptor	Homo sapiens	54-58
17458696-0	2007	Truncations and functional carboxylic acid residues of yeast processing alpha-glucosidase I. Yeast alpha-glucosidase I (Cwh41p) encoded by CWH41 is an endoplasmic reticulum (ER) membrane-bound glycoprotein (833 residues), which plays an important role in the early steps of the N-glycosylation pathway.	Nitrogen	278-279	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	120-126
17458696-0	2007	Truncations and functional carboxylic acid residues of yeast processing alpha-glucosidase I. Yeast alpha-glucosidase I (Cwh41p) encoded by CWH41 is an endoplasmic reticulum (ER) membrane-bound glycoprotein (833 residues), which plays an important role in the early steps of the N-glycosylation pathway.	Nitrogen	278-279	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	139-144
17728248-3	2007	Interactions between nAChR subunits and ERp57 occur via transient intermolecular disulfide bonds and do not require subunit N-linked glycosylation.	Nitrogen	124-125	protein disulfide isomerase family A member 3	Homo sapiens	40-45
17965517-4	2007	N-dealkyation was shown to be catalyzed primarily by CYP3A4.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	53-59
17993143-9	2007	The dissolved inorganic nitrogen (DIN = NH4 + NO2 + NO3) SGD loading estimate of 5.9 x 10(4) mol d(-1) is 1-2 orders of magnitude larger than similar estimates derived from atmospheric deposition and surface water runoff, respectively.	Nitrogen	24-32	NBL1, DAN family BMP antagonist	Homo sapiens	52-55
17661134-1	2007	The N-glycosylation mutants (mnn1 and mnn1 och1) show different morphological characteristics at the restrictive and nonpermissive temperature.	Nitrogen	4-5	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	38-47
17872516-4	2007	Here, new data are presented that confirm post-translational modifications predicted from the BARF1 sequence: phosphorylation on serine and threonine, and N- and O-glycosylation.	Nitrogen	155-156	BaRF1	Human gammaherpesvirus 4	94-99
17923197-1	2007	BACKGROUND/PURPOSE: The release of various enzymes including inducible nitric oxide synthase (iNOS) leads to enterocyte apoptosis through free nitrogen radicals, which in turn leads to impaired mucosal barrier and bacterial translocation with resultant sepsis in necrotizing enterocolitis (NEC).	Nitrogen	143-151	nitric oxide synthase 2	Rattus norvegicus	61-92
17923197-1	2007	BACKGROUND/PURPOSE: The release of various enzymes including inducible nitric oxide synthase (iNOS) leads to enterocyte apoptosis through free nitrogen radicals, which in turn leads to impaired mucosal barrier and bacterial translocation with resultant sepsis in necrotizing enterocolitis (NEC).	Nitrogen	143-151	nitric oxide synthase 2	Rattus norvegicus	94-98
17718551-1	2007	Aldehyde oxidase is a molybdenum hydroxylase that catalyzes the oxidation of aldehydes and nitrogen-containing heterocycles.	Nitrogen	91-99	aldehyde oxidase 1	Homo sapiens	0-16
17640631-0	2007	Inhibition of the mevalonate pathway and activation of p38 MAP kinase are independently regulated by nitrogen-containing bisphosphonates in breast cancer cells.	Nitrogen	101-109	mitogen-activated protein kinase 14	Homo sapiens	55-58
17640631-7	2007	We also show that the nitrogen-containing bisphosphonate-induced effects on p38 phosphorylation occur before accumulation of unprenylated Rap1A or Rac1 activation.	Nitrogen	22-30	mitogen-activated protein kinase 14	Homo sapiens	76-79
17428601-6	2007	In addition to N-formylated peptides, numerous unrelated ligands were recently found to interact with FPR and FPRL1.	Nitrogen	15-16	formyl peptide receptor 1	Homo sapiens	102-105
17705414-3	2007	In each case, the resultant N-linked molecular probes were found to be active in SAPK pathway immunoblot assays, while their O-linked counterparts were inactive.	Nitrogen	28-29	mitogen-activated protein kinase 9	Homo sapiens	81-85
18405112-3	2007	Higher nitrogen fertilization levels significantly influenced the NO3-N concentration in both the runoff and leachate and it was likely to cause adverse environmental impact at the delivery end.	Nitrogen	7-15	NBL1, DAN family BMP antagonist	Homo sapiens	66-69
18062249-6	2007	To characterize the N-glycosylation in the mnn1 och1 mutant, mannoproteins were obtained by hot citrate buffer extraction after the mnn1 och1 cells were crumbled.	Nitrogen	20-21	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	43-52
17707402-9	2007	However, the distinct pattern of mutant Tdp1 activity evident in yeast cells, suggests a more severe defect in Tdp1H(432)N-catalyzed resolution of 3" phospho-adducts.	Nitrogen	121-122	tyrosyl-DNA phosphodiesterase 1	Saccharomyces cerevisiae S288C	40-44
17889671-5	2007	N-glycosylated MUC1-C increases galectin-3 mRNA levels by suppressing expression of the microRNA miR-322 and thereby stabilizing galectin-3 transcripts.	Nitrogen	0-1	microRNA 424	Homo sapiens	97-104
17948780-6	2007	Our estimates for atmospheric nitrogen only include unprocessed atmospheric deposition, i.e., NO3-that is not taken up in watershed soils before being delivered to rivers.	Nitrogen	30-38	NBL1, DAN family BMP antagonist	Homo sapiens	94-97
22444859-9	2007	In conclusion, despite no alteration of intestinal growth, villus hypotrophy associated with a reduction of aminopeptidase nitrogen activity suggest an alteration of the structure of the ileum in early-weaned piglets fed a diet supplying inadequate dietary threonine.	Nitrogen	123-131	carboxypeptidase Q	Homo sapiens	108-122
17661134-1	2007	The N-glycosylation mutants (mnn1 and mnn1 och1) show different morphological characteristics at the restrictive and nonpermissive temperature.	Nitrogen	4-5	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	29-33
17786668-3	2007	In this paper, the SPINMAS technique is evaluated with regard to the determination of 15N abundance and concentration of the most fundamental inorganic nitrogen compounds in ecosystems such as NH4+, NO2-, and NO3-.	Nitrogen	152-160	NBL1, DAN family BMP antagonist	Homo sapiens	209-212
17576805-9	2007	Relative contributions of human CYP1A2, CYP2C19, and CYP3A4 to hepatic diuron N-demethylation, based on average abundances of P450 enzymes in human liver microsomes, were approximately 60, 14, and 13%, respectively.	Nitrogen	78-79	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	53-59
17582597-9	2007	In the "inflammatory" scenario, p53, activated by DNA damage induced by oxygen and nitrogen species, recruits NF-kappaB to activate COX-2, resulting in antiapoptotic effects that contribute to cell expansion in inflammatory precursor lesions.	Nitrogen	83-91	tumor protein p53	Homo sapiens	32-35
17582597-9	2007	In the "inflammatory" scenario, p53, activated by DNA damage induced by oxygen and nitrogen species, recruits NF-kappaB to activate COX-2, resulting in antiapoptotic effects that contribute to cell expansion in inflammatory precursor lesions.	Nitrogen	83-91	prostaglandin-endoperoxide synthase 2	Homo sapiens	132-137
17545692-0	2007	N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins.	Nitrogen	0-1	lipase G, endothelial type	Homo sapiens	26-44
17545692-0	2007	N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins.	Nitrogen	0-1	apolipoprotein E	Homo sapiens	81-85
17545692-0	2007	N-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins.	Nitrogen	0-1	apolipoprotein A1	Homo sapiens	91-97
17576823-8	2007	After treatment by peptide-N-glycosidase F, an enzyme that removes N-glycosylation, FcalphaR from secretory vesicles and tertiary granules revealed a core protein of 32 kDa, which was the same as the backbone of full length of FcalphaR.	Nitrogen	27-28	Fc alpha receptor	Homo sapiens	84-92
17545692-2	2007	EL has five potential N-glycosylation sites, four of which are glycosylated.	Nitrogen	22-23	lipase G, endothelial type	Homo sapiens	0-2
17700863-3	2007	In this report, we compare the global transcript and proteomic profiles of wild-type and Gpa2p deficient diploid yeast strains grown on both rich and nitrogen starved maltose media.	Nitrogen	150-158	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	89-94
17990532-8	2007	In addition, nitrogen in different grain size sediments had also positive correlations with phytoplankton abundance, chlorophyll-a and NO3- concentrations of overlying water.	Nitrogen	13-21	NBL1, DAN family BMP antagonist	Homo sapiens	135-138
17700863-4	2007	We find that deletion of GPA2 results in significantly different transcript and protein profiles when switching from rich to nitrogen starvation media.	Nitrogen	125-133	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	25-29
17924005-6	2007	The potential protein domain analysis of Env sequences showed the loss of a CK-2 phosphorylation site caused by D197N mutation in one epitope, and a N-glycosylation site caused by S246Y and V247I mutations in another epitope.	Nitrogen	116-117	endogenous retrovirus group W member 1, envelope	Homo sapiens	41-44
18516250-2	2007	The present study describes a practical preparation of cysteinyl leukotrienes (leukotriene C(4), D(4) and E(4)) with three (13)C atoms and one (15)N atom in the cysteinyl residue.	Nitrogen	147-148	Rho GDP dissociation inhibitor beta	Homo sapiens	79-110
19090222-0	2007	Intracellular localization of glutamine synthetase in a nitrogen-fixing cyanobacterium Anabaena cylindrical.	Nitrogen	56-64	glutamate-ammonia ligase	Homo sapiens	30-50
18062318-5	2007	Because of the transformation of other forms nitrogen in the process of acid treatment, the NO3(-)-N and NH4(+)-N concentrations in the treated sludge were still high.	Nitrogen	45-53	NBL1, DAN family BMP antagonist	Homo sapiens	92-95
17655222-2	2007	New neutral fac-Re(CO)3L complexes were obtained by treating fac-[Re(CO)3(H2O)3]+ with unsymmetrical tridentate NNN donor ligands (LH) based primarily on a diethylenetriamine (dien) moiety with an aromatic group linked to a terminal nitrogen through a sulfonamide.	Nitrogen	233-241	FA complementation group C	Homo sapiens	12-15
17655222-4	2007	X-ray crystallographic and NMR analyses confirm that in both the solid and the solution states all L- in fac-Re(CO)3L complexes are bound in a tridentate fashion with one donor being nitrogen from a deprotonated sulfonamido group.	Nitrogen	183-191	FA complementation group C	Homo sapiens	105-108
17572094-4	2007	Attenuating the basicity of nitrogen on the side chain, and in particular, introduction of a polar group such as aminomethyl on the distal phenyl ring significantly lowered the hERG activity.	Nitrogen	28-36	ETS transcription factor ERG	Homo sapiens	177-181
19071847-5	2007	During the preconcentration step, Pb(II) was accumulated on the surface of the modifier by the formation of a complex with the nitrogen atoms of the pyridyl groups in the modifier.	Nitrogen	127-135	submaxillary gland androgen regulated protein 3B	Homo sapiens	34-40
17391754-10	2007	Similarly, introducing mutations in STIM1 that prevent the N-linked glycosylation-dependent constitutive expression of the protein in the plasma membrane specifically inhibits the activity of the ARC channels without affecting the CRAC channels.	Nitrogen	59-60	stromal interaction molecule 1	Homo sapiens	36-41
17460031-3	2007	Both t-butyl hydroxylation and N-deethylation reactions were greatly inhibited (&gt;85%) in the presence of CYP3A-selective inhibitory antibodies and chemical inhibitors, indicating that members of the CYP3A subfamily play an important role in TPA023 metabolism.	Nitrogen	31-32	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	108-113
17460031-3	2007	Both t-butyl hydroxylation and N-deethylation reactions were greatly inhibited (&gt;85%) in the presence of CYP3A-selective inhibitory antibodies and chemical inhibitors, indicating that members of the CYP3A subfamily play an important role in TPA023 metabolism.	Nitrogen	31-32	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	202-207
17460031-4	2007	Eadie-Hofstee plots of t-butyl hydroxylation and N-deethylation in pooled CYP3A5-rich human liver microsomes revealed a low K(m) (3.4 and 4.5 microM, respectively) and a high K(m) (12.7 and 40.0 microM, respectively) component.	Nitrogen	49-50	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	74-80
17460031-6	2007	Preincubation of liver microsomes with mifepristone (selectivity for CYP3A4 &gt; CYP3A5) greatly inhibited both t-butyl hydroxylation and N-deethylation (&gt;75%); however, the residual activities were significantly higher in the pooled CYP3A5-rich liver microsomes (p &lt; 0.0005).	Nitrogen	138-139	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	69-75
17460031-6	2007	Preincubation of liver microsomes with mifepristone (selectivity for CYP3A4 &gt; CYP3A5) greatly inhibited both t-butyl hydroxylation and N-deethylation (&gt;75%); however, the residual activities were significantly higher in the pooled CYP3A5-rich liver microsomes (p &lt; 0.0005).	Nitrogen	138-139	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	81-87
17522223-2	2007	Here, we delineate the N-linked glycosylation (N-glycan) sites in gp120 that contribute to optimal DC-SIGN binding.	Nitrogen	23-24	CD209 molecule	Homo sapiens	99-106
17449311-1	2007	Arylalkylamine N-acetyltransferase (AANAT) catalyzes N-acetylation of arylarkylamines.	Nitrogen	15-16	arylalkylamine N-acetyltransferase	Bombyx mori	36-41
17564434-1	2007	The properties of Cu(II) and Co(II) complexes with oxygen- or nitrogen-containing macrocycles have been extensively studied; however, less attention has been paid to the study of complexes containing sulfur atoms in the first coordination sphere.	Nitrogen	62-70	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	29-35
17608466-0	2007	Synthesis and biological evaluation of N-pyrazolyl-N"-alkyl/benzyl/phenylureas: a new class of potent inhibitors of interleukin 8-induced neutrophil chemotaxis.	Nitrogen	51-53	C-X-C motif chemokine ligand 8	Homo sapiens	116-129
17466543-4	2007	The Pklr(G338D) mutation of the CBA/N-Pk(slc) mutant is shown to be more deleterious than the Pklr(I90N) allele with respect to enzymatic activity and severity of hemolytic anemia, with a more dramatic reduction in the half-life of erythrocytes (increased turnover) in the CBA/N-Pk(slc) mice.	Nitrogen	36-37	chemokine (C-C motif) ligand 21A (serine)	Mus musculus	41-44
17466543-4	2007	The Pklr(G338D) mutation of the CBA/N-Pk(slc) mutant is shown to be more deleterious than the Pklr(I90N) allele with respect to enzymatic activity and severity of hemolytic anemia, with a more dramatic reduction in the half-life of erythrocytes (increased turnover) in the CBA/N-Pk(slc) mice.	Nitrogen	36-37	chemokine (C-C motif) ligand 21A (serine)	Mus musculus	282-285
17466543-4	2007	The Pklr(G338D) mutation of the CBA/N-Pk(slc) mutant is shown to be more deleterious than the Pklr(I90N) allele with respect to enzymatic activity and severity of hemolytic anemia, with a more dramatic reduction in the half-life of erythrocytes (increased turnover) in the CBA/N-Pk(slc) mice.	Nitrogen	102-103	chemokine (C-C motif) ligand 21A (serine)	Mus musculus	41-44
17507753-3	2007	In CuL(2) the four N atoms of two bidentate L ligands coordinate the Cu(II) ion in a distorted tetrahedral geometry with Cu-N distances of 1.98 (5)-2.05 (5) A, while two O atoms from two sulfoxide groups complete the distorted octahedral Cu coordination [Cu-O 2.64 (4), 2.74 (4) A].	Nitrogen	19-20	cullin 2	Homo sapiens	3-8
18428410-2	2007	Trf is an N-glycosylated protein with two asparagine glycation sites.	Nitrogen	10-11	transferrin	Homo sapiens	0-3
19704673-1	2007	Nitrate transporters are important for nitrogen acquisition by plants and in algae some require two gene products, NRT2 and NAR2, for function.	Nitrogen	39-47	nitrate transporter 2:1	Arabidopsis thaliana	115-119
17523610-5	2007	To improve the selectivity of these Akt inhibitors over other protein kinases, a nitrogen atom was incorporated into selected phenyl analogues of 7 at the C-6 position of the methyl indazole scaffold.	Nitrogen	81-89	thymoma viral proto-oncogene 1	Mus musculus	36-39
17536794-2	2007	Analogues that feature a fluorescent probe attached through an aliphatic spacer to the central tertiary nitrogen of 1 have high affinity for the hERG channel, and affinity is dependent on both linker length and pendent dye.	Nitrogen	104-112	ETS transcription factor ERG	Homo sapiens	145-149
17451951-5	2007	Synthesis of the analogous cantharidin analogue (19) with incorporation of the amine nitrogen into the heterocycle further increases PP1 (IC(50)=5.9+/-2.2 microM) and PP2A (IC(50)=0.79+/-0.1 microM) inhibition and cell cytotoxicity (GI(50) approximately 3.3 microM).	Nitrogen	85-93	inorganic pyrophosphatase 1	Homo sapiens	133-136
18591993-7	2007	RESULTS: N+S reduced the change in mean proximal percent stenosis (Delta%S) compared to placebo (PL) in subjects with the metabolic syndrome (Delta%Sprox 0.3 vs 3.0, p=0.003) and in the more insulin resistant group of subjects (Delta%Sprox 0.5 vs 2.7, p=0.001), while subjects with dysglycemia (impaired fasting glucose or diabetes) showed a lesser benefit (Delta%Sprox 1 vs 3.2, p=0.13).	Nitrogen	9-10	insulin	Homo sapiens	191-198
26633221-0	2007	Combined QM/MM Molecular Dynamics Study on a Condensed-Phase SN2 Reaction at Nitrogen:  The Effect of Explicitly Including Solvent Polarization.	Nitrogen	77-85	solute carrier family 38 member 5	Homo sapiens	61-64
17396112-6	2007	Chimeras with kidneys of TNF-alpha knockout mice showed significantly less renal dysfunction (blood urea nitrogen, serum creatinine, and glomerular filtration rate), renal histologic injury, and serum TNF-alpha levels; again regardless of the immune cell source.	Nitrogen	105-113	tumor necrosis factor	Mus musculus	25-34
17433262-0	2007	Roles of CYP3A4 and CYP2C19 in methyl hydroxylated and N-oxidized metabolite formation from voriconazole, a new anti-fungal agent, in human liver microsomes.	Nitrogen	55-56	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	9-15
17562881-1	2007	The heart, red skeletal muscles and the nitrogen-fixing legume root nodule function in steady states of high oxygen influx, partial oxygenation of cytoplasmic myoglobin or leghemoglobin and correspondingly low oxygen partial pressure.	Nitrogen	40-48	myoglobin	Equus caballus	159-168
17399990-2	2007	Previous studies showed that the replacement of the aromatic spacer group between nitrogen atoms (N(1) and N(2)) in the P-gp inhibitor XR9576 with ethyl or propyl chain is optimal for P-gp inhibition potency.	Nitrogen	82-90	ATP binding cassette subfamily B member 1	Homo sapiens	120-124
17399990-2	2007	Previous studies showed that the replacement of the aromatic spacer group between nitrogen atoms (N(1) and N(2)) in the P-gp inhibitor XR9576 with ethyl or propyl chain is optimal for P-gp inhibition potency.	Nitrogen	82-90	ATP binding cassette subfamily B member 1	Homo sapiens	184-188
17399990-2	2007	Previous studies showed that the replacement of the aromatic spacer group between nitrogen atoms (N(1) and N(2)) in the P-gp inhibitor XR9576 with ethyl or propyl chain is optimal for P-gp inhibition potency.	Nitrogen	107-111	ATP binding cassette subfamily B member 1	Homo sapiens	120-124
17399990-2	2007	Previous studies showed that the replacement of the aromatic spacer group between nitrogen atoms (N(1) and N(2)) in the P-gp inhibitor XR9576 with ethyl or propyl chain is optimal for P-gp inhibition potency.	Nitrogen	107-111	ATP binding cassette subfamily B member 1	Homo sapiens	184-188
17517749-7	2007	A better understanding of mechanistic processes altering the production and uptake of amino N will help us to improve the overall conversion of dietary N into microbial protein and provide key information needed to further improve mechanistic models describing rumen function and evaluating dietary conditions that influence the efficiency of conversion of dietary N into milk protein.	Nitrogen	92-93	casein kappa	Bos taurus	372-384
17412397-16	2007	The TIN loads at TSP and CJT far exceed 2.5 g N m(-2) yr(-1), which is the N deposition load above which NO3- leaching is expected in temperate and boreal forests.	Nitrogen	6-7	NBL1, DAN family BMP antagonist	Homo sapiens	105-108
17455306-10	2007	The inhibition of N-glycosylation activates ER-specific stress responses in neurons, which include the ER-associated degradation (ERAD) mechanism responsible for differential and extremely efficient degradation of nonglycosylated NR1 by the proteasome after ubiquitination.	Nitrogen	18-19	glutamate ionotropic receptor NMDA type subunit 1	Homo sapiens	230-233
21136710-7	2007	Glycosylation of AQP1 was also investigated using N-glycosidase F, confirming the presence of a N-glycosylated isoform of AQP1 in the 35-45-kDa region.	Nitrogen	50-51	aquaporin 1 (Colton blood group)	Homo sapiens	122-126
17428000-0	2007	Characterization of N-palmitoylated human growth hormone by in situ liquid-liquid extraction and MALDI tandem mass spectrometry.	Nitrogen	20-21	growth hormone 1	Homo sapiens	42-56
17517610-1	2007	The central nitrogen metabolic circuit in enteric bacteria consists of three enzymes: glutamine synthetase, glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	12-20	glutamate-ammonia ligase	Homo sapiens	86-106
17474717-5	2007	However, it was unclear what sites in cytochrome c were prone to Hcy attachment and whether N-linked Hcy can affect the structure and redox function of cytochrome c.	Nitrogen	92-93	cytochrome c, somatic	Homo sapiens	152-164
17472358-0	2007	Novel nitrogen mustard-armed combi-molecules for the selective targeting of epidermal growth factor receptor overexperessing solid tumors: discovery of an unusual structure-activity relationship.	Nitrogen	6-14	epidermal growth factor receptor	Homo sapiens	76-108
17386412-10	2007	Furthermore, we found that CpG-N ODN208 treatment decreased serum TNF-alpha levels in mice injected with sublethal doses of CpG-S ODN whether the CpG-N ODN208 was added prior to or concurrent with the CpG-S ODN.	Nitrogen	31-32	tumor necrosis factor	Mus musculus	66-75
17523816-16	2007	Nitrogen equation of state at pressures up to 30 GPa (300 kbars) and temperatures from the room temperature to 2000 K was obtained using MD simulation results.	Nitrogen	0-8	glycophorin A (MNS blood group)	Homo sapiens	49-52
17523816-17	2007	Results of MD simulations are in very good agreement (the error below 1%) with the experimental data on nitrogen equation of state at pressures below 1 GPa (10 kbars) for temperatures below 1800 K [R. T. Jacobsen et al., J. Phys.	Nitrogen	104-112	glycophorin A (MNS blood group)	Homo sapiens	152-155
17523816-23	2007	These results allow to obtain reliable equation of state of nitrogen for pressures up to 30 GPa (300 kbars), i.e., close to molecular nitrogen stability limit, determined by Nellis et al.	Nitrogen	60-68	glycophorin A (MNS blood group)	Homo sapiens	92-95
17324383-10	2007	In addition, preventing N-glycosylation decreased cell surface Kv1.2 expression levels by approximately 40% primarily by increasing partial endoplasmic reticulum retention and this effect was completely rescued by Kv1.4 subunits, which are glycosylated, but not by cytoplasmic Kvbeta2.1 subunits.	Nitrogen	24-25	potassium voltage-gated channel subfamily A member 2	Homo sapiens	63-68
17494710-0	2007	Differential regulation of endogenous N- and P/Q-type Ca2+ channel inactivation by Ca2+/calmodulin impacts on their ability to support exocytosis in chromaffin cells.	Nitrogen	38-39	calmodulin 1	Homo sapiens	88-98
17350268-3	2007	Among them, a compound (13) possessing a nitrogen at the delta-position of the pyridine ring (delta-N type) showed the most potent affinity for adenosine receptor A(3) subtype, while N-methylation (14) of a pyrrole ring in 13 significantly lowered the potency as adenosine receptor ligands.	Nitrogen	41-49	adenosine A3 receptor	Homo sapiens	144-167
17633169-3	2007	Results showed that the main form of inorganic nitrogen in overlying and interstitial waters of sediments was NO3- -N, accounting for 73.34% and 61.45% respectively.	Nitrogen	47-55	NBL1, DAN family BMP antagonist	Homo sapiens	110-113
17322565-1	2007	We previously identified that four of five putative N-linked glycosylation sites of human endothelial lipase (EL) are utilized and suggested that the substitution of asparagine-116 (Asn-116) with alanine (Ala) (N116A) increased the hydrolytic activity of EL.	Nitrogen	52-53	lipase G, endothelial type	Homo sapiens	90-108
17322565-1	2007	We previously identified that four of five putative N-linked glycosylation sites of human endothelial lipase (EL) are utilized and suggested that the substitution of asparagine-116 (Asn-116) with alanine (Ala) (N116A) increased the hydrolytic activity of EL.	Nitrogen	52-53	lipase G, endothelial type	Homo sapiens	110-112
17322565-6	2007	Finally, we introduced Asn-116 of EL into the analogous positions within LPL and HL, resulting in N-linked glycosylation at this site.	Nitrogen	98-99	lipase G, endothelial type	Homo sapiens	34-36
17322565-8	2007	These data suggest that N-linked glycosylation at Asn-116 reduces the ability of EL to hydrolyze lipids in LDL and HDL2.	Nitrogen	24-25	lipase G, endothelial type	Homo sapiens	81-83
17652830-1	2007	Our previous studies, carried out using rat cDNA-expressed cytochrome P450 (CYP) isoforms, liver microsomes and specific CYP inhibitors, showed that the 1-N- and 3-N-demethylation of caffeine at a therapeutic concentration was predominantly catalyzed by CYP1A2 and CYP2C, its 7-N-demethylation was governed by P450s of the CYP2C subfamily, while its 8-hydroxylation was specifically mediated by CYP1A2.	Nitrogen	46-47	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	59-74
17241121-8	2007	We show that GCPIII lacks dipeptidylpeptidase IV-like activity, its activity is dependent on N-glycosylation, and it is effectively inhibited by several known inhibitors of GCPII.	Nitrogen	93-94	folate hydrolase 1	Homo sapiens	13-18
17652830-1	2007	Our previous studies, carried out using rat cDNA-expressed cytochrome P450 (CYP) isoforms, liver microsomes and specific CYP inhibitors, showed that the 1-N- and 3-N-demethylation of caffeine at a therapeutic concentration was predominantly catalyzed by CYP1A2 and CYP2C, its 7-N-demethylation was governed by P450s of the CYP2C subfamily, while its 8-hydroxylation was specifically mediated by CYP1A2.	Nitrogen	46-47	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	76-79
17371025-9	2007	For the SWNTs where N-R attaches to a parallel bond, the average shift of the sp2 carbons was found to be insensitive to the substituent R. Moreover, the shifts of the functionalized sp3 carbons, as well as of the carbons within the group itself, are independent of the SWNT radius.	Nitrogen	10-11	Sp2 transcription factor	Homo sapiens	78-81
17650853-2	2007	The results indicated that when the dosage was 1.0% of applied N, DMPZP could significantly inhibit the oxidation of soil ammonium, increase soil NH4+ -N concentration, and decrease soil NO3- -N concentration.	Nitrogen	63-64	NBL1, DAN family BMP antagonist	Homo sapiens	187-190
17345583-3	2007	Here, we report that an osm1 frds1 mutant is unable to grow anaerobically, even with glutamate as a sole nitrogen source, when succinate can be produced by the TCA oxidative branch.	Nitrogen	105-113	fumarate reductase	Saccharomyces cerevisiae S288C	24-28
17292967-6	2007	Nitrogen was used as carrier gas at a flow-rate of 2 ml min(-1).	Nitrogen	0-8	CD59 molecule (CD59 blood group)	Homo sapiens	56-62
17220303-5	2007	In this study, we found that Csg1 and Csh1 are N-glycosylated with core-type and mannan-type structures, respectively.	Nitrogen	47-48	mannosylinositol phosphorylceramide synthase catalytic subunit SUR1	Saccharomyces cerevisiae S288C	29-33
17033777-11	2007	Static (15)N NMR spectra of TWD1(335-365) in mechanically aligned lipid bilayers demonstrated that the helical segment of TWD1(335-365) adopts an orientation perpendicular to the membrane normal.	Nitrogen	11-12	FKBP-type peptidyl-prolyl cis-trans isomerase family protein	Arabidopsis thaliana	122-126
17259447-3	2007	N-Demethylation of methadone in vitro is predominantly mediated by cytochrome P450 CYP3A4 and CYP2B6 and somewhat by CYP2C19.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	83-89
17259447-4	2007	This investigation evaluated stereoselectivity, models, and kinetic parameters for methadone N-demethylation by recombinant CYP2B6, CYP3A4, and CYP2C19, and the potential for interactions between enantiomers during racemate metabolism.	Nitrogen	93-94	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	132-138
17205978-0	2007	Rapid and individual-specific glycoprofiling of the low abundance N-glycosylated protein tissue inhibitor of metalloproteinases-1.	Nitrogen	66-67	TIMP metallopeptidase inhibitor 1	Homo sapiens	89-129
17186307-9	2007	We conclude that BGAT is an N-glycosylated protein with two glycoforms and endogenous BGAT synthesis rather than processing is involved in the adaptation to the hyperosmotic stress.	Nitrogen	28-29	solute carrier family 6 member 12	Canis lupus familiaris	17-21
17220303-5	2007	In this study, we found that Csg1 and Csh1 are N-glycosylated with core-type and mannan-type structures, respectively.	Nitrogen	47-48	mannosylinositol phosphorylceramide synthase catalytic subunit CSH1	Saccharomyces cerevisiae S288C	38-42
17258463-4	2007	Incorporation of a nitrogen atom into the phenyl ring at the same position (i.e., 9f) maintained the Akt activity and, in some cases, improved the selectivity over PKA.	Nitrogen	19-27	AKT serine/threonine kinase 1	Homo sapiens	101-104
17450295-6	2007	As a result, the depth to which dissolved anthropogenic N as nitrate (NO3) is leached early in the winter wet season is limited to within the top approximately 130 cm of soil where it accumulates and increases soil acidity.	Nitrogen	56-57	NBL1, DAN family BMP antagonist	Homo sapiens	70-73
17214981-5	2007	Furthermore, excess pyrophosphate-resembling bisphosphonates prevent nitrogen-containing-bisphosphonate-induced accumulation of unprenylated Rap1A, p38 phosphorylation and growth inhibition in human MDA-MB-231 breast cancer and mouse AB-12 mesothelioma cells.	Nitrogen	69-77	mitogen-activated protein kinase 14	Homo sapiens	148-151
17158173-9	2007	A similar specific inhibition of the ARC channels is seen in cells expressing a STIM1 construct in which the N-linked glycosylation sites essential for the constitutive cell surface expression of STIM1, were mutated.	Nitrogen	109-110	stromal interaction molecule 1	Homo sapiens	80-85
17158173-9	2007	A similar specific inhibition of the ARC channels is seen in cells expressing a STIM1 construct in which the N-linked glycosylation sites essential for the constitutive cell surface expression of STIM1, were mutated.	Nitrogen	109-110	stromal interaction molecule 1	Homo sapiens	196-201
17288463-8	2007	On-column APPI LODs (at S/N = 3) were 83, 16, 17, 95, and 7 pg for enantiomer #1, and 104, 23, 19, 122, and 17 pg for enantiomer #2 for benzoin, naringenin, mianserin, mephenesin, and diperodon, respectively, on a Waters ZQ.	Nitrogen	26-27	amyloid beta precursor protein	Homo sapiens	10-14
17082223-1	2007	The aim of this study was to determine the role of N-linked glycosylation in protein stability, intracellular trafficking, and bile acid transport activity of the bile salt export pump [Bsep (ATP-binding cassette B11)].	Nitrogen	51-52	ATP binding cassette subfamily B member 11	Rattus norvegicus	186-190
17360908-9	2007	We conclude that soluble, low-n oligomers of human Abeta trigger synapse loss that can be reversed by therapeutic agents.	Nitrogen	5-6	amyloid beta precursor protein	Homo sapiens	51-56
17126899-3	2007	We investigated the regulatory effect of highly N-acetylated COS (NACOS) on tumor necrosis factor-alpha (TNF-alpha)-induced endothelial cell (EC) E-selectin expression, which is crucial for leukocyte recruitment.	Nitrogen	48-49	tumor necrosis factor	Homo sapiens	76-103
17126899-3	2007	We investigated the regulatory effect of highly N-acetylated COS (NACOS) on tumor necrosis factor-alpha (TNF-alpha)-induced endothelial cell (EC) E-selectin expression, which is crucial for leukocyte recruitment.	Nitrogen	48-49	tumor necrosis factor	Homo sapiens	105-114
16819528-6	2007	Adiponectin was positively related to blood urea nitrogen, a measure of renal function, in men only (P&lt;0.001).	Nitrogen	49-57	adiponectin, C1Q and collagen domain containing	Homo sapiens	0-11
17179073-10	2007	Additionally, either Tsc1/2 or Tor1 are required for growth on a poor nitrogen source such as proline.	Nitrogen	70-78	TSC complex subunit 1	Homo sapiens	21-25
17179073-11	2007	Mutants lacking Tsc1 or Tsc2 are highly sensitive to rapamycin under poor nitrogen conditions, suggesting that the function of Tor1 under such conditions is sensitive to rapamycin.	Nitrogen	74-82	TSC complex subunit 1	Homo sapiens	16-20
17332528-6	2007	In N-43/5 POMC neurons, increasing glucose concentrations decreased phospho-AMPK activity.	Nitrogen	3-4	proopiomelanocortin	Homo sapiens	10-14
17158666-1	2007	Many bacterial species contain multiple copies of the genes that encode the chaperone GroEL and its cochaperone, GroES, including all of the fully sequenced root-nodulating bacteria that interact symbiotically with legumes to generate fixed nitrogen.	Nitrogen	241-249	groEL	Sinorhizobium meliloti	86-91
17158666-1	2007	Many bacterial species contain multiple copies of the genes that encode the chaperone GroEL and its cochaperone, GroES, including all of the fully sequenced root-nodulating bacteria that interact symbiotically with legumes to generate fixed nitrogen.	Nitrogen	241-249	groES	Sinorhizobium meliloti	113-118
17169919-3	2007	When overexpressed in Escherichia coli, AtMGL allowed growth on L-methionine as sole nitrogen source and conferred a high rate of methanethiol emission.	Nitrogen	85-93	methionine gamma-lyase	Arabidopsis thaliana	40-45
17277093-0	2007	A novel ankyrin-repeat membrane protein, IGN1, is required for persistence of nitrogen-fixing symbiosis in root nodules of Lotus japonicus.	Nitrogen	78-86	IGN1	Lotus japonicus	41-45
17264154-1	2007	The mammalian oligosaccharyltransferase (OST) complex is composed of about eight subunits and mediates the N-glycosylation of nascent polypeptide chains entering the endoplasmic reticulum (ER).	Nitrogen	107-108	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	14-39
17264154-1	2007	The mammalian oligosaccharyltransferase (OST) complex is composed of about eight subunits and mediates the N-glycosylation of nascent polypeptide chains entering the endoplasmic reticulum (ER).	Nitrogen	107-108	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	41-44
17264154-6	2007	We propose a new model for OST function where ribophorin I acts as a chaperone or escort to promote the N-glycosylation of selected substrates by the catalytic STT3 subunits.	Nitrogen	104-105	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
17253762-4	2007	The hydrogen bonding between the pyridine nitrogen and the hydroxyl groups of HEMA results in strong intrachain associations, prevents interactions between NREP and CA, and inhibits degradation of CA.	Nitrogen	42-50	neuronal regeneration related protein	Homo sapiens	156-160
17254574-2	2007	Here is shown that the lack of urmylation causes derepression of the GAP1 gene (encoding a nitrogen-regulated broad-spectrum amino acid-scavenging permease) in the presence of rich nitrogen sources, and simultaneous inhibition of the expression of CIT2, a TCA-cycle gene involved in the production of glutamate and glutamine.	Nitrogen	91-99	amino acid permease GAP1	Saccharomyces cerevisiae S288C	69-73
17254574-2	2007	Here is shown that the lack of urmylation causes derepression of the GAP1 gene (encoding a nitrogen-regulated broad-spectrum amino acid-scavenging permease) in the presence of rich nitrogen sources, and simultaneous inhibition of the expression of CIT2, a TCA-cycle gene involved in the production of glutamate and glutamine.	Nitrogen	181-189	amino acid permease GAP1	Saccharomyces cerevisiae S288C	69-73
17157046-7	2007	Interestingly, there were four potential N-glycosylation sites in hamster EC-SOD, whereas there is only one site in other species.	Nitrogen	41-42	superoxide dismutase 3	Homo sapiens	74-80
17217391-11	2007	Urinary creatinine excretion was not affected by E, while body nitrogen loss increased linearly with energy restriction in BT1.	Nitrogen	63-71	adenine nucleotide transporter BT1, chloroplastic/amyloplastic/mitochondrial	Zea mays	123-126
17212815-2	2007	Clinical fasting studies have exhibited a positive correlation between IGF-1 and nitrogen balance during different conditions.	Nitrogen	81-89	insulin like growth factor 1	Homo sapiens	71-76
17189474-1	2007	Rcd-1, a protein highly conserved across eukaryotes, was initially identified as a factor essential for nitrogen starvation-invoked differentiation in fission yeast, and its Saccharomyces cerevisiae homolog, CAF40, has been identified as part of the CCR4-NOT transcription complex, where it interacts with the NOT1 protein.	Nitrogen	104-112	RCD1	Homo sapiens	0-5
17230618-0	2007	Short-term application of low-dose growth hormone in surgical patients: effects on nitrogen balance and blood glucose.	Nitrogen	83-91	growth hormone 1	Homo sapiens	35-49
17230618-10	2007	CONCLUSION: If blood glucose can be controlled, low-dose growth hormone together with hypocaloric nutrition is effective on improving positive nitrogen balance and protein conservation and safe is in postoperative patients.	Nitrogen	143-151	growth hormone 1	Homo sapiens	57-71
17230619-0	2007	Effect of non-anticoagulant N-desulfated heparin on expression of vascular endothelial growth factor, angiogenesis and metastasis of orthotopic implantation of human gastric carcinoma.	Nitrogen	28-29	vascular endothelial growth factor A	Homo sapiens	66-100
17226941-4	2007	The azine- and biphenyl-based beloamphiphiles (Y-Ph-MeC=N-N=CMe-Ph-X and Y-Ph-Ph-X) are ascendants of a new generation of highly anisotropic functional materials with perfect polar order.	Nitrogen	56-57	C-C motif chemokine ligand 28	Homo sapiens	52-55
17352436-2	2007	Their structures and the influence of their ligands (phosphorus and nitrogen atoms directly bonded to the Ga(8) moieties) are discussed on the basis of DFT calculations, providing an insight into a probable mechanism for insertion reactions between GaX and GaX(3) species that lead to a reaction cascade via halides like Ga(2)X(4) and Ga(5)X(7) to Ga(8)X(10) and Ga(8)X(12) (2-), respectively.	Nitrogen	68-76	mesenchyme homeobox 2	Homo sapiens	249-252
16863676-3	2007	Here, we present a modular steady state approach to quantify the network comprising of cAMP-PKA and MAP kinase pathways involved in the regulation of FLO11, a gene which is required for pseudohyphae growth in Saccharomyces cerevisiae under nitrogen starvation.	Nitrogen	240-248	Flo11p	Saccharomyces cerevisiae S288C	150-155
17431866-0	2007	Effects of chain length and N-methylation on a cation-pi interaction in a beta-hairpin peptide.	Nitrogen	28-29	amyloid beta precursor protein	Homo sapiens	72-78
17593875-11	2007	mSOD1 mouse MNs accumulate mitochondria from the axon terminals and generate higher levels of reactive oxygen/nitrogen species than MNs in control mice.	Nitrogen	110-118	superoxide dismutase 1, soluble	Mus musculus	0-5
17089339-1	2007	A new doubly tethered chiral stationary phase (CSP 5) based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid was developed by attaching the second tethering group to silica gel through a carbon atom of the first tethering group of the corresponding singly tethered CSP (CSP 2) containing an N-CH3 tertiary amide linkage, which was previously developed in our laboratory, in order to enhance the CSP stability without the loss of chiral recognition efficiency.	Nitrogen	293-294	DnaJ heat shock protein family (Hsp40) member C5	Homo sapiens	47-50
17470441-8	2007	Data from the NR-null mutant suggest these latter processes may be regulated by downstream nitrogen metabolites.	Nitrogen	91-99	nitrate reductase 1	Arabidopsis thaliana	14-16
17020955-7	2007	In human liver microsomes, involvement of CYP2D6, CYP1A2, CYP2C9, and CYP2C19 in diphenhydramine N-demethylation was confirmed by using P450 isozyme-specific inhibitors.	Nitrogen	97-98	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	42-48
17390656-3	2007	The binding constant KA and n of phthalocyanine aluminium with BSA were determined.	Nitrogen	6-7	albumin	Homo sapiens	63-66
17151328-6	2007	Apical targeting of CX3CL1 was not due to signals that were conferred by its intracellular domain, to associations with lipid rafts, or to O-glycosylation but, rather, depended on N-linked glycosylation of the protein.	Nitrogen	180-181	C-X3-C motif chemokine ligand 1	Homo sapiens	20-26
17727793-2	2007	Bacterial-derived N-formylated peptides, absorbed by the intestinal oligopeptide transporter, hPEPT1, are involved in the pathogenesis of disease-induced intestinal barrier dysfunction, via stimulation of polymorphonuclear leukocyte (PMN) migration.	Nitrogen	18-19	solute carrier family 15 member 1	Homo sapiens	94-100
17932452-1	2007	BACKGROUND AND AIMS: The human epidermal growth factor receptor type 2 (HER-2) seems to be sensitive to nitrogen mustard, because nitrogen mustard heavily alkylates on guanine.	Nitrogen	104-112	erb-b2 receptor tyrosine kinase 2	Homo sapiens	72-77
17932452-1	2007	BACKGROUND AND AIMS: The human epidermal growth factor receptor type 2 (HER-2) seems to be sensitive to nitrogen mustard, because nitrogen mustard heavily alkylates on guanine.	Nitrogen	130-138	erb-b2 receptor tyrosine kinase 2	Homo sapiens	72-77
17932452-2	2007	In this study, we examined the effects of nitrogen mustard on cell growth and expression of HER-2 proteins in cultured human breast cancer cells.	Nitrogen	42-50	erb-b2 receptor tyrosine kinase 2	Homo sapiens	92-97
17396506-0	2007	[Desorption characteristics of inorganic nitrogen in vegetable garden soil and their effects on soil NO3- -N loss potential].	Nitrogen	41-49	NBL1, DAN family BMP antagonist	Homo sapiens	101-104
17085507-7	2007	Disruption of NRT2.2 in Atnrt2.2 reduced IHATS by 19% and this reduction was statistically significant only at 6 h after resupply of nitrate to nitrogen-deprived plants.	Nitrogen	144-152	nitrate transporter 2:1	Arabidopsis thaliana	14-18
17085507-7	2007	Disruption of NRT2.2 in Atnrt2.2 reduced IHATS by 19% and this reduction was statistically significant only at 6 h after resupply of nitrate to nitrogen-deprived plants.	Nitrogen	144-152	nitrate transporter 2:1	Arabidopsis thaliana	24-30
17085507-10	2007	Nevertheless, when maintained on agar containing 0.25 mm KNO(3) as the sole nitrogen source, Atnrt2.1-nrt2.2 consistently exhibited greater stress and growth reduction than Atnrt2.1.	Nitrogen	76-84	nitrate transporter 2:1	Arabidopsis thaliana	93-101
17085507-10	2007	Nevertheless, when maintained on agar containing 0.25 mm KNO(3) as the sole nitrogen source, Atnrt2.1-nrt2.2 consistently exhibited greater stress and growth reduction than Atnrt2.1.	Nitrogen	76-84	nitrate transporter 2:1	Arabidopsis thaliana	95-99
17566265-5	2007	Lectin binding assays have revealed the presence of both O-linked as well as N-linked carbohydrate moieties in human mrt-CD52.	Nitrogen	77-78	CD52 antigen	Mus musculus	121-125
17396506-1	2007	With pot experiment and soil nitrogen desorption model, this paper studied the characteristics of nitrogen desorption in vegetable garden soil, and their effects on the NO3- -N concentration of soil leachate.	Nitrogen	98-106	NBL1, DAN family BMP antagonist	Homo sapiens	169-172
17396506-2	2007	The results showed that soil leachate NO3- -N concentration had a non-linear relationship with the parameters Q, Cli and C1/lamda of soil nitrogen, but the relationship became linear when these eigenvalues were relatively low.	Nitrogen	138-146	NBL1, DAN family BMP antagonist	Homo sapiens	38-41
17168610-2	2006	It was found that for N-protected indoles the reaction proceeded smoothly in the presence of 5 mol % of Pd(acac)2 and 10 mol % of PPh3 at 80 degrees C in HOAc, while for N-unprotected indoles, the reaction was carried out by using 5 mol % of Pd(dba)2 or 2.5 mol % of Pd2(dba)3.CHCl3 with 10 mol % of 2,2"-bipyridine as the catalyst in toluene.	Nitrogen	22-23	caveolin 1	Homo sapiens	130-134
17168610-2	2006	It was found that for N-protected indoles the reaction proceeded smoothly in the presence of 5 mol % of Pd(acac)2 and 10 mol % of PPh3 at 80 degrees C in HOAc, while for N-unprotected indoles, the reaction was carried out by using 5 mol % of Pd(dba)2 or 2.5 mol % of Pd2(dba)3.CHCl3 with 10 mol % of 2,2"-bipyridine as the catalyst in toluene.	Nitrogen	170-171	caveolin 1	Homo sapiens	130-134
16804104-3	2006	Infusion of ANG II in rats for 2 wk led to an elevation in blood pressure and an increase in blood urea nitrogen.	Nitrogen	104-112	angiotensinogen	Rattus norvegicus	12-18
17106110-12	2006	Concentrations of milk urea nitrogen were lower in cows fed DDGS compared with CON (9.36 vs. 10.6 mg/dL).	Nitrogen	28-36	Weaning weight-maternal milk	Bos taurus	18-22
17238830-6	2006	These molecularly defined N-glycosylated IL-24 dimers elicited dose-dependent secretion of tumor necrosis factor-alpha (TNF-alpha) and IL-6 from human monocytes, as well as cytotoxicity to human melanoma cell lines.	Nitrogen	26-27	interleukin 6	Homo sapiens	135-139
17342452-2	2006	By recording (15)N-HSQC-NMR spectra of six different MESD constructs, we could determine a highly structured core region corresponding to residues 104-177.	Nitrogen	17-18	mesoderm development LRP chaperone	Mus musculus	53-57
17238830-6	2006	These molecularly defined N-glycosylated IL-24 dimers elicited dose-dependent secretion of tumor necrosis factor-alpha (TNF-alpha) and IL-6 from human monocytes, as well as cytotoxicity to human melanoma cell lines.	Nitrogen	26-27	tumor necrosis factor	Homo sapiens	91-118
17238830-6	2006	These molecularly defined N-glycosylated IL-24 dimers elicited dose-dependent secretion of tumor necrosis factor-alpha (TNF-alpha) and IL-6 from human monocytes, as well as cytotoxicity to human melanoma cell lines.	Nitrogen	26-27	tumor necrosis factor	Homo sapiens	120-129
17154521-2	2006	Published pharmacophore models of hERG blockers typically contain a basic nitrogen center flanked by aromatic or hydrophobic groups.	Nitrogen	74-82	ETS transcription factor ERG	Homo sapiens	34-38
17095607-6	2006	Nuclear translocation of Gln-3 and Gln-3 reporter activity in pmr1 cells are impaired, but expression of functional Gap1 in the plasma membrane of a pmr1 strain in response to nitrogen limitation is enhanced.	Nitrogen	176-184	amino acid permease GAP1	Saccharomyces cerevisiae S288C	116-120
17095607-6	2006	Nuclear translocation of Gln-3 and Gln-3 reporter activity in pmr1 cells are impaired, but expression of functional Gap1 in the plasma membrane of a pmr1 strain in response to nitrogen limitation is enhanced.	Nitrogen	176-184	Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1	Saccharomyces cerevisiae S288C	149-153
16963451-6	2006	Although the LDLa module of LGR7 was N-glycosylated at position Asn-14, an LGR7 N14Q mutant retained relaxin binding affinity and cAMP signaling, implying that glycosylation is not essential for optimal LDLa function.	Nitrogen	37-38	relaxin/insulin-like family peptide receptor 1	Mus musculus	28-32
17154521-3	2006	However, hERG blockade has been observed in series lacking the basic nitrogen.	Nitrogen	69-77	ETS transcription factor ERG	Homo sapiens	9-13
17023392-0	2006	N-linked glycosylation of IL-13R alpha2 is essential for optimal IL-13 inhibitory activity.	Nitrogen	0-1	interleukin 13	Homo sapiens	26-31
17061958-4	2006	BCAA metabolism provides an important transport system to move nitrogen throughout the body for the synthesis of dispensable (non-essential) amino acids, including the neurotransmitter glutamate in the central nervous system.	Nitrogen	63-71	AT rich interactive domain 4B (RBP1-like)	Mus musculus	0-4
17050697-2	2006	In an attempt to extend the addition of hydride reagents E-H (where E = BR2, AlR2, and SiR3) to the dinitrogen complex ([NPN]Ta)2(mu-H)2(mu-eta1:eta2-N2) [1; where NPN = (PhNSiMe2CH2)2PPh], the reaction with zirconocene chlorohydride, [Cp2Zr(Cl)H]x, was examined.	Nitrogen	100-110	aldo-keto reductase family 1 member B	Homo sapiens	77-81
17010165-6	2006	Viruses with higher V3 charges are more readily transferred to CD4(+) lymphocytes when the V1V2 region is longer and contains an additional N-linked glycosylation site, whereas transfer of viruses with lower V3 charges is greater when the V1V2 region is shorter.	Nitrogen	140-141	CD4 molecule	Homo sapiens	63-66
17023392-8	2006	The N-linked glycosylation of ECD alpha2 was found to be essential for optimal IL-13 inhibitory activity as deglycosylation by PNGase F showed lower activity.	Nitrogen	4-5	interleukin 13	Homo sapiens	79-84
17065392-0	2006	Effects of sub-chronic exposure to naturally occurring N-terminally truncated metabolites of glucose-dependent insulinotrophic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), GIP(3-42) and GLP-1(9-36)amide, on insulin secretion and glucose homeostasis in ob/ob mice.	Nitrogen	55-56	gastric inhibitory polypeptide	Mus musculus	93-138
16877748-10	2006	These results show that the N-glycans that enhance the MIP-2-inducing activity of mouse sICAM-1 are mostly di- and trisialylated complex-type N-glycans including a small fraction carrying more sialic acid residues than antennae and that the nine N-glycosylation sites of mouse sICAM-1 are all glycosylated.	Nitrogen	28-29	chemokine (C-X-C motif) ligand 2	Mus musculus	55-60
17033023-14	2006	Milk urea nitrogen concentration was increased by MO supplementation, but this effect was not apparent when MO was fed in combination with EO (interaction EO x MO).	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
16998085-2	2006	Although NRT2.1 was known to be induced by NO(3)(-) and feedback repressed by reduced nitrogen (N) metabolites, NRT2.1 is surprisingly up-regulated when NO(3)(-) concentration decreases to a low level (&lt;0.5 mm) in media containing a high concentration of NH(4)(+) or Gln (&gt;or=1 mm).	Nitrogen	86-94	nitrate transporter 2:1	Arabidopsis thaliana	9-13
16998085-2	2006	Although NRT2.1 was known to be induced by NO(3)(-) and feedback repressed by reduced nitrogen (N) metabolites, NRT2.1 is surprisingly up-regulated when NO(3)(-) concentration decreases to a low level (&lt;0.5 mm) in media containing a high concentration of NH(4)(+) or Gln (&gt;or=1 mm).	Nitrogen	86-94	nitrate transporter 2:1	Arabidopsis thaliana	9-15
17236593-12	2006	CONCLUSION: The application of low doses of recombinant human growth hormone can improve positive nitrogen balance and reduce the courses of POFS.	Nitrogen	98-106	growth hormone 1	Homo sapiens	62-76
16938287-12	2006	Moreover, this method also allows to counteract the phenotypic drift and to maintain a high-purity selection of SK-N-BE cells expressing beta-arrestin1-GFP.	Nitrogen	115-116	arrestin beta 1	Homo sapiens	137-151
17003472-3	2006	IFN-gamma-deficient (IFN-gamma-/-) mice exhibited higher serum blood urea nitrogen and creatinine levels and exaggerated histopathological changes, compared with WT mice.	Nitrogen	74-82	interferon gamma	Mus musculus	0-9
17003472-3	2006	IFN-gamma-deficient (IFN-gamma-/-) mice exhibited higher serum blood urea nitrogen and creatinine levels and exaggerated histopathological changes, compared with WT mice.	Nitrogen	74-82	interferon gamma	Mus musculus	21-30
16630644-7	2006	The efficiency of PCB-153 decomposition at 350 degrees C for 120 min was approximately 100.0% and 97.1% under air and N(2), respectively.	Nitrogen	118-122	pyruvate carboxylase	Homo sapiens	18-21
17065392-0	2006	Effects of sub-chronic exposure to naturally occurring N-terminally truncated metabolites of glucose-dependent insulinotrophic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), GIP(3-42) and GLP-1(9-36)amide, on insulin secretion and glucose homeostasis in ob/ob mice.	Nitrogen	55-56	gastric inhibitory polypeptide	Mus musculus	140-143
16879711-5	2006	The piglets were submitted to hypoxia (5% O(2); 95% N(2)) over either 1 or 4 h, with recovery periods ranging from 0 to 68 h. Western blot analysis showed that HSP 20 was rapidly induced only in the hippocampus, long before hypoxia-inducible transcription factor HIF-1alpha, while HSP 27 was rapidly induced in the cortex and cerebellum.	Nitrogen	52-53	heat shock protein family B (small) member 6	Homo sapiens	160-166
17022639-4	2006	This way, we demonstrated the presence of five isoforms of apo M in LDL: three that are both N-glycosylated and sialylated, one that is N-glycosylated but not sialylated, and one that is neither N-glycosylated nor sialylated.	Nitrogen	93-94	apolipoprotein M	Homo sapiens	59-64
17022639-4	2006	This way, we demonstrated the presence of five isoforms of apo M in LDL: three that are both N-glycosylated and sialylated, one that is N-glycosylated but not sialylated, and one that is neither N-glycosylated nor sialylated.	Nitrogen	136-137	apolipoprotein M	Homo sapiens	59-64
17022639-4	2006	This way, we demonstrated the presence of five isoforms of apo M in LDL: three that are both N-glycosylated and sialylated, one that is N-glycosylated but not sialylated, and one that is neither N-glycosylated nor sialylated.	Nitrogen	136-137	apolipoprotein M	Homo sapiens	59-64
17022639-5	2006	As judged from the examination of LDL from 20 healthy human subjects, the three N-glycosylated and sialylated forms are most abundant (80-100% of the total apo M in LDL) whereas the unsialylated and unglycosylated variants constitute at most 20%.	Nitrogen	80-81	apolipoprotein M	Homo sapiens	156-161
16885415-1	2006	The general amino acid permease, Gap1p, of Saccharomyces cerevisiae transports all naturally occurring amino acids into yeast cells for use as a nitrogen source.	Nitrogen	145-153	amino acid permease GAP1	Saccharomyces cerevisiae S288C	33-38
17083129-4	2006	We have found that disruption of the genes for either of the yeast 4E-BPs (Eap1p or Caf20p) leads to an inhibition of pseudohyphal growth in the resulting diploid yeast strain following nitrogen limitation.	Nitrogen	186-194	Caf20p	Saccharomyces cerevisiae S288C	84-90
16829530-0	2006	N-glycosylation of fibroblast growth factor receptor 1 regulates ligand and heparan sulfate co-receptor binding.	Nitrogen	0-1	fibroblast growth factor receptor 1	Homo sapiens	19-54
16981714-2	2006	The PTX3 C-terminal domain is required for C1q recognition and complement activation and contains a single N-glycosylation site on Asn 220.	Nitrogen	107-108	pentraxin 3	Homo sapiens	4-8
16981714-4	2006	By specific endo and exoglycosidases digestion and direct mass spectrometric analysis, we found that both recombinant and naturally occurring PTX3 were N-linked to fucosylated and sialylated complex-type sugars.	Nitrogen	152-153	pentraxin 3	Homo sapiens	142-146
16844145-1	2006	Freshly isolated peripheral blood lymphocytes from control rats were found to catalyze the N-demethylation of erythromycin, known to be mediated by cytochrome P450 3A (CYP3A) isoenzymes in rat liver.	Nitrogen	91-92	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	148-166
16844145-1	2006	Freshly isolated peripheral blood lymphocytes from control rats were found to catalyze the N-demethylation of erythromycin, known to be mediated by cytochrome P450 3A (CYP3A) isoenzymes in rat liver.	Nitrogen	91-92	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	168-173
16829530-6	2006	This effect is mediated by N-glycosylation reducing the association rate constant of the receptor for FGF-2 and heparin oligosaccharides.	Nitrogen	27-28	fibroblast growth factor 2	Homo sapiens	102-107
17723675-1	2006	The paper presents a new method for a simultaneous determination of inorganic nitrogen species in the oxidized (NO2-, NO3-) and reduced (NH4+) form in rain water samples.	Nitrogen	78-86	NBL1, DAN family BMP antagonist	Homo sapiens	118-121
16859646-6	2006	Administration of either N-AcGIP, GIP(Lys(37)PAL) or N-AcGIP(Lys(37)PAL) significantly decreased non-fasting plasma glucose and improved glucose tolerance compared to saline treated controls.	Nitrogen	25-26	gastric inhibitory polypeptide	Mus musculus	29-32
16857188-5	2006	GnT-Vb has been shown to perform both N-linked and O-mannosyl-linked glycosylation.	Nitrogen	38-39	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	0-6
16615111-8	2006	UV-visible absorption spectra suggest that three nitrogen donor ligands and one oxygen donor ligand (3N1O) in Abeta(1-16) may form a type II square-planar coordination geometry with Cu2+.	Nitrogen	49-57	amyloid beta precursor protein	Homo sapiens	110-115
16954617-1	2006	In the title compound, [CoCl2(C11H15N3O2)], the CoII ion is five-coordinated in a strongly distorted square-pyramidal arrangement, with one of the two Cl atoms located in the apical position, and the other Cl atom and the three N-donor atoms of the tridentate methyloxime ligand located in the basal plane.	Nitrogen	36-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	48-52
16984125-2	2006	A recombinant Saccharomyces cerevisiae carrying a mutant lysozyme gene encoding the signal sequence of an N-linked glycosylation site at position 49 was cultivated in various pH conditions to investigate the effects of extracellular pH on the glycosylation patterns and the expression of the protein.	Nitrogen	106-107	lysozyme	Homo sapiens	57-65
16395544-3	2006	However, the highest production of CA (380 mg.L(-1)) was obtained when an intermediate concentration of 20 g.L(-1) of SPI (2.95 g.L(-1) total N) was used.	Nitrogen	142-143	chromogranin A	Homo sapiens	118-121
16899515-5	2006	CYP3A4 activity increased by 27% postdialysis (P = 0.002 compared with predialysis) and was significantly inversely related to plasma blood urea nitrogen concentration (rs= -0.50, P = 0.012), but not to several middle molecules.	Nitrogen	145-153	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-6
16961492-3	2006	Anomalies can be defined as NO3(-) derived from nitrogen (N) inputs to the environment from anthropogenic activities, including synthetic fertilizers, livestock waste, and septic effluent.	Nitrogen	48-56	NBL1, DAN family BMP antagonist	Homo sapiens	28-31
16928075-1	2006	Phaeosphaeride A, a nitrogen-containing bicyclic compound produced by an endophytic fungus, inhibits signaling by the transcription factor STAT3.	Nitrogen	20-28	signal transducer and activator of transcription 3	Homo sapiens	139-144
16777347-7	2006	A significant increase in agrin expression was detected in astrocytes cultured in N2 serum-free medium when compared with the ones cultured in serum containing medium.	Nitrogen	82-84	agrin	Rattus norvegicus	26-31
16777347-8	2006	Experiments performed using different components of the N2 mixture indicated that progesterone induced the expression of agrin in astrocytes.	Nitrogen	56-58	agrin	Rattus norvegicus	121-126
16720684-7	2006	The kinetics of N-glucuronidation of FOSA by rat liver microsomes and by hUGT2B4/7 was consistent with a single-enzyme Michaelis-Menten model, whereas human liver microsomes showed sigmoidal kinetics.	Nitrogen	16-17	UDP glucuronosyltransferase family 2 member B4	Homo sapiens	73-82
16757170-4	2006	We have also identified within these diazaspiropiperidine series a key relationship between reducing basicity of the piperidine nitrogen and reducing hERG affinity.	Nitrogen	128-136	ETS transcription factor ERG	Homo sapiens	150-154
16884302-5	2006	While retention of the maleimide ring and pendant 4-phenyl group is necessary for potency, replacement of the carbazole nitrogen by oxygen is well tolerated and results in improved Wee1 selectivity against the related checkpoint kinase Chk1.	Nitrogen	120-128	checkpoint kinase 1	Homo sapiens	236-240
16884302-6	2006	Wee1 potency and selectivity are also enhanced by the incorporation of lipophilic functionality at the 2"-position of the 4-phenyl ring, and Wee1 selectivity against Chk1 is favored by C3-C5 alkyl substitution of the carbazole nitrogen.	Nitrogen	227-235	checkpoint kinase 1	Homo sapiens	166-170
17723624-5	2006	The detailed spectral information in the one-phonon region of diamonds with high nitrogen impurities can be clearly observed in the ATR spectra but those in the diffuse reflectance and transflectance spectra were obscured by the saturated absorption.	Nitrogen	81-89	ATR serine/threonine kinase	Homo sapiens	132-135
16880608-9	2006	These results suggest that N-linked glycosylation on Dectin-1 is essential for the recognition of fungal beta-glucan and subsequent activation of NF-kappaB.	Nitrogen	27-28	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	146-155
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	72-73	UDP glucuronosyltransferase family 2 member B4	Homo sapiens	129-136
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	162-163	UDP glucuronosyltransferase family 2 member B4	Homo sapiens	129-136
16443618-6	2006	XPS analysis shows that the fibronectin-immobilized PLA surface is enriched with nitrogen atoms.	Nitrogen	81-89	fibronectin 1	Homo sapiens	28-39
16488441-8	2006	In male patients, among the various blood biochemical parameters, serum lactate dehydrogenase, and blood urea nitrogen levels were positively correlated with serum VEGF levels.	Nitrogen	110-118	vascular endothelial growth factor A	Homo sapiens	164-168
16584890-3	2006	In this report, we describe a cost-effective expression system in Escherichia coli for the production of ET-1 enriched with (15)N and (13)C isotopes.	Nitrogen	128-129	endothelin 1	Homo sapiens	105-109
16766089-2	2006	Among the compounds presented herein, (R)-pyrrolidine-2-acetic acid (R)-4d substituted with a 2-[tris(4-methoxyphenyl)methoxy]ethyl residue at the nitrogen atom showed the highest affinity at GAT-3 (IC(50) = 3.1 microM) comparable with the well-known GAT-3 blocker (S)-SNAP-5114.	Nitrogen	147-155	solute carrier family 6 member 13	Homo sapiens	192-197
16766089-2	2006	Among the compounds presented herein, (R)-pyrrolidine-2-acetic acid (R)-4d substituted with a 2-[tris(4-methoxyphenyl)methoxy]ethyl residue at the nitrogen atom showed the highest affinity at GAT-3 (IC(50) = 3.1 microM) comparable with the well-known GAT-3 blocker (S)-SNAP-5114.	Nitrogen	147-155	solute carrier family 6 member 13	Homo sapiens	251-256
16879428-0	2006	Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term.	Nitrogen	122-130	solute carrier family 6 member 1	Homo sapiens	62-66
16879428-2	2006	Under nitrogen limitation or rapamycin treatment, NCR genes are activated by Gln3 or Gat1, or by both factors.	Nitrogen	6-14	solute carrier family 6 member 1	Homo sapiens	85-89
16840630-12	2006	Milk urea nitrogen was similar for cows fed control and DG but greater for cows fed WDGS than DDGS and tended to be higher for cows fed 20% DG than 10% DG.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
16793534-5	2006	Various AGE inhibitors have been developed in recent years, and their underlying mechanism is based on the attenuation of glycoxidation and/or oxidative stress by the sequestration of metal ions, reactive 1,2-dicarbonyl compounds, and reactive oxygen and reactive nitrogen species.	Nitrogen	264-272	renin binding protein	Homo sapiens	8-11
16484342-8	2006	Finally, FUT1 and FUT2 were both found to direct alpha2-fucosylation on type 1 chains on both N- and O-linked structures.	Nitrogen	94-95	fucosyltransferase 2	Homo sapiens	18-22
16632354-1	2006	Based on an existing series of 5-HT2A receptor ligands containing a basic nitrogen, we designed a non-basic lead that had reduced affinity for both the 5-HT2A receptor and the IKr potassium channel.	Nitrogen	74-82	5-hydroxytryptamine receptor 2A	Homo sapiens	31-46
16749908-8	2006	These studies demonstrate that inhibition of the endogenous N/OFQ system may represent a new therapeutic target for prevention of neuronal loss associated with PD.	Nitrogen	60-61	prepronociceptin	Homo sapiens	62-65
16765486-2	2006	iNOS has been found to be a major contributor to initiation/exacerbation of the central nervous system (CNS) inflammatory/degenerative conditions through the production of excessive NO which generates reactive nitrogen species (RNSs).	Nitrogen	210-218	nitric oxide synthase 2	Homo sapiens	0-4
16824075-10	2006	Rats treated with L-NAME had significantly higher plasma levels of total bilirubin, ALT, creatinine and TNF- alpha as compared with rats treated with L-canavanine or N/S (P &lt; 0.01).	Nitrogen	20-21	tumor necrosis factor	Rattus norvegicus	104-114
16897491-1	2006	Here, a hemoglobin gene from the nitrogen-fixing actinorhizal plant Myrica gale was isolated, cloned and sequenced.	Nitrogen	33-41	hemoglobin 2	Arabidopsis thaliana	8-18
16632354-1	2006	Based on an existing series of 5-HT2A receptor ligands containing a basic nitrogen, we designed a non-basic lead that had reduced affinity for both the 5-HT2A receptor and the IKr potassium channel.	Nitrogen	74-82	5-hydroxytryptamine receptor 2A	Homo sapiens	152-167
16632354-3	2006	This work has shown that the proposed pharmacophore model for the 5-HT2A receptor which suggests that a basic nitrogen is required for the binding of ligands is questionable.	Nitrogen	110-118	5-hydroxytryptamine receptor 2A	Homo sapiens	66-81
16752921-8	2006	The human E-NTPDase 8 has similar topology as the avian and mouse E-NTPDase 8 but has fewer potential N-glycosylation sites and only two amino acid residues in the cytoplasm at its C-terminus.	Nitrogen	12-13	ectonucleoside triphosphate diphosphohydrolase 8	Mus musculus	66-77
16700091-0	2006	Car-Parrinello molecular dynamics study of the blue-shifted F3CH...FCD3 system in liquid N2.	Nitrogen	89-91	FECD5	Homo sapiens	67-71
16601122-7	2006	These interactions were verified in GST-pull down assays in which human SHBG bound the carboxyl-terminal domains of fibulin-1D and fibulin-2 in a steroid-dependent manner, with estradiol being the most effective ligand, and were enhanced by reducing the N-glycosylation of human SHBG.	Nitrogen	254-255	sex hormone binding globulin	Homo sapiens	72-76
16700091-2	2006	A Car-Parrinello molecular dynamics simulation was performed for a complex formed by fluoroform (F3CH) and deuterated methyl fluoride (FCD3) in liquid nitrogen.	Nitrogen	151-159	FECD5	Homo sapiens	135-139
16458519-5	2006	Using a CYP26A1 homology model (based on CYP3A4) template, docking experiments were performed with MOE with multiple hydrophobic interactions observed in addition to coordination between the triazole nitrogen and the haem transition metal.	Nitrogen	200-208	cytochrome P450 family 26 subfamily A member 1	Homo sapiens	8-15
16709188-8	2006	The binding site encompasses an N-acetylated glucosamine-rich domain separating two highly sulphated sequences that each binds to one IFNgamma monomer.	Nitrogen	32-33	interferon gamma	Homo sapiens	134-142
16458519-5	2006	Using a CYP26A1 homology model (based on CYP3A4) template, docking experiments were performed with MOE with multiple hydrophobic interactions observed in addition to coordination between the triazole nitrogen and the haem transition metal.	Nitrogen	200-208	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	41-47
16845446-4	2006	When the cells were treated with hypoxia (5% CO2, 95% N2), IL-8 secretion increased from 0.29 +/- 0.04 to 2.59 +/- 0.42 ng/ml.	Nitrogen	54-56	C-X-C motif chemokine ligand 8	Homo sapiens	59-63
16892401-6	2006	Unexpectedly, F substitution next to the nitrogen center reduced the lipophilicity of the ligands, as revealed by measurements of the logarithmic partition coefficient log D. The biological assays showed that all compounds are thrombin inhibitors with activities between Ki=0.08 and 2.17 microM.	Nitrogen	41-49	coagulation factor II, thrombin	Homo sapiens	227-235
16510538-10	2006	These findings demonstrated that the N-alkylPP adduct was produced via metabolism of DASO2 in murine liver and lung microsomes, in human liver microsomes, in recombinant CYP2E1, and in vivo in murine liver.	Nitrogen	37-38	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	170-176
16289048-6	2006	Comparison of cat myocilin to human myocilin shows a 87% similarity, including conservation of the N-terminal leucine zipper, N-linked glycosylation site, C-terminal olfactomedin domain, and all five cysteine residues thought to be involved in disulfide bond formation.	Nitrogen	99-100	myocilin	Homo sapiens	18-26
16289048-6	2006	Comparison of cat myocilin to human myocilin shows a 87% similarity, including conservation of the N-terminal leucine zipper, N-linked glycosylation site, C-terminal olfactomedin domain, and all five cysteine residues thought to be involved in disulfide bond formation.	Nitrogen	99-100	myocilin	Homo sapiens	36-44
16624901-4	2006	In this study we analyzed the gene expression profile on a genomewide scale and found that deletion of either tsc1(+) or tsc2(+) affects gene induction upon nitrogen starvation.	Nitrogen	157-165	TSC complex subunit 1	Homo sapiens	110-114
25580068-0	2006	A 0.6 T/650 mm RT Bore Solid Nitrogen Cooled MgB2 Demonstration Coil for MRI-a Status Report.	Nitrogen	29-37	secretoglobin family 2A member 1	Homo sapiens	45-49
16702334-1	2006	Nitrogen (N) and sulfur (S) coexist in the biosphere as free elements or in the form of simple inorganic NO3- and SO4(2-) oxyanions, which must be reduced before undergoing anabolic processes leading to the production of methionine (Met) and other S-containing molecules.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	105-108
16571673-11	2006	Therefore, our work demonstrates that AEX-3 regulates both RAB-3 and RAB-27, that both RAB-3 and RAB-27 regulate synaptic transmission, and that RAB-27 potentially acts through its effector RBF-1 to promote soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) function.	Nitrogen	215-216	Rabphilin-1	Caenorhabditis elegans	190-195
16640345-1	2006	A series of N-substituted cage dimeric 1,4-dihydropyridines 3a-e was evaluated as inhibitors of membrane efflux pump P-glycoprotein (P-gp) in multidrug resistant (mdr) cancer cells.	Nitrogen	12-13	ATP binding cassette subfamily B member 1	Homo sapiens	117-131
16622833-2	2006	The three N-glycosylation sites of A1PI contain diantennary N-glycans but also triantennary and even traces of tetraantennary structures leading to the typical IEF pattern observed for A1PI.	Nitrogen	10-11	serpin family A member 1	Homo sapiens	35-39
16622833-2	2006	The three N-glycosylation sites of A1PI contain diantennary N-glycans but also triantennary and even traces of tetraantennary structures leading to the typical IEF pattern observed for A1PI.	Nitrogen	10-11	serpin family A member 1	Homo sapiens	185-189
16964949-4	2006	The nitrogen flux by wet deposition in the six years was 58.1 kg x hm(-2) x yr(-1), among which, NO3 (-) -N accounted for 54%.	Nitrogen	4-12	NBL1, DAN family BMP antagonist	Homo sapiens	97-100
16964949-2	2006	The results showed that in the six years, the nitrogen content in the rainwater was rather high, with an average concentration of NO3 (-) -N and NH4 (+) -N being 2.59 mg x L(-1) and 2.16 mg x L(-1), respectively, and a total inorganic nitrogen of 4.74 mg x L(-1), which exceeded the water eutrophication level (0.2 mg x L(-1)).	Nitrogen	46-54	NBL1, DAN family BMP antagonist	Homo sapiens	130-133
16964949-2	2006	The results showed that in the six years, the nitrogen content in the rainwater was rather high, with an average concentration of NO3 (-) -N and NH4 (+) -N being 2.59 mg x L(-1) and 2.16 mg x L(-1), respectively, and a total inorganic nitrogen of 4.74 mg x L(-1), which exceeded the water eutrophication level (0.2 mg x L(-1)).	Nitrogen	134-140	NBL1, DAN family BMP antagonist	Homo sapiens	130-133
16700545-2	2006	The CYP3A4 isoform is inhibited by antifungal imidazoles or triazoles, which form low-spin heme iron complexes via formation of a nitrogen-ferric iron coordinate bond.	Nitrogen	130-138	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	4-10
16700545-3	2006	However, CYP3A4 also slowly oxidizes the antifungal itraconazole (ITZ) at a site that is approximately 25 A from the triazole nitrogens, suggesting that large antifungal azoles can adopt multiple orientations within the CYP3A4 active site.	Nitrogen	126-135	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	9-15
16676969-6	2006	IR spectral changes show that, upon further warming to 200 K, 2 isomerizes into the N-bonded nitro linkage isomer Mn(Por)(NO)(NO2) (3).	Nitrogen	84-85	cytochrome p450 oxidoreductase	Homo sapiens	117-120
16640345-1	2006	A series of N-substituted cage dimeric 1,4-dihydropyridines 3a-e was evaluated as inhibitors of membrane efflux pump P-glycoprotein (P-gp) in multidrug resistant (mdr) cancer cells.	Nitrogen	12-13	ATP binding cassette subfamily B member 1	Homo sapiens	133-137
16368738-0	2006	Functional influence of N-glycosylation in OCT2-mediated tetraethylammonium transport.	Nitrogen	24-25	solute carrier family 22 member 2	Oryctolagus cuniculus	43-47
16291577-2	2006	Because the NKCC2 sequence contains two putative N-linked glycosylation sites, one of which is conserved with the renal Na(+)-Cl(-) cotransporter in which glycosylation affects thiazide affinity, we assessed the role of glycosylation on NKCC2 functional properties.	Nitrogen	12-13	solute carrier family 12 member 1 L homeolog	Xenopus laevis	237-242
16368738-1	2006	OCT2, an organic cation transporter critical for removal of many drugs and toxins from the body, contains consensus sites for N-glycosylation at amino acid position 71, 96, and 112.	Nitrogen	126-127	solute carrier family 22 member 2	Oryctolagus cuniculus	0-4
16368738-3	2006	To address these issues, the acquisition of N-glycosylation was disrupted by mutating the amino acid asparagine (N) to glutamine (Q) at these sites in the rabbit ortholog of OCT2, which was expressed in Chinese hamster ovary cells.	Nitrogen	44-45	solute carrier family 22 member 2	Oryctolagus cuniculus	174-178
16634581-13	2006	The coordination environment around the bridging Co(II) ion contains four oxygen (two P-O units, one chelating nitrate) and two nitrogen atoms (pyridyloxy nitrogens).	Nitrogen	128-136	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	49-55
16449350-4	2006	The N(497) glycosylation site of the c-peptide chain is evolutionary conserved among LAMANs and is very important for the maintenance of the lysosomal stability of the enzyme.	Nitrogen	4-5	insulin	Homo sapiens	37-46
16634581-13	2006	The coordination environment around the bridging Co(II) ion contains four oxygen (two P-O units, one chelating nitrate) and two nitrogen atoms (pyridyloxy nitrogens).	Nitrogen	155-164	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	49-55
16672605-1	2006	Among the rhizobia that establish nitrogen-fixing nodules on the roots of host plants, many contain multiple copies of genes encoding the sigma factor RpoH and the chaperone GroEL/GroES.	Nitrogen	34-42	groEL	Sinorhizobium meliloti	174-179
16672605-1	2006	Among the rhizobia that establish nitrogen-fixing nodules on the roots of host plants, many contain multiple copies of genes encoding the sigma factor RpoH and the chaperone GroEL/GroES.	Nitrogen	34-42	groES	Sinorhizobium meliloti	180-185
16510126-5	2006	The apparent Km value of CYP2D6 was close to that for 5-MeO-DIPT O-demethylation, and the Km values of other CYP enzymes were similar to those of the low-Km (CYP2C19), intermediate-Km (CYP1A2, CYP2C8 and CYP3A4) and high-Km phases (CYP2C9), respectively, for N-deisopropylation in human liver microsomes.	Nitrogen	259-260	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	25-31
16673766-12	2006	It can be concluded that the ingestion of IP6 reduces the digestibility coefficients of amino acids and the metabolizability of nitrogen of casein.	Nitrogen	128-136	G protein regulated inducer of neurite outgrowth 2	Gallus gallus	42-45
16755913-6	2006	The mutant of wild type human PRNP gene at N-glycosylation modification sites and six modified mutants with mono- or non-N-glycosylation had been obtained successfully in the study.	Nitrogen	43-44	prion protein	Homo sapiens	30-34
16513638-8	2006	Treatment with tunicamycin, an inhibitor of N-linked glycosylation, induced the appearance of the unglycosylated 115-kDa CaR form, which was further increased by exposure to MG132, or upon transfection with a dorfin dominant negative construct, suggesting that dorfin-mediated proteasomal degradation of immature CaR occurs from the endoplasmic reticulum.	Nitrogen	44-45	calcium sensing receptor	Homo sapiens	121-124
16415110-6	2006	Despite these differences in metabolism, all four ITZ stereoisomers induced a type II binding spectrum with CYP3A4, characteristic of coordination of the triazole nitrogen to the heme iron (K(s) 2.2-10.6 nM).	Nitrogen	163-171	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	108-114
16475181-6	2006	The lesser followed competitive channel is the 1,3-H-shift from C to N atom along with N-O1 bond rupture of b(1) to form P(3) (CCl(2)O + HNO).	Nitrogen	69-70	exosome component 10	Homo sapiens	121-125
16585613-8	2006	Similarly, N2O and CH4 fluxes were predominantly controlled by NO3- content and labile C and N availability in both ST and NT soils at field moisture content, and NH4+ content after irrigation.	Nitrogen	11-12	NBL1, DAN family BMP antagonist	Homo sapiens	63-66
16571816-0	2006	Influence of N-linked glycosylation of porcine reproductive and respiratory syndrome virus GP5 on virus infectivity, antigenicity, and ability to induce neutralizing antibodies.	Nitrogen	13-14	glycoprotein V platelet	Homo sapiens	91-94
16541468-8	2006	In situ mutagenesis experiments confirmed the necessity of N-linked glycosylation for efficient sorting of TNF-alpha into rodent mast cell granules.	Nitrogen	59-60	tumor necrosis factor	Homo sapiens	107-116
16571816-2	2006	Three putative N-linked glycosylation sites (N34, N44, and N51) are located on the GP5 ectodomain, where a major neutralization epitope also exists.	Nitrogen	15-16	glycoprotein V platelet	Homo sapiens	83-86
16407296-4	2006	Wnt13A, a typical Wnt, is N-glycosylated and localized in the endoplasmic reticulum, with only a small fraction being secreted.	Nitrogen	26-27	Wnt family member 2B	Homo sapiens	0-3
16763901-1	2006	Glutamine synthetase (GS) is ubiquitously expressed in human tissues, being involved in ammonia detoxification and interorgan nitrogen flux.	Nitrogen	126-134	glutamate-ammonia ligase	Homo sapiens	0-20
16763901-1	2006	Glutamine synthetase (GS) is ubiquitously expressed in human tissues, being involved in ammonia detoxification and interorgan nitrogen flux.	Nitrogen	126-134	glutamate-ammonia ligase	Homo sapiens	22-24
16407254-7	2006	Here we employ a full-length form of Rsb1p and find that this protein is localized to the plasma membrane and is modified by N-linked glycosylation.	Nitrogen	125-126	phospholipid-translocating ATPase RSB1	Saccharomyces cerevisiae S288C	37-42
16289855-1	2006	Tetracyclic nitrogen bridgehead compounds, dibenzodiazecines and tricyclic quinazolinimines, in which the size of the alicyclic ring system and the length of the alkyl chain between the quinazolinimine moiety and a phenyl ring connected to the imine nitrogen atom were changed systematically, were synthesized and their ability to inhibit acetyl- and butyrylcholinesterase (AChE/BChE), respectively, was evaluated.	Nitrogen	12-20	acetylcholinesterase (Cartwright blood group)	Homo sapiens	374-378
16526788-2	2006	BF2 complexes with only one pyrrole NH interaction site (2d,e), which exhibit smaller affinities than the basic structure (2b), bind anions tightly, which is inferred by UV/vis absorption spectral changes, compared to the derivatives with an alkyl group at the bridging carbon (2f) or two pyrrole nitrogen sites (2c).	Nitrogen	297-305	forkhead box G1	Homo sapiens	0-3
16213030-2	2006	Using bioinformatics and molecular cloning techniques, we isolated a bovine gene that encodes a polypeptide of 206 amino acids with structural features shared by mouse and human dectin-2, including a high homology with mouse dectin-2 (66%), a type II configuration, a short cytoplasmic domain without tyrosine-based signal motifs, a carbohydrate recognition domain, a putative N-glycosylation site, and an EPN motif involved in the Ca(2+)-dependent binding of hexose carbohydrates.	Nitrogen	377-378	C-type lectin domain family 4, member n	Mus musculus	225-233
16574426-3	2006	ATP-depletion or inhibition of N-glycosylation was found to cause IFN-gamma to accumulate into detergent-insoluble aggregates in the ER.	Nitrogen	31-32	interferon gamma	Homo sapiens	66-75
27265228-6	2006	We found a negative correlation between TGF and C-reactive protein and blood urea nitrogen and a positive correlation between TGF and hemoglobin level in newly diagnosed patients.	Nitrogen	82-90	C-reactive protein	Homo sapiens	48-66
16272405-3	2006	The results indicate that CYP1A2 and CYP3A4 are the main enzymes responsible for 5-sulfoxidation and N-demethylation (34-52%), whereas CYP2D6 is the basic enzyme that catalyzes mono-2- and di-2-sulfoxidation of thioridazine in human liver (49 and 64%, respectively).	Nitrogen	101-102	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	37-43
16427819-1	2006	The Saccharomyces cerevisiae protein Ure2 functions as a regulator of nitrogen metabolism and as a glutathione-dependent peroxidase.	Nitrogen	70-78	glutathione peroxidase	Saccharomyces cerevisiae S288C	37-41
16272405-3	2006	The results indicate that CYP1A2 and CYP3A4 are the main enzymes responsible for 5-sulfoxidation and N-demethylation (34-52%), whereas CYP2D6 is the basic enzyme that catalyzes mono-2- and di-2-sulfoxidation of thioridazine in human liver (49 and 64%, respectively).	Nitrogen	101-102	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	135-141
16306051-3	2006	By examining mutants of mST3Gal-V, in which each asparagine was replaced with glutamine (N180Q, N224Q, N334Q), we determined that all three sites are N-glycosylated and that each N-glycan is required for enzyme activity.	Nitrogen	89-90	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	24-33
16306051-4	2006	Despite their importance, N-glycosylation sites in ST3Gal-V are not conserved among species.	Nitrogen	26-27	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	51-59
16566573-9	2006	The results suggested that TNF-alpha can activate the 26S proteasome system in skeletal muscle, thus enhancing the degradation of protein, which is associated with the development of negative nitrogen balance after scald.	Nitrogen	192-200	tumor necrosis factor	Mus musculus	27-36
16792896-7	2006	Seven potential N-linked glycosylation sites in the HA1 regions located at amino acid positions 8, 22, 38, 63, 126, 165 and 285 were conserved in all the viruses analyzed.	Nitrogen	16-17	Rho GTPase activating protein 45	Homo sapiens	52-55
16111903-2	2006	Nitrogen-derived reactive oxidant species capable of involving DNA single strand breakage and PARP activation include peroxynitrite (the reaction product of nitric oxide and superoxide), but not nitric oxide per se.	Nitrogen	0-8	poly(ADP-ribose) polymerase 1	Homo sapiens	94-98
16415211-0	2006	A central role for the nitrate transporter NRT2.1 in the integrated morphological and physiological responses of the root system to nitrogen limitation in Arabidopsis.	Nitrogen	132-140	nitrate transporter 2:1	Arabidopsis thaliana	43-47
16415211-2	2006	Up-regulation of the NO(3)(-) HATS by nitrogen starvation is suppressed in the atnrt2.1-1 mutant of Arabidopsis (Arabidopsis thaliana), deleted for both NRT2.1 and NRT2.2 nitrate transporter genes.	Nitrogen	38-46	nitrate transporter 2:1	Arabidopsis thaliana	153-159
16415211-2	2006	Up-regulation of the NO(3)(-) HATS by nitrogen starvation is suppressed in the atnrt2.1-1 mutant of Arabidopsis (Arabidopsis thaliana), deleted for both NRT2.1 and NRT2.2 nitrate transporter genes.	Nitrogen	38-46	nitrate transporter 2:1	Arabidopsis thaliana	153-157
16415211-10	2006	However, the mutation of NRT2.1 was also found to inhibit initiation of LR primordia in plants subjected to nitrogen limitation independently of the rate of NO(3)(-) uptake by the whole root system and even of the presence of added NO(3)(-) in the external medium.	Nitrogen	108-116	nitrate transporter 2:1	Arabidopsis thaliana	25-31
16415211-12	2006	Thus, it is concluded that NRT2.1 has a key dual function in coordinating root development with external NO(3)(-) availability, both indirectly through its role as a major NO(3)(-) uptake system that determines the nitrogen uptake-dependent RSA responses, and directly through a specific action on LR initiation under nitrogen-limited conditions.	Nitrogen	215-223	nitrate transporter 2:1	Arabidopsis thaliana	27-33
16415211-12	2006	Thus, it is concluded that NRT2.1 has a key dual function in coordinating root development with external NO(3)(-) availability, both indirectly through its role as a major NO(3)(-) uptake system that determines the nitrogen uptake-dependent RSA responses, and directly through a specific action on LR initiation under nitrogen-limited conditions.	Nitrogen	318-326	nitrate transporter 2:1	Arabidopsis thaliana	27-33
16438547-3	2006	The MP2/6-31G(d) geometries and a natural population analysis of natural lone-pair orbitals on the donor atoms support the mechanism and reveal that oxygen and nitrogen donor groups are more stabilizing than sulfur.	Nitrogen	160-168	major intrinsic protein of lens fiber	Homo sapiens	4-9
16337230-1	2006	In Saccharomyces cerevisiae, signal transduction through pathways governing mating, osmoregulation, and nitrogen starvation depends upon a direct interaction between the sterile alpha motif (SAM) domains of the Ste11 mitogen-activated protein kinase kinase kinase (MAPKKK) and its regulator Ste50.	Nitrogen	104-112	Ste50p	Saccharomyces cerevisiae S288C	291-296
16465322-1	2006	Selective electrocatalytic hydrogenation of NO3- to N2 in water has successfully been achieved at room temperature using a membrane-electrode assembly (MEA) consisting of an H+ -conducting solid polymer electrolyte (Nafion-117) and a surface-modified Pt cathode.	Nitrogen	52-54	NBL1, DAN family BMP antagonist	Homo sapiens	44-47
16361248-6	2006	The association required N-linked glycosylation of hERG channels.	Nitrogen	25-26	ETS transcription factor ERG	Homo sapiens	51-55
16469141-2	2006	We studied whether n-3 long-chain PUFA could prevent insulin resistance induced by dexamethasone (a glucocorticoid) in healthy human volunteers.	Nitrogen	19-20	insulin	Homo sapiens	53-60
16489927-4	2006	Key intermediates of nitrogen metabolism (glutamate, glutamine, and aspartate) are involved in the regulation of NADP-IDH and AsAT.	Nitrogen	21-29	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	126-130
16489927-6	2006	Obviously, carbon and nitrogen metabolism in the rat liver can be controlled through redistribution of 2-oxoglutarate between different metabolic processes via regulatory mechanisms influencing differently located forms of NADP-IDH and AsAT.	Nitrogen	22-30	glutamic-oxaloacetic transaminase 2	Rattus norvegicus	236-240
16415006-5	2006	The presence of a single N-linked glycosylation site on either the prM or E glycoprotein of WNV was sufficient to allow DC-SIGNR-mediated infection, demonstrating that uncleaved prM protein present on a flavivirus virion can influence viral tropism under certain circumstances.	Nitrogen	25-26	C-type lectin domain family 4 member M	Homo sapiens	120-128
16432914-7	2006	A computer-assisted simulation study using energy minimization and molecular dynamics techniques indicated that the hydrophobic interaction of an aromatic moiety of the substrate with Phe-120 and the ionic interaction of a basic nitrogen atom of the substrate with Glu-222 in combination with Glu-216 play important roles in the binding of BF and BTL by CYP2D6 and the orientation of these substrates in the active-site cavity.	Nitrogen	229-237	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	354-360
16401094-1	2006	Universal mechanisms of adsorption and capillary condensation of toluene and nitrogen on ordered MCM-41 and PHTS materials are studied by means of high-resolution experiments and Monte Carlo molecular simulations.	Nitrogen	77-85	LY6/PLAUR domain containing 1	Homo sapiens	108-112
16407450-0	2006	Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.	Nitrogen	115-123	glutamine synthetase	Nicotiana tabacum	0-20
16862459-0	2006	N-Glycosylation is required for secretion-competent human plasma phospholipid transfer protein.	Nitrogen	0-1	phospholipid transfer protein	Homo sapiens	65-94
16862459-1	2006	Human plasma phospholipid transfer protein (PLTP) contains six potential N-glycosylation sites (Asn-X-Ser).	Nitrogen	73-74	phospholipid transfer protein	Homo sapiens	13-42
16862459-1	2006	Human plasma phospholipid transfer protein (PLTP) contains six potential N-glycosylation sites (Asn-X-Ser).	Nitrogen	73-74	phospholipid transfer protein	Homo sapiens	44-48
15996511-4	2006	In the light of these results, it was suggested that two ligands coordinate to each metal atom by hydroxyl oxygen, imino nitrogen and thiazole ring nitrogen to form high spin octahedral complexes with Cr(III), Co(II), Ni(II) and Cu(II).	Nitrogen	121-129	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	210-216
16475009-4	2006	The data suggest that N-linked sugar chain patterns of recombinant glycoproteins, produced by the mammary gland differ, since GnT-III alters the sugar pattern extensively.	Nitrogen	22-23	mannoside acetylglucosaminyltransferase 3	Mus musculus	126-133
16202614-5	2006	In fact, the ALR2 inhibition results of compounds 5-7, compared to those of the previously assayed corresponding 5-arylidene-2,4-thiazolidinediones, indicated that N-unsubstituted derivatives 5b, c and d, which bore an additional aromatic group in the para position of the 5-benzyl residue, were significantly more effective than their 5-arylidene counterparts; in all other cases, the saturation of the exocyclic double bond CC in 5 brought about a moderate decrease in activity.	Nitrogen	164-165	aldo-keto reductase family 1 member B	Homo sapiens	13-17
16417271-0	2006	PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions.	Nitrogen	4-12	erb-b2 receptor tyrosine kinase 2	Homo sapiens	61-70
16409042-0	2006	Electron spin relaxation of N@C60 in CS2 in CS2.	Nitrogen	28-29	chorionic somatomammotropin hormone 2	Homo sapiens	37-40
16409042-0	2006	Electron spin relaxation of N@C60 in CS2 in CS2.	Nitrogen	28-29	chorionic somatomammotropin hormone 2	Homo sapiens	44-47
16417271-3	2006	To improve the efficiency of binding between PNAs and the HER-2/neu promoter, mono- and bis-pyrimidine-rich PNAs were conjugated to a nitrogen mustard at either the amino or carboxy terminus.	Nitrogen	134-142	erb-b2 receptor tyrosine kinase 2	Homo sapiens	58-67
16417271-7	2006	Transient transfection experiments demonstrated that the PNA-nitrogen mustard conjugates suppressed HER-2/neu expression by up to 80%.	Nitrogen	61-69	erb-b2 receptor tyrosine kinase 2	Homo sapiens	100-109
16213146-5	2006	To compare the binding mode of N-trifluoroacetyl derivative with that of the lead molecule, we also determined the structure of GPb-NAG complex at a higher resolution (1.9 angstroms).	Nitrogen	31-32	N-acetyl-alpha-glucosaminidase	Homo sapiens	132-135
16467879-12	2006	These results supported the mechanism that blocking of GnT-V expression impaired functions of chaperones and N-glycan-synthesizing enzymes, which caused UPR in vivo.	Nitrogen	109-110	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	55-60
16377736-0	2006	The two senescence-related markers, GS1 (cytosolic glutamine synthetase) and GDH (glutamate dehydrogenase), involved in nitrogen mobilization, are differentially regulated during pathogen attack and by stress hormones and reactive oxygen species in Nicotiana tabacum L. leaves.	Nitrogen	120-128	glutamine synthetase	Nicotiana tabacum	51-71
16399498-2	2006	In a recent issue of Cell, show that altering N-glycosylation of the GLUT2 glucose transporter prevents its anchoring and retention at the cell surface; this impairs glucose uptake and insulin secretion.	Nitrogen	46-47	insulin	Homo sapiens	185-192
16411654-6	2006	The substrate specificity of AOX was characterized as follows: Neonicotinoids with a tertiary nitrogen (N-methylimidacloprid and thiamethoxam) are poor substrates; nitroguanidines are metabolized faster than nitromethylenes; and clothianidin is the most rapidly reduced.	Nitrogen	94-102	aldehyde oxidase 1	Homo sapiens	29-32
16802848-10	2006	Clearance is hepatic via N-oxidation by the hepatic cytochrome P450 (CYP) isoenzymes, CYP2C19, CYP2C9 and CYP3A4.	Nitrogen	25-26	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	52-67
16802848-10	2006	Clearance is hepatic via N-oxidation by the hepatic cytochrome P450 (CYP) isoenzymes, CYP2C19, CYP2C9 and CYP3A4.	Nitrogen	25-26	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	69-72
16802848-10	2006	Clearance is hepatic via N-oxidation by the hepatic cytochrome P450 (CYP) isoenzymes, CYP2C19, CYP2C9 and CYP3A4.	Nitrogen	25-26	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	106-112
16323247-7	2006	The cleaved N-terminal but not C-terminal fragment of TRAF1 was responsible for inhibiting TRIF signaling.	Nitrogen	12-13	TIR domain containing adaptor molecule 1	Homo sapiens	91-95
20141508-5	2006	This is achieved either by directly coordinating to the metal ion found in some metalloenzymes (CAs, CPA, STS), usually by means of one of the nitrogen atoms present in the sulfamide motif, or, as in the case of the cyclic sulfamides, acting as HIV protease inhibitors interacting with the catalytically critical aspartic acid residues of the active site by means of an oxygen atom belonging to the HN-SO(2)-NH motif that substitutes a catalytically essential water molecule.	Nitrogen	143-151	carboxypeptidase A1	Homo sapiens	101-104
16366609-6	2005	The introduction of a tetrahydropyrido ring with bulky hydrophobic substituents at the basic nitrogen provided inhibitors of AChE which were completely inactive toward CEase.	Nitrogen	93-101	acetylcholinesterase (Cartwright blood group)	Homo sapiens	125-129
16365103-1	2006	During renal failure, abnormalities of BCAA and branched-chain keto acid (BCKA) metabolism are due to both the lack of renal contribution to amino acid metabolism and the impact of renal failure and acidosis on whole-body nitrogen metabolism.	Nitrogen	222-230	AT-rich interaction domain 4B	Homo sapiens	39-43
16230337-0	2005	Recombinant addition of N-glycosylation sites to the basolateral Na,K-ATPase beta1 subunit results in its clustering in caveolae and apical sorting in HGT-1 cells.	Nitrogen	24-25	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	77-82
16230337-6	2005	Accordingly, up to five additional N-glycosylation sites homologous to the ones present in the beta2 subunit were successively introduced in the beta1 subunit by site-directed mutagenesis.	Nitrogen	35-36	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	145-150
16251720-7	2006	Flow cytometry, immunoblotting, and immunohistochemistry using anti-moesin antibody showed that the HDL/apoA-I binding protein was N-glycosylated and expressed on the cell surface.	Nitrogen	131-132	moesin	Homo sapiens	68-74
16390417-0	2006	Expression patterns of two glutamine synthetase genes in zygotic and somatic pine embryos support specific roles in nitrogen metabolism during embryogenesis.	Nitrogen	116-124	glutamate-ammonia ligase	Homo sapiens	27-47
16037491-1	2005	Defects in the biosynthesis of N- and core 1 O-glycans may be found by isoelectric focusing (IEF) of plasma transferrin and apolipoprotein C-III (apoC-III).	Nitrogen	31-32	transferrin	Homo sapiens	108-119
16308562-3	2005	In Saccharomyces cerevisiae, the conserved protein kinase A (PKA) and rapamycin-sensitive TOR (TORC1) pathways antagonize G0 entry in response to carbon and/or nitrogen availability primarily by inhibiting the PAS kinase Rim15 function.	Nitrogen	160-168	protein kinase RIM15	Saccharomyces cerevisiae S288C	221-226
16331960-8	2005	It was clear from the transferrin digestions analyzed by HPLC that N-linked glycosylation did confer protection from proteolysis by chymotrypsin.	Nitrogen	67-68	transferrin	Homo sapiens	22-33
16083996-0	2005	Does growth hormone allow more efficient nitrogen sparing in postoperative patients requiring parenteral nutrition?	Nitrogen	41-49	growth hormone 1	Homo sapiens	5-19
16083996-13	2005	CONCLUSION: After major gastrointestinal surgery, GH causes a marked hepatic IGF-I response and nitrogen retention but its effect on body composition was more significant with a high PN input.	Nitrogen	96-104	growth hormone 1	Homo sapiens	50-52
16150905-7	2005	This nuclear FSTL3 was N-glycosylated, although not to the same degree as secreted FSTL3.	Nitrogen	23-24	follistatin like 3	Homo sapiens	13-18
16150913-0	2005	Both saturated and n-6 polyunsaturated fat diets reduce phosphorylation of insulin receptor substrate-1 and protein kinase B in muscle during the initial stages of in vivo insulin stimulation.	Nitrogen	16-17	insulin receptor substrate 1	Rattus norvegicus	75-103
16269134-2	2005	The T309V mutant of CYP2D6 displayed a strong shift from O-dealkylation to N-dealkylation reactions in oxidation of dextromethorphan and 3,4-methylenedioxymethylamphetamine.	Nitrogen	75-76	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	20-26
16316217-1	2005	A new zirconium-mediated, regio- and stereospecific SN2" substitution of allylic ethers with a nitrogen nucleophile has been developed.	Nitrogen	95-103	solute carrier family 38 member 5	Homo sapiens	52-55
16277526-5	2005	In sharp contrast, for secondary diamines L with bulk on chelate ring nitrogens (e.g., 2,2"-bipiperidine, Bip), unexpectedly stable duplexes having two platinated strands (even a unique G3,G4/G4,G5 heteroduplex) were formed.	Nitrogen	70-79	growth differentiation factor 10	Homo sapiens	106-109
16471322-7	2005	WT1 transcripts increased when clinical factors worsen, including the stage, amount of M protein, Hb, platelet count, blood urea nitrogen (BUN), creatinine, serum alkaline phosphatase (ALP), calcium, beta2-microglobulin, thymidine kinase activity (TK), and C-reactive protein (CRP).	Nitrogen	129-137	WT1 transcription factor	Homo sapiens	0-3
16212939-5	2005	In contrast, the mutant containing an additional N-glycosylation site on the N-terminal 24 amino acids of hIL-1beta (Gln15Asn) secreted twice as much rhG-CSF into culture media as wild type hIL-1beta.	Nitrogen	49-50	interleukin 1 beta	Homo sapiens	106-115
15926890-2	2005	In the present study, we examined the importance of N-glycosylation for the ability of C2GnT-I and FucT-VII to generate functional selectin ligands, particularly the PSGL-1 (P-selectin glycoprotein ligand-1).	Nitrogen	52-53	fucosyltransferase 7	Homo sapiens	99-107
16267323-1	2005	Glutamine synthetase plays a major role in ammonia detoxification, interorgan nitrogen flux, acid-base homeostasis, and cell signaling.	Nitrogen	78-86	glutamate-ammonia ligase	Homo sapiens	0-20
16126345-7	2005	Genetic and biochemical characterization of oligosaccharide transferase (OST) complex in yeast and mammalian cells have demonstrated the importance of specific OST subunits in protein N-glycosylation.	Nitrogen	184-185	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	73-76
16126345-7	2005	Genetic and biochemical characterization of oligosaccharide transferase (OST) complex in yeast and mammalian cells have demonstrated the importance of specific OST subunits in protein N-glycosylation.	Nitrogen	184-185	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	160-163
15926890-4	2005	All combined, our results show a differential functional impact of N-glycosylation on C2GnT-1 and FucT-VII and disclose that a strongly reduced FucT-VII activity retains the ability to fucosylate PSGL-1 on the core2-based binding site(s) for the three selectins.	Nitrogen	67-68	fucosyltransferase 7	Homo sapiens	98-106
15926890-4	2005	All combined, our results show a differential functional impact of N-glycosylation on C2GnT-1 and FucT-VII and disclose that a strongly reduced FucT-VII activity retains the ability to fucosylate PSGL-1 on the core2-based binding site(s) for the three selectins.	Nitrogen	67-68	fucosyltransferase 7	Homo sapiens	144-152
16135359-2	2005	Typical CYP2D6 substrates generally contain a basic nitrogen atom and an aromatic moiety adjacent to the site of metabolism.	Nitrogen	52-60	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	8-14
16100110-0	2005	Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation.	Nitrogen	104-105	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase anchoring subunit ALG14	Saccharomyces cerevisiae S288C	0-5
16212391-1	2005	Dependence of conformer formation on a change in bidentate carrier ligand from an sp3 to an sp2 nitrogen donor.	Nitrogen	96-104	Sp3 transcription factor	Homo sapiens	82-85
16212391-1	2005	Dependence of conformer formation on a change in bidentate carrier ligand from an sp3 to an sp2 nitrogen donor.	Nitrogen	96-104	Sp2 transcription factor	Homo sapiens	92-95
16100524-3	2005	The aim of the present study was to determine the effect of alendronate, one of the nitrogen-containing bisphosphonates on the phoshoinositide 3-kinase (PI3K)-Akt-NFkappaB pathway, the major cell survival pathway.	Nitrogen	84-92	AKT serine/threonine kinase 1	Homo sapiens	159-162
16100524-3	2005	The aim of the present study was to determine the effect of alendronate, one of the nitrogen-containing bisphosphonates on the phoshoinositide 3-kinase (PI3K)-Akt-NFkappaB pathway, the major cell survival pathway.	Nitrogen	84-92	nuclear factor kappa B subunit 1	Homo sapiens	163-171
16244137-1	2005	Urease is a nickel-containing urea hydrolase involved in nitrogen recycling from ureide, purine, and arginine catabolism in plants.	Nitrogen	57-65	urease	Arabidopsis thaliana	0-6
16229492-6	2005	Ions at M + n x 31 units were detected in the ESI mass spectra of intact HCalB (n = 1-5) and GAPDH (n = 2), indicating conversion of thiol groups on these proteins to RSONH2 (+31 units).	Nitrogen	2-3	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	93-98
16273650-10	2005	A significant inverse correlation was noted between plasma IL-6 levels and cumulative nitrogen balance postoperatively in the Ala-Gln group, whereas no such correlation was observed in the Conv group.	Nitrogen	86-94	interleukin 6	Homo sapiens	59-63
16273650-12	2005	However, Gln supplementation had a beneficial effect on decreasing systemic IL-6 production after surgery in patients with low admission illness severity, and lower plasma IL-6 may improve nitrogen balance in patients with abdominal surgery when Gln was administered.	Nitrogen	189-197	interleukin 6	Homo sapiens	172-176
16014566-6	2005	These findings indicate that N-linked glycosylation at N92 in human GPVI is not required for surface expression, but contributes to maximal adhesion to type I collagen, CRP and, to a lesser extent, CVX.	Nitrogen	29-30	C-reactive protein	Homo sapiens	169-172
16046125-2	2005	This versatile 8-membered ring containing scaffold possesses an N-5 ring nitrogen that was used to explore structure-activity relationships in a cell-based assay measuring inhibition of interleukin-1beta.	Nitrogen	73-81	interleukin 1 beta	Homo sapiens	186-203
16185063-5	2005	By means of potentiometric and spectroscopic techniques (nuclear magnetic resonance, circular dichroism, UV-vis, and electronic paramagnetic resonance), it was shown that Cu(II) ions coordinate to the chicken PrP hexapeptide domain in physiological pH via imidazole nitrogen donors of His residue(s).	Nitrogen	266-274	prion protein	Homo sapiens	209-212
16100114-3	2005	First, we show that the introduction of an artificial glycosylation site into the N terminus of Pex3p leads to partial N-linked core glycosylation, indicative of insertion into the ER membrane.	Nitrogen	82-83	Pex3p	Saccharomyces cerevisiae S288C	96-101
16131206-5	2005	EPR spectrum of Co(II)-ACMSD provides a high-spin (S = 3/2 mononuclear metal ion in a non-heme, noncorrinoid environment with a mixed nitrogen/oxygen ligand field.	Nitrogen	134-142	aminocarboxymuconate semialdehyde decarboxylase	Homo sapiens	23-28
16160185-0	2005	Identification of two N-linked glycosylation sites within the core of the simian immunodeficiency virus glycoprotein whose removal enhances sensitivity to soluble CD4.	Nitrogen	22-23	CD4 molecule	Homo sapiens	163-166
16156615-2	2005	The electron-donating properties of the pyridyl nitrogen atoms of the resulting complexes (3a,b) were used in complexation reactions with monocationic NCN-pincer (NCN = [C6H3(CH2NMe2)(2-)2,6]-) platinum(II) (11a) and palladium(II) (12a) nitrate complexes [M(NCN)(NO3)], thereby obtaining four trimetallic coordination complexes 16-19.	Nitrogen	48-56	NBL1, DAN family BMP antagonist	Homo sapiens	263-266
16087391-0	2005	Nitrogen-substitution effects on the mutagenicity and cytochrome P450 isoform-selectivity of chrysene analogs.	Nitrogen	0-8	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	54-69
16087391-10	2005	In conclusion, our results suggested that the difference in the nitrogen-substituted position in the chrysene molecule might affect the mutagenic activity through influencing the ratio of participation of the metabolic activation enzyme isoforms of CYP.	Nitrogen	64-72	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	249-252
16103099-2	2005	The predicted amino acid sequence of human RECK includes five putative N-glycosylation sites; however, the precise biochemical role of glycosylated RECK remains unknown.	Nitrogen	71-72	reversion inducing cysteine rich protein with kazal motifs	Homo sapiens	43-47
15931460-5	2005	Glycosidase analysis of cellular and secreted forms confirmed that Fpv060, Fpv061 and Fpv121 were N-glycosylated and that the most abundant, cellular form of Fpv061 had been glycosylated but remained Endo H-sensitive (retained in the endoplasmic reticulum or Golgi).	Nitrogen	98-99	CC chemokine gene family protein	Fowlpox virus	86-92
16392746-0	2005	Regulation of glutamine synthetase and glutamate dehydrogenase in pea mutants rrrbrb, rrRbRb, and RRrbrb during nitrate nitrogen assimilation.	Nitrogen	120-128	glutamate-ammonia ligase	Homo sapiens	14-34
16107153-3	2005	In aldose reductase, Leu300 forms a hydrogen bond through its main-chain nitrogen atom with the exocyclic amide group of the inhibitor, which when replaced with a Pro in aldehyde reductase, cannot form a hydrogen bond, thus causing a loss in binding energy.	Nitrogen	73-81	aldo-keto reductase family 1 member B	Homo sapiens	3-19
15823095-9	2005	Of the five members, only Lass2, Lass5 and Lass6 were N-glycosylated, each at their N-terminal Asn residue.	Nitrogen	54-55	ceramide synthase 5	Homo sapiens	33-38
15956663-1	2005	The [URE3] prion of Saccharomyces cerevisiae is a self-propagating inactive form of the nitrogen catabolism regulator Ure2p.	Nitrogen	88-96	glutathione peroxidase	Saccharomyces cerevisiae S288C	118-123
16123706-5	2005	The aim of this study was to investigate the effects of root canal sealers N2 (zinc-oxide eugenol based) and AH Plus (epoxy resin based) on the expression of IL-6 and IL-8 mRNA gene in human osteoblastic cell line U2OS cells.	Nitrogen	75-77	interleukin 6	Homo sapiens	158-162
16123706-5	2005	The aim of this study was to investigate the effects of root canal sealers N2 (zinc-oxide eugenol based) and AH Plus (epoxy resin based) on the expression of IL-6 and IL-8 mRNA gene in human osteoblastic cell line U2OS cells.	Nitrogen	75-77	C-X-C motif chemokine ligand 8	Homo sapiens	167-171
15890371-5	2005	Blood lymphocytes were also found to catalyze the CYP dependent N-demethylation of N-nitrosodimethylamine (NDMA), which like in liver increased 2-3 fold following pretreatment of rats with known CYP2E1 inducers.	Nitrogen	64-65	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	195-201
16060674-1	2005	To identify the binding site for bovine cytochrome b(5) (cyt b(5)) on horse cytochrome c (cyt c), cross-saturation transfer NMR experiments were performed with (2)H- and (15)N-enriched cyt c and unlabeled cyt b(5).	Nitrogen	124-125	cytochrome b5 type A	Bos taurus	40-55
16060674-1	2005	To identify the binding site for bovine cytochrome b(5) (cyt b(5)) on horse cytochrome c (cyt c), cross-saturation transfer NMR experiments were performed with (2)H- and (15)N-enriched cyt c and unlabeled cyt b(5).	Nitrogen	124-125	cytochrome b5 type A	Bos taurus	57-65
16034098-5	2005	administration of nitrogen-containing bisphosphonate or pyrophosphomonoester drugs into cynomolgus monkeys combined with s.c. low-dose (6 x 10(5) U/animal) IL-2 induces a large pool of CD27+ and CD27- effector/memory T cells in the peripheral blood of treated animals.	Nitrogen	18-26	CD27 antigen	Macaca fascicularis	185-189
16034098-5	2005	administration of nitrogen-containing bisphosphonate or pyrophosphomonoester drugs into cynomolgus monkeys combined with s.c. low-dose (6 x 10(5) U/animal) IL-2 induces a large pool of CD27+ and CD27- effector/memory T cells in the peripheral blood of treated animals.	Nitrogen	18-26	CD27 antigen	Macaca fascicularis	195-199
16833998-1	2005	We have applied cavity ring-down spectroscopy to a kinetic study of the reaction of NO3 with CH3I in 20-200 Torr of N2 diluent at 298 K. The rate constant of the reaction of NO3 + CH3I was determined to be (4.1 +/- 0.2) x 10(-13) cm3 molecule(-1) s(-1) in 100 Torr of N2 diluent at 298 K and is pressure-independent.	Nitrogen	116-118	NBL1, DAN family BMP antagonist	Homo sapiens	84-87
16833998-1	2005	We have applied cavity ring-down spectroscopy to a kinetic study of the reaction of NO3 with CH3I in 20-200 Torr of N2 diluent at 298 K. The rate constant of the reaction of NO3 + CH3I was determined to be (4.1 +/- 0.2) x 10(-13) cm3 molecule(-1) s(-1) in 100 Torr of N2 diluent at 298 K and is pressure-independent.	Nitrogen	116-118	NBL1, DAN family BMP antagonist	Homo sapiens	174-177
16083879-0	2005	Gelatin binding to the 8F19F1 module pair of human fibronectin requires site-specific N-glycosylation.	Nitrogen	86-87	fibronectin 1	Homo sapiens	51-62
16083879-1	2005	The gelatin (denatured collagen) binding domain of the extracellular matrix protein fibronectin contains three potential N-glycosylation sites.	Nitrogen	121-122	fibronectin 1	Homo sapiens	84-95
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	neuropeptide Y	Rattus norvegicus	192-206
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	neuropeptide Y	Rattus norvegicus	208-211
16025565-0	2005	Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR.	Nitrogen	27-28	formyl peptide receptor 1	Homo sapiens	86-89
16025565-0	2005	Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR.	Nitrogen	27-28	formyl peptide receptor 1	Homo sapiens	94-97
16040659-3	2005	Using an Arabidopsis (Arabidopsis thaliana) atg7 mutant unable to ligate either tag, we previously showed that the ATG8/12 conjugation system is important for survival under nitrogen-limiting growth conditions.	Nitrogen	174-182	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	115-119
16262058-1	2005	Correlation and cluster analyses on the enzyme activities and chemical-biological properties of eight red soils showed that soil urease, invertase, phosphatase and catalase activities correlated significantly with soil organic carbon, total nitrogen and total phosphorous.	Nitrogen	241-249	catalase	Homo sapiens	164-172
15982924-9	2005	These changes were less pronounced in SP-A treated membranes; as an example, in the presence of 5.0 microg of SP-A, we observed a total protection of 20:4 n-6 (9.41+/-3.29%) in mitochondria, whereas 7.5 microg of SP-A produced a 65% protection in microsomes (5.95+/-0.73%).	Nitrogen	9-10	surfactant protein A1	Rattus norvegicus	38-42
15784009-0	2005	Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner.	Nitrogen	133-141	interleukin 1 beta	Mus musculus	0-17
15982924-9	2005	These changes were less pronounced in SP-A treated membranes; as an example, in the presence of 5.0 microg of SP-A, we observed a total protection of 20:4 n-6 (9.41+/-3.29%) in mitochondria, whereas 7.5 microg of SP-A produced a 65% protection in microsomes (5.95+/-0.73%).	Nitrogen	9-10	surfactant protein A1	Rattus norvegicus	110-114
15982924-9	2005	These changes were less pronounced in SP-A treated membranes; as an example, in the presence of 5.0 microg of SP-A, we observed a total protection of 20:4 n-6 (9.41+/-3.29%) in mitochondria, whereas 7.5 microg of SP-A produced a 65% protection in microsomes (5.95+/-0.73%).	Nitrogen	9-10	surfactant protein A1	Rattus norvegicus	110-114
16002696-9	2005	Removal of the N-linked glycosylation site from the FcRn H chain resulted in a decreased association of the FcRn H chain for beta(2)m.	Nitrogen	15-16	Fc gamma receptor and transporter	Homo sapiens	52-56
16002696-9	2005	Removal of the N-linked glycosylation site from the FcRn H chain resulted in a decreased association of the FcRn H chain for beta(2)m.	Nitrogen	15-16	Fc gamma receptor and transporter	Homo sapiens	108-112
16050741-1	2005	Quenching mechanisms of the Li3p and Li4p states in collision with the nitrogen molecule are studied by laser-induced fluorescence spectroscopy and by a quantum chemical calculation.	Nitrogen	71-79	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	28-32
15996098-1	2005	Glutamine synthetase is central to nitrogen metabolism in the Gram-negative bacteria.	Nitrogen	35-43	glutamate-ammonia ligase	Homo sapiens	0-20
15926040-6	2005	Finally, we present data supporting that the PHO pathway functions in parallel to the fermentable growth medium- or Sch9-controlled pathway and that both pathways may share the protein kinase Rim15, which was previously reported to play a central role in the integration of glucose, nitrogen and amino acid availability.	Nitrogen	283-291	protein kinase RIM15	Saccharomyces cerevisiae S288C	192-197
15997066-3	2005	Each Co(II) ion is five-coordinated by two O and two N atoms from a Schiff base ligand, and by another bridging phenolate O atom from another Schiff base ligand, giving a severely distorted trigonal-bipyramidal coordination environment.	Nitrogen	53-54	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	5-11
15821045-1	2005	Ifosfamide nephrotoxicity is attributed to the formation of a toxic metabolite, chloroacetaldehyde, via N-dechloroethylation, a reaction that is purportedly catalyzed by CYP3A and CYP2B6.	Nitrogen	104-105	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	170-175
16026326-2	2005	Reactive oxygen and nitrogen species induce DNA single strand breaks, which serve as obligatory triggers for the activation of PARP.	Nitrogen	20-28	poly(ADP-ribose) polymerase 1	Homo sapiens	127-131
15821045-2	2005	Because allelic variants of CYP3A5 are associated with polymorphic expression of microsomal CYP3A5 in human liver and kidneys, we hypothesized that ifosfamide N-dechloroethylation depends on CYP3A5 genotype.	Nitrogen	159-160	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	28-34
15821045-2	2005	Because allelic variants of CYP3A5 are associated with polymorphic expression of microsomal CYP3A5 in human liver and kidneys, we hypothesized that ifosfamide N-dechloroethylation depends on CYP3A5 genotype.	Nitrogen	159-160	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	92-98
15821045-2	2005	Because allelic variants of CYP3A5 are associated with polymorphic expression of microsomal CYP3A5 in human liver and kidneys, we hypothesized that ifosfamide N-dechloroethylation depends on CYP3A5 genotype.	Nitrogen	159-160	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	92-98
15821045-6	2005	In human liver microsomes matched for CYP3A4 protein content, N-dechloroethylation was more than 2-fold higher in that from donors carrying CYP3A5*1 allele that express CYP3A5 relative to that from donors homozygous for the mutant CYP3A5*3.	Nitrogen	62-63	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	38-44
15821045-6	2005	In human liver microsomes matched for CYP3A4 protein content, N-dechloroethylation was more than 2-fold higher in that from donors carrying CYP3A5*1 allele that express CYP3A5 relative to that from donors homozygous for the mutant CYP3A5*3.	Nitrogen	62-63	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	140-146
15821045-6	2005	In human liver microsomes matched for CYP3A4 protein content, N-dechloroethylation was more than 2-fold higher in that from donors carrying CYP3A5*1 allele that express CYP3A5 relative to that from donors homozygous for the mutant CYP3A5*3.	Nitrogen	62-63	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	169-175
15821045-6	2005	In human liver microsomes matched for CYP3A4 protein content, N-dechloroethylation was more than 2-fold higher in that from donors carrying CYP3A5*1 allele that express CYP3A5 relative to that from donors homozygous for the mutant CYP3A5*3.	Nitrogen	62-63	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	169-175
15821045-8	2005	In hepatic microsomes not expressing CYP3A5 protein, ifosfamide N-dechloroethylation was inhibited 53 to 61% and 0 to 3% by monoclonal antibodies specific for CYP3A4/5 or CYP2B6, respectively.	Nitrogen	64-65	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	159-165
15948827-0	2005	Characterization of transgenic poplar with ectopic expression of pine cytosolic glutamine synthetase under conditions of varying nitrogen availability.	Nitrogen	129-137	glutamate-ammonia ligase	Homo sapiens	80-100
15948967-6	2005	Although GDH3 pertains to the nitrogen metabolic network, and its expression is Gln3p-regulated, complete derepression is ultimately determined by the carbon source through the action of the SAGA and SWI/SNF chromatin remodelling complexes.	Nitrogen	30-38	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	9-13
15948967-7	2005	GDH3 carbon-mediated regulation is over-imposed to that exerted by the nitrogen source, highlighting the fact that operation of facultative metabolism requires strict control of enzymes, like Gdh3p, involved in biosynthetic pathways that use tricarboxylic acid cycle intermediates.	Nitrogen	71-79	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	0-4
15948967-7	2005	GDH3 carbon-mediated regulation is over-imposed to that exerted by the nitrogen source, highlighting the fact that operation of facultative metabolism requires strict control of enzymes, like Gdh3p, involved in biosynthetic pathways that use tricarboxylic acid cycle intermediates.	Nitrogen	71-79	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	192-197
15948827-1	2005	The present study addresses the hypothesis that enhanced expression of glutamine synthetase (GS) in transgenic poplar, characterized by the ectopic expression of pine cytosolic GS, results in an enhanced efficiency of nitrogen (N) assimilation and enhanced growth.	Nitrogen	218-226	glutamate-ammonia ligase	Homo sapiens	71-91
15948827-1	2005	The present study addresses the hypothesis that enhanced expression of glutamine synthetase (GS) in transgenic poplar, characterized by the ectopic expression of pine cytosolic GS, results in an enhanced efficiency of nitrogen (N) assimilation and enhanced growth.	Nitrogen	218-226	glutamate-ammonia ligase	Homo sapiens	93-95
15948236-15	2005	CONCLUSION: A stable MDR1 HCC cell line has been established which could recover from liquid nitrogen and CIK from HCC patients has strong cytotoxicity to MDR HCC cell.	Nitrogen	93-101	ATP binding cassette subfamily B member 1	Homo sapiens	21-25
15941833-8	2005	Rapid and transient activation of endothelial NAD(P)H oxidases was responsible for the initial burst production of O2* (Rac1 inhibitor NSC 23766 but not an N-nitro-L-arginine-methyl ester-attenuated ESR O2*- signal at 30 min) in response to angiotensin II, preceding a second peak in O2*- production at 24 h that predominantly depended on uncoupled eNOS.	Nitrogen	46-47	angiotensinogen	Homo sapiens	241-255
15934732-1	2005	The reaction of fac-[NEt(4)](2)[Re(CO)(3)Br(3)] with (S)-(2-(2"-pyridyl)ethyl)cysteamine, L(1), in methanol leads to the formation of the cationic fac-[Re(CO)(3)(NSN)][Br] complex, 1, with coordination of the nitrogen of the pyridine, the sulfur of the thioether, and the nitrogen of the primary amine.	Nitrogen	209-217	FA complementation group C	Homo sapiens	16-19
15934732-1	2005	The reaction of fac-[NEt(4)](2)[Re(CO)(3)Br(3)] with (S)-(2-(2"-pyridyl)ethyl)cysteamine, L(1), in methanol leads to the formation of the cationic fac-[Re(CO)(3)(NSN)][Br] complex, 1, with coordination of the nitrogen of the pyridine, the sulfur of the thioether, and the nitrogen of the primary amine.	Nitrogen	272-280	FA complementation group C	Homo sapiens	16-19
15932337-1	2005	The intramolecular hydroamination of alkynes tethered with amino group 1 in the presence of catalytic amounts of Pd(PPh3)4 and PPh3 in benzene at 100 degrees C proceeded smoothly without the use of any additional acid source to afford five- and six-membered nitrogen heterocycles 2 in good to excellent yields.	Nitrogen	258-266	caveolin 1	Homo sapiens	116-120
15932337-1	2005	The intramolecular hydroamination of alkynes tethered with amino group 1 in the presence of catalytic amounts of Pd(PPh3)4 and PPh3 in benzene at 100 degrees C proceeded smoothly without the use of any additional acid source to afford five- and six-membered nitrogen heterocycles 2 in good to excellent yields.	Nitrogen	258-266	caveolin 1	Homo sapiens	127-131
16228642-2	2005	Results revealed that amino acid hydropathy correlates strongly with the sp2 nitrogen atom numbers in nucleobases rather than with the overall electronic property such as redox potentials of the bases, reflecting that stereo-electronic property of bases may play a role.	Nitrogen	77-85	Sp2 transcription factor	Homo sapiens	73-76
15686448-0	2005	Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.	Nitrogen	138-139	beta-1,2-xylosyltransferase	Arabidopsis thaliana	21-47
15686448-4	2005	Characterization of the N-glycosylation status of recombinant XylT revealed that all three potential N-glycosylation sites of the protein are occupied by N-linked oligosaccharides.	Nitrogen	24-25	beta-1,2-xylosyltransferase	Arabidopsis thaliana	62-66
15686448-4	2005	Characterization of the N-glycosylation status of recombinant XylT revealed that all three potential N-glycosylation sites of the protein are occupied by N-linked oligosaccharides.	Nitrogen	101-102	beta-1,2-xylosyltransferase	Arabidopsis thaliana	62-66
15686448-9	2005	These experiments revealed that the substrate specificity of XylT permits the enzyme to act at multiple stages of the plant N-glycosylation pathway.	Nitrogen	124-125	beta-1,2-xylosyltransferase	Arabidopsis thaliana	61-65
15920059-6	2005	RESULTS: Insulin-mediated glucose disposal was decreased by BR-HF condition (-24 +/- 6%, P &lt; 0.05) but did not change with BR-HCHO (+19 +/- 10%, NS).	Nitrogen	148-150	insulin	Homo sapiens	9-16
15911217-5	2005	Since a decrease in the lectin binding was found in several glycoproteins including fibronectin (FN)-receptor, effect of the changes in N-glycosylation of the cells on cell adhesion to FN-matrix was examined.	Nitrogen	98-99	fibronectin 1	Homo sapiens	84-95
16334266-3	2005	The results indicated that the nitrogen application increased the concentration of NH4-N and NO3-N in the leachate collected under both the soils.	Nitrogen	31-39	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
15930469-5	2005	Transamination provides a mechanism for dispersing BCAA nitrogen according to the tissue"s requirements for glutamate and other dispensable amino acids.	Nitrogen	56-64	AT-rich interaction domain 4B	Homo sapiens	51-55
15930469-6	2005	The intracellular compartmentalization of the branched-chain aminotransferase isozymes (mitochondrial branched-chain aminotransferase, cytosolic branched-chain aminotransferase) impacts on intra- and interorgan exchange of BCAA metabolites, nitrogen cycling, and net nitrogen transfer.	Nitrogen	241-249	AT-rich interaction domain 4B	Homo sapiens	223-227
15930469-6	2005	The intracellular compartmentalization of the branched-chain aminotransferase isozymes (mitochondrial branched-chain aminotransferase, cytosolic branched-chain aminotransferase) impacts on intra- and interorgan exchange of BCAA metabolites, nitrogen cycling, and net nitrogen transfer.	Nitrogen	267-275	AT-rich interaction domain 4B	Homo sapiens	223-227
15930670-2	2005	In both structures, the Co(III) atom is six-coordinated in an octahedral configuration by two N atoms and two O atoms of one Schiff base, and two terminal N or S atoms from two bridging ligands.	Nitrogen	94-95	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	24-31
15933030-4	2005	Transcript level analysis revealed that among the five thiamine-pyrophospate-dependent decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3), only ARO10 was transcriptionally up-regulated when phenylalanine, leucine, or methionine was used as a nitrogen source compared to growth on ammonia, proline, and asparagine.	Nitrogen	242-250	indolepyruvate decarboxylase 1	Saccharomyces cerevisiae S288C	103-107
15933030-4	2005	Transcript level analysis revealed that among the five thiamine-pyrophospate-dependent decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3), only ARO10 was transcriptionally up-regulated when phenylalanine, leucine, or methionine was used as a nitrogen source compared to growth on ammonia, proline, and asparagine.	Nitrogen	242-250	indolepyruvate decarboxylase 5	Saccharomyces cerevisiae S288C	109-113
16019536-3	2005	We now report that a staurosporine derivative, N-benzoylated staurosporine or PKC412, induces cell death in myeloma cell lines (RPMI8226S, U266, MM1S and MM1R) with loss of mitochondrial membrane potential Delta psi m, caspase 3 and PARP cleavage.	Nitrogen	47-48	caspase 3	Homo sapiens	219-228
15794922-0	2005	A hypomorphic allele of the first N-glycosylation gene, ALG7, causes mitochondrial defects in yeast.	Nitrogen	34-35	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	56-60
15885407-5	2005	When the solution was purged with nitrogen gas to remove DO, less than 10% of the As(III) and As(V) was removed.	Nitrogen	34-42	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	94-99
15757902-3	2005	The contribution of the N-capping motif to the stability and dynamics of the region was investigated by replacing the N-cap residue Asp-209 with a glycine in human glutathione S-transferase A1-1 (hGST A1-1) and in a peptide corresponding to its C-terminal region.	Nitrogen	24-25	BCL2 related protein A1	Homo sapiens	190-194
15757902-3	2005	The contribution of the N-capping motif to the stability and dynamics of the region was investigated by replacing the N-cap residue Asp-209 with a glycine in human glutathione S-transferase A1-1 (hGST A1-1) and in a peptide corresponding to its C-terminal region.	Nitrogen	118-119	BCL2 related protein A1	Homo sapiens	190-194
15755757-3	2005	This study tested the hypothesis that recombinant human GH (rhGH) will induce an anabolic response, as assessed by long-term classic nitrogen-balance techniques, in malnourished MHD patients.	Nitrogen	133-141	growth hormone 1	Homo sapiens	56-58
15934785-9	2005	All compounds showed high affinity to hPEPT1, but only the amides L-Gln(N,N-dimethyl)-Sar and L-Gln(N-piperidinyl)-Sar were translocated by hPEPT1.	Nitrogen	72-73	solute carrier family 15 member 1	Homo sapiens	38-44
15934785-9	2005	All compounds showed high affinity to hPEPT1, but only the amides L-Gln(N,N-dimethyl)-Sar and L-Gln(N-piperidinyl)-Sar were translocated by hPEPT1.	Nitrogen	72-73	solute carrier family 15 member 1	Homo sapiens	140-146
15866423-0	2005	N-linked glycosylation facilitates processing and cell surface expression of rat luteinizing hormone receptor.	Nitrogen	0-1	luteinizing hormone/choriogonadotropin receptor	Rattus norvegicus	81-109
15866423-1	2005	The extracellular domain of the luteinizing hormone (LH) receptor has six potential N-linked glycosylation sites.	Nitrogen	84-85	luteinizing hormone/choriogonadotropin receptor	Rattus norvegicus	32-65
15616123-1	2005	Human apolipoprotein B100 (apoB100) has 19 potential N-glycosylation sites, and 16 asparagine residues were reported to be occupied by high-mannose type, hybrid type, and monoantennary and biantennary complex type oligosaccharides.	Nitrogen	53-54	apolipoprotein B	Homo sapiens	6-25
15616123-1	2005	Human apolipoprotein B100 (apoB100) has 19 potential N-glycosylation sites, and 16 asparagine residues were reported to be occupied by high-mannose type, hybrid type, and monoantennary and biantennary complex type oligosaccharides.	Nitrogen	53-54	apolipoprotein B	Homo sapiens	27-34
15616124-0	2005	Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII.	Nitrogen	18-19	coagulation factor VII	Homo sapiens	84-106
15616124-2	2005	In the present study, however, we demonstrate posttranslational N-glycosylation of recombinant human coagulation factor VII (FVII) in CHO-K1 and 293A cells.	Nitrogen	64-65	coagulation factor VII	Homo sapiens	101-123
15899276-6	2005	The N2O:N2 ratios increased rapidly when NO3- increased from 63 to 363 microM; however, results from monthly surveys showed that environmental parameters other than NO3- availability may be important in controlling the variation in N2O production via denitrification.	Nitrogen	4-6	NBL1, DAN family BMP antagonist	Homo sapiens	41-44
15322741-8	2005	The Bio-PTH/I-PTH ratio was significantly lower in HD patients than in normal individuals, due probably to accumulation of N-truncated PTH fragments in the former.	Nitrogen	123-124	parathyroid hormone	Homo sapiens	8-11
15322741-8	2005	The Bio-PTH/I-PTH ratio was significantly lower in HD patients than in normal individuals, due probably to accumulation of N-truncated PTH fragments in the former.	Nitrogen	123-124	parathyroid hormone	Homo sapiens	14-17
15322741-8	2005	The Bio-PTH/I-PTH ratio was significantly lower in HD patients than in normal individuals, due probably to accumulation of N-truncated PTH fragments in the former.	Nitrogen	123-124	parathyroid hormone	Homo sapiens	14-17
15322741-9	2005	The Bio-PTH/I-PTH ratio correlated significantly in a negative manner with serum calcium (Ca) (r=-0.251, P&lt;0.001) and nutritional marker serum urea nitrogen, protein catabolic rate and serum creatinine.	Nitrogen	151-159	parathyroid hormone	Homo sapiens	8-11
15322741-9	2005	The Bio-PTH/I-PTH ratio correlated significantly in a negative manner with serum calcium (Ca) (r=-0.251, P&lt;0.001) and nutritional marker serum urea nitrogen, protein catabolic rate and serum creatinine.	Nitrogen	151-159	parathyroid hormone	Homo sapiens	14-17
15840385-4	2005	N-Methylation of CTr completely ablated the estrogenic activities of CTr.	Nitrogen	0-1	calcitonin receptor	Homo sapiens	17-20
15835887-1	2005	Oligosaccharyltransferase (OST) catalyzes the cotranslational transfer of high-mannose sugars to nascent polypeptides during N-linked glycosylation in the rough endoplasmic reticulum lumen.	Nitrogen	125-126	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	0-25
15835887-1	2005	Oligosaccharyltransferase (OST) catalyzes the cotranslational transfer of high-mannose sugars to nascent polypeptides during N-linked glycosylation in the rough endoplasmic reticulum lumen.	Nitrogen	125-126	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
15840385-4	2005	N-Methylation of CTr completely ablated the estrogenic activities of CTr.	Nitrogen	0-1	calcitonin receptor	Homo sapiens	69-72
15840385-9	2005	Comparisons of the conformational characteristics among CTr and its two analogs indicated that the estrogenic effects of CTr are highly sensitive to apparently minor structural modifications, and further supported the hypothesis for a central role of hydrogen bonding around the nitrogen atom in CTr binding to the ligand binding site of ERalpha.	Nitrogen	279-287	calcitonin receptor	Homo sapiens	56-59
15840385-9	2005	Comparisons of the conformational characteristics among CTr and its two analogs indicated that the estrogenic effects of CTr are highly sensitive to apparently minor structural modifications, and further supported the hypothesis for a central role of hydrogen bonding around the nitrogen atom in CTr binding to the ligand binding site of ERalpha.	Nitrogen	279-287	calcitonin receptor	Homo sapiens	121-124
15840385-9	2005	Comparisons of the conformational characteristics among CTr and its two analogs indicated that the estrogenic effects of CTr are highly sensitive to apparently minor structural modifications, and further supported the hypothesis for a central role of hydrogen bonding around the nitrogen atom in CTr binding to the ligand binding site of ERalpha.	Nitrogen	279-287	calcitonin receptor	Homo sapiens	121-124
15761664-1	2005	Purple acid phosphatase (PAP), also known as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase (Acp5) is synthesized as an N-glycosylated monomeric latent precursor, which can be processed by limited proteolysis to a disulfide-linked two-subunit form with increased enzyme activity.	Nitrogen	156-157	acid phosphatase 3	Rattus norvegicus	25-28
15769471-2	2005	The crystal structure of rhodopsin has previously revealed that Glu122 and Trp126 on transmembrane helix H3 form a complex hydrogen bonding network with Tyr206 and His211 on H5, while the indole nitrogen of Trp265 on H6 forms a water-mediated hydrogen bond with Asn302 on H7.	Nitrogen	195-203	rhodopsin	Homo sapiens	25-34
15769471-4	2005	The NMR chemical shifts of 15N-labeled tryptophan are consistent with the indole nitrogens of Trp126 and Trp265 becoming more weakly hydrogen bonded between rhodopsin and metarhodopsin II.	Nitrogen	81-90	rhodopsin	Homo sapiens	157-166
15807535-0	2005	N-Linked glycosylation of the human ABC transporter ABCG2 on asparagine 596 is not essential for expression, transport activity, or trafficking to the plasma membrane.	Nitrogen	0-1	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	52-57
15807535-3	2005	Sequence analysis revealed three potential N-linked glycosylation sites in human ABCG2 at amino acids 418, 557, and 596.	Nitrogen	43-44	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	81-86
15780659-3	2005	The signal transduction, triggered in response to nitrogen nutrition that is sensed by the Tor proteins, operates via a regulatory pathway involving the cytoplasmic factor Ure2p.	Nitrogen	50-58	glutathione peroxidase	Saccharomyces cerevisiae S288C	172-177
15871271-3	2005	Conversion of the nitrogens of these triazoles to NH4+ and/ or NO3- ions occurs competitively and depends on the number of amine functions on the five-membered triazole rings.	Nitrogen	18-27	NBL1, DAN family BMP antagonist	Homo sapiens	63-66
15780659-4	2005	When carbon and nitrogen are abundant, the phosphorylated Ure2p anchors the also phosphorylated Gln3p and Nil1p in the cytoplasm.	Nitrogen	16-24	glutathione peroxidase	Saccharomyces cerevisiae S288C	58-63
15723445-6	2005	Administration of an adenovirus encoding CT-1 to NS-398-treated rats restituted normal levels of COX-1, prostaglandins, and VEGF in the liver after partial hepatectomy and restored normal liver regeneration.	Nitrogen	49-51	cytochrome c oxidase I, mitochondrial	Rattus norvegicus	97-102
15657055-5	2005	Single scattering fits of EXAFS data indicate that the metal ions in both native Zn(II)-containing and Co(II)-substituted VanX have the same coordination number and that the metal ions are coordinated by 5 nitrogen/oxygen ligands at approximately 2.0 angstroms.	Nitrogen	206-214	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	103-109
15726141-0	2005	Probing the nature of the Co(III) ion in cobalamins: a comparison of the reaction of aquacobalamin (vitamin B12a) and aqua-10-chlorocobalamin with some anionic and N-donor ligands.	Nitrogen	164-165	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	26-33
15724074-3	2005	For a typical protein molecule (lysozyme) with anisotropic polarizability, it is found that up to 1 kW of continuous-wave near-infrared laser power (depending on dielectric constant), together with cooling to liquid-nitrogen temperatures, may be needed to produce sufficiently accurate alignment for direct observation of the secondary structure of proteins in the reconstructed potential or charge-density map.	Nitrogen	216-224	lysozyme	Homo sapiens	32-40
15783196-5	2005	The macrocyclic nitrogen subsequently attacks the methylene chloride with a classic SN2 trajectory, and although the carbon-chlorine bond breaks, the chloride leaving group does not separate from the newly formed cationic macrocycle, such that the product is a tightly associated ion-pair.	Nitrogen	16-24	solute carrier family 38 member 5	Homo sapiens	84-87
15753287-6	2005	Here we report that direct ER-plasma membrane fusion during phagocytosis requires the ER resident soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein ERS24/Sec22b and that J774-macrophages react toward the challenge of large (3.0-microm) but not small (0.8-microm) particles by triggering this fusion mechanism, allowing them to access the most abundant endogenous membrane source in the cell, the ER.	Nitrogen	106-107	SEC22 homolog B, vesicle trafficking protein	Homo sapiens	184-189
15753287-6	2005	Here we report that direct ER-plasma membrane fusion during phagocytosis requires the ER resident soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein ERS24/Sec22b and that J774-macrophages react toward the challenge of large (3.0-microm) but not small (0.8-microm) particles by triggering this fusion mechanism, allowing them to access the most abundant endogenous membrane source in the cell, the ER.	Nitrogen	106-107	SEC22 homolog B, vesicle trafficking protein	Homo sapiens	190-196
15743517-2	2005	In soybeans (a dicotyledonous legume), the vspA and B genes encode subunits of a dimeric vegetative storage protein that plays an important role in nitrogen storage in vegetative tissues.	Nitrogen	148-156	stem 28 kDa glycoprotein	Glycine max	43-47
15576633-0	2005	The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4.	Nitrogen	12-13	solute carrier family 22 member 11	Homo sapiens	132-137
15731028-0	2005	Susceptibility of germfree phagocyte oxidase- and nitric oxide synthase 2-deficient mice, defective in the production of reactive metabolites of both oxygen and nitrogen, to mucosal and systemic candidiasis of endogenous origin.	Nitrogen	161-169	nitric oxide synthase 2, inducible	Mus musculus	50-73
15735959-4	2005	In aqueous solution or triethylammonium acetate (TEAA) buffer (pH 7.6), (15)N-labelled 1 reacted with cytochrome c to give two monoruthenated protein adducts.	Nitrogen	76-77	cytochrome c, somatic	Homo sapiens	102-114
15743824-5	2005	Progression from G1 into S phase following release from nitrogen starvation also required pfs2+ function.	Nitrogen	56-64	cleavage polyadenylation factor subunit PFS2	Saccharomyces cerevisiae S288C	90-94
15823854-7	2005	Nitrogen isotope data confirm that the rise in NO3 concentrations is directly attributable to effluent N.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	47-50
15823854-7	2005	Nitrogen isotope data confirm that the rise in NO3 concentrations is directly attributable to effluent N.	Nitrogen	0-1	NBL1, DAN family BMP antagonist	Homo sapiens	47-50
15686893-7	2005	From the analysis it appears that the nitrogen atom of the aminoethoxyphenyl substituent and 6-hydroxy substituent of the tetrahydroisoquinoline nucleus play important roles for ER(alpha)/ER(beta) selectivity in addition to R(1) and R(2) substituents.	Nitrogen	38-46	estrogen receptor 1	Homo sapiens	178-187
15652647-0	2005	Radioprotection by N-palmitoylated nonapeptide of human interleukin-1beta.	Nitrogen	19-20	interleukin 1 beta	Homo sapiens	56-73
15590670-7	2005	N-linked glycosylation of AG1 and VG1 was demonstrated to be unnecessary for either HA binding or the formation of ternary complexes.	Nitrogen	0-1	thioredoxin domain containing 12	Homo sapiens	26-29
15675840-3	2005	For example, 2-amino-1-butanol, 6a, was treated with 1 to get the N,O-diPoc compound 7a in 90% yield, which when treated with 1.1 equiv of 2 at room temperature removes the Poc group attached to oxygen while leaving the one attached to nitrogen intact to yield compound 8a in 85% yield.	Nitrogen	236-244	proopiomelanocortin	Homo sapiens	72-75
15694965-6	2005	Glycoprotein analysis revealed that all hSA-16 and hSA-18 isoforms were N-glycosylated, and those of hSA-14 were non-glycosylated.	Nitrogen	72-73	albumin	Homo sapiens	40-43
15642719-13	2005	These new findings highlight the physiological importance of different GS1 isoenzymes in plant nitrogen metabolism.	Nitrogen	95-103	glutamine synthetase	Solanum tuberosum	71-74
15785851-1	2005	Genetic studies in Lotus japonicus and pea have identified Nin as a core symbiotic gene required for establishing symbiosis between legumes and nitrogen fixing bacteria collectively called Rhizobium.	Nitrogen	144-152	nin	Lotus japonicus	59-62
15694965-6	2005	Glycoprotein analysis revealed that all hSA-16 and hSA-18 isoforms were N-glycosylated, and those of hSA-14 were non-glycosylated.	Nitrogen	72-73	albumin	Homo sapiens	51-54
15694965-6	2005	Glycoprotein analysis revealed that all hSA-16 and hSA-18 isoforms were N-glycosylated, and those of hSA-14 were non-glycosylated.	Nitrogen	72-73	albumin	Homo sapiens	51-54
15607525-4	2005	The sea bass SHBG (39,894 Da) comprises a tandem repeat of laminin G-like domains typical of SHBG sequences; contains three N-glycosylation sites, and exists as a 118,300 +/- 11,500 Da homodimer.	Nitrogen	124-125	sex hormone-binding globulin	Danio rerio	13-17
15690319-9	2005	In addition, there was an improvement in insulin sensitivity (37.4% +/- 15.2% to 50.4% +/- 23.2%, P &lt; .05) with unchanged sTNFR1 (2.0 +/- 0.8 to 2.3 +/- 1.2 microg/L, P = NS) and sTNFR2 (4.8 +/- 1.7 to 4.4 +/- 1.2 microg/L, P = NS) levels.	Nitrogen	174-176	insulin	Homo sapiens	41-48
15585365-6	2005	The results show that CYP3A4 contributes to the oxidation of KR-60436 to pyrrole-KR-60436, O-demethylpyrrole-KR-60436 and N-dehydroxyethyl-KR-60436, and CYP2C9 and CYP2D6 play roles in demethylation of KR-60436 to form the active metabolite, O-demethyl-KR-60436.	Nitrogen	122-123	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	164-170
15692183-4	2005	The expression of SEN1 gene in leaves was enhanced under nutrition stress (nitrogen, phosphate, and potassium starvation), but the expression of SEN1 gene in roots was induced only by phosphate starvation.	Nitrogen	75-83	splicing endonuclease 1	Arabidopsis thaliana	18-22
15585365-6	2005	The results show that CYP3A4 contributes to the oxidation of KR-60436 to pyrrole-KR-60436, O-demethylpyrrole-KR-60436 and N-dehydroxyethyl-KR-60436, and CYP2C9 and CYP2D6 play roles in demethylation of KR-60436 to form the active metabolite, O-demethyl-KR-60436.	Nitrogen	122-123	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	22-28
16440584-3	2005	We have previously shown that minodronate, a nitrogen-containing bisphosphonate, blocked the angiogenic signaling of vascular endothelial growth factor in ECs through its antioxidative properties.	Nitrogen	45-53	vascular endothelial growth factor A	Homo sapiens	117-151
15715171-6	2005	Recombinant PLAP expressed in 293T cells was also found to bind to hemolysin and the binding was found not to be dependent on the N-linked glycosylation of PLAP.	Nitrogen	130-131	alkaline phosphatase, placental	Homo sapiens	12-16
15966752-6	2005	It is extensively metabolised by N-dealkylation to norbuprenorphine primarily through cytochrome P450 (CYP) 3A4.	Nitrogen	33-34	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	86-111
15966756-3	2005	Hepatic and intestinal microsomal N-demethylation in vitro is catalysed mainly by cytochrome P450 (CYP) 3A4; however, the role of CYP3A in LAAM disposition in humans in vivo is unknown.	Nitrogen	34-35	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	130-135
15966756-17	2005	CONCLUSION: CYP3A mediates human LAAM N-demethylation and bioactivation to norLAAM and dinorLAAM in vivo.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	12-17
16393888-6	2005	Both CPA and IFO are prodrugs that require activation by hepatic cytochrome P450 (CYP)-catalyzed 4-hydroxylation, yielding cytotoxic nitrogen mustards capable of reacting with DNA molecules to form crosslinks and lead to cell apoptosis and/or necrosis.	Nitrogen	133-141	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	65-80
16393888-6	2005	Both CPA and IFO are prodrugs that require activation by hepatic cytochrome P450 (CYP)-catalyzed 4-hydroxylation, yielding cytotoxic nitrogen mustards capable of reacting with DNA molecules to form crosslinks and lead to cell apoptosis and/or necrosis.	Nitrogen	133-141	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	82-85
16393888-11	2005	The alternative CYP-catalyzed inactivation pathway by N-dechloroethylation generates the neurotoxic and nephrotoxic byproduct chloroacetaldehyde (CAA).	Nitrogen	54-55	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	16-19
15757719-5	2005	In the dry season nitrogen enters the Annan and Daintree estuaries predominantly in the form of PON and DON in roughly equal proportions.	Nitrogen	18-26	paraoxonase 1	Homo sapiens	96-99
16645317-2	2005	Here we review some recent structural studies on three multi-site metal enzymes involved in respiratory processes which represent important branches within the global cycles of nitrogen and sulfur: (i) the multi-heme enzyme cytochrome c nitrite reductase, (ii) the FAD, FeS-enzyme adenosine-5"-phosphosulfate reductase, and (iii) the siroheme, FeS-enzyme sulfite reductase.	Nitrogen	177-185	cytochrome c, somatic	Homo sapiens	224-236
15757719-7	2005	In the wet season the majority of nitrogen enters the estuaries as DON and leaves as PON.	Nitrogen	34-42	paraoxonase 1	Homo sapiens	85-88
15515062-8	2005	Expression experiments using COS-7 cells showed that TESSP-1 was synthesized as a glycoprotein with N-glycosylated carbohydrates.	Nitrogen	100-101	protease, serine 41	Mus musculus	53-60
15665582-3	2004	UV-damage and the damage caused by certain chemotherapeutics including cisplatin and nitrogen mustards are known to be repaired by the nucleotide excision repair (NER) pathway which is reportedly regulated by p53 and its downstream genes.	Nitrogen	85-93	tumor protein p53	Homo sapiens	209-212
16248003-2	2005	Further studies into highly modified sugar derivatives led to the preparation of N-and O-alkylated C10 furanopyrimidine analogues, and this work is described herein.	Nitrogen	81-82	homeobox C10	Homo sapiens	99-102
15569246-3	2005	HpAtg8 is a protein with high sequence similarity to both Pichia pastoris and Saccharomyces cerevisiae Atg8 and appeared to be essential for selective peroxisome degradation (macropexophagy) and nitrogen-limitation induced microautophagy.	Nitrogen	195-203	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	2-6
15610023-3	2004	Insulin residues Phe(B25) and Tyr(B26) have been swapped with the IGF-I-like Tyr(24) and Phe(25) sequence with a simultaneous methylation of the peptide nitrogen of residue Phe(B26).	Nitrogen	153-161	insulin	Homo sapiens	0-7
15527839-3	2004	Our analyses also showed clear shifts in N-linked glycosylation patterns in patients with higher CD4+ T cells, suggesting possible distinct immunological pressures pre- and post-HAART.	Nitrogen	41-42	CD4 molecule	Homo sapiens	97-100
15606119-0	2004	Catalytic enantioselective alkynylation of prochiral sp3 C-H bonds adjacent to a nitrogen atom.	Nitrogen	81-89	Sp3 transcription factor	Homo sapiens	53-56
15595853-3	2004	In contrast, the (1)H and (15)N chemical shifts of N-1H in the PNP.Hx complex are shifted downfield by 3.5 and 7.5 ppm to 15.9 and 178.8 ppm, respectively, upon binding.	Nitrogen	30-31	purine nucleoside phosphorylase	Homo sapiens	63-66
15606203-7	2004	The octahedral geometry around each Pb(II) is satisfied by coordination to 3 nitrogen atoms, two oxygen atoms of the chelating acetate group, and bridging of one of the oxygen atoms of the nearby acetate.	Nitrogen	77-85	submaxillary gland androgen regulated protein 3B	Homo sapiens	36-42
15606213-5	2004	Alternatively, when a tertiary amine nitrogen (X = NR; R = CH(3), CH(2)CH(2)OCH(3)) was introduced in the bridging chain, fac,cis-M(N)Cl(2)(PN(R)P) complexes (M = Tc, 2, 3; M = Re, 8f) were obtained.	Nitrogen	37-45	FA complementation group C	Homo sapiens	122-125
15452127-4	2004	Following analyses of N- and O-linked glycoconjugates of srf-3 and wild type nematodes using a combination of enzymatic degradation, permethylation, and mass spectrometry, we found in srf-3 a 65% reduction of acidic O-linked glycoconjugates containing glucuronic acid and galactose as well as a reduction of N-linked glycoconjugates containing galactose and fucose.	Nitrogen	22-23	UDP-galactose/UDP-N-acetylglucosamine transporter srf-3	Caenorhabditis elegans	57-62
15452127-4	2004	Following analyses of N- and O-linked glycoconjugates of srf-3 and wild type nematodes using a combination of enzymatic degradation, permethylation, and mass spectrometry, we found in srf-3 a 65% reduction of acidic O-linked glycoconjugates containing glucuronic acid and galactose as well as a reduction of N-linked glycoconjugates containing galactose and fucose.	Nitrogen	308-309	UDP-galactose/UDP-N-acetylglucosamine transporter srf-3	Caenorhabditis elegans	184-189
15585841-0	2004	N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells.	Nitrogen	0-1	negative elongation factor complex member C/D, Th1l	Mus musculus	88-91
15574338-6	2004	Our results underscore the importance of N-acetylation in restricting N-ubiquitylation and show, in particular, that ubiquitylation of endogenous p21 either at internal lysines or on the N terminus is unlikely to control its degradation by the proteasome.	Nitrogen	41-42	cyclin dependent kinase inhibitor 1A	Homo sapiens	146-149
15574338-6	2004	Our results underscore the importance of N-acetylation in restricting N-ubiquitylation and show, in particular, that ubiquitylation of endogenous p21 either at internal lysines or on the N terminus is unlikely to control its degradation by the proteasome.	Nitrogen	70-71	cyclin dependent kinase inhibitor 1A	Homo sapiens	146-149
15795993-5	2004	Structure-activity relationship suggested that the nitrogen substituents at C-3 and/or C-20 of steroidal skeleton and the hydrophobic properties of the pregnane skeleton are the key structural features contributed to the inhibitory potency of these steroidal alkaloids against AChE and BChE.	Nitrogen	51-59	ACE-1	Oryctolagus cuniculus	277-281
15557245-2	2004	In this study, the significance of the N-glycosylation of the GP(2a) and GP(5) proteins of PRRSV strain LV was investigated.	Nitrogen	39-40	glycoprotein V platelet	Homo sapiens	73-78
15590777-3	2004	The only nitrogen source utilizable by all studied isolates is ammonia, which is incorporated into glutamate by glutamine synthetase.	Nitrogen	9-17	glutamate-ammonia ligase	Homo sapiens	112-132
15597734-7	2004	Induction of LjODC and LjADC gene expression during nodule development preceded symbiotic nitrogen fixation.	Nitrogen	90-98	adc	Lotus japonicus	23-28
15655705-4	2004	DPP IV cleavage generates N-terminally truncated metabolites (GLP-1 (9-36) amide / (9-37) and GIP (3-42)), which are the major circulating forms.	Nitrogen	26-27	glucagon	Homo sapiens	62-67
15501692-2	2004	Methadone is mostly metabolised in the liver; the main step consists in the N-demethylation by CYP3A4 to EDDP (2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine), an inactive metabolite.	Nitrogen	76-77	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	95-101
15535969-1	2004	The avian eggshell matrix protein ovocleidin-116 (OC-116) contains two N-glycosylation sites in its sequence.	Nitrogen	71-72	matrix extracellular phosphoglycoprotein	Gallus gallus	34-48
15253895-0	2004	Evidence for stabilization of aquaporin-2 folding mutants by N-linked glycosylation in endoplasmic reticulum.	Nitrogen	61-62	aquaporin 2 S homeolog	Xenopus laevis	30-41
15253895-3	2004	During synthesis, a subset of wild-type (WT) AQP2 is covalently modified by N-linked glycosylation at residue Asn123.	Nitrogen	76-77	aquaporin 2 S homeolog	Xenopus laevis	45-49
15253895-5	2004	In all constructs, approximately 15-20% of newly synthesized AQP2 was covalently modified by N-linked glycosylation.	Nitrogen	93-94	aquaporin 2 S homeolog	Xenopus laevis	61-65
15631649-5	2004	(3) The abnormal increase of coagulation factor VII was positively correlated with levels of blood uria nitrogen and serum creatinine before hemodialysis but not after hemodialysis.	Nitrogen	104-112	coagulation factor VII	Homo sapiens	29-51
15530090-0	2004	Silver(I) complexes of a sterically demanding fluorinated triazapentadienyl ligand [N((C3F7)C(Dipp)N)2]- (Dipp = 2,6-diisopropylphenyl).	Nitrogen	84-85	nudix hydrolase 4	Homo sapiens	106-114
15509542-6	2004	Immunoblotting analysis demonstrated that ADAM12m is expressed as an activated N-glycosylated form of approximately 90 kd in glioblastoma tissues.	Nitrogen	79-80	ADAM metallopeptidase domain 12	Homo sapiens	42-48
15454235-3	2004	A 4-substituted benzyl group on one homopiperazine nitrogen was an important moiety for binding affinity to the CCR2b receptor.	Nitrogen	51-59	C-C motif chemokine receptor 2	Homo sapiens	112-117
15454235-5	2004	Introduction of hydroxy groups to appropriate positions in the 3,3-diphenylpropyl group on the other homopiperazine nitrogen increased CCR2b binding activity.	Nitrogen	116-124	C-C motif chemokine receptor 2	Homo sapiens	135-140
15448639-1	2004	Two different roles for SNM (sensitive to nitrogen mustard) proteins have already been described: the SNM1/PSO2-related proteins are involved in the repair of the interstrand crosslink (ICL) and the ARTEMIS proteins are involved in the V(D)J recombination process.	Nitrogen	42-50	OxaA/YidC-like membrane insertion protein	Arabidopsis thaliana	199-206
15342690-0	2004	Role of N-linked glycosylation in the secretion and activity of endothelial lipase.	Nitrogen	8-9	lipase G, endothelial type	Homo sapiens	64-82
15342690-1	2004	Human endothelial lipase (EL), a member of the triglyceride lipase gene family, has five potential N-linked glycosylation sites, two of which are conserved in both lipoprotein lipase and hepatic lipase.	Nitrogen	99-100	lipase G, endothelial type	Homo sapiens	6-24
15342690-1	2004	Human endothelial lipase (EL), a member of the triglyceride lipase gene family, has five potential N-linked glycosylation sites, two of which are conserved in both lipoprotein lipase and hepatic lipase.	Nitrogen	99-100	lipase G, endothelial type	Homo sapiens	26-28
15308759-1	2004	We tested the hypothesis that bifunctional DNA adducts formed by a nitrogen mustard-based anticancer drug were more efficient than monofunctional adducts at causing elevation of p53, consistent with the difference in cytotoxicity.	Nitrogen	67-75	tumor protein p53	Homo sapiens	178-181
15476381-2	2004	Dinuclear copper(II) complexes with N-substituted sulfonamide ligands as superoxide dismutase (SOD) mimics have been investigated.	Nitrogen	36-37	superoxide dismutase 1	Homo sapiens	73-93
15476381-2	2004	Dinuclear copper(II) complexes with N-substituted sulfonamide ligands as superoxide dismutase (SOD) mimics have been investigated.	Nitrogen	36-37	superoxide dismutase 1	Homo sapiens	95-98
15474009-0	2004	N-glycosylation at Asn(491) in the Asn-Xaa-Cys motif of human transferrin.	Nitrogen	0-1	transferrin	Homo sapiens	62-73
15377640-10	2004	Moreover, CYP3A5 exhibited only a moderately slower rate for the initial N-demethylation than did CYP3A4 (intrinsic clearance=41 versus 99 microl/min/nmol, respectively).	Nitrogen	73-74	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	10-16
15500314-3	2004	Both compounds show coordination of the OCN moiety through nitrogen to uranium and were characterized using IR and (1)H, (13)C, (14)N, and (31)P NMR spectroscopy and X-ray diffraction.	Nitrogen	59-67	bone gamma-carboxyglutamate protein	Homo sapiens	40-43
15491653-4	2004	Presently, we found that photolysis of the rigid molecule CL-20 produced NO2-, NO3-, NH3, HCOOH, N2 and N2O.	Nitrogen	97-99	epithelial membrane protein 1	Homo sapiens	58-63
15801542-1	2004	The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitory potential of DA-8159 on CYP enzymes.	Nitrogen	88-89	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	46-61
15801542-1	2004	The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitory potential of DA-8159 on CYP enzymes.	Nitrogen	88-89	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	63-66
15801542-1	2004	The purpose of this paper was to characterize cytochrome P450 (CYP) enzymes involved in N-dealkylation of a new oral erectogenic, DA-8159 to DA-8164, a major circulating active metabolite, in human liver microsomes and to investigate the inhibitory potential of DA-8159 on CYP enzymes.	Nitrogen	88-89	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	273-276
15491225-1	2004	We have carried out a percolation analysis of the adsorption of ethane and nitrogen in SBA-2, a structured mesoporous silica consisting of a hexagonal close-packed (hcp) array of spherical cavities connected by cylindrical channels.	Nitrogen	75-83	WD repeat and SOCS box containing 2	Homo sapiens	87-92
15316006-6	2004	Consistent with this, mutation of beta1 N-glycosylation sites abolished all effects of beta1 on channel gating.	Nitrogen	40-41	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	34-39
15316006-6	2004	Consistent with this, mutation of beta1 N-glycosylation sites abolished all effects of beta1 on channel gating.	Nitrogen	40-41	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	87-92
15469271-6	2004	Coordination of an sp2 nitrogen atom to the ruthenium complex is important for achieving this silylation reaction.	Nitrogen	23-31	Sp2 transcription factor	Homo sapiens	19-22
15351734-4	2004	Interestingly, gentamicin inhibited the chaperone and oxidative refolding activities of CRT when N-glycosylated substrates such as alpha1-antitrypsin and alpha-mannosidase were used as substrates, but it did not inhibit the chaperone activity of CRT when unglycosylated citrate synthase was used.	Nitrogen	97-98	calreticulin	Bos taurus	88-91
15351734-4	2004	Interestingly, gentamicin inhibited the chaperone and oxidative refolding activities of CRT when N-glycosylated substrates such as alpha1-antitrypsin and alpha-mannosidase were used as substrates, but it did not inhibit the chaperone activity of CRT when unglycosylated citrate synthase was used.	Nitrogen	97-98	serpin family A member 1	Bos taurus	131-149
15365656-9	2004	CONCLUSION: CYP2B6, CYP2C8, CYP2D6, and CYP3A4 catalyze LOP N-demethylation in human liver microsomes, and among them, CYP2C8 and CYP3A4 may play a crucial role in LOP metabolism at the therapeutic concentrations of LOP.	Nitrogen	2-3	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	28-34
15365656-9	2004	CONCLUSION: CYP2B6, CYP2C8, CYP2D6, and CYP3A4 catalyze LOP N-demethylation in human liver microsomes, and among them, CYP2C8 and CYP3A4 may play a crucial role in LOP metabolism at the therapeutic concentrations of LOP.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	40-46
15365656-9	2004	CONCLUSION: CYP2B6, CYP2C8, CYP2D6, and CYP3A4 catalyze LOP N-demethylation in human liver microsomes, and among them, CYP2C8 and CYP3A4 may play a crucial role in LOP metabolism at the therapeutic concentrations of LOP.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	130-136
15361141-9	2004	Thus, the functional characterization of AtLHT2, together with our expression and localization studies, strongly suggest that in Arabidopsis flowers, AtLHT2 has a critical function in import of neutral and acidic amino acids into the tapetum cells for synthesis of compounds important for microspore structure and in transfer of organic nitrogen to the locule for pollen development.	Nitrogen	337-345	lysine histidine transporter 2	Arabidopsis thaliana	150-156
15553218-1	2004	PURPOSE: To study the reactivity of C4-substituted 1,4-dihydropyridines (1,4-DHP), with either secondary or tertiary nitrogen in the dihydropyridine ring, toward SIN-1-derived peroxynitrite in aqueous media at pH 7.4.	Nitrogen	117-125	dihydropyrimidinase	Homo sapiens	77-80
15553218-1	2004	PURPOSE: To study the reactivity of C4-substituted 1,4-dihydropyridines (1,4-DHP), with either secondary or tertiary nitrogen in the dihydropyridine ring, toward SIN-1-derived peroxynitrite in aqueous media at pH 7.4.	Nitrogen	117-125	MAPK associated protein 1	Homo sapiens	162-167
15332916-2	2004	Experimental results clearly suggest that the attachment occurs exclusively through the bonding of the two para-nitrogen atoms with the surface without the involvement of the carbon atoms, as evidenced from the retention of the (sp2) C-H stretching mode in HREELS and a significant down shift of 1.6 eV in the binding energy of N 1s.	Nitrogen	112-120	Sp2 transcription factor	Homo sapiens	229-232
15350929-5	2004	In all the above reactions, the Schiff bases replace one molecule of PPh3 and hydride ion from the starting complexes, which indicate that the Ru-N bonds present in the complexes containing heterocyclic nitrogen bases are stronger than the Ru-P.	Nitrogen	203-211	caveolin 1	Homo sapiens	69-73
15327950-0	2004	The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.	Nitrogen	56-57	interleukin 10 receptor subunit beta	Homo sapiens	4-11
15173186-0	2004	Four N-linked glycosylation sites in human toll-like receptor 2 cooperate to direct efficient biosynthesis and secretion.	Nitrogen	5-6	toll like receptor 2	Homo sapiens	43-63
15319333-0	2004	CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.	Nitrogen	61-62	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	8-14
15319483-11	2004	Two hypotheses are discussed to explain these results: (1) NRT2.1 is upregulated by a NO(3)(-) demand signaling, indirectly triggered by lack of NRT1.1-mediated uptake, which overrides feedback repression by N metabolites, and (2) NRT1.1 plays a more direct signaling role, and its transport activity generates an unknown signal required for NRT2.1 repression by N metabolites.	Nitrogen	59-60	nitrate transporter 2:1	Arabidopsis thaliana	342-346
15319483-11	2004	Two hypotheses are discussed to explain these results: (1) NRT2.1 is upregulated by a NO(3)(-) demand signaling, indirectly triggered by lack of NRT1.1-mediated uptake, which overrides feedback repression by N metabolites, and (2) NRT1.1 plays a more direct signaling role, and its transport activity generates an unknown signal required for NRT2.1 repression by N metabolites.	Nitrogen	86-87	nitrate transporter 2:1	Arabidopsis thaliana	59-63
15313009-1	2004	Human thrombopoietin (hTPO) is a heavily glycosylated protein with 6 and 24 potential N- and O-glycosylation sites, respectively.	Nitrogen	86-87	thrombopoietin	Homo sapiens	6-20
15289885-5	2004	The Cox-2 protein was strongly induced 2 h after exposure to n-LDL or Ox-LDL, the induction was maximal after 4 h and sustained for at least 8 h. The effect was specific for Cox-2, as Cox-1 expression was not modulated either by n-LDL or by Ox-LDL.	Nitrogen	16-17	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-9
15289885-5	2004	The Cox-2 protein was strongly induced 2 h after exposure to n-LDL or Ox-LDL, the induction was maximal after 4 h and sustained for at least 8 h. The effect was specific for Cox-2, as Cox-1 expression was not modulated either by n-LDL or by Ox-LDL.	Nitrogen	16-17	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	174-179
15289885-9	2004	The finding that n-LDL and Ox-LDL induces Cox-2 in human endothelial cells through a p38 MAPK, NF-kappaB, CREB dependent pathway thus modulating PGE2 release, suggests a new mechanism by which these lipoproteins induce endothelial dysfunction, sustaining inflammatory processes in the arterial wall.	Nitrogen	6-7	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	42-47
15289885-9	2004	The finding that n-LDL and Ox-LDL induces Cox-2 in human endothelial cells through a p38 MAPK, NF-kappaB, CREB dependent pathway thus modulating PGE2 release, suggests a new mechanism by which these lipoproteins induce endothelial dysfunction, sustaining inflammatory processes in the arterial wall.	Nitrogen	6-7	mitogen-activated protein kinase 14	Homo sapiens	85-88
15350982-7	2004	Alpha-lactalbumin concentration decreased with increasing duration of lactation and was positively correlated with total nitrogen.	Nitrogen	121-129	lactalbumin alpha	Homo sapiens	0-17
15350982-8	2004	On average, alpha-lactalbumin contributed 16% of the total nitrogen content of human milk and consequently an important part of the amino acid content.	Nitrogen	59-67	lactalbumin alpha	Homo sapiens	12-29
15322230-4	2004	Transfection of multidrug-resistant cells with wild-type ubiquitin or treatment with an N-glycosylation inhibitor increased the ubiquitination of P-glycoprotein and increased P-glycoprotein degradation.	Nitrogen	88-89	ATP binding cassette subfamily B member 1	Homo sapiens	146-160
15322230-4	2004	Transfection of multidrug-resistant cells with wild-type ubiquitin or treatment with an N-glycosylation inhibitor increased the ubiquitination of P-glycoprotein and increased P-glycoprotein degradation.	Nitrogen	88-89	ATP binding cassette subfamily B member 1	Homo sapiens	175-189
15288576-4	2004	Enzymatic N-deglycosylation of Fas receptor increased the content of Fas aggregates (approximately 110/120 kDa: five- to sixfold, and approximately 203 kDa: two- to threefold), suggesting that Fas glycosylation is involved in regulating receptor dimerization.	Nitrogen	10-11	Fas cell surface death receptor	Rattus norvegicus	31-43
15280532-0	2004	Total chemical synthesis of N-myristoylated HIV-1 matrix protein p17: structural and mechanistic implications of p17 myristoylation.	Nitrogen	28-29	family with sequence similarity 72 member B	Homo sapiens	65-68
15280532-0	2004	Total chemical synthesis of N-myristoylated HIV-1 matrix protein p17: structural and mechanistic implications of p17 myristoylation.	Nitrogen	28-29	family with sequence similarity 72 member B	Homo sapiens	113-116
15084511-0	2004	Analysis of the site-specific N-glycosylation of beta1,6 N-acetylglucosaminyltransferase V.	Nitrogen	30-31	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	49-90
15274680-5	2004	Number of days from onset of shock (or symptom development) to PMX-DHP initiation was longer in the N-S group than in the S group.	Nitrogen	100-103	dihydropyrimidinase	Homo sapiens	67-70
15216352-1	2004	In the comparison of formamide and urea photocatalytic degradation, despite their similar structures, the final fate of bound nitrogen under illumination with TiO2 has shown a different behaviour; both the rate and the ratio of NH4+ and NO3- ion evolution seem not to be linked to the initial nitrogen oxidation state, but to the carbon oxidation state.	Nitrogen	126-134	NBL1, DAN family BMP antagonist	Homo sapiens	237-240
15208340-7	2004	Aside from the sulphur-specific regulation, the induction of SULTR1;1 and SULTR1;2 high-affinity sulphate transporters by sulphur limitation was dependent on the supply of carbon and nitrogen.	Nitrogen	183-191	sulfate transporter 1;1	Arabidopsis thaliana	61-69
15334559-6	2004	Interestingly, in addition to repressing the activity of genes required for utilization of poor nitrogen sources when yeast are grown in the presence of a good nitrogen source, Ure2p appears to be involved in stimulating some of these same genes in the absence of a good nitrogen source.	Nitrogen	96-104	glutathione peroxidase	Saccharomyces cerevisiae S288C	177-182
15334559-6	2004	Interestingly, in addition to repressing the activity of genes required for utilization of poor nitrogen sources when yeast are grown in the presence of a good nitrogen source, Ure2p appears to be involved in stimulating some of these same genes in the absence of a good nitrogen source.	Nitrogen	160-168	glutathione peroxidase	Saccharomyces cerevisiae S288C	177-182
15334559-6	2004	Interestingly, in addition to repressing the activity of genes required for utilization of poor nitrogen sources when yeast are grown in the presence of a good nitrogen source, Ure2p appears to be involved in stimulating some of these same genes in the absence of a good nitrogen source.	Nitrogen	160-168	glutathione peroxidase	Saccharomyces cerevisiae S288C	177-182
15123612-7	2004	Both proton ((1)H) and nitrogen ((14)N) ENDOR studies of bSOD1 and hSOD1 in the presence of H(2)O(2) revealed a change in the geometry of His-46 (or His-44) and His-48 (or His-46) coordinated to Cu(II) at the active site of WT hSOD1 and bSOD1, respectively.	Nitrogen	23-31	superoxide dismutase 1	Homo sapiens	67-72
15225646-2	2004	Here, we show that the mouse GFRalpha4 is a functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET, but has an almost undetectable capacity to recruit RET into the 0.1% Triton X-100 insoluble membrane fraction.	Nitrogen	56-57	ret proto-oncogene	Mus musculus	184-187
15225646-2	2004	Here, we show that the mouse GFRalpha4 is a functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET, but has an almost undetectable capacity to recruit RET into the 0.1% Triton X-100 insoluble membrane fraction.	Nitrogen	56-57	ret proto-oncogene	Mus musculus	240-243
15381976-0	2004	Transfer of a plant chitinase gene into a nitrogen-fixing Azospirillum and study of its expression.	Nitrogen	42-50	Chi	Hordeum vulgare	20-29
15084511-1	2004	N-acetylglucosaminyltransferase V (GnT-V) catalyzes the addition of a beta1,6-linked GlcNAc to the alpha1,6 mannose of the trimannosyl core to form tri- and tetraantennary N-glycans and contains six putative N-linked sites.	Nitrogen	0-1	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-40
15210806-6	2004	Additionally, ICAM-1 KO mice mounted an unimpaired IFN-gamma response and IFN-gamma-dependent production of reactive nitrogen intermediates and parasite- specific IgG2a.	Nitrogen	117-125	interferon gamma	Mus musculus	74-83
15218184-5	2004	Its C-terminal fragment (UL37(COOH)) is ER-localized and N-glycosylated.	Nitrogen	57-58	envelope glycoprotein UL37	Human betaherpesvirus 5	25-29
15082218-5	2004	After the spot-injury of the brain by liquid nitrogen, the surface size of the wound shrunk more rapidly in the C57BL/6 wild-type mice than the apoE-knock out C57BL/6 mice.	Nitrogen	45-53	apolipoprotein E	Mus musculus	144-148
16240513-5	2004	In the same variant the increases of the total nitrogen content in the ears were observed which may be an evidence of interferon-like protein synthesis in plant similar to the interferon system functioning in animals.	Nitrogen	47-55	interferon kappa	Homo sapiens	118-141
15209495-4	2004	In the presence of calcium, the dissociation constant K(1) for the E(1)(#) complex of PLA2 with decyl sulfate (CMC = 4500 microM) is 70 microM with a Hill coefficient n(1) = 2.1 +/- 0.2; K(2) for E(2)(#) is 750 microM with n(2) = 8 +/- 1, and K(3) for E(3)(#) is 4000 microM with an n(3) value of about 12.	Nitrogen	1-2	phospholipase A2, major isoenzyme	Sus scrofa	86-90
15499773-7	2004	Leaching of N from soils is high and nearly all as NO3-.	Nitrogen	12-13	NBL1, DAN family BMP antagonist	Homo sapiens	51-54
14992686-1	2004	Although the residues that determine the preference of CYP2D6 (cytochrome P450 2D6) for compounds containing a basic nitrogen are well characterized, the contribution of other active site residues to substrate binding and orientation is less well understood.	Nitrogen	117-125	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	55-61
14992686-1	2004	Although the residues that determine the preference of CYP2D6 (cytochrome P450 2D6) for compounds containing a basic nitrogen are well characterized, the contribution of other active site residues to substrate binding and orientation is less well understood.	Nitrogen	117-125	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	63-82
15499773-8	2004	Transformation of N to NO3- in soils results in acidification rates that are high compared to rates found elsewhere.	Nitrogen	18-19	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
15499773-11	2004	The soil flux density of mineral N, which is the sum of N deposition and N mineralization, and which is dominated by the N mineralization flux, may be a good indicator for leaching of NO3- in soils.	Nitrogen	33-34	NBL1, DAN family BMP antagonist	Homo sapiens	184-187
15453498-0	2004	Effect of sodium laurate on ruminal fermentation and utilization of ruminal ammonia nitrogen for milk protein synthesis in dairy cows.	Nitrogen	84-92	casein beta	Bos taurus	97-109
15107452-7	2004	The complex regulation of nitrate reduction is likely to have evolved not only to optimize nitrogen assimilation, but also to prevent and control the formation of toxic, and possibly regulatory, products of NR activities.	Nitrogen	91-99	nitrate reductase 1	Arabidopsis thaliana	207-209
15153095-5	2004	A variety of potential targets of reactive oxygen species and reactive nitrogen species could contribute to ERK1/2 activation.	Nitrogen	71-79	mitogen-activated protein kinase 3	Homo sapiens	108-114
15153095-6	2004	These include cell surface receptors, G proteins, upstream kinases, protein phosphatases and proteasome components, each of which could be direct or indirect targets of reactive oxygen or nitrogen species, thereby modulating the duration and magnitude of ERK1/2 activation.	Nitrogen	188-196	mitogen-activated protein kinase 3	Homo sapiens	255-261
15189427-9	2004	Plasma alpha-amino nitrogen exhibited non-significant (p &gt; 0.01) negative correlation (r = -0.295) with plasma GH but a negative correlation (p &lt; 0.01; r = -0.641) with GH per 100 kg BW.	Nitrogen	19-27	somatotropin	Bubalus bubalis	114-116
15010453-5	2004	The translocation into the ER and proper folding were confirmed by the N-linked glycosylation of a mutant CLN6 polypeptide.	Nitrogen	71-72	CLN6 transmembrane ER protein	Homo sapiens	106-110
14982965-0	2004	A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose levels and modifies lipoprotein profiles in KK-Ay mice.	Nitrogen	172-174	peroxisome proliferator activated receptor alpha	Mus musculus	18-66
15016471-22	2004	The roles of GTK in (a) brain nitrogen, sulfur, and aromatic amino acid/kynurenine metabolism, (b) brain alpha-keto acid metabolism, (c) bioactivation of certain electrophiles in brain, (d) prodrug targeting, and (e) maintenance of normal blood pressure deserve further study.	Nitrogen	30-38	kynurenine aminotransferase 1	Homo sapiens	13-16
15147199-5	2004	Importantly, &gt;30% of the identified genes (71 genes) were found to be associated with carbon (C) and nitrogen (N) metabolism and transport, thereby suggesting that Bmh1/2p may play a major role in the regulation of C/N-responsive cellular processes.	Nitrogen	104-112	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	167-174
15147199-5	2004	Importantly, &gt;30% of the identified genes (71 genes) were found to be associated with carbon (C) and nitrogen (N) metabolism and transport, thereby suggesting that Bmh1/2p may play a major role in the regulation of C/N-responsive cellular processes.	Nitrogen	114-115	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	167-174
15147199-5	2004	Importantly, &gt;30% of the identified genes (71 genes) were found to be associated with carbon (C) and nitrogen (N) metabolism and transport, thereby suggesting that Bmh1/2p may play a major role in the regulation of C/N-responsive cellular processes.	Nitrogen	220-221	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	167-174
15152084-2	2004	In particular, the presence of a nitrogen atom at position 7 in the indolyl nucleus of AW results in a red shift of the absorption maximum and fluorescence emission by 10 and 46 nm, respectively, compared to W. In the present work, we report the chemical synthesis and the conformational and functional characterization of an analog (denoted as Y3AW) of the N-terminal domain 1-47 of hirudin, a highly potent thrombin inhibitor, in which Tyr 3 has been replaced by AW.	Nitrogen	33-41	coagulation factor II, thrombin	Homo sapiens	409-417
15152093-0	2004	Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity.	Nitrogen	22-23	folate hydrolase 1	Homo sapiens	47-76
15152093-6	2004	In this paper we show that N-glycosylation is vital for proper folding and subsequent secretion of human GCPII.	Nitrogen	27-28	folate hydrolase 1	Homo sapiens	105-110
15152093-7	2004	Analysis of the predicted N-glycosylation sites also provides evidence that these sites are critical for GCPII carboxypeptidase activity.	Nitrogen	26-27	folate hydrolase 1	Homo sapiens	105-110
15152093-8	2004	We confirm that all predicted N-glycosylation sites are occupied by an oligosaccharide moiety and show that glycosylation at sites distant from the putative catalytic domain is critical for the NAAG-hydrolyzing activity of GCPII calling the validity of previously described structural models of GCPII into question.	Nitrogen	30-31	folate hydrolase 1	Homo sapiens	223-228
15152093-8	2004	We confirm that all predicted N-glycosylation sites are occupied by an oligosaccharide moiety and show that glycosylation at sites distant from the putative catalytic domain is critical for the NAAG-hydrolyzing activity of GCPII calling the validity of previously described structural models of GCPII into question.	Nitrogen	30-31	folate hydrolase 1	Homo sapiens	295-300
15132696-7	2004	The equilibrium T(m) of the crystalline residues (extended-chain crystallites) was estimated to be 464.5-464.9 K. The free energy values for the surface composed of very short chains with a free end, which are neighboring the air (or nitrogen during DSC scanning), were calculated to be 55.6-56.4 erg cm(-2) for heat of fusion per unit mass = 135 J g(-1).	Nitrogen	234-242	ETS transcription factor ERG	Homo sapiens	125-128
15135526-0	2004	The nitrogen-fixing symbiotic bacterium Mesorhizobium loti has and expresses the gene encoding pyridoxine 4-oxidase involved in the degradation of vitamin B6.	Nitrogen	4-12	GMC family oxidoreductase	Mesorhizobium japonicum MAFF 303099	95-115
15135526-1	2004	The gene product of mll6785 of a nitrogen-fixing symbiotic bacterium Mesorhizobium loti MAFF303099 was identified as pyridoxine 4-oxidase, the first enzyme in the vitamin B6-degradation pathway.	Nitrogen	33-41	GMC family oxidoreductase	Mesorhizobium japonicum MAFF 303099	117-137
15056479-1	2004	Identification of cytochrome P-450 isoenzymes (CYPs) involved in perazine 5-sulphoxidation and N-demethylation was carried out using human liver microsomes and cDNA-expressed human CYPs (Supersomes).	Nitrogen	95-96	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	18-34
15181931-4	2004	Dimerisation and specific binding of PrPc and PrPSc seems critical in PrPSc biosynthesis and is influenced by N-glycosylation and disulfide bond formation.	Nitrogen	110-111	prion protein	Homo sapiens	37-41
15069543-0	2004	Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma.	Nitrogen	20-21	CD40 ligand	Homo sapiens	64-69
15354951-0	2004	[Oxides of nitrogen (NO* and NO2-) as cofactors of the myeloperoxidase system].	Nitrogen	11-19	myeloperoxidase	Homo sapiens	55-70
15354951-8	2004	Another oxide of nitrogen, nitrite, is a good substrate for myeloperoxidase Compound I but slowly reacts with Compound II.	Nitrogen	17-25	myeloperoxidase	Homo sapiens	60-75
15069543-11	2004	From the present results it is possible that reduction of N-glycosylation of the heavy chain of IgM by SW treatment may reduce anti-IgM-induced growth inhibition, and reduction in anti-IgM-induced growth inhibition due to altered N-glycosylation may enhance CD40-CD40L-mediated cell survival through TRAF2 which interacts with both IgM and CD40 in HBL-2 cells.	Nitrogen	58-59	CD40 ligand	Homo sapiens	263-268
15140051-6	2004	Deglycosylation of purified SAP with N-glycanase, and not with O-glycanase, blocked the SAP-mediated inhibition of the uptake.	Nitrogen	37-38	amyloid P component, serum	Mus musculus	28-31
15140051-6	2004	Deglycosylation of purified SAP with N-glycanase, and not with O-glycanase, blocked the SAP-mediated inhibition of the uptake.	Nitrogen	37-38	amyloid P component, serum	Mus musculus	88-91
15875396-4	2004	The aim of this work is to study the retention mechanisms of Cu(II), Ni(II), and Co(II) on a BHA by means of a proper combination of physical and chemical techniques: sorption isotherms, mathematical modeling of these isotherms, molecular modeling, FTIR, and N2 (77 K) and CO2 (273 K) adsorption.	Nitrogen	259-261	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	81-87
14970238-0	2004	Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae.	Nitrogen	79-87	actin	Saccharomyces cerevisiae S288C	0-5
14970238-10	2004	These data indicate the actin cytoskeleton is required for nuclear localization of Gln3 in response to limiting nitrogen but not rapamycin-treatment.	Nitrogen	112-120	actin	Saccharomyces cerevisiae S288C	24-29
14970238-11	2004	Therefore, the actin cytoskeleton either participates in the response of Gln3 intracellular localization to nitrogen limitation before Tor1/2, or Tor1/2 inhibition only mimics the outcome of nitrogen limitation rather than directly regulating it.	Nitrogen	108-116	actin	Saccharomyces cerevisiae S288C	15-20
14970238-11	2004	Therefore, the actin cytoskeleton either participates in the response of Gln3 intracellular localization to nitrogen limitation before Tor1/2, or Tor1/2 inhibition only mimics the outcome of nitrogen limitation rather than directly regulating it.	Nitrogen	191-199	actin	Saccharomyces cerevisiae S288C	15-20
14970212-0	2004	The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.	Nitrogen	24-25	amyloid beta precursor protein	Homo sapiens	34-59
14766747-3	2004	When overexpressed in Escherichia coli, AtSOX enhanced growth on sarcosine as sole nitrogen source, showing that it has SOX activity in vivo, and the recombinant protein catalyzed the oxidation of sarcosine to glycine, formaldehyde, and H(2) O(2) in vitro.	Nitrogen	83-91	sulfite oxidase	Arabidopsis thaliana	40-45
14766747-3	2004	When overexpressed in Escherichia coli, AtSOX enhanced growth on sarcosine as sole nitrogen source, showing that it has SOX activity in vivo, and the recombinant protein catalyzed the oxidation of sarcosine to glycine, formaldehyde, and H(2) O(2) in vitro.	Nitrogen	83-91	sulfite oxidase	Arabidopsis thaliana	42-45
15123251-0	2004	A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones.	Nitrogen	56-57	acetyltransferase	Saccharomyces cerevisiae S288C	12-29
14757761-8	2004	GLN1;4 was another high affinity-type GS1 expressed in nitrogen-starved plants but was 10-fold less abundant than GLN1;1.	Nitrogen	55-63	Haloacid dehalogenase-like hydrolase (HAD) superfamily protein	Arabidopsis thaliana	38-41
14757761-9	2004	These results suggested that dynamic regulations of high and low affinity GS1 isoenzymes at the levels of mRNA and enzyme activities are dependent on nitrogen availabilities and may contribute to the homeostatic control of glutamine synthesis in Arabidopsis roots.	Nitrogen	150-158	Haloacid dehalogenase-like hydrolase (HAD) superfamily protein	Arabidopsis thaliana	74-77
15116844-1	2004	Increased nitrate (NO3) concentrations in streamwaters draining forested catchments are reportedly an early indicator of nitrogen (N) saturation.	Nitrogen	121-129	NBL1, DAN family BMP antagonist	Homo sapiens	19-22
15096062-0	2004	Fe(III) and Co(III) centers with carboxamido nitrogen and modified sulfur coordination: lessons learned from nitrile hydratase.	Nitrogen	45-53	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	3-6
15096062-0	2004	Fe(III) and Co(III) centers with carboxamido nitrogen and modified sulfur coordination: lessons learned from nitrile hydratase.	Nitrogen	45-53	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	12-19
15096062-1	2004	Nitrile hydratase (NHase) is a non-heme Fe(III) or non-corrinoid Co(III) metalloenzyme with an unprecedented coordination sphere comprising deprotonated carboxamido nitrogens and modified Cys-S (-SO(-) and -SO(2)(-)) sulfurs.	Nitrogen	165-174	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	43-46
15096062-1	2004	Nitrile hydratase (NHase) is a non-heme Fe(III) or non-corrinoid Co(III) metalloenzyme with an unprecedented coordination sphere comprising deprotonated carboxamido nitrogens and modified Cys-S (-SO(-) and -SO(2)(-)) sulfurs.	Nitrogen	165-174	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	65-72
14757769-3	2004	In order to understand the structural rules for N-linked glycosylation, we introduced N-linked consensus sequences by site-directed mutagenesis into the polypeptide chain of the recombinant human erythropoietin molecule.	Nitrogen	48-49	erythropoietin	Homo sapiens	196-210
14757769-3	2004	In order to understand the structural rules for N-linked glycosylation, we introduced N-linked consensus sequences by site-directed mutagenesis into the polypeptide chain of the recombinant human erythropoietin molecule.	Nitrogen	86-87	erythropoietin	Homo sapiens	196-210
15065019-11	2004	Combination treatment with LY294002 and TRAIL increased apoptosis of SK-N-SH cells compared with TRAIL alone; these results were further corroborated by complete inhibition of apoptosis by caspase-3 or pan-caspase inhibitor.	Nitrogen	72-73	TNF superfamily member 10	Homo sapiens	40-45
15125467-8	2004	RESULTS: The GLP-2 infusions resulted in a dose-dependent increase in antral emptying time (35%; ns and 75%; P = 0.049) compared to saline, but GLP-2 was less potent than GLP-1, which increased the antral emptying time by 192% (P &lt; 0.001).	Nitrogen	26-28	glucagon	Homo sapiens	13-18
15044735-4	2004	For example, the four water molecules in the inhibitor-free structures of AST and BT are channeled into similar positions in the S1 site, and the nitrogen atom(s) of the inhibitors are found in two cationic binding sites denoted Position1 and Position2.	Nitrogen	146-154	solute carrier family 17 member 5	Homo sapiens	74-77
15003262-12	2004	The (1)H-(15)N NMR correlation spectrum of (15)N-labeled APG8a showed the characteristic signature of a folded protein; thus, the solutes appear to have no deleterious effect on the sample.	Nitrogen	13-14	Ubiquitin-like superfamily protein	Arabidopsis thaliana	57-62
15003262-12	2004	The (1)H-(15)N NMR correlation spectrum of (15)N-labeled APG8a showed the characteristic signature of a folded protein; thus, the solutes appear to have no deleterious effect on the sample.	Nitrogen	15-16	Ubiquitin-like superfamily protein	Arabidopsis thaliana	57-62
14615373-1	2004	Antibody-targeted chemotherapy with gemtuzumab ozogamicin (CMA-676, a CD33-targeted immunoconjugate of N-acetyl-gamma-calicheamicin dimethyl hydrazide [CalichDMH], a potent DNA-binding cytotoxic antitumor antibiotic) is a clinically validated therapeutic option for patients with acute myeloid leukemia (AML).	Nitrogen	103-104	CD33 molecule	Homo sapiens	70-74
15268978-2	2004	The aim was to identify the individual human cytochrome P450 (CYP) enzymes responsible for the in vitro N-demethylation of hydromorphone and to determine the potential effect of the inhibition of this metabolic pathway on the formation of other hydromorphone metabolites.	Nitrogen	104-105	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	45-60
15268978-2	2004	The aim was to identify the individual human cytochrome P450 (CYP) enzymes responsible for the in vitro N-demethylation of hydromorphone and to determine the potential effect of the inhibition of this metabolic pathway on the formation of other hydromorphone metabolites.	Nitrogen	104-105	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	62-65
15104241-10	2004	Taken together, the above data indicate that CYP 19/aromatase is the enzyme responsible for the N-demethylation of LAAM to norLAAM in term human placentas obtained from healthy pregnant women.	Nitrogen	96-97	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	45-51
14980620-6	2004	However, for an efficient iNOS inhibition substitution at the nitrogen of the 1-carbothioamide group is important.	Nitrogen	62-70	nitric oxide synthase 2	Rattus norvegicus	26-30
15040951-1	2004	We carried out fermentations with several nitrogen sources in different concentrations and studied nitrogen regulation by following the transcriptional profile of the general amino-acid permease (GAP1) and the ammonium permeases (MEP1, MEP2, MEP3).	Nitrogen	99-107	amino acid permease GAP1	Saccharomyces cerevisiae S288C	196-200
14961189-7	2004	Despite the compensatory increase in expression of iNOS and nNOS, nitric oxide bioavailability is reduced because of increased reaction rates with superoxide, yielding as by-products reactive nitrogen/oxygen species that induce protein nitration.	Nitrogen	192-200	nitric oxide synthase 2	Homo sapiens	51-55
15012994-2	2004	The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors.	Nitrogen	183-191	mitogen-activated protein kinase 14	Homo sapiens	4-13
14770236-2	2004	The complexes have been functionalised on the secondary nitrogen atom of the macrocyclic ring with different pendant groups for promoting their ability to interact non-covalently with human serum albumin (HSA).	Nitrogen	56-64	albumin	Homo sapiens	190-203
15012994-2	2004	The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors.	Nitrogen	183-191	mitogen-activated protein kinase 14	Homo sapiens	135-144
15012994-2	2004	The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors.	Nitrogen	183-191	mitogen-activated protein kinase 14	Homo sapiens	4-7
14973250-4	2004	Consistent with its expression on the surface of supporting cells in the inner ear, CTL2 contains 10 predicted membrane-spanning regions with multiple N-glycosylation sites.	Nitrogen	151-152	solute carrier family 44 member 2	Homo sapiens	84-88
14970177-4	2004	Although hIL-6 is also N-glycosylated at N73 and multiply O-glycosylated, neither N-linked nor O-linked glycosylation is necessary for IL-6 receptor alpha-dependent binding to gp130 or signaling through JAK1-STAT1/3.	Nitrogen	23-24	interleukin 6	Homo sapiens	9-14
14970177-4	2004	Although hIL-6 is also N-glycosylated at N73 and multiply O-glycosylated, neither N-linked nor O-linked glycosylation is necessary for IL-6 receptor alpha-dependent binding to gp130 or signaling through JAK1-STAT1/3.	Nitrogen	23-24	interleukin 6	Homo sapiens	10-14
14970177-4	2004	Although hIL-6 is also N-glycosylated at N73 and multiply O-glycosylated, neither N-linked nor O-linked glycosylation is necessary for IL-6 receptor alpha-dependent binding to gp130 or signaling through JAK1-STAT1/3.	Nitrogen	41-42	interleukin 6	Homo sapiens	9-14
14970177-4	2004	Although hIL-6 is also N-glycosylated at N73 and multiply O-glycosylated, neither N-linked nor O-linked glycosylation is necessary for IL-6 receptor alpha-dependent binding to gp130 or signaling through JAK1-STAT1/3.	Nitrogen	41-42	interleukin 6	Homo sapiens	10-14
14970177-6	2004	These findings highlight distinct functional roles of N-linked glycosylation in viral and cellular IL-6.	Nitrogen	54-55	interleukin 6	Homo sapiens	99-103
14658030-0	2004	Identification of N-glycosylation sites of the murine neural cell adhesion molecule NCAM by MALDI-TOF and MALDI-FTICR mass spectrometry.	Nitrogen	18-19	neural cell adhesion molecule 1	Mus musculus	84-88
14608012-3	2004	Using unrestrained, whole-body, flow-through plethysmography we found that, by postnatal day 4, the PACAP-null neonates had significantly reduced ventilation during baseline breathing, and blunted responses to both hypoxia (10% O2-90% N2) and hypercapnia (8% CO2-92% air).	Nitrogen	235-237	adenylate cyclase activating polypeptide 1	Mus musculus	100-105
14729370-7	2004	With regard to the proposal that BaP may be activated by human CYP1A1, our results suggest that the nitrogen-substitution at position-10 of BaP may cause the CYP enzyme-specificity in metabolic activation to change from CYP1A1 to CYP1A2.	Nitrogen	100-108	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	63-66
14623876-2	2004	This unusual N-C bond forming reaction is catalyzed by the thiamin diphosphate (ThP2)-dependent enzyme N2-(2-carboxyethyl)arginine synthase.	Nitrogen	13-14	GLI family zinc finger 2	Homo sapiens	80-84
14658030-4	2004	Here we report the mass spectrometric analysis of the six potential N-glycosylation sites of the neural cell adhesion molecule NCAM from adult mouse brain.	Nitrogen	68-69	neural cell adhesion molecule 1	Mus musculus	127-131
14663547-2	2004	A first set of experiments shows that high flow rates of N(2) as curtain gas can induce unfolding of cytochrome c (cyt c) and myoglobin (Mb), under conditions in which the stability of the native protein structure has already been reduced by acidification.	Nitrogen	57-61	cytochrome c, somatic	Homo sapiens	101-113
14663547-2	2004	A first set of experiments shows that high flow rates of N(2) as curtain gas can induce unfolding of cytochrome c (cyt c) and myoglobin (Mb), under conditions in which the stability of the native protein structure has already been reduced by acidification.	Nitrogen	57-61	cytochrome c, somatic	Homo sapiens	115-120
15032854-3	2004	Levels of beta-galactosidase activity were similar in both bacteroids and nodule sections from plants that were solely N(2)-dependent or grown in the presence of 4 mM KNO(3).	Nitrogen	119-123	beta-galactosidase	Glycine max	10-28
15022728-6	2004	Ketoconazole, a selective inhibitor of CYP3A4, and anti-CYP3A4 monoclonal antibodies potently inhibited both N-hydrolysis and hydroxylation of KR-31543 in human liver microsomes.	Nitrogen	109-110	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	39-45
15022728-6	2004	Ketoconazole, a selective inhibitor of CYP3A4, and anti-CYP3A4 monoclonal antibodies potently inhibited both N-hydrolysis and hydroxylation of KR-31543 in human liver microsomes.	Nitrogen	109-110	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	56-62
14965371-0	2004	p53-independent anti-tumor effects of the nitrogen-containing bisphosphonate zoledronic acid.	Nitrogen	42-50	tumor protein p53	Homo sapiens	0-3
14744940-2	2004	N-dealkylated products nor-VER [2,8-bis-(3,4-dimethoxyphenyl)-2-isopropyl-6-azaoctanitrile] and D617 [2-(3,4-dimethoxyphenyl)-5-methylamino-2-isopropylvaleronitrile] were the major metabolites for all CYP3A isoforms regardless of enantiomer.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	201-206
14715687-5	2004	Examples include the neuronal bHLH-PAS carbon monoxide sensor NPAS2 that is implicated in the mammalian circadian clock, the acetobacterial oxygen sensor AxPDEA1 that directs cellulose production, and the rhizobial oxygen sensor FixL, which governs nitrogen fixation.	Nitrogen	249-257	neuronal PAS domain protein 2	Homo sapiens	62-67
14677050-5	2004	Meanwhile, the most stable N13- structure A-2 is composed of a pentazole ring and a six-membered ring connected by two nitrogen atoms.	Nitrogen	119-127	ATPase H+ transporting V0 subunit a2	Homo sapiens	42-45
14968425-1	2004	We have found that proline and the toxic proline analogue azetidine-2-carboxylate (AzC) are efficiently imported into Saccharomyces cerevisiae cells by four amino acid permeases, including two nitrogen-regulated permeases (PUT4 and GAP1) and two permeases that are regulated by the SPS sensor of extracellular amino acids (AGP1 and GNP1).	Nitrogen	193-201	amino acid permease GAP1	Saccharomyces cerevisiae S288C	232-236
14961165-3	2004	Plasma adiponectin before and after adjustment for body composition or calculated insulin resistance increased in slight anemic women (372.6 +/- 2.6 x 10(4)/mm3) compared with non-anemic subjects (471.1 +/- 1.7) (all p &lt; 0.0001), and were inversely associated with red blood cells (RBC), hemoglobin, hematocrit, white blood cells and platelet values (p &lt; 0.0001-0.02), independent of age, diastolic blood pressure, body mass index, serum triglyceride, insulin resistance or blood urea nitrogen.	Nitrogen	491-499	adiponectin, C1Q and collagen domain containing	Homo sapiens	7-18
14968425-1	2004	We have found that proline and the toxic proline analogue azetidine-2-carboxylate (AzC) are efficiently imported into Saccharomyces cerevisiae cells by four amino acid permeases, including two nitrogen-regulated permeases (PUT4 and GAP1) and two permeases that are regulated by the SPS sensor of extracellular amino acids (AGP1 and GNP1).	Nitrogen	193-201	glutamine permease GNP1	Saccharomyces cerevisiae S288C	332-336
14757367-5	2004	The release of TNF-alpha from SAA-stimulated neutrophils is strongly suppressed by the addition of the antioxidants N-acetyl-L-cysteine, alpha-mercaptoethanol, glutathione, the antiinflammatory dexamethasone and the compounds wortmannin (a PI3K inhibitor), PD98059 (a MEK-1 inhibitor) and SB203580 (a p38 inhibitor).	Nitrogen	16-17	mitogen-activated protein kinase 14	Homo sapiens	301-304
14593096-4	2004	Insertion of N-linked glycosylation sites into each of the hydrophilic loop domains and the N terminus of APH-1 showed that the N-terminal domain as well as loops 2, 4, and 6 could be glycosylated, whereas loops 1, 3, and 5 were not.	Nitrogen	13-14	aph-1 homolog A, gamma-secretase subunit	Homo sapiens	106-111
14697254-6	2004	These results suggest Agp2p and Agp3p function in amino acid transport when nitrogen sources are limiting and/or other permeases are inactive.	Nitrogen	76-84	Agp2p	Saccharomyces cerevisiae S288C	22-27
15027190-1	2004	Lipocalin-type prostaglandin D synthase (L-PGDS), an N-glycosylated dual functional monomeric protein, acts as a PGD2-producing enzyme and also as a lipophilic ligand-binding protein.	Nitrogen	53-54	prostaglandin D2 synthase	Homo sapiens	0-39
15027190-1	2004	Lipocalin-type prostaglandin D synthase (L-PGDS), an N-glycosylated dual functional monomeric protein, acts as a PGD2-producing enzyme and also as a lipophilic ligand-binding protein.	Nitrogen	53-54	prostaglandin D2 synthase	Homo sapiens	41-47
14573609-2	2004	The predicted amino acid sequence of heparanase includes six putative N-glycosylation sites; however, the precise biochemical role of glycosylated heparanase remains unknown.	Nitrogen	70-71	heparanase	Homo sapiens	37-47
15356719-4	2004	The structure of L(5) shows 3 methanol solvent molecules all of which form 2 or 3 hydrogen bonds with triazine nitrogen atoms, amide nitrogen or oxygen atoms, or pyridine nitrogen atoms.	Nitrogen	111-119	ribosomal protein L5	Homo sapiens	17-21
15356719-4	2004	The structure of L(5) shows 3 methanol solvent molecules all of which form 2 or 3 hydrogen bonds with triazine nitrogen atoms, amide nitrogen or oxygen atoms, or pyridine nitrogen atoms.	Nitrogen	133-141	ribosomal protein L5	Homo sapiens	17-21
15356719-4	2004	The structure of L(5) shows 3 methanol solvent molecules all of which form 2 or 3 hydrogen bonds with triazine nitrogen atoms, amide nitrogen or oxygen atoms, or pyridine nitrogen atoms.	Nitrogen	133-141	ribosomal protein L5	Homo sapiens	17-21
15356719-9	2004	The electronic charge distribution in L(4) and L(5) is similar to that found in other terdentate ligands such as terpyridine which have equally poor extraction properties and suggests that the unique properties of L(1) evolve from the presence of two adjacent nitrogen atoms in the triazine rings.	Nitrogen	260-268	ribosomal protein L5	Homo sapiens	47-51
15356719-9	2004	The electronic charge distribution in L(4) and L(5) is similar to that found in other terdentate ligands such as terpyridine which have equally poor extraction properties and suggests that the unique properties of L(1) evolve from the presence of two adjacent nitrogen atoms in the triazine rings.	Nitrogen	260-268	immunoglobulin kappa variable 1-16	Homo sapiens	214-218
14745797-3	2004	The NMR data obtained for (15)N-labeled anti-apoptotic Bcl-xL in lipid bilayers are consistent with membrane association through insertion of the two central hydrophobic alpha-helices that are also required for channel formation and cytoprotective activity.	Nitrogen	4-5	BCL2 like 1	Homo sapiens	55-61
12962983-6	2004	The overall structure of IgE, i.e. four constant domains and the positions of putative disulfide-bridge formations, are conserved, as is an N-glycosylation site in the third constant domain.	Nitrogen	140-141	immunoglobulin heavy constant epsilon	Homo sapiens	25-28
14744631-2	2004	In serum-deprived human fibroblasts, exposure to 100 microM N-fMLP or 10 microM peptide W for 1 min induced both p47phox translocation and NADPH-dependent superoxide generation.	Nitrogen	60-61	formyl peptide receptor 1	Homo sapiens	62-66
14977046-0	2004	N-linked glycosylation of the human bradykinin B2 receptor is required for optimal cell-surface expression and coupling.	Nitrogen	0-1	kininogen 1	Homo sapiens	36-46
14694155-7	2004	Qualitative analysis of HSPG, using gel filtration of HNO(2)-treated fractions, showed that AngII treatment decreased N-sulfation of HS-GAG side chains.	Nitrogen	55-56	angiotensinogen	Homo sapiens	92-97
15495951-8	2004	Complete photo-oxidation of nitrogen to NO3- occurred very slowly via the intermediate formation of NH4+ and NO2-.	Nitrogen	28-36	NBL1, DAN family BMP antagonist	Homo sapiens	40-43
14702404-8	2004	Presumably, this interaction electrochemically couples LpDH as the electron donor to ETFN as the electron acceptor, allowing PDH complex activity (pyruvate oxidation) to drive soluble electron transport via ETFN to N2, which acts as the terminal electron acceptor.	Nitrogen	215-217	pyruvate dehydrogenase phosphatase catalytic subunit 1	Homo sapiens	125-128
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	interferon gamma	Homo sapiens	159-168
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	interleukin 4	Homo sapiens	173-177
15272702-3	2004	The dominant soluble nitrogen form was NO3- -N followed by Kjeldahl-N, NO1- -N and non-ionic ammonia.	Nitrogen	21-29	NBL1, DAN family BMP antagonist	Homo sapiens	39-42
14974709-10	2004	Present results have been rationalized based on the assumption that an orientational restriction is imposed for the encounter complexes in quinone-AlA systems to undergo ET reactions, which arises because of the localized (at amino nitrogen) shapes of the highest-occupied molecular orbitals (HOMO) of AlA in comparison to the pi-like HOMO of the ArA.	Nitrogen	232-240	ATP binding cassette subfamily C member 6	Homo sapiens	347-350
15306153-4	2004	When a mixture of 5% CO/95% N(2) was used, the responses were 70+/-7% of control for thrombin and 79+/-6% of control for ADP.	Nitrogen	28-32	coagulation factor II, thrombin	Homo sapiens	85-93
15137421-3	2004	Generation of nitrogen gas (N2) and ammonium nitrogen (NH4-N) was simultaneously observed in the low load of nitrate (NO3-N) (below 0.68 g NO3-N/L).	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	118-121
15137421-3	2004	Generation of nitrogen gas (N2) and ammonium nitrogen (NH4-N) was simultaneously observed in the low load of nitrate (NO3-N) (below 0.68 g NO3-N/L).	Nitrogen	14-22	NBL1, DAN family BMP antagonist	Homo sapiens	139-142
15137421-3	2004	Generation of nitrogen gas (N2) and ammonium nitrogen (NH4-N) was simultaneously observed in the low load of nitrate (NO3-N) (below 0.68 g NO3-N/L).	Nitrogen	28-30	NBL1, DAN family BMP antagonist	Homo sapiens	118-121
15137421-3	2004	Generation of nitrogen gas (N2) and ammonium nitrogen (NH4-N) was simultaneously observed in the low load of nitrate (NO3-N) (below 0.68 g NO3-N/L).	Nitrogen	28-30	NBL1, DAN family BMP antagonist	Homo sapiens	139-142
14675751-4	2003	Little apoptosis of primary porcine chondrocytes is observed at an effective concentration of N-TIMP-3.	Nitrogen	94-95	TIMP metallopeptidase inhibitor 3	Bos taurus	96-102
14651673-3	2003	In this study, we determined the percentage contribution of the three CYPs (CYP2C9, CYP2E1 and CYP3A4) to TMO N-demethylation.	Nitrogen	110-111	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	84-90
14652237-13	2003	CONCLUSIONS: Endoxifen is an active tamoxifen metabolite that is generated via CYP3A4-mediated N-demethylation and CYP2D6-mediated hydroxylation.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	79-85
14651673-3	2003	In this study, we determined the percentage contribution of the three CYPs (CYP2C9, CYP2E1 and CYP3A4) to TMO N-demethylation.	Nitrogen	110-111	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	95-101
14579093-5	2003	Hypoxic conditions generated with a mixture of 95% N(2) and 5% CO(2) reduced cellular uptake of the two tracers in both parental MCF7/WT cells and MRP1-expressing MCF7/VP cells.	Nitrogen	51-55	ATP binding cassette subfamily C member 1	Homo sapiens	147-151
14565980-3	2003	Because conserved cell cycle regulators, the mitotic cyclin-dependent kinase Clb2/Cdc28, and its inhibitor Swe1 were found to be involved in both nitrogen starvation- and short chain alcohol-induced filamentous differentiation, they were identified as components of the core mechanism for filamentous differentiation.	Nitrogen	146-154	tyrosine protein kinase SWE1	Saccharomyces cerevisiae S288C	107-111
12944413-3	2003	In this study, we investigated the contribution of N-glycosyl modification to the structure and function of SERT in two model systems: wild-type SERT expressed in sialic acid-defective Lec4 Chinese hamster ovary (CHO) cells and a mutant form (after site-directed mutagenesis of Asn-208 and Asn-217 to Gln) of SERT, QQ, expressed in parental CHO cells.	Nitrogen	51-52	solute carrier family 6 member 4	Homo sapiens	108-112
12911333-0	2003	Allowed N-glycosylation sites on the Kv1.2 potassium channel S1-S2 linker: implications for linker secondary structure and the glycosylation effect on channel function.	Nitrogen	8-9	potassium voltage-gated channel subfamily A member 2	Homo sapiens	37-42
12911333-5	2003	In the present study, by a scanning mutagenesis approach, we determined the allowed N-glycosylation sites on the Kv1.2 S1-S2 linker, which has 39 amino acids, by engineering N-glycosylation sites and assaying for glycosylation, using their sensitivity to glycosidases.	Nitrogen	84-85	potassium voltage-gated channel subfamily A member 2	Homo sapiens	113-118
12911333-5	2003	In the present study, by a scanning mutagenesis approach, we determined the allowed N-glycosylation sites on the Kv1.2 S1-S2 linker, which has 39 amino acids, by engineering N-glycosylation sites and assaying for glycosylation, using their sensitivity to glycosidases.	Nitrogen	174-175	potassium voltage-gated channel subfamily A member 2	Homo sapiens	113-118
14624640-3	2003	In this strategy, the strong electrophilic [TcN(PNP)](2+) metal fragment efficiently reacts with bifunctional chelating ligands having a pi-donor atom set, such as N-functionalized O,S-cysteine.	Nitrogen	46-47	purine nucleoside phosphorylase	Homo sapiens	48-51
12928435-8	2003	Tunicamycin, an inhibitor of N-linked glycosylation, blocked surface membrane expression of HCN2.	Nitrogen	29-30	hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2	Homo sapiens	92-96
12907690-8	2003	Our results suggest that 3-OST-5 enzyme sulfates both N-sulfated glucosamine and N-unsubstituted glucosamine residues.	Nitrogen	54-55	heparan sulfate-glucosamine 3-sulfotransferase 5	Homo sapiens	25-32
14608071-1	2003	The current WHO/FAO/UNU recommendations for BCAA requirements in school-aged children are based on nitrogen balance studies that have tended to produce lower estimates of amino acid requirements that those determined using stable isotope methodologies.	Nitrogen	99-107	AT-rich interaction domain 4B	Homo sapiens	44-48
14714472-6	2003	The mechanisms whereby MSO and PPT affect glutamine synthetase activity are discussed in the context of nitrogen metabolism in plants.	Nitrogen	104-112	glutamate-ammonia ligase	Homo sapiens	42-62
14559239-1	2003	It has been considered that three key elements participate in nitrogen catabolite repression (NCR) of Saccharomyces cerevisiae: the GLN3 and GAT1/NIL1-encoded transcriptional activators and their negative regulator Ure2.	Nitrogen	62-70	glutathione peroxidase	Saccharomyces cerevisiae S288C	215-219
14617151-8	2003	Specific truncations of the C-terminus of Gap1 (e.g. last 14 or 26 amino acids) did not reduce transport activity but caused the same phenotype as in strains with constitutively high PKA activity also during growth with ammonium as sole nitrogen source.	Nitrogen	237-245	amino acid permease GAP1	Saccharomyces cerevisiae S288C	42-46
14714472-2	2003	This effect is accounted for by impairments of nitrogen metabolism, resulting from inhibition of its key enzyme in plants, glutamine synthetase (EC 6.3.1.2).	Nitrogen	47-55	glutamate-ammonia ligase	Homo sapiens	123-143
14521956-0	2003	Regulation on the expression and N-glycosylation of integrins by N-acetylglucosaminyltransferase V.	Nitrogen	33-34	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	65-98
14531686-3	2003	Every one of the five (15)N-labeled adjacent residues of the peptide exhibited apparently different kinetic exchange and relaxation behaviors, which were especially evident at different concentrations of prothrombin.	Nitrogen	26-27	coagulation factor II, thrombin	Homo sapiens	204-215
12882646-6	2003	p45 and p105, comprised primarily the D1, D2-D3 domains respectively, and were N-glycosylated.	Nitrogen	79-80	caspase-1	Sus scrofa	0-3
12847110-7	2003	Our results suggest that N inhibits angiogenesis not by disrupting the HGF/c-met interaction but rather by interfering with the endothelial glycosaminoglycans, which are the secondary binding sites of HGF.	Nitrogen	25-26	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	75-80
14520472-7	2003	NS-398-treated HT-29 cells showed increased p50 homodimer binding and an induction of p50/p65 heterodimers, as demonstrated by supershift assay.	Nitrogen	0-2	nuclear factor kappa B subunit 1	Homo sapiens	44-47
14520472-7	2003	NS-398-treated HT-29 cells showed increased p50 homodimer binding and an induction of p50/p65 heterodimers, as demonstrated by supershift assay.	Nitrogen	0-2	nuclear factor kappa B subunit 1	Homo sapiens	86-89
14520472-9	2003	This indicates that NF-kappaB activated by NS-398 is transcriptionally inactive and is an encouraging result for the use of COX-2-selective NSAIDs not only in chemoprevention but also as novel therapies for colon cancer.	Nitrogen	43-45	nuclear factor kappa B subunit 1	Homo sapiens	20-29
14520472-9	2003	This indicates that NF-kappaB activated by NS-398 is transcriptionally inactive and is an encouraging result for the use of COX-2-selective NSAIDs not only in chemoprevention but also as novel therapies for colon cancer.	Nitrogen	43-45	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	124-129
14620622-12	2003	CONCLUSION: Insulin resistance in non-alcoholic fatty liver disease patients also affects amino acid metabolism, especially for amino acids involved in peripheral muscle nitrogen exchange.	Nitrogen	170-178	insulin	Homo sapiens	12-19
14502542-10	2003	Kinetic modeling of the data obtained from both HPLC and NMR measurements indicated that in an acidic solution THU beta-ribofuranosyl --&gt; beta-ribopyranosyl isomerization is a rapid equilibrium reaction, which proceeds through an intermediate observable in 1H-NMR, and is followed by slower N-glycosidic bond hydrolysis.	Nitrogen	57-58	inversion, Chr X, Harwell 1	Mus musculus	257-262
12949938-2	2003	PSMA is a type II membrane glycoprotein with a short cytoplasmic N-terminal region, a transmembrane domain, and a 701 amino acid extracellular portion with 10 potential N-linked glycosylation sites.	Nitrogen	65-66	folate hydrolase 1	Homo sapiens	0-4
14530347-4	2003	All Ly-49s contain N-glycosylation motifs; however, the importance of receptor glycosylation in Ly-49-class I interactions has not been determined.	Nitrogen	19-20	killer cell lectin-like receptor, subfamily A	Mus musculus	4-9
14514319-3	2003	The temperature-dependent electronic and spectral properties of solutions containing the [Co(III)(tpy)(Cat-N-SQ)](+) suggest that this compound undergoes a thermally driven valence tautomeric interconversion to [Co(II)(tpy)(Cat-N-BQ)](+) complex, the metal ion being in high-spin configuration.	Nitrogen	107-108	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	90-95
14620918-5	2003	We show that both pyrophosphate-resembling (p-) and nitrogen-containing (n-) BPs induce activation of p38 mitogen activated protein (MAP) kinase pathway in MDA-MB-231 cells in vitro.	Nitrogen	52-60	mitogen-activated protein kinase 14	Homo sapiens	102-105
12970138-13	2003	The proteasome inhibitor N-acetyl-leucinyl-leucinyl-norleucinal (ALLN 100 microM) reduced IFN-gamma/CD40L mediated cytokine induction, suggesting participation of NFkappaB, which was directly demonstrated by EMSA.	Nitrogen	25-26	interferon gamma	Homo sapiens	90-99
12970138-13	2003	The proteasome inhibitor N-acetyl-leucinyl-leucinyl-norleucinal (ALLN 100 microM) reduced IFN-gamma/CD40L mediated cytokine induction, suggesting participation of NFkappaB, which was directly demonstrated by EMSA.	Nitrogen	25-26	CD40 ligand	Homo sapiens	100-105
12970138-13	2003	The proteasome inhibitor N-acetyl-leucinyl-leucinyl-norleucinal (ALLN 100 microM) reduced IFN-gamma/CD40L mediated cytokine induction, suggesting participation of NFkappaB, which was directly demonstrated by EMSA.	Nitrogen	25-26	nuclear factor kappa B subunit 1	Homo sapiens	163-171
14500784-9	2003	These results suggest that Rsp5 is involved in selective degradation of abnormal proteins and specific proteins for spore growth, in addition to nitrogen-regulated degradation of Gap1.	Nitrogen	145-153	amino acid permease GAP1	Saccharomyces cerevisiae S288C	179-183
12829718-6	2003	N-Glycosylation was responsible because peptide N-glycosidase F treatment of isolated 170-kDa EGFR yielded a single band at 145 kDa.	Nitrogen	0-1	epidermal growth factor receptor	Homo sapiens	94-98
12971747-2	2003	Five nitrogen atoms complete the coordination sphere of the Co(II) ion, showing a distorted trigonal bipyramid geometry.	Nitrogen	5-13	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	60-66
12941430-12	2003	Moreover, N-glycosylation of the N-terminus seems to be important for constitutive FPR activity.	Nitrogen	10-11	formyl peptide receptor 1	Homo sapiens	83-86
12829718-10	2003	These results establish a novel mechanism by which glucose-dependent EGFR N-glycosylation modulates AngII signal transduction and suggest a potential mechanism for pathogenic effects of AngII in diabetic vasculopathy.	Nitrogen	74-75	epidermal growth factor receptor	Homo sapiens	69-73
14507038-0	2003	The association between milk urea nitrogen and DHI production variables in western commercial dairy herds.	Nitrogen	34-42	Weaning weight-maternal milk	Bos taurus	24-28
12927873-5	2003	Incorporation of a B-ring pyridyl nitrogen either at the 3- or 4-position also elevated CFTR activity, but the influence of this structural modification was not as uniform as the influence of benzannulation.	Nitrogen	34-42	CF transmembrane conductance regulator	Homo sapiens	88-92
14719272-3	2003	The release of NO3(-)-N is most marked, the increasing concentration of NO3(-)-N, NH4(+)-N, NO2(-)-N and DIP reach in turns: 11.869 mumol.L-1, 2.1713 mumol.L-1, 0.2 mumol.L-1, 0.02 mumol.L-1.	Nitrogen	18-23	NBL1, DAN family BMP antagonist	Homo sapiens	72-75
14719272-3	2003	The release of NO3(-)-N is most marked, the increasing concentration of NO3(-)-N, NH4(+)-N, NO2(-)-N and DIP reach in turns: 11.869 mumol.L-1, 2.1713 mumol.L-1, 0.2 mumol.L-1, 0.02 mumol.L-1.	Nitrogen	75-80	NBL1, DAN family BMP antagonist	Homo sapiens	15-18
14562914-1	2003	The nitrogen-modified lignocelluloses(NML) produced under oxic ammoniation was metabolized by white rot fungus, NH4(+) -N was released, NO3(-) -N concentration was decreased and total nitrogen loss was blocked within incubation period.	Nitrogen	4-12	NBL1, DAN family BMP antagonist	Homo sapiens	136-142
12946153-1	2003	This paper describes a highly efficient synthetic method of symmetrical 1,3-diynes from 1-iodoalkynes in the presence of 4 mol % Pd(PPh(3))(4) in DMF at room temperature under a nitrogen atmosphere without any use of additives and other metals.	Nitrogen	178-186	caveolin 1	Homo sapiens	132-138
14499178-11	2003	These results suggest that N-methylation of anthracyclines circumvents resistance by diminishing drug transport by P-gp in MDR-positive cells.	Nitrogen	27-28	ATP binding cassette subfamily B member 1	Homo sapiens	115-119
12773476-2	2003	We have previously shown that in living cells N-glycosylation of the prion protein (PrP) is also abolished when its Asn-Ile-Thr and Asn-Phe-Thr sequons are less than 60 residues from the C-terminus (Walmsley and Hooper [2003] Biochemical Journal, 370, 351-355).	Nitrogen	46-47	prion protein	Homo sapiens	84-87
14507038-1	2003	A retrospective observational study was conducted using data from Dairy Herd Improvement monthly tests to investigate the association between milk urea nitrogen (MUN) concentration and milk yield, milk protein, milk fat percentage, SCC, and parity for commercial Holstein and Jersey herds in Utah, Idaho, and Montana.	Nitrogen	152-160	Weaning weight-maternal milk	Bos taurus	142-146
14507038-1	2003	A retrospective observational study was conducted using data from Dairy Herd Improvement monthly tests to investigate the association between milk urea nitrogen (MUN) concentration and milk yield, milk protein, milk fat percentage, SCC, and parity for commercial Holstein and Jersey herds in Utah, Idaho, and Montana.	Nitrogen	152-160	Weaning weight-maternal milk	Bos taurus	185-189
14507038-1	2003	A retrospective observational study was conducted using data from Dairy Herd Improvement monthly tests to investigate the association between milk urea nitrogen (MUN) concentration and milk yield, milk protein, milk fat percentage, SCC, and parity for commercial Holstein and Jersey herds in Utah, Idaho, and Montana.	Nitrogen	152-160	Weaning weight-maternal milk	Bos taurus	185-189
15969098-2	2003	Assimilatory NADH: nitrate reductase (NR, EC 1.6.6.1), a complex Mo-pterin-, cytochrome b(557)- and FAD-containing protein, catalyzes the regulated and rate-limiting step in the utilization of inorganic nitrogen by higher plants.	Nitrogen	203-211	nitrate reductase [NADH]	Solanum lycopersicum	19-36
12784118-9	2003	Finally, NS-398 reduced Ca2+-independent inducible nitric oxide synthase (iNOS, NOS-2) activity and lowered the stress-induced accumulation of NO metabolite levels in cortex.	Nitrogen	9-11	nitric oxide synthase 2	Rattus norvegicus	41-72
12784118-9	2003	Finally, NS-398 reduced Ca2+-independent inducible nitric oxide synthase (iNOS, NOS-2) activity and lowered the stress-induced accumulation of NO metabolite levels in cortex.	Nitrogen	9-11	nitric oxide synthase 2	Rattus norvegicus	74-78
12784118-9	2003	Finally, NS-398 reduced Ca2+-independent inducible nitric oxide synthase (iNOS, NOS-2) activity and lowered the stress-induced accumulation of NO metabolite levels in cortex.	Nitrogen	9-11	nitric oxide synthase 2	Rattus norvegicus	80-85
12885234-3	2003	These molecules typically showed inhibition constants in the range of 150-425 nM against thrombin and 360-965 nM against trypsin, even though some bulky derivatives, such as N,N-diphenylcarbamoylguanidine/aminoguanidine and their congeners, showed much stronger thrombin inhibitory activity, with inhibition constants in the range of 24-42 nM.	Nitrogen	174-175	coagulation factor II, thrombin	Homo sapiens	262-270
12901863-0	2003	Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells.	Nitrogen	29-30	ATP binding cassette subfamily C member 6	Homo sapiens	54-59
12901863-5	2003	Our results indicate that Asn15, which is located in the extracellular N-terminal region of human ABCC6, is the only N-glycosylation site in this protein.	Nitrogen	71-72	ATP binding cassette subfamily C member 6	Homo sapiens	98-103
12913071-8	2003	Pulse-chase experiments demonstrate that during maturation wolframin is N-glycosylated but lacks proteolytical processing.	Nitrogen	72-73	wolframin ER transmembrane glycoprotein	Homo sapiens	59-68
12913071-9	2003	Moreover, N-glycosylation appears to be essential for the biogenesis and stability of wolframin.	Nitrogen	10-11	wolframin ER transmembrane glycoprotein	Homo sapiens	86-95
14655355-7	2003	The more nitrogen used, the more NO3(-)-N accumulated in soil profile.	Nitrogen	9-17	NBL1, DAN family BMP antagonist	Homo sapiens	33-36
12771134-0	2003	Dopamine prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide: is nitrotyrosine formation an early step in dopamine neuronal damage?	Nitrogen	73-81	tyrosine hydroxylase	Homo sapiens	31-51
12936704-0	2003	Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes.	Nitrogen	92-93	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	18-24
12936704-0	2003	Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes.	Nitrogen	92-93	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	49-64
12936704-2	2003	The aim was to identify the cytochrome P450 (CYP) enzymes responsible for the N-demethylation of morphine in vitro.	Nitrogen	78-79	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	28-43
12936704-2	2003	The aim was to identify the cytochrome P450 (CYP) enzymes responsible for the N-demethylation of morphine in vitro.	Nitrogen	78-79	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	45-48
12967198-2	2003	It is metabolized in humans through the N-dealkylation pathway, to desethylchloroquine (DCQ) and bisdesethylchloroquine (BDCQ), by cytochrome P450 (CYP).	Nitrogen	40-41	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	131-146
12967198-2	2003	It is metabolized in humans through the N-dealkylation pathway, to desethylchloroquine (DCQ) and bisdesethylchloroquine (BDCQ), by cytochrome P450 (CYP).	Nitrogen	40-41	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	148-151
14655355-8	2003	Under the same nitrogen application rate, NO3(-)-N accumulation might decrease with increasing P application.	Nitrogen	15-23	NBL1, DAN family BMP antagonist	Homo sapiens	42-45
12906060-0	2003	Effect of dietary carbohydrate composition and availability on utilization of ruminal ammonia nitrogen for milk protein synthesis in dairy cows.	Nitrogen	94-102	casein beta	Bos taurus	107-119
12893130-1	2003	Tramadol is an opioid drug metabolised in phase I by cytochrome P450 (CYP) enzymes, of which CYP2D6 is mainly responsible for the O-demethylation of tramadol, but is not involved in N-demethylation.	Nitrogen	182-183	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	70-73
12860388-1	2003	Dur3 encodes the yeast plasma membrane urea transporter and Deltadur3 mutants are unable to grow on media containing low concentrations of urea as sole nitrogen source.	Nitrogen	152-160	Dur3p	Saccharomyces cerevisiae S288C	0-4
12853635-4	2003	Intensity changes were observed for amide resonances in the (1)H-(15)N correlation spectrum of uniformly (15)N-labeled hRPA70(1-326) after the addition of unlabeled XPA-MBD.	Nitrogen	68-70	XPA, DNA damage recognition and repair factor	Homo sapiens	165-168
12906060-12	2003	The results suggested that, compared to diets containing higher levels of ruminally fermentable starch, diets providing higher concentration of ruminally fermentable fiber may enhance transfer of ruminal ammonia and microbial N into milk protein.	Nitrogen	226-227	casein beta	Bos taurus	233-245
12887896-1	2003	Oligosaccharyltransferase (OST) is an integral membrane protein that catalyzes N-linked glycosylation of nascent proteins in the lumen of the endoplasmic reticulum.	Nitrogen	79-80	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	0-25
12879861-12	2003	Thus N-glycosylation, and particularly terminal sialylation, affected Kv1.l gating properties both by altering the surface potential sensed by the channel"s activation gating machinery and by modifying conformational changes regulating cooperative subunit interactions during activation and inactivation.	Nitrogen	5-6	potassium voltage-gated channel subfamily A member 5	Rattus norvegicus	70-73
12828642-5	2003	Arg82p and Kcs1p are required for activation of NCR-regulated genes in response to nitrogen availability, mainly through Nil1p, and for repression of PHO genes by phosphate.	Nitrogen	83-91	inositol polyphosphate kinase KCS1	Saccharomyces cerevisiae S288C	11-16
12843317-8	2003	We have also shown that cochlin is N-glycosylated in its mature secreted form.	Nitrogen	35-36	cochlin	Homo sapiens	24-31
12943812-8	2003	Reduced viability following IR and nitrogen starvation was observed among strains deleted for CCR4 or DHH1 because of a defect in G1 to S phase checkpoint transition.	Nitrogen	35-43	DExD/H-box ATP-dependent RNA helicase DHH1	Saccharomyces cerevisiae S288C	102-106
12943812-9	2003	Lethality following nitrogen starvation and IR was partially rescued in dhh1Delta strains by expressing the human ortholog of DHH1 (DDX6) which has been identified as a breakpoint oncogene.T CONCLUSIONS: hese results suggest that BRCA1 may promote genomic stability in human cells by interacting with the highly conserved ortholog of DHH1 (DDX6) to properly activate G1/S checkpoint arrest following DNA damage.	Nitrogen	20-28	DExD/H-box ATP-dependent RNA helicase DHH1	Saccharomyces cerevisiae S288C	126-130
12887896-1	2003	Oligosaccharyltransferase (OST) is an integral membrane protein that catalyzes N-linked glycosylation of nascent proteins in the lumen of the endoplasmic reticulum.	Nitrogen	79-80	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
12854171-0	2003	Effects of carbon dioxide and nitrogen on adhesive growth and expressions of E-cadherin and VEGF of human colon cancer cell CCL-228.	Nitrogen	30-38	cadherin 1	Homo sapiens	77-87
12815173-6	2003	The in vitro N-acetylation of p-aminosalicylate was detected at significant levels in liver and kidney cytosols from either wild-type inbred "rapid acetylator" C57BL/6 mice or from outbred CD-1 mice possessing homozygous rapid, heterozygous, or homozygous "slow acetylator" Nat2 genotypes.	Nitrogen	13-14	N-acetyltransferase 2 (arylamine N-acetyltransferase)	Mus musculus	274-278
12837871-9	2003	Higher cTnT also correlated with higher serum creatine kinase-MB mass, lower serum parathyroid hormone, higher blood urea nitrogen and bicarbonate levels, and the use of diuretics, but not with higher cardiac troponin I.	Nitrogen	122-130	troponin T2, cardiac type	Homo sapiens	7-11
12854171-0	2003	Effects of carbon dioxide and nitrogen on adhesive growth and expressions of E-cadherin and VEGF of human colon cancer cell CCL-228.	Nitrogen	30-38	vascular endothelial growth factor A	Homo sapiens	92-96
12854171-4	2003	RESULTS: After 60 min of carbon dioxide and longer time of nitrogen treatment, the suspended cells increased and the expression of e-cadherin decreased while the expression of VEGF was enhanced significantly.	Nitrogen	59-67	cadherin 1	Homo sapiens	131-141
12854171-4	2003	RESULTS: After 60 min of carbon dioxide and longer time of nitrogen treatment, the suspended cells increased and the expression of e-cadherin decreased while the expression of VEGF was enhanced significantly.	Nitrogen	59-67	vascular endothelial growth factor A	Homo sapiens	176-180
12801601-4	2003	Pain and analgesia have been the best studied, and administration of OFQ/N is reported to have no effect, to produce hyperalgesia, analgesia or anti-hyperalgesia.	Nitrogen	73-74	prepronociceptin	Homo sapiens	69-72
12773155-1	2003	Cytochrome c " (cyt c ") is found in the periplasmic space of denitrifying bacteria where it is thought to mediate the transfer of NO between the nitrogen-cycle enzymes dissimilatory nitrite reductase and nitric oxide reductase.	Nitrogen	146-154	cytochrome c, somatic	Homo sapiens	0-12
12945785-4	2003	A special catalytic function is proposed for decomposition of the tetrahedral addition intermediate (T+/-) via k3 whereby the catalytic imidazole interacts electrophilically with the leaving phenolate ion and removes a proton from the nitrogen in the rate limiting step with subsequent non-rate limiting ArO-C bond fission.	Nitrogen	235-243	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	304-307
12829373-1	2003	N-glycans of the mouse glycoprotein HSA and its human analogue CD24 from lymphoblastoma, neuroblastoma and astrocytoma cell lines as well as from mouse brain homogenate were analysed and compared to each other and to the N-glycosylation pattern of total glycoproteins from mouse and human brain.	Nitrogen	0-1	CD24 molecule	Homo sapiens	63-67
12868524-3	2003	The process was capable of completely denitrifying the NOx- -N (the sum of NO2- -N and NO3- -N) in the nitrified recycle, resulting in an NOx- -N concentration of less than 1.0 mg l(-1) N in the anoxic zones.	Nitrogen	55-56	NBL1, DAN family BMP antagonist	Homo sapiens	87-90
12877809-10	2003	There is a deletion of an N-linked glycosylation site at Asn342 in the tree shrew CETP protein that may participate in the removal of peripheral cholesterol and cholesteryl ester by increasing its activity of transferring cholesteryl ester.	Nitrogen	26-27	cholesteryl ester transfer protein	Oryctolagus cuniculus	82-86
12776183-2	2003	N-glycosylation is initiated by the oligosaccharyl transferase complex and O-mannosylation is initiated by distinct O-mannosyltransferase complexes of the protein mannosyl transferase Pmt1/Pmt2 and Pmt4 families.	Nitrogen	0-1	dolichyl-phosphate-mannose-protein mannosyltransferase PMT1	Saccharomyces cerevisiae S288C	184-188
12776183-2	2003	N-glycosylation is initiated by the oligosaccharyl transferase complex and O-mannosylation is initiated by distinct O-mannosyltransferase complexes of the protein mannosyl transferase Pmt1/Pmt2 and Pmt4 families.	Nitrogen	0-1	dolichyl-phosphate-mannose-protein mannosyltransferase PMT2	Saccharomyces cerevisiae S288C	189-193
12753090-9	2003	Overall these results confirm the pro-oxidant activity of G93A Cu,Zn SOD mutant and, at the same time, suggest a cross-talk between reactive oxygen and nitrogen species via the proteasome pathway.	Nitrogen	152-160	superoxide dismutase 1	Homo sapiens	63-72
12796300-8	2003	Our findings show that perceived nitrogen deprivation triggered by rapamycin treatment and steady-state growth in nitrogen-derepressing conditions are associated with hyperphosphorylation of Put3p and increased PUT1 expression.	Nitrogen	33-41	proline dehydrogenase	Saccharomyces cerevisiae S288C	211-215
12796300-8	2003	Our findings show that perceived nitrogen deprivation triggered by rapamycin treatment and steady-state growth in nitrogen-derepressing conditions are associated with hyperphosphorylation of Put3p and increased PUT1 expression.	Nitrogen	114-122	proline dehydrogenase	Saccharomyces cerevisiae S288C	211-215
12743014-10	2003	Aortic ACE content, measured by autoradiography, directly correlated to the plasma level of urea nitrogen, suggesting that renal failure has an enhancing influence on the vascular renin-angiotensin system.	Nitrogen	97-105	angiotensin I converting enzyme	Rattus norvegicus	7-10
12819638-1	2003	Using Western-blot analysis and enzyme-linked immunosorbent assay (ELISA) of N-deglycosylated samples, we have observed that plasma levels of fibronectin (FN) bearing the alternatively spliced EIIIB segment (EIIIB(+) FN) increase in patients after admission to the intensive-care unit (ICU) for acute major trauma.	Nitrogen	77-78	fibronectin 1	Homo sapiens	142-153
12819638-1	2003	Using Western-blot analysis and enzyme-linked immunosorbent assay (ELISA) of N-deglycosylated samples, we have observed that plasma levels of fibronectin (FN) bearing the alternatively spliced EIIIB segment (EIIIB(+) FN) increase in patients after admission to the intensive-care unit (ICU) for acute major trauma.	Nitrogen	77-78	fibronectin 1	Homo sapiens	155-157
12938735-6	2003	Mice with endowed defences against superoxide or with deficiency in the nNOS and iNOS are protected from MPTP toxicity suggesting that formation of reactive oxygen and nitrogen intermediates both intracellularly and extracellularly contributes to the demise of dopaminergic neurons.	Nitrogen	168-176	nitric oxide synthase 2, inducible	Mus musculus	81-85
12805577-4	2003	Boolean logic was used to model the effect of these carbon/light interactions on three target genes involved in nitrogen assimilation: asparagine synthetase (ASN1 and ASN2) and glutamine synthetase (GLN2).	Nitrogen	112-120	glutamate-ammonia ligase	Homo sapiens	177-197
12738881-0	2003	The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana.	Nitrogen	86-94	glutamate receptor 1.1	Arabidopsis thaliana	13-35
12805621-0	2003	Overexpression of the ASN1 gene enhances nitrogen status in seeds of Arabidopsis.	Nitrogen	41-49	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	22-26
12805621-4	2003	In seeds of the 35S-ASN1 lines, three observations support the notion that the nitrogen status was enhanced: (a) elevations of soluble seed protein contents, (b) elevations of total protein contents from acid-hydrolyzed seeds, and (c) higher tolerance of young seedlings when grown on nitrogen-limiting media.	Nitrogen	79-87	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	20-24
12956537-5	2003	Experiments with various nitrogen supply regimes demonstrated the induction of NRT2.1 expression by nitrate and repression by amino acids.	Nitrogen	25-33	nitrate transporter 2:1	Arabidopsis thaliana	79-83
12738881-0	2003	The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana.	Nitrogen	86-94	glutamate receptor 1.1	Arabidopsis thaliana	37-45
12755619-8	2003	A different N-linked glycosylation pattern was observed in pathological GCDFP-15/PIP as compared with physiological gp17/SABP protein by coupling enzymatic digestion and ProteinChip technology.	Nitrogen	12-13	prolactin induced protein	Homo sapiens	72-80
12738881-3	2003	We used an antisense strategy to demonstrate that the putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of C and N metabolism in Arabidopsis.	Nitrogen	131-132	glutamate receptor 1.1	Arabidopsis thaliana	63-85
12755619-8	2003	A different N-linked glycosylation pattern was observed in pathological GCDFP-15/PIP as compared with physiological gp17/SABP protein by coupling enzymatic digestion and ProteinChip technology.	Nitrogen	12-13	prolactin induced protein	Homo sapiens	81-84
12738881-3	2003	We used an antisense strategy to demonstrate that the putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of C and N metabolism in Arabidopsis.	Nitrogen	131-132	glutamate receptor 1.1	Arabidopsis thaliana	87-95
12726995-3	2003	While it has been established that impairment of N-glycosylation of TPalpha significantly affects ligand binding/intracellular signalling, previous studies did not ascertain whether N-linked glycosylation was critical for ligand binding per se or whether it was required for the intracellular trafficking and the functional expression of TPalpha on the plasma membrane (PM).	Nitrogen	49-50	plasminogen activator, tissue type	Homo sapiens	68-75
12726995-4	2003	In the current study, we investigated the role of N-linked glycosylation in determining the functional expression of TPalpha, by assessment of its ligand binding, G protein coupling and intracellular signalling properties, correlating it with the level of antigenic TPalpha protein expressed on the PM and/or retained intracellularly.	Nitrogen	50-51	plasminogen activator, tissue type	Homo sapiens	117-124
12726995-5	2003	From our data, we conclude that N-glycosylation of either Asn(4) or Asn(16) is required and sufficient for expression of functionally active TPalpha on the PM while the fully non-glycosylated TPalpha(N4,N16-Q4,Q16) is almost completely retained within the endoplasmic reticulum (ER) and remains functionally inactive, failing to associate with its coupling G protein Galpha(q) and, in turn, failing to mediate phospholipase (PL) Cbeta activation.	Nitrogen	32-33	plasminogen activator, tissue type	Homo sapiens	141-148
12726995-5	2003	From our data, we conclude that N-glycosylation of either Asn(4) or Asn(16) is required and sufficient for expression of functionally active TPalpha on the PM while the fully non-glycosylated TPalpha(N4,N16-Q4,Q16) is almost completely retained within the endoplasmic reticulum (ER) and remains functionally inactive, failing to associate with its coupling G protein Galpha(q) and, in turn, failing to mediate phospholipase (PL) Cbeta activation.	Nitrogen	32-33	plasminogen activator, tissue type	Homo sapiens	192-199
12711115-7	2003	However, tumor/normal ratio (T/N ratio) of cten/GAPDH expression was significantly higher in stage II-IV lung cancer (3.113+/-6.493) when compared with stage I lung cancer (1.237+/-1.820, P=0.0316).	Nitrogen	31-32	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	48-53
12713467-1	2003	The regulation of glutamine synthetase (EC 6.3.1.2) from Prochlorococcus was previously shown to exhibit unusual features: it is not upregulated by nitrogen starvation and it is not inactivated by darkness (El Alaoui et al.	Nitrogen	148-156	glutamate-ammonia ligase	Homo sapiens	18-38
12711115-8	2003	T/N ratio of cten/GAPDH expression was significantly higher in T4 lung cancer (4.612+/-9.726) when compared with T1 lung cancer (0.896+/-0.860, P=0.0252), and T2 lung cancer (1.636+/-2.066, P=0.0470), respectively.	Nitrogen	2-3	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	18-23
12588874-6	2003	We found that glucose strongly stimulates O-linked N-acetylglucosaminylation (O-GlcNAcylation) on YY1.	Nitrogen	51-52	YY1 transcription factor	Homo sapiens	98-101
12803082-5	2003	Surprisingly, the excited state decay is not due to twisting about the C-N bond of the ylide but it is caused by buckling of one of the rings as the nitrogen atom changes character from sp2 to sp3 hybridisation.	Nitrogen	149-157	Sp2 transcription factor	Homo sapiens	186-189
12803082-5	2003	Surprisingly, the excited state decay is not due to twisting about the C-N bond of the ylide but it is caused by buckling of one of the rings as the nitrogen atom changes character from sp2 to sp3 hybridisation.	Nitrogen	149-157	Sp3 transcription factor	Homo sapiens	193-196
12892045-6	2003	In all the organs studied, the activities of the enzymes involved in the anabolic nitrogen primary assimilation pathways (nitrate reductase (NR), nitrite reductase (NiR) and glutamine synthetase (GS) soared after that cadmium had been removed.	Nitrogen	82-90	nitrate reductase [NADH]	Solanum lycopersicum	122-139
12529169-7	2003	During growth on a preferred nitrogen source like NH(4)(+), CIS2 expression is repressed through a mechanism involving (at least) the Gln3-binding protein Ure2/GdhCR.	Nitrogen	29-37	glutathione peroxidase	Saccharomyces cerevisiae S288C	155-159
12667607-4	2003	In the alg1 and alg2 mutants, complemented with MPG1 gene, N-glycosylation of invertase was in part restored, to a degree comparable to that of the wild-type control.	Nitrogen	59-60	macrophage expressed 1	Homo sapiens	48-52
12721102-17	2003	The highest intrinsic clearance (V(max)/K(m)) was found for CYP1A subfamily, CYP3A4 and CYP2B6 in the case of 5- sulphoxidation, and for CYP2C19, CYP1A subfamily and CYP2B6 in the case of N-demethylation.	Nitrogen	188-189	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	77-83
12721102-21	2003	Regarding the relative expression of various CYPs in human liver, the obtained results indicate that CYP1A2 and CYP3A4 are the main isoforms responsible for 5-sulphoxidation, while CYP1A2 and CYP2C19 are the basic isoforms that catalyse N-demethylation of promazine in human liver.	Nitrogen	237-238	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	112-118
12697062-11	2003	CONCLUSION: We have cloned the rabbit MYOC cDNA and determined that rabbit myocilin is secreted but not N-linked glycosylated.	Nitrogen	2-3	myocilin	Oryctolagus cuniculus	38-42
12697062-11	2003	CONCLUSION: We have cloned the rabbit MYOC cDNA and determined that rabbit myocilin is secreted but not N-linked glycosylated.	Nitrogen	2-3	myocilin	Oryctolagus cuniculus	75-83
12605602-1	2003	We used a N-biotinylated peptide analog of the C-terminal domain of the tumor suppressor protein, p21cip1/waf1 to elucidate peptide/protein interacting partners.	Nitrogen	10-11	cyclin dependent kinase inhibitor 1A	Homo sapiens	98-105
12632065-8	2003	In contrast, addition of 50 micro M NS-398 to COX-2 non-expressing PLC/PRF/5 cells resulted in only a mild reduction of cell proliferation.	Nitrogen	36-38	prostaglandin-endoperoxide synthase 2	Homo sapiens	46-51
12605602-1	2003	We used a N-biotinylated peptide analog of the C-terminal domain of the tumor suppressor protein, p21cip1/waf1 to elucidate peptide/protein interacting partners.	Nitrogen	10-11	cyclin dependent kinase inhibitor 1A	Homo sapiens	106-110
12605602-8	2003	The use of N-biotinylated peptide derived from the C-terminal domain of p21cip1/waf1 protein in proteomic analysis exemplified here suggests that peptides obtained from intracellular functional screens could also potentially serve as efficient baits to discover new drug targets.	Nitrogen	11-12	cyclin dependent kinase inhibitor 1A	Homo sapiens	72-79
12605602-8	2003	The use of N-biotinylated peptide derived from the C-terminal domain of p21cip1/waf1 protein in proteomic analysis exemplified here suggests that peptides obtained from intracellular functional screens could also potentially serve as efficient baits to discover new drug targets.	Nitrogen	11-12	cyclin dependent kinase inhibitor 1A	Homo sapiens	80-84
12633748-8	2003	By varying the n-alkyl chain length, thereby modifying the surfactant properties of the ATX-C(x) derivatives, cell killing in relation to the accumulation of ATX-C(x) derivatives at the gas/solution interface of cavitation bubbles was determined.	Nitrogen	8-9	ectonucleotide pyrophosphatase/phosphodiesterase 2	Homo sapiens	88-91
12525494-7	2003	However, for only SER33, and not SER3, expression was regulated in relation to the available nitrogen source in a coordinated fashion with SER1 and SER2.	Nitrogen	93-101	phosphoglycerate dehydrogenase SER3	Saccharomyces cerevisiae S288C	18-22
12633748-8	2003	By varying the n-alkyl chain length, thereby modifying the surfactant properties of the ATX-C(x) derivatives, cell killing in relation to the accumulation of ATX-C(x) derivatives at the gas/solution interface of cavitation bubbles was determined.	Nitrogen	8-9	ectonucleotide pyrophosphatase/phosphodiesterase 2	Homo sapiens	158-161
12703484-5	2003	The predicted IL-8 peptide had one potential N-linked glycosylation site (Asn-72-Thr-74) that is not conserved in other vertebrates.	Nitrogen	45-46	C-X-C motif chemokine ligand 8	Homo sapiens	14-18
12620851-3	2003	A pro3 ure2 strain expressing a PGK1 promoter-driven PUT2 allele encoding Delta(1)-pyrroline-5-carboxylate dehydrogenase lacking a mitochondrial targeting sequence produced significant cytoplasmic activity, accumulated twice as much intracellular glutamate, and produced twice as much cell mass as the parent when grown anaerobically on limiting arginine as sole nitrogen source.	Nitrogen	363-371	pyrroline-5-carboxylate reductase	Saccharomyces cerevisiae S288C	2-6
12606584-1	2003	The [URE3] phenotype in Saccharomyces cerevisiae is caused by the inactive, altered (prion) form of the Ure2 protein (Ure2p), a regulator of nitrogen catabolism.	Nitrogen	141-149	glutathione peroxidase	Saccharomyces cerevisiae S288C	104-108
12606584-1	2003	The [URE3] phenotype in Saccharomyces cerevisiae is caused by the inactive, altered (prion) form of the Ure2 protein (Ure2p), a regulator of nitrogen catabolism.	Nitrogen	141-149	glutathione peroxidase	Saccharomyces cerevisiae S288C	118-123
12606584-2	2003	Ure2p has two functional domains: an N-terminal domain necessary and sufficient for prion propagation and a C-terminal domain responsible for nitrogen regulation.	Nitrogen	142-150	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
12723939-5	2003	These compounds also inhibited the production of NO and H2O2 induced by TNF-alpha, which suggests that the inhibition of ICAM-1 expression by the three compounds may be due to the modulated production of the reactive oxygen/nitrogen components.	Nitrogen	224-232	tumor necrosis factor	Homo sapiens	72-81
12604705-9	2003	We hypothesize the N-n-octyl group on the pyridinium nitrogen of NONI facilitates brain entry via the BBB choline transporter.	Nitrogen	53-61	solute carrier family 6 member 8	Rattus norvegicus	106-125
12464625-1	2003	Calreticulin is a molecular chaperone found in the endoplasmic reticulum in eukaryotes, and its interaction with N-glycosylated polypeptides is mediated by the glycan Glc(1)Man(7-9)GlcNAc(2) present on the target glycoproteins.	Nitrogen	113-114	calreticulin	Homo sapiens	0-12
12584318-4	2003	55% identity) murine paralog (mASCT1; gene name, SLC1A4) mediates infections specifically of BaEV and HERV-W, and that N-deglycosylation of mASCT1 activates it as a receptor for all viruses of this interference group.	Nitrogen	119-120	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	Mus musculus	140-146
12632526-6	2003	RESULTS: The positive nitrogen balance in BCAA group occurred two days earlier than that in AA group.	Nitrogen	22-30	AT-rich interaction domain 4B	Homo sapiens	42-46
12586388-1	2003	The rat serotonin transporter (rSERT) is an N-glycosylated integral membrane protein with 12 transmembrane regions; the N-glycans improve the ability of the SERT polypeptide chain to fold into a functional transporter, but they are not required for the transmembrane transport of serotonin per se.	Nitrogen	44-45	solute carrier family 6 member 4	Rattus norvegicus	8-29
12460122-1	2003	Cell-specific differences in the utilization of the two N-glycosylation sequons (Asn180-Ile-Thr and Asn196-Phe-Thr) of the prion protein (PrP) have been proposed to influence the aetiology of the neurodegenerative prion diseases.	Nitrogen	56-57	prion protein	Homo sapiens	138-141
12460122-2	2003	As the N-glycosylation of PrP is ablated by deletion of the C-terminal glycosyl-phosphatidylinositol (GPI) anchor signal sequence, we have investigated the determinants for PrP sequon utilization in human neuronal cells using the novel approach of restoring N-glycosylation to secreted forms of PrP lacking a GPI anchor.	Nitrogen	7-8	prion protein	Homo sapiens	26-29
12460122-2	2003	As the N-glycosylation of PrP is ablated by deletion of the C-terminal glycosyl-phosphatidylinositol (GPI) anchor signal sequence, we have investigated the determinants for PrP sequon utilization in human neuronal cells using the novel approach of restoring N-glycosylation to secreted forms of PrP lacking a GPI anchor.	Nitrogen	258-259	prion protein	Homo sapiens	26-29
12586388-1	2003	The rat serotonin transporter (rSERT) is an N-glycosylated integral membrane protein with 12 transmembrane regions; the N-glycans improve the ability of the SERT polypeptide chain to fold into a functional transporter, but they are not required for the transmembrane transport of serotonin per se.	Nitrogen	44-45	solute carrier family 6 member 4	Rattus norvegicus	31-36
12586388-1	2003	The rat serotonin transporter (rSERT) is an N-glycosylated integral membrane protein with 12 transmembrane regions; the N-glycans improve the ability of the SERT polypeptide chain to fold into a functional transporter, but they are not required for the transmembrane transport of serotonin per se.	Nitrogen	44-45	solute carrier family 6 member 4	Rattus norvegicus	32-36
12586388-10	2003	In addition, the cell lines MEL-SERT, Imi270 and T-REx-SERT all expressed fully N-glycosylated SERT and no unglycosylated inactive protein, in contrast to the baculovirus expression system where the vast majority of expressed SERT was unglycosylated and nonfunctional.	Nitrogen	80-81	solute carrier family 6 member 4	Homo sapiens	55-59
12565836-0	2003	Critical role of N-terminal N-glycosylation for proper folding of the human formyl peptide receptor.	Nitrogen	17-18	formyl peptide receptor 1	Homo sapiens	76-99
12565836-1	2003	The human formyl peptide receptor (FPR) is N-glycosylated and activates phagocytes via G(i)-proteins.	Nitrogen	43-44	formyl peptide receptor 1	Homo sapiens	10-33
12586388-10	2003	In addition, the cell lines MEL-SERT, Imi270 and T-REx-SERT all expressed fully N-glycosylated SERT and no unglycosylated inactive protein, in contrast to the baculovirus expression system where the vast majority of expressed SERT was unglycosylated and nonfunctional.	Nitrogen	80-81	solute carrier family 6 member 4	Homo sapiens	55-59
12565836-1	2003	The human formyl peptide receptor (FPR) is N-glycosylated and activates phagocytes via G(i)-proteins.	Nitrogen	43-44	formyl peptide receptor 1	Homo sapiens	35-38
12565836-3	2003	The aim of our study was to analyze the role of N-glycosylation in FPR function.	Nitrogen	48-49	formyl peptide receptor 1	Homo sapiens	67-70
12586388-10	2003	In addition, the cell lines MEL-SERT, Imi270 and T-REx-SERT all expressed fully N-glycosylated SERT and no unglycosylated inactive protein, in contrast to the baculovirus expression system where the vast majority of expressed SERT was unglycosylated and nonfunctional.	Nitrogen	80-81	solute carrier family 6 member 4	Homo sapiens	55-59
12565836-7	2003	Our data indicate that N-glycosylation of N-terminal Asn4 and Asn10 but not of Asn179 in the second extracellular loop is essential for proper folding and, hence, function of FPR.	Nitrogen	23-24	formyl peptide receptor 1	Homo sapiens	175-178
12564927-1	2003	Human cytochrome P450 (P450) 2D6 is an important enzyme involved in the metabolism of drugs, many of which are amines or contain other basic nitrogen atoms.	Nitrogen	141-149	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	6-32
12540786-10	2003	Significant increases in plasma renin activity and plasma aldosterone levels were only observed in patients in the N + S group (P &lt;.01).	Nitrogen	115-120	renin	Homo sapiens	32-37
12446689-2	2003	CYP2D6 substrates typically contain a basic nitrogen atom, and the active-site residue Asp-301 has been implicated in substrate recognition through electrostatic interactions.	Nitrogen	44-52	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	0-6
12446689-12	2003	Neutralizing both Glu-216 and Asp-301 thus effectively alters substrate recognition illustrating the central role of the negative charges provided by both residues in defining the specificity of CYP2D6 toward substrates containing a basic nitrogen.	Nitrogen	239-247	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	195-201
12610742-8	2003	RESULTS: Of the identified components in grapefruit peel, only epoxybergamottin demonstrated a concentration-dependent inhibition of the CYP3A4-mediated N-demethylation of diltiazem.	Nitrogen	153-154	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	137-143
12557135-9	2003	RESULTS: Treatment with GH increased intestinal absorption of energy (15% +/- 5%, P &lt; 0.002), nitrogen (14% +/- 6%, P &lt; 0.04), carbohydrates (10% +/- 4%, P &lt; 0.04), and fat (12% +/- 8%, NS).	Nitrogen	97-105	growth hormone 1	Homo sapiens	24-26
12557135-9	2003	RESULTS: Treatment with GH increased intestinal absorption of energy (15% +/- 5%, P &lt; 0.002), nitrogen (14% +/- 6%, P &lt; 0.04), carbohydrates (10% +/- 4%, P &lt; 0.04), and fat (12% +/- 8%, NS).	Nitrogen	195-197	growth hormone 1	Homo sapiens	24-26
12486718-2	2003	Leghemoglobin serves an additional role as an oxygen scavenger to prevent inhibition of nitrogen fixation.	Nitrogen	88-96	leghemoglobin A	Glycine max	0-13
12610998-2	2003	The compound (ButO)3W identical to N serves to exchange the nitrogen atoms between nitriles (MeC identical to N and PhC identical to N), itself and (ButO)3Mo identical to N in solution at room temperature.	Nitrogen	60-68	C-C motif chemokine ligand 28	Homo sapiens	93-96
12519063-5	2003	It is known that acidic functionality originating from the alpha-nitrogen of pTyr residues or from the alpha-position of P0 pTyr mimetics not only increases binding affinity of peptides to Grb2 SH2 domains in extracellular assays but also enhances potency in cell-based systems.	Nitrogen	65-73	growth factor receptor bound protein 2	Homo sapiens	189-193
12517972-10	2003	Indo, NS-398, Flur, and 15d-PGJ(2), but not WY-14643, induced transcriptional activity of a COX-2 reporter construct containing the peroxisome proliferator response element (PPRE) on their own and enhanced the effect of IL-1beta, but had no effect on a COX-2 reporter construct lacking the PPRE.	Nitrogen	6-8	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	92-97
12517972-10	2003	Indo, NS-398, Flur, and 15d-PGJ(2), but not WY-14643, induced transcriptional activity of a COX-2 reporter construct containing the peroxisome proliferator response element (PPRE) on their own and enhanced the effect of IL-1beta, but had no effect on a COX-2 reporter construct lacking the PPRE.	Nitrogen	6-8	interleukin 1 beta	Homo sapiens	220-228
12517972-10	2003	Indo, NS-398, Flur, and 15d-PGJ(2), but not WY-14643, induced transcriptional activity of a COX-2 reporter construct containing the peroxisome proliferator response element (PPRE) on their own and enhanced the effect of IL-1beta, but had no effect on a COX-2 reporter construct lacking the PPRE.	Nitrogen	6-8	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	253-258
12489124-1	2003	The role of Gln3p, Nil1p, Dal80p and Ure2p in the nitrogen regulation of ASP3, which codes for the periplasmic Saccharomyces cerevisiae asparaginase II, was investigated.	Nitrogen	50-58	glutathione peroxidase	Saccharomyces cerevisiae S288C	37-42
12890931-6	2003	Previous study data reveal that serum insulin-like growth factor I (IGF-I) concentration is positively correlated with protein intake, and nitrogen retention, in turn, is positively correlated with serum IGF-I concentration.	Nitrogen	139-147	insulin like growth factor 1	Homo sapiens	204-209
12502352-4	2003	The nitrogen-containing homobivalent ligands 3e,g and the sulfur-containing 3h validated the hypothesis of extra sites of interaction in the AChE and BuChE active site gorges.	Nitrogen	4-12	acetylcholinesterase (Cartwright blood group)	Homo sapiens	141-145
14606931-12	2003	Tolterodine is metabolised via CYP2D6 to the active metabolite 5-hydroxymethyl-tolterodine and via CYP3A to N-dealkylated metabolites.	Nitrogen	108-109	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	99-104
14642531-4	2003	This polarity did not correlate with glycosylation, as IL-8 and MIC-1 are both N-glycosylated, but were sorted to opposite sides of the cell.	Nitrogen	79-80	C-X-C motif chemokine ligand 8	Homo sapiens	55-59
12656349-7	2003	The data from these two methods were similar, indicating that all sulfate groups at 2-O, 6-O and N- in heparin were required for the binding to aFGF; and that their contribution to the binding was in the order 2-O, N- and 6-O-sulfate group.	Nitrogen	97-98	fibroblast growth factor 1	Homo sapiens	144-148
12548404-0	2003	Expression of the peptide transporter hPepT1 in human colon: a potential route for colonic protein nitrogen and drug absorption.	Nitrogen	99-107	solute carrier family 15 member 1	Homo sapiens	38-44
12548404-8	2003	We conclude that distal regions of the bowel express hPepT1, which may provide a mechanism for colonic protein-nitrogen absorption and for absorption of therapeutically important peptidomimetic drugs.	Nitrogen	111-119	solute carrier family 15 member 1	Homo sapiens	53-59
12563619-1	2003	OBJECTIVES: Normalized protein nitrogen appearance (nPNA), also known as protein catabolic rate (nPCR), reflects the daily protein intake in maintenance hemodialysis (MHD) patients.	Nitrogen	31-39	nasopharyngeal carcinoma-related protein	Homo sapiens	97-101
12943552-3	2003	The influence of N-glycosylation on AtXylT activity has been evaluated using either tunicamycin or mutagenesis of potential N-glycosylation sites.	Nitrogen	17-18	beta-1,2-xylosyltransferase	Arabidopsis thaliana	36-42
12943552-3	2003	The influence of N-glycosylation on AtXylT activity has been evaluated using either tunicamycin or mutagenesis of potential N-glycosylation sites.	Nitrogen	124-125	beta-1,2-xylosyltransferase	Arabidopsis thaliana	36-42
12943552-4	2003	AtXylT is glycosylated on two of its three potential N-glycosylation sites (Asn51, Asn301, Asn478) and the occupancy of at least one of these two sites (Asn51 and Asn301) is necessary for AtXylT stability and activity.	Nitrogen	53-54	beta-1,2-xylosyltransferase	Arabidopsis thaliana	0-6
12493841-4	2003	The HSQC spectrum of (15)N-labeled CR is similar to the overlaid spectra of individual (15)N-labeled CR fragments (CR I-II and CR III-VI), also suggesting that these regions do not interact within intact CR.	Nitrogen	25-26	calbindin 2	Homo sapiens	35-37
12493841-4	2003	The HSQC spectrum of (15)N-labeled CR is similar to the overlaid spectra of individual (15)N-labeled CR fragments (CR I-II and CR III-VI), also suggesting that these regions do not interact within intact CR.	Nitrogen	91-92	calbindin 2	Homo sapiens	101-103
13678233-1	2003	Green tea extract (EFLA85942) is able to induce specifically the neutral endopeptidase (NEP) activity and to inhibit the proliferation of SK-N-SH cells; the angiotensin-converting enzyme (ACE) activity is not influenced under the same conditions.	Nitrogen	88-89	membrane metalloendopeptidase	Homo sapiens	65-86
12493841-4	2003	The HSQC spectrum of (15)N-labeled CR is similar to the overlaid spectra of individual (15)N-labeled CR fragments (CR I-II and CR III-VI), also suggesting that these regions do not interact within intact CR.	Nitrogen	91-92	calbindin 2	Homo sapiens	101-103
12519691-10	2003	However, other cytochrome P450 enzymes (CYP2E1 and CYP2B6) also appear to play a role in the N-oxidation of this drug.	Nitrogen	93-94	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	40-46
12576159-3	2003	Of various inorganic nitrogen sources, the highest yields of Cry11Aa and Cry4Ba proteins were obtained on (NH(4))(2)HPO(4).	Nitrogen	21-29	BT8	Bacillus thuringiensis serovar israelensis	73-79
12505283-5	2002	For example, oxyradical overload diseases such as Wilson disease and hemochromatosis result in the generation of oxygen/nitrogen species that can cause mutations in the p53 tumor suppressor gene.	Nitrogen	120-128	tumor protein p53	Homo sapiens	169-172
12536789-1	2002	CoII[N(CN)2]2(H2BiIm)2, 1, and [CoII[N(CN)2](H2BiIm)2]Cl, 2 (H2BiIm = 2,2"-biimidazole) have been structurally, spectroscopically, and magnetically characterized with both containing dicyanamides bound in unprecedented manners; namely, solely via the amide nitrogen for 1, and via an imide N forming 1-D helical chains for 2.	Nitrogen	257-265	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	0-4
12433806-3	2002	Kinetics evidence is presented that the N-depropylation of (-)-OSU6162 in human hepatic microsomes is mediated by multiple cytochrome p450 (p450) enzymes, in particular CYP2D6.	Nitrogen	40-41	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	169-175
12444757-0	2002	Interligand interactions controlling the mu-N7,N9-metal bonding of adenine (AdeH) to the N-benzyliminodiacetato(2-) copper(II) chelate and promoting the N9 versus N3 tautomeric proton transfer: molecular and crystal structure of [Cu2(NBzIDA)(2)(H2O)(2)(mu-N7,N9-Ade(N3)H)].(3)H2O.	Nitrogen	44-45	adenylosuccinate synthase 2	Homo sapiens	76-80
12177423-2	2002	Ure2p residues 1-65 constitute the prion domain, and the remaining C-terminal portion regulates nitrogen catabolism.	Nitrogen	96-104	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
12177423-4	2002	We find that the normal function of the S. cerevisiae Ure2p in nitrogen regulation is fully complemented by the Ure2p of Candida albicans, Candida glabrata, Candida kefyr, Candida maltosa, Saccharomyces bayanus, and Saccharomyces paradoxus, all of which have high homology in the C-terminal nitrogen regulation domain.	Nitrogen	63-71	glutathione peroxidase	Saccharomyces cerevisiae S288C	54-59
12177423-4	2002	We find that the normal function of the S. cerevisiae Ure2p in nitrogen regulation is fully complemented by the Ure2p of Candida albicans, Candida glabrata, Candida kefyr, Candida maltosa, Saccharomyces bayanus, and Saccharomyces paradoxus, all of which have high homology in the C-terminal nitrogen regulation domain.	Nitrogen	63-71	glutathione peroxidase	Saccharomyces cerevisiae S288C	112-117
12177423-4	2002	We find that the normal function of the S. cerevisiae Ure2p in nitrogen regulation is fully complemented by the Ure2p of Candida albicans, Candida glabrata, Candida kefyr, Candida maltosa, Saccharomyces bayanus, and Saccharomyces paradoxus, all of which have high homology in the C-terminal nitrogen regulation domain.	Nitrogen	291-299	glutathione peroxidase	Saccharomyces cerevisiae S288C	54-59
12177423-4	2002	We find that the normal function of the S. cerevisiae Ure2p in nitrogen regulation is fully complemented by the Ure2p of Candida albicans, Candida glabrata, Candida kefyr, Candida maltosa, Saccharomyces bayanus, and Saccharomyces paradoxus, all of which have high homology in the C-terminal nitrogen regulation domain.	Nitrogen	291-299	glutathione peroxidase	Saccharomyces cerevisiae S288C	112-117
12433466-4	2002	Oxacephams 41 and 52 with opposite R-configuration at the bridgehead carbon C-5a can be obtained by the alternate methodology based on the alkylation of nitrogen in 4-vinyloxyazetidin-2-one by protected 6-O-triflate 24 or 25, followed by cyclization via intramolecular displacement of the vinyloxy group.	Nitrogen	153-161	complement C5a receptor 1	Homo sapiens	76-80
12481062-4	2002	The AtAMT2 gene was expressed in all organs of Arabidopsis and was subject to nitrogen (N) regulation, at least in roots where expression was partially repressed by high concentrations of ammonium nitrate and derepressed in the absence of external N. Although expression of AtAMT2 in shoots responded little to changes in root N status, transcript levels in leaves declined under high CO(2) conditions.	Nitrogen	78-86	ammonium transporter 2	Arabidopsis thaliana	4-10
12490395-5	2002	xcCAT1 cDNA encodes a protein with a single amino acid change that destroys a conserved N-linked glycosylation site proximal to the Env-binding motif.	Nitrogen	9-10	endogenous retrovirus group W member 1, envelope	Homo sapiens	132-135
12490395-7	2002	Thus, N-glycosylation negatively regulates the receptor activity of rCAT1.	Nitrogen	6-7	transient receptor potential cation channel, subfamily V, member 6	Rattus norvegicus	68-73
12433614-5	2002	VEGF Ca/N ratio increased in response to systemic hypo-oxygenation and nutritional depletion only in elderly patients.	Nitrogen	8-9	vascular endothelial growth factor A	Homo sapiens	0-4
12417748-1	2002	The delivery to the plasma membrane of the general amino acid permease, Gap1p, of Saccharomyces cerevisiae is regulated by the quality of the nitrogen source in the growth medium.	Nitrogen	142-150	amino acid permease GAP1	Saccharomyces cerevisiae S288C	72-77
12417748-2	2002	In an effort to define how different nitrogen sources control Gap1p sorting, we find that mutations in GDH1 and GLN1 that decrease the flux through the glutamate and glutamine synthesis pathways result in increased Gap1p sorting to the plasma membrane.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	62-67
12417748-2	2002	In an effort to define how different nitrogen sources control Gap1p sorting, we find that mutations in GDH1 and GLN1 that decrease the flux through the glutamate and glutamine synthesis pathways result in increased Gap1p sorting to the plasma membrane.	Nitrogen	37-45	amino acid permease GAP1	Saccharomyces cerevisiae S288C	215-220
12223479-5	2002	We investigated here the N-linked glycosylation of the beta4 subunit and its effect on the modulation of the hSlo alpha subunit.	Nitrogen	25-26	adaptor related protein complex 4 subunit beta 1	Homo sapiens	55-60
12223479-8	2002	Enzymatic deglycosylation or mutation of the N-linked glycosylation residues in beta4 converts it to a single lower molecular weight band, even in the presence of the hSlo alpha subunit, suggesting that the beta4 subunit can be present as an immature, core glycosylated form and a mature, highly glycosylated form.	Nitrogen	45-46	adaptor related protein complex 4 subunit beta 1	Homo sapiens	80-85
12223479-8	2002	Enzymatic deglycosylation or mutation of the N-linked glycosylation residues in beta4 converts it to a single lower molecular weight band, even in the presence of the hSlo alpha subunit, suggesting that the beta4 subunit can be present as an immature, core glycosylated form and a mature, highly glycosylated form.	Nitrogen	45-46	adaptor related protein complex 4 subunit beta 1	Homo sapiens	207-212
12223479-13	2002	Taken together, these data show that the pore-forming alpha subunit of the hSlo channel promotes N-linked glycosylation of its auxiliary beta4 subunit, and this in turn influences the modulation of the channel by the beta4 subunit.	Nitrogen	97-98	adaptor related protein complex 4 subunit beta 1	Homo sapiens	137-142
12223479-13	2002	Taken together, these data show that the pore-forming alpha subunit of the hSlo channel promotes N-linked glycosylation of its auxiliary beta4 subunit, and this in turn influences the modulation of the channel by the beta4 subunit.	Nitrogen	97-98	adaptor related protein complex 4 subunit beta 1	Homo sapiens	217-222
12417748-7	2002	Together, these data show that amino acids are a signal for sorting Gap1p to the vacuole and imply that the nitrogen-regulated Gap1p sorting machinery responds to amino acid-like compounds rather than to the overall nutritional status associated with growth on a particular nitrogen source.	Nitrogen	108-116	amino acid permease GAP1	Saccharomyces cerevisiae S288C	68-73
12417748-7	2002	Together, these data show that amino acids are a signal for sorting Gap1p to the vacuole and imply that the nitrogen-regulated Gap1p sorting machinery responds to amino acid-like compounds rather than to the overall nutritional status associated with growth on a particular nitrogen source.	Nitrogen	108-116	amino acid permease GAP1	Saccharomyces cerevisiae S288C	127-132
12417748-7	2002	Together, these data show that amino acids are a signal for sorting Gap1p to the vacuole and imply that the nitrogen-regulated Gap1p sorting machinery responds to amino acid-like compounds rather than to the overall nutritional status associated with growth on a particular nitrogen source.	Nitrogen	274-282	amino acid permease GAP1	Saccharomyces cerevisiae S288C	127-132
12414859-4	2002	VEGF expression, calculated as the percentage of positive cells, was significantly greater (P &lt; 0.0001) in CA (85.3 +/- 2.1) than in APA (56.5 +/- 7.5), CPA (38.5 +/- 7.0), N (33.1 +/- 6.1), and NFA (0.76 +/- 0.6).	Nitrogen	176-177	vascular endothelial growth factor A	Homo sapiens	0-4
12433163-3	2002	There has been little analysis of riparian zones in urban watersheds, despite the fact that urban areas are important sources of NO3- to nitrogen (N)-sensitive coastal waters in many locations.	Nitrogen	137-145	NBL1, DAN family BMP antagonist	Homo sapiens	129-132
12193590-2	2002	The structure of the lipid-A from Rhizobium species Sin-1, a nitrogen-fixing Gram-negative bacterial symbiont of Sesbania, was determined by composition, nuclear magnetic resonance spectroscopic, and mass spectrometric analyses.	Nitrogen	61-69	MAPK associated protein 1	Homo sapiens	52-57
12244275-4	2002	Human recombinant growth hormone (GH) has positive effects on nitrogen balance, and multiple studies have demonstrated improved height and weight in children treated with GH.	Nitrogen	62-70	growth hormone 1	Homo sapiens	18-32
12423667-9	2002	Here, we demonstrate for the first time a role for ERK1/2-mediated GRK2 induction in the development of tolerance to mu agonists, as well as cross-tolerance to OFQ/N.	Nitrogen	164-165	mitogen-activated protein kinase 3	Homo sapiens	51-57
12404797-5	2002	The generation of H2O2 on sonolysis is not significantly affected by the presence of aqueous ClBz while the generation of NO2- and NO3- is inhibited initially due to the presence of ClBz which diffuses into the gas-bubble interfaces and inhibits the interactions between free radicals and nitrogen.	Nitrogen	289-297	NBL1, DAN family BMP antagonist	Homo sapiens	131-134
12366865-7	2002	Mutation abolishing N-glycosylation decreased the efficiency of uPA secretion and increased its aggregation degree.	Nitrogen	20-21	plasminogen activator, urokinase	Homo sapiens	64-67
12487729-7	2002	A sensitive fluorometric technique was employed to quantitate N-alkylPP formation after interaction of individual CYP enzymes with a porphyrinogenic xenobiotic.	Nitrogen	62-63	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	114-117
12487729-9	2002	N-alkylPP formation was found following the interaction of three porphyrinogenic xenobiotics with CYP1A2, 2B1, 2C6, 2C11 and 3A2, in amounts ranging from 0.45 to 0.07 nmol N-alkylPP nmol(-1) CYP.	Nitrogen	0-1	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	98-101
12359240-2	2002	TMEM9 encodes a 183 amino-acid protein that contains an N-terminal signal peptide, a single transmembrane region, three potential N-glycosylation sites, and three conserved cys-rich domains in the N-terminus, but no hitherto known functional domains.	Nitrogen	56-57	transmembrane protein 9	Homo sapiens	0-5
12225948-8	2002	Hypoxia (3% O(2)-5% CO(2)-92% N(2)) for 24 h selectively augmented TGF-beta1-stimulated PGE(2) production and COX-2 induction but had no effect alone.	Nitrogen	30-35	transforming growth factor beta 1	Homo sapiens	67-76
12225948-8	2002	Hypoxia (3% O(2)-5% CO(2)-92% N(2)) for 24 h selectively augmented TGF-beta1-stimulated PGE(2) production and COX-2 induction but had no effect alone.	Nitrogen	30-35	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	110-115
12270821-1	2002	Pseudomonas aeruginosa PAO1 utilizes proline as the sole source of carbon and nitrogen via a bifunctional enzyme (the putA gene product) that has both proline dehydrogenase (EC 1.5.99.8) and pyrroline 5-carboxylate dehydrogenase (EC 1.5.1.12) activities.	Nitrogen	78-86	bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase	Pseudomonas aeruginosa PAO1	118-122
12230987-5	2002	Results indicated that, among these chelating agents, the N-carboxyethyl derivative has the highest affinity towards this set of metal ions, irrespective of the metal, and that it could even compete with transferrin, the main Fe-plasma protein.	Nitrogen	58-59	transferrin	Rattus norvegicus	204-215
12412921-5	2002	Serum IGF-I concentration increased relative to almost undetectable levels (1 ng/mL) of controls to 216 +/- 59 ng/mL at 20 min after IGF-I injection (P &lt; 0.001) and decreased to 12 +/- 6 ng/ mL by 6 h. Serum glucose and nonprotein nitrogen concentrations were significantly decreased for all or most of the 3 h after IGF-I injection, respectively, but only glucose concentration was the same as controls by 6 h. Low serum glucose and nonprotein nitrogen during the first few hours after IGF-I injection may contribute to the inhibition of Ks at 2.5 h, but the mechanisms behind the increased Ks at 6 h are not clear.	Nitrogen	234-242	insulin like growth factor 1	Homo sapiens	6-11
12412921-5	2002	Serum IGF-I concentration increased relative to almost undetectable levels (1 ng/mL) of controls to 216 +/- 59 ng/mL at 20 min after IGF-I injection (P &lt; 0.001) and decreased to 12 +/- 6 ng/ mL by 6 h. Serum glucose and nonprotein nitrogen concentrations were significantly decreased for all or most of the 3 h after IGF-I injection, respectively, but only glucose concentration was the same as controls by 6 h. Low serum glucose and nonprotein nitrogen during the first few hours after IGF-I injection may contribute to the inhibition of Ks at 2.5 h, but the mechanisms behind the increased Ks at 6 h are not clear.	Nitrogen	448-456	insulin like growth factor 1	Homo sapiens	6-11
12399106-9	2002	Furthermore, chronic OFQ/N exposure increased levels of the TH gene repressor, Oct-2, irrespective of the presence or absence of morphine.	Nitrogen	25-26	tyrosine hydroxylase	Homo sapiens	60-62
12206675-1	2002	Cytochrome P450 (P450) 2D6 was first identified as the polymorphic human debrisoquine hydroxylase and subsequently shown to catalyze the oxidation of a variety of drugs containing a basic nitrogen.	Nitrogen	188-196	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-26
12236755-5	2002	Under standard thermodynamic conditions (STP), C-H addition via the D pathway has DeltaG(o)(+ +) = 36.3 kcal/mol for CyH (35.1 kcal/mol for n-PrH).	Nitrogen	1-2	chymase 1	Homo sapiens	117-120
12236755-7	2002	At conditions under which acceptorless dehydrogenation is thermodynamically possible (for example, T = 150 degrees C and P(H)2 = 1.0 x 10(-7) atm), DeltaG(+ +) for C-H addition to ((Me)PCP)Ir (plus a molecule of free H(2)) is very low (17.5 kcal/mol for CyH, 16.7 kcal/mol for n-PrH).	Nitrogen	5-6	chymase 1	Homo sapiens	254-257
12236755-9	2002	For CyH, the calculated DeltaG(o)(+ +) for C-H addition to ((Me)PCP)IrH(2) on the A pathway is 35.2 kcal/mol (32.7 kcal/mol for n-PrH).	Nitrogen	54-55	chymase 1	Homo sapiens	4-7
12236761-18	2002	In conclusion, the novel metal fragment fac-[M(N)(PXP)](2+) could be utilized as an efficient synthon for the preparation of a large class of asymmetrical, nitrido heterocomplexes incorporating a particular diphosphine ligand and a variety of bidentate chelating molecules.	Nitrogen	46-49	FA complementation group C	Homo sapiens	40-43
12418581-13	2002	In the N+ patients, the mean value of CD4+/CD8+ ratio was constant, although not significantly, lower than in controls; however it progressively increased from the first to the last subinterval.	Nitrogen	7-9	CD4 molecule	Homo sapiens	38-41
12167610-10	2002	In view of the wide distribution of UT-B in rat vasculature, elevated blood urea nitrogen may lead to endothelial L-Arg deficiency in vivo.	Nitrogen	81-89	solute carrier family 14 member 1 (Kidd blood group)	Rattus norvegicus	36-40
12375574-6	2002	Mineral nitrogen (N) in the topsoil of amended plots of 10, 30, and 90 Mg ha-1 increased by 5, 14, and 26 kg (NO3(-)-N + NH4(+)-N) ha-1, respectively, the first summer and by 2, 5, and 10 kg (NO3(-)-N + NH4(+)-N) ha-1, respectively, the second summer compared with controls.	Nitrogen	8-16	Rho GTPase activating protein 45	Homo sapiens	131-135
12322753-5	2002	Concentrations of imine nitrogens in the compost spectra suggest that covalent binding by the diamines 2,4DANT and 2,6DANT is a significant process in the transformation of TNT into bound residues.	Nitrogen	24-33	chromosome 16 open reading frame 82	Homo sapiens	173-176
12208867-3	2002	Both ABCG5 and ABCG8 underwent N-linked glycosylation.	Nitrogen	31-32	ATP binding cassette subfamily G member 5	Homo sapiens	5-10
12375574-6	2002	Mineral nitrogen (N) in the topsoil of amended plots of 10, 30, and 90 Mg ha-1 increased by 5, 14, and 26 kg (NO3(-)-N + NH4(+)-N) ha-1, respectively, the first summer and by 2, 5, and 10 kg (NO3(-)-N + NH4(+)-N) ha-1, respectively, the second summer compared with controls.	Nitrogen	8-16	Rho GTPase activating protein 45	Homo sapiens	131-135
12456992-10	2002	Hence, imidazoline compounds may protect beta cells against damage caused by IL-1beta-induced free oxygen and nitrogen radicals.	Nitrogen	110-118	interleukin 1 beta	Rattus norvegicus	77-85
12235182-1	2002	We determined the role of N-linked glycosylation of apolipoprotein B (apoB) in the assembly and secretion of lipoproteins using transfected rat hepatoma McA-RH7777 cells expressing human apoB-17, apoB-37, and apoB-50, three apoB variants with different ability to recruit neutral lipids.	Nitrogen	26-27	apolipoprotein B	Rattus norvegicus	52-68
12235182-1	2002	We determined the role of N-linked glycosylation of apolipoprotein B (apoB) in the assembly and secretion of lipoproteins using transfected rat hepatoma McA-RH7777 cells expressing human apoB-17, apoB-37, and apoB-50, three apoB variants with different ability to recruit neutral lipids.	Nitrogen	26-27	apolipoprotein B	Rattus norvegicus	70-74
12235182-3	2002	When selective N-to-Q substitution was introduced at one or more of the five N-linked glycosylation sites within apoB-37 (N(158), N(956), N(1341), N(1350), and N(1496)), secretion efficiency of apoB-37 from transiently transfected cells was variably affected.	Nitrogen	15-16	apolipoprotein B	Homo sapiens	113-117
12235182-4	2002	When all five N-linked glycosylation sites were mutated within apoB-37, the secretion efficiency and association with lipoproteins were decreased by &gt;50% as compared with wild-type apoB-37.	Nitrogen	14-15	apolipoprotein B	Homo sapiens	63-67
12235182-4	2002	When all five N-linked glycosylation sites were mutated within apoB-37, the secretion efficiency and association with lipoproteins were decreased by &gt;50% as compared with wild-type apoB-37.	Nitrogen	14-15	apolipoprotein B	Homo sapiens	184-188
12235182-5	2002	Similarly, mutant apoB-50 with all of its N-linked glycosylation sites mutagenized showed decreased secretion efficiency and decreased lipoprotein association in both d &lt; 1.02 and d &gt; 1.02 g/ml fractions.	Nitrogen	42-43	apolipoprotein B	Homo sapiens	18-22
12196156-1	2002	The pentahaem enzyme cytochrome c nitrite reductase catalyses the reduction of nitrite to ammonia, a key reaction in the biological nitrogen cycle.	Nitrogen	132-140	cytochrome c, somatic	Homo sapiens	21-33
12127534-2	2002	Phosphonate and phosphinate analogues of N-acylated gamma-glutamylglutamate were tested for the ability to inhibit glutamate carboxypeptidase II (GCP II).	Nitrogen	41-42	folate hydrolase 1	Homo sapiens	146-152
12121907-10	2002	Metabolism of 1263W94 to its primary metabolite, an N-dealkylated analog, appeared to be mediated via the isozyme CYP3A4 in humans.	Nitrogen	52-53	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	114-120
12184773-4	2002	The saturation of one azomethine group causes the products to assume a fac configuration and induces the formation of one asymmetric carbon and one asymmetric nitrogen center in the chelating system.	Nitrogen	159-167	FA complementation group C	Homo sapiens	71-74
12145150-6	2002	Insulin treatment reduced leucine nitrogen flux and transamination rates in subjects with type 2 diabetes.	Nitrogen	34-42	insulin	Homo sapiens	0-7
12201200-4	2002	Overall, the particulate phase (NH4+ + NO3-) dominated the atmospheric nitrogen budget (particulate and gas phase, NH4+ + NO3- + NH3 + HNO3) by more than 90% of the median total mixing ratio in winter, and by more than 60% in summer.	Nitrogen	71-79	NBL1, DAN family BMP antagonist	Homo sapiens	39-42
12201200-4	2002	Overall, the particulate phase (NH4+ + NO3-) dominated the atmospheric nitrogen budget (particulate and gas phase, NH4+ + NO3- + NH3 + HNO3) by more than 90% of the median total mixing ratio in winter, and by more than 60% in summer.	Nitrogen	71-79	NBL1, DAN family BMP antagonist	Homo sapiens	122-125
12214661-0	2002	Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase.	Nitrogen	43-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	55-70
12214661-0	2002	Electron supply and catalytic oxidation of nitrogen by cytochrome P450 and nitric oxide synthase.	Nitrogen	43-51	nitric oxide synthase 2	Homo sapiens	75-96
12214661-1	2002	Cytochrome P450 and nitric oxide synthase (NOS) oxidize nitrogen atoms, although the substrates and transformations are highly restricted for NOS.	Nitrogen	56-64	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-15
12214661-1	2002	Cytochrome P450 and nitric oxide synthase (NOS) oxidize nitrogen atoms, although the substrates and transformations are highly restricted for NOS.	Nitrogen	56-64	nitric oxide synthase 2	Homo sapiens	20-41
12153565-7	2002	The biglycan isoforms are N-glycosylated, which demonstrates that a lack in N-glycosylation is not the reason for a smaller core.	Nitrogen	26-27	biglycan	Homo sapiens	4-12
12153565-7	2002	The biglycan isoforms are N-glycosylated, which demonstrates that a lack in N-glycosylation is not the reason for a smaller core.	Nitrogen	76-77	biglycan	Homo sapiens	4-12
12212958-9	2002	The co-infusion of recombinant human insulin-like growth factor-1 and total parenteral nutrition has a significant net anabolic effect, as demonstrated by nitrogen retention and reduction in urine protein excretion observed in rats.	Nitrogen	155-163	insulin like growth factor 1	Homo sapiens	37-65
12165425-2	2002	Under nitrogen-rich conditions, the GATA family transcriptional activators, Gln3 and Gat1, form complexes with Ure2, and are localized to the cytoplasm, which decreases NCR-sensitive expression.	Nitrogen	6-14	glutathione peroxidase	Saccharomyces cerevisiae S288C	111-115
12147719-2	2002	(1) Nitrate reductase catalyses the key step in inorganic nitrogen assimilation, (2) aldehyde oxidase(s) have been shown to catalyse the last step in the biosynthesis of the phytohormone abscisic acid, (3) xanthine dehydrogenase is involved in purine catabolism and stress reactions, and (4) sulphite oxidase is probably involved in detoxifying excess sulphite.	Nitrogen	58-66	aldehyde oxidase 1	Homo sapiens	85-101
12109901-4	2002	N-Demethylation of trans-(+)-3alpha-piperidine-based ligands leads to improved activity at the SERT and NET and modest changes at the DAT.	Nitrogen	0-1	solute carrier family 6 member 4	Homo sapiens	95-99
12130708-4	2002	Furthermore, depletion of PKC by 12-O-tetradecanoylphorbol-13-acetate exposure (48 h, 1 microM) also prevented OFQ/N-mediated mu and ORL1 desensitization.	Nitrogen	115-116	protein kinase C alpha	Homo sapiens	26-29
12130708-5	2002	OFQ/N pretreatment resulted in translocation of PKC-alpha, G protein-coupled receptor kinase 2 (GRK2) and GRK3 from the cytosol to the membrane, and this translocation was also blocked by chelerythrine.	Nitrogen	4-5	protein kinase C alpha	Homo sapiens	48-57
12130708-5	2002	OFQ/N pretreatment resulted in translocation of PKC-alpha, G protein-coupled receptor kinase 2 (GRK2) and GRK3 from the cytosol to the membrane, and this translocation was also blocked by chelerythrine.	Nitrogen	4-5	G protein-coupled receptor kinase 2	Homo sapiens	59-94
12130708-5	2002	OFQ/N pretreatment resulted in translocation of PKC-alpha, G protein-coupled receptor kinase 2 (GRK2) and GRK3 from the cytosol to the membrane, and this translocation was also blocked by chelerythrine.	Nitrogen	4-5	G protein-coupled receptor kinase 2	Homo sapiens	96-100
12225802-5	2002	The predicted sequence of ovocleidin-116 contained two consensus N-glycosylation sites, only one of which (Asn62) was found to be fully modified.	Nitrogen	65-66	matrix extracellular phosphoglycoprotein	Gallus gallus	26-40
12111224-0	2002	Expression of the NH(+)(4)-transporter gene LEAMT1;2 is induced in tomato roots upon association with N(2)-fixing bacteria.	Nitrogen	102-106	ammonium transporter 1 member 2	Solanum lycopersicum	44-52
12137964-7	2002	However, gastric inhibitory polypeptide (GIP) 10(-9) M prestimulated SRIF secretion is significantly inhibited by N/OFQ 10(-8) M (-45+/-11%; p&lt;0.05 vs. GIP).	Nitrogen	114-115	gastric inhibitory polypeptide	Rattus norvegicus	41-44
12137964-7	2002	However, gastric inhibitory polypeptide (GIP) 10(-9) M prestimulated SRIF secretion is significantly inhibited by N/OFQ 10(-8) M (-45+/-11%; p&lt;0.05 vs. GIP).	Nitrogen	114-115	gastric inhibitory polypeptide	Rattus norvegicus	155-158
12137964-9	2002	At the higher concentration of N/OFQ 10(-6) M, the inhibition of prestimulated SRIF secretion (-58+/-6%; p&lt;0.05 vs. GIP) is not influenced by the NOP receptor antagonist at the concentration of 10(-6) M (-49+/-9%; ns vs. GIP and N/OFQ) and 10(-5) M (-69+/-10%; ns vs. GIP and N/OFQ), respectively.	Nitrogen	31-32	gastric inhibitory polypeptide	Rattus norvegicus	119-122
12137964-9	2002	At the higher concentration of N/OFQ 10(-6) M, the inhibition of prestimulated SRIF secretion (-58+/-6%; p&lt;0.05 vs. GIP) is not influenced by the NOP receptor antagonist at the concentration of 10(-6) M (-49+/-9%; ns vs. GIP and N/OFQ) and 10(-5) M (-69+/-10%; ns vs. GIP and N/OFQ), respectively.	Nitrogen	31-32	gastric inhibitory polypeptide	Rattus norvegicus	224-227
12137964-9	2002	At the higher concentration of N/OFQ 10(-6) M, the inhibition of prestimulated SRIF secretion (-58+/-6%; p&lt;0.05 vs. GIP) is not influenced by the NOP receptor antagonist at the concentration of 10(-6) M (-49+/-9%; ns vs. GIP and N/OFQ) and 10(-5) M (-69+/-10%; ns vs. GIP and N/OFQ), respectively.	Nitrogen	31-32	gastric inhibitory polypeptide	Rattus norvegicus	224-227
12137964-10	2002	On the other hand, infusion of naloxone 10(-6) M attenuates the inhibitory effect of N/OFQ 10(-6) M significantly (-21+/-6%; p&lt;0.05 vs. GIP and N/OFQ).Thus, N/OFQ is an inhibitor of gastric somatostatin secretion.	Nitrogen	85-86	gastric inhibitory polypeptide	Rattus norvegicus	139-142
12137964-10	2002	On the other hand, infusion of naloxone 10(-6) M attenuates the inhibitory effect of N/OFQ 10(-6) M significantly (-21+/-6%; p&lt;0.05 vs. GIP and N/OFQ).Thus, N/OFQ is an inhibitor of gastric somatostatin secretion.	Nitrogen	85-86	somatostatin	Rattus norvegicus	193-205
12354539-3	2002	In comparison with the control plasmid and the IL-4-encoding plasmid, the IFN-gamma-encoding plasmid promoted increased blood urea nitrogen values and reduced the survival rate, and these changes were accompanied by the development of anti-nuclear antibody.	Nitrogen	131-139	interferon gamma	Mus musculus	74-83
12070712-11	2002	GM-CSF/IL-2 therapy seems to induce an immune suppressive stage compared to GM-CSF alone affecting cytotoxic mononuclear cells and B cells, which might be mediated through the neopterin metabolic pathway or other inducible immune suppressive factors such as reactive oxygen and nitrogen intermediates.	Nitrogen	278-286	interleukin 2	Homo sapiens	7-11
12065445-0	2002	Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes.	Nitrogen	55-56	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	16-22
12065445-8	2002	Orphenadrine, a specific inhibitor to CYP2B6, and ketoconazole, a specific inhibitor to CYP3A4, inhibited the N-demethylation of ketamine in human liver microsomes.	Nitrogen	110-111	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	88-94
12086682-10	2002	These data support the hypothesis that n-LDL increases O(2)(*-), which scavenges *NO, and suggest that n-LDL uncouples eNOS activity by decreasing the association of hsp90 as an initial step in signaling eNOS to generate O(2)(*-).	Nitrogen	46-47	nitric oxide synthase 3	Homo sapiens	119-123
12086682-10	2002	These data support the hypothesis that n-LDL increases O(2)(*-), which scavenges *NO, and suggest that n-LDL uncouples eNOS activity by decreasing the association of hsp90 as an initial step in signaling eNOS to generate O(2)(*-).	Nitrogen	46-47	nitric oxide synthase 3	Homo sapiens	204-208
12180536-4	2002	Furafylline (CYP1A2) and sulfaphenazole (CYP2C9) inhibited the N-demethylation to a lesser extent while quinidine (CYP2D6) or troleandomycine (CYP3A4) had no effect.	Nitrogen	63-64	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	143-149
12111224-7	2002	This suggests that root-associated N(2)-fixing bacteria do excrete NH(+)(4) to levels that can be sensed by tomato roots and is in agreement with the induction of expression of LEAMT1;2 with as low as &gt; or = 1 microM external NH(+)(4).	Nitrogen	35-36	ammonium transporter 1 member 2	Solanum lycopersicum	177-185
12200543-3	2002	First, the scaffold of intestinal fatty acid binding protein (IFABP) was tailored by molecular modeling and site-directed mutagenesis to position a carboxylate group close to the pyridine nitrogen of the cofactor.	Nitrogen	188-196	fatty acid binding protein 2	Homo sapiens	23-60
12200543-3	2002	First, the scaffold of intestinal fatty acid binding protein (IFABP) was tailored by molecular modeling and site-directed mutagenesis to position a carboxylate group close to the pyridine nitrogen of the cofactor.	Nitrogen	188-196	fatty acid binding protein 2	Homo sapiens	62-67
12200543-5	2002	By N-methylation of the pyridoxamine, a cationic cofactor was created and tethered to Cys60 of IFABP-V60C/L38K and -V60C/E51K; this latter strategy had the effect of permanently installing a positive charge on the cofactor.	Nitrogen	3-4	fatty acid binding protein 2	Homo sapiens	95-100
12110377-11	2002	In conclusion, substitution of Ser(5) with Lys, and/or N-methylation of Leu(9), were the most effective changes to increase functional and binding potency of NKA(4-10) at the human colon NK(2) receptor.	Nitrogen	55-56	tachykinin precursor 1	Homo sapiens	158-161
12112232-4	2002	We demonstrate, using a Big1p-GFP fusion construct, that Big1p is an N-glycosylated integral membrane protein with a Type I topology that is located in the endoplasmic reticulum (ER).	Nitrogen	69-70	Big1p	Saccharomyces cerevisiae S288C	24-29
12112232-4	2002	We demonstrate, using a Big1p-GFP fusion construct, that Big1p is an N-glycosylated integral membrane protein with a Type I topology that is located in the endoplasmic reticulum (ER).	Nitrogen	69-70	Big1p	Saccharomyces cerevisiae S288C	57-62
12050356-8	2002	In addition, although HERV-W Env mediates only slight syncytium formation or infection of mouse cells, it utilizes the mouse transporters mASCT1 and mASCT2 when their sites for N-linked glycosylation are eliminated by mutagenesis.	Nitrogen	177-178	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4	Mus musculus	138-144
12050356-8	2002	In addition, although HERV-W Env mediates only slight syncytium formation or infection of mouse cells, it utilizes the mouse transporters mASCT1 and mASCT2 when their sites for N-linked glycosylation are eliminated by mutagenesis.	Nitrogen	177-178	solute carrier family 1 (neutral amino acid transporter), member 5	Mus musculus	149-155
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	amino acid permease GAP1	Saccharomyces cerevisiae S288C	98-102
12036943-4	2002	To test this hypothesis, the effect of exogenous mutant p53 protein expression on genomic instability in human p53-/- Saos-2 cells was measured by the frequency of formation of N-(phosphoacetyl)-L-aspartate (PALA)-resistant (PALA(R)) colonies, mediated by gene amplification.	Nitrogen	177-178	tumor protein p53	Homo sapiens	56-59
12049793-8	2002	In conclusion, GOGAT expression promoted by reduction of juvenile hormone titer is quite important for enhanced utilization of nitrogen for synthesis of silk protein during the last larval instar.	Nitrogen	127-135	glutamate synthase	Bombyx mori	15-20
12039735-2	2002	We identified a sequence from A. nidulans similar to the glutathione S-transferase-like nitrogen regulatory domain of Saccharomyces cerevisiae Ure2.	Nitrogen	88-96	glutathione peroxidase	Saccharomyces cerevisiae S288C	143-147
12019204-2	2002	The present study was designed to establish the role of plasma urea nitrogen and L-arginine on hepatic CYP2E1 expression in rats or rats with acute renal failure.	Nitrogen	68-76	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	103-109
12007677-6	2002	Apparently, the probable induction of CYP3A4 by carbamazepine results in a nonstereoselective increase in N-demethylation of citalopram.	Nitrogen	106-107	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	38-44
12201212-0	2002	Implication of maternal nitrogen balance in the regulation of circulating levels of insulin-like growth factor-I in human pregnancy.	Nitrogen	24-32	insulin like growth factor 1	Homo sapiens	84-112
12201212-3	2002	In the present study, we investigated the effects of changes in nitrogen balance on serum IGF-I levels in normal and malnourished pregnant women (defined as having negative nitrogen balance).	Nitrogen	64-72	insulin like growth factor 1	Homo sapiens	90-95
12201212-13	2002	On the other hand, the changes in serum IGF-I levels in the 9 malnourished pregnant women were significantly correlated with those in nitrogen balance (y = 1.72x + 17.5; r = 0.60; P &lt; 0.05: linear regression analysis).	Nitrogen	134-142	insulin like growth factor 1	Homo sapiens	40-45
12062797-7	2002	A second focus of the review is the nitrogen regulation of the general amino acid permease, Gap1p, and the proline permease, Put4p, by ubiquitin mediated intracellular protein sorting in the secretory and endosomal pathways.	Nitrogen	36-44	amino acid permease GAP1	Saccharomyces cerevisiae S288C	92-97
12050247-8	2002	The slightly positive correlation between adiponectin and age, blood urea nitrogen, or creatinine levels was also observed (all P &lt; 0.001).	Nitrogen	74-82	adiponectin, C1Q and collagen domain containing	Homo sapiens	42-53
12545749-0	2002	[Variations and transformations of nitrogen pollutants in source and tap water of D-lake].	Nitrogen	35-43	SEC14 like lipid binding 2	Homo sapiens	69-72
12545749-6	2002	The simulate test shows that NH4+(-)N could change into NO2-(-)N, while No2-(-)N into NO3-(-)N, which is partly transformed into nitrogen gas by microorganism and majority of which are remained in tap water by form of NO3-(-)N.	Nitrogen	129-137	NBL1, DAN family BMP antagonist	Homo sapiens	86-89
12545749-6	2002	The simulate test shows that NH4+(-)N could change into NO2-(-)N, while No2-(-)N into NO3-(-)N, which is partly transformed into nitrogen gas by microorganism and majority of which are remained in tap water by form of NO3-(-)N.	Nitrogen	129-137	SEC14 like lipid binding 2	Homo sapiens	197-200
12545749-6	2002	The simulate test shows that NH4+(-)N could change into NO2-(-)N, while No2-(-)N into NO3-(-)N, which is partly transformed into nitrogen gas by microorganism and majority of which are remained in tap water by form of NO3-(-)N.	Nitrogen	129-137	NBL1, DAN family BMP antagonist	Homo sapiens	218-221
12009910-7	2002	The tetracopper clusters bound by Ace1 and Mac1 differ in that the Ace1 cluster is coordinated entirely by cysteinyl thiolate, whereas the cysteine-deficient Mac1 cluster appears to consist of a Cu(4)(S-Cys)(5)(N-His) cluster with a bridging histidyl-derived nitrogen.	Nitrogen	259-267	Mac1p	Saccharomyces cerevisiae S288C	43-47
12009910-7	2002	The tetracopper clusters bound by Ace1 and Mac1 differ in that the Ace1 cluster is coordinated entirely by cysteinyl thiolate, whereas the cysteine-deficient Mac1 cluster appears to consist of a Cu(4)(S-Cys)(5)(N-His) cluster with a bridging histidyl-derived nitrogen.	Nitrogen	259-267	Mac1p	Saccharomyces cerevisiae S288C	158-162
12056570-5	2002	Electrospray low energy collisionally induced (CID) spectra of multiply-charged AspN digest peptides with sulfinamide cross-links contained characteristic fragmentations that corresponded to simple cleavage of the nitrogen-sulfur bond with charge retention on either of the fragment ions, allowing conformation of cross-linked peptides.	Nitrogen	214-222	asporin	Mus musculus	80-84
11985729-5	2002	RESULTS: The mean (+/-SD) plasma VEGF level in NT patients (160.8 +/- 177.4 pg/mL) was fivefold higher than that in other patient groups (T, 17.7 +/- 4.9 pg/mL; B, 28.3 +/- 17.6 pg/mL) and the N group (14.9 +/- 7.0 pg/mL; P &lt; 0.01).	Nitrogen	47-48	vascular endothelial growth factor A	Homo sapiens	33-37
12005489-6	2002	Alterations to molecular mechanics parameters that reproduced the trends in the [Co(III)N(n)O(6-n)] series also resulted in a significant overall improvement in the predictions of Co(III)-N bond lengths in a series of Co(III) hexaamines, with all being reproduced within 0.006 A.	Nitrogen	90-92	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	84-87
12005489-6	2002	Alterations to molecular mechanics parameters that reproduced the trends in the [Co(III)N(n)O(6-n)] series also resulted in a significant overall improvement in the predictions of Co(III)-N bond lengths in a series of Co(III) hexaamines, with all being reproduced within 0.006 A.	Nitrogen	90-92	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	183-186
12005489-6	2002	Alterations to molecular mechanics parameters that reproduced the trends in the [Co(III)N(n)O(6-n)] series also resulted in a significant overall improvement in the predictions of Co(III)-N bond lengths in a series of Co(III) hexaamines, with all being reproduced within 0.006 A.	Nitrogen	90-92	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	81-88
12005489-6	2002	Alterations to molecular mechanics parameters that reproduced the trends in the [Co(III)N(n)O(6-n)] series also resulted in a significant overall improvement in the predictions of Co(III)-N bond lengths in a series of Co(III) hexaamines, with all being reproduced within 0.006 A.	Nitrogen	88-89	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	84-87
12005489-6	2002	Alterations to molecular mechanics parameters that reproduced the trends in the [Co(III)N(n)O(6-n)] series also resulted in a significant overall improvement in the predictions of Co(III)-N bond lengths in a series of Co(III) hexaamines, with all being reproduced within 0.006 A.	Nitrogen	88-89	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	183-186
12096925-3	2002	We found that interferon-gamma (IFN-gamma) treatment increased the presence of high molecular weight forms of CD95 in these cells as judged by Western analysis, and treatment of protein extracts with Peptide: N -glycosidase F indicated that the majority of high molecular weight forms were due to N-linked glycosylation.	Nitrogen	34-35	interferon gamma	Homo sapiens	14-30
12038599-7	2002	The mean reduction in LDL-C was 0.09-0.13 mmol/L in N and 0.05-0.20 mmol/L in CAD, while that in HDL-C was 0.02-0.06 mmol/L in N and 0.00-0.05 mmol/L in CAD.	Nitrogen	52-53	component of oligomeric golgi complex 2	Homo sapiens	22-27
12026081-6	2002	Ground water sample ages showed that maximum residence times were on the order of 50 to 70 yr. Reconstructed NO3- concentrations, estimated from measured NO3- and dissolved N gas showed that NO3- concentrations have been increasing in the aquifer since the 1940s, and have been above the 714 micromol L(-1) maximum contaminant level at most sites since the mid- to late-1960s.	Nitrogen	109-110	NBL1, DAN family BMP antagonist	Homo sapiens	154-157
12026081-6	2002	Ground water sample ages showed that maximum residence times were on the order of 50 to 70 yr. Reconstructed NO3- concentrations, estimated from measured NO3- and dissolved N gas showed that NO3- concentrations have been increasing in the aquifer since the 1940s, and have been above the 714 micromol L(-1) maximum contaminant level at most sites since the mid- to late-1960s.	Nitrogen	109-110	NBL1, DAN family BMP antagonist	Homo sapiens	154-157
12062418-1	2002	The membrane traffic and stability of the general amino acid permease Gap1 of Saccharomyces cerevisiae are under nitrogen control.	Nitrogen	113-121	amino acid permease GAP1	Saccharomyces cerevisiae S288C	70-74
12123058-1	2002	Pyridine and bis(TMS)ketene acetals (TMS = trimethylsilyl) react successively with methylchloroformate and iodine (or peracids) to give, via functionalized dihydropyridines, bicyclic nitrogen-containing lactones which have been characterized by X-ray crystallography.	Nitrogen	183-191	PYD and CARD domain containing	Homo sapiens	17-20
12123058-1	2002	Pyridine and bis(TMS)ketene acetals (TMS = trimethylsilyl) react successively with methylchloroformate and iodine (or peracids) to give, via functionalized dihydropyridines, bicyclic nitrogen-containing lactones which have been characterized by X-ray crystallography.	Nitrogen	183-191	PYD and CARD domain containing	Homo sapiens	37-40
11964163-0	2002	Overloading and removal of N-glycosylation targets on human acetylcholinesterase: effects on glycan composition and circulatory residence time.	Nitrogen	27-28	acetylcholinesterase (Cartwright blood group)	Homo sapiens	60-80
11933161-3	2002	The cDNA for SPP120 contains a complete open reading frame encoding 797 amino acid residues with 14 potential N-glycosylation sites.	Nitrogen	6-7	seminal plasma glycoprotein 120	Oreochromis niloticus	13-19
12007092-2	2002	Accurate single-crystal diffraction data were measured on a suitable crystal with Mo(K alpha) radiation at 125 K. The CoII ion is coordinated in a square bipyramidal fashion with four imino nitrogen atoms at the equatorial plane and two water molecules at the axial positions.	Nitrogen	190-198	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	118-122
12058909-4	2002	In both materials, TACN forms thermodynamically and kinetically stable Co(TACN)3+(2) complexes in which the six coordination sites of the Co(III) are occupied by nitrogens from the TACN.	Nitrogen	162-171	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	138-145
11959975-2	2002	The C-terminal domain of Ure2p controls nitrogen catabolism by complexing with the transcription factor, Gln3p, whereas the asparagine-rich N-terminal "prion" domain is responsible for amyloid filament formation (prion conversion).	Nitrogen	40-48	glutathione peroxidase	Saccharomyces cerevisiae S288C	25-30
11996888-2	2002	The presence of a nitrogen atom, charged at physiological pH, has frequently been considered to be a hallmark of P-gp substrates and inhibitors.	Nitrogen	18-26	ATP binding cassette subfamily B member 1	Homo sapiens	113-117
11937029-3	2002	Mutants lacking Bck1, a component of the MAP kinase branch of the pathway, fail to respond normally to nitrogen starvation, which causes entry into quiescence.	Nitrogen	103-111	mitogen-activated protein kinase kinase kinase BCK1	Saccharomyces cerevisiae S288C	16-20
11925166-7	2002	The rhenium-nitrogen bond length in the excited state is 0.08 A longer than in the ground electronic state, which is consistent with the difference in bond lengths of ReN bonds of bond order 3 and bond order 2.5 as determined from molecular structures.	Nitrogen	12-20	renin	Homo sapiens	167-170
11948665-5	2002	One-hour exposure to N+Glu- led to a transient inhibition ( approximately 50%) of NPY production manifesting within 24 hr and recovering by 5 days thereafter, a 2-hr exposure to N+Glu- led to a sustained inhibition (50-75%) manifesting 1-5 days thereafter, and a 4-hr exposure to N+Glu- led to a total irreversible suppression of BDNF-induced production of NPY manifesting within 24 hr and lasting 8 days after re-supply of oxygen and glucose.	Nitrogen	21-22	neuropeptide Y	Rattus norvegicus	82-85
11948665-5	2002	One-hour exposure to N+Glu- led to a transient inhibition ( approximately 50%) of NPY production manifesting within 24 hr and recovering by 5 days thereafter, a 2-hr exposure to N+Glu- led to a sustained inhibition (50-75%) manifesting 1-5 days thereafter, and a 4-hr exposure to N+Glu- led to a total irreversible suppression of BDNF-induced production of NPY manifesting within 24 hr and lasting 8 days after re-supply of oxygen and glucose.	Nitrogen	21-22	neuropeptide Y	Rattus norvegicus	357-360
11948665-5	2002	One-hour exposure to N+Glu- led to a transient inhibition ( approximately 50%) of NPY production manifesting within 24 hr and recovering by 5 days thereafter, a 2-hr exposure to N+Glu- led to a sustained inhibition (50-75%) manifesting 1-5 days thereafter, and a 4-hr exposure to N+Glu- led to a total irreversible suppression of BDNF-induced production of NPY manifesting within 24 hr and lasting 8 days after re-supply of oxygen and glucose.	Nitrogen	21-23	neuropeptide Y	Rattus norvegicus	82-85
11948665-5	2002	One-hour exposure to N+Glu- led to a transient inhibition ( approximately 50%) of NPY production manifesting within 24 hr and recovering by 5 days thereafter, a 2-hr exposure to N+Glu- led to a sustained inhibition (50-75%) manifesting 1-5 days thereafter, and a 4-hr exposure to N+Glu- led to a total irreversible suppression of BDNF-induced production of NPY manifesting within 24 hr and lasting 8 days after re-supply of oxygen and glucose.	Nitrogen	21-23	neuropeptide Y	Rattus norvegicus	357-360
11948665-6	2002	Moreover, 1-hr exposure to N+Glu- led to a substantial and 4-hr exposure led to a total disappearance of immunostaining for MAP-2 and NPY but not for GFAP; indicating that neurons are the primary cell-type damaged by oxygen-glucose deprivation.	Nitrogen	27-28	neuropeptide Y	Rattus norvegicus	134-137
11955010-3	2002	In most crystal structures of actin, the delta1-nitrogen of the methylated H73 forms a hydrogen bond with the carbonyl of G158.	Nitrogen	48-56	actin	Saccharomyces cerevisiae S288C	30-35
11912238-12	2002	Consequently, wild-type plants growing in unfavourable light regimes and antisense RBCS transformants are simultaneously carbon- and nitrogen-limited.	Nitrogen	133-141	ribulose bisphosphate carboxylase small chain S41, chloroplastic	Nicotiana tabacum	83-87
12058967-5	2002	Ultraviolet light, cisplatin, and nitrogen mustards produce damage that is repaired by a p53-regulated pathway.	Nitrogen	34-42	tumor protein p53	Homo sapiens	89-92
11983428-0	2002	Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation.	Nitrogen	146-147	stromal interaction molecule 1	Homo sapiens	0-30
11983428-0	2002	Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation.	Nitrogen	146-147	stromal interaction molecule 1	Homo sapiens	32-37
11983428-3	2002	We have defined the transmembrane topology of STIM1 by determining the sites of N-linked glycosylation.	Nitrogen	80-81	stromal interaction molecule 1	Homo sapiens	46-51
11983428-4	2002	We have confirmed that STIM1 is modified by N-linked glycosylation at two sites within the SAM domain itself, deduced as asparagine residues N131 and N171, demonstrating that STIM1 is translocated across the membrane of the endoplasmic reticulum such that the SAM domain resides within the endoplasmic reticulum (ER) lumen.	Nitrogen	44-45	stromal interaction molecule 1	Homo sapiens	23-28
11983428-4	2002	We have confirmed that STIM1 is modified by N-linked glycosylation at two sites within the SAM domain itself, deduced as asparagine residues N131 and N171, demonstrating that STIM1 is translocated across the membrane of the endoplasmic reticulum such that the SAM domain resides within the endoplasmic reticulum (ER) lumen.	Nitrogen	44-45	stromal interaction molecule 1	Homo sapiens	175-180
11914108-8	2002	In addition, 24 h urinary nitrogen excretion decreased by 26% (P&lt;0.01) after GH treatment, while skeletal muscle protein synthesis and 3-methylhistidine excretion in urine remained unchanged.	Nitrogen	26-34	growth hormone 1	Homo sapiens	80-82
11914108-11	2002	The nitrogen retention accompanying GH treatment seems to be due largely to improved nitrogen balance in non-muscle tissue.	Nitrogen	4-12	growth hormone 1	Homo sapiens	36-38
11914108-11	2002	The nitrogen retention accompanying GH treatment seems to be due largely to improved nitrogen balance in non-muscle tissue.	Nitrogen	85-93	growth hormone 1	Homo sapiens	36-38
11912240-0	2002	The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops.	Nitrogen	64-72	glutamate-ammonia ligase	Homo sapiens	12-32
11912240-0	2002	The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops.	Nitrogen	127-135	glutamate-ammonia ligase	Homo sapiens	12-32
11912240-1	2002	This short review outlines the central role of glutamine synthetase (GS) in plant nitrogen metabolism and discusses some possibilities for crop improvement.	Nitrogen	82-90	glutamate-ammonia ligase	Homo sapiens	47-67
11912240-12	2002	Results with transgenic plants containing transferred GS genes suggest that there may be ways in which it is possible to improve the efficiency with which crop plants use nitrogen.	Nitrogen	171-179	glutamate-ammonia ligase	Homo sapiens	54-56
11922745-2	2002	space reduced TNF-alpha and IL-1beta mRNA synthesis in the brain after laparotomy, resulting in a reduction of nitrogen excretion in the urine.	Nitrogen	111-119	tumor necrosis factor	Rattus norvegicus	14-23
11922745-2	2002	space reduced TNF-alpha and IL-1beta mRNA synthesis in the brain after laparotomy, resulting in a reduction of nitrogen excretion in the urine.	Nitrogen	111-119	interleukin 1 beta	Rattus norvegicus	28-36
11844988-6	2002	Administration of recombinant growth hormone has resulted in positive nitrogen balance, and studies in mechanically ventilated patients suggest that it may shorten the need for ventilatory support.	Nitrogen	70-78	growth hormone 1	Homo sapiens	30-44
12018439-0	2002	Use of milk urea nitrogen to improve dairy cow diets.	Nitrogen	17-25	Weaning weight-maternal milk	Bos taurus	7-11
12018439-1	2002	The hypothesis of this field study was that providing farmers with information regarding their herd"s milk urea nitrogen (MUN) would result in more accurate feed management and a change in MUN toward target values.	Nitrogen	112-120	Weaning weight-maternal milk	Bos taurus	102-106
11863451-11	2002	Removal of chylomicron-sized n-6 TG emulsions is modulated by lipoprotein lipase (LPL), apoE, LDL-R, and lactoferrin-sensitive pathways.	Nitrogen	21-22	apolipoprotein E	Mus musculus	88-92
12078013-1	2002	We analyzed nitrogen budgets at national and regional levels on a timeline from 1961-2030 using a model, IAP-N 1.0.	Nitrogen	12-20	alkaline phosphatase, intestinal	Homo sapiens	105-108
11998441-2	2002	Substitution on indol nitrogen with benzyl and p-fluorobenzyl group of indole-2 carboxamides 8, 10, 11 provides fairly active COX-2 enzyme inhibitors.	Nitrogen	22-30	prostaglandin-endoperoxide synthase 2	Homo sapiens	126-131
12039072-2	2002	In addition, a common genetic variant of SHBG exists with an extra site for N-glycosylation at residue 327.	Nitrogen	76-77	sex hormone binding globulin	Homo sapiens	41-45
12039072-8	2002	Media containing SHBG N-glycosylation mutants exerted the same effect, but mutants lacking the O-linked oligosaccharide at Thr(7) failed to do so.	Nitrogen	22-23	sex hormone binding globulin	Homo sapiens	17-21
11868814-7	2002	Removal of the N-linked glycans from PH-20 with N-glycosidase F shifted the molecular weight from 64 kd to approximately 54 kd, its deduced molecular weight based on sequence analysis, suggesting that most if not all, of the potential N-glycosylation sites are linked to oligosaccharides.	Nitrogen	15-16	sperm adhesion molecule 1	Homo sapiens	37-42
14614267-2	2002	The GP5 protein has been known to be a 24.5-26 kDa N-glycosylated envelope protein.	Nitrogen	51-52	glycoprotein V platelet	Homo sapiens	4-7
11935354-1	2002	The molecular modeling of Co(II)-bleomycin previously performed by us through NMR and molecular dynamics indicates that the most favorable structure for this complex is six-coordinate, with the secondary amine in beta-aminoalanine, the N5 and N1 nitrogens in the pyrimidine and imidazole rings, respectively, and the amide nitrogen in beta-hydroxyhistidine as equatorial ligands.	Nitrogen	246-255	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	26-32
11935354-1	2002	The molecular modeling of Co(II)-bleomycin previously performed by us through NMR and molecular dynamics indicates that the most favorable structure for this complex is six-coordinate, with the secondary amine in beta-aminoalanine, the N5 and N1 nitrogens in the pyrimidine and imidazole rings, respectively, and the amide nitrogen in beta-hydroxyhistidine as equatorial ligands.	Nitrogen	246-254	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	26-32
11935354-6	2002	The results of this investigation on Fe(II)- and Co(II)-bleomycin are most consistent with a six-coordinate structure with five endogenous N-donors and a solvent molecule or the carbamoyl group as the sixth ligand.	Nitrogen	139-140	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	49-55
11953458-3	2002	BACE maturation involves cysteine bridge formation, N -glycosylation and propeptide removal.	Nitrogen	52-53	beta-secretase 1	Homo sapiens	0-4
11924859-4	2002	At low nitrogen levels, the removal rate increased with increasing N:C ratio for both NH3 and NO3.	Nitrogen	7-15	NBL1, DAN family BMP antagonist	Homo sapiens	94-97
11924859-4	2002	At low nitrogen levels, the removal rate increased with increasing N:C ratio for both NH3 and NO3.	Nitrogen	67-68	NBL1, DAN family BMP antagonist	Homo sapiens	94-97
11861825-7	2002	In addition, mutations of N-linked glycosylation sites in the V1/V2 region, previously shown to enhance antigenicity and immunogenicity, made the 239 Env partially CD4 independent.	Nitrogen	26-27	endogenous retrovirus group W member 1, envelope	Homo sapiens	150-153
11861825-7	2002	In addition, mutations of N-linked glycosylation sites in the V1/V2 region, previously shown to enhance antigenicity and immunogenicity, made the 239 Env partially CD4 independent.	Nitrogen	26-27	CD4 molecule	Homo sapiens	164-167
11902788-4	2002	NO3- and N2 were identified as nitrogen byproducts from RDX and HMX oxidation.	Nitrogen	31-39	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
11698412-0	2002	Cytochrome c oxidase subunit III: a molecular marker for N-(4-hydroxyphenyl)retinamise-induced oxidative stress in hepatoma cells.	Nitrogen	57-58	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	0-32
11866530-6	2002	The solution structure of the VEGF receptor-binding domain-v107 complex was determined using 3940 (1970 per VEGF monomer) internuclear distance and 476 (238 per VEGF monomer) dihedral angle restraints derived from NMR data obtained using samples containing either (13)C/(15)N-labeled protein plus excess unlabeled peptide or (13)C/(15)N-labeled peptide plus excess unlabeled protein.	Nitrogen	214-215	vascular endothelial growth factor A	Homo sapiens	30-34
11866530-6	2002	The solution structure of the VEGF receptor-binding domain-v107 complex was determined using 3940 (1970 per VEGF monomer) internuclear distance and 476 (238 per VEGF monomer) dihedral angle restraints derived from NMR data obtained using samples containing either (13)C/(15)N-labeled protein plus excess unlabeled peptide or (13)C/(15)N-labeled peptide plus excess unlabeled protein.	Nitrogen	274-275	vascular endothelial growth factor A	Homo sapiens	30-34
11860338-7	2002	It was also found that the presence of a nitrogen atom in the C10 substituent might play a role in the interaction of analogues with microtubules.	Nitrogen	41-49	homeobox C10	Homo sapiens	62-65
12099350-8	2002	Thus, increases in M(A) with tree height and decreasing nitrogen content not only resulted in a lower plant foliar area (LAR = F(L)/M(A)), but also led to lower physiological activity of unit foliar biomass.	Nitrogen	56-64	protein tyrosine phosphatase receptor type F	Homo sapiens	121-124
11882629-8	2002	ET-1 plasma concentration was also higher in Cap+HS (8.95 +/-.16), Cap+HS+ABT-627 (9.82 +/- 1.22) and Cap+HS+A-192621 (10.97 +/- 0.57) than in Cap+NS (3.06 +/- 0.73) (P&lt;0.05).	Nitrogen	147-149	endothelin 1	Rattus norvegicus	0-4
11809823-3	2002	ARL2 was found to lack covalent N-myristoylation, present on all other members of the ARF family, thereby preserving the N-terminal amphipathic alpha-helix as a potential mitochondrial import sequence.	Nitrogen	32-33	ADP-ribosylation factor-like 2	Mus musculus	0-4
11842416-6	2002	With respect to the coordination sites, each Co(II) ion of the binuclear dioxygenated complexes is bound to one oxygen atom and four nitrogen atoms: N(pi) and N(tau) of two Carnos molecules, the peptide, and the terminal amino nitrogen atoms.	Nitrogen	133-141	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	45-51
11842416-6	2002	With respect to the coordination sites, each Co(II) ion of the binuclear dioxygenated complexes is bound to one oxygen atom and four nitrogen atoms: N(pi) and N(tau) of two Carnos molecules, the peptide, and the terminal amino nitrogen atoms.	Nitrogen	227-235	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	45-51
12442789-1	2002	This paper assesses the distribution of ammonium (NH4+) and nitrate (NO3-) nitrogen deposition in native bushland soil adjacent to an open ventilated poultry farm.	Nitrogen	75-83	NBL1, DAN family BMP antagonist	Homo sapiens	69-72
16233204-4	2002	The maximum NO3-N removal rate was 0.46 kg-Nm(-3)d(-1) at an HRT of 0.75 h. Nitrogen removal efficiency of 99.5% at an HRT of 1 h was obtained with a C/N ratio 2.58, corresponding to 4.3 g of soluble starch per 1 g of NO3-N.	Nitrogen	76-84	NBL1, DAN family BMP antagonist	Homo sapiens	12-15
16233204-4	2002	The maximum NO3-N removal rate was 0.46 kg-Nm(-3)d(-1) at an HRT of 0.75 h. Nitrogen removal efficiency of 99.5% at an HRT of 1 h was obtained with a C/N ratio 2.58, corresponding to 4.3 g of soluble starch per 1 g of NO3-N.	Nitrogen	76-84	NBL1, DAN family BMP antagonist	Homo sapiens	218-221
16233204-4	2002	The maximum NO3-N removal rate was 0.46 kg-Nm(-3)d(-1) at an HRT of 0.75 h. Nitrogen removal efficiency of 99.5% at an HRT of 1 h was obtained with a C/N ratio 2.58, corresponding to 4.3 g of soluble starch per 1 g of NO3-N.	Nitrogen	12-13	NBL1, DAN family BMP antagonist	Homo sapiens	218-221
11802729-12	2002	Myeloperoxidase might also use this mechanism to form sulfur-nitrogen cross-links in other inflammatory conditions.	Nitrogen	61-69	myeloperoxidase	Homo sapiens	0-15
11833649-1	2002	A centrifugal concentrator was applied for the substitution of nitrogen blow-down micro-concentration in dioxin/PCB sample preparation.	Nitrogen	63-71	pyruvate carboxylase	Homo sapiens	112-115
12806045-9	2002	N deposition in throughfall under mature pine trees at Camp Paivika after 7 months of exposure was extremely high (87 and 92 kg ha-1 based on the two collector types) compared to Barton Flats (11 and 13 kg ha(-1)).	Nitrogen	0-1	Rho GTPase activating protein 45	Homo sapiens	128-132
12806045-10	2002	A large proportion of the N deposited in throughfall at Camp Paivika occurred as fog drip, demonstrating the importance of fog deposition as an input source of N at this site.	Nitrogen	26-27	zinc finger protein, FOG family member 1	Homo sapiens	81-84
12806045-10	2002	A large proportion of the N deposited in throughfall at Camp Paivika occurred as fog drip, demonstrating the importance of fog deposition as an input source of N at this site.	Nitrogen	26-27	zinc finger protein, FOG family member 1	Homo sapiens	123-126
11779189-5	2002	Fcalpha/muR was expressed in a heterologous system which showed that the receptor was approximately 58 kDa in weight and was only minimally N-glycosylated.	Nitrogen	140-141	Fc alpha and mu receptor	Homo sapiens	0-11
11754575-5	2002	The SAR of the functionality on the pyrrolidine nitrogen of the trans-lactam has been investigated, and this has led to the discovery of potent serine protease inhibitors that are highly selective for the viral enzyme over the mammalian enzymes elastase, thrombin, and acetylcholine esterase.	Nitrogen	48-56	coagulation factor II, thrombin	Homo sapiens	255-291
12638757-2	2002	NH4+ can be further oxidised to NO3- during nitrification and NO3- can be reduced to gaseous nitrogen compounds during denitrification.	Nitrogen	93-101	NBL1, DAN family BMP antagonist	Homo sapiens	32-35
12638757-2	2002	NH4+ can be further oxidised to NO3- during nitrification and NO3- can be reduced to gaseous nitrogen compounds during denitrification.	Nitrogen	93-101	NBL1, DAN family BMP antagonist	Homo sapiens	62-65
12475556-4	2002	In the present study, we have demonstrated using both methods that the stimulation of BV-2 murine microglial cell line by gamma-interferon and lipopolysaccharide leads to the increase of intracellular oxygen concentration and no change in the intracellular nitrogen concentration.	Nitrogen	257-265	interferon gamma	Mus musculus	122-138
12382736-4	2002	The main dosimetric parameters of MCP-N dosemeters, such as thermally-induced fading, light sensitivity, minimum detectable dose, self-dose, zero-dose, energy response up to 6-7 MeV, influence of annealing and readout conditions on detector stability, have been tested.	Nitrogen	38-39	CD46 molecule	Homo sapiens	34-37
11786091-19	2002	The responses of OLETF MCs to n-LDL/ox-LDL and Ang II differed depending on the stage of diabetes.	Nitrogen	9-10	angiotensinogen	Rattus norvegicus	47-53
21669645-11	2001	We propose that this new malate dehydrogenase facilitates rapid nitrogen assimilation both in soybean root nodules and in developing soybean seeds, which are rich in protein.	Nitrogen	64-72	malate dehydrogenase	Glycine max	25-45
11595744-8	2001	This difference in TBP binding could imply differential recruitment of target proteins by ER alpha-N and ER beta-N.	Nitrogen	99-100	estrogen receptor 1	Homo sapiens	90-98
11733115-6	2001	Recently, it was found that PHA producing bacteria are able to grow simultaneously limited by carbon and nitrogen substrates.	Nitrogen	105-113	lamin B receptor	Homo sapiens	28-31
11733364-7	2001	Treatment with rabbit neutralizing antibodies to both KC and MIP-2 inhibited neutrophil infiltration into ischemic kidneys during reperfusion, restored renal function as assessed by decreased serum creatinine and urea nitrogen levels to near normal levels, and resulted in complete survival of treated animals.	Nitrogen	218-226	chemokine (C-X-C motif) ligand 2	Mus musculus	61-66
11811525-9	2001	These results suggested that the oxidation of NaN3 by the catalase/H2O2 system generates unknown peroxynitrite-like reactive nitrogen intermediates, which contribute to tyrosine nitration.	Nitrogen	125-133	catalase	Homo sapiens	58-66
11733564-4	2001	Serum transferrin was hypoglycosylated and patients" fibroblasts accumulated incomplete lipid-linked oligosaccharide precursors for N-linked protein glycosylation.	Nitrogen	132-133	transferrin	Homo sapiens	6-17
11705390-1	2001	The 1.9 A X-ray crystal structure of human myeloperoxidase complexed with cyanide (R = 0.175, R(free) = 0.215) indicates that cyanide binds to the heme iron with a bent Fe-C-N angle of approximately 157 degrees, and binding is accompanied by movement of the iron atom by 0.2 A into the porphyrin plane.	Nitrogen	174-175	myeloperoxidase	Homo sapiens	43-58
11720736-7	2001	Although several different exogenous carcinogens have been shown to selectively target p53, evidence supporting the endogenous insult of p53 from oxyradical and nitrogen-oxyradicals is accumulating.	Nitrogen	161-169	tumor protein p53	Homo sapiens	137-140
11746710-12	2001	The similar affinities of non-amines and conventional antidepressant drugs for the SERT support the view that an amine nitrogen is not essential for drugs to block serotonin transport with high affinity.	Nitrogen	119-127	solute carrier family 6 member 4	Homo sapiens	83-87
11500493-1	2001	Membrane trafficking of the general amino acid permease (Gap1) of Saccharomyces cerevisiae is under nitrogen regulation.	Nitrogen	100-108	amino acid permease GAP1	Saccharomyces cerevisiae S288C	57-61
11500493-2	2001	In cells growing on proline or urea as the sole nitrogen source, newly synthesized Gap1 is delivered to the plasma membrane, where it accumulates.	Nitrogen	48-56	amino acid permease GAP1	Saccharomyces cerevisiae S288C	83-87
11500493-3	2001	Upon addition of NH(4)(+), a preferential nitrogen source, Gap1 is endocytosed and targeted to the vacuole, where it is degraded.	Nitrogen	42-50	amino acid permease GAP1	Saccharomyces cerevisiae S288C	59-63
11711600-1	2001	The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation.	Nitrogen	143-144	cyclin dependent kinase inhibitor 2A	Homo sapiens	105-108
11711600-1	2001	The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation.	Nitrogen	143-144	cyclin dependent kinase inhibitor 2A	Homo sapiens	119-122
11711600-1	2001	The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation.	Nitrogen	143-144	cyclin dependent kinase inhibitor 2A	Homo sapiens	119-122
11711600-1	2001	The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation.	Nitrogen	322-323	cyclin dependent kinase inhibitor 2A	Homo sapiens	105-108
11711600-1	2001	The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation.	Nitrogen	322-323	cyclin dependent kinase inhibitor 2A	Homo sapiens	119-122
11711600-1	2001	The open reading frame III of Borna disease virus (BDV) codes for a protein with a mass of 16 kDa, named p16 or BDV-M. p16 was described as an N-glycosylated protein in several previous publications and therefore was termed gp18, although the amino acid sequence of p16 does not contain any regular consensus sequence for N glycosylation.	Nitrogen	322-323	cyclin dependent kinase inhibitor 2A	Homo sapiens	119-122
11711600-5	2001	Introduction of typical N-glycosylation sites at the proposed sites of p16 failed in carbohydrate attachment.	Nitrogen	24-25	cyclin dependent kinase inhibitor 2A	Homo sapiens	71-74
11714275-1	2001	Cytochrome P450 (P450) 2D6 oxidizes a wide variety of drugs typically at a distance of 5-7 A from a basic nitrogen on the substrate.	Nitrogen	106-114	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-26
11677137-3	2001	The molecular modeling study for CPA(2R,3R)-3 complex suggested that the lone pair electrons on the nitrogen of the aziridine ring in the inhibitor forms a coordinative bond with the active site zinc ion and the proton on the nitrogen is engaged in hydrogen bonding with one of the carboxylate oxygens of Glu-270.	Nitrogen	100-108	carboxypeptidase A1	Homo sapiens	33-36
11677137-3	2001	The molecular modeling study for CPA(2R,3R)-3 complex suggested that the lone pair electrons on the nitrogen of the aziridine ring in the inhibitor forms a coordinative bond with the active site zinc ion and the proton on the nitrogen is engaged in hydrogen bonding with one of the carboxylate oxygens of Glu-270.	Nitrogen	226-234	carboxypeptidase A1	Homo sapiens	33-36
11078958-5	2001	A deglycosylation study showed that excreted napsin A is N-glycosylated on apparently all of the three potential glycosylation sites.	Nitrogen	57-58	napsin A aspartic peptidase	Homo sapiens	45-53
11698453-5	2001	Computational analysis of the CDw92 protein sequence indicates 10 transmembrane domains, three potential N-linked glycosylation sites, and an amino acid stretch in the C-terminal region that is related to the immunoreceptor tyrosine-based inhibitory motif.	Nitrogen	105-106	solute carrier family 44 member 1	Homo sapiens	30-35
11710544-0	2001	Differential activities of decapeptide agonists of human C5a: the conformational effects of backbone N-methylation.	Nitrogen	101-102	complement C5a receptor 1	Homo sapiens	57-60
11695904-1	2001	The [URE3] phenotype in yeast Saccharomyces cerevisiae is due to an altered prion form of Ure2p, a protein involved in nitrogen catabolism.	Nitrogen	119-127	glutathione peroxidase	Saccharomyces cerevisiae S288C	90-95
11602510-0	2001	Characterization of dextromethorphan O- and N-demethylation catalyzed by highly purified recombinant human CYP2D6.	Nitrogen	44-45	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	107-113
11798245-3	2001	The progress of the disease (the development of glomerulonephritis, formation of glomerular IgG and C3 deposits, increase in the blood urea nitrogen values, and mortality) was parallel with an increase in serum IFN-gamma in uninfected NZBxNZWF(1)mice.	Nitrogen	140-148	interferon gamma	Mus musculus	211-220
11484179-7	2001	The statistical analysis showed the n-Bone % of TGF-beta1/OCP was significantly higher than that of the Control/OCP in week 4, whereas the r-Imp % of TGF-beta1/OCP was significantly lower than that of the Control/OCP.	Nitrogen	17-18	transforming growth factor, beta 1	Rattus norvegicus	48-57
11509577-2	2001	Cytochrome P450 (P450) 2D6 was first identified as the polymorphic human debrisoquine hydroxylase and subsequently shown to catalyze the oxidation of a variety of drugs containing a basic nitrogen.	Nitrogen	188-196	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-26
11714858-3	2001	Subsequent studies indicate that this product appears to result from N-chlorination of the N-terminal amino group of apoB-100 and dehydrohalogenation to the corresponding imine, which may form the hydrazone derivative directly, or after hydrolysis to the ketone.	Nitrogen	69-70	apolipoprotein B	Homo sapiens	117-125
11676606-0	2001	Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells.	Nitrogen	41-42	CD40 ligand	Homo sapiens	61-66
11676606-4	2001	Human CD154 contains a single N-linked glycosylation site at asparagine 240.	Nitrogen	30-31	CD40 ligand	Homo sapiens	6-11
11746604-1	2001	Deletion of the general amino acid permease gene GAP1 abolishes uptake of L-citrulline in Saccharomyces cerevisiae, resulting in the inability to grow on L-citrulline as sole nitrogen source.	Nitrogen	175-183	amino acid permease GAP1	Saccharomyces cerevisiae S288C	49-53
11698101-4	2001	Electrostatic interactions of the nitroimine group and bridgehead nitrogen in imidacloprid with particular nAChR amino acid residues are likely to have key roles in determining the selective toxicity of imidacloprid.	Nitrogen	66-74	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	107-112
11592999-9	2001	This structure clearly revealed that one of the aromatic rings of the inhibitor was covalently linked to the receptor through the main-chain nitrogen of Ala-62, a residue that has already been implicated in the binding of TNF-alpha to the TNFRc1.	Nitrogen	141-149	tumor necrosis factor	Homo sapiens	222-231
11576779-8	2001	The beta-ligand modulation efficiency could also be correlated to Pgp structural recognition elements such as hydrogen bonding potential, the presence of a basic nitrogen and planar aromatic ring.	Nitrogen	162-170	ATP binding cassette subfamily B member 1	Homo sapiens	66-69
11580295-1	2001	The oligosaccharyltransferase (OST) preferentially utilizes the fully assembled dolichol-linked oligosaccharide Glc(3)Man(9)GlcNAc(2)-PP-Dol as the donor for N-linked glycosylation of asparagine residues in N-X-T/S consensus sites in newly synthesized proteins.	Nitrogen	127-128	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	4-29
11580295-1	2001	The oligosaccharyltransferase (OST) preferentially utilizes the fully assembled dolichol-linked oligosaccharide Glc(3)Man(9)GlcNAc(2)-PP-Dol as the donor for N-linked glycosylation of asparagine residues in N-X-T/S consensus sites in newly synthesized proteins.	Nitrogen	127-128	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	31-34
11606318-11	2001	Blocking COX-2 pathway with NS 398 (15 - 30 microM) did not alter the cardiopulmonary resting variables.	Nitrogen	28-30	prostaglandin G/H synthase 2	Cavia porcellus	9-14
12240333-1	2001	A new N,O-bidentate pro-ligand (HL), [ML2] (M = Cu, Zn) and [CuL2][BF4] have been synthesised; [CuL2].4DMF and [CuL2][BF4].2CH2Cl2 have been crystallographically and spectroscopically characterised; these data indicate that [CuL2]+ cations are constituted as [Cu2+(L.)(L-)]+ and involve the phenoxyl radical L..	Nitrogen	6-7	cullin 2	Homo sapiens	61-65
11822291-6	2001	The flow rate of Nitrogen was 27 ml.min-1.	Nitrogen	17-25	CD59 molecule (CD59 blood group)	Homo sapiens	36-41
11566360-1	2001	Inosine monophosphate dehydrogenase (IMPDH) catalyzes the rate-limiting step in de novo purine biosynthesis and is a postulated key enzyme in nitrogen assimilation in ureide-exporting nodules.	Nitrogen	142-150	inosine monophosphate dehydrogenase	Glycine max	0-35
11566360-1	2001	Inosine monophosphate dehydrogenase (IMPDH) catalyzes the rate-limiting step in de novo purine biosynthesis and is a postulated key enzyme in nitrogen assimilation in ureide-exporting nodules.	Nitrogen	142-150	inosine monophosphate dehydrogenase	Glycine max	37-42
12240333-1	2001	A new N,O-bidentate pro-ligand (HL), [ML2] (M = Cu, Zn) and [CuL2][BF4] have been synthesised; [CuL2].4DMF and [CuL2][BF4].2CH2Cl2 have been crystallographically and spectroscopically characterised; these data indicate that [CuL2]+ cations are constituted as [Cu2+(L.)(L-)]+ and involve the phenoxyl radical L..	Nitrogen	6-7	cullin 2	Homo sapiens	96-100
12240333-1	2001	A new N,O-bidentate pro-ligand (HL), [ML2] (M = Cu, Zn) and [CuL2][BF4] have been synthesised; [CuL2].4DMF and [CuL2][BF4].2CH2Cl2 have been crystallographically and spectroscopically characterised; these data indicate that [CuL2]+ cations are constituted as [Cu2+(L.)(L-)]+ and involve the phenoxyl radical L..	Nitrogen	6-7	cullin 2	Homo sapiens	96-100
12240333-1	2001	A new N,O-bidentate pro-ligand (HL), [ML2] (M = Cu, Zn) and [CuL2][BF4] have been synthesised; [CuL2].4DMF and [CuL2][BF4].2CH2Cl2 have been crystallographically and spectroscopically characterised; these data indicate that [CuL2]+ cations are constituted as [Cu2+(L.)(L-)]+ and involve the phenoxyl radical L..	Nitrogen	6-7	cullin 2	Homo sapiens	96-100
11514339-8	2001	Further analysis revealed that ovarian STC had a much larger N-linked carbohydrate moiety (approximately 12 kDa) compared to CS STC (approximately 7 kDa), indicating that the two hormones were differentially posttranslationally modified.	Nitrogen	61-62	stanniocalcin	Oncorhynchus mykiss	39-42
11556812-1	2001	Cytochrome P450 (P450) 2D6 is a polymorphic human enzyme involved in the oxidation of &gt;50 drugs, most of which contain a basic nitrogen.	Nitrogen	130-138	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	0-26
11522683-10	2001	Increased cellular levels of the soluble N-ethylmaleimide attachment protein receptor (SNARE) proteins syntaxin 4 and vesicle-associated membrane protein (VAMP)-2 were also observed in the insulin-resistant SHRSP strain.	Nitrogen	41-42	insulin	Homo sapiens	189-196
11514404-6	2001	Significant associations were present between changes of serum intact osteocalcin and 24-h calcium excretion (P &lt;0.001), nitrogen balance and 24-h phosphorus excretion (P &lt;0.001), nitrogen balance and renal N-telopeptide excretion (P &lt;0.05), and between serum osteocalcin and nitrogen balance (P &lt;0.025).	Nitrogen	186-194	bone gamma-carboxyglutamate protein	Homo sapiens	70-81
11514404-6	2001	Significant associations were present between changes of serum intact osteocalcin and 24-h calcium excretion (P &lt;0.001), nitrogen balance and 24-h phosphorus excretion (P &lt;0.001), nitrogen balance and renal N-telopeptide excretion (P &lt;0.05), and between serum osteocalcin and nitrogen balance (P &lt;0.025).	Nitrogen	186-194	bone gamma-carboxyglutamate protein	Homo sapiens	70-81
11604023-3	2001	Data set 1 contains 176 compounds having one or more nitrogen atoms with some oxygen (log S[mol/L] range is -7.41 to 0.96).	Nitrogen	53-61	SET domain containing 1A, histone lysine methyltransferase	Homo sapiens	5-10
11553754-10	2001	These results collectively indicate that AtNrt2.1 and/or AtNrt2.2 genes play a key role in the regulation of the high-affinity NO(3)(-) uptake, and in the adaptative responses of the plant to both spatial and temporal changes in nitrogen availability in the environment.	Nitrogen	229-237	nitrate transporter 2:1	Arabidopsis thaliana	41-49
11439087-0	2001	Site-directed removal of N-glycosylation sites in BST-1/CD157: effects on molecular and functional heterogeneity.	Nitrogen	25-26	bone marrow stromal cell antigen 1	Homo sapiens	50-55
11520056-2	2001	In all eukaryotes, N-glycosylation utilizes the lipid-linked oligosaccharide (LLO) precursor, whose synthesis is initiated by the ALG7 gene.	Nitrogen	19-20	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	130-134
11520056-3	2001	To elucidate the key signaling and metabolic events affected by N-glycosylation, we performed genomewide expression profiling of yeast cells carrying a hypomorphic allele of ALG7.	Nitrogen	64-65	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	174-178
11675007-7	2001	The essential function of AUT8 for autophagy is further demonstrated by the lack of accumulation of autophagic vesicles in the vacuoles of aut8 Delta cells starved of nitrogen in the presence of the proteinase B inhibitor phenylmethylsulfonyl fluoride.	Nitrogen	167-175	Atg2p	Saccharomyces cerevisiae S288C	26-30
12049482-10	2001	Overall, our experiments reveal that nitrogenous substitutions at the permissive C-10 of the camptothecin backbone may lead to AchE inhibition, particularly if they involve a quaternary nitrogen.	Nitrogen	37-45	acetylcholinesterase (Cartwright blood group)	Homo sapiens	127-131
11487528-7	2001	Peroxynitrite, a highly reactive nitrogen molecule derived from the interaction of NO and superoxide anion, significantly increased COX-2 expression.	Nitrogen	33-41	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	132-137
11504269-8	2001	The rate of other metabolic routes mediated by CYP2D6 only corresponded to about one fifth of the CYP2D6 catalyzed N-demethylation rate.	Nitrogen	115-116	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	98-104
11483002-7	2001	Two secreted forms of neuroserpin were observed with molecular weights of approximately 49 and approximately 50 kDa which may represent alternative glycosylation at three putative N-linked glycosylation sites.	Nitrogen	180-181	Serpin 42Da	Drosophila melanogaster	22-33
11605980-0	2001	Protein-based inheritance in Saccharomyces cerevisiae: [URE3] as a prion form of the nitrogen regulatory protein Ure2.	Nitrogen	85-93	glutathione peroxidase	Saccharomyces cerevisiae S288C	113-117
11605980-1	2001	The [URE3] element of the yeast Saccharomyces cerevisiae results from the presence of an altered form of the nitrogen regulatory protein Ure2.	Nitrogen	109-117	glutathione peroxidase	Saccharomyces cerevisiae S288C	137-141
11769605-7	2001	The improvement in nitrogen retention may be associated with the increasing of ketone and insulin levels.	Nitrogen	19-27	insulin	Homo sapiens	90-97
11356843-9	2001	CAN1, DAL4, DAL5, MEP2, DAL1, DAL80, and GDH3 transcription is down-regulated by Vid30p function with proline as the nitrogen source.	Nitrogen	117-125	glutamate dehydrogenase (NADP(+)) GDH3	Saccharomyces cerevisiae S288C	41-45
11504269-1	2001	The authors assessed the in vitro contribution of cytochrome P450 (CYP) isoforms 1A2, 3A4, 2C9, 2C19, and 2D6 to the N-demethylation of clozapine mediated by human liver microsomal preparations (HLM).	Nitrogen	117-118	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	50-65
11504269-1	2001	The authors assessed the in vitro contribution of cytochrome P450 (CYP) isoforms 1A2, 3A4, 2C9, 2C19, and 2D6 to the N-demethylation of clozapine mediated by human liver microsomal preparations (HLM).	Nitrogen	117-118	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	67-70
11504269-8	2001	The rate of other metabolic routes mediated by CYP2D6 only corresponded to about one fifth of the CYP2D6 catalyzed N-demethylation rate.	Nitrogen	115-116	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	47-53
11519155-2	2001	Cytochrome P450(CYP) 2D6 is involved in the hydroxylation of TCAs, while N-demethylation of TCAs is mediated by other such as CYP2C19, 3A4 and 1A2.	Nitrogen	73-74	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	0-24
11439087-0	2001	Site-directed removal of N-glycosylation sites in BST-1/CD157: effects on molecular and functional heterogeneity.	Nitrogen	25-26	bone marrow stromal cell antigen 1	Homo sapiens	56-61
11439087-6	2001	BST-1 contains four putative N-glycosylation sites.	Nitrogen	29-30	bone marrow stromal cell antigen 1	Homo sapiens	0-5
11440974-3	2001	TNF-alpha caused a dose-dependent increase in reactive oxygen and nitrogen intermediates in CA SMCs (P&lt;0.05).	Nitrogen	66-74	tumor necrosis factor	Homo sapiens	0-9
11356835-5	2001	Repression of Gcn4p-regulated transcription by nitrogen starvation is independent of the ammonium sensing systems that include Mep2p and Gpa2p or Ure2p and Gln3p but depends on the four upstream open reading frames in the GCN4 mRNA leader sequence.	Nitrogen	47-55	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	137-142
11695720-2	2001	CYP3A4 seems to be the most important CYP isoform in both bioactivation and N-dechloroethylation of the alkylating prodrug ifosfamide, but informations about possible gender-related differences are lacking.	Nitrogen	76-77	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-6
11600233-2	2001	Pharmacomodulation at the phthalimidic nitrogen led to the selection of two pharmacophoric fragments (2,4-lutidinyl and beta-picolyl), allowing significant inhibition of TNFalpha production (compounds 12 and 17).	Nitrogen	39-47	tumor necrosis factor	Rattus norvegicus	170-178
11320094-0	2001	Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites.	Nitrogen	141-142	ATP binding cassette subfamily A member 4	Homo sapiens	58-62
11447862-4	2001	Calibration was performed by comparing data on nitrite plus nitrate as nitrogen (NO2 + NO3-N) concentrations in ground water to land-use, soils, and depth to first-encountered ground water data.	Nitrogen	71-79	NBL1, DAN family BMP antagonist	Homo sapiens	87-90
11454750-2	2001	A Saccharomyces kluyveri pyd3 mutant that is unable to grow on N-carbamyl-beta-alanine as the sole nitrogen source and exhibits diminished beta-alanine synthase activity was used to clone analogous genes from different eukaryotes.	Nitrogen	99-107	pyd3	Drosophila melanogaster	25-29
11454750-4	2001	When the S. kluyveri PYD3 gene was expressed in S. cerevisiae, which has no pyrimidine catabolic pathway, it enabled growth on N-carbamyl-beta-alanine as the sole nitrogen source.	Nitrogen	163-171	pyd3	Drosophila melanogaster	21-25
12702356-7	2001	A few genes, FSP2, RGS2, AQY1, YFL030W, were expressed more strongly with nitrogen limitation as compared to other conditions.	Nitrogen	74-82	GTPase-activating protein RGS2	Saccharomyces cerevisiae S288C	19-23
11443176-9	2001	In summary, continued GH substitution during fasting conserves nitrogen, which involves stimulation or maintenance of protein synthesis.	Nitrogen	63-71	growth hormone 1	Homo sapiens	22-24
11408558-2	2001	Metabolism of indinavir by CYP3A4 expressing Caco-2 cells grown on filters resulted in the formation of N-dealkylation products (M5 and M6) and hydroxylation of indinavir, which were preferentially secreted into the apical compartment.	Nitrogen	104-105	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	27-33
11320094-3	2001	To delineate between several proposed membrane topological models, we have identified the exocytoplasmic (extracellular/lumen) N-linked glycosylation sites on ABCR.	Nitrogen	127-128	ATP binding cassette subfamily A member 4	Homo sapiens	159-163
11402074-1	2001	The [URE3] prion (infectious protein) of yeast is a self-propagating, altered form of Ure2p that cannot carry out its normal function in nitrogen regulation.	Nitrogen	137-145	glutathione peroxidase	Saccharomyces cerevisiae S288C	86-91
11399197-8	2001	The interpretation of these data is in terms of this step (M, N = Mn or Co): M(OAc)(3) + N(II)Br(2) + HOAc --&gt; M(OAc)(2) + N(III)Br(2)OAc.	Nitrogen	62-63	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	128-131
11445959-6	2001	For n-PG, calibration graphs were linear over the range 1.0-300.0 mg L-1 in area and the RSD was between 1.4 and 1.5%.	Nitrogen	4-5	immunoglobulin kappa variable 1-16	Homo sapiens	69-72
11352817-2	2001	We hypothesized that this cytoskeletal damage is caused by upregulation of an inducible nitric oxide (NO) synthase (iNOS)-driven pathway that overproduces reactive nitrogen metabolites (RNMs) such as NO and peroxynitrite (OONO(-)), which cause actin nitration and disassembly.	Nitrogen	164-172	nitric oxide synthase 2	Homo sapiens	116-120
11404321-4	2001	However, Swe1 is essential for pseudohyphal differentiation under a number of nonstandard assay conditions including altered temperature and increased nitrogen.	Nitrogen	151-159	tyrosine protein kinase SWE1	Saccharomyces cerevisiae S288C	9-13
11353758-2	2001	We identified the CYP enzymes involved in the N-demethylation of ketamine enantiomers using pooled human liver microsomes and microsomes from human B-lymphoblastoid cells that expressed CYP enzymes.	Nitrogen	46-47	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	18-21
11353758-2	2001	We identified the CYP enzymes involved in the N-demethylation of ketamine enantiomers using pooled human liver microsomes and microsomes from human B-lymphoblastoid cells that expressed CYP enzymes.	Nitrogen	46-47	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	186-189
11353758-5	2001	Among the 12 cDNA-expressed CYP enzymes examined, CYP2B6, CYP2C9, and CYP3A4 showed high activities for the N-demethylation of both enantiomers at the substrate concentration of 1 mM.	Nitrogen	15-16	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	28-31
11353758-5	2001	Among the 12 cDNA-expressed CYP enzymes examined, CYP2B6, CYP2C9, and CYP3A4 showed high activities for the N-demethylation of both enantiomers at the substrate concentration of 1 mM.	Nitrogen	15-16	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	70-76
11353758-7	2001	Also, the intrinsic clearance (CL(int): V(max)/K(m)) of CYP2B6 for the N-demethylation of both enantiomers were 7 to 13 times higher than those of CYP2C9 and CYP3A4.	Nitrogen	71-72	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	158-164
11395611-1	2001	OBJECTIVES: To describe the sequential changes in the growth hormone (GH)/insulin-like growth factors axis and their relationship with nitrogen balance in children following cardiac surgery.	Nitrogen	135-143	growth hormone 1	Homo sapiens	54-68
11395611-1	2001	OBJECTIVES: To describe the sequential changes in the growth hormone (GH)/insulin-like growth factors axis and their relationship with nitrogen balance in children following cardiac surgery.	Nitrogen	135-143	insulin	Homo sapiens	74-81
11377048-2	2001	At pH &lt; or = 1, the only degradation compounds detected were phosphate ion (Pi) and chloroethylammonium chloride (CEA-HCl), resulting from the breakdown of the two P-N bonds (pathway Ia).	Nitrogen	169-170	CEA cell adhesion molecule 3	Homo sapiens	117-120
11432947-1	2001	To gain an insight into the diurnal changes of nitrogen assimilation in roots the in vitro activities of cytosolic and plasma membrane-bound nitrate reductase (EC 1.6.6.1), nitrite reductase (EC 1.7.7.1) and cytosolic and plastidic glutamine synthetase (EC 6.3.1.2) were studied.	Nitrogen	47-55	ferredoxin--nitrite reductase, chloroplastic-like	Nicotiana tabacum	173-190
11333905-5	2001	The N386K mutation resulted in loss of an N-linked glycosylation site, but additional mutagenesis showed that it was the presence of a lysine rather than loss of the glycosylation site that contributed to CD4 independence.	Nitrogen	4-5	CD4 molecule	Homo sapiens	205-208
11428664-2	2001	The CCl4 injection significantly increased the indicators of hepatic function (glutamate oxaloacetate transaminase, glutamate pyruvate transaminase), but not of renal function (blood urea nitrogen, glomerular filtration rate).	Nitrogen	188-196	C-C motif chemokine ligand 4	Rattus norvegicus	4-8
11346788-0	2001	Semiconducting non-molecular nitrogen up to 240 GPa and its low-pressure stability.	Nitrogen	29-37	glycophorin A (MNS blood group)	Homo sapiens	48-51
11352928-2	2001	Depending on nitrogen source, Gap1p is transported to the plasma membrane, where it functions for amino acid uptake, or to the vacuole, where it is degraded.	Nitrogen	13-21	amino acid permease GAP1	Saccharomyces cerevisiae S288C	30-35
11485170-5	2001	The nitrogen atom attached to the carbon cage formed a "[5,6]open" type aza substructure, which was confirmed by the appearance of 31-32 signals in the region of deltaC 133-148 (carbon shifts of Sp2 carbons of the cage) in the 13C nuclear magnetic resonance spectra.	Nitrogen	4-12	Sp2 transcription factor	Homo sapiens	195-198
11278492-4	2001	Mature Asp-2 has four N-glycosylation sites.	Nitrogen	22-23	beta-secretase 1	Homo sapiens	7-12
11346788-4	2001	Theory predicts that, in a pressure range between 50 and 94 GPa, diatomic nitrogen can be transformed into a non-molecular framework or polymeric structure with potential use as a high-energy-density material.	Nitrogen	74-82	glycophorin A (MNS blood group)	Homo sapiens	60-63
11346788-5	2001	Here we show that the non-molecular phase of nitrogen is semiconducting up to at least 240 GPa, at which pressure the energy gap has decreased to 0.4 eV.	Nitrogen	45-53	glycophorin A (MNS blood group)	Homo sapiens	91-94
11352866-2	2001	We examined the effects of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) genotypes on the levels of N-(2-hydroxyethyl)valine (HEV) adducts in the erythrocytes and sister chromatid exchange (SCE) in lymphocytes from a group of 58 operators of sterilizers that used EtO and nonexposed workers from nine hospitals in the United States and one hospital in Mexico City.	Nitrogen	106-107	glutathione S-transferase mu 1	Homo sapiens	72-77
11331002-2	2001	In mammalian cells, RAMP1 is required for mature N-glycosylation of the hCRLR predicted to occur at Asn(60), Asn(112), and/or Asn(117) in the amino-terminal extracellular domain.	Nitrogen	49-50	calcitonin receptor like receptor	Homo sapiens	72-77
11331002-4	2001	Moreover, the hCRLR and the Asn(117) mutants exhibited comparable N-glycosylation and cell surface expression, and the association with RAMP1 was only slightly impaired.	Nitrogen	66-67	calcitonin receptor like receptor	Homo sapiens	14-19
11331002-5	2001	In contrast, the hCRLR Asn(60,112) to Thr double mutant exhibited defective RAMP1-dependent N-glycosylation, and impaired cell surface expression and CGRP receptor function.	Nitrogen	92-93	calcitonin receptor like receptor	Homo sapiens	17-22
11380692-1	2001	Synthetic lipopeptides based on bacterial lipoprotein are efficient activators for monocytes/macrophages inducing the release of interleukin (IL)-1, IL-6, tumour necrosis factor-alpha (TNF-alpha), reactive oxygen/nitrogen intermediates, and the translocation of nuclear factor kappaB (NFkappaB).	Nitrogen	213-221	tumor necrosis factor	Mus musculus	185-194
11425798-1	2001	The N-glycosylation pattern of the neural cell adhesion molecule (NCAM), isolated from brains of newborn mice, has been analyzed.	Nitrogen	4-5	neural cell adhesion molecule 1	Mus musculus	35-64
11425798-1	2001	The N-glycosylation pattern of the neural cell adhesion molecule (NCAM), isolated from brains of newborn mice, has been analyzed.	Nitrogen	4-5	neural cell adhesion molecule 1	Mus musculus	66-70
11432923-1	2001	Nitrogen, which is a major limiting nutrient for plant growth, is assimilated as ammonium by the concerted action of glutamine synthetase (GS) and glutamate synthase (GOGAT).	Nitrogen	0-8	glutamine synthetase	Nicotiana tabacum	117-137
11344183-5	2001	Compared with the control group, 1,25-(OH)(2)D levels were significantly higher and 24,25-(OH)(2)D levels were lower in the PTH-N group and even more so in the PTH-H group.	Nitrogen	128-129	parathyroid hormone	Homo sapiens	124-127
11377691-1	2001	The greater lability of Co(II) relative to Co(III) can potentially be used to achieve selective delivery of nitrogen mustard type molecules to hypoxic cells.	Nitrogen	108-116	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	24-30
11377691-1	2001	The greater lability of Co(II) relative to Co(III) can potentially be used to achieve selective delivery of nitrogen mustard type molecules to hypoxic cells.	Nitrogen	108-116	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	43-50
11292354-5	2001	Two of the other hydrogen bonds between the inhibitor and active site of the trypsin and uPA complexes become short in the thrombin counterparts, extending the three-centered short hydrogen-bonding array into a tetrahedral array of atoms (three oxygen and one nitrogen) involved in short hydrogen bonds.	Nitrogen	260-268	plasminogen activator, urokinase	Homo sapiens	89-92
11401696-1	2001	In Saccharomyces cerevisiae, the ability to use proline as a nitrogen source requires the Put3p transcriptional regulator, which turns on the expression of the proline utilization genes, PUT1 and PUT2, in the presence of the inducer proline and in the absence of preferred nitrogen sources.	Nitrogen	61-69	proline dehydrogenase	Saccharomyces cerevisiae S288C	187-191
11401696-1	2001	In Saccharomyces cerevisiae, the ability to use proline as a nitrogen source requires the Put3p transcriptional regulator, which turns on the expression of the proline utilization genes, PUT1 and PUT2, in the presence of the inducer proline and in the absence of preferred nitrogen sources.	Nitrogen	273-281	proline dehydrogenase	Saccharomyces cerevisiae S288C	187-191
11267905-5	2001	Homologues of L-chain and P25 of D. spectabilis and P. xuthus show about 50% overall identity, respectively, with those of B. mori, but essential structural features; i.e. the three Cys residues in an L-chain and the eight Cys residues and one of the potential N-glycosylation sites in P25, are conserved in both species.	Nitrogen	261-262	fibrohexamerin	Bombyx mori	26-29
11331450-0	2001	Growth hormone together with glutamine-containing total parenteral nutrition maintains muscle glutamine levels and results in a less negative nitrogen balance after surgical trauma.	Nitrogen	142-150	growth hormone 1	Homo sapiens	0-14
11331450-1	2001	BACKGROUND: Muscle protein catabolism, reflected by a decrease in glutamine (GLN), a decrease in muscle protein synthesis, and a negative nitrogen balance can be reduced by either administration of GLN or growth hormone (GH).	Nitrogen	138-146	growth hormone 1	Homo sapiens	205-219
11278499-4	2001	By subcellular fractionation and immunoblot analysis, we detected an N-glycosylated band of approximately 34 kDa corresponding to AQP8 in hepatocyte plasma and intracellular microsomal membranes.	Nitrogen	69-70	aquaporin 8	Rattus norvegicus	130-134
11312913-1	2001	In the course of structural explorations around a series of potent CCK2 receptor antagonists, it was noted that simple N-methylation of the indolic N-H in the parent molecule gave rise to behavior in vivo that was consistent with the compound acting as an agonist.	Nitrogen	119-120	cholecystokinin B receptor	Homo sapiens	67-80
11292354-5	2001	Two of the other hydrogen bonds between the inhibitor and active site of the trypsin and uPA complexes become short in the thrombin counterparts, extending the three-centered short hydrogen-bonding array into a tetrahedral array of atoms (three oxygen and one nitrogen) involved in short hydrogen bonds.	Nitrogen	260-268	coagulation factor II, thrombin	Homo sapiens	123-131
11282084-9	2001	A 6 h oxygen deprivation with nitrogen resulted in elevated levels of Hsp60 (media: P=0.048), of Hsp72 (intima: P&lt;0.001 and media: P=0.004) and of Hsp73 (intima: P=0.029) in the saphenous vein.	Nitrogen	30-38	heat shock protein family A (Hsp70) member 1A	Homo sapiens	97-102
11152688-6	2001	BACE is palmitoylated at three Cys residues within its transmembrane/cytosolic tail and is sulfated at mature N-glycosylated moieties.	Nitrogen	110-111	beta-secretase 1	Homo sapiens	0-4
11414735-7	2001	There are six putative N-linked glycosylation sites in the MDL-1 long form.	Nitrogen	23-24	C-type lectin domain containing 5A	Homo sapiens	59-64
11457072-4	2001	Since EPR theory predicts an increase in Co(II) hyperfine splitting as donation from the axial N-donor ligand decreases, EPR spectroscopy could clarify the X-ray results.	Nitrogen	95-96	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	41-47
11795521-6	2001	Muscle glutamine synthetase mRNA increased 1.3- and 2.1-fold in young and old CR mice, suggesting increased disposal of nitrogen and carbon derived from protein catabolism for energy.	Nitrogen	120-128	glutamate-ammonia ligase (glutamine synthetase)	Mus musculus	7-27
11259570-8	2001	N-Demethylation of LAAM and nor-LAAM by expressed CYP3A4 was unusual, with hyperbolic velocity curves and Eadie-Hofstee plots and without evidence of positive cooperativity.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	50-56
11310677-3	2001	The mechanism of the nitrosation of enolate anion of acetone [CH3COCH2]- (1) with methyl nitrite CH3ONO (2) via an "open-chain" transition state without Na+ in the C-N bond formation process was studied by the ab initio MO method.	Nitrogen	101-102	cochlin	Homo sapiens	65-69
11298070-0	2001	Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil.	Nitrogen	62-63	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	22-37
11266435-4	2001	In response to nitrogen sources or amino acids, TOR regulates both transcription and translation, enabling cells to appropriately respond to growth-promoting signals.	Nitrogen	15-23	RAR related orphan receptor C	Homo sapiens	48-51
11328489-1	2001	N-methylated peptides as substrates for the oligopeptide transporter and P-glycoprotein in the intestinal mucosa.	Nitrogen	0-1	ATP binding cassette subfamily B member 1	Homo sapiens	73-87
11328489-8	2001	Interestingly, N-methylation of the Phe-Ala peptide bond of the terminally modified tripeptide Ac-Ala-Phe-Ala-NH2 decreased the substrate activity of the molecule for the efflux transporter P-gp.	Nitrogen	15-16	ATP binding cassette subfamily B member 1	Homo sapiens	190-194
11328489-9	2001	In contrast, N-methylation of the Ala-Phe peptide bond of the terminally modified tripeptide Ac-Ala-Phe-Ala-NH2 increased the substrate activity of the molecule for P-gp.	Nitrogen	13-14	ATP binding cassette subfamily B member 1	Homo sapiens	165-169
11389756-1	2001	Regulation of root N uptake by whole-plant signalling of N status was investigated at the molecular level in Arabidopsis thaliana plants through expression analysis of AtNrt2.1 and AtAmt1.1.	Nitrogen	19-20	nitrate transporter 2:1	Arabidopsis thaliana	168-176
11389756-1	2001	Regulation of root N uptake by whole-plant signalling of N status was investigated at the molecular level in Arabidopsis thaliana plants through expression analysis of AtNrt2.1 and AtAmt1.1.	Nitrogen	57-58	nitrate transporter 2:1	Arabidopsis thaliana	168-176
11267662-4	2001	These GmNRT1 genes and the GmNRT2 gene, encoding a soybean NRT2 nitrate transporter, showed different expression patterns to each other under various nitrogen conditions.	Nitrogen	150-158	NRT2 protein	Glycine max	27-33
11267662-4	2001	These GmNRT1 genes and the GmNRT2 gene, encoding a soybean NRT2 nitrate transporter, showed different expression patterns to each other under various nitrogen conditions.	Nitrogen	150-158	NRT2 protein	Glycine max	29-33
11267662-5	2001	Specifically, GmNRT1-3 was constitutively expressed in both roots and leaves, while GmNRT1-2 was gradually expressed as the roots developed in the presence of ammonium as a nitrogen source, but not in the presence of both ammonium and nitrate.	Nitrogen	173-181	NRT2 protein	Glycine max	84-92
29712162-1	2001	mu4 end-on coordination (through the N atom) of the pseudohalogeno ligands X- =N3- and NCO- has been observed in the isostructural nonanuclear CoII cages with the general formula [Co9 {(2-C5 H4 N)2 CO2 }4 (O2 CMe)8 X2 ]; this mode is imposed by the trapping of anions X- into cavities formed inside the cage.	Nitrogen	37-38	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	143-147
11298070-9	2001	Overall, 75% or more of the N-demethylation of sildenafil at any concentration is probably attributable to CYP3A4.	Nitrogen	28-29	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	107-113
11251288-6	2001	Here, we have shown that the approach can be applied to the glycoprotein hormone erythropoietin, an important therapeutic glycoprotein with three sites of N-glycosylation that are essential for in vivo biological activity.	Nitrogen	155-156	erythropoietin	Homo sapiens	81-95
11238772-2	2001	It is postulated that the branched-chain aminotransferase (BCAT) isoenzymes (mitochondrial BCATm and cytosolic BCATc) are localized in different cell types and operate in series to provide nitrogen for optimal rates of de novo glutamate synthesis.	Nitrogen	189-197	branched chain amino acid transaminase 2	Homo sapiens	91-96
11179447-7	2001	melanogaster SERT chimera studies implicated the first two SERT transmembrane domains (TMDs) in the potency of the indole nitrogen-substituted compounds N-isopropyltryptamine (NIT), 5-methoxy-N-isopropyltryptamine (5-MNIT), and the 7-substituted compound 7-benzyloxytryptamine (7BT).	Nitrogen	122-130	solute carrier family 6 member 4	Homo sapiens	59-63
11171045-11	2001	Thus the tunicamycin-mediated inhibition of N-linked glycosylation interferes with the production of apoB-100 that is mediated by both proteasomal and non-proteasomal pathways.	Nitrogen	44-45	apolipoprotein B	Homo sapiens	101-109
11231933-6	2001	RESULTS: Treatment with GLP-2 improved the intestinal absorption of energy 3.5% +/- 4.0% (mean +/- SD) from 49.9% to 53.4% (P = 0.04), wet weight 11% +/- 12% from 25% to 36% (P = 0.04), and nitrogen 4.7% +/- 5.4% from 47.4% to 52.1% (P = 0.04).	Nitrogen	190-198	glucagon	Homo sapiens	24-29
11228984-4	2001	A stoichiometric analysis, taking into account the amount of protons produced or consumed by each process involving nitrogen, revealed that monthly variations of NO3- and NH4+ with ammonification, nitrification and denitrification could explain the 28 and 62% alkalinity variations at all stations, except one.	Nitrogen	116-124	NBL1, DAN family BMP antagonist	Homo sapiens	162-165
11179215-2	2001	We have investigated the role of membrane topology in the N-glycosylation of PrP by expressing a C-terminal transmembrane anchored form, PrP-CTM, an N-terminal transmembrane anchored form, PrP-NTM, a double-anchored form, PrP-DA, and a truncated form, PrPDeltaGPI, in human neuroblastoma SH-SY5Y cells.	Nitrogen	58-59	prion protein	Homo sapiens	77-80
11179215-4	2001	In contrast, PrP-NTM, although membrane anchored and localized at the cell surface, was not N-glycosylated.	Nitrogen	17-18	prion protein	Homo sapiens	13-16
11179215-8	2001	These results indicate that C-terminal membrane anchorage is required for N-glycosylation of PrP.	Nitrogen	74-75	prion protein	Homo sapiens	93-96
11217864-0	2001	Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation.	Nitrogen	0-1	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	61-66
11217864-2	2001	Here we demonstrate that a deficiency in beta1,6 N-acetylglucosaminyltransferase V (Mgat5), an enzyme in the N-glycosylation pathway, lowers T-cell activation thresholds by directly enhancing TCR clustering.	Nitrogen	49-50	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	84-89
11163793-3	2001	This observation was not expected as earlier results had suggested that either positively charged residues or the presence of a nitrogen-containing residue at the external TEA(+) binding site (R487 in hKv1.5) caused current loss upon removal of [K(+)](o).	Nitrogen	128-136	potassium voltage-gated channel subfamily A member 5	Homo sapiens	201-207
11227268-5	2001	Furthermore, model results also suggest that a 50% increase in N deposition will cause a 15% increase in the streamwater NO3-N concentrations.	Nitrogen	63-64	NBL1, DAN family BMP antagonist	Homo sapiens	121-124
11680875-5	2001	CD59, for example, has over 100 different sugars at one N-linked glycosylation site.	Nitrogen	56-57	CD59 molecule (CD59 blood group)	Homo sapiens	0-4
11440179-2	2001	In this study chlorination of N-acTyr residue at positions 3 and 5 in reactions with NaOCl, chloramines and the myeloperoxidase (MPO)-H2O2-Cl- chlorinating system were invesigated.	Nitrogen	30-31	myeloperoxidase	Homo sapiens	112-127
11440179-2	2001	In this study chlorination of N-acTyr residue at positions 3 and 5 in reactions with NaOCl, chloramines and the myeloperoxidase (MPO)-H2O2-Cl- chlorinating system were invesigated.	Nitrogen	30-31	myeloperoxidase	Homo sapiens	129-132
11481030-2	2001	It has been suggested that both reactive oxygen and nitrogen metabolites participate in regulating adhesion molecule expression in response to TNF-alpha.	Nitrogen	52-60	tumor necrosis factor	Homo sapiens	143-152
11857273-6	2001	In the cytochrome c the enhancement of the bands assigned to the porphyrin macrocycle stretching mode allowed the supposition of the N-adsorption onto the colloidal surface.	Nitrogen	133-134	cytochrome c, somatic	Homo sapiens	7-19
11197334-12	2001	To investigate how cyclic permutation of the two nitrogen atoms of a pyrazole might affect ER binding affinity, we prepared a new pyrazole core isomer, namely a 1,3,4-triaryl-5-alkyl-pyrazole (2), to compare it with our original pyrazole (1).	Nitrogen	49-57	estrogen receptor 1	Homo sapiens	91-93
11147801-11	2001	In summary, we find that suppression of GH during fasting leads to a 50% increase in urea-nitrogen excretion, together with an increased net release and appearance rate of phenylalanine across the forearm.	Nitrogen	90-98	growth hormone 1	Homo sapiens	40-42
11785667-3	2001	Next to the CBA/N strain of mice, carrying a single amino acid substitution mutation in the Btk gene, which results in the X-linked immunodeficiency (xid) phenotype, additional mouse models have been developed to study the role of Btk in vivo.	Nitrogen	0-1	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	92-95
11237291-1	2001	Spatial variability in N uptake and utilisation by swards within uniformly managed field units could be responsible for a significant proportion of the NH3, N2O, NO3- and NOx (NO and NO2) "pollutants" generated by agriculture and released to the environment.	Nitrogen	23-24	NBL1, DAN family BMP antagonist	Homo sapiens	162-165
11127921-9	2000	CD34 reactivity was 100% N in the carcinomatous components.	Nitrogen	25-26	CD34 molecule	Homo sapiens	0-4
11204706-7	2001	The efficiency of N utilization improved in the low degradable starch treatment, which had lower N excretion (65%) and higher protein concentration in milk.	Nitrogen	18-19	Weaning weight-maternal milk	Bos taurus	151-155
11590720-2	2001	The results showed: (1) Applying relative excessive N fertilizer could result large quantities of NO3- residue and NO3- movement downward in soil profiles; amending phosphate fertilizer or organic manure with nitrogen fertilizer together could significantly improve the status of NO3- leaching downward due to the balanced uptake of nutrients by crops.	Nitrogen	52-53	NBL1, DAN family BMP antagonist	Homo sapiens	98-101
11590720-2	2001	The results showed: (1) Applying relative excessive N fertilizer could result large quantities of NO3- residue and NO3- movement downward in soil profiles; amending phosphate fertilizer or organic manure with nitrogen fertilizer together could significantly improve the status of NO3- leaching downward due to the balanced uptake of nutrients by crops.	Nitrogen	52-53	NBL1, DAN family BMP antagonist	Homo sapiens	115-118
11590720-2	2001	The results showed: (1) Applying relative excessive N fertilizer could result large quantities of NO3- residue and NO3- movement downward in soil profiles; amending phosphate fertilizer or organic manure with nitrogen fertilizer together could significantly improve the status of NO3- leaching downward due to the balanced uptake of nutrients by crops.	Nitrogen	52-53	NBL1, DAN family BMP antagonist	Homo sapiens	115-118
11592675-4	2001	Nitrogen ELNES is similar to that of Sr(NO3)2, so nitrogen is contained as a NO3 group.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
11592675-4	2001	Nitrogen ELNES is similar to that of Sr(NO3)2, so nitrogen is contained as a NO3 group.	Nitrogen	50-58	NBL1, DAN family BMP antagonist	Homo sapiens	40-43
11592675-4	2001	Nitrogen ELNES is similar to that of Sr(NO3)2, so nitrogen is contained as a NO3 group.	Nitrogen	50-58	NBL1, DAN family BMP antagonist	Homo sapiens	77-80
11785906-10	2001	In microsomes from induced animal liver, CYP2B and CYP3A may contribute to both N-demethylation and 4-hydroxylation of antipyrine.	Nitrogen	80-81	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	51-56
11162427-1	2000	The single tryptophan at position 121 of human interleukin-2 (IL-2) can form an NH-pi hydrogen bond with Phe 117 involving the indole nitrogen and the benzene aromatic ring.	Nitrogen	134-142	interleukin 2	Homo sapiens	47-60
11162427-1	2000	The single tryptophan at position 121 of human interleukin-2 (IL-2) can form an NH-pi hydrogen bond with Phe 117 involving the indole nitrogen and the benzene aromatic ring.	Nitrogen	134-142	interleukin 2	Homo sapiens	62-66
11119727-1	2000	The human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively.	Nitrogen	107-108	calcitonin receptor like receptor	Homo sapiens	10-48
11119727-1	2000	The human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively.	Nitrogen	107-108	calcitonin receptor like receptor	Homo sapiens	50-55
11119727-1	2000	The human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively.	Nitrogen	107-108	calcitonin related polypeptide alpha	Homo sapiens	211-234
11119727-1	2000	The human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively.	Nitrogen	107-108	calcitonin related polypeptide alpha	Homo sapiens	236-240
11119727-2	2000	Three putative N-glycosylation sites Asn(60), Asn(112) and Asn(117) are present in the amino-terminal extracellular domain of the hCRLR.	Nitrogen	15-16	calcitonin receptor like receptor	Homo sapiens	130-135
11151385-2	2000	While at least the first two steps in the reaction of the free ligand have been found to involve only the secondary nitrogen centers, in both the Cu(II) and Co(III) complexes alkylation occurs only at the primary (1,8) centers, the greater ease of achieving a higher degree of alkylation of the Cu(II) complex being attributed to the lower charge of this species causing a lesser reduction of the nucleophilicity of the uncoordinated primary nitrogen atoms.	Nitrogen	442-450	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	157-164
11134892-0	2001	Reactive oxygen and nitrogen metabolites modulate fibronectin-induced fibroblast migration in vitro.	Nitrogen	20-28	fibronectin 1	Homo sapiens	50-61
11215662-4	2001	Ground water flow and NO3- -N measurements indicated that NO3- -N discharged to the riparian zone preferentially flowed through the A and B horizons of depressional wetlands located in relic meander scars, with NO3- -N decreasing from &gt; 12 to &lt; 0.5 mg L(-1).	Nitrogen	22-23	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
11215662-4	2001	Ground water flow and NO3- -N measurements indicated that NO3- -N discharged to the riparian zone preferentially flowed through the A and B horizons of depressional wetlands located in relic meander scars, with NO3- -N decreasing from &gt; 12 to &lt; 0.5 mg L(-1).	Nitrogen	22-23	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
11236507-8	2001	In case of mixed infection a significant increase in the concentration of IFN-gamma was registered in the subgroup of patients with the acute form of NS+ (39.9 pg/ml).	Nitrogen	150-153	interferon gamma	Homo sapiens	74-83
11113053-8	2000	The iNOS/L-arginine pathway mediated the latter activity, inasmuch as it was inhibited by treatment with N:(G)-monomethyl-L-arginine.	Nitrogen	105-107	nitric oxide synthase 2, inducible	Mus musculus	4-8
11164588-8	2000	An alternative system for assimilation of nitrogen through glutamate dehydrogenase in roots is proposed, while higher levels of ammonium and glutamine may fullfil the needs of organic nitrogen in the leaves.	Nitrogen	42-50	glutamate dehydrogenase	Vitis vinifera	59-82
11096049-9	2000	The depression of the VEGF-A production induced by aberrantly glycosylated IgA was mediated by NO because it was completely reversed by the NOS inhibitor, N:omega-nitro-L-arginine methyl ester.	Nitrogen	95-96	vascular endothelial growth factor A	Homo sapiens	22-28
11096049-9	2000	The depression of the VEGF-A production induced by aberrantly glycosylated IgA was mediated by NO because it was completely reversed by the NOS inhibitor, N:omega-nitro-L-arginine methyl ester.	Nitrogen	95-96	CD79a molecule	Homo sapiens	75-78
11133809-1	2000	In human fibroblasts, N:-phosphoacetyl-L-aspartate (PALA) and gamma-radiation induce reversible and irreversible p53-mediated G(1) cell cycle arrest, respectively.	Nitrogen	22-23	tumor protein p53	Homo sapiens	113-116
11082192-8	2000	The physiological significance of the differential sensitivity of PYC1 and PYC2 genes with respect to the nitrogen source in the growth medium is also discussed.	Nitrogen	106-114	pyruvate carboxylase 2	Saccharomyces cerevisiae S288C	75-79
11095593-7	2000	Interestingly, due to the higher fluorescent yield of the N-alkyl metabolites compared with the metabolite of MAMC, O-dealkylation of N-methyl MAMC by CYP2D6 can be measured with a more than 3-fold higher sensitivity.	Nitrogen	58-59	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	151-157
11185553-7	2000	Blotting analysis with lectins specific for carbohydrate moieties and treatment with glycosidases demonstrated that rHRG is a highly N-glycosylated protein with diverse carbohydrate structures.	Nitrogen	133-134	histidine-rich glycoprotein	Rattus norvegicus	116-120
11102743-7	2000	To further demonstrate the usefulness of the HTS-assay, IC(50) values of a series of five N-substituted analogs of 3, 4-methylenedioxyamphetamine for CYP2D6 have been determined.	Nitrogen	90-91	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	150-156
11428337-6	2000	The ability to produce reactive nitrogen intermediates in response to T. gondii infection, as detected by elevated levels of nitrate and nitrite in sera, was normal in tumour necrosis factor receptor knockout mice but was completely lacking in interferon-gamma receptor knockout mice, indicating that reactive nitrogen intermediates are also not responsible for induction of parasite HSP70.	Nitrogen	32-40	heat shock protein 1B	Mus musculus	384-389
11110874-6	2000	In old mice, the time of passive avoidance was significantly higher in the NS + NT group than in the control group at d 1 and 7 (P: &lt; 0.05).	Nitrogen	75-77	deiodinase, iodothyronine, type I	Mus musculus	118-127
11099414-0	2000	Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis.	Nitrogen	18-19	BH3 interacting domain death agonist	Homo sapiens	38-41
11132861-5	2000	Milk fat percentage and milk urea nitrogen concentration decreased linearly with supplementation.	Nitrogen	34-42	Weaning weight-maternal milk	Bos taurus	24-28
11050162-7	2000	These results are consistent with the hypothesis that the generation of oxygen/nitrogen species and unsaturated aldehydes from iron and copper overload in hemochromatosis and WD causes mutations in the p53 tumor suppressor gene.	Nitrogen	79-87	tumor protein p53	Homo sapiens	202-205
11133003-6	2000	The present study indicates that CYP3A plays a major role in N-dealkylation of and oxidation back to bromperidol as well as haloperidol and suggests that modification of in vivo CYP3A activity by inhibition or induction may affect the pharmacokinetics and therapeutic effects of haloperidol and bromperidol.	Nitrogen	61-62	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	33-38
11133003-0	2000	CYP3A is responsible for N-dealkylation of haloperidol and bromperidol and oxidation of their reduced forms by human liver microsomes.	Nitrogen	25-26	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-5
11133003-6	2000	The present study indicates that CYP3A plays a major role in N-dealkylation of and oxidation back to bromperidol as well as haloperidol and suggests that modification of in vivo CYP3A activity by inhibition or induction may affect the pharmacokinetics and therapeutic effects of haloperidol and bromperidol.	Nitrogen	61-62	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	178-183
11205256-9	2000	Chemosensitizers that block P-gp drug extrusion are generally lipid-soluble at physiological pH, possess a basic nitrogen atom and at least two co-planar rings.	Nitrogen	113-121	ATP binding cassette subfamily B member 1	Homo sapiens	28-32
11151747-13	2000	N-demethylated metabolites, formed by CYP3A4, were not observed in any of the cell lines.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	38-44
11193413-7	2000	The N34A mutant RNase A, in which the only potential N-glycosylation site, Asn34, is mutated to alanine, was also glycosylated, implying that glycosylation is not N-linked but O-linked.	Nitrogen	4-5	ribonuclease pancreatic	Bos taurus	16-23
11104279-14	2000	The efficiency of N utilization for milk protein synthesis was greatest (P &lt; 0.09) with the 15% CP diets.	Nitrogen	18-19	casein beta	Bos taurus	36-48
11054648-1	2000	Insulin-like growth factor-I (IGF-I) has been demonstrated to exert a nitrogen sparing effect, both experimentally and in patients after abdominal surgery.	Nitrogen	70-78	insulin like growth factor 1	Homo sapiens	0-28
11079462-4	2000	In the present study we investigated N-linked sugar chains of apo B-100 from patients with coronary artery disease (CAD) who had moderate hypercholesterolemia (less than 400 mg/dL).	Nitrogen	37-38	apolipoprotein B	Homo sapiens	62-71
11054648-1	2000	Insulin-like growth factor-I (IGF-I) has been demonstrated to exert a nitrogen sparing effect, both experimentally and in patients after abdominal surgery.	Nitrogen	70-78	insulin like growth factor 1	Homo sapiens	30-35
11046064-7	2000	The expressed CCR2B was found to be N:-glycosylated, as N:-glycosidase F treatment of the receptor or growth of the cells in tunicamycin reduced the receptor size to the same level, from 50 to 45 kDa.	Nitrogen	36-37	C-C motif chemokine receptor 2	Homo sapiens	14-19
11034839-6	2000	The reaction product was determined to be syn-2-nitrosopropene by comparing the observed and calculated rotational constants, kappa (Ray"s asymmetry parameter) and r(s) coordinates of the nitrogen atom.	Nitrogen	188-196	synapsin II	Homo sapiens	42-47
11144264-13	2000	A possible role for GS-1 and GDH co-acting in the synthesis of glutamine for the transport of nitrogen is discussed.	Nitrogen	94-102	glutamate dehydrogenase	Zea mays	29-32
11040050-9	2000	High iNOS versus eNOS selectivity was found for 1400W, whereas several isothiourea derivatives and 1400W displayed moderate n- versus eNOS selectivity.	Nitrogen	41-42	nitric oxide synthase 2	Homo sapiens	5-9
11058767-2	2000	PGDS is an N-glycosylated monomeric protein with an M(r) of 20000-31000 depending on the size of the glycosyl moiety.	Nitrogen	11-12	prostaglandin D2 synthase	Homo sapiens	0-4
10924510-5	2000	Initial studies indicated that BACE undergoes N-linked glycosylation at three of four potential sites.	Nitrogen	46-47	beta-secretase 1	Homo sapiens	31-35
11233193-0	2000	A Co(III) complex in a mixed sulfur/nitrogen ligand environment: modeling the substrate- and product-bound forms of the metalloenzyme thiocyanate hydrolase.	Nitrogen	36-44	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	2-9
10966936-6	2000	Liver L-tryptophan 2,3-dioxygenase activity (TDO), a rate-limiting enzyme of the kynurenine pathway, was increased in proportion to blood urea nitrogen and creatinine levels.	Nitrogen	143-151	tryptophan 2,3-dioxygenase	Rattus norvegicus	45-48
11015193-15	2000	Subcellular fractionation experiments showed that both the N-myristoyl group and Ca(2+)-binding contribute to the ability of Frq1 to associate with membranes.	Nitrogen	59-60	frequenin	Saccharomyces cerevisiae S288C	125-129
11030712-2	2000	We determined the effects of N-[(1S,trans)-2-hydroxycyclopentyl]adenosine (GR79236), a selective agonist of the G(i)PCR adenosine A(1) receptor, on sarcolemmal NHE activity in adult rat ventricular myocytes (n=8-10 per group).	Nitrogen	29-30	adenosine A1 receptor	Rattus norvegicus	120-143
10953083-2	2000	A GAP1 strain can utilize L-citrulline as the sole nitrogen source but cannot grow in the presence of the toxic amino acid D-histidine.	Nitrogen	51-59	amino acid permease GAP1	Saccharomyces cerevisiae S288C	2-6
11011097-3	2000	The deduced polypeptide of CABGLU which contains a C-terminal extension N-glycosylated at a single site characterized as typical structure of class I beta-1,3-glucanase has a high level of identity with tobacco basic beta-1,3-glucanase (77.4%), but only a moderate level of identity with tomato acidic beta-1,3-glucanase (42.6%).	Nitrogen	72-73	glucan endo-1,3-beta-glucosidase, acidic-like	Nicotiana tabacum	217-235
11015193-3	2000	Conformational changes in Frq1 due to N-myristoylation and Ca(2+) binding were assessed by nuclear magnetic resonance (NMR), fluorescence, and equilibrium Ca(2+)-binding measurements.	Nitrogen	38-39	frequenin	Saccharomyces cerevisiae S288C	26-30
10956629-5	2000	However, there was a slight increase in protein-associated 3-nitrotyrosine in CF sputum compared with controls, reflecting the formation of reactive nitrogen intermediates, possibly through MPO-catalyzed oxidation of NO(2)(-).	Nitrogen	149-157	myeloperoxidase	Homo sapiens	190-193
11042968-2	2000	Analysis of redox reactions of the NH4+ reversible NO3- equilibrium in agrocenoses of gray forest soil has shown that the additional introduction of nitrogen fertilizers is undesirable both from the economical and ecological points of view, since the dominating process occurring with the loss of nitrogen from the soil in the form of gaseous compounds is thermodynamically most preferred.	Nitrogen	149-157	NBL1, DAN family BMP antagonist	Homo sapiens	51-54
10988251-1	2000	The role of the carbohydrates for the structure and functions of the plasma and tissue protein alpha1-microglobulin (alpha1m) was investigated by deletion of the sites for N-glycosylation by site-directed mutagenesis (N17,96--&gt;Q).	Nitrogen	172-173	pregnancy-zone protein	Rattus norvegicus	117-124
10988252-1	2000	The human epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein having 11 potential N-glycosylation sites in its extracellular domain.	Nitrogen	102-103	epidermal growth factor receptor	Homo sapiens	10-42
10988252-1	2000	The human epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein having 11 potential N-glycosylation sites in its extracellular domain.	Nitrogen	102-103	epidermal growth factor receptor	Homo sapiens	44-48
11042968-2	2000	Analysis of redox reactions of the NH4+ reversible NO3- equilibrium in agrocenoses of gray forest soil has shown that the additional introduction of nitrogen fertilizers is undesirable both from the economical and ecological points of view, since the dominating process occurring with the loss of nitrogen from the soil in the form of gaseous compounds is thermodynamically most preferred.	Nitrogen	297-305	NBL1, DAN family BMP antagonist	Homo sapiens	51-54
11030551-1	2000	Glutamine synthetase (GS) catalyses the formation of glutamine (a major form of nitrogen transport in plants) in an ATP-dependent reaction using ammonium and glutamate.	Nitrogen	80-88	glutamine synthetase	Nicotiana tabacum	0-20
10974054-7	2000	Vitrified molecules of apoB were obtained by plunging a thin fluid layer of protein adhered to a holey carbon-coated grid into supercooled ethane and by preserving the molecules in liquid nitrogen.	Nitrogen	188-196	apolipoprotein B	Homo sapiens	23-27
10859315-6	2000	(1)H-(15)N correlation NMR spectroscopy indicated that an extended groove in the eotaxin surface, whose edges are defined by the N-loop, 3(10)-helical turn, and beta(2)-beta(3) hairpin, is the most likely binding surface for CCR3-(1-35).	Nitrogen	9-10	C-C motif chemokine ligand 11	Homo sapiens	81-88
10942561-3	2000	Very significant supplementary information provided by UV-visible absorption, ESR, and resonance Raman spectra of PTH(+*) and PTH(2+), which were obtained by oxidation of PTH with lead tetraacetate, not only confirmed the two-step mono-electron-transfer mechanism proposed for interpretation of electron-transfer processes in PTH/semiconductor systems but also demonstrated that the two successive electron-transfer steps were corresponding to the removal of a p-electron at the nitrogen atom and a p-electron at the sulfur atom in the PTH molecule, respectively.	Nitrogen	479-487	parathyroid hormone	Homo sapiens	114-117
10942561-3	2000	Very significant supplementary information provided by UV-visible absorption, ESR, and resonance Raman spectra of PTH(+*) and PTH(2+), which were obtained by oxidation of PTH with lead tetraacetate, not only confirmed the two-step mono-electron-transfer mechanism proposed for interpretation of electron-transfer processes in PTH/semiconductor systems but also demonstrated that the two successive electron-transfer steps were corresponding to the removal of a p-electron at the nitrogen atom and a p-electron at the sulfur atom in the PTH molecule, respectively.	Nitrogen	479-487	parathyroid hormone	Homo sapiens	126-129
10942561-3	2000	Very significant supplementary information provided by UV-visible absorption, ESR, and resonance Raman spectra of PTH(+*) and PTH(2+), which were obtained by oxidation of PTH with lead tetraacetate, not only confirmed the two-step mono-electron-transfer mechanism proposed for interpretation of electron-transfer processes in PTH/semiconductor systems but also demonstrated that the two successive electron-transfer steps were corresponding to the removal of a p-electron at the nitrogen atom and a p-electron at the sulfur atom in the PTH molecule, respectively.	Nitrogen	479-487	parathyroid hormone	Homo sapiens	126-129
10942561-3	2000	Very significant supplementary information provided by UV-visible absorption, ESR, and resonance Raman spectra of PTH(+*) and PTH(2+), which were obtained by oxidation of PTH with lead tetraacetate, not only confirmed the two-step mono-electron-transfer mechanism proposed for interpretation of electron-transfer processes in PTH/semiconductor systems but also demonstrated that the two successive electron-transfer steps were corresponding to the removal of a p-electron at the nitrogen atom and a p-electron at the sulfur atom in the PTH molecule, respectively.	Nitrogen	479-487	parathyroid hormone	Homo sapiens	126-129
10942561-3	2000	Very significant supplementary information provided by UV-visible absorption, ESR, and resonance Raman spectra of PTH(+*) and PTH(2+), which were obtained by oxidation of PTH with lead tetraacetate, not only confirmed the two-step mono-electron-transfer mechanism proposed for interpretation of electron-transfer processes in PTH/semiconductor systems but also demonstrated that the two successive electron-transfer steps were corresponding to the removal of a p-electron at the nitrogen atom and a p-electron at the sulfur atom in the PTH molecule, respectively.	Nitrogen	479-487	parathyroid hormone	Homo sapiens	126-129
11030551-3	2000	In order to understand the role of GS isoforms in the remobilization of leaf nitrogen, we studied the localization of GS isoenzymes during natural senescence of tobacco (Nicotiana tabacum L.) leaves.	Nitrogen	77-85	glutamine synthetase	Nicotiana tabacum	35-37
10991527-1	2000	We find that nitrogen becomes totally opaque above 150 GPa, accompanied by the disappearance of Raman and IR vibrational excitations, while new broad IR and Raman bands become visible.	Nitrogen	13-21	glycophorin A (MNS blood group)	Homo sapiens	55-58
11026737-4	2000	At 10 microM PER, a concentration consistent with anticipated in vivo liver concentrations, CYP3A4 and CYP2C9 contributed 50% and 35%, respectively, to PER-N-demethylation.	Nitrogen	156-157	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	92-98
10801787-8	2000	mu-Protocadherin contains both N and O glycosylations.	Nitrogen	31-32	cadherin related family member 5	Homo sapiens	0-16
10854422-7	2000	In addition, ASP-1 contains conserved, potential disulfide bond-forming cysteine residues and N-glycosylation sites.	Nitrogen	94-95	Aspartic protease 1	Caenorhabditis elegans	13-18
11051050-3	2000	In this study, Phex expression was measured in 6-wk-old normal B6C3H male and female mice and in 135 g Sprague-Dawley rats fed a normal phosphate diet or a low phosphate diet with deionized water ad libitum for 7 d. The animals were then anesthetized, and a variety of organs were collected and frozen in liquid nitrogen.	Nitrogen	312-320	phosphate regulating endopeptidase homolog, X-linked	Mus musculus	15-19
10903131-4	2000	In addition, we have found that a wide variety of structurally diverse N-appended alcohol-containing residues, including tyrosine, serve as substrates for the PKC alpha, betaII and gamma isoforms.	Nitrogen	71-72	protein kinase C alpha	Homo sapiens	159-186
10887202-5	2000	Here we demonstrate that BACE is an N-glycosylated integral membrane protein that undergoes constitutive N-terminal processing in the Golgi apparatus.	Nitrogen	36-37	beta-secretase 1	Homo sapiens	25-29
10971113-12	2000	It was indicated that the N-linked glycan moieties such as that of Gly m Bd 28K may be one of the common IgE-reactive determinants distributed in various plant food proteins.	Nitrogen	26-27	immunoglobulin heavy constant epsilon	Homo sapiens	105-108
10867322-0	2000	Nitrogen metabolism and renal function in the dik-dik antelope (Rhynchotragus kirkii).	Nitrogen	0-8	receptor interacting serine/threonine kinase 4	Homo sapiens	46-49
10867322-0	2000	Nitrogen metabolism and renal function in the dik-dik antelope (Rhynchotragus kirkii).	Nitrogen	0-8	receptor interacting serine/threonine kinase 4	Homo sapiens	50-53
10867322-2	2000	Dik-dik antelope remained in nitrogen balance even when fed a diet low in protein and high in fibre.	Nitrogen	29-37	receptor interacting serine/threonine kinase 4	Homo sapiens	0-3
10867322-2	2000	Dik-dik antelope remained in nitrogen balance even when fed a diet low in protein and high in fibre.	Nitrogen	29-37	receptor interacting serine/threonine kinase 4	Homo sapiens	4-7
10867322-8	2000	It is concluded that the metabolic nitrogen economy of the dik-dik antelope is qualitatively similar to that of other domestic and wild ruminants.	Nitrogen	35-43	receptor interacting serine/threonine kinase 4	Homo sapiens	59-62
10867322-8	2000	It is concluded that the metabolic nitrogen economy of the dik-dik antelope is qualitatively similar to that of other domestic and wild ruminants.	Nitrogen	35-43	receptor interacting serine/threonine kinase 4	Homo sapiens	63-66
10904086-9	2000	RESULTS: Sulindac and NS-398 progressively increased 15-LOX-1 protein expression in RKO cells (at 24, 48, and 72 hours) in association with subsequent growth inhibition and apoptosis.	Nitrogen	22-24	arachidonate 15-lipoxygenase	Homo sapiens	53-61
10891485-7	2000	These findings argue that nitrogen limitation governs Rim11p/Mck1p-dependent phosphorylation of Ume6p, which in turn is required for Ume6p-Ime1p interaction and meiotic gene activation.	Nitrogen	26-34	serine/threonine/tyrosine protein kinase MCK1	Saccharomyces cerevisiae S288C	61-66
11038011-9	2000	Finally, the mutant vasopressin gene lacking the N-linked glycosylation site in glycopeptide had no effect on vasopressin expression.	Nitrogen	49-50	arginine vasopressin	Homo sapiens	20-31
10898952-0	2000	The heme-containing N-fragment (residues 1-56) of cytochrome c is a bis-histidine functional system.	Nitrogen	20-21	cytochrome c, somatic	Homo sapiens	50-62
10893314-11	2000	Molecular modeling studies on 12a suggested that the protonated N-17 and guanidinium groups of GNTI are associated with Asp138 (TM3) and Glu297 (TM6), respectively, while the phenolic hydroxyl may be involved in donor-acceptor interactions with the imidazole ring of His291.	Nitrogen	64-65	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	95-99
10873668-7	2000	The lack of the chemokine binding was not likely to be due to the lack of glycosylation of the Fy/GPA, since IL-8 was effectively bound to de-N-glycosylated erythrocytes.	Nitrogen	142-143	C-X-C motif chemokine ligand 8	Homo sapiens	109-113
10856884-8	2000	Rat PLP-J cDNA encodes for a predicted 211 amino acid protein containing a 29 amino acid signal peptide and two putative N-linked glycosylation sites, whereas the mouse PLP-J cDNA encodes for a 212 amino acid protein containing a 29 amino acid signal peptide with a single N-linked glycosylation site.	Nitrogen	12-13	prolactin family 3, subfamily C, member 1	Rattus norvegicus	4-9
10861210-1	2000	The human erythrocyte anion exchanger (AE)1 (Band 3) contains a single complex N-linked oligosaccharide that is attached to Asn(642) in the fourth extracellular loop of this polytopic membrane protein, while other isoforms (AE2, AE3 and trout AE1) are N-glycosylated on the preceding extracellular loop.	Nitrogen	79-80	solute carrier family 4 member 3	Homo sapiens	229-232
10864452-0	2000	The status of half-cystine residues and locations of N-glycosylated asparagine residues in human eosinophil peroxidase.	Nitrogen	53-54	eosinophil peroxidase	Homo sapiens	97-118
10921586-15	2000	E-selectin deficient mice showed lower creatinine and blood urea nitrogen concentrations than wild-type mice at 24 and 48 hrs (a reduction of 60% to 80%).	Nitrogen	65-73	selectin, endothelial cell	Mus musculus	0-10
10856884-8	2000	Rat PLP-J cDNA encodes for a predicted 211 amino acid protein containing a 29 amino acid signal peptide and two putative N-linked glycosylation sites, whereas the mouse PLP-J cDNA encodes for a 212 amino acid protein containing a 29 amino acid signal peptide with a single N-linked glycosylation site.	Nitrogen	121-122	prolactin family 3, subfamily C, member 1	Rattus norvegicus	4-9
10861906-10	2000	We also found that environmental conditions for meiosis finely regulate the transcript levels of KIN28 and CCL1, such that nitrogen starvation first elevates them but subsequent alkalization of medium decreases them.	Nitrogen	123-131	TFIIH complex kinase subunit CCL1	Saccharomyces cerevisiae S288C	107-111
10889259-4	2000	In contrast to the corresponding enzymes from animals, all plant GnTI sequences identified are characterized by a much shorter hydrophobic membrane anchor and contain one putative N-glycosylation site that is conserved in potato and tobacco, but differs in Arabidopsis.	Nitrogen	180-181	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Solanum tuberosum	65-69
10945152-4	2000	Insulin 1) reduces glycosuria and its caloric expenditure; 2) stimulates the stockage of fatty acids into triglycerides in adipose tissue, thus favoring an increase in adipose mass; 3) yields a positive nitrogen balance through an inhibition of muscle proteolysis, thus favoring an increase in lean mass.	Nitrogen	203-211	insulin	Homo sapiens	0-7
10766755-0	2000	Structural requirements for N-trimethylation of lysine 115 of calmodulin.	Nitrogen	28-29	calmodulin 1	Homo sapiens	62-72
10773339-0	2000	Distribution of the Mo-enzymes aldehyde oxidase, xanthine dehydrogenase and nitrate reductase in maize (Zea mays L.) nodal roots as affected by nitrogen and salinity.	Nitrogen	144-152	xanthine dehydrogenase	Zea mays	49-71
10864762-0	2000	Organoyttrium-catalyzed sequential Cyclization/Silylation reactions of nitrogen-heteroaromatic dienes demonstrating "Aryl-Directed" regioselectivity The reaction of 1-allyl-2-vinyl-1H-pyrroles and 1-allyl-2-vinyl-1H-indoles with arylsilanes in the presence of catalytic [Cp(TMS)(2)Y(&amp;mgr;-Me)](2) leads to highly selective cyclization/silylation events.	Nitrogen	71-79	PYD and CARD domain containing	Homo sapiens	274-277
10828967-1	2000	The receptor for parathyroid hormone (PTH) and PTH-related peptide (PTHrP) is a G-protein-coupled receptor with four potential sites for N-linked glycosylation.	Nitrogen	137-138	parathyroid hormone	Rattus norvegicus	17-36
10809695-0	2000	In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex.	Nitrogen	107-115	histone deacetylase RPD3	Saccharomyces cerevisiae S288C	177-181
10877394-0	2000	Estimation of the flow of microbial nitrogen to the duodenum using milk uric acid or allantoin.	Nitrogen	36-44	Weaning weight-maternal milk	Bos taurus	67-71
10877394-3	2000	The coefficient of determination for individual experiments for the relationship between microbial nitrogen flow and allantoin or uric acid excretion in milk ranged from -0.01 to 0.77 and -0.06 to 0.22 respectively.	Nitrogen	99-107	Weaning weight-maternal milk	Bos taurus	153-157
10877394-4	2000	Across all experiments, the coefficients of determination between microbial nitrogen flow and allantoin or uric acid excretion in milk were r2 = 0.09 and 0.01 respectively.	Nitrogen	76-84	Weaning weight-maternal milk	Bos taurus	130-134
10877394-5	2000	Milk allantoin output was used to develop a prediction equation estimating microbial nitrogen flow to the duodenum.	Nitrogen	85-93	Weaning weight-maternal milk	Bos taurus	0-4
10825749-6	2000	The 55 MeV protons and 32 MeV/nucleon nitrogen ions were each about 10 times more mutagenic per unit dose at the CD59 locus in A(L)C cells than in A(L) cells.	Nitrogen	38-46	CD59 molecule (CD59 blood group)	Homo sapiens	113-117
10828967-1	2000	The receptor for parathyroid hormone (PTH) and PTH-related peptide (PTHrP) is a G-protein-coupled receptor with four potential sites for N-linked glycosylation.	Nitrogen	137-138	parathyroid hormone	Rattus norvegicus	38-41
10828967-4	2000	The results revealed that all four potential N-glycosylation sites in the PTH/PTHrP receptor are glycosylated.	Nitrogen	45-46	parathyroid hormone	Rattus norvegicus	74-77
10828967-7	2000	These data indicate important roles for N-linked glycosylation in PTH/PTHrP receptor functions.	Nitrogen	40-41	parathyroid hormone	Rattus norvegicus	66-69
10794736-1	2000	alpha-Lactalbumin (alpha-LA) is a regulatory protein by which the mammalian beta1,4-galactosyltransferase (beta1,4-galT) is induced to utilize glucose as an acceptor instead of N-acetylglucosamine (GlcNAc) during lactose synthesis in mammary gland.	Nitrogen	177-178	lactalbumin alpha	Homo sapiens	0-17
10794736-1	2000	alpha-Lactalbumin (alpha-LA) is a regulatory protein by which the mammalian beta1,4-galactosyltransferase (beta1,4-galT) is induced to utilize glucose as an acceptor instead of N-acetylglucosamine (GlcNAc) during lactose synthesis in mammary gland.	Nitrogen	177-178	lactalbumin alpha	Homo sapiens	19-27
10788330-3	2000	In the nitrogen-fixing bacteria Azotobacter vinelandii the rhdA gene has been identified and the encoded protein functionally characterized as a rhodanese.	Nitrogen	7-15	thiosulfate sulfurtransferase	Bos taurus	145-154
10799523-0	2000	Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae.	Nitrogen	0-8	glutathione peroxidase	Saccharomyces cerevisiae S288C	95-100
10799523-2	2000	Ure2p, which is not a GATA family member, inhibits Gln3p/Gat1p from functioning in the presence of good nitrogen sources.	Nitrogen	104-112	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
10799523-5	2000	Further, overproduction of Ure2p nearly eliminates NCR-sensitive transcription under derepressive growth conditions, i.e. with proline as the sole nitrogen source.	Nitrogen	147-155	glutathione peroxidase	Saccharomyces cerevisiae S288C	27-32
10872590-6	2000	The ensuing RDA fragmentation easily identifies which of the two product ions contains the deuterium, thereby allowing us to assign the site of N-acetylation as the amino group on ring C (the 4" position) of DAF.	Nitrogen	144-145	CD55 molecule (Cromer blood group)	Rattus norvegicus	208-211
10823661-5	2000	Furthermore, since the stability of N-glycosylated proteins is known to be regulated by lectin family chaperones, such as calnexin, a type I transmembrane protein located in the endoplasmic reticulum (ER), and calreticulin, a soluble protein in the ER lumen, the effect of the processing inhibitors on the interaction of IFN-gamma with calnexin and calreticulin was investigated.	Nitrogen	36-37	calreticulin	Homo sapiens	210-222
10807583-6	2000	Cellubrevin, an analog of the vesicle soluble N-ethyl malemide-sensitive factor attachment protein (SNAP) receptor (v-SNARE) synaptobrevin, is highly enriched in H(+)-ATPase-rich cells of the epididymis and vas deferens, and tetanus toxin treatment markedly inhibited bafilomycin-sensitive proton secretion by 64.3+/-9.0% in the proximal vas deferens.	Nitrogen	46-47	vesicle transport through interaction with t-SNAREs 1B	Homo sapiens	116-123
10823661-5	2000	Furthermore, since the stability of N-glycosylated proteins is known to be regulated by lectin family chaperones, such as calnexin, a type I transmembrane protein located in the endoplasmic reticulum (ER), and calreticulin, a soluble protein in the ER lumen, the effect of the processing inhibitors on the interaction of IFN-gamma with calnexin and calreticulin was investigated.	Nitrogen	36-37	interferon gamma	Homo sapiens	321-330
10843221-0	2000	Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation.	Nitrogen	15-16	nitric oxide synthase 2	Homo sapiens	62-83
10823661-5	2000	Furthermore, since the stability of N-glycosylated proteins is known to be regulated by lectin family chaperones, such as calnexin, a type I transmembrane protein located in the endoplasmic reticulum (ER), and calreticulin, a soluble protein in the ER lumen, the effect of the processing inhibitors on the interaction of IFN-gamma with calnexin and calreticulin was investigated.	Nitrogen	36-37	calreticulin	Homo sapiens	349-361
10810088-4	2000	Bovine CINF, characterized by increased blood urea nitrogen, creatinine, and urinary proteins, leads to lethality before puberty, usually within the first 6 months or year of life.	Nitrogen	51-59	CINF	Bos taurus	7-11
10905635-1	2000	Glycosyltransferase cDNAs contain a variable number of potential N-glycosylation sites.	Nitrogen	22-23	protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2	Mus musculus	0-19
10749666-4	2000	In the present study, examination of SERP-1 glycosylation-site mutants showed that the N-linked glycosylation of Asn(172) was essential for SERP-1 secretion, whereas mutation of Asn(99) decreased secretion efficiency, indicating that N-linked glycosylation plays an essential role in the processing and trafficking of SERP-1.	Nitrogen	87-88	stress associated endoplasmic reticulum protein 1	Homo sapiens	37-43
10766842-10	2000	The N-glycosylation in the C-terminal region was found to be important for secretion of TPO.	Nitrogen	4-5	thrombopoietin	Homo sapiens	88-91
10749666-4	2000	In the present study, examination of SERP-1 glycosylation-site mutants showed that the N-linked glycosylation of Asn(172) was essential for SERP-1 secretion, whereas mutation of Asn(99) decreased secretion efficiency, indicating that N-linked glycosylation plays an essential role in the processing and trafficking of SERP-1.	Nitrogen	87-88	stress associated endoplasmic reticulum protein 1	Homo sapiens	140-146
10749666-4	2000	In the present study, examination of SERP-1 glycosylation-site mutants showed that the N-linked glycosylation of Asn(172) was essential for SERP-1 secretion, whereas mutation of Asn(99) decreased secretion efficiency, indicating that N-linked glycosylation plays an essential role in the processing and trafficking of SERP-1.	Nitrogen	87-88	stress associated endoplasmic reticulum protein 1	Homo sapiens	140-146
10784427-5	2000	Methyl quadrangularates A (30) and N (32), norquadrangularic acid B (31) and vitexin (40) also showed potent inhibition on TNF-alpha-induced cell death with IC50 values of 45.7, 89.3, 67.6 and 40.1 microM, respectively.	Nitrogen	35-36	tumor necrosis factor	Mus musculus	123-132
15263174-2	2000	The Co(III) ion is six-coordinate in a nearly octahedral environment provided by one Cl atom, four N atoms of the bridging ligand, and one O atom.	Nitrogen	99-100	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	4-11
10771285-6	2000	The additive contribution (75.3%) of human CYP3A and CYP2C to diazepam N-demethylation was also observed in the presence of both anti-CYP3A4/5 and anti-CYP2C8/9/19 monoclonal antibodies.	Nitrogen	71-72	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	43-48
10771285-6	2000	The additive contribution (75.3%) of human CYP3A and CYP2C to diazepam N-demethylation was also observed in the presence of both anti-CYP3A4/5 and anti-CYP2C8/9/19 monoclonal antibodies.	Nitrogen	71-72	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	134-140
10744677-2	2000	We have determined the solution structure of (15)N-labeled Long-[Arg(3)]-IGF-I using high resolution NMR and restrained molecular dynamics techniques to a precision of 0.82 +/- 0.28 A root mean square deviation for the backbone heavy atoms in the three alpha-helices and 3.5 +/- 0.9 A root mean square deviation for all backbone heavy atoms excluding the 8 N-terminal residues and the 8 C-terminal eight residues.	Nitrogen	49-50	insulin like growth factor 1	Homo sapiens	73-78
10692561-0	2000	Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide.	Nitrogen	63-64	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	31-37
10692561-3	2000	Analysis of a panel of fifteen human P450 cDNAs in the baculovirus expression system ("Supersomes") demonstrated that CYP3A4 exhibited the highest N-dechloroethylation activity toward both CPA and IFA, whereas CYP2B6 displayed high N-dechloroethylation activity toward IFA, but not CPA.	Nitrogen	44-45	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	118-124
10692561-3	2000	Analysis of a panel of fifteen human P450 cDNAs in the baculovirus expression system ("Supersomes") demonstrated that CYP3A4 exhibited the highest N-dechloroethylation activity toward both CPA and IFA, whereas CYP2B6 displayed high N-dechloroethylation activity toward IFA, but not CPA.	Nitrogen	147-148	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	118-124
10692561-5	2000	With CPA as substrate, CYP3A4 was shown to catalyze &gt;/=95% of liver microsomal N-dechloroethylation, whereas with IFA as substrate, CYP3A4 catalyzed an average of approximately 70% of liver microsomal N-dechloroethylation (range = 40-90%), with the balance of this activity catalyzed by CYP2B6 (range = 10-70%, dependent on the CYP2B6 content of the liver).	Nitrogen	82-83	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	23-29
10692561-5	2000	With CPA as substrate, CYP3A4 was shown to catalyze &gt;/=95% of liver microsomal N-dechloroethylation, whereas with IFA as substrate, CYP3A4 catalyzed an average of approximately 70% of liver microsomal N-dechloroethylation (range = 40-90%), with the balance of this activity catalyzed by CYP2B6 (range = 10-70%, dependent on the CYP2B6 content of the liver).	Nitrogen	82-83	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	135-141
10692561-5	2000	With CPA as substrate, CYP3A4 was shown to catalyze &gt;/=95% of liver microsomal N-dechloroethylation, whereas with IFA as substrate, CYP3A4 catalyzed an average of approximately 70% of liver microsomal N-dechloroethylation (range = 40-90%), with the balance of this activity catalyzed by CYP2B6 (range = 10-70%, dependent on the CYP2B6 content of the liver).	Nitrogen	204-205	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	23-29
10784439-1	2000	Previous studies on the structural development of tumor necrosis factor alpha (TNF-alpha) production regulators derived from thalidomide (N-alpha-phthalimidoglutarimide) revealed that a hydrophobic substituent at the nitrogen atom of the phthalimide ring is critical for potent activity.	Nitrogen	217-225	tumor necrosis factor	Homo sapiens	50-77
10784439-1	2000	Previous studies on the structural development of tumor necrosis factor alpha (TNF-alpha) production regulators derived from thalidomide (N-alpha-phthalimidoglutarimide) revealed that a hydrophobic substituent at the nitrogen atom of the phthalimide ring is critical for potent activity.	Nitrogen	217-225	tumor necrosis factor	Homo sapiens	79-88
10716671-11	2000	This was shown to be N-glycosylated TFF2 using the endoglycosidase, peptide-N-Gycosidase F. The majority of TFF2 in normal gastric mucosa was also glycosylated.	Nitrogen	21-22	trefoil factor 2	Homo sapiens	36-40
10826490-4	2000	The mammalian oligosaccharyltransferase (OST) is a protein complex that effects the cotranslational N-glycosylation of newly synthesized polypeptides, and is composed of at least four rough ER-specific membrane proteins: ribophorins I and II (RI and RII), OST48, and Dadl.	Nitrogen	100-101	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	14-39
10826490-4	2000	The mammalian oligosaccharyltransferase (OST) is a protein complex that effects the cotranslational N-glycosylation of newly synthesized polypeptides, and is composed of at least four rough ER-specific membrane proteins: ribophorins I and II (RI and RII), OST48, and Dadl.	Nitrogen	100-101	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	41-44
10716671-11	2000	This was shown to be N-glycosylated TFF2 using the endoglycosidase, peptide-N-Gycosidase F. The majority of TFF2 in normal gastric mucosa was also glycosylated.	Nitrogen	21-22	trefoil factor 2	Homo sapiens	108-112
10716671-12	2000	CONCLUSIONS: Human TFF2 is glycosylated via an N-linkage, presumably on Asn(15) which forms part of the single consensus site for N-glycosylation in human TFF2.	Nitrogen	2-3	trefoil factor 2	Homo sapiens	19-23
10716671-12	2000	CONCLUSIONS: Human TFF2 is glycosylated via an N-linkage, presumably on Asn(15) which forms part of the single consensus site for N-glycosylation in human TFF2.	Nitrogen	2-3	trefoil factor 2	Homo sapiens	155-159
10708854-1	2000	As a highly regulated enzyme at the core of nitrogen metabolism, glutamine synthetase has been studied intensively.	Nitrogen	44-52	glutamate-ammonia ligase	Homo sapiens	65-85
10704441-4	2000	We first demonstrated that b(5) can acquire a transmembrane topology posttranslationally, and then used two tagged versions of b(5), N-glyc and O-glyc b(5), containing potential N- and O-glycosylation sites, respectively, at the COOH-terminal lumenal extremity, to discriminate between retention and retrieval mechanisms.	Nitrogen	133-134	glycoprotein hormone subunit beta 5	Homo sapiens	127-131
10637365-4	2000	It is concluded that hydrophobicity and the presence of an ionizable nitrogen are the pre-requisites for the inhibitors to interact with AChE.	Nitrogen	69-77	acetylcholinesterase (Cartwright blood group)	Homo sapiens	137-141
10704441-4	2000	We first demonstrated that b(5) can acquire a transmembrane topology posttranslationally, and then used two tagged versions of b(5), N-glyc and O-glyc b(5), containing potential N- and O-glycosylation sites, respectively, at the COOH-terminal lumenal extremity, to discriminate between retention and retrieval mechanisms.	Nitrogen	133-134	glycoprotein hormone subunit beta 5	Homo sapiens	127-131
10750102-0	2000	Milk urea nitrogen and infertility in Florida Holstein cows.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
10691991-8	2000	Both glycans are xylose containing biantennary complex types that share the common core structural unit, Man1--&gt;6(Man1--&gt;3) (Xyl1--&gt;2)Man1--&gt;4GlcNAc1--&gt;4(Fuc1--&gt;3)GlcNAc for the major form, with an additional N-acetylglucosamine residue being linked, in the minor form, to one of the terminal mannose units of the core structure.	Nitrogen	157-158	LEM domain containing 3	Homo sapiens	105-109
10691991-8	2000	Both glycans are xylose containing biantennary complex types that share the common core structural unit, Man1--&gt;6(Man1--&gt;3) (Xyl1--&gt;2)Man1--&gt;4GlcNAc1--&gt;4(Fuc1--&gt;3)GlcNAc for the major form, with an additional N-acetylglucosamine residue being linked, in the minor form, to one of the terminal mannose units of the core structure.	Nitrogen	157-158	LEM domain containing 3	Homo sapiens	117-121
10691991-8	2000	Both glycans are xylose containing biantennary complex types that share the common core structural unit, Man1--&gt;6(Man1--&gt;3) (Xyl1--&gt;2)Man1--&gt;4GlcNAc1--&gt;4(Fuc1--&gt;3)GlcNAc for the major form, with an additional N-acetylglucosamine residue being linked, in the minor form, to one of the terminal mannose units of the core structure.	Nitrogen	157-158	LEM domain containing 3	Homo sapiens	117-121
10750102-1	2000	The objective of this study was to evaluate the association between milk urea nitrogen (MUN) and risk of nonpregnancy after first breeding in a commercial dairy herd in Florida.	Nitrogen	78-86	Weaning weight-maternal milk	Bos taurus	68-72
10808272-5	2000	Using this system, the role of N-glycosylation in pIgA-pIgR binding was examined.	Nitrogen	31-32	phosphatidylinositol glycan anchor biosynthesis, class A	Mus musculus	50-54
10752606-2	2000	The first 65 amino acids, which are dispensable for the cellular function of Ure2p in nitrogen metabolism, are necessary and sufficient for [URE3] (Masison &amp; Wickner, 1995), leading to designation of this domain as the Ure2 prion domain (UPD).	Nitrogen	86-94	glutathione peroxidase	Saccharomyces cerevisiae S288C	77-81
10879678-2	2000	The present work confirms that cytochalasin E inhibits SGLT1 activity through cytoskeleton disruption, showing that in anaerobic conditions (N2 bubbling), which implies low cytosolic ATP levels, the inhibition is not observed.	Nitrogen	141-143	solute carrier family 5 member 1	Homo sapiens	55-60
10720448-10	2000	CONCLUSION: Levels of TNF-alpha mRNA in the brain were enhanced according to the length of the wound probably because of greater neural stimuli from the wound site, and this elevation was involved in the greater nitrogen loss.	Nitrogen	212-220	tumor necrosis factor	Mus musculus	22-31
10752644-6	2000	Subsequently, it was determined that AMA, DAA and MPA also underwent CYP2D6-catalysed N-dealkylation.	Nitrogen	86-87	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	69-75
10681575-9	2000	We find Aut7p expression is induced by nitrogen starvation.	Nitrogen	39-47	ubiquitin-like protein ATG8	Saccharomyces cerevisiae S288C	8-13
10675553-6	2000	AtAMT2 was expressed more highly in shoots than roots and was subject to nitrogen regulation.	Nitrogen	73-81	ammonium transporter 2	Arabidopsis thaliana	0-6
10675514-7	2000	However, dog and bovine AQP1 have only one N-glycosylation site, while two glycosylation sites were found in human and rodent AQP1.	Nitrogen	43-44	aquaporin 1	Bos taurus	24-28
10667916-1	2000	P-glycoprotein (P-gp), the product of human MDR1 gene, which functions as an ATP-dependent drug efflux pump, is N-linked glycosylated at asparagine residues 91, 94, and 99 located within the first extracellular loop.	Nitrogen	112-113	ATP binding cassette subfamily B member 1	Homo sapiens	0-14
10640391-4	2000	Based on activities of chemically modified heparins, binding to TSP1 depended primarily on 2-N- and 6-O-sulfation of glucosamine and to a lesser degree on 2,3-O-sulfation and the carboxyl residues of the uronic acids.	Nitrogen	93-94	thrombospondin 1	Homo sapiens	64-68
10667916-1	2000	P-glycoprotein (P-gp), the product of human MDR1 gene, which functions as an ATP-dependent drug efflux pump, is N-linked glycosylated at asparagine residues 91, 94, and 99 located within the first extracellular loop.	Nitrogen	112-113	ATP binding cassette subfamily B member 1	Homo sapiens	16-20
10667916-1	2000	P-glycoprotein (P-gp), the product of human MDR1 gene, which functions as an ATP-dependent drug efflux pump, is N-linked glycosylated at asparagine residues 91, 94, and 99 located within the first extracellular loop.	Nitrogen	112-113	ATP binding cassette subfamily B member 1	Homo sapiens	44-48
11310976-5	2000	In addition, glycophorin A from erythrocytes of a patient with CDA II but not CDA I exhibited a significant deficit of mannose and N-acetylglucosamine suggesting that its N-glycosylation site was also partly unglycosylated.	Nitrogen	131-132	glycophorin A (MNS blood group)	Homo sapiens	13-26
10633045-4	2000	In each case, the nitrogen at position-1 of the quinazoline accepted a hydrogen bond from a backbone NH (CDK2, Leu-83; p38, Met-109) of the domain connector strand, and aromatic hydrogen atoms at C2 and C8 interacted with backbone carbonyl oxygen atoms of the peptide strand.	Nitrogen	18-26	mitogen-activated protein kinase 14	Homo sapiens	119-122
10761711-3	2000	Immunoprecipitation studies of human tumor cell lines revealed that FU-MK-1 recognizes a monomeric membrane glycoprotein with two forms, 40 kDa (major form) and 42 kDa (minor form), and with a molecular mass of 35 kDa following treatment with the N-glycosylation inhibitor tunicamycin.	Nitrogen	247-248	epithelial cell adhesion molecule	Homo sapiens	71-75
10961687-1	2000	Some sterically hindered N-substituted derivatives of daunorubicin are known to be poor substrates for NADH dehydrogenase, NADPH cytochrome P450 reductase and xanthine oxidase.	Nitrogen	25-26	cytochrome p450 oxidoreductase	Homo sapiens	123-154
10717383-3	2000	We show here that three different strains deficient in either the Ku80 (xrs-6) or DNA-PKcs (V-3, scid) component of DNA-PK are markedly sensitive (3.5- to 5-fold) to a group of DNA cross-linking agents, the nitrogen mustards (NMs) (melphalan and mechlorethamine) as compared to their parental cell line.	Nitrogen	207-215	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	82-90
10615066-0	2000	Effects of reactive oxygen and nitrogen metabolites on eotaxin-induced eosinophil chemotactic activity in vitro.	Nitrogen	31-39	C-C motif chemokine ligand 11	Homo sapiens	55-62
10717383-3	2000	We show here that three different strains deficient in either the Ku80 (xrs-6) or DNA-PKcs (V-3, scid) component of DNA-PK are markedly sensitive (3.5- to 5-fold) to a group of DNA cross-linking agents, the nitrogen mustards (NMs) (melphalan and mechlorethamine) as compared to their parental cell line.	Nitrogen	207-215	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	82-88
10717383-0	2000	The activity of the DNA-dependent protein kinase (DNA-PK) complex is determinant in the cellular response to nitrogen mustards.	Nitrogen	109-117	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	20-48
10617114-6	2000	To determine the possible activation of caspase-3 in NMDA-induced neuronal apoptosis, we used an affinity-labeling technique: Biotinylated N-acetyl-Asp-Glu-Val-Asp-aldehyde (DEVD.CHO) preferentially labels conformationally active caspase-3-like proteases, allowing us to visualize affinity-labeled caspases with streptavidin-fluorescein isothiocyanate under confocal microscopy.	Nitrogen	53-54	caspase 3	Homo sapiens	40-49
10717383-0	2000	The activity of the DNA-dependent protein kinase (DNA-PK) complex is determinant in the cellular response to nitrogen mustards.	Nitrogen	109-117	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	50-56
11125490-0	2000	B cell production and turnover in CBA/Ca, CBA/N and CBA/N-bcl-2 transgenic mice: xid-mediated failure among pre B cells is unaltered by bcl-2 overexpression.	Nitrogen	56-57	BCL2 apoptosis regulator	Homo sapiens	58-63
11045901-2	2000	Two groups of compounds with different lengths of alkyl chains connecting the amine nitrogen and the central oxygen showed a one order difference in their 5-HT2 receptor binding affinity.	Nitrogen	84-92	5-hydroxytryptamine receptor 2A	Homo sapiens	155-169
10965220-0	2000	N-glycosylated variants of growth hormone in human pituitary extracts.	Nitrogen	0-1	growth hormone 1	Homo sapiens	27-41
10601814-10	2000	This inhibitory effect was reversed by cotreatment with the 180 microg/h dose of IL-1ra (to 82.5 +/- 3.8% by 5 h; NS vs. saline) but not with the lower doses.	Nitrogen	114-116	interleukin 1 receptor type 1	Homo sapiens	81-87
11215047-2	2000	NO3- was restored by using cadmium column assay and NO2- measured by heavy nitrogen assay.	Nitrogen	75-83	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
10743657-9	2000	In leaves, the reciprocally expressed transporters LeAMT1;2 and LeAMT1;3 are supposed to play different roles in N metabolism, NH4+ uptake and/or NH3 retrieval during photorespiration.	Nitrogen	113-114	ammonium transporter 1 member 2	Solanum lycopersicum	51-59
10743657-9	2000	In leaves, the reciprocally expressed transporters LeAMT1;2 and LeAMT1;3 are supposed to play different roles in N metabolism, NH4+ uptake and/or NH3 retrieval during photorespiration.	Nitrogen	113-114	ammonium transporter 1 member 3	Solanum lycopersicum	64-72
10619430-4	1999	Together with the pattern of SN1 expression, these unusual properties suggest novel physiological roles for system N in nitrogen metabolism and synaptic transmission.	Nitrogen	120-128	solute carrier family 38 member 3	Homo sapiens	29-32
12541453-4	2000	It is shown that the PMV CA phase has some special selectivities: 1) It has different selectivity from C18 and C8 phase because the PMV CA phase may form diploe interaction, pi-electron interaction and hydrogen bonding interaction (with the nitrogen atom and oxygen atom on the phase) with solutes owing to its polar aromatic thiazole ring and polar ester bond etc.	Nitrogen	241-249	Bardet-Biedl syndrome 9	Homo sapiens	103-106
10606508-3	1999	Infected Chinese hamster ovary cells expressed N-glycosylated Kv1.1 and 1.2 alpha subunits (M(r) approximately 60 and 62 K) that assembled and bound [(125)I]-alphaDTX with high affinity; an appreciable proportion appeared on the cell surface, with Kv1.2 showing a 5-fold enrichment in a plasma membrane fraction.	Nitrogen	47-48	potassium voltage-gated channel subfamily A member 2	Homo sapiens	248-253
11671330-9	1999	The kinetics of nitrogen atom transfer from a series of 5,5"-disubstituted salophen nitrido complexes to PPh(3) have been studied in CH(3)CN at 25.0 degrees C by stopped-flow spectrophotometric method.	Nitrogen	16-24	caveolin 1	Homo sapiens	105-111
10604478-4	1999	Here we show that TOR prevents transcription of genes expressed upon nitrogen limitation by promoting the association of the GATA transcription factor GLN3 with the cytoplasmic protein URE2.	Nitrogen	69-77	glutathione peroxidase	Saccharomyces cerevisiae S288C	185-189
10617575-4	1999	TOR inhibition by rapamycin induces expression of nitrogen source utilization genes controlled by the Ure2 repressor and the transcriptional regulator Gln3, and globally represses ribosomal protein expression.	Nitrogen	50-58	glutathione peroxidase	Saccharomyces cerevisiae S288C	102-106
10617575-6	1999	We find that Ure2 is a phosphoprotein in vivo that is rapidly dephosphorylated in response to rapamycin or nitrogen limitation.	Nitrogen	107-115	glutathione peroxidase	Saccharomyces cerevisiae S288C	13-17
10601628-5	1999	The site of glycosylation is Asn(59), the only asparagine in the amino acid sequence contained in the N-glycosylation site consensus sequence, N-A-S. Ser(61), which is part of this site, is phosphorylated in OC-17 but not in OC-23 indicating that the two modifications are mutually exclusive.	Nitrogen	102-103	ovocleidin 17	Gallus gallus	208-213
10611304-5	1999	Poor nitrogen quality activates the nitrogen discrimination pathway, which is controlled by the complex of the transcriptional repressor Ure2p and activator Gln3p.	Nitrogen	5-13	glutathione peroxidase	Saccharomyces cerevisiae S288C	137-142
10611304-5	1999	Poor nitrogen quality activates the nitrogen discrimination pathway, which is controlled by the complex of the transcriptional repressor Ure2p and activator Gln3p.	Nitrogen	36-44	glutathione peroxidase	Saccharomyces cerevisiae S288C	137-142
10647213-0	1999	Effectiveness of ascorbate and ascorbate peroxidase in promoting nitrogen fixation in model systems.	Nitrogen	65-73	peroxidase	Glycine max	41-51
10600939-5	1999	Interestingly, in the adrenal gland and ovary, the rat Pkd2 protein was more heavily N-glycosylated than in the kidney and salivary gland.	Nitrogen	85-86	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	55-59
10660692-4	1999	Cells deficient in DNA-PK activity also exhibit hypersensitivity to genotoxic drugs such as cisplatin and nitrogen mustards.	Nitrogen	106-114	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	19-25
10587518-5	1999	Moreover, CCR1(-/-) mice developed more severe glomerulonephritis than did controls, with greater proteinuria and blood urea nitrogen, as well as a higher frequency of crescent formation.	Nitrogen	125-133	chemokine (C-C motif) receptor 1	Mus musculus	10-14
10567392-9	1999	These results indicate that human sPLA(2)-X is a unique N-glycosylated sPLA(2) that releases arachidonic acid from human myeloid leukemia cells more efficiently than sPLA(2)-IB and -IIA.	Nitrogen	56-57	phospholipase A2 group X	Homo sapiens	34-43
10567392-9	1999	These results indicate that human sPLA(2)-X is a unique N-glycosylated sPLA(2) that releases arachidonic acid from human myeloid leukemia cells more efficiently than sPLA(2)-IB and -IIA.	Nitrogen	56-57	phospholipase A2 group X	Homo sapiens	166-185
10690315-6	1999	The maximum conductance of ICa,L was increased by 10 microM insulin from 4.0 +/- 0.3 nS to 8.3 +/- 1.0 nS (n = 6).	Nitrogen	85-87	insulin	Homo sapiens	60-67
10558878-3	1999	The full-length cDNA for rat DLAD cloned by polymerase chain reaction encodes a 356-amino acid polypeptide containing a putative N-terminal signal peptide and 5 potential N-glycosylation sites; there is a predicted catalytic domain resemblance to rat DNase II.	Nitrogen	18-19	deoxyribonuclease 2 beta	Rattus norvegicus	29-33
10551860-10	1999	The HelB mutant retained about 20% of the cyclooxygenase activity of native oPGHS-1 and partitioned in subcellular fractions like native oPGHS-1; however, the HelB mutant exhibited an extra site of N-glycosylation at Asn(104).	Nitrogen	198-199	DNA helicase B	Homo sapiens	4-8
10551860-10	1999	The HelB mutant retained about 20% of the cyclooxygenase activity of native oPGHS-1 and partitioned in subcellular fractions like native oPGHS-1; however, the HelB mutant exhibited an extra site of N-glycosylation at Asn(104).	Nitrogen	198-199	DNA helicase B	Homo sapiens	159-163
10647012-8	1999	NIN protein has regional similarity to transcription factors, and the predicted DNA-binding/dimerization domain identifies and typifies a consensus motif conserved in plant proteins with a function in nitrogen-controlled development.	Nitrogen	201-209	nin	Lotus japonicus	0-3
10513988-6	1999	Analogs containing a quaternary nitrogen stimulated Pgp ATPase activity with lesser efficacy, while Ka values were somewhat higher when compared to corresponding tertiary analogs.	Nitrogen	32-40	ATP binding cassette subfamily B member 1	Homo sapiens	52-55
10528166-8	1999	Ly-49D-dependent recognition of Chinese hamster cells was independent of target N-linked glycosylation.	Nitrogen	80-81	killer cell lectin-like receptor, subfamily A, member 4	Mus musculus	0-6
10534316-12	1999	Taken together, the results indicated that CYP3A7 was the major if not sole isoform responsible for catalysis of the N-demethylation of imipramine in human hepatic tissues during embryogenesis.	Nitrogen	117-118	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	43-49
10559172-1	1999	Dal82p binds to the UIS(ALL) sites of allophanate-induced genes of the allantoin-degradative pathway and functions synergistically with the GATA family Gln3p and Gat1p transcriptional activators that are responsible for nitrogen catabolite repression-sensitive gene expression.	Nitrogen	220-228	Dal82p	Saccharomyces cerevisiae S288C	0-6
10539774-5	1999	True oro-ileal digestibility of SPI nitrogen was 91%.	Nitrogen	36-44	chromogranin A	Homo sapiens	32-35
10514491-4	1999	Diploid cells lacking Gpr1p, Plc1p, or Gpa2p fail to form pseudohyphae upon nitrogen depletion, and the filamentation defect of gpr1Delta and plc1Delta strains is rescued by activating a mitogen-activated protein kinase pathway via STE11-4 or by activating a cAMP pathway via overexpressed Tpk2p.	Nitrogen	76-84	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	39-44
10964007-1	1999	Mechanism-based inactivation of selected cytochrome P450 (CYP) isozymes by xenobiotics can lead to N-alkylation of the heme moiety and the formation of ferrochelatase-inhibitory N-alkylprotoporphyrin IX (N-alkylPP), resulting in hepatic porphyrin accumulation and porphyria.	Nitrogen	99-100	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	41-56
10964007-1	1999	Mechanism-based inactivation of selected cytochrome P450 (CYP) isozymes by xenobiotics can lead to N-alkylation of the heme moiety and the formation of ferrochelatase-inhibitory N-alkylprotoporphyrin IX (N-alkylPP), resulting in hepatic porphyrin accumulation and porphyria.	Nitrogen	99-100	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	58-61
10964007-6	1999	It was concluded that microsomal preparations containing cDNA-expressed CYP isozymes do not contain sufficient CYP for in vitro studies designed to isolate N-alkylPP and human liver microsomes would be a more appropriate source of N-alkylPP because they contain higher levels of total CYP.	Nitrogen	59-60	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	72-75
10645729-4	1999	ARS levels were very low in cells grown in the presence of NH4Cl and dramatically increased on agar medium deprived of any nitrogen source or containing nitrate, nitrite, urea, arginine or glutamine.	Nitrogen	123-131	uncharacterized protein	Chlamydomonas reinhardtii	0-3
10571453-1	1999	BACKGROUND: Administration of growth factors such as growth hormone (GH) and insulin-like growth factor-I (IGF-I) is being investigated as a strategy to promote nitrogen accretion in catabolic patients who may require total parenteral nutrition (TPN).	Nitrogen	161-169	growth hormone 1	Homo sapiens	53-67
10571453-1	1999	BACKGROUND: Administration of growth factors such as growth hormone (GH) and insulin-like growth factor-I (IGF-I) is being investigated as a strategy to promote nitrogen accretion in catabolic patients who may require total parenteral nutrition (TPN).	Nitrogen	161-169	growth hormone 1	Homo sapiens	69-71
10571453-1	1999	BACKGROUND: Administration of growth factors such as growth hormone (GH) and insulin-like growth factor-I (IGF-I) is being investigated as a strategy to promote nitrogen accretion in catabolic patients who may require total parenteral nutrition (TPN).	Nitrogen	161-169	insulin like growth factor 1	Homo sapiens	77-105
10571453-1	1999	BACKGROUND: Administration of growth factors such as growth hormone (GH) and insulin-like growth factor-I (IGF-I) is being investigated as a strategy to promote nitrogen accretion in catabolic patients who may require total parenteral nutrition (TPN).	Nitrogen	161-169	insulin like growth factor 1	Homo sapiens	107-112
10571453-9	1999	CONCLUSIONS: Simultaneous treatment with GH and IGF-I may offer the greatest clinical efficacy because of improved nitrogen retention in association with enhanced lipid oxidation and stimulation of protein synthesis in multiple tissue types.	Nitrogen	115-123	growth hormone 1	Homo sapiens	41-43
10571453-9	1999	CONCLUSIONS: Simultaneous treatment with GH and IGF-I may offer the greatest clinical efficacy because of improved nitrogen retention in association with enhanced lipid oxidation and stimulation of protein synthesis in multiple tissue types.	Nitrogen	115-123	insulin like growth factor 1	Homo sapiens	48-53
10592028-0	1999	Expression of a conifer glutamine synthetase gene in transgenic poplar The assimilation of ammonium into organic nitrogen catalyzed by the enzyme glutamine synthetase (GS; EC 6.3.1.2) has been suggested to be the limiting step for plant nitrogen utilization (H-M. Lam et al.	Nitrogen	113-121	glutamate-ammonia ligase	Homo sapiens	24-44
10592028-0	1999	Expression of a conifer glutamine synthetase gene in transgenic poplar The assimilation of ammonium into organic nitrogen catalyzed by the enzyme glutamine synthetase (GS; EC 6.3.1.2) has been suggested to be the limiting step for plant nitrogen utilization (H-M. Lam et al.	Nitrogen	113-121	glutamate-ammonia ligase	Homo sapiens	146-166
10592028-0	1999	Expression of a conifer glutamine synthetase gene in transgenic poplar The assimilation of ammonium into organic nitrogen catalyzed by the enzyme glutamine synthetase (GS; EC 6.3.1.2) has been suggested to be the limiting step for plant nitrogen utilization (H-M. Lam et al.	Nitrogen	237-245	glutamate-ammonia ligase	Homo sapiens	24-44
10592028-0	1999	Expression of a conifer glutamine synthetase gene in transgenic poplar The assimilation of ammonium into organic nitrogen catalyzed by the enzyme glutamine synthetase (GS; EC 6.3.1.2) has been suggested to be the limiting step for plant nitrogen utilization (H-M. Lam et al.	Nitrogen	237-245	glutamate-ammonia ligase	Homo sapiens	146-166
10574586-0	1999	N-glycosylation contributes to the intracellular stability of prothrombin precursors in the endoplasmic reticulum.	Nitrogen	0-1	coagulation factor II, thrombin	Homo sapiens	62-73
10574586-2	1999	The role of N-glycosylation in the cellular processing of prothrombin was examined in hepatoma (H-35 and HepG2) and transformed kidney (HEK293) cell lines.	Nitrogen	12-13	coagulation factor II, thrombin	Homo sapiens	58-69
10521251-6	1999	For the Fe(III)-substituted insulin hexamer, appearance of (1)H NMR R-state signatures requires, additionally to phenol, ligands containing a nitrogen that can donate a lone pair of electrons.	Nitrogen	142-150	insulin	Homo sapiens	28-35
10506174-5	1999	rom/D2 was N-glycosylated, formed covalent homodimers, and interacted non-covalently with itself, rds, and rom1.	Nitrogen	11-12	peripherin 2	Mus musculus	98-101
10511541-8	1999	These results suggest that Mks1p is involved in nitrogen control upstream of Ure2p as follows: NH(3) dash, vertical Mks1p dash, vertical Ure2p dash, vertical Gln3p --&gt; DAL5.	Nitrogen	48-56	glutathione peroxidase	Saccharomyces cerevisiae S288C	77-82
10516271-8	1999	Hepatic Gln metabolism via the PDG pathway has a central role in ureagenesis via 1) supplementation of nitrogen for the synthesis of carbamyl phosphate, and 2) providing glutamate for N-acetylglutamate synthesis.	Nitrogen	103-111	glutaminase 2	Homo sapiens	31-34
10760842-0	1999	Enzymes in addition to CYP3A4 and 3A5 mediate N-demethylation of dextromethorphan in human liver microsomes.	Nitrogen	46-47	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	23-29
10504408-4	1999	The membrane-bound and soluble forms of PC-1 were indistinguishable from each other in terms of their enzyme kinetics and N-glycosylated moieties.	Nitrogen	122-123	ectonucleotide pyrophosphatase/phosphodiesterase 1	Homo sapiens	40-44
10511541-0	1999	Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae.	Nitrogen	24-32	glutathione peroxidase	Saccharomyces cerevisiae S288C	56-61
10512868-8	1999	Mutants expressing a nonphosphorylatable mutant Cdc28 or deficient for Swe1 exhibit low-nitrogen-dependent filamentous growth and are further induced by an ectopic MAPK signal.	Nitrogen	88-96	tyrosine protein kinase SWE1	Saccharomyces cerevisiae S288C	71-75
10511541-2	1999	Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation.	Nitrogen	61-69	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
10511541-2	1999	Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation.	Nitrogen	151-159	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
10496963-1	1999	The presence of a nitrogen atom, charged at physiological pH, has frequently been considered to be a hallmark of P-glycoprotein (PGP) inhibitors, although certain steroids, such as progesterone, lack a nitrogen atom and still are active modulators of PGP.	Nitrogen	18-26	ATP binding cassette subfamily B member 1	Homo sapiens	113-127
10496963-1	1999	The presence of a nitrogen atom, charged at physiological pH, has frequently been considered to be a hallmark of P-glycoprotein (PGP) inhibitors, although certain steroids, such as progesterone, lack a nitrogen atom and still are active modulators of PGP.	Nitrogen	18-26	ATP binding cassette subfamily B member 1	Homo sapiens	129-132
10488137-5	1999	To further characterize the membrane topology and targeting of this protein, an N-glycosylation site was engineered into mEH to serve as a topological probe for the elucidation of the cellular location of mEH domains.	Nitrogen	80-81	epoxide hydrolase 1, microsomal	Mus musculus	121-124
10496963-1	1999	The presence of a nitrogen atom, charged at physiological pH, has frequently been considered to be a hallmark of P-glycoprotein (PGP) inhibitors, although certain steroids, such as progesterone, lack a nitrogen atom and still are active modulators of PGP.	Nitrogen	18-26	ATP binding cassette subfamily B member 1	Homo sapiens	251-254
10496963-2	1999	The present study was aimed at investigating the role the nitrogen atom plays in the activity of PGP inhibitors.	Nitrogen	58-66	ATP binding cassette subfamily B member 1	Homo sapiens	97-100
10496963-6	1999	The interaction of the nitrogen atom with PGP therefore is nonional and is determined by the sum of the hydrogen acceptor strengths of the region.	Nitrogen	23-31	ATP binding cassette subfamily B member 1	Homo sapiens	42-45
10471642-1	1999	BACKGROUND: Chronic alcohol abuse alters the normal N-glycosylation of transferrin, producing the carbohydrate-deficient transferrin isoforms.	Nitrogen	8-9	transferrin	Homo sapiens	71-82
10491387-2	1999	One class, represented by the general amino acid permease GAP1, contains permeases regulated in response to the nitrogen source.	Nitrogen	112-120	amino acid permease GAP1	Saccharomyces cerevisiae S288C	58-62
10514258-6	1999	In our recent report, various immunoblotting analyses have shown that the presence of a core N-glycosylation resident in the hIL-1beta fragment is likely to be of crucial importance in the high-level secretion of hG-CSF from the recombinant S. cerevisiae.	Nitrogen	93-94	interleukin 1 beta	Homo sapiens	125-134
10471642-1	1999	BACKGROUND: Chronic alcohol abuse alters the normal N-glycosylation of transferrin, producing the carbohydrate-deficient transferrin isoforms.	Nitrogen	8-9	transferrin	Homo sapiens	121-132
10471642-5	1999	A specific antibody directed against the amino acid sequence surrounding the N-432 N-glycosylation site of transferrin was prepared (SZ-350 antibody).	Nitrogen	77-78	transferrin	Homo sapiens	107-118
10471642-5	1999	A specific antibody directed against the amino acid sequence surrounding the N-432 N-glycosylation site of transferrin was prepared (SZ-350 antibody).	Nitrogen	83-84	transferrin	Homo sapiens	107-118
10455149-4	1999	Enzymatic N-deglycosylation resulted in an Epo-Epo species that migrated on SDS-polyacrylamide gel electrophoresis as a narrow band with an average apparent molecular mass of 39 kDa.	Nitrogen	10-11	erythropoietin	Homo sapiens	43-46
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	128-134
10589376-7	1999	It is speculated that decreased anaplerotic carbon flux in the tricarboxylic acid cycle, as a consequence of insulin resistance, may have an important role in the down-regulation of transamination of leucine during pregnancy, and may contribute to the conservation and accretion of nitrogen by the mother and the fetus.	Nitrogen	282-290	insulin	Homo sapiens	109-116
10482305-2	1999	The biosynthesis of MPO is normally restricted to the promyelocytic stage of myeloid development and includes N-linked glycosylation, heme insertion, proteolytic processing, subunit dimerization, and eventual targeting to the azurophilic granule.	Nitrogen	110-111	myeloperoxidase	Homo sapiens	20-23
10454558-4	1999	Overexpression of Ime2p inhibits pseudohyphal development and enables diploid cells to sporulate even in the presence of glucose or nitrogen.	Nitrogen	132-140	protein kinase IME2	Saccharomyces cerevisiae S288C	18-23
10454558-6	1999	Furthermore, deletion of GPA2 accelerates sporulation on low-nitrogen medium.	Nitrogen	61-69	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	25-29
10454558-9	1999	Upon starvation, expression of Gpa2p and Ime2p is induced but sporulation is prevented as long as nitrogen is present in the medium.	Nitrogen	98-106	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	31-36
10454558-9	1999	Upon starvation, expression of Gpa2p and Ime2p is induced but sporulation is prevented as long as nitrogen is present in the medium.	Nitrogen	98-106	protein kinase IME2	Saccharomyces cerevisiae S288C	41-46
10455138-7	1999	Membrane-tethered PC1 and PC2 exhibited changes in pro-domain maturation rates, N-glycosylation, and in the pH and calcium optima required for maximal enzymatic activity against a fluorogenic substrate.	Nitrogen	80-81	proprotein convertase subtilisin/kexin type 2	Mus musculus	26-29
10455149-4	1999	Enzymatic N-deglycosylation resulted in an Epo-Epo species that migrated on SDS-polyacrylamide gel electrophoresis as a narrow band with an average apparent molecular mass of 39 kDa.	Nitrogen	10-11	erythropoietin	Homo sapiens	47-50
10438923-2	1999	Dad1 is also a subunit of the oligosaccharyltransferase enzyme complex that initiates N-linked glycosylation.	Nitrogen	86-87	defender against cell death 1	Mus musculus	0-4
10477832-3	1999	In the present study we have tested the effects of DuP-697 and NS-398 on the activity of PGHS-1 and further explored the interactions between these agents and the inhibition of PGHS-1 by aspirin, indomethacin and ibuprofen.	Nitrogen	63-65	prostaglandin-endoperoxide synthase 1	Homo sapiens	89-95
10477832-5	1999	The results show that DuP-697 and NS-398, at concentrations ranges which do not inhibit PGHS-1 activity, significantly attenuated the inhibition of PGHS-1 that was caused by aspirin and indomethacin.	Nitrogen	34-36	prostaglandin-endoperoxide synthase 1	Homo sapiens	148-154
10454632-8	1999	Measurements of repair rates of nitrogen mustard N-alkylpurine adducts in the highly transcribed RPB2 gene demonstrate defects in the processing of mono-adducts in rad4, rad14 and mag1 strains.	Nitrogen	32-40	DNA-directed RNA polymerase II core subunit RPB2	Saccharomyces cerevisiae S288C	97-101
10424762-7	1999	While the N-hydroxylation of the guanidine involves the usual monooxygenase activity of cytochrome P-450 (Clement et al., Biochem Pharmacol 46: 2249-2267, 1993), the resultant N-hydroxyguanidine decoupled the monooxygenase.	Nitrogen	10-11	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	88-104
10473105-4	1999	We now report that the DTIC N-demethylation involved in MTIC formation by human liver microsomes is catalyzed by CYP1A1, CYP1A2, and CYP2E1.	Nitrogen	28-29	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	133-139
10466817-7	1999	None of these UL10 gene products is modified by N- or O-linked glycosylation.	Nitrogen	0-1	envelope glycoprotein M	Gallid alphaherpesvirus 1	14-18
10443652-8	1999	The mean GH peak after GHRH+HEX in NS was 83.6+/-4.5 microg/L; the third and first percentile limits of the normal GH response were 55.5 and 51.2 microg/L, respectively).	Nitrogen	35-37	growth hormone releasing hormone	Homo sapiens	23-27
10421623-8	1999	These observations suggested that the N-demethylation of azelastine is most extensively catalyzed by the CYP2D6 and 3A4 isoforms in humans.	Nitrogen	38-39	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	105-111
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	109-113
10409731-5	1999	Mutations in these genes cause the nitrogen-regulated general amino acid permease gene (GAP1) to be abnormally expressed and block the nonspecific induction of arginase (CAR1) and the peptide transporter (PTR2).	Nitrogen	35-43	amino acid permease GAP1	Saccharomyces cerevisiae S288C	88-92
10419504-4	1999	Tunicamycin treatment resulted in a 140-kDa protein, the deduced size of NPC1, suggesting that NPC1 is N-glycosylated.	Nitrogen	73-74	NPC intracellular cholesterol transporter 1	Cricetulus griseus	95-99
10467005-4	1999	While Gap1p and Agp1p appear to be the main cysteine transporters on the non-repressing nitrogen source proline, Bap2p, Bap3p, Tat1p, Tat2p, Agp1p and Gnp1p are all important for cysteine uptake on ammonium-based medium.	Nitrogen	88-96	amino acid permease GAP1	Saccharomyces cerevisiae S288C	6-11
10405327-6	1999	In contrast to the previously published hMUC3 sequence, which terminates shortly after a single cysteine-rich EGF-like domain, conceptual protein translation of the dominant and largest PCR product identified two extracellular cysteine-rich EGF-like domains separated by an N-glycosylation-rich domain and a potential coiled-coil region, followed by a putative transmembrane region and a 75 amino acid cytoplasmic tail.	Nitrogen	274-275	MUC3	Homo sapiens	40-45
15304781-2	1999	At a constant nitrate loading rate (2500 mg NO3 --N/[L. d]), using acetate as organic electron donor and at a C/NO3 --N/ ratio of 1.23, an increase in the N2 production rate was observed when the ammonium loading rate was increased (25, 250, and 500 mg NH4 +-N/[L. d]).	Nitrogen	155-157	NBL1, DAN family BMP antagonist	Homo sapiens	44-47
15304781-2	1999	At a constant nitrate loading rate (2500 mg NO3 --N/[L. d]), using acetate as organic electron donor and at a C/NO3 --N/ ratio of 1.23, an increase in the N2 production rate was observed when the ammonium loading rate was increased (25, 250, and 500 mg NH4 +-N/[L. d]).	Nitrogen	155-157	NBL1, DAN family BMP antagonist	Homo sapiens	112-115
15304781-5	1999	At constant NH4 +-N/NO3 --N/ and C/NO3 --N/ ratios of 0.2 and 1.63, respectively, the molecular nitrogen production rate was increased at 300 and 500 mg NH4 +-N/(L. d), whereas at 200 mg NH4 +- N/(L. d) DNRA took place probably owing to culture conditions of low reductive power.	Nitrogen	96-104	NBL1, DAN family BMP antagonist	Homo sapiens	20-23
15304781-5	1999	At constant NH4 +-N/NO3 --N/ and C/NO3 --N/ ratios of 0.2 and 1.63, respectively, the molecular nitrogen production rate was increased at 300 and 500 mg NH4 +-N/(L. d), whereas at 200 mg NH4 +- N/(L. d) DNRA took place probably owing to culture conditions of low reductive power.	Nitrogen	96-104	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
10398706-0	1999	Simultaneous expression of NAD-dependent isocitrate dehydrogenase and other krebs cycle genes after nitrate resupply to short-term nitrogen-starved tobacco Mitochondrial NAD-dependent (IDH) and cytosolic NADP-dependent isocitrate dehydrogenases have been considered as candidates for the production of 2-oxoglutarate required by the glutamine synthetase/glutamate synthase cycle.	Nitrogen	131-139	isocitrate dehydrogenase [NADP]	Nicotiana tabacum	186-189
10362842-4	1999	N-Sulfated heparan sulfate decasaccharides depleted of FGF-1 binding domains showed dose-dependent and saturable binding to FGF-2.	Nitrogen	0-1	fibroblast growth factor 1	Homo sapiens	55-60
10362842-4	1999	N-Sulfated heparan sulfate decasaccharides depleted of FGF-1 binding domains showed dose-dependent and saturable binding to FGF-2.	Nitrogen	0-1	fibroblast growth factor 2	Homo sapiens	124-129
10362843-3	1999	Mutagenesis of asparagine 22 to glutamine abolished N-linked glycosylation of the V2 receptor (N22Q-V2R), without altering its function or level of expression.	Nitrogen	52-53	arginine vasopressin receptor 2	Homo sapiens	100-103
10362843-11	1999	The wild type V2R expressed in HEK 293, COS, or MDCK cells underwent N- and O-linked glycosylation.	Nitrogen	69-70	arginine vasopressin receptor 2	Homo sapiens	14-17
10362844-6	1999	Rate-zonal centrifugation and agarose electrophoretic analysis of the low-density fraction indicated that the N-glycosylated MUC2 polypeptide was present as putative monomer and dimer/oligomer species.	Nitrogen	110-111	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	125-129
10429212-1	1999	We have used the natural N-glycosylation site in the N-tail of cig30, a eukaryotic polytopic membrane protein, as a marker for N-tail translocation across the microsomal membrane.	Nitrogen	25-26	ELOVL fatty acid elongase 3	Homo sapiens	63-68
10398706-0	1999	Simultaneous expression of NAD-dependent isocitrate dehydrogenase and other krebs cycle genes after nitrate resupply to short-term nitrogen-starved tobacco Mitochondrial NAD-dependent (IDH) and cytosolic NADP-dependent isocitrate dehydrogenases have been considered as candidates for the production of 2-oxoglutarate required by the glutamine synthetase/glutamate synthase cycle.	Nitrogen	131-139	glutamine synthetase	Nicotiana tabacum	334-354
10387077-6	1999	The putative binding site for cTnI(33-80) was determined by mapping amide proton and nitrogen chemical shift changes, induced by the binding of cTnI(33-80), onto the C-terminal cTnC structure.	Nitrogen	85-93	troponin C1, slow skeletal and cardiac type	Homo sapiens	177-181
18967601-4	1999	The detection limit was 0.5 ppb for nitrogen dioxide with a sampling time of 8 min and a flow rate of 60 ml min(-1).	Nitrogen	36-44	CD59 molecule (CD59 blood group)	Homo sapiens	108-114
10381774-2	1999	PhIP is bioactivated by cytochrome P-450 enzymes to N-hydroxylated metabolites that undergo further activation by conjugation enzymes, including the N-acetyltransferases, NAT1 and NAT2.	Nitrogen	52-53	N-acetyltransferase 2 (arylamine N-acetyltransferase)	Mus musculus	180-184
10364189-1	1999	The serotonin transporter (SERT) is an N-glycosylated integral membrane protein that is predicted to contain 12 transmembrane regions.	Nitrogen	39-40	solute carrier family 6 member 4	Homo sapiens	4-25
10364189-1	1999	The serotonin transporter (SERT) is an N-glycosylated integral membrane protein that is predicted to contain 12 transmembrane regions.	Nitrogen	39-40	solute carrier family 6 member 4	Homo sapiens	27-31
10336628-26	1999	The Ks of plant CYP51 for LAB170250F (0.29 microM) and gamma-ketotriazole (0.40 microM) calculated from the type-II sp2 nitrogen-binding spectra were in better agreement with their reported effects as plant CYP51 inhibitors than values previously determined with plant microsomes.	Nitrogen	120-128	sterol 14-demethylase	Saccharomyces cerevisiae S288C	16-21
10397812-2	1999	Detailed analysis of the N-glycosylation of recombinant human IFN-gamma by matrix-assisted laser-desorption mass spectrometry showed that the protein secreted by Chinese hamster ovary and baculovirus-infected insect Sf9 cells was associated with complex sialylated or truncated tri-mannosyl core glycans, respectively.	Nitrogen	25-26	interferon gamma	Homo sapiens	62-71
10408227-9	1999	These results suggest that CYP enzyme(s) are mainly responsible for DMI formation at pH 8.5 and 7.5, and FMO enzyme(s) also are involved in IMI N-demethylation at a higher pH range in rat liver microsomes, at least in part.	Nitrogen	144-145	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	27-30
10411623-0	1999	Site-directed removal of N-glycosylation sites in human gastric lipase.	Nitrogen	25-26	lipase F, gastric type	Homo sapiens	56-70
10411623-2	1999	Four potential N-glycosylation consensus sites (Asn15, 80, 252 and 308) can be identified from the HGL amino acid sequence.	Nitrogen	15-16	lipase F, gastric type	Homo sapiens	99-102
10411623-10	1999	The N-glycosylation of HGL may contribute to the enzyme stability in the stomach, as under acidic conditions the degradation by pepsin of the unglycosylated r-HGL is increased.	Nitrogen	4-5	lipase F, gastric type	Homo sapiens	23-26
10411623-10	1999	The N-glycosylation of HGL may contribute to the enzyme stability in the stomach, as under acidic conditions the degradation by pepsin of the unglycosylated r-HGL is increased.	Nitrogen	4-5	lipase F, gastric type	Homo sapiens	159-162
10336989-6	1999	Following addition of dolichyl phosphate to MDA231 cells, N-linked glycosylation of IGF-1R was drastically increased, which in turn was correlated to a substantial translocation of IGF-1R to the plasma membrane, as assayed by IGF-1 binding analysis and by Western blotting of plasma membrane proteins.	Nitrogen	58-59	insulin like growth factor 1	Homo sapiens	84-89
10336628-26	1999	The Ks of plant CYP51 for LAB170250F (0.29 microM) and gamma-ketotriazole (0.40 microM) calculated from the type-II sp2 nitrogen-binding spectra were in better agreement with their reported effects as plant CYP51 inhibitors than values previously determined with plant microsomes.	Nitrogen	120-128	sterol 14-demethylase	Saccharomyces cerevisiae S288C	207-212
10381152-7	1999	GH decreased urinary nitrogen excretion, resulting in a cumulative nitrogen retention of 2,404 mmol, thereby correcting the acidosis-induced cumulative increase in nitrogen excretion (2,506 mmol) despite continued acid feeding.	Nitrogen	21-29	growth hormone 1	Homo sapiens	0-2
10330190-1	1999	Ure2p of Saccharomyces cerevisiae normally functions in blocking utilization of a poor nitrogen source when a good nitrogen source is available.	Nitrogen	87-95	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
10330190-1	1999	Ure2p of Saccharomyces cerevisiae normally functions in blocking utilization of a poor nitrogen source when a good nitrogen source is available.	Nitrogen	115-123	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
10381152-7	1999	GH decreased urinary nitrogen excretion, resulting in a cumulative nitrogen retention of 2,404 mmol, thereby correcting the acidosis-induced cumulative increase in nitrogen excretion (2,506 mmol) despite continued acid feeding.	Nitrogen	67-75	growth hormone 1	Homo sapiens	0-2
10381152-7	1999	GH decreased urinary nitrogen excretion, resulting in a cumulative nitrogen retention of 2,404 mmol, thereby correcting the acidosis-induced cumulative increase in nitrogen excretion (2,506 mmol) despite continued acid feeding.	Nitrogen	67-75	growth hormone 1	Homo sapiens	0-2
10381152-12	1999	In conclusion, GH corrected acidosis-induced renal nitrogen wasting, which may be caused, at least in part, by decreased IGF-1 levels.	Nitrogen	51-59	growth hormone 1	Homo sapiens	15-17
10198439-3	1999	In this report, we demonstrate that transient nitrogen limitation also causes INO1 repression.	Nitrogen	46-54	inositol-3-phosphate synthase INO1	Saccharomyces cerevisiae S288C	78-82
10417701-5	1999	However, Nrt1 is over-expressed in the NR mutant even under N-sufficient conditions (growth on NH4NO3 medium), suggesting that expression of this gene is affected by the presence of active NR, but not by N-status of the plant.	Nitrogen	9-10	nitrate reductase 1	Arabidopsis thaliana	39-41
10417701-5	1999	However, Nrt1 is over-expressed in the NR mutant even under N-sufficient conditions (growth on NH4NO3 medium), suggesting that expression of this gene is affected by the presence of active NR, but not by N-status of the plant.	Nitrogen	9-10	nitrate reductase 1	Arabidopsis thaliana	189-191
10223943-9	1999	We conclude that (i) the control exerted by gamma interferon on intracellular multiplication of Listeria in THP-1 macrophages is dependent on the production of nitric oxide and hydrogen peroxide; (ii) intracellular Listeria may become insensitive to ampicillin in macrophages exposed to gamma interferon because the increase in reactive oxygen and nitrogen intermediates already controls bacterial growth; and (iii) azithromycin and still more sparfloxacin cooperate efficiently with gamma interferon, one of the main cellular host defenses in Listeria infection.	Nitrogen	348-356	GLI family zinc finger 2	Homo sapiens	108-113
10340394-4	1999	When maintained in IL-3, about 3% of N-Fms cells formed large hemoglobinized colonies in semisolid cultures supplemented with erythropoietin (EPO).	Nitrogen	37-38	interleukin 3	Mus musculus	19-23
10194416-1	1999	Addition of ammonium ions to yeast cells growing on proline as the sole nitrogen source induces internalization of the general amino acid permease Gap1p and its subsequent degradation in the vacuole.	Nitrogen	72-80	amino acid permease GAP1	Saccharomyces cerevisiae S288C	147-152
10424353-2	1999	N-acylation of the synthetic peptide substrate NH2-Glu-Phe-Leu-Tyr-Gly-Val-Phe-Asp-CONH2 (EFLYGVFD) resulted in synergistic inhibition of Src protein kinase activity that was greater than the inhibition by either free peptide and/or free acyl group.	Nitrogen	0-1	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	138-141
10222064-9	1999	Taken together, these data suggested that IL-4-mediated inhibition of TNFalpha-induced monocyte HA binding was dependent not only on protein synthesis, but also on N-linked glycosylation and chondroitin-sulfate modification of either CD44 or, alternatively, another monocyte protein(s) that may regulate the ability of CD44 to bind HA.	Nitrogen	71-72	interleukin 4	Homo sapiens	42-46
10338219-1	1999	BACKGROUND: Recombinant human growth hormone (rhGH) has been shown to have powerful anabolic effects and to reduce or even prevent nitrogen catabolism in stressed patients.	Nitrogen	131-139	growth hormone 1	Homo sapiens	30-44
10198439-4	1999	The repression of INO1 in response to nitrogen limitation shares many features in common with repression in response to the presence of inositol.	Nitrogen	38-46	inositol-3-phosphate synthase INO1	Saccharomyces cerevisiae S288C	18-22
10198439-5	1999	Specifically, the response to nitrogen limitation is dependent upon the presence of a functional OPI1 gene product, it requires ongoing phosphatidylcholine biosynthesis and it is mediated by the repeated element, UASINO, found in the promoter of INO1 and other co-regulated genes of phospholipid biosynthesis.	Nitrogen	30-38	inositol-3-phosphate synthase INO1	Saccharomyces cerevisiae S288C	246-250
10329352-1	1999	Reactive oxygen and nitrogen intermediates (ROI, RNI), such as superoxide anion, nitric oxide (NO) and peroxynitrite, are present in villous trophoblasts and mediate TNF-alpha-induced apoptosis in other cell types.	Nitrogen	20-28	tumor necrosis factor	Homo sapiens	166-175
10198439-6	1999	Thus, we propose that repression of INO1 in response to inositol and in response to nitrogen limitation occurs via a common mechanism that is sensitive to the status of ongoing phospholipid metabolism.	Nitrogen	84-92	inositol-3-phosphate synthase INO1	Saccharomyces cerevisiae S288C	36-40
10338138-1	1999	An oligopeptide containing three consecutive Thr residues mimicking the tandem repeat portion of MUC2 (PTTTPLK) was investigated for the acceptor specificity to UDP-N-acetyl-D-galactosamine:peptide N-acetylgalactosaminyltransferase isozymes, UDP-N-acetyl-D-galactosamine:peptide N-acetylgalactosaminyltransferase-T1, T2 and T3.	Nitrogen	165-167	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	97-101
10086330-4	1999	IL-2 was infused from day 7 to day 3 before hepatectomy and the conservation of a non-tumorous liver fragment in liquid nitrogen.	Nitrogen	120-128	interleukin 2	Homo sapiens	0-4
10229094-6	1999	Treatment with brefeldin A or with inhibitors of N-linked glycosylation further indicated that the 48L IL-15/GFP is secreted through the endoplasmic reticulum/Golgi pathway.	Nitrogen	49-50	interleukin-15	Cricetulus griseus	103-108
10385214-8	1999	In microsomes from 12 livers from man the rate of N-debutylation of halofantrine correlated strongly with CYP 3A4 relative levels (P = 0.002) and less strongly, but significantly, with CYP 2C8 levels (P = 0.025).	Nitrogen	50-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	106-109
10187864-4	1999	Hydrophobicity analysis of the KCC3 amino acid sequence showed an almost identical pattern to KCC1, suggesting 12 membrane-spanning segments, a large extracellular loop with potential N-glycosylation sites, and cytoplasmic N- and C-terminal regions.	Nitrogen	184-185	solute carrier family 12 member 6	Homo sapiens	31-35
10233205-11	1999	CONCLUSIONS: The N-demethylation of methadone in human liver microsomes is not markedly stereoselective, and is mediated mainly by CYP3A4 with the possible involvement of CYP2C9 and CYP2C19.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	131-137
10359460-8	1999	This apparent involvement of CYP2D6 in the N-demethylation of CLZ did not corroborate with the findings of other experiments.	Nitrogen	43-44	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	29-35
10359460-9	1999	In conclusion, these data indicate that while both CYP isoforms readily catalyze both metabolic routes in vitro, CYP1A2 and CYP3A4 are more important in N-demethylation and N-oxidation, respectively.	Nitrogen	153-154	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	124-130
10101149-0	1999	Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes.	Nitrogen	42-43	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	19-25
10191360-3	1999	We find that in brain Kv1.1, Kv1.2 and Kv1.4, which have a single consensus glycosylation site in the first extracellular interhelical domain, are N-glycosylated with sialic acid-rich oligosaccharide chains.	Nitrogen	147-148	potassium voltage-gated channel subfamily A member 2	Homo sapiens	29-34
10191360-6	1999	The extent of processing of N-linked chains on Kv1.1 and Kv1.2 but not Kv1.4 channels expressed in transfected cells differs from that seen for native brain channels, reflecting the different efficiencies of transport of K+ channel polypeptides from the endoplasmic reticulum to the Golgi apparatus.	Nitrogen	28-29	potassium voltage-gated channel subfamily A member 2	Homo sapiens	57-62
10419027-8	1999	The mutated SHBG is characterized by a point mutation (Asp 327 --&gt; Asn) causing an additional N-glycosylation site, which does not affect the binding of steroids to SHBG.	Nitrogen	97-98	sex hormone binding globulin	Homo sapiens	12-16
10211818-5	1999	In the mutant Thr93Gln, the Gln93N epsilon2 nitrogen replaces WAT1 and participates in a similar hydrogen bond network involving Cys6, Asn9, Asp76, and Thr91.	Nitrogen	44-52	MTOR associated protein, LST8 homolog	Homo sapiens	62-66
10085102-9	1999	The predicted amino acid sequence showed 78% identity to human tapasin with identical consensus sequences of signal peptide, N-linked glycosylation site, transmembrane domain and double lysine motif.	Nitrogen	125-126	TAP binding protein	Homo sapiens	63-70
10341444-4	1999	Here, this observation is confirmed and extended by showing that non-viral expression of a 50 kDa TMV helicase fragment (p50) is sufficient to induce the N-mediated HR in tobacco.	Nitrogen	154-155	nuclear factor kappa B subunit 1	Homo sapiens	121-124
11670899-5	1999	2, C(17)H(16)N(4)Cl(2)Cu: a = 7.6659(7) A, b = 16.287(1) A, c = 14.103(1) A, beta = 95.058(7) degrees, monoclinic, P2(1)/c, and Z = 4.	Nitrogen	13-14	cyclin dependent kinase inhibitor 1A	Homo sapiens	115-122
10090785-4	1999	Replacement of the oxygen in the chromenone ring of 6 by a nitrogen atom further improved the inhibitory activity against the EGFR kinase.	Nitrogen	59-67	epidermal growth factor receptor	Homo sapiens	126-130
10064623-5	1999	Here we report that the stable carbon and nitrogen isotope values for the hair of the 5200 year-old Ice Man indicates a primarily vegetarian diet, in agreement with his dental wear pattern.	Nitrogen	42-50	carboxylesterase 2	Homo sapiens	100-103
10424400-3	1999	A variant SHBG with a point mutation in exon 8, causing an aminoacid substitution (Asp 327-->Asn) and thus, the introduction of an additional N-glycosylation site, has been reported.	Nitrogen	142-143	sex hormone binding globulin	Homo sapiens	10-14
10064623-0	1999	The Ice Man"s diet as reflected by the stable nitrogen and carbon isotopic composition of his hair.	Nitrogen	46-54	carboxylesterase 2	Homo sapiens	4-7
10066782-0	1999	Disulfide bond structure and N-glycosylation sites of the extracellular domain of the human interleukin-6 receptor.	Nitrogen	29-30	interleukin 6 receptor	Homo sapiens	92-114
21662775-6	1999	The detection limit for S/N = 3 is 0.1 muM.	Nitrogen	26-27	latexin	Homo sapiens	39-42
10219963-18	1999	These results suggest that both the N-demethylation and S-oxidation of zotepine are mediated mainly by CYP3A4, and that CYP1A2 and 2D6 play an important role in the 2- and 3-hydroxylation of zotepine, respectively.	Nitrogen	36-37	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	103-109
10024680-5	1999	Particular emphasis has been given to tumour necrosis factor-alpha (TNF-alpha) which seems to have a key role in mediating changes related to nitrogen metabolism in the tumour-bearing host.	Nitrogen	142-150	tumor necrosis factor	Homo sapiens	68-77
10205909-6	1999	The use of inhibitors of N assimilation indicated that downregulation of Nrt2;1At expression was mediated by NH4+, gln and other amino acids.	Nitrogen	25-26	nitrate transporter 2:1	Arabidopsis thaliana	73-77
10344569-0	1999	First total synthesis of N-4909 and its diastereomer; a stimulant of apolipoprotein E secretion in human hepatoma Hep G2 cells.	Nitrogen	25-26	apolipoprotein E	Homo sapiens	69-85
9990015-3	1999	Exposure of preadipocytes to the calpain inhibitor N-acetyl-Leu-Leu-norleucinal or overexpression of calpastatin, a specific endogenous inhibitor of calpain, blocks expression of adipocyte-specific genes, notably the CCAAT/enhancer-binding protein (C/EBP)alpha gene, and acquisition of the adipocyte phenotype.	Nitrogen	51-52	CCAAT enhancer binding protein alpha	Homo sapiens	249-260
9931257-7	1999	The C-terminal carboxylate group of angiotensin I docked into the active-site cleft, with the last two residues extending beyond the active site, is perfectly localized to make a favorable hydrogen bond and salt bridge with the amide nitrogen of the Lys40-Phe41 peptide bond and with the epsilon-ammonium group of the Lys40 side-chain.	Nitrogen	234-242	angiotensinogen	Homo sapiens	36-49
10065739-12	1999	In summary, feeding mice a diet rich in n-3 PUFA from fish oil significantly lowered the production of both IL-12 and IFNgamma during the early phase of a Listeria infection.	Nitrogen	1-2	interferon gamma	Mus musculus	118-126
10219965-0	1999	Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21.	Nitrogen	45-46	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-15
10219965-2	1999	Cytochrome P450 (P450) isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate (NS-21) have been identified in rat and man.	Nitrogen	52-53	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-15
10219965-6	1999	Of several human recombinant P450 isoforms, CYP3A4 had the activities for the N-deethylation of S- and R-NS-21.	Nitrogen	78-79	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	44-50
10091584-2	1999	In pig, neutral complex-type N-linked chains obtained from a ZPB/ZPC mixture possess sperm-binding activity.	Nitrogen	29-30	zona pellucida glycoprotein 4	Sus scrofa	61-64
10091584-4	1999	Triantennary and tetraantennary chains are localized at the second of the three N-glycosylation sites of ZPB.	Nitrogen	80-81	zona pellucida glycoprotein 4	Sus scrofa	105-108
10202979-2	1999	Nitric oxide (NO) is an important synaptic plasticity molecule generated by nitric oxide synthase (NOS) oxidation of a guanidino nitrogen of L-arginine.	Nitrogen	129-137	nitric oxide synthase 2	Homo sapiens	76-97
9890751-7	1999	Computer analysis of the protein structure from Spam1 cDNA sequence reveals four putative N-linked glycosylation sites, and enzymatic deglycosylation suggests that all sites are functional.	Nitrogen	56-57	sperm adhesion molecule 1	Mus musculus	48-53
9973386-6	1999	To determine how env peptides are generated in the cytosol, we analyzed the processing of two TAP1/2-dependent epitopes containing N-linked glycosylation sites.	Nitrogen	131-132	transporter 1, ATP binding cassette subfamily B member	Homo sapiens	94-98
10048020-4	1999	Gan1p is required for full expression of GLN1, GDH2 and also other nitrogen utilization genes, including GAP1, PUT4, MEP2 and GDH1.	Nitrogen	67-75	amino acid permease GAP1	Saccharomyces cerevisiae S288C	105-109
10199594-4	1999	Among the hepatic P450s, the N-demethylation of aminopyrine was catalysed most efficiently by CYP2C19, followed by CYP2C8, 2D6, 2C18 and 1A2, whereas the activity with CYP2E1 was negligible.	Nitrogen	29-30	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	168-174
10199594-10	1999	Human steroidogenic CYP17 also catalysed aminopyrine N-demethylation and the activity was comparable with that for CYP3A4 which is a dominant P450 in human liver.	Nitrogen	53-54	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	115-121
10216911-5	1999	Possum ZP3 has a 46% amino acid identity with eutherian ZP3 and shares similar structural characteristics including 12 conserved cysteine residues, N-linked glycosylation sites and hydrophobic regions.	Nitrogen	148-149	zona pellucida sperm-binding protein 3	Oryctolagus cuniculus	7-10
9892660-0	1999	Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line.	Nitrogen	68-76	rhodopsin	Homo sapiens	80-89
9892660-6	1999	The 15N resonance corresponding to the protonated retinylidene Schiff base nitrogen was observed at 156.8 ppm in the MAS spectrum of 6-15N-lysine-labeled rhodopsin.	Nitrogen	75-83	rhodopsin	Homo sapiens	154-163
10695086-3	1999	It is recognised that the three features are interrelated, for example insulin is believed to be an important factor in controlling amino acid flux in skeletal muscle and increasing environmental temperature which may reduce flow phase hypermetabolism has been shown to reduce postoperative nitrogen excretion (a marker of protein catabolism).	Nitrogen	291-299	insulin	Homo sapiens	71-78
10234440-1	1999	The interaction of potential pesticides, O,O-dialkyl S-ethoxycarbonylbromomethylthiophosphates (RO)2P(O)SCH(Br)COOC2H5 (R = Et, i-Pr, n-Pr, n-Bu, n-Am, or n-Hx) with the esterases of warm-blooded animals [acetylcholinesterase (ACE), butyryl cholinesterase (BCE), and carboxyl esterase (CE)] was studied.	Nitrogen	5-6	butyrylcholinesterase	Mus musculus	233-255
10234440-1	1999	The interaction of potential pesticides, O,O-dialkyl S-ethoxycarbonylbromomethylthiophosphates (RO)2P(O)SCH(Br)COOC2H5 (R = Et, i-Pr, n-Pr, n-Bu, n-Am, or n-Hx) with the esterases of warm-blooded animals [acetylcholinesterase (ACE), butyryl cholinesterase (BCE), and carboxyl esterase (CE)] was studied.	Nitrogen	5-6	butyrylcholinesterase	Mus musculus	257-260
10447581-4	1999	Enzyme kinetic analyses revealed the dominant role of human CYP3A4 in 4-hydroxylation and N-dechloroethylation of trofosfamide.	Nitrogen	90-91	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	60-66
10493260-2	1999	Although CYP2D6 substrates are structurally diverse, most are small molecules that interact with the protein via an electrostatic interaction between a basic nitrogen which is common to the majority of CYP2D6 substrates and an aspartic acid residue in the active site of the protein.	Nitrogen	158-166	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	9-15
10352397-9	1999	By contrast, the GH group increased in lean body mass (1.13 +/- 1.04 kg) and had a positive nitrogen balance (1.81 +/- 2.06 g/day).	Nitrogen	92-100	growth hormone 1	Homo sapiens	17-19
10493260-2	1999	Although CYP2D6 substrates are structurally diverse, most are small molecules that interact with the protein via an electrostatic interaction between a basic nitrogen which is common to the majority of CYP2D6 substrates and an aspartic acid residue in the active site of the protein.	Nitrogen	158-166	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	202-208
9880100-5	1998	Four cysteine residues and two of four N-glycosylation sites that are conserved among species were also found at the corresponding positions in feline TPO.	Nitrogen	39-40	thrombopoietin	Homo sapiens	151-154
9866865-3	1998	Secretion of anchor-less SAG1 proceeded via the yeast prepro alpha-mating factor signal peptide and yielded two immunoreactive protein species having apparent molecular masses of 31.5 and 34.5 kDa, respectively, and differing only by N-glycosylation of the single Asn-X-Ser site present in the molecule.	Nitrogen	234-235	Sag1p	Saccharomyces cerevisiae S288C	25-29
10445051-3	1999	The mechanism of MAO-B inhibition is discussed in terms of the Ionization Potential of the amine nitrogen atom and the conformational flexibility of the inhibitors.	Nitrogen	97-105	monoamine oxidase B	Bos taurus	17-22
9886097-11	1999	These observations indicate that N-glycosylation of rds/peripherin is not required for its normal processing, stability, or in vivo function.	Nitrogen	33-34	peripherin 2	Mus musculus	52-66
9932682-10	1999	RESULTS: Postinjury PMNs were primed for both platelet-activating factor/N-formyl-methionyl-leucyl-phenylalanine-stimulated and lipopolysaccharide-stimulated IL-8 and TNF release at 2 hours after injury (fourfold increase of IL-8 release and fivefold increase of TNF release), whereas elective surgical patients demonstrated no priming.	Nitrogen	22-23	C-X-C motif chemokine ligand 8	Homo sapiens	158-162
9932682-10	1999	RESULTS: Postinjury PMNs were primed for both platelet-activating factor/N-formyl-methionyl-leucyl-phenylalanine-stimulated and lipopolysaccharide-stimulated IL-8 and TNF release at 2 hours after injury (fourfold increase of IL-8 release and fivefold increase of TNF release), whereas elective surgical patients demonstrated no priming.	Nitrogen	22-23	tumor necrosis factor	Homo sapiens	167-170
9932682-10	1999	RESULTS: Postinjury PMNs were primed for both platelet-activating factor/N-formyl-methionyl-leucyl-phenylalanine-stimulated and lipopolysaccharide-stimulated IL-8 and TNF release at 2 hours after injury (fourfold increase of IL-8 release and fivefold increase of TNF release), whereas elective surgical patients demonstrated no priming.	Nitrogen	22-23	C-X-C motif chemokine ligand 8	Homo sapiens	225-229
9932682-10	1999	RESULTS: Postinjury PMNs were primed for both platelet-activating factor/N-formyl-methionyl-leucyl-phenylalanine-stimulated and lipopolysaccharide-stimulated IL-8 and TNF release at 2 hours after injury (fourfold increase of IL-8 release and fivefold increase of TNF release), whereas elective surgical patients demonstrated no priming.	Nitrogen	22-23	tumor necrosis factor	Homo sapiens	263-266
10391466-10	1999	Inhibition of inducible nitric oxide synthase expression by N(G)-nitro-L-arginine methyl ester administration prevented the increase in nitrogen intermediates and GABA release, but not in glutamate release.	Nitrogen	136-144	nitric oxide synthase 2	Rattus norvegicus	14-45
9852116-7	1998	A disulfide bond between Cys18 and Cys138 using a fully N-deglycosylated mutant of human angiotensinogen was identified by tryptic digestion and mass spectrometry.	Nitrogen	56-57	angiotensinogen	Homo sapiens	89-104
9850065-13	1998	Incubations of NNK with COX-1 and -2 produced both activation and detoxification products by alpha-carbon hydroxylation and N-oxydation pathways, respectively.	Nitrogen	15-16	cytochrome c oxidase I, mitochondrial	Mus musculus	24-36
10099468-0	1998	Monitoring recombinant human interferon-gamma N-glycosylation during perfused fluidized-bed and stirred-tank batch culture of CHO cells.	Nitrogen	46-47	interferon gamma	Homo sapiens	29-45
9817938-1	1998	An osteocalcin (OC) nitrogen (N)-terminal sandwich enzyme immunoassay that employs anit-N-20 (amino acids 1-20) polyclonal and monoclonal antibodies has been developed.	Nitrogen	20-28	bone gamma-carboxyglutamate protein	Homo sapiens	3-14
9817938-1	1998	An osteocalcin (OC) nitrogen (N)-terminal sandwich enzyme immunoassay that employs anit-N-20 (amino acids 1-20) polyclonal and monoclonal antibodies has been developed.	Nitrogen	20-28	bone gamma-carboxyglutamate protein	Homo sapiens	16-18
9846860-9	1998	The weight and protein content of the diaphragm were lower and nitrogen excretion was higher in the TNF+Cort group than in the respective PF group.	Nitrogen	63-71	tumor necrosis factor	Rattus norvegicus	100-103
9832522-2	1998	Recognition of nitrogen starvation is mediated, at least in part, by the ammonium permease Mep2p and the Galpha subunit Gpa2p.	Nitrogen	15-23	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	120-125
9836512-5	1998	In addition, insulin also decreased (P &lt; 0.001) leucine nitrogen flux substantially more than leucine carbon flux, indicating increased leucine transamination (an important biochemical process for nitrogen transfer between amino acids and across the organs), in a dose-dependent manner, with the magnitude of effect being greater on skeletal muscle than on the splanchnic bed.	Nitrogen	59-67	insulin	Homo sapiens	13-20
9836512-5	1998	In addition, insulin also decreased (P &lt; 0.001) leucine nitrogen flux substantially more than leucine carbon flux, indicating increased leucine transamination (an important biochemical process for nitrogen transfer between amino acids and across the organs), in a dose-dependent manner, with the magnitude of effect being greater on skeletal muscle than on the splanchnic bed.	Nitrogen	200-208	insulin	Homo sapiens	13-20
9851979-3	1998	Suppressor of Hairless [Su(H)] is predominantly associated with soluble intracellular N.	Nitrogen	86-87	Suppressor of Hairless	Drosophila melanogaster	24-29
9804702-3	1998	Additional studies have shown that this class of NK1 antagonist tolerates a wider range of substituents on the piperidine nitrogen, including acyl (38) (hNK1 IC50 = 5.3 nM) and sulfonyl (39) (hNK1 IC50 = 5.7 nM) derivatives.	Nitrogen	122-130	beta-1,3-glucuronyltransferase 1	Homo sapiens	49-52
9834126-4	1998	M-CSF not only increased the levels of p26 HRF mRNA and protein, but also stimulated the secretion of an N-glycosylated p26 HRF with a m.w.	Nitrogen	49-50	transmembrane p24 trafficking protein 4	Mus musculus	39-42
9850741-2	1998	Nitric oxide synthase (NOS) is the enzyme that catalyzes the formation of nitric oxide (NO), a regulator of vascular permeability, from the guanidino nitrogen atom of L-arginine.	Nitrogen	150-158	nitric oxide synthase 2	Homo sapiens	0-21
10189263-8	1998	The current study was undertaken to confirm the putative involvement of CYP3A4 in the N-dealkylation of Hf to Hfm by administering Hf with and without ketoconazole (KC), a specific CYP3A4 inhibitor, and measuring the resulting plasma concentration profiles of Hf and Hfm.	Nitrogen	86-87	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	72-78
9804883-8	1998	Immunoblot analysis shows that R. capsulatus POR is constitutively synthesized, with synthesis augmented under nitrogen-fixing conditions (34+/-13%) and decreased in acetate and aerobically grown cells.	Nitrogen	111-119	cytochrome p450 oxidoreductase	Homo sapiens	45-48
29711098-1	1998	The high-pressure reaction of solid Ca3 N2 with gold in a nitrogen atomsphere affords the ternary auride nitride Ca2 AuN.	Nitrogen	58-66	carbonic anhydrase 3	Homo sapiens	36-39
9844122-11	1998	The production of TNF-alpha was inhibited by calcitriol in a dose-dependent manner [LPS + Vit.D3 100 ng, 2.9 +/- 2.1 in N, 3.7 +/- 1.9 in CRF and 3.4 +/- 1.7 in HD; LPS + Vit.D3 50 ng, 263 +/- 296 (N), 6.73 +/- 11 (CRF), 38 +/- 28 (HD); LPS + Vit.D3 25 ng = 873 +/- 583 (N), 325 +/- 483 (CRF), 588 +/- 507 (HD); LPS + Vit.D3 12.5 ng, 954 +/- 483 (N), 912 +/- 510 (CRF), 875 +/- 527 (HD)].	Nitrogen	19-20	vitrin	Homo sapiens	90-93
9839761-9	1998	Three metabolic pathways were identified: (i) O-dealkylation and hydroxylation to metabolites M1 and M2, with subsequent glucuronidation to metabolites M11 and M12; (ii) hydrolysis to metabolite M4; and (iii) N-oxidation to metabolite M6.	Nitrogen	209-210	myoregulin	Homo sapiens	94-103
9784538-4	1998	Kinetic studies after lipopolysaccharide stimulation show that NOS2 mRNA levels rise within 3 to 6 h, that conversion of [14C]arginine to [14C]citrulline is maximal at 5 to 6 days, and that levels of reactive nitrogen intermediates stabilize at around 20 microM at 7 to 8 days.	Nitrogen	209-217	nitric oxide synthase 2	Homo sapiens	63-67
9811645-2	1998	The DAS1 gene, encoding DHAS, was cloned from the host genome, and regulation of its expression by various carbon and nitrogen sources was analyzed.	Nitrogen	118-126	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	4-8
9811645-5	1998	The DAS1 gene was disrupted in one step in the host genome (das1Delta strain), and the growth of the das1Delta strain in various carbon and nitrogen sources was compared with that of the wild-type strain.	Nitrogen	140-148	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	4-8
9811645-8	1998	These and other experiments (e.g., those to determine the expression of the gene and the growth ability of the das1Delta strain on media containing methylamine or choline as a nitrogen source) suggested that DAS1 is involved in assimilation rather than dissimilation or detoxification of formaldehyde in the cells.	Nitrogen	176-184	SCF ubiquitin ligase complex subunit DAS1	Saccharomyces cerevisiae S288C	208-212
9751792-0	1998	Expression of N-linked sialyl Le(x) determinants and O-glycans in the carbohydrate moiety of human amniotic fluid transferrin during pregnancy.	Nitrogen	14-15	transferrin	Homo sapiens	114-125
9844122-11	1998	The production of TNF-alpha was inhibited by calcitriol in a dose-dependent manner [LPS + Vit.D3 100 ng, 2.9 +/- 2.1 in N, 3.7 +/- 1.9 in CRF and 3.4 +/- 1.7 in HD; LPS + Vit.D3 50 ng, 263 +/- 296 (N), 6.73 +/- 11 (CRF), 38 +/- 28 (HD); LPS + Vit.D3 25 ng = 873 +/- 583 (N), 325 +/- 483 (CRF), 588 +/- 507 (HD); LPS + Vit.D3 12.5 ng, 954 +/- 483 (N), 912 +/- 510 (CRF), 875 +/- 527 (HD)].	Nitrogen	19-20	vitrin	Homo sapiens	171-174
9844122-11	1998	The production of TNF-alpha was inhibited by calcitriol in a dose-dependent manner [LPS + Vit.D3 100 ng, 2.9 +/- 2.1 in N, 3.7 +/- 1.9 in CRF and 3.4 +/- 1.7 in HD; LPS + Vit.D3 50 ng, 263 +/- 296 (N), 6.73 +/- 11 (CRF), 38 +/- 28 (HD); LPS + Vit.D3 25 ng = 873 +/- 583 (N), 325 +/- 483 (CRF), 588 +/- 507 (HD); LPS + Vit.D3 12.5 ng, 954 +/- 483 (N), 912 +/- 510 (CRF), 875 +/- 527 (HD)].	Nitrogen	19-20	vitrin	Homo sapiens	171-174
9844122-11	1998	The production of TNF-alpha was inhibited by calcitriol in a dose-dependent manner [LPS + Vit.D3 100 ng, 2.9 +/- 2.1 in N, 3.7 +/- 1.9 in CRF and 3.4 +/- 1.7 in HD; LPS + Vit.D3 50 ng, 263 +/- 296 (N), 6.73 +/- 11 (CRF), 38 +/- 28 (HD); LPS + Vit.D3 25 ng = 873 +/- 583 (N), 325 +/- 483 (CRF), 588 +/- 507 (HD); LPS + Vit.D3 12.5 ng, 954 +/- 483 (N), 912 +/- 510 (CRF), 875 +/- 527 (HD)].	Nitrogen	19-20	vitrin	Homo sapiens	171-174
9881155-8	1998	Moreover, the levels of ASN2 and ASN1 mRNA are also reciprocally regulated by carbon and nitrogen metabolites.	Nitrogen	89-97	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	33-37
9881155-9	1998	The distinct regulation of ASN1 and ASN2 genes combined with their distinct encoded isoenzymes suggest that they may play different roles in nitrogen metabolism, as discussed in this paper.	Nitrogen	141-149	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	27-31
9755482-1	1998	Washed human erythrocytes incubated with glucose and S8 and purged with N2 produced H2S at a nearly constant rate of 170 mumol (L cells)-1 min-1, which continued for several hours.	Nitrogen	72-74	CD59 molecule (CD59 blood group)	Homo sapiens	139-144
9786854-4	1998	In zinc-limited cells, ZRT1 is a stable, N-glycosylated plasma membrane protein.	Nitrogen	41-42	high-affinity Zn(2+) transporter ZRT1	Saccharomyces cerevisiae S288C	23-27
9746757-0	1998	DNA-Dependent protein kinase activity correlates with clinical and in vitro sensitivity of chronic lymphocytic leukemia lymphocytes to nitrogen mustards.	Nitrogen	135-143	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	0-28
9771860-0	1998	Perioperative growth hormone treatment increases nitrogen and fluid balance and results in short-term and long-term conservation of lean tissue mass.	Nitrogen	49-57	growth hormone 1	Homo sapiens	14-28
9781667-1	1998	Rat liver DT-diaphorase (EC 1.6.99.2) catalyzed reductive N-denitration of tetryl (2,4,6-tri-nitrophenyl-N-methylnitramine) and 2,4-dinitrophenyl-N-methylnitramine, oxidizing the excess of NADPH.	Nitrogen	58-59	NAD(P)H quinone dehydrogenase 1	Rattus norvegicus	10-23
9781667-3	1998	Quantitatively, the reactions of DT-diaphorase proceeded like single-electron reductive N-denitration of tetryl by ferredoxin:NADP+ reductase (EC 1.18.1.2) (Shah, M.M.	Nitrogen	88-89	NAD(P)H quinone dehydrogenase 1	Rattus norvegicus	33-46
9781667-9	1998	Thus, although reductive N-denitration of nitrophenyl-N-nitramines is a net two-electron (hydride) transfer process, DT-diaphorase catalyzed the reaction in a single-electron way.	Nitrogen	25-26	NAD(P)H quinone dehydrogenase 1	Rattus norvegicus	117-130
9758807-12	1998	S. cerevisiae strains lacking URE2 function could improve alcoholic fermentation of natural media where proline and other poorly assimilated amino acids are the major potential nitrogen source, as is the case for most fruit juices and grape musts.	Nitrogen	177-185	glutathione peroxidase	Saccharomyces cerevisiae S288C	30-34
9746757-1	1998	The objective of this study is to investigate the role of DNA-dependent protein kinase (DNA-PK) in the chronic lymphocytic leukemia (CLL) lymphocyte response to nitrogen mustard therapy.	Nitrogen	161-169	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	58-86
9746757-1	1998	The objective of this study is to investigate the role of DNA-dependent protein kinase (DNA-PK) in the chronic lymphocytic leukemia (CLL) lymphocyte response to nitrogen mustard therapy.	Nitrogen	161-169	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	88-94
9746757-11	1998	The increase in DNA-PK activity might contribute to the enhanced cross-link repair that we previously postulated to be a primary mechanism of resistance to nitrogen mustards in CLL.	Nitrogen	156-164	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	16-22
10395247-5	1998	PL-Im was therefore N-glycosylated at both Asn79 and Asn128.	Nitrogen	20-21	prolactin family 3, subfamily D, member 1	Rattus norvegicus	0-5
10395247-7	1998	In the Nb2 cell bioassay for lactogenic hormones, recPL-Im and its mutants all had growth-promoting activity but there was a decline in the growth-stimulating potency following decreases in N-glycosylation, i.e. the order of relative potencies was the wild type&gt;N128Q&gt; N79Q&gt;N79Q/N128Q, suggesting that the N-linked oligosaccharides are important in the mitogenic action of the PL-Im.	Nitrogen	7-8	prolactin family 3, subfamily D, member 1	Rattus norvegicus	53-58
9810145-4	1998	Pretreatment of rats with iNOS inhibitor aminoguanidine, however, suppressed the development of proximal tubule epithelial cell injury and prevented an increase in blood urea nitrogen and serum creatinine as well as resulting in a marked fall in iNOS mRNA and protein in rats with HgCl2-induced ARF.	Nitrogen	175-183	nitric oxide synthase 2	Rattus norvegicus	26-30
9719680-7	1998	Sequential digestion of SPACR with N- and O-glycosidases results in a systematic increase in electrophorectic mobility, indicating the presence of both N- and O-linked glycoconjugates.	Nitrogen	35-36	interphotoreceptor matrix proteoglycan 1	Homo sapiens	24-29
19002782-4	1998	Overexpression of this 170 kDa N-glycosylated plasma membrane protein in mammalian cells has been associated with ATP-dependent reduced drug accumulation, suggesting that P-glycoprotein may act as an energy-dependent drug efflux pump.	Nitrogen	31-32	ATP binding cassette subfamily B member 1	Homo sapiens	171-185
9812273-0	1998	Using milk urea nitrogen to predict nitrogen excretion and utilization efficiency in lactating dairy cows.	Nitrogen	36-44	Weaning weight-maternal milk	Bos taurus	6-10
9733643-2	1998	Recombinant nidogen-2 was purified as a 200 kDa protein from transfected mammalian cell medium, showed a high level of N and O-glycosylation, and could be clearly distinguished from nidogen-1 (150 kDa) by specific antibodies.	Nitrogen	119-120	nidogen 2	Homo sapiens	12-21
9825830-11	1998	These results strongly suggest that back oxidation and N-dealkylation of reduced haloperidol in human liver microsomal preparations are mediated by CYP3A4.	Nitrogen	55-56	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	148-154
9801832-2	1998	The crystal structure reveals that both the amide carbonyl oxygen and the terminal amino nitrogen of Gly-Tyr coordinate to the active site zinc ion of CPA in a bidentate fashion, whereby the zinc-bound water molecule is displaced by the amino group.	Nitrogen	89-97	carboxypeptidase A1	Homo sapiens	151-154
9746345-0	1998	The transient association of ERp57 with N-glycosylated proteins is regulated by glucose trimming.	Nitrogen	40-41	protein disulfide isomerase family A member 3	Homo sapiens	29-34
9756240-12	1998	In keeping with these findings, the mean daily nitrogen balance was significantly less negative in the GH-treated subjects than in the vehicle-injected patients (mean of the 4 week daily urine collections -185.7+/-40.33 vs -363.9+/-55.47 mmol/d, P &lt; 0.05, respectively).	Nitrogen	47-55	growth hormone 1	Homo sapiens	103-105
9715532-5	1998	Expression of GmNRT2 in roots was regulated by the type of nitrogen source provided to plants: GmNRT2 mRNA levels were barely detectable in ammonium-grown plants, higher in nitrogen-deprived plants, and highest in nitrate-grown plants.	Nitrogen	59-67	NRT2 protein	Glycine max	14-20
9715532-5	1998	Expression of GmNRT2 in roots was regulated by the type of nitrogen source provided to plants: GmNRT2 mRNA levels were barely detectable in ammonium-grown plants, higher in nitrogen-deprived plants, and highest in nitrate-grown plants.	Nitrogen	173-181	NRT2 protein	Glycine max	14-20
29711062-1	1998	A rare, structurally characterized mu1 ,eta1 -hydrazonato complex is a probable intermediate in the Pd-catalyzed N-arylation of hydrazones.	Nitrogen	113-114	glutathione S-transferase mu 1	Homo sapiens	35-38
9705959-3	1998	Full-length NP is cotranslationally glycosylated in the lumen of the endoplasmic reticulum at two sites distal to the major H2-Kk and H2-Db restricted CTL epitopes, and we show here that pharmacological or genetic inhibition of N-linked glycosylation, leads to the processing and presentation of both these epitopes in a TAP-independent way.	Nitrogen	12-13	SEC14 like lipid binding 2	Homo sapiens	321-324
9733666-3	1998	An overlay of terfenadine and dextromethorphan, a known substrate of CYP2D6, showed that it was possible to superimpose the site of hydroxylation (t-butyl group) and the nitrogen atom of terfenadine with similar regions in dextromethorphan.	Nitrogen	170-178	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	69-75
9733534-2	1998	Here we show that the circadian rhythm controlling the activity of sucrose phosphate synthase (SPS) and nitrate reductase (NR), key control points of carbon and nitrogen metabolism in plant cells, is delayed in tomato by chilling treatments.	Nitrogen	162-170	nitrate reductase [NADH]	Solanum lycopersicum	105-122
9733534-2	1998	Here we show that the circadian rhythm controlling the activity of sucrose phosphate synthase (SPS) and nitrate reductase (NR), key control points of carbon and nitrogen metabolism in plant cells, is delayed in tomato by chilling treatments.	Nitrogen	162-170	nitrate reductase [NADH]	Solanum lycopersicum	124-126
9739616-4	1998	rat liver microsomes, the N-demethylation activities of S-(+)- and R-(-)-Chp decreased continuously up to the third day after the treatment with CCl4, and reached about 9 and 13% of control values, respectively, and the stereoselective N-demethylation of Chp was not observed.	Nitrogen	26-27	C-C motif chemokine ligand 4	Rattus norvegicus	145-149
9698230-1	1998	A chromatographic method was developed for quantitative analysis of site-specific microheterogeneity of the two N-linked glycosylation sites in recombinant human interferon-gamma produced from Chinese hamster ovary (CHO) cell culture.	Nitrogen	112-113	interferon gamma	Homo sapiens	162-178
9753780-11	1998	TCH4 is glycosylated in vivo; glycosidases that remove N-linked glycosylation eliminated 98% of the XET activity.	Nitrogen	55-56	xyloglucan:xyloglucosyl transferase 33	Arabidopsis thaliana	100-103
9754931-6	1998	The antiproliferative action of these analogues was associated with profound shape change in neuro-2A neuroblastoma involving extensive neuritogenesis and an associated increase in neural cell adhesion molecule (NCAM) prevalence at points of cell-cell contact, the latter exhibiting a dose-dependent increase when the n-alkyl chain was extended to five carbon units.	Nitrogen	5-6	neural cell adhesion molecule 1	Mus musculus	181-210
9754931-6	1998	The antiproliferative action of these analogues was associated with profound shape change in neuro-2A neuroblastoma involving extensive neuritogenesis and an associated increase in neural cell adhesion molecule (NCAM) prevalence at points of cell-cell contact, the latter exhibiting a dose-dependent increase when the n-alkyl chain was extended to five carbon units.	Nitrogen	5-6	neural cell adhesion molecule 1	Mus musculus	212-216
9704231-3	1998	Recent data in GDM show that 1) the rate of irreversible nitrogen loss as measured by the rate of urea synthesis in GDM is similar to that in normal pregnancy and is less than that in nonpregnant women; and 2) possibly related to the magnitude of metabolic decompensation as assessed by the nature of therapeutic intervention (diet or diet plus insulin), the rate of protein turnover measured by leucine kinetics is increased in insulin-treated GDM.	Nitrogen	57-65	insulin	Homo sapiens	345-352
9701342-3	1998	We show here that an inhibitor of proteolytic process of apoptosis, N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK), protected hippocampal neuronal damage by inhibition of the DNA fragmentation in a dose-dependent manner and that TPCK induced an apoptosis-regulating molecule, Bcl-2 protein, in the surviving neurons.	Nitrogen	68-69	BCL2 apoptosis regulator	Homo sapiens	279-284
9707526-0	1998	Lotus corniculatus nodulation specificity is changed by the presence of a soybean lectin gene Plant lectins have been implicated as playing an important role in mediating recognition and specificity in the Rhizobium-legume nitrogen-fixing symbiosis.	Nitrogen	224-232	LOW QUALITY PROTEIN: lectin	Glycine max	82-88
9739616-5	1998	Moreover, in the liver microsomes at the 7th day after the treatment with CCl4, the N-demethylation activities of both enantiomers recovered to an original level, and the stereoselective N-demethylation of Chp was again observed.	Nitrogen	84-85	C-C motif chemokine ligand 4	Rattus norvegicus	74-78
9739616-8	1998	On the other hand, in the liver microsomes of a male rat at the 7th day after the treatment with CCl4, the anti-rat CYP2C11 serum had an inhibitory effect on the rates of microsomal N-demethylation of either S-(+)- or R-(-)-enantiomers again.	Nitrogen	182-183	C-C motif chemokine ligand 4	Rattus norvegicus	97-101
9739616-10	1998	These results indicated that the changes of N-demethylation activities of Chp in the CCl4-induced hepatic injury were due to the variation of microsomal CYP2C11.	Nitrogen	44-45	C-C motif chemokine ligand 4	Rattus norvegicus	85-89
9662557-10	1998	With 30 microM NS 1619 (a BKCa channel activator), V1/2 values were shifted by 39 mV to the left (hyperpolarizing direction) and k values were not affected.	Nitrogen	15-17	calcium-activated potassium channel subunit alpha-1	Oryctolagus cuniculus	26-30
9668061-0	1998	Dimerization of the human MUC2 mucin in the endoplasmic reticulum is followed by a N-glycosylation-dependent transfer of the mono- and dimers to the Golgi apparatus.	Nitrogen	83-84	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	26-30
9668061-4	1998	Inhibition of N-glycosylation with tunicamycin treatment slowed down the rate of dimerization and introduced further oligomerization of the MUC2 apomucin in the endoplasmic reticulum.	Nitrogen	14-15	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	140-144
9668061-6	1998	The non-N-glycosylated species of the MUC2 mucin were retained in the endoplasmic reticulum because no O-glycosylated species were precipitated after inhibition by tunicamycin.	Nitrogen	8-9	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	38-42
9641632-5	1998	ESCA survey spectra of samples coated with 1 microg/mL of fibronectin showed an increase in organic nitrogen and carbon compared with uncoated controls.	Nitrogen	100-108	fibronectin 1	Homo sapiens	58-69
9625870-0	1998	Differential inhibition of N and P/Q Ca2+ currents by 5-HT1A and 5-HT1D receptors in spinal neurons of Xenopus larvae.	Nitrogen	27-28	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled L homeolog	Xenopus laevis	54-71
9677662-5	1998	The nitrogen balance (assessed on the basis of the urea nitrogen production rate and nitrogen intake) was assessed retrospectively and correlated with insulin requirements, immunosuppression and the clinical course.	Nitrogen	4-12	insulin	Homo sapiens	151-158
9714307-1	1998	A series of N-substituted heteroaromatic compounds structurally related to clotrimazole was synthesized, and the effects of these compounds on ethosuximide clearance in rats were determined as a measure of their abilities to induce cytochrome P4503A (CYP3A) activity.	Nitrogen	12-13	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	232-238
9642163-0	1998	Interleukin-2 induces N-glycosylation in T-cells: characterization of human lymphocyte oligosaccharyltransferase.	Nitrogen	22-23	interleukin 2	Homo sapiens	0-13
9642163-4	1998	N-glycosylation activity remained elevated during long-term culture and expansion of human lymphocytes when growth was supported by interleukin-2.	Nitrogen	0-1	interleukin 2	Homo sapiens	132-145
9662428-1	1998	We examined cytokinin and nitrate responsiveness in gene expression of five distinct response regulator homologs (ARR3-ARR7) in the leaves of nitrogen-starved Arabidopsis plants.	Nitrogen	142-150	response regulator 3	Arabidopsis thaliana	114-118
9662428-5	1998	These findings suggest that ARRs are involved in inorganic nitrogen signal transduction mediated by cytokinin as in the case of ZmCip1, a response regulator homolog recently identified in maize.	Nitrogen	59-67	cytokinin response regulator 1	Zea mays	128-134
9714307-1	1998	A series of N-substituted heteroaromatic compounds structurally related to clotrimazole was synthesized, and the effects of these compounds on ethosuximide clearance in rats were determined as a measure of their abilities to induce cytochrome P4503A (CYP3A) activity.	Nitrogen	12-13	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	251-256
9641178-8	1998	TNF-alpha showed a significant negative linear correlation with retinol binding protein (RBP) (r=-0.37, n=34, P&lt;0.05), and venous pH (r=-0.4, n=42, P&lt;0.01); also, TNF-alpha values higher than 65 pg/ml were inversely associated with transferrin, cholesterol, blood urea nitrogen (BUN) and CCK.	Nitrogen	275-283	tumor necrosis factor	Homo sapiens	0-9
9669550-4	1998	Porphyrin core size correlations yield a porphyrin-centre to pyrrole-nitrogen distance of 2.00 A for MP11, suggestive of a six-coordinate species in a distorted heme environment.	Nitrogen	69-77	non-compact myelin associated protein	Homo sapiens	101-105
9614172-0	1998	Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae.	Nitrogen	0-8	amino acid permease GAP1	Saccharomyces cerevisiae S288C	41-45
9614172-1	1998	Addition of ammonium ions to yeast cells growing on proline as the sole nitrogen source induces rapid inactivation and degradation of the general amino acid permease Gap1 through a process requiring the Npi1/Rsp5 ubiquitin (Ub) ligase.	Nitrogen	72-80	amino acid permease GAP1	Saccharomyces cerevisiae S288C	166-170
9570794-4	1998	When expressed in pheochromocytoma (PC12) cells with a replication-deficient adenovirus, neurexophilin 1 was rapidly N-glycosylated and then slowly processed to a smaller mature form, probably by endoproteolytic cleavage.	Nitrogen	117-118	neurexophilin 1	Rattus norvegicus	89-104
9646302-2	1998	Exogenous GH improves nitrogen metabolism in patients undergoing surgery; however, the anabolic effects of GH in cases of multiple injury, burn, and sepsis are equivocal.	Nitrogen	22-30	growth hormone 1	Homo sapiens	10-12
9692515-5	1998	There was evidence of an increase in mPAP, MDA, PAF and ET-1 in the plasma, and activity of PLA2, PAF and ET-1 of the lung tissues when the rats inhaled a 10% mixture of oxygen in nitrogen.	Nitrogen	180-188	endothelin 1	Rattus norvegicus	106-110
11670380-0	1998	Synthesis of Vinylene-Co,N-Linked Multi(porphyrin)s by the Addition of Free-Base Porphyrins to a C(2)H(2) Complex of Cobalt(III) Porphyrin and Their Oxidative Rearrangement to Vinylene-N,N"-Linked Multi(porphyrin)s. The nucleophilic addition reaction of a pyrrole nitrogen of free-base porphyrins to a pi-complexed acetylene ligand in a cationic Co(III) porphyrin intermediate afforded good yields of vinylene-Co,N"-linked bis(porphyrin)s, (Por)Co(III)-CH=CH-(N-Por)H(2).	Nitrogen	264-272	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	124-127
11670380-0	1998	Synthesis of Vinylene-Co,N-Linked Multi(porphyrin)s by the Addition of Free-Base Porphyrins to a C(2)H(2) Complex of Cobalt(III) Porphyrin and Their Oxidative Rearrangement to Vinylene-N,N"-Linked Multi(porphyrin)s. The nucleophilic addition reaction of a pyrrole nitrogen of free-base porphyrins to a pi-complexed acetylene ligand in a cationic Co(III) porphyrin intermediate afforded good yields of vinylene-Co,N"-linked bis(porphyrin)s, (Por)Co(III)-CH=CH-(N-Por)H(2).	Nitrogen	264-272	cytochrome p450 oxidoreductase	Homo sapiens	81-84
11670380-0	1998	Synthesis of Vinylene-Co,N-Linked Multi(porphyrin)s by the Addition of Free-Base Porphyrins to a C(2)H(2) Complex of Cobalt(III) Porphyrin and Their Oxidative Rearrangement to Vinylene-N,N"-Linked Multi(porphyrin)s. The nucleophilic addition reaction of a pyrrole nitrogen of free-base porphyrins to a pi-complexed acetylene ligand in a cationic Co(III) porphyrin intermediate afforded good yields of vinylene-Co,N"-linked bis(porphyrin)s, (Por)Co(III)-CH=CH-(N-Por)H(2).	Nitrogen	264-272	cytochrome p450 oxidoreductase	Homo sapiens	129-132
11670380-4	1998	These organometallic Co(III) complexes underwent facile oxidative migration of the Co-bound vinyl group to a porphyrin pyrrole nitrogen when treated with Fe(III) salts or HClO(4) to provide moderate to good yields of Co(II) vinylene-N,N"-linked multi(porphyrin) complexes.	Nitrogen	127-135	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	21-28
11670380-4	1998	These organometallic Co(III) complexes underwent facile oxidative migration of the Co-bound vinyl group to a porphyrin pyrrole nitrogen when treated with Fe(III) salts or HClO(4) to provide moderate to good yields of Co(II) vinylene-N,N"-linked multi(porphyrin) complexes.	Nitrogen	127-135	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	24-27
11670380-4	1998	These organometallic Co(III) complexes underwent facile oxidative migration of the Co-bound vinyl group to a porphyrin pyrrole nitrogen when treated with Fe(III) salts or HClO(4) to provide moderate to good yields of Co(II) vinylene-N,N"-linked multi(porphyrin) complexes.	Nitrogen	127-135	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	217-223
9585360-5	1998	In the SALS patient, the mutation substitutes serine for an asparagine that might be involved in N-linked glycosylation of the EAAT2 protein.	Nitrogen	97-98	solute carrier family 1 member 2	Homo sapiens	127-132
9581827-4	1998	The X-ray crystallography clearly shows that the alkylaminoethoxy side chain of raloxifene causes a specific and inappropriate molecular perturbation of the LBD and that the nitrogen in the side chain must hydrogen bond with aspartate 351 in the LBD of ER.	Nitrogen	174-182	estrogen receptor 1	Homo sapiens	253-255
9560429-0	1998	The rnf gene products in rhodobacter capsulatus play an essential role in nitrogen fixation during anaerobic DMSO-dependent growth in the dark The rnf genes in Rhodobacter capsulatus are essential for nitrogen fixation in the light.	Nitrogen	74-82	tripartite motif containing 31	Homo sapiens	4-7
9560429-0	1998	The rnf gene products in rhodobacter capsulatus play an essential role in nitrogen fixation during anaerobic DMSO-dependent growth in the dark The rnf genes in Rhodobacter capsulatus are essential for nitrogen fixation in the light.	Nitrogen	74-82	tripartite motif containing 31	Homo sapiens	5-8
9560429-0	1998	The rnf gene products in rhodobacter capsulatus play an essential role in nitrogen fixation during anaerobic DMSO-dependent growth in the dark The rnf genes in Rhodobacter capsulatus are essential for nitrogen fixation in the light.	Nitrogen	75-83	tripartite motif containing 31	Homo sapiens	4-7
9560429-0	1998	The rnf gene products in rhodobacter capsulatus play an essential role in nitrogen fixation during anaerobic DMSO-dependent growth in the dark The rnf genes in Rhodobacter capsulatus are essential for nitrogen fixation in the light.	Nitrogen	75-83	tripartite motif containing 31	Homo sapiens	5-8
9560429-4	1998	These results indicate that rnf gene products play an essential role in nitrogen fixation without any functional link to the cyclic electron transport system.	Nitrogen	73-81	tripartite motif containing 31	Homo sapiens	29-32
9560305-1	1998	Cytochrome P-450 CYP2D6, human debrisoquine hydroxylase, metabolizes more than 30 prescribed drugs, the vast majority of which are small molecules containing a basic nitrogen atom.	Nitrogen	166-174	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	17-23
9555075-0	1998	Proteolytic processing of a secreted glycoprotein and O-glycosylation of mannoproteins are affected in the N-glycosylation mutant Saccharomyces cerevisiae ldb1.	Nitrogen	107-108	Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1	Saccharomyces cerevisiae S288C	155-159
9555075-3	1998	Hernandez, Glycobiology, 7 (1997) 487-497], we described the isolation and characterization of the Saccharomyces cerevisiae ldb1 mutant which is affected in several steps of the N-glycosylation of mannoproteins probably due to a malfunction of the Golgi apparatus.	Nitrogen	178-179	Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1	Saccharomyces cerevisiae S288C	124-128
9635877-2	1998	They are thought to be metabolically activated by N-hydroxylation, catalysed by cytochrome P450 (CYP), followed by O-acetylation catalysed by N-acetyltransferases.	Nitrogen	50-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	80-95
9571246-2	1998	We show here that addition of Mn2+ greatly alleviates defects of pmr1 mutants in N-linked and O-linked protein glycosylation.	Nitrogen	81-82	Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1	Saccharomyces cerevisiae S288C	65-69
9635877-2	1998	They are thought to be metabolically activated by N-hydroxylation, catalysed by cytochrome P450 (CYP), followed by O-acetylation catalysed by N-acetyltransferases.	Nitrogen	50-51	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	97-100
9635877-7	1998	The higher adduct levels observed in cells treated with the N-OH metabolites suggests that N-hydroxylation is the rate-limiting step in HMECs and this may be due to low CYP levels.	Nitrogen	60-61	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	169-172
9597543-0	1998	The ALG10 locus of Saccharomyces cerevisiae encodes the alpha-1,2 glucosyltransferase of the endoplasmic reticulum: the terminal glucose of the lipid-linked oligosaccharide is required for efficient N-linked glycosylation.	Nitrogen	199-200	dolichyl-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-dolichol alpha-1,2- glucosyltransferase	Saccharomyces cerevisiae S288C	4-9
9596633-10	1998	Both the mutant analysis and gene regulation studies suggest that GLU1 plays a major role in photorespiration and also plays a role in primary nitrogen assimilation in leaves, whereas the GLU2 gene may play a major role in primary nitrogen assimilation in roots.	Nitrogen	231-239	glutamate synthase 2	Arabidopsis thaliana	188-192
9611819-10	1998	Deletion of URE2 in the gln1-37 background prevented repression of gene expression by ammonia, showing that the ammonia-induced repression is not caused by a general stress response but represents a specific signal for nitrogen catabolite regulation.	Nitrogen	219-227	glutathione peroxidase	Saccharomyces cerevisiae S288C	12-16
9611819-9	1998	Ure2p has been shown to be an essential element for nitrogen-regulated gene expression.	Nitrogen	52-60	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-5
9628026-9	1998	These results, taken together, suggest that ZmCip1 is a primary response gene to cytokinins, and that it involves, at least in part, the nitrogen-signal transduction mediated by cytokinin in maize.	Nitrogen	137-145	cytokinin response regulator 1	Zea mays	44-50
9554877-5	1998	Incorporation of this amino acid residue into the model revealed additional interactions between the guanidine group and the nitrogen atoms of quinoline-containing CysLT1 antagonists.	Nitrogen	125-133	cysteinyl leukotriene receptor 1	Homo sapiens	164-170
9524252-6	1998	The transcript level of pss1+ was moderately abundant during steady-state growth at 25 degrees C and increased a few-fold upon shifting to 42 degrees C. Furthermore, transcription of pss1+ increased in nitrogen-starved conditions.	Nitrogen	202-210	CDP-diacylglycerol-serine O-phosphatidyltransferase	Saccharomyces cerevisiae S288C	24-28
9562246-1	1998	The evolutionarily conserved dolichol-P-dependent N-acetylglucosamine-1-P transferase gene, ALG7, functions by initiating the dolichol pathway of protein N-glycosylation.	Nitrogen	50-51	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	92-96
9502265-4	1998	The present study using the cat carotid body demonstrates profound changes in the levels of immunoreactivity of the catecholamine-synthesizing enzyme, tyrosine hydroxylase, and the neuropeptide, substance P, in response to a two-week exposure to hypoxia (10% O2 in 90% N2).	Nitrogen	269-271	tyrosine hydroxylase	Homo sapiens	151-171
9502265-4	1998	The present study using the cat carotid body demonstrates profound changes in the levels of immunoreactivity of the catecholamine-synthesizing enzyme, tyrosine hydroxylase, and the neuropeptide, substance P, in response to a two-week exposure to hypoxia (10% O2 in 90% N2).	Nitrogen	269-271	tachykinin precursor 1	Homo sapiens	195-206
9531513-8	1998	The Km for formation of N-dealkylated tolterodine by CYP3A4 was similar to that obtained in human liver microsomes and higher for CYP2C9 and -2C19.	Nitrogen	24-25	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	53-59
9531513-9	1998	We conclude from these studies that the formation of 5-HM is catalyzed by CYP2D6 and that the formation of N-dealkylated tolterodine is predominantly catalyzed by CYP3A isoenzymes in human liver microsomes.	Nitrogen	107-108	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	163-168
9604298-16	1998	In contrast with ZAL, the NADPH-dependent N-deethylation of M2 to M1 proceeded at only a very low rate with both human liver microsomes and cDNA-expressed CYP3A4.	Nitrogen	26-27	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	155-161
9524252-6	1998	The transcript level of pss1+ was moderately abundant during steady-state growth at 25 degrees C and increased a few-fold upon shifting to 42 degrees C. Furthermore, transcription of pss1+ increased in nitrogen-starved conditions.	Nitrogen	202-210	CDP-diacylglycerol-serine O-phosphatidyltransferase	Saccharomyces cerevisiae S288C	183-187
29711084-1	1998	Dry air is the source of molecular nitrogen for reactions with TiL4 , Li, and TMSCl (L = Cl, OiPr; TMS = trimethylsilyl).	Nitrogen	35-43	toll like receptor 2	Homo sapiens	63-67
9521739-1	1998	Inducible nitric oxide synthase (iNOS; EC 1.14.13.39) catalyzes the NADPH-dependent oxidation of one of the free guanidino nitrogens of L-Arg to form nitric oxide and L-citrulline.	Nitrogen	123-132	nitric oxide synthase 2	Homo sapiens	0-31
9521739-1	1998	Inducible nitric oxide synthase (iNOS; EC 1.14.13.39) catalyzes the NADPH-dependent oxidation of one of the free guanidino nitrogens of L-Arg to form nitric oxide and L-citrulline.	Nitrogen	123-132	nitric oxide synthase 2	Homo sapiens	33-37
9546665-5	1998	Recently, we have reported that N-linked carbohydrate chains of N-terminal fragment (residues 137-247) obtained from endo-beta-galactosidase-digested ZPB are involved mainly in sperm binding [Yonezawa, N., Mitsui, S., Kudo, K. &amp; Nakano, M. (1997) Eur.	Nitrogen	32-33	zona pellucida glycoprotein 4	Sus scrofa	150-153
9514644-5	1998	At this latter detergent concentration, the activity of prenylated protein methyltransferase (PPMT) was strongly inhibited and that of l-isoaspartyl/d-aspartylmethyltransferase (PIMT) was increased twofold, as measured with their respective exogenous substrates, N-acetyl-S-farnesyl cysteine and ovalbumin.	Nitrogen	263-264	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	Rattus norvegicus	178-182
9546665-8	1998	In this study, we separated the intact neutral N-linked chains from the ZPB/ZPC mixture into diantennary chains and triantennary and tetraantennary chains by affinity chromatography on Concanavalia ensiformis agglutinin.	Nitrogen	47-48	zona pellucida glycoprotein 4	Sus scrofa	72-75
9545574-8	1998	PLP-G cDNA encodes for a predicted 266 amino acid protein containing a 30 amino acid signal peptide and six putative N-linked glycosylation sites.	Nitrogen	8-9	prolactin family 7, subfamily a, member 1	Mus musculus	0-5
9497363-4	1998	TIGR cDNA encodes an olfactomedin-related glycoprotein of 504 amino acids with motifs for N- and O-linked glycosylation, glycosaminoglycan initiation, hyaluronic acid binding, and leucine zippers.	Nitrogen	7-8	myocilin	Homo sapiens	0-4
9524553-0	1998	Bis(dialkyl)dithiocarbamato cobalt(III) complexes of bidentate nitrogen mustards: synthesis, reduction chemistry and biological evaluation as hypoxia-selective cytotoxins.	Nitrogen	63-71	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	35-38
10099230-2	1998	The human interleukin-2 (IL-2) mutant glycoprotein variant IL-Mu6, which bears a novel N-glycosylation site (created by a single amino acid exchange of Gln100 to Asn), was produced under different defined protein-free culture conditions in the presence or absence of either glutamine, NH4Cl, or glucosamine.	Nitrogen	87-88	interleukin 2	Homo sapiens	10-23
10099230-2	1998	The human interleukin-2 (IL-2) mutant glycoprotein variant IL-Mu6, which bears a novel N-glycosylation site (created by a single amino acid exchange of Gln100 to Asn), was produced under different defined protein-free culture conditions in the presence or absence of either glutamine, NH4Cl, or glucosamine.	Nitrogen	87-88	interleukin 2	Homo sapiens	25-29
10099239-7	1998	A core N-glycosylation at fused IL-1beta fragment is likely to play a critical role in directing the high-level secretion of rhG-CSF, and the O-glycosylation of secreted rhG-CSF seems nearly negligible.	Nitrogen	7-8	interleukin 1 beta	Homo sapiens	32-40
9524553-1	1998	Cobalt(III) complexes [Co(R2dtc)2(L)]+ containing two dithiocarbamate ligands (R = Me, Et, pyrrolidine) and a bidentate nitrogen mustard ligand (L) have been prepared as potential hypoxia-selective cytotoxins.	Nitrogen	120-128	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	7-10
9539194-1	1998	OBJECTIVE: To determine if insulin treatment combined with a generous protein intake would normalize whole-body protein kinetics and nitrogen balance in obese subjects with Type 2 diabetes mellitus when compared to obese nondiabetic subjects: 1) during weight-maintenance and 2) after a very low energy diet (VLED).	Nitrogen	133-141	insulin	Homo sapiens	27-34
9539194-7	1998	CONCLUSION: Sufficient exogenous insulin to near-normalize glycaemia improves the altered protein metabolism in hyperglycaemic diabetic subjects during isoenergetic feeding, and restores nitrogen equilibrium better than with VLED alone.	Nitrogen	187-195	insulin	Homo sapiens	33-40
9565882-9	1998	Results indicated that there is an opportunity to increase milk protein production by using RUP formulations that are balanced for AA while minimizing waste N excretion.	Nitrogen	157-158	Weaning weight-maternal milk	Bos taurus	59-63
9486977-6	1998	The increase in VCAM-1 by n-LDL results in increased monocyte binding to HCAEC which can be attenuated by inhibiting the intracellular calcium rise or by blocking the VCAM-1 binding sites.	Nitrogen	5-6	vascular cell adhesion molecule 1	Homo sapiens	16-22
9486977-6	1998	The increase in VCAM-1 by n-LDL results in increased monocyte binding to HCAEC which can be attenuated by inhibiting the intracellular calcium rise or by blocking the VCAM-1 binding sites.	Nitrogen	5-6	vascular cell adhesion molecule 1	Homo sapiens	167-173
9551918-0	1998	Distinct patterns of folding and interactions with calnexin and calreticulin in human class I MHC proteins with altered N-glycosylation.	Nitrogen	120-121	calreticulin	Homo sapiens	64-76
9539069-1	1998	BACKGROUND: Human recombinant growth hormone (rhGH) has been shown to increase skeletal muscle protein synthesis and improve nitrogen balance in critically ill patients and those undergoing surgery.	Nitrogen	125-133	growth hormone 1	Homo sapiens	30-44
9510368-4	1998	Drosophila-expressed DRB1*0401 molecules revealed a decreased N-linked glycosylation as compared to DRB1*0401 molecules purified from a human B-cell line.	Nitrogen	62-63	major histocompatibility complex, class II, DR beta 1	Homo sapiens	21-25
9600717-12	1998	These results show that CYP 3A4 is the primary hepatic CYP isoform mediating the N-demethylation of adinazolam and NDMAD.	Nitrogen	81-82	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	24-31
9600717-12	1998	These results show that CYP 3A4 is the primary hepatic CYP isoform mediating the N-demethylation of adinazolam and NDMAD.	Nitrogen	81-82	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	24-27
9492005-3	1998	Herein, however, we demonstrate that Ly-49A recognizes Dd mutants lacking N-glycosylation.	Nitrogen	74-75	killer cell lectin-like receptor, subfamily A, member 1	Mus musculus	37-43
9782622-1	1998	Growth hormone is an anabolic hormone that causes increased cell growth, positive nitrogen and calcium balance, lipolysis, hyperglycemia, and promotes protein synthesis.	Nitrogen	82-90	growth hormone 1	Homo sapiens	0-14
9526091-2	1998	Ethanolamides of fatty acids are the most well-studied species of this group; an alternative pathway for their biosynthesis includes hydrolysis of N-acylated phosphatidylethanolamines by phospholipase D. Ethanolamides of fatty acids bind to the cannabinoid receptors of the central nervous system (CB1) or peripheral tissues (CB2) and can be considered as endogenous ligands of these receptors.	Nitrogen	147-148	cannabinoid receptor 1	Homo sapiens	298-301
9461008-10	1998	There was one treatment-related death after a course of MTX --&gt; bolus FUra/n-beta-IFN and grade III-IV toxicity occurred in 18% of the patients.	Nitrogen	11-12	interferon alpha 1	Homo sapiens	85-88
10353723-6	1998	Levels of the mRNA encoding the fusion protein were also increased by tunicamycin, but not thapsigargin, suggesting that, in agreement with our previous observations, inhibition of N-linked glycosylation may increase the stability of calreticulin mRNA.	Nitrogen	16-17	calreticulin	Homo sapiens	234-246
9618044-3	1998	In general, N-substituted analogs are distinguished from the non-N-substituted analogs because they (i) are susceptible to radiolysis, (ii) induce cytotoxicity by apoptosis but not necrosis, (iii) inhibit cell proliferation, (iv) activate poly adenosine diphosphate ribosyl transferase (poly ADPRT), and (v) have a much-reduced effect on microregional tumor blood perfusion.	Nitrogen	12-13	poly(ADP-ribose) polymerase 1	Homo sapiens	292-297
9442933-0	1998	Nitrogen balance and mineral excretion in growing male pigs injected with a human growth hormone-releasing factor analog.	Nitrogen	0-8	growth hormone releasing hormone	Homo sapiens	82-113
9458630-2	1998	The authors present evidence from human and animal studies suggesting that growth hormone induces a positive nitrogen balance, enhances connective-tissue synthesis, and increases lean body mass.	Nitrogen	109-117	growth hormone 1	Homo sapiens	75-89
9394039-5	1998	xP4 in the esophagus and in the stomach differ by their N-glycosylation patterns.	Nitrogen	56-57	trefoil factor 3 gene 8 L homeolog	Xenopus laevis	0-3
10520751-6	1998	HM-1 contains no obvious hydrophobic N-terminal cleavable signal sequence, and no potential N-glycosylation sites, but does contain three highly conserved motifs present in U1-70K splicing factors, and contains numerous C-terminal Arg/Asp and Arg/Glu dipeptides characteristic of "RD" family members that function as regulators of mRNA splicing.	Nitrogen	37-38	small nuclear ribonucleoprotein U11/U12 subunit 35	Homo sapiens	0-4
9451015-10	1998	Inhibition of N-glycosylation by tunicamycin retarded, but did not inhibit, dimerization, indicating that N-glycans play a role in efficient dimerization of MUC2 precursors.	Nitrogen	14-15	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	157-161
9916431-2	1998	New method of elimination of SRCL consisted in transcutaneous puncture and drainage of the infected cavity followed by transdrainage laser irradiation of its walls by Nitrogen UV laser and Helium-Neon laser of visible spectrum, was applied in 31 patients.	Nitrogen	167-175	collectin subfamily member 12	Homo sapiens	29-33
9440509-7	1998	CLN3 mRNA levels are also positively regulated by nitrogen sources, but phosphorus and sulfur limitation do not affect CLN3 message levels.	Nitrogen	50-58	cyclin CLN3	Saccharomyces cerevisiae S288C	0-4
9595384-1	1998	It has been shown previously that N-glycosylation of Asn-144 and/or Asn-627 is important for functional expression of neutral endopeptidase-24.11 (NEP).	Nitrogen	34-35	membrane metalloendopeptidase	Homo sapiens	118-145
9595384-1	1998	It has been shown previously that N-glycosylation of Asn-144 and/or Asn-627 is important for functional expression of neutral endopeptidase-24.11 (NEP).	Nitrogen	34-35	membrane metalloendopeptidase	Homo sapiens	147-150
10091156-0	1998	Acute metabolic effects of human growth hormone on 15N-nitrogen balance in patients with thalassaemia as compared to patients with other types of short stature.	Nitrogen	55-63	growth hormone 1	Homo sapiens	33-47
9459175-0	1997	Relationship between nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) and protein expression of Bcl-2, Bax, Bcl-X and p53.	Nitrogen	21-29	BCL2 apoptosis regulator	Homo sapiens	127-132
9436998-2	1998	We have identified a gene, FLO11, that encodes a cell wall protein which is critically required for both invasion and pseudohyphae formation in response to nitrogen starvation.	Nitrogen	156-164	Flo11p	Saccharomyces cerevisiae S288C	27-32
9436998-6	1998	Upon transfer to nitrogen starvation media, however, FLO11 transcripts accumulate in diploid cells, but not in haploids.	Nitrogen	17-25	Flo11p	Saccharomyces cerevisiae S288C	53-58
10388095-29	1998	From this structural relationship, there are, therefore, two reasonable ways to inhibit aromatase: * by occupying the steroid-binding site of the enzyme with a compound such as formestane (Lentaron&amp;reg;), or * by binding the iron with nitrogen-containing compounds such as aminoglutethimide (Orimeten&amp;reg;), the oldest aromatase inhibitor.	Nitrogen	239-247	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	88-97
10388095-31	1998	Other new aromatase inhibitors such as fadrozole (Afema&amp;reg;) and letrozole (Femara&amp;reg;) are orally active nitrogen-containing compounds that bind the heme iron of aromatase.	Nitrogen	116-124	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	10-19
9491429-2	1998	Moreover, on stimulation with lipopolysaccharide and/or interferon-gamma, spleen cells from malaria-cured mice showed an increased capacity to produce tumor necrosis factor, interleukin 6, and reactive nitrogen intermediates as compared with spleen cells from naive mice.	Nitrogen	202-210	interferon gamma	Mus musculus	56-72
9459175-0	1997	Relationship between nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) and protein expression of Bcl-2, Bax, Bcl-X and p53.	Nitrogen	21-29	BCL2 associated X, apoptosis regulator	Homo sapiens	134-137
9459175-0	1997	Relationship between nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) and protein expression of Bcl-2, Bax, Bcl-X and p53.	Nitrogen	21-29	BCL2 like 1	Homo sapiens	139-144
9459175-0	1997	Relationship between nitrogen mustard drug resistance in B-cell chronic lymphocytic leukemia (B-CLL) and protein expression of Bcl-2, Bax, Bcl-X and p53.	Nitrogen	21-29	tumor protein p53	Homo sapiens	149-152
9388263-1	1997	It has been shown that the relative reaction preference of the C4 thiol ester toward oxygen and nitrogen nucleophiles upon activation by proteinase depends on whether residue 1106 is aspartate or histidine (Dodds, A. W., Ren, X.-D., Willis, A. C., and Law, S. K. A.	Nitrogen	96-104	renin	Homo sapiens	221-224
9589778-5	1997	Therefore acid-base and nitrogen homoeostasis are normally attuned to one another through the co-ordinated action of growth hormone/IGF-1 on substrate fluxes.	Nitrogen	24-32	growth hormone 1	Homo sapiens	117-131
9412558-3	1997	Recombinant human growth hormone (rhGH) treatment has been proposed to improve nitrogen balance and to increase muscle strength in these patients.	Nitrogen	79-87	growth hormone 1	Homo sapiens	18-32
9589778-6	1997	However during starvation ketoacid production as the consequence of incomplete fatty acid oxidation and ketone excretion swamps the basogenic limb and full-blown metabolic acidosis prevails; under this condition growth hormone"s effectiveness in sparing nitrogen for anabolic processes is curtailed as glutamate (emanating from the liver) and glutamine (derived from muscle proteolysis) are directed to the kidneys, supporting ammoniogenesis: nitrogen balance is now sacrificed for acid-base homoeostasis.	Nitrogen	443-451	growth hormone 1	Homo sapiens	212-226
9589778-5	1997	Therefore acid-base and nitrogen homoeostasis are normally attuned to one another through the co-ordinated action of growth hormone/IGF-1 on substrate fluxes.	Nitrogen	24-32	insulin like growth factor 1	Homo sapiens	132-137
9589778-6	1997	However during starvation ketoacid production as the consequence of incomplete fatty acid oxidation and ketone excretion swamps the basogenic limb and full-blown metabolic acidosis prevails; under this condition growth hormone"s effectiveness in sparing nitrogen for anabolic processes is curtailed as glutamate (emanating from the liver) and glutamine (derived from muscle proteolysis) are directed to the kidneys, supporting ammoniogenesis: nitrogen balance is now sacrificed for acid-base homoeostasis.	Nitrogen	254-262	growth hormone 1	Homo sapiens	212-226
9384580-5	1997	In contrast, a constitutively active allele of GPA2 stimulates filamentation, even on nitrogen-rich media.	Nitrogen	86-94	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	47-51
9431831-12	1997	CONCLUSIONS: These results strongly suggest that the N-dealkylation of HAL in human liver microsomal preparations is mediated by CYP3A4.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	129-135
9384596-0	1997	The Cln3 cyclin is down-regulated by translational repression and degradation during the G1 arrest caused by nitrogen deprivation in budding yeast.	Nitrogen	109-117	cyclin CLN3	Saccharomyces cerevisiae S288C	4-8
9384580-10	1997	Our findings suggest that GPA2 is an element of the nitrogen sensing machinery that regulates pseudohyphal differentiation by modulating cAMP levels.	Nitrogen	52-60	guanine nucleotide-binding protein subunit alpha	Saccharomyces cerevisiae S288C	26-30
9384596-3	1997	We show here that the Cln3 cyclin, which has a key role in the timely activation of SBF (Swi4-Swi6)- and MBF (Mbp1-Swi6)-dependent promoters in late G1, is down-regulated rapidly at a post-transcriptional level in cells deprived of the nitrogen source.	Nitrogen	236-244	cyclin CLN3	Saccharomyces cerevisiae S288C	22-26
9384596-4	1997	In addition to the fact that Cln3 is degraded faster by ubiquitin-dependent mechanisms, we have found that translation of the CLN3 mRNA is repressed approximately 8-fold under nitrogen deprivation conditions.	Nitrogen	176-184	cyclin CLN3	Saccharomyces cerevisiae S288C	126-130
9409822-2	1997	We have found that at a permissive temperature for growth, the sec13-1 mutation selectively blocks transport of the nitrogen-regulated amino acid permease, Gap1p, from the Golgi to the plasma membrane, but does not affect the activity of constitutive permeases such as Hip1p, Can1p, or Lyp1p.	Nitrogen	116-124	amino acid permease GAP1	Saccharomyces cerevisiae S288C	156-161
9389541-3	1997	One of these proteins, designated PRL-like protein E (PLP-E), is predicted to be synthesized as a precursor of 265 amino acids, modified by N-linked glycosylation, and secreted as a mature glycoprotein of 236 residues.	Nitrogen	140-141	prolactin family 7, subfamily a, member 1	Mus musculus	34-52
9389541-3	1997	One of these proteins, designated PRL-like protein E (PLP-E), is predicted to be synthesized as a precursor of 265 amino acids, modified by N-linked glycosylation, and secreted as a mature glycoprotein of 236 residues.	Nitrogen	140-141	prolactin family 7, subfamily a, member 1	Mus musculus	54-59
9409822-5	1997	Mutations in LST4 and LST7 reduce the activity of the nitrogen-regulated permeases Gap1p and Put4p, whereas mutations in LST8 impair the activities of a broader set of amino acid permeases.	Nitrogen	54-62	amino acid permease GAP1	Saccharomyces cerevisiae S288C	83-88
16501446-1	1997	Branched-chain amino acids (BCAA: leucine, isoleucine and valine) are not just structural constituents of proteins, but have ""pharmacologic"" properties, known for several years: BCAA are catabolized mainly in muscle; can be oxidized with energy production, being nitrogen donors for other amino acids; regulate protein synthesis and degradation; modulate metabolism of neuroactive mediators.	Nitrogen	265-273	AT-rich interaction domain 4B	Homo sapiens	28-32
9436116-0	1997	Milk urea nitrogen as a tool to monitor the protein nutrition of dairy cows.	Nitrogen	10-18	Weaning weight-maternal milk	Bos taurus	0-4
16501446-1	1997	Branched-chain amino acids (BCAA: leucine, isoleucine and valine) are not just structural constituents of proteins, but have ""pharmacologic"" properties, known for several years: BCAA are catabolized mainly in muscle; can be oxidized with energy production, being nitrogen donors for other amino acids; regulate protein synthesis and degradation; modulate metabolism of neuroactive mediators.	Nitrogen	265-273	AT-rich interaction domain 4B	Homo sapiens	180-184
9409285-7	1997	Alterations in apoB conformation and their impact on degradation were also investigated by using DTT and by inhibiting N-linked glycosylation with tunicamycin.	Nitrogen	119-120	apolipoprotein B	Homo sapiens	15-19
9370449-3	1997	All fully hydrated N-acyl PEs with even chain lengths from C-12 to C-18 exhibit sharp endothermic chain-melting phase transitions in the absence of salt and in 1 M NaCl.	Nitrogen	19-20	Bardet-Biedl syndrome 9	Homo sapiens	67-71
9321513-5	1997	Rabbit polyclonal antibodies to CYP3A4 decreased initial rates of N-demethylation of the antihormones by up to 82%, whereas antibodies to CYP2C9 were not inhibitory.	Nitrogen	66-67	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	32-38
9382964-0	1997	Growth hormone prevents prednisolone-induced increase in functional hepatic nitrogen clearance in normal man.	Nitrogen	76-84	growth hormone 1	Homo sapiens	0-14
9382964-11	1997	RESULTS: Growth hormone decreased functional hepatic nitrogen clearance (l/h) by 21% (from 38.8+/-1.8 l/h (control) to 30.5+/-2.7 l/h (4 d growth hormone) (mean+/-SE) (ANOVA; p&lt;0.05)).	Nitrogen	53-61	growth hormone 1	Homo sapiens	9-23
11670155-5	1997	The N-(trimethylsilyl)-substituted was characterized by X-ray crystallography: monoclinic, P2(1)/a, a = 12.585(3) A, b = 12.211(2) A, c = 14.003(2) A, beta = 101.86(2) degrees, V = 2106.0(7) A(3), and Z = 4.	Nitrogen	4-5	cyclin dependent kinase inhibitor 1A	Homo sapiens	91-96
11670166-11	1997	The charge distribution in Tp(Cum,Me)Co(3,5-DBSQ) is Co(II)-SQ, rather than the more common Co(III)-Cat, due to surprisingly weak donation by the Tp(Cum,Me) nitrogens.	Nitrogen	157-166	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	53-59
9335950-5	1997	Hypochlorous acid is only generated by the phagocytic enzyme myeloperoxidase, which can also generate tyrosyl radical and reactive nitrogen intermediates.	Nitrogen	131-139	myeloperoxidase	Homo sapiens	61-76
9427525-6	1997	Our phylogenetic analysis based on the amino acid sequence of the sema domains and the location of conserved N-glycosylation sites suggested that the sema domain of Sema Z belongs to a new class, class VI.	Nitrogen	109-110	semaphorin 6B	Rattus norvegicus	165-171
9453908-3	1997	Administration of GH after elective general surgery improves nitrogen balance.	Nitrogen	61-69	growth hormone 1	Homo sapiens	18-20
21528263-6	1997	An A to G nucleotide substitution giving rise to an amino acid substitution (Asn--&gt;Asp) in codon 21 at the first potential N-glycosylation site of the P-glycoprotein was seen in primary tumors from four patients and in an axillar lymph node metastases from one of these patients.	Nitrogen	126-127	ATP binding cassette subfamily B member 1	Homo sapiens	154-168
33863175-16	1997	For example, high levels of N deposition onto previously N-limited systems leads to increased nitrification, which produces 15 N-enriched NH4 and N-depleted NO3 .	Nitrogen	28-29	NBL1, DAN family BMP antagonist	Homo sapiens	157-160
9399579-10	1997	M-LGP85 contains 11 potential N-glycosylation sites which are heavily glycosylated, resulting in the increased Mr of M-LGP85 present in the mouse liver lysosomes.	Nitrogen	30-31	scavenger receptor class B, member 2	Mus musculus	0-7
9399579-10	1997	M-LGP85 contains 11 potential N-glycosylation sites which are heavily glycosylated, resulting in the increased Mr of M-LGP85 present in the mouse liver lysosomes.	Nitrogen	30-31	scavenger receptor class B, member 2	Mus musculus	117-124
33863175-16	1997	For example, high levels of N deposition onto previously N-limited systems leads to increased nitrification, which produces 15 N-enriched NH4 and N-depleted NO3 .	Nitrogen	57-58	NBL1, DAN family BMP antagonist	Homo sapiens	157-160
33863175-16	1997	For example, high levels of N deposition onto previously N-limited systems leads to increased nitrification, which produces 15 N-enriched NH4 and N-depleted NO3 .	Nitrogen	57-58	NBL1, DAN family BMP antagonist	Homo sapiens	157-160
9295302-9	1997	N-Glycosylation of Asn19 and Asn23 provides the first direct experimental evidence that MRP has an extracytosolic NH2 terminus.	Nitrogen	0-1	ATP binding cassette subfamily C member 1	Homo sapiens	88-91
9430382-11	1997	The n-6 PUFAs are a bit of a worry: while arachidonic acid levels in muscle phospholipid has linked positively to insulin action in our studies, linoleic is negative.	Nitrogen	4-5	insulin	Homo sapiens	114-121
9298962-4	1997	Alteration of the nucleotides flanking the platinum lesion modulated HMG1domA recognition in this series by over 2 orders of magnitude and revealed an unprecedented preference for N2 = dA &gt; T &gt; dC.	Nitrogen	180-182	high mobility group box 1 pseudogene 5	Homo sapiens	69-73
9375395-5	1997	They were glycosylated in the yeast cells, although VPE is not glycosylated in plant cells in spite of the presence of two N-linked glycosylation sites.	Nitrogen	123-124	vacuolar-processing enzyme	Ricinus communis	52-55
9311621-5	1997	This was confirmed by studies with recombinant CYP2D6 expressed in yeast, which was also shown to effect the N-demethylation of MeAmp.	Nitrogen	109-110	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	47-53
9323540-0	1997	Improved high-performance liquid chromatographic method for N-acetylgalactosamine-4-sulfate sulfatase (arylsulfatase B) activity determination using uridine diphospho-N-acetylgalactosamine-4-sulfate.	Nitrogen	60-61	arylsulfatase B	Bos taurus	103-118
9308609-0	1997	Paradoxical positive nitrogen balance in burn patients receiving high-dose administration of insulin for nutritional care.	Nitrogen	21-29	insulin	Homo sapiens	93-100
9308609-1	1997	BACKGROUND: Nitrogen balance in patients who need high-dose administration of insulin has not been evaluated clinically.	Nitrogen	12-20	insulin	Homo sapiens	78-85
9308609-2	1997	The purpose of this study was to compare the difference in nitrogen balance between burn patients who received high-dose administration of insulin and those who did not.	Nitrogen	59-67	insulin	Homo sapiens	139-146
9299393-2	1997	The infectivity of HIV-1 from the cells stimulated with phorbol 12-myristate 13-acetate (PMA) was suppressed by pretreatment with N-myristoyl glycinal diethylacetal (N-Myr-GOA), a potent N-myristoylation inhibitor, and the blockage of myristoylation resulted in accumulation of immature gag precursors.	Nitrogen	130-131	tripartite motif containing 47	Homo sapiens	172-175
9299404-0	1997	Deregulation of the first N-glycosylation gene, ALG7, perturbs the expression of G1 cyclins and cell cycle arrest in Saccharomyces cerevisiae.	Nitrogen	26-27	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	48-52
9299404-1	1997	The evolutionarily conserved ALG7 gene encodes the dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT) and functions by initiating the dolichol pathway of protein N-glycosylation.	Nitrogen	72-73	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	29-33
9310364-0	1997	Identification of an N-glycosylated region of pig zona pellucida glycoprotein ZPB that is involved in sperm binding.	Nitrogen	21-22	zona pellucida glycoprotein 4	Sus scrofa	78-81
9310364-3	1997	Recently, we have shown that N-linked carbohydrate chains of endo-beta-galactosidase-digested ZPB (EbetaG-ZPB) are predominantly involved in sperm binding [Yonezawa, N., Aoki, H., Hatanaka, Y.	Nitrogen	29-30	zona pellucida glycoprotein 4	Sus scrofa	94-97
9309219-10	1997	The guanine N2 amine can bond to Im on its own side of the groove, but not on the cytosine side, because of limits on close approach of the two Im rings and the geometry of sp2 hybridization about the amide nitrogen.	Nitrogen	207-215	Sp2 transcription factor	Homo sapiens	173-176
9310364-3	1997	Recently, we have shown that N-linked carbohydrate chains of endo-beta-galactosidase-digested ZPB (EbetaG-ZPB) are predominantly involved in sperm binding [Yonezawa, N., Aoki, H., Hatanaka, Y.	Nitrogen	29-30	zona pellucida glycoprotein 4	Sus scrofa	106-109
9309219-12	1997	Side-by-side Im and Py rings differentiate GC from CG base pairs because of tight steric contacts and sp2 hybridization at the amine nitrogen atom, with the favored conformations being G/Im,Py/C and C/Py,Im/G.	Nitrogen	133-141	Sp2 transcription factor	Homo sapiens	102-105
9278210-2	1997	The aim of this study was to investigate the role of CYP3A in the in vivo N-demethylation of IMI.	Nitrogen	74-75	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	53-58
9278210-5	1997	CONCLUSIONS: We conclude that CYP3A may play an important role in the in vivo N-demethylation of IMI.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	30-35
11670037-3	1997	Upon oxidation by AgOTf, the dinitrogen ligand of fac-[Re(PPh(3))(PF(3))(dien)(N(2))](+) (3) is replaced with triflate to generate 13, fac-[Re(PPh(3))(PF(3))(dien)(OTf)]OTf, a convenient precursor to rhenium(II) and rhenium(I) amine complexes.	Nitrogen	29-39	FA complementation group C	Homo sapiens	50-53
9274016-0	1997	The Sch9 protein kinase in the yeast Saccharomyces cerevisiae controls cAPK activity and is required for nitrogen activation of the fermentable-growth-medium-induced (FGM) pathway.	Nitrogen	105-113	serine/threonine protein kinase SCH9	Saccharomyces cerevisiae S288C	4-8
9274016-9	1997	Re-addition of nitrogen to cells starved for nitrogen in the presence of glucose failed to trigger activation of trehalase, caused strongly reduced and aberrant repression of CTT1 and SSA3, and failed to induce the upshift in RPL25 expression.	Nitrogen	15-23	catalase T	Saccharomyces cerevisiae S288C	175-179
9256171-13	1997	IGF-I also ameliorated the nephrotoxicity of cyclosporine, with better values of creatinine and blood urea nitrogen (P&lt;0.05).	Nitrogen	107-115	insulin like growth factor 1	Homo sapiens	0-5
9552452-7	1997	Analyses of variance performed using SAS indicated that the degree of N-deacetylation of chitosan significantly affected drug release at pHs 1.2 and 6.8 (p &lt; 0.0001).	Nitrogen	70-71	prostaglandin-endoperoxide synthase 1	Homo sapiens	137-142
9245728-4	1997	In contrast to these predictions we find, based on N-glycosylation analysis in a cell-free and in a cellular system, that the membrane anchor of human, rat, and rabbit mEH displays a type I topology.	Nitrogen	51-52	epoxide hydrolase 1, microsomal	Mus musculus	168-171
9202025-5	1997	In the presence of the NO.-generator diethylamine nonoate, the electron spin resonance spectrum of the PHS-2-derived tyrosyl radical is replaced by the spectrum of another free radical containing a nitrogen atom.	Nitrogen	198-206	prostaglandin-endoperoxide synthase 2	Homo sapiens	103-108
11669965-12	1997	The one-electron oxidation of the hydroxylamine complex with a M(III) porphyrin would be expected to oxidize the N-atom in the coordinated hydroxylamine.	Nitrogen	113-114	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	65-68
9207473-9	1997	These data show that human myeloid calreticulin undergoes cotranslational signal peptide cleavage and posttranslational N-linked glycosylation.	Nitrogen	120-121	calreticulin	Homo sapiens	35-47
9248661-11	1997	Nitrogen-containing systems may also inactivate CYP.	Nitrogen	0-8	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	48-51
11670037-3	1997	Upon oxidation by AgOTf, the dinitrogen ligand of fac-[Re(PPh(3))(PF(3))(dien)(N(2))](+) (3) is replaced with triflate to generate 13, fac-[Re(PPh(3))(PF(3))(dien)(OTf)]OTf, a convenient precursor to rhenium(II) and rhenium(I) amine complexes.	Nitrogen	29-39	FA complementation group C	Homo sapiens	135-138
9225738-3	1997	In vivo hypoxia (5% O2/95% N2 for 30 min) induced mild degenerative neuronal changes (shrunken and eosinophilic somata with picnotic nuclei) in neurons of the CA3, the hilus of the dentate gyrus (DG) and the DG, but not in the CA1.	Nitrogen	27-29	carbonic anhydrase 3	Homo sapiens	159-162
9223567-11	1997	DTZ and its N-desmethyl and N,N-didesmethyl metabolites selectively inhibited CYP3A4 activity, whereas O-desmethyl DTZ was not inhibitory.	Nitrogen	28-31	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	78-84
9223567-0	1997	Role of CYP3A4 in human hepatic diltiazem N-demethylation: inhibition of CYP3A4 activity by oxidized diltiazem metabolites.	Nitrogen	42-43	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	8-14
9207295-8	1997	Lastly, Pept-1 seems to play important roles in nutritional and pharmacological therapies; for example, it has allowed the use of oligopeptides as a source of nitrogen for enteral feeding and the use of oral route for delivery of peptidomimetic drugs such as beta-lactam antibiotics.	Nitrogen	159-167	solute carrier family 15 member 1	Homo sapiens	8-14
9254045-2	1997	Conceivable mevalonate-dependent mechanisms involved in growth control are farnesylation of Ras proteins, regulation of c-myc expression, and N-linked glycosylation of the IGF-1 receptor.	Nitrogen	142-143	insulin like growth factor 1	Homo sapiens	172-177
9254045-10	1997	Taken together, our results provide direct evidence for an important role of dolichyl phosphate as a regulator of cell growth through limiting N-linked glycosylation of the IGF-1 receptor.	Nitrogen	143-144	insulin like growth factor 1	Homo sapiens	173-178
9254049-0	1997	The N-glycosylation sites of soybean seed coat peroxidase.	Nitrogen	4-5	peroxidase	Glycine max	47-57
9253715-3	1997	Cytochrome P4502E1 (CYP2E1) mediated N-hydroxylation results in the formation of N-acetyl-benzo-quinoneimine, a highly reactive intermediate.	Nitrogen	37-38	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	0-18
9253715-3	1997	Cytochrome P4502E1 (CYP2E1) mediated N-hydroxylation results in the formation of N-acetyl-benzo-quinoneimine, a highly reactive intermediate.	Nitrogen	37-38	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	20-26
9223567-16	1997	These findings suggest that N-demethylated metabolites of DTZ may contribute to CYP3A4 inhibition in vivo, especially under conditions in which N-desmethyl DTZ accumulates, such as during prolonged DTZ therapy.	Nitrogen	28-29	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	80-86
9253906-6	1997	Interleukin-6 was elevated and correlated with rectal temperature and nitrogen excretion in both groups.	Nitrogen	70-78	interleukin 6	Homo sapiens	0-13
12223754-7	1997	We propose that N2 fixation in soybean nodules is mediated by both the oxygen-diffusion barrier and the potential to metabolize sucrose via SS.	Nitrogen	16-18	sucrose synthase	Glycine max	140-142
9199164-7	1997	Together, these studies demonstrate that both a nitrogen-sensing mechanism and Sec13p control Gap1p transport from the Golgi to the plasma membrane.	Nitrogen	48-56	amino acid permease GAP1	Saccharomyces cerevisiae S288C	94-99
9182588-0	1997	The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains.	Nitrogen	102-103	alpha-1,2-mannosyltransferase KTR1	Saccharomyces cerevisiae S288C	4-9
9182588-0	1997	The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains.	Nitrogen	102-103	mannosyltransferase KTR3	Saccharomyces cerevisiae S288C	11-16
9148793-2	1997	Reactive intermediates in the oxidation of mixtures of volatile organic compounds (VOCs) and oxides of nitrogen (NOx) play central roles: the hydroxyl radical (OH), during the day; the nitrate radical (NO3), at night; and ozone (O3), which contributes during the day and night.	Nitrogen	103-111	NBL1, DAN family BMP antagonist	Homo sapiens	202-205
9193097-7	1997	In the 5" flanking region of the gene for Fd VI only, we identified NIT-2 motifs, which are widely found in genes for enzymes related to nitrogen metabolism.	Nitrogen	137-145	nitrilase 2	Zea mays	68-73
10453490-8	1997	There was continued release of amino acids from the forearm in the control subjects, while there was marked amino acid uptake in the GH patients (total amino acid nitrogen exchange was -398 +/- 158 mumol/L vs +165 +/- 61 mumol/L, P &lt; 0.01).	Nitrogen	163-171	growth hormone 1	Homo sapiens	133-135
9233544-7	1997	This survey deals with the effect of an increase in diet protein intake and of the separate effects of glucose, glucagon and insulin on functional hepatic nitrogen clearance in normal man and in patients with cirrhosis of the liver.	Nitrogen	155-163	insulin	Homo sapiens	125-132
9233544-16	1997	Insulin is not a direct controller of hepatic nitrogen clearance, but is still considered an important regulator of urea synthesis by its reducing effects on blood amino acid concentration.	Nitrogen	46-54	insulin	Homo sapiens	0-7
9172050-6	1997	In the present study, a molecular lipophilicity potential is used to compare the hydrophobic properties of 49 "heterocyclic sp2 nitrogen" highly potent PAF antagonists, belonging to six structurally different series (nine hetrazepines, five pyrrolo[1,2-c]thiazoles, 14 carboxamides, nine dihydropyridines, nine pyridinyl-thiazolidines and three imidazo[4,5-c]pyridines).	Nitrogen	128-136	Sp2 transcription factor	Homo sapiens	124-127
9153243-0	1997	The thiol-dependent reductase ERp57 interacts specifically with N-glycosylated integral membrane proteins.	Nitrogen	64-65	protein disulfide isomerase family A member 3	Homo sapiens	30-35
9260873-1	1997	The hydrolysis of enkephalin (Enk) congeners by the isolated N- (N-ACE) and C-domain of angiotensin I converting enzyme (ACE) and by the two-domain somatic ACE was investigated.	Nitrogen	61-62	angiotensin I converting enzyme	Homo sapiens	67-70
9260873-1	1997	The hydrolysis of enkephalin (Enk) congeners by the isolated N- (N-ACE) and C-domain of angiotensin I converting enzyme (ACE) and by the two-domain somatic ACE was investigated.	Nitrogen	61-62	angiotensin I converting enzyme	Homo sapiens	88-119
9260873-1	1997	The hydrolysis of enkephalin (Enk) congeners by the isolated N- (N-ACE) and C-domain of angiotensin I converting enzyme (ACE) and by the two-domain somatic ACE was investigated.	Nitrogen	61-62	angiotensin I converting enzyme	Homo sapiens	121-124
9260873-1	1997	The hydrolysis of enkephalin (Enk) congeners by the isolated N- (N-ACE) and C-domain of angiotensin I converting enzyme (ACE) and by the two-domain somatic ACE was investigated.	Nitrogen	61-62	angiotensin I converting enzyme	Homo sapiens	121-124
15096005-11	1997	These findings indicate that pharmacological concentrations of IGF-I may improve clinical outcome and nitrogen utilization in patients with moderate-to-severe head injury.	Nitrogen	102-110	insulin like growth factor 1	Homo sapiens	63-68
9144178-10	1997	The demonstration that DAD1 is a subunit of the OST suggests that induction of a cell death pathway upon loss of DAD1 in the tsBN7 cell line reflects the essential nature of N-linked glycosylation in eukaryotes.	Nitrogen	128-129	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	48-51
9174048-0	1997	Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard.	Nitrogen	80-88	cyclin dependent kinase inhibitor 1A	Homo sapiens	14-18
9174048-0	1997	Cells lacking CIP1/WAF1 genes exhibit preferential sensitivity to cisplatin and nitrogen mustard.	Nitrogen	80-88	cyclin dependent kinase inhibitor 1A	Homo sapiens	19-23
21639304-2	1997	Exhaustive adsorption of Ni(II) or Co(II) complexes, in the 0-4 mug L(-)(1) concentration range, was achieved by vibrationally promoted electrolysis for 3 min of ~25 muL volume samples, hanging under the working electrode in a nitrogen atmosphere.	Nitrogen	227-235	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	35-41
15299933-1	1997	Soybean leghemoglobin a is a small (16 kDa) protein facilitating the transport of O(2) to respiring N(2)-fixing bacteria at low free-O(2) tension.	Nitrogen	100-104	leghemoglobin A	Glycine max	8-21
9212779-6	1997	Consistent with the hypothesis, the three analogs that do contain the nitrogen bridge formed reactive intermediates that could be trapped with glutathione when oxidized by HOCl, myeloperoxidase or activated neutrophils.	Nitrogen	70-78	myeloperoxidase	Homo sapiens	178-193
9139799-1	1997	Using two separate methods, we have determined that all six potential sites for N-linked glycosylation on the rat lutropin/choriogonadotropin receptor (rLHR) contain carbohydrates.	Nitrogen	80-81	luteinizing hormone/choriogonadotropin receptor	Rattus norvegicus	152-156
9141436-4	1997	Western blotting of crude NHL plasma membranes using a carboxyterminal antipeptide antibody showed that NTCP is a 39-kd polypeptide that is N-glycosylated to a final molecular weight of 56 kd.	Nitrogen	26-27	solute carrier family 10 member 1	Homo sapiens	104-108
9161914-9	1997	A good body condition increased the content of whey protein in total milk nitrogen and of gamma-casein in total caseins (P &lt; 0.05); in addition, curd firmness was improved (P &lt; 0.01) and aggregation time was reduced (P &lt; 0.05).	Nitrogen	74-82	Weaning weight-maternal milk	Bos taurus	69-73
9126892-11	1997	These findings indicate that pharmacological concentrations of IGF-I may improve clinical outcome and nitrogen utilization in patients with moderate-to-severe head injury.	Nitrogen	102-110	insulin like growth factor 1	Homo sapiens	63-68
9152603-7	1997	Based on the results of this study, it is concluded that the 14-(R)-hydroxylation and N-demethylation of CLAR is primarily mediated by one or more members of the human liver CYP3A subfamily.	Nitrogen	86-87	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	174-179
9179853-1	1997	The general amino acid permease, Gap1, of Saccharomyces cerevisiae is very active in cells grown on proline as the sole nitrogen source.	Nitrogen	120-128	amino acid permease GAP1	Saccharomyces cerevisiae S288C	33-37
9179853-10	1997	Although the C-terminal region of Gap1p plays an important role in nitrogen control of activity, it was not sufficient to confer this regulation to two NH4(+)-insensitive permeases, namely the arginine (Can1p) and uracil (Fur4p) permeases.	Nitrogen	67-75	amino acid permease GAP1	Saccharomyces cerevisiae S288C	34-39
9100025-2	1997	In this study, we show that N-acylated GCAP1 restored Ca2+ sensitivity of native and recombinant photoreceptor retGC1.	Nitrogen	28-29	guanylate cyclase activator 1A	Homo sapiens	39-44
9170245-5	1997	In this report it is shown that the formation of this enzyme is dependent upon the functional GLN3 gene and that the response to nitrogen availability is under the control of the URE2 gene product.	Nitrogen	129-137	glutathione peroxidase	Saccharomyces cerevisiae S288C	179-183
9147053-1	1997	As part of our ongoing efforts to characterize the N-glycosylation pathway of lepidopteran insect cells, we have isolated an alpha 1,2-mannosidase homolog from an Sf9 cDNA library.	Nitrogen	51-52	mannosidase alpha class 1A member 2	Homo sapiens	125-146
9113345-5	1997	N-demethylation activity has recently been proposed to reflect CYP3A3/4 activity.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	63-69
9113345-9	1997	The Eadie-Hofstee plot of DMO N-demethylation was consistent with single-enzyme Michaelis-Menten kinetics (Vmax varying from 3.3 to 6.8 nmol mg-1 min-1, K(m) from 231 to 322 microM).	Nitrogen	30-31	CD59 molecule (CD59 blood group)	Homo sapiens	146-151
9089636-1	1997	The yeast ALG7 gene functions by initiating the synthesis of the dolichol-linked oligosaccharide precursor and plays an important role in the control of protein N-glycosylation.	Nitrogen	161-162	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	10-14
9145315-5	1997	Inhibition of the N-glycosylation pathway by tunicamycin resulted in a decreased ETSA-B21 signal on the cell membrane.	Nitrogen	18-19	cytohesin 1	Homo sapiens	86-89
9058737-9	1997	The N-acetyl-conjugated sphingols (C2 ceramides) blocked phosphatidylethanol formation indicating that phospholipase D (PLD) is an intracellular target of ceramide action.	Nitrogen	4-5	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	103-118
9126611-5	1997	Results of the expression of WT and N580Q hCox-2 in a Drosophila S2 cell system were also consistent with the N-glycosylation at this site, but low levels of activity were obtained.	Nitrogen	36-37	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	42-48
9126611-6	1997	High levels of N-glycosylation heterogeneity are observed in hCox-2 expressed using recombinant baculovirus (BV) in Sf9 cells.	Nitrogen	15-16	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	61-67
9126611-8	1997	N-linked oligosaccharide profiling of purified VV and BV WT and S582A mutant hCox-2 showed the presence of high mannose structures, (Man)n (GlcNAc)2, n = 9, 8, 7, 6.	Nitrogen	4-5	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	77-83
9058737-9	1997	The N-acetyl-conjugated sphingols (C2 ceramides) blocked phosphatidylethanol formation indicating that phospholipase D (PLD) is an intracellular target of ceramide action.	Nitrogen	4-5	glycosylphosphatidylinositol specific phospholipase D1	Homo sapiens	120-123
9084457-2	1997	At least three different P450s appear to be responsible for the N-demethylation of imipramine to desipramine in vivo: CYP1A2, CYP2C19, and CYP3A4.	Nitrogen	64-65	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	139-145
9045680-6	1997	In addition, the P1 carbonyl of the ketone inhibitor is pointing into the oxyanion hole and forms a hydrogen bond with the peptidic nitrogen of Gly-122, resulting in a different state compared with the tetrahedral intermediate observed in the structure of ICE and CPP32 in complex with an aldehyde inhibitor.	Nitrogen	132-140	caspase 1	Homo sapiens	256-259
9045680-6	1997	In addition, the P1 carbonyl of the ketone inhibitor is pointing into the oxyanion hole and forms a hydrogen bond with the peptidic nitrogen of Gly-122, resulting in a different state compared with the tetrahedral intermediate observed in the structure of ICE and CPP32 in complex with an aldehyde inhibitor.	Nitrogen	132-140	caspase 3	Homo sapiens	264-269
16535546-1	1997	A microbial culture enriched from a diesel fuel-contaminated aquifer was able to grow on 1,3,5-trimethylbenzene (1,3,5-TMB) and 1,2,4-TMB under N(inf2)O-reducing conditions, but it did not degrade 1,2,3-TMB.	Nitrogen	144-145	inverted formin 2	Homo sapiens	146-150
9084457-1	1997	OBJECTIVE: To further substantiate the role of CYP1A2 and CYP3A4 for the N-demethylation in vivo.	Nitrogen	73-74	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	58-64
9172952-6	1997	Vmax/K(M) values of the high-affinity UDP-glucuronosyltransferase(s) (UGTs) exceed those of the low-affinity enzyme(s) severalfold, such that the former should make the major contribution to N-glucuronidation of the drugs at therapeutic concentrations in vivo.	Nitrogen	191-192	beta-1,3-glucuronyltransferase 2	Homo sapiens	38-68
9088001-8	1997	N2 however induced significant elevation in basal prolactin, corticosterone and noradrenaline levels.	Nitrogen	0-2	prolactin	Rattus norvegicus	50-59
9245355-4	1997	The parameters for C-C, C-H, and C-O bonds of sp3 and sp2 hybridized carbons and C-N bonds of sp3 carbons were obtained from 606 equations formed from experimental data from 20 substances taken from the literature.	Nitrogen	83-84	Sp3 transcription factor	Homo sapiens	94-97
9047339-6	1997	All gcv1 strains studied were unable to grow on glycine as a sole nitrogen source and lacked glycine cleavage enzyme activity.	Nitrogen	66-74	glycine decarboxylase subunit T	Saccharomyces cerevisiae S288C	4-8
9132061-13	1997	However, they do show two differences of importance to peroxidase catalysis: (1) the asparagine residue linked with the active site distal histidine via hydrogen bonding is absent; (2) an N-glycosylation site is located right at the entrance to the heme channel.	Nitrogen	188-189	peroxidase	Arabidopsis thaliana	55-65
9090882-11	1997	Deprivation of nitrogen, phosphorus, potassium, and sulfur changed spatial expression as well as the expression level of StPT1.	Nitrogen	15-23	inorganic phosphate transporter	Solanum tuberosum	121-126
9047311-5	1997	Analysis of the P3 structure influence on substrate efficiency demonstrates that compounds which contain D-isomers of N-blocked bulky amino acids, such as Phe, Leu, and Val, in this position are more efficient for tPA than substrates with N-unblocked small amino acids (Ser or Pro) in the P3 position.	Nitrogen	118-119	plasminogen activator, tissue type	Homo sapiens	214-217
9047311-5	1997	Analysis of the P3 structure influence on substrate efficiency demonstrates that compounds which contain D-isomers of N-blocked bulky amino acids, such as Phe, Leu, and Val, in this position are more efficient for tPA than substrates with N-unblocked small amino acids (Ser or Pro) in the P3 position.	Nitrogen	239-240	plasminogen activator, tissue type	Homo sapiens	214-217
9034152-5	1997	In addition, removal of the single N-linked glycosylation site at Asn18 of CD59 resulted in an enhancement of complement inhibitory activity.	Nitrogen	35-36	CD59 molecule (CD59 blood group)	Homo sapiens	75-79
16535510-4	1997	Depending on the imposed pO(inf2), 0.6 to 1.4 mmol of N/day (i.e., 20 to 40% of input N) was emitted as N(inf2).	Nitrogen	54-55	inverted formin 2	Homo sapiens	25-32
9013598-0	1997	Identification of N-linked glycosylation sites in human testis angiotensin-converting enzyme and expression of an active deglycosylated form.	Nitrogen	18-19	angiotensin I converting enzyme	Homo sapiens	63-92
16535510-4	1997	Depending on the imposed pO(inf2), 0.6 to 1.4 mmol of N/day (i.e., 20 to 40% of input N) was emitted as N(inf2).	Nitrogen	86-87	inverted formin 2	Homo sapiens	25-32
9029042-8	1997	1 microM of the CYP3A inhibitor ketoconazole inhibited 37 +/- 19% of the N-demethylation and 86 +/- 5% of 3-hydroxylation.	Nitrogen	73-74	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	16-21
9131945-10	1997	CONCLUSIONS: We conclude that CYPs 3A4, 2C9 and 2D6 together with an unidentified enzyme, but not CYPs 1A2 and 2C19, mediate the N-demethylation of AMI.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	30-43
9076658-4	1997	Experiments with purified CYP2C3 from rabbit liver gave similar results: this enzyme showed the highest activity for phenylacetone formation from benzphetamine (BZP) and showed lower activities with compounds having smaller nitrogen substituents.	Nitrogen	224-232	cytochrome P450 2C3	Oryctolagus cuniculus	26-32
9112220-7	1997	These data suggest that CD34+ cells enriched from frozen apheresis blood products can be either used immediately or stored in liquid nitrogen and thawed with minimal effect on their ability to proliferate and differentiate in liquid culture.	Nitrogen	133-141	CD34 molecule	Homo sapiens	24-28
9023308-6	1997	The percentage contributions of CYP3A4 and CYP2C19 to the overall N-demethylation of CIT in human liver microsomes were estimated using a relative activity factor; respective values of 70% and 7% were calculated for microsomes obtained from livers from putative extensive metabolizers for (S)-mephenytoin 4"-hydroxylation.	Nitrogen	66-67	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	32-38
9076658-8	1997	This result indicated that rat CYP2C enzymes have a more rigid regioselectivity than rabbit CYP2C3 for the deamination/N-dealkylation of phenylisopropylamines.	Nitrogen	119-120	cytochrome P450 2C3	Oryctolagus cuniculus	92-98
9272125-2	1997	We recently reported the use of N-myristoylated PKC-alpha pseudosubstrate peptides with potent PKC-alpha inhibitory activity as reversal agents of drug resistance in MCF-7 MDR cells.	Nitrogen	32-33	protein kinase C alpha	Homo sapiens	48-57
9027506-7	1997	The Eif4g2 polypeptide contains multiple potential N-linked glycosylation sites as well as protein kinase C and casein kinase II phosphorylation sites.	Nitrogen	51-52	eukaryotic translation initiation factor 4 gamma 2	Homo sapiens	4-10
8995397-2	1997	Plant aldehyde oxidase and xanthine dehydrogenase activities are involved in nitrogen metabolism and hormone biosynthesis, and their corresponding genes have not yet been isolated.	Nitrogen	77-85	aldehyde oxidase	Solanum lycopersicum	6-22
9332704-5	1997	We therefore investigated whether changes in the phosphorylation status would influence the activities of the N-acetyltransferases NAT1 and/or NAT2, being responsible for one of the two major pathways leading to the ultimate mutagens, the reactive esters which are derived from the N-hydroxylated metabolites of aromatic amines.	Nitrogen	110-111	N-acetyltransferase 1	Rattus norvegicus	131-135
9275032-5	1997	In a multivariate analysis, the T/N ratio of TIMP-1 mRNA was found to be an independent factor influencing the depth of tumour invasion and was the second most important factor in determining the prognosis of patients.	Nitrogen	34-35	TIMP metallopeptidase inhibitor 1	Homo sapiens	45-51
9110356-1	1997	Using in vitro techniques, the present study demonstrates that CYP2D6, and 3A4 are involved in N-demethylation of citalopram (CIT) enantiomers.	Nitrogen	95-96	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	63-69
9110356-3	1997	cDNA expressed human cytochrome P-450 3A4, 2C19 and 2D6 isozymes, but not CYP1A2, were identified to be involved in N-demethylation of CIT enantiomers.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	21-41
9070359-8	1997	Apparent K(m) and Vmax kinetic constants for N-acetylation were 5- to 10-fold lower for recombinant mouse NAT1 than NAT2.	Nitrogen	45-46	N-acetyltransferase 2 (arylamine N-acetyltransferase)	Mus musculus	116-120
9030779-0	1997	Functional characterization of the N-glycosylation sites of human acid sphingomyelinase by site-directed mutagenesis.	Nitrogen	35-36	sphingomyelin phosphodiesterase 1	Homo sapiens	66-87
9272125-2	1997	We recently reported the use of N-myristoylated PKC-alpha pseudosubstrate peptides with potent PKC-alpha inhibitory activity as reversal agents of drug resistance in MCF-7 MDR cells.	Nitrogen	32-33	protein kinase C alpha	Homo sapiens	95-104
9143866-8	1997	CONCLUSION: It seems that there was a good correspondence between the capacity of drugs to inhibit the O- and N-demethylation of codeine in human liver microsomes and their apparent metabolism by CYP2D6 or CYP3A4, respectively in vivo in man, suggesting that this in vitro inhibition test may be a useful screen for drugs which interact with these two important drug-metabolising enzymes.	Nitrogen	2-3	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	196-202
9143866-1	1997	OBJECTIVE: The O- and N-demethylation of codeine is catalysed by CYP2D6 and CYP3A4 respectively.	Nitrogen	22-23	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	65-71
9143866-8	1997	CONCLUSION: It seems that there was a good correspondence between the capacity of drugs to inhibit the O- and N-demethylation of codeine in human liver microsomes and their apparent metabolism by CYP2D6 or CYP3A4, respectively in vivo in man, suggesting that this in vitro inhibition test may be a useful screen for drugs which interact with these two important drug-metabolising enzymes.	Nitrogen	2-3	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	206-212
9143866-1	1997	OBJECTIVE: The O- and N-demethylation of codeine is catalysed by CYP2D6 and CYP3A4 respectively.	Nitrogen	22-23	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	76-82
16844061-1	1996	Recombinant human growth hormone (rHGH) can improve nitrogen balance and promotecell proliferation.	Nitrogen	52-60	growth hormone 1	Homo sapiens	18-32
9014843-20	1997	In addition, the increase n steady-state concentrations of GnRH receptor and GnRH receptor mRNA induced by E2 is not compromised by concurrent progestin stimulation.	Nitrogen	1-2	gonadotropin-releasing hormone receptor	Ovis aries	59-72
9014843-20	1997	In addition, the increase n steady-state concentrations of GnRH receptor and GnRH receptor mRNA induced by E2 is not compromised by concurrent progestin stimulation.	Nitrogen	1-2	gonadotropin-releasing hormone receptor	Ovis aries	77-90
8967667-4	1996	Treatment with growth hormone for 7 days resulted in weight gain and nitrogen retention, but the long-term effects of this treatment in patients with HIV-associated wasting are not known.	Nitrogen	69-77	growth hormone 1	Homo sapiens	15-29
9171444-7	1997	In the first one, Su(H) binds to inactive N at the membrane.	Nitrogen	42-43	Suppressor of Hairless	Drosophila melanogaster	18-23
9171444-8	1997	The binding of D1 to N in the extracellular space somehow interferes with the N-mediated cytoplasmic retention of Su(H), resulting in the nuclear translocation and "activation" of Su(H).	Nitrogen	21-22	Suppressor of Hairless	Drosophila melanogaster	114-119
9171444-8	1997	The binding of D1 to N in the extracellular space somehow interferes with the N-mediated cytoplasmic retention of Su(H), resulting in the nuclear translocation and "activation" of Su(H).	Nitrogen	21-22	Suppressor of Hairless	Drosophila melanogaster	180-185
9171444-8	1997	The binding of D1 to N in the extracellular space somehow interferes with the N-mediated cytoplasmic retention of Su(H), resulting in the nuclear translocation and "activation" of Su(H).	Nitrogen	78-79	Suppressor of Hairless	Drosophila melanogaster	114-119
9171444-8	1997	The binding of D1 to N in the extracellular space somehow interferes with the N-mediated cytoplasmic retention of Su(H), resulting in the nuclear translocation and "activation" of Su(H).	Nitrogen	78-79	Suppressor of Hairless	Drosophila melanogaster	180-185
8955081-2	1996	Reaction of H2O2 with ferric leghemoglobin (metLb, the monomeric, oxygen-carrying, heme protein from root nodules of nitrogen-fixing plants) has been previously shown to generate an iron(IV)-oxo (ferryl) species and at least one protein radical.	Nitrogen	117-125	leghemoglobin A	Glycine max	29-42
8961954-3	1996	The human (h) PTH/PTHrP receptor is a membrane glycoprotein with an apparent molecular weight of approximately 85000 which contains four putative N-glycosylation sites.	Nitrogen	146-147	parathyroid hormone 1 receptor	Homo sapiens	14-32
8961954-6	1996	Inhibition of N-glycosylation with an optimized concentration of tunicamycin yielded completely nonglycosylated hPTH/PTHrP receptor (approximately 60 kDa).	Nitrogen	14-15	parathyroid hormone	Homo sapiens	112-116
8980650-4	1996	The newly synthesized p31 species was quantitatively converted to p27 by treatment with endoglycosidase H, consistent with efficient N-glycosylation at a site in the N-terminal propeptide region (Asn63-Met64-Thr65).	Nitrogen	133-134	ATPase H+ transporting V1 subunit E1	Homo sapiens	22-25
8942745-4	1996	CYP2E1 protein was detected in liver sections by immunohistochemistry and in hepatic microsomal fractions by immunoblotting; CYP2E1 activity was detected by N-demethylation of N,N-dimethylnltrosamine (NDMA).	Nitrogen	157-158	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	125-131
8973632-0	1996	Biosynthesis and N-glycosylation of human interferon-gamma.	Nitrogen	17-18	interferon gamma	Homo sapiens	42-58
8973632-7	1996	Inhibition of N-glycosylation by tunicamycin dramatically reduced the expression of IFN-gamma, but did not block its secretion.	Nitrogen	14-15	interferon gamma	Homo sapiens	84-93
9022285-6	1996	Anoxia exposure of turtles in vivo, via submergence in N2-gassed water at 7 degrees C, altered the activity and subcellular distribution of PKC in liver.	Nitrogen	55-57	proline rich transmembrane protein 2	Homo sapiens	140-143
8916413-5	1996	Continuous wave (CW) and pulsed EPR studies of the cupric complex of the protein implicate a histidyl nitrogen ligand in metal coordination, as in human transferrin.	Nitrogen	102-110	transferrin	Homo sapiens	153-164
8910558-3	1996	Sequence analysis indicated that Rek is a protein of 873 amino acids with an extracellular region composed of two immunoglobulin-like domains followed by two fibronectin type III domains with eight predicted N-glycosylation sites.	Nitrogen	208-209	AXL receptor tyrosine kinase	Gallus gallus	33-36
8912669-7	1996	.NO gas and the .NO-donors required molecular oxygen to induce the formation of the GAPDH thiyl radical, suggesting the possible involvement of higher nitrogen oxides.	Nitrogen	151-159	glyceraldehyde-3-phosphate dehydrogenase	Homo sapiens	84-89
8875867-0	1996	A modular domain of NifU, a nitrogen fixation cluster protein, is highly conserved in evolution.	Nitrogen	28-36	iron-sulfur cluster assembly enzyme	Homo sapiens	20-24
8875867-1	1996	hnifU, a gene exhibiting similarity to nifU genes of nitrogen fixation gene clusters, was identified in the course of expressed sequence tag (EST) generation from a human fetal heart cDNA library.	Nitrogen	53-61	iron-sulfur cluster assembly enzyme	Homo sapiens	0-5
8875867-1	1996	hnifU, a gene exhibiting similarity to nifU genes of nitrogen fixation gene clusters, was identified in the course of expressed sequence tag (EST) generation from a human fetal heart cDNA library.	Nitrogen	53-61	iron-sulfur cluster assembly enzyme	Homo sapiens	1-5
8875867-3	1996	Conceptual translation of the hnifU cDNA yielded a protein product bearing 77% and 70% amino acid identity to NifU-like hypothetical proteins from Haemophilus influenzae and Saccharomyces cerevisiae, respectively, and 40-44% identity to the N-terminal regions of NifU proteins from several diazatrophs (i.e., nitrogen-fixing organisms).	Nitrogen	309-317	iron-sulfur cluster assembly enzyme	Homo sapiens	30-35
8875867-5	1996	Further, the NifU-like proteins of non-nitrogen-fixing organisms were similar only to the N-terminal region of diazatrophic NifU proteins and therefore identified a novel modular domain in these NifU proteins.	Nitrogen	39-47	iron-sulfur cluster assembly enzyme	Homo sapiens	13-17
8875867-5	1996	Further, the NifU-like proteins of non-nitrogen-fixing organisms were similar only to the N-terminal region of diazatrophic NifU proteins and therefore identified a novel modular domain in these NifU proteins.	Nitrogen	39-47	iron-sulfur cluster assembly enzyme	Homo sapiens	124-128
8875867-5	1996	Further, the NifU-like proteins of non-nitrogen-fixing organisms were similar only to the N-terminal region of diazatrophic NifU proteins and therefore identified a novel modular domain in these NifU proteins.	Nitrogen	39-47	iron-sulfur cluster assembly enzyme	Homo sapiens	124-128
21541594-6	1996	The T/N ratio of alpha 1AT bad a converse correlation with that of MMP7 (p=0.034).	Nitrogen	6-7	serpin family A member 1	Homo sapiens	17-26
8901527-1	1996	Newly synthesized apolipoprotein B (apoB) is degraded by a proteolytic process in the pre-Golgi compartment that can be inhibited by N-acetyl-L-leucinyl-L-leucinyl-L-norleucinal (ALLN) but not by several other protease inhibitors.	Nitrogen	0-1	apolipoprotein B	Homo sapiens	18-34
8901527-1	1996	Newly synthesized apolipoprotein B (apoB) is degraded by a proteolytic process in the pre-Golgi compartment that can be inhibited by N-acetyl-L-leucinyl-L-leucinyl-L-norleucinal (ALLN) but not by several other protease inhibitors.	Nitrogen	0-1	apolipoprotein B	Homo sapiens	36-40
8873592-1	1996	Endothelial nitric oxide synthase (eNOS) is dually acylated by N-myristoylation and cysteine palmitoylation and resides in Golgi and caveolae membranes.	Nitrogen	36-37	nitric oxide synthase 3	Homo sapiens	0-33
8921392-1	1996	Glutamine synthetase (GS) is a ubiquitous enzyme that catalyzes the ATP-dependent conversion of glutamate to glutamine using ammonia as the nitrogen source.	Nitrogen	140-148	glutamate-ammonia ligase	Homo sapiens	0-20
11667621-4	1996	Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the beta-carbon of Trp-2.	Nitrogen	53-61	tRNA-Pro (anticodon AGG) 2-6	Homo sapiens	93-98
8794367-2	1996	Following expression of the UL37 open reading frame in vitro, its signals for translocation and N-glycosylation were recognized by microsomal enzymes.	Nitrogen	96-97	envelope glycoprotein UL37	Human betaherpesvirus 5	28-32
8894516-5	1996	Ciprofloxacin and norfloxacin significantly depressed the N-demethylation of erythromycin by CYP3A4 in human microsomes and by CYP3A2 in rat microsomes.	Nitrogen	58-59	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	93-99
8897021-12	1996	GH and IGF-I may be useful agents to improve nitrogen balance and nutritional status in patients with chronic renal failure.	Nitrogen	45-53	insulin like growth factor 1	Homo sapiens	7-12
8891872-6	1996	We used these drugs to evaluate the affinity of C and N sites in various human tissues involved in the cardiovascular actions of ACE and used [125I]Ro31-8472 as ligand.	Nitrogen	54-55	angiotensin I converting enzyme	Homo sapiens	129-132
8953507-12	1996	Of seven cDNA-expressed P450 isoforms in man (CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2D6, CYP2E1 and CYP3A4), CYP3A4, CYP2D6 and CYP1A2 isozyme exhibited substantial catalytic activity of N-demethylation of YM17E.	Nitrogen	11-12	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	97-103
8923919-6	1996	Curing increments in a nitrogen atmosphere increased the shear strength for two of the three materials tested (P50 and Heliomolar).	Nitrogen	23-31	nuclear factor kappa B subunit 1	Homo sapiens	111-114
8891901-4	1996	[Ca2+]n was also constantly higher than [Ca2+]i after the stimulation of thrombin (0.05 U/ml), FCS (10%), and thapsigargin (Tsg, 1 microM).	Nitrogen	6-7	coagulation factor II, thrombin	Homo sapiens	73-81
8916423-3	1996	The increase in relative abundances of the product ions resulting from the cleavage of the amide bond at the alkylation site (relative to the corresponding cleavage for substance P) can be explained by the increased basicity of the amide nitrogen in the context of the "mobile proton" model.	Nitrogen	238-246	tachykinin precursor 1	Homo sapiens	169-180
8794367-5	1996	Tunicamycin treatment, which inhibits N-glycosylation, increased the rate of migration of the UL37 protein to 68 kDa, verifying its modification by N-glycosylation in HCMV-infected cells.	Nitrogen	148-149	envelope glycoprotein UL37	Human betaherpesvirus 5	94-98
8798661-4	1996	In this report, N-biotinylated analogs of RKRCLRRL that inactivate Ca2+-dependent PKC activity were designed and tested for their ability to covalently label PKC isozymes.	Nitrogen	16-17	protein kinase C alpha	Homo sapiens	158-161
8879142-1	1996	Based on sequence analysis, the protein encoded by the UL3 open reading frame (ORF) of herpes simplex virus type 1 (HSV-1) was predicted to contain an N glycosylation site and to be a glycoprotein.	Nitrogen	151-152	nuclear protein UL3	Human alphaherpesvirus 1	55-58
8879142-5	1996	None of the expressed UL3 protein species were susceptible to tunicamycin treatment, suggesting that they were not N-linked glycosylated.	Nitrogen	0-1	nuclear protein UL3	Human alphaherpesvirus 1	22-25
8798614-5	1996	In this study, we specifically examined how deletion or transposition of the site of N-linked glycosylation in the CD59 polypeptide affects its MAC inhibitory function.	Nitrogen	85-86	CD59 molecule (CD59 blood group)	Homo sapiens	115-119
8798661-5	1996	A purified PKC isozyme mixture (alpha, beta, gamma, epsilon, zeta) was incubated with the N-biotinylated peptides and then subjected to denaturing gel electrophoresis, transferred to nitrocellulose, and probed for avidin-reactive species.	Nitrogen	90-91	protein kinase C alpha	Homo sapiens	11-14
8798614-7	1996	Furthermore, we show that CD59 retains normal MAC regulatory function when mutated to eliminate all potential sites for N-linked glycosylation.	Nitrogen	120-121	CD59 molecule (CD59 blood group)	Homo sapiens	26-30
8798661-4	1996	In this report, N-biotinylated analogs of RKRCLRRL that inactivate Ca2+-dependent PKC activity were designed and tested for their ability to covalently label PKC isozymes.	Nitrogen	16-17	protein kinase C alpha	Homo sapiens	82-85
8798661-9	1996	Inactivation of the Ca2+-dependent PKC subfamily by the N-biotinylated peptides was associated with covalent labeling of the 82-kDa PKC subspecies.	Nitrogen	56-57	protein kinase C alpha	Homo sapiens	35-38
8798661-9	1996	Inactivation of the Ca2+-dependent PKC subfamily by the N-biotinylated peptides was associated with covalent labeling of the 82-kDa PKC subspecies.	Nitrogen	56-57	protein kinase C alpha	Homo sapiens	132-135
8798661-14	1996	These results provide evidence that the N-biotinylated inactivator peptides are active-site affinity labels of PKC.	Nitrogen	40-41	protein kinase C alpha	Homo sapiens	111-114
8794768-2	1996	Proton, nitrogen, and carbon chemical shift assignments have been made for the SH2 domain of Grb2.	Nitrogen	8-16	growth factor receptor bound protein 2	Homo sapiens	93-97
8877032-0	1996	Variable contribution of CYP2D6 to the N-dealkylation of S-(-)-propranolol by human liver microsomes.	Nitrogen	39-40	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	25-31
8809046-0	1996	Induction of calreticulin expression in HeLa cells by depletion of the endoplasmic reticulum Ca2+ store and inhibition of N-linked glycosylation.	Nitrogen	122-123	calreticulin	Homo sapiens	13-25
8877032-6	1996	The two livers with the highest proportion of CYP2D6-mediated N-dealkylation had relatively high ratios of specific CYP2D6 to CYP1A2 activity.	Nitrogen	62-63	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	46-52
8877032-6	1996	The two livers with the highest proportion of CYP2D6-mediated N-dealkylation had relatively high ratios of specific CYP2D6 to CYP1A2 activity.	Nitrogen	62-63	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	116-122
8761309-4	1996	Nucleotide sequence analysis indicated that the Wnt-13 gene encodes the protein of 372 amino acids, including a signal peptide, two potential N-glycosylation sites and 24 cystein residues highly conserved among members of the Wnt gene family.	Nitrogen	0-1	Wnt family member 2B	Homo sapiens	48-54
8764089-4	1996	Enzymatic deglycosylation showed that the PrV UL10 protein is N glycosylated.	Nitrogen	62-63	envelope glycoprotein M	Suid alphaherpesvirus 1	46-50
8756692-4	1996	The amino acid sequence of pig AE2 in the region encompassing the N-glycosylated Z-loop was also determined by RT-PCR.	Nitrogen	66-67	solute carrier family 4 member 2	Sus scrofa	31-34
8702538-10	1996	These observations suggest that a single N-linked glycosylation site located at a similar position in the CD22 and CD33 glycoproteins is critical for regulating ligand recognition by both receptors.	Nitrogen	41-42	CD33 molecule	Homo sapiens	115-119
8707386-6	1996	Ang II significantly increased norepinephrine turnover in the organum vasculosum lamina terminalis and ventral median preoptic nucleus of SHR (organum vasculosum lamina terminalis: 40 +/- 5% by Ang II versus 18 +/- 6% by saline, P &lt; .05; ventral median preoptic nucleus: 32 +/- 3% by Ang II versus 21 +/- 2% by saline, P &lt; .05) but not of WKY (37 +/- 5% versus 29 +/- 5%, P = NS, and 30 +/- 2% versus 32 +/- 3%, P = NS, respectively).	Nitrogen	382-384	angiotensinogen	Rattus norvegicus	0-6
8707386-6	1996	Ang II significantly increased norepinephrine turnover in the organum vasculosum lamina terminalis and ventral median preoptic nucleus of SHR (organum vasculosum lamina terminalis: 40 +/- 5% by Ang II versus 18 +/- 6% by saline, P &lt; .05; ventral median preoptic nucleus: 32 +/- 3% by Ang II versus 21 +/- 2% by saline, P &lt; .05) but not of WKY (37 +/- 5% versus 29 +/- 5%, P = NS, and 30 +/- 2% versus 32 +/- 3%, P = NS, respectively).	Nitrogen	422-424	angiotensinogen	Rattus norvegicus	0-6
8702538-0	1996	A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33.	Nitrogen	9-10	CD22 molecule	Homo sapiens	113-117
8702538-0	1996	A single N-linked glycosylation site is implicated in the regulation of ligand recognition by the I-type lectins CD22 and CD33.	Nitrogen	9-10	CD33 molecule	Homo sapiens	122-126
8702538-4	1996	These observations suggest that N-linked glycosylation sites on the CD22 molecule may play a role in the regulation of CD22-mediated adhesion.	Nitrogen	32-33	CD22 molecule	Homo sapiens	68-72
8702538-4	1996	These observations suggest that N-linked glycosylation sites on the CD22 molecule may play a role in the regulation of CD22-mediated adhesion.	Nitrogen	32-33	CD22 molecule	Homo sapiens	119-123
8702538-5	1996	In this work we have performed site-specific mutagenesis of potential N-linked glycosylation sites on CD22 in an effort to determine whether they might be involved in ligand recognition.	Nitrogen	70-71	CD22 molecule	Homo sapiens	102-106
8702538-6	1996	We show that mutation of a single potential N-linked glycosylation site in the first immunoglobulin domain of CD22 completely abrogates ligand recognition.	Nitrogen	44-45	CD22 molecule	Homo sapiens	110-114
8702538-10	1996	These observations suggest that a single N-linked glycosylation site located at a similar position in the CD22 and CD33 glycoproteins is critical for regulating ligand recognition by both receptors.	Nitrogen	41-42	CD22 molecule	Homo sapiens	106-110
8770173-6	1996	Control and L-selectin groups had similar elevations of serum creatinine (1.8 +/- 0.3 vs. 1.7 +/- 0.2 mg/dl) and blood urea nitrogen (111 +/- 17 vs. 128 +/- 12 mg/dl) 24 h postischemia.	Nitrogen	124-132	selectin, lymphocyte	Mus musculus	12-22
8761433-5	1996	Although under the same conditions the N-acetylation rates for the two NAT1s declined by &gt; 50%, below 5 microM 2-AF or AAB, the NAT rate data fit Michaelis-Menten kinetics, and the apparent K(m) values were 0.2-0.9 microM.	Nitrogen	39-40	N-acetyltransferase 1	Rattus norvegicus	71-75
8875114-7	1996	Cholinesterase, total bilirubin, circulating thrombocytes and blood area nitrogen were the independent predictors of the concentration of soluble VCAM-1.	Nitrogen	73-81	vascular cell adhesion molecule 1	Homo sapiens	146-152
8755910-0	1996	Interaction of the GATA factor Gln3p with the nitrogen regulator Ure2p in Saccharomyces cerevisiae.	Nitrogen	46-54	glutathione peroxidase	Saccharomyces cerevisiae S288C	65-70
8856579-2	1996	Growth hormone (GH) enhances nitrogen retention in patients with chronic obstructive lung disease, sepsis, and in fasted adult volunteers.	Nitrogen	29-37	growth hormone 1	Homo sapiens	0-14
8691455-1	1996	A series of N-acetylated, non-alpha, aromatic amino acids was prepared and shown to promote the absorption of recombinant human growth hormone (rhGH) from the gastrointestinal tract.	Nitrogen	12-13	growth hormone 1	Homo sapiens	128-142
8776899-10	1996	Fusion genes for ERD5 and PUT1 complemented a put1 mutant of yeast, allowing put1 to grow with proline as the source of nitrogen.	Nitrogen	120-128	proline dehydrogenase	Saccharomyces cerevisiae S288C	26-30
8776899-10	1996	Fusion genes for ERD5 and PUT1 complemented a put1 mutant of yeast, allowing put1 to grow with proline as the source of nitrogen.	Nitrogen	120-128	proline dehydrogenase	Saccharomyces cerevisiae S288C	46-50
8776899-10	1996	Fusion genes for ERD5 and PUT1 complemented a put1 mutant of yeast, allowing put1 to grow with proline as the source of nitrogen.	Nitrogen	120-128	proline dehydrogenase	Saccharomyces cerevisiae S288C	77-81
8763845-1	1996	The kinetic basis for the in vitro hypoxia-selective cytotoxicity (HSC) of the Co(III)-nitrogen mustard complex SN 24771 (NSC 675352) has been investigated using pulse radiolysis.	Nitrogen	87-95	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	79-86
8764331-7	1996	Among the recombinant human CYP isoforms, CYP2D6, 2B6, 3A4 and 1A2 catalyzed the 8-hydroxylation, and CYP1A2 and 3A4 were involved exclusively in the N-oxidation, whereas CYP2B6, 2C19, 1A2, 3A4 and 2D6 showed a catalytic activity for the N-demethylation, for either or both of MS enantiomers.	Nitrogen	150-151	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	42-48
8766007-12	1996	A fourth parameter influencing the choline+ transporter is the presence of an OH group on the C atom next to that bearing the N atom (as in choline+) or an ester-OCOR group (acetylcholine+, butyrylcholine+) or a thioester-SCOR-group (acetylthiocholine+, butyrylthiocholine+); or an -OP(OH)2(OR) group (glycerylphosphoryl-choline+), resulting in app.Ki,l,choline+ values of 0.3-1.0 mmol x l-1.	Nitrogen	126-127	solute carrier family 6 member 8	Rattus norvegicus	35-55
8865369-12	1996	These results indicate that the CYP2E1 subfamily is the major enzyme involved in TMO N-demethylation in rat in vitro although the CYP3A2 is also involved in this transformation.	Nitrogen	85-86	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	32-38
8700133-0	1996	Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition.	Nitrogen	13-14	solute carrier family 6 member 2	Homo sapiens	37-63
8660458-6	1996	Unlike other amino-acid permeases, whose expression is nitrogen-source limited, GNP1 is expressed on both rich and poor nitrogen sources.	Nitrogen	55-63	glutamine permease GNP1	Saccharomyces cerevisiae S288C	80-84
8660458-6	1996	Unlike other amino-acid permeases, whose expression is nitrogen-source limited, GNP1 is expressed on both rich and poor nitrogen sources.	Nitrogen	120-128	glutamine permease GNP1	Saccharomyces cerevisiae S288C	80-84
8690531-4	1996	Our results show that association of IFN-gamma and tumor necrosis factor-alpha boosts MIBG uptake in the early times of incubation in LAN-5 and GI-LI-N cells, while both SK-N-SH and SK-N-BE(2)c cells are strongly stimulated by co-treatment with IFN-gamma and all-trans retinoic acid.	Nitrogen	149-151	interferon gamma	Homo sapiens	37-78
8690531-4	1996	Our results show that association of IFN-gamma and tumor necrosis factor-alpha boosts MIBG uptake in the early times of incubation in LAN-5 and GI-LI-N cells, while both SK-N-SH and SK-N-BE(2)c cells are strongly stimulated by co-treatment with IFN-gamma and all-trans retinoic acid.	Nitrogen	149-151	interferon gamma	Homo sapiens	37-46
8660692-1	1996	Cytochrome P450 2D6 (CYP2D6) catalyzes the oxidation of substrates with a positively charged nitrogen atom 5-7 angstroms from the site of the oxidation.	Nitrogen	93-101	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	0-19
8660692-1	1996	Cytochrome P450 2D6 (CYP2D6) catalyzes the oxidation of substrates with a positively charged nitrogen atom 5-7 angstroms from the site of the oxidation.	Nitrogen	93-101	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	21-27
8757790-5	1996	Hypoxia-dependent kinase activation of transcription factors in nitrogen-fixing bacteria bears a striking analogy to the phosphorylation of hypoxia inducible factor-1 (HIF-1) in mammalian cells.	Nitrogen	64-72	hypoxia inducible factor 1 subunit alpha	Homo sapiens	140-166
8757790-5	1996	Hypoxia-dependent kinase activation of transcription factors in nitrogen-fixing bacteria bears a striking analogy to the phosphorylation of hypoxia inducible factor-1 (HIF-1) in mammalian cells.	Nitrogen	64-72	hypoxia inducible factor 1 subunit alpha	Homo sapiens	168-173
8663249-4	1996	However, other 5-HT2A receptor ligands like lysergic acid diethylamide (LSD), in which the amine nitrogen is embedded in a heterocycle, or N,N-dimethyl 5-HT, in which the side chain is a tertiary amine, are found in the computational simulations to interact with the aspartate but not with the serine, due mainly to steric hindrance.	Nitrogen	97-105	5-hydroxytryptamine receptor 2A	Homo sapiens	15-30
8813053-0	1996	Mutational analysis of N-linked glycosylation of esterase 6 in Drosophila melanogaster.	Nitrogen	23-24	Esterase 6	Drosophila melanogaster	49-59
8813053-1	1996	The primary sequence of the esterase 6 (EST6) enzyme of Drosophila melanogaster contains four potential N-linked glycosylation sites, at residues 21, 399, 435, and 485.	Nitrogen	104-105	Esterase 6	Drosophila melanogaster	28-38
8813053-1	1996	The primary sequence of the esterase 6 (EST6) enzyme of Drosophila melanogaster contains four potential N-linked glycosylation sites, at residues 21, 399, 435, and 485.	Nitrogen	104-105	Esterase 6	Drosophila melanogaster	40-44
8667235-5	1996	Thus, the results are consistent with the assumption that the N-demethylation of clomipramine is catalyzed by CYP3A4.	Nitrogen	62-63	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	110-116
8631921-14	1996	Examination of the electrophoretic mobility of the N-linked modified protein invertase in null mutant strains indicates that Ktr1p, Ktr2p, and Yur1p are involved in N-linked glycosylation, possibly as redundant enzymes.	Nitrogen	51-52	alpha-1,2-mannosyltransferase KTR1	Saccharomyces cerevisiae S288C	125-130
8744012-5	1996	Moreover, 1H NMR signal intensities of N-acetyl groups and acetate strongly correlate with the myeloperoxidase activities in synovial fluids from patients with rheumatoid arthritis.	Nitrogen	13-14	myeloperoxidase	Homo sapiens	95-110
10879226-6	1996	Immunoreactive N-acetylated BEP was also not detected in all the placental subfractions.	Nitrogen	15-16	proopiomelanocortin	Homo sapiens	28-31
8631921-14	1996	Examination of the electrophoretic mobility of the N-linked modified protein invertase in null mutant strains indicates that Ktr1p, Ktr2p, and Yur1p are involved in N-linked glycosylation, possibly as redundant enzymes.	Nitrogen	51-52	mannosyltransferase KTR2	Saccharomyces cerevisiae S288C	132-137
8815742-1	1996	An analytical system is presented for rapid assessment of site-specific microheterogeneity of the two potential N-linked glycosylation sites of recombinant human interferon-gamma (IFN-gamma) derived from Chinese hamster ovary cell culture.	Nitrogen	112-113	interferon gamma	Homo sapiens	162-178
8815742-1	1996	An analytical system is presented for rapid assessment of site-specific microheterogeneity of the two potential N-linked glycosylation sites of recombinant human interferon-gamma (IFN-gamma) derived from Chinese hamster ovary cell culture.	Nitrogen	112-113	interferon gamma	Homo sapiens	180-189
8662191-4	1996	The nucleotide sequence of MSS10 is identical to three other genes from S. cerevisiae identified as: FUP1, a gene that enhances iron-limited growth; PHD2, a gene identified for its ability to induce pseudohyphal growth in diploid cells grown on nitrogen-limited media; and MSN1, a gene encoding a transcriptional activator involved in invertase regulation.	Nitrogen	245-253	Msn1p	Saccharomyces cerevisiae S288C	101-105
8640913-2	1996	Previously, we have shown that low CYP3A activity, measured by dapsone N-hydroxylation, and high CYP2D6 activity, assessed by debrisoquine 4-hydroxylation, were significant susceptibility risk factors in developing aggressive bladder cancer.	Nitrogen	71-72	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	35-40
8780046-9	1996	The BCAA transaminase mediated not only the bidrectional transfer of amino groups between leucine or valine and glutamate, but also the direct transfer of nitrogen between leucine and valine.	Nitrogen	155-163	AT-rich interaction domain 4B	Homo sapiens	4-8
8737124-7	1996	The nitrogen atom is possibly the site that binds cytochrome P-450, which catalyses theophylline metabolism.	Nitrogen	4-12	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	50-66
8617950-2	1996	For human HLA-A, -B, and -C class I glycoproteins, position 86 is the only site of N-linked glycosylation.	Nitrogen	83-84	major histocompatibility complex, class I, A	Homo sapiens	10-19
8638929-4	1996	Although no relationship was observed between the levels of CYP2B1/2 and CYP3A, ratios of CYP3A/CYP2B1 plus CYP2B2 contents were invariably higher with hepatocytes treated with N-methylated barbiturates than with the nonmethylated analogs.	Nitrogen	177-178	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	73-78
8627546-4	1996	The kinetics of the N-demethylation of MPTP (1 microM - 3 mM) by microsomes from the liver of an extensive metabolizer with respect to cytochrome P4502D6 (CYP2D6) activity were biphasic (apparent Km1 and Km2 values = 48 and 2882 microM).	Nitrogen	20-21	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	135-153
8627546-4	1996	The kinetics of the N-demethylation of MPTP (1 microM - 3 mM) by microsomes from the liver of an extensive metabolizer with respect to cytochrome P4502D6 (CYP2D6) activity were biphasic (apparent Km1 and Km2 values = 48 and 2882 microM).	Nitrogen	20-21	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	155-161
8611511-0	1996	Expression of the mouse mastocytoma glucosaminyl N-deacetylase/ N-sulfotransferase in human kidney 293 cells results in increased N-sulfation of heparan sulfate.	Nitrogen	49-50	sulfotransferase family 1D, member 1	Mus musculus	64-82
8735845-5	1996	On the other hand, when X = alpha MeTrp, its optimal N-protecting group was 2Adoc and its configuration was preferentially D. In the newly synthesized compounds, 13: 2Adoc-D-alpha MeTrp-Phg-Asp-NalN(CH3)2 and 16: 2Adoc-D-alpha MeTrp-Phg-Asp-NalNH2 had the best CCK-B receptor affinities (KI = 3.5 and 3.4 nM, respectively) and were selected for further biological evaluation.	Nitrogen	53-54	cholecystokinin B receptor	Rattus norvegicus	261-275
8816988-5	1996	In this study, molecular electrostatic potential is used to compare the electronic properties of 48 "heterocyclic sp2 nitrogen" highly potent PAF antagonists, belonging to six series (nine hetrazepines, five pyrrolo[1,2-c]thiazoles, 14 carboxamides, nine dihydropyridines, nine pyridinylthiazolidines and two imidazo[4,5-c]pyridines).	Nitrogen	118-126	Sp2 transcription factor	Homo sapiens	114-117
8860647-5	1996	All three forms cross-reacted with an antibody raised to natural HGL and their treatment with Endo H showed them to be N-linked glycosylation variants of a single polypeptide.	Nitrogen	119-120	lipase F, gastric type	Homo sapiens	65-68
8662135-12	1996	Delivery of agents that antagonize cytokines and other moieties such as glutamine and growth hormone may, in the future, help to restore nitrogen balance during sepsis.	Nitrogen	137-145	growth hormone 1	Homo sapiens	86-100
11666481-2	1996	The deprotonated PMA(-) ligand binds Co(III) via five nitrogens located in primary and secondary amines, a pyrimidine and an imidazole ring, and a peptide moiety.	Nitrogen	54-63	mitochondrially encoded cytochrome c oxidase III	Homo sapiens	37-44
8638929-4	1996	Although no relationship was observed between the levels of CYP2B1/2 and CYP3A, ratios of CYP3A/CYP2B1 plus CYP2B2 contents were invariably higher with hepatocytes treated with N-methylated barbiturates than with the nonmethylated analogs.	Nitrogen	177-178	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	90-95
8700170-6	1996	We find that the CBA/N defect partially impairs both B7-1 and B7-2 induction via CD40.	Nitrogen	21-22	CD80 antigen	Mus musculus	53-66
8636059-1	1996	We present an analysis of the DNA region located upstream of GAP1, the structural gene for the general amino acid permease, which contains the sites required for activation of transcription of this gene in response to the nitrogen source of the growth medium.	Nitrogen	222-230	amino acid permease GAP1	Saccharomyces cerevisiae S288C	61-65
8625627-13	1996	CONCLUSIONS: Daily administration of recombinant growth hormone in mechanically ventilated patients with acute respiratory failure promotes a marked nitrogen retention.	Nitrogen	149-157	growth hormone 1	Homo sapiens	49-63
8861661-6	1996	In addition, in healthy volunteers and cancer patients, the N-demethylation of DM correlated with the CYP3A-mediated metabolism of verapamil and tamoxifen.	Nitrogen	60-61	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	102-107
8778198-12	1996	Triiodothyronine has no effect on functional hepatic nitrogen clearance, but given together with growth hormone, it abolishes the effect of growth hormone on functional hepatic nitrogen clearance.	Nitrogen	177-185	growth hormone 1	Homo sapiens	97-111
8829802-4	1996	Rat transferrin, like other transferrins, had the potential N-linked glycosylation site only in the C-terminal domain, although lactoferrins characterized so far contained the glycosylation sites in both the N- and C-terminal domains.	Nitrogen	60-61	transferrin	Rattus norvegicus	4-15
8854046-2	1996	The study suggests that the "larger" inhibitors (such as the [2"(4"-aminophenyl)alkyl] pyrrolidine-2,5-dione based compounds), after an initial binding of the phenylamine nitrogen lone pair electrons with the Fe3+ haem of the cytochrome P-450, preferentially utilise the region of the AR active site which would normally bind C(17) = O of the substrate.	Nitrogen	171-179	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	226-242
8854046-2	1996	The study suggests that the "larger" inhibitors (such as the [2"(4"-aminophenyl)alkyl] pyrrolidine-2,5-dione based compounds), after an initial binding of the phenylamine nitrogen lone pair electrons with the Fe3+ haem of the cytochrome P-450, preferentially utilise the region of the AR active site which would normally bind C(17) = O of the substrate.	Nitrogen	171-179	cytochrome P450 family 19 subfamily A member 1	Homo sapiens	285-287
8778198-9	1996	All injections were given at 20 00 h. RESULTS: Growth hormone decreased functional hepatic nitrogen clearance (l/h) by 30% (from 33.8 +/- 3.2 l/h (control) to 23.8 +/- 1.5 l/h (10 days growth hormone) (mean +/- SE) (ANOVA; p &lt; 0.01)).	Nitrogen	91-99	growth hormone 1	Homo sapiens	47-61
8778198-10	1996	Triiodothyronine did not change functional hepatic nitrogen clearance (36.7 +/- 3.2 l/h), but triiodothyronine given together with growth hormone abolished the effect of growth hormone functional hepatic nitrogen clearance (38.8 +/- 4.8 l/h).	Nitrogen	204-212	growth hormone 1	Homo sapiens	131-145
8603082-6	1996	One difference between the mouse and Chinese hamster MCT1 is the absence of a predicted external consensus sequence for N-linked glycosylation in the mouse sequence.	Nitrogen	120-121	modifier of curly tail 1	Mus musculus	53-57
8728322-12	1996	In addition, the N-terminal Cys residue of the plasma CETP is not required for its activity.	Nitrogen	17-18	cholesteryl ester transfer protein	Oryctolagus cuniculus	54-58
8778198-10	1996	Triiodothyronine did not change functional hepatic nitrogen clearance (36.7 +/- 3.2 l/h), but triiodothyronine given together with growth hormone abolished the effect of growth hormone functional hepatic nitrogen clearance (38.8 +/- 4.8 l/h).	Nitrogen	204-212	growth hormone 1	Homo sapiens	170-184
8778198-12	1996	Triiodothyronine has no effect on functional hepatic nitrogen clearance, but given together with growth hormone, it abolishes the effect of growth hormone on functional hepatic nitrogen clearance.	Nitrogen	177-185	growth hormone 1	Homo sapiens	140-154
8778198-11	1996	CONCLUSIONS: The results show that long-term growth hormone administration acts on liver by decreasing functional hepatic nitrogen clearance, thereby retaining amino-N in the body.	Nitrogen	122-130	growth hormone 1	Homo sapiens	45-59
8907587-6	1996	Five experimental compounds CGP-28238, Dup-697, NS-398, SC-58125 and L-745,337, have a greater selectivity for Cox-2.	Nitrogen	48-50	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	111-116
8635486-0	1996	Stimulatory effect of PDGF on HMG-CoA reductase activity and N-linked glycosylation contributes to increased expression of IGF-1 receptors in human fibroblasts.	Nitrogen	61-62	insulin like growth factor 1	Homo sapiens	123-128
8561324-8	1996	The main reason for improved nitrogen economy may be clonidine-induced growth hormone (GH) release.	Nitrogen	29-37	growth hormone 1	Homo sapiens	71-85
8561324-8	1996	The main reason for improved nitrogen economy may be clonidine-induced growth hormone (GH) release.	Nitrogen	29-37	growth hormone 1	Homo sapiens	87-89
8639654-11	1996	These studies highlight the functional importance of the N-glycosylation of the human VIP 1 receptor which belongs to a new subfamily of seven membrane-spanning receptors.	Nitrogen	57-58	vasoactive intestinal peptide	Homo sapiens	86-89
8549861-6	1996	At comparable rates of total nitrogen retention, carcass nitrogen retention was approximately 35% higher with insulin than with IGF treatment, indicating a differential tissue response.	Nitrogen	57-65	insulin	Homo sapiens	110-117
8742227-2	1996	N-Hydroxylation of dapsone in human liver microsomes has been shown to be mediated largely by CYP3A4.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	94-100
8636209-8	1996	In contrast, treatment of T cells with tunicamycin suggested that N-linked glycosylation of CD3 delta is required for TCR assembly.	Nitrogen	66-67	CD3 delta subunit of T-cell receptor complex	Homo sapiens	92-101
8567666-5	1996	In this report, we demonstrate that an N-myristoylated peptide that contains a sequence corresponding to the pseudosubstrate region of PKC-alpha (P1) partially reverses multidrug resistance in MCF7-MDR cells by a novel mechanism that involves inhibition of PKC-alpha.	Nitrogen	39-40	protein kinase C alpha	Homo sapiens	135-144
8551601-2	1996	Sequence analysis of viral DNA derived from long-term cultures of Jurkat cells revealed a specific mutation that changed a highly conserved Asn residue in the V1 loop of Env to an Asp residue (N-136--&gt;D).	Nitrogen	28-29	endogenous retrovirus group W member 1, envelope	Homo sapiens	170-173
8567640-1	1996	The membrane topology of the human Na+/glucose cotransporter SGLT1 has been probed using N-glycosylation scanning mutants and nested truncations.	Nitrogen	35-36	solute carrier family 5 member 1	Homo sapiens	61-66
8567666-5	1996	In this report, we demonstrate that an N-myristoylated peptide that contains a sequence corresponding to the pseudosubstrate region of PKC-alpha (P1) partially reverses multidrug resistance in MCF7-MDR cells by a novel mechanism that involves inhibition of PKC-alpha.	Nitrogen	39-40	protein kinase C alpha	Homo sapiens	257-266
8712396-5	1996	Rates of N-dealkylated metabolite formation significantly correlated with nifedipine oxidation activity (a marker of CYP3A4 activity) for fentanyl and sufentanil (r = 0.93 and 0.87, n = 18, respectively), but not with the oxidation activity for ethoxyresorufin (CYP1A2), S-mephenytoin (CYP2C19), bufuralol (CYP2D6), or chlorzoxazone (CYP2E1).	Nitrogen	9-10	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	117-123
8558528-6	1996	Hydrophilic substituents on the anilino nitrogen abolish agonist activity or produce antagonists of CCK.	Nitrogen	40-48	cholecystokinin	Homo sapiens	100-103
9037790-10	1996	A metabolic alkalosis was present in HLS patients, while, on the other hand, serum nitrogen was significantly higher (p &lt; 0.05), in the first 48 hours after burn, in RLS group.	Nitrogen	83-91	RLS1	Homo sapiens	169-172
8712396-5	1996	Rates of N-dealkylated metabolite formation significantly correlated with nifedipine oxidation activity (a marker of CYP3A4 activity) for fentanyl and sufentanil (r = 0.93 and 0.87, n = 18, respectively), but not with the oxidation activity for ethoxyresorufin (CYP1A2), S-mephenytoin (CYP2C19), bufuralol (CYP2D6), or chlorzoxazone (CYP2E1).	Nitrogen	9-10	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	307-313
8712396-6	1996	Gestodene and troleandomycin (chemical inhibitors of CYP3A4) and antibody to CYP3A4 inhibited N-dealkylation of fentanyl and sufentanil.	Nitrogen	94-95	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	77-83
8712396-8	1996	Recombinant CYP3A4 expressed in Escherichia coli showed N-dealkylation activity of fentanyl and sufentanil, while expressed CYP1A2, 2C10, and 2E1 enzymes did not.	Nitrogen	56-57	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	12-18
8712396-5	1996	Rates of N-dealkylated metabolite formation significantly correlated with nifedipine oxidation activity (a marker of CYP3A4 activity) for fentanyl and sufentanil (r = 0.93 and 0.87, n = 18, respectively), but not with the oxidation activity for ethoxyresorufin (CYP1A2), S-mephenytoin (CYP2C19), bufuralol (CYP2D6), or chlorzoxazone (CYP2E1).	Nitrogen	9-10	cytochrome P450 family 2 subfamily E member 1	Homo sapiens	334-340
8950625-5	1996	Recombinant human growth hormone (rhGH) can preserve or replenish nitrogen reserves, mostly contained in body muscle mass.	Nitrogen	66-74	growth hormone 1	Homo sapiens	18-32
8615602-3	1996	MATERIALS AND METHODS: In this paper, investigation has been made of the correlation between cell surface glycosylation and anti-tumour activity of LAK cells by stimulating peripheral blood lymphocytes with interleukin-2, in the presence of inhibitors of N- and O-glycosylation.	Nitrogen	11-12	interleukin 2	Homo sapiens	207-220
8615602-4	1996	RESULTS: Inhibition of N- or O-glycosylation of proteins during IL-2 activation leads to a 70-80% decrease in the cytolytic activity of LAK cells against K562 and Daudi tumour cells, coinciding with drastic alterations in their cell surface carbohydrate profile.	Nitrogen	23-24	interleukin 2	Homo sapiens	64-68
8964581-1	1996	Corticotropin-releasing hormone-binding protein (CRFBP) is a 37-kD protein of 322 amino acids, containing one putative N-glycosylation site and 11 cysteines, 10 of which remain in the mature molecule (298 amino acids) and result essential for the action.	Nitrogen	119-120	corticotropin releasing hormone binding protein	Homo sapiens	49-54
9383482-2	1995	A 17-residue sequence that includes a cystine disulfide and an N-linked glycosylation site is conserved in the extracellular domain of each of the nAChR subunits, and is involved in intersubunit interactions that are critical for assembly of intact, pentameric complexes.	Nitrogen	63-64	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	147-152
8950359-9	1996	CONCLUSIONS: Oligosaccharides present on PSMA derived from both tissue culture LNCaP cells and in vivo specimens are primarily N-linked and comprise about 20-25% of the native molecular weight.	Nitrogen	2-3	folate hydrolase 1	Homo sapiens	41-45
7592485-3	1995	A second protein encoded by URE2 possesses the genetic characteristics of a negative regulator of nitrogen catabolic gene expression.	Nitrogen	98-106	glutathione peroxidase	Saccharomyces cerevisiae S288C	28-32
8747188-11	1995	VIP induces voltage-dependent inhibition of N-current via a different G protein (Gs) than that of NE (Go).	Nitrogen	44-45	vasoactive intestinal peptide	Rattus norvegicus	0-3
8720070-1	1995	[URE3] is a non-Mendelian genetic element that mimics recessive mutations in the chromosomal URE2 gene making cells derepressed for nitrogen catabolic enzymes.	Nitrogen	132-140	glutathione peroxidase	Saccharomyces cerevisiae S288C	93-97
7592854-3	1995	In contrast, treatment with the proteasomal inhibitor N-acetyl-L-leucyl-L-leucinyl-norleucinal led to a 6-fold accumulation of connexin43 and increased the half-life of connexin43 to approximately 9 h. The role of ubiquitin in connexin43 degradation was examined in an E36-derived mutant, ts20, which contains a thermolabile ubiquitin-activating enzyme, E1.	Nitrogen	54-55	gap junction protein, alpha 1	Mus musculus	169-179
7592854-3	1995	In contrast, treatment with the proteasomal inhibitor N-acetyl-L-leucyl-L-leucinyl-norleucinal led to a 6-fold accumulation of connexin43 and increased the half-life of connexin43 to approximately 9 h. The role of ubiquitin in connexin43 degradation was examined in an E36-derived mutant, ts20, which contains a thermolabile ubiquitin-activating enzyme, E1.	Nitrogen	54-55	ubiquitin	Cricetulus griseus	214-223
7592854-3	1995	In contrast, treatment with the proteasomal inhibitor N-acetyl-L-leucyl-L-leucinyl-norleucinal led to a 6-fold accumulation of connexin43 and increased the half-life of connexin43 to approximately 9 h. The role of ubiquitin in connexin43 degradation was examined in an E36-derived mutant, ts20, which contains a thermolabile ubiquitin-activating enzyme, E1.	Nitrogen	54-55	gap junction protein, alpha 1	Mus musculus	169-179
7592854-3	1995	In contrast, treatment with the proteasomal inhibitor N-acetyl-L-leucyl-L-leucinyl-norleucinal led to a 6-fold accumulation of connexin43 and increased the half-life of connexin43 to approximately 9 h. The role of ubiquitin in connexin43 degradation was examined in an E36-derived mutant, ts20, which contains a thermolabile ubiquitin-activating enzyme, E1.	Nitrogen	54-55	ubiquitin	Cricetulus griseus	325-334
8903720-8	1996	Computer analysis reveals a putative signal peptide and three probable N-glycosylation sites, two of which are also conserved in human PlGF.	Nitrogen	71-72	placental growth factor	Homo sapiens	135-139
7492766-0	1995	Role of antennary structure of N-linked sugar chains in renal handling of recombinant human erythropoietin.	Nitrogen	31-32	erythropoietin	Homo sapiens	92-106
7492766-8	1995	Thus, the well-branched structure of the N-linked sugar chain of EPO is suggested to play an important role in maintaining its higher plasma level, which guarantees an effective transfer to target organs and stimulation of erythroid progenitor cells.	Nitrogen	41-42	erythropoietin	Homo sapiens	65-68
8788208-6	1995	In rat liver, only the N-dealkylation pathway appears to be mediated by CYP3A since anti-rat CYP3A antibody inhibited azacyclonol but not alcohol metabolite formation in incubations of terfenadine with liver microsomes.	Nitrogen	23-24	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	72-77
8788208-6	1995	In rat liver, only the N-dealkylation pathway appears to be mediated by CYP3A since anti-rat CYP3A antibody inhibited azacyclonol but not alcohol metabolite formation in incubations of terfenadine with liver microsomes.	Nitrogen	23-24	cytochrome P450, family 3, subfamily a, polypeptide 62	Rattus norvegicus	93-98
7499420-3	1995	The positions of the four lipophilic domains and the N-glycosylation site of PMP22 are conserved in CL-20, suggesting that it also is an integral membrane glycoprotein.	Nitrogen	53-54	epithelial membrane protein 1	Homo sapiens	100-105
8720143-2	1995	In order to assess the importance of 6-O-sulfate groups in N-sulfated glucosamine (GlcNS) residues to promote FGF-1 and FGF-2 activities, various 6-O-desulfated (6-O-DS-) heparins were quantitatively examined for activity as enhancers or inhibitors of specific FGF-1- and FGF-2-induced proliferation of BALB/c3T3 clone A31 (A31) cells and the chlorate-treated cells.	Nitrogen	59-60	fibroblast growth factor 1	Mus musculus	110-115
8553307-4	1995	METHODS: Plasma levels of endothelin-1 were measured by specific radioimmunoassay in 10 control subjects at rest and following 30 minutes of acute hypoxaemia (SaO2 75-80%) induced by breathing a nitrogen/oxygen mixture, and in 10 patients with hypoxaemic cor pulmonale.	Nitrogen	195-203	endothelin 1	Homo sapiens	26-38
7592854-3	1995	In contrast, treatment with the proteasomal inhibitor N-acetyl-L-leucyl-L-leucinyl-norleucinal led to a 6-fold accumulation of connexin43 and increased the half-life of connexin43 to approximately 9 h. The role of ubiquitin in connexin43 degradation was examined in an E36-derived mutant, ts20, which contains a thermolabile ubiquitin-activating enzyme, E1.	Nitrogen	54-55	gap junction protein, alpha 1	Mus musculus	127-137
7588213-5	1995	Glycosidase digestions indicated that the 25-kDa PRL is N-glycosylated and sialylated, whereas 23-kDa PRL is nonglycosylated.	Nitrogen	56-57	prolactin	Homo sapiens	49-52
8585318-4	1995	The predicted Pmt3p contains 753 amino acids, four potential N-glycosylation sites and it is significantly homologous to Pmt1p, Pmt2p and Pmt4p.	Nitrogen	61-62	dolichyl-phosphate-mannose-protein mannosyltransferase PMT1	Saccharomyces cerevisiae S288C	121-126
7473143-0	1995	N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	51-70
7473143-0	1995	N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors.	Nitrogen	0-1	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	72-77
7490293-2	1995	Anti-Kre2p/Mnt1p antibodies identify a 60-kD integral membrane protein that is progressively N-glycosylated in an MNN1-dependent manner.	Nitrogen	93-94	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	114-118
8585318-4	1995	The predicted Pmt3p contains 753 amino acids, four potential N-glycosylation sites and it is significantly homologous to Pmt1p, Pmt2p and Pmt4p.	Nitrogen	61-62	dolichyl-phosphate-mannose-protein mannosyltransferase PMT2	Saccharomyces cerevisiae S288C	128-133
7569955-1	1995	The genetic properties of the [URE3] non-Mendelian element of Saccharomyces cerevisiae suggest that it is a prion (infectious protein) form of Ure2p, a regulator of nitrogen catabolism.	Nitrogen	165-173	glutathione peroxidase	Saccharomyces cerevisiae S288C	143-148
7589471-0	1995	N-glycosylation-defective receptor for erythropoietin can transduce the ligand-induced cell proliferation signal.	Nitrogen	0-1	erythropoietin	Homo sapiens	39-53
7589471-2	1995	It has been suggested that an erythroleukemia cell line with high sensitivity to EPO expresses a high molecular mass form of EPOR, which appears to be a highly N-glycosylated form responsible for EPO-mediated signal transduction [Sawyer and Hankins (1993) Proc.	Nitrogen	160-161	erythropoietin	Homo sapiens	81-84
7589471-2	1995	It has been suggested that an erythroleukemia cell line with high sensitivity to EPO expresses a high molecular mass form of EPOR, which appears to be a highly N-glycosylated form responsible for EPO-mediated signal transduction [Sawyer and Hankins (1993) Proc.	Nitrogen	160-161	erythropoietin	Homo sapiens	125-128
7590343-9	1995	However, there is an additional potential N-glycosylation site in the turtle sequence and this may provide a better explanation for the greater molecular weight of the turtle protein than chicken RfBP.	Nitrogen	42-43	riboflavin binding protein	Gallus gallus	196-200
7576538-4	1995	Unlike plasma alpha 1AT, however, treatment of the yeast-produced alpha 1AT with endoglycosidase H decreased the molecular mass to that of recombinant alpha 1AT produced in Escherichia coli, indicating the high-mannose type N-linked glycosylation of the secreted alpha 1AT.	Nitrogen	224-225	serpin family A member 1	Homo sapiens	66-75
7576538-4	1995	Unlike plasma alpha 1AT, however, treatment of the yeast-produced alpha 1AT with endoglycosidase H decreased the molecular mass to that of recombinant alpha 1AT produced in Escherichia coli, indicating the high-mannose type N-linked glycosylation of the secreted alpha 1AT.	Nitrogen	224-225	serpin family A member 1	Homo sapiens	66-75
7576538-4	1995	Unlike plasma alpha 1AT, however, treatment of the yeast-produced alpha 1AT with endoglycosidase H decreased the molecular mass to that of recombinant alpha 1AT produced in Escherichia coli, indicating the high-mannose type N-linked glycosylation of the secreted alpha 1AT.	Nitrogen	224-225	serpin family A member 1	Homo sapiens	66-75
7568152-2	1995	Disruption of the chromosomal NIL1 gene enabled us to compare the effects of Gln3p and of Nil1p on the expression of the nitrogen-regulated genes GLN1, GDH2, and GAP1, coding respectively for glutamine synthetase, NAD-linked glutamate dehydrogenase, and general amino acid permease.	Nitrogen	121-129	amino acid permease GAP1	Saccharomyces cerevisiae S288C	162-166
7569955-5	1995	Without this "prion-inducing domain" the carboxyl-terminal domain performed the nitrogen regulation function of Ure2p, but could not be changed to the [URE3] prion state.	Nitrogen	80-88	glutathione peroxidase	Saccharomyces cerevisiae S288C	112-117
8590572-0	1995	Relationships between conformational behaviour and binding affinity towards beta 1 and beta 2 adrenoceptors of some chiral phenoxypropanolamines with bulky N-substituents.	Nitrogen	156-157	potassium calcium-activated channel subfamily M regulatory beta subunit 1	Homo sapiens	76-93
8801862-9	1995	n-LDL reduced the cGMP-levels in unstimulated cells as well as the cGMP increase in response to bradykinin (-10%) and the calcium-ionophore A23187 (-80%).	Nitrogen	0-1	kininogen 1	Homo sapiens	96-106
8556554-4	1995	RESULTS: Der f 7 cDNA encoded a 213 polypeptide containing a predicted 17 amino acid leader sequence, no cysteines and a single N-glycosylation site similar to Der p 7.	Nitrogen	19-20	solute carrier family 10 member 7	Homo sapiens	164-167
7588744-1	1995	UDP-N-acetylglucosamine: alpha-6-D-mannoside beta-1,6-N-acetylglucosaminyltransferase V (GlcNAc transferase V), which catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to alpha-6-D-mannoside, is an important enzyme regulating the branch formation in complex-type, N-linked oligosaccharides.	Nitrogen	4-5	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	54-87
7546769-4	1995	We demonstrated that conditions of anoxia (95% nitrogen/5% CO2) or hyperoxia (95% oxygen/5% CO2) independently resulted in the increased expression of both TNF and MIP-1 alpha mRNA and protein from lipopolysaccharide (LPS)-stimulated AMO, as compared with cells cultured in room air.	Nitrogen	47-55	tumor necrosis factor	Mus musculus	156-159
7547218-0	1995	Plasma chromogranin A marks emesis and serotonin release associated with dacarbazine and nitrogen mustard but not with cyclophosphamide-based chemotherapies.	Nitrogen	89-97	chromogranin A	Homo sapiens	7-21
7547218-7	1995	Plasma CgA and urinary 5-HIAA increased after dacarbazine- and nitrogen mustard-based chemotherapies, with maximal increases between 4 and 6 h after initiation of drug infusion.	Nitrogen	63-71	chromogranin A	Homo sapiens	7-10
7547218-11	1995	In summary, plasma CgA is a marker of serotonin release (most likely from enterochromaffin cells) after dacarbazine and nitrogen mustard-based chemotherapies, exocytosis being the most likely mechanism for the release of serotonin.	Nitrogen	120-128	chromogranin A	Homo sapiens	19-22
8522483-1	1995	The two major topical treatment modalities for cutaneous T-cell lymphoma (CTCL) are mechlorethamine (nitrogen mustard) and topical carmustine (BCNU).	Nitrogen	101-109	TSPY like 2	Homo sapiens	74-78
7665614-15	1995	The extent of il-TMP glycosylation in SW480-glucose cells is similar to that noted in HT-29-glucose cells, lending further support to the notion that il-TMP"s activity is related to its state of N-glycosylation.	Nitrogen	195-196	transmembrane 4 L six family member 4	Homo sapiens	150-156
7496999-11	1995	The greatest increase in N-demethylation activity was observed in the reconstitution system with the lowest concentration of cytochrome P-450 reductase, conditions which most closely resemble intact microsomes.	Nitrogen	25-26	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	125-141
8847710-1	1995	Indirect evidence of the participation of cytochrome P-450 (P-450) in the microsomal N-oxygenation of secondary and tertiary nitrogen functions is presented by studies employing diagnostic modifiers of the hemoprotein system as well as antibodies directed toward the diverse P-450 isoforms and NADPH-cytochrome P-450 reductase.	Nitrogen	85-86	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	42-58
8847710-1	1995	Indirect evidence of the participation of cytochrome P-450 (P-450) in the microsomal N-oxygenation of secondary and tertiary nitrogen functions is presented by studies employing diagnostic modifiers of the hemoprotein system as well as antibodies directed toward the diverse P-450 isoforms and NADPH-cytochrome P-450 reductase.	Nitrogen	85-86	cytochrome p450 oxidoreductase	Homo sapiens	294-326
8847710-1	1995	Indirect evidence of the participation of cytochrome P-450 (P-450) in the microsomal N-oxygenation of secondary and tertiary nitrogen functions is presented by studies employing diagnostic modifiers of the hemoprotein system as well as antibodies directed toward the diverse P-450 isoforms and NADPH-cytochrome P-450 reductase.	Nitrogen	125-133	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	42-58
8847710-1	1995	Indirect evidence of the participation of cytochrome P-450 (P-450) in the microsomal N-oxygenation of secondary and tertiary nitrogen functions is presented by studies employing diagnostic modifiers of the hemoprotein system as well as antibodies directed toward the diverse P-450 isoforms and NADPH-cytochrome P-450 reductase.	Nitrogen	125-133	cytochrome p450 oxidoreductase	Homo sapiens	294-326
8596462-1	1995	When yeast cells growing on a poor nitrogen source are supplied with NH4+ ions, several nitrogen permeases including the general amino acid permease (Gap1p) are rapidly and completely inactivated.	Nitrogen	35-43	amino acid permease GAP1	Saccharomyces cerevisiae S288C	150-155
8596462-1	1995	When yeast cells growing on a poor nitrogen source are supplied with NH4+ ions, several nitrogen permeases including the general amino acid permease (Gap1p) are rapidly and completely inactivated.	Nitrogen	88-96	amino acid permease GAP1	Saccharomyces cerevisiae S288C	150-155
7559420-9	1995	The presence of a nitrogen atom, which is found in many P-glycoprotein substrates and modifiers, is also essential for prenylcysteines to interact with P-glycoprotein.	Nitrogen	18-26	ATP binding cassette subfamily B member 1	Homo sapiens	56-70
7559420-9	1995	The presence of a nitrogen atom, which is found in many P-glycoprotein substrates and modifiers, is also essential for prenylcysteines to interact with P-glycoprotein.	Nitrogen	18-26	ATP binding cassette subfamily B member 1	Homo sapiens	152-166
7665591-1	1995	The contribution of N-linked glycosylation to the ligand binding activity of the rat luteinizing hormone receptor (LHR) was studied in wild-type and mutant LHR expressed in mammalian (COS1) cells and overexpressed in insect (Sf9) cells.	Nitrogen	20-21	luteinizing hormone/choriogonadotropin receptor	Rattus norvegicus	85-113
7562102-7	1995	A negative linear correlation was observed between apparent nitrogen digestibilities of the diets and integrated plasma CCK-LI.	Nitrogen	60-68	cholecystokinin	Felis catus	120-123
7476301-6	1995	The nitrogen-retaining effects of GH seem to involve a direct stimulation of protein synthesis in addition to secondary effects such as generation of insulin-like growth factor-I (IGF-I), hyperinsulinemia, and promotion of lipolysis.	Nitrogen	4-12	growth hormone 1	Homo sapiens	34-36
7476301-6	1995	The nitrogen-retaining effects of GH seem to involve a direct stimulation of protein synthesis in addition to secondary effects such as generation of insulin-like growth factor-I (IGF-I), hyperinsulinemia, and promotion of lipolysis.	Nitrogen	4-12	insulin like growth factor 1	Homo sapiens	150-178
7476301-6	1995	The nitrogen-retaining effects of GH seem to involve a direct stimulation of protein synthesis in addition to secondary effects such as generation of insulin-like growth factor-I (IGF-I), hyperinsulinemia, and promotion of lipolysis.	Nitrogen	4-12	insulin like growth factor 1	Homo sapiens	180-185
7476309-5	1995	It is also certain that GH is a potent anabolic hormone in terms of promoted nitrogen retention, but the extent to which these well-known actions are direct or secondary to hyperinsulinemia, increased activity of insulin-like growth factors (IGFs), or release of protein-conserving lipid intermediates has eluded precise characterization.	Nitrogen	77-85	growth hormone 1	Homo sapiens	24-26
7487423-5	1995	The molecular modelling results suggested that the distances between the basic nitrogen atom and the two aromatic centers (d1 = 5.2-8.4 A, d2 = 5.7-8.5 A, and d3 = 4.6-7.3 A) define the molecular topography of the 5-HT2A receptor antagonists under study.	Nitrogen	79-87	5-hydroxytryptamine receptor 2A	Homo sapiens	214-229
7575653-0	1995	Behavior of N-acylated daunorubicins in MDR1 gene transfected and parental cells.	Nitrogen	12-13	ATP binding cassette subfamily B member 1	Homo sapiens	40-44
8541422-9	1995	CONCLUSIONS: Three days treatment with GH enhanced nitrogen sparing and attenuated changes in fat and carbohydrate oxidation induced by one day treatment, but induced hypertrophy of type I muscle fibres.	Nitrogen	51-59	growth hormone 1	Homo sapiens	39-41
8535396-0	1995	Cytochrome P450 isozymes involved in aromatic hydroxylation and side-chain N-desisopropylation of alprenolol in rat liver microsomes.	Nitrogen	75-76	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-15
12228593-1	1995	Leghemoglobin (Lb) is essential for nitrogen fixation by intact leguminous nodules.	Nitrogen	36-44	leghemoglobin A	Glycine max	0-13
7580763-11	1995	Although further investigation is needed to elucidate the mechanism, the decrease in the incorporation of 15N glycine into fibrinogen suggests alteration in liver nitrogen metabolism at 0.56 MPa.	Nitrogen	163-171	fibrinogen beta chain	Homo sapiens	123-133
7582985-2	1995	The N-unsubstituted, 4-phenethyl derivative 9a demonstrated weak inhibition of these enzymes but acetylation of the beta-lactam N atom afforded 9b, an effective, time-dependent inhibitor of thrombin and a potent inhibitor of plasmin.	Nitrogen	4-5	coagulation factor II, thrombin	Homo sapiens	190-198
7641800-0	1995	Expression of the first N-glycosylation gene in the dolichol pathway, ALG7, is regulated at two major control points in the G1 phase of the Saccharomyces cerevisiae cell cycle.	Nitrogen	24-25	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	70-74
9816057-0	1995	Induction of apoptosis and cell cycle-specific change in expression of p53 in normal lymphocytes and MOLT-4 leukemic cells by nitrogen mustard.	Nitrogen	126-134	tumor protein p53	Homo sapiens	71-74
9816057-5	1995	Exposure of normal lymphocytes to 5 microM nitrogen mustard caused their arrest in G1, an increase in p53 expression which was maximal in such cells, and significant apoptosis in cells located beyond the arrest point (S and G2 + M cells).	Nitrogen	43-51	tumor protein p53	Homo sapiens	102-105
9816057-7	1995	Expression of p53 was highest for S and G2 + M MOLT-4 cells in response to the nitrogen mustard.	Nitrogen	79-87	tumor protein p53	Homo sapiens	14-17
9816057-9	1995	These data suggest that DNA damage caused by nitrogen mustard provides a signal that results in stabilization of wild-type p53, preferentially in G1 cells, causes cell arrest in G1, and induces apoptosis of the cells that either were in the S-phase at the time of drug administration and/or escaped G1 arrest.	Nitrogen	45-53	tumor protein p53	Homo sapiens	123-126
7498764-3	1995	The LPD1 gene product is also required for cells to utilize glycine as sole nitrogen source.	Nitrogen	76-84	dihydrolipoyl dehydrogenase	Saccharomyces cerevisiae S288C	4-8
7641800-1	1995	The Saccharomyces cerevisiae ALG7 gene, which functions by initiating the dolichol pathway of protein N-glycosylation, displays properties of an early growth-response gene.	Nitrogen	102-103	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	29-33
7619827-1	1995	In the presence of a suitable electron acceptor such as mammalian cytochrome c, hydroxylamine oxidoreductase (HAO) from the chemolithotrophic bacterium Nitrosomonas europaea catalyzes the oxidation of hydroxylamine or hydrazine to nitrite or dinitrogen, respectively.	Nitrogen	242-252	cytochrome c, somatic	Homo sapiens	66-78
7615562-7	1995	We have shown that an expression vector coding for an epitope-tagged proIGF-I directs synthesis and secretion of mature IGF-I-(1-70), extended IGF-I-(1-76), proIGF-I, and N-glycosylated proIGF-I in human embryonic kidney 293 cells.	Nitrogen	171-172	insulin like growth factor 1	Homo sapiens	72-77
9373338-5	1995	We now extend these studies and show that the fusion protein, termed IgG3-IL2, is appropriately N-glycosylated within the IgG3 CH2 domain, binds the human high affinity Fc receptor (Fc gamma RI) with an affinity slightly lower than that of IgG3, and is able to activate complement via the classical pathway to lyse antigen coated sheep red blood cells (SRBC).	Nitrogen	96-97	interleukin 2	Homo sapiens	74-77
7631012-8	1995	Our finding that the ATX-70-dependent enhancement of the TMP-NO signal was highest at approximately 20% O2, in both N2/O2 and argon/O2 mixtures, and decreased with increasing oxygen concentration is not compatible with the singlet oxygen mechanism.	Nitrogen	116-118	ectonucleotide pyrophosphatase/phosphodiesterase 2	Homo sapiens	21-24
7544219-1	1995	Insulin-like growth factor I (IGF-I) has been shown experimentally to exert a nitrogen-sparing effect in both animals and humans.	Nitrogen	78-86	insulin like growth factor 1	Homo sapiens	0-28
7628611-3	1995	We report here that the frog KBP has three functional N-glycosylation sites.	Nitrogen	54-55	kinesin family binding protein	Homo sapiens	29-32
7628611-4	1995	Of particular interest, Asn-265, a residue located between two putative membrane spanning regions of the frog KBP, is a functional N-glycosylation site.	Nitrogen	131-132	kinesin family binding protein	Homo sapiens	110-113
7544219-1	1995	Insulin-like growth factor I (IGF-I) has been shown experimentally to exert a nitrogen-sparing effect in both animals and humans.	Nitrogen	78-86	insulin like growth factor 1	Homo sapiens	30-35
7544219-6	1995	urinary nitrogen:creatinine ratio was significantly reduced in patients who received IGF-I compared with those given placebo (275.0(17.1) compared with 386.3(23.6), P &lt; 0.01).	Nitrogen	8-16	insulin like growth factor 1	Homo sapiens	85-90
7544219-7	1995	The mean urinary 3-methylhistidine:creatinine ratio and nitrogen balance were lower in the IGF-I group, but not significantly so.	Nitrogen	56-64	insulin like growth factor 1	Homo sapiens	91-96
7544219-11	1995	The authors conclude that IGF-I does not significantly influence the nitrogen balance, but that results indicate a possible nitrogen-sparing effect in patients after major abdominal operations.	Nitrogen	124-132	insulin like growth factor 1	Homo sapiens	26-31
7772042-7	1995	Thus it is likely that hydrogen-bonding of the enzyme to substituents containing oxygen or nitrogen increases the binding affinity of the hydrazides and enhances their oxidation by myeloperoxidase.	Nitrogen	91-99	myeloperoxidase	Homo sapiens	181-196
7551024-4	1995	When cells of the hex2 mutant were starved for nitrogen on a glucose-containing medium, they rapidly lost viability, similarly to mutants with overactivation of the Ras-adenylate cyclase pathway.	Nitrogen	47-55	protein phosphatase regulator REG1	Saccharomyces cerevisiae S288C	18-22
7551024-7	1995	These results are in agreement with the presence of continuous glucose-triggered activation of cAMP synthesis in hex2 cells on a glucose-containing nitrogen-starvation medium.	Nitrogen	148-156	protein phosphatase regulator REG1	Saccharomyces cerevisiae S288C	113-117
7551024-8	1995	In the course of these experiments a spontaneous suppressor mutant, shx (for suppressor of hex2), was isolated which survived nitrogen starvation on a glucose-containing medium much better than the hex2 strain.	Nitrogen	126-134	protein phosphatase regulator REG1	Saccharomyces cerevisiae S288C	91-95
7551024-11	1995	The isolation of this epistatic depression mutation supports the idea that the defect in glucose repression of the hex2 mutant is the cause of its rapid loss of viability during nitrogen starvation on a glucose-containing medium.	Nitrogen	178-186	protein phosphatase regulator REG1	Saccharomyces cerevisiae S288C	115-119
8948435-6	1995	In contrast, the recombinant C4BP did not bind protein S and therefore did not inhibit the ability of protein S to function as a cofactor to activated protein C. Tunicamycin treatment of the transfected cells prevented N-linked glycosylation, but did not affect polymerization of the alpha-chains into a high-molecular-mass C4BP.	Nitrogen	219-220	complement component 4 binding protein alpha	Homo sapiens	29-33
7779785-6	1995	Treatment of YAP3p with endoglycosidase H reduced the size of both forms of the protein to approximately 65 kDa, consistent with the presence of 10 potential N-linked glycosylation sites in the deduced amino acid sequence of this protein.	Nitrogen	158-159	Yap3p	Saccharomyces cerevisiae S288C	13-18
9634799-0	1995	N-glycosylation of recombinant human interferon-gamma produced in different animal expression systems.	Nitrogen	0-1	interferon gamma	Homo sapiens	37-53
7782289-8	1995	In each case, an N-glycosylated 27-kDa protein was generated, that, like TIMP-1 and TIMP-2, inhibited collagenase-1, stromelysin-1, and gelatinases A and B.	Nitrogen	17-18	tissue inhibitor of metalloproteinase 1	Mus musculus	73-79
7540941-4	1995	The data from both models established that TNF alpha and the 55 kDa TNF receptor are essential for protection against tuberculosis in mice, and for reactive nitrogen production by macrophages early in infection.	Nitrogen	157-165	tumor necrosis factor	Mus musculus	43-52
7673075-8	1995	Nitrogen supplementation increased (P &lt; .01) blood urea nitrogen and apparent absorption and retention of N. Results indicate that S fertilization enhanced forage quality primarily due to increased TNC concentration, digestibility of hemicellulose, and N utilization by lambs but could exacerbate Cu deficiency where Cu levels are marginal.	Nitrogen	0-8	tenascin	Ovis aries	201-204
7628865-1	1995	Poly(ADPR) polymerase (PARP; EC 2.4.2.30) is a nuclear enzyme, which, when activated by oxygen- and nitrogen-radical-induced DNA strand breaks, transfers ADP ribose units to nuclear proteins and initiates apoptosis by depletion of cellular NAD and ATP pools.	Nitrogen	100-108	poly(ADP-ribose) polymerase 1	Homo sapiens	23-27
7538287-5	1995	Tumor necrosis factor (0.1-2 ng/mL) increased System y(+)-mediated arginine transport in a time- and dose-dependent manner by augmenting System y+ transport maximal capacity (control Vmax = 1325 +/- 60 pmol/mg protein/minute vs. TNF Vmax = 3015 +/- 110 pmol/mg protein/minute, p &lt; 0.01) without affecting transporter affinity (control Km = 30 +/- 1.4 microM vs. 34 +/- 1.3 microM arginine, p = NS).	Nitrogen	397-399	tumor necrosis factor	Homo sapiens	0-21
7572320-0	1995	Interleukin-6 and the acute phase response during treatment of patients with Paget"s disease with the nitrogen-containing bisphosphonate dimethylaminohydroxypropylidene bisphosphonate.	Nitrogen	102-110	interleukin 6	Homo sapiens	0-13
7663166-6	1995	N-Glycanase digestion resulted in the same mobility shift of OSF-2, indicating that rmOSF-2 expressed in insect cells is N-glycosylated.	Nitrogen	0-1	periostin, osteoblast specific factor	Mus musculus	61-66
7755594-10	1995	Whether the differential glycosylation of n- and recombinant IFN-gamma (rIFN-gamma) is reflected in their biological activities in tissues or their clinical applicability is not known.	Nitrogen	19-20	interferon gamma	Homo sapiens	61-70
7744762-2	1995	O-Sulfation at C-3 of N-sulfated GlcN units concludes polymer modification and the formation of antithrombin binding regions in the biosynthesis of heparin/heparan sulfate.	Nitrogen	22-23	serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1	Mus musculus	96-108
7766663-1	1995	Activation of glycogen synthase (GS) by insulin in isolated, aerated muscle was abolished when oxygen was replaced by nitrogen.	Nitrogen	118-126	insulin	Homo sapiens	40-47
7766663-2	1995	Reoxygenation of the muscle after prior exposure to nitrogen restored the insulin effect.	Nitrogen	52-60	insulin	Homo sapiens	74-81
7755594-0	1995	N-glycosylation of human interferon-gamma: glycans at Asn-25 are critical for protease resistance.	Nitrogen	0-1	interferon gamma	Homo sapiens	25-41
7755594-1	1995	Human interferon-gamma (IFN-gamma) is a secretory, dimeric glycoprotein that forms a compact globular structure with potential N-linked glycosylation sites at Asn-25 and Asn-97 on the surface of the dimer.	Nitrogen	26-27	interferon gamma	Homo sapiens	6-22
7733029-4	1995	With and without clamping, respectively, insulin reduced nitrogen (22.1 and 48.2 mg.kg-1.9 h-1, P &lt; 0.01) and urea (15.8 and 37.5 mg.kg-1.9 h-1, P &lt; 0.05) but increased ammonia (7.7 and 5.0 mg.kg-1.9 h-1, P &lt; 0.05) excretion.	Nitrogen	57-65	insulin	Homo sapiens	41-48
7741300-17	1995	Rate constants were 1.46 x 10(-9) ppm-2.min-1 when NO was mixed with N2, 1.17 x 10(-8) ppm-2.min-1 when NO was blended with air, and 1.44 x 10(-9) ppm-2.min-1 in the test lung.	Nitrogen	69-71	leucine carboxyl methyltransferase 2	Homo sapiens	34-39
7741300-17	1995	Rate constants were 1.46 x 10(-9) ppm-2.min-1 when NO was mixed with N2, 1.17 x 10(-8) ppm-2.min-1 when NO was blended with air, and 1.44 x 10(-9) ppm-2.min-1 in the test lung.	Nitrogen	69-71	CD59 molecule (CD59 blood group)	Homo sapiens	40-45
7733657-14	1995	The activity and protein levels of cAspAT and mAspAT selectively increased during recovery from an nitrogen deficit, primarily as a consequence of increase in the levels of their mRNAs while those of pAspAT remained unchanged.	Nitrogen	99-107	glutamatic-oxaloacetic transaminase 2, mitochondrial	Mus musculus	46-52
7790317-0	1995	Increased susceptibility to N-nitrosomethylurea gastric carcinogenesis in transforming growth factor alpha transgenic mice with gastric hyperplasia.	Nitrogen	28-29	tumor necrosis factor	Homo sapiens	74-106
7715705-4	1995	Here we report a synergistic effect between A beta and interferon-gamma (IFN-gamma) in triggering the production of reactive nitrogen intermediates and tumour-necrosis factor-alpha (TNF-alpha) from microglia.	Nitrogen	125-133	amyloid beta precursor protein	Homo sapiens	44-50
7721869-0	1995	The role of N-glycosylation in the targeting and activity of the GLYT1 glycine transporter.	Nitrogen	12-13	solute carrier family 6 member 9	Homo sapiens	65-70
7721869-1	1995	To elucidate the role of N-glycosylation in the function of the high affinity glycine transporter GLYT1, we have investigated the effect of the glycosylation inhibitor tunicamycin as well as the effect of the disruption of the putative glycosylation sites by site-directed mutagenesis.	Nitrogen	25-26	solute carrier family 6 member 9	Homo sapiens	98-103
7721869-6	1995	N-Glycosylation of the GLYT1 is not indispensable for the transport activity itself, as demonstrated by enzymatic deglycosylation of the transporter.	Nitrogen	0-1	solute carrier family 6 member 9	Homo sapiens	23-28
7712474-1	1995	The N-linked sugar chain structures of the carcinoembryonic antigen (CEA) produced by liver metastases of colon cancers and the normal counterpart of CEA purified from human adult feces (NFA-2) were previously determined comparatively (K. Fukushima, T. Ohkura, M. Kanai, M. Kuroki, Y. Matsuoka, A. Kobata, and K. Yamashita.	Nitrogen	4-5	CEA cell adhesion molecule 3	Homo sapiens	43-67
7712474-1	1995	The N-linked sugar chain structures of the carcinoembryonic antigen (CEA) produced by liver metastases of colon cancers and the normal counterpart of CEA purified from human adult feces (NFA-2) were previously determined comparatively (K. Fukushima, T. Ohkura, M. Kanai, M. Kuroki, Y. Matsuoka, A. Kobata, and K. Yamashita.	Nitrogen	4-5	CEA cell adhesion molecule 3	Homo sapiens	69-72
7715705-4	1995	Here we report a synergistic effect between A beta and interferon-gamma (IFN-gamma) in triggering the production of reactive nitrogen intermediates and tumour-necrosis factor-alpha (TNF-alpha) from microglia.	Nitrogen	125-133	interferon gamma	Homo sapiens	55-71
7715705-4	1995	Here we report a synergistic effect between A beta and interferon-gamma (IFN-gamma) in triggering the production of reactive nitrogen intermediates and tumour-necrosis factor-alpha (TNF-alpha) from microglia.	Nitrogen	125-133	interferon gamma	Homo sapiens	73-82
7715705-6	1995	These findings suggest that A beta and IFN-gamma activate microglia to produce reactive nitrogen intermediates and TNF-alpha, and this may have a role in the pathogenesis of neuronal degeneration observed in ageing and Alzheimer"s disease.	Nitrogen	88-96	amyloid beta precursor protein	Homo sapiens	28-34
7715705-6	1995	These findings suggest that A beta and IFN-gamma activate microglia to produce reactive nitrogen intermediates and TNF-alpha, and this may have a role in the pathogenesis of neuronal degeneration observed in ageing and Alzheimer"s disease.	Nitrogen	88-96	interferon gamma	Homo sapiens	39-48
7640150-2	1995	Studies using human liver microsomes and six recombinant human CYP isoforms (i.e. CYP1A2, 2A6, 2B6, 2D6, 2E1 and 3A4) were performed to identify the cytochrome P450 (CYP) isoform(s) involved in the ring 4-hydroxylation and side-chain N-desisopropylation of propranolol enantiomers in humans.	Nitrogen	234-235	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	149-164
7710927-0	1995	Inhibition of N-linked glycosylation of P-glycoprotein by tunicamycin results in a reduced multidrug resistance phenotype.	Nitrogen	14-15	ATP binding cassette subfamily B member 1	Homo sapiens	40-54
7592547-6	1995	We found that the yield of the beta form of the Asn137-to-Ala mutant (designated as sTF beta NNA) was threefold higher (3 mg/liter) than that of the wild type, suggesting that the replacement of one of the three potential N-glycosylation Asn residues with Ala could be a good way to minimize the addition of mannose repeats.	Nitrogen	93-94	cystatin B	Homo sapiens	84-92
16843907-5	1995	A correlation between insulin levels and nitrogen balance was found only in DP-Gln 20 treated patients day 6 (r = 0.91, p &lt; 0.01).	Nitrogen	41-49	insulin	Homo sapiens	22-29
7712756-11	1995	Nitrogen balance differed between the groups upon admission: growth hormone group (3.9 +/- 4.1 g/day) vs. controls (13.8 +/- 5.4 g/day), but improved with growth hormone.	Nitrogen	0-8	growth hormone 1	Homo sapiens	61-75
7712756-11	1995	Nitrogen balance differed between the groups upon admission: growth hormone group (3.9 +/- 4.1 g/day) vs. controls (13.8 +/- 5.4 g/day), but improved with growth hormone.	Nitrogen	0-8	growth hormone 1	Homo sapiens	155-169
7712756-19	1995	Hence, growth hormone affects nitrogen balance, probably partly independent of insulin-like growth factor I.	Nitrogen	30-38	growth hormone 1	Homo sapiens	7-21
24394272-7	1995	The anabolic action of GH was first demonstrated when nitrogen retention was observed after GH administration.	Nitrogen	54-62	growth hormone 1	Homo sapiens	23-25
7876253-6	1995	This demonstrated that folding and disulfide bond formation of t-PA determines its extent of core N-linked glycosylation.	Nitrogen	98-99	plasminogen activator, tissue type	Homo sapiens	63-67
7891726-3	1995	The products of the GLN3 and URE2 genes are required for the appropriate transcription of many genes in alternative nitrogen assimilatory pathways.	Nitrogen	116-124	glutathione peroxidase	Saccharomyces cerevisiae S288C	29-33
7891726-4	1995	GLN3 appears to activate their transcription when good nitrogen sources are unavailable, and URE2 appears to repress their transcription when alternative nitrogen sources are not needed.	Nitrogen	154-162	glutathione peroxidase	Saccharomyces cerevisiae S288C	93-97
7891726-6	1995	Comparison of PUT gene expression in cells grown in repressing or derepressing nitrogen sources, in the absence of the inducer proline, indicated that both PUT1 and PUT2 are regulated by nitrogen repression, although the effect on PUT2 is comparatively small.	Nitrogen	187-195	proline dehydrogenase	Saccharomyces cerevisiae S288C	156-160
7891726-7	1995	Recessive mutations in URE2 elevated expression of the PUT1 and PUT2 genes 5- to 10-fold when cells were grown on a nitrogen-repressing medium.	Nitrogen	116-124	glutathione peroxidase	Saccharomyces cerevisiae S288C	23-27
7891726-7	1995	Recessive mutations in URE2 elevated expression of the PUT1 and PUT2 genes 5- to 10-fold when cells were grown on a nitrogen-repressing medium.	Nitrogen	116-124	proline dehydrogenase	Saccharomyces cerevisiae S288C	55-59
7891726-12	1995	URE2 repression appears to be limited to nitrogen assimilatory systems and does not affect genes involved in carbon, inositol, or phosphate metabolism or in mating-type control and sporulation.	Nitrogen	41-49	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-4
7700231-2	1995	In deletion experiments a sequence located between positions -644 and -591 was found to be responsible for transcriptional repression of the CPS1 gene in yeast cells grown on rich nitrogen sources.	Nitrogen	180-188	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	141-145
7700231-6	1995	In addition, at least three other upstream activation UASs responsible for the activation of CPS1 expression by glucose under nitrogen starvation conditions were found to be located between positions -673 and -644, -482 and -353, and -243 and -186, respectively.	Nitrogen	126-134	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	93-97
7700231-7	1995	The putative mechanism of the nitrogen limitation-dependent regulation of CPS1 expression via these regulatory elements is discussed.	Nitrogen	30-38	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	74-78
24394272-7	1995	The anabolic action of GH was first demonstrated when nitrogen retention was observed after GH administration.	Nitrogen	54-62	growth hormone 1	Homo sapiens	92-94
7532677-9	1995	Asparagine 86, the single site of N-linked glycosylation on class I molecules, is in close proximity to the Bw4/Bw6 region.	Nitrogen	34-35	BW4	Homo sapiens	108-111
7858253-0	1995	N- and O-glycosylation muteins of recombinant human erythropoietin secreted from BHK-21 cells.	Nitrogen	0-1	erythropoietin	Homo sapiens	52-66
7609279-5	1995	RESULTS: Hypoaminoacidemia of trauma is normalized by infusion of recombinant human growth hormone, which indicates its anabolic nature, and this is confirmed in the cumulative nitrogen balance (-281 +/- 139 mg of nitrogen per kilogram per 7 days compared with -809 +/- 151 mg of nitrogen per kilogram per 7 days without recombinant human growth hormone; p &lt; or = .005).	Nitrogen	177-185	growth hormone 1	Homo sapiens	84-98
7775978-2	1995	Potentiometric and spectroscopic (absorption, circular dichroism and electron paramagnetic resonance) study on the coordination of two angiotensin II fragments (Asp-Arg-Val-Tyr-Ile-His and Arg-Val-Tyr-Ile-His) to Cu(II) ions has shown that competition between amino and imidazole nitrogens to anchor metal ions is a complicated process and may lead to formation of macrochelate rings.	Nitrogen	280-289	angiotensinogen	Homo sapiens	135-149
7609279-5	1995	RESULTS: Hypoaminoacidemia of trauma is normalized by infusion of recombinant human growth hormone, which indicates its anabolic nature, and this is confirmed in the cumulative nitrogen balance (-281 +/- 139 mg of nitrogen per kilogram per 7 days compared with -809 +/- 151 mg of nitrogen per kilogram per 7 days without recombinant human growth hormone; p &lt; or = .005).	Nitrogen	214-222	growth hormone 1	Homo sapiens	84-98
7609279-5	1995	RESULTS: Hypoaminoacidemia of trauma is normalized by infusion of recombinant human growth hormone, which indicates its anabolic nature, and this is confirmed in the cumulative nitrogen balance (-281 +/- 139 mg of nitrogen per kilogram per 7 days compared with -809 +/- 151 mg of nitrogen per kilogram per 7 days without recombinant human growth hormone; p &lt; or = .005).	Nitrogen	214-222	growth hormone 1	Homo sapiens	84-98
7609279-6	1995	This improved nitrogen retention is also reflected in the significantly low blood urea nitrogen levels in the recombinant human growth hormone group, which represents the efficient utilization of the infused amino acids for synthesis of proteins.	Nitrogen	14-22	growth hormone 1	Homo sapiens	128-142
7885022-8	1995	Recombinant human insulin-like growth factor-1 significantly improved nitrogen balance without compromising hepatic response as measured by liver fractional synthetic rate, cytochrome P450 concentration, and ECOD activity in endotoxemic parenterally fed rats.	Nitrogen	70-78	insulin like growth factor 1	Homo sapiens	18-46
7609279-6	1995	This improved nitrogen retention is also reflected in the significantly low blood urea nitrogen levels in the recombinant human growth hormone group, which represents the efficient utilization of the infused amino acids for synthesis of proteins.	Nitrogen	87-95	growth hormone 1	Homo sapiens	128-142
7609279-8	1995	CONCLUSIONS: Recombinant human growth hormone treatment in combination with conventional total parenteral nutrition in the immediate posttraumatic period improved nitrogen metabolism and normalized the plasma free amino acid levels.	Nitrogen	163-171	growth hormone 1	Homo sapiens	31-45
7873591-1	1995	The enzyme which initiates the dolichol pathway of protein N-glycosylation, dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT), is encoded by the ALG7 gene.	Nitrogen	59-60	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	158-162
7873591-3	1995	ALG7 is an early growth-response gene in yeast, and downregulation of ALG7 expression results in diminished N-glycosylation and secretion of Xenopus oocyte proteins.	Nitrogen	108-109	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	70-74
7852368-2	1995	Myeloperoxidase and eosinophil peroxidase catalyzed the oxidation of bromide ion by hydrogen peroxide (H2O2) and produced a brominating agent that reacted with amine compounds to form bromamines, which are long-lived oxidants containing covalent nitrogen-bromine bonds.	Nitrogen	246-254	myeloperoxidase	Homo sapiens	0-15
7873591-1	1995	The enzyme which initiates the dolichol pathway of protein N-glycosylation, dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT), is encoded by the ALG7 gene.	Nitrogen	97-98	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	158-162
7852368-2	1995	Myeloperoxidase and eosinophil peroxidase catalyzed the oxidation of bromide ion by hydrogen peroxide (H2O2) and produced a brominating agent that reacted with amine compounds to form bromamines, which are long-lived oxidants containing covalent nitrogen-bromine bonds.	Nitrogen	246-254	eosinophil peroxidase	Homo sapiens	20-41
7873591-3	1995	ALG7 is an early growth-response gene in yeast, and downregulation of ALG7 expression results in diminished N-glycosylation and secretion of Xenopus oocyte proteins.	Nitrogen	108-109	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	0-4
7766851-5	1995	Results indicate that the C=N bond of PBN is cleaved by A beta in what we hypothesize is a radical addition-fragmentation reaction.	Nitrogen	28-29	amyloid beta precursor protein	Homo sapiens	56-62
7867791-0	1995	"Brain-type" N-glycosylation of asialo-transferrin from human cerebrospinal fluid.	Nitrogen	13-14	transferrin	Homo sapiens	39-50
7778765-7	1995	Then, the microsomal N-hydroxylation activity on Trp-P-2 was compared with five different sources of microsomes.	Nitrogen	21-22	polycystin 2, transient receptor potential cation channel	Rattus norvegicus	49-56
7857222-0	1995	The effect of recombinant growth hormone on nitrogen balance in malnourished patients after major abdominal surgery.	Nitrogen	44-52	growth hormone 1	Homo sapiens	26-40
7847429-7	1995	Growth hormone also caused nitrogen sparing, and the mean daily nitrogen balance was significantly greater during the injections (growth hormone 36.9 +/- 121.1 mmol/day; diet alone -122.3 +/- 125.9 mmol/day; P &lt; 0.001).	Nitrogen	27-35	growth hormone 1	Homo sapiens	0-14
7847429-8	1995	This nitrogen-sparing response to growth hormone attenuated over the 4 weeks of the injections.	Nitrogen	5-13	growth hormone 1	Homo sapiens	34-48
7857222-1	1995	The effect of recombinant growth hormone (rGH) on nitrogen balance was studied in malnourished patients receiving total parenteral nutrition after major abdominal surgery.	Nitrogen	50-58	growth hormone 1	Homo sapiens	26-40
7870042-5	1995	The cGMP-inhibited PDE (cGI-PDE, PDE3) may interact less strongly with this nitrogen.	Nitrogen	76-84	phosphodiesterase 3A	Homo sapiens	4-22
7772858-7	1995	NFA-2 contains 24-27 mol of N-linked sugar chains/molecule, which is similar to NCA-2 (27 mol) and CEA (24-27 mol).	Nitrogen	0-1	CEA cell adhesion molecule 3	Homo sapiens	99-102
7870042-5	1995	The cGMP-inhibited PDE (cGI-PDE, PDE3) may interact less strongly with this nitrogen.	Nitrogen	76-84	phosphodiesterase 3A	Homo sapiens	24-31
7832763-8	1995	Both NS-398 and Dup-697 exhibited time-dependent inactivation of hCOX-2, as did indomethacin on both enzymes.	Nitrogen	5-7	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	65-71
7749652-10	1995	These results suggest that various forms of P450 are involved in TMO metabolism to some extent and that CYP2E1 is attributed to major P450 isozyme for TMO N-demethylation in vivo.	Nitrogen	155-156	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	104-110
7827090-8	1995	In both the rhodopsin and bathorhodopsin models, we have included a structural water molecule hydrogen bonded with the Schiff base to account for the high C = N stretching vibrations previously observed.	Nitrogen	159-160	rhodopsin	Homo sapiens	12-21
7832797-2	1995	In the present report we investigated the effect of tunicamycin, a specific inhibitor of N-linked glycosylation, on the expression and function of the thrombin receptor on human T-lymphoblastoid cells.	Nitrogen	89-90	coagulation factor II, thrombin	Homo sapiens	151-159
7832797-5	1995	These findings indicate a role for N-linked glycosylation in the surface expression of the thrombin receptor in T lymphoid cells.	Nitrogen	35-36	coagulation factor II, thrombin	Homo sapiens	91-99
7792749-0	1995	Antithrombotic effect of a recombinant von Willebrand factor, VCL, on nitrogen laser-induced thrombus formation in guinea pig mesenteric arteries.	Nitrogen	70-78	vinculin	Cavia porcellus	62-65
7755894-2	1995	The striatal induction of c-fos and junB mRNA and Fos protein was blocked by naloxone, the D1 dopamine (DA) receptor antagonists, SCH23390 and SCH39166, and the N-methyl-D-aspartate (NMDA) glutamate receptor antagonist, MK801.	Nitrogen	43-44	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	36-40
7798155-1	1995	The cellular level and activity of the general amino acid permease, the product of the GAP1 gene of Saccharomyces cerevisiae, are regulated at the level of transcription by two systems, the products of URE2/GLN3 and NIL1 in response to the nitrogen sources of the growth medium and inactivation in response to the presence of glutamine or glutamate.	Nitrogen	240-248	amino acid permease GAP1	Saccharomyces cerevisiae S288C	87-91
7756104-6	1995	The immunoidentified CYP2D6 and CYP3A4 correlated with the rates of O-deethylation (r = 0.972) and N-demethylation (r = 0.969), respectively.	Nitrogen	99-100	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	21-27
7756104-6	1995	The immunoidentified CYP2D6 and CYP3A4 correlated with the rates of O-deethylation (r = 0.972) and N-demethylation (r = 0.969), respectively.	Nitrogen	99-100	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	32-38
7810534-8	1995	In PNS rats, plasma AVP was significantly higher than in control rats (control 0.77 +/- 0.10 pg/mL v PNS 2.13 +/- 0.42 pg/mL; P &lt; 0.005, n = 12), even though there were no differences in plasma osmolality (control 292.0 +/- 2.0 mOsm/kg H2O v PNS 290.3 +/- 2.5 mOsm/kg H2O; P = NS, n = 12) or serum sodium concentration (control 142.7 +/- 0.7 v PNS 142.1 +/- 1.1; PNS, n = 12).	Nitrogen	4-6	arginine vasopressin	Rattus norvegicus	20-23
7486340-10	1995	The rGH potentiates nitrogen sparing effect of IGF-1 and decreases hypoglycaemia induced by IGF-1.	Nitrogen	20-28	insulin like growth factor 1	Homo sapiens	47-52
7654131-7	1995	CYP3A enzymes are principally responsible for the cocaine N-demethylation in human and mouse liver microsomes.	Nitrogen	58-59	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	0-5
7538170-0	1995	Resistance of nitrogen metabolism to growth hormone treatment in the early phase after injury of patients with multiple injuries.	Nitrogen	14-22	growth hormone 1	Homo sapiens	37-51
7658599-1	1995	BACKGROUND: Earlier clinical studies have demonstrated improved nitrogen balance in nonstressed patients receiving hypocaloric feedings and growth hormone (GH).	Nitrogen	64-72	growth hormone 1	Homo sapiens	140-154
7658599-1	1995	BACKGROUND: Earlier clinical studies have demonstrated improved nitrogen balance in nonstressed patients receiving hypocaloric feedings and growth hormone (GH).	Nitrogen	64-72	growth hormone 1	Homo sapiens	156-158
7700733-2	1995	A 1-h exposure at 37 degrees C to a 1.7 mM bolus dose of NO, prepared in N2-gassed medium, significantly reduced clonogenic survival in the HA1 fibroblasts line to 60% of control cells treated with N2-gassed medium alone.	Nitrogen	73-75	Rho GTPase activating protein 45	Homo sapiens	140-143
7829600-8	1995	GH administration caused a significant increase in nitrogen balance (from -0.12 +/- 0.04 to -0.03 +/- 0.02 g/kg.day; P &lt; 0.05), osteocalcin, carboxy-terminal propeptide of type I procollagen, and carboxy-terminal telopeptide of type I collagen with respect to basal levels.	Nitrogen	51-59	growth hormone 1	Homo sapiens	0-2
7798155-1	1995	The cellular level and activity of the general amino acid permease, the product of the GAP1 gene of Saccharomyces cerevisiae, are regulated at the level of transcription by two systems, the products of URE2/GLN3 and NIL1 in response to the nitrogen sources of the growth medium and inactivation in response to the presence of glutamine or glutamate.	Nitrogen	240-248	glutathione peroxidase	Saccharomyces cerevisiae S288C	202-206
7696209-4	1994	At 1 microM, both N-formylated and unformylated ND1 peptides induced equivalent levels of killing.	Nitrogen	18-19	NADH dehydrogenase 1, mitochondrial	Mus musculus	48-51
9383395-6	1994	Using X-ray diffraction analysis, we determined that the amide nitrogens of the aziridine rings have tetrahedral sp3-like geometry with tilt angles in the range of 37-38 degrees.	Nitrogen	63-72	Sp3 transcription factor	Homo sapiens	113-116
7854012-4	1994	Bleeding times increased after birth from 4-6 min to 7-10 min by week 4 (P &lt; 0.001), and were higher in pigs fed diets containing 18:3n-3, as well as in sow-reared piglets receiving n-3 polyunsaturated fatty acids (PUFA) in the milk, as compared to diets low in 18:3n-3.	Nitrogen	6-7	Polyunsaturated fatty acid percentage	Sus scrofa	189-216
8002570-0	1994	The URE2 protein regulates nitrogen catabolic gene expression through the GATAA-containing UASNTR element in Saccharomyces cerevisiae.	Nitrogen	27-35	glutathione peroxidase	Saccharomyces cerevisiae S288C	4-8
8002570-4	1994	The expression of these nitrogen catabolic genes becomes, to various degrees, NCR insensitive in the ure2 deletion.	Nitrogen	24-32	glutathione peroxidase	Saccharomyces cerevisiae S288C	101-105
8002570-6	1994	The various responses of the nitrogen catabolic genes" expression to deletion of the URE2 locus also indicate that not all NCR is mediated through URE2.	Nitrogen	29-37	glutathione peroxidase	Saccharomyces cerevisiae S288C	85-89
7846154-6	1994	We also investigated whether light-induced changes in nitrogen to carbon ratios might exert a metabolic regulation of the ASN1 mRNA accumulation.	Nitrogen	54-62	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	122-126
7704038-3	1994	The kinetic parameters for the N-demethylation in the EM group were: Km 1, 19.4 +/- 0.4 microM; Vmax 1, 0.27 +/- 0.04 nmol min-1 per mg protein; Km 2, 346 +/- 34 microM; Vmax2, 1.82 +/- 0.63 nmol min-1 per mg protein (n = 3, mean +/- SD).	Nitrogen	31-32	CD59 molecule (CD59 blood group)	Homo sapiens	123-128
7846154-9	1994	These findings suggest that the expression of the ASN1 gene is under the metabolic control of the nitrogen to carbon ratio in cells.	Nitrogen	98-106	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	50-54
7704038-3	1994	The kinetic parameters for the N-demethylation in the EM group were: Km 1, 19.4 +/- 0.4 microM; Vmax 1, 0.27 +/- 0.04 nmol min-1 per mg protein; Km 2, 346 +/- 34 microM; Vmax2, 1.82 +/- 0.63 nmol min-1 per mg protein (n = 3, mean +/- SD).	Nitrogen	31-32	CD59 molecule (CD59 blood group)	Homo sapiens	196-201
7846154-10	1994	This is consistent with the fact that asparagine, synthesized by the ASN1 gene product, is a favored compound for nitrogen storage and nitrogen transport in dark-grown plants.	Nitrogen	114-122	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	69-73
7846154-10	1994	This is consistent with the fact that asparagine, synthesized by the ASN1 gene product, is a favored compound for nitrogen storage and nitrogen transport in dark-grown plants.	Nitrogen	135-143	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	69-73
7846154-11	1994	We have put forth a working model suggesting that when nitrogen to carbon ratios are high, the gene product of ASN1 functions to re-direct the flow of nitrogen into asparagine, which acts as a shunt for storage and/or long-distance transport of nitrogen.	Nitrogen	55-63	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	111-115
7846154-11	1994	We have put forth a working model suggesting that when nitrogen to carbon ratios are high, the gene product of ASN1 functions to re-direct the flow of nitrogen into asparagine, which acts as a shunt for storage and/or long-distance transport of nitrogen.	Nitrogen	151-159	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	111-115
7846154-11	1994	We have put forth a working model suggesting that when nitrogen to carbon ratios are high, the gene product of ASN1 functions to re-direct the flow of nitrogen into asparagine, which acts as a shunt for storage and/or long-distance transport of nitrogen.	Nitrogen	151-159	glutamine-dependent asparagine synthase 1	Arabidopsis thaliana	111-115
7832523-0	1994	Cell aggregation in a Chinese hamster ovary cell microcarrier culture affects the expression rate and N-linked glycosylation of recombinant mouse placental lactogen-1.	Nitrogen	102-103	prolactin family 3, subfamily d, member 1	Mus musculus	146-166
7886321-4	1994	In critically ill patients, the administration of recombinant human GH improves nitrogen and mineral retention, enhances protein synthesis, and reduces urea generation.	Nitrogen	80-88	growth hormone 1	Homo sapiens	68-70
7832523-1	1994	A microcarrier culture of Chinese hamster ovary (CHO) cells, expressing the N-glycosylated recombinant protein mouse placental lactogen I (mPL-I), was found to form large cellular aggregates (400 to 600 microns in diameter).	Nitrogen	76-77	prolactin family 3, subfamily d, member 1	Mus musculus	117-137
7832523-1	1994	A microcarrier culture of Chinese hamster ovary (CHO) cells, expressing the N-glycosylated recombinant protein mouse placental lactogen I (mPL-I), was found to form large cellular aggregates (400 to 600 microns in diameter).	Nitrogen	76-77	prolactin family 3, subfamily d, member 1	Mus musculus	139-144
7954409-8	1994	We also observed an inverse sensitivity relationship between nitrogen mustard/cisplatin and etoposide in the mutant p53 lines and this was found to correlate with topoisomerase II mRNA levels in the cells.	Nitrogen	61-69	tumor protein p53	Homo sapiens	116-119
7808401-0	1994	DNA binding site specificity of the Neurospora global nitrogen regulatory protein NIT2: analysis with mutated binding sites.	Nitrogen	54-62	putative hydrolase	Saccharomyces cerevisiae S288C	82-86
7895609-3	1994	We characterized cytochrome P450 isozymes responsible for propranolol metabolism, especially N-desisopropylation and 5-hydroxylation, in human liver microsomes.	Nitrogen	93-94	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	17-32
7808401-1	1994	NIT2, a positive-acting regulatory protein in Neurospora crassa, activates the expression of a series of unlinked structural genes that encode nitrogen catabolic enzymes.	Nitrogen	143-151	putative hydrolase	Saccharomyces cerevisiae S288C	0-4
7980452-0	1994	Role of N-glycosylation in the synthesis, dimerization and secretion of human interferon-gamma.	Nitrogen	8-9	interferon gamma	Homo sapiens	78-94
7980452-1	1994	Human interferon-gamma (IFN-gamma) is a secretory glycoprotein, which has two potential N-linked glycosylation sites at positions Asn-25 and Asn-97 of its 143 amino acid long mature polypeptide chain.	Nitrogen	26-27	interferon gamma	Homo sapiens	6-22
7532637-2	1994	In normal tissue, SP-A was located preferentially in the alveolar macrophage subpopulation lacking specific binding sites for lectins of the N-acetylgalactosamine group (DBA and SBA), although 50% of MPA-binding macrophages contained SP-A.	Nitrogen	141-142	surfactant protein A1	Rattus norvegicus	18-22
7823027-5	1994	N-glycosylation of NET and SERT appears to be essential for transporter assembly and surface expression, but not for antagonist binding affinity.	Nitrogen	0-1	solute carrier family 6 member 2	Homo sapiens	19-22
7823027-5	1994	N-glycosylation of NET and SERT appears to be essential for transporter assembly and surface expression, but not for antagonist binding affinity.	Nitrogen	0-1	solute carrier family 6 member 4	Homo sapiens	27-31
7523405-0	1994	The effect of N-linked glycosylation on activity of the Na(+)- and Cl(-)-dependent serotonin transporter expressed using recombinant baculovirus in insect cells.	Nitrogen	14-15	solute carrier family 6 member 4	Rattus norvegicus	83-104
7933079-10	1994	Two single point mutations led to the appearance of two extra potential N glycosylation sites in the FIS-2 gag-encoded glycoprotein.	Nitrogen	72-73	long intergenic non-protein coding RNA 1554	Homo sapiens	101-104
7933144-0	1994	Insertion of N-linked glycosylation sites in the variable regions of the human immunodeficiency virus type 1 surface glycoprotein through AAT triplet reiteration.	Nitrogen	13-14	serpin family A member 1	Homo sapiens	138-141
24306501-7	1994	Feeding nitrate to excised leaves of nitrogen deficient plants enhanced the degree of light activation of PEP carboxylase in the C4 species maize, but had little or no effect in the C3 species wheat.	Nitrogen	37-45	phosphoenolpyruvate carboxylase 2	Zea mays	106-109
7523405-11	1994	Similarly, mutated serotonin transporters that contained reduced numbers of N-linked glycosylation sites had unchanged Kd for [125I]RT155 binding whether there were 2, 1, or 0 N-linked glycosylation sites present on the serotonin transporter.	Nitrogen	76-77	solute carrier family 6 member 4	Rattus norvegicus	19-40
7932578-4	1994	Structure-activity studies of the C-terminal heterocyclic groups indicate the importance of an sp2 nitrogen atom at a beta-position from the adjoining ketone carbonyl group.	Nitrogen	99-107	Sp2 transcription factor	Homo sapiens	95-98
7980421-7	1994	N-Desulphated/N-acetylated bovine lung heparin retained only a significant capacity to protect bFGF from tryptic cleavage.	Nitrogen	0-1	fibroblast growth factor 2	Bos taurus	95-99
7980421-7	1994	N-Desulphated/N-acetylated bovine lung heparin retained only a significant capacity to protect bFGF from tryptic cleavage.	Nitrogen	14-15	fibroblast growth factor 2	Bos taurus	95-99
7958950-8	1994	The three sites for N-linked glycosylation in the RHL-1 sequence are all conserved in the deduced MHL-1 sequence.	Nitrogen	20-21	Rh blood group, D antigen	Mus musculus	50-55
7925773-1	1994	Murine interleukin-3 (IL-3) has extensive N-linked glycosylation.	Nitrogen	42-43	interleukin 3	Mus musculus	7-26
7534225-3	1994	In the case of the Trp-P-2, the cytosolic activation was even more potent than the microsomal activation, which is classically ascribed to N-hydroxylation and subsequent esterification.	Nitrogen	139-140	polycystin 2, transient receptor potential cation channel	Homo sapiens	19-26
7812191-5	1994	Two systems can be also determined in wild type cells grown in rich medium containing a mixed nitrogen source where decreased GAP1 function is observed.	Nitrogen	94-102	amino acid permease GAP1	Saccharomyces cerevisiae S288C	126-130
7925474-4	1994	FA1 has six well conserved epidermal-growth-factor motifs and contains up to ten O-glycosylation and N-glycosylation sites, six of which are differentially glycosylated.	Nitrogen	101-102	delta like non-canonical Notch ligand 1	Homo sapiens	0-3
7881178-0	1994	Structural studies of the N-linked sugar chains of human rhodopsin.	Nitrogen	26-27	rhodopsin	Homo sapiens	57-66
7521361-10	1994	Finally, the ability of CD59 to enhance CD58-dependent T cell responses was shown to be dependent on N-glycosylation of CD59 at amino acid Asn18.	Nitrogen	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	24-28
7521361-10	1994	Finally, the ability of CD59 to enhance CD58-dependent T cell responses was shown to be dependent on N-glycosylation of CD59 at amino acid Asn18.	Nitrogen	101-102	CD59 molecule (CD59 blood group)	Homo sapiens	120-124
7925428-8	1994	Rabbit AChE had a larger number of aromatic residues lining the active-site gorge than rabbit BChE (14 compared to 8, respectively) and a smaller number of potential N-glycosylation sites (3 compared to 8, respectively).	Nitrogen	166-167	ACE-1	Oryctolagus cuniculus	7-11
7812613-14	1994	The exchange of 95% O2/5% CO2 gas for 95% N2/5% CO2 gas significantly inhibited the EFS-induced decrease in release of ir-ET-1.	Nitrogen	42-44	endothelin 1	Homo sapiens	122-126
7812191-7	1994	These results show that in S. cerevisiae GAP1, S1 and S2 participate in L-leucine entrance in cells grown in a poor nitrogen source, and that S1 and S2 are two ammonia-sensitive permeases that mediate the uptake in cells grown in a rich nitrogen source.	Nitrogen	116-124	amino acid permease GAP1	Saccharomyces cerevisiae S288C	41-45
7812191-7	1994	These results show that in S. cerevisiae GAP1, S1 and S2 participate in L-leucine entrance in cells grown in a poor nitrogen source, and that S1 and S2 are two ammonia-sensitive permeases that mediate the uptake in cells grown in a rich nitrogen source.	Nitrogen	237-245	amino acid permease GAP1	Saccharomyces cerevisiae S288C	41-45
8085853-4	1994	Inhibition of thymidylate synthase activity in tumor tissue after dosing of AO-90 (nitrogen 0.68g/kg on the 1st day and 1.36 g/kg for the remaining 6 days) by TPN along with daily intraperitoneal dosing of 5-FU (10 mg/kg) was also evaluated with the inoculation of 10(6) tumor cells.	Nitrogen	83-91	thymidylate synthetase	Rattus norvegicus	14-34
7521882-3	1994	The red cell water channel-forming integral protein (Aquaporin CHIP) is a homotetramer with only one N-glycosylated subunit, however no CHIP-associated blood group antigens have yet been identified.	Nitrogen	101-102	aquaporin 1 (Colton blood group)	Homo sapiens	53-67
8077355-1	1994	The reversal of glucocorticoid-induced negative nitrogen balance by GH supports a possible therapeutic role for GH treatment in patients receiving these catabolic steroids.	Nitrogen	48-56	growth hormone 1	Homo sapiens	68-70
8077355-1	1994	The reversal of glucocorticoid-induced negative nitrogen balance by GH supports a possible therapeutic role for GH treatment in patients receiving these catabolic steroids.	Nitrogen	48-56	growth hormone 1	Homo sapiens	112-114
7520996-1	1994	Sensitivity of yeast cells to the bifunctional alkylating agent nitrogen mustard (HN2) depends on two independently operating physiological mechanisms of cellular metabolism: dynamics of uptake of HN2 via choline permease, encoded in the gene HNM1/CTR, and repair of HN2-induced DNA damage.	Nitrogen	64-72	calcitonin receptor	Homo sapiens	248-251
7836708-1	1994	We investigated the inhibitory effect of insulin and glucose on hepatic amino- to urea-nitrogen conversion independent of endogenous insulin and glucagon secretion.	Nitrogen	87-95	insulin	Homo sapiens	41-48
7986852-4	1994	Insulin is the only hormone which produces anabolism in all energetic substrates, but the results published about its administration with glucose and amino acids and its effects upon the nitrogen balance are controversial.	Nitrogen	187-195	insulin	Homo sapiens	0-7
7898457-5	1994	Inhibition of N-linked glycosylation of proteins results in the overproduction of BiP/GRP78.	Nitrogen	14-15	heat shock protein 5	Mus musculus	82-85
7898457-5	1994	Inhibition of N-linked glycosylation of proteins results in the overproduction of BiP/GRP78.	Nitrogen	14-15	heat shock protein 5	Mus musculus	86-91
8068684-0	1994	The Na+/H+ exchanger NHE-1 possesses N- and O-linked glycosylation restricted to the first N-terminal extracellular domain.	Nitrogen	4-5	solute carrier family 9 member A1	Homo sapiens	21-26
8068684-1	1994	The ubiquitously-expressed human Na+H+ exchanger (NHE-1) contains three consensus sites (Asn-X-Ser/Thr) for N-linked glycosylation at asparagines 75, 370, and 410.	Nitrogen	33-34	solute carrier family 9 member A1	Homo sapiens	50-55
7914487-9	1994	The N/O-glycosylated IL-6 was clearly as sensitive to cathepsin-G- and gamma-GT-related activities as the unglycosylated IL-6 from Escherichia coli, thus indicating that the sugar chains did not protect the cleavage sites of the two proteases on the IL-6 molecule.	Nitrogen	4-5	interleukin 6	Homo sapiens	21-25
7811531-14	1994	Taken together, these results suggest that N-myristoylation of Nef affects its association with both membranes and cytoskeleton.	Nitrogen	43-44	S100 calcium binding protein B	Homo sapiens	63-66
7827405-1	1994	The Saccharomyces cerevisiae ALG7, ALG1 and ALG2 genes, whose products function early in the dolichol pathway of protein N-glycosylation, are essential for cell viability, and perturbation in their expression causes G1-specific cell cycle arrest.	Nitrogen	121-122	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Saccharomyces cerevisiae S288C	29-33
7949373-1	1994	Metabolic N-dealkylation is a commonly observed biotransformation with tertiary and secondary amine drugs and related N-alkylated amides, but surprisingly little is known about the cytochrome P-450 isozymes involved in these dealkylation reactions.	Nitrogen	10-11	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	181-197
8060992-0	1994	Contribution to global protein stabilization of the N-capping box in human growth hormone.	Nitrogen	52-53	growth hormone 1	Homo sapiens	75-89
8060992-2	1994	At the N-terminus of helix 2 of human growth hormone there are two residues, Ser71 and Glu74, which form two reciprocal hydrogen bonds between the side chains and the backbone nitrogens of either residue (the N-capping box).	Nitrogen	176-185	growth hormone 1	Homo sapiens	38-52
7520013-4	1994	Seven potential N-linked glycosylation sites are conserved between the three species, suggesting that carbohydrate modification may play an important role in Psel function.	Nitrogen	16-17	selectin P	Rattus norvegicus	158-162
7993663-6	1994	In the four patients studied, all had a significant increase in nitrogen retention over baseline with alanine or growth hormone alone, or with the combination of growth hormone and alanine, with a much greater effect of growth hormone.	Nitrogen	64-72	growth hormone 1	Homo sapiens	113-127
7989134-1	1994	The mitogenicity, lethal toxicity and antitumor activity against Meth A fibrosarcoma and the induction of tumor necrosis factor (TNF) of chemically synthesized N-acylated serine-linked nonphosphorylated acylglucosamine-derived lipid A analog (A-601, A-602 and A-603) were determined.	Nitrogen	130-131	tumor necrosis factor	Mus musculus	106-127
8064373-4	1994	Insulin concentrations showed significant positive relationships with nitrogen balance and prealbumin concentrations; cortisol levels showed a significant negative relationship with nitrogen balance and a significant positive relationship with leucine incorporation into protein.	Nitrogen	70-78	insulin	Homo sapiens	0-7
7518437-4	1994	The absolute asymmetry of the sidedness of their N-glycosylation was employed here to develop such a method using the cystic fibrosis transmembrane conductance regulator (CFTR).	Nitrogen	49-50	CF transmembrane conductance regulator	Homo sapiens	118-169
7518437-4	1994	The absolute asymmetry of the sidedness of their N-glycosylation was employed here to develop such a method using the cystic fibrosis transmembrane conductance regulator (CFTR).	Nitrogen	49-50	CF transmembrane conductance regulator	Homo sapiens	171-175
8034569-3	1994	Rat ECE is a highly glycosylated protein consisting of 10 possible N-linked glycosylation sites, a zinc-binding domain, and a single membrane-spanning region.	Nitrogen	67-68	endothelin converting enzyme 1	Rattus norvegicus	4-7
7518522-3	1994	One of the analogs, cyclo-[-(CH2)3-NH-CO-(CH2)4-Arg-Phe-Phe-N-]-CH2-CO-Leu-Met-NH2, is a highly active, selective agonist for the NK-receptor, while the other, cyclo[-(CH2)2-NH-CO-(CH2)2-Gly-Arg-Phe-Phe-N-]-CH2-CO-Leu-Met-NH2, is inactive.	Nitrogen	60-62	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3	Homo sapiens	130-141
8031847-6	1994	The changes in the hepatocyte redox state, induced by CCl4 and/or adenosine, seem to modify collagen and nitrogen metabolism, indicating a linear correlation between the redox state and the collagen synthesis rate, whereas an inverse relationship was observed with collagenase activity.	Nitrogen	105-113	C-C motif chemokine ligand 4	Rattus norvegicus	54-58
7913507-1	1994	We synthesized a new series of benextramine analogs as neuropeptide Y (NPY) functional group mimetics and tested them for N-[propionyl-3H]NPY ([3]NPY) displacement activity in rat brain membrane homogenates and for NPY receptor antagonist activity in the rat femoral artery.	Nitrogen	71-72	neuropeptide Y	Rattus norvegicus	55-69
7982287-9	1994	CER by concomitant infusion of a subpressor dose of angiotensin II (AII) attenuated the progressive reduction of GLU release (87 +/- 4%, P &lt; 0.05 compared with NTG group), whereas GLY release was not affected (106 +/- 5%, NS compared with NTG group).	Nitrogen	225-227	angiotensinogen	Rattus norvegicus	52-66
7518670-2	1994	BAF increased intravesicular pH and enhanced nitrite release by activated macrophages; however, the NO concentration necessary to kill parasites was higher in BAF-exposed than control macrophages, suggesting that microbicidal nitrogen derivatives were less active at alkaline pH.	Nitrogen	226-234	BAF nuclear assembly factor 1	Homo sapiens	0-3
7518670-2	1994	BAF increased intravesicular pH and enhanced nitrite release by activated macrophages; however, the NO concentration necessary to kill parasites was higher in BAF-exposed than control macrophages, suggesting that microbicidal nitrogen derivatives were less active at alkaline pH.	Nitrogen	226-234	BAF nuclear assembly factor 1	Homo sapiens	159-162
7982287-9	1994	CER by concomitant infusion of a subpressor dose of angiotensin II (AII) attenuated the progressive reduction of GLU release (87 +/- 4%, P &lt; 0.05 compared with NTG group), whereas GLY release was not affected (106 +/- 5%, NS compared with NTG group).	Nitrogen	225-227	angiotensinogen	Rattus norvegicus	68-71
8031418-2	1994	The tetrameric lectin from Glycine max (soybean) (SBA) has been shown to cross-link and precipitate with N-linked multiantennary complex type oligosaccharides containing nonreducing terminal Gal residues (Bhattacharyya, L., Haraldsson, M., &amp; Brewer, C. F. (1988) Biochemistry 27, 1034-1041).	Nitrogen	105-106	LOW QUALITY PROTEIN: lectin	Glycine max	15-21
8033999-5	1994	NTR1 seems to be involved in the supply of reproductive organs with nitrogen as it is expressed at low levels in leaves and highly in developing pods.	Nitrogen	68-76	mRNA splicing protein SPP382	Saccharomyces cerevisiae S288C	0-4
7515065-5	1994	Here, we demonstrate that IL-1 beta diminished markedly the pp63 production by affecting its mRNA transcription and that the cytokine was able to modify the N-glycosylation process of the protein.	Nitrogen	95-96	interleukin 1 beta	Rattus norvegicus	26-35
24186048-3	1994	Recent demonstration of glutamine synthetase and DAHP synthase in the vascular tisuue has added a new dimension in the complexity of the nitrogen cycle in plants.	Nitrogen	137-145	glutamate-ammonia ligase	Homo sapiens	24-44
8196060-2	1994	Approximately 10% of interactions between sp2 hybridized nitrogen atoms, from either side-chains or main-chains, and phenylalanine or tyrosine rings have the nitrogen atom positioned above the ring.	Nitrogen	57-65	Sp2 transcription factor	Homo sapiens	42-45
8196060-2	1994	Approximately 10% of interactions between sp2 hybridized nitrogen atoms, from either side-chains or main-chains, and phenylalanine or tyrosine rings have the nitrogen atom positioned above the ring.	Nitrogen	158-166	Sp2 transcription factor	Homo sapiens	42-45
7913322-5	1994	The 2-pyridyl group with a basic nitrogen atom attached at position 3 of indole in an appropriate spatial orientation seems to be an important feature for the interaction of the indole derivatives with P-gp.	Nitrogen	33-41	ATP binding cassette subfamily B member 1	Homo sapiens	202-206
8203982-2	1994	SUMMARY BACKGROUND DATA: The anabolic effect of growth hormone administration is associated with nitrogen retention and an increase muscle strength, but the impact of growth hormone on nutrient uptake from the gut lumen has not been examined.	Nitrogen	97-105	growth hormone 1	Homo sapiens	48-62
7937704-4	1994	The H-D exchange rate of the N-1 proton in the Trp63 which is located in the active site cleft, was enhanced in the Del-Arg14His15 lysozyme, while 2-D proton NMR analysis revealed no conformational change around Trp63.	Nitrogen	29-30	lysozyme	Homo sapiens	131-139
7518124-0	1994	Enhancement of the complement regulatory function of CD59 by site-directed mutagenesis at the N-glycosylation site.	Nitrogen	94-95	CD59 molecule (CD59 blood group)	Homo sapiens	53-57
8194601-2	1994	The hyperfine couplings of the remote nitrogens of histidine ligands are determined for the first time by an X-band ESEEM spectroscopy study of 15N-substituted superoxide dismutase (SOD).	Nitrogen	38-47	superoxide dismutase 1	Homo sapiens	160-180
8194601-2	1994	The hyperfine couplings of the remote nitrogens of histidine ligands are determined for the first time by an X-band ESEEM spectroscopy study of 15N-substituted superoxide dismutase (SOD).	Nitrogen	38-47	superoxide dismutase 1	Homo sapiens	182-185
8180186-2	1994	The tetrameric lectin from Glycine max (soybean) (SBA) has been shown to cross-link and precipitate with N-linked multiantennary complex type oligosaccharides containing nonreducing terminal Gal residues (Bhattacharyya, L., Haraldsson, M., &amp; Brewer, C. F. (1988) Biochemistry 27, 1034-1041).	Nitrogen	105-106	LOW QUALITY PROTEIN: lectin	Glycine max	15-21
8204106-9	1994	Prior incubation of microsomes with 100 microM gestodene, known to be a selective mechanism-based inhibitor of CYP3A4 in the presence of NADPH, led to 76 +/- 6 and 76 +/- 5% (N = 5 samples) reductions in the N-demethylation and formation of TOR III, respectively.	Nitrogen	137-138	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	111-117
8176214-9	1994	It turned out that a potential N-glycosylation site close to the proteolytic cleavage site of the IL-6R is used.	Nitrogen	31-32	interleukin 6 receptor	Homo sapiens	98-103
7512951-1	1994	Endothelial nitric oxide synthase (eNOS) is unique among the nitric oxide synthase family of proteins due to the presence of an N-myristoylation consensus sequence elucidated from the cloning of its cDNA.	Nitrogen	36-37	nitric oxide synthase 3	Bos taurus	0-33
8070328-0	1994	N-hydroxylation of the antiprotozoal drug pentamidine catalyzed by rabbit liver cytochrome P-450 2C3 or human liver microsomes, microsomal retroreduction, and further oxidative transformation of the formed amidoximes.	Nitrogen	0-1	LOW QUALITY PROTEIN: cytochrome P450 2C3	Oryctolagus cuniculus	80-100
7926625-3	1994	In the pituitary of the sturgeon, N-acetylated forms of alpha-MSH represented 91% of the total alpha-MSH isolated.	Nitrogen	34-35	proopiomelanocortin	Homo sapiens	56-65
7926625-3	1994	In the pituitary of the sturgeon, N-acetylated forms of alpha-MSH represented 91% of the total alpha-MSH isolated.	Nitrogen	34-35	proopiomelanocortin	Homo sapiens	95-104
7926625-5	1994	The presence of N-acetylated forms of alpha-MSH in the pituitaries of representatives of the two extant genera of chondrostean fish coupled with the observation that N-acetylated forms of alpha-MSH are present in the pituitaries of cladistian and neopterygian fishes indicates that the alpha-MSH specific N-acetylation mechanism evolved prior to the radiation of the Actinopterygii.	Nitrogen	16-17	proopiomelanocortin	Homo sapiens	38-47
7926625-5	1994	The presence of N-acetylated forms of alpha-MSH in the pituitaries of representatives of the two extant genera of chondrostean fish coupled with the observation that N-acetylated forms of alpha-MSH are present in the pituitaries of cladistian and neopterygian fishes indicates that the alpha-MSH specific N-acetylation mechanism evolved prior to the radiation of the Actinopterygii.	Nitrogen	166-167	proopiomelanocortin	Homo sapiens	188-197
7926625-5	1994	The presence of N-acetylated forms of alpha-MSH in the pituitaries of representatives of the two extant genera of chondrostean fish coupled with the observation that N-acetylated forms of alpha-MSH are present in the pituitaries of cladistian and neopterygian fishes indicates that the alpha-MSH specific N-acetylation mechanism evolved prior to the radiation of the Actinopterygii.	Nitrogen	166-167	proopiomelanocortin	Homo sapiens	188-197
7926625-5	1994	The presence of N-acetylated forms of alpha-MSH in the pituitaries of representatives of the two extant genera of chondrostean fish coupled with the observation that N-acetylated forms of alpha-MSH are present in the pituitaries of cladistian and neopterygian fishes indicates that the alpha-MSH specific N-acetylation mechanism evolved prior to the radiation of the Actinopterygii.	Nitrogen	166-167	proopiomelanocortin	Homo sapiens	188-197
7926625-5	1994	The presence of N-acetylated forms of alpha-MSH in the pituitaries of representatives of the two extant genera of chondrostean fish coupled with the observation that N-acetylated forms of alpha-MSH are present in the pituitaries of cladistian and neopterygian fishes indicates that the alpha-MSH specific N-acetylation mechanism evolved prior to the radiation of the Actinopterygii.	Nitrogen	166-167	proopiomelanocortin	Homo sapiens	188-197
8064995-0	1994	Anabolic effects of insulin and amino acids in promoting nitrogen accretion in postoperative patients.	Nitrogen	57-65	insulin	Homo sapiens	20-27
8064995-1	1994	The present study evaluates the effect of insulin and amino acids on nitrogen balance in the immediate postoperative period in moderately stressed patients who have undergone major abdominal surgical operations.	Nitrogen	69-77	insulin	Homo sapiens	42-49
8190099-1	1994	As recently reported, B-003 (6-S-hexadecyl-2-methoxythioascorbic acid) shows strong inhibition of the N-formylmethionylleucyl phenylalanine (fMLP)-stimulated neutrophil superoxide production and degranulation ex vivo, which is not correlated with its antioxidant properties.	Nitrogen	102-103	formyl peptide receptor 1	Homo sapiens	141-145
7909170-3	1994	[URE3] depends for its propagation on the URE2 product (Ure2p), a negative regulator of enzymes of nitrogen metabolism.	Nitrogen	99-107	glutathione peroxidase	Saccharomyces cerevisiae S288C	42-46
7909170-3	1994	[URE3] depends for its propagation on the URE2 product (Ure2p), a negative regulator of enzymes of nitrogen metabolism.	Nitrogen	99-107	glutathione peroxidase	Saccharomyces cerevisiae S288C	56-61
7511942-2	1994	NO is synthesized from one of the guanidino nitrogens of L-arginine by the enzyme nitric oxide synthase (NOS).	Nitrogen	44-53	nitric oxide synthase 2	Homo sapiens	82-103
18615748-1	1994	The N-linked glycosylation of the recombinant protein mouse placental lactogen-I (mPL-I) expressed by Chinese hamster ovary (CHO) cells under nongrowth conditions was inhibited by increasing levels of ammonium chloride (3 and 9 mM) in a serum-free, protein expression medium.	Nitrogen	4-5	prolactin family 3, subfamily d, member 1	Mus musculus	60-80
7951567-3	1994	In contrast, plasma proinsulin concentrations were slightly but significantly suppressed in NGT (4.1 +/- 0.2 to 3.7 +/- 0.2 pmol/L, P &lt; 0.05), but not in patients with BGI (4.6 +/- 0.3 to 4.8 +/- 0.5 pmol/L, NS) and NIDDM (5.5 +/- 0.5 to 4.9 +/- 0.4 pmol/L, NS).	Nitrogen	211-213	insulin	Homo sapiens	20-30
8138587-3	1994	Sensitivity to tunicamycin indicated that N-linked post-translational modifications to this 43 kDa core species generated the full complement of 50 kDa (intermediate) and 52 kDa (mature) p52(PAI-1) glycosylated isoforms.	Nitrogen	42-43	serpin family E member 1	Rattus norvegicus	191-196
8161344-7	1994	A strong correlation (P &lt; 0.001) was observed between CYP3A4 expression and both activation and N-dechloroethylation of ifosfamide.	Nitrogen	99-100	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	57-63
8132570-8	1994	Based upon these results, we conclude that 1) GPIIIa residue 636 specifically controls the formation and expression of the Sra alloantigenic determinant, and 2) an unpaired cysteine residue alters the N-linked glycosylation pattern of the extracellular domain of GPIIIa, but affects neither the degree of surface expression nor the adhesive function of the GPIIb-IIIa complex.	Nitrogen	201-202	integrin subunit beta 3	Homo sapiens	46-52
8187369-0	1994	The plasma concentration of N-terminal proatrial natriuretic factor ANF(1-98) is related to prognosis in severe heart failure.	Nitrogen	28-29	natriuretic peptide A	Homo sapiens	68-71
8140420-2	1994	An IL-8 analog was chemically synthesized, with the amide nitrogen of leucine-25 methylated to selectivity block formation of hydrogen bonds between monomers and thereby prevent dimerization.	Nitrogen	58-66	C-X-C motif chemokine ligand 8	Homo sapiens	3-7
8132654-15	1994	Specificity of the initial apoB cleavage may require the proper N-linked glycosylation of the protein in the endoplasmic reticulum.	Nitrogen	64-65	apolipoprotein B	Homo sapiens	27-31
18615748-1	1994	The N-linked glycosylation of the recombinant protein mouse placental lactogen-I (mPL-I) expressed by Chinese hamster ovary (CHO) cells under nongrowth conditions was inhibited by increasing levels of ammonium chloride (3 and 9 mM) in a serum-free, protein expression medium.	Nitrogen	4-5	prolactin family 3, subfamily d, member 1	Mus musculus	82-87
8194743-4	1994	Based on a comparison of the reversed-phase HPLC properties and the net positive charges (pH 2.75) of the Lacerta forms of alpha-MSH to those of the mammalian forms of alpha-MSH and Anolis carolinensis ACTH(1-13)NH2, it appears that the N-acetylation of alpha-MSH is a major post-translational processing event in the pars intermedia of L. galloti.	Nitrogen	212-213	proopiomelanocortin	Homo sapiens	123-132
8013286-10	1994	These N-dealkylated metabolites were also present in pooled human plasma samples along with nefazodone, OH-Nef, and an unknown metabolite that was present in plasma in large amounts relative to nefazodone and OH-Nef.	Nitrogen	6-7	S100 calcium binding protein B	Homo sapiens	107-110
8013286-10	1994	These N-dealkylated metabolites were also present in pooled human plasma samples along with nefazodone, OH-Nef, and an unknown metabolite that was present in plasma in large amounts relative to nefazodone and OH-Nef.	Nitrogen	6-7	S100 calcium binding protein B	Homo sapiens	212-215
8126703-7	1994	The observation of parallel structure-binding affinity profiles with respect to sites of N-methylation in the C-terminal regions of tetrapeptide vs heptapeptide CCK analogues suggests that the two series interact similarly with the CCK-A receptor.	Nitrogen	89-90	cholecystokinin	Homo sapiens	161-164
8073631-3	1994	An additional potential N-linked glycosylation site was added by point mutation, which was supported by the observation that the hemagglutinin of the AK-1 strain was stained more heavily after NaDodSO4-PAGE and periodic acid-Schiff (PAS) staining than the Edmonston strain.	Nitrogen	24-25	adenylate kinase 1	Homo sapiens	150-154
7510711-7	1994	After removal of N-linked carbohydrate chains, beta OL and beta 1 comigrated in SDS-PAGE and peptide maps of the two deglycosylated subunits were identical, suggesting differential glycosylation of beta 1 and beta OL accounts entirely for their size differences.	Nitrogen	17-18	integrin subunit beta 1	Rattus norvegicus	47-54
7509843-6	1994	Immunoprecipitation of the LGL-1 antigen reveals a highly disulfide-linked 40-kDa homodimer subunit that is N-glycosylated.	Nitrogen	108-109	LLGL1 scribble cell polarity complex component	Mus musculus	27-32
8193553-1	1994	Alterations in N- and O-linked glycosylation affect cell surface expression and antigenicity of recombinant glycophorin A expressed in transfected Chinese hamster ovary (CHO) cells.	Nitrogen	15-16	glycophorin A (MNS blood group)	Homo sapiens	108-121
8110797-7	1994	Inhibition of N-glycosylation by tunicamycin also increased the binding of monoclonal antibody LRB 200 to hepatocyte apoB.	Nitrogen	14-15	apolipoprotein B	Rattus norvegicus	117-121
8110752-5	1994	The cDNA for FR-gamma predicts a 243-residue polypeptide with an amino acid sequence homology of 71% and 79% with FR-alpha and FR-beta, respectively, a 23-residue amino-terminal signal peptide, and 3 potential sites for N-linked glycosylation.	Nitrogen	6-7	folate receptor gamma	Homo sapiens	13-21
8209340-11	1994	This implies that the extra insulin supplied was caused by physically dissolved nitrogen and oxygen in the insulin solution, and was not due to dysfunction of the pumps.	Nitrogen	80-88	insulin	Homo sapiens	28-35
8209340-11	1994	This implies that the extra insulin supplied was caused by physically dissolved nitrogen and oxygen in the insulin solution, and was not due to dysfunction of the pumps.	Nitrogen	80-88	insulin	Homo sapiens	107-114
8106386-4	1994	In contrast, when the NH2-terminal domain of FPR was replaced by the corresponding region from C5aR or FPRH normal expression to the plasma membrane and high affinity binding of N-formylated peptides were observed.	Nitrogen	22-23	formyl peptide receptor 1	Homo sapiens	45-48
7765932-1	1994	The relationship between synthesis and N-linked glycosylation site occupancy of recombinant human prolactin produced from C127 cells was studied with the aid of a battery of protein synthesis inhibitors.	Nitrogen	39-40	prolactin	Homo sapiens	98-107
8173309-0	1994	Improved cumulated nitrogen balance after administration of recombinant human growth hormone in patients undergoing gastrointestinal surgery.	Nitrogen	19-27	growth hormone 1	Homo sapiens	78-92
7508949-11	1994	Treatment with low dose recombinant IGF-I produces significant, but transient, nitrogen retention.	Nitrogen	79-87	insulin like growth factor 1	Homo sapiens	36-41
8114674-4	1994	Enzymatically active recombinant hPGHS-1 and hPGHS-2 were present as glycosylated proteins in the microsomal fraction prepared from infected cells, whereas recombinant hPGHS-1 and hPGHS-2 prepared from the microsomal fraction of cells treated with tunicamycin, an inhibitor of N-linked glycosylation, were enzymatically inactive.	Nitrogen	277-278	prostaglandin-endoperoxide synthase 1	Homo sapiens	33-40
8202632-1	1994	N-Acetylation, which is catalyzed by the enzymes N-acetyltransferase (NAT), is an important biotransformation pathway for the elimination of a wide variety of xenobiotics.	Nitrogen	0-1	N-acetyltransferase 1	Rattus norvegicus	49-68
8202632-1	1994	N-Acetylation, which is catalyzed by the enzymes N-acetyltransferase (NAT), is an important biotransformation pathway for the elimination of a wide variety of xenobiotics.	Nitrogen	0-1	N-acetyltransferase 1	Rattus norvegicus	70-73
8011427-3	1994	We show here that (1) in CHO-Y2 cells, basal endocytosis, like insulin-induced internalization, was markedly altered despite normal receptor turnover and (2) in both CHO-R and CHO-Y2 cells, basal receptor endocytosis was altered by tunicamycin, an inhibitor of protein N-glycosylation, whereas insulin-induced internalization was not.	Nitrogen	269-270	insulin	Cricetulus griseus	63-70
8206884-7	1994	A portion of recombinant hIL-6 protein carries one N-linked sialooligosaccharide chain, and the N-glycosylation occurs at Asn46.	Nitrogen	51-52	interleukin 6	Homo sapiens	25-30
8304968-7	1994	These results indicated that the N-demethylation of TMO is catalysed mainly by CYP2C11 and 2B1 in rat hepatic microsomes, and that human CYP3A4 and an unspecified isoform of the 2C subfamilies contribute to TMO N-demethylation in human liver.	Nitrogen	211-212	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	137-143
7507111-0	1994	O-glycosylation mimics N-glycosylation in the 16-kDa fragment of bovine pro-opiomelanocortin.	Nitrogen	23-24	proopiomelanocortin	Bos taurus	72-92
8292036-4	1994	Human GnT-V has 741 amino acids and six putative N-glycosylation sites.	Nitrogen	49-50	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	6-11
8082573-7	1994	Considering the selective prerequisites for oxidative attack by cytochrome P-450 at vulnerable nitrogen centers, many cytotoxic amines belonging to the category of relatively rigid, planar molecules undergo N-oxidative activation by the cytochrome P-450IA subfamily, while more bulky amines with flexible conformation are N-oxygenated preferentially by phenobarbital-inducible cytochromes P-450.	Nitrogen	95-103	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	64-80
8082573-7	1994	Considering the selective prerequisites for oxidative attack by cytochrome P-450 at vulnerable nitrogen centers, many cytotoxic amines belonging to the category of relatively rigid, planar molecules undergo N-oxidative activation by the cytochrome P-450IA subfamily, while more bulky amines with flexible conformation are N-oxygenated preferentially by phenobarbital-inducible cytochromes P-450.	Nitrogen	207-208	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	64-80
7925547-2	1994	At present, it appears that daily GH or IGF-I treatment modestly increases nitrogen retention in most normal adults, probably by separate but permissive mechanisms, but only for a short period of time (approximately 1 month).	Nitrogen	75-83	insulin like growth factor 1	Homo sapiens	40-45
8194903-7	1994	The GA733-1 genomic DNA sequence predicted a type-1 membrane protein of 35 kDa, with 4 potential N-linked glycosylation sites.	Nitrogen	21-22	tumor associated calcium signal transducer 2	Homo sapiens	4-11
8262633-4	1994	The CRP purified from parasites treated with an inhibitor of N-linked glycosylation exhibited a decreased binding affinity for C3b compared with that of the fully glycosylated protein.	Nitrogen	61-62	C-reactive protein	Homo sapiens	4-7
7532995-9	1994	Furthermore, surfaces which had incorporated nitrogen were more effective than were oxygen-containing films in adsorbing sufficient serum Fn as to promote endothelial cell attachment.	Nitrogen	45-53	fibronectin 1	Homo sapiens	138-140
8172984-6	1994	The nitrogen balance revealed a univariant and significant linear correlation with IGF-1 (r = 0.373, p &lt; 0.05) and with prealbumin (r = 0.377, p &lt; 0.05).	Nitrogen	4-12	insulin like growth factor 1	Homo sapiens	83-88
8275975-2	1994	In the present study, we investigated whether the N-acetylated beta-endorphin- and alpha-MSH-related peptides that are characteristically produced by melanotropes in the rat and other species are localized in the human pituitary.	Nitrogen	50-51	proopiomelanocortin	Homo sapiens	63-77
8019599-1	1994	The human erythrocyte anion transporter (band 3; AE1) has a single N-linked glycosylation site at amino residue Asn-642.	Nitrogen	67-68	solute carrier family 4 member 1 (Diego blood group) L homeolog	Xenopus laevis	41-47
8209423-4	1994	Two adjacent ORFs, ORF-1a and ORF-1, were found by computer analysis to have the properties of two introns encoding a glycoprotein: ORF-1a encodes an aa sequence with the properties of a signal peptide, and ORF-1 encodes a polypeptide with a membrane anchor domain and putative N-glycosylation sites in the aa sequence.	Nitrogen	278-279	ORF1	Homo sapiens	19-24
8209423-4	1994	Two adjacent ORFs, ORF-1a and ORF-1, were found by computer analysis to have the properties of two introns encoding a glycoprotein: ORF-1a encodes an aa sequence with the properties of a signal peptide, and ORF-1 encodes a polypeptide with a membrane anchor domain and putative N-glycosylation sites in the aa sequence.	Nitrogen	278-279	ORF1	Homo sapiens	30-35
8299948-0	1993	The 3" flanking region of the human erythropoietin-encoding gene contains nitrogen-regulatory/oxygen-sensing consensus sequences and tissue-specific transcriptional regulatory elements.	Nitrogen	74-82	erythropoietin	Homo sapiens	36-50
7904155-4	1993	N-deglycosylation of HEK cell membranes yielded a 165,000-M(r) immunoreactive species, which is in agreement with the size predicted from the cDNA sequence for the mature NMDAR2A subunit.	Nitrogen	0-1	glutamate ionotropic receptor NMDA type subunit 2A	Homo sapiens	171-178
8258372-0	1993	Effects of growth hormone on nitrogen balance in the hypermetabolic state: a selected review of the literature.	Nitrogen	29-37	growth hormone 1	Homo sapiens	11-25
8267652-4	1993	In the liver perfused with fructose-supplemented regular KHB equilibrated with 95% N2-5% CO2, infusion of 0.5 mM CCl4 caused an early uptake of Ca2+ coupled with K+ leakage and Na+ uptake within the infusion time of 30 min, which was followed by a marked lactic dehydrogenase (LDH) leakage into the effluent perfusate and further Ca2+ uptake by the liver.	Nitrogen	83-85	C-C motif chemokine ligand 4	Rattus norvegicus	113-117
8226900-5	1993	The 50-DAG deduced amino acid sequence predicts a novel protein having 387 amino acids, a 17-amino acid signal sequence, one transmembrane domain, and two potential sites of N-linked glycosylation.	Nitrogen	174-175	alpha-sarcoglycan	Oryctolagus cuniculus	4-10
8148870-0	1993	Cytochrome P450 mediated metabolism of diazepam in human and rat: involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner.	Nitrogen	96-97	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-15
8218262-0	1993	Inhibition of protein kinase C by N-myristoylated peptide substrate analogs.	Nitrogen	34-35	proline rich transmembrane protein 2	Homo sapiens	14-30
8218262-7	1993	Our results support a mechanism in which the N-myristoylated peptides inhibit the catalytic fragment by binding to PKCfree, but not to the complex PKC-ATP, at the protein-substrate binding site.	Nitrogen	45-46	proline rich transmembrane protein 2	Homo sapiens	115-118
8246228-5	1993	These results are consistent with a stabilizing stereoelectronic effect on the enzyme adduct caused by N-methylation which hinders free rotation and prevents the sp3-orbital containing the nitrogen nonbonded electrons from being trans to the active site amino acid leaving group.	Nitrogen	103-104	Sp3 transcription factor	Homo sapiens	162-165
8246228-5	1993	These results are consistent with a stabilizing stereoelectronic effect on the enzyme adduct caused by N-methylation which hinders free rotation and prevents the sp3-orbital containing the nitrogen nonbonded electrons from being trans to the active site amino acid leaving group.	Nitrogen	189-197	Sp3 transcription factor	Homo sapiens	162-165
8218262-4	1993	Recently, we reported that N-myristoylation of the synthetic peptide substrate Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu (RKRTLRRL) transformed a peptide that completely lacked inhibitory activity against the histone kinase reactions of PKC and its catalytic fragment into a peptide that potently inhibited both of these reactions.	Nitrogen	27-28	proline rich transmembrane protein 2	Homo sapiens	227-230
16349084-12	1993	Ectocellular aminopeptidase may be common in marine synechococci and play roles in their nitrogen nutrition, particularly in low-nitrate and low-light environments.	Nitrogen	89-97	carboxypeptidase Q	Homo sapiens	13-27
8298500-0	1993	N-linked glycosylation of the C5a receptor.	Nitrogen	0-1	complement C5a receptor 1	Homo sapiens	30-42
8240300-7	1993	Furthermore, the association of the various glycosylation-deficient forms of the CD-MPR with BiP correlated inversely with their ability to bind Man-6-P. From these results we conclude that N-glycosylation of the bovine CD-MPR facilities the folding of the nascent polypeptide chain into a conformation that is conductive for intracellular transport and ligand binding.	Nitrogen	190-191	heat shock protein family A (Hsp70) member 5	Homo sapiens	93-96
7764337-8	1993	Complete removal of N-linked sugars converted the native Epo to the deglycosylated form with 18 kDa.	Nitrogen	20-21	erythropoietin	Homo sapiens	57-60
8298500-1	1993	The recent cloning of the cDNA encoding the human C5a receptor reveals a single potential site for N-linked glycosylation.	Nitrogen	28-29	complement C5a receptor 1	Homo sapiens	50-62
8282089-9	1993	N-glycosylation of human C5a receptor was found to be dispensable for the function of the receptor.	Nitrogen	0-1	complement C5a receptor 1	Homo sapiens	25-37
7905403-0	1993	Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions.	Nitrogen	28-29	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	13-18
8254337-1	1993	The pentapeptide fragment of ANF, Asn-Ser-Phe-Arg-Tyr-NH2, coordinates to Cu(II) using the same four nitrogen donor centers as simple pentapeptides such as pentaalanine yet the complexes are of much higher stability as a result of a highly organized side-chain structure which is present in the complex but absent from the free ligand.	Nitrogen	101-109	natriuretic peptide A	Homo sapiens	29-32
7691950-10	1993	Furthermore, the synthetic lipid PPDm2 (a 1,4-bisphosphorylated and N,N-diacylated derivative of 2,3-diamino-2,3-dideoxy-D-glucose) inhibited LPS-induced, but not TNF-induced, expression of LpsR.	Nitrogen	68-69	toll-like receptor 4	Mus musculus	142-145
8407908-9	1993	Mature GPV was composed of 544 amino acids which contained a single transmembrane domain, a short cytoplasmic domain (16 residues), and a large extracellular domain with 8 potential N-glycosylation sites.	Nitrogen	182-183	glycoprotein V platelet	Homo sapiens	7-10
8409422-4	1993	The IPO-3 Ag is a single-chain heavily N-glycosylated phosphoglycoprotein approximately 75 to 95 kDa in size with a 42-kDa protein core.	Nitrogen	39-40	signaling lymphocytic activation molecule family member 1	Homo sapiens	4-9
8240320-0	1993	N-glycosylation of forms of angiotensin converting enzyme from four mammalian species.	Nitrogen	0-1	angiotensin I converting enzyme	Homo sapiens	28-57
8240320-1	1993	To help clarify bases for the molecular weight and surface charge heterogeneities of forms of somatic angiotensin converting enzyme (ACE), we examined for differences in N-glycosylation.	Nitrogen	170-171	angiotensin I converting enzyme	Homo sapiens	133-136
8240320-2	1993	ACE preparations purified from human, guinea pig, rat and rabbit tissues were found to be heterogeneous in terms of numbers of N-glycosylated sites (7-8 sites per molecule of ACE) and in types of structures of oligosaccharides used for glycosylation (complex versus high mannose oligosaccharide contents).	Nitrogen	127-128	angiotensin I converting enzyme	Homo sapiens	0-3
8240320-3	1993	Our findings, taken with reports of potential N-glycosylation sites and amino acid sequencing data, indicate that ACE forms can differ in terms of degrees of glycosylation, sites of glycosylation and structures of attached oligosaccharide units.	Nitrogen	46-47	angiotensin I converting enzyme	Homo sapiens	114-117
8236277-4	1993	MPO- or MPO-generated oxidants are capable of oxidizing a wide variety of compounds and a broad range of functional groups, especially those that contain nitrogen and sulfur.	Nitrogen	154-162	myeloperoxidase	Homo sapiens	0-4
8236277-4	1993	MPO- or MPO-generated oxidants are capable of oxidizing a wide variety of compounds and a broad range of functional groups, especially those that contain nitrogen and sulfur.	Nitrogen	154-162	myeloperoxidase	Homo sapiens	0-3
12231954-1	1993	Gene expression and protein accumulation patterns of nitrogen-responsive lipoxygenase (LOX-NR), as a representative vegetative storage protein, were investigated in nonnodulated soybeans (Glycine max [L.] Merr.	Nitrogen	53-61	seed linoleate 9S-lipoxygenase-3	Glycine max	87-90
8215639-12	1993	CONCLUSIONS: Temporary insulin suppression during physiologic increases in stress hormone concentrations amplified whole-body nitrogen loss and led to the development of accelerated net skeletal muscle protein breakdown.	Nitrogen	126-134	insulin	Homo sapiens	23-30
8286855-2	1993	We have revised the sites of O-glycosylation in the extracellular domain of GpA by automated solid-phase Edman degradation, which allowed positive identification and quantitation of O-glycosylated Ser and Thr residues, as well as the single N-glycosylation site.	Nitrogen	241-242	glycophorin A (MNS blood group)	Homo sapiens	76-79
8106009-10	1993	The data indicate win4 and BSP genes are differentially regulated, and their products may play important roles in the storage and reallocation of nitrogen in perennial plants.	Nitrogen	146-154	integrin binding sialoprotein	Homo sapiens	27-30
12231954-3	1993	The form of available nitrogen (supplied as NH4NO3, NH4+, NO3-, or urea) influenced the mRNA level and the amount of LOX protein, indicating that preferential accumulation of LOX may occur.	Nitrogen	22-30	seed linoleate 9S-lipoxygenase-3	Glycine max	117-120
12231954-3	1993	The form of available nitrogen (supplied as NH4NO3, NH4+, NO3-, or urea) influenced the mRNA level and the amount of LOX protein, indicating that preferential accumulation of LOX may occur.	Nitrogen	22-30	seed linoleate 9S-lipoxygenase-3	Glycine max	175-178
12231954-4	1993	Soybeans were grown with 0, 2, 5, and 16 mM total nitrogen to determine the extent to which LOX accumulation responded to soil nitrogen levels.	Nitrogen	127-135	seed linoleate 9S-lipoxygenase-3	Glycine max	92-95
12231954-6	1993	A general correlation between increasing available nitrogen level and LOX level was seen in the shoot tip and other organs throughout the soybean life cycle.	Nitrogen	51-59	seed linoleate 9S-lipoxygenase-3	Glycine max	70-73
12231954-7	1993	However, appreciable amounts of LOX-NR mRNA and protein accumulated even when plants were grown under conditions of nitrogen deficiency.	Nitrogen	116-124	seed linoleate 9S-lipoxygenase-3	Glycine max	32-35
12231954-9	1993	The expression patterns of LOX-NR in plants grown under nitrogen deficiency suggest that these proteins, although responsive to nitrogen status, may not function solely as temporary storage pools for amino acids.	Nitrogen	56-64	seed linoleate 9S-lipoxygenase-3	Glycine max	27-30
12231954-9	1993	The expression patterns of LOX-NR in plants grown under nitrogen deficiency suggest that these proteins, although responsive to nitrogen status, may not function solely as temporary storage pools for amino acids.	Nitrogen	128-136	seed linoleate 9S-lipoxygenase-3	Glycine max	27-30
7690715-6	1993	Human P-glycoprotein expressed in S. pombe seemed to lack N-glycosylation.	Nitrogen	58-59	ATP binding cassette subfamily B member 1	Homo sapiens	6-20
8104165-3	1993	The removal of 1, 2 or all 3 of the N-glycosylation sites present in the first extracellular loop of MDR1 P-glycoprotein did not significantly affect the binding of these MAbs.	Nitrogen	36-37	ATP binding cassette subfamily B member 1	Homo sapiens	101-105
8256512-2	1993	The product encoded by the KTR2 gene is a predicted type II membrane protein of 425 amino acid residues with a short cytoplasmic N-terminus, a membrane-spanning region and a large lumenal domain containing residues with a short cytoplasmic N-terminus, a membrane-spanning region and a large lumenal domain containing four potential N-glycosylation sites.	Nitrogen	129-130	mannosyltransferase KTR2	Saccharomyces cerevisiae S288C	27-31
8399138-5	1993	On the basis of a previous normal-mode analysis of the cyanoferric adduct of myeloperoxidase, a bent Fe-C-N linkage is suggested for the cyanide adduct of lactoperoxidase.	Nitrogen	106-107	myeloperoxidase	Homo sapiens	77-92
8399138-5	1993	On the basis of a previous normal-mode analysis of the cyanoferric adduct of myeloperoxidase, a bent Fe-C-N linkage is suggested for the cyanide adduct of lactoperoxidase.	Nitrogen	106-107	lactoperoxidase	Homo sapiens	155-170
8403225-0	1993	Differential inhibition of the DNA binding of transcription factors NF kappa B and OTF-1 by nitrogen mustard and quinacrine mustard: transcriptional implications.	Nitrogen	92-100	nuclear factor kappa B subunit 1	Homo sapiens	68-78
8400241-13	1993	This extends previous results (Remaley et al, J Biol Chem 266:24176, 1991) showing that, in the absence of O-linked glycosylation, some types of N-linked glycosylation can support cell surface expression of glycophorin A.	Nitrogen	145-146	glycophorin A (MNS blood group)	Homo sapiens	207-220
8403225-1	1993	Nitrogen mustard (HN2) and quinacrine mustard (QM) both inhibited the binding of NF kappa B to the GC-rich consensus sequence in the HIV long terminal repeat (LTR), as assessed by gel-shift assays.	Nitrogen	0-8	nuclear factor kappa B subunit 1	Homo sapiens	81-91
8031217-4	1993	AST, ALT, LDH and PNP in the perfusate at the end of normothermic reperfusion were significantly higher in nitrogen and simple storage groups and those of oxygen group were similar to the control.	Nitrogen	107-115	solute carrier family 17 member 5	Homo sapiens	0-3
8413186-0	1993	A tobacco cDNA clone encoding a GATA-1 zinc finger protein homologous to regulators of nitrogen metabolism in fungi.	Nitrogen	87-95	GATA transcription factor 11-like	Nicotiana tabacum	32-58
7901735-2	1993	Spontaneous and induced cellular variants resistant to N-phosphonacetyl-L-aspartate (PALA), which selects for carbamyl-P-synthetase, aspartate transcarbamylase and dihydroorotase (CAD) gene amplification events, and to intermediate concentrations of 2,6-diaminopurine (DAP), which selects for adenine phosphoribosyl transferase (aprt) gene deletion events, were isolated.	Nitrogen	55-56	adenine phosphoribosyltransferase	Cricetulus griseus	293-327
7901735-2	1993	Spontaneous and induced cellular variants resistant to N-phosphonacetyl-L-aspartate (PALA), which selects for carbamyl-P-synthetase, aspartate transcarbamylase and dihydroorotase (CAD) gene amplification events, and to intermediate concentrations of 2,6-diaminopurine (DAP), which selects for adenine phosphoribosyl transferase (aprt) gene deletion events, were isolated.	Nitrogen	55-56	adenine phosphoribosyltransferase	Cricetulus griseus	329-333
8357839-4	1993	Important features of the ZP3 alpha polypeptide include a predicted N-terminal signal sequence, twenty-two cysteine residues, an O-glycosylated domain and potential attachment sites for five N-linked sugar chains.	Nitrogen	68-69	zona pellucida glycoprotein 4	Sus scrofa	26-35
8415812-9	1993	These findings demonstrate that n-3 supplementation modifies the pyrogenic and thermogenic responses to IL-1 beta, probably via changes in eicosanoid metabolism.	Nitrogen	8-9	interleukin 1 beta	Rattus norvegicus	104-113
8335627-7	1993	DUR3 expression is highly sensitive to nitrogen catabolite repression and also has a partial requirement for the GLN3 product.	Nitrogen	39-47	Dur3p	Saccharomyces cerevisiae S288C	0-4
8336735-2	1993	Here we report results concerning one of these mutants, rvs167, which shows reduced viability and abnormal cell morphology upon carbon and nitrogen starvation.	Nitrogen	139-147	amphiphysin	Saccharomyces cerevisiae S288C	56-62
8220439-4	1993	In microsomes, the N-demethylation was inhibited by antibodies raised against CYP3A subfamily members although fetal microsomes were much less sensitive to immunoinhibition than adult microsomes.	Nitrogen	19-20	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	78-83
8220439-10	1993	These data clearly suggest that the N-demethylation of dextromethorphan is dependent on CYP3A and that both CYP2D6 and CYP3A are involved in the overall metabolism of dextromethorphan.	Nitrogen	36-37	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	88-93
8228387-1	1993	Human interferon-gamma (IFN-gamma) has two N-linked glycosylation sites at positions 25 and 97 of the 143-amino-acid-long secretory form.	Nitrogen	26-27	interferon gamma	Homo sapiens	6-22
7902884-5	1993	Blood urea nitrogen and serum creatinine were significantly elevated in rats with anti-Thy 1 nephritis at weeks 4 and 6 compared to normal rats.	Nitrogen	11-19	Thy-1 cell surface antigen	Rattus norvegicus	87-92
8337817-5	1993	Using myxoma virus and recombinant vaccinia virus constructs for experiments with tunicamycin and peptide N-glycosidase F, it is shown that the secreted SERP1 protein is modified by N-linked glycosylation.	Nitrogen	106-107	stress associated endoplasmic reticulum protein 1	Homo sapiens	153-158
8104124-2	1993	Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.	Nitrogen	27-28	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	0-16
8355595-4	1993	Conversely, activities of catalase (CAT, EC 1.11.1.6) and selenium-glutathione peroxidase (SeGSHPx, EC 1.11.1.9) were higher in the N-6 than in 5% N-6 group.	Nitrogen	132-133	catalase	Mus musculus	26-34
8260593-1	1993	Murine interleukin-3 is secreted by activated T cells in three major molecular mass classes, which differ from one another in the extent of their N-linked glycosylation.	Nitrogen	146-147	interleukin 3	Mus musculus	7-20
8513978-1	1993	Two N-linked sites of glycosylation in the insulin receptor were examined for their contribution to insulin binding, tyrosine kinase activity, and receptor biosynthesis.	Nitrogen	4-5	insulin	Homo sapiens	43-50
8325936-0	1993	A 12-kilodalton N-glycosylated growth hormone-related peptide is present in human pituitary extracts.	Nitrogen	16-17	growth hormone 1	Homo sapiens	31-45
7686482-4	1993	The only IGFBPs identified by ligand blotting in media conditioned by BPE-1 cells were N-glycosylated 28 kilodalton and non-N-glycosylated 24 kilodalton IGFBP-4 species.	Nitrogen	87-88	insulin like growth factor binding protein 1	Bos taurus	9-15
8355595-4	1993	Conversely, activities of catalase (CAT, EC 1.11.1.6) and selenium-glutathione peroxidase (SeGSHPx, EC 1.11.1.9) were higher in the N-6 than in 5% N-6 group.	Nitrogen	132-133	catalase	Mus musculus	36-39
8355595-4	1993	Conversely, activities of catalase (CAT, EC 1.11.1.6) and selenium-glutathione peroxidase (SeGSHPx, EC 1.11.1.9) were higher in the N-6 than in 5% N-6 group.	Nitrogen	147-148	catalase	Mus musculus	26-34
8355595-4	1993	Conversely, activities of catalase (CAT, EC 1.11.1.6) and selenium-glutathione peroxidase (SeGSHPx, EC 1.11.1.9) were higher in the N-6 than in 5% N-6 group.	Nitrogen	147-148	catalase	Mus musculus	36-39
8405361-0	1993	The role of N-glycosylation in the targeting and stability of GLUT1 glucose transporter.	Nitrogen	12-13	solute carrier family 2, facilitated glucose transporter member 1	Cricetulus griseus	62-67
8510918-6	1993	The use of N- and C-terminal truncations of this segment demonstrated that as few as 96 amino acids were required for active repression by GAL4-WT1 hybrid proteins in NIH3T3 fibroblasts.	Nitrogen	11-12	WT1 transcription factor	Homo sapiens	144-147
8400589-8	1993	The persistent low levels of IGF-1 reflect the altered nutrition status of the patients, as characterized by the continued negative nitrogen balance and elevated cortisol levels in the early posttrauma period.	Nitrogen	132-140	insulin like growth factor 1	Homo sapiens	29-34
8509401-10	1993	AG1 contains single RGD integrin binding and N-glycosylation sequences.	Nitrogen	45-46	NBPF member 10	Homo sapiens	0-3
8315675-9	1993	A negative nitrogen balance was associated with the urinary excretion of epinephrine and norepinephrine, with caloric balance, and with plasma C-reactive protein during days 1 and 2 after injury.	Nitrogen	11-19	C-reactive protein	Homo sapiens	143-161
8509335-5	1993	Northern (RNA) analysis reveals a unique SSG1-specific transcript, 1.7 kb long, which can be detected only in sporulating diploids (MATa/MAT alpha) but does not appear in vegetatively growing cells or in nonsporulating diploids (MAT alpha/MAT alpha) when incubated under nitrogen starvation conditions.	Nitrogen	271-279	glucan 1,3-beta-glucosidase	Saccharomyces cerevisiae S288C	41-45
8098269-8	1993	The variation of P-glycoprotein size in the RCC was attributed to differential N-linked glycosylation.	Nitrogen	79-80	ATP binding cassette subfamily B member 1	Homo sapiens	17-31
8494888-3	1993	The purpose of this study was to see if variable N-linked glycosylation could explain the microheterogeneity of CETP.	Nitrogen	49-50	cholesteryl ester transfer protein	Homo sapiens	112-116
8494888-7	1993	To explore this hypothesis further, each of the four potential N-linked glycosylation sites of CETP (at amino acid positions 88, 240, 341, and 396) was eliminated by mutagenesis of asparagine to glutamine.	Nitrogen	63-64	cholesteryl ester transfer protein	Homo sapiens	95-99
7916633-6	1993	Sequence analysis revealed that the isolated trehalase cDNA contains 3103 nucleotides and comprises 579 amino acids, including a cleavable signal sequence and five potential N-glycosylation sites.	Nitrogen	57-58	trehalase	Bombyx mori	45-54
8507209-0	1993	In vitro translation of the human insulin proreceptor results in N-linked glycosylation without dimer formation.	Nitrogen	65-66	insulin	Homo sapiens	34-41
8500166-3	1993	In preadipocytes, multiple discrete forms of pref-1 protein of 45-60 kd are present, owing in part to N-linked glycosylation.	Nitrogen	102-103	delta like non-canonical Notch ligand 1	Homo sapiens	45-51
8501464-7	1993	Apparent distances between the heme iron of lactoperoxidase and either the carbon or nitrogen atoms of bound thiocyanate ion have been determined through application of the Solomon-Bloembergen equation.	Nitrogen	85-93	lactoperoxidase	Homo sapiens	44-59
8463339-0	1993	G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.	Nitrogen	20-28	cyclin A2	Homo sapiens	60-68
8329195-4	1993	In addition, among the nude mice with xid expression, the takes were slightly better in nude mice with a CBA/N background than in those with a NIH(S) background.	Nitrogen	109-110	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	38-41
8494607-7	1993	In the absence of the pro sequence, N-glycoylation at Asn-75 was essential for the secretion of active renin protein from all three cell types.	Nitrogen	36-37	renin	Homo sapiens	103-108
8387532-1	1993	The K-FGF/HST (FGF-4) growth factor is a member of the FGF family which is efficiently secreted and contains a single N-linked glycosylation signal.	Nitrogen	118-119	fibroblast growth factor 4	Homo sapiens	4-9
8387532-1	1993	The K-FGF/HST (FGF-4) growth factor is a member of the FGF family which is efficiently secreted and contains a single N-linked glycosylation signal.	Nitrogen	118-119	fibroblast growth factor 4	Homo sapiens	10-13
8387532-1	1993	The K-FGF/HST (FGF-4) growth factor is a member of the FGF family which is efficiently secreted and contains a single N-linked glycosylation signal.	Nitrogen	118-119	fibroblast growth factor 4	Homo sapiens	15-20
8387532-1	1993	The K-FGF/HST (FGF-4) growth factor is a member of the FGF family which is efficiently secreted and contains a single N-linked glycosylation signal.	Nitrogen	118-119	fibroblast growth factor 4	Homo sapiens	6-9
8510658-6	1993	nia1, nia2 double mutants have only 0.5% of wild-type shoot NR activity and display very poor growth on media with nitrate as the only form of nitrogen.	Nitrogen	143-151	nitrate reductase 1	Arabidopsis thaliana	0-4
8387917-1	1993	Transcription of the Saccharomyces cerevisiae CTT1 gene encoding the cytosolic catalase T is activated by a variety of stress conditions: it is derepressed by nitrogen starvation and induced by heat shock.	Nitrogen	159-167	catalase T	Saccharomyces cerevisiae S288C	46-50
8387917-3	1993	This study shows that a CTT1 upstream region previously found to be involved in nitrogen, cAMP and heat control (base pairs -382 to -325) contains a UAS element (STRE, -368 to -356), which is sufficient for the activation of a reporter gene by all types of stress acting on CTT1.	Nitrogen	80-88	catalase T	Saccharomyces cerevisiae S288C	24-28
8387917-3	1993	This study shows that a CTT1 upstream region previously found to be involved in nitrogen, cAMP and heat control (base pairs -382 to -325) contains a UAS element (STRE, -368 to -356), which is sufficient for the activation of a reporter gene by all types of stress acting on CTT1.	Nitrogen	80-88	catalase T	Saccharomyces cerevisiae S288C	274-278
8096511-0	1993	N-glycosylation and deletion mutants of the human MDR1 P-glycoprotein.	Nitrogen	0-1	ATP binding cassette subfamily B member 1	Homo sapiens	55-69
8483933-2	1993	The resultant N-glycosylated molecular model is consistent with known properties of gp120 and docks with CD4 with a substantial reduction in the sum of the internal potential energies of the individual proteins (delta E = -200 kcal/mol).	Nitrogen	14-15	CD4 molecule	Homo sapiens	105-108
8466313-2	1993	SUMMARY BACKGROUND DATA: Growth hormone attenuates net nitrogen loss after surgical trauma.	Nitrogen	55-63	growth hormone 1	Homo sapiens	25-39
8466313-7	1993	RESULTS: The second postoperative day, growth hormone abolished forearm efflux of total amino acid nitrogen (GH: 170 +/- 117, PL: -785 +/- 192 nmol/100 mL/min, p = .0007) due to reduced losses of both essential and nonessential amino acids.	Nitrogen	99-107	growth hormone 1	Homo sapiens	39-53
8466313-7	1993	RESULTS: The second postoperative day, growth hormone abolished forearm efflux of total amino acid nitrogen (GH: 170 +/- 117, PL: -785 +/- 192 nmol/100 mL/min, p = .0007) due to reduced losses of both essential and nonessential amino acids.	Nitrogen	99-107	growth hormone 1	Homo sapiens	109-111
8466313-11	1993	CONCLUSIONS: When given after gastrointestinal surgery in patients treated with total parenteral nutrition, growth hormone treatment abolished glutamine, 3-methylhistidine, and total amino acid nitrogen loss from forearm tissue.	Nitrogen	194-202	growth hormone 1	Homo sapiens	108-122
8097179-9	1993	The presence of multiple GroEL homologues in R. meliloti suggests a possible role of the GroEL or HSP60 chaperonins in the nodulation (symbiosis) and nitrogen fixation processes.	Nitrogen	150-158	groEL	Sinorhizobium meliloti	25-30
8097179-9	1993	The presence of multiple GroEL homologues in R. meliloti suggests a possible role of the GroEL or HSP60 chaperonins in the nodulation (symbiosis) and nitrogen fixation processes.	Nitrogen	150-158	groEL	Sinorhizobium meliloti	89-94
7680289-3	1993	To test the hypothesis that N-myristoylation is necessary for particulate ECNOS, we performed site-directed mutagenesis of the myristic acid acceptor site, Gly-2, and changed the glycine codon to alanine by a single nucleotide substitution.	Nitrogen	28-29	nitric oxide synthase 3	Bos taurus	74-79
8096511-2	1993	To investigate the significance of the conserved N-glycosylation sites present in the putative first extracellular loop of P-glycoproteins, we mutated one, two, or all three of these sites present in the human MDR1 P-glycoprotein.	Nitrogen	49-50	ATP binding cassette subfamily B member 1	Homo sapiens	123-137
8096511-7	1993	These findings suggest that N-glycosylation contributes to proper routing or stability of P-glycoprotein but not to drug transport per se.	Nitrogen	28-29	ATP binding cassette subfamily B member 1	Homo sapiens	90-104
8387676-9	1993	On the other hand, the microsomal demethylation and cytochrome P-450 content were related to the modification of the nitrogen substituent at C-7.	Nitrogen	117-125	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	52-68
8497191-2	1993	GAP1 activity is regulated by control of synthesis and control of activity in response to the nitrogen source supplied; ammonia and glutamine inactivate GAP1 function while proline and urea allow its maximum expression.	Nitrogen	94-102	amino acid permease GAP1	Saccharomyces cerevisiae S288C	0-4
8392465-0	1993	Leukemia inhibitory factor, interferon gamma and dexamethasone regulate N-glycosylation of alpha 1-protease inhibitor in human hepatoma cells.	Nitrogen	72-73	interferon gamma	Homo sapiens	28-44
8392465-0	1993	Leukemia inhibitory factor, interferon gamma and dexamethasone regulate N-glycosylation of alpha 1-protease inhibitor in human hepatoma cells.	Nitrogen	72-73	serpin family A member 1	Homo sapiens	91-117
8392465-2	1993	So far, interleukin (IL) 6, transforming growth factor beta (TGF beta), tumor necrosis factor alpha (TNF) and IL-1 have been found to control N-glycosylation patterns of APP.	Nitrogen	102-103	tumor necrosis factor	Homo sapiens	72-99
8455597-3	1993	All of the cot2 mutants exhibited a wiener-shaped cellular morphology that was exacerbated by the carbon and nitrogen source but was unaffected by metals.	Nitrogen	109-117	SCF ubiquitin ligase complex subunit GRR1	Saccharomyces cerevisiae S288C	11-15
8497724-7	1993	An augmentation in muscle strength, basal metabolic rate and nitrogen retention by action of GH are expressions of the potential anabolizing effects of this hormone in adult life.	Nitrogen	61-69	growth hormone 1	Homo sapiens	93-95
8097689-7	1993	In this way it could be demonstrated that the major phase I biotransformation reactions for formation of urine excretable metabolites are (i) the cytochrome P-450-catalyzed N-demethylation followed by aromatic ring hydroxylation of the 4-fluoroaniline formed, and (ii) flavin-containing monooxygenase and cytochrome P-450-dependent formation of defluorinated 4-hydroxy-N-methylaniline.	Nitrogen	173-174	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	146-162
7680527-8	1993	Levels of IGF-1 were correlated with nitrogen balance (r = 0.51; p &lt; 0.05) but levels of IGFBP-1 were not.	Nitrogen	37-45	insulin like growth factor 1	Homo sapiens	10-15
8507456-5	1993	We therefore suggest that gp95 is composed of subtypes which differ in N-linked glycosylation.	Nitrogen	71-72	sortilin 1	Homo sapiens	26-30
8511964-3	1993	Transfer of ammonium-glucose pre-grown cells to a medium deprived of nitrogen causes a drastic increase in CPS1 RNA level provided that a readily usable carbon source, such as glucose or fructose, is available to the cells.	Nitrogen	69-77	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	107-111
7681661-3	1993	These results show that cyt.c catalyzed N-demethylation, S-oxidation, and epoxidation in the same manner as P450.	Nitrogen	40-41	cytochrome c, somatic	Homo sapiens	24-29
7681661-6	1993	This immobilized cyt.c catalyzed N-demethylation, S-oxidation, and epoxidation in the same manner as both P450 and free cyt.c, and the activities of these reactions were increased by the immobilization.	Nitrogen	33-34	cytochrome c, somatic	Homo sapiens	17-22
7681661-7	1993	In N-demethylation of N,N-dimethylaniline with cumene hydroperoxide (CHP) catalyzed by cyt.c, the Vmax for CHP was increased by 4.4-fold by the immobilization of the enzyme, while the Km remained unchanged.	Nitrogen	3-4	cytochrome c, somatic	Homo sapiens	87-92
8097689-7	1993	In this way it could be demonstrated that the major phase I biotransformation reactions for formation of urine excretable metabolites are (i) the cytochrome P-450-catalyzed N-demethylation followed by aromatic ring hydroxylation of the 4-fluoroaniline formed, and (ii) flavin-containing monooxygenase and cytochrome P-450-dependent formation of defluorinated 4-hydroxy-N-methylaniline.	Nitrogen	173-174	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	305-321
8095544-1	1993	Chlorpromazine N-oxide, fluphenazine N4"-oxide, prochlorperazine N4"-oxide, sulforidazine N-oxide, and trifluoperazine N4"-oxide were synthesized by oxidation of the designated nitrogen atom in the N-10 side chain of the respective parent drug with 3-chloroperoxybenzoic acid.	Nitrogen	177-185	nuclear receptor subfamily 4 group A member 1	Homo sapiens	198-202
8444251-0	1993	Nitrogen and fat balances in very low birth weight infants fed human milk fortified with human milk or bovine milk protein.	Nitrogen	0-8	casein beta	Bos taurus	110-122
8492300-2	1993	However, it has been shown recently that certain N-unsubstituted organophosphoro-monoamidates (analogues of methamidophos) cause delayed neuropathy even though the inhibited NTE appeared not to have aged (Johnson et al.	Nitrogen	49-50	patatin like phospholipase domain containing 6	Homo sapiens	174-177
8498089-0	1993	Selective induction of rat liver phase II enzymes by N-heterocycle analogues of phenanthrene: a response exhibiting high correlation between UDP-glucuronosyltransferase and microsomal epoxide hydrolase activities.	Nitrogen	53-54	epoxide hydrolase 1	Rattus norvegicus	173-201
8437218-4	1993	Mutants carrying Asn--&gt;Asp mutations at each of the two consensus signals for N-linked glycosylation in the N-terminal domain of SFFVAP-L env (gs1 and gs2), the gs1-2- double mutant, and the gs0 quadruple mutant (mutated at all four signals utilized for N-linked glycosylation in SFFVAP-L env) were made.	Nitrogen	111-112	endogenous retrovirus group W member 1, envelope	Homo sapiens	141-144
8437218-4	1993	Mutants carrying Asn--&gt;Asp mutations at each of the two consensus signals for N-linked glycosylation in the N-terminal domain of SFFVAP-L env (gs1 and gs2), the gs1-2- double mutant, and the gs0 quadruple mutant (mutated at all four signals utilized for N-linked glycosylation in SFFVAP-L env) were made.	Nitrogen	111-112	patatin like phospholipase domain containing 4	Homo sapiens	154-157
8455319-8	1993	The mean daily nitrogen balance was, however, significantly improved in patients receiving intermittent nutrition, and this was accompanied by much higher plasma insulin levels as well as higher plasma amino acid concentrations.	Nitrogen	15-23	insulin	Homo sapiens	162-169
8419363-3	1993	To assess the impact of these carbohydrate chains on CBG production and steroid binding, we mutated a human CBG cDNA so that the six consensus sites for N-glycosylation in the CBG polypeptide were eliminated individually and in various combinations.	Nitrogen	114-115	serpin family A member 6	Homo sapiens	108-111
7679108-9	1993	The predicted dPRP amino acid sequence contains two putative N-linked glycosylation sites and 6 cysteine residues.	Nitrogen	61-62	prp	Drosophila melanogaster	14-18
8439215-8	1993	The improvement in nitrogen retention may be associated with increasing ketone and insulin levels.	Nitrogen	19-27	insulin	Homo sapiens	83-90
8440712-10	1993	It can fully "restore" N-myristoylation of Arf1p.	Nitrogen	23-24	Arf family GTPase ARF1	Saccharomyces cerevisiae S288C	43-48
8094032-10	1993	These results suggest that although PMA-induced ICAM-1 expression is PKC dependent on HS 683 and SK-N-SH cells, the stimulation of ICAM-1 expression by retinoic acid and by IFN-gamma may be due to PKC inactivation at longer time points (24 h), as mimicked by 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride, staurosporine, or PKC depletion by high doses of PMA.	Nitrogen	100-101	proline rich transmembrane protein 2	Homo sapiens	69-72
8427874-1	1993	The mode of binding of N-acylated doxorubicin derivatives to bovine serum albumin (BSA) has been determined by spectrophotometric analysis.	Nitrogen	23-24	albumin	Homo sapiens	68-81
7679407-2	1993	In a previous study comparing the anabolic actions of GH and IGF-I (insulin-like growth factor I), we observed that intravenous infusions of IGF-I (12 micrograms/kg ideal body wt [IBW]/h) attenuated nitrogen wasting to a degree comparable to GH given subcutaneously at a standard dose of 0.05 mg/kg IBW per d. IGF-I, however, had a tendency to cause hypoglycemia.	Nitrogen	199-207	insulin like growth factor 1	Homo sapiens	141-146
7679407-2	1993	In a previous study comparing the anabolic actions of GH and IGF-I (insulin-like growth factor I), we observed that intravenous infusions of IGF-I (12 micrograms/kg ideal body wt [IBW]/h) attenuated nitrogen wasting to a degree comparable to GH given subcutaneously at a standard dose of 0.05 mg/kg IBW per d. IGF-I, however, had a tendency to cause hypoglycemia.	Nitrogen	199-207	insulin like growth factor 1	Homo sapiens	141-146
7679407-4	1993	The GH/IGF-I combination caused significantly greater nitrogen retention (262 +/- 43 mmol/d, mean +/- SD) compared to IGF-I alone (108 +/- 29 mmol/d; P &lt; 0.001).	Nitrogen	54-62	insulin like growth factor 1	Homo sapiens	7-12
8419363-3	1993	To assess the impact of these carbohydrate chains on CBG production and steroid binding, we mutated a human CBG cDNA so that the six consensus sites for N-glycosylation in the CBG polypeptide were eliminated individually and in various combinations.	Nitrogen	114-115	serpin family A member 6	Homo sapiens	108-111
8418900-6	1993	The form lacking N-linked chains had an M(r) (approximately 20,000) similar to that of the unglycosylated form of TIMP in other species.	Nitrogen	17-18	TIMP metallopeptidase inhibitor 1	Homo sapiens	114-118
8424283-9	1993	The higher insulin secretion in response to glucose infusion in the RA group compared to the GA group may indicate an increased peripheral insulin resistance after regional anesthesia or, more likely, this secretion may be beneficial in contributing to improve postoperative nitrogen balance.	Nitrogen	275-283	insulin	Homo sapiens	11-18
7906149-4	1993	Besides the ability of porcine intestinal APH to cleave the first peptide bond in N-protected peptides (Km: 0.8 mM), it is worth stressing that the enzyme was also found to efficiently catalyze the hydrolysis of the isopeptide bond in N-epsilon-Ac-L-Met-L-Lys (Km: 0.7-1.1 mM).	Nitrogen	82-83	acylaminoacyl-peptide hydrolase	Homo sapiens	42-45
8419080-3	1993	Interferon-gamma (IFN-gamma), bacteria, and bacterial products modulated expression of some of the surface markers, induced and/or enhanced respiratory burst, phagocytic activity, secretion of tumour necrosis factor, and tumouricidal activity; in contrast, these cells were not able to generate reactive nitrogen intermediates.	Nitrogen	304-312	interferon gamma	Homo sapiens	0-16
8419080-3	1993	Interferon-gamma (IFN-gamma), bacteria, and bacterial products modulated expression of some of the surface markers, induced and/or enhanced respiratory burst, phagocytic activity, secretion of tumour necrosis factor, and tumouricidal activity; in contrast, these cells were not able to generate reactive nitrogen intermediates.	Nitrogen	304-312	interferon gamma	Homo sapiens	18-27
8518023-1	1993	Recombinant interleukin-2 (rIL-2) can produce impairment of renal function with hypotension, fluid retention, elevated blood urea nitrogen, oliguria and low fractional sodium excretion; these side-effects are a common cause of reduction or interruption of rIL-2 infusion.	Nitrogen	130-138	interleukin 2	Homo sapiens	12-25
8381348-7	1993	Thus, this MyoD/Myf-5-like protein appears to promote sexual differentiation by modulating responses to decreases in cAMP, a part of the nitrogen starvation signal that induces differentiation.	Nitrogen	137-145	myogenic differentiation 1	Homo sapiens	11-15
7507879-6	1993	GH and IGF-I, in pharmacological doses, promote positive nitrogen balance, in both animal models and man.	Nitrogen	57-65	insulin like growth factor 1	Homo sapiens	7-12
8419247-4	1993	RESULTS: TPN prevented loss of body weight, but cachectin-treated animals had reduced nitrogen retention and carcass weight.	Nitrogen	86-94	tumor necrosis factor	Rattus norvegicus	48-57
8419247-8	1993	CONCLUSIONS: In the absence of the effects of anorexia, cachectin reduced nitrogen retention and caused metabolic and multisystem dysfunction, comparable with the effects of clinical sepsis.	Nitrogen	74-82	tumor necrosis factor	Rattus norvegicus	56-65
8300052-10	1993	It appeared that IGF-I was as efficacious as GH in reversing the negative nitrogen balance induced by caloric restriction and that hypoglycemia induced by IGF-I was the major limiting factor.	Nitrogen	74-82	insulin like growth factor 1	Homo sapiens	17-22
8300057-3	1993	When GH is administered to surgical patients, nitrogen retention is regularly seen, and in most situations fast mobilization takes place.	Nitrogen	46-54	growth hormone 1	Homo sapiens	5-7
8468935-5	1993	Comparison of clinical data showed that patients who expressed 5-LO and FLAP had a lower glomerular filtration rate and an increased level of blood urea nitrogen, serum creatinine, and proteinuria.	Nitrogen	153-161	arachidonate 5-lipoxygenase activating protein	Homo sapiens	72-76
8300052-14	1993	The combination of GH/IGF-I was much more potent in improving nitrogen balance.	Nitrogen	62-70	insulin like growth factor 1	Homo sapiens	22-27
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	amino acid permease GAP1	Saccharomyces cerevisiae S288C	50-54
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	proline dehydrogenase	Saccharomyces cerevisiae S288C	56-60
8418811-6	1993	This cDNA corresponds to a peculiar MCP form previously described, which is characterized by the presence of the serine/threonine/proline-rich exon C (STPC) and the cytoplasmic tail known as CYT2, and we conclude that the absence of mature oligosaccharide of the sperm MCP cannot be totally attributed to a defect of N- and O-glycosylation sequences but rather reflects an alteration of the mechanisms of glycosylation in spermatozoa.	Nitrogen	7-8	CD46 molecule	Homo sapiens	36-39
8412792-5	1993	Mutations have been identified that abolish critical thrombin cleavage sites or which generate new N-glycosylation sites.	Nitrogen	99-100	coagulation factor II, thrombin	Homo sapiens	53-61
8423765-13	1993	Both CYP1A2 and CYP3A4 catalyzed N-dealkylation of propafenone, with specific activities of 0.32 pmol/min/pmol of P450 and 0.16 pmol/min/pmol of P450, respectively.	Nitrogen	33-34	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	16-22
8418811-6	1993	This cDNA corresponds to a peculiar MCP form previously described, which is characterized by the presence of the serine/threonine/proline-rich exon C (STPC) and the cytoplasmic tail known as CYT2, and we conclude that the absence of mature oligosaccharide of the sperm MCP cannot be totally attributed to a defect of N- and O-glycosylation sequences but rather reflects an alteration of the mechanisms of glycosylation in spermatozoa.	Nitrogen	7-8	CD46 molecule	Homo sapiens	269-272
8292862-4	1993	Moreover, the early and total postcibal secretions of GIP after gastrectomy were less in the DM-group than in the N-group.	Nitrogen	114-115	gastric inhibitory polypeptide	Homo sapiens	54-57
1447191-8	1992	The ovalbumin/GnTI hybrid molecules in the transfected L cells were N-glycosylated, indicating an N(in)/C(out) membrane orientation, and were localized by immunoperoxidase electron microscopy to one or two cisternae of the medial-Golgi (90% of stained Golgi profiles showed medial-cisternae staining).	Nitrogen	68-69	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	4-13
1334548-4	1992	The RYK-encoded protein bears a transmembrane domain, with a relatively small (183 amino acid) extracellular domain, containing five potential N-linked glycosylation sites.	Nitrogen	143-144	receptor-like tyrosine kinase	Mus musculus	4-7
1447191-8	1992	The ovalbumin/GnTI hybrid molecules in the transfected L cells were N-glycosylated, indicating an N(in)/C(out) membrane orientation, and were localized by immunoperoxidase electron microscopy to one or two cisternae of the medial-Golgi (90% of stained Golgi profiles showed medial-cisternae staining).	Nitrogen	68-69	mannoside acetylglucosaminyltransferase 1	Mus musculus	14-18
1466618-1	1992	The objective of this study was to evaluate the safety and the effect of recombinant exogenous growth hormone (GH) on nitrogen production in patients with severe sepsis.	Nitrogen	118-126	growth hormone 1	Homo sapiens	95-109
1336317-4	1992	); the increase of fractional shortening amounted to 17.4 +/- 4.0 vs. 19.5 +/- 4.8% (NS) in response to 20 ng.kg-1 x min-1 isoprenaline.	Nitrogen	85-87	CD59 molecule (CD59 blood group)	Homo sapiens	117-122
1466618-13	1992	Growth hormone administration reduces nitrogen production and improves nitrogen balance in patients with severe sepsis.	Nitrogen	38-46	growth hormone 1	Homo sapiens	0-14
1466618-13	1992	Growth hormone administration reduces nitrogen production and improves nitrogen balance in patients with severe sepsis.	Nitrogen	71-79	growth hormone 1	Homo sapiens	0-14
1469044-7	1992	Glycosylation studies of Kex1p were consistent with a Golgi location, as Kex1p was progressively N-glycosylated in an MNN1-dependent manner.	Nitrogen	97-98	serine-type carboxypeptidase	Saccharomyces cerevisiae S288C	73-78
1469044-7	1992	Glycosylation studies of Kex1p were consistent with a Golgi location, as Kex1p was progressively N-glycosylated in an MNN1-dependent manner.	Nitrogen	97-98	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	118-122
1487725-1	1992	Secretion of the extracellular Rhizopus carboxyl proteinase (EC 3.4.23.6) by Rhizopus oligosporus is repressed in the presence of low-molecular-mass sources of nitrogen, sulphur and carbon.	Nitrogen	160-168	endogenous retrovirus group K member 25	Homo sapiens	49-59
1494399-8	1992	Despite this difference in initial glucose concentration, normalization of plasma glucose to less than 5 mmol/l with insulin resulted in the same decrease in nitrogen excretion and improvement in glucose oxidation.	Nitrogen	158-166	insulin	Homo sapiens	117-124
1446688-7	1992	Only a portion of recombinant human IL-6 is N-glycosylated.	Nitrogen	44-45	interleukin 6	Homo sapiens	36-40
1431106-8	1992	These results indicate that IFN-gamma plus IL-2-induced tumoricidal activity is dependent upon the metabolism of L-arginine to reactive nitrogen intermediates, and they establish a role for TNF-alpha as a required intermediate for IL-2-dependent NO2- production and tumoricidal activity.	Nitrogen	136-144	interferon gamma	Mus musculus	28-37
1486679-8	1992	Interpreted in the respective pathophysiological contexts results show that: (1) N-linked glycosylation of transferrin is a strictly controlled process, both in the physiological states and in disease.	Nitrogen	81-82	transferrin	Homo sapiens	107-118
1478917-7	1992	The N-linked glycosylation of HuIFN-gamma seemed to occur properly, since treatment of the IFN with N-glycanase resulted in a reduction of molecular weight to 17,000, which corresponds to that calculated from the deduced amino acid sequence of HuIFN-gamma.	Nitrogen	4-5	interferon alpha 1	Homo sapiens	32-35
24178389-7	1992	Treatment of cells with tunicamycin, which inhibits N-glycosylation, and digestion of the (35)S-labelled processing intermediates with endoglycosidase H indicate that beta-1,3-glucanase has a single N-glycan attached to the C-terminal extension.	Nitrogen	52-53	glucan endo-1,3-beta-glucosidase, acidic-like	Nicotiana tabacum	167-185
1334528-0	1992	Influence of DNA repair defects (rad1, rad52) on nitrogen mustard mutagenesis in yeast.	Nitrogen	49-57	ssDNA endodeoxyribonuclease RAD1	Saccharomyces cerevisiae S288C	33-37
1337000-0	1992	Proton, carbon, and nitrogen chemical shifts accurately delineate differences and similarities in secondary structure between the homologous proteins IRAP and IL-1 beta.	Nitrogen	20-28	interleukin 1 beta	Homo sapiens	159-168
1328682-1	1992	The UL16 gene of human cytomegalovirus (HCMV) encodes a predicted translation product with features characteristic of glycoproteins (signal and anchor sequences and eight potential N-linked glycosylation sites).	Nitrogen	181-182	membrane glycoprotein UL16	Human betaherpesvirus 5	4-8
1401897-6	1992	Generation of an expressible cDNA for the mouse C5a receptor was accomplished using the polymerase chain reaction and a sense oligodeoxynucleotide primer which included an initiation codon just 5" to the sequence encoding the N-linked glycosylation site.	Nitrogen	31-32	complement C5a receptor 1	Homo sapiens	48-60
1356991-11	1992	NPR-A size variants were expressed on the cell surface, and heterogeneity was removed by deglycosylation with protein:N-glycosidase F. Our results suggest that the degree of N-linked glycosylation of the NPR-A extracellular domain influences the ability to bind ANP.	Nitrogen	0-1	natriuretic peptide receptor 1	Homo sapiens	204-209
1356501-10	1992	Shifting the subcellular location of GS in transgenic plants apparently altered the nitrogen metabolism and forced the induction in leaves of a native GS gene encoding a cytosolic enzyme.	Nitrogen	84-92	glutamine synthetase	Nicotiana tabacum	37-39
1456441-0	1992	N-glycosylation site mapping of human serotransferrin by serial lectin affinity chromatography, fast atom bombardment-mass spectrometry, and 1H nuclear magnetic resonance spectroscopy.	Nitrogen	0-1	transferrin	Homo sapiens	38-53
1456441-1	1992	This report describes the N-glycosylation site mapping of human serotransferrin (h-STF).	Nitrogen	26-27	transferrin	Homo sapiens	64-79
1431569-7	1992	Despite finding no correlation between serum apoA-IV and triglyceride levels (in either the d less than 1.006 g/ml or 1.006 less than d less than 1.019 g/ml fraction), serum apoA-IV was positively correlated with the renal function parameters of blood urea nitrogen (r = 0.949, P less than 0.001), creatinine (r = 0.952, P less than 0.001), and uric acid (r = 0.903, P less than 0.001).	Nitrogen	257-265	apolipoprotein A4	Rattus norvegicus	174-181
1448117-1	1992	The transforming growth factor-beta 1 (TGF beta 1) and -beta 2 (414) precursors both contain three predicted sites of N-linked glycosylation within their pro regions.	Nitrogen	118-119	transforming growth factor beta 1	Homo sapiens	4-37
1448117-1	1992	The transforming growth factor-beta 1 (TGF beta 1) and -beta 2 (414) precursors both contain three predicted sites of N-linked glycosylation within their pro regions.	Nitrogen	118-119	transforming growth factor beta 1	Homo sapiens	39-62
1448117-5	1992	To determine the importance of N-linked glycosylation to the secretion of TGF beta 1 and -beta 2, site-directed mutagenesis was used to change the Asn residues to Ser residues; the resulting DNAs were transfected into COS cells, and their supernatants were assayed for TGF beta activity.	Nitrogen	31-32	transforming growth factor beta 1	Homo sapiens	74-96
1329681-1	1992	Human growth hormone (GH) has been shown to improve nitrogen balance in surgical patients and to decrease urea production.	Nitrogen	52-60	growth hormone 1	Homo sapiens	6-20
1390633-1	1992	A residue essential for proper closure of the active-site loop in the reaction catalyzed by triosephosphate isomerase is tyrosine-208, the hydroxyl group of which forms a hydrogen bond with the amide nitrogen of alanine-176, a component of the loop.	Nitrogen	200-208	triosephosphate isomerase 1	Homo sapiens	92-117
1519785-3	1992	It has been shown previously that alfentanil clearance is independent of the polymorphic debrisoquine hydroxylase (P-450 2D6), and it is therefore of interest to identify the human cytochrome P-450 enzymes involved in noralfentanil formation, the primary reaction involved in the oxidative N-dealkylation at the piperidine nitrogen.	Nitrogen	323-331	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	181-197
1400872-4	1992	This mutation introduces an additional consensus site for N-glycosylation at this position, and to confirm its utilization we introduced it into a human SHBG complementary DNA.	Nitrogen	58-59	sex hormone binding globulin	Homo sapiens	153-157
1358578-2	1992	Four diaryl compounds containing heterocyclic nitrogen atoms elevated microsomal epoxide hydrolase activity from 2- to 4-fold.	Nitrogen	46-54	epoxide hydrolase 1	Rattus norvegicus	70-98
1510710-8	1992	Negligible metabolism of tolbutamide and S-mephenytoin, substrates of the 2C sub-family, and of p-nitrophenol, a substrate of CYP2E1, was detected, although a trace of the N-deethylated metabolite of lignocaine, thought to be metabolised by CYP3A4, was detected with microsomes from CYP2D6-expressing yeast cells.	Nitrogen	0-1	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	283-289
1500196-11	1992	Moreover, liposomal LPS induced a pronounced immune response in CBA/N mice (defective in B lymphocytes of the LyB-5+ subpopulation).	Nitrogen	68-69	toll-like receptor 4	Mus musculus	20-23
1503519-0	1992	Biosynthetic human growth hormone preserves both muscle protein synthesis and the decrease in muscle-free glutamine, and improves whole-body nitrogen economy after operation.	Nitrogen	141-149	growth hormone 1	Homo sapiens	19-33
1520279-2	1992	Tissue-type plasminogen activator (t-PA) is synthesized in mammalian cells as a mixture of two forms that differ in their extent of N-linked glycosylation.	Nitrogen	132-133	plasminogen activator, tissue type	Homo sapiens	0-33
1520279-2	1992	Tissue-type plasminogen activator (t-PA) is synthesized in mammalian cells as a mixture of two forms that differ in their extent of N-linked glycosylation.	Nitrogen	132-133	plasminogen activator, tissue type	Homo sapiens	35-39
1322273-10	1992	Taken together, these results demonstrate that 1) N-acetylation is an essential requirement for the lactotrope-recruiting activity of alpha MSH and beta END in vitro; and 2) di-ac-alpha MSH and N-ac-beta END can act in a cooperative fashion to recruit additional cells into the PRL-secreting population.	Nitrogen	50-51	prolactin	Rattus norvegicus	278-281
1497619-2	1992	In hepatocytes, dGalF at concentrations of 1 mM or higher completely inhibited N-glycosylation of alpha 1-antitrypsin and alpha 1-acid glycoprotein, whereas 4 mM-2-deoxy-D-galactose (dGal) only slightly impaired N-glycosylation.	Nitrogen	79-80	serpin family A member 1	Homo sapiens	98-117
1497619-2	1992	In hepatocytes, dGalF at concentrations of 1 mM or higher completely inhibited N-glycosylation of alpha 1-antitrypsin and alpha 1-acid glycoprotein, whereas 4 mM-2-deoxy-D-galactose (dGal) only slightly impaired N-glycosylation.	Nitrogen	79-80	beta galactosidase	Drosophila melanogaster	16-20
1497619-3	1992	In monocytes, 1 mM- or 4 mM-dGalF blocked N-glycosylation of alpha 1-antitrypsin and of interleukin-6, while O-glycosylation of interleukin-6 remained unaffected.	Nitrogen	42-43	serpin family A member 1	Homo sapiens	61-80
1636696-6	1992	However, daily urinary obligatory N excretion, which indicated the effect of the low-protein diet and intensive subcutaneous insulin therapy over several days, was increased by 18% in the diabetic group (P less than 0.05).	Nitrogen	34-35	insulin	Homo sapiens	125-132
1421757-1	1992	The human transferrin receptor is a glycoprotein containing three N-linked and one O-linked glycosylation sites.	Nitrogen	66-67	transferrin	Homo sapiens	10-21
1629626-6	1992	We noted two consensus N-linked glycosylation sites in human MC-CPA that are not found in rat and mouse MC-CPA, or in bovine CPA; that at least one of these sites is glycosylated in vivo was verified by N-glycosidase F treatment, lentil lectin binding, and Concanavalin A-Sepharose chromatography.	Nitrogen	23-24	carboxypeptidase A3	Homo sapiens	61-67
1629626-6	1992	We noted two consensus N-linked glycosylation sites in human MC-CPA that are not found in rat and mouse MC-CPA, or in bovine CPA; that at least one of these sites is glycosylated in vivo was verified by N-glycosidase F treatment, lentil lectin binding, and Concanavalin A-Sepharose chromatography.	Nitrogen	23-24	carboxypeptidase A1	Homo sapiens	64-67
1495972-4	1992	Structural analysis of the N-linked outer chain isolated from an mnn1 mnn10 mnt1 strain revealed no alteration in carbohydrate structure compared to the parental mnn1 mnn10 strain.	Nitrogen	27-28	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	65-69
1321738-0	1992	Soluble human interleukin-6-receptor modulates interleukin-6-dependent N-glycosylation of alpha 1-protease inhibitor secreted by HepG2 cells.	Nitrogen	71-72	interleukin 6 receptor	Homo sapiens	14-36
1321738-0	1992	Soluble human interleukin-6-receptor modulates interleukin-6-dependent N-glycosylation of alpha 1-protease inhibitor secreted by HepG2 cells.	Nitrogen	71-72	interleukin 6	Homo sapiens	14-27
1321738-0	1992	Soluble human interleukin-6-receptor modulates interleukin-6-dependent N-glycosylation of alpha 1-protease inhibitor secreted by HepG2 cells.	Nitrogen	71-72	serpin family A member 1	Homo sapiens	90-116
1321738-1	1992	Interleukin-6 (IL-6) induces changes in gene expression and the N-glycosylation pattern of acute-phase proteins in hepatocytes.	Nitrogen	64-65	interleukin 6	Homo sapiens	0-13
1321738-1	1992	Interleukin-6 (IL-6) induces changes in gene expression and the N-glycosylation pattern of acute-phase proteins in hepatocytes.	Nitrogen	64-65	interleukin 6	Homo sapiens	15-19
1321738-3	1992	A genetically engineered gp80-derived soluble human IL-6-receptor (shIL-6-R) significantly enhanced the IL-6 effect on N-glycosylation changes (revealed by reactivity with the lectin-concanavalin A) of a1-protease inhibitor (PI) secreted by human hepatoma cells (HepG2).	Nitrogen	119-120	interleukin 6 receptor	Homo sapiens	25-29
1321738-3	1992	A genetically engineered gp80-derived soluble human IL-6-receptor (shIL-6-R) significantly enhanced the IL-6 effect on N-glycosylation changes (revealed by reactivity with the lectin-concanavalin A) of a1-protease inhibitor (PI) secreted by human hepatoma cells (HepG2).	Nitrogen	119-120	interleukin 6	Homo sapiens	52-56
1321738-3	1992	A genetically engineered gp80-derived soluble human IL-6-receptor (shIL-6-R) significantly enhanced the IL-6 effect on N-glycosylation changes (revealed by reactivity with the lectin-concanavalin A) of a1-protease inhibitor (PI) secreted by human hepatoma cells (HepG2).	Nitrogen	119-120	interleukin 6	Homo sapiens	69-73
1616060-5	1992	SP-B partitioned into chloroform-methanol, which was evaporated under N2.	Nitrogen	70-72	surfactant protein B	Bos taurus	0-4
1619015-9	1992	At the dose of each hormone used, the attenuation of nitrogen wasting produced by infusions of IGF-I was similar in magnitude and timing to that produced by injections of GH.	Nitrogen	53-61	insulin like growth factor 1	Homo sapiens	95-100
1377647-2	1992	Carbohydrates, largely N-linked, contributed to about 18% of the size of the receptor alpha-chain and to about 25% of the beta-chain.	Nitrogen	23-24	Fc gamma receptor and transporter	Homo sapiens	86-97
1610348-3	1992	It has been shown earlier that the IL-6 polypeptide follows the classical secretory pathway where N-linked glycosylation is detectable within the first 15 minutes of labeling with [35S]-methionine and O-linked glycosylation occurs between 15-30 minutes after the start of polypeptide synthesis.	Nitrogen	98-99	interleukin 6	Homo sapiens	35-39
1636958-8	1992	In catabolic conditions, GH is effective in decreasing nitrogen loss, in maintaining nitrogen balance, even with hypocaloric diets, and in increasing protein synthesis and skeletal muscle mass when combined with adequate nutrition.	Nitrogen	55-63	growth hormone 1	Homo sapiens	25-27
1445429-2	1992	CEAnC was shown to be immunochemically identical to CEA, but to differ substantially with regard to the amino acid and sugar composition, and structure of the sugar moiety, possibly containing non only N-, but also O-glycosyl carbohydrate chains.	Nitrogen	202-203	CEA cell adhesion molecule 3	Homo sapiens	0-3
1619015-5	1992	IGF-I improved nitrogen balance from -236 +/- 45 mmol/day (+/- SE) during diet alone, to -65 +/- 40 mmol/day (P less than 0.001) during the last 4 days of IGF-I infusion.	Nitrogen	15-23	insulin like growth factor 1	Homo sapiens	0-5
1388517-1	1992	The effects of resorcinolic lipids (5-n-alk(en)ylresorcinols) isolated from cereal grains on the phospholipase A2 catalyzed hydrolysis of phospholipid vesicles were examined.	Nitrogen	22-23	phospholipase A2 group IB	Homo sapiens	97-113
1444161-2	1992	After 6 months a significant reduction of SBP and DBP (p &lt; 0.001), with improvement of creatinine clearance and with no adverse effects on ECG, heart rate and routine laboratory tests test, was observed in 3 patients treated with N 20 mg x 2/d + E 10 mg/d + A 50 mg/d and in 8 patients treated with N 20 mg x 3 + E 10 mg x 2, + A 50 mg x 2.	Nitrogen	233-234	D-box binding PAR bZIP transcription factor	Homo sapiens	50-53
1599422-2	1992	Mouse macrophages activated by interferon-gamma kill intracellular Leishmania by a process that depends on the generation of L-arginine-derived nitrogen oxidation products.	Nitrogen	144-152	interferon gamma	Mus musculus	31-47
1636958-8	1992	In catabolic conditions, GH is effective in decreasing nitrogen loss, in maintaining nitrogen balance, even with hypocaloric diets, and in increasing protein synthesis and skeletal muscle mass when combined with adequate nutrition.	Nitrogen	85-93	growth hormone 1	Homo sapiens	25-27
1599422-11	1992	These results indicate that the ionophore-induced leishmanicidal activity occurs through a process similar to that evoked by interferon-gamma, i.e. the production of L-arginine-derived nitrogen oxidation products.	Nitrogen	185-193	interferon gamma	Mus musculus	125-141
1382725-10	1992	The evidence was obtained that so called mucin "link protein", 118 kDa glycopeptide, is a N-glycosylated fragment of fibronectin, whereas the supposedly native undegraded mucin isolated by Carlstedt et al.	Nitrogen	90-91	fibronectin 1	Homo sapiens	117-128
1630156-4	1992	In human liver microsomes, the glucocorticoid-inducible cytochrome P-450IIIA, CYP3A, catalyzes the N-demethylation of erythromycin.	Nitrogen	99-100	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	78-83
1581354-2	1992	All encoded a splice variant of the PSG-11 gene designated PSG-11s, which can encode a secreted protein of 426 amino acids, containing six potential N-linked glycosylation sites, with a domain structure L-N-AI-AII-BII-C. Minor differences between the four clones sequenced included a restriction site polymorphic for ApaI that may differentiate between alleles of the PSG-11 gene.	Nitrogen	149-150	pregnancy specific beta-1-glycoprotein 11	Homo sapiens	36-42
24178068-5	1992	In "effective", nitrogen-fixing nodules, colonized by wild-type bacteria, chitinase and peroxidase activities had low levels in the central infected zone and were enhanced primarily in the nodule cortex.	Nitrogen	16-24	peroxidase	Glycine max	88-98
1587858-3	1992	Sequence analysis of this clone showed that (a) it contained the entire translated region of PGG/HS and (b) it displayed an in-frame splicing of the last 111 base pairs encoded by exon 9, which resulted in the elimination of the N-glycosylation site at residue 409.	Nitrogen	229-230	prostaglandin-endoperoxide synthase 1	Homo sapiens	93-99
1587858-6	1992	The elimination of one of the four N-glycosylation sites by the alternative splicing of exon 9 and the differential regulation of this process by relevant cytokines and growth factors may represent a mechanism for the regulation of PGG/HS enzymatic activity under physiological or pathological conditions.	Nitrogen	35-36	prostaglandin-endoperoxide synthase 1	Homo sapiens	232-238
1581354-2	1992	All encoded a splice variant of the PSG-11 gene designated PSG-11s, which can encode a secreted protein of 426 amino acids, containing six potential N-linked glycosylation sites, with a domain structure L-N-AI-AII-BII-C. Minor differences between the four clones sequenced included a restriction site polymorphic for ApaI that may differentiate between alleles of the PSG-11 gene.	Nitrogen	149-150	pregnancy specific beta-1-glycoprotein 11	Homo sapiens	59-65
1373603-8	1992	The enzyme preparation also specifically catalysed the transfer of N-acetylgalactosaminyl residues from UDP-N-acetyl[1-3H]galactosamine to bovine submaxillary mucin core protein and to myelin basic protein.	Nitrogen	67-68	myelin basic protein	Bos taurus	185-205
1526365-10	1992	Furthermore, Ca2+ channel blockers markedly inhibited increases in the serum urea nitrogen and creatinine concentrations and development of the tubular necrosis and the lesions of the arterial walls, which were induced by DQ-2556.	Nitrogen	82-90	carbonic anhydrase 2	Rattus norvegicus	13-16
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Nitrogen	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	105-110
1406613-4	1992	The rate constant of the reaction of nitrogen mustard with guanine in the polynucleotide (k = 9,0.10(-3) min-1) is about one-third of that for the fixation of Z-form of the (dG-dC)-insert in the plasmid (k1 = 2,8.10(-2) min-1) which is attributed to a greater rate of formation of diguanyl derivative in the opposite DNA chains.	Nitrogen	37-45	CD59 molecule (CD59 blood group)	Homo sapiens	220-225
1385648-4	1992	IFN-gamma-induced PM larvicidal activity was dependent on live cells, energy, as well as protein synthesis, and appeared to be mediated by toxic nitrogen metabolites.	Nitrogen	145-153	interferon gamma	Mus musculus	0-9
1314822-13	1992	There is a minimal lag phase under an atmosphere of N2 because ferro-MPO would be rapidly oxidized by benzoquinone, without formation of compound III.	Nitrogen	52-54	myeloperoxidase	Homo sapiens	69-72
1626915-4	1992	Statistically significant (P less than 0.05) positive correlation occurred between nitrogen balance (range, -7.5 to +11.0 g/day) and IGF-1 or pre-albumin.	Nitrogen	83-91	insulin like growth factor 1	Homo sapiens	133-138
1541823-12	1992	The results of this study indicate that the mechanism of action of IFN-gamma on the resistance of macrophages to LVS growth is related, at least in part, to the production of reactive nitrogen metabolites.	Nitrogen	184-192	interferon gamma	Mus musculus	67-76
1626915-5	1992	Correlation between nitrogen balance and IGF-1 is preserved during the acute phase response to tissue injury when C-reactive protein (CRP) varies in the range 40-248 mg/L.	Nitrogen	20-28	insulin like growth factor 1	Homo sapiens	41-46
1626915-5	1992	Correlation between nitrogen balance and IGF-1 is preserved during the acute phase response to tissue injury when C-reactive protein (CRP) varies in the range 40-248 mg/L.	Nitrogen	20-28	C-reactive protein	Homo sapiens	114-132
1626915-5	1992	Correlation between nitrogen balance and IGF-1 is preserved during the acute phase response to tissue injury when C-reactive protein (CRP) varies in the range 40-248 mg/L.	Nitrogen	20-28	C-reactive protein	Homo sapiens	134-137
1564000-9	1992	Proportions of body N retention not accounted for by net total splanchnic AAN release increased with GRF treatment.	Nitrogen	20-21	growth hormone releasing hormone	Homo sapiens	101-104
1564001-5	1992	Treatment with GRF increased (P less than .01) N retention by decreasing (P less than .05) fecal and urinary excretion: N retention averaged 10.0 and 20.8 g/d at low intake and 25.9 and 46.7 g/d at high intake for control- and GRF-treated steers, respectively.	Nitrogen	47-48	growth hormone releasing hormone	Homo sapiens	15-18
1315922-9	1992	A role for cAMP has been suggested in nitrogen fixation.	Nitrogen	38-46	cathelicidin antimicrobial peptide	Homo sapiens	11-15
1577665-1	1992	Novel analogs of (9R)-9-deoxo-9-(N,N-dimethylamino)erythromycin A bearing N-alkylamino substituents at the C-21 position were synthesized.	Nitrogen	0-1	TBL1X/Y related 1	Homo sapiens	107-111
1613059-3	1992	The results showed that in the colchicine series substitution at the nitrogen in position C7 decreases the lipophilicity, whereas in the colchiceinamide series substitution at the nitrogen in position C10 increases lipophilicity.	Nitrogen	180-188	homeobox C10	Homo sapiens	201-204
1540641-10	1992	Partition ratios for the pair of N-methyl isomers with bovine MAO B were calculated to be 1640 (E-isomer) and 1430 (Z-isomer).	Nitrogen	33-34	monoamine oxidase B	Bos taurus	62-67
1371917-1	1992	Murine macrophages activated by interferon-gamma and lipopolysaccharide become leishmanicidal through a process involving L-arginine-derived nitrogen oxidation products.	Nitrogen	141-149	interferon gamma	Mus musculus	32-48
1540178-5	1992	Preincubation of the transfected cells with the N-glycosylation inhibitor tunicamycin resulted in the conversion of the 47 kDa VEGF homodimer into a smaller, deglycosylated form of 42 kDa.	Nitrogen	48-49	vascular endothelial growth factor A	Homo sapiens	127-131
1531364-5	1992	Examination of N-substituted analogues of spiperone may provide insights into the topography of the antagonist binding region of the 5-HT2 receptor.	Nitrogen	15-16	5-hydroxytryptamine receptor 2A	Homo sapiens	133-147
1531184-0	1992	NIT2, the nitrogen regulatory protein of Neurospora crassa, binds upstream of nia, the tomato nitrate reductase gene, in vitro.	Nitrogen	10-18	nitrate reductase [NADH]	Solanum lycopersicum	94-111
1363462-9	1992	The results suggest that N-phthalidylation, N-hydroxymethylation and N-acyloxymethylation of pyroglutamyl peptides may be useful prodrug approaches to protect such peptides against cleavage by pyroglutamyl aminopeptidase and hence to improve their delivery characteristics.	Nitrogen	25-26	carboxypeptidase Q	Homo sapiens	206-220
1531184-1	1992	The nit-2 gene of Neurospora crassa encodes a trans-acting regulatory protein that activates the expression of a number of structural genes which code for nitrogen catabolic enzymes, including nitrate reductase.	Nitrogen	155-163	nitrate reductase [NADH]	Solanum lycopersicum	193-210
1306804-6	1992	The N-demethylation pathway to 3-methoxymorphinan is accessory and is dependent on the CYP3A subfamily.	Nitrogen	4-5	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	87-92
1292979-2	1992	Administering growth hormone to normal volunteers who have been made catabolic by caloric restriction improves the nitrogen balance.	Nitrogen	115-123	growth hormone 1	Homo sapiens	14-28
1346997-0	1992	Characterization of the cytochrome P-450 gene family responsible for the N-dealkylation of the ergot alkaloid CQA 206-291 in humans.	Nitrogen	73-74	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	24-40
1292979-3	1992	The studies described illustrate that administration of somatomedin-C (IGF-I) to catabolic normal volunteers also results in improved nitrogen balance and, unlike growth hormone, does not induce insulin resistance.	Nitrogen	134-142	insulin like growth factor 1	Homo sapiens	56-69
1292979-3	1992	The studies described illustrate that administration of somatomedin-C (IGF-I) to catabolic normal volunteers also results in improved nitrogen balance and, unlike growth hormone, does not induce insulin resistance.	Nitrogen	134-142	insulin like growth factor 1	Homo sapiens	71-76
1634326-4	1992	In comparison with [Leu5]enkephalin, all three N-glycoconjugates showed higher potency in the guinea pig ileum assay and lower potency in the mouse vas deferens assay, indicating a decrease in delta opioid receptor selectivity.	Nitrogen	47-48	tripartite motif-containing 13	Mus musculus	20-24
1490663-0	1992	Stimulation of nitrogen and whole-body protein metabolism in growth hormone-deficient children by recombinant human growth hormone: relationship to growth.	Nitrogen	15-23	growth hormone 1	Homo sapiens	116-130
1490663-1	1992	The effect of a mammalian-cell-derived recombinant human growth hormone (rhGH) on nitrogen and whole-body protein metabolism was assessed in 12 children with complete growth hormone (GH) deficiency.	Nitrogen	82-90	growth hormone 1	Homo sapiens	57-71
1345910-1	1992	During nitrogen-limited growth, transcription of glnA, which codes for glutamine synthetase, requires sigma 54-RNA polymerase and the phosphorylated from the nitrogen regulator I (NRI; also called NtrC).	Nitrogen	7-15	glutamate-ammonia ligase	Homo sapiens	71-91
1345910-1	1992	During nitrogen-limited growth, transcription of glnA, which codes for glutamine synthetase, requires sigma 54-RNA polymerase and the phosphorylated from the nitrogen regulator I (NRI; also called NtrC).	Nitrogen	158-166	glutamate-ammonia ligase	Homo sapiens	71-91
1345910-4	1992	Our results also suggest that the negative effect of a high concentration of NRI on glnA expression is a major determinant of the level of glutamine synthetase activity in nitrogen-limited cells of a wild-type strain.	Nitrogen	172-180	glutamate-ammonia ligase	Homo sapiens	139-159
1755859-1	1991	Site directed mutagenesis of the rat ovarian luteinizing hormone (LH) receptor cDNA was performed at each of the six potential N-linked glycosylation sites to determine the effect of putative carbohydrate chains on the activity of the membrane receptor.	Nitrogen	81-82	luteinizing hormone/choriogonadotropin receptor	Rattus norvegicus	45-78
1378467-7	1992	The evidence was obtained that so-called mucin "link protein", a 118-kDa glycopeptide, is a N-glycosylated fragment of fibronectin, whereas the supposedly native undergraded mucin isolated by Carlstedt et al.	Nitrogen	92-93	fibronectin 1	Homo sapiens	119-130
1761560-0	1991	The role of N-glycosylation of GLUT1 for glucose transport activity.	Nitrogen	12-13	solute carrier family 2, facilitated glucose transporter member 1	Cricetulus griseus	31-36
1761560-1	1991	To elucidate a functional role of N-glycosylation in glucose transporters, we introduced oligonucleotide-directed mutagenesis in GLUT1 cDNA to remove the possible site for N-linked glycosylation.	Nitrogen	34-35	solute carrier family 2, facilitated glucose transporter member 1	Cricetulus griseus	129-134
1761560-6	1991	These observations strongly suggest that 1) N-glycosylation of GLUT1 glucose transporter is only on Asn 45 and 2) N-glycosylation plays an important role in maintaining a structure of glucose transporter with high affinity for glucose, thus, with high transport activity.	Nitrogen	44-45	solute carrier family 2, facilitated glucose transporter member 1	Cricetulus griseus	63-68
1761560-6	1991	These observations strongly suggest that 1) N-glycosylation of GLUT1 glucose transporter is only on Asn 45 and 2) N-glycosylation plays an important role in maintaining a structure of glucose transporter with high affinity for glucose, thus, with high transport activity.	Nitrogen	114-115	solute carrier family 2, facilitated glucose transporter member 1	Cricetulus griseus	63-68
1959624-3	1991	In the presence of linoleic acid, the level of n-hexanal produced was highest in the lipoxygenase-1, -3 double deficient line, followed by the lipoxygenase-2, -3 double deficient, wild type, and lipoxygenase-1, -2, -3 triple deficient lines in that order, and lowest in the lipoxygenase-1, -2 double deficient line.	Nitrogen	1-2	seed linoleate 13S-lipoxygenase-1	Glycine max	85-103
1722319-7	1991	Analysis of the deduced amino acid sequence suggests that CHIP28 protein contains six bilayer-spanning domains, two exofacial potential N-glycosylation sites, and intracellular N and C termini.	Nitrogen	136-137	aquaporin 1 (Colton blood group)	Homo sapiens	58-64
1777593-1	1991	Administration of recombinant human growth hormone stimulates protein synthesis, decreases urea generation, and improves nitrogen balance in individuals with normal renal function.	Nitrogen	121-129	growth hormone 1	Homo sapiens	36-50
1793613-3	1991	Insulin-mediated decrease in serum potassium (K+) and in blood urea nitrogen (BUN) concentration was evaluated in 20 adolescents with IDDM and 10 matched controls during a 3-h hyperinsulinemic (1.7 mU/kg/min)-euglycemic clamp study.	Nitrogen	68-76	insulin	Homo sapiens	0-7
1934374-9	1991	At these four sites, CGRP resulted in dilatation by 17.0 +/- 5.6%, 15.3 +/- 12.1% (NS), 7.6 +/- 5.4% (NS), and 15.9 +/- 7.8%, respectively.	Nitrogen	83-85	calcitonin related polypeptide alpha	Homo sapiens	21-25
1934374-9	1991	At these four sites, CGRP resulted in dilatation by 17.0 +/- 5.6%, 15.3 +/- 12.1% (NS), 7.6 +/- 5.4% (NS), and 15.9 +/- 7.8%, respectively.	Nitrogen	102-104	calcitonin related polypeptide alpha	Homo sapiens	21-25
1761807-3	1991	Insulin responsiveness was similar in N and in HC, but it was 23% greater in CHOL (p less than 0.001).	Nitrogen	38-39	insulin	Homo sapiens	0-7
1657925-0	1991	Effects of site-directed removal of N-glycosylation sites in human erythropoietin on its production and biological properties.	Nitrogen	36-37	erythropoietin	Homo sapiens	67-81
1657925-5	1991	The elimination of all three N-glycosylation sites decreased Epo production to 10% of that of the wild-type Epo.	Nitrogen	29-30	erythropoietin	Homo sapiens	61-64
1657925-5	1991	The elimination of all three N-glycosylation sites decreased Epo production to 10% of that of the wild-type Epo.	Nitrogen	29-30	erythropoietin	Homo sapiens	108-111
1657925-7	1991	Removal of N-glycosylation sites changed affinity of Epo to the receptor.	Nitrogen	11-12	erythropoietin	Homo sapiens	53-56
1657925-8	1991	The in vitro activity of Epo that lost all N-glycosylation sites was comparable with that of the wild-type Epo, while the in vivo activity severely decreased.	Nitrogen	43-44	erythropoietin	Homo sapiens	25-28
1657925-9	1991	These results indicate that N-linked sugars of Epo have two major functions; N-linked sugars are important for 1) proper biosynthesis and/or secretion and 2) expression of the in vivo activity probably by enhancing survival in the circulation.	Nitrogen	28-29	erythropoietin	Homo sapiens	47-50
1924389-3	1991	Computer analyses reveal a putative signal peptide and two probable N-glycosylation sites in the PlGF protein, one of which is also conserved in human VPF.	Nitrogen	68-69	placental growth factor	Homo sapiens	97-101
1717459-8	1991	The binding sites displayed an absolute requirement for an N-myristoyl moiety and a strong preference for pp60c-src amino-terminal sequences.	Nitrogen	59-60	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	112-115
1680848-1	1991	Several approaches were used to study the role of GroEL, the prototype chaperonin, in the nitrogen fixation (nif) system.	Nitrogen	90-98	GroEL	Escherichia coli	50-55
1761807-6	1991	Insulin clearance rate (ICR) was significantly (p less than 0.005) decreased in HC (1060 +/- 80, 996 +/- 95 and 776 +/- 128 ml sq m-1 ml-1 in N, CHOL and HC respectively.	Nitrogen	142-143	insulin	Homo sapiens	0-7
1655531-0	1991	Differential glycosylation of N-POMC1-77 regulates the production of gamma 3-MSH by purified pro-opiomelanocortin converting enzyme.	Nitrogen	30-31	proopiomelanocortin	Bos taurus	93-113
1654090-5	1991	Electron nuclear double resonance (ENDOR) measurements on the VO(2+)-apoferritin complex showed couplings from two nitrogen nuclei, tentatively ascribed to the N1 and N3 nitrogens of the imidazole ligand of histidine.	Nitrogen	115-123	ferritin heavy chain	Equus caballus	69-80
1654278-0	1991	Zn(2+)-induced deprotonation of a peptide nitrogen in angiotensin I.	Nitrogen	42-50	angiotensinogen	Homo sapiens	54-67
1654090-5	1991	Electron nuclear double resonance (ENDOR) measurements on the VO(2+)-apoferritin complex showed couplings from two nitrogen nuclei, tentatively ascribed to the N1 and N3 nitrogens of the imidazole ligand of histidine.	Nitrogen	170-179	ferritin heavy chain	Equus caballus	69-80
1723642-6	1991	In this report, we demonstrate that VC1.1 recognizes an N-linked carbohydrate group that is attached to myelin-associated glycoprotein and N-CAM.	Nitrogen	56-57	myelin-associated glycoprotein	Rattus norvegicus	104-134
1653602-9	1991	The CGRP receptor is N-glycosylated.	Nitrogen	21-22	calcitonin related polypeptide alpha	Homo sapiens	4-8
1916277-0	1991	Sequences of two adjacent genes, one (DAL2) encoding allantoicase and another (DCG1) sensitive to nitrogen-catabolite repression in Saccharomyces cerevisiae.	Nitrogen	98-106	allantoicase	Saccharomyces cerevisiae S288C	38-42
1880417-0	1991	Alpha-chains of IgM and IgD antigen receptor complexes are differentially N-glycosylated MB-1-related molecules.	Nitrogen	74-75	CD79a molecule	Homo sapiens	89-93
1831224-4	1991	Although CD24 is structurally similar to M1/69-J11d, and the two Ag appear to have a common genetic ancestry, the homology of CD24 to the M1/69-J11d Ag is confined to a small cluster of amino acids comprising potential N-linked glycosylation sites.	Nitrogen	219-220	CD24 molecule	Homo sapiens	9-13
1831224-4	1991	Although CD24 is structurally similar to M1/69-J11d, and the two Ag appear to have a common genetic ancestry, the homology of CD24 to the M1/69-J11d Ag is confined to a small cluster of amino acids comprising potential N-linked glycosylation sites.	Nitrogen	219-220	CD24 molecule	Homo sapiens	126-130
1907134-1	1991	Evidence based on optimal pH, thermal stability, and enzyme inhibition data suggests that the NADPH-dependent microsomal N-oxidation of the pyrrolizidine alkaloid senecionine is carried out largely by flavin-containing monooxygenase in guinea pig liver, lung, and kidney.	Nitrogen	94-95	flavin-containing monooxygenase	Cavia porcellus	201-232
1859403-3	1991	The predicted amino acid sequences of LGP85 consisted of 478 amino acid residues (Mr.54,090) and the protein has 11 potential N-glycosylation sites.	Nitrogen	126-127	scavenger receptor class B, member 2	Rattus norvegicus	38-43
1742352-1	1991	The turnover of EF-Tu.GTP on poly-U programmed ribosomes was measured both in the presence and in the absence of N-acetylated Phe-tRNA(Phe) at the P-site.	Nitrogen	113-114	Tu translation elongation factor, mitochondrial	Homo sapiens	16-21
1895488-3	1991	Statistically significant correlations were found between nitrogen balance and serum prealbumin, retinol-binding protein, and transferrin.	Nitrogen	58-66	transferrin	Homo sapiens	126-137
1905642-9	1991	Consistent with the conclusion that endogenously produced TNF-alpha accounts for the synergism of IL 4 with IFN-gamma is the finding that N omega-monomethyl-L-arginine, an inhibitor of the L-arginine-dependent generation of microbicidal nitrogen intermediates, totally blocked the M phi activation induced by IFN-gamma combined with IL 4 as well as by IFN-gamma combined with TNF-alpha.	Nitrogen	237-245	tumor necrosis factor	Mus musculus	58-67
1887520-5	1991	The "susceptibility" for the generation of a persistent bubble at any time can be defined as the reciprocal of the difference, at that time, between partial pressure of the nitrogen in tissue and in a spherical bubble of the size that is characteristic of the nucleation process or nucleus; susceptibility is less when ascent is slow because PN2 in bubbles stays high while washout removes N2 from the tissue.	Nitrogen	173-181	amyloid beta precursor protein	Homo sapiens	342-345
1874449-4	1991	The cTR has several highly conserved regions within its extracellular domain, including those flanking the putative N-glycosylation sites.	Nitrogen	116-117	calcitonin receptor	Homo sapiens	4-7
2039545-11	1991	All of these findings suggest that 1-substituted heteroaromatic compounds having two or more nitrogen atoms are likely to be required for inducing cytochrome P450.	Nitrogen	93-101	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	147-162
16668258-6	1991	Treatment of nodulated plants with fixed nitrogen (urea) led to concomitant decreases in acetylene reduction activity, in leghemoglobin content, and in activities of ASC peroxidase, DHA reductase, and GSSG reductase.	Nitrogen	41-49	peroxidase	Glycine max	170-180
20700226-1	1991	X transitions in Hgl caused by collisions of N(2)(+) -CO(+) ions with Hgl(2) molecules.	Nitrogen	45-52	lipase F, gastric type	Homo sapiens	17-20
1828762-10	1991	Further analyses using glycoprotein synthesis inhibitors showed that N-linked processing of the alpha-chain, especially glucose removal by glucosidase I and II (whose activities are inhibited by deoxynojirimycin), appeared to be required for the expression onto the cell surface although the beta-chain expression was little affected by their inhibitors.	Nitrogen	69-70	Fc gamma receptor and transporter	Homo sapiens	96-107
1828762-10	1991	Further analyses using glycoprotein synthesis inhibitors showed that N-linked processing of the alpha-chain, especially glucose removal by glucosidase I and II (whose activities are inhibited by deoxynojirimycin), appeared to be required for the expression onto the cell surface although the beta-chain expression was little affected by their inhibitors.	Nitrogen	69-70	mannosyl-oligosaccharide glucosidase	Homo sapiens	139-159
2046401-7	1991	Inhibition of N-linked glycosylation prevents exit of both the wild-type and the truncated vWF from the endoplasmic reticulum.	Nitrogen	14-15	von Willebrand factor	Homo sapiens	91-94
2036835-6	1991	Nitrogen balance also improved during GH treatment (+1.6 +/- 0.7 g/day on diet alone vs +3.8 +/- 0.5 g/day on diet plus GH, p less than 0.02).	Nitrogen	0-8	growth hormone 1	Homo sapiens	38-40
2036835-6	1991	Nitrogen balance also improved during GH treatment (+1.6 +/- 0.7 g/day on diet alone vs +3.8 +/- 0.5 g/day on diet plus GH, p less than 0.02).	Nitrogen	0-8	growth hormone 1	Homo sapiens	120-122
1709881-8	1991	A transcriptional activation of CPS1 occurs when cells grow on a substrate of carboxy-peptidase yscS as sole nitrogen source.	Nitrogen	109-117	Gly-Xaa carboxypeptidase	Saccharomyces cerevisiae S288C	32-36
2033081-1	1991	Natural human interleukin-6 (IL-6) characterized under completely denaturing conditions consists of a set of differentially modified phosphoglycoproteins of molecular mass in the range from 23 to 30 kDa ("25-kDa" O-glycosylated species and "30-kDa" O- and N-glycosylated species).	Nitrogen	0-1	interleukin 6	Homo sapiens	14-27
2033081-1	1991	Natural human interleukin-6 (IL-6) characterized under completely denaturing conditions consists of a set of differentially modified phosphoglycoproteins of molecular mass in the range from 23 to 30 kDa ("25-kDa" O-glycosylated species and "30-kDa" O- and N-glycosylated species).	Nitrogen	0-1	interleukin 6	Homo sapiens	29-33
2033081-2	1991	The 25-kDa O-glycosylated IL-6 (which contains only Ser- or Thr-GalNAc-Gal-NeuNAc and thus should not bind wheat germ or lentil lectins) bound to and was eluted from a wheat germ lectin affinity column by GlcNAc and from a lentil lectin affinity column by methyl-alpha-D-Man suggesting that the 25-kDa IL-6 species formed heteromeric complexes with the N-glycosylated 30-kDa IL-6.	Nitrogen	67-68	interleukin 6	Homo sapiens	26-30
1853466-3	1991	Nitrogen bubbles activated human complement as measured by generation of the fluid-phase, complement-split product C5a des Arg.	Nitrogen	0-8	complement C5a receptor 1	Homo sapiens	115-118
1883960-4	1991	Amino acid sequencing revealed that the major amino terminus in the fibroblast-derived 23- to 25-kD O-glycosylated IL-6 was at Ala28 whereas the major amino terminus in the 28- to 30-kD N- and O-glycosylated IL-6 was at Val30, suggesting that targeting of newly synthesized IL-6 polypeptides into the two different processing pathways in fibroblasts may be keyed to differences in the signal peptide cleavage site.	Nitrogen	186-187	interleukin 6	Homo sapiens	115-119
1883960-5	1991	Unexpectedly, IL-6 "constitutively" secreted by the Epstein-Barr virus (EBV)-infected human and primate (tamarin) B-cell lines designated sfBJAB and sfBT, respectively, consisted of a major apparently unglycosylated 21-kD species and a minor 25-kD N-glycosylated species.	Nitrogen	248-249	interleukin 6	Homo sapiens	14-18
1686442-2	1991	Helodermin stimulated the somatostatin release in a concentration-dependent manner during the first (controls, 100%; 1 pmol/L, 113%, ns; 10 pmol/L, 175%, p less than 0.05; 100 pmol/L, 233%, p less than 0.05) and the second secretion phases (controls, 100%; 1 pmol/L, 117%, ns; 10 pmol/L, 210%, p less than 0.05; 100 pmol/L, 362%, p less than 0.05).	Nitrogen	133-135	somatostatin	Rattus norvegicus	26-38
2016320-4	1991	Structural characterization of CD6 revealed that it contained intrachain disulfide bonds, was N-glycosylated, and in activated cells was phosphorylated on serine.	Nitrogen	94-95	CD6 molecule	Homo sapiens	31-34
1901040-6	1991	Very high levels of glutamate dehydrogenase were found in this archaebacterium which suggests that the conversion of 2-oxoglutarate and ammonia to glutamate is of central importance to the nitrogen metabolism in this bacterium.	Nitrogen	189-197	Gfo/Idh/MocA family oxidoreductase	Saccharolobus solfataricus	30-43
1706753-4	1991	In addition, novel laboratory mutants were obtained containing substitutions in the HA1 subunit that had not been reported previously for H3 subtype viruses, either natural variants or laboratory mutants, at residues: HA1 62 Ile----Arg; HA1 165 Asn----Ser (resulting in the loss of a N-glycosylation site); and HA1 273 Pro----Leu.	Nitrogen	284-285	Rho GTPase activating protein 45	Mus musculus	84-87
1850168-4	1991	Similarly, inhibition of N-linked glycosylation by tunicamycin during viral infection of cell monolayers altered their ability to induce IFN alpha.	Nitrogen	25-26	interferon alpha 1	Homo sapiens	137-146
2003276-4	1991	A structural feature common to these compounds is the N-methyl determinant of the pyrrolidine ring which may be important in binding to the AChE.	Nitrogen	54-55	acetylcholinesterase (Cartwright blood group)	Homo sapiens	140-144
2003558-5	1991	In contrast, N-acetylated beta-endorphin did not stimulate germination.	Nitrogen	13-14	proopiomelanocortin	Homo sapiens	26-40
2000045-0	1991	Growth hormone improves muscle protein metabolism and whole body nitrogen economy in man during a hyponitrogenous diet.	Nitrogen	65-73	growth hormone 1	Homo sapiens	0-14
1672608-10	1991	These data indicate that the major modification of P-gp is N-linked glycosylation.	Nitrogen	59-60	ATP binding cassette subfamily B member 1	Homo sapiens	51-55
1664258-0	1991	N-Chlorination and oxidation of procainamide by myeloperoxidase: toxicological implications.	Nitrogen	0-1	myeloperoxidase	Homo sapiens	48-63
2005335-9	1991	Urinary nitrogen retention occurred only in the growth hormone treated subjects (P less than 0.05).	Nitrogen	8-16	growth hormone 1	Homo sapiens	48-62
1993171-10	1991	Sequence analysis of the peptides containing the third and fifth cysteines of human IL-4 also demonstrated that only one of the potential N-glycosylation sites is used by C127 mammary tumor cells.	Nitrogen	138-139	interleukin 4	Homo sapiens	84-88
1862663-19	1991	After 4 h the concn of AABP and ABP was 27-35 mmol/ml, indicating a dynamic equilibrium between N-deacetylation of AABP and acetylation of ABP.	Nitrogen	96-97	glutamate receptor interacting protein 2	Rattus norvegicus	23-35
1847387-3	1991	This chimera also contains a modification to prevent high mannose type N-linked glycosylation on kringle 1 of t-PA.	Nitrogen	71-72	plasminogen activator, tissue type	Homo sapiens	110-114
1995196-2	1991	Both 2-N- and 5-substituted MeIQx metabolites were recognized by antibodies AIA-2 and AIA-11, while antibodies AIA-1 and AIA-12 bound N-substituted metabolites only.	Nitrogen	7-8	Adjuvant induced arthritis QTL 2	Rattus norvegicus	76-81
1991164-8	1991	For example, compared with normal control values (N), femoral and splenic CFU-s numbers in IL-6-treated mice 17 days postirradiation were 27% N and 136% N versus 2% N and 10% N in saline-treated mice.	Nitrogen	142-143	interleukin 6	Mus musculus	91-95
1670761-1	1991	Enzymatic sulfation of N-hydroxylated arylamines by mammalian hepatic cytosol sulfotransferases (AST; EC 2.8.2.1) is an important metabolic step which generates ultimate carcinogens.	Nitrogen	23-24	solute carrier family 17 member 5	Homo sapiens	97-100
1990286-0	1991	The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases.	Nitrogen	106-114	glutathione peroxidase	Saccharomyces cerevisiae S288C	4-8
1990286-5	1991	Active URE2 gene product was required for the inactivation of glutamine synthetase upon addition of glutamine to cells growing with glutamate as the source of nitrogen.	Nitrogen	159-167	glutathione peroxidase	Saccharomyces cerevisiae S288C	7-11
1767729-6	1991	Urinary urea nitrogen and sodium excretion decreased after IGF-I administration.	Nitrogen	13-21	insulin like growth factor 1	Homo sapiens	59-64
2049167-5	1991	Stored in phosphate buffered saline (PBS) or in a dry nitrogen atmosphere, the nAChR optical sensor showed no loss of activity over the first 3 days, then showed a slow but gradual loss in activity (45% over the next 30 days).	Nitrogen	54-62	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	79-84
1785708-3	1991	It has not been clearly demonstrated that the administration of exogenous insulin with glucose improves nitrogen retention.	Nitrogen	104-112	insulin	Homo sapiens	74-81
2269277-7	1990	Partially or fully de-N-glycosylated erythropoietin derivatives also showed lower in vivo activity but higher in vitro activity than the intact erythropoietin, dependent on the number of sialic acids.	Nitrogen	22-23	erythropoietin	Homo sapiens	37-51
1915160-8	1991	The (GPIIIa)n-TtX complexes are noncovalent size-heterogeneous association products of GPIIIa, tetramers being the smallest form observed.	Nitrogen	12-13	integrin subunit beta 3	Homo sapiens	5-11
1915160-8	1991	The (GPIIIa)n-TtX complexes are noncovalent size-heterogeneous association products of GPIIIa, tetramers being the smallest form observed.	Nitrogen	12-13	integrin subunit beta 3	Homo sapiens	87-93
1675877-0	1991	Nitrogen retention caused by growth hormone in patients undergoing gastrointestinal surgery with epidural analgesia and parenteral nutrition.	Nitrogen	0-8	growth hormone 1	Homo sapiens	29-43
1675877-3	1991	Nitrogen and potassium retention was induced in the growth hormone group compared with the placebo group (cumulative nitrogen balance 4.1 (+/- 1.1) g/m2 in the growth hormone group and -3.1 (+/- 1.8) g/m2 in the placebo group, p less than 0.01; cumulative potassium balance 80.8 (+/- 4.7) mmol/m2 in the growth hormone group and 43.1 (+/- 11.4) mmol/m2 in the placebo group, p less than 0.01).	Nitrogen	0-8	growth hormone 1	Homo sapiens	52-66
1675877-3	1991	Nitrogen and potassium retention was induced in the growth hormone group compared with the placebo group (cumulative nitrogen balance 4.1 (+/- 1.1) g/m2 in the growth hormone group and -3.1 (+/- 1.8) g/m2 in the placebo group, p less than 0.01; cumulative potassium balance 80.8 (+/- 4.7) mmol/m2 in the growth hormone group and 43.1 (+/- 11.4) mmol/m2 in the placebo group, p less than 0.01).	Nitrogen	117-125	growth hormone 1	Homo sapiens	52-66
1656036-5	1991	We conclude that a proper N-glycosylation of helodermin-preferring VIP receptors is required for normal receptor targeting and turnover but not for ligand binding and adenylate cyclase coupling.	Nitrogen	26-27	vasoactive intestinal peptide	Homo sapiens	67-70
1806483-2	1991	The anabolic action of GH involves redistribution of nitrogen from ureogenesis to the extrahepatic anabolic process together with stimulation of amino acid uptake and protein synthesis.	Nitrogen	53-61	growth hormone 1	Homo sapiens	23-25
2030176-0	1991	Effect of long-term bovine somatotropin (sometribove) treatment on nitrogen (protein) distribution in Jersey milk.	Nitrogen	67-75	Weaning weight-maternal milk	Bos taurus	109-113
2030176-12	1991	The differences in nitrogen distribution represent the response during the middle of the injection cycle when milk output was the highest and milk protein the lowest rather than the average response for the injection cycle.	Nitrogen	19-27	Weaning weight-maternal milk	Bos taurus	110-114
2030176-12	1991	The differences in nitrogen distribution represent the response during the middle of the injection cycle when milk output was the highest and milk protein the lowest rather than the average response for the injection cycle.	Nitrogen	19-27	Weaning weight-maternal milk	Bos taurus	142-146
2266133-10	1990	None of Asn-X-Thr/Ser sites on the 107-kDa alpha-mannosidase or on two alpha-mannosidase-invertase fusion proteins that are localized inside the vacuole receives N-linked oligosaccharide, whereas those sites on a carboxypeptidase Y-alpha-mannosidase fusion protein are N-glycosylated.	Nitrogen	0-1	alpha-mannosidase	Saccharomyces cerevisiae S288C	43-60
2266133-10	1990	None of Asn-X-Thr/Ser sites on the 107-kDa alpha-mannosidase or on two alpha-mannosidase-invertase fusion proteins that are localized inside the vacuole receives N-linked oligosaccharide, whereas those sites on a carboxypeptidase Y-alpha-mannosidase fusion protein are N-glycosylated.	Nitrogen	0-1	alpha-mannosidase	Saccharomyces cerevisiae S288C	71-88
2266133-10	1990	None of Asn-X-Thr/Ser sites on the 107-kDa alpha-mannosidase or on two alpha-mannosidase-invertase fusion proteins that are localized inside the vacuole receives N-linked oligosaccharide, whereas those sites on a carboxypeptidase Y-alpha-mannosidase fusion protein are N-glycosylated.	Nitrogen	0-1	alpha-mannosidase	Saccharomyces cerevisiae S288C	71-88
2269277-7	1990	Partially or fully de-N-glycosylated erythropoietin derivatives also showed lower in vivo activity but higher in vitro activity than the intact erythropoietin, dependent on the number of sialic acids.	Nitrogen	22-23	erythropoietin	Homo sapiens	144-158
16348353-1	1990	An ammonium-excreting mutant (SS1) of the rice field nitrogen-fixing cyanobacterium Anabaena siamensis was isolated after ethyl methanesulfonate mutagenesis by selection on 500 muM l-methionine-dl-sulfoximine.	Nitrogen	53-61	major histocompatibility complex, class II, DR beta 1	Homo sapiens	30-33
2229409-2	1990	The role that TNF plays in nitrogen wasting following head injury was studied by measuring TNF in the serum of 21 patients with severe head injury.	Nitrogen	27-35	tumor necrosis factor	Homo sapiens	14-17
2121278-2	1990	D-Galactosamine at a concentration of 4 mM inhibited partially de novo N-glycosylation leading to the formation of alpha 1-antitrypsin lacking one to two and of alpha 1-acid glycoprotein lacking one to five of its carbohydrate side chains.	Nitrogen	71-72	serpin family A member 1	Homo sapiens	115-134
2082620-0	1990	Mutation of conserved N-glycosylation sites around the CD4-binding site of human immunodeficiency virus type 1 GP120 affects viral infectivity.	Nitrogen	22-23	CD4 molecule	Homo sapiens	55-58
2082620-2	1990	To address the possible role of N-glycosylation of HIV-1 gp120 in binding CD4, we mutated different conserved N-glycosylation site Asn-residues in the vicinity of the putative CD4 binding site, as single mutations or in combinations.	Nitrogen	32-33	CD4 molecule	Homo sapiens	74-77
2082620-2	1990	To address the possible role of N-glycosylation of HIV-1 gp120 in binding CD4, we mutated different conserved N-glycosylation site Asn-residues in the vicinity of the putative CD4 binding site, as single mutations or in combinations.	Nitrogen	32-33	CD4 molecule	Homo sapiens	176-179
2080666-3	1990	When cells in the early exponential phase were treated with alpha-mannosidase, or tunicamycin, an inhibitor of N-glycosylation, even higher porosities were obtained.	Nitrogen	111-112	alpha-mannosidase	Saccharomyces cerevisiae S288C	60-77
2273531-10	1990	Growth hormone enhanced the efficiency of administered protein and facilitated nitrogen retention without clinically significant adverse effects in this small patient group.	Nitrogen	79-87	growth hormone 1	Homo sapiens	0-14
1701910-4	1990	Additions of the antagonists N2,O2-dibutyrylguanosine 3":5"-cyclic monophosphate and atropine after 30 min of CCK-8 and carbachol stimulation, respectively, were associated with prompt lowerings of Ca2+i and inhibitions of amylase secretion.	Nitrogen	29-31	cholecystokinin	Homo sapiens	110-113
2270875-7	1990	The flow-rate of the nitrogen carrier gas was 30 ml min-1.	Nitrogen	21-29	CD59 molecule (CD59 blood group)	Homo sapiens	52-57
2235139-0	1990	Whole body nitrogen kinetics and their relationship to growth in short children treated with recombinant human growth hormone.	Nitrogen	11-19	growth hormone 1	Homo sapiens	111-125
16667761-4	1990	The GDH1-null mutant, with a 10- to 15-fold lower total root GDH activity in comparison to the wild type, was found to exhibit a 40 to 50% lower rate of (15)NH(4) (+) assimilation into total reduced nitrogen.	Nitrogen	199-207	glutamate dehydrogenase	Zea mays	4-8
2235139-8	1990	There was a significant (p = 0.03) correlation between the change in height velocity Z score and the degree of nitrogen retention to acute challenge with growth hormone, but this correlation was too weak (r = 0.37) to be of practical value in predicting the treatment growth response in an individual child.	Nitrogen	111-119	growth hormone 1	Homo sapiens	154-168
2144277-1	1990	Rhizobium species produce an inducible acyl carrier protein (ACP), encoded by the nodF gene, that somehow functions in an exchange of cell signals between bacteria and specific plant hosts, leading to nodulation of plant roots and symbiotic nitrogen fixation, as well as a constitutive ACP needed for the synthesis of essential cell lipids.	Nitrogen	241-249	acp	Sinorhizobium meliloti	39-59
2203249-1	1990	In previous studies growth hormone (GH) injections [0.1 mg/kg ideal body wt (IBW) every other day] produced significant increases in plasma insulin-like growth factor I (IGF-I) concentrations and nitrogen retention, which were attenuated when 12 kcal/kg IBW was ingested.	Nitrogen	196-204	growth hormone 1	Homo sapiens	20-34
1697585-6	1990	Sequence analysis revealed that trehalase comprises 578 amino acids, contains at the amino terminus a typical cleavable signal sequence, at the carboxyl terminus a rather hydrophobic region typical of proteins anchored via glycosylphosphatidylinositol, and four potential N-glycosylation sites.	Nitrogen	272-273	trehalase	Oryctolagus cuniculus	32-41
2144277-1	1990	Rhizobium species produce an inducible acyl carrier protein (ACP), encoded by the nodF gene, that somehow functions in an exchange of cell signals between bacteria and specific plant hosts, leading to nodulation of plant roots and symbiotic nitrogen fixation, as well as a constitutive ACP needed for the synthesis of essential cell lipids.	Nitrogen	241-249	acp	Sinorhizobium meliloti	61-64
2144277-1	1990	Rhizobium species produce an inducible acyl carrier protein (ACP), encoded by the nodF gene, that somehow functions in an exchange of cell signals between bacteria and specific plant hosts, leading to nodulation of plant roots and symbiotic nitrogen fixation, as well as a constitutive ACP needed for the synthesis of essential cell lipids.	Nitrogen	241-249	acp	Sinorhizobium meliloti	286-289
2175314-2	1990	Using methanesulfonic acid, hydrolysis of cytochrome c at 115 degrees C for 22 h yielded recoveries equal to or higher than hydrolysis at 115 degrees C for 70 h or at 150 degrees C for 22 h. Triple evacuation of the hydrolysis tube alternated with nitrogen flush gave recovery improvements over single evacuation.	Nitrogen	248-256	cytochrome c, somatic	Homo sapiens	42-54
2374926-3	1990	Residues Ile1 to Tyr3 of hirudin form a parallel beta-strand with Ser214 to Glu217 of thrombin with the nitrogen atom of Ile1 making a hydrogen bond with Ser195 O gamma atom of the catalytic site, but the specificity pocket of thrombin is not involved in the interaction.	Nitrogen	104-112	coagulation factor II, thrombin	Homo sapiens	86-94
1697752-5	1990	Other features deduced from the bovine IGFBP-2 cDNA include: an abundance of leucine in the pre-peptide, an Arg-Gly-Asp sequence, absence of N-linked glycosylation sites, and an imperfect polyadenylation signal as well as an ATTTA motif in the 3" non-coding DNA.	Nitrogen	49-50	insulin like growth factor binding protein 2	Bos taurus	39-46
2377896-2	1990	The power of this technique is demonstrated by the application of four-dimensional carbon-13--nitrogen-15 (13C-15N)--edited nuclear Overhauser effect (NOE) spectroscopy to interleukin-1 beta, a protein of 153 residues.	Nitrogen	94-102	interleukin 1 beta	Homo sapiens	172-190
2380171-3	1990	Hirugen, the synthetic N-acetylated COOH-terminal dodecapeptide (Ac-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3)-Leu) of hirudin was shown in the present study to behave as a pure competitive inhibitor (Ki = 0.54 microM) of human alpha-thrombin-catalyzed release of fibrinopeptide A from human fibrinogen.	Nitrogen	23-24	coagulation factor II, thrombin	Homo sapiens	240-248
2380171-3	1990	Hirugen, the synthetic N-acetylated COOH-terminal dodecapeptide (Ac-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr(SO3)-Leu) of hirudin was shown in the present study to behave as a pure competitive inhibitor (Ki = 0.54 microM) of human alpha-thrombin-catalyzed release of fibrinopeptide A from human fibrinogen.	Nitrogen	23-24	fibrinogen beta chain	Homo sapiens	298-308
2374926-3	1990	Residues Ile1 to Tyr3 of hirudin form a parallel beta-strand with Ser214 to Glu217 of thrombin with the nitrogen atom of Ile1 making a hydrogen bond with Ser195 O gamma atom of the catalytic site, but the specificity pocket of thrombin is not involved in the interaction.	Nitrogen	104-112	coagulation factor II, thrombin	Homo sapiens	227-235
2114255-5	1990	The favorable insulin/glucagon ratio and the control of catecholamine response in early nutritionally supplemented patients are associated with the maintenance of a positive N balance in the days after surgery.	Nitrogen	174-175	insulin	Homo sapiens	14-21
2372541-0	1990	Estimation of disk membrane lateral pressure and molecular area of rhodopsin by the measurement of its orientation at the nitrogen-water interface from an ellipsometric study.	Nitrogen	122-130	rhodopsin	Homo sapiens	67-76
1693949-8	1990	Prokaryotic DBH expression yielded a 65-kilodalton DBH-immunoreactive peptide that differed from eukaryotic adrenal DBH only in N-linked, endoglycosidase F-sensitive glycosylation in the latter.	Nitrogen	128-129	dopamine beta-hydroxylase	Bos taurus	12-15
2112905-5	1990	A positive nitrogen balance of 2 g/d due to growth hormone was probably mediated by insulin.	Nitrogen	11-19	growth hormone 1	Homo sapiens	44-58
2112905-5	1990	A positive nitrogen balance of 2 g/d due to growth hormone was probably mediated by insulin.	Nitrogen	11-19	insulin	Homo sapiens	84-91
2112905-7	1990	The ability of growth hormone to improve nitrogen balance may be particularly important for malnourished patients with chronic obstructive pulmonary disease who, because of their pulmonary insufficiency, are intolerant of excess nutrients.	Nitrogen	41-49	growth hormone 1	Homo sapiens	15-29
2194797-11	1990	Nitrogen-source regulation of the GAP1 permease is believed to occur at two distinct levels, i.e. permease synthesis and permease activity [Grenson (1983) Eur.	Nitrogen	0-8	amino acid permease GAP1	Saccharomyces cerevisiae S288C	34-38
2194797-14	1990	Northern analysis of GAP1-specific transcripts in wild-type and in mutant strains is in agreement with these views and indicates that nitrogen catabolite repression of GAP1 synthesis occurs at the RNA level.	Nitrogen	134-142	amino acid permease GAP1	Saccharomyces cerevisiae S288C	21-25
2194797-14	1990	Northern analysis of GAP1-specific transcripts in wild-type and in mutant strains is in agreement with these views and indicates that nitrogen catabolite repression of GAP1 synthesis occurs at the RNA level.	Nitrogen	134-142	amino acid permease GAP1	Saccharomyces cerevisiae S288C	168-172
2372549-10	1990	Complete assignments are reported for the proton, carbon, and nitrogen backbone resonances of calmodulin, complexed with calcium.	Nitrogen	62-70	calmodulin 1	Homo sapiens	94-104
2195062-1	1990	Prednisone treatment causes protein wasting and adds additional risks to a patient, whereas human growth hormone (hGH) treatment causes positive nitrogen balance.	Nitrogen	145-153	growth hormone 1	Homo sapiens	98-112
2140358-17	1990	The NADPH-dependent CCl4 inhibition was greater under N2 and was totally prevented by CO.	Nitrogen	54-56	C-C motif chemokine ligand 4	Rattus norvegicus	20-24
2372541-4	1990	The orientation of rhodopsin at the nitrogen-water interface was determined by using ellipsometry, which can measure the thickness of the film.	Nitrogen	36-44	rhodopsin	Homo sapiens	19-28
2333977-9	1990	Studies on CCK-7 analogues indicate that N-methylation of the Asp residue is responsible for the observed selectivity for CCK-A receptors.	Nitrogen	41-42	cholecystokinin	Homo sapiens	11-14
2328698-9	1990	These data are consistent with the presence of one potential N-glycosylation site derived from the rPLP-B mRNA sequence.	Nitrogen	61-62	prolactin family 6, subfamily A, member 1	Rattus norvegicus	99-105
2344297-1	1990	We have elucidated the structures of N-linked sugar chains of human apolipoprotein (apo) B-100 (Arch Biochem Biophys 1989; 273:197-205).	Nitrogen	37-38	apolipoprotein B	Homo sapiens	68-94
2131833-6	1990	For reactions in which the SN1 dissociation is unfavorable the forming bond to the incoming nucleophiles in the related SN2 transition state tends to be short and covalent interactions, which favor N-alkylation, play a significant role.	Nitrogen	28-29	solute carrier family 38 member 5	Homo sapiens	120-123
2131833-7	1990	When the SN1 reaction is more facile, the SN2 transition states are "looser" and the covalent interactions correspondingly smaller, leading to an overall shift away from N-alkylation.	Nitrogen	10-11	solute carrier family 38 member 5	Homo sapiens	42-45
2376549-1	1990	Extraction of several nitrogen-containing pesticides from water on solid-phase C18 cartridges was rapid and accurate.	Nitrogen	22-30	Bardet-Biedl syndrome 9	Homo sapiens	79-82
1969925-7	1990	Some of the heterogeneity of PrP is therefore due to differential N-glycosylation.	Nitrogen	66-67	prion protein	Homo sapiens	29-32
1690778-1	1990	N-glycosylation of influenza hemagglutinin abrogates CD4+ cytotoxic T cell recognition of endogenously processed antigen.	Nitrogen	0-1	CD4 molecule	Homo sapiens	53-56
1690778-6	1990	Inasmuch as N-glycosylation of nascent hemagglutinin polypeptides occurs in the lumen of the endoplasmic reticulum, this indicates a route of endogenous processing for hemagglutinin, requiring transport across the endoplasmic reticulum, which has been confirmed by the failure of CD4+ T cells to recognize a recombinant VACC-hemagglutinin virus in which the same single residue change, HA1 63 Asp----Asn has been introduced by site directed mutagenesis.	Nitrogen	12-13	CD4 molecule	Homo sapiens	280-283
1969925-9	1990	The major cause of heterogeneity of PrP is therefore proteolytic cleavage combined with differential glycosylation at the two potential N-glycosylation sites.	Nitrogen	136-137	prion protein	Homo sapiens	36-39
1690778-6	1990	Inasmuch as N-glycosylation of nascent hemagglutinin polypeptides occurs in the lumen of the endoplasmic reticulum, this indicates a route of endogenous processing for hemagglutinin, requiring transport across the endoplasmic reticulum, which has been confirmed by the failure of CD4+ T cells to recognize a recombinant VACC-hemagglutinin virus in which the same single residue change, HA1 63 Asp----Asn has been introduced by site directed mutagenesis.	Nitrogen	12-13	Rho GTPase activating protein 45	Homo sapiens	386-389
2341487-2	1990	Previously, we showed that human tissue plasminogen activator (t-PA) was expressed, N-glycosylated, and secreted by Sf9 cells infected with a recombinant baculovirus (Jarvis DL, Summers MD: Mol Cell Biol 9:214-223, 1989).	Nitrogen	84-85	plasminogen activator, tissue type	Homo sapiens	33-67
2196430-6	1990	Transcription of SME1 was regulated negatively by nitrogen and glucose and positively by MATa/MAT alpha and IME1, another positive regulator gene of meiosis.	Nitrogen	50-58	mRNA splicing protein SME1	Saccharomyces cerevisiae S288C	17-21
2156442-5	1990	Both N2,O2-dibutyryl guanosine 3",5"-cyclic monophosphate (Bt2cGMP) and nitroprusside inhibited the specific binding of 125I-VIP.	Nitrogen	5-7	vasoactive intestinal peptide	Rattus norvegicus	125-128
2156701-8	1990	Although erythropoietin from which N-linked or total sugars were removed also had higher affinity for the receptor, their in vitro activity remained unchanged compared with that of the undigested erythropoietin for unknown reasons.	Nitrogen	35-36	erythropoietin	Homo sapiens	9-23
2312736-3	1990	The GLUT-4 mRNA was reduced in quadriceps muscle (67.5 +/- 8.5%, P = 0.02), but unaltered in adipose tissue (120 +/- 19%, NS), heart (95.7 +/- 6.1%, NS), or diaphragm (75.2 +/- 12.1%, NS) in obese (db/db) mice relative to levels in lean littermates.	Nitrogen	149-151	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	4-10
2156647-14	1990	The high nitrogen intake markedly increased plasma insulin and glucagon concentrations and reduced glycerol, fatty acid and 3-hydroxybutyrate concentrations, independent of any glucose effect.	Nitrogen	9-17	insulin	Homo sapiens	51-58
2156647-16	1990	At this high nitrogen intake, the effects of added glucose appear to be mediated by both insulin and glucagon.	Nitrogen	13-21	insulin	Homo sapiens	89-96
2312736-3	1990	The GLUT-4 mRNA was reduced in quadriceps muscle (67.5 +/- 8.5%, P = 0.02), but unaltered in adipose tissue (120 +/- 19%, NS), heart (95.7 +/- 6.1%, NS), or diaphragm (75.2 +/- 12.1%, NS) in obese (db/db) mice relative to levels in lean littermates.	Nitrogen	149-151	solute carrier family 2 (facilitated glucose transporter), member 4	Mus musculus	4-10
2353926-4	1990	Concerted actions by the triology of factors (AVP, PGE2, Cachectin-TNF) are proposed to instigate a sequence of reactivities that lead to the clinical symptoms of muscle and adipose tissue wasting, together with the negative nitrogen balance characteristic of the cachectic state.	Nitrogen	225-233	tumor necrosis factor	Rattus norvegicus	57-66
2159274-5	1990	Shift of the hydroxy-function to position 3 or 4 as well as N-methylation caused a decrease in AR-affinity.	Nitrogen	60-61	androgen receptor	Homo sapiens	95-97
2313931-2	1990	In cultured hepatocytes treated with CCl4, SAMe-ST and L-Met suppressed the decrease in urea-nitrogen secretion as well as the leakages of GOT and GPT.	Nitrogen	93-101	C-C motif chemokine ligand 4	Rattus norvegicus	37-41
1967418-0	1990	Effect of low-dose bradykinin on glucose metabolism and nitrogen balance in surgical patients.	Nitrogen	56-64	kininogen 1	Homo sapiens	19-29
1967418-5	1990	Patients in the bradykinin group had a significantly improved rate of nitrogen retention (cumulative N balance, -0.014 [SE 0.064] vs -0.175 [0.048] g N/kg) in controls and significantly better nutritional indices.	Nitrogen	70-78	kininogen 1	Homo sapiens	16-26
1967418-6	1990	Manipulation of metabolism in surgical patients by bradykinin may have beneficial effects on nitrogen and protein dynamics, possibly mediated by improved aerobic and anaerobic glycolysis.	Nitrogen	93-101	kininogen 1	Homo sapiens	51-61
2353926-4	1990	Concerted actions by the triology of factors (AVP, PGE2, Cachectin-TNF) are proposed to instigate a sequence of reactivities that lead to the clinical symptoms of muscle and adipose tissue wasting, together with the negative nitrogen balance characteristic of the cachectic state.	Nitrogen	225-233	tumor necrosis factor	Rattus norvegicus	67-70
1969385-5	1990	The mouse beta Mac-1 subunit is highly similar to its human counterpart with an overall sequence identity of 81% and identical positioning of 5 out of 6 potential N-linked glycosylation sites, as well as 56 Cys residues that are organized in repeating motifs characteristic of integrin beta subunits.	Nitrogen	163-164	integrin alpha M	Mus musculus	15-20
1696489-4	1990	The predicted sequence contains three potential N-linked glycosylation sites and shares two region of homology with the low-molecular-weight non-growth-hormone-dependent binding proteins BP-1 and BP-2.	Nitrogen	48-49	BP1	Homo sapiens	187-200
2352577-5	1990	Positive correlations were found between serum FN and nitrogen balance (BN), serum prealbumin (PreA) and transferrin (Tf) in all the patients.	Nitrogen	54-62	fibronectin 1	Homo sapiens	47-49
2109111-6	1990	However, significantly decreased amounts of cytochrome P-450 and reduced meperidine demethylase and pentobarbital hydroxylase activity were present in hepatic microsomes of animals receiving the lipid-poor Vivonex and High Nitrogen Vivonex preparations compared to the other alimentation groups.	Nitrogen	223-231	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	44-60
2139191-4	1990	Administration of hANP resulted in a marked restoration of GFR (29 +/- 2 vs 18 +/- 4 ml/min, P less than or equal to 0.01), diuresis (0.8 +/- 0.1 vs 0.5 +/- 0.1 ml/min, P less than or equal to 0.05), and natriuresis (44 +/- 7 vs 25 +/- 4 mumol/min, P less than or equal to 0.05) on the first postischaemic day, which was mirrored by a reduction in nitrogen retention (Purea: 8 +/- 1 vs 12 +/- 2 mmol/l P less than or equal to 0.05, Pcrea: 137 +/- 20 vs 204 +/- 37 mumol/l).	Nitrogen	348-356	natriuretic peptide A	Homo sapiens	18-22
33971470-9	2021	NO3- mainly originates from soil organic nitrogen (SON), chemical fertilizers (CF), and manure and sewage (M&S).	Nitrogen	41-49	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
33765129-9	2021	Further, consistent with reduced accumulation of free amino acids, ZmPHR1s directly down-regulate ZmAAP2 and ZmLHT1 expression as direct linkers of phosphorus and nitrogen nutrition independent of NIGT1 in the LP maize ear.	Nitrogen	163-171	LHT1	Zea mays	109-115
33815315-4	2021	Mathematic analysis showed that the nitrogen cycle in natural biocrust was driven by dissolved organic N and NO3 -.	Nitrogen	36-44	NBL1, DAN family BMP antagonist	Homo sapiens	109-112
33034380-7	2021	Besides, some CLCs are involved in NO3 - transport and storage function in plants, thus influencing their nitrogen use efficiency.	Nitrogen	106-114	NBL1, DAN family BMP antagonist	Homo sapiens	35-38
33811441-3	2021	Specifically, a two-component gas mixture of water-soluble nitrogen and water-insoluble octafluoropropane as the gas phase are used in a microfluidic bubble generator.	Nitrogen	59-67	gastrin	Mus musculus	30-33
33805223-2	2021	In the present work, statistically robust machine leaning models (QSAR (Quantitative Structure-Activity Relationship) approach) for Human NMT (Hs-NMT) inhibitory has been performed for a dataset of 309 Nitrogen heterocycles screened for NMT inhibitory activity.	Nitrogen	202-210	N-myristoyltransferase 1	Homo sapiens	138-141
33805223-2	2021	In the present work, statistically robust machine leaning models (QSAR (Quantitative Structure-Activity Relationship) approach) for Human NMT (Hs-NMT) inhibitory has been performed for a dataset of 309 Nitrogen heterocycles screened for NMT inhibitory activity.	Nitrogen	202-210	N-myristoyltransferase 1	Homo sapiens	143-149
33805223-2	2021	In the present work, statistically robust machine leaning models (QSAR (Quantitative Structure-Activity Relationship) approach) for Human NMT (Hs-NMT) inhibitory has been performed for a dataset of 309 Nitrogen heterocycles screened for NMT inhibitory activity.	Nitrogen	202-210	N-myristoyltransferase 1	Homo sapiens	146-149
33805223-5	2021	but also provide useful insights into the structural features that sway the Hs-NMT inhibitory activity of Nitrogen heterocycles.	Nitrogen	106-114	N-myristoyltransferase 1	Homo sapiens	79-82
33234475-4	2021	This interaction resulted in diminishing the yellow fluorescence of beta-CD/N@GQDs, and appearance of blue emission peak at 420 nm.	Nitrogen	76-77	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	68-75
33234475-5	2021	Upon addition of DA, the blue emission of beta-CD/N@GQDs was increased after excitation at lambda = 330 nm.	Nitrogen	50-51	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	42-49
15104217-1	2004	OBJECTIVE: To investigate the potential effects of angiogenic process by secretory phospholipase A2 (sPLA2) inhibitor-HyPE (linking N-derivatized phosphatidyl-ethanolamine to hyaluronic acid) on human bone marrow endothelial cell line (HBME-1).	Nitrogen	132-133	phospholipase A2 group X	Homo sapiens	73-99
33232407-10	2021	CONCLUSION: Low-ratio n-6/n-3 PUFA supplementation could decrease significantly the concentration of serum TNF-alpha and IL-6, but not decrease CRP concentration.	Nitrogen	22-23	tumor necrosis factor	Homo sapiens	107-116
33232407-10	2021	CONCLUSION: Low-ratio n-6/n-3 PUFA supplementation could decrease significantly the concentration of serum TNF-alpha and IL-6, but not decrease CRP concentration.	Nitrogen	22-23	interleukin 6	Homo sapiens	121-125
32795780-7	2020	A screening of rat plasma, urine and tissue homogenates revealed 26 new metabolites related to the cytochrome P450 biotransformation pathway, which involves N-oxidation and hydroxylation(s) followed by O-methylation and O-glucuronosylation within phase II of the metabolism.	Nitrogen	157-158	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	99-114
25315061-4	2015	Excellent knockdown (~91%) expressions of Bmh1 in DeltaBmh2 and Bmh2 in DeltaBmh1 resulted in equally more severe multiphenotypic defects than the single deletions, including G2 /M transition, blastospore size, carbon/nitrogen utilization, conidiation, germination and conidial tolerances to high osmolarity, oxidation, cell wall stress, high temperature and UV-B irradiation.	Nitrogen	218-226	14-3-3 family protein BMH1	Saccharomyces cerevisiae S288C	42-46
15104217-1	2004	OBJECTIVE: To investigate the potential effects of angiogenic process by secretory phospholipase A2 (sPLA2) inhibitor-HyPE (linking N-derivatized phosphatidyl-ethanolamine to hyaluronic acid) on human bone marrow endothelial cell line (HBME-1).	Nitrogen	132-133	phospholipase A2 group X	Homo sapiens	101-106
15104217-1	2004	OBJECTIVE: To investigate the potential effects of angiogenic process by secretory phospholipase A2 (sPLA2) inhibitor-HyPE (linking N-derivatized phosphatidyl-ethanolamine to hyaluronic acid) on human bone marrow endothelial cell line (HBME-1).	Nitrogen	132-133	FIC domain protein adenylyltransferase	Homo sapiens	118-122
34973200-1	2022	In order to effectively remove refractory bisphenol A (BPA) from water, a novel nitrogen doped organic porous functional azo linked polymer (ALP-p) was designed and prepared according to the physicochemical characteristics of propane linked to two phenol hydroxyl groups.	Nitrogen	80-88	alkaline phosphatase, placental	Homo sapiens	141-146
10652043-6	2000	RESULTS: During the treatment with rhIGF-1, serum IGF-1 increased by about 100% (P = 0.03), and nitrogen balance became strongly positive (+2.0 g/day, P = 0.015 vs. baseline).	Nitrogen	96-104	insulin like growth factor 1	Homo sapiens	37-42
8070361-2	1994	The rat PACE4 sequence has the Asp-His-Ser catalytic site triad, an Arg-Gly-Asp potential integrin binding site, and three potential sites for N-linked glycosylation.	Nitrogen	143-144	proprotein convertase subtilisin/kexin type 6	Rattus norvegicus	8-13
34910946-9	2022	The trips in Beijing have approximately 14%, 57%, 14%, and 21% lower emissions of carbon dioxide (CO2), carbon monoxide (CO), nitrogen oxides (NOx), and particle number (PN), respectively.	Nitrogen	126-134	U6 snRNA biogenesis phosphodiesterase 1	Homo sapiens	170-172
34973379-3	2022	Melatonin and SA applied jointly or alone enhanced nitrogen metabolism by triggering the activities of glutamate synthase, glutamine synthetase, and nitrite reductases and nitrate.	Nitrogen	51-59	glutamate-ammonia ligase	Homo sapiens	123-143
34799437-5	2022	Results Urat1-Uox DKO mice had uricosuric effects and elevated levels of plasma creatinine (Cr) and blood urea nitrogen (BUN) as renal injury markers, and decreased Cr clearance (CLCr) observed in a forced swimming test.	Nitrogen	111-119	urate oxidase	Mus musculus	14-17
34848359-11	2022	The results showed that DWPE could decline the concentration of ammonia and increase the expressions of carbonic anhydrase 2 (CA2) and carbamoylphosphate synthetase (CPS1) in nitrogen metabolism.	Nitrogen	175-183	carbonic anhydrase 2	Rattus norvegicus	104-124
34848359-11	2022	The results showed that DWPE could decline the concentration of ammonia and increase the expressions of carbonic anhydrase 2 (CA2) and carbamoylphosphate synthetase (CPS1) in nitrogen metabolism.	Nitrogen	175-183	carbonic anhydrase 2	Rattus norvegicus	126-129
34802756-7	2022	The spectroscopic analyses based on FTIR, Raman, and XPS measurements suggest electrostatic, n-pi, pi-pi, cation-pi interactions, dipole-dipole hydrogen, and Yoshida hydrogen linkages as major interactive pathways for the adsorption of organic dyes by the CGA.	Nitrogen	93-94	chromogranin A	Homo sapiens	256-259
34492279-9	2022	Increased total n-3 PUFA (DHA, EPA and ALA) was significantly associated with lower IL-10 (beta = -0.667; p = 0.007) and lower total Th2 (IL-4, IL-10 and IL-13) (beta = -0.715; p = 0.036).	Nitrogen	16-17	interleukin 4	Homo sapiens	138-142
34492279-9	2022	Increased total n-3 PUFA (DHA, EPA and ALA) was significantly associated with lower IL-10 (beta = -0.667; p = 0.007) and lower total Th2 (IL-4, IL-10 and IL-13) (beta = -0.715; p = 0.036).	Nitrogen	16-17	interleukin 13	Homo sapiens	154-159
34848225-8	2022	The XPS and FT-IR analysis results indicated that the sulfur-, nitrogen- and oxygen-containing groups in the keratin-PAA hydrogel were the main binding sites for Pb(II).	Nitrogen	63-71	submaxillary gland androgen regulated protein 3B	Homo sapiens	162-168
34904438-3	2022	The reaction also underscored an intermolecular nitrogen-atom transfer process from TMS-azide leading to final products, where any intermediary azidothiazolidinone was absent.	Nitrogen	48-56	PYD and CARD domain containing	Homo sapiens	84-87
34736661-0	2022	Hierarchical nickel hydroxide nanosheets grown on hollow nitrogen doped carbon nanoboxes as a high-performance surface substrate for alpha-fetoprotein cancer biomarkers electrochemical aptasensing.	Nitrogen	57-65	alpha fetoprotein	Homo sapiens	133-150
34767281-0	2022	Developing efficient small molecule acceptors with sp2-hybridized nitrogen at different positions by density functional theory calculations, molecular dynamics simulations and machine learning.	Nitrogen	66-74	Sp2 transcription factor	Homo sapiens	51-54
34767281-3	2022	Herein, the effect of sp 2 -hybridized nitrogen substitution at the inner or the outmost position of central core, side chain, and terminal group of small molecule acceptors is investigated using multiscale computational modelling.	Nitrogen	39-47	Sp2 transcription factor	Homo sapiens	22-26
34936333-0	2022	Reactive Nitrogen Species Generated by Gas-Liquid Dielectric Barrier Discharge for Efficient Degradation of Perfluorooctanoic Acid from Water.	Nitrogen	9-17	PAXIP1 associated glutamate rich protein 1	Homo sapiens	39-42
34666020-0	2022	Cytotoxic activity and influence on acetylcholinesterase of series dinuclear platinum(II) complexes with aromatic nitrogen-containing heterocyclic bridging ligands: Insights in the mechanisms of action.	Nitrogen	114-122	acetylcholinesterase (Cartwright blood group)	Homo sapiens	36-56
34914357-1	2022	Electrocatalytic nitrate (NO3-) reduction to N2 via atomic hydrogen (H*) is a promising approach for advanced water treatment.	Nitrogen	45-47	NBL1, DAN family BMP antagonist	Homo sapiens	26-29
34914357-6	2022	In addition, in situ differential electrochemical mass spectrometry (DEMS) indicated that ultrafast *NO2- to *NO reduction and highly selective *NO to *N2O or *N transformation played crucial roles during the NO3- reduction process.	Nitrogen	160-161	NBL1, DAN family BMP antagonist	Homo sapiens	209-212
34785327-2	2022	Approximately 83.66% total nitrogen removal efficiency (TNRE) could be achieved by the sulfurized Anammox encrusted by S0/Sn2- at a high loading rate (2.6 kg-N/(m3 d)) via resisting high concentration of free ammonia (FA) (22.35 mg/L), mainly through S2O32-, S0/Sn2- -driven partial denitrification-Anammox (PDN-Anammox) process.	Nitrogen	27-35	solute carrier family 38 member 5	Homo sapiens	122-125
34798465-4	2022	The present study demonstrated that PIF3 and PIF5 can slightly repress anthocyanin accumulation under NaCl, low nitrogen (-N), or 6-BA treatments; in contrast, PIF4 can significantly repress anthocyanin accumulation.	Nitrogen	112-120	phytochrome interacting factor 3	Arabidopsis thaliana	36-40
34923327-4	2022	The isotopic measurements provide information about potential nitrogen sources contributing NO3- to the groundwater.	Nitrogen	62-70	NBL1, DAN family BMP antagonist	Homo sapiens	92-95
34923327-5	2022	Based on isotope analysis, the sources of NO3- in the groundwater of this region are likely to be from (a) septic sewage (b) organic nitrogen (animal and livestock excreta) (c) sewage (domestic & chemical fertilizers).	Nitrogen	133-141	NBL1, DAN family BMP antagonist	Homo sapiens	42-45
34619589-1	2022	Membrane photosynthetic microbial fuel cell (MPMFC) utilizes O2, NO3- and NO2- as cathodic electron acceptors, enabling simultaneous treatment of nitrogen, CO2 and organic carbon in the cathode compartment.	Nitrogen	146-154	NBL1, DAN family BMP antagonist	Homo sapiens	65-68
34853076-3	2022	Native C5a contains a large N-linked glycosylation site at Asn64, which accounts for up to 25% of its m.w.	Nitrogen	28-29	complement C5a receptor 1	Homo sapiens	7-10
34972198-5	2021	Loss of TSC1 and TSC2, that are negative regulators of TOR complex 1 (TORC1) in mammalian cells, resulted in altered nitrogen source-dependent growth of T. atroviride, reduced mycoparasitic overgrowth and, in the case of Deltatsc1, a diminished production of numerous secondary metabolites.	Nitrogen	117-125	TSC complex subunit 1	Homo sapiens	8-12
34814021-8	2022	In case of NaOH as the electrolyte, the single-pass nitrate removal efficiency, selectivity to nitrogen formation and nitrate removal rate was 90.66%, 96.40% and 1.47 x 10-3 mmol min-1 cm-2, respectively.	Nitrogen	95-103	CD59 molecule (CD59 blood group)	Homo sapiens	179-189
34913689-3	2021	Here, CoSe2/nitrogen-doped carbon-skeleton hybrid microcubes with a TiO2 layer (denoted as TNC-CoSe2) are favorably prepared via a facile template-engaged strategy, in which a TiO2-coated Prussian blue analogue of Co3(Co(CN)6)2 is used as a new precursor accompanied with a selenization procedure.	Nitrogen	12-20	tenascin C L homeolog	Xenopus laevis	91-94
34972374-10	2021	Some additional features in the (18,m) spectra at high N2 loads indicate a mu1,tilt tilted end-on adsorption motif.	Nitrogen	55-57	glutathione S-transferase mu 1	Homo sapiens	75-78
34963193-8	2022	Based on gene set enrichment analysis, hyper-methylation of CASP1, CFH, and TTLL7 were found enriched in tumor-related KEGG terms, such as "RNA degradation", "apyruvate metabolism", and "nitrogen metabolism".	Nitrogen	187-195	caspase 1	Homo sapiens	60-65
34974023-3	2022	Ice cores contain records of nitrogen species of nitrate (NO3-) and ammonium (NH4+), hence provide valuable long-term data to study past variations of atmospheric nitrogen deposition.	Nitrogen	29-37	NBL1, DAN family BMP antagonist	Homo sapiens	58-61
34974023-5	2022	The concentration peaks of NH4+ and NO3- coincide with those of Ca2+ (a dust tracer), indicating that variation of nitrogen species in the ZK ice core is largely driven by dust activities.	Nitrogen	115-123	NBL1, DAN family BMP antagonist	Homo sapiens	36-39
34774484-4	2021	The current study explored the significance of N-glycosylation of Trop2 by substituting specific N-glycan addition sites by site-directed mutagenesis.	Nitrogen	47-48	tumor associated calcium signal transducer 2	Homo sapiens	66-71
34936716-4	2022	Our data showed that increased expression of NDUFV1 improves kidney function as evidenced by the decreases in blood urea nitrogen and serum creatinine in UUO mice.	Nitrogen	121-129	NADH:ubiquinone oxidoreductase core subunit V1	Mus musculus	45-51
34752419-8	2021	Consistently, N-glycosylated proteins and N-glycan biosynthesis genes were differentially expressed during metastatic BC progression, with reduced expression of EpCAM and mannose-trimming enzymes and elevated N-glycan branching and sialylation enzymes in BC metastases versus PT.	Nitrogen	14-15	epithelial cell adhesion molecule	Homo sapiens	161-166
34774484-0	2021	N-glycosylation status of Trop2 impacts its surface density, interaction with claudin-7 and exosomal release.	Nitrogen	0-1	tumor associated calcium signal transducer 2	Homo sapiens	26-31
34774484-1	2021	Trophoblast antigen 2 (Trop2) is a type I transmembrane protein post-translationally modified by N-linked glycosylation.	Nitrogen	97-98	tumor associated calcium signal transducer 2	Homo sapiens	0-21
34774484-1	2021	Trophoblast antigen 2 (Trop2) is a type I transmembrane protein post-translationally modified by N-linked glycosylation.	Nitrogen	97-98	tumor associated calcium signal transducer 2	Homo sapiens	23-28
34908451-0	2021	Application of Recombinant Human scFv Antibody as a Powerful Tool to Monitor Nitrogen Fixing Biofertilizer in Rice and Legume.	Nitrogen	77-85	immunglobulin heavy chain variable region	Homo sapiens	33-37
34908205-5	2022	Whereas eCO2 showed no individual effect, eT had distinct effects which were modulated by season, with a negative effect of eT on soil organic N process rates in spring, neutral effects in summer, and positive effects in fall.	Nitrogen	143-144	major facilitator superfamily domain containing 11	Homo sapiens	42-44
34870671-1	2021	Nitrogen speciation, i.e. distinguishing nitrate (NO3-) and ammonium (NH4+), is commonly undertaken in soil studies, but has not been conducted extensively for lichens.	Nitrogen	0-8	NBL1, DAN family BMP antagonist	Homo sapiens	50-53
34870671-3	2021	Albeit nitrogen being an essential lichen nutrient, nitrogen compound (i.e. NO3- and NH4+) concentrations in the atmosphere can have deleterious effects on lichens.	Nitrogen	52-60	NBL1, DAN family BMP antagonist	Homo sapiens	76-79
34908205-5	2022	Whereas eCO2 showed no individual effect, eT had distinct effects which were modulated by season, with a negative effect of eT on soil organic N process rates in spring, neutral effects in summer, and positive effects in fall.	Nitrogen	143-144	major facilitator superfamily domain containing 11	Homo sapiens	124-126
34695755-7	2021	Although Gid10 shares many structural features with the Gid4 protein from yeast and humans, the current structure explains the unique structural difference for the preference of bulky hydrophobic residue at the second position of Pro/N-degron.	Nitrogen	234-235	glucose-induced degradation complex subunit VID24	Saccharomyces cerevisiae S288C	56-60
34802226-1	2021	In this work, a novel electrochemical immunosensor based on nitrogen doped graphene quantum dot (N-GQD) and single-walled carbon nanohorns (SWCNHs) was developed for the detection of alpha-fetoprotein (AFP), a cancer biomarker.	Nitrogen	60-68	alpha fetoprotein	Homo sapiens	183-200
34802226-1	2021	In this work, a novel electrochemical immunosensor based on nitrogen doped graphene quantum dot (N-GQD) and single-walled carbon nanohorns (SWCNHs) was developed for the detection of alpha-fetoprotein (AFP), a cancer biomarker.	Nitrogen	60-68	alpha fetoprotein	Homo sapiens	202-205
34946583-1	2021	sp2-Iminosugar glycolipids (sp2-IGLs) represent a consolidated family of glycoconjugate mimetics encompassing a monosaccharide-like glycone moiety with a pseudoamide-type nitrogen replacing the endocyclic oxygen atom of carbohydrates and an axially-oriented lipid chain anchored at the pseudoanomeric position.	Nitrogen	171-179	Sp2 transcription factor	Homo sapiens	0-3
34946583-1	2021	sp2-Iminosugar glycolipids (sp2-IGLs) represent a consolidated family of glycoconjugate mimetics encompassing a monosaccharide-like glycone moiety with a pseudoamide-type nitrogen replacing the endocyclic oxygen atom of carbohydrates and an axially-oriented lipid chain anchored at the pseudoanomeric position.	Nitrogen	171-179	Sp2 transcription factor	Homo sapiens	28-31
34946583-3	2021	The exacerbated anomeric effect associated to the putative sp2-hybridized N-atom imparts chemical and enzymatic stability to sp2-IGLs and warrants total alpha-anomeric stereoselectivity in the key glycoconjugation step.	Nitrogen	74-75	Sp2 transcription factor	Homo sapiens	59-62
34946583-3	2021	The exacerbated anomeric effect associated to the putative sp2-hybridized N-atom imparts chemical and enzymatic stability to sp2-IGLs and warrants total alpha-anomeric stereoselectivity in the key glycoconjugation step.	Nitrogen	74-75	Sp2 transcription factor	Homo sapiens	125-128
34946583-6	2021	Structure-activity relationship studies in three different scenarios, namely cancer, Leishmaniasis and inflammation, convey that the therapeutic potential of the sp2-IGLs is highly dependent, not only on the length of the lipid chain (linear aliphatic C12 vs. C8), but also on the nature of the glycosidic atom (nitrogen vs. sulfur vs. selenium).	Nitrogen	312-320	Sp2 transcription factor	Homo sapiens	162-165
34536740-4	2021	Reducing N application from historical to model optimized agronomic rates sharply lowered corn NO3- leaching from 75.3 to 24.9 kt N per year.	Nitrogen	9-10	NBL1, DAN family BMP antagonist	Homo sapiens	95-98
34536740-4	2021	Reducing N application from historical to model optimized agronomic rates sharply lowered corn NO3- leaching from 75.3 to 24.9 kt N per year.	Nitrogen	130-131	NBL1, DAN family BMP antagonist	Homo sapiens	95-98
34904350-3	2022	Surprisingly, the derived helicate tetramines possessed amino groups with a planar structure and sp 2 -hybridized nitrogen that are never reported, arousing the change between AIE effect and ACQ phenomenon through photoinduced electron transfer (PET).	Nitrogen	114-122	Sp2 transcription factor	Homo sapiens	97-101
34898426-4	2021	We have established the functional coupling between enzymatic activity and protein morphological states of glutamine synthetase (GS), an old multi-subunit enzyme essential for cellular nitrogen metabolism.	Nitrogen	185-193	glutamate-ammonia ligase	Homo sapiens	107-127
34898426-4	2021	We have established the functional coupling between enzymatic activity and protein morphological states of glutamine synthetase (GS), an old multi-subunit enzyme essential for cellular nitrogen metabolism.	Nitrogen	185-193	glutamate-ammonia ligase	Homo sapiens	129-131
34966404-8	2021	An increase was observed in some key enzymatic activities and transcription involved in nitrogen metabolism, such as that of nitrate reductase, nitrite reductase, glutamate synthase, and glutamine synthetase, in melatonin-treated, drought-stressed maize.	Nitrogen	88-96	ferredoxin--nitrite reductase, chloroplastic	Zea mays	144-161
34899874-8	2021	Keywords were classified into five clusters, indicating the five main research focuses on CED studies: hydrological cycle, effects of climate change, carbon and water balance, productivity, and carbon-nitrogen-phosphorous coupling cycles.	Nitrogen	201-209	intraflagellar transport 122	Homo sapiens	90-93
34948109-5	2021	After orthotopic delivery of PD-L1 gene into the kidneys, cisplatin-exposed mice displayed lower levels of both serum urea nitrogen and creatinine upon PD-L1 expression.	Nitrogen	123-131	CD274 antigen	Mus musculus	29-34
34948109-5	2021	After orthotopic delivery of PD-L1 gene into the kidneys, cisplatin-exposed mice displayed lower levels of both serum urea nitrogen and creatinine upon PD-L1 expression.	Nitrogen	123-131	CD274 antigen	Mus musculus	152-157
34866298-9	2022	Stover return with application of N 250 kg ha-1 significantly increased the growth attribute and maize yield in subtropical region compared with traditional planting.	Nitrogen	34-35	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	43-47
34943041-3	2021	In this paper, we show that F. hepatica-infected mice upregulate HO-1 on peritoneal antigen-presenting cells (APC), which produce decreased levels of both reactive oxygen and nitrogen species (ROS/RNS).	Nitrogen	175-183	heme oxygenase 1	Mus musculus	65-69
34839261-7	2021	NF-kappaB/STT3A-regulated N-glycosylation was investigated by gene knockdown, chromatin immunoprecipitation, and promoter assay.	Nitrogen	26-27	nuclear factor kappa B subunit 1	Homo sapiens	0-9
34024253-0	2021	Parathyroid hormone-related protein inhibits nitrogen-containing bisphosphonate-induced apoptosis of human periodontal ligament fibroblasts by activating MKP1 phosphatase.	Nitrogen	45-53	dual specificity phosphatase 1	Homo sapiens	154-158
34024253-4	2021	Therefore, it is speculated that PTHrP can inhibit the apoptosis of HPdLFs caused by nitrogen-containing BP via regulating the expression levels of MKP1.	Nitrogen	85-93	dual specificity phosphatase 1	Homo sapiens	148-152
34319422-1	2021	The yeast prions (infectious proteins) (URE3) and (PSI+) are essentially non-functional (or even toxic) amyloid forms of Ure2p and Sup35p, whose normal function is in nitrogen catabolite repression and translation termination, respectively.	Nitrogen	167-175	glutathione peroxidase	Saccharomyces cerevisiae S288C	121-126
34024253-10	2021	Altogether, PTHrP can inhibit nitrogen-containing BP-induced apoptosis of HPdLFs by activating MKP1 phosphatase.	Nitrogen	30-38	dual specificity phosphatase 1	Homo sapiens	95-99
34664138-11	2021	We suggest that expression of TRPV3 by epithelia may have implications not just for Ca2+ signalling, but also for nitrogen metabolism.	Nitrogen	114-122	transient receptor potential cation channel subfamily V member 3	Homo sapiens	30-35
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	61-69	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	61-69	NBL1, DAN family BMP antagonist	Homo sapiens	366-369
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	106-114	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	106-114	NBL1, DAN family BMP antagonist	Homo sapiens	366-369
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	159-167	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	159-167	NBL1, DAN family BMP antagonist	Homo sapiens	366-369
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	228-236	NBL1, DAN family BMP antagonist	Homo sapiens	23-26
34273081-4	2021	Results indicated that NO3--N was the main form of inorganic nitrogen in this area, and the average total nitrogen content was 10.23 mg L-1, which showed that nitrogen pollution was highly serious; the transformation process of nitrogen in this study area was mainly nitrification; The results of Bayesian model showed that manure and sewage contributed to the most NO3- (64.39%) in the dry season, followed by soil nitrogen, which was 26.35%.	Nitrogen	228-236	NBL1, DAN family BMP antagonist	Homo sapiens	366-369
33243025-1	2021	A series of C4-substituted tertiary nitrogen-bearing 2"-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor.	Nitrogen	36-44	acetylcholinesterase (Cartwright blood group)	Homo sapiens	134-154
34116494-6	2021	Furthermore, the oxygen-containing groups of wheat proteins, the nitrogen-containing groups of albumins and globulins, and the sulfur-containing groups of gliadins and glutenins were found to offer coordination sites for Pb(II).	Nitrogen	65-73	submaxillary gland androgen regulated protein 3B	Homo sapiens	221-227
34520881-2	2021	This study aimed to compare the effectiveness and sensitivity of in-office dental bleaching with one versus two applications of 6% hydrogen peroxide (HP) gel with nitrogen titanium dioxide (TiO2) nanoparticles activated by LED/Laser lamp in a single-session.	Nitrogen	163-171	small integral membrane protein 10 like 2A	Homo sapiens	223-226
34590721-6	2021	In contrast, phyB2 reduced N accumulation, quantum efficiency of photosystem II (Fv/Fm) and the concentration of pigments, while it increased MDA.	Nitrogen	27-28	phytochrome B2	Solanum lycopersicum	13-18
34885789-1	2021	Leghemoglobin (Lb) is an oxygen-binding plant hemoglobin of legume nodules, which participates in the symbiotic nitrogen fixation process.	Nitrogen	112-120	leghemoglobin A	Glycine max	0-13
34784468-1	2021	Hindered rotation about an sp2 C-N bond is known to occur in arginine (Arg), asparagine (Asn), and glutamine (Gln) side chains of proteins.	Nitrogen	33-34	Sp2 transcription factor	Homo sapiens	27-30
34517598-5	2021	The concentration of cofactors (NADH, NAD+) and substrates (fructose, sorbitol) for SDH determination at a strip was optimized via internally-calibrated amperometric assays at a chitosan/nitrogen-doped carbon nanotube electrode.	Nitrogen	187-195	sorbitol dehydrogenase	Homo sapiens	84-87
34608685-3	2021	The reaction of 1 with one equiv of PhCOMe, Ar 1 CHO (Ar 1 = 2,6-Me 2 C 6 H 3 ), W(CO) 6 , and PhCH=NPh provided oxalutetacyclopentenes, metallacyclic lutetoxycarbene, and azalutetacyclopentene via 1,2-insertion of C=O, C O, or C=N bonds into Lu-C sp2 bond, respectively.	Nitrogen	230-231	regulator of calcineurin 2	Homo sapiens	246-251
34831023-2	2021	FAM72A interacts with the uracil-DNA glycosylase UNG2 to prevent mutagenesis by eliminating uracil from DNA molecules through cleaving the N-glycosylic bond and initiating the base excision repair pathway, thus maintaining genome integrity.	Nitrogen	139-140	uracil DNA glycosylase	Homo sapiens	49-53
34864344-3	2021	In the present study, a series of bioretention columns were established to monitor their fate performance for inorganic N (NH4+and NO3-) by using different configurations and by dosing with simulated stormwater events.	Nitrogen	120-121	NBL1, DAN family BMP antagonist	Homo sapiens	131-134
34797410-6	2021	For 2019, the deficit for N was -104.8 kg ha1, for P -8.7 kg ha-1, and for K -134.5 kg ha-1, making Albania have the largest deficit of soil nutrients compared to EU and OECD countries.	Nitrogen	26-27	Rho GTPase activating protein 45	Homo sapiens	42-45
34788664-3	2022	Feammox can produce N2, NO2- or NO3- through the reduction of Fe(III) and oxidation of ammonium, which is a potential process to nitrogen loss from aquatic ecosystems and terrestrial ecosystems.	Nitrogen	129-137	NBL1, DAN family BMP antagonist	Homo sapiens	32-35
34988394-0	2021	Amyloid-beta-copper interaction studied by simultaneous nitrogen K and copper L2,3 -edge soft X-ray absorption spectroscopy.	Nitrogen	56-64	amyloid beta precursor protein	Homo sapiens	0-12
34130174-3	2021	EXPERIMENTS: The graphene hydrogel-based nitrogen-arbon materials (GH N-C) were fabricated by first obtaining a gel through hydrothermal treatment using graphene oxide (GO) as precursor, and then calcined in an ammonia atmosphere at different temperatures to form N-doped graphitized materials with divers nitrogen configuration.	Nitrogen	41-49	growth hormone 1	Homo sapiens	67-71
34832966-12	2021	Bcl-2 levels were reduced only in SK-N-FI cells after treatment with cisplatin.	Nitrogen	36-39	BCL2 apoptosis regulator	Homo sapiens	0-5
34783117-3	2022	The synthesized nitrogen-based novel heterocyclic compounds were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes.	Nitrogen	16-24	acetylcholinesterase (Cartwright blood group)	Homo sapiens	152-172
34783117-3	2022	The synthesized nitrogen-based novel heterocyclic compounds were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes.	Nitrogen	16-24	acetylcholinesterase (Cartwright blood group)	Homo sapiens	174-178
34783117-4	2022	The synthesized nitrogen-based novel heterocyclic compounds showed IC50 values in the range of 2.69-7.01 against hCA I, 2.40-4.59 against hCA II, 0.81-1.32 microM against AChE, and 20.83-1.70 microM against BChE enzymes.	Nitrogen	16-24	acetylcholinesterase (Cartwright blood group)	Homo sapiens	171-175
34783117-5	2022	On the contrary, nitrogen-based novel heterocyclic compounds demonstrated Ki values between 2.93 +- 0.59-8.61 +- 1.39 against hCA I, 2.05 +- 0.62-4.97 +- 0.95 against hCA II, 0.34 +- 0.02-0.92 +- 0.17 nM against AChE, and 0.50 +- 0.04-1.20 +- 0.16 microM against BChE enzymes.	Nitrogen	17-25	acetylcholinesterase (Cartwright blood group)	Homo sapiens	212-216
34873473-2	2021	In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (MET) and epidermal growth factor receptor (EGFR).	Nitrogen	110-111	MET proto-oncogene, receptor tyrosine kinase	Homo sapiens	255-267
34873473-2	2021	In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (MET) and epidermal growth factor receptor (EGFR).	Nitrogen	110-111	epidermal growth factor receptor	Homo sapiens	278-310
34873473-2	2021	In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (MET) and epidermal growth factor receptor (EGFR).	Nitrogen	110-111	epidermal growth factor receptor	Homo sapiens	312-316
34747459-9	2021	When 2B11.3 was injected, CCR2-/- and CCR5-/-, but not CX3CR1-/-, mice exhibited reduced endocapillary hypercellularity, attenuated glomerular macrophage infiltration, and improved serum blood urea nitrogen (BUN) levels.	Nitrogen	198-206	chemokine (C-C motif) receptor 5	Mus musculus	38-42
34586812-1	2021	Detonation energy of novel cyclo-N5--based nitrogen-rich energetic salts is expected to exceed 3 times the equivalent of TNT.	Nitrogen	43-51	chromosome 16 open reading frame 82	Homo sapiens	121-124
34743203-10	2022	Based on point mutation of glycosylation sites, we confirmed the N-glycosylation of PTGDS in Asn51 and Asn78 and found that abnormal glycosylation of PTGDS resulted in its nuclear translocation, prolonged half-life, and enhanced cell proliferation.	Nitrogen	65-66	prostaglandin D2 synthase	Homo sapiens	84-89
34618046-9	2021	Taken together, our results illustrate a mechanism by which CML38 interacts with PEPR2 to integrate LN and BR signals for coordinating root development to prevent quick depletion of N resources in Arabidopsis.	Nitrogen	182-183	PEP1 receptor 2	Arabidopsis thaliana	81-86
34726182-1	2021	Glutamine synthetase (GS) is a decameric enzyme that plays a key role in nitrogen metabolism.	Nitrogen	73-81	glutamate-ammonia ligase	Homo sapiens	0-20
34726182-1	2021	Glutamine synthetase (GS) is a decameric enzyme that plays a key role in nitrogen metabolism.	Nitrogen	73-81	glutamate-ammonia ligase	Homo sapiens	22-24
34292591-4	2021	Using primary cultured rat hepatocytes, we first confirmed the mitochondrial expression of hAQP8 and then, using unlabeled or 15 N-labeled ammonia, we demonstrated that the urea synthesis was significantly enhanced in hAQP8-transduced hepatocytes.	Nitrogen	129-130	aquaporin 8	Homo sapiens	218-223
34563998-1	2021	Twenty-one AD-1 derivatives were designed and synthesized by introducing various nitrogen-containing heterocycles into C-2 and C-3 positions.	Nitrogen	81-89	amyloid beta precursor protein	Homo sapiens	11-15
34115303-3	2021	NO3-/Cl- molar ratios and nitrate dual isotopes indicated that NO3- was mainly from chemical fertilizer (CF) in zones 1 (57.0%) and 2 (43.1%) according to a Bayesian mixing model (SIAR) and mixed sources of CF, nitrification of soil organic nitrogen (SON), and manure and sewage (M&S) in zone 3 (92.8%), during the high-flow season.	Nitrogen	241-249	NBL1, DAN family BMP antagonist	Homo sapiens	63-66
34656860-5	2021	We demonstrate that NPF6.2/NRT1.4 is a plasma membrane nitrate transporter phosphorylated at threonine-98 by the CIPK23 protein kinase that is a regulatory hub for nitrogen and potassium nutrition.	Nitrogen	164-172	Major facilitator superfamily protein	Arabidopsis thaliana	20-26
34674311-5	2021	The four-transmembrane protein TMEM43 with the p.S358L variant (TMEM43S358L ) was found to be modified by N-linked glycosylation in both KI rat cardiomyocytes and patient-specific iPSC-derived cardiomyocytes.	Nitrogen	106-107	transmembrane protein 43	Rattus norvegicus	31-37
34539828-5	2021	They also inhibit cyclooxygenase 2, thereby decreasing the secretion of prostaglandin E2 and nitrogen oxide, and reducing the risk of miscarriage in the first trimester of pregnancy.	Nitrogen	93-101	prostaglandin-endoperoxide synthase 2	Homo sapiens	18-34
33637588-11	2021	Conclusion: NOTA-conjugated, cyclic peptides derived from the known ACE2 inhibitor DX600 retain their activity when N-conjugated for 68Ga chelation.	Nitrogen	116-117	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	Mus musculus	68-72
34620437-8	2021	gat1_2.1 exhibited reduced growth as compared with wild-type seedlings on media with glutamine as sole nitrogen source.	Nitrogen	103-111	Class I glutamine amidotransferase-like superfamily protein	Arabidopsis thaliana	0-8
34620437-10	2021	GAT1_2.1 may act as a glutaminase, in concert with Glutamate Dehydrogenase 2, to hydrolyze glutamine and channel 2-oxoglutarate to the TCA cycle under high nitrogen conditions.	Nitrogen	156-164	Class I glutamine amidotransferase-like superfamily protein	Arabidopsis thaliana	0-8
34737629-1	2021	Background: We aimed to evaluate the prognostic ability of blood urea nitrogen (BUN) to serum albumin ratio (BAR) to predict in-hospital mortality in patients with lung cancer in the intensive care unit (ICU).	Nitrogen	70-78	albumin	Homo sapiens	94-101
34718979-5	2022	Moreover, the addition of human manure increased the proportions of Nr footprint by 6.6% (CHF1) and 2.9% (CHF2) in comparison with CF treatment.	Nitrogen	68-70	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	106-110
34718979-6	2022	However, although CHF2 treatment significantly increased the values of GNrEs and reactive gaseous nitrogen intensity (GNrI) by 8.4% and 12.5%, respectively, in relation to those in CF treatment, it still increased farmers" income by 16,404 CNY ha-1.	Nitrogen	98-106	hes related family bHLH transcription factor with YRPW motif 1	Homo sapiens	18-22
34727639-4	2022	The concentrations of serum triglyceride, total cholesterol and interleukin 6 were linearly increased (p<0.05) with increasing of dietary n-6:n-3 PUFA ratio, while that of high-density lipoprotein cholesterol tended to decrease (p = 0.062), and high-density lipoprotein cholesterol:low-density lipoprotein cholesterol ratio and leptin concentration was linearly decreased (p<0.05).	Nitrogen	138-140	interleukin-6	Sus scrofa	64-77
34727639-4	2022	The concentrations of serum triglyceride, total cholesterol and interleukin 6 were linearly increased (p<0.05) with increasing of dietary n-6:n-3 PUFA ratio, while that of high-density lipoprotein cholesterol tended to decrease (p = 0.062), and high-density lipoprotein cholesterol:low-density lipoprotein cholesterol ratio and leptin concentration was linearly decreased (p<0.05).	Nitrogen	138-140	leptin	Sus scrofa	328-334
34761234-2	2021	However, the innate capacity of autotrophic plants to produce carbon-related nutrients and nitrogen-related nutrients makes studying the TOR pathway difficult.	Nitrogen	91-99	target of rapamycin	Arabidopsis thaliana	137-140
34761234-4	2021	Exogenous carbon/nitrogen can be supplied to dissect the TOR pathway.	Nitrogen	17-25	target of rapamycin	Arabidopsis thaliana	57-60
34636540-6	2021	The obtained V-ZIF-8/PSF membrane shows a high CO2 permeability of 89.7 Barrer and a CO2/N2 selectivity of 30.0 that is stable over a period of 50 h. The CO2 permeability is enhanced about 11.8 times than that of the pure PSF membrane.	Nitrogen	89-91	insulin like growth factor binding protein 7	Homo sapiens	13-24
34643079-6	2021	The PIM-(durene-PEG/PPG) membranes show a high CO2 permeability of 350-669 Barrer and a high CO2/N2 selectivity of 33.5-40.3.	Nitrogen	97-99	serglycin	Homo sapiens	20-23
34636540-6	2021	The obtained V-ZIF-8/PSF membrane shows a high CO2 permeability of 89.7 Barrer and a CO2/N2 selectivity of 30.0 that is stable over a period of 50 h. The CO2 permeability is enhanced about 11.8 times than that of the pure PSF membrane.	Nitrogen	89-91	insulin like growth factor binding protein 7	Homo sapiens	222-225
34778038-1	2021	Ribophorin 1 (RPN1) is a major part of Oligosaccharyltransferase (OST) complex, which is vital for the N-linked glycosylation.	Nitrogen	103-104	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	39-64
34778038-1	2021	Ribophorin 1 (RPN1) is a major part of Oligosaccharyltransferase (OST) complex, which is vital for the N-linked glycosylation.	Nitrogen	103-104	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	66-69
34663735-2	2021	Our previous work identified Gid4 as a recognition component (N-recognin) of the Saccharomyces cerevisiae proteolytic system termed the proline (Pro)/N-degron pathway.	Nitrogen	150-151	glucose-induced degradation complex subunit VID24	Saccharomyces cerevisiae S288C	29-33
34707193-2	2021	The sp2 carbon atoms adjacent to nitrogen in the pyridine ring provide pi-acceptor which forms a complex with filled d-orbital of native oxides on Cu and Ru metal film.	Nitrogen	33-41	Sp2 transcription factor	Homo sapiens	4-7
34768843-8	2021	Furthermore, we found that the N-responsive and lateral-root-related genes TGA1 and NRT2.4 had NUC-binding sites in their promoter regions and that their expression was upregulated by NUC under N deficiency.	Nitrogen	31-32	bZIP transcription factor family protein	Arabidopsis thaliana	75-79
34699064-1	2022	Denitrifying woodchip bioreactors are a best management practice to reduce nitrate-nitrogen (NO3 -N) loading to surface waters from agricultural subsurface drainage.	Nitrogen	83-91	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
34768843-8	2021	Furthermore, we found that the N-responsive and lateral-root-related genes TGA1 and NRT2.4 had NUC-binding sites in their promoter regions and that their expression was upregulated by NUC under N deficiency.	Nitrogen	31-32	nitrate transporter 2.4	Arabidopsis thaliana	84-90
34119833-5	2021	The representative compound N2 is proved to induce the degradation of BRD4 upon irradiation.	Nitrogen	28-30	bromodomain containing 4	Danio rerio	70-74
34768798-9	2021	Under salt stress, alpha-TC demonstrated a stronger regulatory effect on carbon- and nitrogen-related metabolites reorganization and modulation of antioxidant patterns than gamma-TC.	Nitrogen	85-93	centroradiali	Arabidopsis thaliana	19-27
34822668-6	2021	In this study, the production of proinflammatory mediators, such as nitrogen oxide and prostaglandin E2, was induced by 1-NP in a concentration-dependent manner through the expression of iNOS and COX2.	Nitrogen	68-76	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	196-200
34671908-3	2022	The results indicated that the average reactive nitrogen (Nr) losses and GHG emissions from hybrid maize seed production were 53 kg N ha-1 and 8077 kg CO2 eq ha-1, respectively.	Nitrogen	48-56	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	158-162
34671908-3	2022	The results indicated that the average reactive nitrogen (Nr) losses and GHG emissions from hybrid maize seed production were 53 kg N ha-1 and 8077 kg CO2 eq ha-1, respectively.	Nitrogen	58-60	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	158-162
34733305-6	2021	(2) The increase in catalase (CAT) activity at 60, 80, and 100days after emergence (DAE), combined with decrease of malonaldehyde content at 60, 80, and 100 DAE, and the content of abscisic acid (ABA), all of these contributed to the delay of root senescence by low nitrogen treatment.	Nitrogen	266-274	catalase isozyme 1-like	Gossypium hirsutum	20-28
34733305-6	2021	(2) The increase in catalase (CAT) activity at 60, 80, and 100days after emergence (DAE), combined with decrease of malonaldehyde content at 60, 80, and 100 DAE, and the content of abscisic acid (ABA), all of these contributed to the delay of root senescence by low nitrogen treatment.	Nitrogen	266-274	catalase isozyme 1-like	Gossypium hirsutum	30-33
34722455-4	2021	HMP-TAPA, being rich in the nitrogen site, showed a high CO2 uptake of 106.7 mg/g with an IAST selectivity of 30.79 toward CO2 over N2.	Nitrogen	28-36	TAP binding protein	Homo sapiens	4-8
34182389-8	2021	The decrease in atmospheric N deposition was attributable mainly to decreased atmospheric ammonium (NH4+) deposition, which caused greater contribution of NO3- deposition to atmospheric N deposition.	Nitrogen	28-29	NBL1, DAN family BMP antagonist	Homo sapiens	155-158
34182389-8	2021	The decrease in atmospheric N deposition was attributable mainly to decreased atmospheric ammonium (NH4+) deposition, which caused greater contribution of NO3- deposition to atmospheric N deposition.	Nitrogen	186-187	NBL1, DAN family BMP antagonist	Homo sapiens	155-158
34722455-4	2021	HMP-TAPA, being rich in the nitrogen site, showed a high CO2 uptake of 106.7 mg/g with an IAST selectivity of 30.79 toward CO2 over N2.	Nitrogen	132-134	TAP binding protein	Homo sapiens	4-8
34681676-6	2021	MPhi functional data demonstrated that the adjunctive Tbeta4 treatment group significantly downregulated reactive nitrogen species (RNS) production and efferocytotic activity.	Nitrogen	114-122	transforming growth factor alpha regulated gene 3	Mus musculus	54-60
34648192-5	2022	RESULTS: The experiments in supersomes revealed CYP1A2 as the major CYP for 4-MAA N-demethylation and 4-FAA formation with CYP2C19 and CYP2D6 contributing to N-demethylation.	Nitrogen	82-83	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	68-71
34648192-5	2022	RESULTS: The experiments in supersomes revealed CYP1A2 as the major CYP for 4-MAA N-demethylation and 4-FAA formation with CYP2C19 and CYP2D6 contributing to N-demethylation.	Nitrogen	158-159	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	135-141
34605631-6	2021	Such excellent POD activity originates from high N-doping efficiency, protein-induced defective sites, and the intrinsic porous structure of HBF-1-C800, which provides abundantly accessible active sites and accelerates substrate diffusion simultaneously.	Nitrogen	49-50	forkhead box G1	Homo sapiens	141-146
34519476-5	2021	In this study, using high-resolution mass spectrometry, we have identified citrullination of Abeta in sporadic and familial AD brains by characterizing the tandem mass spectra of endogenous N-truncated citrullinated Abeta peptides.	Nitrogen	190-191	amyloid beta precursor protein	Homo sapiens	216-221
34558569-3	2021	In this study, a hollow carbon catalyst, NOC-1000-1, was prepared by pyrolysis of a mixture of a N-enriched Zn/bispyrozolate-based metal-organic framework and urea to replace the labile Pt-based catalysts for ORR.	Nitrogen	97-98	nocturnin	Homo sapiens	41-44
34685959-8	2021	Our recent study revealed that AtbZIP62 TF positively regulates the expression of AtPYD1 (Pyrimidine 1, a key gene of the de novo pyrimidine biosynthesis pathway know to share a common substrate with the N metabolic pathway).	Nitrogen	204-205	pyrimidine 1	Arabidopsis thaliana	82-88
34581118-12	2021	The formation of NO3-type water is mainly affected by domestic sewage, industrial wastewater, agricultural nitrogen fertilizer, septic tank outflows, and landfill leachate leakage.	Nitrogen	107-115	NBL1, DAN family BMP antagonist	Homo sapiens	17-20
34092405-8	2021	N-glycosylation defects of trypsin digested transferrin peptides were revealed by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS), and electrospray ionization MS verified the lack of N-glycans in transferrin.	Nitrogen	0-1	transferrin	Homo sapiens	44-55
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	77-85	carbonic anhydrase 14	Ovis aries	68-72
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	356-364	carbonic anhydrase 14	Ovis aries	68-72
34274480-12	2021	The amino terminal ends of both the CBLN1 and CBLN3 proteins contain three possible N-linked glycosylation sites.	Nitrogen	84-85	cerebellin 3 precursor	Homo sapiens	46-51
34738443-10	2021	These components acted on 189 common targets which were mainly involved in the cell responses to nitrogen compounds, organic cyclic compounds, and hormones, and enriched in the PI3 K-Akt signaling pathway, Foxo signaling pathway, and IL-17 signaling pathway.	Nitrogen	97-105	AKT serine/threonine kinase 1	Homo sapiens	183-186
34363947-4	2021	Cytokine (a mixture of IL-1beta, TNF-alpha, and IFN-gamma) treated AQP8 KD cells exhibited pronounced sensitivity to reactive oxygen and nitrogen species (ROS and RNS), resulting in a significant loss of beta-cell viability due to enhanced toxicity of the increased concentrations of H2O2 and hydroxyl radicals ( OH) in mitochondria of AQP8 KD cells.	Nitrogen	137-145	interleukin 1 alpha	Rattus norvegicus	23-31
34363947-4	2021	Cytokine (a mixture of IL-1beta, TNF-alpha, and IFN-gamma) treated AQP8 KD cells exhibited pronounced sensitivity to reactive oxygen and nitrogen species (ROS and RNS), resulting in a significant loss of beta-cell viability due to enhanced toxicity of the increased concentrations of H2O2 and hydroxyl radicals ( OH) in mitochondria of AQP8 KD cells.	Nitrogen	137-145	tumor necrosis factor	Rattus norvegicus	33-42
34363947-4	2021	Cytokine (a mixture of IL-1beta, TNF-alpha, and IFN-gamma) treated AQP8 KD cells exhibited pronounced sensitivity to reactive oxygen and nitrogen species (ROS and RNS), resulting in a significant loss of beta-cell viability due to enhanced toxicity of the increased concentrations of H2O2 and hydroxyl radicals ( OH) in mitochondria of AQP8 KD cells.	Nitrogen	137-145	aquaporin 8	Rattus norvegicus	67-71
34363947-4	2021	Cytokine (a mixture of IL-1beta, TNF-alpha, and IFN-gamma) treated AQP8 KD cells exhibited pronounced sensitivity to reactive oxygen and nitrogen species (ROS and RNS), resulting in a significant loss of beta-cell viability due to enhanced toxicity of the increased concentrations of H2O2 and hydroxyl radicals ( OH) in mitochondria of AQP8 KD cells.	Nitrogen	137-145	aquaporin 8	Rattus norvegicus	336-340
34384998-7	2021	Using a molecular dynamic simulation approach, we identified the N2, methyl of C1 and benzene ring of harmine interact with Zn2+ (2.4 A), His205 (2.4 A) and His211 (2.4 A) as well as Val163 (2.7 A) at the active site of MMP-3, respectively, and thus conferred a striking specific binding advantage.	Nitrogen	65-67	matrix metallopeptidase 3	Homo sapiens	220-225
34127537-6	2021	Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls.	Nitrogen	50-51	CD79a molecule	Homo sapiens	84-88
34127537-7	2021	Results: Multiple structural features of N-glycosylation of IgA1 and IgA2 were associated with IgAN and glomerular function in our cross-sectional study.	Nitrogen	41-42	CD79a molecule	Homo sapiens	69-73
34087531-1	2021	Transport and transformation processes of nitrogen in the soil are an essential part of understanding the relationship between agricultural input and nitrate (NO3-) concentrations in groundwater.	Nitrogen	42-50	NBL1, DAN family BMP antagonist	Homo sapiens	159-162
34087531-14	2021	This assessment of nitrogen degradation in the vadose zone will be a useful tool for NO3- levels forecast in groundwater.	Nitrogen	19-27	NBL1, DAN family BMP antagonist	Homo sapiens	85-88
34128546-7	2021	WRKY46 is shown to directly bind to the promoters of the NUDX9 and IAA-conjugating genes (GH3.1, GH3.6, UGT75D1, UGT84B2) and inhibits their transcription, thus positively regulating free IAA content and stabilizing protein N-glycosylation, leading to an inhibition of NH4 + efflux in the root elongation zone (EZ).	Nitrogen	224-225	WRKY DNA-binding protein 46	Arabidopsis thaliana	0-6
34500180-7	2021	Based on urban land use grouping, nutrient elements could predict dCH4 well in rivers draining higher urban areas (urban >= 2%), which also reflected the lateral input of pollutants (TN, ammonia nitrogen, and total phosphorus).	Nitrogen	195-203	COP9 signalosome subunit 4	Drosophila melanogaster	66-70
34526412-10	2021	Urinary L-FABP was significantly correlated with serum creatinine (r=0.4674, P<0.01), urea nitrogen (r=0.4907, P<0.01), urine specific gravity (r=-0.5100, P<0.01), and urine protein/creatinine ratio (r=0.7216, P<0.01), but not with serum ALT.	Nitrogen	91-99	fatty acid binding protein 1	Homo sapiens	8-14
34544850-5	2021	We demonstrate that this autoimmunity is the result of two mutations: 1) a mutation in the GCS1 gene that disrupts N-glycosylation of extracellular matrix proteins covering the fat body, and 2) a mutation in the Drosophila Janus Kinase ortholog that causes precocious activation of hemocytes.	Nitrogen	115-116	Glucosidase 1	Drosophila melanogaster	91-95
34638794-0	2021	PDF1.5 Enhances Adaptation to Low Nitrogen Levels and Cadmium Stress.	Nitrogen	34-42	plant defensin 1.5	Arabidopsis thaliana	0-6
34638794-2	2021	Here, we determined the involvement of Arabidopsis thaliana PLANT DEFENSIN 1 gene AtPDF1.5 in the adaptation to low nitrogen (LN) levels and cadmium (Cd) stress.	Nitrogen	116-124	plant defensin 1.5	Arabidopsis thaliana	82-90
34565765-8	2021	PCSK7 concentration was negatively correlated with age and blood urea nitrogen and was positively correlated with body mass index (BMI) and levels of gamma-glutamyl transpeptidase (gammaGTP), triglycerides and fatty liver index (FLI), which is calculated by BMI, waist circumference and levels of gammaGTP and triglycerides, as a noninvasive and simple predictor of NAFLD.	Nitrogen	70-78	proprotein convertase subtilisin/kexin type 7	Homo sapiens	0-5
34464118-3	2021	Our experiments and density functional theory calculations indicate that the Co atom fixated into the nitrogen pots of g-C3N4 serves as the main active site, enabling dissociation of the adsorbed PAA and conversion of the coordinated Co(II) to Co(IV) via a unique two-electron transfer mechanism.	Nitrogen	102-110	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	234-240
34515997-3	2022	It was found that NO3 - ion is easily reduced into NO2 - and NOx and then further into N2 and NH3 (in the form of NH4 + ) in the process.	Nitrogen	87-89	NBL1, DAN family BMP antagonist	Homo sapiens	18-21
34575794-5	2021	However, the gene expression of FRE1 and CTR1 was downregulated by nitrogen starvation.	Nitrogen	67-75	ferric/cupric-chelate reductase	Saccharomyces cerevisiae S288C	32-36
34575794-8	2021	Mac1 was downregulated dramatically under nitrogen starvation, and treatment with MG132, which is an inhibitor of proteasome-dependent protein degradation, partially attenuated the downregulation of Mac1.	Nitrogen	42-50	Mac1p	Saccharomyces cerevisiae S288C	0-4
34575794-8	2021	Mac1 was downregulated dramatically under nitrogen starvation, and treatment with MG132, which is an inhibitor of proteasome-dependent protein degradation, partially attenuated the downregulation of Mac1.	Nitrogen	42-50	Mac1p	Saccharomyces cerevisiae S288C	199-203
34575794-9	2021	Taken together, these results suggest that nitrogen starvation downregulates the high-affinity iron uptake system by degrading Mac1 in a proteasome-dependent manner and eventually downregulates copper metabolism.	Nitrogen	43-51	Mac1p	Saccharomyces cerevisiae S288C	127-131
34646384-6	2021	A survival screen, to determine if glycan remodeling enzymes are redundant, identified MGAT1 and NGLY1, essential components of the N-glycosylation/degradation pathway, as highly relevant within this in vitro screening.	Nitrogen	132-133	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	87-92
34374528-6	2021	The high conjugation between the pz-lone pair of the tricoordinated sp2 hybridized N atom and the B N pi-system results in a particularly long B N double bond distance.	Nitrogen	83-84	Sp2 transcription factor	Homo sapiens	68-71
34374528-7	2021	Taking advantage of the pendant lone pair of the dicoordinated sp2 hybridized N atom, the iminoborane-NHC adduct gives access to NHC-stabilized borenium cation 3 through the reaction with trimethylsilyl triflate (Me3SiOTf) or to the gallium adduct 4 by reacting with GaCl3.	Nitrogen	78-79	Sp2 transcription factor	Homo sapiens	63-66
34459583-7	2021	The N atoms in the polynitrides hybridize in the sp2 state, for which the hybrid orbitals are constructed by the sigma bond or lone electronic pair.	Nitrogen	4-5	Sp2 transcription factor	Homo sapiens	49-52
34765394-3	2021	The abnormal N-glycosylation profile with an elevation of asialotransferrin and disialotransferrin, typical of CDG type I, is assessable by transferrin isoelectrofocusing.	Nitrogen	13-14	transferrin	Homo sapiens	140-151
34102366-1	2021	We prepared a single-atom Fe catalyst supported on an oxygen-doped, nitrogen-rich carbon support (SAFe-OCN) for degrading a broad spectrum of contaminants of emerging concern (CECs) by activating peroxides such as peroxymonosulfate (PMS).	Nitrogen	68-76	bone gamma-carboxyglutamate protein	Homo sapiens	103-106
34102366-4	2021	Specifically, SAFe-OCN, with a catalytic center of Fe coordinated with both nitrogen and oxygen (FeNxO4-x), showed 5.13-times increased phenol degradation kinetics upon activating PMS compared to the catalyst where Fe was only coordinated with nitrogen (FeN4).	Nitrogen	76-84	bone gamma-carboxyglutamate protein	Homo sapiens	19-22
34102366-4	2021	Specifically, SAFe-OCN, with a catalytic center of Fe coordinated with both nitrogen and oxygen (FeNxO4-x), showed 5.13-times increased phenol degradation kinetics upon activating PMS compared to the catalyst where Fe was only coordinated with nitrogen (FeN4).	Nitrogen	244-252	bone gamma-carboxyglutamate protein	Homo sapiens	19-22
34313361-2	2021	Here, we utilize the Schottky barrier-induced surface electric field, by the construction of high density of electron-deficient Ni nanoparticles inside nitrogen-rich carbons, to facilitate the enrichment and fixation of all NO x - anions on the electrode surface, including NO 3 - and NO 2 - , and thus ensure the final selectivity to NH 3 .	Nitrogen	152-160	NBL1, DAN family BMP antagonist	Homo sapiens	274-278
34543530-6	2021	In order to characterize the state of vascular tone, a coefficient was used that represents the ratio of the concentration of nitrogen oxide (mumol/L) to endothelin-1 (pg/ml) (NOx/ET-1).	Nitrogen	126-134	endothelin 1	Homo sapiens	180-184
34568593-12	2021	Zero tillage treatment with application of 5 t ha-1 of residue and 80 kg N ha-1 was the most dominant and most profitable compared to the other treatments.	Nitrogen	73-74	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	75-79
34304009-2	2021	NNMT is an enzyme that catalyzes the N-methylation of the endogenous substrate nicotinamide, as well as exogenous xenobiotics.	Nitrogen	37-38	nicotinamide N-methyltransferase	Rattus norvegicus	0-4
34309217-2	2021	Herein, a rapid construction of novel BF2 complexes with N,O-bidentate ligands by using Cu(BF4 )2  6H2 O as a catalyst and BF2 source is disclosed, which avoids the need for pre-composing the N,O-bidentate ligands and features a broad substrate scope and a high tolerance level for sensitive functional groups.	Nitrogen	57-58	forkhead box G1	Homo sapiens	38-41
34502529-0	2021	Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways.	Nitrogen	6-14	erb-b2 receptor tyrosine kinase 2	Homo sapiens	71-75
34502529-0	2021	Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways.	Nitrogen	6-14	mitogen-activated protein kinase 8	Homo sapiens	115-118
34502529-0	2021	Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways.	Nitrogen	6-14	mitogen-activated protein kinase 3	Homo sapiens	123-127
34502529-0	2021	Novel Nitrogen-Based Chalcone Analogs Provoke Substantial Apoptosis in HER2-Positive Human Breast Cancer Cells via JNK and ERK1/ERK2 Signaling Pathways.	Nitrogen	6-14	mitogen-activated protein kinase 1	Homo sapiens	128-132
34502536-4	2021	Long-term exposure to TiO2 nanoparticles co-doped with 1% of iron and nitrogen led to the alteration of p53 protein activity and the gene expression controlled by this suppressor (NF-kB and mdm2), DNA damage, cell cycle disruptions at the G2/M and S phases, and lysosomal membrane permeabilization and the subsequent release of cathepsin B, triggering the intrinsic pathway of apoptosis in a Bax- and p53-independent manner.	Nitrogen	70-78	tumor protein p53	Homo sapiens	104-107
34502536-4	2021	Long-term exposure to TiO2 nanoparticles co-doped with 1% of iron and nitrogen led to the alteration of p53 protein activity and the gene expression controlled by this suppressor (NF-kB and mdm2), DNA damage, cell cycle disruptions at the G2/M and S phases, and lysosomal membrane permeabilization and the subsequent release of cathepsin B, triggering the intrinsic pathway of apoptosis in a Bax- and p53-independent manner.	Nitrogen	70-78	BCL2 associated X, apoptosis regulator	Homo sapiens	392-395
34502536-4	2021	Long-term exposure to TiO2 nanoparticles co-doped with 1% of iron and nitrogen led to the alteration of p53 protein activity and the gene expression controlled by this suppressor (NF-kB and mdm2), DNA damage, cell cycle disruptions at the G2/M and S phases, and lysosomal membrane permeabilization and the subsequent release of cathepsin B, triggering the intrinsic pathway of apoptosis in a Bax- and p53-independent manner.	Nitrogen	70-78	tumor protein p53	Homo sapiens	401-404
34174328-8	2021	Furthermore, we characterized a serine site-directed mutant of the Mpro bound to its endogenous N and C-terminal residues during dimeric association stage of the maturation process.	Nitrogen	96-97	NEWENTRY	Severe acute respiratory syndrome-related coronavirus	67-71
34180113-0	2021	Enzymatic Tailoring in Luzopeptin Biosynthesis Involves Cytochrome P450-Mediated Carbon-Nitrogen Bond Desaturation for Hydrazone Formation.	Nitrogen	88-96	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	56-71
34180113-3	2021	Significantly, we revealed a multitasking cytochrome P450 enzyme that catalyzes four consecutive oxidations including the highly unusual carbon-nitrogen bond desaturation, forming the hydrazone-bearing 4-OH-Thp residues.	Nitrogen	144-152	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	42-57
34414755-4	2021	Compared to both the NPK and BC+NPK treatments, N-BC+PK significantly reduced the cumulative N2O-N emissions and NH3-N volatilization, as well as the total gaseous nitrogen loss from the soil (P<0.05).	Nitrogen	164-172	tachykinin precursor 1	Homo sapiens	32-35
34309217-2	2021	Herein, a rapid construction of novel BF2 complexes with N,O-bidentate ligands by using Cu(BF4 )2  6H2 O as a catalyst and BF2 source is disclosed, which avoids the need for pre-composing the N,O-bidentate ligands and features a broad substrate scope and a high tolerance level for sensitive functional groups.	Nitrogen	57-58	forkhead box G1	Homo sapiens	123-126
34243073-1	2021	We herein report a new synthetic route for a series of unreported 1,4-dihydropyrazolo(4,3-b)indoles (6-8) via deoxygenation of o-nitrophenyl-substituted N-aryl pyrazoles and subsequent intramolecular (sp2)-N bond formation under microwave irradiation expedite modified Cadogan condition.	Nitrogen	206-207	Sp2 transcription factor	Homo sapiens	201-204
34089542-8	2021	This caused a shifted dominance from NO3 - to NH4 + in N deposition.	Nitrogen	55-56	NBL1, DAN family BMP antagonist	Homo sapiens	37-40
34117813-5	2021	GnT-V medicated N-glycosylation on VE-cadherin regulates the dissociation of VE-cadherin/beta-catenin complex to modulate the monocyte adhesion, but GnT-V overexpression can not rescue monocyte adhesion induced by IL-1beta.	Nitrogen	16-17	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-5
34117813-5	2021	GnT-V medicated N-glycosylation on VE-cadherin regulates the dissociation of VE-cadherin/beta-catenin complex to modulate the monocyte adhesion, but GnT-V overexpression can not rescue monocyte adhesion induced by IL-1beta.	Nitrogen	16-17	cadherin 5	Homo sapiens	35-46
34117813-5	2021	GnT-V medicated N-glycosylation on VE-cadherin regulates the dissociation of VE-cadherin/beta-catenin complex to modulate the monocyte adhesion, but GnT-V overexpression can not rescue monocyte adhesion induced by IL-1beta.	Nitrogen	16-17	cadherin 5	Homo sapiens	77-88
34089542-10	2021	Meanwhile, non-fossil fuel NOx sources (biomass burning, microbial N cycles) contributed generally more than fossil fuel NOx sources (vehicle exhausts, coal combustion) to the elevation of NO3 - deposition.	Nitrogen	67-68	NBL1, DAN family BMP antagonist	Homo sapiens	189-192
34331945-4	2021	MPO generates the oxidants hypochlorous acid and nitrogen dioxide, which can lead to post-translational modification of PON1, including tyrosine modifications that inhibit PON1 activity.	Nitrogen	49-57	myeloperoxidase	Homo sapiens	0-3
34331945-4	2021	MPO generates the oxidants hypochlorous acid and nitrogen dioxide, which can lead to post-translational modification of PON1, including tyrosine modifications that inhibit PON1 activity.	Nitrogen	49-57	paraoxonase 1	Homo sapiens	120-124
34331945-4	2021	MPO generates the oxidants hypochlorous acid and nitrogen dioxide, which can lead to post-translational modification of PON1, including tyrosine modifications that inhibit PON1 activity.	Nitrogen	49-57	paraoxonase 1	Homo sapiens	172-176
34331945-5	2021	Nitrogen dioxide also drives lipid peroxidation, leading to the formation of reactive lipid dicarbonyls such as malondialdehyde (MDA) and isolevuglandins (IsoLGs) which modify HDL and could inhibit PON1 activity.	Nitrogen	0-8	paraoxonase 1	Homo sapiens	198-202
34333551-2	2021	Here, we show that ELOngation of Very Long chain fatty acids protein 4 (ELOVL4), a rate-limiting enzyme in the biosynthesis of very-long polyunsaturated fatty acids (n-3, >=28 C), is expressed and transcriptionally repressed by the oncogene MYCN in neuroblastoma cells.	Nitrogen	166-167	ELOVL fatty acid elongase 4	Homo sapiens	72-78
34463135-6	2021	High plasma CX3CL1 was negatively correlated with platelet count (r = -0.5844, p < 0.0001) and positively correlated with blood urea nitrogen (r = 0.3668, p = 0.0039), creatinine (r = 0.42, p = 0.0008), and white blood cells (r = 0.2646, p = 0.0411).	Nitrogen	133-141	C-X3-C motif chemokine ligand 1	Homo sapiens	12-18
34471165-4	2021	The predicted values of total soil NO3--N and NH4+-N nitrogen are 10 kg ha-1 and 5 kg ha-1 higher than the observed values.	Nitrogen	53-61	Rho GTPase activating protein 45	Homo sapiens	72-82
34471165-4	2021	The predicted values of total soil NO3--N and NH4+-N nitrogen are 10 kg ha-1 and 5 kg ha-1 higher than the observed values.	Nitrogen	53-61	Rho GTPase activating protein 45	Homo sapiens	86-90
34733488-0	2021	Small-interfering RNA for c-Jun attenuates cell death by preventing JNK-dependent PARP1 cleavage and DNA fragmentation in nitrogen mustard-injured immortalized human bronchial epithelial cells.	Nitrogen	122-130	mitogen-activated protein kinase 8	Homo sapiens	68-71
34733488-3	2021	Here, we report that JNK/c-Jun was activated in immortalized human bronchial epithelial (HBE) cells exposed to a lethal dose (20 muM) of nitrogen mustard (NM, a sulfur mustard analog).	Nitrogen	137-145	mitogen-activated protein kinase 8	Homo sapiens	21-24
34433568-1	2021	The SLC15 family of proton-coupled solute carriers PepT1 and PepT2 play a central role in human physiology as the principal route for acquiring and retaining dietary nitrogen.	Nitrogen	166-174	solute carrier family 15 member 1	Homo sapiens	51-56
34502227-6	2021	Thus, this review aimed to present literature data that show its ability to form a membrane complex with CD63 and beta1-integrin, and point to N-glycosylation as a potential regulatory mechanism of the functions exerted by TIMP-1.	Nitrogen	143-144	TIMP metallopeptidase inhibitor 1	Homo sapiens	223-229
34512567-7	2021	The variations of fungal alpha-diversity, community composition, and the relative abundance of major phyla, genera, and functional guilds were mainly correlated with soil pH and NO3 --N concentration, and these correlations were much stronger under short-term than long-term N addition.	Nitrogen	184-185	NBL1, DAN family BMP antagonist	Homo sapiens	178-181
34512567-7	2021	The variations of fungal alpha-diversity, community composition, and the relative abundance of major phyla, genera, and functional guilds were mainly correlated with soil pH and NO3 --N concentration, and these correlations were much stronger under short-term than long-term N addition.	Nitrogen	275-276	NBL1, DAN family BMP antagonist	Homo sapiens	178-181
34513728-5	2021	Furthermore, when the M-N interaction was disrupted via certain rationally designed peptides, the PDK1-PKB/Akt signaling was restored, and the boosting activity of N on the M-triggered apoptosis was abolished.	Nitrogen	24-25	AKT serine/threonine kinase 1	Homo sapiens	103-106
34513728-5	2021	Furthermore, when the M-N interaction was disrupted via certain rationally designed peptides, the PDK1-PKB/Akt signaling was restored, and the boosting activity of N on the M-triggered apoptosis was abolished.	Nitrogen	24-25	AKT serine/threonine kinase 1	Homo sapiens	107-110
34572965-3	2021	Reactive oxygen and nitrogen species (RONS) promote corticosteroid insensitivity by disrupting glucocorticoid receptor (GR) signaling, leading to the sustained activation of pro-inflammatory pathways in immune and airway structural cells.	Nitrogen	20-28	nuclear receptor subfamily 3 group C member 1	Homo sapiens	95-118
34572965-3	2021	Reactive oxygen and nitrogen species (RONS) promote corticosteroid insensitivity by disrupting glucocorticoid receptor (GR) signaling, leading to the sustained activation of pro-inflammatory pathways in immune and airway structural cells.	Nitrogen	20-28	nuclear receptor subfamily 3 group C member 1	Homo sapiens	120-122
34433568-1	2021	The SLC15 family of proton-coupled solute carriers PepT1 and PepT2 play a central role in human physiology as the principal route for acquiring and retaining dietary nitrogen.	Nitrogen	166-174	solute carrier family 15 member 2	Homo sapiens	61-66
34456583-0	2021	Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19).	Nitrogen	11-19	albumin	Homo sapiens	29-36
34456583-1	2021	Purpose: We sought to explore the prognostic value of blood urea nitrogen (BUN) to serum albumin ratio (BAR) and further develop a prediction model for critical illness in COVID-19 patients.	Nitrogen	65-73	albumin	Homo sapiens	89-96
34414940-6	2021	Amounts of circulating GRP78 correlated directly with serum fasting c-peptide, cystatin-c (Cys-c), creatinine (Cr), blood urea nitrogen (BUN), and uric acid, and inversely with glomerular filtration rates.	Nitrogen	127-135	heat shock protein family A (Hsp70) member 5	Homo sapiens	23-28
34471466-11	2021	Treatment of mice with PSF-SOD1 inhibited CP-induced serum creatinine, blood urea nitrogen elevation, and JNK/p38 MAPK activation.	Nitrogen	82-90	interleukin 3	Mus musculus	23-26
34471466-11	2021	Treatment of mice with PSF-SOD1 inhibited CP-induced serum creatinine, blood urea nitrogen elevation, and JNK/p38 MAPK activation.	Nitrogen	82-90	superoxide dismutase 1, soluble	Mus musculus	27-31
34483834-0	2021	Role of N-Linked Glycosylation in PKR2 Trafficking and Signaling.	Nitrogen	8-9	prokineticin receptor 2	Homo sapiens	34-38
34214466-5	2021	The structures reveal that ZYG11B and ZER1 utilize their armadillo (ARM) repeats forming a deep and narrow cavity to engage mainly the first four residues of Gly/N-degrons.	Nitrogen	162-163	zyg-11 related cell cycle regulator	Homo sapiens	38-42
34408222-5	2021	The NO3- in surface water from the mid-upper reaches of the drainage basin mainly originates from soil nitrogen (SN) and chemical fertilizer (CF), with contribution rates of 48% and 32%, respectively, and the NO3- in downstream areas mainly originates from CF and manure and sewage (MS), with contribution rates of 48% and 33%, respectively.	Nitrogen	103-111	NBL1, DAN family BMP antagonist	Homo sapiens	4-7
34380733-6	2021	Mechanistically, we find that CWH43 deletion leads to decreased N-glycosylation of L1CAM, decreased association of L1CAM with cell membrane lipid microdomains, increased L1CAM cleavage by plasmin, and increased shedding of cleaved L1CAM in the cerebrospinal fluid.	Nitrogen	64-65	L1 cell adhesion molecule	Homo sapiens	83-88
34483834-4	2021	Here we identify 2 N-linked glycosylation sites within the N-terminal region of PKR2 and demonstrate that glycosylation of PKR2 at position 27 is important for its plasma membrane localization and signaling.	Nitrogen	19-20	prokineticin receptor 2	Homo sapiens	80-84
34483834-4	2021	Here we identify 2 N-linked glycosylation sites within the N-terminal region of PKR2 and demonstrate that glycosylation of PKR2 at position 27 is important for its plasma membrane localization and signaling.	Nitrogen	19-20	prokineticin receptor 2	Homo sapiens	123-127
34421841-1	2021	Woodchip bioreactors are increasingly used to remove nitrate (NO3 -) from agricultural drainage water in order to protect aquatic ecosystems from excess nitrogen.	Nitrogen	153-161	NBL1, DAN family BMP antagonist	Homo sapiens	62-65
34443398-0	2021	Magnetic Nitrogen-Doped Porous Carbon Nanocomposite for Pb(II) Adsorption from Aqueous Solution.	Nitrogen	9-17	submaxillary gland androgen regulated protein 3B	Homo sapiens	56-62
34132586-6	2021	Third, we deleted URE2 coding for a transcriptional regulator in charge of nitrogen catabolite repression (NCR) to induce lipid accumulation regardless of carbon to nitrogen ratio in culture media.	Nitrogen	75-83	glutathione peroxidase	Saccharomyces cerevisiae S288C	18-22
34132586-10	2021	URE2, a bifunctional protein that is involved in both nitrogen catabolite repression and oxidative stress response, was identified and demonstrated correlation to squalene production.	Nitrogen	54-62	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-4
34292709-5	2021	Supported by an optimal chiral ligand, the Co(II)-based metalloradical system, which operates under mild conditions, is capable of 1,4-C-H alkylation of alpha-aryldiazoketones with varied electronic and steric properties to construct chiral alpha,beta-disubstituted cyclobutanones in good to high yields with high diastereoselectivities and enantioselectivities, generating dinitrogen as the only byproduct.	Nitrogen	374-384	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	43-49
34354228-0	2021	The structure of an archaeal oligosaccharyltransferase provides insight into the strict exclusion of proline from the N-glycosylation sequon.	Nitrogen	118-119	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	29-54
34354228-1	2021	Oligosaccharyltransferase (OST) catalyzes oligosaccharide transfer to the Asn residue in the N-glycosylation sequon, Asn-X-Ser/Thr, where Pro is strictly excluded at position X.	Nitrogen	93-94	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	0-25
34354228-1	2021	Oligosaccharyltransferase (OST) catalyzes oligosaccharide transfer to the Asn residue in the N-glycosylation sequon, Asn-X-Ser/Thr, where Pro is strictly excluded at position X.	Nitrogen	93-94	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	27-30
34353366-10	2021	RESULTS: Plasma creatinine, blood urea nitrogen, and cystatin C were decrease by MSCp infusion as well as kidney injury molecule (KIM)-1 on histological kidney sections.	Nitrogen	39-47	musculin	Rattus norvegicus	81-85
34351097-0	2021	Glutathione (GSH) and superoxide dismutase (SOD) levels among junior high school students induced by indoor particulate matter 2.5 (PM2.5) and nitrogen dioxide (NO2) exposure.	Nitrogen	143-151	superoxide dismutase 1	Homo sapiens	44-47
34293862-3	2021	ESI in-source CID induces N-Calpha bond dissociation in substituted phenethylamines lacking a beta-hydroxy group to produce fragment ions with a spiro(2.5)octadienylium motif.	Nitrogen	26-27	calcitonin/calcitonin-related polypeptide, alpha	Mus musculus	28-34
34279079-1	2021	Three new thiosemicarbazones (TSCs) HL1-HL3 as triapine analogues bearing a redox-active phenolic moiety at the terminal nitrogen atom were prepared.	Nitrogen	121-129	asialoglycoprotein receptor 1	Homo sapiens	36-43
34101954-4	2021	The selectivity for Abeta was dependent on the position of nitrogen in the heterocyclic compounds, and the ability to bind Abeta was shown to be reduced when introducing anionic substituents on the thiophene backbone.	Nitrogen	59-67	amyloid beta precursor protein	Homo sapiens	20-25
34101954-4	2021	The selectivity for Abeta was dependent on the position of nitrogen in the heterocyclic compounds, and the ability to bind Abeta was shown to be reduced when introducing anionic substituents on the thiophene backbone.	Nitrogen	59-67	amyloid beta precursor protein	Homo sapiens	123-128
34225858-8	2021	Vitronectin was competitively (statistically significant, p < 0.05) adsorbed after argon and combination treatment whereas nitrogen treatment led to the competitive adsorption of fibronectin (statistically significant, p < 0.05).	Nitrogen	123-131	fibronectin 1	Homo sapiens	179-190
34341353-7	2021	Notably, N-induced lung injury and cytokine production are blocked by MCC950 (a specific inhibitor of NLRP3) and Ac-YVAD-cmk (an inhibitor of caspase-1).	Nitrogen	9-10	C-X-C motif chemokine ligand 9	Homo sapiens	121-124
34341353-7	2021	Notably, N-induced lung injury and cytokine production are blocked by MCC950 (a specific inhibitor of NLRP3) and Ac-YVAD-cmk (an inhibitor of caspase-1).	Nitrogen	9-10	caspase 1	Homo sapiens	142-151
34212211-0	2021	Nitrogen-doped carbon quantum dots fabricated from cellulolytic enzyme lignin and its application to the determination of cytochrome c and trypsin.	Nitrogen	0-8	cytochrome c, somatic	Homo sapiens	122-134
34212211-1	2021	A sensitive and effective strategy for the detection of cytochrome c (Cyt c) and trypsin was developed using biomass nitrogen-doped carbon quantum dots (N-CQDs) as the fluorescence probe.	Nitrogen	117-125	cytochrome c, somatic	Homo sapiens	56-68
34212211-1	2021	A sensitive and effective strategy for the detection of cytochrome c (Cyt c) and trypsin was developed using biomass nitrogen-doped carbon quantum dots (N-CQDs) as the fluorescence probe.	Nitrogen	117-125	cytochrome c, somatic	Homo sapiens	70-75
34278443-3	2021	The levels of blood urea nitrogen (BUN) and serum creatinine (SCR) were increased by Ang II in the rats, and these were reversed by sinigrin in a dose-dependent manner.	Nitrogen	25-33	angiotensinogen	Rattus norvegicus	85-91
34341769-5	2021	CD209L contains two N-glycosylation sequons, at sites N92 and N361, but we determined that only site N92 is occupied.	Nitrogen	20-21	C-type lectin domain family 4 member M	Homo sapiens	0-6
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	22-23	nitrate reductase 1	Arabidopsis thaliana	102-119
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	36-37	nitrate reductase 1	Arabidopsis thaliana	102-119
34539109-10	2021	Protein-protein interaction (PPI) network analysis revealed three key biological processes regulated by TERF1, including nitrogen metabolism, light related processes and mitosis.	Nitrogen	121-129	ethylene-responsive transcription factor 1	Solanum lycopersicum	104-109
34341769-6	2021	Removal of the N-glycosylation at this site enhances the binding of S-RBD with CD209L.	Nitrogen	15-16	C-type lectin domain family 4 member M	Homo sapiens	79-85
34440653-2	2021	When reactive oxygen species (ROS) or reactive nitrogen species (RNS) are detected, Nrf2 translocates from the cytoplasm into the nucleus and binds to the antioxidant response element (ARE), which regulates the expression of antioxidant and anti-inflammatory genes.	Nitrogen	47-55	NFE2 like bZIP transcription factor 2	Homo sapiens	84-88
34360932-6	2021	N-glycosylation, especially at N52, and its processing in the Golgi were critical for the sorting and expression of CD24 at the plasma membrane of HEK293T and basal B type cells, but not of MCF-7 cells.	Nitrogen	0-1	CD24 molecule	Homo sapiens	116-120
34360932-7	2021	In conclusion, our study highlights the contribution of N-glycosylation for the subcellular localization of CD24.	Nitrogen	56-57	CD24 molecule	Homo sapiens	108-112
34360932-8	2021	Aberrant N-glycosylation at N52 of CD24 could account for the lack of CD24 expression at the cell surface of basal B breast cancer cells.	Nitrogen	9-10	CD24 molecule	Homo sapiens	35-39
34360932-8	2021	Aberrant N-glycosylation at N52 of CD24 could account for the lack of CD24 expression at the cell surface of basal B breast cancer cells.	Nitrogen	9-10	CD24 molecule	Homo sapiens	70-74
34305014-8	2021	RESULTS: Neutrophils, haematocrit, serum calcium, and blood urea nitrogen were predictors of POF in ABP.	Nitrogen	65-73	POF1B actin binding protein	Homo sapiens	93-96
34360651-7	2021	Nitrated derivatives of Trp and Tyr were formed in the 8 kHz (nitrogen) mode, elevating the p16 mRNA expression and senescence-associated ss-Galactosidase staining.	Nitrogen	62-70	cyclin dependent kinase inhibitor 2A	Homo sapiens	92-95
34336790-1	2021	Haptoglobin (Hp) is one of the acute-phase response proteins secreted by the liver, and its aberrant N-glycosylation was previously reported in hepatocellular carcinoma (HCC).	Nitrogen	101-102	haptoglobin	Homo sapiens	0-11
34232013-2	2021	Herein, in situ synthesis of nano-GeP confined in nitrogen-doped carbon (GeP@NC) fibers was designed and performed via coaxial electrospinning followed by a phosphating process.	Nitrogen	50-58	granulin precursor	Homo sapiens	34-37
34232013-2	2021	Herein, in situ synthesis of nano-GeP confined in nitrogen-doped carbon (GeP@NC) fibers was designed and performed via coaxial electrospinning followed by a phosphating process.	Nitrogen	50-58	granulin precursor	Homo sapiens	73-76
34284133-12	2021	Moreover, the N-glycosylation is essential for the function and secretion of AMCase.	Nitrogen	14-15	chitinase acidic	Homo sapiens	77-83
34287525-7	2021	Nitrogen applied at the rate of 180 kg ha-1 increased pods plant-1, seed pod, seed filling duration, seed weight, biological yield and seed yield.	Nitrogen	0-8	Rho GTPase activating protein 45	Homo sapiens	39-43
34497692-11	2021	Nevertheless, the mean percentage of Neu N-positive cells was significantly higher in differentiated cells with embryoid bodies" source, especially in the presence of SHH than other groups (P <= 0.05).	Nitrogen	41-42	erb-b2 receptor tyrosine kinase 2	Homo sapiens	37-40
34181425-0	2021	Atom Transfer Radical Polymerization-Inspired Room Temperature (sp3)C-N Coupling.	Nitrogen	70-71	Sp3 transcription factor	Homo sapiens	64-67
34238104-6	2021	RESULTS: LPS-induced AKI mice injected with the miR-494 antagomir showed reduced blood urea nitrogen (BUN) and serum creatinine (Cr) with improved kidney histopathology.	Nitrogen	92-100	microRNA 494	Mus musculus	48-55
34160210-5	2021	The pi-donating amide group is formally sp2 hybridized with a planar nitrogen to give a strongly bound five-membered chelating anion.	Nitrogen	69-77	Sp2 transcription factor	Homo sapiens	40-43
34277562-1	2021	Herein, selenium and nitrogen co-doped carbon quantum dots (Se/N-CQDs) were hydrothermally synthesized by using citric acid, histidine, and sodium selenite, which had sp3 and sp2 hybridized carbon atoms and showed excitation-dependent fluorescence behavior.	Nitrogen	21-29	Sp3 transcription factor	Homo sapiens	167-170
34277562-1	2021	Herein, selenium and nitrogen co-doped carbon quantum dots (Se/N-CQDs) were hydrothermally synthesized by using citric acid, histidine, and sodium selenite, which had sp3 and sp2 hybridized carbon atoms and showed excitation-dependent fluorescence behavior.	Nitrogen	21-29	Sp2 transcription factor	Homo sapiens	175-178
34215809-6	2021	Considering both economic and environmental benefits, 10 t ha-1 biochar combined with 144 kg ha-1 nitrogen was the best combination to restore crop productivity and soil quality, and to achieve nitrogen decreasing and benefit increasing.	Nitrogen	98-106	Rho GTPase activating protein 45	Homo sapiens	93-97
34214084-14	2021	iNOS-expressing microglia release cytokines and reactive oxygen/ nitrogen species which may further contribute to the white matter damage observed in this model.	Nitrogen	65-73	nitric oxide synthase 2, inducible	Mus musculus	0-4
34276717-3	2021	However, excessive nitrogen use has an enormous negative impact on ecosystems and human health through the emission of intense greenhouse gases, such as nitric oxide derived from the nitrate (NO3 -) assimilation cascade.	Nitrogen	19-27	NBL1, DAN family BMP antagonist	Homo sapiens	192-195
34215809-6	2021	Considering both economic and environmental benefits, 10 t ha-1 biochar combined with 144 kg ha-1 nitrogen was the best combination to restore crop productivity and soil quality, and to achieve nitrogen decreasing and benefit increasing.	Nitrogen	194-202	Rho GTPase activating protein 45	Homo sapiens	59-63
34215809-6	2021	Considering both economic and environmental benefits, 10 t ha-1 biochar combined with 144 kg ha-1 nitrogen was the best combination to restore crop productivity and soil quality, and to achieve nitrogen decreasing and benefit increasing.	Nitrogen	194-202	Rho GTPase activating protein 45	Homo sapiens	93-97
34447532-1	2021	The dynamic parallel kinetic resolution (DPKR) of an alpha-ferrocenyl cation intermediate under the influence of a chiral conjugate base of a chiral phosphoric acid catalyst has been demonstrated in an SN1 type substitution reaction of a racemic ferrocenyl derivative with a nitrogen nucleophile.	Nitrogen	275-283	solute carrier family 38 member 3	Homo sapiens	202-205
34085593-5	2021	Conversely, absence of a nitrogen source suppresses TORC1 in a manner dependent on GATOR1 as well as the Tsc1-Tsc2 complex, whose mammalian equivalent functions as a growth-factor sensitive TORC1 inhibitor.	Nitrogen	25-33	TSC complex subunit 1	Homo sapiens	105-109
34276694-6	2021	We demonstrated that MMP-9 efficiently cleaved human IL-7 in the exposed loop between the alpha-helices C and D and that this process is delayed by IL-7 N-linked glycosylation.	Nitrogen	153-154	interleukin 7	Homo sapiens	53-57
34276694-6	2021	We demonstrated that MMP-9 efficiently cleaved human IL-7 in the exposed loop between the alpha-helices C and D and that this process is delayed by IL-7 N-linked glycosylation.	Nitrogen	153-154	interleukin 7	Homo sapiens	148-152
34241277-3	2021	Here, we present Raman spectroscopy and x-ray diffraction studies in the H2O-N2 system at high pressures up to 140 GPa.	Nitrogen	77-79	glycophorin A (MNS blood group)	Homo sapiens	115-118
34203347-0	2021	1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors.	Nitrogen	15-23	acetylcholinesterase (Cartwright blood group)	Homo sapiens	91-95
34203347-0	2021	1,3,5-Triazine Nitrogen Mustards with Different Peptide Group as Innovative Candidates for AChE and BACE1 Inhibitors.	Nitrogen	15-23	beta-secretase 1	Homo sapiens	100-105
34203347-1	2021	A series of new analogs of nitrogen mustards (4a-4h) containing the 1,3,5-triazine ring substituted with dipeptide residue were synthesized and evaluated for the inhibition of both acetylcholinesterase (AChE) and beta-secretase (BACE1) enzymes.	Nitrogen	27-35	acetylcholinesterase (Cartwright blood group)	Homo sapiens	181-201
34203347-1	2021	A series of new analogs of nitrogen mustards (4a-4h) containing the 1,3,5-triazine ring substituted with dipeptide residue were synthesized and evaluated for the inhibition of both acetylcholinesterase (AChE) and beta-secretase (BACE1) enzymes.	Nitrogen	27-35	acetylcholinesterase (Cartwright blood group)	Homo sapiens	203-207
34085520-3	2021	At this site, MPO mediates endothelial dysfunction by catalytically consuming nitric oxide (NO) and producing reactive oxidants, hypochlorous acid (HOCl) and the nitrogen dioxide radical ( NO2).	Nitrogen	162-170	myeloperoxidase	Homo sapiens	14-17
34178943-7	2021	We have newly identified systemic site-specific N-glycosylation alterations underlying T2D patients in the complement activation pathways, including decreased levels of N-glycopeptides from C1s, MASP1, and CFP proteins, and increased levels of N-glycopeptides from C2, C4, C4BPA, C4BPB, and CFH.	Nitrogen	48-49	complement C1s	Homo sapiens	190-193
34207447-6	2021	Thus, the objective of this study was to analyse the gene and protein expression of the enzymes NOX-1, NOX-2 and iNOS, which are involved in the production of reactive oxygen and nitrogen species, respectively.	Nitrogen	179-187	nitric oxide synthase 2	Homo sapiens	113-117
34211961-0	2021	Site-Specific N- and O-Glycosylation Analysis of Human Plasma Fibronectin.	Nitrogen	14-15	fibronectin 1	Homo sapiens	62-73
34211961-3	2021	Here, we performed a comprehensive N- and O-glycosylation mapping of human plasma fibronectin and quantified the occurrence of each glycoform in a site-specific manner.	Nitrogen	35-36	fibronectin 1	Homo sapiens	82-93
34129230-1	2021	PURPOSE: To assess the prognostic effect of blood urea nitrogen to serum albumin ratio in patients with Fournier"s gangrene (FG) in a referral center in order to reduce the mortality of FG patients.	Nitrogen	55-63	albumin	Homo sapiens	73-80
34178943-7	2021	We have newly identified systemic site-specific N-glycosylation alterations underlying T2D patients in the complement activation pathways, including decreased levels of N-glycopeptides from C1s, MASP1, and CFP proteins, and increased levels of N-glycopeptides from C2, C4, C4BPA, C4BPB, and CFH.	Nitrogen	48-49	complement factor properdin	Homo sapiens	206-209
34178943-7	2021	We have newly identified systemic site-specific N-glycosylation alterations underlying T2D patients in the complement activation pathways, including decreased levels of N-glycopeptides from C1s, MASP1, and CFP proteins, and increased levels of N-glycopeptides from C2, C4, C4BPA, C4BPB, and CFH.	Nitrogen	48-49	complement component 4 binding protein alpha	Homo sapiens	273-278
33871558-10	2021	Serum triacylglycerol and total adiponectin concentrations were lower, and HOMA-IR was higher, in LEU-PRO+n-3 compared with CON postsupplementation (all P < 0.05).	Nitrogen	106-107	adiponectin, C1Q and collagen domain containing	Homo sapiens	32-43
34097593-8	2022	Molecular docking model displayed a hydrogen bond between Met-769 amide nitrogen and N-1 in pteridine motif of 7m which lay at the ATP binding site of EGFR kinase domain.	Nitrogen	72-80	epidermal growth factor receptor	Homo sapiens	151-155
34099851-3	2021	The expression level of the ATG39 gene is increased in response to ER stress and nitrogen starvation.	Nitrogen	81-89	Atg39p	Saccharomyces cerevisiae S288C	28-33
34099851-6	2021	However, ATG39 expression is still induced by ER stress and nitrogen starvation in the absence of Snf1, suggesting that additional molecules are involved in regulation of ATG39 expression.	Nitrogen	60-68	Atg39p	Saccharomyces cerevisiae S288C	9-14
34099851-6	2021	However, ATG39 expression is still induced by ER stress and nitrogen starvation in the absence of Snf1, suggesting that additional molecules are involved in regulation of ATG39 expression.	Nitrogen	60-68	Atg39p	Saccharomyces cerevisiae S288C	171-176
34088317-9	2021	The levels of IL-6 and TNF-alpha correlated with the levels of creatinine and urea nitrogen, and were also higher in ARDS patients with acute kidney injury (AKI).	Nitrogen	83-91	interleukin 6	Homo sapiens	14-18
34088317-9	2021	The levels of IL-6 and TNF-alpha correlated with the levels of creatinine and urea nitrogen, and were also higher in ARDS patients with acute kidney injury (AKI).	Nitrogen	83-91	tumor necrosis factor	Homo sapiens	23-32
34195594-2	2021	As such, the Nrf2 pathway is critical in guarding the cell from the harmful effects of excessive reactive oxygen species/reactive nitrogen species (ROS/RNS) and in maintaining cellular redox balance.	Nitrogen	130-138	NFE2 like bZIP transcription factor 2	Homo sapiens	13-17
34152451-1	2021	Ure2 regulates nitrogen catabolite repression in Saccharomyces cerevisiae.	Nitrogen	15-23	glutathione peroxidase	Saccharomyces cerevisiae S288C	0-4
34152451-2	2021	Deletion of URE2 induces a physiological state mimicking the nitrogen starvation and autophagic responses.	Nitrogen	61-69	glutathione peroxidase	Saccharomyces cerevisiae S288C	12-16
34152451-10	2021	The induction of a nitrogen starvation-like state and increase in lipid production in nitrogen-rich conditions suggest that URE2 may be a promising target for metabolic engineering in S. cerevisiae and other yeasts for the production of lipids and lipid-derived compounds.	Nitrogen	19-27	glutathione peroxidase	Saccharomyces cerevisiae S288C	124-128
34152451-10	2021	The induction of a nitrogen starvation-like state and increase in lipid production in nitrogen-rich conditions suggest that URE2 may be a promising target for metabolic engineering in S. cerevisiae and other yeasts for the production of lipids and lipid-derived compounds.	Nitrogen	86-94	glutathione peroxidase	Saccharomyces cerevisiae S288C	124-128
34094685-4	2021	Here we show that the immunosuppression activity of Siglec15 is largely modulated by N-glycosylation.	Nitrogen	85-86	sialic acid binding Ig like lectin 15	Homo sapiens	52-60
34094685-9	2021	Interestingly, removal of N-glycosylation enhances the detection of Siglec15, which may be employed in the prediction of immunotherapy response.	Nitrogen	26-27	sialic acid binding Ig like lectin 15	Homo sapiens	68-76
34066426-5	2021	A significantly higher soil NH4-N and NO3-N concentrations were detected in the topsoil depth than the two lower soil depths (15-30 and 30-45 cm) indicating lesser nutrient leaching as trees received moderate (224 kg ha-1) N rate.	Nitrogen	223-224	Rho GTPase activating protein 45	Homo sapiens	217-221
34567179-2	2021	Based on our previous in-silico studies, two sites were selected in the N-terminal gamma-carboxy glutamic acid-rich (Gla) domain of the human clotting factor IX (hFIX) to add new N-glycosylation sites.	Nitrogen	179-180	coagulation factor IX	Homo sapiens	162-166
34567179-3	2021	Site-directed mutagenesis was employed to conduct K22N and R37N substitutions and introduce new N-glycosylation sites in the mature hFIX.	Nitrogen	96-97	coagulation factor IX	Homo sapiens	132-136
34168784-0	2021	Facilitated inversion complicates the stereodynamics of an SN2 reaction at nitrogen center.	Nitrogen	75-83	solute carrier family 38 member 5	Homo sapiens	59-62
34168784-2	2021	Reaction dynamics simulations on a newly developed high-level ab initio analytical potential energy surface for the F- + NH2Cl nitrogen-centered SN2 and proton-transfer reactions reveal a hydrogen-bond-formation-induced multiple-inversion mechanism undermining the stereospecificity of the N-centered SN2 channel.	Nitrogen	127-135	solute carrier family 38 member 5	Homo sapiens	145-148
34168784-2	2021	Reaction dynamics simulations on a newly developed high-level ab initio analytical potential energy surface for the F- + NH2Cl nitrogen-centered SN2 and proton-transfer reactions reveal a hydrogen-bond-formation-induced multiple-inversion mechanism undermining the stereospecificity of the N-centered SN2 channel.	Nitrogen	127-135	solute carrier family 38 member 5	Homo sapiens	301-304
34149831-3	2021	Methods: Herein, we combined the electrophysiological approach with molecular mutations and biochemical manipulation to investigate the function roles of N-glycosylation in beta1 subunits.	Nitrogen	154-155	BCL2 related protein A1	Homo sapiens	173-178
34064734-2	2021	In this work, a cost-effective synthesis strategy for nitrogen and oxygen co-doped porous carbon (NOC) from petroleum sludge waste was developed.	Nitrogen	54-62	nocturnin	Homo sapiens	98-101
35523353-3	2022	Fe(III) was anchored in nitrogen-coordinated pots (Fe-Nx) in the sp2-hybridized carbon network, and graphitic-N could synergistically boost the catalysis.	Nitrogen	24-32	Sp2 transcription factor	Homo sapiens	65-68
34955553-4	2021	Due to the thiol group of Cys34, albumin can serve as a trap for reactive oxygen and nitrogen species, thus participating in redox processes.	Nitrogen	85-93	albumin	Homo sapiens	33-40
34611370-8	2021	The degradation of SMP in UV/Co(II)/PMS system was accomplished mainly by hydroxylation of the aromatic ring, extrusion of SO2, oxidation of NH2 group, and N - S bond cleavage.	Nitrogen	156-157	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	29-35
35525348-3	2022	Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process.	Nitrogen	121-122	NBL1, DAN family BMP antagonist	Homo sapiens	116-119
35525348-3	2022	Although some studies have used nitrate isotopic composition (delta15N-NO3- and delta18O-NO3-) to identify nitrate (NO3--N) in urban storm runoff, the relatively low frequency of collecting samples in surface runoff within a single functional area hinders the understanding of spatial variations and dynamic process of NO3--N sources over the runoff process.	Nitrogen	324-325	NBL1, DAN family BMP antagonist	Homo sapiens	116-119
35525348-4	2022	This study investigated the nitrogen (N) concentrations and analyzed dynamic changes of NO3--N sources in surface runoff in different urban functional areas, drainage pipeline runoff, and channels during the complete runoff process in Wuxi, east China.	Nitrogen	93-94	NBL1, DAN family BMP antagonist	Homo sapiens	88-91
35525348-6	2022	Information of delta15N-NO3- and delta18O-NO3- suggested that the main NO3--N source varied between runoff stages.	Nitrogen	76-77	NBL1, DAN family BMP antagonist	Homo sapiens	71-74
35525348-7	2022	NO3--N contribution from atmospheric deposition decreased in the order: surface runoff (57%) > residential pipeline runoff (25%) > channels (14%), while the opposite trend was observed for the contributions from sewage, increasing from 10% to 26% to 39%.	Nitrogen	5-6	NBL1, DAN family BMP antagonist	Homo sapiens	0-3
34495528-6	2021	Subsequently, the N-glycosylated nascent proteins enter the folding step, in which N-glycans contribute largely to attaining the correct protein fold by recruiting the lectin-like chaperones, calnexin, and calreticulin.	Nitrogen	18-19	calreticulin	Homo sapiens	206-218
34756244-1	2021	Calreticulin (CALR) is a chaperone present in the endoplasmic reticulum, which is involved in the quality control of N-glycosylated proteins and storage of calcium ions.	Nitrogen	117-118	calreticulin	Homo sapiens	0-12
34756244-1	2021	Calreticulin (CALR) is a chaperone present in the endoplasmic reticulum, which is involved in the quality control of N-glycosylated proteins and storage of calcium ions.	Nitrogen	117-118	calreticulin	Homo sapiens	14-18
34720208-1	2021	Background: For more than a century, crop N nutrition research has primarily focused on inorganic N (IN) dynamics, building the traditional model that agricultural plants predominantly take up N in the form of NO3 - and NH4 +.	Nitrogen	98-99	NBL1, DAN family BMP antagonist	Homo sapiens	210-213
34720208-1	2021	Background: For more than a century, crop N nutrition research has primarily focused on inorganic N (IN) dynamics, building the traditional model that agricultural plants predominantly take up N in the form of NO3 - and NH4 +.	Nitrogen	193-194	NBL1, DAN family BMP antagonist	Homo sapiens	210-213
35461117-3	2022	The Abeta was rapidly recognized using the fluorescent emitter-nitrogen-doped carbon nanodots (N-CDs) under the regulation of BP nanosheets, while the N-CDs alone cannot recognize Abeta without the introduction of BP.	Nitrogen	63-71	amyloid beta precursor protein	Homo sapiens	4-9
35487360-11	2022	The metal ions with weak hydrolysis constants and strong polarization forces could readily interact with N-containing histidine and S-containing cysteine of p53 DBD, which resulted in high Ka values.	Nitrogen	105-106	tumor protein p53	Homo sapiens	157-160
35246853-6	2022	Moreover, VCAM-1 was positively correlated with d-dimer (R = 0.544, p < 0.001); tPA was positively correlated with d-dimer (R = 0.800, p < 0.001) and blood urea nitrogen (R = 0.638, p < 0.001).	Nitrogen	161-169	plasminogen activator, tissue type	Homo sapiens	80-83
35427795-6	2022	The conversion of free fatty acids into triglycerides in the female pparg mutants was hampered by reduced esterification efficiency, thus induced lipotoxicity, as evidenced by high oxidative stress and damaged health in these mutants, which led to reduced resistance to cold, heat and ammonia nitrogen stresses.	Nitrogen	293-301	peroxisome proliferator-activated receptor gamma	Danio rerio	68-73
35598422-5	2022	The studies on the interaction with two proteins, lysozyme (Lyz) chosen as a representative model of a small protein, and human serum albumin (HSA) show that two types of binding are possible: a non-covalent binding through the accessible residues on protein surface with (VIVO(L1-3)(LNN)) keeping its octahedral structure, and a covalent binding upon the replacement of water in (VIVO(L1-3)(H2O)) with His-N donors to form VIVO(L1-3)(HSA).	Nitrogen	407-408	lysozyme	Homo sapiens	50-58
35598422-5	2022	The studies on the interaction with two proteins, lysozyme (Lyz) chosen as a representative model of a small protein, and human serum albumin (HSA) show that two types of binding are possible: a non-covalent binding through the accessible residues on protein surface with (VIVO(L1-3)(LNN)) keeping its octahedral structure, and a covalent binding upon the replacement of water in (VIVO(L1-3)(H2O)) with His-N donors to form VIVO(L1-3)(HSA).	Nitrogen	407-408	lysozyme	Homo sapiens	60-63
35598422-5	2022	The studies on the interaction with two proteins, lysozyme (Lyz) chosen as a representative model of a small protein, and human serum albumin (HSA) show that two types of binding are possible: a non-covalent binding through the accessible residues on protein surface with (VIVO(L1-3)(LNN)) keeping its octahedral structure, and a covalent binding upon the replacement of water in (VIVO(L1-3)(H2O)) with His-N donors to form VIVO(L1-3)(HSA).	Nitrogen	407-408	albumin	Homo sapiens	128-141
35491865-0	2022	LINC00173 Promotes Wilms" Tumor Progression Through MGAT1-mediated MUC3A N-glycosylation.	Nitrogen	73-74	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	52-57
35271927-7	2022	Low N removal rates, especially near the project inflow where temperatures will be coldest will favor transport of NO3- further into Barataria Basin where eutrophic conditions could become expressed.	Nitrogen	4-5	NBL1, DAN family BMP antagonist	Homo sapiens	115-118
35192819-0	2022	Effect of the organic loading rate on the PHA-storing microbiome in sequencing batch reactors operated with uncoupled carbon and nitrogen feeding.	Nitrogen	129-137	lamin B receptor	Homo sapiens	42-45
35192819-2	2022	Under a feast and famine regime, an uncoupled carbon (C) and nitrogen (N)-feeding strategy may be adopted by dosing the C-source at the beginning of the feast and the N-source at the beginning of the famine in order to stimulate a PHA storage response and microbial growth.	Nitrogen	61-69	lamin B receptor	Homo sapiens	231-234
35192819-2	2022	Under a feast and famine regime, an uncoupled carbon (C) and nitrogen (N)-feeding strategy may be adopted by dosing the C-source at the beginning of the feast and the N-source at the beginning of the famine in order to stimulate a PHA storage response and microbial growth.	Nitrogen	71-72	lamin B receptor	Homo sapiens	231-234
35192819-2	2022	Under a feast and famine regime, an uncoupled carbon (C) and nitrogen (N)-feeding strategy may be adopted by dosing the C-source at the beginning of the feast and the N-source at the beginning of the famine in order to stimulate a PHA storage response and microbial growth.	Nitrogen	167-168	lamin B receptor	Homo sapiens	231-234
35192819-4	2022	To fill the gap, this study investigated the effect of the OLR on the selection of PHA-accumulating microorganisms in a sequencing batch reactor (SBR) operated with an uncoupled C and N feeding strategy.	Nitrogen	184-185	lamin B receptor	Homo sapiens	83-86
35491865-11	2022	Meanwhile, MGAT1 was verified to stabilize MUC3A protein by inducing N-glycosylation.	Nitrogen	69-70	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	11-16
35192834-6	2022	We found that the activities of BG, NAG, and AP were predominately dependent on plant N contents, while the soil LAP activity was tightly related to soil recalcitrant C and N contents.	Nitrogen	86-87	N-acetyl-alpha-glucosaminidase	Homo sapiens	36-39
35491865-12	2022	In summary, our study first discovered that LINC00173 promoted WT progression through MGAT1-mediated MUC3A N-glycosylation, giving new clues to further understanding the mechanism underlying WT progression.	Nitrogen	107-108	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	86-91
35605989-4	2022	The increased chemoselectivity for sulphur-alkylation products was ascribed to CO2 as a temporary and traceless protecting group for nitrogen nucleophiles, while CO2 efficiently provide higher conversion and selectivity sulphur nucleophiles on peptides and human serum albumin (HSA) with various electrophiles.	Nitrogen	133-141	albumin	Homo sapiens	263-276
35460603-4	2022	Here, we report that DNA virus induces a reactive nitrogen species (RNS)-dependent DNA damage and activates DNA-dependent protein kinase (DNA-PK).	Nitrogen	50-58	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	108-136
35460603-4	2022	Here, we report that DNA virus induces a reactive nitrogen species (RNS)-dependent DNA damage and activates DNA-dependent protein kinase (DNA-PK).	Nitrogen	50-58	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	138-144
35192852-4	2022	Based on the analysis of transcriptomics and nitrogen metabolites, this study showed that 400 mg L-1 GO exposure downregulated most of the genes encoding nitrogen-assimilating enzymes, including nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	154-162	glutamate-ammonia ligase	Homo sapiens	219-239
35192852-4	2022	Based on the analysis of transcriptomics and nitrogen metabolites, this study showed that 400 mg L-1 GO exposure downregulated most of the genes encoding nitrogen-assimilating enzymes, including nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	154-162	glutamate-ammonia ligase	Homo sapiens	241-243
35019185-6	2022	Modifications to the standard CLM5.0 at Hubbard Brook indicate that a simultaneous increase in the competitiveness of nitrifying microbes for NH4 + and reduction in the competitiveness of denitrifying bacteria for NO3 - are needed to bring soil N flux ratios into better agreement with observations.	Nitrogen	245-246	NBL1, DAN family BMP antagonist	Homo sapiens	214-217
35019177-6	2022	Both models dramatically underestimate the immobilization of NO3 - by soil bacteria compared to literature values and predict dominance of plant uptake by a single form of mineral nitrogen (NO3 - for ELM, with regional exceptions, and NH4 + for CLM5.0).	Nitrogen	180-188	NBL1, DAN family BMP antagonist	Homo sapiens	61-64
35019177-6	2022	Both models dramatically underestimate the immobilization of NO3 - by soil bacteria compared to literature values and predict dominance of plant uptake by a single form of mineral nitrogen (NO3 - for ELM, with regional exceptions, and NH4 + for CLM5.0).	Nitrogen	180-188	NBL1, DAN family BMP antagonist	Homo sapiens	190-193
35227848-9	2022	This study suggests reducing anthropogenic nitrogen discharge (e.g., leaching agents and fertilizer inputs) as the primary means of NO3- pollution control with biogeochemical processes (e.g., denitrification) to further reduce its pollution.	Nitrogen	43-51	NBL1, DAN family BMP antagonist	Homo sapiens	132-135
35381575-5	2022	Hepatocytes from the human donor genotyped as CYP3A5*3/*3 (poor expressers) showed significantly lower T-1032 N-oxidation rates than those from donors harboring CYP3A5*1.	Nitrogen	110-111	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	46-52
35381575-8	2022	These results suggest that polymorphic CYP3A5-dependent T-1032 N-oxidation was observed in humanized liver mice in vitro and in vivo.	Nitrogen	63-64	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	39-45
35483145-0	2022	In Silico simulation of Cytochrome P450-Mediated metabolism of aromatic amines: A case study of N-Hydroxylation.	Nitrogen	96-97	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	24-39
35227848-1	2022	Nitrate (NO3-) pollution in water bodies has received widespread attention, but studies on nitrogen transformation and pollution risk assessment are still limited, especially in rare earth mining areas.	Nitrogen	91-99	NBL1, DAN family BMP antagonist	Homo sapiens	9-12
35227848-6	2022	The high variability of delta15N-NO3- (from -6.43 to 17.09%) and delta18O-NO3- (from -7.91 to 22.79%) showed that NO3- was influenced by multiple nitrogen sources and transformation processes.	Nitrogen	146-154	NBL1, DAN family BMP antagonist	Homo sapiens	114-117
35468314-1	2022	The location of the phloem deep inside the plant, the high hydrostatic pressure in the phloem, and the composition of phloem sap, which is rich in sugar with a high C:N ratio, allows phloem sap feeding insects to occupy a unique ecological niche.	Nitrogen	167-168	SH2 domain containing 1A	Homo sapiens	125-128
35272941-1	2022	INTRODUCTION: Previous studies have revealed that blood urea nitrogen-to-serum albumin ratio (BUN/ALB) is one of major risk factors of mortality in pneumonia.	Nitrogen	61-69	albumin	Homo sapiens	79-86
35272941-1	2022	INTRODUCTION: Previous studies have revealed that blood urea nitrogen-to-serum albumin ratio (BUN/ALB) is one of major risk factors of mortality in pneumonia.	Nitrogen	61-69	albumin	Homo sapiens	98-101
35150690-8	2022	In the wet season, sewage (~87.5%), soil organic N (6.7%), and chemical fertilizer (5.8%) were the main sources of NO3- in the Kabul aquifer.	Nitrogen	49-50	NBL1, DAN family BMP antagonist	Homo sapiens	115-118
35510762-6	2022	The experimental results demonstrated that 217 N-glycosylation sites were identified in 283 N-glycopeptides, corresponding to 95 glycoproteins identified from 10 muL human serum by the nano-LC-MS/MS analysis, revealing the great potential of the novel ZIF-8/SAP hydrogel for glycopeptide enrichment and glycoproteomic research.	Nitrogen	47-48	SH2 domain containing 1A	Homo sapiens	258-261
35561157-9	2022	DOC and NO3 - were negatively related before and after restoration suggesting C limitation of N transformations.	Nitrogen	94-95	NBL1, DAN family BMP antagonist	Homo sapiens	8-11
35561157-12	2022	Modeled NO3 - flux decreased post restoration over time but the rate of decrease was reduced likely due to failure of restoration features that facilitated N transformations.	Nitrogen	156-157	NBL1, DAN family BMP antagonist	Homo sapiens	8-11
35561157-13	2022	Groundwater NO3 - concentrations varied among stream features suggesting that some engineered features may be functionally better at creating optimal conditions for N retention.	Nitrogen	165-166	NBL1, DAN family BMP antagonist	Homo sapiens	12-15
35151728-9	2022	The optimum dose of N for maize grown with mulching ranged between 150 kg ha-1 and 200 kg ha-1 and offers the best balance between higher yield and lower emissions.	Nitrogen	20-21	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	74-94
35609700-6	2022	The extreme BB emissions lead to significant contributions to the total N deposition for different ecosystems in California, with an average August - October 2020 relative increase of ~78% (from 7.1 to 12.6 kg ha-1 year-1) in deposition rate to major vegetation types (mixed forests + grasslands/shrublands/savanna) compared to the GMU-WFS simulations without BB emissions.	Nitrogen	72-73	Rho GTPase activating protein 45	Homo sapiens	210-214
35604219-5	2022	Here, we constructed a recombinant baculovirus (BacMam) expressing consensus porcine interferon alpha (IFN-alpha) that has three additional N-glycosylation sites driven by a cytomegalovirus immediate early (CMV-IE) promoter (Bac-Con3N IFN-alpha) for protein expression in mammalian cells.	Nitrogen	140-141	interferon alpha 1	Homo sapiens	103-112
35604219-5	2022	Here, we constructed a recombinant baculovirus (BacMam) expressing consensus porcine interferon alpha (IFN-alpha) that has three additional N-glycosylation sites driven by a cytomegalovirus immediate early (CMV-IE) promoter (Bac-Con3N IFN-alpha) for protein expression in mammalian cells.	Nitrogen	140-141	interferon alpha 1	Homo sapiens	235-244
35609700-7	2022	For mixed forest types only, the average N deposition rate increases (from 6.2 to 16.9 kg ha-1 year-1) are even larger at ~173%.	Nitrogen	41-42	Rho GTPase activating protein 45	Homo sapiens	90-94
35503527-4	2022	Under N2 atmosphere at room temperature, tBu-TPIRs form SpI with a spiro carbon and a novel HABI isomer tBu-1,4"-HABI, whose bonding pattern is different from that of the original unsubstituted HABI (1,2"-HABI).	Nitrogen	6-8	chromogranin A	Homo sapiens	56-59
35503527-5	2022	The results of 1H NMR spectroscopy, EPR measurements, and DFT calculations revealed that SpI is generated via three steps: (1) intramolecular hydrogen transfer from the tBu group to the nitrogen atom of the imidazole ring, (2) intramolecular cyclization of alkyl radicals, and (3) intermolecular hydrogen transfer with another tBu-TPIR.	Nitrogen	186-194	chromogranin A	Homo sapiens	89-92
35583079-3	2022	Fine X-ray photoelectron spectroscopy and Fourier-transform infrared spectroscopy analyses reported calcium-dependent shifts of the binding energy in nitrogen and oxygen involved groups and wavenumbers in the amide I and II bands of the adsorbent fibrinogen, demonstrating that locally delivered calcium can react with the carboxy-terminal regions of the Aalpha chains and influence their interaction with the N-termini of the Bbeta chains in fibrinogen.	Nitrogen	150-158	fibrinogen beta chain	Homo sapiens	247-257
35617789-8	2022	The coupled denitrification and anammox may play significant roles in N removal, and the availability of electronic acceptors (i.e., NO2- and NO3-) strongly influenced the N loss in lake sediments.	Nitrogen	172-173	NBL1, DAN family BMP antagonist	Homo sapiens	142-145
35617789-9	2022	Further path analysis indicated that NO2-, NO3- and some N-related enzymes were the key factors affecting microbial N removal in lake sediments.	Nitrogen	116-117	NBL1, DAN family BMP antagonist	Homo sapiens	43-46
35586945-6	2022	Moreover, distinct types of N-glycans on specific N-glycosylation sites regulate DMA-1/LRR-TM receptor function, which, together with three other extracellular proteins, forms the Menorin adhesion complex.	Nitrogen	50-51	LRRCT domain-containing protein	Caenorhabditis elegans	81-86
35583079-3	2022	Fine X-ray photoelectron spectroscopy and Fourier-transform infrared spectroscopy analyses reported calcium-dependent shifts of the binding energy in nitrogen and oxygen involved groups and wavenumbers in the amide I and II bands of the adsorbent fibrinogen, demonstrating that locally delivered calcium can react with the carboxy-terminal regions of the Aalpha chains and influence their interaction with the N-termini of the Bbeta chains in fibrinogen.	Nitrogen	150-158	fibrinogen beta chain	Homo sapiens	443-453
35585790-2	2022	In plants, nutrients are remobilized and reallocated between shoots and roots under low nutrient conditions, and nitrogen and nitrogen-related nutrients (e.g., amino acids) are key upstream signals leading to TOR activation in shoots under low nutrient conditions.	Nitrogen	113-121	target of rapamycin	Arabidopsis thaliana	209-212
35579574-7	2022	Moreover, in cisplatin- or ischemia/reperfusion (I/R) induced AKI mouse model, detection of creatinine and urea nitrogen in blood showed that Cpd-2 improved kidney function.	Nitrogen	112-120	Ca2+-dependent activator protein for secretion 2	Mus musculus	142-147
35585790-2	2022	In plants, nutrients are remobilized and reallocated between shoots and roots under low nutrient conditions, and nitrogen and nitrogen-related nutrients (e.g., amino acids) are key upstream signals leading to TOR activation in shoots under low nutrient conditions.	Nitrogen	126-134	target of rapamycin	Arabidopsis thaliana	209-212
35585790-3	2022	However, how these forms of nitrogen can be sensed to activate TOR in plants is still poorly understood.	Nitrogen	28-36	target of rapamycin	Arabidopsis thaliana	63-66
35585790-4	2022	Here, we found that the plant receptor kinase FERONIA (FER) interacts with the TOR pathway to regulate nutrient (nitrogen and amino acid) signaling under low nutrient conditions, and exerts similar metabolic effects in response to nitrogen-deficiency in Arabidopsis.	Nitrogen	113-121	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	46-53
35585790-4	2022	Here, we found that the plant receptor kinase FERONIA (FER) interacts with the TOR pathway to regulate nutrient (nitrogen and amino acid) signaling under low nutrient conditions, and exerts similar metabolic effects in response to nitrogen-deficiency in Arabidopsis.	Nitrogen	113-121	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	55-58
35585790-4	2022	Here, we found that the plant receptor kinase FERONIA (FER) interacts with the TOR pathway to regulate nutrient (nitrogen and amino acid) signaling under low nutrient conditions, and exerts similar metabolic effects in response to nitrogen-deficiency in Arabidopsis.	Nitrogen	113-121	target of rapamycin	Arabidopsis thaliana	79-82
35585790-4	2022	Here, we found that the plant receptor kinase FERONIA (FER) interacts with the TOR pathway to regulate nutrient (nitrogen and amino acid) signaling under low nutrient conditions, and exerts similar metabolic effects in response to nitrogen-deficiency in Arabidopsis.	Nitrogen	231-239	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	46-53
35585790-4	2022	Here, we found that the plant receptor kinase FERONIA (FER) interacts with the TOR pathway to regulate nutrient (nitrogen and amino acid) signaling under low nutrient conditions, and exerts similar metabolic effects in response to nitrogen-deficiency in Arabidopsis.	Nitrogen	231-239	Malectin/receptor-like protein kinase family protein	Arabidopsis thaliana	55-58
35285636-0	2022	Nitrogen-Centered Radicals in Functionalization of sp2 Systems: Generation, Reactivity, and Applications in Synthesis.	Nitrogen	0-8	Sp2 transcription factor	Homo sapiens	51-54
35552412-3	2022	We initially observed altered leaf to seed ratios, faster senescence progression, altered leaf nitrogen recovery after transient nitrogen removal and ultimately enhanced nitrogen remobilization from the leaves in two methylation mutants (ros1 and the triple dmr1/2 cmt3 knockout).	Nitrogen	170-178	demeter-like 1	Arabidopsis thaliana	238-242
35500109-3	2022	Here, we proposed a simple strategy for the preparation of a heterogeneous photocatalyst suitable for photo induced atom transfer radical polymerization (photoATRP) under full spectrum (from UV/vis light to NIR), by combining pyridine nitrogen doped carbon dots (N-CDs) and upconversion nanoparticles (UCNPs).	Nitrogen	235-243	NOC2 like nucleolar associated transcriptional repressor	Homo sapiens	207-210
35578571-13	2022	CONCLUSION: Biological activity of IL-6/gp130 axis promoted N-inv in murine model and was upregulated in PDAC patients with severe N-inv.	Nitrogen	131-132	interleukin 6	Mus musculus	35-39
35578571-13	2022	CONCLUSION: Biological activity of IL-6/gp130 axis promoted N-inv in murine model and was upregulated in PDAC patients with severe N-inv.	Nitrogen	131-132	interleukin 6 signal transducer	Mus musculus	40-45
35594589-0	2022	Using sp2 N atom anchoring effect to prepare ultrafine vanadium nitride particles on porous nitrogen-doped carbon as cathode for lithium-sulfur battery.	Nitrogen	10-11	Sp2 transcription factor	Homo sapiens	6-9
35594589-4	2022	4 nm (VN/M/NC) are successfully grown on the surface of nitrogen-doped three-dimensional carbon using sp2 nitrogen atoms, resulting from melamine pyrolysis in the presence of ammonium metavanadate, as anchor points to lock vanadium atoms in the VN/M/NC material.	Nitrogen	56-64	Sp2 transcription factor	Homo sapiens	102-105
35594589-4	2022	4 nm (VN/M/NC) are successfully grown on the surface of nitrogen-doped three-dimensional carbon using sp2 nitrogen atoms, resulting from melamine pyrolysis in the presence of ammonium metavanadate, as anchor points to lock vanadium atoms in the VN/M/NC material.	Nitrogen	106-114	Sp2 transcription factor	Homo sapiens	102-105
35482287-0	2022	Syntheses, rearrangements, and structural analyses of unsaturated nitrogen donor ligands derived from diphenyldiazomethane and the chiral rhenium Lewis acid ((eta5-C5H5)Re(NO)(PPh3)).	Nitrogen	66-74	caveolin 1	Homo sapiens	176-180
35626629-1	2022	N-terminal nucleophile (Ntn)-hydrolases catalyze the cleavage of amide bonds in a variety of macromolecules, including the peptide bond in proteins, the amide bond in N-linked protein glycosylation, and the amide bond linking a fatty acid to sphingosine in complex sphingolipids.	Nitrogen	167-168	neurotensin	Homo sapiens	24-27
35333306-0	2022	The Mnn10/Anp1-dependent N-linked outer chain glycan is dispensable for Candida albicans cell wall integrity.	Nitrogen	25-26	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	4-9
35477280-1	2022	A new porous metal-organic framework, (Co (oba) (bpdh)) (DMF) (TMU-63), containing accessible nitrogen-rich diazahexadiene groups was successfully prepared with the solvothermal assembly of 5-bis(4-pyridyl)-3,4-diaza-2,4-hexadiene (4-bpdh), 4,4"-oxybis(benzoic) acid (oba), and Co(II) ions.	Nitrogen	94-102	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	278-284
35572169-1	2022	Background: Considering the role of higher blood urea nitrogen and lower serum albumin (SA) levels in deceased coronavirus disease 2019 (COVID-19) patients, an increased blood urea nitrogen to SA (B/A) ratio may help to determine those at higher risk of critical illness.	Nitrogen	181-189	albumin	Homo sapiens	73-86
35548710-4	2022	We found that the h-mIL-6R and the commercial IL-6R mAb Tocilizumab significantly improved the survival rate, reduced the levels of TNF-alpha, IL-6, IL-1beta, IFN-gamma, transaminases and blood urea nitrogen of LPS-induced SIRS mice.	Nitrogen	199-207	interleukin 6 receptor, alpha	Mus musculus	20-26
35150821-5	2022	Functional studies verified that the endocytosis-related genes CAP1 and END3 significantly increased the utilization of multiple non-preferred amino acids and reduced the accumulation of the harmful nitrogen metabolite precursor urea by regulating amino acid transporters and TOR pathway.	Nitrogen	199-207	End3p	Saccharomyces cerevisiae S288C	72-76
35476416-5	2022	Interestingly, through the downregulation of enhanced expression of glutathione peroxidase, superoxide dismutase, and catalase as well as inflammatory responses, N-CNRs reverse pancreatic dysfunction and normalize the secretory functions of pancreatic cells.	Nitrogen	162-164	catalase	Homo sapiens	118-126
35416037-0	2022	Cryptic Sulfur and Oxygen Cycling Potentially Reduces N2O-Driven Greenhouse Warming: Underlying Revision Need of the Nitrogen Cycle.	Nitrogen	117-125	cripto, FRL-1, cryptic family 1	Homo sapiens	0-7
35442647-3	2022	These N vacancies enhanced the electron distribution of the Co 3d orbital and lowered the energy barrier to cleave the O-O bond of PMS in the Co(II)-PMS complex, achieving the modulation of major active species from 1O2 to Co(IV) O.	Nitrogen	6-7	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	142-148
35499352-8	2022	10 N-glycosylation sites were predicted, and positions N44 and N51 were detected in most GP5 sequences (n = 1,801(93.3%)).	Nitrogen	3-4	glycoprotein V platelet	Homo sapiens	89-92
35499352-5	2022	N-glycosylation and the global and local selection pressure in the putative GP5 encoded by ORF5 were estimated.	Nitrogen	0-1	glycoprotein V platelet	Homo sapiens	76-79
35077598-9	2022	As a result, N2 exhibited the lowest electronegative value and highest binding energy when docked with anti-inflammatory and anti-oxidant proteins CAT, COX, GP, IL-1, and MPO.	Nitrogen	13-15	myeloid-specific peroxidase	Danio rerio	171-174
35491506-2	2022	Our previous study revealed that HISTONE DEACETYLASE 9 (HDA9) interacts with ELONGATED HYPOCOTYL 5 (HY5) and is involved in regulating plant autophagy in response to the light-to-dark transition and nitrogen starvation.	Nitrogen	199-207	histone deacetylase 9	Arabidopsis thaliana	33-54
35050478-6	2022	Soil aG, betaG, CBH, and ACP activity increase significantly (p < 0.05) under elevated temperature + N relative to elevated temperature alone.	Nitrogen	101-102	floral homeotic protein AGAMOUS-like	Camellia sinensis	5-7
35050478-6	2022	Soil aG, betaG, CBH, and ACP activity increase significantly (p < 0.05) under elevated temperature + N relative to elevated temperature alone.	Nitrogen	101-102	floral homeotic protein AGAMOUS-like	Camellia sinensis	9-14
35157877-7	2022	The amoA-AOA gene abundance, NAG activity, and total carbon (C) content were the main predictors of total N and mineral N accumulated leakage.	Nitrogen	106-107	N-acetyl-alpha-glucosaminidase	Homo sapiens	29-32
35157877-7	2022	The amoA-AOA gene abundance, NAG activity, and total carbon (C) content were the main predictors of total N and mineral N accumulated leakage.	Nitrogen	120-121	N-acetyl-alpha-glucosaminidase	Homo sapiens	29-32
35491506-2	2022	Our previous study revealed that HISTONE DEACETYLASE 9 (HDA9) interacts with ELONGATED HYPOCOTYL 5 (HY5) and is involved in regulating plant autophagy in response to the light-to-dark transition and nitrogen starvation.	Nitrogen	199-207	histone deacetylase 9	Arabidopsis thaliana	56-60
35491506-2	2022	Our previous study revealed that HISTONE DEACETYLASE 9 (HDA9) interacts with ELONGATED HYPOCOTYL 5 (HY5) and is involved in regulating plant autophagy in response to the light-to-dark transition and nitrogen starvation.	Nitrogen	199-207	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	100-103
35484284-7	2022	We identified 22 upregulated and 1 down-regulated N-glycosylated peptides in the OA group compared to the NC group, while only fibronectin 1 (FN1) at position N1007, cartilage intermediate layer protein 1 (CILP) at N346, and collagen type VI alpha 1 chain (COL6A1) at N804, were also identified in the DM-OA group.	Nitrogen	50-51	fibronectin 1	Homo sapiens	127-140
35042029-2	2022	Herein, we reported a dual-ion MALDI matrix of yolk-shell Ni/NiO nanoparticles anchored on nitrogen-doped graphene (Ni/NiO/N-Gr) to enhance MALDI performance.	Nitrogen	91-99	reticulon 4 receptor	Mus musculus	123-127
35566244-5	2022	The data obtained from the EDX analysis of the novel cross-linked copolymers confirmed the functionalization with aminobenzoic groups through the presence and content of nitrogen, as follows: PAB1: N% = 0.47; PAB2: N% = 0.85; and PAB3: N% = 1.30.	Nitrogen	170-178	poly(A) binding protein cytoplasmic 1 pseudogene 10	Homo sapiens	192-196
35299066-2	2022	Besides providing nitrogen substrates and carbon framework for energy homeostasis and transamination, BCAA also function as signaling molecules in the regulation of glucose, lipid, and protein synthesis via protein kinase B and as a mechanistic target of the rapamycin (AKT-mTOR) signaling pathway that is important for muscle accretion.	Nitrogen	18-26	AT-rich interaction domain 4B	Homo sapiens	102-106
35299066-8	2022	Additionally, several studies focused on the effects of BCAA in low protein diets as a strategy to reduce nitrogen excretion.	Nitrogen	106-114	AT-rich interaction domain 4B	Homo sapiens	56-60
35484284-9	2022	The differentially expressed N-glycosylated proteins between the OA and DM-OA groups were mainly located extracellularly and enriched in the KEGG pathways involving PI3K/Akt signaling, focal adhesion, and ECM-receptor interaction.	Nitrogen	29-30	AKT serine/threonine kinase 1	Homo sapiens	170-173
35484284-7	2022	We identified 22 upregulated and 1 down-regulated N-glycosylated peptides in the OA group compared to the NC group, while only fibronectin 1 (FN1) at position N1007, cartilage intermediate layer protein 1 (CILP) at N346, and collagen type VI alpha 1 chain (COL6A1) at N804, were also identified in the DM-OA group.	Nitrogen	50-51	fibronectin 1	Homo sapiens	142-145
35460591-5	2022	In addition, by using precise delivery of solutes into the xylem stream of Populus trees in their natural environment, we found that delay of autumn senescence was dependent on the form of N administered: inorganic N (NO3 - ) delayed senescence but amino acids (Arg, Glu, Gln, and Leu) did not.	Nitrogen	189-190	NBL1, DAN family BMP antagonist	Homo sapiens	218-221
35573732-0	2022	Nascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2.	Nitrogen	35-36	protein phosphatase 1 regulatory inhibitor subunit 1A	Homo sapiens	58-69
35478427-0	2022	Saving the Energy Loss in Lithium-Mediated Nitrogen Fixation by Using a Highly Reactive Li3 N Intermediate for C-N Coupling Reactions.	Nitrogen	43-51	cytochrome P450 family 4 subfamily F member 22	Homo sapiens	88-91
35460591-8	2022	We propose that different regulation of C and N status through direct molecular signaling of NO3 - and/or different allocation of N between tree parts depending on N forms could account for the contrasting effects of NO3 - and tested here amino acids (Arg, Glu, Gln, and Leu) on autumn senescence.	Nitrogen	46-47	NBL1, DAN family BMP antagonist	Homo sapiens	93-96
35563717-5	2022	We found that a crude nonpolar extract of C. zofingiensis (ID name NAE_2022C), grown upon nitrogen deprivation, acts as a bioactive substance by inhibiting TNFR/NF-kappaB responses in human skin keratinocyte HaCaT cells.	Nitrogen	90-98	nuclear factor kappa B subunit 1	Homo sapiens	161-170
35451542-6	2022	Detection of N-glycosylation of OPN activated the NF-kappaB signaling pathway to regulate osteoblasts and osteoclasts.	Nitrogen	13-14	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	50-59
35451542-11	2022	OPN N-glycosylation modulated the expression of osteoclast- and osteoblast-associated factors through the NF-kappaB signaling pathway.	Nitrogen	4-5	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	106-115
35451542-12	2022	N-glycosylation of OPN promoted nuclear translocation of NF-kappaB in osteoclasts and osteoblasts.	Nitrogen	0-1	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	57-66
35137040-0	2022	Serum N-glycomics of a novel CDG-IIb patient reveals aberrant IgG glycosylation.	Nitrogen	6-7	mannosyl-oligosaccharide glucosidase	Homo sapiens	29-36
35007575-3	2022	A portion of the excess N is transported into underlying aquifers in the form of NO3-, which is potentially discharged to surface waters.	Nitrogen	24-25	NBL1, DAN family BMP antagonist	Homo sapiens	81-84
35007575-8	2022	This process, alongside the near absence of other anthropogenic N sources, results in a homogenised groundwater NO3- isotopic signature that allows for denitrification trends to be distinguished.	Nitrogen	64-65	NBL1, DAN family BMP antagonist	Homo sapiens	112-115
35455946-9	2022	N-glycosylation modification, plasma membrane localization, and ER stress resulted from the accumulation of mutant protein in ER, as shown by the higher expression of GRP78 and p-IRE1alpha.	Nitrogen	0-1	heat shock protein family A (Hsp70) member 5	Homo sapiens	167-172
35494076-5	2022	The mass spectrometry experiment showed that the N-glycosylation locus of CTSV are N221 and N292, glycosylated CTSV (band 43 kDa) was particularly expressed in lung cancer samples and correlated with lymph node metastasis.	Nitrogen	49-50	cathepsin V	Homo sapiens	74-78
35494076-5	2022	The mass spectrometry experiment showed that the N-glycosylation locus of CTSV are N221 and N292, glycosylated CTSV (band 43 kDa) was particularly expressed in lung cancer samples and correlated with lymph node metastasis.	Nitrogen	49-50	cathepsin V	Homo sapiens	111-115
35406805-0	2022	The Role of N-Glycosylation in the Intracellular Trafficking and Functionality of Neuronal Growth Regulator 1.	Nitrogen	12-13	neuronal growth regulator 1	Homo sapiens	82-109
35463394-6	2022	The values of NNI and NDC were from 0.54 to 1.28 kg ha-1 and from -28.13 to 21.99 kg ha-1 under the different treatments of N rate, respectively.	Nitrogen	124-125	Rho GTPase activating protein 45	Homo sapiens	85-89
35406805-3	2022	Endoglycosidase digestion of single NEGR1 mutants revealed that the wild type NEGR1 has six putative N-glycosylation sites partly organized in a Golgi-dependent manner.	Nitrogen	101-102	neuronal growth regulator 1	Homo sapiens	36-41
35406805-3	2022	Endoglycosidase digestion of single NEGR1 mutants revealed that the wild type NEGR1 has six putative N-glycosylation sites partly organized in a Golgi-dependent manner.	Nitrogen	101-102	neuronal growth regulator 1	Homo sapiens	78-83
35294933-2	2022	In this work, using first-principles calculations and a particle swarm optimization structural search method, four novel nitrogen-rich structures are predicted at high pressures, i.e., two ZnN3 phases with the same space group P-1 (low-pressure phase LP-ZnN3 and high-pressure phase HP-ZnN3), Cmm2-ZnN5 and Pcc2-ZnN6 , the energy density are estimated to be 1.41 kJ/g, 1.88 kJ/g, 4.07 kJ/g, and 2.60 kJ/g, respectively.	Nitrogen	121-129	cyclin dependent kinase inhibitor 2A	Homo sapiens	293-297
35409419-8	2022	Thus, N-linked glycosylation of CAR(V/28/28/3z) promotes stable membrane CAR expression, while having no effect on the expression or CAR-T cell activity of CAR(V/8a/8a/3z).	Nitrogen	6-7	nuclear receptor subfamily 1, group I, member 3	Mus musculus	32-35
35409419-8	2022	Thus, N-linked glycosylation of CAR(V/28/28/3z) promotes stable membrane CAR expression, while having no effect on the expression or CAR-T cell activity of CAR(V/8a/8a/3z).	Nitrogen	6-7	nuclear receptor subfamily 1, group I, member 3	Mus musculus	73-76
35041296-4	2022	We confirmed that fine-tuning lipophilicity and basic pKa by modifying the benzyl-group and introducing different substituents on the aliphatic nitrogen sidechain decreases both hERG inhibition and metabolic clearance.	Nitrogen	144-152	ETS transcription factor ERG	Homo sapiens	178-182
35294933-5	2022	In Cmm2-ZnN5 and Pcc2-ZnN6, nitrogen atoms polymerize into three-dimensional network structures and network layers under high pressures.	Nitrogen	28-36	cyclin dependent kinase inhibitor 2A	Homo sapiens	3-7
35150855-2	2022	The clay minerals and fired clay minerals treatments increased organic nitrogen contents and significantly reduced nitrogen loss, the loss was in order CK (52.61%) > M (47.15%) > I (45.90%) > M- (42.58%) > I- (40.59%).	Nitrogen	115-123	cytidine/uridine monophosphate kinase 1	Gallus gallus	152-154
35212163-3	2022	We initially found that the glycolytic inhibitor 2-deoxy-d-glucose (2-DG), a simple monosaccharide, attenuated cellular responses to IL-6 by inhibiting N-linked glycosylation of the IL-6 receptor gp130.	Nitrogen	152-153	interleukin 6	Mus musculus	133-137
35146943-2	2022	The study aimed to investigate the relationship between the blood urea nitrogen to serum albumin ratio (BAR) and the prognosis of patients with CHF admitted to the ICU.	Nitrogen	71-79	albumin	Homo sapiens	89-96
35229477-1	2022	Ammonium (NH4 + ) and nitrate (NO3 - ) are major inorganic nitrogen (N) source for plants.	Nitrogen	59-67	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
35229477-1	2022	Ammonium (NH4 + ) and nitrate (NO3 - ) are major inorganic nitrogen (N) source for plants.	Nitrogen	69-70	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
35007660-7	2022	I found that the N-glycosylation of CLR ECD N123 was the most critical for inhibiting MBP interaction with the mutated peptide ligands.	Nitrogen	17-18	calcitonin receptor like receptor	Homo sapiens	36-39
35007660-10	2022	Here, I provided evidence that N-glycosylation of the CGRP receptor ECD inhibited the tag protein interaction suggesting an additional function of N-glycosylation in the MBP-fused CGRP receptor ECD.	Nitrogen	147-148	calcitonin related polypeptide alpha	Homo sapiens	180-184
35212163-3	2022	We initially found that the glycolytic inhibitor 2-deoxy-d-glucose (2-DG), a simple monosaccharide, attenuated cellular responses to IL-6 by inhibiting N-linked glycosylation of the IL-6 receptor gp130.	Nitrogen	152-153	interleukin 6	Homo sapiens	182-186
35212163-3	2022	We initially found that the glycolytic inhibitor 2-deoxy-d-glucose (2-DG), a simple monosaccharide, attenuated cellular responses to IL-6 by inhibiting N-linked glycosylation of the IL-6 receptor gp130.	Nitrogen	152-153	interleukin 6 signal transducer	Mus musculus	196-201
35119196-2	2022	A 2D graphdiyne (GDY) layer grown on the surface of zeolitic imidazolate framework nanocubes (ZIFNC@GDY) forms a novel structure of a perfect "donor-bridge-acceptor" interface, in which the ZIFNC and GDY act as electron donor and acceptor, respectively, linked by the sp-C-Co and sp-C-N bonds as bridges.	Nitrogen	285-286	surfactant protein C	Homo sapiens	268-272
35193747-8	2022	Further analysis revealed that QQS expression and overexpression of NtNF-YC4 strongly repressed expression of genes such as sugar transporter SWEET10 and Flowering Locus T (FT), suggesting involvement of SWEET10 and FT in the QQS and NF-YC4 mediated carbon and nitrogen allocation in tobacco.	Nitrogen	261-269	nuclear factor Y, subunit C4	Arabidopsis thaliana	234-240
35193747-1	2022	Qua-Quine Starch (QQS), an orphan gene exclusively found in Arabidopsis thaliana, interacts with Nuclear Factor Y subunit C4 (NF-YC4) and regulates carbon and nitrogen allocation in different plant species.	Nitrogen	159-167	qua-quine starch	Arabidopsis thaliana	18-21
35193747-8	2022	Further analysis revealed that QQS expression and overexpression of NtNF-YC4 strongly repressed expression of genes such as sugar transporter SWEET10 and Flowering Locus T (FT), suggesting involvement of SWEET10 and FT in the QQS and NF-YC4 mediated carbon and nitrogen allocation in tobacco.	Nitrogen	261-269	qua-quine starch	Arabidopsis thaliana	226-229
35119196-2	2022	A 2D graphdiyne (GDY) layer grown on the surface of zeolitic imidazolate framework nanocubes (ZIFNC@GDY) forms a novel structure of a perfect "donor-bridge-acceptor" interface, in which the ZIFNC and GDY act as electron donor and acceptor, respectively, linked by the sp-C-Co and sp-C-N bonds as bridges.	Nitrogen	285-286	surfactant protein C	Homo sapiens	280-284
35043524-5	2022	Crystal structures of (CpRu(ArX n )) + salts show that the (CpRu(ArI n )) + cations are strong, charge-assisted XB donors analogous to iodopyridinium cations.	Nitrogen	32-36	aristaless related homeobox	Homo sapiens	28-31
35285615-7	2022	N-Glycosylation patterns of both haptoglobin phenotypes were found to be consistent with bi- and triantennary structures of complex type that exhibit significant level of fucosylation and sialylation.	Nitrogen	0-1	haptoglobin	Homo sapiens	33-44
35274660-2	2022	The magnetic anisotropy of sixteen seven-coordinate high-spin CoII complexes with O, N, Cl and I donors was investigated with state-of-the-art ab initio CASSCF/NEVPT2 calculations and compared with experimental data.	Nitrogen	85-86	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	62-66
35391786-7	2022	Lipid profiles from older mice contain greater total and n-6 fatty acids than normal diet (ND)-fed young mice; however, surprisingly, young Cyp2b-null mice contain high n-6 : n-3 ratios.	Nitrogen	169-170	cytochrome P450, family 2, subfamily b, polypeptide 9	Mus musculus	140-145
35331277-6	2022	Two calcium channels of L-type voltage-gated calcium channels (L-VGCCs) in plasma membrane and ryanodine receptor (RyR) in endoplasmic reticulum (ER) took part in N-GQDs inducing cytosolic calcium overload.	Nitrogen	163-164	ryanodine receptor 1, skeletal muscle	Mus musculus	95-113
35331277-6	2022	Two calcium channels of L-type voltage-gated calcium channels (L-VGCCs) in plasma membrane and ryanodine receptor (RyR) in endoplasmic reticulum (ER) took part in N-GQDs inducing cytosolic calcium overload.	Nitrogen	163-164	ryanodine receptor 1, skeletal muscle	Mus musculus	115-118
35415365-4	2022	It was confirmed that the small amounts of alpha-Fe2O3 can availably facilitate exfoliation of bulk SPI, resulting in a transformation of SPI from bulk to 2D layered composite that illustrates tight interface through the coordination Fe-N bond and an all-solid-state direct Z-scheme junction.	Nitrogen	237-238	chromogranin A	Homo sapiens	100-103
35415365-4	2022	It was confirmed that the small amounts of alpha-Fe2O3 can availably facilitate exfoliation of bulk SPI, resulting in a transformation of SPI from bulk to 2D layered composite that illustrates tight interface through the coordination Fe-N bond and an all-solid-state direct Z-scheme junction.	Nitrogen	237-238	chromogranin A	Homo sapiens	138-141
35391727-12	2022	SntA modeling revealed that Y530 and Y633 form a sandwich with the nitrogen base of nucleotidic ligands in the substrate-binding site.	Nitrogen	67-75	heme-binding protein SntA	Escherichia coli	0-4
35486466-4	2022	As to synthetic wastewater, the optimal nitrogen load (NL) for MEC-1 and -2 was 1.25 and 0.75 gNH4+-N d-1, respectively.	Nitrogen	40-48	ATR serine/threonine kinase	Homo sapiens	63-75
35433445-0	2022	N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC.	Nitrogen	0-1	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	37-42
35433445-3	2022	However, whether TIM-4 is modified by N-glycosylation and the role of TIM-4 N-glycosylation in NSCLC remains largely unknown.	Nitrogen	38-39	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	17-22
35433445-3	2022	However, whether TIM-4 is modified by N-glycosylation and the role of TIM-4 N-glycosylation in NSCLC remains largely unknown.	Nitrogen	76-77	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	70-75
35433445-4	2022	In the current study, we reported that TIM-4 was extensively N-glycosylated at Asn291.	Nitrogen	61-62	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	39-44
35433445-5	2022	After the removal of N-glycosylation, the stability of TIM-4 protein was decreased and TIM-4 was more susceptible to degradation by ER-localized ubiquitin ligase-mediated ERAD.	Nitrogen	21-22	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	55-60
35433445-5	2022	After the removal of N-glycosylation, the stability of TIM-4 protein was decreased and TIM-4 was more susceptible to degradation by ER-localized ubiquitin ligase-mediated ERAD.	Nitrogen	21-22	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	87-92
35433445-7	2022	In summary, the present study identifies TIM-4 N-glycosylation and its role in NSCLS migration, which would provide a valuable biomarker for developing drugs targeting N-glycosylation at Asn291 on TIM-4.	Nitrogen	47-48	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	41-46
35433445-7	2022	In summary, the present study identifies TIM-4 N-glycosylation and its role in NSCLS migration, which would provide a valuable biomarker for developing drugs targeting N-glycosylation at Asn291 on TIM-4.	Nitrogen	47-48	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	197-202
35433445-7	2022	In summary, the present study identifies TIM-4 N-glycosylation and its role in NSCLS migration, which would provide a valuable biomarker for developing drugs targeting N-glycosylation at Asn291 on TIM-4.	Nitrogen	168-169	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	41-46
35433445-7	2022	In summary, the present study identifies TIM-4 N-glycosylation and its role in NSCLS migration, which would provide a valuable biomarker for developing drugs targeting N-glycosylation at Asn291 on TIM-4.	Nitrogen	168-169	T cell immunoglobulin and mucin domain containing 4	Homo sapiens	197-202
35234763-1	2022	By using I2 as an oxidant and CH3CN as a reaction medium, few-layer Mg-deficient borophene nanosheets (FBN) with a stoichiometric ratio of Mg0.22B2 are prepared by oxidizing MgB2 in a mixture of CH3CN and HCl for 14 days under nitrogen protection and followed by ultrasonic delaminating in CH3CN for 2 h. The prepared FBN possess a two-dimensional flake morphology, and they show a clear interference fringe with a d-spacing of 0.251 nm corresponding to the (208) plane of rhombohedral boron.	Nitrogen	227-235	secretoglobin family 2A member 1	Homo sapiens	174-178
35369507-1	2022	High nitrogen utilization efficiency (NUE) is important for increasing milk protein production and decreasing the feed nitrogen cost and nitrogen emission to the environment.	Nitrogen	5-13	casein beta	Bos taurus	71-83
35371181-4	2022	Total N uptake was between 7.88 and 29.27 kg ha-1 for straw and 41.85 and 95.27 kg ha-1 for grain.	Nitrogen	6-7	Rho GTPase activating protein 45	Homo sapiens	45-49
35340411-13	2022	Functional enrichment analysis showed that the top 100 positively and top 100 negatively GCG-correlated genes were mainly enriched in three signaling pathways including ribosome, nitrogen metabolism, and proximal tubule bicarbonate reclamation.	Nitrogen	179-187	glucagon	Homo sapiens	89-92
35230820-3	2022	Pt nanoparticles (Pt NPs) were grown in situ on the coordination sites for metal ions of beta-CD to prepare the beta-CD-Pt nanocomposite, which could not only enrich co-reactant 3-(dibutylamino) propylamine (TDBA) highly efficiently through its hydrophobic cavity but also immobilize TDBA via the Pt-N bond.	Nitrogen	300-301	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	89-96
35371129-7	2022	From these results, we conclude that N application at 150 and 225 kg ha-1 under straw incorporation was the most effective fertilization method in achieving the higher photosynthetic characteristics, improving NUE and grain yield.	Nitrogen	37-38	Rho GTPase activating protein 45	Homo sapiens	69-73
35371997-15	2022	Our combined results point to a context-dependent effect of ST6Gal1 expression on BCP-ALL cells, which is discussed within the framework of its activity as an enzyme with many N-linked glycoprotein substrates.	Nitrogen	176-177	beta galactoside alpha 2,6 sialyltransferase 1	Mus musculus	60-67
35371181-4	2022	Total N uptake was between 7.88 and 29.27 kg ha-1 for straw and 41.85 and 95.27 kg ha-1 for grain.	Nitrogen	6-7	Rho GTPase activating protein 45	Homo sapiens	83-87
35230820-3	2022	Pt nanoparticles (Pt NPs) were grown in situ on the coordination sites for metal ions of beta-CD to prepare the beta-CD-Pt nanocomposite, which could not only enrich co-reactant 3-(dibutylamino) propylamine (TDBA) highly efficiently through its hydrophobic cavity but also immobilize TDBA via the Pt-N bond.	Nitrogen	300-301	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	112-119
35336811-2	2022	These mechanisms include synthesis of auxins, especially indoleacetic acid, which directly promotes plant growth; synthesis of antioxidant enzymes such as catalase, superoxide dismutase and peroxidase, which prevents the deleterious effects of reactive oxygen species; synthesis of small molecule osmolytes, e.g., trehalose and proline, which structures the water content within plant and bacterial cells and reduces plant turgor pressure; nitrogen fixation, which directly improves plant growth; synthesis of exopolysaccharides, which protects plant cells from water loss and stabilizes soil aggregates; synthesis of antibiotics, which protects stress-debilitated plants from soil pathogens; and synthesis of the enzyme 1-aminocyclopropane-1-carboxylate (ACC) deaminase, which lowers the level of ACC and ethylene in plants, thereby decreasing stress-induced plant senescence.	Nitrogen	440-448	catalase	Homo sapiens	155-163
35226486-1	2022	Mesoporous Pt-Pd bimetallic core-shell nanospheres (mPd@Pt NSs) with palladium-rich cores and platinum-rich shells were synthesized via a simple, two-step, wet chemical strategy mediated by nitrogen-doped carbon dots.	Nitrogen	190-198	mevalonate (diphospho) decarboxylase	Mus musculus	52-55
35179893-2	2022	Introducing a nitrogen atom into the aromatic portion of the tetrahydroisoquinoline ring led to several heterocyclic variants including the 5,6,7,8-tetrahydro-1,6-naphthyridine series, greatly reducing the inhibition of the CYP 2D6 enzyme.	Nitrogen	14-22	cytochrome P450 family 2 subfamily D member 6	Homo sapiens	224-231
35337137-4	2022	Herein, we discovered new SIRT1-activating derivatives, characterized by phenolic rings spaced by sulfur, nitrogen or oxygen-based central linkers.	Nitrogen	106-114	sirtuin 1	Rattus norvegicus	26-31
35192343-3	2022	These compounds are also prepared from cyclic six-membered (tap)PdCl2 (5; tap = triazapentadiene) or formamidinium salts (6a-6c) with Pd(OAc)2/NaOAc in acetonitrile, whereas the direct reaction of 2 with acetonitrile or acrylonitrile resulted in palladium black or an acyclic C-N-coupled product (3).	Nitrogen	278-279	SEC14 like lipid binding 2	Homo sapiens	60-63
35258180-3	2022	Compared with that during clean days, SNA (SO42-, NO3-, and NH4+) in PM1 increased by 14.5% during heavy pollution, and SNA in PM2.5 increased by 15.2%; the nitrogen oxidation rate (NOR) in particular increased by three times on heavy pollution days.	Nitrogen	157-165	snail family transcriptional repressor 1	Homo sapiens	38-41
35258180-3	2022	Compared with that during clean days, SNA (SO42-, NO3-, and NH4+) in PM1 increased by 14.5% during heavy pollution, and SNA in PM2.5 increased by 15.2%; the nitrogen oxidation rate (NOR) in particular increased by three times on heavy pollution days.	Nitrogen	157-165	snail family transcriptional repressor 1	Homo sapiens	120-123
35335137-0	2022	N-Glycosylation Patterns across the Age-Related Macular Degeneration Spectrum.	Nitrogen	0-1	renin binding protein	Homo sapiens	36-39
35192343-3	2022	These compounds are also prepared from cyclic six-membered (tap)PdCl2 (5; tap = triazapentadiene) or formamidinium salts (6a-6c) with Pd(OAc)2/NaOAc in acetonitrile, whereas the direct reaction of 2 with acetonitrile or acrylonitrile resulted in palladium black or an acyclic C-N-coupled product (3).	Nitrogen	278-279	SEC14 like lipid binding 2	Homo sapiens	74-77
35247980-8	2022	Logistic regression analysis indicated that diabetes (OR2.908, 95%CI1.844 ~ 4.231), pulmonary infection(OR3.755, 95%CI2.831 ~ 4.987), albumin <= 24 g/L (OR1.923, 95%CI1.214 ~ 2.355), serum creatinine >= 90 mumol/L (OR2.517, 95%CI2.074 ~ 3.182), blood urea nitrogen >= 6.5 mmol/L (OR1.686, 95%CI1.208 ~ 2.123), uric acid >= 390 mumol/L (OR2.755, 95%CI2.131 ~ 3.371), renal tubular casts(OR1.796, 95%CI1.216 ~ 2.208) were the independently influencing factors of AKI in PNS patients (all P < 0.05).	Nitrogen	256-264	albumin	Homo sapiens	134-141
35311117-8	2022	Altogether, TGF-beta1 activated c-Jun/STT3A signaling pathway to promote N-glycosylation of PD-L1, thus further facilitating immune evasion and reducing the efficacy of cancer immunotherapy.	Nitrogen	73-74	transforming growth factor beta 1	Homo sapiens	12-21
35149265-8	2022	Docking studies suggested that the endocyclic nitrogen of the quinoline ring, and exocyclic nitrogen of the sulfonamide functional group are coordinate with Zn(II) ion at active sites of NDM-1.	Nitrogen	46-54	Beta-lactamase	Escherichia coli	187-192
35360339-5	2022	Moreover, a single application of high nitrogen at 450 kg ha-1 reduced the activities of plant nitrogen metabolism-related enzymes, however; the integration of biochar at 30 t ha-1 compensated the high nitrogen toxicity and improved the activities of nitrate reductase (NR), nitrite reductase NIR, glutamate synthase (GS) and glutamine synthetase (GOGAT) at seedling stage (SS) and flowering stage (FS) in both years.	Nitrogen	95-103	Rho GTPase activating protein 45	Homo sapiens	58-62
35360339-6	2022	The integration of biochar at 30 t ha-1 with nitrogen at 450 kg ha-1 induced synergetic effects on rapeseed growth through sorption of excessive nitrogen in soil and significantly improved the plant height up to 11 and 18%, pods plant-1 39 and 32% and grain yield plant-1 54 and 64%, respectively, during the first and second year.	Nitrogen	45-53	Rho GTPase activating protein 45	Homo sapiens	64-68
35360339-6	2022	The integration of biochar at 30 t ha-1 with nitrogen at 450 kg ha-1 induced synergetic effects on rapeseed growth through sorption of excessive nitrogen in soil and significantly improved the plant height up to 11 and 18%, pods plant-1 39 and 32% and grain yield plant-1 54 and 64%, respectively, during the first and second year.	Nitrogen	145-153	Rho GTPase activating protein 45	Homo sapiens	35-39
35360339-6	2022	The integration of biochar at 30 t ha-1 with nitrogen at 450 kg ha-1 induced synergetic effects on rapeseed growth through sorption of excessive nitrogen in soil and significantly improved the plant height up to 11 and 18%, pods plant-1 39 and 32% and grain yield plant-1 54 and 64%, respectively, during the first and second year.	Nitrogen	145-153	Rho GTPase activating protein 45	Homo sapiens	64-68
35149265-8	2022	Docking studies suggested that the endocyclic nitrogen of the quinoline ring, and exocyclic nitrogen of the sulfonamide functional group are coordinate with Zn(II) ion at active sites of NDM-1.	Nitrogen	92-100	Beta-lactamase	Escherichia coli	187-192
35166290-6	2022	(cis-Rh2(OAc)2(tfa)2) and (Rh2(OAc)4) bind the N atoms of His side chains of RNase A at the axial position; however the fluorine-containing compound rapidly loses its tfa ligands, while (Rh2(OAc)4) can retain the acetate ligands upon protein binding.	Nitrogen	47-48	ribonuclease pancreatic	Bos taurus	77-84
35190688-1	2022	High-redox-potential reactive oxygen species and reactive nitrogen species (ROS/RNS), generated by NADPH oxidase-2 (NOX2), myeloperoxidase (MPO) and related enzymes, are key effector molecules of innate immunity.	Nitrogen	58-66	myeloperoxidase	Homo sapiens	123-138
35044684-1	2022	Glutamine synthetase (GS, EC 6.3.1.2, L-glutamate: ammonia ligase) is an essential enzyme in nitrogen assimilation.	Nitrogen	93-101	glutamate-ammonia ligase	Homo sapiens	0-20
35044684-1	2022	Glutamine synthetase (GS, EC 6.3.1.2, L-glutamate: ammonia ligase) is an essential enzyme in nitrogen assimilation.	Nitrogen	93-101	glutamate-ammonia ligase	Homo sapiens	22-24
35194116-4	2022	Judiciously introduced nitrogen-rich semiconducting PhPTz brings multiple advantages to the device-(1) efficiently immobilizes anti-CEA via synergistic H-bonding with peptide and N-glycal units and (2) transports the charge density variations, originated upon antibody-antigen interactions, to the rGO layer.	Nitrogen	23-31	CEA cell adhesion molecule 3	Homo sapiens	132-135
35194116-4	2022	Judiciously introduced nitrogen-rich semiconducting PhPTz brings multiple advantages to the device-(1) efficiently immobilizes anti-CEA via synergistic H-bonding with peptide and N-glycal units and (2) transports the charge density variations, originated upon antibody-antigen interactions, to the rGO layer.	Nitrogen	179-180	CEA cell adhesion molecule 3	Homo sapiens	132-135
35104503-8	2022	Mutational and enzymatic blockade of N-glycosylation in the gamma1-3 subunits resulted in a reduction or loss of BK channel modulation by gamma subunits.	Nitrogen	37-38	tryptophanyl-tRNA synthetase 1	Homo sapiens	60-68
35104503-9	2022	Finally, by analyzing their expression in whole cells and on the plasma membrane, we found that blockade of N-glycosylation drastically reduced total expression of the gamma2 subunit and the cell surface expression of the gamma1 and gamma3 subunits.	Nitrogen	108-109	tryptophanyl-tRNA synthetase 1	Homo sapiens	168-174
34787344-1	2022	RATIONALE: Analyses of the isotope ratios of nitrogen (15 N/14 N) and oxygen (18 O/16 O) in nitrate (NO3 - ) with the denitrifier method require relatively high sample volumes at low concentrations (<= 1 muM) to afford sufficient analyte for mass spectrometry, resulting in isotopic offsets compared to more concentrated samples of the same isotopic composition.	Nitrogen	45-53	NBL1, DAN family BMP antagonist	Homo sapiens	101-104
35074339-0	2022	Reduction of photoswitched, nitrogen bridged N-acetyl diazocines limits inhibition of 17betaHSD3 activity in transfected human embryonic kidney 293 cells.	Nitrogen	28-36	hydroxysteroid 17-beta dehydrogenase 3	Homo sapiens	86-96
35211808-0	2022	Defective IGF-1 prohormone N-glycosylation and reduced IGF-1 receptor signaling activation in congenital disorders of glycosylation.	Nitrogen	27-28	insulin like growth factor 1	Homo sapiens	10-15
35190688-1	2022	High-redox-potential reactive oxygen species and reactive nitrogen species (ROS/RNS), generated by NADPH oxidase-2 (NOX2), myeloperoxidase (MPO) and related enzymes, are key effector molecules of innate immunity.	Nitrogen	58-66	myeloperoxidase	Homo sapiens	140-143
35176981-5	2022	Then, DNA/LL-37 complexes were prepared by co-incubation of pEGFP-nef-vpr with LL-37 for 45 minutes at different nitrogen to phosphate (N/P) ratios.	Nitrogen	136-137	cathelicidin antimicrobial peptide	Homo sapiens	10-15
35063154-9	2022	Specifically, APPI tended to ionize less oxidized and N-containing molecules, and compounds with high concentrations of unsaturation or aromatics, while ESI was more prone to detect highly oxidized compounds consisting of large O/C ratios.	Nitrogen	54-55	amyloid beta precursor protein	Homo sapiens	14-18
35173168-4	2022	Lin28B enables neutrophil recruitment and N2 conversion.	Nitrogen	42-44	lin-28 homolog B	Homo sapiens	0-6
35177661-7	2022	Based on the predicted maximum profit, the optimal combinations of N application and planting density were 199 kg ha-1 and 81,081 plants ha-1 in 2017, and 205 kg ha-1 and 84,782 plants ha-1 in 2018.	Nitrogen	67-68	1,4-alpha-glucan-branching enzyme 2, chloroplastic/amyloplastic	Zea mays	114-118
35219226-3	2022	We have performed a meta-analysis of Blood Urea Nitrogen to Albumin (BUN/ALB) ratio as a predictive factor regarding patients with pneumonia.	Nitrogen	48-56	albumin	Homo sapiens	73-76
35145079-3	2022	Grx1 deficiency derepresses distinct expression patterns of reactive oxygen species and reactive nitrogen species generators in male versus female macrophages, poising female but not male macrophages for increased peroxynitrate production.	Nitrogen	97-105	glutaredoxin	Mus musculus	0-4
35075865-5	2022	A good linear positive correlation (R2=0.988) between the projected area of the erythrine zone in the inner layer and the specific nitrogen removal rate of granules was found, which provide a simple method to estimate the activity of the PN/A granules.	Nitrogen	131-139	U6 snRNA biogenesis phosphodiesterase 1	Homo sapiens	238-240
35204748-4	2022	In addition, nitrogen species (nitrotyrosine, iNOS, eNOS) and inflammation markers (IL-6, NFkB, and S100 protein) were increased in granulocytes of CML while anti-inflammatory levels of IL-10 were decreased in plasma.	Nitrogen	13-21	nitric oxide synthase 3	Homo sapiens	52-56
35371547-4	2022	The CoII cations are coordinated by four N atoms of the cyclam ligand and two trans-S atoms of the tetra-thio-anti-monate anion within slightly distorted octa-hedra.	Nitrogen	41-42	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	4-8
35386814-4	2022	A degradable hybrid coating consisting of poly(lactide-co-glycolide) and alendronate (ALN) loaded nano-hydroxyapatite is deposited on PEEK and then interleukin-4 (IL-4) is grafted onto the outer surface of the hybrid coating with the aid of N2 plasma immersion ion implantation and subsequent immersion in IL-4 solution.	Nitrogen	241-243	interleukin 4	Homo sapiens	148-161
35091578-3	2022	Here, we show that, in Arabidopsis thaliana, either disruption of the cell wall-localized ferroxidase LPR2 or a decrease in iron supplementation efficiently alleviates the growth inhibition of primary roots in response to NH4+ as the N source.	Nitrogen	234-235	Cupredoxin superfamily protein	Arabidopsis thaliana	102-106
35051764-2	2022	Identifying NO3- sources and transformations is the key for understanding nitrogen pathways, and also for effectively controlling diffuse NO3- pollution.	Nitrogen	74-82	NBL1, DAN family BMP antagonist	Homo sapiens	12-15
35173763-1	2021	The N-reductive enzyme system (NRES), composed of MARC1, MARC2, CYB5, and CYB5R, is responsible for the reduction of N-oxygenated compounds and participates in several physiological processes.	Nitrogen	4-5	mitochondrial amidoxime reducing component 1	Homo sapiens	50-55
35173763-1	2021	The N-reductive enzyme system (NRES), composed of MARC1, MARC2, CYB5, and CYB5R, is responsible for the reduction of N-oxygenated compounds and participates in several physiological processes.	Nitrogen	117-118	mitochondrial amidoxime reducing component 1	Homo sapiens	50-55
35051764-6	2022	The MixSIAR outputs revealed that the long-term application of synthetic NH4+ fertilizer (36.6%) and soil organic nitrogen (28.0%) were the main contributors to NO3- pollution, followed by synthetic NO3- fertilizer (16.8%) and domestic sewage and manure (15.1%), whereas NO3- in precipitation (3.44%) played a less important role.	Nitrogen	114-122	NBL1, DAN family BMP antagonist	Homo sapiens	161-164
35163124-8	2022	Under ABA treatment, the NR proteins are degraded via a 26S-proteasome dependent manner, while the transcriptional regulation is the main manner to rapidly reduce the NIA1 levels under nitrogen deficiency and NaCl stress conditions.	Nitrogen	185-193	nitrate reductase 1	Arabidopsis thaliana	167-171
35084690-0	2022	Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)n. Spinocerebellar ataxia type 31 (SCA31), an autosomal-dominant neurodegenerative disorder characterized by progressive cerebellar ataxia with Purkinje cell degeneration, is caused by a heterozygous 2.5-3.8 kilobase penta-nucleotide repeat of (TTCCA)n in intron 11 of the thymidine kinase 2 (TK2) gene.	Nitrogen	409-411	cytochrome c oxidase I, mitochondrial	Mus musculus	45-50
35425364-5	2022	Herein, we report the EDA-NOCV analyses of the previously reported dinitrogen-bonded neutral molecular complex (cAACR)2Fe0-N2 (1) and mono-anionic complex (cAACR)2Fe-1-N2 (2) to give deeper insight of the Fe-N2 interacting orbitals and corresponding pairwise intrinsic interaction energies (cAACR = cyclic alkyl(amino) carbene; R = Dipp or Me).	Nitrogen	67-77	nudix hydrolase 3	Homo sapiens	332-336
35095967-15	2021	This may explain why an increase in the NH4 +/NO3 - ratio significantly reduced root NO3 --N content but increased NH4 +-N content.	Nitrogen	91-92	NBL1, DAN family BMP antagonist	Homo sapiens	46-49
35044789-10	2022	Overall, our results indicate that tumor N-glycosylation regulates the quality and magnitude of CAR T cell responses, paving the way for the rational design of improved therapies against solid malignancies.	Nitrogen	41-42	nuclear receptor subfamily 1, group I, member 3	Mus musculus	96-99
34935827-0	2022	Theoretical mechanistic insights into dinitrogen cleavage by a dititanium hydride complex bearing PNP-pincer ligands.	Nitrogen	38-48	purine nucleoside phosphorylase	Homo sapiens	98-101
34935827-1	2022	The mechanism of dinitrogen cleavage by a PNP-coordinated dititanium polyhydride complex has been computationally investigated.	Nitrogen	17-27	purine nucleoside phosphorylase	Homo sapiens	42-45
35173832-4	2022	Interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in mouse serum were detected by Enzyme-linked immunosorbent assay (ELISA); fibronectin (FN) and type I collagen (Col-I) in renal tissue were detected by Western blotting; serum creatinine (Cr) and blood urea nitrogen (BUN) were analyzed by kits.	Nitrogen	273-281	interleukin 6	Mus musculus	0-13
35173832-4	2022	Interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in mouse serum were detected by Enzyme-linked immunosorbent assay (ELISA); fibronectin (FN) and type I collagen (Col-I) in renal tissue were detected by Western blotting; serum creatinine (Cr) and blood urea nitrogen (BUN) were analyzed by kits.	Nitrogen	273-281	tumor necrosis factor	Mus musculus	25-52
35173832-4	2022	Interleukin 6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) in mouse serum were detected by Enzyme-linked immunosorbent assay (ELISA); fibronectin (FN) and type I collagen (Col-I) in renal tissue were detected by Western blotting; serum creatinine (Cr) and blood urea nitrogen (BUN) were analyzed by kits.	Nitrogen	273-281	tumor necrosis factor	Homo sapiens	54-63
35095967-1	2021	Wheat growth and nitrogen (N) uptake gradually decrease in response to high NH4 +/NO3 - ratio.	Nitrogen	17-25	NBL1, DAN family BMP antagonist	Homo sapiens	82-85
35095967-1	2021	Wheat growth and nitrogen (N) uptake gradually decrease in response to high NH4 +/NO3 - ratio.	Nitrogen	27-28	NBL1, DAN family BMP antagonist	Homo sapiens	82-85
35023570-7	2022	Besides, the irrigation amount of 240 mm and nitrogen application amount of 180-210 kg ha-1 are the best to maintain high yield, high resource utilization rate, and low environmental pollution in this area.	Nitrogen	45-53	Rho GTPase activating protein 45	Homo sapiens	87-91
35095967-15	2021	This may explain why an increase in the NH4 +/NO3 - ratio significantly reduced root NO3 --N content but increased NH4 +-N content.	Nitrogen	91-92	NBL1, DAN family BMP antagonist	Homo sapiens	85-88
35095967-15	2021	This may explain why an increase in the NH4 +/NO3 - ratio significantly reduced root NO3 --N content but increased NH4 +-N content.	Nitrogen	121-122	NBL1, DAN family BMP antagonist	Homo sapiens	46-49
35095972-0	2021	Shade Avoidance 3 Mediates Crosstalk Between Shade and Nitrogen in Arabidopsis Leaf Development.	Nitrogen	55-63	tryptophan aminotransferase of Arabidopsis 1	Arabidopsis thaliana	0-17
35095972-6	2021	Both hypocotyl elongation and leaf expansion promoted by the shade treatment were reduced by the high-N treatment; high-N-induced leaf narrowing and thickening were reduced by the shade treatment; and all of these developmental changes were largely compromised in the sav3 mutant.	Nitrogen	120-121	tryptophan aminotransferase of Arabidopsis 1	Arabidopsis thaliana	268-272
35095972-7	2021	Shade treatment promoted SAV3 expression, while high-N treatment repressed SAV3 expression, which then increased or decreased auxin accumulation in cotyledons/leaves, respectively.	Nitrogen	53-54	tryptophan aminotransferase of Arabidopsis 1	Arabidopsis thaliana	75-79
35095972-8	2021	SAV3 also regulates chlorophyll accumulation and nitrogen assimilation and thus may function as a master switch responsive to multiple environmental stimuli.	Nitrogen	49-57	tryptophan aminotransferase of Arabidopsis 1	Arabidopsis thaliana	0-4
35055927-3	2022	Based on the above two patterns, atmospheric nitrogen or nitrogenous waste (e.g., uric acid, urea) is converted into ammonia, which in turn is incorporated into the organism via the glutamine synthetase and glutamate synthase pathways.	Nitrogen	45-53	glutamate-ammonia ligase	Homo sapiens	182-202
35095982-1	2021	Nitrate nitrogen ( NO 3 -  -N) in the soil is one of the important nutrients for growing crops.	Nitrogen	8-16	NBL1, DAN family BMP antagonist	Homo sapiens	19-23
34999954-6	2022	Although it has been demonstrated that the transporter and substrate specificities of SLC10A7, if any, differ from those of the main members of the protein family, SLC10A7 seems to play a role in Ca2+ regulation and is involved in proper glycosaminoglycan biosynthesis, especially heparan-sulfate, and N-glycosylation.	Nitrogen	302-303	solute carrier family 10 member 7	Homo sapiens	86-93
34989513-2	2022	Four types of modified zeolites(AlCl3, Al(NO3)3, Al2(SO4)3, and KAl(SO4)2) and a biofilm system were investigated for the removal of ammonia nitrogen from overlaying water.	Nitrogen	141-149	anosmin 1	Homo sapiens	64-67
34999954-6	2022	Although it has been demonstrated that the transporter and substrate specificities of SLC10A7, if any, differ from those of the main members of the protein family, SLC10A7 seems to play a role in Ca2+ regulation and is involved in proper glycosaminoglycan biosynthesis, especially heparan-sulfate, and N-glycosylation.	Nitrogen	302-303	solute carrier family 10 member 7	Homo sapiens	164-171
34983878-6	2022	In this study, breast cancer cells were transfected with N-glycosylation mutation EpCAM plasmid to express deglycosylated EpCAM.	Nitrogen	57-58	epithelial cell adhesion molecule	Homo sapiens	82-87
34983878-6	2022	In this study, breast cancer cells were transfected with N-glycosylation mutation EpCAM plasmid to express deglycosylated EpCAM.	Nitrogen	57-58	epithelial cell adhesion molecule	Homo sapiens	122-127
35009131-3	2022	Since these genes are members of the NRT2 family of nitrate transporters, the nitrogen assimilatory pathway could be involved in growth promotion by STM196.	Nitrogen	78-86	nitrate transporter 2:1	Arabidopsis thaliana	37-41
35022194-4	2022	METHODS: We examined the contribution of immunosuppressive myeloid cells expressing arginase 1 and nitric oxide synthase 2 in building up a reactive nitrogen species (RNS)-dependent chemical barrier and shaping the PDAC immune landscape.	Nitrogen	149-157	nitric oxide synthase 2	Homo sapiens	99-122
35173546-5	2022	CD137-positive lymphatic vessels were involved in the development process of IgA nephropathy and positively correlated with serum creatinine, serum urea nitrogen, serum uric acid, and urinary 24 h total protein.	Nitrogen	153-161	CD79a molecule	Homo sapiens	77-80
35173935-9	2022	Heavy-atom tunneling also results in a normal N-H(D) secondary KIE above 100 K even though the increase in hybridization from sp2 to sp3 at nitrogen should cause an inverse KIE classically.	Nitrogen	140-148	Sp2 transcription factor	Homo sapiens	126-129
35173935-9	2022	Heavy-atom tunneling also results in a normal N-H(D) secondary KIE above 100 K even though the increase in hybridization from sp2 to sp3 at nitrogen should cause an inverse KIE classically.	Nitrogen	140-148	Sp3 transcription factor	Homo sapiens	133-136
35140555-4	2022	In lab-scale bioreactor fermentations, an aceE silenced strain successfully produced pyruvate under fully aerobic conditions during the exponential phase, but loss of productivity occurred during a subsequent nitrogen-limited phase.	Nitrogen	209-217	pyruvate dehydrogenase E1 component	Escherichia coli str. K-12 substr. MG1655	42-46
35140555-6	2022	Combinatorial targeting of the promoter regions of both aceE and pdhR in E. coli MG1655 pdCas9 psgRNA_aceE_234_pdhR_329 resulted in the stable aerobic production of pyruvate with non-growing cells at YP/S  =  0.36 +- 0.029 gPyruvate/gGlucose in lab-scale bioreactors throughout an extended nitrogen-limited production phase.	Nitrogen	290-298	pyruvate dehydrogenase E1 component	Escherichia coli str. K-12 substr. MG1655	56-60
35140555-6	2022	Combinatorial targeting of the promoter regions of both aceE and pdhR in E. coli MG1655 pdCas9 psgRNA_aceE_234_pdhR_329 resulted in the stable aerobic production of pyruvate with non-growing cells at YP/S  =  0.36 +- 0.029 gPyruvate/gGlucose in lab-scale bioreactors throughout an extended nitrogen-limited production phase.	Nitrogen	290-298	pyruvate dehydrogenase E1 component	Escherichia coli str. K-12 substr. MG1655	102-106
2606106-7	1989	These results demonstrate that in an homozygous preparation of horse serotransferrin Tf 0, the heterogeneity is dependent, on the one hand, on the nature of the neuraminic acid substituting a N-acetyllactosaminic biantennary structure and, on the other hand, on the number of glycans bound to the polypeptide chain.	Nitrogen	192-193	serotransferrin	Equus caballus	69-84
2692561-2	1989	N-myristoyl glycinal diethylacetal (N-Myr-GOA) and other N-Myr-compounds (N-Myr-Gly-GOA, N-Myr-Gly-Gly-GOA and N-Myr-Gly-Gly-Gly-GOA) were newly synthesized and investigated for activity of antimyristoylation of these gag proteins and for influence on viral replication.	Nitrogen	0-1	Pr55(Gag)	Human immunodeficiency virus 1	218-221
2692561-6	1989	These results suggest that the N-myristoylation of p17 gag protein of HIV-1 may be essential in its structural assembly or maturation.	Nitrogen	31-32	Pr55(Gag)	Human immunodeficiency virus 1	55-58
2634737-1	1989	Effect of proportion of three branched-chain amino acids (leucine, valine, and isoleucine:BCAA) for nitrogen utilization was studied in vivo by an intragastric administration of 15N-L-leucine to control rats and liver-injured rats treated with carbon tetrachloride (CCl4-rats).	Nitrogen	100-108	AT-rich interaction domain 4B	Rattus norvegicus	90-94
2517477-7	1989	Milk biotinidase is O-glycosylated, whereas serum biotinidase is N-glycosylated.	Nitrogen	65-66	biotinidase	Homo sapiens	50-61
2693950-5	1989	The block in gene conversion in the pso3 homozygous diploid leads, in the case of nitrogen mustards, to specific repair intermediates which are lethal to the cells.	Nitrogen	82-90	ribonucleotide-diphosphate reductase subunit RNR4	Saccharomyces cerevisiae S288C	36-40
2472171-10	1989	The amino-acid sequence (mouse CD14), deduced from the nucleotide sequence of the MS7X insert consisted of 351 amino-acid residues with a high leucine content (17.66%) and five putative N-glycosylation sites, and in vitro translation predicted a protein of molecular mass of 37.5 kDa.	Nitrogen	186-187	CD14 antigen	Mus musculus	31-35
2610257-1	1989	Growth hormone administration affects growth in hypophysectomized animals by depressing urea synthesis and redistributing nitrogen into protein.	Nitrogen	122-130	gonadotropin releasing hormone receptor	Rattus norvegicus	0-14
2472171-11	1989	Human CD14 had 356 amino-acid residues, with high leucine content (15.5%), and contained four putative N-glycosylation sites.	Nitrogen	103-104	CD14 molecule	Homo sapiens	6-10
2477364-4	1989	Previous studies demonstrated different roles of each of the two alpha N-linked glycosylation sites (Asn-52 and Asn-78) in secretion of the uncombined subunit and the biologic activity of hCG dimer.	Nitrogen	71-72	chorionic gonadotropin subunit beta 5	Homo sapiens	188-191
2514793-8	1989	Together, these data support the notion (Wittwer et al., 1989) that N-glycosylation influences the fibrin-dependent catalytic activity of t-PA and that t-PA when expressed in different cell lines may consist of kinetically and structurally distinct glycoforms.	Nitrogen	68-69	plasminogen activator, tissue	Mus musculus	138-142
2610257-7	1989	In marked contrast, net glutamate uptake by the hypophysectomized rat liver, 71 +/- 15 nmol.min-1.100 g-1, was reversed by growth hormone administration to a striking net release rate of 960 +/- 229 nmol.min-1.100 g-1, suggesting that glutamine nitrogen is spared incorporation into urea by shunting into glutamate and release into the blood.	Nitrogen	245-253	gonadotropin releasing hormone receptor	Rattus norvegicus	123-137
2661018-2	1989	The predicted KAR2 protein sequence is most homologous to mammalian BiP/GRP78 and has several structural features in common with it: a functional secretory signal sequence, a yeast endoplasmic reticulum retention signal (HDEL) at the carboxyl terminus, and the absence of potential N-linked glycosylation sites.	Nitrogen	282-283	Hsp70 family ATPase KAR2	Saccharomyces cerevisiae S288C	14-18
2719965-4	1989	Chicken lipoprotein lipase differs from mammalian lipoprotein lipases with respect to the position of one N-glycosylation site and the presence of an additional 15-17 C-terminal amino acids.	Nitrogen	106-107	lipoprotein lipase	Gallus gallus	8-26
2608056-1	1989	The single site for N-linked glycosylation of the beta-subunit of bovine LH (LH beta) was disrupted by oligonucleotide-directed mutagenesis to assess its potential roles in the biosynthesis, transport, and hormonal activity of the LH alpha/beta heterodimer.	Nitrogen	20-21	lutropin subunit beta	Bos taurus	77-84
2750201-5	1989	LON is exclusively hydroxylated in the N-substituting aromatic ring, BRO is mainly N-deethylated in the urea moiety, and LIS and TER are both degraded into numerous metabolites.	Nitrogen	39-40	lon peptidase 1, mitochondrial	Rattus norvegicus	0-3
2475311-8	1989	Agp-1 and Agp-2 contain five and six potential N-glycosylation sites, respectively.	Nitrogen	47-48	anti gp70 immune complex 1	Mus musculus	0-5
2608056-7	1989	Both proteins displayed similar potency (ED50 = 32 vs. 41 ng/ml, respectively) and maximal stimulation of progesterone release Pmax = 2.7 vs 2.5 micrograms/ml), indicating that N-linked glycosylation of the LH beta-subunit does not play a significant role in LH signal transduction.	Nitrogen	177-178	lutropin subunit beta	Bos taurus	207-214
2608056-8	1989	Collectively, these results indicate that N-linked glycosylation is important for intracellular degradation of free LH beta, but is not essential for either its assembly with alpha-subunit or the transport and secretion of biologically active heterodimer.	Nitrogen	42-43	lutropin subunit beta	Bos taurus	116-123
2620292-5	1989	Choline and nitrogen mustard (HN2) share a plasma membrane carrier but the intracellular distribution of HN2 into DNA, RNA and protein, contrasts with that of choline, into phospholipid.	Nitrogen	12-20	MT-RNR2 like 2 (pseudogene)	Homo sapiens	30-33
2653828-1	1989	In Saccharomyces cerevisiae, the pathway of 4-aminobutyric acid catabolism, for use as a nitrogen source, involves a specific permease (encoded by the UGA4 gene) and two enzymes (encoded by the UGA1 and UGA2 genes, respectively).	Nitrogen	89-97	4-aminobutyrate transaminase	Saccharomyces cerevisiae S288C	194-198
2653828-1	1989	In Saccharomyces cerevisiae, the pathway of 4-aminobutyric acid catabolism, for use as a nitrogen source, involves a specific permease (encoded by the UGA4 gene) and two enzymes (encoded by the UGA1 and UGA2 genes, respectively).	Nitrogen	89-97	succinate-semialdehyde dehydrogenase (NAD(P)(+))	Saccharomyces cerevisiae S288C	203-207
2706086-6	1989	Only two out of 8 N-glycosylation sites in LAP and 3 in PAP are conserved, suggesting that the dense N-glycosylation of LAP is related to its function in lysosomes.	Nitrogen	18-19	acid phosphatase 2, lysosomal	Homo sapiens	43-46
2706086-6	1989	Only two out of 8 N-glycosylation sites in LAP and 3 in PAP are conserved, suggesting that the dense N-glycosylation of LAP is related to its function in lysosomes.	Nitrogen	18-19	acid phosphatase 2, lysosomal	Homo sapiens	120-123
2706086-6	1989	Only two out of 8 N-glycosylation sites in LAP and 3 in PAP are conserved, suggesting that the dense N-glycosylation of LAP is related to its function in lysosomes.	Nitrogen	101-102	acid phosphatase 2, lysosomal	Homo sapiens	43-46
2482345-4	1989	This study showed a significant correlation between the levels of serum IL-2R and disease activities, i.e., levels of urinary protein, blood urea nitrogen (BUN) and uric acid, in patients with IgA nephropathy.	Nitrogen	146-154	interleukin 2 receptor subunit alpha	Homo sapiens	72-77
3198605-4	1988	The major portions of both h-lamp-1 and h-lamp-2 reside on the luminal side of the lysosome and are heavily glycosylated by N-glycans: h-lamp-1 and h-lamp-2 were found to contain 19 and 16 potential N-glycosylation sites, respectively.	Nitrogen	124-125	lysosomal associated membrane protein 1	Homo sapiens	29-35
3198605-4	1988	The major portions of both h-lamp-1 and h-lamp-2 reside on the luminal side of the lysosome and are heavily glycosylated by N-glycans: h-lamp-1 and h-lamp-2 were found to contain 19 and 16 potential N-glycosylation sites, respectively.	Nitrogen	124-125	lysosomal associated membrane protein 1	Homo sapiens	137-143
3198605-8	1988	These N-glycosylation sites are clustered into two domains separated by a hinge-like structure enriched with proline and serine in h-lamp-1 or proline and threonine in h-lamp-2.	Nitrogen	6-7	lysosomal associated membrane protein 1	Homo sapiens	133-139
3060828-4	1988	We further studied the specific brain cell types: neurons, glial cells, and purified microvessel preparation, and demonstrated a heterogeneity in the N-linked glycosylation of the IR within an organ (brain).	Nitrogen	150-151	insulin receptor	Rattus norvegicus	180-182
2542939-8	1989	The mature ABP, composed of 163 residues with a molecular weight of 18,352, contains a potential N-glycosylation site (Asn-Thr-Thr), and the COOH-terminal tetrapeptide (Lys-Asp-Glu-Leu) may be a signal for retention of the ABP in the lumen of the endoplasmic reticulum.	Nitrogen	97-98	auxin-binding protein 4	Zea mays	11-14
20548671-2	1989	The design is based on electronic heterodyning of the CARS spectrum of nitrogen at two selected narrowband frequencies, ratioing the resulting signal strengths, and comparing this ratio with a theoretically derived temperature scale.	Nitrogen	71-79	cysteinyl-tRNA synthetase 1	Homo sapiens	54-58
2564698-3	1989	Moreover, in the presence of submicromolar concentrations of known chemosensitizers, such as N-acetylated sugars and mucin, these optima shift to 5, 15, 30, and 40 hertz, frequencies that correspond to the movements of swimming prey.	Nitrogen	93-94	LOC100508689	Homo sapiens	117-122
2706086-6	1989	Only two out of 8 N-glycosylation sites in LAP and 3 in PAP are conserved, suggesting that the dense N-glycosylation of LAP is related to its function in lysosomes.	Nitrogen	101-102	acid phosphatase 2, lysosomal	Homo sapiens	120-123
2620292-5	1989	Choline and nitrogen mustard (HN2) share a plasma membrane carrier but the intracellular distribution of HN2 into DNA, RNA and protein, contrasts with that of choline, into phospholipid.	Nitrogen	12-20	MT-RNR2 like 2 (pseudogene)	Homo sapiens	105-108
2784767-7	1989	Biochemical analysis of MLR3 antigen indicates that it is a phosphorylated protein with N-linked sugar moieties.	Nitrogen	88-89	CD69 molecule	Homo sapiens	24-28
3138915-7	1988	The results suggest that intramembranal calmodulin may participate in regulating PE N-methylation in skeletal muscle membranes, but it may not be responsible for the high N-methylation activity in diabetic rats.	Nitrogen	84-85	calmodulin 1	Rattus norvegicus	40-50
2689597-3	1989	The nuclear magnetic resonance spectroscopy shows that the mode of coordination of Zn(II) to LHRH consists of binding to the imidazole nitrogen and the peptide oxygen of the His-Trp bond.	Nitrogen	135-143	gonadotropin releasing hormone 1	Homo sapiens	93-97
3206560-4	1988	If the homogenate previously treated with liquid nitrogen was used as a source of enzyme, the specific activity of hepatic lipase was higher, namely, 13,000 and 19,000 microM of FFA/h per mg of protein in the presence or absence of heparin, respectively.	Nitrogen	49-57	hepatic triacylglycerol lipase	Oryctolagus cuniculus	115-129
3263433-5	1988	Studies of N-glycosylation patterns of one of these heterodimers suggested that it contained a rearranged V gamma 3/C gamma 1 gene product.	Nitrogen	11-12	T cell receptor gamma, variable 3	Mus musculus	106-125
2558927-3	1989	The antagonism of DGhCG against activation of adenylate cyclase and steroidogenesis was reversed, when WGA was bound to the N-linked carbohydrate moieties of hCG alpha- and beta-subunits followed by addition of purified Leydig cells.	Nitrogen	124-125	chorionic gonadotropin subunit beta 5	Homo sapiens	20-23
3138510-9	1988	BCAA-enriched TPN had a significant effect on nitrogen balance and survival rate in the septic phase model, and on muscle adenine nucleotide content in both models.	Nitrogen	46-54	AT-rich interaction domain 4B	Rattus norvegicus	0-4
3138510-11	1988	These results indicate that BCAA supplement in TPN improves nitrogen balance and peripheral cellular energy status and is thus clinically beneficial in preventive therapy for increased catabolism.	Nitrogen	60-68	AT-rich interaction domain 4B	Rattus norvegicus	28-32
3219355-0	1988	A structure of sperm whale myoglobin at a nitrogen gas pressure of 145 atmospheres.	Nitrogen	42-50	myoglobin	Physeter catodon	27-36
2586510-6	1989	It is shown that the Mg2+ and Ba2+ ions interact only with phosphate groups of DNA but Mn2+, Ni2+, Cu2+ ions interact also with the nitrogen bases of the macromolecule.	Nitrogen	132-140	mucin 7, secreted	Homo sapiens	21-24
3135628-9	1988	At 7 days, animals that received EGF or GLN had greater nitrogen retention.	Nitrogen	56-64	epidermal growth factor like 1	Rattus norvegicus	33-36
3041412-0	1988	Crosstalk between bacterial chemotaxis signal transduction proteins and regulators of transcription of the Ntr regulon: evidence that nitrogen assimilation and chemotaxis are controlled by a common phosphotransfer mechanism.	Nitrogen	134-142	neurotensin receptor 1	Homo sapiens	107-110
3041412-1	1988	We demonstrate by using purified bacterial components that the protein kinases that regulate chemotaxis and transcription of nitrogen-regulated genes, CheA and NRII, respectively, have cross-specificities: CheA can phosphorylate the Ntr transcription factor NRI and thereby activate transcription from the nitrogen-regulated glnA promoter, and NRII can phosphorylate CheY.	Nitrogen	125-133	neurotensin receptor 1	Homo sapiens	233-236
3041412-1	1988	We demonstrate by using purified bacterial components that the protein kinases that regulate chemotaxis and transcription of nitrogen-regulated genes, CheA and NRII, respectively, have cross-specificities: CheA can phosphorylate the Ntr transcription factor NRI and thereby activate transcription from the nitrogen-regulated glnA promoter, and NRII can phosphorylate CheY.	Nitrogen	306-314	neurotensin receptor 1	Homo sapiens	233-236
17792609-1	1988	Among the nitrogen (N(2))-fixing Cyanobacteria, the filamentous, nonheterocystous marine Oscillatoria spp.	Nitrogen	10-18	histocompatibility minor 13	Homo sapiens	102-105
2542268-9	1989	Two putative N-linked glycosylation sites are located in highly conserved domains in the center of the first and second segment of IRBP.	Nitrogen	13-14	retinol binding protein 3	Homo sapiens	131-135
17792609-1	1988	Among the nitrogen (N(2))-fixing Cyanobacteria, the filamentous, nonheterocystous marine Oscillatoria spp.	Nitrogen	20-25	histocompatibility minor 13	Homo sapiens	102-105
3390865-1	1988	An N-ethylmaleimide-sensitive transport component (NSF) has been purified on the basis of its ability to support transport between Golgi cisternae.	Nitrogen	3-4	N-ethylmaleimide sensitive factor, vesicle fusing ATPase	Homo sapiens	51-54
2968905-6	1988	Enzymatic digestion of IGF-I receptor beta subunit subtypes by glycopeptidase F resulted in similar molecular masses (84 kDa and 86 kDa) on SDS-PAGE, which suggests that the difference in molecular masses between two subtypes is attributable to the differences in N-linked complex-type carbohydrate chains on the extracellular domain of beta subunits.	Nitrogen	264-265	insulin-like growth factor 1	Mus musculus	23-28
2903023-4	1988	Different isozymes of cytochrome P-450 appear to be responsible for the N-demethylation of benzphetamine in lung as compared with nasal tissues.	Nitrogen	72-73	cytochrome P-450	Oryctolagus cuniculus	22-38
3072564-8	1988	In the crystal structure of insulin a hydrogen bond bridges the alpha-nitrogen of A21 with the backbone carbonyl of B23 glycine.	Nitrogen	70-78	insulin	Sus scrofa	28-35
3195134-2	1988	Freezing of chorion in liquid nitrogen enabled to find in the tissue labile neuraminidase, which occurred in soluble fraction as well as the more stable enzyme form, precipitated with cell particles.	Nitrogen	30-38	neuraminidase 1	Homo sapiens	76-89
3379943-15	1988	TNF infusion increased blood urea nitrogen and decreased serum bicarbonate compared to controls.	Nitrogen	34-42	tumor necrosis factor-like	Rattus norvegicus	0-3
2656668-6	1989	These results demonstrate that the intramitochondrial N-myristylation of the 52-kDa protein is not translationally linked.	Nitrogen	54-55	Sp110 nuclear body protein	Mus musculus	77-83
2967702-1	1988	The purpose of this study was to determine if structural analogs of dopamine in which the side chain nitrogen has been replaced by a permanently uncharged monomethylsulfide, monomethylselenide or sulfoxide group are capable of binding to the striatal D-2 dopamine receptor and acting as agonists at this receptor.	Nitrogen	101-109	dopamine receptor D2	Homo sapiens	251-272
2785120-8	1989	Compatible with these data was the finding that more prolonged infusions of recombinant TNF/cachectin and the combination with IL 1 increased urinary nitrogen excretion.	Nitrogen	150-158	tumor necrosis factor-like	Rattus norvegicus	88-91
2837530-3	1988	With Cu2+ the hormone has been shown to behave similarly to the thyrotropin releasing factor, forming a very stable [CuH-1L] complex involving coordination of three nitrogen donors: the Nim atom of the imidazole side chain and the two amido-N atoms of the pyroglutamylhistidyl unit.	Nitrogen	165-173	thyrotropin releasing hormone	Homo sapiens	64-92
2452157-8	1988	The predicted sequence of mature LACI contains 18 cysteines and three potential N-linked glycosylation sites.	Nitrogen	80-81	tissue factor pathway inhibitor	Homo sapiens	33-37
3049610-6	1988	Two-dimensional iodopeptide maps of 28kDa and HMW-28kDa were nearly identical; peptide-N-glycosidase digestion of purified HMW-28kDa demonstrated that it is the N-glycosylated form of 28kDa.	Nitrogen	87-88	cilia and flagella associated protein 97	Homo sapiens	123-126
3280136-7	1988	Starvation for nitrogen further induced (6- to 8-fold) transcription of IME1, but, as expected, the induction was found only in MATa/MAT alpha or rme1-1/rme1-1 diploids.	Nitrogen	15-23	transcription factor IME1	Saccharomyces cerevisiae S288C	72-76
3257775-3	1988	The predicted amino acid sequence of the putative mouse CD2 protein is consistent with that of a transmembrane glycoprotein, i.e., it consists of an N-terminal region of 186 amino acids bearing six potential N-glycosylation sites, a hydrophobic transmembrane segment of 25 residues, and a large cytoplasmic region of 116 amino acids rich in proline and basic residues.	Nitrogen	149-150	CD2 antigen	Mus musculus	56-59
2451665-3	1988	Preparations stored under these conditions at 2 degrees C in a nitrogen atmosphere retain significant Ca2+-stimulated ATPase activity for periods of 5-6 months or longer when assayed in the presence of asolectin.	Nitrogen	63-71	dynein axonemal heavy chain 8	Homo sapiens	118-124
2902084-6	1988	Although the ATPase contains one potential site of N-linked glycosylation, its electrophoretic mobility was unchanged following digestion with endoglycosidase H and it did not incorporate [3H]mannose or bind concanavalin A.	Nitrogen	51-52	AT695_RS06370	Staphylococcus aureus	13-19
2828116-3	1988	Unique features of rat chromogranin A are an eicosaglutamine sequence and two potential N-linked glycosylation sites.	Nitrogen	88-89	chromogranin A	Rattus norvegicus	23-37
3146461-3	1988	The C4A and C4B gene products differ in reactivity with C4A being more reactive with nitrogen nucleophiles, including hydralazine and isoniazid (drugs which induce SLE), than with oxygen nucleophiles.	Nitrogen	85-93	complement C4B (Chido blood group)	Homo sapiens	12-15
2971725-8	1988	On incubation with protease inhibitors, the Mr of IgE-binding factors (BF) is shifted from 25-27 to 37 kDa, indicating that IgE-BF are derived from the proteolytic cleavage of the 37-kDa molecule, previously identified as a membrane component of Fc epsilon R. On incubation with N-glycosylation inhibitors, the production of IgE-BF is significantly increased indicating that N-glycosylation inhibits the degradation of Fc epsilon R into IgE-BF.	Nitrogen	279-280	Fc epsilon receptor II	Homo sapiens	124-130
3173616-3	1988	Blood urea nitrogen was reduced by 32% (p = 0.001) with CA.RP.	Nitrogen	11-19	carbonic anhydrase 8	Homo sapiens	56-61
3121636-6	1987	vWF contains 17 potential N-linked glycosylation sites scattered throughout the molecule.	Nitrogen	26-27	von Willebrand factor	Cricetulus griseus	0-3
3681889-5	1987	This would be consistent with previous results that PNMT preferentially binds molecules with a more coplanar relationship between the aromatic ring and the amino nitrogen.	Nitrogen	162-170	phenylethanolamine N-methyltransferase	Homo sapiens	52-56
2971725-8	1988	On incubation with protease inhibitors, the Mr of IgE-binding factors (BF) is shifted from 25-27 to 37 kDa, indicating that IgE-BF are derived from the proteolytic cleavage of the 37-kDa molecule, previously identified as a membrane component of Fc epsilon R. On incubation with N-glycosylation inhibitors, the production of IgE-BF is significantly increased indicating that N-glycosylation inhibits the degradation of Fc epsilon R into IgE-BF.	Nitrogen	375-376	Fc epsilon receptor II	Homo sapiens	124-130
3681889-9	1987	Finally, although the aromatic ring binding region of the active site of PNMT contains a large degree of lipophilic character, only specific spatial orientations between the trifluoromethyl group and the amino nitrogen of aryl trifluoromethyl-substituted beta-phenylethylamines allow both to interact simultaneously in a manner that allows the amine to bind in a region of the active site in which methylation can occur.	Nitrogen	210-218	phenylethanolamine N-methyltransferase	Homo sapiens	73-77
3244370-2	1988	Addition of WPC up to 20% or SPC up to 4% to cow"s milk improved the consistency and flavour of the resultant zabadi and also increased its total solids, total protein, acidity, total volatile fatty acids and soluble nitrogen contents.	Nitrogen	217-225	surfactant protein C	Bos taurus	29-32
3131776-7	1988	Metabolic parameters were interpreted to indicate an anabolic response to GRF even though increases of 16% in nitrogen retention, 23% in plasma somatomedin C concentrations, and 36% in weight gain with pulsatile GRF treatment were variable and statistically similar to those of controls.	Nitrogen	110-118	growth hormone releasing hormone	Bos taurus	74-77
2961340-3	1987	The purpose of this study was to determine whether permanently charged structural analogs of dopamine containing either a nitrogen, sulfur, or selenium atom in the side chain can bind to and activate the D-2 dopamine receptor.	Nitrogen	122-130	dopamine receptor D2	Homo sapiens	204-225
2820951-13	1987	Cytochrome P-450 (pHP3) catalyzed N-demethylation of benzphetamine and aminopyrine and denitrification of 1-nitropropane.	Nitrogen	34-35	cytochrome P-450	Oryctolagus cuniculus	0-16
3356071-0	1988	In vitro induction of O6-methylguanine-DNA methyltransferase in C3H/10T1/2 cells by X-rays is inhibited by nitrogen.	Nitrogen	107-115	O-6-methylguanine-DNA methyltransferase	Mus musculus	22-60
20454081-1	1987	The noise level in single-pulse resonant nitrogen CARS spectra is shown to decrease with increasing pump laser bandwidth.	Nitrogen	41-49	cysteinyl-tRNA synthetase 1	Homo sapiens	50-54
3384397-2	1988	This protein migrates Mr 45,000-70,000 dalton region with a broad singlet or doublet on SDS-PAGE, specifically binds to C3b and C4b, has an acidic pI around pH 4, is rich in proline in amino acid analysis, possesses both N-linked and O-linked oligosaccharides, generates iC3b by acting as a cofactor for I-mediated C3b cleavage, and does not disassemble the C3 convertases.	Nitrogen	221-222	complement C4B (Chido blood group)	Homo sapiens	128-131
3615491-2	1987	We report here, further evaluation of nitrogen mustard (HN2), for possible use in the extracorporeal therapy of sickle cell anemia.	Nitrogen	38-46	MT-RNR2 like 2 (pseudogene)	Homo sapiens	56-59
2826035-3	1988	In comparison with control cells that were transfected with the parent vector, the ATase-expressing clones were considerably more resistant to the toxic effects of the methylating agents N-methyl-N-nitrosourea and methylmethanesulphonate or the chloroethylating agents Mz or taurine chloroethylnitrosourea, but unchanged in their susceptibility to the bis-chloroethylating agent nitrogen mustard.	Nitrogen	379-387	O-6-methylguanine-DNA methyltransferase	Mus musculus	83-88
3709076-3	1986	Absorption of total nitrogen and of 14 amino acid residues occurred to a significantly greater extent from the low molecular weight LH1 than from the higher molecular weight LH2.	Nitrogen	20-28	LIM homeobox 2	Homo sapiens	174-177
3664462-1	1987	Monoclonal antibody (MAb) F7-26 generated against nitrogen mustard (HN2)-treated DNA (O.S.	Nitrogen	50-58	MT-RNR2 like 2 (pseudogene)	Homo sapiens	68-71
2981876-3	1985	There are two N-linked glycosylated intermediate precursor forms (apparent Mr = 35,000 (p35) and 37,000 (p37].	Nitrogen	14-15	nucleoporin 37	Homo sapiens	105-108
3119252-5	1987	The fluorescent complex formed on the solid-phase [monoclonal antibody-hCG-monoclonal antibody-biotin-streptavidin-BCPDA-Eu3+] is measured by excitation at 337.1 nm with a nitrogen laser and monitoring the emission at 615 nm in a specially designed gated fluorometer working in a time-resolved mode.	Nitrogen	172-180	hypertrichosis 2 (generalised, congenital)	Homo sapiens	71-74
2861268-11	1985	N-696 treatments showed a tendency to decrease plasma renin concentration (PRC) in SHR and DOC rats, whereas PPL treatments significantly decreased PRC in these hypertensive rats.	Nitrogen	0-1	renin	Rattus norvegicus	54-59
3329127-21	1987	The improved N balance obtained by enhancing dietary non-protein energy (carbohydrate, fat) can be brought on by reducing amino acid oxidation and slightly increasing protein synthesis.	Nitrogen	13-14	FAT atypical cadherin 1	Homo sapiens	87-90
6531301-0	1984	A study of the effect of chronic applications of nitrogen mustard (HN2) on acute responses of mammalian skin to UVB irradiation in vivo.	Nitrogen	49-57	MT-RNR2 like 2 (pseudogene)	Homo sapiens	67-70
2446730-3	1987	Several predicted features of gB2 are consistent with a membrane-bound glycoprotein, i.e., a signal peptide sequence, a hydrophilic extracellular domain containing possible N-linked glycosylation sites, a hydrophobic membrane spanning sequence, and a cytoplasmic domain.	Nitrogen	173-174	gamma-aminobutyric acid type B receptor subunit 2	Homo sapiens	30-33
6205199-9	1984	The elevated serum urea nitrogen at 4 hr after the Cd2+ challenge was reduced by pretreatment 6 to 24 hr prior to the challenge dose.	Nitrogen	24-32	CD2 antigen	Mus musculus	51-54
3477663-7	1987	Nitrogen mustard [(HN2) NCS-762] and x-rays were selectively toxic to P388/R cells.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	19-22
6662859-1	1983	Cell survival has been measured in normal and Fanconi"s anaemia (FA) human fibroblasts after treatment with the bifunctional alkylating agent, nitrogen mustard (HN2).	Nitrogen	143-151	MT-RNR2 like 2 (pseudogene)	Homo sapiens	161-164
6343842-1	1983	The activities of the proline-specific permease (PUT4) and the general amino acid permease (GAP1) of Saccharomyces cerevisiae vary 70- to 140-fold in response to the nitrogen source of the growth medium.	Nitrogen	166-174	proline permease PUT4	Saccharomyces cerevisiae S288C	49-53
3117057-1	1987	The ability of a high affinity, N-chloroethyl derivative to irreversibly occupy dopamine receptors has been used to probe the nature of the interaction of the bovine anterior pituitary D2-dopamine receptor with a putative G-protein.	Nitrogen	32-33	dopamine receptor D2	Bos taurus	185-205
6829569-1	1983	Nitrogen mustard (HN-2) is an alkylating agent known to be effective in inducing and prolonging remissions of nephrotic syndrome in children.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	18-22
3624248-9	1987	alpha 2----3-Linked sialic acid and N-acetyllactosaminyl repeats are selectively present in the side chains attached to C-6 and C-2 of 2,6-substituted alpha-mannose and C-4 of 2,4-substituted alpha-mannose.	Nitrogen	36-37	complement C6	Homo sapiens	120-123
6830337-1	1983	Hepatic-Aid is purported to ameliorate encephalopathy and promote positive nitrogen balance in protein-intolerant, cirrhotic patients by correcting their imbalanced amino acid profile.	Nitrogen	75-83	activation induced cytidine deaminase	Homo sapiens	8-11
3111484-4	1987	We also reported a decrease of both liver cytochrome P-450 content and microsomal cytochrome P-450b dependent N-demethylation activities.	Nitrogen	110-111	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	82-99
6822531-8	1983	A complex of this form with P-450scc produced a 422 nm Soret absorption maximum as found for the parent compound, indicating nitrogen coordination to the heme iron.	Nitrogen	125-133	cholesterol side-chain cleavage enzyme, mitochondrial	Bos taurus	28-36
3312952-4	1987	The RAD4 and RAD14 genes have a particular role in repair following exposure to those ethylating agents that preferentially alkylate oxygen, but not to those that preferentially ethylate nitrogen.	Nitrogen	187-195	Rad4p	Saccharomyces cerevisiae S288C	4-8
6684324-0	1983	[Effect of increased amount of soy bean protein in the diet on the development and nitrogen metabolism of 2 generations of rats.	Nitrogen	83-91	brain expressed, associated with NEDD4, 1	Rattus norvegicus	35-39
7127291-2	1982	Thus, nitrogen mustard [methylbis(beta-chloroethyl)amine] (HN2) at 0.5 microM decreased cell viability by only a few percent in the absence of caffeine.	Nitrogen	6-14	MT-RNR2 like 2 (pseudogene)	Homo sapiens	59-62
3302672-9	1987	The deduced FUS1 protein sequence exhibits a striking concentration of serines and threonines at the amino terminus (46%; 33 of 71), followed by a 25-amino acid hydrophobic stretch and a predominantly hydrophilic carboxy terminus, which contains several potential N-glycosylation sites (Asn-X-Ser/Thr).	Nitrogen	264-265	Fus1p	Saccharomyces cerevisiae S288C	12-16
6286643-5	1982	The results of these studies are consistent with a model for the N- and O-glycosylation of hCG in which 1) N-glycosylation of hCG occurs co-translationally or very shortly after translation, and 2) the addition of O-linked GalNAc residues to the polypeptide and the addition of peripheral GlcNAc residues to the N-linked oligosaccharide chains occur just prior to secretion, presumably in the Golgi complex.	Nitrogen	65-66	chorionic gonadotropin subunit beta 5	Homo sapiens	91-94
6286643-5	1982	The results of these studies are consistent with a model for the N- and O-glycosylation of hCG in which 1) N-glycosylation of hCG occurs co-translationally or very shortly after translation, and 2) the addition of O-linked GalNAc residues to the polypeptide and the addition of peripheral GlcNAc residues to the N-linked oligosaccharide chains occur just prior to secretion, presumably in the Golgi complex.	Nitrogen	107-108	chorionic gonadotropin subunit beta 5	Homo sapiens	91-94
6286643-5	1982	The results of these studies are consistent with a model for the N- and O-glycosylation of hCG in which 1) N-glycosylation of hCG occurs co-translationally or very shortly after translation, and 2) the addition of O-linked GalNAc residues to the polypeptide and the addition of peripheral GlcNAc residues to the N-linked oligosaccharide chains occur just prior to secretion, presumably in the Golgi complex.	Nitrogen	107-108	chorionic gonadotropin subunit beta 5	Homo sapiens	126-129
6288370-9	1982	For type I, of the analogs tested the most efficacious for stimulating [3H]cIMP binding were those containing a nitrogen atom attached to C-8, 8-aminobutylamino-cAMP being the most effective.	Nitrogen	112-120	homeobox C8	Homo sapiens	138-141
6953438-3	1982	Our results show that caffeine potentiates the lethality of the nitrogen mustard 2-chloro-N-(2-chloroethyl)-N-methylethanamine (HN2) by inducing damaged cells to undergo mitosis before properly repairing lesions in their DNA.	Nitrogen	64-72	MT-RNR2 like 2 (pseudogene)	Homo sapiens	128-131
3302675-7	1987	Cells carrying the ypt1-1 mutation died upon nitrogen starvation even at a temperature permissive for growth; diploid cells homozygous for ypt1-1 did not sporulate.	Nitrogen	45-53	Rab family GTPase YPT11	Saccharomyces cerevisiae S288C	19-25
3035382-2	1987	At least two specific DNA rearrangements involving the nitrogen-fixation (nif) genes occur during heterocyst differentiation, one within the nifD gene and the other near the nifS gene.	Nitrogen	55-63	NFS1 cysteine desulfurase	Homo sapiens	174-178
6279163-5	1982	(1) Both AN1 and AN2 increased as the basicity of the nitrogen atom of the fifth ligand increased, while AN1 increased concomitant with the decrease of AN2 by steric hindrance of the fifth ligand.	Nitrogen	54-62	elongator acetyltransferase complex subunit 4	Homo sapiens	17-20
6279163-6	1982	(2) Both AN1 and AN2 increased as the basicity of the porphyrin nitrogen atom decreased.	Nitrogen	64-72	elongator acetyltransferase complex subunit 4	Homo sapiens	17-20
6270345-5	1981	In addition, these studies indicate that some of the N-tropic recombinants have experienced recombination within the p30 gene.	Nitrogen	53-54	high mobility group box 1	Mus musculus	117-120
3580021-1	1987	Aldehyde dehydrogenases (ALDH) isolated from livers of adult female SPF Sprague-Dawley rats were rapidly (within hours) inactivated by oxygen (7.8 ppm, from air) and simultaneous exposure to light energy (subdued daylight, 5000 lx; direct sunlight, 66,000 lx) at 22 degrees C. Oxygen withdrawal (e.g. by treatment with nitrogen) and darkness prevented the inactivation.	Nitrogen	319-327	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	0-23
7291041-7	1981	Rates of cleavage of hexa- and heptapeptide accord with those found for synthetic N-protected dipeptide substrates.	Nitrogen	82-83	hexosaminidase subunit alpha	Rattus norvegicus	21-25
3580021-1	1987	Aldehyde dehydrogenases (ALDH) isolated from livers of adult female SPF Sprague-Dawley rats were rapidly (within hours) inactivated by oxygen (7.8 ppm, from air) and simultaneous exposure to light energy (subdued daylight, 5000 lx; direct sunlight, 66,000 lx) at 22 degrees C. Oxygen withdrawal (e.g. by treatment with nitrogen) and darkness prevented the inactivation.	Nitrogen	319-327	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	25-29
3791235-1	1987	A linear increase in cell uptake of nitrogen mustard, methyl-bis(beta-chloroethyl)amine (HN2), between 1 and 5 min, was observed after in vitro incubation of Ehrlich ascites tumor cells at 37 degrees C in phosphate-buffered saline containing HN2 followed by washing in 0 degrees C phosphate-buffered saline.	Nitrogen	36-44	MT-RNR2 like 2 (pseudogene)	Homo sapiens	89-92
7265116-2	1981	An examination of the formation of cytochrome P-450 metabolic intermediate complexes with these species suggests that N-oxidation of the pharmacologically active (R)-amine in inhibited by the S enantiomer.	Nitrogen	118-119	cytochrome P-450	Oryctolagus cuniculus	35-51
3330992-6	1987	For N, but not H, there was a positive correlation between age and the magnitude in reduction of SBP (r = 0.79; p less than 0.005), but not for DPB.	Nitrogen	4-5	selenium binding protein 1	Homo sapiens	97-100
2824773-1	1987	N-Substituted analogues of trans-7- and trans-9-hydroxy-1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinoline (trans-7- and trans-9-OH-OHBQ) were tested for dopamine (DA) D2 receptor affinity by using in vitro [3H]spiperone and in vivo 5,6-di-n-Pr-ADTN binding assays.	Nitrogen	0-1	dopamine receptor D2	Homo sapiens	149-174
3791235-1	1987	A linear increase in cell uptake of nitrogen mustard, methyl-bis(beta-chloroethyl)amine (HN2), between 1 and 5 min, was observed after in vitro incubation of Ehrlich ascites tumor cells at 37 degrees C in phosphate-buffered saline containing HN2 followed by washing in 0 degrees C phosphate-buffered saline.	Nitrogen	36-44	MT-RNR2 like 2 (pseudogene)	Homo sapiens	242-245
2432837-11	1986	Additionally, hydroxylamine cleavage of an Asn-Gly bond in prefetuin localized one of the N-linked carbohydrate side chains to the middle of the polypeptide chain of native fetuin.	Nitrogen	90-91	alpha-2-HS-glycoprotein	Oryctolagus cuniculus	62-68
3663229-9	1987	The direct involvement of cytochrome P-450 in this reaction is supported by the observation that the presence of inhibitors of cytochrome P-450, in particular of carbon monoxide, markedly decreased the rate of N-demethylation.	Nitrogen	210-211	cytochrome P-450	Oryctolagus cuniculus	26-42
3663229-9	1987	The direct involvement of cytochrome P-450 in this reaction is supported by the observation that the presence of inhibitors of cytochrome P-450, in particular of carbon monoxide, markedly decreased the rate of N-demethylation.	Nitrogen	210-211	cytochrome P-450	Oryctolagus cuniculus	127-143
7005220-1	1981	Lysine 372 of N-ethylmaleimide actin was specifically (60%) labeled by 7-chloro-4-nitrobenzeno-2-oxa-1,3-diazole chloride (NBD-Cl), which also reacted with lysines on cyanogen bromide fragment 17 (20%) and other undetermined residues (20%).	Nitrogen	14-15	OXA1L mitochondrial inner membrane protein	Homo sapiens	97-102
6162639-3	1981	N-Glycosidically linked glycans from unfractionated alpha 1-fetoprotein were isolated and chemically characterized.	Nitrogen	0-1	alpha-fetoprotein	Rattus norvegicus	52-71
3806237-7	1986	Endogenous nitrogen excretion of rats on bean diets was estimated by the ratio of total endogenous N to marker N, based on the protein-free diet.	Nitrogen	11-19	brain expressed, associated with NEDD4, 1	Rattus norvegicus	41-45
6270289-6	1981	However, in the rats fed on the 30% carbohydrate-50% fat diet, the urinary excretion of nitrogen and urea were reduced in both groups and these findings were reflected in the reduced serum urea level.	Nitrogen	88-96	FAT atypical cadherin 1	Rattus norvegicus	53-56
2957958-2	1987	Nitrous acid degradation studies revealed significant differences in the distribution of N-sulfate and N-acetyl groups in heparan sulfate present in the PC12 cell-soluble fraction, membranes, and medium and demonstrated that NGF treatment led to an increased proportion of N-sulfated segments in the cell-associated heparan sulfate, although no such change was seen in that released into the culture medium.	Nitrogen	0-1	nerve growth factor	Rattus norvegicus	225-228
2957958-2	1987	Nitrous acid degradation studies revealed significant differences in the distribution of N-sulfate and N-acetyl groups in heparan sulfate present in the PC12 cell-soluble fraction, membranes, and medium and demonstrated that NGF treatment led to an increased proportion of N-sulfated segments in the cell-associated heparan sulfate, although no such change was seen in that released into the culture medium.	Nitrogen	89-90	nerve growth factor	Rattus norvegicus	225-228
3109485-4	1987	The NADH- and NADPH-supported pathway of N-oxidation in the cytochrome b5-supplemented microsomal fractions thus probably involves distinct forms of cytochrome P-450.	Nitrogen	4-5	cytochrome P-450	Oryctolagus cuniculus	149-165
3558366-11	1987	The structural data indicate the presence of at least two sialyltransferases in human cervical epithelium and further suggest a potential physiologically significant competition between sialyltransferase and beta-N-acetylglucosaminyltransferase for C-6 of the N-acetylgalactosamine residue O-glycosidically linked to serine/threonine of the polypeptide core.	Nitrogen	213-214	complement C6	Homo sapiens	249-252
6157960-3	1980	In a fluorimetric assay, this derivative competitively inhibited the reaction between purified hog renin and a synthetic N-acetyl-tetradecapeptide renin substrate with a Ki of the same order of magnitude as that of pepstatin.	Nitrogen	121-122	renin	Rattus norvegicus	99-104
6157960-3	1980	In a fluorimetric assay, this derivative competitively inhibited the reaction between purified hog renin and a synthetic N-acetyl-tetradecapeptide renin substrate with a Ki of the same order of magnitude as that of pepstatin.	Nitrogen	121-122	renin	Rattus norvegicus	147-152
3806237-8	1986	The results indicated that rats fed bean-containing diets excreted significantly more endogenous nitrogen than those fed the casein diet, even though the casein diet had stimulated twice as much endogenous excretion than the protein-free diet.	Nitrogen	97-105	brain expressed, associated with NEDD4, 1	Rattus norvegicus	36-40
6104674-2	1980	N,N-Dimethyl diethyl, dipropyl, dibutyl, and N-monoisopropylaminoaphthylenesulfonyl derivatives of melanotropin inhibiting factor (MIF) and its metabolites were prepared, and their chromatographic behavior was investigated with thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC), using five solvent systems on polyamide layers and ten solvent systems on muBondapak C18 and muBondapak phenyl columns.	Nitrogen	0-1	macrophage migration inhibitory factor	Homo sapiens	99-129
6104674-2	1980	N,N-Dimethyl diethyl, dipropyl, dibutyl, and N-monoisopropylaminoaphthylenesulfonyl derivatives of melanotropin inhibiting factor (MIF) and its metabolites were prepared, and their chromatographic behavior was investigated with thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC), using five solvent systems on polyamide layers and ten solvent systems on muBondapak C18 and muBondapak phenyl columns.	Nitrogen	0-1	macrophage migration inhibitory factor	Homo sapiens	131-134
2943981-3	1986	In the present series, the dopamine D2-receptor agonists have the S-configuration at the nitrogen-bearing carbon (C2), whereas the only established D2-receptor antagonist, 1S,2R-5-hydroxyl-1-methyl-2-(di-n-propylamino)tetralin (1S,2R-UH-242), has the opposite absolute configuration at C2.	Nitrogen	89-97	dopamine receptor D2	Homo sapiens	27-47
6966310-10	1980	In addition, we demonstrate that the IgG3 component of the response to TI-1 antigens is virtually absent in mice expressing the CBA/N phenotype, which supports our previous finding that the CBA/N defect may be restricted to a B-lymphocyte subpopulation containing most of the precursors of IgG3-secreting cells.	Nitrogen	132-133	Immunoglobulin heavy constant gamma 3	Mus musculus	37-41
3822822-10	1987	The properties of the photoproduct are consistent with it being generated by the hydrolytic fission of an azetidine photoadduct in which the N(7) and C(8) atoms of the 5"-adenine in d(ApA) are linked respectively to the C(6) and C(5) positions of the 3"-adenine.	Nitrogen	141-142	glutamyl aminopeptidase	Homo sapiens	184-187
3101728-2	1987	G6PD promoted H+ production was quantified under atmospheres of N2 and O2 in frozen sections from rat mammary tissue in the presence and absence of a H+ acceptor (Total H+ and Type I H+).	Nitrogen	64-66	glucose-6-phosphate dehydrogenase	Rattus norvegicus	0-4
3091344-8	1986	Currently, the authors are exploiting BuPdGTP, BuPdGDP, and similar butylanilino derivatives of dATP to probe the active site of pol alpha and to develop other N2-substituted analogues which can bind selectively to the substrate sites of other important polymerases and nucleotide binding proteins.	Nitrogen	160-162	DNA polymerase alpha 1, catalytic subunit	Homo sapiens	129-138
24435693-4	1987	Increase in nitrogen levels, in general, brought about a significant increase over the control (zero-nitrogen) in(14)CO2 assimilation, RuBPC, PEPC activities and DM production.	Nitrogen	12-20	phosphoenolpyruvate carboxylase 2	Triticum aestivum	142-146
6153466-2	1980	The p-n-butyl derivative (BuAU) was found to inhibit DNA polymerase alpha with a Ki of approximately 60 microM.	Nitrogen	6-7	DNA polymerase alpha 1, catalytic subunit	Homo sapiens	53-73
3758464-5	1986	Participation of P-450b/e in BPh N-demethylation was notably lower in the neonates in comparison to the adult rats.	Nitrogen	33-34	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	17-23
311819-2	1979	Here we demonstrate that mice, with the CBA/N phenotype have perferential deficiencies of IgM and IgG3 immunoglobulin expression, both when measured in serum and in cells secreting these isotypes, and that this deficiency is only partially corrected by polyclonal activation of B cells.	Nitrogen	44-45	Immunoglobulin heavy constant gamma 3	Mus musculus	98-102
3575228-5	1987	True metabolizable energy (TME) and nitrogen-corrected TME (TMEn) values of HO1 corn were determined using adult roosters.	Nitrogen	36-44	heme oxygenase 1	Gallus gallus	76-79
4063335-4	1985	Duodenal non-ammonia-N flow (g/d) was increased more by FM (8.0) than by GNM (5.9) and SBM (5.8), whilst microbial N flow (g/d) was increased more by SBM (3.9) than by GNM (2.3) and FM (1.6).	Nitrogen	21-22	dystrophin	Ovis aries	3-4
698922-1	1978	Multicellular tumor spheroids (MTS) have been exposed to chemotherapeutic agents in vitro (nitrogen mustard) or in vivo (cyclophosphamide) and analyzed in vitro in terms of altered growth patterns.	Nitrogen	91-99	MLRL	Homo sapiens	0-29
3021451-5	1986	Culturing the cells in the presence of varying concentrations of tunicamycin, an inhibitor of N-glycosylation, revealed six species of 5"-nucleotidase after sodium dodecyl sulfate/polyacrylamide electrophoresis.	Nitrogen	94-95	5' nucleotidase, ecto	Rattus norvegicus	135-150
4063335-4	1985	Duodenal non-ammonia-N flow (g/d) was increased more by FM (8.0) than by GNM (5.9) and SBM (5.8), whilst microbial N flow (g/d) was increased more by SBM (3.9) than by GNM (2.3) and FM (1.6).	Nitrogen	21-22	dystrophin	Ovis aries	31-32
19605248-6	1978	A product LPH 1-77 was tentatively identified based in part on its mobility on slab gels as compared to beta-LPH and beta-endophine and by N-group determination of cleavage products.	Nitrogen	139-140	lactase	Homo sapiens	10-15
4063335-7	1985	The irreversible loss of ammonia in the forestomachs (g N/d) was increased more by SBM (11.9) than by GNM (7.2) and FM (5.8), whilst ammonia outflow from the rumen (g N/d) was increased to a similar extent by all supplements (1.1, 0.9 and 0.8 respectively), as was the amount of microbial N (g/d) synthesized from sources other than rumen ammonia (1.8, 2.0 and 1.9 respectively).	Nitrogen	56-57	dystrophin	Ovis aries	58-59
4063335-7	1985	The irreversible loss of ammonia in the forestomachs (g N/d) was increased more by SBM (11.9) than by GNM (7.2) and FM (5.8), whilst ammonia outflow from the rumen (g N/d) was increased to a similar extent by all supplements (1.1, 0.9 and 0.8 respectively), as was the amount of microbial N (g/d) synthesized from sources other than rumen ammonia (1.8, 2.0 and 1.9 respectively).	Nitrogen	56-57	dystrophin	Ovis aries	73-74
27521-1	1978	Myoglobin(IV), the derivative of myoglobin at the formal oxidation state IV, prepared from kangaroo (Megaleia rufa), horse, or sperm whale myoglobin, when cooled to liquid nitrogen temperature, assumes acid and alkaline forms with different optical spectra.	Nitrogen	172-180	myoglobin	Physeter catodon	0-9
27521-7	1978	The acid forms of myoglobin(IV) are conveniently prepared by cooling solutions in borate buffers, initially pH 8.3, to liquid nitrogen temperature.	Nitrogen	126-134	myoglobin	Physeter catodon	18-27
3806256-0	1986	The influence of rat endogenous nitrogen excretion on the assessment of bean protein quality.	Nitrogen	32-40	brain expressed, associated with NEDD4, 1	Rattus norvegicus	72-76
3806256-1	1986	The main objective of the present work was to study the interference of rat endogenous nitrogen excretion with the assessment of digestibility and biological value of dry bean (Phaseolus vulgaris, L.) protein.	Nitrogen	87-95	brain expressed, associated with NEDD4, 1	Rattus norvegicus	171-175
3806256-3	1986	Nitrogen balance studies indicated that bean protein digestibility and biological value were higher when N-balance was based on 15N-excess as compared to total nitrogen, both for undenaturated and heat-denaturated protein.	Nitrogen	0-8	brain expressed, associated with NEDD4, 1	Rattus norvegicus	40-44
3806256-5	1986	The results permitted the conclusion that the conventional methods employed for calculation of bean protein digestibility and biological value, based on total nitrogen balance and protein-free diet, underestimate these indices of protein quality.	Nitrogen	159-167	brain expressed, associated with NEDD4, 1	Rattus norvegicus	95-99
3089784-1	1986	N-Glycosidically linked glycopeptides released by mild alkaline treatment of human factor VIII/von Willebrand factor (FVIII/vWF) were fractionated by serial affinity chromatography on columns of Sepharose linked to concanavalin A (ConA) and Lens culinaris agglutinin (LCA).	Nitrogen	0-1	coagulation factor VIII	Homo sapiens	118-123
4063335-7	1985	The irreversible loss of ammonia in the forestomachs (g N/d) was increased more by SBM (11.9) than by GNM (7.2) and FM (5.8), whilst ammonia outflow from the rumen (g N/d) was increased to a similar extent by all supplements (1.1, 0.9 and 0.8 respectively), as was the amount of microbial N (g/d) synthesized from sources other than rumen ammonia (1.8, 2.0 and 1.9 respectively).	Nitrogen	56-57	dystrophin	Ovis aries	73-74
565677-2	1978	Since differences in rates of formation and repair of cross-links may explain differences in activity of these agents, we have studied these events following exposure of L1210 cells to nitrogen mustard (HN2) and melphalan.	Nitrogen	185-193	MT-RNR2 like 2 (pseudogene)	Homo sapiens	203-206
16663684-0	1984	Partitioning of Nitrogen among Ribulose-1,5-bisphosphate Carboxylase/Oxygenase, Phosphoenolpyruvate Carboxylase, and Pyruvate Orthophosphate Dikinase as Related to Biomass Productivity in Maize Seedlings.	Nitrogen	16-24	pyruvate, phosphate dikinase 1, chloroplastic	Zea mays	117-149
629928-0	1978	Fat-free body mass from skinfold thickness: a close relationship with total body nitrogen.	Nitrogen	81-89	FAT atypical cadherin 1	Homo sapiens	0-3
3028048-8	1986	From these results the principal physiological function of the cytosol 5"-nucleotidase is assumed to be dephosphorylation of IMP as the first step in the pathway of uric acid formation from IMP, which is important in the elimination of nitrogen of amino acids and proteins in a uricotelic animal.	Nitrogen	236-244	5'-nucleotidase ecto	Gallus gallus	71-86
6142738-6	1984	It is assumed that the renal cortex contains n-cholinoreactive systems that have a direct or mediated action on renin secretion and m-cholinoreactive systems that modulate the activity of the former systems.	Nitrogen	25-26	renin	Rattus norvegicus	112-117
4035563-7	1985	The Hepatic-Aid diet increased (p less than 0.05) nitrogen and carbon fluxes significantly more than did the standard diet.	Nitrogen	50-58	activation induced cytidine deaminase	Homo sapiens	12-15
629928-2	1978	Fat-free mass has been determined from the simple measurement of skinfold thickness and it has been demonstrated that there is a close correlation with total body nitrogen even though the test subjects had a wide range of nutritional status.	Nitrogen	163-171	FAT atypical cadherin 1	Homo sapiens	0-3
6714940-0	1984	Structural studies on O- and N-glycosidically linked carbohydrate chains on Collocalia mucin.	Nitrogen	29-30	LOC100508689	Homo sapiens	87-92
17751-1	1977	In the histamine H2-receptor antagonist metiamide (2a) isosteric replacement of thione sulfur (=S) by carbonyl oxygen (=O) or imino nitrogen (=NH) affords the urea 2c and guanidine 2d which are antagonists of decreased potency.	Nitrogen	132-140	histamine receptor H2	Homo sapiens	7-28
407361-4	1977	Plots of log Cth against the number of carbon atoms, n, in n-alcohols, n-aldehydes and n-fatty acids showed linear relationships as represented by long Cth=-An+B.	Nitrogen	21-22	V-set and immunoglobulin domain containing 2	Homo sapiens	13-16
407361-4	1977	Plots of log Cth against the number of carbon atoms, n, in n-alcohols, n-aldehydes and n-fatty acids showed linear relationships as represented by long Cth=-An+B.	Nitrogen	21-22	V-set and immunoglobulin domain containing 2	Homo sapiens	152-155
3921525-1	1985	In contrast to wild-type strains of the yeast Saccharomyces cerevisiae, lys2 and lys5 mutants are able to utilize alpha-aminoadipate as a primary source of nitrogen.	Nitrogen	156-164	L-aminoadipate-semialdehyde dehydrogenase	Saccharomyces cerevisiae S288C	72-76
3921525-1	1985	In contrast to wild-type strains of the yeast Saccharomyces cerevisiae, lys2 and lys5 mutants are able to utilize alpha-aminoadipate as a primary source of nitrogen.	Nitrogen	156-164	holo-[acyl-carrier-protein] synthase	Saccharomyces cerevisiae S288C	81-85
16664208-5	1985	An early increase in root nodule fresh weight and AR activity was also observed in response to this treatment and was followed similarly by early decline.The addition of high levels of soil-applied nitrogen increased leaf NR activity and delayed late season decline in NR activity for both control and early reproductive plants.	Nitrogen	198-206	inducible nitrate reductase [NADH] 1	Glycine max	222-224
16664208-5	1985	An early increase in root nodule fresh weight and AR activity was also observed in response to this treatment and was followed similarly by early decline.The addition of high levels of soil-applied nitrogen increased leaf NR activity and delayed late season decline in NR activity for both control and early reproductive plants.	Nitrogen	198-206	inducible nitrate reductase [NADH] 1	Glycine max	269-271
16664208-7	1985	A limited additional increase in leaf NR activity was observed in response to light enhancement plus soil-applied nitrogen.	Nitrogen	114-122	inducible nitrate reductase [NADH] 1	Glycine max	38-40
402892-0	1977	Effect of carbohydrate and fat intake on nitrogen excretion during total intravenous feeding.	Nitrogen	41-49	FAT atypical cadherin 1	Homo sapiens	27-30
6418691-5	1983	The nitrogen absorption and digestibility of the amino acid mixtures offered to Gp I and Gp II was significantly higher than that of the controls.	Nitrogen	4-12	glucose-6-phosphate isomerase	Homo sapiens	80-94
860978-4	1977	Earlier studies (8) showed that exposure to 13.8 atm nitrogen under normoxic conditions reduced running activity by 10%.	Nitrogen	53-61	ataxia telangiectasia mutated	Mus musculus	49-52
6410971-9	1983	After TRH in group A, the mean (+/- SE) Pdct increased by 10 +/- 3 cm H2O (p less than 0.05) in study I and by 10 +/- 3 cm H2O (p less than 0.05) in study II whereas the mean compliance decreased by 37 +/- 20 ml/cm H2O (NS) in study I and by 44 +/- 18 ml/cm H2O (p less than 0.05) in study II.	Nitrogen	220-222	thyrotropin releasing hormone	Homo sapiens	6-9
860978-6	1977	Visual observations of social behavior and respiratory distress suggest that a nitrogen tension of 13.8 atm does not provide protection against oxygen toxicity.	Nitrogen	79-87	ataxia telangiectasia mutated	Mus musculus	104-107
883159-4	1977	But the values of the dissociation constants of the intermediary complexes for both MAO types differed dramatically with alterations of the substituents at the nitrogen atom in molecules of the 2-propynylamine derivatives which probably determines the well recognized properties of the 2-propynylamine derivatives of causing highly selective inhibition of oxidative deamination of various biogenic monoamines.	Nitrogen	160-168	monoamine oxidase A	Rattus norvegicus	84-87
139671-2	1977	Their action in promoting weight gain and in speeding rehabilitation is said to depend on nitrogen retention leading to increased muscle bulk reflected by increased fat-free mass (lean-body mass).	Nitrogen	90-98	FAT atypical cadherin 1	Homo sapiens	165-168
3884249-0	1985	Differences in the inhibitory effects of N-(1-n-dodecyl)-heterocycles on the 2,3-oxidosqualene lanosterol-cyclase of rat liver and yeast.	Nitrogen	41-42	lanosterol synthase	Rattus norvegicus	77-113
16663876-0	1984	Differential role of glutamate dehydrogenase in nitrogen metabolism of maize tissues.	Nitrogen	48-56	glutamic dehydrogenase1	Zea mays	21-44
6383009-7	1984	Total nitrogen losses per subject ranged from 90.5 to 278.7 g. Cumulative nitrogen loss during the first 16 days tended to correlate negatively with initial mean fat cell size and positively with initial lean body mass.	Nitrogen	74-82	FAT atypical cadherin 1	Homo sapiens	162-165
6431132-2	1984	Recent clinical and experimental studies have demonstrated that, under catabolic conditions, treatment with either branched-chain amino acids (BCAA) or insulin may decrease negative nitrogen balance.	Nitrogen	182-190	insulin	Oryctolagus cuniculus	152-159
6431132-7	1984	The results indicate that: (1) nitrogen balance in nontraumatized animals is clearly superior when balanced amino acids are administered; (2) BCAA-enriched solutions may decrease postinjury muscle protein catabolism; (3) after trauma, insulin also has a nitrogen-conserving effect, which is demonstrated when it is combined both with BCAA-enriched (35%) and balanced amino acid (18.8%) solutions.	Nitrogen	254-262	insulin	Oryctolagus cuniculus	235-242
6431132-8	1984	However, a better nitrogen balance is achieved when insulin is associated with the balanced amino acid solution.	Nitrogen	18-26	insulin	Oryctolagus cuniculus	52-59
789791-9	1976	Testing of antibody response to N2 with earlier neuraminidase antigens demonstrated "original antigenic sin" from earlier priming.	Nitrogen	32-34	neuraminidase 1	Homo sapiens	48-61
6682730-4	1983	Further, growth of K-562 in tunicamycin (which inhibits N-linked glycosylations occurring through the lipid intermediate pathway) with or without subsequent treatment with the enzyme neuraminidase, markedly reduced cell surface expression of sugars monitored by lectin binding.	Nitrogen	56-57	neuraminidase 1	Homo sapiens	183-196
6346428-4	1983	Biosynthetic studies showing the incorporation of all four labeled monosaccharides (fucose, mannose, galactose and glucosamine) into the two major subunits of the insulin receptor suggested that both subunits were likely to contain carbohydrate chains of the complex, N-linked type.	Nitrogen	268-269	insulin receptor	Homo sapiens	163-179
1055634-1	1975	An investigation was undertaken of the mechanism of resistance to nitrogen mustard (HN2) and other alkylating agents, with particular emphasis on the interaction between cross-resistance and drug transport mechanisms in L5178Y lymphoblasts.	Nitrogen	66-74	MT-RNR2 like 2 (pseudogene)	Homo sapiens	84-87
6694665-1	1984	The induction of SCE was studied in PHA-stimulated human lymphocytes exposed to nitrogen mustard (HN2) or methyl methanesulfonate (MMS) for various time periods in the G1 phase.	Nitrogen	80-88	MT-RNR2 like 2 (pseudogene)	Homo sapiens	98-101
6304695-5	1983	Such derivatives were obtained taking into account that N-methylation of the ultimate amide bond of dipeptides strongly decreases enkephalinase affinity without affecting angiotension-converting enzyme recognition, whereas retro-inversion of the amide bond leads to the inverse effect.	Nitrogen	56-57	membrane metallo endopeptidase	Mus musculus	130-143
6752121-5	1982	Glutamate:keto-adipate transaminase levels were derepressed two- to fivefold in lys2 mutants using alpha-aminoadipate as a nitrogen source.	Nitrogen	123-131	L-aminoadipate-semialdehyde dehydrogenase	Saccharomyces cerevisiae S288C	80-84
16663033-2	1983	Nitrogen assimilation in three nitrate reductase (NR) mutants of soybean (Glycine max L. Merr.	Nitrogen	0-8	inducible nitrate reductase [NADH] 1	Glycine max	31-48
16663033-2	1983	Nitrogen assimilation in three nitrate reductase (NR) mutants of soybean (Glycine max L. Merr.	Nitrogen	0-8	inducible nitrate reductase [NADH] 1	Glycine max	50-52
238840-3	1975	When mitochondrial ATPase, which has been modified on a single tyrosine residue by 4-chloro-7-nitrobenzofurazan, is incubated at pH 9.0, the 7-nitrobenzofurazan group undergoes an intramolecular transfer to a nitrogen residue.	Nitrogen	209-217	ATP synthase F1 subunit epsilon	Homo sapiens	5-25
6286643-2	1982	Using the human choriocarcinoma cell line, BeWo, we have examined the temporal relationship between N- and O-glycosylation of hCG and the subsequent processing of both types of oligosaccharide chains.	Nitrogen	100-101	chorionic gonadotropin subunit beta 5	Homo sapiens	126-129
24430370-4	1975	These parameters decreased by 80-95% at mid-pod fill, a stage where ovule (seed) development was in the logarithmic growth phase, placing a heavy demand on the plant for both energy and fixed nitrogen.The activity of nitrogen fixation of soybean root nodules bore a reciprocal relationship to that of nitrate reductase.	Nitrogen	217-225	inducible nitrate reductase [NADH] 1	Glycine max	301-318
6286643-4	1982	To more directly study the temporal relationship between N- and O-glycosylation of hCG in BeWo cells, 14C-amino acids and [3H]glucosamine (which also serves as a precursor to N-acetylgalactosamine) were used to label hCG.	Nitrogen	57-58	chorionic gonadotropin subunit beta 5	Homo sapiens	83-86
24430370-5	1975	The maximum levels of nitrogen fixation were reached at early pod fill when nitrate reductase activity had dropped to 25% of maximum activity.	Nitrogen	22-30	inducible nitrate reductase [NADH] 1	Glycine max	76-93
7085637-2	1982	Arylamine N-methyltransferase catalyzes the novel methylation of the ring nitrogen of tryptamine and pyrrole as well as a number of other arylamines including aniline and its derivatives.	Nitrogen	74-82	indolethylamine N-methyltransferase	Homo sapiens	0-29
4416102-0	1974	The binding of microsomal hydroxylation substrates to cytochrome P-450Rh and its effect on the nitrogen fixation by lupin bacteroids.	Nitrogen	95-103	5'-nucleotidase, cytosolic IIIA	Homo sapiens	116-121
6854316-4	1983	Reaction with the form HL-2 (only the amino nitrogen protonated), the dominant form of this species, proceeds by the expected rat limiting water loss (dissociative or Eigen) mechanism with rate constants of 9.3 X 10(7) M-1 sec-1 (+/- 24%) for mono and 5.1 X 10(7) M-1 sec-1 (+/- 25%) for bis complex formation.	Nitrogen	44-52	asialoglycoprotein receptor 2	Rattus norvegicus	23-27
6834148-3	1983	Apparent nitrogen absorption from lupin flour (81.8 and 84.3% of intake) was slightly but significantly less than that during casein control periods (87.2 and 86.8% of intake, P less than 0.05 and less than 0.001).	Nitrogen	9-17	5'-nucleotidase, cytosolic IIIA	Homo sapiens	34-39
6834148-4	1983	Apparent nitrogen retention from unsupplemented lupin (15.6 +/- 5.8% of intake) was significantly less than that from casein in the corresponding control periods (29.8 +/- 4.9%, P less than 0.001); a small but significant (P less than 0.05) increase in nitrogen retention was observed during the control period following the lupin diet when compared with that preceding it.	Nitrogen	9-17	5'-nucleotidase, cytosolic IIIA	Homo sapiens	48-53
6834148-5	1983	Methionine supplementation of lupin produced a marked improvement in apparent nitrogen retention (to 22.2 +/- 6.9%, P less than 0.05).	Nitrogen	78-86	5'-nucleotidase, cytosolic IIIA	Homo sapiens	30-35
16662897-4	1983	The in vivo nitrate reductase activity of N(2)-grown nodules initiated with nitrate reductase-negative mutant strains was less than 10% of the activity shown by nodules initiated with the wild-type strain.	Nitrogen	42-46	chalcone reductase CHR1	Glycine max	20-29
16662897-4	1983	The in vivo nitrate reductase activity of N(2)-grown nodules initiated with nitrate reductase-negative mutant strains was less than 10% of the activity shown by nodules initiated with the wild-type strain.	Nitrogen	42-46	chalcone reductase CHR1	Glycine max	84-93
6831633-2	1983	sensitive Chinese hamster cell line V79/79 has been shown to be also more sensitive to methyl methanesulphonate (MMS) and nitrogen mustard (HN2) exposure than wild-type V79 cells.	Nitrogen	122-130	MT-RNR2 like 2 (pseudogene)	Homo sapiens	140-143
29048124-0	1974	The binding of microsomal hydroxylation substrates to cytochrome P-450Rh and its effect on the nitrogen fixation by lupin bacteroids.	Nitrogen	95-103	5'-nucleotidase, cytosolic IIIA	Homo sapiens	116-121
4723193-0	1973	[Effects of growth hormone and norethandrolone, singly and in combination, on nitrogen balance in the rat.	Nitrogen	78-86	gonadotropin releasing hormone receptor	Rattus norvegicus	12-26
7068676-1	1982	Arthrobacter sialophilus neuraminidase catalyzes the hydrolysis of N-acetylneuraminyl-alpha-oxygen, nitrogen, and azido glycosides.	Nitrogen	100-108	neuraminidase 1	Homo sapiens	25-38
13924614-0	1962	Transamidinase activities, in vitro, of kidneys from rats fed diets supplemented with nitrogen-containing compounds.	Nitrogen	86-94	glycine amidinotransferase	Rattus norvegicus	0-14
6286643-5	1982	The results of these studies are consistent with a model for the N- and O-glycosylation of hCG in which 1) N-glycosylation of hCG occurs co-translationally or very shortly after translation, and 2) the addition of O-linked GalNAc residues to the polypeptide and the addition of peripheral GlcNAc residues to the N-linked oligosaccharide chains occur just prior to secretion, presumably in the Golgi complex.	Nitrogen	65-66	chorionic gonadotropin subunit beta 5	Homo sapiens	126-129
6124544-1	1982	Saccharomyces cerevisiae can use urea as sole nitrogen source by degrading it in two steps (urea carboxylase and allophanate hydrolase) to ammonia and carbon dioxide.	Nitrogen	46-54	hydrolase	Saccharomyces cerevisiae S288C	125-134
7327591-5	1981	We also found that neuraminidase treatment of I-cell fibroblasts before preservative freezing in liquid nitrogen enables the cells to adapt more easily to subculture upon thawing.	Nitrogen	104-112	neuraminidase 1	Homo sapiens	19-32
7050337-7	1982	We found that only in catabolic states did insulin produce a significant nitrogen-sparing effect, probably due to the capacity of the hormone to inhibit muscle proteolysis.	Nitrogen	73-81	insulin	Oryctolagus cuniculus	43-50
6122471-1	1982	Reserpine, a Rauwolfia alkaloid, was shown to increase activity of the hepatic nitrogen metabolizing enzymes xanthine dehydrogenase, purine nucleoside phosphorylase, and tyrosine aminotransferase, when administered orally to young chicks.	Nitrogen	79-87	xanthine dehydrogenase	Gallus gallus	109-131
14495507-2	1961	The reactions of chloroquine mustard (CQM) and nitrogen mustard (HN2) with Ehrlich cells.	Nitrogen	47-55	MT-RNR2 like 2 (pseudogene)	Homo sapiens	65-68
13844375-0	1960	Experiments on the therapeutic index of nitrogen mustard (HN2).	Nitrogen	40-48	MT-RNR2 like 2 (pseudogene)	Homo sapiens	58-61
7013856-0	1981	High-dose nitrogen mustard (HN2) with autologous nonfrozen bone marrow transplantation in advanced malignant melanoma.	Nitrogen	10-18	MT-RNR2 like 2 (pseudogene)	Homo sapiens	28-31
13088927-0	1953	Effect of growth hormone and antibiotics upon nitrogen mustard treated rats.	Nitrogen	46-54	gonadotropin releasing hormone receptor	Rattus norvegicus	10-24
6892166-0	1982	[Effect of increased amounts of soy bean protein in the diet on the development and nitrogen metabolism of 2 generations of rats.	Nitrogen	84-92	brain expressed, associated with NEDD4, 1	Rattus norvegicus	36-40
7013856-2	1981	In a Phase I trial patients with advanced malignant melanoma were treated with high-dose nitrogen mustard (HN2) and autologous bone marrow transplantation.	Nitrogen	89-97	MT-RNR2 like 2 (pseudogene)	Homo sapiens	107-110
6111345-1	1981	The activities of purified (Na+ + K+)-ATPase supported by a series of phosphatidylcholines with monounsaturated (cis-9) fatty acyl chains (di(n : 1) phosphatidylcholine) varying in length from n = 12 to n = 23 were determined by the lipid titration technique.	Nitrogen	87-88	dynein axonemal heavy chain 8	Homo sapiens	38-44
6175048-1	1981	Significantly increased levels of plasma beta-thromboglobulin (beta-TG) (76.8 +/- 25.5 ng/ml, p less than 0.01) were observed in 24 patients with chronic renal failure (blood urea nitrogen (BUN) greater than 20 mg/100 ml), as compared with normal subjects (13.2 +/- 5.6 ng/ml).	Nitrogen	180-188	pro-platelet basic protein	Homo sapiens	41-61
6175048-1	1981	Significantly increased levels of plasma beta-thromboglobulin (beta-TG) (76.8 +/- 25.5 ng/ml, p less than 0.01) were observed in 24 patients with chronic renal failure (blood urea nitrogen (BUN) greater than 20 mg/100 ml), as compared with normal subjects (13.2 +/- 5.6 ng/ml).	Nitrogen	180-188	pro-platelet basic protein	Homo sapiens	63-70
18917249-0	1947	Report on a cooperative study of nitrogen mustard (HN2) therapy of neoplastic disease.	Nitrogen	33-41	MT-RNR2 like 2 (pseudogene)	Homo sapiens	51-54
20250866-0	1946	Comparison of testosterone and growth hormone on the body weight and nitrogen retention of normal and hypophysectomized rats.	Nitrogen	69-77	gonadotropin releasing hormone receptor	Rattus norvegicus	31-45
6111345-2	1981	The ATPase activity at 20 degrees C decreased from 2.9 to 0.1 mumol/min per mg protein as n was decreased from 16 to 12 and decreased from 2.9 to 1.0 mumol/min per mg protein as n was increased from 20 to 23.	Nitrogen	70-71	dynein axonemal heavy chain 8	Homo sapiens	4-10
7019295-2	1981	It was based on N-methylation of normetanephrine by phenylethanolamine-N-methyltransferase using S-adenosyl[methyl-3]methionine as the methyl donor.	Nitrogen	16-17	phenylethanolamine N-methyltransferase	Homo sapiens	52-90
6111345-2	1981	The ATPase activity at 20 degrees C decreased from 2.9 to 0.1 mumol/min per mg protein as n was decreased from 16 to 12 and decreased from 2.9 to 1.0 mumol/min per mg protein as n was increased from 20 to 23.	Nitrogen	85-86	dynein axonemal heavy chain 8	Homo sapiens	4-10
33676207-0	2021	Impacts of Ag and Ag2S nanoparticles on the nitrogen removal within vertical flow constructed wetlands treating secondary effluent.	Nitrogen	44-52	angiotensin II receptor type 1	Homo sapiens	18-22
7013841-6	1981	In Ringer containing Na+, the increase in pHi by insulin occurs when both metabolic and atmospheric sources of CO2 are eliminated by using a 100% N2 atmosphere.	Nitrogen	146-148	glucose-6-phosphate isomerase	Homo sapiens	42-45
33676207-1	2021	In this study, the effects of silver (Ag NPs) and sliver sulfide nanoparticles (Ag2S NPs) on nitrogen removal and nitrogen functional microbes in constructed wetlands were investigated.	Nitrogen	93-101	angiotensin II receptor type 1	Homo sapiens	80-84
6775547-0	1980	Does intravenous fat spare nitrogen in the injured rat?	Nitrogen	27-35	FAT atypical cadherin 1	Rattus norvegicus	17-20
17248969-2	1979	However, alpha-aminoadipate is utilized as a nitrogen source by lys2 and lys5 strains having complete or partial deficiencies of alpha-aminoadipate reductase and, to a limited extent, by heterozygous lys2/+ strains.	Nitrogen	45-53	L-aminoadipate-semialdehyde dehydrogenase	Saccharomyces cerevisiae S288C	64-68
6775547-4	1980	However, when infused without amino acids, fat had the same nitrogen-conserving quality as glucose.	Nitrogen	60-68	FAT atypical cadherin 1	Rattus norvegicus	43-46
7468251-5	1980	Inhibition of cardiac contractility in response to increasing concentrations of N2+ (10(-7)--10(-3) M), in the presence of 1.3 mM  Cap2+, proved to be dose-dependent, whereas the amplitude of TCR elevation reached its maximum already at Ni2+ concentration of 10(-6) M. The present results emphasize the biomedical significance of this trace metal.	Nitrogen	80-83	cyclase associated actin cytoskeleton regulatory protein 2	Rattus norvegicus	131-135
11219850-0	1980	Sensitivity of the conformation of deoxyguanosine to binding at the C-8 position by N-acetylated and unacetylated 2-aminofluorene.	Nitrogen	84-85	homeobox C8	Homo sapiens	68-71
33647655-4	2021	The annual DOC and TDN fluxes were estimated to be 6.42 kg ha-1 yr-1 and 3.39 kg ha-1 yr-1, respectively, indicating that precipitation was a significant factor in C and N deposition.	Nitrogen	21-22	keratin 31	Homo sapiens	59-74
33647655-4	2021	The annual DOC and TDN fluxes were estimated to be 6.42 kg ha-1 yr-1 and 3.39 kg ha-1 yr-1, respectively, indicating that precipitation was a significant factor in C and N deposition.	Nitrogen	21-22	keratin 31	Homo sapiens	59-68
34032712-9	2021	Patients with severe HTGP had significantly more pancreatic necrosis, higher values of Blood urea nitrogen and creatinine, longer prothrombin time and activated partial thromboplastin time on admission and higher CRP48 than not severe HTGP (P < .05).The severity of HTGP was significantly related to clinical factors including fever, altered mental status, rapid pulse, hypotension, and pancreatic necrosis.	Nitrogen	98-106	transglutaminase 4	Homo sapiens	21-25
33831352-0	2021	Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis.	Nitrogen	8-16	RHO-related protein from plants 2	Arabidopsis thaliana	45-49
33831352-5	2021	Interestingly, nitrate, ammonium, and glutamine all activate the small GTPase Rho-related protein from plants 2 (ROP2), and constitutively active ROP2 restores TOR activation under nitrogen-starvation conditions.	Nitrogen	181-189	RHO-related protein from plants 2	Arabidopsis thaliana	113-117
33831352-5	2021	Interestingly, nitrate, ammonium, and glutamine all activate the small GTPase Rho-related protein from plants 2 (ROP2), and constitutively active ROP2 restores TOR activation under nitrogen-starvation conditions.	Nitrogen	181-189	RHO-related protein from plants 2	Arabidopsis thaliana	146-150
33831352-6	2021	Our findings suggest that specific evolutionary adaptations of the nitrogen-TOR signaling pathway occurred in plant lineages, and ROP2 can integrate diverse nitrogen and hormone signals for plant TOR activation.	Nitrogen	67-75	RHO-related protein from plants 2	Arabidopsis thaliana	130-134
33831352-6	2021	Our findings suggest that specific evolutionary adaptations of the nitrogen-TOR signaling pathway occurred in plant lineages, and ROP2 can integrate diverse nitrogen and hormone signals for plant TOR activation.	Nitrogen	157-165	RHO-related protein from plants 2	Arabidopsis thaliana	130-134
307433-0	1978	Response of CBA/N mice to human B cell activating factor.	Nitrogen	16-17	TNF superfamily member 13b	Homo sapiens	32-56
17248969-2	1979	However, alpha-aminoadipate is utilized as a nitrogen source by lys2 and lys5 strains having complete or partial deficiencies of alpha-aminoadipate reductase and, to a limited extent, by heterozygous lys2/+ strains.	Nitrogen	45-53	holo-[acyl-carrier-protein] synthase	Saccharomyces cerevisiae S288C	73-77
33609882-1	2021	This study focused on the nitrous oxide (N2O) generation from the biological nitrogen removal process under different pH levels.	Nitrogen	77-85	phenylalanine hydroxylase	Homo sapiens	118-120
33609882-6	2021	The impacts of pH on N2O generation were more likely related to the response of bacterial enzymes and nitrogen compounds, rather than the feedback of bacterial community structure itself.	Nitrogen	102-110	phenylalanine hydroxylase	Homo sapiens	15-17
672681-2	1978	Nucleic acids added to the medium as a source of nitrogen or phosphorus stimulated synthesis of ribonuclease.	Nitrogen	49-57	AKO65_RS07180	Bacillus pumilus	96-108
17248969-3	1979	Lys2 mutants were conveniently selected on media containing alpha-aminoadipate as a nitrogen source, lysine, and other supplements to furnish other possible auxotrophic requirements.	Nitrogen	84-92	L-aminoadipate-semialdehyde dehydrogenase	Saccharomyces cerevisiae S288C	0-4
33609882-7	2021	Above all, an influent pH range of 6-8 is recommended for nitrogen removal and N2O mitigation in anoxic-oxic process.	Nitrogen	58-66	phenylalanine hydroxylase	Homo sapiens	23-25
363509-0	1978	[Effect of B polA1- exrA- and recA-gene mutations on the reparation of single-strand DNA breaks induced by N-nitrosomethylurea].	Nitrogen	86-87	DNA polymerase alpha 1, catalytic subunit	Homo sapiens	13-18
342293-0	1978	Remissions of mycosis fungoides induced by nitrogen mustard (HN2).	Nitrogen	43-51	MT-RNR2 like 2 (pseudogene)	Homo sapiens	61-64
566707-7	1978	These differences in growth hormone secretion may be responsible for the impaired nitrogen retention in the obese rat.	Nitrogen	82-90	gonadotropin releasing hormone receptor	Rattus norvegicus	21-35
344245-5	1978	A derivative of the synthetic LH-RH formylated at the indole nitrogen had a greatly diminished biological activity, indicating that the intact indole side chain is essential for the activity.	Nitrogen	61-69	gonadotropin releasing hormone 1	Homo sapiens	30-35
33788965-0	2021	Posttranslational regulation of CALHM1/3 channel: N-linked glycosylation and S-palmitoylation.	Nitrogen	50-51	calcium homeostasis modulator 1	Homo sapiens	32-40
33788965-4	2021	Biochemical analyses of the two subunits following site-directed mutagenesis and pharmacological treatments established that both CALHM1 and 3 were N-glycosylated at single Asn residues in their second extracellular loops.	Nitrogen	148-149	calcium homeostasis modulator 1	Homo sapiens	130-142
33788965-12	2021	Overall, this study characterized N-glycosylation and S-palmitoylation of CALHM1/3 subunits and clarified their differential contributions to its functional expression, providing insights into the fine control of the CALHM1/3 channel and associated physiological processes.	Nitrogen	34-35	calcium homeostasis modulator 1	Homo sapiens	74-82
33788965-12	2021	Overall, this study characterized N-glycosylation and S-palmitoylation of CALHM1/3 subunits and clarified their differential contributions to its functional expression, providing insights into the fine control of the CALHM1/3 channel and associated physiological processes.	Nitrogen	34-35	calcium homeostasis modulator 1	Homo sapiens	217-225
24432-3	1978	Specific activity of IF in the alkaline eluate was increased by a factor in excess of 200 and the IF thus recovered had probably retained most of the N-ANA moieties.	Nitrogen	150-151	interferon beta 1	Homo sapiens	21-23
963075-10	1976	Leghaemoglobin had an apparent half-life of 18 days and is a stable protein in nitrogen-fixing yellow lupin nodules.	Nitrogen	79-87	5'-nucleotidase, cytosolic IIIA	Homo sapiens	102-107
959674-4	1976	In 5 subjects a transient increase in Pdi of 25-150 cm H2O consistently produced a transient increase in expired N2 concentration of 1.80 +/- 0.06% (Mean +/- 1 SE); in 1 subject N2 concentration decreased by 0.8% to 2.7% N2, and in one subject the alveolar plateau was uninfluenced by changes in Pdi.	Nitrogen	113-115	prolyl 4-hydroxylase subunit beta	Homo sapiens	38-41
959674-4	1976	In 5 subjects a transient increase in Pdi of 25-150 cm H2O consistently produced a transient increase in expired N2 concentration of 1.80 +/- 0.06% (Mean +/- 1 SE); in 1 subject N2 concentration decreased by 0.8% to 2.7% N2, and in one subject the alveolar plateau was uninfluenced by changes in Pdi.	Nitrogen	178-180	prolyl 4-hydroxylase subunit beta	Homo sapiens	38-41
959674-4	1976	In 5 subjects a transient increase in Pdi of 25-150 cm H2O consistently produced a transient increase in expired N2 concentration of 1.80 +/- 0.06% (Mean +/- 1 SE); in 1 subject N2 concentration decreased by 0.8% to 2.7% N2, and in one subject the alveolar plateau was uninfluenced by changes in Pdi.	Nitrogen	178-180	prolyl 4-hydroxylase subunit beta	Homo sapiens	38-41
16659611-9	1976	In vivo studies indicated a lower inactivation temperature for NADPH-glutamate dehydrogenase; however, it was still more heat-tolerant than nitrate reductase.We envisaged that reduced nitrogen supplied by NO(3) (-) assimilation is a factor in leaf expansion.	Nitrogen	184-192	inducible nitrate reductase [NADH] 1	Glycine max	140-157
975018-1	1976	In vivo treatment of sensitive tumor cells with nitrogen mustard (HN2) results in marked inhibitions of protein and nucleic acid synthesis by mitochondria subsequently isolated from these cells.	Nitrogen	48-56	MT-RNR2 like 2 (pseudogene)	Homo sapiens	66-69
24432-3	1978	Specific activity of IF in the alkaline eluate was increased by a factor in excess of 200 and the IF thus recovered had probably retained most of the N-ANA moieties.	Nitrogen	150-151	interferon beta 1	Homo sapiens	98-100
18351-3	1977	The results suggest that Mg2+ binds simultaneously to one (or both) of the two free oxygen atoms of the beta-phosphate moiety and to the nitrogen atom of the phosphate chain (P alpha-O-P beta-N-P gamma).	Nitrogen	137-145	mucin 7, secreted	Homo sapiens	25-28
64436-1	1976	A report is presented on the performance of the correction of PTT by means of factor VIII and IX deficiency plasma, which may be used at least one year, when preserved in liquid nitrogen.	Nitrogen	178-186	cytochrome c oxidase subunit 8A	Homo sapiens	85-89
13991-1	1977	Previous studies have shown that a group of nitrogen catabolic enzymes including xanthine dehydrogenase, purine nucleoside phosphorylase, and tyrosine aminotransferase are all increased in chick liver by dietary protein as well as single amino acids (e.g. methionine) and certain antimetabolites (e.g. hydrazine).	Nitrogen	44-52	xanthine dehydrogenase	Gallus gallus	81-103
1228249-5	1975	The pretreatment with N-IgG prolonged significantly cyclobarbital-induced sleeping time as compared with that of saline treated group, however, in the Ab-IgG treated group the duration of the sleeping was much the same as that seen in the saline group.	Nitrogen	22-23	immunoglobulin heavy chain (V7183 family)	Mus musculus	24-27
1228249-5	1975	The pretreatment with N-IgG prolonged significantly cyclobarbital-induced sleeping time as compared with that of saline treated group, however, in the Ab-IgG treated group the duration of the sleeping was much the same as that seen in the saline group.	Nitrogen	22-23	immunoglobulin heavy chain (V7183 family)	Mus musculus	151-157
197760-3	1977	And on the contrary in cases of Erb"s and Landouzy-Dejerine myopathy the changes of nitrogen metabolism are due to an increased content of cyclic AMP.	Nitrogen	84-92	estrogen receptor 2	Homo sapiens	32-35
1212501-0	1975	[The effects of arginine and growth hormone on the nitrogen balance of rats].	Nitrogen	51-59	gonadotropin releasing hormone receptor	Rattus norvegicus	29-43
1269114-5	1976	Microsomal renin was also isolated from rat kidney disrupted by the N2 cavitation technique.	Nitrogen	68-70	renin	Rattus norvegicus	11-16
4577503-0	1973	Complete remissions of mycosis fungoides lymphoma induced by topical nitrogen mustard (HN2).	Nitrogen	69-77	MT-RNR2 like 2 (pseudogene)	Homo sapiens	87-90
132455-4	1976	In 7 GH-deficient children and 3 adults with myotonic dystrophy, we measured the capacity of human GH (hGH), pGH, and pGH plasmin digests to cause: a) the retention of N, P, K, Na, and Cl; b) a rise in plasma free fatty acids; c) a fall in plasma alpha-amino NL d) impaired glucose tolerance; and e) hyperinsulinemia.	Nitrogen	168-169	plasminogen	Homo sapiens	122-129
4727786-0	1973	Protective effect of thiosulfate and metabolic thiosulfate precursors against toxicity of nitrogen mustard (HN2).	Nitrogen	90-98	MT-RNR2 like 2 (pseudogene)	Homo sapiens	108-111
176269-7	1976	By contrast, some NIH Swiss mice exposed to N-tropic virus at birth made anti-VEA antibodies and eliminated the virus.	Nitrogen	18-19	CD69 antigen	Mus musculus	78-81
16657914-13	1972	Thus, based on previous estimates of approximately 32% of the final N distribution being in the vegetative plant parts, the estimated input of reduced nitrogen via the enzyme assay was in agreement with the actual N accumulation.The amount of calculated N(2)-fixation by nodules per season with plants grown in hydroponics was less than 2% of the computed nitrate reduced via leaf nitrate reductase.	Nitrogen	151-159	inducible nitrate reductase [NADH] 1	Glycine max	381-398
1141230-5	1975	Moreover, the NMR spectra have also shown that the nitrogen mustard reacts with the beta2 histidines of the hemoglobin molecule and have suggested that several other surface amino acid residues of the hemoglobin molecule are also affected by the nitrogen mustard alkylation.	Nitrogen	51-59	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	84-89
5775714-0	1969	A study on the mechanism of resistance to nitrogen mustard (HN2) in Ehrlich ascites tumor cells: comparison of uptake of HN2-14-C into sensitive and resistant cells.	Nitrogen	42-50	MT-RNR2 like 2 (pseudogene)	Homo sapiens	60-63
4239123-0	1969	ATPase content of striated muscle stressed in O2-CO2 and hyperbaric N2-O2-CO2 atmospheres.	Nitrogen	68-70	dynein axonemal heavy chain 8	Homo sapiens	0-6
1141230-5	1975	Moreover, the NMR spectra have also shown that the nitrogen mustard reacts with the beta2 histidines of the hemoglobin molecule and have suggested that several other surface amino acid residues of the hemoglobin molecule are also affected by the nitrogen mustard alkylation.	Nitrogen	246-254	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	84-89
4843941-0	1974	[Effect of substrates and microsomal hydroxylation inhibitors on the nitrogen-fixing activity of lupin bacteroids].	Nitrogen	69-77	5'-nucleotidase, cytosolic IIIA	Homo sapiens	97-102
16349813-7	1968	Approximately 90% removal of the carbon source (expressed as chemical oxygen demand, COD) was attained with a low level of supplemental nitrogen (COD/N = 70:1) and a fairly low reactor detention time (4 hr).	Nitrogen	136-144	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	85-88
4912770-0	1970	Early detection of injury after nitrogen mustard (HN2) therapy: the radioiron disappearance rate as a dosimeter.	Nitrogen	32-40	MT-RNR2 like 2 (pseudogene)	Homo sapiens	50-53
4380491-0	1966	The relationship between caries activity, flow rate, total nitrogen and the mucin content of saliva.	Nitrogen	59-67	LOC100508689	Homo sapiens	76-81
5311893-0	1970	Recovery of supralethally x-irradiated and nitrogen mustard (HN2)-treated amoebae.	Nitrogen	43-51	MT-RNR2 like 2 (pseudogene)	Homo sapiens	61-64
5966455-0	1966	Nitrogen and sulphur requirements of Colletotrichum inamdarii Lal.	Nitrogen	0-8	lipase A, lysosomal acid type	Homo sapiens	62-65
14348191-3	1965	The xanthine-dehydrogenase activity of chick liver, expressed per mg. of nitrogen, is increased during starvation.	Nitrogen	73-81	xanthine dehydrogenase	Gallus gallus	4-26
5852362-0	1965	Urea and biuret as nitrogen sources for Rhizobium spp.	Nitrogen	19-27	histocompatibility minor 13	Homo sapiens	50-53
14247714-2	1964	Data are given on the amounts of antibody nitrogen precipitated in the crossreactions, often reciprocal, of the specific capsular polysaccharides of the pneumococcal type pairs II and XX, II and XIX, VII and XIV, VII and XVIII, VII and XIX, VIII and XVIII, VIII and XIX, X and XIV, and X and XX.	Nitrogen	42-50	cytochrome c oxidase subunit 8A	Homo sapiens	222-226
14247714-2	1964	Data are given on the amounts of antibody nitrogen precipitated in the crossreactions, often reciprocal, of the specific capsular polysaccharides of the pneumococcal type pairs II and XX, II and XIX, VII and XIV, VII and XVIII, VII and XIX, VIII and XVIII, VIII and XIX, X and XIV, and X and XX.	Nitrogen	42-50	cytochrome c oxidase subunit 8A	Homo sapiens	241-245
19867206-5	1961	In an effort to account physiologically for the manner in which endotoxin suppresses or prevents the rise in urinary nitrogen excreted in response to ACTH, blood non-protein nitrogen levels (NPN) were determined.	Nitrogen	117-125	pro-opiomelanocortin-alpha	Mus musculus	150-154
13848079-10	1959	The number of heat-killed cells of S. typhimurium required to block the increase in urinary nitrogen caused by an injection of ACTH was found to be 10(8).	Nitrogen	92-100	pro-opiomelanocortin-alpha	Mus musculus	127-131
13848079-12	1959	Mice infected with S. typhimurium excreted less than the normal amount of urinary nitrogen in response to ACTH 6 to 23 hours postinfection while normal amounts of nitrogen were eliminated 54 to 71 hours postinfection.	Nitrogen	82-90	pro-opiomelanocortin-alpha	Mus musculus	106-110
13499433-0	1957	On the relation between nitrogen fixation and nodule nitrate reductase of soybean root nodules.	Nitrogen	24-32	inducible nitrate reductase [NADH] 1	Glycine max	53-70
13231828-0	1955	Reduction of the nitrogen-retaining effect of growth hormone in normal and adrenalectomized pantothenic acid-deficient rats.	Nitrogen	17-25	gonadotropin releasing hormone receptor	Rattus norvegicus	46-60
14781170-1	1950	I. Inhibitory action of nitrogen mustard (HN2).	Nitrogen	24-32	MT-RNR2 like 2 (pseudogene)	Homo sapiens	42-45
33690084-4	2021	We find that total organic carbon (TOC) and total nitrogen (TN) accumulation rates have increased in the estuary since the 1980"s, directly related to rapid urban development.	Nitrogen	50-58	C-type lectin domain family 3 member B	Homo sapiens	60-62
13240307-1	1955	V. Effect of nitrogen mustard (HN2).	Nitrogen	13-21	MT-RNR2 like 2 (pseudogene)	Homo sapiens	31-34
33965819-2	2021	The objective of this study was to analyse the variation in outflows of soil total nitrogen (TN) and available phosphorus (Pav) as influenced by land use types (cropland, grazing land, and bushland) and land management practices (soil bunds for cropland and exclosures for non-croplands) in the three contrasting agro-ecological zones of the Upper Blue Nile basin, Ethiopia.	Nitrogen	83-91	C-type lectin domain family 3 member B	Homo sapiens	93-95
33884581-0	2021	The Antipsychotic Drug Clozapine Suppresses the RGS4 Polyubiquitylation and Proteasomal Degradation Mediated by the Arg/N-Degron Pathway.	Nitrogen	120-121	regulator of G protein signaling 4	Homo sapiens	48-52
33836649-11	2021	CONCLUSIONS: N/OFQ exacerbated orofacial pain possibly through upregulating CGRP.	Nitrogen	2-3	calcitonin-related polypeptide alpha	Rattus norvegicus	76-80
33727825-1	2021	Background: Ribophorin II (RPN2) is a highly conserved glycoprotein involved in the N-linked glycosylation of multiple proteins.	Nitrogen	29-30	ribophorin II	Homo sapiens	12-25
33436225-4	2021	CRG exhibited improved degree of order and reduced graphitization defect, N-5 and OI groups were the dominant nitrogen and oxygen-containing groups.	Nitrogen	110-118	chromodomain helicase DNA binding protein 7	Homo sapiens	0-3
33187836-4	2021	Results indicated that total N (TN) runoff loss rates from uplands and paddy fields consistently increased from upstream to downstream regions.	Nitrogen	29-30	C-type lectin domain family 3 member B	Homo sapiens	32-34
33434865-10	2021	Yield-scaled N2O emissions (0.05 +- 0.01 kg N2O-N Mg-1 yr-1) and nitrogen leaching (0.79 +- 0.08 kg N Mg-1 yr-1) were lowest at fertilizer rates <1000 kg N ha-1 yr-1.	Nitrogen	13-14	solute carrier family 9 member B1	Homo sapiens	154-165
33434865-12	2021	Our study indicates that high environmental N2O and N leaching losses can be mitigated by reducing fertilization rates to 500-1000 kg N ha-1 yr-1 (mean: ~762 kg N ha-1 yr-1) without jeopardizing yields.	Nitrogen	44-45	solute carrier family 9 member B1	Homo sapiens	134-145
33434865-12	2021	Our study indicates that high environmental N2O and N leaching losses can be mitigated by reducing fertilization rates to 500-1000 kg N ha-1 yr-1 (mean: ~762 kg N ha-1 yr-1) without jeopardizing yields.	Nitrogen	44-45	solute carrier family 9 member B1	Homo sapiens	161-172
33398631-2	2021	We previously showed that nitrogen-containing bisphosphonate (NBP)-treatment induces extramedullary hematopoiesis via G-CSF stimulation.	Nitrogen	26-34	colony stimulating factor 3 (granulocyte)	Mus musculus	118-123
33555173-4	2021	The combination of the CrBr3 monolayer with N-terminated GaN nanosheets leads to enhanced FM coupling via superexchange interactions between the Cr-t2g and Cr-eg orbitals, consequently resulting in a Curie temperature of CrBr3 of up to 67 K. Moreover, self-doped p-n junctions can be naturally formed in the heterostructures without additional modulation of external fields.	Nitrogen	9-10	gigaxonin	Homo sapiens	57-60
33629527-3	2021	The influenza A virus (IAV) proteins hemagglutinin (HA) and neuraminidase (NA) have multiple N-glycosylation sites, and alteration of N-glycan micro- and macroheterogeneity can have strong effects on virulence and immunogenicity.	Nitrogen	75-76	neuraminidase 1	Homo sapiens	60-73
33624829-4	2021	The mtETC produces reactive oxygen and nitrogen species, which can act as signals or lead to cellular damage, and are thus efficiently removed by mitochondrial antioxidant systems, including Mn-superoxide dismutase, ascorbate-glutathione cycle and thioredoxin-dependent peroxidases.	Nitrogen	39-47	superoxide dismutase 2	Homo sapiens	191-214
33544264-9	2021	The higher TOC/TN ratio (4.24-14.5) indicated low nitrogen content organic matter in the fjord sediments through glacier runoff, which enhances the abundance and diversity of nitrogen fixing microorganisms.	Nitrogen	50-58	C-type lectin domain family 3 member B	Homo sapiens	15-17
33406838-0	2021	N- and O-Glycosylation of the SARS-CoV-2 Spike Protein.	Nitrogen	0-1	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	41-46
33552834-5	2021	Another striking observation is the absence of N-glycosylation site Asn103 in all mammals and many species, lack more than one N-linked glycosylation site in the ACE2 receptor.	Nitrogen	127-128	angiotensin converting enzyme 2	Homo sapiens	162-166
32986911-4	2021	Based on data from previous 15 N-tracer trials, the authors demonstrated that N uptake from nonfertilizer inputs and previous years" fertilizer only contributed a "small" or "modest" part to the Ndfo, leaving a significant N source (approximately 53 kg N ha-1 yr-1 ) not yet accounted for and speculated to be from soil N turnover.	Nitrogen	78-79	solute carrier family 9 member B1	Homo sapiens	253-264
32986911-4	2021	Based on data from previous 15 N-tracer trials, the authors demonstrated that N uptake from nonfertilizer inputs and previous years" fertilizer only contributed a "small" or "modest" part to the Ndfo, leaving a significant N source (approximately 53 kg N ha-1 yr-1 ) not yet accounted for and speculated to be from soil N turnover.	Nitrogen	78-79	solute carrier family 9 member B1	Homo sapiens	253-264
32986911-4	2021	Based on data from previous 15 N-tracer trials, the authors demonstrated that N uptake from nonfertilizer inputs and previous years" fertilizer only contributed a "small" or "modest" part to the Ndfo, leaving a significant N source (approximately 53 kg N ha-1 yr-1 ) not yet accounted for and speculated to be from soil N turnover.	Nitrogen	78-79	solute carrier family 9 member B1	Homo sapiens	253-264
33345971-5	2021	By employing iso-propanol as solvent and H-donor, and palladium nanoparticles immobilized on nitrogen-doped carbon (Pd/CNX) as efficient multifunctional catalyst, veratryl alcohol dehydroxylation exhibited almost 100% conversion along with very high selectivity for 1,2-dimethoxy-benzene (46%) and 3,4-dimethoxytoluene (54%).	Nitrogen	93-101	calnexin	Homo sapiens	119-122
33189421-8	2021	The average total N input to croplands increased from 24 and 19 kg N ha-1 yr-1 in 1961-1965 to 100 and 42 kg N ha-1 yr-1 in 2010-2017 for North Africa and SSA, respectively.	Nitrogen	18-19	solute carrier family 9 member B1	Homo sapiens	67-78
33189421-8	2021	The average total N input to croplands increased from 24 and 19 kg N ha-1 yr-1 in 1961-1965 to 100 and 42 kg N ha-1 yr-1 in 2010-2017 for North Africa and SSA, respectively.	Nitrogen	18-19	solute carrier family 9 member B1	Homo sapiens	109-120
32787654-6	2021	Results from the N rate trial at both locations indicated that only the highest (29.3 kg N ha-1) rate consistently reduced dollar spot severity relative to the non-treated control.	Nitrogen	17-18	solute carrier family 9 member B1	Homo sapiens	89-95
31601159-3	2021	While LARP1 represses TOP mRNA translation via the C-terminal DM15 region, the role of the N-terminal La-Module in the recognition and translational regulation of TOP mRNAs remains elusive.	Nitrogen	28-29	La ribonucleoprotein 1, translational regulator	Homo sapiens	6-11
33393538-1	2021	The regioselective gamma-C-H amination of the side-chain of saturated 2-alkyl nitrogen heterocycles is reported, proceeding through a sulfamide-directed 1,6-radical translocation.	Nitrogen	78-86	interleukin 2 receptor subunit gamma	Homo sapiens	19-26
33316563-9	2021	Finally, the MOF packed in pipette tip was applied to selectively capture the N-linked endogenous glycopeptides from a healthy saliva sample and 64 unique endogenous glycopeptides were identified.	Nitrogen	78-79	lysine acetyltransferase 8	Homo sapiens	13-16
33254961-6	2021	Besides, the N,O-CMC2/OCS1 hydrogel revealed excellent antibacterial properties due to the inherent antibacterial ability of N,O-CMC.	Nitrogen	13-15	COX assembly mitochondrial protein 2	Mus musculus	17-21
18863686-0	1948	Production of nitrogen retention in hypophysectomized rats by small doses of hypophyseal growth hormone.	Nitrogen	14-22	gonadotropin releasing hormone receptor	Rattus norvegicus	89-103
16560177-0	1938	Nitrogen Availability as an Aid in the Differentiation of Bacteria in the Coli-Aerogenes Group.	Nitrogen	0-8	activation induced cytidine deaminase	Homo sapiens	28-31
33507513-1	2021	Replenishing soil nutrient particularly total nitrogen (TN) and available phosphorus (P) is important to sustain soil health for food production.	Nitrogen	46-54	C-type lectin domain family 3 member B	Homo sapiens	56-58
33736179-3	2021	TAF-DOC incorporates various environmental factors (e.g., meteorology, sulfur, and nitrogen deposition) that to-date have not been comprehensively considered or well-represented in existing modeling frameworks.	Nitrogen	83-91	TATA-box binding protein associated factor 8	Homo sapiens	0-3
34039637-2	2021	Dampening miR-21 activity was previously shown to reduce splenomegaly and blood urea nitrogen levels in SLE-prone mice, but the detailed cellular responses and mechanism of action remains unexplored.	Nitrogen	85-93	microRNA 21a	Mus musculus	10-16
34029479-4	2021	Mechanistic studies by DFT calculations reveal that the triple insertion of PhCN into 2a proceeds through four key steps: the insertion of the first PhCN into 2a giving azalutetacyclopentadiene IM1, the insertion of the second PhCN into the Lu-N bond of IM1, the intramolecular electrocyclization providing a highly strained eta2-pyrimidine metallacycle, and the insertion of the third PhCN into the Lu-Csp3 bond.	Nitrogen	79-80	DNA polymerase iota	Homo sapiens	325-329
34009575-6	2021	The existence of crab caves greatly promoted the nitrogen exchange flux at the sediment-water interface, and the mean exchange fluxes of NH4+-N, NO3--N and TN were 51.40 mmol (m2 day)-1, -13.44 mmol (m2 day)-1 and 39.74 mmol (m2 day)-1, respectively (much higher than those measured in the control box), implying that NH4+-N and TN were released from the sediment to the overlying water, while NO3--N was released from the overlying water to the sediment.	Nitrogen	49-57	C-type lectin domain family 3 member B	Homo sapiens	156-158
34009575-6	2021	The existence of crab caves greatly promoted the nitrogen exchange flux at the sediment-water interface, and the mean exchange fluxes of NH4+-N, NO3--N and TN were 51.40 mmol (m2 day)-1, -13.44 mmol (m2 day)-1 and 39.74 mmol (m2 day)-1, respectively (much higher than those measured in the control box), implying that NH4+-N and TN were released from the sediment to the overlying water, while NO3--N was released from the overlying water to the sediment.	Nitrogen	49-57	C-type lectin domain family 3 member B	Homo sapiens	329-331
32926618-2	2021	A comparison of the reaction times required for the reduction of nitrogen-containing oxyanions (NOx-, x = 2, 3) by the POV-ethoxide cluster in its anionic (1-V6O61-; VIIIVIV5), neutral (4-V6O60; VIIIVIV4VV), or cationic (6-V6O61+; VIIIVIV3VV2) charge state reveals that OAT is significantly influenced by three factors: (1) ion-pairing interactions between the POV-alkoxide and the negatively charged oxyanion; (2) oxidation states of remote vanadyl ions in the Lindqvist assembly; (3) the steric bulk surrounding the coordinatively unsaturated VIII ion.	Nitrogen	65-73	cytochrome c oxidase subunit 8A	Homo sapiens	166-170
33962942-4	2021	Here, we show that exostosin-1 (EXT1) glycosyltransferase, an enzyme involved in N-glycosylation, is a key regulator of ER morphology and dynamics.	Nitrogen	81-82	exostosin glycosyltransferase 1	Homo sapiens	19-30
33962942-4	2021	Here, we show that exostosin-1 (EXT1) glycosyltransferase, an enzyme involved in N-glycosylation, is a key regulator of ER morphology and dynamics.	Nitrogen	81-82	exostosin glycosyltransferase 1	Homo sapiens	32-36
33962942-4	2021	Here, we show that exostosin-1 (EXT1) glycosyltransferase, an enzyme involved in N-glycosylation, is a key regulator of ER morphology and dynamics.	Nitrogen	81-82	epiregulin	Homo sapiens	120-122
33991925-4	2021	It was found that from 1998 to 2018 the N input increased from 274.63 to 848.65 kg N ha-1.	Nitrogen	40-41	solute carrier family 9 member B1	Homo sapiens	83-89
33947300-11	2021	A new predictor, ubeta2-MG and blood urea nitrogen (BUN); named BB1, was substituted as the diagnostic value in neonates with asphyxia with an area under the receiver operating characteristic curve (AUC) (95% CI) of 0.88 (0.76-1.0).	Nitrogen	42-50	neuromedin B receptor	Homo sapiens	64-67
33429272-5	2021	NH4NO3 addition of 50 kg N ha-1 yr-1 significantly increased organic N derived N2O on the 6th day after N addition, which suggests that heterotrophic nitrification may be the dominating process with higher N deposition rate.	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	25-36
33429272-5	2021	NH4NO3 addition of 50 kg N ha-1 yr-1 significantly increased organic N derived N2O on the 6th day after N addition, which suggests that heterotrophic nitrification may be the dominating process with higher N deposition rate.	Nitrogen	3-4	solute carrier family 9 member B1	Homo sapiens	25-36
33429272-5	2021	NH4NO3 addition of 50 kg N ha-1 yr-1 significantly increased organic N derived N2O on the 6th day after N addition, which suggests that heterotrophic nitrification may be the dominating process with higher N deposition rate.	Nitrogen	3-4	solute carrier family 9 member B1	Homo sapiens	25-36
33935494-11	2021	Conclusion: Alendronate application partially reversed the suppression of expression of BMP2, EIF2AK3, EIF2A, ATF4 caused by liquid nitrogen.	Nitrogen	132-140	bone morphogenetic protein 2	Rattus norvegicus	88-92
33935494-11	2021	Conclusion: Alendronate application partially reversed the suppression of expression of BMP2, EIF2AK3, EIF2A, ATF4 caused by liquid nitrogen.	Nitrogen	132-140	eukaryotic translation initiation factor 2 alpha kinase 3	Rattus norvegicus	94-101
33893369-5	2021	Analysis using mixed effects models for repeated measures with adjustment for age and sex showed that serum SDC-1 levels measured the day before significantly affected several outcomes, including aspartate aminotransferase (AST), alanine transaminase (ALT), creatinine (CRE), blood urea nitrogen (BUN), antithrombin III, fibrin degradation products, and D-dimer.	Nitrogen	287-295	syndecan 1	Homo sapiens	108-113
33886138-5	2021	CoS 2 /S@N-HCS composite exhibits a specific capacity of 729.6 mAh g -1 after 500 cycles at a current density of 1 A g -1 .	Nitrogen	9-10	holocarboxylase synthetase	Homo sapiens	11-14
33886138-7	2021	The excellent cycling performance and rate capability demonstrated that the CoS 2 /S@N-HCS is a potential and prospective anode material for sodium-ion batteries.	Nitrogen	85-86	holocarboxylase synthetase	Homo sapiens	87-90
33856229-2	2021	It contains a labile Fe2S2(His)1(Cys)3 metal cluster with a single Fe-N(His87) coordinating bond and can transfer its cluster to acceptor proteins.	Nitrogen	70-71	viral integration site 1	Homo sapiens	21-32
33067044-5	2021	Quantitative N-glycoproteomic analysis showed that the abundance of 32 N-glycosites from 18 N-glycoproteins (such as Mucin 5B) of SD-EW was significantly reduced comparing to F-EW, indicated that the N-glycans of egg white protein are likely to be covalently cross-linked during spray-drying and are involved in thermal aggregation.	Nitrogen	13-14	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	117-125
33067044-5	2021	Quantitative N-glycoproteomic analysis showed that the abundance of 32 N-glycosites from 18 N-glycoproteins (such as Mucin 5B) of SD-EW was significantly reduced comparing to F-EW, indicated that the N-glycans of egg white protein are likely to be covalently cross-linked during spray-drying and are involved in thermal aggregation.	Nitrogen	71-72	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	117-125
33859186-7	2021	These findings indicated that S-nitrosylation at Cys351 of PFKM by NOS1 contributes to the metabolic reprogramming of ovarian cancer cells, highlighting a critical role of endogenous nitrogen oxide on metabolism regulations in tumor progression.	Nitrogen	183-191	nitric oxide synthase 1, neuronal	Mus musculus	67-71
33290375-10	2021	RESULTS: The plasma ccf mt-DNA levels of both ND1 and CYTC were significantly decreased in patients with CS compared with levels in controls both in total and by sex, while the plasma ccf n-DNA levels showed no significant difference.	Nitrogen	51-52	citrate synthase	Homo sapiens	105-107
33838471-2	2021	As such, we investigated whether the blood urea nitrogen (BUN)/albumin ratio (BAR) predicts mortality in the COVID-19 patients in the emergency department.	Nitrogen	48-56	bifunctional apoptosis regulator	Homo sapiens	78-81
33916471-8	2021	The levels of HMGB1 and 4-hydroxynonenal (4-HNE), as respective markers of reactive nitrogen species (RNS) and ROS formation, showed slight increases on post-exposure day 1 and achieved their highest levels on post-exposure day 4.	Nitrogen	84-92	high mobility group box 1	Mus musculus	14-19
33733754-6	2021	Its microscopic origin is the unusual linear coordination of the Co(I) ions in Li2(Li1-xCox)N with two nitrogen ligands.	Nitrogen	103-111	ATP binding cassette subfamily A member 12	Homo sapiens	79-82
33733754-6	2021	Its microscopic origin is the unusual linear coordination of the Co(I) ions in Li2(Li1-xCox)N with two nitrogen ligands.	Nitrogen	103-111	transglutaminase 1	Homo sapiens	83-86
33755454-8	2021	Then, we investigated the reactivities of the (mu-eta2:eta2-NO2)dicopper complex toward methane and benzene by considering the conversions of N2O to N2 in the presence and the absence of methane or benzene.	Nitrogen	142-144	DNA polymerase iota	Homo sapiens	50-54
33755454-8	2021	Then, we investigated the reactivities of the (mu-eta2:eta2-NO2)dicopper complex toward methane and benzene by considering the conversions of N2O to N2 in the presence and the absence of methane or benzene.	Nitrogen	142-144	DNA polymerase iota	Homo sapiens	55-59
33755454-12	2021	The (mu-nitrosyl)dicopper complex then reacted with N2O to regenerate the (mu-eta2:eta2-NO2)dicopper complex and N2 with an activation barrier of 31.5 kcal/mol.	Nitrogen	52-54	DNA polymerase iota	Homo sapiens	78-82
33352790-7	2020	The further increase in CP level from 177 to 210 g/kg DM did not result in improved milk yield, but resulted in decreased milk N secretion and increased urinary N excretion.	Nitrogen	127-128	ceruloplasmin	Bos taurus	24-26
33316063-10	2021	Besides, INSR protein as an insulin receptor precursor showed a high potential site for posttranslation modifications, including phosphorylation and N-glycosylation.	Nitrogen	10-11	insulin receptor	Homo sapiens	28-44
33377107-1	2020	This protocol describes an integrated approach for analyzing site-specific N- and O-linked glycosylation of SARS-CoV-2 spike protein by mass spectrometry.	Nitrogen	75-76	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	119-124
33175093-0	2020	Translesion synthesis of the major nitrogen mustard-induced DNA lesion by human DNA polymerase eta.	Nitrogen	35-43	DNA polymerase eta	Homo sapiens	80-98
33755454-12	2021	The (mu-nitrosyl)dicopper complex then reacted with N2O to regenerate the (mu-eta2:eta2-NO2)dicopper complex and N2 with an activation barrier of 31.5 kcal/mol.	Nitrogen	52-54	DNA polymerase iota	Homo sapiens	83-87
18890100-0	1948	Effect of growth hormone on the nitrogen excretion and body weight of adult female rats.	Nitrogen	32-40	gonadotropin releasing hormone receptor	Rattus norvegicus	10-24
32363391-0	2020	Deducing the N- and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2.	Nitrogen	13-14	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	51-56
32363391-3	2020	The spike protein is comprised of two protein subunits (S1 and S2), which together possess 22 potential N-glycosylation sites.	Nitrogen	104-105	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	4-9
32363391-5	2020	We have characterized the quantitative N-glycosylation profile on spike protein and interestingly, observed unexpected O-glycosylation modifications on the receptor-binding domain of spike protein subunit S1.	Nitrogen	39-40	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	66-71
32363391-5	2020	We have characterized the quantitative N-glycosylation profile on spike protein and interestingly, observed unexpected O-glycosylation modifications on the receptor-binding domain of spike protein subunit S1.	Nitrogen	39-40	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	183-188
32363391-7	2020	Our data on the N- and O-glycosylation are strengthened by extensive manual interpretation of each glycopeptide spectra in addition to using bioinformatics tools to confirm the complexity of glycosylation in the spike protein.	Nitrogen	16-17	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	212-217
33660351-4	2021	Further, the SA maintains reliable adhesion on wet and cold substrates from 4 to -196  C and even tolerates splashing, violent shaking, and weight loading in liquid nitrogen (-196  C), showing promising applicability in cryogenic environments.	Nitrogen	165-173	acyl-CoA synthetase medium chain family member 3	Homo sapiens	13-15
18889800-0	1948	Effect of hypophyseal growth hormone upon the urinary nitrogen excretion of fasting rats.	Nitrogen	54-62	gonadotropin releasing hormone receptor	Rattus norvegicus	22-36
16744789-0	1931	The nitrogen metabolism of the lupin seedling.	Nitrogen	4-12	5'-nucleotidase, cytosolic IIIA	Homo sapiens	31-36
33478877-2	2021	The results indicated that, when the influent COD/TN ratio was 3.16, the advanced nitrogen removal was achieved with the effluent TN of 1.87 mg/L.	Nitrogen	82-90	C-type lectin domain family 3 member B	Homo sapiens	50-52
33478877-2	2021	The results indicated that, when the influent COD/TN ratio was 3.16, the advanced nitrogen removal was achieved with the effluent TN of 1.87 mg/L.	Nitrogen	82-90	C-type lectin domain family 3 member B	Homo sapiens	130-132
33478877-3	2021	Nitrogen removal by anammox accounted for 76% of TN removed in the EDA process.	Nitrogen	0-8	C-type lectin domain family 3 member B	Homo sapiens	49-51
33612237-13	2021	However, reducing dietary CP content resulted in a decrease in blood and milk urea-N concentrations, and urinary excretion of N and urea-N, suggestive of an improvement in the efficiency of N use.	Nitrogen	83-84	ceruloplasmin	Bos taurus	26-28
33612237-13	2021	However, reducing dietary CP content resulted in a decrease in blood and milk urea-N concentrations, and urinary excretion of N and urea-N, suggestive of an improvement in the efficiency of N use.	Nitrogen	126-127	ceruloplasmin	Bos taurus	26-28
33206527-10	2020	To investigate the regulatory effect of the N79 glycan on cellular growth, we mutated the single N-glycosylation site in CES1 from Asn to Gln (CES1-N79Q) via site-directed mutagenesis.	Nitrogen	44-45	carboxylesterase 1	Homo sapiens	121-125
33273096-5	2020	miR-223 restricts the EHT of lymphoid-myeloid lineages by suppressing the mannosyltransferase alg2 and sialyltransferase st3gal2, two enzymes involved in protein N-glycosylation.	Nitrogen	162-163	microRNA 223	Homo sapiens	0-7
33091421-6	2020	Then TRIM16 overexpression alleviated H2O2-induced oxidative stress by enhancing antioxidant capacity and reducing the amount of intracellular reactive oxygen species (ROS) and reactive nitrogen species (RNS).	Nitrogen	186-194	tripartite motif containing 16	Homo sapiens	5-11
16743141-0	1922	The Influence of Fat and Carbohydrate on the Nitrogen Distribution in the Urine.	Nitrogen	45-53	FAT atypical cadherin 1	Homo sapiens	17-20
33839389-7	2021	The amounts of F leaching-out from surface soils (0-25 cm) treated with nitrogen fertilizer decreased 1.03 kg ha-1 comparing with blank control.	Nitrogen	72-80	keratin 31	Homo sapiens	110-114
33930851-1	2021	Two novel nitrogen-enriched porous organic polymers (POPs), HBP and TBP, were constructed via nucleophilic substitution reactions with high nitrogen contents up to 24.91% and 32.92% for sensing to nitroaromatic compounds (NACs) and adsorbing iodine.	Nitrogen	10-18	heme binding protein 1	Homo sapiens	60-63
33827004-7	2021	Several hydrogen bonds and pi-stacking restrict the position of CPZ isomers in the active cavity of CYPs so that the 4"-nitrogen on the triazole ring can bind closely to the heme of CYP, which results in the metabolism of CPZ isomers.	Nitrogen	120-128	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	100-103
32980951-5	2020	Expression analysis of CLE1-CLE7 revealed that these genes respond to different environmental stimuli, such as nitrogen deprivation, nitrogen replenishment, cold, salt, dark, and sugar starvation, in a sophisticated manner.	Nitrogen	111-119	CLAVATA3/ESR-RELATED 1	Arabidopsis thaliana	23-27
32980951-5	2020	Expression analysis of CLE1-CLE7 revealed that these genes respond to different environmental stimuli, such as nitrogen deprivation, nitrogen replenishment, cold, salt, dark, and sugar starvation, in a sophisticated manner.	Nitrogen	133-141	CLAVATA3/ESR-RELATED 1	Arabidopsis thaliana	23-27
33930851-1	2021	Two novel nitrogen-enriched porous organic polymers (POPs), HBP and TBP, were constructed via nucleophilic substitution reactions with high nitrogen contents up to 24.91% and 32.92% for sensing to nitroaromatic compounds (NACs) and adsorbing iodine.	Nitrogen	140-148	heme binding protein 1	Homo sapiens	60-63
32946852-9	2020	Simply linear regression analysis indicated a negative association between serum Metrnl and duration of disease, body mass index (BMI), HbA1c, blood urea nitrogen, creatinine, uricacid, ACR, and angiotensin-converting enzyme inhibitor/angiotensin II receptor blockers treatment.	Nitrogen	154-162	meteorin like, glial cell differentiation regulator	Homo sapiens	81-87
33930851-5	2021	On the one hand, due to their excellent conjugated properties and nitrogen-enriched structures, HBP and TBP exhibited incredibly high sensitivity to m-dinitrobenzene (m-DNB) and picric acid (PA) with KSV values of 2.57 x 105 and 4.93 x 104 L mol-1 and limits of detection of 1.17 x 10-11 and 6.08 x 10-11 mol L-1, respectively.	Nitrogen	66-74	heme binding protein 1	Homo sapiens	96-99
33326655-1	2021	We present the synthesis and coordination chemistry of a bulky, tripodal N,N,O ligand, Im Ph2 NNO tBu ( L ), designed to model the 2-His-1-carboxylate facial triad (2H1C) by means of two imidazole groups and an anionic 2,4-di- tert -butyl-subtituted phenolate.	Nitrogen	73-74	viral integration site 1	Homo sapiens	133-138
33486685-5	2021	The NF (kg N cap-1 year-1) and PF (kg P cap-1 year-1) elevated from 5.56 and 1.20 in the 1960s to 15.2 and 4.79 during 2011-2017, respectively, while the national NF (Gg [109 g] N year-1) and national PF (Gg P year-1) increased from 27.7 and 6.77 in the 1960s to 358 and 122 during 2011-2017, respectively.	Nitrogen	4-5	cyclase associated actin cytoskeleton regulatory protein 1	Homo sapiens	13-18
33719895-9	2021	It identifies a new signaling axis, AMPK-NFE2L2-UQCRC2, in the regulation of mitophagy levels in the liver, suggesting a possible therapeutic strategy to treat ALD.Abbreviations: AAV: AENO-associated virus; ALD: alcoholic liver disease; AMPK: AMP-activated protein kinase; BUN: blood urea nitrogen; H&E: hematoxylin and eosin; CCCP: carbonyl cyanide 3-chlorophenylhydrazone; ChIP: chromatin immunoprecipitation assay; CO-IP: co-immunoprecipitation; COPD: chronic obstructive pulmonary disease; EM: electron microscope; GOT1/AST: glutamic-oxaloacetic transaminase 1; GPT/ALT: glutamic-pyruvic transaminase; IF: immunofluorescence; IHC: immunohistochemistry; KD: knockdown; MAP1LC3/LC3: microtubule associated protein 1 light chain protein 3; MTDR: MitoTracker Deep Red; NFE2L2/NRF2: nuclear factor, erythroid 2 like 2; mtDNA: mitochondrial DNA; MTRC: MitoTracker Red CMXRos; OCR: Oxygen consumption rate; OE: overexpress; PINK1: PTEN induced kinase 1; qRT-PCR: quantitative real-time PCR; ROS: reactive oxygen species; SD: standard deviation; SOD2: superoxide dismutase 2; UQCRC2: ubiquinol-cytochrome c reductase core protein 2; WB: western blot; DeltaPsi: mitochondrial membrane potential.	Nitrogen	289-297	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	36-40
32871382-3	2020	Here we analyzed 66 soil microbial communities from five FACE sites, and showed common microbial response patterns to eCO2, especially for key functional genes involved in carbon and nitrogen fixation (e.g., pcc/acc for carbon fixation, nifH for nitrogen fixation), carbon decomposition (e.g., amyA and pulA for labile carbon decomposition, mnp and lcc for recalcitrant carbon decomposition), and greenhouse gas emissions (e.g., mcrA for methane production, norB for nitrous oxide production) across five FACE sites.	Nitrogen	183-191	crystallin gamma D	Homo sapiens	208-211
34015941-11	2021	GSDMD and its pyroptosis-inducing N-terminal fragment (GSDMD-N) were upregulated in myocardial tissues after I/R injury.	Nitrogen	60-62	gasdermin D	Homo sapiens	0-5
33077685-0	2021	Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins.	Nitrogen	14-15	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	73-78
33066834-9	2020	Notch1 positive cell numbers were increased, whereas caspase-3 and TUNEL positive beta-cell numbers were decreased in n2-STZ + NA group.	Nitrogen	118-120	caspase 3	Rattus norvegicus	53-62
33655503-0	2021	N-glycosylation of the human neuropeptide QRFP receptor QRFPR is essential for ligand binding and receptor activation.	Nitrogen	0-1	pyroglutamylated RFamide peptide	Homo sapiens	42-46
33655503-0	2021	N-glycosylation of the human neuropeptide QRFP receptor QRFPR is essential for ligand binding and receptor activation.	Nitrogen	0-1	pyroglutamylated RFamide peptide receptor	Homo sapiens	56-61
33655503-3	2021	The human QRFP receptor QRFPR (GPR103) possesses three N-glycosylation consensus sites, two located on the N-terminal domain (N5 and N19) and one on the first extracellular loop (ECL1) (N106), however, to date, their role in QRFPR expression and signaling has not been established.	Nitrogen	55-56	pyroglutamylated RFamide peptide receptor	Homo sapiens	31-37
33655503-3	2021	The human QRFP receptor QRFPR (GPR103) possesses three N-glycosylation consensus sites, two located on the N-terminal domain (N5 and N19) and one on the first extracellular loop (ECL1) (N106), however, to date, their role in QRFPR expression and signaling has not been established.	Nitrogen	55-56	pyroglutamylated RFamide peptide receptor	Homo sapiens	24-29
33655503-7	2021	Analysis with confocal microscopy and quantitative ELISA showed that N-glycosylation of QRFPR is not essentially required for targeting to the cell membrane.	Nitrogen	69-70	pyroglutamylated RFamide peptide receptor	Homo sapiens	88-93
33655503-9	2021	Thus, our findings suggest that for the human QRFP receptor QRFPR, N-glycosylation is not important for cell surface expression but is a prerequisite for ligand binding and receptor activation.	Nitrogen	67-68	pyroglutamylated RFamide peptide	Homo sapiens	46-50
33655503-9	2021	Thus, our findings suggest that for the human QRFP receptor QRFPR, N-glycosylation is not important for cell surface expression but is a prerequisite for ligand binding and receptor activation.	Nitrogen	67-68	pyroglutamylated RFamide peptide receptor	Homo sapiens	60-65
33309857-6	2021	Mechanistically, we show that elevated p65 activity transcriptionally up-regulates B4GALT1 expression, which then interacts with and stabilizes cyclin dependent kinase 11 isomer CDK11p110 protein via N-linked glycosylation, in order to promote cancer progression and chemoresistance.	Nitrogen	200-201	RELA proto-oncogene, NF-kB subunit	Homo sapiens	39-42
33309857-6	2021	Mechanistically, we show that elevated p65 activity transcriptionally up-regulates B4GALT1 expression, which then interacts with and stabilizes cyclin dependent kinase 11 isomer CDK11p110 protein via N-linked glycosylation, in order to promote cancer progression and chemoresistance.	Nitrogen	200-201	cyclin dependent kinase 19	Homo sapiens	144-170
33428914-2	2021	From the perspective of nutrients removal performance, and the corresponding effluent total nitrogen (TN) and PO43--P in the calcinated pyrite autotrophic denitrification (CPAD) process decreased from 40.21 and 1.07 mg/L to 1.22 and 0.14 mg/L, respectively.	Nitrogen	92-100	C-type lectin domain family 3 member B	Homo sapiens	102-104
32556728-4	2020	This translocation of TrkB depends on co-factors and modulators of cAMP levels, N-glycosylation, and receptor transactivation.	Nitrogen	80-81	neurotrophic receptor tyrosine kinase 2	Homo sapiens	22-26
32623356-0	2020	N-glycosylation of High Mobility Group Box 1 protein (HMGB1) modulates the interaction with glycyrrhizin: A molecular modeling study.	Nitrogen	0-1	high mobility group box 1	Homo sapiens	19-44
32623356-0	2020	N-glycosylation of High Mobility Group Box 1 protein (HMGB1) modulates the interaction with glycyrrhizin: A molecular modeling study.	Nitrogen	0-1	high mobility group box 1	Homo sapiens	54-59
34058588-2	2021	Our study emphasizes revealing the mechanisms of chemical oxygen demand/total nitrogen (COD/TN) ratio dependent improved greywater (GW) treatment in an oxygen based membrane biofilm reactor (O2-MBfR).	Nitrogen	78-86	C-type lectin domain family 3 member B	Homo sapiens	92-94
32497822-5	2020	Total inputs of soil N in Chinese dryland soils were estimated at 121 kg N ha-1 in 2010, considering all pathways including N manure, fertilizer, atmospheric deposition and litter from crop residues.	Nitrogen	21-22	solute carrier family 9 member B1	Homo sapiens	73-79
32497822-7	2020	The highest ratio of NH3 volatilization to total N outputs was found at 43 kg N ha-1 (~21%) in Northern China, followed by 41 kg N ha-1 (~20%) in Sichuan Basin and 25 kg N ha-1 (~26%) in Northeastern China.	Nitrogen	21-22	solute carrier family 9 member B1	Homo sapiens	78-84
33608602-6	2021	Moreover, we demonstrated that activated ATM-deficient macrophages exhibit significantly elevated production of harmful reactive oxygen and nitrogen species and pro-inflammatory cytokines.	Nitrogen	140-148	ataxia telangiectasia mutated	Mus musculus	41-44
33960990-7	2021	We indicate the identified multidimensional path of N2 cleavage as an across edge-above surface (AEAS) mechanism: initially end-on coordinated N2 bends towards a neighboring Ta-atom which yields a second intermediate, with a mu2 bonded N2 across an edge of the Ta4+ tetrahedron core.	Nitrogen	52-54	adaptor related protein complex 1 subunit mu 2	Homo sapiens	225-228
33128336-2	2021	Here, via a controllable NH 3 treatment, we construct sandwiched p-n homojunctions in three-unit-cells n-type SnS 2 (n-SnS 2 ) nanosheet arrays using nitrogen (N) as acceptor dopants.	Nitrogen	14-15	sodium voltage-gated channel alpha subunit 11	Homo sapiens	110-115
33128336-2	2021	Here, via a controllable NH 3 treatment, we construct sandwiched p-n homojunctions in three-unit-cells n-type SnS 2 (n-SnS 2 ) nanosheet arrays using nitrogen (N) as acceptor dopants.	Nitrogen	14-15	sodium voltage-gated channel alpha subunit 11	Homo sapiens	119-124
32823246-4	2020	The accumulation of sorbitol and sucrose in the fine roots was higher, and the activities of sucrose synthase, invertase and sorbitol dehydrogenase, which are involved in the degradation of sucrose and sorbitol, were significantly increased under a low nitrogen supply.	Nitrogen	253-261	sorbitol dehydrogenase-like	Malus domestica	111-147
33128336-2	2021	Here, via a controllable NH 3 treatment, we construct sandwiched p-n homojunctions in three-unit-cells n-type SnS 2 (n-SnS 2 ) nanosheet arrays using nitrogen (N) as acceptor dopants.	Nitrogen	150-158	sodium voltage-gated channel alpha subunit 11	Homo sapiens	110-115
31851120-2	2020	A single nucleotide polymorphism (SNP rs1130866) of human SP-B (hSP-B) alters the N-linked glycosylation, thus presumably affecting SP-B function.	Nitrogen	35-36	surfactant protein B	Homo sapiens	58-62
33128336-2	2021	Here, via a controllable NH 3 treatment, we construct sandwiched p-n homojunctions in three-unit-cells n-type SnS 2 (n-SnS 2 ) nanosheet arrays using nitrogen (N) as acceptor dopants.	Nitrogen	25-26	sodium voltage-gated channel alpha subunit 11	Homo sapiens	110-115
31851120-2	2020	A single nucleotide polymorphism (SNP rs1130866) of human SP-B (hSP-B) alters the N-linked glycosylation, thus presumably affecting SP-B function.	Nitrogen	35-36	surfactant protein B	Homo sapiens	64-69
33128336-2	2021	Here, via a controllable NH 3 treatment, we construct sandwiched p-n homojunctions in three-unit-cells n-type SnS 2 (n-SnS 2 ) nanosheet arrays using nitrogen (N) as acceptor dopants.	Nitrogen	25-26	sodium voltage-gated channel alpha subunit 11	Homo sapiens	119-124
33960990-7	2021	We indicate the identified multidimensional path of N2 cleavage as an across edge-above surface (AEAS) mechanism: initially end-on coordinated N2 bends towards a neighboring Ta-atom which yields a second intermediate, with a mu2 bonded N2 across an edge of the Ta4+ tetrahedron core.	Nitrogen	52-54	trace amine associated receptor 6	Homo sapiens	261-264
33128336-3	2021	The optimal N-doped n-SnS 2 (pnp-SnS 2 ) with such unique structure achieves a record photocurrent density of 3.28 mA cm -2 , which is 21 times as high as that of n-SnS 2 and the highest value among all the SnS 2 photoanodes reported so far.	Nitrogen	12-13	sodium voltage-gated channel alpha subunit 11	Homo sapiens	22-27
33128336-3	2021	The optimal N-doped n-SnS 2 (pnp-SnS 2 ) with such unique structure achieves a record photocurrent density of 3.28 mA cm -2 , which is 21 times as high as that of n-SnS 2 and the highest value among all the SnS 2 photoanodes reported so far.	Nitrogen	12-13	sodium voltage-gated channel alpha subunit 11	Homo sapiens	33-38
31851120-2	2020	A single nucleotide polymorphism (SNP rs1130866) of human SP-B (hSP-B) alters the N-linked glycosylation, thus presumably affecting SP-B function.	Nitrogen	35-36	surfactant protein B	Homo sapiens	65-69
33014431-1	2020	ALG13 (asparagine-linked glycosylation 13) plays crucial roles in the process of N-linked glycosylation.	Nitrogen	81-82	asparagine-linked glycosylation 13	Mus musculus	0-5
33014431-1	2020	ALG13 (asparagine-linked glycosylation 13) plays crucial roles in the process of N-linked glycosylation.	Nitrogen	81-82	asparagine-linked glycosylation 13	Mus musculus	7-41
33128336-3	2021	The optimal N-doped n-SnS 2 (pnp-SnS 2 ) with such unique structure achieves a record photocurrent density of 3.28 mA cm -2 , which is 21 times as high as that of n-SnS 2 and the highest value among all the SnS 2 photoanodes reported so far.	Nitrogen	12-13	sodium voltage-gated channel alpha subunit 11	Homo sapiens	33-38
33128336-3	2021	The optimal N-doped n-SnS 2 (pnp-SnS 2 ) with such unique structure achieves a record photocurrent density of 3.28 mA cm -2 , which is 21 times as high as that of n-SnS 2 and the highest value among all the SnS 2 photoanodes reported so far.	Nitrogen	12-13	sodium voltage-gated channel alpha subunit 11	Homo sapiens	33-38
33090600-2	2021	The posttranslational N-glycosylation of Asn31 of MOG seems to play a key role in modulating the immune response towards myelin.	Nitrogen	22-23	myelin oligodendrocyte glycoprotein	Homo sapiens	50-53
33960990-7	2021	We indicate the identified multidimensional path of N2 cleavage as an across edge-above surface (AEAS) mechanism: initially end-on coordinated N2 bends towards a neighboring Ta-atom which yields a second intermediate, with a mu2 bonded N2 across an edge of the Ta4+ tetrahedron core.	Nitrogen	143-145	adaptor related protein complex 1 subunit mu 2	Homo sapiens	225-228
33960990-7	2021	We indicate the identified multidimensional path of N2 cleavage as an across edge-above surface (AEAS) mechanism: initially end-on coordinated N2 bends towards a neighboring Ta-atom which yields a second intermediate, with a mu2 bonded N2 across an edge of the Ta4+ tetrahedron core.	Nitrogen	143-145	trace amine associated receptor 6	Homo sapiens	261-264
33960990-7	2021	We indicate the identified multidimensional path of N2 cleavage as an across edge-above surface (AEAS) mechanism: initially end-on coordinated N2 bends towards a neighboring Ta-atom which yields a second intermediate, with a mu2 bonded N2 across an edge of the Ta4+ tetrahedron core.	Nitrogen	143-145	adaptor related protein complex 1 subunit mu 2	Homo sapiens	225-228
33264956-2	2021	In this study, contamination with OTC and Cu alone or in combination reduced the total nitrogen (TN) content of the fermentation products.	Nitrogen	87-95	C-type lectin domain family 3 member B	Homo sapiens	97-99
32699088-10	2020	Sequence analyses of the influenza A virus (IAV) surface antigen neuraminidase (NA or N) showed that the conservation of N-linked glycosylation sites on the NA enzymatic head domain differs by IAV subtype (H1N1 vs H3N2) and species of origin, with human derived IAVs possessing the most variability.	Nitrogen	80-81	neuraminidase 1	Homo sapiens	65-78
33960990-7	2021	We indicate the identified multidimensional path of N2 cleavage as an across edge-above surface (AEAS) mechanism: initially end-on coordinated N2 bends towards a neighboring Ta-atom which yields a second intermediate, with a mu2 bonded N2 across an edge of the Ta4+ tetrahedron core.	Nitrogen	143-145	trace amine associated receptor 6	Homo sapiens	261-264
33345499-10	2020	Soil pH was significantly reduced after three years nitrogen addition, and AcP activitiy was significantly increased after 10 years nitrogen addition.	Nitrogen	52-60	phenylalanine hydroxylase	Homo sapiens	5-7
33345499-13	2020	The significant negative correlation between soil pH and AcP activity indicated that change in soil pH caused by nitrogen addition may be an important factor for the variation of soil phosphatase activity.	Nitrogen	113-121	phenylalanine hydroxylase	Homo sapiens	50-52
33960990-11	2021	We recognize that substoichiometric N2 exposure allows for spontaneous activation by Ta4+, while higher N2 exposure causes self-poisoning.	Nitrogen	36-38	trace amine associated receptor 6	Homo sapiens	85-88
33345499-13	2020	The significant negative correlation between soil pH and AcP activity indicated that change in soil pH caused by nitrogen addition may be an important factor for the variation of soil phosphatase activity.	Nitrogen	113-121	phenylalanine hydroxylase	Homo sapiens	100-102
33976130-0	2021	FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer.	Nitrogen	23-24	fucosyltransferase 8	Homo sapiens	0-4
32788233-4	2020	Conversely, deletion of pef1 leads to activation of autophagy and subsequent excessive TORC1 reactivation during the early phases of the nitrogen starvation response.	Nitrogen	137-145	penta-EF-hand domain containing 1	Homo sapiens	24-28
32788233-4	2020	Conversely, deletion of pef1 leads to activation of autophagy and subsequent excessive TORC1 reactivation during the early phases of the nitrogen starvation response.	Nitrogen	137-145	CREB regulated transcription coactivator 1	Homo sapiens	87-92
33976130-0	2021	FUT8-mediated aberrant N-glycosylation of B7H3 suppresses the immune response in triple-negative breast cancer.	Nitrogen	23-24	CD276 molecule	Homo sapiens	42-46
33976130-4	2021	Here, we identify aberrant B7H3 glycosylation and show that N-glycosylation of B7H3 at NXT motif sites is responsible for its protein stability and immunosuppression in TNBC tumors.	Nitrogen	60-61	CD276 molecule	Homo sapiens	79-83
33976130-4	2021	Here, we identify aberrant B7H3 glycosylation and show that N-glycosylation of B7H3 at NXT motif sites is responsible for its protein stability and immunosuppression in TNBC tumors.	Nitrogen	60-61	nuclear transport factor 2 like export factor 1	Homo sapiens	87-90
33878865-4	2021	To further promote N2 activation, we develop a simple protocol to introduce and adjust the crystal defects in the host lattice of Bi2WO6 nanoflowers via adjusting the amount of Ce dopant (denoted as xCe-Bi2WO6, where x represents the designed mole percentage of Ce).	Nitrogen	19-21	X chromosome inactivation center	Homo sapiens	199-202
32642835-2	2020	They are heterodimers sharing the alpha-subunit structure that has 2 N-glycosylation sites.	Nitrogen	69-70	hyaluronan synthase 2	Homo sapiens	63-68
33758916-3	2021	Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3.	Nitrogen	10-11	nitrate transporter2.5	Arabidopsis thaliana	187-193
30888252-7	2020	In addition, the growth of internal pores in AACP promoted the removal of phosphorus and nitrogen.	Nitrogen	89-97	N-acetyltransferase pseudogene	Homo sapiens	45-49
33758916-3	2021	Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3.	Nitrogen	43-51	nitrate transporter2.5	Arabidopsis thaliana	187-193
33758916-3	2021	Following N removal, plants activate their Nitrogen Starvation Response (NSR) being characterized in particular by the activation of very high-affinity nitrate transport systems (NRT2.4, NRT2.5) and other sentinel genes involved in N-remobilization such as GDH3.	Nitrogen	43-44	nitrate transporter2.5	Arabidopsis thaliana	187-193
33908218-14	2021	Knockdown of MIR210HG decreased blood urea nitrogen, serum creatinine, and proinflammatory cytokine levels in AKI rats.	Nitrogen	43-51	MIR210 host gene	Homo sapiens	13-21
32693188-10	2020	In macrophages, expression of LACC1 was required for toll like receptor-induced uptake of bacteria, which required PDK1, and MAPK- and nuclear factor kappaB-dependent induction of reactive oxygen species, reactive nitrogen species, and autophagy.	Nitrogen	214-222	laccase domain containing 1	Mus musculus	30-35
31659629-12	2020	In contrast, IL-1-induced alpha-ENaC protein levels were unaffected by a c-Jun N-terminal kinase (JNK) inhibitor.	Nitrogen	33-34	interleukin 1 complex	Mus musculus	13-17
33872022-3	2021	Here, we report on a deep subwavelength nonlinear antenna based on dilute nitride GaNP nanowires (NWs), whose second harmonic generation (SHG) shows a 5-fold increase by incorporating ~0.45% of nitrogen (N), in comparison with GaP counterpart.	Nitrogen	194-202	minichromosome maintenance complex component 3 associated protein	Homo sapiens	82-86
32035922-5	2020	We identified several IkappaBzeta phosphorylation sites, including a conserved cluster of threonine residues located in the N-terminus of the protein, which can be phosphorylated by MAPKs.	Nitrogen	124-125	NFKB inhibitor zeta	Homo sapiens	22-33
33830722-0	2021	SnS2 Nanosheets Anchored on Nitrogen and Sulfur Co-Doped MXene Sheets for High-Performance Potassium-Ion Batteries.	Nitrogen	28-36	sodium voltage-gated channel alpha subunit 11	Homo sapiens	0-4
32388863-6	2020	RESULTS: Nitrogen transformation from FAU and PAU was slowed down compared with urea.	Nitrogen	9-17	FAU ubiquitin like and ribosomal protein S30 fusion	Homo sapiens	38-41
33830722-3	2021	Herein, SnS2 nanosheets anchored on nitrogen and sulfur co-doped MXene (SnS2 NSs/MXene) are creatively designed as advanced anode materials for KIBs.	Nitrogen	36-44	sodium voltage-gated channel alpha subunit 11	Homo sapiens	8-12
33883138-2	2021	Here, we report a previously unknown function for the hepatic FXR-SHP axis in controlling protein N-linked glycosylation.	Nitrogen	98-99	nuclear receptor subfamily 1 group H member 4	Homo sapiens	62-65
32817462-3	2020	We hypothesized that NO or derivative reactive nitrogen species may generate adducts of tyrosine and/or cysteine residues, causing CYP2B6 downregulation, and selected Tyr and Cys residues for mutation based on predicted solvent accessibility.	Nitrogen	47-55	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	131-137
32824661-0	2020	Nitrogen-Enriched Cr1-xAlxN Multilayer-Like Coatings Manufactured by Dynamic Glancing Angle Direct Current Magnetron Sputtering.	Nitrogen	0-8	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	18-21
33883138-2	2021	Here, we report a previously unknown function for the hepatic FXR-SHP axis in controlling protein N-linked glycosylation.	Nitrogen	98-99	nuclear receptor subfamily 0 group B member 2	Homo sapiens	66-69
33608284-7	2021	Soybean genes GmRIC1 and GmRIC2, involved in autoregulation of nodulation, were upregulated in plants inoculated with the mutant in N-free condition.	Nitrogen	132-133	CLE-related protein RIC1	Glycine max	14-20
32628023-3	2020	Taking an example of SnS2 precursors, the final-obtained surface N enriched Sn(S) nanosheets (denoted as N-Sn(S) nanosheets) exhibit a 5-fold of current density and 2.45-fold of Faradaic efficiency than pristine SnS2 derived Sn(S) nanosheets (denoted as Sn(S) nanosheets).	Nitrogen	65-66	sodium voltage-gated channel alpha subunit 11	Homo sapiens	21-25
32628023-3	2020	Taking an example of SnS2 precursors, the final-obtained surface N enriched Sn(S) nanosheets (denoted as N-Sn(S) nanosheets) exhibit a 5-fold of current density and 2.45-fold of Faradaic efficiency than pristine SnS2 derived Sn(S) nanosheets (denoted as Sn(S) nanosheets).	Nitrogen	65-66	sodium voltage-gated channel alpha subunit 11	Homo sapiens	212-216
33608284-7	2021	Soybean genes GmRIC1 and GmRIC2, involved in autoregulation of nodulation, were upregulated in plants inoculated with the mutant in N-free condition.	Nitrogen	132-133	CLE-related protein RIC2	Glycine max	25-31
33837815-1	2021	A growing body of evidence suggests that Nod Factors molecules are the critical structural components in nitrogen fixation.	Nitrogen	105-113	atrophin 1	Homo sapiens	41-44
32753694-10	2020	For an NNI value equal to 1, the nitrogen application level required was 224.07 kg hm-2 for ZH 311 and 283.01 kg hm-2 for XY 508, indicating that the suitable application rate for the nitrogen-efficient cultivar is lower than that for the nitrogen-inefficient cultivar.	Nitrogen	33-41	Putative anthocyanidin reductase	Zea mays	83-87
32753694-10	2020	For an NNI value equal to 1, the nitrogen application level required was 224.07 kg hm-2 for ZH 311 and 283.01 kg hm-2 for XY 508, indicating that the suitable application rate for the nitrogen-efficient cultivar is lower than that for the nitrogen-inefficient cultivar.	Nitrogen	33-41	Putative anthocyanidin reductase	Zea mays	113-117
32753694-10	2020	For an NNI value equal to 1, the nitrogen application level required was 224.07 kg hm-2 for ZH 311 and 283.01 kg hm-2 for XY 508, indicating that the suitable application rate for the nitrogen-efficient cultivar is lower than that for the nitrogen-inefficient cultivar.	Nitrogen	184-192	Putative anthocyanidin reductase	Zea mays	83-87
32753694-10	2020	For an NNI value equal to 1, the nitrogen application level required was 224.07 kg hm-2 for ZH 311 and 283.01 kg hm-2 for XY 508, indicating that the suitable application rate for the nitrogen-efficient cultivar is lower than that for the nitrogen-inefficient cultivar.	Nitrogen	184-192	Putative anthocyanidin reductase	Zea mays	113-117
32753694-10	2020	For an NNI value equal to 1, the nitrogen application level required was 224.07 kg hm-2 for ZH 311 and 283.01 kg hm-2 for XY 508, indicating that the suitable application rate for the nitrogen-efficient cultivar is lower than that for the nitrogen-inefficient cultivar.	Nitrogen	184-192	Putative anthocyanidin reductase	Zea mays	83-87
32240040-9	2021	Tps2 regulates nuclear translocation and activation of Rim15 kinase, a negative regulator of Ume6, by causing the dissociation of Rim15 from the 14-3-3 proteins Bmh1/2 under nitrogen starvation, suggesting that Rim15 mediates the function of Tps2 as a positive regulator of ATG8 induction.	Nitrogen	174-182	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	93-97
32753694-10	2020	For an NNI value equal to 1, the nitrogen application level required was 224.07 kg hm-2 for ZH 311 and 283.01 kg hm-2 for XY 508, indicating that the suitable application rate for the nitrogen-efficient cultivar is lower than that for the nitrogen-inefficient cultivar.	Nitrogen	184-192	Putative anthocyanidin reductase	Zea mays	113-117
33551170-0	2021	Variations in N-linked glycosylation of glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) whey protein: Intercow differences and dietary effects.	Nitrogen	14-15	glycosylation dependent cell adhesion molecule 1	Bos taurus	40-88
32430722-4	2020	Glutamate dehydrogenase (GDH) activity was generally enhanced, accompanied by increases of 0.4- to 1.9-fold in proline levels, revealing GDH as an important compensatory route for both N assimilation and proline production under stressful conditions.	Nitrogen	185-186	glutamate dehydrogenase	Solanum lycopersicum	0-23
32430722-4	2020	Glutamate dehydrogenase (GDH) activity was generally enhanced, accompanied by increases of 0.4- to 1.9-fold in proline levels, revealing GDH as an important compensatory route for both N assimilation and proline production under stressful conditions.	Nitrogen	185-186	glutamate dehydrogenase	Solanum lycopersicum	25-28
33551170-0	2021	Variations in N-linked glycosylation of glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) whey protein: Intercow differences and dietary effects.	Nitrogen	14-15	glycosylation dependent cell adhesion molecule 1	Bos taurus	90-98
32430722-4	2020	Glutamate dehydrogenase (GDH) activity was generally enhanced, accompanied by increases of 0.4- to 1.9-fold in proline levels, revealing GDH as an important compensatory route for both N assimilation and proline production under stressful conditions.	Nitrogen	185-186	glutamate dehydrogenase	Solanum lycopersicum	137-140
32742386-9	2020	Expression of C"s C was positively correlated with urea nitrogen and creatinine (P<0.05).	Nitrogen	56-64	cystatin C	Homo sapiens	14-19
33372353-3	2021	Herein, we report a function-oriented strategy of deliberately constructing black phosphorus quantum dots-ZnIn 2 S 4 (BP/ZIS) heterostructures for solar-driven CO 2 reduction to syngas paired with selectively oxidative C-N bond formation in one redox cycle.	Nitrogen	221-222	zinc finger RANBP2-type containing 2	Homo sapiens	121-124
31810616-15	2020	Conversely, N (1313 +-315 mum2) and Z (735 +-126 mum2) groups showed significantly higher wear rate on the hexagon of external implants.	Nitrogen	12-13	WT1 associated protein	Homo sapiens	26-30
33734437-7	2021	We provide evidence that ALG13 pathogenic variants may mildly alter N-linked protein glycosylation in both female and male subjects, but the underlying mechanism remains unclear.	Nitrogen	68-69	ALG13 UDP-N-acetylglucosaminyltransferase subunit	Homo sapiens	25-30
32793580-6	2020	Ras GTPase Ras2, a stimulator of cAMP production, is a key factor for achieving fermentation, and is also relevant for sensing nitrogen availability.	Nitrogen	127-135	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	11-15
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	DNA polymerase iota	Homo sapiens	134-138
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	DNA polymerase iota	Homo sapiens	174-178
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	DNA polymerase iota	Homo sapiens	174-178
33678121-3	2021	This pathway is activated in response to nitrogen starvation and recycles transcriptional activators (Msn2 and Rim15) and a repressor (Ssn2/Med13) of ATG expression.	Nitrogen	41-49	mediator complex subunit 13	Homo sapiens	140-145
32635192-0	2020	The HSP90 Inhibitor, AUY-922, Ameliorates the Development of Nitrogen Mustard-Induced Pulmonary Fibrosis and Lung Dysfunction in Mice.	Nitrogen	61-69	heat shock protein, 3	Mus musculus	4-9
32635192-2	2020	Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung injury driven by TNF-alpha, TGF-beta, ERK and HSP90.	Nitrogen	29-37	heat shock protein, 3	Mus musculus	143-148
33127052-0	2021	Enriched oxygen vacancies of Cu2O/SnS2/SnO2 heterostructure for enhanced photocatalytic reduction of CO2 by water and nitrogen fixation.	Nitrogen	118-126	sodium voltage-gated channel alpha subunit 11	Homo sapiens	34-38
32109505-0	2020	N-glycosylation state of TRPM8 protein revealed by terahertz spectroscopy and molecular modelling.	Nitrogen	0-1	transient receptor potential cation channel subfamily M member 8	Homo sapiens	25-30
32109505-3	2020	TRPM8 is N-glycosylated, with a single site per subunit.	Nitrogen	9-10	transient receptor potential cation channel subfamily M member 8	Homo sapiens	0-5
32109505-4	2020	This work focuses on the N-glycosylation of TRPM8 channel that was previously studied by our group in relation to proliferation and migration of tumoral cells.	Nitrogen	25-26	transient receptor potential cation channel subfamily M member 8	Homo sapiens	44-49
33754559-2	2021	The results showed that across the two years CN-CCC increased maize yield by 7.7% and 5.0% under the nitrogen application rates of 62.5 kg hm-2 and 125 kg hm-2, respectively.	Nitrogen	101-109	Putative anthocyanidin reductase	Zea mays	139-143
32305506-6	2020	We decided to use the analogy of a play and speculate about the possible impact in this tragedy of 1) air pollution via the interference of nitrogen dioxide on ACE2 expression; 2) the dual role of nicotine; 3) the hypothetical involvement of ACE2 polymorphisms, the relationships of which with ethnic factors and susceptibility to cardiovascular disease seems intriguing; 4) the impact on the severity of infection of hypertension and related medications acting on the renin/angiotensin system, and, finally, 5) the possible helpful role of chloroquine, thanks to its capacity of modifying ACE2 affinity to the viral spike protein by altering glycosylation.	Nitrogen	140-148	angiotensin converting enzyme 2	Homo sapiens	160-164
32602601-1	2021	IN THIS STUDY, THE EU-DOPED LI2(BA1-XSRX)SIO4 POWDERS (X=0, 0.2, 0.4, AND 0.6) WERE SYNTHESIZED AT 850OC IN A REDUCTION ATMOSPHERE (5% H2 + 95% N2) FOR A DURATION OF 1 H THROUGH THE SOLID-STATE REACTION METHOD.	Nitrogen	144-146	ATP binding cassette subfamily A member 12	Homo sapiens	28-31
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	25-33	Putative anthocyanidin reductase	Zea mays	66-70
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	25-33	Putative anthocyanidin reductase	Zea mays	82-86
32990332-2	2021	The NNBCO complex rearranges to the ( eta 2 -N 2 )BCO isomer with a more activated side-on bonded dinitrogen ligand upon visible light excitation.	Nitrogen	98-108	DNA polymerase iota	Homo sapiens	38-43
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	95-103	Putative anthocyanidin reductase	Zea mays	82-86
32990332-3	2021	( eta 2 -N 2 )BCO and its weakly CO-coordinated complexes further isomerize to the NBNCO and B(NCO) 2 molecules with N-N bond being completely cleaved under UV light irradiation.	Nitrogen	9-10	DNA polymerase iota	Homo sapiens	2-7
32990332-3	2021	( eta 2 -N 2 )BCO and its weakly CO-coordinated complexes further isomerize to the NBNCO and B(NCO) 2 molecules with N-N bond being completely cleaved under UV light irradiation.	Nitrogen	83-84	DNA polymerase iota	Homo sapiens	2-7
32285534-5	2020	As a result, nitrogen cycling reduces projected land carbon uptake for the years 2006-2099 by 19% (37% decrease to 3% increase) for RCP 2.6, and by 21% (40% decrease to 9% increase) for RCP 8.5.	Nitrogen	13-21	CGRP receptor component	Homo sapiens	132-135
32285534-5	2020	As a result, nitrogen cycling reduces projected land carbon uptake for the years 2006-2099 by 19% (37% decrease to 3% increase) for RCP 2.6, and by 21% (40% decrease to 9% increase) for RCP 8.5.	Nitrogen	13-21	CGRP receptor component	Homo sapiens	186-189
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	95-103	Putative anthocyanidin reductase	Zea mays	82-86
32285534-6	2020	Most of the ensemble spread results from uncertainty in temperate and boreal forests, and is dominated by uncertainty in biological nitrogen fixation (10% decrease to 50% increase for RCP 2.6, 5% decrease to 100% increase for RCP 8.5).	Nitrogen	132-140	CGRP receptor component	Homo sapiens	184-187
32285534-6	2020	Most of the ensemble spread results from uncertainty in temperate and boreal forests, and is dominated by uncertainty in biological nitrogen fixation (10% decrease to 50% increase for RCP 2.6, 5% decrease to 100% increase for RCP 8.5).	Nitrogen	132-140	CGRP receptor component	Homo sapiens	226-229
32398320-5	2020	Besides DWF1, low N also upregulates other central BR biosynthesis genes including CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD), DWARF 4 (DWF4) and BRASSINOSTEROID-6-OXIDASE 2 (BR6OX2).	Nitrogen	18-19	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	145-172
32398320-5	2020	Besides DWF1, low N also upregulates other central BR biosynthesis genes including CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD), DWARF 4 (DWF4) and BRASSINOSTEROID-6-OXIDASE 2 (BR6OX2).	Nitrogen	18-19	brassinosteroid-6-oxidase 2	Arabidopsis thaliana	174-180
32758998-6	2021	Its magnificent mesoporous nature was revealed from BET (nitrogen adsorption-desorption measurements) analysis.	Nitrogen	57-65	delta/notch like EGF repeat containing	Homo sapiens	52-55
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	95-103	Putative anthocyanidin reductase	Zea mays	82-86
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	95-103	Putative anthocyanidin reductase	Zea mays	82-86
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	95-103	Putative anthocyanidin reductase	Zea mays	82-86
33754559-4	2021	Under the low and middle nitrogen application conditions (62.5 kg hm-2 and 125 kg hm-2), plant nitrogen content of JNK728 and ZD909 increased by 17.6% and 30.3%, grain nitrogen content increased by 10.3% and 17.4%, nitrogen partial productivity, agronomic efficiency of applied nitrogen, recovery efficiency of applied nitrogen, nitrogen use efficiency increased by 10.0%, 15.7%, 23.3%, 24.8% and 5.7%, 15.0%, 49.9%, 71.7%, respectively.	Nitrogen	95-103	Putative anthocyanidin reductase	Zea mays	82-86
32610141-5	2020	We show in cells, human specimens, and mouse xenografts that proteome connectivity is restorable by inhibition of the N-glycosylated GRP94 variant.	Nitrogen	118-119	heat shock protein 90, beta (Grp94), member 1	Mus musculus	133-138
33754559-6	2021	Our results showed that CCC combined basic nitrogen application of 125 kg hm-2 had the best effect.	Nitrogen	43-51	Putative anthocyanidin reductase	Zea mays	74-78
33652868-3	2021	The permanent porosity of 1 was confirmed by N2, O2, CO, CO2, CH4 adsorption measurements at various temperatures (77 K, 273 K, 298 K), resulted in BET surface area 667 m2 g-1 and promising gas separation performance with selectivity factors up to 35.7 for CO2/N2, 45.4 for CO2/O2, 20.8 for CO2/CO, and 4.8 for CO2/CH4.	Nitrogen	45-47	delta/notch like EGF repeat containing	Homo sapiens	148-151
32560750-3	2020	This review focuses on the development of bioinspired facial N,N,O ligands that model the 2-His-1-Carboxylate facial triad to a greater degree of structural accuracy than many of the polydentate N-donor ligands commonly used in this field.	Nitrogen	61-62	viral integration site 1	Homo sapiens	92-97
33560846-1	2021	In low-temperature flash photolysis of NH3/O2/N2 mixtures, the NH2 consumption rate and the product distribution is controlled by the reactions NH2 + HO2   products (R1), NH2 + H (+M)   NH3 (+M) (R2), and NH2 + NH2 (+M)   N2H4 (+M) (R3).	Nitrogen	46-48	heme oxygenase 2	Homo sapiens	150-153
33631788-0	2021	Organic nitrogen nutrition: LHT1.2 protein from hybrid aspen (Populus tremula L. x tremuloides Michx) is a functional amino acid transporter and a homolog of Arabidopsis LHT1.	Nitrogen	8-16	lysine histidine transporter 1	Arabidopsis thaliana	28-32
32376684-2	2020	Several EOGT mutations that may affect putative N-glycosylation consensus sites are recorded in the cancer database, but the presence and function of N-glycans in EOGT have not yet been characterized.	Nitrogen	48-49	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	8-12
32376684-4	2020	Three predicted N-glycosylation consensus sequences on EOGT are highly conserved among mammalian species.	Nitrogen	16-17	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	55-59
32376684-8	2020	However, simultaneous substitution of both N-glycosylation sites affected both EOGT maturation and expression levels without an apparent change in enzymatic activity, suggesting that N-glycosylation at a single site is sufficient for EOGT maturation and expression.	Nitrogen	43-44	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	79-83
32376684-8	2020	However, simultaneous substitution of both N-glycosylation sites affected both EOGT maturation and expression levels without an apparent change in enzymatic activity, suggesting that N-glycosylation at a single site is sufficient for EOGT maturation and expression.	Nitrogen	43-44	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	234-238
33631788-10	2021	Thus, we identified a functional AtLHT1 homolog in hybrid aspen, which harbors the potential to enhance overall plant N levels and hence increase biomass production.	Nitrogen	118-119	lysine histidine transporter 1	Arabidopsis thaliana	33-39
32376684-8	2020	However, simultaneous substitution of both N-glycosylation sites affected both EOGT maturation and expression levels without an apparent change in enzymatic activity, suggesting that N-glycosylation at a single site is sufficient for EOGT maturation and expression.	Nitrogen	183-184	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	234-238
32376684-10	2020	Moreover, the N263Q/N354Q variant exhibited altered subcellular distribution within the ER in HEK293T cells, indicating that N-glycosylation of EOGT is required for its ER localization at the cell periphery.	Nitrogen	14-15	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	144-148
33617879-5	2021	Here, we show that functionalization of the 4-arylidene position of the fluorescent curcumin scaffold with an aryl nitrogen mustard provides a stable Hck inhibitor (Kd = 50 +- 10 nM).	Nitrogen	115-123	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	150-153
32202031-6	2020	These include NifS and NifU, found primarily in aerobic species, suggesting that these genes are necessary for accommodating the high demand for Fe-S clusters during aerobic nitrogen fixation.	Nitrogen	174-182	NFS1 cysteine desulfurase	Homo sapiens	14-18
32577017-0	2020	Dkk3/REIC, an N-glycosylated Protein, Is a Physiological Endoplasmic Reticulum Stress Inducer in the Mouse Adrenal Gland.	Nitrogen	14-15	dickkopf WNT signaling pathway inhibitor 3	Mus musculus	0-4
32577017-3	2020	To determine the functions of Dkk3 in the mouse adrenal gland, we first identified that the mouse Dkk3 protein is N-glycosylated in the adrenal gland as well as in the brain.	Nitrogen	114-115	dickkopf WNT signaling pathway inhibitor 3	Mus musculus	30-34
33604622-7	2021	The findings provide insight into the regulation of maize GDH activity by ammonium and potassium and reveal the importance of the dose and ratio of nitrogen and potassium in crop cultivation.	Nitrogen	148-156	glutamic dehydrogenase1	Zea mays	58-61
31558672-2	2020	Although it has been established that the FVIII binding site resides in the N-terminal D"-D3 domains of Von Willebrand Factor, detailed information about the amino acid regions that contribute to FVIII binding is still lacking.	Nitrogen	76-77	coagulation factor VIII	Homo sapiens	42-47
33272657-4	2021	It was concluded that under varying HRT conditions, the decrease in effluent pH did not indicate the deterioration of nitrogen removal, but did indicate that the nitrogen removal efficiency was reduced owing to a sudden increase in the nitrogen loading rate resulting from the decrease in HRT.	Nitrogen	162-170	phenylalanine hydroxylase	Homo sapiens	77-79
32724637-3	2020	The results showed that the addition of encapsulated TGase significantly (p   .05) increased protein and fat content, dry matter, nitrogen recovery, and pH, as well as the production yield of cheeses.	Nitrogen	130-138	transglutaminase 1	Homo sapiens	53-58
33272657-4	2021	It was concluded that under varying HRT conditions, the decrease in effluent pH did not indicate the deterioration of nitrogen removal, but did indicate that the nitrogen removal efficiency was reduced owing to a sudden increase in the nitrogen loading rate resulting from the decrease in HRT.	Nitrogen	162-170	phenylalanine hydroxylase	Homo sapiens	77-79
33578954-5	2021	Removal of the N-glycosylation sites on the I-like domain of integrin beta1 (termed the Delta4-6 beta1 mutant) suppressed focal adhesion kinase (FAK) signaling, cell migration, and adhesion compared with other beta1 mutants.	Nitrogen	15-16	protein tyrosine kinase 2	Homo sapiens	122-143
32223162-11	2020	If 1-Gd is dissolved in THF instead of Et2O under N2, the irreversible formation of an (N2)3- complex [K(crypt)][(THF)(R2N)2Gd]2[micro-eta2:eta2-N2], 9-Gd, is observed.	Nitrogen	50-52	DNA polymerase iota	Homo sapiens	135-139
32223162-11	2020	If 1-Gd is dissolved in THF instead of Et2O under N2, the irreversible formation of an (N2)3- complex [K(crypt)][(THF)(R2N)2Gd]2[micro-eta2:eta2-N2], 9-Gd, is observed.	Nitrogen	50-52	DNA polymerase iota	Homo sapiens	140-144
32283937-2	2020	Here, through a hydrogel-embedding method, we are able to confine the growth of few-layer SnS2 nanosheets between a nitrogen- and sulfur-doped carbon nanotube (NS-CNT) and amorphous carbon.	Nitrogen	116-124	sodium voltage-gated channel alpha subunit 11	Homo sapiens	90-94
33578954-5	2021	Removal of the N-glycosylation sites on the I-like domain of integrin beta1 (termed the Delta4-6 beta1 mutant) suppressed focal adhesion kinase (FAK) signaling, cell migration, and adhesion compared with other beta1 mutants.	Nitrogen	15-16	protein tyrosine kinase 2	Homo sapiens	145-148
33578036-0	2021	Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 Spike for viral entry.	Nitrogen	0-1	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	112-117
32163593-7	2020	These promising results provide the first proof of concept of the ability of Bet:G and [Ch]Cl:LA-based DESs to be used as a greener approach for the chitin homogeneous N-deacetylation.	Nitrogen	168-169	delta/notch like EGF repeat containing	Homo sapiens	77-80
33443520-5	2021	Most strikingly, the strong blue light emission by nitrogen and sulfur co-doped carbon dots (N,S-CDs) could be encapsulated in 1 to generate a dual-emission composite, namely, N,S-CDs@Eu-MOF, which shows solvent-dependent photoluminescence: N,S-CD-related blue luminescence in water and Eu-MOF-related red emission in organic solvents.	Nitrogen	51-59	lysine acetyltransferase 8	Homo sapiens	187-190
32032660-5	2020	The investigation of additional innate immunity elements revealed that A + N (or camptothecin) stimulated the expression of NLRX1, STING (stimulator of interferon genes) and two antiviral proteins, IFIT1 and IFIT3.	Nitrogen	75-76	interferon induced protein with tetratricopeptide repeats 1	Homo sapiens	198-203
31881468-3	2020	Here we present molecular dynamics simulation studies of unfolding and folding of the protein MOG in both the absence and presence of N-glycan in order to understand the role of glycosylation in the stability and flexibility of the protein.	Nitrogen	134-135	myelin oligodendrocyte glycoprotein	Homo sapiens	94-97
31912134-7	2020	Expression of mitochondrial bifunctional NAD-dependent methylene-tetrahydrofolate dehydrogenase/methenyl-tetrahydrofolate cyclohydrolase (Mthfd2) was significantly enriched in PP and liver of P, intermediate in F liver, and much lower in liver of N and J, relative to PP.	Nitrogen	41-42	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	Rattus norvegicus	138-144
33443520-5	2021	Most strikingly, the strong blue light emission by nitrogen and sulfur co-doped carbon dots (N,S-CDs) could be encapsulated in 1 to generate a dual-emission composite, namely, N,S-CDs@Eu-MOF, which shows solvent-dependent photoluminescence: N,S-CD-related blue luminescence in water and Eu-MOF-related red emission in organic solvents.	Nitrogen	51-59	lysine acetyltransferase 8	Homo sapiens	290-293
33534698-6	2021	On the other hand, nitrogen starvation suppresses TORC1 through the combined actions of the GATOR1-Sea3 complex, the Gcn2 pathway, and the TSC complex, another conserved TORC1 inhibitor.	Nitrogen	19-27	CREB regulated transcription coactivator 1	Homo sapiens	50-55
31811679-10	2020	Importantly, results of mutant protoplast-based assays and in planta analysis using NIGT1 overexpression in the spx1 spx2 double mutant indicated that the NIGT1-SPX-PHR cascade mediates nitrogen status-responsive regulation of phosphate uptake and starvation signaling.	Nitrogen	186-194	spexin hormone	Homo sapiens	161-164
33534698-6	2021	On the other hand, nitrogen starvation suppresses TORC1 through the combined actions of the GATOR1-Sea3 complex, the Gcn2 pathway, and the TSC complex, another conserved TORC1 inhibitor.	Nitrogen	19-27	CREB regulated transcription coactivator 1	Homo sapiens	170-175
32305006-0	2020	Modification of DNA structure by reactive nitrogen species as a result of 2-methoxyestradiol-induced neuronal nitric oxide synthase uncoupling in metastatic osteosarcoma cells.	Nitrogen	42-50	nitric oxide synthase 1	Homo sapiens	101-131
33524390-3	2021	Our previous work identified a connection between N-glycosylation and Rab11, a key player in the post-Golgi transport that connects recycling endosomes and other compartments.	Nitrogen	50-51	RAB11A, member RAS oncogene family	Homo sapiens	70-75
31784829-2	2020	This study showed that the anammox process deteriorated, with N-removal efficiencies rapidly decreasing from 87.2 to 45.7% when reactors were exposed to COD shocks of 1.12, 2.24 and 3.36 g L-1 (COD/N ratio 2, 4 and 6).	Nitrogen	62-63	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	153-156
31985880-1	2020	OBJECTIVES: To comprehensively investigate the role of the N6-methyladeonsine (m6A) erasers ALKBH5 and FTO in clear cell renal carcinoma (ccRCC), other RCC subtypes and Oncocytoma with respect to prognostic value and biomarker potential.	Nitrogen	59-77	alkB homolog 5, RNA demethylase	Homo sapiens	92-98
31887584-11	2020	Low-potency toxins N-sulfocarbamoyl toxins 1/2 (C1/2) were the most dominant components of PST in phytoplankton samples from February to June in 2015, while high-potency gonyautoxin 4 (GTX4) became the dominant component from July to September.	Nitrogen	19-35	sulfotransferase family 1A member 1	Homo sapiens	91-94
32892055-3	2021	NF (kg N cap-1 yr-1) and PF (kg P cap-1 yr-1) increased from 6.7 and 1.1 to 8.3 and 1.5 during 1961-2017, respectively.	Nitrogen	0-1	cyclase associated actin cytoskeleton regulatory protein 1	Homo sapiens	9-19
32892055-3	2021	NF (kg N cap-1 yr-1) and PF (kg P cap-1 yr-1) increased from 6.7 and 1.1 to 8.3 and 1.5 during 1961-2017, respectively.	Nitrogen	0-1	cyclase associated actin cytoskeleton regulatory protein 1	Homo sapiens	34-44
33331666-2	2021	The aim of this research was to find N-methylated analogs of the aggregating amylin fragments 18-22, 23-27, and 33-37, which would not themselves be susceptible to aggregation and would inhibit the aggregation of the amyloidogenic cores of the hormone.	Nitrogen	37-38	islet amyloid polypeptide	Homo sapiens	77-83
33331666-9	2021	Research on the possibility of using N-methylated analogs of amyloidogenic amylin cores as inhibitors of hormone aggregation is ongoing, with a focus on finding the minimum concentration of N-methylated peptides capable of inhibiting the aggregation of hIAPP hot spots.	Nitrogen	37-38	islet amyloid polypeptide	Homo sapiens	75-81
33331666-9	2021	Research on the possibility of using N-methylated analogs of amyloidogenic amylin cores as inhibitors of hormone aggregation is ongoing, with a focus on finding the minimum concentration of N-methylated peptides capable of inhibiting the aggregation of hIAPP hot spots.	Nitrogen	190-191	islet amyloid polypeptide	Homo sapiens	75-81
33487631-0	2021	Targeting TRPV1-mediated autophagy attenuates nitrogen mustard-induced dermal toxicity.	Nitrogen	46-54	transient receptor potential cation channel subfamily V member 1	Homo sapiens	10-15
33074222-8	2021	Increased DVB could be associated with elevated SBV, hematocrit level, and blood urea nitrogen/creatinine ratio (p = <0.001, 0.004, and 0.002, respectively).	Nitrogen	86-94	major histocompatibility complex, class II, DQ beta 3	Homo sapiens	10-13
32049604-5	2020	Notably, increase in C/N ratio led to decrease in total ammonia nitrogen (TAN) and alkalinity concentration (Alk), hence, treatments with the lowest C/N ratio had better reactor performance in terms of suitable process parameters such as Alk, pH, ORP, and TAN.	Nitrogen	0-1	phenylalanine hydroxylase	Homo sapiens	243-245
33537046-7	2020	Genes involved in the tricarboxylic acid (TCA) cycle, nitrogen assimilation, and the urea cycle, including the drastically downregulated Arginase-1 homolog, which functions in nitrogen excretion for recycling, showed lower expression levels in EL.	Nitrogen	54-62	arginase 1	Homo sapiens	137-147
31758089-3	2020	Here, we show that treatment naive normal karyotype AML as well as samples AML LSCs predominantly express the long beta-catenin-binding isoform of LEF1 in sharp contrast to normal human hematopoietic stem cells, which lack expression of the long isoform, but express the short N-terminally truncated isoform with loss of the beta-catenin-binding site.	Nitrogen	277-278	lymphoid enhancer binding factor 1	Homo sapiens	147-151
32141499-1	2020	Fucosyltransferase 8 (FUT8) and beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) are glycosyltransferases (GTases) that catalyze alpha1,6-fucosylation and alpha2,6-sialylation, respectively, in the mammalian N-glycosylation pathway.	Nitrogen	216-217	fucosyltransferase 8	Homo sapiens	0-20
33390768-8	2021	Results: With increasing hepassocin tertiles, patients had higher prevalence of fatty live, an increased waist-to-hip ratio, and neutrophil count, monocyte count, and FIB-4 index, higher levels of uric acid, blood urine nitrogen and higher sensitivity C-reactive protein.	Nitrogen	220-228	fibrinogen like 1	Homo sapiens	25-35
33080456-6	2021	In this paper, we developed a series of statistical models to predict the Total Phosphorus (TP) and Total Nitrogen (TN) removal performance of stormwater biofilters using various numbers of design characteristics and operational conditions.	Nitrogen	106-114	C-type lectin domain family 3 member B	Homo sapiens	116-118
32141499-1	2020	Fucosyltransferase 8 (FUT8) and beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) are glycosyltransferases (GTases) that catalyze alpha1,6-fucosylation and alpha2,6-sialylation, respectively, in the mammalian N-glycosylation pathway.	Nitrogen	216-217	fucosyltransferase 8	Homo sapiens	22-26
33537046-7	2020	Genes involved in the tricarboxylic acid (TCA) cycle, nitrogen assimilation, and the urea cycle, including the drastically downregulated Arginase-1 homolog, which functions in nitrogen excretion for recycling, showed lower expression levels in EL.	Nitrogen	176-184	arginase 1	Homo sapiens	137-147
32892055-5	2021	In 2050, NF would be 9.7, 21.7, 24.1, 27.7, and 15.5 kg N cap-1 yr-1 for the BAU, S1, S2, S3, and S4 scenarios, respectively.	Nitrogen	9-10	cyclase associated actin cytoskeleton regulatory protein 1	Homo sapiens	58-68
32182323-5	2020	According to XPS, TGA and ICP techniques, the surface coverage by the ligand increases by decreasing the size of the substituents on the nitrogen atom.	Nitrogen	137-145	T-box transcription factor 1	Homo sapiens	18-21
32338281-1	2020	Tumor suppressor candidate 3 (TUSC3) is a coding gene responsible for N-glycosylation of many critical proteins.	Nitrogen	70-71	tumor suppressor candidate 3	Homo sapiens	0-28
32338281-1	2020	Tumor suppressor candidate 3 (TUSC3) is a coding gene responsible for N-glycosylation of many critical proteins.	Nitrogen	70-71	tumor suppressor candidate 3	Homo sapiens	30-35
32518941-0	2021	Identification of 22 N-glycosites on spike glycoprotein of SARS-CoV-2 and accessible surface glycopeptide motifs: Implications for vaccination and antibody therapeutics.	Nitrogen	21-22	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	37-42
33359432-4	2022	Cellular oxidative stress occurs when reactive oxygen/nitrogen species (RO/NS) exceed the cellular reductive/antioxidant capacity.	Nitrogen	54-62	serine peptidase inhibitor Kazal type 5	Homo sapiens	72-77
32273875-5	2020	Production of the corresponding recombinant FVIII mutants or light chains indicated that removal of the N-linked glycosylation site at N2118 is sufficient to abrogate in vitro the activation of FVIII-specific CD4+ T cells by human monocyte-derived dendritic cells.	Nitrogen	104-105	coagulation factor VIII	Homo sapiens	44-49
32273875-5	2020	Production of the corresponding recombinant FVIII mutants or light chains indicated that removal of the N-linked glycosylation site at N2118 is sufficient to abrogate in vitro the activation of FVIII-specific CD4+ T cells by human monocyte-derived dendritic cells.	Nitrogen	104-105	coagulation factor VIII	Homo sapiens	194-199
33490770-4	2021	Notably, we found that the BET surface area and pore volume of copper oxides measured by N2 adsorption-desorption decrease with the elevation of calcination temperature.	Nitrogen	89-91	delta/notch like EGF repeat containing	Homo sapiens	27-30
31932843-0	2020	IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution.	Nitrogen	33-34	immunoglobulin heavy variable 3-69-1 (pseudogene)	Homo sapiens	0-4
33333896-6	2020	Actinomycetes also increased nitrogen availability in soil and legume tissue and seeds, which induced the activity of key nitrogen metabolizing enzymes, e.g., glutamine synthetase, glutamate synthase, and nitrate reductase.	Nitrogen	29-37	inducible nitrate reductase [NADH] 1	Glycine max	181-222
33333896-6	2020	Actinomycetes also increased nitrogen availability in soil and legume tissue and seeds, which induced the activity of key nitrogen metabolizing enzymes, e.g., glutamine synthetase, glutamate synthase, and nitrate reductase.	Nitrogen	122-130	inducible nitrate reductase [NADH] 1	Glycine max	181-222
32992148-2	2020	In this study, a novel process, integrating the partial nitritation/anammox and hydroxyapatite crystallization (PNA-HAP) in a single airlift reactor, was developed for the simultaneous nitrogen removal and P recovery from synthetic digestion effluent.	Nitrogen	185-193	reticulon 3	Homo sapiens	116-119
32992148-8	2020	In sum, the results are evidence of the feasibility of simultaneous nitrogen removal and P recovery through one-stage PNA-HAP process for digestion effluent.	Nitrogen	68-76	reticulon 3	Homo sapiens	122-125
33263384-9	2020	Common nsp4 interactors include N-linked glycosylation machinery, unfolded protein response associated proteins, and antiviral innate immune signaling factors.	Nitrogen	32-33	ORF1a polyprotein;ORF1ab polyprotein	Severe acute respiratory syndrome coronavirus 2	7-11
32058685-2	2020	Back-gated field-effect transistor (FET) based SnS2 sensor successfully detects HCHO with concentrations down to 1 ppb in nitrogen atmosphere.	Nitrogen	122-130	sodium voltage-gated channel alpha subunit 11	Homo sapiens	47-51
32531122-8	2021	Furthermore, we show that removal of N-linked glycosyl residues from these IgG did not interfere with its entry into the podocytes but eliminated its ability to upregulate CAMK4 and cause podocyte injury.	Nitrogen	37-38	calcium/calmodulin dependent protein kinase IV	Homo sapiens	172-177
31877400-8	2020	Absolute N emissions were higher for all intensification scenarios (up to 124 kg N ha-1) compared to the baseline (80 kg N ha-1) due to increased animal numbers and higher feed and/or fertiliser inputs.	Nitrogen	9-10	solute carrier family 9 member B1	Homo sapiens	81-87
31877400-8	2020	Absolute N emissions were higher for all intensification scenarios (up to 124 kg N ha-1) compared to the baseline (80 kg N ha-1) due to increased animal numbers and higher feed and/or fertiliser inputs.	Nitrogen	9-10	solute carrier family 9 member B1	Homo sapiens	121-127
33581410-7	2021	Furthermore, we reveal mutation-specific changes in engagement with N-glycosylation components, suggesting distinct requirements for 1 Tg variant on dual engagement of both oligosaccharyltransferase complex isoforms for degradation.	Nitrogen	68-69	thyroglobulin	Homo sapiens	135-137
33218895-0	2021	Exploration of nitrogen heterocycle scaffolds for the development of potent human neutrophil elastase inhibitors.	Nitrogen	15-23	elastase, neutrophil expressed	Homo sapiens	82-101
31850996-1	2020	OBJECTIVE: To investigate the influence of intravenous (iv) fluid volumes on the secretion of N-terminal-pro-brain natriuretic peptide (NT-Pro-BNP) in colorectal surgical patients and its association with cardiopulmonary complications (CPC).	Nitrogen	94-95	natriuretic peptide B	Homo sapiens	143-146
33232205-3	2020	By using a panel of rabbit antisera against virions and five structural proteins together with a convalescent serum, the spike (S) glycoprotein was shown to be N-linked glycosylated, PNGase F-sensitive, endoglycosidase H-resistant and cleaved by Furin-like proteases into S1 and S2 subunits.	Nitrogen	160-161	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	121-126
33254634-4	2020	Here we found total nitrogen (TN) loss of China showed an overall downward trend from 2007 to 2016, as a result of abatement strategies for China on "Soil Testing and Formula Fertilization" and "Reducing Fertilizer Application while Increase the Efficiency", based on the data of National Agricultural Pollution Survey.	Nitrogen	20-28	C-type lectin domain family 3 member B	Homo sapiens	30-32
31879129-2	2020	Although the Shank N-terminal domain and ankyrin repeats domain tandem (NTD-ANK) is known to bind to Ras and Rap1, the molecular mechanism underlying and functional significance of the bindings in synapses are unknown.	Nitrogen	19-20	fuzzy planar cell polarity protein	Homo sapiens	72-75
31912347-1	2020	OBJECTIVE: The objective is to study the effect of individual N-glycosylation sequon on Suc2 activity and stability, and improve inulin conversion capacity and ethanol production of yeast by manipulating the key N-glycosylation sequon in Suc2.	Nitrogen	212-213	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	88-92
31912347-1	2020	OBJECTIVE: The objective is to study the effect of individual N-glycosylation sequon on Suc2 activity and stability, and improve inulin conversion capacity and ethanol production of yeast by manipulating the key N-glycosylation sequon in Suc2.	Nitrogen	212-213	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	238-242
31912347-2	2020	RESULTS: Based on previous reported data, it could be deduced that both the activity and thermal stability of Suc2 are probably influenced by some key N-glycosylation sequons.	Nitrogen	151-152	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	110-114
31912347-3	2020	Thus, totally 13 N-glycosylation residues of Suc2 were individually deglycosylated by site-directed mutagenesis.	Nitrogen	17-18	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	45-49
33218895-3	2021	We present here a new series of pyrazolopyridine and pyrrolopyridine derivatives as HNE inhibitors designed as modifications of our previously synthesized indazoles and indoles in order to evaluate effects of the change in position of the nitrogen and/or the insertion of an additional nitrogen in the scaffolds on biological activity and chemical stability.	Nitrogen	239-247	elastase, neutrophil expressed	Homo sapiens	84-87
31912347-4	2020	Fermentation results indicated that deglycosylation at N4, N78 and N146 sequons improved Suc2 activity and ethanol production of host strains, whereas deglycosylation at N45 showed an opposite effect.	Nitrogen	55-57	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	89-93
31912347-4	2020	Fermentation results indicated that deglycosylation at N4, N78 and N146 sequons improved Suc2 activity and ethanol production of host strains, whereas deglycosylation at N45 showed an opposite effect.	Nitrogen	55-56	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	89-93
31912347-4	2020	Fermentation results indicated that deglycosylation at N4, N78 and N146 sequons improved Suc2 activity and ethanol production of host strains, whereas deglycosylation at N45 showed an opposite effect.	Nitrogen	59-60	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	89-93
32871126-2	2020	This study aims to examine how medium nitrogen level (240 kg/hm2) affects the starch granule development, starch accumulation, and structural characteristics of wheat starch.	Nitrogen	38-46	cholinergic receptor muscarinic 2	Homo sapiens	61-64
33218895-3	2021	We present here a new series of pyrazolopyridine and pyrrolopyridine derivatives as HNE inhibitors designed as modifications of our previously synthesized indazoles and indoles in order to evaluate effects of the change in position of the nitrogen and/or the insertion of an additional nitrogen in the scaffolds on biological activity and chemical stability.	Nitrogen	286-294	elastase, neutrophil expressed	Homo sapiens	84-87
31912347-5	2020	Carbohydrate depletion of Suc2 N4 especially endowed the host strain with better ethanol fermentation performance from inulin when the strain was cultured under the higher temperature for 48 h, indicating that deglycosylation of N4 might improve the thermal stability of the Suc2.	Nitrogen	31-32	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	26-30
31912347-5	2020	Carbohydrate depletion of Suc2 N4 especially endowed the host strain with better ethanol fermentation performance from inulin when the strain was cultured under the higher temperature for 48 h, indicating that deglycosylation of N4 might improve the thermal stability of the Suc2.	Nitrogen	31-32	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	275-279
31912347-5	2020	Carbohydrate depletion of Suc2 N4 especially endowed the host strain with better ethanol fermentation performance from inulin when the strain was cultured under the higher temperature for 48 h, indicating that deglycosylation of N4 might improve the thermal stability of the Suc2.	Nitrogen	31-33	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	26-30
31912347-5	2020	Carbohydrate depletion of Suc2 N4 especially endowed the host strain with better ethanol fermentation performance from inulin when the strain was cultured under the higher temperature for 48 h, indicating that deglycosylation of N4 might improve the thermal stability of the Suc2.	Nitrogen	31-33	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	275-279
31912347-6	2020	CONCLUSIONS: Carbohydrate chains at N4, N45, N78 and N146 played an important role in modulating Suc2 activity and inulin catabolism of the S. cerevisiae strain.	Nitrogen	2-3	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	97-101
31912347-6	2020	CONCLUSIONS: Carbohydrate chains at N4, N45, N78 and N146 played an important role in modulating Suc2 activity and inulin catabolism of the S. cerevisiae strain.	Nitrogen	9-10	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	97-101
31858211-10	2020	Dietary supplementation with a high n-6/n-3 ratio downregulated the protein expression of Cx45 and Panx1 in diabetic rats (p < 0.05-p < 0.01), while Cx43 immunoexpression was increased in diabetic rats fed with high and low n-6/n-3 ratios (p < 0.01-p < 0.001).	Nitrogen	16-17	gap junction protein, gamma 1	Rattus norvegicus	90-94
31858211-10	2020	Dietary supplementation with a high n-6/n-3 ratio downregulated the protein expression of Cx45 and Panx1 in diabetic rats (p < 0.05-p < 0.01), while Cx43 immunoexpression was increased in diabetic rats fed with high and low n-6/n-3 ratios (p < 0.01-p < 0.001).	Nitrogen	22-23	gap junction protein, gamma 1	Rattus norvegicus	90-94
32711626-3	2020	The detector based on GaN p-GaN/oxide layer/n-GaN structure showed high UV response with fast speed.	Nitrogen	20-21	gigaxonin	Homo sapiens	22-25
32711626-3	2020	The detector based on GaN p-GaN/oxide layer/n-GaN structure showed high UV response with fast speed.	Nitrogen	20-21	gigaxonin	Homo sapiens	28-31
32711626-3	2020	The detector based on GaN p-GaN/oxide layer/n-GaN structure showed high UV response with fast speed.	Nitrogen	20-21	gigaxonin	Homo sapiens	28-31
32871226-8	2020	Through separating membrane and cytosolic proteins, we demonstrated that both the expression and membrane transport ratio of glucose transporter 1 (GLUT1), which is responsible for glucose transport in fetal hepatocytes, were upregulated, accompanied by increased expression of N-glycosyltransferase STT3A, which contributes to the N-glycosylation of GLUT1.	Nitrogen	332-333	solute carrier family 2 member 1	Rattus norvegicus	148-153
32867594-1	2020	Nitrate transporter 2.5 (NRT2.5) was originally characterized as the transporter for nitrogen (N) limitation.	Nitrogen	85-93	nitrate transporter2.5	Arabidopsis thaliana	0-23
31693237-5	2020	In previous cell-based assays, we found that certain N-terminally truncated PTH and PTHrP antagonist peptides function as inverse agonists and thus can reduce the high rates of basal cAMP signaling exhibited by the mutant PTHR1s of JMC in vitro.	Nitrogen	53-54	parathyroid hormone	Mus musculus	76-79
31995179-17	2021	Doxorubicin activated myocardial MMP-2 in mouse hearts and human cardiomyocytes, including de novo expression of an N-terminal truncated MMP-2 isoform which is exclusively expressed by increased oxidative stress.	Nitrogen	116-117	matrix metallopeptidase 2	Homo sapiens	137-142
31969386-5	2020	Notably, rather than inhibiting glycolysis, 2DG modified N-glycosylation, which augmented antitumor activity and cell surface retention of IL-2R of T cells.	Nitrogen	0-1	interleukin 2 receptor subunit alpha	Homo sapiens	139-144
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	phosphoinositide binding protein ATG18	Saccharomyces cerevisiae S288C	96-101
32846216-11	2020	In conclusion, SELENOV conferred protections in vivo and in vitro against the reactive oxygen and nitrogen species-mediated ER stress-related signaling and oxidative injuries.	Nitrogen	98-106	selenoprotein V	Mus musculus	15-22
31974202-7	2021	These results suggest that desialylation of O-glycans of GPIbalpha induces unfolding of the mechanosensory domain, subsequent GPIb-IX signaling including amplified desialylation of N-glycans, and eventually rapid platelet clearance.	Nitrogen	181-182	glycoprotein 1b, alpha polypeptide	Mus musculus	57-66
33176830-0	2020	Functional identification of potential non-canonical N-glycosylation sites within Cav3.2 T-type calcium channels.	Nitrogen	53-54	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	82-88
33176830-6	2020	Therefore, these newly identified asparagine residues within non-canonical motifs add to those previously reported in canonical sites and suggest that N-glycosylation of Cav3.2 may also occur at non-canonical motifs to control expression of the channel in the plasma membrane.	Nitrogen	151-152	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	170-176
33176135-0	2020	Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.	Nitrogen	41-49	AT-rich interaction domain 4B	Rattus norvegicus	28-32
31927202-4	2020	Sequence analysis revealed that the predicted barbel steed MOSPD2 protein contained an N-terminal extracellular portion composed of a CRAL-TRIO domain, a motile sperm domain, and a transmembrane domain, as well as a short C-terminal intracellular domain.	Nitrogen	87-88	motile sperm domain containing 2	Homo sapiens	59-65
31962012-7	2020	Indeed, only one variant, in the conserved N-terminal zinc finger of GATA4, was considered pathogenic, with functional analysis confirming differences in its ability to regulate Sox9 and AMH and in protein interaction with ZFPM2.	Nitrogen	43-44	SRY-box transcription factor 9	Homo sapiens	178-182
33176135-2	2020	Metabolites and genes related to BCAA metabolism and nitrogen handling were strongly associated with glycine in correlation analyses.	Nitrogen	53-61	AT-rich interaction domain 4B	Rattus norvegicus	33-37
32971315-6	2021	The most important O&NS biomarkers predicting an increased SBP were in descending order of significance: LOOH, AOPP and SOD.	Nitrogen	21-23	selenium binding protein 1	Homo sapiens	59-62
31809770-2	2020	The incretin hormones, glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) and the related hormone glucagon-like peptide-2 (GLP-2) are all rapidly N-terminally truncated with severe loss of intrinsic activity.	Nitrogen	182-183	glucagon like peptide 1 receptor	Homo sapiens	103-108
31809770-7	2020	Our overall conclusion is that the N-terminus is essential for receptor activation as GIP N-terminal truncation leads to decreased/lost intrinsic activity and antagonism (similar to GLP-1 and GLP-2), whereas the C-terminal extension of GIP(1-42), as compared to GLP-1, GLP-2 and glucagon (29-33 amino acids), has no apparent impact on the GIPR in vitro, but may play a role for other properties such as stability and tissue distribution.	Nitrogen	35-36	glucagon like peptide 1 receptor	Homo sapiens	262-267
31740367-0	2020	N-terminal fusion of the N-terminal domain of bacterial enzyme I facilitates recombinant expression and purification of the human RNA demethylases FTO and Alkbh5.	Nitrogen	0-1	alkB homolog 5, RNA demethylase	Homo sapiens	155-161
33106428-5	2020	Mutant strains tolerant to levels of aromatic acids near the solubility limit were then analyzed by whole genome sequencing, which revealed prevalent point mutations in a transcriptional activator (Aro80) that is responsible for regulating the use of aromatic amino acids as the nitrogen source.	Nitrogen	279-287	Aro80p	Saccharomyces cerevisiae S288C	198-203
33182928-1	2020	Single shot hybrid fs/ps-CARS spectroscopy of N2 is demonstrated at repetition rate up to 5 kHz using an amplified probe delivering a constant energy per pulse between 1 and 5 kHz.	Nitrogen	46-48	cysteinyl-tRNA synthetase 1	Homo sapiens	25-29
31740367-0	2020	N-terminal fusion of the N-terminal domain of bacterial enzyme I facilitates recombinant expression and purification of the human RNA demethylases FTO and Alkbh5.	Nitrogen	25-26	alkB homolog 5, RNA demethylase	Homo sapiens	155-161
31769101-9	2020	Removal of N-linked glycans and DNA by enzymatic PNGase F and DNase I treatment had positive effects on the clinical performance of Triton X-100 &amp; SDS dpPHV, whereas this treatment of trypsin &amp; Triton X-100 dpPHV induced the lowest degree of inflammation of all tested xenogeneic implants.	Nitrogen	11-12	deoxyribonuclease-1	Ovis aries	62-69
33073996-2	2021	N-glycosylation of PD-L1 affects its interaction with PD-1, but little is known about the distribution of glycoforms at its four NXS/T sequons.	Nitrogen	0-1	programmed cell death 1	Homo sapiens	54-58
31919097-0	2020	Use of the LC3B-fusion technique for biochemical and structural studies of proteins involved in the N-degron pathway.	Nitrogen	100-101	microtubule associated protein 1 light chain 3 beta	Homo sapiens	11-15
33064451-3	2020	We conducted a comprehensive mass spectrometric analysis of the N-glycosylation profiles of the SARS-CoV-2 spike proteins using signature ions-triggered electron-transfer/higher-energy collision dissociation (EThcD) mass spectrometry.	Nitrogen	64-65	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	107-112
33064451-4	2020	The patterns of N-glycosylation within the recombinant ectodomain and S1 subunit of the SARS-CoV-2 spike protein were characterized using this approach.	Nitrogen	16-17	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	99-104
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	12-20	amine oxidase copper containing 1	Homo sapiens	80-83
32043277-0	2021	The PRT6 N-degron pathway restricts VERNALIZATION 2 to endogenous hypoxic niches to modulate plant development.	Nitrogen	9-10	proteolysis 6	Arabidopsis thaliana	4-8
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	54-62	amine oxidase copper containing 1	Homo sapiens	80-83
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	54-62	amine oxidase copper containing 1	Homo sapiens	80-83
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	54-62	amine oxidase copper containing 1	Homo sapiens	80-83
32726584-6	2020	These results suggest that both Stt4p and Pik1p have important roles in the microautophagy of the vacuole in the stationary phase and under nitrogen starvation conditions.	Nitrogen	140-148	1-phosphatidylinositol 4-kinase	Saccharomyces cerevisiae S288C	42-47
33135143-3	2021	The static simulation method and related analysis techniques were used to explore the release characteristics of different forms of inorganic nitrogen and its effect on TN and Chla in overlying water from the different water layers.	Nitrogen	142-150	C-type lectin domain family 3 member B	Homo sapiens	169-171
33135143-8	2021	NO3--N in sediments was the main contributor of TN and Chla changes in the overlying water and its content can reflect the nitrogen pollution trend of the water body to a certain extent.	Nitrogen	123-131	C-type lectin domain family 3 member B	Homo sapiens	48-50
31932307-4	2020	Through in ovo electroporation in embryonic chicken spinal cords, we demonstrate that the N-terminal Tinman (TN) domain and C-terminal (CT) domain synergistically promote OL differentiation by recruiting distinct transcriptional co-repressors, including enhancer of split Groucho 3 (GRG3), histone deacetylase 1 (HDAC1), and DNA methyltransferase 3 alpha (DNMT3A).	Nitrogen	90-91	histone deacetylase 1	Gallus gallus	290-311
31932307-4	2020	Through in ovo electroporation in embryonic chicken spinal cords, we demonstrate that the N-terminal Tinman (TN) domain and C-terminal (CT) domain synergistically promote OL differentiation by recruiting distinct transcriptional co-repressors, including enhancer of split Groucho 3 (GRG3), histone deacetylase 1 (HDAC1), and DNA methyltransferase 3 alpha (DNMT3A).	Nitrogen	90-91	histone deacetylase 1	Gallus gallus	313-318
32043277-1	2021	VERNALIZATION2 (VRN2), an angiosperm-specific subunit of the polycomb repressive complex 2 (PRC2), is an oxygen (O2 ) regulated target of the PCO branch of the PRT6 N-degron pathway of ubiquitin-mediated proteolysis.	Nitrogen	3-4	proteolysis 6	Arabidopsis thaliana	160-164
33443683-1	2021	PURPOSE: IFN4N is a glycoengineered version of recombinant human interferon alpha 2 (rhIFN-alpha2) that was modified to exhibit four N-glycosylation sites.	Nitrogen	11-12	interferon alpha 2	Homo sapiens	65-83
32042062-1	2020	The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity.	Nitrogen	10-11	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	57-62
32042062-1	2020	The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity.	Nitrogen	10-11	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	164-169
31797504-9	2020	Higher levels of cathepsin D were independently associated with diabetes mellitus, renal failure and higher levels of interleukin-6 and N-terminal pro-B-type natriuretic peptide (P &lt; 0.001 for all).	Nitrogen	136-137	cathepsin D	Homo sapiens	17-28
33409271-3	2020	The receptor-binding domain (RBD) of the 2019-nCoV spike (S) protein contains disulfide bonds and N-linked glycosylations, therefore, it is typically produced by secretion.	Nitrogen	98-99	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	51-56
32650195-3	2020	We show that the synergistic effect of Fe, N, B in the mesoporous carbon structure can derive excellent ORR activity, for which the FeNB/C-800 catalyst delivers an onset potential of 0.97 V (vs. reversible hydrogen electrode, RHE), a half-wave potential of 0.81 V (vs. RHE) and a high limiting current density (5.59 mA cm-2), comparable to a commercial Pt/C.	Nitrogen	43-44	factor interacting with PAPOLA and CPSF1	Homo sapiens	226-229
32650195-3	2020	We show that the synergistic effect of Fe, N, B in the mesoporous carbon structure can derive excellent ORR activity, for which the FeNB/C-800 catalyst delivers an onset potential of 0.97 V (vs. reversible hydrogen electrode, RHE), a half-wave potential of 0.81 V (vs. RHE) and a high limiting current density (5.59 mA cm-2), comparable to a commercial Pt/C.	Nitrogen	43-44	factor interacting with PAPOLA and CPSF1	Homo sapiens	269-272
31895557-3	2020	In Saccharomyces cerevisiae and other Saccharomyces yeasts, the gluconeogenic enzymes Fbp1, Icl1, and Mdh2 bear Nt-Pro and are conditionally destroyed by the Pro/N-degron pathway.	Nitrogen	112-113	fructose 1,6-bisphosphate 1-phosphatase	Saccharomyces cerevisiae S288C	86-90
31895557-3	2020	In Saccharomyces cerevisiae and other Saccharomyces yeasts, the gluconeogenic enzymes Fbp1, Icl1, and Mdh2 bear Nt-Pro and are conditionally destroyed by the Pro/N-degron pathway.	Nitrogen	112-113	isocitrate lyase 1	Saccharomyces cerevisiae S288C	92-96
31895557-6	2020	One question to be addressed was whether the presence of non-Pro Nt residues in K. lactis Fbp1, Icl1, and Mdh2 was accompanied, on evolutionary time scales (S. cerevisiae and K. lactis diverged ~150 million years ago), by a changed specificity of the Gid4 N-recognin.	Nitrogen	65-66	fructose 1,6-bisphosphate 1-phosphatase	Saccharomyces cerevisiae S288C	90-94
31895557-6	2020	One question to be addressed was whether the presence of non-Pro Nt residues in K. lactis Fbp1, Icl1, and Mdh2 was accompanied, on evolutionary time scales (S. cerevisiae and K. lactis diverged ~150 million years ago), by a changed specificity of the Gid4 N-recognin.	Nitrogen	65-66	isocitrate lyase 1	Saccharomyces cerevisiae S288C	96-100
31960845-3	2020	The two as-prepared catalysts N-CNTs@NiS2/Fe7S8 (overpotential of 330 mV to achieve 50 mA cm-2 and Tafel slope of 51.49 mV dec-1) and N-CNTs@NiSe2/Fe3Se4 (360 mV and 72.32 mV dec-1, respectively) exhibited considerably high OER activity in 1.0 M KOH solutions.	Nitrogen	30-31	deleted in esophageal cancer 1	Homo sapiens	123-128
31960845-3	2020	The two as-prepared catalysts N-CNTs@NiS2/Fe7S8 (overpotential of 330 mV to achieve 50 mA cm-2 and Tafel slope of 51.49 mV dec-1) and N-CNTs@NiSe2/Fe3Se4 (360 mV and 72.32 mV dec-1, respectively) exhibited considerably high OER activity in 1.0 M KOH solutions.	Nitrogen	30-31	deleted in esophageal cancer 1	Homo sapiens	175-180
31858729-7	2020	The decrease in MMP-2 post-HT correlated with improved mean pulmonary artery pressure (rs = 0.58; P = 0.0025), mean right atrial pressure (rs = 0.56; P = 0.0046), pulmonary artery wedge pressure (rs = 0.48; P = 0.016), and N-terminal pro brain natriuretic peptide (rs = 0.56; P = 0.0029).	Nitrogen	223-224	matrix metallopeptidase 2	Homo sapiens	16-21
33126484-1	2020	N-alpha-acetyltransferase 10 (NAA10) is an acetyltransferase that acetylates both N-terminal amino acid and internal lysine residues of proteins.	Nitrogen	0-1	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	30-35
32989163-4	2020	In contrast to FTO, which follows a traditional oxidative N-demethylation pathway to catalyze conversion of m6A to hm6A with subsequent slow release of A and FA, we find that ALKBH5 catalyzes a direct m6A-to-A transformation with rapid FA release.	Nitrogen	58-59	alkB homolog 5, RNA demethylase	Homo sapiens	175-181
31841694-4	2020	Sequence analysis indicated that Lc-TRAF3 is conserved in vertebrates, constituted with a N-terminal RING finger, two TRAF-type zinc fingers, and a C-terminal TRAF-MATH domain.	Nitrogen	90-91	TNF receptor-associated factor 3	Larimichthys crocea	36-41
33409271-3	2020	The receptor-binding domain (RBD) of the 2019-nCoV spike (S) protein contains disulfide bonds and N-linked glycosylations, therefore, it is typically produced by secretion.	Nitrogen	98-99	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	58-59
32445493-5	2020	Screening the collection of 374 N-glycomimetics against the plant lectin WFA and the 2 human immune lectins MGL ECD and Langerin ECD produced a number of high affinity binders as lead structures for more selective lectin targeting probes.	Nitrogen	32-33	CD207 molecule	Homo sapiens	120-128
32623356-5	2020	In cells, HMGB1 is N-glycosylated at three asparagine residues located in boxes A and B, and these N-glycans are essential for the nucleocytoplasmic transport of the protein.	Nitrogen	19-20	high mobility group box 1	Homo sapiens	10-15
31846774-2	2020	In the present study, two IRAK family members, OnIRAK1 and OnIRAK4, were identified in the Nile tilapia Oreochromis niloticus with a conserved N-terminal death domain and a protein kinase domain, similar to those of other fishes and mammals.	Nitrogen	91-92	interleukin-1 receptor-associated kinase 1	Oreochromis niloticus	47-54
32623356-7	2020	Here we have investigated the effect of the N-glycosylation of HMGB1 on its interaction with GLR using molecular modelling, after incorporation of three N-glycans on a Human HMGB1 structure (PDB code 2YRQ).	Nitrogen	44-45	high mobility group box 1	Homo sapiens	63-68
32977945-0	2020	Identification of N-glycosylation sites on AtERO1 and AtERO2 using a transient expression system.	Nitrogen	18-19	endoplasmic reticulum oxidoreductins 2	Arabidopsis thaliana	54-60
32623356-14	2020	For the first time, it is shown (at least in silico) that N-glycosylation, one of the many post-translational modifications of HMGB1, can affect drug binding.	Nitrogen	58-59	high mobility group box 1	Homo sapiens	127-132
33004847-5	2020	After irradiation, the GaN was annealed in a nitrogen environment at 950  C for 30 min.	Nitrogen	45-53	gigaxonin	Homo sapiens	23-26
31907982-4	2020	In C. elegans, we showed that the predicted promoter of Hc-akt-1 drives substantial expression in ASJ neurons of the N2 (wild-type) strain.	Nitrogen	117-119	Serine/threonine-protein kinase akt-1	Caenorhabditis elegans	59-64
31924668-12	2020	In podocytes, the N-fragment localizes to the plasma membrane, binds mDIA1, and promotes cell spreading in a cleavage-dependent way.	Nitrogen	18-19	diaphanous related formin 1	Mus musculus	69-74
32977945-5	2020	However, the exact N-glycosylation sites on AtERO1 and AtERO2 remains to be determined.	Nitrogen	19-20	endoplasmic reticulum oxidoreductins 2	Arabidopsis thaliana	55-61
33345499-0	2020	[Effect of nitrogen additions on soil pH, phosphorus contents and phosphatase activities in grassland].	Nitrogen	11-19	phenylalanine hydroxylase	Homo sapiens	38-40
33345499-5	2020	The results showed that nitrogen addition significantly reduced soil pH, TP and AlP activity, while significantly increased AcP activity, but had no significant effect on AP.	Nitrogen	24-32	phenylalanine hydroxylase	Homo sapiens	69-71
32977945-6	2020	In this work, using a plant transient expression system, we identified the N-glycosylation sites on both AtERO1 and AtERO2.	Nitrogen	75-76	endoplasmic reticulum oxidoreductins 2	Arabidopsis thaliana	116-122
33345499-6	2020	Soil pH and AlP activity significantly decreased under nitrogen addition >5 g m-2 a-1, and AcP activity significantly increased under high nitrogen addition (>10 g m-2 a-1).	Nitrogen	55-63	phenylalanine hydroxylase	Homo sapiens	5-7
31761201-5	2020	Crystal violet assay and live and dead fluorescence staining of E. coli and S. aureus showed that all the N and S coated surfaces generated, including ppHA, ppT and ppT-air, produced similarly potent, growth reduction of both bacteria by approximately 65% at 72 h compared to untreated glass control.	Nitrogen	106-107	meprin A subunit alpha	Homo sapiens	151-155
33179677-7	2020	The interaction of BIIICl(SubPc2-) with three equivalents of CN- is accompanied by the addition of two CN- to carbon atoms of SubPc2- closest to meso-nitrogen atoms forming {BIII(CN)[SubPc(CN)2]4-}2-.	Nitrogen	150-158	calcium voltage-gated channel subunit alpha1 B	Homo sapiens	19-23
31707632-3	2020	Lines of evidence indicate that the N-terminal domain, which includes the N-terminal, positively charged polybasic region and the octapeptide repeat (OR) region, is important for PrPC to convert into PrPSc after infection with prions.	Nitrogen	36-37	prion protein	Mus musculus	179-183
31707632-3	2020	Lines of evidence indicate that the N-terminal domain, which includes the N-terminal, positively charged polybasic region and the octapeptide repeat (OR) region, is important for PrPC to convert into PrPSc after infection with prions.	Nitrogen	74-75	prion protein	Mus musculus	179-183
32932820-8	2020	In P. vulgaris, we confirmed that N-starvation stimulated nodulation by regulating expression of PvNLP2, closely related to AtNLP6 and AtNLP7 with another common origin (OG0004041).	Nitrogen	34-35	Plant regulator RWP-RK family protein	Arabidopsis thaliana	124-130
32871226-8	2020	Through separating membrane and cytosolic proteins, we demonstrated that both the expression and membrane transport ratio of glucose transporter 1 (GLUT1), which is responsible for glucose transport in fetal hepatocytes, were upregulated, accompanied by increased expression of N-glycosyltransferase STT3A, which contributes to the N-glycosylation of GLUT1.	Nitrogen	278-279	solute carrier family 2 member 1	Rattus norvegicus	125-146
33124283-8	2020	The TN/TP of lakes and reservoirs had a significant correlation with the lake depth in both spring and summer, indicating that lake depth is a key factor affecting the ratio of nitrogen and phosphorus.	Nitrogen	177-185	C-type lectin domain family 3 member B	Homo sapiens	4-9
32402213-0	2020	N-Glycosylation Regulates Chitinase 3-like-1 and IL-13 Ligand Binding to IL-13 Receptor alpha2.	Nitrogen	0-1	chitinase 3 like 1	Homo sapiens	26-44
32402213-4	2020	Here, we demonstrate that IL-13Ralpha2 N-glycosylation is a critical determinant of which ligand binds.	Nitrogen	39-40	interleukin 13 receptor subunit alpha 2	Homo sapiens	26-38
32402213-5	2020	Structure-function evaluations demonstrated that Chi3l1-IL-13Ralpha2 binding was increased when sites of N-glycosylation are mutated, and studies with tunicamycin and Peptide:N-glycosidase F (PNGase F) demonstrated that Chi3l1-IL-13Ralpha2 binding and signaling were increased when N-glycosylation was diminished.	Nitrogen	105-106	chitinase 3 like 1	Homo sapiens	49-55
32402213-5	2020	Structure-function evaluations demonstrated that Chi3l1-IL-13Ralpha2 binding was increased when sites of N-glycosylation are mutated, and studies with tunicamycin and Peptide:N-glycosidase F (PNGase F) demonstrated that Chi3l1-IL-13Ralpha2 binding and signaling were increased when N-glycosylation was diminished.	Nitrogen	105-106	interleukin 13 receptor subunit alpha 2	Homo sapiens	56-68
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	135-136	interleukin 13 receptor subunit alpha 2	Homo sapiens	79-91
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	135-136	interleukin 13 receptor subunit alpha 2	Homo sapiens	154-166
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	135-136	interleukin 13 receptor subunit alpha 2	Homo sapiens	154-166
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	135-136	interleukin 13 receptor subunit alpha 2	Homo sapiens	154-166
32402213-6	2020	In contrast, structure-function experiments demonstrated that IL-13 binding to IL-13Ralpha2 was dependent on each of the four sites of N-glycosylation in IL-13Ralpha2, and experiments with tunicamycin and PNGase F demonstrated that IL-13-IL-13Ralpha2 binding was decreased when IL-13Ralpha2 N-glycosylation was diminished.	Nitrogen	206-207	interleukin 13 receptor subunit alpha 2	Homo sapiens	79-91
30902024-14	2020	These findings demonstrate that the relative CYP3A4, CYP2B6, and CYP2C19 involvement in meperidine N-demethylation depends on the enzyme activities in individual human liver microsomal samples.	Nitrogen	99-100	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	53-59
32019200-4	2020	The results show that the loss of total nitrogen (TN) and total phosphorus (TP) is concentrated in the rainy season, and the loss of TN and TP is mainly distributed in the middle and lower reaches of the main stream of the Guishui River.	Nitrogen	40-48	C-type lectin domain family 3 member B	Homo sapiens	50-52
32013195-1	2020	Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal acetyltransferase (NAT) that catalyzes the acetylation of N-termini of newly synthesized peptides.	Nitrogen	41-42	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	0-18
32013195-1	2020	Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal acetyltransferase (NAT) that catalyzes the acetylation of N-termini of newly synthesized peptides.	Nitrogen	41-42	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	20-24
32013195-1	2020	Arrest defective 1 (ARD1), also known as N(alpha)-acetyltransferase 10 (NAA10) was originally identified as an N-terminal acetyltransferase (NAT) that catalyzes the acetylation of N-termini of newly synthesized peptides.	Nitrogen	41-42	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	72-77
31993836-2	2020	Here, we propose a facile and effective strategy to design a mesopore-structured Fe/N/C catalyst for the ORR with ultrahigh BET surface area and outstanding conductivity via nanochannels of molecular sieve-confined pyrolysis of Fe2+ ions coordinated with 2,4,6-tri(2-pyridyl)-1,3,5-triazine complexes as a novel precursor with the stable coordination effect.	Nitrogen	84-85	delta/notch like EGF repeat containing	Homo sapiens	124-127
32871226-8	2020	Through separating membrane and cytosolic proteins, we demonstrated that both the expression and membrane transport ratio of glucose transporter 1 (GLUT1), which is responsible for glucose transport in fetal hepatocytes, were upregulated, accompanied by increased expression of N-glycosyltransferase STT3A, which contributes to the N-glycosylation of GLUT1.	Nitrogen	278-279	solute carrier family 2 member 1	Rattus norvegicus	148-153
32544330-0	2020	Structure and Dynamics of N-Glycosylated Human Ribonuclease 1.	Nitrogen	26-27	ribonuclease A family member 1, pancreatic	Homo sapiens	47-61
32544330-2	2020	Ribonucle-ase 1 (RNase 1), which is the human homolog of the archetypal enzyme RNase A, undergoes N-linked glycosylation at as-paragine residues 34, 76, and 88.	Nitrogen	18-19	ribonuclease A family member 1, pancreatic	Homo sapiens	79-86
31756109-0	2020	Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators.	Nitrogen	29-37	cannabinoid receptor 1 (brain)	Mus musculus	131-153
32871226-8	2020	Through separating membrane and cytosolic proteins, we demonstrated that both the expression and membrane transport ratio of glucose transporter 1 (GLUT1), which is responsible for glucose transport in fetal hepatocytes, were upregulated, accompanied by increased expression of N-glycosyltransferase STT3A, which contributes to the N-glycosylation of GLUT1.	Nitrogen	332-333	solute carrier family 2 member 1	Rattus norvegicus	125-146
33004613-5	2020	Although the majority of CHT7 and MAT3/RB proteins were observed in separate complexes by blue native-PAGE (BN-PAGE), the two proteins coimmunoprecipitated both during synchronized growth and following N deprivation, suggesting the presence of low abundance sub-complexes containing CHT7 and MAT3/RB.	Nitrogen	109-110	uncharacterized protein	Chlamydomonas reinhardtii	34-38
32039147-9	2019	Using our synthetic 15N-labeled diUbs, we establish here how a C-terminally extended UBA domain of UBXN1 confers specificity to K6 diUb while the non-extended version of the domain does not show any linkage preference.	Nitrogen	20-23	UBX domain protein 1	Homo sapiens	99-104
31973069-3	2020	Here, we examined the interaction of neuronal calcium sensor-1 (NCS-1) with natural membranes of different lipid composition as well as individual phospholipids in form of multilamellar liposomes or immobilized monolayers and characterized the role of myristoyl group and N-terminal lysine residues in membrane binding and phospholipid preference of the protein.	Nitrogen	64-65	neuronal calcium sensor 1	Homo sapiens	37-62
31913260-5	2020	In addition, we found that SGK196 N-glycosylation performs the regulatory function through the PI3K/AKT/GSK3beta signaling pathway.	Nitrogen	34-35	glycogen synthase kinase 3 beta	Homo sapiens	104-112
32417581-4	2020	Meta-regression analyses, however, indicated a shift from a positive to a negative effect on soil CH4 uptake with increasing N additions both in boreal forests (threshold = 48 kg N ha-1 yr-1) and temperate forests (threshold = 27 kg N ha-1 yr-1), while no such shift was found in subtropical and tropical forests.	Nitrogen	125-126	solute carrier family 9 member B1	Homo sapiens	179-190
32417581-4	2020	Meta-regression analyses, however, indicated a shift from a positive to a negative effect on soil CH4 uptake with increasing N additions both in boreal forests (threshold = 48 kg N ha-1 yr-1) and temperate forests (threshold = 27 kg N ha-1 yr-1), while no such shift was found in subtropical and tropical forests.	Nitrogen	125-126	solute carrier family 9 member B1	Homo sapiens	233-244
33202661-9	2020	In contrast, the inhibition of mTOR by shifting cells from oleate-medium, which lacks glucose, to pexophagy-medium, which contains glucose and is limited in nitrogen, required Ras2-activity for efficient pexophagy, strongly suggesting that the role of Ras2 in glucose sensing-associated signaling is more important in this context than its co-function in mTOR-related autophagy-inhibition.	Nitrogen	157-165	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	176-180
32922663-0	2020	Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1.	Nitrogen	120-121	maltase-glucoamylase	Homo sapiens	153-157
32922663-9	2020	Further, we identified distinct N-glycosylation pattern of CD44, MGAM, and GINM1 between NMIBC and MIBC patients, which may be associated with disease progression in bladder cancer.	Nitrogen	32-33	maltase-glucoamylase	Homo sapiens	65-69
31630795-4	2020	Bioinformatics analysis showed that VWA8 has a 34 amino acid N-terminal Matrix-Targeting Signal (MTS) that is similar to those in proteins known to localize to the mitochondrial matrix.	Nitrogen	61-62	von Willebrand factor A domain containing 8	Rattus norvegicus	36-40
33155359-7	2021	The higher nitrogen removal of the HAOBR at the reflux ratio of 300% is attributed to the presence of the anammox in the 1st anoxic compartment, which is mainly due to the lower COD concentration in the compartment at the higher reflux ratio.	Nitrogen	11-19	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	178-181
31654721-2	2020	Previous studies have reported that PML-RARalpha is cleaved by neutrophil elastase (NE), an early myeloid-specific serine protease, leading to translocation of the nuclear localization signal (NLS) of the PML protein to the N-terminal of RARalpha.	Nitrogen	84-85	elastase, neutrophil expressed	Homo sapiens	63-82
32824566-5	2020	Using this new platform, we designed primers for several functional genes in the nitrogen cycle, including napA and amoA.	Nitrogen	81-89	NSF attachment protein alpha	Homo sapiens	107-111
32849657-5	2020	Knockout of the N-glycosylation gene N-acetylglucosaminyltransferase V (MGAT5) in HEK293 cells induced altered metabolism and continuous high MICA surface expression.	Nitrogen	16-17	MHC class I polypeptide-related sequence A	Homo sapiens	142-146
33048522-1	2020	The mitochondrial outer membrane protein, mitoNEET (mNT), is an iron-sulfur protein containing an Fe2S2(His)1(Cys)3 cluster with a unique single Fe-N bond.	Nitrogen	46-47	max binding protein	Mus musculus	52-55
32785052-7	2020	The main reason for this phenomenon was revealed to be due to apparent electronic repulsion between the replaced nitrogen atom (N1) of piperazine in 3b and the Ndelta atom of His191 in NAMPT by our in silico binding mode analyses.	Nitrogen	113-121	nicotinamide phosphoribosyltransferase	Homo sapiens	185-190
31514005-6	2020	Furthermore, the results show that Feammox may transform nitrogen at a rate of approximately 2.4-22.5 kg N ha-1 yr-1 within the investigated area.	Nitrogen	57-65	solute carrier family 9 member B1	Homo sapiens	105-116
33048522-3	2020	To further understand the effect of this unique Fe-N bond on the metal cluster and protein, we used atomic force microscopy-based single-molecule force spectroscopy (AFM-SMFS) to investigate the mechanical unfolding mechanism of an mNT monomer, focusing on the rupture pathway and kinetic stability of the cluster.	Nitrogen	51-52	max binding protein	Mus musculus	232-235
33048522-5	2020	Moreover, this Fe-N bond enabled a dynamic and labile iron-sulfur cluster, as multiple unfolding pathways of mNT with a unique Fe2S2(Cys)3 intermediate were observed accordingly.	Nitrogen	18-19	max binding protein	Mus musculus	109-112
32996649-12	2020	Furthermore, increased N-glycosylation of CREBH, as achieved by overexpressing GnT-V could significantly improve liver lesion caused by unglycosylation of CREBH.	Nitrogen	23-24	mannoside acetylglucosaminyltransferase 5	Mus musculus	79-84
31769197-4	2020	GATA1 translation results in the production of the full-length protein and of a shorter variant (GATA1s) lacking the N-terminal transactivation domain, which is functionally deficient in supporting erythropoiesis.	Nitrogen	117-118	GATA binding protein 1	Mus musculus	97-102
32644795-2	2020	In the present study, by coating ~ 3 nm MoSx on nitrogen-doped graphene (NG) pre-engrafted on a flexible carbon cloth (MNG) as a model system, an extremely low Tafel slope of 39.6 mV dec-1 with cyclic stability up to 5000 cycles is obtained.	Nitrogen	48-56	deleted in esophageal cancer 1	Homo sapiens	183-188
32338107-10	2020	Bioinformatics prediction and western blotting methods validated the targets of miR-181a in vitro.Results: Curcumin treatment alleviated cisplatin-induced nephrotoxicity as validated by the blood urea nitrogen (BUN) values, and histological analysis of kidneys.	Nitrogen	201-209	microRNA 181a-2	Mus musculus	80-88
32793266-8	2020	Even though, highest N uptake was observed in the treatment with continuous supply of N with 200 kg N ha-1 in five splits it did not influence the N efficiencies parameters which indicate that yield of canola and mustard are limited by N rate in these environments.	Nitrogen	21-22	solute carrier family 9 member B1	Homo sapiens	100-106
32793266-8	2020	Even though, highest N uptake was observed in the treatment with continuous supply of N with 200 kg N ha-1 in five splits it did not influence the N efficiencies parameters which indicate that yield of canola and mustard are limited by N rate in these environments.	Nitrogen	86-87	solute carrier family 9 member B1	Homo sapiens	100-106
32793266-8	2020	Even though, highest N uptake was observed in the treatment with continuous supply of N with 200 kg N ha-1 in five splits it did not influence the N efficiencies parameters which indicate that yield of canola and mustard are limited by N rate in these environments.	Nitrogen	86-87	solute carrier family 9 member B1	Homo sapiens	100-106
31927554-12	2020	Treatment with EVs overexpressing Oct-4 significantly decreased serum Crea and blood urea nitrogen levels and rescued kidney fibrosis, as indicated by the low proportion of Masson staining, high number of PCNA-positive cells, and low number of TUNEL-positive cells.	Nitrogen	90-98	POU domain, class 5, transcription factor 1, related sequence 1	Mus musculus	34-39
31773574-5	2020	Here we describe a fast, high-throughput FP assay to quantify the binding of fluorescently labeled inositol 1,4,5-trisphosphate (IP3) to N-terminal fragments of the IP3 receptor.	Nitrogen	137-138	inositol 1,4,5-trisphosphate receptor type 3	Homo sapiens	165-177
30734162-1	2020	Being able to measure total nitrogen (TN) is important for following the nitrogen budget.	Nitrogen	28-36	C-type lectin domain family 3 member B	Homo sapiens	38-40
30734162-1	2020	Being able to measure total nitrogen (TN) is important for following the nitrogen budget.	Nitrogen	73-81	C-type lectin domain family 3 member B	Homo sapiens	38-40
32793266-8	2020	Even though, highest N uptake was observed in the treatment with continuous supply of N with 200 kg N ha-1 in five splits it did not influence the N efficiencies parameters which indicate that yield of canola and mustard are limited by N rate in these environments.	Nitrogen	86-87	solute carrier family 9 member B1	Homo sapiens	100-106
32709014-11	2020	Therefore, increasing evidence suggests that N-glycosylation of GPR176 and its downstream G-protein signal regulation may be involved in pathways characterizing human chronotypes.	Nitrogen	45-46	G protein-coupled receptor 176	Homo sapiens	64-70
33079488-4	2020	SnS2 nanoparticle is encapsulated in nitrogen-doped hollow carbon nanobox (SnS2 @C).	Nitrogen	37-45	sodium voltage-gated channel alpha subunit 11	Homo sapiens	0-4
32482891-5	2020	We show here that the secreted form of ACLP contains N-linked glycosylation and that inhibition of glycosylation results in its intracellular retention.	Nitrogen	53-54	AE binding protein 1	Homo sapiens	39-43
32482891-11	2020	Our findings highlight the importance of N-linked glycosylation of ACLP for its secretion and contribute to our understanding of ACLP-dependent disease pathologies.	Nitrogen	41-42	AE binding protein 1	Homo sapiens	67-71
31906170-5	2019	ORR results from N-PC show the four-electron pathway (average n = 3.6) for ORRs with a Tafel slope of 86 mV dec-1 and a half-wave potential of 0.76 V. For OERs and HERs, N-PC@Ni shows better overpotential values of 314 and 179 mV at 10 mA cm-2, and its corresponding Tafel slopes are 132 and 98 mV dec-1, respectively.	Nitrogen	17-18	deleted in esophageal cancer 1	Homo sapiens	108-113
31906170-5	2019	ORR results from N-PC show the four-electron pathway (average n = 3.6) for ORRs with a Tafel slope of 86 mV dec-1 and a half-wave potential of 0.76 V. For OERs and HERs, N-PC@Ni shows better overpotential values of 314 and 179 mV at 10 mA cm-2, and its corresponding Tafel slopes are 132 and 98 mV dec-1, respectively.	Nitrogen	17-18	deleted in esophageal cancer 1	Homo sapiens	298-303
31906170-5	2019	ORR results from N-PC show the four-electron pathway (average n = 3.6) for ORRs with a Tafel slope of 86 mV dec-1 and a half-wave potential of 0.76 V. For OERs and HERs, N-PC@Ni shows better overpotential values of 314 and 179 mV at 10 mA cm-2, and its corresponding Tafel slopes are 132 and 98 mV dec-1, respectively.	Nitrogen	170-171	deleted in esophageal cancer 1	Homo sapiens	108-113
31906170-5	2019	ORR results from N-PC show the four-electron pathway (average n = 3.6) for ORRs with a Tafel slope of 86 mV dec-1 and a half-wave potential of 0.76 V. For OERs and HERs, N-PC@Ni shows better overpotential values of 314 and 179 mV at 10 mA cm-2, and its corresponding Tafel slopes are 132 and 98 mV dec-1, respectively.	Nitrogen	170-171	deleted in esophageal cancer 1	Homo sapiens	298-303
33079488-4	2020	SnS2 nanoparticle is encapsulated in nitrogen-doped hollow carbon nanobox (SnS2 @C).	Nitrogen	37-45	sodium voltage-gated channel alpha subunit 11	Homo sapiens	75-79
31734159-5	2019	Transcriptomic analyses revealed that isobutanol induces a nitrogen starvation response via GLN3 and GCN4, upregulating amino acid biosynthesis and nitrogen scavenging while downregulating glycolysis, cell wall biogenesis, and membrane lipid biosynthesis.	Nitrogen	59-67	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	101-105
32975939-6	2020	The Ag+(C2H2)n (n = 1-4) species are shown to be eta2-bonded, cation-pi complexes with red-shifted C-H stretches on the acetylene ligands.	Nitrogen	13-14	DNA polymerase iota	Homo sapiens	49-53
31734159-5	2019	Transcriptomic analyses revealed that isobutanol induces a nitrogen starvation response via GLN3 and GCN4, upregulating amino acid biosynthesis and nitrogen scavenging while downregulating glycolysis, cell wall biogenesis, and membrane lipid biosynthesis.	Nitrogen	148-156	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	101-105
31714482-9	2019	In addition, N15 treatment markedly increased the newly mature neurons and enhanced the expression levels of growth-associated protein-43, synaptophysin, brain-derived neurotrophic factor and neurotrophin-3 in the hippocampus.	Nitrogen	13-16	growth associated protein 43	Rattus norvegicus	109-137
32371117-7	2020	Furthermore, N1 nitrogen of the quinoline scaffold formed an essential hydrogen bond with the hinge region key amino acids Ala213 and Ala173 in AURKA and AURKB, respectively.	Nitrogen	16-24	aurora kinase A	Homo sapiens	144-149
32806348-3	2020	N flux of wet deposition in the hinterland of the TGR area were 13.56 +- 2.95 kg N ha-1 yr-1, of which the proportions of NO3--N, NH4+-N and DON were 60.9%, 25.1% and 14.0%, respectively.	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	81-92
32458917-2	2020	A recent report of O2-dependent aliphatic C-C bond cleavage at ambient temperature in Ni(ii) diketonate complexes supported by a tridentate nitrogen donor ligand [(MBBP)Ni(PhC(O)CHC(O)Ph)]Cl (7-Cl; MBBP = 2,6-bis(1-methylbenzimidazol-2-yl)pyridine) in the presence of NEt3 spurred our interest in further examining the chemistry of such complexes.	Nitrogen	140-148	tetraspanin 2	Homo sapiens	268-272
32608808-9	2020	There were 23 KO pathways involved in nitrogen metabolism in archaea, involving nifH, nifK, and nifD nitrogenase genes in nitrogen fixation.	Nitrogen	38-46	nucleolar protein interacting with the FHA domain of MKI67	Homo sapiens	86-90
31929866-9	2019	The serum levels and relative expressions of SDF-1 and CXCR4 were positively correlated with blood urea nitrogen, parathyroid hormone, and high-sensitivity C-reactive protein and inversely correlated with hemoglobin.	Nitrogen	104-112	C-X-C motif chemokine ligand 12	Homo sapiens	45-50
32517158-7	2020	Mutation of the two N-glycosylation sites on  21-121 EMCN abolished its interaction with VEGFR2 and its function in VEGFR2 internalization.	Nitrogen	20-21	kinase insert domain protein receptor	Mus musculus	89-95
32806348-10	2020	N flux of wet deposition in the entire TGR area ranged from 12.17 to 51.93 kg N ha-1 yr-1, with an average of 26.81 kg N ha-1 yr-1.	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	78-89
32517158-7	2020	Mutation of the two N-glycosylation sites on  21-121 EMCN abolished its interaction with VEGFR2 and its function in VEGFR2 internalization.	Nitrogen	20-21	kinase insert domain protein receptor	Mus musculus	116-122
32517158-8	2020	These results reveal  21-121 EMCN as the minimal extracellular domain sufficient for VEGFR2-mediated endothelial function and demonstrate an important role for N-glycosylation in VEGFR2 interaction, internalization, and angiogenic activity.	Nitrogen	32-33	kinase insert domain protein receptor	Mus musculus	85-91
31710471-6	2019	Cells lacking Cap2p showed altered localization of Msb2p and increased shedding of Msb2p"s N-terminal glycosylated domain.	Nitrogen	91-92	F-actin-capping protein subunit beta	Saccharomyces cerevisiae S288C	14-19
32806348-10	2020	N flux of wet deposition in the entire TGR area ranged from 12.17 to 51.93 kg N ha-1 yr-1, with an average of 26.81 kg N ha-1 yr-1.	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	119-130
31196770-7	2019	Patients with a UTI had lower renal function (higher blood urea nitrogen [P = 0.001], higher creatinine [P = 0.001]), lower systolic blood pressure (P = 0.04), higher A-DROP scores (P = 0.005) and higher positive blood culture rates (P = 0.03) than those without a UTI.	Nitrogen	64-72	alpha-1-microglobulin/bikunin precursor	Homo sapiens	16-19
31548687-4	2019	We found that the modulating effect is primarily restricted to the less abundant beta-isoform (hbetaAT) of hAT that lacks N-glycosylation at position 135.	Nitrogen	122-123	transmembrane serine protease 11D	Homo sapiens	107-110
31548687-4	2019	We found that the modulating effect is primarily restricted to the less abundant beta-isoform (hbetaAT) of hAT that lacks N-glycosylation at position 135.	Nitrogen	122-123	transmembrane serine protease 11D	Homo sapiens	11-13
32045805-3	2020	To solve this problem, we introduce a simple and efficient way to prepare a photocatalyst, ZnIn2S4 grown on nitrogen-doped hollow carbon spheres (ZIS-NHC), which is an effective catalyst that can used to reduce aqueous Cr(VI).	Nitrogen	108-116	zinc finger RANBP2-type containing 2	Homo sapiens	146-149
32387808-5	2020	Complement and coagulation cascade, nitrogen metabolism, negative regulation of peptidase activity, and response to ROS were among the biological processes and pathways perturbed by the ETX exposure.	Nitrogen	36-44	pCP8533etx_p28	Clostridium perfringens	186-189
31615845-0	2020	How to use N-terminal pro-brain natriuretic peptide (NT-proBNP) in assessing disease severity in bronchiolitis.	Nitrogen	11-12	natriuretic peptide B	Homo sapiens	26-51
31112603-6	2020	We provide in silico, molecular dynamics and experimental data to support that CucWi-N (i) possesses high capability to target mortalin-p53 interaction and hnRNP-K proteins, (ii) triggers replicative senescence and inhibits metastatic potential of the cancer cells, and (iii) inhibits tumor progression and metastasis in vivo.	Nitrogen	85-86	heterogeneous nuclear ribonucleoprotein K	Homo sapiens	156-163
31682105-4	2019	In dark conditions, the N, Fe-doped CoS2 on self-supported stainless steel (SS) mesh shows a small OER overpotential (215 mV) at a current density of 10 mA cm-2, a reduced Tafel slope (43.2 mV dec-1), and negligible activity decay after 10 000 cycles.	Nitrogen	24-25	deleted in esophageal cancer 1	Homo sapiens	193-198
31615845-2	2020	Brain natriuretic peptide (BNP) and the inactive portion of its pro-hormone: N-terminal pro-BNP (NT-proBNP) are excreted in response to cardiomyocyte stretching and are established biomarkers in cardiac failure.	Nitrogen	28-29	natriuretic peptide B	Homo sapiens	0-25
32045605-6	2020	C-terminal part of the amino sequence of Slp2 protein was found to be highly similar to that of the conserved C-terminal region of SlpA protein of L. crispatus Zj001 isolated from pig intestines and CbsA protein of L. crispatus JCM5810 isolated from chicken intestines, and was substantially variable at the N-terminal and middle regions.	Nitrogen	308-309	synaptotagmin like 2	Homo sapiens	41-45
32778254-1	2020	A Fenton-like reaction and anaerobic ammonium oxidation (anammox) were combined to construct a novel process named FenTaMox for removing nitrogen (N) and organic carbon (measured as chemical oxidation demand (COD)).	Nitrogen	137-145	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	209-212
33016396-6	2020	Nitrate N and total N removal rates averaged 1,500 and 1,440 kg N ha-1  yr-1 , respectively, with the slightly lower total N removal rates reflecting a small net export of reduced N (averaging 66 kg N ha-1  yr-1 ).	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	64-76
33016396-6	2020	Nitrate N and total N removal rates averaged 1,500 and 1,440 kg N ha-1  yr-1 , respectively, with the slightly lower total N removal rates reflecting a small net export of reduced N (averaging 66 kg N ha-1  yr-1 ).	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	199-211
31752354-0	2019	WWOX Possesses N-Terminal Cell Surface-Exposed Epitopes WWOX7-21 and WWOX7-11 for Signaling Cancer Growth Suppression and Prevention In Vivo.	Nitrogen	15-16	WW domain-containing oxidoreductase	Mus musculus	0-4
31693344-8	2019	The previous characterization of HSNO/SNO- and SSNO- is critically discussed based on the available chemical and spectroscopic evidence (mass spectrometry, UV-vis, 15N NMR, Fourier transform infrared), together with computational studies including quantum mechanics/molecular mechanics molecular dynamics simulations that provide a structural and UV-vis description of the solvatochromic properties of cis-SSNO- acting as an electron donor in water, alcohols, and aprotic acceptor solvents.	Nitrogen	164-167	strawberry notch homolog 1	Homo sapiens	34-37
31863529-3	2020	N-terminal proline exists in more than 300 proteins in Saccharomyces cerevisiae, but only three of them are the gluconeogenic enzymes; isocitrate lyase (Icl1), fructose-1,6-bisphosphatase (Fbp1), and malate dehydrogenase (Mdh2).	Nitrogen	0-1	isocitrate lyase 1	Saccharomyces cerevisiae S288C	153-157
32778254-1	2020	A Fenton-like reaction and anaerobic ammonium oxidation (anammox) were combined to construct a novel process named FenTaMox for removing nitrogen (N) and organic carbon (measured as chemical oxidation demand (COD)).	Nitrogen	147-148	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	209-212
31863529-3	2020	N-terminal proline exists in more than 300 proteins in Saccharomyces cerevisiae, but only three of them are the gluconeogenic enzymes; isocitrate lyase (Icl1), fructose-1,6-bisphosphatase (Fbp1), and malate dehydrogenase (Mdh2).	Nitrogen	0-1	fructose 1,6-bisphosphate 1-phosphatase	Saccharomyces cerevisiae S288C	189-193
32989641-6	2020	Decreased levels of Ste12 protein were also observed in these pseudohyphal-defective mutant cells under filamentous-inducing low nitrogen conditions.	Nitrogen	129-137	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	20-25
33104960-3	2020	Here, we describe expression and purification of a recombinant plant LRR-RLK ectodomain MIK1 using a modified baculovirus-mediated expression system with subsequent N-linked glycosylation analysis using LC-MS/MS and computational sequence-based analyses.	Nitrogen	165-166	receptor lectin kinase	Arabidopsis thaliana	73-76
32161097-6	2020	The P2 N-glycosylated extracellular membrane attack complex/perforin domain and the P2 domain independently associate with the extracellular regions of IFNAR1 and IFNAR2, respectively, in resting MEFs.	Nitrogen	7-8	interferon (alpha and beta) receptor 1	Mus musculus	152-158
31621910-4	2020	Gasdermin D (GSDMD) has been proved to be a substrate of inflammatory caspases (caspase-1/4/5/11), and the cleaved N-terminal domain of GSDMD oligomerizes to form cytotoxic pores on the plasma membrane.	Nitrogen	115-116	gasdermin D	Homo sapiens	0-11
31621910-4	2020	Gasdermin D (GSDMD) has been proved to be a substrate of inflammatory caspases (caspase-1/4/5/11), and the cleaved N-terminal domain of GSDMD oligomerizes to form cytotoxic pores on the plasma membrane.	Nitrogen	115-116	gasdermin D	Homo sapiens	13-18
31621910-4	2020	Gasdermin D (GSDMD) has been proved to be a substrate of inflammatory caspases (caspase-1/4/5/11), and the cleaved N-terminal domain of GSDMD oligomerizes to form cytotoxic pores on the plasma membrane.	Nitrogen	115-116	gasdermin D	Homo sapiens	136-141
31670612-6	2020	TRPA1 has been reported to be activated by cold, heat, and mechanical stimuli, and its function is modulated by multiple factors, including Ca2+, trace metals, pH, and reactive oxygen, nitrogen, and carbonyl species.	Nitrogen	185-193	transient receptor potential cation channel subfamily A member 1	Homo sapiens	0-5
31899547-0	2020	A mycorrhiza-specific H+ -ATPase is essential for arbuscule development and symbiotic phosphate and nitrogen uptake.	Nitrogen	100-108	plasma membrane ATPase 1	Solanum lycopersicum	22-32
31996435-4	2020	The glycoprotein (GPC) gene is primarily responsible for attenuation of the Can strain, and we have shown that the absence of an N-linked glycosylation motif in the subunit G1 of the glycoprotein complex of Can, which is otherwise present in the wild-type pathogenic JUNV, causes GPC retention in the endoplasmic reticulum (ER).	Nitrogen	129-130	glycoprotein precursor	Argentinian mammarenavirus	18-21
32210821-7	2020	Administration of recombinant FGF21 to cisplatin-induced AKI mice resulted in significantly decreased blood urea nitrogen (BUN) and serum creatinine levels, as well as significantly reduced protein levels of kidney injury molecule-1 (TIM-1), C-caspase 3, and Bax.	Nitrogen	113-121	fibroblast growth factor 21	Mus musculus	30-35
32608629-5	2020	The total annual runoff in the Shipanqiu small watershed was 8.02x104 m3, and the annual total nitrogen loss flux was 5.04 kg hm-2, of which nitrate nitrogen (2.54 kg hm-2) was the main part.	Nitrogen	95-103	cholinergic receptor muscarinic 2	Homo sapiens	126-130
32608629-5	2020	The total annual runoff in the Shipanqiu small watershed was 8.02x104 m3, and the annual total nitrogen loss flux was 5.04 kg hm-2, of which nitrate nitrogen (2.54 kg hm-2) was the main part.	Nitrogen	149-157	cholinergic receptor muscarinic 2	Homo sapiens	167-171
31996372-3	2020	Alternative splicing of MOCS1 within exons 1 and 9 produces four different N-terminal and three different C-terminal products (type I-III).	Nitrogen	75-76	molybdenum cofactor synthesis 1	Homo sapiens	24-29
31996378-9	2020	Co-precipitation assays revealed that Fry uses its N-terminal 1-2400 amino-acid-long region to bind to YAP.	Nitrogen	51-52	Yes1 associated transcriptional regulator	Homo sapiens	103-106
31996378-10	2020	Expression of full-length FRY or its 1-2400 N-terminal fragment restored YAP cytoplasmic localization in FRY-knockout cells.	Nitrogen	44-45	Yes1 associated transcriptional regulator	Homo sapiens	73-76
32138379-5	2020	Differential fluorescence-activated cell sorting demonstrated reduced surface expression of N-glycosylated CD109, EGFR, DPP4, and rhMUC1.	Nitrogen	92-93	CD109 molecule	Homo sapiens	107-112
31771419-6	2020	The expression of Gmppc2 protein was negatively regulated by the application of a nitrogen fertilizer, which suppressed nodule formation.	Nitrogen	82-90	phosphoenolpyruvate carboxylase, housekeeping isozyme-like	Glycine max	18-24
31771419-7	2020	These results imply that Gmppc2 is involved in the metabolism of nitrogen originated from nodules into seeds, and Gmppc2 might be applicable as a biomarker of seed protein content.Abbreviations: PEP: phosphoenolpyruvate; PEPC: phosphoenolpyruvate carboxylase; RNA-Seq: RNA sequencing; PCA: principal component analysis; SE: standard error.	Nitrogen	65-73	phosphoenolpyruvate carboxylase, housekeeping isozyme-like	Glycine max	25-31
31945542-2	2020	In vitro, dL traps the major base excision DNA repair enzyme DNA polymerase beta (Polbeta) in covalent DNA-protein crosslinks (DPC) via the enzyme"s N-terminal lyase activity acting on 5"-deoxyribose-5-phosphate residues.	Nitrogen	44-45	DNA polymerase beta	Homo sapiens	61-80
31599087-2	2020	HbA1c is formed by the irreversible modification of N-terminal alpha-amino group of beta globin chain with glucose via Amadori rearrangement.	Nitrogen	52-53	hemoglobin subunit alpha 1	Homo sapiens	0-4
32005391-2	2020	One of the first cloned RLKs is the Arabidopsis receptor kinase FLAGELLIN SENSING 2 (FLS2), which specifically recognizes a conserved 22 amino acid N-terminal sequence of Pseudomonas syringae pv.tomato DC3000 (Pst) flagellin protein (flg22).	Nitrogen	72-73	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	85-89
32017556-0	2020	Bioelectrocatalytic Conversion from N2 to Chiral Amino Acids in a H2/alpha-Keto Acid Enzymatic Fuel Cell.	Nitrogen	36-38	H2A clustered histone 18	Homo sapiens	11-12
32017556-0	2020	Bioelectrocatalytic Conversion from N2 to Chiral Amino Acids in a H2/alpha-Keto Acid Enzymatic Fuel Cell.	Nitrogen	36-38	H2A clustered histone 18	Homo sapiens	66-74
32017556-4	2020	In this study, a H2/alpha-keto acid EFC was developed for the conversion from chemically inert nitrogen gas to chiral amino acids, powered by H2 oxidation.	Nitrogen	95-103	H2A clustered histone 18	Homo sapiens	15-16
32009135-2	2020	Then, a first new porous d-p heterometallic MOF (HMOF), namely {[PbZn(L)2] DMA H2O}n (2), was yielded via Zn(ii) ions and MOF 1 as the precursor because of the different coordination affinity of oxygen and nitrogen atoms with various metal ions.	Nitrogen	206-214	lysine acetyltransferase 8	Homo sapiens	29-47
32009135-2	2020	Then, a first new porous d-p heterometallic MOF (HMOF), namely {[PbZn(L)2] DMA H2O}n (2), was yielded via Zn(ii) ions and MOF 1 as the precursor because of the different coordination affinity of oxygen and nitrogen atoms with various metal ions.	Nitrogen	206-214	lysine acetyltransferase 8	Homo sapiens	49-53
31957979-3	2020	The in situ ion substitution of Fe3+ in a nitrogen-containing MOF (ZIF-8) allows the Fe-heteroatoms to be uniformly distributed in the MOF precursor, and the assembly of Fe-doped ZIF-8 nano-crystals with graphene-oxide and in situ reduction of graphene-oxide afford a sandwiched-like Fe-doped ZIF-8/graphene heterostructure.	Nitrogen	42-50	lysine acetyltransferase 8	Homo sapiens	62-65
31957979-3	2020	The in situ ion substitution of Fe3+ in a nitrogen-containing MOF (ZIF-8) allows the Fe-heteroatoms to be uniformly distributed in the MOF precursor, and the assembly of Fe-doped ZIF-8 nano-crystals with graphene-oxide and in situ reduction of graphene-oxide afford a sandwiched-like Fe-doped ZIF-8/graphene heterostructure.	Nitrogen	42-50	lysine acetyltransferase 8	Homo sapiens	135-138
31844913-1	2020	A novel fed-batch strategy based on carbon/nitrogen (C/N) ratio in a microbial co-culture production medium broth was carried out in a biocalorimeter for improved production of poly (3-hydroxybutyrate) (PHB).	Nitrogen	55-56	prohibitin 1	Homo sapiens	203-206
31593356-0	2020	Trypanosoma cruzi cleaves galectin-3 N-terminal domain to suppress its innate microbicidal activity.	Nitrogen	37-38	galectin 3	Homo sapiens	26-36
31593356-4	2020	Herein we describe a molecular mechanism developed by T. cruzi to proteolytically process galectin-3 that generates a truncated form of the protein lacking its N-terminal domain - required for protein oligomerization - but still conserves a functional carbohydrate recognition domain (CRD).	Nitrogen	160-161	galectin 3	Homo sapiens	90-100
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	protein tyrosine kinase 2	Homo sapiens	158-161
31596952-0	2020	Differential phosphorylation of the N-terminal extension regulates phytochrome B signaling.	Nitrogen	36-37	phytochrome B	Arabidopsis thaliana	67-80
31596952-4	2020	In this study we identified several serine/threonine residues on the N-terminal extension (NTE) of Arabidopsis thaliana phyB that are differentially phosphorylated in response to light and temperature and examined transgenic plants expressing non-phosphorylatable and phosphomimic phyB mutants.	Nitrogen	69-70	phytochrome B	Arabidopsis thaliana	120-124
31839525-2	2020	We have considered the disordered region that connects the N- and C-terminal halves in many eukaryotic ABC transporters, allowing all four consensus functional domains to be linked.	Nitrogen	59-60	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	103-106
30902024-8	2020	The catalytic efficiency (kcat/Km) for meperidine N-demethylation was similar between recombinant CYP2B6 and CYP2C19, but markedly lower by CYP3A4.	Nitrogen	50-51	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	98-104
31934745-4	2020	Although Y- and Sc-based nanomaterials are generally inactive to room-temperature electrochemical reactions, Y1/NC and Sc1/NC SACs exhibit catalytic activities to nitrogen reduction reaction and carbon dioxide reduction reaction due to the modulation of the local electronic structure of Y/Sc single atoms by N and C coordination.	Nitrogen	163-171	transcription factor 19	Homo sapiens	119-122
31880451-2	2020	Here, 15N/13C spin-echo magic-angle spinning (MAS) solid-state NMR experiments are applied to "view" intermolecular CH   N hydrogen bonding in two selectively labelled organic compounds, 4-[15N] cyano-4"-[13C2] ethynylbiphenyl (1) and [15N3,13C6]-2,4,6-triethynyl-1,3,5-triazine (2).	Nitrogen	8-9	chimerin 1	Homo sapiens	116-122
31998401-8	2020	Similarly, fatty acid synthesis in pigs from the L-BCAA group was also lower than those from the N-BCAA group with the decrease of lipogenic genes (ACACA in ventral, ACACA and FASN in dorsal fat, ACACA, FASN, SREBP-1c in liver) and the increase of lipolysis genes (ATGL, CPT-1A CD36, FABP4 in ventral fat and HSL, ATGL, CPT-1A in dorsal fat, CPT-1A) (P &lt; 0.05).	Nitrogen	97-98	fatty acid synthase	Sus scrofa	176-180
31934853-5	2020	The module at the N-terminus of Notch ligand (MNNL) of Dll4 is inherently advantageous over Dll1.	Nitrogen	18-19	delta like canonical Notch ligand 4	Mus musculus	55-59
31754723-6	2020	We show that the N-terminal 152 amino-acid residue segment of DHX30, denoted DHX30N, possesses all the antiviral activity of DHX30 and contains a dsRNA-binding domain, and that the NS1-DHX30 interaction in vivo requires the dsRNA-binding activity of both DHX30N and the NS1 RBD.	Nitrogen	17-18	DExH-box helicase 30	Homo sapiens	62-67
31754723-6	2020	We show that the N-terminal 152 amino-acid residue segment of DHX30, denoted DHX30N, possesses all the antiviral activity of DHX30 and contains a dsRNA-binding domain, and that the NS1-DHX30 interaction in vivo requires the dsRNA-binding activity of both DHX30N and the NS1 RBD.	Nitrogen	17-18	DExH-box helicase 30	Homo sapiens	77-82
31754723-6	2020	We show that the N-terminal 152 amino-acid residue segment of DHX30, denoted DHX30N, possesses all the antiviral activity of DHX30 and contains a dsRNA-binding domain, and that the NS1-DHX30 interaction in vivo requires the dsRNA-binding activity of both DHX30N and the NS1 RBD.	Nitrogen	17-18	DExH-box helicase 30	Homo sapiens	77-82
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	62-65
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31696206-6	2019	A TMCC3 mutant lacking the N-terminal coiled-coil domain abolished localization to the three-way junctions, suggesting that TMCC3 localized independently of binding to atlastins.	Nitrogen	27-28	transmembrane and coiled-coil domain family 3	Homo sapiens	2-7
31727943-1	2019	Mixed Lineage Kinase domain-Like (MLKL), a key player in necroptosis, is a multi-domain protein with an N-terminal 4 helical bundle (4HB) and a pseudokinase domain (PsK) connected by brace helices.	Nitrogen	104-105	mixed lineage kinase domain like pseudokinase	Homo sapiens	0-32
31727943-1	2019	Mixed Lineage Kinase domain-Like (MLKL), a key player in necroptosis, is a multi-domain protein with an N-terminal 4 helical bundle (4HB) and a pseudokinase domain (PsK) connected by brace helices.	Nitrogen	104-105	mixed lineage kinase domain like pseudokinase	Homo sapiens	34-38
31631027-2	2019	Particularly intriguing are the large N-terminal deletions of ATRX (Alpha Thalassemia/Mental Retardation, X-linked) that generate in-frame fusion (IFF) proteins devoid of key chromatin interaction domains, while retaining the SWI/SNF-like helicase region.	Nitrogen	38-39	ATRX chromatin remodeler	Homo sapiens	62-66
31290877-4	2019	The porous structure facilitates the uptake of N2 and activated samples give rise to BET surface areas of &gt;1000 m2 g-1.	Nitrogen	47-49	delta/notch like EGF repeat containing	Homo sapiens	85-88
31699039-9	2019	Further molecular modeling, docking and simulation approaches revealed significant conformational changes in the N-terminus region of normal to mutant CTNNB1 gene critical for binding with Glycogen synthase kinase 3-B (GSK3) and transducin containing protein1 (TrCp1).	Nitrogen	113-114	glycogen synthase kinase 3 beta	Homo sapiens	189-217
31699039-9	2019	Further molecular modeling, docking and simulation approaches revealed significant conformational changes in the N-terminus region of normal to mutant CTNNB1 gene critical for binding with Glycogen synthase kinase 3-B (GSK3) and transducin containing protein1 (TrCp1).	Nitrogen	113-114	glycogen synthase kinase 3 beta	Homo sapiens	219-223
31550152-8	2019	Furthermore, an N-alkylimine, which shows excellent reactivity and selectivity in reactions with DSI, reveals an enlarged structural space in complexes with the chiral phosphoric acid TRIP as potential explanation of its reduced reactivity and selectivity.	Nitrogen	16-28	TRAF interacting protein	Homo sapiens	184-188
31087782-2	2019	Herein, a novel nanoflower-like electrocatalyst comprising few-layer nitrogen-doped graphene-encapsulated nickel-copper alloy directly on a porous nitrogen-doped graphic carbon framework (denoted as Nix Cuy @ NG-NC) is successfully synthesized using a facile and scalable method through calcinating the carbon, copper, and nickel hydroxy carbonate composite under inert atmosphere.	Nitrogen	69-77	BCL2 interacting protein 3 like	Homo sapiens	199-202
31087782-2	2019	Herein, a novel nanoflower-like electrocatalyst comprising few-layer nitrogen-doped graphene-encapsulated nickel-copper alloy directly on a porous nitrogen-doped graphic carbon framework (denoted as Nix Cuy @ NG-NC) is successfully synthesized using a facile and scalable method through calcinating the carbon, copper, and nickel hydroxy carbonate composite under inert atmosphere.	Nitrogen	147-155	BCL2 interacting protein 3 like	Homo sapiens	199-202
31833694-8	2019	The results of path analysis showed that NAM addition weakened the direct effect of soil NH4+-N pool on NO3--N pool but enhanced the indirect effects of FN pool on NO3--N pool through affecting NH4+-N pool.	Nitrogen	104-110	NAC domain-containing protein 20	Triticum aestivum	41-44
31833694-8	2019	The results of path analysis showed that NAM addition weakened the direct effect of soil NH4+-N pool on NO3--N pool but enhanced the indirect effects of FN pool on NO3--N pool through affecting NH4+-N pool.	Nitrogen	164-170	NAC domain-containing protein 20	Triticum aestivum	41-44
31833694-11	2019	In summary, through double regulation for N release and transformation in soil, NAM delayed the appearance time of soil NH4+-N peak and retarded its transformation into NO3--N, and increased the roles of MBN and FN in supplying N, thereby increased crop yield and N-fertilizer use efficiency.	Nitrogen	169-175	NAC domain-containing protein 20	Triticum aestivum	80-83
31661879-1	2019	Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human cis-prenyltransferase complex, synthesizing the glycosyl carrier precursor for N-linked protein glycosylation.	Nitrogen	174-175	dehydrodolichyl diphosphate synthase subunit	Homo sapiens	0-36
31661879-1	2019	Dehydrodolichyl diphosphate synthase (DHDDS) is the catalytic subunit of the heteromeric human cis-prenyltransferase complex, synthesizing the glycosyl carrier precursor for N-linked protein glycosylation.	Nitrogen	174-175	dehydrodolichyl diphosphate synthase subunit	Homo sapiens	38-43
31661879-2	2019	Consistent with the important role of N-glycosylation in protein biogenesis, DHDDS mutations result in human diseases.	Nitrogen	38-39	dehydrodolichyl diphosphate synthase subunit	Homo sapiens	77-82
31608911-4	2019	The peak, at a frequency of about 1 MHz, shows a peculiar temperature behavior at the NTB to N transition, reminiscent of the soft mode at the transition from the SmA to the SmC phase.	Nitrogen	86-87	survival of motor neuron 1, telomeric	Homo sapiens	163-166
31339661-3	2019	Of the composite materials that were tested, [BMIM][PF6 ]/MIL-53(Al) exhibited the largest increase in CO2 /CH4 selectivity, 2.8-times higher than that of pristine MIL-53(Al), whilst [BMIM][MeSO4 ]/MIL-53(Al) exhibited the largest increase in CO2 /N2 selectivity, 3.3-times higher than that of pristine MIL-53(Al).	Nitrogen	248-250	sperm associated antigen 17	Homo sapiens	52-55
31339661-4	2019	A comparison of the CO2 separation potentials of the IL/MOF composites showed that the [BMIM][BF4 ]- and [BMIM][PF6 ]-incorporated MIL-53(Al) composites both showed enhanced CO2 /N2 and CO2 /CH4 selectivities at pressures of 1-5 bar compared to composites of CuBTC and ZIF-8 with the same ILs.	Nitrogen	179-181	sperm associated antigen 17	Homo sapiens	112-115
31696472-9	2019	Inhibition of lncRNA AOC4P expression also can result in the decreased expression levels of extracellular-signal-regulated kinase 1 (ERK1), c-Jun N-terminal kinases (JNK) and p38 proteins.	Nitrogen	18-19	amine oxidase copper containing 4, pseudogene	Homo sapiens	21-26
31632982-0	2019	The Role of Post-translational Modifications on the Energy Landscape of Huntingtin N-Terminus.	Nitrogen	83-84	huntingtin	Homo sapiens	72-82
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	CPAT1	Homo sapiens	74-77
31586624-8	2020	The protective effect of Apelin-36 was also associated with the inhibition of the apoptosis signal-regulating kinase 1 (ASK1)/c-Jun N-terminal kinase(JNK) signaling pathway and inactivation of caspase-3.	Nitrogen	132-133	apelin	Mus musculus	25-31
31586624-8	2020	The protective effect of Apelin-36 was also associated with the inhibition of the apoptosis signal-regulating kinase 1 (ASK1)/c-Jun N-terminal kinase(JNK) signaling pathway and inactivation of caspase-3.	Nitrogen	132-133	jun proto-oncogene	Mus musculus	126-131
31769197-3	2020	The GATA1 protein contains two zinc finger domains and an N-terminal transactivation domain.	Nitrogen	58-59	GATA binding protein 1	Mus musculus	4-9
31769197-4	2020	GATA1 translation results in the production of the full-length protein and of a shorter variant (GATA1s) lacking the N-terminal transactivation domain, which is functionally deficient in supporting erythropoiesis.	Nitrogen	117-118	GATA binding protein 1	Mus musculus	0-5
31759040-9	2020	The activated N-terminal Gasdermin D molecule form pores in the infected cells leading to their pyroptosis.	Nitrogen	14-15	gasdermin D	Homo sapiens	25-36
31441600-4	2019	METHODS: In this study, TET2 expression of samples cryopreserved in the liquid nitrogen from January 1, 2007 through December 31, 2011 was retrospectively analyzed in 136 newly diagnosed ALL patients by real-time polymerase chain reaction (PCR) assay.	Nitrogen	79-87	tet methylcytosine dioxygenase 2	Homo sapiens	24-28
31377676-4	2019	RhIL-17A and rhIL-17F shared 96.8% and 93.9% amino acid sequence identity with human IL-17A (huIL-17A) and IL-17F (huIL-17F) respectively and the sequences also shared one N-glycosylation site and six conserved cysteine residues with huIL-17A and huIL-17F.	Nitrogen	172-173	interleukin 17F	Homo sapiens	15-21
32911634-3	2020	Xanthine oxidoreductase (XOR) activities produce uric acid, as well as reactive oxygen and nitrogen species, which all may be relevant to such equilibrium.	Nitrogen	91-99	xanthine dehydrogenase	Homo sapiens	0-23
31575916-6	2019	We next determined that, after SCI, VDAC1 undergoes conformational changes, including oligomerization and N-terminal exposition, which are important steps in the triggering of apoptotic signaling.	Nitrogen	106-107	voltage dependent anion channel 1	Homo sapiens	36-41
31897196-8	2020	Results showed that FIBCD1 expression was higher in HCC and was associated with tumor diameter (P=0.002), tumor number (P=0.001), tumor node metastasis stage (P&lt;0.001), primary tumor (T; P&lt;0.001), lymph node metastases (N; P=0.002), distant metastases (M; P=0.023), differentiation degree (P=0.003), vascular invasion (P&lt;0.001) and liver cirrhosis (P=0.011).	Nitrogen	226-227	fibrinogen C domain containing 1	Homo sapiens	20-26
31713634-6	2019	Further analysis confirmed that NuRD is required for ectopic CENP-A incorporation, and RbAp48 and MTA1-like subunits of NuRD together with the N-terminal tail of CENP-A mediate the interaction.	Nitrogen	32-33	centromere identifier	Drosophila melanogaster	61-67
31713634-6	2019	Further analysis confirmed that NuRD is required for ectopic CENP-A incorporation, and RbAp48 and MTA1-like subunits of NuRD together with the N-terminal tail of CENP-A mediate the interaction.	Nitrogen	32-33	centromere identifier	Drosophila melanogaster	162-168
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	serine incorporator 5	Homo sapiens	200-207
32911634-3	2020	Xanthine oxidoreductase (XOR) activities produce uric acid, as well as reactive oxygen and nitrogen species, which all may be relevant to such equilibrium.	Nitrogen	91-99	xanthine dehydrogenase	Homo sapiens	25-28
32944295-3	2020	We model the trimeric Spike protein, including flexible loops and all N-glycosylation sites, in order to elucidate accessible epitopes for antibody-based diagnostics, therapeutics and vaccine development.	Nitrogen	70-71	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	22-27
31654685-4	2019	As a proof-of-concept, the protein binder composed of LRR (Leucine-rich repeat) modules was genetically fused to the N-terminus of Glucagon-like Peptide-1 (GLP-1).	Nitrogen	117-118	glucagon	Mus musculus	131-154
31654685-4	2019	As a proof-of-concept, the protein binder composed of LRR (Leucine-rich repeat) modules was genetically fused to the N-terminus of Glucagon-like Peptide-1 (GLP-1).	Nitrogen	117-118	glucagon	Mus musculus	156-161
31439327-6	2019	RESULTS: Blood urea nitrogen and serum creatinine levels were significantly lower in the IR-AAT group than in the IR group.	Nitrogen	20-28	serine (or cysteine) preptidase inhibitor, clade A, member 1B	Mus musculus	92-95
32790377-8	2020	Moreover, when pH > pKa(EP- ), EP- deprotonates to dianionic EP2-, which rapidly eliminates N2 to CP2-, inducing chemiexcitation.	Nitrogen	92-94	prostaglandin E receptor 2	Homo sapiens	61-64
31561412-1	2019	The papain-like cysteine protease 2 (PLP2) within the N-terminus of the porcine reproductive and respiratory syndrome virus (PRRSV) nsp2 replicase protein specifies a deubiquitinating enzyme (DUB), but its biochemical properties and the role in infection have remained poorly defined.	Nitrogen	54-55	reticulon 2	Homo sapiens	132-136
31572782-7	2019	The interaction between intact FcepsilonRIalpha and the lectin hGal3, also studied here, confirms this hypothesis and opens new avenues for the detection of specific N-glycan epitopes and for the studies of glycoprotein-receptor interactions mediated by N-glycans.	Nitrogen	166-167	galectin 3	Homo sapiens	63-68
31572782-7	2019	The interaction between intact FcepsilonRIalpha and the lectin hGal3, also studied here, confirms this hypothesis and opens new avenues for the detection of specific N-glycan epitopes and for the studies of glycoprotein-receptor interactions mediated by N-glycans.	Nitrogen	254-255	galectin 3	Homo sapiens	63-68
31763647-1	2019	We report a multi-shelled two-dimensional metal-organic framework (MOF), which is transferred to a Co/Ni-embedded bimetallic N-doped porous carbon.	Nitrogen	102-103	lysine acetyltransferase 8	Homo sapiens	42-71
31587919-7	2019	Reduction of DDX3X increases DPR levels in C9ORF72-ALS/FTD patient cells and enhances (GGGGCC)n-mediated toxicity in Drosophila.	Nitrogen	8-9	DEAD-box helicase 3 X-linked	Homo sapiens	13-18
31587919-7	2019	Reduction of DDX3X increases DPR levels in C9ORF72-ALS/FTD patient cells and enhances (GGGGCC)n-mediated toxicity in Drosophila.	Nitrogen	8-9	C9orf72-SMCR8 complex subunit	Homo sapiens	43-50
32402213-7	2020	Studies with primary lung epithelial cells also demonstrated that Chi3l1 inhibited, whereas IL-13 stimulated, N-glycosylation as evidenced by the ability of Chi3l1 to inhibit and IL-13 to stimulate the subunits of the oligosaccharide complex A and B (STT3A and STT3B).	Nitrogen	110-111	chitinase 3 like 1	Homo sapiens	66-72
32402213-8	2020	These studies demonstrate that N-glycosylation is a critical determinant of Chi3l1 and IL-13 binding to IL-13Ralpha2, and highlight the ability of Chi3l1 and IL-13 to alter key elements of the N-glycosylation apparatus in a manner that would augment their respective binding.	Nitrogen	31-32	chitinase 3 like 1	Homo sapiens	76-82
31702909-8	2019	A designed CD19 variant with all N-linked glycosylation sites removed successfully bound antibody in the yeast display context, which provides a lead for aglycosylated applications.	Nitrogen	33-34	CD19 molecule	Homo sapiens	11-15
31673231-5	2019	Although higher expression of DR4 was significantly associated with lower T, N and TNM stages, neither DR4 nor DR5 expression meaningfully influenced overall survival rate.	Nitrogen	77-78	TNF receptor superfamily member 10a	Homo sapiens	30-33
31541188-4	2019	Each hPAH monomer comprises an N-terminal regulatory, a central catalytic and a C-terminal oligomerisation domain.	Nitrogen	31-32	phenylalanine hydroxylase	Homo sapiens	5-9
31794565-5	2019	Mutational analysis of MARK2 revealed that the N-terminal kinase domain of MARK2 is sufficient for phosphorylation of both consensus and variant zetaXKXGSXXNPsi sites.	Nitrogen	47-48	microtubule affinity regulating kinase 2	Homo sapiens	23-28
31794565-5	2019	Mutational analysis of MARK2 revealed that the N-terminal kinase domain of MARK2 is sufficient for phosphorylation of both consensus and variant zetaXKXGSXXNPsi sites.	Nitrogen	47-48	microtubule affinity regulating kinase 2	Homo sapiens	75-80
32402213-8	2020	These studies demonstrate that N-glycosylation is a critical determinant of Chi3l1 and IL-13 binding to IL-13Ralpha2, and highlight the ability of Chi3l1 and IL-13 to alter key elements of the N-glycosylation apparatus in a manner that would augment their respective binding.	Nitrogen	31-32	interleukin 13 receptor subunit alpha 2	Homo sapiens	104-116
31594790-0	2019	N-Terminal modification of Arg-Leu-Tyr-Glu, a VEGFR-2 antagonist, improves anti-tumor activity by increasing its stability against serum peptidases.	Nitrogen	0-1	kinase insert domain protein receptor	Mus musculus	46-53
32402213-8	2020	These studies demonstrate that N-glycosylation is a critical determinant of Chi3l1 and IL-13 binding to IL-13Ralpha2, and highlight the ability of Chi3l1 and IL-13 to alter key elements of the N-glycosylation apparatus in a manner that would augment their respective binding.	Nitrogen	193-194	interleukin 13 receptor subunit alpha 2	Homo sapiens	104-116
31594790-10	2019	SIGNIFICANCE STATEMENT: The results of this study demonstrate that the N-terminal acetylation of the tetrapeptide RLYE (Ac-RLYE), a novel VEGFR-2 inhibitor, significantly improves its serum stability, anti-angiogenic activity, and vascular normalizing potency, resulting in enhanced therapeutic effect on solid tumors.	Nitrogen	3-4	kinase insert domain protein receptor	Mus musculus	138-145
32402213-8	2020	These studies demonstrate that N-glycosylation is a critical determinant of Chi3l1 and IL-13 binding to IL-13Ralpha2, and highlight the ability of Chi3l1 and IL-13 to alter key elements of the N-glycosylation apparatus in a manner that would augment their respective binding.	Nitrogen	193-194	chitinase 3 like 1	Homo sapiens	147-153
33382965-6	2020	RESULTS: As DKD worsened, the level of serum MRP8/14 increased gradually, and MRP8/14 has a significantly positive correlation with ACR (r = 0.349, P = 0.002), body mass index (BMI) (r = 0.288, P = 0.009), serum creatinine (Cre) (r = 0.392, P < 0.001), blood urine nitrogen (BUN) (r = 0.333, P = 0.003), systolic blood pressure (SBP) (r = 0.301, P = 0.007), and a negative correlation with the estimated glomerular filtration rate (eGFR) (r = -0.478, P < 0.001).	Nitrogen	265-273	S100 calcium binding protein A8	Homo sapiens	78-85
31550607-1	2019	Wild type (WT) HIV-1 envelope (Env) protein cytoplasmic tails (CTs) appear to be composed of membrane-proximal, N-terminal unstructured regions, and three C-terminal amphipathic helices.	Nitrogen	112-113	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	31-34
31319149-3	2019	BET surface area via nitrogen adsorption is shown to be erroneously high due to a structural swelling and adsorbate encapsulation effect occurring throughout the BET range and which should preclude the use of BET theory.	Nitrogen	21-29	delta/notch like EGF repeat containing	Homo sapiens	0-3
31319149-5	2019	The disparity between nitrogen and krypton adsorption is greater for the di-hydrate form: the mean average BET surface area of 10 samples from the same di-hydrate containing batch are 23.18 m2g-1 via nitrogen adsorption and 6.78 m2g-1 via krypton.	Nitrogen	200-208	delta/notch like EGF repeat containing	Homo sapiens	107-110
31367714-1	2019	Monocarbonyl complexes [RuCl2(CO)(PR3)(NN)] (R = Cy, NN = en 1, ampy 2; R = iPr; NN = en 3) have been prepared in a one pot reaction from [RuCl2(CO)(dmf)(PPh3)2], PR3 and the NN ligand in CH2Cl2.	Nitrogen	39-41	proteinase 3	Homo sapiens	34-37
31840463-4	2019	The results showed that, compared with no-straw returning treatment, the treatments of straw returning combined nitrogen fertilizer with 300 and 450 kg hm-2 reduced soil bulk density (0-20 cm) by 3.3% and 5.4%, but increased soil porosity by 3.7% and 7.1%, respectively.	Nitrogen	112-120	Putative anthocyanidin reductase	Zea mays	152-156
31840463-5	2019	Straw returning combined with nitrogen with 300 kg hm-2 and 450 kg hm-2 was the best treatment which increased soil organic matter content, available K, P, alkaline N and total N in 0-40 cm soil layer.	Nitrogen	30-38	Putative anthocyanidin reductase	Zea mays	51-55
32380391-5	2020	When the N fertilizer application level was optimal (403-475 kg N ha-1), the NUE in the CPS (NUEc) decreased sharply, resulting in a higher N cost than that observed at larger scales.	Nitrogen	9-10	solute carrier family 9 member B1	Homo sapiens	64-70
31840463-5	2019	Straw returning combined with nitrogen with 300 kg hm-2 and 450 kg hm-2 was the best treatment which increased soil organic matter content, available K, P, alkaline N and total N in 0-40 cm soil layer.	Nitrogen	30-38	Putative anthocyanidin reductase	Zea mays	67-71
31840463-6	2019	Compared with the non-returning treatment, straw returning combined with nitrogen fertilizer 300 kg hm-2 significantly increased soil water storage by 13.6% and 22.1%, increased maize yield by 31.1% and 46.0 % in 2017 and 2018, respectively.	Nitrogen	73-81	Putative anthocyanidin reductase	Zea mays	100-104
31840463-8	2019	Curve fitting showed that the optimum amount of nitrogen fertilizer was 260 kg hm-2.	Nitrogen	48-56	Putative anthocyanidin reductase	Zea mays	79-83
31404498-0	2019	Nitrogen-Doped Hollow Copolymer Tube via Template-Free Asynchronous Polymerization with Highly Selective Separation of Hydrophilic Dipeptide for Enhancing Inhibitory Activity of Angiotensin Converting Enzyme.	Nitrogen	0-8	LOC101737600	Bombyx mori	178-207
31572358-7	2019	Remarkably, ACPA-IgG are heavily N-glycosylated in the variable domain due to somatic mutations that generate abundant N-glycosylation consensus sequences.	Nitrogen	33-34	proteinase 3	Homo sapiens	12-16
31572358-7	2019	Remarkably, ACPA-IgG are heavily N-glycosylated in the variable domain due to somatic mutations that generate abundant N-glycosylation consensus sequences.	Nitrogen	119-120	proteinase 3	Homo sapiens	12-16
31572358-12	2019	Our analyses revealed an abundance of N-glycosylation sites in ACPA-IgG HC that frequently required multiple mutations and predominated in specific positions.	Nitrogen	38-39	proteinase 3	Homo sapiens	63-67
31572358-13	2019	Based on these data, and taking into account recent insights into the dynamics of the ACPA-response during disease development, we here discuss the hypothesis that N-glycosylation sites in ACPA-IgG variable domains could lead to alternative, possibly antibody affinity-independent selection forces.	Nitrogen	164-165	proteinase 3	Homo sapiens	86-90
31984176-0	2019	Allosteric response to ligand binding: Molecular dynamics study of the N-terminal domains in IP 3 receptor.	Nitrogen	71-72	inositol 1,4,5-trisphosphate receptor type 3	Homo sapiens	93-106
31572358-13	2019	Based on these data, and taking into account recent insights into the dynamics of the ACPA-response during disease development, we here discuss the hypothesis that N-glycosylation sites in ACPA-IgG variable domains could lead to alternative, possibly antibody affinity-independent selection forces.	Nitrogen	164-165	proteinase 3	Homo sapiens	189-193
31984176-3	2019	Here, we conducted molecular dynamics (MD) simulations of the three N-terminal domains of IP3R responsible for IP3 binding (IBC/SD; two domains of the IP3 binding core, IBCbeta and IBCalpha, and suppressor domain, SD) as a model system to study the initial gating stage.	Nitrogen	68-69	inositol 1,4,5-trisphosphate receptor type 3	Homo sapiens	90-94
31780710-4	2019	Interface analysis reveals that N-glycosylation sites 49, 74 and 116 on PD-1 do not contact mAb059c; while N58 in the BC loop is recognized by mAb059c heavy chain CDR1 and CDR2.	Nitrogen	32-33	programmed cell death 1	Homo sapiens	72-76
31774397-6	2019	The MADA motif matches the N-terminal a1 helix of Arabidopsis NLR protein ZAR1, which undergoes a conformational switch during resistosome activation.	Nitrogen	27-28	HOPZ-ACTIVATED RESISTANCE 1	Arabidopsis thaliana	74-78
31443635-10	2019	(n = 19,325), 37.48% were Carb-NS, 47.66% were MDR, and the most common source was skin/wound cultures.	Nitrogen	31-33	syntaxin 8	Homo sapiens	26-30
31420553-0	2019	N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals.	Nitrogen	0-1	neuropilin 1	Homo sapiens	45-57
32034976-4	2020	Our data suggest a new role for the N-terminus of cardiac ELC (N-ELC) in modulation of myosin cross-bridge function in the healthy as well as in HCM myocardium.	Nitrogen	36-37	chemokine (C-C motif) ligand 19, pseudogene 2	Mus musculus	58-61
31305069-4	2019	Benefiting from the strong coupling effect, the N-MoO2/Ni3S2 NF exhibited a high HER performance in basic media, with a small value of the Tafel slope (76 mV dec-1) and a low potential of 517 mV at 1000 mA cm-2, which was superior to that of Pt/C (631 mV at 1000 mA cm-2).	Nitrogen	48-49	deleted in esophageal cancer 1	Homo sapiens	158-163
31751425-5	2019	The facts that phosphorylation of Ser-1072 in FMNL2 has been shown to play a critical role in integrin beta1 internalization mediated by FMNL2 and that Ser-171 in FMNL2 and Ser-174 in FMNL3 are novel putative phosphorylation sites conserved between FMNL2 and FMNL3 indicate that the strategy used in this study is a useful tool for identifying and characterizing physiologically important phosphorylation reactions occurring on N-myristoylated proteins.	Nitrogen	48-49	formin like 3	Homo sapiens	184-189
31751425-5	2019	The facts that phosphorylation of Ser-1072 in FMNL2 has been shown to play a critical role in integrin beta1 internalization mediated by FMNL2 and that Ser-171 in FMNL2 and Ser-174 in FMNL3 are novel putative phosphorylation sites conserved between FMNL2 and FMNL3 indicate that the strategy used in this study is a useful tool for identifying and characterizing physiologically important phosphorylation reactions occurring on N-myristoylated proteins.	Nitrogen	48-49	formin like 3	Homo sapiens	259-264
31511384-14	2019	The two specific thioredoxin subunits of STT3B-OST MAGT1 and TUSC3 were found to be essential for the N-glycosylation of viral GP.	Nitrogen	102-103	tumor suppressor candidate 3	Homo sapiens	61-66
32034976-4	2020	Our data suggest a new role for the N-terminus of cardiac ELC (N-ELC) in modulation of myosin cross-bridge function in the healthy as well as in HCM myocardium.	Nitrogen	36-37	chemokine (C-C motif) ligand 19, pseudogene 2	Mus musculus	63-68
32533721-4	2020	However, N inputs negated the promotional effects of increased precipitation, mainly through suppressing fungal growth and altering soil pH and clay-Mg2+ -OC bridging.	Nitrogen	9-10	mucin 7, secreted	Homo sapiens	149-152
31718088-3	2019	The N-terminal half of CAP has been shown to promote actin filament dynamics by enhancing ADF-/cofilin-mediated actin severing, while the central and C-terminal domains are involved in recharging the depolymerized ADP-G-actin/cofilin complexes with ATP and profilin.	Nitrogen	4-5	destrin, actin depolymerizing factor	Homo sapiens	90-93
31718088-3	2019	The N-terminal half of CAP has been shown to promote actin filament dynamics by enhancing ADF-/cofilin-mediated actin severing, while the central and C-terminal domains are involved in recharging the depolymerized ADP-G-actin/cofilin complexes with ATP and profilin.	Nitrogen	4-5	cofilin 1	Homo sapiens	95-102
31718088-3	2019	The N-terminal half of CAP has been shown to promote actin filament dynamics by enhancing ADF-/cofilin-mediated actin severing, while the central and C-terminal domains are involved in recharging the depolymerized ADP-G-actin/cofilin complexes with ATP and profilin.	Nitrogen	4-5	cofilin 1	Homo sapiens	226-233
31718088-4	2019	We analyzed the ability of the N-terminal fragments of human CAP1 and CAP2 to assist human isoforms of "muscle" (CFL2) and "non-muscle" (CFL1) cofilins in accelerating actin dynamics.	Nitrogen	31-32	cyclase associated actin cytoskeleton regulatory protein 1	Homo sapiens	61-65
30613975-5	2019	Either beta3 -AR activation or its overexpression could increase cellular reactive oxygen species (ROS) and reactive nitrogen species (RNS) levels, in line with significant changes in nitric oxide (NO)-pathway, including increases in the ratios of pNOS3/NOS3 and pGSK-3beta/GSK-3beta, and PKG expression level in cardiomyocytes.	Nitrogen	117-125	ferredoxin reductase	Rattus norvegicus	14-16
31232002-5	2019	In addition, RLM1 gene knockout affected the osmotic stress resistance, cell wall damage resistance, nitrogen starvation resistance and temperature tolerance of yeast strain.	Nitrogen	101-109	Rlm1p	Saccharomyces cerevisiae S288C	13-17
31718088-5	2019	By conducting bulk actin depolymerization assays and monitoring single-filament severing by total internal reflection fluorescence (TIRF) microscopy, we found that the N-terminal domains of both isoforms enhanced cofilin-mediated severing and depolymerization at similar rates.	Nitrogen	168-169	cofilin 1	Homo sapiens	213-220
32817462-9	2020	We propose that cumulative nitrations of Y190, Y317, and Y380 by reactive nitrogen species cause destabilization of CYP2B6, which may act synergistically with heme nitrosylation to target the enzyme for degradation.	Nitrogen	74-82	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	116-122
31718088-8	2019	Along with higher binding affinities of the higher-order oligomers to actin, this observation suggests that the mechanism of actin severing and depolymerization involves simultaneous or consequent and coordinated binding of more than one N-CAP domain to F-actin/cofilin complexes.	Nitrogen	238-239	cofilin 1	Homo sapiens	262-269
31406663-2	2019	This study details a viable in situ reconstruction of zinc-nitrogen coordinated cobalt-molybdenum disulfide from structure directing metal-organic framework (MOF) to constitute specific heteroatomic coordination and surface ligand functionalization.	Nitrogen	59-67	lysine acetyltransferase 8	Homo sapiens	133-162
32383652-9	2020	We also found that the NUE would decrease from 63% during 2010-2016 to 50% by 2050, whereas the total N surplus would increase from 13 kg N ha-1 yr-1 to 90 kg N ha-1 yr-1 by 2050.	Nitrogen	102-103	solute carrier family 9 member B1	Homo sapiens	138-149
31406663-4	2019	The zinc-nitrogen coordinated cobalt-molybdenum disulfide shows exceptional catalytic activity and stability toward the hydrogen evolution reaction with a low overpotential of 72.6 mV at -10 mA cm-2 and a small Tafel slope of 37.6 mV dec-1.	Nitrogen	9-17	deleted in esophageal cancer 1	Homo sapiens	234-239
31570524-3	2019	The role of an N-terminal multimerization domain in the supramolecular organization of MUC5B has been previously described, but less is known about its C-terminal dimerization domain.	Nitrogen	15-16	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	87-92
32510425-5	2020	The obvious spectra shift of FT-IR/XPS indicated that Lewis acid-base interaction was the main adsorption impetus; meanwhile hydrogen bonding interaction and pi-pi/n-pi (electron-donator-acceptor) EDA interaction should be included.	Nitrogen	164-166	ectodysplasin A	Homo sapiens	197-200
31387702-7	2019	This is the first muPAD whose working range covers almost the entire trigger value range (0.32-2.3 mg N L-1) for ammonia nitrogen in freshwater systems which makes it suitable as a field screening tool for ammonia in freshwaters.	Nitrogen	121-129	neuroligin 1	Homo sapiens	102-107
31720227-11	2019	Conclusions: Our studies illustrate that GLB1 deficiency is not purely a ganglioside accumulation disorder, but instead a broad oligosaccharidosis that include representatives of many beta-linked galactose containing glycans and glycoconjugates including glycolipids, N-linked glycans, and various O-linked glycans.	Nitrogen	268-269	galactosidase beta 1	Homo sapiens	41-45
30641224-3	2019	METHODS: N-glycomic profiles of native and neuraminidase-treated HDL and LDL were obtained using HILIC-UHPLC-FLD.	Nitrogen	9-10	neuraminidase 1	Homo sapiens	43-56
30954271-4	2019	Some pandemic pH1N1 strains resist neutralization by SP-A due to differences in the N-glycosylation of viral hemagglutinin (HA).	Nitrogen	17-18	surfactant protein A1	Homo sapiens	53-57
30892132-5	2019	The glycan modifications of PD-1 could be observed in three potential N-linked glycosylation sites, while no substantial influences were detected to the binding of toripalimab.	Nitrogen	70-71	programmed cell death 1	Homo sapiens	28-32
32783947-7	2020	Accordingly, NACHO-mediated effects on alpha7 assembly and channel function require N-glycosylation and calnexin chaperone activity.	Nitrogen	13-14	calnexin	Homo sapiens	104-112
30952089-6	2019	Glycosylation modifications of PD-1 could be observed in three of the four potential N-linked glycosylation sites.	Nitrogen	85-86	programmed cell death 1	Homo sapiens	31-35
31442740-4	2019	The results of the 3-year field experiments showed that integrated straw mulch (S) and nitrogen fertilizer (N) treatments enhanced the activities of soil urease, invertase, alkaline phosphatase, and catalase by >1.8, 2.1, 2.0 and 1.4 fold, respectively, compared with the control treatment.	Nitrogen	87-95	catalase-3	Glycine max	199-207
32126728-6	2020	BET surface area of 532 m2 g-1 was obtained for NiMoS2/Carbon catalysts from the nitrogen physisorption analysis.	Nitrogen	81-89	delta/notch like EGF repeat containing	Homo sapiens	0-3
31409699-0	2019	WRKY1 Mediates Transcriptional Regulation of Light and Nitrogen Signaling Pathways.	Nitrogen	55-63	zinc-dependent activator protein-1	Arabidopsis thaliana	0-5
31409699-3	2019	Here, we describe the functional role of the WRKY1 transcription factor in controlling genome-wide transcriptional reprogramming of Arabidopsis (Arabidopsis thaliana) leaves in response to individual and combined light and N signals.	Nitrogen	223-224	zinc-dependent activator protein-1	Arabidopsis thaliana	45-50
31409699-4	2019	This includes a cross-regulatory network consisting of 724 genes regulated by WRKY1 and involved in both N and light signaling pathways.	Nitrogen	105-106	zinc-dependent activator protein-1	Arabidopsis thaliana	78-83
31409699-5	2019	The loss of WRKY1 gene function has marked effects on the light and N response of genes involved in N uptake and assimilation (primary metabolism) as well as stress response pathways (secondary metabolism).	Nitrogen	68-69	zinc-dependent activator protein-1	Arabidopsis thaliana	12-17
31409699-5	2019	The loss of WRKY1 gene function has marked effects on the light and N response of genes involved in N uptake and assimilation (primary metabolism) as well as stress response pathways (secondary metabolism).	Nitrogen	100-101	zinc-dependent activator protein-1	Arabidopsis thaliana	12-17
31409699-6	2019	Our results at the transcriptome and at the metabolite analysis level support a model in which WRKY1 enables plants to activate genes involved in the recycling of cellular carbon resources when light is limiting but N is abundant and upregulate amino acid metabolism when both light and N are limiting.	Nitrogen	287-288	zinc-dependent activator protein-1	Arabidopsis thaliana	95-100
31409699-7	2019	In this potential energy conservation mechanism, WRKY1 integrates information about cellular N and light energy resources to trigger changes in plant metabolism.	Nitrogen	93-94	zinc-dependent activator protein-1	Arabidopsis thaliana	49-54
30920211-5	2019	N2O acts as an oxygen donor to replenish the PTA support and release N2 in the whole reaction process.	Nitrogen	0-2	pre T cell antigen receptor alpha	Homo sapiens	45-48
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	zinc fingers and homeoboxes 2	Homo sapiens	69-72
30246502-7	2019	N-glycosylation mutation of EpCAM led to decrease phosphorylation of Raf, ERK, and Akt, and inhibited the Ras/Raf/ERK and PI3K/Akt signaling pathways.	Nitrogen	0-1	zinc fingers and homeoboxes 2	Homo sapiens	110-113
32709014-10	2020	Genome-wide association studies, employing questionnaire-based evaluations of individual chronotypes, revealed loci near clock genes and in the regions containing RGS16 and ALG10B, a gene encoding an enzyme involved in protein N-glycosylation.	Nitrogen	227-228	regulator of G protein signaling 16	Homo sapiens	163-168
32404529-6	2020	Some ACE2 proteins even tolerate the loss or acquisition of N-glycosylation sites located near the S interface.	Nitrogen	60-61	angiotensin converting enzyme 2	Homo sapiens	5-9
30801094-4	2019	After the analysis of the molecular structure and simulation through the molecular docking model, we have found that hT1R1 is essentially a recognition receptor for the nitrogen signal in the body, and it may recognize the umami substance through its amino group.	Nitrogen	169-177	taste 1 receptor member 1	Homo sapiens	117-122
31685687-0	2019	WRKY1 Integrates Cellular Nitrogen and Light-Energy Resources in Arabidopsis thaliana.	Nitrogen	26-34	zinc-dependent activator protein-1	Arabidopsis thaliana	0-5
32404529-6	2020	Some ACE2 proteins even tolerate the loss or acquisition of N-glycosylation sites located near the S interface.	Nitrogen	60-61	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	0-1
31197859-7	2019	However, the impairment is not very significant and the peptide affinity may also be restored and improved if the N-substituted motif of derived peptiod ligands can effectively interact with the PxxP-binding site of TIM SH3 domain.	Nitrogen	114-115	Rho guanine nucleotide exchange factor 5	Homo sapiens	216-219
30745342-4	2019	Selective permeabilization, protease sensitivity and N-glycosylation tagging suggested that Far1 is able to assume two different membrane topologies, differing in the orientation of the short hydrophilic C-terminus towards the lumen or the cytosol, respectively.	Nitrogen	53-54	fatty acyl-CoA reductase 1	Homo sapiens	92-96
32699849-9	2020	Common nsp4 interactors include N -linked glycosylation machinery, unfolded protein response (UPR) associated proteins, and anti-viral innate immune signaling factors.	Nitrogen	32-33	serine protease 57	Homo sapiens	7-11
30828707-6	2019	Notably, the extra optical absorption caused by the positively-charged VH in KDP could be largely reduced by decreasing the defect concentration, whereas ADP exhibits defect-location dependence - the optical damage center of the VH in the NH4+ group could not be eliminated because of electron capture of its neighboring N atoms.	Nitrogen	0-1	WNK lysine deficient protein kinase 1	Homo sapiens	77-80
30880546-6	2019	Results suggested that hirudin could reduce the increased level of proteinuria, serum creatinine and urea nitrogen in IgAN models.	Nitrogen	106-114	IGAN1	Homo sapiens	118-122
32665328-7	2020	Among the genes potentially promoting successful transitions to major nodulation lineages, the nod and nif clusters for nodulation and nitrogen fixation, respectively, were repeatedly acquired during each transition; the fix, dct, and phb clusters involved in energy conservation under micro-oxic conditions were present in the nonnodulating ancestors; and the secretion systems were acquired in lineage-specific patterns.	Nitrogen	135-143	atrophin 1	Homo sapiens	70-73
31673804-3	2019	S1 consists of 863 amino acid residues with predicted molecular mass 91,029 Da and includes two N-terminal surface layer homology (SLH) domains, but most of its sequence shows no homology with proteins of known function.	Nitrogen	96-97	retinoschisin 1	Rattus norvegicus	0-2
31622882-2	2019	Here, we dissected the signals controlling phosphorylation and activity of the TORC1-effector kinase Npr1, involved in tuning the plasma membrane permeability to nitrogen sources.	Nitrogen	162-170	CREB regulated transcription coactivator 1	Homo sapiens	79-84
31641889-2	2019	Herein, a highly active electrocatalyst of nitrogen-doped porous carbon nanosheets coupled with Mo2C nanoparticles (Mo2C/NPC) was synthesized by a novel method with high BET surface area of 1380 m2 g-1 using KOH to activate carbon composite materials.	Nitrogen	43-51	delta/notch like EGF repeat containing	Homo sapiens	170-173
31623211-10	2019	In addition, the structure-activity relationship (SAR) of EI revealed that the "Arg1-Asn2-Hyp3" residues at the N-terminus conferred potency at the muscle-type nAChRs, and the deletion analogue  1-3 EI caused a total loss of activity at the alpha1beta1deltaepsilon nAChR.	Nitrogen	112-113	arginase, liver	Mus musculus	80-84
30930934-9	2019	Some of them could be related to certain important differences in metabolism previously reported by other authors such us DAL3 and ARO4, involved in nitrogen assimilation and amino acid biosynthesis.	Nitrogen	149-157	ureidoglycolate hydrolase	Saccharomyces cerevisiae S288C	122-126
30930934-9	2019	Some of them could be related to certain important differences in metabolism previously reported by other authors such us DAL3 and ARO4, involved in nitrogen assimilation and amino acid biosynthesis.	Nitrogen	149-157	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	131-135
30801086-3	2019	The layered compounds demonstrate a permanent porosity with a BET surface area of up to 688 m2 g-1 with the possibility of selective gas adsorption (CO2 over N2 and CH4).	Nitrogen	158-160	delta/notch like EGF repeat containing	Homo sapiens	62-65
32620165-3	2020	N-linked glycosylation of PD-L1 maintains its protein stability and interaction with its cognate receptor, programmed cell death protein 1 (PD-1), and this in turn promotes evasion of T-cell immunity.	Nitrogen	0-1	programmed cell death 1	Homo sapiens	107-138
30502532-0	2019	Interfacial engineering of 0D/2D SnS2 heterostructure onto nitrogen-doped graphene for boosted lithium storage capability.	Nitrogen	59-67	sodium voltage-gated channel alpha subunit 11	Homo sapiens	33-37
30502532-3	2019	Interestingly, the SnS2 particles formed show two totally different morphologies including ultrasmall nanoparticles about 5 nm and ultrathin nanosheets, and they are strongly coupled with nitrogen-doped graphene, giving rise to a unique 0D/2D heterostructure.	Nitrogen	188-196	sodium voltage-gated channel alpha subunit 11	Homo sapiens	19-23
30502532-6	2019	Such a unique hierarchical nanostructure and the strong interfacial interaction between 0D/2D SnS2 and nitrogen-doped graphene highlight the lithium storage performance of SnS2/NG.	Nitrogen	103-111	sodium voltage-gated channel alpha subunit 11	Homo sapiens	172-176
31618357-7	2019	B-type natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) have been noted to be associated with left ventricular systolic and diastolic and right ventricular dysfunction in patients with septic cardiomyopathy.	Nitrogen	29-30	natriuretic peptide B	Homo sapiens	0-26
32620165-3	2020	N-linked glycosylation of PD-L1 maintains its protein stability and interaction with its cognate receptor, programmed cell death protein 1 (PD-1), and this in turn promotes evasion of T-cell immunity.	Nitrogen	0-1	programmed cell death 1	Homo sapiens	140-144
31637240-11	2019	Our study demonstrated direct binding of IFT complex B proteins IFT52 and IFT57 to the N-terminal ankyrin repeats and the central domain of SANS.	Nitrogen	87-88	intraflagellar transport 57	Homo sapiens	74-79
30785733-2	2019	Recently, the Sun group has disclosed a family of highly active water oxidation catalysts, [Ru(bda)(L)2] (bda2- = 2,2"-bipyridine-6,6"-dicarboxylate; L = N-containing ligands).	Nitrogen	154-155	bone morphogenetic protein 2	Homo sapiens	106-110
32620165-6	2020	Notably, the removal of N-linked glycosylation enhances PD-L1 detection in a variety of bioassays and more accurately predicts the therapeutic efficacy of PD-1/PD-L1 inhibitors, suggesting an important clinical implication of PD-L1 N-linked glycosylation.	Nitrogen	0-1	programmed cell death 1	Homo sapiens	155-159
32017295-3	2020	The structures of the N-terminus and C-terminus of CENP-I homologs in complex with CENP-H/K have been reported, respectively.	Nitrogen	22-23	centromere protein H	Homo sapiens	83-89
30801341-2	2019	Importantly, many of these ECM molecules display N- and O-linked glycan residues and are considered as potential targets for galectin-1 (Gal-1) and galectin-3 (Gal-3).	Nitrogen	49-50	galectin 3	Homo sapiens	148-158
30801341-2	2019	Importantly, many of these ECM molecules display N- and O-linked glycan residues and are considered as potential targets for galectin-1 (Gal-1) and galectin-3 (Gal-3).	Nitrogen	49-50	galectin 3	Homo sapiens	160-165
30683917-12	2019	N-glycosylation of PAR2 at Asn30 reduces the efficacy, but enhances selectivity of the Furin cleavage.	Nitrogen	0-1	F2R like trypsin receptor 1	Homo sapiens	19-23
30683917-12	2019	N-glycosylation of PAR2 at Asn30 reduces the efficacy, but enhances selectivity of the Furin cleavage.	Nitrogen	0-1	furin, paired basic amino acid cleaving enzyme	Homo sapiens	87-92
32001344-0	2020	The Synthesis and Secretion of Versican Isoform V3 by Mammalian Cells: A Role for N-linked Glycosylation.	Nitrogen	82-83	versican	Homo sapiens	31-39
31418149-2	2019	N2 adsorption and desorption isotherms of AC showed a high BET surface area of 2434 m2 g-1 and a total volume of pores (VT) of 2.0447 m3 g-1 for AC.	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	59-62
30387162-7	2019	TLR2-deficient mice exacerbated renal injury in cisplatin-induced AKI, with higher serum creatinine and blood urea nitrogen, more severe morphological injury compared with that of wild-type mice.	Nitrogen	115-123	toll-like receptor 2	Mus musculus	0-4
32974605-11	2020	This study therefore, predicts that there is a cellular interchange between N-linked glycosylation properties of the human LAMP1 and LASV glycoprotein, and sialylation functions of ST3GAL4 in LASV infectivity.	Nitrogen	76-77	lysosomal associated membrane protein 1	Homo sapiens	123-128
30675762-5	2019	More significantly, the formation of polypyrrole-derived N/S dual-doped carbon is synergistically coupled with the ZnS/SnS2 to create a unique and robust architecture, further strengthening the interconnect function at the heterointerface, which improves electric/ion transfer and mitigates the volume variation during the long-term cycling process.	Nitrogen	57-58	sodium voltage-gated channel alpha subunit 11	Homo sapiens	119-123
31313105-11	2019	Gene Ontology (GO) analysis was used to determine the biological function of these targets and revealed that some miRNAs, such as miR169, miR1214, miR2199, miR398, miR408 and miR827 might be involved in nitrogen metabolism regulation.	Nitrogen	203-211	MIR827	Zea mays	175-181
31572374-0	2019	Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7.	Nitrogen	41-42	C-C motif chemokine ligand 21	Homo sapiens	20-25
30477902-4	2019	The effects of inoculation and different water regimes were also assessed for the maize rhizospheric and surface soil communities by MiSeq community sequencing combined with qPCR of functional genes and transcripts (nifH and amoA) related to nitrogen cycling.	Nitrogen	242-250	nifH	Pseudomonas stutzeri A1501	216-220
31572374-0	2019	Biased Signaling of CCL21 and CCL19 Does Not Rely on N-Terminal Differences, but Markedly on the Chemokine Core Domains and Extracellular Loop 2 of CCR7.	Nitrogen	41-42	C-C motif chemokine ligand 19	Homo sapiens	30-35
32015811-2	2019	Based on molecular dynamics simulations, N-terminally modified GLP-1 analogues with a ureido residue replacement at position 2 were synthesized and showed preservation of agonist activity while exhibiting a substantial increase in stability.	Nitrogen	41-42	glucagon like peptide 1 receptor	Homo sapiens	63-68
31319149-1	2019	Magnesium stearate is an extremely common pharmaceutical excipient and the measurement of BET surface area via nitrogen adsorption is undertaken during pharmaceutical formulation and manufacture.	Nitrogen	111-119	delta/notch like EGF repeat containing	Homo sapiens	90-93
30508577-5	2019	In adults, this increased generation of reactive oxygen and nitrogen species (RONS) activate redox-sensitive transcription factors such as nuclear factor kappaB (NFkappaB), activator protein-1 (AP1) and heat shock factor 1 (HSF1), resulting in increases in cytoprotective proteins such as the superoxide dismutases, catalase and heat shock proteins that prevent oxidative damage to tissues and facilitate remodelling and proteostasis in both an intra- and inter-cellular manner.	Nitrogen	60-68	heat shock transcription factor 1	Homo sapiens	203-222
30508577-5	2019	In adults, this increased generation of reactive oxygen and nitrogen species (RONS) activate redox-sensitive transcription factors such as nuclear factor kappaB (NFkappaB), activator protein-1 (AP1) and heat shock factor 1 (HSF1), resulting in increases in cytoprotective proteins such as the superoxide dismutases, catalase and heat shock proteins that prevent oxidative damage to tissues and facilitate remodelling and proteostasis in both an intra- and inter-cellular manner.	Nitrogen	60-68	heat shock transcription factor 1	Homo sapiens	224-228
30728400-0	2019	The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1.	Nitrogen	34-42	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	103-107
30728400-0	2019	The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1.	Nitrogen	34-42	CREB regulated transcription coactivator 1	Mus musculus	112-118
32420740-6	2020	The calculated results rationalize the experimentally observed enantio- and regioselectivities, and reveal that enantioselectivity of the reaction originates from the hydrogen bond interaction between TRIP and the N-H group of the carbon-centered radical, and the regioselectivity arises from the electron-withdrawing inductive effect from protonated N-atom and intramolecular hydrogen bond interaction between the acetylamino group and the protonated pyridine ring.	Nitrogen	214-215	TRAF interacting protein	Homo sapiens	201-205
30728400-11	2019	The ability of cells to utilise ammonia as a nitrogen source is intricately linked to AMPK, mTORC1 and GDH.	Nitrogen	45-53	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	86-90
30728400-11	2019	The ability of cells to utilise ammonia as a nitrogen source is intricately linked to AMPK, mTORC1 and GDH.	Nitrogen	45-53	CREB regulated transcription coactivator 1	Mus musculus	92-98
31598403-4	2019	To enhance the efficacy of immunotherapy, in this report, we designed an endoplasmic reticulum (ER)-targeting sequence (adenovirus E3/19K protein) at the N-terminus of TAL6 to facilitate MHC class I antigen presentation to CD8+ T cells.	Nitrogen	154-155	transmembrane 4 L six family member 1	Homo sapiens	168-172
32577017-3	2020	To determine the functions of Dkk3 in the mouse adrenal gland, we first identified that the mouse Dkk3 protein is N-glycosylated in the adrenal gland as well as in the brain.	Nitrogen	114-115	dickkopf WNT signaling pathway inhibitor 3	Mus musculus	98-102
31186110-0	2019	Novel glycosylated human interferon alpha 2b expressed in glycoengineered Pichia pastoris and its biological activity: N-linked glycoengineering approach.	Nitrogen	0-1	interferon alpha 2	Homo sapiens	25-44
30778361-7	2019	Short statement: The improvement in N recycling during leaf senescence in a genotype of Brassica napus L. characterized by a high nitrogen remobilization efficiency is related to a high phytohormonal ratio ([salicylic acid] + [abscisic acid])/([cytokinins]) that promotes leaf senescence and is correlated with an increase or the induction of specific serine and cysteine protease activities.	Nitrogen	36-37	thiol protease aleurain	Brassica napus	363-380
32168410-1	2020	BACKGROUND: The protective/inhibitory B subunits of coagulation factor XIII (FXIII-B) is a ~80 kDa glycoprotein containing two N-glycosylation sites.	Nitrogen	8-9	coagulation factor XIII B chain	Homo sapiens	77-84
30445264-5	2019	Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions.	Nitrogen	100-101	carbonic anhydrase 9	Homo sapiens	45-50
30445264-5	2019	Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions.	Nitrogen	100-101	PC4 and SFRS1 interacting protein 1	Homo sapiens	204-207
30445264-5	2019	Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions.	Nitrogen	100-101	phospholipase B domain containing 2	Homo sapiens	209-212
32317363-9	2020	Transcriptional analyses of cepr1 bolts showed alterations in the expression levels of several genes of the CEP-CEPR1 and nitrogen homeostasis pathways.	Nitrogen	122-130	Leucine-rich repeat transmembrane protein kinase family protein	Arabidopsis thaliana	28-33
30445264-5	2019	Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions.	Nitrogen	116-117	carbonic anhydrase 9	Homo sapiens	45-50
32317363-10	2020	This transcriptional profile was consistent with cepr1 bolts being nitrogen-deficient, and with a reproductive tissue-specific function for CEP-CEPR1 signalling.	Nitrogen	67-75	Leucine-rich repeat transmembrane protein kinase family protein	Arabidopsis thaliana	49-54
31474717-6	2019	Protein expression of spinal N(G),N(G)-dimethylarginine dimethylaminohydralase 1 (DDAH1), a key enzyme involved in the metabolism of the endogenous NOS, increased on day 1 after BCAO, but not on day 3.	Nitrogen	29-30	dimethylarginine dimethylaminohydrolase 1	Mus musculus	82-87
31474717-6	2019	Protein expression of spinal N(G),N(G)-dimethylarginine dimethylaminohydralase 1 (DDAH1), a key enzyme involved in the metabolism of the endogenous NOS, increased on day 1 after BCAO, but not on day 3.	Nitrogen	34-35	dimethylarginine dimethylaminohydrolase 1	Mus musculus	82-87
32317363-11	2020	The results reveal a local role for CEPR1 in the maternal reproductive tissue in determining seed size and yield, likely via the control of nitrogen delivery to the reproductive sinks.	Nitrogen	140-148	Leucine-rich repeat transmembrane protein kinase family protein	Arabidopsis thaliana	36-41
32528729-5	2020	In mouse models, tubule-specific deletion of Rictor had higher blood urea nitrogen level, severe morphological injury as well as more inflammatory cells accumulation compared with those in their littermate controls.	Nitrogen	74-82	RPTOR independent companion of MTOR, complex 2	Mus musculus	45-51
30394304-4	2019	N-acetyl-beta-D-glucosaminidase was detected with high sensitivity and specificity at the early stage of renal injury (Area under the ROC cure (AUC) = 0.929, 95%CI: 0.722-0.995, P &lt; 0.05 vs. serum creatinine and blood urea nitrogen).	Nitrogen	226-234	O-GlcNAcase	Homo sapiens	0-31
30583600-6	2018	Inflammation was ameliorated by suppression of Arg-1 to adjust the disturbed metabolic pathways induced by aPM2.5, such as arginine and nitrogen metabolism and aminoacyl-tRNA biosynthesis, for 11 weeks.	Nitrogen	136-144	arginase 1	Rattus norvegicus	47-52
32196953-4	2020	Moreover, the optimized N,S co-doped MOF exhibits the lowest overpotential of 254 mV at 10 mA cm-2 on a glass carbon electrode and a small Tafel slope of 50 mV dec-1, especially, this catalyst also possesses long-term electrochemical durability for at least 16 hrs.	Nitrogen	24-25	deleted in esophageal cancer 1	Homo sapiens	160-165
30550553-3	2018	We have addressed the mechanisms that might regulate the association between GLTP and the VAP proteins by studying the capacity of GLTP to recognize different N-linked acyl chain species of glucosylceramide.	Nitrogen	159-160	glycolipid transfer protein	Homo sapiens	131-135
30550553-4	2018	We used surface plasmon resonance and a lipid transfer competition assay to show that GLTP prefers shorter N-linked fully saturated acyl chain glucosylceramides, such as C8, C12, and C16, whereas long C18, C20, and C24-glucosylceramides are all bound more weakly and transported more slowly than their shorter counterparts.	Nitrogen	107-108	glycolipid transfer protein	Homo sapiens	86-90
32030866-2	2020	Here, we design a three-in-one surface treatment via the pyrolysis of urea to improve the voltage and capacity stability of Li1.2Mn0.6Ni0.2O2 (LMNO), by which oxygen vacancy, spinel phase integration and N-doped carbon nanolayer are synchronously built on the surface of LMNO microspheres.	Nitrogen	134-135	transglutaminase 1	Homo sapiens	124-127
30309983-2	2018	The Gag protein of avian sarcoma virus (ASV) lacks the N-myristoylation signal but contains structural domains having functions similar to those of HIV-1 Gag.	Nitrogen	55-56	Pr55(Gag)	Human immunodeficiency virus 1	4-7
32050057-8	2020	XRD, XPS and electrochemical measurement confirm the reactivity of carbonyl group and N-heterocycle toward Li+ and PF6- respectively.	Nitrogen	86-87	sperm associated antigen 17	Homo sapiens	115-118
30628379-12	2018	(2) The total flux of nitrogen deposition is 43.14 kg hm-2 in the Shixia Catchment; the wet and dry deposition flux account for 39.85% and 60.15%, respectively.	Nitrogen	22-30	cholinergic receptor muscarinic 2	Homo sapiens	54-58
32054419-5	2020	Under nitrogen-starvation conditions, the Spt4-Spt5 complex derepresses ATG8 and ATG41 expression and upregulates bulk autophagy activity.	Nitrogen	6-14	SPT5 homolog, DSIF elongation factor subunit	Homo sapiens	47-51
30656284-2	2019	The majority of APTT reagents also accurately recover the activity of the extended half-life molecule N-glycoPEGylated FVIII (N8-GP; turoctocog alfa pegol), while a few silica-based reagents give a low recovery.	Nitrogen	102-103	coagulation factor VIII	Homo sapiens	119-124
30584598-6	2018	Conclusion: Our study suggests that brain somatic mutations in SLC35A2 cause intractable focal epilepsy with NLFE or mMCD via aberrant N-glycosylation in the affected brain.	Nitrogen	109-110	solute carrier family 35 member A2	Homo sapiens	63-70
32160104-0	2020	Ubiquitin-proteasome mediated cyclin C degradation promotes cell survival following nitrogen starvation.	Nitrogen	84-92	ubiquitin	Saccharomyces cerevisiae S288C	0-9
30733794-2	2018	Biological nitrogen fixation in legumes is a functional combination of nodulation by nod genes and regulation by nif, fix genes.	Nitrogen	11-19	CTD small phosphatase like	Gallus gallus	113-116
30733794-4	2018	An attempt has been made to understand the structural characteristics and variations of nif genes that may reveal the factors influencing the nitrogen fixation.	Nitrogen	142-150	CTD small phosphatase like	Gallus gallus	88-91
30733794-6	2018	Literature shows that the homology modeling of nif A protein have not been explored yet which insisted the immediate development for better understanding of nif A structure and its influence on biological nitrogen fixation.	Nitrogen	205-213	CTD small phosphatase like	Gallus gallus	47-50
30733794-6	2018	Literature shows that the homology modeling of nif A protein have not been explored yet which insisted the immediate development for better understanding of nif A structure and its influence on biological nitrogen fixation.	Nitrogen	205-213	CTD small phosphatase like	Gallus gallus	157-160
32281057-6	2020	Computer structural modeling suggests the deleted amino acid residues are located near the biotinidase active site and disrupt the special conformations which are critical for the enzyme activity, and also N-glycosylation.	Nitrogen	206-207	biotinidase	Homo sapiens	91-102
30385225-3	2018	Here, we report the synthesis and biological evaluation of a new series of HNE inhibitors with a pyrrolo[2,3-b]pyridine scaffold, which is an isomer of our previously reported indazoles, in order to assess how a shift of the nitrogen from position 2 to position 7 influences activity.	Nitrogen	225-233	elastase, neutrophil expressed	Homo sapiens	75-78
31901180-0	2020	Distinct non-coding RNAs confer root-dependent sense transgene-induced posttranscriptional gene silencing and nitrogen-dependent posttranscriptional regulation to AtAMT1;1 transcript in Arabidopsis roots.	Nitrogen	110-118	ammonium transporter 1;1	Arabidopsis thaliana	163-171
30002126-0	2018	N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice.	Nitrogen	0-1	coagulation factor VIII	Mus musculus	73-84
30002126-11	2018	Collectively, our data suggest that factor VIII produced in baby hamster kidney cells is more immunogenic than that produced in Chinese hamster ovary cells, and that incomplete occupancy of N-linked glycosylation sites leads to the formation of immunoglobulin M- and immunoglobulin G-factor VIII immune complexes that contribute to the enhanced clearance and immunogenicity in these mouse models of hemophilia A.	Nitrogen	190-191	coagulation factor VIII	Mus musculus	36-47
30002126-11	2018	Collectively, our data suggest that factor VIII produced in baby hamster kidney cells is more immunogenic than that produced in Chinese hamster ovary cells, and that incomplete occupancy of N-linked glycosylation sites leads to the formation of immunoglobulin M- and immunoglobulin G-factor VIII immune complexes that contribute to the enhanced clearance and immunogenicity in these mouse models of hemophilia A.	Nitrogen	190-191	coagulation factor VIII	Mus musculus	284-295
30320513-1	2018	Compost is organic material that has been degraded into a nutrient-stabilized humus-like substance through intense microbial activity, which can provide essential plant nutrients (nitrogen, phosphorus) to aid in the growth of fruits and vegetables.	Nitrogen	180-188	activation induced cytidine deaminase	Homo sapiens	205-208
30158294-8	2018	Our results demonstrate that N294 is the major site of N-glycosylation in SERINC5.	Nitrogen	29-30	serine incorporator 5	Homo sapiens	74-81
30158294-9	2018	Although N-glycosylation was required neither for restrictive activity nor for sensitivity to Nef per se, we observed a decrease in the steady-state expression of glycosylation-deficient SERINC5 (the N294A mutant) compared to the wild-type protein.	Nitrogen	9-10	serine incorporator 5	Homo sapiens	187-194
29945033-1	2018	In this work, we systematically investigated the persulfate (PS) activation potential of a series of nitrogen doped carbonaceous materials for the degradation of 2,4,4"-trihydroxybenzophenone (2,4,4"-HBP), an additive in polyvinyl acetate films and personal care products.	Nitrogen	101-109	heme binding protein 1	Homo sapiens	200-203
29945033-6	2018	To the best of our knowledge, this report is the first to describe the transformation mechanism of 2,4,4"-HBP in nitrogen doped carbonaceous materials catalyzed PS system.	Nitrogen	113-121	heme binding protein 1	Homo sapiens	106-109
30012463-5	2018	Among the potential corresponding target mRNAs for the selected mature miRNAs, seven cell growth-related target genes (e2f2, akt2, mtor, bcl-2, bim, p38alpha, and bmf) and five N-glycosylation-related target genes (neu1, b4galt3, gale, man1b1 and mgat4a) were selected by considering the effectiveness of NaBu on rCHO cell culture.	Nitrogen	43-44	neuraminidase 1	Rattus norvegicus	215-219
30229595-3	2018	(2)Total nitrogen deposition in the growing season (wet+dry particulate deposition) and non-growing season (bulk deposition) were 11.42 kg hm-2 and 1.51 kg hm-2respectively, which account for 88.3% and 11.7% of the total nitrogen deposition respectively.	Nitrogen	9-17	cholinergic receptor muscarinic 2	Homo sapiens	139-149
30229595-4	2018	(3)Total wet nitrogen deposition during the growing season was 9.28 kg hm-2, contributing to 81.3% of the total nitrogen deposition in the growing season, and was positively correlated with precipitation (R2=0.87, P&lt;0.001); total dry particulate nitrogen deposition in the growing season was 2.14 kg hm-2, which was 18.7% of the total nitrogen deposition in growing season.	Nitrogen	13-21	cholinergic receptor muscarinic 2	Homo sapiens	71-75
30349486-1	2018	Background: Nicotinamide N-methyltransferase (NNMT) is an enzyme that catalyzes N-methylation of pyridine-containing compounds.	Nitrogen	12-13	nicotinamide N-methyltransferase	Homo sapiens	46-50
30092656-1	2018	The plant GATA family is one of the most important transcription factors involved in light-responsive development, nitrogen metabolism, phytohormone signaling, and source/sink balance.	Nitrogen	115-123	glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial	Vitis vinifera	10-14
31949578-7	2018	Compared with the control (normal lipid) group, the dyslipidemia group with IgAN had higher blood uric acid, serum creatinine, blood urea nitrogen and urinary protein quantity, higher proportions of mesangial cell proliferation and renal tubular atrophy/interstitial fibrosis (IFTA), and a lower estimated glomerular filtration rate and serum albumin.	Nitrogen	138-146	IGAN1	Homo sapiens	76-80
30113821-5	2018	In the NL2+ species, a nitrogen atom with a formal positive charge accepts electron density from electron-donating ligands.	Nitrogen	23-31	membrane metalloendopeptidase like 1	Homo sapiens	7-10
30275691-0	2018	The role of plasma N-terminal brain natriuretic pro-peptide in diagnosing elderly patients with acute exacerbation of COPD concurrent with left heart failure.	Nitrogen	19-20	COPD	Homo sapiens	118-122
30209257-0	2018	MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS. Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions.	Nitrogen	97-98	immunoglobulin heavy variable V1-62	Mus musculus	1-4
30209257-0	2018	MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS. Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions.	Nitrogen	97-98	immunoglobulin heavy variable V1-62	Mus musculus	15-18
30209257-0	2018	MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS. Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions.	Nitrogen	97-98	immunoglobulin heavy variable V1-62	Mus musculus	15-18
30209257-0	2018	MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS. Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions.	Nitrogen	166-167	immunoglobulin heavy variable V1-62	Mus musculus	15-18
30209257-0	2018	MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS. Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions.	Nitrogen	166-167	immunoglobulin heavy variable V1-62	Mus musculus	143-159
30209257-0	2018	MIgGGly (mouse IgG glycosylation analysis) - a high-throughput method for studying Fc-linked IgG N-glycosylation in mice with nanoUPLC-ESI-MS. Immunoglobulin G (IgG) N-glycosylation is crucial for its effector functions.	Nitrogen	166-167	immunoglobulin heavy variable V1-62	Mus musculus	15-18
30209257-7	2018	We have applied our method to a sample set of 3 inbred strains: BALB/c, C57BL/6 and C3H and observed differences in subclass-specific and strain-specific N-glycosylation of IgG, suggesting a significant genetic component in the regulation of Fc-linked IgG N-glycosylation.	Nitrogen	154-155	immunoglobulin heavy variable V1-62	Mus musculus	173-176
30209257-7	2018	We have applied our method to a sample set of 3 inbred strains: BALB/c, C57BL/6 and C3H and observed differences in subclass-specific and strain-specific N-glycosylation of IgG, suggesting a significant genetic component in the regulation of Fc-linked IgG N-glycosylation.	Nitrogen	256-257	immunoglobulin heavy variable V1-62	Mus musculus	173-176
30004225-1	2018	We report the first purely chemical method for the resolution of C, N-unprotected racemic alpha-substituted beta-amino acids (beta2-AAs) using thermodynamically stable and recyclable chiral proline-derived ligands.	Nitrogen	68-69	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	126-131
29897653-1	2018	Two new calcium nitridomanganates, Ca12 [Mn19 N23 ] (P3, a=11.81341(3) A, c=5.58975(2) A, Z=1) and Ca133 [Mn216 N260 ] (P3  , a=39.477(1) A, c=5.5974(2) A, Z=1), were obtained by a gas-solid reaction of Ca3 N2 and Mn with N2 at 1273 K and 1223 K, respectively.	Nitrogen	46-48	carbonic anhydrase 12	Homo sapiens	35-39
29672923-3	2018	First, we demonstrate that 1,1"-beta-D-glucopyranosyl-3,3"-bis(5-bromoindolyl)-octyl methane (NGD16), an N-glycosylated derivative of medicinally important phytochemical 3,3"-diindolylmethane (DIM) abrogates EMT by inducing pro-apoptotic protein Par-4.	Nitrogen	94-95	PRKC, apoptosis, WT1, regulator	Mus musculus	246-251
30041084-10	2018	Thirdly, the abundance of PPDK and PEPCK is often associated with the metabolism of certain nitrogenous compounds and can be dramatically altered by factors related to nitrogen metabolism.	Nitrogen	92-100	pyruvate, phosphate dikinase 1, chloroplastic	Zea mays	26-30
30041084-10	2018	Thirdly, the abundance of PPDK and PEPCK is often associated with the metabolism of certain nitrogenous compounds and can be dramatically altered by factors related to nitrogen metabolism.	Nitrogen	92-100	phosphoenolpyruvate carboxykinase (ATP)	Zea mays	35-40
31466258-3	2019	TGA showed that carbon fillers improved the resistance to thermal and thermo-oxidative degradation under both air and nitrogen atmospheres.	Nitrogen	118-126	T-box transcription factor 1	Homo sapiens	0-3
31462009-10	2019	According to nonlinear regression, the concentrations of serum syndecan-1 were significantly related to age (p = 0.016), aspartic aminotransferase concentration (AST, p = 0.020), blood urea nitrogen concentration (BUN, p = 0.013), triglyceride concentration (p &lt; 0.001), and hematocrit (p = 0.006).	Nitrogen	190-198	syndecan 1	Homo sapiens	63-73
31327656-0	2019	Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.	Nitrogen	11-12	programmed cell death 1	Homo sapiens	77-81
30905597-7	2019	Moreover, structural characterization of endogenous ALCAM N-glycosylation showed abundant permissive structures for Gal-8 binding.	Nitrogen	58-59	activated leukocyte cell adhesion molecule	Homo sapiens	52-57
31185295-5	2019	In this study, we tested the hypothesis that N-glycans in the FVII protease domain mediate calnexin-assisted protein folding and that naturally occurring F7 mutations abolishing N-glycosylation impair FVII secretion.	Nitrogen	45-46	calnexin	Homo sapiens	91-99
31185295-9	2019	Elimination of N-glycosylation at N360 impaired calnexin-assisted FVII folding and secretion.	Nitrogen	15-16	calnexin	Homo sapiens	48-56
31362455-5	2019	Forty fungal isolates were screened for ODC production, twenty fungal isolates have the higher potency to grow on L-ornithine as sole nitrogen source.	Nitrogen	134-142	ornithine decarboxylase 1	Homo sapiens	40-43
31302781-2	2019	The surface of a glassy carbon electrode (GCE) was first modified with nitrogen-doped graphene and then gold nanoparticles and graphene quantum dots electrodeposited on it to obtain an architecture of type GQD/AuNP/NG/GCE.	Nitrogen	71-79	glycine cleavage system protein H	Homo sapiens	42-45
31608127-10	2019	Two different proteoforms of calmodulin, with either only N-terminal acetylation or both N-terminal acetylation and K115 trimethylation, were identified in the zebrafish brain sample.	Nitrogen	58-59	calmodulin 3b (phosphorylase kinase, delta)	Danio rerio	29-39
31608127-10	2019	Two different proteoforms of calmodulin, with either only N-terminal acetylation or both N-terminal acetylation and K115 trimethylation, were identified in the zebrafish brain sample.	Nitrogen	89-90	calmodulin 3b (phosphorylase kinase, delta)	Danio rerio	29-39
31249587-10	2019	In addition, nitrogen deposition and phosphorus inputs may also alter the status of some alien species.	Nitrogen	13-21	COP9 signalosome subunit 2	Homo sapiens	89-94
31244828-4	2019	MOG has one known N-glycosylation site at N31 located in the BC loop linking two beta-sheets.	Nitrogen	18-19	myelin oligodendrocyte glycoprotein	Homo sapiens	0-3
31120459-1	2019	Disclosed herein is a rhodium(iii)-catalyzed novel one-step back-to-back double rollover annulation on pyridine and pyrazine backbones leading to a structurally and optoelectronically diverse class of nicely decorated multi-ring-fused, extensively pi-conjugated, N-enriched PAH molecules by virtue of orchestrated quadruple C-H activation events.	Nitrogen	263-264	phenylalanine hydroxylase	Homo sapiens	274-277
30976803-6	2019	Finally, we discover indications of a novel functional role for three TFs; Gcn4, Ert1 and Sut1 during nitrogen limited aerobic fermentation.	Nitrogen	102-110	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	75-79
30976803-6	2019	Finally, we discover indications of a novel functional role for three TFs; Gcn4, Ert1 and Sut1 during nitrogen limited aerobic fermentation.	Nitrogen	102-110	Ert1p	Saccharomyces cerevisiae S288C	81-85
31019249-0	2019	Author Correction: Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants.	Nitrogen	59-67	immunoglobulin superfamily member 9	Homo sapiens	27-31
30859215-9	2019	HMGB1 knockdown by siRNA also reduced both ROS and reactive nitrogen species (RNS) and IL-6 levels but not TNF-alpha.	Nitrogen	60-68	high mobility group box 1	Mus musculus	0-5
30027200-2	2018	The Emed values vary from 0.42 to 1.07 V vs. NHE depending on the number of nitrogen atoms and the presence of tert-butyl substituents on the ligand.	Nitrogen	76-84	solute carrier family 9 member C1	Homo sapiens	45-48
30072439-5	2018	In cwh43 mutants, comprehensive metabolome analysis demonstrated dramatic changes in marker metabolites that altered under low glucose and/or nitrogen starvation, although cwh43 cells apparently consumed glucose in the culture medium.	Nitrogen	142-150	Cwh43p	Saccharomyces cerevisiae S288C	3-8
30225018-4	2018	A satisfactory performance of the Si@N, O-doped carbon (Si@CNO) anode is gained at 25 and 55 C. The Si@CNO anode shows stable cycling performance (capacity retention of 70.0% over 100 cycles at 25 C and 60.3% over 90 cycles at 55 C with a current density of 500 mA g-1) and a superior rate capacity of 864.1 mA h g-1 at 1000 mA g-1 (25 C).	Nitrogen	37-38	biogenesis of lysosomal organelles complex 1 subunit 4	Homo sapiens	59-62
30225018-4	2018	A satisfactory performance of the Si@N, O-doped carbon (Si@CNO) anode is gained at 25 and 55 C. The Si@CNO anode shows stable cycling performance (capacity retention of 70.0% over 100 cycles at 25 C and 60.3% over 90 cycles at 55 C with a current density of 500 mA g-1) and a superior rate capacity of 864.1 mA h g-1 at 1000 mA g-1 (25 C).	Nitrogen	37-38	biogenesis of lysosomal organelles complex 1 subunit 4	Homo sapiens	103-106
31901180-1	2020	High-affinity ammonium uptake in roots mediate by AMT1-type ammonium transporters, which are tightly controlled at multiple regulatory levels for adapting various nitrogen availability.	Nitrogen	163-171	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	50-54
30072439-2	2018	Here, we report characterizations of fission yeast temperature-sensitive (ts) mutants of the evolutionarily conserved transmembrane protein Cwh43, and explore its relevance to utilization of glucose, nitrogen source and lipids.	Nitrogen	200-208	Cwh43p	Saccharomyces cerevisiae S288C	140-145
30072439-4	2018	We found that cwh43 mutants failed to divide in low glucose and lost viability during quiescence under nitrogen starvation.	Nitrogen	103-111	Cwh43p	Saccharomyces cerevisiae S288C	14-19
31367321-6	2019	Detailed analysis by DFT of the reaction of [(BDI)Mg{pinB(n-Bu)Bpin}] with PhN[double bond, length as m-dash]CHPh indicated that B-N bond formation is initiated by attack of the imine nitrogen at the three-coordinate boron atom of the diboranate anion rather than the more crowded magnesium centre.	Nitrogen	184-192	carbamoyl-phosphate synthase 1	Homo sapiens	75-78
30072439-8	2018	Thus, Cwh43 affects utilization of glucose and nitrogen sources, as well as storage lipid metabolism.	Nitrogen	47-55	Cwh43p	Saccharomyces cerevisiae S288C	6-11
31901180-2	2020	For Arabidopsis AtAMT1;1 gene, besides the transcriptional and posttranslational controls, an organ- and N-dependent posttranscriptional regulation was suggested as an additional regulatory step for fine-tuning ammonium uptake, but the underlying mechanisms remain to be elucidated.	Nitrogen	105-106	ammonium transporter 1;1	Arabidopsis thaliana	16-24
31901180-6	2020	In roots of these lines, however, the steady-state transcript levels of AtAMT1;1 still significantly decreased under conditions of N-sufficiency compared to N-deficiency, confirming a N-dependent posttranscriptional regulatory manner.	Nitrogen	131-132	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	72-78
31901180-6	2020	In roots of these lines, however, the steady-state transcript levels of AtAMT1;1 still significantly decreased under conditions of N-sufficiency compared to N-deficiency, confirming a N-dependent posttranscriptional regulatory manner.	Nitrogen	157-158	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	72-78
31142080-16	2019	(4) The expressions of LOX-1 mRNA and protein were lower in respective PCSK9 protein plus TAK-242, PDTC, NS-398 or DPI group than in PCSK9 protein alone (all P&lt;0.05).	Nitrogen	105-107	oxidized low density lipoprotein receptor 1	Homo sapiens	23-28
31901180-7	2020	A crucial role of 207 bp 3"-end sequence of AtAMT1;1 was further demonstrated by N-dependent accumulation of chimeric-AtAMT1;1 transcript in T-DNA insertion lines and of GFP-tagged chimeric-AtAMT1;1 transcript in transgenic lines.	Nitrogen	81-82	ammonium transporter 1;1	Arabidopsis thaliana	44-52
29945795-3	2018	Selective JAK1/2 inhibitor, ruxolitinib (3), and pan-HDAC inhibitor vorinostat (4) were linked together by a single nitrogen atom to create a new series of compounds with very potent JAK2 and HDAC6 inhibition with selectivity against HDAC1.	Nitrogen	116-124	Janus kinase 2	Homo sapiens	183-187
31901180-7	2020	A crucial role of 207 bp 3"-end sequence of AtAMT1;1 was further demonstrated by N-dependent accumulation of chimeric-AtAMT1;1 transcript in T-DNA insertion lines and of GFP-tagged chimeric-AtAMT1;1 transcript in transgenic lines.	Nitrogen	81-82	ammonium transporter 1;1	Arabidopsis thaliana	118-126
30106996-4	2018	It was also suggested that the underlying mechanism for synthesis was different between these N-acquiring enzymes in soil microorganisms: microbial LA and UR were primarily synthesized to acquire N, whereas NAG and PR syntheses were regulated not only by N availability but also by other factors.	Nitrogen	94-95	O-GlcNAcase	Homo sapiens	207-210
30690513-4	2019	ANAC032 reprograms carbon and nitrogen metabolism by increasing sugar and amino acid catabolism in plants.	Nitrogen	30-38	NAC domain containing protein 32	Arabidopsis thaliana	0-7
31901180-7	2020	A crucial role of 207 bp 3"-end sequence of AtAMT1;1 was further demonstrated by N-dependent accumulation of chimeric-AtAMT1;1 transcript in T-DNA insertion lines and of GFP-tagged chimeric-AtAMT1;1 transcript in transgenic lines.	Nitrogen	81-82	ammonium transporter 1;1	Arabidopsis thaliana	118-126
31459032-3	2018	Owing to the stress from lone pair electrons of N atom in the triethylamine bridge, these B(III) complexes exhibit unusual enantiomers with a tripodlike side-single-opening structure.	Nitrogen	48-49	calcium voltage-gated channel subunit alpha1 B	Homo sapiens	90-96
31901180-8	2020	A novel non-coding RNA (ncRNA), which was highly abundant in N-sufficient roots, may target the above-identified 3"-end region for degrading AtAMT1;1 transcript.	Nitrogen	20-21	ammonium transporter 1;1	Arabidopsis thaliana	141-149
29694257-5	2019	Thermal inactivation of FMO and CYP inhibition suggested that rat pulmonary N-oxygenation is predominantly FMO mediated while any contribution from CYPs is negligible.	Nitrogen	76-77	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	32-35
32123035-7	2020	Intriguingly, one of these sites lies on a 193 bp sequence found in three conserved locations on the large virulence plasmids of Shigella The region required for H-NS-dependent silencing of ospD1 lies between -1120 to -820 relative to the ospD1 +1.	Nitrogen	164-166	OspD1	Shigella flexneri	190-195
30933557-5	2019	These compounds, which include 4-chloropyridine and 4-chloronicotinamide, exploit the broad substrate scope of NNMT; methylation of the pyridine nitrogen enhances the electrophilicity of the C4 position, thereby promoting an aromatic nucleophilic substitution by C159, a noncatalytic cysteine.	Nitrogen	145-153	nicotinamide N-methyltransferase	Homo sapiens	111-115
30068157-6	2018	A large search over possible contraction schemes is done for the Li2 and Na2 molecules, and based on this search contracted pcJ-n basis sets for the four atoms are recommended.	Nitrogen	31-32	ATP binding cassette subfamily A member 12	Homo sapiens	65-68
32123035-7	2020	Intriguingly, one of these sites lies on a 193 bp sequence found in three conserved locations on the large virulence plasmids of Shigella The region required for H-NS-dependent silencing of ospD1 lies between -1120 to -820 relative to the ospD1 +1.	Nitrogen	164-166	OspD1	Shigella flexneri	239-244
29998261-1	2018	In this work, few-layer SnS2 nanosheets confined in a nitrogen-doped graphene sheet composite (SnS2/NGS) are successfully synthesized via a facile thermal decomposition method.	Nitrogen	54-62	sodium voltage-gated channel alpha subunit 11	Homo sapiens	24-28
32087767-3	2020	With the use of a small interfering RNA (siRNA)-mediated approach for selective downregulation of the four Arg/N-degron-dependent ubiquitin ligases, UBR1, UBR2, UBR4, and UBR5, we demonstrated decreased cell migration and proliferation and increased spontaneous apoptosis in cancer cells.	Nitrogen	37-38	ubiquitin protein ligase E3 component n-recognin 1	Mus musculus	149-153
29998261-1	2018	In this work, few-layer SnS2 nanosheets confined in a nitrogen-doped graphene sheet composite (SnS2/NGS) are successfully synthesized via a facile thermal decomposition method.	Nitrogen	54-62	sodium voltage-gated channel alpha subunit 11	Homo sapiens	95-99
29998261-2	2018	SnS2/NGS demonstrates sufficient nitrogen-doping and full graphene encapsulation.	Nitrogen	33-41	sodium voltage-gated channel alpha subunit 11	Homo sapiens	0-4
31002798-2	2019	SKN-1A/Nrf1, an endoplasmic reticulum (ER)-associated transcription factor that undergoes N-linked glycosylation, serves as a sensor of proteasome dysfunction and triggers compensatory upregulation of proteasome subunit genes.	Nitrogen	2-3	nuclear respiratory factor 1	Homo sapiens	7-11
32337418-1	2020	N-Linked glycosylation of the fragment crystallizable (Fc) domain of immunoglobulin G (IgG) is considered a significant modulator of antibody functions, which is known to be subclass-specific.	Nitrogen	0-1	immunoglobulin heavy variable V1-62	Mus musculus	69-85
30973873-5	2019	Dhh1 directly associates with ATG1 and ATG13 mRNAs under nitrogen-starvation conditions.	Nitrogen	57-65	unc-51 like autophagy activating kinase 1	Homo sapiens	30-34
30973873-8	2019	Moreover, eukaryotic translation initiation factor 4E (EIF4E)-associated protein 1 (Eap1), a target of rapamycin (TOR)-regulated EIF4E binding protein, physically interacts with Dhh1 after nitrogen starvation and facilitates the translation of Atg1 and Atg13.	Nitrogen	189-197	eukaryotic translation initiation factor 4E	Homo sapiens	10-53
30973873-8	2019	Moreover, eukaryotic translation initiation factor 4E (EIF4E)-associated protein 1 (Eap1), a target of rapamycin (TOR)-regulated EIF4E binding protein, physically interacts with Dhh1 after nitrogen starvation and facilitates the translation of Atg1 and Atg13.	Nitrogen	189-197	death domain associated protein	Homo sapiens	84-88
29697951-2	2018	Prior studies by us showed that increasing the N-alkyl chain length of N-substituted 4-MA analogues converts 4-MA from a transportable substrate (i.e., releaser) at DAT and NET to a nontransported blocker at these sites.	Nitrogen	47-48	solute carrier family 6 member 3	Rattus norvegicus	165-168
29697951-2	2018	Prior studies by us showed that increasing the N-alkyl chain length of N-substituted 4-MA analogues converts 4-MA from a transportable substrate (i.e., releaser) at DAT and NET to a nontransported blocker at these sites.	Nitrogen	71-72	solute carrier family 6 member 3	Rattus norvegicus	165-168
30973873-8	2019	Moreover, eukaryotic translation initiation factor 4E (EIF4E)-associated protein 1 (Eap1), a target of rapamycin (TOR)-regulated EIF4E binding protein, physically interacts with Dhh1 after nitrogen starvation and facilitates the translation of Atg1 and Atg13.	Nitrogen	189-197	neuroguidin	Homo sapiens	129-150
32337418-1	2020	N-Linked glycosylation of the fragment crystallizable (Fc) domain of immunoglobulin G (IgG) is considered a significant modulator of antibody functions, which is known to be subclass-specific.	Nitrogen	0-1	immunoglobulin heavy variable V1-62	Mus musculus	87-90
29939736-4	2018	N-Methylation of the imidazole pendants in [Fe(Mim)]3+ produces a complex that dissociates more readily at high pH in comparison to [Fe(Tim)]3+, which contains ionizable donor groups.	Nitrogen	0-1	MTSS I-BAR domain containing 1	Homo sapiens	47-50
32155053-4	2020	Gas sorption measurements revealed that this MOF possessed much higher uptake for Xe than for Kr, Ar, or N2 at room temperature in all pressure ranges.	Nitrogen	105-107	lysine acetyltransferase 8	Homo sapiens	45-48
29939736-4	2018	N-Methylation of the imidazole pendants in [Fe(Mim)]3+ produces a complex that dissociates more readily at high pH in comparison to [Fe(Tim)]3+, which contains ionizable donor groups.	Nitrogen	0-1	Rho guanine nucleotide exchange factor 5	Homo sapiens	136-139
29939736-8	2018	The crystal structure of [Fe(Mim)](OTf)3 shows a six-coordinate all-nitrogen bound Fe(III) in a distorted octahedral environment.	Nitrogen	68-76	MTSS I-BAR domain containing 1	Homo sapiens	29-32
30729676-5	2019	Renal miR-802 level was positively correlated with functional parameters, including blood urea nitrogen and creatinine in obese mice.	Nitrogen	95-103	microRNA 802	Mus musculus	6-13
32194222-9	2020	SESN2 gene expression was not significantly affected by n-3 PUFA supplementation although a slight up-regulation was observed.	Nitrogen	8-9	sestrin 2	Homo sapiens	0-5
30711708-7	2019	The exposure of A549 cells to Ag/N-TiO2 NPs determine the activation of ERK1/2 MAP-kinase pathway and the release of pro-inflammatory mediators CXCL1, GM-CSF and MIF, known to be involved in the recruitment of circulating neutrophils and monocytes.	Nitrogen	33-34	macrophage migration inhibitory factor	Homo sapiens	162-165
30615859-2	2019	Here, we synthesized the N-acetylated, C-end amidated and Cys-palmitated peptide (VLTCCFCICK KCLFKKKNKK K) which includes the fatty acylated cysteine residues in the membrane-affiliated domain of synaptotagmin-1.	Nitrogen	25-26	synaptotagmin 1	Homo sapiens	196-211
30369550-8	2019	SNIPER(BRD)-3 contained an N-methylated LCL-161 derivative as the IAP ligand, which prevented it from binding IAPs, and resulted in the abrogated degradation of cIAP1, XIAP, and BRD4.	Nitrogen	1-2	baculoviral IAP repeat containing 2	Homo sapiens	161-166
29992949-6	2018	Remarkably therefore, the TFEB NES integrates carbon (glucose) and nitrogen (amino acid) availability by controlling TFEB flux through a nuclear import-export cycle.	Nitrogen	67-75	transcription factor EB	Homo sapiens	26-30
29992949-6	2018	Remarkably therefore, the TFEB NES integrates carbon (glucose) and nitrogen (amino acid) availability by controlling TFEB flux through a nuclear import-export cycle.	Nitrogen	67-75	transcription factor EB	Homo sapiens	117-121
29932112-0	2018	N-Glycosylation Regulates Pannexin 2 Localization but Is Not Required for Interacting with Pannexin 1.	Nitrogen	0-1	pannexin 2	Homo sapiens	26-36
29932112-4	2018	Our objectives were to validate the predicted N-glycosylation site of Panx2 and to study the effects of Panx2 glycosylation on localization and its capacity to interact with Panx1.	Nitrogen	46-47	pannexin 2	Homo sapiens	70-75
29932112-6	2018	Our results showed that N86 is the only N-glycosylation site of Panx2.	Nitrogen	24-25	pannexin 2	Homo sapiens	64-69
31917875-4	2020	Magnocellular vasopressin (VP) neurons respond directly to hypertonic stimulation with membrane depolarization, which is triggered by cell shrinkage-induced opening of N terminal-truncated TRPV1 channels.	Nitrogen	168-169	transient receptor potential cation channel subfamily V member 1	Homo sapiens	189-194
29932112-9	2018	Our study indicates that N-glycosylation may be important for folding and trafficking of Panx2.	Nitrogen	25-26	pannexin 2	Homo sapiens	89-94
29525425-7	2018	PVP-Ag and Ag2S NPs had no effects on N2 release rates and the composition of denitrifiers, however, inhibited the emission of N2O (by reducing the abundance of nirK), suggesting that normal denitrification-induced N2 formation in sediments could still be sustained when the N2O production decrease lied within a certain range.	Nitrogen	127-129	angiotensin II receptor type 1	Homo sapiens	11-15
30239326-5	2019	Preconsumption food wastes Hpr and WM had more favorable C:N ratios (16.5-17.4) and crude fat contents (4.6-6.5%) as feedstock for composting.	Nitrogen	59-60	haptoglobin-related protein	Homo sapiens	27-30
31595631-4	2020	The only reported high-resolution structure is from the N-terminal domain of diamondback moth (DBM) RyR determined by our group.	Nitrogen	56-57	ryanodine receptor	Plutella xylostella	100-103
30564887-14	2019	Three iridium(III) complexes [Ir(N-C)2(PYTA)](PF6) (N-C = ppy, 1; bzq, 2; piq, 3) were synthesized and characterized.	Nitrogen	33-34	sperm associated antigen 17	Homo sapiens	46-49
29708761-2	2018	Such a strategy is achieved by the in situ and high-level doping of nitrogen atoms into carbon nanospheres (ANCS), which increases the carbon defects and active sites, inducing more rapidly capacitive charge-storage contributions for both Li+ storage anodes and PF6- storage cathodes.	Nitrogen	68-76	sperm associated antigen 17	Homo sapiens	262-265
32182407-2	2020	Herein, by controlling the solvent and mole ratio of cobalt/linker, multidimension-controllable MOF-derived nitrogen-doped carbon materials exhibit tunable morphology from sheet-, flower-, cube-, dodecahedron- to octahedron-like.	Nitrogen	108-116	lysine acetyltransferase 8	Homo sapiens	96-99
29888865-0	2018	In-depth comparison of N-glycosylation of human plasma-derived factor VIII and different recombinant products: from structure to clinical implications.	Nitrogen	23-24	coagulation factor VIII	Homo sapiens	63-74
29888865-10	2018	Seeking to better understand the glycosylation mechanisms underlying FVIII biology, we studied the N-glycosylation of human plasma-derived (pd)FVIII and six rFVIII products expressed in CHO, BHK or HEK cell lines.	Nitrogen	99-100	coagulation factor VIII	Homo sapiens	143-148
29889025-0	2018	N-glycosylation in the protease domain of trypsin-like serine proteases mediates calnexin-assisted protein folding.	Nitrogen	0-1	calnexin	Homo sapiens	81-89
30513349-0	2019	Glyco-engineered CHO cell lines producing alpha-1-antitrypsin and C1 esterase inhibitor with fully humanized N-glycosylation profiles.	Nitrogen	109-110	alpha-1-antitrypsin	Cricetulus griseus	42-61
29889025-3	2018	Here, we report a common mechanism of N-glycosylation in the protease domains of corin, enteropeptidase and prothrombin in calnexin-mediated glycoprotein folding and extracellular expression.	Nitrogen	38-39	transmembrane serine protease 15	Homo sapiens	88-103
32210322-3	2020	This report examined the feasibility of degrading ciprofloxacin and sulfamethoxazole through photoelectrocatalytic oxidation using FTO-BiVO4/Ag2S with p-n heterojunction as anode.	Nitrogen	17-18	angiotensin II receptor type 1	Homo sapiens	141-145
29889025-3	2018	Here, we report a common mechanism of N-glycosylation in the protease domains of corin, enteropeptidase and prothrombin in calnexin-mediated glycoprotein folding and extracellular expression.	Nitrogen	38-39	calnexin	Homo sapiens	123-131
29889025-5	2018	Elimination of N-glycosylation sites in the protease domains of corin, enteropeptidase and prothrombin inhibits corin and enteropeptidase cell surface expression and prothrombin secretion in transfected HEK293 cells.	Nitrogen	15-16	transmembrane serine protease 15	Homo sapiens	71-86
29889025-5	2018	Elimination of N-glycosylation sites in the protease domains of corin, enteropeptidase and prothrombin inhibits corin and enteropeptidase cell surface expression and prothrombin secretion in transfected HEK293 cells.	Nitrogen	15-16	transmembrane serine protease 15	Homo sapiens	122-137
29701969-8	2018	Particularly at intermediate W additions (W 500 mg kg-1), symbiotic nitrogen fixation was able to compensate for reduced leaf nitrate reductase activity.	Nitrogen	68-76	inducible nitrate reductase [NADH] 1	Glycine max	126-143
30853938-4	2019	Here we show that the dynamic and reversible O-linked beta-N-Acetyl-glucosaminylation (O-GlcNAcylation) regulates also cyclin D1 half-life.	Nitrogen	58-60	cyclin D1	Homo sapiens	119-128
32031799-1	2020	Myocyte enhancer factor 2 (MEF2; MEF2A-MEF2D) transcription factors regulate gene expression in a variety of developmental processes by binding to AT-rich DNA motifs via highly conserved N-terminal extensions known as MADS-box and MEF2 domains.	Nitrogen	156-157	myocyte enhancer factor 2A	Homo sapiens	0-25
30676594-1	2019	Herein, a series of N-doped carbon nanotube (CNx) samples were obtained by modifying the synthesis temperature.	Nitrogen	20-21	calnexin	Homo sapiens	45-48
29624891-5	2018	For OERs, the overpotential of Co@N-Carbon at 10 mA cm-2 was 400 mV (vs. reversible hydrogen electrode, RHE).	Nitrogen	34-35	factor interacting with PAPOLA and CPSF1	Homo sapiens	104-107
32031799-1	2020	Myocyte enhancer factor 2 (MEF2; MEF2A-MEF2D) transcription factors regulate gene expression in a variety of developmental processes by binding to AT-rich DNA motifs via highly conserved N-terminal extensions known as MADS-box and MEF2 domains.	Nitrogen	156-157	myocyte enhancer factor 2A	Homo sapiens	27-31
29624891-7	2018	The Tafel slope of Co@N-Carbon was 61 mV dec-1 , which is comparable to that of commercial RuO2 (58 mV dec-1 ).	Nitrogen	22-23	deleted in esophageal cancer 1	Homo sapiens	41-46
29624891-7	2018	The Tafel slope of Co@N-Carbon was 61 mV dec-1 , which is comparable to that of commercial RuO2 (58 mV dec-1 ).	Nitrogen	22-23	deleted in esophageal cancer 1	Homo sapiens	103-108
29870719-6	2018	Our results suggest that N-linked glycosylation sets the threshold of TNF receptor signaling by modifying ligand-receptor interactions and that cells may alter this modification to respond appropriately to physiological cues.	Nitrogen	25-26	eiger	Drosophila melanogaster	70-73
30589555-7	2019	This investigation evaluated halogen substitution effects on CYP2B6-catalyzed ketamine analogs N-demethylation in vitro and modeled interactions with CYP2B6 using various computational approaches.	Nitrogen	95-96	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	61-67
30472441-0	2019	Dual mode competitive electrochemical immunoassay for B-type natriuretic peptide based on GS/SnO2/polyaniline-Au and ZnCo2O4/N-CNTs.	Nitrogen	125-126	natriuretic peptide B	Homo sapiens	54-80
30472441-5	2019	N-doped carbon nanotubes (N-CNTs) embellished by ZnCo2O4 quantum dots (ZnCo2O4/N-CNTs) with excellent catalytic properties for the reduction of H2O2 was gotten to act as the label of the antibody-BNP (Ab), providing an obviously current signal through amperometric i-t curve method.	Nitrogen	0-1	natriuretic peptide B	Homo sapiens	196-199
32031799-1	2020	Myocyte enhancer factor 2 (MEF2; MEF2A-MEF2D) transcription factors regulate gene expression in a variety of developmental processes by binding to AT-rich DNA motifs via highly conserved N-terminal extensions known as MADS-box and MEF2 domains.	Nitrogen	156-157	myocyte enhancer factor 2A	Homo sapiens	33-37
30360131-5	2019	L6/QD complexes enter cells most efficiently when prepared at a nitrogen/phosphate ratio of 60.	Nitrogen	64-72	transmembrane 4 L six family member 1	Homo sapiens	0-5
28835463-0	2018	B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation.	Nitrogen	152-153	proteinase 3	Homo sapiens	67-71
32031799-2	2020	Despite the fact that MEF2 proteins exhibit high similarity at their N-terminal regions and share a common consensus DNA binding motif, their functional preferences may vary significantly in the adjacent regions to the DNA binding core segment.	Nitrogen	69-70	myocyte enhancer factor 2A	Homo sapiens	22-26
32184390-3	2020	The fate of glutamine nitrogen is shifted from the anaplerotic pathway into the TCA cycle to nucleotide biosynthesis, with this shift being controlled by glutaminase (GLS1) and phosphoribosyl pyrophosphate amidotransferase (PPAT).	Nitrogen	22-30	phosphoribosyl pyrophosphate amidotransferase	Homo sapiens	192-222
29446073-9	2018	Lack of Gr1high monocytes in Ccr2-deficient animals reduced neutrophil gelatinase-associated lipocalin and blood urea nitrogen levels.	Nitrogen	118-126	glutathione reductase	Mus musculus	8-11
30717150-1	2019	In this paper, a corrosion inhibitor containing nitrogen atoms and a conjugated pi bond was synthesised, and its final product synthesised by the optimal conditions of the orthogonal test results is named multi-mannich base (MBT).	Nitrogen	48-56	proteinase 3	Homo sapiens	225-228
30445264-5	2019	Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions.	Nitrogen	116-117	PC4 and SFRS1 interacting protein 1	Homo sapiens	204-207
30445264-5	2019	Molecular docking of the designed hybrids in CA IX active site unveiled, as planned, the ability of N-alkylated and N-benzylated isatin moieties to accommodate in a wide hydrophobic pocket formed by T73, P75, P76, L91, L123 and A128, establishing strong van der Waals interactions.	Nitrogen	116-117	phospholipase B domain containing 2	Homo sapiens	209-212
32184390-3	2020	The fate of glutamine nitrogen is shifted from the anaplerotic pathway into the TCA cycle to nucleotide biosynthesis, with this shift being controlled by glutaminase (GLS1) and phosphoribosyl pyrophosphate amidotransferase (PPAT).	Nitrogen	22-30	phosphoribosyl pyrophosphate amidotransferase	Homo sapiens	224-228
32157140-0	2020	Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176.	Nitrogen	50-51	G protein-coupled receptor 176	Homo sapiens	114-120
30621297-2	2019	We previously reported on alpha-ABpeptoids, oligomers of N-alkylated beta2-homoalanines and found that due to the presence of chiral methyl groups at alpha-positions, alpha-ABpeptoids were shown to adopt folding conformations.	Nitrogen	57-58	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	69-74
29401627-6	2018	We characterized the N-glycosylation profile of mouse colonic mucin (Muc)-2 by MS and showed that the interaction with mDectin-2 was mediated by high-mannose N-glycans.	Nitrogen	21-22	LOC100508689	Homo sapiens	62-67
32157140-4	2020	Here we show that Gpr176 is N-glycosylated.	Nitrogen	28-29	G protein-coupled receptor 176	Homo sapiens	18-24
29549127-10	2018	These findings provide a novel role for N-glycosylation of beta4-integrin in tumor development and progression, and the regulatory mechanism for beta4-integrin/PI3K signaling via the galectin-3-N-glycan complex.Implications:N-Glycosylation of beta4-integrin plays a functional role in promoting tumor development and progression through PI3K activation via the galectin-3-N-glycan complex.	Nitrogen	40-41	tubulin beta 3 class III	Homo sapiens	59-64
30510114-0	2019	The mitochondrial phosphatidylserine decarboxylase Psd1 is involved in nitrogen starvation-induced mitophagy in yeast.	Nitrogen	71-79	phosphatidylserine decarboxylase 1	Saccharomyces cerevisiae S288C	51-55
29549127-10	2018	These findings provide a novel role for N-glycosylation of beta4-integrin in tumor development and progression, and the regulatory mechanism for beta4-integrin/PI3K signaling via the galectin-3-N-glycan complex.Implications:N-Glycosylation of beta4-integrin plays a functional role in promoting tumor development and progression through PI3K activation via the galectin-3-N-glycan complex.	Nitrogen	194-195	tubulin beta 3 class III	Homo sapiens	145-150
32157140-5	2020	Peptide-N-glycosidase treatment of mouse hypothalamus extracts revealed that endogenous Gpr176 undergoes N-glycosylation.	Nitrogen	8-9	G protein-coupled receptor 176	Mus musculus	88-94
29549127-10	2018	These findings provide a novel role for N-glycosylation of beta4-integrin in tumor development and progression, and the regulatory mechanism for beta4-integrin/PI3K signaling via the galectin-3-N-glycan complex.Implications:N-Glycosylation of beta4-integrin plays a functional role in promoting tumor development and progression through PI3K activation via the galectin-3-N-glycan complex.	Nitrogen	194-195	tubulin beta 3 class III	Homo sapiens	145-150
30510114-6	2019	Through different approaches, we show that Psd1, the mitochondrial phosphatidylserine decarboxylase, is involved in mitophagy induction only after nitrogen starvation, whereas Psd2, which is located in vacuole, Golgi and endosome membranes, is required preferentially for mitophagy induction in the stationary phase of growth but also to a lesser extent for nitrogen starvation-induced mitophagy.	Nitrogen	147-155	phosphatidylserine decarboxylase 1	Saccharomyces cerevisiae S288C	43-47
30510114-6	2019	Through different approaches, we show that Psd1, the mitochondrial phosphatidylserine decarboxylase, is involved in mitophagy induction only after nitrogen starvation, whereas Psd2, which is located in vacuole, Golgi and endosome membranes, is required preferentially for mitophagy induction in the stationary phase of growth but also to a lesser extent for nitrogen starvation-induced mitophagy.	Nitrogen	358-366	phosphatidylserine decarboxylase 1	Saccharomyces cerevisiae S288C	43-47
30219496-0	2019	Effects of influent COD/TN ratio on nitrogen removal in integrated constructed wetland-microbial fuel cell systems.	Nitrogen	36-44	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	20-26
30219496-1	2019	Given that the relationship between the influent C/N (generally referred to as COD/TN) ratio and nitrogen removal has not been well understood in integrated constructed wetland-microbial fuel cell (CW-MFC) systems, this study aimed to investigate the effects of COD/TN ratio on nitrogen removal in CW-MFCs.	Nitrogen	97-105	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	79-85
29549127-10	2018	These findings provide a novel role for N-glycosylation of beta4-integrin in tumor development and progression, and the regulatory mechanism for beta4-integrin/PI3K signaling via the galectin-3-N-glycan complex.Implications:N-Glycosylation of beta4-integrin plays a functional role in promoting tumor development and progression through PI3K activation via the galectin-3-N-glycan complex.	Nitrogen	194-195	galectin 3	Homo sapiens	183-193
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	complement C1q B chain	Homo sapiens	181-185
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	carbonic anhydrase 12	Homo sapiens	230-234
32157140-6	2020	Using a heterologous expression system, we show that N-glycosylation occurs at four conserved asparagine residues in the N-terminal region of Gpr176.	Nitrogen	53-54	G protein-coupled receptor 176	Mus musculus	142-148
29573580-0	2018	Boosting ORR Catalytic Activity by Integrating Pyridine-N Dopants, a High Degree of Graphitization, and Hierarchical Pores into a MOF-Derived N-Doped Carbon in a Tandem Synthesis.	Nitrogen	56-57	lysine acetyltransferase 8	Homo sapiens	130-133
31984903-8	2019	CONCLUSION: Various N, S and O-alkyl derivatives of fluorine-substituted rhodanines were prepared via a simple method and used as enzymatic probes for cellobiase activity produced by fungi and CDK2 inhibitors for tumor cells.	Nitrogen	2-3	cyclin dependent kinase 2	Homo sapiens	193-197
32157140-10	2020	We also demonstrate that human GPR176 is N-glycosylated.	Nitrogen	41-42	G protein-coupled receptor 176	Homo sapiens	31-37
29573580-4	2018	With an N-containing MOF (ZIF-8) as the precursor, carbonization at higher temperatures leads to a higher degree of graphitization.	Nitrogen	8-9	lysine acetyltransferase 8	Homo sapiens	21-24
32157140-11	2020	Importantly, missense variations in the conserved N-glycosylation sites of human GPR176 (rs1473415441; rs761894953) affected N-glycosylation and thereby attenuated protein expression and cAMP-repressive activity in the cells.	Nitrogen	50-51	G protein-coupled receptor 176	Homo sapiens	81-87
29676158-6	2018	Compared to the isolated FAU and ZIF-8, a high yield of the product, 4-[5-(hydroxymethyl)furan-2-yl]but-3-en-2-one (67%), can be observed in the composite because of the synergistic effect between the Na+-stabilized zeolite framework and the imidazolate linkers bearing basic nitrogen functions.	Nitrogen	276-284	FAU ubiquitin like and ribosomal protein S30 fusion	Homo sapiens	25-28
30467756-3	2019	In phase II, the residual NH4+-N is further indirectly electrooxidized to nitrogen with modified Ti anode (Ti/SnO2-Sb-Pd).	Nitrogen	74-82	strawberry notch homolog 1	Homo sapiens	110-113
32157140-11	2020	Importantly, missense variations in the conserved N-glycosylation sites of human GPR176 (rs1473415441; rs761894953) affected N-glycosylation and thereby attenuated protein expression and cAMP-repressive activity in the cells.	Nitrogen	125-126	G protein-coupled receptor 176	Homo sapiens	81-87
32157140-12	2020	We show that N-glycosylation is a prerequisite for the efficient protein expression of functional Gpr176/GPR176.	Nitrogen	13-14	G protein-coupled receptor 176	Homo sapiens	98-104
29694013-2	2018	Hierarchically porous N-doped carbon polyhedrons anchored on crumpled graphene balls (NPC/CGBs) are synthesized by carbonizing a zeolitic imidazolate framework-8 (ZIF-8)/CGB composite precursor, producing an unprecedented effective host matrix for high-performance Li-Se batteries.	Nitrogen	22-23	chorionic gonadotropin subunit beta 5	Homo sapiens	90-93
32157140-12	2020	We show that N-glycosylation is a prerequisite for the efficient protein expression of functional Gpr176/GPR176.	Nitrogen	13-14	G protein-coupled receptor 176	Homo sapiens	105-111
30086385-10	2019	Inhalation of 100% N2 (anoxia) depressed breathing in both CSE null and wild-type mice.	Nitrogen	19-21	cystathionase (cystathionine gamma-lyase)	Mus musculus	59-62
31853635-3	2020	Here, we show that soluble aggregates of alpha-synuclein and tau bind to plate-immobilized PrP in vitro and on mouse cortical neurons, and that this binding requires at least one of the same N-terminal sites at which soluble Abeta aggregates bind.	Nitrogen	191-192	prion protein	Mus musculus	91-94
32254745-4	2018	In contrast, GGT catalyzed cascade reactions including cleavage of the gamma-glutamyl group and subsequent aromatic hydrocarbon transfer from the S to N atom increased the distance between the two chromophores, thus decreasing the FRET efficiency, with the recovery of the donor fluorescence at 461 nm.	Nitrogen	151-152	gamma-glutamyltransferase light chain 5 pseudogene	Homo sapiens	13-16
30584598-0	2018	Brain somatic mutations in SLC35A2 cause intractable epilepsy with aberrant N-glycosylation.	Nitrogen	76-77	solute carrier family 35 member A2	Homo sapiens	27-34
29743543-2	2018	In this study, the role of miR-23a in N-glycosylation and the metastasis of mouse hepatocellular carcinoma (HCC) cells was investigated.	Nitrogen	38-39	microRNA 23a	Mus musculus	27-34
31912347-1	2020	OBJECTIVE: The objective is to study the effect of individual N-glycosylation sequon on Suc2 activity and stability, and improve inulin conversion capacity and ethanol production of yeast by manipulating the key N-glycosylation sequon in Suc2.	Nitrogen	62-63	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	88-92
29717998-3	2018	Recombinant AKR1C3 with a thrombin-cleavable N-terminal His6 tag was expressed from a pET-28(+) vector for structural studies of enzyme-inhibitor complexes.	Nitrogen	45-46	aldo-keto reductase family 1 member C3	Homo sapiens	12-18
31912347-1	2020	OBJECTIVE: The objective is to study the effect of individual N-glycosylation sequon on Suc2 activity and stability, and improve inulin conversion capacity and ethanol production of yeast by manipulating the key N-glycosylation sequon in Suc2.	Nitrogen	62-63	beta-fructofuranosidase SUC2	Saccharomyces cerevisiae S288C	238-242
30340996-6	2018	The nanoESI MS analysis of neuraminic acids after treatment of BSM with NanS-p gave evidence that NanS-p variants of EHEC O157:H7 strain EDL933 cleave off O-acetyl groups from mono-, di-, and tri-O-acetylated Neu5Ac and N-glycolylneuraminic acid (Neu5Gc), regardless of the carbon positions C7, C8 or C9 of the acetate esters.	Nitrogen	72-73	N-acetylneuraminate synthase	Bos taurus	98-102
32044349-9	2020	Serum Metrnl levels were negatively correlated with VFA, total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C) and albumin (ALB), but positively correlated with age, height, blood urea nitrogen (BUN), creatinine (Cr) and uric acid (UA) (all P < 0.05).	Nitrogen	218-226	meteorin like, glial cell differentiation regulator	Homo sapiens	6-12
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	96-102
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	133-139
30362353-5	2018	Phosphorene quantum dots functionalized with nitrogen-containing groups (FPQDs) exhibit efficient and stable electrocatalytic activity for OER with an overpotential of 1.66 V @ 10 mA cm-2, a low Tafel slope of 48 mV dec-1, and excellent stability.	Nitrogen	45-53	deleted in esophageal cancer 1	Homo sapiens	216-221
29642572-1	2018	Nitrogen-doped graphene oxide sheets (N-GOs) are prepared by employing N-containing polymers such as polypyrrole, polyaniline, and copolymer (polypyrrole-polyaniline) doped with acids such as HCl, H2SO4, and C6H5-SO3-K, which are activated using different concentrations of KOH and carbonized at 650  C; characterized using SEM, TEM, BET, TGA-DSC, XRD, and XPS; and employed for the removal of environmental pollutant CO2.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	334-337
29642572-1	2018	Nitrogen-doped graphene oxide sheets (N-GOs) are prepared by employing N-containing polymers such as polypyrrole, polyaniline, and copolymer (polypyrrole-polyaniline) doped with acids such as HCl, H2SO4, and C6H5-SO3-K, which are activated using different concentrations of KOH and carbonized at 650  C; characterized using SEM, TEM, BET, TGA-DSC, XRD, and XPS; and employed for the removal of environmental pollutant CO2.	Nitrogen	0-8	T-box transcription factor 1	Homo sapiens	339-342
29642435-0	2018	Effects of N2 Partial Pressure on Growth, Structure, and Optical Properties of GaN Nanorods Deposited by Liquid-Target Reactive Magnetron Sputter Epitaxy.	Nitrogen	11-13	gigaxonin	Homo sapiens	79-82
29642435-4	2018	Yet, lower N2 partial pressures eventually led to the growth of continuous GaN films.	Nitrogen	11-13	gigaxonin	Homo sapiens	75-78
30532765-6	2018	We observed that FGF10 efficiently reduced I/R-induced elevation in blood urea nitrogen, serum creatinine as well as apoptosis induction of RTCs.	Nitrogen	79-87	fibroblast growth factor 10	Rattus norvegicus	17-22
31915857-4	2020	Here, we further investigated the formation of higher order structures of GRASP55 by exploring its amyloid fibrillation at 37  C. Sequence-based AGGRESCAN analysis revealed that GRASP55 has ten aggregation "hot spots", preferentially concentrated in its N-terminal half.	Nitrogen	153-154	golgi reassembly stacking protein 2	Homo sapiens	74-81
30301783-3	2018	We have previously reported that fission yeast (Schizosaccharomyces pombe) Tf2 retrotransposons (hereafter Tf2s) are abnormally induced upon nitrogen starvation in cells lacking the tsc2+ gene (Deltatsc2), a homolog of the human TSC2 gene, and in cells with a dominant-active mutation in the fission yeast RHEB GTPase (rhb1-DA4).	Nitrogen	141-149	Ras homolog, mTORC1 binding	Homo sapiens	306-310
29561002-7	2018	Zn-MOF 1 with openly accessible Lewis basic sites exhibited selective sorption of CO2 over N2, H2, and CH4 at low temperature.	Nitrogen	91-93	lysine acetyltransferase 8	Homo sapiens	3-6
31915857-4	2020	Here, we further investigated the formation of higher order structures of GRASP55 by exploring its amyloid fibrillation at 37  C. Sequence-based AGGRESCAN analysis revealed that GRASP55 has ten aggregation "hot spots", preferentially concentrated in its N-terminal half.	Nitrogen	153-154	golgi reassembly stacking protein 2	Homo sapiens	178-185
31822435-3	2020	After being cleaved by inflammatory caspases, it releases a N-terminal fragment with perforating activity to trigger pyroptosis.	Nitrogen	60-61	caspase 1	Mus musculus	36-44
29275151-5	2018	Out of these, NCDN and 14 genes were associated with spatial learning and nitrogen metabolism, respectively.	Nitrogen	74-82	neurochondrin	Latimeria chalumnae	14-18
29445807-0	2018	Base free N-alkylation of anilines with ArCH2OH and transfer hydrogenation of aldehydes/ketones catalyzed by the complexes of eta5-Cp*Ir(iii) with chalcogenated Schiff bases of anthracene-9-carbaldehyde.	Nitrogen	10-11	zinc finger and BTB domain containing 8 opposite strand	Homo sapiens	40-45
30746074-3	2019	Herein we present the first example of reversible HSe- binding in two distinct synthetic supramolecular receptors, using hydrogen bonds from N-H and aromatic C-H moieties.	Nitrogen	141-142	hydroxysteroid 17-beta dehydrogenase 6	Homo sapiens	50-53
32075754-4	2020	We show that the N terminus of Sen1 is both sufficient and necessary for replisome association and that it binds to the replisome via the components Ctf4 and Mrc1.	Nitrogen	17-18	mortality factor 4 (pseudogene)	Homo sapiens	31-35
30156471-2	2018	Npr1 (nitrogen permease reactivator) is a downstream effector kinase of TORC1 that regulates the stability, activity, and trafficking of various nutrient permeases including the ammonium permeases Mep1, Mep2, and Mep3 and the general amino acid permease Gap1.	Nitrogen	6-14	CREB regulated transcription coactivator 1	Homo sapiens	72-77
30321195-0	2018	NAM gene allelic composition and its relation to grain-filling duration and nitrogen utilisation efficiency of Australian wheat.	Nitrogen	76-84	NAC domain-containing protein 20	Triticum aestivum	0-3
30321195-2	2018	The present study was designed to investigate the associations between nitrogen utilisation efficiency (NUtE) and the allelic composition of the NAM genes in Australian wheat cultivars.	Nitrogen	71-79	NAC domain-containing protein 20	Triticum aestivum	145-148
28707979-5	2018	Recent Advances: New work has begun to elucidate the roles of SIRT5 in glycolysis, tricarboxylic acid cycle, fatty acid oxidation, nitrogen metabolism, pentose phosphate pathway, antioxidant defense, and apoptosis.	Nitrogen	131-139	sirtuin 5	Homo sapiens	62-67
32075754-4	2020	We show that the N terminus of Sen1 is both sufficient and necessary for replisome association and that it binds to the replisome via the components Ctf4 and Mrc1.	Nitrogen	17-18	mannose receptor C-type 1	Homo sapiens	158-162
30321195-3	2018	As results, the non-functional NAM-B1 allele was more responsive to the nitrogen levels and increased NUtE significantly, leading to a higher grain yield but reduced grain protein content.	Nitrogen	72-80	NAC domain-containing protein 20	Triticum aestivum	31-34
32079121-3	2020	In this work, we show that N starvation modifies poly(A) usage in a large number of transcripts, some of them mediated by FIP1, a component of the polyadenylation machinery.	Nitrogen	27-28	factor interacting with PAPOLA and CPSF1	Homo sapiens	122-126
30229632-5	2018	By contrast, the fungal community abundance and diversity indices showed the reverse, due to the high content of organic matter and nitrogen in lincomycin mycelia dreg.	Nitrogen	132-140	adhesion G protein-coupled receptor G6	Homo sapiens	163-167
29564399-7	2018	There is one ortholog of GZF3 and DAL80, which represses expression of genes in preferred nitrogen sources.	Nitrogen	90-98	Gzf3p	Saccharomyces cerevisiae S288C	25-29
32079121-7	2020	Meta-analyses of APA-affected and fip1-2-deregulated genes indicate a connection between the nitrogen starvation response and salicylic acid (SA) signaling.	Nitrogen	93-101	factor interacting with PAPOLA and CPSF1	Homo sapiens	34-38
29457354-3	2018	Instead of conventional N-containing sources or precursors, Schiff-base network (SNW-1) enables the desirable combination of a 3D polymer with intrinsic microporosity and ultrahigh N-content, which can significantly promote the fast transport of both Li+ and electron.	Nitrogen	24-25	SNW domain containing 1	Homo sapiens	81-86
29426894-0	2018	Site-specific N-glycosylation analysis of soluble Fcgamma receptor IIIb in human serum.	Nitrogen	14-15	Fc gamma receptor IIIb	Homo sapiens	50-71
29426894-2	2018	N-glycosylation of FcgammaRs critically affects their functions which is well exemplified by antibody-dependent cell-mediated cytotoxicity (ADCC) and phagocytosis mediated by homologous FcgammaRIIIa and FcgammaRIIIb, respectively.	Nitrogen	0-1	Fc gamma receptor IIIb	Homo sapiens	203-215
29992400-2	2018	However, the mechanism and actual role of autophagy in Tox N-induced apoptosis of human gastric cancer cells remains poorly understood.	Nitrogen	59-60	thymocyte selection associated high mobility group box	Homo sapiens	55-58
30822242-0	2018	Prediction of COPD and Related Events Improves by Combining Spirometry and the Single Breath Nitrogen Test.	Nitrogen	93-101	COPD	Homo sapiens	14-18
30822242-3	2018	The present study evaluated the prediction of COPD of a validated test for small airway disease, i.e. a slope of the alveolar plateau of the single breath nitrogen test (N2-slope).	Nitrogen	155-163	COPD	Homo sapiens	46-50
29426894-4	2018	Here we performed site-specific N-glycosylation profiling of a soluble form of FcgammaRIIIb purified from human serum based on mass spectrometric analysis.	Nitrogen	32-33	Fc gamma receptor IIIb	Homo sapiens	79-91
31759702-7	2020	(2) Among the nine cities in the PRD region, the average amounts of N pollution emission to the air, water, and soil all range from 0.57-5.38 kg cap-1 yr-1, showing significant discrepancy among cities.	Nitrogen	68-69	cyclase associated actin cytoskeleton regulatory protein 1	Homo sapiens	145-155
29426894-6	2018	Among the six N-glycosylation sites of serum soluble FcgammaRIIIb, Asn45 was shown to be exclusively occupied by high-mannose-type oligosaccharides, whereas the remaining sites were solely modified by the complex-type oligosaccharides with sialic acid and fucose residues.	Nitrogen	14-15	Fc gamma receptor IIIb	Homo sapiens	53-65
29531809-10	2018	The selective inhibition of nuNCX1 by XIP-NLS increased the percentage of beta III tubulin-positive immature neurons in mature cultures of MAP-2-positive cortical neurons, thus unraveling a new function for nuNCX1 in regulating neuronal differentiation through [Ca2+]n-dependent PTEN/PI3K/Akt pathway.	Nitrogen	15-16	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	Homo sapiens	38-41
30325144-4	2018	The results showed that N fertilizer application significantly increased the biomass and N uptake of February orchid under low soil inorganic N content (15 kg hm-2 in 0-90 cm soil layer).	Nitrogen	24-25	Putative anthocyanidin reductase	Zea mays	159-163
30325144-5	2018	At the application rate of 90 kg hm-2, the biomass (dry mass) and N uptake reached the maximum, being 2031 and 42 kg hm-2, respectively.	Nitrogen	66-67	Putative anthocyanidin reductase	Zea mays	33-37
30325144-5	2018	At the application rate of 90 kg hm-2, the biomass (dry mass) and N uptake reached the maximum, being 2031 and 42 kg hm-2, respectively.	Nitrogen	66-67	Putative anthocyanidin reductase	Zea mays	117-121
30325144-11	2018	While N uptake was at the highest level of 40 kg hm-2, the biomass of February orchid was 95% of the maximum biomass mentioned above (1919 kg hm-2) and the soil residual inorganic N before green manure incorporation decreased to 57 kg hm-2 whose corresponding minimum soil N supply amount was 105 kg hm-2.	Nitrogen	6-7	Putative anthocyanidin reductase	Zea mays	49-53
30325144-12	2018	This value was quite near to the recommended soil residual inorganic N (100 kg hm-2) after maize harvest under optimized N management in Nor-thern China.	Nitrogen	69-70	Putative anthocyanidin reductase	Zea mays	79-83
30325144-13	2018	Taken together, our results showed that the level of soil N supply should be at approximately 100 to 105 kg hm-2 in spring maize-winter green manure system for improving tradeoffs between agronomic and environmental impacts.	Nitrogen	58-59	Putative anthocyanidin reductase	Zea mays	108-112
31877497-13	2020	CRNDE knockdown in rats increased the urea nitrogen and serum creatinine in plasma.	Nitrogen	43-51	colorectal neoplasia differentially expressed	Rattus norvegicus	0-5
30181269-2	2018	Mammals have OST isoforms with STT3A or STT3B catalytic subunits for cotranslational or posttranslational N-glycosylation, respectively.	Nitrogen	106-107	MCF.2 cell line derived transforming sequence like	Homo sapiens	13-16
29231283-3	2018	Along this line, herein we report a series of neuraminidase inhibitors, having C4 (p-toluenesulfonamido and azido substituents) and C5 (N-perfluorinated chains) modifications to the DANA backbone, resulting in compounds with 5- to 15-fold greater potency than the currently most active compound, the N-trifluoroacetyl derivative of DANA (FANA), toward the NDV hemagglutinin-neuraminidase (NDV-HN).	Nitrogen	136-137	neuraminidase 1	Homo sapiens	46-59
30181269-13	2018	Without strict kinetic limitations during posttranslational N-glycosylation, STT3B-OST can thus moonlight for LLO hydrolysis.	Nitrogen	60-61	MCF.2 cell line derived transforming sequence like	Homo sapiens	83-86
31639410-0	2020	Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.	Nitrogen	0-8	chemokine (C-X-C motif) ligand 15	Mus musculus	99-103
30181269-14	2018	In contrast, the STT3A-OST/translocon complex preserves LLOs for temporally fastidious cotranslational N-glycosylation.	Nitrogen	103-104	MCF.2 cell line derived transforming sequence like	Homo sapiens	23-26
29092736-8	2018	In addition, positive correlations were identified between serum Bmi-1 levels and serum creatinine, blood urea nitrogen, cystatin C concentration, and the severity of tubulointerstitial fibrosis (r = 0.248, p &lt; 0.001; r = 0.245, p &lt; 0.001; r = 0.273, p &lt; 0.001; r = 0.536, p &lt; 0.001, respectively).	Nitrogen	111-119	BMI1 proto-oncogene, polycomb ring finger	Homo sapiens	65-70
31639410-8	2020	In conclusion, Fra-1 trapped in the cytoplasm after nitrogen mustard exposure might be a driving force for IL-8 over-expression in injured skin.	Nitrogen	52-60	chemokine (C-X-C motif) ligand 15	Mus musculus	107-111
30227620-4	2018	Thyroglobulin (Tg), the protein backbone for synthesis of thyroid hormones, is a heavily N-glycosylated protein, containing 20 putative N-glycosylated sites.	Nitrogen	89-90	thyroglobulin	Homo sapiens	0-13
31808794-0	2020	The N-terminal of NBPF15 causes multiple types of aggregates and mediates phase transition.	Nitrogen	4-5	NBPF member 15	Homo sapiens	18-24
30227620-4	2018	Thyroglobulin (Tg), the protein backbone for synthesis of thyroid hormones, is a heavily N-glycosylated protein, containing 20 putative N-glycosylated sites.	Nitrogen	89-90	thyroglobulin	Homo sapiens	15-17
30227620-4	2018	Thyroglobulin (Tg), the protein backbone for synthesis of thyroid hormones, is a heavily N-glycosylated protein, containing 20 putative N-glycosylated sites.	Nitrogen	136-137	thyroglobulin	Homo sapiens	0-13
30227620-4	2018	Thyroglobulin (Tg), the protein backbone for synthesis of thyroid hormones, is a heavily N-glycosylated protein, containing 20 putative N-glycosylated sites.	Nitrogen	136-137	thyroglobulin	Homo sapiens	15-17
29440987-6	2018	Pathway and enrichment analysis of non-targeted primary metabolite profiles from Sirt5-/- cortex revealed alterations in several pathways including purine metabolism (urea, adenosine, adenine, xanthine), nitrogen metabolism (glutamic acid, glycine), and malate-aspartate shuttle (malic acid, glutamic acid).	Nitrogen	204-212	sirtuin 5	Mus musculus	81-86
31808794-8	2020	We suggest that the entanglements between the mosaic disorder-ordered segments in NBPF15 N terminus have triggered the multiple types of aggregates and phase transition of NBPF15 proteins, which could be associated with Olduvai-related cognitive dysfunction diseases.	Nitrogen	82-83	NBPF member 15	Homo sapiens	172-178
29187599-2	2018	Human diamine oxidase (hDAO), required for histamine catabolism, has multiple N-glycosylation sites, but their roles, for example in DAO secretion, are unclear.	Nitrogen	78-79	amine oxidase copper containing 1	Homo sapiens	6-21
30097557-4	2018	Ivy1 is a negative regulator of Gtr-induced TORC1 activation, and is contained within puncta associated with the vacuolar membrane in cells grown in nutrient-rich medium or after brief nitrogen starvation.	Nitrogen	185-193	CREB regulated transcription coactivator 1	Homo sapiens	44-49
29980609-7	2018	One atypical and three conventional N-linked glycosylation sites in the AICL C-type lectin-like domain critically impact maturation and surfacing of AICL, which is strictly dependent on glycosylation of at least one conventional glycosylation site.	Nitrogen	36-37	C-type lectin domain family 2 member B	Homo sapiens	72-76
29980609-7	2018	One atypical and three conventional N-linked glycosylation sites in the AICL C-type lectin-like domain critically impact maturation and surfacing of AICL, which is strictly dependent on glycosylation of at least one conventional glycosylation site.	Nitrogen	36-37	C-type lectin domain family 2 member B	Homo sapiens	149-153
29980609-8	2018	However, although the extent of conventional N-linked glycosylation positively correlates with AICL surface expression, the atypical glycosylation site impairs AICL surfacing.	Nitrogen	45-46	C-type lectin domain family 2 member B	Homo sapiens	95-99
29449911-9	2018	In lupin-triticale mixture, a contrast in early growth strategies between species induced a higher total soil mineral N uptake compared with pure lupin.	Nitrogen	118-119	5'-nucleotidase, cytosolic IIIA	Homo sapiens	3-8
31996710-6	2020	pH-dependent OGR1-mediated signalling led to a significant upregulation in the ER stress markers, binding immunoglobulin protein (BiP) and phospho-inositol required 1alpha (IRE1alpha), which was reversed by a novel OGR1 inhibitor and a c-Jun N-terminal kinase (JNK) inhibitor.	Nitrogen	242-243	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	173-182
29456791-0	2018	Nonacidic Chemotype Possessing N-Acylated Piperidine Moiety as Potent Farnesoid X Receptor (FXR) Antagonists.	Nitrogen	0-1	nuclear receptor subfamily 1 group H member 4	Homo sapiens	92-95
31932450-6	2020	The superfusion of CeA slices with nociceptin/orphanin FQ peptide (N/OFQ; 500 nM), an endogenous opioid-like peptide, normalized GABA transmission in HA rats.	Nitrogen	67-68	carcinoembryonic antigen gene family 4	Rattus norvegicus	19-22
29924603-3	2018	The sulfur adducts formed are 1 (d-erythrose derivative):1 (nucleophile), and the nitrogen adducts are 1:2.	Nitrogen	82-90	VPS52 subunit of GARP complex	Homo sapiens	99-104
31932450-9	2020	These results demonstrate that the downregulation of N/OFQ levels in the CeA may be responsible for hyper-GABAergic tone in the CeA that is observed in individuals who develop addiction-like behaviors.	Nitrogen	53-54	carcinoembryonic antigen gene family 4	Rattus norvegicus	73-76
30033729-4	2018	Synthetic utility of this process was highlighted through the production of diverse nitrogen heterocycles and an orexin receptor antagonist.	Nitrogen	84-92	hypocretin neuropeptide precursor	Homo sapiens	113-119
29493463-2	2018	Excessive formation of reactive oxygen species (ROS) and nitrogen (RNSs) can overburden the ability of the enzymatic antioxidant defense mechanisms (superoxide dismutase, catalase and glutathione reductase) and non-enzymatic (uric acid, ascorbic acid, alpha-tocopherol and reduced glutathione), causing the development of oxidative stress, and consequently, impairing the neuronal system cells by means of oxidative damage to a variety of important biological molecules such as lipids, DNA and proteins.	Nitrogen	57-65	glutathione-disulfide reductase	Homo sapiens	184-205
31932450-9	2020	These results demonstrate that the downregulation of N/OFQ levels in the CeA may be responsible for hyper-GABAergic tone in the CeA that is observed in individuals who develop addiction-like behaviors.	Nitrogen	53-54	carcinoembryonic antigen gene family 4	Rattus norvegicus	128-131
31978132-8	2020	High-resolution fluorescence microscopy, T3SS activity, and virulence phenotype analyses of Shigella strains co-expressing wild-type Spa47 and the ATPase inactive Spa47 mutants demonstrate that the N-terminus of Spa47, not ATPase activity, is responsible for incorporation into the injectisome where the mutant strains exhibit a dominant negative effect on T3SS function and Shigella virulence.	Nitrogen	198-199	dynein axonemal heavy chain 8	Homo sapiens	147-153
29146600-9	2018	CONCLUSIONS: Higher HbA1c in type 1 diabetes is associated with changes in the serum N-glycome that have elsewhere been shown to regulate the epidermal growth factor receptor and transforming growth factor-beta pathways that are implicated in DKD.	Nitrogen	2-3	hemoglobin subunit alpha 1	Homo sapiens	20-24
31950662-6	2018	It is noteworthy that one of the N-trinitromethyl nitroimidazole derivatives showed high density (rho: 1.88 g cm-3 ), attractive positive oxygen balance (Omega: +18.3 %) and good detonation performance (D: 9003 m s-1 ) exceeding those of ADN, while N-nitromethyl derivative behaved higher thermal stability and lower sensitivity in contrast to those of NG.	Nitrogen	33-34	complement factor D	Homo sapiens	238-241
31978132-8	2020	High-resolution fluorescence microscopy, T3SS activity, and virulence phenotype analyses of Shigella strains co-expressing wild-type Spa47 and the ATPase inactive Spa47 mutants demonstrate that the N-terminus of Spa47, not ATPase activity, is responsible for incorporation into the injectisome where the mutant strains exhibit a dominant negative effect on T3SS function and Shigella virulence.	Nitrogen	198-199	dynein axonemal heavy chain 8	Homo sapiens	223-229
29997239-8	2018	We conclude that peroxisomal MDH2 helps photoautotrophs cope with nitrogen scarcity and high light by transmitting the redox state of the peroxisome to the chloroplast by means of malate shuttle- and H2O2-based redox signaling.	Nitrogen	66-74	uncharacterized protein	Chlamydomonas reinhardtii	29-33
31963398-6	2020	To that aim, cold atmospheric plasma jets were used to obtain PAR, which produced cytotoxic effects in human OS cells (SaOS-2, MG-63, and U2-OS), related to the increasing concentration of reactive oxygen and nitrogen species generated.	Nitrogen	209-217	AFG3-like AAA ATPase 2	Mus musculus	62-65
29853337-0	2018	Pyrroloquinoline scaffold-based 5-HT6R ligands: Synthesis, quantum chemical and molecular dynamic studies, and influence of nitrogen atom position in the scaffold on affinity.	Nitrogen	124-132	5-hydroxytryptamine receptor 6	Homo sapiens	32-38
29120059-7	2018	Relationship between source and sink nitrogen transport processes and metabolism 43 VIII.	Nitrogen	37-45	cytochrome c oxidase subunit 8A	Homo sapiens	84-88
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	32-33	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	178-185
29261164-4	2017	In the acute advanced phase, the IL-18Ralpha KO mice showed a higher survival rate and a suppressed increase of blood urea nitrogen, increased levels of proinflammatory cytokines such as IFN-gamma and IL-18, the infiltration of CD4+ T cells and the expression of kidney injury molecule-1 as an AKI marker.	Nitrogen	123-131	interleukin 18 receptor 1	Mus musculus	33-44
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	32-33	fucosyltransferase 8	Homo sapiens	241-245
29261164-4	2017	In the acute advanced phase, the IL-18Ralpha KO mice showed a higher survival rate and a suppressed increase of blood urea nitrogen, increased levels of proinflammatory cytokines such as IFN-gamma and IL-18, the infiltration of CD4+ T cells and the expression of kidney injury molecule-1 as an AKI marker.	Nitrogen	123-131	interleukin 18	Mus musculus	33-38
29147551-0	2017	Development of proteolytically stable N-methylated peptide inhibitors of aggregation of the amylin peptide implicated in type 2 diabetes.	Nitrogen	38-39	islet amyloid polypeptide	Homo sapiens	92-98
29208962-4	2017	Herein we present azomethine ylide homocoupling as a strategy to afford internally nitrogen-doped, non-planar PAH in solution and planar nanographene on surfaces, with central pyrazine rings.	Nitrogen	83-91	phenylalanine hydroxylase	Homo sapiens	110-113
29656185-5	2018	Moreover, SERP1 enhanced GLP-1R N-glycosylation and increased the production of phosphorylated endothelial nitric oxide synthase (eNOS) as well as proliferation of RAOECs.	Nitrogen	32-33	stress-associated endoplasmic reticulum protein 1	Rattus norvegicus	10-15
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	insulin-like growth factor 1 receptor	Capra hircus	228-241
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	insulin-like growth factor 1 receptor	Capra hircus	243-248
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	130-131	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	178-185
29949951-2	2018	A new series of N"-substituted derivatives of 5-amino-N,3-dimethyl-1,2-oxazole-4-carbohydrazide (MM1-MM10) was synthesized in reaction of 5-amino-N,3-dimethyl-1,2-oxazole-4-carbohydrazide with relevant carbonyl compounds.	Nitrogen	16-18	prefoldin subunit 5	Homo sapiens	97-100
31936666-4	2020	In particular, the formation of N-glycan branches regulates the functions of target glycoprotein, which are catalyzed by specific N-acetylglucosaminyltransferases (GnTs) such as GnT-III, GnT-IVs, GnT-V, and GnT-IX, and a fucosyltransferase, FUT8s.	Nitrogen	130-131	fucosyltransferase 8	Homo sapiens	241-245
33025683-7	2020	RFI class did not interfere with enteric methane production or microbial protein synthesis, but fecal nitrogen output was higher in low RFI animals.	Nitrogen	102-110	RFI	Bos taurus	136-139
29967628-6	2018	Consistent with a role for PtdIn-3-phosphate in autophagy, vps38 mutants are hypersensitive to nitrogen and fixed-carbon starvation and show reduced autophagic transport of cargo into vacuoles.	Nitrogen	95-103	Vps38p	Saccharomyces cerevisiae S288C	59-64
29693380-2	2018	To explore this opportunity, we developed a highly efficient route to introduce nitrogen-based functionalities at the naturally unsubstituted C-3 position on the neuraminidase inhibitor template N-acyl-2,3-dehydro-2-deoxy-neuraminic acid ( N-acyl-Neu2en), via a regioselective 2,3-bromoazidation.	Nitrogen	80-88	neuraminidase 1	Homo sapiens	162-175
28926062-4	2017	The PPL and ENVI-Carb cartridges can recover representative nitrogen-containing organic components from the hypersaline lake.	Nitrogen	60-68	syntaxin 8	Homo sapiens	17-21
29259749-3	2017	Three crystal structures are reported for complexes of MIF with 3a, 4a, and 4b, which show that the desired hydrogen bond is formed with O-N distances of 2.8-3.0 A.	Nitrogen	139-140	macrophage migration inhibitory factor	Homo sapiens	55-58
31642335-5	2020	In addition, the N-terminus (amino acids 43-86) of PIAS3 bound nNOS directly.	Nitrogen	17-18	nitric oxide synthase 1	Homo sapiens	63-67
29045155-0	2017	Diamine-Appended Mg2(dobpdc) Nanorods as Phase-Change Fillers in Mixed-Matrix Membranes for Efficient CO2/N2 Separations.	Nitrogen	106-108	mucin 7, secreted	Homo sapiens	17-20
29902282-5	2018	Further, the N-glycosylation pathway in the NB_1(-Mgat2) cell line was rescued by transiently transfecting cells with Mgat2, thus creating the NB_1(-/+Mgat2) cell line.	Nitrogen	13-14	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	50-55
29072837-5	2017	The integrated PSF-ZIF@MOF hybrid membrane (40 wt % loading) with optimized ZIF coating cycles showed improved hydrophobicity and excellent CO2 separation performance by simultaneously increasing CO2 permeability (CO2 permeability of 45.2 barrer, 710% higher than PSF membrane) and CO2/N2 selectivity (CO2/N2 selectivity of 39, 50% higher than PSF membrane), which is superior to most reported hybrid PSF membranes.	Nitrogen	286-288	lysine acetyltransferase 8	Homo sapiens	15-26
29902282-5	2018	Further, the N-glycosylation pathway in the NB_1(-Mgat2) cell line was rescued by transiently transfecting cells with Mgat2, thus creating the NB_1(-/+Mgat2) cell line.	Nitrogen	13-14	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	118-123
31561038-7	2020	Molecular dissection of the WNK1 domains revealed that the WNK1 kinase domain is responsible for CFTR PHCO3/PCl regulation by direct association with CFTR, while the surrounding N-terminal regions mediate the [Cl-]i-sensitivity of WNK1.	Nitrogen	29-30	WNK lysine deficient protein kinase 1	Homo sapiens	59-63
29902282-5	2018	Further, the N-glycosylation pathway in the NB_1(-Mgat2) cell line was rescued by transiently transfecting cells with Mgat2, thus creating the NB_1(-/+Mgat2) cell line.	Nitrogen	13-14	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	118-123
29072837-5	2017	The integrated PSF-ZIF@MOF hybrid membrane (40 wt % loading) with optimized ZIF coating cycles showed improved hydrophobicity and excellent CO2 separation performance by simultaneously increasing CO2 permeability (CO2 permeability of 45.2 barrer, 710% higher than PSF membrane) and CO2/N2 selectivity (CO2/N2 selectivity of 39, 50% higher than PSF membrane), which is superior to most reported hybrid PSF membranes.	Nitrogen	306-308	lysine acetyltransferase 8	Homo sapiens	15-26
31561038-7	2020	Molecular dissection of the WNK1 domains revealed that the WNK1 kinase domain is responsible for CFTR PHCO3/PCl regulation by direct association with CFTR, while the surrounding N-terminal regions mediate the [Cl-]i-sensitivity of WNK1.	Nitrogen	29-30	WNK lysine deficient protein kinase 1	Homo sapiens	59-63
29106622-0	2017	A light-sensitive mutation in Arabidopsis LEW3 reveals the important role of N-glycosylation in root growth and development.	Nitrogen	77-78	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	42-46
30083263-13	2018	Tid1 interacted with Galectin-7 through its N-linked glycosylation to promote Tid1-mediated ubiquitination and proteasomal degradation of Galectin-7.	Nitrogen	44-45	DnaJ heat shock protein family (Hsp40) member A3	Homo sapiens	0-4
30083263-13	2018	Tid1 interacted with Galectin-7 through its N-linked glycosylation to promote Tid1-mediated ubiquitination and proteasomal degradation of Galectin-7.	Nitrogen	44-45	DnaJ heat shock protein family (Hsp40) member A3	Homo sapiens	78-82
31733588-1	2020	The N-terminal von Willebrand domain of Ku80 supports interactions with a Ku binding motif (KBM) that has been identified in at least three other DNA repair proteins: the non-homologous end joining (NHEJ) scaffold APLF, the modulator of retrovirus infection, MRI, and the Werner syndrome protein (WRN).	Nitrogen	4-5	X-ray repair cross complementing 5	Homo sapiens	40-44
29741757-4	2018	To identify the galectin-3-binding site, we used mass spectrometry to show that CD146 eFL has four N-glycosites, with PNGase F treatment indicating that N-glycans define the binding epitope.	Nitrogen	99-100	galectin 3	Homo sapiens	16-26
29718541-6	2018	Both participate in Nox1 trafficking, as Nox1 advances to the cell surface in two differentially N-glycosylated forms, one complex and one high mannose, in a Sar1/Stx5-dependent and -independent manner, respectively.	Nitrogen	20-21	NADPH oxidase 1	Homo sapiens	41-45
29106622-3	2017	Positional cloning determined that lrg1 affects an alpha-1,2-mannosyltransferase gene, LEW3, involved in protein N-glycosylation.	Nitrogen	113-114	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	87-91
29058647-1	2017	Yeast cells can use gamma-aminobutyric acid (GABA), a non-protein amino acid, as a nitrogen source that is mainly imported by the permease Uga4 and catabolized by the enzymes GABA transaminase and succinate-semialdehyde dehydrogenase, encoded by the UGA1 and UGA2 genes, respectively.	Nitrogen	83-91	4-aminobutyrate transaminase	Saccharomyces cerevisiae S288C	250-254
29058647-1	2017	Yeast cells can use gamma-aminobutyric acid (GABA), a non-protein amino acid, as a nitrogen source that is mainly imported by the permease Uga4 and catabolized by the enzymes GABA transaminase and succinate-semialdehyde dehydrogenase, encoded by the UGA1 and UGA2 genes, respectively.	Nitrogen	83-91	succinate-semialdehyde dehydrogenase (NAD(P)(+))	Saccharomyces cerevisiae S288C	259-263
28775154-0	2017	A genome-wide CRISPR screen reconciles the role of N-linked glycosylation in galectin-3 transport to the cell surface.	Nitrogen	51-52	galectin 3	Homo sapiens	77-87
28775154-3	2017	Here, using a genome-wide CRISPR/Cas9 forward genetic screen for regulators of Gal-3 cell surface localization, we identified genes encoding glycoproteins, enzymes involved in N-linked glycosylation, regulators of ER-Golgi trafficking and proteins involved in immunity.	Nitrogen	176-177	galectin 3	Homo sapiens	79-84
28775154-4	2017	The results of this screening approach led us to address the controversial role of N-linked glycosylation in the transport of Gal-3 to the cell surface.	Nitrogen	83-84	galectin 3	Homo sapiens	126-131
29549127-3	2018	Here, N-glycosylation of beta4-integrin contributes to the activation of signaling pathways that promote beta4-dependent tumor development and progression.	Nitrogen	6-7	tubulin beta 3 class III	Homo sapiens	25-30
29549127-3	2018	Here, N-glycosylation of beta4-integrin contributes to the activation of signaling pathways that promote beta4-dependent tumor development and progression.	Nitrogen	6-7	tubulin beta 3 class III	Homo sapiens	105-110
31733588-1	2020	The N-terminal von Willebrand domain of Ku80 supports interactions with a Ku binding motif (KBM) that has been identified in at least three other DNA repair proteins: the non-homologous end joining (NHEJ) scaffold APLF, the modulator of retrovirus infection, MRI, and the Werner syndrome protein (WRN).	Nitrogen	4-5	WRN RecQ like helicase	Homo sapiens	272-295
31733588-1	2020	The N-terminal von Willebrand domain of Ku80 supports interactions with a Ku binding motif (KBM) that has been identified in at least three other DNA repair proteins: the non-homologous end joining (NHEJ) scaffold APLF, the modulator of retrovirus infection, MRI, and the Werner syndrome protein (WRN).	Nitrogen	4-5	WRN RecQ like helicase	Homo sapiens	297-300
29974703-4	2018	The enhancement of soil fertility was highest at 300 kg N hm-2, with significant increases of the contents of soil organic matter, total N, alkali-hydrolyzable-N, available P, and available K by 12.8%, 31.6%, 11.6%, 20.6% and 74.2%, respectively.	Nitrogen	56-57	Putative anthocyanidin reductase	Zea mays	58-62
28734141-4	2017	Reactions of Pd1 with Tu, l-Met and l-Cys were followed by decomposition of complexes, while structures of dinuclear complexes were preserved during the substitution with nitrogen donors.	Nitrogen	171-179	programmed cell death 1	Homo sapiens	13-16
31810587-7	2020	SDC1 binds to various ligands and influences the growth and reproduction of cancer cells via the activation of Wnt, the long isoform of FLICE-inhibitory protein (FLIP long), vascular endothelial growth factor receptor (VEGFR), mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) and MAPK/c-Jun N-terminal kinase (JNK) and other pathways.	Nitrogen	326-327	syndecan 1	Homo sapiens	0-4
29624869-2	2018	Optical measurements showed that BAz worked as a strong electron acceptor because of the intrinsic electron deficiency of the N=N double bond and the boron-nitrogen (B-N) coordination which dramatically lowered the energy of the lowest unoccupied molecular orbital (LUMO) of the azobenzene ligand.	Nitrogen	156-164	par-3 family cell polarity regulator	Homo sapiens	33-36
31950785-10	2020	After transfection of Eca109 cells with HOXA1 ASODN, the viability of Eca109 cells decreased with the increase of concentration and time, the difference was significant compared with the control, SODN and N-ODN groups ( P&lt;0.05).	Nitrogen	50-51	homeobox A1	Homo sapiens	40-45
29719149-1	2018	Among the many metal-dinitrogen complexes synthesized, the end-on bridging (mu2, eta1, eta1-N2) coordination mode is notoriously unreactive for nitrogen fixation.	Nitrogen	21-31	adaptor related protein complex 1 subunit mu 2	Homo sapiens	76-79
29719149-1	2018	Among the many metal-dinitrogen complexes synthesized, the end-on bridging (mu2, eta1, eta1-N2) coordination mode is notoriously unreactive for nitrogen fixation.	Nitrogen	23-31	adaptor related protein complex 1 subunit mu 2	Homo sapiens	76-79
28916765-3	2017	This step requires protonation by a conserved aspartate of the pyridine nitrogen of PLP to enhance its ability to stabilize the carbanionic intermediate.	Nitrogen	72-80	pyridoxal phosphatase	Homo sapiens	84-87
31886770-5	2019	The flexible ATPase lobe, composed of helicase subunit Sth1, Arp7, Arp9 and Rtt102, is anchored to this core by the N-terminus of Sth1.	Nitrogen	116-117	RSC chromatin remodeling complex ATPase subunit STH1	Saccharomyces cerevisiae S288C	55-59
28928722-6	2017	At high Lac/N ratio (2.97 mol/mol) both fermentative and respiratory nitrate reduction to ammonium occurred, coupled to partial oxidation of lactate to acetate, and to acetate oxidation respectively.	Nitrogen	12-13	lactase	Homo sapiens	8-11
28928722-8	2017	At a decreased Lac/N ratio (1.15 mol/mol), the molar percentage of nitrate reduced to ammonium decreased to 58%, even though lactate was supplied in adequate amounts for full ammonification and nitrate remained the growth limiting compound.	Nitrogen	19-20	lactase	Homo sapiens	15-18
29669921-3	2018	Herein, we describe the design, synthesis, and evaluation of a collection of N-arylated benzimidazole derivatives (BIMs), one of which (BIM1) shows unparalleled (&gt;20-fold) selectivity for CLC-Ka over CLC-Kb, the two most closely related human CLC homologs.	Nitrogen	77-78	chloride voltage-gated channel Kb	Homo sapiens	203-209
29717320-0	2018	An anionic eta2-naphthalene complex of titanium supported by a tripodal [O3C] ligand and its reactions with dinitrogen, anthracene and THF.	Nitrogen	108-118	DNA polymerase iota	Homo sapiens	11-15
29717320-2	2018	The eta2-naphthalene ligand is readily displaced by N2 and anthracene along with the release of free naphthalene, resulting in the formation of the end-on N2 bridging dititanium complex and the anthracene complex, respectively.	Nitrogen	52-54	DNA polymerase iota	Homo sapiens	4-8
31886770-5	2019	The flexible ATPase lobe, composed of helicase subunit Sth1, Arp7, Arp9 and Rtt102, is anchored to this core by the N-terminus of Sth1.	Nitrogen	116-117	Arp7p	Saccharomyces cerevisiae S288C	61-65
29846664-5	2018	Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms.	Nitrogen	102-110	calnexin	Homo sapiens	85-88
29509193-0	2018	Label-free fluorescence imaging of cytochrome c in living systems and anti-cancer drug screening with nitrogen doped carbon quantum dots.	Nitrogen	102-110	cytochrome c, somatic b	Danio rerio	35-47
29509193-3	2018	Here, we designed a novel label-free N-doped carbon dot (N-doped CD)-based nanosensor that enables fluorescence activation imaging of Cyt c release in cell apoptosis.	Nitrogen	37-38	cytochrome c, somatic b	Danio rerio	134-139
28272772-1	2017	The tumour suppressor candidate 3 (TUSC3) gene is located on chromosome region 8p22 and encodes the 34 kD TUSC3 protein, which is a subunit of the oligosaccharyl transferase responsible for the N-glycosylation of nascent proteins.	Nitrogen	194-195	tumor suppressor candidate 3	Homo sapiens	4-33
28272772-1	2017	The tumour suppressor candidate 3 (TUSC3) gene is located on chromosome region 8p22 and encodes the 34 kD TUSC3 protein, which is a subunit of the oligosaccharyl transferase responsible for the N-glycosylation of nascent proteins.	Nitrogen	194-195	tumor suppressor candidate 3	Homo sapiens	35-40
28272772-1	2017	The tumour suppressor candidate 3 (TUSC3) gene is located on chromosome region 8p22 and encodes the 34 kD TUSC3 protein, which is a subunit of the oligosaccharyl transferase responsible for the N-glycosylation of nascent proteins.	Nitrogen	194-195	tumor suppressor candidate 3	Homo sapiens	106-111
28710913-5	2017	The level of Sdh1-2 transcripts in seedlings declined significantly under N2 and even more rapidly upon exposure to CO2, with a concomitant increase in methylation of the corresponding promoters.	Nitrogen	74-76	sorbitol dehydrogenase homolog 1	Zea mays	13-19
31886770-5	2019	The flexible ATPase lobe, composed of helicase subunit Sth1, Arp7, Arp9 and Rtt102, is anchored to this core by the N-terminus of Sth1.	Nitrogen	116-117	RSC chromatin remodeling complex ATPase subunit STH1	Saccharomyces cerevisiae S288C	130-134
31892185-0	2019	Independent Impact of Gynoid Fat Distribution and Free Testosterone on Circulating Levels of N-Terminal Pro-Brain Natriuretic Peptide (NT-proBNP) in Humans.	Nitrogen	93-94	natriuretic peptide B	Homo sapiens	108-133
28617578-6	2017	Using synthetic MUC16 glycopeptides, we developed novel N-glycosylation site directed monoclonal antibodies that block Galectin-3-mediated MUC16 interactions with cell surface signaling molecules.	Nitrogen	56-57	galectin 3	Homo sapiens	119-129
28864370-8	2017	In the overall analysis, pro-BNP level significantly correlated with red blood cell (RBC), platelet, ascites, blood urea nitrogen (BUN), creatinine (Cr), Child-Pugh score, model for end-stage liver disease (MELD) score and in-hospital death; TnT-HSST level significantly correlated with white blood cell, ascites, albumin (ALB), BUN, Cr, Child-Pugh score, MELD score and in-hospital death.	Nitrogen	121-129	natriuretic peptide B	Homo sapiens	29-32
29498673-4	2018	Remarkably, though, despite the fact that all membrane-bound TRAIL receptors harbor putative glycosylation sites, only pro-apoptotic signaling through DR4 and DR5 has, so far, been found to be regulated by N- and O-glycosylation, respectively.	Nitrogen	206-207	TNF receptor superfamily member 10a	Homo sapiens	151-154
29323465-3	2018	Time course induction of ER stress, using tunicamycin (TM), shows a group of genes such as Chop, Trb3, Sqstm1, Grp78, and Herpud1 respond rapidly to TM inhibition of N-glycosylation, while others such as Atf5, Odz4, and Birc5 exhibits a delayed response.	Nitrogen	166-167	sequestosome-1	Cricetulus griseus	103-109
29323465-3	2018	Time course induction of ER stress, using tunicamycin (TM), shows a group of genes such as Chop, Trb3, Sqstm1, Grp78, and Herpud1 respond rapidly to TM inhibition of N-glycosylation, while others such as Atf5, Odz4, and Birc5 exhibits a delayed response.	Nitrogen	166-167	survivin	Cricetulus griseus	220-225
31765120-1	2019	Nitrogen (N)-doped nanocarbons (NDN) as metal-free catalysts have elicited considerable attention toward selective oxidation of alcohols with easily oxidizable groups to aldehydes in the past few years.	Nitrogen	0-8	necdin, MAGE family member	Homo sapiens	32-35
29459785-2	2018	The enzyme UDP-N-acetylglucosamine:dolichyl-phosphate N-acetylglucosaminephosphotransferase (GlcNAc-1-P-transferase or GPT) catalyzes the first and committed step of N-linked glycosylation in the endoplasmic reticulum membrane, and it is the target of the natural product tunicamycin.	Nitrogen	15-16	glutamic--pyruvic transaminase	Homo sapiens	119-122
28318752-7	2017	CSE deficient mice, compared to wild-type mice, showed a significant attenuation of the burn-induced elevation in circulating alkaline aminotransferase and blood urea nitrogen and creatinine levels, indicative of protective effects of CSE deficiency against burn-induced hepatic, and renal functional impairment.	Nitrogen	167-175	cystathionase (cystathionine gamma-lyase)	Mus musculus	0-3
31765120-1	2019	Nitrogen (N)-doped nanocarbons (NDN) as metal-free catalysts have elicited considerable attention toward selective oxidation of alcohols with easily oxidizable groups to aldehydes in the past few years.	Nitrogen	0-1	necdin, MAGE family member	Homo sapiens	32-35
31765120-5	2019	The results of XPS and x-ray absorption near edge structure spectra suggest that the dominating N species on NDN are pyridinic N.	Nitrogen	96-97	necdin, MAGE family member	Homo sapiens	109-112
31697501-2	2019	Correlating simulations with experimental data from SPR kinetics measurements and X-ray crystallography on two small molecule compound libraries bound to the N-terminal domain of the chaperone Hsp90, we show that the mean non-equilibrium work computed in an ensemble of trajectories of enforced ligand unbinding is a promising predictor for ligand unbinding rates.	Nitrogen	158-159	sepiapterin reductase	Homo sapiens	52-55
28630087-0	2017	Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions.	Nitrogen	18-19	elastase, neutrophil expressed	Homo sapiens	70-89
28630087-1	2017	Human neutrophil elastase (HNE) is an important N-glycosylated serine protease in the innate immune system, but the structure and immune-modulating functions of HNE N-glycosylation remain undescribed.	Nitrogen	28-29	elastase, neutrophil expressed	Homo sapiens	6-25
28630087-2	2017	Herein, LC-MS/MS-based glycan, glycopeptide and glycoprotein profiling were utilized to first determine the heterogeneous N-glycosylation of HNE purified from neutrophil lysates and then from isolated neutrophil granules of healthy individuals.	Nitrogen	122-123	elastase, neutrophil expressed	Homo sapiens	141-144
28630087-8	2017	Subcellular- and site-specific glycoprofiling showed highly uniform N-glycosylation of HNE residing in distinct neutrophil compartments.	Nitrogen	68-69	elastase, neutrophil expressed	Homo sapiens	87-90
29310259-6	2018	In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP.	Nitrogen	53-61	glycine decarboxylase	Homo sapiens	89-92
29310259-6	2018	In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP.	Nitrogen	53-61	glycine decarboxylase	Homo sapiens	89-92
29310259-6	2018	In comparison with glassy carbon electrode (GCE) and nitrogen-doped carbon (NC) modified GCE, the CoxP/NC modified GCE (CoxP/NC/GCE) showed a remarkable increase in DPV current toward 4-NP.	Nitrogen	53-61	glycine decarboxylase	Homo sapiens	120-131
29065215-7	2018	Gene expression experiments showed that, apart from the conventional nitrogen catabolic repression mechanism that is operating in aerobiosis, there seems to be an oxygen-independent mechanism acting to overexpress key genes like GAP1, GDH1, GDH2 and GLT1 to ensure adequate anaerobic growth even in the presence of non-preferential nitrogen source.	Nitrogen	332-340	glutamate synthase (NADH)	Saccharomyces cerevisiae S288C	250-254
29964843-2	2018	The results showed that:(1)The total runoff loss was 50.92x104 m3 in this watershed during the rainy season, with 52.43 kg hm-2 lost by total nitrogen, including nitrate nitrogen (30.26 kg hm-2) and particulate nitrogen (21.61 kg hm-2), and 0.06 kg hm-2 and 0.10 kg hm-2 lost by ammonium nitrogen and total phosphorus; (2)The distribution of rainfall has the characteristics of stage and strong rainfall during the wet season was the main driving force of soil nutrient output.	Nitrogen	142-150	cholinergic receptor muscarinic 2	Homo sapiens	123-127
28630087-12	2017	The heavily N-glycosylated HNE protease inhibitor, alpha1-antitrypsin, displayed concentration-dependent complex formation and preferred glycoform-glycoform interactions with HNE.	Nitrogen	12-13	elastase, neutrophil expressed	Homo sapiens	27-30
31828746-0	2019	Inhibition of NR2B-containing NMDA receptors during nitrogen narcosis.	Nitrogen	52-60	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	14-18
28676225-1	2017	Cytidine triphosphate synthase 1 (CTPS1) is an enzyme expressed in activated lymphocytes that catalyzes the conversion of uridine triphosphate (UTP) to cytidine triphosphate (CTP) with ATP-dependent amination, using either L-glutamine or ammonia as the nitrogen source.	Nitrogen	253-261	CTP synthase 1	Homo sapiens	0-32
28676225-1	2017	Cytidine triphosphate synthase 1 (CTPS1) is an enzyme expressed in activated lymphocytes that catalyzes the conversion of uridine triphosphate (UTP) to cytidine triphosphate (CTP) with ATP-dependent amination, using either L-glutamine or ammonia as the nitrogen source.	Nitrogen	253-261	CTP synthase 1	Homo sapiens	34-39
29273683-5	2018	We now show that mutations of conserved N-glycosylation sites at N238 in human CBG and N230 in rat CBG disrupt steroid binding.	Nitrogen	40-41	serpin family A member 6	Rattus norvegicus	99-102
31828746-8	2019	CONCLUSIONS: Our findings indicated that NR2B-containing NMDA receptors were inhibited during nitrogen narcosis.	Nitrogen	94-102	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	41-45
31857626-4	2019	In an angiotensin II (Ang II)-induced renal injury mouse model, we found that blocking AT1R and AT2R effectively mitigates Ang II-induced increases in necroptotic tubular epithelial cell percentages, necroptosis-related RIP3 and MLKL protein expression, serum creatinine and blood urea nitrogen levels, and tubular damage scores.	Nitrogen	286-294	angiotensin II receptor, type 2	Mus musculus	96-100
29299581-4	2018	The negative charge of {SnIVCl2(Pc 3-)} - is delocalized over the Pc macrocycle providing the alternation of the C-N(imine) bonds, the appearance of new bands in the NIR range and a strong blue shift of both the Soret and Q-bands in the spectrum of 1.	Nitrogen	115-116	keratin 6A	Homo sapiens	32-36
28561310-1	2017	Five new compounds comprised of unprecedented boron-nitrogen heterocycles have been isolated from a single reaction of a potentially tetradentate N2 O23- formazanate ligand with BF3  OEt2 and NEt3 .	Nitrogen	52-60	tetraspanin 2	Homo sapiens	192-196
31444548-7	2019	Somatic loss-of-function variants in the N-glycosylation pathway-associated SLC35A2 gene were found in mMCD/FCD1 cases.	Nitrogen	41-42	solute carrier family 35 member A2	Homo sapiens	76-83
28608694-3	2017	Each of the four models has an intramolecular nitrogen base that axially binds the iron(II) cation inside the porphyrin, but they differ either by the nature of the distal strap or by its mobility.	Nitrogen	46-54	serine/threonine kinase receptor associated protein	Homo sapiens	172-177
31444548-7	2019	Somatic loss-of-function variants in the N-glycosylation pathway-associated SLC35A2 gene were found in mMCD/FCD1 cases.	Nitrogen	41-42	malonyl-CoA decarboxylase	Mus musculus	103-107
29410661-9	2018	Nitrogen metabolism genes, in particular glutamate dehydrogenase (EC:1.4.1.4), glutamine synthetase (EC:6.3.1.2) and glutamate synthase (EC:1.4.1.13, EC:1.4.1.14) were also found to be highly expressed and prove rumen wall microbiota to be actively involved in providing host-relevant metabolites for exchange across the rumen wall.	Nitrogen	0-8	glutamate-ammonia ligase	Bos taurus	79-99
31471298-9	2019	CONCLUSION: Our observations indicate that somatic hypermutation of ACPA, which results in the incorporation of N-linked glycosylation sites and consequently V-domain glycans, occurs already years before symptom onset in individuals that will develop RA later in life.	Nitrogen	2-3	proteinase 3	Homo sapiens	68-72
29030255-9	2018	Three potential N-linked glycosylation sites and two cysteine residues (Cys-28 and Cys-209) that are likely to form one disulfide bond were present in pufferfish CA VI.	Nitrogen	16-17	carbonic anhydrase 6	Homo sapiens	162-167
28512031-3	2017	Replacing this with a C-N bond significantly simplified synthesis, yielding pyrazole analog 35, of which we obtained a co-crystal structure with KDM5A.	Nitrogen	24-25	lysine (K)-specific demethylase 5A	Mus musculus	145-150
31807193-5	2019	No prior association has been reported between adenomatosis polyposis coli 2 (APC2), homeobox A9, Wnt family member 7A (WNT7A) and N-Myc downstream-regulated gene 4 protein genes with PCa.	Nitrogen	0-1	APC regulator of WNT signaling pathway 2	Homo sapiens	47-76
28800566-1	2018	Cu(I) species were successfully chelated to nitrogen atoms in a nitrogen-rich porous organic polymer (SNW-1) by mixing with a CuCl solution (Scheme 1).	Nitrogen	44-52	SNW domain containing 1	Homo sapiens	102-107
28800566-1	2018	Cu(I) species were successfully chelated to nitrogen atoms in a nitrogen-rich porous organic polymer (SNW-1) by mixing with a CuCl solution (Scheme 1).	Nitrogen	64-72	SNW domain containing 1	Homo sapiens	102-107
31807193-5	2019	No prior association has been reported between adenomatosis polyposis coli 2 (APC2), homeobox A9, Wnt family member 7A (WNT7A) and N-Myc downstream-regulated gene 4 protein genes with PCa.	Nitrogen	0-1	APC regulator of WNT signaling pathway 2	Homo sapiens	78-82
31807193-5	2019	No prior association has been reported between adenomatosis polyposis coli 2 (APC2), homeobox A9, Wnt family member 7A (WNT7A) and N-Myc downstream-regulated gene 4 protein genes with PCa.	Nitrogen	0-1	homeobox A9	Homo sapiens	85-96
31671317-9	2019	Antibody array and immunoblotting analysis revealed that Indox inhibited the phosphorylation of multiple molecules, including key upstream proteins of MMP-9 in RAF/extracellular signal-regulated kinase (ERK), AKT, and stress-activated protein kinase/c-Jun-N-terminal kinase (SAPK/JNK) pathways.	Nitrogen	256-257	matrix metallopeptidase 9	Mus musculus	151-156
29113017-5	2018	Nitrogen addition at low rates (30 and 60 kg N ha-1  yr-1 ) took longer (e.g., three years or more) to achieve significant effects.	Nitrogen	0-8	solute carrier family 9 member B1	Homo sapiens	45-57
31694050-8	2019	Considering the above data of overlapping peptides of PC6 and PC7, N-terminal part of the PC7 peptide (DEVQRMM) is found to play a crucial role in Sorghum Polcalcin allergenic response.	Nitrogen	67-68	proprotein convertase subtilisin/kexin type 7	Mus musculus	62-65
29576721-0	2018	Comparative molecular field analysis and molecular dynamics studies of the dopamine D2 receptor antagonists without a protonatable nitrogen atom.	Nitrogen	131-139	dopamine receptor D2	Homo sapiens	75-95
31694050-8	2019	Considering the above data of overlapping peptides of PC6 and PC7, N-terminal part of the PC7 peptide (DEVQRMM) is found to play a crucial role in Sorghum Polcalcin allergenic response.	Nitrogen	67-68	proprotein convertase subtilisin/kexin type 7	Mus musculus	90-93
29172553-2	2017	A combination of site-selective N,N-di-Boc-activation (tert-butoxycarbonyl activation) of the amide nitrogen with practical air- and moisture-stable, well-defined, and highly reactive [Pd(NHC)(cin)Cl] (NHC = N-heterocyclic carbene; cin = cinnamyl) provides a highly effective route to biaryl ketones from primary amides in high yields.	Nitrogen	100-108	pyridoxal phosphatase	Homo sapiens	193-196
29172553-2	2017	A combination of site-selective N,N-di-Boc-activation (tert-butoxycarbonyl activation) of the amide nitrogen with practical air- and moisture-stable, well-defined, and highly reactive [Pd(NHC)(cin)Cl] (NHC = N-heterocyclic carbene; cin = cinnamyl) provides a highly effective route to biaryl ketones from primary amides in high yields.	Nitrogen	100-108	pyridoxal phosphatase	Homo sapiens	232-235
31795436-3	2019	Gelatinase A has no known physiological function in muscle cells, and its localization within mammalian cells appears to be due to inefficient recognition of its N-terminal secretory signal.	Nitrogen	162-163	matrix metallopeptidase 2	Danio rerio	0-12
29203835-5	2017	Glycosylation analysis revealed that AQP7 and 12 were O-glycosylated, AQP10 was N-glycosylated while the other AQPs were not glycosylated.	Nitrogen	80-81	aquaporin 10	Homo sapiens	70-75
31795436-5	2019	The N-terminal secretory signal of zebrafish Mmp2 is also challenging to identify, and this is a conserved characteristic of gelatinase A orthologues, suggesting a selective pressure acting to prevent the efficient secretion of this protease.	Nitrogen	4-5	matrix metallopeptidase 2	Danio rerio	45-49
31795436-5	2019	The N-terminal secretory signal of zebrafish Mmp2 is also challenging to identify, and this is a conserved characteristic of gelatinase A orthologues, suggesting a selective pressure acting to prevent the efficient secretion of this protease.	Nitrogen	4-5	matrix metallopeptidase 2	Danio rerio	125-137
29259722-8	2017	Results: hLYPD8 was a highly N-glycosylated GPI-anchored protein, like mLypd8.	Nitrogen	29-30	LY6/PLAUR domain containing 8	Mus musculus	71-77
31776360-4	2019	The mechanism involves signaling by mitochondria-generated H2O2 (mH2O2) acting via the redox sensor, peroxiredoxin-1, a thiol peroxidase with high reactivity towards H2O2 that activates c-Jun N-terminal kinase-2alpha2 (JNK2alpha2).	Nitrogen	192-193	jun proto-oncogene	Mus musculus	186-191
28844150-7	2017	Western blotting of key enzymes that metabolize glutamine revealed marked differences in the expression of glutaminase isoforms, KGA and CAG, as well as the PPAT enzyme that targets glutamine-derived nitrogen toward nucleotide synthesis.	Nitrogen	200-208	phosphoribosyl pyrophosphate amidotransferase	Homo sapiens	157-161
31751425-4	2019	Similar experiments with FMNL3 demonstrated that N-myristoylation-dependent phosphorylation occurs at a single Ser residue at position 174, which is a Ser residue conserved between FMNL2 and FMNL3, corresponding to Ser-171 in FMNL2.	Nitrogen	27-28	formin like 3	Homo sapiens	191-196
31839826-6	2019	Moreover, serum CCL18 level was significantly associated with primary tumor site (Glottic vs Others), T classification (T1+T2 vs T3+T4), clinical stage (I+II vs III+IV) and lymph node metastasis (N0 vs N+).	Nitrogen	202-204	C-C motif chemokine ligand 18	Homo sapiens	16-21
29162059-4	2017	In rice, studies on miR159 were either based upon genome-wide expression analyses focused upon responses to different nitrogen forms and abiotic stress or upon phenotypic studies of transgenic plants overexpressing its precursor.	Nitrogen	118-126	MIR159a	Arabidopsis thaliana	20-26
31710640-3	2019	Here, we report that the ubiquitin deconjugase encoded in the N-terminus of the Epstein-Barr virus (EBV) large tegument protein BPLF1 harnesses 14-3-3 molecules to promote TRIM25 autoubiquitination and sequestration of the ligase into inactive protein aggregates.	Nitrogen	62-63	tripartite motif containing 25	Homo sapiens	172-178
28419749-0	2017	Novel 19 F-MRS beta-galactosidase reporter molecules incorporated nitrogen mustard analogues.	Nitrogen	66-74	galactosidase beta 1	Homo sapiens	15-33
28419749-1	2017	In this study, we propose a novel molecular platform-integrated fluorinated antitumor nitrogen mustards for 19 F-MRS assay of beta-galactosidase (beta-gal) activity.	Nitrogen	86-94	galactosidase beta 1	Homo sapiens	126-144
28419749-1	2017	In this study, we propose a novel molecular platform-integrated fluorinated antitumor nitrogen mustards for 19 F-MRS assay of beta-galactosidase (beta-gal) activity.	Nitrogen	86-94	galactosidase beta 1	Homo sapiens	126-134
31878368-6	2019	CARS performances are reported for N2 thermometry between 300 K and 3000 K, demonstrating state of the art precision.	Nitrogen	35-37	cysteinyl-tRNA synthetase 1	Homo sapiens	0-4
28597972-7	2017	However, the glycosylation and function of mutant GLP-1R, in which all three sites for N-linked glycosylation were mutated, were not increased with overexpression of SERP1.	Nitrogen	87-88	glucagon like peptide 1 receptor	Homo sapiens	50-56
29058647-5	2017	We found that Gat1 plays an important role in the induction of UGA4 transcription by GABA and that Gzf3 has an effect in cells grown in a poor nitrogen source such as proline and that this effect is positive on UGA4 expression.	Nitrogen	143-151	Gzf3p	Saccharomyces cerevisiae S288C	99-103
31717991-8	2019	The N-terminal domain of the capsid protein was found to be responsible for the inhibition of IRF3 activation.	Nitrogen	4-5	interferon regulatory factor 3	Homo sapiens	94-98
31717991-9	2019	Further study showed that the arginine-rich-motif in the N-terminal domain is indispensable for the inhibition as mutations of any of the arginine residues abolished the blockage of IRF3 phosphorylation.	Nitrogen	57-58	interferon regulatory factor 3	Homo sapiens	182-186
31570524-7	2019	In summary, our results suggest a role for the C-terminal dimerization domain of MUC5B in compaction of mucin chains during granular packaging via interactions with the N-terminal multimerization domain.	Nitrogen	169-170	mucin 5B, oligomeric mucus/gel-forming	Homo sapiens	81-86
28811146-1	2017	The carbon-nitrogen ratio (COD/NH4+-N) is an important factor affecting nitrification and denitrification in wastewater treatment; this factor also influences nitrous oxide (N2O) emissions.	Nitrogen	11-19	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	27-30
31570524-7	2019	In summary, our results suggest a role for the C-terminal dimerization domain of MUC5B in compaction of mucin chains during granular packaging via interactions with the N-terminal multimerization domain.	Nitrogen	169-170	LOC100508689	Homo sapiens	104-109
31408776-10	2019	The increased N-containing heterocycles of CFCP accounted for the increased Cd2+ and Pb2+ adsorption.	Nitrogen	14-15	CD2 molecule	Gallus gallus	76-79
29109806-3	2017	As the N/Ga flux ratio decreased by increasing Ga flux, the GaN surface trended to a flat morphology with stripes along [11[Formula: see text]0].	Nitrogen	7-8	gigaxonin	Homo sapiens	60-63
31469196-5	2019	An interaction between dietary CP and TA on the urinary N excretion (p < .05) was found but not on the N2 O-N emission of cattle urine.	Nitrogen	56-57	ceruloplasmin	Bos taurus	31-33
28802165-3	2017	We conclude that the GARP family may hold keys to understand the interactions between nutritional signaling pathways (nitrogen and phosphate at least) and development.	Nitrogen	118-126	cyclic nucleotide gated channel subunit beta 1	Homo sapiens	21-25
28315854-6	2017	We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3beta/beta-catenin signaling pathway, which further adjusted MMP2/9 expression and activities.	Nitrogen	29-30	protein tyrosine kinase 2	Homo sapiens	89-92
28315854-6	2017	We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3beta/beta-catenin signaling pathway, which further adjusted MMP2/9 expression and activities.	Nitrogen	29-30	glycogen synthase kinase 3 beta	Homo sapiens	97-106
28315854-6	2017	We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3beta/beta-catenin signaling pathway, which further adjusted MMP2/9 expression and activities.	Nitrogen	29-30	matrix metallopeptidase 2	Homo sapiens	162-168
28945799-11	2017	Moreover, the absence of A/N-InvH prevented ROS formation, not only in invh roots of salt- and ABA-treated seedlings but also in invh control roots.	Nitrogen	27-28	invertase H	Arabidopsis thaliana	29-33
28945799-11	2017	Moreover, the absence of A/N-InvH prevented ROS formation, not only in invh roots of salt- and ABA-treated seedlings but also in invh control roots.	Nitrogen	27-28	invertase H	Arabidopsis thaliana	71-75
28945799-11	2017	Moreover, the absence of A/N-InvH prevented ROS formation, not only in invh roots of salt- and ABA-treated seedlings but also in invh control roots.	Nitrogen	27-28	invertase H	Arabidopsis thaliana	129-133
31469196-6	2019	Increasing dietary CP level from 110.6 g/kg DM to 135.7 g/kg DM increased the total N excretion (p < .001), the N retention (p < .05) and the ratio of urinary urea-N/urinary N (p < .01), did not affect the N use efficiency (NUE; p > .05) and shifted the N excretion from faeces to urine.	Nitrogen	84-85	ceruloplasmin	Bos taurus	19-21
29156678-4	2017	TUSC3 is a subunit of the oligosaccharyltransferase (OST) complex at the endoplasmic reticulum (ER) which catalyzes bulk N-glycosylation of membrane and secretory proteins.	Nitrogen	121-122	tumor suppressor candidate 3	Homo sapiens	0-5
31469196-6	2019	Increasing dietary CP level from 110.6 g/kg DM to 135.7 g/kg DM increased the total N excretion (p < .001), the N retention (p < .05) and the ratio of urinary urea-N/urinary N (p < .01), did not affect the N use efficiency (NUE; p > .05) and shifted the N excretion from faeces to urine.	Nitrogen	112-113	ceruloplasmin	Bos taurus	19-21
31469196-6	2019	Increasing dietary CP level from 110.6 g/kg DM to 135.7 g/kg DM increased the total N excretion (p < .001), the N retention (p < .05) and the ratio of urinary urea-N/urinary N (p < .01), did not affect the N use efficiency (NUE; p > .05) and shifted the N excretion from faeces to urine.	Nitrogen	112-113	ceruloplasmin	Bos taurus	19-21
28780317-4	2017	The isolated alphaR1P was N-glycosylated with different nitrogen bases (adenine, guanine and uracil) using PNPase or uridine phosphorylase (UPase) to give the corresponding ribonucleosides in high yield based on the glycosyl phosphate.	Nitrogen	26-27	uridine phosphorylase 1	Homo sapiens	140-145
28004495-2	2017	The modified NFGAIL with double N-methylated at Gly24 and Ile26 has the property of soluble, non-amyloidogenic, non-cytotoxic, and the ability of inhibiting amyloid formation and cytotoxicity of IAPP.	Nitrogen	13-14	islet amyloid polypeptide	Homo sapiens	195-199
31469196-6	2019	Increasing dietary CP level from 110.6 g/kg DM to 135.7 g/kg DM increased the total N excretion (p < .001), the N retention (p < .05) and the ratio of urinary urea-N/urinary N (p < .01), did not affect the N use efficiency (NUE; p > .05) and shifted the N excretion from faeces to urine.	Nitrogen	112-113	ceruloplasmin	Bos taurus	19-21
31469196-6	2019	Increasing dietary CP level from 110.6 g/kg DM to 135.7 g/kg DM increased the total N excretion (p < .001), the N retention (p < .05) and the ratio of urinary urea-N/urinary N (p < .01), did not affect the N use efficiency (NUE; p > .05) and shifted the N excretion from faeces to urine.	Nitrogen	112-113	ceruloplasmin	Bos taurus	19-21
31469196-6	2019	Increasing dietary CP level from 110.6 g/kg DM to 135.7 g/kg DM increased the total N excretion (p < .001), the N retention (p < .05) and the ratio of urinary urea-N/urinary N (p < .01), did not affect the N use efficiency (NUE; p > .05) and shifted the N excretion from faeces to urine.	Nitrogen	112-113	ceruloplasmin	Bos taurus	19-21
31469196-7	2019	Increasing the dietary CP level increased the N2 O-N emission of cattle urine.	Nitrogen	46-47	ceruloplasmin	Bos taurus	23-25
28337806-2	2017	The antiresorptive potency of the nitrogen-containing bisphosphonates on bone in vivo is now recognized to depend upon two key properties, namely mineral binding affinity and inhibitory activity on farnesyl pyrophosphate synthase (FPPS), and these properties vary independently of each other in individual bisphosphonates.	Nitrogen	34-42	farnesyl diphosphate synthase	Rattus norvegicus	198-229
28337806-2	2017	The antiresorptive potency of the nitrogen-containing bisphosphonates on bone in vivo is now recognized to depend upon two key properties, namely mineral binding affinity and inhibitory activity on farnesyl pyrophosphate synthase (FPPS), and these properties vary independently of each other in individual bisphosphonates.	Nitrogen	34-42	farnesyl diphosphate synthase	Rattus norvegicus	231-235
28554556-3	2017	A 365-fold increase (365.4 +- 65.0, P = 0.0001) in urinary N-ter titin excretion was seen in Duchene muscular dystrophy (DMD) patients.	Nitrogen	59-60	titin	Homo sapiens	65-70
31695625-6	2019	Using coimmunoprecipitation, we confirmed the physical interaction between ITM2B or TMEM85 and N-terminal GLUT9 isoforms (GLUT9a and GLUT9b) in transfected HEK 293T cells and Xenopus oocytes, wherein ITM2B but not TMEM85 inhibited GLUT9-mediated urate uptake.	Nitrogen	95-96	integral membrane protein 2B L homeolog	Xenopus laevis	200-205
31626627-7	2019	Genetic analysis revealed that the function of XTH9 was dependent on auxin-mediated ARF7/19 and downstream AFB3 in response to nitrogen signals.	Nitrogen	127-135	Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-like protein	Arabidopsis thaliana	84-88
28640838-6	2017	Furthermore, we identified N-glycosylation motifs characteristic for FL in the CDR3 region.	Nitrogen	27-28	CDR3	Homo sapiens	79-83
28794951-5	2017	The results showed that the triazine-based polymer HCP-1 had the highest CO2 over N2 selectivity of 75.4 at 295 K and 0.1 MPa, which makes it the most potential candidate for CO2 capture.	Nitrogen	82-84	CYCS pseudogene 51	Homo sapiens	51-56
28388573-6	2017	What is more, when detect the function of alphaMSH in ROS-induced apoptosis, similar inhibitory trend was found with the oxidative stress inhibitor N-acetyl-L-cysteine (NAC) in ROS-induced adipocyte apoptosis and this trend is alphaMSH receptor melanocortin 5 receptor (MC5R) depended, while an opposite trend was found between alphaMSH and Foxo1, which is a known positive regulator of adipocyte apoptosis.	Nitrogen	148-149	pro-opiomelanocortin-alpha	Mus musculus	42-50
28388573-6	2017	What is more, when detect the function of alphaMSH in ROS-induced apoptosis, similar inhibitory trend was found with the oxidative stress inhibitor N-acetyl-L-cysteine (NAC) in ROS-induced adipocyte apoptosis and this trend is alphaMSH receptor melanocortin 5 receptor (MC5R) depended, while an opposite trend was found between alphaMSH and Foxo1, which is a known positive regulator of adipocyte apoptosis.	Nitrogen	148-149	pro-opiomelanocortin-alpha	Mus musculus	227-235
28388573-6	2017	What is more, when detect the function of alphaMSH in ROS-induced apoptosis, similar inhibitory trend was found with the oxidative stress inhibitor N-acetyl-L-cysteine (NAC) in ROS-induced adipocyte apoptosis and this trend is alphaMSH receptor melanocortin 5 receptor (MC5R) depended, while an opposite trend was found between alphaMSH and Foxo1, which is a known positive regulator of adipocyte apoptosis.	Nitrogen	148-149	melanocortin 5 receptor	Mus musculus	245-268
28388573-6	2017	What is more, when detect the function of alphaMSH in ROS-induced apoptosis, similar inhibitory trend was found with the oxidative stress inhibitor N-acetyl-L-cysteine (NAC) in ROS-induced adipocyte apoptosis and this trend is alphaMSH receptor melanocortin 5 receptor (MC5R) depended, while an opposite trend was found between alphaMSH and Foxo1, which is a known positive regulator of adipocyte apoptosis.	Nitrogen	148-149	melanocortin 5 receptor	Mus musculus	270-274
28388573-6	2017	What is more, when detect the function of alphaMSH in ROS-induced apoptosis, similar inhibitory trend was found with the oxidative stress inhibitor N-acetyl-L-cysteine (NAC) in ROS-induced adipocyte apoptosis and this trend is alphaMSH receptor melanocortin 5 receptor (MC5R) depended, while an opposite trend was found between alphaMSH and Foxo1, which is a known positive regulator of adipocyte apoptosis.	Nitrogen	148-149	pro-opiomelanocortin-alpha	Mus musculus	227-235
28465474-4	2017	Mice were subjected to renal ischemia for 30 min followed by reperfusion for 24 h. The results showed that Res-DAP5-NP could decreased serum creatinine (Cr) and urea nitrogen (BUN), alleviated tubular damage and oxidative stress.	Nitrogen	166-174	eukaryotic translation initiation factor 4, gamma 2	Mus musculus	111-115
28370525-3	2017	The phase transition of butyl-SBP consists of a spin transition of the constituent pi dimers coupled with an order-disorder transition involving the butyl chains linked to the nitrogen atoms of the superimposed phenalenyl rings of the pi dimer.	Nitrogen	176-184	selenium binding protein 1	Homo sapiens	30-33
28414434-5	2017	Significantly, the weakened N-H bonds in (iPrPDI)Mo(NH3)2(eta2-C2H4) enabled hydrogen atom abstraction and synthesis of a terminal nitride from coordinated ammonia, a key step in NH3 oxidation.	Nitrogen	28-29	DNA polymerase iota	Homo sapiens	58-62
28232482-3	2017	In aspartate aminotransferase (AAT), an extended hydrogen bond network is coupled to the pyridinyl nitrogen of the PLP, influencing the electrophilicity of the cofactor.	Nitrogen	99-107	pyridoxal phosphatase	Homo sapiens	115-118
28232482-5	2017	We demonstrate that this hydrogen bond network directly influences the protonation state of the pyridine nitrogen of PLP, which affects the rates of catalysis.	Nitrogen	105-113	pyridoxal phosphatase	Homo sapiens	117-120
28232482-8	2017	Thus, PLP activation is controlled by the proximity of the pyridinyl nitrogen to the hydrogen bond microenvironment.	Nitrogen	69-77	pyridoxal phosphatase	Homo sapiens	6-9
28111287-0	2017	Arabidopsis CBL-Interacting Protein Kinases Regulate Carbon/Nitrogen-Nutrient Response by Phosphorylating Ubiquitin Ligase ATL31.	Nitrogen	60-68	carbon/nitrogen insensitive 1	Arabidopsis thaliana	123-128
28352079-5	2017	Following administration of LPS, pod-Shp2 KO mice exhibited lower proteinuria and blood urea nitrogen concentrations than controls indicative of preserved filter integrity.	Nitrogen	93-101	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	37-41
27690717-3	2017	Using a combination of site-directed mutagenesis, western blot and patch-clamp recordings, we demonstrated that 3 sites in the extracellular loop of beta2 subunit are N-glycosylated (N-X-T/S at N88, N96 and N119).	Nitrogen	167-168	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	149-154
27690717-6	2017	Our results suggest that N-glycosylation of beta2 subunits plays crucial roles in imparting functional heterogeneity of BK channels, and is potentially involved in the pathological phenotypes of carbohydrate metabolic diseases.	Nitrogen	25-26	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	44-49
27790922-2	2017	RESULTS: uromodulin predicted GL equivalently to the other markers studied: the risk for GL was reduced by 0.21 per one standard deviation (SD) increase (cystatin C: hazard ratio [HR] 4.57, creatinine: HR 4.53, blood-urea-nitrogen [BUN]: HR 2.50, estimated glomerular filtration rate [eGFR]: HR 0.10).	Nitrogen	222-230	cystatin C	Homo sapiens	154-164
28186505-0	2017	N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death.	Nitrogen	0-1	TNF receptor superfamily member 10a	Homo sapiens	43-51
28186505-2	2017	We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans.	Nitrogen	25-26	tumor necrosis factor receptor superfamily, member 10b	Mus musculus	187-195
28186505-2	2017	We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans.	Nitrogen	49-50	tumor necrosis factor receptor superfamily, member 10b	Mus musculus	187-195
27943312-4	2017	Slopes of regressions between accumulation of 13 C-labelled carbon and 15 N-labelled N were higher for LHT1-overexpressing plants than wild type plants, while plants lacking expression of LHT1 did not display a significant regression between the two isotopes.	Nitrogen	74-75	lysine histidine transporter 1	Arabidopsis thaliana	103-107
27856053-2	2017	The characterization by XRD, SEM-EDX and BET-N2 adsorption demonstrated that Fe, Cu/Fe and Mn/Fe nano particles were successfully loaded onto NaY zeolite and exhibited larger BET surface area compared to nano-Fe0 (nZVI).	Nitrogen	45-47	delta/notch like EGF repeat containing	Homo sapiens	41-44
28106395-4	2017	Our studies show that steric effects of N-substituents of the isocyanides play an important role in the stability of the three-membered metallacycles of the eta2-iminoketenyl complexes.	Nitrogen	40-41	DNA polymerase iota	Homo sapiens	157-161
28220142-8	2017	Analysis of recombinant viruses containing amino acid substitutions selected at different mouse brain passages during the generation of Can revealed that altered Can GPC processing was primarily due to the T168A substitution within G1, which eliminates an N-linked glycosylation motif.	Nitrogen	256-257	glycoprotein precursor	Argentinian mammarenavirus	166-169
28220142-13	2017	Additionally, our findings indicate that the N-linked glycosylation motif at amino acid positions 166-168 is important for trafficking of JUNV GPC to the cell surface, and the elimination of this motif interferes with the GPC release from the ER.	Nitrogen	45-46	glycoprotein precursor	Argentinian mammarenavirus	143-146
28220142-13	2017	Additionally, our findings indicate that the N-linked glycosylation motif at amino acid positions 166-168 is important for trafficking of JUNV GPC to the cell surface, and the elimination of this motif interferes with the GPC release from the ER.	Nitrogen	45-46	glycoprotein precursor	Argentinian mammarenavirus	222-225
28084665-8	2017	Reducing cellular tRNA molecule desensitizes TORC1 inactivation by nitrogen starvation in vivo.	Nitrogen	67-75	CREB regulated transcription coactivator 1	Mus musculus	45-50
27908775-2	2017	General amino acid permease Gap1p is response of aromatic amino acids transportation, and GATA transcription factors Gln3p and Gat1p regulate the transcription of permease gene and catabolic enzyme genes for nitrogen sources and aromatic amino acids utilization.	Nitrogen	208-216	Gat1p	Saccharomyces cerevisiae S288C	127-132
27773655-8	2017	This stretch harbors a unique N-glycosylation site that is responsible for LPH retention in the ER via association with calnexin and facilitates proper folding of domains I and III before ER exit of LPH.	Nitrogen	30-31	lactase	Homo sapiens	75-78
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	33-41	proline permease PUT4	Saccharomyces cerevisiae S288C	100-104
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	33-41	Ptr2p	Saccharomyces cerevisiae S288C	122-126
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	83-91	proline permease PUT4	Saccharomyces cerevisiae S288C	100-104
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	83-91	Ptr2p	Saccharomyces cerevisiae S288C	122-126
28777557-11	2017	Strong interactions between Hg2+ and the nitrogen atoms of the tetrazine groups along with easy accessibility of Hg2+ to the tetrazine groups lead to a shorter response time (15 s) in comparison with other MOF-based Hg2+ sensors.	Nitrogen	41-49	lysine acetyltransferase 8	Homo sapiens	206-209
28576849-11	2017	Treatment with kifunensine, an inhibitor of complex-type N-glycosylation, weakened the binding of Gal-1 and Gal-3 to these interactors and prevented lattice formation.	Nitrogen	57-58	galectin 3	Homo sapiens	108-113
28857015-0	2017	N-glycosylation of the transient receptor potential melastatin 8 channel is altered in pancreatic cancer cells.	Nitrogen	0-1	transient receptor potential cation channel subfamily M member 8	Homo sapiens	23-64
28506525-5	2017	This, in conjunction with recently raised doubts regarding some of the Mg2+ assignments near the imino nitrogen of guanine, is suggestive of the existence of multiple Mg2+ binding modes for this basepair.	Nitrogen	103-111	mucin 7, secreted	Homo sapiens	167-170
28468779-3	2017	Known NAMPT inhibitors with potent cell activity are composed of a nitrogen-containing aromatic group, which is phosphoribosylated by the enzyme.	Nitrogen	67-75	nicotinamide phosphoribosyltransferase	Homo sapiens	6-11
28468779-4	2017	Here, we identified two novel types of NAM-competitive NAMPT inhibitors, only one of which contains a modifiable, aromatic nitrogen that could be a phosphoribosyl acceptor.	Nitrogen	123-131	nicotinamide phosphoribosyltransferase	Homo sapiens	55-60
28483912-2	2017	In the yeast Saccharomyces cerevisiae, various nitrogen sources activate TORC1 with different efficiencies, although the mechanism remains elusive.	Nitrogen	47-55	CREB regulated transcription coactivator 1	Homo sapiens	73-78
28548833-1	2017	Nicotinamide N-methyltransferase (NNMT) is a fundamental cytosolic biotransforming enzyme that catalyzes the N-methylation of endogenous and exogenous xenobiotics.	Nitrogen	0-1	nicotinamide N-methyltransferase	Homo sapiens	34-38
28548833-3	2017	Screening of N-methylated quinolinium, isoquinolinium, pyrididium, and benzimidazolium/benzothiazolium analogues resulted in the identification of quinoliniums as a promising scaffold with very low micromolar (IC50 ~ 1 muM) NNMT inhibition.	Nitrogen	13-14	nicotinamide N-methyltransferase	Homo sapiens	224-228
29745153-8	2017	On the basis of the combined perspective of commercial melon yield, and nitrogen absorption and utilization rate, an applied nitrogen amount of 240 kg hm-2 is most suitable for graf-ting cultivation in this region.	Nitrogen	125-133	cholinergic receptor muscarinic 2	Homo sapiens	151-155
28592651-8	2017	Based on these approaches, we were able to validate ARO1, PDC1, CPS1, ASI2, LYP1, and ALP1 allelic variants underlying nitrogen consumption differences between strains, providing evidence of many genes with small phenotypic effects.	Nitrogen	119-127	lysine permease	Saccharomyces cerevisiae S288C	76-80
28497772-4	2017	The modification of Fe-incorporated nitrogen-rich-carbons (Fe-CNx) on CNTs lowers the ORR half-wave-potential by ~190 mV, giving this catalyst with an onset ORR potential of 0.95 V (versus reversible hydrogen electrode (RHE)), a half-wave potential of 0.82 V (versus RHE), and the limiting current density of 5.39 mA cm-2 in 0.1 M KOH.	Nitrogen	36-44	calnexin	Homo sapiens	62-65
28919700-5	2017	Coil 2 will be constructed in the following sequence: 1) after winding each DP will be individually tested in a bath of liquid nitrogen at atmospheric pressure to determine its current carrying capabilities; 2) DPs will be then assembled as a stack with interconnecting joints, and 3) as in Coil 1, each pancake will be overbanded with a stainless steel tape, this time to a thickness of 5 mm, thickness determined by a stress analysis previously performed.	Nitrogen	127-135	coilin	Homo sapiens	0-4
28919700-6	2017	Finally the fully assembled Coil 2 will be tested in liquid nitrogen at 77 K and then in liquid helium at 4.2 K. We present here details of the stress analysis leading to the sizing of the DP inner supporting stainless steel ring and of the overbanding thickness required.	Nitrogen	60-68	coilin	Homo sapiens	28-32
28620376-0	2017	The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains.	Nitrogen	4-5	immunoglobulin heavy chain (V7183 family)	Mus musculus	29-45
28620376-0	2017	The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains.	Nitrogen	4-5	immunoglobulin heavy chain (V7183 family)	Mus musculus	47-50
28620376-0	2017	The N-Glycosylation of Mouse Immunoglobulin G (IgG)-Fragment Crystallizable Differs Between IgG Subclasses and Strains.	Nitrogen	4-5	immunoglobulin heavy chain (V7183 family)	Mus musculus	92-95
28620376-1	2017	N-linked glycosylation of the fragment crystallizable (Fc)-region of immunoglobulin G (IgG) is known to have a large influence on the activity of the antibody, an effect reported to be IgG subclass specific.	Nitrogen	0-1	immunoglobulin heavy chain (V7183 family)	Mus musculus	69-85
28620376-1	2017	N-linked glycosylation of the fragment crystallizable (Fc)-region of immunoglobulin G (IgG) is known to have a large influence on the activity of the antibody, an effect reported to be IgG subclass specific.	Nitrogen	0-1	immunoglobulin heavy chain (V7183 family)	Mus musculus	87-90
28620376-1	2017	N-linked glycosylation of the fragment crystallizable (Fc)-region of immunoglobulin G (IgG) is known to have a large influence on the activity of the antibody, an effect reported to be IgG subclass specific.	Nitrogen	0-1	immunoglobulin heavy chain (V7183 family)	Mus musculus	185-188
28542210-9	2017	In vitro, Pol theta can efficiently bypass a model unhooked nitrogen mustard crosslink and promote DNA synthesis following microhomology annealing, although ATPase activity is not required for these functions.	Nitrogen	60-68	DNA polymerase theta	Drosophila melanogaster	10-19
28513773-7	2017	Renal markers creatinine (Cr) and blood urea nitrogen (BUN) were significantly lower in the groups that received SAB.	Nitrogen	45-53	SH3-domain binding protein 5	Rattus norvegicus	113-116
28322516-2	2017	Herein, ZnO nanoparticles encapsulated into N-doped porous carbon has been rationally prepared by the pyrolysis of a metal-organic framework (MOF) followed by a moderate oxidation treatment.	Nitrogen	44-45	lysine acetyltransferase 8	Homo sapiens	117-146
28351617-0	2017	Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion.	Nitrogen	97-98	BMP/retinoic acid inducible neural specific 3	Homo sapiens	15-20
28351617-0	2017	Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion.	Nitrogen	97-98	BMP/retinoic acid inducible neural specific 3	Homo sapiens	116-121
28351617-6	2017	Molecular size of FAM5C was reduced by treatment with N-glycosidase F and in FAM5C-expressing cells cultured in the presence of the N-glycosylation inhibitor tunicamycin.	Nitrogen	54-55	BMP/retinoic acid inducible neural specific 3	Homo sapiens	18-23
28351617-9	2017	These results demonstrated that FAM5C is an N-glycosylated protein and N-glycosylation is necessary for the secretion of FAM5C.	Nitrogen	44-45	BMP/retinoic acid inducible neural specific 3	Homo sapiens	32-37
28360125-5	2017	Increased Grb2-NOX4 interactions play a preventive role against cytoskeletal disassembly, in turn blocking the activity of nitrogen oxides and decreasing the expression of slingshot homolog 1 (SSH-1) protein, a potent inducer of cytoskeleton disassembly.	Nitrogen	123-131	NADPH oxidase 4	Homo sapiens	15-19
28529777-2	2017	Reacting a dinuclear nitro-gen-bridged low-valent titanium(III) complex with the Lewis acids AlMe3 or GaMe3 results in the loss of mol-ecular di-nitro-gen and the formation of two monomeric titanocene(III) fragments bearing two mu2-bridging methyl groups.	Nitrogen	21-30	adaptor related protein complex 1 subunit mu 2	Homo sapiens	228-231
28413263-0	2017	Intensified Microwave-Assisted N-Acylation Procedure - Synthesis and Activity Evaluation of TRPC3 Channel Agonists with a 1,3-Dihydro-2H-benzo[d]imidazol-2-one Core.	Nitrogen	31-32	transient receptor potential cation channel subfamily C member 3	Homo sapiens	92-97
28723213-1	2017	A dual functional fluorescent core-shell Ag2S@Carbon nanostructure is prepared by a hydrothermally assisted multi-amino synthesis approach with folic acid (FA), polyethylenimine (PEI), and mannoses (Mans) as carbon and nitrogen sources (FA-PEI-Mans-Ag2S nanocomposite shortly as Ag2S@C).	Nitrogen	219-227	angiotensin II receptor type 1	Homo sapiens	41-45
27914709-7	2017	In contrast, transgenic CCR2 overexpression in the podocytes of Ccr2-/- mice resulted in significantly increased albuminuria, blood urea nitrogen, histopathologic changes, kidney fibronectin and type 1 collagen expression, podocyte loss, and glomerular apoptosis after nine weeks of streptozotocin-induced diabetes.	Nitrogen	137-145	chemokine (C-C motif) receptor 2	Mus musculus	24-28
28249157-0	2017	Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II.	Nitrogen	0-1	hydroxyacylglutathione hydrolase	Homo sapiens	133-146
28249157-6	2017	This suggests that the hitherto obscure role of Glo2 in mitochondria is to act upstream of Sirt3 in minimizing protein N-acetylation, thus limiting protein dysfunction when AcCoA accumulates.	Nitrogen	119-120	hydroxyacylglutathione hydrolase	Homo sapiens	48-52
28150736-10	2017	We also found trends of increasing blood urea nitrogen and serum creatinine levels with increased intensity of tubular B7-1 expression.	Nitrogen	46-54	CD80 molecule	Homo sapiens	119-123
27773655-8	2017	This stretch harbors a unique N-glycosylation site that is responsible for LPH retention in the ER via association with calnexin and facilitates proper folding of domains I and III before ER exit of LPH.	Nitrogen	30-31	calnexin	Homo sapiens	120-128
27773655-8	2017	This stretch harbors a unique N-glycosylation site that is responsible for LPH retention in the ER via association with calnexin and facilitates proper folding of domains I and III before ER exit of LPH.	Nitrogen	30-31	lactase	Homo sapiens	199-202
27773655-9	2017	Notably, a similar N-glycosylation site is also found in domain IV with comparable effects on the trafficking of LPH-derived molecules.	Nitrogen	0-1	lactase	Homo sapiens	113-116
28513288-5	2017	Gas6 was inversely correlated with BMI, WHR, and HbA1c, while cystatin C was inversely correlated with urea nitrogen and creatinine.	Nitrogen	108-116	cystatin C	Homo sapiens	62-72
28546823-0	2017	Study of Guanxinning Injection on Regulatory Mechanism of Bcl-2 and Bax by Liquid Nitrogen Freezing-Mediated Femoral Head Necrosis.	Nitrogen	82-90	apoptosis regulator BAX	Oryctolagus cuniculus	68-71
28546823-1	2017	The objective of this study was to investigate the impact of femoral head perfusion by traditional Chinese medicine Guanxinning injection promoting blood circulation for removing blood stasis on the expression of Bcl-2 and Bax induced by liquid nitrogen freezing-mediated femoral head necrosis.	Nitrogen	245-253	apoptosis regulator BAX	Oryctolagus cuniculus	223-226
29900035-5	2017	Five N-glycosylation sites were conserved for all mammalian ENPEP proteins examined although 9-18 sites were observed, in each case.	Nitrogen	5-6	glutamyl aminopeptidase	Homo sapiens	60-65
27787842-4	2017	A mutant mammalian cell line, HEK293S GnTI-, was used as an expression host for the production of a crystallizable-quality mPlxnA2 fragment, which contains several N-glycosylation sites and disulfide bonds.	Nitrogen	164-165	plexin A2	Mus musculus	123-130
28664184-3	2017	Our previous work showed that the SCAP/SREBP-1 pathway is significantly upregulated in human glioblastoma (GBM), the most deadly brain cancer, and that glucose-mediated N-glycosylation of SCAP is a prerequisite step for SCAP/SREBP trafficking.	Nitrogen	169-170	SREBF chaperone	Homo sapiens	34-38
27817114-0	2017	Nitrogen-containing bisphosphonate induces a newly discovered hematopoietic structure in the omentum of an anemic mouse model by stimulating G-CSF production.	Nitrogen	0-8	peripheral blood stem cell response to granulocyte colony stimulating factor 1	Mus musculus	141-146
28664184-3	2017	Our previous work showed that the SCAP/SREBP-1 pathway is significantly upregulated in human glioblastoma (GBM), the most deadly brain cancer, and that glucose-mediated N-glycosylation of SCAP is a prerequisite step for SCAP/SREBP trafficking.	Nitrogen	169-170	SREBF chaperone	Homo sapiens	188-192
31626627-8	2019	In addition, we identified another transcription factor, OBP4, that was also induced by nitrogen treatment, but the induction was much slower than that of XTH9.	Nitrogen	88-96	OBF binding protein 4	Arabidopsis thaliana	57-61
28664184-3	2017	Our previous work showed that the SCAP/SREBP-1 pathway is significantly upregulated in human glioblastoma (GBM), the most deadly brain cancer, and that glucose-mediated N-glycosylation of SCAP is a prerequisite step for SCAP/SREBP trafficking.	Nitrogen	169-170	SREBF chaperone	Homo sapiens	188-192
31339661-0	2019	MIL-53(Al) as a Versatile Platform for Ionic-Liquid/MOF Composites to Enhance CO2 Selectivity over CH4 and N2.	Nitrogen	107-109	lysine acetyltransferase 8	Homo sapiens	52-55
31613983-4	2019	Natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro B-type natriuretic peptide (NT-proBNP), are well-established biomarkers for the detection and diagnostic evaluation of heart failure.	Nitrogen	0-1	natriuretic peptide B	Homo sapiens	38-64
29749198-5	2017	The treatment of subsoiling tillage coupling with 225 kg hm-2 nitrogen, was best for soil nitrogen transformation while the treatment of subsoiling tillage coupling with 330 kg hm-2 nitrogen, had the highest corn yield.	Nitrogen	90-98	Putative anthocyanidin reductase	Zea mays	57-61
28194158-9	2017	Surprisingly, AcdS was shown to confer the ability to utilize formamide and some dipeptides as sole nitrogen source.	Nitrogen	100-108	1-aminocyclopropane-1-carboxylate deaminase	Sinorhizobium meliloti	14-18
27923930-0	2017	Mg2+ ions: do they bind to nucleobase nitrogens?	Nitrogen	38-47	mucin 7, secreted	Homo sapiens	0-3
27923930-5	2017	We report that Mg2+ assigned near imine nitrogens derive mostly from poor interpretations of electron density patterns and are most often misidentified Na+, K+, NH4+ ions, water molecules or spurious density peaks.	Nitrogen	40-49	mucin 7, secreted	Homo sapiens	15-18
31613983-4	2019	Natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro B-type natriuretic peptide (NT-proBNP), are well-established biomarkers for the detection and diagnostic evaluation of heart failure.	Nitrogen	0-1	natriuretic peptide B	Homo sapiens	66-69
27940912-8	2016	A primary intrinsic 13C KIE of 1.04, an inverse intrinsic alpha-secondary CD3 KIE of 0.90, and a small but statistically significant inverse CD3 BIE of 0.96, in combination with computational modeling, revealed that SET8-catalyzed methylation proceeds through an early, asymmetrical SN2 transition state with the C-N and C-S distances of 2.35-2.40 A and 2.00-2.05 A, respectively.	Nitrogen	284-285	lysine methyltransferase 5A	Homo sapiens	216-220
31613983-4	2019	Natriuretic peptides (NPs), including B-type natriuretic peptide (BNP) and N-terminal pro B-type natriuretic peptide (NT-proBNP), are well-established biomarkers for the detection and diagnostic evaluation of heart failure.	Nitrogen	0-1	natriuretic peptide B	Homo sapiens	90-116
27956623-3	2016	By comparative gene expression profiling of p53-mutated and p53-depleted cancer cells, we identified ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a mutant p53 target gene, which functions as a uridine 5"-diphosphatase (UDPase) in the endoplasmic reticulum (ER) to promote the folding of N-glycosylated membrane proteins.	Nitrogen	152-153	ectonucleoside triphosphate diphosphohydrolase 5	Mus musculus	101-149
27839712-7	2016	BER is initiated by DNA N-glycosylases, such as S. cerevisiae Ntg1.	Nitrogen	21-22	bifunctional N-glycosylase/AP lyase NTG1	Saccharomyces cerevisiae S288C	62-66
28046067-5	2017	beta-glucuronidase (Gusb) was identified as a protein bound to Dectin-2 and mutations of N-glycosylation sites in Gusb impaired the binding of Gusb to Dectin-2.	Nitrogen	89-90	glucuronidase beta	Homo sapiens	0-18
28046067-5	2017	beta-glucuronidase (Gusb) was identified as a protein bound to Dectin-2 and mutations of N-glycosylation sites in Gusb impaired the binding of Gusb to Dectin-2.	Nitrogen	89-90	glucuronidase beta	Homo sapiens	20-24
28046067-5	2017	beta-glucuronidase (Gusb) was identified as a protein bound to Dectin-2 and mutations of N-glycosylation sites in Gusb impaired the binding of Gusb to Dectin-2.	Nitrogen	89-90	glucuronidase beta	Homo sapiens	114-118
28046067-5	2017	beta-glucuronidase (Gusb) was identified as a protein bound to Dectin-2 and mutations of N-glycosylation sites in Gusb impaired the binding of Gusb to Dectin-2.	Nitrogen	89-90	glucuronidase beta	Homo sapiens	114-118
31067000-3	2019	The corresponding N-glycosylation sites in ACPA V-region sequences result from somatic hypermutation, a T cell-dependent process.	Nitrogen	18-19	proteinase 3	Homo sapiens	43-47
27497618-7	2017	Serum TARC levels positively correlated with age, white blood cell (WBC) count, neutrophil count, eosinophil count, monocyte count, atypical lymphocyte (Aty-ly) count, serum blood urea nitrogen (BUN) levels, and creatinine (Cr) levels.	Nitrogen	185-193	C-C motif chemokine ligand 17	Homo sapiens	6-10
27737912-4	2016	Here, we show that in a distantly related fungal organism, the fission yeast Schizosaccharomyces pombe, autophagy of ER and mitochondria is induced by nitrogen starvation and is promoted by three Atg20- and Atg24-family proteins - Atg20, Atg24 and SPBC1711.11 (named here as Atg24b).	Nitrogen	151-159	Atg20p	Saccharomyces cerevisiae S288C	231-236
31375472-2	2019	The assay was created to develop physiologically relevant P450 inhibition information, taking advantage of the complete organelle composition and their associated drug-metabolizing enzymes of the MMHH but with the ease of use of human liver microsomes, including storage at -80 C instead of in liquid nitrogen, and thaw and use without centrifugation and microscopic evaluation as required for intact hepatocytes.	Nitrogen	301-309	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	58-62
27895582-0	2016	Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation.	Nitrogen	19-20	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	45-72
27745548-3	2017	Among patients with colon (19) and pancreatic tumors (40), 53 and 68 %, respectively, displayed T/N values &amp;gt;4 for CD suggesting chemotherapy with 5-FdC, 4-N-methylamino-5-FdC, 5-trifluoromethyldeoxycytidine and radiosensitization with 5- CldC, 4-N-methylamino-5-CldC, 5-iododeoxycytidine and 5-bromodeoxycytidine.	Nitrogen	98-99	cytidine deaminase	Homo sapiens	121-123
28251430-9	2017	Our study showed ATRX status to correlate with the T/N ratio and the outcomes of WHO grade II and III glioma patients with the IDH1 mutation.	Nitrogen	53-54	ATRX chromatin remodeler	Homo sapiens	17-21
31419031-0	2019	Amorphous Sn/Crystalline SnS2 Nanosheets via In Situ Electrochemical Reduction Methodology for Highly Efficient Ambient N2 Fixation.	Nitrogen	120-122	sodium voltage-gated channel alpha subunit 11	Homo sapiens	25-29
27560450-5	2016	Consistently, the inhibition of the Arg/N-end rule pathway with PCA significantly elevated levels of MAPT and huntingtin aggregates, accompanied by increased numbers of LC3 and SQSTM1 puncta.	Nitrogen	40-41	huntingtin	Homo sapiens	110-120
31575075-3	2019	We confirm that DDX3X nuclear export is mediated by the nuclear transporter exportin-1/CRM1, dependent on an N-terminal, leucine-rich nuclear export signal (NES) and the monomeric guanine nucleotide binding protein Ran in activated GTP-bound form.	Nitrogen	109-110	DEAD-box helicase 3 X-linked	Homo sapiens	16-21
27659162-5	2016	In the present study, we show that site-specific N-glycosylation of Cav3.2 is essential to stabilize expression of the channel at the plasma membrane.	Nitrogen	49-50	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	68-74
27659162-7	2016	Collectively, our study indicates that glucose and N-glycosylation act in concert to control the expression of Cav3.2 channels, and that alteration of these mechanisms may contribute to the altered expression of T-type channels in pathological conditions.	Nitrogen	51-52	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	111-117
27879192-5	2017	The BNP level was positively correlated with age, heart rate, creatinine kinase-myocardial band (CK-MB), cardiac troponin T (cTnT), and blood urea nitrogen (BUN), whereas it was negatively correlated with left ventricular ejection fraction (LVEF).	Nitrogen	147-155	natriuretic peptide B	Homo sapiens	4-7
31575168-8	2019	Using the overlapping qQ3(N = 4-9) transitions of HO2, we estimate limits of detection of 3.1 x 108 cm-3 based on traditional (absorption) CRDS methods and 6.7 x 107 cm-3 using FR-CRDS detection, where each point of the spectrum was acquired during 2 s. In addition, Verdet constants for pertinent carrier (He, Ar) and bulk (N2, O2) gases were recorded in this spectral region for the first time.	Nitrogen	325-327	heme oxygenase 2	Homo sapiens	50-53
27826240-4	2016	Majority of these compounds are nitrogen containing and belong to non-ribosomal peptide (NRPs) or mixed polyketide-NRP natural products.	Nitrogen	32-40	neuropilin 1	Homo sapiens	89-92
31558698-5	2019	This synergism is dependent on the presence of the N-terminal, NuRD-binding motif in ZNF521, and is sensitive to HDAC (histone deacetylase) and GLI inhibitors.	Nitrogen	51-52	zinc finger protein 521	Homo sapiens	85-91
31428786-0	2019	RNA degradomes reveal substrates and importance for dark and nitrogen stress responses of Arabidopsis XRN4.	Nitrogen	61-69	exoribonuclease 4	Arabidopsis thaliana	102-106
27711538-0	2016	Concerted nitrogen inversion and hydrogen bonding to Glu451 are responsible for protein-controlled suppression of the reverse reaction in human DPP III.	Nitrogen	10-18	dipeptidyl peptidase 3	Homo sapiens	144-151
31428786-5	2019	Among these XRN4 substrates that have 5" ends precisely at cap sites, those associated with photosynthesis, nitrogen responses and auxin responses were enriched.	Nitrogen	108-116	exoribonuclease 4	Arabidopsis thaliana	12-16
27570878-1	2016	Nicotinamide N-methyltransferase (NNMT) is one of the most abundant small molecule methyltransferases in the human body and is primarily responsible for the N-methylation of the nicotinamide (vitamin B3).	Nitrogen	0-1	nicotinamide N-methyltransferase	Homo sapiens	34-38
31554244-6	2019	Finally, we present preliminary data showing that the cytokine IL-6 cross talks with activation of the c-Jun N-terminal kinase pathway in response to heme-hemopexin in models of hepatocytes.	Nitrogen	109-110	hemopexin	Homo sapiens	155-164
27570878-2	2016	Employing the cofactor S-adenosyl-l-methionine, NNMT transfers a methyl group to the pyridine nitrogen of nicotinamide to generate N-methylnicotinamide.	Nitrogen	94-102	nicotinamide N-methyltransferase	Homo sapiens	48-52
27564678-3	2016	In this paper, nitrogen-doped conductive carbon/WS2 nanocomposites (WS2-NC) were fabricated based on the synthesis of the pure WS2 and conductive carbon/WS2 (WS2-C) nanocomposites.	Nitrogen	15-23	WS2C	Homo sapiens	158-163
27320963-4	2016	Its contribution to the in vivo hepatic net clearance of the N-oxygenation products was calculated by application of an extended relative activity factor (RAF) approach to differentiate from contribution of cytochrome P450 (CYP) isoforms.	Nitrogen	61-62	zinc fingers and homeoboxes 2	Homo sapiens	155-158
31616290-10	2019	SKA-111 (5-methylnaphtho[1,2-d]thiazol-2-amine) is binding in the interface between the CaM N-lobe and the S4-S5 linker where it makes van der Waals contacts with S181 and L185 in the S45A helix of KCa3.1.	Nitrogen	92-93	potassium calcium-activated channel subfamily N member 4	Homo sapiens	198-204
31620005-6	2019	C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P &lt; 0.01) at 175 mg kg-1 APAP dose, and phosphorylation levels of upstream proteins of JNK were also decreased markedly (P &lt; 0.05).	Nitrogen	6-7	jun proto-oncogene	Mus musculus	0-5
27493030-12	2016	The combined thermodynamic and spectroscopic approach allowed us to demonstrate that hIAPP is able to bind Cu(2+) ions starting from the His18 imidazole nitrogen atom toward the N-terminus domain.	Nitrogen	153-161	islet amyloid polypeptide	Homo sapiens	85-90
31620005-6	2019	C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P &lt; 0.01) at 175 mg kg-1 APAP dose, and phosphorylation levels of upstream proteins of JNK were also decreased markedly (P &lt; 0.05).	Nitrogen	6-7	jun proto-oncogene	Mus musculus	52-57
31216515-6	2019	The resultant membrane, the mica supported IL membrane (M-SILM), has about 80 GPU for CO2 permeance, and selectivity for CO2/H2, CO2/CH4 and CO2/N2 of 7.7, 28.6 and 87, respectively.	Nitrogen	145-147	MHC class I polypeptide-related sequence A	Homo sapiens	28-32
27518459-2	2016	This reaction proceeded under ambient temperature with a broad range of N-heteroaromatic compounds among which imidazo[1,2-a]pyridine derivatives were for the first time selectively reduced to 5,6,7,8-tetrahydroimidazo[1,2-a]pyridines, which are the core structural motifs of an inhibitor of human O-GlcNAcase.	Nitrogen	72-73	O-GlcNAcase	Homo sapiens	298-309
31271795-5	2019	CNC at a concentration of 0.3% (w/w) delayed diffusion of free amino nitrogen during intestinal digestion of milk protein.	Nitrogen	69-77	protein kinase cAMP-dependent type I regulatory subunit alpha	Homo sapiens	0-3
27617369-2	2016	Our study indicated that low nitrogen increases the NADPH/NADP(+) and ATP/AMP ratios which affect adenosine monophosphate-activated protein kinase (AMPK) activity and phosphorylation and abundance of nuclear CRY1 protein.	Nitrogen	29-37	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	98-146
27617369-2	2016	Our study indicated that low nitrogen increases the NADPH/NADP(+) and ATP/AMP ratios which affect adenosine monophosphate-activated protein kinase (AMPK) activity and phosphorylation and abundance of nuclear CRY1 protein.	Nitrogen	29-37	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	148-152
31302890-2	2019	The characteristics of total nitrogen (TN) production were studied by simulating the "dual structure" microenvironment of sloping farmland in a karst region using an artificial rainfall simulation method.	Nitrogen	29-37	C-type lectin domain family 3 member B	Homo sapiens	39-41
27177902-4	2016	TUSC3 was originally identified as part of an enzyme complex involved in N-glycosylation of proteins, but was recently implicated as a potential tumor suppressor gene in a variety of cancer types.	Nitrogen	73-74	tumor suppressor candidate 3	Homo sapiens	0-5
31539141-10	2019	Compared with controls, DM rats presented higher levels of kidney weight, 24 h-urine protein, blood urea nitrogen and serum creatinine, which were markedly reduced after TUG1 overexpression in vivo.	Nitrogen	105-113	taurine up-regulated 1	Rattus norvegicus	170-174
27459343-1	2016	Nitrogen incorporation to produce negative fixed charge in Al2O3 gate insulator layers is investigated as a path to achieve enhancement mode GaN device operation.	Nitrogen	0-8	gigaxonin	Homo sapiens	141-144
29964714-3	2016	The nitrogen amount of 300 kg hm-2 was applied in all treatments.	Nitrogen	4-12	Putative anthocyanidin reductase	Zea mays	30-34
31344260-6	2019	The TFE3 pathway regulates the general function of the Golgi, such as structural maintenance, N-glycosylation and vesicular transport, whereas the proteoglycan pathway increases the expression of glycosylation enzymes for proteoglycans.	Nitrogen	94-95	transcription factor binding to IGHM enhancer 3	Homo sapiens	4-8
27428707-8	2016	Because of the large energy difference between the single and triple nitrogen bonds, dissociation of the CaNx crystals with polynitrogens is expected to be highly exothermic, making them as potential high-energy-density materials.	Nitrogen	69-77	calnexin	Homo sapiens	105-109
31529876-5	2019	Mowing significantly reduced activities of the enzymes involved in nitrogen acquisition (N-acetyl-beta-D-glucosaminidase) and phosphorus acquisition (acidic phosphomonoesterases), which supports the resource allocation theory.	Nitrogen	67-75	O-GlcNAcase	Homo sapiens	89-120
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	solute carrier family 2 member 4	Homo sapiens	143-164
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	solute carrier family 2 member 4	Homo sapiens	166-171
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	solute carrier family 2 member 4	Homo sapiens	276-281
31266804-0	2019	Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.	Nitrogen	29-30	transient receptor potential cation channel subfamily C member 6	Homo sapiens	138-143
27428308-5	2016	Yap1 directly enhances glutamine synthetase (glul) expression and activity, elevating steady-state levels of glutamine and enhancing the relative isotopic enrichment of nitrogen during de novo purine and pyrimidine biosynthesis.	Nitrogen	169-177	Yes1 associated transcriptional regulator	Danio rerio	0-4
27428308-8	2016	Together, our findings demonstrate that Yap1 integrates the anabolic demands of tissue growth during development and tumorigenesis by reprogramming nitrogen metabolism to stimulate nucleotide biosynthesis.	Nitrogen	148-156	Yes1 associated transcriptional regulator	Danio rerio	40-44
27002602-8	2016	Docking indicated that the N-containing rings of OME possibly could interact with the iron atom of the heme for S-OME in CYP17A1 and S- and R-OME in CYP21A2.	Nitrogen	27-28	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	121-128
31266804-9	2019	However, mutating the two TRPC6 N-glycosylation sites abrogated the cytotoxicity of mutant TRPC6 and reduced its surface expression.	Nitrogen	32-33	transient receptor potential cation channel subfamily C member 6	Homo sapiens	26-31
27427963-1	2016	The cellular network composed of the evolutionarily conserved metabolic pathways of protein N-glycosylation, Wnt/beta-catenin signaling pathway, and E-cadherin-mediated cell-cell adhesion plays pivotal roles in determining the balance between cell proliferation and intercellular adhesion during development and in maintaining homeostasis in differentiated tissues.	Nitrogen	92-93	cadherin 1	Canis lupus familiaris	149-159
31266804-9	2019	However, mutating the two TRPC6 N-glycosylation sites abrogated the cytotoxicity of mutant TRPC6 and reduced its surface expression.	Nitrogen	32-33	transient receptor potential cation channel subfamily C member 6	Homo sapiens	91-96
31266804-10	2019	These results expand the targets of TMEM208-mediated ER translocation to include multipass transmembrane proteins and suggest that TRPC6 N-glycosylation plays multiple roles in modulating channel trafficking and activity.	Nitrogen	137-138	transient receptor potential cation channel subfamily C member 6	Homo sapiens	131-136
31063984-3	2019	The results show that both the unstrained monolayer 1H-NbN2 and 1H-TcN2 are 2D intrinsically ferromagnetic (FM) metal, in which the magnetic moment of the 1H-NbN2 and 1H-TcN2 comes mainly from the d orbitals of Nb atom and the p orbitals of N atom, respectively.	Nitrogen	55-56	transcobalamin 2	Homo sapiens	170-174
27185541-4	2016	The observed phase-I metabolites were formed through N-deethylation, N,N-deethylation, N-hydroxylation, and de-esterification, with CYP2B6 and CYP2C19 being the main enzymes catalyzing their formation.	Nitrogen	53-54	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	132-138
27023380-2	2016	At a COD/N ratio of 2.8 (COD, 390mg L(-1)) ammonium removal efficiency was 66%, while nitrite removal remained high (99%).	Nitrogen	9-10	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	25-28
27770224-2	2017	In this study, crucial genes like ARO8 and ARO10 of Ehrlich pathway for 2-PE synthesis and key transcription factor ARO80 in Saccharomyces cerevisiae were re-regulated using constitutive promoter; in the meantime, the effect of nitrogen source in synthetic complete (SC) medium with L-phenylalanine (L-Phe) on Aro8/Aro9 and Aro10 was investigated.	Nitrogen	228-236	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	43-48
27770224-2	2017	In this study, crucial genes like ARO8 and ARO10 of Ehrlich pathway for 2-PE synthesis and key transcription factor ARO80 in Saccharomyces cerevisiae were re-regulated using constitutive promoter; in the meantime, the effect of nitrogen source in synthetic complete (SC) medium with L-phenylalanine (L-Phe) on Aro8/Aro9 and Aro10 was investigated.	Nitrogen	228-236	Aro80p	Saccharomyces cerevisiae S288C	116-121
27770224-2	2017	In this study, crucial genes like ARO8 and ARO10 of Ehrlich pathway for 2-PE synthesis and key transcription factor ARO80 in Saccharomyces cerevisiae were re-regulated using constitutive promoter; in the meantime, the effect of nitrogen source in synthetic complete (SC) medium with L-phenylalanine (L-Phe) on Aro8/Aro9 and Aro10 was investigated.	Nitrogen	228-236	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	324-329
27023380-3	2016	However, at a COD/N ratio of 5.0 (COD, 300mg L(-1)), ammonium and nitrite removal efficiencies were high (84% and 99%, respectively).	Nitrogen	18-19	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	34-37
31063984-4	2019	Remarkably, two neighboring N atoms in the unstrained 1H-NbN2 form N-N bond, while those in the 1H-TcN2 do not.	Nitrogen	28-29	transcobalamin 2	Homo sapiens	99-103
31063984-5	2019	When lattice constant a increases to 3.17 A, monolayer 1H-TcN2 undergoes N-N nonbonding-bonding transition at which the distance between the N atoms d N-N suddenly drops by almost 25%.	Nitrogen	73-76	transcobalamin 2	Homo sapiens	58-62
31275011-5	2017	We previously showed that the plant specific ubiquitin ligase ATL31 regulates the carbon/nitrogen-nutrient response and pathogen resistance in Arabidopsis, and we identified and characterized the basic biochemical function of an ATL31 homologue in tomato plants (Solanum lycopersicum L.).	Nitrogen	89-97	carbon/nitrogen insensitive 1	Arabidopsis thaliana	62-67
31063984-6	2019	In particular, due to the bonding between two neighboring N atoms, the magnetic moment of N atoms in 1H-TcN2 are quenched and the ground state transfers to non-magnetic.	Nitrogen	58-59	transcobalamin 2	Homo sapiens	104-108
31275011-5	2017	We previously showed that the plant specific ubiquitin ligase ATL31 regulates the carbon/nitrogen-nutrient response and pathogen resistance in Arabidopsis, and we identified and characterized the basic biochemical function of an ATL31 homologue in tomato plants (Solanum lycopersicum L.).	Nitrogen	89-97	carbon/nitrogen insensitive 1	Arabidopsis thaliana	229-234
27364328-6	2016	N-CISSOR mimicked the subcellular localization and biochemical properties of NRG1 including cleavage dynamics and ErbB phosphorylation in cultured cells.	Nitrogen	0-1	neuregulin 1	Homo sapiens	77-81
31063984-6	2019	In particular, due to the bonding between two neighboring N atoms, the magnetic moment of N atoms in 1H-TcN2 are quenched and the ground state transfers to non-magnetic.	Nitrogen	90-91	transcobalamin 2	Homo sapiens	104-108
31283227-4	2019	Herein we describe the discovery of a potent non-nitrogen containing morpholine isostere with the ability to mimic this conformation and its application in a potent selective dual inhibitor of mTORC1 and mTORC2 (29b).	Nitrogen	49-57	CREB regulated transcription coactivator 1	Mus musculus	193-199
27191747-6	2016	CXCL16 knockout mice had lower blood urea nitrogen and less tubular damage following cisplatin-induced AKI as compared with wild-type mice.	Nitrogen	42-50	chemokine (C-X-C motif) ligand 16	Mus musculus	0-6
27694057-1	2016	The purpose of this study was to evaluate the effect of cyclization on the biological profile of a [99mTc(N)(PNP3)]-labeled alpha-melanocyte stimulating hormone peptide analog.	Nitrogen	105-108	pro-opiomelanocortin-alpha	Mus musculus	124-160
31283227-4	2019	Herein we describe the discovery of a potent non-nitrogen containing morpholine isostere with the ability to mimic this conformation and its application in a potent selective dual inhibitor of mTORC1 and mTORC2 (29b).	Nitrogen	49-57	CREB regulated transcription coactivator 2	Mus musculus	204-210
27520391-2	2016	Arabidopsis thaliana and other Brassicaceae contain an additional cytosolic fumarase (FUM2) that functions in carbon assimilation and nitrogen use.	Nitrogen	134-142	FUMARASE 2	Arabidopsis thaliana	86-90
30891880-8	2019	Some (CAG)n -containing genes including TBP, ATN1 and HTT modified AAO with variance ranging from 0.8% to 3.8% and tended to decrease or delay AAO.	Nitrogen	10-11	atrophin 1	Homo sapiens	45-49
27072136-4	2016	Of particular significance is the formation of a diazonium ion on the aromatic ring of the MOF, and the potential reduction of NO2 to molecular nitrogen.	Nitrogen	144-152	lysine acetyltransferase 8	Homo sapiens	91-94
27779385-2	2016	The formation and polymerization of methacrylic and styrenic HIPEs were possible through stabilization with nitrogen doped carbon nanotube (CNX) and surfactant mixtures using a urea-choline chloride DES as a delivering phase.	Nitrogen	108-116	calnexin	Homo sapiens	140-143
27097744-11	2016	Nitrogen addition increased N leaching to 73 kg N ha-1  yr-1 .	Nitrogen	0-8	solute carrier family 9 member B1	Homo sapiens	48-60
27097744-11	2016	Nitrogen addition increased N leaching to 73 kg N ha-1  yr-1 .	Nitrogen	0-1	solute carrier family 9 member B1	Homo sapiens	48-60
27032077-11	2016	UGT1A9, an abundant UGT isoform expressed in human liver and kidney, preferentially forms the O-linked Gluc conjugates of HONH-AalphaC and HONH-PhIP as opposed to their detoxicated N(2)-Gluc isomers.	Nitrogen	181-185	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	0-6
27003252-4	2016	In human sperm, TRPV4 is present as N-glycosylated protein and its activation induces Ca(2+)-influx.	Nitrogen	36-37	transient receptor potential cation channel subfamily V member 4	Homo sapiens	16-21
30891880-8	2019	Some (CAG)n -containing genes including TBP, ATN1 and HTT modified AAO with variance ranging from 0.8% to 3.8% and tended to decrease or delay AAO.	Nitrogen	10-11	huntingtin	Homo sapiens	54-57
31213504-5	2019	Two of TorC1"s many downstream targets are Gln3 and Gat1-GATA-family transcription activators-whose localization and function are Nitrogen Catabolite Repression- (NCR-) sensitive.	Nitrogen	130-138	Gat1p	Saccharomyces cerevisiae S288C	52-56
26976442-3	2016	Intracellular localization of the nitrogen-responsive transcription activator, Gln3, responds to four distinct nitrogen environments: nitrogen limitation or short-term starvation, i.e., nitrogen catabolite repression (NCR), long-term starvation, glutamine starvation, and rapamycin inhibition of mTorC1.	Nitrogen	34-42	CREB regulated transcription coactivator 1	Mus musculus	296-302
26589092-5	2016	A dietary N reduction alone resulted in a significant rise in plasma concentrations of bone resorption marker C-terminal telopeptide of type I collagen (CTX) and bone formation marker osteocalcin (OC), while reduced intake of Ca as well as the combination of both dietary interventions increased bone markers only slightly.	Nitrogen	10-11	osteocalcin	Capra hircus	184-195
26589092-5	2016	A dietary N reduction alone resulted in a significant rise in plasma concentrations of bone resorption marker C-terminal telopeptide of type I collagen (CTX) and bone formation marker osteocalcin (OC), while reduced intake of Ca as well as the combination of both dietary interventions increased bone markers only slightly.	Nitrogen	10-11	osteocalcin	Capra hircus	197-199
31213504-6	2019	In nitrogen replete environments, TorC1 is activated, thereby inhibiting the PTap42-Sit4 and PTap42-PP2A (Pph21/Pph22-Tpd3, Pph21,22-Rts1/Cdc55) phosphatase complexes.	Nitrogen	3-11	phosphoprotein phosphatase 2A catalytic subunit PPH21	Saccharomyces cerevisiae S288C	106-111
27636011-0	2016	A reliable compound-specific nitrogen isotope analysis of amino acids by GC-C-IRMS following derivatisation into N-pivaloyl-iso-propyl (NPIP)esters for high-resolution food webs estimation.	Nitrogen	29-37	guanylate cyclase 2C	Homo sapiens	73-77
27136596-2	2016	The formation of N-glycan branches catalyzed by specific N-acetylglucosaminyltransferases [GnT-III, GnT-IVs, GnT-V, GnT-IX (Vb)] and a fucosyltransferase, Fut8, provides functionally diverse N-glycosylated proteins.	Nitrogen	17-18	fucosyltransferase 8	Homo sapiens	155-159
31213504-6	2019	In nitrogen replete environments, TorC1 is activated, thereby inhibiting the PTap42-Sit4 and PTap42-PP2A (Pph21/Pph22-Tpd3, Pph21,22-Rts1/Cdc55) phosphatase complexes.	Nitrogen	3-11	phosphoprotein phosphatase 2A catalytic subunit PPH21	Saccharomyces cerevisiae S288C	124-129
30994636-1	2019	Hydrated singly charged magnesium ions [Mg(H2O)n]+ are thought to consist of an Mg2+ ion and a hydrated electron for n &gt; 15.	Nitrogen	11-12	mucin 7, secreted	Homo sapiens	80-83
26906474-4	2016	A hydroxyethylaminopropyl side chain on the lactam nitrogen of two halogenated indenoisoquinoline Top1 inhibitors was found to also impart inhibitory activity against tyrosyl DNA phosphodiesterases 1 and 2 (TDP1 and TDP2), which are enzymes that participate in the repair of DNA damage induced by Top1 poisons.	Nitrogen	51-59	tyrosyl-DNA phosphodiesterase 1	Homo sapiens	167-205
26906474-4	2016	A hydroxyethylaminopropyl side chain on the lactam nitrogen of two halogenated indenoisoquinoline Top1 inhibitors was found to also impart inhibitory activity against tyrosyl DNA phosphodiesterases 1 and 2 (TDP1 and TDP2), which are enzymes that participate in the repair of DNA damage induced by Top1 poisons.	Nitrogen	51-59	tyrosyl-DNA phosphodiesterase 1	Homo sapiens	207-211
27341695-6	2016	In addition, cre1 nodules exhibit an increased growth, whereas other chk mutants have no detectable phenotype, and the maintained nitrogen fixation capacity in cre1 requires other CHK genes.	Nitrogen	130-138	CHASE domain containing histidine kinase protein	Arabidopsis thaliana	13-17
27341695-6	2016	In addition, cre1 nodules exhibit an increased growth, whereas other chk mutants have no detectable phenotype, and the maintained nitrogen fixation capacity in cre1 requires other CHK genes.	Nitrogen	130-138	CHASE domain containing histidine kinase protein	Arabidopsis thaliana	160-164
31271171-5	2019	Upon excitation, bis-HPTA-II transfers a proton to a DMF molecule to form an anion and bis-HPTA-III transfers a proton to a ring nitrogen to form a keto form.	Nitrogen	129-137	hepatocyte growth factor	Homo sapiens	91-95
31188590-1	2019	Herein, we report a novel carbothermal welding strategy to prepare atomically dispersed Pd sites anchored on a three-dimensional (3D) ZrO2 nanonet (Pd1@ZrO2) via two-step pyrolysis, which were evolved from isolated Pd sites anchored on linker-derived nitrogen-doped carbon (Pd1@NC/ZrO2).	Nitrogen	251-259	programmed cell death 1	Homo sapiens	148-151
27422454-14	2016	In vitro experiments revealed that the total amount of released HMGB1 into the culture medium of empty capsule (200 capsules/dish) and microencapsulated NPI (200 IEQ/dish) after hypoxic culture (1% O2 , 5% CO2 , and 94% N2 ) was 0 and 8.6 +- 2.2 ng, respectively (P &lt; 0.001).	Nitrogen	220-222	high mobility group box 1	Mus musculus	64-69
27480168-0	2016	N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function.	Nitrogen	0-1	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	46-84
27501685-5	2016	RESULTS: The DNA concentration extracted by tooth crumb method, ball-milling method and liquid nitrogen milling method was 0.055 6-1.989 1 ng/muL, 0.036 6-1.175 6 ng/muL and 0.037 8-1.249 0 ng/muL, respectively.	Nitrogen	95-103	tripartite motif containing 37	Homo sapiens	142-145
26628609-1	2016	Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis.	Nitrogen	10-18	glutamate synthase 1	Arabidopsis thaliana	130-148
26628609-1	2016	Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis.	Nitrogen	10-18	aspartate aminotransferase	Arabidopsis thaliana	158-184
26628609-1	2016	Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis.	Nitrogen	10-18	aspartate aminotransferase	Arabidopsis thaliana	186-191
27480168-0	2016	N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function.	Nitrogen	0-1	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	86-90
27480168-5	2016	Substitution of N48 prevents hENT1 glycosylation, confirming a single N-linked glycosylation site.	Nitrogen	16-17	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	29-34
26309237-1	2016	Bacteria and archaea have evolved with the ability to fix atmospheric dinitrogen in the form of ammonia, catalyzed by the nitrogenase enzyme complex which comprises three structural genes nifK, nifD and nifH.	Nitrogen	70-80	nucleolar protein interacting with the FHA domain of MKI67	Homo sapiens	188-192
27216994-13	2016	Furthermore, we found that 11 out of 12 predicted N-glycosylation sites in GluN1 and 7 out of 7 N-glycosylation sites in GluN2B are occupied by N-glycans.	Nitrogen	50-51	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	121-127
27216994-13	2016	Furthermore, we found that 11 out of 12 predicted N-glycosylation sites in GluN1 and 7 out of 7 N-glycosylation sites in GluN2B are occupied by N-glycans.	Nitrogen	78-79	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	121-127
25587188-11	2016	As N-linked glycosylation requires glycosylation consensus sites in the protein sequence and as these are lacking in the "germline-counterparts" of identified variable domains, our data indicate that the N-glycosylation sites in ACPA variable domains have been introduced by somatic hypermutation.	Nitrogen	3-4	proteinase 3	Homo sapiens	229-233
25587188-11	2016	As N-linked glycosylation requires glycosylation consensus sites in the protein sequence and as these are lacking in the "germline-counterparts" of identified variable domains, our data indicate that the N-glycosylation sites in ACPA variable domains have been introduced by somatic hypermutation.	Nitrogen	204-205	proteinase 3	Homo sapiens	229-233
27030648-15	2016	Compared with those of patients in group CT, creatinine at PIH 48 and urea nitrogen at PIH 24, 48, 72 were obviously lower in group BP (with t values from -4.23 to -2.44, P&lt;0.05 or P&lt;0.01).	Nitrogen	75-83	pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included)	Homo sapiens	87-90
31241343-1	2019	We have shown that both the morphology and elongation mechanism of GaN nanowires homoepitaxially grown by plasma-assisted molecular beam epitaxy (PA-MBE) on a [0001]-oriented GaN nanowire template are strongly affected by the nominal gallium/nitrogen flux ratio as well as by additional Ga flux diffusing from the side walls.	Nitrogen	242-250	gigaxonin	Homo sapiens	67-70
26794841-3	2016	SbnA is a pyridoxal 5"-phosphate (PLP)-dependent enzyme with homology to O-acetyl-l-serine sulfhydrylases; however, SbnA utilizes OPS instead of O-acetyl-l-serine (OAS), and l-glutamate serves as a nitrogen donor instead of a sulfide.	Nitrogen	198-206	pyridoxal phosphatase	Homo sapiens	34-37
27269411-4	2016	In this study, nitrogen-doped carbon nanotube membranes and Pt carbon cloths were utilized as filtration material and cathode to fabricate a modularized filtration air cathode MDC (F-MDC).	Nitrogen	15-23	C-C motif chemokine ligand 22	Homo sapiens	176-179
27269411-4	2016	In this study, nitrogen-doped carbon nanotube membranes and Pt carbon cloths were utilized as filtration material and cathode to fabricate a modularized filtration air cathode MDC (F-MDC).	Nitrogen	15-23	C-C motif chemokine ligand 22	Homo sapiens	181-186
31660484-1	2019	Background: B-type natriuretic peptide (BNP) and the N-terminal proBNP (NT-proBNP) exhibit different evolution in chronic heart failure patients with reduced ejection fraction treated with Sacubitril/Valsartan; BNP increasing or remaining stable, while NT-proBNP decreases.	Nitrogen	41-42	natriuretic peptide B	Homo sapiens	12-38
27207520-5	2016	Glucose stimulation expectedly induced Syt-7 association in a Ca(2+)-dependent manner with syntaxin-3 and syntaxin-1A soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes known to mediate exocytosis of newcomer and predocked SGs, respectively.	Nitrogen	126-127	synaptotagmin 7	Homo sapiens	39-44
26595189-1	2016	Thyroglobulin (Tg) is a vertebrate secretory protein synthesized in the thyrocyte endoplasmic reticulum (ER), where it acquires N-linked glycosylation and conformational maturation (including formation of many disulfide bonds), leading to homodimerization.	Nitrogen	128-129	thyroglobulin	Homo sapiens	0-13
31060002-7	2019	RESULTS: In the in vivo animal tests, RLX administration prevented increased plasma creatinine and nitrogen levels caused by aristolochic acid as well as alleviated the severity of renal ultrastructural lesions induced by aristolochic acid.	Nitrogen	99-107	relaxin 1	Mus musculus	38-41
26637370-4	2016	Downregulation of these critical survival pathways is shown to be due to 2-DG"s interference with N-linked glycosylation, leading to alterations in VEGFR2 (and downstream signaling) as well as induction of endoplasmic reticulum (ER) stress, GSK3beta activation, and apoptosis.	Nitrogen	98-99	kinase insert domain protein receptor	Mus musculus	148-154
27038031-3	2016	IgM can exist as a pentamer with a connecting singly N-glycosylated J-chain (with a total of 51 glycosylation sites) or as a hexamer (60 glycosylation sites).	Nitrogen	53-54	joining chain of multimeric IgA and IgM	Homo sapiens	68-75
27314333-0	2016	N-Glycosylation of Human R-Spondin 1 Is Required for Efficient Secretion and Stability but Not for Its Heparin Binding Ability.	Nitrogen	0-1	R-spondin 1	Homo sapiens	25-36
27314333-4	2016	Using chemical inhibitors, deglycosylase and site-directed mutagenesis, we found that human Rspo1 and Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosylated at N160, a position near the N-terminus of TSR1 domain.	Nitrogen	117-118	R-spondin 1	Homo sapiens	92-97
27314333-4	2016	Using chemical inhibitors, deglycosylase and site-directed mutagenesis, we found that human Rspo1 and Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosylated at N160, a position near the N-terminus of TSR1 domain.	Nitrogen	135-136	R-spondin 1	Homo sapiens	92-97
27314333-6	2016	Introduction of the N-glycosylation site to Rspo2 mutant at the position homologous to N137 in Rspo1 restored full glycosylation and rescued the accumulation defect of nonglycosylated Rspo2 mutant in media.	Nitrogen	20-21	R-spondin 1	Homo sapiens	95-100
26767057-9	2016	Furthermore, KAT2B was associated with AAA diameter (r = 0.382, P &lt; 0.05), and KAT3B, KAT6A, and KAT6B correlated negatively with blood urea nitrogen (r = -0.403, -0.408, -0.478, P &lt; 0.05).	Nitrogen	144-152	E1A binding protein p300	Homo sapiens	82-87
27314333-7	2016	Similar effect can be observed in the N137 Rspo1 or Rspo3 mutant engineered with Rspo2 N-glycosylation site.	Nitrogen	38-39	R-spondin 1	Homo sapiens	43-48
31075232-9	2019	KEY FINDINGS: ETaR siRNA treatment reduced the levels of serum creatinine and urea nitrogen, decreased the number of apoptotic cells, and ameliorated histological damage after IRI.	Nitrogen	83-91	endothelin receptor type A	Homo sapiens	14-18
27227887-5	2016	These phenotypes were rescued by TORC1 inhibition using pharmacological or genetic means, and the loss of Lam2, Gtr1, Gtr2, Npr2 or Npr3 disinhibited TORC1 activity under nitrogen depletion, as measured by Rps6 phosphorylation.	Nitrogen	171-179	CREB regulated transcription coactivator 1	Mus musculus	150-155
26700048-0	2016	Characterization of Protein N-Glycosylation by Analysis of ZIC-HILIC-Enriched Intact Proteolytic Glycopeptides.	Nitrogen	28-29	Zic family member 1	Homo sapiens	59-62
26700048-1	2016	Zwitterionic hydrophilic interaction chromatography (ZIC-HILIC) solid-phase extraction (SPE) combined with direct-infusion nanoESI mass spectrometry (MS) and tandem MS/MS is a well-suited method for the analysis of protein N-glycosylation.	Nitrogen	223-224	Zic family member 1	Homo sapiens	53-56
31266720-1	2019	Deficiency of Dolichol-P-mannose synthase subunit 3 (DPM3) affects the N-glycosylation and O-mannosylation pathways that are respectively involved in congenital disorders of glycosylation (CDG) and alpha-dystroglycanopathies.	Nitrogen	71-72	dolichyl-phosphate mannosyltransferase subunit 3, regulatory	Homo sapiens	53-57
27018849-5	2016	Intriguingly, nitrate to ammonium conversion is impaired in pdx3 mutants, such that the mutants become ammonium-dependent, suggesting an interaction between vitamin B6 and nitrogen metabolism.	Nitrogen	172-180	pyridoxin (pyrodoxamine) 5'-phosphate oxidase	Arabidopsis thaliana	60-64
27018849-7	2016	Here, we further show that pdx3 mutants display a temperature-sensitive phenotype that is typical of autoimmune mutants and is possibly connected to the impaired nitrogen metabolism.	Nitrogen	162-170	pyridoxin (pyrodoxamine) 5'-phosphate oxidase	Arabidopsis thaliana	27-31
26936875-0	2016	N-sulfation of heparan sulfate is critical for syndecan-4-mediated podocyte cell-matrix interactions.	Nitrogen	0-1	syndecan 4	Mus musculus	47-57
27123103-0	2016	N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/beta-catenin signaling-enhancing activity.	Nitrogen	0-1	R-spondin 1	Homo sapiens	19-29
27123103-2	2016	It has been predicted that R-spondin1 (RSPO1) is N-glycosylated, although this remains unknown.	Nitrogen	49-50	R-spondin 1	Homo sapiens	27-37
27123103-2	2016	It has been predicted that R-spondin1 (RSPO1) is N-glycosylated, although this remains unknown.	Nitrogen	49-50	R-spondin 1	Homo sapiens	39-44
27123103-3	2016	The present study identified that RSPO1 was N-glycosylated at Asn137, and that N-glycosylation of RSPO1 negatively influenced its secretion and enhancing effect on Wnt/beta-catenin signaling.	Nitrogen	44-45	R-spondin 1	Homo sapiens	34-39
26681516-2	2015	Studies in yeast and human cells have shown that nitrogen/amino acid starvation signals act through Npr2/Npr3 and the small GTPases Gtr1/Gtr2 (Rags in humans) to inhibit TORC1.	Nitrogen	49-57	natriuretic peptide receptor 2	Homo sapiens	100-104
26681516-2	2015	Studies in yeast and human cells have shown that nitrogen/amino acid starvation signals act through Npr2/Npr3 and the small GTPases Gtr1/Gtr2 (Rags in humans) to inhibit TORC1.	Nitrogen	49-57	CREB regulated transcription coactivator 1	Homo sapiens	170-175
27123103-3	2016	The present study identified that RSPO1 was N-glycosylated at Asn137, and that N-glycosylation of RSPO1 negatively influenced its secretion and enhancing effect on Wnt/beta-catenin signaling.	Nitrogen	79-80	R-spondin 1	Homo sapiens	98-103
31266720-7	2019	The present study highlights several aspects related to DPM3 gene mutations such as mild to moderately severe limb-girdle muscular dystrophy, dilated cardiomyopathy, and abnormal N-glycosylation profile suggestive of CDG type 1.	Nitrogen	179-180	dolichyl-phosphate mannosyltransferase subunit 3, regulatory	Homo sapiens	56-60
27123103-5	2016	Furthermore, treatment of wild-type (wt) RSPO1-overexpressing HT1080 cells with tunicamycin (TM), which inhibits N-glycosylation, resulted in a significant reduction in the molecular weight of RSPO1.	Nitrogen	113-114	R-spondin 1	Homo sapiens	41-46
27123103-7	2016	These results demonstrated for the first time that RSPO1 is N-glycosylated at Asn137.	Nitrogen	60-61	R-spondin 1	Homo sapiens	51-56
30734493-5	2019	Cr(VI) photoreduction rate of N-CQDs/SnS2 is highly enhanced by engineering the loading contents of N-CQDs, in which the optimal N-CQDs/SnS2 with 40 mol% N-CQDs exhibits a remarkable Cr(VI) photoreduction rate of 0.148 min-1 , about 5-time and 148-time higher than that of SnS2 and N-CQDs, respectively.	Nitrogen	30-31	sodium voltage-gated channel alpha subunit 11	Homo sapiens	37-41
27123103-9	2016	The role of N-glycosylation in RSPO1 was evaluated by conducting comparative experiments with wt and N137Q RSPO1, which revealed that the N137Q mutant increased the secretion and Wnt/beta-catenin signaling-enhancing effect of RSPO1, compared with wt RSPO1.	Nitrogen	12-13	R-spondin 1	Homo sapiens	31-36
27123103-10	2016	These results suggest that N-glycosylation of RSPO1 has a negative influence on its secretion and Wnt/beta-catenin signaling-enhancing effect.	Nitrogen	27-28	R-spondin 1	Homo sapiens	46-51
26468284-0	2015	Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25.	Nitrogen	69-70	interleukin 2 receptor subunit alpha	Homo sapiens	95-99
26468284-3	2015	We demonstrate that glucosamine impedes Th1, Th2, and iTreg but promotes Th17 differentiation through down-regulating N-linked glycosylation of CD25 and subsequently inhibiting its downstream Stat5 signaling in a dose-dependent manner.	Nitrogen	118-119	interleukin 2 receptor subunit alpha	Homo sapiens	144-148
26468284-9	2015	Taken together, our results indicate that glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 downstream signaling.	Nitrogen	70-71	interleukin 2 receptor subunit alpha	Homo sapiens	89-93
30734493-5	2019	Cr(VI) photoreduction rate of N-CQDs/SnS2 is highly enhanced by engineering the loading contents of N-CQDs, in which the optimal N-CQDs/SnS2 with 40 mol% N-CQDs exhibits a remarkable Cr(VI) photoreduction rate of 0.148 min-1 , about 5-time and 148-time higher than that of SnS2 and N-CQDs, respectively.	Nitrogen	30-31	sodium voltage-gated channel alpha subunit 11	Homo sapiens	136-140
30734493-5	2019	Cr(VI) photoreduction rate of N-CQDs/SnS2 is highly enhanced by engineering the loading contents of N-CQDs, in which the optimal N-CQDs/SnS2 with 40 mol% N-CQDs exhibits a remarkable Cr(VI) photoreduction rate of 0.148 min-1 , about 5-time and 148-time higher than that of SnS2 and N-CQDs, respectively.	Nitrogen	30-31	sodium voltage-gated channel alpha subunit 11	Homo sapiens	136-140
27016446-9	2016	Overall, these results show that AAP8 plays an important role in source-to-sink partitioning of nitrogen and that its function affects source leaf physiology and seed yield.	Nitrogen	96-104	amino acid permease 8	Arabidopsis thaliana	33-37
31247951-6	2019	We report protein-specific N-glycosylation patterns, including a correlation of core fucosylated structures with immunoglobulin G (IgG) levels, and of trisialylated, trigalactosylated, and triantennary structures with heparin cofactor 2 (SERPIND2).	Nitrogen	27-28	serpin family D member 1	Homo sapiens	218-236
26993603-0	2016	GP73 N-glycosylation at Asn144 reduces hepatocellular carcinoma cell motility and invasiveness.	Nitrogen	5-6	golgi membrane protein 1	Homo sapiens	0-4
26496797-8	2015	The observed antihypertension activity of N-glycosylated MRJP1 in two RJ samples and a stronger activity found in Acc than in Aml reveal that specific RJ protein and modification are potentially useful for the treatment of hypertensive disease for humans.	Nitrogen	42-43	major royal jelly protein 1	Apis cerana	57-62
26538210-5	2015	The N-glycome of the fut-1;fut-6 mutant was the most complex of the three double-mutant strains due to the extension of the core alpha1,6-fucose as well as the presence of fucose on the bisecting galactose.	Nitrogen	4-5	Alpha-(1,3)-fucosyltransferase fut-1	Caenorhabditis elegans	21-32
26993603-3	2016	We identified three GP73 N-glycosylation sites: Asn109, Asn144 and Asn398.	Nitrogen	25-26	golgi membrane protein 1	Homo sapiens	20-24
30964658-1	2019	Nitrogen mustard, mechlorethamine (bis(2-chloroethyl)methylamine; HN2), and sulfur mustard are potent vesicants that modify and disrupt cellular macromolecules including DNA leading to cytotoxicity and tissue injury.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	66-69
27226773-6	2016	Further analysis by a lectin-based study revealed that aberrant O-glycosylated CDH, N-glycosylated MMP-13 and LOC were present in the 4T1 medium.	Nitrogen	84-85	matrix metallopeptidase 13	Mus musculus	99-105
26997130-2	2016	The [HAN](.-) radical can be transferred to the cobalt(II) amide [Co{N(SiMe3 )2 }2 ], forming [K(18-c-6)][(HAN){Co(N"")2 }3 ]; magnetic measurements on this compound reveal an S=4 spin system with strong cobalt-ligand antiferromagnetic exchange and J -290 cm(-1) (-2 J formalism).	Nitrogen	115-118	complement C6	Homo sapiens	100-103
26977717-1	2016	This article demonstrates a series of cyclometalated Ir(III) complexes of the type [Ir(III)(C^N)2(N^N)](PF6), where C^N is 2-phenylpyridine, and N^N corresponds to the 4,4"-pi-conjugated 2,2"-bipyridine ancillary ligands.	Nitrogen	94-95	sperm associated antigen 17	Homo sapiens	104-107
26342810-1	2015	Serum GP73 is a functional resident Golgi type II membrane protein with three potential N-glycosylation sites.	Nitrogen	88-89	golgi membrane protein 1	Homo sapiens	6-10
27112005-9	2015	N fertilizer use efficiency increased with increasing N level within N supply range of 0-435 kg   hm-2 and then dropped markedly when N rate above 435 kg   hm-2 It was found that the water productivity of irrigation (WP i increased with increasing N level, while, that decreased with increasing irrigation rate.	Nitrogen	0-1	Putative anthocyanidin reductase	Zea mays	98-102
27112005-9	2015	N fertilizer use efficiency increased with increasing N level within N supply range of 0-435 kg   hm-2 and then dropped markedly when N rate above 435 kg   hm-2 It was found that the water productivity of irrigation (WP i increased with increasing N level, while, that decreased with increasing irrigation rate.	Nitrogen	0-1	Putative anthocyanidin reductase	Zea mays	156-160
30872163-1	2019	ALG13 (asparagine-linked glycosylation 13 homolog) encodes a crucial protein involved in the process of N-linked glycosylation, and abnormal N-linked glycosylation is considered an important risk factor that leads to neurological deficits and disorders.	Nitrogen	104-105	asparagine-linked glycosylation 13	Mus musculus	0-5
26555173-4	2015	Xenograft studies reveal that blocking SCAP N-glycosylation ameliorates EGFRvIII-driven glioblastoma growth.	Nitrogen	44-45	SREBF chaperone	Homo sapiens	39-43
26555173-6	2015	Targeting SCAP N-glycosylation may provide a promising means of treating malignancies and metabolic diseases.	Nitrogen	15-16	SREBF chaperone	Homo sapiens	10-14
27250875-3	2016	By deploying a genetic screen for suppressors of cell death triggered by virus-induced gene silencing of BAK1/SERK4 on Arabidopsis knockout collections, we identified STT3a, a protein involved in N-glycosylation modification, as an important regulator of bak1/serk4 cell death.	Nitrogen	196-197	BRI1-associated receptor kinase	Arabidopsis thaliana	255-259
27250875-7	2016	Therefore, N-glycosylation and specific ERQC components are essential to activate bak1/serk4 cell death, and CRK4 is likely to be among client proteins of protein glycosylation involved in BAK1/SERK4-regulated cell death.	Nitrogen	11-12	BRI1-associated receptor kinase	Arabidopsis thaliana	82-86
27250875-7	2016	Therefore, N-glycosylation and specific ERQC components are essential to activate bak1/serk4 cell death, and CRK4 is likely to be among client proteins of protein glycosylation involved in BAK1/SERK4-regulated cell death.	Nitrogen	11-12	BRI1-associated receptor kinase	Arabidopsis thaliana	189-193
30872163-1	2019	ALG13 (asparagine-linked glycosylation 13 homolog) encodes a crucial protein involved in the process of N-linked glycosylation, and abnormal N-linked glycosylation is considered an important risk factor that leads to neurological deficits and disorders.	Nitrogen	104-105	asparagine-linked glycosylation 13	Mus musculus	7-49
26448038-6	2015	Notably, our results suggest that the modification of the N-capping region could alter the binding specificity of PACAP without altering its biological activity, thereby opening the way for the design of more selective compounds.	Nitrogen	0-1	adenylate cyclase activating polypeptide 1	Homo sapiens	114-119
26659906-1	2016	We describe the 3D supramolecular structure of Fmoc-RGDS fibrils, where Fmoc and RGDS refer to the hydrophobic N-(fluorenyl-9-methoxycarbonyl) group and the hydrophilic Arg-Gly-Asp-Ser peptide sequence, respectively.	Nitrogen	111-112	ral guanine nucleotide dissociation stimulator	Homo sapiens	52-56
31236271-8	2019	The low RFI cows had lower milk urea nitrogen than that in the high RFI cows (P = 0.05).	Nitrogen	37-45	RFI	Bos taurus	8-11
26659906-1	2016	We describe the 3D supramolecular structure of Fmoc-RGDS fibrils, where Fmoc and RGDS refer to the hydrophobic N-(fluorenyl-9-methoxycarbonyl) group and the hydrophilic Arg-Gly-Asp-Ser peptide sequence, respectively.	Nitrogen	111-112	ral guanine nucleotide dissociation stimulator	Homo sapiens	81-85
26651496-1	2016	Metal-organic frameworks (MOFs) can exhibit exceptionally high surface areas, which are experimentally estimated by applying the BET theory to measured nitrogen isotherms.	Nitrogen	152-160	delta/notch like EGF repeat containing	Homo sapiens	129-132
26104860-3	2015	Enantioselective CE with highly sulfated gamma-cyclodextrin as chiral selector was employed for analyzing in vitro (i) the kinetics of the N-demethylation of ketamine mediated by canine CYP3A12 and (ii) interactions occurring with racemic medetomidine and dexmedetomidine during coincubation with ketamine and canine liver microsomes (CLM), canine CYP3A12, human liver microsomes (HLM), and human CYP3A4.	Nitrogen	139-140	cytochrome P450 3A12	Canis lupus familiaris	186-193
26104860-3	2015	Enantioselective CE with highly sulfated gamma-cyclodextrin as chiral selector was employed for analyzing in vitro (i) the kinetics of the N-demethylation of ketamine mediated by canine CYP3A12 and (ii) interactions occurring with racemic medetomidine and dexmedetomidine during coincubation with ketamine and canine liver microsomes (CLM), canine CYP3A12, human liver microsomes (HLM), and human CYP3A4.	Nitrogen	139-140	cytochrome P450 3A12	Canis lupus familiaris	348-355
26651496-2	2016	The Brunauer, Emmett, and Teller (BET)-estimated nitrogen monolayer loading is thus converted to a "BET area," but the meaning of MOF BET areas remains under debate.	Nitrogen	49-57	delta/notch like EGF repeat containing	Homo sapiens	34-37
31236271-10	2019	Compared with high RFI animals, the low RFI cows had a lower retention of N (5.72 vs. 51.4 g/d, P &lt; 0.05) and a higher partition of feed N to milk N (29.7% vs. 26.5%, P &lt; 0.05).	Nitrogen	74-75	RFI	Bos taurus	40-43
26651496-2	2016	The Brunauer, Emmett, and Teller (BET)-estimated nitrogen monolayer loading is thus converted to a "BET area," but the meaning of MOF BET areas remains under debate.	Nitrogen	49-57	delta/notch like EGF repeat containing	Homo sapiens	100-103
26651496-2	2016	The Brunauer, Emmett, and Teller (BET)-estimated nitrogen monolayer loading is thus converted to a "BET area," but the meaning of MOF BET areas remains under debate.	Nitrogen	49-57	delta/notch like EGF repeat containing	Homo sapiens	100-103
30715692-4	2019	Mice fed with HFD exhibited higher levels of renal miR-155, which positively correlated with urine microalbumin and blood urea nitrogen.	Nitrogen	127-135	microRNA 155	Mus musculus	51-58
26567215-0	2016	The Ccl1-Kin28 kinase complex regulates autophagy under nitrogen starvation.	Nitrogen	56-64	Kin17 DNA and RNA binding protein	Homo sapiens	9-12
25966853-4	2015	The results clearly demonstrate that the structure of the N-linked side chain of SMTP congeners markedly affect their activities toward plasminogen modulation and inhibitions of the two activities of sEH (C-terminal epoxide hydrolase and N-terminal phosphatase).	Nitrogen	58-59	epoxide hydrolase 2	Homo sapiens	200-203
25966853-6	2015	Many congeners, which lacked plasminogen modulation activity, differently inhibited the two sEH activities depending on the structures of the N-linked side chain.	Nitrogen	142-143	epoxide hydrolase 2	Homo sapiens	92-95
26567221-0	2016	N-linked glycosylation plays a crucial role in the secretion of HMGB1.	Nitrogen	0-1	high mobility group box 1	Homo sapiens	64-69
31378723-1	2019	OBJECTIVE: The aim of this study was to investigate the effect of buspirone, as a partial agonist of 5-HT1A receptors, 8-hydroxy-2-[di-n-propylamino]-tetralin (8-OH-DPAT) as an agonist of 5-HT1A receptors and fluoxetine as a selective serotonin reuptake inhibitor on haloperidol-induced extrapyramidal symptoms (EPS) in male Wistar rats.	Nitrogen	41-42	5-hydroxytryptamine receptor 1A	Rattus norvegicus	101-107
26567221-3	2016	Here, we identified the role of N-glycosylation of HMGB1 in extracellular secretion.	Nitrogen	32-33	high mobility group box 1	Homo sapiens	51-56
26567221-4	2016	We found two consensus (N37 and N134) and one non-consensus (N135) residues that were N-glycosylated in HMGB1 by performing liquid chromatography tandem mass spectrometry (LC-MS/MS) and analyzing for N-glycan composition and structure.	Nitrogen	24-25	high mobility group box 1	Homo sapiens	104-109
26567221-5	2016	Inhibition of N-glycosylation with tunicamycin resulted in a molecular shift of HMGB1 as assessed by gel electrophoresis.	Nitrogen	14-15	high mobility group box 1	Homo sapiens	80-85
26567221-8	2016	Taken together, we propose that HMGB1 is N-glycosylated, and that this is important for its DNA interaction and is a prerequisite for its nucleocytoplasmic transport and extracellular secretion.	Nitrogen	41-42	high mobility group box 1	Homo sapiens	32-37
26344132-0	2016	N-Myristoylation of the Rpt2 subunit of the yeast 26S proteasome is implicated in the subcellular compartment-specific protein quality control system.	Nitrogen	0-1	proteasome regulatory particle base subunit RPT2	Saccharomyces cerevisiae S288C	24-28
26344132-7	2016	Taken together, our results indicate that N-myristoylation of Rpt2 is involved in controlled proteolysis via regulation of the nucleo-cytoplasmic localization of the yeast proteasome.	Nitrogen	42-43	proteasome regulatory particle base subunit RPT2	Saccharomyces cerevisiae S288C	62-66
26641062-13	2015	Plasma IGF-1 concentrations on d 0 and urea nitrogen on d 1 and 3, relative to vaccination, were greater for S7 vs. S3 steers ( &lt;= 0.008).	Nitrogen	44-52	leiomodin 1	Homo sapiens	56-65
26359303-7	2015	We show that alteration in N-linked glycosylation, caused by an alg9 mutation with a plasmid insertion (alg9(ins)) or tunicamycin treatment, can partially suppress the developmental phenotypes caused by tgrC1 deletion or replacement with an incompatible allele.	Nitrogen	27-28	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	64-68
26359303-7	2015	We show that alteration in N-linked glycosylation, caused by an alg9 mutation with a plasmid insertion (alg9(ins)) or tunicamycin treatment, can partially suppress the developmental phenotypes caused by tgrC1 deletion or replacement with an incompatible allele.	Nitrogen	27-28	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	104-108
26478188-7	2015	We also revealed that these effects of dimeric CMP-Ang1 were affected by specified N-glycosylation in its fibrinogen-like domain.	Nitrogen	83-84	angiopoietin 1	Homo sapiens	51-55
31378723-1	2019	OBJECTIVE: The aim of this study was to investigate the effect of buspirone, as a partial agonist of 5-HT1A receptors, 8-hydroxy-2-[di-n-propylamino]-tetralin (8-OH-DPAT) as an agonist of 5-HT1A receptors and fluoxetine as a selective serotonin reuptake inhibitor on haloperidol-induced extrapyramidal symptoms (EPS) in male Wistar rats.	Nitrogen	41-42	5-hydroxytryptamine receptor 1A	Rattus norvegicus	188-194
27546995-12	2016	Pearson correlation analysis indicated that serum adropin was negatively correlated with body mass index (BMI), blood urea nitrogen, creatinine, and ACR and positively correlated with glomerular filtration rate.	Nitrogen	123-131	energy homeostasis associated	Homo sapiens	50-57
31147541-0	2019	Natural variation of BSK3 tunes brassinosteroid signaling to regulate root foraging under low nitrogen.	Nitrogen	94-102	BR-signaling kinase 3	Arabidopsis thaliana	21-25
26582727-4	2016	Cloning the Rj4 gene is the first step in understanding the molecular basis of Rj4-mediated nodulation restriction and facilitates the development of molecular tools for genetic improvement of nitrogen fixation in soybeans.	Nitrogen	193-201	thaumatin-like protein 1	Glycine max	12-15
26318452-1	2015	Ceramide synthases (CerS1-CerS6), which catalyze the N-acylation of the (dihydro)sphingosine backbone to produce (dihydro)ceramide in both the de novo and the salvage or recycling pathway of ceramide generation, have been implicated in the control of programmed cell death.	Nitrogen	53-54	ceramide synthase 6	Homo sapiens	26-31
31147541-5	2019	We further show that low N specifically upregulates transcript levels of the BR co-receptor BAK1 to activate BR signaling and stimulate root elongation.	Nitrogen	25-26	BRI1-associated receptor kinase	Arabidopsis thaliana	92-96
26224316-8	2015	Finally, we show that N-glycosylation of JAM-A regulates leukocyte adhesion and LFA-1 binding.	Nitrogen	22-23	integrin subunit alpha L	Homo sapiens	80-85
30844566-1	2019	Fe and N functionalized hollow carbon spheres (Fe/N-HCS) with hierarchically porous structure are constructed.	Nitrogen	7-8	holocarboxylase synthetase	Homo sapiens	52-55
26221031-6	2015	This affected the outcome of processing of a substrate containing a nitrogen mustard-like ICL two nucleotides in the duplex region because FAN1, unlike EXO1 and FEN1, incised the substrate predominantly beyond the ICL and, therefore, failed to release the 5" flap.	Nitrogen	68-76	FANCD2 and FANCI associated nuclease 1	Homo sapiens	139-143
26161459-13	2016	CYP2C8 inhibitors reduced HLM N-demethylation by 47-75%, compared to 0-30% for CYP3A4 inhibitors.	Nitrogen	30-31	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	0-6
30844566-1	2019	Fe and N functionalized hollow carbon spheres (Fe/N-HCS) with hierarchically porous structure are constructed.	Nitrogen	50-51	holocarboxylase synthetase	Homo sapiens	52-55
26257095-7	2015	Nitrogen adsorption-desorption results showed that the carbon materials had large BET surface area and pore volume, e.g., 1426 m(2)/g and 1.67 cm(3)/g for the sample carbonized at 800 C. Moreover, the pore structure and surface chemistry compositions were tunable, as they were sensitive to the temperature.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	82-85
31139622-0	2019	Heterostructured SnO2-SnS2@C Embedded in Nitrogen-Doped Graphene as a Robust Anode Material for Lithium-Ion Batteries.	Nitrogen	41-49	sodium voltage-gated channel alpha subunit 11	Homo sapiens	22-26
26657071-8	2015	Overall the results indicate that preventing N-glycosylation of hCES1 does not significantly affect the structure or activity of the enzyme.	Nitrogen	45-46	carboxylesterase 1	Homo sapiens	64-69
31139622-3	2019	Here, SnO2-SnS2@C nanoparticles with heterostructure embedded in a carbon matrix of nitrogen-doped graphene (SnO2-SnS2@C/NG) is ingeniously designed in this work.	Nitrogen	84-92	sodium voltage-gated channel alpha subunit 11	Homo sapiens	11-15
31139622-3	2019	Here, SnO2-SnS2@C nanoparticles with heterostructure embedded in a carbon matrix of nitrogen-doped graphene (SnO2-SnS2@C/NG) is ingeniously designed in this work.	Nitrogen	84-92	sodium voltage-gated channel alpha subunit 11	Homo sapiens	114-118
31139622-6	2019	It should be noted that a carbon matrix with nitrogen-doped graphene can inhibit the volume expansion of SnO2-SnS2 nanoparticles and promote the transport of lithium ions during continuous cycling.	Nitrogen	45-53	sodium voltage-gated channel alpha subunit 11	Homo sapiens	110-114
26575002-3	2015	This novel property, made possible by the electron-deficient nitrogen ions, render transition-metal dinitrides monolayers with unique electronic properties which can be switched from the ferromagnetic metals in MoN2, ZrN2, and TcN2 to half-metallic ones in YN2.	Nitrogen	61-69	MON2 homolog, regulator of endosome-to-Golgi trafficking	Homo sapiens	211-215
31139622-7	2019	Benefiting from the synergistic effect between nanoparticles and carbon matrix with nitrogen-doped graphene, the heterostructured SnO2-SnS2@C/NG further fundamentally confer improved structural stability and reaction kinetics for lithium storage.	Nitrogen	84-92	sodium voltage-gated channel alpha subunit 11	Homo sapiens	135-139
26575002-3	2015	This novel property, made possible by the electron-deficient nitrogen ions, render transition-metal dinitrides monolayers with unique electronic properties which can be switched from the ferromagnetic metals in MoN2, ZrN2, and TcN2 to half-metallic ones in YN2.	Nitrogen	61-69	transcobalamin 2	Homo sapiens	227-231
25224404-8	2015	In contrast, the N-acetylated metabolite of 2-aminofluorene was able to significantly activate AhR, whereas the parent AA, 2-aminofluorene, did not.	Nitrogen	17-18	aryl hydrocarbon receptor	Homo sapiens	95-98
30873691-3	2019	Herein, the successful synthesis of atomically dispersed Pd single-atom catalysts on nitrogen-doped graphene (Pd1 /N-graphene) by a freeze-drying-assisted method is reported.	Nitrogen	85-93	programmed cell death 1	Homo sapiens	110-113
26443077-2	2015	Via reaction with Ag(PF6) under two different conditions, two new 1D coordination polymers were obtained; under a nitrogen atmosphere, the silver ions are connected by argentophilic interactions but under an ambient atmosphere, the silver ions exhibit no interaction between them but coordination to the (H2PO4)(-) ions.	Nitrogen	114-122	sperm associated antigen 17	Homo sapiens	21-24
26524525-6	2015	However, the hydroxyl group of 5hmC and carbonyl group of 5fC face towards the opposite direction because the hydroxymethyl group of 5hmC and formyl group of 5fC adopt restrained conformations through forming hydrogen bonds with the 1-carboxylate of NOG and N4 exocyclic nitrogen of cytosine, respectively.	Nitrogen	271-279	noggin	Homo sapiens	250-253
30873691-5	2019	Importantly, the Pd1 /N-graphene catalyst exhibits excellent durability at the optimal reaction temperature of 125  C, which is explained by the strong local coordination of Pd atoms by nitrogen atoms, which suppresses the Pd aggregation.	Nitrogen	186-194	programmed cell death 1	Homo sapiens	17-20
30636324-7	2019	We also demonstrate that AHK4, the Arabidopsis orthologue of LHK1, is able to regulate M. loti infection in L. japonicus, suggesting that an endogenous cytokinin receptor could be sufficient for engineering nitrogen-fixing root nodule symbiosis in nonlegumes.	Nitrogen	207-215	CHASE domain containing histidine kinase protein	Arabidopsis thaliana	25-29
26540160-5	2015	We found that the loss of Tm7sf2 gene results in significantly reduced blood urea nitrogen levels accompanied by decreased renal inflammatory response and neutral lipid accumulation.	Nitrogen	82-90	transmembrane 7 superfamily member 2	Mus musculus	26-32
31087918-5	2019	The results showed that during the 2015-2016 winter wheat/summer maize season, the nitrate nitrogen from the soil leaching occurred mainly in the summer maize season (rainy season), with the nitrate nitrogen leaching amount reaching 59.9 kg hm-2, while the nitrate nitrogen leaching amount during the winter wheat season was only 2.12 kg hm-2.	Nitrogen	91-99	Putative anthocyanidin reductase	Zea mays	241-245
31087918-5	2019	The results showed that during the 2015-2016 winter wheat/summer maize season, the nitrate nitrogen from the soil leaching occurred mainly in the summer maize season (rainy season), with the nitrate nitrogen leaching amount reaching 59.9 kg hm-2, while the nitrate nitrogen leaching amount during the winter wheat season was only 2.12 kg hm-2.	Nitrogen	91-99	Putative anthocyanidin reductase	Zea mays	338-342
26349566-2	2015	We searched for their metabolites existing in postmortem plasma or urine by LC/Q-TOFMS and were able to detect N-dealkylated metabolites, defluorinated and further oxidized metabolites of MAM-2201, and some hydroxylated metabolites.	Nitrogen	111-112	sarcoglycan gamma	Homo sapiens	188-191
31087918-5	2019	The results showed that during the 2015-2016 winter wheat/summer maize season, the nitrate nitrogen from the soil leaching occurred mainly in the summer maize season (rainy season), with the nitrate nitrogen leaching amount reaching 59.9 kg hm-2, while the nitrate nitrogen leaching amount during the winter wheat season was only 2.12 kg hm-2.	Nitrogen	199-207	Putative anthocyanidin reductase	Zea mays	241-245
31087918-5	2019	The results showed that during the 2015-2016 winter wheat/summer maize season, the nitrate nitrogen from the soil leaching occurred mainly in the summer maize season (rainy season), with the nitrate nitrogen leaching amount reaching 59.9 kg hm-2, while the nitrate nitrogen leaching amount during the winter wheat season was only 2.12 kg hm-2.	Nitrogen	199-207	Putative anthocyanidin reductase	Zea mays	241-245
31087918-8	2019	In summary, the results showed that the nitrate nitrogen leaching values were 10.5, 59.9, and 136.5 kg hm-2 for nitrogen fertilizer applications of 0, 300, and 450 kg hm-2, respectively, during extreme precipitation in a wet year (2015).	Nitrogen	48-56	Putative anthocyanidin reductase	Zea mays	103-107
31087918-8	2019	In summary, the results showed that the nitrate nitrogen leaching values were 10.5, 59.9, and 136.5 kg hm-2 for nitrogen fertilizer applications of 0, 300, and 450 kg hm-2, respectively, during extreme precipitation in a wet year (2015).	Nitrogen	48-56	Putative anthocyanidin reductase	Zea mays	167-171
31087918-9	2019	The value of nitrate nitrogen leaching in the maize season of 2013 (dry year), 2015 (normal year), and 2016 (wet year) accounted for 9%, 10%, and 20% for the 300 kg hm-2 of nitrogen fertilizer applied, respectively.	Nitrogen	21-29	Putative anthocyanidin reductase	Zea mays	165-169
26134167-7	2015	Transcriptomic and metabolomic analyses indicate that the lack of GAPCp activity affects nitrogen and carbon metabolism as well as mineral nutrition and that glycerate and glutamine are the main metabolites responding to GAPCp activity.	Nitrogen	89-97	glyceraldehyde-3-phosphate dehydrogenase C subunit 1	Arabidopsis thaliana	66-71
31087918-9	2019	The value of nitrate nitrogen leaching in the maize season of 2013 (dry year), 2015 (normal year), and 2016 (wet year) accounted for 9%, 10%, and 20% for the 300 kg hm-2 of nitrogen fertilizer applied, respectively.	Nitrogen	173-181	Putative anthocyanidin reductase	Zea mays	165-169
31087918-10	2019	However, the value of nitrate nitrogen leaching in the maize season of 2013 (dry year), 2015 (normal year), and 2016 (wet year) accounted for 11%, 17% and 30% of the 450 kg hm-2 of nitrogen fertilizer applied.	Nitrogen	30-38	Putative anthocyanidin reductase	Zea mays	173-177
30658057-9	2019	Similarly, N-methylation of Leu20 to destabilize the HNP4 dimer had little effect on E. coli killing, but significantly reduced the ability of HNP4 to kill S. aureus, inhibit LF, and bind to LF and gp120.	Nitrogen	11-12	defensin alpha 4	Homo sapiens	53-57
26310141-6	2015	When NO3(-) was the only N source primary root lengths and lateral root numbers were lower in pao2 mutants both without and with exogenous ABA.	Nitrogen	5-6	polyamine oxidase 2	Arabidopsis thaliana	94-98
26345356-1	2015	The X-ray irradiation of binary mixtures of alkyl iodides R-I (R=CH3 , C2 H5 , or i-C3 H7 radicals) and NF3 produces R-NF2 and R-F. Based on calculations performed at the CCSD(T), MRCI(SD+Q), G3B3, and G3 levels of theory, the former product arises from a bimolecular homolytic substitution reaction (SH 2) by the alkyl radicals R, which attack the N atom of NF3 .	Nitrogen	104-105	ring finger protein 2	Homo sapiens	117-122
30658057-9	2019	Similarly, N-methylation of Leu20 to destabilize the HNP4 dimer had little effect on E. coli killing, but significantly reduced the ability of HNP4 to kill S. aureus, inhibit LF, and bind to LF and gp120.	Nitrogen	11-12	defensin alpha 4	Homo sapiens	143-147
30658057-9	2019	Similarly, N-methylation of Leu20 to destabilize the HNP4 dimer had little effect on E. coli killing, but significantly reduced the ability of HNP4 to kill S. aureus, inhibit LF, and bind to LF and gp120.	Nitrogen	11-12	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	198-203
26187957-6	2015	Introduction of the Tn5 transposon into USDA61 resulted in the formation of nitrogen fixation nodules on the roots of soybean cultivar BARC2 (Rj4 Rj4).	Nitrogen	76-84	thaumatin-like protein 1	Glycine max	146-149
26202462-2	2015	The yeast homologue, Sro7, is believed to act as a downstream effector of the Sec4 Rab GTPase to promote soluble N-ethylmaleimide-sensitive factor adaptor protein receptor (SNARE) assembly during Golgi-to-cell surface vesicle transport.	Nitrogen	113-114	Rab family GTPase SEC4	Saccharomyces cerevisiae S288C	78-82
30885746-6	2019	Our study reveals complex molecular interactions between DSG2 mutations and N-glycosylations of desmoglein-2, which may contribute to the molecular understanding of the patho-mechanisms associated with arrhythmogenic right ventricular cardiomyopathy.	Nitrogen	76-77	desmoglein 2	Homo sapiens	96-108
26216646-0	2015	Arabidopsis thaliana ggt1 photorespiratory mutants maintain leaf carbon/nitrogen balance by reducing RuBisCO content and plant growth.	Nitrogen	72-80	glutamate:glyoxylate aminotransferase	Arabidopsis thaliana	21-25
30918251-2	2019	Here, we report atomically dispersed nickel coordinated with nitrogen and sulfur species in porous carbon nanosheets as an electrocatalyst exhibiting excellent activity and durability for OER with a low overpotential of 1.51 V at 10 mA cm-2 and a small Tafel slope of 45 mV dec-1 in alkaline media.	Nitrogen	61-69	deleted in esophageal cancer 1	Homo sapiens	274-279
26218460-4	2015	Several N-methylated analogues are selective and potent agonists or antagonists for hMC1R or hMC5R or have selective antagonist activity for hMC3R.	Nitrogen	8-9	melanocortin 3 receptor	Homo sapiens	141-146
26291458-6	2015	N-linked glycosylation is a post-translational modification that can influence GPCR trafficking, ligand responsiveness and signal output.	Nitrogen	0-1	Trapped in endoderm 1	Drosophila melanogaster	79-83
26271046-6	2015	In the present study, using a series of mutants lacking potential N-glycosylation sites (N256, N370, N406, and N413) within GluA2, we demonstrated that the mutant lacking the N-glycan at N370 strongly suppressed the intracellular trafficking of GluA2 from the endoplasmic reticulum (ER) in HEK293 cells.	Nitrogen	66-67	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	124-129
26179746-2	2015	N-protected 1-aminopyridinium salts are the key compounds and serve as amidyl radical precursors by the action of Ir photocatalysts, fac-[Ir(ppy)3] and [Ir(ppy)2 (dtbbpy)](PF6) (ppy=2-pyridylphenyl, dtbbpy=4,4"-di-tert-butyl-2,2"-bipyridine).	Nitrogen	0-1	sperm associated antigen 17	Homo sapiens	172-175
26245758-9	2015	Renal dysfunction and ultrastructure injury were aggravated in the ApoE/ACE2 DKO mice and Ang II-infused ApoEKO mice with increased plasma levels of creatinine, blood urea nitrogen and enhanced levels of Ang II in plasma and kidneys.	Nitrogen	172-180	angiogenin, ribonuclease, RNase A family, 5	Mus musculus	90-93
26044090-0	2015	ABI1 regulates carbon/nitrogen-nutrient signal transduction independent of ABA biosynthesis and canonical ABA signalling pathways in Arabidopsis.	Nitrogen	22-30	Protein phosphatase 2C family protein	Arabidopsis thaliana	0-4
26276836-3	2015	Here, a combination of transcriptomic and metabolic approaches was performed in salt-treated Arabidopsis thaliana roots, which revealed that the group S1 basic leucine zipper transcription factors bZIP1 and bZIP53 reprogram primary C- and N-metabolism.	Nitrogen	239-240	basic leucine-zipper 1	Arabidopsis thaliana	197-202
26276836-3	2015	Here, a combination of transcriptomic and metabolic approaches was performed in salt-treated Arabidopsis thaliana roots, which revealed that the group S1 basic leucine zipper transcription factors bZIP1 and bZIP53 reprogram primary C- and N-metabolism.	Nitrogen	239-240	basic region/leucine zipper motif 53	Arabidopsis thaliana	207-213
25761782-9	2015	A dramatically different behavior is seen in the presence of N(2) bubbles; EX2 dynamics still take place, but in addition the protein shows EX1 behavior.	Nitrogen	61-62	FERM domain containing 6	Homo sapiens	140-143
26218428-5	2015	Sequence analysis of zebrafish ca10a and ca10b reveals strongly predicted signal peptides, N-glycosylation sites, and a potential disulfide, all of which are conserved, suggesting that all of CARP X and XI are secretory proteins and potentially dimeric.	Nitrogen	91-92	carbonic anhydrase Xa	Danio rerio	31-36
26067028-9	2015	Nitrogen sorption isotherms characterize the mesoporous structures of the materials, and yield BET surface area values and limited BJH pore size distribution curves.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	95-98
25940090-6	2015	The reverse experiment with (15)N-labeled Ca(2+)/CaM demonstrated that the N-terminal Par17 segment binds to both CaM lobes simultaneously, indicating that Ca(2+)/CaM undergoes a conformational change to form a binding channel between its two lobes, apparently similar to the structure of the CaM-smMLCK(796-815) complex.	Nitrogen	32-33	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	Homo sapiens	86-91
25951228-13	2015	The phosphorylation of p38 and ERK1/2 in L4/L5 DRG in the CCI+NS group and the CCI+IMD1-53 group was stronger than that in the Control group or the Sham group; however, the phosphorylation of p38 and ERK1/2 in the CCI+IMD14-47 group was much lower than that in the CCI+NS group or the CCI+IMD1-53 group.	Nitrogen	62-64	mitogen activated protein kinase 14	Rattus norvegicus	23-26
25951228-13	2015	The phosphorylation of p38 and ERK1/2 in L4/L5 DRG in the CCI+NS group and the CCI+IMD1-53 group was stronger than that in the Control group or the Sham group; however, the phosphorylation of p38 and ERK1/2 in the CCI+IMD14-47 group was much lower than that in the CCI+NS group or the CCI+IMD1-53 group.	Nitrogen	62-64	mitogen activated protein kinase 3	Rattus norvegicus	31-37
25951228-13	2015	The phosphorylation of p38 and ERK1/2 in L4/L5 DRG in the CCI+NS group and the CCI+IMD1-53 group was stronger than that in the Control group or the Sham group; however, the phosphorylation of p38 and ERK1/2 in the CCI+IMD14-47 group was much lower than that in the CCI+NS group or the CCI+IMD1-53 group.	Nitrogen	269-271	mitogen activated protein kinase 14	Rattus norvegicus	23-26
25951228-13	2015	The phosphorylation of p38 and ERK1/2 in L4/L5 DRG in the CCI+NS group and the CCI+IMD1-53 group was stronger than that in the Control group or the Sham group; however, the phosphorylation of p38 and ERK1/2 in the CCI+IMD14-47 group was much lower than that in the CCI+NS group or the CCI+IMD1-53 group.	Nitrogen	269-271	mitogen activated protein kinase 3	Rattus norvegicus	31-37
25728785-1	2015	According to the Arg/N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thaliana E3 ligase, PROTEOLYSIS6 (PRT6).	Nitrogen	21-22	proteolysis 6	Arabidopsis thaliana	139-151
25728785-1	2015	According to the Arg/N-end rule pathway, proteins with basic N-termini are targeted for degradation by the Arabidopsis thaliana E3 ligase, PROTEOLYSIS6 (PRT6).	Nitrogen	21-22	proteolysis 6	Arabidopsis thaliana	153-157
25836033-2	2015	The early stability of CSTF-2 is attributable to the influence of temperature; nevertheless, by day 405, the nitrogen removal performed by CSTF-1 increased up to similar values of CSTF-2.	Nitrogen	109-117	cleavage stimulation factor subunit 1	Homo sapiens	139-145
25836033-3	2015	The maximum total nitrogen removal efficiency was 82% in CSTF-1 and 84% in CSTF-2.	Nitrogen	18-26	cleavage stimulation factor subunit 1	Homo sapiens	57-63
25836033-4	2015	After more than 400 days of operation, CSTF-1 and CSTF-2 were capable to attain a total nitrogen removal efficiency of 74+-5% and 78+-4% with a total nitrogen conversion rate of 1.52 and 1.60kg-N/m(sponge)(3)d, respectively.	Nitrogen	88-96	cleavage stimulation factor subunit 1	Homo sapiens	39-45
25836033-4	2015	After more than 400 days of operation, CSTF-1 and CSTF-2 were capable to attain a total nitrogen removal efficiency of 74+-5% and 78+-4% with a total nitrogen conversion rate of 1.52 and 1.60kg-N/m(sponge)(3)d, respectively.	Nitrogen	150-158	cleavage stimulation factor subunit 1	Homo sapiens	39-45
25964983-1	2015	Several new SeF2(CN)2-donor complexes with N or O based donor molecules are reported.	Nitrogen	18-19	transcription factor 4	Homo sapiens	12-16
25772403-6	2015	Experimentally, 1:1 P-bonded PCl3-CH3OH adduct in nitrogen matrix was identified, where shifts in the P-Cl modes of PCl3, O-C, and O-H modes of CH3OH submolecules were observed.	Nitrogen	50-58	PHD finger protein 19	Homo sapiens	29-33
25772403-6	2015	Experimentally, 1:1 P-bonded PCl3-CH3OH adduct in nitrogen matrix was identified, where shifts in the P-Cl modes of PCl3, O-C, and O-H modes of CH3OH submolecules were observed.	Nitrogen	50-58	PHD finger protein 19	Homo sapiens	116-120
25703794-2	2015	Our results suggest that an ionic S(N)2-Si outer-sphere pathway involving the heterolytic cleavage of the Si-H bond competes with the hydride pathway involving the C=N bond inserted into the Re-H bond for the rhenium hydride (1) catalyzed hydrosilylation of the less steric C=N functionalities (phenylmethanimine, PhCH=NH, and N-phenylbenzylideneimine, PhCH=NPh).	Nitrogen	36-37	carboxylesterase 1	Homo sapiens	191-195
25425280-4	2015	EXPERIMENTAL APPROACH: Molecular modelling of CXCR3, followed by virtual ligand docking, highlighted several CXCR3 residues likely to contact either antagonist, notably a conserved aspartate in helix 2 (Asp-112(2:63) ), which was postulated to interact with the quaternary nitrogen of TAK-779.	Nitrogen	273-281	C-X-C motif chemokine receptor 3	Homo sapiens	46-51
25425280-4	2015	EXPERIMENTAL APPROACH: Molecular modelling of CXCR3, followed by virtual ligand docking, highlighted several CXCR3 residues likely to contact either antagonist, notably a conserved aspartate in helix 2 (Asp-112(2:63) ), which was postulated to interact with the quaternary nitrogen of TAK-779.	Nitrogen	273-281	C-X-C motif chemokine receptor 3	Homo sapiens	109-114
25877353-5	2015	The number of CD14+TLR4+ monocytes was positively correlated with estimated glomerular filtration rate (eGFR, P&lt;0.001) and the levels of hematocrit (P&lt;0.01), but negatively correlated with the levels of blood urine nitrogen, serum creatinine, and C-reactive protein (P&lt;0.001 for all), in the CKD patients.	Nitrogen	221-229	CD14 molecule	Homo sapiens	14-18
26240146-2	2015	Detecting hCG N-glycosylation alteration may significantly improve the diagnostic accuracy and sensitivity of related cancers.	Nitrogen	14-15	chorionic gonadotropin subunit beta 5	Homo sapiens	10-13
26240146-4	2015	Here, we report a hydrogen/deuterium exchange and MS approach to investigate the effect of N-glycosylation on the binding of antibodies against different hCG glycoforms.	Nitrogen	91-92	chorionic gonadotropin subunit beta 5	Homo sapiens	154-157
26113157-0	2015	Transgenic poplar expressing the pine GS1a show alterations in nitrogen homeostasis during drought.	Nitrogen	63-71	pseudouridine 5'-phosphatase	Homo sapiens	38-41
26832708-7	2015	And compared to the control group, activity of serum alanine aminotransferase (ALT) and aspartic acid transaminase (AST) decreased significantly in group of paraquat poisoning with triple application of SB, the level of serum urea nitrogen (BUN) and creatinine (Cr) significantly decreased, the difference is statistically significant (P&lt;0.01).	Nitrogen	231-239	glutamic--pyruvic transaminase	Homo sapiens	53-77
26029999-0	2015	Mutation of N-linked glycosylation at Asn548 in CD133 decreases its ability to promote hepatoma cell growth.	Nitrogen	12-13	prominin 1	Homo sapiens	48-53
26029999-4	2015	Here we analyzed the exact site(s) of N-glycosylation in CD133 by mass spectrometry and found that all eight potential N-glycosylation sites of CD133 could be indeed occupied by N-glycans.	Nitrogen	38-39	prominin 1	Homo sapiens	57-62
26029999-4	2015	Here we analyzed the exact site(s) of N-glycosylation in CD133 by mass spectrometry and found that all eight potential N-glycosylation sites of CD133 could be indeed occupied by N-glycans.	Nitrogen	38-39	prominin 1	Homo sapiens	144-149
26029999-4	2015	Here we analyzed the exact site(s) of N-glycosylation in CD133 by mass spectrometry and found that all eight potential N-glycosylation sites of CD133 could be indeed occupied by N-glycans.	Nitrogen	119-120	prominin 1	Homo sapiens	57-62
26029999-4	2015	Here we analyzed the exact site(s) of N-glycosylation in CD133 by mass spectrometry and found that all eight potential N-glycosylation sites of CD133 could be indeed occupied by N-glycans.	Nitrogen	119-120	prominin 1	Homo sapiens	144-149
26279305-1	2015	A conductive catalyst composed of fullerene-structured MoSe2 hollow spheres and highly nitrogen-doped graphene (HNG-MoSe2) was successfully synthesized via a wet chemical process.	Nitrogen	87-95	neurogranin	Homo sapiens	112-115
26279305-4	2015	The superior synergistic effect between the highly nitrogen-doped graphene and the high surface-to-volume ratio MoSe2 hollow spheres afforded the HNG-MoSe2 composite high conductivity and excellent catalytic activity as demonstrated by cyclic voltammetry, electrochemical impedance spectroscopy and Tafel measurements.	Nitrogen	51-59	neurogranin	Homo sapiens	146-149
26172528-1	2015	The two MeCN ligands in [Ru(2-C6H4-2"-Py-kappaC,N)(Phen, trans-C)(MeCN)2]PF6 (1), both trans to a sp(2) hybridized N atom, cannot be substituted by any other ligand.	Nitrogen	11-12	sperm associated antigen 17	Homo sapiens	73-76
26222427-6	2015	Using Ts4 immunoprecipitation combined with liquid chromatography and multiple-stage mass spectrometry, the candidate carbohydrate structure in the Ts4-epitope is proposed to be N-linked fucosylated agalacto-biantennary with bisecting N-acetylglucosamine (GlcNAc) or with N-acetylgalactosamine-GlcNAc motif.	Nitrogen	178-179	Trichinella spiralis resistance 4	Mus musculus	6-9
26222427-6	2015	Using Ts4 immunoprecipitation combined with liquid chromatography and multiple-stage mass spectrometry, the candidate carbohydrate structure in the Ts4-epitope is proposed to be N-linked fucosylated agalacto-biantennary with bisecting N-acetylglucosamine (GlcNAc) or with N-acetylgalactosamine-GlcNAc motif.	Nitrogen	178-179	Trichinella spiralis resistance 4	Mus musculus	148-151
25937236-1	2015	By switching position of the N and S atom in the thiazole ring which were similar to the previously reported agent 5-(4-ethoxyphenyl)-4-(3",4",5"-trimethoxyphenyl)thiazol-2-amine, a series of 4,5-diarylthiazole derivatives were synthesized using Friedel-Crafts reaction based on chemical modification of Combrestatatin A-4 (CA-4).	Nitrogen	29-30	carbonic anhydrase 4	Homo sapiens	304-322
25937236-1	2015	By switching position of the N and S atom in the thiazole ring which were similar to the previously reported agent 5-(4-ethoxyphenyl)-4-(3",4",5"-trimethoxyphenyl)thiazol-2-amine, a series of 4,5-diarylthiazole derivatives were synthesized using Friedel-Crafts reaction based on chemical modification of Combrestatatin A-4 (CA-4).	Nitrogen	29-30	carbonic anhydrase 4	Homo sapiens	324-328
26032909-0	2015	Nitrogen and fluorine dual-doped mesoporous graphene: a high-performance metal-free ORR electrocatalyst with a super-low HO2(-) yield.	Nitrogen	0-8	heme oxygenase 2	Homo sapiens	121-124
25855029-4	2015	Here, we characterized the occupancy and the degree of heterogeneity of individual N-glycosylation sites of clusterin in the plasma of patients diagnosed with localized ccRCC, before and after curative nephrectomy (n = 40).	Nitrogen	83-84	clusterin	Homo sapiens	108-117
26024867-1	2015	The TorC1 protein kinase complex is a central component in a eukaryotic cell"s response to varying nitrogen availability, with kinase activity being stimulated in nitrogen excess by increased intracellular leucine.	Nitrogen	99-107	CREB regulated transcription coactivator 1	Homo sapiens	4-9
26024867-1	2015	The TorC1 protein kinase complex is a central component in a eukaryotic cell"s response to varying nitrogen availability, with kinase activity being stimulated in nitrogen excess by increased intracellular leucine.	Nitrogen	163-171	CREB regulated transcription coactivator 1	Homo sapiens	4-9
26024867-3	2015	Rapamycin inhibition of TorC1 elicits nuclear localization of Gln3, a GATA-family transcription activator responsible for the expression of genes encoding proteins required to transport and degrade poor nitrogen sources, e.g., proline.	Nitrogen	203-211	CREB regulated transcription coactivator 1	Homo sapiens	24-29
25795738-0	2015	ABI1 regulates carbon/nitrogen-nutrient signal transduction independent of ABA biosynthesis and canonical ABA signalling pathways in Arabidopsis.	Nitrogen	22-30	Protein phosphatase 2C family protein	Arabidopsis thaliana	0-4
25790196-6	2015	The sample NPC-2 also exhibits a remarkable selectivity for CO2/N2 separation and a fast adsorption/desorption rate and can be easily regenerated.	Nitrogen	64-66	NPC intracellular cholesterol transporter 2	Homo sapiens	11-16
25719564-1	2015	One-pot multiple borylation of phenylhydrazones to a series of novel boron-nitrogen analogues of benzopentalene by the cleavage of C-H bonds with PhBBr2 mediated by NEt3 has been established.	Nitrogen	75-83	tetraspanin 2	Homo sapiens	165-169
25812480-6	2015	Critical evaluation of the literature data suggests that N/OFQ, acting through the NOP receptor, may cause hypothermia by influencing the complex thermoregulatory system that operates as a federation of independent thermoeffector loops to control body temperature at the hypothalamic level.	Nitrogen	57-58	opioid related nociceptin receptor 1	Rattus norvegicus	83-86
25659749-7	2015	The growth nitrogen regime had a significant effect on the abundance of transcripts encoding vacuolar processing enzymes (VPEs), LN-dependent increases in VPE2 and VPE3 transcripts in all lines.	Nitrogen	11-19	vacuolar processing enzyme 2	Glycine max	155-159
25659749-9	2015	These results show that nitrogen availability regulates the leaf and root cysteine protease, VPE and cystatin transcript profiles in a manner that is in some cases influenced by ectopic OCI expression.	Nitrogen	24-32	vacuolar-processing enzyme	Glycine max	93-96
25803873-0	2015	Calnexin is essential for survival under nitrogen starvation and stationary phase in Schizosaccharomyces pombe.	Nitrogen	41-49	calnexin	Homo sapiens	0-8
25852714-6	2015	Recent studies have revealed that CLE and CEP peptides secreted in the roots are transported to above ground via the xylem in response to plant-microbe interaction and soil nitrogen starvation, respectively.	Nitrogen	173-181	RNA transcription, translation and transport factor	Homo sapiens	34-37
25544388-3	2015	In the current work, human interferon beta (huIFN-beta) was used as a model to identify the potential positions for the addition of new N-glycosylation sites.	Nitrogen	48-49	interferon beta 1	Homo sapiens	27-42
25706562-1	2015	Arabidopsis ubiquitin ligases ATL31 and homologue ATL6 control the carbon/nitrogen nutrient and pathogen responses.	Nitrogen	74-82	carbon/nitrogen insensitive 1	Arabidopsis thaliana	30-35
25519731-6	2015	When goats received a diet rich in nitrogen (N) and nonfiber carbohydrates (NFC), their rumen epithelium had higher levels of UT-B, and the rumen contained higher concentrations of SCFA and NH3-N with a lower pH.	Nitrogen	35-43	urea transporter 1	Capra hircus	126-130
25653109-1	2015	A doubly interpenetrated MOF was constructed using a new pyridyl carboxylate ligand with active pyridyl sites, which exhibits highly efficient luminescence sensing for Cu(2+) ions and sorption selectivities of CO2 over CH4 and N2.	Nitrogen	227-229	lysine acetyltransferase 8	Homo sapiens	25-28
30909444-0	2019	N-Glycomic and Transcriptomic Changes Associated with CDX1 mRNA Expression in Colorectal Cancer Cell Lines.	Nitrogen	0-1	caudal type homeobox 1	Homo sapiens	54-58
25604896-3	2015	The catalysis is fulfilled via the two-step cycle comprising: 1) the reaction of Li2NH and 3d TM(N) to form ternary nitride of LiTMN and H2, and 2) the ammoniation of LiTMN to Li2NH, TM(N) and N2 resulting in the neat reaction of 2 NH3 N2+3 H2.	Nitrogen	193-195	ATP binding cassette subfamily A member 12	Homo sapiens	81-84
25597011-3	2015	A docking study of 15 with our hTRPV1 homology model indicates that there is crucial hydrogen bonding between the ring nitrogen and the receptor, contributing to its potency.	Nitrogen	119-127	transient receptor potential cation channel subfamily V member 1	Homo sapiens	31-37
25311524-9	2015	The results indicate that substitution of sulfur by nitrogen or oxygen in BDT unit, and silicon or phosphor in TT unit of pristine PTB7 leads to a higher eta as well as Deltamuge.	Nitrogen	52-60	endothelin receptor type A	Homo sapiens	154-157
30909444-3	2019	Triggered by our previous study, we here characterized the N-glycomic phenotype of 16 colon cancer cell lines, selected for their differential CDX1 mRNA expression levels.	Nitrogen	59-60	caudal type homeobox 1	Homo sapiens	143-147
30816702-0	2019	MOF-Derived Hybrid Hollow Submicrospheres of Nitrogen-Doped Carbon-Encapsulated Bimetallic Ni-Co-S Nanoparticles for Supercapacitors and Lithium Ion Batteries.	Nitrogen	45-53	lysine acetyltransferase 8	Homo sapiens	0-3
25698922-7	2014	Panx2 was found in intracellular localizations, was partially N-glycosylated, and localizations were non-overlapping with Panx1.	Nitrogen	62-63	pannexin 2	Homo sapiens	0-5
25561468-5	2015	Perturbation of ME ICA512 beta2-strand N-glycosylation upon S508A replacement allows for proICA512 dimerization, O-glycosylation, targeting to granules, and conversion, which are instead precluded upon G553D replacement in the ME ICA512 beta4-strand.	Nitrogen	39-40	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	26-31
25561468-5	2015	Perturbation of ME ICA512 beta2-strand N-glycosylation upon S508A replacement allows for proICA512 dimerization, O-glycosylation, targeting to granules, and conversion, which are instead precluded upon G553D replacement in the ME ICA512 beta4-strand.	Nitrogen	39-40	tubulin beta 3 class III	Homo sapiens	237-242
31057777-0	2019	Cu x Ni y alloy nanoparticles embedded in a nitrogen-carbon network for efficient conversion of carbon dioxide.	Nitrogen	44-52	cut like homeobox 1	Homo sapiens	0-4
25760531-6	2015	High benzydamine N-oxygenation activities of recombinant human FMO1 and FMO3 and human kidney microsomes were observed at pH 8.4, whereas N-demethylation by cytochrome P450 2D6 was faster at pH 7.4.	Nitrogen	17-18	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	63-67
26020752-6	2015	Grass N content was positively related to GE and ME contents but negatively related to grass water-soluble carbohydrates (WSC), NDF, and ADF contents ( &lt; 0.01), indicating that accounting for nutrient interrelations is a crucial aspect of N mitigation.	Nitrogen	6-7	destrin, actin depolymerizing factor	Bos taurus	137-140
31057777-3	2019	Here we prepared for the first time Cu x Ni y alloy nanoparticles embedded in a nitrogen-carbon network.	Nitrogen	80-88	cut like homeobox 1	Homo sapiens	36-40
30830129-0	2019	MOF-derived nitrogen-doped nanoporous carbon for electroreduction of CO2 to CO: the calcining temperature effect and the mechanism.	Nitrogen	12-20	lysine acetyltransferase 8	Homo sapiens	0-3
25512609-10	2015	Furthermore, we show that the deletion of Gln3p and Gat1p transcription factors, which are activated in response to nitrogen availability, led to abnormal LD dynamics.	Nitrogen	116-124	Gat1p	Saccharomyces cerevisiae S288C	52-57
25527290-0	2015	Nitrogen starvation and TorC1 inhibition differentially affect nuclear localization of the Gln3 and Gat1 transcription factors through the rare glutamine tRNACUG in Saccharomyces cerevisiae.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	100-104
25527290-8	2015	The sensitivity of Gln3 localization to glutamine and inhibition of glutamine synthesis prompted us to investigate the effects of a glutamine tRNA mutation (sup70-65) on nitrogen-responsive control of Gln3 and Gat1.	Nitrogen	170-178	Gat1p	Saccharomyces cerevisiae S288C	210-214
25527290-10	2015	However, nuclear Gat1 localization, which also exhibits a glutamine tRNACUG requirement for its response to short-term nitrogen starvation or growth in proline medium or a ure2Delta mutation, does not require tRNACUG for its response to rapamycin.	Nitrogen	119-127	Gat1p	Saccharomyces cerevisiae S288C	17-21
25527290-12	2015	These observations demonstrate the existence of a specific nitrogen-responsive component participating in the control of Gln3 and Gat1 localization and their downstream production of nitrogenous precursors.	Nitrogen	59-67	Gat1p	Saccharomyces cerevisiae S288C	130-134
25527290-14	2015	Our observations also demonstrate distinct mechanistic differences between the responses of Gln3 and Gat1 to rapamycin inhibition of TorC1 and nitrogen starvation.	Nitrogen	143-151	Gat1p	Saccharomyces cerevisiae S288C	101-105
25859101-11	2015	Significant correlation existed between the HbA1c values and both the C: N ratio and average NA in all the three groups.	Nitrogen	73-74	hemoglobin subunit alpha 1	Homo sapiens	44-48
25491884-2	2015	N2 adsorption indicates that they exhibit a stable microporous framework with a BET surface area of 136.78 m(2) g(-1).	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	80-83
30830129-3	2019	Here, we report the MOF-derived nitrogen-doped nanoporous carbon (NC) as a highly efficient and stable electrocatalyst for the conversion of CO2 to CO.	Nitrogen	32-40	lysine acetyltransferase 8	Homo sapiens	20-23
30600443-4	2019	The aim of this study was to elucidate the roles of N-linked glycosylation for the gating properties of the CaV3.1-T-type Ca2+ channel.	Nitrogen	52-53	calcium voltage-gated channel subunit alpha1 G	Homo sapiens	108-114
25540822-6	2015	Together, our approaches identified 40 new SBP ligands, generated experiment-based annotations for 2084 SBPs in 71 isofunctional clusters, and defined numerous metabolic pathways, including novel catabolic pathways for the utilization of ethanolamine as sole nitrogen source and the use of d-Ala-d-Ala as sole carbon source.	Nitrogen	259-267	selenium binding protein 1	Homo sapiens	43-46
30600443-5	2019	N-linked glycosylation synthesis inhibitor tunicamycin causes a reduction of CaV3.1-T-type Ca2+ channel current (CaV3.1-ICa.T) when applied for 12 h or longer.	Nitrogen	0-1	calcium voltage-gated channel subunit alpha1 G	Homo sapiens	77-83
30600443-5	2019	N-linked glycosylation synthesis inhibitor tunicamycin causes a reduction of CaV3.1-T-type Ca2+ channel current (CaV3.1-ICa.T) when applied for 12 h or longer.	Nitrogen	0-1	calcium voltage-gated channel subunit alpha1 G	Homo sapiens	113-119
30600443-9	2019	These findings suggest that N-glycosylation contributes not only to the cell surface expression of the CaV3.1-T-type Ca2+ channel but to the regulation of the gating properties of the channel when the channel proteins were processed during the folding and trafficking steps in the cell.	Nitrogen	28-29	calcium voltage-gated channel subunit alpha1 G	Homo sapiens	103-109
25350655-5	2015	The gas sensor also demonstrated that (3) different gas mixture ratios of CO2 : N2 (100 : 0, 80 : 20, 50 : 50, 20 : 80 and 0 : 100) generated characteristic bubble diameters of 48.95, 77.99, 71.00, 78.53 and 99.50 mum, resulting in a linear coefficient of 10.26 mum (muL s(-1))(-1).	Nitrogen	80-82	tripartite motif containing 37	Homo sapiens	267-270
30718306-1	2019	Sulfoacetaldehyde reductase (IsfD) is a member of the short-chain dehydrogenase/reductase (SDR) family, involved in nitrogen assimilation from aminoethylsulfonate (taurine) in certain environmental and human commensal bacteria.	Nitrogen	116-124	SDR family NAD(P)-dependent oxidoreductase	Klebsiella oxytoca	0-27
25378397-6	2015	Using O-fut1(R245A knock-in) and other gene mutations that abolish the O-fucosylation of N, we found that the monosaccharide O-fucose modification of N has a temperature-sensitive function that is essential for N signaling.	Nitrogen	89-90	O-fucosyltransferase 1	Drosophila melanogaster	6-12
30792397-7	2019	This information can be used to aid in the understanding the impact that nitrogen and phosphorus have on the early summer CyanoHAB and the functional activities of Nostoc- and Anabaena-dominated or Microcystis-dominated communities, and aid in making management decisions related to harmful algal blooms.	Nitrogen	73-81	activation induced cytidine deaminase	Homo sapiens	32-35
25830965-1	2015	A novel organic-inorganic hybrid material, namely L-prol-N-pMCM-41, was synthesized via two steps by covalently anchoring N-functionalized proline derivative (L-prol-N-pTMS) into the pore channels of MCM-41 silica.	Nitrogen	57-58	parathymosin	Homo sapiens	168-172
30633504-0	2019	Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1.	Nitrogen	31-32	ribonuclease A family member 1, pancreatic	Homo sapiens	56-70
26411768-7	2015	Intracellular calcium influx induced by oxidative stress has an significant role in the etiology of bipolar disorders (BDs), and studies recently reported the important role of TRP channels such as TRPC3, TRPM2, and TRPV1 in converting oxidant or nitrogen radical signaling to cytosolic calcium ion homeostasis in BDs.	Nitrogen	247-255	transient receptor potential cation channel subfamily C member 3	Homo sapiens	198-203
30633504-2	2019	RNase 1 contains sequons for N-linked glycosylation at Asn34, Asn76, and Asn88 and is N-glycosylated at all three sites in vivo.	Nitrogen	29-30	ribonuclease A family member 1, pancreatic	Homo sapiens	0-7
26411768-7	2015	Intracellular calcium influx induced by oxidative stress has an significant role in the etiology of bipolar disorders (BDs), and studies recently reported the important role of TRP channels such as TRPC3, TRPM2, and TRPV1 in converting oxidant or nitrogen radical signaling to cytosolic calcium ion homeostasis in BDs.	Nitrogen	247-255	transient receptor potential cation channel subfamily V member 1	Homo sapiens	216-221
30633504-3	2019	The effect of N-glycosylation on the structure and function of RNase 1 is unknown.	Nitrogen	14-15	ribonuclease A family member 1, pancreatic	Homo sapiens	63-70
30633504-6	2019	We found that the N-glycosylation of RNase 1 at any position attenuates its catalytic activity but enhances both its thermostability and its resistance to proteolysis.	Nitrogen	18-19	ribonuclease A family member 1, pancreatic	Homo sapiens	37-44
30645113-4	2019	Structure-activity relationship studies revealed that incorporation of a nitrogen atom into the phenothiazine framework results in increased potency and selectivity for HDAC6 (more than 500-fold selectivity relative to the inhibition of HDAC1, HDAC4, and HDAC8), as rationalized by molecular modeling and docking studies.	Nitrogen	73-81	histone deacetylase 8	Danio rerio	255-260
24840082-0	2015	Dietary protein and urinary nitrogen in relation to 6-year changes in fat mass and fat-free mass.	Nitrogen	28-36	FAT atypical cadherin 1	Homo sapiens	70-73
24840082-0	2015	Dietary protein and urinary nitrogen in relation to 6-year changes in fat mass and fat-free mass.	Nitrogen	28-36	FAT atypical cadherin 1	Homo sapiens	83-86
32830783-6	2019	2NICz (C atom in the 2-position replaced by N) likewise crystallizes in a high-temperature (Pcca, 280 K) polymorph and a low-temperature (P21/c, 150 K) polymorph.	Nitrogen	1-2	propionyl-CoA carboxylase subunit alpha	Homo sapiens	92-96
25061051-5	2015	Using a 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) neurotoxin rodent model of PD, we found that administration of MPTP can reduce expression of endothelial protein C receptor (EPCR), an N-glycosylated type I membrane protein that has the ability to enhance protein C activation.	Nitrogen	198-199	protein C receptor	Homo sapiens	156-186
26457198-6	2015	In this work we studied the temporal order in the induction of AGP1, BAP2, UGA4, and DAL7, genes that are involved in the catabolism and use of leucine, GABA, and allantoin, three poor nitrogen sources.	Nitrogen	185-193	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	63-67
24733517-6	2015	A deletion in ARO8, which encodes an aromatic amino acid transaminase, was found to underlie the transcriptional upregulation of ARO10 during growth, with ammonium sulphate as the sole nitrogen source.	Nitrogen	185-193	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	129-134
29969180-2	2019	Nicotiana benthamiana is widely used for the transient expression of recombinant proteins so it is desirable to modify the endogenous N-glycosylation machinery to allow the synthesis of complex N-glycans lacking beta-1,2-xylose and core alpha-1,3-fucose.	Nitrogen	0-1	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	212-220
25378396-0	2014	Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms.	Nitrogen	119-120	transient receptor potential cation channel subfamily V member 5	Homo sapiens	84-89
30409785-3	2019	Here, following a previous study devoted to Mg2+ binding to nucleobase nitrogens, we surveyed nucleic acid X-ray structures from the PDB with resolutions &lt;=2.9 A to classify the Mg2+ inner-sphere binding patterns to nucleotide carbonyl, ribose hydroxyl, cyclic ether, and phosphodiester oxygen atoms.	Nitrogen	71-80	mucin 7, secreted	Homo sapiens	44-47
25360456-0	2014	Efficient oxygen reduction by nanocomposites of heterometallic carbide and nitrogen-enriched carbon derived from the cobalt-encapsulated indium-MOF.	Nitrogen	75-83	lysine acetyltransferase 8	Homo sapiens	144-147
25360456-1	2014	By one-step pyrolysis of an indium-MOF with entrapped cobalt dimers in the presence of melamine, heterometallic carbide nanoparticles (Co3InC0.75) embedded in nitrogen-enriched carbon have been prepared and found to exhibit efficient electrocatalytic activity for oxygen reduction reaction with high durability and methanol-tolerance properties.	Nitrogen	159-167	lysine acetyltransferase 8	Homo sapiens	35-38
30709282-2	2019	Development of an active and selective N2 electroreduction catalyst requires mechanism determination to aid in connecting the catalyst composition and structure to performance.	Nitrogen	39-41	activation induced cytidine deaminase	Homo sapiens	104-107
25410248-2	2014	Two maize mutant lines (gln1.3 and gln1.4), deficient in two genes encoding cytosolic glutamine synthetase, a key enzyme involved in nitrogen assimilation, were previously characterized by a reduction of kernel size in the gln1.4 mutant and by a reduction of kernel number in the gln1.3 mutant.	Nitrogen	133-141	glutamine synthetase root isozyme 3	Zea mays	24-30
30660106-1	2019	We report here a supercatalyst for oxygen reduction of Pt/CNx/Ni in a unique ternary heterostructure, in which the Pt and the underlying Ni nanoparticles are separated by two to three layers of nitrogen-doped carbon (CNx), which mediates the transfer of electrons from the inner Ni to the outer Pt and protects the Ni against corrosion at the same time.	Nitrogen	194-202	calnexin	Homo sapiens	58-61
25016576-8	2014	Epitope mapping using glycopeptide fragments and in vitro mutagenesis showed that binding of this antibody depends on N-linked glycosylation at asparagine N130 (HXB2 numbering) in the gp120 V1/V2 domain.	Nitrogen	118-119	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	184-189
23894062-8	2014	We showed a SOST peptide (SOST-S146, with homology to a bacterial glycotransferase peptide) binds to a NOG peptide (NOG-N54), which contains a N-glycosylation site.	Nitrogen	103-104	noggin	Homo sapiens	116-119
25188524-1	2014	A nitrogen-doped porous carbon material (N@MOG-C) was prepared by simple pyrolysis of polypyrrole-doped Al-based metal-organic gel (PPy@MOG) at 800  C. The N@MOG-C possessed a uniform three-dimensional (3-D) interconnected mesoporous structure with a high surface area of 1542.6 m(2) g(-1) and a large pore volume of 0.76 cm(3) g(-1).	Nitrogen	2-10	myelin oligodendrocyte glycoprotein	Homo sapiens	43-46
25188524-1	2014	A nitrogen-doped porous carbon material (N@MOG-C) was prepared by simple pyrolysis of polypyrrole-doped Al-based metal-organic gel (PPy@MOG) at 800  C. The N@MOG-C possessed a uniform three-dimensional (3-D) interconnected mesoporous structure with a high surface area of 1542.6 m(2) g(-1) and a large pore volume of 0.76 cm(3) g(-1).	Nitrogen	2-10	myelin oligodendrocyte glycoprotein	Homo sapiens	136-139
25188524-1	2014	A nitrogen-doped porous carbon material (N@MOG-C) was prepared by simple pyrolysis of polypyrrole-doped Al-based metal-organic gel (PPy@MOG) at 800  C. The N@MOG-C possessed a uniform three-dimensional (3-D) interconnected mesoporous structure with a high surface area of 1542.6 m(2) g(-1) and a large pore volume of 0.76 cm(3) g(-1).	Nitrogen	2-10	myelin oligodendrocyte glycoprotein	Homo sapiens	136-139
25188524-3	2014	The doping of nitrogen-endowed N@MOG-C with faster electron transfer kinetics than other carbon materials such as MOG-C, multiwalled carbon nanotubes, and graphene.	Nitrogen	14-22	myelin oligodendrocyte glycoprotein	Homo sapiens	33-36
25188524-3	2014	The doping of nitrogen-endowed N@MOG-C with faster electron transfer kinetics than other carbon materials such as MOG-C, multiwalled carbon nanotubes, and graphene.	Nitrogen	14-22	myelin oligodendrocyte glycoprotein	Homo sapiens	114-117
25232251-3	2014	The N-/O-glycosylation inhibitors (tunicamycin and benzyl-N-acetyl-alpha-galactosaminide) were then used to interfere with KL-6/MUC1 glycosylation in two pancreatic carcinoma cell lines, and the effects on KL-6/MUC1 expression, and cell adhesion and invasion were determined.	Nitrogen	4-5	mucin 1, cell surface associated	Homo sapiens	123-127
25232251-3	2014	The N-/O-glycosylation inhibitors (tunicamycin and benzyl-N-acetyl-alpha-galactosaminide) were then used to interfere with KL-6/MUC1 glycosylation in two pancreatic carcinoma cell lines, and the effects on KL-6/MUC1 expression, and cell adhesion and invasion were determined.	Nitrogen	4-5	mucin 1, cell surface associated	Homo sapiens	128-132
25232251-3	2014	The N-/O-glycosylation inhibitors (tunicamycin and benzyl-N-acetyl-alpha-galactosaminide) were then used to interfere with KL-6/MUC1 glycosylation in two pancreatic carcinoma cell lines, and the effects on KL-6/MUC1 expression, and cell adhesion and invasion were determined.	Nitrogen	4-5	mucin 1, cell surface associated	Homo sapiens	206-210
25232251-3	2014	The N-/O-glycosylation inhibitors (tunicamycin and benzyl-N-acetyl-alpha-galactosaminide) were then used to interfere with KL-6/MUC1 glycosylation in two pancreatic carcinoma cell lines, and the effects on KL-6/MUC1 expression, and cell adhesion and invasion were determined.	Nitrogen	4-5	mucin 1, cell surface associated	Homo sapiens	211-215
25034037-0	2014	Incorporation of heterostructured Sn/SnO nanoparticles in crumpled nitrogen-doped graphene nanosheets for application as anodes in lithium-ion batteries.	Nitrogen	67-75	strawberry notch homolog 1	Homo sapiens	37-40
25034037-1	2014	Sn/SnO nanoparticles are incorporated in crumpled nitrogen-doped graphene nanosheets by a simple melting diffusion method.	Nitrogen	50-58	strawberry notch homolog 1	Homo sapiens	3-6
25169435-5	2014	Extranuclear nucleolin undergoes N- and O-glycosylation, and unlike cytoplasmic nucleolin, membrane-associated nucleolin is not fucosylated.	Nitrogen	33-34	nucleolin	Homo sapiens	13-22
25057024-8	2014	The MPG and MPI programs showed values for ADFI, ADG, G:F, final BW, and nitrogen and phosphorus retention that were similar to those obtained for the 3P feeding program.	Nitrogen	73-81	N-methylpurine DNA glycosylase	Sus scrofa	4-7
24563227-9	2014	Since distinct e-5NT isoforms may derive from different patterns of the enzyme protein N-glycosylation, we speculate that long-term regulation of e-5NT activity in adulthood may be effectuated at posttranslational level and without overall change in the gene and protein expression.	Nitrogen	18-19	5' nucleotidase, ecto	Rattus norvegicus	146-151
25238750-2	2014	The extracellular domain of KOR1 contains eight N-glycosylation sites, N1 to N8, of which only N3 to N7 are highly conserved.	Nitrogen	48-49	glycosyl hydrolase 9A1	Arabidopsis thaliana	28-32
25238750-4	2014	Site-directed mutagenesis analysis of green fluorescent protein (GFP)-KOR1 expressed from its native regulatory sequences established that all eight N-glycosylation sites (N1 to N8) are used in the wild type, whereas stt3a-2 cells could only inefficiently add N-glycans to less conserved sites.	Nitrogen	149-150	glycosyl hydrolase 9A1	Arabidopsis thaliana	70-74
25144769-2	2014	The protein is capable of reducing N-oxygenated structures, but requires cytochrome b5 and cytochrome b5 reductase for electron transfer to catalyze such reactions.	Nitrogen	35-36	cytochrome b5 type A (microsomal)	Mus musculus	73-86
25144769-2	2014	The protein is capable of reducing N-oxygenated structures, but requires cytochrome b5 and cytochrome b5 reductase for electron transfer to catalyze such reactions.	Nitrogen	35-36	cytochrome b5 type A (microsomal)	Mus musculus	91-104
25084947-2	2014	The structural evolutionary behaviors of nitrogen in CsN3 have been studied up to 200 GPa using particle swarm optimization structure search combining with density functional theory.	Nitrogen	41-49	casein kappa	Homo sapiens	53-57
25084947-4	2014	The phase transition to chain like structure (P-1 phase) occurs at a modest pressure 51 GPa, the azide ions N3 (-) (linear chains of three N atoms with covalent bonds and interact weakly with each other) begin to show remarkable polymeric N properties in the CsN3 system.	Nitrogen	108-109	casein kappa	Homo sapiens	259-263
24821112-6	2014	Minipig liver microsomal FMO1 efficiently catalyzed N- and S-oxygenation reactions; in addition, the minipig liver microsomal FMO1 concentration was higher than the levels in rats, humans, and monkeys.	Nitrogen	52-53	flavin containing dimethylaniline monoxygenase 1	Rattus norvegicus	25-29
24847055-1	2014	Nitrogen-responsive control of Gln3 localization is implemented through TorC1-dependent (rapamycin-responsive) and TorC1-independent (nitrogen catabolite repression-sensitive and methionine sulfoximine (Msx)-responsive) regulatory pathways.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	72-77
24847055-1	2014	Nitrogen-responsive control of Gln3 localization is implemented through TorC1-dependent (rapamycin-responsive) and TorC1-independent (nitrogen catabolite repression-sensitive and methionine sulfoximine (Msx)-responsive) regulatory pathways.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	115-120
25052910-2	2014	Nodules are highly organized root organs that form in response to Nod factors produced by rhizobia, and they provide rhizobia with a specialized niche to optimize nutrient exchange and nitrogen fixation.	Nitrogen	185-193	atrophin 1	Homo sapiens	0-3
24799562-4	2014	Here, hydroponically grown Arabidopsis thaliana T-DNA insertional mutants for alternative oxidase (AOX1A) and uncoupling protein (UCP1) fed either NO3 (-) or NH4 (+) were used to determine (i) the response of NO3 (-) uptake and assimilation to the disruption of mAET, and (ii) the interaction of N source (NO3 (-) versus NH4 (+)) and mAET on photosynthetic CO2 assimilation and electron transport.	Nitrogen	51-52	alternative oxidase 2	Arabidopsis thaliana	78-97
24947828-6	2014	The functions of the four validated genes, GCN1, MDS3, ARG81 and BIO3, relate to key roles in nitrogen metabolism and signaling, helping to maintain fermentation performance.	Nitrogen	94-102	Arg81p	Saccharomyces cerevisiae S288C	55-60
24853947-2	2014	The single-crystal X-ray structures reveal that, in paramagnetic and electron paramagnetic resonance active 1 and reported diamagnetic [5]PF6, nearly planar monoanionic HL(-) coordinates to the metal ion via the N,N donors forming a five-membered chelate ring with hydrogen-bonded O-H   O function at the backbone of the ligand framework, as has also been reported in other metal complexes.	Nitrogen	212-213	sperm associated antigen 17	Homo sapiens	138-141
24853947-2	2014	The single-crystal X-ray structures reveal that, in paramagnetic and electron paramagnetic resonance active 1 and reported diamagnetic [5]PF6, nearly planar monoanionic HL(-) coordinates to the metal ion via the N,N donors forming a five-membered chelate ring with hydrogen-bonded O-H   O function at the backbone of the ligand framework, as has also been reported in other metal complexes.	Nitrogen	214-215	sperm associated antigen 17	Homo sapiens	138-141
24806200-2	2014	Structurally, beta-hCG shares a high degree of sequence similarity with beta-hLH, including a common N-glycosylation site at the N-terminus but differs mainly in the presence of an extended C-terminal portion incorporating four closely spaced O-linked glycans.	Nitrogen	101-102	chorionic gonadotropin subunit beta 5	Homo sapiens	19-22
25009769-0	2014	N-glycosylation is required for secretion and enzymatic activity of human hyaluronidase1.	Nitrogen	0-1	hyaluronidase 1	Homo sapiens	74-88
25009769-1	2014	Hyaluronidase1 (HYAL1) is a hydrolytic enzyme that degrades hyaluronic acid (HA) and has three predicted N-glycosylation sites at Asn(99), Asn(216), and Asn(350).	Nitrogen	105-106	hyaluronidase 1	Homo sapiens	0-14
25009769-1	2014	Hyaluronidase1 (HYAL1) is a hydrolytic enzyme that degrades hyaluronic acid (HA) and has three predicted N-glycosylation sites at Asn(99), Asn(216), and Asn(350).	Nitrogen	105-106	hyaluronidase 1	Homo sapiens	16-21
25440717-6	2015	Under natural and N deficiency-induced senescence DUR3 promoter activity was highest in the vasculature, but was also found in surrounding bundle sheath and mesophyll cells.	Nitrogen	18-19	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	50-54
25440717-10	2015	These results indicate that urea can serve as an early metabolic marker for leaf senescence, and that DUR3-mediated urea retrieval contributes to the retranslocation of N from urea during leaf senescence.	Nitrogen	169-170	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	102-106
25567004-4	2015	Unexpectedly, deglycosylated proBHc contained an unexpected pro-peptide of an alpha-factor signal and fortuitous N-linked glycosylation sites in the non-cleaved pro-peptide sequences, but not in the BHc sequences.	Nitrogen	113-114	PHD finger protein 21A	Mus musculus	32-35
27099830-1	2015	BACKGROUND: Dolichyl phosphate-linked mono- and oligosaccharides (DLO) are essential intermediates in protein N-glycosylation, C- and O-mannosylation and GPI anchor biosynthesis.	Nitrogen	8-9	glucose-6-phosphate isomerase	Homo sapiens	127-157
25750673-8	2015	RESULTS: The CIH and CIH+N groups showed increased PEDF gene expression in the temporal cortex, PEDF protein expression remaining unaltered.	Nitrogen	25-26	serpin family F member 1	Rattus norvegicus	51-55
25602335-0	2015	A STELLA Model to Estimate Water and Nitrogen Dynamics in a Short-Rotation Woody Crop Plantation.	Nitrogen	37-45	developmental pluripotency associated 3	Homo sapiens	2-8
25602335-10	2015	This study suggests that the STELLA model developed is a useful tool for estimating water and N dynamics from a woody crop plantation.	Nitrogen	94-95	developmental pluripotency associated 3	Homo sapiens	29-35
26082223-2	2015	It has been proposed that beta-N-acetylglucosaminidase (GlcNAcase), a hexosaminidase in the Golgi membrane which removes a terminal N-acetylglucosamine (GlcNAc), might contribute to simple N-glycosylation profile in several insect cells including Drosophila S2.	Nitrogen	31-32	O-GlcNAcase	Drosophila melanogaster	56-65
25406445-4	2015	At3g45040, designated AtDOK1, complemented defects in the growth and N-linked glycosylation of the S. cerevisiae sec59 mutant, suggesting that AtDOK1 encodes a functional DOK.	Nitrogen	69-70	phosphatidate cytidylyltransferase family protein	Arabidopsis thaliana	22-28
25406445-4	2015	At3g45040, designated AtDOK1, complemented defects in the growth and N-linked glycosylation of the S. cerevisiae sec59 mutant, suggesting that AtDOK1 encodes a functional DOK.	Nitrogen	69-70	phosphatidate cytidylyltransferase family protein	Arabidopsis thaliana	143-149
24644271-2	2014	Expression of NCR-sensitive genes is mediated by two transcription activators, Gln3 and Gat1, in response to provision of a poorly used nitrogen source or following treatment with the TORC1 inhibitor, rapamycin.	Nitrogen	136-144	Gat1p	Saccharomyces cerevisiae S288C	88-92
24718313-1	2014	Tripodal cationic N-donor ligands exhibit sterically controlled self-assembly of tetrahedral M6L4 coordination cages that promote selective anion encapsulation (PF6(-) &gt; OTf(-)) in the solid state.	Nitrogen	18-19	sperm associated antigen 17	Homo sapiens	161-164
24718808-2	2014	It was demonstrated that introducing diamagnetic gases, such as He, CO2, or N2, under STP conditions to the coal surface induces the appearance of a new type of carbon surface radical.	Nitrogen	76-78	sulfotransferase family 1A member 1	Homo sapiens	86-89
30660106-1	2019	We report here a supercatalyst for oxygen reduction of Pt/CNx/Ni in a unique ternary heterostructure, in which the Pt and the underlying Ni nanoparticles are separated by two to three layers of nitrogen-doped carbon (CNx), which mediates the transfer of electrons from the inner Ni to the outer Pt and protects the Ni against corrosion at the same time.	Nitrogen	194-202	calnexin	Homo sapiens	217-220
30659174-4	2019	Here we map the 93-series compound binding site in the GluN1-GluN2B NMDA receptor amino terminal domain and show that the interaction of the N-alkyl group with a hydrophobic cage of the binding site is critical for pH-dependent inhibition.	Nitrogen	58-59	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	61-67
25199249-7	2014	RESULTS &amp; CONCLUSION: We obtained a delta och1 delta alg3 delta mnn1 strain that produces Man5 GlcNAc2 intermediate of human N-glycosylation.	Nitrogen	16-17	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	57-61
24650647-10	2014	The use of the two models SWAP and ANIMO shows the magnitudes of nitrogen and phosphorus fluxes transported by natural and simulated intense rainfall in an agricultural area with different soil management procedures, as required by decision makers.	Nitrogen	65-73	splicing factor SWAP	Homo sapiens	26-30
29946833-1	2019	To recover a nitrogen resource from high-ammonia-nitrogen wastewater, two amphitrophic hydrogen-oxidizing bacteria (HOB), Paracoccus denitrificans Y5 and P. versutus D6, capable of nitrogen assimilation for single-cell protein (SCP) production were isolated.	Nitrogen	13-21	urocortin 3	Homo sapiens	228-231
24685145-0	2014	Structural basis of substrate specificity of human oligosaccharyl transferase subunit N33/Tusc3 and its role in regulating protein N-glycosylation.	Nitrogen	86-87	tumor suppressor candidate 3	Homo sapiens	90-95
26039485-3	2015	N-glycosylation of the cellulase domain was important for KOR1 targeting to and retention within the trans-Golgi network (TGN), and prevented accumulation of KOR1 at tonoplasts.	Nitrogen	0-1	glycosyl hydrolase 9A1	Arabidopsis thaliana	58-62
30720184-9	2019	Furthermore, the high expression of YAP in DN had relevance to increasing systolic blood pressure (SBP) (r=0.484, p=0.019), blood urea nitrogen (BUN) (r=0.522, p=0.032), creatinine (Cr) (r=0.496, p=0.031), progression of DN stage (r=0.647, p=0.001) and progression of DN pathologic classification (r=0.298, p=0.033).	Nitrogen	135-143	Yes1 associated transcriptional regulator	Homo sapiens	36-39
26039485-3	2015	N-glycosylation of the cellulase domain was important for KOR1 targeting to and retention within the trans-Golgi network (TGN), and prevented accumulation of KOR1 at tonoplasts.	Nitrogen	0-1	glycosyl hydrolase 9A1	Arabidopsis thaliana	158-162
24481140-0	2014	[Ru(eta5-C5H5)(eta6-C10H8)]PF6 as a catalyst precursor for the one-pot direct C-H alkenylation of nitrogen heterocycles.	Nitrogen	98-106	sperm associated antigen 17	Homo sapiens	27-30
31527367-10	2019	It is known that increased extracellular glucose levels enhance Cav3.2 activity through asparagine (N)-linked glycosylation of Cav3.2, which might contribute to diabetic neuropathy.	Nitrogen	99-102	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	64-70
24471499-5	2014	Pathway analysis of cancer-associated aberrant glycoproteins revealed an emerging phenomenon that increased activity of N-glycosylation was implicated in several pancreatic cancer pathways, including TGF-beta, TNF, NF-kappa-B, and TFEB-related lysosomal changes.	Nitrogen	120-121	transcription factor EB	Homo sapiens	231-235
25412649-0	2014	Extraordinary N atom tunneling in formation of InN shell layer on GaN nanorod m-plane sidewall.	Nitrogen	14-15	gigaxonin	Homo sapiens	66-69
31527367-10	2019	It is known that increased extracellular glucose levels enhance Cav3.2 activity through asparagine (N)-linked glycosylation of Cav3.2, which might contribute to diabetic neuropathy.	Nitrogen	99-102	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	127-133
25285362-0	2014	Mass spectrometry approach and ELISA reveal the effect of codon optimization on N-linked glycosylation of HIV-1 gp120.	Nitrogen	80-81	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	112-117
24584735-0	2014	Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.	Nitrogen	33-34	synoviolin 1	Homo sapiens	52-56
30648357-7	2019	Conclusion: N-3 supplementation increases muscle atrophy caused by DEXA in an autophagic, AMPK and UPS process.	Nitrogen	12-13	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	90-94
24584735-2	2014	We showed here a post-translational N-glycosylation affected by the HRD1 E3 ubiquitin ligase.	Nitrogen	36-37	synoviolin 1	Homo sapiens	68-72
24584735-5	2014	Pulse chase and mutational analysis indicated that HRD1 inhibits STT3B-dependent post-translational N-glycosylation of ABCG8.	Nitrogen	100-101	synoviolin 1	Homo sapiens	51-55
24584735-6	2014	Whereas, HRD1 had only slight effect on the N-glycosylation status of ABCG5; rather it accelerated ABCG5 degradation in an E3 activity-dependent manner.	Nitrogen	44-45	synoviolin 1	Homo sapiens	9-13
24584735-9	2014	The findings also highlight the unexpected E3 activity-independent role of HRD1 in the regulation of N-glycosylation.	Nitrogen	101-102	synoviolin 1	Homo sapiens	75-79
25450464-7	2014	Also, both TRPV1 agonists induced a loss of mitochondrial membrane potential and an increase of caspase 3/7 activity and production of reactive species of oxygen and nitrogen.	Nitrogen	166-174	transient receptor potential cation channel subfamily V member 1	Homo sapiens	11-16
30565864-2	2019	Herein, flexible Fex Oy /nitrogen-doped carbon films (Fex Oy /NC-MOG) are prepared by facile electrospinning of Fe-based metal-organic gels (MOGs) followed by high-temperature carbonization.	Nitrogen	25-33	myelin oligodendrocyte glycoprotein	Homo sapiens	65-68
25275130-13	2014	We show that N-linked Env glycans display discordant effects on the major events of HIV-1 transmission.	Nitrogen	13-14	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	22-25
24470337-3	2014	Dab2 SBM is overexpressed in bacteria as an isotopically labeled glutathione S-transferase (GST) fusion protein using minimal media containing [15N] ammonium chloride as the nitrogen source.	Nitrogen	174-182	DAB adaptor protein 2	Homo sapiens	0-4
30392659-5	2018	Under the optimized conditions, the ratiometric peak intensity of I2027/I2218 dynamically increased with increasing caspase 3 concentration in the range from 12.5 to 500 ng/mL, with a detection limit of 1.99 ng/mL based on a signal-to-noise ratio of S/N = 3.	Nitrogen	252-253	caspase 3	Rattus norvegicus	116-125
24352227-3	2014	N2 adsorption-desorption studies show that the BET surface area of CuMSC (214-407 m(2) g(-1)) is lower than that of pure silica (611 m(2) g(-1)) and has smaller average pore dimensions (4.0-5.0 nm), both prepared following the same synthetic route.	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	47-50
24398691-4	2014	Two intracellular enzymes, UDP-N-acetylglucosamine-polypeptide beta-N-acetylglucosaminyl transferase (OGT) and O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (OGA), mediate addition and removal, respectively, of N-acetylglucosamine (GlcNAc) from intracellular protein substrates.	Nitrogen	31-32	O-GlcNAcase	Homo sapiens	163-166
24605085-5	2014	In the present study, we provide evidence that TRPM4 and TRPM5 are each N-linked glycosylated at a unique residue, Asn(992) and Asn(932), respectively.	Nitrogen	72-73	transient receptor potential cation channel subfamily M member 5	Homo sapiens	57-62
24605085-11	2014	Altogether, these results demonstrate that TRPM4 and TRPM5 are both N-linked glycosylated at a unique site and also suggest that TRPM4/5 glycosylation seems not to be involved in channel trafficking, but mainly in their functional regulation.	Nitrogen	68-69	transient receptor potential cation channel subfamily M member 5	Homo sapiens	53-58
25324306-8	2014	In short, phosphorylation on novel N-term sites of hnRNPA1 promotes translation of anti-apoptotic proteins and is indispensable for the pro-survival effects of FGF-2.	Nitrogen	35-36	heterogeneous nuclear ribonucleoprotein A1	Homo sapiens	51-58
25195129-5	2014	MAM-2201 and JWH-122 produced common metabolites, N-5-hydroxylated, N-4-hydroxylated and carboxylated JWH-122 metabolites.	Nitrogen	50-51	sarcoglycan gamma	Homo sapiens	0-3
25195129-6	2014	Trace amounts of an N-4-hydroxylated MAM-2201 metabolite, a characteristic MAM-2201 metabolite, was detected in only a few urine specimens from MAM-2201 users.	Nitrogen	20-21	sarcoglycan gamma	Homo sapiens	37-40
25195129-6	2014	Trace amounts of an N-4-hydroxylated MAM-2201 metabolite, a characteristic MAM-2201 metabolite, was detected in only a few urine specimens from MAM-2201 users.	Nitrogen	20-21	sarcoglycan gamma	Homo sapiens	75-78
25195129-6	2014	Trace amounts of an N-4-hydroxylated MAM-2201 metabolite, a characteristic MAM-2201 metabolite, was detected in only a few urine specimens from MAM-2201 users.	Nitrogen	20-21	sarcoglycan gamma	Homo sapiens	75-78
25195129-7	2014	Both in vitro and in vivo studies demonstrated that N-5-hydroxylated JWH-122 metabolite was the primary metabolite of MAM-2201, whereas N-4-hydroxylated JWH-122 metabolite was predominant in JWH-122 metabolism.	Nitrogen	52-53	sarcoglycan gamma	Homo sapiens	118-121
25195129-8	2014	Based on these results, relative concentrations of N-5- and N-4-hydroxylated JWH-122 metabolites should be considered to verify MAM-2201 or JWH-122 users.	Nitrogen	51-52	sarcoglycan gamma	Homo sapiens	128-131
30628399-3	2018	The color and nitrogen removal through an integrated hydrolysis/acidification and anoxic/aerobic (AO) process for the treatment of wastewater containing reactive red 2 (RR2) was investigated.	Nitrogen	14-22	adenosine deaminase RNA specific B2 (inactive)	Homo sapiens	162-167
30266011-2	2018	The synthesized HAp was characterized by the X-ray powder diffraction method, Fourier transform infrared spectroscopy, field emission scanning microscopy, energy-dispersive X-ray spectroscopy, and nitrogen adsorption-desorption isotherms.	Nitrogen	197-205	scaffold attachment factor B	Homo sapiens	16-19
25073740-4	2014	TORC1 inactivation, via nitrogen deprivation or rapamycin treatment, changes cellular levels of SEA complex members.	Nitrogen	24-32	CREB regulated transcription coactivator 1	Homo sapiens	0-5
24449877-0	2014	CLE-CLAVATA1 peptide-receptor signaling module regulates the expansion of plant root systems in a nitrogen-dependent manner.	Nitrogen	98-106	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	4-12
24449877-2	2014	Here we show that a signaling module composed of nitrogen (N)-responsive CLE (CLAVATA3/ESR-related) peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase is expressed in the root vasculature in Arabidopsis thaliana and plays a crucial role in regulating the expansion of the root system under N-deficient conditions.	Nitrogen	49-57	CLAVATA3	Arabidopsis thaliana	78-98
24449877-2	2014	Here we show that a signaling module composed of nitrogen (N)-responsive CLE (CLAVATA3/ESR-related) peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase is expressed in the root vasculature in Arabidopsis thaliana and plays a crucial role in regulating the expansion of the root system under N-deficient conditions.	Nitrogen	49-57	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	117-125
24449877-2	2014	Here we show that a signaling module composed of nitrogen (N)-responsive CLE (CLAVATA3/ESR-related) peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase is expressed in the root vasculature in Arabidopsis thaliana and plays a crucial role in regulating the expansion of the root system under N-deficient conditions.	Nitrogen	49-57	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	127-131
25193509-3	2014	Thus, we tested whether PSCs could be targeted with the nitrogen-containing bisphosphonates (NBP; pamidronate or zoledronic acid), which are potent MML cell inhibitors.	Nitrogen	56-64	corneal susceptibility to P. aeruginosa	Mus musculus	24-28
30358997-8	2018	Finally, N-methyl substituted arginine-containing peptides represent lead compounds for further development of QRFPR agonists.	Nitrogen	9-10	pyroglutamylated RFamide peptide receptor	Homo sapiens	111-116
24700131-11	2014	Using ethanol as carbon source, nitrate (N-NO3(-)) removal efficiency of the bioreactor stood around 80 % for a maximum nitrogen loading rate of approximately 6.5 mg N-NO3 (-) L(-1) h(-1).	Nitrogen	120-128	NNO3	Homo sapiens	41-46
24700131-11	2014	Using ethanol as carbon source, nitrate (N-NO3(-)) removal efficiency of the bioreactor stood around 80 % for a maximum nitrogen loading rate of approximately 6.5 mg N-NO3 (-) L(-1) h(-1).	Nitrogen	120-128	NNO3	Homo sapiens	166-171
24336746-8	2014	Since the ATG31 gene product is required for autophagy, strains expressing the readthrough transcript exhibit defective autophagy induction and reduced fitness under autophagy-inducing nitrogen starvation conditions.	Nitrogen	185-193	Atg31p	Saccharomyces cerevisiae S288C	10-15
30158294-0	2018	An N-Glycosylated Form of SERINC5 Is Specifically Incorporated into HIV-1 Virions.	Nitrogen	3-4	serine incorporator 5	Homo sapiens	26-33
25085507-2	2014	Previous studies in yeast have shown that three GTPases-Gtr1, Gtr2, and Rho1-bind to TORC1 in nitrogen and amino acid starvation conditions to block phosphorylation of the S6 kinase Sch9 and activate protein phosphatase 2A (PP2A).	Nitrogen	94-102	Rho family GTPase RHO1	Saccharomyces cerevisiae S288C	72-76
30158294-6	2018	Sequence alignment of SERINC family proteins led us to identify a conserved N-glycosylation site, N294, in SERINC5.	Nitrogen	26-27	serine incorporator 5	Homo sapiens	107-114
30265270-4	2018	The temperature coefficient of resistance of our films is much greater than the reported values for pristine carbon nanotubes, up to -2.8% K-1 at liquid nitrogen temperature.	Nitrogen	153-161	keratin 1	Homo sapiens	139-142
25137301-2	2014	Nitrogen adsorption/desorption studies showed that the porous carbon featured a BET surface area as high as 310.8 m(2)/g and a rather broad range of pore size from 5 to 80 nm.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	80-83
23917429-4	2014	N-glycosylation of molecules associated with glutamatergic neurotransmission is disrupted in schizophrenia, but it was unknown if these alterations are exclusive to the glutamatergic system or due to a more generalized deficit.In normal human cortex, we found evidence for N-glycosylation of the alpha1, beta1, and beta2 gamma-aminobutyric type A receptor (GABAAR) subunits using deglycosylation protein shift assays.	Nitrogen	0-1	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	315-320
23917429-7	2014	Measures of altered N-glycosylation of the beta1 and beta2 subunits were confounded by an increased apparent molecular mass of all beta1 and beta2 subunit isoforms in schizophrenia.	Nitrogen	20-21	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	53-58
23917429-7	2014	Measures of altered N-glycosylation of the beta1 and beta2 subunits were confounded by an increased apparent molecular mass of all beta1 and beta2 subunit isoforms in schizophrenia.	Nitrogen	20-21	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	141-146
24399238-0	2014	Ubiquitin ligase ATL31 functions in leaf senescence in response to the balance between atmospheric CO2 and nitrogen availability in Arabidopsis.	Nitrogen	107-115	carbon/nitrogen insensitive 1	Arabidopsis thaliana	17-22
24399238-6	2014	In ATL31-overexpressing plants, promotion of senescence under disrupted CO2/N conditions was repressed, whereas in the loss-of-function mutant it was enhanced.	Nitrogen	76-77	carbon/nitrogen insensitive 1	Arabidopsis thaliana	3-8
25089591-9	2014	The Zr(+)/P FLP 4a reacts with PhN S O to give the addition product 13, in which the phosphane Lewis base has added to the nitrogen atom and the Zr(+) Lewis acid to both atoms of the S O unit.	Nitrogen	123-131	carbamoyl-phosphate synthase 1	Homo sapiens	31-34
30335770-5	2018	Averaged across species and conterminous U.S., however, we found that an increase in deposition above current rates of N deposition would coincide with a small net increase in tree growth (1.7% per Delta kg N ha-1 yr-1), and a small net decrease in tree survival (-0.22% per Delta kg N ha-1 yr-1), with substantial regional and among-species variation.	Nitrogen	119-120	solute carrier family 9 member B1	Homo sapiens	207-218
25048616-3	2014	The captodative effect of PLP is balanced by an enzyme active site that controls the deprotonation of both the pyridine nitrogen atom (N1) and the Schiff-base nitrogen atom (N2).	Nitrogen	120-128	pyridoxal phosphatase	Homo sapiens	26-29
25048616-3	2014	The captodative effect of PLP is balanced by an enzyme active site that controls the deprotonation of both the pyridine nitrogen atom (N1) and the Schiff-base nitrogen atom (N2).	Nitrogen	159-167	pyridoxal phosphatase	Homo sapiens	26-29
25144373-0	2014	GlnR negatively regulates the transcription of the alanine dehydrogenase encoding gene ald in Amycolatopsis mediterranei U32 under nitrogen limited conditions via specific binding to its major transcription initiation site.	Nitrogen	131-139	alanine dehydrogenase	Amycolatopsis mediterranei U32	51-72
25144373-2	2014	Under nitrogen-rich conditions, the AlaDH pathway is the major route for ammonium assimilation, while the GS/GOGAT pathway takes over when the extracellular nitrogen supply is limited.	Nitrogen	6-14	alanine dehydrogenase	Amycolatopsis mediterranei U32	36-41
24269589-4	2014	Here, we used a series of synthetic (phospho)peptides derived from the tail to assess phosphorylation-mediated interactions with (15)N-labeled Gal-3 CRD.	Nitrogen	133-134	galectin 3	Homo sapiens	143-148
29894849-1	2018	Pico sized Stannous oxide particles (SnO PPs) were synthesized in an ethanol-water solvent system on the surface of nitrogen doped graphene oxide (GO).	Nitrogen	116-124	strawberry notch homolog 1	Homo sapiens	37-40
25322693-7	2014	RESULTS: Mice upregulated miR-21 had lower plasma levels of blood urea nitrogen (BUN) and creatinine, lower histopathological scores and a decrease in programmed cell death 4 (PDCD4) mRNA and active caspase-3, caspase-8 proteins expressions.	Nitrogen	71-79	microRNA 21a	Mus musculus	26-32
25144373-3	2014	The global nitrogen regulator GlnR was previously characterized to activate the transcription of the GS encoding gene glnA in response to nitrogen limitation and is demonstrated in this study as a repressor for the transcription of the AlaDH encoding gene ald, whose regulation is consistent with the switch of the ammonium assimilation pathways from AlaDH to GS/GOGAT responding to nitrogen limitation.	Nitrogen	11-19	type I glutamate--ammonia ligase	Amycolatopsis mediterranei U32	118-122
25144373-3	2014	The global nitrogen regulator GlnR was previously characterized to activate the transcription of the GS encoding gene glnA in response to nitrogen limitation and is demonstrated in this study as a repressor for the transcription of the AlaDH encoding gene ald, whose regulation is consistent with the switch of the ammonium assimilation pathways from AlaDH to GS/GOGAT responding to nitrogen limitation.	Nitrogen	11-19	alanine dehydrogenase	Amycolatopsis mediterranei U32	236-241
25144373-3	2014	The global nitrogen regulator GlnR was previously characterized to activate the transcription of the GS encoding gene glnA in response to nitrogen limitation and is demonstrated in this study as a repressor for the transcription of the AlaDH encoding gene ald, whose regulation is consistent with the switch of the ammonium assimilation pathways from AlaDH to GS/GOGAT responding to nitrogen limitation.	Nitrogen	11-19	alanine dehydrogenase	Amycolatopsis mediterranei U32	351-356
25144373-3	2014	The global nitrogen regulator GlnR was previously characterized to activate the transcription of the GS encoding gene glnA in response to nitrogen limitation and is demonstrated in this study as a repressor for the transcription of the AlaDH encoding gene ald, whose regulation is consistent with the switch of the ammonium assimilation pathways from AlaDH to GS/GOGAT responding to nitrogen limitation.	Nitrogen	138-146	type I glutamate--ammonia ligase	Amycolatopsis mediterranei U32	118-122
25144373-3	2014	The global nitrogen regulator GlnR was previously characterized to activate the transcription of the GS encoding gene glnA in response to nitrogen limitation and is demonstrated in this study as a repressor for the transcription of the AlaDH encoding gene ald, whose regulation is consistent with the switch of the ammonium assimilation pathways from AlaDH to GS/GOGAT responding to nitrogen limitation.	Nitrogen	138-146	type I glutamate--ammonia ligase	Amycolatopsis mediterranei U32	118-122
25156936-5	2014	Nitrogen balance was also significantly higher in Group Low RFI (20.2 g/d) than in Group High RFI (17.0 g/d).	Nitrogen	0-8	RFI	Bos taurus	60-63
30040982-3	2018	Both GFRA1 and RET are membrane proteins which are N-glycosylated but no O-linked sialylation site on GFRA1 or RET has been reported.	Nitrogen	51-52	GDNF family receptor alpha 1	Homo sapiens	5-10
25156936-5	2014	Nitrogen balance was also significantly higher in Group Low RFI (20.2 g/d) than in Group High RFI (17.0 g/d).	Nitrogen	0-8	RFI	Bos taurus	94-97
24825124-3	2014	Unlike the other known SODs (MnSOD, FeSOD, and (CuZn)SOD), which utilize "typical" biological nitrogen and oxygen donors, NiSOD utilizes a rather unexpected ligand set.	Nitrogen	94-102	superoxide dismutase 2	Homo sapiens	29-34
30185506-3	2018	Deletion of tuberous sclerosis complex 1 (TSC1), an mTORC1 negative regulator, in fibroblasts (Fibro-TSC1-/-) inhibited the elevation of serum creatinine and blood urea nitrogen in AKI compared with that in TSC1fl/fl control mice.	Nitrogen	169-177	TSC complex subunit 1	Mus musculus	12-40
25002233-1	2014	The MDR-involved human GSTA1-1, an important isoenzyme overexpressed in several tumors leading to chemotherapeutic-resistant tumour cells, has been targeted by 2,2"-dihydroxybenzophenones and some of their carbonyl N-analogues, as its potential inhibitors.	Nitrogen	215-216	glutathione S-transferase alpha 1	Homo sapiens	23-30
25040827-2	2014	An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system.	Nitrogen	47-48	prothoracicotropic hormone	Bombyx mori	62-66
25040827-2	2014	An ecdysis progression assay demonstrated that N-glycosylated PTTH exhibited a slightly higher activity than the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system.	Nitrogen	47-48	prothoracicotropic hormone	Bombyx mori	125-129
24477223-7	2014	Univariant and multivariant analysis indicated associations for CYP2B6 g.18492T&gt;C (p &lt; 0.001 and p = 0.001), aspartate aminotransferase (AST; p = 0.001 and p = 0.006) and blood urea nitrogen (BUN; p = 0.011 and p = 0.016) with plasma efavirenz concentration.	Nitrogen	188-196	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	64-70
24202912-8	2014	This is supported by the correlation of N-NO bond reactivity and TRPA1-activating potency in a congeneric series of ABBH N-nitrosamines.	Nitrogen	40-41	transient receptor potential cation channel subfamily A member 1	Homo sapiens	65-70
24337809-7	2014	We further demonstrate using a cell-free pulldown assay that N-glycosylation of the BMPR2-ECD enhances its ability to bind BMP2 ligand but has no impact on binding by the closely-related ACVR2B.	Nitrogen	61-62	bone morphogenetic protein 2	Homo sapiens	123-127
25038634-1	2014	s-heptazine is one of the most attractive polycyclic C-N precursors for graphitic carbon nitride materials (CNx).	Nitrogen	55-56	calnexin	Homo sapiens	108-111
30185506-3	2018	Deletion of tuberous sclerosis complex 1 (TSC1), an mTORC1 negative regulator, in fibroblasts (Fibro-TSC1-/-) inhibited the elevation of serum creatinine and blood urea nitrogen in AKI compared with that in TSC1fl/fl control mice.	Nitrogen	169-177	TSC complex subunit 1	Mus musculus	42-46
30302258-9	2018	Protein-protein interaction analysis revealed a hub protein NEDD8 (CSA009575) which interacted with many regulated genes in spliceosome, nitrogen metabolism, phenylpropanoid biosynthesis, and other pathways.	Nitrogen	137-145	NEDD8 ubiquitin like modifier	Homo sapiens	60-65
24872415-0	2014	N-glycosylation of asparagine 8 regulates surface expression of major histocompatibility complex class I chain-related protein A (MICA) alleles dependent on threonine 24.	Nitrogen	0-1	MHC class I polypeptide-related sequence A	Homo sapiens	130-134
24872415-3	2014	Virus infection and inflammation alter protein N-glycosylation, and we have previously shown that changes in cellular N-glycosylation are involved in regulation of NKG2D ligand surface expression.	Nitrogen	47-48	killer cell lectin like receptor K1	Homo sapiens	164-169
24872415-3	2014	Virus infection and inflammation alter protein N-glycosylation, and we have previously shown that changes in cellular N-glycosylation are involved in regulation of NKG2D ligand surface expression.	Nitrogen	118-119	killer cell lectin like receptor K1	Homo sapiens	164-169
24872415-5	2014	Here we investigated whether direct N-glycosylation of the NKG2D ligand MICA itself is critical for cell surface expression and sought to identify the essential residues.	Nitrogen	36-37	killer cell lectin like receptor K1	Homo sapiens	59-64
24872415-5	2014	Here we investigated whether direct N-glycosylation of the NKG2D ligand MICA itself is critical for cell surface expression and sought to identify the essential residues.	Nitrogen	36-37	MHC class I polypeptide-related sequence A	Homo sapiens	72-76
25763500-2	2014	Our recent study highlights the critical role of a peptide-receptor signaling module composed of nitrogen (N)-responsive CLE peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase in controlling lateral root development in Arabidopsis thaliana.	Nitrogen	97-105	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	142-150
25763500-2	2014	Our recent study highlights the critical role of a peptide-receptor signaling module composed of nitrogen (N)-responsive CLE peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase in controlling lateral root development in Arabidopsis thaliana.	Nitrogen	97-105	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	152-156
25763500-5	2014	The inhibitory action of N-responsive CLE peptides on lateral root development requires the function of CLV1 expressed in phloem companion cells in roots, suggesting that downstream signals are transferred through phloem for systemic regulation of root system architecture.	Nitrogen	25-26	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	104-108
24102742-4	2013	While inside the ER, Rny1p undergoes initial N-linked core glycosylation at four sites, N37, N70, N103 and N123.	Nitrogen	45-46	ribonuclease T2	Saccharomyces cerevisiae S288C	21-26
29882004-6	2018	Strains with loss-of-function in akt-1, akt-2, and sgk-1 had higher resistance to Mn compared to N2 in the survival test.	Nitrogen	97-99	Serine/threonine-protein kinase akt-1	Caenorhabditis elegans	33-38
25006970-2	2014	N-removal over nitrite requires less COD, which is particularly interesting if COD is the limiting parameter for nutrient removal.	Nitrogen	0-1	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	37-40
25006970-2	2014	N-removal over nitrite requires less COD, which is particularly interesting if COD is the limiting parameter for nutrient removal.	Nitrogen	0-1	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	79-82
25009769-2	2014	In this report, we show the functional significance of N-glycosylation on HYAL1 functions.	Nitrogen	55-56	hyaluronidase 1	Homo sapiens	74-79
24098371-10	2013	In conclusion, subsoiling in fallow period, together with N application at 150 kg hm(-2), was beneficial to increase the protein yield and Glu/Gli in grains which improve the quality of wheat.	Nitrogen	58-59	gli	Triticum aestivum	143-146
25009769-3	2014	Using mass spectrometry, we demonstrated that HYAL1 was N-glycosylated at the three asparagine residues.	Nitrogen	56-57	hyaluronidase 1	Homo sapiens	46-51
30004225-3	2018	Enantiomerically pure C, N-unprotected beta2-AAs could be obtained by simple hydrolysis of an isolated favored Ni(II) complex.	Nitrogen	25-26	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	39-44
25009769-4	2014	N-glycosylation of HYAL1 is important for secretion of HYAL1, as demonstrated by site-directed mutation.	Nitrogen	0-1	hyaluronidase 1	Homo sapiens	19-24
30137975-0	2018	Direct Reaction of Nitrogen and Lithium up to 75 GPa: Synthesis of the Li3N, LiN, LiN2, and LiN5 Compounds.	Nitrogen	19-27	calcium/calmodulin dependent serine protein kinase	Homo sapiens	82-86
25009769-4	2014	N-glycosylation of HYAL1 is important for secretion of HYAL1, as demonstrated by site-directed mutation.	Nitrogen	0-1	hyaluronidase 1	Homo sapiens	55-60
25009769-6	2014	Thus, HYAL1 is N-glycosylated at the three asparagine residues, and its secretion and enzymatic activity are regulated by N-glycosylation.	Nitrogen	15-16	hyaluronidase 1	Homo sapiens	6-11
25009769-6	2014	Thus, HYAL1 is N-glycosylated at the three asparagine residues, and its secretion and enzymatic activity are regulated by N-glycosylation.	Nitrogen	122-123	hyaluronidase 1	Homo sapiens	6-11
23935103-1	2013	Five different physiological conditions have been used interchangeably to establish the sequence of molecular events needed to achieve nitrogen-responsive down-regulation of TorC1 and its subsequent regulation of downstream reporters: nitrogen starvation, methionine sulfoximine (Msx) addition, nitrogen limitation, rapamycin addition, and leucine starvation.	Nitrogen	135-143	CREB regulated transcription coactivator 1	Homo sapiens	174-179
23935103-1	2013	Five different physiological conditions have been used interchangeably to establish the sequence of molecular events needed to achieve nitrogen-responsive down-regulation of TorC1 and its subsequent regulation of downstream reporters: nitrogen starvation, methionine sulfoximine (Msx) addition, nitrogen limitation, rapamycin addition, and leucine starvation.	Nitrogen	235-243	CREB regulated transcription coactivator 1	Homo sapiens	174-179
23935103-1	2013	Five different physiological conditions have been used interchangeably to establish the sequence of molecular events needed to achieve nitrogen-responsive down-regulation of TorC1 and its subsequent regulation of downstream reporters: nitrogen starvation, methionine sulfoximine (Msx) addition, nitrogen limitation, rapamycin addition, and leucine starvation.	Nitrogen	235-243	CREB regulated transcription coactivator 1	Homo sapiens	174-179
23983068-7	2013	Furthermore, the specialized structure of the present multifunctional N,O,P ligand L1 or L4, and the corresponding mechanistic study of the copper catalyst system were investigated by 31P NMR spectroscopy, circular dichroism (CD), and UV/Vis absorption.	Nitrogen	70-71	ribosomal protein L4	Homo sapiens	74-91
24676352-10	2014	Levels of CTGF were negatively correlated with the estimated glomerular filtration rate (eGFR) and the methylation level of the promoter, while they were positively correlated with age, urinary albumin-to-creatinine ratio (UACR), blood urea nitrogen, creatinine, fasting blood sugar and postprandial blood glucose.	Nitrogen	241-249	cellular communication network factor 2	Homo sapiens	10-14
24910636-10	2014	These observations indicate that AMT1.1 may play additional roles that affect N uptake and plant immune responses.	Nitrogen	78-79	ammonium transporter 1;1	Arabidopsis thaliana	33-39
23752476-1	2013	DFT studies have been carried out to investigate the role of nitrogen participation in the interring haptotropic rearrangements of [(eta(6)-C6H5)(C6H4-4-NH2)]Cr(CO)3 and [(eta(6)-C6H5)(C6H4-2-NH2)]Cr(CO)3.	Nitrogen	61-69	endothelin receptor type A	Homo sapiens	133-136
25199249-11	2014	Our results demonstrate that delta och1 delta alg3 deltamnn1 triple mutant can be used as an initial strain to construct an yeast therapeutic glycoprotein-expression system by introducing various enzymes that are involved in human N-glycosylation pathway.	Nitrogen	231-232	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	46-50
23752476-1	2013	DFT studies have been carried out to investigate the role of nitrogen participation in the interring haptotropic rearrangements of [(eta(6)-C6H5)(C6H4-4-NH2)]Cr(CO)3 and [(eta(6)-C6H5)(C6H4-2-NH2)]Cr(CO)3.	Nitrogen	61-69	endothelin receptor type A	Homo sapiens	172-175
30181442-7	2018	The studied compound was docked to the novel X-ray structure of the human dopamine D2 receptor in the inactive state (PDB ID: 6CM4) and established the main contact between its protonatable nitrogen atom and Asp (3.32) of the receptor.	Nitrogen	190-198	dopamine receptor D2	Homo sapiens	74-94
29778083-9	2018	The characters of biofilms distributed in different sections inside MSL-1 system well illustrated the nitrogen removal mechanism inside MSL systems.	Nitrogen	102-110	MSL complex subunit 1	Homo sapiens	68-73
24631513-3	2014	In the current study, we found that the replacement of the 2-hydrogen atom (H) or N-methyl group (CH3) by the butyl group (C4C9) caused the more than 3-fold potent cytotoxic effects on cells transformed by the JAK2 V617F mutant.	Nitrogen	82-83	Janus kinase 2	Homo sapiens	210-214
24528491-9	2014	Several cytokinin metabolites, in particular cis-zeatin (cZ) and N-glucoside cytokinins, were depleted stronger in 35S:CKX7 plants compared with plants overexpressing other CKX genes.	Nitrogen	65-66	cytokinin oxidase 7	Arabidopsis thaliana	119-123
30059870-9	2018	The nitrate reductase and urease activities decreased with the increasing Al concentration, indicating that nitrogen metabolism was halted.	Nitrogen	108-116	chalcone reductase CHR1	Glycine max	12-21
30090890-0	2018	SnS2/TiO2 nanohybrids chemically bonded on nitrogen-doped graphene for lithium-sulfur batteries: synergy of vacancy defects and heterostructures.	Nitrogen	43-51	sodium voltage-gated channel alpha subunit 11	Homo sapiens	0-4
24772938-5	2014	HsIil0 experiencing minimum decline in enzyme activities and best possible nitrogen regulation under NaC1 replete condition showed adequate nutritional management.	Nitrogen	75-83	nucleus accumbens associated 1	Homo sapiens	101-105
24243557-7	2014	Transcript analysis of genes involved in N-glycosylation showed a 17% decrease in expression levels of DPM1, a subunit of the dolichol-phosphate-mannose synthase, and an 8% increase in RPN2, a subunit of the oligosaccharyl transferase.	Nitrogen	41-42	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	103-107
24243557-7	2014	Transcript analysis of genes involved in N-glycosylation showed a 17% decrease in expression levels of DPM1, a subunit of the dolichol-phosphate-mannose synthase, and an 8% increase in RPN2, a subunit of the oligosaccharyl transferase.	Nitrogen	41-42	ribophorin II	Homo sapiens	185-189
30090890-2	2018	Herein, we demonstrate a synergetic vacancy and heterostructure engineering strategy using a nitrogen-doped graphene/SnS2/TiO2 (denoted as NG/SnS2/TiO2) nanocomposite to enhance the electrochemical performance of LSBs.	Nitrogen	93-101	sodium voltage-gated channel alpha subunit 11	Homo sapiens	117-121
30090890-2	2018	Herein, we demonstrate a synergetic vacancy and heterostructure engineering strategy using a nitrogen-doped graphene/SnS2/TiO2 (denoted as NG/SnS2/TiO2) nanocomposite to enhance the electrochemical performance of LSBs.	Nitrogen	93-101	sodium voltage-gated channel alpha subunit 11	Homo sapiens	142-146
24607031-8	2014	NF-kappaB p65 levels in urinary sediment cells showed a significant positive correlation with serum Cr (Day 0: rs=0.792; p &lt;0.001, Day 7: rs=0.605; p &lt;0.001) and blood urea nitrogen (BUN) (Day 0: rs=0.839; p &lt;0.001, Day 7: rs=0.596; p &lt;0.001).	Nitrogen	179-187	RELA proto-oncogene, NF-kB subunit	Homo sapiens	10-13
30186302-6	2018	PH-treated plants grown with lower N availability showed reduced expression of NR and NiR as well as of nitrate and ammonium transporter transcripts in both leaf and root tissues in comparison with untreated plants; this was especially pronounced after application of PH by substrate drench.	Nitrogen	35-36	ferredoxin--nitrite reductase, chloroplastic	Solanum lycopersicum	86-89
24434189-0	2014	A novel fluorometric assay for aldo-keto reductase 1C3 predicts metabolic activation of the nitrogen mustard prodrug PR-104A in human leukaemia cells.	Nitrogen	92-100	aldo-keto reductase family 1 member C3	Homo sapiens	31-54
30103455-0	2018	Nitrogen Supply and Leaf Age Affect the Expression of TaGS1 or TaGS2 Driven by a Constitutive Promoter in Transgenic Tobacco.	Nitrogen	0-8	glutathione synthetase, chloroplastic	Triticum aestivum	54-59
24361341-9	2014	Taken together, these data identify the two specific sites of N-linked glycosylation of murine NOX1 and demonstrate that they are not required for normal enzyme activity, protein stability, and membrane trafficking.	Nitrogen	62-63	NADPH oxidase 1	Mus musculus	95-99
30103455-4	2018	Under nitrogen-sufficient conditions, the leaves of GS2-TR showed high accumulation of the TaGS2 transcript, while those of GS1-TR showed a low TaGS1 transcript levels.	Nitrogen	6-14	glutathione synthetase, chloroplastic	Triticum aestivum	124-127
30103455-5	2018	However, compared with nitrogen-sufficient conditions, the TaGS1 transcript level increased in the leaves under nitrogen starvation, but the TaGS2 transcript level decreased.	Nitrogen	112-120	glutathione synthetase, chloroplastic	Triticum aestivum	59-64
30103455-6	2018	In addition, the TaGS1 and TaGS2 transcript levels were highest in the middle leaves under nitrogen-sufficient and starvation conditions.	Nitrogen	91-99	glutathione synthetase, chloroplastic	Triticum aestivum	17-22
30103455-8	2018	Additionally, in regard to nitrogen metabolism level, the lower leaves of the GS1-TR exhibited lower NH4+ and higher amino acid contents, while the upper leaves exhibited higher amino acid, soluble protein and chlorophyll contents.	Nitrogen	27-35	glutathione synthetase, chloroplastic	Triticum aestivum	78-81
24307706-2	2014	Spaca7 transcripts are detected only in testis and predict a 158-residue mature polypeptide with one potential N-glycosylation site and no cysteines.	Nitrogen	111-112	sperm acrosome associated 7	Mus musculus	0-6
24400928-0	2014	Complexes possessing rare "tertiary" sulfonamide nitrogen-to-metal bonds of normal length: fac-[Re(CO)3(N(SO2R)dien)]PF6 complexes with hydrophilic sulfonamide ligands.	Nitrogen	49-57	sperm associated antigen 17	Homo sapiens	117-120
30103455-10	2018	Given the role that GS isoforms play in nitrogen metabolism, these data suggest that TaGS1 overexpression may improve nitrogen transport, and that TaGS2 overexpression may improve nitrogen assimilation under nitrogen stress.	Nitrogen	118-126	glutathione synthetase, chloroplastic	Triticum aestivum	85-90
24365146-0	2014	N-Linked glycosylation of the superoxide-producing NADPH oxidase Nox1.	Nitrogen	0-1	NADPH oxidase 1	Homo sapiens	65-69
30103455-10	2018	Given the role that GS isoforms play in nitrogen metabolism, these data suggest that TaGS1 overexpression may improve nitrogen transport, and that TaGS2 overexpression may improve nitrogen assimilation under nitrogen stress.	Nitrogen	118-126	glutathione synthetase, chloroplastic	Triticum aestivum	85-90
30103455-10	2018	Given the role that GS isoforms play in nitrogen metabolism, these data suggest that TaGS1 overexpression may improve nitrogen transport, and that TaGS2 overexpression may improve nitrogen assimilation under nitrogen stress.	Nitrogen	118-126	glutathione synthetase, chloroplastic	Triticum aestivum	85-90
30030497-5	2018	Using a mouse model of angiotensin II (Ang II)-induced renal damage, we demonstrate that PI3Kgamma inhibitor AS605240 effectively mitigates Ang II-induced increases in serum creatinine and blood urea nitrogen, renal interstitial collagen deposition, the accumulation of ECM proteins and the expression of alpha-Sma and fibrosis-related genes in vivo.	Nitrogen	200-208	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma	Mus musculus	89-98
24125761-0	2014	N-Glycosylation during translation is essential for human arylacetamide deacetylase enzyme activity.	Nitrogen	0-1	arylacetamide deacetylase	Homo sapiens	58-83
24125761-12	2014	Overall, this study found that the translational, but not post-translational, N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.	Nitrogen	78-79	arylacetamide deacetylase	Homo sapiens	97-102
24125761-12	2014	Overall, this study found that the translational, but not post-translational, N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.	Nitrogen	78-79	arylacetamide deacetylase	Homo sapiens	138-143
29457375-0	2018	Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjogren"s Syndrome.	Nitrogen	85-86	B cell linker	Homo sapiens	33-50
24403138-11	2014	These combined results demonstrate that acute stress increases N/OFQ systems in the CeA and that N/OFQ has antistress properties.	Nitrogen	63-64	carcinoembryonic antigen gene family 4	Rattus norvegicus	84-87
29779877-6	2018	This silencing activity is independent of Eph receptors and involves a N-glycosylation site (N-139) in the extracellular domain of Ephrin-B1.	Nitrogen	71-72	ephrin B1	Homo sapiens	131-140
24326275-1	2014	To cope with developing pest resistance and ecological problems associated with conventional insecticides and to search for potent insecticides targeting at ryanodine receptor (RyR), a series of novel anthranilic diamides containing N-substitued nitrophenylpyrazole were designed and synthesized.	Nitrogen	233-234	ryanodine receptor	Plutella xylostella	177-180
29779877-6	2018	This silencing activity is independent of Eph receptors and involves a N-glycosylation site (N-139) in the extracellular domain of Ephrin-B1.	Nitrogen	93-94	ephrin B1	Homo sapiens	131-140
23836015-5	2014	ALD3 deletion strain overexpressing ARO9 and ARO10 both by episomal overexpression and by induction of the endogenous genes through overexpression of Aro80 transcription factor, produced 4.8 g/L 2-PE in a medium containing 10 g/L L-phenylalanine as a sole nitrogen source.	Nitrogen	256-264	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	45-50
29747513-4	2018	The copolymer interacts with miR-34a at low N/P ratios (~2/1) to form nanoplexes of size ~108 nm and a zeta potential ~ +39 mV.	Nitrogen	44-45	microRNA 34a	Homo sapiens	29-36
25229868-6	2014	The interaction with Cne1p was abrogated by the addition of tunicamycin, an inhibitor of N-glycosylation, indicating that N-linked carbohydrates might be necessary for protein binding to Cne1p.	Nitrogen	89-90	calnexin	Saccharomyces cerevisiae S288C	21-26
29512823-0	2018	Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: Implications for B-cell selection.	Nitrogen	16-17	proteinase 3	Homo sapiens	98-102
25229868-6	2014	The interaction with Cne1p was abrogated by the addition of tunicamycin, an inhibitor of N-glycosylation, indicating that N-linked carbohydrates might be necessary for protein binding to Cne1p.	Nitrogen	89-90	calnexin	Saccharomyces cerevisiae S288C	187-192
24910237-3	2014	The metabolic pathways examined were the CYP1A2-catalyzed tacrine 1-hydroxylation, CYP2B6-catalyzed bupropion hydroxylation, CYP2C8-catalyzed amodiaquine N-deethylation, CYP2C9- catalyzed diclofenac 4"-hydroxylation, CYP2D6-catalyzed dextromethorphan O-demethylation, and CYP3A4-catalyzed midazolam 1"-hydroxylation.	Nitrogen	154-155	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	125-131
29512823-5	2018	When normalized for SHM, ACPA still had significantly higher frequency of N-linked motifs compared to all studied mAbs including highly mutated HIV broadly-neutralizing and malaria-associated mAbs.	Nitrogen	74-75	proteinase 3	Homo sapiens	25-29
24567814-7	2014	RESULTS: In comparison to the control group, the NP + NS group showed a significant increase of phospho-p38 and p38 MAPK, as well as of the proinflammatory cytokines, tumor necrosis factor alpha (TNFalpha), and intercellular adhesion molecule 1 (ICAM1).	Nitrogen	54-56	mitogen activated protein kinase 14	Rattus norvegicus	104-107
24567814-7	2014	RESULTS: In comparison to the control group, the NP + NS group showed a significant increase of phospho-p38 and p38 MAPK, as well as of the proinflammatory cytokines, tumor necrosis factor alpha (TNFalpha), and intercellular adhesion molecule 1 (ICAM1).	Nitrogen	54-56	mitogen activated protein kinase 14	Rattus norvegicus	112-115
29547901-6	2018	Regarding the latter, we show that the 55 kDa N-glycosylated hNOT-1/ALG3-1 molecule binds the N-glycosylated CREB3 precursor but does not interact with CREB3"s proteolytic products specific to the endoplasmic reticulum and to the nucleus.	Nitrogen	46-47	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	68-72
24056255-3	2013	We have demonstrated the application of this system to obtain N-formylated form of a mycobacterial secretory protein ESAT-6 which is an important target for T-cell recognition during Mycobacterium tuberculosis infection.	Nitrogen	62-63	ESAT-6 protein EsxA	Mycobacterium tuberculosis H37Rv	117-123
23792024-4	2013	Six isoenzymes (CerS1-6) catalyze the N-acylation of the sphingoid bases, albeit with strictly acyl-Coenzyme A (CoA) chain length specificity.	Nitrogen	38-39	ceramide synthase 1	Mus musculus	16-21
29547901-6	2018	Regarding the latter, we show that the 55 kDa N-glycosylated hNOT-1/ALG3-1 molecule binds the N-glycosylated CREB3 precursor but does not interact with CREB3"s proteolytic products specific to the endoplasmic reticulum and to the nucleus.	Nitrogen	62-63	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	68-72
23922845-7	2013	Fourteen tryptic peptides of both human APE1 (hAPE1) and (15)N-labeled hAPE1 were identified following trypsin digestion.	Nitrogen	61-62	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	71-76
23799889-4	2013	Because of the high Brunauer, Emmett, and Teller (BET) nitrogen sorption surface area of 318 m(2) g(-1) and large pore volume, this sample displays a maximum discharge specific capacity of 1788.9 F g(-1) at a discharge current density of 0.5 A g(-1).	Nitrogen	55-63	delta/notch like EGF repeat containing	Homo sapiens	50-53
24163377-5	2013	TGA-MS and FTIR spectroscopy allowed the qualitative identification of recalcitrant nitrogen-containing compounds in the pre-treated poultry sample, produced by Maillard reactions.	Nitrogen	84-92	T-box transcription factor 1	Homo sapiens	0-3
24240982-4	2013	The kinetic current density of N-Pt3Fe1/C as normalized by ECSA is still as high as 0.145 mA cm(-2) and only 7% loss after 20,000 potential cycles from 0.6 to 1.2 V (vs. NHE) in O2-bubbling perchloric acid solution, whereas Pt3Fe1/C shows 49% loss under the same tests.	Nitrogen	31-32	solute carrier family 9 member C1	Homo sapiens	170-173
29532326-8	2018	Combining all this data provides a detailed specification of co-occurring C8 proteoforms, including experimental evidence on N-glycosylation, C-mannosylation, and O-glycosylation.	Nitrogen	125-126	homeobox C8	Homo sapiens	74-76
24072041-7	2013	Defective N-glycosylation of TbetaRII further suppressed the TGF-beta1-binding to TbetaRII, thereby decreasing TGF-beta signaling.	Nitrogen	10-11	transforming growth factor beta receptor 2	Homo sapiens	29-37
24072041-7	2013	Defective N-glycosylation of TbetaRII further suppressed the TGF-beta1-binding to TbetaRII, thereby decreasing TGF-beta signaling.	Nitrogen	10-11	transforming growth factor beta receptor 2	Homo sapiens	82-90
23688541-6	2013	The expression levels of tyrosine hydroxylase (TH), dopamine transporter (DAT) and vesicular monoamine transporter 2(VMAT-2) were significantly decreased and the activity/levels of reactive oxygen species (ROS), nitric oxide synthase (NOS) and nitrogen (NO) were notably increased after METH treatment.	Nitrogen	244-252	solute carrier family 18 member A2	Homo sapiens	117-123
29532326-9	2018	In addition to the known N-glycosylation sites, two more N-glycosylation sites were detected on C8.	Nitrogen	57-58	homeobox C8	Homo sapiens	96-98
23541506-4	2013	This paper describes a comparative study of the thermodynamics of unmodified and modified Tat peptide interaction with TAR RNA, where the peptide is methylated at epsilon (e) and eta (eta) nitrogen atoms of guanidinium group of arginine side chain at position 52 or 53.	Nitrogen	189-197	endothelin receptor type A	Homo sapiens	179-182
29627732-11	2018	First one is the drought-dependent induction in sugar and protein transporters genes (SWEET and NRT1/PTR) in the roots of 110R to facilitate carbohydrate and nitrogen accumulation.	Nitrogen	158-166	immunoglobulin superfamily member 9	Homo sapiens	96-100
23541506-4	2013	This paper describes a comparative study of the thermodynamics of unmodified and modified Tat peptide interaction with TAR RNA, where the peptide is methylated at epsilon (e) and eta (eta) nitrogen atoms of guanidinium group of arginine side chain at position 52 or 53.	Nitrogen	189-197	endothelin receptor type A	Homo sapiens	184-187
23541506-6	2013	In contrast, monomethylation of arginine residue at eta nitrogen results in reduced binding affinity originating exclusively from a less favourable enthalpy change leaving entropic component unaffected.	Nitrogen	56-64	endothelin receptor type A	Homo sapiens	52-55
24058148-1	2013	Cytokinin activity in plants is closely related to nitrogen availability, and an Arabidopsis gene for adenosine phosphate-isopentenyltransferase (IPT), IPT3, is regulated by inorganic nitrogen sources in a nitrate-specific manner.	Nitrogen	51-59	isopentenyltransferase 3	Arabidopsis thaliana	152-156
24058148-1	2013	Cytokinin activity in plants is closely related to nitrogen availability, and an Arabidopsis gene for adenosine phosphate-isopentenyltransferase (IPT), IPT3, is regulated by inorganic nitrogen sources in a nitrate-specific manner.	Nitrogen	184-192	isopentenyltransferase 3	Arabidopsis thaliana	152-156
29898548-1	2018	The parent activated carbon (ACP) was modified with urea and thiourea to obtain N-doped activated carbon (ACN) and N, S co-doped activated carbon (ACNS), respectively.	Nitrogen	80-81	CPAT1	Homo sapiens	29-32
23918223-5	2013	The formation of a Ga-N(CH3)(CH2CH3) bond during the ALD of HfO2 using TEMAH as the reactant without breaking the Hf-N bond could be the key part of the mechanism behind the formation of an interface layer at the HfO2/GaN interface.	Nitrogen	22-23	gigaxonin	Homo sapiens	218-221
23564016-1	2013	Nitrogen-containing bisphosphonates have been well known to be inhibited farnesyl diphosphate synthase (FDPS), an enzyme in mevalonic acid metabolism, resulting in disturbance in polymerization of cytoskeleton structure in bone resorption and promotion of apoptosis in mature osteoclasts.	Nitrogen	0-8	farnesyl diphosphate synthetase	Mus musculus	73-102
23564016-1	2013	Nitrogen-containing bisphosphonates have been well known to be inhibited farnesyl diphosphate synthase (FDPS), an enzyme in mevalonic acid metabolism, resulting in disturbance in polymerization of cytoskeleton structure in bone resorption and promotion of apoptosis in mature osteoclasts.	Nitrogen	0-8	farnesyl diphosphate synthetase	Mus musculus	104-108
23564016-12	2013	These results suggest that nitrogen-containing bisphosphonates suppress the activity of osteoclastic acid-activated Cl(-) currents through FDPS inhibition, suggesting the inhibition of Cl(-) extrusion activity.	Nitrogen	27-35	farnesyl diphosphate synthetase	Mus musculus	139-143
29896207-5	2018	Here, we characterized the function of CrFAP89, a flagella-associated WDR-containing protein, which was identified from C. reinhardtii nitrogen deficiency transcriptome analysis.	Nitrogen	135-143	uncharacterized protein	Chlamydomonas reinhardtii	39-46
23957201-6	2013	The activation of ERK and p38 was down-regulated when rats were exposed to normoxic hyperbaric nitrogen for 10 hours.	Nitrogen	95-103	mitogen activated protein kinase 14	Rattus norvegicus	26-29
23731343-6	2013	Mutation of this motif to mimic SIPK phosphorylation leads to an increased proportion of cells displaying SGT1 nuclear accumulation and impairs N-mediated resistance to TMV, as does phospho-null substitution at the same residue.	Nitrogen	144-145	mitogen-activated protein kinase homolog NTF4-like	Nicotiana tabacum	32-36
29896207-6	2018	Quantitative real time-PCR showed that the transcription levels of CrFAP89 were significantly enhanced upon nutrient deprivation, including nitrogen, sulfur, or iron starvation, which is considered an effective condition to promote triacylglycerol (TAG) accumulation in microalgae.	Nitrogen	140-148	uncharacterized protein	Chlamydomonas reinhardtii	67-74
23592585-0	2013	How is a metabolic intermediate formed in the mechanism-based inactivation of cytochrome P450 by using 1,1-dimethylhydrazine: hydrogen abstraction or nitrogen oxidation?	Nitrogen	150-158	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	89-93
23414092-5	2013	Pronounced root vs leaf differences in delta15N, however, indicated that nia2 had an increased proportion of nitrogen assimilation of NO3- in leaves while nia1 had an increased proportion of assimilation in roots.	Nitrogen	109-117	nitrate reductase 2	Arabidopsis thaliana	73-77
30428321-2	2018	The synthesized two-dimensional Ni(II)-centered cationic MOF, having its backbone built from purely neutral N-donor ligand, is found to exhibit uncommon resistance over wide pH range, particularly even under highly alkaline conditions.	Nitrogen	32-33	lysine acetyltransferase 8	Homo sapiens	57-60
23956012-0	2013	Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Abeta40.	Nitrogen	12-13	islet amyloid polypeptide	Homo sapiens	33-37
23956012-0	2013	Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Abeta40.	Nitrogen	12-13	islet amyloid polypeptide	Homo sapiens	55-59
23956012-0	2013	Selectively N-methylated soluble IAPP mimics as potent IAPP receptor agonists and nanomolar inhibitors of cytotoxic self-assembly of both IAPP and Abeta40.	Nitrogen	12-13	islet amyloid polypeptide	Homo sapiens	55-59
23757326-3	2013	Thermolysis of 8a (R = nPr) proceeded with hydride transfer from a N-isopropyl substituent to the distal carbon atom of the remaining pentynyl unit at boron to give the zwitterionic five-membered heterocyclic product 10a in good yield.	Nitrogen	67-68	neuronal pentraxin receptor	Homo sapiens	23-26
23649643-1	2013	A series of test compounds were evaluated for an ability to reduce the toxicity of the nitrogen mustard mechlorethamine (HN2) in vitro.	Nitrogen	87-95	MT-RNR2 like 2 (pseudogene)	Homo sapiens	121-124
23522834-2	2013	By optimizing both the N-8 substituent and the biaryl region of the inhibitors we obtained single digit nanomolar compounds such as 37 with excellent selectivity for Plk-2 over Plk-1.	Nitrogen	23-24	polo-like kinase 2	Rattus norvegicus	166-171
29717862-0	2018	MOF-Templated N-Doped Carbon-Coated CoSe2 Nanorods Supported on Porous CNT Microspheres with Excellent Sodium-Ion Storage and Electrocatalytic Properties.	Nitrogen	14-15	lysine acetyltransferase 8	Homo sapiens	0-3
23298862-6	2013	Methadone enantiomer and racemate N-demethylation by recombinant-expressed CYP2B6.6 and CYP2B6.1 was determined.	Nitrogen	34-35	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	75-81
23298862-6	2013	Methadone enantiomer and racemate N-demethylation by recombinant-expressed CYP2B6.6 and CYP2B6.1 was determined.	Nitrogen	34-35	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	88-94
23298862-13	2013	Diminished methadone N-demethylation by CYP2B6.6 may provide a mechanistic explanation for clinical observations of altered methadone disposition in individuals carrying the CYP2B6*6 polymorphism.	Nitrogen	21-22	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	40-46
23907880-4	2013	Ag3 is four-coordinated by two O atoms from two L2 anions and two AgI cations in a slightly distorted square geometry, while Ag4 is also four-coordinated by two O atoms from one L1 and one L2 ligand, one N atom from another L2 anion, and one AgI cation, exhibiting a distorted tetrahedral coordination geometry.	Nitrogen	204-205	anterior gradient 3, protein disulphide isomerase family member	Homo sapiens	0-3
29846664-5	2018	Those results show that the relation between macroscopic electrical resistivity of a-CNx film and its nitrogen content is because of the decrease of sp2: C-C bonding and the formation of sp2: C-N and sp3: C-C and C-N bonding conformation induced by an introduction of nitrogen atoms.	Nitrogen	268-276	calnexin	Homo sapiens	85-88
24137346-4	2013	In the lung tissues from the RT+NS group, the malondialdehyde (MDA) levels were significantly elevated and superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) activities were significantly reduced; the total cell counts and inflammatory cell proportions in the bronchoalveolar lavage fluid (BALF), plasma tumor necrosis factor (TNF)-alpha and transforming growth factor (TGF)-beta1 concentrations and the hydroxyproline (HP) content were significantly increased.	Nitrogen	32-34	transforming growth factor, beta 1	Mus musculus	354-392
29795979-11	2018	Results: RAP improved the renal function indices, including 24-h albuminuria, triglyceride, serum creatinine, and blood urea nitrogen levels, but did not lower blood glucose levels in DN mice.	Nitrogen	125-133	low density lipoprotein receptor-related protein associated protein 1	Mus musculus	9-12
23810534-4	2013	This downregulation is suppressed by inactivation of the TORC1 pathway regulatory Iml1 complex, which also regulates TORC1 during nitrogen starvation.	Nitrogen	130-138	GTPase-activating protein IML1	Saccharomyces cerevisiae S288C	82-86
23506873-5	2013	UT-B isoforms are also important in several cellular functions, including urea nitrogen salvaging in the colon, nitric oxide pathway modulation in the hippocampus, and the normal cardiac conduction system.	Nitrogen	79-87	solute carrier family 14 (urea transporter), member 1	Mus musculus	0-4
23416491-0	2013	Glucosyltransferase UGT76C1 finely modulates cytokinin responses via cytokinin N-glucosylation in Arabidopsis thaliana.	Nitrogen	79-80	UDP-glucosyl transferase 76C1	Arabidopsis thaliana	20-27
29549048-0	2018	The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition.	Nitrogen	28-29	nicotinamide N-methyltransferase	Homo sapiens	65-97
23416491-2	2013	The glucosyltransferase UGT76C1 capable of N-glucosylation of different cytokinins at the N(7)- and N(9)-position was previously identified in Arabidopsis thaliana, but its physiological relevance in plants remains unclear.	Nitrogen	43-44	UDP-glucosyl transferase 76C1	Arabidopsis thaliana	24-31
23416491-10	2013	Taken together, our data suggest that the glucosyltransferase UGT76C1 could finely modulate cytokinin responses in planta via N-glucosylation of cytokinins.	Nitrogen	126-127	UDP-glucosyl transferase 76C1	Arabidopsis thaliana	62-69
23553289-3	2013	However, the (3+2) cycloaddition reaction barriers can be dramatically lowered by coordination of a Lewis acid to the N atom of the -SNO group.	Nitrogen	118-119	strawberry notch homolog 1	Homo sapiens	133-136
29701035-0	2018	[Expression, purification and characterization of N-glycosylation mutant human IFN-lambda1 in Pichia pastoris].	Nitrogen	50-51	interferon lambda 1	Homo sapiens	79-90
23774830-6	2013	The enzyme kinetic studies showed that the initial metabolic step in humans, the N-deethylation, was catalyzed by CYP2B6 and CYP3A4.	Nitrogen	81-82	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	114-120
23307947-2	2013	hMRAPa enhances hMC2R N-linked glycosylation and maturation, promotes hMC2R cell surface expression and enables ACTH to bind and activate the MC2R.	Nitrogen	22-23	melanocortin 2 receptor	Homo sapiens	16-21
23307947-2	2013	hMRAPa enhances hMC2R N-linked glycosylation and maturation, promotes hMC2R cell surface expression and enables ACTH to bind and activate the MC2R.	Nitrogen	22-23	melanocortin 2 receptor	Homo sapiens	17-21
29394472-2	2018	The reaction of the trigonal trisimidazolium salts H3 L(PF6 )3 , decorated with three N-olefinic pendants, and silver oxide yielded trinuclear trisilver(I) hexacarbene molecular cylinders of the type [Ag3 L2 ]3+ with the olefinic pendants from the two different tricarbene ligands arranged in three pairs.	Nitrogen	86-87	sperm associated antigen 17	Homo sapiens	56-59
23097182-4	2013	When the COD/N ratio was lowered from 13 to 3, we found up to 244% higher ammonia removal rate but at least 19% lower ammonia removal efficiency.	Nitrogen	13-14	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	9-12
23995409-9	2013	Highly significant effects due to liquid nitrogen exposure were observed in leaves: increased levels of peroxidase enzymatic and specific activities and cell wall-linked phenolics.	Nitrogen	41-49	peroxidase	Solanum lycopersicum	104-114
22975359-2	2013	The aim of this study was to further investigate the effects of NS-398 on the changes in expression and/or activity of COX-2, cytochrome P450 4A1 (CYP4A1), inducible NO synthase (iNOS), and peroxynitrite formation in serum, renal, cardiac, and/or vascular tissues of lipopolysaccharide (LPS)-treated rats.	Nitrogen	64-66	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	119-124
23200892-9	2013	TUNEL (p&lt;0,001) and caspase-3 (p&lt;0,001) positive cells increased in n-6 group whereas all degenerative observations decreased in n-6+ALA group.	Nitrogen	20-21	caspase 3	Rattus norvegicus	23-32
22961935-3	2013	Herein, we prepared RGDS peptide photocaged either on the Arg-Gly backbone amide nitrogen atom (R[-]GDS) or Asp side chain carboxyl (RG[D]S).	Nitrogen	81-89	ral guanine nucleotide dissociation stimulator	Homo sapiens	20-24
23624514-0	2013	Meigo governs dendrite targeting specificity by modulating ephrin level and N-glycosylation.	Nitrogen	76-77	medial glomeruli	Drosophila melanogaster	0-5
23624514-6	2013	Meigo positively regulated the level of Ephrin N-glycosylation, which was required for its optimal function in vivo.	Nitrogen	47-48	medial glomeruli	Drosophila melanogaster	0-5
23624514-7	2013	Thus, Meigo, an ER-resident protein, governs neuronal targeting specificity by regulating ER folding capacity and protein N-glycosylation.	Nitrogen	122-123	medial glomeruli	Drosophila melanogaster	6-11
29670058-6	2018	TGA also revealed decreased thermal stability of C-PIM relative to PIM-CONH2 under both N2 and air atmosphere.	Nitrogen	88-90	T-box transcription factor 1	Homo sapiens	0-3
23583850-1	2013	A novel class of N-substituted glycosmicine derivatives was synthesized, and their anticonvulsant, antioxidant activity and interaction with bovine serum albumin (BSA) were evaluated.	Nitrogen	17-18	albumin	Mus musculus	148-161
23269669-0	2013	Site-specific N-linked glycosylation of receptor guanylyl cyclase C regulates ligand binding, ligand-mediated activation and interaction with vesicular integral membrane protein 36, VIP36.	Nitrogen	14-15	guanylate cyclase 2C	Homo sapiens	49-67
29324269-5	2018	Besides, according to the analysis of N2 adsorption-desorption isotherms, the BET surface area of these aerogel microspheres was in the range of 800-960 m2/g, and a considerable volume of micropores was detected along with the abundant mesospores in these microspheres, which was further confirmed by the TEM image and SAXS curve.	Nitrogen	38-40	delta/notch like EGF repeat containing	Homo sapiens	78-81
23384254-2	2013	In this study, all 25 potential N-linked glycosylation sites (PNGS) on the HIV-1 CRF07_BC Env, FE, were mutated individually to study the effect of their removal on viral infectivity, virion production, and antibody-mediated neutralization.	Nitrogen	32-33	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	90-93
23691084-7	2013	Unexpectedly, we detected a chromosome segregation defect in ribo-1(RNAi) embryos suggesting an essential role of at least one N-glycosylated protein in metaphase-anaphase transition.	Nitrogen	69-70	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	Caenorhabditis elegans	61-67
29545574-5	2018	Here, we investigated the effects of N-glycosylation on protein production and provide evidence that N-glycosylation greatly increases the expression levels of ER-targeted recombinant proteins.	Nitrogen	37-38	epiregulin	Homo sapiens	160-162
24218836-4	2013	Nitrogen adsorption analyses showed that the BET specific surface area and total pore volume increased with iron impregnation.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	45-48
23184930-10	2013	This in turn is more consistent with the existence of distinct pathways for TorC1- and nitrogen limitation-dependent control than it is with these stimuli representing sequential steps in a single regulatory pathway.	Nitrogen	87-95	CREB regulated transcription coactivator 1	Homo sapiens	76-81
29545574-5	2018	Here, we investigated the effects of N-glycosylation on protein production and provide evidence that N-glycosylation greatly increases the expression levels of ER-targeted recombinant proteins.	Nitrogen	101-102	epiregulin	Homo sapiens	160-162
23076795-7	2013	The stimulatory effects of AA persisted in preexisting myotubes via a COX-2-dependent (NS-389-sensitive) pathway, specifically implying dependency on downstream PG biosynthesis.	Nitrogen	87-89	prostaglandin-endoperoxide synthase 2	Mus musculus	70-75
23462048-10	2013	Endo H-mediated deglycosylation of GluR2 resulted in a significantly smaller pool of GluR2 protein to shift in schizophrenia, reflecting less N-linked high mannose and/or hybrid sugars on the GluR2 protein in this illness.	Nitrogen	142-143	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	35-40
29662487-1	2018	Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjogren"s syndrome (pSS) patients.	Nitrogen	53-54	immunoglobulin heavy variable 3-69-1 (pseudogene)	Homo sapiens	134-170
23462048-10	2013	Endo H-mediated deglycosylation of GluR2 resulted in a significantly smaller pool of GluR2 protein to shift in schizophrenia, reflecting less N-linked high mannose and/or hybrid sugars on the GluR2 protein in this illness.	Nitrogen	142-143	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	85-90
23462048-10	2013	Endo H-mediated deglycosylation of GluR2 resulted in a significantly smaller pool of GluR2 protein to shift in schizophrenia, reflecting less N-linked high mannose and/or hybrid sugars on the GluR2 protein in this illness.	Nitrogen	142-143	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	85-90
23462048-11	2013	This was confirmed by immunoisolation of GluR2 and probing with Concanavalin A, a mannose specific lectin; in subjects with schizophrenia GluR2 was significantly less reactive to Concanavalin A. Altered N-linked glycosylation of the GluR2 subunit in schizophrenia suggests abnormal trafficking of AMPA receptors from the ER to the synaptic membrane in schizophrenia.	Nitrogen	203-204	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	138-143
23462048-11	2013	This was confirmed by immunoisolation of GluR2 and probing with Concanavalin A, a mannose specific lectin; in subjects with schizophrenia GluR2 was significantly less reactive to Concanavalin A. Altered N-linked glycosylation of the GluR2 subunit in schizophrenia suggests abnormal trafficking of AMPA receptors from the ER to the synaptic membrane in schizophrenia.	Nitrogen	203-204	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	138-143
23298862-13	2013	Diminished methadone N-demethylation by CYP2B6.6 may provide a mechanistic explanation for clinical observations of altered methadone disposition in individuals carrying the CYP2B6*6 polymorphism.	Nitrogen	21-22	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	174-180
23090712-5	2013	UV-B radiation led to the inhibition in the activities of the key enzymes (nitrate reductase, glutamine synthetase, glutamate synthase) in the nitrogen assimilation, the decrease in the contents of nitrate and soluble proteins, as well as the increase in the content of amino acid in soybean seedlings.	Nitrogen	143-151	inducible nitrate reductase [NADH] 1	Glycine max	75-92
23689219-9	2013	The survival rate of the MMP-2 T:N ratio &gt; 2.5 group was 57.45%, which was significantly reduced compared with that of the T:N ratio &lt;= 2.5 group (86.78%).	Nitrogen	33-34	matrix metallopeptidase 2	Homo sapiens	25-30
23689219-9	2013	The survival rate of the MMP-2 T:N ratio &gt; 2.5 group was 57.45%, which was significantly reduced compared with that of the T:N ratio &lt;= 2.5 group (86.78%).	Nitrogen	128-129	matrix metallopeptidase 2	Homo sapiens	25-30
29662487-1	2018	Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjogren"s syndrome (pSS) patients.	Nitrogen	53-54	immunoglobulin heavy variable 3-69-1 (pseudogene)	Homo sapiens	172-176
23424197-2	2013	Here, we find that when expressed heterologously in yeast, human GLUT4 is subject to nitrogen-regulated trafficking in an ubiquitin-dependent manner similar to Gap1.	Nitrogen	85-93	solute carrier family 2 member 4	Homo sapiens	65-70
22951018-9	2013	Amounts of platelet-derived CD42a(+) particles from patients with sepsis-related renal injury correlated negatively with actual blood urea nitrogen and creatinine concentrations.	Nitrogen	139-147	glycoprotein IX platelet	Homo sapiens	28-33
22974464-9	2013	We propose that the N- and C-terminal phosphorylated regions of UPF1 recruit SMG7 to the functional NMD complex, and then SMG7 transports the PTC-containing transcripts into P bodies for degradation.	Nitrogen	20-21	SMG7 nonsense mediated mRNA decay factor	Homo sapiens	77-81
23359632-3	2013	In the present work, a nitrogen-rich rth-type metal-organic framework (MOF) was constructed based on rational design and careful synthesis.	Nitrogen	23-31	lysine acetyltransferase 8	Homo sapiens	46-75
23359632-4	2013	The MOF presents exceptionally high uptake capacity not only for CO(2) but also for H(2), which is attributed to favorable interactions between the gas molecules and the nitrogen-rich triazole units of the MOF proved by both experimental measurements and theoretical molecular simulations.	Nitrogen	170-178	lysine acetyltransferase 8	Homo sapiens	4-7
23359632-4	2013	The MOF presents exceptionally high uptake capacity not only for CO(2) but also for H(2), which is attributed to favorable interactions between the gas molecules and the nitrogen-rich triazole units of the MOF proved by both experimental measurements and theoretical molecular simulations.	Nitrogen	170-178	lysine acetyltransferase 8	Homo sapiens	206-209
23756390-12	2013	Taken together, COX-2 N-glycosylation inhibition by GS-HCl led to indomethacin sparing effects, based on which combination of GS-HCl and reduced dose of NSAID can provide the strategy to secure stomach from NSAID-induced gastric damage as well as excellent anti-arthritic effects.	Nitrogen	22-23	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	16-21
29662487-1	2018	Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjogren"s syndrome (pSS) patients.	Nitrogen	84-85	immunoglobulin heavy variable 3-69-1 (pseudogene)	Homo sapiens	134-170
23227926-7	2012	However, after MSCs were supplemented with Link N in chondrogenic differentiation medium, the quantity of GAG secreted into the culture medium, as well as aggrecan, COL2A1, and SOX9 gene expression, increased significantly.	Nitrogen	48-49	SRY-box transcription factor 9	Homo sapiens	177-181
29662487-1	2018	Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjogren"s syndrome (pSS) patients.	Nitrogen	84-85	immunoglobulin heavy variable 3-69-1 (pseudogene)	Homo sapiens	172-176
23361846-7	2013	CYP2B6 inhibition reduces methadone N-demethylation and clearance, and alters methadone concentrations, demonstrating an important role for CYP2B6 in clinical methadone disposition.	Nitrogen	36-37	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-6
29292850-0	2018	Turning the Nitrogen Atoms of an Ar2 P-CH2 -N-N-CH2 -PAr2 Motif into Uniquely Configured Stereocenters: A Novel Diphosphane Design for Asymmetric Catalysis.	Nitrogen	12-20	F2R like trypsin receptor 1	Homo sapiens	53-57
23265881-4	2013	Modulation of activity at both receptors through substitution at the pyridone nitrogen led to the identification of potent dual AT1 antagonists/PPARgamma partial agonists.	Nitrogen	78-86	angiotensin II receptor type 1	Homo sapiens	128-131
22750401-1	2012	The enzyme glutamine synthetase (GS; glutamate-ammonia ligase, EC 6.3.1.2) plays an important role in the nitrogen metabolism of fish.	Nitrogen	106-114	glutamate-ammonia ligase (glutamine synthase) b	Danio rerio	11-31
29444815-0	2018	Molecular mechanisms of missense mutations that generate ectopic N-glycosylation sites in coagulation factor VIII.	Nitrogen	65-66	coagulation factor VIII	Homo sapiens	102-113
22935640-0	2012	Influence of the nitrogen content on the optical properties of CNx films.	Nitrogen	17-25	calnexin	Homo sapiens	63-66
22997240-1	2013	Alg3 of Saccharomyces cerevisiae catalyzes the mannosyl transfer from Man-P-Dol to Man(5)GlcNAc(2)-PP-Dol resulting in the formation of Man(6)GlcNAc(2)-PP-Dol, which is then further processed to the final precursor oligosaccharide Glc(3)Man(9)GlcNAc(2) for N-glycosylation of proteins.	Nitrogen	92-93	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	0-4
29444815-12	2018	Our results reveal differential impacts of ectopic N-glycosylation on FVIII folding, trafficking and activity, which highlight complex disease-causing mechanisms of FVIII missense mutations.	Nitrogen	51-52	coagulation factor VIII	Homo sapiens	70-75
29444815-12	2018	Our results reveal differential impacts of ectopic N-glycosylation on FVIII folding, trafficking and activity, which highlight complex disease-causing mechanisms of FVIII missense mutations.	Nitrogen	51-52	coagulation factor VIII	Homo sapiens	165-170
23165940-1	2013	Core2 beta-1,6-N-acetylglucosaminyltransferase (C2GnT) forms an N-acetylglucosamine branch in the O-glycans (core2 O-glycans) of cell surface glycoproteins.	Nitrogen	15-16	glucosaminyl (N-acetyl) transferase 1	Homo sapiens	48-53
22911153-11	2012	Evidence is provided for N-glycosylation of Acvr2b-1-ECD.	Nitrogen	25-26	activin receptor IIB	Mus musculus	44-50
28929175-3	2018	As a part of the oligosaccharyltransferase complex, TUSC3 localizes to the endoplasmic reticulum and functions in final steps of N-glycosylation of proteins, while its loss evokes the unfolded protein response.	Nitrogen	129-130	tumor suppressor candidate 3	Homo sapiens	52-57
22962279-4	2012	Nitrogen adsorption/desorption measurements showed that Fe(3)O(4) nanobelts manifested a BET surface area of 25.04 m(2) g(-1).	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	89-92
22789031-0	2013	Arabidopsis thaliana ASN2 encoding asparagine synthetase is involved in the control of nitrogen assimilation and export during vegetative growth.	Nitrogen	87-95	asparagine synthetase 2	Arabidopsis thaliana	21-25
29282283-4	2018	To that end, the effects of various gene deletions or chemical blocking agents were tested by investigating the expression of PGK1, one of the glycolytic genes most affected after nitrogen replenishment.	Nitrogen	180-188	phosphoglycerate kinase	Saccharomyces cerevisiae S288C	126-130
23700164-10	2013	Besides, topology mapping of 12 transmembrane-helixes was done to predict N- and O-glycosylation sites and to show the highly glycosylated GLUT4 that includes both N- and O-glycosylation sites.	Nitrogen	164-165	solute carrier family 2 member 4	Homo sapiens	139-144
22767315-5	2012	Remarkably, cadmium treatment further increased expression of not only the N-glycosylated COX-2 protein of 72 kDa but also the unglycosylated COX-2 of 66 kDa, as assessed by the unglycosylated COX-2 induced by tunicamycin or glucosamine, known inhibitors of COX-2 N-glycosylation.	Nitrogen	75-76	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	90-95
22767315-10	2012	These results demonstrate that cadmium specifically induces expression of COX-2 through both transcriptional and co-translational (N-glycosylation) regulation in C6 cells in which the cadmium-induced COX-2 transcriptional upregulation is closely related to oxidative stress-dependent activation of the family of MAPKs and the cadmium-induced expression of both N-glycosylated and unglycosylated COX-2 proteins is proteasome- and translation-dependent.	Nitrogen	131-132	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	74-79
22767315-10	2012	These results demonstrate that cadmium specifically induces expression of COX-2 through both transcriptional and co-translational (N-glycosylation) regulation in C6 cells in which the cadmium-induced COX-2 transcriptional upregulation is closely related to oxidative stress-dependent activation of the family of MAPKs and the cadmium-induced expression of both N-glycosylated and unglycosylated COX-2 proteins is proteasome- and translation-dependent.	Nitrogen	131-132	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	200-205
22767315-10	2012	These results demonstrate that cadmium specifically induces expression of COX-2 through both transcriptional and co-translational (N-glycosylation) regulation in C6 cells in which the cadmium-induced COX-2 transcriptional upregulation is closely related to oxidative stress-dependent activation of the family of MAPKs and the cadmium-induced expression of both N-glycosylated and unglycosylated COX-2 proteins is proteasome- and translation-dependent.	Nitrogen	131-132	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	200-205
23089909-9	2012	The T/N ratio of LI-cadherin mRNA showed significant association with distant metastasis (p=0.031) and lymphatic invasion especially in advanced gastric cancer (p=0.023).	Nitrogen	6-7	cadherin 17	Homo sapiens	17-28
22761399-10	2012	Finally, the studies on KRAS-regulated N-glycoproteins revealed structural alterations in the core N-glycans of SEMA4B in KRAS-activated human bronchial epithelial cells and functional role of N-glycosylation of TIMP-1 in the regulation of lung adenocarcinoma A549 cell invasion.	Nitrogen	39-40	semaphorin 4B	Homo sapiens	112-118
23370193-5	2013	We also developed a series of HMT inhibitors based on the structure of adenosylmethionine (AdoMet), a cofactor in the methylation reaction, by introducing various alkylamino groups onto the nitrogen atom in place of the sulfur atom of AdoMet.	Nitrogen	190-198	PR/SET domain 9	Homo sapiens	30-33
23555822-6	2013	The results indicated that the N-desethylation of BYZX and M2 was mediated by CYP3A4 and CYP2C8.	Nitrogen	31-32	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	89-95
29266417-2	2018	For the first time, a Cu-based MOF, i.e., Cu-NPMOF is used, whose linkers contain nitrogen and phosphorus heteroatoms, as a single precursor and template to prepare novel Cu3 P nanoparticles (NPs) coated by a N,P-codoped carbon shell that is extended to a hierarchical porous carbon matrix with identical uniform N and P doping (termed Cu3 P@NPPC) as an electrocatalyst.	Nitrogen	82-90	lysine acetyltransferase 8	Homo sapiens	31-34
22863891-2	2012	Nitrogen-containing carbon materials were obtained by direct pyrolysis of the PNA-LS composites at the pyrolytic temperatures ranging from 300 C to 1200 C. The as-prepared PNA-LS composites and their carbon materials were investigated by TGA, SEM, TEM, FTIR and UV-vis spectra, XRD and elemental analysis.	Nitrogen	0-8	T-box transcription factor 1	Homo sapiens	238-241
22885037-0	2012	Multidimensional liquid chromatography platform for profiling alterations of clusterin N-glycosylation in the plasma of patients with renal cell carcinoma.	Nitrogen	87-88	clusterin	Homo sapiens	77-86
22864388-0	2012	Low temperature rate constants for the N + CN   N2 + C reaction: two-dimensional quantum capture calculations on an accurate potential energy surface.	Nitrogen	39-40	calponin 2	Homo sapiens	43-50
29266417-2	2018	For the first time, a Cu-based MOF, i.e., Cu-NPMOF is used, whose linkers contain nitrogen and phosphorus heteroatoms, as a single precursor and template to prepare novel Cu3 P nanoparticles (NPs) coated by a N,P-codoped carbon shell that is extended to a hierarchical porous carbon matrix with identical uniform N and P doping (termed Cu3 P@NPPC) as an electrocatalyst.	Nitrogen	45-46	lysine acetyltransferase 8	Homo sapiens	31-34
29248742-1	2018	The ability of a number of nitrogen-containing compounds that simultaneously carry the adamantane and monoterpene moieties to inhibit Tdp1, an important enzyme of the DNA repair system, is studied.	Nitrogen	27-35	tyrosyl-DNA phosphodiesterase 1	Homo sapiens	134-138
22865502-2	2012	In particular, N(2)-adsorption analysis shows that the BET surface area increases notably from 645.3 to 1209.9 m(2)  g(-1) for SWNTs and SWNT-Zn, respectively.	Nitrogen	15-19	delta/notch like EGF repeat containing	Homo sapiens	55-58
23105135-4	2012	Additionally, when challenged with mycobacterial agonists, macrophages from TLR1 602S/S individuals resist induction of host arginase-1, an enzyme that depletes cellular arginine stores required for the production of antimicrobial reactive nitrogen intermediates.	Nitrogen	240-248	arginase 1	Homo sapiens	125-135
23215512-0	2012	Identification of the nitrogen split interstitial (N-N)(N) in GaN.	Nitrogen	22-30	gigaxonin	Homo sapiens	62-65
23215512-1	2012	Combining electron paramagnetic resonance, density functional theory, and positron annihilation spectroscopy (PAS), we identify the nitrogen interstitial defect in GaN.	Nitrogen	132-140	gigaxonin	Homo sapiens	164-167
22898081-2	2012	In cell cultures, ABCA2 over-expression has been linked with resistance to the anticancer agent, estramustine phosphate (EMP; a nor-nitrogen mustard conjugate of estradiol).	Nitrogen	132-140	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	18-23
29434741-11	2018	Compared with that in the HRTx+NS group, serum levels and graft tissue mRNA expression of IFN-gamma and IL-2 were decreased in the HRTx+CXCL10 Abs group, while TGF-beta mRNA was significantly increased but the serum concentration was not significantly affected.	Nitrogen	31-33	C-X-C motif chemokine ligand 10	Rattus norvegicus	136-142
22842622-6	2012	The molecular mechanism through which gp120 binds host lectins, such as altered N-linked glycosylation profiling, provides further mechanisms influencing HIV-1 capture and transfer.	Nitrogen	80-81	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	38-43
23102099-0	2012	N-myristoylation of the Rpt2 subunit regulates intracellular localization of the yeast 26S proteasome.	Nitrogen	0-1	proteasome regulatory particle base subunit RPT2	Saccharomyces cerevisiae S288C	24-28
29380571-6	2018	Further deletion of MIG1 gene in the SNF1 deletion strain resulted in the de-repression of more genes under nitrogen catabolite repression and up-regulation of genes involved in carbon central metabolism.	Nitrogen	108-116	transcription factor MIG1	Saccharomyces cerevisiae S288C	20-24
22842044-4	2012	CD14(+)CD16(-) monocytes showed a higher production of reactive oxygen and nitrogen intermediates after stimulation with tumor cells, and more pronounced inhibition of tumor growth in vivo.	Nitrogen	75-83	CD14 molecule	Homo sapiens	0-4
22750213-0	2012	N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase.	Nitrogen	0-1	proline rich membrane anchor 1	Mus musculus	56-61
22750213-4	2012	PRiMA is a glycoprotein containing two putative N-linked glycosylation sites.	Nitrogen	48-49	proline rich membrane anchor 1	Mus musculus	0-5
22750213-5	2012	By using site-directed mutagenesis, the asparagine-43 was identified to be the N-linked glycosylation site of PRiMA.	Nitrogen	79-80	proline rich membrane anchor 1	Mus musculus	110-115
22776361-5	2012	Thus, because the ASP3 present in the S288c laboratory strain of S. cerevisiae is induced in response to nitrogen starvation, its acquisition may have aided yeast adaptation to artificial environments.	Nitrogen	105-113	asparaginase ASP3-1	Saccharomyces cerevisiae S288C	18-22
29380571-9	2018	Mig1 and Snf1 might be involved in the hierarchical regulatory network of genes under nitrogen catabolite repression.	Nitrogen	86-94	transcription factor MIG1	Saccharomyces cerevisiae S288C	0-4
29281247-1	2018	We report the effort in designing layered SnS2 nanocrystals decorated on nitrogen and sulfur dual-doped graphene aerogels (SnS2@N,S-GA) as anode material of SIBs.	Nitrogen	73-81	sodium voltage-gated channel alpha subunit 11	Homo sapiens	42-46
22939867-3	2012	Meanwhile, more convincing results are observed in the fat-1 transgenic mice, which are exogenously inserted in a fat-1 gene from Caenorhabditis elegans, which can endogenously convert n-6 polyunsaturated fatty acids (n-6 PUFAs) to n-3 PUFAs.	Nitrogen	3-4	FAT atypical cadherin 1	Homo sapiens	55-60
22608290-2	2012	With the MBR and NF (molecular weight cut off (MWCO): 210 Da), the concentration of total nitrogen (TN) and total phosphorus (TP) was effectively reduced by nitrification by MBR and negatively charged surface of NF (TN: 8.67 mgN/L and TP: 0.46 mgP/L).	Nitrogen	90-98	matrix Gla protein	Homo sapiens	244-247
22820920-2	2012	Recent progress in symbiosis has revealed several key components of host plants required for nitrogen-fixing nodule organogenesis, in which complicated metabolic and signaling pathways in the host plant are reprogrammed to generate nodules in the cortex upon perception of the rhizobial Nod factor.	Nitrogen	93-101	atrophin 1	Homo sapiens	287-290
22669842-5	2012	Pkhd1 is protected from increased blood pressure as well as elevated plasma creatinine and blood urea nitrogen levels.	Nitrogen	102-110	PKHD1 ciliary IPT domain containing fibrocystin/polyductin	Rattus norvegicus	0-5
22544757-3	2012	Here we report the discovery of a novel cycle of acetylation/deacetylation of nuclear YAP induced in response to S(N)2 alkylating agents.	Nitrogen	113-118	Yes1 associated transcriptional regulator	Homo sapiens	86-89
29281247-2	2018	The optimized mass loading of SnS2 along with the addition of nitrogen and sulfur on the surface of GAs results in enhanced electrochemical performance of SnS2@N,S-GA composite.	Nitrogen	62-70	sodium voltage-gated channel alpha subunit 11	Homo sapiens	30-34
22544757-7	2012	Intriguingly, we found that YAP acetylation is induced specifically by S(N)2 alkylating agents and not by other DNA-damaging stimuli.	Nitrogen	71-76	Yes1 associated transcriptional regulator	Homo sapiens	28-31
29281247-2	2018	The optimized mass loading of SnS2 along with the addition of nitrogen and sulfur on the surface of GAs results in enhanced electrochemical performance of SnS2@N,S-GA composite.	Nitrogen	62-70	sodium voltage-gated channel alpha subunit 11	Homo sapiens	155-159
22687393-3	2012	Starting from an observation of an abnormal LZT immunoreactive band in prion-infected mice, subsequent cell biological analyses uncovered a surprisingly coordinated biology of ZIP10 (an LZT member) and prion proteins that involves alterations to N-glycosylation and endoproteolysis in response to manipulations to the extracellular divalent cation milieu.	Nitrogen	246-247	solute carrier family 39 (zinc transporter), member 10	Mus musculus	176-181
22687393-6	2012	The transition metal starvation-induced cleavage of ZIP10 can be differentiated by an immature N-glycosylation signature from a constitutive cleavage targeting the same site.	Nitrogen	95-96	solute carrier family 39 (zinc transporter), member 10	Mus musculus	52-57
29281247-2	2018	The optimized mass loading of SnS2 along with the addition of nitrogen and sulfur on the surface of GAs results in enhanced electrochemical performance of SnS2@N,S-GA composite.	Nitrogen	160-161	sodium voltage-gated channel alpha subunit 11	Homo sapiens	30-34
29281247-2	2018	The optimized mass loading of SnS2 along with the addition of nitrogen and sulfur on the surface of GAs results in enhanced electrochemical performance of SnS2@N,S-GA composite.	Nitrogen	160-161	sodium voltage-gated channel alpha subunit 11	Homo sapiens	155-159
22447725-9	2012	Knockdown of endogenous DNER in hippocampal and N-glycosylation mutations abolished the anti-Tr staining, indicating that glycosylation of DNER is required for it to be recognized by anti-Tr antibodies.	Nitrogen	25-26	delta/notch like EGF repeat containing	Homo sapiens	139-143
29313689-3	2018	Moreover, the cage could give permanent pores that had a BET surface area of 347 m2/g and could adsorb 7.8 wt % CO2 with high CO2/N2 selectivity up to 32 (273 K, 1 bar).	Nitrogen	130-132	delta/notch like EGF repeat containing	Homo sapiens	57-60
22278599-4	2012	RESULTS: Serum cystatin C was correlated with blood urea nitrogen (r = 0.537, p &lt; 0.001), serum creatinine (r = 0.480, p &lt; 0.001) and smoking (r = 0.284, p = 0.021).	Nitrogen	57-65	cystatin C	Homo sapiens	15-25
22778273-10	2012	Moreover, we found that N-linked glycosylation of IL13Ralpha2 contributes in part to the interaction of the antibody to IL13Ralpha2.	Nitrogen	24-25	interleukin 13 receptor subunit alpha 2	Homo sapiens	50-61
22778273-10	2012	Moreover, we found that N-linked glycosylation of IL13Ralpha2 contributes in part to the interaction of the antibody to IL13Ralpha2.	Nitrogen	24-25	interleukin 13 receptor subunit alpha 2	Homo sapiens	120-131
29788888-6	2018	In this review, we will summarize recent progress in our understanding of the underlying molecular mechanisms regulating SCAP/SREBPs and lipid metabolism in malignancies, discuss new findings about SREBP trafficking, which requires SCAP N-glycosylation, and introduce a newly identified microRNA-29-mediated negative feedback regulation of the SCAP/SREBP pathway.	Nitrogen	237-238	SREBF chaperone	Homo sapiens	232-236
22777178-1	2012	Improving the solubility of polysubstituted 1,4-naphthoquinone derivatives was achieved by introducing nitrogen in two different positions of the naphthoquinone core, at C-5 and at C-8 of menadione through a two-step, straightforward synthesis based on the regioselective hetero-Diels-Alder reaction.	Nitrogen	103-111	homeobox C8	Homo sapiens	181-184
22733825-4	2012	In the present study, we have prepared a hex-2;hex-3 double mutant, which possesses a radically altered N-glycomic profile.	Nitrogen	104-105	Beta-N-acetylhexosaminidase	Caenorhabditis elegans	47-52
22803330-5	2012	It has been found that in the crystal structure Asp271 interacts with the pyridine nitrogen atom of PLP through H-bonding in both native and substrate-bound DDC.	Nitrogen	83-91	pyridoxal phosphatase	Homo sapiens	100-103
29788888-6	2018	In this review, we will summarize recent progress in our understanding of the underlying molecular mechanisms regulating SCAP/SREBPs and lipid metabolism in malignancies, discuss new findings about SREBP trafficking, which requires SCAP N-glycosylation, and introduce a newly identified microRNA-29-mediated negative feedback regulation of the SCAP/SREBP pathway.	Nitrogen	237-238	SREBF chaperone	Homo sapiens	232-236
29121535-9	2018	These results, together with the increased antiproliferative capacity of the N-methylated complex Cu-L1Me over that of Cu-L1 are rationalized mainly based on its higher lipophilicity.	Nitrogen	77-78	cullin 1	Homo sapiens	98-103
22695481-0	2012	An MBoC favorite: Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation.	Nitrogen	147-148	malectin	Homo sapiens	18-26
22431362-5	2012	The compounds with a five-atom linker containing a heteroatom (O or S) were found to be the most potent inhibitors of HO-2; 1-(N-benzylamino)-3-(1H-imidazol-1-yl)propane dihydrochloride, with a nitrogen atom in the linker, was found to be inactive.	Nitrogen	194-202	heme oxygenase 2	Homo sapiens	118-122
22441658-7	2012	(3) The expression of CD44v6, ICAM-1, MMP-2 and VEGF of tissue in CO(2) and N(2) group after 1, 2 and 4 weeks of pneumoperitoneum were lower than air group, TIMP-2 and ENS were higher than air group.	Nitrogen	76-80	matrix metallopeptidase 2	Rattus norvegicus	38-43
29378341-9	2018	In IFM+N+I samples from mice, the amount of MFN2, but not that of Cx43 increased.	Nitrogen	7-8	mitofusin 2	Mus musculus	44-48
22710690-2	2012	Upon Hg(2+) binding, the absorption band of MS1 is blue-shifted by 29 nm due to the inhibition of the intramolecular charge transfer from the nitrogen to the BODIPY, resulting in a color change from blue to purple.	Nitrogen	142-150	MS	Homo sapiens	44-47
22669327-2	2012	The aluminum halide salts AlCl(3) and AlBr(3) were reacted with the doubly deprotonated form of the ligand to afford five-coordinate [ONHO(cat)]AlX(solv) complexes (1a, X = Cl, solv = OEt(2); 1b, X = Br, solv = THF), each having a trigonal bipyramidal coordination geometry at the aluminum and containing the [ONHO(cat)](2-) ligand with a protonated, sp(3)-hybridized nitrogen donor.	Nitrogen	368-376	hematopoietic SH2 domain containing	Homo sapiens	144-147
22549002-3	2012	The induction of the heme oxygenase-1/biliverdin reductase-A (HO-1/BVR-A) system in the brain represents one of the earliest mechanisms activated by cells to counteract the noxious effects of increased reactive oxygen species and reactive nitrogen species.	Nitrogen	239-247	biliverdin reductase A	Homo sapiens	67-72
22401767-4	2012	The BmIBP2 also has a signal peptide of 23 amino acids and a potential N-glycosylation site.	Nitrogen	71-72	insulin-related peptide binding protein	Bombyx mori	4-10
22246941-2	2012	Hedgehog APRIL contains two cysteine residues (Cys(196) and Cys(211)), a furin protease cleavage site and a conserved putative N-glycosylation site (Asn(124)).	Nitrogen	127-128	tumor necrosis factor ligand superfamily member 13-like	Erinaceus europaeus	9-14
29525963-3	2018	The DNA fragments obtained from the immunoprecipitation of bZIP1-DNA complexes were analyzed by next-generation sequencing (ChIP-seq), which helped uncover genome-wide associations between a bZIP1 and its targets in plant cells upon fluctuations in nitrogen availability.	Nitrogen	249-257	basic leucine-zipper 1	Arabidopsis thaliana	59-64
23004905-4	2012	Here we present a complementary scheme that is based on the nudged-elastic-band method ordinarily used to find saddle points and we apply the scheme to find the most stable isomers of the phosphorus P(4), P(8) molecules and the corresponding molecules of As(n), Sb(n), and Bi(n) (n = 4,8) in the framework of the density functional theory.	Nitrogen	13-14	S100 calcium binding protein A8	Homo sapiens	205-209
22378617-0	2012	Li2 trapped inside tubiform [n] boron nitride clusters (n=4-8): structures and first hyperpolarizability.	Nitrogen	28-31	ATP binding cassette subfamily A member 12	Homo sapiens	0-3
22178856-8	2012	Statistical analyses indicated that gender, housing type, the ryanodine receptor 1 (RYR1) gene, and batch influenced nitrogen excretion (P &lt; 0.05), but the degree and direction of influences differed between growth stages.	Nitrogen	117-125	ryanodine receptor 1	Sus scrofa	62-82
22178856-8	2012	Statistical analyses indicated that gender, housing type, the ryanodine receptor 1 (RYR1) gene, and batch influenced nitrogen excretion (P &lt; 0.05), but the degree and direction of influences differed between growth stages.	Nitrogen	117-125	ryanodine receptor 1	Sus scrofa	84-88
22178856-11	2012	In comparison to other genotypes, pigs carrying genotype NN (homozygous normal) at the RYR1 locus had the least nitrogen excretion (P &lt; 0.05) at all stages of growth except from 60 to 90 kg.	Nitrogen	112-120	ryanodine receptor 1	Sus scrofa	87-91
29525963-3	2018	The DNA fragments obtained from the immunoprecipitation of bZIP1-DNA complexes were analyzed by next-generation sequencing (ChIP-seq), which helped uncover genome-wide associations between a bZIP1 and its targets in plant cells upon fluctuations in nitrogen availability.	Nitrogen	249-257	basic leucine-zipper 1	Arabidopsis thaliana	191-196
22429123-3	2012	We have used site-saturation mutagenesis at position V117 in the class D beta-lactamase OXA-1 to investigate how alterations in the environment around N-carboxylated K70 affect the ability of that modified residue to carry out its normal function.	Nitrogen	151-152	beta-lactamase OXA-1 precursor	Escherichia coli	88-93
28723346-2	2017	N2 sorption isotherm results shows that the prepared Pd-Zn@CS/SiO2 (1/1) porous membrane had a BET surface area of 26.50m2/g.	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	95-98
22527961-3	2012	Macrocycles with a basic nitrogen in the linker form a salt bridge with Asp86 in CDK2 and Asp698 in FLT3.	Nitrogen	25-33	cyclin dependent kinase 2	Homo sapiens	81-85
22493431-0	2012	N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons.	Nitrogen	0-1	transient receptor potential cation channel subfamily M member 8	Homo sapiens	19-24
22493431-3	2012	Here, we studied the role of the N-glycosylation occurring at the pore loop of TRPM8 on the function of the channel.	Nitrogen	33-34	transient receptor potential cation channel subfamily M member 8	Homo sapiens	79-84
22493431-8	2012	These experiments showed that the lack of N-glycosylation affects the function of native TRPM8 ion channels in a similar way to heterologously expressed ones, causing an important shift of the temperature threshold of cold-sensitive thermoreceptor neurons.	Nitrogen	42-43	transient receptor potential cation channel subfamily M member 8	Homo sapiens	89-94
29226084-0	2017	N-glycosylation and expression in human tissues of the orphan GPR61 receptor.	Nitrogen	0-1	G protein-coupled receptor 61	Homo sapiens	62-67
22654736-10	2012	The segregation of BCATm to astrocytes and BCKDC to neurons provides further support for the existence of a BCAA-dependent glial-neuronal nitrogen shuttle since the data show that BCKAs produced by glial BCATm must be exported to neurons.	Nitrogen	138-146	AT-rich interaction domain 4B	Rattus norvegicus	108-112
22473784-5	2012	In turn, an n-3 deficient diet and fructose interventions disrupted insulin receptor signalling in hippocampus as evidenced by a decrease in phosphorylation of the insulin receptor and its downstream effector Akt.	Nitrogen	1-2	insulin receptor	Rattus norvegicus	68-84
22371475-7	2012	In these neurons, ORL1 desensitization by a supramaximal concentration of N/OFQ was not followed by a decrease in HVA I(Ca) current density or proportion of whole-cell HVA I(Ca) contributed by N-type VGCC as determined using the N-type channel selective blocker, omega-conotoxin CVID.	Nitrogen	74-75	opioid related nociceptin receptor 1	Rattus norvegicus	18-22
22442073-5	2012	N-glycosylation of the two glycosylation sites, Asn393 and Asn366, has differential effects on ASIC1a biogenesis.	Nitrogen	0-1	acid-sensing (proton-gated) ion channel 1	Mus musculus	95-101
22442073-11	2012	These data tie N-glycosylation of ASIC1a with its trafficking.	Nitrogen	15-16	acid-sensing (proton-gated) ion channel 1	Mus musculus	34-40
22473784-5	2012	In turn, an n-3 deficient diet and fructose interventions disrupted insulin receptor signalling in hippocampus as evidenced by a decrease in phosphorylation of the insulin receptor and its downstream effector Akt.	Nitrogen	1-2	insulin receptor	Rattus norvegicus	164-180
29226084-3	2017	In this study, we investigated the post-translational modification of GPR61 by N-glycosylation at an identified consensus N-glycosylation site (N12) and the impact of this modification upon the subcellular expression of the protein.	Nitrogen	79-80	G protein-coupled receptor 61	Homo sapiens	70-75
29226084-3	2017	In this study, we investigated the post-translational modification of GPR61 by N-glycosylation at an identified consensus N-glycosylation site (N12) and the impact of this modification upon the subcellular expression of the protein.	Nitrogen	122-123	G protein-coupled receptor 61	Homo sapiens	70-75
29226084-4	2017	The N-glycosylation inhibitor tunicamycin reduced the apparent molecular weight of immunoreactivity associated with myc-tagged GPR61 by 1-2 kDa, which was comparable to the evident molecular weight of the myc-tagged N12S GPR61 mutant with disrupted consensus N-glycosylation site.	Nitrogen	4-5	G protein-coupled receptor 61	Homo sapiens	127-132
22247544-10	2012	These data uncovered unexpected roles for key amino acids within the highly conserved hydrophobic N- and C-terminal microdomains of IC3 in the coordination of CRH-R1 signaling activity.	Nitrogen	98-99	corticotropin releasing hormone receptor 1	Homo sapiens	159-165
29226084-4	2017	The N-glycosylation inhibitor tunicamycin reduced the apparent molecular weight of immunoreactivity associated with myc-tagged GPR61 by 1-2 kDa, which was comparable to the evident molecular weight of the myc-tagged N12S GPR61 mutant with disrupted consensus N-glycosylation site.	Nitrogen	4-5	G protein-coupled receptor 61	Homo sapiens	221-226
21890503-8	2012	In general, a functional association was found between the glycosaminoglycan and N-glycosylated chains attached to the central core proteins of syndecan-4 and glypican-1 affecting their regulation of muscle cell proliferation, differentiation, and FGF2 responsiveness.	Nitrogen	81-82	syndecan 4	Homo sapiens	144-154
22331429-10	2012	Moreover, less distant organ injury was observed in anti-TGF-beta treated mice as shown by reduced blood urea nitrogen (BUN) and aspartate transaminase (AST) values.	Nitrogen	110-118	transforming growth factor, beta 1	Mus musculus	57-65
22573926-5	2012	The opossum stanniocalcin 1 amino acid sequence had 83% homology with human stanniocalcin 1, and has a conserved putative N-linked glycosylation site.	Nitrogen	122-123	stanniocalcin 1	Homo sapiens	12-27
29226084-4	2017	The N-glycosylation inhibitor tunicamycin reduced the apparent molecular weight of immunoreactivity associated with myc-tagged GPR61 by 1-2 kDa, which was comparable to the evident molecular weight of the myc-tagged N12S GPR61 mutant with disrupted consensus N-glycosylation site.	Nitrogen	216-217	G protein-coupled receptor 61	Homo sapiens	127-132
29226084-6	2017	These results demonstrate that GPR61 is subject to N-glycosylation but suggest this is not a prerequisite for cell surface expression, although N-glycosylation of other proteins may be important for cell membrane expression of GPR61.	Nitrogen	51-52	G protein-coupled receptor 61	Homo sapiens	31-36
21975040-5	2012	To facilitate the electrochemical communication between the CNT layer and GDH, CNT was treated with nitrogen plasma.	Nitrogen	100-108	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	Homo sapiens	74-77
22341070-1	2012	INTRODUCTION: Matrix extracellular phosphoglycoprotein (MEPE), a new member of the small integrin binding ligand N-glycosylated (SIBLING) family, is believed to play multifunctional roles in regulation of cell signaling, mineral homeostasis, and mineralization.	Nitrogen	1-2	matrix extracellular phosphoglycoprotein	Homo sapiens	14-54
28860277-3	2017	Using genetically modified human cells that are deficient in DC2 or KCP2 proteins, we show that loss of DC2 causes a defect in co-translational N-glycosylation of proteins that mimics an STT3A-/- phenotype.	Nitrogen	144-145	oligosaccharyltransferase complex non-catalytic subunit	Homo sapiens	104-107
22341070-1	2012	INTRODUCTION: Matrix extracellular phosphoglycoprotein (MEPE), a new member of the small integrin binding ligand N-glycosylated (SIBLING) family, is believed to play multifunctional roles in regulation of cell signaling, mineral homeostasis, and mineralization.	Nitrogen	1-2	matrix extracellular phosphoglycoprotein	Homo sapiens	56-60
22137605-2	2012	AtNRT2.1 expression plays a key role in the regulation of AtAMT1.1 expression and in the NH(4)(+) ion influx, differentiating the nitrogen source, and particularly, the lack of it.	Nitrogen	130-138	ammonium transporter 1;1	Arabidopsis thaliana	58-66
22137605-3	2012	Nitrogen starvation produces a compensatory effect by AtAMT1.1 when there is an absence of the AtNRT2.1 gene.	Nitrogen	0-8	ammonium transporter 1;1	Arabidopsis thaliana	54-62
22137605-4	2012	Our results also show that, in the atnrt2 mutant lacking both AtNRT2.1 and AtNRT2.2, gene functions present different kinetic parameters on the NH(4)(+) ion influx mediated by the HATS, according to the source and availability of nitrogen.	Nitrogen	230-238	nitrate transporter 2.2	Arabidopsis thaliana	75-83
22137605-5	2012	Finally, the absence of AMT1.1 also produces changes in the kinetic parameters of the NO(3)(-) influx, showing different V(max) values depending on the source of nitrogen available.	Nitrogen	162-170	ammonium transporter 1;1	Arabidopsis thaliana	24-30
22405069-0	2012	Klf15 orchestrates circadian nitrogen homeostasis.	Nitrogen	29-37	Kruppel like factor 15	Homo sapiens	0-5
22405069-3	2012	Here, we provide evidence that a clock-dependent peripheral oscillator, Kruppel-like factor 15 transcriptionally coordinates rhythmic expression of multiple enzymes involved in mammalian nitrogen homeostasis.	Nitrogen	187-195	Kruppel-like factor 15	Mus musculus	72-94
22405069-7	2012	Thus, in mammals, nitrogen homeostasis exhibits circadian rhythmicity, and is orchestrated by Kruppel-like factor 15.	Nitrogen	18-26	Kruppel-like factor 15	Mus musculus	94-116
28990751-0	2017	MOF-Derived ZnO Nanoparticles Covered by N-Doped Carbon Layers and Hybridized on Carbon Nanotubes for Lithium-Ion Battery Anodes.	Nitrogen	16-17	lysine acetyltransferase 8	Homo sapiens	0-3
22371559-6	2012	Although synthetically polyubiquitinated N-htt competed with other Ub conjugates for access to the proteasome, the vast majority of mutant N-htt in cells was not Ub conjugated.	Nitrogen	41-42	huntingtin	Homo sapiens	43-46
22226554-4	2012	Nitrogen adsorption-desorption analysis gives an average pore size of 287.5 A, a BET surface area of 29.33 m2/g and a porosity of 41.8%, respectively.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	81-84
28912343-3	2017	Conversely, in the presence of VIL as the sole nitrogen source, BAT1 expression is hindered while that of BAT2 is activated, resulting in Bat2-dependent VIL catabolism.	Nitrogen	47-55	branched-chain-amino-acid transaminase BAT2	Saccharomyces cerevisiae S288C	138-142
22206960-9	2012	The L-N group showed elevated global MMP activity (284%+-71%) and decreased MMP-8 (37%+-17%) and TIMP-4 (48%+-14) activity.	Nitrogen	6-7	TIMP metallopeptidase inhibitor 4	Homo sapiens	97-103
21952826-0	2012	Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner.	Nitrogen	77-78	transient receptor potential cation channel subfamily V member 5	Oryctolagus cuniculus	37-42
21952826-13	2012	The inhibition of TRPV5 occurs in an N-glycosylation-dependent manner, signifying a common final pathway by which distinct extracellular factors regulate channel activity.	Nitrogen	37-38	transient receptor potential cation channel subfamily V member 5	Oryctolagus cuniculus	18-23
28544332-5	2017	FGF2 treatment greatly alleviated I/R-induced acute renal dysfunction and largely blunted I/R-induced elevation in serum creatinine and blood urea nitrogen, and also the number of TUNEL-positive tubular cells in the kidney.	Nitrogen	147-155	fibroblast growth factor 2	Rattus norvegicus	0-4
22230891-3	2012	We previously reported that N-sulfated heparan sulfates (N-sulfated HS) present in specialized extracellular matrix structures (fractones) and vascular basement membranes bind the neurogenic factor FGF-2 (fibroblast growth factor-2) next to stem cells in the anterior SVZ of the lateral ventricle, the most neurogenic zone in adulthood.	Nitrogen	28-29	fibroblast growth factor 2	Mus musculus	198-203
22121503-2	2012	Here we designed a nitrogen-rich trefoil hexacarboxylate (trigonal tri-isophthalate) ligand, which serves to act as the trigonal molecular building block while concurrently coding the formation of the targeted truncated cuboctahedral supermolecular building block (in situ), and enhancing the CO(2) uptake in the resultant rht-MOF.	Nitrogen	19-27	lysine acetyltransferase 8	Homo sapiens	327-330
22230891-3	2012	We previously reported that N-sulfated heparan sulfates (N-sulfated HS) present in specialized extracellular matrix structures (fractones) and vascular basement membranes bind the neurogenic factor FGF-2 (fibroblast growth factor-2) next to stem cells in the anterior SVZ of the lateral ventricle, the most neurogenic zone in adulthood.	Nitrogen	28-29	fibroblast growth factor 2	Mus musculus	205-231
28811146-8	2017	At a low influent COD/NH4+-N ratio (2.7), the N2O conversion rate was greater when there were more biodegradable carbon substrates.	Nitrogen	22-23	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	18-21
22230891-3	2012	We previously reported that N-sulfated heparan sulfates (N-sulfated HS) present in specialized extracellular matrix structures (fractones) and vascular basement membranes bind the neurogenic factor FGF-2 (fibroblast growth factor-2) next to stem cells in the anterior SVZ of the lateral ventricle, the most neurogenic zone in adulthood.	Nitrogen	57-58	fibroblast growth factor 2	Mus musculus	198-203
22230891-3	2012	We previously reported that N-sulfated heparan sulfates (N-sulfated HS) present in specialized extracellular matrix structures (fractones) and vascular basement membranes bind the neurogenic factor FGF-2 (fibroblast growth factor-2) next to stem cells in the anterior SVZ of the lateral ventricle, the most neurogenic zone in adulthood.	Nitrogen	57-58	fibroblast growth factor 2	Mus musculus	205-231
22227571-2	2012	In this study, we show that surface expression of MICA/B and other NKG2D ligands is dependent on N-linked glycosylation.	Nitrogen	67-68	MHC class I polypeptide-related sequence A	Homo sapiens	50-54
22227571-3	2012	The inhibitor of glycolysis and N-linked glycosylation, 2-deoxy-D-glucose (2DG), potently inhibited surface expression of MICA/B after histone deacetylase inhibitor treatment; the inhibition occurred posttranscriptionally without affecting MICA promoter activity.	Nitrogen	32-33	MHC class I polypeptide-related sequence A	Homo sapiens	122-126
22227571-3	2012	The inhibitor of glycolysis and N-linked glycosylation, 2-deoxy-D-glucose (2DG), potently inhibited surface expression of MICA/B after histone deacetylase inhibitor treatment; the inhibition occurred posttranscriptionally without affecting MICA promoter activity.	Nitrogen	32-33	MHC class I polypeptide-related sequence A	Homo sapiens	240-244
21899873-9	2012	From these data, we propose that His225 enhances radical stability by acting as a hydrogen bond acceptor to the phenolic oxygen, which favors the deprotonated state of the imino nitrogen and leads to greater resonance stabilization of the 2,4-diaminobutyryl-PLP radical intermediate.	Nitrogen	178-186	pyridoxal phosphatase	Homo sapiens	258-261
22287069-5	2012	Unmodified DNA and RNA do not yield such a peak, but they produce electrocatalytic voltammetric signals after modification with osmium tetroxide complexes with nitrogen ligands [Os(VIII)L], binding covalently to pyrimidine bases in nucleic acids.	Nitrogen	160-168	cytochrome c oxidase subunit 8A	Homo sapiens	181-187
22624316-9	2012	Nitrogen fertilization increased NAG activity in the early stages of decay.	Nitrogen	0-8	alpha-N-acetylglucosaminidase family / NAGLU family	Arabidopsis thaliana	33-36
22221176-3	2012	XPS results showed that in chlorine treated FA PA membranes the ratio of bound chlorine to surface nitrogen was 1:1 whereas it was only 1:6 in the case of PIP PA membranes.	Nitrogen	99-107	fibroblast activation protein alpha	Homo sapiens	44-49
29089530-3	2017	The N-doped microporous CSs have a remarkably high N-doping content, over 10%, and high BET surface area of 884.9 m2 g-1.	Nitrogen	4-5	delta/notch like EGF repeat containing	Homo sapiens	88-91
22170731-6	2012	Furthermore, we found that two different crystalline polymorphs of the cage compound 3 a (with tert-butyl substituents) differ also in nitrogen sorption, resulting in a BET surface area of 1377 m(2) g(-1), when synthesized from THF and 2071 m(2) g(-1), when recrystallized from DMSO.	Nitrogen	135-143	delta/notch like EGF repeat containing	Homo sapiens	169-172
20938793-7	2012	The results showed a moderate enhancement of OPG gene expression whereas RANKL gene expression was strongly increased by nitrogen-containing bisphosphonates reaching a maximum after 14 days at high concentrations of 5 x 10(-5) M. Lower concentrations did not enhance the RANKL and OPG expression considerably.	Nitrogen	121-129	TNF receptor superfamily member 11b	Homo sapiens	281-284
20938793-8	2012	The non-nitrogen-containing bisphosphonate clodronate, however, effected OPG and RANKL gene expression much less, even at higher concentrations of 5 x 10(-3) M. The above-mentioned data suggest an enhanced RANKL/OPG gene expression after stimulation by bisphosphonates.	Nitrogen	8-16	TNF receptor superfamily member 11b	Homo sapiens	73-76
20938793-8	2012	The non-nitrogen-containing bisphosphonate clodronate, however, effected OPG and RANKL gene expression much less, even at higher concentrations of 5 x 10(-3) M. The above-mentioned data suggest an enhanced RANKL/OPG gene expression after stimulation by bisphosphonates.	Nitrogen	8-16	TNF receptor superfamily member 11b	Homo sapiens	212-215
29018865-4	2017	By using 77 K nitrogen adsorption isotherm and strictly applying three consistency criteria, the BET surface area for PCN-111 was calculated to be 4825 m2 g-1.	Nitrogen	14-22	delta/notch like EGF repeat containing	Homo sapiens	97-100
22412906-0	2012	Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization.	Nitrogen	63-64	glucagon like peptide 1 receptor	Homo sapiens	22-35
22412906-10	2012	Functional expression of a GIP receptor mutant lacking N-glycosylation is rescued by co-expressed wild type GLP1 receptor, which, together with data obtained using Bioluminescence Resonance Energy Transfer, suggests formation of a GIP-GLP1 receptor heteromer.	Nitrogen	55-56	glucagon like peptide 1 receptor	Homo sapiens	108-121
21448924-10	2012	The inhibition of both the hexosamine pathway and N-linked glycosylation along with Wnt signaling pathway by sFRP1 and DKK1 is associated with significant decrease of the protein levels of GSK3beta, beta-catenin, and TXNIP RNA.	Nitrogen	50-51	secreted frizzled related protein 1	Homo sapiens	109-114
28353172-6	2017	The BET surface area of HMS was evaluated by nitrogen adsorption/desorption analysis.	Nitrogen	45-53	delta/notch like EGF repeat containing	Homo sapiens	4-7
21448924-10	2012	The inhibition of both the hexosamine pathway and N-linked glycosylation along with Wnt signaling pathway by sFRP1 and DKK1 is associated with significant decrease of the protein levels of GSK3beta, beta-catenin, and TXNIP RNA.	Nitrogen	50-51	dickkopf WNT signaling pathway inhibitor 1	Homo sapiens	119-123
21448924-10	2012	The inhibition of both the hexosamine pathway and N-linked glycosylation along with Wnt signaling pathway by sFRP1 and DKK1 is associated with significant decrease of the protein levels of GSK3beta, beta-catenin, and TXNIP RNA.	Nitrogen	50-51	glycogen synthase kinase 3 beta	Homo sapiens	189-197
22036730-3	2012	Site directed mutagenesis of the N-linked glycosylation sites in NSP4 was employed to show that glycosylation of NSP4 was not required for it to promote changes in the MT network.	Nitrogen	33-34	serine protease 57	Homo sapiens	65-69
29082358-7	2017	The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls.	Nitrogen	170-171	Mir17 host gene (non-protein coding)	Mus musculus	4-12
22649382-4	2011	The ability of JAK2 to promote cell surface localization and stability of TpoR required the first N-glycosylation site (Asn117).	Nitrogen	98-99	Janus kinase 2	Homo sapiens	15-19
22015362-2	2011	Static electric fields in air at a nominal pressure of 625 Torr and temperature of 300 K are detected using vibrational CARS of nitrogen.	Nitrogen	128-136	cysteinyl-tRNA synthetase 1	Homo sapiens	120-124
20641269-18	2004	Nitrogen-containing synthetic diphosphonates are inhibitors of farnesyl diphosphate synthase (FDPS) of osteoclast and are used for treatment of osteoporosis (bone resorption) (9).	Nitrogen	0-8	farnesyl diphosphate synthase	Rattus norvegicus	63-92
20641269-18	2004	Nitrogen-containing synthetic diphosphonates are inhibitors of farnesyl diphosphate synthase (FDPS) of osteoclast and are used for treatment of osteoporosis (bone resorption) (9).	Nitrogen	0-8	farnesyl diphosphate synthase	Rattus norvegicus	94-98
22822294-1	2012	Nitrogen adsorption/desorption isotherms are used to investigate the Brunauer, Emmett, and Teller (BET) surface area and Barrett-Joyner-Halenda (BJH) pore size distribution of physically modified, thermally annealed, and octadecanethiol functionalized np-Au monoliths.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	99-102
22844534-11	2012	A segment of the loop maintains packing interactions with the helical structure by an extended non-polar surface of the alphaX CT. Interactions between alphaX and beta2 CTs are demonstrated by (15)N-(1)H HSQC NMR experiments.	Nitrogen	197-198	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	163-168
22427986-0	2012	Loss and recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions.	Nitrogen	59-60	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	21-26
21114545-11	2011	In this period, increasing the level of DUP in diet increased the content of blood urea nitrogen (p &lt; 0.05).	Nitrogen	88-96	mutS homolog 3	Homo sapiens	40-43
29082358-7	2017	The miR17~92 osteoclast conditional knockout (cKO) mutants, generated by breeding miR17~92loxp/loxp mice with Ctsk-Cre mice, had lower Tb.BV/TV, Tb.BMD, Tb.Conn-Dens, Tb.N, and Tb.Th, but larger Tb.Sp, and greater bone resorption without a change in bone formation compared to littermate controls.	Nitrogen	170-171	Mir17 host gene (non-protein coding)	Mus musculus	4-9
22427986-0	2012	Loss and recovery of Mgat3 and GnT-III Mediated E-cadherin N-glycosylation is a mechanism involved in epithelial-mesenchymal-epithelial transitions.	Nitrogen	59-60	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	31-38
28779986-0	2017	Gas adsorption on commercial magnesium stearate: Effects of degassing conditions on nitrogen BET surface area and isotherm characteristics.	Nitrogen	84-92	delta/notch like EGF repeat containing	Homo sapiens	93-96
22493903-10	2012	(2) The levels of P-p38 protein was markedly ascended in H3d group (0.225 +/- 0.071) compared with N group (0.012 +/- 0.006), and expression of P-p38 protein was significantly positive in H1w, H2w, H4w groups.	Nitrogen	99-100	mitogen activated protein kinase 14	Rattus norvegicus	20-23
22493903-12	2012	(3) As P-p38 protein in pulmonary arterial tunica intima and tunica media, sterile expression in N group (0.099 +/- 0.015) and H3d group (0.107 +/- 0.013) contrasted to H4w group (0.124 +/- 0.025, P &lt; 0.05), then tended to rise in H2w, H4w group (P &lt; 0.05).	Nitrogen	97-98	mitogen activated protein kinase 14	Rattus norvegicus	9-12
21624033-3	2011	Maize Dof1 (ZmDof1) is a plant-specific transcription factor shown to promote nitrogen assimilation in Arabidopsis thaliana (Arabidopsis) even under nitrogen-deficient conditions.	Nitrogen	149-157	DNA-binding protein MNB1	Zea mays	12-18
21624033-4	2011	The present study examines the effect of the introduction of the ZmDof1 gene on carbon and nitrogen assimilation in rice.	Nitrogen	91-99	DNA-binding protein MNB1	Zea mays	65-71
21624033-6	2011	Transgenic rice expressing ZmDof1 and grown in the presence of 360 mum (nitrogen-sufficient) or 90 mum (nitrogen-deficient) of nitrogen concentrations showed modulation of metabolite content and gene expression associated with the anaplerotic pathway for the TCA cycle, suggesting an increased carbon flow towards nitrogen assimilation.	Nitrogen	72-80	DNA-binding protein MNB1	Zea mays	27-33
21624033-6	2011	Transgenic rice expressing ZmDof1 and grown in the presence of 360 mum (nitrogen-sufficient) or 90 mum (nitrogen-deficient) of nitrogen concentrations showed modulation of metabolite content and gene expression associated with the anaplerotic pathway for the TCA cycle, suggesting an increased carbon flow towards nitrogen assimilation.	Nitrogen	104-112	DNA-binding protein MNB1	Zea mays	27-33
21624033-6	2011	Transgenic rice expressing ZmDof1 and grown in the presence of 360 mum (nitrogen-sufficient) or 90 mum (nitrogen-deficient) of nitrogen concentrations showed modulation of metabolite content and gene expression associated with the anaplerotic pathway for the TCA cycle, suggesting an increased carbon flow towards nitrogen assimilation.	Nitrogen	104-112	DNA-binding protein MNB1	Zea mays	27-33
21624033-6	2011	Transgenic rice expressing ZmDof1 and grown in the presence of 360 mum (nitrogen-sufficient) or 90 mum (nitrogen-deficient) of nitrogen concentrations showed modulation of metabolite content and gene expression associated with the anaplerotic pathway for the TCA cycle, suggesting an increased carbon flow towards nitrogen assimilation.	Nitrogen	104-112	DNA-binding protein MNB1	Zea mays	27-33
21624033-7	2011	Furthermore, increases in carbon and nitrogen amounts per seedling were found in Dof1 rice grown under nitrogen-deficient conditions.	Nitrogen	37-45	DNA-binding protein MNB1	Zea mays	81-85
21624033-7	2011	Furthermore, increases in carbon and nitrogen amounts per seedling were found in Dof1 rice grown under nitrogen-deficient conditions.	Nitrogen	103-111	DNA-binding protein MNB1	Zea mays	81-85
22012574-1	2011	The crystal structure of an N(2)-encapusulated MOF, which is stable under open-air conditions at ambient temperature, was determined by single-crystal X-ray diffraction at 123 K. The crystal MOF of [HSm{V(IV)O(TPPS)}](n) designed to have 1-D channels periodically constricted by porphyrins planes adsorbed N(2) at 77 K. The adsorbed N(2) molecules remained in the 1-D channels even after warming to ambient temperature.	Nitrogen	28-32	lysine acetyltransferase 8	Homo sapiens	47-50
28779986-2	2017	Characteristics of nitrogen adsorption/desorption isotherms are assessed through the linearity of low relative pressure isotherm data and the BET transform plot together with the extent of isotherm hysteresis.	Nitrogen	19-27	delta/notch like EGF repeat containing	Homo sapiens	142-145
22012574-1	2011	The crystal structure of an N(2)-encapusulated MOF, which is stable under open-air conditions at ambient temperature, was determined by single-crystal X-ray diffraction at 123 K. The crystal MOF of [HSm{V(IV)O(TPPS)}](n) designed to have 1-D channels periodically constricted by porphyrins planes adsorbed N(2) at 77 K. The adsorbed N(2) molecules remained in the 1-D channels even after warming to ambient temperature.	Nitrogen	28-32	lysine acetyltransferase 8	Homo sapiens	191-194
21624033-9	2011	Measurement of the CO2 gas exchange rate showed a significant increase in the net photosynthesis rate in Dof1 rice under nitrogen-deficient conditions.	Nitrogen	121-129	DNA-binding protein MNB1	Zea mays	105-109
21624033-10	2011	Taken these together, the present study displayed that ZmDof1 expression in rice could induce gene expressions such as PEPC genes, modulate carbon and nitrogen metabolites, increase nitrogen assimilation and enhance growth under low-nitrogen conditions.	Nitrogen	151-159	DNA-binding protein MNB1	Zea mays	55-61
21624033-10	2011	Taken these together, the present study displayed that ZmDof1 expression in rice could induce gene expressions such as PEPC genes, modulate carbon and nitrogen metabolites, increase nitrogen assimilation and enhance growth under low-nitrogen conditions.	Nitrogen	182-190	DNA-binding protein MNB1	Zea mays	55-61
28779986-9	2017	Possible mechanisms for atypical isotherms are critically discussed together with the suitability of applying BET theory to nitrogen adsorption data.	Nitrogen	124-132	delta/notch like EGF repeat containing	Homo sapiens	110-113
21624033-10	2011	Taken these together, the present study displayed that ZmDof1 expression in rice could induce gene expressions such as PEPC genes, modulate carbon and nitrogen metabolites, increase nitrogen assimilation and enhance growth under low-nitrogen conditions.	Nitrogen	182-190	DNA-binding protein MNB1	Zea mays	55-61
22156730-2	2011	[PSI+], [RNQ+] and [URE3] are well characterized prions in Saccharomyces cerevisiae and represent the aggregated states of the translation termination factor Sup35, a functionally unknown protein Rnq1, and a regulator of nitrogen metabolism Ure2, respectively.	Nitrogen	221-229	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	158-163
21880831-5	2011	Blocking CCR2 using the selective CCR2 antagonist RS504393 for 12 wk in Ins2(Akita) mice significantly attenuated albuminuria, the increase in blood urea nitrogen and plasma creatinine, histological changes, and glomerular macrophage recruitment compared with vehicle.	Nitrogen	154-162	chemokine (C-C motif) receptor 2	Mus musculus	9-13
21921116-9	2011	Strikingly, SDH1-1/sdh1-1 seedlings grew considerably better in nitrogen-limiting conditions.	Nitrogen	64-72	succinate dehydrogenase 1-1	Arabidopsis thaliana	12-18
21921116-9	2011	Strikingly, SDH1-1/sdh1-1 seedlings grew considerably better in nitrogen-limiting conditions.	Nitrogen	64-72	succinate dehydrogenase 1-1	Arabidopsis thaliana	19-25
28530234-9	2017	Intracranial self-stimulation in rats showed that elongating the N-alkyl chain decreased abuse-related effects in vivo that appeared to parallel reductions in DAT activity.	Nitrogen	65-66	solute carrier family 6 member 3	Rattus norvegicus	159-162
22046147-0	2011	Molecular Assembly and Biosynthesis of Acetylcholinesterase in Brain and Muscle: the Roles of t-peptide, FHB Domain, and N-linked Glycosylation.	Nitrogen	121-122	acetylcholinesterase (Cartwright blood group)	Gallus gallus	39-59
21880708-4	2011	All N-methylated analogues showed impaired binding affinities to IR, which suggests a direct IR-interacting role for the respective amide hydrogens.	Nitrogen	4-5	insulin receptor	Homo sapiens	65-67
21880708-4	2011	All N-methylated analogues showed impaired binding affinities to IR, which suggests a direct IR-interacting role for the respective amide hydrogens.	Nitrogen	4-5	insulin receptor	Homo sapiens	93-95
21932766-4	2011	Utilizing the dipeptide N(2)S(2-) ligand, H(2)N-Gly-l-Cys-OMe (GC-OMeH(2)), an accurate model of the structural and electronic contributions provided by His1 and Cys2 in Ni-SOD(red), we constructed the dinuclear sulfur-bridged metallosynthon, [Ni(2)(GC-OMe)(2)] (1).	Nitrogen	24-29	viral integration site 1	Homo sapiens	153-157
21803396-4	2011	The effectiveness of the strategy was demonstrated using abattoir wastewater, containing nitrogen and phosphorus at approximately 250 mgN/L and 30 mgP/L, respectively.	Nitrogen	89-97	matrix Gla protein	Homo sapiens	147-150
21910969-6	2011	We prepared mouse PrP mutants with increasing number of consecutive Q/N residues in the B2-H2 loop.	Nitrogen	70-71	prion protein	Mus musculus	18-21
21910969-11	2011	Our results thus suggest that Q/N residues in the B2-H2 loop of PrP promote protein conversion and may represent a link to conversion of Q/N-rich prions.	Nitrogen	32-33	prion protein	Mus musculus	64-67
21910969-11	2011	Our results thus suggest that Q/N residues in the B2-H2 loop of PrP promote protein conversion and may represent a link to conversion of Q/N-rich prions.	Nitrogen	139-140	prion protein	Mus musculus	64-67
21625987-1	2011	The peptide hormone ghrelin is secreted in the stomach, with unique N-octanoylation at serine 3, which is a requirement for its functionality.	Nitrogen	68-69	appetite-regulating hormone	Capra hircus	20-27
21795704-5	2011	The expression of the AChE(T) mutant, in which all N-glycosylation sites were deleted, together with PRiMA in HEK293T cells produced a glycan-depleted PRiMA-linked AChE tetramer but with a much higher K(m) value as compared with the wild type.	Nitrogen	51-52	proline rich membrane anchor 1	Homo sapiens	151-156
21757715-0	2011	N-glycosylation is critical for the stability and intracellular trafficking of glucose transporter GLUT4.	Nitrogen	0-1	solute carrier family 2 member 4	Homo sapiens	99-104
21637915-5	2011	Only the second peptide (emp#2), which contains a putative N-glycosylation site sequence, inhibited emmprin-stimulated production of MMP-2 in co-cultures of fibroblasts and several different human tumor cells types, including carcinoma, sarcoma, melanoma, leukemia and glioma cells.	Nitrogen	59-60	matrix metallopeptidase 2	Homo sapiens	133-138
21949153-8	2011	Removal of the critical N-terminal Ser-rich region or either of the two Tyr-dependent sorting motifs from RTNLB1 causes partial reversion of the negative effects of excess RTNLB1 on FLS2 transport out of the ER and accumulation at the membrane.	Nitrogen	24-25	Leucine-rich receptor-like protein kinase family protein	Arabidopsis thaliana	182-186
21594722-1	2011	PURPOSE: PR-104 is activated by reductases under hypoxia or by aldo-keto reductase 1C3 (AKR1C3) to form cytotoxic nitrogen mustards.	Nitrogen	114-122	aldo-keto reductase family 1 member C3	Homo sapiens	63-86
21594722-1	2011	PURPOSE: PR-104 is activated by reductases under hypoxia or by aldo-keto reductase 1C3 (AKR1C3) to form cytotoxic nitrogen mustards.	Nitrogen	114-122	aldo-keto reductase family 1 member C3	Homo sapiens	88-94
21328067-6	2011	When we analyzed the specific nutritional content of the diet, we found that the percentage of nitrogen in diet was negatively correlated with residual maltase activity and positively correlated with the ratio aminopeptidase-N/maltase.	Nitrogen	95-103	alanyl aminopeptidase, membrane	Homo sapiens	210-226
21694675-0	2011	Methoxymethyl (MOM) group nitrogen protection of pyrimidines bearing C-6 acyclic side-chains.	Nitrogen	26-34	complement C6	Homo sapiens	69-72
21694675-1	2011	Novel N-methoxymethylated (MOM) pyrimidine (4-13) and pyrimidine-2,4-diones (15-17) nucleoside mimetics in which an isobutyl side-chain is attached at the C-6 position of the pyrimidine moiety were synthesized.	Nitrogen	0-1	complement C6	Homo sapiens	155-158
21694675-2	2011	Synthetic methods via O-persilylated or N-anionic uracil derivatives have been evaluated for the synthesis of N-1- and/or N-3-MOM pyrimidine derivatives with C-6 acyclic side-chains.	Nitrogen	40-41	complement C6	Homo sapiens	158-161
21478030-7	2011	The results indicate that the asn2-1 mutant was impaired in nitrogen assimilation and translocation under salt treatment.	Nitrogen	60-68	asparagine synthetase 2	Arabidopsis thaliana	30-34
21521696-1	2011	The Arabidopsis (Arabidopsis thaliana) soluble N-ethylmaleimide-sensitive factor attachment protein receptor SYP41 is involved in vesicle fusion at the trans-Golgi network (TGN) and interacts with AtVPS45, SYP61, and VTI12.	Nitrogen	47-48	Vesicle transport v-SNARE family protein	Arabidopsis thaliana	217-222
21454642-2	2011	Previous biochemical studies revealed that DinB family DNA polymerases, including Escherichia coli DNA polymerase IV and human DNA polymerase kappa, efficiently incorporate the correct nucleotide opposite some N(2)-modified 2"-deoxyguanosine derivatives.	Nitrogen	210-214	DNA polymerase kappa	Homo sapiens	127-147
21572394-5	2011	Loss of NgBR results in a robust deficit in cis-IPTase activity and Dol-P production, leading to diminished levels of dolichol-linked oligosaccharides and a broad reduction in protein N-glycosylation.	Nitrogen	8-9	dehydrodolichyl diphosphate synthase subunit	Homo sapiens	44-54
21431216-3	2011	When two comparable rod-like linkers 4bpy and abp (with different N,N"-donor separations of the molecular backbones of ca.	Nitrogen	66-70	amine oxidase copper containing 1	Homo sapiens	46-49
21827189-0	2011	Role of the pyridine nitrogen in pyridoxal 5"-phosphate catalysis: activity of three classes of PLP enzymes reconstituted with deazapyridoxal 5"-phosphate.	Nitrogen	21-29	pyridoxal phosphatase	Homo sapiens	96-99
21770429-1	2011	Human interleukin-5 receptor alpha (IL5Ralpha) is a glycoprotein that contains four N-glycosylation sites in the extracellular region.	Nitrogen	84-85	interleukin 5 receptor subunit alpha	Homo sapiens	6-34
21770429-1	2011	Human interleukin-5 receptor alpha (IL5Ralpha) is a glycoprotein that contains four N-glycosylation sites in the extracellular region.	Nitrogen	84-85	interleukin 5 receptor subunit alpha	Homo sapiens	36-45
21487941-1	2011	BACKGROUND: Serum concentrations of N-terminal natriuretic pro-brain natriuretic peptide (NT-proBNP) correlate well with the severity of cardiac disease in children and adults.	Nitrogen	8-9	natriuretic peptide B	Homo sapiens	63-88
21652715-0	2011	Npr1 Ser/Thr protein kinase links nitrogen source quality and carbon availability with the yeast nitrate transporter (Ynt1) levels.	Nitrogen	34-42	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	118-122
21652715-1	2011	Ynt1, the single high affinity nitrate and nitrite transporter of the yeast Hansenula polymorpha, is regulated by the quality of nitrogen sources.	Nitrogen	129-137	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	0-4
21652715-2	2011	Preferred nitrogen sources cause Ynt1 dephosphorylation, ubiquitinylation, endocytosis, and vacuolar degradation.	Nitrogen	10-18	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	33-37
21652715-3	2011	In contrast, under nitrogen limitation Ynt1 is phosphorylated and sorted to the plasma membrane.	Nitrogen	19-27	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	39-43
21652715-4	2011	We show here the involvement of the Ser/Thr kinase HpNpr1 in Ynt1 phosphorylation and regulation of Ynt1 levels in response to nitrogen source quality and the availability of carbon.	Nitrogen	127-135	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	61-65
21652715-4	2011	We show here the involvement of the Ser/Thr kinase HpNpr1 in Ynt1 phosphorylation and regulation of Ynt1 levels in response to nitrogen source quality and the availability of carbon.	Nitrogen	127-135	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	100-104
21652715-6	2011	As a result, in this strain Ynt1 is sorted to the vacuole, from both plasma membrane and the later biosynthetic pathway in nitrogen-free conditions and nitrate.	Nitrogen	123-131	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	28-32
21652715-12	2011	We concluded that Npr1 plays a key role in adapting Ynt1 levels to the nitrogen quality and availability of a source of carbon.	Nitrogen	71-79	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	52-56
21577179-5	2011	RESULTS: At 5 hr, serum creatinine and blood urea nitrogen levels were markedly reduced in IFNAR-/- mice as compared with WT.	Nitrogen	50-58	interferon (alpha and beta) receptor 1	Mus musculus	91-96
21666701-8	2011	RESULTS: Incubation of HCC cells under hypoxia (1% O2, 5% CO2, 94% N2) for 36 h significantly increased CA-IX expression level.	Nitrogen	67-69	carbonic anhydrase 9	Homo sapiens	104-109
20919935-5	2011	In PTPs, the initially generated sulfenic acid residues have the potential to undergo secondary reactions with a neighboring amide nitrogen or cysteine thiol residue to yield a sulfenyl amide or disulfide, respectively.	Nitrogen	131-139	6-pyruvoyltetrahydropterin synthase	Homo sapiens	3-7
21586563-6	2011	Using progesterone as substrate for bacterially expressed purified human P450c17, the Michaelis constant for 17alpha-hydroxylase activity supported by N-27 POR or N-27 POR-G3H6 were 1.73 or 1.49 mum, and the maximal velocity was 0.029 or 0.026 pmol steroids per picomole P450 per minute, respectively.	Nitrogen	151-152	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	73-80
21586563-6	2011	Using progesterone as substrate for bacterially expressed purified human P450c17, the Michaelis constant for 17alpha-hydroxylase activity supported by N-27 POR or N-27 POR-G3H6 were 1.73 or 1.49 mum, and the maximal velocity was 0.029 or 0.026 pmol steroids per picomole P450 per minute, respectively.	Nitrogen	163-164	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	73-80
21586563-7	2011	Using 17-hydroxypregnenolone as the P450c17 substrate, the Michaelis constant for 17,20 lyase activity using N-27 POR or N-27 POR-G3H6 was 1.92 or 1.89 mum and the maximal velocity was 0.041 or 0.042 pmol steroid per picomole P450 per minute, respectively.	Nitrogen	109-110	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	36-43
21586563-7	2011	Using 17-hydroxypregnenolone as the P450c17 substrate, the Michaelis constant for 17,20 lyase activity using N-27 POR or N-27 POR-G3H6 was 1.92 or 1.89 mum and the maximal velocity was 0.041 or 0.042 pmol steroid per picomole P450 per minute, respectively.	Nitrogen	121-122	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	36-43
21575138-0	2011	N-Glycosylation influences the structure and self-association abilities of recombinant nucleolin.	Nitrogen	0-1	nucleolin	Homo sapiens	87-96
21575138-3	2011	We have previously found that nucleolin undergoes complex N- and O-glycosylations in extra-nuclear isoforms.	Nitrogen	58-59	nucleolin	Homo sapiens	30-39
21575138-7	2011	Here, owing to the inability to quantitatively produce full-size nucleolin, we expressed four N-glycosylation nucleolin variants lacking the N-terminal acidic domain in a baculovirus/insect cell system.	Nitrogen	94-95	nucleolin	Homo sapiens	110-119
21575138-10	2011	Our results demonstrate that all nucleolin-derived variants are able to self-interact and that N-glycosylation on both RBD1 and RBD3, or RBD3 alone, but not RBD1 alone, modifies the structure of the N-terminally truncated nucleolin and enhances its self-association properties.	Nitrogen	95-96	nucleolin	Homo sapiens	33-42
21575138-10	2011	Our results demonstrate that all nucleolin-derived variants are able to self-interact and that N-glycosylation on both RBD1 and RBD3, or RBD3 alone, but not RBD1 alone, modifies the structure of the N-terminally truncated nucleolin and enhances its self-association properties.	Nitrogen	95-96	nucleolin	Homo sapiens	222-231
21575138-12	2011	Our results suggest that the occupancy of the N-glycosylation sites may contribute to expression and functions of surface nucleolin.	Nitrogen	46-47	nucleolin	Homo sapiens	122-131
21592255-6	2011	The relative expression of N-methyl-d-aspartic acid (NMDA)-NR1 subunit in the lumbo-sacral (L6-S1) spinal cord was examined using Western blot.	Nitrogen	27-28	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	59-62
21327607-9	2011	Although all cysteines are conserved between the two species, macaque CD32 exhibits two additional N-linked glycosylation sites, whereas CD64 lacks three of them when compared to humans.	Nitrogen	99-100	Fc gamma receptor IIa	Homo sapiens	70-74
21569239-7	2011	The unique feature of F-spondin FS domain is the presence of three disulfide bonds associated with the N- and C-termini of the domain and a highly conserved N-linked glycosylation site.	Nitrogen	103-104	spondin 1	Homo sapiens	22-31
21354155-9	2011	Salmon IGFBP-2s are also unique in terms of having potential N-glycosylation sites and splice variants.	Nitrogen	61-62	insulin like growth factor binding protein 2	Homo sapiens	7-14
21405023-7	2011	The increase in the size of the VAP-1 ligands, together with the methylation of the secondary nitrogen atom of the hydrazine moiety, improves the VAP-1 selectivity over MAO.	Nitrogen	94-102	amine oxidase copper containing 3	Homo sapiens	32-37
21405023-7	2011	The increase in the size of the VAP-1 ligands, together with the methylation of the secondary nitrogen atom of the hydrazine moiety, improves the VAP-1 selectivity over MAO.	Nitrogen	94-102	amine oxidase copper containing 3	Homo sapiens	146-151
21239382-4	2011	In Arabidopsis, increasing evidence suggests that, for nitrate, the main nitrogen source for most plant species, a major sensor is the NRT1.1 nitrate transporter, also contributing to nitrate uptake by the roots.	Nitrogen	73-81	nicotinamide riboside transporter	Saccharomyces cerevisiae S288C	135-139
21248204-2	2011	The yeast homologues Sro7 and Sro77 are thought to act downstream of the Rab GTPase Sec4 to promote soluble N-ethylmaleimide-sensitive factor adaptor protein receptor (SNARE) function in post-Golgi transport.	Nitrogen	108-109	Rab family GTPase SEC4	Saccharomyces cerevisiae S288C	84-88
21214274-5	2011	Superimposition of active sites of the four simulated models (wild type and three variants) with the human TCII crystal structure revealed that the distance between the Nepsilon nitrogen atom of His-173 and the cobalt ion of cobalamin deviated considerably in the I5V model as compared to wild type and other variants.	Nitrogen	178-186	transcobalamin 2	Homo sapiens	107-111
21310322-9	2011	After multivariable adjustment, both BTP (hazard ratio: 1.41, 95% confidence interval: 1.06 to 1.88; p = 0.018) and cystatin C (hazard ratio: 1.50, 95% confidence interval: 1.13 to 2.01; p = 0.006) were significant predictors of death/HF hospitalization, whereas serum creatinine, estimated glomerular filtration rate, and blood urea nitrogen were no longer significant.	Nitrogen	334-342	cystatin C	Homo sapiens	116-126
21295282-10	2011	DHDDS is a key enzyme in the pathway of dolichol, which plays an important role in N-glycosylation of many glycoproteins, including rhodopsin.	Nitrogen	83-84	dehydrodolichyl diphosphate synthase subunit	Homo sapiens	0-5
21291557-10	2011	Dsp averages one sialic acid per N-glycosylation, which is always in the form of N-acetylneuraminic acid.	Nitrogen	33-34	dentin sialophosphoprotein	Homo sapiens	0-3
21291557-13	2011	CONCLUSIONS: The distribution of porcine Dsp posttranslational modifications indicate that porcine Dsp has an N-terminal domain with at least six N-glycosylations and a C-terminal domain with two GAG attachments and at least two O-glycosylations.	Nitrogen	2-3	dentin sialophosphoprotein	Homo sapiens	99-102
21093406-2	2011	A search in the human genome for methyltransferases capable of catalyzing the N-methylation of benzylisoquinoline alkaloids, as biosynthetic precursors of morphine, yielded two enzymes, PNMT (EC 2.1.1.28) and NMT (EC 2.1.1.49).	Nitrogen	78-79	phenylethanolamine N-methyltransferase	Homo sapiens	186-190
21184740-7	2011	Results presented herein show that induced expression of catabolic and biosynthetic genes when cells are grown under nitrogen derepressive conditions and amino acid deprivation is dependent on the concurrent action of Gln3 and Gcn4, which form part of a unique transcriptional complex.	Nitrogen	117-125	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	227-231
21307597-0	2011	Ecl1, a regulator of the chronological lifespan of Schizosaccharomyces pombe, is induced upon nitrogen starvation.	Nitrogen	94-102	epistatic circling A C57L/J 1	Mus musculus	0-4
21307597-4	2011	Here we analyzed the expression profile of Ecl1, especially as to cell cycle and growth phase, and found that it is induced upon nitrogen starvation.	Nitrogen	129-137	epistatic circling A C57L/J 1	Mus musculus	43-47
21307597-6	2011	Though the nitrogen starvation-induced expression of Ecl1 did not change in the atf1Delta mutant, induction in both the ste11Delta mutant and the tor1Delta mutant showed a delay.	Nitrogen	11-19	epistatic circling A C57L/J 1	Mus musculus	53-57
21329806-2	2011	UPR transducers IRE1, PERK, ATF6, and UPR-responsive genes such as GRP78/BiP, ERAD genes such as EDEM, and synthesis of the protein N-linked glycosylation donor lipid-linked oligosaccharides (LLOs) are mobilized.	Nitrogen	132-133	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	16-20
22346586-3	2011	The BET surface area (SSA(BET)) of the nanoparticles was measured by nitrogen adsorption.	Nitrogen	69-77	delta/notch like EGF repeat containing	Homo sapiens	4-7
28662963-0	2017	Activity cliff for 7-substituted pyrrolo-pyrimidine inhibitors of HCK explained in terms of predicted basicity of the amine nitrogen.	Nitrogen	124-132	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	66-69
22346586-3	2011	The BET surface area (SSA(BET)) of the nanoparticles was measured by nitrogen adsorption.	Nitrogen	69-77	delta/notch like EGF repeat containing	Homo sapiens	26-29
20204527-7	2010	The synthesis of beta-galactosidase from the PDI2-lacZ fusion gene was markedly enhanced in the Pap1-positive KP1 cells by SNP and nitrogen starvation.	Nitrogen	131-139	galactosidase beta 1	Homo sapiens	17-35
20204527-8	2010	However, the enhancement in the synthesis of beta-galactosidase from the PDI2-lacZ fusion gene by SNP and nitrogen starvation appeared to be relatively reduced in the Pap1-negative TP108-3C cells than in the Pap1-positive KP1 cells.	Nitrogen	106-114	galactosidase beta 1	Homo sapiens	45-63
28662963-4	2017	We assumed that the basicity of the amine nitrogen, which formed an ionic bond with Asp348 of HCK, markedly affected inhibitory activity against HCK.	Nitrogen	42-50	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	94-97
28662963-4	2017	We assumed that the basicity of the amine nitrogen, which formed an ionic bond with Asp348 of HCK, markedly affected inhibitory activity against HCK.	Nitrogen	42-50	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	145-148
28630087-12	2017	The heavily N-glycosylated HNE protease inhibitor, alpha1-antitrypsin, displayed concentration-dependent complex formation and preferred glycoform-glycoform interactions with HNE.	Nitrogen	12-13	elastase, neutrophil expressed	Homo sapiens	175-178
21108709-1	2010	CPS1 is a mitochondrial matrix enzyme that catalyzes the first committed step of the urea cycle, the primary system for removing nitrogen produced by protein metabolism using N-acetylglutamate.	Nitrogen	129-137	carbamoyl-phosphate synthase 1	Homo sapiens	0-4
28678517-7	2017	This study thus provides insights into the interplay among FUT8, GnT-IV, and GnT-V in N-linked glycosylation during the assembly of glycoproteins.	Nitrogen	86-87	fucosyltransferase 8	Homo sapiens	59-63
20923886-8	2010	When investigating the effects of increased S and N phloem transport on seed metabolism, we found that protein levels were improved in MMP1 seeds.	Nitrogen	50-51	S-methylmethionine permease MMP1	Saccharomyces cerevisiae S288C	135-139
28706275-0	2017	Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation.	Nitrogen	0-1	pappalysin 1	Homo sapiens	18-55
20977456-0	2010	Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes.	Nitrogen	42-43	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	17-23
28706275-8	2017	In summary, this study suggests that PAPPA is essential to maintain a receptive endometrium by up-regulating N-fucosylation, which is a potential useful biomarker to evaluate the receptive functions of the endometrium.	Nitrogen	109-110	pappalysin 1	Homo sapiens	37-42
20713656-3	2010	Among the 12 UGT isoforms tested, the O- and N-glucuronidation of 1"-hydroxymidazolam was mediated by UGT2B4/2B7 and 1A4, respectively.	Nitrogen	45-46	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	13-16
28487369-0	2017	N-Glycosylation affects the stability and barrier function of the MUC16 mucin.	Nitrogen	0-1	LOC100508689	Homo sapiens	72-77
21097712-5	2010	Furthermore, the enhanced resistance in lht1 could be attributed to a specific deficiency of its main physiological substrate, Gln, and not to a general nitrogen deficiency.	Nitrogen	153-161	lysine histidine transporter 1	Arabidopsis thaliana	40-44
28662078-2	2017	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine phosphotransferase (GPT), the protein encoded by DPAGT1, is an endoplasmic reticulum (ER)-resident protein involved in an initial step in the N-glycosylation pathway.	Nitrogen	4-5	glutamic--pyruvic transaminase	Homo sapiens	83-86
20702592-5	2010	The TIM2(-/-) mice showed approximately fivefold higher injury as estimated by blood urea nitrogen and serum creatinine at 48 h that was confirmed by significantly increased proximal tubular damage assessed histologically (H &amp; E staining).	Nitrogen	90-98	T cell immunoglobulin and mucin domain containing 2	Mus musculus	4-8
20693288-0	2010	N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.	Nitrogen	0-1	Wnt family member 3A	Homo sapiens	47-50
20693288-9	2010	Furthermore, up-regulation of DPAGT1 transcripts by Wnt3a led to altered N-glycosylation of E-cadherin.	Nitrogen	73-74	Wnt family member 3A	Homo sapiens	52-57
20693288-11	2010	Our results provide the first evidence that the Wnt/beta-catenin signaling pathway regulates the metabolic pathway of protein N-glycosylation by targeting DPAGT1 expression.	Nitrogen	126-127	Wnt family member 3A	Homo sapiens	48-51
20927321-5	2010	Our studies have shown that the n-3 PUFA species, docosahexaenoic acid (DHA), increases SDC-1 expression in prostate tissues of Pten knockout (Pten(P-/-)) mice/cells and human prostate cancer cells.	Nitrogen	21-22	syndecan 1	Mus musculus	88-93
20501912-8	2010	Kinetic analysis of dextromethorphan metabolism indicated that the apparent K(m) and V(max) of CYP2D17 and CYP2D44 catalyzed O-demethylation were similar, and, the V(max) values of CYP2D17 and CYP2D44 catalyzed N-demethylation (which human CYP2D6 catalyzes much less effectively) were similar, but the apparent K(m) of the CYP2D44 reaction was higher.	Nitrogen	211-212	cytochrome P450 family 2 subfamily D member 8	Macaca fascicularis	107-114
28642782-7	2017	Both iron deficiency and nitrogen starvation resulted in down-regulation of AtACP4.	Nitrogen	25-33	acyl carrier protein 4	Arabidopsis thaliana	76-82
20573065-6	2010	SAC1 depletion also induced a unique pattern of Golgi-specific defects in N-and O-linked glycosylation.	Nitrogen	74-75	SAC1 like phosphatidylinositide phosphatase	Homo sapiens	0-4
21443176-2	2011	In 2, the EDA molecule has been inserted into one Co-S bond in 1 with the loss of N(2) to form an 18-electron compound containing a three-membered metallacyclic ring.	Nitrogen	82-86	ectodysplasin A	Homo sapiens	10-13
28263809-4	2017	BET surface area of SSNS was evaluated by nitrogen adsorption/desorption analysis.	Nitrogen	42-50	delta/notch like EGF repeat containing	Homo sapiens	0-3
21292995-1	2011	N-glycosylation of immunoglobulin G (IgG) has an important impact on the modification of the total serum N-glycome in chronic liver patients.	Nitrogen	0-1	immunoglobulin heavy variable V1-62	Mus musculus	37-40
21292995-1	2011	N-glycosylation of immunoglobulin G (IgG) has an important impact on the modification of the total serum N-glycome in chronic liver patients.	Nitrogen	105-106	immunoglobulin heavy variable V1-62	Mus musculus	37-40
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	aquaporin 3	Bos taurus	223-227
21090303-7	2010	When the influent concentration of COD is lower than 350 mg/L, the promotion of C/N ratio which in the range of 10-20 is obvious, and the promotion decreases along with the increase of C/N ratio.	Nitrogen	82-83	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	35-38
21090303-7	2010	When the influent concentration of COD is lower than 350 mg/L, the promotion of C/N ratio which in the range of 10-20 is obvious, and the promotion decreases along with the increase of C/N ratio.	Nitrogen	187-188	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	35-38
28282581-3	2017	Nitrogen-coordinated gold complexes have been used to disaggregate prion neuropeptide (PrP106-126) and human islet amyloid polypeptide (hIAPP).	Nitrogen	0-8	islet amyloid polypeptide	Homo sapiens	136-141
20504761-8	2010	The binding of GS, the principal ammonia assimilatory enzyme, to the conserved C-terminal domain of nod26, a transporter of NH(3), is proposed to promote efficient assimilation of fixed nitrogen, as well as prevent potential ammonia toxicity, by localizing the enzyme to the cytosolic side of the symbiosome membrane.	Nitrogen	186-194	nodulin-26	Glycine max	100-105
21356592-2	2011	The N-mustard pharmacophore was attached at the C-6 of the 4-anilinoquinazolines via a urea linker.	Nitrogen	4-5	complement C6	Homo sapiens	48-51
28538732-5	2017	KL cells express the urea cycle enzyme carbamoyl phosphate synthetase-1 (CPS1), which produces carbamoyl phosphate in the mitochondria from ammonia and bicarbonate, initiating nitrogen disposal.	Nitrogen	176-184	carbamoyl-phosphate synthase 1	Homo sapiens	39-71
21385933-7	2011	Immunohistochemical validation of two well-known cellular tumor pathways (TGF-beta and beta-catenin) confirmed that the TGF-beta pathway (positivity of Smad4) was related to N(0) (OR: 0.20, 95% CI: 0.06-0.66) and the beta-catenin pathway (p120 positivity) to N(+) (OR: 1.79, 95%CI: 1.05-3.05).	Nitrogen	259-263	SMAD family member 4	Homo sapiens	152-157
20405899-4	2010	beta-N-Acetylglucosaminidase (endo-beta-GlcNAc-ases, Endo-M) is an endoglycosidase capable of hydrolyzing N,N"-diacetylchitobiose moiety in N-linked oligosaccharides bound to the asparagine amino acid residue in various glycoproteins.	Nitrogen	106-110	O-GlcNAcase	Homo sapiens	0-28
28538732-5	2017	KL cells express the urea cycle enzyme carbamoyl phosphate synthetase-1 (CPS1), which produces carbamoyl phosphate in the mitochondria from ammonia and bicarbonate, initiating nitrogen disposal.	Nitrogen	176-184	carbamoyl-phosphate synthase 1	Homo sapiens	73-77
21143198-6	2011	Furthermore, both Pho87 and Pho90 are also targeted to the vacuole upon carbon-source starvation or upon treatment with rapamycin, which mimics nitrogen starvation, but although these responses are independent of PHO pathway signalling, they again require the N-terminal SPX domain of the transporters.	Nitrogen	144-152	SPX domain-containing inorganic phosphate transporter	Saccharomyces cerevisiae S288C	18-23
21143198-6	2011	Furthermore, both Pho87 and Pho90 are also targeted to the vacuole upon carbon-source starvation or upon treatment with rapamycin, which mimics nitrogen starvation, but although these responses are independent of PHO pathway signalling, they again require the N-terminal SPX domain of the transporters.	Nitrogen	144-152	SPX domain-containing inorganic phosphate transporter	Saccharomyces cerevisiae S288C	28-33
20627594-2	2010	This provides evidence that covalent inhibitors of POP do not have to be limited to structures containing five-membered N-containing heterocyclic rings.	Nitrogen	120-121	prolyl endopeptidase	Homo sapiens	51-54
28538732-8	2017	Notably, cell death results from pyrimidine depletion rather than ammonia toxicity, as CPS1 enables an unconventional pathway of nitrogen flow from ammonia into pyrimidines.	Nitrogen	129-137	carbamoyl-phosphate synthase 1	Homo sapiens	87-91
28371293-2	2017	The TiO2 /Ni passivated n-GaP/i-GaNP/p+ -GaP thin film heterojunction provides much higher photoanodic performance in 1 m KOH solution than the TiO2 /Ni-coated n-GaP substrate, leading to much lower onset potential and much higher photocurrent.	Nitrogen	24-25	minichromosome maintenance complex component 3 associated protein	Homo sapiens	32-36
20156436-2	2010	Previously, we reported that reduction of E-cadherin N-glycosylation in normal and cancer cells promoted stabilization of AJs through changes in the composition and cytoskeletal association of E-cadherin scaffolds.	Nitrogen	53-54	cadherin 1	Canis lupus familiaris	42-52
20156436-2	2010	Previously, we reported that reduction of E-cadherin N-glycosylation in normal and cancer cells promoted stabilization of AJs through changes in the composition and cytoskeletal association of E-cadherin scaffolds.	Nitrogen	53-54	cadherin 1	Canis lupus familiaris	193-203
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	39-40	cadherin 1	Canis lupus familiaris	159-169
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	63-64	cadherin 1	Canis lupus familiaris	159-169
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	63-64	cadherin 1	Canis lupus familiaris	159-169
20466873-1	2010	The chemical warfare agents sulfur mustard (SM) and nitrogen mustards (HN-1, HN-2, and HN-3) are highly reactive vesicants.	Nitrogen	52-60	Jupiter microtubule associated homolog 1	Mus musculus	71-75
21287576-8	2011	Lipid peroxidation (LP), urea nitrogen and lactate dehydrogenase (LDH) levels were higher in CycA group than in control and ceftriaxone groups although LP, urea nitrogen and LDH levels were lower in ceftriaxone + CycA group than in control and ceftriaxone groups.	Nitrogen	30-38	peptidylprolyl isomerase A	Rattus norvegicus	93-97
20978011-11	2011	Our findings support a new concept that regulation of Man2C1 expression is essential for maintaining efficient protein N-glycosylation.	Nitrogen	119-120	mannosidase alpha class 2C member 1	Homo sapiens	54-60
20844569-5	2011	Expression levels of 82 genes diagnostic for transformations in the marine nitrogen, phosphorus and sulfur cycles ranged from below detection (&lt;1 x 10(6) transcripts per liter) for 36 genes (for example, phosphonate metabolism gene phnH, dissimilatory nitrate reductase subunit napA) to &gt;2.7 x 10(9) transcripts per liter (ammonia transporter amt and ammonia monooxygenase subunit amoC).	Nitrogen	75-83	NSF attachment protein alpha	Homo sapiens	281-285
21219905-5	2011	In contrast, inhibition of N-myristoylation of a calcium-dependent protein kinase was sufficient to alter its localization from the plasma membrane to chloroplasts and chloroplast localization of ferredoxin-NADP+ reductase and Rubisco activase could be efficiently suppressed by artificial introduction of myristoylation and palmitoylation sites.	Nitrogen	27-28	ferredoxin reductase	Homo sapiens	196-222
28613381-1	2017	The relative quantitative real-time expression of two expressed sequence tags (ESTs) codifying for key enzymes in nitrogen metabolism in maize, nitrate reductase (ZmNR), and glutamine synthetase (ZmGln1-3) was performed for genotypes inoculated with Azospirillum brasilense.	Nitrogen	114-122	glutamine synthetase root isozyme 3	Zea mays	196-204
20980142-4	2011	A combination of nitrogen deficiency, moderately high light intensity (82.5 muE m(-2) s(-1)) and high level of iron (0.74 mM) improved lipid accumulation in TRG, KB, SK, and PSU strains up to 35.9%, 30.2%, 28.4% and 14.7%, respectively.	Nitrogen	17-25	T cell receptor gamma locus	Homo sapiens	157-160
20404084-8	2010	Loss of Cha4 or Ago1 causes aberrant induction of per1 under noninducing conditions, suggesting that these proteins are also involved in per1 regulation and hence in nitrogen utilization.	Nitrogen	166-174	Cha4p	Saccharomyces cerevisiae S288C	8-12
20498861-1	2010	A Zn-MOF assembled from a new C(2h)-symmetric terphenyl dicarboxylate and DABCO was prepared and characterized by X-ray crystallography and gas sorption analysis: a preferential sorption of CO(2) over N(2) and H(2) was observed with an exceptionally high CO(2) adsorption enthalpy.	Nitrogen	201-205	lysine acetyltransferase 8	Homo sapiens	5-8
28593196-8	2017	The regulatory proteins PII and PipX were decreased, and the global nitrogen regulator NtcA was upregulated.	Nitrogen	68-76	ntcA	Prochlorococcus marinus subsp. marinus str. CCMP1375	87-91
20470756-2	2010	Previously we isolated thioredoxin from soybean nodules as one of differentially expressed genes during nodulation and noted its positive role in nitrogen fixation.	Nitrogen	146-154	thioredoxin	Glycine max	23-34
20594879-0	2011	Phosphorylation of spinal N-methyl-d-aspartate receptor NR1 subunits by extracellular signal-regulated kinase in dorsal horn neurons and microglia contributes to diabetes-induced painful neuropathy.	Nitrogen	26-27	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	56-59
20470756-6	2010	With an increased uricase activity observed also in the presence of thioredoxin, these results appear to implicate a novel role of thioredoxin in the regulation of enzyme activities involved in nodule development and nitrogen fixation.	Nitrogen	217-225	uricase-2 isozyme 1	Glycine max	18-25
28952523-0	2017	Comparative N-Glycosylation Analysis of the Fc Portions of a Chimeric Human Coagulation Factor VIII and Immunoglobulin G1.	Nitrogen	12-13	coagulation factor VIII	Homo sapiens	76-99
20470756-6	2010	With an increased uricase activity observed also in the presence of thioredoxin, these results appear to implicate a novel role of thioredoxin in the regulation of enzyme activities involved in nodule development and nitrogen fixation.	Nitrogen	217-225	thioredoxin	Glycine max	68-79
20470756-6	2010	With an increased uricase activity observed also in the presence of thioredoxin, these results appear to implicate a novel role of thioredoxin in the regulation of enzyme activities involved in nodule development and nitrogen fixation.	Nitrogen	217-225	thioredoxin	Glycine max	131-142
22272114-0	2011	Structural requirements of N-substituted spiropiperidine analogues as agonists of nociceptin/orphanin FQ receptor.	Nitrogen	27-28	opioid related nociceptin receptor 1	Homo sapiens	93-113
28952523-3	2017	While human-like N-glycosylation of recombinant FVIII is known to be crucial for the clotting factor"s quality and function, the particular glycosylation of the fused Fc portion has not been investigated in detail so far, despite its known impact on Fcgamma receptor binding.	Nitrogen	17-18	coagulation factor VIII	Homo sapiens	48-53
20964536-6	2011	The Katp and Kca agonists cromakalim and NS 1619 produced vasodilation that was impaired after FPI more in males than in females.	Nitrogen	41-43	casein kappa	Homo sapiens	13-16
20481535-3	2010	Nitrogen gas adsorption measurements performed at 77 K revealed a type I isotherm, indicating BET and Langmuir surface areas of 1810 and 2040 m(2)/g, respectively.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	94-97
28952523-4	2017	Here, we analyzed the N-glycosylation of the Fc part of a chimeric FVIII-Fc protein compared to a commercial IgG1 purified from human plasma.	Nitrogen	22-23	coagulation factor VIII	Homo sapiens	67-72
28351617-9	2017	These results demonstrated that FAM5C is an N-glycosylated protein and N-glycosylation is necessary for the secretion of FAM5C.	Nitrogen	71-72	BMP/retinoic acid inducible neural specific 3	Homo sapiens	121-126
20378536-2	2010	TorC1 and intracellular nitrogen levels regulate the localization of Gln3 and Gat1, the activators of nitrogen catabolite repression (NCR)-sensitive genes whose products are required to utilize poor nitrogen sources.	Nitrogen	24-32	Gat1p	Saccharomyces cerevisiae S288C	78-82
20952484-6	2011	Crystallographic analysis of the charge-transfer complex indicated that a Mo-nitrogen-carbon bond was formed between molybdenum of XOR and the nitrile group of trihydroxy-FYX-051.	Nitrogen	77-85	xanthine dehydrogenase	Rattus norvegicus	131-134
20378536-2	2010	TorC1 and intracellular nitrogen levels regulate the localization of Gln3 and Gat1, the activators of nitrogen catabolite repression (NCR)-sensitive genes whose products are required to utilize poor nitrogen sources.	Nitrogen	102-110	Gat1p	Saccharomyces cerevisiae S288C	78-82
20378536-3	2010	In nitrogen excess, Gln3 and Gat1 are cytoplasmic, and NCR-sensitive transcription is repressed.	Nitrogen	3-11	Gat1p	Saccharomyces cerevisiae S288C	29-33
20378536-4	2010	During nitrogen limitation or Rap treatment, Gln3 and Gat1 are nuclear, and transcription is derepressed.	Nitrogen	7-15	Gat1p	Saccharomyces cerevisiae S288C	54-58
21577056-4	2010	Here we show that KIN3 gene deficient cells present sensitivity and fail to arrest properly at G2/M-phase checkpoint in response to the DNA damage inducing agents MMS, cisplatin, doxorubicin and nitrogen mustard, suggesting that Kin3 can be involved in DNA strand breaks recognition or signaling.	Nitrogen	195-203	serine/threonine protein kinase KIN3	Saccharomyces cerevisiae S288C	18-22
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	Gat1p	Saccharomyces cerevisiae S288C	142-146
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	phosphoprotein phosphatase 2A catalytic subunit PPH21	Saccharomyces cerevisiae S288C	197-202
28247191-1	2017	Site-specific characterization of the N- and O-linked glycosylation on a set of different human chorionic gonadotropin (hCG) drug products was performed by a LC-MS method combining high resolution (120K at m/z 200) mass spectrometry, multiple dissociation methods, tandem mass tag (TMT 10plex) labeling, and partial least squares-discriminant analysis (PLS-DA).	Nitrogen	38-39	chorionic gonadotropin subunit beta 5	Homo sapiens	120-123
22046405-0	2011	The interaction between the first transmembrane domain and the thumb of ASIC1a is critical for its N-glycosylation and trafficking.	Nitrogen	99-100	acid-sensing (proton-gated) ion channel 1	Mus musculus	72-78
20207824-2	2010	Focusing on Asn13 and Asn26 positioned on N-linked glycosylation motifs in the amino-terminal domain of human somatostatin receptor subtype-5 (hSSTR5), we performed site-directed mutagenesis and evaluated the mutants by using yeast cells as the host strain.	Nitrogen	42-43	somatostatin receptor 5	Homo sapiens	110-141
20207824-2	2010	Focusing on Asn13 and Asn26 positioned on N-linked glycosylation motifs in the amino-terminal domain of human somatostatin receptor subtype-5 (hSSTR5), we performed site-directed mutagenesis and evaluated the mutants by using yeast cells as the host strain.	Nitrogen	42-43	somatostatin receptor 5	Homo sapiens	143-149
21625387-6	2011	A significant reduction of CDK5R1 mRNA and p35 levels was observed after transfection of SK-N-BE neuroblastoma cells with the miR-103 or miR-107 precursor (pre-miR-103 or pre-miR-107).	Nitrogen	36-37	microRNA 107	Homo sapiens	137-144
28235739-4	2017	The characterisation of HMW-DOM fraction evidenced an ageing of organic compounds going from surface layers to the deepest ones with a shift from aliphatic compounds and proteins/amino sugars to more high unsaturated character and less nitrogen content.	Nitrogen	236-244	cilia and flagella associated protein 97	Homo sapiens	24-27
20627793-1	2011	Synthetic nanosized Zn-Al-hydrotalcite (Zn-Al-HT) with 20 nm crystallite size and 61 m(2)/g BET-surface area is found to be a mild and efficient catalyst for N-sulfonylation of amines in quantitative yields under ultrasound irradiation.	Nitrogen	158-159	delta/notch like EGF repeat containing	Homo sapiens	92-95
20202172-10	2010	Growth of fum2 plants was similar to that of the wild type in low nitrogen but much slower in the presence of high nitrogen.	Nitrogen	66-74	FUMARASE 2	Arabidopsis thaliana	10-14
20202172-10	2010	Growth of fum2 plants was similar to that of the wild type in low nitrogen but much slower in the presence of high nitrogen.	Nitrogen	115-123	FUMARASE 2	Arabidopsis thaliana	10-14
20202172-12	2010	We conclude that FUM2 is required for the accumulation of fumarate in leaves, which is in turn required for rapid nitrogen assimilation and growth on high nitrogen.	Nitrogen	114-122	FUMARASE 2	Arabidopsis thaliana	17-21
20202172-12	2010	We conclude that FUM2 is required for the accumulation of fumarate in leaves, which is in turn required for rapid nitrogen assimilation and growth on high nitrogen.	Nitrogen	155-163	FUMARASE 2	Arabidopsis thaliana	17-21
28258224-5	2017	Here, we used mass spectrometry analysis of a recombinant Relish-N modified with DCA by TG activity after proteolytic digestion and show that the DCA-modified Gln residues are located in the DNA-binding region of Relish-N. TG-catalyzed DCA incorporation inhibited binding of Relish-N to the Rel-responsive element in the NF-kappaB-binding DNA sequence.	Nitrogen	65-66	Relish	Drosophila melanogaster	58-64
20304912-8	2010	These findings suggest that Cys-294 of INV-E is associated with the development of the photosynthetic apparatus and the assimilation of nitrogen in Arabidopsis seedlings to control the ratio of sucrose content to hexose content.	Nitrogen	136-144	alkaline/neutral invertase	Arabidopsis thaliana	39-44
21360884-7	2010	When COD/N were 6-7, it can meet the requirement for carbon source during aerobic denitrification, the removal rate of nitrate nitrogen and COD were up to 96%, 85% respectively.	Nitrogen	9-10	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	5-8
21360884-7	2010	When COD/N were 6-7, it can meet the requirement for carbon source during aerobic denitrification, the removal rate of nitrate nitrogen and COD were up to 96%, 85% respectively.	Nitrogen	9-10	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	140-143
21360884-7	2010	When COD/N were 6-7, it can meet the requirement for carbon source during aerobic denitrification, the removal rate of nitrate nitrogen and COD were up to 96%, 85% respectively.	Nitrogen	127-135	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	5-8
28258224-5	2017	Here, we used mass spectrometry analysis of a recombinant Relish-N modified with DCA by TG activity after proteolytic digestion and show that the DCA-modified Gln residues are located in the DNA-binding region of Relish-N. TG-catalyzed DCA incorporation inhibited binding of Relish-N to the Rel-responsive element in the NF-kappaB-binding DNA sequence.	Nitrogen	65-66	Transglutaminase	Drosophila melanogaster	88-90
20800523-1	2010	Carbamoyl phosphate synthetase 1 (CPS1) plays a paramount role in liver ureagenesis since it catalyzes the first and rate-limiting step of the urea cycle, the major pathway for nitrogen disposal in humans.	Nitrogen	177-185	carbamoyl-phosphate synthase 1	Homo sapiens	0-32
20394349-2	2010	The pyridine nitrogen in PLP in the wild-type enzyme is unprotonated due to interaction with Arg219, a rare feature among PLP-dependent enzymes.	Nitrogen	13-21	pyridoxal phosphatase	Homo sapiens	25-28
20394349-2	2010	The pyridine nitrogen in PLP in the wild-type enzyme is unprotonated due to interaction with Arg219, a rare feature among PLP-dependent enzymes.	Nitrogen	13-21	pyridoxal phosphatase	Homo sapiens	122-125
20394349-4	2010	In this form of the enzyme, the PLP-pyridine nitrogen is protonated.	Nitrogen	45-53	pyridoxal phosphatase	Homo sapiens	32-35
20800523-1	2010	Carbamoyl phosphate synthetase 1 (CPS1) plays a paramount role in liver ureagenesis since it catalyzes the first and rate-limiting step of the urea cycle, the major pathway for nitrogen disposal in humans.	Nitrogen	177-185	carbamoyl-phosphate synthase 1	Homo sapiens	34-38
28258224-5	2017	Here, we used mass spectrometry analysis of a recombinant Relish-N modified with DCA by TG activity after proteolytic digestion and show that the DCA-modified Gln residues are located in the DNA-binding region of Relish-N. TG-catalyzed DCA incorporation inhibited binding of Relish-N to the Rel-responsive element in the NF-kappaB-binding DNA sequence.	Nitrogen	65-66	Relish	Drosophila melanogaster	213-219
20964401-2	2010	The observed NQR frequencies, quadrupole coupling constants, and asymmetry parameters (eta) have been assigned to the two nitrogen positions (ring and amide) in a molecule on the basis of the intensity and multiplicity of the double resonance signals.	Nitrogen	122-130	endothelin receptor type A	Homo sapiens	87-90
20801482-5	2010	The BET surface areas of ZVINs/SBA-15 (275.1 m2 g(-1)), as determined by nitrogen adsorption-desorption isotherms, was much larger than the non-stabilized ZVINs (82.0 m2 g(-1)).	Nitrogen	73-81	delta/notch like EGF repeat containing	Homo sapiens	4-7
20082304-8	2010	This study demonstrates that cryopreservation does not affect the biological and immunological properties of SCAP, supporting the feasibility of SCAP cryopreservation in nitrogen.	Nitrogen	170-178	SREBF chaperone	Homo sapiens	145-149
28258224-5	2017	Here, we used mass spectrometry analysis of a recombinant Relish-N modified with DCA by TG activity after proteolytic digestion and show that the DCA-modified Gln residues are located in the DNA-binding region of Relish-N. TG-catalyzed DCA incorporation inhibited binding of Relish-N to the Rel-responsive element in the NF-kappaB-binding DNA sequence.	Nitrogen	65-66	Transglutaminase	Drosophila melanogaster	223-225
20136727-4	2010	Whereas single atg12a and atg12b mutants lack phenotypic consequences, atg12a atg12b double mutants senesce prematurely, are hypersensitive to nitrogen and fixed carbon starvation, and fail to accumulate autophagic bodies in the vacuole.	Nitrogen	143-151	Ubiquitin-like superfamily protein	Arabidopsis thaliana	78-84
28258224-5	2017	Here, we used mass spectrometry analysis of a recombinant Relish-N modified with DCA by TG activity after proteolytic digestion and show that the DCA-modified Gln residues are located in the DNA-binding region of Relish-N. TG-catalyzed DCA incorporation inhibited binding of Relish-N to the Rel-responsive element in the NF-kappaB-binding DNA sequence.	Nitrogen	65-66	Relish	Drosophila melanogaster	213-219
20883019-4	2010	We find that the early actinides (Pa-Np) are characterized by localized f orbitals and essentially ionic bonding, whereas the f orbitals in the later members of the series (Pu, Am) exhibit significant interaction and spin delocalization into the carbon- and nitrogen-based ligand orbitals.	Nitrogen	258-266	adenosine deaminase 2	Homo sapiens	34-39
28332657-1	2017	The present investigation describes the synergistic role of Li4(BH4)(NH2)3 and ZrFe2 in the hydrogen storage behaviour of a Li-Mg-N-H hydride system.	Nitrogen	69-70	lipase family member N	Homo sapiens	60-63
20647741-5	2010	This requirement for Gcn2 and Gcn4 distinguishes amino-acid starvation induced autophagy from classic macroautophagy: Macroautophagic flux in response to nitrogen starvation is only partly diminished in gcn2Delta and gcn4Delta cells.	Nitrogen	154-162	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	30-34
20307061-2	2010	In this study, nitrogen and argon isotherms in MOFs and zeolites (most of them having ultra-micropores) were predicted by grand canonical Monte Carlo (GCMC) simulations and used as pseudoexperimental data to evaluate the BET method for these structures.	Nitrogen	15-23	delta/notch like EGF repeat containing	Homo sapiens	221-224
20307061-3	2010	The BET surface areas calculated from the simulated nitrogen and argon isotherms agree well with the accessible surface areas obtained directly from crystal structures in a geometric fashion.	Nitrogen	52-60	delta/notch like EGF repeat containing	Homo sapiens	4-7
28013361-4	2017	Compared to WT mice, Dmp1-hWNT16 TG mice exhibited significantly higher whole-body, spine and femoral aBMD, BMC and trabecular (BV/TV, Tb.N, and Tb.Th) and cortical (bone area and thickness) parameters in both male and female at 12 weeks of age.	Nitrogen	28-29	dentin matrix protein 1	Mus musculus	21-25
19951703-11	2010	In conclusion, we found that the N-glycosylation has an important role in the folding of UGT1A9.	Nitrogen	33-34	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	89-95
21137731-0	2010	Light extraction efficiency enhancement of GaN-based light emitting diodes on n-GaN layer using a SiO2 photonic quasi-crystal overgrowth.	Nitrogen	15-16	gigaxonin	Homo sapiens	43-46
21137731-0	2010	Light extraction efficiency enhancement of GaN-based light emitting diodes on n-GaN layer using a SiO2 photonic quasi-crystal overgrowth.	Nitrogen	15-16	gigaxonin	Homo sapiens	80-83
20219371-2	2010	A SAR study of the substituents on carboxamide nitrogen afforded the N-(1-naphthyl)methylcarboxamide derivative 23 as the most potent selective PPARgamma modulator.	Nitrogen	47-55	peroxisome proliferator activated receptor gamma	Mus musculus	144-153
28056417-3	2017	Nitrogen is important for plant growth, and nitrate reductase (NR) is a key plant enzyme that catalyzes nitrogen assimilation.	Nitrogen	0-8	inducible nitrate reductase [NADH] 1	Glycine max	63-65
20699397-5	2010	In addition, SR45 is involved in the control of Glc-responsive gene expression, as the mutant displays enhanced repression of photosynthetic and nitrogen metabolism genes and overinduction of starch and anthocyanin biosynthesis genes.	Nitrogen	145-153	arginine/serine-rich 45	Arabidopsis thaliana	13-17
28056417-3	2017	Nitrogen is important for plant growth, and nitrate reductase (NR) is a key plant enzyme that catalyzes nitrogen assimilation.	Nitrogen	104-112	inducible nitrate reductase [NADH] 1	Glycine max	44-61
20437156-5	2010	The clpP mutant derived from D39 (serotype 2) exhibited a higher sensitivity to oxidative stresses such as reactive oxygen intermediates, reactive nitrogen intermediates, and H(2)O(2), but no sensitivity to osmotic stress (NaCl) and pH.	Nitrogen	147-155	caseinolytic mitochondrial matrix peptidase proteolytic subunit	Mus musculus	4-8
28056417-3	2017	Nitrogen is important for plant growth, and nitrate reductase (NR) is a key plant enzyme that catalyzes nitrogen assimilation.	Nitrogen	104-112	inducible nitrate reductase [NADH] 1	Glycine max	63-65
20936147-0	2010	Mus308 processes oxygen and nitrogen ethylation DNA damage in germ cells of Drosophila.	Nitrogen	28-36	DNA polymerase theta	Drosophila melanogaster	0-6
27731335-6	2017	We previously reported a novel N-acylation reaction for an acyl-CoA synthetase (AcsA) that originally catalyzes the formation of a thioester bond between an acid and CoA, yielding acyl-CoA.	Nitrogen	31-32	acyl-CoA synthetase short chain family member 2	Homo sapiens	59-78
20936147-5	2010	Our results indicate that Mus308 is necessary for the processing of oxygen and N-ethylation damage, for the survival of fertilized eggs depending on the level of induced DNA damage, and for an influence of the DNA damage neighbouring sequence.	Nitrogen	79-80	DNA polymerase theta	Drosophila melanogaster	26-32
19937361-9	2010	Creatinine clearance was higher in N-IgAN than IgAN patients (89.4 vs. 74.4 ml/min; P &lt; 0.001).	Nitrogen	35-36	IGAN1	Homo sapiens	37-41
27731335-6	2017	We previously reported a novel N-acylation reaction for an acyl-CoA synthetase (AcsA) that originally catalyzes the formation of a thioester bond between an acid and CoA, yielding acyl-CoA.	Nitrogen	31-32	acyl-CoA synthetase short chain family member 2	Homo sapiens	80-84
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	14-22	GRAS family transcription factor family protein	Arabidopsis thaliana	146-149
20110329-6	2010	Moreover, we show that in crb mutant cells, ectopic N activity correlates with an increase in N and Delta endocytosis.	Nitrogen	52-53	crumbs	Drosophila melanogaster	26-29
19879340-4	2010	The deduced pre-IL-22 has 190 amino acid residues containing a secretory signal peptide from amino acids 1-33 and several potential N-glycosylation sites.	Nitrogen	132-133	interleukin 22	Bos taurus	16-21
19916568-1	2010	Quantum modeling of the N7(G) alkylation of guanine-cytosine (G-C) base pair by sulfur (HD) and nitrogen mustard (HN2) was performed by using the Density Functional Theory (DFT) BPW91/6-31G++DP procedure.	Nitrogen	96-104	MT-RNR2 like 2 (pseudogene)	Homo sapiens	114-117
20707372-1	2010	A mild method is presented for the formation of N-acylated oxazolidinones that employs acid fluorides and mild bases, such as (i)Pr(2)NEt and NEt(3).	Nitrogen	48-49	tetraspanin 2	Homo sapiens	142-148
20395135-2	2010	The as-prepared BNP-TiO(2) samples are characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), nitrogen-adsorption measurement and UV-Vis spectroscopy.	Nitrogen	121-129	natriuretic peptide B	Homo sapiens	16-19
20395135-3	2010	The results show that BNP-TiO(2) possesses single anatase phase with mesopore structures, and nitrogen and phosphorus contained in original crop seeds are self-doped into the lattice as anions and cations, respectively.	Nitrogen	94-102	natriuretic peptide B	Homo sapiens	22-25
20890097-2	2010	Here we investigated by real time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16 and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles.	Nitrogen	140-148	Ssu1p	Saccharomyces cerevisiae S288C	132-136
20662012-3	2010	Fet3p has 11 crystallographically mapped N-linked core glycan units.	Nitrogen	41-42	ferroxidase FET3	Saccharomyces cerevisiae S288C	0-5
20005707-1	2010	A novel series of nitrogen-containing chalcones were synthesized by Mannich reaction and were screened for anti-inflammatory related activities such as inhibition of cyclooxygenase-2 (COX-2), trypsin and beta-glucuronidase.	Nitrogen	18-26	glucuronidase beta	Homo sapiens	204-222
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	14-22	GRAS family transcription factor family protein	Arabidopsis thaliana	231-234
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	342-350	GRAS family transcription factor family protein	Arabidopsis thaliana	146-149
20006580-0	2010	N-linked glycosylation determines cell surface expression of two-pore-domain K+ channel TRESK.	Nitrogen	0-1	potassium channel, two pore domain subfamily K, member 18 L homeolog	Xenopus laevis	88-93
20704717-0	2010	Modeling the global effect of the basic-leucine zipper transcription factor 1 (bZIP1) on nitrogen and light regulation in Arabidopsis.	Nitrogen	89-97	basic leucine-zipper 1	Arabidopsis thaliana	34-77
20704717-0	2010	Modeling the global effect of the basic-leucine zipper transcription factor 1 (bZIP1) on nitrogen and light regulation in Arabidopsis.	Nitrogen	89-97	basic leucine-zipper 1	Arabidopsis thaliana	79-84
20006580-3	2010	Two-electrode voltage-clamp recordings from Xenopus oocytes revealed that current amplitudes of N-glycosylation mutants were reduced by 80% as compared to wildtype TRESK.	Nitrogen	96-97	potassium channel, two pore domain subfamily K, member 18 L homeolog	Xenopus laevis	164-169
28327546-0	2017	Missense mutations near the N-glycosylation site of the A2 domain lead to various intracellular trafficking defects in coagulation factor VIII.	Nitrogen	28-29	coagulation factor VIII	Homo sapiens	119-142
20018744-3	2010	To uncover the role of protein flexibility and alterations in protein conformation in molecular recognition by Gbetagamma, a method for site-specific (15)N-labeling of Gbeta-Trp residue backbone and indole amines in insect cells was developed.	Nitrogen	154-155	succinate-CoA ligase GDP-forming subunit beta	Homo sapiens	111-116
20673036-1	2010	BACKGROUND: The slope of phase III (single breath nitrogen test), an index of ventilation inhomogeneity, has been used for early detection of COPD.	Nitrogen	50-58	COPD	Homo sapiens	142-146
28327546-3	2017	Here we characterize how hemophilia mutations near the unused N-glycosylation site of the A2 domain (N582) of FVIII affect protein conformation and intracellular trafficking.	Nitrogen	62-63	coagulation factor VIII	Homo sapiens	110-115
26920112-0	2017	Nitrogen-doped graphene-chitosan matrix based efficient chemiluminescent immunosensor for detection of chicken interleukin-4.	Nitrogen	0-8	interleukin 4	Gallus gallus	111-124
20543007-8	2010	On the basis of the spatial proximity and germline sequence, we reintroduced the consensus N-glycosylation site in H-CDR2 which was found in the original antibody, anticipating that the carbohydrate moiety would shield the aggregation "hot spot" in H-CDR3 while not interfering with antigen binding.	Nitrogen	91-92	cerebellar degeneration related protein 2	Homo sapiens	117-121
20543007-8	2010	On the basis of the spatial proximity and germline sequence, we reintroduced the consensus N-glycosylation site in H-CDR2 which was found in the original antibody, anticipating that the carbohydrate moiety would shield the aggregation "hot spot" in H-CDR3 while not interfering with antigen binding.	Nitrogen	91-92	CDR3	Homo sapiens	251-255
21030793-6	2010	The recombinant prolactin was secreted into the medium as an N-linked glycosylated (31 kDa) or non-glycosylated (27 kDa) protein.	Nitrogen	61-62	prolactin	Canis lupus familiaris	16-25
19895667-2	2010	In this study, we investigated whether elevation of the endogenous mGluR2/3 ligand N-acetyl-aspartatylglutamate (NAAG) levels by the N-acetylated-alpha-linked-acidic dipeptidase inhibitor 2-(phosphonomethyl)pentanedioic acid (2-PMPA) attenuates cocaine self-administration and cocaine-induced reinstatement of drug seeking.	Nitrogen	83-84	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	67-73
20407008-0	2010	Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor.	Nitrogen	8-9	glucagon like peptide 1 receptor	Homo sapiens	87-119
28215986-12	2017	N-glycosylation of CXCR3 influences the ligand-receptor interaction between CXCR3 and CXCL10.	Nitrogen	0-1	chemokine (C-X-C motif) ligand 10	Mus musculus	86-92
20407008-2	2010	Like other family members, the GLP-1 receptor is a glycosylated membrane protein that contains three potential sites for N-linked glycosylation within the functionally important extracellular amino-terminal domain.	Nitrogen	121-122	glucagon like peptide 1 receptor	Homo sapiens	31-45
20407008-10	2010	These data suggest that N-linked glycosylation of the GLP-1 receptor is important for its normal folding and trafficking to the cell surface.	Nitrogen	24-25	glucagon like peptide 1 receptor	Homo sapiens	54-68
20438597-6	2010	RESULTS: In 70.6% of the D-BC group and 70.2% of the N-BC group, VUR resolved completely after the first injection (P = 0.977).	Nitrogen	53-54	VUR	Homo sapiens	65-68
19893285-8	2010	Our results suggested that there was a strain difference in CYP-dependent diazepam N-demethylation in the rat kidney, which is different from the finding in liver microsomes.	Nitrogen	83-84	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	60-63
19811453-2	2009	In the present study, we have shown that the previously uncharacterized PDI family member TMX4 (thioredoxin-like transmembrane 4) is an N-glycosylated type I membrane protein that localizes to the ER.	Nitrogen	136-137	prolyl 4-hydroxylase subunit beta	Homo sapiens	72-75
20640414-0	2010	Inferring the evolutionary history of Mo-dependent nitrogen fixation from phylogenetic studies of nifK and nifDK.	Nitrogen	51-59	nucleolar protein interacting with the FHA domain of MKI67	Homo sapiens	98-102
20379804-2	2010	Coagulation factor VIII (FVIII) is a glycoprotein which has extensive post-translational modification by N-linked glycosylation.	Nitrogen	105-106	coagulation factor VIII	Homo sapiens	0-23
28112927-6	2017	A series of N-methylated amino derivatives, which are unable to undergo such tautomerism, were equal in potency to the phenoxy analogues and demonstrated selectivity for the liver enzyme hCE1.	Nitrogen	12-13	carboxylesterase 1	Homo sapiens	187-191
19758985-3	2009	In vitro, an 18-amino acid segment, residues 595-612, immediately upstream of the C-terminal endoplasmic reticulum targeting sequence is required for N-glycosylation of Asn(594), which permits COX-2 protein to enter the endoplasmic reticulum-associated protein degradation system.	Nitrogen	150-151	cytochrome c oxidase II, mitochondrial	Mus musculus	193-198
20589574-7	2010	Topology prediction shows there are one N-glycosylation site, two Casein kinase II phosphorylation sites, and a Amidation site in the EIF1 protein of the giant panda and black bear.	Nitrogen	40-41	eukaryotic translation initiation factor 1	Ailuropoda melanoleuca	134-138
28102675-8	2017	The amine is proposed to perform a nucleophilic attack at a terminal eta2-carboxylate ligand of the zirconium catalyst, followed by a C-O bond cleavage step, with an intermediate proton transfer from nitrogen to oxygen facilitated by an additional equivalent of amine.	Nitrogen	200-208	DNA polymerase iota	Homo sapiens	69-73
19796941-1	2009	Piperazinyl-glutamate-pyrimidines were prepared with oxygen, nitrogen, and sulfur substitution at the 4-position of the pyrimidine leading to highly potent P2Y12 antagonists.	Nitrogen	61-69	purinergic receptor P2Y12	Homo sapiens	156-161
20458271-6	2010	In a mouse model of renal IRI, a deficiency in TGF-beta1 expression increased the severity of renal injury, as indicated by more severe renal tubular damage, higher levels of serum creatinine or blood urea nitrogen in TGF-beta1 deficient mice as compared with those in wild-type controls.	Nitrogen	206-214	transforming growth factor, beta 1	Mus musculus	47-56
19828315-6	2009	Lysosomal membrane proteins Lamp1 and Lamp2 show increased molecular weights in patients" myoblasts due to differential N-glycosylation.	Nitrogen	120-121	lysosomal associated membrane protein 1	Homo sapiens	28-33
28106395-5	2017	Sterically bulky isocyanides, such as tert-butyl or 1-adamantyl isocyanides, inhibit bending at the isocyanide nitrogen atoms, a requirement for formation of eta2-iminoketenyl structures.	Nitrogen	111-119	DNA polymerase iota	Homo sapiens	158-162
20458271-6	2010	In a mouse model of renal IRI, a deficiency in TGF-beta1 expression increased the severity of renal injury, as indicated by more severe renal tubular damage, higher levels of serum creatinine or blood urea nitrogen in TGF-beta1 deficient mice as compared with those in wild-type controls.	Nitrogen	206-214	transforming growth factor, beta 1	Mus musculus	218-227
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	271-279	phosphoprotein phosphatase 2A catalytic subunit PPH21	Saccharomyces cerevisiae S288C	33-38
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	271-279	Gat1p	Saccharomyces cerevisiae S288C	111-115
19795058-6	2009	The results of gel electrophoresis indicated that ABP-SS was able to condense pDNA efficiently at an N/P ratio of 6 and could be degraded by reducing agent DTT.	Nitrogen	80-81	amine oxidase copper containing 1	Homo sapiens	50-53
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	232-236
20502620-2	2009	Specifically, our recent studies have provided evidence that the reduction of E-cadherin N-glycosylation promoted the recruitment of stabilizing components, vinculin and serine/threonine protein phosphatase 2A (PP2A), to adherens junctions (AJs) and enhanced the association of AJs with the actin cytoskeleton.	Nitrogen	89-90	vinculin	Homo sapiens	157-165
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	296-304	phosphoprotein phosphatase 2A catalytic subunit PPH21	Saccharomyces cerevisiae S288C	33-38
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	296-304	Gat1p	Saccharomyces cerevisiae S288C	111-115
20378551-5	2010	We show that all four N-glycosylation enzymes tested (beta-1,2-N-acetylglucosaminyltransferase I, beta-1,2-N-acetylglucosaminyltransferase II, 1,4-galactosyltransferase I, and alpha-2,6-sialyltransferase I) form Golgi-localized homodimers.	Nitrogen	22-23	beta-1,4-galactosyltransferase 7	Homo sapiens	147-170
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	148-156	Gat1p	Saccharomyces cerevisiae S288C	232-236
20358221-5	2010	Experiments using PP2A inhibitors, together with PP2Ac expression profiles under conditions that affect tuberization indicate that high sucrose/nitrogen ratio, which promotes tuber formation, increases the transcript levels of Patatin and Pin2, by increasing the activity of PP2As without affecting PP2Ac mRNA or protein levels.	Nitrogen	144-152	proteinase inhibitor type-2	Solanum tuberosum	239-243
19326247-2	2009	Dichlobenil and BAM were combined nitrogen sources in the MPN tubes, which were scored positive at concentrations &lt;75% after 1 month incubation.	Nitrogen	34-42	structural maintenance of chromosomes 3	Homo sapiens	16-19
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	148-156	Gat1p	Saccharomyces cerevisiae S288C	232-236
28103859-9	2017	ActRIIB-Fc increased bone mass also in vertebrae (BV/TV +20%, Tb.N +30%, P &lt; 0.05) but the effects were more modest.	Nitrogen	65-66	activin receptor IIB	Mus musculus	0-7
19928283-0	2009	Nitrogen ion induced 2D-GaN layer formation of GaAs (001) surface.	Nitrogen	0-8	gigaxonin	Homo sapiens	24-27
19928283-1	2009	This study demonstrates the formation of two-dimensional GaN on GaAs (001) surface by bombardment of nitrogen ions at room temperature.	Nitrogen	101-109	gigaxonin	Homo sapiens	57-60
19443574-5	2009	We expressed a form of hCG that lacks three of its four N-linked glycosylation sites and tested its efficacy as an antagonist.	Nitrogen	56-57	chorionic gonadotropin subunit beta 5	Homo sapiens	23-26
20233714-7	2010	In addition to inducing amino acid biosynthetic genes, Gcn4p in conjunction with Gln3p activates genes required for the assimilation of secondary nitrogen sources such as gamma-aminobutyric acid (GABA).	Nitrogen	146-154	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	55-60
20535429-8	2010	A positive correlation was found between plasma BNP levels with age, blood urea nitrogen (BUN) and NIHSS and a negative correlation was found between plasma BNP levels and GCS.	Nitrogen	80-88	natriuretic peptide B	Homo sapiens	48-51
27789075-2	2017	The addition of a long alkyl chain, such as decyl or dodecyl, to the nitrogen led to the production of highly potent inhibitors of alpha-l-rhamnosidase; it also caused broad inhibition spectrum against beta-glucosidase and beta-galactosidase.	Nitrogen	69-77	galactosidase beta 1	Homo sapiens	223-241
20348404-10	2010	CONCLUSIONS: This study demonstrated hemopexin to be a model protein for studying liver-specific N-glycosylation.	Nitrogen	2-3	hemopexin	Homo sapiens	37-46
27343203-7	2017	RESULTS: A hitherto unknown IgE-binding site was mapped on the stalk region of CD23, and the non-N-glycosylated monomeric version of CD23 was superior in IgE binding compared with glycosylated CD23.	Nitrogen	97-98	Fc epsilon receptor II	Homo sapiens	133-137
20369811-5	2010	The addition of a methyl group on the nitrogen results in a secondary competitive pathway at the gamma-C site.	Nitrogen	38-46	interleukin 2 receptor subunit gamma	Homo sapiens	97-104
27343203-7	2017	RESULTS: A hitherto unknown IgE-binding site was mapped on the stalk region of CD23, and the non-N-glycosylated monomeric version of CD23 was superior in IgE binding compared with glycosylated CD23.	Nitrogen	97-98	Fc epsilon receptor II	Homo sapiens	133-137
20331962-5	2010	In addition, we tested if ERK-1/2 affected the N/OFQ-induced inhibition of the I(K) by using whole-cell patch-clamp recordings in acutely dissociated rat parietal cortical neurons.	Nitrogen	47-48	mitogen activated protein kinase 3	Rattus norvegicus	26-33
20331962-6	2010	We found that N/OFQ, PDBu, and IDB increased the amount of phosphorylated ERK-1/2 and Elk-1; U0126, a specific inhibitor for ERK-1/2, attenuated the inhibitory effect of N/OFQ on the I(K).	Nitrogen	14-15	mitogen activated protein kinase 3	Rattus norvegicus	74-81
27726052-1	2017	A novel fluorescence method for sensitive and selective detection of phosphate was developed based on near infrared emission Ag2S QDs/ Metal - Organic Shell Composite via the deposition of metal-organic (zinc-nitrogen) coordination shell around Ag2S QDs .	Nitrogen	209-217	angiotensin II receptor type 1	Homo sapiens	125-129
20331962-6	2010	We found that N/OFQ, PDBu, and IDB increased the amount of phosphorylated ERK-1/2 and Elk-1; U0126, a specific inhibitor for ERK-1/2, attenuated the inhibitory effect of N/OFQ on the I(K).	Nitrogen	14-15	ETS transcription factor ELK1	Rattus norvegicus	86-91
20331962-6	2010	We found that N/OFQ, PDBu, and IDB increased the amount of phosphorylated ERK-1/2 and Elk-1; U0126, a specific inhibitor for ERK-1/2, attenuated the inhibitory effect of N/OFQ on the I(K).	Nitrogen	14-15	mitogen activated protein kinase 3	Rattus norvegicus	125-132
20331962-6	2010	We found that N/OFQ, PDBu, and IDB increased the amount of phosphorylated ERK-1/2 and Elk-1; U0126, a specific inhibitor for ERK-1/2, attenuated the inhibitory effect of N/OFQ on the I(K).	Nitrogen	170-171	mitogen activated protein kinase 3	Rattus norvegicus	74-81
20331962-6	2010	We found that N/OFQ, PDBu, and IDB increased the amount of phosphorylated ERK-1/2 and Elk-1; U0126, a specific inhibitor for ERK-1/2, attenuated the inhibitory effect of N/OFQ on the I(K).	Nitrogen	170-171	ETS transcription factor ELK1	Rattus norvegicus	86-91
20331962-6	2010	We found that N/OFQ, PDBu, and IDB increased the amount of phosphorylated ERK-1/2 and Elk-1; U0126, a specific inhibitor for ERK-1/2, attenuated the inhibitory effect of N/OFQ on the I(K).	Nitrogen	170-171	mitogen activated protein kinase 3	Rattus norvegicus	125-132
20331969-1	2010	Campylobacter jejuni contains a post-translational N-glycosylation system in which a STT3 homologue, PglB, functions as the oligosaccharyltransferase.	Nitrogen	51-52	epiphycan	Homo sapiens	101-105
27726052-1	2017	A novel fluorescence method for sensitive and selective detection of phosphate was developed based on near infrared emission Ag2S QDs/ Metal - Organic Shell Composite via the deposition of metal-organic (zinc-nitrogen) coordination shell around Ag2S QDs .	Nitrogen	209-217	angiotensin II receptor type 1	Homo sapiens	245-249
19951703-0	2010	N-Glycosylation plays a role in protein folding of human UGT1A9.	Nitrogen	0-1	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	57-63
29634169-5	2017	The BET specific surface area of the carbon material prepared by the heat treatment at 800 degrees C for 1 h under flowing N2 was related to the pretreatment conditions, and the specific surface areas of the samples were found to be related to the lignin percentage.	Nitrogen	123-125	delta/notch like EGF repeat containing	Homo sapiens	4-7
19951703-3	2010	In the present study, we investigated the role of N-glycosylation in the function of human UGT1A9.	Nitrogen	50-51	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	91-97
28081948-1	2017	Given that Cav3.2 T-type Ca2+ channels were functionally regulated by asparagine (N)-linked glycosylation, we examined effects of high glucose on the function of Cav3.2, known to regulate secretory function, in neuroendocrine-like differentiated prostate cancer LNCaP cells.	Nitrogen	81-84	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	11-17
20154027-1	2010	Npr2, a putative "nitrogen permease regulator" and homolog of the human tumor suppressor NPRL2, was found to interact with Grr1, the F-box component of the SCF(Grr1) (Skp1-cullin-F-box protein complex containing Grr1) E3 ubiquitin ligase, by mass spectrometry-based multidimensional protein identification technology.	Nitrogen	18-26	natriuretic peptide receptor 2	Homo sapiens	0-4
20154027-7	2010	Npr2 is required for robust growth in defined medium containing ammonium or urea as a nitrogen source but not for growth on rich medium.	Nitrogen	86-94	natriuretic peptide receptor 2	Homo sapiens	0-4
20154027-9	2010	Together, these data indicate that Npr2 is a phosphorylation-dependent target of the SCF(Grr1) E3 ubiquitin ligase that plays a role in cell growth on some nitrogen sources.	Nitrogen	156-164	natriuretic peptide receptor 2	Homo sapiens	35-39
28081948-2	2017	High glucose accelerated the increased channel function and overexpression of Cav3.2 during neuroendocrine differentiation, the former prevented by enzymatic inhibition of N-glycosylation and cleavage of N-glycans.	Nitrogen	172-173	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	78-84
20153225-6	2010	The pyridine nitrogen (N(AR)) of lig17 was capable of interacting with His95 (CDK4) through hydrogen bonding.	Nitrogen	13-21	cyclin dependent kinase 4	Homo sapiens	78-82
28228088-10	2017	CONCLUSION: The bio-screening data, in vitro and in vivo anti-inflammatory activity and COX-2 enzymatic assay revealed that few N-substituteed aryl/heteroaryl-pyrazol-1-yl) benzene sulfonamides showed potent activity and compound 5e showed more potent COX-2 inhibit activity than that of parent drug, celecoxib and the standard, flufenamic acid.	Nitrogen	2-3	cox2	Gossypium hirsutum	88-93
20150444-5	2010	Doc2 proteins bound to N-ethylmaleimide-sensitive factor attachment receptor (SNARE) complexes in competition with synaptotagmin-1.	Nitrogen	23-24	synaptotagmin 1	Homo sapiens	115-130
19910111-6	2010	The results of UV/vis/DRS spectra and SPV revealed that proper doping of nitrogen could expand the response of photoelectrodes towards visible light and diminish the recombination of photo-generated holes and electrons, respectively.	Nitrogen	73-81	sushi repeat containing protein X-linked	Homo sapiens	22-25
28228088-10	2017	CONCLUSION: The bio-screening data, in vitro and in vivo anti-inflammatory activity and COX-2 enzymatic assay revealed that few N-substituteed aryl/heteroaryl-pyrazol-1-yl) benzene sulfonamides showed potent activity and compound 5e showed more potent COX-2 inhibit activity than that of parent drug, celecoxib and the standard, flufenamic acid.	Nitrogen	2-3	cox2	Gossypium hirsutum	252-257
27923447-7	2017	Moreover, fat-1 transgenic mice treated with N-IgY showed significant downregulation of genes involved in cholesterol-induced hepatic stellate cell activation (Tgfb1, Tlr4, Col1a1, Col1a2, and Timp2).	Nitrogen	45-46	transforming growth factor, beta 1	Mus musculus	160-165
27923447-7	2017	Moreover, fat-1 transgenic mice treated with N-IgY showed significant downregulation of genes involved in cholesterol-induced hepatic stellate cell activation (Tgfb1, Tlr4, Col1a1, Col1a2, and Timp2).	Nitrogen	45-46	collagen, type I, alpha 2	Mus musculus	181-187
27923447-7	2017	Moreover, fat-1 transgenic mice treated with N-IgY showed significant downregulation of genes involved in cholesterol-induced hepatic stellate cell activation (Tgfb1, Tlr4, Col1a1, Col1a2, and Timp2).	Nitrogen	45-46	tissue inhibitor of metalloproteinase 2	Mus musculus	193-198
28178702-7	2017	The silencing of ALG13-is2 by specific siRNAs induces an altered N-linked glycosylation pattern of nephrin, as demonstrated by the presence of an additional immunostaining band of about 130 kD.	Nitrogen	42-43	ALG13 UDP-N-acetylglucosaminyltransferase subunit	Homo sapiens	17-22
27504800-7	2017	In serum, elevated levels of blood urea nitrogen and creatinine were reduced in anti-OPN Ab-treated mice compared with vehicle.	Nitrogen	40-48	secreted phosphoprotein 1	Mus musculus	85-88
28503408-10	2017	These data are consistent with a hypothesis that APAP hepatotoxicity occurs with altered calcium metabolism, activation of nNOS leading to increased reactive nitrogen formation, and mitochondrial dysfunction.	Nitrogen	158-166	nitric oxide synthase 1, neuronal	Mus musculus	123-127
20142497-8	2010	Analysis of the expression of this miR393/AFB3 module, revealed an incoherent feed-forward mechanism that is induced by nitrate and repressed by N metabolites generated by nitrate reduction and assimilation.	Nitrogen	145-146	auxin signaling F-box 3	Arabidopsis thaliana	42-46
20358819-5	2010	Nitrogen cycle for different farm fields showed that field surplus nitrogen ranged from (102 +/- 68) to (303 +/- 134) kg x (hm2 x a)(-1) among different farms.	Nitrogen	0-8	cholinergic receptor muscarinic 2	Homo sapiens	124-127
20358819-5	2010	Nitrogen cycle for different farm fields showed that field surplus nitrogen ranged from (102 +/- 68) to (303 +/- 134) kg x (hm2 x a)(-1) among different farms.	Nitrogen	67-75	cholinergic receptor muscarinic 2	Homo sapiens	124-127
20083147-7	2010	The changes in N-glycosylation observed were dependent on the catalytic activity of GnTIII, as the expression of catalytically inactive GnTIII mutants did not show a significant effect on N-glycosylation.	Nitrogen	15-16	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	84-90
20083147-7	2010	The changes in N-glycosylation observed were dependent on the catalytic activity of GnTIII, as the expression of catalytically inactive GnTIII mutants did not show a significant effect on N-glycosylation.	Nitrogen	15-16	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	136-142
20083147-7	2010	The changes in N-glycosylation observed were dependent on the catalytic activity of GnTIII, as the expression of catalytically inactive GnTIII mutants did not show a significant effect on N-glycosylation.	Nitrogen	188-189	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	84-90
19598164-4	2009	N(2)-adsorption (BET) analysis resulted in a tremendous enhancement of surface area (101 m(2)/g) of BVPE stationary phases compared to typical organic monoliths (approximately 20 m(2)/g), indicating the presence of a considerable amount of mesopores.	Nitrogen	0-4	delta/notch like EGF repeat containing	Homo sapiens	17-20
19655847-0	2009	A Hirshfeld interpretation of the charge, spin distribution, and polarity of the dipole moment of the open shell (3Sigma-) nitrogen halides: NF, NCl, and NBr.	Nitrogen	123-131	nucleolin	Homo sapiens	145-148
19525426-3	2009	Comparison of OmPRLR1 and OmPRLR2 revealed conserved features of cytokine class I receptors (CKR1): a WS domain and transmembrane domain, two pairs of cysteines and N-glycosylation motifs in the extracellular region, CKR1 boxes I and II, and three tyrosines in the intracellular region.	Nitrogen	165-166	C-C motif chemokine receptor 1	Homo sapiens	93-97
19158842-7	2009	Characterization of the plasmin-derived 97 kDa fragment with domain-specific collagen XVII antibodies, heparin binding and N-glycosylation studies indicates that the N-terminus is located approximately at AA 515 and the C-terminus N-terminally from AA 1,421.	Nitrogen	123-124	plasminogen	Homo sapiens	24-31
19357295-4	2009	In LPS-challenged macrophages and cytokine-stimulated endothelial cells obtained from COX-2(Neo/Neo) mice, COX-2 expression was reduced 70-90%, and these mice developed a mild renal phenotype compared with COX-2 mice possessing an active site mutation (COX-2(Y385F/Y385F)), with minimal signs of renal dysfunction as measured by FITC-inulin clearance and blood urea nitrogen.	Nitrogen	366-374	prostaglandin-endoperoxide synthase 2	Mus musculus	86-91
19357295-4	2009	In LPS-challenged macrophages and cytokine-stimulated endothelial cells obtained from COX-2(Neo/Neo) mice, COX-2 expression was reduced 70-90%, and these mice developed a mild renal phenotype compared with COX-2 mice possessing an active site mutation (COX-2(Y385F/Y385F)), with minimal signs of renal dysfunction as measured by FITC-inulin clearance and blood urea nitrogen.	Nitrogen	366-374	prostaglandin-endoperoxide synthase 2	Mus musculus	107-112
19357295-4	2009	In LPS-challenged macrophages and cytokine-stimulated endothelial cells obtained from COX-2(Neo/Neo) mice, COX-2 expression was reduced 70-90%, and these mice developed a mild renal phenotype compared with COX-2 mice possessing an active site mutation (COX-2(Y385F/Y385F)), with minimal signs of renal dysfunction as measured by FITC-inulin clearance and blood urea nitrogen.	Nitrogen	366-374	prostaglandin-endoperoxide synthase 2	Mus musculus	107-112
19357295-4	2009	In LPS-challenged macrophages and cytokine-stimulated endothelial cells obtained from COX-2(Neo/Neo) mice, COX-2 expression was reduced 70-90%, and these mice developed a mild renal phenotype compared with COX-2 mice possessing an active site mutation (COX-2(Y385F/Y385F)), with minimal signs of renal dysfunction as measured by FITC-inulin clearance and blood urea nitrogen.	Nitrogen	366-374	prostaglandin-endoperoxide synthase 2	Mus musculus	107-112
19208354-9	2009	The intracellular transport and enzymatic activity, but not correct folding, of LPH-G1363S were partially restored by expression at 20 degrees C. However, a form of LPH that contains the mutations G1363S and N1361A, which eliminates the N-glycosylation site, did not restore the features of wild-type LPH.	Nitrogen	208-209	lactase	Homo sapiens	80-83
19208354-9	2009	The intracellular transport and enzymatic activity, but not correct folding, of LPH-G1363S were partially restored by expression at 20 degrees C. However, a form of LPH that contains the mutations G1363S and N1361A, which eliminates the N-glycosylation site, did not restore the features of wild-type LPH.	Nitrogen	208-209	lactase	Homo sapiens	165-168
19208354-9	2009	The intracellular transport and enzymatic activity, but not correct folding, of LPH-G1363S were partially restored by expression at 20 degrees C. However, a form of LPH that contains the mutations G1363S and N1361A, which eliminates the N-glycosylation site, did not restore the features of wild-type LPH.	Nitrogen	208-209	lactase	Homo sapiens	165-168
19422674-3	2009	RESULTS: We found that the hyperactive cells produced mainly non-complex N-glycosylated POMC, whereas in the basally active cells POMC was mostly complex N-glycosylated.	Nitrogen	154-155	proopiomelanocortin L homeolog	Xenopus laevis	130-134
19416536-4	2009	RESULTS: The four N-linked glycosylation sequons within the activation peptide were all occupied in bovine TAFI, similar to human TAFI, while the sequon located within the enzyme moiety of the bovine protein was non-glycosylated.	Nitrogen	18-19	carboxypeptidase B2	Homo sapiens	130-134
18937066-2	2009	Using the 1C11 neuronal bioaminergic differentiation model and a glycomics approach, we show here a correlation between differential PrP(C) N-glycosylations in 1C11(5-HT) serotonergic and 1C11(NE) noradrenergic cells compared to their 1C11 precursor cells and a variation of the glycogenome expression status in these cells.	Nitrogen	140-141	prion protein	Mus musculus	133-139
19233899-4	2009	These kinetic properties of compounds 1 and 7 against TK-2 could be accounted for by molecular modeling showing that two hydrogen bonds can be formed between the thiourea nitrogens of compound 7 and the oxygens of the gamma-phosphate of ATP.	Nitrogen	171-180	thymidine kinase 2	Homo sapiens	54-58
19352533-3	2009	Thermolysis of a hexanes solution of , under nitrogen atmosphere, produces the chelated complex (eta(5):eta(1)-C(5)Me(4)CH(2)PPh(2))Re(CO)(2) () in good yield.	Nitrogen	45-53	endothelin receptor type A	Homo sapiens	97-100
19352533-3	2009	Thermolysis of a hexanes solution of , under nitrogen atmosphere, produces the chelated complex (eta(5):eta(1)-C(5)Me(4)CH(2)PPh(2))Re(CO)(2) () in good yield.	Nitrogen	45-53	endothelin receptor type A	Homo sapiens	104-107
19323453-0	2009	Insights into the structural basis of N2 and O6 substituted guanine derivatives as cyclin-dependent kinase 2 (CDK2) inhibitors: prediction of the binding modes and potency of the inhibitors by docking and ONIOM calculations.	Nitrogen	38-40	cyclin dependent kinase 2	Homo sapiens	83-108
19323453-0	2009	Insights into the structural basis of N2 and O6 substituted guanine derivatives as cyclin-dependent kinase 2 (CDK2) inhibitors: prediction of the binding modes and potency of the inhibitors by docking and ONIOM calculations.	Nitrogen	38-40	cyclin dependent kinase 2	Homo sapiens	110-114
19323453-1	2009	N2 and O6 substituted guanine derivatives are well-known as potent and selective CDK2 inhibitors.	Nitrogen	0-2	cyclin dependent kinase 2	Homo sapiens	81-85
19254717-3	2009	Applying this approach results in a quick identification of essential N-glycosylation sites of a heavily glycosylated neuroglycoprotein Lingo-1, which are sufficient for the support of its surface expression.	Nitrogen	70-71	leucine rich repeat and Ig domain containing 1	Homo sapiens	136-143
19295141-7	2009	Using a novel technique for targeted activation of neurons, we show that the highly stereotyped wing expansion motor patterns can be initiated by stimulation of N(CCAP), a small network of central neurons that regulates the release of bursicon.	Nitrogen	161-162	Bursicon	Drosophila melanogaster	235-243
19054802-3	2009	It has been proposed that beta-N-acetylglucosaminidase (GlcNAcase), a hexosaminidase in the Golgi membrane which removes a terminal N-acetylglucosamine (GlcNAc), might contribute to simple N-glycosylation in several insects and insect-derived cells except S2 cells.	Nitrogen	31-32	O-GlcNAcase	Drosophila melanogaster	56-65
19054802-5	2009	Using high-performance liquid chromatography (HPLC) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analyses, we found that the N-glycosylation patterns of human erythropoietin (hEPO) secreted by stably transfected S2 cells were more complex following GlcNAcase suppression, which generated N-glycan structures with a terminal GlcNAc and/or galactose.	Nitrogen	176-177	O-GlcNAcase	Drosophila melanogaster	300-309
19054802-6	2009	These data demonstrate that GlcNAcase may be an important factor in the formation of paucimannosidic core N-glycans in Drosophila S2 cells and suggest that it may be possible to express complex glycoproteins in engineered Drosophila S2 cells by suppressing GlcNAcase in the N-glycosylation pathway.	Nitrogen	31-32	O-GlcNAcase	Drosophila melanogaster	257-266
19233806-13	2009	Amino acid apparent whole-tract digestibilities were greater when on RC than G diets and intermediate when on CRC for all amino acids, with the exception of Met, which was reduced in cows on both red clover diets compared with G. It is proposed that the PPO trait could show more benefit to ruminants if red clover was fed in combination with lesser N-containing forages or if red clover was bred to contain less N.	Nitrogen	350-351	protoporphyrinogen oxidase	Bos taurus	254-257
19233806-13	2009	Amino acid apparent whole-tract digestibilities were greater when on RC than G diets and intermediate when on CRC for all amino acids, with the exception of Met, which was reduced in cows on both red clover diets compared with G. It is proposed that the PPO trait could show more benefit to ruminants if red clover was fed in combination with lesser N-containing forages or if red clover was bred to contain less N.	Nitrogen	413-414	protoporphyrinogen oxidase	Bos taurus	254-257
19909832-11	2010	Indeed, site-directed mutagenesis of two furin N-glycosylation sites, Asn(387) and Asn(440), abrogated furin activation and this mutant was unable to rescue ADAMTS5 processing in furin-deficient cells.	Nitrogen	47-48	furin, paired basic amino acid cleaving enzyme	Homo sapiens	41-46
19961860-6	2010	Thr189 is also identified as a crucial residue where hydrogen bonding to Asp187 keeps the latter in an optimal position for hydrogen bonding to the pyridoxal nitrogen of PLP.	Nitrogen	158-166	pyridoxal phosphatase	Homo sapiens	170-173
19814657-4	2010	We also review recently published work that has revealed that one member of this family, UGT3A1, has a unique enzymatic function: N-acetylglucosaminidation.	Nitrogen	130-131	UDP glycosyltransferase family 3 member A1	Homo sapiens	89-95
20022931-5	2010	In the absence of human MRAP coexpression, N-glycosylation of at least one of the two sites was necessary for MC2R cell surface expression.	Nitrogen	43-44	melanocortin 2 receptor	Homo sapiens	110-114
20022931-8	2010	Taken together, these results indicate that the absence of MC2R N-glycosylation abrogates to a large extent MC2R cell surface expression in the absence of MRAPs, whereas when MC2R is N-glycosylated, it can be expressed at the plasma membrane without MRAP assistance.	Nitrogen	64-65	melanocortin 2 receptor	Homo sapiens	108-112
20022931-8	2010	Taken together, these results indicate that the absence of MC2R N-glycosylation abrogates to a large extent MC2R cell surface expression in the absence of MRAPs, whereas when MC2R is N-glycosylated, it can be expressed at the plasma membrane without MRAP assistance.	Nitrogen	64-65	melanocortin 2 receptor	Homo sapiens	108-112
19171765-9	2009	Because glycosylation affects the flexibility, movement, and interactions of surface molecules, we tested if selectively removing conserved N-glycoslyation sites in the constant regions of TCR alpha or beta chains could increase the functional avidity of T cells transduced with such modified TCRs.	Nitrogen	140-141	T cell receptor alpha constant	Homo sapiens	189-198
19061865-5	2009	Here, we show that Lap3, a soluble cytosolic cysteine protease, is spatially associated with Ape1 and selectively transported to the vacuole during nitrogen starvation.	Nitrogen	148-156	bleomycin hydrolase	Saccharomyces cerevisiae S288C	19-23
29749183-3	2017	The results indicated that nitrogen deposition significantly decreased MBC and MBN in the 0-10 cm soil layer, and as N de-position increased, the inhibition effect was enhanced.	Nitrogen	27-35	proteinase 3	Homo sapiens	79-82
19858116-0	2009	Wheat (Triticum aestivum) NAM proteins regulate the translocation of iron, zinc, and nitrogen compounds from vegetative tissues to grain.	Nitrogen	85-93	NAC domain-containing protein 20	Triticum aestivum	26-29
29749183-5	2017	The influence of N deposition on MBC and MBN was weakened with the increase of soil depth.	Nitrogen	17-18	proteinase 3	Homo sapiens	41-44
29749198-5	2017	The treatment of subsoiling tillage coupling with 225 kg hm-2 nitrogen, was best for soil nitrogen transformation while the treatment of subsoiling tillage coupling with 330 kg hm-2 nitrogen, had the highest corn yield.	Nitrogen	62-70	Putative anthocyanidin reductase	Zea mays	57-61
29749198-5	2017	The treatment of subsoiling tillage coupling with 225 kg hm-2 nitrogen, was best for soil nitrogen transformation while the treatment of subsoiling tillage coupling with 330 kg hm-2 nitrogen, had the highest corn yield.	Nitrogen	90-98	Putative anthocyanidin reductase	Zea mays	57-61
27899413-3	2016	TORC1 negatively regulates autophagy according to nitrogen availability.	Nitrogen	50-58	CREB regulated transcription coactivator 1	Homo sapiens	0-5
19046908-5	2009	The results show that Zn(2+) has a strong effect on the NQR parameters (chi, eta) of proximal nitrogen in contrast with the remote nitrogen.	Nitrogen	94-102	endothelin receptor type A	Homo sapiens	77-80
19046908-8	2009	Finally, we predicted (chi=1.95 MHz, eta=0.84) for proximal nitrogen, (chi=2.38 MHz, eta=0.07) for remote nitrogen and (chi=1.28 MHz, eta=0.22) for Zn in superoxide dismutase.	Nitrogen	60-68	endothelin receptor type A	Homo sapiens	37-40
27565712-6	2016	Further study on the regulatory mechanisms suggested that membrane-proximal N-glycosylation is critical for intermolecular interactions between integrin beta1 and other cell membrane proteins, such as syndecan-4 and epidermal growth factor receptor.	Nitrogen	76-77	syndecan 4	Homo sapiens	201-211
18995860-7	2008	Critical comments are made about some reported relationships between gamma(s)(d), obtained from IGC, and the BET surface area or pore volume of AC as determined from nitrogen adsorption at 77K.	Nitrogen	166-174	delta/notch like EGF repeat containing	Homo sapiens	109-112
26842796-4	2016	Different theoretical models have been employed to describe the carrier transport mechanisms of the device in the OFF and ON states measured in different gas atmospheres on the basis of the experimental I-V results, and the carrier transport of the device in the ON state measured in air is very different from that measured in N2 and low O2 concentrations due to the participation of oxygen vacancies in the trapping and de-trapping processes of electrons into and out of the Ag2S/PVK heterointerface.	Nitrogen	328-330	angiotensin II receptor type 1	Homo sapiens	477-481
19054131-2	2008	It is especially useful for low abundance proteins, for example the GATA-factors (Gln3, Gat1) which activate nitrogen catabolite repression (NCR)-sensitive transcription.	Nitrogen	109-117	Gat1p	Saccharomyces cerevisiae S288C	88-92
27769499-1	2016	In this report, the design of two novel nitrogen mustard-based DNA cross-linking agents with fluorophores incorporated into the structure (TN-A and TN-B) is disclosed.	Nitrogen	40-48	C-type lectin domain family 3 member B	Homo sapiens	139-143
18778408-4	2008	We found that both the N- and O-glycosylation mutants are apically sorted, associate to detergent-resistant microdomains and are able to oligomerize, like the wild-type proteins, suggesting that glycosylation does not have a direct role in GPI-AP oligomerization and apical sorting.	Nitrogen	23-24	glucose-6-phosphate isomerase	Homo sapiens	240-243
28144326-2	2016	Sorption measurements with nitrogen gas at 77 K revealed BET-surface areas up to 650 m2/g.	Nitrogen	27-35	delta/notch like EGF repeat containing	Homo sapiens	57-60
18588327-2	2008	Nitrogen adsorption measurement interpreted by BET, DR, HK, and NLDFT methods reveals these nanostructured activated carbons exhibit a high surface area of up to 4000 m2/g, a micropore volume up to approximately 1.75 mL/g, and an average pore size of approximately 10-20 angstroms.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	47-50
18939794-2	2008	The binary systems dealt with in this paper show as a common feature the existence of a tricritical point at the SmA-to-N phase transition, all of which reported elsewhere.	Nitrogen	120-121	survival of motor neuron 1, telomeric	Homo sapiens	113-116
27911384-4	2016	Recently, we uncovered that glucose-mediated N-glycosylation of SCAP is a prerequisite condition for the exit of SCAP/SREBP from the ER and movement to the Golgi.	Nitrogen	45-46	SREBF chaperone	Homo sapiens	64-68
18713738-0	2008	Phosphorylation of the yeast nitrate transporter Ynt1 is essential for delivery to the plasma membrane during nitrogen limitation.	Nitrogen	110-118	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	49-53
18713738-2	2008	It is highly regulated by the nitrogen source, by being down-regulated in response to glutamine by repression of the YNT1 gene and Ynt1 ubiquitinylation, endocytosis, and vacuolar degradation.	Nitrogen	30-38	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	117-121
18713738-2	2008	It is highly regulated by the nitrogen source, by being down-regulated in response to glutamine by repression of the YNT1 gene and Ynt1 ubiquitinylation, endocytosis, and vacuolar degradation.	Nitrogen	30-38	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	131-135
27911384-4	2016	Recently, we uncovered that glucose-mediated N-glycosylation of SCAP is a prerequisite condition for the exit of SCAP/SREBP from the ER and movement to the Golgi.	Nitrogen	45-46	SREBF chaperone	Homo sapiens	113-117
18713738-3	2008	On the contrary, we show that nitrogen limitation stabilizes Ynt1 levels at the plasma membrane, requiring phosphorylation of the transporter.	Nitrogen	30-38	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	61-65
18713738-6	2008	We found that, under nitrogen limitation, Ynt1 phosphorylation is essential for rapid induction of nitrate assimilation genes.	Nitrogen	21-29	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	42-46
27911384-5	2016	N-glycosylation stabilizes SCAP and directs SCAP/SREBP trafficking.	Nitrogen	0-1	SREBF chaperone	Homo sapiens	27-31
18713738-7	2008	Our results suggest that, under nitrogen limitation, phosphorylation prevents Ynt1 delivery from the secretion route to the vacuole, which, aided by reduced ubiquitinylation, accumulates Ynt1 at the plasma membrane.	Nitrogen	32-40	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	78-82
18713738-7	2008	Our results suggest that, under nitrogen limitation, phosphorylation prevents Ynt1 delivery from the secretion route to the vacuole, which, aided by reduced ubiquitinylation, accumulates Ynt1 at the plasma membrane.	Nitrogen	32-40	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	187-191
27911384-5	2016	N-glycosylation stabilizes SCAP and directs SCAP/SREBP trafficking.	Nitrogen	0-1	SREBF chaperone	Homo sapiens	44-48
29964663-2	2016	The results showed that dry and wet nitrogen deposition of Daiyun Mountain National Nature Reserve was 2.30 kg hm-2 and 14.79 kg hm-2 from March to October in 2015.	Nitrogen	36-44	cholinergic receptor muscarinic 2	Homo sapiens	111-115
18815241-7	2008	After adjustment for age, gender, and race/ethnicity, uric acid and blood urea nitrogen were significantly associated with cystatin C levels.	Nitrogen	79-87	cystatin C	Homo sapiens	123-133
18815241-8	2008	CONCLUSIONS: Serum cystatin C is significantly related to gender, age, race/ethnicity, uric acid, and blood urea nitrogen in adolescents.	Nitrogen	113-121	cystatin C	Homo sapiens	19-29
18725511-7	2008	The highest contribution for the N-demethylation as calculated from the enzyme kinetic data, were obtained for CYP2B6 (R,S-MDMA), CYP1A2 (R-MDMA), and CYP2B6 (S-MDMA).	Nitrogen	33-34	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	111-117
18725511-7	2008	The highest contribution for the N-demethylation as calculated from the enzyme kinetic data, were obtained for CYP2B6 (R,S-MDMA), CYP1A2 (R-MDMA), and CYP2B6 (S-MDMA).	Nitrogen	33-34	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	151-157
29964663-2	2016	The results showed that dry and wet nitrogen deposition of Daiyun Mountain National Nature Reserve was 2.30 kg hm-2 and 14.79 kg hm-2 from March to October in 2015.	Nitrogen	36-44	cholinergic receptor muscarinic 2	Homo sapiens	129-133
29964663-3	2016	53% of dry deposition was in the form of dissolved organic nitrogen (DON, 1.21 kg hm-2).	Nitrogen	59-67	cholinergic receptor muscarinic 2	Homo sapiens	82-86
27723332-4	2016	These observations are consistent with the formation of R3N+-C(R)-H   NR3 type hydrogen bonds between the nitrogen atom of the ionophore and the hydrogen atoms in the alpha position to the positively charged quaternary ammonium center of NBu4+.	Nitrogen	106-114	glutamate ionotropic receptor NMDA type subunit 2B	Homo sapiens	70-73
18708352-1	2008	Multiple pathways link expression of PTR2, the transporter of di- and tripeptides in the yeast Saccharomyces cerevisiae, to the availability and quality of nitrogen sources.	Nitrogen	156-164	Ptr2p	Saccharomyces cerevisiae S288C	37-41
18703501-7	2008	Mass spectrometry experiments showed that CA IX contains an intramolecular disulfide bridge (Cys(119)-Cys(299)) and a unique N-linked glycosylation site (Asn(309)) that bears high mannose-type glycan structures.	Nitrogen	125-126	carbonic anhydrase 9	Homo sapiens	42-47
27629431-4	2016	Although both autophagic and proteasomal systems contribute to the degradation of ULK1, under prolonged nitrogen deprivation, its level was still reduced in ATG7 knockout cells, and only initially stabilized in cells treated with the lysosomal or proteasomal inhibitors.	Nitrogen	104-112	unc-51 like autophagy activating kinase 1	Homo sapiens	82-86
27847511-3	2016	Here, we conducted a phylogenetically controlled meta-analysis using data from 111 published studies encompassing the responses of 129 alien plants to global warming, increased precipitation, N deposition, and CO2 enrichment.	Nitrogen	192-193	COP9 signalosome subunit 2	Homo sapiens	135-140
18420026-4	2008	Bioinformatics analysis showed there were two putative N-glycosylation sites within human NECL1 at positions N25LS and N290KS and within mouse Necl1 at positions N23LS and N288KS, respectively.	Nitrogen	55-56	cell adhesion molecule 3	Homo sapiens	90-95
18420026-4	2008	Bioinformatics analysis showed there were two putative N-glycosylation sites within human NECL1 at positions N25LS and N290KS and within mouse Necl1 at positions N23LS and N288KS, respectively.	Nitrogen	55-56	cell adhesion molecule 3	Mus musculus	143-148
27749147-5	2016	In this study, we have investigated the role of stearoyl-acyl carrier protein desaturase isoform C (SACPD-C), a soybean enzyme that catalyzes the conversion of stearic acid into oleic acid, which is expressed in developing seeds and in nitrogen-fixing nodules.	Nitrogen	236-244	stearoyl-ACP desaturase	Glycine max	48-98
18353697-4	2008	The putative signal sequence consists of amino acids 1-24 of the beta-galactosidase precursor protein, which contains seven potential N-linked glycosylation sites, as in the human protein.	Nitrogen	134-135	galactosidase beta 1	Homo sapiens	65-83
27749147-5	2016	In this study, we have investigated the role of stearoyl-acyl carrier protein desaturase isoform C (SACPD-C), a soybean enzyme that catalyzes the conversion of stearic acid into oleic acid, which is expressed in developing seeds and in nitrogen-fixing nodules.	Nitrogen	236-244	stearoyl-ACP desaturase	Glycine max	100-107
27578781-5	2016	Sequence analysis indicates that the Scw ligand contains two N-glycosylation motifs: one being highly conserved between BMP2/4- and BMP5/6/7/8-type ligands, and the other being Scw ligand specific.	Nitrogen	61-62	bone morphogenetic protein 2	Homo sapiens	120-126
18222180-7	2008	Our data are consistent with a specific role of kidney Acy1 in the salvage of amino acids originating from systemic degradation of N-acetylated proteins.	Nitrogen	131-132	aminoacylase 1	Homo sapiens	55-59
27578781-5	2016	Sequence analysis indicates that the Scw ligand contains two N-glycosylation motifs: one being highly conserved between BMP2/4- and BMP5/6/7/8-type ligands, and the other being Scw ligand specific.	Nitrogen	61-62	bone morphogenetic protein 5	Homo sapiens	132-140
27578781-7	2016	In contrast, N-glycosylation modifications of Gbb or Scw ligands reduce the consistency of PCV development.	Nitrogen	13-14	glass bottom boat	Drosophila melanogaster	46-49
27546880-9	2016	Interestingly, the outbred strains CD-1 and Swiss Webster displayed considerably larger interindividual variation than inbred strains BALB/c and CD57BL/6, suggesting a strong hereditable component of the observed plasma N-glycome.	Nitrogen	220-221	CD6 antigen	Mus musculus	145-153
18342636-5	2008	The ring nitrogen of PLP is involved in a H-bonding with C309, but is apparently not protonated.	Nitrogen	9-17	pyridoxal phosphatase	Homo sapiens	21-24
18342636-9	2008	C303 of hSDH and C309 of cSDH which are H-bonding partner of the ring nitrogen of PLP were mutated to alanine and their kinetic parameters were also determined.	Nitrogen	70-78	serine dehydratase like	Homo sapiens	25-29
18342636-9	2008	C303 of hSDH and C309 of cSDH which are H-bonding partner of the ring nitrogen of PLP were mutated to alanine and their kinetic parameters were also determined.	Nitrogen	70-78	pyridoxal phosphatase	Homo sapiens	82-85
27396293-7	2016	The results suggested that immobilized nitrifier pellets combined with high influent COD/N ratios could effectively improve the nitrogen removal performance in CWs.	Nitrogen	128-136	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	85-88
18408886-6	2008	Essential structural requirements for OCTN2 inhibition include a constantly positively charged nitrogen atom and a carboxyl, nitrile or ester group connected by a 2-4-atom linker.	Nitrogen	95-103	solute carrier family 22 member 5	Homo sapiens	38-43
27582506-0	2016	Effects of N-Glycosylation of the human cation channel TRPA1 on agonist-sensitivity.	Nitrogen	11-12	transient receptor potential cation channel subfamily A member 1	Homo sapiens	55-60
18238858-8	2008	These data suggest that UGT2B10 is likely the most active UGT isoform in human liver for the N-glucuronidation of TSNAs.	Nitrogen	93-94	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	24-27
27582506-4	2016	TRPA1 possesses two putative N-linked glycosylation sites at N747 and N753 that have not yet been studied in detail.	Nitrogen	29-30	transient receptor potential cation channel subfamily A member 1	Homo sapiens	0-5
18302366-3	2008	In particular, the transition states for both forms are stabilized by the intramolecular hydrogen bonds between the prolyl nitrogen and the N-H group of the Phe3 residue.	Nitrogen	123-131	dihydrolipoamide dehydrogenase	Homo sapiens	157-161
18302366-3	2008	In particular, the transition states for both forms are stabilized by the intramolecular hydrogen bonds between the prolyl nitrogen and the N-H group of the Phe3 residue.	Nitrogen	140-141	dihydrolipoamide dehydrogenase	Homo sapiens	157-161
18322210-0	2008	Identification of an N-linked glycosylation in the C4 region of HIV-1 envelope gp120 that is critical for recognition of neighboring CD4 T cell epitopes.	Nitrogen	21-22	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	79-84
20391715-3	2010	The result showed that the average, minimum and maximum nitrogen loads of farmland were 214.02 kg/hm2, 10.64 kg/hm2 and 5996.26 kg/hm2 respectively and near half of farmland was threaten by nitrogen load of livestock manure, accounting for 42.14% of the total farmland.	Nitrogen	56-64	cholinergic receptor muscarinic 2	Homo sapiens	98-101
20391715-3	2010	The result showed that the average, minimum and maximum nitrogen loads of farmland were 214.02 kg/hm2, 10.64 kg/hm2 and 5996.26 kg/hm2 respectively and near half of farmland was threaten by nitrogen load of livestock manure, accounting for 42.14% of the total farmland.	Nitrogen	56-64	cholinergic receptor muscarinic 2	Homo sapiens	112-115
20391715-3	2010	The result showed that the average, minimum and maximum nitrogen loads of farmland were 214.02 kg/hm2, 10.64 kg/hm2 and 5996.26 kg/hm2 respectively and near half of farmland was threaten by nitrogen load of livestock manure, accounting for 42.14% of the total farmland.	Nitrogen	56-64	cholinergic receptor muscarinic 2	Homo sapiens	112-115
27469001-7	2016	Using small interfering RNA-mediated knockdown in human cells and assessing the stoichiometry of the enzyme system reconstituted in vitro, we provide evidence that NADH-cytochrome-b5 reductase 3 is the principal reductase involved in the mARC enzyme system and is an essential component of N-reductive metabolism in human cells.	Nitrogen	25-26	cytochrome b5 reductase 3	Homo sapiens	164-194
19874874-9	2010	Our present data strongly suggests that activation of the GnRH receptor in the hypothalamus is involved in stimulation of OT secretion from the rat H-N system.	Nitrogen	150-151	gonadotropin releasing hormone receptor	Rattus norvegicus	58-71
18229942-0	2008	Enantioselective synthesis of beta2-amino acids via Rh-catalyzed asymmetric hydrogenation with BoPhoz-type ligands: important influence of an N-H proton in the ligand on the enantioselectivity.	Nitrogen	142-143	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	30-35
17986252-5	2008	Three members of the VID and GID gene families, VID30/GID1, GID2, and VID28/GID5 are needed for the rapamycin or nitrogen starvation-induced degradation of the high-affinity hexose transporter Hxt7p is shown here.	Nitrogen	113-121	glucose-induced degradation complex subunit VID30	Saccharomyces cerevisiae S288C	48-53
17986252-5	2008	Three members of the VID and GID gene families, VID30/GID1, GID2, and VID28/GID5 are needed for the rapamycin or nitrogen starvation-induced degradation of the high-affinity hexose transporter Hxt7p is shown here.	Nitrogen	113-121	glucose-induced degradation complex subunit VID30	Saccharomyces cerevisiae S288C	54-58
17986252-5	2008	Three members of the VID and GID gene families, VID30/GID1, GID2, and VID28/GID5 are needed for the rapamycin or nitrogen starvation-induced degradation of the high-affinity hexose transporter Hxt7p is shown here.	Nitrogen	113-121	hexose transporter HXT7	Saccharomyces cerevisiae S288C	193-198
19759267-6	2010	Blood urea nitrogen and hematocrit were also significantly higher in Cln7(-/-) mice.	Nitrogen	11-19	major facilitator superfamily domain containing 8	Mus musculus	69-73
27056577-4	2016	The qPCR analyses of genes involved in nitrogen utilization showed that transcriptional levels of the UGA1 and DUR3 genes encoding GABA transaminase and urea transporter, respectively, are severely decreased in the AY77 cells.	Nitrogen	39-47	4-aminobutyrate transaminase	Saccharomyces cerevisiae S288C	102-106
19926722-1	2010	The Tgs proteins are structurally homologous AdoMet-dependent eukaryal enzymes that methylate the N2 atom of 7-methyl guanosine nucleotides.	Nitrogen	98-100	lin-9 DREAM MuvB core complex component	Homo sapiens	4-7
17999676-3	2008	Deletion of the genes encoding the transcriptional coactivators Rsc1p or Gcn5p impairs FLO11 transcription, which consequently leads to a loss of both haploid invasive growth and diploid pseudohyphae development upon glucose and nitrogen limitation, respectively.	Nitrogen	229-237	RSC subunit protein RSC1	Saccharomyces cerevisiae S288C	64-69
27547921-0	2016	Fluorogenic probes reveal a role of GLUT4 N-glycosylation in intracellular trafficking.	Nitrogen	42-43	solute carrier family 2 member 4	Homo sapiens	36-41
19791450-1	2008	The rotational constants and the nitrogen nuclear quadrupole coupling constants of cis-3-aminophenol and trans-3-aminophenol are determined using Fourier-transform microwave spectroscopy.	Nitrogen	33-41	suppressor of cytokine signaling 3	Homo sapiens	83-88
19961415-1	2009	An efficient method is described for production of membrane protein KCNE3 and its isotope labeled derivatives ((15)N-, (15)N-/13C-) in amounts sufficient for structural-functional investigations.	Nitrogen	115-116	potassium voltage-gated channel subfamily E regulatory subunit 3	Homo sapiens	68-73
27547921-1	2016	Glucose transporter 4 (GLUT4) is an N-glycosylated protein that maintains glucose homeostasis by regulating the protein translocation.	Nitrogen	36-37	solute carrier family 2 member 4	Homo sapiens	0-21
27547921-1	2016	Glucose transporter 4 (GLUT4) is an N-glycosylated protein that maintains glucose homeostasis by regulating the protein translocation.	Nitrogen	36-37	solute carrier family 2 member 4	Homo sapiens	23-28
18281945-16	2008	The O (eta) atom of Tyr208 provides a hydrogen bond to stabilize the closed form of loop 6 by interacting with the amide nitrogen of Ala176; these atoms are outside of hydrogen bonding distance in the open form of the enzyme.	Nitrogen	121-129	endothelin receptor type A	Homo sapiens	7-10
19934017-3	2009	Here we address these questions and show that O-N patterning is associated with the expansion and fusion of the palatal shelves and that Dlx5 is required for the O-N patterning of palatal mesenchyme.	Nitrogen	164-165	distal-less homeobox 5	Mus musculus	137-141
27519409-9	2016	Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris.	Nitrogen	188-196	aspartate transaminase AAT2	Saccharomyces cerevisiae S288C	67-71
27232923-5	2016	Those with extremely elevated BNP were older (P=0.004), with a lower body mass index (P&lt;0.0001), higher blood urea nitrogen (P=0.01), higher creatinine (P=0.005), lower cardiac output (P&lt;0.0001) and lower cardiac index (P=0.001).	Nitrogen	118-126	natriuretic peptide B	Homo sapiens	30-33
19919521-5	2009	Using nitrogen cavitation, we observed that Ang1 is localized in the cytosolic fraction whereas VEGF is found in beta-granules.	Nitrogen	6-14	angiopoietin 1	Homo sapiens	44-48
18537212-2	2008	Several theoretical studies have been published that bear on the proposed intermediates in the catalytic dinitrogen reduction reaction and their reaction characteristics, including DFT calculations on [(HIPTNCH(2)CH(2))(3)N]Mo species (HIPT =hexaisopropylterphenyl = 3,5-(2,4,6-iPr(3)C(6)H(2))(2)C(6)H(3)), which contain the actual triamidoamine ligand that is present in catalytic intermediates.	Nitrogen	105-115	cullin associated and neddylation dissociated 1	Homo sapiens	208-209
18537212-2	2008	Several theoretical studies have been published that bear on the proposed intermediates in the catalytic dinitrogen reduction reaction and their reaction characteristics, including DFT calculations on [(HIPTNCH(2)CH(2))(3)N]Mo species (HIPT =hexaisopropylterphenyl = 3,5-(2,4,6-iPr(3)C(6)H(2))(2)C(6)H(3)), which contain the actual triamidoamine ligand that is present in catalytic intermediates.	Nitrogen	105-115	cullin associated and neddylation dissociated 1	Homo sapiens	213-214
17932459-4	2008	AtATG6-AS plants produced fewer Monodansylcadaverine (MDC) and LysoTracker (LT) stained-autolysosomes in response to carbon and nitrogen starvation indicating that AtATG6 plays a role in the autophagic pathway in Arabidopsis.	Nitrogen	128-136	AUTOPHAGY 6	Arabidopsis thaliana	0-6
17932459-4	2008	AtATG6-AS plants produced fewer Monodansylcadaverine (MDC) and LysoTracker (LT) stained-autolysosomes in response to carbon and nitrogen starvation indicating that AtATG6 plays a role in the autophagic pathway in Arabidopsis.	Nitrogen	128-136	AUTOPHAGY 6	Arabidopsis thaliana	164-170
20118607-5	2009	This study focuses on the isolation of variants of Put4p, which are insensitive to repression by a preferred nitrogen source (ammonia) and their subsequent effect on proline transport and stress tolerance.	Nitrogen	109-117	proline permease PUT4	Saccharomyces cerevisiae S288C	51-56
26559224-5	2016	One of the endocytosis-deficient mutants (rme-6) took up less silver and was resistant to the acute toxicity of CIT-AgNPs compared to N2s.	Nitrogen	134-137	Receptor-mediated endocytosis protein 6	Caenorhabditis elegans	42-47
19693772-0	2009	N-glycosylation of ATF6beta is essential for its proteolytic cleavage and transcriptional repressor function to ATF6alpha.	Nitrogen	0-1	activating transcription factor 6 beta	Homo sapiens	19-27
19693772-2	2009	ATF6beta contains five evolutionarily conserved N-linked glycosylation sites and is a key transcriptional repressor of ATF6alpha, which contribute to regulating the strength and duration of ATF6-dependent ER stress response (ERSR) gene induction.	Nitrogen	48-49	activating transcription factor 6 beta	Homo sapiens	0-8
19693772-3	2009	Although it is well established that p110ATF6beta can be cleaved and generate a nuclear form of 60-kDa (p60ATF6beta) that inhibits ATF6alpha-mediated ERSR genes activation, the functional significance of p110 ATF6beta N-linked glycosylation is unknown.	Nitrogen	218-219	activating transcription factor 6 beta	Homo sapiens	41-49
18752233-3	2008	Calculations showed that both heteroatoms are capable of accelerating the ring closure by stabilizing the partial positive charge which develops at C-6 (C-2) in the transition state, with S-heterocyclic derivatives being more reactive than the corresponding N-containing compounds.	Nitrogen	258-259	complement C6	Homo sapiens	148-151
18064734-7	2008	The efficient stacking approach provides LODs (S/N = 3) of 2.41, 0.59, 0.61, and 4.22 nM for trypsin inhibitor, HSA, beta-lactoglobulin, and lysozyme, respectively.	Nitrogen	49-50	cysteine rich secretory protein LCCL domain containing 2	Homo sapiens	93-110
27297999-4	2016	The agonist EC50 and percent effect for OTR are reported and show that most N-methylations are tolerated but with some loss in potency compared to OT.	Nitrogen	76-77	oxytocin receptor	Homo sapiens	40-43
17919965-3	2008	Yeast with an activated Ras2/cAMP pathway show many phenotypes indicative of altered nitrogen uptake and metabolism; sensitivity to nitrogen starvation, low amino acid pools.	Nitrogen	85-93	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	24-28
17919965-3	2008	Yeast with an activated Ras2/cAMP pathway show many phenotypes indicative of altered nitrogen uptake and metabolism; sensitivity to nitrogen starvation, low amino acid pools.	Nitrogen	132-140	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	24-28
19501959-9	2009	Acid Red 2 by electrooxidation is due to the partial or complete cleavage of C-N bonds in C.I.	Nitrogen	79-80	adenosine deaminase RNA specific B2 (inactive)	Homo sapiens	5-10
19695216-3	2009	After (24h) induction of ischemia, xCT(-/-) mice had elevated concentrations of blood urea nitrogen and creatinine indicative of ARF, while in xCT(+/-) and xCT(+/+) mice, these parameters did not differ from the sham-operated mice.	Nitrogen	91-99	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	Mus musculus	35-38
27134014-14	2016	The mixed SAMs, constructed from a 1:1 combination of COOCH3- and N(CH3)3(+)-terminated thiols, can induce protein adsorption mainly through the electrostatic interaction.	Nitrogen	66-67	methionine adenosyltransferase 1A	Homo sapiens	10-14
19231263-0	2009	Growth hormone and growth hormone secretagogue effects on nitrogen balance and urea synthesis in steroid treated rats.	Nitrogen	58-66	gonadotropin releasing hormone receptor	Rattus norvegicus	19-33
18269793-2	2008	This concise method is able to validate prior exposure to nitrogen mustards (HN-1, HN-2, and HN-3) or sulfur mustard (HD) in a single run, which significantly reduces analysis time compared to separate runs to screen for different mustards" biomarkers based on tandem mass spectrometry.	Nitrogen	58-66	Jupiter microtubule associated homolog 1	Homo sapiens	77-81
18269793-2	2008	This concise method is able to validate prior exposure to nitrogen mustards (HN-1, HN-2, and HN-3) or sulfur mustard (HD) in a single run, which significantly reduces analysis time compared to separate runs to screen for different mustards" biomarkers based on tandem mass spectrometry.	Nitrogen	58-66	MT-RNR2 like 2 (pseudogene)	Homo sapiens	83-87
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	syntaxin 16	Homo sapiens	459-470
19231263-7	2009	Compared to prednisolone treated animals, co-administration of GH reduced CUNS by 33% (p&lt;0.01), normalized urea cycle gene expression, improved N-balance 2.5-fold, and normalized or improved organ N-contents.	Nitrogen	76-77	gonadotropin releasing hormone receptor	Rattus norvegicus	63-65
19231263-9	2009	CONCLUSION: Accelerated nitrogen wasting in the liver and other organs caused by prednisolone treatment was counteracted by treatment with either GH or its secretagogue Ipamorelin, though at the doses given less efficiently by the latter.	Nitrogen	24-32	gonadotropin releasing hormone receptor	Rattus norvegicus	146-148
27038422-8	2016	The apparent metabolizable energy corrected for nitrogen balance (AMEn) values were reduced (P &lt; 0.05) for NL2 and NL3.	Nitrogen	48-56	membrane metalloendopeptidase like 1	Homo sapiens	110-113
19620394-0	2009	Distinctive responses to nitrogen starvation in the dominant active mutants of the fission yeast Rheb GTPase.	Nitrogen	25-33	Ras homolog, mTORC1 binding	Homo sapiens	97-101
19620394-2	2009	Rhb1 (a fission yeast homolog of Rheb) regulates amino acid uptake as well as response to nitrogen starvation.	Nitrogen	90-98	Ras homolog, mTORC1 binding	Homo sapiens	33-37
19620394-6	2009	Under nitrogen-rich conditions, Rheb stimulates Tor kinase, which, in turn, suppresses the response to nitrogen starvation.	Nitrogen	6-14	Ras homolog, mTORC1 binding	Homo sapiens	32-36
19620394-6	2009	Under nitrogen-rich conditions, Rheb stimulates Tor kinase, which, in turn, suppresses the response to nitrogen starvation.	Nitrogen	103-111	Ras homolog, mTORC1 binding	Homo sapiens	32-36
19269039-8	2009	Pig IL-27 p28 has one transmembrane region, one signal peptide, and one N-glycosylation site, two Protein kinase C phosphorylation sites, three Casein kinase II phosphorylation sites and one N-myristoylation site.	Nitrogen	72-73	interleukin 27	Sus scrofa	4-13
19296044-10	2009	Serum cross-linked N-teleopeptides of type-I collagen (NTx) in MBP group at 8 months and in whole milk group at 6 months were significantly decreased from baseline.	Nitrogen	19-20	myelin basic protein	Homo sapiens	63-66
19534521-4	2009	Here we show that the pH dependence of autoproteolysis in a slow-cleaving mutant (1G) of the MUC1 SEA domain is consistent with a mechanism in which N --&gt; O acyl shift proceeds after initial protonation of the amide nitrogen.	Nitrogen	219-227	mucin 1, cell surface associated	Homo sapiens	93-97
19532999-0	2009	A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3,5-dichloro-2(1H)-pyrazinones.	Nitrogen	58-59	complement C6	Homo sapiens	63-66
19380492-0	2009	The yeast GATA factor Gat1 occupies a central position in nitrogen catabolite repression-sensitive gene activation.	Nitrogen	58-66	Gat1p	Saccharomyces cerevisiae S288C	22-26
19217702-6	2009	OUTCOMES &amp; MEASUREMENTS: The decrease in measured glomerular filtration rate (mGFR) was determined by means of linear mixed models and adjusted for age, sex, primary kidney disease, dialysis modality, smoking, cardiovascular disease, and normalized protein nitrogen appearance and additionally for proteinuria, blood pressure, and baseline mGFR.	Nitrogen	261-269	Rap guanine nucleotide exchange factor (GEF) 5	Mus musculus	82-86
19276077-0	2009	An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1,4-N-acetylglucosaminyltransferase III.	Nitrogen	3-4	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	163-198
19264785-5	2009	However, optimum 2G12 antigenicity was found when Pst1, a heavily N-glycosylated protein, was expressed with homogenous Man(8)GlcNAc(2) structures in Delta och1 Delta mnn1 Delta mnn4 yeast.	Nitrogen	66-67	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	50-54
19154763-3	2009	Microspheres were loaded with N-glycosylated recombinant GDNF and prepared using the Total Recirculation One-Machine System (TROMS).	Nitrogen	30-31	glial cell derived neurotrophic factor	Rattus norvegicus	57-61
19296678-6	2009	The rigidity of the pyrrolidine ring places the pyrrolidine ring nitrogen between the same conserved Glu and the selective residue nNOS Asp597/eNOS Asn368, which results in similar interactions observed with the alpha-amino group of dipeptide inhibitors bound to nNOS.	Nitrogen	65-73	nitric oxide synthase 1	Homo sapiens	131-135
19296678-6	2009	The rigidity of the pyrrolidine ring places the pyrrolidine ring nitrogen between the same conserved Glu and the selective residue nNOS Asp597/eNOS Asn368, which results in similar interactions observed with the alpha-amino group of dipeptide inhibitors bound to nNOS.	Nitrogen	65-73	nitric oxide synthase 1	Homo sapiens	263-267
19262426-8	2009	CONCLUSION: The absence of FMO1-mediated N-oxidation of imipramine results in enhanced central nervous system effects of the drug.	Nitrogen	2-3	flavin containing monooxygenase 1	Mus musculus	27-31
19231828-9	2009	Irradiation of 26 ([Cr{eta(6)-C(6)H(5)CH(2)(2-Py)}(CO)(3)]) also induces CO loss to immediately yield three species: the Cr-heptane solvent coordinated intermediate, a kappaN(1)-Py nitrogen chelate, and an agostic eta(2)-chelate in which the pyridine is coordinated to the metal center via a C-H agostic bond as opposed to the nitrogen lone pair.	Nitrogen	181-189	endothelin receptor type A	Homo sapiens	23-26
19231828-9	2009	Irradiation of 26 ([Cr{eta(6)-C(6)H(5)CH(2)(2-Py)}(CO)(3)]) also induces CO loss to immediately yield three species: the Cr-heptane solvent coordinated intermediate, a kappaN(1)-Py nitrogen chelate, and an agostic eta(2)-chelate in which the pyridine is coordinated to the metal center via a C-H agostic bond as opposed to the nitrogen lone pair.	Nitrogen	181-189	endothelin receptor type A	Homo sapiens	214-217
19231828-9	2009	Irradiation of 26 ([Cr{eta(6)-C(6)H(5)CH(2)(2-Py)}(CO)(3)]) also induces CO loss to immediately yield three species: the Cr-heptane solvent coordinated intermediate, a kappaN(1)-Py nitrogen chelate, and an agostic eta(2)-chelate in which the pyridine is coordinated to the metal center via a C-H agostic bond as opposed to the nitrogen lone pair.	Nitrogen	327-335	endothelin receptor type A	Homo sapiens	23-26
19231828-9	2009	Irradiation of 26 ([Cr{eta(6)-C(6)H(5)CH(2)(2-Py)}(CO)(3)]) also induces CO loss to immediately yield three species: the Cr-heptane solvent coordinated intermediate, a kappaN(1)-Py nitrogen chelate, and an agostic eta(2)-chelate in which the pyridine is coordinated to the metal center via a C-H agostic bond as opposed to the nitrogen lone pair.	Nitrogen	327-335	endothelin receptor type A	Homo sapiens	214-217
19215073-0	2009	Structural variety of alkali metal compounds containing P-E-M (E = S, Se; M = Li, Na, K) units derived from nitrogen rich heterocycles.	Nitrogen	108-116	mucin 1, cell surface associated	Homo sapiens	56-61
19241372-10	2009	(15)N-HSQC NMR spectra of modified dematin indicate that the headpiece domain is fully folded whereas the core region is primarily unfolded.	Nitrogen	4-5	dematin actin binding protein	Homo sapiens	35-42
19241374-4	2009	In this study, we determined the solution structure of the Fn14 CRD (Glu28-Ala70) by heteronuclear NMR, with a (13)C-/(15)N-labeled sample.	Nitrogen	99-100	TNF receptor superfamily member 12A	Homo sapiens	59-63
19137564-6	2009	An electron donor-electron acceptor (EDA) mechanism between the carbon of CO(2) and the nitrogen of the heterocycle and weak hydrogen bonds stabilize the complex, with important contributions from dispersion and induction forces.	Nitrogen	88-96	ectodysplasin A	Homo sapiens	37-40
19026635-5	2009	In the present study, we show that glycosylation is an essential requirement for surface nucleolin expression, since it is prevented when cells are cultured in the presence of tunicamycin, an inhibitor of N-glycosylation.	Nitrogen	205-206	nucleolin	Homo sapiens	89-98
19089010-1	2009	The mechanism of N-dealkylation of N-cyclopropyl-N-methylaniline () catalyzed by cytochrome P450 (P450) was investigated using density functional theory.	Nitrogen	17-18	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	81-103
19090677-9	2009	Crystallographic analysis reveals the formation of a stable, novel covalent bond for PMSF between the catalytic nitrogen of the N-terminal proline and the sulfur of PMSF with complete, well-defined electron density in all three active sites of the MIF homotrimer.	Nitrogen	112-120	macrophage migration inhibitory factor	Homo sapiens	248-251
17761201-7	2008	Sulfur and phosphorus deprivation increased this expression level, while nitrogen starvation repressed APS reductase mRNA transcript and protein levels.	Nitrogen	73-81	chalcone reductase CHR1	Glycine max	107-116
17825428-6	2007	However, the CD59 protein has a potential N-glycosylation site at the Asn35 residue.	Nitrogen	42-43	CD59 glycoprotein	Ictalurus punctatus	13-17
17804483-5	2007	In the Smad3-KO mice, however, the defects that were improved were renal hypertrophy, mesangial matrix expansion, fibronectin overproduction, glomerular basement membrane thickening, plasma creatinine, and the blood urea nitrogen.	Nitrogen	221-229	SMAD family member 3	Mus musculus	7-12
17704055-6	2007	In addition, the diploid Flo11p-dependent pseudohyphal growth during nitrogen limitation was CPC2/ASC1-dependent.	Nitrogen	69-77	solute carrier family 7 member 10	Homo sapiens	98-102
17670897-5	2007	ICAM-1(-/-) mice were significantly resistant to LPS-mediated ARF, as opposed to CD18-def mice, which developed severe ARF, as did wild-type controls (48 h blood urea nitrogen 143 +/- 31.5, 70.8 +/- 24.4, and 185 +/- 16.6 mg/dl in wild-type, ICAM-1(-/-), and CD18-def mice, respectively, P &lt; 0.05).	Nitrogen	167-175	intercellular adhesion molecule 1	Mus musculus	0-6
17889671-5	2007	N-glycosylated MUC1-C increases galectin-3 mRNA levels by suppressing expression of the microRNA miR-322 and thereby stabilizing galectin-3 transcripts.	Nitrogen	0-1	mucin 1, cell surface associated	Homo sapiens	15-19
17889671-5	2007	N-glycosylated MUC1-C increases galectin-3 mRNA levels by suppressing expression of the microRNA miR-322 and thereby stabilizing galectin-3 transcripts.	Nitrogen	0-1	galectin 3	Homo sapiens	32-42
17889671-5	2007	N-glycosylated MUC1-C increases galectin-3 mRNA levels by suppressing expression of the microRNA miR-322 and thereby stabilizing galectin-3 transcripts.	Nitrogen	0-1	galectin 3	Homo sapiens	129-139
18064756-3	2007	Pig integrin beta6 gene (2367bp) encodes a polypeptide of 788 amino acids consisting of 9 potential N-linked glycosylation sites, 3 Glycosaminoglycan attachment sites, a cGMP-dependent protein kinase phosphorylation site, 10 Protein kinase C phosphorylation sites, 2 EGF-like domains and 2 cysteine-rich regions.	Nitrogen	100-101	integrin subunit beta 6	Sus scrofa	4-18
17584861-3	2007	The Xenopus Lefty proprotein contains a single N-linked glycosylation motif in the mature domain and two potential cleavage sites that would be expected to produce long (Xlefty(L)) and short (Xlefty(S)) isoforms.	Nitrogen	47-48	left-right determination factor L homeolog	Xenopus laevis	12-17
17584861-6	2007	When secreted from oocytes, vertebrate Lefty molecules were N-linked glycosylated.	Nitrogen	60-61	left-right determination factor L homeolog	Xenopus laevis	39-44
17537852-13	2007	Overexpression of dynamitin reduced N accumulation in the perinuclear region, which further supports microtubule components in N trafficking.	Nitrogen	36-37	dynactin subunit 2	Homo sapiens	18-27
17693533-6	2007	Transcriptional upregulation of AMT1;5 in nitrogen-deficient rhizodermal and root hair cells and the ability of AMT1;5 to transport ammonium in yeast suggested that AMT1;5 accounts for the remaining uptake capacity in qko.	Nitrogen	42-50	ammonium permease MEP1	Saccharomyces cerevisiae S288C	32-36
17582821-3	2007	In this report, we determined the structure of the bromodomain from human brahma-related gene 1 (BRG1) protein, a subunit of an ATP-dependent switching/sucrose nonfermenting (SWI/SNF) remodeling complex, and have also characterized its in vitro interaction with N-acetylated lysine peptides from histones.	Nitrogen	180-181	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	74-95
17582821-3	2007	In this report, we determined the structure of the bromodomain from human brahma-related gene 1 (BRG1) protein, a subunit of an ATP-dependent switching/sucrose nonfermenting (SWI/SNF) remodeling complex, and have also characterized its in vitro interaction with N-acetylated lysine peptides from histones.	Nitrogen	180-181	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	97-101
17512009-5	2007	By the combined effect, Tyr170-O(eta) moves a total of 10.5 A, resulting in the formation of hydrogen bonds with the nitrogen of amide linkage in Ald (closed form).	Nitrogen	117-125	endothelin receptor type A	Homo sapiens	33-36
17493577-0	2007	A novel function of VCP (valosin-containing protein; p97) in the control of N-glycosylation of proteins in the endoplasmic reticulum.	Nitrogen	76-77	valosin containing protein	Homo sapiens	20-23
17493577-0	2007	A novel function of VCP (valosin-containing protein; p97) in the control of N-glycosylation of proteins in the endoplasmic reticulum.	Nitrogen	76-77	valosin containing protein	Homo sapiens	25-51
17493577-0	2007	A novel function of VCP (valosin-containing protein; p97) in the control of N-glycosylation of proteins in the endoplasmic reticulum.	Nitrogen	76-77	valosin containing protein	Homo sapiens	53-56
17440807-6	2007	A highly conserved structure of the CD14 protein with respect to the leucine-rich repeats domain and the N-glycosylation sites was observed between species.	Nitrogen	105-106	CD14 molecule	Homo sapiens	36-40
17488285-6	2007	A panel of mAbs to adenylyltransferase was used to demonstrate that the cellular nitrogen status indicators, PII and PII-UMP, probably bind in the central regulatory domain to stimulate the adenylylation and deadenylylation reactions, respectively.	Nitrogen	81-89	adenylyltransferase	Escherichia coli	19-38
17508782-6	2007	The conservative structural motif embracing one of the potential sites of the gp120 N-linked glycosylation was detected, which seems to be a promising target for the HIV-1 drug design.	Nitrogen	84-85	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	78-83
17498579-9	2007	B-type natriuretic peptide quartile remained highly predictive of mortality even after adjustment for age, gender, systolic blood pressure, blood urea nitrogen, creatinine, sodium, pulse, and dyspnea at rest, Q4 versus Q1 (adjusted odds ratio 2.23 [95% confidence interval 1.91 to 2.62, p &lt; 0.0001]).	Nitrogen	151-159	natriuretic peptide B	Homo sapiens	0-26
17317686-8	2007	The lack of N-sulfation in heparin markedly reduced HGF-inducing activity, whereas 2-O-desulfation or 6-O-desulation had a lesser influence.	Nitrogen	12-13	hepatocyte growth factor	Homo sapiens	52-55
18429381-4	2007	The purpose of this study was to investigate the in vitro toxicity of the nitrogen mustard mechlorethamine (HN2) in four cell models: CEM-SS human T cells, A431 human skin epithelial cells, rat hippocampal astrocytes and rat pleural mesothelial cells.	Nitrogen	74-82	MT-RNR2 like 2 (pseudogene)	Homo sapiens	108-111
17264154-6	2007	We propose a new model for OST function where ribophorin I acts as a chaperone or escort to promote the N-glycosylation of selected substrates by the catalytic STT3 subunits.	Nitrogen	104-105	ribophorin I	Homo sapiens	46-58
17593721-3	2007	ENC1 showed higher BET surface area, higher nitrogen-accessible micropore volume, and lower mass of extractable organic chemicals, including quantifiable polycyclic aromatic hydrocarbons (PAHs),while the two chars showed identical surface oxygen/ carbon (O/C) ratio.	Nitrogen	44-52	ectodermal-neural cortex 1	Homo sapiens	0-4
17144906-2	2007	As recent findings have indicated the presence of Ca(v)2.1 (P/Q-type) channels and soluble N-ethyl-maleimide-sensitive fusion protein attachment protein receptors (SNAREs) in the cholesterol-enriched microdomains of neuroendocrine and neuronal cells, we investigated whether molecules known to modulate neurosecretion, such as the heterotrimeric G proteins and neuronal calcium sensor-1 (NCS-1), are also localized in these microdomains.	Nitrogen	91-92	neuronal calcium sensor 1	Homo sapiens	361-386
17144906-2	2007	As recent findings have indicated the presence of Ca(v)2.1 (P/Q-type) channels and soluble N-ethyl-maleimide-sensitive fusion protein attachment protein receptors (SNAREs) in the cholesterol-enriched microdomains of neuroendocrine and neuronal cells, we investigated whether molecules known to modulate neurosecretion, such as the heterotrimeric G proteins and neuronal calcium sensor-1 (NCS-1), are also localized in these microdomains.	Nitrogen	91-92	neuronal calcium sensor 1	Homo sapiens	388-393
27328012-2	2016	In the present work, Li4(NH2)3BH4 doped Mg(NH2)2-2LiH was formed by milling the 2LiNH2-MgH2-0.2LiBH4 composite and posterior annealing under hydrogen pressure to reduce the kinetic barrier of the Li-Mg-N-H system.	Nitrogen	25-26	lipase family member N	Homo sapiens	21-24
27411448-1	2016	Because it plays an essential role in nitrogen (N) assimilation and photorespiration, the glutamine synthetase (GS)/glutamate synthase (GOGAT) system is widely accepted as occupying a central position in leaf N metabolism.	Nitrogen	38-46	glutamate synthase 1	Arabidopsis thaliana	116-134
30023219-6	2016	The G-CSF group exhibited protection against renal injury manifested by reducing blood urea nitrogen and serum-creatinine levels, improving histological architecture, and increasing the proliferative capacity of renal tubules.	Nitrogen	92-100	colony stimulating factor 3	Rattus norvegicus	4-9
27061370-1	2016	TaNAM transcription factors play an important role in controlling senescence, which in turn, influences the delivery of nitrogen, iron and other elements to the grain of wheat (Triticum aestivum) plants, thus contributing to grain nutritional value.	Nitrogen	120-128	NAC domain-containing protein 20	Triticum aestivum	0-5
27113132-2	2016	In Arabidopsis plant, the ubiquitin ligase ATL31 controls 14-3-3 stability via both direct interaction and ubiquitination, and this consequently regulates post-germinative growth in response to carbon and nitrogen nutrient availability.	Nitrogen	205-213	carbon/nitrogen insensitive 1	Arabidopsis thaliana	43-48
27258989-9	2016	Reaction of 2 (iPr) Cl with azobenzene led to N-N bond scission giving 6 (iPr) Cl, in which one of the NPh-fragments is coupled with the carbazole nitrogen to form a central eta(2) -bonded hydrazide(-1), whereas the other NPh-fragment binds to zirconium acting as an imido-ligand.	Nitrogen	147-155	DNA polymerase iota	Homo sapiens	174-180
27314333-11	2016	Our findings provide evidence for the critical role of N-glycosylation in the biogenesis of Rspo1.	Nitrogen	55-56	R-spondin 1	Homo sapiens	92-97
27145370-4	2016	In diabetic rats, CDK5 inhibitor roscovitine decreased renal fibrosis and improved renal function as demonstrated by a decrease in levels of blood urine nitrogen (BUN), serum creatinine and beta2-microglobulin.	Nitrogen	153-161	cyclin-dependent kinase 5	Rattus norvegicus	18-22
27121589-9	2016	These results indicate that N2 gas in Ar-CAP modifies the ratio of ROS to RNS, and suppresses the apoptosis induced by Ar-CAP.	Nitrogen	28-30	DDB1 and CUL4 associated factor 6	Homo sapiens	38-44
27121589-9	2016	These results indicate that N2 gas in Ar-CAP modifies the ratio of ROS to RNS, and suppresses the apoptosis induced by Ar-CAP.	Nitrogen	28-30	DDB1 and CUL4 associated factor 6	Homo sapiens	119-125
27258319-0	2016	Reconfiguration of N Metabolism upon Hypoxia Stress and Recovery: Roles of Alanine Aminotransferase (AlaAT) and Glutamate Dehydrogenase (GDH).	Nitrogen	19-20	glutamic--pyruvic transaminase	Homo sapiens	101-106
19432497-1	2009	Clodronic acid (Cl(2)-MBP [dichloromethylene bisphosphonic acid], clodronate) is a halogenated non-nitrogen-containing bisphosphonate with antiresorptive efficacy in a variety of diseases associated with excessive bone resorption.	Nitrogen	99-107	myelin basic protein	Homo sapiens	22-25
27050503-6	2016	SDS-PAGE and Western blot analysis showed that the glycosylated precursor recombinant hGAA had a molecular mass of 110kDa due to the presence of seven N-glycosylation sites.	Nitrogen	151-152	alpha glucosidase	Homo sapiens	86-90
18992821-4	2009	The "domain" architecture of trout CD18 and CD11b-like subunits retains several characteristics of the mammalian ortholog proteins, such as cysteine-rich regions, N-linked glycosylation sites and several proposed domains and signal sequences (von Willebrand factor type A, Integrin alpha, Integrin B tail, EGF, and Transmembrane domain).	Nitrogen	163-164	CD18 protein	Oncorhynchus mykiss	35-39
18992821-4	2009	The "domain" architecture of trout CD18 and CD11b-like subunits retains several characteristics of the mammalian ortholog proteins, such as cysteine-rich regions, N-linked glycosylation sites and several proposed domains and signal sequences (von Willebrand factor type A, Integrin alpha, Integrin B tail, EGF, and Transmembrane domain).	Nitrogen	163-164	alpha M integrin	Oncorhynchus mykiss	44-49
19858116-6	2009	Total nutrient accumulation was similar between lines, but grain Fe, Zn, and N were at lower concentrations in the NAM knockdown line.	Nitrogen	77-78	NAC domain-containing protein 20	Triticum aestivum	115-118
27195597-3	2016	We found that an increase of 10 mug/m(3) in particulate matter with an aerodynamic diameter of 10 mum or less (PM10), sulfur dioxide (SO2) and nitrogen dioxide (NO2) was associated with a 1.58% (95% confidence interval (CI): 0.12-3.06%), 3.45% (95% CI: 1.30-5.66%) and 2.35% (95% CI: 0.42-4.32%) increase of COPD mortality over a lag of 0-15 days, respectively.	Nitrogen	143-151	COPD	Homo sapiens	308-312
22291549-3	2009	The specific surface area (SSA(BET)) of the nanoparticles was measured by nitrogen adsorption (BET analysis).	Nitrogen	74-82	delta/notch like EGF repeat containing	Homo sapiens	31-34
27071465-1	2016	By employing dopamine as a nitrogen source and reducing agent, the block copolymer P123 as a pore forming agent, and graphene oxide as a carbon precursor, we present, for the first time, a convenient and controllable approach to the preparation of a novel uniformly nitrogen doped porous graphene (N-PGR) material.	Nitrogen	266-274	progesterone receptor	Homo sapiens	300-303
19182340-2	2009	A very interesting characteristics was found for the extremely shallow SSF, in which a high nitrogen removal efficiency was obtained despite the effective hydraulic retention time was only 1/8 times as long as the standard SSF.	Nitrogen	92-100	peter pan homolog	Homo sapiens	71-74
19182340-2	2009	A very interesting characteristics was found for the extremely shallow SSF, in which a high nitrogen removal efficiency was obtained despite the effective hydraulic retention time was only 1/8 times as long as the standard SSF.	Nitrogen	92-100	peter pan homolog	Homo sapiens	223-226
19182340-3	2009	The results of kinetic analysis confirmed that the high volumetric nitrogen removal efficiency observed in the extremely shallow SSF did not depend on high response against the water temperature but on much higher basic nitrogen removal activity compared with other SSF.	Nitrogen	67-75	peter pan homolog	Homo sapiens	129-132
27071465-2	2016	Using the prepared N-PGR as the supporting material, a novel nitrogen doped porous graphene/Pt nanoflower material (Pt/N-PGR) was obtained by a green and simple method.	Nitrogen	61-69	progesterone receptor	Homo sapiens	21-24
19182340-3	2009	The results of kinetic analysis confirmed that the high volumetric nitrogen removal efficiency observed in the extremely shallow SSF did not depend on high response against the water temperature but on much higher basic nitrogen removal activity compared with other SSF.	Nitrogen	67-75	peter pan homolog	Homo sapiens	266-269
19182340-3	2009	The results of kinetic analysis confirmed that the high volumetric nitrogen removal efficiency observed in the extremely shallow SSF did not depend on high response against the water temperature but on much higher basic nitrogen removal activity compared with other SSF.	Nitrogen	220-228	peter pan homolog	Homo sapiens	129-132
27071465-2	2016	Using the prepared N-PGR as the supporting material, a novel nitrogen doped porous graphene/Pt nanoflower material (Pt/N-PGR) was obtained by a green and simple method.	Nitrogen	61-69	progesterone receptor	Homo sapiens	121-124
19182340-5	2009	Results of morphological analysis of rhizosphere collected from respective reed-bed suggested that the extremely shallow SSF lead to a very high-density rhizosphere, resulting in a high basic nitrogen removal activity and volumetric phosphorus removal efficiency.	Nitrogen	192-200	peter pan homolog	Homo sapiens	121-124
26634234-5	2016	The X-ray structures of E-1a, E-1b and E-1c show a slightly shortened N-C bond to the alkene moieties.	Nitrogen	70-71	branched chain keto acid dehydrogenase E1 subunit beta	Homo sapiens	30-34
19052235-2	2008	Here, we present a 4-step method to fully reconstruct the leucine-responsive protein (Lrp) regulon in Escherichia coli K-12 MG 1655 that regulates nitrogen metabolism.	Nitrogen	147-155	DNA-binding transcriptional dual regulator Lrp	Escherichia coli str. K-12 substr. MG1655	58-84
19052235-2	2008	Here, we present a 4-step method to fully reconstruct the leucine-responsive protein (Lrp) regulon in Escherichia coli K-12 MG 1655 that regulates nitrogen metabolism.	Nitrogen	147-155	DNA-binding transcriptional dual regulator Lrp	Escherichia coli str. K-12 substr. MG1655	86-89
16958619-4	2007	(15)N-HSQC (heteronuclear single-quantum correlation) studies with mPrP (mouse PrP)-(23-231) show that a total of 150 dispersed amide signals are resolved in the native form, whereas only 65 amide signals with little chemical shift dispersion are observable in the pH 4 form.	Nitrogen	4-5	prion protein	Mus musculus	68-71
17160169-3	2007	In the cases where eta2,eta2-dinitrogen compounds were isolated, both structural and computational data have established significant imido character in the metal-nitrogen bonds.	Nitrogen	31-39	DNA polymerase iota	Homo sapiens	19-23
17160169-3	2007	In the cases where eta2,eta2-dinitrogen compounds were isolated, both structural and computational data have established significant imido character in the metal-nitrogen bonds.	Nitrogen	31-39	DNA polymerase iota	Homo sapiens	24-28
17269927-2	2007	Insights into the structure and function of the envelope (Env) protein of HIV-1 suggest that the virus is under strong selection pressure by the immune response leading to constant mutations in the Env protein including the N-glycosylation sites.	Nitrogen	224-225	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	48-56
17269927-2	2007	Insights into the structure and function of the envelope (Env) protein of HIV-1 suggest that the virus is under strong selection pressure by the immune response leading to constant mutations in the Env protein including the N-glycosylation sites.	Nitrogen	224-225	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	58-61
17269927-2	2007	Insights into the structure and function of the envelope (Env) protein of HIV-1 suggest that the virus is under strong selection pressure by the immune response leading to constant mutations in the Env protein including the N-glycosylation sites.	Nitrogen	224-225	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	198-201
18759743-8	2008	Our data favour a model in which (1) the role of Sch9 in the general stress response switches depending on TORC1 activity and (2) Sch9 and TORC1 have independent and additive effects on genes induced upon nitrogen and amino acid starvation.	Nitrogen	205-213	CREB regulated transcription coactivator 1	Homo sapiens	107-112
18759743-8	2008	Our data favour a model in which (1) the role of Sch9 in the general stress response switches depending on TORC1 activity and (2) Sch9 and TORC1 have independent and additive effects on genes induced upon nitrogen and amino acid starvation.	Nitrogen	205-213	CREB regulated transcription coactivator 1	Homo sapiens	139-144
27073020-0	2016	DNA hypomethylation upregulates expression of the MGAT3 gene in HepG2 cells and leads to changes in N-glycosylation of secreted glycoproteins.	Nitrogen	1-2	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	50-55
18484638-0	2008	The structure and chemical bonding in the N(2)-CuX and N(2)...XCu (X = F, Cl, Br) systems studied by means of the molecular orbital and Quantum Chemical Topology methods.	Nitrogen	42-46	cut like homeobox 1	Homo sapiens	47-50
17115277-3	2007	A key uTi, bikunin, is attached to O-linked and N-linked glycoconjugates.	Nitrogen	48-49	alpha-1-microglobulin/bikunin precursor	Homo sapiens	6-9
17115277-3	2007	A key uTi, bikunin, is attached to O-linked and N-linked glycoconjugates.	Nitrogen	48-49	alpha-1-microglobulin/bikunin precursor	Homo sapiens	11-18
18834188-5	2008	Although most of our analogues showed good to excellent affinities at both targets, specific features such as cyclobutyl substitution on the basic nitrogen and stereochemistry at the 3-position of the chroman moiety seemed necessary for antagonism at the 5-HT 1A receptor.	Nitrogen	147-155	5-hydroxytryptamine receptor 1A	Rattus norvegicus	255-262
26654979-10	2016	Among the peptides/proteins identified, ACSL, ACOX2, MTP, and THIKB contribute to regulation of fatty acid metabolism and ARG1, ARLY, and OAT, which regulate nitrogen and ammonia metabolism having direct relevance to ethanol-induced liver injury.	Nitrogen	158-166	arginase, liver	Mus musculus	122-126
18768757-3	2008	The decay kinetics of GAL1p-driven mRNAs revealed a dose-dependent mRNA stabilization upon UV-irradiation that was not observed after heat or saline shocks, or during nitrogen starvation.	Nitrogen	167-175	galactokinase	Saccharomyces cerevisiae S288C	22-27
28773378-2	2016	The used phosphoric acid:date pit ratio dictated the characteristics of the prepared ACs; the equivalent BET-nitrogen surface area varied from 794 m2/g for a ratio of 5:1, to 1707 m2/g for a ratio of 2:1, whereas the micropore volume changed in value from 0.24 cm3/g for the 5:1 ratio to 0.59 cm3/g for the 2:1 ratio.	Nitrogen	109-117	delta/notch like EGF repeat containing	Homo sapiens	105-108
18703016-3	2008	We report that the majority of human TRPV5 exogenously expressed in the Xenopus oocyte plasma membrane was complexly N-glycosylated whereas that for human TRPV6 was core-glycosylated.	Nitrogen	117-118	transient receptor potential cation channel subfamily V member 5	Homo sapiens	37-42
27220433-9	2016	2 Compared with NS group, the cerebral AQP4 and COX-2 mRNA and protein expression at each time point in H2S group after exposure were significantly increased (P&lt;0.01).	Nitrogen	16-18	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	48-53
21580958-1	2008	In the title compound, C(25)H(34)O(4), one n-hexyl chain of the hex-yloxy group adopts a fully extended all-trans conformation, and the other n-hexyl chain displays disorder with site occupancies of 0.470 (3) and 0.530 (3).	Nitrogen	1-2	hematopoietically expressed homeobox	Homo sapiens	45-48
26890684-2	2016	In this study, we found an efficient strategy to prepare nitrogen, phosphorus, and sulfur co-doped hollow carbon shells (denote as NPS-HCS) with a surface area of 1020 m(2)  g(-1).	Nitrogen	57-65	holocarboxylase synthetase	Homo sapiens	135-138
18767802-1	2008	This paper expands on the scope and utility of the temporary conversion of N-acetyl groups to alkyl imidates when attempting to glycosylate at O-4 of N-acetylglucosamine acceptors.	Nitrogen	75-76	immunoglobulin kappa variable 1D-37 (non-functional)	Homo sapiens	143-146
18710804-0	2008	Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4.	Nitrogen	61-69	immunoglobulin kappa variable 1D-27 (pseudogene)	Homo sapiens	134-137
27005614-6	2016	For example, cytosolic glutamine synthetase (GS1), heat shock protein 70 (Hsp70), and chloroplastic elongation factor G (cpEF-G) were involved in pigment-related nitrogen synthesis as well as protein synthesis and processing.	Nitrogen	162-170	pseudouridine 5'-phosphatase	Homo sapiens	45-48
18525017-9	2008	In separate studies, the action of central N/OFQ to decrease plasma AVP levels in naive water-restricted rats was differentially altered by intracerebroventricular Galphaz ODN (blunted) and Galphaq ODN (augmented) pretreatment.	Nitrogen	43-44	G protein subunit alpha q	Rattus norvegicus	190-197
26989612-15	2016	The importance of nitrogen and iodine recycling in sheep was highlighted by the highly preferential expression of SLC14A1-urea (rumen), RHBG-ammonia (intestines) and SLC5A5-iodine (abomasum).	Nitrogen	18-26	urea transporter 1	Ovis aries	114-121
18639462-2	2008	The results showed that C-8 nitrogen-containing baicalein analogues 3a-3f exhibited potent CDK1/Cyclin B inhibitory activities.	Nitrogen	28-36	homeobox C8	Homo sapiens	24-27
26898953-6	2016	Analysis on highly expressed alleles on each background suggested ASN1 as a candidate transcript underlying nitrogen consumption differences between two strains.	Nitrogen	108-116	asparagine synthase (glutamine-hydrolyzing) 1	Saccharomyces cerevisiae S288C	66-70
18524852-0	2008	Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation.	Nitrogen	129-130	malectin	Homo sapiens	0-8
26899143-0	2016	The modification of Gat1p in nitrogen catabolite repression to enhance non-preferred nitrogen utilization in Saccharomyces cerevisiae.	Nitrogen	29-37	Gat1p	Saccharomyces cerevisiae S288C	20-25
18507803-0	2008	The lack of alternative oxidase at low temperature leads to a disruption of the balance in carbon and nitrogen metabolism, and to an up-regulation of antioxidant defence systems in Arabidopsis thaliana leaves.	Nitrogen	102-110	alternative oxidase 2	Arabidopsis thaliana	12-31
18507803-9	2008	Starch content and a ratio of carbon to nitrogen were higher in aox1a than in WT.	Nitrogen	40-48	alternative oxidase 1A	Arabidopsis thaliana	64-69
18507803-10	2008	Our results indicate that a lack of AOX was linked to a difference in the carbon and nitrogen balance, and an up-regulation of the transcription of antioxidant defence system at low temperature.	Nitrogen	85-93	alternative oxidase 2	Arabidopsis thaliana	36-39
18591743-7	2008	(vi) alpha-Kl in urine increases TRPV5 channel abundance at the luminal cell surface by hydrolyzing the N-linked extracellular sugar residues of TRPV5, resulting in increased Ca(2+) influx from the lumen.	Nitrogen	104-105	transient receptor potential cation channel, subfamily V, member 5	Mus musculus	33-38
18591743-7	2008	(vi) alpha-Kl in urine increases TRPV5 channel abundance at the luminal cell surface by hydrolyzing the N-linked extracellular sugar residues of TRPV5, resulting in increased Ca(2+) influx from the lumen.	Nitrogen	104-105	transient receptor potential cation channel, subfamily V, member 5	Mus musculus	145-150
26899143-0	2016	The modification of Gat1p in nitrogen catabolite repression to enhance non-preferred nitrogen utilization in Saccharomyces cerevisiae.	Nitrogen	85-93	Gat1p	Saccharomyces cerevisiae S288C	20-25
26899143-3	2016	Among these regulators, two positive regulators (Gln3p and Gat1p) could be phosphorylated and sequestered in the cytoplasm leading to the transcription of non-preferred nitrogen metabolic genes being repressed.	Nitrogen	169-177	Gat1p	Saccharomyces cerevisiae S288C	59-64
18479955-1	2008	Ribophorin I, a 67 kDa subunit of the oligosaccharyl transferase complex, is involved in facilitating N-linked glycosylation of polypeptides.	Nitrogen	102-103	ribophorin I	Homo sapiens	0-12
26899143-7	2016	In addition, the modifications of Gat1p (mutations on the NLS and truncation on the NLRS) were attempted to enhance the transcription of non-preferred nitrogen metabolic genes.	Nitrogen	151-159	Gat1p	Saccharomyces cerevisiae S288C	34-39
26899143-10	2016	Based on these results, the genetic engineering on Gat1p has a great potential in enhancing non-preferred nitrogen metabolism in S. cerevisiae.	Nitrogen	106-114	Gat1p	Saccharomyces cerevisiae S288C	51-56
26732532-3	2016	Those efforts produced compound 17 {N-(trans-4-aminomethylcyclohexanecarbonyl)-l-Tyr[O-(quinolin-2-yl)methyl]-NH-octyl} [IC50=0.22 and 77muM for Plm and urokinase (UK), respectively], which showed not only 2.4-fold greater Plm inhibition than YO-2, but also an improvement in selectivity (Plm/UK) by 35-fold.	Nitrogen	36-37	plasminogen	Homo sapiens	145-148
18381078-0	2008	Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme.	Nitrogen	19-20	ADAM metallopeptidase domain 10	Homo sapiens	40-46
18381078-1	2008	A disintegrin and metalloprotease 10 (ADAM10) is a type I transmembrane glycoprotein with four potential N-glycosylation sites (N267, N278, N439 and N551), that cleaves several plasma membrane proteins.	Nitrogen	105-106	ADAM metallopeptidase domain 10	Homo sapiens	0-36
18381078-1	2008	A disintegrin and metalloprotease 10 (ADAM10) is a type I transmembrane glycoprotein with four potential N-glycosylation sites (N267, N278, N439 and N551), that cleaves several plasma membrane proteins.	Nitrogen	105-106	ADAM metallopeptidase domain 10	Homo sapiens	38-44
18381078-10	2008	In conclusion, N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.	Nitrogen	15-16	ADAM metallopeptidase domain 10	Homo sapiens	46-52
26732532-3	2016	Those efforts produced compound 17 {N-(trans-4-aminomethylcyclohexanecarbonyl)-l-Tyr[O-(quinolin-2-yl)methyl]-NH-octyl} [IC50=0.22 and 77muM for Plm and urokinase (UK), respectively], which showed not only 2.4-fold greater Plm inhibition than YO-2, but also an improvement in selectivity (Plm/UK) by 35-fold.	Nitrogen	36-37	plasminogen	Homo sapiens	223-226
26732532-3	2016	Those efforts produced compound 17 {N-(trans-4-aminomethylcyclohexanecarbonyl)-l-Tyr[O-(quinolin-2-yl)methyl]-NH-octyl} [IC50=0.22 and 77muM for Plm and urokinase (UK), respectively], which showed not only 2.4-fold greater Plm inhibition than YO-2, but also an improvement in selectivity (Plm/UK) by 35-fold.	Nitrogen	36-37	plasminogen	Homo sapiens	223-226
26824618-6	2016	Furthermore, nitrogen-doped carbon microspheres are prepared by the direct carbonization of these polymer microspheres, which exhibit microporous BET surface areas of 400-500 m(2) g(-1), high nitrogen contents of 5-6 wt %, and a good CO2 adsorption capacity up to 3.6 mmol g(-1) at 0  C. KOH activation is further employed to develop the porous texture of carbon microspheres without sacrificing the spherical morphology.	Nitrogen	13-21	delta/notch like EGF repeat containing	Homo sapiens	146-149
18505360-9	2008	However, this may turn out to be a double-edged sword, since the inhibition of O-methylation with the COMT inhibitor may hypothetically contribute to increased N-methylation.	Nitrogen	160-161	catechol-O-methyltransferase	Homo sapiens	102-106
26528537-0	2016	Physiological Effects of GLT1 Modulation in Saccharomyces cerevisiae Strains Growing on Different Nitrogen Sources.	Nitrogen	98-106	glutamate synthase (NADH)	Saccharomyces cerevisiae S288C	25-29
18332087-10	2008	The stimulatory activity was dependent partly on N-linked glycosylation of hZP3.	Nitrogen	49-50	zona pellucida glycoprotein 3	Homo sapiens	75-79
18186042-7	2008	Both endogenous and overexpressed forms of FGFR4 exhibited N-glycosylation.	Nitrogen	59-60	fibroblast growth factor receptor 4	Mus musculus	43-48
18340083-3	2008	Here, we show that mouse GPIHBP1 is N-glycosylated at Asn-76 within the Ly-6 domain.	Nitrogen	36-37	GPI-anchored HDL-binding protein 1	Mus musculus	25-32
18340083-7	2008	Mutating the N-glycosylation site in mouse GPIHBP1 results in an accumulation of GPIHBP1 in the endoplasmic reticulum and a markedly reduced amount of the protein on the cell surface.	Nitrogen	13-14	GPI-anchored HDL-binding protein 1	Mus musculus	43-50
18340083-7	2008	Mutating the N-glycosylation site in mouse GPIHBP1 results in an accumulation of GPIHBP1 in the endoplasmic reticulum and a markedly reduced amount of the protein on the cell surface.	Nitrogen	13-14	GPI-anchored HDL-binding protein 1	Mus musculus	81-88
18340083-9	2008	Eliminating the N-glycosylation site in a truncated soluble version of GPIHBP1 causes a modest reduction in the secretion of the protein.	Nitrogen	16-17	GPI-anchored HDL-binding protein 1	Mus musculus	71-78
18340083-10	2008	These studies demonstrate that N-glycosylation of GPIHBP1 is important for the trafficking of GPIHBP1 to the cell surface.	Nitrogen	31-32	GPI-anchored HDL-binding protein 1	Mus musculus	50-57
18340083-10	2008	These studies demonstrate that N-glycosylation of GPIHBP1 is important for the trafficking of GPIHBP1 to the cell surface.	Nitrogen	31-32	GPI-anchored HDL-binding protein 1	Mus musculus	94-101
18325729-0	2008	Preclinical evidence for nitrogen-containing bisphosphonate inhibition of farnesyl diphosphate (FPP) synthase in the kidney: implications for renal safety.	Nitrogen	25-33	farnesyl diphosphate synthase	Rattus norvegicus	74-109
18325729-3	2008	Nitrogen-containing bisphosphonates directly inhibit farnesyl diphosphate (FPP) synthase activity (mevalonate pathway) and reduce protein prenylation leading to osteoclast cell death.	Nitrogen	0-8	farnesyl diphosphate synthase	Rattus norvegicus	53-88
18343219-0	2008	Thr but Asn of the N-glycosylation sites of PrP is indispensable for its misfolding.	Nitrogen	19-20	prion protein	Mus musculus	44-47
18343219-1	2008	Prion protein (PrP) contains two N-linked glycosylation sites.	Nitrogen	33-34	prion protein	Mus musculus	0-13
18343219-1	2008	Prion protein (PrP) contains two N-linked glycosylation sites.	Nitrogen	33-34	prion protein	Mus musculus	15-18
18343219-3	2008	To define the influence of amino acid substitution at the N-linked glycosylation sites on the conversion efficiency of mouse PrP, we tested each of all 19 amino acid substitutions at either one of the N-linked glycosylation sites (codon 180, 182, 196 or 198).	Nitrogen	58-59	prion protein	Mus musculus	125-128
18343219-5	2008	The majority of mutant PrP with substitutions at the Asn residues of the N-linked glycosylation sites were conversion-competent, whereas most mutant PrP with substitutions at the Thr residues were conversion-incompetent.	Nitrogen	73-74	prion protein	Mus musculus	23-26
18399632-2	2008	X-ray diffraction and NMR spectroscopy establish that the resulting dimeric dinitrogen compounds contain an unusual mu2,eta(2)-bridging indenyl ring and a weakly activated N2 ligand.	Nitrogen	76-86	endothelin receptor type A	Homo sapiens	120-123
18399632-4	2008	Compounds bearing two [(i)Pr] or three methyl substituents are stable as eta(9) sandwich compounds for weeks under dinitrogen likely due to the inability to dimerize through a two-atom N2 bridge.	Nitrogen	115-125	endothelin receptor type A	Homo sapiens	73-76
18363419-7	2008	The nitrogen gas adsorption on the surface of core-shell nanostructures was determined by BET surface area analysis.	Nitrogen	4-12	delta/notch like EGF repeat containing	Homo sapiens	90-93
18452889-8	2008	TUSC3 is thought to encode a subunit of the endoplasmic reticulum-bound oligosaccharyltransferase complex that catalyzes a pivotal step in the protein N-glycosylation process.	Nitrogen	151-152	tumor suppressor candidate 3	Homo sapiens	0-5
18288574-8	2008	During leaf senescence the cytosolic isozymes, GS1 and GSr, were the predominant forms, suggesting major roles in assimilating ammonia during the critical phases of remobilisation of nitrogen to the grain.	Nitrogen	183-191	glutathione synthetase, chloroplastic	Triticum aestivum	47-50
18341291-1	2008	The role of N-linked glycosylation of beta-subunits in the functional properties of the oligomeric P-type ATPases Na,K- and H,K-ATPase has been examined by expressing glycosylation-deficient Asn-to-Gln beta-variants in Xenopus oocytes.	Nitrogen	12-13	ATPase Na+/K+ transporting subunit alpha 1 L homeolog	Xenopus laevis	99-134
18375764-3	2008	CyaA utilizes a heavily N-glycosylated beta(2) integrin receptor CD11b/CD18 (alpha(M)beta(2), Mac-1, or CR3).	Nitrogen	24-25	teratocarcinoma-derived growth factor 1 pseudogene 3	Homo sapiens	104-107
18302414-2	2008	This method employs molecular iodine to mediate the cyclization from the 5"-Omicron-hydroxyl group of the sugar ring and C-6 at the position of the nitrogen base in ammonia water under mild conditions without any other aprotic organic solvent.	Nitrogen	148-156	complement C6	Homo sapiens	121-124
18292673-7	2008	METHODS: N-demethylation of racemic methadone and individual enantiomers by expressed CYPs 2B6, 2C19, and 3A4 was evaluated.	Nitrogen	9-10	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	86-100
17980859-6	2008	Kinetic and inhibition studies indicated that the side-chain N-dealkylation is mediated by CYP2C11 and CYP3A2, whereas the aromatic ring O-demethylation is mediated by CYP2D2 and CYP2C6 in untreated male rats.	Nitrogen	61-62	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	103-109
18239274-2	2008	Ionizing irradiation is known to cause genotoxic damage through the generation of reactive oxygen species (ROS) and nitrogen species (RNS) and we have found that a signaling pathway for the nuclear translocation of Translin is initiated in association and efficiently blocked by a specific inhibitor of nitric oxide synthase (NOS).	Nitrogen	116-124	translin	Mus musculus	215-223
18239274-2	2008	Ionizing irradiation is known to cause genotoxic damage through the generation of reactive oxygen species (ROS) and nitrogen species (RNS) and we have found that a signaling pathway for the nuclear translocation of Translin is initiated in association and efficiently blocked by a specific inhibitor of nitric oxide synthase (NOS).	Nitrogen	116-124	nitric oxide synthase 1, neuronal	Mus musculus	303-324
18479025-1	2008	Nitrogen-doped nanosize TiO2 was prepared by sol-gel method with TBT and EDA as forerunner body, ethanol as solvent and glacial acetic acid as inhibitor.	Nitrogen	0-8	ectodysplasin A	Homo sapiens	73-76
18005950-5	2008	Nine out of 12 enzymes represented variably N-glycosylated proteins carrying common (Hex)(0-4)(HexNAc)(0-6)+(Man)(3)(GlcNAc)(2) structures, most of them being hybrid/complex glycans.	Nitrogen	0-1	hematopoietically expressed homeobox	Homo sapiens	85-88
18466090-5	2008	One recently described family of (UUAGGG)n-containing subterminal RNAs appears to be critical for telomere integrity; these RNAs associate with telomeric chromatin and are regulated by RNA surveillance factors including human homologs of the yeast Est1p protein.	Nitrogen	1-2	Est1p	Saccharomyces cerevisiae S288C	248-253
18833553-3	2008	Elongation of its C-6 position towards a bicyclic sugar amino acid and conversion into a suitable glycosyl donor enabled efficient N-glycosylation with 2-aminopurine to take place to afford the nucleosidic part of miharamycin B.	Nitrogen	131-132	complement C6	Homo sapiens	18-21
17297804-3	2007	Speakers" average vowel duration and SPL generally rose with increasing N/S.	Nitrogen	72-73	sphingosine-1-phosphate lyase 1	Homo sapiens	37-40
17546979-3	2007	The results demonstrated that at a total nitrogen (TN) loading of 18 mg/L.h, a TN removal efficiency in keeping with and even exceeding the theoretical maximum efficiency based on the level of internal recycle, was possible and a nitrification rate of 15 mg/L.h was sustained with a HRT of only 2.5 h at 15 degrees C. Furthermore, soluble COD and BOD5 in the effluent of the pilot plant were reduced to levels well below most regulatory discharge limits.	Nitrogen	41-49	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	339-342
17115712-7	2006	In contrast, the FXa-catalyzed hydrolysis of N-alpha-Z-D-Arg-Gly-Arg-pNA.2HCl (S-2765) and H-D-Ile-L-Pro-L-Arg-pNA.HCl (S-2288) is most consistent with two-proton bridges forming at the transition state between Ser195 OgammaH and His57 N(epsilon)2 and His57 Ndelta1 and Asp102 COObeta- at the active site, with transition-state fractionation factors of phi1 = phi2 = 0.57 +/- 0.07 and phiS = 0.78 +/- 0.16 for solvent rearrangement for S-2765 and phi1 = phi2 = 0.674 +/- 0.001 for S-2288 under enzyme saturation with the substrate at pH 8.40 and 25.0 +/- 0.1 degrees C. The rate-determining step(s) in these reactions is most likely the cleavage of the C-N bond and departure of the leaving group.	Nitrogen	45-46	protein phosphatase 1 regulatory inhibitor subunit 14B	Homo sapiens	353-357
17115712-7	2006	In contrast, the FXa-catalyzed hydrolysis of N-alpha-Z-D-Arg-Gly-Arg-pNA.2HCl (S-2765) and H-D-Ile-L-Pro-L-Arg-pNA.HCl (S-2288) is most consistent with two-proton bridges forming at the transition state between Ser195 OgammaH and His57 N(epsilon)2 and His57 Ndelta1 and Asp102 COObeta- at the active site, with transition-state fractionation factors of phi1 = phi2 = 0.57 +/- 0.07 and phiS = 0.78 +/- 0.16 for solvent rearrangement for S-2765 and phi1 = phi2 = 0.674 +/- 0.001 for S-2288 under enzyme saturation with the substrate at pH 8.40 and 25.0 +/- 0.1 degrees C. The rate-determining step(s) in these reactions is most likely the cleavage of the C-N bond and departure of the leaving group.	Nitrogen	45-46	protein phosphatase 1 regulatory inhibitor subunit 14B	Homo sapiens	447-451
16953504-6	2006	The important vulcanization accelerator mercaptobenzothiazole (C(7)H(5)NS(2), MBT) containing several donor sites reacts with the Zn(4)O(4) cluster with proton transfer from the NH group to one of the oxygen atoms of ZnO, and in addition the exocyclic thiono sulfur atom and the nitrogen atom coordinate to one and the same zinc atom, resulting in a binding energy of -247 kJ mol(-1).	Nitrogen	279-287	proteinase 3	Homo sapiens	78-81
17080401-6	2006	This study was conducted to optimize the incubation conditions of 4-ABP N-glucuronidation.	Nitrogen	72-73	amine oxidase copper containing 1	Homo sapiens	68-71
17252827-4	2006	The thermal stability showed up to about 300 degrees C under nitrogen flow, which was measured by TGA.	Nitrogen	61-69	T-box transcription factor 1	Homo sapiens	98-101
17026539-2	2006	After pre-culturing under nitrogen-deficiency conditions, we quantified the influx of (15)N-labeled ammonium in T-DNA insertion lines and observed that the loss of either AMT1;1 or AMT1;3 led to a decrease in the high-affinity ammonium influx of approximately 30%.	Nitrogen	26-34	ammonium transporter 1;1	Arabidopsis thaliana	171-177
17026539-2	2006	After pre-culturing under nitrogen-deficiency conditions, we quantified the influx of (15)N-labeled ammonium in T-DNA insertion lines and observed that the loss of either AMT1;1 or AMT1;3 led to a decrease in the high-affinity ammonium influx of approximately 30%.	Nitrogen	26-34	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	171-175
16905358-5	2006	One gene, Nar1.2, was strongly carbon-regulated independently of Nit2; two genes, Nar1.1 and Nar1.6, were regulated by nitrogen and Nit2; and the other genes, Nar1.3, Nar1.4, and Nar1.5 were independent of Nit2 and responded to nitrogen or carbon treatments in a transient and not easily understandable way.	Nitrogen	119-127	uncharacterized protein	Chlamydomonas reinhardtii	93-99
16942027-4	2006	The same interactions were preserved in the adduct with hCA IX, but in addition, a hydrogen bond between the SH moiety of the inhibitor and the amide nitrogen of Gln67 was evidenced, which may explain the almost 2 times more effective inhibition of the tumor-associated isozyme over the cytosolic isoform.	Nitrogen	150-158	carbonic anhydrase 9	Homo sapiens	56-62
16933946-19	2006	A series of isotope-labeling experiments has been carried out, and the modes with the greatest metal-nitrogen stretching character have been assigned to peaks at approximately 960 and approximately 1300 cm(-1) in both the iron and cobalt [PhBP3]MNPh complexes.	Nitrogen	101-109	PHB1 pseudogene 3	Homo sapiens	239-244
16495211-10	2006	CLC intervention at 42 and 66 h after the priming dose resulted in marked progressive elevation of plasma blood urea nitrogen and creatinine resulting in ARF and death of mice.	Nitrogen	117-125	Charcot-Leyden crystal protein	Mus musculus	0-3
16858410-5	2006	The hABH3 structure reveals the beta-strand jelly-roll fold that coordinates a catalytically active iron centre by a conserved His1-X-Asp/Glu-X(n)-His2 motif.	Nitrogen	143-146	alkB homolog 3, alpha-ketoglutarate dependent dioxygenase	Homo sapiens	4-9
16813429-1	2006	The present paper deals with the synthesis and structural characterization of novel neutral oxorhenium(V) complexes of the general formula ReO[SNO][NN].	Nitrogen	148-150	strawberry notch homolog 1	Homo sapiens	143-146
16990950-4	2006	High survival after freezing was observed after dehydration with PVS2 for 20 min, cooling shoot tips placed in a droplet of PVS2 solution on aluminum foil strips by immersing the foil strips in liquid nitrogen, warming them by plunging the foil strips into a 0.8 M sucrose solution (at 40 degrees C) for 30 s and unloading in 0.8 M sucrose for 30 min.	Nitrogen	201-209	putative vetispiradiene synthase 3	Solanum tuberosum	124-128
16019130-5	2006	The inhibitory effect of AP-N mRNA expression was also observed in the cells treated with pravastatin and other nitrogen-containing bisphosphonates, which inhibit the key enzyme in the isoprenoid biosynthesis pathway.	Nitrogen	112-120	alanyl aminopeptidase, membrane	Homo sapiens	25-29
16749848-3	2006	In these compounds, LH2 refers to the tetraiminodiphenol macrocycle in the zwitterionic form whose two uncoordinated imine nitrogens are protonated and hydrogen-bonded to the metal-bound phenolate oxygens.	Nitrogen	123-132	LIM homeobox 2	Homo sapiens	20-23
16756300-8	2006	The His1 side chain nitrogen and backbone amides of the active site channel are shown to be less favorable transient proton locations, as compared to the Cys2 sulfur.	Nitrogen	20-28	viral integration site 1	Homo sapiens	4-8
16858123-3	2006	Of six cDNA-expressed rat P450 isoforms tested, CYP3A2 and CYP2C11 had high rates for N-debutlylation and 3"-hydroxylation of bupivacaine, respectively.	Nitrogen	9-10	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	48-54
25580068-0	2006	A 0.6 T/650 mm RT Bore Solid Nitrogen Cooled MgB2 Demonstration Coil for MRI-a Status Report.	Nitrogen	29-37	coilin	Homo sapiens	64-68
25580068-2	2006	The coil is to be maintained cold by solid nitrogen kept in the solid state by a cryocooler.	Nitrogen	43-51	coilin	Homo sapiens	4-8
16713428-7	2006	With UGT1A9, the production of metabolites 1 and 2 proceeded at a K(m) of 38+/-25 and 45+/-15 micromol/L, whereas the K(m) for retigabine N-glucuronidation by human liver microsomal fractions was 145+/-39 micromol/L.	Nitrogen	138-139	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	5-11
16490286-5	2006	Using enzymatic deglycosylation of clusterin isolated from cerebrospinal fluid, we found that the carbohydrates attached to clusterin were of the N-linked type and sialic acids.	Nitrogen	146-147	clusterin	Homo sapiens	35-44
16490286-5	2006	Using enzymatic deglycosylation of clusterin isolated from cerebrospinal fluid, we found that the carbohydrates attached to clusterin were of the N-linked type and sialic acids.	Nitrogen	146-147	clusterin	Homo sapiens	124-133
18173719-2	2008	The resulting water-soluble octadiazopyruvoyl PAMAM (8G.1 DAP, 1.3) was shown to undergo Wolff rearrangements upon photolysis in methanol at lambda &gt; 300 nm to yield the methyl esters of the ketenes formed from the loss of nitrogen.	Nitrogen	226-234	death associated protein	Homo sapiens	58-61
19275045-7	2008	The obtained results indicate that the examined factors (nitrogen and carbon availability) influence the CSH of Bacillus spp.	Nitrogen	57-65	histocompatibility minor 13	Homo sapiens	121-124
17959596-1	2007	The nifU and nifS genes encode the components of a cellular machinery dedicated to the assembly of [2Fe-2S] and [4Fe-4S] clusters required for growth under nitrogen-fixing conditions.	Nitrogen	156-164	NFS1 cysteine desulfurase	Homo sapiens	13-17
26595179-1	2016	This study aimed to evaluate the influence of COD/N ratio and carbon source on simultaneous nitrogen and carbon removal processes.	Nitrogen	92-100	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	46-49
17920266-2	2007	Compound 2 and its derivatives could be docked to the prostacyclin receptor in two ways depending on the position of the nitrogen atom within the heteroaromatic ring.	Nitrogen	121-129	prostaglandin I2 receptor	Homo sapiens	54-75
21727512-5	2006	The decrease in emission efficiency at high temperature is attributed to the activation of carriers from the GaN dot to the nitrogen vacancy (V(N)) state of the Al(0.11)Ga(0.89)N barrier layer.	Nitrogen	124-132	gigaxonin	Homo sapiens	109-112
26595179-6	2016	At lower COD/N ratios, NH4(+)-N oxidation efficiencies were higher than 90%.	Nitrogen	13-14	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	9-12
16442292-3	2006	Several of these nitrogen-modified CA4 derivatives (both amino and nitro) demonstrate significant inhibition of tubulin assembly as well as cytotoxicity and in vivo blood flow reduction.	Nitrogen	17-25	carbonic anhydrase 4	Mus musculus	35-38
17761779-0	2007	Characterization of N-glucuronidation of 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051): a new xanthine oxidoreductase inhibitor.	Nitrogen	20-21	xanthine dehydrogenase	Homo sapiens	124-147
26595179-6	2016	At lower COD/N ratios, NH4(+)-N oxidation efficiencies were higher than 90%.	Nitrogen	23-24	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	9-12
26384088-0	2016	Short Communication: The Distribution of Potential N-Linked Glycosylation Sites in Gp120 Differs Among Major HIV-1 Subtypes Circulating in China.	Nitrogen	51-52	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	83-88
17999052-2	2007	N-[3-(1H-Imidazol-4-yl)propyl)]guanidines and N (G)-acylated derivatives are more efficacious and potent agonists at fusion proteins of the guinea pig histamine H(2) receptor and the short splice variant of G(salpha), G(salphaS) (gpH(2)R-G(salphaS)) than at the human isoform (hH(2)R-G(salphaS)).	Nitrogen	0-1	histamine receptor H2	Homo sapiens	277-283
18260386-6	2007	The integral of I(SPB) is second-order linear to I, with a very second order coefficient, meaning that the main excited substance is N2.	Nitrogen	133-135	surfactant protein B	Homo sapiens	18-21
18330156-1	2007	Polymer grafting of polystyrene (PS) on nitrogen-doped multiwall carbon nanotubes (CNx) was successfully obtained by a "grafting from" technique.	Nitrogen	40-48	calnexin	Homo sapiens	83-86
16455802-12	2006	Additionally, conjugation at the nitrogens of the pyrazole ring represents a new structural moiety for UGT1A-mediated reactions.	Nitrogen	33-42	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	103-108
16734383-4	2006	INTRODUCTION: Nitrogen-containing bisphosphonates (N-BPs) are potent inhibitors of bone resorption that act by inhibiting farnesyl diphosphate synthase, thereby indirectly preventing the prenylation of Rho family GTPases that are required for the function and survival of bone-resorbing osteoclasts.	Nitrogen	14-22	farnesyl diphosphate synthetase	Mus musculus	122-151
16689758-2	2006	OBJECTIVES: We investigated the function of N-glycosylation in the variable region of the heavy chain of a human monoclonal antibody, mAb-LE2E9, that partially inhibits factor VIII (FVIII) activity during coagulation.	Nitrogen	44-45	coagulation factor VIII	Mus musculus	169-180
16689758-4	2006	A mutant antibody lacking the N-glycosylation site in the variable region of the heavy chain inhibited FVIII activity by up to 40%, while inhibition by the native antibody was 80%.	Nitrogen	30-31	coagulation factor VIII	Mus musculus	103-108
26537799-0	2016	N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.	Nitrogen	0-1	caudal type homeobox 1	Homo sapiens	119-140
16609766-9	2006	The reaction of 1 with AgPF6 in acetone afforded complex [Ru(eta6-cymene)(N,O,O)]PF6 (7, where N,O,O = 4-alcoxide-4-phenyl-4-(pyridin-2-yl)butan-2-one) from the C-C coupling of a deprotonated methyl group of the coordinated acetone and the C=O moiety of 2-bzpy ligand.	Nitrogen	74-75	sperm associated antigen 17	Homo sapiens	25-28
17672841-0	2007	AtDUR3 represents the major transporter for high-affinity urea transport across the plasma membrane of nitrogen-deficient Arabidopsis roots.	Nitrogen	103-111	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	0-6
26537799-0	2016	N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.	Nitrogen	0-1	caudal type homeobox 1	Homo sapiens	142-146
17537870-6	2007	These studies indicate a major role of CYP2C8 in the N-demethylation reaction, whereas CYP3A4 only made a minor contribution.	Nitrogen	53-54	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	39-45
27065222-2	2016	Glucose promotes SREBP-cleavage activating protein (SCAP)/SREBP complex trafficking from the ER to the Golgi and subsequent SREBP activation via N-glycosylation of SCAP.	Nitrogen	145-146	SREBF chaperone	Homo sapiens	17-50
17658854-0	2007	New synthetic routes to chain-extended selenium, sulfur, and nitrogen analogues of the naturally occurring glucosidase inhibitor salacinol and their inhibitory activities against recombinant human maltase glucoamylase.	Nitrogen	61-69	maltase-glucoamylase	Homo sapiens	197-217
17658854-7	2007	The two nitrogen compounds also inhibited MGA but were less active, with Ki values of 0.8 and 35 microM.	Nitrogen	8-16	maltase-glucoamylase	Homo sapiens	42-45
16491492-2	2006	The results show that under high vacuum conditions, molecular KN3, RbN3 and CsN3 are present as stable high-temperature vapour species, together with variable amounts of nitrogen gas and the corresponding metal atoms.	Nitrogen	170-178	casein kappa	Homo sapiens	76-80
16491492-5	2006	The most intense IR features for KN3, RbN3 and CsN3 isolated in nitrogen matrices lie at 2005, 2004.4 and 2002.2 cm(-1), respectively, and correspond to the N3 asymmetric stretch.	Nitrogen	64-72	casein kappa	Homo sapiens	47-51
27065222-2	2016	Glucose promotes SREBP-cleavage activating protein (SCAP)/SREBP complex trafficking from the ER to the Golgi and subsequent SREBP activation via N-glycosylation of SCAP.	Nitrogen	145-146	SREBF chaperone	Homo sapiens	52-56
27065222-2	2016	Glucose promotes SREBP-cleavage activating protein (SCAP)/SREBP complex trafficking from the ER to the Golgi and subsequent SREBP activation via N-glycosylation of SCAP.	Nitrogen	145-146	SREBF chaperone	Homo sapiens	164-168
26579622-5	2015	The Fe-derived N-CNTs exhibited the highest BET (~870 m(2) g(-1)) and electrochemically accessible (~450 m(2) g(-1)) surface areas and, more importantly, the highest concentration of nitrogen incorporated into the carbon planes.	Nitrogen	15-16	delta/notch like EGF repeat containing	Homo sapiens	44-47
16386315-4	2006	The Xenopus laevis MAP kinase phosphatase X17c gene and the Yeast nitrogen starvation-induced protein phosphatase Yvh1p gene were revealed to be highly homologous with Pyst2-L.	Nitrogen	66-74	dual specificity phosphatase 7	Homo sapiens	168-173
16472779-8	2006	In addition, both AtGLN1;1 and AtCRK3 could be induced by natural or artificially induced leaf senescence, implying that such interaction may be involved in the regulation of nitrogen remobilization during leaf senescence.	Nitrogen	175-183	CDPK-related kinase 3	Arabidopsis thaliana	31-37
17623277-0	2007	Proteomic analysis of N-glycosylation in mosquito dopachrome conversion enzyme.	Nitrogen	22-23	24-dehydrocholesterol reductase	Homo sapiens	50-78
17623277-5	2007	A mosquito DCE was purified and its monosaccharide composition, N-glycosylation site, and oligosaccharide structures were determined.	Nitrogen	64-65	24-dehydrocholesterol reductase	Homo sapiens	11-14
26607208-8	2015	Our results suggest that the activation of ORL1 receptors by N/OFQ can potentiate P2X3 receptors in primary cultures of neonatal trigeminal neurons, which may be a mechanism for the nociceptive role of N/OFQ in the modulation of craniofacial pain.	Nitrogen	61-62	opioid related nociceptin receptor 1	Rattus norvegicus	43-47
17331556-0	2007	The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity.	Nitrogen	12-13	C-X-C motif chemokine ligand 12	Homo sapiens	60-67
17383704-6	2007	Molecular cloning of APA from G. blomhoffi brevicaudus venom predicted that it was a type II integral membrane protein containing 958 amino acid residues with 17 potential N-linked glycosylation sites.	Nitrogen	172-173	glutamyl aminopeptidase	Homo sapiens	21-24
16482348-3	2006	Particular emphasis is put on the unprecedented N-N cleavage reaction of the functionalized, micro-eta1:eta2 coordinated dinitrogen ligand.	Nitrogen	121-131	DNA polymerase iota	Homo sapiens	93-108
26607208-8	2015	Our results suggest that the activation of ORL1 receptors by N/OFQ can potentiate P2X3 receptors in primary cultures of neonatal trigeminal neurons, which may be a mechanism for the nociceptive role of N/OFQ in the modulation of craniofacial pain.	Nitrogen	202-203	opioid related nociceptin receptor 1	Rattus norvegicus	43-47
26555173-2	2015	Here, we delineate a pathway in which EGFR signaling, by increasing glucose uptake, promotes N-glycosylation of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and consequent activation of SREBP-1, an ER-bound transcription factor with central roles in lipid metabolism.	Nitrogen	93-94	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	112-153
16465618-2	2006	Aminoacylase 1 (ACY1; EC 3.5.14) is the most abundant of the aminoacylases, a class of enzymes involved in hydrolysis of N-acetylated proteins.	Nitrogen	121-122	aminoacylase 1	Homo sapiens	0-14
16465618-2	2006	Aminoacylase 1 (ACY1; EC 3.5.14) is the most abundant of the aminoacylases, a class of enzymes involved in hydrolysis of N-acetylated proteins.	Nitrogen	121-122	aminoacylase 1	Homo sapiens	16-20
16465618-5	2006	Nuclear magnetic resonance spectroscopy analysis of urine samples detected a distinct pattern of N-acetylated metabolites, consistent with ACY1 dysfunction.	Nitrogen	0-1	aminoacylase 1	Homo sapiens	139-143
16487345-1	2006	Gln3 and Gat1/Nil1 are GATA-family transcription factors responsible for transcription of nitrogen-catabolic genes in Saccharomyces cerevisiae.	Nitrogen	90-98	Gat1p	Saccharomyces cerevisiae S288C	9-13
16487345-1	2006	Gln3 and Gat1/Nil1 are GATA-family transcription factors responsible for transcription of nitrogen-catabolic genes in Saccharomyces cerevisiae.	Nitrogen	90-98	Gat1p	Saccharomyces cerevisiae S288C	14-18
16487345-5	2006	Gat1 and Gln3 localization are similar during steady-state growth, being cytoplasmic and nuclear with good and poor nitrogen sources, respectively.	Nitrogen	116-124	Gat1p	Saccharomyces cerevisiae S288C	0-4
17487963-2	2007	For bulky nitrogen-based ligands, the strap can be displaced sideways to accommodate the ligand on the same side as the strap.	Nitrogen	10-18	serine/threonine kinase receptor associated protein	Homo sapiens	38-43
17487963-2	2007	For bulky nitrogen-based ligands, the strap can be displaced sideways to accommodate the ligand on the same side as the strap.	Nitrogen	10-18	serine/threonine kinase receptor associated protein	Homo sapiens	120-125
17562468-4	2007	LA and LG activities alone and their ratio with organic-C (ratio index value, RIV), straw and grain yield were higher in DCM than MSWC-treated soils, due to higher amount of biogenic organic materials like water-soluble organic carbon, carbohydrate and mineralizable nitrogen in the former.	Nitrogen	267-275	asparaginase and isoaspartyl peptidase 1	Bos taurus	0-2
17472841-4	2007	RESULTS: C3aR is a highly N-glycosylated protein with an apparent molecular mass of 65 to 95 kd expressed by myeloid and endothelial cells.	Nitrogen	26-27	complement C3a receptor 1	Homo sapiens	9-13
26555173-2	2015	Here, we delineate a pathway in which EGFR signaling, by increasing glucose uptake, promotes N-glycosylation of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and consequent activation of SREBP-1, an ER-bound transcription factor with central roles in lipid metabolism.	Nitrogen	93-94	CCHC-type zinc finger nucleic acid binding protein	Homo sapiens	155-160
26555173-2	2015	Here, we delineate a pathway in which EGFR signaling, by increasing glucose uptake, promotes N-glycosylation of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and consequent activation of SREBP-1, an ER-bound transcription factor with central roles in lipid metabolism.	Nitrogen	93-94	SREBF chaperone	Homo sapiens	191-195
26276083-6	2015	Studies showed the involvement of CYP1A2, CYP2B6, CYP2C19, and CYP3A4 in N-dealkylation of all three compounds and additionally CYP2D6 for lefetamine and NEDPA.	Nitrogen	73-74	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	42-48
17355124-1	2007	Glutamine synthetase adenylyltransferase (ATase) regulates the activity of glutamine synthetase by adenylylation and deadenylylation in response to signals of nitrogen and carbon status: glutamine, alpha-ketoglutarate, and the uridylylated and unmodified forms of the PII signal transduction protein.	Nitrogen	159-167	adenylyltransferase	Escherichia coli	21-40
16531813-0	2006	Influence of variable N-glycosylation on the cytolytic potential of chimeric CD19 antibodies.	Nitrogen	22-23	CD19 molecule	Homo sapiens	77-81
16482161-2	2006	Escherichia coli AlkB and the homologous human proteins ABH2 and ABH3 (refs 5, 7) promiscuously repair DNA and RNA bases damaged by S(N)2 alkylation reagents, which attach hydrocarbons to endocyclic ring nitrogen atoms (N1 of adenine and guanine and N3 of thymine and cytosine).	Nitrogen	204-212	alkB homolog 2, alpha-ketoglutarate dependent dioxygenase	Homo sapiens	56-60
16482161-2	2006	Escherichia coli AlkB and the homologous human proteins ABH2 and ABH3 (refs 5, 7) promiscuously repair DNA and RNA bases damaged by S(N)2 alkylation reagents, which attach hydrocarbons to endocyclic ring nitrogen atoms (N1 of adenine and guanine and N3 of thymine and cytosine).	Nitrogen	204-212	alkB homolog 3, alpha-ketoglutarate dependent dioxygenase	Homo sapiens	65-69
26415233-1	2015	In human SH-SY5Y neuroblastoma (NB) cells, nascent immature N-glycosylated 110kDa TrkA moves rapidly from the endoplasmic reticulum (ER) to the Golgi Network (GN), where it matures into the 140kDa receptor prior to being transported to the cell surface, creating GN and cell surface pools of inactive receptor maintained below the spontaneous activation threshold by a full compliment of inhibitory domains and endogenous PTPases.	Nitrogen	32-33	neurotrophic receptor tyrosine kinase 1	Homo sapiens	82-86
16862452-4	2006	The NMDA receptor NR1 subunit was characterized as being a heavily N-glycosylated protein.	Nitrogen	4-5	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	18-21
16352304-6	2006	Co-administration of N/OFQ (10(-10) M), the CSF concentration observed after brain injury, with U 46619 or PGF(2a) under non brain injury conditions potentiated prostaglandin vasoconstriction but U 0126 and SB 203580 blocked such potentiation.	Nitrogen	21-22	placenta growth factor	Sus scrofa	107-110
17338513-1	2007	This report describes the rapid and slow thermal decomposition of an energetically unstable polycyclic and heterocyclic azide, triazido-s-heptazine (C6N16), to produce nitrogen-rich CNx materials (x &gt; 1.2).	Nitrogen	168-176	calnexin	Homo sapiens	182-185
26395994-7	2015	Changes at N-glycosylation motifs were also detected in IL-1, IL-10, IL-12B and IL-15.	Nitrogen	11-12	interleukin-10	Oryctolagus cuniculus	62-67
17259447-3	2007	N-Demethylation of methadone in vitro is predominantly mediated by cytochrome P450 CYP3A4 and CYP2B6 and somewhat by CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	94-100
17259447-4	2007	This investigation evaluated stereoselectivity, models, and kinetic parameters for methadone N-demethylation by recombinant CYP2B6, CYP3A4, and CYP2C19, and the potential for interactions between enantiomers during racemate metabolism.	Nitrogen	93-94	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	124-130
16289480-3	2006	However, they showed only poor to moderate binding affinities, indicating that substitution of the C-4 pyrazole atom of the CB1 reference compound SR141716 by a nitrogen atom results in loss of affinity.	Nitrogen	161-169	cannabinoid receptor 1 (brain)	Mus musculus	124-127
26359303-6	2015	The mutated gene alg9 encodes a putative mannosyl transferase that participates in N-linked protein glycosylation.	Nitrogen	83-84	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	17-21
16230337-5	2005	The human beta2 subunit has eight N-glycosylation sites, whereas the beta1 isoform has only three.	Nitrogen	34-35	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	10-15
26285173-10	2015	SIGNIFICANCE: This ex vivo and in vitro study demonstrates that 2-DG inhibits angiogenesis with an action involving attenuation of VEGFR2 signaling and MMP-2 expression, possibly resulting from interference with N-linked glycosylation of VEGFR2.	Nitrogen	3-4	matrix metallopeptidase 2	Rattus norvegicus	152-157
16230337-6	2005	Accordingly, up to five additional N-glycosylation sites homologous to the ones present in the beta2 subunit were successively introduced in the beta1 subunit by site-directed mutagenesis.	Nitrogen	35-36	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	95-100
16342937-14	2005	Last, nearly all potential N-glycosylation sites are occupied in the rat zonae glycoproteins (three of three for ZP1, six or seven of seven for ZP2, and four or five of six for ZP3).	Nitrogen	27-28	zona pellucida glycoprotein 1	Rattus norvegicus	113-116
16323901-6	2005	TGA shows that the complex starts thermal decomposition upon heating in nitrogen atmosphere at 105 degrees C to produce barium cobalt oxide material of a Ba2CoO3 composition with an orthorhombic structure.	Nitrogen	72-80	T-box transcription factor 1	Homo sapiens	0-3
16034598-14	2005	GLU1 expression in vascular cells indicates that Fd-GOGAT provides amino acids for nitrogen translocation.	Nitrogen	83-91	glutamate synthase 1	Arabidopsis thaliana	0-4
17188508-6	2007	Simulations show that at 0.05 to 0.8 mTorr of nitrogen, it is possible to reduce the FRP bandwidth by 20% (measured at 50% depth).	Nitrogen	46-54	secreted frizzled related protein 1	Homo sapiens	85-88
17290224-1	2007	The C/EBPalpha transcription factor regulates hepatic nitrogen, glucose, lipid and iron metabolism.	Nitrogen	54-62	CCAAT/enhancer binding protein (C/EBP), alpha	Mus musculus	4-14
17264154-0	2007	Ribophorin I acts as a substrate-specific facilitator of N-glycosylation.	Nitrogen	57-58	ribophorin I	Homo sapiens	0-12
17264154-4	2007	We show that ribophorin I dramatically enhances the N-glycosylation of selected membrane proteins and provide evidence that it is not essential for N-glycosylation per se.	Nitrogen	52-53	ribophorin I	Homo sapiens	13-25
17215308-5	2007	This is the first report showing that modulation of N signaling by Fng is important for central nervous system development in any organism.	Nitrogen	52-53	fringe	Drosophila melanogaster	67-70
26187957-6	2015	Introduction of the Tn5 transposon into USDA61 resulted in the formation of nitrogen fixation nodules on the roots of soybean cultivar BARC2 (Rj4 Rj4).	Nitrogen	76-84	thaumatin-like protein 1	Glycine max	142-145
17270009-3	2007	Nitrogen limitation in Arabidopsis led to a decrease in the chloroplast galactolipid monogalactosyldiacylglycerol (MGDG) and a concomitant increase in digalactosyldiacylglycerol (DGDG), which correlated with an elevated expression of the DGDG synthase genes DGD1 and DGD2.	Nitrogen	0-8	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	258-262
16227401-6	2005	Thirty-five N-substituted analogues inhibited both p300/cyclic AMP-responsive element binding protein-binding protein-associated factor (PCAF) and p300 (1 to &gt;50 micromol/L, respectively) and the growth of a panel of human tumor cell lines (50% growth inhibition, 0.8 to &gt;50 micromol/L).	Nitrogen	12-13	E1A binding protein p300	Homo sapiens	51-55
16227401-6	2005	Thirty-five N-substituted analogues inhibited both p300/cyclic AMP-responsive element binding protein-binding protein-associated factor (PCAF) and p300 (1 to &gt;50 micromol/L, respectively) and the growth of a panel of human tumor cell lines (50% growth inhibition, 0.8 to &gt;50 micromol/L).	Nitrogen	12-13	lysine acetyltransferase 2B	Homo sapiens	137-141
26210528-4	2015	Nitrogen flux increased to 10.3 g N d(-1) m(-2) when shifting to MEC mode.	Nitrogen	0-8	C-C motif chemokine ligand 28	Sus scrofa	65-68
16227401-6	2005	Thirty-five N-substituted analogues inhibited both p300/cyclic AMP-responsive element binding protein-binding protein-associated factor (PCAF) and p300 (1 to &gt;50 micromol/L, respectively) and the growth of a panel of human tumor cell lines (50% growth inhibition, 0.8 to &gt;50 micromol/L).	Nitrogen	12-13	E1A binding protein p300	Homo sapiens	147-151
17114808-4	2007	Furthermore, we examined the membrane topology of LRAT through an N-linked glycosylation scanning approach and protease protection assays.	Nitrogen	66-67	lecithin retinol acyltransferase	Homo sapiens	50-54
26483804-0	2015	The transporter GAT1 plays an important role in GABA-mediated carbon-nitrogen interactions in Arabidopsis.	Nitrogen	69-77	Thioredoxin superfamily protein	Arabidopsis thaliana	16-20
17652782-12	2007	In contrast, the N-glycans unique to the Na,K-ATPase beta2-subunit,which has up to eight N-glycosylation sites, contain apical sorting information.	Nitrogen	17-18	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	53-58
16202243-11	2005	Nitrogen starvation was also able to induce the synthesis of beta-galactosidase from the GGTII-lacZ fusiongene in a Pap1-dependent manner.	Nitrogen	0-8	galactosidase beta 1	Homo sapiens	61-79
26212438-0	2015	The yeast chromatin remodeler Rsc1-RSC complex is required for transcriptional activation of autophagy-related genes and inhibition of the TORC1 pathway in response to nitrogen starvation.	Nitrogen	168-176	RSC subunit protein RSC1	Saccharomyces cerevisiae S288C	30-34
16156603-0	2005	Synthesis of multi-walled and bamboo-like well-crystalline CNx nanotubes with controllable nitrogen concentration (x = 0.05-1.02).	Nitrogen	91-99	calnexin	Homo sapiens	59-62
16156603-1	2005	The multi-walled and bamboo-like well-crystalline CNx nanotubes with controllable nitrogen concentration (x = 0.05-1.02) were synthesized.	Nitrogen	82-90	calnexin	Homo sapiens	50-53
17027085-1	2007	The neutral mononuclear copper complex with the quinolone antibacterial drug N-propyl-protected norfloxacin, Hpr-norfloxacin, in the presence of the nitrogen donor heterocyclic ligand 2,2"-bipyridine has been prepared and characterized.	Nitrogen	149-157	haptoglobin-related protein	Homo sapiens	109-112
25541284-2	2015	MOG has a single N-glycosylation site within its extracellular domain.	Nitrogen	17-18	myelin oligodendrocyte glycoprotein	Homo sapiens	0-3
17050611-5	2007	Upon prolonged exposure of HIV-1-infected CEM cell cultures, PRM-A drug pressure selects for mutant HIV-1 strains containing N-glycosylation site deletions in gp120 but not gp41.	Nitrogen	125-126	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	159-164
17085512-0	2007	Reciprocal leaf and root expression of AtAmt1.1 and root architectural changes in response to nitrogen starvation.	Nitrogen	94-102	ammonium transporter 1;1	Arabidopsis thaliana	39-47
17085512-3	2007	The promoter for the high-affinity ammonium transporter, AtAmt1.1, is shown to be a valid indicator for nitrogen status in leaves and roots.	Nitrogen	104-112	ammonium transporter 1;1	Arabidopsis thaliana	57-65
15931460-5	2005	Glycosidase analysis of cellular and secreted forms confirmed that Fpv060, Fpv061 and Fpv121 were N-glycosylated and that the most abundant, cellular form of Fpv061 had been glycosylated but remained Endo H-sensitive (retained in the endoplasmic reticulum or Golgi).	Nitrogen	98-99	CC chemokine gene family protein	Fowlpox virus	75-81
17085512-5	2007	The effects of nitrogen supply, light duration, light intensity, and carbon on the expression of the AtAmt1.1 gene in the roots and aerial tissues are reported.	Nitrogen	15-23	ammonium transporter 1;1	Arabidopsis thaliana	101-109
26109616-11	2015	Using co-precipitated integrin alpha5beta1 followed by phytohaemagglutinin (PHA)-L and PHA-E blotting, we investigated whether GnT-V and GnT-III could modify the N-glycosylation profile in terms of the beta1,6-GlcNAc and bis-GlcNAc structures in integrin alpha5beta1 during the first trimester in both groups.	Nitrogen	162-163	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	137-144
16006204-1	2005	Nitrogen-containing bisphosphonate drugs such as risedronate act by inhibiting farnesyl diphosphate synthase, thereby disrupting protein prenylation in osteoclasts.	Nitrogen	0-8	farnesyl diphosphate synthetase	Mus musculus	79-108
15823095-9	2005	Of the five members, only Lass2, Lass5 and Lass6 were N-glycosylated, each at their N-terminal Asn residue.	Nitrogen	54-55	ceramide synthase 6	Homo sapiens	43-48
15822115-10	2005	Limited peptide-N-glycanase-F treatment revealed that all four N-glycosylation sites are quantitatively occupied in PAG-1.	Nitrogen	16-17	pregnancy-associated glycoprotein 1	Bos taurus	116-121
15822115-11	2005	Compared to PAG-1 the number of potential N-glycosylation sites is lower in PAG-17 (three sites) and higher in PAG-6 and -7 (five and six sites, respectively).	Nitrogen	42-43	pregnancy-associated glycoprotein 1	Bos taurus	12-17
16889861-3	2006	While extracts from HeLa cells were very inefficient for production of an N-glycosylated form of human immunodeficiency virus type-1 envelope protein 120 (gp120), the hybridoma extract was able to fully N-glycosylate gp120.	Nitrogen	74-75	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	155-160
17149876-4	2006	Bases with a chlorine atom in the 6-position or a nitrogen in the 8-position exhibited strong discrimination between P. falciparum HGXPRT and human HGPRT.	Nitrogen	50-58	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	148-153
26343715-2	2015	Besides active transcription, expression of the active LPH requires different maturation steps of the polypeptide through the secretory pathway, including N- and O-glycosylation, dimerization and proteolytic cleavage steps.	Nitrogen	155-156	lactase	Homo sapiens	55-58
16877748-0	2006	N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry.	Nitrogen	0-1	intercellular adhesion molecule 1	Mus musculus	63-96
16877748-1	2006	Intercellular adhesion molecule-1 (ICAM-1) is a heavily N-glycosylated transmembrane protein comprising five extracellular Ig-like domains.	Nitrogen	56-57	intercellular adhesion molecule 1	Mus musculus	0-33
16877748-1	2006	Intercellular adhesion molecule-1 (ICAM-1) is a heavily N-glycosylated transmembrane protein comprising five extracellular Ig-like domains.	Nitrogen	56-57	intercellular adhesion molecule 1	Mus musculus	35-41
15723355-4	2005	Lithium induced the accumulation of N-terminally phosphorylated inactive form of GSK3beta with concomitant increase in beta-catenin and beta-catenin/TCF transcriptional activity in both cell lines.	Nitrogen	36-37	glycogen synthase kinase 3 beta	Homo sapiens	81-89
15919156-8	2005	Sialylated O-glycosylated proteins, such as bovine submaxillary gland mucin, human IgA, and fetuin, showed stronger inhibitory activity than sialylated N-glycosylated proteins, such as human orosomucoid, IgG, transferrin, and lactoferrin.	Nitrogen	152-153	mucin 1, cell surface associated	Bos taurus	70-75
26172854-2	2015	Nutritional signals including nitrogen availability are integrated by the TORC1 complex which notably regulates arrestin-mediated endocytosis of amino-acid transporters.	Nitrogen	30-38	CREB regulated transcription coactivator 1	Homo sapiens	74-79
15917935-1	2005	A first example of an enantioselective catalytic diamination of olefins has been developed which employs enantiopure titanium complexes as catalysts and bis(tbutylimido)dioxoosmium(VIII) as nitrogen source.	Nitrogen	190-198	cytochrome c oxidase subunit 8A	Homo sapiens	181-185
17125209-5	2006	Similarly, most UGT isoforms were found to have a statistically significant preference for oxygen over nitrogen as the nucleophilic atom.	Nitrogen	103-111	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	16-19
26172854-6	2015	We show that, under poor nitrogen supply, the TORC1 effector kinase" Npr1" promotes phosphorylation of Amu1/Par32 which appears mainly cytosolic while ammonium transport proteins are active.	Nitrogen	25-33	CREB regulated transcription coactivator 1	Homo sapiens	46-51
26172854-7	2015	Upon preferred nitrogen supplementation, like glutamine or ammonium addition, TORC1 upregulation enables Npr1 inhibition and Amu1/Par32 dephosphorylation.	Nitrogen	15-23	CREB regulated transcription coactivator 1	Homo sapiens	78-83
25916169-4	2015	The present study explores the occupancy and relevance for intracellular trafficking and enzyme activity of these potential N-glycosylations in human ST3Gal-II.	Nitrogen	124-125	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	Homo sapiens	150-159
16738862-3	2006	One member of this family has been characterized as an N-acylethanolamine-cleaving fatty acid amidohydrolase (FAAH) and two other members are part of the preprotein translocon of the outer envelope of chloroplasts (Toc complex) or mitochondria (Tom complex) and presumably lack enzymatic activity.	Nitrogen	55-56	fatty acid amide hydrolase	Arabidopsis thaliana	110-114
17029379-6	2006	N2-sorption experiments show 3 has a relatively high BET surface area of 750 m(2)/g.	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	53-56
17029381-3	2006	The X-ray crystal structures of these new complexes were determined, and the solid-state structures consist of the nitrogen heterocycles bonded to the (18-crown-6)potassium cationic fragments with eta2-bonding interactions.	Nitrogen	115-123	DNA polymerase iota	Homo sapiens	197-201
15933030-4	2005	Transcript level analysis revealed that among the five thiamine-pyrophospate-dependent decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3), only ARO10 was transcriptionally up-regulated when phenylalanine, leucine, or methionine was used as a nitrogen source compared to growth on ammonia, proline, and asparagine.	Nitrogen	242-250	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	144-149
15933030-6	2005	Constitutive expression of ARO10 in ethanol-limited chemostat cultures in a strain lacking the five thiamine-pyrophosphate-dependent decarboxylases, grown with ammonia as a nitrogen source, led to a measurable decarboxylase activity with phenylalanine-, leucine-, and methionine-derived 2-oxo acids.	Nitrogen	173-181	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	27-32
15925308-4	2005	While the rns4 mutant exhibited sensitivity to ambient stress conditions (200 mM CaCl(2), 1M NaCl and pH 8.0), genome-wide expression analysis revealed a similar pattern of genes up-regulated as was observed under nitrogen depletion condition by Gasch et al.	Nitrogen	214-222	ESCRT-III subunit protein SNF7	Saccharomyces cerevisiae S288C	10-14
25916169-6	2015	By pharmacological, biochemical and site-directed mutagenesis, we observed that ST3Gal-II is mostly N-glycosylated at Asn(211) and that this co-translational modification is critical for its exit from the endoplasmic reticulum and proper Golgi localization.	Nitrogen	100-101	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	Homo sapiens	80-89
25916169-7	2015	The individual N-glycosylation sites had different effects on ST3Gal-II enzymatic activity.	Nitrogen	15-16	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	Homo sapiens	62-71
25916169-10	2015	This suggests that the C-terminal domain of ST3Gal-II depends on N-glycosylation to attain an optimum conformation for proper exit from the endoplasmic reticulum, but it does not represent an absolute requirement for Golgi complex retention of the enzyme.	Nitrogen	65-66	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	Homo sapiens	44-53
16019536-3	2005	We now report that a staurosporine derivative, N-benzoylated staurosporine or PKC412, induces cell death in myeloma cell lines (RPMI8226S, U266, MM1S and MM1R) with loss of mitochondrial membrane potential Delta psi m, caspase 3 and PARP cleavage.	Nitrogen	47-48	collagen type XI alpha 2 chain	Homo sapiens	233-237
16935263-2	2006	Reportedly, abnormal N-linked glycosylation patterns in PrPC are associated with disease susceptibility; thus, we compared the glycosylation status of normal and several mutant forms of the murine prion protein (MuPrP) in cultured mammalian cells.	Nitrogen	21-22	prion protein	Mus musculus	56-60
26121645-6	2015	The potential functional role of the presence of N-glycans near disulphide bridges in HIV-1 gp120 was studied using site-directed mutagenesis, either by deleting conserved N-glycans or by inserting new N-glycosylation sites near disulphide bridges.	Nitrogen	49-50	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	92-97
16855013-0	2006	Nitrogen fixation by white lupin under phosphorus deficiency.	Nitrogen	0-8	5'-nucleotidase, cytosolic IIIA	Homo sapiens	27-32
17050187-3	2006	A leave-one-out (LOO) cross validation procedure resulted in the selection of three descriptors, the total of electron and nuclear energies of the two-center terms for the carbon-chlorine or carbon-nitrogen bond (TE2), the net atomic charges on the chlorine or nitrogen (qx), and the largest negative atomic charge on an atom (q-).	Nitrogen	198-206	N-alpha-acetyltransferase 10, NatA catalytic subunit	Homo sapiens	213-216
15968392-10	2005	In conclusion, although the FXI-T475I mutation destroys an N-linked glycosylation consensus sequence, the cause of failure to secrete FXI is not the loss of a glycosylation site but rather a direct effect of the substitution of this highly conserved residue.	Nitrogen	59-60	coagulation factor XI	Homo sapiens	28-31
19791408-1	2005	The kinetics of the gas phase HO2 self-reaction have been studied using flash photolysis of Cl2/CH3OH/O2/N2 mixtures coupled with time-resolved broadband UV absorption spectroscopy.	Nitrogen	105-107	heme oxygenase 2	Homo sapiens	30-33
15757902-5	2005	Disruption of the N-capping motif of helix 9 in hGST A1-1 alters the conformational dynamics of the C-terminal region and, consequently, the features of the H-site to which hydrophobic substrates (e.g. 1-chloro-2,4-dinitrobenzene (CDNB)) and nonsubstrates (e.g. 8-anilino-1-naphthalene sulfonate (ANS)) bind.	Nitrogen	18-19	glutathione S-transferase alpha 1	Homo sapiens	48-57
25927686-5	2015	N2-physisorption analysis revealed a BET surface area of 394 m(2) g(-1) and a pore volume around 0.55 cm(3) g(-1).	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	37-40
15840509-1	2005	A simple and sensitive method for determination of the N-glucuronidation activity of mouse, rat, and human liver microsomes toward the carcinogenic arylamine 4-aminobiphenyl (4-ABP) using high-performance liquid chromatography with ultraviolet detection has been developed.	Nitrogen	55-56	amine oxidase copper containing 1	Homo sapiens	177-180
16735122-1	2006	Thyrotropin-releasing hormone (TRH) analogues in which the N(1)-position of the imidazole ring of the centrally placed histidine residue is substituted with various alkyl groups were synthesized and studied as agonists for TRH receptor subtype 1 (TRH-R1) and subtype 2 (TRH-R2).	Nitrogen	59-60	thyrotropin releasing hormone	Homo sapiens	0-29
16735122-1	2006	Thyrotropin-releasing hormone (TRH) analogues in which the N(1)-position of the imidazole ring of the centrally placed histidine residue is substituted with various alkyl groups were synthesized and studied as agonists for TRH receptor subtype 1 (TRH-R1) and subtype 2 (TRH-R2).	Nitrogen	59-60	thyrotropin releasing hormone	Homo sapiens	31-34
17091764-4	2006	What is not generally realized is that asparaginase also catalyzes, essentially to the same extent, the removal of the amide nitrogen from glutamine to form glutamic acid.	Nitrogen	125-133	asparaginase	Homo sapiens	39-51
25855336-3	2015	Further UV-vis and photoluminescence analyses show a red shift of the emission peak after repeated EDA treatment, which might be attributed to the formation of imine conjugation from newly formed carbon-nitrogen bonds on the PAN backbone.	Nitrogen	203-211	ectodysplasin A	Homo sapiens	99-102
16220781-5	2005	8, 4 and 20 mg x L(-1), P &gt; 0.05 vs LPS group), but the activity of COX-2 enzyme was significantly inhibited by 10 micromol x L(-01) NS-398 (P &lt; 0.01 vs LPS group).	Nitrogen	136-138	cytochrome c oxidase II, mitochondrial	Mus musculus	71-76
25382626-0	2015	The plasma membrane H(+) -ATPase AHA2 contributes to the root architecture in response to different nitrogen supply.	Nitrogen	100-108	plasma membrane H+-ATPase	Arabidopsis thaliana	4-32
15823039-3	2005	We report here that part of the extranuclear nucleolin undergoes complex N- and O-glycosylations.	Nitrogen	73-74	nucleolin	Homo sapiens	45-54
16967194-3	2006	However, the predominant contribution to nitrogen relaxation from 15N-(1)H dipolar coupling in amide groups limits the sensitivity of these measurements to the actual CSA values.	Nitrogen	41-49	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	167-170
16910661-1	2006	Nitrogen-carbon bond formation from coordinated dinitrogen has been observed upon addition of 2 equiv of PhNCO to the hafnocene dinitrogen complex, [(eta5-C5Me4H)2Hf]2(mu2,eta2,eta2-N2).	Nitrogen	0-8	DNA polymerase iota	Homo sapiens	172-176
16910661-1	2006	Nitrogen-carbon bond formation from coordinated dinitrogen has been observed upon addition of 2 equiv of PhNCO to the hafnocene dinitrogen complex, [(eta5-C5Me4H)2Hf]2(mu2,eta2,eta2-N2).	Nitrogen	0-8	DNA polymerase iota	Homo sapiens	177-181
15537386-5	2005	Remarkably, introduction of the Asp144--&gt;Asn mutation into rabbit GnTI, which does not result in the formation of a new N-glycosylation site, led to a protein with strongly reduced, but still detectable enzymic activity.	Nitrogen	123-124	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Oryctolagus cuniculus	69-73
16910661-1	2006	Nitrogen-carbon bond formation from coordinated dinitrogen has been observed upon addition of 2 equiv of PhNCO to the hafnocene dinitrogen complex, [(eta5-C5Me4H)2Hf]2(mu2,eta2,eta2-N2).	Nitrogen	48-58	DNA polymerase iota	Homo sapiens	172-176
25382626-1	2015	In this study the role of the plasma membrane (PM) H(+) -ATPase for growth and development of roots as response to nitrogen starvation is studied.	Nitrogen	115-123	plasma membrane H+-ATPase	Arabidopsis thaliana	30-63
16910661-1	2006	Nitrogen-carbon bond formation from coordinated dinitrogen has been observed upon addition of 2 equiv of PhNCO to the hafnocene dinitrogen complex, [(eta5-C5Me4H)2Hf]2(mu2,eta2,eta2-N2).	Nitrogen	48-58	DNA polymerase iota	Homo sapiens	177-181
25382626-8	2015	This suggests that the PM proton pump AHA2 (Arabidopsis plasma membrane H(+) -ATPase isoform 2) is important for root growth and development during different nitrogen regimes.	Nitrogen	158-166	plasma membrane H+-ATPase	Arabidopsis thaliana	56-84
25922058-4	2015	A TAR1-defective mutant, tar1-1, accumulated TAG to levels 0.5- and 0.1-fold of those of a wild-type strain in sulfur (S)- and nitrogen (N)-deficient conditions, respectively.	Nitrogen	127-135	Tar1p	Saccharomyces cerevisiae S288C	25-31
16872554-9	2006	The observed changes indicate an impairment of N-deethylation metabolic pathway in streptozotocin-induced diabetic rats, i.e. a possible decrease in the enzymatic activity of CYP3A2 and CYP1A2.	Nitrogen	47-48	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	175-181
16833643-1	2005	Transient absorption spectra and decay profiles of HO2 have been measured using cw near-IR two-tone frequency modulation absorption spectroscopy at 297 K and 50 Torr in diluent of N2 in the presence of water.	Nitrogen	180-182	heme oxygenase 2	Homo sapiens	51-54
16833643-2	2005	From the depletion of the HO2 absorption peak area following the addition of water, the equilibrium constant of the reaction HO2 + H2O &lt;--&gt; HO2-H2O was determined to be K2 = (5.2 +/- 3.2) x 10(-19) cm3 molecule(-1) at 297 K. Substituting K2 into the water dependence of the HO2 decay rate, the rate coefficient of the reaction HO2 + HO2-H2O was estimated to be (1.5 +/- 0.1) x 10(-11) cm3 molecule(-1) s(-1) at 297 K and 50 Torr with N2 as the diluent.	Nitrogen	440-442	heme oxygenase 2	Homo sapiens	26-29
16833643-2	2005	From the depletion of the HO2 absorption peak area following the addition of water, the equilibrium constant of the reaction HO2 + H2O &lt;--&gt; HO2-H2O was determined to be K2 = (5.2 +/- 3.2) x 10(-19) cm3 molecule(-1) at 297 K. Substituting K2 into the water dependence of the HO2 decay rate, the rate coefficient of the reaction HO2 + HO2-H2O was estimated to be (1.5 +/- 0.1) x 10(-11) cm3 molecule(-1) s(-1) at 297 K and 50 Torr with N2 as the diluent.	Nitrogen	440-442	heme oxygenase 2	Homo sapiens	125-128
16833643-2	2005	From the depletion of the HO2 absorption peak area following the addition of water, the equilibrium constant of the reaction HO2 + H2O &lt;--&gt; HO2-H2O was determined to be K2 = (5.2 +/- 3.2) x 10(-19) cm3 molecule(-1) at 297 K. Substituting K2 into the water dependence of the HO2 decay rate, the rate coefficient of the reaction HO2 + HO2-H2O was estimated to be (1.5 +/- 0.1) x 10(-11) cm3 molecule(-1) s(-1) at 297 K and 50 Torr with N2 as the diluent.	Nitrogen	440-442	heme oxygenase 2	Homo sapiens	125-128
16833643-2	2005	From the depletion of the HO2 absorption peak area following the addition of water, the equilibrium constant of the reaction HO2 + H2O &lt;--&gt; HO2-H2O was determined to be K2 = (5.2 +/- 3.2) x 10(-19) cm3 molecule(-1) at 297 K. Substituting K2 into the water dependence of the HO2 decay rate, the rate coefficient of the reaction HO2 + HO2-H2O was estimated to be (1.5 +/- 0.1) x 10(-11) cm3 molecule(-1) s(-1) at 297 K and 50 Torr with N2 as the diluent.	Nitrogen	440-442	heme oxygenase 2	Homo sapiens	125-128
16833643-2	2005	From the depletion of the HO2 absorption peak area following the addition of water, the equilibrium constant of the reaction HO2 + H2O &lt;--&gt; HO2-H2O was determined to be K2 = (5.2 +/- 3.2) x 10(-19) cm3 molecule(-1) at 297 K. Substituting K2 into the water dependence of the HO2 decay rate, the rate coefficient of the reaction HO2 + HO2-H2O was estimated to be (1.5 +/- 0.1) x 10(-11) cm3 molecule(-1) s(-1) at 297 K and 50 Torr with N2 as the diluent.	Nitrogen	440-442	heme oxygenase 2	Homo sapiens	125-128
16833643-2	2005	From the depletion of the HO2 absorption peak area following the addition of water, the equilibrium constant of the reaction HO2 + H2O &lt;--&gt; HO2-H2O was determined to be K2 = (5.2 +/- 3.2) x 10(-19) cm3 molecule(-1) at 297 K. Substituting K2 into the water dependence of the HO2 decay rate, the rate coefficient of the reaction HO2 + HO2-H2O was estimated to be (1.5 +/- 0.1) x 10(-11) cm3 molecule(-1) s(-1) at 297 K and 50 Torr with N2 as the diluent.	Nitrogen	440-442	heme oxygenase 2	Homo sapiens	125-128
15784490-11	2005	Co-administration of MVP with lipid or light protected amino acids offers comparable beneficial effects on nitrogen and vitamin C metabolism.	Nitrogen	107-115	major vault protein	Homo sapiens	21-24
15745801-1	2005	Attachment of a glucose moiety to 6-beta-aminomorphine afforded compound 3, where the glucose moiety was linked to the C-6 nitrogen atom by a two-carbon bridge.	Nitrogen	123-131	complement C6	Homo sapiens	119-122
16822331-5	2006	Deglycosylation studies using endoglycohydrolases that delete N-linked oligosaccharides (OS) from the molecule show that TEX101 is highly (approximately 47%) N-glycosylated.	Nitrogen	62-63	testis expressed gene 101	Mus musculus	121-127
16822331-6	2006	All potential N-glycosylation sites within TEX101 are glycosylated and most of these sites are occupied by endoglycosidase F2-sensitive biantennary complex type OS units.	Nitrogen	14-15	testis expressed gene 101	Mus musculus	43-49
16821877-1	2006	This behavior of the SPR band, upon exposure to CO, was not observed when using nitrogen as the carrier gas, indicating an oxygen-dependent reaction mechanism.	Nitrogen	80-88	sepiapterin reductase	Homo sapiens	21-24
16813429-5	2006	The [SNO][NN] mixed-ligand system was applied in the synthesis of the oxorhenium complex 5 in which the 1-(2-methoxyphenyl)piperazine moiety, a fragment of the true 5-HT1A antagonist WAY 100635, has been incorporated in the NN bidentate ligand (NN is N-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}pyridine-2-aldimine).	Nitrogen	10-12	strawberry notch homolog 1	Homo sapiens	5-8
16813429-5	2006	The [SNO][NN] mixed-ligand system was applied in the synthesis of the oxorhenium complex 5 in which the 1-(2-methoxyphenyl)piperazine moiety, a fragment of the true 5-HT1A antagonist WAY 100635, has been incorporated in the NN bidentate ligand (NN is N-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}pyridine-2-aldimine).	Nitrogen	224-226	strawberry notch homolog 1	Homo sapiens	5-8
25898142-5	2015	(1) displays a reversible type-I sorption isotherm for CO2 and N2 with BET surface areas of 196 and 319 m(2)/g, respectively.	Nitrogen	63-65	delta/notch like EGF repeat containing	Homo sapiens	71-74
16684511-4	2006	To further detect cPKC and nPKC isoforms activation following prolonged hypoxia in vitro, we tested the membrane translocation (an indicator of PKC activation) of cPKCalpha, betaI, betaII, and gamma, and nPKCdelta, epsilon, eta, mu, and theta in a human neuroblastoma SH-SY5Y cell line following sustained hypoxic exposure (1% O(2)/5% CO(2)/94% N(2)).	Nitrogen	345-349	protein kinase C delta	Homo sapiens	163-242
15615721-6	2005	Expression of GnT-V cDNA in the null MEF reversed these abnormal characteristics, indicating the direct involvement of N-glycosylation events in these phenotypic changes.	Nitrogen	22-23	mannoside acetylglucosaminyltransferase 5	Mus musculus	14-19
25898142-7	2015	A solvent exchange to give (2)-MeOH allowed for increased CO2 and N2 adsorption onto the MOF surface with BET surface areas of 41 and 39 m(2)/g, respectively.	Nitrogen	66-68	delta/notch like EGF repeat containing	Homo sapiens	106-109
26259481-0	2015	[Effects of transporter Agp1p ubiquitination on nitrogen utilization in Saccharomyces cerevisiae].	Nitrogen	48-56	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	24-29
15689404-5	2005	When pretreated with G-CSF or G-CSF + M-CSF, the mice showed longer survival and lower serum creatinine and blood urea nitrogen levels than mice that had been received injections of M-CSF or saline.	Nitrogen	119-127	peripheral blood stem cell response to granulocyte colony stimulating factor 1	Mus musculus	21-26
15689404-5	2005	When pretreated with G-CSF or G-CSF + M-CSF, the mice showed longer survival and lower serum creatinine and blood urea nitrogen levels than mice that had been received injections of M-CSF or saline.	Nitrogen	119-127	peripheral blood stem cell response to granulocyte colony stimulating factor 1	Mus musculus	30-35
15743966-8	2005	A chloride ion and a glycerol molecule were modeled in the active site where the chloride ion interacts in a manner similar to that of phosphate with the main chain nitrogens of the PTP loop.	Nitrogen	165-174	protein tyrosine phosphatase receptor type U	Homo sapiens	182-185
16722621-1	2006	New pentacyclic inhibitors of the P-glycoprotein carrying nitrogen-containing alkyl chains were synthesized and evaluated for MDR reverting activity on mouse lymphoma cells infected with pHa MDR1/A retrovirus.	Nitrogen	58-66	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	Mus musculus	191-197
16543229-1	2006	In the yeast Hansenula polymorpha, the YNT1 gene encodes the high affinity nitrate transporter, which is repressed by reduced nitrogen sources such as ammonium or glutamine.	Nitrogen	126-134	proteasome regulatory particle base subunit RPT3	Saccharomyces cerevisiae S288C	39-43
26259481-1	2015	OBJECTIVE: The purpose of this work is to studythe effects of ubiquitination of key nitrogen transporter Agp1p on nitrogen utilization in Saccharomyces cerevisiae.	Nitrogen	84-92	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	105-110
25164156-7	2015	In general, a significantly decreased expression of CD54, CD80, and HLA-DR membrane antigens was observed after 24 h of treatment with each nitrogen-containing bisphosphonate (p &lt; 0.05), but there was no significant difference in phagocytic activity versus controls.	Nitrogen	140-148	CD80 molecule	Homo sapiens	58-62
16563432-12	2006	These results suggest that the N-glyco side-chain of AMFR is a trigger and that interaction between the 117-C-terminal part of AMF and the extracellular core protein of AMFR is needed during AMF-AMFR interactions.	Nitrogen	31-32	glucose-6-phosphate isomerase	Homo sapiens	53-56
16563432-12	2006	These results suggest that the N-glyco side-chain of AMFR is a trigger and that interaction between the 117-C-terminal part of AMF and the extracellular core protein of AMFR is needed during AMF-AMFR interactions.	Nitrogen	31-32	glucose-6-phosphate isomerase	Homo sapiens	127-130
26626685-1	2006	We have used density functional calculations to examine the (101) surfaces of KDP, under vacuum, nitrogen, and aqueous conditions, and these simulations are found to agree well with nanoscale experimental studies demonstrating that the density functional calculations are providing a good description of the surfaces of this complex inorganic salt.	Nitrogen	97-105	WNK lysine deficient protein kinase 1	Homo sapiens	78-81
16480962-6	2006	Only UGT1A4 catalyzed the N-linked glucuronidation of 4-HO-TAM among recombinant human UGT isoforms (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A10, UGT2B4, UGT2B7, UGT2B15, and UGT2B17) expressed in insect cells.	Nitrogen	26-27	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	5-8
15728506-4	2005	In addition, unlike TLR1 and TLR6, TLR10 was expressed in a highly restricted fashion as a highly N-glycosylated protein, which we detected in B cell lines, B cells from peripheral blood, and plasmacytoid dendritic cells from tonsil.	Nitrogen	98-99	toll like receptor 10	Homo sapiens	35-40
15644514-10	2005	Urinary N loss was decreased (P = 0.05) by GLU and STA, but overall (feces plus urine) N losses were not affected (P = 0.73) by treatment.	Nitrogen	8-9	STA	Bos taurus	51-54
15644514-12	2005	The proportion of bacterial N synthesized from ammonia in the rumen was greater with STA than with NDF and MIX and was least for GLU (P = 0.02).	Nitrogen	28-29	STA	Bos taurus	85-88
16459807-1	2005	Wastewater discharge from coal refining plants contains a number of biologically toxic compounds; 2000-2500 mg/l of COD of which 40% is composed of phenol, 100-400 mg/l of thiocyanate, 10-40 mg/l of cyanide, 100-250 mg/l of NH4+-N and 150-300 mg/l of total nitrogen.	Nitrogen	257-265	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	116-119
25673816-5	2015	We observed maximum heightened odds of suicide associated with interquartile-range increases in nitrogen dioxide during cumulative lag 3 (average of the 3 days preceding suicide; odds ratio (OR) = 1.20, 95% confidence interval (CI): 1.04, 1.39) and fine particulate matter (diameter &lt;=2.5 mum) on lag day 2 (day 2 before suicide; OR = 1.05, 95% CI: 1.01, 1.10).	Nitrogen	96-104	lymphocyte activating 3	Homo sapiens	131-136
15556773-1	2004	In the course of chemical modification of alpha-fucosidase inhibitors of 5a-carba-fucopyranosylamine type, an N-dodecyl derivative of the enantiomer 6-deoxy-5a-carba-beta-D-galactopyranosylamine demonstrated very strong inhibition of beta-galactosidase and beta-glucosidase.	Nitrogen	110-111	galactosidase beta 1	Homo sapiens	234-252
16672275-4	2006	The deficiency of functional Arp4 caused a highly increased sensitivity towards nitrogen starvation and to the macrolide antibiotic rapamycin.	Nitrogen	80-88	Arp4p	Saccharomyces cerevisiae S288C	29-33
26045825-9	2015	Furthermore, serum OIF had negative correlation with estimated glomerular filtration rate (eGFR) and positive correlation with blood urea nitrogen(BUN) and creatinine.	Nitrogen	138-146	osteoglycin	Homo sapiens	19-22
16514458-1	2006	Zeise"s anion in strongly basic hydroxylated solvents undergoes unprecedented nucleophilic addition of OR- (R = H, Me, Et) to the eta2-ethene giving trans-[PtCl2(eta1-C2H4OR)(OR)]2- which readily reacts with bidentate nitrogen donors N-N to give Cl- and OR- substitution and formation of [PtCl(CH2CH2OR)(N-N)].	Nitrogen	218-226	DNA polymerase iota	Homo sapiens	130-134
16468990-4	2006	In nitrogen-starved cells, ammonium transport and activation of trehalase are most active in strains expressing either the Mep2 or Mep1 ammonium permease, as opposed to Mep3.	Nitrogen	3-11	ammonium permease MEP1	Saccharomyces cerevisiae S288C	131-135
15585841-0	2004	N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells.	Nitrogen	0-1	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
15566287-5	2004	Homology modeling and docking studies support experimental data and highlight the crucial role for the hydrogen bond between the pyridine nitrogen in position 3 of 5 and the NH-indole ring of Trp6.48, which is favorably oriented in the alpha(2C)-subtype, only.	Nitrogen	138-146	transient receptor potential cation channel subfamily C member 6	Homo sapiens	192-196
25588735-8	2015	Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant.	Nitrogen	196-204	phosphoenolpyruvate carboxylase 2	Arabidopsis thaliana	127-131
15292462-3	2004	To date the uridine diphosphate glucuronosyltransferase (UGT) isoform responsible for the N-glucuronidation of CBZ has not been identified.	Nitrogen	90-91	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	12-55
15292462-3	2004	To date the uridine diphosphate glucuronosyltransferase (UGT) isoform responsible for the N-glucuronidation of CBZ has not been identified.	Nitrogen	90-91	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	57-60
16337230-1	2006	In Saccharomyces cerevisiae, signal transduction through pathways governing mating, osmoregulation, and nitrogen starvation depends upon a direct interaction between the sterile alpha motif (SAM) domains of the Ste11 mitogen-activated protein kinase kinase kinase (MAPKKK) and its regulator Ste50.	Nitrogen	104-112	mitogen-activated protein kinase kinase kinase STE11	Saccharomyces cerevisiae S288C	211-216
25588735-8	2015	Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant.	Nitrogen	196-204	phosphoenolpyruvate carboxylase 2	Arabidopsis thaliana	324-328
25639242-0	2015	Nitrogen regulates AMPK to control TORC1 signaling.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	35-40
16471816-2	2006	A thin layer of HCl-2-propanol solution was frozen-in on the semiconductor GaAs(100) wafer surface by cooling the substrate to liquid nitrogen temperature after etching off the native oxide layer under N2 atmosphere.	Nitrogen	134-142	HCL2	Homo sapiens	16-21
16471816-2	2006	A thin layer of HCl-2-propanol solution was frozen-in on the semiconductor GaAs(100) wafer surface by cooling the substrate to liquid nitrogen temperature after etching off the native oxide layer under N2 atmosphere.	Nitrogen	202-204	HCL2	Homo sapiens	16-21
15542393-0	2004	Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein.	Nitrogen	0-1	NPC intracellular cholesterol transporter 2	Homo sapiens	107-111
15542393-4	2004	The present work was focused on localization and N-glycosylation of NPC2, considering that glycosylation is often essential for targeting, stability and biological function of proteins.	Nitrogen	49-50	NPC intracellular cholesterol transporter 2	Homo sapiens	68-72
25639242-3	2015	RESULTS: Here, we show that cells can sense nitrogen stress to reduce target of rapamycin complex-1 (TORC1) activity.	Nitrogen	44-52	CREB regulated transcription coactivator 1	Homo sapiens	70-99
25639242-3	2015	RESULTS: Here, we show that cells can sense nitrogen stress to reduce target of rapamycin complex-1 (TORC1) activity.	Nitrogen	44-52	CREB regulated transcription coactivator 1	Homo sapiens	101-106
16701529-4	2004	Similarly, for the COD to NO(3)-N ratios varying between 2 and 3.75 maximum denitrification was observed.	Nitrogen	26-27	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	19-22
15488758-1	2004	We identify a novel alternative TrkA splice variant, TrkAIII, with deletion of exons 6, 7, and 9 and functional extracellular IG-C1 and N-glycosylation domains, that exhibits expression restricted to undifferentiated early neural progenitors, human neuroblastomas (NBs), and a subset of other neural crest-derived tumors.	Nitrogen	136-137	neurotrophic receptor tyrosine kinase 1	Homo sapiens	32-36
16165408-1	2006	Geranylgeranyl pyrophosphate (GGPP) and geranylgeraniol (GGOH) are used for the prenylation of GTP binding proteins and can reverse the antiresorptive action of nitrogen-containing bisphosphonates which inhibit farnesyl pyrophosphate synthase, an enzyme of the mevalonate pathway involved in the formation of GGPP.	Nitrogen	161-169	farnesyl diphosphate synthetase	Mus musculus	211-242
16492559-3	2006	Biochemical and crystallographic data suggest that p35-N circularization results from the trapping of a native chemical ligation intermediate in the p35/caspase complex, in which the N-terminal Cys2 of p35 attacks the Asp87-Cys360" thioester to form an equilibrium between Asp87-Cys2 and Asp87-Cys360".	Nitrogen	55-56	caspase 8	Homo sapiens	153-160
16441371-8	2006	One of the mutant strains (BDCS-N-M36) exhibited very negligible expression of beta-lactamase activity and twofold increase in PGA activity [12.7 mg 6-amino-penicillanic acid (6-APA) h(-1) mg(-1) wet cells] compared with that in the wild-type strain (6.3 mg 6-APA h(-1) mg(-1) wet cells).	Nitrogen	32-33	beta-lactamase	Escherichia coli	79-93
15365656-9	2004	CONCLUSION: CYP2B6, CYP2C8, CYP2D6, and CYP3A4 catalyze LOP N-demethylation in human liver microsomes, and among them, CYP2C8 and CYP3A4 may play a crucial role in LOP metabolism at the therapeutic concentrations of LOP.	Nitrogen	2-3	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	12-18
15365656-9	2004	CONCLUSION: CYP2B6, CYP2C8, CYP2D6, and CYP3A4 catalyze LOP N-demethylation in human liver microsomes, and among them, CYP2C8 and CYP3A4 may play a crucial role in LOP metabolism at the therapeutic concentrations of LOP.	Nitrogen	2-3	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	20-26
25639242-4	2015	Nitrogen-stress-induced TORC1 inhibition differs from amino-acid-dependent control of TORC1 and requires the Ssp2 (AMPKalpha) kinase, the Tsc1/2 complex, and Rhb1 GTPase.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	24-29
15365656-9	2004	CONCLUSION: CYP2B6, CYP2C8, CYP2D6, and CYP3A4 catalyze LOP N-demethylation in human liver microsomes, and among them, CYP2C8 and CYP3A4 may play a crucial role in LOP metabolism at the therapeutic concentrations of LOP.	Nitrogen	2-3	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	119-125
25639242-4	2015	Nitrogen-stress-induced TORC1 inhibition differs from amino-acid-dependent control of TORC1 and requires the Ssp2 (AMPKalpha) kinase, the Tsc1/2 complex, and Rhb1 GTPase.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	86-91
17168726-7	2006	Most often, adenosine A(1) receptor non-xanthine antagonists are adenine-based, having substituted amino group and variable nitrogen atoms positions in the molecules.	Nitrogen	124-132	adenosine A1 receptor	Homo sapiens	12-35
25639242-9	2015	CONCLUSIONS: The alternative nitrogen source ammonia can simulate TORC1 activity to support growth and division under challenging nutrient settings, a situation often seen in cancer.	Nitrogen	29-37	CREB regulated transcription coactivator 1	Homo sapiens	66-71
25537499-1	2015	UV photolysis of the nitridoosmate(VIII) anion, OsO3 N(-) , in low-temperature frozen matrices results in nitrogen-oxygen bond formation to give the Os(II) nitrosyl complex OsO2 (NO)(-) .	Nitrogen	106-114	cytochrome c oxidase subunit 8A	Homo sapiens	35-39
16366575-4	2005	The metal-free N-nitrosylated ligand (DAC-NO + H)+ has two conformations: one family of structures has one anthracenyl group above the cyclam and one below, while the other has both anthracenyl groups on the same side of the cyclam.	Nitrogen	15-16	arylacetamide deacetylase	Homo sapiens	38-41
25490879-3	2015	In the process, the indole unit of L1 is deprotonated by the metal alkyl species and the imino C=N group is transferred to the amido group by alkyl CH2 SiMe3 insertion, affording a new dianionic ligand that bridges two metal alkyl units in mu-eta(2) :eta(1) :eta(1) bonding modes, forming the dinuclear rare-earth metal alkyl complexes.	Nitrogen	97-98	DNA polymerase iota	Homo sapiens	243-249
16235022-1	2005	The requirement for the mobA gene in key assimilatory and respiratory nitrogen metabolism of Pseudomonas aeruginosa PAO1 was investigated by mutational analysis of PA3030 (mobA; MoCo guanylating enzyme), PA1779 (nasA; assimilatory nitrate reductase), and PA3875 (narG; respiratory nitrate reductase).	Nitrogen	70-78	molybdenum cofactor guanylyltransferase	Pseudomonas aeruginosa PAO1	24-28
25478996-5	2015	This stable metal-organic framework (MOF) contains nanoscale holes and non-coordinating nitrogen atoms inside the walls of the holes, which makes it a potential host for foreign metal ions.	Nitrogen	88-96	lysine acetyltransferase 8	Homo sapiens	12-41
16331812-10	2005	(4) The concentrations of urea nitrogen and creatinine in cyst fluid of E15 and E16 metanephroi were increased 40-fold and 50-fold, which were comparable to those in bladder urine.	Nitrogen	31-39	solute carrier family 7 member 5	Rattus norvegicus	80-83
25454438-3	2015	The Brunauer, Emmett and Teller (BET) surface area of TiSis obtained from pure and technical precursors measured using the low-temperature nitrogen adsorption/desorption technique were 270.3 and 158.7 m(2) g(-1), respectively.	Nitrogen	139-147	delta/notch like EGF repeat containing	Homo sapiens	33-36
16046406-6	2005	In this study, we used a more subtle N-linked glycosylation scanning approach, which allowed us to assess the topology of functional PS1 molecules.	Nitrogen	37-38	presenilin 1	Homo sapiens	133-136
16834283-0	2005	Theoretical study of the mechanism of hydrogenation of side-on coordinated dinitrogen activated by Zr binuclear complexes ([(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2)).	Nitrogen	75-85	DNA polymerase iota	Homo sapiens	147-151
16834283-0	2005	Theoretical study of the mechanism of hydrogenation of side-on coordinated dinitrogen activated by Zr binuclear complexes ([(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2)).	Nitrogen	75-85	DNA polymerase iota	Homo sapiens	152-156
25434570-5	2015	In addition, Ag-N-TiO2-YSM shows enhanced activity compared with N-TiO2-YSM due to the SPR absorption of silver NPs and the fast generation, separation and transportation of the photogenerated carriers.	Nitrogen	16-17	sepiapterin reductase	Homo sapiens	87-90
16024031-2	2005	Aggregation of primary particles and adsorption capacity (Vp) decrease and hysteresis loops of nitrogen adsorption-desorption isotherms becomes shorter with decreasing specific surface area (S(BET)).	Nitrogen	95-103	delta/notch like EGF repeat containing	Homo sapiens	193-196
16024031-3	2005	However, the shape of nitrogen adsorption-desorption isotherms can be assigned to the same type independent of S(BET) value.	Nitrogen	22-30	delta/notch like EGF repeat containing	Homo sapiens	113-116
25559887-10	2015	Additionally, cardioprotection by n-3 TG emulsion was linked to changes in PPARgamma protein expression (p&lt;0.05).	Nitrogen	7-8	peroxisome proliferator activated receptor gamma	Mus musculus	75-84
15919744-6	2005	The effect of both central and peripheral N/OFQ was blocked by functional ablation of afferent nerves produced by capsaicin, by the antagonist of calcitonin gene-related peptide, CGRP(8-37), and by the nitric oxide synthase inhibitor, N(G)-nitro-L-arginine methyl ester.	Nitrogen	42-43	calcitonin-related polypeptide alpha	Rattus norvegicus	179-183
15804238-0	2005	Topology of transmembrane segments 1-4 in the human chloride/bicarbonate anion exchanger 1 (AE1) by scanning N-glycosylation mutagenesis.	Nitrogen	109-110	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	73-90
15804238-0	2005	Topology of transmembrane segments 1-4 in the human chloride/bicarbonate anion exchanger 1 (AE1) by scanning N-glycosylation mutagenesis.	Nitrogen	109-110	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	92-95
15804238-7	2005	These results suggest that the TM2-3 region of AE1 may become transiently exposed to the endoplasmic reticulum lumen during biosynthesis, and that there is a competition between proper folding of the region into the membrane and N-glycosylation at introduced sites.	Nitrogen	229-230	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	47-50
15804238-9	2005	As a result, engineered N-glycosylation acceptor sites in TM2-3 could not be utilized by the oligosaccharyltransferase in this mutant form of AE1.	Nitrogen	24-25	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	142-145
25863209-3	2015	After 114days of operation, the STF-1 had an average NH4(+)-N removal of 69.3% (1.17kgN/m(3)sponged) and a total nitrogen removal of 52.2% (0.88kgN/m(3)sponged) at a Nitrogen Loading Rate (NLR) of 1.68kgN/m(3)sponged and Hydraulic Retention Time (HRT) of 1.71h.	Nitrogen	56-61	pancreatic and duodenal homeobox 1	Homo sapiens	32-37
15950943-1	2005	The Prnd-encoded prion protein (PrP)-like protein, Doppel (Dpl), is a homologue of Prnp-encoded PrP, and is N-glycosylated protein with glycosylphosphatidylinositol anchor like PrP.	Nitrogen	108-109	prion protein	Mus musculus	83-87
15950943-1	2005	The Prnd-encoded prion protein (PrP)-like protein, Doppel (Dpl), is a homologue of Prnp-encoded PrP, and is N-glycosylated protein with glycosylphosphatidylinositol anchor like PrP.	Nitrogen	108-109	prion protein	Mus musculus	96-99
15950943-1	2005	The Prnd-encoded prion protein (PrP)-like protein, Doppel (Dpl), is a homologue of Prnp-encoded PrP, and is N-glycosylated protein with glycosylphosphatidylinositol anchor like PrP.	Nitrogen	108-109	prion protein	Mus musculus	96-99
25863209-3	2015	After 114days of operation, the STF-1 had an average NH4(+)-N removal of 69.3% (1.17kgN/m(3)sponged) and a total nitrogen removal of 52.2% (0.88kgN/m(3)sponged) at a Nitrogen Loading Rate (NLR) of 1.68kgN/m(3)sponged and Hydraulic Retention Time (HRT) of 1.71h.	Nitrogen	113-121	pancreatic and duodenal homeobox 1	Homo sapiens	32-37
25863209-3	2015	After 114days of operation, the STF-1 had an average NH4(+)-N removal of 69.3% (1.17kgN/m(3)sponged) and a total nitrogen removal of 52.2% (0.88kgN/m(3)sponged) at a Nitrogen Loading Rate (NLR) of 1.68kgN/m(3)sponged and Hydraulic Retention Time (HRT) of 1.71h.	Nitrogen	166-174	pancreatic and duodenal homeobox 1	Homo sapiens	32-37
26265923-5	2015	Administration of Cyp resulted in a significant increase in serum marker enzymes, for example, aminotransferases (AST and ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT), and increases the level of urea nitrogen and creatinine.	Nitrogen	226-234	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	18-21
16088873-2	2005	The basis of positive selection for cytosine deaminase (Fcy1) activity is that (a) fcy1 strains are unable to grow on medium containing cytosine as a sole nitrogen source and (b) fcy1 ura3 strains are unable to grow on medium containing cytosine as the sole pyrimidine source.	Nitrogen	155-163	cytosine deaminase	Saccharomyces cerevisiae S288C	56-60
15998031-3	2005	The reaction of [NHEt3]2 with NEt3 resulted in the formation of [NHEt3]+ [(C6F5)3BOH]-, [NHEt3]+ [(C6F5)3BH]-, and (C6F5)3B- (CH2CH=N+ Et2).	Nitrogen	17-18	tetraspanin 2	Homo sapiens	30-34
26577736-5	2015	We describe a roadmap to produce isotopically labeled (15)N and (13)C posttranslationally modified proteins, such as the outer domain of HIV-1 gp120, which has four disulfide bonds and 15 potential sites of N-linked glycosylation.	Nitrogen	58-59	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	143-148
15864798-5	2005	X-ray crystallography was performed on the PF6- salt of 2 a, and showed that the deprotonated nitrogen atom on the carbamoyl group coordinates to the ruthenium(II) metal center with a bond length of 2.086(3) Angstroms.	Nitrogen	94-102	sperm associated antigen 17	Homo sapiens	43-46
15931076-0	2005	Characterization of rat transient receptor potential vanilloid 1 receptors lacking the N-glycosylation site N604.	Nitrogen	87-88	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	24-64
26169738-6	2015	The protocol is exemplarily demonstrated for N-glycosylation fingerprinting of cell culture-derived influenza A and B viruses and their major antigens, the membrane glycoproteins hemagglutinin and neuraminidase.	Nitrogen	45-46	neuraminidase 1	Homo sapiens	197-210
15931076-4	2005	Hence, glycosylation may affect the basic functional characteristics of the rTRPV1 receptor channel in accordance with the knowledge that N-glycosylation may regulate ligand binding or gating properties of ionotropic neurotransmitter receptors.	Nitrogen	138-139	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	76-82
15686448-0	2005	Arabidopsis thaliana beta1,2-xylosyltransferase: an unusual glycosyltransferase with the potential to act at multiple stages of the plant N-glycosylation pathway.	Nitrogen	138-139	glycosyltransferase	Arabidopsis thaliana	60-79
25349282-9	2015	We further traced QTLs down to single-nucleotide resolution and uncovered loss-of-function mutations in RIM15, PUT4, DAL1, and DAL4 as the genetic basis for nitrogen source use variations.	Nitrogen	157-165	proline permease PUT4	Saccharomyces cerevisiae S288C	111-115
25219669-7	2015	Both molecules were able to induce Insulin Growth Factor-I (IGF-I) and to stimulate SOX-9, whereas NAPA and G + N were able to up-regulate both Hyaluronic Acid Synthase-2 and Hyaluronic acid.	Nitrogen	99-100	hyaluronan synthase 2	Homo sapiens	144-170
15913380-0	2005	Dinitrogen functionalization with terminal alkynes, amines, and hydrazines promoted by [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2): observation of side-on and end-on diazenido complexes in the reduction of N2 to hydrazine.	Nitrogen	121-123	DNA polymerase iota	Homo sapiens	116-120
15913380-1	2005	Functionalization of the N2 ligand in the side-on bound dinitrogen complex, [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2), has been accomplished by addition of terminal alkynes to furnish acetylide zirconocene diazenido complexes, [(eta5-C5Me4H)2Zr(C[triple bond]CR)]2(mu2,eta2,eta2-N2H2) (R = nBu, tBu, Ph).	Nitrogen	56-66	DNA polymerase iota	Homo sapiens	100-104
15913380-1	2005	Functionalization of the N2 ligand in the side-on bound dinitrogen complex, [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2), has been accomplished by addition of terminal alkynes to furnish acetylide zirconocene diazenido complexes, [(eta5-C5Me4H)2Zr(C[triple bond]CR)]2(mu2,eta2,eta2-N2H2) (R = nBu, tBu, Ph).	Nitrogen	56-66	DNA polymerase iota	Homo sapiens	105-109
15913380-1	2005	Functionalization of the N2 ligand in the side-on bound dinitrogen complex, [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2), has been accomplished by addition of terminal alkynes to furnish acetylide zirconocene diazenido complexes, [(eta5-C5Me4H)2Zr(C[triple bond]CR)]2(mu2,eta2,eta2-N2H2) (R = nBu, tBu, Ph).	Nitrogen	56-66	DNA polymerase iota	Homo sapiens	105-109
15913380-1	2005	Functionalization of the N2 ligand in the side-on bound dinitrogen complex, [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2), has been accomplished by addition of terminal alkynes to furnish acetylide zirconocene diazenido complexes, [(eta5-C5Me4H)2Zr(C[triple bond]CR)]2(mu2,eta2,eta2-N2H2) (R = nBu, tBu, Ph).	Nitrogen	56-66	DNA polymerase iota	Homo sapiens	105-109
26259534-0	2015	Premature termination of GAT1 transcription explains paradoxical negative correlation between nitrogen-responsive mRNA, but constitutive low-level protein production.	Nitrogen	94-102	Gat1p	Saccharomyces cerevisiae S288C	25-29
15840646-2	2005	In mature flag leaves, large amounts of GS1 were detected in the connections between the mestome sheath cells and the vascular cells, suggesting an active transfer of nitrogen organic molecules within the vascular system in the mature flag leaf.	Nitrogen	167-175	glutathione synthetase, chloroplastic	Triticum aestivum	40-43
15952393-5	2005	Nitrogen adsorption-desorption analyses showed the BET specific surface area, total pore volume, porosity, and average mesoporous diameter all decreased with iron impregnation, indicating that some micropores were blocked.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	51-54
15604092-2	2005	The glycan structures of the porcine ZP and the complete N-glycosylation pattern of the ZPB/ZPC oligomer has been recently described.	Nitrogen	57-58	zona pellucida glycoprotein 3	Homo sapiens	92-95
15604092-3	2005	Here we report the N-glycan pattern and N-glycosylation sites of the porcine ZP glycoprotein ZPA of an immature oocyte population as determined by a mass spectrometric approach.	Nitrogen	19-20	zona pellucida glycoprotein 2	Homo sapiens	93-96
26259534-4	2015	In this paper, we show that the GAT1 gene, encoding a transcriptional activator of nitrogen-responsive catabolic genes, produces a variety of mRNAs differing in their 5" and 3" termini.	Nitrogen	83-91	Gat1p	Saccharomyces cerevisiae S288C	32-36
25350608-5	2014	TGA data showed that the postpolymerized polymer had a 5 wt % loss temperature at 495  C and a residual of 61% at 1000  C under N2.	Nitrogen	128-130	T-box transcription factor 1	Homo sapiens	0-3
15833342-7	2005	At high pH values, the further deprotonation of the N-H imidazole group, leading to the formation of MLH(-3), occurs, as revealed by 1H NMR spectroscopy.	Nitrogen	52-53	mutL homolog 3	Homo sapiens	101-107
25284379-4	2014	Reaction of 1 with PhN=C=O (2 equiv) led to the migration of SiMe3 to the amido nitrogen atom to give complex (BODDI)Lu2 (CH2 SiMe3 )2 -mu-{PhNC(O)CHC(O)NPh(SiMe3 )-kappa(3) N,O,O}(THF) (5).	Nitrogen	80-88	carbamoyl-phosphate synthase 1	Homo sapiens	19-22
15952736-4	2005	Partial sequencing identified this protein as afamin, a previously described member of the albumin gene family with four or five potential N-glycosylation sites.	Nitrogen	139-140	afamin	Homo sapiens	46-52
25432047-1	2014	We present the discovery of a novel nitrogen phase synthesized using laser-heated diamond anvil cells at pressures between 120-180 GPa well above the stability field of cubic gauche (cg)-N.	Nitrogen	36-44	cingulin	Homo sapiens	169-188
15723833-6	2005	The mutated bovine LHbeta-boCTP subunit was expressed and N-glycosylated in transfected Chinese hamster ovary cells.	Nitrogen	58-59	lutropin subunit beta	Bos taurus	19-25
25092234-10	2014	These data provide valuable structural information useful to understand the potential roles of N-glycosylation on hFXI function and could serve as a structural reference.	Nitrogen	95-96	coagulation factor XI	Homo sapiens	114-118
15806612-4	2005	This complex formation correlates with Gln3 being sequestered in the cytoplasm under conditions of excess nitrogen, where Gln3/Gat1-mediated transcription is minimal.	Nitrogen	106-114	Gat1p	Saccharomyces cerevisiae S288C	127-131
15822986-4	2005	Specifically, a diester cryptand with a pyridyl nitrogen atom located at a site occupied by either water or a PF(6) anion in analogous complexes exhibited the highest association constant K(a) = 5.0 x 10(6) M(-1) in acetone with paraquat, 9000 times greater than the crown ether system.	Nitrogen	48-56	sperm associated antigen 17	Homo sapiens	110-115
25151579-0	2014	Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3beta (GSK-3beta) phosphorylation inhibitors.	Nitrogen	47-48	cyclin dependent kinase 2	Homo sapiens	115-140
15752017-8	2005	The implications of the new theory for the accuracy of nitrogen adsorption BET surface areas for silicas are discussed.	Nitrogen	55-63	delta/notch like EGF repeat containing	Homo sapiens	75-78
15383589-8	2004	IL4I1 is N-linked glycosylated, a requirement for lysosomal localization.	Nitrogen	9-10	interleukin 4 induced 1	Homo sapiens	0-5
25151579-0	2014	Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3beta (GSK-3beta) phosphorylation inhibitors.	Nitrogen	47-48	cyclin dependent kinase 2	Homo sapiens	142-146
25151579-0	2014	Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3beta (GSK-3beta) phosphorylation inhibitors.	Nitrogen	47-48	glycogen synthase kinase 3 beta	Homo sapiens	148-178
15317460-3	2004	In addition, this library probed the PNMT active site surrounding the sulfonamide nitrogen of 7.	Nitrogen	82-90	phenylethanolamine N-methyltransferase	Homo sapiens	37-41
15317460-4	2004	Bulky substituents on the sulfonamide nitrogen are disfavored at the PNMT active site more so than at the alpha2-adrenoceptor (thus reducing selectivity).	Nitrogen	38-46	phenylethanolamine N-methyltransferase	Homo sapiens	69-73
25151579-0	2014	Design, synthesis and biological evaluation of N-alkyl or aryl substituted isoindigo derivatives as potential dual cyclin-dependent kinase 2 (CDK2)/glycogen synthase kinase 3beta (GSK-3beta) phosphorylation inhibitors.	Nitrogen	47-48	glycogen synthase kinase 3 beta	Homo sapiens	180-189
15317460-5	2004	On the other hand, alkyl chains on the sulfonamide nitrogen that contain an electron dense atom, such as a fluorine, are favored in the PNMT active site and possess little alpha2-adrenoceptor affinity, thereby conferring good selectivity (&gt;500).	Nitrogen	51-59	phenylethanolamine N-methyltransferase	Homo sapiens	136-140
15787366-4	2005	BET nitrogen adsorption and mercury porosimetry were used to evaluate pore structure, and the results suggest that a decrease in contact angle was likely to be responsible for improved mercury capture over time.	Nitrogen	4-12	delta/notch like EGF repeat containing	Homo sapiens	0-3
25065551-3	2014	In this study, we show that Arabidopsis NITRATE TRANSPORTER 2.5 (NRT2.5) is a plasma membrane-localized high-affinity nitrate transporter playing an essential role in adult plants under severe nitrogen starvation.	Nitrogen	193-201	nitrate transporter2.5	Arabidopsis thaliana	40-63
25065551-8	2014	Growth analyses of multiple mutants between NRT2.1, NRT2.2, NRT2.4, and NRT2.5 revealed that NRT2.5 is required to support growth of nitrogen-starved adult plants by ensuring the efficient uptake of nitrate collectively with NRT2.1, NRT2.2 and NRT2.4 and by taking part in nitrate loading into the phloem during nitrate remobilization.	Nitrogen	133-141	nitrate transporter2.5	Arabidopsis thaliana	72-78
15752204-0	2005	Unique mechanistic features of post-translational regulation of glutamine synthetase activity in Methanosarcina mazei strain Go1 in response to nitrogen availability.	Nitrogen	144-152	glutamine synthetase family protein	Methanosarcina mazei Go1	64-84
15278153-1	2004	FAU-type zeolite membranes were synthesized by the vapor phase transformation (VPT) methods with or without prior seeding on the substrate, and it was revealed that the CO(2)/N(2) selectivity of the seeded membrane is greater than that of the unseeded membrane.	Nitrogen	175-179	FAU ubiquitin like and ribosomal protein S30 fusion	Homo sapiens	0-3
15752204-7	2005	On the basis of these findings, we hypothesize that besides the dominant effector molecule 2-oxoglutarate, the nitrogen sensor GlnK(1) allows finetuning control of the glutamine synthetase activity under changing nitrogen availabilities and propose the following model.	Nitrogen	111-119	glutamine synthetase family protein	Methanosarcina mazei Go1	168-188
15752204-7	2005	On the basis of these findings, we hypothesize that besides the dominant effector molecule 2-oxoglutarate, the nitrogen sensor GlnK(1) allows finetuning control of the glutamine synthetase activity under changing nitrogen availabilities and propose the following model.	Nitrogen	213-221	glutamine synthetase family protein	Methanosarcina mazei Go1	168-188
15686361-0	2005	P(450)/NADPH/O(2)- and P(450)/PhIO-catalyzed N-dealkylations are mechanistically distinct.	Nitrogen	7-8	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-6
15310245-7	2004	UGT1A1 was the most efficient in converting N-hydroxy-PhIP to both conjugates producing five times more of the N(2)-conjugate than UGT1A4, the next most active UGT, and 286 times more than UGT1A7, the least active UGT.	Nitrogen	111-115	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	0-3
15253935-5	2004	In addition, we showed that N and eyg could induce expression of upd, which encodes the ligand for the Jak/STAT pathway and acts over long distance to promote cell proliferation.	Nitrogen	28-29	unpaired 1	Drosophila melanogaster	65-68
25162936-1	2014	Pyridoxal 5"-phosphate (PLP) Schiff base, a versatile cofactor, exhibits a tautomeric equilibrium that involves an intramolecular proton transfer between the N-protonated zwitterionic ketoenamine tautomer and the O-protonated covalent enolimine tautomer.	Nitrogen	158-159	pyridoxal phosphatase	Homo sapiens	0-22
15576089-3	2005	N2 adsorption isotherms at 77 K were investigated by BET and t-plot methods to characterize the specific surface areas and pore volumes, and NO removal efficiency was confirmed by a gas chromatographic technique.	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	53-56
25162936-1	2014	Pyridoxal 5"-phosphate (PLP) Schiff base, a versatile cofactor, exhibits a tautomeric equilibrium that involves an intramolecular proton transfer between the N-protonated zwitterionic ketoenamine tautomer and the O-protonated covalent enolimine tautomer.	Nitrogen	158-159	pyridoxal phosphatase	Homo sapiens	24-27
15194452-4	2004	The ET(B)-deficient sl/sl rats exhibited earlier and higher increases in systolic blood pressure, urinary protein excretion, blood urea nitrogen and plasma creatinine concentration, compared with cases in wild-type rats.	Nitrogen	136-144	endothelin receptor type B	Rattus norvegicus	4-9
24881047-2	2014	Dsd1p uses the Tyr residue (Y203) to interact with the pyridine nitrogen of PLP, which is a unique feature of PLP enzymes.	Nitrogen	64-72	D-serine ammonia-lyase DSD1	Saccharomyces cerevisiae S288C	0-5
15178258-5	2004	Furthermore, N-H residual dipolar couplings provided direct evidence for the existence of native-like hydrophobic interactions in the acid-denatured state of ACBP at pH 2.3.	Nitrogen	13-14	diazepam binding inhibitor, acyl-CoA binding protein	Bos taurus	158-162
15642744-6	2005	The role of individual FcepsilonRI subunits for the formation of functional, immunoglobulin E-binding FcepsilonRI complexes during endoplasmic reticulum (ER) assembly can be defined as follows: beta and gamma support ER insertion, signal peptide cleavage and proper N-glycosylation of alpha, whereas beta(var) allows accumulation of alpha protein backbone.	Nitrogen	266-267	Fc epsilon receptor Ia	Homo sapiens	23-34
15642744-6	2005	The role of individual FcepsilonRI subunits for the formation of functional, immunoglobulin E-binding FcepsilonRI complexes during endoplasmic reticulum (ER) assembly can be defined as follows: beta and gamma support ER insertion, signal peptide cleavage and proper N-glycosylation of alpha, whereas beta(var) allows accumulation of alpha protein backbone.	Nitrogen	266-267	Fc epsilon receptor Ia	Homo sapiens	102-113
15478002-5	2005	The results of these studies revealed that the inhibition of either N-linked glycosylation or oligosaccharide synthesis for GPI-anchor addition could affect the synthesis and the distribution of sALP, but not the kinetics of the phosphatase reaction.	Nitrogen	68-69	glucose-6-phosphate isomerase	Homo sapiens	124-127
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	mucin 1, cell surface associated	Homo sapiens	28-32
14693668-9	2004	Also based on the tissue nitrotyrosine staining, the reactive oxygen and nitrogen intermediates seemed to be reduced in tissue in CD40KO mice.	Nitrogen	73-81	CD40 antigen	Mus musculus	130-136
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	mucin 1, cell surface associated	Homo sapiens	158-162
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	galectin 3	Homo sapiens	165-175
15355968-9	2004	ADAMTS10 expressed in HEK293F and COS-1 cells is N-glycosylated and is secreted into the medium, as well as sequestered at the cell surface and extracellular matrix, as demonstrated by cell surface biotinylation and immunolocalization in nonpermeabilized cells.	Nitrogen	49-50	ADAM metallopeptidase with thrombospondin type 1 motif 10	Homo sapiens	0-8
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	mucin 1, cell surface associated	Homo sapiens	158-162
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	mucin 1, cell surface associated	Homo sapiens	158-162
15146521-5	2004	However, a comparison of the thermodynamic reaction profiles for catalytic model cycles of dihydroxylation, aminohydroxylation, and diamination reveals that, contrary to common belief, the instability of the metal=N bond in the osmium(VIII) imido complex rather than the stability of the metal-N bond in the osmium(VI) intermediate causes most of the energy difference between the metallacycles.	Nitrogen	214-215	cytochrome c oxidase subunit 8A	Homo sapiens	235-239
24838315-9	2014	Chemical deglycosylation of MUC1 using a mixture of N-glycosylation inhibitor tunicamycin and O-glycosylation inhibitor benzyl-alpha-GalNAc disrupted the Src/MUC1-C/galectin-3/EGFR complexes and thereby abolished smoke-induced MUC1-C-TyrP and MUC1-C/p120ctn interaction.	Nitrogen	52-53	catenin delta 1	Homo sapiens	250-257
24803501-9	2014	The metabolic response of N-replete transgenic plants overlapped with that of N-stressed wild types, as the majority of phenylpropanoid derivatives significantly affected by GT1-316 overexpression were also significantly changed by N stress in the wild types.	Nitrogen	26-27	myosin light chain 4	Homo sapiens	174-177
15144224-6	2004	These data indicate that (i) human P450 1A1 and 1B1 differ dramatically with respect to the regiospecific metabolism of DB[a,h]ACR, (ii) human P450 1A1 is substantially more active than human P450 1B1 in the metabolic activation of the aza-PAH to its 10,11-diol, and (iii) the presence of nitrogen influences the relative extent to which the two benzo ring diols with a bay region double bond are formed by human P450s 1A1 and 1B1.	Nitrogen	289-297	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	35-51
15144224-6	2004	These data indicate that (i) human P450 1A1 and 1B1 differ dramatically with respect to the regiospecific metabolism of DB[a,h]ACR, (ii) human P450 1A1 is substantially more active than human P450 1B1 in the metabolic activation of the aza-PAH to its 10,11-diol, and (iii) the presence of nitrogen influences the relative extent to which the two benzo ring diols with a bay region double bond are formed by human P450s 1A1 and 1B1.	Nitrogen	289-297	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	192-200
15144224-6	2004	These data indicate that (i) human P450 1A1 and 1B1 differ dramatically with respect to the regiospecific metabolism of DB[a,h]ACR, (ii) human P450 1A1 is substantially more active than human P450 1B1 in the metabolic activation of the aza-PAH to its 10,11-diol, and (iii) the presence of nitrogen influences the relative extent to which the two benzo ring diols with a bay region double bond are formed by human P450s 1A1 and 1B1.	Nitrogen	289-297	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	413-430
15051435-4	2004	The decrease in BET surface area of montmorillonites after adsorption of dyes was interpreted in terms of both the coverage of some surface roughness (surface screening effect) and the inhibition of the movement of nitrogen molecule into some pores (pore blocking effect).	Nitrogen	215-223	delta/notch like EGF repeat containing	Homo sapiens	16-19
15815077-9	2004	Based on these data, we conclude that EtOH-inducible microsomal CYP isoforms (mainly CYP2E1) are responsible for binding and N-demethylation metabolism of both studied N-nitrosamines in rabbit liver microsomal system.	Nitrogen	125-126	cytochrome P-450	Oryctolagus cuniculus	64-67
15662545-0	2004	The effect of nitrogen source on yield and glycosylation of a human cystatin C mutant expressed in Pichia pastoris.	Nitrogen	14-22	cystatin C	Homo sapiens	68-78
15662545-7	2004	Little of the cystatin C produced was in the glycosylated form under fermentation conditions of pH 6, temperature 28 degrees C, methanol only feed, and ammonium hydroxide as a nitrogen source.	Nitrogen	176-184	cystatin C	Homo sapiens	14-24
15662545-11	2004	A maximum mutant cystatin C yield of 0.82 mumol (g-dry cell weight)(-1) min(-1) was obtained when all three nitrogen sources were used together.	Nitrogen	108-116	cystatin C	Homo sapiens	17-27
15521731-1	2004	The origin of the hydrogenation of the dinitrogen ligand in [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2) has been investigated by a combined computational and experimental study.	Nitrogen	39-49	DNA polymerase iota	Homo sapiens	84-88
15521731-1	2004	The origin of the hydrogenation of the dinitrogen ligand in [(eta5-C5Me4H)2Zr]2(mu2,eta2,eta2-N2) has been investigated by a combined computational and experimental study.	Nitrogen	39-49	DNA polymerase iota	Homo sapiens	89-93
15521731-3	2004	The twisted ground-state structure of the N2 complex is a key requirement for nitrogen hydrogenation, as calculations on the model complex [(eta5-C5H5)2Zr]2(mu2,eta2,eta2-N2) reveal reduced overlap as the dihedral angle between the zirconocene wedges approaches 0 degrees .	Nitrogen	42-44	DNA polymerase iota	Homo sapiens	161-165
15521731-3	2004	The twisted ground-state structure of the N2 complex is a key requirement for nitrogen hydrogenation, as calculations on the model complex [(eta5-C5H5)2Zr]2(mu2,eta2,eta2-N2) reveal reduced overlap as the dihedral angle between the zirconocene wedges approaches 0 degrees .	Nitrogen	42-44	DNA polymerase iota	Homo sapiens	166-170
15048820-9	2004	Two stable water molecules in the trajectory of the free CDK2 were found that occupy the same position as the nitrogens N3 and N9 of the isopentenyladenine or N1 and N6 nitrogens of the adenosine triphosphate (ATP).	Nitrogen	110-119	cyclin dependent kinase 2	Homo sapiens	57-61
25033834-4	2014	APE1/Ref-1 maintains cellular homeostasis (redox) via the activation of TFs that regulate various physiological processes and that crosstalk with redox balancing agents (for example, thioredoxin, catalase and superoxide dismutase) by controlling levels of reactive oxygen and nitrogen species.	Nitrogen	276-284	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	0-4
15048820-9	2004	Two stable water molecules in the trajectory of the free CDK2 were found that occupy the same position as the nitrogens N3 and N9 of the isopentenyladenine or N1 and N6 nitrogens of the adenosine triphosphate (ATP).	Nitrogen	169-178	cyclin dependent kinase 2	Homo sapiens	57-61
15521731-3	2004	The twisted ground-state structure of the N2 complex is a key requirement for nitrogen hydrogenation, as calculations on the model complex [(eta5-C5H5)2Zr]2(mu2,eta2,eta2-N2) reveal reduced overlap as the dihedral angle between the zirconocene wedges approaches 0 degrees .	Nitrogen	78-86	DNA polymerase iota	Homo sapiens	166-170
16701529-7	2004	A total of 97-99% dinitrotoluene removal efficiencies in the reactors containing COD to NO(3)-N ratio of 2 and 3.75 after 20 days of incubation period.	Nitrogen	88-89	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	81-84
25033834-4	2014	APE1/Ref-1 maintains cellular homeostasis (redox) via the activation of TFs that regulate various physiological processes and that crosstalk with redox balancing agents (for example, thioredoxin, catalase and superoxide dismutase) by controlling levels of reactive oxygen and nitrogen species.	Nitrogen	276-284	apurinic/apyrimidinic endodeoxyribonuclease 1	Homo sapiens	5-10
24837348-4	2014	RESULTS: In multivariable Cox proportional hazards regression analysis, NT-proBNP or BNP levels in the upper 50th percentile were the strongest predictor of ICD therapy after adjustment for sex, age, left ventricular ejection fraction, New York Heart Association class, history of coronary artery disease, blood urea nitrogen, creatinine clearance, and history of atrial fibrillation (hazard ratio [HR] 5.75, P &lt; .001 for NT-proBNP; HR 3.40, P = .01 for BNP).	Nitrogen	317-325	natriuretic peptide B	Homo sapiens	85-88
15542540-1	2004	In an attempt to design immunogens that elicit broadly HIV-neutralizing antibodies, we recently engineered monomeric HIV-1 gp120 to bind preferentially b12, a broadly neutralizing antibody to the CD4-binding site (CD4bs) on gp120, by mutating four central residues in the CD4bs to alanine and introducing extra N-glycosylation sites potentially to mask unwanted B-cell epitopes.	Nitrogen	311-312	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	123-128
15971617-6	2004	Peptone was shown to be a favorable nitrogen source for catalase production and its optimum concentration was found to be 10 g/L.	Nitrogen	36-44	catalase	Bos taurus	56-64
14970212-0	2004	The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.	Nitrogen	24-25	amyloid beta precursor like protein 2	Homo sapiens	91-97
14757761-8	2004	GLN1;4 was another high affinity-type GS1 expressed in nitrogen-starved plants but was 10-fold less abundant than GLN1;1.	Nitrogen	55-63	glutamine synthetase 1;4	Arabidopsis thaliana	0-6
25493288-4	2014	GPR126 possesses a signal peptide, a 7TM domain homologous to secretin-like GPCRs, a GPS motif and an extended N-terminus containing a CUB (Complement, Uegf, Bmp1) domain, a PTX (Pentraxin) domain, a hormone binding domain and 27 putative N-glycosylation sites.	Nitrogen	111-112	adhesion G protein-coupled receptor G6	Homo sapiens	0-6
15514753-1	2004	Preparations of novel unsymmetrical, tridentate nitrogen ligand precursors, PhN=C(CMe2)(NPh)C=N(CH2)2NMe2(1) and PhN=C(CMe2)(NPh)C=N(CH2)Py (2), are described.	Nitrogen	48-56	carbamoyl-phosphate synthase 1	Homo sapiens	76-79
15514753-1	2004	Preparations of novel unsymmetrical, tridentate nitrogen ligand precursors, PhN=C(CMe2)(NPh)C=N(CH2)2NMe2(1) and PhN=C(CMe2)(NPh)C=N(CH2)Py (2), are described.	Nitrogen	48-56	carbamoyl-phosphate synthase 1	Homo sapiens	113-116
15247235-1	2004	The GATA transcription factors GLN3 and GAT1 activate nitrogen-regulated genes in Saccharomyces cerevisiae.	Nitrogen	54-62	Gat1p	Saccharomyces cerevisiae S288C	40-44
14742717-1	2004	In pancreatic beta-cells, the syntaxin 6 (Syn6) soluble N-ethylmaleimide-sensitive factor attachment protein receptor is distributed in the trans-Golgi network (TGN) (with spillover into immature secretory granules) and endosomes.	Nitrogen	56-57	syntaxin 6	Rattus norvegicus	30-40
14742717-1	2004	In pancreatic beta-cells, the syntaxin 6 (Syn6) soluble N-ethylmaleimide-sensitive factor attachment protein receptor is distributed in the trans-Golgi network (TGN) (with spillover into immature secretory granules) and endosomes.	Nitrogen	56-57	syntaxin 6	Rattus norvegicus	42-46
24806741-2	2014	These APN (atropos P,N) ligands require a specific type of biaryl, with one component carrying a pendant phosphine unit, most commonly diaryl substituted, and the other bearing an sp(2)-nitrogen adjacent to the biaryl link.	Nitrogen	186-194	alanyl aminopeptidase, membrane	Homo sapiens	6-9
15228154-8	2004	MDMA metabolism is rather complex and includes 2 main metabolic pathways: (1) O-demethylenation followed by catechol-O-methyltransferase (COMT)-catalyzed methylation and/or glucuronide/sulfate conjugation; and (2) N-dealkylation, deamination, and oxidation to the corresponding benzoic acid derivatives conjugated with glycine.	Nitrogen	214-215	catechol-O-methyltransferase	Homo sapiens	138-142
15319333-0	2004	CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.	Nitrogen	61-62	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-6
24806741-2	2014	These APN (atropos P,N) ligands require a specific type of biaryl, with one component carrying a pendant phosphine unit, most commonly diaryl substituted, and the other bearing an sp(2)-nitrogen adjacent to the biaryl link.	Nitrogen	186-194	alanyl aminopeptidase, membrane	Homo sapiens	11-22
14648201-3	2004	We found that loss of G1 cyclins, or inactivation of the cyclin-dependent kinase Cdc28p, reduced the activity of glutamate synthase (Glt1p), a key enzyme in nitrogen assimilation.	Nitrogen	157-165	glutamate synthase (NADH)	Saccharomyces cerevisiae S288C	133-138
24602105-8	2014	In addition, when chemically complemented with the C26 aldehyde n-hexacosanal, cyp83a1 mutants can again support appressorium formation.	Nitrogen	1-2	cytochrome P450, family 83, subfamily A, polypeptide 1	Arabidopsis thaliana	79-86
14711516-4	2004	The disulfide linkage pattern and glycoform distribution on each N-glycosylation site of recombinant chicken Thy-1 from both cell lines were determined by a combination of amino-terminal sequencing and mass spectrometry.	Nitrogen	65-66	Thy-1 cell surface antigen	Gallus gallus	109-114
15240565-6	2004	Compared with nontransgenic controls, transgenic mice overexpressing ORP150 subjected to renal I/R displayed a blunted rise of serum creatinine and blood urea nitrogen, and enhanced survival of TAL, consistent with cytoprotection.	Nitrogen	159-167	hypoxia up-regulated 1	Mus musculus	69-75
24722992-0	2014	Phosphorylation of Arabidopsis ubiquitin ligase ATL31 is critical for plant carbon/nitrogen nutrient balance response and controls the stability of 14-3-3 proteins.	Nitrogen	83-91	carbon/nitrogen insensitive 1	Arabidopsis thaliana	48-53
15305215-2	2004	NMR analysis clearly indicated that the 2Dpy-containing tripeptides except the peptide in which AA1, AA3 = Aib, adopt a unique conformation with two intramolecular hydrogen bonds between 2Dpy-NH and a pyridine nitrogen and between AA3-NH and another pyridine nitrogen.	Nitrogen	210-218	AA1	Homo sapiens	96-99
15305215-2	2004	NMR analysis clearly indicated that the 2Dpy-containing tripeptides except the peptide in which AA1, AA3 = Aib, adopt a unique conformation with two intramolecular hydrogen bonds between 2Dpy-NH and a pyridine nitrogen and between AA3-NH and another pyridine nitrogen.	Nitrogen	259-267	AA1	Homo sapiens	96-99
15280541-2	2004	The POMC-derived peptide alpha-melanocyte-stimulating hormone (alphaMSH) is a melanocortin 4 receptor agonist, and its potency in reducing energy intake is strongly increased by N-acetylation.	Nitrogen	178-179	pro-opiomelanocortin-alpha	Mus musculus	4-8
15280541-2	2004	The POMC-derived peptide alpha-melanocyte-stimulating hormone (alphaMSH) is a melanocortin 4 receptor agonist, and its potency in reducing energy intake is strongly increased by N-acetylation.	Nitrogen	178-179	pro-opiomelanocortin-alpha	Mus musculus	25-61
14725455-0	2004	Highly efficient aza-Baylis-Hillman reaction of N-tosylated imines with MVK, acrolein, and phenyl acrylate or alpha-naphthyl acrylate: Lewis base effects and a convenient method to synthesize alpha,beta-unsaturated beta-amino carbonyl compounds.	Nitrogen	48-49	mevalonate kinase	Homo sapiens	72-75
14725455-1	2004	This paper describes several highly efficient aza-Baylis-Hillman reactions of N-tosylated imines with MVK, acrolein, and phenyl acrylate or alpha-naphthyl acrylate in the presence of a Lewis base.	Nitrogen	78-79	mevalonate kinase	Homo sapiens	102-105
15356719-9	2004	The electronic charge distribution in L(4) and L(5) is similar to that found in other terdentate ligands such as terpyridine which have equally poor extraction properties and suggests that the unique properties of L(1) evolve from the presence of two adjacent nitrogen atoms in the triazine rings.	Nitrogen	260-268	ribosomal protein L4	Homo sapiens	38-42
24722992-2	2014	We have previously shown that ubiquitin ligase ATL31 regulates plant growth in response to nutrient balance between carbon and nitrogen (C/N) in Arabidopsis.	Nitrogen	127-135	carbon/nitrogen insensitive 1	Arabidopsis thaliana	47-52
15352021-10	2004	FMO1, the extrahepatic form of the enzyme in man, was shown to be more active in the N-oxygenation of both deprenyl and methamphetamine isomers than FMO3.	Nitrogen	85-86	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	0-4
24722992-3	2014	Subsequent study demonstrated that ATL31 targets 14-3-3 proteins for ubiquitination and modulates the protein abundance in response to C/N-nutrient status.	Nitrogen	137-138	carbon/nitrogen insensitive 1	Arabidopsis thaliana	35-40
24878721-11	2014	Plasma YKL-40 was significantly elevated in H-OSA (55.2 +- 7.9 ng/ml vs. 35.6 +- 4.2 ng/ml in N-OSA, P = 0.02) and had an inverse relationship with FMD (r = -0.52, P = 0.013).	Nitrogen	94-95	chitinase 3 like 1	Homo sapiens	7-13
15208340-7	2004	Aside from the sulphur-specific regulation, the induction of SULTR1;1 and SULTR1;2 high-affinity sulphate transporters by sulphur limitation was dependent on the supply of carbon and nitrogen.	Nitrogen	183-191	sulfate transporter 1;2	Arabidopsis thaliana	74-82
15775054-6	2004	In contrast, when Cu(+) coordinates via the nitrogen of the SNO group, a shortening of the SN bond with lengthening of the NO bond is observed.	Nitrogen	44-52	strawberry notch homolog 1	Homo sapiens	60-63
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	interleukin 9	Homo sapiens	90-93
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	interleukin 9	Homo sapiens	281-284
24886084-0	2014	Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules.	Nitrogen	127-135	stearoyl-ACP desaturase	Glycine max	17-24
15137438-3	2004	The psychrophilic treatment conducted under the average HRT of 2.44 days and the average OLR of 4.2 g COD/l/day showed an average total COD removal of 58% giving effluents more suitable for subsequent biological nitrogen removal.	Nitrogen	212-220	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	102-105
15137438-3	2004	The psychrophilic treatment conducted under the average HRT of 2.44 days and the average OLR of 4.2 g COD/l/day showed an average total COD removal of 58% giving effluents more suitable for subsequent biological nitrogen removal.	Nitrogen	212-220	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	136-139
15137438-6	2004	On the contrary, psychrophilic anaerobic effluents (richer in COD compared to the submesophilic ones) were more suitable for subsequent aerobic-anoxic treatment giving the total N removal of 95 and 92% at 19 and 10 degrees C, respectively.	Nitrogen	178-179	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	62-65
14652022-3	2003	Mutations in the RER2 gene result in defects in growth and protein N-glycosylation.	Nitrogen	67-68	ditrans,polycis-polyprenyl diphosphate synthase	Saccharomyces cerevisiae S288C	17-21
14658918-5	2003	The metal ion (Cd1) sits above the basal plane of three nitrogen atoms, N(1), N(3), and N(4).	Nitrogen	56-64	CD1c molecule	Homo sapiens	15-18
15356331-5	2004	However, under nitrogen-limited conditions, AtIPT3 expression was rapidly induced by NO(3)(-) in the seedlings accompanying the accumulation of cytokinins, whereas AtIPT5 expression was little affected.	Nitrogen	15-23	isopentenyltransferase 3	Arabidopsis thaliana	44-50
15356331-5	2004	However, under nitrogen-limited conditions, AtIPT3 expression was rapidly induced by NO(3)(-) in the seedlings accompanying the accumulation of cytokinins, whereas AtIPT5 expression was little affected.	Nitrogen	15-23	isopentenyltransferase 5	Arabidopsis thaliana	164-170
15356331-7	2004	These results suggest that nitrogen availability differentially regulates expression of AtIPT3 and AtIPT5, and that AtIPT3 is a key determinant of cytokinin biosynthesis in response to rapid changes in the availability of NO(3)(-).	Nitrogen	27-35	isopentenyltransferase 3	Arabidopsis thaliana	88-94
15356331-7	2004	These results suggest that nitrogen availability differentially regulates expression of AtIPT3 and AtIPT5, and that AtIPT3 is a key determinant of cytokinin biosynthesis in response to rapid changes in the availability of NO(3)(-).	Nitrogen	27-35	isopentenyltransferase 5	Arabidopsis thaliana	99-105
15187136-1	2004	Arginase I expression in the liver must remain constant throughout life to eliminate excess nitrogen via the urea cycle.	Nitrogen	92-100	arginase, liver	Mus musculus	0-10
15141165-2	2004	Spliced Hac1p (Hac1ip) is a negative regulator of differentiation responses to nitrogen starvation, pseudohyphal growth, and meiosis.	Nitrogen	79-87	transcription factor HAC1	Saccharomyces cerevisiae S288C	8-13
15141165-6	2004	In summary, nitrogen-induced synthesis of Hac1ip and association of Hac1ip with the HDAC are physiological events in the regulation of EMGs by nutrients.	Nitrogen	12-20	transcription factor HAC1	Saccharomyces cerevisiae S288C	42-46
14659076-4	2003	The open-reading frame of the MRJP1 homologue (AcMRJP1) was 1299 nucleotides that encoded 433 deduced amino acids with three predicted N-linked glycosylation sites.	Nitrogen	135-136	major royal jelly protein 1	Apis cerana	47-54
24652287-7	2014	These studies revealed that Arg-80, Lys-350, and Arg-190 of 2OST interact with the N-sulfo groups near the modification site, consistent with the dependence of 2OST on N-sulfation.	Nitrogen	83-84	heparan sulfate 2-O-sulfotransferase 1	Homo sapiens	60-64
14622291-14	2003	Similar to VR1 the glycosylation is N-linked as shown by an deglycosylation assay.	Nitrogen	36-37	transient receptor potential cation channel, subfamily V, member 1	Rattus norvegicus	11-14
15161308-7	2004	In tetrahydrofuran only N-metalated mixed LiCH(2)CN dimers were observed for both Li-1 and Li-2 with the less shielded (13)C NMR shifts of delta -2.5 and -2.2 for the alpha-carbon of LiCH(2)CN of the complexes.	Nitrogen	24-25	transglutaminase 1	Homo sapiens	82-86
15161308-7	2004	In tetrahydrofuran only N-metalated mixed LiCH(2)CN dimers were observed for both Li-1 and Li-2 with the less shielded (13)C NMR shifts of delta -2.5 and -2.2 for the alpha-carbon of LiCH(2)CN of the complexes.	Nitrogen	24-25	ATP binding cassette subfamily A member 12	Homo sapiens	91-95
24652287-7	2014	These studies revealed that Arg-80, Lys-350, and Arg-190 of 2OST interact with the N-sulfo groups near the modification site, consistent with the dependence of 2OST on N-sulfation.	Nitrogen	83-84	heparan sulfate 2-O-sulfotransferase 1	Homo sapiens	160-164
15154810-3	2004	Reaction of 11 with DABCO (triethylenediamine) resulted in removal of the BH(3) group coordinated to the nitrogen of the side chain, giving 1-(eta(5)-C(5)H(5))-2-NMe(2)(CH(2))(2)-closo-1,2,3,4-FeC(3)B(7)H(9) (12).	Nitrogen	105-113	endothelin receptor type A	Homo sapiens	143-146
24680508-1	2014	A small set of N-bridged 1-deoxynojirimycin dimers has been synthesized and evaluated as potential inhibitors of insect trehalase from midge larvae of Chironomus riparius, porcine trehalase as the mammalian counterpart and alpha-amylase from human saliva.	Nitrogen	15-16	trehalase	Homo sapiens	120-129
15267793-3	2004	The appearance of a signal for the free-NH unit (or weakly bonded N-H...F unit) in the infrared spectrum of the PF(6) (-) salt indicates that conventional N-H...O and N-H...N hydrogen bonds do not fully dominate the packing.	Nitrogen	40-41	sperm associated antigen 17	Homo sapiens	112-117
15267793-3	2004	The appearance of a signal for the free-NH unit (or weakly bonded N-H...F unit) in the infrared spectrum of the PF(6) (-) salt indicates that conventional N-H...O and N-H...N hydrogen bonds do not fully dominate the packing.	Nitrogen	66-67	sperm associated antigen 17	Homo sapiens	112-117
14632661-4	2003	The NA1 allele of CD16B has four asparagine (N)-linked glycosylation sites.	Nitrogen	44-47	Fc gamma receptor IIIb	Homo sapiens	18-23
14622417-0	2003	Candida glabrata STE12 is required for wild-type levels of virulence and nitrogen starvation induced filamentation.	Nitrogen	73-81	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	17-22
14622417-5	2003	Candida glabrata STE12 can functionally complement the nitrogen starvation induced filamentation and mating defects of Saccharomyces cerevisiae ste12 mutants.	Nitrogen	55-63	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	17-22
14622417-5	2003	Candida glabrata STE12 can functionally complement the nitrogen starvation induced filamentation and mating defects of Saccharomyces cerevisiae ste12 mutants.	Nitrogen	55-63	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	144-149
14622417-6	2003	We also show that C. glabrata STE12 is required for nitrogen starvation-induced filamentation as ste12 mutants rarely produce pseudohyphae on nitrogen depleted media.	Nitrogen	52-60	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	30-35
24561278-4	2014	New complexes of palladium (II), with general formulae [Pd(PPh3)2(L)]PF6 or [PdCl(PPh3)(L)], where L=N,N-disubstituted-N"-acyl thioureas, were synthesized and characterized by elemental analysis, molar conductivity, melting points, IR, NMR((1)H, (13)C and (31)P{(1)H}) spectroscopy.	Nitrogen	0-1	sperm associated antigen 17	Homo sapiens	69-72
14622417-6	2003	We also show that C. glabrata STE12 is required for nitrogen starvation-induced filamentation as ste12 mutants rarely produce pseudohyphae on nitrogen depleted media.	Nitrogen	52-60	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	97-102
14622417-6	2003	We also show that C. glabrata STE12 is required for nitrogen starvation-induced filamentation as ste12 mutants rarely produce pseudohyphae on nitrogen depleted media.	Nitrogen	142-150	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	30-35
12933790-6	2003	The recombinant rHARE contained approximately 25 kDa of N-linked oligosaccharides and, like the native protein, was able to bind HA in a ligand blot assay, even after de-N-glycosylation.	Nitrogen	56-57	stabilin 2	Rattus norvegicus	16-21
14559239-0	2003	Gcn4 negatively regulates expression of genes subjected to nitrogen catabolite repression.	Nitrogen	59-67	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	0-4
15047148-4	2004	When N-glycosylation was prevented through point mutations in N-glycosylation sites in CD28, or reduced by glycosidase inhibitors, the binding of CD28 to CD80 significantly increased.	Nitrogen	5-6	CD28 molecule	Homo sapiens	87-91
15047148-4	2004	When N-glycosylation was prevented through point mutations in N-glycosylation sites in CD28, or reduced by glycosidase inhibitors, the binding of CD28 to CD80 significantly increased.	Nitrogen	5-6	CD28 molecule	Homo sapiens	146-150
15047148-4	2004	When N-glycosylation was prevented through point mutations in N-glycosylation sites in CD28, or reduced by glycosidase inhibitors, the binding of CD28 to CD80 significantly increased.	Nitrogen	5-6	CD80 molecule	Homo sapiens	154-158
15047148-4	2004	When N-glycosylation was prevented through point mutations in N-glycosylation sites in CD28, or reduced by glycosidase inhibitors, the binding of CD28 to CD80 significantly increased.	Nitrogen	62-63	CD28 molecule	Homo sapiens	87-91
15047148-4	2004	When N-glycosylation was prevented through point mutations in N-glycosylation sites in CD28, or reduced by glycosidase inhibitors, the binding of CD28 to CD80 significantly increased.	Nitrogen	62-63	CD28 molecule	Homo sapiens	146-150
15063184-6	2004	We provide evidence that both N- and C-terminal Cos2 binding domains are involved in the cytoplasmic retention of Ci155 in imaginal discs.	Nitrogen	30-31	cubitus interruptus	Drosophila melanogaster	114-119
14559239-1	2003	It has been considered that three key elements participate in nitrogen catabolite repression (NCR) of Saccharomyces cerevisiae: the GLN3 and GAT1/NIL1-encoded transcriptional activators and their negative regulator Ure2.	Nitrogen	62-70	Gat1p	Saccharomyces cerevisiae S288C	141-145
14559239-1	2003	It has been considered that three key elements participate in nitrogen catabolite repression (NCR) of Saccharomyces cerevisiae: the GLN3 and GAT1/NIL1-encoded transcriptional activators and their negative regulator Ure2.	Nitrogen	62-70	Gat1p	Saccharomyces cerevisiae S288C	146-150
24678969-1	2014	Nociceptin/OFQ (N/OFQ) is a 17 amino acid peptide that is the endogenous ligand for the ORL1/NOP receptor.	Nitrogen	0-1	opioid related nociceptin receptor 1	Rattus norvegicus	88-92
14594271-1	2003	We present a new synthesis route for nitrogen doped carbon nanotubes (CNx) based on the aerosol method.	Nitrogen	37-45	calnexin	Homo sapiens	70-73
15078194-5	2004	Metabolic activation occurs by N-hydroxylation, a reaction catalyzed by cytochromes p450 (CYP).	Nitrogen	31-32	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	84-88
24673332-2	2014	Herein, the factors governing selective Rh2(esp)2-catalyzed C-H amination of isoamylbenzene derivatives are investigated, where modification to both the nitrogen source, a sulfamate ester, and substrate are shown to impact isomeric product ratios.	Nitrogen	153-161	protein tyrosine phosphatase receptor type V, pseudogene	Homo sapiens	44-47
15016849-0	2004	N-linked glycosylation of the V3 loop and the immunologically silent face of gp120 protects human immunodeficiency virus type 1 SF162 from neutralization by anti-gp120 and anti-gp41 antibodies.	Nitrogen	0-1	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	162-167
14520472-7	2003	NS-398-treated HT-29 cells showed increased p50 homodimer binding and an induction of p50/p65 heterodimers, as demonstrated by supershift assay.	Nitrogen	0-2	RELA proto-oncogene, NF-kB subunit	Homo sapiens	90-93
14517308-7	2003	Thus, TOR may sense optimal nitrogen- and carbon-limiting conditions to modulate Ime1 function.	Nitrogen	28-36	transcription factor IME1	Saccharomyces cerevisiae S288C	81-85
14976351-0	2004	Evaluation of xenobiotic N- and S-oxidation by variant flavin-containing monooxygenase 1 (FMO1) enzymes.	Nitrogen	25-26	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	55-88
24632943-1	2014	With the help of density functional calculations using the HSE and PBE functionals, it is shown that incorporation of nitrogen into ZnO nanoparticles is energetically less costly compared to ZnO bulk, due to charge transfer between Zn dangling bonds and the NO impurity.	Nitrogen	118-126	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	Homo sapiens	67-70
14976351-0	2004	Evaluation of xenobiotic N- and S-oxidation by variant flavin-containing monooxygenase 1 (FMO1) enzymes.	Nitrogen	25-26	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	90-94
12954055-5	2003	To achieve the selectivity at GSK-3beta, the additional nitrogen atoms in the indole rings may contribute to a significant degree.	Nitrogen	56-64	glycogen synthase kinase 3 beta	Homo sapiens	30-39
24164541-1	2014	Aerosolized exposure to the chemical warfare vesicant sulfur mustard and its analog nitrogen mustard (HN2) is known to induce airway lesions associated with secretion of proinflammatory cytokines such as IL-6.	Nitrogen	84-92	MT-RNR2 like 2 (pseudogene)	Homo sapiens	102-105
12927856-6	2003	In addition, the SAR at the 3-amino-2-propanol moiety of 1 suggested that either the nitrogen atom with an electron donating substituent or the unsubstituted nitrogen atom and also the hydroxy group are desirable for elicitation of a potent DAT binding affinity.	Nitrogen	85-93	solute carrier family 6 member 3	Rattus norvegicus	241-244
15025535-3	2004	In this report, we describe a new generation of ICAT reagents that contain the following additional features: (1) a visible tag that allows the electrophoretic position of tagged peptides during separation to be easily monitored; (2) a photocleavable linker that allows most of the tag to be removed prior to mass spectrometric analysis; (3) an isotope tag that contains carbon-13 and nitrogen-15 atoms instead of deuterium to ensure precise comigration of light and heavy tagged peptides by reverse-phase HPLC.	Nitrogen	385-393	catenin beta interacting protein 1	Homo sapiens	48-52
14980636-2	2004	Among the three series of macrocycles, the oxygen atom and thiophene containing linkers yielded molecules with higher inhibitory potency at GSK-3 beta (K(i)=0.011-0.079 microM) while the nitrogen atom containing linkers yielded molecules with lower potency (K(i)=0.150-&gt;1 microM).	Nitrogen	187-195	glycogen synthase kinase 3 beta	Homo sapiens	140-150
24551877-1	2014	High surface area carbon with a nitrogen content of 7.0% is derived from MOF via in situ g-C3N4 formation.	Nitrogen	32-40	lysine acetyltransferase 8	Homo sapiens	73-76
15228008-11	2004	Water stress decreases NR activity, but increases proteinase activity, and thus, they regulate plant nitrogen metabolism, although there are some different effects among species and cultivars.	Nitrogen	101-109	inducible nitrate reductase [NADH] 1	Glycine max	23-25
15228008-17	2004	This paper reviewed the pathway of plant nitrogen assimilation, characteristics of key enzymes and their regulating mechanisms with picturing the regulating mode of NR, and described the signal sensing and conduct of plant nitrogen metabolism and the formation, transportation, storage and degradation of plant cell protein with picturing the schedule of protein transport of membrane system in plant cell.	Nitrogen	41-49	inducible nitrate reductase [NADH] 1	Glycine max	165-167
15228008-17	2004	This paper reviewed the pathway of plant nitrogen assimilation, characteristics of key enzymes and their regulating mechanisms with picturing the regulating mode of NR, and described the signal sensing and conduct of plant nitrogen metabolism and the formation, transportation, storage and degradation of plant cell protein with picturing the schedule of protein transport of membrane system in plant cell.	Nitrogen	223-231	inducible nitrate reductase [NADH] 1	Glycine max	165-167
14533978-8	2004	Nevertheless, this first demonstration of elevated N-BNP in the urine of patients with heart failure raises a number of exciting possibilities with regard to the management of patients with established or possible heart failure.	Nitrogen	0-1	natriuretic peptide B	Homo sapiens	53-56
14734753-4	2004	In contrast, the same cells from TLR2(-/-) still produce TNF-alpha, IL-12, and reactive nitrogen intermediates (RNI) upon exposure to live T. cruzi trypomastigotes.	Nitrogen	88-96	toll-like receptor 2	Mus musculus	33-37
12888891-0	2003	N-glycosylation is required for the surface localization of MUC17 mucin.	Nitrogen	0-1	LOC100508689	Homo sapiens	66-71
12888891-1	2003	The nucleic acid sequence of the human gene, MUC17, indicates that this mucin contains an SEA domain, a transmembrane domain, and putative N-glycosylation sites in the carboxyl terminus.	Nitrogen	139-140	LOC100508689	Homo sapiens	72-77
12895109-0	2003	Theoretical characterization of stable eta1-N2O-, eta2-N2O-, eta1-N2-, and eta2-N2-bound species: intermediates in the addition reactions of nitrogen hydrides with the pentacyanonitrosylferrate(II) ion.	Nitrogen	141-149	DNA polymerase iota	Homo sapiens	50-54
12895109-0	2003	Theoretical characterization of stable eta1-N2O-, eta2-N2O-, eta1-N2-, and eta2-N2-bound species: intermediates in the addition reactions of nitrogen hydrides with the pentacyanonitrosylferrate(II) ion.	Nitrogen	141-149	DNA polymerase iota	Homo sapiens	75-79
12936704-0	2003	Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes.	Nitrogen	92-93	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	29-35
12898651-4	2003	This ion was greatly reduced in the spectra of N,N-dimethyl derivatives, indicating that the [(M + H - glycerol) - Hex](+) ion is formed from an intramolecular rearrangement with migration of the plasmal residue to the free amino group of sphingosine.	Nitrogen	47-48	hematopoietically expressed homeobox	Homo sapiens	115-118
12898651-4	2003	This ion was greatly reduced in the spectra of N,N-dimethyl derivatives, indicating that the [(M + H - glycerol) - Hex](+) ion is formed from an intramolecular rearrangement with migration of the plasmal residue to the free amino group of sphingosine.	Nitrogen	49-50	hematopoietically expressed homeobox	Homo sapiens	115-118
14695889-6	2004	Animals treated with either HMGB1 antagonist were protected against the development of organ injury, as evidenced by improved levels of serum creatinine and blood urea nitrogen.	Nitrogen	168-176	high mobility group box 1	Mus musculus	28-33
24428582-4	2014	The electronic conductivity and protonation level on the nitrogen site of PPy films rapidly decreased with the increase of cyclic number.	Nitrogen	57-65	pancreatic polypeptide	Homo sapiens	74-77
12828642-5	2003	Arg82p and Kcs1p are required for activation of NCR-regulated genes in response to nitrogen availability, mainly through Nil1p, and for repression of PHO genes by phosphate.	Nitrogen	83-91	Gat1p	Saccharomyces cerevisiae S288C	121-126
14697754-8	2004	Three DNA N-glycosylases/AP lyases, Ntg1, Ntg2 and Ogg1, can also incise AP sites in DNA.	Nitrogen	7-8	bifunctional N-glycosylase/AP lyase NTG1	Saccharomyces cerevisiae S288C	36-40
24428582-9	2014	The continuous combination of detained EtMeIm(+) cations with doping anions of PTS(-) resulted in the rapid decrease of PPy protonation level on the nitrogen site and formation of compensate semiconductor state in PPy matrix.	Nitrogen	149-157	pancreatic polypeptide	Homo sapiens	120-123
24490900-0	2014	Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.	Nitrogen	0-8	mitogen-activated protein kinase 3	Mus musculus	116-122
14697754-8	2004	Three DNA N-glycosylases/AP lyases, Ntg1, Ntg2 and Ogg1, can also incise AP sites in DNA.	Nitrogen	7-8	bifunctional N-glycosylase/AP lyase NTG2	Saccharomyces cerevisiae S288C	42-46
15137438-1	2004	As a first step in treatment of high strength, strong nitrogenous landfill leachates (total COD--9.66-20.56 g/l, total nitrogen 780-1,080 mg/l), the performance of laboratory UASB reactors has been investigated under sub-mesophilic (19+/-3 degrees C) and psychrophilic (10+/-2 degrees C) conditions.	Nitrogen	54-62	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	92-95
12798431-9	2003	Administration of selective COX-2 inhibitor 24 h after HS, completely abrogated this delayed cardioprotection (46.4+/-3.6 and 48.0+/-2.8%, respectively, in HS+celecoxib and HS+NS-398 groups).	Nitrogen	176-178	prostaglandin-endoperoxide synthase 2	Rattus norvegicus	28-33
12796300-9	2003	Rapamycin treatment and nitrogen derepression may share some, but not all, regulatory elements, since Gln3p and Nil1p do not participate identically in both processes and are not required for hyperphosphorylation.	Nitrogen	24-32	Gat1p	Saccharomyces cerevisiae S288C	112-117
24519134-11	2014	We conclude that N- and CDH fetuses showed primary pulmonary hypoplasia, with a decrease in VEGFR1 and VEGFR2 expression.	Nitrogen	17-18	Fms related receptor tyrosine kinase 1	Rattus norvegicus	92-98
12820961-4	2003	In contrast, Tap42 inactivation, as does inactivation of the protein phosphatases Sit4 and Pph21/22, blocks rapamycin induction of nitrogen discrimination pathway genes.	Nitrogen	131-139	phosphoprotein phosphatase 2A catalytic subunit PPH21	Saccharomyces cerevisiae S288C	91-96
14671203-0	2003	Characterization of a circulating N-extended form of the thyrotropin-releasing hormone-like peptide pGlu-Glu-Pro amide in human plasma.	Nitrogen	34-35	thyrotropin releasing hormone	Homo sapiens	57-86
24396399-5	2014	Following the injection of MMP-9 into the renal arteries of the rabbits, significant improvements in renal morphology and serum levels of creatinine and urea nitrogen were observed.	Nitrogen	158-166	matrix metalloproteinase-9	Oryctolagus cuniculus	27-32
12970363-0	2003	N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.	Nitrogen	0-1	transient receptor potential cation channel subfamily C member 3	Homo sapiens	64-69
12970363-0	2003	N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.	Nitrogen	0-1	transient receptor potential cation channel subfamily C member 6	Homo sapiens	74-79
12970363-6	2003	Two NX(S/T) motifs in TRPC6 were mutated (Asn to Gln) by in vitro mutagenesis to delete one or both extracellular N-linked glycosylation sites.	Nitrogen	4-5	transient receptor potential cation channel subfamily C member 6	Homo sapiens	22-27
12624730-7	2003	Both the nitrogen and proton data indicate that the substrate analogue coenzyme M is axially coordinated to Ni(I) in the MCR(red2) state.	Nitrogen	9-17	adenosine deaminase RNA specific B2 (inactive)	Homo sapiens	125-129
24473128-5	2014	All 15 N-glycosylation sites of EBOV GP1 could be removed without compromising the expression of GP.	Nitrogen	7-8	GTP binding protein 1	Mus musculus	37-40
12691566-5	2003	Protonation with CF(3)SO(3)H acid occurs at the sp(2) nitrogen to give [PhN-(H) HC(C(3)F(7))-C(C(3)F(7))-NHPh][CF(3)SO(3)].	Nitrogen	54-62	carbamoyl-phosphate synthase 1	Homo sapiens	72-75
12691569-2	2003	Low temperature infrared spectra of light induced metastable states MS1 and MS2 of the nitroprusside anion in Na(2)[Fe(CN)(5)NO].2H(2)O, isotopically normal and substituted with (15)NO and N(18)O, are presented and discussed.	Nitrogen	110-111	MS	Homo sapiens	68-71
14698956-7	2003	RESULTS: In the present study, experiments in normal murine fibroblast C3H 10T1/2 cells demonstrated that the chemical inhibition of COX-2 activity with moderate doses of NS-398 abrogated IR-induced transformation events by fourfold and protected irradiated C3H 10T1/2 cells from clonogenic cell death.	Nitrogen	171-173	cytochrome c oxidase II, mitochondrial	Mus musculus	133-138
14530347-4	2003	All Ly-49s contain N-glycosylation motifs; however, the importance of receptor glycosylation in Ly-49-class I interactions has not been determined.	Nitrogen	19-20	killer cell lectin-like receptor, subfamily A, member 19	Mus musculus	4-10
12882965-2	2003	In repair of the N-alkylated purine base lesion, for example, alkyl adenine DNA glycosylase (Aag) recognizes and removes the base, and DNA polymerase beta (beta-pol) contributes the gap tailoring and DNA synthesis steps.	Nitrogen	17-18	DNA polymerase beta	Homo sapiens	135-154
12529169-0	2003	Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	153-157
12529169-0	2003	Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	158-162
12529169-0	2003	Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3.	Nitrogen	0-8	Gzf3p	Saccharomyces cerevisiae S288C	167-171
12529169-6	2003	We further show that Gzf3, another GATA zinc-finger protein, acts as a negative regulator in nitrogen-source control of CIS2 expression.	Nitrogen	93-101	Gzf3p	Saccharomyces cerevisiae S288C	21-25
12529169-9	2003	Furthermore, rapamycin causes similar CIS2 activation, indicating that the target of rapamycin signalling pathway controls CIS2 expression via Gln3 and Nil1 in nitrogen-starved cells.	Nitrogen	160-168	Gat1p	Saccharomyces cerevisiae S288C	152-156
12721102-17	2003	The highest intrinsic clearance (V(max)/K(m)) was found for CYP1A subfamily, CYP3A4 and CYP2B6 in the case of 5- sulphoxidation, and for CYP2C19, CYP1A subfamily and CYP2B6 in the case of N-demethylation.	Nitrogen	188-189	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	88-94
24900832-0	2014	Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning.	Nitrogen	67-75	zinc fingers and homeoboxes 2	Homo sapiens	45-48
14553833-5	2003	In addition, the treatment of HECs with N-LDL was also able to induce both E2F-1 gene transcription and protein expression.	Nitrogen	40-41	E2F transcription factor 1 L homeolog	Xenopus laevis	75-80
12683946-1	2003	Metabolism of the human chorionic gonadotrophin (hCG)- and LHbeta-subunits (hCGbeta, LHbeta) terminates with the urinary excretion of core fragment (hCGbetacf, LHbetacf) molecules that retain antigenic shape and constituent N-linked carbohydrate moieties.	Nitrogen	224-225	chorionic gonadotropin subunit beta 5	Homo sapiens	24-54
24900832-2	2014	The impact after nitrogen substitution on interactions between a derivative and its on- and off-target proteins (Raf/MEK, CYPs, and hERG channel) was also detected, most of them contributing to weaker interactions.	Nitrogen	17-25	zinc fingers and homeoboxes 2	Homo sapiens	113-116
14553833-8	2003	CONCLUSIONS: These results suggest that the activation of PKC/Raf/MEK/ERK-mediated events controlling E2F-1 gene expression by N-LDL may represent an important mechanism in the regulation of HECs proliferation during normal and pathological processes.	Nitrogen	2-3	mitogen-activated protein kinase 1 S homeolog	Xenopus laevis	70-73
14553833-8	2003	CONCLUSIONS: These results suggest that the activation of PKC/Raf/MEK/ERK-mediated events controlling E2F-1 gene expression by N-LDL may represent an important mechanism in the regulation of HECs proliferation during normal and pathological processes.	Nitrogen	2-3	E2F transcription factor 1 L homeolog	Xenopus laevis	102-107
24435307-4	2014	We provide evidence that TUSC3 is part of the OST complex and affects N-linked glycosylation in mammalian cells.	Nitrogen	70-71	tumor suppressor candidate 3	Homo sapiens	25-30
12756917-0	2003	Nitrogen fixation in transposon mutants from Bradyrhizobium japonicum USDA 110 impaired in nitrate reductase.	Nitrogen	0-8	inducible nitrate reductase [NADH] 1	Glycine max	91-108
24377322-0	2014	Rationally designed short polyisoprenol-linked PglB substrates for engineered polypeptide and protein N-glycosylation.	Nitrogen	102-103	epiphycan	Homo sapiens	47-51
12620851-3	2003	A pro3 ure2 strain expressing a PGK1 promoter-driven PUT2 allele encoding Delta(1)-pyrroline-5-carboxylate dehydrogenase lacking a mitochondrial targeting sequence produced significant cytoplasmic activity, accumulated twice as much intracellular glutamate, and produced twice as much cell mass as the parent when grown anaerobically on limiting arginine as sole nitrogen source.	Nitrogen	363-371	phosphoglycerate kinase	Saccharomyces cerevisiae S288C	32-36
12975333-11	2003	A mechanism for the p450-mediated ring scission is proposed in which the isoxazole ring nitrogen or oxygen coordinates to the reduced form of the heme followed by charge transfer from p450Fe(II) to the C=N bond or deprotonation of the C3-H, which results in a cleavage of the N-O bond.	Nitrogen	88-96	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	20-24
12734200-9	2003	Remarkably, the N-glycosylation profiles of CA125 and the envelope glycoprotein gp120 (derived from H9 lymphoblastoid cells chronically infected with HIV-1) are very similar.	Nitrogen	16-17	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	80-85
24377322-1	2014	The lipid carrier specificity of the protein N-glycosylation enzyme C. jejuni PglB was tested using a logical, synthetic array of natural and unnatural C10, C20, C30, and C40 polyisoprenol sugar pyrophosphates, including those bearing repeating cis-prenyl units.	Nitrogen	45-46	epiphycan	Homo sapiens	78-82
12943812-8	2003	Reduced viability following IR and nitrogen starvation was observed among strains deleted for CCR4 or DHH1 because of a defect in G1 to S phase checkpoint transition.	Nitrogen	35-43	CCR4-NOT core exoribonuclease subunit CCR4	Saccharomyces cerevisiae S288C	94-98
12943812-9	2003	Lethality following nitrogen starvation and IR was partially rescued in dhh1Delta strains by expressing the human ortholog of DHH1 (DDX6) which has been identified as a breakpoint oncogene.T CONCLUSIONS: hese results suggest that BRCA1 may promote genomic stability in human cells by interacting with the highly conserved ortholog of DHH1 (DDX6) to properly activate G1/S checkpoint arrest following DNA damage.	Nitrogen	20-28	DEAD-box helicase 6	Homo sapiens	132-136
12926555-8	2003	The observed changes indicate an impairment of N-deethylation, i.e. a possible decrease in enzymatic activity of CYP3A2 and CYP1A2, which are the major enzymes catalyzing this reaction.	Nitrogen	47-48	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	113-119
24328829-2	2014	Pyrolysis of Sn(Salen) at 650  C under Ar atmosphere was carried out to prepare N-doped porous 5-Sn/C with the BET specific surface area of 286.3 m(2) g(-1).	Nitrogen	80-81	delta/notch like EGF repeat containing	Homo sapiens	111-114
12590574-2	2003	The three-dimensional structure of (13)C-, (15)N-enriched human full-length apoCII in complex with sodium dodecyl sulfate (SDS) micelles is reported.	Nitrogen	47-48	apolipoprotein C2	Homo sapiens	76-82
12767213-3	2003	Samples of (15)N-labeled Ca(2+)-bound myristoylated recoverin bind anisotropically to phospholipid membranes as judged by analysis of (15)N and (31)P chemical shifts observed in solid-state NMR spectra.	Nitrogen	15-16	recoverin	Homo sapiens	52-61
24326190-12	2014	The negative effects of the PAH addition on the microbial nitrogen cycle were in six out of eight cases best correlated to the amount of alkylated bioavailable PAH in the sediments, and thus microbial nitrogen cycle is a possible good indicator for assessing PAH-induced stress.	Nitrogen	58-66	phenylalanine hydroxylase	Homo sapiens	28-31
12938735-6	2003	Mice with endowed defences against superoxide or with deficiency in the nNOS and iNOS are protected from MPTP toxicity suggesting that formation of reactive oxygen and nitrogen intermediates both intracellularly and extracellularly contributes to the demise of dopaminergic neurons.	Nitrogen	168-176	nitric oxide synthase 1, neuronal	Mus musculus	72-76
12918977-8	2003	This procedure applied to the bovine milk PP3 protein containing 25% modifications by weight yielded all known modifications (five phosphorylations, two O- and one N-glycosylation) as well as the previously unreported NeuNAc-Hex-[NeuNAc]HexNAc group O-linked to Ser60.	Nitrogen	164-165	glycosylation dependent cell adhesion molecule 1	Bos taurus	42-45
12429731-0	2003	Identification of the N-linked glycosylation sites on the high density lipoprotein (HDL) receptor SR-BI and assessment of their effects on HDL binding and selective lipid uptake.	Nitrogen	22-23	scavenger receptor class B, member 1	Mus musculus	98-103
12429731-1	2003	The murine class B, type I scavenger receptor mSR-BI, a high density lipoprotein (HDL) receptor that mediates selective uptake of HDL lipids, contains 11 potential N-linked glycosylation sites and unknown numbers of both endoglycosidase H-sensitive and -resistant oligosaccharides.	Nitrogen	164-165	scavenger receptor class B, member 1	Mus musculus	46-52
12429731-7	2003	Thus, N-linked glycosylation can influence both the intracellular transport and lipid-transporter activity of SR-BI.	Nitrogen	6-7	scavenger receptor class B, member 1	Mus musculus	110-115
12504349-6	2003	The uridine diphosphate-glucuronosyltransferase (UGT) enzyme(s) required for N- and O-glucuronidation have not been identified.	Nitrogen	77-78	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	4-47
24326190-12	2014	The negative effects of the PAH addition on the microbial nitrogen cycle were in six out of eight cases best correlated to the amount of alkylated bioavailable PAH in the sediments, and thus microbial nitrogen cycle is a possible good indicator for assessing PAH-induced stress.	Nitrogen	58-66	phenylalanine hydroxylase	Homo sapiens	160-163
12504349-6	2003	The uridine diphosphate-glucuronosyltransferase (UGT) enzyme(s) required for N- and O-glucuronidation have not been identified.	Nitrogen	77-78	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	49-52
12910288-6	2003	Our results suggest that (GCC)n-binding proteins differing from CGGBP-20 regulate activity of the VLDL receptor gene via cis-element (GCC)8.	Nitrogen	30-31	guanylate cyclase 2C	Homo sapiens	26-29
12910288-6	2003	Our results suggest that (GCC)n-binding proteins differing from CGGBP-20 regulate activity of the VLDL receptor gene via cis-element (GCC)8.	Nitrogen	30-31	guanylate cyclase 2C	Homo sapiens	134-137
24326190-12	2014	The negative effects of the PAH addition on the microbial nitrogen cycle were in six out of eight cases best correlated to the amount of alkylated bioavailable PAH in the sediments, and thus microbial nitrogen cycle is a possible good indicator for assessing PAH-induced stress.	Nitrogen	58-66	phenylalanine hydroxylase	Homo sapiens	160-163
24326190-12	2014	The negative effects of the PAH addition on the microbial nitrogen cycle were in six out of eight cases best correlated to the amount of alkylated bioavailable PAH in the sediments, and thus microbial nitrogen cycle is a possible good indicator for assessing PAH-induced stress.	Nitrogen	201-209	phenylalanine hydroxylase	Homo sapiens	28-31
26138778-4	2014	In this study we developed two cell lines resistant to the alkylating agents nitrogen mustard (HN2) and cisplatin (Pt).	Nitrogen	77-85	MT-RNR2 like 2 (pseudogene)	Homo sapiens	95-98
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	115-116	adrenoceptor beta 1	Homo sapiens	9-18
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	115-116	adrenoceptor beta 1	Homo sapiens	89-98
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	115-116	adrenoceptor beta 1	Homo sapiens	89-98
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	133-134	adrenoceptor beta 1	Homo sapiens	9-18
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	133-134	adrenoceptor beta 1	Homo sapiens	89-98
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	133-134	adrenoceptor beta 1	Homo sapiens	89-98
12489124-1	2003	The role of Gln3p, Nil1p, Dal80p and Ure2p in the nitrogen regulation of ASP3, which codes for the periplasmic Saccharomyces cerevisiae asparaginase II, was investigated.	Nitrogen	50-58	Gat1p	Saccharomyces cerevisiae S288C	19-24
12489124-1	2003	The role of Gln3p, Nil1p, Dal80p and Ure2p in the nitrogen regulation of ASP3, which codes for the periplasmic Saccharomyces cerevisiae asparaginase II, was investigated.	Nitrogen	50-58	asparaginase ASP3-1	Saccharomyces cerevisiae S288C	73-77
12489124-4	2003	Enzyme activity doubled upon nitrogen starvation of either ammonium-grown (possibly due to Nil2p/Deh1p derepression) or proline-grown (due to Dal80p derepression) cells.	Nitrogen	29-37	Gzf3p	Saccharomyces cerevisiae S288C	91-96
12489124-4	2003	Enzyme activity doubled upon nitrogen starvation of either ammonium-grown (possibly due to Nil2p/Deh1p derepression) or proline-grown (due to Dal80p derepression) cells.	Nitrogen	29-37	Gzf3p	Saccharomyces cerevisiae S288C	97-102
12520306-8	2003	This indicates that Srb10 controls Ste12 activity for filamentous growth in response to nitrogen limitation and is consistent with the hypothesis that Srb10 regulates gene-specific activators in response to physiological signals to coordinate gene expression with growth potential.	Nitrogen	88-96	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	35-40
24323398-3	2014	After 48 h of culture under nitrogen with a resulting medium pH of 7.8, sorted hypoxic PC3 cells yielded a higher percentage and concentration/10(5) of cells in a doubly labeled (DL) CD44(+)/CD41(+) side fraction compared with control cells cultured under normoxia (5 % CO2 in the ambient atmosphere at 37  C).	Nitrogen	28-36	chromobox 8	Mus musculus	87-90
12519192-5	2003	We also identified the intracellular nitrogen pool(s) responsible for the modulation of expression of AMT1, AMT2, AMT3, GDHA and GLNA.	Nitrogen	37-45	ammonium permease MEP1	Saccharomyces cerevisiae S288C	102-106
12519192-6	2003	In response to exogenously supplied ammonium or glutamine, AMT1, AMT2 and GDHA were downregulated and, therefore, these genes are subjected to nitrogen repression in H. cylindrosporum.	Nitrogen	143-151	ammonium permease MEP1	Saccharomyces cerevisiae S288C	59-63
12722443-8	2003	N uptake under NPM and NP treatments was significantly decreased in dry year.	Nitrogen	0-1	nucleophosmin 1	Homo sapiens	15-18
12433823-10	2002	In conclusion, the involvement of UGT1A1 and UGT1A9 as well as UGT1A4 in nicotine and cotinine N-glucuronidations in human liver microsomes was suggested, although the contributions of each UGT isoform could not be determined conclusively.	Nitrogen	95-96	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	34-37
12356334-0	2003	Differences in N-linked glycosylation between human surfactant protein-B variants of the C or T allele at the single-nucleotide polymorphism at position 1580: implications for disease.	Nitrogen	15-16	surfactant protein B	Homo sapiens	52-72
12356334-5	2003	The Thr131--&gt;Ile substitution can eliminate a potential N-linked glycosylation site, Asn129-Gln-Thr131, which is present in the SP-B variant of the C allele (ACT/Thr) but not in that of the T allele (ATT/Ile).	Nitrogen	59-60	surfactant protein B	Homo sapiens	131-135
12356334-8	2003	In addition, we also confirmed that both SP-B variants contain another N-linked glycosylation site, Asn311-Ser-Ser313.	Nitrogen	71-72	surfactant protein B	Homo sapiens	41-45
12356334-10	2003	Further, we speculate that, given the fact that this SNP is found frequently in the general population, N-linked glycosylation at residue Asn129 interferes with SP-B processing, secretion and folding under certain disease conditions.	Nitrogen	54-55	surfactant protein B	Homo sapiens	161-165
14682566-3	2003	However, based on this SCOD removal in the nitrification step, a consequent post-denitrification process without nitrate recycle and dosage of external carbon sources has been proven to reach substantial nitrate elimination of up to 20 mg nitrogen per litre at COD/N-ratios of approx.	Nitrogen	239-247	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	24-27
14682566-5	2003	At such COD/N-ratios, suitable nitrogen elimination seems to be possible, because the bioflocs of settled sewage, produced so far by SCOD oxidation and entrapment of particulate COD, are passing through the nitrification process having a substantial contribution to the denitrification rate additionally to the remaining SCOD.	Nitrogen	31-39	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	8-11
14682566-5	2003	At such COD/N-ratios, suitable nitrogen elimination seems to be possible, because the bioflocs of settled sewage, produced so far by SCOD oxidation and entrapment of particulate COD, are passing through the nitrification process having a substantial contribution to the denitrification rate additionally to the remaining SCOD.	Nitrogen	31-39	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	134-137
24415948-3	2014	We find that rapid adaptive evolution in nitrogen-poor environments is dominated by the de novo generation and selection of copy number variants (CNVs), a large fraction of which contain genes encoding specific nitrogen transporters including PUT4, DUR3 and DAL4.	Nitrogen	41-49	proline permease PUT4	Saccharomyces cerevisiae S288C	243-247
12417426-5	2002	Integrin receptor clustering and cell motility are also sensitive to changes in Mgat5-dependent N-glycosylation.	Nitrogen	96-97	mannoside acetylglucosaminyltransferase 5	Mus musculus	80-85
12523505-6	2002	Experimental results showed that steam was sightly more effective than nitrogen at regenerating the total micropore volume and BET surface area of the carbons.	Nitrogen	71-79	delta/notch like EGF repeat containing	Homo sapiens	127-130
12487819-3	2002	gp120 is extensively glycosylated, with N-linked complex and high mannose carbohydrates accounting for about half of the molecular weight.	Nitrogen	40-41	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	0-5
12447538-4	2002	This observation suggests that, in conjunction with GS, GDH plays a major role in controlling the translocation of organic carbon and nitrogen metabolites in both vegetative and reproductive organs.	Nitrogen	134-142	L-galactose dehydrogenase	Vitis vinifera	56-59
25509891-15	2014	CONCLUSION: Epoetin beta used in patients with CGN has an anti-anemic effect and leads to improved renal nitrogen-excretory function.	Nitrogen	105-113	cingulin	Homo sapiens	47-50
12447538-6	2002	Although the function of such organelles is still unknown, its is possible that the presence of GDH in such cellular structures is important for the recycling of carbon and nitrogen molecules in senescing tissues in which the enzyme is generally induced.	Nitrogen	173-181	L-galactose dehydrogenase	Vitis vinifera	96-99
12427993-3	2002	Ammonium influx into roots and AtAMT1;1 mRNA expression levels are highly correlated diurnally and when plant nitrogen (N) status is varied.	Nitrogen	110-118	ammonium transporter 1;1	Arabidopsis thaliana	31-39
12138100-11	2002	These combined results indicate that the synergistic effect of ST8Sia II and ST8Sia IV is caused by: 1) the ability of ST8Sia IV to add polysialic acid to oligosialic acid formed by ST8Sia II, 2) the potential of ST8Sia IV to act on more antennas of N-glycans than ST8Sia II, and 3) the ability of ST8Sia II and ST8Sia IV in combination to act on the fifth and sixth N-glycosylation sites of NCAM.	Nitrogen	250-251	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	77-86
12138100-11	2002	These combined results indicate that the synergistic effect of ST8Sia II and ST8Sia IV is caused by: 1) the ability of ST8Sia IV to add polysialic acid to oligosialic acid formed by ST8Sia II, 2) the potential of ST8Sia IV to act on more antennas of N-glycans than ST8Sia II, and 3) the ability of ST8Sia II and ST8Sia IV in combination to act on the fifth and sixth N-glycosylation sites of NCAM.	Nitrogen	250-251	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	119-128
12198133-13	2002	The specificity, subcellular location, and topological orientation of the active site described in the current study strongly support a role for Dolpp1p in the recycling of Dol-P-P discharged during protein N-glycosylation reactions on the luminal leaflet of the endoplasmic reticulum in mammalian cells.	Nitrogen	207-208	dolichyldiphosphatase 1	Homo sapiens	145-152
24092384-6	2013	I/R markedly depressed renal blood flow and increased the production in O2, PGE2, the expression in P47 and Rac-1 expression of two nicotinamide adenine dinucleotide phosphate oxidase subunits, cytosolic cytochrome C release, proapoptotic marker lamin expression, the pathologic appearance of necrosis, apoptosis, and autophagy, and blood urea nitrogen and creatinine levels in the damaged kidneys.	Nitrogen	344-352	Rac family small GTPase 1	Rattus norvegicus	108-113
12244056-7	2002	Thus AAP8 is probably responsible for import of organic nitrogen into developing seeds.	Nitrogen	56-64	amino acid permease 8	Arabidopsis thaliana	5-9
12199704-7	2002	Three N-glycopeptides of ZPA, containing an N-glycosylation site at Asn83, Asn191 and Asn527, respectively, were obtained from endo-beta-Galactosidase-digested ZPA.	Nitrogen	6-7	zona pellucida glycoprotein 2	Homo sapiens	25-28
12199704-7	2002	Three N-glycopeptides of ZPA, containing an N-glycosylation site at Asn83, Asn191 and Asn527, respectively, were obtained from endo-beta-Galactosidase-digested ZPA.	Nitrogen	44-45	zona pellucida glycoprotein 2	Homo sapiens	25-28
24304387-7	2013	Quite interestingly, methylation of the central amide nitrogen strongly altered the high affinity for ABCG2 and the complete inhibition of mitoxantrone efflux and coupled ATPase activity.	Nitrogen	54-62	dynein axonemal heavy chain 8	Homo sapiens	171-177
12428686-3	2002	The increase in blood urea nitrogen in the DBA/B6 strain of PGHS-2 null mice was significantly lower than reported for B6 PGHS-2 null mice (200% versus 270%).	Nitrogen	27-35	prostaglandin-endoperoxide synthase 2	Mus musculus	60-66
12167012-2	2002	1 reacts reversibly with dinitrogen to afford dimeric [[U(eta-Cp)(eta-C(8)H(4)[Si(i)Pr(3)-1,4](2))](2)(mu-eta(2):eta(2)-N(2))] 2, whose X-ray crystal structure reveals a sideways-bound, bridging diazenido (N(2)(2-)) ligand.	Nitrogen	25-35	endothelin receptor type A	Homo sapiens	58-61
12167012-2	2002	1 reacts reversibly with dinitrogen to afford dimeric [[U(eta-Cp)(eta-C(8)H(4)[Si(i)Pr(3)-1,4](2))](2)(mu-eta(2):eta(2)-N(2))] 2, whose X-ray crystal structure reveals a sideways-bound, bridging diazenido (N(2)(2-)) ligand.	Nitrogen	25-35	endothelin receptor type A	Homo sapiens	66-69
12167012-2	2002	1 reacts reversibly with dinitrogen to afford dimeric [[U(eta-Cp)(eta-C(8)H(4)[Si(i)Pr(3)-1,4](2))](2)(mu-eta(2):eta(2)-N(2))] 2, whose X-ray crystal structure reveals a sideways-bound, bridging diazenido (N(2)(2-)) ligand.	Nitrogen	25-35	endothelin receptor type A	Homo sapiens	66-69
12175333-7	2002	Moreover, transfecting CST mutants lacking both N-glycosylation sites, or only Asn-312, reduced significantly the amount of sulphatide synthesized, whereas substituting Asn-66 with a glutamine residue did not.	Nitrogen	48-49	galactose-3-O-sulfotransferase 1	Mus musculus	23-26
12175333-11	2002	Expression of fully active CST in a CHO-glycosylation mutant lacking N-acetylglucosaminyltransferase I demonstrated that condensation of the N-linked pentamannosyl-core structure is sufficient to form a fully active enzyme.	Nitrogen	69-70	galactose-3-O-sulfotransferase 1	Mus musculus	27-30
12484518-5	2002	Increased plasma renin activity (23 +/- 8 ng/kg/h (n = 6) vs. sham operation, 2.4 +/- 0.9 ng/kg/h (n = 4)) was markedly reduced to 6.8 +/- 2.7 ng/ml/h (n = 5) by NS-398, but not by mofezolac.	Nitrogen	162-164	renin	Rattus norvegicus	17-22
12167012-2	2002	1 reacts reversibly with dinitrogen to afford dimeric [[U(eta-Cp)(eta-C(8)H(4)[Si(i)Pr(3)-1,4](2))](2)(mu-eta(2):eta(2)-N(2))] 2, whose X-ray crystal structure reveals a sideways-bound, bridging diazenido (N(2)(2-)) ligand.	Nitrogen	25-35	endothelin receptor type A	Homo sapiens	66-69
24164404-5	2013	Here, we show the feasibility of formerly N-glycopeptide identification and quantification at MS1 level using genomic N-glycosite prediction (GenoGlyco) coupled with stable isotopic labeling and accurate mass matching.	Nitrogen	42-43	MS	Homo sapiens	94-97
12196392-6	2002	In addition, Ypk1 as well as eIF4G protein levels were rapidly depleted upon nitrogen starvation, but not during glucose starvation, even though both conditions inhibit translation initiation.	Nitrogen	77-85	serine/threonine protein kinase YPK1	Saccharomyces cerevisiae S288C	13-17
12421340-9	2002	The N-POMC isoforms appeared to be N- and at least in part O-glycosylated.	Nitrogen	4-5	pro-opiomelanocortin-alpha	Mus musculus	6-10
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	16-17	pro-opiomelanocortin-alpha	Mus musculus	48-52
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	16-17	pro-opiomelanocortin-alpha	Mus musculus	144-149
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	16-17	pro-opiomelanocortin-alpha	Mus musculus	200-205
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	46-47	pro-opiomelanocortin-alpha	Mus musculus	48-52
24002332-0	2013	Allele-specific N-glycosylation delays human surfactant protein B secretion in vitro and associates with decreased protein levels in vivo.	Nitrogen	16-17	surfactant protein B	Homo sapiens	45-65
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	46-47	pro-opiomelanocortin-alpha	Mus musculus	144-149
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	46-47	pro-opiomelanocortin-alpha	Mus musculus	200-205
12487729-5	2002	The objective was to use cDNA-expressed individual rat CYP enzyme preparations in microsomes prepared from baculovirus-infected insect cells to determine which rat CYP enzymes were the source of N-alkylPPs after interaction with three porphyrinogenic xenobiotics and to compare the results with formation of N-alkylPPs in individual human CYP enzyme orthologues.	Nitrogen	27-28	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	55-58
12079284-7	2002	Western blot analysis revealed that CHODL is an N-glycosylated protein with a molecular weight of approximately 36 kDa.	Nitrogen	48-49	chondrolectin	Homo sapiens	36-41
12115478-1	2002	Muc4 (also called sialomucin complex), the rat homolog of human MUC4, is a heterodimeric glycoprotein complex that consists of a peripheral O-glycosylated mucin subunit, ASGP-1, tightly but noncovalently linked to a N-glycosylated transmembrane subunit, ASGP-2.	Nitrogen	216-217	mucin 4, cell surface associated	Homo sapiens	64-68
12398616-0	2002	Giant magnetic moments of nitrogen-doped Mn clusters and their relevance to ferromagnetism in Mn-doped GaN.	Nitrogen	26-34	gigaxonin	Homo sapiens	103-106
24002332-3	2013	SFTPB single-nucleotide polymorphism Ile131Thr affects proSP-B N-glycosylation in humans and the glycosylated Thr variant associates with pulmonary diseases.	Nitrogen	63-64	surfactant protein B	Homo sapiens	0-5
24002332-7	2013	Our results suggest that Ile131Thr variation-dependent N-glycosylation associates with decreased levels of SP-B, which is secreted from fetal lung to amniotic fluid.	Nitrogen	55-56	surfactant protein B	Homo sapiens	107-111
24171660-8	2013	For PAH/citrate, by increasing the PAH/citrate spraying rate ratio, the carboxylic/nitrogen ratio in the film increases and tends to 1.	Nitrogen	83-91	phenylalanine hydroxylase	Homo sapiens	4-7
12356739-1	2002	Rcd1, initially identified as a factor essential for the commitment to nitrogen starvation-invoked differentiation in fission yeast, is one of the most conserved proteins found across eukaryotes, and its mammalian homolog is expressed in a variety of differentiating tissues.	Nitrogen	71-79	CCR4-NOT transcription complex, subunit 9	Mus musculus	0-4
12366798-0	2002	An engineered phosphoenolpyruvate carboxylase redirects carbon and nitrogen flow in transgenic potato plants.	Nitrogen	67-75	phosphoenolpyruvate carboxylase	Solanum tuberosum	14-45
12479218-2	2002	In the present study, we have assessed the cytotoxic activity in vitro of (N)-MCT in wild-type murine colon cancer cells (MC38) and in cells expressing the herpes simplex thymidine kinase gene (MC38/HSV-tk), and the antitumor activity of (N)-MCT in vivo against HSV-tk transduced and nontransduced MC38 murine tumors.	Nitrogen	75-77	microcephaly, primary autosomal recessive 1	Mus musculus	78-81
12479218-2	2002	In the present study, we have assessed the cytotoxic activity in vitro of (N)-MCT in wild-type murine colon cancer cells (MC38) and in cells expressing the herpes simplex thymidine kinase gene (MC38/HSV-tk), and the antitumor activity of (N)-MCT in vivo against HSV-tk transduced and nontransduced MC38 murine tumors.	Nitrogen	75-77	microcephaly, primary autosomal recessive 1	Mus musculus	242-245
12046086-1	2002	AIM: Critical illnesses such as sepsis, trauma, and burns cause a growth hormone insensitivity, which leads to an increased negative nitrogen balance.	Nitrogen	133-141	gonadotropin releasing hormone receptor	Rattus norvegicus	66-80
12015208-3	2002	This paper reports the presence of N-glycosylated phosducin-like protein long (PhLP(L)) in all structures of mouse CNS, mainly in synaptic plasma membranes and associated with G beta subunits and 14-3-3 proteins.	Nitrogen	35-36	phosducin-like	Mus musculus	79-83
12138100-11	2002	These combined results indicate that the synergistic effect of ST8Sia II and ST8Sia IV is caused by: 1) the ability of ST8Sia IV to add polysialic acid to oligosialic acid formed by ST8Sia II, 2) the potential of ST8Sia IV to act on more antennas of N-glycans than ST8Sia II, and 3) the ability of ST8Sia II and ST8Sia IV in combination to act on the fifth and sixth N-glycosylation sites of NCAM.	Nitrogen	250-251	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	119-128
12138100-11	2002	These combined results indicate that the synergistic effect of ST8Sia II and ST8Sia IV is caused by: 1) the ability of ST8Sia IV to add polysialic acid to oligosialic acid formed by ST8Sia II, 2) the potential of ST8Sia IV to act on more antennas of N-glycans than ST8Sia II, and 3) the ability of ST8Sia II and ST8Sia IV in combination to act on the fifth and sixth N-glycosylation sites of NCAM.	Nitrogen	250-251	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	119-128
24171660-8	2013	For PAH/citrate, by increasing the PAH/citrate spraying rate ratio, the carboxylic/nitrogen ratio in the film increases and tends to 1.	Nitrogen	83-91	phenylalanine hydroxylase	Homo sapiens	35-38
12270132-2	2002	We show here that the beta(1)AR is glycosylated in various cell types and that mutation of the single predicted site of N-linked glycosylation (N15A) results in the formation of receptors that are not N-glycosylated.	Nitrogen	120-121	adrenoceptor beta 1	Homo sapiens	22-31
24241090-6	2013	Visfatin showed significant positive correlations with low-density lipoprotein cholesterol, uric acid, blood urea nitrogen, creatinine, brain natriuretic peptide, E-selectin, total leukocyte count, neutrophil count, and high-sensitivity C-reactive protein, and a significant negative correlation with estimated glomerular filtration rate and albumin.	Nitrogen	114-122	nicotinamide phosphoribosyltransferase	Homo sapiens	0-8
12351147-1	2002	N-oxidation by cytochrome p450 enzymes is an initial step in the metabolic activation of aromatic amine compounds.	Nitrogen	0-1	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	26-30
12236755-5	2002	Under standard thermodynamic conditions (STP), C-H addition via the D pathway has DeltaG(o)(+ +) = 36.3 kcal/mol for CyH (35.1 kcal/mol for n-PrH).	Nitrogen	1-2	sulfotransferase family 1A member 1	Homo sapiens	41-44
12236755-5	2002	Under standard thermodynamic conditions (STP), C-H addition via the D pathway has DeltaG(o)(+ +) = 36.3 kcal/mol for CyH (35.1 kcal/mol for n-PrH).	Nitrogen	1-2	hematopoietically expressed homeobox	Homo sapiens	142-145
12030331-5	2002	DIBD1 is predicted to encode a mannosyltransferase similar to Saccaromyces cerevisiae Alg9p of the protein N-glycosylation pathway.	Nitrogen	107-108	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	0-5
12030331-5	2002	DIBD1 is predicted to encode a mannosyltransferase similar to Saccaromyces cerevisiae Alg9p of the protein N-glycosylation pathway.	Nitrogen	107-108	dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase	Saccharomyces cerevisiae S288C	86-91
12236755-7	2002	At conditions under which acceptorless dehydrogenation is thermodynamically possible (for example, T = 150 degrees C and P(H)2 = 1.0 x 10(-7) atm), DeltaG(+ +) for C-H addition to ((Me)PCP)Ir (plus a molecule of free H(2)) is very low (17.5 kcal/mol for CyH, 16.7 kcal/mol for n-PrH).	Nitrogen	5-6	hematopoietically expressed homeobox	Homo sapiens	279-282
23971515-5	2013	Among the identified proteins of H. seropedicae, the dinitrogenase reductase NifH and glutamine synthetase GlnA, which participate in nitrogen fixation and ammonium assimilation, respectively, were the most abundant.	Nitrogen	55-63	type I glutamate--ammonia ligase	Herbaspirillum seropedicae	107-111
12236755-9	2002	For CyH, the calculated DeltaG(o)(+ +) for C-H addition to ((Me)PCP)IrH(2) on the A pathway is 35.2 kcal/mol (32.7 kcal/mol for n-PrH).	Nitrogen	54-55	hematopoietically expressed homeobox	Homo sapiens	130-133
12165425-2	2002	Under nitrogen-rich conditions, the GATA family transcriptional activators, Gln3 and Gat1, form complexes with Ure2, and are localized to the cytoplasm, which decreases NCR-sensitive expression.	Nitrogen	6-14	Gat1p	Saccharomyces cerevisiae S288C	85-89
12165425-3	2002	Under nitrogen-limiting conditions, Gln3 and Gat1 are dephosphorylated, move from the cytoplasm to the nucleus, in wild-type but not rna1 and srp1 mutants, and increase expression of NCR-sensitive genes.	Nitrogen	6-14	Gat1p	Saccharomyces cerevisiae S288C	45-49
11904149-1	2002	The yeast high-affinity glucose transporters Hxt6p and Hxt7p are rapidly degraded during nitrogen starvation in the presence of high concentrations of fermentable carbon sources.	Nitrogen	89-97	hexose transporter HXT7	Saccharomyces cerevisiae S288C	55-60
11750083-9	2002	Serum alanine aminotransferase activity and blood urea nitrogen levels, indicative of hepatic and renal damage respectively, were increased 4 to 6-fold in the mdr1a/1b(-/-) mice as compared with 1-2-fold increases in wild-type mice.	Nitrogen	55-63	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	Mus musculus	159-164
23970553-7	2013	However, this effect was independent of the N-glycosylation state of TRPV5, since the N-glycosylation mutant (TRPV5(N358Q)) was activated to the same extent.	Nitrogen	86-87	transient receptor potential cation channel subfamily V member 5	Homo sapiens	110-115
12147719-2	2002	(1) Nitrate reductase catalyses the key step in inorganic nitrogen assimilation, (2) aldehyde oxidase(s) have been shown to catalyse the last step in the biosynthesis of the phytohormone abscisic acid, (3) xanthine dehydrogenase is involved in purine catabolism and stress reactions, and (4) sulphite oxidase is probably involved in detoxifying excess sulphite.	Nitrogen	58-66	xanthine dehydrogenase	Homo sapiens	206-228
12130708-4	2002	Furthermore, depletion of PKC by 12-O-tetradecanoylphorbol-13-acetate exposure (48 h, 1 microM) also prevented OFQ/N-mediated mu and ORL1 desensitization.	Nitrogen	115-116	opioid related nociceptin receptor 1	Homo sapiens	133-137
11777465-3	2002	These results suggested that the formation of lithium aggregates at the neighboring of the pyridinic nitrogen atom favored BuLi delivery at C-6 as well as 6-lithio intermediate stabilization.	Nitrogen	101-109	complement C6	Homo sapiens	140-143
25474892-2	2013	This determinant causes the nonsense suppression in strains that bear different N-substituted variants of Sup35p, which is a translation release factor eRF3.	Nitrogen	80-81	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	106-112
12640179-1	2002	We tested the response of stress-activated mitogen-activated protein kinases (MAPKs) - p38 MAPK and c-JUN NH2-terminal kinase (JNK) - following hypoxia-ischemia (H-I) induced by unilateral carotid artery ligation and hypoxia (8% O2 and 92% N2) for 2.5 h in postnatal-day-7 rats.	Nitrogen	240-242	mitogen activated protein kinase 14	Rattus norvegicus	87-90
11994306-7	2002	Here we have investigated the relationship between the two N-linked glycosylation sites (Asn(10) and Asn(1050)) and SUR1 trafficking.	Nitrogen	59-60	ATP binding cassette subfamily C member 8	Homo sapiens	116-120
23935103-11	2013	These data indicate that the five commonly used nitrogen-related conditions of down-regulating TorC1 are not physiologically equivalent and minimally involve partially differing regulatory mechanisms.	Nitrogen	48-56	CREB regulated transcription coactivator 1	Homo sapiens	95-100
12114572-7	2002	Under nitrogen or carbon-starvation conditions, chlorosis was observed earlier in atapg9-1 cotyledons and rosette leaves compared with wild-type plants.	Nitrogen	6-14	autophagy 9 (APG9)	Arabidopsis thaliana	82-88
12114572-8	2002	Furthermore, atapg9-1 exhibited a reduction in seed set when nitrogen starved.	Nitrogen	61-69	autophagy 9 (APG9)	Arabidopsis thaliana	13-19
11956206-6	2002	hCERK also has a putative N-myristoylation site on its NH(2) terminus followed by a pleckstrin homology domain.	Nitrogen	26-27	ceramide kinase	Homo sapiens	0-5
15618670-4	2002	CYP2B6 had a higher affinity for both N-depropagylation (K(m)=21.4 microM) and N-demethylation (K(m)=25.2 microM) of selegiline than CYP3A4 and CYP1A2.	Nitrogen	38-39	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-6
11697887-9	2001	Although within this region of human CTGF is a N-glycosylation site, tunicamycin, which blocks N-linked glycosylation, has no significant effect on CTGF secretion.	Nitrogen	47-48	cellular communication network factor 2	Homo sapiens	37-41
23959767-1	2013	Direct evidence of the conformation of a Pd-N heterocyclic carbene (NHC) moiety imbedded in a hybrid material and of the Pd-NHC bond were obtained by dynamic nuclear polarization surface-enhanced NMR spectroscopy (DNP SENS) at natural abundance in short experimental times (hours).	Nitrogen	44-45	potassium channel tetramerization domain containing 1	Homo sapiens	218-222
11839462-3	2001	Significantly, we found that chronic ethanol consumption markedly inhibits hepatic sialylation of apolipoprotein J (Apo J), a 70-kDa N-glycosylated protein of plasma HDL.	Nitrogen	133-134	clusterin	Homo sapiens	98-114
11839462-3	2001	Significantly, we found that chronic ethanol consumption markedly inhibits hepatic sialylation of apolipoprotein J (Apo J), a 70-kDa N-glycosylated protein of plasma HDL.	Nitrogen	133-134	clusterin	Homo sapiens	116-121
12044882-0	2002	Complex N-glycosylated form of nicastrin is stabilized and selectively bound to presenilin fragments.	Nitrogen	8-9	nicastrin	Homo sapiens	31-40
23761407-5	2013	Consistent with its nuclear localization, N2 inhibits IRF3 downstream of the TANK-binding kinase (TBK)-1 and after IRF3 translocation into the nucleus.	Nitrogen	42-44	interferon regulatory factor 3	Homo sapiens	54-58
12044882-3	2002	Here we show that Endo H-resistant, N-glycosylated form of nicastrin (p150-NCT) is highly stabilized and selectively bound to PS fragments.	Nitrogen	36-37	nicastrin	Homo sapiens	59-68
12044882-3	2002	Here we show that Endo H-resistant, N-glycosylated form of nicastrin (p150-NCT) is highly stabilized and selectively bound to PS fragments.	Nitrogen	36-37	chromatin assembly factor 1 subunit A	Homo sapiens	70-74
11986784-3	2002	Nitrogen-containing bisphosphonates including zoledronic acid have been shown to induce apoptosis associated with PARP cleavage and DNA fragmentation.	Nitrogen	0-8	collagen type XI alpha 2 chain	Homo sapiens	114-118
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	139-147	melanocortin 3 receptor	Homo sapiens	255-258
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	139-147	melanocortin 3 receptor	Homo sapiens	315-318
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	245-253	melanocortin 3 receptor	Homo sapiens	255-258
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	245-253	melanocortin 3 receptor	Homo sapiens	315-318
23761407-5	2013	Consistent with its nuclear localization, N2 inhibits IRF3 downstream of the TANK-binding kinase (TBK)-1 and after IRF3 translocation into the nucleus.	Nitrogen	42-44	interferon regulatory factor 3	Homo sapiens	115-119
11606127-9	2001	However, as CYP 2C8 and 2C18, CYP 2C19 showed a much better affinity for neutral compounds derived from N-alkylation of SPA and for anionic compounds bearing a larger R(1) substituent.	Nitrogen	104-105	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	12-19
23848058-4	2013	The nitrogen adsorption-desorption was used for determination of surface area (BET) and porosity.	Nitrogen	4-12	delta/notch like EGF repeat containing	Homo sapiens	79-82
11679080-8	2001	Additionally, the proper transcription of several nitrogen-regulated genes, including NIL1 and DAL80, encoding well-studied GATA transcription factors, is dependent upon Ssy1p.	Nitrogen	50-58	Gat1p	Saccharomyces cerevisiae S288C	86-90
11942843-3	2002	The method, which combines features of single- and double-quantum NMR spectroscopy, allows one to cancel the effects of dominant short-range dipolar interactions (e.g., between the CSA of the amide nitrogen N and the dipolar coupling to its attached proton H(N)) and is designed so that the secular approximation is rescued even if the scalar coupling between the long-range dipolar coupling partners is very small.	Nitrogen	198-206	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	181-184
23931318-5	2013	In a next step a set of four solid-state NMR angular restraints was obtained from huntingtin 1-17 labeled with (15)N and (2)H at selected sites.	Nitrogen	41-42	huntingtin	Homo sapiens	82-92
11909625-1	2002	Putrescine:SAM N-methyltransferase (PMT) catalyses the N-methylation of the diamine putrescine to form N-methylputrescine, the first specific precursor of both tropane and pyridine-type alkaloids, which are present together in the roots of Duboisia plants.	Nitrogen	15-16	putrescine N-methyltransferase 3	Nicotiana tabacum	36-39
11971139-9	2002	In plants, AtUPS1 gene expression was dependent on the nitrogen source.	Nitrogen	55-63	ureide permease 1	Arabidopsis thaliana	11-17
11511107-7	2001	This study provides important information regarding the specificity of the used antibody, indicates that ClC-3 is widely expressed in mouse, and that mClC-3 undergoes differential tissue-specific N-glycosylation.	Nitrogen	196-197	Charcot-Leyden crystal protein	Mus musculus	150-154
23883100-6	2013	The cationic clusters [{Pd3}(CO)2(L)]PF6 (L = NCCH3, Py or CO) were obtained by reacting {Pd3}(CO)2I with TlPF6, under nitrogen in acetonitrile or in pyridine or under 1 atm of carbon monoxide in THF.	Nitrogen	119-127	sperm associated antigen 17	Homo sapiens	37-40
11356843-8	2001	Patterns of gene expression in a vid30 Delta suggest that the Vid30p function shifts the balance of nitrogen metabolism toward the production of glutamate, especially when cells are grown in low ammonia.	Nitrogen	100-108	glucose-induced degradation complex subunit VID30	Saccharomyces cerevisiae S288C	33-38
11356843-8	2001	Patterns of gene expression in a vid30 Delta suggest that the Vid30p function shifts the balance of nitrogen metabolism toward the production of glutamate, especially when cells are grown in low ammonia.	Nitrogen	100-108	glucose-induced degradation complex subunit VID30	Saccharomyces cerevisiae S288C	62-68
11356843-9	2001	CAN1, DAL4, DAL5, MEP2, DAL1, DAL80, and GDH3 transcription is down-regulated by Vid30p function with proline as the nitrogen source.	Nitrogen	117-125	glucose-induced degradation complex subunit VID30	Saccharomyces cerevisiae S288C	81-87
12702356-7	2001	A few genes, FSP2, RGS2, AQY1, YFL030W, were expressed more strongly with nitrogen limitation as compared to other conditions.	Nitrogen	74-82	oligo-1,6-glucosidase IMA4	Saccharomyces cerevisiae S288C	13-17
11414817-9	2001	X-band spectra of these cryoreduced samples, and of conventionally prepared MCR(red1) and MCR(ox1), all show resolved hyperfine splitting from four equivalent nitrogen ligands with coupling constants in agreement with those determined in previous EPR studies and from (14)N ENDOR of MCR(red1) and MCR(ox1).	Nitrogen	159-167	nuclear receptor subfamily 3 group C member 2	Homo sapiens	76-79
11414817-9	2001	X-band spectra of these cryoreduced samples, and of conventionally prepared MCR(red1) and MCR(ox1), all show resolved hyperfine splitting from four equivalent nitrogen ligands with coupling constants in agreement with those determined in previous EPR studies and from (14)N ENDOR of MCR(red1) and MCR(ox1).	Nitrogen	159-167	nuclear receptor subfamily 3 group C member 2	Homo sapiens	90-93
11878988-3	2002	Upon freezing in a liquid N(2) bath, the colorless, nonluminescent solutions of [Au[C(NHMe)(2)](2)](PF(6)) x 0.5(acetone) become intensely luminescent.	Nitrogen	26-30	sperm associated antigen 17	Homo sapiens	100-105
11857580-0	2002	Evidence for an N-glycosylation polymorphism of arylsulfatase a predisposing to alcoholism in Koreans.	Nitrogen	16-17	arylsulfatase A	Homo sapiens	48-63
11857580-1	2002	This study investigated the possible effect of the pseudodeficient N-glycosylation polymorphism of the arylsulfatase A (ASA) gene on alcohol dependence among Koreans.	Nitrogen	67-68	arylsulfatase A	Homo sapiens	103-118
11857580-1	2002	This study investigated the possible effect of the pseudodeficient N-glycosylation polymorphism of the arylsulfatase A (ASA) gene on alcohol dependence among Koreans.	Nitrogen	67-68	arylsulfatase A	Homo sapiens	120-123
11857580-2	2002	Alcoholic patients (N=123) were more likely than control subjects to be heterozygous or homozygous for the ASA pseudodeficient N-glycosylation site (36% of alcoholics versus 20% of controls; P&lt;0.01).	Nitrogen	20-21	arylsulfatase A	Homo sapiens	107-110
11857580-3	2002	Among these 123 alcoholic patients, 42 alcoholics were heterozygous and two were homozygous for the ASA pseudodeficient N-glycosylation polymorphism.	Nitrogen	120-121	arylsulfatase A	Homo sapiens	100-103
11857580-4	2002	This result provides evidence that the ASA pseudodeficient N-glycosylation site allele increases the risk of alcohol dependence within a Korean population.	Nitrogen	59-60	arylsulfatase A	Homo sapiens	39-42
11414817-9	2001	X-band spectra of these cryoreduced samples, and of conventionally prepared MCR(red1) and MCR(ox1), all show resolved hyperfine splitting from four equivalent nitrogen ligands with coupling constants in agreement with those determined in previous EPR studies and from (14)N ENDOR of MCR(red1) and MCR(ox1).	Nitrogen	159-167	nuclear receptor subfamily 3 group C member 2	Homo sapiens	90-93
11414817-9	2001	X-band spectra of these cryoreduced samples, and of conventionally prepared MCR(red1) and MCR(ox1), all show resolved hyperfine splitting from four equivalent nitrogen ligands with coupling constants in agreement with those determined in previous EPR studies and from (14)N ENDOR of MCR(red1) and MCR(ox1).	Nitrogen	159-167	nuclear receptor subfamily 3 group C member 2	Homo sapiens	90-93
11895865-3	2002	The gene expression of CYP3A subfamily enzymes, especially CYP3A1, responsible for not only detoxification (N-demethylation) but also activation (alpha-hydroxylation) of tamoxifen, was increased by the tamoxifen treatments for 2 and 12 weeks, whereas after the 52 week treatment, the expression in the induced nodules returned to the control level.	Nitrogen	108-109	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	59-65
23782689-3	2013	KOR1 is a membrane-anchored endo-beta1,4-glucanase and contains eight potential N-glycosylation sites in its extracellular domain.	Nitrogen	80-81	glycosyl hydrolase 9A1	Arabidopsis thaliana	0-4
11861807-2	2002	Novel arvanil derivatives prepared by N-methylation, replacement of the amide with urea and thiourea moieties, and manipulation of the vanillyl group were evaluated for their ability to bind/activate CB1 receptors, activate VR1 receptors, inhibit the AMT and fatty acid amide hydrolase (FAAH), and produce cannabimimetic effects in mice.	Nitrogen	0-1	cannabinoid receptor 1 (brain)	Mus musculus	200-203
11396966-0	2001	Differential N-demethylation of l-alpha-acetylmethadol (LAAM) and norLAAM by cytochrome P450s 2B6, 2C18, and 3A4.	Nitrogen	13-14	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	77-103
11278508-3	2001	Because TAT1 accepted N-methyl- and N-acetyl-derivatives of aromatic amino acids but did not accept their methylesters, it is proposed that TAT1 recognizes amino acid substrates as anions.	Nitrogen	22-23	solute carrier family 16 member 10	Rattus norvegicus	8-12
11278508-3	2001	Because TAT1 accepted N-methyl- and N-acetyl-derivatives of aromatic amino acids but did not accept their methylesters, it is proposed that TAT1 recognizes amino acid substrates as anions.	Nitrogen	22-23	solute carrier family 16 member 10	Rattus norvegicus	140-144
23782689-4	2013	Here, we expressed A. thaliana KOR1 as a soluble, enzymatically active protein in insect cells and analyzed its N-glycosylation state.	Nitrogen	112-113	glycosyl hydrolase 9A1	Arabidopsis thaliana	31-35
11805197-9	2002	Docking of AQ into the active site homology models of the CYP2C isoforms showed favorable interactions with CYP2C8, which supported the likelihood of an N-desethylation reaction.	Nitrogen	153-154	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	108-114
23782689-11	2013	In summary, our data indicate that utilization of several N-glycosylation sites is important for KOR1 activity, whereas the structure of the attached N-glycans is not critical.	Nitrogen	58-59	glycosyl hydrolase 9A1	Arabidopsis thaliana	97-101
23825019-9	2013	TUSC3 is thought to encode a subunit of the endoplasmic reticulum-bound oligosaccharyltranferase complex that catalyzes a pivotal step in the protein N-glycosylation process.	Nitrogen	150-151	tumor suppressor candidate 3	Homo sapiens	0-5
11786016-0	2002	Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity.	Nitrogen	62-63	islet amyloid polypeptide	Homo sapiens	75-79
11786016-0	2002	Structure-based design and study of non-amyloidogenic, double N-methylated IAPP amyloid core sequences as inhibitors of IAPP amyloid formation and cytotoxicity.	Nitrogen	62-63	islet amyloid polypeptide	Homo sapiens	120-124
11450138-4	2001	N-type glycosylation of gp83 and gp78 was shown using tunicamicin.	Nitrogen	0-1	ADAM metallopeptidase domain 7	Homo sapiens	24-28
11308259-7	2001	Coexistence of N-SYT and I-SYT (both fused with SSX) was detected in a series of 59 SSs (35 monophasic and 24 biphasic) and in a SS cell line.	Nitrogen	15-16	synaptotagmin 1	Homo sapiens	17-20
11747548-3	2002	RESULTS: For cells irradiated with high LET nitrogen ions, there was an increase in the fast half-time from approximately 5 min for fragments &lt; 400 kbp to 10 min when all fragments &lt; 5.7 Mbp were measured.	Nitrogen	44-52	myelin basic protein	Homo sapiens	193-196
23718681-3	2013	In the present study, we identified co- and post-translational consensus sites in the KCNE family of K+ channel regulatory subunits to uncover three determinants that favour co-translational N-glycosylation kinetics of type I transmembrane peptides which lack a cleavable signal sequence: threonine-containing consensus sites (NXT), multiple N-terminal consensus sites and long C-termini.	Nitrogen	88-89	nuclear transport factor 2 like export factor 1	Homo sapiens	327-330
12387936-3	2002	Our goal was to develop a bioassay to detect N-alkylPPs formed following interaction of porphyrinogenic xenobiotics with rat liver microsomal CYP.	Nitrogen	45-46	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	142-145
11581260-1	2001	Nitrogen-containing bisphosphonate drugs inhibit bone resorption by inhibiting FPP synthase and thereby preventing the synthesis of isoprenoid lipids required for protein prenylation in bone-resorbing osteoclasts.	Nitrogen	0-8	farnesyl diphosphate synthetase	Mus musculus	79-91
11361134-7	2001	Therefore mutant proteins in which the N-glycosylation sites were eliminated (Asn --&gt; Gln in mouse MDR3 Pgp, Asn --&gt; Gln or Ala in human MDR1 Pgp) were expressed in P. pastoris and purified to homogeneity.	Nitrogen	39-40	ATP-binding cassette, sub-family B (MDR/TAP), member 1A	Mus musculus	102-106
11388472-10	2001	As compared with the placebo group, urinary cross-linked N-teleopeptides of type-I collagen/creatinine and deoxypyridinoline/creatinine were significantly decreased in the MBP group (p &lt; 0.05), while no significant differences between the two groups were observed in serum osteocalcin and bone-specific alkaline phosphatase concentrations.	Nitrogen	57-58	myelin basic protein	Homo sapiens	172-175
11720502-3	2001	The nitrogen adsorption and desorption analyses of this material exhibit a slight decrease of BET surface area from 580 m(2) g(-1) to 467 m(2) g(-1) and a concomitant decrease in pore size and volume from 28 A and 0.500 cm(3) g(-1) to 25 A and 0.363 cm(3) g(-1), respectively.	Nitrogen	4-12	delta/notch like EGF repeat containing	Homo sapiens	94-97
23743421-5	2013	Comments were made on the role of SNO complex for the interactions between sulfur, nitrogen and carbon metabolisms in anaerobic digestion.	Nitrogen	83-91	strawberry notch homolog 1	Homo sapiens	34-37
11724920-7	2001	The demonstration that Gcn4p affects transcription of more than 500 genes and that the recombinationally "hottest" ORFs tend to be Gcn4p-regulated suggest that the metabolic state of a cell, especially with respect to nitrogen metabolism, is a determinant of recombination rates.	Nitrogen	218-226	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	131-136
11244061-5	2001	S. pombe uses D-alanine as a sole nitrogen source, but deletion of the alr1(+) gene resulted in retarded growth on the same medium.	Nitrogen	34-42	Mg(2+) transporter ALR1	Saccharomyces cerevisiae S288C	71-75
11244061-9	2001	However, heterologous expression of the alr1(+) gene enabled S. cerevisiae to grow efficiently on D-alanine as a sole nitrogen source.	Nitrogen	118-126	Mg(2+) transporter ALR1	Saccharomyces cerevisiae S288C	40-44
11244074-0	2001	TOR modulates GCN4-dependent expression of genes turned on by nitrogen limitation.	Nitrogen	62-70	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	14-18
11244074-4	2001	The results presented in this paper indicate that GCN4 plays a role in the rapamycin-sensitive signaling pathway, regulating the expression of genes involved in the utilization of poor nitrogen sources, a previously unrecognized role for Gcn4p, and that the TOR pathway controls GCN4 activity by regulating the translation of GCN4 mRNA.	Nitrogen	185-193	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	50-54
11389756-1	2001	Regulation of root N uptake by whole-plant signalling of N status was investigated at the molecular level in Arabidopsis thaliana plants through expression analysis of AtNrt2.1 and AtAmt1.1.	Nitrogen	19-20	ammonium transporter 1;1	Arabidopsis thaliana	181-189
23755884-2	2013	A co-crystal structure analysis of imidazo[1,2-b]pyridazine derivative 2 with VEGFR2 revealed that the N1-nitrogen of imidazo[1,2-b]pyridazine core interacts with the backbone NH group of Cys919.	Nitrogen	106-114	kinase insert domain protein receptor	Mus musculus	78-84
11389756-1	2001	Regulation of root N uptake by whole-plant signalling of N status was investigated at the molecular level in Arabidopsis thaliana plants through expression analysis of AtNrt2.1 and AtAmt1.1.	Nitrogen	57-58	ammonium transporter 1;1	Arabidopsis thaliana	181-189
11730893-8	2001	It is suggested that PrP(C) is a normal Cu-dependent cuproglycoprotein of unknown function that may have a role in facilitating normal nitrogen monoxide- or carbon monoxide-mediated biochemistry.	Nitrogen	135-143	prion protein	Mus musculus	21-27
23643873-3	2013	Sequence analysis reveals that ten cysteines in the extracellular immunoglobulin-like (Ig-like) domains of EcM-CSFR are conserved in fish and mammals, its nine possible N-glycosylation sites are conserved in fish but not mammals, 7 of 8 identified mammal M-CSFR intracellular autophosphorylation tyrosine sites was found in EcM-CSFR.	Nitrogen	169-170	colony stimulating factor 1 receptor	Homo sapiens	111-115
11672902-0	2001	Enhanced immunogenicity of a human immunodeficiency virus type 1 env DNA vaccine by manipulating N-glycosylation signals.	Nitrogen	70-71	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	65-68
11261974-2	2001	Sapphyrins form monometallic complexes with coordination of one imine and amine type nitrogens of the bipyrrole unit in an eta2 fashion.	Nitrogen	85-94	DNA polymerase iota	Homo sapiens	123-127
11096087-7	2001	We show that nitrogen starvation or rapamycin treatment rapidly causes a more than 20-fold induction of APG14.	Nitrogen	13-21	Atg14p	Saccharomyces cerevisiae S288C	104-109
11096087-9	2001	However, overexpression of APG14 led to only a slight increase in autophagy in nitrogen-rich medium.	Nitrogen	79-87	Atg14p	Saccharomyces cerevisiae S288C	27-32
23503728-3	2013	In the present study, we looked at the role of asparagine (N)-linked glycosylation on human Cav3.2 T-type channel expression and function.	Nitrogen	58-61	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	92-98
11180979-1	2001	Acylpeptide hydrolase removes the N -acetylated amino acids from the peptide substrates but not from intact proteins.	Nitrogen	34-35	acylaminoacyl-peptide hydrolase	Bos taurus	0-21
11687605-0	2001	A novel Rtg2p activity regulates nitrogen catabolism in yeast.	Nitrogen	33-41	Rtg2p	Saccharomyces cerevisiae S288C	8-13
11687605-7	2001	These characteristics suggest that Rtg2p acts in the upstream part of the nitrogen catabolism regulation pathway.	Nitrogen	74-82	Rtg2p	Saccharomyces cerevisiae S288C	35-40
23503728-4	2013	Manipulation of N-glycans on cells expressing a recombinant Cav3.2 channel revealed that N-linked glycosylation is critical for proper functional expression of the channel.	Nitrogen	16-17	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	60-66
11179447-7	2001	melanogaster SERT chimera studies implicated the first two SERT transmembrane domains (TMDs) in the potency of the indole nitrogen-substituted compounds N-isopropyltryptamine (NIT), 5-methoxy-N-isopropyltryptamine (5-MNIT), and the 7-substituted compound 7-benzyloxytryptamine (7BT).	Nitrogen	122-130	Serotonin transporter	Drosophila melanogaster	13-17
23503728-5	2013	Using site-directed mutagenesis to disrupt the canonical N-linked glycosylation sites of Cav3.2 channel, we show that glycosylation at asparagine N192 is critical for channel expression at the surface, whereas glycosylation at asparagine N1466 controls channel activity.	Nitrogen	57-58	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	89-95
11595658-0	2001	N-glycosylation of CRF receptor type 1 is important for its ligand-specific interaction.	Nitrogen	0-1	corticotropin releasing hormone receptor 1	Homo sapiens	19-38
11595658-1	2001	The corticotropin-releasing factor (CRF) receptor type 1 (CRFR1) contains five potential N-glycosylation sites: N38, N45, N78, N90, and N98.	Nitrogen	89-90	corticotropin releasing hormone receptor 1	Homo sapiens	4-56
23503728-6	2013	Moreover, we demonstrate that N-linked glycosylation of Cav3.2 not only controls surface expression and activity of the channel but also underlies glucose-dependent potentiation of T-type Ca(2+) current.	Nitrogen	30-31	calcium voltage-gated channel subunit alpha1 H	Homo sapiens	56-62
11595658-1	2001	The corticotropin-releasing factor (CRF) receptor type 1 (CRFR1) contains five potential N-glycosylation sites: N38, N45, N78, N90, and N98.	Nitrogen	89-90	corticotropin releasing hormone receptor 1	Homo sapiens	58-63
11725960-8	2001	In addition, microsomes containing cDNA-expressed FMO1, a major isoform in human kidney, mainly catalyzed N-oxidation of SNI-2011, but microsomes containing FMO3, a major isoform in adult human liver, did not.	Nitrogen	37-38	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	50-54
11237689-4	2001	We show that baculovirus-insect cell-expressed FGFR4(ed) is glycosylated on three (N88, N234, and N266) of the six possible N-glycosylation sites but is not O-glycosylated.	Nitrogen	83-84	fibroblast growth factor receptor 4	Homo sapiens	47-52
23922826-6	2013	Although no significant differences were revealed in renal morphology and function between Osx heterozygotes and wild-type under normoxic conditions, recovery of kidneys after ischemic damage was remarkably delayed in Osx heterozygotes, as indicated by elevated blood urea nitrogen and creatinine levels, and by morphological alterations consistent with acute tubular necrosis.	Nitrogen	273-281	Sp7 transcription factor	Homo sapiens	218-221
11553022-4	2001	The Mn-SOD mRNA levels were markedly increased after exposure to nitrogen gas for 5 min.	Nitrogen	65-73	superoxide dismutase 2	Homo sapiens	4-10
23935844-5	2013	Compared with vector-MSCs injected mice, the hKLK1-MSCs treated mice showed significantly reduced proteinuria, blood urea nitrogen (BUN) and ameliorated renal pathology.	Nitrogen	122-130	kallikrein 1	Homo sapiens	45-50
11516162-3	2001	A mouse DAF CCP1-4 mutant protein in which its two potential N-glycosylation sites were deleted by changing Asn(187) and Asn(262) to Gln was also produced.	Nitrogen	61-62	granzyme B	Mus musculus	12-18
23740867-0	2013	Arsa-diazonium salts with an arsenic-nitrogen triple bond.	Nitrogen	37-45	arylsulfatase A	Homo sapiens	0-4
11483736-5	2001	N-myristoylation of Gag was necessary for association with barges.	Nitrogen	0-1	Pr55(Gag)	Human immunodeficiency virus 1	20-23
23542778-8	2013	As in mammals, chicken MTP is localized to the endoplasmic reticulum as revealed by indirect immunofluorescence and by the fact that its N-linked oligosaccharide moiety remains sensitive to endoglycosidase H. Endogenous, enzymatically active MTP is also expressed in an estrogen receptor-expressing chicken hepatoma cell line that secretes apolipoprotein B-containing lipoproteins.	Nitrogen	137-138	microsomal triglyceride transfer protein	Gallus gallus	23-26
11408486-2	2001	When nitrogen is limiting, Gln3p and Gat1p are concentrated in the nucleus where they bind GATA sequences upstream of nitrogen catabolite repression (NCR)-sensitive genes and activate their transcription.	Nitrogen	5-13	Gat1p	Saccharomyces cerevisiae S288C	37-42
11408486-2	2001	When nitrogen is limiting, Gln3p and Gat1p are concentrated in the nucleus where they bind GATA sequences upstream of nitrogen catabolite repression (NCR)-sensitive genes and activate their transcription.	Nitrogen	118-126	Gat1p	Saccharomyces cerevisiae S288C	37-42
23615730-1	2013	Reaction of SnF2 in MeOH with the appropriate neutral N- or O-donor ligands produces [SnF(2,2"-bipy)]2SnF6, [SnF(1,10-phen)]2SnF4 and [SnF2(L)] L = Me3PO, dmso or pyNO).	Nitrogen	54-55	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	12-16
11493051-8	2001	On the basis of this comparison, we provide evidence that C-N bond formation at the C-6 position, leading to N-aryl 2"-deoxyadenosine analogues, is more sensitive to the ligand used, whereas C-C bond-forming reactions at the same position are not.	Nitrogen	60-61	complement C6	Homo sapiens	84-87
23550066-0	2013	The CYP2B6*6 allele significantly alters the N-demethylation of ketamine enantiomers in vitro.	Nitrogen	45-46	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	4-10
11526439-5	2001	Here we show that N-terminal phosphorylation of c-Jun, the other main partner of c-Fos in induced AP-1 complexes is not required for programmed cell death during retinal development in vivo and is also dispensable for photoreceptor apoptosis induced by the exogenous stimuli "excessive light" and N-nitroso-N-methylurea (MNU).	Nitrogen	18-19	jun proto-oncogene	Mus musculus	48-53
23651256-2	2013	ARO9 and ARO10 are also under the control of nitrogen catabolite repression, but the direct roles for GATA factors, Gat1 and Gln3, in this regulation have not yet been elucidated.	Nitrogen	45-53	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	9-14
11526439-5	2001	Here we show that N-terminal phosphorylation of c-Jun, the other main partner of c-Fos in induced AP-1 complexes is not required for programmed cell death during retinal development in vivo and is also dispensable for photoreceptor apoptosis induced by the exogenous stimuli "excessive light" and N-nitroso-N-methylurea (MNU).	Nitrogen	18-19	jun proto-oncogene	Mus musculus	98-102
11356835-0	2001	Repression of GCN4 mRNA translation by nitrogen starvation in Saccharomyces cerevisiae.	Nitrogen	39-47	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	14-18
11356835-4	2001	Nitrogen starvation increases GCN4 transcription but efficiently represses expression of both a synthetic GCRE6::lacZ reporter gene and the natural amino acid biosynthetic gene ARO4.	Nitrogen	0-8	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	30-34
23714211-3	2013	Intercellular adhesion molecule-2 (ICAM-2), a member of the immunoglobulin superfamily of CAMs, has six N-linked glycosylation sites at amino acids (asparagines) 47, 82, 105, 153, 178 and 187.	Nitrogen	104-105	intercellular adhesion molecule 2	Mus musculus	0-33
11356835-4	2001	Nitrogen starvation increases GCN4 transcription but efficiently represses expression of both a synthetic GCRE6::lacZ reporter gene and the natural amino acid biosynthetic gene ARO4.	Nitrogen	0-8	3-deoxy-7-phosphoheptulonate synthase ARO4	Saccharomyces cerevisiae S288C	177-181
11356835-5	2001	Repression of Gcn4p-regulated transcription by nitrogen starvation is independent of the ammonium sensing systems that include Mep2p and Gpa2p or Ure2p and Gln3p but depends on the four upstream open reading frames in the GCN4 mRNA leader sequence.	Nitrogen	47-55	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	14-19
11356835-5	2001	Repression of Gcn4p-regulated transcription by nitrogen starvation is independent of the ammonium sensing systems that include Mep2p and Gpa2p or Ure2p and Gln3p but depends on the four upstream open reading frames in the GCN4 mRNA leader sequence.	Nitrogen	47-55	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	222-226
11356835-6	2001	Efficient translation of GCN4 mRNA is completely blocked by nitrogen starvation, even when cells are simultaneously starved for amino acids and eukaryotic initiation factor-2 alpha is fully phosphorylated by Gcn2p.	Nitrogen	60-68	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	25-29
11356835-7	2001	Our data suggest that nitrogen starvation regulates translation of GCN4 by a novel mechanism that involves the four upstream open reading frames but that still acts independently of eukaryotic initiation factor-2 alpha phosphorylation by Gcn2p.	Nitrogen	22-30	amino acid starvation-responsive transcription factor GCN4	Saccharomyces cerevisiae S288C	67-71
23714211-3	2013	Intercellular adhesion molecule-2 (ICAM-2), a member of the immunoglobulin superfamily of CAMs, has six N-linked glycosylation sites at amino acids (asparagines) 47, 82, 105, 153, 178 and 187.	Nitrogen	104-105	intercellular adhesion molecule 2	Mus musculus	35-41
11390601-0	2001	N-linked glycosylation sites adjacent to and within the V1/V2 and the V3 loops of dualtropic human immunodeficiency virus type 1 isolate DH12 gp120 affect coreceptor usage and cellular tropism.	Nitrogen	0-1	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	142-147
11259430-5	2001	Binding assays revealed that p40 recognizes N-acetyl groups in association with a pyranose ring and that p50 recognizes N-acetylglucosamine alone.	Nitrogen	44-45	interleukin 9	Homo sapiens	29-32
11353758-0	2001	Involvement of CYP2B6 in n-demethylation of ketamine in human liver microsomes.	Nitrogen	1-2	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	15-21
11353758-5	2001	Among the 12 cDNA-expressed CYP enzymes examined, CYP2B6, CYP2C9, and CYP3A4 showed high activities for the N-demethylation of both enantiomers at the substrate concentration of 1 mM.	Nitrogen	15-16	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	50-56
23737721-4	2013	The BET surface area of the activated carbon is investigated using N2 adsorption at 77 K with selected temperatures of 500, 600, and 700 C. These pyrolysis conditions for preparing the activated carbons are found to yield higher BET surface area at a pyrolysis temperature of 700 C compared to selected commercial activated carbon.	Nitrogen	67-69	delta/notch like EGF repeat containing	Homo sapiens	4-7
11353758-6	2001	CYP2B6 had the lowest K(m) value for the N-demethylation of (R)- and (S)-ketamine (74 and 44 microM, respectively).	Nitrogen	41-42	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-6
11353758-7	2001	Also, the intrinsic clearance (CL(int): V(max)/K(m)) of CYP2B6 for the N-demethylation of both enantiomers were 7 to 13 times higher than those of CYP2C9 and CYP3A4.	Nitrogen	71-72	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	56-62
11353758-11	2001	CYP2B6 mainly mediates the N-demethylation of (R)- and (S)-ketamine in human liver microsomes at therapeutic concentrations (5 microM).	Nitrogen	27-28	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	0-6
23454304-8	2013	We used this combination of deglycosylation and complementary protease digest to identify changes in the yeast cell wall proteome caused by lack of the Alg3p protein, a key component of the biosynthetic pathway of protein N-glycosylation.	Nitrogen	222-223	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	152-157
11340165-6	2001	We found that Clb1, Clb2, and Clb5 cyclin levels are reduced in nitrogen-limited chemostat cultures compared to levels in rich-medium cultures, whereas the Xbp1 transcriptional repressor is highly induced under these conditions.	Nitrogen	64-72	B-type cyclin CLB1	Saccharomyces cerevisiae S288C	14-18
11399819-15	2001	CONCLUSIONS: NA2 expression is affected by polymorphisms in FcgammaRIIIB 227 and FcgammaRIIIB 277, both of which are involved in an FcgammaRIIIb N-glycosylation site.	Nitrogen	2-3	Fc gamma receptor IIIb	Homo sapiens	60-72
23756390-8	2013	Decreased COX-2 after GS-HCl was caused by N-glycosylation inhibition as much as tunicamycin.	Nitrogen	43-44	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	10-15
11399819-15	2001	CONCLUSIONS: NA2 expression is affected by polymorphisms in FcgammaRIIIB 227 and FcgammaRIIIB 277, both of which are involved in an FcgammaRIIIb N-glycosylation site.	Nitrogen	2-3	Fc gamma receptor IIIb	Homo sapiens	81-93
11399819-15	2001	CONCLUSIONS: NA2 expression is affected by polymorphisms in FcgammaRIIIB 227 and FcgammaRIIIB 277, both of which are involved in an FcgammaRIIIb N-glycosylation site.	Nitrogen	2-3	Fc gamma receptor IIIb	Homo sapiens	132-144
23268448-7	2013	In addition, we studied the yeast filamentous response to nitrogen stress by profiling changes in transcript levels upon deletion of two key filamentous growth transcription factors, FLO8 and MSS11.	Nitrogen	58-66	FLO8	Saccharomyces cerevisiae S288C	183-187
11327897-12	2001	Nitrogen adsorption (BET) indicates a surface area of up to 30 m(2)/g using a Langmuir model for gamma-Mo(2)N produced by a metathesis reaction at ambient pressure.	Nitrogen	0-8	delta/notch like EGF repeat containing	Homo sapiens	21-24
22789031-8	2013	We conclude that ASN2 is essential for nitrogen assimilation, distribution and remobilization (via the phloem) within the plant.	Nitrogen	39-47	asparagine synthetase 2	Arabidopsis thaliana	17-21
11278567-0	2001	N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization.	Nitrogen	0-1	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	41-46
23201271-0	2013	Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.	Nitrogen	39-40	NEDD8 ubiquitin like modifier	Homo sapiens	114-119
11259560-4	2001	For the pathways of N-demethylation (mediated by CYPs 1A2, 2B6, 2C8, 2C9, 2C19, 2D6, and 3A4) and E-10 hydroxylation (mediated by CYPs 2B6, 2D6, and 3A4), the model-predicted biotransformation rates in microsomes from a panel of 12 human livers determined from enzyme kinetic parameters of the recombinant CYPs were similar to, and correlated with the observed rates.	Nitrogen	20-21	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	130-143
22120669-6	2013	Introduction of a methyl or carboxylate group on the carbon adjacent to the side-chain amide nitrogen in L-gamma-glutamylamine substrates resulted in a dramatic decrease in substrate properties for gGACT thus providing an explanation of why gGACT does not act on L-gamma-glutamyl amino acids except for L-gamma-glutamylglycine.	Nitrogen	93-101	gamma-glutamylaminecyclotransferase	Oryctolagus cuniculus	198-203
11304570-6	2001	After administration of kappa-carrageenan, blood urea nitrogen of Synd4(-/-) mice was significantly higher than that of Synd4(+/+) mice.	Nitrogen	54-62	syndecan 4	Mus musculus	66-71
22120669-6	2013	Introduction of a methyl or carboxylate group on the carbon adjacent to the side-chain amide nitrogen in L-gamma-glutamylamine substrates resulted in a dramatic decrease in substrate properties for gGACT thus providing an explanation of why gGACT does not act on L-gamma-glutamyl amino acids except for L-gamma-glutamylglycine.	Nitrogen	93-101	gamma-glutamylaminecyclotransferase	Oryctolagus cuniculus	241-246
11380948-3	2001	FcgammaRIIIb-NA2-specific monoclonal antibodies (GRM1 and PEN1) did not bind to mutant neutrophils, which lack an N-linked glycosylation site.	Nitrogen	13-14	Fc gamma receptor IIIb	Homo sapiens	0-12
11380948-3	2001	FcgammaRIIIb-NA2-specific monoclonal antibodies (GRM1 and PEN1) did not bind to mutant neutrophils, which lack an N-linked glycosylation site.	Nitrogen	13-14	glutamate metabotropic receptor 1	Homo sapiens	49-53
22120669-7	2013	Placement of substituents on carbons further removed from the side-chain amide nitrogen in L-gamma-glutamylamines restored activity for gGACT, and L-gamma-glutamylneohexylamine 19 had a higher specificity constant (k(cat) /K(m)) than 1.	Nitrogen	79-87	gamma-glutamylaminecyclotransferase	Oryctolagus cuniculus	136-141
24378464-7	2013	The positive ion complexes of Zn(II) and Cu(II) were both shown to coordinate via the two imidazole nitrogens of His1 and His5 and either the oxygen of the backbone carbonyl of Cys6 or the oxygen of the C-terminal, respectively.	Nitrogen	100-109	viral integration site 1	Homo sapiens	113-117
11401446-3	2001	The conserved extracellular domain features found in rat, mouse, and human PV-1 protein are four N-glycosylation sites, two coiled-coil domains, a proline-rich region, and even cysteine spacing.	Nitrogen	97-98	plasmalemma vesicle associated protein	Homo sapiens	75-79
11174017-18	2001	In conclusion, (1) n-octanoylation of Ghrs and the shorter form hGhr18 is essential for the direct pituitary GH-releasing effect of this new family of endogenous GHSs; (2) only the longer forms are active in vivo and (3) inhibition of SRIH release appears involved in the mechanism of Ghr action.	Nitrogen	1-2	ghrelin and obestatin prepropeptide	Rattus norvegicus	38-41
11118640-2	2000	To further explore the effect of aberrant (rather than absent) N-linked glycosylation of the insulin receptor, we examined the relationship of processing to function.	Nitrogen	63-64	insulin receptor	Homo sapiens	93-109
11077038-1	2000	The alkylating agent, nitrogen mustard (HN2), is thought to cause apoptosis through production of free oxygen radicals.	Nitrogen	22-30	MT-RNR2 like 2 (pseudogene)	Homo sapiens	40-43
11225098-1	2001	A series of (eta 6-arene)OsII complexes containing the saturated nitrogen donor ligands tmtacn, tacn, and NH3 are prepared and characterized.	Nitrogen	65-73	endothelin receptor type A	Homo sapiens	13-16
11407536-12	2001	However, there was notable stereoselectivity in the N-dealkylation by dog CYP3A12.	Nitrogen	52-53	cytochrome P450 3A12	Canis lupus familiaris	74-81
23984654-10	2013	Higher ratios for N2 can be attributed to the lower resistance that allowed higher aerosol flow through the filter media and captured more negatively charged particles to produce lesser Cin or greater Cout/Cin ratio.	Nitrogen	18-20	pyridoxal phosphatase	Homo sapiens	186-189
11435687-6	2001	However, unlike most of the other proteins containing stomatin-like domains, the predicted STOML2 polypeptide does not contain a transmembrane region although the presence of N-myristoylation sites suggest that it has the potential to be membrane-associated.	Nitrogen	175-176	stomatin like 2	Homo sapiens	91-97
11108295-2	2000	In vitro studies indicate that the clinically used nitrogen-containing bisphosphonates (N-BPs) such as alendronate (ALN), risedronate (RIS) and ibandronate (IBA) suppress bone resorption via inhibition of the mevalonate pathway enzyme farnesyl diphosphate (FPP) synthase in osteoclasts (Ocs).	Nitrogen	51-59	farnesyl diphosphate synthase	Rattus norvegicus	235-270
11180637-0	2000	Identification of the nitrogen-based blister agents bis(2-chloroethyl)methylamine (HN-2) and tris(2-chloroethyl)amine (HN-3) and their hydrolysis products on soil using ion trap secondary ion mass spectrometry.	Nitrogen	22-30	MT-RNR2 like 2 (pseudogene)	Homo sapiens	83-87
23984654-10	2013	Higher ratios for N2 can be attributed to the lower resistance that allowed higher aerosol flow through the filter media and captured more negatively charged particles to produce lesser Cin or greater Cout/Cin ratio.	Nitrogen	18-20	pyridoxal phosphatase	Homo sapiens	206-209
11202731-9	2001	It has been found that these processes were able to remove nitrogen content almost completely and simultaneously, the removal of organic matter (expressed as BOD5 and COD), color and turbidity were sufficiently achieved.	Nitrogen	59-67	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	167-170
23199690-0	2013	Nitrogen and phosphorus interaction and cytokinin: responses of the primary root of Arabidopsis thaliana and the pdr1 mutant.	Nitrogen	0-8	pleiotropic drug resistance 1	Arabidopsis thaliana	113-117
11152942-3	2001	Nitrogen deprivation, and possibly other stresses, activate a MAP kinase cascade which has the transcription factor Ste12 as its final target.	Nitrogen	0-8	homeodomain family transcription factor STE12	Saccharomyces cerevisiae S288C	116-121
11064198-4	2000	The promoter region of glnA was subcloned into a beta-galactosidase fusion vector and the results suggested that NtrC positively regulates the glnA promoter in response to low nitrogen.	Nitrogen	176-184	type I glutamate--ammonia ligase	Herbaspirillum seropedicae	23-27
11064198-4	2000	The promoter region of glnA was subcloned into a beta-galactosidase fusion vector and the results suggested that NtrC positively regulates the glnA promoter in response to low nitrogen.	Nitrogen	176-184	type I glutamate--ammonia ligase	Herbaspirillum seropedicae	143-147
23468852-8	2013	In vivo, after renal IRI or a nephrotoxic dose of HgCl2 treatment, IL-20R1-deficient mice (the deficiency blocks IL-19 signaling) showed lower levels of blood urea nitrogen (BUN) in serum and less tubular damage than did wild-type mice.	Nitrogen	164-172	interleukin 20 receptor, alpha	Mus musculus	67-74
11089547-0	2000	Glut-1 translocation in FRTL-5 thyroid cells: role of phosphatidylinositol 3-kinase and N-glycosylation.	Nitrogen	88-89	solute carrier family 2 member 1	Rattus norvegicus	0-6
11089547-10	2000	To further elucidate mechanisms that regulate the translocation of Glut-1 to cell membrane, we extended this study to the role played by the N-glycosylation in the translocation and in the biological activity of Glut-1 in FRTL-5 cells.	Nitrogen	141-142	solute carrier family 2 member 1	Rattus norvegicus	212-218
11215633-4	2001	By annealing the SC1-treated surface in N2 gas at above 200 degrees C for 30 min, the oxide layer could not be scratched any more.	Nitrogen	40-42	transcription factor 19	Homo sapiens	17-20
11428641-1	2000	Sulfur mustard and nitrogen mustard (HN2) are reported to produce neurobehavioral and neuropathological changes in animals and humans, but the mechanisms are unknown.	Nitrogen	19-27	MT-RNR2 like 2 (pseudogene)	Homo sapiens	37-40
11114086-6	2000	Sterical hindrance caused by different substituents at the nitrogen atom of the beta-ethanolamine lateral chain of beta(2)-agonist molecules is mainly responsible for differences in the abundances of the derivatives obtained.	Nitrogen	59-67	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	115-121
23408955-1	2013	Alanine aminotransferase (AlaAT) has been studied in a variety of organisms due to the involvement of this enzyme in mammalian processes such as non-alcoholic hepatocellular damage, and in plant processes such as C4 photosynthesis, post-hypoxic stress response and nitrogen use efficiency.	Nitrogen	265-273	glutamic--pyruvic transaminase	Homo sapiens	0-24
11132853-10	2000	These data demonstrate the importance of mucin as a source of endogenous nitrogen and the impact of dietary protein content and origin on this flow.	Nitrogen	73-81	mucin 1, cell surface associated	Bos taurus	41-46
23408955-1	2013	Alanine aminotransferase (AlaAT) has been studied in a variety of organisms due to the involvement of this enzyme in mammalian processes such as non-alcoholic hepatocellular damage, and in plant processes such as C4 photosynthesis, post-hypoxic stress response and nitrogen use efficiency.	Nitrogen	265-273	glutamic--pyruvic transaminase	Homo sapiens	26-31
11027268-3	2000	The role of NER and recombination in the repair of ICLs induced by nitrogen mustard (HN2) was investigated using Chinese hamster ovary mutant cell lines.	Nitrogen	67-75	MT-RNR2 like 2 (pseudogene)	Homo sapiens	85-88
23408955-7	2013	Specifically, the differing kinetics of AlaAT enzymes and how this may alter the nitrogen use efficiency in plants is discussed.	Nitrogen	81-89	glutamic--pyruvic transaminase	Homo sapiens	40-45
11097841-2	2000	Transcription of IME1 is induced under starvation for nitrogen and glucose and in the presence of the MATa1 and MATalpha2 gene products.	Nitrogen	54-62	transcription factor IME1	Saccharomyces cerevisiae S288C	17-21
23592978-7	2013	In culture 2, replication was restored with deletion of the N139INN sequence, which ablates the overlapping Asn141-Asn142-Ser-Ser potential N-linked glycosylation sequons in V1, in conjunction with D601N in the DSR.	Nitrogen	60-61	immunoglobulin kappa variable 1-5	Homo sapiens	174-176
11027140-5	2000	On (1)H-(15)N HMQC NMR analysis of pol beta with LCA, the 8-kDa domain bound to LCA as a 1:1 complex with a dissociation constant (K(D)) of 1.56 mM.	Nitrogen	12-13	DNA polymerase beta	Homo sapiens	35-43
23202518-1	2012	The human cellular prion protein (PrP(C)) is a glycosylphosphatidylinositol (GPI) anchored membrane glycoprotein with two N-glycosylation sites at residues 181 and 197.	Nitrogen	122-123	prion protein	Mus musculus	34-40
11011097-3	2000	The deduced polypeptide of CABGLU which contains a C-terminal extension N-glycosylated at a single site characterized as typical structure of class I beta-1,3-glucanase has a high level of identity with tobacco basic beta-1,3-glucanase (77.4%), but only a moderate level of identity with tomato acidic beta-1,3-glucanase (42.6%).	Nitrogen	72-73	glucan endo-1,3-beta-glucosidase B	Solanum lycopersicum	150-168
11011097-3	2000	The deduced polypeptide of CABGLU which contains a C-terminal extension N-glycosylated at a single site characterized as typical structure of class I beta-1,3-glucanase has a high level of identity with tobacco basic beta-1,3-glucanase (77.4%), but only a moderate level of identity with tomato acidic beta-1,3-glucanase (42.6%).	Nitrogen	72-73	glucan endo-1,3-beta-glucosidase B	Solanum lycopersicum	217-235
11011100-5	2000	Measurements of nitrogen-assimilating enzyme activities of these fruits showed a decrease in glutamine synthetase (GS, EC 6.3.1.2) during fruit ripening and a concomitant increase in NADH-glutamate dehydrogenase (GDH, EC 1.4.1.3) and aspartate aminotransferase (EC 2.6.1.1) activities.	Nitrogen	16-24	glutamate dehydrogenase	Solanum lycopersicum	183-211
11011100-5	2000	Measurements of nitrogen-assimilating enzyme activities of these fruits showed a decrease in glutamine synthetase (GS, EC 6.3.1.2) during fruit ripening and a concomitant increase in NADH-glutamate dehydrogenase (GDH, EC 1.4.1.3) and aspartate aminotransferase (EC 2.6.1.1) activities.	Nitrogen	16-24	glutamate dehydrogenase	Solanum lycopersicum	213-216
11011146-4	2000	In this study, we showed that the synaptotagmin family is a type I membrane protein (N(lumen)/C(cytoplasm)) by introducing an artificial N-glycosylation site at the N-terminal domain, and systematically examined all the possible combinations of hetero-oligomerization among synaptotagmin family proteins (Syts I-XI).	Nitrogen	85-86	synaptotagmin 1	Homo sapiens	34-47
11011146-4	2000	In this study, we showed that the synaptotagmin family is a type I membrane protein (N(lumen)/C(cytoplasm)) by introducing an artificial N-glycosylation site at the N-terminal domain, and systematically examined all the possible combinations of hetero-oligomerization among synaptotagmin family proteins (Syts I-XI).	Nitrogen	85-86	synaptotagmin 1	Homo sapiens	274-287
10988254-0	2000	The C-terminal N-glycosylation sites of the human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, adn -VI) are necessary for the expression of full enzyme activity.	Nitrogen	15-16	complement factor D	Homo sapiens	112-115
11067926-4	2000	We demonstrate that the presence of untrimmed N-linked core glycans (Glc(3)Man(9)GlcNAc(2)) on the FcepsilonRI alpha-chain activates the ER quality control mechanism to retain this subunit in the ER, despite the presence of gamma-chains.	Nitrogen	46-47	Fc epsilon receptor Ia	Homo sapiens	99-116
11443278-5	2000	In contrast to OST48, ribophorin I and II contain, respectively, three or two potential N-glycosylation sites of the Asn-Xaa-Thr/Ser type; only one is found to function as the acceptor site in each protein.	Nitrogen	88-89	ribophorin I	Sus scrofa	22-41
11038189-1	2000	In yeast, assembly of exocytic soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor (SNARE) complexes between the secretory vesicle SNARE Sncp and the plasma membrane SNAREs Ssop and Sec9p occurs at a late stage of the exocytic reaction.	Nitrogen	39-40	Sec9p	Saccharomyces cerevisiae S288C	214-219
22940675-1	2012	Exocytosis of neurosecretory vesicles is mediated by the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins syntaxin-1, synaptobrevin and SNAP-25, with synaptotagmin functioning as the major Ca(2+) sensor for triggering membrane fusion.	Nitrogen	58-59	synaptosome associated protein 25	Bos taurus	174-181
10918058-8	2000	Since nitrate reductase has been shown to be inactivated by phosphorylation upon 14-3-3 binding, the present findings strongly suggest that WPK4 is the protein kinase responsible for controlling the nitrogen metabolic pathway, assembling the nitrate reductase and 14-3-3 complex through its phosphorylation specificity.	Nitrogen	199-207	CBL-interacting protein kinase 19	Triticum aestivum	140-144
11012666-6	2000	The full-length DPP8 cDNA codes for an 882-amino-acid protein that has about 27% identity and 51% similarity to DPPIV and FAP, but no transmembrane domain and no N-linked or O-linked glycosylation.	Nitrogen	23-24	fibroblast activation protein alpha	Homo sapiens	122-125
10975417-6	2000	Long storage periods (28 days) in liquid nitrogen results in a threefold decrease of P25b levels associated with cryopreserved versus fresh spermatozoa.	Nitrogen	41-49	tubulin polymerization promoting protein family member 2	Homo sapiens	85-89
22858633-0	2012	The SNARE protein SYP71 expressed in vascular tissues is involved in symbiotic nitrogen fixation in Lotus japonicus nodules.	Nitrogen	79-87	syntaxin of plants 71	Arabidopsis thaliana	18-23
11006339-0	2000	SOS3 function in plant salt tolerance requires N-myristoylation and calcium binding.	Nitrogen	47-48	Calcium-binding EF-hand family protein	Arabidopsis thaliana	0-4
10970800-0	2000	Requirement of N-glycosylation of the prostaglandin E2 receptor EP3beta for correct sorting to the plasma membrane but not for correct folding.	Nitrogen	15-16	epididymal protein 3B	Homo sapiens	64-71
10970800-4	2000	The current study analysed the role of the two N-glycosylation sites in the rat EP3beta-subtype PGE(2) receptor for protein folding and sorting.	Nitrogen	47-48	epididymal protein 3B	Homo sapiens	80-87
22828791-1	2012	Azotobacter                         chroococcum TRA2, an isolate of wheat rhizosphere displayed plant growth promoting attributes including indole acetic acid, HCN, siderophore production, solubilization of inorganic phosphate and fixation of atmospheric nitrogen.	Nitrogen	255-263	serine/arginine-rich splicing factor SR45a	Triticum aestivum	48-52
10989127-9	2000	A potential N-glycosylation site (site 1) with similar tripeptide patterns was observed at the same position in human plasma (HYAL1), human lysosomes (HYAL2) and in two newly reported hyaluronidases (HYAL4 and HYALP1).	Nitrogen	12-13	hyaluronidase 1	Homo sapiens	126-131
10926513-1	2000	The internal motions of the backbone nitrogen atoms of the kringle 1 domain of human plasminogen (K1(Pg)) were examined in the absence and presence of the ligand, epsilon-aminocaproic acid.	Nitrogen	37-45	keratin 1	Homo sapiens	98-104
10878382-0	2000	Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression.	Nitrogen	115-116	C-X-C motif chemokine receptor 2	Homo sapiens	63-87
10878382-6	2000	In addition, two other CXCR-2 variants of 38 and 40 kDa were found to occur exclusively intracellular and to carry N-glycosylations of high mannose or hybrid type.	Nitrogen	115-116	C-X-C motif chemokine receptor 2	Homo sapiens	23-29
22845020-7	2012	Furthermore, blood urea nitrogen (BUN) and plasma creatinine levels, indicative of nephrotoxicity, were also found to be significantly lesser for developed PLN formulation as compared to free drug and Fungizone while comparable to that of Fungisome.	Nitrogen	24-32	phospholamban	Homo sapiens	156-159
10799653-8	2000	The most important isozyme for this reaction appeared to be CYP2B6, the microsomal content of which was found to be strongly correlated to N-deethylation of MDE (r(s) = 0.90; P &lt; 0.001).	Nitrogen	139-140	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	60-66
10799523-0	2000	Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	85-90
11465080-2	2000	The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen (eg, hydroxyl or carboxylic acid groups), nitrogen (eg, amines), sulfur (eg, thiols), and carbon, with the formation of a beta-D-glucuronide product.	Nitrogen	241-249	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	4-31
11465080-2	2000	The UDP-glucuronosyltransferase (UGT) family catalyzes the glucuronidation of the glycosyl group of a nucleotide sugar to an acceptor compound (aglycone) at a nucleophilic functional group of oxygen (eg, hydroxyl or carboxylic acid groups), nitrogen (eg, amines), sulfur (eg, thiols), and carbon, with the formation of a beta-D-glucuronide product.	Nitrogen	241-249	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	33-36
11465082-3	2000	Human FMO3 N-oxygenates primary, secondary and tertiary amines whereas human FMO1 is only highly efficient at N-oxygenating tertiary amines.	Nitrogen	11-12	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	77-81
11007268-6	2000	Here, the selective and facile cyclization of N-chloroacetylated, C-cysteine amide peptides from the C4 domain of HIV-1 gp120 in LiCl/DMF solvent systems is demonstrated.	Nitrogen	46-47	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	120-125
11006339-11	2000	Together, these results strongly suggest that both N-myristoylation and calcium binding are required for SOS3 function in plant salt tolerance.	Nitrogen	51-52	Calcium-binding EF-hand family protein	Arabidopsis thaliana	105-109
10799523-1	2000	GATA family activators (Gln3p and Gat1p) and repressors (Dal80p and Deh1p) regulate nitrogen catabolite repression (NCR)-sensitive transcription in Saccharomyces cerevisiae presumably via their competitive binding to the GATA sequences upstream of NCR-sensitive genes.	Nitrogen	84-92	Gat1p	Saccharomyces cerevisiae S288C	34-39
10799523-1	2000	GATA family activators (Gln3p and Gat1p) and repressors (Dal80p and Deh1p) regulate nitrogen catabolite repression (NCR)-sensitive transcription in Saccharomyces cerevisiae presumably via their competitive binding to the GATA sequences upstream of NCR-sensitive genes.	Nitrogen	84-92	Gzf3p	Saccharomyces cerevisiae S288C	68-73
10799523-2	2000	Ure2p, which is not a GATA family member, inhibits Gln3p/Gat1p from functioning in the presence of good nitrogen sources.	Nitrogen	104-112	Gat1p	Saccharomyces cerevisiae S288C	57-62
10692561-0	2000	Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide.	Nitrogen	63-64	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	42-48
10692561-6	2000	Because CYP2B6 can make a significant contribution to human liver microsomal IFA N-dechloroethylation, but only a minor contribution to IFA 4-hydroxylation, the selective inhibition of hepatic CYP2B6 activity in individuals with a high hepatic CYP2B6 content may provide a useful approach to minimize the formation of therapeutically inactive but toxic N-dechloroethylated IFA metabolites.	Nitrogen	81-82	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	8-14
10740295-0	2000	The nitrogen physiology of the marine N2-fixing cyanobacteria Trichodesmium spp.	Nitrogen	4-12	histocompatibility minor 13	Homo sapiens	76-79
10740295-6	2000	Combined nitrogen is released from cells during periods of active growth and N2 fixation, and concomitantly taken up by Trichodesmium spp.	Nitrogen	9-17	histocompatibility minor 13	Homo sapiens	134-137
10920259-4	2000	The full-length MUC4 cDNA includes a leader sequence, a serine and threonine rich non-tandem repeat region, a central large tandem repeat domain containing 48 bp repetitive units, regions rich in potential N-glycosylation sites, two cysteine-rich domains, EGF-like domains, and a transmembrane domain.	Nitrogen	23-24	mucin 4, cell surface associated	Homo sapiens	16-20
22899766-5	2012	CysC levels strongly correlated with creatinine (r=0.73), blood urea nitrogen (r=0.70), and estimated glomerular filtration rate by the 4-variable modification of diet in renal disease equation (r=-0.62) (all P&lt;0.001).	Nitrogen	69-77	cystatin C	Homo sapiens	0-4
10891485-0	2000	Shared roles of yeast glycogen synthase kinase 3 family members in nitrogen-responsive phosphorylation of meiotic regulator Ume6p.	Nitrogen	67-75	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	124-129
10891485-2	2000	We show here that Ume6p, a subunit of the Ume6p-Ime1p meiotic transcriptional activator, undergoes increased phosphorylation in vivo in response to nitrogen limitation.	Nitrogen	148-156	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	18-23
10891485-2	2000	We show here that Ume6p, a subunit of the Ume6p-Ime1p meiotic transcriptional activator, undergoes increased phosphorylation in vivo in response to nitrogen limitation.	Nitrogen	148-156	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	42-47
10891485-2	2000	We show here that Ume6p, a subunit of the Ume6p-Ime1p meiotic transcriptional activator, undergoes increased phosphorylation in vivo in response to nitrogen limitation.	Nitrogen	148-156	transcription factor IME1	Saccharomyces cerevisiae S288C	48-53
10891485-7	2000	These findings argue that nitrogen limitation governs Rim11p/Mck1p-dependent phosphorylation of Ume6p, which in turn is required for Ume6p-Ime1p interaction and meiotic gene activation.	Nitrogen	26-34	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	96-101
10713140-3	2000	To probe the role that each N-glycosylation site plays in the synthesis of biologically active tyrosinase, we analyzed the calnexin mediated folding of tyrosinase N-glycosylation mutants.	Nitrogen	163-164	calnexin	Homo sapiens	123-131
10891485-7	2000	These findings argue that nitrogen limitation governs Rim11p/Mck1p-dependent phosphorylation of Ume6p, which in turn is required for Ume6p-Ime1p interaction and meiotic gene activation.	Nitrogen	26-34	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	133-138
22859506-1	2012	Lipochitin oligosaccharides called Nod factors function as primary rhizobial signal molecules triggering legumes to develop new plant organs: root nodules that host the bacteria as nitrogen-fixing bacteroids.	Nitrogen	181-189	atrophin 1	Homo sapiens	35-38
10891485-7	2000	These findings argue that nitrogen limitation governs Rim11p/Mck1p-dependent phosphorylation of Ume6p, which in turn is required for Ume6p-Ime1p interaction and meiotic gene activation.	Nitrogen	26-34	transcription factor IME1	Saccharomyces cerevisiae S288C	139-144
10861210-1	2000	The human erythrocyte anion exchanger (AE)1 (Band 3) contains a single complex N-linked oligosaccharide that is attached to Asn(642) in the fourth extracellular loop of this polytopic membrane protein, while other isoforms (AE2, AE3 and trout AE1) are N-glycosylated on the preceding extracellular loop.	Nitrogen	79-80	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	243-246
10861210-5	2000	Moving the N-glycosylation site to the preceding extracellular loop in an AE1 glycosylation mutant (N555) resulted in processing of the oligosaccharide and production of a complex form of AE1.	Nitrogen	11-12	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	74-77
10671487-3	2000	Unlike GLUT1-5, GLUTX1 has a short extracellular loop between transmembrane domain (TM) 1 and TM2 and a long extracellular loop between TM9 and TM10 that contains the only N-glycosylation site.	Nitrogen	172-173	solute carrier family 2 member 8	Homo sapiens	16-22
10673438-2	2000	Adenylosuccinate lyase is the only enzyme in this pathway to catalyze two separate reactions, enabling it to participate in the addition of a nitrogen at two different positions in adenosine monophosphate.	Nitrogen	142-150	adenylosuccinate lyase	Homo sapiens	0-22
10861210-5	2000	Moving the N-glycosylation site to the preceding extracellular loop in an AE1 glycosylation mutant (N555) resulted in processing of the oligosaccharide and production of a complex form of AE1.	Nitrogen	11-12	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	188-191
22571197-3	2012	Although N-linked glycosylation of TbetaRII was first demonstrated over a decade ago, it was unclear how this modification influenced TbetaRII biology.	Nitrogen	9-10	transforming growth factor beta receptor 2	Homo sapiens	35-43
10910977-7	2000	These in vivo and in vitro experiments suggest that in yeast cells Pkc1p may be involved in regulation of the N-glycosylation of proteins.	Nitrogen	110-111	protein kinase C	Saccharomyces cerevisiae S288C	67-72
10633045-4	2000	In each case, the nitrogen at position-1 of the quinazoline accepted a hydrogen bond from a backbone NH (CDK2, Leu-83; p38, Met-109) of the domain connector strand, and aromatic hydrogen atoms at C2 and C8 interacted with backbone carbonyl oxygen atoms of the peptide strand.	Nitrogen	18-26	cyclin dependent kinase 2	Homo sapiens	105-109
10717383-3	2000	We show here that three different strains deficient in either the Ku80 (xrs-6) or DNA-PKcs (V-3, scid) component of DNA-PK are markedly sensitive (3.5- to 5-fold) to a group of DNA cross-linking agents, the nitrogen mustards (NMs) (melphalan and mechlorethamine) as compared to their parental cell line.	Nitrogen	207-215	X-ray repair cross complementing 5	Homo sapiens	66-70
11294506-3	2000	Here we report a sensitive mapping strategy for profiling and analysing the N-glycosylation of gp160, based on chemical release of glycans, fluorescent labelling and HPLC analysis.	Nitrogen	76-77	glutamyl aminopeptidase	Homo sapiens	95-100
22571197-4	2012	In the present study, we show that inhibiting the N-linked glycosylation process successfully hinders binding of TGF-beta1 to TbetaRII and subsequently renders cells resistant to TGF-beta signalling.	Nitrogen	50-51	transforming growth factor beta receptor 2	Homo sapiens	126-134
22571197-6	2012	We demonstrate that defective N-linked glycosylation prevents TbetaRII proteins from being transported to the cell surface.	Nitrogen	30-31	transforming growth factor beta receptor 2	Homo sapiens	62-70
10570024-3	1999	The apparent K(m) values of human liver microsomes for S-mephobarbital N-demethylation were close to that of cDNA-expressed CYP2B6 (about 250 microM).	Nitrogen	71-72	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	124-130
22571197-8	2012	Collectively, these findings demonstrate that N-linked glycosylation is essentially required for the successful cell surface transportation of TbetaRII, suggesting a novel mechanism by which the TGF-beta sensitivity can be regulated by N-linked glycosylation levels of TbetaRII.	Nitrogen	46-47	transforming growth factor beta receptor 2	Homo sapiens	143-151
10570024-6	1999	Therefore, it appears that CYP2B6 mainly catalyzes S-mephobarbital N-demethylation in human liver microsomes.	Nitrogen	67-68	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	27-33
10809695-0	2000	In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex.	Nitrogen	107-115	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	148-152
10809695-0	2000	In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex.	Nitrogen	107-115	transcriptional regulator SIN3	Saccharomyces cerevisiae S288C	162-166
22571197-8	2012	Collectively, these findings demonstrate that N-linked glycosylation is essentially required for the successful cell surface transportation of TbetaRII, suggesting a novel mechanism by which the TGF-beta sensitivity can be regulated by N-linked glycosylation levels of TbetaRII.	Nitrogen	46-47	transforming growth factor beta receptor 2	Homo sapiens	269-277
22571197-8	2012	Collectively, these findings demonstrate that N-linked glycosylation is essentially required for the successful cell surface transportation of TbetaRII, suggesting a novel mechanism by which the TGF-beta sensitivity can be regulated by N-linked glycosylation levels of TbetaRII.	Nitrogen	236-237	transforming growth factor beta receptor 2	Homo sapiens	143-151
10809695-7	2000	Upon nitrogen depletion, repression at URS1 is released and Ume6 interacts with ArgRI and ArgRII, two proteins involved in arginine-dependent activation of CAR1 and CAR2, leading to high levels of the two catabolic enzymes despite a low cytosolic arginine pool.	Nitrogen	5-13	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	60-64
22688517-0	2012	Site-specific N-glycosylation identification of recombinant human lectin-like oxidized low density lipoprotein receptor-1 (LOX-1).	Nitrogen	14-15	oxidized low density lipoprotein receptor 1	Homo sapiens	123-128
10830723-0	2000	Coexpression of rat glutathione S-transferase A3 and human cytidine deaminase by a bicistronic retroviral vector confers in vitro resistance to nitrogen mustards and cytosine arabinoside in murine fibroblasts.	Nitrogen	144-152	cytidine deaminase	Homo sapiens	59-77
10625440-13	1999	In most K2 structures, the N atom of AMCHA places itself approximately 3.9 and 4.4A from the anionic groups of Glu(57) and Asp(55), respectively, while its carboxylate group, H-bonded to the Tyr(36) side chain OH(eta), ion-pairs the Arg(71) guanidinium group.	Nitrogen	27-28	endothelin receptor type A	Homo sapiens	213-216
22688517-2	2012	The N-glycosylation of LOX-1 has been shown to affect its biological functions in vivo and modulate the pathogenesis of atherosclerosis.	Nitrogen	4-5	oxidized low density lipoprotein receptor 1	Homo sapiens	23-28
10555955-4	1999	At liquid nitrogen temperature (-196 degrees C), we detected two kinds of photoproducts, bathopinopsin and isopinopsin, having their absorption maxima (lambda(max)) at 527 and approximately 440 nm, respectively, and we observed complete photoreversibility among pinopsin, bathopinopsin, and isopinopsin.	Nitrogen	10-18	opsin, pineal	Gallus gallus	94-102
10771285-6	2000	The additive contribution (75.3%) of human CYP3A and CYP2C to diazepam N-demethylation was also observed in the presence of both anti-CYP3A4/5 and anti-CYP2C8/9/19 monoclonal antibodies.	Nitrogen	71-72	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	152-158
22688517-3	2012	However, the N-glycosylation pattern of LOX-1 has not been described yet.	Nitrogen	13-14	oxidized low density lipoprotein receptor 1	Homo sapiens	40-45
22688517-4	2012	The present study was aimed at elucidating the N-glycosylation of recombinant human LOX-1 with regard to N-glycan profile and N-glycosylation sites.	Nitrogen	47-48	oxidized low density lipoprotein receptor 1	Homo sapiens	84-89
22688517-4	2012	The present study was aimed at elucidating the N-glycosylation of recombinant human LOX-1 with regard to N-glycan profile and N-glycosylation sites.	Nitrogen	105-106	oxidized low density lipoprotein receptor 1	Homo sapiens	84-89
22688517-5	2012	Here, an approach using nonspecific protease (Pronase E) digestion followed by MALDI-QIT-TOF MS and multistage MS (MS(3)) analysis is explored to obtain site-specific N-glycosylation information of recombinant human LOX-1, in combination with glycan structure confirmation through characterizing released glycans using tandem MS.	Nitrogen	167-168	oxidized low density lipoprotein receptor 1	Homo sapiens	216-221
10819158-6	2000	Structure activity relationships of this series of compounds revealed that a hydrophobic cholesteryl side chain, 3beta-hydroxy group and a C-6 nitrogen containing a hydrogen atom at position-6 are crucial for activity.	Nitrogen	143-151	complement C6	Homo sapiens	139-142
10537137-2	1999	The encoded protein, designated PRL-like protein J (PLP-J), is predicted to be synthesized as a precursor of 211 amino acids, modified by N-linked glycosylation, and secreted as a mature glycoprotein of 182 residues.	Nitrogen	138-139	prolactin family 3, subfamily c, member 1	Mus musculus	32-50
22836271-7	2012	Moreover, the IGF-1-mediated mitogenic microglia response was reduced by N-glycosylation inhibitor tunicamycine while coimmunoprecipitation experiments revealed galectin-3 binding to IGF-receptor 1 (R1), thus suggesting that interaction of galectin-3 with the N-linked glycans of receptors for growth factors is involved in IGF-R1 signaling.	Nitrogen	73-74	insulin-like growth factor 1	Mus musculus	14-19
10537137-2	1999	The encoded protein, designated PRL-like protein J (PLP-J), is predicted to be synthesized as a precursor of 211 amino acids, modified by N-linked glycosylation, and secreted as a mature glycoprotein of 182 residues.	Nitrogen	138-139	prolactin family 3, subfamily c, member 1	Mus musculus	52-57
10530928-9	1999	Thus, both enantiomers of 1 bound to the dopamine D2 receptor model in a similar fashion: a reinforced electrostatic interaction was present between the protonated nitrogen atoms and Asp114 in TM3; their carbonyl groups accepted a H-bond from Ser121 in TM3; their amide NH groups acted as H-bond donor to Tyr416 in TM7; and their benzamide phenyl rings were involved in a hydrophobic edge-to-face interaction with Trp386 in TM6.	Nitrogen	164-172	dopamine receptor D2	Homo sapiens	41-61
10705372-2	2000	Transcription of IME1 is detected under conditions of starvation for nitrogen and glucose, and in the presence of the MATa1 and MATalpha2 gene products.	Nitrogen	69-77	transcription factor IME1	Saccharomyces cerevisiae S288C	17-21
10650065-0	2000	Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids	Nitrogen	81-89	retinoic acid receptor gamma	Homo sapiens	49-57
22814602-6	2012	This Hbs function appears conserved, as mammalian Nephrin also promotes N signaling in mammalian cells.	Nitrogen	50-51	hibris	Drosophila melanogaster	5-8
10585855-1	1999	The red-cell anion exchanger (band 3; AE1) is a multispanning membrane protein that traverses the bilayer up to 14 times and is N-glycosylated at Asn-642.	Nitrogen	128-129	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	38-41
10441371-0	1999	Distinct but dispensable N-glycosylation of human CD69 proteins.	Nitrogen	25-26	CD69 molecule	Homo sapiens	50-54
10441371-2	1999	Here we examined the importance of N-glycosylation for the assembly and intracellular transport of CD69 proteins using mutant CD69 molecules that specifically lack typical and atypical N-glycan attachment motifs.	Nitrogen	35-36	CD69 molecule	Homo sapiens	99-103
22545627-0	2012	Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models.	Nitrogen	30-31	solute carrier family 2 member 4	Homo sapiens	24-29
10438547-6	1999	To study the formation of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex containing VAMP2 in parotid acinar cells, we prepared rabbit polyclonal antibody against the peptide corresponding to Arg(47)-Asp(64) of VAMP2 (anti-SER4256).	Nitrogen	38-39	vesicle-associated membrane protein 2	Rattus norvegicus	127-132
10654085-6	1999	On a non-repressive nitrogen source, AGP1 is induced, while GLN1, BAP2 and BAP3 are not.	Nitrogen	20-28	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	37-41
22545627-4	2012	Previously, aberrant GLUT4 N-glycosylation has been linked to increased basal cell-surface levels, while N-glycosylation-deficient GLUT4 was found to be quickly degraded.	Nitrogen	27-28	solute carrier family 2 member 4	Homo sapiens	21-26
22545627-5	2012	As recycling and degradation of GLUT4 are positively correlated, we hypothesized that incorrect N-glycosylation of GLUT4 might reduce its intracellular retention, resulting in an increased cell-surface recycling, in increased basal cell-surface levels, and in enhanced GLUT4 degradation.	Nitrogen	96-97	solute carrier family 2 member 4	Homo sapiens	32-37
10561453-2	1999	Mutant strain 1116 defective in N -glycosylation secretes MPP with truncated oligo-saccharide chains.	Nitrogen	32-33	M-phase phosphoprotein 6	Homo sapiens	58-61
22545627-5	2012	As recycling and degradation of GLUT4 are positively correlated, we hypothesized that incorrect N-glycosylation of GLUT4 might reduce its intracellular retention, resulting in an increased cell-surface recycling, in increased basal cell-surface levels, and in enhanced GLUT4 degradation.	Nitrogen	96-97	solute carrier family 2 member 4	Homo sapiens	115-120
10428866-3	1999	To examine the importance of N-linked glycosylation on insulin receptor processing, we have used glucose deprivation as a tool to alter protein glycosylation.	Nitrogen	29-30	insulin receptor	Mus musculus	55-71
22545627-5	2012	As recycling and degradation of GLUT4 are positively correlated, we hypothesized that incorrect N-glycosylation of GLUT4 might reduce its intracellular retention, resulting in an increased cell-surface recycling, in increased basal cell-surface levels, and in enhanced GLUT4 degradation.	Nitrogen	96-97	solute carrier family 2 member 4	Homo sapiens	115-120
22545627-9	2012	Our findings indicate that N-glycosylation is important for efficient trafficking of GLUT4 to its proper compartments, but once the transporter has arrived there, N-glycosylation plays no further major role in its intracellular trafficking, nor in its functional activity.	Nitrogen	27-28	solute carrier family 2 member 4	Homo sapiens	85-90
10534317-11	1999	The overall extent of IFA N-dechloroethylation varied with the CYP3A4 and CYP2B6 content of each liver, but was significantly lower for R-IFA (32 +/- 13%) than for S-IFA (62 +/- 17%, n = 8; p &lt;.001) in all livers examined.	Nitrogen	26-27	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	74-80
22621930-7	2012	An analysis of homology models docked with UDP-sugar donors indicates that Asn-391 in UGT3A1 is able to accommodate the N-acetyl group on C2 of UDP-GlcNAc so that the anomeric carbon atom (C1) is optimally situated for catalysis involving His-35.	Nitrogen	120-121	UDP glycosyltransferase family 3 member A1	Homo sapiens	86-92
10541284-0	1999	NS-398 upregulates constitutive cyclooxygenase-2 expression in the M-1 cortical collecting duct cell line.	Nitrogen	0-2	prostaglandin-endoperoxide synthase 2	Mus musculus	32-48
10425179-0	1999	CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated.	Nitrogen	48-49	platelet and endothelial cell adhesion molecule 1	Homo sapiens	0-4
10425179-0	1999	CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated.	Nitrogen	48-49	platelet and endothelial cell adhesion molecule 1	Homo sapiens	6-13
22706689-4	2012	Thermolytic characterization by DSC and TGA reveals an exothermic reaction corresponding to the loss of two dinitrogen molecules from compounds 5, 10, and 11.	Nitrogen	108-118	desmocollin 3	Homo sapiens	32-35
10559172-1	1999	Dal82p binds to the UIS(ALL) sites of allophanate-induced genes of the allantoin-degradative pathway and functions synergistically with the GATA family Gln3p and Gat1p transcriptional activators that are responsible for nitrogen catabolite repression-sensitive gene expression.	Nitrogen	220-228	Gat1p	Saccharomyces cerevisiae S288C	162-167
22706689-4	2012	Thermolytic characterization by DSC and TGA reveals an exothermic reaction corresponding to the loss of two dinitrogen molecules from compounds 5, 10, and 11.	Nitrogen	108-118	T-box transcription factor 1	Homo sapiens	40-43
22402276-3	2012	The predicted trout LAMP3 shares the characteristic features of LAMP family members such as a C-terminal lysosomal sorting motif (G-Y-D-R-I) in the short C-terminal cytoplasmic tail, typical for lysosomal targeting, four potential N-linked glycosylation sites (NXS/T), four conserved cysteines in the membrane-proximal domain and the luminal domain divided by a serine/proline-rich region.	Nitrogen	231-232	lysosomal associated membrane protein 3	Gallus gallus	20-25
10510156-10	1999	Conclusion CYP2C8 is primarily responsible for the hydroxylation and N-demethylation of rosiglitazone in human liver; with minor contributions from CYP2C9.	Nitrogen	69-70	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	11-17
22561161-1	2012	Doppel (Dpl) protein is a paralog of the prion protein (PrP) that shares 25% sequence similarity with the C-terminus of PrP, a common N-glycosylation site and a C-terminal signal peptide for attachment of a glycosylphophatidyl inositol anchor.	Nitrogen	134-135	prion protein	Mus musculus	56-59
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	49-55
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	180-186
10441426-3	1999	The decrease of BET surface area of montmorillonite induced by the larger size of exchange cation was interpreted with both the coverture of some surface roughness (surface screening effect) and the inhibition of nitrogen molecule into some pores (pore blocking effect).	Nitrogen	213-221	delta/notch like EGF repeat containing	Homo sapiens	16-19
11379854-12	1999	A transperitoneal protein- and amino acid-related nitrogen loss of 0.49 +/- 0.18 g and 0.48 +/- 0.12 g per dwell was measured using Glu/Bic and Glu/Lac, while a positive balance of 1.80 +/- 0.43 g was achieved with Amino/Bic.	Nitrogen	50-58	MIR155 host gene	Homo sapiens	136-139
11379854-12	1999	A transperitoneal protein- and amino acid-related nitrogen loss of 0.49 +/- 0.18 g and 0.48 +/- 0.12 g per dwell was measured using Glu/Bic and Glu/Lac, while a positive balance of 1.80 +/- 0.43 g was achieved with Amino/Bic.	Nitrogen	50-58	MIR155 host gene	Homo sapiens	221-224
22561161-1	2012	Doppel (Dpl) protein is a paralog of the prion protein (PrP) that shares 25% sequence similarity with the C-terminus of PrP, a common N-glycosylation site and a C-terminal signal peptide for attachment of a glycosylphophatidyl inositol anchor.	Nitrogen	134-135	prion protein	Mus musculus	120-123
22349139-11	2012	Assays with recombinant CYPs verified that the N-demethylation is catalysed by CYP3A4, CYP2C19 and CYP2B6.	Nitrogen	47-48	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	99-105
10409731-5	1999	Mutations in these genes cause the nitrogen-regulated general amino acid permease gene (GAP1) to be abnormally expressed and block the nonspecific induction of arginase (CAR1) and the peptide transporter (PTR2).	Nitrogen	35-43	Ptr2p	Saccharomyces cerevisiae S288C	205-209
22481162-0	2012	The Arabidopsis ubiquitin ligases ATL31 and ATL6 control the defense response as well as the carbon/nitrogen response.	Nitrogen	100-108	carbon/nitrogen insensitive 1	Arabidopsis thaliana	34-39
10425109-1	1999	A structure-based search and screen of our compound library identified N-(2-phenoxyethyl)-4-benzylpiperidine (8) as a novel N-methyl-D-aspartate (NMDA) receptor antagonist that has high selectivity for the NR1/2B subunit combination (IC(50) = 0.63 microM).	Nitrogen	71-72	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	206-212
22473518-5	2012	The Q band of Ni-DAP was redshifted and intensified compared with that of a nickel-porphyrin reference, due to the involvement of electronegative nitrogen atoms at the meso positions.	Nitrogen	146-154	death associated protein	Homo sapiens	17-20
10413093-1	1999	We have previously shown that an N-glycosylation site of N306 of HIV-1 gp120 is not necessary for the HIV-1 infectivity but protects HIV-1 from neutralising antibodies.	Nitrogen	33-34	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	71-76
22511698-2	2012	Methadone is primarily metabolized by N-demethylation to an inactive metabolite 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidene (EDDP) by CYP3A4 and CYP2B6.	Nitrogen	38-39	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	151-157
10411681-5	1999	RESULTS: Control opn +/+ mice showed a significant retention of blood urea nitrogen and creatinine, which is indicative of the development of ischemic acute renal dysfunction.	Nitrogen	75-83	secreted phosphoprotein 1	Mus musculus	17-20
22738658-7	2012	We discovered that gcn5Delta mutant strain displays strongly increased aldehyde dehydrogenase Ald6p activity, caused by blocking of Ald6p degradation by autophagy under nitrogen limitation conditions, leading to acetic acid accumulation.	Nitrogen	169-177	aldehyde dehydrogenase (NADP(+)) ALD6	Saccharomyces cerevisiae S288C	94-99
10476061-2	1999	Under conditions of steady-state nitrogen (N) supply, transcript levels of the AtAMT1 gene and Vmax values for high-affinity 13NH4+ influx were inversely correlated with levels of N provision.	Nitrogen	33-41	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	79-85
10476061-3	1999	Following re-supply of NH4NO3 to N-starved plants, AtAMT1 mRNA levels and 13NH4+ influx declined rapidly but remained high when the conversion of NH4+ to glutamine (Gln) was blocked with methionine sulfoximine (MSX).	Nitrogen	23-24	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	51-57
22307295-3	2012	In Sinorhizobium meliloti bacteroids from alfalfa, NAD(+)-malic enzyme (DME) is required for N(2) fixation, and this activity is thought to be required for the anaplerotic synthesis of pyruvate.	Nitrogen	93-97	NADP-dependent malic enzyme	Sinorhizobium fredii NGR234	72-75
10443017-3	1999	In particular, it is highlighted that both the benzene-condensed ring and the quinoline nitrogen are crucial determinants for optimal binding affinity to the hNK-3 receptor.	Nitrogen	88-96	tachykinin receptor 3	Homo sapiens	158-172
10364201-4	1999	Calnexin showed a preferential interaction with N-glycosylated AE1 relative to nonglycosylated AE1 both in vitro and in vivo.	Nitrogen	48-49	calnexin	Homo sapiens	0-8
10364201-4	1999	Calnexin showed a preferential interaction with N-glycosylated AE1 relative to nonglycosylated AE1 both in vitro and in vivo.	Nitrogen	48-49	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	63-66
22280345-1	2012	Ladostigil [(N-propargyl-(3R) aminoindan-5yl)-ethyl methyl carbamate] is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine), intended for the treatment of dementia co-morbid with extrapyramidal disorders and depression (presently in a Phase IIb clinical study).	Nitrogen	12-15	monoamine oxidase A	Rattus norvegicus	137-169
10364201-6	1999	Calnexin had access to novel N-glycosylated sites created in other extracytosolic loops in AE1 by site-directed or insertional mutagenesis.	Nitrogen	29-30	calnexin	Homo sapiens	0-8
10364201-6	1999	Calnexin had access to novel N-glycosylated sites created in other extracytosolic loops in AE1 by site-directed or insertional mutagenesis.	Nitrogen	29-30	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	91-94
10364201-8	1999	An association of calnexin with truncated versions of N-glycosylated AE1 was detected after release of the nascent chains from ribosomes with puromycin.	Nitrogen	54-55	calnexin	Homo sapiens	18-26
10364201-8	1999	An association of calnexin with truncated versions of N-glycosylated AE1 was detected after release of the nascent chains from ribosomes with puromycin.	Nitrogen	54-55	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	69-72
22280345-1	2012	Ladostigil [(N-propargyl-(3R) aminoindan-5yl)-ethyl methyl carbamate] is a dual acetylcholine-butyrylcholineesterase and brain selective monoamine oxidase (MAO)-A and -B inhibitor in vivo (with little or no MAO inhibitory effect in the liver and small intestine), intended for the treatment of dementia co-morbid with extrapyramidal disorders and depression (presently in a Phase IIb clinical study).	Nitrogen	12-15	monoamine oxidase A	Rattus norvegicus	156-159
10477169-2	1999	A linear skeleton with a N-containing aromatic ring attached at C3 of the top A-ring, a central pyran B-ring and a six-membered bottom C-ring with no alkylation at C7 are required for the antitumor activities of the lead compounds, a 3-pyridyl benzopyran (code name H10) and its somewhat weaker 2-pyridyl regioisomer (code name H19).	Nitrogen	25-26	H19, imprinted maternally expressed transcript	Mus musculus	328-331
10330124-3	1999	In this study, we have determined that the human DSPG3 gene is composed of seven exons: Exon 2 of DSPG3 includes the start codon, exons 4-7 code for the leucine-rich repeats, exons 3 and 7 contain the potential glycosaminoglycan attachment sites, and exon 7 contains the potential N-glycosylation sites and the stop codon.	Nitrogen	281-282	epiphycan	Homo sapiens	49-54
22184458-10	2012	A kinetic study showed that N(+)-glucuronidation of racemic morinidazole in both HLMs and in UGT1A9 obeyed a typical Michaelis-Menten plot.	Nitrogen	28-32	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	93-99
10085223-6	1999	The role of N-linked glycosylation in the interaction of NBMPR with hENT1 was examined by the quantification of binding of [3H]NBMPR to yeast producing either wild-type hENT1 or a glycosylation-defective mutant (hENT1/N48Q) in which Asn-48 was converted into Gln.	Nitrogen	12-13	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	68-73
10085223-6	1999	The role of N-linked glycosylation in the interaction of NBMPR with hENT1 was examined by the quantification of binding of [3H]NBMPR to yeast producing either wild-type hENT1 or a glycosylation-defective mutant (hENT1/N48Q) in which Asn-48 was converted into Gln.	Nitrogen	12-13	solute carrier family 29 member 1 (Augustine blood group)	Homo sapiens	68-72
10050042-3	1999	The GlcNAc residue linked to the Manalpha1-3 branch of BA-2 is lacking in BA-1 and the removal of this GlcNAc residue is not part of the usual biosynthetic pathway for N-linked sugar chains, suggesting the existence of an N-acetyl-beta-D-hexosaminidase.	Nitrogen	7-8	bone area 2	Mus musculus	55-59
21567396-2	2012	We previously showed that Nef disturbed the N-glycosylation/trafficking of Fms, a cytokine receptor essential for maintaining macrophages in an anti-inflammatory state, in an Hck-dependent manner.	Nitrogen	26-27	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	175-178
10364785-10	1999	The use of GLN diet and GH improved nitrogen balance and bowel growth on SBR groups, as compared to controls, but not cell proliferation.	Nitrogen	36-44	gonadotropin releasing hormone receptor	Rattus norvegicus	24-26
10091584-2	1999	In pig, neutral complex-type N-linked chains obtained from a ZPB/ZPC mixture possess sperm-binding activity.	Nitrogen	29-30	zona pellucida sperm-binding protein 3	Sus scrofa	65-68
10091584-8	1999	N-glycanase digestion indicated that ZPC has three N-glycosylation sites.	Nitrogen	0-1	zona pellucida sperm-binding protein 3	Sus scrofa	37-40
10433951-0	1999	Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro.	Nitrogen	31-39	interleukin 5	Homo sapiens	67-71
21567396-8	2012	These results suggest that Nef perturbs the structure and signaling of the Golgi by activating Hck at the Golgi, and thereby, induces the N-glycosylation/trafficking defect of Fms, which is in line with the idea that Src family kinases are crucial Golgi regulators.	Nitrogen	27-28	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	95-98
20654547-1	1999	In this study, we report in vitro methods using fluorescent probes to assess thiol depletion and the oxidative stress induced by mechlorethamine (HN2), a nitrogen mustard, on a human bronchial epithelial cell line (16HBE14o-).	Nitrogen	154-162	MT-RNR2 like 2 (pseudogene)	Homo sapiens	146-149
10091584-9	1999	Three glycopeptides each containing one of the N-glycosylation sites were obtained by tryptic digestion of ZPC and the N-glycosylation sites were revealed as Asn124, Asn146 and Asn271.	Nitrogen	47-48	zona pellucida sperm-binding protein 3	Sus scrofa	107-110
22385173-4	2012	Results indicate that properties, such as the distance between the bisquarternary nitrogen atoms, surface area, molecular volume, and hydrophilicity have important roles in the reactivation of OP-inhibited AChE.	Nitrogen	82-90	acetylcholinesterase	Mus musculus	206-210
9882513-0	1999	Regulatory role of mevalonate and N-linked glycosylation in proliferation and expression of the EWS/FLI-1 fusion protein in Ewing"s sarcoma cells.	Nitrogen	34-35	EWS RNA binding protein 1	Homo sapiens	96-99
10234440-1	1999	The interaction of potential pesticides, O,O-dialkyl S-ethoxycarbonylbromomethylthiophosphates (RO)2P(O)SCH(Br)COOC2H5 (R = Et, i-Pr, n-Pr, n-Bu, n-Am, or n-Hx) with the esterases of warm-blooded animals [acetylcholinesterase (ACE), butyryl cholinesterase (BCE), and carboxyl esterase (CE)] was studied.	Nitrogen	5-6	acetylcholinesterase	Mus musculus	205-225
10234440-1	1999	The interaction of potential pesticides, O,O-dialkyl S-ethoxycarbonylbromomethylthiophosphates (RO)2P(O)SCH(Br)COOC2H5 (R = Et, i-Pr, n-Pr, n-Bu, n-Am, or n-Hx) with the esterases of warm-blooded animals [acetylcholinesterase (ACE), butyryl cholinesterase (BCE), and carboxyl esterase (CE)] was studied.	Nitrogen	5-6	acetylcholinesterase	Mus musculus	227-230
10411908-11	1999	Our genetic analyses suggest the possibility that Cdc42p and Hsl7p compete for binding to Ste20p for pseudohyphal development when starved for nitrogen.	Nitrogen	143-151	protein arginine N-methyltransferase	Saccharomyces cerevisiae S288C	61-66
22118226-9	2012	MeIgQx also underwent N-oxidation by human P450s 1A1 and 1B1 at appreciable rates, whereas MeIQx was poorly metabolized by these P450s.	Nitrogen	22-23	cytochrome P450 family 1 subfamily B member 1	Homo sapiens	43-60
10450950-1	1999	A 2-pyrrolidinone ring containing a single hydroxymethyl side chain effectively replaces the N-acetylamino group of 4-(N-acetylamino)-3-guanidinobenzoic acid, a low micromolar inhibitor of influenza neuraminidase.	Nitrogen	93-94	neuraminidase 1	Homo sapiens	199-212
10625067-4	1999	Using this antibody, we show that SV2C is an N-glycosylated protein that is concentrated on small synaptic vesicles; in addition, it is found on microvesicles in adrenal chromaffin cells.	Nitrogen	45-46	synaptic vesicle glycoprotein 2c	Rattus norvegicus	34-38
22227571-5	2012	2DG blocks N-linked glycosylation of MICA/B by a reversible mechanism that can be alleviated by addition of d-mannose; this does not, however, affect the inhibition of glycolysis.	Nitrogen	11-12	MHC class I polypeptide-related sequence A	Homo sapiens	37-41
10233143-4	1999	The maximal activity of citrate synthase, selected as a measure of mitochondrial potential, showed greater increases (P &lt; 0.05) with H (1.22 +/- 0.10 mmol x h-1 x g wet wt-1; 70%; P &lt; 0.05) than with N (0.99 +/- 0.10 mmol x h-1 x g wet wt-1; 51%; P &lt; 0.05) compared with pretraining (0.658 +/- 0.09 mmol x h-1 x g wet wt-1).	Nitrogen	206-207	citrate synthase	Homo sapiens	24-40
22227571-8	2012	Corroborating this, tunicamycin, a selective inhibitor of N-linked glycosylation, abolished MICA/B surface expression without compromising activation of MICA promoter activity.	Nitrogen	58-59	MHC class I polypeptide-related sequence A	Homo sapiens	92-96
9837991-1	1998	The levels of N-alkyl purine and DNA interstrand crosslink formation, produced by the clinically used nitrogen mustard antitumour drug mechlorethamine (HN2), were quantitated at the level of specific genes in a panel of human tumour cell lines using modified Southern blotting methods.	Nitrogen	102-110	MT-RNR2 like 2 (pseudogene)	Homo sapiens	152-155
22227571-10	2012	Our data suggest that posttranslational N-linked glycosylation is strictly required for NKG2D ligand surface expression.	Nitrogen	40-41	killer cell lectin like receptor K1	Homo sapiens	88-93
22262650-2	2012	In the case of SREBP-2, these effects were correlated with the altered N-linked glycosylation of subtilisin/kexin-like isozyme-1 (SKI-1), the protease responsible for SREBP-2 processing under sterol-limiting conditions.	Nitrogen	71-72	sterol regulatory element-binding protein 2	Cricetulus griseus	15-22
9829637-5	1998	The combination of Con A-NS treatment followed by filtration with a microporous membrane efficiently removed virion-free gp120 as well as infectious viral particles from HIV-1 suspension.	Nitrogen	25-27	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	121-126
9792925-2	1998	LIF is a glycoprotein containing six putative N-glycosylation sites.	Nitrogen	46-47	leukemia inhibitory factor	Cricetulus griseus	0-3
10330477-6	1999	Transcript levels of AtAMT1;1, which possesses an affinity in the nanomolar range, steeply increased with ammonium uptake in roots when nitrogen nutrition became limiting, whereas those of AtAMT1;3 increased slightly, with AtAMT1;2 being more constitutively expressed.	Nitrogen	136-144	ammonium transporter 1;1	Arabidopsis thaliana	21-29
10330477-6	1999	Transcript levels of AtAMT1;1, which possesses an affinity in the nanomolar range, steeply increased with ammonium uptake in roots when nitrogen nutrition became limiting, whereas those of AtAMT1;3 increased slightly, with AtAMT1;2 being more constitutively expressed.	Nitrogen	136-144	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	21-27
10330477-7	1999	All three ammonium transporters showed diurnal variation in expression, but AtAMT1;3 transcript levels peaked with ammonium uptake at the end of the light period, suggesting that AtAMT1;3 provides a link between nitrogen assimilation and carbon provision in roots.	Nitrogen	212-220	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	76-82
10330477-7	1999	All three ammonium transporters showed diurnal variation in expression, but AtAMT1;3 transcript levels peaked with ammonium uptake at the end of the light period, suggesting that AtAMT1;3 provides a link between nitrogen assimilation and carbon provision in roots.	Nitrogen	212-220	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	179-185
10191257-0	1999	Transmembrane folding of the human erythrocyte anion exchanger (AE1, Band 3) determined by scanning and insertional N-glycosylation mutagenesis.	Nitrogen	116-117	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	64-75
10191257-1	1999	The human erythrocyte anion exchanger (AE1, Band 3) contains up to 14 transmembrane segments, with a single site of N-glycosylation at Asn642 in extracellular (EC) loop 4.	Nitrogen	116-117	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	39-50
10191257-2	1999	Scanning and insertional N-glycosylation mutagenesis were used to determine the folding pattern of AE1 in the membrane.	Nitrogen	25-26	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	99-102
22262650-2	2012	In the case of SREBP-2, these effects were correlated with the altered N-linked glycosylation of subtilisin/kexin-like isozyme-1 (SKI-1), the protease responsible for SREBP-2 processing under sterol-limiting conditions.	Nitrogen	71-72	sterol regulatory element-binding protein 2	Cricetulus griseus	167-174
10101147-10	1999	The antibody also was found to immunoinhibit CYP2B6-catalyzed N-demethylation of (S)-mephenytoin in human liver microsomes by 68 to 79%.	Nitrogen	62-63	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	45-51
9808729-7	1998	The metabolism of (+)-ABA was progressively inhibited at O2 concentrations less than 10% (v/v) and was very low (less than 5% of control) under N2. (+)-ABA 8"-hydroxylase activity was inhibited by tetcyclacis (50% inhibition at 10(-6) M), cytochrome c (oxidized form), and CO.	Nitrogen	145-147	cytochrome c	Zea mays	240-252
22359337-11	2012	Following CYP enzyme kinetic studies, CYP2B6 was the most relevant enzyme for both the N-demethylation of 3-BMC and 3-FMC after in vitro-in vivo extrapolation.	Nitrogen	87-88	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	10-13
9774483-7	1998	We then, using various N-glycosylation site mutants of NCAM, discovered that PST strongly prefer the sixth N-glycosylation site, which is the closest to the transmembrane domain, over the fifth site.	Nitrogen	23-24	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	77-80
9774483-7	1998	We then, using various N-glycosylation site mutants of NCAM, discovered that PST strongly prefer the sixth N-glycosylation site, which is the closest to the transmembrane domain, over the fifth site.	Nitrogen	55-56	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	77-80
10101149-0	1999	Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes.	Nitrogen	42-43	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	8-14
10072289-2	1999	The acid and base values were determined by Boehm"s method and the surface structures were studied by the BET method with N2 adsorption and iodine adsorption capacity.	Nitrogen	122-124	delta/notch like EGF repeat containing	Homo sapiens	106-109
22177407-1	2012	Structure-activity relationship studies of the pyrazolo[1,5-a]pyridine class of PI3 kinase inhibitors show that substitution off the hydrazone nitrogen and replacement of the sulfonyl both gave a loss of p110alpha selectivity, with the exception of an N-hydroxyethyl analogue.	Nitrogen	143-151	peptidase inhibitor 3	Homo sapiens	80-83
10090758-1	1999	Recently, we used 35 GHz pulsed 15N ENDOR spectroscopy to determine the position of the reactive guanidino nitrogen of substrate L-arginine relative to the high-spin ferriheme iron of holo-neuronal nitric oxide synthase (nNOS) [Tierney, D. L., et al.	Nitrogen	107-115	nitric oxide synthase 1	Homo sapiens	221-225
9778310-1	1998	By using a combination of biochemical methods (i.e., endoglycosidase H digestion and immunoblot and plant lectin binding studies), it was verified that pig flavin-containing monooxygenase (FMO1) was N-glycosylated.	Nitrogen	199-200	flavin containing dimethylaniline monoxygenase 1	Sus scrofa	189-193
9778310-4	1998	The results showed that pig FMO1 amino acid Asn120 was selectively N-glycosylated.	Nitrogen	67-68	flavin containing dimethylaniline monoxygenase 1	Sus scrofa	28-32
9778310-10	1998	Further analysis of pig FMO1 proteolytic peptides by LC/ESI/MS showed that the only residue that was N-glycosylated in pig FMO1 was Asn120.	Nitrogen	101-102	flavin containing dimethylaniline monoxygenase 1	Sus scrofa	24-28
9778310-10	1998	Further analysis of pig FMO1 proteolytic peptides by LC/ESI/MS showed that the only residue that was N-glycosylated in pig FMO1 was Asn120.	Nitrogen	101-102	flavin containing dimethylaniline monoxygenase 1	Sus scrofa	123-127
21953915-10	2012	Among the human UGT isoforms, only UGT1A9 had activity for the N-glucuronidation of TCC.	Nitrogen	63-64	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	16-19
9761621-6	1998	For nitrogen t-curves, a matching BET C constant ensured similarity only in the monolayer region, above which divergence progressively increased, becoming important close to saturation.	Nitrogen	4-12	delta/notch like EGF repeat containing	Homo sapiens	34-37
10227483-2	1999	The chicken IL-15 cDNA contains an open reading frame of 143 amino acids with a single potential N-linked glycosylation site.	Nitrogen	20-21	interleukin 15	Gallus gallus	12-17
21953915-10	2012	Among the human UGT isoforms, only UGT1A9 had activity for the N-glucuronidation of TCC.	Nitrogen	63-64	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	35-41
9761621-9	1998	As a consequence, the cumulated surface area obtained from the BJH model gave increasingly higher values than the BET nitrogen surface area.	Nitrogen	118-126	delta/notch like EGF repeat containing	Homo sapiens	114-117
21963446-3	2012	Mammalian GAA is synthesized as a precursor of ~110,000 Da that is N-glycosylated and targeted to the lysosome via the M6P receptors.	Nitrogen	67-68	alpha glucosidase	Homo sapiens	10-13
11543585-4	1998	15N-Nuclear magnetic resonance spectroscopic analyses revealed that the 15NH4+ liberated during the PAL reaction is first incorporated into the amide nitrogen of L-glutamine (L-Gln) and then into L-glutamate (L-Glu).	Nitrogen	150-158	LOW QUALITY PROTEIN: phenylalanine ammonia-lyase-like	Solanum tuberosum	100-103
9705316-0	1998	A 29-kilodalton Golgi soluble N-ethylmaleimide-sensitive factor attachment protein receptor (Vti1-rp2) implicated in protein trafficking in the secretory pathway.	Nitrogen	30-31	v-SNARE protein VTI1	Saccharomyces cerevisiae S288C	93-97
9931023-2	1999	At the epsilon position, an upfield shift of 4 ppm is observed while the eta nitrogens develop a pair of "wing" peaks separated by 24 ppm.	Nitrogen	77-86	endothelin receptor type A	Homo sapiens	73-76
10091323-2	1999	The RHK1/ALG3 gene encodes a mannosyl-transferase that is involved in the synthesis of an oligosaccharide in protein N-glycosylation.	Nitrogen	117-118	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	4-8
10091323-2	1999	The RHK1/ALG3 gene encodes a mannosyl-transferase that is involved in the synthesis of an oligosaccharide in protein N-glycosylation.	Nitrogen	117-118	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	9-13
10048020-1	1999	In Saccharomyces cerevisiae, the transcription factors Gln3p and Nil1p of the GATA family play a determinant role in expression of genes that are subject to nitrogen catabolite repression.	Nitrogen	157-165	Gat1p	Saccharomyces cerevisiae S288C	65-70
10048020-4	1999	Gan1p is required for full expression of GLN1, GDH2 and also other nitrogen utilization genes, including GAP1, PUT4, MEP2 and GDH1.	Nitrogen	67-75	proline permease PUT4	Saccharomyces cerevisiae S288C	111-115
10048020-10	1999	Ada1/Gan1p thus represents the first reported case of an accessory protein (a co-activator) linking the GATA-binding proteins Gln3p and Nil1p, mediating nitrogen-regulated transcription, to the basal transcription machinery.	Nitrogen	153-161	Gat1p	Saccharomyces cerevisiae S288C	136-141
10199594-4	1999	Among the hepatic P450s, the N-demethylation of aminopyrine was catalysed most efficiently by CYP2C19, followed by CYP2C8, 2D6, 2C18 and 1A2, whereas the activity with CYP2E1 was negligible.	Nitrogen	29-30	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	115-121
10199594-10	1999	Human steroidogenic CYP17 also catalysed aminopyrine N-demethylation and the activity was comparable with that for CYP3A4 which is a dominant P450 in human liver.	Nitrogen	53-54	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	20-25
9685242-2	1998	Since CA-4 has limited aqueous solubility, the target compounds were designed to improve solubility by introduction of a nitrogen-containing group.	Nitrogen	121-129	carbonic anhydrase 4	Mus musculus	6-10
23119112-12	2012	The expression of GAP-43, a sprouting related protein, was decreased in the DEVD and siRNA group as compared to NS group (P&lt;0.05).	Nitrogen	112-114	growth associated protein 43	Rattus norvegicus	18-24
9639683-5	1998	The predicted 411 amino acid sequence of human C6ST contains an N-terminal hydrophobic domain consistent with membrane insertion, four potential sites for N-linked glycosylation, several consensus sequences for protein phosphorylation, and one RGD sequence.	Nitrogen	64-65	carbohydrate sulfotransferase 3	Homo sapiens	47-51
9880538-10	1999	These results suggest apical sorting of enteropeptidase depends on N-linked glycosylation of the serine protease domain and an amino-terminal segment that includes an O-glycosylated mucin-like domain and three potential N-glycosylation sites.	Nitrogen	67-68	transmembrane serine protease 15	Canis lupus familiaris	40-55
9880538-10	1999	These results suggest apical sorting of enteropeptidase depends on N-linked glycosylation of the serine protease domain and an amino-terminal segment that includes an O-glycosylated mucin-like domain and three potential N-glycosylation sites.	Nitrogen	220-221	transmembrane serine protease 15	Canis lupus familiaris	40-55
9882513-5	1999	We investigated whether MVA synthesis and N-linked glycosylation could be involved in regulation of the expression of the EWS/FLI-1 fusion protein, which in fact contains four potential sites for N-linked glycosylation.	Nitrogen	42-43	EWS RNA binding protein 1	Homo sapiens	122-125
22480418-13	2012	They also show that uric acid, a multifunctional metabolite at the crossroads of nitrogen waste and of antioxidant defences, can be influenced by SSAO, in a manner apparently related to changes in glucose homeostasis.	Nitrogen	81-89	amine oxidase, copper containing 3	Mus musculus	146-150
9882513-5	1999	We investigated whether MVA synthesis and N-linked glycosylation could be involved in regulation of the expression of the EWS/FLI-1 fusion protein, which in fact contains four potential sites for N-linked glycosylation.	Nitrogen	196-197	EWS RNA binding protein 1	Homo sapiens	122-125
9882513-13	1999	Taken together, our data suggest that the regulatory role of N-linked glycosylation in the expression of the EWS/FLI-1 fusion protein is important for growth of Ewing"s sarcoma cells.	Nitrogen	61-62	EWS RNA binding protein 1	Homo sapiens	109-112
23144631-6	2012	We find that TSC2 is expressed highly in ISCs, where it maintains stem cell identity, and that N-mediated repression of TSC2 in EBs is required and sufficient to promote EC differentiation.	Nitrogen	95-96	gigas	Drosophila melanogaster	120-124
9858571-7	1999	The rer2 mutant shows several other characteristic phenotypes: slow growth, defects in N and O glycosylation, sensitivity to hygromycin B, and abnormal accumulation of membranes, including the ER and the Golgi membranes.	Nitrogen	87-88	ditrans,polycis-polyprenyl diphosphate synthase	Saccharomyces cerevisiae S288C	4-8
9832436-10	1998	PLP-H contains two putative N-glycosylation sites and eight cysteine residues, of which six are highly conserved in the placental PRL family.	Nitrogen	28-29	prolactin family 8, subfamily A, member 4	Rattus norvegicus	0-5
22438913-9	2012	We next found that both IGF1R and IR were N-linked glyosylated in figitumumab-sensitive cells.	Nitrogen	42-43	insulin receptor	Mus musculus	34-36
22039046-2	2011	TorC1 inhibitor, rapamycin (Rap), and glutamine synthetase inhibitor, methionine sulfoximine (Msx), elicit responses grossly similar to those of limiting nitrogen, implicating both glutamine synthesis and TorC1 in the regulation of Gln3 and Gat1.	Nitrogen	154-162	CREB regulated transcription coactivator 1	Homo sapiens	0-5
21994464-9	2011	By extensive study of receptor binding, neuraminidase activity, oligomerization, and fusion-promoting functions of the mutant proteins, we found a correlation between the position of the N-glycosylation mutants on the stalk structure and their neuraminidase activities as well as their abilities to promote fusion.	Nitrogen	187-188	neuraminidase 1	Homo sapiens	40-53
9794807-4	1998	Northern blot analysis showed the presence of the YNA1 transcript in cells incubated in nitrate, nitrate plus ammonium, ammonium, and nitrogen-free media, with a decrease in its levels in those cells incubated in ammonium.	Nitrogen	134-142	rRNA (cytosine-C5-)-methyltransferase NOP2	Saccharomyces cerevisiae S288C	50-54
9791119-1	1998	GATA family proteins Gln3p, Gat1p, Dal80p, and Deh1p mediate the regulation of nitrogen catabolite repression (NCR)-sensitive gene expression in Saccharomyces cerevisiae.	Nitrogen	79-87	Gat1p	Saccharomyces cerevisiae S288C	28-33
9791119-1	1998	GATA family proteins Gln3p, Gat1p, Dal80p, and Deh1p mediate the regulation of nitrogen catabolite repression (NCR)-sensitive gene expression in Saccharomyces cerevisiae.	Nitrogen	79-87	Gzf3p	Saccharomyces cerevisiae S288C	47-52
21994464-9	2011	By extensive study of receptor binding, neuraminidase activity, oligomerization, and fusion-promoting functions of the mutant proteins, we found a correlation between the position of the N-glycosylation mutants on the stalk structure and their neuraminidase activities as well as their abilities to promote fusion.	Nitrogen	187-188	neuraminidase 1	Homo sapiens	244-257
11286349-5	1998	MEASUREMENTS AND RESULTS: The chronotropic 25 dose (CD25), an in vivo measure of beta-adrenergic receptor sensitivity derived from the heart rate response to a graded infusion of isoproterenol, was determined while subjects breathed either a normoxic (21% O2, 79% N2) or a hypoxic (15% O2, 85% N2) gas mixture.	Nitrogen	264-266	interleukin 2 receptor subunit alpha	Homo sapiens	52-56
11286349-5	1998	MEASUREMENTS AND RESULTS: The chronotropic 25 dose (CD25), an in vivo measure of beta-adrenergic receptor sensitivity derived from the heart rate response to a graded infusion of isoproterenol, was determined while subjects breathed either a normoxic (21% O2, 79% N2) or a hypoxic (15% O2, 85% N2) gas mixture.	Nitrogen	294-296	interleukin 2 receptor subunit alpha	Homo sapiens	52-56
9789003-7	1998	In wild-type Chinese hamster ovary cells the N-linked carbohydrate chains of SCAP were mostly in the endoglycosidase H-sensitive form when cells were grown in medium containing 25-hydroxycholesterol.	Nitrogen	45-46	sterol regulatory element-binding protein cleavage-activating protein	Cricetulus griseus	77-81
24159466-5	2011	The amino acids lengths and number of potential N-linked glycosylation sites (PNGS) in HIV-1 env gene was positively correlated with neutralized antibody responses during the early stages of infection.	Nitrogen	48-49	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	93-96
9767079-0	1998	Effects of the loss of capacity for N-glycosylation on the transport activity and cellular localization of the human reduced folate carrier.	Nitrogen	36-37	solute carrier family 19 member 1	Homo sapiens	117-139
9767079-1	1998	The role of N-glycosylation in reduced folate carrier (RFC) transport and membrane targeting was examined in transport-deficient K562 (K500E) cells transfected with human RFC cDNAs.	Nitrogen	12-13	solute carrier family 19 member 1	Homo sapiens	31-53
22304108-2	2011	The usual McMillan mean-field approach predicts that the SmA-N transition in bulk samples can be continuous or discontinuous (first or second order) depending on the molecular geometry, with a tricritical point separating these two regimes.	Nitrogen	61-62	survival of motor neuron 1, telomeric	Homo sapiens	57-60
9767079-1	1998	The role of N-glycosylation in reduced folate carrier (RFC) transport and membrane targeting was examined in transport-deficient K562 (K500E) cells transfected with human RFC cDNAs.	Nitrogen	12-13	solute carrier family 19 member 1	Homo sapiens	55-58
9767079-7	1998	Collectively, our results demonstrate that N-glycosylation of human RFC plays no significant role in either transport function or membrane targeting.	Nitrogen	43-44	solute carrier family 19 member 1	Homo sapiens	68-71
9712041-7	1998	Granulysin- and ceramide-induced apoptosis are similar in that they both are only minimally inhibited by the more selective cysteine protease p32 (caspase 3)-like caspase inhibitor N-acetyl-Asp-Glu-Val-Asp aldehyde, while they are significantly inhibited by the more general caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone (Z-VAD-fmk).	Nitrogen	181-182	granulysin	Homo sapiens	0-10
22172828-10	2011	Moreover, the urinary PIBF level was significantly lower among patients who had increased creatinine and urea nitrogen levels in blood samples (P&lt;.05 and P&lt;.01, respectively).	Nitrogen	110-118	progesterone immunomodulatory binding factor 1	Homo sapiens	22-26
9712041-7	1998	Granulysin- and ceramide-induced apoptosis are similar in that they both are only minimally inhibited by the more selective cysteine protease p32 (caspase 3)-like caspase inhibitor N-acetyl-Asp-Glu-Val-Asp aldehyde, while they are significantly inhibited by the more general caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone (Z-VAD-fmk).	Nitrogen	181-182	inhibitor of growth family member 2	Homo sapiens	142-145
9757569-1	1998	A mutant angiotensinogen, S14N, in which Ser14 of ovine angiotensinogen was replaced by Asn to form a N-glycosylation site, was produced in CHO cells.	Nitrogen	29-30	angiotensinogen	Cricetulus griseus	9-24
9698292-9	1998	Therefore, the N-demethylation of (S)-MP to nirvanol may be a useful means of probing the activity of CYP2B6 in vitro when concentrations of &gt;1000 microM are used, but it is unlikely to be a suitable phenotyping tool for this isoform in vivo, where concentrations of &gt;1000 microM are rarely encountered.	Nitrogen	15-16	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	102-108
9694965-0	1998	Characterization of the role of N-linked glycosylation on the cell signaling and expression of the human thromboxane A2 receptor alpha and beta isoforms.	Nitrogen	32-33	thromboxane A2 receptor	Homo sapiens	105-128
9701597-12	1998	The results from this investigation demonstrate that GAD activity in leaves is altered by different nitrogen treatments, suggesting that GAD2 may play a unique role in nitrogen metabolism.	Nitrogen	100-108	glutamate decarboxylase 2	Arabidopsis thaliana	137-141
9701597-12	1998	The results from this investigation demonstrate that GAD activity in leaves is altered by different nitrogen treatments, suggesting that GAD2 may play a unique role in nitrogen metabolism.	Nitrogen	168-176	glutamate decarboxylase 2	Arabidopsis thaliana	137-141
9668061-0	1998	Dimerization of the human MUC2 mucin in the endoplasmic reticulum is followed by a N-glycosylation-dependent transfer of the mono- and dimers to the Golgi apparatus.	Nitrogen	83-84	LOC100508689	Homo sapiens	31-36
9668061-6	1998	The non-N-glycosylated species of the MUC2 mucin were retained in the endoplasmic reticulum because no O-glycosylated species were precipitated after inhibition by tunicamycin.	Nitrogen	8-9	LOC100508689	Homo sapiens	43-48
9667974-3	1998	Removal of a single methylene bridge between the amidine nitrogen and phenyl ring to give N-(3-(aminomethyl)phenyl)acetamidine (14) dramatically altered the selectivity to give a neuronal selective nitric oxide synthase (nNOS) inhibitor.	Nitrogen	57-65	nitric oxide synthase 1	Homo sapiens	179-219
9667974-3	1998	Removal of a single methylene bridge between the amidine nitrogen and phenyl ring to give N-(3-(aminomethyl)phenyl)acetamidine (14) dramatically altered the selectivity to give a neuronal selective nitric oxide synthase (nNOS) inhibitor.	Nitrogen	57-65	nitric oxide synthase 1	Homo sapiens	221-225
9642295-3	1998	Here, we use protease protection and N-linked glycosylation site-mapping techniques to define the topology of the eight membrane-spanning domains of SCAP.	Nitrogen	37-38	SREBF chaperone	Homo sapiens	149-153
9680203-4	1998	Competitive electrophoretic mobility shift analysis showed that H-NS bound specifically to a pap DNA fragment containing the GATC-I and GATC-II sites.	Nitrogen	66-68	putative antirestriction protein	Escherichia coli	93-96
9654121-1	1998	Though the cell surface-associated costimulator B7-1(CD80) is known to be highly N-glycosylated, the functional significance of this N-glycosylation has not been evaluated.	Nitrogen	81-82	CD80 molecule	Homo sapiens	48-52
9654121-1	1998	Though the cell surface-associated costimulator B7-1(CD80) is known to be highly N-glycosylated, the functional significance of this N-glycosylation has not been evaluated.	Nitrogen	81-82	CD80 molecule	Homo sapiens	53-57
9654121-1	1998	Though the cell surface-associated costimulator B7-1(CD80) is known to be highly N-glycosylated, the functional significance of this N-glycosylation has not been evaluated.	Nitrogen	133-134	CD80 molecule	Homo sapiens	48-52
9654121-1	1998	Though the cell surface-associated costimulator B7-1(CD80) is known to be highly N-glycosylated, the functional significance of this N-glycosylation has not been evaluated.	Nitrogen	133-134	CD80 molecule	Homo sapiens	53-57
9654121-2	1998	Two experimental approaches were taken to assess the influence of N-glycosylation on human B7-1 function.	Nitrogen	66-67	CD80 molecule	Homo sapiens	91-95
9654121-3	1998	First, stable K562 transfectants expressing human B7-1 were treated with the N-glycosylation inhibitor tunicamycin.	Nitrogen	77-78	CD80 molecule	Homo sapiens	50-54
9654121-9	1998	Taken together, these data indicate that the N-glycosylation of B7-1 is not required for its association with counter-receptors.	Nitrogen	45-46	CD80 molecule	Homo sapiens	64-68
9565551-3	1998	The absorption spectrum of each mutant enzyme undergoes a pH-dependent change (pKa approximately 7.7) from a form with a protonated internal aldimine nitrogen (lambdamax = 416 nm) to a deprotonated form (lambdamax = 336 nm), whereas the absorption spectra of the wild type tryptophan synthase beta2 subunit and alpha2 beta2 complex are pH-independent.	Nitrogen	150-158	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	293-298
9565551-3	1998	The absorption spectrum of each mutant enzyme undergoes a pH-dependent change (pKa approximately 7.7) from a form with a protonated internal aldimine nitrogen (lambdamax = 416 nm) to a deprotonated form (lambdamax = 336 nm), whereas the absorption spectra of the wild type tryptophan synthase beta2 subunit and alpha2 beta2 complex are pH-independent.	Nitrogen	150-158	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	318-323
9573211-2	1998	Using strains with disruptions in the genes for multiple permeases, we demonstrated that Ycc5 (which we have renamed Agp1) is involved in the transport of asparagine and glutamine, performed a kinetic analysis of this activity, and showed that AGP1 expression is subject to nitrogen repression.	Nitrogen	274-282	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	89-93
9573211-2	1998	Using strains with disruptions in the genes for multiple permeases, we demonstrated that Ycc5 (which we have renamed Agp1) is involved in the transport of asparagine and glutamine, performed a kinetic analysis of this activity, and showed that AGP1 expression is subject to nitrogen repression.	Nitrogen	274-282	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	117-121
9573211-2	1998	Using strains with disruptions in the genes for multiple permeases, we demonstrated that Ycc5 (which we have renamed Agp1) is involved in the transport of asparagine and glutamine, performed a kinetic analysis of this activity, and showed that AGP1 expression is subject to nitrogen repression.	Nitrogen	274-282	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	244-248
9587408-3	1998	The role of N-glycosylation of TXA2R in ligand binding was investigated in the insect cells over-expressed with recombinant TXA2R.	Nitrogen	12-13	thromboxane A2 receptor	Homo sapiens	31-36
9587408-4	1998	Deletion of the carbohydrate moiety by adding tunicamycin during infection of Sf21 cells or mutation of both potential N-glycosylation sites (Asn-4 and Asn-16) abolished the ligand binding of TXA2R, suggesting that N-glycosylation is crucial for binding function.	Nitrogen	119-120	thromboxane A2 receptor	Homo sapiens	192-197
9587408-4	1998	Deletion of the carbohydrate moiety by adding tunicamycin during infection of Sf21 cells or mutation of both potential N-glycosylation sites (Asn-4 and Asn-16) abolished the ligand binding of TXA2R, suggesting that N-glycosylation is crucial for binding function.	Nitrogen	215-216	thromboxane A2 receptor	Homo sapiens	192-197
9528770-3	1998	Upon nitrogen depletion a transient induction in the transcription of IME1 is observed in MATa/MATalpha diploids but not in MAT-insufficient strains.	Nitrogen	5-13	transcription factor IME1	Saccharomyces cerevisiae S288C	70-74
9514644-5	1998	At this latter detergent concentration, the activity of prenylated protein methyltransferase (PPMT) was strongly inhibited and that of l-isoaspartyl/d-aspartylmethyltransferase (PIMT) was increased twofold, as measured with their respective exogenous substrates, N-acetyl-S-farnesyl cysteine and ovalbumin.	Nitrogen	263-264	isoprenylcysteine carboxyl methyltransferase	Rattus norvegicus	56-92
9514644-5	1998	At this latter detergent concentration, the activity of prenylated protein methyltransferase (PPMT) was strongly inhibited and that of l-isoaspartyl/d-aspartylmethyltransferase (PIMT) was increased twofold, as measured with their respective exogenous substrates, N-acetyl-S-farnesyl cysteine and ovalbumin.	Nitrogen	263-264	isoprenylcysteine carboxyl methyltransferase	Rattus norvegicus	94-98
9669748-3	1998	Affinity chromatography of TFPI using immobilized heparin derivatives regiospecifically desulfated at O-6 of the glucosamine residue, N-2 of the glucosamine residue, and/or O-2 of the iduronic acid residue indicated that all the sulfate groups in heparin appeared to be required for TFPI-heparin interaction.	Nitrogen	134-135	tissue factor pathway inhibitor	Homo sapiens	27-31
9535093-7	1998	This mutant (NGR omega nodD2) was deficient in nitrogen fixation on Vigna unguiculata and induced pseudonodules on Tephrosia vogelii.	Nitrogen	47-55	transcriptional regulator NodD2	Sinorhizobium fredii NGR234	23-28
9492298-2	1998	ERp29 was induced to high levels in the rat hepatoma cells under metabolic stress conditions known to cause an aberrant accumulation of proteins in the ER [(e.g. culture in presence of the Ca2+ ionophore A23187, inhibitors of Ca2+-ATPase (thapsigargin), intracellular protein transport (brefeldin A), or protein N-glycosylation (tunicamycin)].	Nitrogen	312-313	endoplasmic reticulum protein 29	Rattus norvegicus	0-5
9871472-3	1998	An anoxic lesion was induced by exposing the cultures to 100% N2 for 150 min, resulting in a pronounced loss of pyramidal neurons, as identified using NMDA-R1 receptor subunit immunohistochemistry.	Nitrogen	62-64	glutamate ionotropic receptor NMDA type subunit 1	Rattus norvegicus	151-158
10353717-1	1998	Band 3, the human erythrocyte anion exchanger (AE1), and the glucose transporter (GLUT1) proteins each contain a single site of N-glycosylation that is heterogeneously glycosylated.	Nitrogen	128-129	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	47-50
9706384-4	1998	The nitrogen content of MUC1 mucin was determined to be intermediate between the mucin polypeptide and the carbohydrates.	Nitrogen	4-12	mucin 1, cell surface associated	Homo sapiens	24-28
9706384-4	1998	The nitrogen content of MUC1 mucin was determined to be intermediate between the mucin polypeptide and the carbohydrates.	Nitrogen	4-12	LOC100508689	Homo sapiens	29-34
9683732-17	1998	N-Myristylation of such conformationally constrained hexapeptides may, therefore, provide a means of producing cell-permeant inhibitors of the cardiac Na-Ca exchanger.	Nitrogen	0-1	sodium/calcium exchanger 1	Oryctolagus cuniculus	151-166
9635580-1	1998	TER286 is a latent drug activated by human glutathione S-transferase (GST) isoforms P1-1 and A1-1 to produce a nitrogen mustard alkylating agent.	Nitrogen	111-119	S100 calcium binding protein A10 (calpactin)	Mus musculus	84-88
9614085-5	1998	K+ starvation and nitrogen starvation hyperpolarize both TRK1 TRK2 and trk1Delta trk2Delta cells, thus suggesting that other proteins, in addition to Trk1p and Trk2p, participate in the control of the membrane potential.	Nitrogen	18-26	Trk1p	Saccharomyces cerevisiae S288C	57-61
9614085-5	1998	K+ starvation and nitrogen starvation hyperpolarize both TRK1 TRK2 and trk1Delta trk2Delta cells, thus suggesting that other proteins, in addition to Trk1p and Trk2p, participate in the control of the membrane potential.	Nitrogen	18-26	Trk1p	Saccharomyces cerevisiae S288C	71-75
9636668-1	1998	Acylpeptide hydrolase, which removes the N-acetylated amino acids from peptide substrates was purified from bovine lens, truncated in vitro to a 55 kDa enzyme by trypsin digestion and characterized.	Nitrogen	41-42	acylaminoacyl-peptide hydrolase	Bos taurus	0-21
9611168-0	1998	Arabidopsis mutants define an in vivo role for isoenzymes of aspartate aminotransferase in plant nitrogen assimilation.	Nitrogen	97-105	aspartate aminotransferase	Arabidopsis thaliana	61-87
9611168-7	1998	These results indicate that cytosolic AAT2 is the major isoenzyme controlling aspartate synthesized for nitrogen transport in the light, and that this aspartate pool is converted to asparagine when plants are dark adapted.	Nitrogen	104-112	aspartate aminotransferase 2	Arabidopsis thaliana	38-42
9751158-9	1998	Since N-acetylation regulates the biological activity of alphaMSH and beta-endorphin in an opposite manner, we propose a model where the rate of secretion dictated by the bioelectric activity of the presynaptic neuron modulates POMC-derived peptide maturation and the resulting biological signal sensed by the postsynaptic plate.	Nitrogen	6-7	pro-opiomelanocortin-alpha	Mus musculus	70-84
9568695-8	1998	The sulfate content of heparin/heparan sulfate was also important for the enhancement of amylin fibril formation in the order of heparin &gt; N-desulfated N-acetylated heparin &gt; completely desulfated N-sulfated heparin &gt; completely desulfated N-acetylated heparin.	Nitrogen	142-143	islet amyloid polypeptide	Homo sapiens	89-95
9549886-5	1998	The mutual positions of the aromatic ring, nitrogen atom and terminal amine are considered to form the pharmacophore of the 5-HT3 receptor agonist in the gut.	Nitrogen	43-51	5-hydroxytryptamine receptor 3A	Rattus norvegicus	124-138
9787911-4	1998	The strong N-H combination band found at 4867 cm-1 in the spectrum of native RNase A shifts to 4878 cm-1 upon thermal unfolding.	Nitrogen	11-12	ribonuclease A family member 1, pancreatic	Homo sapiens	77-84
10890753-1	1998	Currently, white lupin (Lupinus albus L.) is gaining importance due to its high nitrogen fixation capability and potential in sustainable crop production systems.	Nitrogen	80-88	5'-nucleotidase, cytosolic IIIA	Homo sapiens	17-22
21277238-3	2011	Monomeric, dimeric, and/or multimeric forms of cauxin carrying N-glycosylations were detected on Western blots of feline SF but most were monomeric.	Nitrogen	63-64	carboxylesterase 5A	Felis catus	47-53
9428654-1	1997	In the present study, we demonstrated that the attachment of the nonpolar isopropylic carbon chain in the nitrogen of oxamate, converted this competitive inhibitor of LDH isozymes into a powerful selective inhibitor of mouse LDH-C4.	Nitrogen	106-114	lactate dehydrogenase A	Mus musculus	167-170
9654739-5	1998	There were three potential N-glycosylation sites in the chitinase of B. mori at the amino acid residues 86-89, NFTS 304-307, NATG, 398-401, NYTV, whereas two potential N-glycosylation sites were present at the amino acid residues 86-89, NFTA and 304-307, NATG, in that of H. cunea.	Nitrogen	27-28	chitinase	Bombyx mori	56-65
9654739-5	1998	There were three potential N-glycosylation sites in the chitinase of B. mori at the amino acid residues 86-89, NFTS 304-307, NATG, 398-401, NYTV, whereas two potential N-glycosylation sites were present at the amino acid residues 86-89, NFTA and 304-307, NATG, in that of H. cunea.	Nitrogen	111-112	chitinase	Bombyx mori	56-65
22023129-7	2011	For all 3 species, inhibitors of CYP3A4, CYP2A6, CYP2C19, CYP2B6, and CYP2C9 diminished N-demethylation of ketamine.	Nitrogen	88-89	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	58-64
9466820-3	1998	A similar enzyme, CPSase III, catalyzes this reaction in fish; CPSase III differs from CPSase I in that it utilizes glutamine as the nitrogen-donating substrate instead of ammonia.	Nitrogen	133-141	carbamoyl-phosphate synthase 1	Homo sapiens	18-26
9468338-3	1998	An N-glycosylation consensus sequence Asn-X-Ser/Thr was created at positions 103, 183, 196, 284 and 457 in the variable regions being strongly hydrophilic revealed from the alignment of amino acid sequences of various glycinin-type proteins.	Nitrogen	3-4	LOC732636	Glycine max	218-226
9433921-0	1997	The role of N-terminal glycosylation in the human oxytocin receptor.	Nitrogen	12-13	oxytocin receptor	Homo sapiens	50-67
9294445-1	1997	Deletion of most of the coding region of the ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) resulted in loss of ppGpp synthesis, both upon entry into stationary phase under conditions of nitrogen limitation and following amino acid starvation during exponential growth, but had no effect on growth rate.	Nitrogen	202-210	RELA proto-oncogene, NF-kB subunit	Homo sapiens	68-72
21624033-0	2011	Introduction of the ZmDof1 gene into rice enhances carbon and nitrogen assimilation under low-nitrogen conditions.	Nitrogen	62-70	DNA-binding protein MNB1	Zea mays	20-26
9294445-2	1997	The relA mutant, which showed continued rRNA synthesis upon amino acid depletion (the relaxed response), failed to produce the antibiotics undecylprodigiosin (Red) and actinorhodin (Act) under conditions of nitrogen limitation.	Nitrogen	207-215	RELA proto-oncogene, NF-kB subunit	Homo sapiens	4-8
21624033-0	2011	Introduction of the ZmDof1 gene into rice enhances carbon and nitrogen assimilation under low-nitrogen conditions.	Nitrogen	94-102	DNA-binding protein MNB1	Zea mays	20-26
21624033-3	2011	Maize Dof1 (ZmDof1) is a plant-specific transcription factor shown to promote nitrogen assimilation in Arabidopsis thaliana (Arabidopsis) even under nitrogen-deficient conditions.	Nitrogen	78-86	DNA-binding protein MNB1	Zea mays	6-10
9928474-4	1998	Nod factors act as morphogens that, under conditions of nitrogen limitation, induce cells within the root cortex to divide and to develop into nodule primordia.	Nitrogen	56-64	atrophin 1	Homo sapiens	0-3
21624033-3	2011	Maize Dof1 (ZmDof1) is a plant-specific transcription factor shown to promote nitrogen assimilation in Arabidopsis thaliana (Arabidopsis) even under nitrogen-deficient conditions.	Nitrogen	78-86	DNA-binding protein MNB1	Zea mays	12-18
9281482-4	1997	It is found, however, that in cases of slow internal motions with characteristic times of more than 3-4 ns, the effective tauR provided by the T1/T2 ratio for individual amide nitrogens can be used for the characterization of the fast picosecond internal dynamics.	Nitrogen	176-185	interleukin 1 receptor like 1	Homo sapiens	143-148
21624033-3	2011	Maize Dof1 (ZmDof1) is a plant-specific transcription factor shown to promote nitrogen assimilation in Arabidopsis thaliana (Arabidopsis) even under nitrogen-deficient conditions.	Nitrogen	149-157	DNA-binding protein MNB1	Zea mays	6-10
21827189-1	2011	Pyridoxal 5"-phosphate (PLP; vitamin B(6))-catalyzed reactions have been well studied, both on enzymes and in solution, due to the variety of important reactions this cofactor catalyzes in nitrogen metabolism.	Nitrogen	189-197	pyridoxal phosphatase	Homo sapiens	24-27
21820769-0	2011	Biphenyl-3-yl alkylcarbamates as fatty acid amide hydrolase (FAAH) inhibitors: steric effects of N-alkyl chain on rat plasma and liver stability.	Nitrogen	97-98	fatty-acid amide hydrolase-like	Rattus norvegicus	61-65
9257731-3	1997	Repeated exposures of the cells to N/OFQ caused desensitization of ORL1.	Nitrogen	35-36	opioid related nociceptin receptor 1	Homo sapiens	67-71
9699005-3	1998	In order to assess the role of free radicals in cell signaling, we have studies the modulator effect of oxygen and nitrogen active species on liver methionine adenosyltransferase (MAT), a key metabolic enzyme.	Nitrogen	115-123	methionine adenosyltransferase 1A	Homo sapiens	180-183
9699005-16	1998	On the basis of the metabolic implications of liver MAT, together with the structural features accounting for the sensitivity of this enzyme to active oxygen and nitrogen species, we propose that modulation of MAT by these agents could be a mechanism to regulate the consumption of ATP in the liver, and thus preserve cellular viability under different stress conditions.	Nitrogen	162-170	methionine adenosyltransferase 1A	Homo sapiens	210-213
9472073-1	1998	The original pso3-1 mutant isolate of the yeast Saccharomyces cerevisiae exhibits a pleiotropic mutagen-sensitivity phenotype that includes sensitivity to UVA-activated 3-carbethoxypsoralen, to UVC-light, to mono- and bi-functional nitrogen mustard, to paraquat, and to cadmium; on the other hand, it shows hyper-resistance (HYR) to nitrosoguanidine when compared to established wild-type strains.	Nitrogen	232-240	ribonucleotide-diphosphate reductase subunit RNR4	Saccharomyces cerevisiae S288C	13-17
9407058-5	1997	Lectin binding and treatment with N-glycosidase F showed that PTX3 is N-glycosylated, sugars accounting for 5 kDa of the monomer mass (45 kDa).	Nitrogen	34-35	pentraxin-related protein PTX3	Cricetulus griseus	62-66
9271144-1	1997	N-Acetyl-beta-glucosaminidase (NAG), a glycosidase enzyme, present in serum, urine and the renal lysosomes is utilized clinically as an early marker for renal damage preceding the elevation of both blood urea nitrogen and creatinine.	Nitrogen	209-217	O-GlcNAcase	Homo sapiens	0-29
9271144-1	1997	N-Acetyl-beta-glucosaminidase (NAG), a glycosidase enzyme, present in serum, urine and the renal lysosomes is utilized clinically as an early marker for renal damage preceding the elevation of both blood urea nitrogen and creatinine.	Nitrogen	209-217	O-GlcNAcase	Homo sapiens	31-34
22384338-9	2011	We functionally demonstrated that an allele of the ABZ1 gene, localized in the hotspot and involved in p-aminobenzoate biosynthesis, controls the fermentation rate through modulation of nitrogen utilization.	Nitrogen	186-194	4-amino-4-deoxychorismate synthase	Saccharomyces cerevisiae S288C	51-55
9224630-6	1997	Endoglycosidase H and N-glycanase F treatment of the radiolabelled C2GnT indicated the presence of N-glycans at both potential N-glycosylation sites.	Nitrogen	22-23	glucosaminyl (N-acetyl) transferase 1	Homo sapiens	67-72
9148942-0	1997	Murine SR-BI, a high density lipoprotein receptor that mediates selective lipid uptake, is N-glycosylated and fatty acylated and colocalizes with plasma membrane caveolae.	Nitrogen	91-92	scavenger receptor class B, member 1	Mus musculus	7-12
9210490-0	1997	Domain-specific N-glycosylation of the membrane glycoprotein dipeptidylpeptidase IV (CD26) influences its subcellular trafficking, biological stability, enzyme activity and protein folding.	Nitrogen	16-17	dipeptidylpeptidase 4	Rattus norvegicus	61-83
9210490-0	1997	Domain-specific N-glycosylation of the membrane glycoprotein dipeptidylpeptidase IV (CD26) influences its subcellular trafficking, biological stability, enzyme activity and protein folding.	Nitrogen	16-17	dipeptidylpeptidase 4	Rattus norvegicus	85-89
9384596-3	1997	We show here that the Cln3 cyclin, which has a key role in the timely activation of SBF (Swi4-Swi6)- and MBF (Mbp1-Swi6)-dependent promoters in late G1, is down-regulated rapidly at a post-transcriptional level in cells deprived of the nitrogen source.	Nitrogen	236-244	SBF complex DNA-binding subunit SWI4	Saccharomyces cerevisiae S288C	89-108
9402957-3	1997	This "pseudodeficiency" allele commonly found among many reported populations (frequency approximately 0.10) is associated with two A--&gt;G transitions in cis in the arylsulfatase A gene causing the simultaneous loss of an N-glycosylation and a polyadenylation signal.	Nitrogen	224-225	arylsulfatase A	Homo sapiens	167-182
9210490-1	1997	Dipeptidyl peptidase IV (DPPIV, CD26) is an N-glycosylated type II plasma membrane protein.	Nitrogen	44-45	dipeptidylpeptidase 4	Rattus norvegicus	0-23
21712387-2	2011	A mammalian uncoordinated 119 protein (UNC119), also known as Retina Gene 4 protein (RG4), has been recently implicated in transducin transport to the OS in the dark through its interaction with the N-acylated GTP-bound transducin-alpha subunit (Galpha(t1)).	Nitrogen	40-41	interleukin 1 receptor like 1	Homo sapiens	246-255
9210490-1	1997	Dipeptidyl peptidase IV (DPPIV, CD26) is an N-glycosylated type II plasma membrane protein.	Nitrogen	44-45	dipeptidylpeptidase 4	Rattus norvegicus	25-30
9210490-1	1997	Dipeptidyl peptidase IV (DPPIV, CD26) is an N-glycosylated type II plasma membrane protein.	Nitrogen	44-45	dipeptidylpeptidase 4	Rattus norvegicus	32-36
9210490-2	1997	The primary structure of rat wild-type DPPIV contains eight potential N-glycosylation sites.	Nitrogen	70-71	dipeptidylpeptidase 4	Rattus norvegicus	39-44
9210490-3	1997	To investigate the role of N-glycosylation in the function of DPPIV, three of its asparagine residues were separately converted to glutamine by site-directed mutagenesis.	Nitrogen	27-28	dipeptidylpeptidase 4	Rattus norvegicus	62-67
9210490-4	1997	The resulting N-glycosylation mutants of rat DPPIV were studied in stable transfected Chinese hamster ovary cells.	Nitrogen	14-15	dipeptidylpeptidase 4	Rattus norvegicus	45-50
9346953-13	1997	Both 3-OST species exhibit five potential N-glycosylation sites, which account for the apparent discrepancy between the molecular masses of the encoded enzyme (approximately 34 kDa) and the previously purified enzyme (approximately 46 kDa).	Nitrogen	42-43	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	Mus musculus	5-10
20654373-1	1997	The aim of this in vitro study was to characterize the early effects of short-term exposure to low concentrations of mechlorethamine (HN2), a nitrogen mustard, on rabbit tracheal primary cultures.	Nitrogen	142-150	MT-RNR2 like 2 (pseudogene)	Homo sapiens	134-137
21797203-6	2011	The chlorine atom initiated oxidation of ethyl acetate in N(2)/O(2) diluent gave acetic acid, acetic acid anhydride, acetic formic anhydride, formaldehyde, and, in the presence of NO(x), PAN.	Nitrogen	58-62	adenosine deaminase 2	Homo sapiens	187-190
9312015-1	1997	Adenylyl transferase (ATase) is the bifunctional effector enzyme in the nitrogen assimilation cascade that controls the activity of glutamine synthetase (GS) in Escherichia coli.	Nitrogen	72-80	adenylyltransferase	Escherichia coli	0-20
9096605-10	1997	Nitrogen contents of organs increased after both GH and IGF-I treatment, and even more so after the combination treatment, reaching an increase of 30% (P &lt; .05).	Nitrogen	0-8	gonadotropin releasing hormone receptor	Rattus norvegicus	49-51
21807321-10	2011	BNP strategy was associated with a trend toward a lower blood urea nitrogen (24 mg/dL vs 29 mg/dL; P = .07); BNP strategy patients received significantly more angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, and the combination of ACE inhibitor or angiotensin receptor blocker plus beta-blockers.	Nitrogen	67-75	natriuretic peptide B	Homo sapiens	0-3
9376679-0	1997	N-glycosylation is requisite for the enzyme activity and Golgi retention of N-acetylglucosaminyltransferase III.	Nitrogen	0-1	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	76-111
9376679-2	1997	Rat GnT-III contains three potential N-glycosylation sites, which have been predicted to be Asn243, Asn261, and Asn399.	Nitrogen	37-38	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	4-11
21625719-1	2011	The introduction of hydrophobic groups (e.g. methyl) at the most adjacent sites of each and every coordinating nitrogen atom of the bipyridine pillar linker in a carboxylate-based bridging MOF could shield the metal ions from attack by water molecules, and thus enhance the water resistance of the MOF structure significantly.	Nitrogen	111-119	lysine acetyltransferase 8	Homo sapiens	189-192
9314345-6	1997	We also report based on protein sequence analysis that the amino terminal segment (which includes the site D epitope) of GpI allergens from seven different grass species is highly conserved and contains two hydroxyproline residues and an N-linked carbohydrate moiety.	Nitrogen	238-239	glucose-6-phosphate isomerase	Homo sapiens	121-124
21625719-1	2011	The introduction of hydrophobic groups (e.g. methyl) at the most adjacent sites of each and every coordinating nitrogen atom of the bipyridine pillar linker in a carboxylate-based bridging MOF could shield the metal ions from attack by water molecules, and thus enhance the water resistance of the MOF structure significantly.	Nitrogen	111-119	lysine acetyltransferase 8	Homo sapiens	298-301
9299393-2	1997	The infectivity of HIV-1 from the cells stimulated with phorbol 12-myristate 13-acetate (PMA) was suppressed by pretreatment with N-myristoyl glycinal diethylacetal (N-Myr-GOA), a potent N-myristoylation inhibitor, and the blockage of myristoylation resulted in accumulation of immature gag precursors.	Nitrogen	130-131	Pr55(Gag)	Human immunodeficiency virus 1	287-290
9257874-3	1997	ICAM-1 deficiency resulted in a striking improvement in the survival of Fas(lpr) mice (median +/- SEM survival of Fas(lpr) = 26 +/- 1.7 vs ICAM-1/Fas(lpr) = 47 +/- 2.4 wk, p &lt; 0.0001) and the increased survival was associated with delayed elevations of blood urea nitrogen levels in the ICAM-1/Fas(lpr) mice.	Nitrogen	267-275	intercellular adhesion molecule 1	Mus musculus	0-6
9226256-4	1997	Expression of FDH1 was found to be induced by choline or methylamine (used as a nitrogen source), as well as by methanol (used as a carbon source).	Nitrogen	80-88	formate dehydrogenase (NAD+)	Saccharomyces cerevisiae S288C	14-18
21593147-0	2011	Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies.	Nitrogen	54-55	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	96-117
9225822-2	1997	The receptor affinity of N-LDL, Ox-LDL, N-Lp(a), and Ox-Lp(a) was comparable (Kd, 33, 13, 24, and 13 micrograms/mL medium), whereas the maximum degradative capacity was 10.5-fold higher in N-LDL (Vmax, 1,978 ng/mg cell protein) compared with Ox-LDL (189 ng/mg).	Nitrogen	40-41	lipoprotein(a)	Homo sapiens	42-47
21511809-6	2011	ASP2 encodes for cytosolic aspartate aminotransferase (AAT), a PLP-dependent enzyme that plays a key role in carbon and nitrogen metabolism.	Nitrogen	120-128	aspartate aminotransferase 2	Arabidopsis thaliana	0-4
9306922-3	1997	In vivo ischaemia, as well as no-flow hypoxia, or N2-induced hypoxia in isolated perfused livers, reduced the activity of 5"-nucleotidase, a sensitive marker for plasma membrane damage in hepatocytes.	Nitrogen	50-52	5' nucleotidase, ecto	Rattus norvegicus	122-137
9171383-1	1997	Nitrogen catabolic gene expression in Saccharomyces cerevisiae has been reported to be regulated by three GATA family proteins, the positive regulators Gln3p and Gat1p/Nil1p and the negative regulator Dal80p/Uga43p.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	162-167
9171383-1	1997	Nitrogen catabolic gene expression in Saccharomyces cerevisiae has been reported to be regulated by three GATA family proteins, the positive regulators Gln3p and Gat1p/Nil1p and the negative regulator Dal80p/Uga43p.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	168-173
21511809-6	2011	ASP2 encodes for cytosolic aspartate aminotransferase (AAT), a PLP-dependent enzyme that plays a key role in carbon and nitrogen metabolism.	Nitrogen	120-128	aspartate aminotransferase	Arabidopsis thaliana	55-58
9171383-2	1997	We show here that a fourth member of the yeast GATA family, the Dal80p homolog Deh1p, also negatively regulates expression of some, but not all, nitrogen catabolic genes, i.e., GAP1, DAL80, and UGA4 expression increases in a deh1 delta mutant.	Nitrogen	145-153	Gzf3p	Saccharomyces cerevisiae S288C	79-84
9171383-2	1997	We show here that a fourth member of the yeast GATA family, the Dal80p homolog Deh1p, also negatively regulates expression of some, but not all, nitrogen catabolic genes, i.e., GAP1, DAL80, and UGA4 expression increases in a deh1 delta mutant.	Nitrogen	145-153	Gzf3p	Saccharomyces cerevisiae S288C	225-229
21548565-9	2011	Small changes in the enhancement of the CCNH(2), COO(-), and -CONH- group modes upon adsorption, which were consistent with the adsorption of these peptides, also occurred (with slightly different strengths) through the nitrogen and oxygen lone pair of electrons in these groups.	Nitrogen	220-228	cyclin H	Homo sapiens	40-44
9171383-4	1997	Deh1p function is demonstrable, however, only when a repressive nitrogen source such as glutamine is present; deh1 delta mutants exhibit no detectable phenotype with a poor nitrogen source such as proline.	Nitrogen	64-72	Gzf3p	Saccharomyces cerevisiae S288C	0-5
9171383-4	1997	Deh1p function is demonstrable, however, only when a repressive nitrogen source such as glutamine is present; deh1 delta mutants exhibit no detectable phenotype with a poor nitrogen source such as proline.	Nitrogen	173-181	Gzf3p	Saccharomyces cerevisiae S288C	0-5
9171427-0	1997	Role of GATA factor Nil2p in nitrogen regulation of gene expression in Saccharomyces cerevisiae.	Nitrogen	29-37	Gzf3p	Saccharomyces cerevisiae S288C	20-25
9171427-2	1997	The expression of many nitrogen-regulated genes of Saccharomyces cerevisiae requires activation by GATA factor Gln3p or Nil1p and is prevented by the presence of glutamine in the growth medium.	Nitrogen	23-31	Gat1p	Saccharomyces cerevisiae S288C	120-125
21608228-11	2011	The positive expressions of MMP-2 and MMP-9 in the XTSJD group and the OH group was significantly lower than that in the NS group (P &lt;0.01).	Nitrogen	121-123	matrix metallopeptidase 9	Mus musculus	38-43
9164946-4	1997	The predicted amino acid contained four predicted N-linked glycosylation sites and was 65% identical to the 482 amino acids comprising the coding region of the human C3aR.	Nitrogen	50-51	complement C3a receptor 1	Homo sapiens	166-170
9129466-4	1997	Estimates based on the nitrogen-free respiratory quotient (RQ) revealed fat oxidation to be significantly increased by GH (P &lt; 0.001) and IGF-I (P &lt; 0.03), whereas protein oxidation was significantly reduced (P &lt; 0.0001) by these growth factors.	Nitrogen	23-31	gonadotropin releasing hormone receptor	Rattus norvegicus	119-121
21242461-6	2011	Blood urea nitrogen (BUN) and plasma creatinine levels were elevated in the Ren-/- strain (BUN 112 +- 7 versus 23 +- 2 mg/dL and creatinine 0.53 +- 0.02 versus 0.26 +- 0.02 mg/dL), and kidney morphology was abnormal with a rudimentary inner renal medulla, cortical interstitial fibrosis, thickening of arterial walls, and abnormally shaped glomeruli.	Nitrogen	11-19	renin	Rattus norvegicus	76-79
9098894-2	1997	It is heterogeneously N-acylated by myristoyl and related fatty acyl residues that are thought to act as "calcium-myristoyl switches," whereby, in the presence of Ca2+, the N-terminal acyl group is extended away from recoverin and, in the absence of calcium, it is more closely associated with the protein.	Nitrogen	22-23	recoverin	Homo sapiens	217-226
21051484-0	2011	Hap2-3-5-Gln3 determine transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions in the yeast Saccharomyces cerevisiae.	Nitrogen	85-93	asparagine synthase (glutamine-hydrolyzing) 1	Saccharomyces cerevisiae S288C	63-67
9124536-3	1997	Both TNF and IL-1 produced weight loss, net nitrogen loss, and skeletal muscle catabolism and increased liver weight.	Nitrogen	44-52	tumor necrosis factor-like	Rattus norvegicus	5-8
21051484-3	2011	The results presented in this paper show that transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions is achieved through the action of the novel Hap2-3-5-Gln3 transcriptional regulator.	Nitrogen	107-115	asparagine synthase (glutamine-hydrolyzing) 1	Saccharomyces cerevisiae S288C	85-89
21070866-1	2011	BACKGROUND: Dietary n-3 polyunsaturated fatty acid (PUFA) deprivation increases expression of arachidonic acid (AA 20:4n-6)-selective cytosolic phospholipase A(2) (cPLA(2)) IVA and cyclooxygenase (COX)-2 in rat brain, while decreasing expression of docosahexaenoic acid (DHA 22:6n-3)-selective calcium-independent iPLA(2) VIA.	Nitrogen	20-21	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	181-203
9041240-4	1997	RESULTS: The hIFC-1 cDNA contains an open reading frame for 591 amino acids (relative molecular mass = 64,826, pI = 9.4, 12 transmembrane domains, three protein kinase C phosphorylation sites, and one N-glycosylation site) with 74% DNA and 66% amino acid sequence homologies with the mouse cDNA counterpart.	Nitrogen	22-23	solute carrier family 19 member 1	Homo sapiens	13-19
9202429-0	1997	RAS2/PKA pathway activity is involved in the nitrogen regulation of L-leucine uptake in Saccharomyces cerevisiae.	Nitrogen	45-53	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	0-4
9202429-1	1997	The aim of the present work is to study the participation of RAS2/PKA signal pathway in the nitrogen regulation of L-leucine transport in yeast cells.	Nitrogen	92-100	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	61-65
9202429-8	1997	Activation of the RAS2/PKA signalling pathway by the RAS2val19 mutation, blocks the response to a poor nitrogen source whereas inactivation of RAS2 by gene disruption, results in an increase of the same response.	Nitrogen	103-111	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	18-22
9068641-8	1997	Further indication of the importance of the RdxB and CcoP proteins was derived from studies of mutant and wild-type cells grown under anoxygenic photosynthetic and nitrogen-fixing conditions.	Nitrogen	164-172	cytochrome c oxidase accessory protein CcoG	Rhodobacter sphaeroides 2.4.1	44-48
9068641-11	1997	This effect was most pronounced when both the rdxB and the ccoP mutations were present together in cells cultured under nitrogen-fixing photosynthetic growth conditions in which spheroidenone represented approximately 90% of the total carotenoid.	Nitrogen	120-128	cytochrome c oxidase accessory protein CcoG	Rhodobacter sphaeroides 2.4.1	46-50
21374892-9	2011	In only spinal tissues, ERK 1/2 and CREB proteins in the NP+Lido group was significantly reduced to 39%, and 48% in comparison with the NP+NS group.	Nitrogen	139-141	mitogen activated protein kinase 3	Rattus norvegicus	24-31
9084603-15	1997	Together these data indicate that inhibition of N- and P/Q-type calcium current in serotonergic caudal raphe neurons is mediated by a 5-HT1A receptor via PTX-sensitive G proteins.	Nitrogen	48-49	5-hydroxytryptamine receptor 1A	Rattus norvegicus	134-140
21472589-9	2011	This type of sequestering of Pd(2+) probably reduces the efficiency of Pd(2+) ions to selectively cleave Ub because it prevents Pd(2+) anchoring to only Met or His and to an adjacent backbone amide nitrogen and forming the "activated complex" necessary for specific peptide bond cleavage.	Nitrogen	198-206	ubiquitin	Bos taurus	105-107
9231341-11	1997	That CYP 2B1 was involved in the N-demethylation of both enantiomers was also supported by results from an experiment using phenobarbitone-inducible rat-liver microsomes.	Nitrogen	33-34	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	5-12
9231341-14	1997	Immunoinhibition studies suggest, moreover, that the N-demethylation of both chlorpheniramine enantiomers is catalysed by CYP2B1, but not by CYP1A1.	Nitrogen	53-54	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	122-128
9084006-9	1997	RESULTS: Both GH and IGF-1 decreased nitrogen excretion.	Nitrogen	37-45	gonadotropin releasing hormone receptor	Rattus norvegicus	14-16
21674342-7	2011	This approach has been applied to the solid-phase synthesis of the N-linked high mannose glycosylated form of peptide T (ASTTTNYT), a fragment of the HIV-1 envelope glycoprotein gp120.	Nitrogen	67-68	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	178-183
9106207-0	1997	Gzf3p, a fourth GATA factor involved in nitrogen-regulated transcription in Saccharomyces cerevisiae.	Nitrogen	40-48	Gzf3p	Saccharomyces cerevisiae S288C	0-5
9077523-5	1997	alpha-MSH significantly reduced ischemia-induced renal damage, measured by changes in renal histology and plasma blood urea nitrogen and creatinine in mice.	Nitrogen	124-132	pro-opiomelanocortin-alpha	Mus musculus	0-9
9202429-8	1997	Activation of the RAS2/PKA signalling pathway by the RAS2val19 mutation, blocks the response to a poor nitrogen source whereas inactivation of RAS2 by gene disruption, results in an increase of the same response.	Nitrogen	103-111	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	53-57
9202429-8	1997	Activation of the RAS2/PKA signalling pathway by the RAS2val19 mutation, blocks the response to a poor nitrogen source whereas inactivation of RAS2 by gene disruption, results in an increase of the same response.	Nitrogen	103-111	Ras family GTPase RAS2	Saccharomyces cerevisiae S288C	53-57
9106207-1	1997	In Saccharomyces cerevisiae, two positive transcription factors of the GATA family, Gln3p and Nil1p/Gat1p, upregulate the expression of multiple nitrogen pathway genes via upstream 5"-GATA-3" sequences.	Nitrogen	145-153	Gat1p	Saccharomyces cerevisiae S288C	94-99
9106207-1	1997	In Saccharomyces cerevisiae, two positive transcription factors of the GATA family, Gln3p and Nil1p/Gat1p, upregulate the expression of multiple nitrogen pathway genes via upstream 5"-GATA-3" sequences.	Nitrogen	145-153	Gat1p	Saccharomyces cerevisiae S288C	100-105
22102866-6	2011	GNC and CGA1 were found to modify the expression of chloroplast localized GLUTAMATE SYNTHASE (GLU1/Fd-GOGAT), which is the primary factor controlling nitrogen assimilation in green tissue.	Nitrogen	150-158	glutamate synthase 1	Arabidopsis thaliana	74-92
9106207-6	1997	While Uga43p is active specifically under nitrogen-depression conditions, Gzf3p exerts its negative regulatory function specifically on preferred nitrogen sources: It is involved in nitrogen repression of Nil1p-dependent transcription.	Nitrogen	146-154	Gzf3p	Saccharomyces cerevisiae S288C	74-79
9106207-6	1997	While Uga43p is active specifically under nitrogen-depression conditions, Gzf3p exerts its negative regulatory function specifically on preferred nitrogen sources: It is involved in nitrogen repression of Nil1p-dependent transcription.	Nitrogen	146-154	Gzf3p	Saccharomyces cerevisiae S288C	74-79
9065690-4	1997	Ume6p, which also controls the expression of early meiotic genes, represses CAR1 expression through a sequence called URS, as a function of nitrogen availability.	Nitrogen	140-148	DNA-binding transcriptional regulator UME6	Saccharomyces cerevisiae S288C	0-5
9045801-1	1997	The expression of PRB1, the gene that encodes the precursor to the soluble vacuolar proteinase B (PrB) in Saccharomyces cerevisiae, is regulated by carbon and nitrogen sources and by growth phase.	Nitrogen	159-167	proteinase B	Saccharomyces cerevisiae S288C	18-22
9045801-1	1997	The expression of PRB1, the gene that encodes the precursor to the soluble vacuolar proteinase B (PrB) in Saccharomyces cerevisiae, is regulated by carbon and nitrogen sources and by growth phase.	Nitrogen	159-167	proteinase B	Saccharomyces cerevisiae S288C	84-96
9045801-1	1997	The expression of PRB1, the gene that encodes the precursor to the soluble vacuolar proteinase B (PrB) in Saccharomyces cerevisiae, is regulated by carbon and nitrogen sources and by growth phase.	Nitrogen	159-167	proteinase B	Saccharomyces cerevisiae S288C	98-101
9045801-8	1997	Good nitrogen sources, like ammonia, repress PRB1 transcription; mutations in URE2 do not affect this response.	Nitrogen	5-13	proteinase B	Saccharomyces cerevisiae S288C	45-49
22102866-6	2011	GNC and CGA1 were found to modify the expression of chloroplast localized GLUTAMATE SYNTHASE (GLU1/Fd-GOGAT), which is the primary factor controlling nitrogen assimilation in green tissue.	Nitrogen	150-158	glutamate synthase 1	Arabidopsis thaliana	94-98
9133635-1	1997	GDP-L-Fuc:N-acetyl-beta-D-glucosaminide:alpha1-6 fucosyltransferase (alpha1-6 FucT), which catalyzes the transfer of fucose from GDP-Fuc to N-linked type complex glycopeptides, was purified from a culture supernatant of human gastric cancer cell line MKN45.	Nitrogen	10-11	fucosyltransferase 8	Homo sapiens	69-82
21633500-2	2011	Prior studies have shown that the double N-methylated analogue of islet amyloid polypeptide (IAPP) IAPP-GI, which is a conformationally constrained IAPP analogue mimicking a non-amyloidogenic IAPP conformation, is capable of blocking cytotoxic self-assembly of Abeta.	Nitrogen	41-42	islet amyloid polypeptide	Homo sapiens	93-97
9680327-8	1997	This demonstrates the utility of nitrogen metabolism"s regulation in A. nidulans as a model system for the molecular and genetic characterization of heterologous GATA factors while also providing insights into native Aspergillus regulatory components.	Nitrogen	33-41	GATA binding protein 1	Mus musculus	162-166
9055809-2	1997	PL48 contains an open reading frame coding for a 537-amino acid protein, has multiple potential PKC, casein kinase II, and cAMP/cGMP-dependent kinase phosphorylation sites, and N-linked glycosylation sites.	Nitrogen	177-178	RHO family interacting cell polarization regulator 2	Homo sapiens	0-4
9135501-2	1997	It alkylates adenine N3 with high sequence specificity, causing no alkylation of guanine N7, the main site of alkylation of clinically used nitrogen mustards such as L-PAM.	Nitrogen	140-148	peptidylglycine alpha-amidating monooxygenase	Mus musculus	168-171
9037103-1	1997	Carbon and nitrogen regulation of UBI4, the stress-inducible polyubiquitin gene of Saccharomyces cerevisiae, was investigated using a UBI4 promoter-LacZ fusion gene (UBI4-LacZ).	Nitrogen	11-19	ubiquitin	Saccharomyces cerevisiae S288C	34-38
9062991-2	1997	The predicted results serve as an aid in interpreting experimental nitrogen adsorption data for polybutadiene (PBD) coatings on porous zirconia.	Nitrogen	67-75	activation induced cytidine deaminase	Homo sapiens	34-37
21633500-2	2011	Prior studies have shown that the double N-methylated analogue of islet amyloid polypeptide (IAPP) IAPP-GI, which is a conformationally constrained IAPP analogue mimicking a non-amyloidogenic IAPP conformation, is capable of blocking cytotoxic self-assembly of Abeta.	Nitrogen	41-42	islet amyloid polypeptide	Homo sapiens	99-103
9137808-13	1997	NMH only inhibited G6PDH and GR activity, which is fully in accord with the proposed mechanism for N-substituted derivatives of HYAM.	Nitrogen	0-1	glutathione-disulfide reductase	Homo sapiens	29-31
21633500-2	2011	Prior studies have shown that the double N-methylated analogue of islet amyloid polypeptide (IAPP) IAPP-GI, which is a conformationally constrained IAPP analogue mimicking a non-amyloidogenic IAPP conformation, is capable of blocking cytotoxic self-assembly of Abeta.	Nitrogen	41-42	islet amyloid polypeptide	Homo sapiens	99-103
9137808-14	1997	However, NDMH a double N-substituted compound, caused a strikingly different scheme of reactivity inhibition of G6PDH but not of GR, severe methaemoglobin formation, only little lipid peroxidation and some impairment of NADPH methaemoglobin reductase.	Nitrogen	9-10	glutathione-disulfide reductase	Homo sapiens	129-131
20868657-3	2010	Furthermore, we investigated whether feeding a diet of n-3 PUFA ethyl-eicosapentaenoate (E-EPA) to these mice can attenuate the MPP(+) induced changes in brain PUFA content and expression of cPLA2 and COX-2, and attenuate MPP(+) induced changes in neurotransmitters and metabolites and apoptotic markers, bax, bcl-2 and caspase-3.	Nitrogen	17-18	phospholipase A2, group IVA (cytosolic, calcium-dependent)	Mus musculus	191-196
8981998-6	1997	The sucA mutant is not a succinate auxotroph but has a reduced ability to use glutamate as a carbon or nitrogen source and an increased sensitivity to growth inhibition by acetate, relative to the parental strain.	Nitrogen	103-111	2-oxoglutarate dehydrogenase E1 component	Bradyrhizobium diazoefficiens USDA 110	4-8
9049058-1	1997	The cytotoxic and mutagenic effect of the bifunctional alkylating agent nitrogen mustard (HN2) was examined.	Nitrogen	72-80	MT-RNR2 like 2 (pseudogene)	Homo sapiens	90-93
9049649-0	1997	The role of insulin, insulin-like growth factor-I and growth hormone in counteracting dexamethasone induced nitrogen wasting in rats.	Nitrogen	108-116	gonadotropin releasing hormone receptor	Rattus norvegicus	54-68
20868657-3	2010	Furthermore, we investigated whether feeding a diet of n-3 PUFA ethyl-eicosapentaenoate (E-EPA) to these mice can attenuate the MPP(+) induced changes in brain PUFA content and expression of cPLA2 and COX-2, and attenuate MPP(+) induced changes in neurotransmitters and metabolites and apoptotic markers, bax, bcl-2 and caspase-3.	Nitrogen	17-18	prostaglandin-endoperoxide synthase 2	Mus musculus	201-206
20444205-1	2010	Nitrogen (N) metabolism was characterized in the developing ear of glutamine synthetase deficient mutants (gln1-3, gln1-4 and gln1-3/gln1-4) of maize exhibiting a reduction in kernel yield.	Nitrogen	0-8	glutamine synthetase root isozyme 3	Zea mays	107-113
9000544-7	1997	Partial digestion with N-glycosidase F showed that both potential N-glycosylation sites on PR3 were occupied and conversion of the oligosaccharide side chains into complex forms was demonstrated by acquisition of resistance to endoglycosidase H. Translocation of PR3 to granules was shown by subcellular fractionation and immunocytochemistry.	Nitrogen	23-24	proteinase 3	Homo sapiens	91-94
9000544-7	1997	Partial digestion with N-glycosidase F showed that both potential N-glycosylation sites on PR3 were occupied and conversion of the oligosaccharide side chains into complex forms was demonstrated by acquisition of resistance to endoglycosidase H. Translocation of PR3 to granules was shown by subcellular fractionation and immunocytochemistry.	Nitrogen	23-24	proteinase 3	Homo sapiens	263-266
9000544-7	1997	Partial digestion with N-glycosidase F showed that both potential N-glycosylation sites on PR3 were occupied and conversion of the oligosaccharide side chains into complex forms was demonstrated by acquisition of resistance to endoglycosidase H. Translocation of PR3 to granules was shown by subcellular fractionation and immunocytochemistry.	Nitrogen	66-67	proteinase 3	Homo sapiens	91-94
8961954-6	1996	Inhibition of N-glycosylation with an optimized concentration of tunicamycin yielded completely nonglycosylated hPTH/PTHrP receptor (approximately 60 kDa).	Nitrogen	14-15	parathyroid hormone like hormone	Homo sapiens	117-122
9058209-10	1997	Furthermore, all these changes seemed to correlate with the presence of fatty liver and the high serum free fatty acid levels, suggesting that disturbance of fatty acid metabolism affects nitrogen metabolism at least in part via altered gene expression of transcription factors such as HNF-4, C/EBP-alpha, and C/EBP-beta.	Nitrogen	188-196	CCAAT/enhancer binding protein (C/EBP), alpha	Mus musculus	293-304
20444205-1	2010	Nitrogen (N) metabolism was characterized in the developing ear of glutamine synthetase deficient mutants (gln1-3, gln1-4 and gln1-3/gln1-4) of maize exhibiting a reduction in kernel yield.	Nitrogen	0-8	glutamine synthetase root isozyme 3	Zea mays	126-132
20444205-3	2010	The ear of gln1-3 and gln1-3/gln1-4 had a higher free amino acid content and a lower C/N ratio, when compared to the wild type.	Nitrogen	87-88	glutamine synthetase root isozyme 3	Zea mays	11-17
20444205-3	2010	The ear of gln1-3 and gln1-3/gln1-4 had a higher free amino acid content and a lower C/N ratio, when compared to the wild type.	Nitrogen	87-88	glutamine synthetase root isozyme 3	Zea mays	22-28
8986142-6	1996	The most potent antagonist activity was related to good AhR binding characteristics in terms of conforming to previously predicted 14 x 12 x 5 A van der Waals dimensions and the presence of an electron-rich ring nitrogen at or near a relatively unsubstituted X-axis terminal position.	Nitrogen	212-220	aryl hydrocarbon receptor	Homo sapiens	56-59
8980671-1	1996	This study describes and characterizes the interactions of nitrogen mustard mechlorethamine (HN2) with guanine and the radiation sensitivity of guanine in the presence of HN2.	Nitrogen	59-67	MT-RNR2 like 2 (pseudogene)	Homo sapiens	93-96
20965152-3	2010	Bioinformatic analysis showed that Sidt2 is a multipass transmembrane protein that contains 10 putative N-glycosylation sites (NxS/T) and two potential tyrosine-based sorting signals (YGSF and YDTL).	Nitrogen	104-105	SID1 transmembrane family, member 2	Rattus norvegicus	35-40
8968370-4	1996	The principal finding to emerge was that the N-demethylated metabolite of DTZ was a more potent competitive inhibitor than DTZ of CYP3A2-dependent testosterone 6 beta-hydroxylation.	Nitrogen	45-46	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	130-136
8982090-3	1996	The deduced pigeon P-opsin lacks a potential N-glycosylation site in the N-terminus, but has multiple phosphorylation sites in the C-terminus, which are opposite from the characteristics of the chicken P-opsin.	Nitrogen	45-46	opsin, pineal	Gallus gallus	19-26
8991097-2	1996	Truncated GLAST-1 cDNA constructs encoding protein fragments with an increasing number of hydrophobic regions were fused to a cDNA encoding a reporter peptide with two N-glycosylation sites.	Nitrogen	20-21	solute carrier family 1 member 3 L homeolog	Xenopus laevis	10-17
9171889-8	1996	A mutant form of C8 beta in which N-glycosylation sites were eliminated was also expressed and found to be functionally similar to rC8 beta and human C8 beta.	Nitrogen	34-35	complement C8 beta chain	Homo sapiens	17-24
8798614-3	1996	The deduced amino acid sequences of CD59 homologues identified in Old and New World primates as well as in rat reveal that the motif for N-linked glycosylation at the residue corresponding to Asn18 of human CD59 is invariably conserved, despite considerable sequence divergence elsewhere in the protein.	Nitrogen	74-75	CD59 molecule	Rattus norvegicus	36-40
8798419-4	1996	Comparative sequence analysis revealed LIG-1 to be a novel integral membrane glycoprotein (1091 amino acids) containing an extracellular region (794 amino acids) with a potential signal peptide, 15 leucine-rich repeats, 3 immnunoglobulin-like domains, and 7 potential N-glycosylation sites, a transmembrane region of 23 amino acids, and a cytoplasmic region of 274 amino acids.	Nitrogen	268-269	ligase I, DNA, ATP-dependent	Mus musculus	39-44
8896280-0	1996	The S. cerevisiae nitrogen starvation-induced Yvh1p and Ptp2p phosphatases play a role in control of sporulation.	Nitrogen	18-26	tyrosine protein phosphatase PTP2	Saccharomyces cerevisiae S288C	56-61
8896280-9	1996	We also observed that expression of the PTP2 tyrosine phosphatase gene (a negative regulator of the osmosensing MAP kinase cascade), but not the PTP1 gene (also encoding a tyrosine phosphatase) was induced by nitrogen-starvation.	Nitrogen	209-217	tyrosine protein phosphatase PTP2	Saccharomyces cerevisiae S288C	40-44
20855891-1	2010	Nitrogen starvation-mediated reduction of Ypk1 is suggested to suppress translational initiation, possibly in parallel with the target of rapamycin complex 1 (TORC1) signaling.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	128-157
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase PTP2	Saccharomyces cerevisiae S288C	23-27
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase PTP2	Saccharomyces cerevisiae S288C	158-162
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase PTP2	Saccharomyces cerevisiae S288C	23-27
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase PTP2	Saccharomyces cerevisiae S288C	158-162
8878844-0	1996	A role for glucose-6-phosphate dehydrogenase in short- and long-term regulation of photosynthetic and respiratory carbon and nitrogen metabolism in nitrogen-limited Chlamydomonas reinhardtii.	Nitrogen	125-133	uncharacterized protein	Chlamydomonas reinhardtii	11-44
8878844-0	1996	A role for glucose-6-phosphate dehydrogenase in short- and long-term regulation of photosynthetic and respiratory carbon and nitrogen metabolism in nitrogen-limited Chlamydomonas reinhardtii.	Nitrogen	148-156	uncharacterized protein	Chlamydomonas reinhardtii	11-44
8884260-7	1996	The cDNA-predicted EMP-1 protein contains four putative membrane-associated domains and can be N-linked glycosylated in vitro.	Nitrogen	6-7	epithelial membrane protein 1	Mus musculus	19-24
8764331-7	1996	Among the recombinant human CYP isoforms, CYP2D6, 2B6, 3A4 and 1A2 catalyzed the 8-hydroxylation, and CYP1A2 and 3A4 were involved exclusively in the N-oxidation, whereas CYP2B6, 2C19, 1A2, 3A4 and 2D6 showed a catalytic activity for the N-demethylation, for either or both of MS enantiomers.	Nitrogen	150-151	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	171-177
20855891-1	2010	Nitrogen starvation-mediated reduction of Ypk1 is suggested to suppress translational initiation, possibly in parallel with the target of rapamycin complex 1 (TORC1) signaling.	Nitrogen	0-8	CREB regulated transcription coactivator 1	Homo sapiens	159-164
20643191-1	2010	We investigated the functional relationship between the soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) protein syntaxin 1A (syn 1A) and the dopamine transporter (DAT) by treating rat striatal tissue with Botulinum Neurotoxin C (BoNT/C) and co-transfecting syn 1A with DAT in non-neuronal cells, followed by analysis of DAT activity, phosphorylation, and regulation.	Nitrogen	64-65	solute carrier family 6 member 3	Rattus norvegicus	163-183
8757741-6	1996	Nitrogen induction of RPL1, RPL25 and RPS33 was much less dependent on the presence of the sugar, and only phosphorylated sugar caused a further increase in expression.	Nitrogen	0-8	ribosomal 60S subunit protein L5	Saccharomyces cerevisiae S288C	22-26
8757741-6	1996	Nitrogen induction of RPL1, RPL25 and RPS33 was much less dependent on the presence of the sugar, and only phosphorylated sugar caused a further increase in expression.	Nitrogen	0-8	ribosomal 60S subunit protein L25	Saccharomyces cerevisiae S288C	28-33
21541507-6	1996	The average of T/N ratio was 1.20 for PT-alpha and 1.30 for c-myc.	Nitrogen	17-18	pre T cell antigen receptor alpha	Homo sapiens	38-55
21541507-7	1996	Cases demonstrating a T/N ratio of more than 1.0 were seen in 33 (55%) and 30 (50%) cases for PT-alpha and c-myc, respectively.	Nitrogen	24-25	pre T cell antigen receptor alpha	Homo sapiens	94-102
20643191-1	2010	We investigated the functional relationship between the soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) protein syntaxin 1A (syn 1A) and the dopamine transporter (DAT) by treating rat striatal tissue with Botulinum Neurotoxin C (BoNT/C) and co-transfecting syn 1A with DAT in non-neuronal cells, followed by analysis of DAT activity, phosphorylation, and regulation.	Nitrogen	64-65	solute carrier family 6 member 3	Rattus norvegicus	185-188
8865369-12	1996	These results indicate that the CYP2E1 subfamily is the major enzyme involved in TMO N-demethylation in rat in vitro although the CYP3A2 is also involved in this transformation.	Nitrogen	85-86	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	130-136
20815339-2	2010	N-Linked glycosylation of human IL-7Ralpha enhances its binding affinity for human IL-7 300-fold versus that of the nonglycosylated receptor through an allosteric mechanism.	Nitrogen	0-1	interleukin 7 receptor	Homo sapiens	32-42
8832374-1	1996	The alkylation mechanism of guanine by nitrogen mustard (HN2) was studied by using a supermolecular modeling at the ab initio 6-31G level.	Nitrogen	39-47	MT-RNR2 like 2 (pseudogene)	Homo sapiens	57-60
8751586-7	1996	RESULTS: Compared with dogs that received kidneys preserved in the vehicle, dogs receiving the IGF-I preserved kidneys had significantly lower daily serum creatinine and blood urea nitrogen levels during the course of 5 days after transplantation.	Nitrogen	181-189	insulin like growth factor 1	Canis lupus familiaris	95-100
8755617-3	1996	To study uptake systems for mineral nitrogen, three genes homologous to Arabidopsis nitrate and ammonium transporters (AtNrt1 and AtAmt1) were isolated from a root hair-specific tomato cDNA library.	Nitrogen	36-44	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	130-136
8756339-1	1996	Alkylations at base nitrogens in DNA are removed by excision repair, the first step of which is catalyzed by the repair enzyme N-methylpurine-DNA glycosylase (MPG).	Nitrogen	20-29	N-methylpurine-DNA glycosylase	Rattus norvegicus	127-157
8756339-1	1996	Alkylations at base nitrogens in DNA are removed by excision repair, the first step of which is catalyzed by the repair enzyme N-methylpurine-DNA glycosylase (MPG).	Nitrogen	20-29	N-methylpurine-DNA glycosylase	Rattus norvegicus	159-162
8877369-0	1996	Isolation of the ALG6 locus of Saccharomyces cerevisiae required for glucosylation in the N-linked glycosylation pathway.	Nitrogen	90-91	dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase	Saccharomyces cerevisiae S288C	17-21
8634235-5	1996	The 113Cd NMR spectrum of [113Cd]HDH showed a resonance at 110 ppm, which indicates that the metal ion is bound to the protein by a combination of nitrogen and oxygen ligands.	Nitrogen	147-155	histidinol dehydrogenase, chloroplastic	Brassica oleracea	33-36
8666243-4	1996	All the important features of LAMP were conserved: (i) the deduced aa sequence reflecting a glycosyl-phosphatidylinositol (GPI)-anchor, (ii) eight putative N-linked glycosylation sites, and (iii) conserved pairs of Cys forming three internal repeats characteristic of the immunoglobulin superfamily (IgSF).	Nitrogen	156-157	limbic system associated membrane protein	Homo sapiens	30-34
20667828-3	2010	All four drugs are nitrogen-containing compounds that have nanomolar affinity for CYP46A1 in vitro yet differ in size, shape, hydrophobicity, and type of the nitrogen ligand.	Nitrogen	19-27	cytochrome P450 family 46 subfamily A member 1	Homo sapiens	82-89
8639701-9	1996	This indicated that both forms of Aky2p were N-acetylated in the wild type and that their charge difference was not caused by incomplete N-acetylation.	Nitrogen	45-46	adenylate kinase ADK1	Saccharomyces cerevisiae S288C	34-39
8692686-8	1996	By analogy with the rat pol beta structure, it is suggested that each of these HhH motifs bind DNA in a non-sequence-specific manner, via the formation of hydrogen bonds between protein backbone nitrogens and DNA phosphate groups.	Nitrogen	195-204	DNA polymerase beta	Rattus norvegicus	24-32
20554946-7	2010	Our present study demonstrates that GnT-III transfection has the potential to be an effective approach in humanizing the N-glycosylation of lepidopteran insect cells, thereby providing a possible preliminary step for the generation of complex-type glycoforms if the presence of a bisecting GlcNAc can be tolerated.	Nitrogen	121-122	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	36-43
8639592-0	1996	Amino acid sequence and carbohydrate structure of a recombinant human tissue factor pathway inhibitor expressed in Chinese hamster ovary cells: one N-and two O-linked carbohydrate chains are located between Kunitz domains 2 and 3 and one N-linked carbohydrate chain is in Kunitz domain 2.	Nitrogen	148-149	tissue factor pathway inhibitor	Homo sapiens	70-101
8639592-0	1996	Amino acid sequence and carbohydrate structure of a recombinant human tissue factor pathway inhibitor expressed in Chinese hamster ovary cells: one N-and two O-linked carbohydrate chains are located between Kunitz domains 2 and 3 and one N-linked carbohydrate chain is in Kunitz domain 2.	Nitrogen	238-239	tissue factor pathway inhibitor	Homo sapiens	70-101
8730212-0	1996	Association of alcoholism with the N-glycosylation polymorphism of pseudodeficient human arylsulfatase A.	Nitrogen	35-36	arylsulfatase A	Homo sapiens	89-104
8636059-2	1996	This gene is not expressed in media containing glutamine, and its transcription is activated in response to Gln3p in cells using glutamate as the source of nitrogen and by Nil1p in cells using urea as the source of nitrogen.	Nitrogen	156-164	Gat1p	Saccharomyces cerevisiae S288C	172-177
8636059-2	1996	This gene is not expressed in media containing glutamine, and its transcription is activated in response to Gln3p in cells using glutamate as the source of nitrogen and by Nil1p in cells using urea as the source of nitrogen.	Nitrogen	215-223	Gat1p	Saccharomyces cerevisiae S288C	172-177
20551139-3	2010	Although CD133 has been identified as a N-glycosylated protein, the specific glycosylation status of CD133 remain unclear.	Nitrogen	40-41	prominin 1	Homo sapiens	9-14
8622686-0	1996	Gat1p, a GATA family protein whose production is sensitive to nitrogen catabolite repression, participates in transcriptional activation of nitrogen-catabolic genes in Saccharomyces cerevisiae.	Nitrogen	62-70	Gat1p	Saccharomyces cerevisiae S288C	0-5
8644120-1	1996	The coumarin 7-hydroxylase of mice (Coh, CYP2A5) is known to be highly selectively inducible by both a set of heavy metals such as cobalt, indium and cerium and a variety of organic nitrogen-containing heteroaromatic compounds such as 3-amino-1,2,4-triazole, pyrazine and pyrazole.	Nitrogen	182-190	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	4-26
8644120-1	1996	The coumarin 7-hydroxylase of mice (Coh, CYP2A5) is known to be highly selectively inducible by both a set of heavy metals such as cobalt, indium and cerium and a variety of organic nitrogen-containing heteroaromatic compounds such as 3-amino-1,2,4-triazole, pyrazine and pyrazole.	Nitrogen	182-190	cytochrome P450, family 2, subfamily a, polypeptide 5	Mus musculus	41-47
8615025-1	1996	N-glycosylation of the human immunodeficiency virus type-1 envelope (Env) glycoprotein precursor (gp160) occurs by transfer of Glc3Man9GlcNAc2 onto the nascent protein.	Nitrogen	0-1	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	98-103
20930525-5	2010	These findings provide new insights into the regulation of greening and carbon-nitrogen balance by sugar metabolism through INV-E in plastids.	Nitrogen	79-87	alkaline/neutral invertase	Arabidopsis thaliana	124-129
8603584-7	1996	This effect, if apparent in other tissues, may act as a feedback mechanism to limit the local synthesis of IGF-I and could explain why IGF-I treatment had little effect on the growth rate of the sheep, although it did increase nitrogen digestibility of the feed consumed and decreased the fat content of the hind leg.	Nitrogen	227-235	insulin-like growth factor I	Ovis aries	107-112
8603584-7	1996	This effect, if apparent in other tissues, may act as a feedback mechanism to limit the local synthesis of IGF-I and could explain why IGF-I treatment had little effect on the growth rate of the sheep, although it did increase nitrogen digestibility of the feed consumed and decreased the fat content of the hind leg.	Nitrogen	227-235	insulin-like growth factor I	Ovis aries	135-140
8660283-0	1996	Soluble N-ethylmaleimide-sensitive-factor attachment protein and N-ethylmaleimide-insensitive factors are required for Ca2+-stimulated exocytosis of insulin.	Nitrogen	8-9	insulin	Mesocricetus auratus	149-156
8599930-1	1996	The cytosolic and secreted, N-glycosylated, forms of plasminogen activator inhibitor-2 (PAI-2) are generated by facultative translocation.	Nitrogen	28-29	serine (or cysteine) peptidase inhibitor, clade B, member 2	Mus musculus	53-86
20547765-5	2010	N-Sulfation and to a lesser extent O-sulfation of heparin contribute to the physical binding and optimal co-stimulation of Wnt3a.	Nitrogen	0-1	Wnt family member 3A	Homo sapiens	123-128
8599930-1	1996	The cytosolic and secreted, N-glycosylated, forms of plasminogen activator inhibitor-2 (PAI-2) are generated by facultative translocation.	Nitrogen	28-29	serine (or cysteine) peptidase inhibitor, clade B, member 2	Mus musculus	88-93
8558525-1	1996	This report concerns the synthesis and chemical characterization of novel series of N-substituted 2 beta-carbomethoxy-3 beta-(4"-iodophenyl)tropane (beta-CIT, 2) analogs and their neuropharmacological evaluation for affinity at dopamine (DAT), serotonin (5-HTT), and norepinephrine membrane transporters in rat brain tissue.	Nitrogen	84-85	solute carrier family 6 member 3	Rattus norvegicus	238-241
8558525-2	1996	N-Substituted analogs of beta-CIT with a 2 beta-carbomethoxy ester moiety showed lower DAT affinity than beta-CIT for the DAT, and some were more selective for the 5-HTT over the DAT.	Nitrogen	0-1	solute carrier family 6 member 3	Rattus norvegicus	87-90
8558525-2	1996	N-Substituted analogs of beta-CIT with a 2 beta-carbomethoxy ester moiety showed lower DAT affinity than beta-CIT for the DAT, and some were more selective for the 5-HTT over the DAT.	Nitrogen	0-1	solute carrier family 6 member 3	Rattus norvegicus	122-125
8558525-2	1996	N-Substituted analogs of beta-CIT with a 2 beta-carbomethoxy ester moiety showed lower DAT affinity than beta-CIT for the DAT, and some were more selective for the 5-HTT over the DAT.	Nitrogen	0-1	solute carrier family 6 member 3	Rattus norvegicus	122-125
9140729-5	1996	Furthermore, a mutant chimeric SK2 antibody, in which the N-glycosylation site was removed from the VH region, showed a Kd of 11 nM, almost similar to that of the original chimeric SK2 antibody, determined by Scatchard analysis with 125I-IL-6.	Nitrogen	58-59	sphingosine kinase 2	Homo sapiens	31-34
8676339-6	1996	Thus a series of N-substituted trans,trans-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)pyrroli din e-3- carboxylic acids (8) have been synthesized and evaluated for binding at ET(A) and ET(B) receptors.	Nitrogen	17-18	endothelin receptor type A	Rattus norvegicus	176-181
8845861-14	1996	Intrinsic clearance (Vmax/Km) calculations suggest that N-acetylation of p-aminobenzoic acid and 2-aminofluorene in Syrian hamsters is catalysed primarily by NAT2 (NAT2 15) in rapid acetylators but by NAT1 (NAT1 9) in slow acetylators.	Nitrogen	56-57	arylamine N-acetyltransferase 2	Mesocricetus auratus	158-162
8845861-14	1996	Intrinsic clearance (Vmax/Km) calculations suggest that N-acetylation of p-aminobenzoic acid and 2-aminofluorene in Syrian hamsters is catalysed primarily by NAT2 (NAT2 15) in rapid acetylators but by NAT1 (NAT1 9) in slow acetylators.	Nitrogen	56-57	arylamine N-acetyltransferase 2	Mesocricetus auratus	164-171
20660348-6	2010	A single-nucleotide polymorphism in the first short consensus repeat of Sle1c Crry introduced a novel N-linked glycosylation site likely responsible for this structural alteration.	Nitrogen	102-103	systematic lupus erythematosus susceptibility 1c	Mus musculus	72-77
8566220-7	1996	The testis also contained N-extended forms of two other neutral TRH-like peptides which were less hydrophobic than pGlu-Phe-Pro amide.	Nitrogen	26-27	thyrotropin releasing hormone	Oryctolagus cuniculus	64-67
8560759-6	1996	However, in mice of the H-2b haplotype, wt gp160 primed T cells which responded in vitro to a peptide containing one of the deleted N-glycosylation sites (Asn448), whereas T cells induced by gp160A123 were unable to recognize this peptide.	Nitrogen	132-133	leucyl/cystinyl aminopeptidase	Mus musculus	43-48
8720143-2	1995	In order to assess the importance of 6-O-sulfate groups in N-sulfated glucosamine (GlcNS) residues to promote FGF-1 and FGF-2 activities, various 6-O-desulfated (6-O-DS-) heparins were quantitatively examined for activity as enhancers or inhibitors of specific FGF-1- and FGF-2-induced proliferation of BALB/c3T3 clone A31 (A31) cells and the chlorate-treated cells.	Nitrogen	59-60	fibroblast growth factor 2	Mus musculus	120-125
20574568-2	2010	The resulting MOF possesses permanent porosity and exhibits stepwise sorption isotherms for O(2) and N(2) gases.	Nitrogen	101-102	lysine acetyltransferase 8	Homo sapiens	14-17
8786250-2	1995	Inhibition of N-acetylation of procainamide may prevent accumulation of excessive NAPA while maintaining therapeutic serum procainamide concentrations.	Nitrogen	14-15	NSF attachment protein alpha	Homo sapiens	82-86
7753550-4	1995	The extracellular domain of PTP-U2 contains 14 putative N-glycosylation sites and eight repeats of fibronectin type III-like motif.	Nitrogen	56-57	protein tyrosine phosphatase receptor type U	Homo sapiens	28-34
8546698-0	1996	Analysis of the role of N-glycosylation in cell-surface expression and binding properties of angiotensin II type-2 receptor of rat pheochromocytoma cells.	Nitrogen	24-25	angiotensin II receptor, type 2	Rattus norvegicus	93-123
8546698-1	1996	We previously demonstrated that the AT2 receptor is a glycoprotein containing N-linked oligosaccharide side chains and that the marked disparity between the sizes of AT2 receptors from different tissues was related to different degrees of N-glycosylation.	Nitrogen	78-79	angiotensin II receptor, type 2	Rattus norvegicus	36-39
20642449-7	2010	Quinuclidine oxidation was another pathway of importance, yielding an N-oxide (M12) which was also observed in all species.P450 2D6 and FMO1 catalyze the oxidation of the quinuclidine nitrogen.	Nitrogen	184-192	flavin containing dimethylaniline monoxygenase 1	Homo sapiens	136-140
8988371-9	1996	There are two potential N-linked glycoyslation sites in ovine IL-5.	Nitrogen	24-25	interleukin 5	Homo sapiens	62-66
20618438-0	2010	N-glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding.	Nitrogen	0-1	homeostatic iron regulator	Homo sapiens	75-78
8523579-1	1996	The second major cysteine loop of human immunodeficiency virus type 1 envelope glycoprotein gp120 contains 5 to 11 consensus N-linked glycosylation sites, which is disproportionately higher than the number of such sites found in other regions of gp120.	Nitrogen	125-126	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	92-97
7787299-7	1995	This indicated that PAS-4 contained both N- and O-linked sugar chains in concordance with the results of lectin affinity.	Nitrogen	41-42	PAS-4	Bos taurus	20-25
7880831-3	1995	These low-barrier hydrogen bonds are associated respectively with a side chain proton, the PLP pyridinium ring nitrogen proton, and the PLP Schiff base proton at the active site of the ligase.	Nitrogen	111-119	pyridoxal phosphatase	Homo sapiens	91-94
20618438-1	2010	HFE is a type 1 transmembrane protein that becomes N-glycosylated during transport to the cell membrane.	Nitrogen	51-52	homeostatic iron regulator	Homo sapiens	0-3
20618438-4	2010	Here we employed bioinformatics to identify putative N-glycosylation sites at residues N110, N130 and N234 of the human HFE protein, and used site-directed mutagenesis to create combinations of single, double or triple mutants.	Nitrogen	53-54	homeostatic iron regulator	Homo sapiens	120-123
20931875-9	2010	The results of Canonical Correspondence Analysis suggested that the abundance of 558 bp T-RF was negatively correlated with NH4(+)-N, NO3(-)-N, TN, TP and TOC, but positively correlated with TOC/TN and the water depth; the abundance of 64.5, 164, 509, and 543 bp T-RFs were positively correlated with NH4(+)-N, NO3(-)-N, TN, TOC, TOC/TN and the water depth.	Nitrogen	138-142	interleukin 5	Homo sapiens	88-92
7876241-2	1995	Most proteins that calnexin binds are N-glycosylated, and treatment of cells with tunicamycin or inhibitors of initial glucose trimming steps interferes with calnexin binding.	Nitrogen	38-39	calnexin	Homo sapiens	19-27
8787779-1	1995	Human chorionic gonadotropin (hCG) in first trimester placental cells is composed of immature alpha- and beta-subunits containing only N-linked high-mannose sugar chains.	Nitrogen	135-136	chorionic gonadotropin subunit beta 5	Homo sapiens	30-33
20543108-2	2010	Membrane fusion events that are mediated by soluble N-ethylmaleimide-sensitive-factor attachment protein receptor (SNARE) proteins are crucial, as demonstrated by patients with familial hemophagocytic lymphohistocytosis type 4 who have mutations in the SNARE protein syntaxin-11 that result in an impaired degranulation of cytotoxic cells.	Nitrogen	52-53	vesicle transport through interaction with t-SNAREs 1B	Mus musculus	115-120
7885382-2	1995	Cells were treated with either ultraviolet radiation (UV) or the chemotherapeutic alkylating agent, nitrogen mustard (HN2).	Nitrogen	100-108	MT-RNR2 like 2 (pseudogene)	Homo sapiens	118-121
7861420-0	1995	C-9 and N-substituted analogs of cis-(3aR)-(-)-2,3,3a,4,5,9b-hexahydro-3- propyl-1H-benz[e]indole-9-carboxamide: 5-HT1A receptor agonists with various degrees of metabolic stability.	Nitrogen	8-9	5-hydroxytryptamine receptor 1A	Rattus norvegicus	113-119
7849022-5	1995	To better understand the structural aspects that regulate human CD2 adhesion functions, we had previously determined the solution structure of the protein part of the N-glycosylated adhesion domain of human CD2 (hu-sCD2(105); MW approximately 13.6 kDa) by NMR spectroscopy.	Nitrogen	167-168	stearoyl-CoA desaturase 5	Homo sapiens	215-219
20543108-2	2010	Membrane fusion events that are mediated by soluble N-ethylmaleimide-sensitive-factor attachment protein receptor (SNARE) proteins are crucial, as demonstrated by patients with familial hemophagocytic lymphohistocytosis type 4 who have mutations in the SNARE protein syntaxin-11 that result in an impaired degranulation of cytotoxic cells.	Nitrogen	52-53	vesicle transport through interaction with t-SNAREs 1B	Mus musculus	253-258
20512187-1	2010	The syntheses of four new ditopic ligands (L1-4), based on N,N-functionalised 4-aminomethylpyridine, was achieved via a reductive amination methodology.	Nitrogen	59-60	immunoglobulin kappa variable 1D-17	Homo sapiens	43-47
7792749-0	1995	Antithrombotic effect of a recombinant von Willebrand factor, VCL, on nitrogen laser-induced thrombus formation in guinea pig mesenteric arteries.	Nitrogen	70-78	von Willebrand factor	Cavia porcellus	39-60
20540490-4	2010	The model can be used to predict nitrogen removal performance with different influent NH(4)(+)-N and COD concentrations and under various DO concentrations.	Nitrogen	33-41	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	101-104
7827141-1	1995	We report the effect of the ornithine transcarbamylase (OTC) transgene composed of 1.3 kb of the 5" flanking region of the rat OTC gene fused to rat OTC cDNA on urinary orotic acid excretion in OTC-deficient spf-ash (sparse-fur with abnormal skin and hair) mice during overnight-starvation and nitrogen loading.	Nitrogen	294-302	ornithine transcarbamylase	Rattus norvegicus	28-54
7827141-1	1995	We report the effect of the ornithine transcarbamylase (OTC) transgene composed of 1.3 kb of the 5" flanking region of the rat OTC gene fused to rat OTC cDNA on urinary orotic acid excretion in OTC-deficient spf-ash (sparse-fur with abnormal skin and hair) mice during overnight-starvation and nitrogen loading.	Nitrogen	294-302	ornithine transcarbamylase	Rattus norvegicus	56-59
7827141-1	1995	We report the effect of the ornithine transcarbamylase (OTC) transgene composed of 1.3 kb of the 5" flanking region of the rat OTC gene fused to rat OTC cDNA on urinary orotic acid excretion in OTC-deficient spf-ash (sparse-fur with abnormal skin and hair) mice during overnight-starvation and nitrogen loading.	Nitrogen	294-302	ornithine transcarbamylase	Rattus norvegicus	127-130
7827141-1	1995	We report the effect of the ornithine transcarbamylase (OTC) transgene composed of 1.3 kb of the 5" flanking region of the rat OTC gene fused to rat OTC cDNA on urinary orotic acid excretion in OTC-deficient spf-ash (sparse-fur with abnormal skin and hair) mice during overnight-starvation and nitrogen loading.	Nitrogen	294-302	ornithine transcarbamylase	Rattus norvegicus	127-130
7827141-1	1995	We report the effect of the ornithine transcarbamylase (OTC) transgene composed of 1.3 kb of the 5" flanking region of the rat OTC gene fused to rat OTC cDNA on urinary orotic acid excretion in OTC-deficient spf-ash (sparse-fur with abnormal skin and hair) mice during overnight-starvation and nitrogen loading.	Nitrogen	294-302	ornithine transcarbamylase	Rattus norvegicus	127-130
20530261-3	2010	Compared with wild type animals, mMCP-4-deficient mice exhibited lower proteinuria, blood creatinine, and blood urea nitrogen levels, indicating an aggravating role of mMCP-4.	Nitrogen	117-125	mast cell protease 4	Mus musculus	33-39
7587391-1	1995	Carbamyl Phosphate Synthetase I (CPS1) (EC 6.3.4.16) is a highly conserved mitochondrial enzyme catalyzing the first committed step of waste nitrogen metabolism in the urea cycle.	Nitrogen	141-149	carbamoyl-phosphate synthase 1	Homo sapiens	33-37
20379804-2	2010	Coagulation factor VIII (FVIII) is a glycoprotein which has extensive post-translational modification by N-linked glycosylation.	Nitrogen	105-106	coagulation factor VIII	Homo sapiens	25-30
7528540-9	1994	The PAPP-A subunit contains N-bound carbohydrate groups.	Nitrogen	28-29	pappalysin 1	Homo sapiens	4-10
20545859-9	2010	However, Sip1 may be sufficient for some other processes such as regulation of the nitrogen metabolism and meiosis.	Nitrogen	83-91	Sip1p	Saccharomyces cerevisiae S288C	9-13
7877727-5	1994	These observations suggest that PGF2 alpha receptor is N-linked glycosylated.	Nitrogen	55-56	prostaglandin F receptor	Rattus norvegicus	32-51
20396930-0	2010	Comparison of fast backbone dynamics at amide nitrogen and carbonyl sites in dematin headpiece C-terminal domain and its S74E mutant.	Nitrogen	46-54	dematin actin binding protein	Homo sapiens	77-84
7829092-1	1994	Xanthine dehydrogenase (XDH, EC 1.1.1.204) oxidizes a variety of purines, pterins, and other heterogenic nitrogen compounds, serving as a rate-limiting enzyme in nucleic acid degradation.	Nitrogen	105-113	xanthine dehydrogenase	Homo sapiens	0-22
7829092-1	1994	Xanthine dehydrogenase (XDH, EC 1.1.1.204) oxidizes a variety of purines, pterins, and other heterogenic nitrogen compounds, serving as a rate-limiting enzyme in nucleic acid degradation.	Nitrogen	105-113	xanthine dehydrogenase	Homo sapiens	24-27
20520733-4	2010	Here, we present the experimentally-solved topological models for FIT1 and FIT2 using N-glycosylation site mapping and indirect immunofluorescence techniques.	Nitrogen	86-87	fat storage inducing transmembrane protein 1	Homo sapiens	66-70
7520996-1	1994	Sensitivity of yeast cells to the bifunctional alkylating agent nitrogen mustard (HN2) depends on two independently operating physiological mechanisms of cellular metabolism: dynamics of uptake of HN2 via choline permease, encoded in the gene HNM1/CTR, and repair of HN2-induced DNA damage.	Nitrogen	64-72	MT-RNR2 like 2 (pseudogene)	Homo sapiens	197-200
7914890-5	1994	An earlier study had shown that a mutant arylsulfatase A containing only the second N-glycosylation site at Asn-184 folds correctly and is phosphorylated (Gieselmann, V., Schmidt, B., and von Figura, K. (1992) J. Biol.	Nitrogen	84-85	arylsulfatase A	Homo sapiens	41-56
20146544-8	2010	Interestingly, in the HSP70 homologue the GlcNAc modification is attached to an asparagine residue of a N-glycosylation motif.	Nitrogen	45-46	Heat-shock-protein-70Ab	Drosophila melanogaster	22-27
8026756-4	1994	The product of the S. cerevisiae ASP3 gene, a further member of this family, encoding the nitrogen catabolite-regulated cell-wall ASP II, has 46% overall sequence identity to ASP1.	Nitrogen	90-98	asparaginase ASP1	Saccharomyces cerevisiae S288C	175-179
20685586-3	2010	Ghrelin is unique for its post-translational modification of O-n-octanoylation at serine 3 through ghrelin O-acyltransferase, and is the only peripheral signal to enhance food intake.	Nitrogen	6-7	membrane bound O-acyltransferase domain containing 4	Homo sapiens	99-124
8195224-6	1994	Reduced and carboxymethylated (rcm) BSA, the most potent stress inducer tested, was bound most tightly by hsc70, whereas hsc70 had moderate affinity for N-methylated rcm-BSA and very little affinity for the native protein.	Nitrogen	153-154	heat shock protein family A (Hsp70) member 1 like S homeolog	Xenopus laevis	121-126
20304787-1	2010	Expression of alternative oxidase (AOX) and cyanide (CN)-resistant respiration are often highly enhanced in plants exposed to low-nitrogen (N) stress.	Nitrogen	130-138	alternative oxidase 2	Arabidopsis thaliana	14-33
8207403-0	1994	Deletion of a single N-linked glycosylation site from the transmembrane envelope protein of human immunodeficiency virus type 1 stops cleavage and transport of gp160 preventing env-mediated fusion.	Nitrogen	21-22	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	160-165
8207403-0	1994	Deletion of a single N-linked glycosylation site from the transmembrane envelope protein of human immunodeficiency virus type 1 stops cleavage and transport of gp160 preventing env-mediated fusion.	Nitrogen	21-22	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	72-75
8207403-7	1994	The results of this study indicate that N-linked glycosylation of Asn-642 in the glycoprotein produced by the pEVd1443 expression system is necessary for the correct intracellular processing of gp160 to yield surface-expressed, fusogenic gp41.	Nitrogen	40-41	glutamyl aminopeptidase	Homo sapiens	194-199
20304787-1	2010	Expression of alternative oxidase (AOX) and cyanide (CN)-resistant respiration are often highly enhanced in plants exposed to low-nitrogen (N) stress.	Nitrogen	130-138	alternative oxidase 2	Arabidopsis thaliana	35-38
8135849-1	1994	Xanthine dehydrogenase (XDH, EC 1.1.1.204) is a molybdenum iron-sulphur flavin hydroxylase which oxidizes a variety of purines, pterins and other heterogenic nitrogen compounds, serving as a rate-limiting enzyme in nucleic acid degradation.	Nitrogen	158-166	xanthine dehydrogenase	Homo sapiens	0-22
8135849-1	1994	Xanthine dehydrogenase (XDH, EC 1.1.1.204) is a molybdenum iron-sulphur flavin hydroxylase which oxidizes a variety of purines, pterins and other heterogenic nitrogen compounds, serving as a rate-limiting enzyme in nucleic acid degradation.	Nitrogen	158-166	xanthine dehydrogenase	Homo sapiens	24-27
20304787-7	2010	However, the carbon (C)/N ratios and carbohydrate levels in aox1a plants were similar to those in the WT under low-N stress.	Nitrogen	24-25	alternative oxidase 1A	Arabidopsis thaliana	60-65
20202847-1	2010	In addition to the sugar phosphotransferase system (sugar PTS) dedicated to carbohydrate uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTS(Ntr)).	Nitrogen	145-153	neurotensin receptor 1	Homo sapiens	154-158
7487356-7	1994	The number of CFU-Meg derived colonies decreased to 20% in marrow cryopreserved at -80 degrees C and to about 2% in cells stored in liquid nitrogen at -196 degrees C. These data demonstrate the advantages of bone marrow storage at -80 degrees C over freezing in liquid nitrogen at -196 degrees C. Moreover, the increased sensitivity of CFU-Meg to cryopreservation could explain, at least partially, the clinical phenomenon of protracted thrombocytopenia observed in patients transplanted with the cryopreserved bone marrow cells.	Nitrogen	269-277	protein tyrosine phosphatase non-receptor type 4	Homo sapiens	18-21
8019599-1	1994	The human erythrocyte anion transporter (band 3; AE1) has a single N-linked glycosylation site at amino residue Asn-642.	Nitrogen	67-68	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	49-52
20202847-1	2010	In addition to the sugar phosphotransferase system (sugar PTS) dedicated to carbohydrate uptake, many Gram-negative bacteria possess a so-called nitrogen PTS (PTS(Ntr)).	Nitrogen	145-153	neurotensin receptor 1	Homo sapiens	159-167
20202847-3	2010	PTS(Ntr) regulates diverse processes implicated in metabolism of nitrogen and carbon, and is essential for virulence in some bacteria.	Nitrogen	65-73	neurotensin receptor 1	Homo sapiens	0-8
8274159-8	1993	Whereas the N-hydroxylation of the guanidine involves the usual monooxygenase activity of cytochrome P450 the resultant N-hydroxyguanidine decouples monooxygenases (cytochrome P450, FMO) and the H2O2 and, above all, O2- thus formed transform the N-hydroxyguanidine further to the corresponding urea derivative.	Nitrogen	12-13	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	101-105
20056725-6	2010	This result was confirmed by other experiments including chemical inhibition by selective inhibitors and a correlation study between activities of SEN N-glucuronidation and various UGT isozymes.	Nitrogen	149-150	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	181-184
8274159-8	1993	Whereas the N-hydroxylation of the guanidine involves the usual monooxygenase activity of cytochrome P450 the resultant N-hydroxyguanidine decouples monooxygenases (cytochrome P450, FMO) and the H2O2 and, above all, O2- thus formed transform the N-hydroxyguanidine further to the corresponding urea derivative.	Nitrogen	12-13	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	176-180
8105887-3	1993	In order to better understand the structural basis for CD2-CD58-mediated adhesion and the critical role of the carbohydrate moiety in maintaining the functional stability of the molecule, we have determined the secondary structure of the N-glycosylated adhesion domain of human CD2 (hu-sCD2(105)) using NMR spectroscopy.	Nitrogen	238-239	CD58 molecule	Homo sapiens	59-63
8556161-7	1995	By reversed-phase HPLC of tryptic digested neuraminidase treated rFVIIa the glycopeptides containing the heavy chain N-glycosylated site elute as two peaks compared to the four peaks corresponding to glycopeptides with 0 to 3 N-acetyl-neuraminic acids seen for untreated rFVIIa.	Nitrogen	117-118	neuraminidase 1	Homo sapiens	43-56
7473143-7	1995	A polyclonal rabbit antibody against rat liver CYP3A1, in antibody/microsomal protein ratios varying from 1:1 to 10:1, inhibited N-demethylation of AMI to an asymptotic maximum of 60%.	Nitrogen	129-130	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	47-53
19995346-4	2010	A Tat chimaera carrying an N-glycosylation site did not become glycosylated when expressed in cells, while the chimaera was glycosylated when mechanically introduced into purified microsomes.	Nitrogen	27-28	tyrosine aminotransferase	Homo sapiens	2-5
7568152-0	1995	Role of the GATA factors Gln3p and Nil1p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes.	Nitrogen	90-98	Gat1p	Saccharomyces cerevisiae S288C	35-40
7568152-1	1995	We have isolated the NIL1 gene, whose product is an activator of the transcription of nitrogen-regulated genes, by virtue of the homology of its zinc-finger domain to that of the previously identified activator, the product of GLN3.	Nitrogen	86-94	Gat1p	Saccharomyces cerevisiae S288C	21-25
7568152-2	1995	Disruption of the chromosomal NIL1 gene enabled us to compare the effects of Gln3p and of Nil1p on the expression of the nitrogen-regulated genes GLN1, GDH2, and GAP1, coding respectively for glutamine synthetase, NAD-linked glutamate dehydrogenase, and general amino acid permease.	Nitrogen	121-129	Gat1p	Saccharomyces cerevisiae S288C	30-34
7568152-2	1995	Disruption of the chromosomal NIL1 gene enabled us to compare the effects of Gln3p and of Nil1p on the expression of the nitrogen-regulated genes GLN1, GDH2, and GAP1, coding respectively for glutamine synthetase, NAD-linked glutamate dehydrogenase, and general amino acid permease.	Nitrogen	121-129	Gat1p	Saccharomyces cerevisiae S288C	90-95
8395863-1	1993	We demonstrate that DNA-binding protein extracts can be effectively prepared directly from tissue culture cells preserved under liquid nitrogen without returning the cells to culture.	Nitrogen	135-143	zinc finger protein 763	Homo sapiens	20-39
20155902-5	2010	The CANCA experiment correlates alpha carbons with the sequentially adjacent and succeeding nitrogen and alpha carbons.	Nitrogen	92-100	proteinase 3	Homo sapiens	4-9
8330339-1	1993	We reported previously that the potent mutagen 6-aminochrysene is catalyzed principally by rat liver microsomal P4501A and P4502B enzymes to reactive metabolites that induce umu gene expression in O-acetyltransferase-over-expressing strain Salmonella typhimurium NM2009; the proposal was made that there are different mechanisms in the formation of reactive N-hydroxylated and diolepoxide metabolites by P450 enzymes (Yamazaki, H. and Shimada, T., Biochem.	Nitrogen	263-264	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	112-116
8370666-1	1993	UDP-N-acetylglucosamine:beta-D-mannoside beta 1,4 N-acetylglucosaminyltransferase III (GnT-III) [EC 2.4.1.144] catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains to produce a bisecting GlcNAc residue.	Nitrogen	4-5	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	50-85
8370666-1	1993	UDP-N-acetylglucosamine:beta-D-mannoside beta 1,4 N-acetylglucosaminyltransferase III (GnT-III) [EC 2.4.1.144] catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains to produce a bisecting GlcNAc residue.	Nitrogen	4-5	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	87-94
7629496-3	1995	5E6 is nearly identical to Ly-49C; the deduced amino acid sequence reveals a polypeptide of 266 amino acids with a molecular weight of 31,284 that contains multiple cysteine residues to explain its disulfide-linked homodimer structure and five potential N-linked glycosylation sites.	Nitrogen	254-255	killer cell lectin-like receptor, subfamily A, member 3	Mus musculus	0-3
7782289-8	1995	In each case, an N-glycosylated 27-kDa protein was generated, that, like TIMP-1 and TIMP-2, inhibited collagenase-1, stromelysin-1, and gelatinases A and B.	Nitrogen	17-18	tissue inhibitor of metalloproteinase 2	Mus musculus	84-90
7782289-8	1995	In each case, an N-glycosylated 27-kDa protein was generated, that, like TIMP-1 and TIMP-2, inhibited collagenase-1, stromelysin-1, and gelatinases A and B.	Nitrogen	17-18	matrix metallopeptidase 13	Mus musculus	102-115
7598660-1	1995	IgG is an N-glycosylated glycoprotein, and is secreted from B lymphocyte.	Nitrogen	10-11	immunoglobulin heavy chain (V7183 family)	Mus musculus	0-3
21573632-4	1993	Results indicate MCA 1315 derived OFA possesses N-glycosylated oligosaccharide chains which are high in mannose.	Nitrogen	48-49	oncofetal antigen	Mus musculus	34-37
20022931-2	2010	Human melanocortin 2 receptor (MC2R) possesses putative N-glycosylation sites in its N-terminal extracellular domain; however, to date, the role of MC2R N-glycosylation has yet to be investigated.	Nitrogen	56-57	melanocortin 2 receptor	Homo sapiens	6-29
20022931-2	2010	Human melanocortin 2 receptor (MC2R) possesses putative N-glycosylation sites in its N-terminal extracellular domain; however, to date, the role of MC2R N-glycosylation has yet to be investigated.	Nitrogen	56-57	melanocortin 2 receptor	Homo sapiens	31-35
7722685-0	1995	Abomasal nitrogen flow affects the relationship between dietary nitrogen and insulin-like growth factor-I in growing lambs.	Nitrogen	9-17	insulin-like growth factor I	Ovis aries	77-105
7722685-0	1995	Abomasal nitrogen flow affects the relationship between dietary nitrogen and insulin-like growth factor-I in growing lambs.	Nitrogen	64-72	insulin-like growth factor I	Ovis aries	77-105
8474175-7	1993	Both L268P and L322S mutants had a trans-dominant negative effect on the intracellular assembly of a non-N-myristylated, full-length (Pr55) Gag precursor expressed by a coinfecting recombinant.	Nitrogen	105-106	Pr55(Gag)	Human immunodeficiency virus 1	140-143
20022931-2	2010	Human melanocortin 2 receptor (MC2R) possesses putative N-glycosylation sites in its N-terminal extracellular domain; however, to date, the role of MC2R N-glycosylation has yet to be investigated.	Nitrogen	85-86	melanocortin 2 receptor	Homo sapiens	6-29
8510658-4	1993	Plants in which the NIA2 gene has been deleted retain only 10% of the wild-type shoot NR activity and grow normally with nitrate as the sole nitrogen source.	Nitrogen	141-149	nitrate reductase 2	Arabidopsis thaliana	20-24
7722685-9	1995	Serum IGF-I and hepatic IGF-I mRNA were correlated positively (P &lt; 0.05) with nitrogen intake and abomasal flows of nitrogen and various amino acids.	Nitrogen	81-89	insulin-like growth factor I	Ovis aries	6-11
7722685-9	1995	Serum IGF-I and hepatic IGF-I mRNA were correlated positively (P &lt; 0.05) with nitrogen intake and abomasal flows of nitrogen and various amino acids.	Nitrogen	81-89	insulin-like growth factor I	Ovis aries	24-29
7722685-9	1995	Serum IGF-I and hepatic IGF-I mRNA were correlated positively (P &lt; 0.05) with nitrogen intake and abomasal flows of nitrogen and various amino acids.	Nitrogen	119-127	insulin-like growth factor I	Ovis aries	6-11
8510658-6	1993	nia1, nia2 double mutants have only 0.5% of wild-type shoot NR activity and display very poor growth on media with nitrate as the only form of nitrogen.	Nitrogen	143-151	nitrate reductase 2	Arabidopsis thaliana	6-10
20022931-2	2010	Human melanocortin 2 receptor (MC2R) possesses putative N-glycosylation sites in its N-terminal extracellular domain; however, to date, the role of MC2R N-glycosylation has yet to be investigated.	Nitrogen	85-86	melanocortin 2 receptor	Homo sapiens	31-35
8494753-1	1993	Acute and chronic side-effects have been reported during topical treatment of mycosis fungoides with nitrogen mustard (HN2).	Nitrogen	101-109	MT-RNR2 like 2 (pseudogene)	Homo sapiens	119-122
7722685-9	1995	Serum IGF-I and hepatic IGF-I mRNA were correlated positively (P &lt; 0.05) with nitrogen intake and abomasal flows of nitrogen and various amino acids.	Nitrogen	119-127	insulin-like growth factor I	Ovis aries	24-29
20022931-4	2010	Western blot analyses performed with or without endoglycosidase H, peptide:N-glycosidase F or tunicamycin treatments and site-directed mutagenesis revealed that MC2R was glycosylated in the N-terminal domain at its two putative N-glycosylation sites (Asn(12)-Asn(13)-Thr(14) and Asn(17)-Asn(18)-Ser(19)).	Nitrogen	75-76	melanocortin 2 receptor	Homo sapiens	161-165
19572206-5	2010	Reduced Con A binding to splenocytes implied N-glycosylation modification of host proteins by hMan2c1 transgene.	Nitrogen	45-46	mannosidase alpha class 2C member 1	Homo sapiens	94-101
7613477-7	1995	The three additional glycopeptides were determined to be from a copurifying protein, apolipoprotein D, which contains potential N-linked glycosylation sites at Asn45 and Asn78.	Nitrogen	128-129	apolipoprotein D	Homo sapiens	85-101
8457553-5	1993	The Cd13-(Pi)2-MT form displays at least 24 113Cd signals between 240 and 520 ppm indicating (i) the absence of the original cluster structure of Cd7-MT, (ii) the participation of oxygen and/or nitrogen ligands besides thiolates in metal coordination, and (iii) the presence of more than one stable MT form in the sample.	Nitrogen	194-202	alanyl aminopeptidase, membrane	Homo sapiens	4-8
19962305-1	2010	A conformational analysis of kappa opioid receptor agonists, TRK-820 and U-50,488H indicated an active conformation of TRK-820 in which the C-ring was in the boat form with the 14-OH interacting with the amide nitrogen.	Nitrogen	210-218	neurotrophic receptor tyrosine kinase 1	Homo sapiens	119-122
7681148-6	1993	These glycoproteins precipitated over 75% of the lectin nitrogen added indicating that RCA1 has the ability to recognize Gal beta 1--&gt;4/3GlcNAc and/or the related residues at the non-reducing ends and at positions in the interior of the chains.	Nitrogen	56-64	von Hippel-Lindau tumor suppressor	Homo sapiens	87-91
8346988-3	1993	There were direct relationships between serum TCII levels and blood urea-nitrogen or creatinine concentrations.	Nitrogen	73-81	transcobalamin 2	Homo sapiens	46-50
7737165-7	1995	The implication of ribophorins I and II in the translocation machinery and their apparent association with the OST activity point to a close relationship between polypeptide synthesis, translocation and N-glycosylation, both spacially and temporally.	Nitrogen	203-204	ribophorin I	Sus scrofa	19-39
7766817-1	1995	Alkylation of DNA by the nitrogen mustard bis(2-chloroethyl)methylamine (mechlorethamine; HN2) gave four principal products, derived by mono-alkylation of guanine at N-7 and adenine at N-3 and by cross-linking of guanine to guanine or guanine to adenine at these positions.	Nitrogen	25-33	MT-RNR2 like 2 (pseudogene)	Homo sapiens	90-93
7532209-0	1995	N-linked glycosylation of the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA)-selective glutamate receptor channel alpha 2 subunit is essential for the acquisition of ligand-binding activity.	Nitrogen	0-1	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	30-118
7532209-1	1995	The N-linked glycosylation of the alpha 2 subunit of the mouse alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA)-selective glutamate receptor (GluR) channel was characterized.	Nitrogen	4-5	glutamate receptor, ionotropic, AMPA2 (alpha 2)	Mus musculus	63-151
7878530-1	1995	BACKGROUND: Growth hormone supplementation has been shown to stimulate muscle protein synthesis and to improve nitrogen balance in a variety of catabolic states.	Nitrogen	111-119	gonadotropin releasing hormone receptor	Rattus norvegicus	12-26
8420952-2	1993	To address these problems, a sequence of 29 amino acids encoding an internal N-glycosylation site of rabbit cytochrome P450 2C2 was attached to the N terminus of cytochrome P450 2C1.	Nitrogen	77-78	cytochrome P-450	Oryctolagus cuniculus	108-123
8424663-1	1993	The cDNA sequence of bovine thyroglobulin (bTg) predicts 14 putative N-linked glycosylation sites.	Nitrogen	6-7	thyroglobulin	Bos taurus	28-41
8466958-7	1993	(3) Determination of an experimental CsA-NS/CsA-S accumulation ratio (based upon analysis of single concentrations or processing of AUCs) is of interest only if specific assays involve not only CsA itself but also its principal metabolites.	Nitrogen	41-43	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	37-40
19786933-5	2010	Postoperative serum creatinine and urea nitrogen levels were significantly higher in patients with eGFR3 and eGFR5 abnormal levels than in patients with eGFR3 and eGFR5 normal levels.	Nitrogen	40-48	C-type lectin domain containing 14A	Homo sapiens	109-114
8416385-6	1993	An experiment which measured the ability of gp120 to bind to CD4 as an assay of the proper conformation of gp120 showed that carbohydrate chains on gp120 are not required for the interaction between gp120 and CD4 but that N-linked glycosylation is essential for generation of the proper conformation of gp120 to provide a CD4-binding site.	Nitrogen	222-223	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	107-112
8416385-6	1993	An experiment which measured the ability of gp120 to bind to CD4 as an assay of the proper conformation of gp120 showed that carbohydrate chains on gp120 are not required for the interaction between gp120 and CD4 but that N-linked glycosylation is essential for generation of the proper conformation of gp120 to provide a CD4-binding site.	Nitrogen	222-223	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	107-112
8416385-6	1993	An experiment which measured the ability of gp120 to bind to CD4 as an assay of the proper conformation of gp120 showed that carbohydrate chains on gp120 are not required for the interaction between gp120 and CD4 but that N-linked glycosylation is essential for generation of the proper conformation of gp120 to provide a CD4-binding site.	Nitrogen	222-223	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	107-112
8416385-6	1993	An experiment which measured the ability of gp120 to bind to CD4 as an assay of the proper conformation of gp120 showed that carbohydrate chains on gp120 are not required for the interaction between gp120 and CD4 but that N-linked glycosylation is essential for generation of the proper conformation of gp120 to provide a CD4-binding site.	Nitrogen	222-223	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	107-112
7873520-5	1995	In order to characterize conformational dynamics of hTGF alpha on both the fast (i.e., sub-nanosecond) and intermediate nitrogen-15 chemical-exchange (i.e., microsecond) time scales, we measured nitrogen-15 relaxation parameters at pH 7.1 +/- 0.1 and a temperature of 30 +/- 0.5 degrees C. Measurements of nitrogen-15 longitudinal (R1) and transverse (R2) relaxation rates, and 1H-15N heteronuclear NOE effects, were then interpreted using an extended Lipari-Szabo analysis [Lipari, G., &amp; Szabo, A.	Nitrogen	120-128	transforming growth factor alpha	Homo sapiens	52-62
7873520-5	1995	In order to characterize conformational dynamics of hTGF alpha on both the fast (i.e., sub-nanosecond) and intermediate nitrogen-15 chemical-exchange (i.e., microsecond) time scales, we measured nitrogen-15 relaxation parameters at pH 7.1 +/- 0.1 and a temperature of 30 +/- 0.5 degrees C. Measurements of nitrogen-15 longitudinal (R1) and transverse (R2) relaxation rates, and 1H-15N heteronuclear NOE effects, were then interpreted using an extended Lipari-Szabo analysis [Lipari, G., &amp; Szabo, A.	Nitrogen	195-203	transforming growth factor alpha	Homo sapiens	52-62
7873520-5	1995	In order to characterize conformational dynamics of hTGF alpha on both the fast (i.e., sub-nanosecond) and intermediate nitrogen-15 chemical-exchange (i.e., microsecond) time scales, we measured nitrogen-15 relaxation parameters at pH 7.1 +/- 0.1 and a temperature of 30 +/- 0.5 degrees C. Measurements of nitrogen-15 longitudinal (R1) and transverse (R2) relaxation rates, and 1H-15N heteronuclear NOE effects, were then interpreted using an extended Lipari-Szabo analysis [Lipari, G., &amp; Szabo, A.	Nitrogen	195-203	transforming growth factor alpha	Homo sapiens	52-62
7873520-16	1995	Indeed, some 40% of the backbone amide groups of hTGF alpha, including many at the interface between the two subdomains, exhibit significant nitrogen-15 chemical-exchange line broadening indicative of interconversions between multiple protein conformations on the microsecond time scale.	Nitrogen	141-149	transforming growth factor alpha	Homo sapiens	49-59
7834621-8	1995	Since the TS-PST appears to be expressed polymorphically in human populations, the finding that human TS-PST is capable of metabolically activating N-hydroxy metabolites of several carcinogenic arylamines and heterocyclic amines suggests that TS-PST may have an important role in determining interindividual susceptibility to these environmental and dietary carcinogens.	Nitrogen	148-149	sulfotransferase family 1A member 1	Homo sapiens	10-16
21076207-5	2010	In this case, the scenario employing septic-tank improvement in conjunction with sewage development may be effective for a rapid decrease of COD in locations where septic tanks are widely used under poor maintenance conditions and nitrogen pollution is not serious compared to COD.	Nitrogen	231-239	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	141-144
7834621-8	1995	Since the TS-PST appears to be expressed polymorphically in human populations, the finding that human TS-PST is capable of metabolically activating N-hydroxy metabolites of several carcinogenic arylamines and heterocyclic amines suggests that TS-PST may have an important role in determining interindividual susceptibility to these environmental and dietary carcinogens.	Nitrogen	148-149	sulfotransferase family 1A member 1	Homo sapiens	102-108
7834621-8	1995	Since the TS-PST appears to be expressed polymorphically in human populations, the finding that human TS-PST is capable of metabolically activating N-hydroxy metabolites of several carcinogenic arylamines and heterocyclic amines suggests that TS-PST may have an important role in determining interindividual susceptibility to these environmental and dietary carcinogens.	Nitrogen	148-149	sulfotransferase family 1A member 1	Homo sapiens	102-108
1479581-0	1992	Inhibition of human leukocyte elastase by N-substituted peptides containing alpha,alpha-difluorostatone residues at P1.	Nitrogen	42-43	elastase, neutrophil expressed	Homo sapiens	14-38
1284246-1	1992	A cDNA encoding the complete amino acid sequence of aminoacylase 1 (N-acylamino acid aminohydrolase, ACY-1) [EC 3.5.1.14], a dimeric metalloprotein having two Zn2+ in the molecule, which catalyzes the deacylation of N-acylated L-amino acids except L-aspartic acid, has been isolated from porcine kidney lambda gt10 cDNA library and sequenced.	Nitrogen	4-5	aminoacylase 1	Homo sapiens	52-66
1284246-1	1992	A cDNA encoding the complete amino acid sequence of aminoacylase 1 (N-acylamino acid aminohydrolase, ACY-1) [EC 3.5.1.14], a dimeric metalloprotein having two Zn2+ in the molecule, which catalyzes the deacylation of N-acylated L-amino acids except L-aspartic acid, has been isolated from porcine kidney lambda gt10 cDNA library and sequenced.	Nitrogen	4-5	aminoacylase 1	Homo sapiens	101-106
1491386-1	1992	We treated 5 patients diagnosed with rheumatoid arthritis (RA) with nitrogen mustard (HN2) and monitored clinical and immunologic variables.	Nitrogen	68-76	MT-RNR2 like 2 (pseudogene)	Homo sapiens	86-89
7759841-7	1995	However, after a further 3 weeks the renin concentration was slightly above the normal level, and this increase was accompanied by a decrease in body weight and increases in blood urea nitrogen, plasma creatinine, urinary protein and omega 3-subtype benzodiazepine receptor binding in the cerebral cortex, and by brain oedema.	Nitrogen	185-193	renin	Rattus norvegicus	37-42
7983731-6	1995	Mutations which totally or partially deleted one or the other of the two polybasic signals altered the transport of N-myristylated Gag precursor to the plasma membrane.	Nitrogen	116-117	Pr55(Gag)	Human immunodeficiency virus 1	131-134
20024105-6	2009	In contrast, the efficacy of ApAP as an inhibitor of lipid hydroperoxide biosynthesis by soybean LOX-1 (sLOX-1) increased upon incorporation of nitrogen into the ring, suggesting a different mechanism of inhibition dependent on the acidity of the phenolic O-H which may involve chelation of the catalytic non-heme iron atom.	Nitrogen	144-152	oxidized low density lipoprotein receptor 1	Homo sapiens	104-110
7749192-2	1995	Nodulin 26 is an integral membrane protein of the symbiosome membrane of nitrogen-fixing soybean nodules.	Nitrogen	73-81	nodulin-26	Glycine max	0-10
1413513-2	1992	Analysis of SH protein expressed in cells infected with RS virus or with a recombinant vaccinia virus revealed two glycosylated SH protein species, SHg and SHp, which contained N-linked carbohydrate residues.	Nitrogen	177-178	nuclear receptor subfamily 0 group B member 2	Homo sapiens	128-130
1413513-2	1992	Analysis of SH protein expressed in cells infected with RS virus or with a recombinant vaccinia virus revealed two glycosylated SH protein species, SHg and SHp, which contained N-linked carbohydrate residues.	Nitrogen	177-178	nuclear receptor subfamily 0 group B member 2	Homo sapiens	156-159
19702666-0	2009	CNI1/ATL31, a RING-type ubiquitin ligase that functions in the carbon/nitrogen response for growth phase transition in Arabidopsis seedlings.	Nitrogen	70-78	carbon/nitrogen insensitive 1	Arabidopsis thaliana	0-4
1413513-8	1992	A comparison of the deduced amino acid sequences of the human and bovine RS virus SH proteins indicated that a central hydrophobic region and the presence of potential N-linked glycosylation sites on either side of the central hydrophobic region were conserved features that may be required for the polylactosaminoglycan modification of SH.	Nitrogen	168-169	nuclear receptor subfamily 0 group B member 2	Homo sapiens	82-84
1325461-1	1992	UDP-N-acetylglucosamine: beta-D-mannoside beta-1,4N-acetylglucosaminyltransferase III (GnT-III: EC 2.4.1.144) catalyzes the addition of N-acetylglucosamine in beta 1-4 linkage to the beta-linked mannose of the trimannosyl core of N-linked sugar chains.	Nitrogen	4-5	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	87-94
8538854-5	1995	However, a progressive increase in the blood urea nitrogen and serum creatinine associated with extensive glomerular sclerosis and hypertrophy was only observed in the ADR-NaC1 group.	Nitrogen	50-58	nucleus accumbens associated 1	Rattus norvegicus	172-176
1325461-7	1992	Rat kidney GnT-III has 536 amino acids and three putative N-glycosylation sites.	Nitrogen	58-59	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	11-18
7894512-10	1995	These molecular studies shed light on the subcellular synthesis of aspartate in Arabidopsis and suggest that some of the AspAT isoenzymes may play overlapping roles in plant nitrogen metabolism.	Nitrogen	174-182	aspartate aminotransferase	Arabidopsis thaliana	121-126
19702666-0	2009	CNI1/ATL31, a RING-type ubiquitin ligase that functions in the carbon/nitrogen response for growth phase transition in Arabidopsis seedlings.	Nitrogen	70-78	carbon/nitrogen insensitive 1	Arabidopsis thaliana	5-10
7894513-9	1995	Treatment of uninfected root with L-glutamine induced the PRAT mRNA transcript suggesting that glutamine produced as a result of assimilation of fixed nitrogen is funnelled into the de novo purine biosynthesis and controls the expression of this pathway in root nodules.	Nitrogen	151-159	amidophosphoribosyltransferase, chloroplastic	Glycine max	58-62
19702666-4	2009	One line, cni1-D (carbon/nitrogen insensitive 1-dominant), was shown to have a suppressed sensitivity to C/N conditions at both the physiological and molecular level.	Nitrogen	25-33	carbon/nitrogen insensitive 1	Arabidopsis thaliana	10-14
19702666-4	2009	One line, cni1-D (carbon/nitrogen insensitive 1-dominant), was shown to have a suppressed sensitivity to C/N conditions at both the physiological and molecular level.	Nitrogen	107-108	carbon/nitrogen insensitive 1	Arabidopsis thaliana	10-14
19732381-9	2009	Protein N-glycosylation was reduced and the unfolded protein response was more activated by osmotic stress and ABA treatment in the lew3 mutant than in the wild-type.	Nitrogen	8-9	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	132-136
8848588-3	1995	Bonnet ZP3 has four potential attachment sites for N-linked sugar chains which are also conserved in human ZP3.	Nitrogen	51-52	zona pellucida glycoprotein 3	Homo sapiens	7-10
8848588-3	1995	Bonnet ZP3 has four potential attachment sites for N-linked sugar chains which are also conserved in human ZP3.	Nitrogen	51-52	zona pellucida glycoprotein 3	Homo sapiens	107-110
1352293-3	1992	The arylsulfatase A cDNA contains three potential N-glycosylation sites, two of which are utilized.	Nitrogen	22-23	arylsulfatase A	Homo sapiens	4-19
19734334-0	2009	Use of inorganic and organic nitrogen by Synechococcus spp.	Nitrogen	29-37	histocompatibility minor 13	Homo sapiens	55-58
1358850-3	1992	In this report, we studied the conformation of N-Tyr-MIF-1 in aqueous solution by conventional one-dimensional and two-dimensional (COSY and NOESY) 1H nuclear magnetic resonance spectroscopy at 300 MHz.	Nitrogen	47-48	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	53-58
1358850-5	1992	The results demonstrate that N-Tyr-MIF-1 is in slow exchange between two conformers, most likely determined by the cis and trans states of the proline residue.	Nitrogen	29-30	homocysteine inducible ER protein with ubiquitin like domain 1	Homo sapiens	35-40
7697771-3	1994	The structural requirements for the 5-HT3 receptor antagonist have been defined as an aromatic moiety, a basic nitrogen, and a linking acyl group.	Nitrogen	111-119	5-hydroxytryptamine receptor 3A	Rattus norvegicus	36-50
19734334-6	2009	In this study we used (15)N SIP methodology to assess the use of different nitrogen substrates by Synechococcus spp.	Nitrogen	75-83	histocompatibility minor 13	Homo sapiens	112-115
7858228-3	1994	Genes GS1-1 and GS1-2 exhibited distinct organ-specific responses to treatment with either nitrogen source.	Nitrogen	91-99	glutamine synthetase root isozyme 1	Zea mays	6-21
1626428-0	1992	N-linked glycosylation of proteinase B precursors of the yeast Saccharomyces cerevisiae is not required for proper targeting or processing of the enzyme.	Nitrogen	0-1	proteinase B	Saccharomyces cerevisiae S288C	26-38
1626428-1	1992	Proteinase B precursors are modified by an N-linked carbohydrate side chain at Asn 314.	Nitrogen	43-44	proteinase B	Saccharomyces cerevisiae S288C	0-12
1314648-4	1992	These results indicate that replacement of the nitrogens does not affect the kinact parameter but the Kin is increased upon removal of the exocyclic amino group and the nitrogen at the 1-position.	Nitrogen	47-56	Kin17 DNA and RNA binding protein	Homo sapiens	102-105
1314648-4	1992	These results indicate that replacement of the nitrogens does not affect the kinact parameter but the Kin is increased upon removal of the exocyclic amino group and the nitrogen at the 1-position.	Nitrogen	47-55	Kin17 DNA and RNA binding protein	Homo sapiens	102-105
7697870-9	1994	Taken together, these results suggest differential glycosylation of rat DAT occurs during postnatal development and aging; the increase is due to increases in the N-linked sugars rather than changes in either sialic acid content or the polypeptide.	Nitrogen	163-164	solute carrier family 6 member 3	Rattus norvegicus	72-75
19734334-15	2009	These data suggest that N flow in communities containing Synechococcus spp.	Nitrogen	24-25	histocompatibility minor 13	Homo sapiens	71-74
7889907-2	1994	Cox regression analysis revealed significant effects for family support (p &lt; .005), blood urea nitrogen (p &lt; .01), and age (p &lt; .005).	Nitrogen	98-106	cytochrome c oxidase subunit 8A	Homo sapiens	0-3
19812054-7	2009	Age, gender, ethnicity, body mass index, blood urea nitrogen, and creatinine affected BNP levels independently of HF.	Nitrogen	52-60	natriuretic peptide B	Homo sapiens	86-89
7730192-5	1994	The LAP contained more OM but less N and 15N than the bacterial fractions.	Nitrogen	35-36	lingual antimicrobial peptide	Bos taurus	4-7
1549584-0	1992	Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1.	Nitrogen	0-1	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	26-31
1549584-1	1992	More than 20 consensus N-linked glycosylation sites occur in the gp120 coding sequence of most isolates of human immunodeficiency virus type 1.	Nitrogen	23-24	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	65-70
1549584-6	1992	The five consensus N-linked glycosylation sites that are likely to have important roles in infectivity are all located in the amino-terminal half of gp120, indicating that the N-linked glycosylation sites that are important for infectivity of human immunodeficiency virus type 1 are not randomly distributed in gp120.	Nitrogen	19-20	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	149-154
1549584-6	1992	The five consensus N-linked glycosylation sites that are likely to have important roles in infectivity are all located in the amino-terminal half of gp120, indicating that the N-linked glycosylation sites that are important for infectivity of human immunodeficiency virus type 1 are not randomly distributed in gp120.	Nitrogen	19-20	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	311-316
1549584-6	1992	The five consensus N-linked glycosylation sites that are likely to have important roles in infectivity are all located in the amino-terminal half of gp120, indicating that the N-linked glycosylation sites that are important for infectivity of human immunodeficiency virus type 1 are not randomly distributed in gp120.	Nitrogen	176-177	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	149-154
1549584-6	1992	The five consensus N-linked glycosylation sites that are likely to have important roles in infectivity are all located in the amino-terminal half of gp120, indicating that the N-linked glycosylation sites that are important for infectivity of human immunodeficiency virus type 1 are not randomly distributed in gp120.	Nitrogen	176-177	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	311-316
7523415-6	1994	LPH alpha is neither N- nor O-glycosylated, despite the presence of 5 potential N-glycosylation sites.	Nitrogen	80-81	lactase	Homo sapiens	0-3
19585521-0	2009	Dys-regulated activation of a Src tyroine kinase Hck at the Golgi disturbs N-glycosylation of a cytokine receptor Fms.	Nitrogen	75-76	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	49-52
8000503-5	1994	These findings suggest that N-glycosylation may be involved in the secretory mechanism of the mucin-related product.	Nitrogen	28-29	LOC100508689	Homo sapiens	94-99
1735447-6	1992	When N-glycosylation was inhibited in prb1-Ala519 mutant cells by tunicamycin, a smaller molecule of about 71 kDa appeared consistent with single N-glycosylation and signal-sequence cleavage of the translocated mutant PrB molecule in the endoplasmic reticulum.	Nitrogen	5-6	proteinase B	Saccharomyces cerevisiae S288C	38-42
1735447-6	1992	When N-glycosylation was inhibited in prb1-Ala519 mutant cells by tunicamycin, a smaller molecule of about 71 kDa appeared consistent with single N-glycosylation and signal-sequence cleavage of the translocated mutant PrB molecule in the endoplasmic reticulum.	Nitrogen	146-147	proteinase B	Saccharomyces cerevisiae S288C	38-42
19585521-2	2009	We revealed that Nef disturbed N-glycosylation/trafficking of a cytokine receptor Fms in an Hck-dependent manner, a possible trigger to worsen uncontrolled immune system.	Nitrogen	17-18	HCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	92-95
1378467-7	1992	The evidence was obtained that so-called mucin "link protein", a 118-kDa glycopeptide, is a N-glycosylated fragment of fibronectin, whereas the supposedly native undergraded mucin isolated by Carlstedt et al.	Nitrogen	92-93	LOC100508689	Homo sapiens	41-46
7521361-10	1994	Finally, the ability of CD59 to enhance CD58-dependent T cell responses was shown to be dependent on N-glycosylation of CD59 at amino acid Asn18.	Nitrogen	101-102	CD58 molecule	Homo sapiens	40-44
19858358-14	2009	Instead, inhibition was observed that matched the profile of N-current inhibition from Ca(V)2.2 coexpressed with Ca(V)beta3.	Nitrogen	61-62	calcium voltage-gated channel subunit alpha1 B	Homo sapiens	87-95
1742728-1	1991	We surveyed 11 Burkitt"s lymphoma cell lines for chemosensitivity to nitrogen mustard (HN2) in order to determine whether any simple correlates to cytotoxic response might be revealed.	Nitrogen	69-77	MT-RNR2 like 2 (pseudogene)	Homo sapiens	87-90
19858358-16	2009	These findings support our previous hypothesis that Ca(V)beta2a"s palmitoyl groups directly interact with an inhibitory site on Ca(V)2.2 to block N-current inhibition by SP.	Nitrogen	146-147	calcium voltage-gated channel subunit alpha1 B	Homo sapiens	128-136
24222035-3	1994	For neurotensin, the most sensitive neuropeptide analyzed thus far in this work, the injection of 10 muL of a solution containing 320 zeptomolesy/gmL gave an [M + 3H](+3) ion at m/z 558.4 with S/N of &gt; 8:1.	Nitrogen	195-196	tripartite motif containing 37	Homo sapiens	101-104
19917352-9	2009	RESULTS: Serum creatinine and K(+), blood urea nitrogen, and aspartate aminotransferase activity decreased significantly, whereas serum Na(+) and renal function improved in the MnSOD group compared with the control and sham groups.	Nitrogen	47-55	superoxide dismutase 2	Homo sapiens	177-182
12232320-1	1994	We previously cloned and sequenced a cDNA encoding soybean ferric leghemoglobin reductase (FLbR), an enzyme postulated to play an important role in maintaining leghemoglobin in a functional ferrous state in nitrogen-fixing root nodules.	Nitrogen	207-215	leghemoglobin reductase	Glycine max	59-89
1744078-10	1991	Analysis of this mutant revealed two functions for this region: it prevents N-linked glycosylation of the serine protease domain and it allows the PrB precursor to be processed by proteinase A.	Nitrogen	76-77	proteinase B	Saccharomyces cerevisiae S288C	147-150
1794978-6	1991	These findings suggest that epsilon-amino nitrogen of Lys-301, which was introduced by amino acid substitution, occupies the 6th coordination position with the heme iron of the Lys-mutated P450, because, owing to conformation of the P450 protein, the epsilon-amino group may be located at just the right position for coordination as the internal 6th ligand.	Nitrogen	42-50	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	189-193
1794978-6	1991	These findings suggest that epsilon-amino nitrogen of Lys-301, which was introduced by amino acid substitution, occupies the 6th coordination position with the heme iron of the Lys-mutated P450, because, owing to conformation of the P450 protein, the epsilon-amino group may be located at just the right position for coordination as the internal 6th ligand.	Nitrogen	42-50	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	233-237
1918071-4	1991	The results reveal that although N-glycosylation by oligosaccharyl transferase in the endoplasmic reticulum has an absolute requirement for an hydroxyamino acid in the third amino acid residue of the glycosylation site sequence, no such specificity is observed in the binding of such peptides to PDI.	Nitrogen	33-34	prolyl 4-hydroxylase subunit beta	Homo sapiens	296-299
1918071-7	1991	We have investigated the discrepancy between this apparent lack of sequence specificity and earlier results indicating that binding of peptides to PDI was specific for N-glycosylation site sequences.	Nitrogen	168-169	prolyl 4-hydroxylase subunit beta	Homo sapiens	147-150
12232320-1	1994	We previously cloned and sequenced a cDNA encoding soybean ferric leghemoglobin reductase (FLbR), an enzyme postulated to play an important role in maintaining leghemoglobin in a functional ferrous state in nitrogen-fixing root nodules.	Nitrogen	207-215	leghemoglobin reductase	Glycine max	91-95
8055632-2	1994	Therefore, N-glucuronidation of 1- and 2-naphthylamine (1-NA and 2-NA),4-aminobiphenyl(4-ABP) and their N-hydroxy derivatives was investigated using rat and human liver microsomes and V79 cell-expressed phenol UDP-glucuronosyltransferases (UGT) of the UGT1 gene complex.	Nitrogen	11-12	amine oxidase, copper containing 1	Rattus norvegicus	89-92
8055632-4	1994	(i) N-Glucuronidation of 1- and 2-NA and of N-hydroxy-2-NA was inducible by 3-methylcholanthrene in rat liver microsomes whereas N-glucuronidation of the bulky arylamines 4-ABP and N-hydroxy-4-ABP was not.	Nitrogen	4-5	amine oxidase, copper containing 1	Rattus norvegicus	173-176
8055632-4	1994	(i) N-Glucuronidation of 1- and 2-NA and of N-hydroxy-2-NA was inducible by 3-methylcholanthrene in rat liver microsomes whereas N-glucuronidation of the bulky arylamines 4-ABP and N-hydroxy-4-ABP was not.	Nitrogen	4-5	amine oxidase, copper containing 1	Rattus norvegicus	193-196
8055632-4	1994	(i) N-Glucuronidation of 1- and 2-NA and of N-hydroxy-2-NA was inducible by 3-methylcholanthrene in rat liver microsomes whereas N-glucuronidation of the bulky arylamines 4-ABP and N-hydroxy-4-ABP was not.	Nitrogen	34-35	amine oxidase, copper containing 1	Rattus norvegicus	173-176
8055632-4	1994	(i) N-Glucuronidation of 1- and 2-NA and of N-hydroxy-2-NA was inducible by 3-methylcholanthrene in rat liver microsomes whereas N-glucuronidation of the bulky arylamines 4-ABP and N-hydroxy-4-ABP was not.	Nitrogen	34-35	amine oxidase, copper containing 1	Rattus norvegicus	193-196
19538164-4	2009	A linear skeleton with a N-containing aromatic ring attached at C3 of the top A-ring, a central pyran B-ring and a six-membered bottom C-ring with no alkylation at C7 are required for the antitumor activities of the lead compounds, a 3-pyridyl benzopyran (code name H10) and its 2-pyridyl regioisomer (code name H19).	Nitrogen	25-26	H19, imprinted maternally expressed transcript	Mus musculus	312-315
8062822-1	1994	In Saccharomyces cerevisiae, the transport of ammonium across the plasma membrane for use as a nitrogen source is mediated by at least two functionally distinct transport systems whose respective encoding genes are called MEP1 and MEP2.	Nitrogen	95-103	ammonium permease MEP1	Saccharomyces cerevisiae S288C	222-226
1820200-4	1991	The distinct site-specific distribution of the oligosaccharide structures among individual N-glycosylation sites of hCG appears to reflect primarily the influence of the surrounding protein structure on the substrate accessibility of the Golgi processing enzymes alpha-mannosidase II, GlcNAc transferase II and alpha 1,6-fucosyltransferase.	Nitrogen	91-92	chorionic gonadotropin subunit beta 5	Homo sapiens	116-119
16668258-6	1991	Treatment of nodulated plants with fixed nitrogen (urea) led to concomitant decreases in acetylene reduction activity, in leghemoglobin content, and in activities of ASC peroxidase, DHA reductase, and GSSG reductase.	Nitrogen	41-49	dehydroascorbate reductase	Glycine max	182-195
19621239-4	2009	Several structural genes of flavonoid metabolism including CHS (chalcone synthase), FLS1 (flavonol synthase 1) and ANS (anthocyanidin synthase) were induced in response to nitrogen depletion in wild type as well as in the egl3 and gl3 mutants.	Nitrogen	172-180	flavonol synthase 1	Arabidopsis thaliana	84-88
8051214-0	1994	N-ethylmaleimide-sensitive fusion protein: a trimeric ATPase whose hydrolysis of ATP is required for membrane fusion.	Nitrogen	0-1	dynein axonemal heavy chain 8	Homo sapiens	54-60
19397960-0	2009	DRDE-07 and its analogues as promising cytoprotectants to nitrogen mustard (HN-2)--an alkylating anticancer and chemical warfare agent.	Nitrogen	58-66	MT-RNR2 like 2 (pseudogene)	Homo sapiens	76-80
7517427-6	1994	All animals immunized with N-acetylated peptides PLP 217-233 and PLP 224-240 developed inflammation in the lower spinal cord, but with very low incidence of clinical EAE (1 of 12).	Nitrogen	27-28	proteolipid protein 1	Rattus norvegicus	49-52
7517427-6	1994	All animals immunized with N-acetylated peptides PLP 217-233 and PLP 224-240 developed inflammation in the lower spinal cord, but with very low incidence of clinical EAE (1 of 12).	Nitrogen	27-28	proteolipid protein 1	Rattus norvegicus	65-68
1709522-6	1991	Model building suggests that the arginine eta nitrogens and the epsilon nitrogen can form specific networks of hydrogen bonds with adjacent pairs of phosphates and that these arrangements are likely to occur near RNA loops and bulges and not within double-stranded A-form RNA.	Nitrogen	46-55	endothelin receptor type A	Homo sapiens	42-45
1709522-6	1991	Model building suggests that the arginine eta nitrogens and the epsilon nitrogen can form specific networks of hydrogen bonds with adjacent pairs of phosphates and that these arrangements are likely to occur near RNA loops and bulges and not within double-stranded A-form RNA.	Nitrogen	46-54	endothelin receptor type A	Homo sapiens	42-45
16668055-6	1991	The enzyme requires NADPH and is inhibited by sulfhydryl reagents, NADP, cytochrome c, cations, carbon monoxide, and nitrogen gas.	Nitrogen	117-125	cytochrome c	Zea mays	73-85
1990272-2	1991	The data presented show it to be required for utilization of 4-aminobutyrate as a nitrogen source and for 4-aminobutyrate-induced increases in the steady-state levels of UGA1 mRNA.	Nitrogen	82-90	4-aminobutyrate transaminase	Saccharomyces cerevisiae S288C	170-174
19397960-1	2009	Nitrogen mustard (HN-2), also known as mechlorethamine, is an alkylating anticancer agent as well as blister inducing chemical warfare agent.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	18-22
8027066-0	1994	The functions of the human insulin receptor are affected in different ways by mutation of each of the four N-glycosylation sites in the beta subunit.	Nitrogen	107-108	insulin receptor	Homo sapiens	27-43
8026756-4	1994	The product of the S. cerevisiae ASP3 gene, a further member of this family, encoding the nitrogen catabolite-regulated cell-wall ASP II, has 46% overall sequence identity to ASP1.	Nitrogen	90-98	asparaginase ASP3-1	Saccharomyces cerevisiae S288C	33-37
19346169-1	2009	We have generated a strain of mice lacking two DNA N-glycosylases of base excision repair (BER), NTH1 and NEIL1, homologs of bacterial Nth (endonuclease three) and Nei (endonuclease eight).	Nitrogen	48-49	nuclear encoded tRNA histidine 1 (anticodon ATG)	Mus musculus	97-101
8201590-3	1994	The effect of N-methylation pattern on CCK-A receptor affinity showed consistent trends for analogues in which n = 1, 2, or 3, with the di-N-methylated analogues having the highest affinity in each case.	Nitrogen	14-15	cholecystokinin A receptor	Rattus norvegicus	39-53
8183913-3	1994	Intravenous injection of recombinant human HGF into mice remarkably suppressed increases in blood urea nitrogen and serum creatinine caused by administration of cisplatin, a widely used antitumor drug, or HgCl2, thereby indicating that HGF strongly prevented the onset of acute renal dysfunction.	Nitrogen	103-111	hepatocyte growth factor	Homo sapiens	43-46
1368673-1	1991	Structural requirements of N-blocked L-proline derivatives as specific inhibitors for prolyl endopeptidase were investigated using a series of substrate analogs.	Nitrogen	27-28	prolyl endopeptidase	Homo sapiens	86-106
1987791-4	1991	The CIR rats were anorexic, hypermetabolic, relatively hyperglycemic, and had raised blood urea nitrogen with comparable creatinine levels when compared with similarly wasted PFR.	Nitrogen	96-104	corepressor interacting with RBPJ, 1	Rattus norvegicus	4-7
1953353-3	1991	Using a liver microsomal system to produce .CCl3 (microsomes + NADPH + CCl4 under nitrogen), the attack of PheMeAc did not result in I or II formation, but in production of benzene.	Nitrogen	82-90	C-C motif chemokine ligand 3	Rattus norvegicus	44-48
19534555-7	2009	The finding that BHMT does not tolerate a true betaine mimic within these inhibitors, especially the nitrogen atom, is surprising and evokes questions about putative conformational changes of BHMT upon the binding of the substrates/products and inhibitors.	Nitrogen	101-109	betaine--homocysteine S-methyltransferase	Homo sapiens	17-21
1991473-2	1991	hLH alpha (N-glycosylated at Asn52 and Asn78) and hLH beta (N-glycosylated at Asn30).	Nitrogen	11-12	glycoprotein hormones, alpha polypeptide	Homo sapiens	0-9
16667955-1	1991	By using a peptide (CK-15) based on the COOH-terminal sequence of nodulin-26, we have demonstrated the presence of a Ca(2+)-dependent protein kinase in soluble as well as particulate fractions of nitrogen-fixing soybean (Glycine max) root nodules.	Nitrogen	196-204	nodulin-26	Glycine max	66-76
16667955-9	1991	Overall, the results show the existence of a Ca(2+)-dependent and calmodulin/lipid-independent enzyme in nitrogen-fixing soybean root nodules and suggest that nodulin-26 is a substrate for Ca(2+)-dependent phosphorylation.	Nitrogen	105-113	nodulin-26	Glycine max	159-169
2125112-6	1990	In support of this hypothesis, electron microscopic studies of mus308 mutant flies that had been exposed to nitrogen mustard revealed an increased frequency of mitochondrial abnormalities.	Nitrogen	108-116	DNA polymerase theta	Drosophila melanogaster	63-69
2082620-2	1990	To address the possible role of N-glycosylation of HIV-1 gp120 in binding CD4, we mutated different conserved N-glycosylation site Asn-residues in the vicinity of the putative CD4 binding site, as single mutations or in combinations.	Nitrogen	32-33	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	57-62
16667826-3	1990	In this paper, we report rapid induction (in soybean nodules) and exceptionally high activities (in nodules of eight species of N(2)-fixing plants) of pentose phosphate pathway and pyrroline-5-carboxylate reductase.	Nitrogen	128-129	pyrroline-5-carboxylate reductase	Glycine max	181-214
2208589-1	1990	Previous studies have demonstrated that three cancer chemotherapeutic compounds of the nitrogen mustard class, melphalan (L-PAM), nitrogen mustard (HN2) and chlorambucil (CBC), each generated DNA lesions that prematurely terminate in vitro transcription.	Nitrogen	130-138	MT-RNR2 like 2 (pseudogene)	Homo sapiens	148-151
16667714-0	1990	Light Induction and the Effect of Nitrogen Status upon the Activity of Carbonic Anhydrase in Maize Leaves.	Nitrogen	34-42	carbonic anhydrase	Zea mays	71-89
16667714-1	1990	The regulation of carbonic anhydrase (CA) activity in maize (Zea mays L.) leaves by light and nitrogen nutrition was determined.	Nitrogen	94-102	carbonic anhydrase	Zea mays	18-36
16667714-1	1990	The regulation of carbonic anhydrase (CA) activity in maize (Zea mays L.) leaves by light and nitrogen nutrition was determined.	Nitrogen	94-102	carbonic anhydrase	Zea mays	38-40
2397884-4	1990	The mus308 mutants were originally distinguished from all other mutagen-sensitive mutants of Drosophila because they exhibit hypersensitivity to the DNA cross-linking agent nitrogen mustard without expressing a concurrent sensitivity to the monofunctional agent methyl methanesulfonate.	Nitrogen	173-181	DNA polymerase theta	Drosophila melanogaster	4-10
8138587-3	1994	Sensitivity to tunicamycin indicated that N-linked post-translational modifications to this 43 kDa core species generated the full complement of 50 kDa (intermediate) and 52 kDa (mature) p52(PAI-1) glycosylated isoforms.	Nitrogen	42-43	similar to Mitochondrial processing peptidase beta subunit, mitochondrial precursor (Beta-MPP; P-52)	Rattus norvegicus	187-190
8274159-0	1993	Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative.	Nitrogen	26-27	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	11-15
8269638-4	1993	In contrast, UGT1*6 lacked activity towards the dihydrodiols and metabolized a more limited range of monophenols, namely 4-,5-,8- and 12-hydroxyB[a]P. Both UGT2B7 and UGT1*6 glucuronidated N, 1-,3- and 8-hydroxyAAF, but 5-hydroxyAAF was metabolised only by UGT1*6.	Nitrogen	189-190	UDP glucuronosyltransferase family 1 member A6	Homo sapiens	13-19
8301235-0	1993	Functional role of N-linked glycosylation in human hepatic lipase: asparagine-56 is important for both enzyme activity and secretion.	Nitrogen	19-20	lipase C, hepatic type	Homo sapiens	51-65
8301235-3	1993	Human HL is a glycoprotein and its predicted amino acid sequence contains four putative N-linked glycosylation sites at Asn residues 20, 56, 340, and 375.	Nitrogen	88-89	hes family bHLH transcription factor 1	Homo sapiens	6-8
8246977-11	1993	Further, in a cha4 mutant strain which is unable to grow with serine or threonine as the sole nitrogen source, the function of UAS1CHA, as well as that of UAS2CHA, is obstructed.	Nitrogen	94-102	Cha4p	Saccharomyces cerevisiae S288C	14-18
7504734-8	1993	The nitrogen atom of the central heterocycle of 11f is postulated to engage in hydrogen-bond formation with a donor moiety in the PGI2 receptor protein, an interaction not available to 26 due to the markedly different topology.	Nitrogen	4-12	prostaglandin I2 receptor	Homo sapiens	130-143
8281144-6	1993	Despite this anomalous location in yeast, human ornithine-delta-aminotransferase complemented the phenotype of the mutant strain, restoring its ability to utilize ornithine as a sole nitrogen source.	Nitrogen	183-191	ornithine aminotransferase	Homo sapiens	48-80
8286122-5	1993	Membrane vesicles obtained from capacitated sperm by nitrogen cavitation retain b-ZP3 binding sites as determined by an enzyme-linked method employing alkaline phosphatase-conjugated strepavidin.	Nitrogen	53-61	zona pellucida glycoprotein 3	Homo sapiens	82-85
7505459-1	1993	We recently isolated and characterized the 24 kDa and N-glycosylated 28 kDa insulin-like growth factor binding protein-4 (rIGFBP-4) from the B104s rat neuronal cell line (Endocrinology, 129 (1991) 1009-1115).	Nitrogen	54-55	insulin-like growth factor binding protein 4	Rattus norvegicus	122-130
8411286-8	1993	This may diminish hepatic ureagenesis and spare amino acids for peripheral protein synthesis and thereby explain, at least in part, the ability of growth hormone to promote positive nitrogen balance in catabolic states.	Nitrogen	182-190	gonadotropin releasing hormone receptor	Rattus norvegicus	147-161
8103677-10	1993	Thus, chemical inhibition of protein N-myristoylation with HMA is an effective method for reducing the amount of p56lck available at the plasma membrane for signal transduction.	Nitrogen	37-38	lymphocyte protein tyrosine kinase	Mus musculus	113-119
8395007-5	1993	The morphologic and physiological properties caused by elm1, elm2, and elm3 mutations closely mimic pseudohyphal growth occurring in conditions of nitrogen starvation.	Nitrogen	147-155	protein kinase HSL1	Saccharomyces cerevisiae S288C	61-65
8395007-6	1993	Therefore, we propose that absence of ELM1, ELM2, or ELM3 function causes constitutive execution of the pseudohyphal differentiation pathway that occurs normally in conditions of nitrogen starvation.	Nitrogen	179-187	protein kinase HSL1	Saccharomyces cerevisiae S288C	44-48
8395007-7	1993	Supporting this hypothesis, heterozygosity at the ELM2 or ELM3 locus significantly stimulated the ability to form pseudohyphae in response to nitrogen starvation.	Nitrogen	142-150	protein kinase HSL1	Saccharomyces cerevisiae S288C	50-54
8349699-7	1993	Using site-directed mutagenesis, we determined that there is an additional site of N-glycosylation in murine PGH synthase-2 located at Asn580.	Nitrogen	83-84	prostaglandin-endoperoxide synthase 2	Mus musculus	109-123
8349699-8	1993	This site is N-glycosylated in about 50% of PGH synthase-2 molecules, resulting in two peptide bands on SDS-polyacrylamide gel electrophoresis (72 and 74 kDa).	Nitrogen	13-14	prostaglandin-endoperoxide synthase 2	Mus musculus	44-58
8513978-1	1993	Two N-linked sites of glycosylation in the insulin receptor were examined for their contribution to insulin binding, tyrosine kinase activity, and receptor biosynthesis.	Nitrogen	4-5	insulin receptor	Homo sapiens	43-59
8464905-3	1993	Tunicamycin and pulse-chase experiments revealed that the mature protein was processed by N-linked glycosylation of a 145-kDa erbB-3 core polypeptide.	Nitrogen	90-91	erb-b2 receptor tyrosine kinase 3	Homo sapiens	126-132
7681247-3	1993	The amino acid sequence of 59 kD bone sialoprotein deduced from the cDNA revealed that the entire protein consisted of 352 amino acid residues, including a signal peptide of 18 amino acid residues, and contained three possible N-glycosylation sites.	Nitrogen	70-71	cysteine-rich secretory protein 3	Rattus norvegicus	38-50
8437218-4	1993	Mutants carrying Asn--&gt;Asp mutations at each of the two consensus signals for N-linked glycosylation in the N-terminal domain of SFFVAP-L env (gs1 and gs2), the gs1-2- double mutant, and the gs0 quadruple mutant (mutated at all four signals utilized for N-linked glycosylation in SFFVAP-L env) were made.	Nitrogen	111-112	pseudouridine 5'-phosphatase	Homo sapiens	146-149
8450831-0	1993	N-hydroxylation of benzamidine to benzamidoxime by a reconstituted cytochrome P-450 oxidase system from rabbit liver: involvement of cytochrome P-450 IIC3.	Nitrogen	0-1	cytochrome P-450	Oryctolagus cuniculus	67-83
8382034-4	1993	We report, based on binding and activity data from 10 replacement analogs, that the imidazole ring of His1 furnishes an aromatic determinant for receptor binding affinity and that its protonatable imidazole nitrogen is important for transduction.	Nitrogen	207-215	viral integration site 1	Homo sapiens	102-106
8435067-1	1993	N-linked glycosylation is one of the important events in the post-translational modification of human lysosomal alpha-glucosidase.	Nitrogen	0-1	alpha glucosidase	Homo sapiens	102-129
8381072-10	1993	In conclusion, rat CGRP receptors with tissue-specific N-glycosylation but indistinguishable protein molecular mass have been identified in the cerebellum, brainstem, spinal cord, liver, and spleen.	Nitrogen	55-56	calcitonin-related polypeptide alpha	Rattus norvegicus	19-23
8420926-8	1993	However, if the consensus sequence for N-linked glycosylation at Asn-173 is altered by substitution of Thr-175 with Ala (instead of Asn-173 to Gln), the resulting receptor binds hCG with high affinity although it is still impaired in its ability to be expressed at the plasma membrane.	Nitrogen	39-40	hypertrichosis 2 (generalised, congenital)	Homo sapiens	178-181
8420926-9	1993	Furthermore, if all consensus sequences for N-linked glycosylation are mutated collectively while maintaining Asn-173 (by substituting Thr-175 with Ala instead of Asn-173 to Gln), the resulting deglycosylated receptor, although not expressed on the plasma membrane, binds hCG with high affinity.	Nitrogen	44-45	hypertrichosis 2 (generalised, congenital)	Homo sapiens	272-275
8425548-0	1993	Homology of pyridoxal-5"-phosphate-dependent aminotransferases with the cobC (cobalamin synthesis), nifS (nitrogen fixation), pabC (p-aminobenzoate synthesis) and malY (abolishing endogenous induction of the maltose system) gene products.	Nitrogen	106-114	NFS1 cysteine desulfurase	Homo sapiens	100-104
8425548-1	1993	Bacterial deletion mutants have indicated that the gene products of cobC, nifS, pabC and malY participate in important metabolic pathways, i.e. cobalamin synthesis, nitrogen fixation, synthesis of p-aminobenzoate and the regulation of the maltose system, respectively.	Nitrogen	165-173	NFS1 cysteine desulfurase	Homo sapiens	74-78
8416917-5	1993	In the presence of N-fMet-tRNAfMet and poly(A,U,G) or in the presence of N-acetyl-Phe-tRNAPhe and poly(U), initiation factor IF2 causes an additional decrease of the uncoupled EF-G GTPase activity.	Nitrogen	19-20	eukaryotic translation initiation factor 5B	Homo sapiens	125-128
8372540-0	1993	The influence of lead ions on nitrogen metabolism of lupin embryos cultivated in vitro.	Nitrogen	30-38	5'-nucleotidase, cytosolic IIIA	Homo sapiens	53-58
8482489-6	1993	These results suggest that it is possible to enhance the binding of the permanently charged trimethylammonium analog of chlorpromazine by the addition of a functional group near the quaternary nitrogen which is capable of forming a hydrogen bond with the D2 dopamine receptor.	Nitrogen	193-201	dopamine receptor D2	Homo sapiens	255-275
19302292-6	2009	The pancreatic adenocarcinoma up-regulated factor was secreted into the culture medium of pancreatic adenocarcinoma up-regulated factor-overexpressing Chinese hamster ovary cells, had an apparent molecular mass of approximately 25 kDa, and was N-glycosylated.	Nitrogen	244-245	zymogen granule protein 16B	Homo sapiens	4-49
19302292-6	2009	The pancreatic adenocarcinoma up-regulated factor was secreted into the culture medium of pancreatic adenocarcinoma up-regulated factor-overexpressing Chinese hamster ovary cells, had an apparent molecular mass of approximately 25 kDa, and was N-glycosylated.	Nitrogen	244-245	zymogen granule protein 16B	Homo sapiens	90-135
8431558-2	1993	This study demonstrates that the two light chains were both N-glycosylated with glycosyl residues of different sizes, one of which was sensitive to neuraminidase and the other insensitive.	Nitrogen	60-61	neuraminidase 1	Homo sapiens	148-161
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	4-aminobutyrate transaminase	Saccharomyces cerevisiae S288C	38-42
19251272-5	2009	HRTEM and N(2) adsorption-desorption isotherms reveal that the hollow microspheres have numerous nanopores in the walls with a broad distribution in the range of 2 to 80 nm, which results in a high BET surface (67.6 m(2)/g) and pores volume (0.14 cm(3)/g).	Nitrogen	10-14	delta/notch like EGF repeat containing	Homo sapiens	198-201
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	proline permease PUT4	Saccharomyces cerevisiae S288C	68-72
8423765-13	1993	Both CYP1A2 and CYP3A4 catalyzed N-dealkylation of propafenone, with specific activities of 0.32 pmol/min/pmol of P450 and 0.16 pmol/min/pmol of P450, respectively.	Nitrogen	33-34	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	114-118
8423765-13	1993	Both CYP1A2 and CYP3A4 catalyzed N-dealkylation of propafenone, with specific activities of 0.32 pmol/min/pmol of P450 and 0.16 pmol/min/pmol of P450, respectively.	Nitrogen	33-34	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	145-149
1458473-10	1992	Further, preferential repair of nitrogen mustard-induced N-alkylpurines were detected in a single copy of the essential active dihydrofolate reductase gene as compared to a downstream noncoding region.	Nitrogen	32-40	dihydrofolate reductase	Cricetulus griseus	127-150
1460044-4	1992	These investigations provided evidence for the existence of two forms of brush border LPH, an N-glycosylated molecule (LPHN) and an N- and O-glycosylated molecule (LPHN/O).	Nitrogen	94-95	lactase	Homo sapiens	86-89
1460044-4	1992	These investigations provided evidence for the existence of two forms of brush border LPH, an N-glycosylated molecule (LPHN) and an N- and O-glycosylated molecule (LPHN/O).	Nitrogen	122-123	lactase	Homo sapiens	86-89
19273591-4	2009	This could explain the observed decrease in both the basal and rapamycin-induced expression of several genes subjected to nitrogen catabolite repression (GAT1, MEP1, and GLN1) and stress response element (STRE)-driven promoters.	Nitrogen	122-130	Gat1p	Saccharomyces cerevisiae S288C	154-158
16653241-0	1992	Glutamine Induces the N-Dependent Accumulation of mRNAs Encoding Phosphoenolpyruvate Carboxylase and Carbonic Anhydrase in Detached Maize Leaf Tissue.	Nitrogen	22-23	carbonic anhydrase	Zea mays	101-119
16653241-1	1992	We have used detached leaves to study the N-dependent control of expression of phosphoenolpyruvate carboxylase (PEPC) and carbonic anhydrase (CA) genes in maize (Zea mays L. cv Golden Cross Bantam T51).	Nitrogen	42-43	carbonic anhydrase	Zea mays	122-140
16653241-1	1992	We have used detached leaves to study the N-dependent control of expression of phosphoenolpyruvate carboxylase (PEPC) and carbonic anhydrase (CA) genes in maize (Zea mays L. cv Golden Cross Bantam T51).	Nitrogen	42-43	carbonic anhydrase	Zea mays	142-144
16653241-2	1992	Following supplementation with an N-source and zeatin, PEPC and CA mRNA levels increased in leaves detached from N-deficient maize plants.	Nitrogen	34-35	carbonic anhydrase	Zea mays	64-66
16653241-4	1992	Glutamine levels in detached maize leaves treated with various N sources in the presence or absence of MSX correlated with the levels of PEPC and CA mRNA.	Nitrogen	63-64	carbonic anhydrase	Zea mays	146-148
19273591-4	2009	This could explain the observed decrease in both the basal and rapamycin-induced expression of several genes subjected to nitrogen catabolite repression (GAT1, MEP1, and GLN1) and stress response element (STRE)-driven promoters.	Nitrogen	122-130	ammonium permease MEP1	Saccharomyces cerevisiae S288C	160-164
2354450-3	1990	infusions of the same sublethal daily dose of tumor necrosis factor (TNF) results in decreased food intake and decreased nitrogen balance compared to saline-treated control rats.	Nitrogen	121-129	tumor necrosis factor-like	Rattus norvegicus	46-67
19185068-5	2009	Thioredoxin-mediated redox control appears to be a feature of the central pathways for assimilation and storage of carbon, sulphur and nitrogen, as well as for translation and protein folding.	Nitrogen	135-143	thioredoxin H-type 1	Arabidopsis thaliana	0-11
2354450-3	1990	infusions of the same sublethal daily dose of tumor necrosis factor (TNF) results in decreased food intake and decreased nitrogen balance compared to saline-treated control rats.	Nitrogen	121-129	tumor necrosis factor-like	Rattus norvegicus	69-72
2354450-4	1990	After 4 days of treatment, rats treated with intermittent bolus doses of TNF develop tolerance to the nutritional effects and consume normal amounts of food and have nitrogen balance similar to those of saline treated rats.	Nitrogen	166-174	tumor necrosis factor-like	Rattus norvegicus	73-76
2354450-10	1990	Continuous TNF infusion reduced total body nitrogen and potassium while pair feeding did not reduce potassium and reduced nitrogen to a lesser degree.	Nitrogen	43-51	tumor necrosis factor-like	Rattus norvegicus	11-14
2354450-12	1990	Twice a day administration of TNF resulted in lesser changes in carcass water, solid, nitrogen, lipid, and potassium than continuous infusion of the same dose of TNF.	Nitrogen	86-94	tumor necrosis factor-like	Rattus norvegicus	30-33
1505923-7	1992	By inhibition of the N-glycosylation using tunicamycin, rat C1-esterase inhibitor was identified as a glycoprotein.	Nitrogen	21-22	complement C1s	Rattus norvegicus	60-71
1363120-3	1992	The urinary excretion of gamma-glutamyltranspeptidase (gamma-GTP) and N-acetyl-beta-D-glucosaminidase (NAG) remained high for at least 3 d after the injection of BSO (100 mg/kg) and DEM (0.5 ml/kg), with no effect on the blood urea nitrogen level.	Nitrogen	232-240	O-GlcNAcase	Rattus norvegicus	70-101
1363120-3	1992	The urinary excretion of gamma-glutamyltranspeptidase (gamma-GTP) and N-acetyl-beta-D-glucosaminidase (NAG) remained high for at least 3 d after the injection of BSO (100 mg/kg) and DEM (0.5 ml/kg), with no effect on the blood urea nitrogen level.	Nitrogen	232-240	O-GlcNAcase	Rattus norvegicus	103-106
20356002-8	2009	N2 adsorption-desorption measurement shows that the CaF2 hollow microspheres possess a high Brunauer-Emmett-Teller surface area and porosity properties.	Nitrogen	0-2	CCR4-NOT transcription complex subunit 8	Homo sapiens	52-56
1504095-6	1992	We demonstrate that removal of N-linked carbohydrate chains increases the sensitivity of 5"-nucleotidase to proteolytic attack, indicating that sugar moieties protect against proteolysis.	Nitrogen	31-32	5'-nucleotidase ecto	Gallus gallus	89-104
2172945-6	1990	These observations indicate that the N-acetylation of beta-endorphin and alpha-MSH occurs at distinct subcellular sites in intermediate pituitary cells of anuran amphibians.	Nitrogen	37-38	proopiomelanocortin L homeolog	Xenopus laevis	73-82
24220807-5	1990	This evidence suggests that the Rj4 allele has a positive value to the host plant in shielding it from nodulation by certain chlorosis-inducing bradyrhizobia of a DNA homology group with impaired efficiency of nitrogen fixation with soybean.	Nitrogen	210-218	thaumatin-like protein 1	Glycine max	32-35
19371318-13	2009	From incubations with HLM and rUGT enzymes, N-glucuronidation of 1"-OH MDZ and 4-OH MDZ is also inferred.	Nitrogen	44-45	UDP-glucose glycoprotein glucosyltransferase 1	Rattus norvegicus	30-34
1322832-0	1992	CDC25-dependent induction of inositol 1,4,5-trisphosphate and diacylglycerol in Saccharomyces cerevisiae by nitrogen.	Nitrogen	108-116	Ras family guanine nucleotide exchange factor CDC25	Saccharomyces cerevisiae S288C	0-5
1357020-1	1992	Tyrosine hydroxylase (TH) protein was measured in the carotid body and adrenal gland of rats exposed to normobaric hypoxia (10% O2 in nitrogen) for 3, 7, 14 or 22 days.	Nitrogen	134-142	tyrosine hydroxylase	Rattus norvegicus	0-20
1357020-1	1992	Tyrosine hydroxylase (TH) protein was measured in the carotid body and adrenal gland of rats exposed to normobaric hypoxia (10% O2 in nitrogen) for 3, 7, 14 or 22 days.	Nitrogen	134-142	tyrosine hydroxylase	Rattus norvegicus	22-24
1352293-0	1992	In vitro mutagenesis of potential N-glycosylation sites of arylsulfatase A.	Nitrogen	34-35	arylsulfatase A	Homo sapiens	59-74
2185888-5	1990	(1988) found that overexpression of IME1 allowed sporulation in the presence of glucose and nitrogen.	Nitrogen	92-100	transcription factor IME1	Saccharomyces cerevisiae S288C	36-40
18952724-7	2009	Immunoblotting using a rabbit polyclonal antibody to UT-B confirmed the presence of distinct 32-kDa (consistent with a nonglycosylated UT-B protein) and 47-kDa (probable N-glycosylated form of UT-B) protein bands in all 9 tissues analyzed.	Nitrogen	170-171	urea transporter 1	Ovis aries	53-57
2332452-5	1990	A surprising incidental result was that when held in the endoplasmic reticulum at low temperature POMC is apparently subject to post-translational N-linked glycosylation.	Nitrogen	147-148	pro-opiomelanocortin-alpha	Mus musculus	98-102
2299062-8	1990	Cox survivorship analyses, using pertinent baseline clinical variables along with nonfatal reinfarction as a time-dependent predictor variable, revealed that nonfatal reinfarction carried a significant and independent risk for subsequent cardiac mortality (hazard ratio 3.0, p = 0.002), which was greater than that carried by other significant predictor variables (New York Heart Association functional class, pulmonary congestion on chest radiograph, blood urea nitrogen level, predischarge Holter-recorded ventricular premature complexes and radionuclide ejection fraction).	Nitrogen	463-471	cytochrome c oxidase subunit 8A	Homo sapiens	0-3
1304375-9	1992	N-deglycosylation of human and rabbit SBP has no effect on the steroid-binding activity, but removal of the O-linked side chains of N-deglycosylated human SBP results in an apparent 50% loss of steroid-binding activity and an increase in the Kd for the binding of 5 alpha-dihydrotestosterone from 0.3 mM to 0.9 nM.	Nitrogen	0-1	sex hormone-binding globulin	Oryctolagus cuniculus	38-41
1444161-2	1992	After 6 months a significant reduction of SBP and DBP (p &lt; 0.001), with improvement of creatinine clearance and with no adverse effects on ECG, heart rate and routine laboratory tests test, was observed in 3 patients treated with N 20 mg x 2/d + E 10 mg/d + A 50 mg/d and in 8 patients treated with N 20 mg x 3 + E 10 mg x 2, + A 50 mg x 2.	Nitrogen	233-234	selenium binding protein 1	Homo sapiens	42-45
1333231-5	1992	At its nonpermissive temperature, a Dol-P-Man synthase mutant (dpm1) was blocked in N-glycosylation, O-mannosylation, and glycosyl phosphoinositol membrane anchoring of protein, most likely because Dol-P-Man serves as mannosyl donor in all three pathways.	Nitrogen	84-85	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	63-67
2303788-2	1990	Altering the N-linked carbohydrates on stimulator cells by use of the N-linked trimming glycosidase inhibitors 1-deoxymannojirimycin and swainsonine, or by treatment with bacterial neuraminidase, results in a restoration of the B6 anti-bm6 response in the absence of CD4+ cells.	Nitrogen	13-14	neuraminidase 1	Homo sapiens	181-194
19153125-6	2009	The monoclonal antibody (mAb) 250448 was specific for the N-()glycosylated form of PRLR and blocked PRL binding and signalling.	Nitrogen	58-59	prolactin receptor	Homo sapiens	83-87
2087924-2	1990	These aspects exemplified by xanthine oxidoreductase from vertebrates of various type of nitrogen excretion are discussed.	Nitrogen	89-97	xanthine dehydrogenase	Homo sapiens	29-52
1386250-8	1992	Results of the investigations reveal that the isothiourea moiety of dimaprit most probably interacts with the histamine H2-receptor through the sulphur and nitrogen atom, the first atom acting as a proton acceptor and the second one as a proton donor.	Nitrogen	156-164	histamine receptor H2	Homo sapiens	110-131
19436134-9	2009	Mutant FGF23 significantly decreased serum creatinine and serum urea nitrogen.	Nitrogen	69-77	fibroblast growth factor 23	Rattus norvegicus	7-12
1532296-0	1992	N-glycosylation plays a role in biosynthesis and internalization of the adenylate cyclase stimulating vasopressin V2-receptor of LLC-PK1 renal epithelial cells: an effect of concanavalin A on binding and expression.	Nitrogen	0-1	vasopressin receptor 2	Sus scrofa	102-125
1532296-1	1992	The role of N-glycosylation in the function and biosynthesis of the vasopressin V2-receptor in LLC-PK1 renal epithelial cells was examined using various lectins and inhibitors operating at different steps of the glycosidic pathway.	Nitrogen	12-13	vasopressin receptor 2	Sus scrofa	68-91
33823663-3	2021	Phosphorylation levels at more than 1000 sites were altered following nitrogen stress or Torin1 inhibition of the TORC1 and TORC2 networks that comprise TOR signalling.	Nitrogen	70-78	CREB regulated transcription coactivator 1	Homo sapiens	114-119
33823663-5	2021	Elimination of AMPK inhibition of TORC1, by removal of AMPKalpha (ssp2::ura4+), identified phosphosites where nitrogen stress-induced changes were independent of TOR control.	Nitrogen	110-118	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	15-19
33823663-5	2021	Elimination of AMPK inhibition of TORC1, by removal of AMPKalpha (ssp2::ura4+), identified phosphosites where nitrogen stress-induced changes were independent of TOR control.	Nitrogen	110-118	CREB regulated transcription coactivator 1	Homo sapiens	34-39
19623990-6	2009	Injected G-CSF 50 ug x kg(-1) x d(-1) in western medicine group subcutaneously, NS 50 g x kg(-1) x d(-1) in sham group and model group.	Nitrogen	80-82	colony stimulating factor 3	Rattus norvegicus	9-14
33801867-8	2021	At phase 3, TRT2 group piglets showed a significant improvement on nutrient digestibility of dry matter (p = 0.012) and nitrogen (p = 0.040).	Nitrogen	120-128	TRT2	Saccharomyces cerevisiae S288C	12-16
1605725-0	1992	Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.	Nitrogen	30-31	arylamine N-acetyltransferase 2	Mesocricetus auratus	169-186
1371336-4	1992	We demonstrate, using both CHO and AtT-20 cells transfected with human Wnt-2 cDNA, that Wnt-2 encodes a 33 kDa protein that is modified by N-linked glycosylation to a 35 kDa species.	Nitrogen	79-80	Wnt family member 2	Homo sapiens	71-76
1371336-4	1992	We demonstrate, using both CHO and AtT-20 cells transfected with human Wnt-2 cDNA, that Wnt-2 encodes a 33 kDa protein that is modified by N-linked glycosylation to a 35 kDa species.	Nitrogen	79-80	Wnt family member 2	Homo sapiens	88-93
19124153-4	2009	We found that nitrogen-doped diamond-like carbon (DLC:N) promoted cell attachment relative to other materials tested in the rank order of DLC:N&gt;In(2)O(3)/SnO(2) (ITO), Pt&gt;Au.	Nitrogen	14-22	strawberry notch homolog 1	Homo sapiens	157-160
1764065-3	1991	Bovine tissue factor had three potential N-glycosylation sites, four extracellular cysteine residues, a cytoplasmic cysteine residue, and one tripeptide tryptophan-lysine-serine motif.	Nitrogen	41-42	LOC101909187	Bos taurus	7-20
33589673-3	2021	Nitrogen fertilisation rates were 50, 150, and 450 kg N ha-1 yr-1 (N50, N150, N450).	Nitrogen	0-8	solute carrier family 9 member B1	Homo sapiens	54-65
19159617-0	2009	Role of E-cadherin N-glycosylation profile in a mammary tumor model.	Nitrogen	19-20	cadherin 1	Canis lupus familiaris	8-18
19159617-2	2009	This study characterizes the N-glycosylation profile of E-cadherin in models of canine mammary gland adenoma and carcinoma evaluating the importance of these glycosylation modifications in the malignant phenotype.	Nitrogen	29-30	cadherin 1	Canis lupus familiaris	56-66
24501762-7	2014	Our study reports the first case of NSXLID caused by a mutation in ALG13 involved in protein N-glycosylation.	Nitrogen	36-37	ALG13 UDP-N-acetylglucosaminyltransferase subunit	Homo sapiens	67-72
1839590-6	1991	These studies describe a new phenomenon, that low doses of nitrogen-containing bisphosphonates can act synergistically with PTH and enhance osteoclastic resorption.	Nitrogen	59-67	parathyroid hormone	Mus musculus	124-127
19159617-3	2009	Our results show that the pattern of E-cadherin N-glycosylation in mammary carcinoma is characterized by highly branched N-glycans, increase in sialylation and an expression of few high mannose structures.	Nitrogen	48-49	cadherin 1	Canis lupus familiaris	37-47
19159617-4	2009	Detailed mass spectrometry analysis demonstrated a new N-glycosylation site containing a potential complex type N-glycan in E-cadherin from a mammary carcinoma cell line.	Nitrogen	55-56	cadherin 1	Canis lupus familiaris	124-134
18704946-6	2009	This binding mode places 5-HT deep in the binding pocket of the SERT with the 5-position near residue hSERT A169/dSERT D164 in transmembrane helix 3, the indole nitrogen next to residue Y176/Y171, and the ethylamine tail under residues F335/F327 and S336/S328 within 4 A of residue D98.	Nitrogen	161-169	Serotonin transporter	Drosophila melanogaster	113-118
1911840-4	1991	N-methylated and non-methylated calmodulins were both cleaved by calmodulin proteinase and while troponin was a poor substrate, it was cleaved in the presence of either calcium or EGTA.	Nitrogen	0-1	calmodulin 1	Rattus norvegicus	32-42
2069595-12	1991	A higher ratio of N-deacetylation and N-acetylation activities, resulting in a higher availability of cysteine S-conjugate, in addition to a higher specific activity of cysteine S-conjugate beta-lyase, probably explains the higher nephrotoxicity of TFE-NAc and CTFE-NAc when compared to DCDFE-NAc and DBDFE-NAc.	Nitrogen	18-19	kynurenine aminotransferase 1	Rattus norvegicus	169-200
2069595-12	1991	A higher ratio of N-deacetylation and N-acetylation activities, resulting in a higher availability of cysteine S-conjugate, in addition to a higher specific activity of cysteine S-conjugate beta-lyase, probably explains the higher nephrotoxicity of TFE-NAc and CTFE-NAc when compared to DCDFE-NAc and DBDFE-NAc.	Nitrogen	38-39	kynurenine aminotransferase 1	Rattus norvegicus	169-200
1862663-14	1991	The concn of 4-acetyl-aminobiphenyl (AABP) plateaued at 17 nmol/ml after 15 min, indicating a dynamic equilibrium between N-acetylation of ABP and N-deacetylation of AABP.	Nitrogen	122-123	sex hormone binding globulin	Rattus norvegicus	38-41
1862663-19	1991	After 4 h the concn of AABP and ABP was 27-35 mmol/ml, indicating a dynamic equilibrium between N-deacetylation of AABP and acetylation of ABP.	Nitrogen	96-97	sex hormone binding globulin	Rattus norvegicus	24-27
34958906-4	2022	With influent concentration of NH4+-N of 909+-101 mg-N/L and COD of 731+-26 mg/L, the nitrogen removal efficiency was 86.8% (nitrogen loading rate of 1.21 g-TN/L/d) and the COD removal efficiency was 50.5% (COD loading rate at 0.98 g-COD/L/d).	Nitrogen	86-94	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	61-64
34958906-4	2022	With influent concentration of NH4+-N of 909+-101 mg-N/L and COD of 731+-26 mg/L, the nitrogen removal efficiency was 86.8% (nitrogen loading rate of 1.21 g-TN/L/d) and the COD removal efficiency was 50.5% (COD loading rate at 0.98 g-COD/L/d).	Nitrogen	125-133	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	61-64
34958906-6	2022	The nitritation and anammox route was predominant in nitrogen removal, while COD oxidation and microbe proliferation played the main role in COD removal.	Nitrogen	53-61	small nuclear ribonucleoprotein polypeptides B and B1	Homo sapiens	77-80
34979278-5	2022	In T, denitrifying genes nirK and nosZ were 11% and 18% lower than those in CK, respectively, while nitrogen-fixing genes nifK and nifD were 18% and 34% higher than those in control group, respectively.	Nitrogen	100-108	nucleolar protein interacting with the FHA domain of MKI67	Homo sapiens	122-126
34655620-6	2022	Total nitrogen (TN) was the most influential factor shaping the biogeographic patterns of both abundant and rare taxa.	Nitrogen	6-14	C-type lectin domain family 3 member B	Homo sapiens	16-18
1702293-6	1990	TNF-BP contains 24 cysteine residues and three potential N-glycosylation sites and shows sequence homology to the extracellular portions of TNF-R p80 chain and nerve growth factor receptor.	Nitrogen	1-2	coilin	Homo sapiens	146-149
19166365-4	2009	The results of density functional theory (DFT) calculations indicate that these results can be rationalized by invoking the existence of an equilibrium of hydrolysis of the Cu-N bond with the amino group supporting the quinoline ring so that CuL1(2+) would be actually a mixture of tbp [CuL1(H(2)O)](2+) and sp [CuL1(H(2)O)(2)](2+).	Nitrogen	176-177	cullin 1	Homo sapiens	242-246
34844319-5	2022	Wet N deposition rates were higher in Yangzhou (developing city, 20.3-22.7 kg N ha-1 yr-1) than those in Nanjing (developed city, 19.4-20.5 kg N ha-1 yr-1), and were higher at urban sites (20.4-22.5 kg N ha-1 yr-1) than those at suburban sites (18.7-20.3 kg N ha-1 yr-1).	Nitrogen	4-5	solute carrier family 9 member B1	Homo sapiens	78-89
34844319-5	2022	Wet N deposition rates were higher in Yangzhou (developing city, 20.3-22.7 kg N ha-1 yr-1) than those in Nanjing (developed city, 19.4-20.5 kg N ha-1 yr-1), and were higher at urban sites (20.4-22.5 kg N ha-1 yr-1) than those at suburban sites (18.7-20.3 kg N ha-1 yr-1).	Nitrogen	4-5	solute carrier family 9 member B1	Homo sapiens	143-154
34844319-5	2022	Wet N deposition rates were higher in Yangzhou (developing city, 20.3-22.7 kg N ha-1 yr-1) than those in Nanjing (developed city, 19.4-20.5 kg N ha-1 yr-1), and were higher at urban sites (20.4-22.5 kg N ha-1 yr-1) than those at suburban sites (18.7-20.3 kg N ha-1 yr-1).	Nitrogen	4-5	solute carrier family 9 member B1	Homo sapiens	202-213
19166365-4	2009	The results of density functional theory (DFT) calculations indicate that these results can be rationalized by invoking the existence of an equilibrium of hydrolysis of the Cu-N bond with the amino group supporting the quinoline ring so that CuL1(2+) would be actually a mixture of tbp [CuL1(H(2)O)](2+) and sp [CuL1(H(2)O)(2)](2+).	Nitrogen	176-177	cullin 1	Homo sapiens	287-291
19166365-4	2009	The results of density functional theory (DFT) calculations indicate that these results can be rationalized by invoking the existence of an equilibrium of hydrolysis of the Cu-N bond with the amino group supporting the quinoline ring so that CuL1(2+) would be actually a mixture of tbp [CuL1(H(2)O)](2+) and sp [CuL1(H(2)O)(2)](2+).	Nitrogen	176-177	cullin 1	Homo sapiens	287-291
34846075-0	2022	Missing Member in the MIIMIIISi4N7 Compound Class: Carbothermal Reduction and Nitridation Synthesis Revealing Substitution of N by C and O in CaLu(Si4N7-2xCxOx):Eu2+/Ce3+ (x   0.3).	Nitrogen	126-127	calumenin	Homo sapiens	142-146
19194162-10	2009	Pretreatment with capsazepine, CGRP(8-37), indomethacin, and denervation of primary sensory nerves significantly increased blood urea nitrogen and serum creatinine levels, renal vascular permeability, renal tissue levels of myeloperoxidase activity, cytokine-induced neutrophil chemoattractant, and tumor necrosis factor-alpha, and decreased renal tissue blood flow.	Nitrogen	134-142	calcitonin-related polypeptide alpha	Rattus norvegicus	31-35
34507168-2	2022	In this study, excellent photoexcited charge carrier separation and enhanced visible-light response were achieved with nitrogen-doped titania nanobelts (N-TNBs), whose 1D geometry facilitated the fabrication of a heterostructure with SnS2 on the surface of graphitic carbon nitride (g-C3N4).	Nitrogen	119-127	sodium voltage-gated channel alpha subunit 11	Homo sapiens	234-238
34507168-4	2022	UV-vis diffuse reflectance spectroscopy analysis revealed a red shift in the absorption spectra of the SnS2@N-TNB and SnS2@N-TNB/g-C3N4 samples.	Nitrogen	123-124	sodium voltage-gated channel alpha subunit 11	Homo sapiens	118-122
19134474-4	2009	FTIR spectroscopy of fully (13)C,(15)N-labeled MBP complexed with unlabeled F-actin showed induced folding of both protein partners, viz., some increase in beta-sheet content in actin, and increases in both alpha-helix and beta-sheet content in MBP, albeit with considerable extended structure remaining.	Nitrogen	37-38	myelin basic protein	Homo sapiens	47-50
34928569-2	2022	In this study, the computation-ready experimental (CoRE) metal-organic framework (MOF) data set for which the O2 and N2 uptakes, self-diffusivities, and Henry"s constants were calculated was used to fit the ML models.	Nitrogen	117-119	lysine acetyltransferase 8	Homo sapiens	82-85
34928569-3	2022	The obtained models were subsequently employed to predict such properties for a hypothetical MOF (hMOF) data set and to identify structures having a high O2/N2 selectivity at room temperature.	Nitrogen	157-159	lysine acetyltransferase 8	Homo sapiens	93-96
34928569-3	2022	The obtained models were subsequently employed to predict such properties for a hypothetical MOF (hMOF) data set and to identify structures having a high O2/N2 selectivity at room temperature.	Nitrogen	157-159	lysine acetyltransferase 8	Homo sapiens	98-102
34894661-7	2021	Extensive experimental work and DFT calculations regarded that due to the charge redistribution, the Mott-Schottky effect, and the band bending of SnS2 across the contact layer at the interface of NPG, the d-band center for the surface Sn atoms in NPG@SnS2 lowered, which resulted in favored adsorption of N2 on the Sn active site.	Nitrogen	306-308	sodium voltage-gated channel alpha subunit 11	Homo sapiens	147-151
34894661-7	2021	Extensive experimental work and DFT calculations regarded that due to the charge redistribution, the Mott-Schottky effect, and the band bending of SnS2 across the contact layer at the interface of NPG, the d-band center for the surface Sn atoms in NPG@SnS2 lowered, which resulted in favored adsorption of N2 on the Sn active site.	Nitrogen	306-308	sodium voltage-gated channel alpha subunit 11	Homo sapiens	252-256
19134474-4	2009	FTIR spectroscopy of fully (13)C,(15)N-labeled MBP complexed with unlabeled F-actin showed induced folding of both protein partners, viz., some increase in beta-sheet content in actin, and increases in both alpha-helix and beta-sheet content in MBP, albeit with considerable extended structure remaining.	Nitrogen	37-38	myelin basic protein	Homo sapiens	245-248
19356114-0	2009	Structure-activity relationship (SAR): effort towards blocking N-glucuronidation of indazoles (PF-03376056) by human UGT1A enzymes.	Nitrogen	63-64	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	117-122
34939741-2	2022	Lower solubility and leaching study showed the newly synthesized urea   adipic acid 2 : 1 cocrystal to be an efficient sustained-release nitrogen fertilizer compared to commercially available urea.	Nitrogen	137-145	PTOV1 extended AT-hook containing adaptor protein	Homo sapiens	79-85
34774484-0	2021	N-glycosylation status of Trop2 impacts its surface density, interaction with claudin-7 and exosomal release.	Nitrogen	0-1	claudin 7	Homo sapiens	78-87
18637708-1	2009	Nitrogen-containing bisphosphonates were found to inhibit farnesyl diphosphate synthase - an essential enzyme in the cholesterol biosynthesis pathway, but their effect on cholesterol synthesis per se in the central nervous system (CNS) remains unknown.	Nitrogen	0-8	farnesyl diphosphate synthase	Rattus norvegicus	58-87
34904377-0	2021	Critical role for uricase and xanthine dehydrogenase in soybean nitrogen fixation and nodule development.	Nitrogen	64-72	uricase-2 isozyme 1	Glycine max	18-25
34904377-5	2021	Using a forward genetic approach, as well as CRISPR/Cas9 gene editing via Agrobacterium rhizogenes-mediated hairy root transformation, we identified and characterized the role of GmUOX (Uricase) and GmXDH (Xanthine Dehydrogenase) in nitrogen fixation and nodule development in soybean.	Nitrogen	233-241	uricase-2 isozyme 1	Glycine max	186-193
19073648-5	2009	Concentration-dependent analysis of (15)N-labeled ammonium influx into roots of AtAMT1;4-transformed plants allowed characterization of AtAMT1;4 as a high-affinity transporter with a K(m) of 17 microM.	Nitrogen	40-41	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	80-86
34876606-0	2021	N-glycosylation profiles of the SARS-CoV-2 spike D614G mutant and its ancestral protein characterized by advanced mass spectrometry.	Nitrogen	0-1	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	43-48
34876606-4	2021	In this report, we used mass spectrometry techniques to characterize and compare the N-glycosylation of the wild type (S-614D) or variant (S-614G) SARS-CoV-2 spike glycoproteins prepared under identical conditions.	Nitrogen	85-86	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	158-163
34024253-0	2021	Parathyroid hormone-related protein inhibits nitrogen-containing bisphosphonate-induced apoptosis of human periodontal ligament fibroblasts by activating MKP1 phosphatase.	Nitrogen	45-53	parathyroid hormone like hormone	Homo sapiens	0-35
34024253-4	2021	Therefore, it is speculated that PTHrP can inhibit the apoptosis of HPdLFs caused by nitrogen-containing BP via regulating the expression levels of MKP1.	Nitrogen	85-93	parathyroid hormone like hormone	Homo sapiens	33-38
18563875-6	2008	The calculations show that azole binding is a stepwise mechanism whereby first the water molecule from the resting state of P450 is released from the sixth binding site of the heme to create a pentacoordinated active site followed by coordination of the azole nitrogen to the heme iron.	Nitrogen	260-268	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	124-128
34614557-5	2021	Complete removal of 1.8 to 2614 mg/L of nitrogen heterocyclic PAH (PANH), 0.27 to 184 mg/L of sulfur heterocyclic PAH (PASH), and 0.6 to 120 mg/L of oxygen heterocyclic PAH (PAOH) compounds by various microbial species was observed between 3 h and 18 days, 8 h to 6 days, and 4 h to 250 h, respectively under aerobic condition.	Nitrogen	40-48	spermine oxidase	Homo sapiens	62-65
34319422-1	2021	The yeast prions (infectious proteins) (URE3) and (PSI+) are essentially non-functional (or even toxic) amyloid forms of Ure2p and Sup35p, whose normal function is in nitrogen catabolite repression and translation termination, respectively.	Nitrogen	167-175	translation termination factor GTPase eRF3	Saccharomyces cerevisiae S288C	131-137
18955570-5	2008	The other, a point mutation in the paternal X chromosome allele encoding a G174R substitution, altered an N-linked glycosylation site within the cytokine binding domain and glycosylation of GM-CSF-Ralpha, severely reducing GM-CSF binding, receptor signaling, and GM-CSF-dependent functions in primary myeloid cells.	Nitrogen	106-107	colony stimulating factor 2 receptor subunit alpha	Homo sapiens	190-203
34510656-3	2021	Using a global meta-analysis based on 901 observations from 330 15 N-labelled studies, we show that GN differs significantly among ecosystem types, with the highest rates found in croplands, in association with higher pH which stimulates nitrifying bacteria activities.	Nitrogen	67-68	phenylalanine hydroxylase	Homo sapiens	218-220
18160179-5	2008	Analyses of the steady-state mRNA levels of SAN1A and SAN1B during senescence induced by treatment with fixed nitrogen or darkness demonstrate that SAN1A is downregulated during induced senescence.	Nitrogen	110-118	senescence-associated nodulin 1A	Glycine max	44-49
34837246-2	2022	In this study, under N- and P-free nutrient solution (-N-P), nodulating white lupin plants developed some nodules and analogous cluster root structures characterized by different morphological, physiological, and molecular responses than those observed upon single nutrient deficiency (strong acidification of external media, a better nutritional status than -N+P and +N-P plants).	Nitrogen	21-22	5'-nucleotidase, cytosolic IIIA	Homo sapiens	78-83
34837246-2	2022	In this study, under N- and P-free nutrient solution (-N-P), nodulating white lupin plants developed some nodules and analogous cluster root structures characterized by different morphological, physiological, and molecular responses than those observed upon single nutrient deficiency (strong acidification of external media, a better nutritional status than -N+P and +N-P plants).	Nitrogen	55-56	5'-nucleotidase, cytosolic IIIA	Homo sapiens	78-83
18160179-5	2008	Analyses of the steady-state mRNA levels of SAN1A and SAN1B during senescence induced by treatment with fixed nitrogen or darkness demonstrate that SAN1A is downregulated during induced senescence.	Nitrogen	110-118	senescence-associated nodulin 1B	Glycine max	54-59
18160179-5	2008	Analyses of the steady-state mRNA levels of SAN1A and SAN1B during senescence induced by treatment with fixed nitrogen or darkness demonstrate that SAN1A is downregulated during induced senescence.	Nitrogen	110-118	senescence-associated nodulin 1A	Glycine max	148-153
34824205-1	2021	The visible light induced, photocatalysts or photoabsorbing EDA complexes mediated cleavage of pyridinium C-N bond were reported in the past years.	Nitrogen	108-109	ectodysplasin A	Homo sapiens	60-63
34661088-0	2021	The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor.	Nitrogen	14-15	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	44-49
18523964-3	2008	Only pentapeptides, containing free N-termini appeared to act as weak inhibitors of cathepsin C with the slow-binding, competitive mechanism of inhibition, free acids being bound slightly better than their methyl esters.	Nitrogen	36-37	cathepsin C	Homo sapiens	84-95
34661088-0	2021	The effect of N-glycosylation of SARS-CoV-2 spike protein on the virus interaction with the host cell ACE2 receptor.	Nitrogen	14-15	angiotensin converting enzyme 2	Homo sapiens	102-106
34873473-2	2021	In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (MET) and epidermal growth factor receptor (EGFR).	Nitrogen	110-111	fucosyltransferase 8	Homo sapiens	32-52
34873473-2	2021	In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (MET) and epidermal growth factor receptor (EGFR).	Nitrogen	110-111	fucosyltransferase 8	Homo sapiens	54-58
18753286-8	2008	Furthermore, overexpression of AtPTR5 resulted in enhanced shoot growth and increased N content.	Nitrogen	86-87	peptide transporter 5	Arabidopsis thaliana	31-37
34827886-3	2021	The alien species occurrences correlated positively (p < 0.05) with poor water quality, such as rivers with high ammonia-nitrogen and nitrite, but negatively with phosphate and dissolved oxygen.	Nitrogen	121-129	COP9 signalosome subunit 2	Homo sapiens	4-9
34827886-5	2021	In general, the results of fish stomach contents analyses and their associated indices, together with stable carbon and nitrogen isotopes, revealed domination by alien fishes or diet overlaps between both alien and native fish species.	Nitrogen	120-128	COP9 signalosome subunit 2	Homo sapiens	162-167
34827886-5	2021	In general, the results of fish stomach contents analyses and their associated indices, together with stable carbon and nitrogen isotopes, revealed domination by alien fishes or diet overlaps between both alien and native fish species.	Nitrogen	120-128	COP9 signalosome subunit 2	Homo sapiens	205-210
18692125-5	2008	Increase of aspartate transanimase (AST), alanine transaminase (ALT), urea nitrogen (BUN), and creatinine in the serum of CTX-treated mice was significantly reversed by ATF.	Nitrogen	75-83	glial cell line derived neurotrophic factor	Mus musculus	169-172
34585194-7	2021	CYP also increased the content of ATP in musculus gastrocnemius, which was down-regulated by DDP; the DDP had significantly enhanced the contents of interleukin-1beta (IL-lbeta), malondialdehyde (MDA), blood urea nitrogen (BUN) and lactic dehydrogenase (LDH) and inhibited the activity of superoxide dismutase (SOD) in the muscle.	Nitrogen	213-221	peptidyl-prolyl isomerase G (cyclophilin G)	Mus musculus	0-3
18722778-2	2008	The tetrahydropyridine 6 is a novel TRPV1 receptor antagonist that potently inhibits receptor-mediated Ca2+ influx in vitro induced by several agonists, including capsaicin, N-arachidonoyldopamine (NADA), and low pH.	Nitrogen	174-175	transient receptor potential cation channel subfamily V member 1	Homo sapiens	36-41
34285372-2	2021	Activation of the nociceptin opioid peptide (NOP) receptor by its endogenous ligand Nociceptin/Orphanin FQ (N/OFQ) attenuates alcohol drinking and relapse in rodents, suggesting that NOP agonists may be efficacious in treating AUD.	Nitrogen	108-109	opioid related nociceptin receptor 1	Homo sapiens	45-48
34718979-5	2022	Moreover, the addition of human manure increased the proportions of Nr footprint by 6.6% (CHF1) and 2.9% (CHF2) in comparison with CF treatment.	Nitrogen	68-70	hes related family bHLH transcription factor with YRPW motif 2	Homo sapiens	90-94
18619416-2	2008	Both these transporters contain potential sites for N-glycosylation in their extracellular domains (Asn-138, Asn-144 [hSVCT1]; Asn-188, Asn-196 [hSVCT2]), however the role of N-glycosylation in transporter function is unexplored.	Nitrogen	52-53	solute carrier family 23 member 2	Homo sapiens	145-151
34643369-5	2021	RH-EDA itself is almost nonfluorescent in physiological conditions, which was attributed to the formation of a twisted intramolecular charge transfer (TICT) state upon photoexcitation and the acylation of its rhodamine nitrogen at the 3" position.	Nitrogen	219-227	ectodysplasin A	Homo sapiens	3-6
18619416-4	2008	We show that removal of individual N-glycosylation sites significantly impairs protein expression and consequently ascorbic acid uptake for hSVCT1 mutants (N138Q is retained intracellularly) and for hSVCT2 mutants (all of which reach the cell surface).	Nitrogen	35-36	solute carrier family 23 member 2	Homo sapiens	199-205
18656202-5	2008	In addition, the results of (13)C CP/MAS NMR demonstrated that the N-alkyl moieties of the grafted polymers chain in Sil-T1 remained disordered, amorphous, and mobile represented by gauche conformational form.	Nitrogen	41-42	STIL centriolar assembly protein	Homo sapiens	117-120
34675266-8	2021	Second, compared with TP, EP can improve bulk density (BD), soil organic carbon (SOC), total nitrogen (TN) and cation exchange capacity (CEC), Finally, the chemical weathering intensity differed among NE, TP and EP and followed the order of TP > NE > EP.	Nitrogen	93-101	epiregulin	Homo sapiens	26-28
34675266-8	2021	Second, compared with TP, EP can improve bulk density (BD), soil organic carbon (SOC), total nitrogen (TN) and cation exchange capacity (CEC), Finally, the chemical weathering intensity differed among NE, TP and EP and followed the order of TP > NE > EP.	Nitrogen	93-101	epiregulin	Homo sapiens	212-214
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	356-364	group 3 secretory phospholipase A2	Ovis aries	257-263
18690846-3	2008	Immunoblots of whole cell lysates, subcellular fractionation and tunicamycin treatment of human tumor cells indicated that 4Ig-hB7H3 is a approximately 100-kDa N-linked glycosylated membrane protein.	Nitrogen	160-161	CD276 molecule	Homo sapiens	123-132
34127537-5	2021	To date, limited detail is known about IgA O- and N-glycosylation in IgAN.	Nitrogen	50-51	IGAN1	Homo sapiens	69-73
34127537-6	2021	Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls.	Nitrogen	50-51	IGAN1	Homo sapiens	92-96
34127537-7	2021	Results: Multiple structural features of N-glycosylation of IgA1 and IgA2 were associated with IgAN and glomerular function in our cross-sectional study.	Nitrogen	41-42	IGAN1	Homo sapiens	95-99
18646010-6	2008	siRNA targeting LGALS3, WBSCR17, PHF3, SDC2 and CTNNAL1 partially reversed the GlcNAc-induced phenotypes, suggesting a role for galectin-3/N-glycans, proteoglycans, O-glycans, and junctional cell adhesion.	Nitrogen	3-4	galectin 3	Homo sapiens	16-22
34218916-1	2021	Limited research with growing ruminants indicates that oscillating (OS) dietary crude protein (CP) concentration may improve nitrogen use efficiency (NUE).	Nitrogen	125-133	ceruloplasmin	Bos taurus	95-97
34646995-0	2021	Site-specific N-glycosylation of integrin alpha2 mediates collagen-dependent cell survival.	Nitrogen	14-15	integrin subunit alpha 2	Homo sapiens	33-48
34557012-6	2021	In vivo, collagen-induced arthritis (CIA) mouse model and EL4 tumor-bearing mouse model were used to characterize the potential roles of N(IL-23+IL-18) in inflammation and tumor.	Nitrogen	137-138	interleukin 23, alpha subunit p19	Mus musculus	139-144
34557012-6	2021	In vivo, collagen-induced arthritis (CIA) mouse model and EL4 tumor-bearing mouse model were used to characterize the potential roles of N(IL-23+IL-18) in inflammation and tumor.	Nitrogen	137-138	interleukin 18	Mus musculus	145-150
18646010-6	2008	siRNA targeting LGALS3, WBSCR17, PHF3, SDC2 and CTNNAL1 partially reversed the GlcNAc-induced phenotypes, suggesting a role for galectin-3/N-glycans, proteoglycans, O-glycans, and junctional cell adhesion.	Nitrogen	3-4	galectin 3	Homo sapiens	128-138
18358456-0	2008	Synthesis of 2-amido, 2-amino, and 2-azido derivatives of the nitrogen analogue of the naturally occurring glycosidase inhibitor salacinol and their inhibitory activities against O-GlcNAcase and NagZ enzymes.	Nitrogen	62-70	O-GlcNAcase	Homo sapiens	179-190
34399419-2	2021	We investigate the role of the main air constituents nitrogen, oxygen and water on the efficiency of radiative recombination in GaN nanostructures as a function of different surface treatments and at temperatures up to 200 C. Oxygen and water exposures exhibit a complex behavior as they can both act quenching and enhancing on the photoluminescence intensity dependent on the temperature.	Nitrogen	53-61	gigaxonin	Homo sapiens	128-131
2076815-5	1990	Mutant kem 1 strains are hypersensitive to benomyl, lose chromosomes at a rate 10-20-fold higher than KEM+ strains, and lose viability upon nitrogen starvation.	Nitrogen	140-148	chromatin-binding exonuclease XRN1	Saccharomyces cerevisiae S288C	7-12
18607003-4	2008	In the mammalian OST complex one such subunit, ribophorin I, is proposed to facilitate the N-glycosylation of certain precursors during their biogenesis at the endoplasmic reticulum.	Nitrogen	91-92	ribophorin I	Homo sapiens	47-59
2372889-6	1990	Isosmolar CaCl2 solution infused into the same brachial artery at a rate of 0.09 meq/min severely blunted the vasodilating actions of Mg2+ (-30.1 +/- 6.5% versus -65.8 +/- 3.2%, p less than 0.01, during the infusion of 0.2 meq Mg2+/min) but did not affect those of K+ (-63.1 +/- 3.1% versus -55.9 +/- 3.8%, NS, during the infusion of 0.154 meq K+/min).	Nitrogen	307-309	mucin 7, secreted	Homo sapiens	134-137
34612402-5	2021	We also observed a dip in the transmission spectrum of the biased beta12-BNR along the armchair direction which shows a metal-to-n-doped semiconductor phase transition in the device when applying a strong enough electric field.	Nitrogen	129-130	immunoglobulin kappa variable 2D-19 (pseudogene)	Homo sapiens	66-72
18607003-5	2008	Here, we use cell culture models to show that ribophorin I depletion results in substrate-specific defects in N-glycosylation, clearly establishing a defined physiological role for ribophorin I.	Nitrogen	110-111	ribophorin I	Homo sapiens	46-58
34246830-6	2021	Our results suggest that binding of N to 14-3-3gamma is beneficial for the virus, thus targeting this viral-host protein-protein interaction seems an attractive approach to explore antiviral strategies.	Nitrogen	36-37	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma	Homo sapiens	41-52
2402871-4	1990	Several properties of this polyprotein, like hydrophobicity, position of putative protease cleavage sites, distribution of N-linked glycosylation sites, distribution of cysteines and distribution of acidic and basic residues are described and discussed.	Nitrogen	123-124	polyprotein	Classical swine fever virus	27-38
18607003-6	2008	To address the molecular mechanism of ribophorin I function, a cross-linking approach was used to explore the environment of nascent glycoproteins during the N-glycosylation reaction.	Nitrogen	158-159	ribophorin I	Homo sapiens	38-50
18484961-7	2008	Furthermore, LCA inhibited the cisplatin-induced kidney damage characterized by increases in the serum creatinine and blood urea nitrogen, as well as the cisplatin-induced liver damage characterized by increases in the serum alanine aminotransferase and aspartate aminotransferase.	Nitrogen	129-137	clathrin, light polypeptide (Lca)	Mus musculus	13-16
34504143-0	2021	Smart-cut-like laser slicing of GaN substrate using its own nitrogen.	Nitrogen	60-68	gigaxonin	Homo sapiens	32-35
18418832-2	2008	The dipeptide mimetic, which respectively displayed the side chains of tryptophan and lysine at the nitrogen and O6 atoms of the iminosugar scaffold is a ligand (K(i)=3.2 microM) for the human somatostatin receptor subtype 4 (hSSTR4) but has lower affinity (K(i)&gt;100 microM) for hSSTR5.	Nitrogen	100-108	somatostatin receptor 5	Homo sapiens	282-288
34415013-8	2021	Characterization of pathways that involve AAL and Acp may lead to developing new plant and human disease-controlling agents as well as strains with improved nitrogen fixation capacity.	Nitrogen	157-165	NADH:ubiquinone oxidoreductase subunit AB1	Homo sapiens	50-53
1689645-0	1990	P300 latency indexes nitrogen narcosis.	Nitrogen	21-29	E1A binding protein p300	Homo sapiens	0-4
1689645-6	1990	These results indicate that P300 latency indexes nitrogen narcosis and are interpreted as support for the slowed processing model of inert gas narcosis.	Nitrogen	49-57	E1A binding protein p300	Homo sapiens	28-32
18434410-3	2008	To produce proteins with exclusively high-mannose carbohydrates, we generated a mutant strain of Saccharomyces cerevisiae by deleting three genes in the N-glycosylation pathway, Och1, Mnn1, and Mnn4.	Nitrogen	153-154	Mnn4p	Saccharomyces cerevisiae S288C	194-198
2137690-11	1990	26 per 100 disaccharide units) were distributed almost evenly among C-6 of N-acetylglucosamine, C-2 of iduronate and C-6 of N-sulphated glucosamine residues.	Nitrogen	75-76	complement C6	Homo sapiens	68-71
1968003-6	1990	Both AS1 and AS2 mRNAs also accumulate to high levels in cotyledons of germinating seedlings and in nitrogen-fixing root nodules.	Nitrogen	100-108	prostaglandin D2 receptor	Homo sapiens	5-8
34436666-4	2022	In this review, we summarize existing literature data on PTMs of hCA IX and hCA XII, such as disulphide bond formation, phosphorylation, O-/N-linked glycosylation, acetylation and ubiquitination, highlighting, when possible, their specific role in cancer pathological processes.	Nitrogen	140-141	carbonic anhydrase 9	Homo sapiens	65-71
34512567-3	2021	Here, we aimed to investigate the soil fungal community variations and assembly processes under short- (2 years) versus long-term (13 years) exogenous N addition (~100 kg N ha-1 yr-1) in a N-rich tropical forest of China.	Nitrogen	151-152	solute carrier family 9 member B1	Homo sapiens	171-182
34512567-3	2021	Here, we aimed to investigate the soil fungal community variations and assembly processes under short- (2 years) versus long-term (13 years) exogenous N addition (~100 kg N ha-1 yr-1) in a N-rich tropical forest of China.	Nitrogen	189-190	solute carrier family 9 member B1	Homo sapiens	171-182
18450755-6	2008	In animals fed an n-3 polyunsaturated fatty acid-enriched diet, syndecan 1 mRNA was increased in all prostate glands.	Nitrogen	1-2	syndecan 1	Homo sapiens	64-74
34445285-9	2021	The molecular modeling of GluA1 as one of the good cell surface substrates for GnT-III in the brain, indicated that GnT-III acts on N-glycosylation sites located in a highly flexible and mobile loop of GluA1.	Nitrogen	132-133	glutamate receptor, ionotropic, AMPA1 (alpha 1)	Mus musculus	26-31
34445285-9	2021	The molecular modeling of GluA1 as one of the good cell surface substrates for GnT-III in the brain, indicated that GnT-III acts on N-glycosylation sites located in a highly flexible and mobile loop of GluA1.	Nitrogen	132-133	glutamate receptor, ionotropic, AMPA1 (alpha 1)	Mus musculus	202-207
34309263-1	2021	Currently, the aquatic environment of the Tuojiang River basin in Sichuan Province is severely polluted by non-point sources of total nitrogen (TN).	Nitrogen	134-142	C-type lectin domain family 3 member B	Homo sapiens	144-146
34440751-0	2021	Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer"s Disease.	Nitrogen	31-39	neurotrophic receptor tyrosine kinase 1	Homo sapiens	51-55
2104843-19	1990	There are 11 potential N-glycosylation sites on each thermopsin molecule.	Nitrogen	23-24	ATZ20_RS00970	Sulfolobus acidocaldarius	53-63
2137335-6	1990	The N-terminal sequence of human renal dipeptidase showed a high degree of similarity with that of the pig enzyme, and enzymic deglycosylation revealed that the difference in size of renal dipeptidase between these two species is due almost entirely to differences in the extent of N-linked glycosylation.	Nitrogen	4-5	dipeptidase 1	Homo sapiens	33-50
18691028-0	2008	Levels of N-linked glycosylation on the V1 loop of HIV-1 Env proteins and their relationship to the antigenicity of Env from primary viral isolates.	Nitrogen	10-11	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	57-60
2153019-5	1990	In comparison with controls, rats given corticosterone (75 mg subcutaneously) or TNF (2 x 10(5) U/kg per 24 hours) demonstrated decreased nitrogen balance and diminished carcass nitrogen content over a 6-day period.	Nitrogen	138-146	tumor necrosis factor-like	Rattus norvegicus	81-84
2153019-5	1990	In comparison with controls, rats given corticosterone (75 mg subcutaneously) or TNF (2 x 10(5) U/kg per 24 hours) demonstrated decreased nitrogen balance and diminished carcass nitrogen content over a 6-day period.	Nitrogen	178-186	tumor necrosis factor-like	Rattus norvegicus	81-84
2153019-6	1990	Tumor necrosis factor alone, however, induced a significant increase in liver nitrogen content and diminished jejunal mucosa DNA and protein levels in comparison with the control and corticosterone groups.	Nitrogen	78-86	tumor necrosis factor-like	Rattus norvegicus	0-21
2153019-8	1990	Urinary nitrogen loss was significantly diminished in these animals compared with sham adrenalectomized controls, indicating that an intact adrenal stress response is necessary for the increased nitrogen loss following TNF infusion.	Nitrogen	195-203	tumor necrosis factor-like	Rattus norvegicus	219-222
33802113-10	2021	Urinary N excretion was increased with increased levels of CP, but chitosan inclusion increased the quantity of N excreted in the faeces.	Nitrogen	8-9	ceruloplasmin	Bos taurus	59-61
34444013-4	2021	Regression analysis showed that the algal growth was more highly regulated by total phosphorus (TP; R2 = 0.37) than total nitrogen (TN, R2 = 0.25) and TN/TP (R2 = 0.01) ratios in the river after weir construction and indicated that the river is a P-limited system.	Nitrogen	122-130	C-type lectin domain family 3 member B	Homo sapiens	132-134
34089296-9	2021	Therefore, we proposed that the ESCRT-III machinery mediates nitrogen starvation-induced macromitophagy by the interaction between Snf7 and Atg11 so that Snf7 is recruited to Atg32 marked MPs by the known Atg11-Atg32 interaction to seal them.	Nitrogen	61-69	autophagy protein ATG11	Saccharomyces cerevisiae S288C	140-145
34089296-9	2021	Therefore, we proposed that the ESCRT-III machinery mediates nitrogen starvation-induced macromitophagy by the interaction between Snf7 and Atg11 so that Snf7 is recruited to Atg32 marked MPs by the known Atg11-Atg32 interaction to seal them.	Nitrogen	61-69	ESCRT-III subunit protein SNF7	Saccharomyces cerevisiae S288C	154-158
34212682-4	2021	The results show that:(1) the average annual application intensity of nitrogen and phosphorus fertilizer in the study area from 2010 to 2015 is generally in the low and medium risk intensity of 120-360 kg hm-2 and 60-180 kg hm-2.	Nitrogen	70-78	cholinergic receptor muscarinic 2	Homo sapiens	205-209
34212682-4	2021	The results show that:(1) the average annual application intensity of nitrogen and phosphorus fertilizer in the study area from 2010 to 2015 is generally in the low and medium risk intensity of 120-360 kg hm-2 and 60-180 kg hm-2.	Nitrogen	70-78	cholinergic receptor muscarinic 2	Homo sapiens	224-228
18483264-5	2008	Using the N-linked glycosylation inhibitor, tunicamycin, we show that expression levels of several RTKS (EGFR, ErbB2, ErbB3, and IGF-IR) are exquisitely sensitive to inhibition of N-linked glycosylation.	Nitrogen	10-11	erb-b2 receptor tyrosine kinase 3	Homo sapiens	118-123
34207447-6	2021	Thus, the objective of this study was to analyse the gene and protein expression of the enzymes NOX-1, NOX-2 and iNOS, which are involved in the production of reactive oxygen and nitrogen species, respectively.	Nitrogen	179-187	NADPH oxidase 1	Homo sapiens	96-101
32794734-2	2020	2,6-Bis(5,6-dipropyl-1,2,4-triazin-3-yl)pyridine (nPr-BTP), a tridentate nitrogen donor ligand, is known to form ninefold coordinated 1:3 complexes, [An(nPr-BTP)3]3+ (An = U, Pu, Am, Cm) in solution.	Nitrogen	73-81	neuronal pentraxin receptor	Homo sapiens	50-53
32794734-2	2020	2,6-Bis(5,6-dipropyl-1,2,4-triazin-3-yl)pyridine (nPr-BTP), a tridentate nitrogen donor ligand, is known to form ninefold coordinated 1:3 complexes, [An(nPr-BTP)3]3+ (An = U, Pu, Am, Cm) in solution.	Nitrogen	73-81	neuronal pentraxin receptor	Homo sapiens	153-156
18256203-8	2008	Among the recombinant human UDP glucuronosyltransferase (UGT) isoforms tested, only isoform UGT1A4 catalyzed the N-glucuronidation of MDZ fitting a Michaelis-Menten model.	Nitrogen	113-114	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	28-55
15558123-0	2004	Reaction of [M(eta3-allyl)(eta2-amidinato)(CO)2(pyridine)] complexes (M = Mo, W) with bidentate ligands: nitrogen donor vs. phosphorus donor.	Nitrogen	105-113	DNA polymerase iota	Homo sapiens	27-31
34069925-5	2021	In addition, NH2- produced via the auto coupling ionization of NH3 has strong nucleophilic ability, and is able to fill nitrogen vacancies near the GaN surface created by high temperature process.	Nitrogen	120-128	gigaxonin	Homo sapiens	148-151
18256203-8	2008	Among the recombinant human UDP glucuronosyltransferase (UGT) isoforms tested, only isoform UGT1A4 catalyzed the N-glucuronidation of MDZ fitting a Michaelis-Menten model.	Nitrogen	113-114	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	57-60
18190944-6	2008	It was discovered that the M2L protein possesses motifs characteristic of ER-localized proteins: an N-terminal signal peptide sequence, C-terminal endoplasmic reticulum (ER) retention and retrieval sequences, and N-linked glycosylation sites.	Nitrogen	100-101	hypothetical protein	Vaccinia virus	27-30
34927885-4	2021	Herein, a facile way of preparing bimetallic Fe and Co sites entrapped in nitrogen-doped hollow carbon nanospheres (Fe,Co-SA/CS) is explored, drawing on the unique structure and pore characteristics of Zeolitic imidazole frameworks and molecular size of Ferrocene, an Fe containing species.	Nitrogen	74-82	citrate synthase	Homo sapiens	125-127
34420976-1	2021	BACKGROUND: An N-terminal octapeptide cleavage of the cystatin C protein was discovered by mass spectrometry when cerebrospinal fluid (CSF) was stored at -20 C for 3 months, which did not occur when CSF was stored at -80 C. OBJECTIVE: The aim was to develop an immunoassay as quality assessment tool to detect this -20 C cleavage of cystatin C in CSF and support Alzheimer"s disease research.	Nitrogen	15-16	cystatin C	Homo sapiens	54-64
35421467-4	2022	The results showed that the concentration of NO3--N, NH4+-N, NO2--N and total nitrogen (TN) had vary spatial and temporal changes in whole watershed.	Nitrogen	78-86	C-type lectin domain family 3 member B	Homo sapiens	88-90
35398746-0	2022	Cascade reaction biosensor based on Cu/N co-doped two-dimensional carbon-based nanozyme for the detection of lactose and beta-galactosidase.	Nitrogen	39-40	galactosidase beta 1	Homo sapiens	121-139
34933265-3	2022	Therefore, three single-substrate (gravel, zeolite, and oyster shell) CWs were constructed with the goal of enhancing total nitrogen (TN) removal by anammox-driven/dominant process and determining the effect of substrate on anammox process.	Nitrogen	124-132	C-type lectin domain family 3 member B	Homo sapiens	134-136
34968880-2	2022	In this study, we proposed a real-time measurement method for total nitrogen (TN) by combining the timeliness of sensor detection and the accuracy of intelligent algorithms, based on the physical and chemical relationships between TN and sensor-measured indexes.	Nitrogen	68-76	C-type lectin domain family 3 member B	Homo sapiens	78-80
34968880-2	2022	In this study, we proposed a real-time measurement method for total nitrogen (TN) by combining the timeliness of sensor detection and the accuracy of intelligent algorithms, based on the physical and chemical relationships between TN and sensor-measured indexes.	Nitrogen	68-76	C-type lectin domain family 3 member B	Homo sapiens	231-233
34656853-0	2022	A sandwiched photoelectrochemical biosensing platform for detecting Cytokeratin-19 fragments based on Ag2S-sensitized BiOI/Bi2S3 heterostructure amplified by sulfur and nitrogen co-doped carbon quantum dots.	Nitrogen	169-177	keratin 19	Homo sapiens	68-82
34656853-0	2022	A sandwiched photoelectrochemical biosensing platform for detecting Cytokeratin-19 fragments based on Ag2S-sensitized BiOI/Bi2S3 heterostructure amplified by sulfur and nitrogen co-doped carbon quantum dots.	Nitrogen	169-177	angiotensin II receptor type 1	Homo sapiens	102-106
18245087-0	2008	Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.	Nitrogen	27-35	Gat1p	Saccharomyces cerevisiae S288C	93-97
34487927-1	2022	The nitrogen-doped carbon (NC) coating encapsulating heterostructural Sn/SnO2 microcube powders (Sn/SnO2@NC) are successfully fabricated through hydrothermal, polymerization of hydrogel, and carbonization processes, in which the SnO precursor powders exhibit regular microcube structure and uniform size distribution in the presence of optimized N2H4 H2O (3.0 mL of 1.0 mol/L).	Nitrogen	4-12	strawberry notch homolog 1	Homo sapiens	100-103
34487927-1	2022	The nitrogen-doped carbon (NC) coating encapsulating heterostructural Sn/SnO2 microcube powders (Sn/SnO2@NC) are successfully fabricated through hydrothermal, polymerization of hydrogel, and carbonization processes, in which the SnO precursor powders exhibit regular microcube structure and uniform size distribution in the presence of optimized N2H4 H2O (3.0 mL of 1.0 mol/L).	Nitrogen	4-12	strawberry notch homolog 1	Homo sapiens	229-232
35325216-7	2022	Among the glutamine synthetase (GS) family genes, we found that BnaA2.Gln1;4, significantly responsive to low-nitrogen conditions, showed higher transcription abundance and GS activity in the leaf veins, flower sepals, root cortex and stele, silique petiole, and stem tissues.	Nitrogen	110-118	glutamine synthetase 1;4	Arabidopsis thaliana	70-76
35325216-9	2022	The heterologous overexpression of BnaA2.Gln1;4 in Arabidopsis increased plant biomass, NUE, GS activity, and total amino acid concentrations under both sufficient- and low-nitrogen conditions.	Nitrogen	173-181	glutamine synthetase 1;4	Arabidopsis thaliana	41-47
18245087-1	2008	The Tor1,2 protein kinases globally influence many cellular processes including nitrogen-responsive gene expression that correlates with intracellular localization of GATA transcription activators Gln3 and Gat1/Nil1.	Nitrogen	80-88	Gat1p	Saccharomyces cerevisiae S288C	206-210
34965734-4	2022	Although high levels of reactive oxygen and nitrogen species (RONS) are produced during viral infections, it is not clear how they affect the RBD structure and its binding to ACE2 and GRP78.	Nitrogen	44-52	angiotensin converting enzyme 2	Homo sapiens	175-179
35219056-5	2022	In view of toxic gases released, catalytic oxidation employing in-situ generation of roasting slag at 600  C (AS1) can be effectively used for the conversion of (CN)2 to N2 under the optimal conditions of airflow rate of 0.7 L/min and AS1/ASs mass ratio of 0.5.	Nitrogen	170-172	prostaglandin D2 receptor	Homo sapiens	110-113
18245087-1	2008	The Tor1,2 protein kinases globally influence many cellular processes including nitrogen-responsive gene expression that correlates with intracellular localization of GATA transcription activators Gln3 and Gat1/Nil1.	Nitrogen	80-88	Gat1p	Saccharomyces cerevisiae S288C	211-215
35219056-5	2022	In view of toxic gases released, catalytic oxidation employing in-situ generation of roasting slag at 600  C (AS1) can be effectively used for the conversion of (CN)2 to N2 under the optimal conditions of airflow rate of 0.7 L/min and AS1/ASs mass ratio of 0.5.	Nitrogen	170-172	prostaglandin D2 receptor	Homo sapiens	235-238
18245087-2	2008	Gln3-Myc(13) and Gat1-Myc(13) are restricted to the cytoplasm of cells provided with good nitrogen sources, e.g. glutamine.	Nitrogen	90-98	Gat1p	Saccharomyces cerevisiae S288C	17-21
18327935-1	2008	A tetrapodal pentadentate nitrogen ligand (2,6-bis(1,1-di(aminomethyl)ethyl)pyridine, 1) is used for the synthesis of the azido-iron(III) complex [(1)Fe(N3)]X2 where X is either Br or PF6.	Nitrogen	26-34	sperm associated antigen 17	Homo sapiens	184-187
34874208-11	2022	However, the diet NC1+GAA had 11.2% higher nitrogen retention coefficient compared to the NC1 diet (P=0.038).6.	Nitrogen	43-51	alpha glucosidase 2	Gallus gallus	22-25
18033687-3	2008	Our study analyzed various solid tumor types for the expression of Dkk-3, a cystein-rich, N-glycosylated secreted member of the Dickkopf protein family that has been proposed as a tumor suppressor gene.	Nitrogen	90-91	dickkopf WNT signaling pathway inhibitor 3	Mus musculus	67-72
35064279-1	2022	Visible-near infrared spectroscopy is considered an effective method for rapidly determining total carbon (TC) and total nitrogen (TN) in terrestrial soils.	Nitrogen	121-129	C-type lectin domain family 3 member B	Homo sapiens	131-133
35183587-1	2022	Owing to membrane penetration, a novel route of nitrogen removal was proposed in a dual-chamber microbial fuel cell with a proton exchange membrane (PEM).	Nitrogen	48-56	mucin 1, cell surface associated	Homo sapiens	149-152
17957771-1	2008	The human insulin receptor (IR) homodimer is heavily glycosylated and contains a total of 19 predicted N-linked glycosylation sites in each monomer.	Nitrogen	103-104	insulin receptor	Homo sapiens	10-26
35500091-0	2022	Abatement of Nitrogen Oxides via Selective Catalytic Reduction over Ce1-W1 Atom-Pair Sites.	Nitrogen	13-21	carboxylesterase 1	Homo sapiens	68-71
35579458-5	2022	We found the sinking of Trichodesmium into deep water was far more efficient than that of Prochlorococcus, suggesting Trichodesmium blooms might be an essential carbon and nitrogen source for the maintenance of the BoB OMZ.	Nitrogen	172-180	G protein-coupled receptor 15	Homo sapiens	215-218
18335144-1	2008	The reactions of boron halides with free base porphyrins under conditions where partial hydrolysis of the boron halides can occur give diboron porphyrin complexes containing BOB moieties in which each boron is bonded to two porphyrin nitrogen atoms.	Nitrogen	234-242	G protein-coupled receptor 15	Homo sapiens	174-177
35579458-9	2022	It seems that the nitrite-N was not further reduced to nitrogen through denitrification but likely oxidized to nitrate by Nitrospinae in the BoB OMZ and then accumulated in the form of nitrate-N.	Nitrogen	55-63	G protein-coupled receptor 15	Homo sapiens	141-144
35579458-10	2022	However, the lack of N2 production in the BoB would change if the BoB OMZ became anoxic.	Nitrogen	21-23	G protein-coupled receptor 15	Homo sapiens	42-45
35579458-11	2022	Together, these results suggested that reduction of oxygen concentration and OMZ expansion may increase the use of nitrate by SAR11 and N2 production in the BoB.	Nitrogen	136-138	G protein-coupled receptor 15	Homo sapiens	157-160
35579458-13	2022	We demonstrate the prokaryotic community and its potential functions in nitrogen metabolism in the Bay of Bengal (BoB), where oxygen concentration is barely above suboxic level.	Nitrogen	72-80	G protein-coupled receptor 15	Homo sapiens	114-117
35579458-14	2022	This study highlighted that Trichodesmium might be an essential carbon and nitrogen source in the maintenance of the BoB OMZ.	Nitrogen	75-83	G protein-coupled receptor 15	Homo sapiens	117-120
35579458-15	2022	Additionally, we suggest that the lack of N2 production in the BoB would change if the BoB OMZ became anoxic, and the expansion of OMZs in the global ocean may potentially increase the use of nitrate by SAR11.	Nitrogen	42-44	G protein-coupled receptor 15	Homo sapiens	63-66
35579458-15	2022	Additionally, we suggest that the lack of N2 production in the BoB would change if the BoB OMZ became anoxic, and the expansion of OMZs in the global ocean may potentially increase the use of nitrate by SAR11.	Nitrogen	42-44	G protein-coupled receptor 15	Homo sapiens	87-90
35594678-4	2022	The average GB values of Cu, Zn, Cd, Pb, Cr, total carbon (TC), total nitrogen (TN) and total phosphorus (TP) are 45.14 mg/kg, 86.99 mg/kg, 0.29 mg/kg, 33.71 mg/kg, 110.90 mg/kg, 17.20 mg/g, 1.60 mg/g, and 665.78 mg/kg, respectively.	Nitrogen	70-78	C-type lectin domain family 3 member B	Homo sapiens	80-82
18344319-0	2008	Systems approach identifies an organic nitrogen-responsive gene network that is regulated by the master clock control gene CCA1.	Nitrogen	39-47	circadian clock associated 1	Arabidopsis thaliana	123-127
35629563-3	2022	By means of using the EC etching technique, the n++-layers can be converted into nanoporous (NP) layers whilst the undoped GaN remains intact, leading to a significantly high contrast in refractive index between NP-layer and undoped GaN and thus forming a DBR.	Nitrogen	48-49	gigaxonin	Homo sapiens	233-236
18344319-9	2008	Phase response curve analysis shows that distinct N-metabolites can advance or delay the CCA1 phase.	Nitrogen	50-51	circadian clock associated 1	Arabidopsis thaliana	89-93
18220364-7	2008	Formation of the complex with 7-methyl-GTP makes the eIF4E structure more compact, while binding of N (2), N (2),7-trimethyl-GTP leads to higher solvent accessibility of the protein backbone in comparison with the apo form.	Nitrogen	100-105	eukaryotic translation initiation factor 4E	Homo sapiens	53-58
35533086-3	2022	During a MERTK inhibitor lead optimization project, a series containing a biphenyl ring system with benzylamine meta-substitution on one phenyl and nitrogen inclusion as the meta atom on the other ring demonstrated multiple routes of compound elimination in rats.	Nitrogen	148-156	MER proto-oncogene, tyrosine kinase	Rattus norvegicus	9-14
35533206-10	2022	Furthermore, Pns11 potentially blocks autophagosome degradation by directly targeting and mediating the reduced expression of N-glycosylated Lamp1 on lysosomal membranes.	Nitrogen	126-127	lysosomal associated membrane protein 1	Homo sapiens	141-146
35150821-6	2022	The mitochondria-related gene ATP12, MRPL22, MRP1 and NAM9 significantly increased the utilization of multiple non-preferred amino acids and reduced accumulation of the urea by coordinately regulating nitrogen catabolism repression, Ssy1p-Ptr3p-Ssy5p signaling sensor system, amino acid transporters, TOR pathway and urea metabolism-related pathways.	Nitrogen	201-209	ATP synthase complex assembly protein ATP12	Saccharomyces cerevisiae S288C	30-35
35150821-6	2022	The mitochondria-related gene ATP12, MRPL22, MRP1 and NAM9 significantly increased the utilization of multiple non-preferred amino acids and reduced accumulation of the urea by coordinately regulating nitrogen catabolism repression, Ssy1p-Ptr3p-Ssy5p signaling sensor system, amino acid transporters, TOR pathway and urea metabolism-related pathways.	Nitrogen	201-209	mitochondrial 37S ribosomal protein NAM9	Saccharomyces cerevisiae S288C	54-58
18292673-10	2008	RESULTS: At clinical concentrations, methadone enantiomer N-demethylation by recombinant CYPs 2B6, 3A4, and 2C19 was S &gt; R, S = R, and S &lt;&lt; R. Greater stereoselective metabolism (S &gt; R) occurred in livers expressing high levels of CYP2B6 compared with CYP3A4.	Nitrogen	58-59	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	243-249
18060877-1	2008	Thyroglobulin (Tg) is a large molecule containing 2750 amino acids with a molecular weight of 330 kD and twenty putative N-linked glycosylation sites.	Nitrogen	121-122	thyroglobulin	Homo sapiens	0-13
35112714-0	2022	Differential N- and O-glycosylation signatures of HIV-1 Gag virus-like particles and coproduced extracellular vesicles.	Nitrogen	13-14	Pr55(Gag)	Human immunodeficiency virus 1	56-59
35112714-6	2022	In this work, porous graphitized carbon separation method coupled with mass spectrometry was used to characterize the N- and O- glycosylation profiles of Gag VLPs produced in HEK293 cells.	Nitrogen	118-119	Pr55(Gag)	Human immunodeficiency virus 1	154-157
18060877-1	2008	Thyroglobulin (Tg) is a large molecule containing 2750 amino acids with a molecular weight of 330 kD and twenty putative N-linked glycosylation sites.	Nitrogen	121-122	thyroglobulin	Homo sapiens	15-17
18166271-2	2008	Microinfusions of N/OFQ (10 or 32pmol) into the central amygdala (ACE) increased the time spent in the open arms of the elevated plus-maze (anxiolytic-like effects), whereas microinfusions of N/OFQ (10, 32 or 100 pmol) into the basolateral amygdala (ABL) did not affect the time spent in the open arms.	Nitrogen	18-19	ABL proto-oncogene 1, non-receptor tyrosine kinase	Rattus norvegicus	250-253
35124081-0	2022	Simultaneous partial nitrification, anammox, and denitrification in an upflow microaerobic membrane bioreactor treating middle concentration of ammonia nitrogen wastewater with low COD/TN ratio.	Nitrogen	152-160	C-type lectin domain family 3 member B	Homo sapiens	185-187
18399241-5	2008	In [Ru(pdto)(dpq)Cl](PF6) 2a with a distorted octahedral coordination geometry, one of the two py nitrogens of pdto is not coordinated.	Nitrogen	98-107	sperm associated antigen 17	Homo sapiens	21-24
35608094-2	2022	This labile Fe-N bond led to multiple unfolding/rupture pathways of mNT and its cluster by atomic force microscopy-based single-molecule force spectroscopy (AFM-SMFS), one of most common tools for characterizing the molecular mechanics.	Nitrogen	15-16	max binding protein	Mus musculus	68-71
18077586-0	2008	Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction.	Nitrogen	13-14	protein tyrosine phosphatase, non-receptor type 11	Mus musculus	54-58
35289411-0	2022	EDA-NOCV analysis of carbene-borylene bonded dinitrogen complexes for deeper bonding insight: A fair comparison with a metal-dinitrogen system.	Nitrogen	45-55	ectodysplasin A	Homo sapiens	0-3
35451542-0	2022	OPN N-glycosylation Promoted Bone Destruction.	Nitrogen	4-5	secreted phosphoprotein 1	Mus musculus	0-3
35451542-1	2022	OBJECTIVES: Exploring the role of OPN N-glycosylation in osteoblasts and osteoclasts.	Nitrogen	38-39	secreted phosphoprotein 1	Mus musculus	34-37
35451542-4	2022	The effect of OPN N-glycosylation on proliferation of osteoblasts and osteoclasts was detected by CCK8 assays.	Nitrogen	18-19	secreted phosphoprotein 1	Mus musculus	14-17
35451542-5	2022	Western blotting was used to detect the expression of OPN N-glycosylation on osteoclasts and osteoblasts.	Nitrogen	58-59	secreted phosphoprotein 1	Mus musculus	54-57
35451542-6	2022	Detection of N-glycosylation of OPN activated the NF-kappaB signaling pathway to regulate osteoblasts and osteoclasts.	Nitrogen	13-14	secreted phosphoprotein 1	Mus musculus	32-35
35451542-9	2022	The OPN N-glycosylation site was identified as 79 by MS. N-glycosylation of OPN promoted the proliferation of osteoclasts.	Nitrogen	8-9	secreted phosphoprotein 1	Mus musculus	4-7
35451542-9	2022	The OPN N-glycosylation site was identified as 79 by MS. N-glycosylation of OPN promoted the proliferation of osteoclasts.	Nitrogen	8-9	secreted phosphoprotein 1	Mus musculus	76-79
35451542-9	2022	The OPN N-glycosylation site was identified as 79 by MS. N-glycosylation of OPN promoted the proliferation of osteoclasts.	Nitrogen	57-58	secreted phosphoprotein 1	Mus musculus	76-79
35451542-11	2022	OPN N-glycosylation modulated the expression of osteoclast- and osteoblast-associated factors through the NF-kappaB signaling pathway.	Nitrogen	4-5	secreted phosphoprotein 1	Mus musculus	0-3
35451542-12	2022	N-glycosylation of OPN promoted nuclear translocation of NF-kappaB in osteoclasts and osteoblasts.	Nitrogen	0-1	secreted phosphoprotein 1	Mus musculus	19-22
35451542-13	2022	CONCLUSIONS: The N-glycosylation site of OPN is 79.	Nitrogen	17-18	secreted phosphoprotein 1	Mus musculus	41-44
35451542-14	2022	N-glycosylation of OPN played an important role in the biological function of OPN protein.	Nitrogen	0-1	secreted phosphoprotein 1	Mus musculus	19-22
35451542-14	2022	N-glycosylation of OPN played an important role in the biological function of OPN protein.	Nitrogen	0-1	secreted phosphoprotein 1	Mus musculus	78-81
34776532-2	2022	To investigate the effect of geometry and to find the significance of an enol form if any in DNPZ on acetylcholinesterase (AChE) inhibition, we changed the tetrahedral geometry of DNPZ to planar trigonal pyramidal geometry by replacing the alpha-carbon atom next to ketone functionality with a nitrogen atom.	Nitrogen	294-302	acetylcholinesterase	Mus musculus	101-121
16930998-6	2007	Small scale composting of the same material indicated less efficient reduction of faecal bacteria at temperatures around 50 degrees C. In the chemical treatment tested, an addition of 3% N-NH(3) increased the pH to above 9 within 1h and resulted in a good reduction in the indicator organisms for bacteria (Salmonella spp.	Nitrogen	187-188	histocompatibility minor 13	Homo sapiens	318-321
34341919-1	2022	A new multi-point inflow pre-anoxic/oxic/anaerobic/anoxic/oxic (A1/O2/A3/A4/O5) sludge-membrane coupling process and pilot plant were developed and designed to solve the problem of nitrogen and phosphorus removal of low carbon and nitrogen (C/N) ratio domestic sewage in southern China.	Nitrogen	181-189	immunoglobulin kappa variable 2D-36 (pseudogene)	Homo sapiens	70-78
34963682-4	2021	N2 adsorption-desorption isotherms indicate good BET surface area for Ni-CP; therefore can be employed as an efficient catalyst in multicomponent reactions for the synthesis of polyhydroquinoline and 2,3-dihydroquinazolin-4(1H)-one derivatives.	Nitrogen	0-2	delta/notch like EGF repeat containing	Homo sapiens	49-52
34893540-8	2021	Autophagic targeting of Cys/N-degron substrates is mediated by the autophagic N-recognin p62/SQTSM-1/Sequestosome-1 through recognition of K27/K63-linked ubiquitin (Ub) chains.	Nitrogen	28-29	keratin 27	Homo sapiens	139-142
35357149-5	2022	Arc-induced nitrogen oxide anions promoted the formation of characteristic adducts, such as (M+NO3)-, and improved the instrument response for all the explosives tested.	Nitrogen	12-20	activity regulated cytoskeleton associated protein	Homo sapiens	0-3
35191568-4	2022	EDA-NOCV analysis reveals strong binding of dinitrogen to these base-stabilized borylenes.	Nitrogen	44-54	ectodysplasin A	Homo sapiens	0-3
17761779-9	2007	These results strongly suggested that the N(1)- and N(2)-glucuronidation of FYX-051 is catalyzed mainly by UGT1A9 in human livers.	Nitrogen	52-56	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	107-113
17850059-3	2007	Nine additional NE inhibitors were identified through further screening of N-benzoylpyrazole analogues.	Nitrogen	0-1	elastase, neutrophil expressed	Homo sapiens	16-18
35450409-3	2022	In addition to the direct association between I-R and the release of reactive oxygen species and reactive nitrogen species, it is involved in developing mitochondrial oxidative damage.	Nitrogen	106-114	insulin receptor	Homo sapiens	46-49
33535880-4	2021	For XY688, PASPN treatment had the largest nitrogen uptake in grain, up to 3.14 kg/hm2, and PASPN treatment increased 17.4% compared with N0.	Nitrogen	43-51	Putative anthocyanidin reductase	Zea mays	83-86
33535880-6	2021	Nitrogen uptake was 3.16 kg/hm2, which increased 37.4% compared with N0.	Nitrogen	0-8	Putative anthocyanidin reductase	Zea mays	28-31
34024253-10	2021	Altogether, PTHrP can inhibit nitrogen-containing BP-induced apoptosis of HPdLFs by activating MKP1 phosphatase.	Nitrogen	30-38	parathyroid hormone like hormone	Homo sapiens	12-17
17579843-5	2007	The result of the BALF proteome analysis show the presence of several isoforms of SP-A, in which an N-non-glycosylierte form and several proline hydroxylations were identified.	Nitrogen	100-101	surfactant protein A1	Homo sapiens	82-86
34951277-10	2021	Considering all the indicators, irrigating at 600 m3 hm-2 during the overwintering period plus applying nitrogen at 150 kg hm-2 could achieve high yield, high efficiency, and environment friendly development of winter wheat in the Guanzhong Plain of Shaanxi.	Nitrogen	104-112	cholinergic receptor muscarinic 2	Homo sapiens	123-127
35397015-0	2022	Electrochemical immuno determination of connective tissue growth factor levels on nitrogen-doped graphene.	Nitrogen	82-90	cellular communication network factor 2	Homo sapiens	40-71
35397015-2	2022	In this work, a three-dimensional pore structure of alkali-activated nitrogen-doped graphene (aN-G) was used as an electrode modification material, and a label-free electrochemical immunosensor for the sensitive detection of CTGF was successfully constructed by the formation of an amide bond between amino groups in protein and carboxyl groups on the carbon surface.	Nitrogen	69-77	cellular communication network factor 2	Homo sapiens	225-229
17685375-5	2007	The BET surface area for the mesoporous carbonaceous samples calcined at 600 degrees C under nitrogen atmosphere is around 600 m2 g(-1), and the pore size can be adjusted from 2.8 to 5.4 nm.	Nitrogen	93-101	delta/notch like EGF repeat containing	Homo sapiens	4-7
35464935-6	2022	The expression level of CrPrp19 was suppressed by nitrogen or sulfur deficiency.	Nitrogen	50-58	uncharacterized protein	Chlamydomonas reinhardtii	24-31
35146943-2	2022	The study aimed to investigate the relationship between the blood urea nitrogen to serum albumin ratio (BAR) and the prognosis of patients with CHF admitted to the ICU.	Nitrogen	71-79	bifunctional apoptosis regulator	Homo sapiens	104-107
35191215-9	2022	The SDR exceeded the MCID (19 Nm) for strength in response to LEU-PRO (25 Nm (-29, 45)) and LEU-PRO+n-3 (23 Nm (-29, 43)) supplementation but the effect was uncertain, evidenced by wide confidence intervals.	Nitrogen	100-101	caveolae associated protein 2	Homo sapiens	4-7
34822898-1	2022	The oxygen based membrane biofilm (O2-MBfR) has been proved to be a novel technology in treating greywater (GW) and response surface methodology (RSM) was used to model the removal of chemical oxygen demand (COD) and total nitrogen (TN) with operation parameters COD/TN ratio, system pH and lumen air pressure (LAP).	Nitrogen	223-231	C-type lectin domain family 3 member B	Homo sapiens	233-235
17672841-2	2007	Two T-DNA insertion lines, atdur3-1 and atdur3-3, that showed impaired growth on urea as a sole nitrogen source were used to investigate a role of the H+/urea co-transporter AtDUR3 in nitrogen nutrition in Arabidopsis.	Nitrogen	184-192	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	174-180
34553505-3	2021	Based on the structure-activity relationship and in vitro 2D NMR studies employing 15 N-labeled IL-33, we identified that the oxazolo(4,5- c )-quinolinone analog 7c binds to the interface region of IL-33 and IL-33 receptor (ST2), an orphan receptor of the IL-1 receptor family.	Nitrogen	86-87	interleukin 33	Homo sapiens	96-101
34553505-3	2021	Based on the structure-activity relationship and in vitro 2D NMR studies employing 15 N-labeled IL-33, we identified that the oxazolo(4,5- c )-quinolinone analog 7c binds to the interface region of IL-33 and IL-33 receptor (ST2), an orphan receptor of the IL-1 receptor family.	Nitrogen	86-87	interleukin 33	Homo sapiens	198-203
34494876-0	2021	Analysis of the Role of N-Linked Glycosylation in Cell Surface Expression, Function, and Binding Properties of SARS-CoV-2 Receptor ACE2.	Nitrogen	24-25	angiotensin converting enzyme 2	Homo sapiens	131-135
34494876-5	2021	However, the contribution of N-glycosylation to ACE2 function is poorly understood.	Nitrogen	29-30	angiotensin converting enzyme 2	Homo sapiens	48-52
34494876-7	2021	The elimination of N-glycosylation by tunicamycin (TM) treatment, or mutagenesis, showed that N-glycosylation is critical for the proper cell surface expression of ACE2 but not for its carboxiprotease activity.	Nitrogen	19-20	angiotensin converting enzyme 2	Homo sapiens	164-168
35089338-0	2022	The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis.	Nitrogen	111-119	carbon/nitrogen insensitive 1	Arabidopsis thaliana	56-61
35089338-4	2022	Here, we report that the Arabidopsis thaliana trans-Golgi network/early endosome (TGN/EE) localized SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein SYP61 interacts with the transmembrane ubiquitin ligase ATL31, a key regulator of resistance to disrupted carbon (C)/nitrogen/(N)-nutrient conditions.	Nitrogen	303-311	carbon/nitrogen insensitive 1	Arabidopsis thaliana	242-247
35234919-0	2022	Concerted action: SYP61 and ATL31 cooperatively regulate the carbon/nitrogen nutrient response in Arabidopsis.	Nitrogen	68-76	carbon/nitrogen insensitive 1	Arabidopsis thaliana	28-33
34494876-7	2021	The elimination of N-glycosylation by tunicamycin (TM) treatment, or mutagenesis, showed that N-glycosylation is critical for the proper cell surface expression of ACE2 but not for its carboxiprotease activity.	Nitrogen	94-95	angiotensin converting enzyme 2	Homo sapiens	164-168
17672841-3	2007	In transgenic lines expressing AtDUR3-promoter:GFP constructs, promoter activity was upregulated under nitrogen deficiency and localized to the rhizodermis, including root hairs, as well as to the cortex in more basal root zones.	Nitrogen	103-111	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	31-37
34494876-10	2021	Impairment of hACE2 N-glycosylation decreased cell-to-cell fusion mediated by SARS-CoV S protein but not that mediated by SARS-CoV-2 S protein.	Nitrogen	20-21	angiotensin converting enzyme 2	Homo sapiens	14-19
34494876-11	2021	Finally, we found that hACE2 N-glycosylation is required for an efficient viral entry of SARS-CoV/SARS-CoV-2 S pseudotyped viruses, which may be the result of low cell surface expression of the deglycosylated ACE2 receptor.	Nitrogen	29-30	angiotensin converting enzyme 2	Homo sapiens	23-28
35387078-0	2022	The Antibody Response Against Neuraminidase in Human Influenza A (H3N2) Virus Infections During 2018/2019 Flu Season: Focusing on the Epitopes of 329-N-Glycosylation and E344 in N2.	Nitrogen	150-151	neuraminidase 1	Homo sapiens	30-43
35387078-0	2022	The Antibody Response Against Neuraminidase in Human Influenza A (H3N2) Virus Infections During 2018/2019 Flu Season: Focusing on the Epitopes of 329-N-Glycosylation and E344 in N2.	Nitrogen	178-180	neuraminidase 1	Homo sapiens	30-43
34494876-11	2021	Finally, we found that hACE2 N-glycosylation is required for an efficient viral entry of SARS-CoV/SARS-CoV-2 S pseudotyped viruses, which may be the result of low cell surface expression of the deglycosylated ACE2 receptor.	Nitrogen	29-30	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	109-110
17672841-5	2007	Expression of the AtDUR3 gene in nitrogen-deficient roots was repressed by ammonium and nitrate but induced after supply of urea.	Nitrogen	33-41	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	18-24
17960045-0	2007	[Effects of different nitrogen application rate on allocation of photosynthetic electron flux in Rumex K-1 leaves].	Nitrogen	22-30	keratin 1	Homo sapiens	103-106
34173222-10	2021	In this work we report the 1H, 15 N and 13C backbone resonance assignments of human XRCC4 in the solution form of the 1-164 construct.	Nitrogen	34-35	X-ray repair cross complementing 4	Homo sapiens	84-89
35238539-0	2022	Interfacial Electron Regulation of Rh Atomic Layer-Decorated SnO2 Heterostructures for Enhancing Electrocatalytic Nitrogen Reduction.	Nitrogen	114-122	strawberry notch homolog 1	Homo sapiens	61-64
17623277-8	2007	A single N-glycosylation site (Asn285 -Glu-Thr) was identified in DCE and was proven to be fully glycosylated.	Nitrogen	9-10	24-dehydrocholesterol reductase	Homo sapiens	66-69
35262821-10	2022	The dep1 mutant exhibited improved grain quality without severe yield penalty under nitrogen reduction conditions.	Nitrogen	84-92	protein tyrosine phosphatase receptor type J	Homo sapiens	4-8
17580944-2	2007	The BET analysis is the standard method for determining surface areas from nitrogen adsorption isotherms and was originally derived for multilayer gas adsorption onto flat surfaces.	Nitrogen	75-83	delta/notch like EGF repeat containing	Homo sapiens	4-7
35239649-3	2022	We recovered a hypothetical gene YLR053c, renamed NRS1 for Nitrogen-Responsive Start regulator 1, which encodes a poorly characterized 108 amino acid microprotein.	Nitrogen	59-67	uncharacterized protein	Saccharomyces cerevisiae S288C	33-40
34310986-6	2021	Additionally, the increased frequency of CD19+CD138+ plasma cells was positively associated with urea nitrogen in the new-onset groups.	Nitrogen	102-110	CD19 molecule	Homo sapiens	41-45
34310986-6	2021	Additionally, the increased frequency of CD19+CD138+ plasma cells was positively associated with urea nitrogen in the new-onset groups.	Nitrogen	102-110	syndecan 1	Homo sapiens	46-51
34214792-2	2021	This study aimed to develop and validate equations for N outputs in manure, urine and faeces for animals under diets with contrasting crude protein (CP) concentrations.	Nitrogen	55-56	ceruloplasmin	Bos taurus	149-151
34214792-10	2021	However, in beef cattle fed medium or high CP concentration diets, using equations that have been developed from animals fed similar CP concentration diets, substantially improves the prediction accuracy of N outputs in manure, urine and faeces in most cases.	Nitrogen	207-208	ceruloplasmin	Bos taurus	43-45
17674741-2	2007	Results show that nitrogen and phosphorus surplus in China are 640 x 10(4) t and 98 x 10(4) t respectively, and nitrogen and phosphorus surplus intensity in China are 16.56 kg/hm2 and 2.53 kg/hm2 respectively.	Nitrogen	112-120	cholinergic receptor muscarinic 2	Homo sapiens	176-185
34646995-4	2021	Generated putative ITGA2 N-glycosite mutants halted collagen and laminin binding and cells lacking N-glycosylated ITGA2 were marginally adherent to collagen, likely associated with its enhanced proteasome degradation through poly-ubiquitination.	Nitrogen	99-100	integrin subunit alpha 2	Homo sapiens	114-119
34671446-1	2021	Different five-membered nitrogen-containing heteroaromatics in the position of the typical electrophilic group in prolyl oligopeptidase (PREP) inhibitors were investigated and compared to tetrazole.	Nitrogen	24-32	prolyl endopeptidase	Homo sapiens	114-135
35164559-1	2022	Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) extensively N-glycosylates its spike proteins, which are necessary for host cell invasion and the target of both vaccines and immunotherapies.	Nitrogen	73-74	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	92-97
35216131-4	2022	NADPH, as produced from the action of glucose-6-phosphate dehydrogenase (G6PD), has an important role in redox homeostasis, serving as a cofactor for glutathione reductase in the recycling of glutathione from oxidized glutathione and for NADPH oxidases and nitric oxide synthases in the generation of reactive oxygen (ROS) and nitrogen species (RNS).	Nitrogen	327-335	glutathione-disulfide reductase	Homo sapiens	150-171
35040258-2	2022	The Fat-1 gene can express the n-3 fatty acid desaturase, which converts n-6 polyunsaturated fatty acids (PUFA) to n-3 PUFAs.	Nitrogen	31-32	LOW QUALITY PROTEIN: protocadherin Fat 1	Oryctolagus cuniculus	4-9
34506606-1	2021	The purpose of this study was to investigate the effects of oscillating crude protein (CP) concentration diet on the nitrogen utilization efficiency (NUE) of calves and determine its mechanism.	Nitrogen	117-125	ceruloplasmin	Bos taurus	87-89
34380307-5	2021	In contrast, the Si-N bond of the analogous vinylidene (R2(Me2N)Si-(R)Si (NHC)Ge:) (obtained by nucleophilic substitution of Cl by NMe2) does not oxidatively add to Ni(0), and a hydridosilagermene-eta2-nickel complex is obtained instead.	Nitrogen	20-21	DNA polymerase iota	Homo sapiens	197-201
17654947-2	2007	In this paper, we report the results of FTIR, Raman, and TGA studies to confirm the presence of N-doping inside carbon nanotubes.	Nitrogen	96-97	T-box transcription factor 1	Homo sapiens	57-60
34062155-8	2021	Using a yeast torsinA expression system, we demonstrate that a specific protein disulfide isomerase, Pdi1, affects the folding and N-linked glycosylation of torsinA and torsinA E in a redox-dependent manner, suggesting that the acquisition of early torsinA folding intermediates is sensitive to perturbed interactions between Cys residues and the quality control machinery.	Nitrogen	131-132	protein disulfide isomerase PDI1	Saccharomyces cerevisiae S288C	101-105
35125886-1	2022	Background: We hypothesized that the blood urea nitrogen (BUN) to serum albumin ratio (BAR) could serve as an independent predictor for incident acute kidney injury (AKI) in intensive care unit (ICU) patients with rib fracture.	Nitrogen	48-56	bifunctional apoptosis regulator	Homo sapiens	87-90
17509134-0	2007	Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.	Nitrogen	25-26	O-GlcNAcase	Homo sapiens	55-82
35014656-0	2022	Nitrogen reduction reaction on single cluster catalysts of defective PC6-trimeric or tetrameric transition metal.	Nitrogen	0-8	proprotein convertase subtilisin/kexin type 5	Homo sapiens	69-72
35014656-4	2022	In order to find an effective way of reducing N2 into NH3, in this work, PC6 monolayers with good electro-optical properties and eight transition metals (V, Cr, Mn, Fe, Co, Ni, Cu, Zn) are chosen to construct PC6-TM3 and PC6-TM4 single cluster catalysts (SCCs), which are proved to have low overpotential, multiple active-sites and superior activity.	Nitrogen	46-48	proprotein convertase subtilisin/kexin type 5	Homo sapiens	73-76
35014656-4	2022	In order to find an effective way of reducing N2 into NH3, in this work, PC6 monolayers with good electro-optical properties and eight transition metals (V, Cr, Mn, Fe, Co, Ni, Cu, Zn) are chosen to construct PC6-TM3 and PC6-TM4 single cluster catalysts (SCCs), which are proved to have low overpotential, multiple active-sites and superior activity.	Nitrogen	46-48	proprotein convertase subtilisin/kexin type 5	Homo sapiens	209-212
35014656-4	2022	In order to find an effective way of reducing N2 into NH3, in this work, PC6 monolayers with good electro-optical properties and eight transition metals (V, Cr, Mn, Fe, Co, Ni, Cu, Zn) are chosen to construct PC6-TM3 and PC6-TM4 single cluster catalysts (SCCs), which are proved to have low overpotential, multiple active-sites and superior activity.	Nitrogen	46-48	proprotein convertase subtilisin/kexin type 5	Homo sapiens	221-224
35014656-6	2022	(PC6-Co3, PC6-Fe4)/(PC6-V3, PC6-Cr3)/(PC6-V4, PC6-Mn4) prefer to adsorb N2 rather than H in the end-on/side-on I/side-on III mode.	Nitrogen	72-74	proprotein convertase subtilisin/kexin type 5	Homo sapiens	1-4
34198201-2	2021	Despite the ongoing rise in scientific production on spatiotemporal distribution characteristics of water quality parameters, such as total nitrogen (TN) in reservoirs, attempts to use published data and incorporate them into a large-scale comparison and trends analyses are lacking.	Nitrogen	140-148	C-type lectin domain family 3 member B	Homo sapiens	150-152
35014656-6	2022	(PC6-Co3, PC6-Fe4)/(PC6-V3, PC6-Cr3)/(PC6-V4, PC6-Mn4) prefer to adsorb N2 rather than H in the end-on/side-on I/side-on III mode.	Nitrogen	72-74	proprotein convertase subtilisin/kexin type 5	Homo sapiens	20-23
17322565-8	2007	These data suggest that N-linked glycosylation at Asn-116 reduces the ability of EL to hydrolyze lipids in LDL and HDL2.	Nitrogen	24-25	junctophilin 3	Homo sapiens	115-119
35014656-6	2022	(PC6-Co3, PC6-Fe4)/(PC6-V3, PC6-Cr3)/(PC6-V4, PC6-Mn4) prefer to adsorb N2 rather than H in the end-on/side-on I/side-on III mode.	Nitrogen	72-74	proprotein convertase subtilisin/kexin type 5	Homo sapiens	28-31
35014656-6	2022	(PC6-Co3, PC6-Fe4)/(PC6-V3, PC6-Cr3)/(PC6-V4, PC6-Mn4) prefer to adsorb N2 rather than H in the end-on/side-on I/side-on III mode.	Nitrogen	72-74	proprotein convertase subtilisin/kexin type 5	Homo sapiens	38-41
34264383-2	2021	The TPE@SNW-1 was characterized with different techniques of Fourier transform infrared spectroscopy, X-ray diffraction, transmission electron microscopy, scanning electron microscopy, and nitrogen adsorption/desorption experiments.	Nitrogen	189-197	SNW domain containing 1	Homo sapiens	8-13
17378553-6	2007	These studies indicated that the copper center in the CuL1 complex adopts a square-pyramidal geometry with the four nitrogen atoms of the macrocycle forming the equatorial plane and a water molecule at axial position, and the copper in the CuL2 complex is square-planar.	Nitrogen	116-124	cullin 1	Homo sapiens	54-58
34182225-17	2021	Particularly, a surplus of nitrogen supply via the aminogenic diet affected metabolic responses and stimulated insulin and glucagon secretion.	Nitrogen	27-35	glucagon	Bos taurus	123-131
34085593-5	2021	Conversely, absence of a nitrogen source suppresses TORC1 in a manner dependent on GATOR1 as well as the Tsc1-Tsc2 complex, whose mammalian equivalent functions as a growth-factor sensitive TORC1 inhibitor.	Nitrogen	25-33	CREB regulated transcription coactivator 1	Homo sapiens	52-57
34085593-5	2021	Conversely, absence of a nitrogen source suppresses TORC1 in a manner dependent on GATOR1 as well as the Tsc1-Tsc2 complex, whose mammalian equivalent functions as a growth-factor sensitive TORC1 inhibitor.	Nitrogen	25-33	CREB regulated transcription coactivator 1	Homo sapiens	190-195
35014832-2	2022	NEU1 is biosynthesized in the endoplasmic reticulum (ER) lumen as an N-glycosylated protein.	Nitrogen	69-70	neuraminidase 1	Homo sapiens	0-4
35055047-0	2022	COE2 Is Required for the Root Foraging Response to Nitrogen Limitation.	Nitrogen	51-59	EBF transcription factor 2	Homo sapiens	0-4
17289383-1	2007	A series of N-substituted analogs based upon the spiropiperidine core of 1 was synthesized and exhibited high binding affinity to the nociceptin (NOP) receptor.	Nitrogen	12-13	opioid related nociceptin receptor 1	Homo sapiens	134-159
35087496-3	2021	In a chemically defined medium, using milk and lupin proteins as sole nitrogen source, two proteolytic strains were able to sustain the growth of non-proteolytic strains, but one did not.	Nitrogen	70-78	5'-nucleotidase, cytosolic IIIA	Homo sapiens	47-52
34209622-8	2021	The alterations of IgG N-glycome, illustrated here for the first time in HDC, demonstrate a biomarker potential, which may shed light on future studies investigating their potential for monitoring or preventing the progression from HTN or T2DM towards HDC.	Nitrogen	23-24	histidine decarboxylase	Homo sapiens	73-76
34241210-5	2021	Three different coordination modes (end-on, side-on, and linear NMoN) have been considered for the triatomic (MoN2)n. Our results demonstrate that the reduced states of such systems lead to a greater degree of N2 activation, which can be the starting point of different reaction channels.	Nitrogen	210-212	MON2 homolog, regulator of endosome-to-Golgi trafficking	Homo sapiens	110-114
34122489-10	2021	The oat-lupin mixture showed strong competitive interactions, where lupin eventually overyielded due to reliance on atmospheric N and stronger competitiveness for soil P compared to oat.	Nitrogen	128-129	5'-nucleotidase, cytosolic IIIA	Homo sapiens	8-13
34122489-10	2021	The oat-lupin mixture showed strong competitive interactions, where lupin eventually overyielded due to reliance on atmospheric N and stronger competitiveness for soil P compared to oat.	Nitrogen	128-129	5'-nucleotidase, cytosolic IIIA	Homo sapiens	68-73
34974624-0	2022	UCP1 and AOX1a contribute to regulation of carbon and nitrogen metabolism and yield in Arabidopsis under low nitrogen stress.	Nitrogen	54-62	alternative oxidase 1A	Arabidopsis thaliana	9-14
35140555-6	2022	Combinatorial targeting of the promoter regions of both aceE and pdhR in E. coli MG1655 pdCas9 psgRNA_aceE_234_pdhR_329 resulted in the stable aerobic production of pyruvate with non-growing cells at YP/S  =  0.36 +- 0.029 gPyruvate/gGlucose in lab-scale bioreactors throughout an extended nitrogen-limited production phase.	Nitrogen	290-298	DNA-binding transcriptional dual regulator PdhR	Escherichia coli str. K-12 substr. MG1655	65-69
35140555-6	2022	Combinatorial targeting of the promoter regions of both aceE and pdhR in E. coli MG1655 pdCas9 psgRNA_aceE_234_pdhR_329 resulted in the stable aerobic production of pyruvate with non-growing cells at YP/S  =  0.36 +- 0.029 gPyruvate/gGlucose in lab-scale bioreactors throughout an extended nitrogen-limited production phase.	Nitrogen	290-298	DNA-binding transcriptional dual regulator PdhR	Escherichia coli str. K-12 substr. MG1655	111-115
17371021-6	2007	When the Schiff base nitrogen atoms of the adducts carry an aliphatic substituent such as in the internal and external aldimines of PLP in the enzymatic environment, protonation of the ring nitrogen shifts the proton in the intramolecular OHN hydrogen bond from the oxygen to the Schiff base nitrogen.	Nitrogen	21-29	pyridoxal phosphatase	Homo sapiens	132-135
34069872-2	2021	SNAP29 is a soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein.	Nitrogen	20-21	synaptosome associated protein 29	Homo sapiens	0-6
34066902-2	2021	The effect of GAT1 gene, the GATA transcription activator, on higher alcohol biosynthesis was investigated to clarify the mechanism of Saccharomyces cerevisiae regulating higher alcohol metabolism under high concentrations of free amino nitrogen (FAN).	Nitrogen	237-245	Gat1p	Saccharomyces cerevisiae S288C	14-18
34495528-6	2021	Subsequently, the N-glycosylated nascent proteins enter the folding step, in which N-glycans contribute largely to attaining the correct protein fold by recruiting the lectin-like chaperones, calnexin, and calreticulin.	Nitrogen	18-19	calnexin	Homo sapiens	192-200
17371021-6	2007	When the Schiff base nitrogen atoms of the adducts carry an aliphatic substituent such as in the internal and external aldimines of PLP in the enzymatic environment, protonation of the ring nitrogen shifts the proton in the intramolecular OHN hydrogen bond from the oxygen to the Schiff base nitrogen.	Nitrogen	190-198	pyridoxal phosphatase	Homo sapiens	132-135
17371021-6	2007	When the Schiff base nitrogen atoms of the adducts carry an aliphatic substituent such as in the internal and external aldimines of PLP in the enzymatic environment, protonation of the ring nitrogen shifts the proton in the intramolecular OHN hydrogen bond from the oxygen to the Schiff base nitrogen.	Nitrogen	190-198	pyridoxal phosphatase	Homo sapiens	132-135
34332121-6	2021	The dataset created for identifying the EDEM2 glyco-clients carrying high mannose/hybrid N-glycans provides a comprehensive N-glycosites analysis mapping over 1000 N-glycosites on more than 600 melanoma glycoproteins.	Nitrogen	124-125	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	40-45
17301828-8	2007	These results indicate that R62W influences the stability of membrane CD23 molecules due to possibly diminished N-glycosylation.	Nitrogen	112-113	Fc epsilon receptor II	Homo sapiens	70-74
34332121-6	2021	The dataset created for identifying the EDEM2 glyco-clients carrying high mannose/hybrid N-glycans provides a comprehensive N-glycosites analysis mapping over 1000 N-glycosites on more than 600 melanoma glycoproteins.	Nitrogen	164-165	ER degradation enhancing alpha-mannosidase like protein 2	Homo sapiens	40-45
35525361-7	2022	The results indicate that changes in the total nitrogen (TN) to total phosphorus (TP) ratio correlated with changes in the BF contribution; whereas the quantity of OC was mainly correlated with TN.	Nitrogen	47-55	C-type lectin domain family 3 member B	Homo sapiens	57-59
35390370-5	2022	High loading rates of organic matter, ammonia nitrogen and total nitrogen (TN) in the MABR using the hot-pressed membrane were 154.9 +- 5.4 g COD/(m2 d), 25.5 +- 0.6 g N/(m2 d) and 22.6 +- 0.7 g N/(m2 d), respectively.	Nitrogen	65-73	C-type lectin domain family 3 member B	Homo sapiens	75-77
35302037-4	2022	According to the results achieved, the total N (TN) loss mainly occurred during the initial 12 days when the soil was flooded, then presented N immobilized by soil and finally, basically balanced between influent and effluent after 50 days.	Nitrogen	45-46	C-type lectin domain family 3 member B	Homo sapiens	48-50
35302037-4	2022	According to the results achieved, the total N (TN) loss mainly occurred during the initial 12 days when the soil was flooded, then presented N immobilized by soil and finally, basically balanced between influent and effluent after 50 days.	Nitrogen	142-143	C-type lectin domain family 3 member B	Homo sapiens	48-50
35461100-3	2022	We demonstrate with the Chesapeake Bay Non-Tidal Monitoring Network that machine learning approaches - i.e., hierarchical clustering and random forest (RF) classification - can be combined to better understand the regional patterns and drivers of total nitrogen (TN) trends in large monitoring networks, resulting in information useful for watershed management.	Nitrogen	253-261	C-type lectin domain family 3 member B	Homo sapiens	263-265
35248853-1	2022	Rapidly and accurately detect the total nitrogen (TN) concentration is enormously important for surface water protection considering the critical role it plays in reflecting the eutrophication of surface water.	Nitrogen	40-48	C-type lectin domain family 3 member B	Homo sapiens	50-52
35614078-5	2022	The results showed that the average total Nr loss was 52.5 kg N ha-1 (range: 4.6-157.8 kg N ha-1), which accounts for 26.1% of the total N applied.	Nitrogen	137-138	solute carrier family 9 member B1	Homo sapiens	62-68
35614078-5	2022	The results showed that the average total Nr loss was 52.5 kg N ha-1 (range: 4.6-157.8 kg N ha-1), which accounts for 26.1% of the total N applied.	Nitrogen	137-138	solute carrier family 9 member B1	Homo sapiens	90-96
35629731-7	2022	Our study also confirmed that deprotonation preferentially occurred by desorbing the dihydrogen atom on nitrogen atoms during the carbonization of PPy.	Nitrogen	104-112	pancreatic polypeptide	Homo sapiens	147-150
35603929-2	2022	It is a mucin-degrading bacterium that can colonise intestines of mammals such as humans and mice by utilising mucin as the only nitrogen and carbon source.	Nitrogen	129-137	LOC100508689	Homo sapiens	8-13
35603929-2	2022	It is a mucin-degrading bacterium that can colonise intestines of mammals such as humans and mice by utilising mucin as the only nitrogen and carbon source.	Nitrogen	129-137	LOC100508689	Homo sapiens	111-116
35352423-2	2022	Subsequent treatment with base resulted in C-N bond formation to yield a mu 3 - eta 2 : eta 2 -1-azabutadien-4-yl complex, ((Cp*Ru) 3 ( mu 3 -CH)( mu 3 - eta 2 : eta 2 -NH=CH-CMe=CH-)) + ( 6a ).	Nitrogen	45-46	DNA polymerase iota	Homo sapiens	88-93
35352423-2	2022	Subsequent treatment with base resulted in C-N bond formation to yield a mu 3 - eta 2 : eta 2 -1-azabutadien-4-yl complex, ((Cp*Ru) 3 ( mu 3 -CH)( mu 3 - eta 2 : eta 2 -NH=CH-CMe=CH-)) + ( 6a ).	Nitrogen	45-46	DNA polymerase iota	Homo sapiens	162-167
35411903-2	2022	In this work, PAN-based blend precursors are investigated using ReaxFF reactive molecular dynamics simulations with respect to the formation of all-carbon rings, the evolutions of oxygen-containing and nitrogen-containing species, and the migration of carbon atoms to form turbostratic graphene.	Nitrogen	202-210	adenosine deaminase 2	Homo sapiens	14-17
35137667-6	2022	Treatment with 10 mug HSPB5 substantially reduced endocapillary proliferation and tubular atrophy, which significantly reduced proteinuria and blood urea nitrogen (BUN).	Nitrogen	154-162	crystallin, alpha B	Mus musculus	22-27
35124122-5	2022	The bulk N deposition rates decreased from 45.77 kg N ha-1 yr-1 in 2012 to 22.06 kg N ha-1 yr-1 in 2018, which could account for decrease of 1.01 mg N L-1 in the lake N concentrations via a rough estimation, and this value was close to the actual variation in N concentration in Lake Taihu.	Nitrogen	9-10	solute carrier family 9 member B1	Homo sapiens	52-63
35124122-5	2022	The bulk N deposition rates decreased from 45.77 kg N ha-1 yr-1 in 2012 to 22.06 kg N ha-1 yr-1 in 2018, which could account for decrease of 1.01 mg N L-1 in the lake N concentrations via a rough estimation, and this value was close to the actual variation in N concentration in Lake Taihu.	Nitrogen	9-10	solute carrier family 9 member B1	Homo sapiens	84-95
35124122-5	2022	The bulk N deposition rates decreased from 45.77 kg N ha-1 yr-1 in 2012 to 22.06 kg N ha-1 yr-1 in 2018, which could account for decrease of 1.01 mg N L-1 in the lake N concentrations via a rough estimation, and this value was close to the actual variation in N concentration in Lake Taihu.	Nitrogen	149-150	solute carrier family 9 member B1	Homo sapiens	84-95
35124122-5	2022	The bulk N deposition rates decreased from 45.77 kg N ha-1 yr-1 in 2012 to 22.06 kg N ha-1 yr-1 in 2018, which could account for decrease of 1.01 mg N L-1 in the lake N concentrations via a rough estimation, and this value was close to the actual variation in N concentration in Lake Taihu.	Nitrogen	167-168	solute carrier family 9 member B1	Homo sapiens	84-95
35124122-5	2022	The bulk N deposition rates decreased from 45.77 kg N ha-1 yr-1 in 2012 to 22.06 kg N ha-1 yr-1 in 2018, which could account for decrease of 1.01 mg N L-1 in the lake N concentrations via a rough estimation, and this value was close to the actual variation in N concentration in Lake Taihu.	Nitrogen	260-261	solute carrier family 9 member B1	Homo sapiens	84-95
35534729-3	2022	Ammonia activates the dissociation of glucose-regulated, N-glycosylated SREBP-cleavage-activating protein (SCAP) from insulin-inducible gene protein (Insig), an endoplasmic reticulum-retention protein, leading to SREBP translocation and lipogenic gene expression.	Nitrogen	57-58	SREBF chaperone	Homo sapiens	72-105
35534729-3	2022	Ammonia activates the dissociation of glucose-regulated, N-glycosylated SREBP-cleavage-activating protein (SCAP) from insulin-inducible gene protein (Insig), an endoplasmic reticulum-retention protein, leading to SREBP translocation and lipogenic gene expression.	Nitrogen	57-58	SREBF chaperone	Homo sapiens	107-111
35289411-4	2022	Herein, we carried out different types of DFT calculations, including EDA-NOCV analysis of the relevant cAAC-boron-dinitrogen complexes and their precursors, to shed light on the deeper insight of the bonding secret (EDA-NOCV = energy decomposition analysis coupled with natural orbital for chemical valence).	Nitrogen	115-125	ectodysplasin A	Homo sapiens	70-73
35289411-4	2022	Herein, we carried out different types of DFT calculations, including EDA-NOCV analysis of the relevant cAAC-boron-dinitrogen complexes and their precursors, to shed light on the deeper insight of the bonding secret (EDA-NOCV = energy decomposition analysis coupled with natural orbital for chemical valence).	Nitrogen	115-125	ectodysplasin A	Homo sapiens	217-220
35591511-9	2022	Additionally, N2 adsorption isotherm analysis demonstrates that the pore structure of these mixes has been densified as evidenced by a reduction in intruded volume and a rise in BET surface area.	Nitrogen	14-16	delta/notch like EGF repeat containing	Homo sapiens	178-181
35472010-6	2022	Suspended sediments (SS), total phosphorus (TP), and total nitrogen (TN) in EOF surface runoff varied over 3-5 orders.	Nitrogen	59-67	C-type lectin domain family 3 member B	Homo sapiens	69-71
35436090-3	2022	The dualism of N-dopants and binary metals lower the d-band centers of both Fe and Co in the Fe,Co,N-C catalyst, improving the overpotential of the overall electrocatalytic processes (DeltaEORR-OER = 0.74 +- 0.02 V vs RHE).	Nitrogen	99-101	factor interacting with PAPOLA and CPSF1	Homo sapiens	218-221
35427192-8	2022	These results demonstrate a previously unknown function of Atg1 in regulation of selective autophagy via Atg11 phosphorylation.Abbreviations: AMPK: AMP-activated protein kinase; ATG: autophagy-related; Cvt: cytoplasm-to-vacuole targeting; FUNDC1: FUN14 domain-containing protein 1; GFP: green fluorescent protein; MTOR: mechanistic target of rapamycin kinase; PAS: phagophore assembly site; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PRKAC/PKA: protein kinase cAMP-activated; SD-G: glucose starvation; SD-N: nitrogen starvation; ULK1: unc-51 like autophagy activating kinase 1; lambda-PPase: lambda protein phosphatase.	Nitrogen	529-537	unc-51 like autophagy activating kinase 1	Homo sapiens	59-63
35398972-4	2022	In this work, we attempted to shape the nano-topography of PEEK surface by nitrogen low-temperature plasma and polydopamine coating on the surface as a secondary reaction platform to bond the aminated poly (lactic-co-glycolic acid) (PLGA) microspheres encapsulating the BMP-2 gene for enhancing the biological activity.	Nitrogen	75-83	bone morphogenetic protein 2	Rattus norvegicus	270-275
35385928-4	2022	Breathing air with high concentrations of nitrogen dioxide and PM can result in over-expression of the angiotensin converting enzyme-2 (ACE-2) leading to stress of organs, such as heart and kidneys.	Nitrogen	42-50	angiotensin converting enzyme 2	Homo sapiens	103-134
35385928-4	2022	Breathing air with high concentrations of nitrogen dioxide and PM can result in over-expression of the angiotensin converting enzyme-2 (ACE-2) leading to stress of organs, such as heart and kidneys.	Nitrogen	42-50	angiotensin converting enzyme 2	Homo sapiens	136-141
35007660-6	2022	Interestingly, N-glycosylation of the CGRP receptor ECD was predicted to prevent MBP docking to the mutated peptide ligands.	Nitrogen	15-16	myelin basic protein	Homo sapiens	81-84
35007660-7	2022	I found that the N-glycosylation of CLR ECD N123 was the most critical for inhibiting MBP interaction with the mutated peptide ligands.	Nitrogen	17-18	myelin basic protein	Homo sapiens	86-89
17293438-8	2007	LHT1 mutants displayed impaired capacity for uptake of a range of amino acids from solutions, displayed impaired growth when N was supplied in organic forms, and acquired substantially lower amounts of amino acids than wild-type plants from solid growth media.	Nitrogen	125-126	lysine histidine transporter 1	Arabidopsis thaliana	0-4
35151689-8	2022	TGF-beta treatment primarily induced N-glycome aberrations involving elevated levels of branching, core fucosylation, and sialylation in PaTu-S cells, in agreement with TGF-beta-induced changes in the expression of glycosylation-associated genes.	Nitrogen	37-38	transforming growth factor alpha	Homo sapiens	0-8
35151689-8	2022	TGF-beta treatment primarily induced N-glycome aberrations involving elevated levels of branching, core fucosylation, and sialylation in PaTu-S cells, in agreement with TGF-beta-induced changes in the expression of glycosylation-associated genes.	Nitrogen	37-38	transforming growth factor alpha	Homo sapiens	169-177
35151689-10	2022	Furthermore, the expression of transcription factor SOX4 was upregulated upon TGF-beta stimulation, and its depletion blocked TGF-beta-induced N-glycomic changes.	Nitrogen	143-144	transforming growth factor alpha	Homo sapiens	78-86
35151689-10	2022	Furthermore, the expression of transcription factor SOX4 was upregulated upon TGF-beta stimulation, and its depletion blocked TGF-beta-induced N-glycomic changes.	Nitrogen	143-144	transforming growth factor alpha	Homo sapiens	126-134
35151689-11	2022	Thus, TGF-beta-induced N-glycosylation changes can occur in a SOX4-dependent and SMAD4-independent manner in the pancreatic PaTu-S cancer cell line.	Nitrogen	23-24	transforming growth factor alpha	Homo sapiens	6-14
35151689-11	2022	Thus, TGF-beta-induced N-glycosylation changes can occur in a SOX4-dependent and SMAD4-independent manner in the pancreatic PaTu-S cancer cell line.	Nitrogen	23-24	SMAD family member 4	Homo sapiens	81-86
35273585-12	2022	For acetate esters, the regulation occurred at gene level: the ATF2 gene was overexpressed following nitrogen addition during the stationary phase.	Nitrogen	101-109	alcohol O-acetyltransferase	Saccharomyces cerevisiae S288C	63-67
17315267-6	2007	We demonstrate that Ccw12p is highly N-glycosylated.	Nitrogen	37-38	Ccw12p	Saccharomyces cerevisiae S288C	20-26
35167422-0	2022	Bidirectional roles of the Ccr4-Not complex in regulating autophagy before and after nitrogen starvation.	Nitrogen	85-93	CCR4-NOT core exoribonuclease subunit CCR4	Saccharomyces cerevisiae S288C	27-31
17213275-10	2007	The gender (P = 0.03), blood urea nitrogen (P = 0.005), and triglycerides (P = 0.04) were significant and independent determinants of plasma PEDF levels in diabetic patients.	Nitrogen	34-42	serpin family F member 1	Homo sapiens	141-145
35123071-1	2022	Bisecting N-acetylglucosamine (GlcNAc), a GlcNAc linked to the core beta-mannose residue via a beta1,4 linkage, is a special type of N-glycosylated modification that has been reported to be involved in various biological processes, such as cell adhesion and fetal development.	Nitrogen	133-134	AA1	Homo sapiens	93-100
35088417-6	2022	IRF2 knockdown suppressed the levels of creatinine, blood urea nitrogen, and kidney injury molecule 1 and decreased the renal injury score in mice.	Nitrogen	63-71	interferon regulatory factor 2	Mus musculus	0-4
17172286-0	2007	Nitrogen-dependent posttranscriptional regulation of the ammonium transporter AtAMT1;1.	Nitrogen	0-8	ammonium transporter 1;1	Arabidopsis thaliana	78-86
35202131-5	2022	The model was built on STELLA, a dynamic modelling software, and is based on constitutive cell quota that varies with nitrogen, phosphorus, and temperature.	Nitrogen	118-126	developmental pluripotency associated 3	Homo sapiens	23-29
17172286-6	2007	Moreover, steady-state transcript levels were decreased after addition of ammonium or nitrate in N-deficient roots, suggesting a role for N availability in regulating AtAMT1;1 transcript abundance.	Nitrogen	97-98	ammonium transporter 1;1	Arabidopsis thaliana	167-175
35084690-0	2022	Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)n. Spinocerebellar ataxia type 31 (SCA31), an autosomal-dominant neurodegenerative disorder characterized by progressive cerebellar ataxia with Purkinje cell degeneration, is caused by a heterozygous 2.5-3.8 kilobase penta-nucleotide repeat of (TTCCA)n in intron 11 of the thymidine kinase 2 (TK2) gene.	Nitrogen	409-411	thymidine kinase 2	Homo sapiens	0-18
35084690-0	2022	Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)n. Spinocerebellar ataxia type 31 (SCA31), an autosomal-dominant neurodegenerative disorder characterized by progressive cerebellar ataxia with Purkinje cell degeneration, is caused by a heterozygous 2.5-3.8 kilobase penta-nucleotide repeat of (TTCCA)n in intron 11 of the thymidine kinase 2 (TK2) gene.	Nitrogen	409-411	thymidine kinase 2	Homo sapiens	432-450
35084690-0	2022	Thymidine Kinase 2 and Mitochondrial Protein COX I in the Cerebellum of Patients with Spinocerebellar Ataxia Type 31 Caused by Penta-nucleotide Repeats (TTCCA)n. Spinocerebellar ataxia type 31 (SCA31), an autosomal-dominant neurodegenerative disorder characterized by progressive cerebellar ataxia with Purkinje cell degeneration, is caused by a heterozygous 2.5-3.8 kilobase penta-nucleotide repeat of (TTCCA)n in intron 11 of the thymidine kinase 2 (TK2) gene.	Nitrogen	409-411	thymidine kinase 2	Homo sapiens	452-455
17172286-7	2007	Nitrogen deficiency-dependent accumulation of AtAMT1;1 mRNA was also observed in 35S:AtAMT1;1-transformed Arabidopsis shoots but not in roots.	Nitrogen	0-8	ammonium transporter 1;1	Arabidopsis thaliana	46-54
35425364-10	2022	EDA-NOCV analysis suggests that N2 is a stronger pi-acceptor rather than a sigma-donor.	Nitrogen	32-34	ectodysplasin A	Homo sapiens	0-3
17172286-7	2007	Nitrogen deficiency-dependent accumulation of AtAMT1;1 mRNA was also observed in 35S:AtAMT1;1-transformed Arabidopsis shoots but not in roots.	Nitrogen	0-8	ammonium transporter 1;1	Arabidopsis thaliana	85-93
18232232-4	2007	It restricted uptake and transport of NO3(-), inhibited activity of some key nitrogen-metabolism-related enzymes, such as: nitrate reductase (NR) to the nitrate reduction, glutamine systhetase (GS) and glutamine synthase (GOGAT) to the ammonia assimilation, while it increased the content of free amino acids and decreased that of soluble protein as well.	Nitrogen	77-85	inducible nitrate reductase [NADH] 1	Glycine max	123-140
35208294-1	2022	In this study, the breakdown behavior of a calibrated depletion mode AlGaN/GaN transistor with a nitrogen-implanted gate region was simulated and analyzed using Sentaurus TCAD simulation, with particular emphasis on the metal contact design rule for a GaN-based high-electron-mobility transistor (HEMT) device with a variety of 2DEG concentrations grown on a silicon substrate.	Nitrogen	97-105	gigaxonin	Homo sapiens	75-78
35208294-1	2022	In this study, the breakdown behavior of a calibrated depletion mode AlGaN/GaN transistor with a nitrogen-implanted gate region was simulated and analyzed using Sentaurus TCAD simulation, with particular emphasis on the metal contact design rule for a GaN-based high-electron-mobility transistor (HEMT) device with a variety of 2DEG concentrations grown on a silicon substrate.	Nitrogen	97-105	gigaxonin	Homo sapiens	252-255
18232232-4	2007	It restricted uptake and transport of NO3(-), inhibited activity of some key nitrogen-metabolism-related enzymes, such as: nitrate reductase (NR) to the nitrate reduction, glutamine systhetase (GS) and glutamine synthase (GOGAT) to the ammonia assimilation, while it increased the content of free amino acids and decreased that of soluble protein as well.	Nitrogen	77-85	inducible nitrate reductase [NADH] 1	Glycine max	142-144
35208294-6	2022	When the contact position was far away from the AlGaN/GaN, the breakdown voltage of the nitrogen-implanted gated device decreased by 41% because of the relatively low electron density and weak induced piezoelectric effect.	Nitrogen	88-96	gigaxonin	Homo sapiens	54-57
17078987-6	2006	Blood urea nitrogen levels were elevated by 2 h in Neu mice after doses of 7.5 micromol/kg (Neu vs C3H, 32.8+/-4.1 vs 17.9+/-0.3 mg/dl).	Nitrogen	11-19	neuraminidase 1	Mus musculus	51-54
35048218-6	2022	The total nitrogen (TN) output error was the most sensitive to land-use change, with a gradient of 0.73.	Nitrogen	10-18	C-type lectin domain family 3 member B	Homo sapiens	20-22
35045112-11	2022	Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition.	Nitrogen	96-97	glucan endo-1,3-beta-glucosidase, basic isoform	Malus domestica	8-13
35045112-11	2022	Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition.	Nitrogen	96-97	glucan endo-1,3-beta-glucosidase, basic isoform	Malus domestica	18-23
35045112-11	2022	Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition.	Nitrogen	116-117	glucan endo-1,3-beta-glucosidase, basic isoform	Malus domestica	8-13
35045112-11	2022	Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition.	Nitrogen	116-117	glucan endo-1,3-beta-glucosidase, basic isoform	Malus domestica	18-23
35045112-11	2022	Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition.	Nitrogen	170-171	glucan endo-1,3-beta-glucosidase, basic isoform	Malus domestica	8-13
35045112-11	2022	Both SS+Glu-2 and Glu-2 treatments significantly enhanced (P<0.05) the contents of nitrate (NO3-N) and nitrite (NO2-N), but sharply decreased (P<0.05) the ammonium (NH4+-N) content compared with no glucose addition.	Nitrogen	170-171	glucan endo-1,3-beta-glucosidase, basic isoform	Malus domestica	18-23
35055047-7	2022	These new findings suggest that COE2-dependent signaling not only coordinates gene expression but also promotes chloroplast development and function by modulating root development and absorption of nitrogen compounds.	Nitrogen	198-206	EBF transcription factor 2	Homo sapiens	32-36
17078987-6	2006	Blood urea nitrogen levels were elevated by 2 h in Neu mice after doses of 7.5 micromol/kg (Neu vs C3H, 32.8+/-4.1 vs 17.9+/-0.3 mg/dl).	Nitrogen	11-19	neuraminidase 1	Mus musculus	92-95
35057208-2	2022	The reaction mechanism found involves metalation of an N-H residue of the carbene ligand by the catalyst Ag2O and the formation of a key transition state showing a mu-eta2:eta2 coordination of the formamidinyl ligand between manganese and silver, which allows a translocation process of Mn(I) and silver(I) ions between the carbene carbon atom and the nitrogen atom, before the formation of the formamidine ligand is completed.	Nitrogen	352-360	DNA polymerase iota	Homo sapiens	167-171
35057208-2	2022	The reaction mechanism found involves metalation of an N-H residue of the carbene ligand by the catalyst Ag2O and the formation of a key transition state showing a mu-eta2:eta2 coordination of the formamidinyl ligand between manganese and silver, which allows a translocation process of Mn(I) and silver(I) ions between the carbene carbon atom and the nitrogen atom, before the formation of the formamidine ligand is completed.	Nitrogen	352-360	DNA polymerase iota	Homo sapiens	172-176
16887913-6	2006	Opioid receptor-like-1 (ORL-1) receptors were blocked by pretreatment with compound B (Comp B), a purported OFQ/N antagonist, or receptor synthesis was disrupted by pretreatment with ORL-1 receptor antisense oligonucleotides.	Nitrogen	112-113	opioid related nociceptin receptor 1	Rattus norvegicus	0-22
34974624-0	2022	UCP1 and AOX1a contribute to regulation of carbon and nitrogen metabolism and yield in Arabidopsis under low nitrogen stress.	Nitrogen	109-117	alternative oxidase 1A	Arabidopsis thaliana	9-14
34974624-4	2022	Low N markedly increased AOX1a and UCP1 expression, alternative pathway capacity and UCP activity.	Nitrogen	4-5	alternative oxidase 1A	Arabidopsis thaliana	25-30
34974624-5	2022	Eight-day-old aox1a/ucp1 seedlings were more sensitive to low N than Col-0 and single mutants, exhibiting lower primary root length and higher anthocyanin accumulation.	Nitrogen	62-63	alternative oxidase 1A	Arabidopsis thaliana	14-19
34974624-6	2022	The net photosynthetic rate, electron transport rate, PSII actual photochemical efficiency, stomatal conductance and carboxylation efficiency were markedly decreased in ucp1 and aox1a/ucp1 compared to those in Col-0 and aox1a under low N stress; comparatively, chlorophyll content and non-photochemical quenching coefficient were the lowest and highest in aox1a/ucp1, respectively.	Nitrogen	236-237	alternative oxidase 1A	Arabidopsis thaliana	178-183
34974624-8	2022	The C/N ratio in seeds, but not in leaves, is higher in aox1a/ucp1 than that in Col-0, aox1a and ucp1 under low N condition.	Nitrogen	6-7	alternative oxidase 1A	Arabidopsis thaliana	56-61
34974624-9	2022	RNA-seq analysis revealed that many genes involved in photosynthesis and C/N metabolism were markedly down-regulated in aox1a/ucp1 under low N stress.	Nitrogen	75-76	alternative oxidase 1A	Arabidopsis thaliana	120-125
34974624-9	2022	RNA-seq analysis revealed that many genes involved in photosynthesis and C/N metabolism were markedly down-regulated in aox1a/ucp1 under low N stress.	Nitrogen	141-142	alternative oxidase 1A	Arabidopsis thaliana	120-125
16887913-6	2006	Opioid receptor-like-1 (ORL-1) receptors were blocked by pretreatment with compound B (Comp B), a purported OFQ/N antagonist, or receptor synthesis was disrupted by pretreatment with ORL-1 receptor antisense oligonucleotides.	Nitrogen	112-113	opioid related nociceptin receptor 1	Rattus norvegicus	24-29
34974624-10	2022	These results highlight the key roles of UCP1 and AOX1a in modulating photosynthetic capacity, C/N assimilation and distribution under low N stress.	Nitrogen	97-98	alternative oxidase 1A	Arabidopsis thaliana	50-55
34974624-10	2022	These results highlight the key roles of UCP1 and AOX1a in modulating photosynthetic capacity, C/N assimilation and distribution under low N stress.	Nitrogen	139-140	alternative oxidase 1A	Arabidopsis thaliana	50-55
16887913-13	2006	Furthermore, OFQ/N plays a physiologically significant role in the regulation of prolactin secretion during lactation, and it mediates its effects via actions at the ORL-1 receptor subtype.	Nitrogen	17-18	opioid related nociceptin receptor 1	Rattus norvegicus	166-171
17023392-0	2006	N-linked glycosylation of IL-13R alpha2 is essential for optimal IL-13 inhibitory activity.	Nitrogen	0-1	interleukin 13 receptor subunit alpha 2	Homo sapiens	26-39
17026539-5	2006	In transgenic lines carrying AMT-promoter-GFP constructs, the promoter activities of AMT1;1 and AMT1;3 were both upregulated under nitrogen-deficiency conditions and were localized to the rhizodermis, including root hairs.	Nitrogen	131-139	ammonium transporter 1;1	Arabidopsis thaliana	85-91
34636707-5	2022	Transient overexpression of myc-tagged Prss53 in COS-7 cells showed that Prss53 was strongly associated with the luminal surfaces of organellar membranes and that it underwent signal peptide cleavage and N-glycosylation.	Nitrogen	204-205	protease, serine 53	Mus musculus	39-45
34636707-5	2022	Transient overexpression of myc-tagged Prss53 in COS-7 cells showed that Prss53 was strongly associated with the luminal surfaces of organellar membranes and that it underwent signal peptide cleavage and N-glycosylation.	Nitrogen	204-205	protease, serine 53	Mus musculus	73-79
17026539-5	2006	In transgenic lines carrying AMT-promoter-GFP constructs, the promoter activities of AMT1;1 and AMT1;3 were both upregulated under nitrogen-deficiency conditions and were localized to the rhizodermis, including root hairs.	Nitrogen	131-139	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	85-89
34967426-9	2022	We were determined that the vast majority of patients with perforated appendicitis were male; had more frequent chronic kidney disease and post-operative local complications; had increased leukocytes, neutrophils, blood urea nitrogen, creatinine, and total bilirubin; and had reduced albumin; and these differences were statistically significant (all values p<0.05).	Nitrogen	225-233	3-hydroxyanthranilate 3,4-dioxygenase	Homo sapiens	175-178
17026539-8	2006	These results suggest an additive contribution of AMT1;1 and AMT1;3 to the overall ammonium uptake capacity in Arabidopsis roots under nitrogen-deficiency conditions.	Nitrogen	135-143	ammonium transporter 1;1	Arabidopsis thaliana	50-56
17026539-8	2006	These results suggest an additive contribution of AMT1;1 and AMT1;3 to the overall ammonium uptake capacity in Arabidopsis roots under nitrogen-deficiency conditions.	Nitrogen	135-143	anthranilate synthase alpha subunit 1	Arabidopsis thaliana	50-54
17029381-5	2006	The solid-state structures of the new complexes show variable asymmetry in the potassium-nitrogen distances within the eta2-interactions and also show variable bending of the heterocyclic C2N3 and CN4 cores toward the best plane of the 18-crown-6 ligand oxygen atoms.	Nitrogen	89-97	DNA polymerase iota	Homo sapiens	119-123
16899466-10	2006	The mouse MT-CYP1A1 is an extrinsic membrane protein, which exhibited high FDX1 plus FDXR-mediated N-demethylation of a number of tricyclic antidepressants, pain killers, anti-psychotics, and narcotics that are poor substrates for microsomal CYP1A1.	Nitrogen	99-100	ferredoxin reductase	Mus musculus	85-89
16938437-0	2006	N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53.	Nitrogen	0-1	nicastrin	Homo sapiens	25-34
16938437-0	2006	N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53.	Nitrogen	0-1	calnexin	Homo sapiens	107-115
16938437-0	2006	N-glycosylation of human nicastrin is required for interaction with the lectins from the secretory pathway calnexin and ERGIC-53.	Nitrogen	0-1	lectin, mannose binding 1	Homo sapiens	120-128
16938437-7	2006	All hNCT mutants interacted with calnexin and ERGIC-53, indicating that the association was not mediated by any single N-glycosylation site.	Nitrogen	5-6	calnexin	Homo sapiens	33-41
16938437-7	2006	All hNCT mutants interacted with calnexin and ERGIC-53, indicating that the association was not mediated by any single N-glycosylation site.	Nitrogen	5-6	lectin, mannose binding 1	Homo sapiens	46-54
16547752-2	2006	Fifteen variants of HIV-1 isolate NL4-3 with mutations of the six N-glycosylation sites g2-g7 within the V1 (g2-g4) and V2 loop (g5-g7) of gp120 were analyzed for viral infectivity and their sensitivity to neutralization.	Nitrogen	34-35	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	139-144
16682414-0	2006	N-glycosylation affects the molecular organization and stability of E-cadherin junctions.	Nitrogen	0-1	cadherin 1	Canis lupus familiaris	68-78
16682414-5	2006	This suggested that variations in AJ stability were accompanied by quantitative and qualitative changes in E-cadherin N-glycosylation.	Nitrogen	118-119	cadherin 1	Canis lupus familiaris	107-117
16698089-9	2006	Altered L/N ratios, in particular decreases of CD45, were mainly observed in precursor neoplasms and in T-cell neoplasms.	Nitrogen	10-11	protein tyrosine phosphatase receptor type C	Canis lupus familiaris	47-51
16861926-0	2006	Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species.	Nitrogen	0-8	H2A.X variant histone	Homo sapiens	49-53
16720684-5	2006	Expressed rat UGT1.1, UGT2B1, and UGT2B12 in HK293 cells catalyzed the N-glucuronidation of FOSA but at rates that were lower than those observed in rat liver microsomes.	Nitrogen	71-72	UDP glucuronosyltransferase family 1 member A1	Rattus norvegicus	14-20
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	72-73	UDP glucuronosyltransferase family 1 member A1	Rattus norvegicus	31-37
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	162-163	UDP glucuronosyltransferase family 1 member A1	Rattus norvegicus	31-37
16514542-11	2006	Moreover, growth on glucose induced genes for nitrogen remobilisation that are typically enhanced during developmental senescence, including the glutamine synthetase gene GLN1;4 and the nitrate transporter gene AtNRT2.5.	Nitrogen	46-54	glutamine synthetase 1;4	Arabidopsis thaliana	171-177
16514542-11	2006	Moreover, growth on glucose induced genes for nitrogen remobilisation that are typically enhanced during developmental senescence, including the glutamine synthetase gene GLN1;4 and the nitrate transporter gene AtNRT2.5.	Nitrogen	46-54	nitrate transporter2.5	Arabidopsis thaliana	211-219
16816136-5	2006	Seedlings deficient in LHT1 cannot use Glu or Asp as sole nitrogen sources because of the severe inhibition of amino acid uptake from the medium, and uptake of amino acids into mesophyll protoplasts is inhibited.	Nitrogen	58-66	lysine histidine transporter 1	Arabidopsis thaliana	23-27
16816136-8	2006	The capacity for amino acid uptake, and thus nitrogen use efficiency under limited inorganic N supply, is increased severalfold by LHT1 overexpression.	Nitrogen	45-53	lysine histidine transporter 1	Arabidopsis thaliana	131-135
16816136-9	2006	These results suggest that LHT1 overexpression may improve the N efficiency of plant growth under limiting nitrogen, and the mutant analyses may enhance our understanding of N cycling in plants.	Nitrogen	107-115	lysine histidine transporter 1	Arabidopsis thaliana	27-31
16751196-8	2006	Comparisons are made with similar studies done with human pols eta and iota; pol kappa is the most resistant to N(2)-bulk and the most quantitatively efficient of these in catalyzing dCTP incorporation opposite bulky guanine N(2)-adducts, particularly the largest (N(2)-BPG).	Nitrogen	112-116	endothelin receptor type A	Homo sapiens	63-66
16585136-0	2006	N-Glycosylation of the MUC1 mucin in epithelial cells and secretions.	Nitrogen	0-1	mucin 1, cell surface associated	Homo sapiens	23-27
16585136-0	2006	N-Glycosylation of the MUC1 mucin in epithelial cells and secretions.	Nitrogen	0-1	LOC100508689	Homo sapiens	28-33
16585136-4	2006	Here, we evaluated the N-glycosylation of MUC1 derived from two sources: endogenous MUC1 isolated from human milk and a recombinant epitope-tagged MUC1F overexpressed in Caco2 colon carcinoma cells.	Nitrogen	23-24	mucin 1, cell surface associated	Homo sapiens	42-46
16817772-1	2006	In order to assess the effect of the N-glycans associated with the GP5 neutralization epitope of porcine reproductive and respiratory syndrome virus (PRRSV) on the neutralizing antibody (Ab) response of swine, groups of young pigs were infected with PRRSV strains differing in N-glycosylation pattern.	Nitrogen	37-38	glycoprotein V platelet	Sus scrofa	67-70
16601122-7	2006	These interactions were verified in GST-pull down assays in which human SHBG bound the carboxyl-terminal domains of fibulin-1D and fibulin-2 in a steroid-dependent manner, with estradiol being the most effective ligand, and were enhanced by reducing the N-glycosylation of human SHBG.	Nitrogen	254-255	fibulin 2	Homo sapiens	131-140
16510538-6	2006	In in vitro studies, rates of formation of N-alkylPP in liver and lung microsomes incubated with DASO2 and NADPH were dependent on time and protein concentrations, but were negligible in control incubations performed in the absence of NADPH or DASO2 or with boiled microsomes.	Nitrogen	43-44	2,4-dienoyl CoA reductase 1, mitochondrial	Mus musculus	107-112
16510538-6	2006	In in vitro studies, rates of formation of N-alkylPP in liver and lung microsomes incubated with DASO2 and NADPH were dependent on time and protein concentrations, but were negligible in control incubations performed in the absence of NADPH or DASO2 or with boiled microsomes.	Nitrogen	43-44	2,4-dienoyl CoA reductase 1, mitochondrial	Mus musculus	235-240
16713180-6	2006	Feeding an n-3 PUFA diet to rats with DP upregulated IL-10 mRNA in the pancreas and IL-4 and IL-10 mRNA in the spleen.	Nitrogen	5-6	interleukin 4	Rattus norvegicus	84-88
16792405-0	2006	Nitrogen-containing phorbol esters from Croton ciliatoglandulifer and their effects on cyclooxygenases-1 and -2.	Nitrogen	0-8	prostaglandin-endoperoxide synthase 2	Mus musculus	87-111
16722709-1	2006	Near-infrared spectroscopy was used to monitor HO2 formed by pulsed laser photolysis of Cl2-O2-CH3OH-N2 mixtures.	Nitrogen	101-103	heme oxygenase 2	Homo sapiens	47-50
16641243-2	2006	The lysosomal vesicle-associated soluble N-ethylmaleimide-sensitive factor attachment protein receptor tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP)/VAMP7 was previously implicated in membrane fusion events mediating neurite outgrowth, but the participation of lysosomes in this exocytic process has remained unclear.	Nitrogen	41-42	vesicle-associated membrane protein 7	Mus musculus	171-178
16641243-2	2006	The lysosomal vesicle-associated soluble N-ethylmaleimide-sensitive factor attachment protein receptor tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP)/VAMP7 was previously implicated in membrane fusion events mediating neurite outgrowth, but the participation of lysosomes in this exocytic process has remained unclear.	Nitrogen	41-42	vesicle-associated membrane protein 7	Mus musculus	180-185
16533755-7	2006	Cells treated with tunicamycin, an inhibitor of glycosylation, prevented TLR3-induced NF-kappaB activation, confirming that N-linked glycosylation is required for bioactivity of this receptor.	Nitrogen	86-87	toll like receptor 3	Homo sapiens	73-77
16613455-12	2006	A predictor-corrector method of the fifth order (PC5) was found to be efficient and precise and was therefore adopted for the simulation of the molecular nitrogen properties at high pressure.	Nitrogen	154-162	proprotein convertase subtilisin/kexin type 5	Homo sapiens	49-52
16597953-6	2006	These results indicate that the conversion of N(2)O to N(2) depends exclusively on the respiratory N(2)O reductase and that soybean roots nodulated with B. japonicum carrying the nos genes are able to remove very low concentrations of N(2)O.	Nitrogen	46-50	chalcone reductase CHR1	Glycine max	105-114
16337118-1	2006	Exploiting the SAR of the known pyrrole derivatives, a new class of mGluR1 antagonists was developed through a cyclization of the C-2 position on the pyrrole N-1 nitrogen.	Nitrogen	162-170	glutamate metabotropic receptor 1	Homo sapiens	68-74
16531813-9	2006	The data demonstrate the influence of the N-glycosylation pattern on the ADCC activity of chimeric CD19 antibodies and point to the importance of suitable expression systems for the production of highly active therapeutic antibodies.	Nitrogen	42-43	CD19 molecule	Homo sapiens	99-103
16553884-5	2006	Accordingly, when yeast is grown on a low-quality nitrogen source, or under amino acid deprivation, the expression of both UGA3 and GLT1 is induced through the action of both these global transcriptional modulators that bind to a region of the bidirectional promoter.	Nitrogen	50-58	Uga3p	Saccharomyces cerevisiae S288C	123-127
16553884-5	2006	Accordingly, when yeast is grown on a low-quality nitrogen source, or under amino acid deprivation, the expression of both UGA3 and GLT1 is induced through the action of both these global transcriptional modulators that bind to a region of the bidirectional promoter.	Nitrogen	50-58	glutamate synthase (NADH)	Saccharomyces cerevisiae S288C	132-136
16799704-2	2006	We have investigated the effect of nitrogen protecting groups in radical addition trapping experiments leading to beta(2)-amino acids.	Nitrogen	35-43	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	114-120
16360109-3	2006	Oligosaccharide structures in a humanized anti-Abeta IgG1 monoclonal antibody (Mab) with an N-glycosylation site in the complementary determining region (CDR2) of the heavy chain variable region were elucidated by LC/MS analysis following sequential exoglycosidase treatments of the endoproteinase Lys-C digest.	Nitrogen	92-93	cerebellar degeneration related protein 2	Homo sapiens	154-158
16467158-6	2006	We show that the double N-methylated full length IAPP analog [(N-Me)G24, (N-Me)I26]-IAPP (IAPP-GI) is a highly soluble, nonamyloidogenic, and noncytotoxic IAPP molecular mimic and an IAPP receptor agonist.	Nitrogen	24-25	islet amyloid polypeptide	Homo sapiens	49-53
16467158-6	2006	We show that the double N-methylated full length IAPP analog [(N-Me)G24, (N-Me)I26]-IAPP (IAPP-GI) is a highly soluble, nonamyloidogenic, and noncytotoxic IAPP molecular mimic and an IAPP receptor agonist.	Nitrogen	24-25	islet amyloid polypeptide	Homo sapiens	84-88
16467158-6	2006	We show that the double N-methylated full length IAPP analog [(N-Me)G24, (N-Me)I26]-IAPP (IAPP-GI) is a highly soluble, nonamyloidogenic, and noncytotoxic IAPP molecular mimic and an IAPP receptor agonist.	Nitrogen	24-25	islet amyloid polypeptide	Homo sapiens	84-88
16467158-6	2006	We show that the double N-methylated full length IAPP analog [(N-Me)G24, (N-Me)I26]-IAPP (IAPP-GI) is a highly soluble, nonamyloidogenic, and noncytotoxic IAPP molecular mimic and an IAPP receptor agonist.	Nitrogen	24-25	islet amyloid polypeptide	Homo sapiens	84-88
16467158-6	2006	We show that the double N-methylated full length IAPP analog [(N-Me)G24, (N-Me)I26]-IAPP (IAPP-GI) is a highly soluble, nonamyloidogenic, and noncytotoxic IAPP molecular mimic and an IAPP receptor agonist.	Nitrogen	24-25	islet amyloid polypeptide	Homo sapiens	84-88
16221666-6	2006	We show here that PSMA is not only heavily N-but also O-glycosylated.	Nitrogen	43-44	putative N-acetylated-alpha-linked acidic dipeptidase	Canis lupus familiaris	18-22
16221666-8	2006	Neither the cell-surface expression of PSMA nor its efficient apical sorting in polarized Madin-Darby canine kidney cells are influenced by modulators of N- and O-glycosylation.	Nitrogen	0-1	putative N-acetylated-alpha-linked acidic dipeptidase	Canis lupus familiaris	39-43
16169899-1	2006	In the noninflamed lung, surfactant protein A (SP-A) acts as an anti-inflammatory molecule through its effects on macrophage (MPhi) function, modulating cytokine and reactive oxygen and nitrogen intermediate production.	Nitrogen	186-194	surfactant protein A1	Homo sapiens	25-45
16169899-1	2006	In the noninflamed lung, surfactant protein A (SP-A) acts as an anti-inflammatory molecule through its effects on macrophage (MPhi) function, modulating cytokine and reactive oxygen and nitrogen intermediate production.	Nitrogen	186-194	surfactant protein A1	Homo sapiens	47-51
16214851-2	2006	Various bioactivating enzymes, such as cytochromes P450 and myeloperoxidase, have been shown to be capable of catalyzing the N-oxidation of these compounds.	Nitrogen	125-126	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	51-75
16365930-0	2006	Relationship between malt qualities and beta-amylase activity and protein content as affected by timing of nitrogen fertilizer application.	Nitrogen	107-115	1,4-alpha-D-glucan maltohydrolase	Hordeum vulgare	40-52
16336970-4	2005	Mrg19 is a putative transcription factor that regulates carbon and nitrogen metabolism in yeast.	Nitrogen	67-75	Csr2p	Saccharomyces cerevisiae S288C	0-5
16256074-0	2005	Caenorhabditis elegans calnexin is N-glycosylated and required for stress response.	Nitrogen	35-36	Calnexin	Caenorhabditis elegans	23-31
15926890-4	2005	All combined, our results show a differential functional impact of N-glycosylation on C2GnT-1 and FucT-VII and disclose that a strongly reduced FucT-VII activity retains the ability to fucosylate PSGL-1 on the core2-based binding site(s) for the three selectins.	Nitrogen	67-68	glucosaminyl (N-acetyl) transferase 1	Homo sapiens	86-93
16118201-8	2005	However, truncations of the N-glycosylated, lumenal domain of Pom152p and pom152 mutants lacking N-linked glycosylation sites are viable in combination with nup1Delta, suppress nup1Delta temperature sensitivity, and partially suppress the nuclear protein import defects associated with the deletion of NUP1.	Nitrogen	28-29	FG-nucleoporin NUP1	Saccharomyces cerevisiae S288C	302-306
16212347-1	2005	The reaction of ZnMe2 and the N-substituted phosphoramidic monoester [Et2NH2][(EtO)PO2(C6H5NH)] produces the trinuclear zinc cluster Zn(3)(Et2O)2[(EtO)PO2(C6H5NH)]6.2THF, demonstrating that the P-N bond can survive under mild solvothermal reaction conditions.	Nitrogen	30-31	RUNX1 partner transcriptional co-repressor 1	Homo sapiens	79-82
16212347-1	2005	The reaction of ZnMe2 and the N-substituted phosphoramidic monoester [Et2NH2][(EtO)PO2(C6H5NH)] produces the trinuclear zinc cluster Zn(3)(Et2O)2[(EtO)PO2(C6H5NH)]6.2THF, demonstrating that the P-N bond can survive under mild solvothermal reaction conditions.	Nitrogen	30-31	RUNX1 partner transcriptional co-repressor 1	Homo sapiens	147-150
15948716-5	2005	Nutritional analysis of the nce103 null mutant demonstrated that growth on glucose under a non-CO2-enriched nitrogen atmosphere was possible when the culture medium was provided with L-aspartate, fatty acids, uracil and L-argininine.	Nitrogen	108-116	carbonate dehydratase NCE103	Saccharomyces cerevisiae S288C	28-34
16190753-7	2005	Direct hydrogen bonding of the cyano nitrogen of the 5-cyanopyrimidine core to the backbone NH of Met109 was confirmed by X-ray crystallographic analysis of 3a bound to p38alpha.	Nitrogen	37-45	mitogen-activated protein kinase 14	Mus musculus	169-177
2598935-13	1989	H2O2-dependent N-demethylation of benzphetamine and aniline p-hydroxylation by cytochrome P-450 LM2 did not depend on its state of aggregation.	Nitrogen	15-16	cytochrome P450 2B4	Oryctolagus cuniculus	79-99
2590192-3	1989	The major portion of LGP 96 resides on the luminal side of the lysosome and bears a large number of N-linked heavily sialylated complex type carbohydrate chains, giving the mature molecule of 96 kDa.	Nitrogen	100-101	lysosomal-associated membrane protein 2	Rattus norvegicus	21-27
2586490-5	1989	When a homologous series of 5,8-dideazafolic acid analogs with hydrocarbon substituents on the 10-nitrogen were studied, these substituents were found to diminish the efficiency of utilization of these analogs as substrates for FPGS; this effect increased with increasing chain length of the hydrocarbon.	Nitrogen	98-106	folylpolyglutamyl synthetase	Mus musculus	228-232
2618084-8	1989	techniques (ROESY and HETCOR), showed the metabolite to be a quaternary ammonium glucuronide of croconazole: i.e. a chemical bond exists between a nitrogen, having sp2 type orbital, in the imidazole ring of croconazole and the anomeric carbon of glucuronic acid.	Nitrogen	147-155	LOW QUALITY PROTEIN: transcription factor Sp2	Oryctolagus cuniculus	164-167
2768245-5	1989	The deduced amino acid sequence is 80% homologous to a bovine soluble FBP, is greater than 99% homologous to the reported partial amino acid sequence of the human soluble FBP, contains three potential N-linked glycosylation sites, and has hydrophobic amino- and carboxylterminal regions which are consistent with a signal peptide and a potential membrane-anchoring domain, respectively.	Nitrogen	201-202	folate receptor alpha	Homo sapiens	171-174
2788137-1	1989	Continuous infusion of murine recombinant interleukin-1 alpha (rIL-1 alpha) into rats by using intraperitoneally implanted osmotic pumps led to marked decreases in body weight, liver enzymes (serum glutamic oxalacetic transaminase, serum glutamic pyruvic transaminase, and sorbitol dehydrogenase), appetite, and mobility and increases in drinking, blood urea nitrogen, and total peripheral blood leukocytes within 3 days.	Nitrogen	359-367	interleukin 1 alpha	Mus musculus	42-61
2742599-0	1989	Identification of a glutathione S-transferase associated with microsomes of tumor cells resistant to nitrogen mustards.	Nitrogen	101-109	hematopoietic prostaglandin D synthase	Rattus norvegicus	20-45
2671661-2	1989	The pso4-1 mutant strain was found to be completely blocked in mitotic recombination induced by photoaddition of mono- and bifunctional psoralen derivatives as well as by mono- (HN1) and bifunctional (HN2) nitrogen mustards or 254 nm UV radiation in both stationary and exponential phases of growth.	Nitrogen	206-214	E3 ubiquitin-protein ligase PRP19	Saccharomyces cerevisiae S288C	4-8
2653828-1	1989	In Saccharomyces cerevisiae, the pathway of 4-aminobutyric acid catabolism, for use as a nitrogen source, involves a specific permease (encoded by the UGA4 gene) and two enzymes (encoded by the UGA1 and UGA2 genes, respectively).	Nitrogen	89-97	Uga4p	Saccharomyces cerevisiae S288C	151-155
2709381-6	1989	The stereospecific attachment of all three alpha-halogenoses appears to occur by a Walden inversion (SN2 mechanism) at the C-1 carbon of the halogenose by the anionic N-1 of pyrazolo[3,4-b]pyridine.	Nitrogen	102-103	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	123-126
2471192-10	1989	We conclude: (i) The N-glycosylated subunits of the 200-kDa complex reflect the IGF I status.	Nitrogen	21-22	insulin-like growth factor 1	Rattus norvegicus	80-85
2748704-3	1989	Some thiazole derivatives, most of them containing nitrogen attached to the thiazole C-2 (19-20), were prepared from 17 and 18 by known method.	Nitrogen	51-59	complement C2	Homo sapiens	85-88
2466295-0	1989	An alternatively spliced region of the human hexabrachion contains a repeat of potential N-glycosylation sites.	Nitrogen	89-90	tenascin C	Gallus gallus	45-57
2545067-4	1989	These results suggest that N-linked sugars of the erythropoietin receptor protein are involved in the interaction of erythropoietin with the cell-surface receptors on B8 cells.	Nitrogen	27-28	erythropoietin	Mus musculus	50-64
2545067-4	1989	These results suggest that N-linked sugars of the erythropoietin receptor protein are involved in the interaction of erythropoietin with the cell-surface receptors on B8 cells.	Nitrogen	27-28	erythropoietin	Mus musculus	117-131
2695245-5	1989	All the TcR chains have similar protein structures consisting of extracellular variable and constant domains, intracellular cytoplasmic tails, and a hydrophobic transmembrane region with several potential N-linked glycosylation sites.	Nitrogen	205-206	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	8-11
2810434-3	1989	Competition of unlabelled N-VLDL and LDL with 125I-N-VLDL in fibroblasts suggested that LDL receptor may be involved in this process.	Nitrogen	26-27	low density lipoprotein receptor	Homo sapiens	88-100
2668660-5	1989	Therapeutic efficacy of N-MGP salt was confirmed in separate experiments where mice were infected intraperitoneally with unlabelled Candida albicans cells.	Nitrogen	24-25	matrix Gla protein	Mus musculus	26-29
3415241-9	1988	P-450 UT-2 (P-450h) had high aminopyrine N-demethylation and hydroxylation activities, but P-450 F-2 (P-450i) had low N-demethylation activity and no hydroxylation activities, but P-450 F-2 (P-450i) had low N-demethylation activity and no hydroxylation activity.	Nitrogen	41-42	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	6-10
3415241-9	1988	P-450 UT-2 (P-450h) had high aminopyrine N-demethylation and hydroxylation activities, but P-450 F-2 (P-450i) had low N-demethylation activity and no hydroxylation activities, but P-450 F-2 (P-450i) had low N-demethylation activity and no hydroxylation activity.	Nitrogen	41-42	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	12-19
2841185-5	1988	CHA1 is probably the structural gene for the enzyme; it is an abundant RNA in cells grown with serine and threonine as nitrogen source, whereas it is not detected when cells are grown on ammonium or proline, i.e., the transcription of the CHA1 gene is induced by serine or threonine.	Nitrogen	119-127	L-serine/L-threonine ammonia-lyase CHA1	Saccharomyces cerevisiae S288C	0-4
3418713-5	1988	When the free energies of (1), (2) and (4) are combined, one finds that the free energy of transferring the C=O ... H-N group from water to CCl4 is a surprising -1.4 kcal/mol (1 cal = 4.184 J).	Nitrogen	118-119	C-C motif chemokine ligand 4	Homo sapiens	140-144
3418713-8	1988	When appropriate methyl group transfer free energies are used, one finds that the free energy of transferring the C=O ... H-N group from water to CCl4 is +0.62 kcal/mol.	Nitrogen	124-125	C-C motif chemokine ligand 4	Homo sapiens	146-150
3366771-0	1988	N-linked glycosylation of a proenkephalin A-derived peptide.	Nitrogen	0-1	proenkephalin	Bos taurus	28-43
3366771-11	1988	These results show that an NH2 terminally extended Met-enkephalin Arg6-Gly7-Leu8 variant was N-glycosylated, and hence indicate that the precursor polypeptide proenkephalin A can be glycosylated during translation in the rough endoplasmic reticulum.	Nitrogen	27-28	proenkephalin	Bos taurus	159-174
2966060-8	1988	The significance of differences in N-linked glycosylation between the brain receptors for insulin and IGF-I and the corresponding receptors in liver is not known.	Nitrogen	35-36	insulin-like growth factor 1	Rattus norvegicus	102-107
16353914-4	2005	Structure-activity relationships in our own series of dihydroindolinone-based NOP ligands and those of the various reported ligands indicate that the lipophilic substituent on the common basic nitrogen present in all NOP ligands plays a role in determining the agonist/antagonist profile of the NOP ligand.	Nitrogen	193-201	opioid related nociceptin receptor 1	Homo sapiens	78-81
2967760-5	1988	The transmembrane orientation of the TcR chains and of CD 3 gamma and CD 3 delta can be directly inferred from their primary structure, based on the presence of concensus N-linked glycosylation sites N-terminal of their transmembrane domains.	Nitrogen	171-172	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	37-40
2967765-2	1988	We observed a requirement for N-linked glycosylation in the proper assembly and surface expression of HLA-B locus products in particular, although considerable variation was seen within the allelic series of the HLA-A and B loci.	Nitrogen	30-31	major histocompatibility complex, class I, B	Homo sapiens	102-107
16353914-4	2005	Structure-activity relationships in our own series of dihydroindolinone-based NOP ligands and those of the various reported ligands indicate that the lipophilic substituent on the common basic nitrogen present in all NOP ligands plays a role in determining the agonist/antagonist profile of the NOP ligand.	Nitrogen	193-201	opioid related nociceptin receptor 1	Homo sapiens	217-220
16353914-4	2005	Structure-activity relationships in our own series of dihydroindolinone-based NOP ligands and those of the various reported ligands indicate that the lipophilic substituent on the common basic nitrogen present in all NOP ligands plays a role in determining the agonist/antagonist profile of the NOP ligand.	Nitrogen	193-201	opioid related nociceptin receptor 1	Homo sapiens	217-220
16245837-4	2005	Overall, the PAH stability scale generated in this study agrees with those produced experimentally for ozone and nitrogen dioxides or developed using other in situ measurement techniques.	Nitrogen	113-121	phenylalanine hydroxylase	Homo sapiens	13-16
3397413-4	1988	Injection of somatotropin lowered blood urea nitrogen, increased plasma free fatty acids, and increased plasma somatotropin.	Nitrogen	45-53	somatotropin	Bos taurus	13-25
3283143-7	1988	One potential N-glycosylation site is found in the 18.8-kD (Sec 11p) predicted protein.	Nitrogen	14-15	signal peptidase complex catalytic subunit SEC11	Saccharomyces cerevisiae S288C	60-67
16164569-2	2005	To elucidate the physiological role of the nitrogen-metabolic PTS, we carried out phenotype microarray (PM) analysis with Escherichia coli K-12 strain MG1655 deleted for the ptsP gene encoding the first enzyme of the nitrogen-metabolic PTS.	Nitrogen	43-51	phosphoenolpyruvate-protein phosphotransferase PtsP	Escherichia coli str. K-12 substr. MG1655	174-178
2831375-4	1988	One of the gag-pol and env clones (GP+E-86) was able to transfer G418 resistance to recipient cells at a titer of as high as 1.7 X 10(5) when it was used to package delta neo and as high as 4 X 10(6) when it was used to package N2.	Nitrogen	228-230	Pr65	Moloney murine leukemia virus	11-14
16164569-2	2005	To elucidate the physiological role of the nitrogen-metabolic PTS, we carried out phenotype microarray (PM) analysis with Escherichia coli K-12 strain MG1655 deleted for the ptsP gene encoding the first enzyme of the nitrogen-metabolic PTS.	Nitrogen	217-225	phosphoenolpyruvate-protein phosphotransferase PtsP	Escherichia coli str. K-12 substr. MG1655	174-178
16180102-5	2005	TGF-beta1 increases the binding of laminin gamma1 to WGA-agarose and the binding is abolished by tunicamycin suggesting that laminin gamma1 is modified by N-linked glycosylation.	Nitrogen	155-156	transforming growth factor, beta 1	Mus musculus	0-9
3367907-7	1988	Unglycosylated NB, expressed either in influenza B virus-infected cells treated with tunicamycin or in cells expressing the NB mutant lacking both N-linked glycosylation sites, was expressed at the cell surface, indicating that NB does not require carbohydrate addition for transport.	Nitrogen	15-16	NUBP iron-sulfur cluster assembly factor 1, cytosolic	Homo sapiens	124-126
3367907-7	1988	Unglycosylated NB, expressed either in influenza B virus-infected cells treated with tunicamycin or in cells expressing the NB mutant lacking both N-linked glycosylation sites, was expressed at the cell surface, indicating that NB does not require carbohydrate addition for transport.	Nitrogen	15-16	NUBP iron-sulfur cluster assembly factor 1, cytosolic	Homo sapiens	124-126
16180102-5	2005	TGF-beta1 increases the binding of laminin gamma1 to WGA-agarose and the binding is abolished by tunicamycin suggesting that laminin gamma1 is modified by N-linked glycosylation.	Nitrogen	155-156	laminin, gamma 1	Mus musculus	35-49
16180102-5	2005	TGF-beta1 increases the binding of laminin gamma1 to WGA-agarose and the binding is abolished by tunicamycin suggesting that laminin gamma1 is modified by N-linked glycosylation.	Nitrogen	155-156	laminin, gamma 1	Mus musculus	125-139
16082728-4	2005	VAP-1 monomer has six potential N-linked, and three putative O-linked glycosylation sites and an SSSS sequence potentially forming an attachment site for an adjacent O-linked site.	Nitrogen	32-33	amine oxidase copper containing 3	Homo sapiens	0-5
2892826-0	1988	Regulation of nitrogen assimilation in Saccharomyces cerevisiae: roles of the URE2 and GLN3 genes.	Nitrogen	14-22	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	87-91
3121434-2	1987	In the put3-75 mutant, the basal level of expression (ammonia as nitrogen source) of PUT1-lacZ and PUT2-lacZ gene fusions as measured by beta-galactosidase activity is reduced 4- and 7-fold, respectively, compared with the wild-type strain.	Nitrogen	65-73	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	99-103
16082728-7	2005	Furthermore, mutation of the N-linked attachment sites strategically located on the top of the molecule reduces lymphocyte adhesion in non-static conditions, and enhances the catalytic activity of membrane-bound human VAP-1 in static conditions, suggesting that glycosylation regulates the functional properties of VAP-1.	Nitrogen	29-30	amine oxidase copper containing 3	Homo sapiens	218-223
16082728-7	2005	Furthermore, mutation of the N-linked attachment sites strategically located on the top of the molecule reduces lymphocyte adhesion in non-static conditions, and enhances the catalytic activity of membrane-bound human VAP-1 in static conditions, suggesting that glycosylation regulates the functional properties of VAP-1.	Nitrogen	29-30	amine oxidase copper containing 3	Homo sapiens	315-320
3316986-1	1987	Mutations in the ARD1 gene prevent yeast cells from displaying G1-specific growth arrest in response to nitrogen deprivation and cause MATa haploids (but not MAT alpha haploids) to be mating defective.	Nitrogen	104-112	peptide alpha-N-acetyltransferase complex A subunit ARD1	Saccharomyces cerevisiae S288C	17-21
2820395-1	1987	We prepared unlabeled and 3H-labeled analogs of platelet-activating factor (PAF) containing a N-methylcarbamyl residue at the sn-2 position.	Nitrogen	94-95	PCNA clamp associated factor	Homo sapiens	48-74
2820395-1	1987	We prepared unlabeled and 3H-labeled analogs of platelet-activating factor (PAF) containing a N-methylcarbamyl residue at the sn-2 position.	Nitrogen	94-95	PCNA clamp associated factor	Homo sapiens	76-79
15992386-2	2005	Formation of a complex of soluble N-ethylmaleimide-sensitive fusion protein receptor (SNARE) proteins, including vesicle-associated membrane protein-2 (VAMP-2) in the synaptic vesicle membrane, and syntaxin 1 and synaptosomal-associated protein of 25 kDa (SNAP-25) in the plasma membrane, is essential for exocytosis.	Nitrogen	34-35	vesicle-associated membrane protein 2	Rattus norvegicus	113-150
3497124-5	1987	Under nitrogen, the degradation of BSA was not altered by the addition of DNA, but in the presence of oxygen less BSA was lost for a given dose when DNA was present.	Nitrogen	6-14	albumin	Bos taurus	35-38
3626536-5	1987	TTR, TF, and RBP correlated significantly with TB and NTB VIS nitrogen and TB CAR nitrogen.	Nitrogen	62-70	retinol binding protein 4	Rattus norvegicus	13-16
3626536-6	1987	The correlation of NTB VIS nitrogen with TTR, TF, and RBP (r range = 0.70-0.85, P less than 0.001) was higher than for TB rats (r range = 0.53-0.57, P less than 0.005).	Nitrogen	27-35	retinol binding protein 4	Rattus norvegicus	54-57
15992386-2	2005	Formation of a complex of soluble N-ethylmaleimide-sensitive fusion protein receptor (SNARE) proteins, including vesicle-associated membrane protein-2 (VAMP-2) in the synaptic vesicle membrane, and syntaxin 1 and synaptosomal-associated protein of 25 kDa (SNAP-25) in the plasma membrane, is essential for exocytosis.	Nitrogen	34-35	vesicle-associated membrane protein 2	Rattus norvegicus	152-158
3626536-7	1987	The correlation of TB carcass nitrogen (r range = 0.47-0.51, P less than 0.01) with TTR, TF, and RBP was higher than for NTB carcass nitrogen which was not significant (r range = 0.25-0.37, P less than 0.57).	Nitrogen	30-38	retinol binding protein 4	Rattus norvegicus	97-100
3626536-8	1987	These data indicate that TTR, TF, and RBP do correlate with components of body nitrogen mass, but factors other than nutrition may influence their metabolism in the TB host.	Nitrogen	79-87	retinol binding protein 4	Rattus norvegicus	38-41
15950943-1	2005	The Prnd-encoded prion protein (PrP)-like protein, Doppel (Dpl), is a homologue of Prnp-encoded PrP, and is N-glycosylated protein with glycosylphosphatidylinositol anchor like PrP.	Nitrogen	108-109	prion protein	Mus musculus	32-35
15890371-5	2005	Blood lymphocytes were also found to catalyze the CYP dependent N-demethylation of N-nitrosodimethylamine (NDMA), which like in liver increased 2-3 fold following pretreatment of rats with known CYP2E1 inducers.	Nitrogen	64-65	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	50-53
3613887-3	1987	HBsAg seroconversion to its antibody occurred in 15 (93.8%) of the 16 patients positive for IgM anti-HBc with S/N ratios above 5.0, as did 5 (26.3%) of the 19 with S/N ratios between 2.1 to 5.0, and none (0%) of the 38 negative for IgM anti-HBc (S/N ratios less than 2.1).	Nitrogen	112-113	keratin 88, pseudogene	Homo sapiens	101-104
3613887-5	1987	However, low S/N ratios (2.1-5.0) of IgM anti-HBc were observed in the early stage of some patients with acute type B hepatitis, and would increase to a level greater than 5.0 when assayed again 1-2 weeks later.	Nitrogen	15-16	keratin 88, pseudogene	Homo sapiens	46-49
15998011-0	2005	Weak carbon-hydrogen-nitrogen interactions affect the heterocyclic ligand bonding modes in barium complexes containing eta2-tetrazolato and eta2-pentazolato ligands.	Nitrogen	21-29	DNA polymerase iota	Homo sapiens	119-123
15998011-0	2005	Weak carbon-hydrogen-nitrogen interactions affect the heterocyclic ligand bonding modes in barium complexes containing eta2-tetrazolato and eta2-pentazolato ligands.	Nitrogen	21-29	DNA polymerase iota	Homo sapiens	140-144
3470522-5	1987	Comparison of the data for various folate analogues reveals a striking dependence of TS inhibitory potency upon the number of nitrogens in the folate pyrazine ring.	Nitrogen	126-135	thymidylate synthetase	Homo sapiens	85-87
16050741-1	2005	Quenching mechanisms of the Li3p and Li4p states in collision with the nitrogen molecule are studied by laser-induced fluorescence spectroscopy and by a quantum chemical calculation.	Nitrogen	71-79	lipase family member N	Homo sapiens	37-41
16039527-6	2005	These results support the concept that rational N-methylation of hIAPP amyloid-core sequences may be a valuable strategy to design pancreatic-amyloid diagnostics and therapeutics for type II diabetes.	Nitrogen	48-49	islet amyloid polypeptide	Homo sapiens	65-70
3816803-4	1987	The results show that the N-linked carbohydrate chains of colligin are exclusively the high-mannose type, of which (Man)8(GlcNAc)2 and (Man)9(GlcNAc)2 make up 77%.	Nitrogen	26-27	serine (or cysteine) peptidase inhibitor, clade H, member 1	Mus musculus	58-66
15821045-1	2005	Ifosfamide nephrotoxicity is attributed to the formation of a toxic metabolite, chloroacetaldehyde, via N-dechloroethylation, a reaction that is purportedly catalyzed by CYP3A and CYP2B6.	Nitrogen	104-105	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	180-186
16154903-1	2005	Syntaxin 10 is a soluble N-ethylmaleimide sensitive factor attachment protein receptor (SNARE) protein localized to the trans-Golgi network (TGN), where two other members of the syntaxin family, syntaxins 6 and 16, also reside.	Nitrogen	25-26	syntaxin 10	Homo sapiens	0-11
3025596-9	1986	The expression of the longer hybrids had deleterious effects on cell growth; PUT2-lacZ366-containing strains failed to grow on proline as the sole source of nitrogen.	Nitrogen	157-165	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	77-81
2679559-1	1989	Proton and nitrogen signals of the guanidinium amines in [N eta 1, N eta 2 15N Arg]Taq I endonuclease were observed using isotope filtered experiments and proton detected 1H[15N] heterocorrelated two dimensional NMR spectroscopy.	Nitrogen	11-19	secreted phosphoprotein 1	Homo sapiens	60-65
15925307-3	2005	In this way we have identified two genes, NGR1 and GID7, whose disruption leads to an enhanced catabolism of sugar in an industrial strain and/or a laboratory strain, during growth in a chemically defined grape juice medium with limiting nitrogen.	Nitrogen	238-246	Ngr1p	Saccharomyces cerevisiae S288C	42-46
2549247-4	1989	In addition, the SAR for nitrogen substitution in the above series is explored with respect to the overall opioid receptor subtype binding profile.	Nitrogen	25-33	sarcosinemia autosomal recessive	Mus musculus	17-20
3095957-2	1986	After treatment of mice with 4-MeSO2-TCB (100 mg/kg), the pulmonary N-demethylation of aminopyrine in vitro was significantly decreased, while hepatic N-demethylation was concomitantly increased, as compared to tissue from control mice.	Nitrogen	68-69	pyruvate kinase M1/2	Homo sapiens	37-40
16110782-5	2005	We have shown that C. glabrata STE11 can complement the mating defect and partially rescue the reduced nitrogen starvation induced filamentation of S. cerevisiae ste11 mutants.	Nitrogen	103-111	mitogen-activated protein kinase kinase kinase STE11	Saccharomyces cerevisiae S288C	31-36
2944558-3	1986	The measurement of m/z 64 for SO2 in a CO2-scavenged discharge can be used to determine the amount of sulfur originally introduced into the interface; carbon is quantified as HCN (m/z 27) in a nitrogen-scavenged discharge.	Nitrogen	193-201	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	175-178
3709076-3	1986	Absorption of total nitrogen and of 14 amino acid residues occurred to a significantly greater extent from the low molecular weight LH1 than from the higher molecular weight LH2.	Nitrogen	20-28	procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	Homo sapiens	132-135
2941452-13	1986	Further evidence for an alpha granule localization of PADGEM protein was provided by nitrogen cavitation of resting platelets followed by metrizamide density gradient centrifugation; PADGEM protein codistributed with platelet factor 4.	Nitrogen	85-93	selectin P	Homo sapiens	54-60
2554755-8	1989	Moreover, because this technique was used successfully in the immobilization of periodic acid--Schiff positive staining glycoprotein 1 prepared from human erythrocytes and human alpha 2-macroglobulin, the technique should also be useful for other membrane or secreted proteins that possess N-linked sugar chains containing bisecting N-acetylglucosamine or a high amount of sialic acid.	Nitrogen	290-291	alpha-2-macroglobulin	Homo sapiens	178-199
2570348-3	1989	beta-Galactosidase and glutamine synthetase expression in chromosomally integrated GLN1-lacZ fusion strains were co-regulated in response to a shift from glutamine to glutamate as the nitrogen source, purine limitation, and 3-aminotriazole-induced histidine starvation.	Nitrogen	184-192	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	83-87
16110782-5	2005	We have shown that C. glabrata STE11 can complement the mating defect and partially rescue the reduced nitrogen starvation induced filamentation of S. cerevisiae ste11 mutants.	Nitrogen	103-111	mitogen-activated protein kinase kinase kinase STE11	Saccharomyces cerevisiae S288C	162-167
2525050-6	1989	The absorption maxima of bovine artificial pigments formed by regenerating opsin with the 11-cis dihydro series of chromophores support a color regulation model for bovine rhodopsin in which the chromophore-binding site of the protein has two negative charges: one directly hydrogen bonded to the Schiff base nitrogen and another near carbon-13.	Nitrogen	309-317	rhodopsin	Bos taurus	172-181
15794922-8	2005	Moreover, another N-glycosylation mutant with a LLO defect, alg6, was respiratory deficient.	Nitrogen	18-19	dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase	Saccharomyces cerevisiae S288C	60-64
18588011-3	1989	Also cells grown on yeast nitrogen base without amino acids with casamino acids degraded the hEGF after cell growth as opposed to a yeast extract, peptone, and dextrose (YEPD) medium, which elicited no measurable extracellular proteolysis of the hEGF.	Nitrogen	26-34	epidermal growth factor	Homo sapiens	93-97
18588011-3	1989	Also cells grown on yeast nitrogen base without amino acids with casamino acids degraded the hEGF after cell growth as opposed to a yeast extract, peptone, and dextrose (YEPD) medium, which elicited no measurable extracellular proteolysis of the hEGF.	Nitrogen	26-34	epidermal growth factor	Homo sapiens	246-250
3011986-7	1986	The Cu(II)-alpha-lactalbumin complex gave a typical axially symmetric spectrum (g parallel = 2.260, g perpendicular = 2.056, A parallel = 171 G) with a partially resolved superhyperfine interaction attributable to at least one directly coordinated nitrogen ligand.	Nitrogen	248-256	lactalbumin alpha	Bos taurus	11-28
16096263-6	2005	Scanning N-glycosylation mapping of EC1 in the cell-free system and in transfected cells showed that the C-terminus of both AE1 and SAO TM1 were at the same position relative to the membrane.	Nitrogen	9-10	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	124-127
3023826-5	1986	P70 appears to be the aglycosylated form of gp95, the presumptive intracellular precursor of the receptor-related species gp120 that is secreted by A431 but not Hep 3B cells; gp120 has a complex pattern of N-linked glycosylation, with consequent molecular weight and charge heterogeneity.	Nitrogen	206-207	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	122-127
3023826-5	1986	P70 appears to be the aglycosylated form of gp95, the presumptive intracellular precursor of the receptor-related species gp120 that is secreted by A431 but not Hep 3B cells; gp120 has a complex pattern of N-linked glycosylation, with consequent molecular weight and charge heterogeneity.	Nitrogen	206-207	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	175-180
2715460-0	1989	Long-term evaluation of a prolonged-release formulation of N-methionyl bovine somatotropin in lactating dairy cows.	Nitrogen	59-60	somatotropin	Bos taurus	78-90
15805486-0	2005	The sulfate transporter SST1 is crucial for symbiotic nitrogen fixation in Lotus japonicus root nodules.	Nitrogen	54-62	Sst1	Lotus japonicus	24-28
2540426-5	1989	Disruption of the IRA1 gene resulted in sensitivity to nitrogen starvation and heat shock.	Nitrogen	55-63	GTPase-activating protein IRA1	Saccharomyces cerevisiae S288C	18-22
4054123-5	1985	In addition, hydrogen bonds exist between the N(1) and N(3) atoms of FMN and the apoprotein.	Nitrogen	46-47	formin 1	Homo sapiens	69-72
15780659-2	2005	One such system, the target of rapamycin (Tor) proteins, senses nutrients and uses the GATA activators Gln3p and Nil1p to regulate translation in response to low-quality carbon and nitrogen.	Nitrogen	181-189	Gat1p	Saccharomyces cerevisiae S288C	113-118
4016771-0	1985	Increased glutathione-S-transferase activity in a cell line with acquired resistance to nitrogen mustards.	Nitrogen	88-96	hematopoietic prostaglandin D synthase	Rattus norvegicus	10-35
2911462-4	1989	Xint-1 shares several characteristics of secreted proteins with the other int-1 homologs: it has a hydrophobic leader, multiple conserved potential N-linked glycosylation sites and is rich in cysteine residues.	Nitrogen	148-149	Wnt family member 1 S homeolog	Xenopus laevis	0-6
2911462-4	1989	Xint-1 shares several characteristics of secreted proteins with the other int-1 homologs: it has a hydrophobic leader, multiple conserved potential N-linked glycosylation sites and is rich in cysteine residues.	Nitrogen	148-149	Wnt family member 1 S homeolog	Xenopus laevis	1-6
15780659-4	2005	When carbon and nitrogen are abundant, the phosphorylated Ure2p anchors the also phosphorylated Gln3p and Nil1p in the cytoplasm.	Nitrogen	16-24	Gat1p	Saccharomyces cerevisiae S288C	106-111
2647705-0	1989	Nitrogen and protein metabolism and metabolites in plasma and urine of beef steers treated with somatotropin.	Nitrogen	0-8	somatotropin	Bos taurus	96-108
2647705-1	1989	The objectives of this study were to determine the effects of daily injection of bovine somatotropin (bST) on the metabolism of N and 1-[14C]leucine and on hormone and metabolite concentrations in growing beef steers.	Nitrogen	128-129	somatotropin	Bos taurus	88-100
15780659-5	2005	Upon a shift from high- to low-quality nitrogen or treatment with rapamycin all three proteins are dephosphorylated, causing Gln3p and Nil1p to enter the nucleus and promote transcription.	Nitrogen	39-47	Gat1p	Saccharomyces cerevisiae S288C	135-140
3872909-9	1985	It was also found that 12-O-tetradecanoyl-phorbol 13-acetate (TPA) switched 23A4 cells and normal lymphocytes to the selective formation of N-glycosylated IgE-binding factor, and induced the release of GIF from the cells.	Nitrogen	140-141	cobalamin binding intrinsic factor	Homo sapiens	202-205
15723386-0	2005	Changes in N-linked sugar chain patterns induced by moderate-to-high expression of the galactosyltransferase I gene in a brain-derived cell line, CG4.	Nitrogen	11-12	beta-1,4-galactosyltransferase 7	Homo sapiens	87-110
3986776-0	1985	Carbamoylation of glutathione reductase and changes in cellular and chromosome morphology in a rat cell line resistant to nitrogen mustards but collaterally sensitive to nitrosoureas.	Nitrogen	122-130	glutathione-disulfide reductase	Rattus norvegicus	18-39
6470005-3	1984	The results are consistent with the proposal of nitrogen and oxygen atoms as ligands to the metal in the active site of glyoxalase I.	Nitrogen	48-56	glyoxalase I	Homo sapiens	120-132
2925957-6	1989	Postabsorptive use of nitrogen and carbon was altered by somatotropin as reflected by greater secretion in milk.	Nitrogen	22-30	somatotropin	Bos taurus	57-69
3148445-5	1988	The rat t-PA sequence contains two putative N-glycosylation sites at Asn-120 and Asn-452, while human t-PA has an additional glycosylation site at Asn-187.	Nitrogen	44-45	plasminogen activator, tissue type	Rattus norvegicus	8-12
16666423-7	1988	The NR antibody cross-reacting protein was also seen in hydroponically grown plants when NH(4)Cl(-) was the only added form of nitrogen.	Nitrogen	127-135	nitrate reductase [NADH] 1	Zea mays	4-6
2463161-4	1988	The nucleotide sequence of the m-mb-1 gene encodes a putative membrane glycoprotein with 220 amino acids, which includes a leader sequence, a putative extracellular domain with two potential N-glycosylation sites, a transmembrane portion and a putative intracellular domain.	Nitrogen	191-192	histocompatibility 2, M region locus 1	Mus musculus	33-37
3413294-4	1988	Significant correlations between plasma levels of IR-7B2 and those of blood urea nitrogen, creatinine and beta 2-microglobulin were evident in non-dialyzed CRF patients.	Nitrogen	81-89	secretogranin V	Homo sapiens	53-56
2452086-12	1988	The inhibition of N-glycosylation by tunicamycin abolished the effect of interleukin-6 on the secretion of alpha 2-macroglobulin, indicating a possible role of interleukin-6 on N-glycosylation.	Nitrogen	18-19	alpha-2-macroglobulin	Homo sapiens	107-128
2452086-12	1988	The inhibition of N-glycosylation by tunicamycin abolished the effect of interleukin-6 on the secretion of alpha 2-macroglobulin, indicating a possible role of interleukin-6 on N-glycosylation.	Nitrogen	177-178	alpha-2-macroglobulin	Homo sapiens	107-128
3280136-7	1988	Starvation for nitrogen further induced (6- to 8-fold) transcription of IME1, but, as expected, the induction was found only in MATa/MAT alpha or rme1-1/rme1-1 diploids.	Nitrogen	15-23	Rme1p	Saccharomyces cerevisiae S288C	146-152
3280136-7	1988	Starvation for nitrogen further induced (6- to 8-fold) transcription of IME1, but, as expected, the induction was found only in MATa/MAT alpha or rme1-1/rme1-1 diploids.	Nitrogen	15-23	Rme1p	Saccharomyces cerevisiae S288C	146-150
3178492-2	1988	Human and animal erythrocytes were agglutinated by lectins SBA, DBA, WFA, VAA II, RCA II, and WGA which have a specificity for the N-acetyl group of galactosamine (NAc-D-Gal) or glucosamine (NAc-D-Gal); this effect was abolished after treatment of erythrocytes with influenza C virus.	Nitrogen	131-132	synuclein alpha	Homo sapiens	164-167
3178492-2	1988	Human and animal erythrocytes were agglutinated by lectins SBA, DBA, WFA, VAA II, RCA II, and WGA which have a specificity for the N-acetyl group of galactosamine (NAc-D-Gal) or glucosamine (NAc-D-Gal); this effect was abolished after treatment of erythrocytes with influenza C virus.	Nitrogen	131-132	synuclein alpha	Homo sapiens	191-194
3146461-3	1988	The C4A and C4B gene products differ in reactivity with C4A being more reactive with nitrogen nucleophiles, including hydralazine and isoniazid (drugs which induce SLE), than with oxygen nucleophiles.	Nitrogen	85-93	complement C4A (Rodgers blood group)	Homo sapiens	4-7
3146461-3	1988	The C4A and C4B gene products differ in reactivity with C4A being more reactive with nitrogen nucleophiles, including hydralazine and isoniazid (drugs which induce SLE), than with oxygen nucleophiles.	Nitrogen	85-93	complement C4A (Rodgers blood group)	Homo sapiens	56-59
3121434-1	1987	A mutation has been identified that prevents Saccharomyces cerevisiae cells from growing on proline as the sole source of nitrogen, causes noninducible expression of the PUT1 and PUT2 genes, and is completely recessive.	Nitrogen	122-130	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	179-183
2827734-6	1987	The copper hyperfine line at low field in the EPR spectrum of the S-(p-bromobenzyl)glutathione complex of 63Cu(II) glyoxalase I shows a triplet structure, indicative of coupling to one nitrogen ligand in the equatorial plane.	Nitrogen	185-193	glyoxalase I	Homo sapiens	115-127
2827734-8	1987	By addition of the spectrum of the S-(p-bromobenzyl)glutathione complex and a spectrum corresponding to two nitrogen ligands with two different coupling constants, a good fit was obtained for the low-field region of the asymmetric spectrum of free 63Cu(II) glyoxalase I.	Nitrogen	108-116	glyoxalase I	Homo sapiens	257-269
2826321-7	1987	In order to elucidate the biochemical function of myocardial PI-PLC in hypoxia, PI-PLC along with phospholipase A2 (PLA2) was investigated in N2 gas-saturated buffer up to for 24 hours.	Nitrogen	142-144	phospholipase A2 group IB	Rattus norvegicus	116-120
2960320-5	1987	This transition is identified as a time-dependent change in conformation of the column-purified myosin from a 10 S to 6 S form and is caused by slow oxidation of the column-purified myosin, since it could be prevented by storage under N2 and reversed by 5 mM-dithiothreitol.	Nitrogen	235-237	myosin heavy chain 14	Homo sapiens	96-102
2960320-5	1987	This transition is identified as a time-dependent change in conformation of the column-purified myosin from a 10 S to 6 S form and is caused by slow oxidation of the column-purified myosin, since it could be prevented by storage under N2 and reversed by 5 mM-dithiothreitol.	Nitrogen	235-237	myosin heavy chain 14	Homo sapiens	182-188
3115177-1	1987	Estramustine phosphate, an estradiol nitrogen-mustard derivative is a microtubule-associated protein (MAP)-binding microtubule inhibitor, used in the therapy of prostatic carcinoma.	Nitrogen	37-45	regulator of microtubule dynamics 1	Homo sapiens	70-100
3115177-1	1987	Estramustine phosphate, an estradiol nitrogen-mustard derivative is a microtubule-associated protein (MAP)-binding microtubule inhibitor, used in the therapy of prostatic carcinoma.	Nitrogen	37-45	regulator of microtubule dynamics 1	Homo sapiens	102-105
3301804-3	1987	However, steady-state DAL5 mRNA levels dropped precipitously when a repressive nitrogen source was provided.	Nitrogen	79-87	allantoate permease	Saccharomyces cerevisiae S288C	22-26
3301804-4	1987	These control characteristics of DAL5 expression make this gene a good model with which to unravel the mechanism of nitrogen catabolite repression.	Nitrogen	116-124	allantoate permease	Saccharomyces cerevisiae S288C	33-37
3036815-10	1987	A comparison of the kinetic properties of native and N-ethylmaleimide-modified fructose-1,6-bisphosphatase reveals differences in some properties but none is so striking as the complete loss of fructose 2,6-bisphosphate sensitivity.	Nitrogen	53-54	fructose-bisphosphatase 1	Sus scrofa	79-106
3295041-1	1987	The subcellular localization of beta2-microglobulin (beta 2m) in human neutrophils was determined by an enzyme-linked immunosorbent assay on subcellular fractions obtained by Percoll density gradient centrifugation of neutrophils disrupted by nitrogen cavitation.	Nitrogen	243-251	beta-2-microglobulin	Homo sapiens	32-51
3295041-1	1987	The subcellular localization of beta2-microglobulin (beta 2m) in human neutrophils was determined by an enzyme-linked immunosorbent assay on subcellular fractions obtained by Percoll density gradient centrifugation of neutrophils disrupted by nitrogen cavitation.	Nitrogen	243-251	beta-2-microglobulin	Homo sapiens	53-60
3600602-10	1987	These data suggest that differential expression of GST subunits may contribute to the nitrogen mustard-resistant phenotype.	Nitrogen	86-94	hematopoietic prostaglandin D synthase	Rattus norvegicus	51-54
3552673-8	1987	The adverse effect of the NPI1 gene product on general amino-acid permease activity is reduced when NPI1 gene dose is decreased to 1 gene copy in a diploid strain, regardless of the nitrogen source.	Nitrogen	182-190	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	26-30
3025246-7	1987	When an iv dose of 1 microgram/kg CRH was administered during the saline infusions, peak plasma ACTH and cortisol levels were 27.7 +/- 6.3 pg/ml and 17.5 +/- 1.0 micrograms/dl, respectively, during the HS infusion and 15.6 +/- 1.7 pg/ml and 13.4 +/- 1.2 micrograms/dl during the NS infusion.	Nitrogen	279-281	corticotropin releasing hormone	Homo sapiens	34-37
3558202-1	1987	Exposure of CD-1 mice to subanesthetic partial pressures of N2O (0.5 atm) or N2 (10-20 atm) for periods up to 14 days results in up to 40% decreases in the mean threshold pressure eliciting type I high-pressure neurological syndrome (HPNS) seizures, and in increases up to 38% in the N2 partial pressure producing anesthesia.	Nitrogen	60-62	CD1 antigen complex	Mus musculus	12-16
3098726-16	1986	When blood was taken 3 h post-injection, both GRF- and pGH-treated pigs had lower blood-urea nitrogen concentrations.	Nitrogen	93-101	growth hormone releasing hormone	Sus scrofa	46-49
3815621-5	1986	Thus, both types of N-acylated phospholipids can be analyzed by consecutive phospholipase A2 and phospholipase D treatment.	Nitrogen	20-21	LOC104974671	Bos taurus	76-92
18964168-2	1986	In a solution of 0.1M potassium thiocyanate and 0.01M potassium sulphate at a nitrogen flow-rate of 3.5-5.0 ml sec , the rate of production of HCN was a linear function of the generation current I from 10 to 200 microA.	Nitrogen	78-86	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	143-146
3727179-1	1986	The volume of nitrogen eliminated (VN2) and washout rate constant (k) during a 2-h period of O2 breathing in the rat was altered in response to changes in body temperature.	Nitrogen	14-22	vomeronasal 1 receptor 102	Rattus norvegicus	35-38
3713815-4	1986	However, nitro-PAH may also be formed during source-receptor transport by atmospheric reactions of adsorbed or gas-phase PAH with oxides of nitrogen, nitric acid and other atmospherically important species such as the OH radical.	Nitrogen	140-148	Henna	Drosophila melanogaster	15-18
3954746-5	1986	The simulation of the diferric ovotransferrin spectrum suggests a first co-ordination shell consisting of six low-Z ligands (nitrogen/oxygen), two ligands at a distance of approx.	Nitrogen	125-133	transferrin (ovotransferrin)	Gallus gallus	31-45
6327700-5	1984	Acidification of solutions of either native or denatured porphyrin cytochrome c markedly alters both the visible absorbance and fluorescence of the protein consistent with protonation of two pyrrole nitrogens on the porphyrin.	Nitrogen	199-208	cytochrome c, somatic	Equus caballus	67-79
15780085-7	2005	Consequently, the midkine antisense ODN-treated animals exhibited less severe renal damage than untreated or midkine sense ODN-treated animals 2 days after I/R as assessed by morphologic criteria and blood urea nitrogen (BUN) and serum creatinine levels.	Nitrogen	211-219	midkine	Mus musculus	18-25
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	139-140	complement C4A (Rodgers blood group)	Homo sapiens	70-73
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	145-146	complement C4A (Rodgers blood group)	Homo sapiens	70-73
15686893-7	2005	From the analysis it appears that the nitrogen atom of the aminoethoxyphenyl substituent and 6-hydroxy substituent of the tetrahydroisoquinoline nucleus play important roles for ER(alpha)/ER(beta) selectivity in addition to R(1) and R(2) substituents.	Nitrogen	38-46	estrogen receptor 2	Homo sapiens	188-196
3931273-7	1985	The patients receiving MAA had enhanced nitrogen retention, visceral protein mass, and indices of survival.	Nitrogen	40-48	MAA	Homo sapiens	23-26
15629807-3	2005	In this Caprogen) diluent spermatozoa are stored under N2 gas in the presence of catalase.	Nitrogen	55-57	catalase	Bos taurus	81-89
24249451-10	1985	Glutamine synthetase, on the other hand was involved in the assimilation of physiological amounts of nitrogen.	Nitrogen	101-109	hypothetical protein	Arabidopsis thaliana	0-20
15489236-6	2005	Computer-graphic modeling of N-62 StAR indicated these peptides correspond to the C-terminal alpha4 helix and that residues Leu(275), Thr(263), and Arg(272) in alpha4 form stabilizing interactions with Gln(128), Asp(150), and Asp(106) in adjacent loops.	Nitrogen	29-30	steroidogenic acute regulatory protein	Homo sapiens	34-38
3986844-1	1985	Reaction of 1,5-anhydro-4-O-benzoyl-2,3,6-trideoxy-3-C-methyl-3-trifluoro-acetami no-L-lyxo-hex-1-enitol with daunomycinone in the presence of anhydrous toluene-p-sulfonic acid in benzene, followed by removal of the N- and O-protecting groups under mild conditions, gave 3"-C-methyldaunorubicin.	Nitrogen	216-217	exonuclease 1	Homo sapiens	92-97
2987163-0	1985	Prevention of penetration hindrance in cerium-based glucose-6-phosphatase cytochemistry by freezing tissue in melting nitrogen.	Nitrogen	118-126	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	52-73
15665496-0	2005	Pradimicin resistance of yeast is caused by a mutation of the putative N-glycosylation sites of osmosensor protein Sln1.	Nitrogen	71-72	histidine kinase	Saccharomyces cerevisiae S288C	115-119
15665496-4	2005	A mutant, sln1 DeltaNG, that lacks the putative N-glycosylation sites in the extracellular domain became resistant to pradimicin.	Nitrogen	20-21	histidine kinase	Saccharomyces cerevisiae S288C	10-14
6334140-4	1984	In cocultures consisting of NS and TBS (1:1), TCGF production by NS was markedly suppressed.	Nitrogen	28-30	interleukin 2	Mus musculus	46-50
15632429-0	2005	Disruption of MRG19 results in altered nitrogen metabolic status and defective pseudohyphal development in Saccharomyces cerevisiae.	Nitrogen	39-47	Csr2p	Saccharomyces cerevisiae S288C	14-19
6477897-5	1984	Thus, the mechanism of formation of bathorhodopsin (in bovine rhodopsin system) may be considered as some change of the interaction between the conjugated double-bond system from C-9 to the Schiff base nitrogen and its surrounding charges in opsin, caused by rotation of 11-12 double-bond.	Nitrogen	202-210	rhodopsin	Bos taurus	41-50
15632429-2	2005	Here, it is shown that glucose repression of MRG19 is overcome upon nitrogen withdrawal, suggesting that MRG19 is a regulator of carbon and nitrogen metabolism.	Nitrogen	68-76	Csr2p	Saccharomyces cerevisiae S288C	45-50
15632429-2	2005	Here, it is shown that glucose repression of MRG19 is overcome upon nitrogen withdrawal, suggesting that MRG19 is a regulator of carbon and nitrogen metabolism.	Nitrogen	68-76	Csr2p	Saccharomyces cerevisiae S288C	105-110
15632429-2	2005	Here, it is shown that glucose repression of MRG19 is overcome upon nitrogen withdrawal, suggesting that MRG19 is a regulator of carbon and nitrogen metabolism.	Nitrogen	140-148	Csr2p	Saccharomyces cerevisiae S288C	45-50
6332620-10	1984	In the presence of glucose, almost all nitrogen of the metabolized glutamine was accounted for as NH3 released via the glutaminase and/or glutamate dehydrogenase reactions.	Nitrogen	39-47	glutaminase	Rattus norvegicus	119-161
15632429-2	2005	Here, it is shown that glucose repression of MRG19 is overcome upon nitrogen withdrawal, suggesting that MRG19 is a regulator of carbon and nitrogen metabolism.	Nitrogen	140-148	Csr2p	Saccharomyces cerevisiae S288C	105-110
15632429-3	2005	beta-Galactosidase activity fostered by the promoter of GDH1/3, which encode anabolic enzymes of nitrogen metabolism, was altered in an MRG19 disruptant.	Nitrogen	97-105	Csr2p	Saccharomyces cerevisiae S288C	136-141
6420398-5	1984	This analysis indicated that a D-glucuronosyl residue is recognized as a substrate if it is linked at C-1 to an N-acetylated glucosamine residue and at C-4 to an N-sulfated unit.	Nitrogen	112-113	Rho GTPase activating protein 4	Mus musculus	102-105
15632429-4	2005	As compared to the wild-type strain, the MRG19 disruptant showed a decrease in the ratio of 2-oxoglutarate to glutamate under nitrogen-limited conditions.	Nitrogen	126-134	Csr2p	Saccharomyces cerevisiae S288C	41-46
6242325-10	1984	Irradiation of 7-cis- and 9-cis-rhodopsins at liquid nitrogen temperature produced the same bathorhodopsin as that from 11-cis-rhodopsin, indicating that the chromophore of bathorhodopsin should be in all-trans or transoid form.	Nitrogen	53-61	rhodopsin	Bos taurus	32-41
15632429-5	2005	MRG19 disruptants showed reduced pseudohyphal formation and enhanced sporulation, a phenomenon that occurs under conditions of both nitrogen and carbon withdrawal.	Nitrogen	132-140	Csr2p	Saccharomyces cerevisiae S288C	0-5
15632429-6	2005	These studies revealed that MRG19 regulates carbon and nitrogen metabolism, as well as morphogenetic changes, suggesting that MRG19 is a component of the link between the metabolic status of the cell and the corresponding developmental pathway.	Nitrogen	55-63	Csr2p	Saccharomyces cerevisiae S288C	28-33
15632429-6	2005	These studies revealed that MRG19 regulates carbon and nitrogen metabolism, as well as morphogenetic changes, suggesting that MRG19 is a component of the link between the metabolic status of the cell and the corresponding developmental pathway.	Nitrogen	55-63	Csr2p	Saccharomyces cerevisiae S288C	126-131
6373801-9	1984	Inhibition of N-linked glycosylation of apolipoprotein B with tunicamycin affects neither the assembly of glycerolipids into VLDL nor the secretion of the VLDL particle, indicating that aglyco -apolipoprotein B can serve as a functional component for VLDL assembly and secretion.	Nitrogen	14-15	apolipoprotein B	Gallus gallus	40-56
15869978-0	2005	Modelling of nitrogen release from MBT waste.	Nitrogen	13-21	proteinase 3	Homo sapiens	35-38
6325453-21	1984	Further, the overall kinetics with which Ns activity in cholate extracts and Ns activity in the purified protein reconstituted the Ns-deficient adenylyl cyclase system of cyc- S49 cells was also indistinguishable.	Nitrogen	41-43	peptidylprolyl isomerase A, pseudogene 1	Mus musculus	153-156
6358411-7	1983	CuATP-stimulated LHRH release from granules incubated under N2 was 50% of that incubated under air.	Nitrogen	60-62	gonadotropin releasing hormone 1	Rattus norvegicus	17-21
15519172-6	2004	Further structural exploration of the exocyclic N-atom in 3,6-disubstituted derivatives produced compounds potent at both DAT and NET.	Nitrogen	48-49	solute carrier family 6 member 3	Rattus norvegicus	122-125
6652560-2	1983	Model reactions of glycine ethyl ester and piperidine with formaldehyde and melatonin suggested that coupling first occurred through the indole nitrogen and then a stable bond was formed at C-2.	Nitrogen	144-152	complement C2	Homo sapiens	190-193
6854316-4	1983	Reaction with the form HL-2 (only the amino nitrogen protonated), the dominant form of this species, proceeds by the expected rat limiting water loss (dissociative or Eigen) mechanism with rate constants of 9.3 X 10(7) M-1 sec-1 (+/- 24%) for mono and 5.1 X 10(7) M-1 sec-1 (+/- 25%) for bis complex formation.	Nitrogen	44-52	secretory blood group 1	Rattus norvegicus	223-228
6854316-4	1983	Reaction with the form HL-2 (only the amino nitrogen protonated), the dominant form of this species, proceeds by the expected rat limiting water loss (dissociative or Eigen) mechanism with rate constants of 9.3 X 10(7) M-1 sec-1 (+/- 24%) for mono and 5.1 X 10(7) M-1 sec-1 (+/- 25%) for bis complex formation.	Nitrogen	44-52	secretory blood group 1	Rattus norvegicus	268-273
16662876-0	1983	Nitrate Reductase Activity in Shoots and Roots of Maize Seedlings as Affected by the Form of Nitrogen Nutrition and the pH of the Nutrient Solution.	Nitrogen	93-101	nitrate reductase [NADH] 1	Zea mays	0-17
6296107-6	1983	Studies presented here show that the ESR spectra of nitrosyl elephant myoglobin exhibit 9-line superhyperfine splitting well above liquid nitrogen temperatures, similar to the temperature profiles of isolated heme complexes (Morse, R.H. (1980) Fed.	Nitrogen	138-146	myoglobin	Homo sapiens	70-79
15578946-1	2004	A family of three nitric oxide synthase 1(NOS) isoforms produces nitric oxide (NO*) and L-citrulline via a stepwise oxidation of the guanidinium nitrogen of L-arginine.	Nitrogen	145-153	nitric oxide synthase 1	Homo sapiens	18-41
7097715-9	1982	These results suggest that for nitrogen heterocycles there may be a relationship of increasing polycyclic size and increasing inhibitory activity toward AHH activity in 3-MC induced rat liver microsomes.	Nitrogen	31-39	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	153-156
15448114-11	2004	These results demonstrate that UGT1A7 is the major isoform catalyzing the N-glucuronidation of DL in RabLM.	Nitrogen	74-75	UDP glucuronosyltransferase 1 family, polypeptide A7	Oryctolagus cuniculus	31-37
6802829-3	1982	A 200% stimulation of N-demethylation by cytochrome b5 was obtained at cytochrome P-450 reductase:cytochrome P-450 ratios similar to those in microsomes, compared to only a 20% stimulation at a ratio of 1:1.	Nitrogen	22-23	cytochrome b5 type A	Homo sapiens	41-54
15556634-4	2004	We demonstrate that Hp-Atg21p is essential for two separate modes of peroxisome degradation, namely glucose-induced macropexophagy and nitrogen limitation-induced microautophagy.	Nitrogen	135-143	Atg21p	Saccharomyces cerevisiae S288C	23-29
15736416-6	2004	Curiously, EGFP-dS3 expression was slightly increased after recovering cells from liquid nitrogen, but it was not possible under those conditions to achieve a significant acceleration of 8-oxoG repair.	Nitrogen	89-97	Ribosomal protein S3	Drosophila melanogaster	16-19
7037618-3	1982	Splenic B cells derived from FTS-treated mice with the CBA/N defect were receptive to T-cell help from normal or immunodeficient mouse T cells.	Nitrogen	59-60	AKT interacting protein	Mus musculus	29-32
7037618-4	1982	Thus, the inability of B cells from mice with the CBA/N defect to accept T -cell help may not be caused by an intrinsic T-cell defect, but by a functional B-cell defect that can be corrected by treatment with FTS in vivo.	Nitrogen	54-55	AKT interacting protein	Mus musculus	209-212
30866189-0	1982	Staphylococcus aureus Growth and Toxin Production in Nitrogen-Packed Sandwiches 1.	Nitrogen	53-61	AT695_RS01930	Staphylococcus aureus	33-38
15546195-1	2004	The cDNA encoding human cystatin C (HCC) was subjected to site-specific substitution of alanine for serine at the position 37, to obtain the Asn(35)-Lys(36)-Ser(37) sequence that is a signal for asparagine-linked (N-linked) glycosylation of protein in eukaryotes, and was transformed into Pichia pastoris X33.	Nitrogen	6-7	cystatin C	Homo sapiens	24-34
7185867-4	1982	The subjects who consumed both the TAD and PEP diets achieved nitrogen balance (2.5 gN +/- 0.7 on the TAD, 2 gN +/- 0 on PEP with the PEP diet resulting in a decrease in plasma cholesterol (32 mg/dl, P less than .005), and a decrease in systolic (5.25 mm/Hg P less than .025) and diastolic blood pressure (5 mm/Hg, P less than .05), which was associated with an increase in urinary sodium excretion (19 +/- 17 mEq/day, P less than .025).	Nitrogen	62-70	progestagen associated endometrial protein	Homo sapiens	43-46
15347604-2	2004	Pro-brain natriuretic peptide (N-BNP) is a newly described cardiac hormone considered to be an effective marker of severity and prognosis of acute coronary syndromes and congestive heart failure.	Nitrogen	31-32	natriuretic peptide B	Homo sapiens	33-36
6801843-4	1982	Net protein utilization (NPU) was determined on the basis of body nitrogen content and protein intake.	Nitrogen	66-74	solute carrier family 6 member 2	Rattus norvegicus	0-3
15504388-0	2004	Chicken growth hormone: further characterization and ontogenic changes of an N-glycosylated isoform in the anterior pituitary gland.	Nitrogen	77-78	growth hormone	Gallus gallus	8-22
6266299-2	1981	In parallel studies, rabbits treated with nitrogen mustard in which granulocytopenia was maintained throughout the 72-h hyperoxic exposure period had less evidence of edematous lung injury and lower concentrations of ACE in their lung lavages than similarly treated rabbits in which granulocytopenia was not maintained.	Nitrogen	42-50	angiotensin-converting enzyme	Oryctolagus cuniculus	217-220
6271833-4	1981	Introduction of a weakly basic nitrogen at C-5 and deletion of the axial methyl group in the B ring, two structural changes forbidden by traditional cannabinoid SAR, resulted in a unique family of benzoquinolines with potent analgetic activity.	Nitrogen	31-39	complement C5	Homo sapiens	43-46
6786888-13	1981	The structure of the N-glycosidically-linked chain was NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 6)[NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 3)]Man(beta 1 leads to 4)GlcNAc(beta 1 leads to 4)[Fuc alpha 1 leads to 6]GlcNAc leads to Asn.	Nitrogen	21-22	adrenoceptor alpha 1D	Homo sapiens	131-138
6786888-13	1981	The structure of the N-glycosidically-linked chain was NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 6)[NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 3)]Man(beta 1 leads to 4)GlcNAc(beta 1 leads to 4)[Fuc alpha 1 leads to 6]GlcNAc leads to Asn.	Nitrogen	21-22	adrenoceptor alpha 1D	Homo sapiens	227-234
6786888-13	1981	The structure of the N-glycosidically-linked chain was NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 6)[NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 3)]Man(beta 1 leads to 4)GlcNAc(beta 1 leads to 4)[Fuc alpha 1 leads to 6]GlcNAc leads to Asn.	Nitrogen	21-22	adrenoceptor alpha 1D	Homo sapiens	227-234
15488990-6	2004	Bovine GLUT8 retains the characteristic structural features of GLUT8 proteins previously identified from other species including membrane spanning helices, glucose transporter motifs, an N-linked glycosylation site on loop 9 and a putative dileucine internalization motif.	Nitrogen	187-188	solute carrier family 2 member 8	Bos taurus	7-12
7452688-2	1980	Only the stereoisomers of the 2,6-dichloro-substituted compounds exhibit for N-CH3 (2e, 3e), N-C2H5 (2f, 3f), and N-C3H7 (2g, 3g) an affinity to the estradiol receptor (Ka values ranging from 9.1 X 10(4) to 9.1 X 10(6)), because the nitrogen atoms are shielded by the ortho-located chlorine atoms; therefore, a binding interaction with hydrophobic receptor areas is possible.	Nitrogen	77-78	estrogen receptor 1	Rattus norvegicus	149-167
7452688-2	1980	Only the stereoisomers of the 2,6-dichloro-substituted compounds exhibit for N-CH3 (2e, 3e), N-C2H5 (2f, 3f), and N-C3H7 (2g, 3g) an affinity to the estradiol receptor (Ka values ranging from 9.1 X 10(4) to 9.1 X 10(6)), because the nitrogen atoms are shielded by the ortho-located chlorine atoms; therefore, a binding interaction with hydrophobic receptor areas is possible.	Nitrogen	233-241	estrogen receptor 1	Rattus norvegicus	149-167
15385504-7	2004	There were increases in total BAL NO levels in both infected groups, but nitrite levels were higher in SP-A(-/-) mice, indicating a reduction in production of higher oxides of nitrogen that was also reflected in lower levels of 3-nitrotyrosine staining in the SP-A(-/-) group.	Nitrogen	176-184	surfactant associated protein A1	Mus musculus	103-107
16661432-6	1980	Increases in N deposition in the normal endosperm induced by N fertilizer are confined primarily to zein.	Nitrogen	13-14	zein	Zea mays	100-104
6769526-1	1980	1 Exposure of guinea-pigs to a CO2-enriched atmosphere (20% CO2, 25% O2, 55% N2) for 1 to 5 h caused a marked, progressive increase of plasma dopamine beta-hydroxylase (DBH) activity which reached its peak after 2 h of CO2 exposure and then gradually decreased.	Nitrogen	77-79	dopamine beta-hydroxylase	Cavia porcellus	142-167
6892785-2	1980	Helium and nitrogen increased the transition temperature by 0.021 and 0.006 degree C/atm, respectively, compared with 0.024 degrees C/atm for hydrostatic pressure.	Nitrogen	11-19	ATM serine/threonine kinase	Homo sapiens	85-88
6247710-1	1980	Myosin can be frozen in liquid nitrogen (-70 degrees C) and stored at this temperature for 5 months with no loss in K+, Ca2+, or actin + Mg2+ -stimulated ATPase activities.	Nitrogen	31-39	myosin heavy chain 14	Homo sapiens	0-6
486439-9	1979	Based on these results, it was infered that the formation of batho-rhodopsin is due to photoisomerization of the chromophoric retinal of rhodopsin and is not due to translocation of a proton on the ring or on the side chain from C-6 to C-8 of the chromophoric retinal to the Schiff-base nitrogen.	Nitrogen	287-295	rhodopsin	Bos taurus	67-76
476940-2	1979	Our results correlated well with those by the routine SMAC glucose oxidase/peroxidase 3-methyl-2-benzothiazolinone hydrazone-N,N-dimethylaniline method (y = 1.02x - 49.4; r = 0.99) and the glucose oxidase oxygen-rate method (y = 0.99x + 14; r = 0.99) with the Beckman Glucose Analyzer.	Nitrogen	125-126	diablo IAP-binding mitochondrial protein	Homo sapiens	54-58
20208831-5	1979	In this work we have treated the case of water vapor in N(2) at a total pressure of 1 atm.	Nitrogen	56-60	ATM serine/threonine kinase	Homo sapiens	86-89
718881-2	1978	Squid rhodopsin has positive CD bands at wavelengths corresponding the alpha- and beta-absorption bands at liquid nitrogen temperature (CD maxima: 485 nm at alpha-band and 348 nm at beta-band) as well as at room temperature (CD maxima: 474 nm at alpha-band and 347 nm at beta-band).	Nitrogen	114-122	rhodopsin	Bos taurus	6-15
664053-2	1978	The method is based on the capacity of Zn2+ and Co2+ to bind selectivity with sulphur and nitrogen atoms in bioligands.	Nitrogen	90-98	complement C2	Homo sapiens	48-51
20182-4	1977	These results, together with the earlier data, demonstrate that the three major nitrogen-containing classes of biomolecules could have originated from HCN on the primitive earth.	Nitrogen	80-88	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	151-154
560319-0	1977	[Effect of thyroxine and insulin on nitrogen metabolism in the gastrointestinal system and mammary glands of lactating cows].	Nitrogen	36-44	insulin	Bos taurus	25-32
560319-6	1977	Subcutaneous administration of thyroxin and insulin obviously increases the amount of protein, casein and nitrogen substances in the milk.	Nitrogen	106-114	insulin	Bos taurus	44-51
175064-7	1976	When microsomes were subjected to nitrogen cavitation, treatment with solium deoxycholate, or glutaraldehyde fixation, the Km of glucose-6-phosphatase for glucose-6 P decreased from approximately 6 mM to approximately 2.5 mM; the corresponding change in the Vmax ranged from-10% to +40%.	Nitrogen	34-42	glucose-6-phosphatase catalytic subunit 1	Rattus norvegicus	129-150
765685-1	1975	The activity and electrophoretic spectrum of glucose-6-phosphate dehydrogenase, alcohol dehydrogenase, and malate dehydrogenase in Saccharomyces cerevisiae 14 depended on the conditions of cultivation, i. e. the sources of carbon and their concentration, the content of nitrogen, and aeration of the medium.	Nitrogen	270-278	glucose-6-phosphate dehydrogenase	Saccharomyces cerevisiae S288C	45-78
17773192-0	1971	Mars: has nitrogen escaped?	Nitrogen	10-18	methionyl-tRNA synthetase 1	Homo sapiens	0-4
17773192-1	1971	If eddy mixing is about as effective on Mars as it is on Earth, then there seems to be less nitrogen present on Mars than we would expect if terrestrial-type outgassing were the source.	Nitrogen	92-100	methionyl-tRNA synthetase 1	Homo sapiens	112-116
16657550-6	1970	(c) The ability of light-grown leaves, previously placed in darkness under nitrogen to dissociate polyribosomes to monoribosomes, to form nitrate reductase activity again correlated with the level of reformed polyribosomes following transfer of the leaves back to light.	Nitrogen	75-83	nitrate reductase [NADH] 1	Zea mays	138-155
17833499-0	1970	Mars: is nitrogen present?	Nitrogen	9-17	methionyl-tRNA synthetase 1	Homo sapiens	0-4
17833499-1	1970	If the atmosphere is uniformly mixed, a mixing ratio of nitrogen to carbon dioxide of 5 percent is consistent with the observational data on the ultraviolet dayglow of Mars.	Nitrogen	56-64	methionyl-tRNA synthetase 1	Homo sapiens	168-172
13741389-9	1960	The presence of ferritin and apoferritin in the samples of hemosiderin granules was demonstrated by means of precipitin tests in agar-gel, using rabbit antiferritin sera with known antibody nitrogen concentrations.	Nitrogen	190-198	ferritin heavy chain 1	Homo sapiens	29-40
14435204-0	1959	[Quantitative distribution of nitrogen-fixing bacteria and their ecology in the Zernov phyllophora region of the Black Sea].	Nitrogen	30-38	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	119-122
13670113-0	1959	Notes on interferences by oxides of nitrogen with estimations of carbon monoxide in air by the NBS indicating tubes.	Nitrogen	36-44	nibrin	Homo sapiens	95-98
32930941-8	2021	Elevated nociceptin/OFQ (N/OFQ) levels observed in cerebrospinal fluid of SPS rats were even higher in SPS + SNP group.	Nitrogen	25-26	prepronociceptin	Rattus norvegicus	9-19
33780816-9	2021	Gas generated from anoxic reactor consisted of 91% nitrogen, 1% CO2, 1% H2S and rest was unaccounted.	Nitrogen	51-59	gastrin	Homo sapiens	0-3
34044169-4	2021	Particularly, the Ser/Thr-protein kinase PknG has gained relevance since it regulates nitrogen metabolism and facilitates bacterial survival inside macrophages.	Nitrogen	86-94	serine/threonine-protein kinase PknG	Mycobacterium tuberculosis H37Rv	41-45
33890594-11	2021	For the OER, the best performance was achieved with a derivative of 3, prepared by heating this compound in N2 at 200  C. This derivative showed overpotential (339 mV, at a current density of 10 mA cm-2) and Tafel slope (51.7 mV dec-1) values comparable to those of other Co2+ related materials.	Nitrogen	108-110	complement C2	Homo sapiens	272-275
33914523-0	2021	Dopant-Enriched Nitrogen Gas for Enhanced Electrospray Ionization of Released Glycans in Negative Ion Mode.	Nitrogen	16-24	gastrin	Homo sapiens	25-28
33914523-1	2021	The desolvation and ionization process of analytes can significantly be improved by enriching the nebulizing gas with a dopant (dopant enriched nitrogen (DEN) gas) in the electrospray source.	Nitrogen	144-152	gastrin	Homo sapiens	109-112
33914523-1	2021	The desolvation and ionization process of analytes can significantly be improved by enriching the nebulizing gas with a dopant (dopant enriched nitrogen (DEN) gas) in the electrospray source.	Nitrogen	144-152	gastrin	Homo sapiens	159-162
33914523-4	2021	Compared to the standard acetonitrile enriched nitrogen gas, isopropanol showed the highest increase in regards to peak areas.	Nitrogen	47-55	gastrin	Homo sapiens	56-59
33963081-8	2021	SnRK1 negatively regulates CO and FT transcript levels under high N conditions.	Nitrogen	66-67	PEBP (phosphatidylethanolamine-binding protein) family protein	Arabidopsis thaliana	34-36
33881323-3	2021	Highly stable nitrogen/water (N2/brine) foams are formed with CaCl2 concentrations up to 2% from 25 to 90  C. The viscoelastic gas-brine interface retards drainage of the lamellae, and the high dilational elasticity arrests coarsening (Ostwald ripening) with no observable change in foam bubble size over 48 h. The ability to design NP-laden viscoelastic interfaces for highly stable foams, even with high divalent ion concentrations, is of fundamental mechanistic interest for a broad range of foam applications and in particular foams for CO2 sequestration and enhanced oil recovery.	Nitrogen	14-22	complement C2	Homo sapiens	541-544
6420775-3	1983	The unambiguous assignment of the proton resonances was established by correlating with the C-13 NMR spectrum of the complex from [N-15]AMP, which showed a doublet for the C-1" carbon signal due to the spin coupling with N-15 (N-9).	Nitrogen	97-98	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	92-95
6130141-7	1982	The observed ratio of Ka1/Ka2 in I-III, 2.75 X 10(5)-7.76 X 10(5), was attributed to solven- and space-mediated field effects and electrostatic induction between nitrogen atoms in the piperazine ring.	Nitrogen	162-170	glutamate ionotropic receptor kainate type subunit 4	Homo sapiens	22-29
6982070-11	1982	HCN appears to bind to and be reduced at an enzyme state more oxidized than the one responsible for either H2 evolution or N2 reduction.	Nitrogen	123-125	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	0-3
6182073-6	1982	In rats given gentamicin (20 or 80 mg/kg/day, s.c.) for 10 days, serum beta 2-M was increased simultaneously with changes in common renal function parameters such as serum urea nitrogen, creatinine, and urinary protein.	Nitrogen	177-185	beta-2 microglobulin	Rattus norvegicus	71-79
7042346-1	1982	Saccharomyces cerevisiae mutants lacking the anabolic L-threonine deaminase, the ilv1- mutants, have been found to exhibit a normal ability to grow, without auxotrophy towards isoleucine, on L-threonine of L-serine as only nitrogen nutrient.	Nitrogen	223-231	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	81-85
7042346-2	1982	Starting from a strain carrying a ilv1- mutation, a new mutation affecting the ability to utilize L-threonine as nitrogen source was selected.	Nitrogen	113-121	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	34-38
6176268-8	1982	Of the agents tested, an N-substituted derivative of PS previously identified as an inhibitor of mast cell secretion was shown to be a particularly potent and efficacious inhibitor of mast cell phospholipase A2.	Nitrogen	25-26	phospholipase A2 group IB	Rattus norvegicus	194-210
7074421-6	1982	Therefore, it appears that if more nitrogen is excreted as ammonium, net protein breakdown increases to furnish the substrate for ammoniagenesis rather than reducing the excretion of the other nitrogenous waste component urea.	Nitrogen	35-43	solute carrier family 6 member 2	Rattus norvegicus	69-72
6762158-5	1982	Snap freezing of unprotected spermatozoa in liquid nitrogen yielded a fivefold increase in total acrosin activity, thus demonstrating that this is the method of choice for optimal acrosin extraction.	Nitrogen	51-59	acrosin	Homo sapiens	97-104
6762158-5	1982	Snap freezing of unprotected spermatozoa in liquid nitrogen yielded a fivefold increase in total acrosin activity, thus demonstrating that this is the method of choice for optimal acrosin extraction.	Nitrogen	51-59	acrosin	Homo sapiens	180-187
7261330-2	1981	Antisera raised to bovine serum albumin (BSA) conjugates of codeine-6-hemisuccinate, ethylmorphine-6-hemisuccinate, or oxycodone-6-carboxymethyloxime had greatest recognition of structural changes around the piperidine ring nitrogen atom and th 14-position.	Nitrogen	224-232	albumin	Canis lupus familiaris	26-39
7279985-0	1981	New N-substituted derivatives of E-2"- and E-3"- hydroxystilbazoles-(4) of potential antimicrobial activity.	Nitrogen	0-1	small nucleolar RNA, H/ACA box 63	Homo sapiens	43-46
7397132-0	1980	Circular dichroism of cattle rhodopsin and bathorhodopsin at liquid nitrogen temperatures.	Nitrogen	68-76	rhodopsin	Bos taurus	29-38
7397132-4	1980	The measurement of circular dichroism of rhodopsin extract (containing 66% or 75% of glycerol) at liquid nitrogen temperatures (-195 degrees C) by a conventional spectropolarimeter induced an extraordinary large signal, owing to linear dichroism originated from conversion of rhodopsin to bathorhodopsin by the measuring light.	Nitrogen	105-113	rhodopsin	Bos taurus	41-50
7372626-1	1980	Human antithrombin III has been shown to contain four identical N-glycosidically linked carbohydrate chain per molecule.	Nitrogen	64-65	serpin family C member 1	Homo sapiens	6-22
6244857-6	1980	Space-filling models revealed the possibility of a hydrogen bond between the oxygen of amide of residue-70 asparagine and the epsilon-amino nitrogen of residue-72 lysine in unmethylated horse heart cytochrome C.	Nitrogen	140-148	cytochrome c, somatic	Equus caballus	198-210
6989336-1	1980	When cells of the yeast, Saccharomyces cerevisiae, were deprived of nitrogen, a condition leading to G1 arrest, there was an immediate increase in the levels of total ribonuclease (RNase) activity within these cells.	Nitrogen	68-76	ribonuclease	Saccharomyces cerevisiae S288C	167-179
6989336-1	1980	When cells of the yeast, Saccharomyces cerevisiae, were deprived of nitrogen, a condition leading to G1 arrest, there was an immediate increase in the levels of total ribonuclease (RNase) activity within these cells.	Nitrogen	68-76	ribonuclease	Saccharomyces cerevisiae S288C	181-186
475464-0	1979	Effects of nitrogen dioxide on elastin and collagen contents of lung.	Nitrogen	11-19	Eln	Mesocricetus auratus	31-38
31491-3	1978	These results, together with the earlier data, demonstrate that the three main classes of nitrogen-containing biomolecules, purines, pyrimidines and amino acids may have originated from HCN on the primitive earth.	Nitrogen	90-98	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	186-189
84346-6	1978	N-acetylated metabolites of PAH were released at a 5 times higher rate by kidneys perfused with FC 43 than by HES-perfused organs.	Nitrogen	0-1	phenylalanine hydroxylase	Rattus norvegicus	28-31
404151-7	1977	It is proposed that copper is coordinated to the postulated pyridoxal phosphate of diamine oxidase through the pyridine nitrogen.	Nitrogen	120-128	amine oxidase copper containing 1	Sus scrofa	83-98
15835-10	1977	In contrast to cathepsin B1, its capability of hydrolyzing N-substituted derivatives of arginine is low and it does not split esters.	Nitrogen	59-60	cathepsin B	Rattus norvegicus	15-27
24271418-0	1976	Dopamine-beta-hydroxylase: Stimulation by nitrogen-containing heterocyclics and the role of catalase.	Nitrogen	42-50	dopamine beta-hydroxylase	Homo sapiens	0-25
9766-9	1976	Cathepsin L stored in presence of glutathion and EDTA in liquid nitrogen kept its activity for some months.	Nitrogen	64-72	cathepsin L	Rattus norvegicus	0-11
61140-8	1976	The unfavorable effects of glucagon on albumin and haptoglobin synthesis and on nitrogen balance were reversed by giving insulin simultaneously.	Nitrogen	80-88	insulin	Bos taurus	121-128
61140-9	1976	It is emphasized that insulin is essential for positive nitrogen balance.	Nitrogen	56-64	insulin	Bos taurus	22-29
1149902-8	1975	The stability of acrosin in acidic acrosomal extracts during liquid nitrogen freeze treatment was confirmed.	Nitrogen	68-76	acrosin	Homo sapiens	17-24
33349924-7	2021	CSF2 p.N44H results in disruption of one of the protein"s two N-glycosylation sites.	Nitrogen	7-8	colony stimulating factor 2	Homo sapiens	0-4
33512253-1	2021	6-hydroxykynurenic acid (6-HKA) is a nitrogen-containing phenolic acid compound in Ginkgo biloba leaves.	Nitrogen	37-45	ATPase H+/K+ transporting subunit alpha	Rattus norvegicus	27-30
33910203-8	2021	Challenging hMPO-immunized rats with the anti-GBM serum led to more glomerular neutrophil infiltration and MPO release, and severe haematuria, heavy proteinuria, and higher blood urea nitrogen than hMPO alone.	Nitrogen	184-192	myeloperoxidase	Rattus norvegicus	13-16
15264219-0	2004	Three putative N-glycosylation sites within the murine 5-HT3A receptor sequence affect plasma membrane targeting, ligand binding, and calcium influx in heterologous mammalian cells.	Nitrogen	15-16	5-hydroxytryptamine (serotonin) receptor 3A	Mus musculus	55-61
1055171-1	1975	Complement receptor activity for cell bound C3b and C3d was detected on plasma membrane fragments prepared by nitrogen cavitation from cultured human lymphoid cells.	Nitrogen	110-118	endogenous retrovirus group K member 13	Homo sapiens	52-55
15377272-1	2004	A comparative study of secondary specificities of enteropeptidase and trypsin was performed using peptide substrates with general formula A-(Asp/Glu)n-Lys(Arg)-(downward arrow)-B, where n = 1-4.	Nitrogen	27-28	transmembrane serine protease 15	Homo sapiens	50-65
1139004-2	1975	Substitution of methyl groups of the ammonium grouping with other radicals and incorporation of onium nitrogen in the cycle resulted in the decrease of the hydrolysis rate under the action of BCE and ACE, the effect of BCE being more pronounced.	Nitrogen	102-110	butyrylcholinesterase	Bos taurus	192-195
1139004-2	1975	Substitution of methyl groups of the ammonium grouping with other radicals and incorporation of onium nitrogen in the cycle resulted in the decrease of the hydrolysis rate under the action of BCE and ACE, the effect of BCE being more pronounced.	Nitrogen	102-110	butyrylcholinesterase	Bos taurus	219-222
15131261-2	2004	Based on the known expression of STC1 in theca/interstitial cells of the ovary, we generated recombinant N-glycosylated STC1 protein and tested its ability to modulate granulosa cell differentiation.	Nitrogen	105-106	stanniocalcin 1	Homo sapiens	33-37
4519646-2	1973	The translocated N-acetyl-Phe-tRNA, bound to the ribosomal donor site, prevents further interaction of EF-G with the ribosome, for it inhibits the GTP hydrolysis that takes place in the presence of EF-G and ribosomes and it decreases the formation of either the GDP.EF-G.fusidic acid.ribosome complex or the 5"-guanylylmethylenediphosphonate.EF-G.ribosome complex.	Nitrogen	17-18	G elongation factor mitochondrial 1	Homo sapiens	103-107
4519646-2	1973	The translocated N-acetyl-Phe-tRNA, bound to the ribosomal donor site, prevents further interaction of EF-G with the ribosome, for it inhibits the GTP hydrolysis that takes place in the presence of EF-G and ribosomes and it decreases the formation of either the GDP.EF-G.fusidic acid.ribosome complex or the 5"-guanylylmethylenediphosphonate.EF-G.ribosome complex.	Nitrogen	17-18	G elongation factor mitochondrial 1	Homo sapiens	198-202
4519646-2	1973	The translocated N-acetyl-Phe-tRNA, bound to the ribosomal donor site, prevents further interaction of EF-G with the ribosome, for it inhibits the GTP hydrolysis that takes place in the presence of EF-G and ribosomes and it decreases the formation of either the GDP.EF-G.fusidic acid.ribosome complex or the 5"-guanylylmethylenediphosphonate.EF-G.ribosome complex.	Nitrogen	17-18	G elongation factor mitochondrial 1	Homo sapiens	198-202
4519646-2	1973	The translocated N-acetyl-Phe-tRNA, bound to the ribosomal donor site, prevents further interaction of EF-G with the ribosome, for it inhibits the GTP hydrolysis that takes place in the presence of EF-G and ribosomes and it decreases the formation of either the GDP.EF-G.fusidic acid.ribosome complex or the 5"-guanylylmethylenediphosphonate.EF-G.ribosome complex.	Nitrogen	17-18	G elongation factor mitochondrial 1	Homo sapiens	198-202
15131261-2	2004	Based on the known expression of STC1 in theca/interstitial cells of the ovary, we generated recombinant N-glycosylated STC1 protein and tested its ability to modulate granulosa cell differentiation.	Nitrogen	105-106	stanniocalcin 1	Homo sapiens	120-124
15235595-4	2004	From X-ray and Raman scattering we have identified this as the long-sought-after polymeric nitrogen with the theoretically predicted cubic gauche structure (cg-N).	Nitrogen	91-99	cingulin	Homo sapiens	157-161
4353692-1	1973	Enterotoxin produced by a sporulating culture of Clostridium perfringens type A NCTC 8798 was purified to a level of 3,500 mouse mean lethal doses per mg of nitrogen.	Nitrogen	157-165	cpe	Clostridium perfringens	0-11
4401118-0	1972	Influence of level and source of nitrogen intake on liver glutamine synthetase activity in the chick.	Nitrogen	33-41	glutamate-ammonia ligase	Gallus gallus	58-78
15235595-8	2004	The cg-N represents a new class of single-bonded nitrogen materials with unique properties such as energy capacity: more than five times that of the most powerfully energetic materials.	Nitrogen	49-57	cingulin	Homo sapiens	4-8
5299011-0	1967	Total protein and total nitrogen in gastrin-stimulated gastric secretion of man.	Nitrogen	24-32	gastrin	Homo sapiens	36-43
5925292-0	1966	[The effect of somatotropin from cattle pituitaries on the levels of proteins and alpha-amino nitrogen of blood plasma and of free amino acids in whole blood].	Nitrogen	94-102	somatotropin	Bos taurus	15-27
15236576-10	2004	Most striking, however, is the presence in the C271A mutant crystallographic structure of a chloride ion within 3.5 A of the nonreactive N(eta) substrate nitrogen, approximating the position of the sulfur in the wild-type"s cysteine.	Nitrogen	154-162	endothelin receptor type A	Homo sapiens	139-142
13825435-0	1959	[On the significance of the position of quaternary nitrogen atom in the molecule of certain substances in their reactive capacity with true and false cholinesterase].	Nitrogen	51-59	butyrylcholinesterase	Homo sapiens	150-165
15294089-6	2004	It was found that an N-glycosylation consensus site of the J-chain was functional, and intracellular J-chain was endoglycosidase H sensitive.	Nitrogen	21-22	joining chain of multimeric IgA and IgM	Homo sapiens	59-66
33749955-1	2021	BACKGROUND: There have been concerns about the increased use of helium and nitrogen gas as a suicide mechanism in Australia.	Nitrogen	75-83	gastrin	Homo sapiens	84-87
33749955-9	2021	Compared to individuals using other non-carbon monoxide gases, individuals who died by suicide from helium or nitrogen were significantly more likely to be older, have a physical illness and/or disability, have contacted a euthanasia group and have accessed instructional material and purchased gas online.	Nitrogen	110-118	gastrin	Homo sapiens	56-59
33749955-10	2021	CONCLUSIONS: Suicides by carbon monoxide decreased between 2006 and 2017 alongside an increase in argon and nitrogen gas use - particularly among older adults.	Nitrogen	108-116	gastrin	Homo sapiens	117-120
15239850-1	2004	The nitrogen mustards bis(2-chloroethyl)ethylamine (HN1), bis(2-chloroethyl)methylamine (HN2), and tris(2-chloroethyl)amine (HN3) have the potential to be used as chemical terrorism agents because of their extreme vesicant properties.	Nitrogen	4-12	Jupiter microtubule associated homolog 1	Homo sapiens	52-55
15158379-3	2004	The nitrogen BET surface is overestimated on the pure silica sample and underestimated for the polymer-coated sample.	Nitrogen	4-12	delta/notch like EGF repeat containing	Homo sapiens	13-16
15210806-6	2004	Additionally, ICAM-1 KO mice mounted an unimpaired IFN-gamma response and IFN-gamma-dependent production of reactive nitrogen intermediates and parasite- specific IgG2a.	Nitrogen	117-125	intercellular adhesion molecule 1	Mus musculus	14-20
15209499-6	2004	The active site Ni geometry cycles from square planar Ni(II), with thiolate (Cys2 and Cys6) and backbone nitrogen (His1 and Cys2) ligands, to square pyramidal Ni(III) with an added axial His1 side chain ligand, consistent with electron paramagentic resonance spectroscopy.	Nitrogen	105-113	viral integration site 1	Homo sapiens	115-119
15183061-2	2004	We investigated the role of N-linked glycosylation in the N-terminus of CXCR4 in binding to HIV-1 gp120 envelope glycoproteins.	Nitrogen	28-29	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	98-103
15183061-3	2004	Gp120s from CXCR4 (X4) and CCR5 (R5) using HIV-1 strains bound more efficiently to non-N-glycosylated than to N-glycosylated CXCR4 proteoliposomes in a CD4-dependent manner.	Nitrogen	87-88	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	0-5
15183061-3	2004	Gp120s from CXCR4 (X4) and CCR5 (R5) using HIV-1 strains bound more efficiently to non-N-glycosylated than to N-glycosylated CXCR4 proteoliposomes in a CD4-dependent manner.	Nitrogen	110-111	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	0-5
15183061-8	2004	These findings demonstrate that N-glycosylation at N11 inhibits the binding of CXCR4 to X4 and R5 HIV-1 gp120, and provide a better understanding of the structural elements of CXCR4 involved in HIV-1 Env-co-receptor interactions.	Nitrogen	32-33	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	104-109
15157999-3	2004	TCDD suppressed DNA synthesis of SK-N-SH human neuronal cells determined by [(3)H]thymidine incorporation which was significantly prevented either by pretreatment with alpha-naphthoflavone (alpha-NF), a partial AhR antagonist, or 8-methoxypsoralen (MOP), a binding inhibitor of activated AhR to dioxin response elements.	Nitrogen	35-37	aryl hydrocarbon receptor	Homo sapiens	211-214
33904933-10	2021	12G5A antibody recognized the N-linked glycosylation epitope on annexin A2.	Nitrogen	30-31	annexin A2	Homo sapiens	64-74
33884581-9	2021	Overall, these results reveal an additional therapeutic mechanism of action of clozapine: this drug posttranslationally inhibits the degradation of Arg/N-degron substrates, including RGS4.	Nitrogen	152-153	regulator of G-protein signaling 4	Rattus norvegicus	183-187
15169885-6	2004	(i) We demonstrate that depletion of glucose and nitrogen leads to a transient replacement of the histone deacetylase (HDAC) complex on the promoters of EMG by the transcriptional activator Ime1.	Nitrogen	49-57	transcription factor IME1	Saccharomyces cerevisiae S288C	190-194
33857304-1	2021	Gln3 activates Nitrogen Catabolite Repression, NCR-sensitive expression of the genes required for Saccharomyces cerevisiae to scavenge poor nitrogen sources from its environment.	Nitrogen	15-23	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
15215512-9	2004	Taken together, our results suggest the existence of a GS1/AS pathway representing a metabolic route for transferring ammonium released from protein catabolism into asparagine, an amino acid that may have a major role in nitrogen mobilization from diseased tissues.	Nitrogen	221-229	glutamine synthetase	Solanum lycopersicum	55-58
33857304-1	2021	Gln3 activates Nitrogen Catabolite Repression, NCR-sensitive expression of the genes required for Saccharomyces cerevisiae to scavenge poor nitrogen sources from its environment.	Nitrogen	140-148	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
15146521-0	2004	Road maps for nitrogen-transfer catalysis: the challenge of the osmium(VIII)-catalyzed diamination.	Nitrogen	14-22	cytochrome c oxidase subunit 8A	Homo sapiens	71-75
33721816-8	2021	The developed platform mentioned above facilitated rapid identification of four alpha-glucosidase inhibitors, namely, N-p-trans-coumaroyltyramine (1), N-trans-caffeoyl-tyramine (2), (9R,10E,12Z)-9-hydroxy-10,12-octadecadienoic acid (3a), and (9S,10E,12Z)-9-hydroxy-10,12-octadecadienoic acid (3b) from Cortex Lycii.	Nitrogen	118-120	sucrase-isomaltase	Homo sapiens	80-97
15078947-5	2004	E7 lacks the N-terminal p300-binding region present in E1A.	Nitrogen	13-14	E1A binding protein p300	Homo sapiens	24-28
33168291-0	2021	A novel strategy for sequential reduction of nitrate into nitrogen by CO2 anion radical: Experimental study and DFT calculation.	Nitrogen	58-66	complement C2	Homo sapiens	70-73
15133116-6	2004	The ilv2 mutants were auxotrophic for isoleucine and valine and the auxotrophy was satisfied by these amino acids only when proline, and not ammonium, was the nitrogen source, indicating nitrogen regulation of amino acid transport.	Nitrogen	159-167	acetolactate synthase catalytic subunit	Saccharomyces cerevisiae S288C	4-8
34012659-11	2021	We also observed the increased ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3), which is trimming of N-linked glycans by sequential removal of mannose residues, might result in more non-N-glycosylated form of BST-2.	Nitrogen	119-120	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	31-88
34012659-11	2021	We also observed the increased ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3), which is trimming of N-linked glycans by sequential removal of mannose residues, might result in more non-N-glycosylated form of BST-2.	Nitrogen	119-120	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	90-95
32677746-3	2021	Analyses of mucin-type core-1 O-glycoform of apolipoprotein C-III (apoCIII) have recently revealed combined N- and O-glycosylation defects.	Nitrogen	108-109	apolipoprotein C3	Homo sapiens	45-65
32677746-3	2021	Analyses of mucin-type core-1 O-glycoform of apolipoprotein C-III (apoCIII) have recently revealed combined N- and O-glycosylation defects.	Nitrogen	108-109	apolipoprotein C3	Homo sapiens	67-74
32677746-7	2021	B4GALT1- and TRAPPC11-CDG were accompanied by under-sialylation of O-glycans and are now recognized as combined N- and O-glycosylation disorders.	Nitrogen	112-113	beta-1,4-galactosyltransferase 1	Homo sapiens	0-7
32677746-7	2021	B4GALT1- and TRAPPC11-CDG were accompanied by under-sialylation of O-glycans and are now recognized as combined N- and O-glycosylation disorders.	Nitrogen	112-113	trafficking protein particle complex subunit 11	Homo sapiens	13-21
15133116-6	2004	The ilv2 mutants were auxotrophic for isoleucine and valine and the auxotrophy was satisfied by these amino acids only when proline, and not ammonium, was the nitrogen source, indicating nitrogen regulation of amino acid transport.	Nitrogen	187-195	acetolactate synthase catalytic subunit	Saccharomyces cerevisiae S288C	4-8
33500062-5	2021	The quantitative and qualitative output of MEF is significantly affected by: (a) conditions of the process in the reactor: the gas pressure, its flow rate, temperature, amperage; the distance between the electrodes, and others, that is, those factors that determine the plasma temperature and the residence time of the reaction particles in it; (b) the composition of solid additives (salts, oxides, metal alloys) in the graphite anode and their quantitative (mol) ratio with carbon; (c) replacement of the inert atmosphere of the synthesis with the active one (helium-with nitrogen, ammonia, water vapor, CO and other gases).	Nitrogen	574-582	E74 like ETS transcription factor 4	Homo sapiens	43-46
15069543-0	2004	Regulatory roles of N-glycosylation of immunoglobulin M in CD40-CD40L-mediated cell survival of human diffuse large B cell lymphoma.	Nitrogen	20-21	CD40 molecule	Homo sapiens	59-63
15069543-11	2004	From the present results it is possible that reduction of N-glycosylation of the heavy chain of IgM by SW treatment may reduce anti-IgM-induced growth inhibition, and reduction in anti-IgM-induced growth inhibition due to altered N-glycosylation may enhance CD40-CD40L-mediated cell survival through TRAF2 which interacts with both IgM and CD40 in HBL-2 cells.	Nitrogen	58-59	CD40 molecule	Homo sapiens	258-262
33841473-8	2021	Besides, activities of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) were increased, whereas the content of malondialdehyde (MDA) declined under foliar nitrogen application (especially NH4 +-N).	Nitrogen	171-179	catalase-1	Triticum aestivum	73-81
15069543-11	2004	From the present results it is possible that reduction of N-glycosylation of the heavy chain of IgM by SW treatment may reduce anti-IgM-induced growth inhibition, and reduction in anti-IgM-induced growth inhibition due to altered N-glycosylation may enhance CD40-CD40L-mediated cell survival through TRAF2 which interacts with both IgM and CD40 in HBL-2 cells.	Nitrogen	58-59	CD40 molecule	Homo sapiens	263-267
33841473-8	2021	Besides, activities of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) were increased, whereas the content of malondialdehyde (MDA) declined under foliar nitrogen application (especially NH4 +-N).	Nitrogen	171-179	catalase-1	Triticum aestivum	83-86
15047148-4	2004	When N-glycosylation was prevented through point mutations in N-glycosylation sites in CD28, or reduced by glycosidase inhibitors, the binding of CD28 to CD80 significantly increased.	Nitrogen	62-63	CD80 molecule	Homo sapiens	154-158
15047148-9	2004	The results support the hypothesis that the N-glycosylation negatively regulates CD28-mediated T cell adhesion and costimulation.	Nitrogen	44-45	CD28 molecule	Homo sapiens	81-85
33616385-2	2021	Each product contains a positively charged trimethylammonioethenyl ligand, CH CH(+NMe3), that is derived from a 2-trimethylammonioethenide, -CH CH(+NMe3), zwitterion that formally has a positive charge on the nitrogen atom and a negative charge on the terminal enyl carbon atom.	Nitrogen	209-217	NME/NM23 nucleoside diphosphate kinase 3	Homo sapiens	82-86
14761979-4	2004	We performed a differential screen on wild-type and Deltaatg7/apg7 autophagy-deficient cells and found that cytosolic acetaldehyde dehydrogenase (Ald6p) decreased under nitrogen starvation.	Nitrogen	169-177	aldehyde dehydrogenase (NADP(+)) ALD6	Saccharomyces cerevisiae S288C	146-151
33220957-2	2021	Herein, nitrogen-deficient CN homojunctions were simply synthesized by calcining dicyandiamide-loaded CN (prepared from urea and denoted as UCN) with dicyandiamide polymerizing into CN (denoted as DCN) and simultaneous formation of nitrogen vacancies in the surface of UCN.	Nitrogen	8-16	urocortin	Homo sapiens	140-143
33220957-2	2021	Herein, nitrogen-deficient CN homojunctions were simply synthesized by calcining dicyandiamide-loaded CN (prepared from urea and denoted as UCN) with dicyandiamide polymerizing into CN (denoted as DCN) and simultaneous formation of nitrogen vacancies in the surface of UCN.	Nitrogen	8-16	urocortin	Homo sapiens	269-272
33169272-3	2021	This study focused on the effects of the induced inflammation by IL-1ss in compressed human periodontal ligament fibroblasts (HPdLF) exposed to the nitrogen-containing BP zoledronate in vitro.	Nitrogen	148-156	interleukin 1 alpha	Homo sapiens	65-69
14761979-5	2004	As assessed by immunoblot, Ald6p was reduced by greater than 82% after 24 h of nitrogen starvation.	Nitrogen	79-87	aldehyde dehydrogenase (NADP(+)) ALD6	Saccharomyces cerevisiae S288C	27-32
34045715-4	2021	The bridging [MoFe3S4]2(mu-eta1:eta1-N2) complex thus prepared features a substantially weakened N-N bond despite the relatively high formal oxidation states of the metal centres.	Nitrogen	37-38	secreted phosphoprotein 1	Homo sapiens	27-31
33660202-9	2021	Increased glutamate N-methyl-D-aspartate (NMDA) receptor subunits 2B (GluN2B) and phosphorylated-ERK1/2 were seen in the mPFC, striatum, and hippocampus of IH mice, but no significant microglial and astrocyte activation was found in these brain areas.	Nitrogen	20-22	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	70-76
34045715-4	2021	The bridging [MoFe3S4]2(mu-eta1:eta1-N2) complex thus prepared features a substantially weakened N-N bond despite the relatively high formal oxidation states of the metal centres.	Nitrogen	37-38	secreted phosphoprotein 1	Homo sapiens	32-36
14761979-10	2004	Ald6p enzymatic activity may be disadvantageous for survival under nitrogen starvation; therefore, yeast cells may preferentially eliminate Ald6p via autophagy.	Nitrogen	67-75	aldehyde dehydrogenase (NADP(+)) ALD6	Saccharomyces cerevisiae S288C	0-5
34045715-4	2021	The bridging [MoFe3S4]2(mu-eta1:eta1-N2) complex thus prepared features a substantially weakened N-N bond despite the relatively high formal oxidation states of the metal centres.	Nitrogen	97-98	secreted phosphoprotein 1	Homo sapiens	27-31
15047036-6	2004	In multivariable Cox regression models, the risk of all-cause mortality increased with each quartile of blood urea nitrogen, with an adjusted relative risk of 2.3 in patients in the upper compared with the lower quartiles (95% confidence interval [CI]: 1.3 to 4.1; P = 0.005).	Nitrogen	115-123	cytochrome c oxidase subunit 8A	Homo sapiens	17-20
34045715-4	2021	The bridging [MoFe3S4]2(mu-eta1:eta1-N2) complex thus prepared features a substantially weakened N-N bond despite the relatively high formal oxidation states of the metal centres.	Nitrogen	97-98	secreted phosphoprotein 1	Homo sapiens	32-36
34051264-5	2021	Exo-srIkB treatment resulted in lower levels of serum blood urea nitrogen, creatinine, and neutrophil gelatinase-associated lipocalin in post-ischemic mice than in the Exo-Naive treatment group.	Nitrogen	65-73	5'-3' exoribonuclease 1	Mus musculus	0-3
33963398-0	2021	Thioredoxin m overexpression in chloroplasts alters carbon and nitrogen partitioning in tobacco plants.	Nitrogen	63-71	thioredoxin H-type 1	Nicotiana tabacum	0-11
33522808-0	2021	HMNTA Complexes of Tetravalent Metal Ions: On the Roles of Carbonyl Oxygen and Amine Nitrogen in the Stabilization of Gas-Phase M(HMNTA)24+ Complexes.	Nitrogen	85-93	gastrin	Homo sapiens	118-121
32926180-0	2021	Differential effects of putative N-glycosylation sites in human Tau on Alzheimer"s disease-related neurodegeneration.	Nitrogen	33-34	microtubule associated protein tau	Homo sapiens	64-67
32926180-3	2021	N-glycosylated Tau was reported to be found in AD brain tissues but not in healthy counterparts.	Nitrogen	0-1	microtubule associated protein tau	Homo sapiens	15-18
32926180-5	2021	Previous in vitro studies indicated that N-glycosylation of Tau facilitated its phosphorylation and contributed to maintenance of its Paired Helical Filament structure.	Nitrogen	41-42	microtubule associated protein tau	Homo sapiens	60-63
32926180-6	2021	However, the specific Tau residue(s) that undergo N-glycosylation and their effect on Tau-engendered pathology are unknown.	Nitrogen	50-51	microtubule associated protein tau	Homo sapiens	22-25
32926180-7	2021	High-performance liquid chromatography and mass spectrometry (LC-MS) analysis indicated that both N359 and N410 were N-glycosylated in wild-type (WT) human Tau (hTau) expressed in human SH-SY5Y cells.	Nitrogen	98-99	microtubule associated protein tau	Homo sapiens	156-159
32926180-7	2021	High-performance liquid chromatography and mass spectrometry (LC-MS) analysis indicated that both N359 and N410 were N-glycosylated in wild-type (WT) human Tau (hTau) expressed in human SH-SY5Y cells.	Nitrogen	98-99	microtubule associated protein tau	Homo sapiens	161-165
32926180-8	2021	Asparagine to glutamine mutants, which cannot undergo N-glycosylation, at each of three putative N-glycosylation sites in hTau (N167Q, N359Q, and N410Q) were generated and expressed in SH-SY5Y cells and in transgenic Drosophila.	Nitrogen	97-98	microtubule associated protein tau	Homo sapiens	122-126
33963398-2	2021	In the present work, the influence of thioredoxin (Trx) m on C and N partitioning was studied using tobacco plants overexpressing Trx m from the chloroplast genome.	Nitrogen	67-68	thioredoxin H-type 1	Nicotiana tabacum	38-49
33963398-2	2021	In the present work, the influence of thioredoxin (Trx) m on C and N partitioning was studied using tobacco plants overexpressing Trx m from the chloroplast genome.	Nitrogen	67-68	thioredoxin H-type 1	Nicotiana tabacum	51-54
33963398-6	2021	Moreover, higher photorespiration and nitrate accumulation were determined in these plants relative to the untransformed control, indicating that overexpression of Trx m favors the photorespiratory N cycle rather than primary nitrate assimilation.	Nitrogen	198-199	thioredoxin H-type 1	Nicotiana tabacum	164-167
32041489-8	2021	OleA was found to interact with the N-terminal domain of alpha-synuclein, making this region unavailable for interaction with membranes and lipids for the formation of cellular toxic aggregates.	Nitrogen	36-37	synuclein alpha	Homo sapiens	57-72
15013842-7	2004	We then determined the relative activity factor of each recombinant UGT and estimated the contribution of each UGT isoform to the N-glucosidation in human liver microsomes.	Nitrogen	130-131	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	111-114
31532899-4	2021	Surface and interface engineering have shown bright prospects to construct highly efficient Mox C-based electrocatalysts for energy conversion including the hydrogen evolution reaction, oxygen evolution reaction, nitrogen reduction reaction, and carbon dioxide reduction reaction.	Nitrogen	213-221	monooxygenase DBH like 1	Homo sapiens	92-95
33978735-3	2021	The human Gb3/CD77 synthase contains two occupied N-glycosylation sites at positions N121 and N203.	Nitrogen	50-51	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	10-13
33978735-3	2021	The human Gb3/CD77 synthase contains two occupied N-glycosylation sites at positions N121 and N203.	Nitrogen	50-51	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	14-27
33978735-5	2021	The fully N-glycosylated human Gb3/CD77 synthase and its glycoform missing the N121 glycan correctly localized in the Golgi, whereas a glycoform without the N203 site partially mislocalized in the endoplasmic reticulum.	Nitrogen	10-11	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	31-34
15126393-6	2004	Although cells growing under poor nitrogen-supply conditions display much higher induction of AGP1 expression than cells growing under good nitrogen-supply conditions, the UAS(AA) itself is totally insensitive to nitrogen availability.	Nitrogen	34-42	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	94-98
33978735-5	2021	The fully N-glycosylated human Gb3/CD77 synthase and its glycoform missing the N121 glycan correctly localized in the Golgi, whereas a glycoform without the N203 site partially mislocalized in the endoplasmic reticulum.	Nitrogen	10-11	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	35-48
33978735-8	2021	Taken together, our findings show that the two N-glycans of human Gb3/CD77 synthase have opposing effects on its properties, revealing a dual nature of N-glycosylation and potentially a novel regulatory mechanism controlling the biological activity of proteins.	Nitrogen	47-48	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	66-69
33978735-8	2021	Taken together, our findings show that the two N-glycans of human Gb3/CD77 synthase have opposing effects on its properties, revealing a dual nature of N-glycosylation and potentially a novel regulatory mechanism controlling the biological activity of proteins.	Nitrogen	47-48	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	70-83
33732275-9	2021	We concluded that these four conserved residues are indispensable as changes of all these residues together resulted in a subtle conformational change of CYP38 and reduced its intramolecular N-C interaction and the ability to associate with the thylakoid membrane, thus impairing its function in chloroplast.	Nitrogen	191-192	cyclophilin 38	Arabidopsis thaliana	154-159
33624829-4	2021	The mtETC produces reactive oxygen and nitrogen species, which can act as signals or lead to cellular damage, and are thus efficiently removed by mitochondrial antioxidant systems, including Mn-superoxide dismutase, ascorbate-glutathione cycle and thioredoxin-dependent peroxidases.	Nitrogen	39-47	thioredoxin	Homo sapiens	248-259
33900073-5	2021	Activities of key enzymes including sucrose synthase (SS), sucrose phosphate synthase (SPS) and phosphoenolpyruvate carboxylase (PEPC) that are involved in the carbon metabolism, and nitrate reductase (NR), glutamine synthetase (GS), and glutamate synthetase (GOGAT) that are involved in N metabolism, were all upregulated by 100 mg/L MWCNTs, which contributed to the increase of the accumulation of carbohydrates (sugar and starch), soluble protein, and N in plants.	Nitrogen	202-203	MLO-like protein 4	Zea mays	129-133
15126393-7	2004	Nitrogen-source control of AGP1 induction is mediated by the GATA factor Gln3, likely acting through adjacent 5"-GATA-3" sequences, to amplify the positive effect of UAS(AA).	Nitrogen	0-8	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	27-31
33900073-5	2021	Activities of key enzymes including sucrose synthase (SS), sucrose phosphate synthase (SPS) and phosphoenolpyruvate carboxylase (PEPC) that are involved in the carbon metabolism, and nitrate reductase (NR), glutamine synthetase (GS), and glutamate synthetase (GOGAT) that are involved in N metabolism, were all upregulated by 100 mg/L MWCNTs, which contributed to the increase of the accumulation of carbohydrates (sugar and starch), soluble protein, and N in plants.	Nitrogen	202-203	nitrate reductase [NADH] 1	Zea mays	183-200
33900073-5	2021	Activities of key enzymes including sucrose synthase (SS), sucrose phosphate synthase (SPS) and phosphoenolpyruvate carboxylase (PEPC) that are involved in the carbon metabolism, and nitrate reductase (NR), glutamine synthetase (GS), and glutamate synthetase (GOGAT) that are involved in N metabolism, were all upregulated by 100 mg/L MWCNTs, which contributed to the increase of the accumulation of carbohydrates (sugar and starch), soluble protein, and N in plants.	Nitrogen	288-289	MLO-like protein 4	Zea mays	96-127
33900073-5	2021	Activities of key enzymes including sucrose synthase (SS), sucrose phosphate synthase (SPS) and phosphoenolpyruvate carboxylase (PEPC) that are involved in the carbon metabolism, and nitrate reductase (NR), glutamine synthetase (GS), and glutamate synthetase (GOGAT) that are involved in N metabolism, were all upregulated by 100 mg/L MWCNTs, which contributed to the increase of the accumulation of carbohydrates (sugar and starch), soluble protein, and N in plants.	Nitrogen	288-289	MLO-like protein 4	Zea mays	129-133
33847125-3	2021	Here we report the first example of an N2-bridged rhenium(III) complex, [(trans-P2tBuPyrr)ReCl2]2(mu-eta1:eta1-N2) (P2tBuPyrr = [2,5-(CH2PtBu2)2C4H2N]-).	Nitrogen	39-41	secreted phosphoprotein 1	Homo sapiens	101-105
33847125-3	2021	Here we report the first example of an N2-bridged rhenium(III) complex, [(trans-P2tBuPyrr)ReCl2]2(mu-eta1:eta1-N2) (P2tBuPyrr = [2,5-(CH2PtBu2)2C4H2N]-).	Nitrogen	39-41	secreted phosphoprotein 1	Homo sapiens	106-110
33847125-3	2021	Here we report the first example of an N2-bridged rhenium(III) complex, [(trans-P2tBuPyrr)ReCl2]2(mu-eta1:eta1-N2) (P2tBuPyrr = [2,5-(CH2PtBu2)2C4H2N]-).	Nitrogen	111-113	secreted phosphoprotein 1	Homo sapiens	101-105
33619857-1	2021	Gut microorganisms metabolize azobenzene compounds (Ph1-N=N-Ph2) into free aniline products (Ph1-NH2 + H2N-Ph2), a process that has been largely investigated to reduce dyes residues in the textile industry.	Nitrogen	56-57	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	52-55
33619857-1	2021	Gut microorganisms metabolize azobenzene compounds (Ph1-N=N-Ph2) into free aniline products (Ph1-NH2 + H2N-Ph2), a process that has been largely investigated to reduce dyes residues in the textile industry.	Nitrogen	56-57	alanine--glyoxylate and serine--pyruvate aminotransferase	Homo sapiens	93-96
33668455-9	2021	Torlon/DES-5 demonstrates high selectivity in the gas separation of O2/N2 mixture.	Nitrogen	71-73	gastrin	Homo sapiens	50-53
33847125-3	2021	Here we report the first example of an N2-bridged rhenium(III) complex, [(trans-P2tBuPyrr)ReCl2]2(mu-eta1:eta1-N2) (P2tBuPyrr = [2,5-(CH2PtBu2)2C4H2N]-).	Nitrogen	111-113	secreted phosphoprotein 1	Homo sapiens	106-110
15125467-8	2004	RESULTS: The GLP-2 infusions resulted in a dose-dependent increase in antral emptying time (35%; ns and 75%; P = 0.049) compared to saline, but GLP-2 was less potent than GLP-1, which increased the antral emptying time by 192% (P &lt; 0.001).	Nitrogen	26-28	glucagon like peptide 1 receptor	Homo sapiens	171-176
33974913-6	2021	We implicate Ubr1, an E3 of the Arg/N-degron pathway, in targeting mitochondrial proteins processed by the mitochondrial inner membrane protease.	Nitrogen	36-37	E3 ubiquitin-protein ligase UBR1	Saccharomyces cerevisiae S288C	13-17
15031507-1	2004	A transect of 68 acid grasslands across Great Britain, covering the lower range of ambient annual nitrogen deposition in the industrialized world (5 to 35 kg Nha-1 year-1), indicates that long-term, chronic nitrogen deposition has significantly reduced plant species richness.	Nitrogen	207-215	solute carrier family 9 member B1	Homo sapiens	158-163
33592328-3	2021	The immunomodulatory capacity of BPs has been focused on the mechanisms involved in the acute-phase response associated with the administration of nitrogen containing BPs (N-BPs), with the stimulus of pro-inflammatory cytokines, through the mevalonate pathway, activation of T-cells and the decrease in the cytotoxic T-lymphocyte antigen-4 (CTLA-4).	Nitrogen	147-155	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	307-339
33592328-3	2021	The immunomodulatory capacity of BPs has been focused on the mechanisms involved in the acute-phase response associated with the administration of nitrogen containing BPs (N-BPs), with the stimulus of pro-inflammatory cytokines, through the mevalonate pathway, activation of T-cells and the decrease in the cytotoxic T-lymphocyte antigen-4 (CTLA-4).	Nitrogen	147-155	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	341-347
15031507-2	2004	Species richness declines as a linear function of the rate of inorganic nitrogen deposition, with a reduction of one species per 4-m2 quadrat for every 2.5 kg Nha-1 year-1 of chronic nitrogen deposition.	Nitrogen	72-80	solute carrier family 9 member B1	Homo sapiens	159-164
15031507-2	2004	Species richness declines as a linear function of the rate of inorganic nitrogen deposition, with a reduction of one species per 4-m2 quadrat for every 2.5 kg Nha-1 year-1 of chronic nitrogen deposition.	Nitrogen	183-191	solute carrier family 9 member B1	Homo sapiens	159-164
15031507-4	2004	At the mean chronic nitrogen deposition rate of central Europe (17 kg Nha-1 year-1), there is a 23% species reduction compared with grasslands receiving the lowest levels of nitrogen deposition.	Nitrogen	20-28	solute carrier family 9 member B1	Homo sapiens	70-75
14978164-10	2004	Deletion of either N- or O-linked glycosylation sites abrogated IgA1 binding to TfR, suggesting that sugars are essential for IgA1 binding.	Nitrogen	19-20	transferrin receptor	Homo sapiens	80-83
15006708-6	2004	Our findings suggest that, although the UPR is active in fibroblasts from FAD patients, mutant PS1 may selectively increase Abeta42 secretion when N-glycosylation is impaired.	Nitrogen	147-148	presenilin 1	Homo sapiens	95-98
14571263-1	2004	A late infantile metachromatic leukodystrophy patient was found to be heterozygous for the arylsulfatase A (ARSA) pseudodeficiency (pd) polyadenylation site variant ((*)96A&gt;G) in the absence of the commonly associated N-glycosylation site variant (N350S).	Nitrogen	221-222	arylsulfatase A	Homo sapiens	91-106
14571263-1	2004	A late infantile metachromatic leukodystrophy patient was found to be heterozygous for the arylsulfatase A (ARSA) pseudodeficiency (pd) polyadenylation site variant ((*)96A&gt;G) in the absence of the commonly associated N-glycosylation site variant (N350S).	Nitrogen	221-222	arylsulfatase A	Homo sapiens	108-112
14729038-5	2004	Computer simulations combined with fitting of simulated to the experimental ssb intensities result in the determination of precise values for the 14N quadrupole coupling (C(Q)) and its associated asymmetry parameter (eta(Q)) for the nitrogen sites in these molecules.	Nitrogen	233-241	endothelin receptor type A	Homo sapiens	217-220
14968425-1	2004	We have found that proline and the toxic proline analogue azetidine-2-carboxylate (AzC) are efficiently imported into Saccharomyces cerevisiae cells by four amino acid permeases, including two nitrogen-regulated permeases (PUT4 and GAP1) and two permeases that are regulated by the SPS sensor of extracellular amino acids (AGP1 and GNP1).	Nitrogen	193-201	proline permease PUT4	Saccharomyces cerevisiae S288C	223-227
14968425-1	2004	We have found that proline and the toxic proline analogue azetidine-2-carboxylate (AzC) are efficiently imported into Saccharomyces cerevisiae cells by four amino acid permeases, including two nitrogen-regulated permeases (PUT4 and GAP1) and two permeases that are regulated by the SPS sensor of extracellular amino acids (AGP1 and GNP1).	Nitrogen	193-201	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	323-327
15059490-15	2004	FDP could also reduce neuronal degeneration and necrosis in hippocampal region CA(1) (the percentages of neuronal degeneration and necrosis in the 3 groups were respectively 13% for FD group, 28% for FS group and 30% for NS group).	Nitrogen	221-223	fructose-bisphosphatase 1	Rattus norvegicus	0-3
15059490-16	2004	There was a significant difference between FD group and the other two groups (P &lt; 0.05), FDP treatment could prevent interspace of neuronal synapses from enlarging (the mean interspace was 6.47 +/- 0.37 micro m for FD group, 7.60 +/- 0.36 micro m for FS group and 7.53 +/- 0.40 micro m for NS group.	Nitrogen	293-295	fructose-bisphosphatase 1	Rattus norvegicus	92-95
14697254-6	2004	These results suggest Agp2p and Agp3p function in amino acid transport when nitrogen sources are limiting and/or other permeases are inactive.	Nitrogen	76-84	Agp3p	Saccharomyces cerevisiae S288C	32-37
14715137-0	2004	N-glycosylation is essential for vesicular targeting of synaptotagmin 1.	Nitrogen	0-1	synaptotagmin 1	Homo sapiens	56-71
14715137-3	2004	Conversely, mutation of the N-terminal N-glycosylation site of synaptotagmin 1 redirects synaptotagmin 1 from vesicles to the plasma membrane.	Nitrogen	28-29	synaptotagmin 1	Homo sapiens	63-78
14715137-3	2004	Conversely, mutation of the N-terminal N-glycosylation site of synaptotagmin 1 redirects synaptotagmin 1 from vesicles to the plasma membrane.	Nitrogen	28-29	synaptotagmin 1	Homo sapiens	89-104
14715137-6	2004	Our data suggest that the intravesicular N-glycosylation site of synaptotagmin 1 collaborates with its cytoplasmic C(2) domains in directing synaptotagmin 1 to synaptic vesicles via a novel N-glycosylation-dependent mechanism.	Nitrogen	41-42	synaptotagmin 1	Homo sapiens	65-80
14715137-6	2004	Our data suggest that the intravesicular N-glycosylation site of synaptotagmin 1 collaborates with its cytoplasmic C(2) domains in directing synaptotagmin 1 to synaptic vesicles via a novel N-glycosylation-dependent mechanism.	Nitrogen	41-42	synaptotagmin 1	Homo sapiens	141-156
14715137-6	2004	Our data suggest that the intravesicular N-glycosylation site of synaptotagmin 1 collaborates with its cytoplasmic C(2) domains in directing synaptotagmin 1 to synaptic vesicles via a novel N-glycosylation-dependent mechanism.	Nitrogen	190-191	synaptotagmin 1	Homo sapiens	65-80
14715137-6	2004	Our data suggest that the intravesicular N-glycosylation site of synaptotagmin 1 collaborates with its cytoplasmic C(2) domains in directing synaptotagmin 1 to synaptic vesicles via a novel N-glycosylation-dependent mechanism.	Nitrogen	190-191	synaptotagmin 1	Homo sapiens	141-156
14753746-5	2004	MATERIALS AND METHODS: We examined the effect of the most potent nitrogen-containing BP available, zoledronic acid (ZOL), on the expression of RANKL and osteoprotegerin (OPG), critical factors in the regulation of OC formation and activation, in primary osteoblast (OB)-like cells derived from human bone, using flow cytometry, ELISA, semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR), in situ immunofluorescence staining, and Western blotting.	Nitrogen	65-73	TNF receptor superfamily member 11b	Homo sapiens	153-168
14753746-5	2004	MATERIALS AND METHODS: We examined the effect of the most potent nitrogen-containing BP available, zoledronic acid (ZOL), on the expression of RANKL and osteoprotegerin (OPG), critical factors in the regulation of OC formation and activation, in primary osteoblast (OB)-like cells derived from human bone, using flow cytometry, ELISA, semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR), in situ immunofluorescence staining, and Western blotting.	Nitrogen	65-73	TNF receptor superfamily member 11b	Homo sapiens	170-173
16233652-3	2004	The UGA1 disruptant derived from sake yeast could not grow on a medium with GABA as the sole nitrogen source.	Nitrogen	93-101	4-aminobutyrate transaminase	Saccharomyces cerevisiae S288C	4-8
33536743-1	2021	Background: Cyclophosphamide (CP) is an anticancer alkylating group (nitrogen mustard) and a prodrug that will be metabolized to form its active metabolite, 4-hydroxycyclophosphamide (4-OHCP).	Nitrogen	69-77	ceruloplasmin	Homo sapiens	30-32
14680402-4	2004	Whereas double-strand breaks in photon-irradiated cells were randomly distributed, irradiation of intact K562 cells with high-LET nitrogen ions produced an excess of non-randomly distributed DNA fragments 10 kb-1 Mbp in size.	Nitrogen	130-138	myelin basic protein	Homo sapiens	213-216
33427524-3	2021	Nitric oxide, which is produced by endothelial nitric oxide synthase (NOS3) or via the hemoglobin-medicated conversion of nitrite, interacts with ROS and results in the production of reactive nitrogen oxide species.	Nitrogen	192-200	nitric oxide synthase 3, endothelial cell	Mus musculus	35-68
33427524-3	2021	Nitric oxide, which is produced by endothelial nitric oxide synthase (NOS3) or via the hemoglobin-medicated conversion of nitrite, interacts with ROS and results in the production of reactive nitrogen oxide species.	Nitrogen	192-200	nitric oxide synthase 3, endothelial cell	Mus musculus	70-74
33157174-3	2021	N-Methyl-d-aspartate receptors (NMDARs) are abundant in the prefrontal cortex (PFc) and much evidence indicates that GluN2B-containing NMDARs are involved in morphine-induced conditioned place preference (CPP).	Nitrogen	0-1	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	117-123
33419227-0	2021	N-Glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function.	Nitrogen	0-1	serpin family C member 1	Homo sapiens	35-47
33419227-3	2021	Antithrombin, a serpin with four potential N-glycosylation sites, plays a pivotal role in hemostasis, wherein its deficiency significantly increases thrombotic risk.	Nitrogen	43-44	serpin family C member 1	Homo sapiens	0-12
32267154-8	2021	Alternate means of cleaving the same N-Calpha bond produce deprotonated cis-1,4-dibut-2-enoic acid z1 anion structures.	Nitrogen	37-38	cytokine inducible SH2 containing protein	Homo sapiens	72-77
32930709-4	2021	We also demonstrate that Jagn1 deficiency in B cells results in aberrant IgG N-glycosylation leading to enhanced Fc receptor binding.	Nitrogen	77-78	Fc receptor	Mus musculus	113-124
32857180-1	2021	nov., a nitrogen-fixing bacterial strain isolated from a native leguminous tree from the Amazon adapted to flooded conditions.	Nitrogen	8-16	cellular communication network factor 3	Homo sapiens	0-4
33256396-0	2020	Gas-Phase Peptide Fragmentation Induced by Hydrogen Attachment, from Principle to Sequencing of Amide Nitrogen-Methylated Peptides.	Nitrogen	102-110	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	0-3
33273096-5	2020	miR-223 restricts the EHT of lymphoid-myeloid lineages by suppressing the mannosyltransferase alg2 and sialyltransferase st3gal2, two enzymes involved in protein N-glycosylation.	Nitrogen	162-163	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	Homo sapiens	121-128
33335604-10	2020	Clearly, N-containing substituents such as NMe2 possess more electron-donating ability than the S-based moieties such as SMe.	Nitrogen	9-10	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	43-47
32767013-5	2020	The co-administration of Vit E and CLO significantly ameliorated CP-induced elevations in serum creatinine (Cr), blood urea nitrogen (BUN), interleukin 1 beta (IL-1beta), and interleukin- 6 (IL-6).	Nitrogen	124-132	vitrin	Rattus norvegicus	25-28
32966754-4	2020	Application of nociceptin/orphanin FQ (N/OFQ), a 17-amino acid neuropeptide which is the endogenous ligand for NOP receptor, inhibits the high-voltage activated (HVA)component of the calcium current in a concentration-dependent manner with a half inhibitory concentration of 26 nM.	Nitrogen	39-40	prepronociceptin	Rattus norvegicus	15-25
32966754-4	2020	Application of nociceptin/orphanin FQ (N/OFQ), a 17-amino acid neuropeptide which is the endogenous ligand for NOP receptor, inhibits the high-voltage activated (HVA)component of the calcium current in a concentration-dependent manner with a half inhibitory concentration of 26 nM.	Nitrogen	39-40	prepronociceptin	Rattus norvegicus	26-37
33257855-4	2020	Metabolomics and gene expression profiling pointed towards activation of the hexosamine biosynthesis pathway (HBP), another nitrogen-related metabolic pathway, in both mouse and human KRAS/LKB1 co-mutant tumours.	Nitrogen	124-132	serine/threonine kinase 11	Homo sapiens	189-193
32980951-5	2020	Expression analysis of CLE1-CLE7 revealed that these genes respond to different environmental stimuli, such as nitrogen deprivation, nitrogen replenishment, cold, salt, dark, and sugar starvation, in a sophisticated manner.	Nitrogen	111-119	CLAVATA3/ESR-RELATED 7	Arabidopsis thaliana	28-32
32980951-5	2020	Expression analysis of CLE1-CLE7 revealed that these genes respond to different environmental stimuli, such as nitrogen deprivation, nitrogen replenishment, cold, salt, dark, and sugar starvation, in a sophisticated manner.	Nitrogen	133-141	CLAVATA3/ESR-RELATED 7	Arabidopsis thaliana	28-32
33261145-1	2020	CD63, a member of transmembrane-4-superfamily of tetraspanin proteins and a highly N-glycosylated type III lysosomal membrane protein, is known to regulate malignancy of various types of cancers such as melanoma and breast cancer and serves as a potential marker for cancer detection.	Nitrogen	83-84	CD63 molecule	Homo sapiens	0-4
33170611-0	2020	New Insights into Co-pyrolysis among Graphitic Carbon Nitride and Organic Compounds: Carbonaceous Gas Fragments Induced Synthesis of Ultrathin Mesoporous Nitrogen-Doped Carbon Nanosheets for Heterogeneous Catalysis.	Nitrogen	154-162	gastrin	Homo sapiens	98-101
32677645-2	2020	Here we demonstrate that metallopolymerization of kinetically inert Ru2 metallomonomers via labile Ag-N bonds provides access to a family of atomically precise single-crystalline Ru2-based coordination polymers with varied network topology and primary coordination sphere.	Nitrogen	102-103	doublecortin domain containing 2	Homo sapiens	68-71
32677645-2	2020	Here we demonstrate that metallopolymerization of kinetically inert Ru2 metallomonomers via labile Ag-N bonds provides access to a family of atomically precise single-crystalline Ru2-based coordination polymers with varied network topology and primary coordination sphere.	Nitrogen	102-103	doublecortin domain containing 2	Homo sapiens	179-182
33329669-0	2020	The Arabidopsis Transcription Factor CDF3 Is Involved in Nitrogen Responses and Improves Nitrogen Use Efficiency in Tomato.	Nitrogen	57-65	cycling DOF factor 3	Arabidopsis thaliana	37-41
33329669-0	2020	The Arabidopsis Transcription Factor CDF3 Is Involved in Nitrogen Responses and Improves Nitrogen Use Efficiency in Tomato.	Nitrogen	89-97	cycling DOF factor 3	Arabidopsis thaliana	37-41
33329669-3	2020	Moreover, knockout cdf3 mutant plants exhibit nitrate-dependent lateral and primary root modifications, whereas CDF3 overexpression plants show increased biomass and enhanced root development under both nitrogen poor and rich conditions.	Nitrogen	203-211	cycling DOF factor 3	Arabidopsis thaliana	112-116
33329669-4	2020	Expression analyses of 35S::CDF3 lines reveled that CDF3 regulates the expression of an important set of nitrate responsive genes including, glutamine synthetase-1, glutamate synthase-2, nitrate reductase-1, and nitrate transporters NRT2.1, NRT2.4, and NRT2.5 as well as carbon assimilation genes like PK1 and PEPC1 in response to N availability.	Nitrogen	233-234	cycling DOF factor 3	Arabidopsis thaliana	52-56
33329669-5	2020	Consistently, metabolite profiling disclosed that the total amount of key N metabolites like glutamate, glutamine, and asparagine were higher in CDF3-overexpressing plants, but lower in cdf3-1 in N limiting conditions.	Nitrogen	74-75	cycling DOF factor 3	Arabidopsis thaliana	145-149
33329669-6	2020	Moreover, overexpression of CDF3 in tomato increased N accumulation and yield efficiency under both optimum and limiting N supply.	Nitrogen	53-54	cycling DOF factor 3	Arabidopsis thaliana	28-32
33329669-6	2020	Moreover, overexpression of CDF3 in tomato increased N accumulation and yield efficiency under both optimum and limiting N supply.	Nitrogen	121-122	cycling DOF factor 3	Arabidopsis thaliana	28-32
33329669-7	2020	These results highlight CDF3 as an important regulatory factor for the nitrate response, and its potential for improving N use efficiency in crops.	Nitrogen	121-122	cycling DOF factor 3	Arabidopsis thaliana	24-28
32889745-2	2020	The lone pair on the N atom of HCN is a better electron donor in the aerogen bond than the pi electron on the C=C bond of C 2 H 4 .	Nitrogen	21-22	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	31-34
33045830-9	2020	However, polymer 4 has a larger void volume and higher gas absorption ability for N2 gas than polymer 3.	Nitrogen	82-84	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	55-58
33045830-9	2020	However, polymer 4 has a larger void volume and higher gas absorption ability for N2 gas than polymer 3.	Nitrogen	82-84	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	85-88
33933135-9	2021	Serum asprosin was found to be positively related with disease duration, systolic blood pressure, blood urea nitrogen, creatinine, uric acid, ACR, calcium channel blockers, and angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker therapy, but negatively related with glomerular filtration rate, metformin, and acarbose therapy.	Nitrogen	109-117	fibrillin 1	Homo sapiens	6-14
33550059-0	2021	Faunal and environmental drivers of carbon and nitrogen cycling along a permeability gradient in shallow North Sea sediments.	Nitrogen	47-55	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	111-114
33859186-7	2021	These findings indicated that S-nitrosylation at Cys351 of PFKM by NOS1 contributes to the metabolic reprogramming of ovarian cancer cells, highlighting a critical role of endogenous nitrogen oxide on metabolism regulations in tumor progression.	Nitrogen	183-191	phosphofructokinase, muscle	Mus musculus	59-63
33852064-1	2021	OBJECTIVE: To assess the effects of epidermal growth factor (EGF)-coated titanium (Ti) discs on the adhesion and metabolism of keratinocytes and gingival fibroblasts exposed to nitrogen-containing bisphosphonates.	Nitrogen	177-185	epidermal growth factor	Homo sapiens	36-59
33733754-6	2021	Its microscopic origin is the unusual linear coordination of the Co(I) ions in Li2(Li1-xCox)N with two nitrogen ligands.	Nitrogen	103-111	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	65-70
33422879-0	2021	A flow injection fluorescence "turn-on" sensor for the determination of metformin hydrochloride based on the inner filter effect of nitrogen-doped carbon dots/gold nanoparticles double-probe.	Nitrogen	132-140	SAFB like transcription modulator	Homo sapiens	72-95
33422879-1	2021	In this paper, an ultrasensitive and rapid "turn-on" fluorescence sensor, integrating flow-injection (FI) with nitrogen-doped carbon dots/gold nanoparticles (N-CDs/AuNPs) double-probe is established for the determination of metformin hydrochloride (MET) in biological fluids.	Nitrogen	111-119	SAFB like transcription modulator	Homo sapiens	224-247
33422879-1	2021	In this paper, an ultrasensitive and rapid "turn-on" fluorescence sensor, integrating flow-injection (FI) with nitrogen-doped carbon dots/gold nanoparticles (N-CDs/AuNPs) double-probe is established for the determination of metformin hydrochloride (MET) in biological fluids.	Nitrogen	111-119	SAFB like transcription modulator	Homo sapiens	249-252
33648834-2	2021	Sodium 4-phenylbutyrate (NaPB), a standard therapy for UCDs for over 20 years, generates an alternative pathway of nitrogen deposition through glutamine consumption.	Nitrogen	115-123	NSF attachment protein beta	Homo sapiens	25-29
33476139-5	2021	High selectivity for N2O recovery was observed during beta-HQ clathrate formation from N2O/N2 gas mixtures with N2O concentrations exceeding 20%, whereas alpha-HQ traps only N2 molecules from gas mixtures.	Nitrogen	21-23	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	94-97
33476139-5	2021	High selectivity for N2O recovery was observed during beta-HQ clathrate formation from N2O/N2 gas mixtures with N2O concentrations exceeding 20%, whereas alpha-HQ traps only N2 molecules from gas mixtures.	Nitrogen	21-23	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	192-195
33309857-0	2021	Galactosyltransferase B4GALT1 confers chemoresistance in pancreatic ductal adenocarcinomas by upregulating N-linked glycosylation of CDK11p110.	Nitrogen	107-108	cyclin dependent kinase 11B	Homo sapiens	133-142
33309857-6	2021	Mechanistically, we show that elevated p65 activity transcriptionally up-regulates B4GALT1 expression, which then interacts with and stabilizes cyclin dependent kinase 11 isomer CDK11p110 protein via N-linked glycosylation, in order to promote cancer progression and chemoresistance.	Nitrogen	200-201	beta-1,4-galactosyltransferase 1	Homo sapiens	83-90
33309857-6	2021	Mechanistically, we show that elevated p65 activity transcriptionally up-regulates B4GALT1 expression, which then interacts with and stabilizes cyclin dependent kinase 11 isomer CDK11p110 protein via N-linked glycosylation, in order to promote cancer progression and chemoresistance.	Nitrogen	200-201	cyclin dependent kinase 11B	Homo sapiens	178-187
33595325-7	2021	Significantly, each CdSnSX2 form (X = Cl or Br) shows high visible-light-induced photocatalytic activity for rhodamine B degradation, which is ~7.0 times higher than that of nitrogen-doped TiO2 (TiO2-xNx) under the same experimental conditions.	Nitrogen	174-182	chromosome 12 open reading frame 73	Homo sapiens	44-46
33360738-3	2021	The comparative evaluation of our data indicated that (eta5-Cp*)Rh(III) cation is able to induce the deprotonation of amide nitrogen well below pH 7.	Nitrogen	124-132	ceruloplasmin	Homo sapiens	60-63
33126228-4	2021	Considering that the drawbacks of MRI contrast agent toxicity are still poorly addressed, we develop novel Mn2+ or Gd3+ doped nitrogen-containing graphene quantum dots (NGQDs) to equip NGQDs with MRI capabilities and at the same time render contrast agents biocompatible.	Nitrogen	126-134	GRDX	Homo sapiens	115-118
33586730-3	2021	In addition, the introduction of the CdS nanowire interlayer is more conducive to the extraction and transmission of electrons, which is attributed to a more suitable energy level alignment between the rear contact and the n-Si absorption layer.	Nitrogen	1-2	CDP-diacylglycerol synthase 1	Homo sapiens	37-40
33561155-11	2021	The highly intensified receptor interaction of BPC is attributable to the presence of an n-pi-pi-n conjugation system mediated through the >C = CCl2 double bond.	Nitrogen	12-13	C-C motif chemokine ligand 2	Homo sapiens	144-148
33561155-11	2021	The highly intensified receptor interaction of BPC is attributable to the presence of an n-pi-pi-n conjugation system mediated through the >C = CCl2 double bond.	Nitrogen	15-16	C-C motif chemokine ligand 2	Homo sapiens	144-148
33288345-0	2021	Separation based characterization methods for the N-glycosylation analysis of prostate-specific antigen.	Nitrogen	50-51	kallikrein related peptidase 3	Homo sapiens	78-103
33288345-5	2021	However, development of suitable methods and instrumentations to investigate the N-glycosylation profile of PSA represents a challenge.	Nitrogen	81-82	kallikrein related peptidase 3	Homo sapiens	108-111
33623851-3	2021	The molecular structures of Co3 and Co4 were determined by single-crystal X-ray diffraction, revealing the distorted-square-pyramidal geometry with three nitrogen atoms and two chlorine atoms around the cobalt center.	Nitrogen	154-162	complement C4A (Rodgers blood group)	Homo sapiens	36-39
33634989-0	2021	Vitamin D3 ameliorates nitrogen mustard-induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3-SOD2-mtROS signaling pathway.	Nitrogen	23-31	NLR family, pyrin domain containing 3	Mus musculus	91-96
33502255-3	2021	Materials & methods: Molecular dynamics tools were utilized to simulate the influence of CNTs doped with phosphorus, nitrogen and bromine and nitrogen on the formation of alpha-synuclein amyloid.	Nitrogen	117-125	synuclein alpha	Homo sapiens	171-186
33502255-3	2021	Materials & methods: Molecular dynamics tools were utilized to simulate the influence of CNTs doped with phosphorus, nitrogen and bromine and nitrogen on the formation of alpha-synuclein amyloid.	Nitrogen	142-150	synuclein alpha	Homo sapiens	171-186
33584765-9	2020	Among these enzymes, isocitrate dehydrogenase (ICDH) shows to be a good candidate to increase nitrogen assimilation in plants.	Nitrogen	94-102	isocitrate dehydrogenase	Arabidopsis thaliana	21-45
33584765-9	2020	Among these enzymes, isocitrate dehydrogenase (ICDH) shows to be a good candidate to increase nitrogen assimilation in plants.	Nitrogen	94-102	isocitrate dehydrogenase	Arabidopsis thaliana	47-51
33503066-7	2021	Furthermore, neither of these factors were affected with respect to sex, body mass index and several clinical parameters that were collected, except that a positive correlation was observed for Log V-FABP4 with blood urea nitrogen.	Nitrogen	222-230	fatty acid binding protein 4	Homo sapiens	200-205
33403379-4	2021	In this article, we have investigated the detailed mechanism and kinetics of the H2O catalyzed nitrogen reduction reaction (NRR) over bare and TiO2 doped Ru5 clusters in conjunction with DFT and TST calculations.	Nitrogen	95-103	thiosulfate sulfurtransferase	Homo sapiens	195-198
32916571-3	2021	The resulting material, APOP, possesses good thermal stability and a decent BET surface area, as exemplified by thermogravimetric analysis measurement and nitrogen gas sorption experiment.	Nitrogen	155-163	cytochrome c oxidase assembly factor 8	Homo sapiens	24-28
33523898-5	2021	Protein levels of the SSR3 subunit are ER stress and UBE2J1 dependent, revealing a mechanism that coordinates upstream N-glycosylation proficiency with downstream ER-associated degradation and proteostasis.	Nitrogen	119-120	ubiquitin conjugating enzyme E2 J1	Homo sapiens	53-59
33360414-1	2021	nov, a nitrogen-fixing and heavy oil degrading bacterium isolated from an oil production mixture of Yumen Oilfield.	Nitrogen	7-15	cellular communication network factor 3	Homo sapiens	0-3
34060360-0	2021	Removal of N-Linked Glycosylation Enhances PD-L1 Detection in Colon Cancer: Validation Research Based on Immunohistochemistry Analysis.	Nitrogen	11-12	CD274 molecule	Homo sapiens	43-48
34060360-3	2021	Recent research has revealed that the removal of N-Linked glycosylation significantly enhanced PD-L1 detection, resulting in both more accurate PD-L1 quantification and clinical outcome prediction.	Nitrogen	49-50	CD274 molecule	Homo sapiens	95-100
34060360-3	2021	Recent research has revealed that the removal of N-Linked glycosylation significantly enhanced PD-L1 detection, resulting in both more accurate PD-L1 quantification and clinical outcome prediction.	Nitrogen	49-50	CD274 molecule	Homo sapiens	144-149
34060360-7	2021	Most importantly, the results of the present study indicated that the removal of N-linked glycosylation remarkably enhanced PD-L1 detection.	Nitrogen	81-82	CD274 molecule	Homo sapiens	124-129
33374805-1	2020	N-glycosylation is instrumental to the regulation of CD147 functions, including the maturation of CD147, secretion of matrix metalloproteinases (MMPs), and promotion of tumor metastasis.	Nitrogen	0-1	basigin (Ok blood group)	Homo sapiens	53-58
33374805-1	2020	N-glycosylation is instrumental to the regulation of CD147 functions, including the maturation of CD147, secretion of matrix metalloproteinases (MMPs), and promotion of tumor metastasis.	Nitrogen	0-1	basigin (Ok blood group)	Homo sapiens	98-103
33374805-9	2020	Finally, the structures of the other potential CD147 N-glycosylation inhibitors may eventually provide guidance for future optimization.	Nitrogen	53-54	basigin (Ok blood group)	Homo sapiens	47-52
32926543-6	2020	In this work, we present the PNOCRA process (Plasma Nitrogen Oxidation and Catalytic Reduction to Ammonia), combining plasma-assisted nitrogen oxidation and Lean NOx Trap technology, adopted from diesel engine exhaust gas aftertreatment technology.	Nitrogen	52-60	gastrin	Homo sapiens	218-221
32926543-6	2020	In this work, we present the PNOCRA process (Plasma Nitrogen Oxidation and Catalytic Reduction to Ammonia), combining plasma-assisted nitrogen oxidation and Lean NOx Trap technology, adopted from diesel engine exhaust gas aftertreatment technology.	Nitrogen	134-142	gastrin	Homo sapiens	218-221
33152427-13	2021	RESULTS: Combination therapy (HKC plus MET) significantly improved the weight, reduced blood glucose (BG), blood urea nitrogen (BUN), total cholesterol (T-CHO), triglycerides (TG), low-density lipoprotein (LDL) and increased the level of high-density lipoprotein (HDL) of DN rats.	Nitrogen	118-126	SAFB like transcription modulator	Homo sapiens	39-42
32959924-4	2020	These results are complemented by the observation that N-glycosylation of GLMP in general, but not the type of N-glycans (high-mannose-type or complex-type) or individual N-glycan chains, are essential for protection.	Nitrogen	55-56	glycosylated lysosomal membrane protein	Homo sapiens	74-78
32681751-1	2020	ALG13 encodes a non-redundant, highly conserved, X-linked UDP-N-Acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation.	Nitrogen	62-63	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13	Saccharomyces cerevisiae S288C	0-5
32971423-3	2020	In the present study, two maize inbred lines (Ye478 and Wu312) were used to study the possible involvement of the auxin and target of rapamycin (TOR) pathway in low-N-induced root elongation.	Nitrogen	165-166	Serine/threonine-protein kinase TOR	Zea mays	145-148
32971423-7	2020	Furthermore, exogenous application of TOR inhibitor also eliminated the response of root elongation under low N.	Nitrogen	110-111	Serine/threonine-protein kinase TOR	Zea mays	38-41
32971423-9	2020	Taken together, it is concluded that low-N stress increases shoot-to-root auxin transport which enhances root elongation via auxin-dependent acid growth and the auxin-regulated TOR pathway in maize.	Nitrogen	41-42	Serine/threonine-protein kinase TOR	Zea mays	177-180
33105946-17	2020	The urea nitrogen levels of patients in PiCCO monitoring rehydration group on PID 1, 2, and 3 were (6.8+-1.5), (5.6+-1.4), (4.4+-1.4) mmol/L respectively, which were significantly lower than (8.6+-1.8), (6.6+-1.5), (5.5+-1.4) mmol/L in traditional rehydration group (t=3.817, 2.511, 2.903, P<0.05 or P<0.01).	Nitrogen	9-17	phosphotyrosine interaction domain containing 1	Homo sapiens	78-93
32975449-0	2020	Retraction of: Reactive Nitrogen Species Induced by Hyperglycemia Suppresses Akt Signaling and Triggers Apoptosis by Upregulating Phosphatase PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) in an LKB1-Dependent Manner.	Nitrogen	24-32	phosphatase and tensin homolog	Homo sapiens	142-146
32975449-0	2020	Retraction of: Reactive Nitrogen Species Induced by Hyperglycemia Suppresses Akt Signaling and Triggers Apoptosis by Upregulating Phosphatase PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) in an LKB1-Dependent Manner.	Nitrogen	24-32	serine/threonine kinase 11	Homo sapiens	213-217
33381229-1	2020	The Transient Receptor Potential Melastatin 4 (TRPM4) is a transmembrane N-glycosylated ion channel that belongs to the large family of TRP proteins.	Nitrogen	73-74	transient receptor potential cation channel subfamily M member 4	Homo sapiens	4-45
33381229-1	2020	The Transient Receptor Potential Melastatin 4 (TRPM4) is a transmembrane N-glycosylated ion channel that belongs to the large family of TRP proteins.	Nitrogen	73-74	transient receptor potential cation channel subfamily M member 4	Homo sapiens	47-52
32881503-2	2020	The prodrug moiety is attached to a benzimidazole nitrogen via an oxymethyl linkage to allow for rapid and complete release of the drug for absorption following phosphate removal by intestinal alkaline phosphatase.	Nitrogen	50-58	alkaline phosphatase, intestinal	Mus musculus	182-213
14644417-5	2003	Furthermore, chemical inhibition of N- and O-linked glycosylation interfered with the processing of the precursor and reduced the levels of dystroglycan at the cell surface.	Nitrogen	36-37	dystroglycan 1	Homo sapiens	140-152
33320095-6	2020	This study sheds light on differential specificities and roles of UGGT1 and UGGT2 and provides insight into the cellular reliance on carbohydrate-dependent chaperone system to facilitate proper folding and maturation of the cellular N-glycoproteome.	Nitrogen	233-234	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	66-71
14602417-1	2003	N-acylation of chitosan with various fatty acid (C(6)-C(16)) chlorides increased its hydrophobic character and made important changes in its structural features.	Nitrogen	0-1	complement C6	Homo sapiens	49-53
33320246-1	2021	The ST6GAL1 sialyltransferase, which adds alpha2-6 linked sialic acids to N-glycosylated proteins, is overexpressed in a wide range of human malignancies.	Nitrogen	74-75	immunoglobulin kappa variable 6-21 (non-functional)	Homo sapiens	42-50
33376455-7	2020	Understanding how different forms of N mediate the balance between primary production and decomposition is essential for managing coastal wetlands as N enrichment and sea level rise continue to assail our coasts.	Nitrogen	37-38	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	167-170
12867358-0	2003	Mutagenesis of the N-glycosylation site of hNaSi-1 reduces transport activity.	Nitrogen	19-20	solute carrier family 13 member 1	Homo sapiens	43-50
33201982-0	2020	The C2 domain of the ubiquitin ligase Rsp5 is required for ubiquitination of the endocytic protein Rvs167 upon change of nitrogen source.	Nitrogen	121-129	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	38-42
12867358-2	2003	In this study, the location and functional role of the N-glycosylation site of hNaSi-1 were studied using antifusion protein antibodies.	Nitrogen	55-56	solute carrier family 13 member 1	Homo sapiens	79-86
32972253-4	2020	Docking studies suggested that the formation of a salt bridge between the nitrogen of the aniline moiety with ASP678 of the Mer kinase domain as well as an interaction with the hinge region that most kinase inhibitors have in common would be essential to retain activity.	Nitrogen	74-82	MER proto-oncogene, tyrosine kinase	Homo sapiens	124-127
12827295-8	2003	Using a series of polyamine analogues, it was found that the most potent inducers of PAOh1/SMO possessed multiple three-carbon linkers between nitrogens, as typified by N1,N11-bis(ethyl)norspermine.	Nitrogen	143-152	spermine oxidase	Homo sapiens	85-90
32880978-0	2020	The role of CLV1, CLV2 and HPAT homologs in the nitrogen-regulation of root development.	Nitrogen	48-56	leucine rich repeat receptor like protein CLAVATA2	Solanum lycopersicum	18-22
32880978-3	2020	Recently, specific CLE peptides and/or receptors important for their perception, including CLV1 and CLV2, have been found to play roles in root development, including in response to N supply.	Nitrogen	182-183	leucine rich repeat receptor like protein CLAVATA2	Solanum lycopersicum	100-104
14504928-6	2003	By epitope-tagging, we further demonstrated that hCNT3 is N-glycosylated as PNGase F and Endo H deglycosylated hCNT3 from 67 kDa to 58 kDa.	Nitrogen	51-52	solute carrier family 28 member 3	Homo sapiens	111-116
33339804-3	2020	The pore volume and BET surface of ACCs were determined by nitrogen adsorption isotherms and scanning electron microscopy was used to observe their surface morphologies.	Nitrogen	59-67	1-aminocyclopropane-1-carboxylate synthase homolog (inactive)	Homo sapiens	35-39
33256741-7	2020	CONCLUSION: The prepared Mn-N-CNSs@Anti-HE4 with excellent biocompatibility, high-performance and superior tumor-targeting ability provides a novel fluorescence/MR dual-modal nanoprobe for specific labeling and detection of ovarian carcinoma cells in vitro and in vivo.	Nitrogen	2-3	WAP four-disulfide core domain 2	Homo sapiens	40-43
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	85-89
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	ubiquitin-binding serine/threonine protein kinase VPS15	Saccharomyces cerevisiae S288C	107-112
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	beclin 1	Saccharomyces cerevisiae S288C	210-214
33187417-3	2020	In this work, we demonstrate the capability of tip-enhanced Raman spectroscopy (TERS) to investigate the degree and spatial variability of the appearance of disorder in graphitic nanomaterials on the nanoscale with three different levels of nitrogen functionalization.	Nitrogen	241-249	TOR signaling pathway regulator	Homo sapiens	47-50
12826015-0	2003	N-linked glycosylation of native and recombinant cauliflower xyloglucan endotransglycosylase 16A.	Nitrogen	0-1	xyloglucan endotransglucosylase/hydrolase	Brassica oleracea	61-92
33223841-5	2020	Importantly, the serum level of asprosin was positively correlated with UACR (r=0.304, P<0.001), creatinine (r=0.157, P=0.024), blood urea nitrogen (BUN) (r=0.244, P<0.001), and negatively with glomerular filtration rate (eGFR) (r=-0.159, P=0.022).	Nitrogen	139-147	fibrillin 1	Homo sapiens	32-40
12847110-7	2003	Our results suggest that N inhibits angiogenesis not by disrupting the HGF/c-met interaction but rather by interfering with the endothelial glycosaminoglycans, which are the secondary binding sites of HGF.	Nitrogen	25-26	hepatocyte growth factor	Homo sapiens	71-74
33172169-6	2020	Our results open a new direction for the development of small-molecule ANO1 blockers composed of a pyrimidine scaffold and a nitrogen-containing heterocyclic moiety, with drug-like properties.	Nitrogen	125-133	anoctamin 1	Homo sapiens	71-75
12847110-7	2003	Our results suggest that N inhibits angiogenesis not by disrupting the HGF/c-met interaction but rather by interfering with the endothelial glycosaminoglycans, which are the secondary binding sites of HGF.	Nitrogen	25-26	hepatocyte growth factor	Homo sapiens	201-204
12932825-5	2003	ORL1 was abundantly expressed with a high degree of coexpression with SP (72%) and CGRP (82%) suggesting that N/OFQ may presynaptically modulate primary sensory nociceptive signaling.	Nitrogen	110-111	opioid related nociceptin receptor 1	Rattus norvegicus	0-4
33153486-9	2020	The association between PM10-2.5 and PAI-1 remained unchanged with adjustment for PM2.5, ozone, nitrogen dioxide, and carbon monoxide.	Nitrogen	96-104	serpin family E member 1	Homo sapiens	37-42
33167499-5	2020	Correlation of Bgl2 distribution among pools and its N-glycosylation was not found.	Nitrogen	53-54	glucan 1,3-beta-glucosidase	Saccharomyces cerevisiae S288C	15-19
12932825-5	2003	ORL1 was abundantly expressed with a high degree of coexpression with SP (72%) and CGRP (82%) suggesting that N/OFQ may presynaptically modulate primary sensory nociceptive signaling.	Nitrogen	110-111	calcitonin-related polypeptide alpha	Rattus norvegicus	83-87
32726584-6	2020	These results suggest that both Stt4p and Pik1p have important roles in the microautophagy of the vacuole in the stationary phase and under nitrogen starvation conditions.	Nitrogen	140-148	1-phosphatidylinositol 4-kinase STT4	Saccharomyces cerevisiae S288C	32-37
12911312-0	2003	Mass spectrometric identification of N- and O-glycosylation sites of full-length rat selenoprotein P and determination of selenide-sulfide and disulfide linkages in the shortest isoform.	Nitrogen	37-38	selenoprotein P	Rattus norvegicus	85-100
33275236-13	2020	In comparison with the model group, miR-34a inhibitor group had lowered serum creatinine level, urea nitrogen level, expressions of miR-34a, TNF-alpha and Bcl-2, and apoptotic rate (p<0.05), but raised levels of KLF4 and IL-10 (p<0.05), showing statistically significant differences.	Nitrogen	101-109	microRNA 34a	Rattus norvegicus	36-43
12902239-7	2003	Furthermore, the transcript level of one candidate gene (ARO10) increased 30-fold when phenylalanine replaced ammonia as the sole nitrogen source.	Nitrogen	130-138	phenylpyruvate decarboxylase ARO10	Saccharomyces cerevisiae S288C	57-62
32971423-0	2020	Low nitrogen induces root elongation via auxin-induced acid growth and auxin-regulated target of rapamycin (TOR) pathway in maize.	Nitrogen	4-12	Serine/threonine-protein kinase TOR	Zea mays	108-111
12885904-6	2003	We show that A14 is modified by N-linked glycosylation both in vitro and in vivo.	Nitrogen	32-33	immunoglobulin kappa variable 6D-41 (non-functional)	Homo sapiens	13-16
32280962-2	2020	PSG1 has seven potential N-linked glycosylation sites across its four domains.	Nitrogen	25-26	pregnancy specific beta-1-glycoprotein 1	Homo sapiens	0-4
32280962-6	2020	In addition, we determined that out of the three N-glycosylation-carrying domains, only the N and A2 domains of recombinant PSG1 interact with Gal-1.	Nitrogen	49-50	pregnancy specific beta-1-glycoprotein 1	Homo sapiens	124-128
12869648-2	2003	It has been hypothesized that the DAT transmembrane aspartic acid residue D79 forms an ionic interaction with charged nitrogen atoms in both dopamine and cocaine.	Nitrogen	118-126	solute carrier family 6 member 3	Rattus norvegicus	34-37
33043956-0	2020	Synthesis of alpha-aminooxy amides through [3 + 3] cycloaddition and Sc(OTf)3-catalyzed double C-N bond cleavage in a one-pot reaction.	Nitrogen	97-98	POU class 5 homeobox 1	Homo sapiens	69-77
33043956-3	2020	Mechanistic studies show that the reaction initially proceeds through [3 + 3] cycloaddition between N-vinyl nitrones and aza-oxyallyl cations generated from alpha-bromohydroxamates to afford six-membered N,O-heterocycles, followed by double C-N bond cleavage in the presence of the Sc(OTf)3 catalyst.	Nitrogen	100-101	POU class 5 homeobox 1	Homo sapiens	282-290
32996919-7	2020	The concentration of renal function-related molecules, creatinine and blood urea nitrogen diminished in the ECM scaffold with MH NPs.	Nitrogen	81-89	multimerin 1	Homo sapiens	108-111
12844133-9	2003	CONCLUSIONS: These results indicate that artemisinin induces the N-demethylation of S-mephenytoin probably by an increased capacity of CYP2B6.	Nitrogen	2-3	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	135-141
32755678-9	2020	A molecular docking study was executed to shed light on the supposed binding mode of the lead compound, STCY1, into the selective pocket of SIRT2 by interaction of the nitrogen of pyridine ring of the compound and Ala135 of the protein.	Nitrogen	168-176	sirtuin 2	Homo sapiens	140-145
33080215-4	2022	William B. Jakoby and associates were the first to report the biotransformation of organic nitrates, notably including nitroglycerin (i.e., glycerol trinitrate; GTN), by glutathione S-transferase (GST)-catalyzed conjugation of glutathione (GSH) to the nitrogen atom of one of the three nitrate groups of GTN to generate glutathione sulfenyl nitrite (glutathione thionitrate, S-nitroglutathione; GSNO2).	Nitrogen	252-260	glutathione S-transferase kappa 1	Homo sapiens	170-195
33080215-4	2022	William B. Jakoby and associates were the first to report the biotransformation of organic nitrates, notably including nitroglycerin (i.e., glycerol trinitrate; GTN), by glutathione S-transferase (GST)-catalyzed conjugation of glutathione (GSH) to the nitrogen atom of one of the three nitrate groups of GTN to generate glutathione sulfenyl nitrite (glutathione thionitrate, S-nitroglutathione; GSNO2).	Nitrogen	252-260	glutathione S-transferase kappa 1	Homo sapiens	197-200
32847853-8	2020	We found that EBV gH/gL-N69L/S71V had higher binding affinity for EphA2, indicating that the EBV gL N-glycosylation site might be responsible for inhibiting the binding of gH/gL to EphA2.	Nitrogen	24-25	gamma-glutamyl hydrolase	Homo sapiens	18-20
32847853-9	2020	Loss of N-glycosylation at this site may remove steric hindrance that reduces EBV gH/gL binding to EphA2.	Nitrogen	8-9	gamma-glutamyl hydrolase	Homo sapiens	82-84
32909571-2	2020	The as-synthesized Au GSD are bound by high-index {331} facets and exhibit excellent electrocatalytic performance for the nitrogen reduction reaction with a high NH3 yield rate (49.96 mug h-1 cm-2) and faradaic efficiency (28.59%) under ambient conditions.	Nitrogen	122-130	H1.5 linker histone, cluster member	Homo sapiens	188-196
32989163-4	2020	In contrast to FTO, which follows a traditional oxidative N-demethylation pathway to catalyze conversion of m6A to hm6A with subsequent slow release of A and FA, we find that ALKBH5 catalyzes a direct m6A-to-A transformation with rapid FA release.	Nitrogen	58-59	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	15-18
33003994-8	2020	It showed up-regulation of Exp (24), and Nrt (9) gene family members, which increased the nitrogen absorption and down-regulation of Pet (3), Psb (8), Nar (3), and Nir (1) gene family members hampered photosynthesis and nitrogen metabolism.	Nitrogen	220-228	ferredoxin--nitrite reductase, chloroplastic	Triticum aestivum	164-167
32871472-15	2020	These models of N-glycosylated and ubiquitinated PD-L1 will be useful to study other PD-L1 protein complexes.	Nitrogen	16-17	CD274 molecule	Homo sapiens	85-90
32030768-6	2020	The expression of PD-L1 in tumor cells was significantly associated with N stage (P = .024), chemotherapy (p = .032), and clinical stage (p = .019).	Nitrogen	73-74	CD274 molecule	Homo sapiens	18-23
12855738-6	2003	The gp119 AIDA-I cellular receptor protein was characterized biochemically and found to be an integral N-glycosylated membrane protein with a pI of 5.2.	Nitrogen	103-104	axin interactor, dorsalization associated	Homo sapiens	10-14
32246626-0	2020	The Janus face of N-terminal lysines in alpha-synuclein.	Nitrogen	18-19	synuclein alpha	Homo sapiens	40-55
32897698-3	2020	Herein, CoP nanoparticles coated with metal-organic framework derived N-doped mesoporous carbon (CoP@N-C) composites are synthesized and applied in both cathodes for sulfur host and modified layer on separators for high-energy-density Li-S batteries since the CoP component has strong chemical anchoring capability toward soluble polysulfides and high electrochemical activity toward polysulfides transformation.	Nitrogen	70-71	caspase recruitment domain family member 16	Homo sapiens	8-11
32897698-3	2020	Herein, CoP nanoparticles coated with metal-organic framework derived N-doped mesoporous carbon (CoP@N-C) composites are synthesized and applied in both cathodes for sulfur host and modified layer on separators for high-energy-density Li-S batteries since the CoP component has strong chemical anchoring capability toward soluble polysulfides and high electrochemical activity toward polysulfides transformation.	Nitrogen	70-71	caspase recruitment domain family member 16	Homo sapiens	97-100
32897698-3	2020	Herein, CoP nanoparticles coated with metal-organic framework derived N-doped mesoporous carbon (CoP@N-C) composites are synthesized and applied in both cathodes for sulfur host and modified layer on separators for high-energy-density Li-S batteries since the CoP component has strong chemical anchoring capability toward soluble polysulfides and high electrochemical activity toward polysulfides transformation.	Nitrogen	70-71	caspase recruitment domain family member 16	Homo sapiens	97-100
32924514-3	2020	Herein, we report the design and preparation of nitrogen-doped carbon dots functionalized with atomically dispersed copper centers by Cu-N coordination (Cu/NCD) that exhibit apparent antibacterial activity towards Gram-negative Escherichia coli (E. coli) under photoirradiation.	Nitrogen	48-56	protein K	Escherichia coli	134-138
33020580-1	2020	Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism.	Nitrogen	70-78	glutamate dehydrogenase 1	Homo sapiens	0-23
33020580-1	2020	Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism.	Nitrogen	70-78	glutamate dehydrogenase 1	Homo sapiens	25-28
12818695-2	2003	Although with a lower affinity than cytisine, new cytisine derivatives with different substituents on the basic nitrogen (CC1-CC8) bind to both the heteromeric and homomeric subtypes, with higher affinity for brain [3H]epibatidine receptors.	Nitrogen	112-120	Cardiac cell morphology QTL 1	Rattus norvegicus	122-129
32980111-0	2020	A self-enhanced ECL-RET immunosensor for the detection of CA19-9 antigen based on Ru(bpy)2(phen-NH2)2+ - Amine-rich nitrogen-doped carbon nanodots as probe and graphene oxide grafted hyperbranched aromatic polyamide as platform.	Nitrogen	116-124	ret proto-oncogene	Homo sapiens	20-23
33043217-4	2020	Zeolites NaK ZK-4 with Si/Al = 1.8 had high CO2 uptake capacity and very high CO2-over-N2 selectivity (1190).	Nitrogen	87-89	TANK binding kinase 1	Homo sapiens	9-12
31944172-11	2020	This study shows that sustained high autophagic flux by RUBCN deficiency in PTECs leads to metabolic syndrome concomitantly with an accelerated mobilization of phospholipids from cellular membranes to lysosomes.Abbreviations: ABC: ATP binding cassette; ACADM: acyl-CoA dehydrogenase medium chain; ACTB: actin, beta; ATG: autophagy related; AUC: area under the curve; Baf: bafilomycin A1; BAT: brown adipose tissue; BODIPY: boron-dipyrromethene; BSA: bovine serum albumin; BW: body weight; CAT: chloramphenicol acetyltransferase; CM: complete medium; CPT1A: carnitine palmitoyltransferase 1a, liver; CQ: chloroquine; CTRL: control; EGFP: enhanced green fluorescent protein; CTSD: cathepsin D; EAT: epididymal adipose tissue; EGFR: epidermal growth factor receptor; EIF4EBP1: eukaryotic translation initiation factor 4E binding protein 1; FA: fatty acid; FBS: fetal bovine serum; GTT: glucose tolerance test; HE: hematoxylin and eosin; HFD: high-fat diet; I/R: ischemia-reperfusion; ITT: insulin tolerance test; KAP: kidney androgen regulated protein; KO: knockout; LAMP1: lysosomal associated membrane protein 1; LD: lipid droplet; LRP2: low density lipoprotein receptor related protein 2; MAP1LC3B: microtubule associated protein 1 light chain 3 beta; MAT: mesenteric adipose tissue; MS: mass spectrometry; MTOR: mechanistic target of rapamycin kinase; MTORC1: MTOR complex 1; NDRG1: N-myc downstream regulated 1; NDUFB5: NADH:ubiquinone oxidoreductase subunit B5; NEFA: non-esterified fatty acid; OA: oleic acid; OCT: optimal cutting temperature; ORO: Oil Red O; PAS: Periodic-acid Schiff; PFA: paraformaldehyde; PIK3C3: phosphatidylinositol 3-kinase catalytic subunit type 3; PPARA: peroxisome proliferator activated receptor alpha; PPARGC1A: PPARG coactivator 1 alpha; PTEC: proximal tubular epithelial cell; RAB7A: RAB7A, member RAS oncogene family; RPS6: ribosomal protein S6; RPS6KB1: ribosomal protein S6 kinase B1; RT: reverse transcription; RUBCN: rubicon autophagy regulator; SAT: subcutaneous adipose tissue; SFC: supercritical fluid chromatography; SQSTM1: sequestosome 1; SREBF1: sterol regulatory element binding transcription factor 1; SV-40: simian virus-40; TFEB: transcription factor EB; TG: triglyceride; TS: tissue specific; TUNEL: terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling; UN: urea nitrogen; UQCRB: ubiquinol-cytochrome c reductase binding protein; UVRAG: UV radiation resistance associated; VPS: vacuolar protein sorting; WAT: white adipose tissue.	Nitrogen	2332-2340	RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein	Mus musculus	56-61
32615448-2	2020	Nitrogen mass balance revealed that 44.87% and 43.77% losses of T-N in CW1 and CW2 were unaccounted for.	Nitrogen	0-8	dynein light chain Tctex-type 1	Homo sapiens	71-74
32615448-2	2020	Nitrogen mass balance revealed that 44.87% and 43.77% losses of T-N in CW1 and CW2 were unaccounted for.	Nitrogen	0-1	dynein light chain Tctex-type 1	Homo sapiens	71-74
32615448-4	2020	The ratio of NH4+-N (removed) & NO3--N (produced) in CW1 & CW2 indicated that ANAMMOX could be one of the key pathways for nitrogen removal in the CWs besides nitrification-denitrification in microbial films.	Nitrogen	123-131	dynein light chain Tctex-type 1	Homo sapiens	53-56
32891857-0	2020	Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds - Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and alpha-glycosidase inhibition properties.	Nitrogen	13-21	butyrylcholinesterase	Homo sapiens	156-177
31916158-5	2020	The Eco-Exergy-based indices and Margalef index were significantly, negatively correlated with dissolved inorganic nitrogen and reactive phosphate, and significantly, positively correlated with the salinity of seawater.	Nitrogen	115-123	ciliogenesis associated kinase 1	Homo sapiens	4-7
32767150-8	2020	We found that N- and O-glycosylation patterns of CGB7 and CGB3/5/8 are quite similar.	Nitrogen	14-15	chorionic gonadotropin subunit beta 7	Homo sapiens	49-53
32897081-3	2020	In this work, by using spin-polarized density functional theory calculations, we systematically investigated electrochemical nitrogen reduction reaction (eNRR) performance catalyzed by Mox (x = 1-4) supported on graphdiyne (GDY).	Nitrogen	125-133	monooxygenase DBH like 1	Homo sapiens	185-188
32222383-7	2020	This study expands our knowledge of methanogenesis at high temperatures and the involvement of these microorganisms in the carbon and nitrogen cycles of deep-sea hydrothermal environments.	Nitrogen	134-142	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	158-161
32739631-0	2020	Nitrogen sources, processes, and associated impacts of climate and land-use changes in a coastal China watershed: Insights from the INCA-N model.	Nitrogen	0-8	caspase recruitment domain family member 17	Homo sapiens	132-136
32739631-0	2020	Nitrogen sources, processes, and associated impacts of climate and land-use changes in a coastal China watershed: Insights from the INCA-N model.	Nitrogen	0-1	caspase recruitment domain family member 17	Homo sapiens	132-136
32648010-0	2020	Characterization on TaMPK14, an MAPK family gene of wheat, in modulating N-starvation response through regulating N uptake and ROS homeostasis.	Nitrogen	73-74	mitogen-activated protein kinase 7-like	Nicotiana tabacum	32-36
33011678-1	2020	Peroxiredoxins (Prxs) are antioxidant proteins that are involved in cellular defence against reactive oxygen species and reactive nitrogen species.	Nitrogen	130-138	peroxiredoxin 1	Homo sapiens	0-14
32415968-6	2020	The extracellular portion of CLEC4A specifically binds to murine cDC cell line expressing CLEC4A, while its extracellular portion lacking the N-glycosylation site or the EPS motif within the CRD reduces their association.	Nitrogen	142-143	C-type lectin domain family 4, member a2	Mus musculus	29-35
32892942-8	2020	Moreover, in the LC-MS/MS analysis of real biological sample, a total of 344 unique N-glycosites in 598 unique N-glycopeptides from 172 N-glycoproteins were identified from 2 muL human serum after deglycosylated by PNGase F, and 825 intact N-glycopeptides with different types of glycoform were detected when directly analyzed the N-glycopeptides enriched by PAM-OH HMS.	Nitrogen	84-85	N-glycanase 1	Homo sapiens	215-221
32999831-3	2020	Herein, a free-standing Co3Fe7 nanoalloy and Co5.47N encapsulated in 3D nitrogen-doped carbon foam (Co3Fe7@Co5.47N/NCF) is prepared as an additive-free and integrated air cathode for flexible Al-air batteries in both alkaline and neutral electrolytes.	Nitrogen	72-80	neutrophil cytosolic factor 4	Homo sapiens	115-118
32692156-0	2020	The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway.	Nitrogen	68-69	activating transcription factor 3	Homo sapiens	4-8
32692156-8	2020	We also show, through chase-degradation assays with [UBR1-/- UBR2-/-] and wild-type human cells, that the Arg/N-degron pathway mediates a large fraction of ATF3 degradation.	Nitrogen	110-111	activating transcription factor 3	Homo sapiens	156-160
32692156-11	2020	These and other binding patterns, whose mechanics remain to be understood, may signify a conditional (regulated) degradation of ATF3 by the Arg/N-degron pathway.	Nitrogen	144-145	activating transcription factor 3	Homo sapiens	128-132
32310329-0	2020	Comprehensive N- and O-glycosylation Mapping of Human Coagulation Factor V.	Nitrogen	14-15	coagulation factor V	Homo sapiens	54-74
32608962-2	2020	However, the complex behavior of the p-kesterite/n-FTO back interface potentially limits the power conversion efficiency of such devices.	Nitrogen	49-50	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	51-54
32602701-4	2020	Abolishing N-linked glycosylation by tunicamycin, glucosamine supplementation, or glutamine substitutions of all four potential Asn glycosylation sites blocked myonectin secretion.	Nitrogen	11-12	erythroferrone	Homo sapiens	160-169
32793580-8	2020	Surprisingly glucose repression protein kinase Snf1 and Nitrogen Catabolite Repression transcription factor Gln3 are relevant in fermentation, even in the absence of starvation.	Nitrogen	56-64	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	108-112
32694126-4	2020	System performance was quantified as the ratio of the fed ammonium converted to anammox-derived nitrogen gas (N2) versus nitrification-derived nitrate (npNO3 -).	Nitrogen	96-104	gastrin	Homo sapiens	105-108
32073833-5	2020	15N isotopic labeling confirms the reduction state by measuring the NO stretching frequency (1392 cm-1 for kappaN-ArNO, 1226 cm-1 for eta2-ArNO -, 1133 cm-1 for dinuclear mu-eta2:eta1-ArNO -, and 875 cm-1 for dinuclear mu-eta2:eta2 for ArNO2-).	Nitrogen	0-3	secreted phosphoprotein 1	Homo sapiens	179-183
32635192-2	2020	Similarly, acute exposure to nitrogen mustard (NM) is related to the development of chronic lung injury driven by TNF-alpha, TGF-beta, ERK and HSP90.	Nitrogen	29-37	transforming growth factor alpha	Mus musculus	125-133
31898397-2	2020	Reactive oxygen and nitrogen species (ROS/RNS) are among the various factors affecting the host as well as the implant components.	Nitrogen	20-28	FAM20C golgi associated secretory pathway kinase	Homo sapiens	42-45
32542927-2	2020	Notably, its specific receptor, Nogo-B receptor (NgBR), encoded by NUS1, has been implicated in many crucial cellular processes, such as cholesterol trafficking, lipid metabolism, dolichol synthesis, protein N-glycosylation, vascular remodelling, angiogenesis, tumorigenesis and neurodevelopment.	Nitrogen	0-1	NUS1 dehydrodolichyl diphosphate synthase subunit	Homo sapiens	32-47
32542927-2	2020	Notably, its specific receptor, Nogo-B receptor (NgBR), encoded by NUS1, has been implicated in many crucial cellular processes, such as cholesterol trafficking, lipid metabolism, dolichol synthesis, protein N-glycosylation, vascular remodelling, angiogenesis, tumorigenesis and neurodevelopment.	Nitrogen	0-1	NUS1 dehydrodolichyl diphosphate synthase subunit	Homo sapiens	49-53
32542927-2	2020	Notably, its specific receptor, Nogo-B receptor (NgBR), encoded by NUS1, has been implicated in many crucial cellular processes, such as cholesterol trafficking, lipid metabolism, dolichol synthesis, protein N-glycosylation, vascular remodelling, angiogenesis, tumorigenesis and neurodevelopment.	Nitrogen	0-1	NUS1 dehydrodolichyl diphosphate synthase subunit	Homo sapiens	67-71
31891182-4	2020	In live transfected HEK293 cells, TPBG was localized to the plasma membrane with the N-terminal LRR domain facing the extracellular space.	Nitrogen	85-86	trophoblast glycoprotein	Homo sapiens	34-38
32077945-6	2020	Importantly, we reveal that DNMT3C is composed of two independently evolving segments: the latter two-thirds has undergone recurrent gene conversion with Dnmt3B, whereas the N-terminus has instead evolved under strong diversifying selection.	Nitrogen	29-30	DNA methyltransferase 3 beta	Homo sapiens	154-160
31822129-6	2020	The procedure was also successfully tried on hydrophilic tetra- and hexa-peptides of Ribonuclease B carrying an N-glycosylation site occupied with "high-mannose" N-glycan chains.	Nitrogen	112-113	hexosaminidase subunit alpha	Homo sapiens	68-72
32970058-0	2020	Tri-(Fe/F/N)-doped porous carbons as electrocatalysts for the oxygen reduction reaction in both alkaline and acidic media.	Nitrogen	10-11	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	0-3
32966780-2	2020	Here, we report that FAM46C selectively stabilizes mRNAs encoding endoplasmic reticulum (ER)-targeted proteins, thereby concertedly enhancing the expression of proteins that control ER protein import, folding, N-glycosylation, and trafficking and boosting protein secretion.	Nitrogen	53-54	terminal nucleotidyltransferase 5C	Homo sapiens	21-27
32962231-0	2020	Effects of Kifunensine on Production and N-Glycosylation Modification of Butyrylcholinesterase in a Transgenic Rice Cell Culture Bioreactor.	Nitrogen	41-42	butyrylcholinesterase	Homo sapiens	73-94
32961912-8	2020	Blood biochemical parameters showed that Broiler chickens fed on the SP2 diet had higher levels of total protein (TP) (p <= 0.05), albumin (ALB) (p <= 0.05), creatinine (CRE) (p <= 0.05), and aspartate aminotransferase (AST) (p <= 0.05) and, lower level of uric acid (UA) (p <= 0.05), blood urea nitrogen (BUN) (p <= 0.05), glucose (GLU) (p <= 0.05), and alanine aminotransferase (ALT) (p <= 0.05) in the starter phase; however, higher level of TP (p <= 0.05), GLU (p <= 0.05), CRE (p <= 0.05), and AST (p <= 0.05), and lower level of ALB (p <= 0.05), UA (p <= 0.05), and ALT (p <= 0.05) in the grower phase; RPGC had higher level of TP (p <= 0.05), UA (p <= 0.05), GLU (p <= 0.05), ALT (p <= 0.05) and AST (p <= 0.05), and lower level of ALB (p <= 0.05), BUN (p <= 0.05), and CRE (p <= 0.05) in the starter phase; however, in grower phase, RPGC had higher level of TP (p <= 0.05), and ALB (p <= 0.05), and lower level of UA (p <= 0.05), CRE (p <= 0.05), ALT (p <= 0.05), and AST (p <= 0.05).	Nitrogen	296-304	Sp2 transcription factor	Gallus gallus	69-72
12810672-7	2003	Binding of testican 2 to N-Tes deposited on collagen allowed migration of cells expressing MT1-MMP.	Nitrogen	25-26	matrix metallopeptidase 14	Homo sapiens	91-98
32474175-7	2020	The high n-3 PUFA diet increased the mRNA expression of EL, FABPpm, and Mfsd2a at both gestation days, compared to other groups.	Nitrogen	9-10	lipase, endothelial	Mus musculus	56-58
32474175-9	2020	The high n-3 PUFA diet also increased the mRNA expressions of BDNF, TrKB and CREB, as well as the protein concentration of pCREB as gestation progressed, compared to the other groups.	Nitrogen	9-10	brain derived neurotrophic factor	Mus musculus	62-66
32982674-7	2020	Surprisingly, we found that nNOS knockdown exhibited greatly reduced excitatory synaptic transmission concomitant with the lower surface expression of GluN2B-containing N-methyl-D-aspartate receptors and postsynaptic density protein 95 in mice.	Nitrogen	29-30	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	151-157
31960921-2	2020	HLTF, a SNF2 translocase, plays a central role in the fork regression and its N-terminal domain, HIRAN, binds the 3"-hydroxy group of ssDNA.	Nitrogen	9-10	helicase like transcription factor	Homo sapiens	0-4
32112948-4	2020	The hydrophobic surface of GAC could selectively adsorb hydrophobic protein and favor anammox bacteria attachment, which contributed to achieving a total nitrogen removal rate of 0.40 kg-N/(m3 d) in 60 days.	Nitrogen	154-162	glutaminase	Homo sapiens	27-30
12796300-2	2003	Among other effects, rapamycin treatment results in the nuclear localization of the global nitrogen activators Gln3p and Nil1p/Gat1p, which leads to expression of nitrogen assimilation genes.	Nitrogen	91-99	Gat1p	Saccharomyces cerevisiae S288C	121-126
32528505-6	2020	Based on the observation in the double mutants fugu5-1 ppa1 and fugu5-1 ppa4 of more severe atrophy compared to fugu5-1, the nitrogen-dependent phenotype might be linked to PPi metabolism.	Nitrogen	125-133	Inorganic H pyrophosphatase family protein	Arabidopsis thaliana	47-52
12796300-2	2003	Among other effects, rapamycin treatment results in the nuclear localization of the global nitrogen activators Gln3p and Nil1p/Gat1p, which leads to expression of nitrogen assimilation genes.	Nitrogen	91-99	Gat1p	Saccharomyces cerevisiae S288C	127-132
32799447-2	2020	Herein, a well-designed nanoarray-structured nitrogen-doped graphite foil (NNGF) substrate is introduced to support Pt SACs in Pt-N4 construction (Pt1/NNGF) for HER.	Nitrogen	45-53	zinc finger protein 77	Homo sapiens	147-150
12796300-2	2003	Among other effects, rapamycin treatment results in the nuclear localization of the global nitrogen activators Gln3p and Nil1p/Gat1p, which leads to expression of nitrogen assimilation genes.	Nitrogen	163-171	Gat1p	Saccharomyces cerevisiae S288C	121-126
12796300-2	2003	Among other effects, rapamycin treatment results in the nuclear localization of the global nitrogen activators Gln3p and Nil1p/Gat1p, which leads to expression of nitrogen assimilation genes.	Nitrogen	163-171	Gat1p	Saccharomyces cerevisiae S288C	127-132
12726995-0	2003	The role of N-linked glycosylation in determining the surface expression, G protein interaction and effector coupling of the alpha (alpha) isoform of the human thromboxane A(2) receptor.	Nitrogen	12-13	thromboxane A2 receptor	Homo sapiens	160-185
32579360-4	2020	To overcome this, we recently developed an effectorless TfRMAb-EPO fusion protein, designated TfRMAb-N292G-EPO, by eliminating the Fc N-linked glycosylation site at position 292 of the antibody heavy chain.	Nitrogen	101-102	erythropoietin	Mus musculus	56-66
32523604-0	2020	GTR1 Affects Nitrogen Consumption and TORC1 Activity in Saccharomyces cerevisiae Under Fermentation Conditions.	Nitrogen	13-21	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	0-4
32523604-4	2020	Previously, we demonstrated that allelic variants in the GTR1 gene underlying differences in ammonium and amino acids consumption between Wine/European (WE) and West African (WA) strains impact the expression of nitrogen transporters.	Nitrogen	212-220	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	57-61
32523604-6	2020	In this work, we assessed the role of the GTR1 gene on nitrogen consumption under fermentation conditions, using a high sugar concentration medium with nitrogen limitation and in the context of the WE and WA genetic backgrounds.	Nitrogen	55-63	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	42-46
32579360-4	2020	To overcome this, we recently developed an effectorless TfRMAb-EPO fusion protein, designated TfRMAb-N292G-EPO, by eliminating the Fc N-linked glycosylation site at position 292 of the antibody heavy chain.	Nitrogen	101-102	erythropoietin	Mus musculus	63-66
12766404-1	2003	Triple-resonance two-dimensional H6/H5(C4N)H and C6/C5(C4N)H experiments are described that provide through-bond H6/H5 or C6/C5 to imino/amino correlations in pyrimidine bases in (13)C,(15)N-labeled RNA.	Nitrogen	41-42	complement C6	Homo sapiens	113-124
32579360-20	2020	Overall, elimination of Fc N-linked glycosylation, to mitigate TfRMAb effector function side-effects, has a profound effect on the plasma exposure of TfRMAb-N292G-EPO at therapeutic as well as high doses (3-20 mg/kg).	Nitrogen	27-28	erythropoietin	Mus musculus	163-166
32346937-0	2020	N-glycosylation controls inflammatory licensing-triggered PD-L1 upregulation in human mesenchymal stromal cells.	Nitrogen	0-1	CD274 molecule	Homo sapiens	58-63
32346937-17	2020	It reveals for the first time that this adaptive process is accompanied by an enhanced N-glycosylation, which is a prerequisite for PD-L1 to be transported to the cell surface and to be secreted.	Nitrogen	87-88	CD274 molecule	Homo sapiens	132-137
32513868-6	2020	On the basis of screening for 20 soluble proteins that may be N-glycosylated in the ER in the ste24  strain, we identified the transcription factor Rme1 as a protein that is partially N-glycosylated despite the lack of a signal peptide.	Nitrogen	62-63	Rme1p	Saccharomyces cerevisiae S288C	148-152
32513868-6	2020	On the basis of screening for 20 soluble proteins that may be N-glycosylated in the ER in the ste24  strain, we identified the transcription factor Rme1 as a protein that is partially N-glycosylated despite the lack of a signal peptide.	Nitrogen	184-185	Rme1p	Saccharomyces cerevisiae S288C	148-152
32223162-1	2020	Lanthanide-based dinitrogen reduction chemistry has been expanded by the discovery of the first end-on Ln2(micro-eta1:eta1-N2) complexes.	Nitrogen	17-27	secreted phosphoprotein 1	Homo sapiens	113-117
32223162-1	2020	Lanthanide-based dinitrogen reduction chemistry has been expanded by the discovery of the first end-on Ln2(micro-eta1:eta1-N2) complexes.	Nitrogen	17-27	secreted phosphoprotein 1	Homo sapiens	118-122
32223162-3	2020	The isolated Ln(II) tris(amide) complex [K(crypt)][Tb(NR2)3] (crypt = 2.2.2-cryptand), 1-Tb, reacts with dinitrogen in Et2O at -35  C to form the end-on bridging dinitrogen complex [K(crypt)]2{[(R2N)3Tb]2[micro-eta1:eta1-N2]}, 2-Tb.	Nitrogen	105-115	secreted phosphoprotein 1	Homo sapiens	211-215
32223162-3	2020	The isolated Ln(II) tris(amide) complex [K(crypt)][Tb(NR2)3] (crypt = 2.2.2-cryptand), 1-Tb, reacts with dinitrogen in Et2O at -35  C to form the end-on bridging dinitrogen complex [K(crypt)]2{[(R2N)3Tb]2[micro-eta1:eta1-N2]}, 2-Tb.	Nitrogen	105-115	secreted phosphoprotein 1	Homo sapiens	216-220
32478736-0	2020	Nitrogen Compound Characterization in Fuels by Multidimensional Gas Chromatography.	Nitrogen	0-8	gastrin	Homo sapiens	64-67
32003902-7	2020	Furthermore, the close relationship between the EKT-MP2 method and the derivative approach of the MP2 energy with respect to the orbital occupation numbers [N.	Nitrogen	157-158	tryptase pseudogene 1	Homo sapiens	98-101
32708305-0	2020	Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N-Glycosylation.	Nitrogen	0-1	natural cytotoxicity triggering receptor 3	Homo sapiens	40-45
12689676-3	2003	The present study showed that V-ATPase is directly involved in the incorporation of risedronate, a nitrogen containing bisphosphonate, into osteoclasts.	Nitrogen	99-107	ATPase, H+ transporting, lysosomal V0 subunit D2	Mus musculus	30-38
32760387-0	2020	Expression of Formate-Tetrahydrofolate Ligase Did Not Improve Growth but Interferes With Nitrogen and Carbon Metabolism of Synechocystis sp.	Nitrogen	89-97	MEXAM1_RS01570	Methylobacterium extorquens AM1	14-45
32760387-10	2020	The data implied that ftl expression interfered with the signaling the carbon/nitrogen ratio in Synechocystis.	Nitrogen	78-86	MEXAM1_RS01570	Methylobacterium extorquens AM1	22-25
32203219-10	2020	CONCLUSIONS: Collectively, we demonstrate a critical role of O- and N-linked glycoTs in PC progression and delineate the mechanism encompassing the role of GCNT3 in PC.	Nitrogen	2-3	glucosaminyl (N-acetyl) transferase 3, mucin type	Homo sapiens	156-161
32032660-5	2020	The investigation of additional innate immunity elements revealed that A + N (or camptothecin) stimulated the expression of NLRX1, STING (stimulator of interferon genes) and two antiviral proteins, IFIT1 and IFIT3.	Nitrogen	75-76	interferon induced protein with tetratricopeptide repeats 3	Homo sapiens	208-213
12689676-11	2003	Inhibition of V-ATPase with bafilomycin A(1) also prevented disruption of actin rings by etidronate, a non-nitrogen-containing bisphosphonate.	Nitrogen	107-115	ATPase, H+ transporting, lysosomal V0 subunit D2	Mus musculus	14-22
32028541-7	2020	Finally, the more effective hydrazone formation technique of CBH was characterized and applied for N-linked glycan analysis by CE/LIF.	Nitrogen	99-100	LIF interleukin 6 family cytokine	Homo sapiens	130-133
12689676-12	2003	These results suggest that V-ATPase induced acidification beneath the ruffled borders of osteoclasts and subsequent bone demineralization triggers the incorporation of both nitrogen-containing and non-nitrogen-containing bisphosphonates into osteoclasts.	Nitrogen	173-181	ATPase, H+ transporting, lysosomal V0 subunit D2	Mus musculus	27-35
32844011-5	2020	The FeII atom is coordinated by two tridentate N-binding {H2B(3,5-(CH3)2-pz)(pypz)}- ligands.	Nitrogen	47-48	H2B clustered histone 21	Homo sapiens	58-61
12689676-12	2003	These results suggest that V-ATPase induced acidification beneath the ruffled borders of osteoclasts and subsequent bone demineralization triggers the incorporation of both nitrogen-containing and non-nitrogen-containing bisphosphonates into osteoclasts.	Nitrogen	201-209	ATPase, H+ transporting, lysosomal V0 subunit D2	Mus musculus	27-35
31710744-9	2020	We further show that the aggregation of two complexes is initiated by the association between the N-terminal domains of TNFR1 receptors.	Nitrogen	98-99	TNF receptor superfamily member 1A	Homo sapiens	120-125
12627182-6	2003	Lp(a) was consistently associated with diastolic blood pressure, systolic blood pressure, total protein, albumin and nitrogen excretion in the 40-60 y age group.	Nitrogen	117-125	lipoprotein(a)	Homo sapiens	0-5
32203650-1	2020	Metal-nitrogen-carbon (MNC) nanocomposites have been hailed as promising, efficient electrocatalysts toward oxygen reduction reaction (ORR) due to the formation of MNx coordination moieties.	Nitrogen	6-14	keratin 86	Homo sapiens	164-167
32685809-7	2020	The gas recirculating glass pump achieved a flow rate of >500 mL min-1 N2 against atmospheric pressure at 15 W peak power input and >100 mL min-1 N2 against a differential pressure of +6 in.	Nitrogen	71-73	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	4-7
32685809-7	2020	The gas recirculating glass pump achieved a flow rate of >500 mL min-1 N2 against atmospheric pressure at 15 W peak power input and >100 mL min-1 N2 against a differential pressure of +6 in.	Nitrogen	146-148	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	4-7
12615950-8	2003	Transport of (14)C-labeled urea by AtDUR3 in oocytes exhibited saturation kinetics with a K(m) of approximately 3 micro M. AtDUR3 was expressed in shoots and roots and upregulated during early germination and under nitrogen deficiency in roots.	Nitrogen	215-223	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	35-41
31402760-9	2020	Abbreviations DCCM dynamic cross-correlation mapping DMF N,N-dimethylformamide DSSP definition of secondary structure of proteins FOXO forkhead transcription factors MD molecular dynamics PCA principal component analysis PDB protein data bank PTKs protein tyrosine kinases PTPs protein tyrosine phosphatases PTP-MEG2 megakaryocyte protein tyrosine phosphatase 2 RIN residue interaction network RING Residue Interaction Network Generator RMSD root means square deviation RMSF root mean square fluctuation Communicated by Ramaswamy H. Sarma.	Nitrogen	57-58	protein tyrosine phosphatase non-receptor type 9	Homo sapiens	308-316
31982717-1	2020	A one-dimensional hybrid with N,P co-doped carbon nanowires threaded CoP nanoparticles is rationally fabricated by employing surface modified coordination polymers as a precursor.	Nitrogen	30-31	caspase recruitment domain family member 16	Homo sapiens	69-72
31982717-2	2020	Ultrasmall CoP nanoparticlesare well encapsulated in N,P co-doped carbon nanowires, which can effectively buffer the volume expansion of active CoP and facilitate fast lithium-ion/electron transfer during charge/discharge processes.	Nitrogen	53-54	caspase recruitment domain family member 16	Homo sapiens	11-14
31982717-2	2020	Ultrasmall CoP nanoparticlesare well encapsulated in N,P co-doped carbon nanowires, which can effectively buffer the volume expansion of active CoP and facilitate fast lithium-ion/electron transfer during charge/discharge processes.	Nitrogen	53-54	caspase recruitment domain family member 16	Homo sapiens	144-147
31915290-7	2020	Initiation is also elevated at certain NCCs initiating N-terminal extensions, including those that direct mitochondrial localization of the GRS1 and ALA1 products, and at a small set of main CDS AUG codons with especially poor context, including that of eIF1 itself.	Nitrogen	39-40	alanine--tRNA ligase	Saccharomyces cerevisiae S288C	149-153
31865509-8	2020	Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space.	Nitrogen	62-63	K+ efflux antiporter 1	Arabidopsis thaliana	57-61
31865509-8	2020	Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space.	Nitrogen	62-63	K+ efflux antiporter 1	Arabidopsis thaliana	131-135
31865509-8	2020	Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space.	Nitrogen	62-63	K+ efflux antiporter 1	Arabidopsis thaliana	131-135
31865509-8	2020	Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space.	Nitrogen	179-180	K+ efflux antiporter 1	Arabidopsis thaliana	57-61
31865509-8	2020	Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space.	Nitrogen	179-180	K+ efflux antiporter 1	Arabidopsis thaliana	131-135
31865509-8	2020	Using a newly designed antibody specific to the envelope KEA1 N-terminus and transgenic Arabidopsis plants expressing a C-terminal KEA1-YFP fusion protein, we show that both, the N-terminal and C-terminal, regulatory domains of KEA1 reside in the chloroplast stroma and not in the intermembrane space.	Nitrogen	179-180	K+ efflux antiporter 1	Arabidopsis thaliana	131-135
32225143-11	2020	Heterologously-expressed rhodopsin was observed on SDS-PAGE to have two different N-glycosylated populations, which would probably have hindered crystallogenesis.	Nitrogen	82-83	rhodopsin	Bos taurus	25-34
12615950-8	2003	Transport of (14)C-labeled urea by AtDUR3 in oocytes exhibited saturation kinetics with a K(m) of approximately 3 micro M. AtDUR3 was expressed in shoots and roots and upregulated during early germination and under nitrogen deficiency in roots.	Nitrogen	215-223	urea-proton symporter DEGRADATION OF UREA 3 (DUR3)	Arabidopsis thaliana	123-129
31810697-5	2020	We also described that N fertilizer alters the Cd exchange capacity and the bio-available Cd content in soil; regulates nitric oxide induced divalent cation gene expression of Nramp1, HMA2, and IRT1; and changes cell wall isolation, chelation capacity, and oxidative resistance to regulate Cd accumulation in plants.	Nitrogen	23-24	allograft inflammatory factor 1	Homo sapiens	194-198
31879129-2	2020	Although the Shank N-terminal domain and ankyrin repeats domain tandem (NTD-ANK) is known to bind to Ras and Rap1, the molecular mechanism underlying and functional significance of the bindings in synapses are unknown.	Nitrogen	19-20	RAP1A, member of RAS oncogene family	Homo sapiens	109-113
32361287-11	2020	By applying the procedure to oxygen (O2), carbon dioxide (CO2), methane (CH4), nitrous oxide (N2O) and nitrogen gas (N2) in an aerobic biological wastewater treatment reactor, it was demonstrated that some common simplifications can lead to significant errors, for which corrections were proposed.	Nitrogen	103-111	gastrin	Homo sapiens	112-115
12637241-18	2003	Correlation analysis suggested that CYP2B11 catalyses the N-demethylation of dextromethorphan (mediated in humans by CYP3A) and the 4"-hydroxylation of mephenytoin (mediated in humans by CYP2C19) in the dog, and that this enzyme and CYP3A12 contribute to S-warfarin 7-hydroxylation (mediated in humans by CYP2C9).	Nitrogen	58-59	cytochrome P450 2B11	Canis lupus familiaris	36-43
32222503-4	2020	In the RBS process, the migration of biochar nitrogen to plants was significantly greater than that of straw nitrogen, and it showed an overall decreasing trend with the increase in pyrolysis temperature, but was less influenced by the pyrolysis atmosphere.	Nitrogen	45-53	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	7-10
32222503-4	2020	In the RBS process, the migration of biochar nitrogen to plants was significantly greater than that of straw nitrogen, and it showed an overall decreasing trend with the increase in pyrolysis temperature, but was less influenced by the pyrolysis atmosphere.	Nitrogen	109-117	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	7-10
32441519-6	2020	CO2 and N2 were not complementary but competitive in replacing CH4 in the small (512) cages, which contributed to maintenance of the cage stability of the initial sII hydrate and, thus, resulted in a lower extent of replacement.	Nitrogen	8-10	transcription elongation factor A1	Homo sapiens	163-166
31931118-1	2020	Unlike gonadotropin-releasing hormone (GnRH) analogues characterized by amino acid replacement in decapeptide primary structure, Cu-GnRH molecule preserves the native sequence but contains a Cu2+ ion stably bound to the nitrogen atoms including that of the imidazole ring of His2.	Nitrogen	220-228	gonadotropin releasing hormone 1	Rattus norvegicus	132-136
12637241-18	2003	Correlation analysis suggested that CYP2B11 catalyses the N-demethylation of dextromethorphan (mediated in humans by CYP3A) and the 4"-hydroxylation of mephenytoin (mediated in humans by CYP2C19) in the dog, and that this enzyme and CYP3A12 contribute to S-warfarin 7-hydroxylation (mediated in humans by CYP2C9).	Nitrogen	58-59	cytochrome P450 3A12	Canis lupus familiaris	233-240
31980228-2	2020	Facilitative urea transporter-B proteins are known to be involved in urea transport across the rumen epithelium and thus efficiently facilitate the urea nitrogen salvaging process.	Nitrogen	153-161	solute carrier family 14 member 1	Bos taurus	13-31
12527701-5	2003	Fluorometry was used to measure N-alkylPP formation following interaction of porphyrinogenic xenobiotics and NADPH with cDNA-expressed human P450 enzymes in microsomes from HLCL or BIICL.	Nitrogen	32-33	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	141-145
32479276-5	2020	159 tons of nitrogen and 26.4 tons of phosphorus were estimated to be discharged to the Baltic Sea annually.	Nitrogen	12-20	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	95-98
32479276-7	2020	Nitrogen and phosphorus input from grey water contributes to 0.25% of the exceedance of, for the Baltic Sea set, eutrophication target.	Nitrogen	0-8	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	104-107
31962012-7	2020	Indeed, only one variant, in the conserved N-terminal zinc finger of GATA4, was considered pathogenic, with functional analysis confirming differences in its ability to regulate Sox9 and AMH and in protein interaction with ZFPM2.	Nitrogen	43-44	anti-Mullerian hormone	Homo sapiens	187-190
31740367-0	2020	N-terminal fusion of the N-terminal domain of bacterial enzyme I facilitates recombinant expression and purification of the human RNA demethylases FTO and Alkbh5.	Nitrogen	0-1	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	147-150
31740367-0	2020	N-terminal fusion of the N-terminal domain of bacterial enzyme I facilitates recombinant expression and purification of the human RNA demethylases FTO and Alkbh5.	Nitrogen	25-26	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	147-150
31785340-4	2020	N-terminal His6 tagged Cre recombinase obtained was approximately 26 fold purified and promoted the site-specific recombination of two loxP sites of linearized pLox2+ vector allowing the excision of a re-circularized plasmid and a short stretch of DNA containing the recombined loxP site.	Nitrogen	0-1	site-specific integrase	Escherichia phage P1	23-26
32545869-6	2020	Partial ablation of the Arg/N-degron pathway greatly increases IL-1beta secretion, indicating the importance of this ubiquitous pathway in the initiation and resolution of inflammation.	Nitrogen	28-29	interleukin 1 alpha	Homo sapiens	63-71
32401514-1	2020	Until now, reactions between methane photolysis products (CH3 , CH2) and active N atom or reactive NO radical are proposed as routes of HCN formation in prebiotic earth.	Nitrogen	80-81	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	136-139
32487741-8	2020	The ratio of C/N was linearly related with the concentrations of DCA and LCA and gene expression levels of ZO-1, occludin, and EGFR.	Nitrogen	15-16	zonula occludens 1	Sus scrofa	107-111
32487741-8	2020	The ratio of C/N was linearly related with the concentrations of DCA and LCA and gene expression levels of ZO-1, occludin, and EGFR.	Nitrogen	15-16	occludin	Sus scrofa	113-121
32017353-9	2020	Furthermore, HBV encountered the Sec24A/Sec23B complex via an interaction that involved the N-terminal half of Sec24A and a di-arginine motif of its S domain, mirroring a novel ER export code.	Nitrogen	92-93	SEC23 homolog B, COPII coat complex component	Homo sapiens	40-46
31919097-3	2020	In this study, we have developed a unique fusion technique using microtubule-associated protein 1A/1B light chain 3B, a key marker protein of autophagy, to tag the N-terminus of the proteins involved in the N-degron pathway, which enables high yield of homogeneous target proteins with variable N-terminal residues for diverse biochemical studies including enzymatic and binding assays and substrate identification.	Nitrogen	164-165	microtubule associated protein 1A	Homo sapiens	65-101
31919097-3	2020	In this study, we have developed a unique fusion technique using microtubule-associated protein 1A/1B light chain 3B, a key marker protein of autophagy, to tag the N-terminus of the proteins involved in the N-degron pathway, which enables high yield of homogeneous target proteins with variable N-terminal residues for diverse biochemical studies including enzymatic and binding assays and substrate identification.	Nitrogen	207-208	microtubule associated protein 1A	Homo sapiens	65-101
12441343-5	2003	Pancreasin cDNA predicts a 290-residue, N-glycosylated, serine peptidase with a typical signal peptide, a 12-residue activation peptide cleaved by tryptic hydrolysis, and a 256-amino acid catalytic domain.	Nitrogen	13-14	serine protease 27	Homo sapiens	0-10
31919097-3	2020	In this study, we have developed a unique fusion technique using microtubule-associated protein 1A/1B light chain 3B, a key marker protein of autophagy, to tag the N-terminus of the proteins involved in the N-degron pathway, which enables high yield of homogeneous target proteins with variable N-terminal residues for diverse biochemical studies including enzymatic and binding assays and substrate identification.	Nitrogen	207-208	microtubule associated protein 1A	Homo sapiens	65-101
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	12-20	transmembrane protein 132A	Homo sapiens	97-100
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	54-62	transmembrane protein 132A	Homo sapiens	97-100
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	54-62	transmembrane protein 132A	Homo sapiens	97-100
32111063-1	2020	Purines are nitrogen compounds consisting mainly of a nitrogen base of adenine (ABP) or guanine (GBP) and their derivatives: nucleosides (nitrogen bases plus ribose) and nucleotides (nitrogen bases plus ribose and phosphate).	Nitrogen	54-62	transmembrane protein 132A	Homo sapiens	97-100
31927217-4	2020	Other examples of cross-talk between PTMs also exist, such as PSGL-1, where the combined presence of N-terminal sulfotyrosines and O-glycans is pivotal for selectin binding.	Nitrogen	101-102	selectin P ligand	Homo sapiens	62-68
32108991-0	2020	Investigating the clearance of VWF A-domains using site-directed PEGylation and novel N-linked glycosylation.	Nitrogen	86-87	Von Willebrand factor	Mus musculus	31-34
32203567-7	2020	Additionally, treatment with either ICG-001 or E7386, which are both small molecule inhibitors of beta-catenin/CBP signaling, leads to increased transcriptional expression of fucosyltransferases FUT2 and FUT3, with a concomitant increase in EGFR N-glycan antennary fucosylation.	Nitrogen	246-247	catenin beta 1	Homo sapiens	98-110
12421832-11	2003	We also show that of 13 potential sites for N-linked carbohydrate substitution of the PAPP-A subunit, 11 are occupied.	Nitrogen	44-45	pappalysin 1	Homo sapiens	86-92
32203567-7	2020	Additionally, treatment with either ICG-001 or E7386, which are both small molecule inhibitors of beta-catenin/CBP signaling, leads to increased transcriptional expression of fucosyltransferases FUT2 and FUT3, with a concomitant increase in EGFR N-glycan antennary fucosylation.	Nitrogen	246-247	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	204-208
32486402-4	2020	The maximum nitrogen and pearlite contents were obtained after 20 min of nitrogen gas injection, and the corresponding tensile strength and elongation of the DI were calculated as 492 MPa and 9.5%, respectively, which were 9.3% and 22% higher than those of the DI prepared without the nitrogen gas injection treatment, respectively.	Nitrogen	73-81	gastrin	Homo sapiens	82-85
32149134-2	2020	Mature CD147 is an N-linked glycosylated protein and exists on the transmembrane and as soluble forms in tumors.	Nitrogen	19-20	basigin (Ok blood group)	Homo sapiens	7-12
32069989-4	2020	Flow cytometry analysis of annexin V-FITC/propidium iodide indicated that colicin N primarily induced apoptosis in human lung cancer cells.	Nitrogen	74-83	annexin A5	Homo sapiens	27-36
12527193-8	2003	Mouse and human CRB3 have identical intracellular domains but divergent extracellular domains except for a conserved N-glycosylation site.	Nitrogen	117-118	crumbs cell polarity complex component 3	Homo sapiens	16-20
31974312-7	2020	NMR studies further revealed that the N-terminal part of the Spp2 G-patch, which is the most conserved region in different G-patch proteins, transiently samples helical conformations, possibly facilitating a conformational selection binding mechanism.	Nitrogen	0-1	secreted phosphoprotein 2	Homo sapiens	61-65
32042062-0	2020	Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK.	Nitrogen	20-21	huntingtin interacting protein K	Homo sapiens	79-83
32042062-1	2020	The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity.	Nitrogen	10-11	N-alpha-acetyltransferase 50, NatE catalytic subunit	Homo sapiens	67-72
32042062-1	2020	The human N-terminal acetyltransferase E (NatE) contains NAA10 and NAA50 catalytic, and NAA15 auxiliary subunits and associates with HYPK, a protein with intrinsic NAA10 inhibitory activity.	Nitrogen	10-11	huntingtin interacting protein K	Homo sapiens	133-137
32042062-8	2020	These studies reveal the molecular basis for coordinated N-terminal acetylation by NatE and HYPK.	Nitrogen	57-58	huntingtin interacting protein K	Homo sapiens	92-96
32028989-9	2020	Lastly, we found that GFP+/Iba1+ cells from young and old donors were differentially polarized to an anti- and pro-inflammatory phenotype and produced neuroprotective factors and reactive nitrogen species in vivo, respectively.	Nitrogen	188-196	induction of brown adipocytes 1	Mus musculus	27-31
32366087-2	2020	The hydrogel exhibited a reversible gas-responsive property upon N2/CO2 exchange.	Nitrogen	65-67	gastrin	Homo sapiens	36-39
32455892-3	2020	We demonstrate the coexistence of filamentary (abrupt) and interface (homogeneous) switching of Ni/SiN/BN/n++-Si devices.	Nitrogen	7-8	embryonal Fyn-associated substrate	Homo sapiens	99-102
31945497-4	2020	The dramatically upregulated gene indoleamine 2, 3-dioxygenase 1 (IDO1) after AIH was identified, and its role in generation of ferroptosis and reactive nitrogen species (RNS) was assessed both in vitro and in vivo by genetic deletion or pharmacologic inhibition of IDO1.	Nitrogen	153-161	indoleamine 2,3-dioxygenase 1	Mus musculus	34-64
31945497-4	2020	The dramatically upregulated gene indoleamine 2, 3-dioxygenase 1 (IDO1) after AIH was identified, and its role in generation of ferroptosis and reactive nitrogen species (RNS) was assessed both in vitro and in vivo by genetic deletion or pharmacologic inhibition of IDO1.	Nitrogen	153-161	indoleamine 2,3-dioxygenase 1	Mus musculus	66-70
12558316-7	2003	The lowest value of pHi during CPB was significantly related to blood urea nitrogen (r = -0.75, p &lt; 0.05), serum creatinine (r = -0.78, p &lt; 0.05), creatinine clearance (r = 0.68, p &lt; 0.05) on postoperative day 1, and blood urea nitrogen (r = -0.84, p &lt; 0.01) on day 3.	Nitrogen	75-83	glucose-6-phosphate isomerase	Homo sapiens	20-23
32414460-12	2020	It is concluded that insulin response to RPG was decreased relative to the control and RPG supplementation linearly increased crude protein intake and milk urea nitrogen with increasing dose, but did not affect concentrations of progesterone, milk yield, or dry matter intake.	Nitrogen	161-169	insulin	Bos taurus	21-28
31863529-3	2020	N-terminal proline exists in more than 300 proteins in Saccharomyces cerevisiae, but only three of them are the gluconeogenic enzymes; isocitrate lyase (Icl1), fructose-1,6-bisphosphatase (Fbp1), and malate dehydrogenase (Mdh2).	Nitrogen	0-1	malate dehydrogenase MDH2	Saccharomyces cerevisiae S288C	222-226
32041314-7	2020	The activities of nitrate reductase, glutamine synthetase and glutamate synthase that are involved in nitrogen metabolism were downregulated by shading stresses.	Nitrogen	102-110	nitrate reductase [NADH] 1	Zea mays	18-35
31895557-3	2020	In Saccharomyces cerevisiae and other Saccharomyces yeasts, the gluconeogenic enzymes Fbp1, Icl1, and Mdh2 bear Nt-Pro and are conditionally destroyed by the Pro/N-degron pathway.	Nitrogen	112-113	malate dehydrogenase MDH2	Saccharomyces cerevisiae S288C	102-106
31895557-6	2020	One question to be addressed was whether the presence of non-Pro Nt residues in K. lactis Fbp1, Icl1, and Mdh2 was accompanied, on evolutionary time scales (S. cerevisiae and K. lactis diverged ~150 million years ago), by a changed specificity of the Gid4 N-recognin.	Nitrogen	65-66	malate dehydrogenase MDH2	Saccharomyces cerevisiae S288C	106-110
12558316-7	2003	The lowest value of pHi during CPB was significantly related to blood urea nitrogen (r = -0.75, p &lt; 0.05), serum creatinine (r = -0.78, p &lt; 0.05), creatinine clearance (r = 0.68, p &lt; 0.05) on postoperative day 1, and blood urea nitrogen (r = -0.84, p &lt; 0.01) on day 3.	Nitrogen	237-245	glucose-6-phosphate isomerase	Homo sapiens	20-23
32019925-2	2020	Here we identify a novel and critical function of IKK2 and its co-factor NEMO in the activation of oncogenic c-Jun N-terminal kinase (JNK) signaling, induced by the latent membrane protein 1 (LMP1) of Epstein-Barr virus (EBV).	Nitrogen	73-74	inhibitor of nuclear factor kappa B kinase subunit beta	Homo sapiens	50-54
12519691-10	2003	However, other cytochrome P450 enzymes (CYP2E1 and CYP2B6) also appear to play a role in the N-oxidation of this drug.	Nitrogen	93-94	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	51-57
31786226-0	2020	Highly effective methods for expression/purification of recombinant human HSP90 and its four distinct (N-LR-M-C) domains.	Nitrogen	103-104	heat shock protein 90 alpha family class A member 1	Homo sapiens	74-79
32334520-7	2020	Spearman"s rank correlation analysis demonstrated that the concentrations of circulating HSP27 were positively associated with carotid IMT (r = 0.198, P = 0.007) and blood urea nitrogen (r = 0.170, P < 0.05).	Nitrogen	177-185	heat shock protein family B (small) member 1	Homo sapiens	89-94
31786226-1	2020	Heat shock protein 90 (HSP90) plays essential roles in the normal physiology and comprises four distinct domains, including NH2-terminal (N), charged linker region (LR), middle (M), and COOH-terminal (C) domains, all of which regulate HSP90 biological functions.	Nitrogen	124-125	heat shock protein 90 alpha family class A member 1	Homo sapiens	0-21
12504579-3	2002	Among the major genetic changes required for infection of intestinal cells and CD4 independence, two potential N-glycosylation sites appeared as a result of the extension of five amino acids in the V1/V2 region and three amino acid changes ((296)KYT --&gt; (296)NNI) were identified in the V3 loop of HIV-1 iNDK gp120.	Nitrogen	111-112	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	312-317
31786226-1	2020	Heat shock protein 90 (HSP90) plays essential roles in the normal physiology and comprises four distinct domains, including NH2-terminal (N), charged linker region (LR), middle (M), and COOH-terminal (C) domains, all of which regulate HSP90 biological functions.	Nitrogen	124-125	heat shock protein 90 alpha family class A member 1	Homo sapiens	23-28
31786226-3	2020	cDNAs encoding FL, N, LR, M and C domains of human HSP90alpha were amplified and cloned into pET-32b(+) expression vector.	Nitrogen	2-3	heat shock protein 90 alpha family class A member 1	Homo sapiens	51-61
31846774-2	2020	In the present study, two IRAK family members, OnIRAK1 and OnIRAK4, were identified in the Nile tilapia Oreochromis niloticus with a conserved N-terminal death domain and a protein kinase domain, similar to those of other fishes and mammals.	Nitrogen	91-92	interleukin-1 receptor-associated kinase 4	Oreochromis niloticus	59-66
31657228-1	2020	SIGNIFICANCE: Most brains affected by neurodegenerative diseases manifest mitochondrial dysfunction as well as elevated production of reactive oxygen and nitrogen species (ROS/RNS), contributing to synapse loss and neuronal injury.	Nitrogen	154-162	FAM20C golgi associated secretory pathway kinase	Homo sapiens	176-179
32317656-0	2020	Nitrogen enrichment increases greenhouse gas emissions from emerged intertidal sandflats.	Nitrogen	0-8	gastrin	Homo sapiens	41-44
12171601-1	2002	We have analysed the role of N-linked glycosylation in regulating human proteinase-activated receptor-2 (hPAR(2)) expression and function.	Nitrogen	29-30	F2R like trypsin receptor 1	Homo sapiens	72-103
32344277-3	2020	The aim of this work is to clarify the role of NF-kB activation in production of reactive nitrogen and oxygen species, activity of antioxidant enzymes and intensity of lipid peroxidation (LPO) in gastric mucosa of rats during chronic fluoride intoxication.	Nitrogen	90-98	nuclear factor kappa B subunit 1	Rattus norvegicus	47-52
32316603-12	2020	Both human OST complexes, OST-A (with STT3A) and OST-B (containing STT3B), are involved in the N-linked glycosylation of proteins in the ER.	Nitrogen	95-96	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	38-43
32316603-12	2020	Both human OST complexes, OST-A (with STT3A) and OST-B (containing STT3B), are involved in the N-linked glycosylation of proteins in the ER.	Nitrogen	95-96	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	67-72
32212616-2	2020	Herein, we address this challenge by developing a rapid electrochemical expansion strategy for scale preparation of fine crystal quality BPNSs from bulk black phosphorus, which was demonstrated to be an active cocatalyst for photocatalytic nitrogen fixation in the presence of CdS as a photocatalyst.	Nitrogen	240-248	CDP-diacylglycerol synthase 1	Homo sapiens	277-280
32212616-3	2020	The transient photocurrent and charge density studies show that the BPNSs can efficiently accelerate charge separation of CdS, leading to the enhanced photocatalytic activities of BPNSs/CdS nanocomposites for nitrogen fixation.	Nitrogen	209-217	CDP-diacylglycerol synthase 1	Homo sapiens	122-125
31778870-4	2020	The surface removal rate and removal efficiency of ammonium nitrogen in the SFCWs using the probabilistic approach were 0.27-3.23 g m-2 d-1 and 43.0-99.9% (95% confidence interval (CI)), which were consistent with the deterministic approach (95% CI: 0.24-3.18 g m-2 d-1 and 70.4-99.9%).	Nitrogen	51-68	iodothyronine deiodinase 1	Sus scrofa	136-139
31778870-4	2020	The surface removal rate and removal efficiency of ammonium nitrogen in the SFCWs using the probabilistic approach were 0.27-3.23 g m-2 d-1 and 43.0-99.9% (95% confidence interval (CI)), which were consistent with the deterministic approach (95% CI: 0.24-3.18 g m-2 d-1 and 70.4-99.9%).	Nitrogen	51-68	iodothyronine deiodinase 1	Sus scrofa	266-269
31989273-2	2020	The results show that the thermally controlled diastereoselective [3 + 2] cycloaddition reaction between quinolinium imide and methyl acrylate provides two regio-isomers: 1,4-regioisomer (N-C1, C-C2) and 1,3-regioisomer (N-C2, C-C1).	Nitrogen	188-189	C-C motif chemokine ligand 14	Homo sapiens	227-231
31926151-0	2020	Eugenol restricts Cancer Stem Cell population by degradation of beta-catenin via N-terminal Ser37 phosphorylation-an in vivo and in vitro experimental evaluation.	Nitrogen	81-82	catenin beta 1	Homo sapiens	64-76
31926151-5	2020	The in-depth analysis revealed the downregulation of beta-catenin thereby facilitating its degradation by N-terminal phosphorylation of Ser37 residue.	Nitrogen	106-107	catenin beta 1	Homo sapiens	53-65
32212616-3	2020	The transient photocurrent and charge density studies show that the BPNSs can efficiently accelerate charge separation of CdS, leading to the enhanced photocatalytic activities of BPNSs/CdS nanocomposites for nitrogen fixation.	Nitrogen	209-217	CDP-diacylglycerol synthase 1	Homo sapiens	186-189
32212616-4	2020	The 1.5% BPNSs/CdS photocatalyst exhibits the highest photocatalytic activity for nitrogen fixation with a NH3 evolution rate of 61.63 mumol L-1 h-1.	Nitrogen	82-90	CDP-diacylglycerol synthase 1	Homo sapiens	15-18
12171601-1	2002	We have analysed the role of N-linked glycosylation in regulating human proteinase-activated receptor-2 (hPAR(2)) expression and function.	Nitrogen	29-30	F2R like trypsin receptor 1	Homo sapiens	105-112
12171601-11	2002	We conclude that hPAR(2) N-linked glycosylation and sialylation regulates receptor expression and/or signalling.	Nitrogen	25-26	F2R like trypsin receptor 1	Homo sapiens	17-24
32154085-3	2020	This study reports that the Co-based coordination polymer (ZIF-67) anchoring on an indium-organic framework (InOF-1) composite (InOF-1@ZIF-67) is treated followed by carbonization and phosphorization to successfully obtain CoP nanoparticles-embedded carbon nanotubes and nitrogen-doped carbon materials (CoP-InNC@CNT).	Nitrogen	271-279	caspase recruitment domain family member 16	Homo sapiens	223-226
32019022-6	2020	Specifically, biochar properties including pH, cation exchange capacity (CEC), contents of carbon and ash, bulk density, and soil conditions including texture, pH, CEC, nitrogen content, and C/N ratio significantly affected the results of PPR to biochar addition.	Nitrogen	169-177	PPR1	Homo sapiens	239-242
12433806-3	2002	Kinetics evidence is presented that the N-depropylation of (-)-OSU6162 in human hepatic microsomes is mediated by multiple cytochrome p450 (p450) enzymes, in particular CYP2D6.	Nitrogen	40-41	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	134-138
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	172-173	protein phosphatase 4 catalytic subunit	Homo sapiens	17-21
12433806-3	2002	Kinetics evidence is presented that the N-depropylation of (-)-OSU6162 in human hepatic microsomes is mediated by multiple cytochrome p450 (p450) enzymes, in particular CYP2D6.	Nitrogen	40-41	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	140-144
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	172-173	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	172-173	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
12130643-0	2002	Complex N-linked glycosylated nicastrin associates with active gamma-secretase and undergoes tight cellular regulation.	Nitrogen	8-9	nicastrin	Homo sapiens	30-39
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	17-21
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	17-21
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	17-21
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31913025-2	2020	Treatment of [Ir(PPh3)3Cl] prepared by a convenient method with Hdpp in the presence of KOtBu under the refluxing mixture solvent toluene/methanol (2:1, v/v) generates the N,N-chelating complex [Ir(K2N,N-dpp)(H)(Cl)(PPh3)2] (3) together with 1 and the N,N-chelating dihydride complex [Ir(K2N,N-dpp)(H)2(PPh3)2] (4).	Nitrogen	174-175	protein phosphatase 4 catalytic subunit	Homo sapiens	216-220
31963646-6	2020	This work was based on the crystal structure of the BTLA/HVEM complex showing that BTLA binds the N-terminal cysteine-rich domain of HVEM.	Nitrogen	98-99	B and T lymphocyte associated	Homo sapiens	52-56
31963646-6	2020	This work was based on the crystal structure of the BTLA/HVEM complex showing that BTLA binds the N-terminal cysteine-rich domain of HVEM.	Nitrogen	98-99	B and T lymphocyte associated	Homo sapiens	83-87
12070147-4	2002	When the lysine residue at the putative ubiquitination site of the N-degron was substituted with arginine, both the protein level and half-life of mutant Gts1p increased.	Nitrogen	67-68	Gts1p	Saccharomyces cerevisiae S288C	154-159
31879348-6	2020	We show that ESCO2 contains multiple PCNA-interaction motifs in its N terminus, each of which is essential to its ability to establish cohesion.	Nitrogen	39-40	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	13-18
31892537-6	2020	The LDB1 dimerization domain (DD) contains an N-terminal nuclear transport factor 2 (NTF2)-like subdomain and a small helix 4-helix 5 subdomain, which together form the LDB1 dimerization interface.	Nitrogen	46-47	LIM domain binding 1	Homo sapiens	4-8
12207487-3	2002	Combinations of hydrolysis and incubation with TGase generated products displaying novel physicochemical and nitrogen solubility properties.	Nitrogen	109-117	transglutaminase 1	Homo sapiens	47-52
12167564-9	2002	It would appear that the same, as yet unexamined, UGT catalyzes the N-glucuronidation of both cotinine and nicotine.	Nitrogen	68-69	UDP glucuronosyltransferase family 1 member A complex locus	Homo sapiens	50-53
12587735-4	2002	Reduced glutathione content and the activity of glutathione peroxidase and glutathione reductase increased with increase in oxygen concentration under nitrogen fixing conditions but decreased under anaerobic and nitrogenase repressed conditions.	Nitrogen	151-159	glutathione-disulfide reductase	Homo sapiens	75-96
12175915-7	2002	Insertion of a consensus N-glycosylation site [NX(S/T)] into putative loops 5/6, 8/9, and 9/10 of deglycosylated RFC-Gln(58) had minimal effects on MTX transport.	Nitrogen	25-26	solute carrier family 19 member 1	Homo sapiens	113-116
12190488-2	2002	It is, however, not recognized that the same amount of N can also qualitatively alter the electronic behavior of hydrogen: First-principles calculations reveal that, in GaAsN, a H atom bonds to N and can act as a donor in its own right, whereas in GaAs and GaN, H is amphoteric, causing passivation instead.	Nitrogen	55-56	gigaxonin	Homo sapiens	257-260
12435857-6	2002	In contrast to its fully glycosylated wild-type mature protein, the mutant THTR-1 protein underwent only the initial stage of N-linked glycosylation.	Nitrogen	126-127	solute carrier family 19 member 2	Homo sapiens	75-81
11991952-4	2002	Previously, we used N-glycosylation substitution mutants to map the extracellular topology of a weak inwardly rectifying K+ channel, Kir1.1 or ROMK1, and found that the entire H5 segment was extracellular.	Nitrogen	20-21	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	133-139
11991952-5	2002	We now report utilization of introduced N-glycosylation sites, NX(S/T), at positions Ser(128) in E1, and Gln(140), Ileu(143), and Phe(147) in the H5 sequence of a strong inwardly rectifying K+ channel, Kir2.1.	Nitrogen	40-41	potassium inwardly rectifying channel subfamily J member 2	Homo sapiens	202-208
12065289-7	2002	Mutations of the two potential N-linked glycosylation sites (N63Q, N314Q) of SLC19A2 did not affect functional activity; they did, however, lead to a noticeable reduction in apparent molecular weight of protein.	Nitrogen	31-32	solute carrier family 19 member 2	Homo sapiens	77-84
12163130-5	2002	The extracellular domains of LOX-1 are post-translationally modified by N-linked glycosylation.	Nitrogen	72-73	oxidized low density lipoprotein receptor 1	Homo sapiens	29-34
12057761-6	2002	Here we briefly review the role of IRP in iron-mediated damage induced by oxygen radicals, nitrogen-centered reactive species, and xenobiotics of pharmacological and clinical interest.	Nitrogen	91-99	Wnt family member 2	Homo sapiens	35-38
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	Gat1p	Saccharomyces cerevisiae S288C	104-108
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	Gat1p	Saccharomyces cerevisiae S288C	253-258
12075795-0	2002	Atmospheric chemistry of HFE-7500 [n-C3F7CF(OC2H5)CF(CF3)2]: reaction with OH radicals and Cl atoms and atmospheric fate of n-C3F7CF(OCHO*)CF(CF3)2 and n-C3F7CF(OCH2CH2O*)CF(CF3)2 radicals.	Nitrogen	35-36	homeostatic iron regulator	Homo sapiens	25-28
12075816-3	2002	When used in liquid/liquid extraction of Hg2+ and Cd2+ from aqueous solutions, the metal ion distribution ratios increased several orders of magnitude, regardless of whether the ionic liquids were used as the sole extracting phase or doped into a series of [1-alkyl-3-methylimidazolium][PF6] (alkyl = n-C4-C8) ionic liquids to form a 1:1 solution.	Nitrogen	3-4	sperm associated antigen 17	Homo sapiens	287-290
31901557-3	2020	In this study, Sp-CBL containing CBL-N, CBL-2, CBL-3 and RING domains was identified in mud crab Scylla paramamosain.	Nitrogen	37-38	Cbl proto-oncogene	Homo sapiens	18-21
31901557-3	2020	In this study, Sp-CBL containing CBL-N, CBL-2, CBL-3 and RING domains was identified in mud crab Scylla paramamosain.	Nitrogen	37-38	Cbl proto-oncogene	Homo sapiens	33-36
31901557-3	2020	In this study, Sp-CBL containing CBL-N, CBL-2, CBL-3 and RING domains was identified in mud crab Scylla paramamosain.	Nitrogen	37-38	Cbl proto-oncogene	Homo sapiens	33-36
31901557-3	2020	In this study, Sp-CBL containing CBL-N, CBL-2, CBL-3 and RING domains was identified in mud crab Scylla paramamosain.	Nitrogen	37-38	Cbl proto-oncogene	Homo sapiens	33-36
32067268-6	2020	TAZ directly associated with the N-terminal region of NR4A1 and substantially suppressed its DNA-binding and transcriptional activities.	Nitrogen	33-34	nuclear receptor subfamily 4, group A, member 1	Mus musculus	54-59
12162998-2	2002	Whereas IGFBP-1 and IGFBP-2 are not glycosylated, IGFBP-3 and IGFBP-4 are N-glycosylated and IGFBP-5 and IGFBP-6 are O-glycosylated.	Nitrogen	74-75	insulin-like growth factor binding protein 4	Rattus norvegicus	62-69
31603583-3	2020	Both MSI proteins contain two N-terminal RNA recognition motifs and play roles in post-transcriptional regulation of target mRNAs.	Nitrogen	30-31	RB binding protein 4, chromatin remodeling factor	Homo sapiens	5-8
12068109-10	2002	As such, the cytosolic AAT2 isoenzyme appears to serve a nonredundant function in plant nitrogen metabolism of Asp and Asp-derived amino acids.	Nitrogen	88-96	aspartate aminotransferase 2	Arabidopsis thaliana	23-27
31877421-2	2020	In this regard, in the present work a three-dimensional Fe2TiO5/nitrogen-doped graphene (denoted as 3D FTO/NG) hybrid electrocatalyst was synthesized via a facile in-situ process using a hydrothermal method.	Nitrogen	64-72	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	103-106
31998679-0	2019	One-Step Synthesis of N, P-Codoped Carbon Nanosheets Encapsulated CoP Particles for Highly Efficient Oxygen Evolution Reaction.	Nitrogen	22-23	caspase recruitment domain family member 16	Homo sapiens	66-69
31998679-3	2019	In this work, we have constructed a new material, CoP nanoparticles, which are encapsulated by a biomolecule-derived N, P-codoped carbon nanosheets via a simple and facile one-step strategy.	Nitrogen	117-118	caspase recruitment domain family member 16	Homo sapiens	50-53
31998679-6	2019	Moreover, the coverage of N, P-doped carbon can prevent the CoP nanoparticles from corrosion under the harsh reaction medium to achieve high and stable activity.	Nitrogen	26-27	caspase recruitment domain family member 16	Homo sapiens	60-63
31663736-2	2020	Clinical Hsp90 inhibitors bind to the ATP pocket in the N-terminal domain of Hsp90 and subsequently suppress the ATPase activity of Hsp90.	Nitrogen	56-57	heat shock protein 90 alpha family class A member 1	Homo sapiens	9-14
12091723-0	2002	C : N ratio increases in the phloem sap during floral transition of the long-day plants Sinapis alba and Arabidopsis thaliana.	Nitrogen	4-5	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	36-39
31663736-2	2020	Clinical Hsp90 inhibitors bind to the ATP pocket in the N-terminal domain of Hsp90 and subsequently suppress the ATPase activity of Hsp90.	Nitrogen	56-57	heat shock protein 90 alpha family class A member 1	Homo sapiens	77-82
31663736-2	2020	Clinical Hsp90 inhibitors bind to the ATP pocket in the N-terminal domain of Hsp90 and subsequently suppress the ATPase activity of Hsp90.	Nitrogen	56-57	heat shock protein 90 alpha family class A member 1	Homo sapiens	77-82
31866290-1	2020	Dipeptidyl peptidase IV (DPP-IV) is an aminopeptidase that cleaves the N-terminal dipeptide from peptides bearing proline or alanine residues.	Nitrogen	71-72	dipeptidyl peptidase 4	Homo sapiens	0-23
31866290-1	2020	Dipeptidyl peptidase IV (DPP-IV) is an aminopeptidase that cleaves the N-terminal dipeptide from peptides bearing proline or alanine residues.	Nitrogen	71-72	dipeptidyl peptidase 4	Homo sapiens	25-31
31860313-0	2020	Correction to "Calculation of 15N NMR Chemical Shifts in a Diversity of Nitrogen-Containing Compounds Using Composite Method Approximation at the DFT, MP2, and CCSD Levels".	Nitrogen	30-33	tryptase pseudogene 1	Homo sapiens	151-154
31860313-0	2020	Correction to "Calculation of 15N NMR Chemical Shifts in a Diversity of Nitrogen-Containing Compounds Using Composite Method Approximation at the DFT, MP2, and CCSD Levels".	Nitrogen	72-80	tryptase pseudogene 1	Homo sapiens	151-154
31919731-3	2020	Here, we successfully introduced N, C co-doped MoP (MoP-NC) nanoparticles by a simple and efficient two-step synthesis method using urea as a carbon source into the molybdenum phosphide system.	Nitrogen	33-34	opioid receptor mu 1	Homo sapiens	47-50
31919731-3	2020	Here, we successfully introduced N, C co-doped MoP (MoP-NC) nanoparticles by a simple and efficient two-step synthesis method using urea as a carbon source into the molybdenum phosphide system.	Nitrogen	33-34	opioid receptor mu 1	Homo sapiens	52-58
31919731-4	2020	The cheapness of urea and the excellent carbon to nitrogen ratio remove the obstacles ahead of the development of MoP-NC composites.	Nitrogen	50-58	opioid receptor mu 1	Homo sapiens	114-120
12091723-3	2002	In both species, the C : N ratio of the phloem sap increased markedly and early during the inductive treatment, suggesting that an inequality in organic C and N supply to the apical meristem may be important at floral transition.	Nitrogen	25-26	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	47-50
32004937-6	2020	However, the presence of two nitrogen atoms resulted in compounds with lower affinity for both MT1 and MT2, in comparison with the parent compound, balanced by the exhibition of good pharmacokinetic properties.	Nitrogen	29-37	metallothionein 1I, pseudogene	Homo sapiens	95-98
12062797-7	2002	A second focus of the review is the nitrogen regulation of the general amino acid permease, Gap1p, and the proline permease, Put4p, by ubiquitin mediated intracellular protein sorting in the secretory and endosomal pathways.	Nitrogen	36-44	proline permease PUT4	Saccharomyces cerevisiae S288C	125-130
32004937-6	2020	However, the presence of two nitrogen atoms resulted in compounds with lower affinity for both MT1 and MT2, in comparison with the parent compound, balanced by the exhibition of good pharmacokinetic properties.	Nitrogen	29-37	metallothionein 2A	Homo sapiens	103-106
31863323-3	2020	Fragmin, a member in the slime mold Physarum polycephalum, consists of three domains (F1-F3) that are highly similar to the N-terminal half of mammalian gelsolin (G1-G3).	Nitrogen	124-125	gelsolin	Homo sapiens	153-161
31666375-4	2020	Here, we report that vIRF-2 also targets USP7, utilizing a PSTS motif matching the USP7 N-terminal domain-binding A/PxxS consensus, but uniquely requires catalytic-domain residues for intracellular interaction.	Nitrogen	88-89	vIRF-2	Human gammaherpesvirus 8	21-27
11821428-0	2002	Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.	Nitrogen	84-85	porcupine	Drosophila melanogaster	41-50
31802081-1	2020	Formazans (Ar1-NH-N[double bond, length as m-dash]CR3-N[double bond, length as m-dash]N-Ar5), a class of nitrogen-rich and highly colored compounds, have been known since the late 1800s and studied more closely since the early 1940s.	Nitrogen	15-16	transcription factor 20	Homo sapiens	11-14
31802081-1	2020	Formazans (Ar1-NH-N[double bond, length as m-dash]CR3-N[double bond, length as m-dash]N-Ar5), a class of nitrogen-rich and highly colored compounds, have been known since the late 1800s and studied more closely since the early 1940s.	Nitrogen	18-19	transcription factor 20	Homo sapiens	11-14
31802081-1	2020	Formazans (Ar1-NH-N[double bond, length as m-dash]CR3-N[double bond, length as m-dash]N-Ar5), a class of nitrogen-rich and highly colored compounds, have been known since the late 1800s and studied more closely since the early 1940s.	Nitrogen	105-113	transcription factor 20	Homo sapiens	11-14
31706164-3	2020	Functional analysis of the genotype-associated differences in amino acid sequence and the reciprocal mutation experiments in transient-transfection and infection cell models revealed that HBx with asparagine (N) and glutamic acid (E) at 118-119 positions inhibited RIG-I signaling and interacted with MAVS more efficiently than that with lysine (K) and aspartic acid (D).	Nitrogen	209-210	X protein	Hepatitis B virus	188-191
31654721-2	2020	Previous studies have reported that PML-RARalpha is cleaved by neutrophil elastase (NE), an early myeloid-specific serine protease, leading to translocation of the nuclear localization signal (NLS) of the PML protein to the N-terminal of RARalpha.	Nitrogen	84-85	PML nuclear body scaffold	Homo sapiens	36-39
31654721-2	2020	Previous studies have reported that PML-RARalpha is cleaved by neutrophil elastase (NE), an early myeloid-specific serine protease, leading to translocation of the nuclear localization signal (NLS) of the PML protein to the N-terminal of RARalpha.	Nitrogen	84-85	retinoic acid receptor alpha	Homo sapiens	40-48
31654721-2	2020	Previous studies have reported that PML-RARalpha is cleaved by neutrophil elastase (NE), an early myeloid-specific serine protease, leading to translocation of the nuclear localization signal (NLS) of the PML protein to the N-terminal of RARalpha.	Nitrogen	84-85	PML nuclear body scaffold	Homo sapiens	205-208
31654721-2	2020	Previous studies have reported that PML-RARalpha is cleaved by neutrophil elastase (NE), an early myeloid-specific serine protease, leading to translocation of the nuclear localization signal (NLS) of the PML protein to the N-terminal of RARalpha.	Nitrogen	84-85	retinoic acid receptor alpha	Homo sapiens	238-246
31990680-7	2020	Hyperammonemia and use of nitrogen-scavenging agents, two markers of disease severity, were significantly (p&lt;0.001; p=0.001) associated with elevated ALT in ASLD.	Nitrogen	26-34	glutamic pyruvic transaminase, soluble	Mus musculus	153-156
32043503-1	2020	Huntington"s disease (HD) is a genetic neurodegenerative disorder caused by a highly polymorphic CAG trinucleotide repeat expansion encoding an extended polyglutamine (polyQ) tract at the N-terminus of huntingtin protein (HTT).	Nitrogen	188-189	huntingtin	Mus musculus	202-212
31877357-7	2020	Meanwhile, administration of the iNOS inhibitor (1400W) or ONOO- scavenger (Fe-TMPyP), diminished reactive nitrogen species (RNS), remarkably reduced hepatocytes ferroptosis and attenuated ConA-induced liver damage.	Nitrogen	107-115	inositol-3-phosphate synthase 1	Homo sapiens	33-37
32070329-16	2020	CONCLUSIONS: IPF-HLF paracrine signaling leads to IL-6R overexpression, which in turn, affects N-HLF survival.	Nitrogen	2-3	HLF transcription factor, PAR bZIP family member	Homo sapiens	17-20
31785816-4	2020	AGAP1 binds to C-terminus of FilGAP whereas FilGAP binds to N-terminus of AGAP1 containing GLD domain.	Nitrogen	60-61	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	Homo sapiens	74-79
11821428-2	2002	In the absence of Drosophila segment polarity gene porcupine (porc), which encodes an endoplasmic reticulum (ER) multispanning transmembrane protein, the N-glycosylation of Wingless (Wg), one of Drosophila Wnt family, is impaired.	Nitrogen	154-155	porcupine	Drosophila melanogaster	51-60
31793427-4	2020	Since then, 17 Hsp90 inhibitors that target the chaperone"s N-terminal domain, have entered clinical trials.	Nitrogen	60-61	heat shock protein 90 alpha family class A member 1	Homo sapiens	15-20
11821428-2	2002	In the absence of Drosophila segment polarity gene porcupine (porc), which encodes an endoplasmic reticulum (ER) multispanning transmembrane protein, the N-glycosylation of Wingless (Wg), one of Drosophila Wnt family, is impaired.	Nitrogen	154-155	Wnt oncogene analog 2	Drosophila melanogaster	206-209
31793427-6	2020	In these trials, a major limitation observed with Hsp90 inhibition at the N-terminal domain was dose-limiting toxicities and relatively poor pharmacokinetic profiles.	Nitrogen	74-75	heat shock protein 90 alpha family class A member 1	Homo sapiens	50-55
11821428-3	2002	In contrast, the ectopic expression of porc stimulates the N-glycosylation of both endogenously and exogenously expressed Wg.	Nitrogen	59-60	porcupine	Drosophila melanogaster	39-43
31555812-6	2020	The various N-terminal tags, GFP-related Ruby and FLAG, rendered the export CRM1-dependent and especially FLAG-tag caused nuclear accumulation of STAT3, indicating the presence of conformational changes in inactivation.	Nitrogen	12-13	exportin 1	Homo sapiens	76-80
11821428-6	2002	Porc binds the N-terminal 24-amino acid domain (residues 83-106) of Wg, which is highly conserved in the Wnt family and stimulates the N-glycosylation at surrounding sites.	Nitrogen	15-16	porcupine	Drosophila melanogaster	0-4
31622539-7	2020	All these results indicate that the decrease of alpha2,6 sialylation of N-glycans favors the differentiation of most cells and provokes a significant loss of reserve cells.	Nitrogen	72-73	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6	Mus musculus	48-56
11821428-6	2002	Porc binds the N-terminal 24-amino acid domain (residues 83-106) of Wg, which is highly conserved in the Wnt family and stimulates the N-glycosylation at surrounding sites.	Nitrogen	15-16	Wnt oncogene analog 2	Drosophila melanogaster	105-108
11821428-8	2002	Thus, Porc binds the N-terminal specific domain of the Wnt family and stimulates its posttranslational N-glycosylation by anchoring them at the ER membrane possibly through acylation.	Nitrogen	21-22	porcupine	Drosophila melanogaster	6-10
31676442-3	2020	Recent studies indicate that intestinal lipolysis by PNLIP is reduced by Angiopoietin-like protein 4 (ANGPTL4), whose N-terminal domain (nANGPTL4) is a known inactivator of lipoprotein lipase (LPL) in blood circulation and adipocytes.	Nitrogen	54-55	angiopoietin like 4	Homo sapiens	73-100
11821428-8	2002	Thus, Porc binds the N-terminal specific domain of the Wnt family and stimulates its posttranslational N-glycosylation by anchoring them at the ER membrane possibly through acylation.	Nitrogen	21-22	Wnt oncogene analog 2	Drosophila melanogaster	55-58
31676442-3	2020	Recent studies indicate that intestinal lipolysis by PNLIP is reduced by Angiopoietin-like protein 4 (ANGPTL4), whose N-terminal domain (nANGPTL4) is a known inactivator of lipoprotein lipase (LPL) in blood circulation and adipocytes.	Nitrogen	54-55	angiopoietin like 4	Homo sapiens	102-109
31676442-3	2020	Recent studies indicate that intestinal lipolysis by PNLIP is reduced by Angiopoietin-like protein 4 (ANGPTL4), whose N-terminal domain (nANGPTL4) is a known inactivator of lipoprotein lipase (LPL) in blood circulation and adipocytes.	Nitrogen	54-55	lipoprotein lipase	Homo sapiens	173-191
31868291-8	2020	RESULTS: GLM analysis showed that maximum Cho/NAA and Cho/Cr in the tVOI were significantly (P &lt; .05) higher in IDH mutant lesions as compared to wild-type.	Nitrogen	46-49	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	115-118
11805097-8	2002	Glycosylation occurs at a single N-linked site as demonstrated by altered electrophoretic migration of punctin expressed in the presence of tunicamycin A.	Nitrogen	33-34	ADAMTS like 1	Homo sapiens	103-110
31631405-6	2020	GST pull down and yeast two-hybrid assay showed that the interactive smallest fragments were on the 319-379 position of Runx2 and the N-terminus 110-amino acid DBD of the VDR.	Nitrogen	134-135	runt related transcription factor 2	Mus musculus	120-125
31676442-3	2020	Recent studies indicate that intestinal lipolysis by PNLIP is reduced by Angiopoietin-like protein 4 (ANGPTL4), whose N-terminal domain (nANGPTL4) is a known inactivator of lipoprotein lipase (LPL) in blood circulation and adipocytes.	Nitrogen	54-55	lipoprotein lipase	Homo sapiens	193-196
31744379-5	2020	In parallel, ER-residing molecular chaperones, such as HSPA5/GRP78/BiP, are relocated to the cytosol and conjugated with the amino acid L-arginine (Arg) at the N-termini by ATE1 (arginyltransferase 1).	Nitrogen	160-161	arginyltransferase 1	Homo sapiens	173-177
31744379-5	2020	In parallel, ER-residing molecular chaperones, such as HSPA5/GRP78/BiP, are relocated to the cytosol and conjugated with the amino acid L-arginine (Arg) at the N-termini by ATE1 (arginyltransferase 1).	Nitrogen	160-161	arginyltransferase 1	Homo sapiens	179-199
31744379-6	2020	The resulting N-terminal Arg (Nt-Arg) binds the ZZ domain of SQSTM1, inducing oligomerization of SQSTM1-TRIM13 complexes and facilitating recruitment of LC3 on phagophores to the sites of reticulophagy.	Nitrogen	14-15	tripartite motif containing 13	Homo sapiens	104-110
31751593-7	2020	The N-terminal MORN domain of SET7/9 is essential for its interaction with eL42.	Nitrogen	4-5	SET domain containing 7, histone lysine methyltransferase	Homo sapiens	30-36
31756432-5	2020	We demonstrated that untying of the 52 knot in UCHL1 via N-terminal truncation (UCHL1Delta11) significantly reduces its mechanostability.	Nitrogen	57-58	ubiquitin C-terminal hydrolase L1	Homo sapiens	47-52
31604595-6	2020	The nitrogen scavengers, such as NaPB can excrete the waste nitrogen not through the urea cycle but via the alternative pathway.	Nitrogen	4-12	NSF attachment protein beta	Homo sapiens	33-37
31734922-1	2020	In the jasmonate signaling pathway, a region of 17 amino acids within the Jas motif of JAZ proteins and a conserved region within the N-terminus of MYC proteins are sufficient for JAZ-MYC interactions.	Nitrogen	134-135	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	148-151
31734922-1	2020	In the jasmonate signaling pathway, a region of 17 amino acids within the Jas motif of JAZ proteins and a conserved region within the N-terminus of MYC proteins are sufficient for JAZ-MYC interactions.	Nitrogen	134-135	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	184-187
31734922-3	2020	Here, we describe methods of cloning, expression, and purification of MYC N-terminal proteins and their co-crystallization with Jas motif peptides.	Nitrogen	74-75	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	70-73
31585272-3	2020	In practical applications, the combustion atmosphere in oxy-fuel boiler is O2/CO2/H2O, which is different from that in the conventional boiler (O2/N2).	Nitrogen	147-149	complement C2	Homo sapiens	78-85
31604595-6	2020	The nitrogen scavengers, such as NaPB can excrete the waste nitrogen not through the urea cycle but via the alternative pathway.	Nitrogen	60-68	NSF attachment protein beta	Homo sapiens	33-37
11937029-6	2002	The Pkc1 pathway does not regulate the TOR proteins: transcriptional changes dependent on inhibition of the TORs occur normally in pkc1Delta and mpk1Delta mutants when starved for nitrogen; pkc1Delta and mpk1Delta mutants die rapidly upon treatment with rapamycin, an inhibitor of the TORs.	Nitrogen	180-188	protein kinase C	Saccharomyces cerevisiae S288C	4-8
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	paxillin	Homo sapiens	162-170
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	LIF interleukin 6 family cytokine	Homo sapiens	92-95
31905841-7	2019	siTNS3 treatment upregulated p16 and p21 levels and downregulated SOX2 expression and focal adhesion kinase, protein kinase B, and c-Jun N-terminal kinase phosphorylation.	Nitrogen	3-4	H3 histone pseudogene 16	Homo sapiens	37-40
31751124-4	2019	Using a combination of state-of-the-art characterization techniques and molecular modeling, we show that the coupling of N,N,N-trimethyl-1-1-adamantammonium and 1,2-hexanediol, each yielding distinct zeolites when used alone, results in the cooperative direction of a third structure, HOU-4 with the mordenite framework type (MOR).	Nitrogen	121-156	opioid receptor mu 1	Homo sapiens	326-329
11937029-8	2002	Finally, we find that rapamycin treatment or nitrogen starvation induces resistance to the cell wall-digesting enzyme zymolyase by a Pkc1-dependent mechanism.	Nitrogen	45-53	protein kinase C	Saccharomyces cerevisiae S288C	133-137
31715395-1	2020	To efficiently and selectively produce liquid hydrocarbon fuels, e.g., methanol, by CO2 photoelectrochemical reduction, CdS nanoparticles (NPs) anchored on the nitrogen-doped carbon particles (NCP) with core-shell dodecahedral porous structure were used as cathode catalysts.	Nitrogen	160-168	CDP-diacylglycerol synthase 1	Homo sapiens	120-123
11953450-2	2002	Since amphoterin is a ligand for the receptor for advanced glycation end products (RAGE), and the ligand-binding V-domain of the receptor contains two potential N -glycosylation sites, we hypothesized that N -glycans on RAGE may mediate its interactions with amphoterin.	Nitrogen	161-162	high mobility group box 1	Homo sapiens	6-16
31715395-3	2020	The heterojunction generated between CdS with abundant S-vacancies and NCP with a high content of pyridinic N acted as synergistic catalyst for CO2 reduction.	Nitrogen	98-109	CDP-diacylglycerol synthase 1	Homo sapiens	37-40
32005855-7	2020	PTPdelta D2 interacts with the N-terminal helix and the first and second SAMs (SAM1 and SAM2, respectively) of Liprin-alpha3.	Nitrogen	31-32	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3	Mus musculus	111-124
31791120-3	2019	By activation with potassium hydroxide, this cobalt system shows both high efficiency (up to 24000 TON and 12000 h-1 TOF) and excellent chemoselectivities with various aldehydes, ketones, imines and even N-heteroarenes.	Nitrogen	204-218	FEZ family zinc finger 2	Homo sapiens	117-120
31878192-1	2019	Rpb11 subunit of RNA polymerase II of Eukaryotes is related to N-terminal domain of eubacterial alpha subunit and forms a complex with Rpb3 subunit analogous to prokaryotic alpha2 homodimer, which is involved in RNA polymerase assembly and promoter recognition.	Nitrogen	18-19	RNA polymerase II subunit C	Homo sapiens	135-139
11792566-1	2002	Nitrogen-containing bisphosphonates (NBps) are taken up by osteoclasts and inhibit farnesyl pyrophosphate synthase, an enzyme of the mevalonate pathway.	Nitrogen	0-8	farnesyl diphosphate synthetase	Mus musculus	83-114
31599159-6	2019	Af1521 and ARH3 crystal structures with bound ADP-ribose revealed similar ADP-ribose-binding pockets with the catalytic residues of the ARH and macrodomain protein families in the N-terminal helix and loop.	Nitrogen	180-181	ADP-ribosylserine hydrolase	Homo sapiens	11-15
31895395-2	2020	In this study, we successfully prepared cobalt phosphide and cobalt nanoparticles embedded into nitrogen-doped nanoporous carbon (CoP-CoNC/CC) using a simple precipitation method followed by pyrolysis-phosphatization.	Nitrogen	96-104	caspase recruitment domain family member 16	Homo sapiens	130-133
31987044-11	2020	This was linked to an XBP1-dependent activation of c-Jun N-terminal kinase, which was pro-apoptotic in LNCaP but not HCT116 cells.	Nitrogen	57-58	X-box binding protein 1	Homo sapiens	22-26
11732900-2	2001	A basic nitrogen was introduced into a general PTP inhibitor to form a salt bridge to Asp48 in PTP1B and simultaneously cause repulsion in PTPs containing an asparagine in the equivalent position [Iversen, L. F., et al.	Nitrogen	8-16	protein tyrosine phosphatase receptor type U	Homo sapiens	47-50
31870146-8	2020	We also propose a ligand induced conformational change bringing the N-termini of RAR and RXR closer together.	Nitrogen	68-69	retinoic acid receptor alpha	Homo sapiens	81-84
31877778-0	2019	N-Terminal Truncated Myb with New Transcriptional Activity Produced Through Use of an Alternative MYB Promoter in Salivary Gland Adenoid Cystic Carcinoma.	Nitrogen	0-1	MYB proto-oncogene, transcription factor	Homo sapiens	21-24
31877778-0	2019	N-Terminal Truncated Myb with New Transcriptional Activity Produced Through Use of an Alternative MYB Promoter in Salivary Gland Adenoid Cystic Carcinoma.	Nitrogen	0-1	MYB proto-oncogene, transcription factor	Homo sapiens	98-101
31877778-3	2019	The alternative promoter transcripts produce N-terminally truncated Myb proteins lacking a highly conserved and phosphorylated domain, which includes the pS11 epitope that is frequently used to detect Myb proteins.	Nitrogen	45-46	MYB proto-oncogene, transcription factor	Homo sapiens	68-71
31877778-4	2019	In RNA-seq assays, Myb isoforms lacking the N-terminal domain displayed unique transcriptional activities, regulating many genes differently than full-length Myb.	Nitrogen	4-5	MYB proto-oncogene, transcription factor	Homo sapiens	19-22
31634510-3	2019	In this study, chimeric VLP were investigated displaying the 195 N-terminal amino acids derived from the glycoprotein E2 of the bovine viral diarrhea virus (BVDV) on their surface.	Nitrogen	65-66	VHL like	Homo sapiens	24-27
31634510-4	2019	Isolation of the VLP from methylotrophic yeast Hansenula polymorpha was allowed upon co-expression of wild-type dS and a fusion protein composed of the BVDV-derived antigen N-terminally fused to the dS.	Nitrogen	173-174	VHL like	Homo sapiens	17-20
31734159-5	2019	Transcriptomic analyses revealed that isobutanol induces a nitrogen starvation response via GLN3 and GCN4, upregulating amino acid biosynthesis and nitrogen scavenging while downregulating glycolysis, cell wall biogenesis, and membrane lipid biosynthesis.	Nitrogen	59-67	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	92-96
31734159-5	2019	Transcriptomic analyses revealed that isobutanol induces a nitrogen starvation response via GLN3 and GCN4, upregulating amino acid biosynthesis and nitrogen scavenging while downregulating glycolysis, cell wall biogenesis, and membrane lipid biosynthesis.	Nitrogen	148-156	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	92-96
31714482-9	2019	In addition, N15 treatment markedly increased the newly mature neurons and enhanced the expression levels of growth-associated protein-43, synaptophysin, brain-derived neurotrophic factor and neurotrophin-3 in the hippocampus.	Nitrogen	13-16	neurotrophin 3	Rattus norvegicus	192-206
31714482-10	2019	Moreover, N15 promoted the activation of PPARalpha and PPARgamma on day 7 and 14 after cerebral ischaemia.	Nitrogen	10-13	peroxisome proliferator activated receptor alpha	Rattus norvegicus	41-50
31714482-11	2019	These results reveal that N15 may promote neurogenesis and neuroplasticity in MCAO rats through the activation of the PPARalpha/gamma dual signal pathway.	Nitrogen	26-29	peroxisome proliferator activated receptor alpha	Rattus norvegicus	118-127
11732900-2	2001	A basic nitrogen was introduced into a general PTP inhibitor to form a salt bridge to Asp48 in PTP1B and simultaneously cause repulsion in PTPs containing an asparagine in the equivalent position [Iversen, L. F., et al.	Nitrogen	8-16	6-pyruvoyltetrahydropterin synthase	Homo sapiens	139-143
11728190-8	2001	Evaluation of these compounds for displacing [3H]WIN 35 428 binding at DAT in rat caudate putamen revealed that the 4"-azido-3"-iodophenylbutyl substituent, found in 1, provided optimal binding affinity and was chosen to replace the N-CH3 group on 2.	Nitrogen	51-52	solute carrier family 6 member 3	Rattus norvegicus	71-74
31776255-4	2019	In elongation factor G (EF-G), a highly conserved protein composed of 5 domains, the 2 N-terminal domains form a stably structured unit cotranslationally.	Nitrogen	87-88	G elongation factor mitochondrial 1	Homo sapiens	3-22
31776255-4	2019	In elongation factor G (EF-G), a highly conserved protein composed of 5 domains, the 2 N-terminal domains form a stably structured unit cotranslationally.	Nitrogen	87-88	G elongation factor mitochondrial 1	Homo sapiens	24-28
11706193-3	2001	In a homozygous line, the PPDK protein accounted for 35% of total leaf-soluble protein or 16% of total leaf nitrogen.	Nitrogen	108-116	pyruvate, phosphate dikinase 1, chloroplastic	Zea mays	26-30
31836717-4	2019	The distal and proximal ubiquitin moieties of Lys48-linked diubiquitin primarily interact with the C-terminal helix and N-terminal loop of the Npl4 C-terminal domain (CTD), respectively.	Nitrogen	120-121	nuclear protein localization protein 4	Saccharomyces cerevisiae S288C	143-147
31836717-6	2019	Ufd1 occupies a hydrophobic groove of the Mpr1/Pad1 N-terminal (MPN) domain of Npl4, which corresponds to the catalytic groove of the MPN domain of JAB1/MPN/Mov34 metalloenzyme (JAMM)-family deubiquitylating enzyme.	Nitrogen	52-53	polyubiquitin-binding protein UFD1	Saccharomyces cerevisiae S288C	0-4
31836717-6	2019	Ufd1 occupies a hydrophobic groove of the Mpr1/Pad1 N-terminal (MPN) domain of Npl4, which corresponds to the catalytic groove of the MPN domain of JAB1/MPN/Mov34 metalloenzyme (JAMM)-family deubiquitylating enzyme.	Nitrogen	52-53	phenylacrylic acid decarboxylase PAD1	Saccharomyces cerevisiae S288C	47-51
31836717-6	2019	Ufd1 occupies a hydrophobic groove of the Mpr1/Pad1 N-terminal (MPN) domain of Npl4, which corresponds to the catalytic groove of the MPN domain of JAB1/MPN/Mov34 metalloenzyme (JAMM)-family deubiquitylating enzyme.	Nitrogen	52-53	nuclear protein localization protein 4	Saccharomyces cerevisiae S288C	79-83
11559807-3	2001	Substitution of pAPN amino acids 283 to 290 into hAPN for the corresponding amino acids 288 to 295 introduced an N-glycosylation sequon at amino acids 291 to 293 that blocked HCoV-229E receptor activity of hAPN.	Nitrogen	19-20	alanyl aminopeptidase, membrane	Homo sapiens	49-53
31836717-6	2019	Ufd1 occupies a hydrophobic groove of the Mpr1/Pad1 N-terminal (MPN) domain of Npl4, which corresponds to the catalytic groove of the MPN domain of JAB1/MPN/Mov34 metalloenzyme (JAMM)-family deubiquitylating enzyme.	Nitrogen	52-53	COP9 signalosome catalytic subunit RRI1	Saccharomyces cerevisiae S288C	148-152
31623829-1	2019	BACKGROUND: FUT8-mediated core fucosylation, which transfers a fucose residue from GDP-fucose to core-GlcNAc of the N-linked type glycoproteins, is crucial for signaling receptors function.	Nitrogen	8-9	fucosyltransferase 8	Mus musculus	12-16
11559807-4	2001	Substitution of two amino acids that inserted an N-glycosylation site at amino acid 291 also resulted in a mutant hAPN that lacked receptor activity because it failed to bind HCoV-229E.	Nitrogen	49-50	alanyl aminopeptidase, membrane	Homo sapiens	114-118
11598210-4	2001	Gpi16p is an essential N-glycosylated transmembrane glycoprotein.	Nitrogen	23-24	GPI-anchor transamidase subunit GPI16	Saccharomyces cerevisiae S288C	0-6
31677073-8	2019	Moreover, the "C=C" on the seven-membered ring and "C=O" on the nitrogen of CBZ may be contribute to NLRP3 inflammasome hyperactivation and hepatotoxicity.	Nitrogen	64-72	NLR family, pyrin domain containing 3	Mus musculus	101-106
31533545-5	2019	Results: Inhibition of FLT3 mutant cells by drugs reported in recent literatures involves the influence of glycosylation of FLT3: 2-deoxy-D-glucose, Tunicamycin and Fluvastatin are reported to inhibit N-glycosylation of FLT3; Pim-1 inhibitors are proved to block the inhibition of Pim-1 on FLT3 Oglycosylation; HSP90 inhibitors and Tyrosine Kinase Inhibitors are shown to increase fully glycosylated form of FLT3.	Nitrogen	201-202	heat shock protein 90 alpha family class A member 1	Homo sapiens	311-316
31573043-13	2019	The level of red fluorescence was observed prior to and following the administration of G418 using antibodies targeting the N- or C-terminus of the HERG protein.	Nitrogen	124-125	potassium voltage-gated channel subfamily H member 2	Homo sapiens	148-152
31550533-2	2019	Driven by an N-terminal alpha/beta-hydrolase-folded domain with a protruding interaction helix, EDS1 assembles with two homologs, phytoalexin-deficient 4 (PAD4) and senescence-associated gene 101 (SAG101).	Nitrogen	13-14	senescence-associated gene 101	Arabidopsis thaliana	165-195
31788114-5	2019	Further experiments demonstrated that miR-221-5p expression was downregulated in N-MSCs following osteoblast induction while no obvious alterations in expression levels were observed in MBD-MSCs.	Nitrogen	81-82	microRNA 221	Homo sapiens	38-45
31828091-6	2019	WBP5 expression was significantly correlated with bilaterality, capsule invasion, and N-stage, and it was a favorable factor of DFS.	Nitrogen	86-87	transcription elongation factor A like 9	Homo sapiens	0-4
31699039-9	2019	Further molecular modeling, docking and simulation approaches revealed significant conformational changes in the N-terminus region of normal to mutant CTNNB1 gene critical for binding with Glycogen synthase kinase 3-B (GSK3) and transducin containing protein1 (TrCp1).	Nitrogen	113-114	catenin beta 1	Homo sapiens	151-157
31650881-9	2019	Mechanistically, TRAF1 promotes myocardial I/R injury through regulating ASK1 (apoptosis signal-regulating kinase 1)-mediated JNK/p38 (c-Jun N-terminal kinase/p38) MAPK (mitogen-activated protein kinase) cascades.	Nitrogen	127-128	TNF receptor-associated factor 1	Mus musculus	17-22
31650881-9	2019	Mechanistically, TRAF1 promotes myocardial I/R injury through regulating ASK1 (apoptosis signal-regulating kinase 1)-mediated JNK/p38 (c-Jun N-terminal kinase/p38) MAPK (mitogen-activated protein kinase) cascades.	Nitrogen	127-128	mitogen-activated protein kinase kinase kinase 5	Mus musculus	73-77
31650881-9	2019	Mechanistically, TRAF1 promotes myocardial I/R injury through regulating ASK1 (apoptosis signal-regulating kinase 1)-mediated JNK/p38 (c-Jun N-terminal kinase/p38) MAPK (mitogen-activated protein kinase) cascades.	Nitrogen	127-128	mitogen-activated protein kinase kinase kinase 5	Mus musculus	79-115
31404731-6	2019	The preferential adsorptions of Pb2+ &gt; Cu2+ &gt; Cd2+ were likely due to the different affinities of the metals to the lone pair of electrons on the N atom from the amide groups and/or the O atoms from the -OH and -COO- groups on C-AL.	Nitrogen	152-153	CD2 molecule	Homo sapiens	52-55
31441965-1	2019	The covalent nature of strong N-Br   N halogen bonds in a cocrystal (2) of N-bromosuccinimide (NBS) with 3,5-dimethylpyridine (lut) was determined from X-ray charge density studies and compared to a weak N-Br   O halogen bond in pure crystalline NBS (1) and a covalent bond in bis(3-methylpyridine)bromonium cation (in its perchlorate salt (3).	Nitrogen	30-31	nibrin	Homo sapiens	95-98
31441965-1	2019	The covalent nature of strong N-Br   N halogen bonds in a cocrystal (2) of N-bromosuccinimide (NBS) with 3,5-dimethylpyridine (lut) was determined from X-ray charge density studies and compared to a weak N-Br   O halogen bond in pure crystalline NBS (1) and a covalent bond in bis(3-methylpyridine)bromonium cation (in its perchlorate salt (3).	Nitrogen	30-31	nibrin	Homo sapiens	246-249
31586028-3	2019	4 lysine residues (K38KKK) located in the N-terminal domain of caspase-7 form such an exosite and promote the rapid proteolysis of the poly(ADP-ribose) polymerase 1 (PARP-1), but the mechanism of recognition remains mostly unknown.	Nitrogen	42-43	caspase 7	Homo sapiens	63-72
31680899-3	2019	We suggest that this N-terminal extension might confer male-specific roles on FruM interaction partner proteins such as Lola, which otherwise operates as a transcription factor common to both sexes.	Nitrogen	21-22	longitudinals lacking	Drosophila melanogaster	120-124
31550138-4	2019	Here we report the first X-ray crystal structure of a reactive Rh2 nitrenoid, enabled by N2 elimination from an organic azide ligand within a single-crystal matrix.	Nitrogen	89-91	Rh associated glycoprotein	Homo sapiens	63-66
31681742-9	2019	The effect of amino acid supplementation of the medium was investigated and the nitrogen metabolism of S. cerevisiae was altered by knock-out of TOR1 or YIH1.	Nitrogen	80-88	Yih1p	Saccharomyces cerevisiae S288C	153-157
31632077-10	2019	The SOX17 N-terminus was proved to be necessary for these effects.	Nitrogen	10-11	SRY-box transcription factor 17	Homo sapiens	4-9
31589148-7	2019	The other two oxadiazole N atoms coordinate to the two Ag2 centres of the Ag2(O2CCF3)4 dimer.	Nitrogen	25-26	anterior gradient 2, protein disulphide isomerase family member	Homo sapiens	55-58
31589148-7	2019	The other two oxadiazole N atoms coordinate to the two Ag2 centres of the Ag2(O2CCF3)4 dimer.	Nitrogen	25-26	anterior gradient 2, protein disulphide isomerase family member	Homo sapiens	74-77
31667130-7	2019	It was confirmed that APPB inhibits N-glycosylation of beta-catenin at 2.5 nM concentration.	Nitrogen	36-37	catenin beta 1	Rattus norvegicus	55-67
31549143-9	2019	Moreover, NCG enhanced plasma NO level; upregulated expression of PKG-I, Raf1, and p-p38; and increased angiogenesis of the ovaries.	Nitrogen	10-13	Raf-1 proto-oncogene, serine/threonine kinase	Gallus gallus	73-77
31313891-7	2019	NbS, CrS, TiS, and VS are also promising candidates for both the associative and dissociative mechanisms with overpotentials for nitrogen reduction around 0.7-1.1 V.	Nitrogen	129-137	nibrin	Homo sapiens	0-3
31543703-0	2019	The Short N-Terminal Repeats of Transcription Termination Factor 1 Contain Semi-Redundant Nucleolar Localization Signals and P19-ARF Tumor Suppressor Binding Sites.	Nitrogen	10-11	transcription termination factor, RNA polymerase I	Mus musculus	32-66
31543703-7	2019	We find that both sequences lie within the 25 amino acid N-terminal repeats of TTF1.	Nitrogen	57-58	transcription termination factor, RNA polymerase I	Mus musculus	79-83
31543703-10	2019	The data suggest that the N-terminal repeats of mouse TTF1, and by analogy those of human TTF1, cooperate to mediate both nucleolar localization and ARF binding.	Nitrogen	26-27	transcription termination factor, RNA polymerase I	Mus musculus	54-58
31454245-1	2019	A comprehensive DFT study of the electrocatalytic oxidation of ammonia to dinitrogen by a ruthenium polypyridyl complex, [(tpy)(bpy)RuII(NH3)]2+ (a), and its NMe2-substituted derivative (b) is presented.	Nitrogen	74-84	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	158-162
31620127-4	2019	Since the antiviral roles of DDX23 have not been characterized in mammals, we performed further poly(I:C) pull-down assays and found that human DDX23 binds to LMW poly(I:C) through its N-terminal region, suggesting that DDX23 is an evolutionarily conserved dsRNA sensor.	Nitrogen	185-186	DEAD-box helicase 23	Homo sapiens	144-149
31620127-4	2019	Since the antiviral roles of DDX23 have not been characterized in mammals, we performed further poly(I:C) pull-down assays and found that human DDX23 binds to LMW poly(I:C) through its N-terminal region, suggesting that DDX23 is an evolutionarily conserved dsRNA sensor.	Nitrogen	185-186	DEAD-box helicase 23	Homo sapiens	144-149
31521187-4	2019	RESULTS: We found that hyl1 mutant plants are more sensitive to tunicamycin, an inhibitor of N-linked glycosylation that causes ER stress than wild-type plants.	Nitrogen	93-94	dsRNA-binding domain-like superfamily protein	Arabidopsis thaliana	23-27
31500265-3	2019	Molecular complexes between glycolic acid and nitrogen were studied in a low-temperature argon matrix with FTIR spectroscopy, and supported by MP2 and BLYPD3 calculations.	Nitrogen	46-54	tryptase pseudogene 1	Homo sapiens	143-146
31297960-4	2019	FAM20C is a ubiquitously expressed protein kinase that contains five functional domains including a catalytic domain, a binding pocket for FAM20A and three distinct N-glycosylation sites.	Nitrogen	165-166	FAM20C golgi associated secretory pathway kinase	Homo sapiens	0-6
31297960-8	2019	Following in silico analysis and mapping of the variant on a three-dimensional (3D) model of FAM20C it is predicted to be deleterious and to affect N-glycosylation, protein folding, and subsequent secretion of FAM20C.	Nitrogen	148-149	FAM20C golgi associated secretory pathway kinase	Homo sapiens	93-99
31297960-8	2019	Following in silico analysis and mapping of the variant on a three-dimensional (3D) model of FAM20C it is predicted to be deleterious and to affect N-glycosylation, protein folding, and subsequent secretion of FAM20C.	Nitrogen	148-149	FAM20C golgi associated secretory pathway kinase	Homo sapiens	210-216
30931530-6	2019	Recently, defective N-glycosylation of betaDG has been reported in patients with mutations in guanosine-diphosphate-mannose pyrophosphorylase B (GMPPB).	Nitrogen	20-21	GDP-mannose pyrophosphorylase B	Homo sapiens	94-143
30931530-6	2019	Recently, defective N-glycosylation of betaDG has been reported in patients with mutations in guanosine-diphosphate-mannose pyrophosphorylase B (GMPPB).	Nitrogen	20-21	GDP-mannose pyrophosphorylase B	Homo sapiens	145-150
30077416-4	2019	In contrast to tapasin, TAPBPR bound strongly to MHC class I molecules that lacked N-linked glycosylation, suggesting that the TAPBPR:MHC class I interaction is glycan independent.	Nitrogen	83-84	TAP binding protein like	Homo sapiens	24-30
31673305-1	2019	X-linked inhibitor of apoptosis protein (XIAP) is an important regulator of cancer cell survival whose BIR3 domain (XIAP-BIR3) recognizes the Smac N-terminal tetrapeptide sequence (AVPI), making it an attractive protein-protein interaction (PPI) target for cancer therapies.	Nitrogen	147-148	diablo IAP-binding mitochondrial protein	Homo sapiens	142-146
31963721-10	2020	As a consequence, the free thiol of monomeric Tff1 could have a protective scavenger function, e.g., for reactive oxygen/nitrogen species.	Nitrogen	121-129	trefoil factor 1	Mus musculus	46-50
31934853-5	2020	The module at the N-terminus of Notch ligand (MNNL) of Dll4 is inherently advantageous over Dll1.	Nitrogen	18-19	delta like canonical Notch ligand 1	Mus musculus	92-96
32064376-3	2020	These isoforms carry minor variations in the flanking region of the N-terminal actin-binding domain (ABD1) of dystrophin, which is composed of two calponin-homology (CH) domains in tandem.	Nitrogen	68-69	dystrophin	Homo sapiens	110-120
32064376-5	2020	We studied the impact of differences in the N-terminal flanking region on the structure and function of dystrophin tandem CH domain isoforms.	Nitrogen	44-45	dystrophin	Homo sapiens	104-114
32064376-9	2020	In conclusion, tandem CH domain isoforms might be using minor sequence variations in the N-terminal flanking regions to modulate their thermodynamic stability and actin-binding function, thus leading to specificity in dystrophin-actin interactions in various tissues.	Nitrogen	89-90	dystrophin	Homo sapiens	218-228
31633754-2	2020	CD90+ (myo-)fibroblasts (MFs) are abundant cells in the normal (N) intestinal mucosa contributing to mucosal tolerance via suppression of Th1 cell activity through cell surface membrane-bound PD-L1 (mPD-L1).	Nitrogen	64-65	Thy-1 cell surface antigen	Homo sapiens	0-4
31633754-6	2020	Herein we observed that when compared to N- and ulcerative colitis (UC)-MFs, CD-MFs increase in LPS-inducible levels of MMP-7 and -9 with a significant increase in both basal and inducible MMP-10.	Nitrogen	41-42	matrix metallopeptidase 7	Homo sapiens	120-132
31633754-8	2020	Treatment of N-MFs with a combination of recombinant human MMP-7, -9 and -10 significantly decreased mPD-L1.	Nitrogen	13-14	matrix metallopeptidase 7	Homo sapiens	59-76
31969820-3	2019	CRF2 encompasses three spliced variants in humans, alpha (CRF2alpha), beta (CRF2beta), and gamma (CRF2gamma), which differ in their N-terminal extracellular domains and expression patterns.	Nitrogen	132-133	corticotropin releasing hormone receptor 2	Homo sapiens	0-4
31922001-4	2020	To this end, we used N-induced lattice contraction to generally boost the HER catalysis of P-rich TMPs including CoP2, FeP2, NiP2, and MoP2.	Nitrogen	21-22	BCL2 interacting protein 2	Homo sapiens	125-129
31922001-4	2020	To this end, we used N-induced lattice contraction to generally boost the HER catalysis of P-rich TMPs including CoP2, FeP2, NiP2, and MoP2.	Nitrogen	21-22	endothelial PAS domain protein 1	Homo sapiens	135-139
31706164-4	2020	An impaired RIG-I-induced MAVS aggregation was observed in the presence of HBx-118N119E while MAVS-TRAF3 interaction was not affected.	Nitrogen	82-83	mitochondrial antiviral signaling protein	Homo sapiens	26-30
31706164-4	2020	An impaired RIG-I-induced MAVS aggregation was observed in the presence of HBx-118N119E while MAVS-TRAF3 interaction was not affected.	Nitrogen	82-83	X protein	Hepatitis B virus	75-78
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	222-226
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	222-226
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	222-226
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	222-226
32761765-7	2020	The results of this experiment suggest that decreasing dietary CP to 16% (early period) or 12% (late period) of dry matter would reduce nitrogen excretion from Holstein fattening farms without affecting productivity.	Nitrogen	136-144	ceruloplasmin	Homo sapiens	63-65
32985231-6	2020	Microinjection of N-(1,3,4-Thiadiazolyl)nicotinamide-020 [TGN-020, a specific blocker of aquaporin 4] into the SON blocked MCAO-evoked increases in pERK1/2 in the SON as well as the reduction of GFAP and the increase in pERK1/2 and aquaporin 4 in the infarction area of the cortex.	Nitrogen	18-21	aquaporin 4	Rattus norvegicus	89-100
32985231-6	2020	Microinjection of N-(1,3,4-Thiadiazolyl)nicotinamide-020 [TGN-020, a specific blocker of aquaporin 4] into the SON blocked MCAO-evoked increases in pERK1/2 in the SON as well as the reduction of GFAP and the increase in pERK1/2 and aquaporin 4 in the infarction area of the cortex.	Nitrogen	18-21	aquaporin 4	Rattus norvegicus	232-243
32990603-2	2020	Methionine (Met), the sole essential amino acid bearing a sulfur (S) atom, presides at the initiation of protein synthesis while maintaining stable body tissue S:N molar ratios of approximately 1:14.5.	Nitrogen	162-163	SAFB like transcription modulator	Homo sapiens	0-3
31655022-4	2020	Key Results I/R injury up-regulated renal expression of FOXO1, and treatment with FOXO1-selective inhibitor AS1842856 prior to I/R injury decreased serum urea nitrogen, serum creatinine and the tubular damage score after injury.	Nitrogen	159-167	forkhead box O1	Mus musculus	82-87
31479875-3	2020	We introduced de novo N-glycosylation of IFNlambda4, guided by structural analysis, and produced IFNlambda4 variants in Expi293F that displayed improved expression and potency.	Nitrogen	22-23	interferon lambda 4 (gene/pseudogene)	Homo sapiens	41-51
31479875-3	2020	We introduced de novo N-glycosylation of IFNlambda4, guided by structural analysis, and produced IFNlambda4 variants in Expi293F that displayed improved expression and potency.	Nitrogen	22-23	interferon lambda 4 (gene/pseudogene)	Homo sapiens	97-107
31699808-4	2020	Where cytochrome P450 (P450) was responsible for the metabolism in rats with a low Michaelis constant, human-specific UDP-glucuronosyltransferase 2B10- and 1A4-mediated N-glucuronidation was identified as the leading contributor to metabolism in humans with a high V max capacity.	Nitrogen	169-170	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	118-159
31625834-2	2020	Saccharomyces cerevisiae BAP2 gene encodes the permease responsible for most uptake of leucine, valine and isoleucine, amino acids that this yeast can use as nitrogen sources.	Nitrogen	158-166	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	25-29
31625834-4	2020	In this context, the results presented in this paper show that BAP2 is an inducible gene in the presence of nitrogen-non-preferred source proline but exhibits high constitutive non-inducible expression in nitrogen-preferred source ammonium.	Nitrogen	108-116	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	63-67
31625834-4	2020	In this context, the results presented in this paper show that BAP2 is an inducible gene in the presence of nitrogen-non-preferred source proline but exhibits high constitutive non-inducible expression in nitrogen-preferred source ammonium.	Nitrogen	205-213	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	63-67
33342467-1	2020	Phosphoglucomutase 1 deficiency is a congenital disorder of glycosylation (CDG) with multiorgan involvement affecting carbohydrate metabolism, N-glycosylation and energy production.	Nitrogen	143-144	phosphoglucomutase 1	Homo sapiens	0-20
31802003-4	2020	We find that six highly divergent molecular chaperones commonly recognize a canonical motif in alpha-synuclein, consisting of the N terminus and a segment around Tyr39, and hinder the aggregation of alpha-synuclein.	Nitrogen	130-131	synuclein alpha	Homo sapiens	95-110
31802003-4	2020	We find that six highly divergent molecular chaperones commonly recognize a canonical motif in alpha-synuclein, consisting of the N terminus and a segment around Tyr39, and hinder the aggregation of alpha-synuclein.	Nitrogen	130-131	synuclein alpha	Homo sapiens	199-214
31715212-3	2020	In this study, N-methylated peptide inhibitors F-N(Me)H-L, V-N(Me)F-R and R-N(Me)V-Y were synthesized against ACE, NEP and APN respectively, using their respective physiological substrates.	Nitrogen	15-16	alanyl aminopeptidase, membrane	Rattus norvegicus	123-126
31520495-9	2020	Together, the results demonstrate that the SUT1-overexpressing plants with enhanced sucrose allocation to sinks adjust leaf carbon and nitrogen metabolism, and amino acid partitioning in order to accommodate the increased assimilate demand of growing seeds.	Nitrogen	135-143	solute carrier family 13 member 4	Homo sapiens	43-47
31750645-4	2019	The as-prepared MCNC@COF@GSH microspheres possessed fast magnetic responsiveness, regular porosity, large surface areas, and good hydrophilicity, resulting in remarkable performances in N-linked glycopeptide enrichment with low detection limit (0.01 fmol muL-1), high selectivity (1:5000, human IgG digests to bovine serum albumin digests), excellent size-exclusion effect (IgG digests/IgG/BSA, 1:500:500), and reusability (at least five times).	Nitrogen	18-19	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	255-260
31597781-7	2019	We confirmed a direct specific interaction between APH-2 and HRS and show that the CC2 domain of HRS and the N-terminal domain of APH-2 mediate their interaction.	Nitrogen	109-110	zinc finger DHHC-type palmitoyltransferase 16	Homo sapiens	51-56
31597781-7	2019	We confirmed a direct specific interaction between APH-2 and HRS and show that the CC2 domain of HRS and the N-terminal domain of APH-2 mediate their interaction.	Nitrogen	109-110	zinc finger DHHC-type palmitoyltransferase 16	Homo sapiens	130-135
31605674-6	2019	The findings confirmed that CYP3A4 was a major contributor (at least 30% total metabolism) to all three of the possible N-dealkylation pathways; however, CYP2C9, and not CYP2C19, played a critical role in terbinafine metabolism and even exceeded CYP3A4 contributions for terbinafine N-demethylation.	Nitrogen	120-121	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	154-160
31605674-6	2019	The findings confirmed that CYP3A4 was a major contributor (at least 30% total metabolism) to all three of the possible N-dealkylation pathways; however, CYP2C9, and not CYP2C19, played a critical role in terbinafine metabolism and even exceeded CYP3A4 contributions for terbinafine N-demethylation.	Nitrogen	283-284	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	154-160
32055299-5	2019	In this review, IDO1 inhibitors are grouped as tryptophan derivatives, inhibitors with an imidazole, 1,2,3-triazole or tetrazole scaffold, inhibitors with quinone or iminoquinone, N-hydroxyamidines and other derivatives, and their enzymatic inhibitory activity, selectivity and other biological activities are also introduced and summarized.	Nitrogen	180-197	indoleamine 2,3-dioxygenase 1	Homo sapiens	16-20
31161211-9	2019	CHE concentration was significantly associated with all-cause mortality independently of GNRI, CONUT score, or PNI, after adjustment for major confounders including other nutritional indices, such as age, sex, systolic blood pressure, BMI, left ventricular ejection fraction, history of hypertension, diabetes mellitus, dyslipidemia, prior heart failure hospitalization, angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use, beta-blocker use, statin use, hemoglobin, sodium, blood urea nitrogen, albumin, C-reactive protein, and brain natriuretic peptide concentrations via multivariable Cox analysis.	Nitrogen	509-517	butyrylcholinesterase	Homo sapiens	0-3
11553754-10	2001	These results collectively indicate that AtNrt2.1 and/or AtNrt2.2 genes play a key role in the regulation of the high-affinity NO(3)(-) uptake, and in the adaptative responses of the plant to both spatial and temporal changes in nitrogen availability in the environment.	Nitrogen	229-237	nitrate transporter 2.2	Arabidopsis thaliana	57-65
31675572-9	2019	In addition, it was shown that GAC improved the removal of less oxidized, higher nitrogen content, and higher double bond equivalent (DBE) organic compounds.	Nitrogen	81-89	glutaminase	Homo sapiens	31-34
31638418-1	2019	N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate.	Nitrogen	0-17	N-acetyltransferase 8-like	Mus musculus	42-71
31638418-1	2019	N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate.	Nitrogen	0-17	N-acetyltransferase 8-like	Mus musculus	79-84
31638418-1	2019	N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate.	Nitrogen	19-22	N-acetyltransferase 8-like	Mus musculus	42-71
31638418-1	2019	N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate.	Nitrogen	19-22	N-acetyltransferase 8-like	Mus musculus	79-84
31638418-5	2019	We identified an important role of NAA availability in the brain during adolescence, as 75% of Nat8l-ko mice died on fat-free diet (FFD) after weaning but could be rescued by NAA supplementation.	Nitrogen	35-38	N-acetyltransferase 8-like	Mus musculus	95-100
31638418-5	2019	We identified an important role of NAA availability in the brain during adolescence, as 75% of Nat8l-ko mice died on fat-free diet (FFD) after weaning but could be rescued by NAA supplementation.	Nitrogen	175-178	N-acetyltransferase 8-like	Mus musculus	95-100
11356843-0	2001	Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.	Nitrogen	62-70	glucose-induced degradation complex subunit VID30	Saccharomyces cerevisiae S288C	39-45
31638418-6	2019	In adult life, NAA deficiency promotes a beneficial metabolic phenotype, as Nat8l-ko and Nat8l-ako mice showed reduced body weight, increased energy expenditure, and improved glucose tolerance on chow, high-fat, and FFDs.	Nitrogen	15-18	N-acetyltransferase 8-like	Mus musculus	76-81
31638418-6	2019	In adult life, NAA deficiency promotes a beneficial metabolic phenotype, as Nat8l-ko and Nat8l-ako mice showed reduced body weight, increased energy expenditure, and improved glucose tolerance on chow, high-fat, and FFDs.	Nitrogen	15-18	N-acetyltransferase 8-like	Mus musculus	89-94
32029032-1	2019	OBJECTIVE: To investigate whether endogenous nociceptin/orphanin FQ (N/OFQ) can inhibit arrhythmia and expression of beta1-adrenergic receptor (beta1-AR) on the surface of myocardial cell membrane in acute myocardial ischemia rats by Raf kinase inhibitory protein (RKIP).	Nitrogen	69-70	prepronociceptin	Rattus norvegicus	45-55
11356843-2	2001	When cells are cultured with a good nitrogen source (glutamine, ammonia), Gln3p and Gat1p are restricted to the cytoplasm, whereas with a poor nitrogen source (proline), they localize to the nucleus, bind to the GATA sequences of NCR-sensitive gene promoters, and activate transcription.	Nitrogen	36-44	Gat1p	Saccharomyces cerevisiae S288C	84-89
32029032-1	2019	OBJECTIVE: To investigate whether endogenous nociceptin/orphanin FQ (N/OFQ) can inhibit arrhythmia and expression of beta1-adrenergic receptor (beta1-AR) on the surface of myocardial cell membrane in acute myocardial ischemia rats by Raf kinase inhibitory protein (RKIP).	Nitrogen	69-70	prepronociceptin	Rattus norvegicus	56-67
11454603-8	2001	The selective COX-2 inhibitor N-(2-[cyclohexyloxy]4-nitrophenyl)methanesulfonamide (NS-398, 5 mg/kg), which abolished the protective effect of ischemic late PC, failed to block the protection of either CCPA or IB-MECA, indicating that COX-2 does not mediate the delayed protection of either CCPA or IB-MECA [CCPA + NS-398, 29.1 +/- 3.4% (n = 7); IB-MECA + NS-398, 34.9 +/- 2.9% (n = 8)].	Nitrogen	84-86	prostaglandin G/H synthase 2	Oryctolagus cuniculus	14-19
31628192-3	2019	Here, we found that the N-terminal domain (NTD) of glutamate receptor ionotropic kainate 2 (GluK2) binds complement C1r/C1s-Uegf-BMP (CUB1) domains of Neto proteins (i.e. NTD-CUB1 interaction), and that the core of GluK2 (GluK2DeltaNTD) binds Netos through domains other than CUB1s (core-Neto interaction).	Nitrogen	24-25	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	51-90
31628192-3	2019	Here, we found that the N-terminal domain (NTD) of glutamate receptor ionotropic kainate 2 (GluK2) binds complement C1r/C1s-Uegf-BMP (CUB1) domains of Neto proteins (i.e. NTD-CUB1 interaction), and that the core of GluK2 (GluK2DeltaNTD) binds Netos through domains other than CUB1s (core-Neto interaction).	Nitrogen	24-25	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	92-97
31628192-3	2019	Here, we found that the N-terminal domain (NTD) of glutamate receptor ionotropic kainate 2 (GluK2) binds complement C1r/C1s-Uegf-BMP (CUB1) domains of Neto proteins (i.e. NTD-CUB1 interaction), and that the core of GluK2 (GluK2DeltaNTD) binds Netos through domains other than CUB1s (core-Neto interaction).	Nitrogen	24-25	bone morphogenetic protein 1	Homo sapiens	129-132
31628192-3	2019	Here, we found that the N-terminal domain (NTD) of glutamate receptor ionotropic kainate 2 (GluK2) binds complement C1r/C1s-Uegf-BMP (CUB1) domains of Neto proteins (i.e. NTD-CUB1 interaction), and that the core of GluK2 (GluK2DeltaNTD) binds Netos through domains other than CUB1s (core-Neto interaction).	Nitrogen	24-25	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	215-220
31628192-3	2019	Here, we found that the N-terminal domain (NTD) of glutamate receptor ionotropic kainate 2 (GluK2) binds complement C1r/C1s-Uegf-BMP (CUB1) domains of Neto proteins (i.e. NTD-CUB1 interaction), and that the core of GluK2 (GluK2DeltaNTD) binds Netos through domains other than CUB1s (core-Neto interaction).	Nitrogen	24-25	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	222-235
31751425-5	2019	The facts that phosphorylation of Ser-1072 in FMNL2 has been shown to play a critical role in integrin beta1 internalization mediated by FMNL2 and that Ser-171 in FMNL2 and Ser-174 in FMNL3 are novel putative phosphorylation sites conserved between FMNL2 and FMNL3 indicate that the strategy used in this study is a useful tool for identifying and characterizing physiologically important phosphorylation reactions occurring on N-myristoylated proteins.	Nitrogen	48-49	formin like 2	Homo sapiens	137-142
11454603-8	2001	The selective COX-2 inhibitor N-(2-[cyclohexyloxy]4-nitrophenyl)methanesulfonamide (NS-398, 5 mg/kg), which abolished the protective effect of ischemic late PC, failed to block the protection of either CCPA or IB-MECA, indicating that COX-2 does not mediate the delayed protection of either CCPA or IB-MECA [CCPA + NS-398, 29.1 +/- 3.4% (n = 7); IB-MECA + NS-398, 34.9 +/- 2.9% (n = 8)].	Nitrogen	84-86	prostaglandin G/H synthase 2	Oryctolagus cuniculus	235-240
31751425-5	2019	The facts that phosphorylation of Ser-1072 in FMNL2 has been shown to play a critical role in integrin beta1 internalization mediated by FMNL2 and that Ser-171 in FMNL2 and Ser-174 in FMNL3 are novel putative phosphorylation sites conserved between FMNL2 and FMNL3 indicate that the strategy used in this study is a useful tool for identifying and characterizing physiologically important phosphorylation reactions occurring on N-myristoylated proteins.	Nitrogen	48-49	formin like 2	Homo sapiens	137-142
31751425-5	2019	The facts that phosphorylation of Ser-1072 in FMNL2 has been shown to play a critical role in integrin beta1 internalization mediated by FMNL2 and that Ser-171 in FMNL2 and Ser-174 in FMNL3 are novel putative phosphorylation sites conserved between FMNL2 and FMNL3 indicate that the strategy used in this study is a useful tool for identifying and characterizing physiologically important phosphorylation reactions occurring on N-myristoylated proteins.	Nitrogen	48-49	formin like 2	Homo sapiens	137-142
31734752-1	2019	A glassy carbon electrode (GCE) was modified with nitrogen-enriched carbon frameworks decorated with palladium nanoparticles (Pd@NCF/GCEs).	Nitrogen	50-58	neutrophil cytosolic factor 4	Homo sapiens	129-132
31734752-3	2019	The Pd@NCF was fabricated though one-step pyrolysis and characterized by X-ray photoelectron spectroscopy, X-ray diffraction, scanning electron microscopy and nitrogen-adsorption/desorption analysis.	Nitrogen	159-167	neutrophil cytosolic factor 4	Homo sapiens	7-10
31511384-0	2019	Comprehensive Interactome Analysis Reveals that STT3B is Required for the N-Glycosylation of Lassa Virus Glycoprotein.	Nitrogen	74-75	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	48-53
11513424-3	2001	The software allows the determination of PAH emissions as a function of the fuel composition parameters (aromatic content, cetane index, gross heat power, nitrogen and sulphur content) and operation conditions (torque and engine speed).	Nitrogen	155-163	phenylalanine hydroxylase	Homo sapiens	41-44
31511384-10	2019	The STT3B-dependent N-glycosylation of GP is conserved among other arenaviruses, including both the Old World (OW) and New World (NW) groups.	Nitrogen	20-21	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	4-9
31511384-11	2019	Our study provided a systematic view of LASV GP-host interactions and revealed the preferential requirement of STT3B for LASV GP N-glycosylation.IMPORTANCE Glycoproteins play vital roles in the arenavirus life cycle by facilitating virus entry and participating in the virus budding process.	Nitrogen	129-130	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	111-116
31511384-13	2019	In this study, a comprehensive LASV GP interactome was characterized, and further study revealed that STT3B-dependent N-glycosylation was preferentially required by arenavirus GPs and critical for virus infectivity.	Nitrogen	118-119	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	102-107
31511384-14	2019	The two specific thioredoxin subunits of STT3B-OST MAGT1 and TUSC3 were found to be essential for the N-glycosylation of viral GP.	Nitrogen	102-103	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	41-46
31718088-4	2019	We analyzed the ability of the N-terminal fragments of human CAP1 and CAP2 to assist human isoforms of "muscle" (CFL2) and "non-muscle" (CFL1) cofilins in accelerating actin dynamics.	Nitrogen	31-32	cofilin 2	Homo sapiens	113-117
11485624-1	2001	The V3 region of the human immunodeficiency virus type 1 envelope protein gp120 constitutes a potential neutralization target, but the oligosaccharide of one conserved N-glycosylation site in this region protects it from neutralizing antibodies.	Nitrogen	168-169	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	74-79
31787876-4	2019	Here, we show by deletion analysis that regions required for homomeric interaction of Mover are distributed across the entire molecule, including N-terminal, central and C-terminal regions.	Nitrogen	146-147	tumor protein p63 regulated 1 like	Homo sapiens	86-91
31589236-0	2019	A long-life Li-CO2 battery employing a cathode catalyst of cobalt-embedded nitrogen-doped carbon nanotubes derived from a Prussian blue analogue.	Nitrogen	75-83	complement C2	Homo sapiens	15-18
11780340-7	2001	Somatostatin and growth hormone inhibited inflammatory mediators and TNF alpha mRNA overexpressions, reduced the risk of MODS, corrected hypoalbuminemia, reversed negative nitrogen balance, and controlled the reduction of cell groups with functions and reasonably intervened SIRS caused by ANP.	Nitrogen	172-180	gonadotropin releasing hormone receptor	Rattus norvegicus	17-31
31692471-6	2019	Both divalent sites are compared with those in previous Shh-N structures, which demonstrates a significant degree of plasticity of the Shh-N protein in terms of divalent ion binding.	Nitrogen	60-61	sonic hedgehog signaling molecule	Homo sapiens	56-59
11489133-2	2001	Among them is AGP1 encoding a low-affinity, broad-specificity amino acid permease important for the utilization of amino acids as a nitrogen source.	Nitrogen	132-140	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	14-18
31519107-5	2019	The temporal moment analysis method gave values for the transport parameters tau and R which were significantly correlated with soil parameters related to organic matter, specifically OC and N concentrations.	Nitrogen	191-192	microtubule associated protein tau	Homo sapiens	77-80
31776298-7	2019	To determine the heterogeneity of myeloid cells in peripheral blood samples, we performed the three-dimensional principal component analysis using the combination of GPI-80, CD16, and latency-associated peptide-1 (LAP), derived from the N-terminal region of transforming growth factor-beta1 precursor.	Nitrogen	237-238	LAP	Homo sapiens	214-217
11294842-4	2001	Here we have used exoglycosidase digestion and mass spectrometry to sequence the Asn (N)-linked and Ser/Thr (O)-linked oligosaccharides of human apo(a).	Nitrogen	86-87	lipoprotein(a)	Homo sapiens	145-151
31844685-7	2019	Interestingly, the disordered C- and N- terminal regions of GEMININ were involved in binding to SIX3/SIX6.	Nitrogen	37-38	geminin DNA replication inhibitor	Homo sapiens	60-67
31623211-10	2019	In addition, the structure-activity relationship (SAR) of EI revealed that the "Arg1-Asn2-Hyp3" residues at the N-terminus conferred potency at the muscle-type nAChRs, and the deletion analogue  1-3 EI caused a total loss of activity at the alpha1beta1deltaepsilon nAChR.	Nitrogen	112-113	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	160-165
11386850-6	2001	The predicted Slc19a2 protein, like SLC19A2, was predicted to have 12 transmembrane domains and shared a number of other conserved sequence motifs with the human orthologue, including one potential N-glycosylation site (N(63)) and several potential phosphorylation sites.	Nitrogen	198-199	solute carrier family 19 member 2	Homo sapiens	14-21
31570581-5	2019	Chip/LDB and SSDP both contain N-terminal dimerization domains that constitute the bulk of their structured cores.	Nitrogen	31-32	single stranded DNA binding protein 3	Homo sapiens	13-17
31611575-10	2019	Based on the results of the in silico approach used in the present study, we propose that geldanamycin, 17-AAG and 17-DMAG present an increased tendency to bind to the N-terminal domain of Leishmania amazonensis Hsp83 in comparison to human Hsp90.	Nitrogen	168-169	heat shock protein 90 alpha family class A member 1	Homo sapiens	241-246
11440329-2	2001	One ergogenic aid is creatine, a naturally occurring nitrogen compound found primarily in skeletal muscle.	Nitrogen	53-61	activation induced cytidine deaminase	Homo sapiens	14-17
11327593-2	2001	Some para-substituents on the 4-phenylbutyl side chain attached to the tryptamine nitrogen led to compounds with potent GnRH receptor binding.	Nitrogen	82-90	gonadotropin releasing hormone receptor	Rattus norvegicus	120-133
31564495-9	2019	We further demonstrate that the N terminus (including a YISY motif) of the RALF4 peptide ligand interacts strongly with BUPS-ANX receptors but weakly with LLGs and is essential for its biological function, and its C-terminal region is sufficient for LLG binding.	Nitrogen	32-33	ralf-like 4	Arabidopsis thaliana	75-80
31262603-7	2019	Via treatment with endoglycosidase, it was clearly demonstrated that UGT2A3 was N-glycosylated.	Nitrogen	80-81	UDP glucuronosyltransferase family 2 member A3	Homo sapiens	69-75
30613975-5	2019	Either beta3 -AR activation or its overexpression could increase cellular reactive oxygen species (ROS) and reactive nitrogen species (RNS) levels, in line with significant changes in nitric oxide (NO)-pathway, including increases in the ratios of pNOS3/NOS3 and pGSK-3beta/GSK-3beta, and PKG expression level in cardiomyocytes.	Nitrogen	117-125	UDP glucuronosyltransferase family 1 member A8	Rattus norvegicus	7-12
31050353-0	2019	Arabidopsis ubiquitin-specific proteases UBP12 and UBP13 shape ORE1 levels during leaf senescence induced by nitrogen deficiency.	Nitrogen	109-117	ubiquitin-specific protease 12	Arabidopsis thaliana	41-46
31050353-0	2019	Arabidopsis ubiquitin-specific proteases UBP12 and UBP13 shape ORE1 levels during leaf senescence induced by nitrogen deficiency.	Nitrogen	109-117	ubiquitin-specific protease 13	Arabidopsis thaliana	51-56
31050353-3	2019	Here, we show that UBP12/UBP13 (ubiquitin-specific protease 12/13) antagonize the action of NLA (nitrogen limitation adaptation) E3 ligase to maintain ORE1 homeostasis.	Nitrogen	97-105	ubiquitin-specific protease 12	Arabidopsis thaliana	19-24
31050353-3	2019	Here, we show that UBP12/UBP13 (ubiquitin-specific protease 12/13) antagonize the action of NLA (nitrogen limitation adaptation) E3 ligase to maintain ORE1 homeostasis.	Nitrogen	97-105	ubiquitin-specific protease 13	Arabidopsis thaliana	25-30
31637240-12	2019	Our data also indicate that pathologic mutations in the N-terminus of SANS lead to the loos of SANS binding to IFT-B molecules.	Nitrogen	56-57	USH1 protein network component sans	Homo sapiens	70-74
31637240-12	2019	Our data also indicate that pathologic mutations in the N-terminus of SANS lead to the loos of SANS binding to IFT-B molecules.	Nitrogen	56-57	USH1 protein network component sans	Homo sapiens	95-99
31465226-0	2019	Calculation of 15N NMR Chemical Shifts in a Diversity of Nitrogen-Containing Compounds Using Composite Method Approximation at the DFT, MP2, and CCSD Levels.	Nitrogen	57-65	tryptase pseudogene 1	Homo sapiens	136-139
31050353-12	2019	Our study shows that UBP12/UBP13 counteracts the effect of NLA E3 ligase to accelerate leaf senescence under nitrogen starvation.	Nitrogen	109-117	ubiquitin-specific protease 12	Arabidopsis thaliana	21-26
11302743-6	2001	The results suggest that N-myristoylation of the HIV-1 gag protein is necessary for efficient env protein transportation to the cell surface.	Nitrogen	25-26	Pr55(Gag)	Human immunodeficiency virus 1	55-58
31050353-12	2019	Our study shows that UBP12/UBP13 counteracts the effect of NLA E3 ligase to accelerate leaf senescence under nitrogen starvation.	Nitrogen	109-117	ubiquitin-specific protease 13	Arabidopsis thaliana	27-32
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	35-36	jumonji domain containing 6, arginine demethylase and lysine hydroxylase	Homo sapiens	0-5
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	54-55	jumonji domain containing 6, arginine demethylase and lysine hydroxylase	Homo sapiens	0-5
31374424-1	2019	Herein, a robust docking protocol was developed by using a low-cost workflow to highlight the modulation at ATPase domain from Human Topoisomerase-IIalpha (TOP2A) towards four novel Pd(II)-complexes bearing N,S-donor ligands.	Nitrogen	207-208	DNA topoisomerase II alpha	Homo sapiens	156-161
31533338-0	2019	2-Deoxy-d-Glucose-Induced Metabolic Alteration in Human Oral Squamous SCC15 Cells: Involvement of N-Glycosylation of Axl and Met.	Nitrogen	98-99	AXL receptor tyrosine kinase	Homo sapiens	117-120
31533338-10	2019	Moreover, our data suggest that N-linked glycosylation of Axl and Met may contribute to the maintenance of cancer properties in SCC15 cells.	Nitrogen	32-33	AXL receptor tyrosine kinase	Homo sapiens	58-61
11302743-6	2001	The results suggest that N-myristoylation of the HIV-1 gag protein is necessary for efficient env protein transportation to the cell surface.	Nitrogen	25-26	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	94-97
11349921-4	2001	Exclusively terminal, N-bound transoid thiocyanate bonding is observed with eta1-Odpp (4), eta5/-C5H4Me (6) and eta2-Ph2Pz (7) ligands attached approximately perpendicular to the N...N vector.	Nitrogen	22-23	DNA polymerase iota	Homo sapiens	112-116
30919021-9	2019	These results suggest that N-linked glycosylation of P4HA1 can direct hydroxylation at specific proline residues and affect collagen maturation.	Nitrogen	27-28	prolyl 4-hydroxylase subunit alpha 1	Homo sapiens	53-58
31233051-0	2019	MOF derived CoP-decorated nitrogen-doped carbon polyhedrons/reduced graphene oxide composites for high performance supercapacitors.	Nitrogen	26-34	caspase recruitment domain family member 16	Homo sapiens	12-15
31233051-1	2019	ZIF-67 derived CoP-decorated nitrogen-doped porous carbon (CoP-NPC) polyhedra anchored on reduced graphene oxide (RGO) sheets have been successfully prepared through an efficient pyrolysis-phosphidation-assembly strategy.	Nitrogen	29-37	caspase recruitment domain family member 16	Homo sapiens	15-18
31233051-4	2019	This superior electrochemical performance of CoP-NPC/RGO can be ascribed to its 3D interconnected porous structure and the synergistic effect between CoP and the nitrogen-doped carbon matrix.	Nitrogen	162-170	caspase recruitment domain family member 16	Homo sapiens	45-48
31286669-5	2019	Selective inhibition of FABP4 by BMS309403 at 40 mg/kg/d for 3 days and genetic knockout of FABP4 significantly attenuated the serum creatinine, blood urea nitrogen level and renal tubular damage.	Nitrogen	156-164	fatty acid binding protein 4, adipocyte	Mus musculus	24-29
31286669-5	2019	Selective inhibition of FABP4 by BMS309403 at 40 mg/kg/d for 3 days and genetic knockout of FABP4 significantly attenuated the serum creatinine, blood urea nitrogen level and renal tubular damage.	Nitrogen	156-164	fatty acid binding protein 4, adipocyte	Mus musculus	92-97
11256970-0	2001	The efficiency of N-linked glycosylation of bovine DNase I depends on the Asn-Xaa-Ser/Thr sequence and the tissue of origin.	Nitrogen	18-19	deoxyribonuclease 1	Bos taurus	51-58
31260704-6	2019	The spectral repeatability is characterized by a low coefficient of variations (1.7% and 7.1% for the FA2 and FA2G1 structures, respectively) and allows to detect the N-glycosylation variability resulting from operating conditions during the bioreactor process.	Nitrogen	167-168	FA complementation group B	Homo sapiens	102-105
31244122-2	2019	In sum, we characterized two modes of bonding of [Zn2+-Tz] with CO2/H2O: the interaction is established through (i) a covalent bond between Zn2+ of [Zn2+-Tz] and oxygen atoms of CO2 or H2O and (ii) hydrogen bonds through N-H or C-H of [Zn2+-Tz] and oxygen atoms of H2O or CO2, N-H   O.	Nitrogen	221-222	complement C2	Homo sapiens	64-71
11275476-9	2001	The present study demonstrates that an N-hydroxy derivative of 4-ABP induces oxidative DNA damage through H(2)O(2) in both a cell-free system and in cultured human cells.	Nitrogen	39-40	amine oxidase copper containing 1	Homo sapiens	65-68
31077913-1	2019	A series of nineteen nitrogen-containing lupane triterpenoids was obtained by modification of C2, C3, C20 and C28 positions of betulonic acid and their alpha-glucosidase inhibiting activity was investigated.	Nitrogen	21-29	sucrase-isomaltase	Homo sapiens	152-169
31412868-15	2019	MMP-9 decreased at 3-months at -20  C, and at all times at -80  C and in liquid nitrogen compared to snap frozen (p < 0.0001).	Nitrogen	80-88	matrix metallopeptidase 9	Equus caballus	0-5
31327656-0	2019	Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.	Nitrogen	11-12	CD274 molecule	Homo sapiens	43-48
31327656-0	2019	Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.	Nitrogen	11-12	CD274 molecule	Homo sapiens	82-87
30905597-7	2019	Moreover, structural characterization of endogenous ALCAM N-glycosylation showed abundant permissive structures for Gal-8 binding.	Nitrogen	58-59	galectin 8	Homo sapiens	116-121
31257950-0	2019	Inflammation-induced reactive nitrogen species cause proteasomal degradation of dimeric peroxiredoxin-1 in a mouse macrophage cell line.	Nitrogen	30-38	peroxiredoxin 1	Mus musculus	88-103
31312984-0	2019	Theoretical study on the mechanism of N- and alpha-carbon oxidation of lapatinib catalyzed by cytochrome P450 monooxygenase.	Nitrogen	38-39	cytochrome P450 family 20 subfamily A member 1	Homo sapiens	94-123
30916996-1	2019	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex comprises synaptosome-associated protein of 25 kDa (SNAP25), syntaxin-1a (syx-1), and synaptobrevin 2, which is essential for many physiologic processes requiring membrane fusion.	Nitrogen	12-13	synaptosome associated protein 25	Homo sapiens	100-140
30808234-10	2019	Elevated renal miR-21 expression positively correlated with 24 h urine protein, serum blood urea nitrogen, serum creatinine, and severity of kidney pathology.	Nitrogen	97-105	microRNA 21	Homo sapiens	15-21
30764944-0	2019	Organic/Inorganic Fe3O4@MCM-41@Zr-Piperazine: An Impressive Magnetite Nanocatalyst for N-Tert-Butoxycarbonylation of Amines.	Nitrogen	70-71	telomerase reverse transcriptase	Homo sapiens	89-93
30764944-1	2019	Fe3O4@MCM-41@Zirconium magnetic nanoparticles modified with piperazine (Fe3O4@MCM-41@Zr-piperazine), as a newly reported catalyst, shows excellent catalytic activity in N-Tert-butoxycarbonylation of amines under the mild and solvent-free conditions.	Nitrogen	169-170	telomerase reverse transcriptase	Homo sapiens	171-175
30734924-4	2019	N-homocysteinylation dissociated tau and MAPs from beta-tubulin, and MS analysis showed that it targets lysine residues critical for their binding to beta-tubulin.	Nitrogen	0-1	microtubule associated protein tau	Homo sapiens	33-36
30916996-1	2019	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex comprises synaptosome-associated protein of 25 kDa (SNAP25), syntaxin-1a (syx-1), and synaptobrevin 2, which is essential for many physiologic processes requiring membrane fusion.	Nitrogen	12-13	synaptosome associated protein 25	Homo sapiens	142-148
30916996-1	2019	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex comprises synaptosome-associated protein of 25 kDa (SNAP25), syntaxin-1a (syx-1), and synaptobrevin 2, which is essential for many physiologic processes requiring membrane fusion.	Nitrogen	12-13	syntaxin 1A	Homo sapiens	151-162
30734924-7	2019	Experimental inactivation of MARS prevented the N-homocysteinylation of tau and MAP1, and the dissociation of tau and MAP1 from beta-tubulin and PSD95 in cultured neuroprogenitors.	Nitrogen	48-49	methionyl-tRNA synthetase 1	Homo sapiens	29-33
11096087-10	2001	Therefore, these results define a signaling cascade leading to the expression of APG14 in response to the availability of nitrogen nutrients and suggest that the regulated expression of APG14 contributes to but is not sufficient for the control of autophagy.	Nitrogen	122-130	Atg14p	Saccharomyces cerevisiae S288C	81-86
30734924-7	2019	Experimental inactivation of MARS prevented the N-homocysteinylation of tau and MAP1, and the dissociation of tau and MAP1 from beta-tubulin and PSD95 in cultured neuroprogenitors.	Nitrogen	48-49	microtubule associated protein tau	Homo sapiens	72-75
30734924-8	2019	In conclusion, increased N-homocysteinylation of tau and MAP1 is a mechanism of brain ageing that depends on Hcy concentration and expression of MARS enzyme.	Nitrogen	25-26	microtubule associated protein tau	Homo sapiens	49-52
30734924-8	2019	In conclusion, increased N-homocysteinylation of tau and MAP1 is a mechanism of brain ageing that depends on Hcy concentration and expression of MARS enzyme.	Nitrogen	25-26	Blood pressure QTL 196	Rattus norvegicus	57-61
30734924-8	2019	In conclusion, increased N-homocysteinylation of tau and MAP1 is a mechanism of brain ageing that depends on Hcy concentration and expression of MARS enzyme.	Nitrogen	25-26	methionyl-tRNA synthetase 1	Homo sapiens	145-149
30967352-9	2019	These findings could result in the highest grain yield (5166 kg ha-1) and N uptake (117 kg ha-1) in CM and the lowest in SM treatments (3105 and 61 kg ha-1, respectively).	Nitrogen	74-75	plasma membrane ATPase	Triticum aestivum	91-95
30967352-9	2019	These findings could result in the highest grain yield (5166 kg ha-1) and N uptake (117 kg ha-1) in CM and the lowest in SM treatments (3105 and 61 kg ha-1, respectively).	Nitrogen	74-75	plasma membrane ATPase	Triticum aestivum	91-95
11096087-10	2001	Therefore, these results define a signaling cascade leading to the expression of APG14 in response to the availability of nitrogen nutrients and suggest that the regulated expression of APG14 contributes to but is not sufficient for the control of autophagy.	Nitrogen	122-130	Atg14p	Saccharomyces cerevisiae S288C	186-191
11160179-4	2001	We demonstrate that specific cleavage of GluR3 by granzyme B (GB), a serine protease released by activated immune cells, can generate the GluR3B autoantigenic peptide, but only if an internal N:-linked glycosylation sequon within the GluR3-GB recognition sequence (ISND*S) is not glycosylated.	Nitrogen	192-193	glutamate ionotropic receptor AMPA type subunit 3	Homo sapiens	41-46
30986666-8	2019	Over longer periods, StSp consortium managed to completely decolorize RB-5 (50 mg/L) at optimized conditions of 25-30  C, pH 9, and using glucose and NH4H2PO4 as carbon and nitrogen source respectively, whereas PsGo consortium decolorized RB-5 (50 mg/mL) completely at 37  C, pH 11, and with lactose and NH4H2PO4 used as carbon and nitrogen sources.	Nitrogen	173-181	steroid sulfatase	Homo sapiens	21-25
30986666-8	2019	Over longer periods, StSp consortium managed to completely decolorize RB-5 (50 mg/L) at optimized conditions of 25-30  C, pH 9, and using glucose and NH4H2PO4 as carbon and nitrogen source respectively, whereas PsGo consortium decolorized RB-5 (50 mg/mL) completely at 37  C, pH 11, and with lactose and NH4H2PO4 used as carbon and nitrogen sources.	Nitrogen	332-340	steroid sulfatase	Homo sapiens	21-25
31026500-2	2019	Here, we show that the key nitrogen metabolic enzyme glutamine synthetase (GS) is a S-nitrosation target in Medicago truncatula and characterize the molecular determinants and the effects of this NO-induced modification on different GS isoenzymes.	Nitrogen	27-35	LOC11405318	Medicago truncatula	53-73
11160649-5	2001	Structure activity studies with 30 benzimidazolone derivatives revealed that ethyl and hydrogen groups at the 1 and 3 nitrogen positions, respectively, were critical for the activation of hIK1 K+ channels and that other alkyl groups were not tolerated at these positions without some loss in potency.	Nitrogen	118-126	IKAROS family zinc finger 1	Homo sapiens	188-192
30928749-5	2019	The shipping contribution is about 0.3% of the total phosphorus and 1.25-3.3% of the total nitrogen input to the Baltic Sea, but their impact to the different biogeochemical variables is up to 10%.	Nitrogen	91-99	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	120-123
30928749-6	2019	Excess nitrogen entering the N-limited system of the Baltic Sea slightly alters certain pathways: cyanobacteria growth is compromised due to extra nitrogen available for other functional groups while the biomass of diatoms and especially flagellates increases due to the excess of the limiting nutrient.	Nitrogen	7-15	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	60-63
30928749-6	2019	Excess nitrogen entering the N-limited system of the Baltic Sea slightly alters certain pathways: cyanobacteria growth is compromised due to extra nitrogen available for other functional groups while the biomass of diatoms and especially flagellates increases due to the excess of the limiting nutrient.	Nitrogen	147-155	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	60-63
30928749-7	2019	In terms of the Baltic Sea ecosystem functioning, continuous input of ship-borne nitrogen is compensated by steady decrease of nitrogen fixation and increase of denitrification, which results in stationary level of total nitrogen content in the water.	Nitrogen	81-89	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	23-26
31217306-2	2019	Snf4 is required to release the N-terminal catalytic domain of Snf1 from autoinhibition by the C-terminal regulatory domain, and snf4Delta mutants cannot grow on carbon sources other than glucose.	Nitrogen	32-33	AMP-activated serine/threonine-protein kinase regulatory subunit SNF4	Saccharomyces cerevisiae S288C	0-4
31204479-3	2019	Here we report a combined photoelectron spectroscopy and quantum-chemistry theoretical study of two M B n- clusters from the middle of the transition metal series: Re B8- and Re B9-.	Nitrogen	22-23	IK cytokine	Homo sapiens	164-180
30928749-7	2019	In terms of the Baltic Sea ecosystem functioning, continuous input of ship-borne nitrogen is compensated by steady decrease of nitrogen fixation and increase of denitrification, which results in stationary level of total nitrogen content in the water.	Nitrogen	127-135	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	23-26
30928749-7	2019	In terms of the Baltic Sea ecosystem functioning, continuous input of ship-borne nitrogen is compensated by steady decrease of nitrogen fixation and increase of denitrification, which results in stationary level of total nitrogen content in the water.	Nitrogen	127-135	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	23-26
30976803-6	2019	Finally, we discover indications of a novel functional role for three TFs; Gcn4, Ert1 and Sut1 during nitrogen limited aerobic fermentation.	Nitrogen	102-110	Sut1p	Saccharomyces cerevisiae S288C	90-94
31079452-4	2019	Using the AXL receptor tyrosine kinase (AXL) as a model glycoprotein with multiple N-glycosylation sites, we show that those LCMS features that could be grouped into graph networks on the basis of glycan mass and retention time differences were actually N-glycopeptides with the same peptide backbone but different N-glycan compositions.	Nitrogen	83-84	AXL receptor tyrosine kinase	Homo sapiens	10-13
31079452-4	2019	Using the AXL receptor tyrosine kinase (AXL) as a model glycoprotein with multiple N-glycosylation sites, we show that those LCMS features that could be grouped into graph networks on the basis of glycan mass and retention time differences were actually N-glycopeptides with the same peptide backbone but different N-glycan compositions.	Nitrogen	83-84	AXL receptor tyrosine kinase	Homo sapiens	40-43
23889278-0	2001	Mutational spectrum of N-hydroxy-N-acetyl-4-aminobiphenyl at exon 3 of the HPRT gene.	Nitrogen	23-24	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	75-79
30763810-6	2019	Significant correlation between total EDC abundance and COD contents was detected, and the concentrations of endogenous estrogens (E1, E2, and E3) were positively correlated with total nitrogen (TN) and total phosphorus (TP).	Nitrogen	185-193	small nucleolar RNA, H/ACA box 73A	Homo sapiens	131-145
30925289-6	2019	We also found that N-GQDs activated the cytochrome P450 monooxygenase (e.g. cyp1a) and the associated aryl-hydrocarbon receptor repressors (ahrr1 and ahrr2) in zebrafish embryos.	Nitrogen	19-20	aryl-hydrocarbon receptor repressor b	Danio rerio	150-155
30905471-6	2019	Intraperitoneal administration of TIP peptide reduced inflammation, proteinuria, and blood urea nitrogen.	Nitrogen	96-104	TOR signaling pathway regulator	Homo sapiens	34-37
11180758-4	2001	We analyzed a dinucleotide (CA)n repeat polymorphism located in the flanking region of ERbeta gene in patients with AITDs and in normal subjects.	Nitrogen	4-5	estrogen receptor 2	Homo sapiens	87-93
31021042-3	2019	These are then transformed into Co3 O4 -nanoparticle-decorated porous N-doped carbon fibres (ZIF-Co3 O4 /NCF) through multi-step annealing treatment.	Nitrogen	70-71	neutrophil cytosolic factor 4	Homo sapiens	105-108
31021042-8	2019	The excellent electrocatalytic performance of ZIF-Co3 O4 /NCF is probably due to the abundance of active sites of graphitic carbon-wrapped Co3 O4 nanoparticles, as well as the cross-linked fibrous nitrogen-doped carbon texture.	Nitrogen	197-205	neutrophil cytosolic factor 4	Homo sapiens	58-61
31165063-1	2019	A mu-eta1:eta1-N2-bridged Mo dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N2), cleaves dinitrogen thermally resulting in a crystallographically characterized bis-mu-N-bridged dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N)2.	Nitrogen	15-17	secreted phosphoprotein 1	Homo sapiens	5-9
31165063-1	2019	A mu-eta1:eta1-N2-bridged Mo dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N2), cleaves dinitrogen thermally resulting in a crystallographically characterized bis-mu-N-bridged dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N)2.	Nitrogen	15-17	secreted phosphoprotein 1	Homo sapiens	10-14
31165063-1	2019	A mu-eta1:eta1-N2-bridged Mo dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N2), cleaves dinitrogen thermally resulting in a crystallographically characterized bis-mu-N-bridged dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N)2.	Nitrogen	87-97	secreted phosphoprotein 1	Homo sapiens	5-9
31165063-1	2019	A mu-eta1:eta1-N2-bridged Mo dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N2), cleaves dinitrogen thermally resulting in a crystallographically characterized bis-mu-N-bridged dimer, {(eta5-C5Me5)[N(Et)C(Ph)N(Et)]Mo}2(mu-N)2.	Nitrogen	87-97	secreted phosphoprotein 1	Homo sapiens	10-14
12324708-5	2001	The T/N ratio (the expression level of BRG1 mRNA in tumor tissues relative to those in corresponding nonneoplastic mucosa) in advanced cases of gastric carcinoma (stages III and IV) was significantly higher than that in cases of stage I and II carcinoma (p = 0.029).	Nitrogen	6-7	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	Homo sapiens	39-43
30940687-1	2019	The Arg/N-end rule pathway and Ubr1, a ubiquitin E3 ligase conserved from yeast to humans, is involved in the degradation of misfolded proteins in the cytosol.	Nitrogen	8-9	E3 ubiquitin-protein ligase UBR1	Saccharomyces cerevisiae S288C	31-35
30964249-7	2019	Limits of detection ( S/ N = 3:1) in the SIM mode were found to be in the range of 0.015-0.050 mug mL-1 for organophosphorus esters, 0.010-0.030 mug mL-1 for nerve agents, and 0.050-0.100 mug mL-1 for blister agents.	Nitrogen	25-26	L1 cell adhesion molecule	Mus musculus	99-103
11266597-1	2001	The fold of the murine Sox-5 (mSox-5) HMG box in free solution has been determined by multidimensional NMR using (15)N-labeled protein and has been found to adopt the characteristic twisted L-shape made up of two wings: the major wing comprising helix 1 (F10--F25) and helix 2 (N32--A43), the minor wing comprising helix 3 (P51--Y67) in weak antiparallel association with the N-terminal extended segment.	Nitrogen	103-104	SRY (sex determining region Y)-box 5	Mus musculus	23-28
31070457-9	2019	While evidence for epigenetic regulation remains limited, polycyclic aromatic hydrocarbons (PAH) and nitrogen dioxide (NO2) exposures may alter methylation of breast tumorigenic genes (e.g., EPHB2, LONP1).	Nitrogen	101-109	EPH receptor B2	Homo sapiens	191-196
31070457-9	2019	While evidence for epigenetic regulation remains limited, polycyclic aromatic hydrocarbons (PAH) and nitrogen dioxide (NO2) exposures may alter methylation of breast tumorigenic genes (e.g., EPHB2, LONP1).	Nitrogen	101-109	lon peptidase 1, mitochondrial	Homo sapiens	198-203
30854805-2	2019	In this study, a nitrogen-doped carbon catalyst with high nitrogen content encapsulating cobalt NPs (CoOx @N-C(g)) was synthesized, and characterized in detail by XRD, HRTEM, N2 -physisorption, ICP, CO2 -TPD, and XPS techniques.	Nitrogen	17-25	complement C2	Homo sapiens	199-202
11266597-1	2001	The fold of the murine Sox-5 (mSox-5) HMG box in free solution has been determined by multidimensional NMR using (15)N-labeled protein and has been found to adopt the characteristic twisted L-shape made up of two wings: the major wing comprising helix 1 (F10--F25) and helix 2 (N32--A43), the minor wing comprising helix 3 (P51--Y67) in weak antiparallel association with the N-terminal extended segment.	Nitrogen	103-104	SRY (sex determining region Y)-box 5	Mus musculus	30-36
30299250-7	2019	After MRL/lpr mice were treated with anti-IL-22 monoclonal antibody (mAb) for 12 weeks, significantly less urine protein and lower serum levels of creatinine and urea nitrogen were found.	Nitrogen	167-175	interleukin 22	Mus musculus	42-47
30942563-0	2019	Incorporation of desmocollin-2 into the plasma membrane requires N-glycosylation at multiple sites.	Nitrogen	65-66	desmocollin 2	Homo sapiens	17-30
30942563-3	2019	The molecular structure of the complete extracellular domain (ECD) of DSC2 was recently described, revealing three disulfide bridges, four N-glycosylation sites, and four O-mannosylation sites.	Nitrogen	139-140	desmocollin 2	Homo sapiens	70-74
30942563-5	2019	Here, we generated a set of DSC2 mutants, in which we systematically exchanged all N-glycosylation sites, O-mannosylation sites, and disulfide bridges within the ECD and investigated the resulting subcellular localization by confocal laser scanning microscopy.	Nitrogen	83-84	desmocollin 2	Homo sapiens	28-32
30942563-8	2019	Colocalization analysis using cell compartment trackers revealed that N-glycosylation- deficient DSC2 mutants were retained within the Golgi apparatus.	Nitrogen	70-71	desmocollin 2	Homo sapiens	97-101
30942563-10	2019	These experiments underscore the importance of N-glycosylation at multiple sites of DSC2 for efficient intracellular transport to the plasma membrane.	Nitrogen	47-48	desmocollin 2	Homo sapiens	84-88
30803063-3	2019	The as-prepared single atoms, supported by N-doped carbon flake arrays grown on carbon nanofibers assembly (M SA@NCF/CNF), demonstrate the dual characteristics of excellent catalytic activity (reversible oxygen overpotential of 0.75 V) and high stability, owing to the greatly improved active sites" accessibility and optimized single-sites/pore-structures correlations.	Nitrogen	43-44	neutrophil cytosolic factor 4	Homo sapiens	113-116
11152930-8	2000	Results showed that P-selectin protein expression was not influenced by n-LDL, but was moderately increased by ox-LDL and n-Lp(a).	Nitrogen	29-30	lipoprotein(a)	Homo sapiens	124-129
31228936-4	2019	The Gln3 protein, which is one of the key regulators of nitrogen metabolism in S. cerevisiae, contains an amyloidogenic region manifesting prion-like properties.	Nitrogen	56-64	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	4-8
11152930-11	2000	Northern blot analysis demonstrated that the amount of P-selectin mRNA was markedly increased after treatment with ox-Lp(a) but not with n-LDL, ox-LDL and n-Lp(a).	Nitrogen	7-8	lipoprotein(a)	Homo sapiens	115-123
11152930-11	2000	Northern blot analysis demonstrated that the amount of P-selectin mRNA was markedly increased after treatment with ox-Lp(a) but not with n-LDL, ox-LDL and n-Lp(a).	Nitrogen	7-8	lipoprotein(a)	Homo sapiens	118-123
11114886-5	2000	HAC1 splicing occurred in a nitrogen-rich environment but ceased rapidly on nitrogen starvation.	Nitrogen	28-36	transcription factor HAC1	Saccharomyces cerevisiae S288C	0-4
30976474-1	2019	Two novel N-embedded polycyclic units functionalized phosphorescent iridium(III) complexes (Ir-1 and Ir-2) with substituents in different positions have been prepared.	Nitrogen	10-11	nischarin	Homo sapiens	92-105
11114886-5	2000	HAC1 splicing occurred in a nitrogen-rich environment but ceased rapidly on nitrogen starvation.	Nitrogen	76-84	transcription factor HAC1	Saccharomyces cerevisiae S288C	0-4
11114886-6	2000	Further, addition of ammonium salts to nitrogen-starved cells was sufficient to rapidly reactivate HAC1 splicing.	Nitrogen	39-47	transcription factor HAC1	Saccharomyces cerevisiae S288C	99-103
11073899-1	2000	Nitrogen-catabolic gene expression in Saccharomyces cerevisiae is regulated by the action of four GATA family transcription factors: Gln3p and Gat1p/Nil1p are transcriptional activators, and Dal80 and Deh1p/Gzf3p are repressors.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	143-148
11073899-1	2000	Nitrogen-catabolic gene expression in Saccharomyces cerevisiae is regulated by the action of four GATA family transcription factors: Gln3p and Gat1p/Nil1p are transcriptional activators, and Dal80 and Deh1p/Gzf3p are repressors.	Nitrogen	0-8	Gat1p	Saccharomyces cerevisiae S288C	149-154
11073899-1	2000	Nitrogen-catabolic gene expression in Saccharomyces cerevisiae is regulated by the action of four GATA family transcription factors: Gln3p and Gat1p/Nil1p are transcriptional activators, and Dal80 and Deh1p/Gzf3p are repressors.	Nitrogen	0-8	Gzf3p	Saccharomyces cerevisiae S288C	201-206
11073899-1	2000	Nitrogen-catabolic gene expression in Saccharomyces cerevisiae is regulated by the action of four GATA family transcription factors: Gln3p and Gat1p/Nil1p are transcriptional activators, and Dal80 and Deh1p/Gzf3p are repressors.	Nitrogen	0-8	Gzf3p	Saccharomyces cerevisiae S288C	207-212
10942758-2	2000	Here we address the extent to which N-glycosylation contributes to assembly, surface appearance, and ligand recognition of P2X(1) receptors.	Nitrogen	36-37	purinergic receptor P2X 1	Rattus norvegicus	123-129
10942758-8	2000	If three or all four N-glycosylation sites are simultaneously eliminated, formation of P2X(1) receptors is severely impaired or abolished, respectively.	Nitrogen	21-22	purinergic receptor P2X 1	Rattus norvegicus	87-93
11040226-10	2000	Pretreatment with the NO synthase inhibitor N:(omega)-nitro-L-arginine methyl ester (L-NAME, 100 micromol/L) blocked leptin-induced inhibition of both peak shortening and fluorescence intensity change.	Nitrogen	22-23	leptin	Rattus norvegicus	117-123
10889209-3	2000	Both GIRK1 and GIRK4 have one extracellular consensus N-glycosylation site.	Nitrogen	54-55	potassium inwardly rectifying channel subfamily J member 3	Homo sapiens	5-10
10985775-5	2000	AICAR analogues where the nitrogen of the 4-carboxamide was derivatized with a methyl or an allylic group did not bind AICAR Tfase, as determined by pre-steady-state burst kinetics; however, these compounds were potent inhibitors of IMP cyclohydrolase (IMP CHase), a second activity of the bifunctional mammalian enzyme (K(i) = 0.05 +/- 0.02 microM for 4-N-allyl-AlCAR).	Nitrogen	26-34	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	Homo sapiens	0-5
30909508-4	2019	Zoledronate, a nitrogen-containing bisphosphonate, markedly increased both the receptor activator of nuclear factor kB ligand (RANKL) as well as sclerostin in osteocyte-like MLO-Y4 cells, which were functionally revalidated by osteoclast/osteoblast generating activities of the conditioned medium obtained from zoledronate-treated MLO-Y4 cells.	Nitrogen	15-23	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	79-125
30909508-4	2019	Zoledronate, a nitrogen-containing bisphosphonate, markedly increased both the receptor activator of nuclear factor kB ligand (RANKL) as well as sclerostin in osteocyte-like MLO-Y4 cells, which were functionally revalidated by osteoclast/osteoblast generating activities of the conditioned medium obtained from zoledronate-treated MLO-Y4 cells.	Nitrogen	15-23	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	127-132
30801341-2	2019	Importantly, many of these ECM molecules display N- and O-linked glycan residues and are considered as potential targets for galectin-1 (Gal-1) and galectin-3 (Gal-3).	Nitrogen	49-50	galectin 1	Homo sapiens	137-142
32172744-8	2019	The NO3- content and nitrate reductase (NR) activity of maize leaves were significantly reduced under drought stress, while moderate nitrogen supply promoted the accumulation of NO3- and an increase in the nitrate reductase activity.	Nitrogen	133-141	nitrate reductase [NADH] 1	Zea mays	206-223
30642881-0	2019	ACBD6 protein controls acyl chain availability and specificity of the N-myristoylation modification of proteins.	Nitrogen	70-71	acyl-CoA binding domain containing 6	Homo sapiens	0-5
30642881-9	2019	Thus, ACBD6 proteins promote N-myristoylation in mammalian cells and in one of their intracellular parasites under unfavorable substrate-limiting conditions.	Nitrogen	29-30	acyl-CoA binding domain containing 6	Homo sapiens	6-11
30824566-0	2019	The Chromatin Factor HNI9 and ELONGATED HYPOCOTYL5 Maintain ROS Homeostasis under High Nitrogen Provision.	Nitrogen	87-95	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	21-25
31002798-3	2019	Here, we show that the PNG-1/NGLY1 peptide:N-glycanase edits the sequence of SKN-1A protein by converting particular N-glycosylated asparagine residues to aspartic acid.	Nitrogen	24-25	N-glycanase 1	Homo sapiens	29-34
31002798-3	2019	Here, we show that the PNG-1/NGLY1 peptide:N-glycanase edits the sequence of SKN-1A protein by converting particular N-glycosylated asparagine residues to aspartic acid.	Nitrogen	24-25	N-glycanase 1	Homo sapiens	35-54
31002798-3	2019	Here, we show that the PNG-1/NGLY1 peptide:N-glycanase edits the sequence of SKN-1A protein by converting particular N-glycosylated asparagine residues to aspartic acid.	Nitrogen	24-25	POU class 2 homeobox 3	Homo sapiens	77-83
31002798-4	2019	Genetically introducing aspartates at these N-glycosylation sites bypasses the requirement for PNG-1/NGLY1, showing that protein sequence editing rather than deglycosylation is key to SKN-1A function.	Nitrogen	44-45	POU class 2 homeobox 3	Homo sapiens	184-190
30916544-6	2019	A nitrosyl normally coordinates through its N atom (eta1-NO) but when photoactivated can undergo isomerism and coordinate through its O atom (eta1-ON).	Nitrogen	44-45	secreted phosphoprotein 1	Homo sapiens	52-56
30808544-0	2019	Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.	Nitrogen	14-15	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	59-63
30808544-5	2019	Furthermore, the N-fucosylation-related genes FUT3, 5, and 6 were found to be responsible for the elevated fucosylation in metastatic pancreatic cells through real-time PCR screening.	Nitrogen	17-18	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	46-50
30672316-7	2019	A lack of PAR2 corrected the levels of plasma blood urea nitrogen and creatinine as well as ameliorated the acute tubular injury score in the kidney.	Nitrogen	57-65	coagulation factor II (thrombin) receptor-like 1	Mus musculus	10-14
30674553-8	2019	Furthermore, we show that the loss of the components of the Arg/N-end rule pathway substantially suppresses the growth defects of naa20Delta yeast cells lacking the catalytic subunit of NatB Nt acetylase at 37  C. Collectively, the results of our study reveal that NME is a key upstream step for the creation of the Arg/N-end rule substrates bearing tertiary destabilizing residues in vivo.	Nitrogen	64-65	peptide alpha-N-acetyltransferase complex B subunit NAT3	Saccharomyces cerevisiae S288C	130-135
30674553-8	2019	Furthermore, we show that the loss of the components of the Arg/N-end rule pathway substantially suppresses the growth defects of naa20Delta yeast cells lacking the catalytic subunit of NatB Nt acetylase at 37  C. Collectively, the results of our study reveal that NME is a key upstream step for the creation of the Arg/N-end rule substrates bearing tertiary destabilizing residues in vivo.	Nitrogen	186-187	peptide alpha-N-acetyltransferase complex B subunit NAT3	Saccharomyces cerevisiae S288C	130-135
30711708-7	2019	The exposure of A549 cells to Ag/N-TiO2 NPs determine the activation of ERK1/2 MAP-kinase pathway and the release of pro-inflammatory mediators CXCL1, GM-CSF and MIF, known to be involved in the recruitment of circulating neutrophils and monocytes.	Nitrogen	33-34	colony stimulating factor 2	Homo sapiens	151-157
30876481-10	2019	RESULTS: ADSCs-Exo attenuated spontaneous diabetes by reducing levels of urine protein, serum creatinine (Scr), blood urea nitrogen (BUN), and podocyte apoptosis in mice.	Nitrogen	123-131	5'-3' exoribonuclease 1	Mus musculus	15-18
30724565-1	2019	The effect of single amino acid mutations on the rebinding dynamics of nitrogen monoxide (NO) to myoglobin is investigated using reactive molecular dynamics simulations.	Nitrogen	71-79	myoglobin	Homo sapiens	97-106
30371011-1	2019	In contrast to well-recognized protein phosphorylation on the side-chain oxygen of Ser, Thr, or Tyr residues, analogous phosphoramidation of the nitrogen of His, Lys, and Arg side chains remains much less investigated, mainly due to the instability of post-translational modifications and technical difficulties involved in their analysis.	Nitrogen	145-153	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	171-174
30783169-0	2019	Novel model of secreted human tau protein reveals the impact of the abnormal N-glycosylation of tau on its aggregation propensity.	Nitrogen	0-1	microtubule associated protein tau	Homo sapiens	30-33
30783169-0	2019	Novel model of secreted human tau protein reveals the impact of the abnormal N-glycosylation of tau on its aggregation propensity.	Nitrogen	0-1	microtubule associated protein tau	Homo sapiens	96-99
30783169-3	2019	Tau undergoes several posttranslational modifications, including N-glycosylation.	Nitrogen	65-66	microtubule associated protein tau	Homo sapiens	0-3
30783169-4	2019	Tau was reported to be N-glycosylated in AD brains, but not in healthy counterparts, which may affect AD etiology.	Nitrogen	23-24	microtubule associated protein tau	Homo sapiens	0-3
30783169-5	2019	Here, we aimed to examine the effect of N-glycosylation on aggregation propensity of tau.	Nitrogen	40-41	microtubule associated protein tau	Homo sapiens	85-88
30781796-7	2019	Removing all potential N-glycosylation sites from the C2V3 domain by site-specific mutagenesis reversed the vaccine-induced immune response towards a Th1-dominated T-cell response and a balanced IgG2a/IgG1 ratio.	Nitrogen	23-24	immunoglobulin heavy variable V1-9	Mus musculus	195-200
30547227-13	2019	In a longitudinal cohort, CSF N-224 tau levels were stable over 6 months, with no significant effect of treatment with AChE inhibitors.	Nitrogen	30-31	microtubule associated protein tau	Homo sapiens	36-39
30485160-4	2019	Here we show that active Gtr1/2 is a potent inhibitor of TORC1-body formation, but cells missing Gtr1/2 still form TORC1-bodies in a glucose/nitrogen starvation-dependent manner.	Nitrogen	141-149	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	97-103
30605203-1	2019	Ru nanoparticles doped in carbon foam were encapsulated in nitrogen-doped graphite carbon materials (Ru-NGC).	Nitrogen	59-67	chondroitin sulfate proteoglycan 5	Homo sapiens	104-107
11034551-0	2000	N-glycosylation contributes to the limited cross-reactivity between hemagglutinin neuraminidase proteins of human parainfluenza virus type 4A and 4B.	Nitrogen	0-1	hemagglutinin-neuraminidase	Human parainfluenza virus 4a	68-95
11053990-4	2000	The T/N ratio of Mn-SOD mRNA expression was less than 0.5 in 11 (32.4%) of 34 esophageal carcinoma cases without any preoperative treatments, while none of 11 cases who underwent preoperative chemotherapy showed a T/N ratio of &lt;0.5 (p &lt; 0.05).	Nitrogen	6-7	superoxide dismutase 2	Homo sapiens	17-23
30842982-2	2019	In the lactic acid bacteria Lactococcus lactis, the oligopeptide-binding protein A (OppA) binds peptides for import to support nitrogen metabolism and cell growth.	Nitrogen	127-135	OppA	Lactococcus lactis	84-88
11053990-4	2000	The T/N ratio of Mn-SOD mRNA expression was less than 0.5 in 11 (32.4%) of 34 esophageal carcinoma cases without any preoperative treatments, while none of 11 cases who underwent preoperative chemotherapy showed a T/N ratio of &lt;0.5 (p &lt; 0.05).	Nitrogen	26-27	superoxide dismutase 2	Homo sapiens	17-23
30742181-5	2019	More excitingly, 406 N-glycosylation peptides corresponding to 185 glycoproteins were identified in the urine of the bladder cancer patients, in which these identified glycoproteins include the potential biomarkers (alpha-2-macroglobulin, complement C4-B, and alpha-1-antitrypsin) for the bladder cancer.	Nitrogen	21-22	alpha-2-macroglobulin	Homo sapiens	216-237
10906059-2	2000	The encoded proteins of the two novel clones, designated prolactin-like proteins L (PLP-L) and M (PLP-M), are predicted to be synthesized as precursors of 229 and 227 amino acids, modified by N-linked glycosylation, and secreted as mature glycoproteins of 199 and 200 residues, respectively.	Nitrogen	192-193	prolactin family 2, subfamily A, member 1	Rattus norvegicus	98-103
30770792-3	2019	Smac mimetics such as BV6 selectively inhibit apoptosis triggered by pharmacological or genetic inhibition of protein N-glycosylation using TM or knockdown of DPAGT1, the enzyme that catalyzes the first step of protein N-glycosylation.	Nitrogen	118-119	diablo IAP-binding mitochondrial protein	Homo sapiens	0-4
30770792-3	2019	Smac mimetics such as BV6 selectively inhibit apoptosis triggered by pharmacological or genetic inhibition of protein N-glycosylation using TM or knockdown of DPAGT1, the enzyme that catalyzes the first step of protein N-glycosylation.	Nitrogen	219-220	diablo IAP-binding mitochondrial protein	Homo sapiens	0-4
10901703-7	2000	Similarly, the ratio of FMO to CYP metabolites of tamoxifen decreased due to a reduction in N-oxygenation.	Nitrogen	92-93	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	31-34
30996807-6	2019	We show that the shift of the alkyl chain from the endocyclic nitrogen to the C-2 position leads to a considerable increase in chaperoning efficacy, affording a new compound (4a) able to induce a remarkable 1.9-fold maximal increase in GCase activity.	Nitrogen	62-70	complement C2	Homo sapiens	78-81
30788440-5	2019	The HSulf-2 protein sequence was determined by Nano-LC-MS/MS, leading to 63% coverage and indicating at least four N-glycosylation sites at Asn 108, 147, 174 and 217.	Nitrogen	47-48	sulfatase 2	Homo sapiens	4-11
10903367-0	2000	Molecular evolution of nitrogen fixation: the evolutionary history of the nifD, nifK, nifE, and nifN genes.	Nitrogen	23-31	nucleolar protein interacting with the FHA domain of MKI67	Homo sapiens	80-84
30736465-1	2019	The strongly fluorescent and highly catalytic N-doped carbon dots (CDN) were rapidly prepared by a microwave irradiation procedure and were characterized by electron microscopy (EM), laser scattering, infrared spectroscopy (IR), and by their fluorescence spectrum.	Nitrogen	46-47	5', 3'-nucleotidase, cytosolic	Homo sapiens	67-70
10828016-4	2000	Previously, it was found that N-glycosylation of GMRalpha is essential for ligand binding.	Nitrogen	30-31	colony stimulating factor 2 receptor subunit alpha	Homo sapiens	49-57
30728400-0	2019	The ability to utilise ammonia as nitrogen source is cell type specific and intricately linked to GDH, AMPK and mTORC1.	Nitrogen	34-42	glutamate dehydrogenase 1	Homo sapiens	98-101
30728400-11	2019	The ability of cells to utilise ammonia as a nitrogen source is intricately linked to AMPK, mTORC1 and GDH.	Nitrogen	45-53	glutamate dehydrogenase 1	Homo sapiens	103-106
10807976-5	2000	Results showed that PDGF-B expression was not influenced by n-LDL, but was moderately increased by ox-LDL and n-Lp(a).	Nitrogen	36-37	lipoprotein(a)	Homo sapiens	112-117
30463977-4	2019	We have found that KSHV infection accelerates nitrogen efflux by upregulating the expression of argininosuccinate synthase 1 (ASS1), a key enzyme in the citrulline-NO cycle.	Nitrogen	46-54	argininosuccinate synthase 1	Homo sapiens	96-124
30463977-4	2019	We have found that KSHV infection accelerates nitrogen efflux by upregulating the expression of argininosuccinate synthase 1 (ASS1), a key enzyme in the citrulline-NO cycle.	Nitrogen	46-54	argininosuccinate synthase 1	Homo sapiens	126-130
30605203-2	2019	The resultant Ru-NGC possesses superior hydrogen evolution activity with a small onset potential of 9.5 mV and excellent durability due to the optimized Ru electronic state in nitrogen-doped graphite.	Nitrogen	176-184	chondroitin sulfate proteoglycan 5	Homo sapiens	17-20
10725556-7	2000	After 20 days of stress (50 DAP), N content increased in NH(4)NO(3)-sufficient but not in N(2)-fixing beans, despite the latter"s lesser state of wilt.	Nitrogen	34-35	death associated protein	Homo sapiens	28-31
31950742-2	2019	Separation of the piperidine nitrogen atoms in CC3 is considerably larger at 14.36 A than previously reported tripodal opioids allowing for enhanced aggregation of larger DNA plasmids (>4,000 bp).	Nitrogen	29-37	C-C motif chemokine ligand 14	Homo sapiens	47-50
31939153-1	2019	p97 belongs to the functional diverse superfamily of AAA+ (ATPases Associated with diverse cellular Activities) ATPases and is characterized by an N-terminal regulatory domain and two stacked hexameric ATPase domains forming a central protein conducting channel.	Nitrogen	147-148	melanotransferrin	Homo sapiens	0-3
30740912-3	2019	NGLY1 encodes the cytosolic enzyme N-glycanase 1, which is responsible for the deglycosylation of misfolded N-glycosylated proteins.	Nitrogen	35-36	N-glycanase 1	Homo sapiens	0-5
31459457-2	2019	Here, a series of nitrogen-doped (N-doped) activated carbon catalysts (N-AC) were prepared conveniently for EDC dehydrochlorination.	Nitrogen	18-26	synuclein alpha	Homo sapiens	71-75
10769182-0	2000	Mutational analysis of the N-linked glycosylation sites of the human insulin receptor.	Nitrogen	27-28	insulin receptor	Homo sapiens	69-85
30601658-5	2019	Moreover, the highly conductive NbN and N-doped graphene nanosheets provide rapid electron transport and consequently, the S/NbN@NG cathode demonstrates a large capacity of 948 mAh g-1 at 1 C (1 C = 1650 mA g-1), high rate capability of 739 mAh g-1 at 5 C, and excellent cycle stability with a capacity decay of 0.09% per cycle for over 400 cycles.	Nitrogen	32-33	nibrin	Homo sapiens	125-128
30512947-4	2018	Importantly, the incorporation of Mg2+ and Co2+ ions in the framework of AlPO-ERI can greatly improve the adsorption selectivities of CO2 over CH4 and N2.	Nitrogen	151-153	complement C2	Homo sapiens	43-46
10823661-5	2000	Furthermore, since the stability of N-glycosylated proteins is known to be regulated by lectin family chaperones, such as calnexin, a type I transmembrane protein located in the endoplasmic reticulum (ER), and calreticulin, a soluble protein in the ER lumen, the effect of the processing inhibitors on the interaction of IFN-gamma with calnexin and calreticulin was investigated.	Nitrogen	36-37	calnexin	Homo sapiens	122-130
30558146-0	2018	Knockout of SlSBPASE Suppresses Carbon Assimilation and Alters Nitrogen Metabolism in Tomato Plants.	Nitrogen	63-71	chloroplast sedoheptulose-1,7-bisphosphatase	Solanum lycopersicum	12-20
30558146-7	2018	Intriguingly, mutation in SlSBPASE altered nitrogen metabolism as demonstrated by changes in levels of protein and amino acids and activities of nitrogen metabolic enzymes.	Nitrogen	43-51	chloroplast sedoheptulose-1,7-bisphosphatase	Solanum lycopersicum	26-34
10823661-5	2000	Furthermore, since the stability of N-glycosylated proteins is known to be regulated by lectin family chaperones, such as calnexin, a type I transmembrane protein located in the endoplasmic reticulum (ER), and calreticulin, a soluble protein in the ER lumen, the effect of the processing inhibitors on the interaction of IFN-gamma with calnexin and calreticulin was investigated.	Nitrogen	36-37	calnexin	Homo sapiens	336-344
30558146-7	2018	Intriguingly, mutation in SlSBPASE altered nitrogen metabolism as demonstrated by changes in levels of protein and amino acids and activities of nitrogen metabolic enzymes.	Nitrogen	145-153	chloroplast sedoheptulose-1,7-bisphosphatase	Solanum lycopersicum	26-34
30558146-8	2018	Collectively, our data suggest that SlSBPASE is required for optimal growth, carbon assimilation and nitrogen metabolism in tomato plants.	Nitrogen	101-109	chloroplast sedoheptulose-1,7-bisphosphatase	Solanum lycopersicum	36-44
30092607-4	2018	Six N-glycosylation sites are presumed to exist in the extracellular domain of GluA1, which is a member of the AMPA-R subunits.	Nitrogen	4-5	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	79-84
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	121-127
30376305-4	2019	X-ray protein crystallography of the {[Pt(ppy)(PPh3)]/ubiquitin} conjugate revealed direct bonding of the platinum center to unique histidine-68 residue through the nitrogen atom of imidazole function, the coordination being also supported by noncovalent interaction of the ligands with the protein secondary structure.	Nitrogen	165-173	protein phosphatase 4 catalytic subunit	Homo sapiens	47-51
30571087-2	2019	A similar procedure aimed at synthesizing a Nb/Co analogue instead affords iPrN Nb( iPrNPPh2)2(mu-PPh2)Co-I (3) through cleavage of one phosphinoamide P-N bond under reducing conditions.	Nitrogen	44-45	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	103-107
10840970-4	2000	When the PhPN ligand is present in excess, it behaves as a monodentate phosphane ligand, since [Pd0(eta2-dba)(eta1-PhPN)2] is formed first by preferential cleavage of the Pd-N bond instead of the Pd olefin bond.	Nitrogen	12-13	DNA polymerase iota	Homo sapiens	100-104
30576160-1	2019	A useful catalytic enantioselective approach has been developed for the synthesis of chiral ketamine analogs using Rh(II)-catalyzed amination of triisopropylsilyl enol ethers to form alpha-amino ketones with O-(4-nitrophenyl)hydroxylamine as nitrogen donor in 81-91% ee.	Nitrogen	242-250	Rh blood group D antigen	Homo sapiens	115-120
30342419-2	2019	In this study, separation performances of 153 COFs, 14 IRMOFs and 8 ZIFs were assessed for efficient removal of carbon tetrachloride (CCl4) from CCl4/Ar, CCl4/N2, CCl4/O2 mixtures at 298 K and infinite dilution.	Nitrogen	159-161	C-C motif chemokine ligand 4	Homo sapiens	134-138
30431044-5	2018	Attributed to the synergistic effects of N,S co-doping, the high specific surface area and the interconnected porous architecture, NSHC demonstrates excellent catalytic activity and selectivity in the reduction of nitroarenes.	Nitrogen	41-42	SHC adaptor protein 3	Homo sapiens	131-135
10747782-10	2000	Changes in the backbone amide proton and nitrogen chemical shifts upon DNA binding have enabled us to experimentally define a DNA-binding surface on the core N-terminal domain of Mbp1 that is associated with a putative winged helix-turn-helix motif.	Nitrogen	41-49	transcription factor MBP1	Saccharomyces cerevisiae S288C	179-183
30482831-3	2018	The present work analyzes an ArcB-independent growth defect of a sixA deletion in E. coli A screen for suppressors, analysis of various mutants, and phosphorylation assays indicate that SixA modulates phosphorylation of the nitrogen-related phosphotransferase system (PTSNtr).	Nitrogen	224-232	hypothetical protein	Escherichia coli	29-33
30713787-0	2019	The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex.	Nitrogen	27-28	CD274 molecule	Homo sapiens	75-80
31555023-3	2019	The authors give values of the coefficients c 1, c 2, c 3 for six gases: Ne, Ar, Xe, N2, CO2, and N2O.	Nitrogen	85-87	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	44-57
10784435-4	2000	Bisphenol A (1 mM) most efficiently inhibited aminopyrine N-demethylation by CYP2C8 and CYP2C19 by 82% and 85%, respectively, whereas inhibition of the activities by CYP 2B6 and 2D6 was less than 40%.	Nitrogen	58-59	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	77-83
30427198-3	2018	Using NMR and X-ray crystallography, it is shown that glucosyl carbasugar alpha-aziridines can act as reasonably potent endo-alpha-mannosidase inhibitors, likely by virtue of their shape mimicry and the interactions of the aziridine nitrogen with the conserved catalytic acid/base of the enzyme active site.	Nitrogen	233-241	mannosidase endo-alpha	Homo sapiens	120-142
10805445-5	2000	LIMP 2 is also a nodulin, showing expression only in mature nitrogen fixing nodules of L. japonicus.	Nitrogen	60-68	LIMP2	Lotus japonicus	0-6
30515097-4	2018	Clofazimine, but neither isoniazid nor rifampicin, caused dose-related potentiation of both ADP- and thrombin-activated expression of CD62P by platelets, achieving statistical significance at threshold concentrations of 0.625 and 2.5 mg/L, respectively, as well as significant formation of N:P aggregates.	Nitrogen	290-291	selectin P	Homo sapiens	134-139
30428359-4	2018	HO-1 mitigates TB pathophysiology by diminishing myeloid cell-mediated oxidative damage caused by reactive oxygen and/or nitrogen intermediates, which control granulocytic karyorrhexis to generate a zonal HO-1 response.	Nitrogen	121-129	heme oxygenase 1	Homo sapiens	0-4
10808272-5	2000	Using this system, the role of N-glycosylation in pIgA-pIgR binding was examined.	Nitrogen	31-32	polymeric immunoglobulin receptor	Mus musculus	55-59
30483512-5	2018	Studies on these organisms yielded a first structure of a PII complex with an enzyme, (N-acetyl-Lglutamate kinase, NAGK), deciphering how PII can cause enzyme activation, and how it promotes nitrogen stockpiling as arginine in cyanobacteria and plants.	Nitrogen	191-199	N-acetylglucosamine kinase	Homo sapiens	115-119
10808272-6	2000	The pIgR molecule (molecular mass 100 kDa) after complete deglycosylation by tunicamycin treatment was still able to bind to pIgA, indicating that N-glycosylation of pIgR is not necessary for pIgA-pIgR binding.	Nitrogen	147-148	polymeric immunoglobulin receptor	Mus musculus	4-8
10712537-1	2000	Using Arabidopsis, we analyzed the effect of omission of a nitrogen source and of the addition of different nitrogen-containing compounds on the extractable activity and the enzyme and mRNA accumulation of adenosine 5"-phosphosulfate reductase (APR).	Nitrogen	108-116	5'adenylylphosphosulfate reductase 2	Arabidopsis thaliana	206-243
30268856-4	2018	KEY FINDINGS: Pkd1 miRNA transgenic (Pkd1 miR TG) mice treated with 1 mg/kg/day of celastrol exhibited a lower renal cystic index (by 21.5%) than the vehicle-treated controls, but the fractional kidney weights and blood urea nitrogen levels were not significantly affected with celastrol treatment.	Nitrogen	225-233	polycystin 1, transient receptor potential channel interacting	Mus musculus	14-18
10712537-2	2000	During 72 h without a nitrogen source, the APR activity decreased to 70% and 50% of controls in leaves and roots, respectively, while cysteine (Cys) and glutathione contents were not affected.	Nitrogen	22-30	5'adenylylphosphosulfate reductase 2	Arabidopsis thaliana	43-46
10794450-1	2000	Emission spectra from a DC plasma discharge of nitrogen with a graphite cathode used for deposition of CNx layers were investigated in the visible range 350-900 nm.	Nitrogen	47-55	calnexin	Homo sapiens	103-106
10683445-6	2000	However, inhibition of N-linked glycosylation results in aberrant trafficking of the alpha- and beta-dystroglycan subunits to the plasma membrane.	Nitrogen	23-24	dystroglycan 1	Homo sapiens	101-113
10684962-7	1999	In addition, the CD23a" and CD23b" molecules in transfected COS cells were resistant to Endo H(f) and PNGase F, although these truncated forms as well as the membrane-associated forms had an asparagine residue responsible for the N-linked glycosylation.	Nitrogen	103-104	Fc epsilon receptor II	Homo sapiens	17-22
10541284-9	1999	Evaluation of COX-2 mRNA expression by Northern blot analysis after NS-398 treatment demonstrated that the COX-2 protein upregulation occurred independently of any change in COX-2 mRNA expression.	Nitrogen	68-70	cytochrome c oxidase II, mitochondrial	Mus musculus	14-19
10541284-9	1999	Evaluation of COX-2 mRNA expression by Northern blot analysis after NS-398 treatment demonstrated that the COX-2 protein upregulation occurred independently of any change in COX-2 mRNA expression.	Nitrogen	68-70	cytochrome c oxidase II, mitochondrial	Mus musculus	107-112
10541284-9	1999	Evaluation of COX-2 mRNA expression by Northern blot analysis after NS-398 treatment demonstrated that the COX-2 protein upregulation occurred independently of any change in COX-2 mRNA expression.	Nitrogen	68-70	cytochrome c oxidase II, mitochondrial	Mus musculus	107-112
10514491-4	1999	Diploid cells lacking Gpr1p, Plc1p, or Gpa2p fail to form pseudohyphae upon nitrogen depletion, and the filamentation defect of gpr1Delta and plc1Delta strains is rescued by activating a mitogen-activated protein kinase pathway via STE11-4 or by activating a cAMP pathway via overexpressed Tpk2p.	Nitrogen	76-84	phosphatidylinositol phospholipase C	Saccharomyces cerevisiae S288C	29-34
10514491-5	1999	Plc1p is also required for efficient expression of the FG(TyA)::lacZ reporter gene under nitrogen depletion.	Nitrogen	89-97	phosphatidylinositol phospholipase C	Saccharomyces cerevisiae S288C	0-5
10514491-6	1999	In conclusion, we have identified two physically interacting proteins, Gpr1p and Plc1p, as novel components of a nitrogen signaling pathway controlling the developmental switch from yeast-like to pseudohyphal growth.	Nitrogen	113-121	phosphatidylinositol phospholipase C	Saccharomyces cerevisiae S288C	81-86
10454632-8	1999	Measurements of repair rates of nitrogen mustard N-alkylpurine adducts in the highly transcribed RPB2 gene demonstrate defects in the processing of mono-adducts in rad4, rad14 and mag1 strains.	Nitrogen	32-40	Rad4p	Saccharomyces cerevisiae S288C	164-168
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	Gat1p	Saccharomyces cerevisiae S288C	67-71
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	Gzf3p	Saccharomyces cerevisiae S288C	84-88
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	proteinase B	Saccharomyces cerevisiae S288C	115-119
10409709-0	1999	YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae.	Nitrogen	1-2	guanosine diphosphatase	Saccharomyces cerevisiae S288C	21-25
10467005-4	1999	While Gap1p and Agp1p appear to be the main cysteine transporters on the non-repressing nitrogen source proline, Bap2p, Bap3p, Tat1p, Tat2p, Agp1p and Gnp1p are all important for cysteine uptake on ammonium-based medium.	Nitrogen	88-96	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	16-21
10407265-4	1999	A nce103-Delta deletion strain did not grow on a rich peptone-yeast extract-glucose medium under normal aerobic conditions at pH values of 3.0-8.0, but grew like wild-type in an oxygen-free nitrogen or oxygen-reduced atmosphere over this pH range, and was more sensitive to H(2)O(2) than wild-type.	Nitrogen	190-198	carbonate dehydratase NCE103	Saccharomyces cerevisiae S288C	2-8
10364244-0	1999	Temporal association of the N- and O-linked glycosylation events and their implication in the polarized sorting of intestinal brush border sucrase-isomaltase, aminopeptidase N, and dipeptidyl peptidase IV.	Nitrogen	28-29	alanyl aminopeptidase, membrane	Homo sapiens	159-175
30139406-1	2018	Improving milk nitrogen efficiency through a reduction of CP supply without detrimental effect on productivity requires usage of feeding systems estimating both the flows of digestible protein, the exported true proteins and from these predict milk protein yield (MPY).	Nitrogen	15-23	PY	Bos taurus	244-262
10403632-9	1999	The above findings raise the possibility that a cytochrome P450-like protein, that can receive electrons from NADH, possibly through cytochrome b5 reductase, is present in the hepatic microsomes of rats and mice, and is capable of catalysing the bioactivation of aromatic amines through N-hydroxylation.	Nitrogen	110-111	cytochrome P450, family 4, subfamily v, polypeptide 3	Rattus norvegicus	48-76
30139406-1	2018	Improving milk nitrogen efficiency through a reduction of CP supply without detrimental effect on productivity requires usage of feeding systems estimating both the flows of digestible protein, the exported true proteins and from these predict milk protein yield (MPY).	Nitrogen	15-23	PY	Bos taurus	264-267
29711199-1	1999	A linear supramoleculecular array of anions and cations is present in the solvent-free potassium salt of the homoleptic erbium pyrazolate complex [K{Er(eta2 -tBu2 pz)4 }n ] (1).	Nitrogen	4-5	DNA polymerase iota	Homo sapiens	152-156
30453909-1	2018	BACKGROUND: This study aimed to explore hyper-O-linked N-acetylglucosaminylation (O-GlcNAcylation) with an elevation of the expression of O-linked-beta-N-acetylglucosamine transferase (OGT) in human bladder cancer.	Nitrogen	8-9	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	138-183
30453909-1	2018	BACKGROUND: This study aimed to explore hyper-O-linked N-acetylglucosaminylation (O-GlcNAcylation) with an elevation of the expression of O-linked-beta-N-acetylglucosamine transferase (OGT) in human bladder cancer.	Nitrogen	8-9	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	185-188
10353813-1	1999	A segment of complement receptor type 1 (CR1) corresponding to modules 15-17 was overexpressed as a functionally active recombinant protein with N-glycosylation sites ablated by mutagenesis (referred to as CR1 approximately 15-17(-)).	Nitrogen	145-146	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	13-39
30098555-2	2018	The CMCS simultaneously removes ammonia nitrogen (NH4+) and phosphate (PO43-) by chemical precipitation and it can achieve recovery of nitrogen and phosphorus.	Nitrogen	40-48	G protein signaling modulator 2	Homo sapiens	4-8
30098555-2	2018	The CMCS simultaneously removes ammonia nitrogen (NH4+) and phosphate (PO43-) by chemical precipitation and it can achieve recovery of nitrogen and phosphorus.	Nitrogen	135-143	G protein signaling modulator 2	Homo sapiens	4-8
10353813-1	1999	A segment of complement receptor type 1 (CR1) corresponding to modules 15-17 was overexpressed as a functionally active recombinant protein with N-glycosylation sites ablated by mutagenesis (referred to as CR1 approximately 15-17(-)).	Nitrogen	145-146	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	41-44
10336633-5	1999	Biosynthetic studies revealed that newly synthesized Xenopus Ac45 is an N-glycosylated protein of approximately 60 kDa; the nonglycosylated, newly synthesized form is approximately 46 kDa which is similar to the predicted size.	Nitrogen	72-73	ATPase, H+ transporting, lysosomal accessory protein 1, gene 1 S homeolog	Xenopus laevis	61-65
30419844-11	2018	Patients with higher N/LP ratio had an increased risk of developing postoperative AKI (6.36 +- 7.34 vs 4.33 +- 3.36, p < 0.001; unadjusted OR 1.1 (95% CI 1.04-1.16), p = 0.001; adjusted OR 1.05 (95% CI 1.00-1.10), p = 0.048).	Nitrogen	21-22	olfactory receptor family 4 subfamily F member 16	Homo sapiens	139-145
10336633-7	1999	We conclude that the regionally conserved Xenopus Ac45 protein is synthesized as an N-glycosylated approximately 60-kDa precursor that is intracellularly cleaved to an approximately 40-kDa product and speculate that it may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules.	Nitrogen	84-85	ATPase, H+ transporting, lysosomal accessory protein 1, gene 1 S homeolog	Xenopus laevis	50-54
30374089-6	2018	Our findings identified ORE1 as a downstream target of NLA/PHO2 (UBC24) and showed that post-translational regulation of ORE1 levels determines leaf senescence during nitrogen deficiency.	Nitrogen	167-175	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	55-58
29577547-1	2018	The plastidic glutamine synthetase isoform (GS2) plays a key role in nitrogen (N) assimilation.	Nitrogen	69-77	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	44-47
30012463-5	2018	Among the potential corresponding target mRNAs for the selected mature miRNAs, seven cell growth-related target genes (e2f2, akt2, mtor, bcl-2, bim, p38alpha, and bmf) and five N-glycosylation-related target genes (neu1, b4galt3, gale, man1b1 and mgat4a) were selected by considering the effectiveness of NaBu on rCHO cell culture.	Nitrogen	43-44	beta-1,4-galactosyltransferase 3	Rattus norvegicus	221-228
30012463-5	2018	Among the potential corresponding target mRNAs for the selected mature miRNAs, seven cell growth-related target genes (e2f2, akt2, mtor, bcl-2, bim, p38alpha, and bmf) and five N-glycosylation-related target genes (neu1, b4galt3, gale, man1b1 and mgat4a) were selected by considering the effectiveness of NaBu on rCHO cell culture.	Nitrogen	43-44	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Rattus norvegicus	247-253
30340381-8	2018	The adsorbents of Na-Cp and Ag-Cp showed good equilibrium selectivity for N2, and the equilibrium separation factors of N2 and CH4 were 7.25 and 6.53, respectively.	Nitrogen	74-76	synuclein alpha	Homo sapiens	18-23
30340381-9	2018	Consequently, the adsorbent of Na-Cp was suitable for nitrogen/methane mixture separation, which could make the concentration of methane concentrated from 19.7% to 30.72%.	Nitrogen	54-62	synuclein alpha	Homo sapiens	31-36
30252493-1	2018	A range of ortho-pi-extended PDI derivatives are straightforwardly synthesized in good yields through highly regioselective heteroannulations of ortho-alkynyl-substituted PDI derivatives with sulfur, selenium, or nitrogen nucleophiles.	Nitrogen	213-221	peptidyl arginine deiminase 1	Homo sapiens	29-32
30252493-1	2018	A range of ortho-pi-extended PDI derivatives are straightforwardly synthesized in good yields through highly regioselective heteroannulations of ortho-alkynyl-substituted PDI derivatives with sulfur, selenium, or nitrogen nucleophiles.	Nitrogen	213-221	peptidyl arginine deiminase 1	Homo sapiens	171-174
10235685-1	1999	The human nerve growth factor receptor (TrkA) contains four potential N-glycosylation sites that are highly conserved within the Trk family of neurotrophin receptors, and nine additional sites that are less well conserved.	Nitrogen	70-71	neurotrophic receptor tyrosine kinase 1	Homo sapiens	40-44
29864684-4	2018	The active compounds formed hydrogen bond at DHFR binding site between N1-nitrogen of the pyridazine ring with Glu30; the carbonyl group with Trp24, Arg70 or Lys64; pi-cation interaction with Arg22 and pi-pi interaction with Phe31 residues.	Nitrogen	74-82	dihydrofolate reductase	Homo sapiens	45-49
30087118-1	2018	N-Formylation of the Met-tRNAMet by the nuclearly encoded mitochondrial methionyl-tRNA formyltransferase (MTFMT) has been found to be a key determinant of protein synthesis initiation in mitochondria.	Nitrogen	0-1	mitochondrial methionyl-tRNA formyltransferase	Homo sapiens	72-104
30087118-1	2018	N-Formylation of the Met-tRNAMet by the nuclearly encoded mitochondrial methionyl-tRNA formyltransferase (MTFMT) has been found to be a key determinant of protein synthesis initiation in mitochondria.	Nitrogen	0-1	mitochondrial methionyl-tRNA formyltransferase	Homo sapiens	106-111
10235685-1	1999	The human nerve growth factor receptor (TrkA) contains four potential N-glycosylation sites that are highly conserved within the Trk family of neurotrophin receptors, and nine additional sites that are less well conserved.	Nitrogen	70-71	neurotrophic receptor tyrosine kinase 1	Homo sapiens	40-43
30280025-6	2018	Results indicated that soil total nitrogen (STN) was affected by tree stem density adjustments in the short-term; STN generally increased with decreasing tree stem density, reaching its highest concentration in the MT treatment before decreasing in HT.	Nitrogen	34-42	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	44-47
10235685-2	1999	Using a microscale deglycosylation assay, we show here that both conserved and variable N-glycosylation sites are used during maturation of TrkA.	Nitrogen	88-89	neurotrophic receptor tyrosine kinase 1	Homo sapiens	140-144
29981898-5	2018	Using an off-line HPLC-MALDI-TOF-MS approach combined with exoglycosidase digestions and MS/MS, we reveal that the multiple hexose residues of the N-glycans of the gly-12;gly-13;gly-14 triple mutant are not just mannose, but include galactoses in three different positions (beta-intersecting, beta-bisecting and alpha-terminal) on isomeric forms of Hex4-8HexNAc2 structures; some of these structures are fucosylated and/or methylated.	Nitrogen	147-148	GLYcosylation related	Caenorhabditis elegans	178-184
10229237-3	1999	Because the asialoglycoprotein (ASGP) receptor is specifically expressed in the liver at high density, the ASGP receptor-binding domain was generated within an N-glycosylated human IFN-beta molecule by the removal of sialic acid to direct this cytokine to the liver.	Nitrogen	160-161	interferon beta 1	Homo sapiens	181-189
30097366-0	2018	Design, synthesis and biological evaluation of a series of novel GPR40 agonists containing nitrogen heterocyclic rings.	Nitrogen	91-99	free fatty acid receptor 1	Mus musculus	65-70
30097366-1	2018	A novel series of GPR40 agonists is designed by introducing nitrogen-containing heterocyclic ring at the terminal phenyl ring of TAK-875 with the aim of decreasing its lipophilicity.	Nitrogen	60-68	free fatty acid receptor 1	Mus musculus	18-23
30209482-0	2018	tert-Butyl nitrite mediated nitrogen transfer reactions: synthesis of benzotriazoles and azides at room temperature.	Nitrogen	28-36	telomerase reverse transcriptase	Homo sapiens	0-4
10227578-1	1999	Nitrogen mustard (bis(2-chloroethyl) methylamine, HN2) inhibited the binding of upstream factors Sp1 and AP2 to their consensus sequences.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	50-53
30063822-5	2018	To illustrate the procedure, we have made an application to a two-domain construct of Robo1, a protein that carries a single N-glycosylation site in its N-terminal domains.	Nitrogen	125-126	roundabout guidance receptor 1	Homo sapiens	86-91
30045842-1	2018	The mitochondrial amidoxime reducing component is a recently discovered molybdenum enzyme in mammals which, in concert with the electron transport proteins cytochrome b5 and NADH cytochrome b5 reductase, catalyzes the reduction of N-oxygenated structures.	Nitrogen	174-175	cytochrome b5 type A	Homo sapiens	156-169
30045842-1	2018	The mitochondrial amidoxime reducing component is a recently discovered molybdenum enzyme in mammals which, in concert with the electron transport proteins cytochrome b5 and NADH cytochrome b5 reductase, catalyzes the reduction of N-oxygenated structures.	Nitrogen	174-175	cytochrome b5 type A	Homo sapiens	179-192
10102990-5	1999	The essential three amino acids in the active site triad, His, Asp, and Ser, and the single putative N-glycosylation site were conserved in human and mouse neuropsin.	Nitrogen	101-102	opsin 5	Mus musculus	156-165
30129677-6	2018	Knock-out of MtCDPK5 in nad1-1 mutant plants partially restored nitrogen-fixing nodules.	Nitrogen	64-72	NADH dehydrogenase subunit 1	Medicago truncatula	24-28
30181269-0	2018	Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis.	Nitrogen	55-56	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	10-17
30181269-2	2018	Mammals have OST isoforms with STT3A or STT3B catalytic subunits for cotranslational or posttranslational N-glycosylation, respectively.	Nitrogen	106-107	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	31-36
30181269-2	2018	Mammals have OST isoforms with STT3A or STT3B catalytic subunits for cotranslational or posttranslational N-glycosylation, respectively.	Nitrogen	106-107	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	40-45
30181269-13	2018	Without strict kinetic limitations during posttranslational N-glycosylation, STT3B-OST can thus moonlight for LLO hydrolysis.	Nitrogen	60-61	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	77-82
30181269-14	2018	In contrast, the STT3A-OST/translocon complex preserves LLOs for temporally fastidious cotranslational N-glycosylation.	Nitrogen	103-104	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	17-22
29939350-1	2018	Lowering the CP level in piglet diets reduces the risk of postweaning diarrhea and N excretion to the environment.	Nitrogen	83-84	ceruloplasmin	Homo sapiens	13-15
30049229-0	2018	Highly selective N-glucuronidation of four piperazine-containing drugs by UDP-glucuronosyltransferase 2B10.	Nitrogen	17-18	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	74-106
30049229-5	2018	Reaction phenotyping, chemical inhibition, and activity correlation analysis revealed that UGT2B10 was a high-affinity enzyme and mainly responsible for hepatic N-glucuronidation of all drugs except mianserin.	Nitrogen	161-162	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	91-98
30049229-9	2018	CONCLUSIONS: UGT2B10 plays a critical role in N-glucuronidation of piperazine-containing drugs.	Nitrogen	2-3	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	13-20
30125302-3	2018	In HEK-293 and MDCK cells constitutively expressing CRB2, we found that the protein localized to the apicolateral side of the cell plasma membrane and that this plasma membrane assembly required N-glycosylation.	Nitrogen	195-196	protein crumbs homolog 2	Canis lupus familiaris	52-56
29717387-0	2018	beta4GalT1 Mediates PPARgamma N-Glycosylation to Attenuate Microglia Inflammatory Activation.	Nitrogen	30-31	beta-1,4-galactosyltransferase 1	Homo sapiens	0-10
9891035-6	1999	Induction of AGP1 requires Uga35p(Dal81p/DurLp), a transcription factor of the Cys6-Zn2 family previously shown to participate in several nitrogen induction pathways.	Nitrogen	138-146	amino acid transporter AGP1	Saccharomyces cerevisiae S288C	13-17
29901386-2	2018	In this work, a simple one-pot template-free strategy for the preparation of three-dimensional hierarchical porous nitrogen-doped carbon framework in situ armored NiO nanograins (NCF/NiO) by an ammonia-induced method assisted by the pyrolysis of a decomposable salt is reported.	Nitrogen	115-123	neutrophil cytosolic factor 4	Homo sapiens	179-182
30017230-3	2018	The present study demonstrates that treatment of cultured mouse cortical astrocytes for 24 h with 5 mM ammonium chloride ("ammonia") inhibits the system N-mediated L-glutamine transport out of the cell, and that this inhibition is related to the reduced presence of the SN1 transporter on the cell membrane.	Nitrogen	153-154	solute carrier family 38, member 3	Mus musculus	270-273
10078836-6	1999	Hydroxylation and N-demethylation accounted for most of the CSA metabolized in all the species tested.	Nitrogen	18-19	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	60-63
30040391-6	2018	Further reduction of the Co(I) complex was found to generate a pincer-based pi-radical anion that demonstrated well-resolved EPR features to the four hydrogen atoms and lone nitrogen atom of the ligand with minor contributions from cobalt and coordinated N2.	Nitrogen	174-182	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	25-30
30040391-6	2018	Further reduction of the Co(I) complex was found to generate a pincer-based pi-radical anion that demonstrated well-resolved EPR features to the four hydrogen atoms and lone nitrogen atom of the ligand with minor contributions from cobalt and coordinated N2.	Nitrogen	255-257	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	25-30
30022665-4	2018	We find that helix propensity is influenced by side chain placement within the beta residue [beta3 (side chain adjacent to nitrogen) slightly favored relative to beta2 (side chain adjacent to carbonyl)].	Nitrogen	123-131	basic helix-loop-helix family member e22	Homo sapiens	93-98
29774606-0	2018	Nitrogen-Doped CoP Electrocatalysts for Coupled Hydrogen Evolution and Sulfur Generation with Low Energy Consumption.	Nitrogen	0-8	caspase recruitment domain family member 16	Homo sapiens	15-18
29774606-4	2018	Nitrogen doping lowers the d-band of CoP and weakens the H adsorption on the surface of CoP because of the strong electronegativity of nitrogen as compared to phosphorus.	Nitrogen	0-8	caspase recruitment domain family member 16	Homo sapiens	37-40
29774606-4	2018	Nitrogen doping lowers the d-band of CoP and weakens the H adsorption on the surface of CoP because of the strong electronegativity of nitrogen as compared to phosphorus.	Nitrogen	0-8	caspase recruitment domain family member 16	Homo sapiens	88-91
29774606-4	2018	Nitrogen doping lowers the d-band of CoP and weakens the H adsorption on the surface of CoP because of the strong electronegativity of nitrogen as compared to phosphorus.	Nitrogen	135-143	caspase recruitment domain family member 16	Homo sapiens	88-91
9804831-2	1998	FMO2, or "pulmonary" FMO, one of five forms of the enzyme identified in mammals, is expressed predominantly in lung and differs from other FMOs in that it can catalyze the N-oxidation of certain primary alkylamines.	Nitrogen	172-173	flavin containing dimethylaniline monoxygenase 2	Homo sapiens	0-4
29718568-0	2018	An Exceptionally Efficient Co-Co2 P@N, P-Codoped Carbon Hybrid Catalyst for Visible Light-Driven CO2 -to-CO Conversion.	Nitrogen	36-37	complement C2	Homo sapiens	30-33
29621646-3	2018	Modified glassy carbon electrode of N-CQD/Cu2O/GCE is developed and is used for the sensor studies of aspirin.	Nitrogen	36-37	guanylate cyclase 2E, pseudogene	Homo sapiens	47-50
9881155-8	1998	Moreover, the levels of ASN2 and ASN1 mRNA are also reciprocally regulated by carbon and nitrogen metabolites.	Nitrogen	89-97	asparagine synthetase 2	Arabidopsis thaliana	24-28
29949175-8	2018	RESULTS: Renal function indexes such as urinary protein, creatinine, blood urea nitrogen, and glomerular filtration rate (GFR) were significantly higher with SGLT-2 inhibitor treatment compared with the control group (p&lt;0.05).	Nitrogen	80-88	solute carrier family 5 member 2	Homo sapiens	158-164
29741700-9	2018	These results confirm that a reduced dietary N intake led to decreased TRPV5, CaBPD28K, PTHR, and NCX1 expression levels, contributing to low levels of calcitriol and plasma Ca.	Nitrogen	45-46	transient receptor potential cation channel subfamily V member 5	Capra hircus	71-76
9881155-9	1998	The distinct regulation of ASN1 and ASN2 genes combined with their distinct encoded isoenzymes suggest that they may play different roles in nitrogen metabolism, as discussed in this paper.	Nitrogen	141-149	asparagine synthetase 2	Arabidopsis thaliana	36-40
9774483-11	1998	These results suggest that polysialylation of NCAM is influenced by the difference between PST and STX in their preference for N-glycosylation sites on NCAM.	Nitrogen	46-47	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	91-94
29362985-6	2018	The growth of tumors in the treated groups was assessed by histological changes and the up/down expression of p53, cdkn1, cdk2, e-cdh, and n-cdh genes in different parts of GI tract.	Nitrogen	22-23	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	110-113
30056511-0	2018	Carbon dots doped with nitrogen and boron as ultrasensitive fluorescent probes for determination of alpha-glucosidase activity and its inhibitors in water samples and living cells.	Nitrogen	23-31	sucrase-isomaltase	Homo sapiens	100-117
29993059-2	2018	Many complexes of the type BMX, (where B is a Lewis base such as H2, N2, ethyne, ethene, cyclopropane, H2O, H2S, PH3, or NH3, M is a coinage-metal atom Cu, Ag or Au, and X is a halogen atom) have now been characterised in the gas phase through their rotational spectra.	Nitrogen	69-71	BMX non-receptor tyrosine kinase	Homo sapiens	27-30
29577899-7	2018	N-glycosylation of alphavbeta3 and alphavbeta6 integrins is required for the attachment of cells to ECM proteins like fibronectin.	Nitrogen	0-1	multimerin 1	Homo sapiens	100-103
29577899-10	2018	The investigation typify that N-glycosylation on integrins is also necessary for cell-ECM interaction.	Nitrogen	30-31	multimerin 1	Homo sapiens	86-89
9824232-1	1998	Nitrogen mustard (HN2) is a bifunctional alkylating agent which is thought to cause cytotoxicity by covalently binding to DNA.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	18-21
29767695-9	2018	Finally, mARC, discovered less than a decade ago, works in concert with cytochrome b5 type B and NAD(H) cytochrome b5 reductase to reduce a variety of N-hydroxylated substrates, although the physiologic significance is still unclear.	Nitrogen	97-98	activity regulated cytoskeletal-associated protein	Mus musculus	9-13
29717117-8	2018	Inhibition of N-glycosylation did not alter cell surface expression of mTRAIL-R but enhanced its ability to bind TRAIL, and facilitated mTRAIL-R oligomerization, which resulted in enhanced death-inducing signaling complex (DISC) formation and caspase-8 activation.	Nitrogen	14-15	caspase 8	Mus musculus	243-252
30006522-4	2018	The results show that the proposed FeN2 stabilizes by a break up of molecule N2 into a novel planar N4 unit (P63/mcm, &gt;228 GPa) while FeN4 stabilizes by a infinite 1D linear nitrogen chains N  (P-1, &gt;50 GPa; Cmmm, &gt;250 GPa).	Nitrogen	37-39	tumor protein p63	Homo sapiens	109-116
29770942-0	2018	Facile preparation of nitrogen and sulfur co-doped graphene-based aerogel for simultaneous removal of Cd2+ and organic dyes.	Nitrogen	22-30	CD2 molecule	Homo sapiens	102-105
9726238-5	1998	Hypoxia (0.5% O2, 5% CO2, and 94.5% N2) stimulated GLUT1 mRNA expression in BRECs in a time-dependent manner with an 8.9 +/- 1.5-fold (P &lt; 0.01) increase observed after 12 h. GLUT1 mRNA expression returned to baseline (1.4 +/- 0.3-fold of control) within 12 h after reinstitution of normoxia.	Nitrogen	36-38	solute carrier family 2 member 1	Bos taurus	51-56
29770942-2	2018	A nitrogen (N) and sulfur (S) co-doped graphene-based aerogel (GBA) modified with 2,5-dithiobisurea was synthesized hydrothermally for simultaneous adsorption of Cd2+ and organic dyes-safranin-O (SO), crystal violet (CV), and methylene blue (MB).	Nitrogen	2-10	CD2 molecule	Homo sapiens	162-165
29915530-0	2018	N-Glycosylation Regulates the Trafficking and Surface Mobility of GluN3A-Containing NMDA Receptors.	Nitrogen	0-1	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	66-72
29710432-2	2018	Using permeabilized recombinant fission yeast cells (enzyme bags), we demonstrate that UGT1A5 can catalyze an N-glucuronidation reaction.	Nitrogen	110-111	UDP glucuronosyltransferase family 1 member A5	Homo sapiens	87-93
29718541-6	2018	Both participate in Nox1 trafficking, as Nox1 advances to the cell surface in two differentially N-glycosylated forms, one complex and one high mannose, in a Sar1/Stx5-dependent and -independent manner, respectively.	Nitrogen	20-21	secretion associated Ras related GTPase 1A	Homo sapiens	158-162
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Nitrogen	0-1	secretion associated Ras related GTPase 1A	Homo sapiens	133-137
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Nitrogen	0-1	NADPH oxidase 5	Homo sapiens	171-175
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Nitrogen	0-1	secretion associated Ras related GTPase 1A	Homo sapiens	235-239
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Nitrogen	0-1	secretion associated Ras related GTPase 1A	Homo sapiens	235-239
29498046-3	2018	Through bioinformatics analyses, we determined that among plant protein kinase families, the occurrence of motifs indicative for dual lipidation by N-myristoylation and S-acylation is restricted to only five kinase families, including the Ca2+ -regulated CDPK-SnRK and CBL protein families.	Nitrogen	148-149	Cbl proto-oncogene	Homo sapiens	269-272
29414081-4	2018	Then, CdS nanoparticles further were modified by in-situ growth method to form Zn2SnO4/N,S-GQDs/CdS composite with prominent photocurrent, which was 30 times that of the Zn2SnO4 cube alone.	Nitrogen	87-88	CDP-diacylglycerol synthase 1	Homo sapiens	6-9
29414081-4	2018	Then, CdS nanoparticles further were modified by in-situ growth method to form Zn2SnO4/N,S-GQDs/CdS composite with prominent photocurrent, which was 30 times that of the Zn2SnO4 cube alone.	Nitrogen	87-88	CDP-diacylglycerol synthase 1	Homo sapiens	96-99
29719149-1	2018	Among the many metal-dinitrogen complexes synthesized, the end-on bridging (mu2, eta1, eta1-N2) coordination mode is notoriously unreactive for nitrogen fixation.	Nitrogen	21-31	secreted phosphoprotein 1	Homo sapiens	81-85
29719149-1	2018	Among the many metal-dinitrogen complexes synthesized, the end-on bridging (mu2, eta1, eta1-N2) coordination mode is notoriously unreactive for nitrogen fixation.	Nitrogen	21-31	secreted phosphoprotein 1	Homo sapiens	87-91
29719149-1	2018	Among the many metal-dinitrogen complexes synthesized, the end-on bridging (mu2, eta1, eta1-N2) coordination mode is notoriously unreactive for nitrogen fixation.	Nitrogen	23-31	secreted phosphoprotein 1	Homo sapiens	81-85
29719149-1	2018	Among the many metal-dinitrogen complexes synthesized, the end-on bridging (mu2, eta1, eta1-N2) coordination mode is notoriously unreactive for nitrogen fixation.	Nitrogen	23-31	secreted phosphoprotein 1	Homo sapiens	87-91
29783634-4	2018	Molecular modeling studies confirmed a consolidated binding mode in which the nitrogen of the imidazolyl moiety coordinated the heme ferrous iron, meanwhile the hydrophobic groups were located in the western region of HO-1 binding pocket.	Nitrogen	78-86	heme oxygenase 1	Homo sapiens	218-222
29412948-3	2018	Owing to the unique structure and properties originating from the enhanced surface area, nitrogen functional groups and defects introduced on both the basal and edges, N2/Ar/GS/GNR/GCE showed high electrocatalytic activity for the electrochemical oxidations of AA, DA, and UA with the respective lowest detection limits of 5.3, 2.5 and 5.7 nM and peak-to-peak separation potential (DeltaEP) (vs Ag/AgCl) in DPV of 220, 152 and 372 mV for AA/DA, DA/UA and AA/UA respectively.	Nitrogen	89-97	guanylate cyclase 2E, pseudogene	Homo sapiens	168-184
29438977-1	2018	The detoxification enzyme UDP-glucuronosyltransferase UGT2B10 is specialized in the N-linked glucuronidation of many drugs and xenobiotics.	Nitrogen	84-85	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	54-61
29596975-5	2018	CYP2C9 played an exclusive role in n-butyl hydroxylation.	Nitrogen	15-16	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	0-6
29443459-3	2018	Herein, the comprehensive development of manganese cobalt oxide/nitrogen-doped multiwalled carbon nanotube hybrids (Mnx Co3-x O4 @NCNTs) is reported for highly reversible oxygen reduction and evolution reactions (ORR and OER, respectively).	Nitrogen	64-72	keratin 86	Homo sapiens	116-119
29645054-3	2018	To increase the stability of the ArSb complexes, in particular those containing Pd(ii), the simple auxiliary ligands were replaced with C,N-chelating ones, which led to a set of four compounds of the type [RMCl(ArSb)], where R = C6H4-2-(CH2NMe2) or Fe(eta5-C5H4)(eta5-C5H3-2-(CH2NMe2)) and M = Pd (3, 5) or Pt (4, 6).	Nitrogen	138-139	arylsulfatase B	Homo sapiens	33-37
29636091-8	2018	Bach1-deficient MRL/lpr mice exhibited increased HO-1 expression in kidneys, prolonged survival, reduced urine proteins, and serum blood urea nitrogen levels, but serum anti-dsDNA antibody levels were comparable.	Nitrogen	142-150	BTB and CNC homology 1, basic leucine zipper transcription factor 1	Mus musculus	0-5
29636521-3	2018	The comparison of PR1 and PR2 pocket properties showed that bound PR2 pockets were more hydrophobic with more oxygen atoms and fewer nitrogen atoms than PR1 pockets.	Nitrogen	133-141	transmembrane protein 37	Homo sapiens	18-21
29424476-2	2018	This approach provides a unique methodology involving a site-selective C-N bond formation for preparation of C-2 substituted nitro indoles.	Nitrogen	73-74	complement C2	Homo sapiens	109-112
29442311-3	2018	Adding H2O decreased the possibility of reactions between the reductive groups (NH) and the oxygen radical during devolatilization, which led to a decrease in NO emissions at 1000  C. However, as the furnace temperature increased, "additional" nitrogen precursors (HCN and NH3) generated by enhanced char-H2O gasification were quickly oxidized to generate a large amount of NO during char oxidation that exceeded the amount of NO reduced by NH during devolatilization.	Nitrogen	244-252	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	265-268
29411222-7	2018	N-Glycopeptide analysis with UHPLC-QTOF-MSE confirmed the N-glycosylation sites (N149, N171 and N317) as well as Fc-specific glycosylation on N317, and TNFR-specific highly sialylated glycans on N149 and N171 on both investigated products.	Nitrogen	0-1	TNF receptor superfamily member 1A	Homo sapiens	152-156
29425399-4	2018	Herein, we demonstrate nitrogen atom transfer (NAT) from a lattice-confined Ru2 nitride to toluene to generate benzylamine.	Nitrogen	23-31	doublecortin domain containing 2	Homo sapiens	76-79
29336543-2	2018	Here, we report in vitro profiling of HDAC11 deacylase activities, and our data unequivocally show that the enzyme efficiently removes acyl moieties spanning 8-18 carbons from the side chain nitrogen of the lysine residue of a peptidic substrate.	Nitrogen	191-199	histone deacetylase 11	Homo sapiens	38-44
29053817-8	2018	Moreover, we found that concanamycin A treatment prevented the degradation of ribosomal proteins RPS6 and RPL37 under nitrogen or phosphate deprivation.	Nitrogen	118-126	ribosomal protein S6	Chlamydomonas reinhardtii	97-101
29498673-4	2018	Remarkably, though, despite the fact that all membrane-bound TRAIL receptors harbor putative glycosylation sites, only pro-apoptotic signaling through DR4 and DR5 has, so far, been found to be regulated by N- and O-glycosylation, respectively.	Nitrogen	206-207	TNF receptor superfamily member 10b	Homo sapiens	159-162
29323465-3	2018	Time course induction of ER stress, using tunicamycin (TM), shows a group of genes such as Chop, Trb3, Sqstm1, Grp78, and Herpud1 respond rapidly to TM inhibition of N-glycosylation, while others such as Atf5, Odz4, and Birc5 exhibits a delayed response.	Nitrogen	166-167	homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein	Cricetulus griseus	122-129
29323465-3	2018	Time course induction of ER stress, using tunicamycin (TM), shows a group of genes such as Chop, Trb3, Sqstm1, Grp78, and Herpud1 respond rapidly to TM inhibition of N-glycosylation, while others such as Atf5, Odz4, and Birc5 exhibits a delayed response.	Nitrogen	166-167	cyclic AMP-dependent transcription factor ATF-5	Cricetulus griseus	204-208
29621420-2	2018	We previously showed that deletion of endothelial N-acetylglucosamine N-deacetylase-N-sulfotransferase-1 (Ndst1), an enzyme responsible for N-sulfation during HS biosynthesis, reduces allergic airway inflammation (AAI).	Nitrogen	50-51	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	Mus musculus	70-104
29621420-2	2018	We previously showed that deletion of endothelial N-acetylglucosamine N-deacetylase-N-sulfotransferase-1 (Ndst1), an enzyme responsible for N-sulfation during HS biosynthesis, reduces allergic airway inflammation (AAI).	Nitrogen	50-51	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	Mus musculus	106-111
29282902-0	2018	Construction of green fluorescence protein mutant to monitor STT3B-dependent N-glycosylation.	Nitrogen	77-78	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	61-66
29282902-5	2018	Here, we describe mutant constructs of monomeric enhanced green fluorescent protein (mEGFP), which are susceptible to STT3B-dependent N-glycosylation.	Nitrogen	134-135	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	118-123
29282902-9	2018	Our results suggest that the mutant ER-mEGFP is useful for monitoring STT3B-dependent post-translocational N-glycosylation in cells of interest, such as those from putative patients with a congenital disorder of glycosylation.	Nitrogen	107-108	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	70-75
28782088-6	2018	Previous studies implicated that N-linked glycosylation is crucial for plasma membrane targeting and ligand binding of human NKp30.	Nitrogen	33-34	natural cytotoxicity triggering receptor 3	Homo sapiens	125-130
28782088-7	2018	However, even though present in all other jawed vertebrates analyzed so far, these three N-linked glycosylation sites are missing in mouse NKp30.	Nitrogen	89-90	natural cytotoxicity triggering receptor 3	Homo sapiens	139-144
29356313-3	2018	Herein, a general approach for the production of 1D porous nitrogen-doped graphitic carbon fibers embedded with active ORR components, (M/MOx , i.e., metal or metal oxide nanoparticles) using a facile two-step electrospinning and annealing process is reported.	Nitrogen	59-67	monooxygenase DBH like 1	Homo sapiens	138-141
29065215-7	2018	Gene expression experiments showed that, apart from the conventional nitrogen catabolic repression mechanism that is operating in aerobiosis, there seems to be an oxygen-independent mechanism acting to overexpress key genes like GAP1, GDH1, GDH2 and GLT1 to ensure adequate anaerobic growth even in the presence of non-preferential nitrogen source.	Nitrogen	332-340	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	235-239
29495785-0	2018	Kinetics of CO+ and CO2+ with N and O atoms.	Nitrogen	30-31	complement C2	Homo sapiens	20-23
29495785-1	2018	We have measured reaction rate constants for CO+ and CO2+ reacting with N and O atoms using a selected ion flow tube apparatus equipped with a microwave discharge atom source.	Nitrogen	72-73	complement C2	Homo sapiens	53-56
29495785-4	2018	We report room-temperature rate constants of 1.0 +- 0.4 x 10-11 cm3 s-1 and 4.0 +- 1.6 x 10-11 cm3 s-1 for the reactions of CO+ with N and O atoms, respectively, and 8.0 +- 3.0 x 10-12 cm3 s-1 and 2.0 +- 0.8 x 10-11 cm3 s-1 for the reactions of CO2+ with N and O atoms, respectively.	Nitrogen	133-134	complement C2	Homo sapiens	245-248
29346724-5	2018	In this work, human lumenal N-glycosylated EXTL3 (EXTL3DeltaN) was cloned, expressed in human embryonic kidney cells, and purified.	Nitrogen	28-29	exostosin like glycosyltransferase 3	Homo sapiens	43-48
29346724-5	2018	In this work, human lumenal N-glycosylated EXTL3 (EXTL3DeltaN) was cloned, expressed in human embryonic kidney cells, and purified.	Nitrogen	28-29	exostosin like glycosyltransferase 3	Homo sapiens	50-61
29520285-11	2018	Thus, GS2 has a central role as a regulator between the nitrogen and the carbon cycles via maintaining glutamine-glutamate pool in the chloroplast on the level of substrates, in addition to its function in ammonia assimilation.	Nitrogen	56-64	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	6-9
29212317-5	2018	Here, we profile the O- and N-linked glycosylation of HDL associated-proteins including the truncated form of Apo CIII and their glycan heterogeneity in a site-specific manner.	Nitrogen	28-29	apolipoprotein C3	Homo sapiens	110-118
29043425-11	2018	These results provide the first documentation that NAT1-catalyzed N-acetylation in PBMC is higher in T cell than in other immune cell subtypes and that individual variation in N-acetylation capacity is dependent upon NAT1 mRNA and NAT1 haplotype.	Nitrogen	51-52	N-acetyltransferase 1	Homo sapiens	217-221
29662028-4	2018	Here, we show that the subcellular localization of NRs is modulated by the E3 SUMO (Small ubiquitin-related modifier) ligase AtSIZ1 and that NR protein levels are regulated by nitrogen sources.	Nitrogen	176-184	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	125-131
29563355-0	2018	Ultrasonic Mist Generation Assist Argon-Nitrogen Mix Gas Effect on Radioactive Strontium Quantification by Online Solid-Phase Extraction with Inductively Coupled Plasma Mass Spectrometry.	Nitrogen	40-48	Mix paired-like homeobox	Homo sapiens	49-52
29563355-3	2018	An ultrasonic nebulizer (USN) improved the Ar-N2 mixture gases effect of Sr and the mix gases (with USN) enhanced 3.7-times the signal intensity of Sr in normal pure Ar gas (with USN) in an online SPE-ICPMS.	Nitrogen	46-48	Mix paired-like homeobox	Homo sapiens	49-52
28857264-1	2018	The N   B triel bonds in complexes of boron trihalides, BX3 (X = F, Cl, Br, and I), with species acting as Lewis bases through the nitrogen center, NH3 , N2 , and HCN, are analyzed theoretically (MP2/aug-cc-pVTZ calculations).	Nitrogen	131-139	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	163-166
28857264-2	2018	It is confirmed that stronger Lewis acid properties of the boron center are observed for the BCl3 moiety than for the BF3 one in complexes with the strong Lewis base (NH3 ); while the opposite order is observed for complexes with the weak Lewis base (N2 ).	Nitrogen	251-253	BCL3 transcription coactivator	Homo sapiens	93-97
29915518-0	2018	Conformational Landscapes of Ubiquitin, Cytochrome c, and Myoglobin: Uniform Field Ion Mobility Measurements in Helium and Nitrogen Drift Gas.	Nitrogen	123-131	myoglobin	Homo sapiens	58-67
29272560-2	2018	Two classes of beta residue have been widely explored in the context of generating alpha-helix-like conformations: beta3 -amino acids, which are homologous to alpha-amino acids and bear a side chain on the backbone carbon adjacent to nitrogen, and residues constrained by a five-membered ring, such the one derived from trans-2-aminocyclopentanecarboxylic acid (ACPC).	Nitrogen	234-242	basic helix-loop-helix family member e22	Homo sapiens	115-120
29540735-0	2018	Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation.	Nitrogen	36-37	adhesion G protein-coupled receptor E2	Homo sapiens	24-28
29540735-0	2018	Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation.	Nitrogen	36-37	adhesion G protein-coupled receptor E2	Homo sapiens	29-35
29540735-5	2018	Herein, the membrane-associated NTF of EMR2/ADGRE2 is investigated and found to be modified by differential N-glycosylation.	Nitrogen	32-33	adhesion G protein-coupled receptor E2	Homo sapiens	39-43
29540735-5	2018	Herein, the membrane-associated NTF of EMR2/ADGRE2 is investigated and found to be modified by differential N-glycosylation.	Nitrogen	32-33	adhesion G protein-coupled receptor E2	Homo sapiens	44-50
29540735-6	2018	The membrane association of EMR2-NTF occurs in post-ER compartments and site-specific N-glycosylation in the GAIN domain is involved in modulating its membrane-association ability.	Nitrogen	33-34	adhesion G protein-coupled receptor E2	Homo sapiens	28-32
29341380-2	2018	A Mott-Schottky catalyst composed of Ni nanoparticles and tailorable nitrogen-doped carbon-foam (Ni/NCF) and thus tunable adsorption energy is presented for highly efficient and selective dehydrogenation of gas-phase methanol to hydrogen and CO even under relatively high weight hourly space velocities (WHSV).	Nitrogen	69-77	neutrophil cytosolic factor 4	Homo sapiens	100-103
29241623-5	2018	In IL-36R knockout mice, plasma creatinine, blood urea nitrogen, and IL-6 levels after ischemia-reperfusion injury were significantly lower than those in wild-type mice.	Nitrogen	55-63	interleukin 1 receptor-like 2	Mus musculus	3-9
29373725-1	2018	Ammonium is a major nitrogen source for plants; it is assimilated into glutamine via a reaction catalyzed by glutamine synthetase (GLN).	Nitrogen	20-28	hypothetical protein	Arabidopsis thaliana	109-129
29373725-1	2018	Ammonium is a major nitrogen source for plants; it is assimilated into glutamine via a reaction catalyzed by glutamine synthetase (GLN).	Nitrogen	20-28	hypothetical protein	Arabidopsis thaliana	131-134
29363704-3	2018	In this study, through mass spectroscopy-based N-glycoproteomics, we analyzed protein glycosylation of human MFGM.	Nitrogen	47-48	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	109-113
29363704-4	2018	A total of 912 N-glycosylation sites on 506 N-glycoproteins were identified in human colostrum and mature milk MFGM.	Nitrogen	15-16	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	111-115
29363704-5	2018	Among them, 220 N-glycoproteins with 304 N-glycosylation sites were differentially expressed in colostrum and mature milk MFGM.	Nitrogen	16-17	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	122-126
29363704-9	2018	Our results provide an in-depth understanding of the quantitative changes in N-glycosylation of proteins in human colostrum and mature MFGM, and extend our knowledge of the N-glycoproteome and of the distribution of N-glycosylation sites in human MFGM during lactation, providing insight into the biological functions of the highlighted glycoproteins.	Nitrogen	77-78	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	135-139
29531809-10	2018	The selective inhibition of nuNCX1 by XIP-NLS increased the percentage of beta III tubulin-positive immature neurons in mature cultures of MAP-2-positive cortical neurons, thus unraveling a new function for nuNCX1 in regulating neuronal differentiation through [Ca2+]n-dependent PTEN/PI3K/Akt pathway.	Nitrogen	15-16	phosphatase and tensin homolog	Homo sapiens	279-283
29187599-2	2018	Human diamine oxidase (hDAO), required for histamine catabolism, has multiple N-glycosylation sites, but their roles, for example in DAO secretion, are unclear.	Nitrogen	78-79	D-amino acid oxidase	Homo sapiens	24-27
29441948-8	2018	Renal cells with upregulated miR-146 had lower plasma levels of blood urea nitrogen (BUN) and creatinine, decreased apoptosis and active caspase-3 protein expressions.	Nitrogen	75-83	microRNA 146	Mus musculus	29-36
29607936-9	2018	Moreover, we found that STT3B-dependent posttranslational N-glycosylation at N98 residue occurred in G101S TTR but not in other TTR variants, possibly due to amino acid alterations that increase N-glycosylation preference or accelerate rigid structure formation susceptible to N-glycosylation.	Nitrogen	77-78	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	24-29
29607936-9	2018	Moreover, we found that STT3B-dependent posttranslational N-glycosylation at N98 residue occurred in G101S TTR but not in other TTR variants, possibly due to amino acid alterations that increase N-glycosylation preference or accelerate rigid structure formation susceptible to N-glycosylation.	Nitrogen	77-78	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	24-29
29113979-1	2018	Gln3 is responsible for Nitrogen Catabolite Repression-sensitive transcriptional activation in the yeast Saccharomyces cerevisiae In nitrogen-replete medium, Gln3 is cytoplasmic and NCR-sensitive transcription is repressed.	Nitrogen	24-32	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
29113979-1	2018	Gln3 is responsible for Nitrogen Catabolite Repression-sensitive transcriptional activation in the yeast Saccharomyces cerevisiae In nitrogen-replete medium, Gln3 is cytoplasmic and NCR-sensitive transcription is repressed.	Nitrogen	24-32	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	158-162
29113979-1	2018	Gln3 is responsible for Nitrogen Catabolite Repression-sensitive transcriptional activation in the yeast Saccharomyces cerevisiae In nitrogen-replete medium, Gln3 is cytoplasmic and NCR-sensitive transcription is repressed.	Nitrogen	133-141	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
29113979-1	2018	Gln3 is responsible for Nitrogen Catabolite Repression-sensitive transcriptional activation in the yeast Saccharomyces cerevisiae In nitrogen-replete medium, Gln3 is cytoplasmic and NCR-sensitive transcription is repressed.	Nitrogen	133-141	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	158-162
29113979-2	2018	In nitrogen-limiting medium, in cells treated with TorC1 inhibitor, rapamycin, or the glutamine synthetase inhibitor, methionine sulfoximine (Msx), Gln3 becomes highly nuclear and NCR-sensitive transcription derepressed.	Nitrogen	3-11	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	148-152
29113979-11	2018	These observations suggest that Gln3 responses to specific nitrogen environments likely occur in multiple steps that can be genetically separated.	Nitrogen	59-67	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	32-36
29747823-5	2018	We recount recent studies demonstrating strong, specific binding of alphaSyn to GM1 that serves to inhibit fibril formation and the key role of N-acetylation of alphaSyn in enhancing GM1 binding and specificity.	Nitrogen	144-145	synuclein, alpha	Mus musculus	161-169
30416219-3	2018	The EMEP MSC-W model with 50-km resolution was used for estimating the contribution of nitrogen emission sources from Poland to nitrogen deposition into the Baltic Sea basin and its sub-basins, in the period 1995-2014.	Nitrogen	87-95	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	164-167
31618189-2	2017	N-acetylcycteine (NAC) may reduce the risk of concomitant acute kidney injury (AKI) due to its antioxidant properties.	Nitrogen	0-16	synuclein alpha	Homo sapiens	18-21
29136381-7	2017	In addition, several IR bands of both FCH2CN-BCl3 and ClCH2CN-BCl3 were observed in nitrogen matrices, but the assigned bands are consistent with M06-2X predictions for the short-bond, minimum-energy structures.	Nitrogen	84-92	BCL3 transcription coactivator	Homo sapiens	38-49
29136381-7	2017	In addition, several IR bands of both FCH2CN-BCl3 and ClCH2CN-BCl3 were observed in nitrogen matrices, but the assigned bands are consistent with M06-2X predictions for the short-bond, minimum-energy structures.	Nitrogen	84-92	BCL3 transcription coactivator	Homo sapiens	45-49
28956227-3	2017	NTPDase3/CD39L3is dominantly expressed in pancreatic islet cells, where it may regulate insulin secretion, and has seven N-linked glycosylation sites with four close to five highly conserved domains called "apyrase conserved regions" (ACRs).	Nitrogen	0-1	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	9-15
29109265-0	2017	Diminished Ost3-dependent N-glycosylation of the BiP nucleotide exchange factor Sil1 is an adaptive response to reductive ER stress.	Nitrogen	26-27	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	11-15
29109265-5	2017	N-glycosylation of Sil1 is predominantly Ost3-dependent and requires a functional Ost3 CxxC thioredoxin motif.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	41-45
29109265-5	2017	N-glycosylation of Sil1 is predominantly Ost3-dependent and requires a functional Ost3 CxxC thioredoxin motif.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	82-86
29109265-6	2017	N-glycosylation of Lhs1 is largely Ost3-independent and independent of the CxxC motif.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	35-39
29109265-9	2017	We propose that reductive stress in the ER inhibits the Ost3-dependent N-glycosylation of Sil1, which regulates specific BiP functions appropriate to the needs of the ER under reductive stress.	Nitrogen	71-72	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	56-60
28640940-6	2017	The introduction of a suitable directing group at the nitrogen atom allows the preparation of C-2 alkenylated derivatives by transition metal catalyzed reactions.	Nitrogen	54-62	complement C2	Homo sapiens	94-97
29025995-3	2017	In our experiments, human breast cancer cells primarily assimilated ammonia through reductive amination catalyzed by glutamate dehydrogenase (GDH); secondary reactions enabled other amino acids, such as proline and aspartate, to directly acquire this nitrogen.	Nitrogen	251-259	glutamate dehydrogenase 1	Homo sapiens	142-145
29152581-5	2017	Overexpression of GTR1 impaired nitrogen starvation-induced filamentous growth, MEP2 expression, and growth in bovine serum albumin as the sole nitrogen source.	Nitrogen	32-40	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	18-22
29152581-5	2017	Overexpression of GTR1 impaired nitrogen starvation-induced filamentous growth, MEP2 expression, and growth in bovine serum albumin as the sole nitrogen source.	Nitrogen	144-152	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	18-22
29152581-13	2017	This study shows that GTR1 encodes a protein required for activation of TORC1 activity in response to amino acids and regulation of nitrogen starvation responses.	Nitrogen	132-140	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	22-26
29180998-4	2017	The N-glycosylation pattern is responsible for the secretion, uptake, and subcellular sorting of cystatin F in HeLa and Hek293 cells, whereas the legumain binding site had no effect on these processes.	Nitrogen	4-5	cystatin F	Homo sapiens	97-107
29121057-2	2017	We previously reported that the secretion of the bacterial enzyme Chondroitinase ABC by mammalian cells requires the strategic removal of at least three N-glycosylation sites.	Nitrogen	153-154	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	66-80
28880013-5	2017	Pretreatment with the N-linked glycosylation inhibitor tunicamycin, osimertinib clearly decreased the production of new PD-L1 protein probably due to a reduction in mRNA.	Nitrogen	22-23	CD274 molecule	Homo sapiens	120-125
29058647-1	2017	Yeast cells can use gamma-aminobutyric acid (GABA), a non-protein amino acid, as a nitrogen source that is mainly imported by the permease Uga4 and catabolized by the enzymes GABA transaminase and succinate-semialdehyde dehydrogenase, encoded by the UGA1 and UGA2 genes, respectively.	Nitrogen	83-91	Uga4p	Saccharomyces cerevisiae S288C	139-143
28784321-2	2017	In this study, the roles of YHM2, ODC1 and ODC2 in the assimilation of nitrogen and in the biosynthesis of lysine have been investigated.	Nitrogen	71-79	mitochondrial 2-oxodicarboxylate carrier	Saccharomyces cerevisiae S288C	43-47
27754725-5	2017	It was proposed that bioactivation of Compound 1 occurs via the formation of a di-iminoquinone reactive intermediate through the involvement of the C-2 and C-5 nitrogens of the pyrimidine core.	Nitrogen	160-169	complement C5	Homo sapiens	156-159
27754725-9	2017	Compounds 1 and 2, which bear secondary nitrogens at the C-5 of the pyrimidine core, were observed to form significant amounts of GSH/NAC-conjugates in vitro, whereas compounds with tertiary nitrogens at C-5 (Compound 3 and 4) formed no such conjugates.	Nitrogen	40-49	complement C5	Homo sapiens	57-60
29045410-7	2017	As previously reported for men, time to peak diversity in env-gp120 in women was positively associated with time to CD4+ cell count below 200 (P = 0.017), and the number of predicted N-linked glycosylation sites generally increased over time, followed by a plateau or decline, with the majority of changes localized to the V1-V2 region.	Nitrogen	183-184	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	62-67
29038508-6	2017	OTG bound specifically to Frizzled8 (Fz8) receptor and caused retention of Fz8 in the endoplasmic reticulum possibly by preventing N-linked glycosylation of Fz8.	Nitrogen	131-132	frizzled class receptor 8a	Danio rerio	26-35
29038508-6	2017	OTG bound specifically to Frizzled8 (Fz8) receptor and caused retention of Fz8 in the endoplasmic reticulum possibly by preventing N-linked glycosylation of Fz8.	Nitrogen	131-132	frizzled class receptor 8a	Danio rerio	37-40
27734716-1	2017	Synaptosomal-associated protein 25 kDa (SNAP-25) is one of the key proteins involved in the formation of neural soluble N-ethylmaleimide-sensitive factor attachment protein receptor complexes, which are responsible for the calcium-dependent exocytosis of neurotransmitters - a major step in neurotransmission and the key to normal functioning of brain.	Nitrogen	41-42	synaptosome associated protein 25	Homo sapiens	0-38
28627758-5	2017	The authors analysis indicated that the level of N-glycosylated peptides derived from galectin-3 binding proteins (LGALS3BP) were frequently elevated in plasma from PDAC patients, concurrent with the altered N-glycosylation of LGALS3BP observed in the tumor tissue.	Nitrogen	49-50	galectin 3 binding protein	Homo sapiens	115-123
28627758-5	2017	The authors analysis indicated that the level of N-glycosylated peptides derived from galectin-3 binding proteins (LGALS3BP) were frequently elevated in plasma from PDAC patients, concurrent with the altered N-glycosylation of LGALS3BP observed in the tumor tissue.	Nitrogen	49-50	galectin 3 binding protein	Homo sapiens	227-235
28627758-5	2017	The authors analysis indicated that the level of N-glycosylated peptides derived from galectin-3 binding proteins (LGALS3BP) were frequently elevated in plasma from PDAC patients, concurrent with the altered N-glycosylation of LGALS3BP observed in the tumor tissue.	Nitrogen	208-209	galectin 3 binding protein	Homo sapiens	115-123
28627758-7	2017	As one of the major binding ligands of galectin network, discovery of site specific N-glycosylation changes of LGALS3BP in association of PDAC may provide useful clues to facilitate cancer detection or phenotype stratification.	Nitrogen	84-85	galectin 3 binding protein	Homo sapiens	111-119
28712706-3	2017	SAR studies focused on the nitrogen atom of the piperazine moiety revealed that a phenyl group afforded potent inhibitory activity toward GSK-3beta.	Nitrogen	27-35	glycogen synthase kinase 3 beta	Mus musculus	138-147
29043425-11	2018	These results provide the first documentation that NAT1-catalyzed N-acetylation in PBMC is higher in T cell than in other immune cell subtypes and that individual variation in N-acetylation capacity is dependent upon NAT1 mRNA and NAT1 haplotype.	Nitrogen	51-52	N-acetyltransferase 1	Homo sapiens	217-221
29043425-11	2018	These results provide the first documentation that NAT1-catalyzed N-acetylation in PBMC is higher in T cell than in other immune cell subtypes and that individual variation in N-acetylation capacity is dependent upon NAT1 mRNA and NAT1 haplotype.	Nitrogen	66-67	N-acetyltransferase 1	Homo sapiens	51-55
29043425-11	2018	These results provide the first documentation that NAT1-catalyzed N-acetylation in PBMC is higher in T cell than in other immune cell subtypes and that individual variation in N-acetylation capacity is dependent upon NAT1 mRNA and NAT1 haplotype.	Nitrogen	66-67	N-acetyltransferase 1	Homo sapiens	217-221
29043425-11	2018	These results provide the first documentation that NAT1-catalyzed N-acetylation in PBMC is higher in T cell than in other immune cell subtypes and that individual variation in N-acetylation capacity is dependent upon NAT1 mRNA and NAT1 haplotype.	Nitrogen	66-67	N-acetyltransferase 1	Homo sapiens	217-221
28712706-4	2017	Docking studies indicated that the phenyl group on the piperazine nitrogen atom and the methyl group on the piperazine make cation-pi and CH-pi interactions with GSK-3beta respectively.	Nitrogen	66-74	glycogen synthase kinase 3 beta	Mus musculus	162-171
9726238-5	1998	Hypoxia (0.5% O2, 5% CO2, and 94.5% N2) stimulated GLUT1 mRNA expression in BRECs in a time-dependent manner with an 8.9 +/- 1.5-fold (P &lt; 0.01) increase observed after 12 h. GLUT1 mRNA expression returned to baseline (1.4 +/- 0.3-fold of control) within 12 h after reinstitution of normoxia.	Nitrogen	36-38	solute carrier family 2 member 1	Bos taurus	178-183
11670520-9	1998	Electron spin-echo envelope modulation (ESEEM) spectroscopy data, particularly the nuclear quadrupole interaction (NQI) parameters e(2)qQ and eta of the remote nitrogen (N1H), were analyzed and interpreted according to the model devised by Jiang et al.	Nitrogen	160-168	endothelin receptor type A	Homo sapiens	142-145
28715013-4	2017	Accordingly, the MagG@COF-5 biocomposite showed excellent performance in N-linked glycopeptide analysis with a low detection limit (0.5 fmol muL-1), an excellent size-exclusion effect (HRP digests/BSA, 1 : 600), good recyclability and reusability.	Nitrogen	73-74	mitochondrial E3 ubiquitin protein ligase 1	Homo sapiens	141-146
11670520-15	1998	The results are the following: (i) C2 substitution of the imidazole ring, next to the remote nitrogen (1, 2) decreases the asymmetry parameter eta to ca.	Nitrogen	93-101	endothelin receptor type A	Homo sapiens	143-146
28433878-7	2017	In the ambient sediments, smaller particle size and higher levels of organic matter and nutrients (nitrogen and phosphorus) were associated with increased persistence of the GB3 marker and culturable Escherichia coli (cEC) and enterococci (cENT).	Nitrogen	99-107	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	174-177
9653080-3	1998	We report here that the VAP-1 cDNA encodes a type II transmembrane protein of 84.6 kD with a single transmembrane domain located at the NH2-terminal end of the molecule and six potential N-glycosylation sites in the extracellular domain.	Nitrogen	32-33	amine oxidase copper containing 3	Homo sapiens	24-29
28794626-5	2017	At nitrogen:phosphate (N:P) ratios of 10 or above, the FA-PEG-SS-PEI-SPIONs bound to PD-L1 siRNA to form a polyplex with a diameter of approximately 120 nm.	Nitrogen	3-11	CD274 molecule	Homo sapiens	85-90
9637683-7	1998	Finally, overexpression of wild-type hIre1p constitutively activated a reporter gene under transcriptional control of the rat BiP promoter, whereas expression of a catalytically inactive hIre1p acted in a trans-dominant-negative manner to prevent transcriptional activation of the BiP promoter in response to ER stress induced by inhibition of N-linked glycosylation.	Nitrogen	344-345	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	37-43
28032462-0	2017	Synthesis and biological evaluation of N-acylated tyramine sulfamates containing C-F bonds as steroid sulfatase inhibitors.	Nitrogen	39-40	steroid sulfatase	Homo sapiens	94-111
9614085-5	1998	K+ starvation and nitrogen starvation hyperpolarize both TRK1 TRK2 and trk1Delta trk2Delta cells, thus suggesting that other proteins, in addition to Trk1p and Trk2p, participate in the control of the membrane potential.	Nitrogen	18-26	Trk1p	Saccharomyces cerevisiae S288C	150-155
31457631-4	2017	Consequently, N-doped porous CTF/CSF microfibrillar biochars displayed a distinguished capture capacity toward SB compared to that of their fibrillar precursors.	Nitrogen	14-15	colony stimulating factor 2	Homo sapiens	33-36
28388573-6	2017	What is more, when detect the function of alphaMSH in ROS-induced apoptosis, similar inhibitory trend was found with the oxidative stress inhibitor N-acetyl-L-cysteine (NAC) in ROS-induced adipocyte apoptosis and this trend is alphaMSH receptor melanocortin 5 receptor (MC5R) depended, while an opposite trend was found between alphaMSH and Foxo1, which is a known positive regulator of adipocyte apoptosis.	Nitrogen	148-149	forkhead box O1	Mus musculus	341-346
12580037-3	1998	Based on the cell-frozen principle, the Rb cell line was collected and established, then frozen in liquid nitrogen and resuscitated.	Nitrogen	106-114	RB transcriptional corepressor 1	Homo sapiens	40-42
26608959-3	2017	Considering that N-glycosylation is one of the most ubiquitous post-translational modifications for many eukaryotic proteins, the HMT-1 could be postulated as one of the housekeeping genes, but its transcriptional regulation remains to be investigated.	Nitrogen	17-18	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	130-135
12580037-7	1998	CONCLUSION: The preserved human Rb cells in liquid nitrogen grew normally after resuscitation with the maintenance of previous bioactivities and characteristics.	Nitrogen	51-59	RB transcriptional corepressor 1	Homo sapiens	32-34
28611503-5	2017	The phosphate-starved Scenedesmus cells, with an initial cell density of, 1 x 106 cells mL-1 shows 87% phosphate and 100 % nitrogen removal in 24 h. The normal Scenedesmus cells need approximately 48 h to trim down the nutrients from wastewater up to this extent.	Nitrogen	123-131	L1 cell adhesion molecule	Mus musculus	88-92
9596633-8	1998	Although these results suggest a major role for GLU1 in photorespiration, the sucrose induction of GLU1 mRNA in leaves also suggests a role in primary nitrogen assimilation.	Nitrogen	151-159	glutamate synthase 1	Arabidopsis thaliana	99-103
9596633-10	1998	Both the mutant analysis and gene regulation studies suggest that GLU1 plays a major role in photorespiration and also plays a role in primary nitrogen assimilation in leaves, whereas the GLU2 gene may play a major role in primary nitrogen assimilation in roots.	Nitrogen	143-151	glutamate synthase 1	Arabidopsis thaliana	66-70
9587408-0	1998	The role of N-glycosylation of human thromboxane A2 receptor in ligand binding.	Nitrogen	12-13	thromboxane A2 receptor	Homo sapiens	37-60
28242278-1	2017	Nitrogen and phosphorus loads are considered a major reason for the eutrophication of the Baltic Sea.	Nitrogen	0-8	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	97-100
9560430-2	1998	In the absence of glucose and nitrogen, IME1 expression is greater in a/alpha cells than in either a or alpha cells and therefore only a/alpha, but not a/a or alpha/alpha, cells are committed to sporulation.	Nitrogen	30-38	transcription factor IME1	Saccharomyces cerevisiae S288C	40-44
9544990-0	1998	N-glycosylation of the prolactin receptor is not required for activation of gene transcription but is crucial for its cell surface targeting.	Nitrogen	0-1	prolactin receptor	Homo sapiens	23-41
28204735-7	2017	On d 14, the apparent total tract digestibility (ATTD) of DM, nitrogen (N), and gross energy (GE) was increased (P &lt; 0.05) by LPL supplementation.	Nitrogen	62-70	lipoprotein lipase	Homo sapiens	129-132
30108834-4	2017	A SAR study shows that the sigma1R requires the presence of relatively highly lipophilic substituents at opposite sides of the central scaffold, while selectivity versus the sigma2R can be improved by shortening the distance of the basic nitrogen to it.	Nitrogen	238-246	sigma non-opioid intracellular receptor 1	Mus musculus	27-34
9545574-7	1998	PLP-F cDNA encodes for a predicted 267 amino acid protein containing a 30 amino acid signal peptide and three putative N-linked glycosylation sites.	Nitrogen	8-9	prolactin family 7, subfamily a, member 2	Mus musculus	0-5
31844330-13	2017	We derived a rotational temperature of T rot=13+-1 K, and a total column density of N HCN=1.6+-0.1x1016 cm-2 for V4334 Sgr.	Nitrogen	84-85	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	86-89
9450955-1	1998	C-mannosylation of Trp-7 in human ribonuclease 2 (RNase 2) is a novel kind of protein glycosylation that differs fundamentally from N- and O-glycosylation in the protein-sugar linkage.	Nitrogen	51-52	transient receptor potential cation channel subfamily C member 7	Homo sapiens	19-24
28199092-4	2017	In this paper we describe the application of an MAM based method for site specific quantification of N-linked glycan heterogeneity present on an IgG1 mAb molecule containing two distinct N-linked glycosylation sites: one present on the heavy chain (HC) variable region (Fab) and the other present on the conserved HC constant region (Fc).	Nitrogen	101-102	FA complementation group B	Homo sapiens	270-273
29398870-9	2018	Further multivariate analysis revealed that only the T/N ratio was significantly correlated with GPC3 expression in patients with HCC (P &lt; 0.05).	Nitrogen	55-56	glypican 3	Homo sapiens	97-101
9450955-1	1998	C-mannosylation of Trp-7 in human ribonuclease 2 (RNase 2) is a novel kind of protein glycosylation that differs fundamentally from N- and O-glycosylation in the protein-sugar linkage.	Nitrogen	51-52	ribonuclease A family member 2	Homo sapiens	34-48
29278502-5	2018	Due to an effective pi-pi interaction, a thermally activated charge transfer from [SnII(Pc 3-)] - to (cis-indigo-N,N)2- is observed, with an estimated Gibbs energy (-DeltaG ) of 9.27 +- 0.18 kJ/mol.	Nitrogen	113-114	chromobox 8	Homo sapiens	88-92
28247897-0	2017	Solvothermal self-assembly of Cd2+ coordination polymers with supramolecular networks involving N-donor ligands and aromatic dicarboxylates: synthesis, crystal structure and photoluminescence studies.	Nitrogen	96-97	CD2 molecule	Homo sapiens	30-33
9551918-0	1998	Distinct patterns of folding and interactions with calnexin and calreticulin in human class I MHC proteins with altered N-glycosylation.	Nitrogen	120-121	calnexin	Homo sapiens	51-59
29302060-2	2018	Here we demonstrate that the repeat-associated non-AUG (RAN) translation of (GGGGCC) n -containing RNAs into poly-dipeptides can initiate in vivo without a 5"-cap.	Nitrogen	12-13	RAN, member RAS oncogene family	Homo sapiens	56-59
28133833-2	2017	Upon mild heating, the ambiphilic molecule (2-NMe2 -C6 H4 )2 BH activates the C-H bond of a methyl group in alpha position of a nitrogen atom to generate an unprecedented N-B heterocycle.	Nitrogen	128-136	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	46-50
9600390-3	1998	The nitrogen/air mixture led to a decrease in tissue oxygen, an increase in rCBF, a decrease in extracellular glucose, and an increase in lactate.	Nitrogen	4-12	CCAAT/enhancer binding protein zeta	Rattus norvegicus	76-80
28219627-5	2017	Our data demonstrated ATIII significantly attenuated the elevation of serum creatinine, blood urea nitrogen, and renal histological injury.	Nitrogen	99-107	serpin family C member 1	Homo sapiens	22-27
29607936-9	2018	Moreover, we found that STT3B-dependent posttranslational N-glycosylation at N98 residue occurred in G101S TTR but not in other TTR variants, possibly due to amino acid alterations that increase N-glycosylation preference or accelerate rigid structure formation susceptible to N-glycosylation.	Nitrogen	58-59	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	24-29
28643274-4	2018	A type 2 serum transferrin isoelectrofocusing and hypoglycosylation of apoCIII pointed to a combined N- and O-glycosylation defect.	Nitrogen	101-102	apolipoprotein C3	Homo sapiens	71-78
29289724-9	2018	CHS3 a major chitin synthase gene was also found to be upregulated, and the transcript abundance of key genes of central nitrogen metabolism, GLN1, GLT1, GDH1 and GDH2 in mutant  ecm33 were also altered.	Nitrogen	121-129	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	163-167
29289724-9	2018	CHS3 a major chitin synthase gene was also found to be upregulated, and the transcript abundance of key genes of central nitrogen metabolism, GLN1, GLT1, GDH1 and GDH2 in mutant  ecm33 were also altered.	Nitrogen	121-129	Ecm33p	Saccharomyces cerevisiae S288C	179-184
30416219-0	2018	Contribution of Poland to Atmospheric Nitrogen Deposition to the Baltic Sea.	Nitrogen	38-46	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	72-75
30416219-1	2018	Poland is the second most important emission source after Germany in contributing atmospheric nitrogen deposition to the Baltic Sea basin.	Nitrogen	94-102	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	128-131
27838555-0	2017	Tri-iodide reduction activity of ultra-small size PtFe nanoparticles supported nitrogen-doped graphene as counter electrode for dye-sensitized solar cell.	Nitrogen	79-87	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	0-3
28150006-8	2017	ArCN+, on the other hand, has a dipole moment of greater than 3.5 D, an observable C-N stretching fundamental at 2189.6 cm-1 (4.567 microns), and a viable formation pathway through HCN, a highly-abundant interstellar molecule.	Nitrogen	3-4	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	181-184
9820842-1	1998	Based on sequence analysis, the protein encoded by the US5 open reading frame (ORF) of herpes simplex virus type 1 (HSV-1) was predicted to contain an N-glycosylation site and was given the designation of glycoprotein J (gJ).	Nitrogen	151-152	envelope glycoprotein J	Human alphaherpesvirus 1	55-58
28243336-6	2017	Further studies showed that the regulated beta3GnT8 could convert the heterogeneous N-glycosylated forms of CD147 and change the polylactosamine structures carried on CD147.	Nitrogen	84-85	basigin (Ok blood group)	Homo sapiens	108-113
28243336-6	2017	Further studies showed that the regulated beta3GnT8 could convert the heterogeneous N-glycosylated forms of CD147 and change the polylactosamine structures carried on CD147.	Nitrogen	84-85	basigin (Ok blood group)	Homo sapiens	167-172
29122887-8	2017	We applied PRT to the Pro/N-end rule pathway, whose substrates include the short-lived Mdh2 malate dehydrogenase.	Nitrogen	26-27	malate dehydrogenase MDH2	Saccharomyces cerevisiae S288C	87-91
21374492-4	1998	There are 22-31 potential N-linked glycosylation sites on gp120 depending on the HIV-1 isolate and thus, approximately half of its molecular weight is composed of carbohydrate.	Nitrogen	26-27	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	58-63
29189009-3	2017	Silver salt was found to efficiently promote indole annulation to give multifunctional benzo[g]indoles with the installation of two sulfonyl groups into the indole ring via N-S and N-F bond cleavage of NFSI, whereas NBS and NCS-mediated benzannulations occurred with the formation of dihalogenated 1-naphthols.	Nitrogen	173-174	nibrin	Homo sapiens	216-219
27966990-0	2017	Site-Specific N-Glycosylation of Endothelial Cell Receptor Tyrosine Kinase VEGFR-2.	Nitrogen	14-15	ret proto-oncogene	Homo sapiens	50-74
27966990-3	2017	N-glycosylation plays a central role in RTK ligand binding, trafficking, and stability.	Nitrogen	0-1	ret proto-oncogene	Homo sapiens	40-43
9409822-5	1997	Mutations in LST4 and LST7 reduce the activity of the nitrogen-regulated permeases Gap1p and Put4p, whereas mutations in LST8 impair the activities of a broader set of amino acid permeases.	Nitrogen	54-62	proline permease PUT4	Saccharomyces cerevisiae S288C	93-98
28975712-6	2017	The N-nonyl analogue 35 b displayed a Ki value of &lt;&lt;14 nm for GBA1 inhibition and a Ki of 43 nm for GBA2.	Nitrogen	4-5	glucosylceramidase beta	Homo sapiens	68-72
9409822-5	1997	Mutations in LST4 and LST7 reduce the activity of the nitrogen-regulated permeases Gap1p and Put4p, whereas mutations in LST8 impair the activities of a broader set of amino acid permeases.	Nitrogen	54-62	TOR complex subunit LST8	Saccharomyces cerevisiae S288C	121-125
28060513-5	2017	The two corresponding transitions occur at water/EO/n-hexanol molar ratios of 2/1/2 (clear to lamella), and 3/1/2 (lamella to microemulsion), while phase separation occurs at a molar ratio of 4/1/2, highlighting the important role of stoichiometry.	Nitrogen	16-17	WD repeat and HMG-box DNA binding protein 1	Homo sapiens	104-113
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Gat1p	Saccharomyces cerevisiae S288C	116-121
27884519-4	2017	Modified vectors were constructed by introducing N- or O-glycosylation site on the region of hIL-11 that does not belong to the core alpha-helical motif based on the predicted secondary structure.	Nitrogen	49-50	interleukin 11	Homo sapiens	93-99
29054975-1	2017	The Neurospora crassa NIT-2 transcription factor belongs to the GATA transcription factor family and plays a fundamental role in the regulation of nitrogen metabolism by N. crassa Because NIT-2 acts by accessing DNA inside the nucleus, understanding the nuclear import process of NIT-2 is necessary to characterize its function.	Nitrogen	147-155	nitrilase family member 2	Homo sapiens	22-27
29054975-1	2017	The Neurospora crassa NIT-2 transcription factor belongs to the GATA transcription factor family and plays a fundamental role in the regulation of nitrogen metabolism by N. crassa Because NIT-2 acts by accessing DNA inside the nucleus, understanding the nuclear import process of NIT-2 is necessary to characterize its function.	Nitrogen	147-155	nitrilase family member 2	Homo sapiens	188-193
29054975-1	2017	The Neurospora crassa NIT-2 transcription factor belongs to the GATA transcription factor family and plays a fundamental role in the regulation of nitrogen metabolism by N. crassa Because NIT-2 acts by accessing DNA inside the nucleus, understanding the nuclear import process of NIT-2 is necessary to characterize its function.	Nitrogen	147-155	nitrilase family member 2	Homo sapiens	188-193
28976047-0	2017	Target of rapamycin complex 1 and Tap42-associated phosphatases are required for sensing changes in nitrogen conditions in the yeast Saccharomyces cerevisiae.	Nitrogen	100-108	Tap42p	Saccharomyces cerevisiae S288C	34-39
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Gat1p	Saccharomyces cerevisiae S288C	122-127
28976047-1	2017	In yeast target of rapamycin complex 1 (TORC1) and Tap42-associated phosphatases regulate expression of genes involved in nitrogen limitation response and the nitrogen discrimination pathway.	Nitrogen	122-130	Tap42p	Saccharomyces cerevisiae S288C	51-56
28976047-1	2017	In yeast target of rapamycin complex 1 (TORC1) and Tap42-associated phosphatases regulate expression of genes involved in nitrogen limitation response and the nitrogen discrimination pathway.	Nitrogen	159-167	Tap42p	Saccharomyces cerevisiae S288C	51-56
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Gzf3p	Saccharomyces cerevisiae S288C	161-166
26972592-5	2017	BcATG1 could functionally restore the survival defects of the yeast ATG1 mutant during nitrogen starvation.	Nitrogen	87-95	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	2-6
27891735-1	2017	Ornithine transcarbamylase deficiency (OTCD) is a urea cycle disorder of X-linked inheritance, affecting the detoxification of excess nitrogen and leading to hyperammonemia (hyper-NH3 ).	Nitrogen	134-142	ornithine transcarbamylase	Homo sapiens	0-26
27908775-2	2017	General amino acid permease Gap1p is response of aromatic amino acids transportation, and GATA transcription factors Gln3p and Gat1p regulate the transcription of permease gene and catabolic enzyme genes for nitrogen sources and aromatic amino acids utilization.	Nitrogen	208-216	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	117-122
28976047-3	2017	Utilizing temperature sensitive mutants of tor2 and tap42, we examined the role of TORC1 and Tap42 in nuclear entry of Gln3, a key transcription factor in yeast nitrogen metabolism, in response to changes in nitrogen conditions.	Nitrogen	208-216	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	119-123
28976047-4	2017	Our data show that TORC1 is essential for Gln3 nuclear entry upon nitrogen limitation and downshift in nitrogen quality.	Nitrogen	66-74	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
28976047-4	2017	Our data show that TORC1 is essential for Gln3 nuclear entry upon nitrogen limitation and downshift in nitrogen quality.	Nitrogen	103-111	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
28976047-5	2017	However, Tap42-associated phosphatases are required only under nitrogen limitation condition.	Nitrogen	63-71	Tap42p	Saccharomyces cerevisiae S288C	9-14
28976047-6	2017	In cells grown in poor nitrogen medium, the nitrogen permease reactivator kinase (Npr1) inhibits TORC1 activity and alters its association with Tap42, rendering Tap42-associated phosphatases unresponsive to nitrogen limitation.	Nitrogen	44-52	Tap42p	Saccharomyces cerevisiae S288C	144-149
28976047-6	2017	In cells grown in poor nitrogen medium, the nitrogen permease reactivator kinase (Npr1) inhibits TORC1 activity and alters its association with Tap42, rendering Tap42-associated phosphatases unresponsive to nitrogen limitation.	Nitrogen	44-52	Tap42p	Saccharomyces cerevisiae S288C	161-166
28976047-7	2017	These findings demonstrate a direct role for TORC1 and Tap42-associated phosphatases in sensing nitrogen conditions and unveil an Npr1-dependent mechanism that controls TORC1 and the phosphatases in response to changes in nitrogen quality.	Nitrogen	96-104	Tap42p	Saccharomyces cerevisiae S288C	55-60
28976047-7	2017	These findings demonstrate a direct role for TORC1 and Tap42-associated phosphatases in sensing nitrogen conditions and unveil an Npr1-dependent mechanism that controls TORC1 and the phosphatases in response to changes in nitrogen quality.	Nitrogen	222-230	Tap42p	Saccharomyces cerevisiae S288C	55-60
28956227-0	2017	Various N-glycoforms differentially upregulate E-NTPDase activity of the NTPDase3/CD39L3 ecto-enzymatic domain.	Nitrogen	8-9	ectonucleoside triphosphate diphosphohydrolase 8	Homo sapiens	47-56
28956227-0	2017	Various N-glycoforms differentially upregulate E-NTPDase activity of the NTPDase3/CD39L3 ecto-enzymatic domain.	Nitrogen	8-9	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	73-81
27641734-3	2017	The aim of this study was to elucidate the extracellular molecular basis of the CD97 EGF1-5 isoform in protein expression, auto-proteolysis and cell adhesion, including epidermal growth factor (EGF)-like domain, GPCR autoproteolysis-inducing (GAIN) domain, as well as GPS mutagenesis and N-glycosylation.	Nitrogen	246-247	adhesion G protein-coupled receptor E5	Homo sapiens	80-84
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Gzf3p	Saccharomyces cerevisiae S288C	167-172
27641734-3	2017	The aim of this study was to elucidate the extracellular molecular basis of the CD97 EGF1-5 isoform in protein expression, auto-proteolysis and cell adhesion, including epidermal growth factor (EGF)-like domain, GPCR autoproteolysis-inducing (GAIN) domain, as well as GPS mutagenesis and N-glycosylation.	Nitrogen	246-247	G elongation factor mitochondrial 1	Homo sapiens	85-91
27641734-7	2017	Potential N-glycosylation sites were identified using MS and were modulated with PNGase F digestion and glyco-site mutations.	Nitrogen	10-11	N-glycanase 1	Homo sapiens	81-87
28956227-0	2017	Various N-glycoforms differentially upregulate E-NTPDase activity of the NTPDase3/CD39L3 ecto-enzymatic domain.	Nitrogen	8-9	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	82-88
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Gzf3p	Saccharomyces cerevisiae S288C	173-178
27641734-10	2017	N-glycosylation affected the auto-proteolysis of CD97 EGF1-5 isoform in a similar way as the other previously reported CD97 isoforms.	Nitrogen	0-1	adhesion G protein-coupled receptor E5	Homo sapiens	49-53
9522467-0	1997	Changes in soluble sugar, starch, and alcohol dehydrogenase in Arabidopsis thaliana exposed to N2 diluted atmospheres.	Nitrogen	95-97	alcohol dehydrogenase 1	Arabidopsis thaliana	38-59
27641734-10	2017	N-glycosylation affected the auto-proteolysis of CD97 EGF1-5 isoform in a similar way as the other previously reported CD97 isoforms.	Nitrogen	0-1	G elongation factor mitochondrial 1	Homo sapiens	54-60
27641734-10	2017	N-glycosylation affected the auto-proteolysis of CD97 EGF1-5 isoform in a similar way as the other previously reported CD97 isoforms.	Nitrogen	0-1	adhesion G protein-coupled receptor E5	Homo sapiens	119-123
27641734-16	2017	A comparison of the HeLa binding affinities of PNGase F-digested, GPS-mutated and N-glycosylation-mutated CD97 samples revealed diverse findings, suggesting that the functions of CD97 ECD were complex, and various technologies for function validation should be utilized to avoid single-approach bias when investigating N-glycosylation and auto-proteolysis of CD97.	Nitrogen	48-49	adhesion G protein-coupled receptor E5	Homo sapiens	179-183
27641734-16	2017	A comparison of the HeLa binding affinities of PNGase F-digested, GPS-mutated and N-glycosylation-mutated CD97 samples revealed diverse findings, suggesting that the functions of CD97 ECD were complex, and various technologies for function validation should be utilized to avoid single-approach bias when investigating N-glycosylation and auto-proteolysis of CD97.	Nitrogen	48-49	adhesion G protein-coupled receptor E5	Homo sapiens	179-183
27641734-16	2017	A comparison of the HeLa binding affinities of PNGase F-digested, GPS-mutated and N-glycosylation-mutated CD97 samples revealed diverse findings, suggesting that the functions of CD97 ECD were complex, and various technologies for function validation should be utilized to avoid single-approach bias when investigating N-glycosylation and auto-proteolysis of CD97.	Nitrogen	82-83	N-glycanase 1	Homo sapiens	47-53
27641734-16	2017	A comparison of the HeLa binding affinities of PNGase F-digested, GPS-mutated and N-glycosylation-mutated CD97 samples revealed diverse findings, suggesting that the functions of CD97 ECD were complex, and various technologies for function validation should be utilized to avoid single-approach bias when investigating N-glycosylation and auto-proteolysis of CD97.	Nitrogen	82-83	adhesion G protein-coupled receptor E5	Homo sapiens	106-110
27641734-16	2017	A comparison of the HeLa binding affinities of PNGase F-digested, GPS-mutated and N-glycosylation-mutated CD97 samples revealed diverse findings, suggesting that the functions of CD97 ECD were complex, and various technologies for function validation should be utilized to avoid single-approach bias when investigating N-glycosylation and auto-proteolysis of CD97.	Nitrogen	82-83	adhesion G protein-coupled receptor E5	Homo sapiens	179-183
27641734-16	2017	A comparison of the HeLa binding affinities of PNGase F-digested, GPS-mutated and N-glycosylation-mutated CD97 samples revealed diverse findings, suggesting that the functions of CD97 ECD were complex, and various technologies for function validation should be utilized to avoid single-approach bias when investigating N-glycosylation and auto-proteolysis of CD97.	Nitrogen	82-83	adhesion G protein-coupled receptor E5	Homo sapiens	179-183
27670784-0	2017	Quantitative study of yeast Alg1 beta-1, 4 mannosyltransferase activity, a key enzyme involved in protein N-glycosylation.	Nitrogen	106-107	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	28-32
28887235-0	2017	Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration.	Nitrogen	10-11	tachykinin 1	Mus musculus	31-42
29152581-2	2017	Gtr1 encodes a highly conserved GTPase that in Saccharomyces cerevisiae regulates nitrogen sensing and TORC1 activation.	Nitrogen	82-90	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	0-4
28914590-4	2017	Similarly, Rab proteins (Rab3d, Rab11a, Rab11b, Rab27a, and Rab27b) and soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) proteins VAMP4, VAMP8, syntaxin-2, syntaxin-3, syntaxin-4, and syntaxin-6 were expressed at various levels in individual glands.	Nitrogen	80-81	vesicle associated membrane protein 4	Canis lupus familiaris	167-172
9312136-5	1997	We have been using N-glycosylation substitution mutants to map the extracellular topology of ROMK1 biochemically and have described several loci in H5 that were glycosylated.	Nitrogen	19-20	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	93-98
29163391-9	2017	Furthermore, the urea nitrogen and serum creatinine levels significantly increased in the contaminated tea-drinking mice.	Nitrogen	22-30	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	Mus musculus	103-106
27773703-0	2017	N-Glycoform-dependent interactions of megalin with its ligands.	Nitrogen	0-1	low density lipoprotein receptor-related protein 2	Mus musculus	38-45
27773703-3	2017	Megalin has 30 potential N-glycosylation sites in its extracellular domain.	Nitrogen	25-26	low density lipoprotein receptor-related protein 2	Mus musculus	0-7
27773703-16	2017	CONCLUSIONS: N-Glycosylation of megalin can modulate its ligand-binding activity.	Nitrogen	2-3	low density lipoprotein receptor-related protein 2	Mus musculus	32-39
9278412-2	1997	Despite a low overall amino acid sequence identity of approximately 30%, it shares several features with Dal80p/Uga43p and Gzf3p/Nil2p, both repressors in nitrogen metabolism in Saccharomyces cerevisiae.	Nitrogen	155-163	Gzf3p	Saccharomyces cerevisiae S288C	123-128
27098170-6	2017	Furthermore, the PEF-treated SAP1&lt;MW&lt;3kDa under optimal conditions lacked the characteristic absorbance of N-H, C = C and the amide band and the zeta potential was reduced to -18.0 mV.	Nitrogen	113-114	protein tyrosine phosphatase receptor type H	Homo sapiens	29-33
28803208-6	2017	In addition, UGT1A4 and UGT2B10 were primarily responsible for N-glucuronidation of many tertiary amines, including asenapine, loxapine, clozapine, chlorpromazine, dothiepin, doxepin, mirtazapine, mianserin, chlorcyclizine, cyclizine, promethazine, cyclobenzaprine, imatinib, retrorsine, strychnine and brucine.	Nitrogen	63-64	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	13-19
28803208-6	2017	In addition, UGT1A4 and UGT2B10 were primarily responsible for N-glucuronidation of many tertiary amines, including asenapine, loxapine, clozapine, chlorpromazine, dothiepin, doxepin, mirtazapine, mianserin, chlorcyclizine, cyclizine, promethazine, cyclobenzaprine, imatinib, retrorsine, strychnine and brucine.	Nitrogen	63-64	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	24-31
28803208-8	2017	Also, UGT1A4- and UGT2B10-mediated N-glucuronidation might play significant roles in metabolism and detoxification of tertiary amines in humans.	Nitrogen	35-36	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	6-12
28803208-8	2017	Also, UGT1A4- and UGT2B10-mediated N-glucuronidation might play significant roles in metabolism and detoxification of tertiary amines in humans.	Nitrogen	35-36	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	18-25
27834568-6	2017	Removal of the Fab N-glycosylation site by single amino acid substitution, or removal of N-linked glycans by enzymatic digestion, drastically reduced the antibody"s ability to inhibit latency-associated peptide (LAP) and alphavbeta8 association, and TGF-beta activation in an alphavbeta8-mediated TGF-beta signaling reporter assay.	Nitrogen	19-20	FA complementation group B	Homo sapiens	15-18
9278412-2	1997	Despite a low overall amino acid sequence identity of approximately 30%, it shares several features with Dal80p/Uga43p and Gzf3p/Nil2p, both repressors in nitrogen metabolism in Saccharomyces cerevisiae.	Nitrogen	155-163	Gzf3p	Saccharomyces cerevisiae S288C	129-134
9290152-3	1997	It is hypothesized that TfR isolated from diabetic placentae has altered N-glycosylation since proper glycosylation of N-linked oligosaccharides is important for normal TfR binding kinetics to diferric transferrin.	Nitrogen	73-74	transferrin receptor	Homo sapiens	24-27
29449910-0	2017	Design, Synthesis and Preliminary Antimicrobial Evaluation of N-Alkyl Chain Tethered C-5 Functionalized Bis-Isatins.	Nitrogen	62-63	complement C5	Homo sapiens	85-88
28664184-3	2017	Our previous work showed that the SCAP/SREBP-1 pathway is significantly upregulated in human glioblastoma (GBM), the most deadly brain cancer, and that glucose-mediated N-glycosylation of SCAP is a prerequisite step for SCAP/SREBP trafficking.	Nitrogen	169-170	sterol regulatory element binding transcription factor 1	Homo sapiens	39-46
27956623-3	2016	By comparative gene expression profiling of p53-mutated and p53-depleted cancer cells, we identified ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a mutant p53 target gene, which functions as a uridine 5"-diphosphatase (UDPase) in the endoplasmic reticulum (ER) to promote the folding of N-glycosylated membrane proteins.	Nitrogen	152-153	transformation related protein 53, pseudogene	Mus musculus	44-47
27956623-3	2016	By comparative gene expression profiling of p53-mutated and p53-depleted cancer cells, we identified ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a mutant p53 target gene, which functions as a uridine 5"-diphosphatase (UDPase) in the endoplasmic reticulum (ER) to promote the folding of N-glycosylated membrane proteins.	Nitrogen	152-153	transformation related protein 53, pseudogene	Mus musculus	60-63
28898470-2	2017	It fills the gap between the congeneric compounds [ClP(mu-NR)]2 and [ClP(mu-PR)]2 (R=sterically demanding substituent), and thus contributes to the systematic development of nitrogen-phosphorus chemistry in general.	Nitrogen	174-182	calmodulin like 3	Homo sapiens	69-72
29051766-7	2017	Thus, ZmNLP6 and ZmNLP8 regulate nitrate signaling in transgenic Arabidopsis plants and may be potential candidates for improving nitrogen use efficiency of maize.	Nitrogen	130-138	Protein NLP3	Zea mays	17-23
27956623-3	2016	By comparative gene expression profiling of p53-mutated and p53-depleted cancer cells, we identified ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a mutant p53 target gene, which functions as a uridine 5"-diphosphatase (UDPase) in the endoplasmic reticulum (ER) to promote the folding of N-glycosylated membrane proteins.	Nitrogen	152-153	transformation related protein 53, pseudogene	Mus musculus	60-63
9280298-3	1997	This structural information is based on nearly complete sequence-specific assignments for the backbone amide nitrogens, amide protons and alpha-protols of the polypeptide segment of residues 121-231 in mPrP(23-231).	Nitrogen	109-118	prion protein	Mus musculus	202-206
28193043-0	2016	Removal of N-Linked Glycosylations at Acidic pH by PNGase A Facilitates Hydrogen/Deuterium Exchange Mass Spectrometry Analysis of N-Linked Glycoproteins.	Nitrogen	11-12	N-glycanase 1	Homo sapiens	51-57
27732771-11	2016	Results Reduced amounts of N-linked and O-linked sialylation resulted in enhanced pd-VWF clearance modulated via ASGPR.	Nitrogen	27-28	Von Willebrand factor	Mus musculus	85-88
29081462-0	2017	Association between Nitrogen Stable Isotope Ratios in Human Hair and Serum Levels of Leptin.	Nitrogen	20-28	leptin	Homo sapiens	85-91
29081462-4	2017	We investigated whether the carbon and nitrogen stable isotope ratios in hair are associated with serum leptin levels.	Nitrogen	39-47	leptin	Homo sapiens	104-110
29081462-11	2017	The nitrogen stable isotopic ratio in hair is positively associated with serum leptin levels.	Nitrogen	4-12	leptin	Homo sapiens	79-85
28315854-6	2017	We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3beta/beta-catenin signaling pathway, which further adjusted MMP2/9 expression and activities.	Nitrogen	29-30	catenin beta 1	Homo sapiens	107-119
9294006-2	1997	Mouse CD151 mRNA comprises approximately 1.8 kb, has 253 amino acid residues with 93% identity to human CD151 and contains four putative transmembrane domains, a number of cysteine residues and one potential N-glycosylation site located at a site corresponding to that in human CD151.	Nitrogen	14-15	CD151 antigen	Mus musculus	6-11
28831469-2	2017	Selective catalytic combustion of HCN (HCN-SCC) over metal modified zeolite catalysts has attracted great attention due to related high efficiency and excellent N2 selectivity.	Nitrogen	161-163	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	34-37
28831469-2	2017	Selective catalytic combustion of HCN (HCN-SCC) over metal modified zeolite catalysts has attracted great attention due to related high efficiency and excellent N2 selectivity.	Nitrogen	161-163	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	39-46
28679684-4	2017	Adding a preferred nitrogen source to proline-grown cells triggers Gap1 endocytosis and vacuolar degradation in an Rsp5-Bul1/2-dependent manner.	Nitrogen	19-27	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	115-119
27882940-8	2016	Doxycycline-induced deletion of MDM2 in tubular cell-specific MDM2-knockout mice Pax8rtTa-cre; MDM2f/f caused acute kidney injury with increased plasma creatinine and blood urea nitrogen and sharp decline of glomerular filtration rate.	Nitrogen	178-186	transformed mouse 3T3 cell double minute 2	Mus musculus	32-36
27882940-8	2016	Doxycycline-induced deletion of MDM2 in tubular cell-specific MDM2-knockout mice Pax8rtTa-cre; MDM2f/f caused acute kidney injury with increased plasma creatinine and blood urea nitrogen and sharp decline of glomerular filtration rate.	Nitrogen	178-186	transformed mouse 3T3 cell double minute 2	Mus musculus	62-66
27933040-2	2016	A known important factor in this microbial competition is the ratio of available electron donor and elector acceptor, here expressed as Ac/N ratio (acetate/nitrate-nitrogen).	Nitrogen	164-172	apoptotic chromatin condensation inducer 1	Homo sapiens	136-140
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	33-41	Opt2p	Saccharomyces cerevisiae S288C	106-110
9328566-2	1997	Proteinase 3, a serine protease with an apparent molecular mass of 29 kDa, was extracted with Triton X-100 from the azurophilic granule fraction of neutrophils after nitrogen bomb cavitation and Percoll gradient centrifugation.	Nitrogen	166-174	proteinase 3	Homo sapiens	0-12
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	33-41	allantoate permease	Saccharomyces cerevisiae S288C	112-116
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	83-91	Opt2p	Saccharomyces cerevisiae S288C	106-110
28679684-6	2017	We identified new targets of the nitrogen regulation and four transporters of poor nitrogen sources-Put4, Opt2, Dal5, and Ptr2-that rapidly decrease in abundance.	Nitrogen	83-91	allantoate permease	Saccharomyces cerevisiae S288C	112-116
27655909-0	2016	N-Glycosylation influences transport, but not cellular trafficking, of a neuronal amino acid transporter SNAT1.	Nitrogen	0-1	solute carrier family 38 member 1	Homo sapiens	105-110
27655909-7	2016	Taken together, these results suggest that SNAT1 is an N-glycosylated protein with three de novo glycosylation sites and N-glycosylation of SNAT1 may play an important role in the transport of substrates across the cell membrane.	Nitrogen	44-45	solute carrier family 38 member 1	Homo sapiens	140-145
9352200-6	1997	Conserved ZPC domains and motifs present in the Xenopus sequence included a signal peptide sequence, an N-linked glycosylation site, and 12 aligned Cys residues.	Nitrogen	104-105	zona pellucida glycoprotein 3	Homo sapiens	10-13
27655909-7	2016	Taken together, these results suggest that SNAT1 is an N-glycosylated protein with three de novo glycosylation sites and N-glycosylation of SNAT1 may play an important role in the transport of substrates across the cell membrane.	Nitrogen	55-56	solute carrier family 38 member 1	Homo sapiens	43-48
27560450-5	2016	Consistently, the inhibition of the Arg/N-end rule pathway with PCA significantly elevated levels of MAPT and huntingtin aggregates, accompanied by increased numbers of LC3 and SQSTM1 puncta.	Nitrogen	40-41	microtubule associated protein tau	Homo sapiens	101-105
28731262-4	2017	We observed that pretreatment with GFA attenuated cisplatin-induced elevations in blood urea nitrogen and creatinine levels and histopathological injury induced by cisplatin.	Nitrogen	93-101	glutamine fructose-6-phosphate transaminase 1	Mus musculus	35-38
28811481-3	2017	Earlier, we had demonstrated an LIF neuron by a novel 4-terminal impact ionization based n+/p/n+ with an extended gate (gated-INPN) device by physics simulation.	Nitrogen	89-91	LIF interleukin 6 family cytokine	Homo sapiens	32-35
28811481-3	2017	Earlier, we had demonstrated an LIF neuron by a novel 4-terminal impact ionization based n+/p/n+ with an extended gate (gated-INPN) device by physics simulation.	Nitrogen	94-96	LIF interleukin 6 family cytokine	Homo sapiens	32-35
9234685-11	1997	High-level MEP2 transcription requires at least one of the two GATA family factors Gln3p and Nil1p, which are involved in transcriptional activation of many other nitrogen-regulated genes.	Nitrogen	163-171	Gat1p	Saccharomyces cerevisiae S288C	93-98
28614619-1	2017	A RhII -catalyzed direct and stereospecific N-H- and N-alkyl aziridination of olefins is reported that uses hydroxylamine-O-sulfonic acids as inexpensive, readily available, and nitro group-free aminating reagents.	Nitrogen	44-45	Rh blood group D antigen	Homo sapiens	2-6
27539975-7	2016	The findings increased the number of known N-glycosylation sites in the milk from dairy animal species, revealed the complexity of the MFGM glycoproteome, and provided useful information to further explore the mechanism of MFGM glycoproteins biosynthesis among the studied mammals.	Nitrogen	43-44	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	223-227
27658775-1	2016	Insulin-like growth factor-binding protein-3 (IGFBP3) is an N-linked glycosylated, phosphorylated protein, which has been reported to regulate cancer progression and metastasis.	Nitrogen	60-61	insulin like growth factor binding protein 3	Homo sapiens	0-44
27658775-1	2016	Insulin-like growth factor-binding protein-3 (IGFBP3) is an N-linked glycosylated, phosphorylated protein, which has been reported to regulate cancer progression and metastasis.	Nitrogen	60-61	insulin like growth factor binding protein 3	Homo sapiens	46-52
27720171-1	2016	New composite matrices have been suggested for the analysis of mixtures of different synthetic organic compounds (N-containing heterocycles and erectile dysfunction drugs) by thin layer chromatography/matrix-assisted laser desorption ionization time-of-flight mass spectrometry (TLC/MALDI-TOF).	Nitrogen	0-1	FEZ family zinc finger 2	Homo sapiens	289-292
28287721-1	2017	The synthesis of inorganic N-P(III)-Ch-based macrocycles [-PhP-NMe-PPh-Ch-]2 (8Ch; Ch = S, Se) is presented by incorporating two nitrogen, two chalcogen, and four phosphorus atoms.	Nitrogen	129-137	enolase 1	Homo sapiens	67-70
28576849-11	2017	Treatment with kifunensine, an inhibitor of complex-type N-glycosylation, weakened the binding of Gal-1 and Gal-3 to these interactors and prevented lattice formation.	Nitrogen	57-58	galectin 1	Homo sapiens	98-103
9268676-7	1997	In liquid nitrogen PZP can be maintained in native dimeric form with intact thiolester for many years.	Nitrogen	10-18	PZP alpha-2-macroglobulin like	Homo sapiens	19-22
28584151-6	2017	Resistance mapped to the loss of multiple potential N-linked glycosylation sites in gp120, suggesting that inhibition is due to steric hindrance of CD4-binding-induced conformational changes.	Nitrogen	52-53	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	84-89
28186328-0	2017	Site-specific monitoring of N-Glycosylation profiles of a CTLA4-Fc-fusion protein from the secretory pathway to the extracellular environment.	Nitrogen	28-29	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	58-63
28592651-8	2017	Based on these approaches, we were able to validate ARO1, PDC1, CPS1, ASI2, LYP1, and ALP1 allelic variants underlying nitrogen consumption differences between strains, providing evidence of many genes with small phenotypic effects.	Nitrogen	119-127	Asi2p	Saccharomyces cerevisiae S288C	70-74
27629250-2	2016	Furthermore, the coupling reaction between the aryllithium compounds and aryl ammonium salts proceeded under mild conditions with C-N bond cleavage in the presence of a [Pd(PPh3 )2 Cl2 ] catalyst.	Nitrogen	132-133	protein phosphatase 4 catalytic subunit	Homo sapiens	173-177
27768707-6	2016	Because defective protein N- or O-glycosylation upregulates transcription of PMT genes, it appears that Dom34-mediated specific translational upregulation of the PMT transcripts optimizes cellular responses to glycostress.	Nitrogen	26-27	ribosome dissociation factor DOM34	Saccharomyces cerevisiae S288C	104-109
9199331-2	1997	Recessive mutations at four unlinked loci, named PAL1 to PAL4, were isolated which prevent alkaline proteinase derepression under conditions of carbon and nitrogen limitation at pH 6.8.	Nitrogen	155-163	Pal1p	Saccharomyces cerevisiae S288C	49-53
27777973-5	2016	In diabetic mice, chemical inhibition of MDM2 with Nutlin-3a led to reduction in the number of podocytes, increased blood urea nitrogen, and increased mortality.	Nitrogen	127-135	transformed mouse 3T3 cell double minute 2	Mus musculus	41-45
28452221-3	2017	Multiple distinguishable SERS band shifts were observed and displayed a linear relationship with 15N content, because of the substitution of "light" nitrogen by "heavier" 15N stable isotope.	Nitrogen	149-157	seryl-tRNA synthetase 1	Homo sapiens	25-29
9217258-3	1997	Fractionation of PARP on Con A-Sepharose revealed that the majority (80 to 90%) of the PARP fraction did not bind to Con A and was composed of the parpA alpha gene product that contains repeats of -Glu-Pro-Pro-Thr- (GPEET-PARP) and that lacks an N-glycosylation site.	Nitrogen	246-247	collagen type XI alpha 2 chain	Homo sapiens	87-91
27667798-0	2016	Nitrogen, Phosphorus, and Fluorine Tri-doped Graphene as a Multifunctional Catalyst for Self-Powered Electrochemical Water Splitting.	Nitrogen	0-8	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	35-38
27667798-3	2016	It was found that thermal decomposition of AHF provides nitrogen, phosphorus, and fluorine sources for tri-doping with N, P, and F, and simultaneously facilitates template-free formation of porous structures as a result of thermal gas evolution.	Nitrogen	56-64	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	103-106
27519006-4	2016	The micro- and macroheterogeneous basigin N-glycosylation was site-specifically glycoprofiled using Byonic with or without a background of complex peptides using Q-Exactive Orbitrap HCD-MS/MS.	Nitrogen	42-43	basigin (Ok blood group)	Homo sapiens	34-41
27711538-4	2016	The Glu451-assisted water addition on amide carbon atoms and nitrogen inversion (i.e. change of pyramidalization on the leaving nitrogen) are shown to be the rate-determining steps with the activation energies in a good agreement with the experimental results for the Leu-enkephalin hydrolysis.	Nitrogen	61-69	prodynorphin	Homo sapiens	268-282
9217258-3	1997	Fractionation of PARP on Con A-Sepharose revealed that the majority (80 to 90%) of the PARP fraction did not bind to Con A and was composed of the parpA alpha gene product that contains repeats of -Glu-Pro-Pro-Thr- (GPEET-PARP) and that lacks an N-glycosylation site.	Nitrogen	246-247	collagen type XI alpha 2 chain	Homo sapiens	87-91
27711538-4	2016	The Glu451-assisted water addition on amide carbon atoms and nitrogen inversion (i.e. change of pyramidalization on the leaving nitrogen) are shown to be the rate-determining steps with the activation energies in a good agreement with the experimental results for the Leu-enkephalin hydrolysis.	Nitrogen	128-136	prodynorphin	Homo sapiens	268-282
9217258-5	1997	The minor Con-A-binding fraction was shown to be rich in the previously described form of PARP, encoded by the parpAbeta and/or parpB alpha genes, that contains a -Glu-Pro- repeat domain (EP-PARP) and an N-glycosylation site.	Nitrogen	204-205	collagen type XI alpha 2 chain	Homo sapiens	90-94
9192780-4	1997	Affinity-purified IgG was used to adsorb CR1 storage vesicles from the light membrane fraction (gamma-band) of nitrogen cavitates of resting PMN.	Nitrogen	111-119	complement C3b/C4b receptor 1 (Knops blood group)	Homo sapiens	41-44
27457784-9	2016	Further, incubations of M11 with recombinant P450s showed that M12 is formed via N-dealkylation of M11 by CYP3A4, CYP2C19, and CYP1A2.	Nitrogen	81-82	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	127-133
9172340-6	1997	This laboratory study shows the importance of external growth stimuli in regulating the levels and relative proportions of different microcystin variants in two strains of filamentous, nitrogen-fixing Anabaena spp.	Nitrogen	185-193	histocompatibility minor 13	Homo sapiens	210-213
27763330-0	2016	The expression of P-gp in leukemia cells is associated with cross-resistance to protein N-glycosylation inhibitor tunicamycin.	Nitrogen	88-89	phosphoglycolate phosphatase	Homo sapiens	18-22
27763330-1	2016	In P-gp-positive cell variants obtained from L1210 cells either by selection with vincristine (L1210/R) or by transfection with the human gene encoding P-gp (L1210/T), we have previously described cross-resistance to tunicamycin (TNM), a protein N-glycosylation inhibitor.	Nitrogen	231-232	phosphoglycolate phosphatase	Homo sapiens	152-156
9210490-5	1997	All three N-glycosylation mutants of DPPIV showed a reduced half-life, as well as differing degrees of inhibition of the processing of their N-glycans.	Nitrogen	10-11	dipeptidylpeptidase 4	Rattus norvegicus	37-42
9202747-4	1997	Expression of rat acetyltransferases responsible for acetylation of the nitrogen and the oxygen of arylamine derivatives (i.e., acetyltransferases 1 and 2) in bacterial cells has now permitted experiments which demonstrate that these enzymes exhibit good affinities for and N-acetylation of the endogenous arylalkylamines derived from tryptophan, i.e., tryptamine, 5-hydroxytryptamine (serotonin) and 5-methoxytryptamine, the immediate metabolic precursor of melatonin.	Nitrogen	72-80	N-acetyltransferase 8	Rattus norvegicus	128-154
27294358-4	2016	Also observed in this study, however, was increased N-sulphation detected by antibody 10E4 indicating that not only 6-O sulphation but also N-sulphation may contribute to increased RTK cell signalling in mammary tumours.	Nitrogen	52-53	ret proto-oncogene	Homo sapiens	181-184
27527599-6	2016	Mer-KO mice developed severe glomerulonephritis, with significantly decreased survival and increased blood urea nitrogen levels compared with WT mice given the same treatment.	Nitrogen	112-120	MER proto-oncogene tyrosine kinase	Mus musculus	0-3
27569420-1	2016	The synthesis of a cobalt dihydrogen Co(I)-(H2) complex prepared from a Co(I)-(N2) precursor supported by a monoanionic pincer bis(carbene) ligand, (Mes)CCC ((Mes)CCC = bis(mesityl-benzimidazol-2-ylidene)phenyl), is described.	Nitrogen	78-82	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	37-42
27569420-1	2016	The synthesis of a cobalt dihydrogen Co(I)-(H2) complex prepared from a Co(I)-(N2) precursor supported by a monoanionic pincer bis(carbene) ligand, (Mes)CCC ((Mes)CCC = bis(mesityl-benzimidazol-2-ylidene)phenyl), is described.	Nitrogen	78-82	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	72-77
27617369-0	2016	Nitrogen regulates CRY1 phosphorylation and circadian clock input pathways.	Nitrogen	0-8	cryptochrome circadian regulator 1	Homo sapiens	19-23
27617369-2	2016	Our study indicated that low nitrogen increases the NADPH/NADP(+) and ATP/AMP ratios which affect adenosine monophosphate-activated protein kinase (AMPK) activity and phosphorylation and abundance of nuclear CRY1 protein.	Nitrogen	29-37	cryptochrome circadian regulator 1	Homo sapiens	208-212
9094673-0	1997	Human immunodeficiency virus type 1 vpr gene induces phenotypic effects similar to those of the DNA alkylating agent, nitrogen mustard.	Nitrogen	118-126	Vpr	Human immunodeficiency virus 1	36-39
27337957-1	2016	THY1 (CD90) is a 25-37-kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored cell surface protein.	Nitrogen	35-36	Thy-1 cell surface antigen	Homo sapiens	0-4
27337957-1	2016	THY1 (CD90) is a 25-37-kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored cell surface protein.	Nitrogen	35-36	Thy-1 cell surface antigen	Homo sapiens	6-10
9094673-3	1997	We previously reported that Vpr mimicked some of the effects of a DNA alkylating agent known as nitrogen mustard (HN2).	Nitrogen	96-104	Vpr	Human immunodeficiency virus 1	28-31
9094673-3	1997	We previously reported that Vpr mimicked some of the effects of a DNA alkylating agent known as nitrogen mustard (HN2).	Nitrogen	96-104	MT-RNR2 like 2 (pseudogene)	Homo sapiens	114-117
27468431-10	2016	Interestingly, in the N-kappaCN/betaCN mixtures, the sugar moieties of N-kappaCN oligomers seem to organize on the mixed micelles surface in a manner similar to the organization of kappaCN in milk casein micelles.	Nitrogen	22-23	casein beta	Homo sapiens	32-38
9176120-2	1997	We here describe the expression in chinese hamster ovary (CHO) cells of rat CD59 and a modified rat CD59 in which an N-glycosylation site at Asn-16 has been deleted by point mutation.	Nitrogen	117-118	CD59 molecule	Rattus norvegicus	100-104
27695788-0	2016	Cloning of oligopeptide transport carrier PepT1 and comparative analysis of PepT1 messenger ribonucleic acid expression in response to dietary nitrogen levels in yak () and indigenous cattle () on the Qinghai-Tibetan plateau.	Nitrogen	143-151	solute carrier family 15 member 1	Bos taurus	76-81
9385561-7	1997	The CD28 model was used to map surface residues, N-linked glycosylation sites, and to compare residue conservation in CD28 and CD152.	Nitrogen	49-50	CD28 molecule	Homo sapiens	4-8
27214821-14	2016	An aberrant N-glycosylation causing a recessive or transient antithrombin deficiency is a new form of thrombophilia.	Nitrogen	12-13	serpin family C member 1	Homo sapiens	61-73
27002602-8	2016	Docking indicated that the N-containing rings of OME possibly could interact with the iron atom of the heme for S-OME in CYP17A1 and S- and R-OME in CYP21A2.	Nitrogen	27-28	cytochrome P450 family 21 subfamily A member 2	Homo sapiens	149-156
27427963-2	2016	These pathways share a highly conserved regulatory molecule, beta-catenin, which functions as both a structural component of E-cadherin junctions and as a co-transcriptional activator of the Wnt/beta-catenin signaling pathway, whose target is the N-glycosylation-regulating gene, DPAGT1.	Nitrogen	247-248	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Canis lupus familiaris	280-286
9385561-8	1997	The location of N-linked glycosylation sites in CD28/CD152 restricts the surface area available for binding.	Nitrogen	16-17	CD28 molecule	Homo sapiens	48-52
9079715-3	1997	The cDNA for alpha-tectorin predicts a protein of 239,034 Da with 33 potential N-glycosylation sites, and that of beta-tectorin a smaller protein of 36,074 Da with 4 consensus N-glycosylation sites.	Nitrogen	6-7	tectorin alpha	Mus musculus	13-27
9079715-3	1997	The cDNA for alpha-tectorin predicts a protein of 239,034 Da with 33 potential N-glycosylation sites, and that of beta-tectorin a smaller protein of 36,074 Da with 4 consensus N-glycosylation sites.	Nitrogen	79-80	tectorin alpha	Mus musculus	13-27
27182630-2	2016	The intermolecular potential between Az and N2, used for the simulations, was determined from MP2/6-31+G* ab initio calculations.	Nitrogen	44-46	tryptase pseudogene 1	Homo sapiens	94-102
9083490-1	1997	Use of automated synthesis led to the discovery of several 6-membered nitrogen heterocycles as replacements for the N-isoxazolyl substituent present in the 1-naphthalenesulfonamides endothelin-A (ETA) antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesu lfo namides (BMS 182874).	Nitrogen	70-78	endothelin receptor type A	Rattus norvegicus	182-194
9083490-1	1997	Use of automated synthesis led to the discovery of several 6-membered nitrogen heterocycles as replacements for the N-isoxazolyl substituent present in the 1-naphthalenesulfonamides endothelin-A (ETA) antagonist 5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesu lfo namides (BMS 182874).	Nitrogen	70-78	endothelin receptor type A	Rattus norvegicus	196-199
27321996-5	2016	We have used ChIP-chip analysis, transcriptional profiling of an activated Ppr1 protein, bioinformatics, and nitrogen utilization studies to establish that in Candida albicans the zinc cluster transcription factor Ppr1 controls this allantoin catabolism regulon.	Nitrogen	109-117	Ppr1p	Saccharomyces cerevisiae S288C	214-218
9083490-2	1997	In each of these heterocycles, a small substituent such as halogen para to the position of attachment to the sulfonamide nitrogen atom was found to be advantageous for ETA receptor affinity.	Nitrogen	121-129	endothelin receptor type A	Rattus norvegicus	168-171
9056417-0	1997	Defectively N-glycosylated and non-O-glycosylated aminopeptidase N (CD13) is normally expressed at the cell surface and has full enzymatic activity.	Nitrogen	12-13	alanyl aminopeptidase, membrane	Homo sapiens	50-66
27299373-3	2016	The calculations predict that the triple bond in HC2H is quite different from the triple bond in N2, with HCN being an intermediate case but closer to N2 than HC2H.	Nitrogen	97-99	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	106-109
9056417-0	1997	Defectively N-glycosylated and non-O-glycosylated aminopeptidase N (CD13) is normally expressed at the cell surface and has full enzymatic activity.	Nitrogen	12-13	alanyl aminopeptidase, membrane	Homo sapiens	68-72
9040103-7	1997	Complexation of cisplatin with alginates, especially AL-1, inhibited the accumulation of Pt in the kidneys and reduced blood urea nitrogen elevation by cisplatin.	Nitrogen	130-138	ephrin A5	Mus musculus	53-57
27367163-6	2016	An in-house synthesized N-glycinated lyso-Gb3 derivative was used for the internal standard.	Nitrogen	24-25	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	42-45
28370891-1	2017	Essentials The impact of N-linked glycosylation on ADAMTS-13 function has not been fully explored.	Nitrogen	25-26	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	51-60
28370891-10	2017	Using truncated ADAMTS-13, we demonstrated that this was attributable to loss of sialic acid from the glycans in the metalloprotease domain and an effect of N-linked glycosylation in the TSP2 through to CUB domains.	Nitrogen	157-158	thrombospondin 2	Homo sapiens	187-191
26803519-5	2016	The T/N ratio of the CPE expression level was correlated with the updated survival data from TLCN in 2015.	Nitrogen	6-7	carboxypeptidase E	Homo sapiens	21-24
26803519-6	2016	The CPE expression level in the 120 HCC patients was divided into three groups according to the T/N ratio: &lt;1, &gt;=1 and &lt;=2, and &gt;2, respectively.	Nitrogen	98-99	carboxypeptidase E	Homo sapiens	4-7
27374441-9	2016	The DNMT1, DNMT3a and DNMT3b levels in the CCI+NS group were increased significantly compared with that in the sham+NS group on the 14th day after surgery (all P&lt;0.05).	Nitrogen	47-49	DNA methyltransferase 1	Rattus norvegicus	4-9
9037234-9	1997	RESULTS: Administration of GH significantly improved the cumulative nitrogen balance, ameliorated the gross inflammation score, and decreased intestinal myeloperoxidase activity.	Nitrogen	68-76	gonadotropin releasing hormone receptor	Rattus norvegicus	27-29
27258556-1	2016	It has been found that 2-bromo-1,8-bis(dimethylamino)naphthalene on sequential treatment with n-BuLi and 2 equiv of the same or different aryl(hetaryl) cyanide as a result of [2 + 2 + 2] nucleophilic cascade annulation produces 10-dimethylaminobenzo[h]quinazolines, as yet unknown NMe2/-N  analogues of the proton sponge.	Nitrogen	10-11	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	281-285
27306501-1	2016	N2 fixation should be a critical process in the nitrogen-poor surface water of the eastern Mediterranean Sea.	Nitrogen	0-2	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	105-108
8999950-3	1997	The Kv1.3 protein expressed in vaccinia virus-infected cells and its purified counterpart are both modified by a approximately 2-kDa core-sugar moiety, most likely at a conserved N-glycosylation site in the external S1-S2 loop; absence of the sugar does not alter the biophysical properties of the channel nor does it affect expression levels.	Nitrogen	179-180	potassium voltage-gated channel subfamily A member 3	Homo sapiens	4-9
27306501-1	2016	N2 fixation should be a critical process in the nitrogen-poor surface water of the eastern Mediterranean Sea.	Nitrogen	48-56	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	105-108
26994845-4	2016	Furthermore, the lead compounds were evaluated for CYP1A1 mediated metabolism, showing N-hydroxylated metabolites, which have potential of DNA adduct formation and cause cancerous cell death.	Nitrogen	87-88	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	51-57
8941718-0	1996	L273S missense substitution in human lysosomal acid lipase creates a new N-glycosylation site.	Nitrogen	73-74	lipase A, lysosomal acid type	Homo sapiens	37-58
26745792-2	2016	The paper reported a facile synthesis of nitrogen-doped multiple graphene aerogel/gold nanostar (termed as N-doped MGA/GNS) and its use as the electrochemical sensing platform for detection of double stranded (dsDNA).	Nitrogen	41-49	glucosamine (N-acetyl)-6-sulfatase	Homo sapiens	119-122
26976442-7	2016	Here, we identify a serine/threonine-rich (Gln3477-493) region required for effective cytoplasmic Gln3-Myc(13) sequestration in excess nitrogen.	Nitrogen	135-143	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	103-106
8941718-7	1996	Furthermore, deglycosylation of normal LAL reduced the acid hydrolase activity towards both tri-oleyl glycerol and cholesteryl oleate by 50%, strongly suggesting that N-linked carbohydrate residues are important for optimal catalytic activity.	Nitrogen	167-168	lipase A, lysosomal acid type	Homo sapiens	39-42
26906474-4	2016	A hydroxyethylaminopropyl side chain on the lactam nitrogen of two halogenated indenoisoquinoline Top1 inhibitors was found to also impart inhibitory activity against tyrosyl DNA phosphodiesterases 1 and 2 (TDP1 and TDP2), which are enzymes that participate in the repair of DNA damage induced by Top1 poisons.	Nitrogen	51-59	tyrosyl-DNA phosphodiesterase 2	Homo sapiens	216-220
15299564-17	1996	For the first time hydrogen bonds were observed between the main-chain peptide N and O atoms of the complementarity-determining region CDR2 and CDR3 segments of both monomers.	Nitrogen	79-80	cerebellar degeneration related protein 2	Homo sapiens	135-139
26476268-5	2016	Remarkable glycosylation pattern changes for a peculiar 50kDa protein, i.e., the N-linked brain nucleotide pyrophosphatase-5 were evidenced, with decreased N-glycosylation in the presymptomatic and symptomatic mutant mice.	Nitrogen	81-82	polymerase (DNA directed), delta 2, regulatory subunit	Mus musculus	56-61
26476268-7	2016	Our findings indicate that there is a causal link between the amount of Mecp2 and the N-glycosylation of NPP-5.	Nitrogen	86-87	methyl CpG binding protein 2	Mus musculus	72-77
15299564-17	1996	For the first time hydrogen bonds were observed between the main-chain peptide N and O atoms of the complementarity-determining region CDR2 and CDR3 segments of both monomers.	Nitrogen	79-80	CDR3	Homo sapiens	144-148
26628609-1	2016	Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis.	Nitrogen	10-18	hypothetical protein	Arabidopsis thaliana	103-123
8798755-1	1996	Cloning of the cDNA encoding a novel human protein- tyrosine phosphatase (PTP) called islet cell antigen-related PTP (IAR) predicts a receptor-like molecule with an extracellular domain of 614 amino acids containing a hydrophobic signal peptide, one potential N-glycosylation site, and an RGDS peptide which is a possible adhesive recognition sequence.	Nitrogen	17-18	ral guanine nucleotide dissociation stimulator	Homo sapiens	289-293
26628609-1	2016	Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis.	Nitrogen	10-18	hypothetical protein	Arabidopsis thaliana	125-127
26889565-1	2016	In this review we focus on the catalytic removal of a series of N-containing exhaust gases with various valences, including nitriles (HCN, CH3CN, and C2H3CN), ammonia (NH3), nitrous oxide (N2O), and nitric oxides (NO(x)), which can cause some serious environmental problems, such as acid rain, haze weather, global warming, and even death.	Nitrogen	64-65	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	134-137
26853155-0	2016	Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2.	Nitrogen	33-34	endogenous retrovirus group FRD member 1, envelope	Homo sapiens	141-151
26853155-3	2016	We constructed expression plasmids of wild-type and 21 single-amino-acid substitution mutants of syncytin-2, including 10 N-glycosylation sites individually silenced by mutagenizing N to Q, 1 naturally occurring single-nucleotide polymorphism (SNP) N118S that introduced an N-glycosylation site, and another 10 non-synonymous SNPs located within important functional domains.	Nitrogen	182-183	endogenous retrovirus group FRD member 1, envelope	Homo sapiens	97-107
26882001-0	2016	CBr4 Mediated Oxidative C-N Bond Formation: Applied in the Synthesis of Imidazo[1,2-alpha]pyridines and Imidazo[1,2-alpha]pyrimidines.	Nitrogen	26-27	carbonyl reductase 4	Homo sapiens	0-4
25676153-5	2016	Nitrogen starvation caused a significant decrease both in transcript levels and in NR, NiR, GS, and GOGAT activities.	Nitrogen	0-8	ferredoxin--nitrite reductase, chloroplastic	Triticum aestivum	87-90
25676153-8	2016	The results of our study highlight the differential effects between the type and the amount of nitrogen salts on NR, NiR, GS, and GOGAT activities in wheat seedlings while potassium nitrate being more effective.	Nitrogen	95-103	ferredoxin--nitrite reductase, chloroplastic	Triticum aestivum	117-120
26773662-3	2016	In this work, we investigated a multifunctional carbohydrate-based drug candidate, tri-butanoylated N-acetyl-D-galactosamine analog (3,4,6-O-Bu3GalNAc) that induced cartilage tissue production by human mesenchymal stem cells (hMSCs) and human OA chondrocytes by modulating Wnt/beta-catenin signaling activity.	Nitrogen	100-101	catenin beta 1	Homo sapiens	277-289
26553504-1	2016	We perform here enhanced sampling simulations of N-terminally acetylated human alpha-synuclein, an intrinsically disordered protein involved in Parkinson"s disease.	Nitrogen	49-50	synuclein alpha	Homo sapiens	79-94
26637370-4	2016	Downregulation of these critical survival pathways is shown to be due to 2-DG"s interference with N-linked glycosylation, leading to alterations in VEGFR2 (and downstream signaling) as well as induction of endoplasmic reticulum (ER) stress, GSK3beta activation, and apoptosis.	Nitrogen	98-99	glycogen synthase kinase 3 beta	Mus musculus	241-249
26700190-3	2016	In both systems, the initial interaction occurs through unconventional CH(delta+)   N ionic hydrogen bonds between the hydrogen atoms of the naphthalene cation and the lone pair of electrons on the N atom of the HCN or the CH3CN molecule.	Nitrogen	84-85	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	212-215
26767057-9	2016	Furthermore, KAT2B was associated with AAA diameter (r = 0.382, P &lt; 0.05), and KAT3B, KAT6A, and KAT6B correlated negatively with blood urea nitrogen (r = -0.403, -0.408, -0.478, P &lt; 0.05).	Nitrogen	144-152	lysine acetyltransferase 6B	Homo sapiens	100-105
26467158-8	2016	Point mutations at two N-glycosylation sites (Asn(153) and Asn(223)) abolish the bisecting GlcNAc modification on BACE1.	Nitrogen	23-24	beta-site APP cleaving enzyme 1	Mus musculus	114-119
26653175-5	2016	SL-biosynthesis (max1-1) and SL-insensitive (atd14-1) mutants showed altered responses to nitrogen deficient in comparison with wild-type (WT) plants.	Nitrogen	90-98	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	17-21
26653175-6	2016	Nitrogen deficient conditions led to alterations in the expression levels of SL biosynthesis genes (MAX3 and MAX4).	Nitrogen	0-8	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	100-104
26653175-6	2016	Nitrogen deficient conditions led to alterations in the expression levels of SL biosynthesis genes (MAX3 and MAX4).	Nitrogen	0-8	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	109-113
27642825-0	2016	Reducing agricultural nitrogen inputs in the German Baltic Sea catchment - trends and policy options.	Nitrogen	22-30	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	59-62
27642825-3	2016	The nitrogen surpluses are transferred to a nutrient emission model to simulate nitrogen emissions, in-stream retention and resulting riverine loads to the sea until 2021.	Nitrogen	4-12	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	156-159
26681516-2	2015	Studies in yeast and human cells have shown that nitrogen/amino acid starvation signals act through Npr2/Npr3 and the small GTPases Gtr1/Gtr2 (Rags in humans) to inhibit TORC1.	Nitrogen	49-57	natriuretic peptide receptor 3	Homo sapiens	105-109
26681516-2	2015	Studies in yeast and human cells have shown that nitrogen/amino acid starvation signals act through Npr2/Npr3 and the small GTPases Gtr1/Gtr2 (Rags in humans) to inhibit TORC1.	Nitrogen	49-57	Ras related GTP binding C	Homo sapiens	137-141
26486317-4	2015	We probed different substitutions at the indazole 5-position and at the piperidine-nitrogen to obtain potent ATP-competitive GSK-3beta inhibitors with good cell activity.	Nitrogen	83-91	glycogen synthase kinase 3 beta	Mus musculus	125-134
26451472-0	2015	Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction.	Nitrogen	29-37	thioredoxin	Homo sapiens	0-11
26451472-0	2015	Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction.	Nitrogen	29-37	thioredoxin	Homo sapiens	96-107
26451472-0	2015	Thioredoxin Cross-Linking by Nitrogen Mustard in Lung Epithelial Cells: Formation of Multimeric Thioredoxin/Thioredoxin Reductase Complexes and Inhibition of Disulfide Reduction.	Nitrogen	29-37	peroxiredoxin 5	Homo sapiens	108-129
26154505-2	2015	In order to examine the impact of glycosyltransferase expression on the N-glycosylation of recombinant erythropoietin (rEPO), a human alpha2,6-sialyltransferase (ST6Gal1) was expressed in Chinese hamster ovary (CHO-K1) cells.	Nitrogen	72-73	erythropoietin	Rattus norvegicus	119-123
26910983-0	2015	[Distribution Characteristics of Urea and Constitution of Dissolved Nitrogen in the Bohai Sea and the Huanghai Sea in Spring].	Nitrogen	68-76	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	90-93
26531304-1	2015	Changes in N-NO2 bond strength, ring strain energy and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX were investigated using DFT-B3LYP and MP2(full) methods with the 6-311++G(2df,2p) and aug-cc-pVTZ basis sets.	Nitrogen	154-162	tryptase pseudogene 1	Homo sapiens	257-260
26478188-7	2015	We also revealed that these effects of dimeric CMP-Ang1 were affected by specified N-glycosylation in its fibrinogen-like domain.	Nitrogen	83-84	matrilin 1	Homo sapiens	47-50
26410663-3	2015	We have previously identified a nitrogen-containing honokiol derivative (3-acetylamino-4"-O-methylhonokiol, AMH) as a high efficient modulator of GABAA receptors.	Nitrogen	32-40	anti-Mullerian hormone	Homo sapiens	108-111
26011613-2	2015	We estimated the effects of climate change and possible future scenarios of agricultural changes on the phosphorus and nitrogen loading to the Baltic Sea from Finnish catchments.	Nitrogen	119-127	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	150-153
25904701-8	2015	Multiple logistic regression and receiver-operating characteristics analysis further showed that urine VIM mRNA is the best predictive parameter of renal fibrosis compared with estimated glomerular filtration rate, serum creatinine, and blood urea nitrogen.	Nitrogen	248-256	vimentin	Homo sapiens	103-106
26224316-6	2015	N-glycosylation of JAM-A is required for the protein"s ability to reinforce barrier function and contributes to Rap1 activity.	Nitrogen	0-1	RAP1A, member of RAS oncogene family	Homo sapiens	112-116
26252912-8	2015	In solid nitrogen, HCN monomers are observed besides SHCN, indicating efficient escape of atomic sulfur out of the matrix cage occupied by the precursor.	Nitrogen	9-17	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	19-22
26221031-6	2015	This affected the outcome of processing of a substrate containing a nitrogen mustard-like ICL two nucleotides in the duplex region because FAN1, unlike EXO1 and FEN1, incised the substrate predominantly beyond the ICL and, therefore, failed to release the 5" flap.	Nitrogen	68-76	exonuclease 1	Homo sapiens	152-156
26221031-6	2015	This affected the outcome of processing of a substrate containing a nitrogen mustard-like ICL two nucleotides in the duplex region because FAN1, unlike EXO1 and FEN1, incised the substrate predominantly beyond the ICL and, therefore, failed to release the 5" flap.	Nitrogen	68-76	flap structure-specific endonuclease 1	Homo sapiens	161-165
26361580-7	2015	When we assessed the nine articles on Asian subjects, the difference of CIMT-SDS between the two groups was invariably significant only for N (p = 0.015).	Nitrogen	140-141	CIMT	Homo sapiens	72-76
28562630-6	2017	N-acetylation reduces considerably the rate of aggregation of WT alpha-Synuclein.	Nitrogen	0-1	synuclein alpha	Homo sapiens	65-80
28412361-5	2017	INCB14943 binds to heme iron in IDO1 protein through the oxime nitrogen.	Nitrogen	63-71	indoleamine 2,3-dioxygenase 1	Homo sapiens	32-36
28412361-7	2017	Comparing with the other reported inhibitors, the oxime nitrogen and halogen bond interaction are identified as the unique features of INCB14943 among the IDO1 inhibitors.	Nitrogen	56-64	indoleamine 2,3-dioxygenase 1	Homo sapiens	155-159
28534482-3	2017	We show that Fbs1 is able to bind diverse types of N-linked glycomolecules; however, wild-type Fbs1 preferentially binds high-mannose-containing glycans.	Nitrogen	51-52	fibrosin	Homo sapiens	13-17
28534482-3	2017	We show that Fbs1 is able to bind diverse types of N-linked glycomolecules; however, wild-type Fbs1 preferentially binds high-mannose-containing glycans.	Nitrogen	51-52	fibrosin	Homo sapiens	95-99
28351617-0	2017	Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion.	Nitrogen	97-98	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	26-72
28351617-0	2017	Interaction of FAM5C with UDP-glucose:glycoprotein glucosyltransferase 1 (UGGT1): Implication of N-glycosylation in FAM5C secretion.	Nitrogen	97-98	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	74-79
28199080-2	2017	Previous characterization of a cytochrome P450 (CYP)-rich GA biosynthetic operon found in many symbiotic, nitrogen-fixing rhizobia led to the elucidation of bacterial GA biosynthesis and implicated GA9 as the final product.	Nitrogen	106-114	peptidylprolyl isomerase G	Homo sapiens	48-51
27757559-5	2017	5T4 molecules are 72 kD, heavily N-glycosylated proteins with several leucine-rich repeats which are often associated with protein-protein interactions.	Nitrogen	33-34	trophoblast glycoprotein	Homo sapiens	0-3
28339983-1	2017	Glutamine synthetase (GS) is an important enzyme for nitrogen assimilation, and GS2, encoded by GLN2, is the only plastid-type GS in Arabidopsis thaliana.	Nitrogen	53-61	hypothetical protein	Arabidopsis thaliana	0-20
28339983-1	2017	Glutamine synthetase (GS) is an important enzyme for nitrogen assimilation, and GS2, encoded by GLN2, is the only plastid-type GS in Arabidopsis thaliana.	Nitrogen	53-61	hypothetical protein	Arabidopsis thaliana	22-24
28316799-1	2017	In the title cobalt(II) coordination polymer with isobutyrate ligands, {[Co{CH(CH3)2CO2}2(H2O)] H2O} n , the Co2+ ion is hexa-coordinated in a slightly distorted octa-hedral coordination environment defined by two O atoms from two bridging water mol-ecules and four O atoms from four bridging carboxyl-ate ligands.	Nitrogen	1-2	complement C2	Homo sapiens	109-112
26248643-1	2015	RGa {R=HC[C(Me)N(2,6-iPr2C6H3)]2} reacts with Sb(NMe2)3 with insertion into the Sb-N bond and elimination of RGa(NMe2)2 (2), yielding the Ga-substituted distibene R(Me2N)GaSb=SbGa(NMe2 )R (1).	Nitrogen	15-16	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	49-53
8902262-4	1996	All drugs metabolized by P450 2D6 contain a basic nitrogen atom, and a flat hydrophobic region coplanar to the oxidation site which is either 5 or 7 A away from the basic nitrogen atom.	Nitrogen	50-58	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	25-29
26135009-2	2015	Previously we reported that the formation of 3-hydroxydesloratadine, the major human metabolite of desloratadine, involves three sequential reactions, namely N-glucuronidation by UGT2B10 followed by 3-hydroxylation by CYP2C8 followed by deconjugation (rapid, nonenzymatic hydrolysis of the N-glucuronide).	Nitrogen	158-159	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	179-186
8902262-4	1996	All drugs metabolized by P450 2D6 contain a basic nitrogen atom, and a flat hydrophobic region coplanar to the oxidation site which is either 5 or 7 A away from the basic nitrogen atom.	Nitrogen	171-179	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	25-29
8862453-8	1996	Compared with gamma-rays the breaks were reduced by a factor of 4 after He ions and a factor of 14 after N ions, i.e. ssb and dsb seem to be in the same range after nitrogen ions.	Nitrogen	165-173	small RNA binding exonuclease protection factor La	Homo sapiens	118-121
26218892-2	2015	The main N-demethylation metabolic mechanism of theobromine catalyzed by P450 isoenzyme 1A2 (CYP1A2) has been explored in this work using the unrestricted hybrid density functional method UB3LYP in conjunction with the LACVP(Fe)/6-31G (H, C, N, O, S, Cl) basis set.	Nitrogen	9-10	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	93-99
26218892-7	2015	Strikingly, 3-N demethylation is more favorable than 7-N demethylation due to its lower free energy barrier and 7-methylxanthine therefore is the optimum product reported for the demethylation of theobromine catalyzed by CYP1A2, which are in good agreement with the experimental observation.	Nitrogen	14-15	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	221-227
26274980-1	2015	Neutrophil cathepsin G (nCG) is a central serine protease in the human innate immune system, but the importance of its N-glycosylation remains largely undescribed.	Nitrogen	0-1	cathepsin G	Homo sapiens	11-22
8798662-0	1996	Novel sites of N-glycosylation in ROMK1 reveal the putative pore-forming segment H5 as extracellular.	Nitrogen	0-1	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	34-39
8790377-6	1996	Using a monospecific antibody to the HIV-1 gp120 natural signal peptide, we showed that calnexin associated with N-glycosylated but uncleaved gp120.	Nitrogen	113-114	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	43-48
26284094-1	2015	Glutamine synthetase (GS) catalyzes the first step at which nitrogen is brought into cellular metabolism and is also involved in the reassimilation of ammonium released by a number of metabolic pathways.	Nitrogen	60-68	LOC11405318	Medicago truncatula	0-20
26180195-3	2015	The missense mutation CLRN1(N48K), which affects a conserved N-glycosylation site in hCLRN1, is a common causative USH3 mutation among Ashkenazi Jews.	Nitrogen	25-26	clarin 1	Homo sapiens	85-91
8790377-6	1996	Using a monospecific antibody to the HIV-1 gp120 natural signal peptide, we showed that calnexin associated with N-glycosylated but uncleaved gp120.	Nitrogen	113-114	calnexin	Homo sapiens	88-96
8886603-12	1996	Taken together, these studies indicate that the N-demethylation of S-mephenytoin by human liver microsomes is catalyzed primarily by CYP2B6.	Nitrogen	48-49	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	133-139
26171609-7	2015	The two different N-glycans could, therefore, represent different maturation stages of N-glycosylation with the 25-kDa likely a precursor of the 30-40-kDa HAI-2, with the ratio of their levels roughly similar among a variety of cells.	Nitrogen	18-19	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	155-160
8887900-2	1996	We have assessed the dose-dependent effects of GH and IGF-1 treatments on nitrogen metabolism, intestinal structure, and hepatic IGF-1-messenger RNA (mRNA) expression in postoperative parenterally fed rats.	Nitrogen	74-82	gonadotropin releasing hormone receptor	Rattus norvegicus	47-49
26020100-7	2015	Our results show that anti-RhoC particles used at a low N/P ratio of 2.5/1 suppressed RhoC protein levels by 100% and 90% in SUM149 and MDA-MB-231 cells, respectively.	Nitrogen	56-57	ras homolog family member C	Homo sapiens	27-31
26020100-7	2015	Our results show that anti-RhoC particles used at a low N/P ratio of 2.5/1 suppressed RhoC protein levels by 100% and 90% in SUM149 and MDA-MB-231 cells, respectively.	Nitrogen	56-57	ras homolog family member C	Homo sapiens	86-90
26147980-1	2015	BACKGROUND: Mucopolysaccharidosis IVA (MPS IVA; Morquio A disease) is an autosomal recessive disease caused and characterized by a decreased activity of N-acetylgalactosamine-6-sulfate sulfatase (GALNS), resulting in accumulation of keratan sulfate and chondroitin-6-sulfate in tissues and secondary organ damage.	Nitrogen	8-9	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	196-201
8887900-7	1996	RESULTS: Both GH and IGF-1 attenuated body weight loss and nitrogen excretion and increased whole-body protein synthesis and spleen weight.	Nitrogen	59-67	gonadotropin releasing hormone receptor	Rattus norvegicus	14-16
25899780-5	2015	The mild activated N-doped carbon microflowers (A-NCF-4) have a hierarchically porous structure, high specific surface area (2309 m(2)  g(-1)), desirable micropore size below 1 nm, and importantly large micropore volume (0.95 cm(3)  g(-1)).	Nitrogen	19-20	neutrophil cytosolic factor 4	Homo sapiens	50-55
8888624-2	1996	In Arabidopsis seedlings, accumulation of transcripts for BiP was induced not only by inhibition of the N-glycosylation of proteins by tunicamycin but also by inhibition of the processing of N-linked glycans by castanospermine.	Nitrogen	104-105	Heat shock protein 70 (Hsp 70) family protein	Arabidopsis thaliana	58-61
25861849-3	2015	AAL recognizes both alpha1-3/1-4 and alpha1-6 fucosylation on N/O-linked glycans.	Nitrogen	62-64	adrenoceptor alpha 1D	Homo sapiens	20-45
8761309-4	1996	Nucleotide sequence analysis indicated that the Wnt-13 gene encodes the protein of 372 amino acids, including a signal peptide, two potential N-glycosylation sites and 24 cystein residues highly conserved among members of the Wnt gene family.	Nitrogen	0-1	wingless-type MMTV integration site family, member 2	Mus musculus	48-51
26039991-5	2015	We found that the protein product of an alternatively spliced Junctin isoform is N-glycosylated at a specific asparagine site that is required for interactions with specific protein partners.	Nitrogen	81-82	aspartate-beta-hydroxylase	Mus musculus	62-69
28357388-11	2017	Genetic disruption of PTC7 prevented mitophagy activation in conditions of nitrogen deprivation.	Nitrogen	75-83	type 2C protein phosphatase PTC7	Saccharomyces cerevisiae S288C	22-26
8707857-10	1996	We previously showed that the binding of two ligands to the cell surface N-acetylgalactosaminylphosphotransferase (GalNAcPTase), the monoclonal antibody 1B11 and a proteoglycan with a 250-kD core protein, results in the accumulation of phosphorylated tyrosine residues on beta-catenin, uncoupling of N-cadherin from its association with the actin containing cytoskeleton, and loss of N-cadherin function.	Nitrogen	73-74	cadherin 2	Gallus gallus	300-310
26467655-9	2017	The reductions in both nitrogen and phosphorus loads have led to large-scale alleviation of eutrophication and to a healthier Baltic Sea.	Nitrogen	23-31	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	133-136
26009801-2	2015	The nitrogen bases include the sp(3) bases NH3, NClH2, NFH2, NCl2H, NCl3, NFCl2, NF2H, NF2Cl, and NF3 and the sp bases NCNH2, NCCH3, NP, NCOH, NCCl, NCH, NCF, NCCN, and N2.	Nitrogen	4-12	neutrophil cytosolic factor 4	Homo sapiens	154-157
26024867-0	2015	GATA Factor Regulation in Excess Nitrogen Occurs Independently of Gtr-Ego Complex-Dependent TorC1 Activation.	Nitrogen	33-41	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	0-4
26024867-3	2015	Rapamycin inhibition of TorC1 elicits nuclear localization of Gln3, a GATA-family transcription activator responsible for the expression of genes encoding proteins required to transport and degrade poor nitrogen sources, e.g., proline.	Nitrogen	203-211	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	70-74
8707857-10	1996	We previously showed that the binding of two ligands to the cell surface N-acetylgalactosaminylphosphotransferase (GalNAcPTase), the monoclonal antibody 1B11 and a proteoglycan with a 250-kD core protein, results in the accumulation of phosphorylated tyrosine residues on beta-catenin, uncoupling of N-cadherin from its association with the actin containing cytoskeleton, and loss of N-cadherin function.	Nitrogen	73-74	cadherin 2	Gallus gallus	384-394
27862579-3	2017	Here, we report a patient with defects in both N- and O-glycosylation combined with a delayed vesicular transport in the GA due to mutations in TRAPPC11, a subunit of the TRAPPIII complex.	Nitrogen	47-48	trafficking protein particle complex subunit 11	Homo sapiens	144-152
8666285-4	1996	However, potential N-linked glycosylation sites which have been reported in human and rhesus Plg are not present in analogous positions in the hedgehog Plg sequence.	Nitrogen	19-20	plasminogen	Homo sapiens	93-96
26022021-12	2015	Urinary MCP-1 correlates positively with proteinuria, blood urea nitrogen level and creatinine and negatively with hemoglobin and creatinine clearance.	Nitrogen	65-73	C-C motif chemokine ligand 2	Homo sapiens	8-13
27897388-4	2017	Unexpectedly, calcium complexes ((L3-5 )CaN(SiMe3 )2 ) bearing more sterically encumbered ligands of the same type were extremely unstable and underwent C-N bond cleavage processes as a consequence of intramolecular C-H bond activation, leading to the exclusive formation of (E)-1,2-bis(8-isopropylquinol-2-yl)ethane.	Nitrogen	42-43	ribosomal protein L35	Homo sapiens	34-38
8631921-14	1996	Examination of the electrophoretic mobility of the N-linked modified protein invertase in null mutant strains indicates that Ktr1p, Ktr2p, and Yur1p are involved in N-linked glycosylation, possibly as redundant enzymes.	Nitrogen	51-52	mannosyltransferase YUR1	Saccharomyces cerevisiae S288C	143-148
25760407-5	2015	The freeze-dried GOP-1 composite hydrogel exhibited a large specific surface area, high nitrogen content, and three-dimensional network structure.	Nitrogen	88-96	C-type lectin domain containing 16A	Homo sapiens	17-22
8725147-4	1996	The deduced amino acid sequences from the mouse and human LAL had high similarity (95%) and identity (75%) including conservation of the active center motifs (G-X-S-X-G) and five potential N-glycosylation consensus sequences.	Nitrogen	189-190	lipase A, lysosomal acid type	Homo sapiens	58-61
25785825-1	2015	The palladium-catalyzed reaction of 2,3,3-trifluoroallyl esters with several types of amines afforded trifluoromethylenamines, which were formed by the addition of a nitrogen nucleophile at the C-2 position and the intramolecular construction of the trifluoromethyl group via the fluorine atom shift from the C-2 to the C-3 position.	Nitrogen	166-174	complement C2	Homo sapiens	194-197
25785825-1	2015	The palladium-catalyzed reaction of 2,3,3-trifluoroallyl esters with several types of amines afforded trifluoromethylenamines, which were formed by the addition of a nitrogen nucleophile at the C-2 position and the intramolecular construction of the trifluoromethyl group via the fluorine atom shift from the C-2 to the C-3 position.	Nitrogen	166-174	complement C2	Homo sapiens	309-312
27862459-2	2017	The reaction between 2-aminothiophenol and alpha,beta-unsaturated pyrazoleamides gave direct access to N-H-free 1,5-benzothiazepines in the presence of a chiral N,N"-dioxide/Yb(OTf)3 complex.	Nitrogen	103-104	POU class 5 homeobox 1	Homo sapiens	177-182
28046067-5	2017	beta-glucuronidase (Gusb) was identified as a protein bound to Dectin-2 and mutations of N-glycosylation sites in Gusb impaired the binding of Gusb to Dectin-2.	Nitrogen	89-90	C-type lectin domain containing 6A	Homo sapiens	63-71
28046067-5	2017	beta-glucuronidase (Gusb) was identified as a protein bound to Dectin-2 and mutations of N-glycosylation sites in Gusb impaired the binding of Gusb to Dectin-2.	Nitrogen	89-90	C-type lectin domain containing 6A	Homo sapiens	151-159
8773261-2	1996	AT1 and AT2 both correspond to G-protein-coupled receptors with seven hydrophobic transmembrane domains, several N-glycosylation sites and a potential G-protein binding site.	Nitrogen	113-114	angiotensin II receptor type 1	Homo sapiens	0-3
28531887-11	2017	Moreover, we identified Asn318 as the single N-glycosylation site of MT4-MMP.	Nitrogen	45-46	matrix metallopeptidase 17	Homo sapiens	69-76
27770224-2	2017	In this study, crucial genes like ARO8 and ARO10 of Ehrlich pathway for 2-PE synthesis and key transcription factor ARO80 in Saccharomyces cerevisiae were re-regulated using constitutive promoter; in the meantime, the effect of nitrogen source in synthetic complete (SC) medium with L-phenylalanine (L-Phe) on Aro8/Aro9 and Aro10 was investigated.	Nitrogen	228-236	aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	315-319
27572535-1	2016	Nitrogen (N) retention sensu lato refers to all processes preventing new reactive nitrogen brought into watersheds through agricultural or industrial activities to be exported by river systems to the sea.	Nitrogen	0-8	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	200-203
27959934-7	2016	DNA sequence analysis of Npr3 identified a missense mutation, Tyr209Asn, which introduced an N-linked glycosylation consensus sequence.	Nitrogen	1-2	natriuretic peptide receptor 3	Mus musculus	25-29
25504047-6	2015	This integrin-beta1 N-glycosylation pattern was correlated with higher levels of membrane-bound integrin-beta1 and also with increased binding to fibronectin.	Nitrogen	20-21	fibronectin 1	Mus musculus	146-157
25416425-0	2015	The degree of N-glycosylation affects the trafficking and cell surface expression levels of Kv1.4 potassium channels.	Nitrogen	14-15	potassium voltage-gated channel subfamily A member 4	Homo sapiens	92-97
26109997-7	2015	CIMT also correlated with age, duration of diabetes, systolic blood pressure, blood urea nitrogen, and serum creatinine.	Nitrogen	89-97	CIMT	Homo sapiens	0-4
27790664-1	2016	Co2+ ions encapsulated in nitrogen doped graphene were applied as an oxygen evolution catalyst.	Nitrogen	26-34	complement C2	Homo sapiens	0-3
8773261-2	1996	AT1 and AT2 both correspond to G-protein-coupled receptors with seven hydrophobic transmembrane domains, several N-glycosylation sites and a potential G-protein binding site.	Nitrogen	113-114	angiotensin II receptor type 2	Homo sapiens	8-11
25689485-0	2015	The expression of nitrate transporter genes reveals different nitrogen statuses of dominant diatom groups in the southern East China Sea.	Nitrogen	62-70	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	133-136
8638929-4	1996	Although no relationship was observed between the levels of CYP2B1/2 and CYP3A, ratios of CYP3A/CYP2B1 plus CYP2B2 contents were invariably higher with hepatocytes treated with N-methylated barbiturates than with the nonmethylated analogs.	Nitrogen	177-178	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	60-66
27739682-2	2016	We investigate the possibility of spin-forbidden transitions between the lowest energy electronic states with different spin multiplicities in the rubredoxin active site models [Fe(SCH3)4]n (n = 2-, 1-, 0) using nonadiabatic transition state theory (NA-TST).	Nitrogen	4-5	thiosulfate sulfurtransferase	Homo sapiens	253-256
8638929-4	1996	Although no relationship was observed between the levels of CYP2B1/2 and CYP3A, ratios of CYP3A/CYP2B1 plus CYP2B2 contents were invariably higher with hepatocytes treated with N-methylated barbiturates than with the nonmethylated analogs.	Nitrogen	177-178	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	96-102
8700170-6	1996	We find that the CBA/N defect partially impairs both B7-1 and B7-2 induction via CD40.	Nitrogen	21-22	CD40 antigen	Mus musculus	81-85
26455908-1	2016	Nitrogen permease regulator like-2(NPRL2) is a candidate tumor suppressor gene(TSG) located on chromosome 3p21.3 and deletions frequently occur in this region, leading to canceration.	Nitrogen	0-8	NPR2 like, GATOR1 complex subunit	Homo sapiens	35-40
25558770-2	2015	The distribution of products was found to be dependent on the substituent group on the nitrogen atom, the ligand on the Rh(II) center, and the solvent used.	Nitrogen	87-95	Rh blood group D antigen	Homo sapiens	120-126
25527290-0	2015	Nitrogen starvation and TorC1 inhibition differentially affect nuclear localization of the Gln3 and Gat1 transcription factors through the rare glutamine tRNACUG in Saccharomyces cerevisiae.	Nitrogen	0-8	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	91-95
25527290-3	2015	This led us to conclude that excess nitrogen-dependent down-regulation of Gln3 occurs via a second mechanism that is independent of leucine-dependent TorC1 activation.	Nitrogen	36-44	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	74-78
25527290-7	2015	Long-term nitrogen starvation and treatment of cells with the glutamine synthetase inhibitor methionine sulfoximine (Msx) also elicit nuclear Gln3 localization.	Nitrogen	10-18	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	142-146
25527290-8	2015	The sensitivity of Gln3 localization to glutamine and inhibition of glutamine synthesis prompted us to investigate the effects of a glutamine tRNA mutation (sup70-65) on nitrogen-responsive control of Gln3 and Gat1.	Nitrogen	170-178	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	201-205
9206117-0	1996	Analysis of the N-glycosylation of the serum glycoproteins defined by Con A, PHA-E, RCA1 and WGA in Chinese patients with gastrointestinal diseases.	Nitrogen	16-17	von Hippel-Lindau tumor suppressor	Homo sapiens	84-88
25527290-9	2015	We found that nuclear Gln3 localization elicited by short- and long-term nitrogen starvation; growth in a poor, derepressive medium; Msx or rapamycin treatment; or ure2Delta mutation is abolished in a sup70-65 mutant.	Nitrogen	73-81	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	22-26
25527290-12	2015	These observations demonstrate the existence of a specific nitrogen-responsive component participating in the control of Gln3 and Gat1 localization and their downstream production of nitrogenous precursors.	Nitrogen	59-67	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	121-125
25527290-14	2015	Our observations also demonstrate distinct mechanistic differences between the responses of Gln3 and Gat1 to rapamycin inhibition of TorC1 and nitrogen starvation.	Nitrogen	143-151	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	92-96
27799750-2	2016	Sodium phenylbutyrate (NaPB) is a lifesaving waste nitrogen, alternative to urea nitrogen, for individuals suffering from urea cycle disorders.	Nitrogen	51-59	NSF attachment protein beta	Homo sapiens	23-27
27318240-9	2016	SWAT provided robust measurement of occupancy at more N-glycosylation sites and with higher precision than SWATH, allowing identification of novel glycosylation sites dependent on the Ost3p and Ost6p regulatory subunits of oligosaccharyltransferase.	Nitrogen	54-55	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	184-189
8617281-5	1996	Structural chemistry of MUC1 oligosaccharides demonstrated that the cancer-associated glycoforms carry mainly sialylated trisaccharides NeuAc alpha 2-3Gal Beta 1-3GalNAc or NeuAc alpha 2-6(Gal beta l-3)GalNAc, exhibit a concomitant decrease in the ratio of GlcNAc/GalNAc, a reduction or disappearance of L-fucose, and a partial substitution of N-acetylneuraminic acid by the N-glycolylated variant.	Nitrogen	136-137	mucin 1, cell surface associated	Homo sapiens	24-28
27318240-9	2016	SWAT provided robust measurement of occupancy at more N-glycosylation sites and with higher precision than SWATH, allowing identification of novel glycosylation sites dependent on the Ost3p and Ost6p regulatory subunits of oligosaccharyltransferase.	Nitrogen	54-55	dolichyl-diphosphooligosaccharide--protein glycotransferase	Saccharomyces cerevisiae S288C	194-199
27596261-7	2016	These findings indicate that feeding of n-3 PUFA enriched diet increased IGF-1 and testosterone secretion, reduced pubertal age and improved both fresh and post-thawing semen quality in male buffalo.	Nitrogen	8-9	insulin like growth factor 1	Bos taurus	73-78
27545836-5	2016	With the increase in the number of NCF units from 1 to 3, the VS,min values outside the nitrogen atom of NCF become increasingly negative, the electric field of the lone pair of nitrogen becomes greater and causes a further increase of electron density outside the nitrogen atom and a further decrease of electron density outside the pseudo pi-hole region, resulting in a stronger pseudo pi-hole interaction.	Nitrogen	88-96	neutrophil cytosolic factor 4	Homo sapiens	35-38
27545836-5	2016	With the increase in the number of NCF units from 1 to 3, the VS,min values outside the nitrogen atom of NCF become increasingly negative, the electric field of the lone pair of nitrogen becomes greater and causes a further increase of electron density outside the nitrogen atom and a further decrease of electron density outside the pseudo pi-hole region, resulting in a stronger pseudo pi-hole interaction.	Nitrogen	88-96	neutrophil cytosolic factor 4	Homo sapiens	105-108
27545836-5	2016	With the increase in the number of NCF units from 1 to 3, the VS,min values outside the nitrogen atom of NCF become increasingly negative, the electric field of the lone pair of nitrogen becomes greater and causes a further increase of electron density outside the nitrogen atom and a further decrease of electron density outside the pseudo pi-hole region, resulting in a stronger pseudo pi-hole interaction.	Nitrogen	178-186	neutrophil cytosolic factor 4	Homo sapiens	35-38
27545836-5	2016	With the increase in the number of NCF units from 1 to 3, the VS,min values outside the nitrogen atom of NCF become increasingly negative, the electric field of the lone pair of nitrogen becomes greater and causes a further increase of electron density outside the nitrogen atom and a further decrease of electron density outside the pseudo pi-hole region, resulting in a stronger pseudo pi-hole interaction.	Nitrogen	178-186	neutrophil cytosolic factor 4	Homo sapiens	105-108
27545836-5	2016	With the increase in the number of NCF units from 1 to 3, the VS,min values outside the nitrogen atom of NCF become increasingly negative, the electric field of the lone pair of nitrogen becomes greater and causes a further increase of electron density outside the nitrogen atom and a further decrease of electron density outside the pseudo pi-hole region, resulting in a stronger pseudo pi-hole interaction.	Nitrogen	178-186	neutrophil cytosolic factor 4	Homo sapiens	35-38
27545836-5	2016	With the increase in the number of NCF units from 1 to 3, the VS,min values outside the nitrogen atom of NCF become increasingly negative, the electric field of the lone pair of nitrogen becomes greater and causes a further increase of electron density outside the nitrogen atom and a further decrease of electron density outside the pseudo pi-hole region, resulting in a stronger pseudo pi-hole interaction.	Nitrogen	178-186	neutrophil cytosolic factor 4	Homo sapiens	105-108
25430618-3	2015	In this multiple catalytic system, Yb(OTf)3 catalyzed the insertion of isonitriles to the N-H bond of amines, AgOTf catalyzed the 5-exo-dig cyclization of the resulting amidine nitrogen to the tethered triple bond, and KOTf promoted the salt metathesis, thus providing at the same time the counterion to the imidazolium.	Nitrogen	177-185	POU class 5 homeobox 1	Homo sapiens	38-43
8720802-2	1996	A series of new N-substituted derivatives of 3-[4-(2-methoxyphenyl)-1-piperazinyl]-2-phenylpropanamide, 6-10, were synthesized and their 5-HT1A, 5-HT2A, and alpha 1 receptor affinities were determined.	Nitrogen	16-17	5-hydroxytryptamine receptor 1A	Rattus norvegicus	137-143
27431089-3	2016	Compared with previously reported pH probes, CPH bearing the benzyl group at the nitrogen position of the indolium group and the phenol, which is used as the acceptor for proton, could respond to pH changes immediately through both the ratiometric fluorescence signal readout and naked-eye colorimetric observation.	Nitrogen	81-89	carboxypeptidase E	Homo sapiens	45-48
8720802-2	1996	A series of new N-substituted derivatives of 3-[4-(2-methoxyphenyl)-1-piperazinyl]-2-phenylpropanamide, 6-10, were synthesized and their 5-HT1A, 5-HT2A, and alpha 1 receptor affinities were determined.	Nitrogen	16-17	5-hydroxytryptamine receptor 2A	Rattus norvegicus	145-151
8554050-3	1996	The Con1 glycoprotein is encoded in exon 3 of a PRB2 allele (PRB2L CON1+) with a potential N-linked glycosylation site.	Nitrogen	69-70	proline rich protein BstNI subfamily 2	Homo sapiens	4-21
27451899-8	2016	The nap1 mutant (and KO mutants of other components of the SCAR/WAVE and ARP2/3 complexes) is more susceptible to nitrogen starvation and is less salt tolerant, indicating defective autophagy.	Nitrogen	114-122	transcription activator	Arabidopsis thaliana	4-8
8554050-3	1996	The Con1 glycoprotein is encoded in exon 3 of a PRB2 allele (PRB2L CON1+) with a potential N-linked glycosylation site.	Nitrogen	69-70	proline rich protein BstNI subfamily 2	Homo sapiens	48-52
27216556-4	2016	Faecal N appeared not to be influenced by N intake and exceeded 11 g/kg dry matter intake (DMI) only in 7% of the data sets available.	Nitrogen	7-8	DMI	Bos taurus	91-94
8548878-3	1996	The results indicated an enantioselective excretion of the parent and N-dechloroethylated metabolites: the urinary recovery of (R)-IFF was significantly greater than that of (S)-IFF (1.73 +/- 0.45 vs 1.43 +/- 0.41 mmol, P &lt; 0.0001); the excretion of (S)-2-DCE-IFF (0.75 +/- 0.53 mmol) was greater than that of (R)-2-DCE-IFF (0.42 +/- 0.22 mmol, P = 0.071) while the excretion of (R)-3-DCE-IFF (1.64 +/- 0.76 mmol) was greater than that of (S)-3-DCE-IFF (0.77 +/- 0.59 mmol, P = 0.012).	Nitrogen	70-71	interferon beta 1	Homo sapiens	131-134
27118799-7	2016	These findings suggested that Zip1 plays roles in zinc uptake in C. neoformans We also constructed a Zip1-FLAG fusion protein and found, by immunofluorescence, not only that the protein was localized to the periphery implying it is a membrane transporter, but also that the protein was N-glycosylated.	Nitrogen	286-287	solute carrier family 39 (zinc transporter), member 1	Mus musculus	30-34
27118799-7	2016	These findings suggested that Zip1 plays roles in zinc uptake in C. neoformans We also constructed a Zip1-FLAG fusion protein and found, by immunofluorescence, not only that the protein was localized to the periphery implying it is a membrane transporter, but also that the protein was N-glycosylated.	Nitrogen	286-287	solute carrier family 39 (zinc transporter), member 1	Mus musculus	101-105
8548878-3	1996	The results indicated an enantioselective excretion of the parent and N-dechloroethylated metabolites: the urinary recovery of (R)-IFF was significantly greater than that of (S)-IFF (1.73 +/- 0.45 vs 1.43 +/- 0.41 mmol, P &lt; 0.0001); the excretion of (S)-2-DCE-IFF (0.75 +/- 0.53 mmol) was greater than that of (R)-2-DCE-IFF (0.42 +/- 0.22 mmol, P = 0.071) while the excretion of (R)-3-DCE-IFF (1.64 +/- 0.76 mmol) was greater than that of (S)-3-DCE-IFF (0.77 +/- 0.59 mmol, P = 0.012).	Nitrogen	70-71	interferon beta 1	Homo sapiens	178-181
8548878-3	1996	The results indicated an enantioselective excretion of the parent and N-dechloroethylated metabolites: the urinary recovery of (R)-IFF was significantly greater than that of (S)-IFF (1.73 +/- 0.45 vs 1.43 +/- 0.41 mmol, P &lt; 0.0001); the excretion of (S)-2-DCE-IFF (0.75 +/- 0.53 mmol) was greater than that of (R)-2-DCE-IFF (0.42 +/- 0.22 mmol, P = 0.071) while the excretion of (R)-3-DCE-IFF (1.64 +/- 0.76 mmol) was greater than that of (S)-3-DCE-IFF (0.77 +/- 0.59 mmol, P = 0.012).	Nitrogen	70-71	interferon beta 1	Homo sapiens	178-181
8548878-3	1996	The results indicated an enantioselective excretion of the parent and N-dechloroethylated metabolites: the urinary recovery of (R)-IFF was significantly greater than that of (S)-IFF (1.73 +/- 0.45 vs 1.43 +/- 0.41 mmol, P &lt; 0.0001); the excretion of (S)-2-DCE-IFF (0.75 +/- 0.53 mmol) was greater than that of (R)-2-DCE-IFF (0.42 +/- 0.22 mmol, P = 0.071) while the excretion of (R)-3-DCE-IFF (1.64 +/- 0.76 mmol) was greater than that of (S)-3-DCE-IFF (0.77 +/- 0.59 mmol, P = 0.012).	Nitrogen	70-71	interferon beta 1	Homo sapiens	178-181
27347815-0	2016	Interactions between SF4 and Fluoride: A Crystallographic Study of Solvolysis Products of SF4 Nitrogen-Base Adducts by HF.	Nitrogen	94-102	SURP and G-patch domain containing 1	Homo sapiens	21-24
27347815-0	2016	Interactions between SF4 and Fluoride: A Crystallographic Study of Solvolysis Products of SF4 Nitrogen-Base Adducts by HF.	Nitrogen	94-102	SURP and G-patch domain containing 1	Homo sapiens	90-93
27347815-1	2016	Adducts between SF4 and a nitrogen base are easily solvolyzed by HF, yielding the protonated nitrogen base and fluoride.	Nitrogen	26-34	SURP and G-patch domain containing 1	Homo sapiens	16-19
8548878-3	1996	The results indicated an enantioselective excretion of the parent and N-dechloroethylated metabolites: the urinary recovery of (R)-IFF was significantly greater than that of (S)-IFF (1.73 +/- 0.45 vs 1.43 +/- 0.41 mmol, P &lt; 0.0001); the excretion of (S)-2-DCE-IFF (0.75 +/- 0.53 mmol) was greater than that of (R)-2-DCE-IFF (0.42 +/- 0.22 mmol, P = 0.071) while the excretion of (R)-3-DCE-IFF (1.64 +/- 0.76 mmol) was greater than that of (S)-3-DCE-IFF (0.77 +/- 0.59 mmol, P = 0.012).	Nitrogen	70-71	interferon beta 1	Homo sapiens	178-181
27285083-5	2016	In case of 4H(+), a rapid migration (in the NMR time scale) of the NH proton between two nitrogen atoms along the N-H   N hydrogen bond was registered at room temperature and frozen below -30  C with the proton fixed on the NMe2 group.	Nitrogen	89-97	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	224-228
8548878-3	1996	The results indicated an enantioselective excretion of the parent and N-dechloroethylated metabolites: the urinary recovery of (R)-IFF was significantly greater than that of (S)-IFF (1.73 +/- 0.45 vs 1.43 +/- 0.41 mmol, P &lt; 0.0001); the excretion of (S)-2-DCE-IFF (0.75 +/- 0.53 mmol) was greater than that of (R)-2-DCE-IFF (0.42 +/- 0.22 mmol, P = 0.071) while the excretion of (R)-3-DCE-IFF (1.64 +/- 0.76 mmol) was greater than that of (S)-3-DCE-IFF (0.77 +/- 0.59 mmol, P = 0.012).	Nitrogen	70-71	interferon beta 1	Homo sapiens	178-181
8834812-3	1996	Here we show that VIP36 is N-glycosylated and expressed in organs abundant in epithelial cells as well as in non-epithelial organs.	Nitrogen	27-28	lectin, mannose binding 2	Canis lupus familiaris	18-23
27064685-2	2016	We have modeled the N-hydroxylation of (R)-mexiletine in CYP1A2 with hybrid quantum mechanics/molecular mechanics (QM/MM) methods, providing a more detailed and realistic model.	Nitrogen	20-21	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	57-63
26957519-4	2016	Growth on D-serine as the sole source of nitrogen was retained in the  dsdA mutant and was abolished completely in the  dadA and  dadA- dsdA mutants.	Nitrogen	41-49	D-amino acid dehydrogenase small subunit	Pseudomonas aeruginosa PAO1	120-124
8971922-6	1996	Our results show the presence of N-terminally processed CGA in PC12 cells.	Nitrogen	33-34	chromogranin A	Rattus norvegicus	56-59
26957519-4	2016	Growth on D-serine as the sole source of nitrogen was retained in the  dsdA mutant and was abolished completely in the  dadA and  dadA- dsdA mutants.	Nitrogen	41-49	D-amino acid dehydrogenase small subunit	Pseudomonas aeruginosa PAO1	130-134
27498891-0	2016	Delayed N2 response in Go condition in a visual Go/Nogo ERP study in children who stutter.	Nitrogen	8-10	reticulon 4	Homo sapiens	51-55
8639257-3	1996	In patients with acute rejection, the serum HGF level was markedly increased (over 1 ng/ml), and its elevation was accompanied by an increase in serum creatinine and blood urea nitrogen (BUN).	Nitrogen	177-185	hepatocyte growth factor	Homo sapiens	44-47
27148755-1	2016	N-Acetylation of the tetrahydroquinoline (THQ) core of a series of mu-opioid receptor (MOR) agonist/delta-opioid receptor (DOR) antagonist ligands increases DOR affinity, resulting in ligands with balanced MOR and DOR affinities.	Nitrogen	0-1	opioid receptor mu 1	Homo sapiens	67-85
8585318-4	1995	The predicted Pmt3p contains 753 amino acids, four potential N-glycosylation sites and it is significantly homologous to Pmt1p, Pmt2p and Pmt4p.	Nitrogen	61-62	dolichyl-phosphate-mannose-protein mannosyltransferase PMT3	Saccharomyces cerevisiae S288C	14-19
27148755-1	2016	N-Acetylation of the tetrahydroquinoline (THQ) core of a series of mu-opioid receptor (MOR) agonist/delta-opioid receptor (DOR) antagonist ligands increases DOR affinity, resulting in ligands with balanced MOR and DOR affinities.	Nitrogen	0-1	opioid receptor mu 1	Homo sapiens	87-90
27148755-1	2016	N-Acetylation of the tetrahydroquinoline (THQ) core of a series of mu-opioid receptor (MOR) agonist/delta-opioid receptor (DOR) antagonist ligands increases DOR affinity, resulting in ligands with balanced MOR and DOR affinities.	Nitrogen	0-1	opioid receptor mu 1	Homo sapiens	206-209
7559653-0	1995	The role of N-glycosylation for functional expression of the human platelet-activating factor receptor.	Nitrogen	12-13	platelet activating factor receptor	Homo sapiens	67-102
27227887-5	2016	These phenotypes were rescued by TORC1 inhibition using pharmacological or genetic means, and the loss of Lam2, Gtr1, Gtr2, Npr2 or Npr3 disinhibited TORC1 activity under nitrogen depletion, as measured by Rps6 phosphorylation.	Nitrogen	171-179	Ysp2p	Saccharomyces cerevisiae S288C	106-110
27227887-5	2016	These phenotypes were rescued by TORC1 inhibition using pharmacological or genetic means, and the loss of Lam2, Gtr1, Gtr2, Npr2 or Npr3 disinhibited TORC1 activity under nitrogen depletion, as measured by Rps6 phosphorylation.	Nitrogen	171-179	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	112-116
26774085-0	2016	A fluorescence resonance energy transfer (FRET) based "Turn-On" nanofluorescence sensor using a nitrogen-doped carbon dot-hexagonal cobalt oxyhydroxide nanosheet architecture and application to alpha-glucosidase inhibitor screening.	Nitrogen	96-104	sucrase-isomaltase	Homo sapiens	194-211
27133130-6	2016	These findings describe a competitive and partially redundant relationship between transaminases and GLUD, and they reveal how coupling of glutamate-derived carbon and nitrogen metabolism can be regulated to support cell proliferation.	Nitrogen	168-176	glutamate dehydrogenase 1	Homo sapiens	101-105
26911932-0	2016	A human FSHB transgene encoding the double N-glycosylation mutant (Asn(7Delta) Asn(24Delta)) FSHbeta subunit fails to rescue Fshb null mice.	Nitrogen	43-44	follicle stimulating hormone subunit beta	Homo sapiens	8-12
26911932-0	2016	A human FSHB transgene encoding the double N-glycosylation mutant (Asn(7Delta) Asn(24Delta)) FSHbeta subunit fails to rescue Fshb null mice.	Nitrogen	43-44	follicle stimulating hormone subunit beta	Homo sapiens	93-100
26911932-6	2016	We demonstrate that the human FSHbeta(Asn7Delta 24Delta) double N-glycosylation site mutant subunit, unlike human FSHbeta WT subunit, inefficiently combines with the mouse alpha-subunit in pituitaries of Fshb null mice.	Nitrogen	64-65	follicle stimulating hormone subunit beta	Homo sapiens	30-37
27127019-1	2016	In aviation and diving, fast decrease in ambient pressure, such as during accidental loss of cabin pressure or when a diver decompresses too fast to sea level, may cause nitrogen (N2) bubble formation in blood and tissue resulting in decompression sickness (DCS).	Nitrogen	170-178	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	149-152
27127019-1	2016	In aviation and diving, fast decrease in ambient pressure, such as during accidental loss of cabin pressure or when a diver decompresses too fast to sea level, may cause nitrogen (N2) bubble formation in blood and tissue resulting in decompression sickness (DCS).	Nitrogen	180-182	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	149-152
27123103-0	2016	N-glycosylation of R-spondin1 at Asn137 negatively regulates its secretion and Wnt/beta-catenin signaling-enhancing activity.	Nitrogen	0-1	catenin beta 1	Homo sapiens	83-95
27123103-3	2016	The present study identified that RSPO1 was N-glycosylated at Asn137, and that N-glycosylation of RSPO1 negatively influenced its secretion and enhancing effect on Wnt/beta-catenin signaling.	Nitrogen	44-45	catenin beta 1	Homo sapiens	168-180
27123103-3	2016	The present study identified that RSPO1 was N-glycosylated at Asn137, and that N-glycosylation of RSPO1 negatively influenced its secretion and enhancing effect on Wnt/beta-catenin signaling.	Nitrogen	79-80	catenin beta 1	Homo sapiens	168-180
27123103-10	2016	These results suggest that N-glycosylation of RSPO1 has a negative influence on its secretion and Wnt/beta-catenin signaling-enhancing effect.	Nitrogen	27-28	catenin beta 1	Homo sapiens	102-114
26805515-5	2016	We show that incorporating an N-methyl moiety controls the conformation of the macrocycle, which dramatically impacts cytotoxicity and binding affinity for Hsp90.	Nitrogen	30-31	heat shock protein 90 alpha family class A member 1	Homo sapiens	156-161
26844930-5	2016	The most potent inhibitor 2-(benzyloxy)-6-(4-chloro-3,5-dimethylphenoxy)nicotinic acid (1 r: Ki =2.90 mum) likely binds in the p2 pocket of Mcl-1 and engages R263 in a salt bridge through its carboxylic acid, as supported by 2D (1) H-(15) N HSQC NMR data.	Nitrogen	239-240	MCL1 apoptosis regulator, BCL2 family member	Homo sapiens	140-145
26725056-9	2016	Here we report (1)H, (15)N, (13)CO, (13)Calpha and (13)Cbeta NMR chemical shift assignments of the emerin fragment from residue 67 to residue 170, which is sufficient for nuclear localization and involved in lamin A binding.	Nitrogen	25-26	emerin	Homo sapiens	99-105
26403526-1	2016	Facilitative UT-B urea transporters play an important role in the urea nitrogen salvaging process that occurs in the gastrointestinal tract of mammals, particularly ruminants.	Nitrogen	71-79	solute carrier family 14 member 1	Bos taurus	13-17
26785728-7	2016	By multiplexed capillary gel electrophoresis coupled to laser induced fluorescence detection (xCGE-LIF) we could show that PMM2-iPSC-C3 exhibit the common hPSC N-glycosylation pattern with high-mannose-type N-glycans as the predominant species.	Nitrogen	160-161	LIF interleukin 6 family cytokine	Homo sapiens	99-102
26785728-9	2016	In addition, quantitative assessment of N-glycosylation by xCGE-LIF showed an up to 40% reduction of high-mannose-type N-glycans in PMM2-iPSC-C3, which was in concordance to the observed reduction of the Glc3Man9GlcNAc2 lipid-linked oligosaccharide compared with control hPSCs.	Nitrogen	40-41	LIF interleukin 6 family cytokine	Homo sapiens	64-67
26669329-1	2016	Although there is evidence for an important role of UGT2B10 in the N-glucuronidation of drugs and other xenobiotics, the inhibitor selectivity of this enzyme is poorly understood.	Nitrogen	67-68	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	52-59
26856397-5	2016	Olanzapine N-demethylation and N-oxygenation were found to be catalyzed by CYP1A2 and CYP2D6 and by CYP2D6 and FMO3, respectively, in experiments using liver microsomes and recombinant enzymes.	Nitrogen	11-12	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	75-81
26727398-8	2016	The NMR shift of N9 nitrogen of OG was particularly studied because the atom is involved in an N-glycosidic bond that is cleaved with hOGG1.	Nitrogen	20-28	8-oxoguanine DNA glycosylase	Homo sapiens	134-139
26727398-12	2016	We therefore assume that the pyramidal geometry of N9 nitrogen that could occur for damaged DNA within hOGG1 catalytic site might be detectable with (15)N NMR spectroscopy.	Nitrogen	54-62	8-oxoguanine DNA glycosylase	Homo sapiens	103-108
26611529-1	2016	NGLY1/Ngly1 is a cytosolic peptide:N-glycanase, i.e. de-N-glycosylating enzyme acting on N-glycoproteins in mammals, generating free, unconjugated N-glycans and deglycosylated peptides in which the N-glycosylated asparagine residues are converted to aspartates.	Nitrogen	0-1	N-glycanase 1	Homo sapiens	6-11
26833332-9	2016	Abnormal N- and mucin type O-glycosylation was found on serum proteins, and reduced metabolic labeling of sialic acids was found in fibroblasts, which was restored after complementation with wild-type CCDC115.	Nitrogen	9-10	coiled-coil domain containing 115	Homo sapiens	201-208
26751503-6	2016	It also exhibits a record-high volumetric CO2 uptake of 167 v/v at 1 bar and 298 K. Ideal adsorbed solution theory calculations showed a CO2/N2 (molar ratio 15:85) selectivity of 93 and CO2/H2 (molar ratio 30:70) selectivity above 1700.	Nitrogen	141-143	complement C2	Homo sapiens	186-192
27250875-3	2016	By deploying a genetic screen for suppressors of cell death triggered by virus-induced gene silencing of BAK1/SERK4 on Arabidopsis knockout collections, we identified STT3a, a protein involved in N-glycosylation modification, as an important regulator of bak1/serk4 cell death.	Nitrogen	196-197	somatic embryogenesis receptor-like kinase 4	Arabidopsis thaliana	260-265
27250875-7	2016	Therefore, N-glycosylation and specific ERQC components are essential to activate bak1/serk4 cell death, and CRK4 is likely to be among client proteins of protein glycosylation involved in BAK1/SERK4-regulated cell death.	Nitrogen	11-12	somatic embryogenesis receptor-like kinase 4	Arabidopsis thaliana	87-92
27250875-7	2016	Therefore, N-glycosylation and specific ERQC components are essential to activate bak1/serk4 cell death, and CRK4 is likely to be among client proteins of protein glycosylation involved in BAK1/SERK4-regulated cell death.	Nitrogen	11-12	somatic embryogenesis receptor-like kinase 4	Arabidopsis thaliana	194-199
26659026-2	2016	NBS participates in multiple tasks, such as bromonium ion formation, oxidation of bromohydrin and providing a nucleophilic nitrogen source.	Nitrogen	123-131	nibrin	Homo sapiens	0-3
26777976-2	2016	A novel highly sensitive photoelectrochemical (PEC) aptsensor was developed for the detection of TXNDC5 by using the nanohybrids (TiO2 NRs/NCQDs) of nitrogen-doped carbon quantum dots (NCQDs) and TiO2 nanorods as the photo-to-electron conversion medium.	Nitrogen	149-157	thioredoxin domain containing 5	Homo sapiens	97-103
26955355-7	2015	The two approaches produced consistent results and showed that the anti-hepcidin activity strongly decreases with molecular weight below 7 kD, with high N-acetylation and after 2-O and 6-O desulfation.	Nitrogen	153-154	hepcidin antimicrobial peptide	Homo sapiens	72-80
25535363-8	2015	Intriguingly, genetic and molecular analysis indicated that N-glycosylation of CKX1 was not affected by the lack of ROCK1-mediated supply of UDP-GlcNAc.	Nitrogen	60-61	cytokinin oxidase/dehydrogenase 1	Arabidopsis thaliana	79-83
25470979-2	2015	DDR1 and DDR2 transfected in HEK293 cells were expressed mainly as 120 and 130 kDa forms, respectively, as they are sufficiently N-glycosylated.	Nitrogen	129-130	discoidin domain receptor tyrosine kinase 1	Homo sapiens	0-4
26457198-8	2015	Dal81, a general positive regulator of genes involved in nitrogen utilization related to the metabolisms of GABA, leucine, and allantoin, plays a central role in this coordinated regulation.	Nitrogen	57-65	Dal81p	Saccharomyces cerevisiae S288C	0-5
26252500-5	2015	THB1 and THB2 are regulated by the nitrogen source and respond differentially to NO and the nitrate/ammonium balance.	Nitrogen	35-43	uncharacterized protein	Chlamydomonas reinhardtii	9-13
25354954-4	2014	We demonstrate that SPPL3 alters the pattern of cellular N-glycosylation by triggering the proteolytic release of active site-containing ectodomains of glycosidases and glycosyltransferases such as N-acetylglucosaminyltransferase V, beta-1,3 N-acetylglucosaminyltransferase 1 and beta-1,4 galactosyltransferase 1.	Nitrogen	57-58	beta-1,4-galactosyltransferase 1	Homo sapiens	280-312
25278359-5	2014	Whereas the Cu NPs acted as the catalyst for the reduction, CeO2 facilitated the incorporation of nitrogen from the pyridine source into the ACF/CNF surface.	Nitrogen	98-106	ACF	Homo sapiens	141-144
25502225-1	2014	Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation.	Nitrogen	128-136	glutaminase	Homo sapiens	28-39
25502225-1	2014	Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation.	Nitrogen	128-136	glutaminase	Homo sapiens	41-44
28324312-3	2014	During protein assimilation in our body surplus nitrogen is made, this open nitrogen is altered into urea and expelled out of the body by kidneys, in this cycle OTC helps in the conversion of free toxic nitrogen into urea.	Nitrogen	48-56	ornithine transcarbamylase	Homo sapiens	161-164
28324312-3	2014	During protein assimilation in our body surplus nitrogen is made, this open nitrogen is altered into urea and expelled out of the body by kidneys, in this cycle OTC helps in the conversion of free toxic nitrogen into urea.	Nitrogen	76-84	ornithine transcarbamylase	Homo sapiens	161-164
28324312-3	2014	During protein assimilation in our body surplus nitrogen is made, this open nitrogen is altered into urea and expelled out of the body by kidneys, in this cycle OTC helps in the conversion of free toxic nitrogen into urea.	Nitrogen	76-84	ornithine transcarbamylase	Homo sapiens	161-164
25336660-0	2014	N-glycosylation regulates ADAM8 processing and activation.	Nitrogen	0-1	ADAM metallopeptidase domain 8	Homo sapiens	26-31
25336660-4	2014	Here, we report that in estrogen receptor (ER)alpha-negative, but not -positive, breast cancer cells ADAM8 contains N-glycosylation, which is required for its correct processing and activation.	Nitrogen	116-117	ADAM metallopeptidase domain 8	Homo sapiens	101-106
25336660-6	2014	Site-directed mutagenesis confirmed four N-glycosylazhytion sites (Asn-67, Asn-91, Asn-436, and Asn-612) in human ADAM8.	Nitrogen	41-42	ADAM metallopeptidase domain 8	Homo sapiens	114-119
25336660-11	2014	Thus, N-glycosylation is essential for processing, localization, stability, and activity of ADAM8.	Nitrogen	6-7	ADAM metallopeptidase domain 8	Homo sapiens	92-97
25375040-4	2014	The polymeric chain in 3 could be disrupted by reaction with triphenylphosphine, and the resulting complex, [Ag(oL)(PPh3)](OTf), 4, possessed a monometallic cation where the ligand was bound to silver in a chelating kappa(2)P,N- coordination mode.	Nitrogen	226-227	protein phosphatase 4 catalytic subunit	Homo sapiens	116-120
25262405-1	2014	The aim of the paper was to evaluate 23 catchment factors that determine total phosphorus and total nitrogen load to the Baltic Sea.	Nitrogen	100-108	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	128-131
25250725-1	2014	This work details the evaluation of a number of N-alkylated deoxynojirimycin derivatives on their merits as dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.	Nitrogen	48-49	UDP-glucose ceramide glucosyltransferase	Homo sapiens	113-138
25250725-1	2014	This work details the evaluation of a number of N-alkylated deoxynojirimycin derivatives on their merits as dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.	Nitrogen	48-49	glucosylceramidase beta	Homo sapiens	147-165
25281559-0	2014	Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of alpha-mannosidase under nitrogen starvation conditions.	Nitrogen	108-116	serine/threonine protein kinase HRR25	Saccharomyces cerevisiae S288C	0-5
25281559-0	2014	Hrr25 phosphorylates the autophagic receptor Atg34 to promote vacuolar transport of alpha-mannosidase under nitrogen starvation conditions.	Nitrogen	108-116	Atg34p	Saccharomyces cerevisiae S288C	45-50
25281559-1	2014	In Saccharomyces cerevisiae, under nitrogen-starvation conditions, the alpha-mannosidase Ams1 is recognized by the autophagic receptor Atg34 and transported into the vacuole, where it functions as an active enzyme.	Nitrogen	35-43	Atg34p	Saccharomyces cerevisiae S288C	135-140
25234271-1	2014	MP2/aug-cc-pVTZ calculations were performed on triel trifluorides, ZF3 (Z=B, Al, Ga, In, Tl), and their complexes with N2 and HCN species, which are acting as Lewis bases.	Nitrogen	119-121	tryptase pseudogene 1	Homo sapiens	0-3
25095973-0	2014	Modulation of aquaporin 2 expression in the kidney of young goats by changes in nitrogen intake.	Nitrogen	80-88	aquaporin-2	Capra hircus	14-25
25237315-7	2014	In the case of plants, it is well known that another type of PNGase, the acidic PNGase (aPNGase) is involved in the production of plant complex type FNGs in an acidic organelle, suggesting the de-N-glycosylation mechanism in plants is different from that in animal cells.	Nitrogen	62-63	N-glycanase 1	Homo sapiens	80-86
25129170-7	2014	Taken together, the results indicate that deletion of the positively charged nitrogen in mu opioid analgesics reduces MOR binding affinity by 2-3 orders of magnitude and may have pronounced effects on the intrinsic efficacy and on the opioid receptor selectivity profile.	Nitrogen	77-85	opioid receptor mu 1	Homo sapiens	118-121
24970053-9	2014	Hence, various concentrations of tunicamycin were used to treat the cells in order to study its influence on CD147 N-glycosylation and MMP-2 expression.	Nitrogen	115-116	basigin (Ok blood group)	Homo sapiens	109-114
24970053-10	2014	In conclusion, we found that beta3GnT8 regulated the level of N-glycans on CD147 and that N-glycosylation of CD147 has an important effect on MMP-2 expression.	Nitrogen	62-63	basigin (Ok blood group)	Homo sapiens	75-80
25092115-1	2014	We report on a one-step method for preparing nitrogen doped (N-doped) meso-/microporous hybrid carbon material (NCF) via the heat treatment of used cigarette filters under a nitrogen-containing atmosphere.	Nitrogen	45-53	neutrophil cytosolic factor 4	Homo sapiens	112-115
25092115-1	2014	We report on a one-step method for preparing nitrogen doped (N-doped) meso-/microporous hybrid carbon material (NCF) via the heat treatment of used cigarette filters under a nitrogen-containing atmosphere.	Nitrogen	174-182	neutrophil cytosolic factor 4	Homo sapiens	112-115
25144769-12	2014	With respect to high fat diet, changes in the mARC proteins occur that result in increased N-reductive activity.	Nitrogen	91-92	activity regulated cytoskeletal-associated protein	Mus musculus	46-50
24946216-1	2014	Thanks to a preliminary in vitro screening of several CCl3-substituted-nitrogen containing heterocycles belonging to our chemical library, the 2-trichloromethylquinoxaline scaffold appeared to be of potential interest for developing new antiplasmodial agents.	Nitrogen	71-79	C-C motif chemokine ligand 3	Homo sapiens	54-58
25120578-3	2014	We previously reported that N-glycosylation of recombinant gp120 varied, depending on the producer cells, and the glycosylation variability affected gp120 recognition by serum antibodies from persons infected with HIV-1 subtype B.	Nitrogen	28-29	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	59-64
24930989-6	2014	This is in accordance with the finding that protein expression of NifH is highly reduced in the absence of MM1708 under nitrogen-limited conditions.	Nitrogen	120-128	nitrogenase iron protein	Methanosarcina mazei Go1	66-70
25010511-2	2014	The addition of hydrogen peroxide (30% aq) as a co-oxidant in the system is crucial for the dehydrogenative aminohalogenation under molecular oxygen (1 atm), and in such a case, the C-N bond coupling/electrophilic bromination reaction cascade is proposed.	Nitrogen	184-185	ATM serine/threonine kinase	Homo sapiens	152-155
26739646-3	2016	Moreover, Golgi-to-endosome trafficking was shown to be required for nuclear translocation of Gln3 upon a shift from rich medium to the poor nitrogen source proline, but not upon rapamycin treatment.	Nitrogen	141-149	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	94-98
26691649-4	2016	It was determined that this threshold was 4.18% NR4(+) bonded nitrogen with a surface potential of + 120.4 mV.	Nitrogen	62-70	interleukin 13 receptor subunit alpha 1	Homo sapiens	48-51
26551063-1	2016	The copper-gonadotropin-releasing hormone molecule (Cu-GnRH) is a GnRH analog, which preserves its amino acid sequence, but which contains a Cu(2+) ion stably bound to the nitrogen atoms including that of the imidazole ring of Histidine(2).	Nitrogen	172-180	gonadotropin releasing hormone 1	Rattus norvegicus	55-59
27656047-1	2016	Reactive oxygen species (ROS) and nitrogen species have an indispensable role in regulating cell signalling pathways, including transcriptional control via hypoxia inducible factor-1alpha (HIF-1alpha).	Nitrogen	34-42	hypoxia inducible factor 1, alpha subunit	Mus musculus	156-187
27656047-1	2016	Reactive oxygen species (ROS) and nitrogen species have an indispensable role in regulating cell signalling pathways, including transcriptional control via hypoxia inducible factor-1alpha (HIF-1alpha).	Nitrogen	34-42	hypoxia inducible factor 1, alpha subunit	Mus musculus	189-199
27811481-10	2016	CONCLUSIONS: Treatment of 3D skin models with the plasma MEF nozzle using air or nitrogen is reported.	Nitrogen	81-89	E74 like ETS transcription factor 4	Homo sapiens	57-60
27508376-4	2016	The total nitrogen (TN) removal rate was 94.4% in our newly developed E-BF, but only 74.7% in the control BF.	Nitrogen	10-18	EBF transcription factor 1	Homo sapiens	70-74
24938410-6	2014	The co-ordination of Hg(2+) and CH3Hg(+) to the nitrogen atom of the MPY ring yields characteristic changes in the vibrational SERS spectra of the organic chemoreceptor that can be qualitatively and quantitatively correlated to the presence of the two different mercury forms.	Nitrogen	48-56	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	127-131
7559653-4	1995	Because bacterial binding is in part carbohydrate dependent, and the human platelet-activating factor (PAF) receptor bears a single N-linked glycosylation sequence in the second extracellular loop, we undertook studies to determine the role of this epitope in PAF receptor function.	Nitrogen	132-133	platelet activating factor receptor	Homo sapiens	75-116
25004282-8	2014	The chemically generated [Ru2(dpb)4(CO)](+) complex undergoes several electron transfer processes in CH2Cl2 containing 0.1 M TBAClO4 under a CO atmosphere, and the same reactions were seen for a chemically synthesized sample of Ru2(dpf)4(CO) in CH2Cl2, 0.1 M TBAClO4 under a N2 atmosphere, where dpf = N,N"-diphenylformamidinate anion.	Nitrogen	275-277	doublecortin domain containing 2	Homo sapiens	26-29
26732492-3	2015	However, it has recently become clear that the protein is N-glycosylated within the endoplasmic reticulum of plant cells-a eukaryotic post-translational modification that is not present in native CTB.	Nitrogen	58-59	chitobiase	Homo sapiens	196-199
26732492-5	2015	Based on data from our recent studies, I discuss the unique features of N-glycosylated CTB produced in plants for the development of novel vaccines.	Nitrogen	72-73	chitobiase	Homo sapiens	87-90
7562931-4	1995	These compounds inhibit HNE by forming both a covalent bond between the ketone carbonyl carbon atom and the hydroxyl group of Ser-195 and a hydrogen bond between the benzoxazole nitrogen atom and His-57.	Nitrogen	178-186	elastase, neutrophil expressed	Homo sapiens	24-27
26633377-11	2015	The complex models by docking simulation suggested that the intermolecular hydrogen bond via the nitrogen of thiourea and the contacts via thione were equally important for interacting with tyrosinase.	Nitrogen	97-105	tyrosinase	Mus musculus	190-200
24780116-9	2014	However, administration of N-nitrosomethylurea and/or Helicobacter felis infection promoted methylation of p19(arf) CpG islands in the gastrointestinal tracts, but did not promote p16(ink4a) methylation.	Nitrogen	27-28	cyclin dependent kinase inhibitor 2D	Mus musculus	107-110
24947828-6	2014	The functions of the four validated genes, GCN1, MDS3, ARG81 and BIO3, relate to key roles in nitrogen metabolism and signaling, helping to maintain fermentation performance.	Nitrogen	94-102	Mds3p	Saccharomyces cerevisiae S288C	49-53
12506411-3	1995	Significant binding of CsA was detected with 35 synthetic N alpha-acetylated octapeptides possessing the N-terminal amino acids corresponding to the residues in positions 24-26, 42-44, 69-73, 75, 76, 89-91, 102, 116, 124-131, 144-151 and 152 in human CyP A, respectively.	Nitrogen	58-59	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	Homo sapiens	23-26
24813619-4	2014	Deprotonation of this complex with NaH resulted in the formation of the dinuclear complex [{Pd(dmba)}2(mu-L)] (4) in which a shift of the Pd(II) centers from the NPy sites to the N,O donor sites of the zwitterion core has occurred, resulting in a N2O2 tetradentate behavior of ligand L. Reaction of 4 with HCl regenerates 3 quantitatively.	Nitrogen	35-36	neuropeptide Y	Homo sapiens	162-165
24644271-2	2014	Expression of NCR-sensitive genes is mediated by two transcription activators, Gln3 and Gat1, in response to provision of a poorly used nitrogen source or following treatment with the TORC1 inhibitor, rapamycin.	Nitrogen	136-144	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	79-83
24644271-4	2014	Here, we show that Vps components are required for Gln3 localization and function in response to rapamycin treatment when cells are grown in defined yeast nitrogen base but not in complex yeast peptone dextrose medium.	Nitrogen	155-163	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	51-55
26376583-3	2015	If the vapor of the ionic liquid [EMImH(+) ][AcO(-) ] is trapped in solid argon or nitrogen at 9 K, only acetic acid (AcOH) and the carbene, but no ionic species, are found by IR spectroscopy.	Nitrogen	83-91	kallikrein related peptidase 15	Homo sapiens	45-48
26367528-0	2015	Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum.	Nitrogen	21-22	serpin family I member 1	Homo sapiens	66-77
26367528-8	2015	In summary, our results indicate how normal and variant-specific N-linked glycosylation events relate to intracellular folding, misfolding, degradation and polymerisation of neuroserpin.	Nitrogen	65-66	serpin family I member 1	Homo sapiens	174-185
7574684-0	1995	Extracellular domain of neurotrophin receptor trkB: disulfide structure, N-glycosylation sites, and ligand binding.	Nitrogen	73-74	neurotrophic receptor tyrosine kinase 2	Homo sapiens	46-50
24821292-6	2014	The highest occupied molecular orbital (HOMO) of CS shows leading carbonyl pi character with contributions from other heavy (non-H) atoms in the molecule, while the HOMO of 2-oxazolidinone (OX2) has leading nitrogen, carbon, and oxygen ppi characters.	Nitrogen	207-215	CD200 molecule	Homo sapiens	190-193
7574684-6	1995	Among 12 potential N-linked glycosylation sites proposed in the soluble domain of trkB, 10 sites are actually glycosylated.	Nitrogen	19-20	neurotrophic receptor tyrosine kinase 2	Homo sapiens	82-86
24671260-5	2014	Furthermore, several heteroboroxines containing nitrogen donor functionality (i.e. NH2, NMe2, CN or 4-pyridyl) included in the boronic acid residue were synthesized and characterized with the aim to prepare boroxine-based covalent frameworks (through intermolecular N B interactions) containing metal atoms in their structures.	Nitrogen	48-56	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	88-92
25199249-7	2014	RESULTS &amp; CONCLUSION: We obtained a delta och1 delta alg3 delta mnn1 strain that produces Man5 GlcNAc2 intermediate of human N-glycosylation.	Nitrogen	16-17	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	46-50
26837248-8	2015	RESULTS: (1) On PID 1, the levels of urea nitrogen and creatinine were (9.0 +- 3.2) mmol/L and (115 +- 24) micromol/L respectively, which were obviously higher than normal values (with the values of 2.9-8.2 mmol/L and 45-104 micromol/L respectively).	Nitrogen	42-50	phosphotyrosine interaction domain containing 1	Homo sapiens	16-21
26837248-10	2015	On PID 14, the level of urea nitrogen was (15.8 +- 3.3) mmol/L, which was obviously higher than the value of PID 1 (t =3 .29, P = 0.023).	Nitrogen	29-37	phosphotyrosine interaction domain containing 1	Homo sapiens	3-8
26584676-2	2015	Here, we use a diamond-nanocrystal-hosted nitrogen-vacancy centre attached to the apex of a silicon thermal tip as a local temperature sensor.	Nitrogen	42-50	TOR signaling pathway regulator	Homo sapiens	108-111
26584676-3	2015	We apply an electrical current to heat up the tip and rely on the nitrogen vacancy to monitor the thermal changes the tip experiences as it is brought into contact with surfaces of varying thermal conductivity.	Nitrogen	66-74	TOR signaling pathway regulator	Homo sapiens	118-121
25199249-11	2014	Our results demonstrate that delta och1 delta alg3 deltamnn1 triple mutant can be used as an initial strain to construct an yeast therapeutic glycoprotein-expression system by introducing various enzymes that are involved in human N-glycosylation pathway.	Nitrogen	231-232	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	35-39
24720891-3	2014	Our study here indicates that regulator of calcineurin 1 (RCAN1) can enhance N-glycosylation in ER, therefore elevates the activities of beta- and gamma-secretase and markedly increases Abeta production.	Nitrogen	61-62	regulator of calcineurin 1	Homo sapiens	30-56
26536264-9	2015	Multidimensional magic angle spinning (MAS) solid-state NMR of uniformly (13)C,(15)N-labeled protein was used to detect site-specific conformational changes in oxidized and reduced horse heart cyt-c bound to CL-containing lipid bilayers.	Nitrogen	56-57	cytochrome c, somatic	Equus caballus	193-198
7544576-0	1995	Structural and functional analysis of the canine histamine H2 receptor by site-directed mutagenesis: N-glycosylation is not vital for its action.	Nitrogen	101-102	histamine H2 receptor	Cricetulus griseus	49-70
24689752-2	2014	We examined the effects of changing the central bridging heteroatoms of the five-ring-fused thienoacene core identity from sulfur [DPP2(PTA)] to nitrogen [DPP2(NPTA)] in the small-molecule donor material.	Nitrogen	145-153	dipeptidyl peptidase 7	Homo sapiens	155-159
24689752-5	2014	Compared to DPP2(PTA) with no alkyl chain substituting on the central sulfur atom of the PTA unit, DPP2(NPTA) exhibits improved crystallinity and better miscibility with PC71BM probably because of a dodecyl chain on the central nitrogen atom of the NPTA unit.	Nitrogen	228-236	dipeptidyl peptidase 7	Homo sapiens	99-103
26617970-1	2015	A series of novel N-acyclic uracil analogs with linear, branched, aromatic, and cyclopropyl-alkynyl as well as heteroaryl moieties at C-5 were prepared using palladium catalyzed Sonogashira and Stille cross-coupling and evaluated against malignant tumor cell lines.	Nitrogen	18-19	complement C5	Homo sapiens	134-137
7544576-2	1995	The histamine H2 receptor is a member of the family of G-protein-coupled receptors, and has three extracellular potential sites for N-glycosylation (Asn-4, Asn-162 and Asn-168).	Nitrogen	132-133	histamine H2 receptor	Cricetulus griseus	4-25
7492680-5	1995	It was also inferred that the mature MOGP contained three potential N-linked glycosylation sites and 24 possible O-linked glycosylation sites, and had the unique seven-residue repeat sequence (21 repeats) within the predicted sequence in the C-terminal side.	Nitrogen	68-69	oviductal glycoprotein 1	Mus musculus	37-41
25220852-5	2015	The sequence also contained a putative N-glycosylation site and phosphorylation motifs for protein kinase A and protein kinase C. The oocyte swelling assay showed that AQP-x2 facilitated water permeability.	Nitrogen	39-40	aquaporin-Xl2	Xenopus laevis	168-174
24522408-2	2014	Unlike the generally accepted mechanism, involving relatively slow direct penetration of a proton into the cleft between the peri-NMe2 groups, it consists of the rapid addition of a proton to the out-inverted NMe2 group with the subsequent slower rotational transfer of the proton into the inter-nitrogen space to produce a stable chelated cation.	Nitrogen	296-304	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	130-134
24522408-2	2014	Unlike the generally accepted mechanism, involving relatively slow direct penetration of a proton into the cleft between the peri-NMe2 groups, it consists of the rapid addition of a proton to the out-inverted NMe2 group with the subsequent slower rotational transfer of the proton into the inter-nitrogen space to produce a stable chelated cation.	Nitrogen	296-304	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	209-213
26250108-3	2015	The cultivation of these isolates on nitrogen limited-medium revealed that GSY2 to GSY6, GSY10, FDY2, FDY12 and FDY14 accumulated lipid over 20% of dry biomass.	Nitrogen	37-45	glycogen (starch) synthase GSY2	Saccharomyces cerevisiae S288C	75-79
8535396-9	1995	These results suggest that a CYP2D isozyme(s) is the primary enzyme in alprenolol 4-hydroxylation and N-desisopropylation in a lower substrate concentration range, and that the involvement of some male-specific P450 isozyme(s) other than CYP2C11 or CYP3A2 may cause the sex difference in the 4-hydroxylation.	Nitrogen	102-103	cytochrome P450, family 3, subfamily a, polypeptide 2	Rattus norvegicus	249-255
26147653-5	2015	We contend that the ADEP"s N-acylphenylalanine moiety is not simply a stand-in for the ATPases" (I/L)GF motif; it likely has physicochemical properties that are better suited for ClpP binding.	Nitrogen	27-28	caseinolytic mitochondrial matrix peptidase proteolytic subunit	Homo sapiens	179-183
24699643-1	2014	The first step of nitrogen assimilation in higher plants, the energy-driven incorporation of ammonia into glutamate, is catalyzed by glutamine synthetase.	Nitrogen	18-26	LOC11405318	Medicago truncatula	133-153
24345054-1	2014	Gain-of-toxic-function mutations in Seipin (Asparagine 88 to Serine (N88S) and Serine 90 to Leucine (S90L) mutations, both of which disrupt the N-glycosylation) cause autosomal dominant motor neuron diseases.	Nitrogen	69-70	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	36-42
7648447-7	1995	The primary posttranslational modification of the mouse beta and gamma c subunits is N-linked glycosylation.	Nitrogen	85-86	interleukin 2 receptor, gamma chain	Mus musculus	65-72
24345054-3	2014	Here, we analyze the impact of disruption of N-glycosylation of Seipin on synaptic transmission by over-expressing mutant Seipin in cultured cortical neurons via lentiviral infection.	Nitrogen	45-46	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	64-70
24509848-5	2014	Here, we report that N-glycosylation at the Asn(211) residue plays a unique role in the control of DDR1 dimerization and autophosphorylation.	Nitrogen	21-22	discoidin domain receptor tyrosine kinase 1	Homo sapiens	99-103
26348848-4	2015	Western blots revealed that wild type Kv3.1a and Kv1.1 alpha-subunits had complex and oligomannose N-glycans, respectively, and that abolishment of the N-glycosylation site(s) generated Kv proteins without N-glycans.	Nitrogen	99-100	potassium voltage-gated channel subfamily A member 1	Homo sapiens	49-54
26309907-6	2015	Rates of AcCoA hydrolysis were between 0.25 - 1% of the rates for N-acetylation of PABA catalyzed by human NAT1 and its rodent orthologs.	Nitrogen	66-67	N-acetyltransferase 1	Homo sapiens	107-111
24509848-10	2014	Taken together, these data suggest that N-glycosylation at the highly conserved (211)NDS motif evolved to act as a negative repressor of DDR1 phosphorylation in the absence of ligand.	Nitrogen	40-41	discoidin domain receptor tyrosine kinase 1	Homo sapiens	137-141
7713919-7	1995	Based on these results we suggest that TC II-R is synthesized as a single polypeptide of 45 kDa, and following its maturation (involving N- and O-glycosylation) the 62-kDa mature receptor is expressed in plasma membranes as a noncovalent dimer of 124 kDa.	Nitrogen	137-138	transcobalamin 2	Homo sapiens	39-44
24471499-4	2014	The study lead to the discovery of a roster of glycoproteins with aberrant N-glycosylation level associated with pancreatic cancer, including mucin-5AC (MUC5AC), carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), insulin-like growth factor binding protein (IGFBP3), and galectin-3-binding protein (LGALS3BP).	Nitrogen	75-76	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	142-151
24471499-4	2014	The study lead to the discovery of a roster of glycoproteins with aberrant N-glycosylation level associated with pancreatic cancer, including mucin-5AC (MUC5AC), carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), insulin-like growth factor binding protein (IGFBP3), and galectin-3-binding protein (LGALS3BP).	Nitrogen	75-76	CEA cell adhesion molecule 5	Homo sapiens	221-228
24471499-4	2014	The study lead to the discovery of a roster of glycoproteins with aberrant N-glycosylation level associated with pancreatic cancer, including mucin-5AC (MUC5AC), carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), insulin-like growth factor binding protein (IGFBP3), and galectin-3-binding protein (LGALS3BP).	Nitrogen	75-76	insulin like growth factor binding protein 3	Homo sapiens	275-281
24471499-4	2014	The study lead to the discovery of a roster of glycoproteins with aberrant N-glycosylation level associated with pancreatic cancer, including mucin-5AC (MUC5AC), carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), insulin-like growth factor binding protein (IGFBP3), and galectin-3-binding protein (LGALS3BP).	Nitrogen	75-76	galectin 3 binding protein	Homo sapiens	288-314
24471499-4	2014	The study lead to the discovery of a roster of glycoproteins with aberrant N-glycosylation level associated with pancreatic cancer, including mucin-5AC (MUC5AC), carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), insulin-like growth factor binding protein (IGFBP3), and galectin-3-binding protein (LGALS3BP).	Nitrogen	75-76	galectin 3 binding protein	Homo sapiens	316-324
24603354-3	2014	Here, we identify the glucose-responsive Sks1p kinase as a signaling protein required for pseudohyphal growth induced by nitrogen limitation and coupled nitrogen/glucose limitation.	Nitrogen	121-129	putative serine/threonine protein kinase SKS1	Saccharomyces cerevisiae S288C	41-46
24603354-3	2014	Here, we identify the glucose-responsive Sks1p kinase as a signaling protein required for pseudohyphal growth induced by nitrogen limitation and coupled nitrogen/glucose limitation.	Nitrogen	153-161	putative serine/threonine protein kinase SKS1	Saccharomyces cerevisiae S288C	41-46
24584735-5	2014	Pulse chase and mutational analysis indicated that HRD1 inhibits STT3B-dependent post-translational N-glycosylation of ABCG8.	Nitrogen	100-101	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	65-70
26093036-0	2015	A novel phosphorylation site of N-methyl-D-aspartate receptor GluN2B at S1284 is regulated by Cdk5 in neuronal ischemia.	Nitrogen	32-33	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	Mus musculus	62-68
26013584-5	2015	Introduction of an aliphatic amine chain on the N atom of the phenothiazine B ring (promazine) conferred inhibitory activity toward NOX2, NOX4, and NOX5 but not NOX1 and NOX3.	Nitrogen	48-49	NADPH oxidase 5	Homo sapiens	148-152
7897657-1	1995	The DNA methyltransferases, M.HhaI and M.TaqI, and catechol O-methyl-transferase (COMT) catalyze the transfer of a methyl group from the cofactor S-adenosyl-L-methionine (AdoMet) to carbon-5 of cytosine, to nitrogen-6 of adenine, and to a hydroxyl group of catechol, respectively.	Nitrogen	207-215	catechol-O-methyltransferase	Homo sapiens	51-80
23999926-2	2014	Uniformly (13)C- and (15)N-labeled CB2 receptor was expressed in milligram quantities by bacterial fermentation, purified, and functionally reconstituted into liposomes.	Nitrogen	25-26	cannabinoid receptor 2	Homo sapiens	35-38
24398691-4	2014	Two intracellular enzymes, UDP-N-acetylglucosamine-polypeptide beta-N-acetylglucosaminyl transferase (OGT) and O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase (OGA), mediate addition and removal, respectively, of N-acetylglucosamine (GlcNAc) from intracellular protein substrates.	Nitrogen	31-32	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	102-105
24605085-5	2014	In the present study, we provide evidence that TRPM4 and TRPM5 are each N-linked glycosylated at a unique residue, Asn(992) and Asn(932), respectively.	Nitrogen	72-73	transient receptor potential cation channel subfamily M member 4	Homo sapiens	47-52
24605085-6	2014	N-linked glycosylated TRPM4 is also found in native cardiac cells.	Nitrogen	0-1	transient receptor potential cation channel subfamily M member 4	Homo sapiens	22-27
24605085-11	2014	Altogether, these results demonstrate that TRPM4 and TRPM5 are both N-linked glycosylated at a unique site and also suggest that TRPM4/5 glycosylation seems not to be involved in channel trafficking, but mainly in their functional regulation.	Nitrogen	68-69	transient receptor potential cation channel subfamily M member 4	Homo sapiens	43-48
7897657-1	1995	The DNA methyltransferases, M.HhaI and M.TaqI, and catechol O-methyl-transferase (COMT) catalyze the transfer of a methyl group from the cofactor S-adenosyl-L-methionine (AdoMet) to carbon-5 of cytosine, to nitrogen-6 of adenine, and to a hydroxyl group of catechol, respectively.	Nitrogen	207-215	catechol-O-methyltransferase	Homo sapiens	82-86
7876230-0	1995	Zone mapping of the binding domain of the rat low affinity nerve growth factor receptor by the introduction of novel N-glycosylation sites.	Nitrogen	117-118	nerve growth factor receptor	Rattus norvegicus	46-87
23924956-4	2014	A novel mutant mouse (Ndst1(-/-)) was developed, having podocyte-specific deletion of Ndst1, the enzyme responsible for N-sulfation of heparan sulfate chains.	Nitrogen	22-23	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	Mus musculus	86-91
23917429-8	2014	Although N-glycosylation of alpha1, beta1, and beta2 were all changed in schizophrenia, the concentrations of GABAAR subunits themselves were unchanged.	Nitrogen	9-10	adrenoceptor alpha 1D	Homo sapiens	28-52
7532677-9	1995	Asparagine 86, the single site of N-linked glycosylation on class I molecules, is in close proximity to the Bw4/Bw6 region.	Nitrogen	34-35	BW6	Homo sapiens	112-115
24563201-7	2014	Like other atg mutants, ATG11-deficient plants senesce prematurely and are hypersensitive to nitrogen and fixed-carbon limitations.	Nitrogen	93-101	meiotically up-regulated protein	Arabidopsis thaliana	24-29
7852339-8	1995	Finally, analysis of a furin mutant, in which all three potential sites for N-linked glycosylation were altered, revealed autocatalytic cleavage, substrate processing, and transport to the Golgi.	Nitrogen	76-77	furin, paired basic amino acid cleaving enzyme	Homo sapiens	23-28
24485462-5	2014	Specifically, the nitrogen mustard cyclophosphamide induces an acute secretory activating phenotype (ASAP), releasing CCL4, IL8, VEGF, and TNFalpha from treated tumor cells.	Nitrogen	18-26	C-C motif chemokine ligand 4	Homo sapiens	118-122
7837273-5	1995	In Ala68 deoxymyoglobin, as in the wild-type protein, a water molecule hydrogen-bonded to the N epsilon atom of the distal histidine restricts ligand binding and appears to be more important in regulating the function of myoglobin than direct steric interactions between the ligand and the C gamma atoms of the native valine side-chain.	Nitrogen	94-95	myoglobin	Physeter catodon	14-23
24211487-1	2014	In the present study, the conversion of fuel-N to HCN and NH3 was investigated during rapid pyrolysis of raw biomass (coconut fiber), its corresponding biochar and their blends with lignite within a temperature range of 600-900 C. The results showed that the raw biomass and the biochar showed totally different nitrogen partitioning between NH3 and HCN.	Nitrogen	312-320	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	50-53
24211487-2	2014	HCN was the dominant nitrogen pollutant from pyrolysis of raw biomass, while for the biochar pyrolysis the yield of NH3 was slightly higher than that of HCN.	Nitrogen	21-29	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	0-3
25036121-2	2014	We found that the decrease of vacuolar basic amino acids in response to nitrogen starvation was impaired by the deletion of AVT4 gene encoding a vacuolar transporter.	Nitrogen	72-80	Avt4p	Saccharomyces cerevisiae S288C	124-128
25024866-0	2014	Quasireversible Process of Dopamine on Copper-Nickel Hydroxide Composite/Nitrogen Doped Graphene/Nafion Modified GCE and Its Electrochemical Application.	Nitrogen	73-81	aminomethyltransferase	Homo sapiens	113-116
7814381-5	1995	Furthermore, based on its changed mobility from 76 to 60 kDa after endoglycosidase H digestion Cne1p was shown to be N-glycosylated.	Nitrogen	117-118	calnexin	Saccharomyces cerevisiae S288C	95-100
25484062-1	2014	CTLA4-Ig is a highly glycosylated therapeutic fusion protein that contains multiple N- and O-glycosylation sites.	Nitrogen	84-85	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	0-5
7798155-1	1995	The cellular level and activity of the general amino acid permease, the product of the GAP1 gene of Saccharomyces cerevisiae, are regulated at the level of transcription by two systems, the products of URE2/GLN3 and NIL1 in response to the nitrogen sources of the growth medium and inactivation in response to the presence of glutamine or glutamate.	Nitrogen	240-248	Gat1p	Saccharomyces cerevisiae S288C	216-220
24474630-2	2014	Here, we report that the selective depletion of Rubisco and cytochrome b6f complex that occurs when Chlamydomonas reinhardtii is starved for nitrogen in the presence of acetate and under normoxic conditions is accompanied by a marked increase in chlororespiratory enzymes, which converts the photosynthetic thylakoid membrane into an intracellular matrix for oxidative catabolism of reductants.	Nitrogen	141-149	cytochrome b	Chlamydomonas reinhardtii	60-72
7846162-3	1994	In hypoxic seedlings with the roots in solution sparged with 5% (v/v) O2 (balance N2) and the shoots in the same gaseous atmosphere, mRNAs for Pdc1 and Adh2 in root tips both increased about 15-fold during the first 12 h, followed by a decline toward initial levels by 18 to 24h.	Nitrogen	82-84	alcohol dehydrogenase 2	Zea mays	152-156
25495764-2	2014	Studies showed that recombinant cellular PrP, PrP(C), expressed in Escherichia coli lacks N-glycosylation and an glycophosphatidyl inositol anchor (GPI) and therefore may not be the most suitable substrate in seeded PMCA reactions to recapitulate prion conversion in vitro.	Nitrogen	90-91	major prion protein	Ovis aries	41-44
7966144-1	1994	Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding.	Nitrogen	36-45	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)	Homo sapiens	20-29
24329062-3	2013	The equilibrium structure is linear HCN-H2 with the nitrogen pointing towards H2 at an intermolecular separation of 7.20 a0.	Nitrogen	52-60	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	36-39
7851160-8	1994	Cells cryopreserved in liquid nitrogen for 1 week before processing showed &lt; 5% loss of PCNA and p120 fluorescence compared to freshly processed cells, but p105 fluorescence dropped 29% in cryopreserved MDA cells.	Nitrogen	30-38	catenin delta 1	Homo sapiens	100-104
7932578-5	1994	This heterocyclic nitrogen atom would provide a critical hydrogen-bond interaction with the histidine residue of the catalytic triad in PEP.	Nitrogen	18-26	prolyl endopeptidase	Homo sapiens	136-139
7520996-1	1994	Sensitivity of yeast cells to the bifunctional alkylating agent nitrogen mustard (HN2) depends on two independently operating physiological mechanisms of cellular metabolism: dynamics of uptake of HN2 via choline permease, encoded in the gene HNM1/CTR, and repair of HN2-induced DNA damage.	Nitrogen	64-72	MT-RNR2 like 2 (pseudogene)	Homo sapiens	82-85
7520996-1	1994	Sensitivity of yeast cells to the bifunctional alkylating agent nitrogen mustard (HN2) depends on two independently operating physiological mechanisms of cellular metabolism: dynamics of uptake of HN2 via choline permease, encoded in the gene HNM1/CTR, and repair of HN2-induced DNA damage.	Nitrogen	64-72	MT-RNR2 like 2 (pseudogene)	Homo sapiens	197-200
8062822-5	1994	The predicted Mep1p protein shares high sequence similarity with several bacterial proteins of unknown function, notably the product of the nitrogen-regulated nrgA gene of Bacillus subtilis, and with that of a partial cDNA sequence derived from Caenorhabditis elegans.	Nitrogen	140-148	ammonium permease MEP1	Saccharomyces cerevisiae S288C	14-19
8062822-7	1994	The MEP1 gene is most highly expressed when the cells are grown on low concentrations of ammonium or on "poor" nitrogen sources like urea or proline.	Nitrogen	111-119	ammonium permease MEP1	Saccharomyces cerevisiae S288C	4-8
7517934-1	1994	Nodulin 26 is an integral symbiosome membrane protein of nitrogen-fixing soybean nodules.	Nitrogen	57-65	nodulin-26	Glycine max	0-10
26008190-3	2015	In three contrasting accessions of A. thaliana, namely Col-0, Tsu-0 and Sha, root hairs were differentially affected by the nitrogen forms and their concentration.	Nitrogen	124-132	SH2 domain protein A	Arabidopsis thaliana	62-75
26218460-4	2015	Several N-methylated analogues are selective and potent agonists or antagonists for hMC1R or hMC5R or have selective antagonist activity for hMC3R.	Nitrogen	8-9	melanocortin 1 receptor	Homo sapiens	84-89
26291458-11	2015	In stark contrast, we found that all four predicted N-glycosylation sites on murine Smo were dispensable for proper trafficking, agonist binding and canonical signal induction.	Nitrogen	52-53	smoothened, frizzled class receptor	Mus musculus	84-87
8007970-8	1994	Thus, the pps1-1 mutation may generate a nitrogen limitation signal, which when coupled with elm4-1 results in pseudohyphal growth even in rich medium.	Nitrogen	41-49	tyrosine/serine/threonine protein phosphatase PPS1	Saccharomyces cerevisiae S288C	10-14
26177091-3	2015	Homologation to the corresponding diene analogues yielded a mixture of Z,E and E,E isomers; substitution of the indoline nitrogen with an N-benzyl group resulted in increased binding to alpha-syn and reasonable selectivity for alpha-syn versus Abeta and tau.	Nitrogen	121-129	synuclein alpha	Homo sapiens	186-195
26177091-3	2015	Homologation to the corresponding diene analogues yielded a mixture of Z,E and E,E isomers; substitution of the indoline nitrogen with an N-benzyl group resulted in increased binding to alpha-syn and reasonable selectivity for alpha-syn versus Abeta and tau.	Nitrogen	121-129	synuclein alpha	Homo sapiens	227-236
8175735-6	1994	Most notably, the level of N-sulfation and 2-O-sulfation is higher, and 6-O-sulfation lower, in syndecan-1 heparan sulfate from MPC-11 than from P3.	Nitrogen	27-28	syndecan 1	Mus musculus	96-106
25761782-6	2015	Here we use hydrogen/deuterium exchange (HDX) mass spectrometry (MS) for probing the conformational dynamics of the model protein myoglobin (Mb) in the presence of N(2) bubbles.	Nitrogen	164-165	myoglobin	Homo sapiens	130-139
25828800-8	2015	The effects of N/OFQ and PWT2-N/OFQ were sensitive to the N/OFQ receptor (NOP) antagonist SB-612111, but not to opioid receptor antagonists.	Nitrogen	15-16	crystallin, gamma B	Mus musculus	58-72
7908696-1	1994	A number of O- and N-alkylated derivatives of the antinociceptive, orally active, mu-opioid-selective truncated enkephalin analog L-2,6-dimethyltyrosyl-N-(3-phenylpropyl)-D-alaninamide (2, SC-39566) were synthesized to explore the structure-activity relationships of the series.	Nitrogen	19-20	immunoglobulin kappa variable 3-15	Homo sapiens	130-133
25828800-8	2015	The effects of N/OFQ and PWT2-N/OFQ were sensitive to the N/OFQ receptor (NOP) antagonist SB-612111, but not to opioid receptor antagonists.	Nitrogen	15-16	crystallin, gamma B	Mus musculus	74-77
25951228-11	2015	The expression levels of P2X3 receptors and IMD in L4/L5 DRG in the CCI+NS and CCI+IMD1-53 groups were significantly increased compared with those in the Control group or the Sham group.	Nitrogen	72-74	purinergic receptor P2X 3	Rattus norvegicus	25-29
25951228-11	2015	The expression levels of P2X3 receptors and IMD in L4/L5 DRG in the CCI+NS and CCI+IMD1-53 groups were significantly increased compared with those in the Control group or the Sham group.	Nitrogen	72-74	adrenomedullin 2	Rattus norvegicus	44-47
25922528-2	2015	A traditional model of ABP bioactivation, based on in vitro enzyme kinetic evidence, had postulated initial N-hydroxylation by the cytochrome P450 isoform CYP1A2.	Nitrogen	108-109	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	155-161
25922528-5	2015	Competing ABP detoxification pathways can include N-acetylation by arylamine N-acetyltransferase 1 (NAT1) and/or NAT2; however, wild-type and Nat1/2(-/-) mice have similar in vivo ABP clearance rates.	Nitrogen	50-51	N-acetyl transferase 1	Mus musculus	67-98
25922528-5	2015	Competing ABP detoxification pathways can include N-acetylation by arylamine N-acetyltransferase 1 (NAT1) and/or NAT2; however, wild-type and Nat1/2(-/-) mice have similar in vivo ABP clearance rates.	Nitrogen	50-51	N-acetyl transferase 1	Mus musculus	100-104
25922528-7	2015	In the present study, we detected similar reductions in Vmax for ABP N-hydroxylation by liver microsomes from Cyp1a2(-/-) and Cyp2e1(-/-) mice when compared with wild-type mice.	Nitrogen	69-70	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	110-116
25922528-7	2015	In the present study, we detected similar reductions in Vmax for ABP N-hydroxylation by liver microsomes from Cyp1a2(-/-) and Cyp2e1(-/-) mice when compared with wild-type mice.	Nitrogen	69-70	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	126-132
8183238-12	1994	The CCK-AR, which has three potential sites for N-glycosylation on the amino-terminal extracellular domain and one on the second extracytoplasmic loop, was deglycosylated to a 42-kDa peptide.	Nitrogen	48-49	cholecystokinin A receptor	Rattus norvegicus	4-10
7912541-6	1994	In FSGS, NAG excretion correlated with the following: blood urea nitrogen (BUN) (r = 0.8), serum protein (r = 0.57), serum cholesterol (r = 0.85), serum albumin (r = -0.68) and proteinuria (r = 0.56).	Nitrogen	65-73	O-GlcNAcase	Homo sapiens	9-12
8145237-9	1994	The results were that the amide nitrogen approaches relatively close to the heme iron in CYP1A1 (3.64 +/- 0.51 A) whereas it is significantly further away (&gt; 4.5 A) in CYP2B1.	Nitrogen	32-40	cytochrome P450, family 2, subfamily b, polypeptide 1	Rattus norvegicus	171-177
8118934-2	1994	Thus the burden of genotoxic metabolites of 4-ABP in a target organ is probably influenced by the balance of N-hydroxylation and alternative metabolic pathways in the hepatocyte.	Nitrogen	109-110	amine oxidase, copper containing 1	Rattus norvegicus	46-49
8118934-3	1994	In freshly isolated rat hepatocytes, 4-ABP (at a substrate concentration of 10 microM) was mainly N-acetylated (54% of total metabolites), while 2% N-hydroxy-4-ABP-N-glucuronide and 21% of unconjugated N-hydroxylated metabolites were detectable.	Nitrogen	98-99	amine oxidase, copper containing 1	Rattus norvegicus	39-42
7832633-2	1994	We have constructed a mutant HIV-1 infectious clone lacking a signal for N-linked glycosylation in the V1-loop of HIV-1 gp120.	Nitrogen	73-74	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	120-125
7874194-1	1994	In enteric bacteria, the transcription of the Ntr regulon is regulated by a signal transduction system that measures and transmits information on the nitrogen status of the cell.	Nitrogen	150-158	neurotensin receptor 1	Homo sapiens	46-49
24142515-0	2013	Disruption of N-linked glycosylation promotes proteasomal degradation of the human ATP-binding cassette transporter ABCA3.	Nitrogen	14-15	ATP binding cassette subfamily A member 3	Homo sapiens	116-121
24142515-2	2013	The first luminal loop of ABCA3 contains three putative N-linked glycosylation sites at residues 53, 124, and 140.	Nitrogen	56-57	ATP binding cassette subfamily A member 3	Homo sapiens	26-31
24142515-10	2013	These results suggest that cotranslational N-linked glycosylation at N124 and N140 is critical for ABCA3 stability, and its disruption results in protein destabilization and proteasomal degradation.	Nitrogen	43-44	ATP binding cassette subfamily A member 3	Homo sapiens	99-104
8218172-0	1993	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	Nitrogen	14-15	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	82-87
24227656-2	2013	All complex and hybrid N-glycosylation requires MGAT1 (UDP-GlcNAc:alpha-3-D-mannoside-beta1,2-N-acetylglucosaminyl-transferase I) function, and Mgat1 nulls are the most compromised N-glycosylation condition that survive long enough to permit synaptogenesis studies.	Nitrogen	23-24	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	48-53
24227656-2	2013	All complex and hybrid N-glycosylation requires MGAT1 (UDP-GlcNAc:alpha-3-D-mannoside-beta1,2-N-acetylglucosaminyl-transferase I) function, and Mgat1 nulls are the most compromised N-glycosylation condition that survive long enough to permit synaptogenesis studies.	Nitrogen	23-24	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	144-149
24227656-2	2013	All complex and hybrid N-glycosylation requires MGAT1 (UDP-GlcNAc:alpha-3-D-mannoside-beta1,2-N-acetylglucosaminyl-transferase I) function, and Mgat1 nulls are the most compromised N-glycosylation condition that survive long enough to permit synaptogenesis studies.	Nitrogen	62-63	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	48-53
24227656-2	2013	All complex and hybrid N-glycosylation requires MGAT1 (UDP-GlcNAc:alpha-3-D-mannoside-beta1,2-N-acetylglucosaminyl-transferase I) function, and Mgat1 nulls are the most compromised N-glycosylation condition that survive long enough to permit synaptogenesis studies.	Nitrogen	62-63	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	144-149
8218172-1	1993	We report the complete structures of the N-linked oligosaccharides and the site-specificity of the N-glycosylation of recombinant gp120 (rgp120) of the HIV-1 BH8 isolate produce by a baculovirus expression system.	Nitrogen	41-42	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	130-135
8403225-1	1993	Nitrogen mustard (HN2) and quinacrine mustard (QM) both inhibited the binding of NF kappa B to the GC-rich consensus sequence in the HIV long terminal repeat (LTR), as assessed by gel-shift assays.	Nitrogen	0-8	MT-RNR2 like 2 (pseudogene)	Homo sapiens	18-21
8347597-4	1993	The human recombinant HGF produced by the insect cells is N-glycosylated, binds to heparin like native HGF, and is recognized by polyclonal antiserums raised against human or rabbit HGF as assessed by immunoblot, ELISA, and immunoneutralization experiments.	Nitrogen	58-59	hepatocyte growth factor	Homo sapiens	22-25
24013186-3	2013	The purpose of the current study was to characterize the N-acetylation of etamicastat by N-acetyltransferases (NAT1 and NAT2) and evaluate potential species differences in etamicastat N-acetylation using a sensitive and specific liquid chromatography-mass spectrometry assay.	Nitrogen	57-58	N-acetyltransferase 1	Homo sapiens	111-115
24189523-0	2013	Glutamate dehydrogenase isoenzyme 3 (GDH3) of Arabidopsis thaliana is regulated by a combined effect of nitrogen and cytokinin.	Nitrogen	104-112	glutamate dehydrogenase 3	Arabidopsis thaliana	0-35
24189523-0	2013	Glutamate dehydrogenase isoenzyme 3 (GDH3) of Arabidopsis thaliana is regulated by a combined effect of nitrogen and cytokinin.	Nitrogen	104-112	glutamate dehydrogenase 3	Arabidopsis thaliana	37-41
24189523-5	2013	The induction and regulation of GDH3 activity in the leaves and roots was investigated following nitrogen deprivation in the presence or absence of sucrose or kinetin.	Nitrogen	97-105	glutamate dehydrogenase 3	Arabidopsis thaliana	32-36
24218570-1	2013	The assembly of the three neuronal soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) proteins synaptobrevin 2, syntaxin-1A, and SNAP-25 is the key step that leads to exocytotic fusion of synaptic vesicles.	Nitrogen	43-44	syntaxin 1A	Homo sapiens	146-157
24218570-1	2013	The assembly of the three neuronal soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) proteins synaptobrevin 2, syntaxin-1A, and SNAP-25 is the key step that leads to exocytotic fusion of synaptic vesicles.	Nitrogen	43-44	synaptosome associated protein 25	Homo sapiens	163-170
24057089-2	2013	The unit was used for the solid-phase peptide synthesis (SPPS) of the N-acetylglucosaminylated emmprin (35-69) thioester via one-step deprotection by TFA combined with the N-alkylcysteine thioesterification method.	Nitrogen	70-71	basigin (Ok blood group)	Homo sapiens	95-102
8337828-10	1993	No evidence of O- or N-linked glycosylation of the OpMNPV p25 was found.	Nitrogen	0-1	p25	Orgyia pseudotsugata multiple nucleopolyhedrovirus	58-61
24036269-1	2013	Addition of N-linked glycosylation sites has been shown to increase serum half-life and decrease clearance for proteins such as recombinant erythropoietin (EPO).	Nitrogen	12-13	erythropoietin	Rattus norvegicus	140-154
24036269-1	2013	Addition of N-linked glycosylation sites has been shown to increase serum half-life and decrease clearance for proteins such as recombinant erythropoietin (EPO).	Nitrogen	12-13	erythropoietin	Rattus norvegicus	156-159
8323299-1	1993	The lysosomal membrane glycoproteins lamp-1 and lamp-2 are extensively glycosylated with a variety of different carbohydrate structures of both N-linked and O-linked type.	Nitrogen	144-145	lysosomal associated membrane protein 1	Homo sapiens	37-43
23746056-0	2013	The nitrogen cycle in anaerobic methanotrophic mats of the Black Sea is linked to sulfate reduction and biomass decomposition.	Nitrogen	4-12	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	65-68
23746056-3	2013	Here, we link the anaerobic oxidation of methane (AOM) to the nitrogen cycle in microbial mats of the Black Sea by using stable isotope probing.	Nitrogen	62-70	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	108-111
23746056-13	2013	Results show that AOM coupled to sulfate reduction along with biomass decomposition drive the nitrogen cycle in the ANME mats of the Black Sea and that MCR enzymes are involved in this process.	Nitrogen	94-102	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	139-142
8104124-13	1993	Although we were unable to reconstitute the N-demethylation activity with purified CYP3A1, which is difficult to reconstitute, collectively the evidence demonstrated that CYP3A enzymes catalyze N-demethylation in PB and PCN microsomes.	Nitrogen	194-195	cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1	Rattus norvegicus	83-89
24214398-10	2013	Under As toxicity, the overexpression lines showed minimal changes in de novo Glu synthesis, while the ggct2;1 mutant increased nitrogen assimilation by severalfold, resulting in a very low As/N ratio in tissue.	Nitrogen	128-136	ChaC-like family protein	Arabidopsis thaliana	103-110
24214398-10	2013	Under As toxicity, the overexpression lines showed minimal changes in de novo Glu synthesis, while the ggct2;1 mutant increased nitrogen assimilation by severalfold, resulting in a very low As/N ratio in tissue.	Nitrogen	193-194	ChaC-like family protein	Arabidopsis thaliana	103-110
25639459-1	2015	The human cytosolic branched-chain aminotransferase (hBCATc) enzyme is strategically located in glutamatergic neurons, where it is thought to provide approximately 30% of de novo nitrogen for brain glutamate synthesis.	Nitrogen	179-187	branched chain amino acid transaminase 1	Homo sapiens	53-59
8360850-2	1993	The characteristic structure of PT-A was examined by nitrogen adsorption/desorption, X-ray diffraction, deviation microscopy, and scanning electron microscopy to establish a pore structural model of PT-A.	Nitrogen	53-61	pre T cell antigen receptor alpha	Homo sapiens	32-36
25887260-4	2015	Independent components analysis revealed that the latent factors that accounted for MFN activity to such changes also accounted for activity associated with the error-related negativity and the NoGo inhibitory N2.	Nitrogen	210-212	reticulon 4	Homo sapiens	194-198
26057350-6	2015	Both the structural sequence and modeling studies demonstrated that clade B gp120 in V1-V4, alpha -2 and N-glycosylated sites are distinct from clade C gp120.	Nitrogen	105-106	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	76-81
25721215-1	2015	BACKGROUND: Like many voltage-gated sodium channels, the cardiac isoform Nav1.5 is well known as a glycoprotein which necessarily undergoes N-glycosylation processing during its transit to the plasma membrane.	Nitrogen	8-9	sodium voltage-gated channel alpha subunit 5	Homo sapiens	73-79
25721215-11	2015	GENERAL SIGNIFICANCE: This work highlights that N-linked glycosylation processing would be critical for Nav1.5 membrane trafficking and function.	Nitrogen	2-3	sodium voltage-gated channel alpha subunit 5	Homo sapiens	104-110
25686600-2	2015	Abiotic processes including hydrothermal reduction, photochemical reactions, or lightning discharge could have converted atmospheric N2 into assimilable NH4(+), HCN, or NOx species, collectively termed fixed nitrogen.	Nitrogen	133-135	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	161-164
25686600-2	2015	Abiotic processes including hydrothermal reduction, photochemical reactions, or lightning discharge could have converted atmospheric N2 into assimilable NH4(+), HCN, or NOx species, collectively termed fixed nitrogen.	Nitrogen	208-216	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	161-164
25713076-4	2015	In vitro, the molybdoenzymes mitochondrial amidoxime reducing component 1 and 2 (mARC1 and mARC2) have shown to be capable of reducing N-hydroxylated base analogs and nucleoside analogs to the corresponding canonical nucleobases and nucleosides upon reconstitution with the electron transport proteins cytochrome b5 and NADH-cytochrome b5 reductase.	Nitrogen	135-136	cytochrome b5 type A	Homo sapiens	302-315
25713076-4	2015	In vitro, the molybdoenzymes mitochondrial amidoxime reducing component 1 and 2 (mARC1 and mARC2) have shown to be capable of reducing N-hydroxylated base analogs and nucleoside analogs to the corresponding canonical nucleobases and nucleosides upon reconstitution with the electron transport proteins cytochrome b5 and NADH-cytochrome b5 reductase.	Nitrogen	135-136	cytochrome b5 type A	Homo sapiens	325-338
25759281-2	2015	In this work, we designed and synthesized a novel n-n heterojunction photocatalyst, namely CdS-ZnWO4 heterojunctions, in which ZnWO4 has more negative conduction band and more positive valence band than those of CdS.	Nitrogen	50-53	CDP-diacylglycerol synthase 1	Homo sapiens	91-94
25759281-2	2015	In this work, we designed and synthesized a novel n-n heterojunction photocatalyst, namely CdS-ZnWO4 heterojunctions, in which ZnWO4 has more negative conduction band and more positive valence band than those of CdS.	Nitrogen	50-53	CDP-diacylglycerol synthase 1	Homo sapiens	212-215
25886826-2	2015	The main GS are classified as cytosolic GS1 and plastidial GS2, of which the functionality is variable according to the nitrogen sources, organs and developmental stages.	Nitrogen	120-128	glutamine synthetase, chloroplastic	Zea mays	59-62
25836296-11	2015	For the orientation of the LEP with respect to the P=S group, the anti orientation was found to be a general rule for N atoms, with the corresponding bond-angle sums deviating by more than 8  from the planar value of 360 .	Nitrogen	118-119	leptin	Homo sapiens	27-30
25281001-3	2015	Here, we present the backbone and side-chain assignment of the (1)H, (13)C and (15)N resonances of RRM2 of La protein from Dictyostelium discoideum.	Nitrogen	83-84	ribonucleotide reductase regulatory subunit M2	Homo sapiens	99-103
25504047-6	2015	This integrin-beta1 N-glycosylation pattern was correlated with higher levels of membrane-bound integrin-beta1 and also with increased binding to fibronectin.	Nitrogen	20-21	integrin beta 1 (fibronectin receptor beta)	Mus musculus	5-19
25504047-6	2015	This integrin-beta1 N-glycosylation pattern was correlated with higher levels of membrane-bound integrin-beta1 and also with increased binding to fibronectin.	Nitrogen	20-21	integrin beta 1 (fibronectin receptor beta)	Mus musculus	96-110
26020207-6	2015	Exceptions to this were in the regression of calf preweaning ADG on the natural logarithm of somatic cell count (SCC) and milk urea nitrogen (MUN).	Nitrogen	132-140	ADG	Bos taurus	61-64
25877353-5	2015	The number of CD14+TLR4+ monocytes was positively correlated with estimated glomerular filtration rate (eGFR, P&lt;0.001) and the levels of hematocrit (P&lt;0.01), but negatively correlated with the levels of blood urine nitrogen, serum creatinine, and C-reactive protein (P&lt;0.001 for all), in the CKD patients.	Nitrogen	221-229	toll like receptor 4	Homo sapiens	19-23
25652878-7	2015	The rate of N-positive disease according to tumour stage ranged from 4.8 %/11.4 % (ypT0/pT1) to 42.1 %/64.1 % (ypT4/pT4).	Nitrogen	12-13	zinc finger protein 77	Homo sapiens	88-91
26269017-1	2015	OBJECTIVE: To investigate the relationship between (GT)n polymorphism and esophageal cancer by analyzing the connection between microsatellite polymorphisms in the promoter of heme oxygenase-1 and the clinicopathological characteristics of esophageal squamous cell carcinoma (ESCC) in Han chinese population.	Nitrogen	15-16	heme oxygenase 1	Homo sapiens	176-192
25205209-3	2015	There were ten adults with N-GD3 treated with imiglucerase in the county of Norrbotten in June 2009.	Nitrogen	27-28	glucosylceramidase beta	Homo sapiens	46-58
25512609-10	2015	Furthermore, we show that the deletion of Gln3p and Gat1p transcription factors, which are activated in response to nitrogen availability, led to abnormal LD dynamics.	Nitrogen	116-124	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-47
25494936-5	2015	Here, we reveal a cell signaling function for a truncated hemoglobin of Chlamydomonas that affects the nitrogen assimilation pathway by simultaneously modulating NO levels and nitrate reductase (NR) activity.	Nitrogen	103-111	uncharacterized protein	Chlamydomonas reinhardtii	176-193
25494936-5	2015	Here, we reveal a cell signaling function for a truncated hemoglobin of Chlamydomonas that affects the nitrogen assimilation pathway by simultaneously modulating NO levels and nitrate reductase (NR) activity.	Nitrogen	103-111	uncharacterized protein	Chlamydomonas reinhardtii	195-197
25494936-6	2015	First, we found that THB1 and THB2 expression is modulated by the nitrogen source and depends on NIT2, a transcription factor required for nitrate assimilation genes expression.	Nitrogen	66-74	uncharacterized protein	Chlamydomonas reinhardtii	30-34
25531508-4	2015	The use of Lyk, of which the side chain is elongated by one CH2 unit so that its chain length to the terminal nitrogen of amine is set to be equal to that of arginine, allowed us to resolve key chemical factors in the Arg finger catalysis, i.e., chain length matching and chemical properties of the terminal groups.	Nitrogen	110-118	IL2 inducible T cell kinase	Homo sapiens	11-14
25488989-2	2015	In particular, we evaluated the role of potential N-glycosylation motifs acquired by somatic hypermutation (ac-Nglycs) within Ig H chain V region (IGHV) genes as alternative selective pressures for B cells in pSS.	Nitrogen	50-51	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	147-151
24038880-7	2013	Our data suggest that N-methylation of Rpt1 and/or its PK sequence might be important in cell growth or stress tolerance in yeast.	Nitrogen	22-23	proteasome regulatory particle base subunit RPT1	Saccharomyces cerevisiae S288C	39-43
24044616-0	2013	Comment on "Modeling nitrous oxide production during biological nitrogen removal via nitrification and denitrification: extensions to the general asm models".	Nitrogen	64-72	H19 imprinted maternally expressed transcript	Homo sapiens	146-149
24044636-0	2013	Reply to comment on "Modeling nitrous oxide production during biological nitrogen removal via nitrification and denitrification: extensions to the general asm models".	Nitrogen	73-81	H19 imprinted maternally expressed transcript	Homo sapiens	155-158
24155687-11	2013	However, it is also suggested that OFQ/N may operate in an anxiolytic manner when initial anxiogenic triggers (eg., the neuropeptide CRH) are initiated.	Nitrogen	39-40	corticotropin releasing hormone	Homo sapiens	133-136
23614645-0	2013	Formation of HCN+ in heterogeneous reactions of N2(+) and N+ with surface hydrocarbons.	Nitrogen	48-53	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	13-16
23614645-1	2013	A significant increase of the ion yield at m/z 27 in collisions of low-energy ions of N2(+) and N(+) with hydrocarbon-covered room-temperature or heated surfaces of tungsten, carbon-fiber composite, and beryllium, not observed in analogous collisions of Ar(+), is ascribed to the formation of HCN(+) in heterogeneous reactions between N2(+) or N(+) and surface hydrocarbons.	Nitrogen	86-88	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	293-296
23614645-1	2013	A significant increase of the ion yield at m/z 27 in collisions of low-energy ions of N2(+) and N(+) with hydrocarbon-covered room-temperature or heated surfaces of tungsten, carbon-fiber composite, and beryllium, not observed in analogous collisions of Ar(+), is ascribed to the formation of HCN(+) in heterogeneous reactions between N2(+) or N(+) and surface hydrocarbons.	Nitrogen	86-87	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	293-296
23892195-10	2013	The lack of SphK1 and the inhibition of S1P lyase by THI were accompanied by modulation in cardiac S1PR1 and S1PR2 expression and by selective changes in plasma N-palmitoyl- and N-behenoyl-ceramide levels.	Nitrogen	161-162	sphingosine-1-phosphate receptor 1	Mus musculus	40-43
23746680-5	2013	With better CdS dispersion and expanded interlayer distance of HNb3O8, the CdS/SiO2-HNb3O8 sample prepared by the novel impregnation-gas phase deposition method showed better activity than the counterpart prepared by conventional liquid phase deposition, CdS-pillared HNb3O8, and some reference samples such as P25, nitrogen-doped TiO2, and Bi2WO6.	Nitrogen	316-324	CDP-diacylglycerol synthase 1	Homo sapiens	75-78
23746680-5	2013	With better CdS dispersion and expanded interlayer distance of HNb3O8, the CdS/SiO2-HNb3O8 sample prepared by the novel impregnation-gas phase deposition method showed better activity than the counterpart prepared by conventional liquid phase deposition, CdS-pillared HNb3O8, and some reference samples such as P25, nitrogen-doped TiO2, and Bi2WO6.	Nitrogen	316-324	CDP-diacylglycerol synthase 1	Homo sapiens	75-78
23417743-6	2013	Sequential hTERT knockdown and APG treatment significantly downregulated expression of hTERT so as to cause over 90 % inhibition of cell invasion and 70 % induction of apoptosis in both SK-N-DZ and SK-N-BE2 cell lines.	Nitrogen	188-190	telomerase reverse transcriptase	Homo sapiens	11-16
23417743-6	2013	Sequential hTERT knockdown and APG treatment significantly downregulated expression of hTERT so as to cause over 90 % inhibition of cell invasion and 70 % induction of apoptosis in both SK-N-DZ and SK-N-BE2 cell lines.	Nitrogen	188-190	telomerase reverse transcriptase	Homo sapiens	87-92
23820740-8	2013	The NR1, NR2A, NR2B, GluR6, and KA2 subunits were all sensitive to treatment with Endo H and PNGase F. The GluR6 KA receptor subunit was significantly more sensitive to Endo H-mediated deglycosylation in schizophrenia, suggesting a larger molecular mass of N-linked high mannose and/or hybrid sugars on GluR6.	Nitrogen	4-5	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	21-26
23820740-8	2013	The NR1, NR2A, NR2B, GluR6, and KA2 subunits were all sensitive to treatment with Endo H and PNGase F. The GluR6 KA receptor subunit was significantly more sensitive to Endo H-mediated deglycosylation in schizophrenia, suggesting a larger molecular mass of N-linked high mannose and/or hybrid sugars on GluR6.	Nitrogen	4-5	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	107-112
23820740-8	2013	The NR1, NR2A, NR2B, GluR6, and KA2 subunits were all sensitive to treatment with Endo H and PNGase F. The GluR6 KA receptor subunit was significantly more sensitive to Endo H-mediated deglycosylation in schizophrenia, suggesting a larger molecular mass of N-linked high mannose and/or hybrid sugars on GluR6.	Nitrogen	4-5	glutamate ionotropic receptor kainate type subunit 2	Homo sapiens	107-112
23092637-10	2013	CONCLUSIONS: The PCK1 rs2179706 polymorphism interacts with plasma concentration of n - 3 PUFA levels modulating insulin resistance in MetS subjects.	Nitrogen	46-47	phosphoenolpyruvate carboxykinase 1	Homo sapiens	17-21
24191539-6	2013	The enrichment results of NH(+) -N, NO2(-) -N, NO3(-)-N, PO4(3-) -P, SiO3(2-)-Si and DIN showed that the sea-surface microlayer displayed an apparent enrichment for nutrients except NO3(-) -N, and the mean enrichment factors ranged from 1.37 to 2.21.	Nitrogen	28-34	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	105-108
24191539-6	2013	The enrichment results of NH(+) -N, NO2(-) -N, NO3(-)-N, PO4(3-) -P, SiO3(2-)-Si and DIN showed that the sea-surface microlayer displayed an apparent enrichment for nutrients except NO3(-) -N, and the mean enrichment factors ranged from 1.37 to 2.21.	Nitrogen	50-55	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	105-108
23767880-2	2013	To provide homogeneous and stable structures with this motif, the synthesis of a C-linked mimic, C-GlcNAc Ser, has been prepared from the C-Glc Ser by a double inversion strategy using azide to insert the C-2 nitrogen functionality.	Nitrogen	209-217	complement C2	Homo sapiens	205-208
23611809-0	2013	Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4.	Nitrogen	53-54	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	6-44
23611809-1	2013	Recent observations revealed that human UDP-glucuronosyltransferase (UGT) 2B10 catalyzes N-glucuronidation of amine-containing compounds.	Nitrogen	89-90	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	40-78
23611809-4	2013	Using recombinant UGT2B10, we found that it catalyzes the N-glucuronidation of amitriptyline, imipramine, ketotifen, pizotifen, olanzapine, diphenhydramine, tamoxifen, ketoconazole, and midazolam.	Nitrogen	58-59	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	18-25
22968690-4	2013	Our objective was to determine how the interplay between M and X in each molecule affects the sigma-holes of both, and consequently their interactions with the nitrogen lone pair of HCN.	Nitrogen	160-168	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	182-185
23947041-1	2013	In this study, we present a nanofiltration (NF90, NF270) pretreatment to increase the precision of dissolved organic nitrogen (DON) measurements in water samples.	Nitrogen	117-125	interleukin enhancer binding factor 3	Homo sapiens	44-48
23947041-3	2013	And the effects on the removal of dissolved inorganic nitrogen (DIN) by NF90 and NF270 were compared.	Nitrogen	54-62	interleukin enhancer binding factor 3	Homo sapiens	72-76
23666577-4	2013	O-demethylation is catalyzed by the highly polymorphic CYP2D6 and N-demethylation by several enzymes, CYP2C19, CYP2C9, and CYP3A4.	Nitrogen	66-67	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	111-117
23666577-5	2013	The observed overall pharmacokinetic effect was most probably the result of decreased N-demethylation of venlafaxine by (1) reduced expression of CYP2C19 due to a genetic deficit and (2) inhibition of CYP2C9 by cotrimoxazole.	Nitrogen	86-87	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	201-207
23556518-0	2013	N-linked glycosylation is required for transferrin-induced stabilization of transferrin receptor 2, but not for transferrin binding or trafficking to the cell surface.	Nitrogen	0-1	transferrin receptor 2	Homo sapiens	76-98
23556518-4	2013	Human TfR2 (hTfR2) contains four potential Asn-linked (N-linked) glycosylation sites on its ectodomain.	Nitrogen	55-56	transferrin receptor 2	Homo sapiens	6-10
23556518-4	2013	Human TfR2 (hTfR2) contains four potential Asn-linked (N-linked) glycosylation sites on its ectodomain.	Nitrogen	55-56	transferrin receptor 2	Homo sapiens	12-17
23556518-6	2013	In this study, by employing site-directed mutagenesis to remove glycosylation sites of hTfR2 individually or in combination, we found that hTfR2 was glycosylated at Asn 240, 339, and 754, while the consensus sequence for N-linked glycosylation at Asn 540 was not utilized.	Nitrogen	221-222	transferrin receptor 2	Homo sapiens	139-144
23522834-2	2013	By optimizing both the N-8 substituent and the biaryl region of the inhibitors we obtained single digit nanomolar compounds such as 37 with excellent selectivity for Plk-2 over Plk-1.	Nitrogen	23-24	polo-like kinase 1	Rattus norvegicus	177-182
23536634-7	2013	The reactivity to N-terminal vimentin of IgG FL Igs was significantly higher than that of IgM FL Igs (30.4 versus 10%; p = 0.0022).	Nitrogen	18-19	vimentin	Homo sapiens	29-37
23434133-3	2013	Most N-substituted analogs exhibited good in vitro activity, and compound 18o (IC50=1.55 nM) was identified to be a potent dipeptidyl peptidase IV inhibitor with a significantly improved pharmacokinetic properties (bioavailablity: 41% vs 82.9%; T1/2: 2h vs 4.9h).	Nitrogen	5-6	dipeptidyl peptidase 4	Homo sapiens	123-146
23371966-4	2013	It also, however, is subject to direct N-glucuronidation by UDP-glucuronosyltransferase 1A4 (UGT1A4).	Nitrogen	39-40	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	60-91
23371966-4	2013	It also, however, is subject to direct N-glucuronidation by UDP-glucuronosyltransferase 1A4 (UGT1A4).	Nitrogen	39-40	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	93-99
25377500-3	2015	In contrast, N(2) ,N(4) -dibenzylquinazoline-2,4-diamine (DBeQ) targets both the D1 and D2 domains and shows only a four- to sixfold decrease in potency against the p97-p47 complex.	Nitrogen	13-17	melanotransferrin	Homo sapiens	165-168
25377500-3	2015	In contrast, N(2) ,N(4) -dibenzylquinazoline-2,4-diamine (DBeQ) targets both the D1 and D2 domains and shows only a four- to sixfold decrease in potency against the p97-p47 complex.	Nitrogen	13-17	pleckstrin	Homo sapiens	169-172
8327483-2	1993	The precursor of rainbow trout TSH beta consists of 147 aa, which can be cleaved into a signal peptide (20 aa) and a mature protein (127 aa) containing one potential N-glycosylation site and 12 cysteine residues.	Nitrogen	166-167	thyrotropin subunit beta	Oncorhynchus mykiss	31-39
23250914-1	2013	Mutations affecting the N-glycosylation site in Berardinelli-Seip lipodystrophy (BSCL)-associated gene BSCL2/seipin lead to a dominantly inherited spastic paraplegia termed seipinopathy.	Nitrogen	24-25	BSCL2 lipid droplet biogenesis associated, seipin	Danio rerio	103-108
23250914-1	2013	Mutations affecting the N-glycosylation site in Berardinelli-Seip lipodystrophy (BSCL)-associated gene BSCL2/seipin lead to a dominantly inherited spastic paraplegia termed seipinopathy.	Nitrogen	24-25	BSCL2 lipid droplet biogenesis associated, seipin	Danio rerio	109-115
23705431-1	2013	As one of the most important components of soil liutrient, it is necessary to obtain the soil total nitrogen(STN)content in precision agriculture.	Nitrogen	100-108	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	109-112
23291264-6	2013	Urinary CCL2 excretion significantly increased approximately 3-fold compared with controls the day after cisplatin administration (5mg/kg), when no changes were observed plasma creatinine and blood urea nitrogen levels.	Nitrogen	203-211	C-C motif chemokine ligand 2	Rattus norvegicus	8-12
8505333-18	1993	Thus, the vast majority of the N-linked glycosylation in the ER of alg3 yeast (&gt; 75%) occurs by transfer of Man5GlcNAc2 without prior addition of the 3 glucoses normally found on the lipid-linked precursor.	Nitrogen	31-32	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	67-71
23158502-0	2013	A novel Delta(1)-pyrroline-5-carboxylate synthetase gene of Medicago truncatula plays a predominant role in stress-induced proline accumulation during symbiotic nitrogen fixation.	Nitrogen	161-169	delta-1-pyrroline-5-carboxylate synthase	Medicago truncatula	8-51
23269669-0	2013	Site-specific N-linked glycosylation of receptor guanylyl cyclase C regulates ligand binding, ligand-mediated activation and interaction with vesicular integral membrane protein 36, VIP36.	Nitrogen	14-15	lectin, mannose binding 2	Homo sapiens	142-180
23269669-0	2013	Site-specific N-linked glycosylation of receptor guanylyl cyclase C regulates ligand binding, ligand-mediated activation and interaction with vesicular integral membrane protein 36, VIP36.	Nitrogen	14-15	lectin, mannose binding 2	Homo sapiens	182-187
8490167-9	1993	These results indicate that the N-linked sugar of EPO-R is not involved in the manifestation of two classes of binding sites, and that there is a yet unidentified glycoprotein crucial for the ligand-saturation characteristics of EPO-R.	Nitrogen	32-33	erythropoietin receptor	Mesocricetus auratus	50-55
23434661-7	2013	This indicates that the CO(2) separation performance of the CMCS/PEI blend membrane is higher than that of other facilitated transport membranes reported for CO(2)/N(2) mixture separation.	Nitrogen	164-168	G protein signaling modulator 2	Homo sapiens	60-64
8474154-4	1993	Protein p32 is not glycosylated in spite of the presence of two putative N-glycosylation sites in the deduced amino acid sequence of the polypeptide.	Nitrogen	73-74	inhibitor of growth family member 2	Homo sapiens	8-11
8463339-0	1993	G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.	Nitrogen	20-28	cyclin dependent kinase 2	Homo sapiens	69-73
23129207-4	2013	More striking changes were observed when dfc seedlings were grown under N-limited conditions, including shorter primary roots, fewer lateral roots, higher levels of glycine and carbon-N ratios, and lower N content than those in wild-type seedlings.	Nitrogen	72-73	DHFS-FPGS homolog C	Arabidopsis thaliana	41-44
23129207-7	2013	The observation that elevated CO(2) partly rescued the dfc phenotypes suggests that the alterations in N metabolism in dfc may be mainly due to a defect in photorespiration.	Nitrogen	103-104	DHFS-FPGS homolog C	Arabidopsis thaliana	55-58
23129207-7	2013	The observation that elevated CO(2) partly rescued the dfc phenotypes suggests that the alterations in N metabolism in dfc may be mainly due to a defect in photorespiration.	Nitrogen	103-104	DHFS-FPGS homolog C	Arabidopsis thaliana	119-122
23129207-8	2013	These results indicate that DFC is required for N utilization in Arabidopsis and provide new insight into a potential interaction between folate and N metabolism.	Nitrogen	48-49	DHFS-FPGS homolog C	Arabidopsis thaliana	28-31
23129207-8	2013	These results indicate that DFC is required for N utilization in Arabidopsis and provide new insight into a potential interaction between folate and N metabolism.	Nitrogen	149-150	DHFS-FPGS homolog C	Arabidopsis thaliana	28-31
8483452-2	1993	Transcription of IME1 is detected under conditions which are known to induce initiation of meiosis, namely starvation for nitrogen and glucose, and the presence of MATa1 and MAT alpha 2 gene products.	Nitrogen	122-130	transcription factor IME1	Saccharomyces cerevisiae S288C	17-21
23184930-2	2013	This negative regulation is achieved by the formation of Ure2-Gln3 and -Gat1 complexes that are thought to sequester these GATA factors in the cytoplasm of cells cultured in excess nitrogen.	Nitrogen	181-189	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	123-127
8483452-4	1993	Translation of IME1 mRNA is achieved either upon nitrogen starvation, or upon G1 arrest.	Nitrogen	49-57	transcription factor IME1	Saccharomyces cerevisiae S288C	15-19
7680192-4	1993	Only one of the two potential N-glycosylation sites (Asn765-Phe-Ser) in PAM-1 was efficiently utilized by microsomal membranes.	Nitrogen	30-31	Pancreatic morphology QTL 1	Rattus norvegicus	72-77
23085435-0	2013	Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway.	Nitrogen	0-8	BCL2 like 11	Homo sapiens	127-130
8478429-6	1993	While the majority of anti-N bound at the free end of CaD, some antibody molecules were found on F-actin.	Nitrogen	27-28	caldesmon 1	Gallus gallus	54-57
23449327-11	2013	A marked difference in the pH dependency curves between tetramines and pentamines suggested that hSMO favored reactions with a non-protonated secondary nitrogen at the cleavage site.	Nitrogen	152-160	smoothened, frizzled class receptor	Homo sapiens	97-101
23449327-12	2013	The Km and Vmax values for Spm and 3343 at pH 7.0 and 9.0 were consistent with the higher substrate activity of 3343 compared to Spm, as well as with the concept of a non-protonated secondary nitrogen at the cleavage site being preferred, and 3343 was well degraded at a physiological pH by hSMO.	Nitrogen	192-200	smoothened, frizzled class receptor	Homo sapiens	291-295
24018687-3	2013	Site-directed mutational analysis of the consensus N-glycosylation sites of the DDRs revealed that mutations of asparagine 213 of DDR2 and asparagine 211 of DDR1, a conserved N-glycosylation site among vertebrate DDRs, inhibited the generation of the high-molecular-mass isoform.	Nitrogen	51-52	discoidin domain receptor tyrosine kinase 1	Homo sapiens	157-161
8400011-4	1993	Besides, the latter two types demand lipophilic nitrogen substituents (arylalkyl) for dopamine D2 receptor affinity.	Nitrogen	48-56	dopamine receptor D2	Homo sapiens	86-106
24018687-3	2013	Site-directed mutational analysis of the consensus N-glycosylation sites of the DDRs revealed that mutations of asparagine 213 of DDR2 and asparagine 211 of DDR1, a conserved N-glycosylation site among vertebrate DDRs, inhibited the generation of the high-molecular-mass isoform.	Nitrogen	175-176	discoidin domain receptor tyrosine kinase 1	Homo sapiens	157-161
24047137-6	2013	DTIC N-demethylation by the CYP1A1 E161K, E256K, and I458V mutants exhibited Michaelis-Menten kinetics, with decreases in Km that doubled the catalytic efficiency relative to wild-type (P &lt; 0.05).	Nitrogen	5-6	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	28-34
25220016-1	2015	N-glycanase 1 (NGLY1) is a conserved enzyme that is responsible for the deglycosylation of misfolded N-glycosylated proteins in the cytoplasm prior to their proteasome-mediated degradation.	Nitrogen	0-1	N-glycanase 1	Homo sapiens	15-20
8374696-1	1993	Growth hormone has been shown to stimulate muscle protein synthesis, improve nitrogen balance and promote wound healing in a variety of catabolic states.	Nitrogen	77-85	gonadotropin releasing hormone receptor	Rattus norvegicus	0-14
25313402-1	2015	The Saccharomyces cerevisiae Siw14, a tyrosine phosphatase involved in the response to caffeine, participates in regulation of the phosphorylation and intracellular localization of Gln3, a GATA transcriptional activator of nitrogen catabolite repression-sensitive genes.	Nitrogen	223-231	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	181-185
24999994-1	2014	A novel electrochemical biosensing platform for nicotinamide adenine dinucleotide (NAD(+))-dependent dehydrogenase catalysis was designed using the nitrogen-doped graphene (NG), which had properties similar to NADH dehydrogenase (CoI).	Nitrogen	148-156	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	230-233
25253656-4	2014	Km and kcat values were determined for four N-alkyl analogs 2-5 and four aryl halide analogs 6-9 at MAO-A and MAO-B.	Nitrogen	44-45	monoamine oxidase A	Homo sapiens	100-105
24143095-9	2013	PEI-premiR-126 nanoparticles at low nitrogen/phosphate (N/P) ratios resulted in significant knockdown of TOM1 in CFBE41o- cells, with the most significant reduction of 66% in TOM1 expression elicited at an N/P ratio of 1:1 while chitosan-based miR-126 nanomedicines failed to facilitate statistically significant knockdown of TOM1 and both nanoparticles appeared relatively nontoxic.	Nitrogen	36-44	microRNA 126	Homo sapiens	7-14
22820730-0	2013	Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).	Nitrogen	26-34	Janus kinase 2	Mus musculus	174-188
22820730-0	2013	Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).	Nitrogen	26-34	Janus kinase 2	Mus musculus	190-194
8380078-6	1993	Synthesis of both gpI and gpIV included intermediary partially glycosylated forms and mature N- and O-linked final product.	Nitrogen	93-94	glucose-6-phosphate isomerase	Homo sapiens	18-21
25285659-2	2014	The two N atoms in the 2cqn ligand are in trans position in the synthesized cis-1 isomer, while they are in cis position in the cis-2 isomer.	Nitrogen	8-9	suppressor of cytokine signaling 1	Homo sapiens	76-81
8423765-0	1993	Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.	Nitrogen	79-80	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	54-58
25233931-2	2014	We report here on the proportion of nicotine metabolism by cytochrome P450 2A6-catalyzed C-oxidation, UDP-glucuronosyl transferase 2B10 (UGT2B10)-catalyzed N-glucuronidation and flavin monooxygenase 3-catalyzed N-oxidation in five ethnic/racial groups and the role of UGT2B10 genotype on the metabolic patterns observed.	Nitrogen	156-157	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	102-135
25233931-2	2014	We report here on the proportion of nicotine metabolism by cytochrome P450 2A6-catalyzed C-oxidation, UDP-glucuronosyl transferase 2B10 (UGT2B10)-catalyzed N-glucuronidation and flavin monooxygenase 3-catalyzed N-oxidation in five ethnic/racial groups and the role of UGT2B10 genotype on the metabolic patterns observed.	Nitrogen	156-157	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	137-144
25233931-2	2014	We report here on the proportion of nicotine metabolism by cytochrome P450 2A6-catalyzed C-oxidation, UDP-glucuronosyl transferase 2B10 (UGT2B10)-catalyzed N-glucuronidation and flavin monooxygenase 3-catalyzed N-oxidation in five ethnic/racial groups and the role of UGT2B10 genotype on the metabolic patterns observed.	Nitrogen	156-157	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	268-275
1359965-1	1992	N-Glycosylation, biosynthesis and degradation of dipeptidylpeptidase IV (EC 3.4.14.5) (DPP IV) were comparatively studied in primary cultured rat hepatocytes and Morris hepatoma 7777 cells (MH 7777 cells).	Nitrogen	0-1	dipeptidylpeptidase 4	Rattus norvegicus	87-93
25004930-2	2014	In contrast, little is known about Fab-linked N-glycosylation, carried by ~ 20% of IgG.	Nitrogen	46-47	FA complementation group B	Homo sapiens	35-38
1359965-10	1992	By contrast, inhibition of N-glycosylation with tunicamycin resulted into rapid degradation of non-N-glycosylated DPP IV molecules in both cell types.	Nitrogen	27-28	dipeptidylpeptidase 4	Rattus norvegicus	114-120
25263124-0	2014	N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling.	Nitrogen	0-1	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	101-104
1359965-10	1992	By contrast, inhibition of N-glycosylation with tunicamycin resulted into rapid degradation of non-N-glycosylated DPP IV molecules in both cell types.	Nitrogen	99-100	dipeptidylpeptidase 4	Rattus norvegicus	114-120
1359965-11	1992	Non-N-glycosylated DPP IV could not be detected at the cell surface indicating an intracellular proteolytic process soon after biosynthesis.	Nitrogen	0-1	dipeptidylpeptidase 4	Rattus norvegicus	19-25
1418987-8	1992	Sequence comparisons revealed a 75% identity between alpha OGP and a corresponding segment of rabbit rec55 zona protein; beta OGP was a 25-residue glycopeptide characterized by the presence of one N-linked and five O-linked sugar chains and a trypsin-resistant internal arginine residue.	Nitrogen	197-198	oviductal glycoprotein 1	Mus musculus	126-129
25340554-0	2014	The inhibition of N-glycosylation of glycoprotein 130 molecule abolishes STAT3 activation by IL-6 family cytokines in cultured cardiac myocytes.	Nitrogen	18-19	interleukin 6 cytokine family signal transducer	Homo sapiens	37-53
25085507-2	2014	Previous studies in yeast have shown that three GTPases-Gtr1, Gtr2, and Rho1-bind to TORC1 in nitrogen and amino acid starvation conditions to block phosphorylation of the S6 kinase Sch9 and activate protein phosphatase 2A (PP2A).	Nitrogen	94-102	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	56-60
1390645-1	1992	The mechanism of N-tetrazole ring formation at the distal histidyl imidazole of sperm whale myoglobin (Mb) has been studied by nitrogen-15 (15N) NMR spectroscopy by utilizing 15N-labeled cyanogen bromide (BrCN) and azide ion (N3-).	Nitrogen	127-135	myoglobin	Physeter catodon	92-101
25001301-8	2014	The basic nitrogen of the piperidine ring is located in close proximity to D368 of gp120 but it does not form any H-bond or salt bridge, a likely explanation for their nonoptimal antagonist properties.	Nitrogen	10-18	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	83-88
16652938-0	1992	Cytokinin Is Required to Induce the Nitrogen-Dependent Accumulation of mRNAs for Phosphoenolpyruvate Carboxylase and Carbonic Anhydrase in Detached Maize Leaves.	Nitrogen	36-44	carbonic anhydrase	Zea mays	117-135
24959971-7	2014	MPO activity significantly increased in necrotic (AT-N) induced changes in lipid composition of necrotic fat, such as increase in FFA and phospholipid (PL) content, generation of Cl-FFAs and increases in saturated FFAs and in the poly-:mono-unsaturated FFA ratio.	Nitrogen	53-54	myeloperoxidase	Rattus norvegicus	0-3
25001409-1	2014	In Saccharomyces cerevisiae, when a rich nitrogen source such as ammonium is added to the culture medium, the general amino acid permease Gap1p is ubiquitinated by the yeast Nedd4-like ubiquitin ligase Rsp5p, followed by its endocytosis to the vacuole.	Nitrogen	41-49	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	202-207
1322832-5	1992	Our data suggest that the Cdc25 protein controls a nitrogen-specific signalling pathway involving the effector PI-PLC, in addition to the glucose-induced activation of adenylyl cyclase (AC).	Nitrogen	51-59	Ras family guanine nucleotide exchange factor CDC25	Saccharomyces cerevisiae S288C	26-31
24797272-12	2014	Reducing endoglin levels in macrophages, but not in the endothelium, led to improved renal function (hematocrit, blood urea nitrogen) after irradiation.	Nitrogen	124-132	endoglin	Mus musculus	9-17
1382725-10	1992	The evidence was obtained that so called mucin "link protein", 118 kDa glycopeptide, is a N-glycosylated fragment of fibronectin, whereas the supposedly native undegraded mucin isolated by Carlstedt et al.	Nitrogen	90-91	LOC100508689	Homo sapiens	41-46
1317768-7	1992	Glutamine-supplemented parenteral nutrition with or without epidermal growth factor treatment resulted in improved nitrogen balance in septic rats.	Nitrogen	115-123	epidermal growth factor like 1	Rattus norvegicus	60-83
1374468-2	1992	The endothelium-dependent relaxations evoked by acetylcholine, ATP and the calcium ionophore A23187 (which are mediated by the constitutive nitric oxide synthase) were inhibited by calmodulin inhibitors [calmidazolium, W-7 and (N-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide, hydrochloride, fendiline] and by an inhibitor of nitric oxide synthase, nitro L-arginine.	Nitrogen	228-231	calmodulin 1	Rattus norvegicus	181-191
1515367-1	1992	Genomic and gene-specific DNA interstrand cross-links produced by nitrogen mustard (HN2) were measured in the human tumor cell line Colo320HSR.	Nitrogen	66-74	MT-RNR2 like 2 (pseudogene)	Homo sapiens	84-87
1521192-3	1992	One such modification is the presence of acetyl moieties at the C-6 hydroxyl group of N-acetylmuramyl residues, and to date, 11 species of eubacteria, including some important human pathogens, such as Neisseria gonorrhoeae, Proteus mirabilis, and Staphylococcus aureus, are known to possess O-acetylated peptidoglycan.	Nitrogen	86-87	complement C6	Homo sapiens	64-67
1543677-7	1992	The N-demethylated metabolite appeared in plasma at the same time as terbinafine and showed similar prolongations in Tmax and t1/2 alpha with the 500- and 750-mg doses.	Nitrogen	4-5	interleukin 1 receptor like 1	Homo sapiens	126-136
1534688-3	1992	We have investigated whether nitrogen mustard (HN2) interfered with either the formation of MPF or its activation.	Nitrogen	29-37	MT-RNR2 like 2 (pseudogene)	Homo sapiens	47-50
24260614-6	2013	However, when exposed to elevated oxidative stress, additional pathways independent of these three sensor proteins are activated to destroy cyclin C. In addition, N-glycosylation is important for Mtl1 function as mutating the receptor residue (Asn42) or an enzyme required for synthesis of N-acetylglucosamine (Gfa1) reduces sensor activity.	Nitrogen	163-164	glutamine--fructose-6-phosphate transaminase (isomerizing) GFA1	Saccharomyces cerevisiae S288C	311-315
22974464-9	2013	We propose that the N- and C-terminal phosphorylated regions of UPF1 recruit SMG7 to the functional NMD complex, and then SMG7 transports the PTC-containing transcripts into P bodies for degradation.	Nitrogen	20-21	UPF1 RNA helicase and ATPase	Homo sapiens	64-68
1350468-1	1992	Growth hormone administration effects a positive nitrogen balance in part by recycling glutamine nitrogen as glutamate at the expense of ureagenesis.	Nitrogen	49-57	gonadotropin releasing hormone receptor	Rattus norvegicus	0-14
22697171-1	2012	The Arabian Sea oxygen minimum zone (OMZ), the largest suboxic region in the world"s oceans, is responsible for up to half of the global mesopelagic fixed nitrogen (N) loss from the ocean via denitrification and anammox.	Nitrogen	155-163	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	12-15
1729436-9	1992	In contrast, the stimulus-induced expression of Fos immunoreactivity was inhibited, but not abolished, by hexamethonium, which limited the spread of activation within the submucosal plexus and completely prevented expression of Fos immunoreactivity by myenteric neurons in response to mucosal puffs of N2.	Nitrogen	302-304	proto-oncogene c-Fos	Cavia porcellus	48-51
23113538-0	2012	An osmium(III)/osmium(V) redox couple generating Os(V)(O)(OH) center for cis-1,2-dihydroxylation of alkenes with H2O2: Os complex with a nitrogen-based tetradentate ligand.	Nitrogen	137-145	cytokine inducible SH2 containing protein	Homo sapiens	73-78
1729436-14	1992	A subset of dynorphin1-8-immunoreactive submucosal neurons (which are known to costore vasoactive intestinal peptide and to be secretomotor in function) expressed nuclear Fos immunoreactivity in response to cholera toxin, but not puffs of N2.	Nitrogen	239-241	proto-oncogene c-Fos	Cavia porcellus	171-174
1744098-3	1991	The predicted PLP-C amino acid sequence contains seven cysteine residues, three tryptophan residues, and two putative N-linked glycosylation sites.	Nitrogen	118-119	prolactin family 8, subfamily A, member 5	Rattus norvegicus	14-19
22992733-6	2012	Arg82 has been extensively studied as part of the transcriptional complex regulating nitrogen sensing, in particular arginine metabolism.	Nitrogen	85-93	inositol polyphosphate multikinase	Saccharomyces cerevisiae S288C	0-5
1898343-1	1991	Human pancreatic elastase 1 (E1) is a glycoprotein containing two potential N-glycosylation sites, one of which carries a carbohydrate moiety [Wendorf, Geyer, Sziegoleit &amp; Linder (1989) FEBS Lett.	Nitrogen	76-77	chymotrypsin like elastase 1	Homo sapiens	6-27
22995157-3	2012	We hypothesized that genetic deletion of CYP1A1 would reduce vasodilatory responses to n-3 PUFAs, but not the metabolites, and increase blood pressure (BP) due to decreases in NO.	Nitrogen	23-24	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	41-47
23202491-7	2012	Remarkably, an intra-domain NPC1L1-NPC1 chimera bearing only a &amp;#126;130-amino acid N&amp;#8211;terminal region of NPC1 domain C could confer substantial viral receptor activity on NPC1L1.	Nitrogen	28-29	NPC intracellular cholesterol transporter 1	Homo sapiens	35-39
23202491-7	2012	Remarkably, an intra-domain NPC1L1-NPC1 chimera bearing only a &amp;#126;130-amino acid N&amp;#8211;terminal region of NPC1 domain C could confer substantial viral receptor activity on NPC1L1.	Nitrogen	28-29	NPC1 like intracellular cholesterol transporter 1	Homo sapiens	185-191
1820200-1	1991	Glycopeptides representing individual N-glycosylation sites of the heterodimeric glycoprotein hormone human chorionic gonadotrophin (hCG) were obtained from subunits hCG alpha (N-glycosylated at Asn-52 and Asn-78) and hCG beta (N-glycosylated at Asn-13 and Asn-30) by digestion with trypsin and chymotrypsin, respectively.	Nitrogen	38-39	chorionic gonadotropin subunit beta 5	Homo sapiens	81-137
1820200-1	1991	Glycopeptides representing individual N-glycosylation sites of the heterodimeric glycoprotein hormone human chorionic gonadotrophin (hCG) were obtained from subunits hCG alpha (N-glycosylated at Asn-52 and Asn-78) and hCG beta (N-glycosylated at Asn-13 and Asn-30) by digestion with trypsin and chymotrypsin, respectively.	Nitrogen	38-39	chorionic gonadotropin subunit beta 5	Homo sapiens	133-136
1820200-1	1991	Glycopeptides representing individual N-glycosylation sites of the heterodimeric glycoprotein hormone human chorionic gonadotrophin (hCG) were obtained from subunits hCG alpha (N-glycosylated at Asn-52 and Asn-78) and hCG beta (N-glycosylated at Asn-13 and Asn-30) by digestion with trypsin and chymotrypsin, respectively.	Nitrogen	177-178	chorionic gonadotropin subunit beta 5	Homo sapiens	81-137
1820200-1	1991	Glycopeptides representing individual N-glycosylation sites of the heterodimeric glycoprotein hormone human chorionic gonadotrophin (hCG) were obtained from subunits hCG alpha (N-glycosylated at Asn-52 and Asn-78) and hCG beta (N-glycosylated at Asn-13 and Asn-30) by digestion with trypsin and chymotrypsin, respectively.	Nitrogen	177-178	chorionic gonadotropin subunit beta 5	Homo sapiens	81-137
22930071-0	2012	Synthesis of vitamin D3 derivatives with nitrogen-linked substituents at A-ring C-2 and evaluation of their vitamin D receptor-mediated transcriptional activity.	Nitrogen	41-49	complement C2	Homo sapiens	80-83
1865678-1	1991	Growth hormone (hGH) has been reported to improve nitrogen balances and accrue lean mass tissue in stable subjects.	Nitrogen	50-58	gonadotropin releasing hormone receptor	Rattus norvegicus	0-14
23233958-0	2012	[Estimation of the flux of inorganic nitrogen flowing into the East China Sea].	Nitrogen	37-45	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	74-77
23233958-1	2012	The flux of inorganic nitrogen flowing into the East China Sea was estimated based on the systematic analysis of all the pollution sources from 1980-2005.	Nitrogen	22-30	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	59-62
22946557-0	2012	Exploring the molecular mechanism of stabilization of the adhesion domains of human CD2 by N-glycosylation.	Nitrogen	91-92	CD2 molecule	Homo sapiens	84-87
25603260-8	2014	Vegetative mesocosms were found to be less effective at P removal at an HRT of 6 to 12 h but not at an HRT of 24 h. VT Mix had the highest removal of total Kjeldahl nitrogen (TKN), significantly different than the other blends.	Nitrogen	165-173	Mix paired-like homeobox	Homo sapiens	119-122
2061316-10	1991	Inhibition of N-linked glycosylation by tunicamycin causes a complete block in intracellular Tg transport by inducing the formation of biologically irreversible aggregates, suggesting that glycosylation of Tg serves to prevent denaturation of the secretory protein within the ER lumen.	Nitrogen	14-15	thyroglobulin	Homo sapiens	93-95
25157234-7	2014	This strategy, explored over the last two decades, has recently been successful using GST-activated nitrogen mustard (TLK286) and gammaGT-activated arsenic-based (GSAO and Darinaparsin) prodrugs confirming the potential of GSH-conjugates as anticancer drugs.	Nitrogen	100-108	glutathione S-transferase kappa 1	Homo sapiens	86-89
22683540-12	2012	In contrast, Fab contained N, 21%; S1, 43% and S2, 36%.	Nitrogen	27-28	FA complementation group B	Homo sapiens	13-16
22683540-14	2012	Total IgG glycan profile (Fab plus Fc) contained N, 78.5%; S1, 17% and S2, 4.5%.	Nitrogen	49-50	FA complementation group B	Homo sapiens	26-29
22683714-5	2012	The highest C-2 activity was attributed to the presence of non-bonded nitrogen interactions which were absent in C-1 and blocked with butoxycarbonyl (BOC group) in C-3.	Nitrogen	70-78	complement C2	Rattus norvegicus	12-15
22683714-6	2012	The same structural activity analogy was extended to organosulfur compounds and it was observed that compound with non-bonding nitrogen interactions, i.e. C-5 has significantly (p&lt;0.05) higher TPx like activity than C-6 and C-4.	Nitrogen	127-135	complement C5	Rattus norvegicus	155-158
25041474-1	2014	The design and synthesis of a mixed 2-pyridonate-Ta(NMe2)3Cl complex for the direct C-H alkylation adjacent to nitrogen in unprotected secondary amines are reported.	Nitrogen	111-119	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	52-56
22683714-6	2012	The same structural activity analogy was extended to organosulfur compounds and it was observed that compound with non-bonding nitrogen interactions, i.e. C-5 has significantly (p&lt;0.05) higher TPx like activity than C-6 and C-4.	Nitrogen	127-135	complement C6	Rattus norvegicus	219-222
2061316-10	1991	Inhibition of N-linked glycosylation by tunicamycin causes a complete block in intracellular Tg transport by inducing the formation of biologically irreversible aggregates, suggesting that glycosylation of Tg serves to prevent denaturation of the secretory protein within the ER lumen.	Nitrogen	14-15	thyroglobulin	Homo sapiens	206-208
1656980-1	1991	Pulmonary surfactant protein A (SP-A), a main component of lung-specific lipid-protein complex (pulmonary surfactant), is characterized by a collagen-like sequence in its amino terminal half and by N-linked glycosylation.	Nitrogen	198-199	surfactant protein A1	Homo sapiens	0-30
22525010-6	2012	The numbers of potential N-glycosylation sites are variable in major glycoprotein GP5 but are conserved in minor glycoproteins GP2, GP3 and GP4.	Nitrogen	25-26	CD36 molecule	Homo sapiens	140-143
25125978-9	2014	On N2, a higher concentration of osteopontin was found in MG-63 cells.	Nitrogen	3-5	secreted phosphoprotein 1	Homo sapiens	33-44
24337809-0	2014	N-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding.	Nitrogen	0-1	bone morphogenetic protein receptor type 2	Homo sapiens	30-72
24337809-0	2014	N-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding.	Nitrogen	0-1	bone morphogenetic protein receptor type 2	Homo sapiens	74-79
24337809-4	2014	However, all three type 2 BMP receptors (BMPR2, ACVR2A/B) contain consensus N-glycosylation sites in their extracellular domains (ECDs), which could play a role in modulating interaction with ligand.	Nitrogen	76-77	bone morphogenetic protein 1	Homo sapiens	26-29
1656980-1	1991	Pulmonary surfactant protein A (SP-A), a main component of lung-specific lipid-protein complex (pulmonary surfactant), is characterized by a collagen-like sequence in its amino terminal half and by N-linked glycosylation.	Nitrogen	198-199	surfactant protein A1	Homo sapiens	32-36
24337809-4	2014	However, all three type 2 BMP receptors (BMPR2, ACVR2A/B) contain consensus N-glycosylation sites in their extracellular domains (ECDs), which could play a role in modulating interaction with ligand.	Nitrogen	76-77	bone morphogenetic protein receptor type 2	Homo sapiens	41-46
24337809-5	2014	Here, we show a differential pattern of N-glycosylation between BMPR2 and ACVR2A/B.	Nitrogen	40-41	bone morphogenetic protein receptor type 2	Homo sapiens	64-69
22765901-2	2012	Through the optimization of hit compound 1, we discovered that the basic nitrogen atom of bicyclic amine played an important role in GPR119 agonist activity expression and that an indanone in various bicyclic rings was suitable in this series of compounds.	Nitrogen	73-81	G protein-coupled receptor 119	Homo sapiens	133-139
1816977-5	1991	Dephosphorylation of the insulin receptor by alkaline phosphatase resulted in an increase in insulin-stimulated autophosphorylation of the insulin receptor from STZ-D rats (43 +/- 13% to 66 +/- 14%, P less than 0.05), but not from normal rats (100% to 109 +/- 12%, NS).	Nitrogen	265-267	insulin receptor	Rattus norvegicus	25-41
21938481-6	2012	Treatment of differentiating cells with alendronate or pamidronate, nitrogen-containing BPs increase the expression of OPG, which suppresses osteoclastogenesis, whereas it decreases the expression of M-CSF, which enhances preosteoclast formation.	Nitrogen	68-76	colony stimulating factor 1	Homo sapiens	200-205
22820921-5	2012	A two-dimensional (1)H-(15)N HSQC NMR spectrum exhibits fewer number of resonances than expected, suggesting that Tr-HBX is a hybrid type IUP where its folded C-terminal half coexists with a disordered N-terminal region.	Nitrogen	27-28	X protein	Hepatitis B virus	117-120
22678955-12	2012	However, at P&lt;1 atm, the gas-adsorption capacities for N(2) at 77 K and CO(2) at 195 K are higher for noninterpenetrated SNU-70" than for interpenetrated SNU-71", but the capacities for H(2) and CH(4) are the opposite; SNU-71" has higher uptake capacities than SNU-70" due to the higher isosteric heat of gas adsorption that results from the smaller pores.	Nitrogen	58-62	RNA binding motif protein 25	Homo sapiens	157-163
22678955-12	2012	However, at P&lt;1 atm, the gas-adsorption capacities for N(2) at 77 K and CO(2) at 195 K are higher for noninterpenetrated SNU-70" than for interpenetrated SNU-71", but the capacities for H(2) and CH(4) are the opposite; SNU-71" has higher uptake capacities than SNU-70" due to the higher isosteric heat of gas adsorption that results from the smaller pores.	Nitrogen	58-62	RNA binding motif protein 25	Homo sapiens	222-228
22417185-6	2012	Two sequential proton transfers occur: one proton from the C3 position of 2o4hex is initially transferred to the nitrogen atom of the general base, Pro1.	Nitrogen	113-121	lamin A/C	Homo sapiens	148-152
22856306-2	2012	Nitric oxide was found to be reduced to N2 with urea deposited on the ACF and CA.	Nitrogen	40-42	ACF	Homo sapiens	70-73
22937648-5	2012	Split nitrogen application before anthesis increased plant nitrate reductase activity significantly.	Nitrogen	6-14	nitrate reductase [NADH] 1	Zea mays	59-76
22593433-0	2012	Down-regulation of the epidermal growth factor receptor by altering N-glycosylation: emerging role of beta1,4-galactosyltransferases.	Nitrogen	68-69	epidermal growth factor receptor	Cricetulus griseus	23-55
22593433-1	2012	BACKGROUND/AIM: Blocking N-glycosylation of the epidermal growth factor receptor (EGFR) by tunicamycin inhibits its cellular accumulation.	Nitrogen	8-9	epidermal growth factor receptor	Cricetulus griseus	48-80
22593433-1	2012	BACKGROUND/AIM: Blocking N-glycosylation of the epidermal growth factor receptor (EGFR) by tunicamycin inhibits its cellular accumulation.	Nitrogen	8-9	epidermal growth factor receptor	Cricetulus griseus	82-86
23004905-4	2012	Here we present a complementary scheme that is based on the nudged-elastic-band method ordinarily used to find saddle points and we apply the scheme to find the most stable isomers of the phosphorus P(4), P(8) molecules and the corresponding molecules of As(n), Sb(n), and Bi(n) (n = 4,8) in the framework of the density functional theory.	Nitrogen	13-14	solute carrier family 10 member 4	Homo sapiens	199-203
22446090-3	2012	Here we report that N-methylation of 1a greatly increases its potency and results in excellent selectivity for SIRT2 over SIRT1 and SIRT3 isoforms.	Nitrogen	20-21	sirtuin 2	Homo sapiens	111-116
22376051-5	2012	Stabilizing the planarity of this anilide and the nitrogen atom on the six-membered ring of the scaffold was critical for enhancing BRAF inhibition.	Nitrogen	50-58	B-Raf proto-oncogene, serine/threonine kinase	Rattus norvegicus	132-136
22809160-1	2012	Nitrate reductase (NR) and peroxidase (POX) are important enzymes involved in the metabolism of reactive oxygen (ROS) and nitrogen species in leaves of wheat (Triticum aestivum L.) seedlings.	Nitrogen	122-130	peroxidase-like	Triticum aestivum	27-37
22809160-1	2012	Nitrate reductase (NR) and peroxidase (POX) are important enzymes involved in the metabolism of reactive oxygen (ROS) and nitrogen species in leaves of wheat (Triticum aestivum L.) seedlings.	Nitrogen	122-130	peroxidase-like	Triticum aestivum	39-42
22178065-7	2012	Three potential N-glycosylation sites were predicted for mouse PAI-1 (i.e. N209, N265 and N329).	Nitrogen	16-17	serine (or cysteine) peptidase inhibitor, clade E, member 1	Mus musculus	63-68
22541106-7	2012	Multivariate stepwise regression analysis revealed that serum uric acid, creatinine, P-LCR, urea nitrogen contributed to GMP-140 level (adjusted R(2) = 0.822).	Nitrogen	97-105	selectin P	Homo sapiens	121-128
22191536-2	2012	FBP contains multiple N-glycosilation sites, is selectively expressed in tissues and body fluids, and mediates targeted therapies in cancer and inflammatory diseases.	Nitrogen	22-23	folate receptor alpha	Homo sapiens	0-3
22260746-6	2012	NMR data on (15)N-labeled alpha-synuclein show that upon FN075 addition, alpha-synuclein oligomers with 7 nm radius form in which the C-terminal 40 residues remain disordered and solvent exposed.	Nitrogen	0-1	synuclein alpha	Homo sapiens	26-41
22260746-6	2012	NMR data on (15)N-labeled alpha-synuclein show that upon FN075 addition, alpha-synuclein oligomers with 7 nm radius form in which the C-terminal 40 residues remain disordered and solvent exposed.	Nitrogen	0-1	synuclein alpha	Homo sapiens	73-88
22239739-2	2012	Among these, only substrates that have an amide linkage to the C-2 nitrogen were transferred by GlmU to afford their corresponding uridine diphosphate(UDP)-sugar nucleotides.	Nitrogen	67-75	complement C2	Homo sapiens	63-66
22206960-9	2012	The L-N group showed elevated global MMP activity (284%+-71%) and decreased MMP-8 (37%+-17%) and TIMP-4 (48%+-14) activity.	Nitrogen	6-7	matrix metallopeptidase 8	Homo sapiens	76-81
22206960-10	2012	In the R-N group, MMP-7 (46%+-13%) and MMP-8 (36%+-17%) and TIMP-1 (59%+-10%) and TIMP-4 (42%+-5%) were decreased.	Nitrogen	9-10	matrix metallopeptidase 7	Homo sapiens	18-23
22109665-2	2012	METHODS: Cys-tagged EGF (cEGF) was labeled with (18)F by coupling the free thiol group of the Cys tag with N-[2-(4-[(18)F]fluorobenzamido)ethyl]maleimide ([(18)F]FBEM) to form [(18)F]FBEM-cEGF.	Nitrogen	107-113	epidermal growth factor	Homo sapiens	20-23
22041888-2	2012	The X-ray structural analysis exhibits that the three complexes show similar mononuclear structures, in which NIT-2Py radical chelates the Ln(III) ion through the oxygen atom of the NO group and the nitrogen atom from the pyridine ring.	Nitrogen	199-207	nitrilase family member 2	Homo sapiens	110-115
21939780-10	2012	These data indicated that the syndecan-4 cytoplasmic domain and the GAG and N-glycosylated chains are critical in syndecan-4 regulating satellite cell proliferation, responsiveness to FGF2, and PKCalpha cell membrane localization.	Nitrogen	76-77	fibroblast growth factor 2	Meleagris gallopavo	184-188
22449662-6	2012	Serum TRX levels are positively correlated with blood urea nitrogen, serum uric acid and proteinuria, and negatively with estimated glomerular filtration rate (eGFR).	Nitrogen	59-67	thioredoxin	Homo sapiens	6-9
21802953-2	2012	By this approach we identified the N-benzylated beta-proline derivative of tocainide (To10) as the most potent use-dependent blocker of Nav1.4 so far.	Nitrogen	35-36	sodium voltage-gated channel alpha subunit 4	Homo sapiens	136-142
23227176-3	2012	By contrast, Hxt3 is endocytosed and degraded in the vacuole when cells are starved of glucose and Hxt7 in response to rapamycin treatment or when nitrogen is limiting.	Nitrogen	147-155	hexose transporter HXT3	Saccharomyces cerevisiae S288C	13-17
24337809-7	2014	We further demonstrate using a cell-free pulldown assay that N-glycosylation of the BMPR2-ECD enhances its ability to bind BMP2 ligand but has no impact on binding by the closely-related ACVR2B.	Nitrogen	61-62	bone morphogenetic protein receptor type 2	Homo sapiens	84-89
25002508-7	2014	In vitro biochemical studies show that G-CSF programs MPO-EL expression on human blood leukocytes and marrow myeloid cells via induction of N-linked sialofucosylations on MPO, with concomitant cell surface display of the molecule.	Nitrogen	140-141	colony stimulating factor 3	Homo sapiens	39-44
25013459-1	2014	Sequential polymerization of N-carboxyanhydrides accelerated by nitrogen flow is utilized to generate a novel well-defined diblock copolypeptide (PDI = 1.08), with incorporation of alkyne-functionalized side-chain groups allowing for rapid and efficient thiol-yne click-type modifications, followed by self-assembly into nanopure water to construct a helical polypeptide-based versatile and functional nanoparticle platform.	Nitrogen	64-72	peptidyl arginine deiminase 1	Homo sapiens	146-153
24884609-6	2014	Next, we performed glycosidase-assisted LC-MS/MS analysis of ITIH4 trypsin-GluC glycopeptides enriched via hydrophilic interaction liquid chromatography to characterize ITIH4 N-glycoforms.	Nitrogen	0-1	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	61-66
24884609-6	2014	Next, we performed glycosidase-assisted LC-MS/MS analysis of ITIH4 trypsin-GluC glycopeptides enriched via hydrophilic interaction liquid chromatography to characterize ITIH4 N-glycoforms.	Nitrogen	0-1	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	169-174
24884609-7	2014	While microheterogeneity of N-glycoforms differed between ITIH4 protein expressed in HEK293 cells and protein isolated from serum, occupancy of N-glycosylation sites did not differ.	Nitrogen	28-29	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	58-63
24877755-2	2014	The reaction proceeds under catalytic RuH2(CO)(PPh3)3 conditions driven by the activation of the unreactive C-N bond by amide directing group (DG)-Ru catalyst chelation.	Nitrogen	110-111	protein phosphatase 4 catalytic subunit	Homo sapiens	47-51
24892923-5	2014	This growing chemisorbed sulphur- or nitrogen-atom-initiated poly(CO2) chain further displaces physisorbed hydrocarbon, providing a continuous carbon dioxide selectivity.	Nitrogen	37-45	complement C2	Homo sapiens	66-69
24828975-8	2014	The N-demethylation was catalyzed by CYP2B6, CYP2C19, CYP2D6, and CYP3A4, the aromatic hydroxylation by CYP2C19 and CYP2D6, and the aliphatic hydroxylation was catalyzed by CYP1A2, CYP2B6, CYP2C19, and CYP3A4.	Nitrogen	4-5	cytochrome P450, family 2, subfamily b, polypeptide 3	Rattus norvegicus	181-187
24657507-1	2014	Glutamine synthetase (GS) is a key enzyme in nitrogen assimilation, which catalyzes the formation of glutamine from ammonia and glutamate.	Nitrogen	45-53	hypothetical protein	Arabidopsis thaliana	0-20
23119098-5	2012	When grown at higher nitrogen supply, invaders had a plastic RGR response, increasing their RGR to a much greater extent than non-invaders.	Nitrogen	21-29	retinal G protein coupled receptor	Homo sapiens	61-64
23119098-5	2012	When grown at higher nitrogen supply, invaders had a plastic RGR response, increasing their RGR to a much greater extent than non-invaders.	Nitrogen	21-29	retinal G protein coupled receptor	Homo sapiens	92-95
22679498-10	2012	Analysis of the water"s chemistry shows evidence of microbial activity along the path and suggests that the springs supply nitrogen, phosphorus and organic matter to the microbial communities in the Dead Sea.	Nitrogen	123-131	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	204-207
22347385-5	2012	CD138(+) myeloma cells in the BM were reduced by p53-dependent apoptosis following administration of the nitrogen mustard derivative bendamustine to mice in the NOG-hMM model.	Nitrogen	105-113	transformation related protein 53, pseudogene	Mus musculus	49-52
1816977-5	1991	Dephosphorylation of the insulin receptor by alkaline phosphatase resulted in an increase in insulin-stimulated autophosphorylation of the insulin receptor from STZ-D rats (43 +/- 13% to 66 +/- 14%, P less than 0.05), but not from normal rats (100% to 109 +/- 12%, NS).	Nitrogen	265-267	insulin receptor	Rattus norvegicus	139-155
20582095-1	1991	The use of a novel modeless laser as the broadband source in multiplex CARS thermometry, by reducing the laser noise on the CARS spectra, is shown to give a precision of approximately 1 % in single-shot temperature measurements in nitrogen at 1200 K.	Nitrogen	231-239	cysteinyl-tRNA synthetase 1	Homo sapiens	71-75
22829770-0	2012	Mgat1-dependent N-glycosylation of membrane components primes Drosophila melanogaster blood cells for the cellular encapsulation response.	Nitrogen	16-17	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	0-5
20582095-1	1991	The use of a novel modeless laser as the broadband source in multiplex CARS thermometry, by reducing the laser noise on the CARS spectra, is shown to give a precision of approximately 1 % in single-shot temperature measurements in nitrogen at 1200 K.	Nitrogen	231-239	cysteinyl-tRNA synthetase 1	Homo sapiens	124-128
21908519-0	2011	Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.	Nitrogen	96-97	solute carrier family 9 member A9	Homo sapiens	25-31
1993209-2	1991	5-Deazatetrahydrofolate was as good an inhibitor of GARFT as DDATHF, indicating that isosteric replacement of nitrogen by carbon at the 5-position of tetrahydrofolate is sufficient for inhibition of GARFT.	Nitrogen	110-118	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	Homo sapiens	52-57
27468150-3	2011	A series of interleukin-2 inducible T cell kinase (Itk, EC 2.7.10.2) inhibitors that achieve selectivity through the introduction of a single nitrogen atom in an aromatic ring has recently been discovered.	Nitrogen	142-150	IL2 inducible T cell kinase	Homo sapiens	12-49
27468150-3	2011	A series of interleukin-2 inducible T cell kinase (Itk, EC 2.7.10.2) inhibitors that achieve selectivity through the introduction of a single nitrogen atom in an aromatic ring has recently been discovered.	Nitrogen	142-150	IL2 inducible T cell kinase	Homo sapiens	51-54
1993209-2	1991	5-Deazatetrahydrofolate was as good an inhibitor of GARFT as DDATHF, indicating that isosteric replacement of nitrogen by carbon at the 5-position of tetrahydrofolate is sufficient for inhibition of GARFT.	Nitrogen	110-118	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	Homo sapiens	199-204
27468150-4	2011	Structures of these inhibitors bound to Itk showed this nitrogen to be solvent exposed and not involved in any direct interactions with the enzyme.	Nitrogen	56-64	IL2 inducible T cell kinase	Homo sapiens	40-43
1995196-2	1991	Both 2-N- and 5-substituted MeIQx metabolites were recognized by antibodies AIA-2 and AIA-11, while antibodies AIA-1 and AIA-12 bound N-substituted metabolites only.	Nitrogen	7-8	Adjuvant induced arthritis QTL 11	Rattus norvegicus	86-92
22649382-3	2011	Single N-glycosylation mutants at any of the four sites were able to acquire the mature N-glycosylated pattern, but exhibited a decreased Tpo-dependent JAK2-STAT response in stably transduced Ba/F3 or Ba/F3-JAK2 cell lines.	Nitrogen	7-8	Janus kinase 2	Mus musculus	152-156
22649382-3	2011	Single N-glycosylation mutants at any of the four sites were able to acquire the mature N-glycosylated pattern, but exhibited a decreased Tpo-dependent JAK2-STAT response in stably transduced Ba/F3 or Ba/F3-JAK2 cell lines.	Nitrogen	7-8	Janus kinase 2	Mus musculus	207-211
1995196-2	1991	Both 2-N- and 5-substituted MeIQx metabolites were recognized by antibodies AIA-2 and AIA-11, while antibodies AIA-1 and AIA-12 bound N-substituted metabolites only.	Nitrogen	7-8	Adjuvant induced arthritis QTL 1	Rattus norvegicus	86-91
1901843-5	1991	Treatment with GRF increased (P less than .05) digestibility of DM, nitrogen (N), and energy and tended (P less than .20) to increase N retention.	Nitrogen	68-76	growth hormone releasing hormone	Bos taurus	15-18
21942410-2	2011	Upon reconstitution with the electron transport proteins, cytochrome b(5) and its reductase, this molybdenum enzyme is capable of reducing N-hydroxylated compounds.	Nitrogen	139-140	cytochrome b5 type A	Homo sapiens	58-91
21847101-6	2011	Also, Epo-MSCs led to significantly better kidney function as shown by lower levels of blood urea nitrogen (72 +- 9.5 mg/dl versus 131 +- 9.20 mg/dl) and creatinine (74 +- 17 micromol/l versus 148+-19.4 micromol/l).	Nitrogen	98-106	erythropoietin	Mus musculus	6-9
1912302-0	1991	Comparative studies of N-hydroxylation and N-demethylation by microsomal cytochrome P-450.	Nitrogen	23-24	cytochrome P-450	Oryctolagus cuniculus	73-89
21894985-2	2011	Activation of ArNH(2) in many cases starts with N-hydroxylation by P450 enzymes, primarily CYP1A2.	Nitrogen	16-17	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	91-97
21894985-10	2011	The primary drivers for mutagenic potency of ArNH(2) are (i) binding affinity of ArNH(2) in the productive binding mode within the CYP1A2 substrate cavity, (ii) resonance stabilization of the anionic forms of ArNH(2), and (iii) exothermicity of proton-assisted heterolytic cleavage of N-O bonds of hydroxylamines and their bioconjugates.	Nitrogen	47-48	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	131-137
1912302-0	1991	Comparative studies of N-hydroxylation and N-demethylation by microsomal cytochrome P-450.	Nitrogen	43-44	cytochrome P-450	Oryctolagus cuniculus	73-89
1912302-1	1991	The N-hydroxylation of representative aromatic amines by rabbit liver microsomes was mediated by cytochrome P-450 as demonstrated by the sensitivity to carbon monoxide and other cytochrome P-450 inhibitors.	Nitrogen	4-5	cytochrome P-450	Oryctolagus cuniculus	97-113
21752865-4	2011	In support, bioinformatics analysis indicated that BRI2 bears the consensus sequence Asn-Thr-Ser (residues 170-173) and could be N-glycosylated at Asn170.	Nitrogen	129-130	integral membrane protein 2B	Homo sapiens	51-55
21752865-5	2011	Given that N-glycosylation is considered essential for protein folding, processing and trafficking, we examined whether BRI2 is N-glycosylated.	Nitrogen	128-129	integral membrane protein 2B	Homo sapiens	120-124
21752865-6	2011	Treatment of HEK293 (human embryonic kidney) cells expressing BRI2 with the N-glycosylation inhibitor tunicamycin or mutation of Asn170 to alanine reduced its molecular mass by ~2 kDa.	Nitrogen	76-77	integral membrane protein 2B	Homo sapiens	62-66
21752865-7	2011	These data indicate that BRI2 is N-glycosylated at Asn170.	Nitrogen	33-34	integral membrane protein 2B	Homo sapiens	25-29
21621574-9	2011	The protein interaction of BCATm and GDH1 promotes regeneration of PLP-BCATm which then binds to BCKDC resulting in channeling of the BCKA products from BCATm first half reaction to E1 and promoting BCAA oxidation and net nitrogen transfer from BCAAs.	Nitrogen	222-230	glutamate dehydrogenase 1	Homo sapiens	37-41
21621574-10	2011	The cycling of nitrogen through glutamate via the actions of BCATm and GDH1 releases free ammonia.	Nitrogen	15-23	glutamate dehydrogenase 1	Homo sapiens	71-75
1912302-1	1991	The N-hydroxylation of representative aromatic amines by rabbit liver microsomes was mediated by cytochrome P-450 as demonstrated by the sensitivity to carbon monoxide and other cytochrome P-450 inhibitors.	Nitrogen	4-5	cytochrome P-450	Oryctolagus cuniculus	178-194
1646412-6	1991	However, as reported in the literature, there was a significant increase in the N-acetylation of ACTH(1-13)amide during secretion.	Nitrogen	80-81	proopiomelanocortin L homeolog	Xenopus laevis	97-101
21239206-7	2011	The 4-CyP degradation was inhibited in the presence of nitrogen gas owing to the free radical scavenging effect in vapor phase within the bubbles of cavitation.	Nitrogen	55-63	peptidylprolyl isomerase G	Homo sapiens	6-9
21944178-4	2011	Following baseline observations, high intra-abdominal pressure (IAP) with intraperitoneal nitrogen inflation was induced in all 6 pigs.	Nitrogen	90-98	CD47 molecule	Sus scrofa	64-67
2103475-1	1990	It has been documented that when furnished with an endomembrane signal sequence for the endoplasmic reticulum, beta-glucuronidase (GUS) is N-glycosylated, resulting in the nearly complete loss of enzymatic activity.	Nitrogen	139-140	glucuronidase beta	Homo sapiens	111-129
21592713-6	2011	DP-1 arose from decarboxylation of VAL, while DP-2 results from further loss of nitrogen from the tetrazole motif of DP-1, with concomitant cyclization to yield a tetracyclic diazacyclopropene derivative.	Nitrogen	80-88	transcription factor Dp-2	Homo sapiens	46-50
2103475-1	1990	It has been documented that when furnished with an endomembrane signal sequence for the endoplasmic reticulum, beta-glucuronidase (GUS) is N-glycosylated, resulting in the nearly complete loss of enzymatic activity.	Nitrogen	139-140	glucuronidase beta	Homo sapiens	131-134
21788519-0	2011	High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation.	Nitrogen	5-13	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	29-33
2103475-2	1990	To enable use of beta-glucuronidase as a reporter protein in secretory and vacuolar targeting studies, one of the two putative N-linked glycosylation sites within the GUS gene was altered by site-directed mutagenesis.	Nitrogen	127-128	glucuronidase beta	Homo sapiens	17-35
21788519-2	2011	We previously isolated the Arabidopsis high nitrogen-insensitive 9-1 (hni9-1) mutant, impaired in the systemic feedback repression of the root nitrate transporter NRT2.1 by high N supply.	Nitrogen	44-52	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	70-74
21788519-2	2011	We previously isolated the Arabidopsis high nitrogen-insensitive 9-1 (hni9-1) mutant, impaired in the systemic feedback repression of the root nitrate transporter NRT2.1 by high N supply.	Nitrogen	163-164	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	70-74
2103475-2	1990	To enable use of beta-glucuronidase as a reporter protein in secretory and vacuolar targeting studies, one of the two putative N-linked glycosylation sites within the GUS gene was altered by site-directed mutagenesis.	Nitrogen	127-128	glucuronidase beta	Homo sapiens	167-170
21788519-4	2011	HNI9/AtIWS1 acts in roots to repress NRT2.1 transcription in response to high N supply.	Nitrogen	1-2	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	5-11
21788519-6	2011	Repression of NRT2.1 transcription by high N supply is associated with an HNI9/AtIWS1-dependent increase in histone H3 lysine 27 trimethylation at the NRT2.1 locus.	Nitrogen	14-15	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	74-78
2233826-8	1990	From these data we conclude that following 2,4-DAT activation by N-hydroxylation by cytochrome P450, the resulting hydroxylamino intermediate is further activated in the bacteria via O-acetylation to form the ultimate reactive intermediate, which is postulated to be 4-acetoxyamino-2-aminotoluene.	Nitrogen	65-66	solute carrier family 6 member 3	Rattus norvegicus	47-50
21788519-6	2011	Repression of NRT2.1 transcription by high N supply is associated with an HNI9/AtIWS1-dependent increase in histone H3 lysine 27 trimethylation at the NRT2.1 locus.	Nitrogen	14-15	Transcription elongation factor (TFIIS) family protein	Arabidopsis thaliana	79-85
21794015-5	2011	In addition, the relation of IGF-I and its specific binding protein to the nitrogen sparing effect of supplemented methionine was also investigated.	Nitrogen	75-83	insulin like growth factor 1	Gallus gallus	29-34
16667714-3	1990	CA activity was reduced in plants grown under nitrogen deficiency and recovered only slowly when supplemented with nitrate.	Nitrogen	46-54	carbonic anhydrase	Zea mays	0-2
2157764-10	1990	All five potential N-linked glycosylation sites are conserved and six of the seven cysteine residues of the mouse protein are found in the human CD28 polypeptide.	Nitrogen	19-20	CD28 molecule	Homo sapiens	145-149
21490424-7	2011	In addition, we found that Atg13 is gradually rephosphorylated during prolonged nitrogen starvation, and the kinase activity of Atg1 is required for Atg13 rephosphorylation.	Nitrogen	80-88	serine/threonine protein kinase regulatory subunit ATG13	Saccharomyces cerevisiae S288C	27-32
21490424-7	2011	In addition, we found that Atg13 is gradually rephosphorylated during prolonged nitrogen starvation, and the kinase activity of Atg1 is required for Atg13 rephosphorylation.	Nitrogen	80-88	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	27-31
16667412-1	1990	We have utilized the cellular differentiation gradient of the developed, youngest leaf to examine the regulation by nitrogen of levels of phosphoenolpyruvate carboxylase (PEPCase), pyruvate orthophosphate dikinase (PPDK), and ribulose 1,5-bisphosphate carboxylase in maize (Zea mays L.).	Nitrogen	116-124	pyruvate, phosphate dikinase 1, chloroplastic	Zea mays	181-213
21767121-9	2011	Finally, the renal accumulation of HECs in megalin-shedding mice was dramatically reduced by over ~50% as compared with that in normal animals and the specific renal uptake of HECs was increasingly inhibited with the N-acetylation increased.	Nitrogen	217-218	low density lipoprotein receptor-related protein 2	Mus musculus	43-50
24602872-4	2014	Here we report a procedure for the expression of a SUMO-medin fusion protein in Escherichia coli and IMAC purification yielding pure, uniformly (13)C,(15)N-labelled medin in quantities required for SSNMR analysis.	Nitrogen	154-155	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	56-61
24602872-4	2014	Here we report a procedure for the expression of a SUMO-medin fusion protein in Escherichia coli and IMAC purification yielding pure, uniformly (13)C,(15)N-labelled medin in quantities required for SSNMR analysis.	Nitrogen	154-155	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	165-170
24884960-1	2014	BACKGROUND: The tetraspanin CD63 is a highly N-glycosylated protein that is known to regulate cancer malignancy.	Nitrogen	8-9	CD63 molecule	Homo sapiens	28-32
24932134-4	2014	We speculated that the inhibition of STAT3 phosphorylation by glucosamine might be a functional consequence of the reduced N-glycosylation of gp130.	Nitrogen	123-124	interleukin 6 cytokine family signal transducer	Homo sapiens	142-147
24932134-9	2014	RESULTS: In DU145 cells glucosamine reduced the N-glycosylation of gp130, decreased IL-6 binding to cells and impaired the phosphorylation of JAK2, SHP2 and STAT3.	Nitrogen	48-49	interleukin 6 cytokine family signal transducer	Homo sapiens	67-72
21652719-8	2011	Most of the renal injury (both histologically and biochemically as measured by blood urea nitrogen and creatinine) was abolished following HgCl(2) treatment of Oat1 knock-outs.	Nitrogen	90-98	solute carrier family 22 member 6	Homo sapiens	160-164
21762534-3	2011	The dependence of emmprin activity on N-glycosylation is controversial.	Nitrogen	38-39	basigin (Ok blood group)	Homo sapiens	18-25
21762534-8	2011	CONCLUSIONS: Our results indicate that ECI can mimic emmprin activity when substituted with chitobiose, the disaccharide with which N-glycosylation starts.	Nitrogen	2-3	basigin (Ok blood group)	Homo sapiens	53-60
16667412-2	1990	The protein whose level regulated most preferentially by N availability was PEPCase, followed by PPDK, and the changes in level occurred most conspicuously at the photosynthetically maturing cells.	Nitrogen	57-58	pyruvate, phosphate dikinase 1, chloroplastic	Zea mays	97-101
2344273-0	1990	Determining of nitrogen absorption and nitrogen secretion in different sections of the pig"s intestine by digesta exchange between 15N labelled and unlabelled animals.	Nitrogen	15-23	phosphatidylinositol glycan anchor biosynthesis class S	Sus scrofa	87-92
21606496-4	2011	Using a recombinant fusion protein of the extracellular domain of 2B4, we demonstrate that N-linked glycosylation of 2B4 is essential for the binding to its ligand CD48.	Nitrogen	91-92	CD244 molecule	Homo sapiens	66-69
21606496-4	2011	Using a recombinant fusion protein of the extracellular domain of 2B4, we demonstrate that N-linked glycosylation of 2B4 is essential for the binding to its ligand CD48.	Nitrogen	91-92	CD244 molecule	Homo sapiens	117-120
24726727-1	2014	Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues.	Nitrogen	156-164	Protein arginine N-methyltransferase 7	Caenorhabditis elegans	0-36
24726727-1	2014	Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues.	Nitrogen	156-164	Protein arginine N-methyltransferase 7	Caenorhabditis elegans	38-43
24680718-3	2014	By the proposed method both aspects are combined, resulting in balanced results for examples of total nitrogen concentrations in the German Bight/North Sea.	Nitrogen	102-110	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	152-155
21748912-0	2011	Nitrogen washout during a fatty meal while breathing nitrogen-free gas at sea level.	Nitrogen	53-61	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	74-77
1688937-5	1990	Deglycosylation of LAMP indicates that it contains N-linked high mannose or hybrid sugars and a minor amount of sialic acid.	Nitrogen	51-52	limbic system associated membrane protein	Homo sapiens	19-23
21748912-3	2011	METHODS: Nitrogen elimination was measured for 125 min in 10 subjects by gas chromatography while they breathed a normoxic argon-oxygen mixture at sea level.	Nitrogen	9-17	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	147-150
21605551-2	2011	Recent studies revealed that enzyme IIA(Ntr) of the nitrogen PTS regulates the intracellular concentration of K(+) by direct interaction with TrkA and KdpD.	Nitrogen	52-60	colicin Ia immunity protein	Escherichia coli	36-39
24819162-5	2014	Similarly, soil organic carbon (SOC) and total nitrogen (STN) in the 0-50 cm were highest under UG (13.3 kg C m-2 and 1.69 kg N m-2) and lowest under HG (9.8 kg C m-2 and 1.22 kg N m-2).	Nitrogen	47-55	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	57-60
33761993-7	2021	RESULTS: Mice pretreated with G-CSF/AMD3100 exhibited longer survival and lower serum creatinine and blood urea nitrogen (BUN) levels than mice treated with only G-CSF or saline.	Nitrogen	112-120	colony stimulating factor 3 (granulocyte)	Mus musculus	30-35
24334766-0	2014	Dysregulation of T cell receptor N-glycosylation: a molecular mechanism involved in ulcerative colitis.	Nitrogen	33-34	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	17-32
21420927-0	2011	Elucidation of the mechanism of N-demethylation catalyzed by cytochrome P450 monooxygenase is facilitated by exploiting nitrogen-15 heavy isotope effects.	Nitrogen	32-33	cytochrome P450 family 20 subfamily A member 1	Homo sapiens	61-90
21420927-2	2011	Their potential in assisting to describe the mechanism of N-demethylation of tertiary amines by the action of cytochrome P450 monooxygenase has been investigated.	Nitrogen	58-59	cytochrome P450 family 20 subfamily A member 1	Homo sapiens	110-139
33807002-6	2021	The disease is assumed to be a disorder of N-glycosylation given that this is the only known function of the ALG13 protein.	Nitrogen	43-44	ALG13 UDP-N-acetylglucosaminyltransferase subunit	Homo sapiens	109-114
20338588-12	2011	NS infusion had also some favorable effects regarding MDA and MPO.	Nitrogen	0-2	myeloperoxidase	Rattus norvegicus	62-65
24334766-5	2014	We demonstrated that UC patients exhibit a dysregulation of TCR branched N-glycosylation on lamina propria T lymphocytes.	Nitrogen	73-74	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	60-63
33799711-6	2021	The low values of Ep(CO2)-Ep(N2) and Ep(N2) for the BTESE-PNEN membrane at a low concentration of PNEN were close to those of copolymerized BTESE-APTES-related hybrid membranes, which illustrates a potential CO2 separation performance by using a mixed matrix membrane strategy with multiple amine POSS as particles.	Nitrogen	29-31	epiregulin	Homo sapiens	18-20
24552216-4	2014	Because enrichment of Syntaxin 4, a plasma membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein, enhances beta-cell function in mice, we investigated its potential to restore functional insulin secretion to human diabetic islets.	Nitrogen	60-61	syntaxin 4A (placental)	Mus musculus	22-32
21454652-7	2011	Despite its lack of stable association with the latter components, Complex II supported the retrotranslocation and degradation of model ERAD substrates alpha1-antitrypsin null Hong-Kong (NHK) and its variant NHK-QQQ lacking the N-glycosylation sites.	Nitrogen	187-188	adrenoceptor alpha 1D	Homo sapiens	152-158
24198271-10	2014	Added on top of ACE inhibition, ACE + PC (but not ACE + CA) even further prolonged lifespan by additional 18.0% (P &lt; 0.01 versus ACE + PLAC) and improved renal function (blood urea nitrogen; P &lt; 0.05 versus ACE + CA).	Nitrogen	184-192	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	32-35
33799711-6	2021	The low values of Ep(CO2)-Ep(N2) and Ep(N2) for the BTESE-PNEN membrane at a low concentration of PNEN were close to those of copolymerized BTESE-APTES-related hybrid membranes, which illustrates a potential CO2 separation performance by using a mixed matrix membrane strategy with multiple amine POSS as particles.	Nitrogen	29-31	epiregulin	Homo sapiens	26-28
24198271-10	2014	Added on top of ACE inhibition, ACE + PC (but not ACE + CA) even further prolonged lifespan by additional 18.0% (P &lt; 0.01 versus ACE + PLAC) and improved renal function (blood urea nitrogen; P &lt; 0.05 versus ACE + CA).	Nitrogen	184-192	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	32-35
24198271-10	2014	Added on top of ACE inhibition, ACE + PC (but not ACE + CA) even further prolonged lifespan by additional 18.0% (P &lt; 0.01 versus ACE + PLAC) and improved renal function (blood urea nitrogen; P &lt; 0.05 versus ACE + CA).	Nitrogen	184-192	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	32-35
24198271-10	2014	Added on top of ACE inhibition, ACE + PC (but not ACE + CA) even further prolonged lifespan by additional 18.0% (P &lt; 0.01 versus ACE + PLAC) and improved renal function (blood urea nitrogen; P &lt; 0.05 versus ACE + CA).	Nitrogen	184-192	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	32-35
24559458-1	2014	New cyclic and acylic phosphorus-nitrogen compounds have been synthesized in reactions of Hyp-N(SiMe3)PCl2 (hypersilyl = Hyp = (Me3Si)3Si) with silver salts of the perfluorinated anions [CF3CO2](-), [CF3SO3](-), and [C6F5](-).	Nitrogen	33-41	metal response element binding transcription factor 2	Homo sapiens	102-106
21321052-2	2011	Leaves of C(4) crops have increased nitrogen and water use efficiencies compared with C(3) species.	Nitrogen	36-44	complement C4A (Rodgers blood group)	Homo sapiens	10-14
21351767-3	2011	Among these functional PAFs, we found that tetrahydrofuran-like ether-functionalized PAF-1 shows higher adsorption capacity for CO(2) at 1 bar and 298 K (10 mol per kilogram of adsorbent) and also much higher selectivities for CO(2)/CH(4), CO(2)/N(2), and CO(2)/H(2) mixtures when compared with the amine functionality.	Nitrogen	246-250	PAF1 homolog, Paf1/RNA polymerase II complex component	Homo sapiens	85-90
33799711-6	2021	The low values of Ep(CO2)-Ep(N2) and Ep(N2) for the BTESE-PNEN membrane at a low concentration of PNEN were close to those of copolymerized BTESE-APTES-related hybrid membranes, which illustrates a potential CO2 separation performance by using a mixed matrix membrane strategy with multiple amine POSS as particles.	Nitrogen	29-31	epiregulin	Homo sapiens	26-28
21195083-1	2011	The bio-effects of cellular repressor of E1A-stimulated genes (CREG) have been proposed to depend on its N-glycosylation and binding to mannose-6-phosphate/insulin-like growth factor-2 receptor (M6P/IGF2R).	Nitrogen	105-106	insulin like growth factor 2 receptor	Homo sapiens	136-193
21195083-1	2011	The bio-effects of cellular repressor of E1A-stimulated genes (CREG) have been proposed to depend on its N-glycosylation and binding to mannose-6-phosphate/insulin-like growth factor-2 receptor (M6P/IGF2R).	Nitrogen	105-106	insulin like growth factor 2 receptor	Homo sapiens	195-204
24407290-7	2014	Thus, both MPI activity and exogenous mannose concentration determine the metabolic flux into the N-glycosylation pathway.	Nitrogen	98-99	mannose phosphate isomerase	Homo sapiens	11-14
33803174-0	2021	Nitrogen Dissolution in Liquid Ga and Fe: Comprehensive Ab Initio Analysis, Relevance for Crystallization of GaN.	Nitrogen	0-8	gigaxonin	Homo sapiens	109-112
24527664-4	2014	Here, the N-glycosylation profile of 32 pregnant women was determined over the course of their pregnancy using a multiplexed CGE-LIF method.	Nitrogen	10-11	LIF interleukin 6 family cytokine	Homo sapiens	129-132
21295283-5	2011	Zebrafish studies showed virtually identical photoreceptor defects as observed with N-linked glycosylation-interfering mutations in the light-sensing protein rhodopsin.	Nitrogen	84-85	rhodopsin	Danio rerio	158-167
20959627-10	2011	Growing plants in vitro with ammonium or nitrate as the sole nitrogen source allowed us to confirm that GLN1;2 is induced by ammonium in roots and to observe that gln1;2 mutants displayed, under such conditions, longer root hair and smaller rosette phenotypes in ammonium.	Nitrogen	61-69	hypothetical protein	Arabidopsis thaliana	163-169
33801425-7	2021	In general, an appropriate amount of N fertilizer (225 kg/hm2) balanced tea yield and quality.	Nitrogen	37-38	cholinergic receptor muscarinic 2	Homo sapiens	58-61
24503220-9	2014	The largest variation in the amount of carbon and lipids was among ant subfamilies and species, while the largest variation in nitrogen was among ant genera.	Nitrogen	127-135	solute carrier family 25 member 6	Homo sapiens	146-149
21106902-0	2011	ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice.	Nitrogen	9-10	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	Mus musculus	0-6
33236298-4	2021	Total soil N inputs were 194 kg N ha-1 in agricultural systems over China in 2010, including chemical N fertilizer (78%), atmospheric N deposition (12%), and crop residues N (10%).	Nitrogen	11-12	solute carrier family 9 member B1	Homo sapiens	32-38
20621933-9	2011	In ESRD subjects, plasma UII (P=0.008) increased after dialysis, while SBP (P=0.007), DBP (P=0.009), serum creatinine (P&lt;0.0001) and serum urea nitrogen (P&lt;0.0001) decreased.	Nitrogen	147-155	urotensin 2	Homo sapiens	25-28
24338013-3	2014	We report the effects of N-terminal acetylation on alpha-synuclein binding to lipid vesicles of different composition and curvature and to micelles composed of the detergents beta-octyl-glucoside (BOG) and SDS.	Nitrogen	25-26	synuclein alpha	Homo sapiens	51-66
24338013-7	2014	Thus, the naturally occurring N-terminally acetylated form of alpha-synuclein exhibits stabilized helicity at its N terminus and increased affinity for lipid vesicles similar to synaptic vesicles, a binding target of the protein in vivo.	Nitrogen	30-31	synuclein alpha	Homo sapiens	62-77
21184740-2	2011	When this yeast is provided with secondary nitrogen sources, transcription of genes encoding enzymes involved in their catabolism is elicited through the action of Gln3, which constitutes the main activator of the Nitrogen Catabolite Repression network (NCR).	Nitrogen	43-51	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	164-168
32797897-2	2020	In this work, a novel glucose-based nitrogen-doped carbon dots (Glc-NCDs)-bonded silica stationary phase (Sil-Glc-NCDs) was synthesized and characterized carefully.	Nitrogen	36-44	STIL centriolar assembly protein	Homo sapiens	106-109
21184740-2	2011	When this yeast is provided with secondary nitrogen sources, transcription of genes encoding enzymes involved in their catabolism is elicited through the action of Gln3, which constitutes the main activator of the Nitrogen Catabolite Repression network (NCR).	Nitrogen	214-222	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	164-168
21184740-7	2011	Results presented herein show that induced expression of catabolic and biosynthetic genes when cells are grown under nitrogen derepressive conditions and amino acid deprivation is dependent on the concurrent action of Gln3 and Gcn4, which form part of a unique transcriptional complex.	Nitrogen	117-125	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	218-222
21220122-5	2011	However, several lines of evidence point to a concurrent and independent monofunctional hydrolysis of the N-glycosylic bond being the in vivo relevant reaction mode of hOgg1.	Nitrogen	106-107	8-oxoguanine DNA glycosylase	Homo sapiens	168-173
21173255-5	2011	Nitrification is a central process in the nitrogen cycle that produces both the greenhouse gas nitrous oxide and oxidized forms of nitrogen used by phytoplankton and other microorganisms in the sea; at the Bermuda Atlantic Time Series and Hawaii Ocean Time-series sites, experimental acidification decreased ammonia oxidation rates by 38% and 36%.	Nitrogen	42-50	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	194-197
21173255-5	2011	Nitrification is a central process in the nitrogen cycle that produces both the greenhouse gas nitrous oxide and oxidized forms of nitrogen used by phytoplankton and other microorganisms in the sea; at the Bermuda Atlantic Time Series and Hawaii Ocean Time-series sites, experimental acidification decreased ammonia oxidation rates by 38% and 36%.	Nitrogen	131-139	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	194-197
21757827-5	2011	Biochemical and immunofluorescence experiments strongly indicated that YIPF3 is synthesized in the ER as a N-glycosylated form (40 kDa), is then O-glycosylated in the Golgi apparatus to become a lower mobility form (46 kDa) and finally becomes a higher mobility form cleaved at its C-terminal luminal domain (36 kDa).	Nitrogen	107-108	Yip1 domain family member 3	Homo sapiens	71-76
21686172-1	2011	The study aims to present a detailed theoretical investigation of noncovalent intermolecular interactions between different pi-pi stacking nitrogen substituted phenothiazine derivatives by applying second-order Moller-Plesset perturbation (MP2), density functional (DFT) and semiempirical theories.	Nitrogen	139-147	tryptase pseudogene 1	Homo sapiens	240-243
22355701-1	2011	Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an essential component of the immune system, because it trims peptide precursors and generates the N--restricted epitopes.	Nitrogen	149-150	endoplasmic reticulum aminopeptidase 1	Homo sapiens	0-38
22355701-1	2011	Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an essential component of the immune system, because it trims peptide precursors and generates the N--restricted epitopes.	Nitrogen	149-150	endoplasmic reticulum aminopeptidase 1	Homo sapiens	40-45
20937811-9	2010	Critical to increased immunity in ACE 10/10 is the overexpression of iNOS and reactive nitrogen intermediates, as inhibition of iNOS by the inhibitor 1400W eliminated all in vitro and in vivo differences in innate bacterial resistance between ACE 10/10 and WT mice.	Nitrogen	87-95	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	34-37
21240668-2	2010	Dietary supplementation of mannose can reverse clinical symptoms by entering the N-glycosylation pathway downstream of MPI.	Nitrogen	81-82	mannose phosphate isomerase	Homo sapiens	119-122
20204527-7	2010	The synthesis of beta-galactosidase from the PDI2-lacZ fusion gene was markedly enhanced in the Pap1-positive KP1 cells by SNP and nitrogen starvation.	Nitrogen	131-139	regenerating family member 3 alpha	Homo sapiens	96-100
20204527-9	2010	The PDI2 mRNA level was elevated by SNP and nitrogen starvation in the Pap1-positive cells but not in the Pap1-negative cells.	Nitrogen	44-52	regenerating family member 3 alpha	Homo sapiens	71-75
20204527-10	2010	In brief, the S. pombe PDI2 plays a protective role against nitrosative and nutritional stresses, and is positively regulated by NO and nitrogen starvation in a Pap1-dependent manner.	Nitrogen	136-144	regenerating family member 3 alpha	Homo sapiens	161-165
20738805-3	2010	Nitrate reductase enzyme activity is responsible for the reduction of nitrate to nitrite, and nitrate is the major form of nitrogen assimilated in plants.	Nitrogen	123-131	nitrate reductase [NADH] 1	Zea mays	0-17
20848033-5	2010	It was found that the endoglycosidase-catalyzed transglycosylation allowed efficient attachment of an intact N-glycan in a single step at the N-glycosylation site, while the recombinant human T-synthase could independently extend the O-linked GalNAc to form the core 1 O-glycan.	Nitrogen	109-110	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Homo sapiens	192-202
20977356-5	2010	(13)CO(2)-exhalation increased between baseline and week 48 in both supplementation arms as evidenced by a higher delta over baseline excretion at 45 min (from mean +- SEM of 7.8 +- 1.08 to 9.9 +- 0.6, p = 0.04 in the n-acetyl-carnitine arm, and from 7.4 +- 0.8 to 11.5 +- 1.6, p = 0.01 in LA/NAC arm).	Nitrogen	19-20	synuclein alpha	Homo sapiens	293-296
20693288-0	2010	N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.	Nitrogen	0-1	catenin beta 1	Homo sapiens	51-63
20693288-11	2010	Our results provide the first evidence that the Wnt/beta-catenin signaling pathway regulates the metabolic pathway of protein N-glycosylation by targeting DPAGT1 expression.	Nitrogen	126-127	catenin beta 1	Homo sapiens	52-64
20825553-5	2010	Protein N-linked glycosylation was assessed by analysing serum transferrin through mass spectrometry and protein O-linked through isoelectric focusing (IEF) of serum apolipoprotein C-III (apoC-III), confirmed by mass spectrometry.	Nitrogen	8-9	apolipoprotein C3	Homo sapiens	188-196
20686044-2	2010	Antibody neutralization has been shown to be dependent on the presence of N-linked glycosylation at position 160 in gp120.	Nitrogen	74-75	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	116-121
20598727-3	2010	Although we found that the ORF0 of both strains was incorporated into virus particles, the C-terminal region of vOka ORF0 was presented on the virion surface and was N-glycosylated, suggesting that the mutation in vOka ORF0 changes it into a novel envelope glycoprotein.	Nitrogen	166-167	membrane protein UL56	Human alphaherpesvirus 3	117-121
20598727-3	2010	Although we found that the ORF0 of both strains was incorporated into virus particles, the C-terminal region of vOka ORF0 was presented on the virion surface and was N-glycosylated, suggesting that the mutation in vOka ORF0 changes it into a novel envelope glycoprotein.	Nitrogen	166-167	membrane protein UL56	Human alphaherpesvirus 3	117-121
20304108-3	2010	Using solution-state NMR spectroscopy we have assigned the (1)H-(15)N HSQC spectrum of murine LRAP (rp(H)LRAP) in 2% acetic acid at pH 3.0 by making extensive use of previous chemical shift assignments for full-length murine amelogenin (rp(H)M180).	Nitrogen	21-22	amelogenin, X-linked	Mus musculus	94-98
20304108-3	2010	Using solution-state NMR spectroscopy we have assigned the (1)H-(15)N HSQC spectrum of murine LRAP (rp(H)LRAP) in 2% acetic acid at pH 3.0 by making extensive use of previous chemical shift assignments for full-length murine amelogenin (rp(H)M180).	Nitrogen	21-22	amelogenin, X-linked	Mus musculus	100-109
20501912-8	2010	Kinetic analysis of dextromethorphan metabolism indicated that the apparent K(m) and V(max) of CYP2D17 and CYP2D44 catalyzed O-demethylation were similar, and, the V(max) values of CYP2D17 and CYP2D44 catalyzed N-demethylation (which human CYP2D6 catalyzes much less effectively) were similar, but the apparent K(m) of the CYP2D44 reaction was higher.	Nitrogen	211-212	cytochrome P450 family 2 subfamily D member 6	Macaca fascicularis	95-102
20672205-0	2010	Nitrogen retention in the Szczecin Lagoon, Baltic Sea.	Nitrogen	0-8	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	50-53
20225218-2	2010	We recently demonstrated that COL10A1 expression was inhibited in MSCs from patients with osteoarthritis cultured on nitrogen-rich plasma polymerized (PPE:N) coatings.	Nitrogen	117-125	collagen type X alpha 1 chain	Homo sapiens	30-37
20631306-7	2010	Depleting MD-2 using small interfering RNA or blocking the N-glycosylation of cells using tunicamycin blocked membrane trafficking of TLR4.	Nitrogen	40-41	lymphocyte antigen 96	Mus musculus	10-14
20498311-5	2010	Prolonged exposure of HIV-1-infected CEM T-cell cultures with escalating AH concentrations selects for mutant virus strains containing N-glycosylation site deletions (predominantly affecting high-mannose-type glycans) in gp120.	Nitrogen	135-136	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	221-226
20498311-6	2010	In contrast to 2G12, AH has a high genetic barrier, since several concomitant N-glycosylation site deletions in gp120 are required to afford significant phenotypic drug resistance.	Nitrogen	78-79	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	112-117
20460427-4	2010	RESULTS: N-glycosylation of CN-1 was either inhibited by tunicamycin in pCSII-CN-1-transfected Cos-7 cells or by stepwise deletion of its three putative N-glycosylation sites.	Nitrogen	9-10	carnosine dipeptidase 1	Homo sapiens	28-32
20460427-4	2010	RESULTS: N-glycosylation of CN-1 was either inhibited by tunicamycin in pCSII-CN-1-transfected Cos-7 cells or by stepwise deletion of its three putative N-glycosylation sites.	Nitrogen	9-10	carnosine dipeptidase 1	Homo sapiens	78-82
20460427-4	2010	RESULTS: N-glycosylation of CN-1 was either inhibited by tunicamycin in pCSII-CN-1-transfected Cos-7 cells or by stepwise deletion of its three putative N-glycosylation sites.	Nitrogen	29-30	carnosine dipeptidase 1	Homo sapiens	78-82
20460427-13	2010	CONCLUSIONS: We conclude that apart from the (CTG)(n) polymorphism in the signal peptide of CN-1, N-glycosylation is essential for appropriate secretion and enzyme activity.	Nitrogen	2-3	carnosine dipeptidase 1	Homo sapiens	92-96
20568751-4	2010	Instead, our results indicated that HDAC8 employs a proton-shuttle catalytic mechanism, in which a neutral His143 first serves as the general base to accept a proton from the zinc-bound water molecule in the initial rate-determining nucleophilic attack step, and then shuttles it to the amide nitrogen atom to facilitate the cleavage of the amide bond.	Nitrogen	293-301	histone deacetylase 8	Homo sapiens	36-41
20616074-6	2010	The distinct nitrogen incorporations at the elemental abundances of H(2)C(2)N and HCN, respectively, are suggestive of important roles of H(2)C(2)N/HCCN and HCN/CN in their formation.	Nitrogen	13-21	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	82-85
20616074-6	2010	The distinct nitrogen incorporations at the elemental abundances of H(2)C(2)N and HCN, respectively, are suggestive of important roles of H(2)C(2)N/HCCN and HCN/CN in their formation.	Nitrogen	13-21	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	157-160
23985745-7	2014	Significant correlations were observed between N-cycling genes (ureC, gdh and amoA) and nitrous oxide flux, suggesting that they contributed to community metabolism.	Nitrogen	47-48	glutamate dehydrogenase 1	Homo sapiens	70-73
24474781-3	2014	The crl gene has two overlapping promoters, a housekeeping, RpoD- (sigma(70)) dependent promoter, and an RpoN (sigma(54)) promoter that is strongly up-regulated under nitrogen limitation.	Nitrogen	167-175	interleukin 31 receptor A	Homo sapiens	4-7
24474781-6	2014	This elegant and economical mechanism, which allows a near-instantaneous reduction in Crl synthesis without the need for transacting regulatory factors, restrains the activity of RpoS to allow faster growth under nitrogen-limiting conditions.	Nitrogen	213-221	interleukin 31 receptor A	Homo sapiens	86-89
24315193-3	2014	C-11 was incorporated into (-)- and (+)-[(11)C]galanthamine by N-methylation of norgalanthamines with [(11)C]methyl triflate.	Nitrogen	63-64	polymerase (RNA) III (DNA directed) polypeptide K	Mus musculus	0-4
23836015-5	2014	ALD3 deletion strain overexpressing ARO9 and ARO10 both by episomal overexpression and by induction of the endogenous genes through overexpression of Aro80 transcription factor, produced 4.8 g/L 2-PE in a medium containing 10 g/L L-phenylalanine as a sole nitrogen source.	Nitrogen	256-264	aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	36-40
24701347-5	2014	In a wild type strain grown in the presence of leucine, when ammonium ion was the nitrogen source, Bap2p is the principal phenylalanine carrier.	Nitrogen	82-90	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	99-104
24000822-4	2014	The L-leucyl-L-tryptophan moiety and N-phosphoryl moiety of phosphoramidon was found in the S1 and S2 pockets of hECE-1 respectively.	Nitrogen	37-38	endothelin converting enzyme 1	Homo sapiens	113-119
23906857-1	2014	Rivers export increasing amounts of dissolved inorganic (DIN, DIP) and organic (DON, DOP) nitrogen and phosphorus to the Black Sea causing coastal eutrophication.	Nitrogen	90-98	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	127-130
23906857-6	2014	In these baselines, total N and P inputs to the Black Sea decrease between 2000 and 2050, but not for all rivers and nutrient forms.	Nitrogen	26-27	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	54-57
23906857-7	2014	Our results indicate that it is possible to reduce nutrient inputs to the sea further between 2000 and 2050 in particular for dissolved inorganic N and P and for many river basins, but not for all.	Nitrogen	146-147	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	74-77
23906857-8	2014	For scenarios assuming combined agricultural and sewage management dissolved inorganic N and P inputs to the Black Sea are reduced by up to two-thirds between 2000 and 2050 and dissolved organic N and P inputs by one-third.	Nitrogen	87-88	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	115-118
20213448-1	2010	The N-tosyl carbamates 4a-e, easily prepared starting from the Baylis-Hillman adducts 3a-e, underwent cyclization carried out with I(2)/NIS in the presence of NaH, to give the corresponding 2-oxo-1,3-oxazolidines 5a-e in good yield and total stereoselection when the substituent at C-5 is Ar.	Nitrogen	4-5	complement C5	Homo sapiens	282-285
25735931-4	2015	TUSC3 is localized to the endoplasmic reticulum in an oligosaccharyl tranferase complex responsible for the N-glycosylation of proteins.	Nitrogen	108-109	tumor suppressor candidate 3	Homo sapiens	0-5
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	39-40	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Canis lupus familiaris	69-75
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	39-40	vinculin	Canis lupus familiaris	262-270
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	63-64	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Canis lupus familiaris	69-75
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	63-64	vinculin	Canis lupus familiaris	262-270
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	63-64	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Canis lupus familiaris	69-75
20156436-4	2010	In MDCK cells, attenuation of cellular N-glycosylation with siRNA to DPAGT1, the first gene in the N-glycosylation pathway, reduced N-glycosylation of surface E-cadherin and resulted in increased recruitment of stabilizing proteins gamma-catenin, alpha-catenin, vinculin and PP2A to AJs.	Nitrogen	63-64	vinculin	Canis lupus familiaris	262-270
23682772-7	2013	We show that hGGT2 cDNAs are transcribed with a similar efficiency to hGGT1, and the expressed propeptides are N-glycosylated.	Nitrogen	21-22	gamma-glutamyltransferase 2, pseudogene	Homo sapiens	13-18
24133213-7	2013	HS disaccharide analysis showed that loss of Hsepi resulted in a significant impairment of 2-O-sulfation and induced compensatory increases in N- and 6-O-sulfation.	Nitrogen	143-144	Heparan sulfate C5-epimerase	Drosophila melanogaster	45-50
24194549-4	2013	The four surface mutations identified (R39P, L130S, E132A, P334L) map exclusively to the predicted syntaxin and soluble N-ethylmaleimide-sensitive factor accessory protein receptor binding sites of Munc18-2.	Nitrogen	120-121	syntaxin binding protein 2	Homo sapiens	198-206
24055074-1	2013	We have investigated the binding characteristics of a potent member of the bis-ortho-substituted five-membered nitrogen heterocycle class of ALK-5 kinase inhibitors with lysates of cultured HEK-293 cells to identify protein binding partners of potential biological significance.	Nitrogen	111-119	transforming growth factor beta receptor 1	Homo sapiens	141-146
24055074-7	2013	These observations warrant examination of bis-ortho-substituted five-membered nitrogen heterocycles as dual ALK-5/HSP-70 inhibitors for anti-cancer drug development.	Nitrogen	78-86	transforming growth factor beta receptor 1	Homo sapiens	108-113
20406859-11	2010	In conclusion, these data show that overall N-acetylation capacity of keratinocytes and consequently detoxification capacities of human skin is modulated by the presence of NAT1 substrates and endogenously by the cell proliferation status of keratinocytes.	Nitrogen	44-45	N-acetyltransferase 1	Homo sapiens	173-177
20483614-2	2010	Formation of CYP-mediated oxidative reactive metabolites previously observed in a related N(3)-phenylpyrazinone structure was minimized by incorporation of the additional ring nitrogen found in the triazinones.	Nitrogen	176-184	peptidylprolyl isomerase G	Homo sapiens	13-16
34801807-3	2022	As transducer, nitrogen doped carbon dots BSA (N-CD/BSA) nanocomposite electrodeposited on pencil graphite electrode was used to covalently immobilize AChE.	Nitrogen	15-23	acetylcholinesterase	Apis mellifera	151-155
20368337-0	2010	N-linked glycosylation of protease-activated receptor-1 second extracellular loop: a critical determinant for ligand-induced receptor activation and internalization.	Nitrogen	0-1	coagulation factor II (thrombin) receptor	Mus musculus	26-55
20368337-2	2010	To study the effect of N-linked glycosylation in the regulation of PAR1 signaling and trafficking, we generated mutants in which the critical asparagines of the consensus sites were mutated.	Nitrogen	23-24	coagulation factor II (thrombin) receptor	Mus musculus	67-71
20368337-3	2010	Here, we report that both the PAR1 N terminus and ECL2 serve as sites for N-linked glycosylation but have different functions in the regulation of receptor signaling and trafficking.	Nitrogen	35-36	coagulation factor II (thrombin) receptor	Mus musculus	30-34
20368337-4	2010	N-Linked glycosylation of the PAR1 N terminus is important for transport to the cell surface, whereas the PAR1 mutant lacking glycosylation at ECL2 (NA ECL2) trafficked to the cell surface like the wild-type receptor.	Nitrogen	0-1	coagulation factor II (thrombin) receptor	Mus musculus	30-34
20368337-4	2010	N-Linked glycosylation of the PAR1 N terminus is important for transport to the cell surface, whereas the PAR1 mutant lacking glycosylation at ECL2 (NA ECL2) trafficked to the cell surface like the wild-type receptor.	Nitrogen	0-1	coagulation factor II (thrombin) receptor	Mus musculus	106-110
20368337-4	2010	N-Linked glycosylation of the PAR1 N terminus is important for transport to the cell surface, whereas the PAR1 mutant lacking glycosylation at ECL2 (NA ECL2) trafficked to the cell surface like the wild-type receptor.	Nitrogen	0-1	epistatic circling C C57L/J 2	Mus musculus	152-156
20368337-9	2010	Thus, N-linked glycosylation of the PAR1 extracellular surface likely influences ligand docking interactions and the stability of the active receptor conformation.	Nitrogen	6-7	coagulation factor II (thrombin) receptor	Mus musculus	36-40
20368337-10	2010	Together, these studies strongly suggest that N-linked glycosylation of PAR1 at the N terminus versus the surface of ECL2 serves distinct functions critical for proper regulation of receptor trafficking and the fidelity of thrombin signaling.	Nitrogen	46-47	coagulation factor II (thrombin) receptor	Mus musculus	72-76
20378536-2	2010	TorC1 and intracellular nitrogen levels regulate the localization of Gln3 and Gat1, the activators of nitrogen catabolite repression (NCR)-sensitive genes whose products are required to utilize poor nitrogen sources.	Nitrogen	24-32	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	69-73
24180234-8	2013	CONCLUSIONS: AtPAP2 overexpression resulted in a widespread reprogramming of the transcriptome in the transgenic plants, which is characterized by changes in the carbon, nitrogen, potassium, and iron metabolism.	Nitrogen	170-178	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	13-19
23995080-0	2013	Nitrogen-enriched carbon electrodes in electrochemical capacitors: investigating accessible porosity using CM-SANS.	Nitrogen	0-8	USH1 protein network component sans	Homo sapiens	110-114
20378536-2	2010	TorC1 and intracellular nitrogen levels regulate the localization of Gln3 and Gat1, the activators of nitrogen catabolite repression (NCR)-sensitive genes whose products are required to utilize poor nitrogen sources.	Nitrogen	102-110	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	69-73
34826585-1	2022	OBJECTIVE: SNAP-25 is one of the key proteins involved in formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes that are at the core of hormonal secretion and synaptic transmission.	Nitrogen	79-80	vesicle transport through interaction with t-SNAREs 1B	Mus musculus	142-147
20378536-4	2010	During nitrogen limitation or Rap treatment, Gln3 and Gat1 are nuclear, and transcription is derepressed.	Nitrogen	7-15	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	45-49
20378536-8	2010	Gln3 localization predominantly responds to intracellular nitrogen levels, as reflected by its stronger NCR-sensitivity, weaker response to Rap treatment, and strong response to methionine sulfoximine (Msx, a glutamine synthetase inhibitor).	Nitrogen	58-66	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
23875773-5	2013	To explore this, we have utilized a range of spectroscopic techniques to show that NKB, but not substance P, can bind Cu(II) in an unusual [Cu(II)(NKB)2] neutral complex that utilizes two N-terminal amine and two imidazole nitrogen ligands (from each molecule of NKB) and the binding substantially alters the structure of the peptide.	Nitrogen	223-231	tachykinin precursor 3	Homo sapiens	83-86
23836288-6	2013	Analyses of N-glycosylation in agl-1(RNAi) animals by western blotting and mass spectrometry showed reduction of paucimannose and complex-type glycans and dramatic increase of glucosylated oligomannose glycans.	Nitrogen	12-13	4-alpha-glucanotransferase	Caenorhabditis elegans	31-36
34595702-4	2022	Total nitrogen (TN) was selected as the variable to calculate the uncertainty interval, and sensitive positions greatly affected by roughness as well as the appropriate range of roughness were explored by means of regional sensitive analysis (RSA).	Nitrogen	6-14	C-type lectin domain family 3 member B	Homo sapiens	16-18
24053168-1	2013	BACKGROUND: Glutamine Synthetase (GS, EC 6.3.1.2) is a central enzyme in nitrogen metabolism, and a key component of nitrogen use efficiency (NUE) and plant yield and thus it is extremely important to understand how it is regulated in plants.	Nitrogen	73-81	LOC11405318	Medicago truncatula	12-32
24053168-1	2013	BACKGROUND: Glutamine Synthetase (GS, EC 6.3.1.2) is a central enzyme in nitrogen metabolism, and a key component of nitrogen use efficiency (NUE) and plant yield and thus it is extremely important to understand how it is regulated in plants.	Nitrogen	117-125	LOC11405318	Medicago truncatula	12-32
24065976-4	2013	We have recently shown that the key nitrogen assimilatory enzyme glutamine synthetase (GS) is a molecular target of NO in root nodules of Medicago truncatula, being post-translationally regulated by tyrosine nitration in relation to nitrogen fixation.	Nitrogen	36-44	LOC11405318	Medicago truncatula	65-85
24065976-4	2013	We have recently shown that the key nitrogen assimilatory enzyme glutamine synthetase (GS) is a molecular target of NO in root nodules of Medicago truncatula, being post-translationally regulated by tyrosine nitration in relation to nitrogen fixation.	Nitrogen	233-241	LOC11405318	Medicago truncatula	65-85
20230508-1	2010	A soybean homolog of the tomato FW2.2 gene, here named GmFWL1 (Glycine max FW2.2-like 1), was found to respond strongly to inoculation with the nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum.	Nitrogen	144-152	protein fruit weight 2.2	Solanum lycopersicum	32-37
20230508-1	2010	A soybean homolog of the tomato FW2.2 gene, here named GmFWL1 (Glycine max FW2.2-like 1), was found to respond strongly to inoculation with the nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum.	Nitrogen	144-152	protein fruit weight 2.2	Solanum lycopersicum	75-80
20489023-4	2010	Notably, the cell cycle phosphatase Cdc14 associated with multiple kinases that revealed roles for Cdc14 in mitogen-activated protein kinase signaling, the DNA damage response, and metabolism, whereas interactions of the target of rapamycin complex 1 (TORC1) uncovered new effector kinases in nitrogen and carbon metabolism.	Nitrogen	293-301	phosphoprotein phosphatase CDC14	Saccharomyces cerevisiae S288C	36-41
20228058-6	2010	Pun1p abundance is doubled under conditions of nitrogen stress, and deletion of PUN1 abolishes filamentous growth in haploids and diploids; pun1Delta mutants are noninvasive, lack surface-spread filamentation, grow slowly, and exhibit impaired cell adhesion.	Nitrogen	47-55	Pun1p	Saccharomyces cerevisiae S288C	0-5
20228058-7	2010	Conversely, overexpression of PUN1 results in exaggerated cell elongation under conditions of nitrogen stress.	Nitrogen	94-102	Pun1p	Saccharomyces cerevisiae S288C	30-34
20228058-8	2010	PUN1 contributes to yeast nitrogen signaling, as pun1Delta mutants misregulate amino acid biosynthetic genes during nitrogen stress.	Nitrogen	26-34	Pun1p	Saccharomyces cerevisiae S288C	0-4
20228058-8	2010	PUN1 contributes to yeast nitrogen signaling, as pun1Delta mutants misregulate amino acid biosynthetic genes during nitrogen stress.	Nitrogen	116-124	Pun1p	Saccharomyces cerevisiae S288C	0-4
23845566-0	2013	Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin.	Nitrogen	31-39	transformation related protein 53, pseudogene	Mus musculus	13-16
34931842-4	2022	The ate complexes with the lithium atoms connected to the 3d metal atoms manganese, iron, or cobalt via mu2 nitrogen bridges reveal strong 7Li NMR paramagnetic shifts of about -75, 125, and 171 ppm, respectively, whereas the shifts for the lithium ions coordinated by the 15-crown-5 ether are close to zero.	Nitrogen	108-116	adaptor related protein complex 1 subunit mu 2	Homo sapiens	104-107
24039956-3	2013	Additionally, the C. parasitica Prodh and P5Cdh genes were able to complement the Saccharomyces cerevisiae put1 and put2 null mutants, respectively, to allow these proline auxotrophic yeast mutants to grow on media with proline as the sole source of nitrogen.	Nitrogen	250-258	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	116-120
20133892-0	2010	Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.	Nitrogen	25-26	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	14-21
20133892-1	2010	The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes.	Nitrogen	64-65	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	18-56
34346349-0	2022	Trends of the response-relationship between net anthropogenic nitrogen and phosphorus inputs (NANI/NAPI) and TN/TP export fluxes in Raohe basin, China.	Nitrogen	62-70	C-type lectin domain family 3 member B	Homo sapiens	109-111
20219979-5	2010	GLIPR1L1 is posttranslationally modified by N-linked glycosylation during spermatogenesis and ultimately becomes localized to the connecting piece of elongated spermatids and sperm.	Nitrogen	44-45	GLIPR1 like 1	Homo sapiens	0-8
23942187-5	2013	Significantly, genes coding for protein O-mannosyltransferase 2 (Pmt2p), which is responsible for the addition of the first mannosyl residue of O-linked carbohydrates, and for Eos1p, an enzyme involved in N-linked glycosylation of proteins, showed resistance to PAF26 and defects in CW integrity.	Nitrogen	205-206	Eos1p	Saccharomyces cerevisiae S288C	176-181
23722556-1	2013	In this theoretical work, a new idea about cooperativity in intermolecular clusters of CnHm   HCN   HW stabilized by hydrogen bonds composed by lone-electron pairs (nitrogen) and pi clouds (C = C and C   C) as proton acceptors is developed.	Nitrogen	165-173	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	94-97
20164234-4	2010	Our results showed that two potential N-linked glycosylation (PNLG) sites in the V2 and C2 regions of Env gp120 played an important role in regulating the susceptibility of CRF01_AE Env to b12.	Nitrogen	38-39	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	106-111
34346349-2	2022	Hence it is pivotal to clarify the response relationship between riverine TN/TP export and anthropogenic N/P inputs to provide strategies guidance in N/P management.	Nitrogen	105-106	C-type lectin domain family 3 member B	Homo sapiens	74-76
23742080-10	2013	Cycloheximide treatment experiments revealed that S185 degrades faster than T185 TMEM106B, potentially due to differences in N-glycosylation at residue N183.	Nitrogen	125-126	transmembrane protein 106B	Homo sapiens	81-89
34346349-2	2022	Hence it is pivotal to clarify the response relationship between riverine TN/TP export and anthropogenic N/P inputs to provide strategies guidance in N/P management.	Nitrogen	150-151	C-type lectin domain family 3 member B	Homo sapiens	74-76
34346349-3	2022	Based on the variation of net anthropogenic N and P inputs (NANI/NAPI) in the Raohe basin from 1990 to 2018, we constructed the response relationship between NANI/NAPI and total nitrogen and phosphorus (TN/TP) export fluxes in the riverine, which successfully predicted N and P export at the basin scale management.	Nitrogen	44-45	C-type lectin domain family 3 member B	Homo sapiens	203-205
20629321-6	2010	The expression of nephrin and the number of podocyte were negatively correlated with the 24-hour urine protein, blood urea nitrogen and serum creatinine; while the expression of VEGF was positively correlated with the 24-hour urine protein, blood urea nitrogen and serum creatinine.	Nitrogen	123-131	NPHS1 adhesion molecule, nephrin	Rattus norvegicus	18-25
23833276-9	2013	NLRP3(-/-) mice with ischemic AKI had significantly lower blood urea nitrogen, serum creatinine, and acute tubular necrosis and apoptosis scores than the wild-type controls.	Nitrogen	69-77	NLR family, pyrin domain containing 3	Mus musculus	0-5
20629321-6	2010	The expression of nephrin and the number of podocyte were negatively correlated with the 24-hour urine protein, blood urea nitrogen and serum creatinine; while the expression of VEGF was positively correlated with the 24-hour urine protein, blood urea nitrogen and serum creatinine.	Nitrogen	252-260	vascular endothelial growth factor A	Rattus norvegicus	178-182
34346349-3	2022	Based on the variation of net anthropogenic N and P inputs (NANI/NAPI) in the Raohe basin from 1990 to 2018, we constructed the response relationship between NANI/NAPI and total nitrogen and phosphorus (TN/TP) export fluxes in the riverine, which successfully predicted N and P export at the basin scale management.	Nitrogen	178-186	C-type lectin domain family 3 member B	Homo sapiens	203-205
19961832-9	2010	EPO resulted in less severe tissue injury and ameliorated the elevation in creatinine and urea nitrogen levels 24h after reperfusion.	Nitrogen	95-103	erythropoietin	Rattus norvegicus	0-3
20222671-3	2010	An N(C=S)S-S motif was found to be required, based on selective activity in BCA2-expressing breast cancer cell lines and against recombinant BCA2 protein.	Nitrogen	3-4	ring finger protein 115	Homo sapiens	76-80
23986249-4	2013	The GAR-3 N-terminal extracellular domain is necessary and sufficient for this asymmetric distribution, and mutation of a predicted N-linked glycosylation site within the N-terminus disrupts GAR-3-GFP localization.	Nitrogen	10-11	Muscarinic acetylcholine receptor gar-3	Caenorhabditis elegans	4-9
23986249-4	2013	The GAR-3 N-terminal extracellular domain is necessary and sufficient for this asymmetric distribution, and mutation of a predicted N-linked glycosylation site within the N-terminus disrupts GAR-3-GFP localization.	Nitrogen	10-11	Muscarinic acetylcholine receptor gar-3	Caenorhabditis elegans	191-196
20222671-3	2010	An N(C=S)S-S motif was found to be required, based on selective activity in BCA2-expressing breast cancer cell lines and against recombinant BCA2 protein.	Nitrogen	3-4	ring finger protein 115	Homo sapiens	141-145
34346349-3	2022	Based on the variation of net anthropogenic N and P inputs (NANI/NAPI) in the Raohe basin from 1990 to 2018, we constructed the response relationship between NANI/NAPI and total nitrogen and phosphorus (TN/TP) export fluxes in the riverine, which successfully predicted N and P export at the basin scale management.	Nitrogen	270-271	C-type lectin domain family 3 member B	Homo sapiens	203-205
23621281-6	2013	However, when N-replete plants were fed via the roots with sucrose, expression of specific OPPP and N assimilation genes in roots increased in the wild type but not in pgl3-1.	Nitrogen	14-15	NagB/RpiA/CoA transferase-like superfamily protein	Arabidopsis thaliana	168-172
34346349-4	2022	We found N export ratio (ratio of TN export to NANI) increased with slight fluctuation and was mainly affected by the combined effects of Nfer (fertilizer N inputs) and Ndep (atmospheric N deposition) etc., while the decrease of P export ratio (ratio of TP export to NAPI) was mainly due to intensive retention effect of the soil and sediment induced by anthropogenic influence to P transportation process.	Nitrogen	9-10	C-type lectin domain family 3 member B	Homo sapiens	34-36
34346349-4	2022	We found N export ratio (ratio of TN export to NANI) increased with slight fluctuation and was mainly affected by the combined effects of Nfer (fertilizer N inputs) and Ndep (atmospheric N deposition) etc., while the decrease of P export ratio (ratio of TP export to NAPI) was mainly due to intensive retention effect of the soil and sediment induced by anthropogenic influence to P transportation process.	Nitrogen	155-156	C-type lectin domain family 3 member B	Homo sapiens	34-36
20007348-10	2010	In experimental models of renal IRI, deficiency in clusterin expression worsened the injury, as indicated by a significant increase in renal tissue damage with higher levels of serum creatinine and blood urea nitrogen and by a poorer recovery from the injury in clusterin-deficient mice compared with wild-type mice.	Nitrogen	209-217	clusterin	Mus musculus	51-60
34346349-4	2022	We found N export ratio (ratio of TN export to NANI) increased with slight fluctuation and was mainly affected by the combined effects of Nfer (fertilizer N inputs) and Ndep (atmospheric N deposition) etc., while the decrease of P export ratio (ratio of TP export to NAPI) was mainly due to intensive retention effect of the soil and sediment induced by anthropogenic influence to P transportation process.	Nitrogen	187-188	C-type lectin domain family 3 member B	Homo sapiens	34-36
23766555-6	2013	Thus, Co2+ ion is coordinated in pseudo-tetrahedral geometry by four nitrogen atoms of adenine rings of two NAD+ molecules.	Nitrogen	69-77	complement C2	Homo sapiens	6-9
34606973-3	2022	Here, a global lake dataset (annual average data from 831 lakes) demonstrates that total nitrogen (TN): total phosphorous (TP) ratios declined significantly as lakes become more eutrophic.	Nitrogen	89-97	C-type lectin domain family 3 member B	Homo sapiens	99-101
23611809-10	2013	These findings suggest that UGT2B10 plays a major role in the N-glucuronidation of these drugs at therapeutic concentrations.	Nitrogen	62-63	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	28-35
19719386-1	2010	Signaling cascades initiated or regulated by calcium (Ca(2+)), reactive oxygen (ROS), and nitrogen (RNS) species are essential to diverse physiological and pathological processes in vascular smooth muscle.	Nitrogen	90-98	FAM20C golgi associated secretory pathway kinase	Homo sapiens	100-103
23668542-8	2013	The relevance of N-glycosylation in A1AT for the circulatory serum half-life was demonstrated in CD1 mice.	Nitrogen	17-18	CD1 antigen complex	Mus musculus	97-100
34341919-1	2022	A new multi-point inflow pre-anoxic/oxic/anaerobic/anoxic/oxic (A1/O2/A3/A4/O5) sludge-membrane coupling process and pilot plant were developed and designed to solve the problem of nitrogen and phosphorus removal of low carbon and nitrogen (C/N) ratio domestic sewage in southern China.	Nitrogen	243-244	immunoglobulin kappa variable 2D-36 (pseudogene)	Homo sapiens	70-78
34972198-5	2021	Loss of TSC1 and TSC2, that are negative regulators of TOR complex 1 (TORC1) in mammalian cells, resulted in altered nitrogen source-dependent growth of T. atroviride, reduced mycoparasitic overgrowth and, in the case of Deltatsc1, a diminished production of numerous secondary metabolites.	Nitrogen	117-125	CREB regulated transcription coactivator 1	Mus musculus	70-75
24073552-7	2013	There was a statistically significant correlation between higher ADAMTS13 activities and higher platelets count (p = 0.002), blood urea nitrogen (p = 0.000), and creatinine level (p = 0.000).	Nitrogen	136-144	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	65-73
34740685-5	2021	The motifs and sequence structures analysis showed that the significantly regulated N-glycosylation sites were concentrated within (NxT) motif, and 79.5% of them were located on the random coil that is always on the protein surface and flexible regions, which could facilitate protein glycosylated modification and enhance protein structural stability via reducing protein flexibility.	Nitrogen	84-85	nuclear transport factor 2 like export factor 1	Homo sapiens	132-135
23710622-5	2013	It contained a methylcyclohexyl derivative of 4-aminophenylalanine, and its cocrystal structure with gp120 revealed the cyclohexane ring buried within the gp120 hydrophobic core but able to assume multiple orientations in the binding pocket, and the aniline nitrogen potentially providing a focus for further improvement.	Nitrogen	258-266	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	101-106
34767348-7	2021	More than 21 novel mass features with nitrogen and sulfur functional groups were detected in the ESP component for the first time from helminths.	Nitrogen	38-46	protein tyrosine phosphatase receptor type V, pseudogene	Homo sapiens	97-100
23750228-1	2013	Receptor(-like) kinases with Lysin Motif (LysM) domains in their extracellular region play crucial roles during plant interactions with microorganisms; e.g. Arabidopsis thaliana CERK1 activates innate immunity upon perception of fungal chitin/chitooligosaccharides, whereas Medicago truncatula NFP and LYK3 mediate signalling upon perception of bacterial lipo-chitooligosaccharides, termed Nod factors, during the establishment of mutualism with nitrogen-fixing rhizobia.	Nitrogen	446-454	chitin elicitor receptor kinase 1	Arabidopsis thaliana	178-183
23297157-6	2013	In this study, capillary gel electrophoresis with laser-induced fluorescence detection (CGE-LIF) based glycoanalysis (N-glycan fingerprinting) was used to determine the impact of cultivation conditions on the HA N-glycosylation pattern of Madin-Darby canine kidney (MDCK) cell-derived influenza virus A PR/8/34 (H1N1).	Nitrogen	118-119	LIF interleukin 6 family cytokine	Canis lupus familiaris	92-95
34926888-0	2021	EDA-NOCV Calculation for Efficient N2 Binding to the Reduced Ni3S8 Complex: Estimation of Ni-N2 Intrinsic Interaction Energies.	Nitrogen	35-37	ectodysplasin A	Homo sapiens	0-3
23517290-2	2013	Rsp5 triggers the ubiquitination-dependent endocytosis of the general amino acid permease Gap1 in response to a good nitrogen source.	Nitrogen	117-125	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	0-4
34839261-9	2021	FINDINGS: The receptor binding domain and three distinct SARS-CoV-2 surface N-glycosylation sites among 57,311 spike proteins retrieved from the NCBI-Virus-database are highly evolutionarily conserved (99.67%) and are involved in ACE2 interaction.	Nitrogen	76-77	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	111-116
23675534-7	2013	We found that the number of Treg cells and the levels of the Treg cell-related transcription factor (Foxp3) and cytokines (IL-10) in the zymosan-treated group significantly decreased on day 1 and day 2 and significantly increased on day 5 compared with the NS-treated group.	Nitrogen	257-259	forkhead box P3	Mus musculus	101-106
34839261-9	2021	FINDINGS: The receptor binding domain and three distinct SARS-CoV-2 surface N-glycosylation sites among 57,311 spike proteins retrieved from the NCBI-Virus-database are highly evolutionarily conserved (99.67%) and are involved in ACE2 interaction.	Nitrogen	76-77	angiotensin converting enzyme 2	Homo sapiens	230-234
23667695-7	2013	The decrease in irisin levels was inversely correlated with the levels of blood urea nitrogen and creatinine.	Nitrogen	85-93	fibronectin type III domain containing 5	Homo sapiens	16-22
34884793-0	2021	Multimodal Spectroscopic Imaging of Pea Root Nodules to Assess the Nitrogen Fixation in the Presence of Biofertilizer Based on Nod-Factors.	Nitrogen	67-75	atrophin 1	Homo sapiens	127-130
23376777-3	2013	Site-directed mutagenesis was performed on the four putative extracellular N-linked glycosylation sites of KCC4 to determine the role of these sites in KCC4 half-life, cell surface expression, and transporter activity, as well as in KCC4-dependent tumor formation.	Nitrogen	75-76	solute carrier family 12, member 7	Mus musculus	107-111
23376777-4	2013	We showed that triple (N312/331/344/Q) and quadruple (N312/331/344/360/Q) mutations of N-linked glycosylation sites disrupt the N-linked glycosylation of KCC4, resulting in the accumulation of KCC4, predominantly in the endoplasmic reticulum (ER) and not at the cell surface.	Nitrogen	23-24	solute carrier family 12, member 7	Mus musculus	154-158
34884793-2	2021	These approaches were used to evaluate the effectiveness of nitrogen fixation by pea plants treated with biofertilizer preparations containing Nod factors.	Nitrogen	60-68	atrophin 1	Homo sapiens	143-146
23376777-4	2013	We showed that triple (N312/331/344/Q) and quadruple (N312/331/344/360/Q) mutations of N-linked glycosylation sites disrupt the N-linked glycosylation of KCC4, resulting in the accumulation of KCC4, predominantly in the endoplasmic reticulum (ER) and not at the cell surface.	Nitrogen	23-24	solute carrier family 12, member 7	Mus musculus	193-197
23376777-4	2013	We showed that triple (N312/331/344/Q) and quadruple (N312/331/344/360/Q) mutations of N-linked glycosylation sites disrupt the N-linked glycosylation of KCC4, resulting in the accumulation of KCC4, predominantly in the endoplasmic reticulum (ER) and not at the cell surface.	Nitrogen	54-55	solute carrier family 12, member 7	Mus musculus	154-158
34837246-7	2022	They contribute to the good development of nodulating white lupin plants when grown on N- and P-free media.	Nitrogen	87-88	5'-nucleotidase, cytosolic IIIA	Homo sapiens	60-65
23376777-4	2013	We showed that triple (N312/331/344/Q) and quadruple (N312/331/344/360/Q) mutations of N-linked glycosylation sites disrupt the N-linked glycosylation of KCC4, resulting in the accumulation of KCC4, predominantly in the endoplasmic reticulum (ER) and not at the cell surface.	Nitrogen	54-55	solute carrier family 12, member 7	Mus musculus	193-197
23376777-5	2013	Further investigation indicated that mutations of the central two (N331/344/Q) N-linked glycosylation sites inhibit the membrane trafficking of KCC4.	Nitrogen	67-68	solute carrier family 12, member 7	Mus musculus	144-148
34837246-8	2022	This study provides evidence that limited N and P availability in the nutrient solution can promote white lupin-Bradyrhizobium symbiosis, which is favorable for the sustainability of legume production.	Nitrogen	42-43	5'-nucleotidase, cytosolic IIIA	Homo sapiens	106-111
34841803-0	2021	(N-glycosylation modification of heat shock protein gp96 affects its immunological function).	Nitrogen	1-2	heat shock protein 90, beta (Grp94), member 1	Mus musculus	52-56
23263199-0	2013	N-glycosylations of human alpha1,3-fucosyltransferase IX are required for full enzyme activity.	Nitrogen	0-1	fucosyltransferase 9	Homo sapiens	35-56
34841803-1	2021	N-glycosylation modification, one of the most common protein post-translational modifications, occurs in heat shock protein gp96.	Nitrogen	0-1	heat shock protein 90, beta (Grp94), member 1	Mus musculus	124-128
34841803-2	2021	The purpose of this study is to investigate the effect of N-glycosylation modification on immunologic function of the recombinant gp96 using the mutant gp96 in N-glycosylation sites.	Nitrogen	58-59	heat shock protein 90, beta (Grp94), member 1	Mus musculus	130-134
23673980-2	2013	Eukaryotes have conserved N-myristoylation enzymes, involving one or two N-myristoyltransferases (NMT1 and NMT2), among which NMT1 is the major enzyme.	Nitrogen	26-27	NMT2	Arabidopsis thaliana	107-111
34841803-2	2021	The purpose of this study is to investigate the effect of N-glycosylation modification on immunologic function of the recombinant gp96 using the mutant gp96 in N-glycosylation sites.	Nitrogen	58-59	heat shock protein 90, beta (Grp94), member 1	Mus musculus	152-156
34841803-2	2021	The purpose of this study is to investigate the effect of N-glycosylation modification on immunologic function of the recombinant gp96 using the mutant gp96 in N-glycosylation sites.	Nitrogen	160-161	heat shock protein 90, beta (Grp94), member 1	Mus musculus	130-134
34841803-2	2021	The purpose of this study is to investigate the effect of N-glycosylation modification on immunologic function of the recombinant gp96 using the mutant gp96 in N-glycosylation sites.	Nitrogen	160-161	heat shock protein 90, beta (Grp94), member 1	Mus musculus	152-156
34841803-4	2021	To determine the effect of N-glycosylation on gp96 antigen presentation function, the IFN-gamma+ CD8+ T cells in gp96-immunized mice and secretion level of IFN-gamma were examined by flow cytometry and ELISA.	Nitrogen	27-28	heat shock protein 90, beta (Grp94), member 1	Mus musculus	46-50
23477529-0	2013	Nitrogen conversion in relation to NH3 and HCN during microwave pyrolysis of sewage sludge.	Nitrogen	0-8	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	43-46
34841803-6	2021	Finally, the effect of N-glycosylation on adjuvant function of gp96 for influenza vaccine was investigated in immunized mice.	Nitrogen	23-24	heat shock protein 90, beta (Grp94), member 1	Mus musculus	63-67
23477529-1	2013	The nitrogen conversions in relation to NH3 and HCN were investigated during microwave pyrolysis of sewage sludge.	Nitrogen	4-12	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	48-51
34841803-8	2021	Compared to the wild type recombinant gp96, mutations in N-glycosylation sites resulted in decreased antigen presentation ability and ATPase activity of gp96.	Nitrogen	57-58	heat shock protein 90, beta (Grp94), member 1	Mus musculus	38-42
23394863-4	2013	Replacement of the C(4)-oxo group with nitrogen- or sulfur- linked substituents gave decreased inhibitory activity for mPGES-1, and introduction of alkyl groups on the nitrogen atom at the N(1)-, the N(3)-, and the N(5)-positions resulted in even larger loss of inhibitory activity.	Nitrogen	39-47	prostaglandin E synthase	Mus musculus	119-126
34841803-8	2021	Compared to the wild type recombinant gp96, mutations in N-glycosylation sites resulted in decreased antigen presentation ability and ATPase activity of gp96.	Nitrogen	57-58	dynein, axonemal, heavy chain 8	Mus musculus	134-140
23210855-3	2013	In this study we focused on the potential activity of several clades of heterotrophic nitrogen-fixers identified by phylogenetic analysis of 44 non-Trichodesmium-related, nifH (encoding the Fe-subunit of nitrogenase) clones from the Arabian Sea.	Nitrogen	86-94	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	241-244
34841803-8	2021	Compared to the wild type recombinant gp96, mutations in N-glycosylation sites resulted in decreased antigen presentation ability and ATPase activity of gp96.	Nitrogen	57-58	heat shock protein 90, beta (Grp94), member 1	Mus musculus	153-157
23416356-7	2013	Together, these assays showed that the thioredoxin-like active sites of Ost3p and Ost6p could form transient mixed disulfide bonds with cysteines in a model substrate glycoprotein, consistent with the function of Ost3p and Ost6p in modulating N-glycosylation substrate selection by OTase in vivo.	Nitrogen	243-244	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	72-77
34841803-10	2021	These results demonstrate that N-glycosylation modification is involved in regulation of ATPase activity and antigen presentation function of gp96, thereby affecting its adjuvant function.	Nitrogen	31-32	dynein, axonemal, heavy chain 8	Mus musculus	89-95
23416356-7	2013	Together, these assays showed that the thioredoxin-like active sites of Ost3p and Ost6p could form transient mixed disulfide bonds with cysteines in a model substrate glycoprotein, consistent with the function of Ost3p and Ost6p in modulating N-glycosylation substrate selection by OTase in vivo.	Nitrogen	243-244	dolichyl-diphosphooligosaccharide--protein glycotransferase	Saccharomyces cerevisiae S288C	82-87
23416356-7	2013	Together, these assays showed that the thioredoxin-like active sites of Ost3p and Ost6p could form transient mixed disulfide bonds with cysteines in a model substrate glycoprotein, consistent with the function of Ost3p and Ost6p in modulating N-glycosylation substrate selection by OTase in vivo.	Nitrogen	243-244	dolichyl-diphosphooligosaccharide--protein glycotransferase OST3	Saccharomyces cerevisiae S288C	213-218
34841803-10	2021	These results demonstrate that N-glycosylation modification is involved in regulation of ATPase activity and antigen presentation function of gp96, thereby affecting its adjuvant function.	Nitrogen	31-32	heat shock protein 90, beta (Grp94), member 1	Mus musculus	142-146
23250914-3	2013	In this study, we show that expression of seipin N-glycosylation mutant N88S led to decreased triglyceride (TG) content in astrocytoma and motor neuron cell lines.	Nitrogen	49-50	BSCL2 lipid droplet biogenesis associated, seipin	Danio rerio	42-48
34869209-1	2021	The SARS-CoV-2 spike protein is heavily glycosylated, having 22 predicted N-glycosylation sites per monomer.	Nitrogen	74-75	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	15-20
23341449-8	2013	In addition, inserting non-conserved OCAM sequences into NCAM Ig5, including an "extra" N-glycosylation site, decreases or completely blocks NCAM polysialylation.	Nitrogen	57-58	neural cell adhesion molecule 1	Homo sapiens	141-145
20156104-4	2010	Potential N-linked glycosylation sites (PNLGs) were reasonably conserved among the 25 sequences: we found 15 highly conserved PNLGs on gp120 and 4 almost fully conserved PNLGs on gp41.	Nitrogen	10-11	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	135-146
34869209-10	2021	Comparison of the whole cell-derived WA1 and D614G spike proteins revealed that N-glycosites local to the mutation site appeared to be more readily detected, hinting that these sites are more exposed to glycosylation machinery.	Nitrogen	80-81	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	51-56
20462003-2	2010	Compared with CK and applying nitrogen fertilizer, the application of biogas liquid manure not only increased the aboveground biomass, leaf area index (LAI) and chlorophyll content, but also enhanced the activities of nitrate reductase (NR), glutamine synthetase (GS), and sucrose phosphate synthetase (SPS) in leaves and the sucrose synthetase (SS) in grains.	Nitrogen	30-38	nitrate reductase [NADH] 1	Zea mays	218-235
23235352-3	2013	The micelles could be broken easily and CdS NPs without a coating of surfactants could be obtained by bubbling N(2) at 65  C.	Nitrogen	111-115	CDP-diacylglycerol synthase 1	Homo sapiens	40-43
34800464-7	2022	The small variation of water chemistry (EC, DO and pH), nitrate concentration and dual nitrate isotope values in deep wells during sampling period suggested that newly supplied nitrogen in deep groundwater during rainfall events also comes from deep groundwater.	Nitrogen	177-185	phenylalanine hydroxylase	Homo sapiens	51-53
23431188-4	2013	In the current study, we addressed the physiological function of a poorly characterized N-recognin, 570-kDa UBR4, in mammalian development.	Nitrogen	88-89	ubiquitin protein ligase E3 component n-recognin 4	Homo sapiens	108-112
19900493-0	2010	Modification of N-glycosylation sites allows secretion of bacterial chondroitinase ABC from mammalian cells.	Nitrogen	16-17	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	68-82
19900493-3	2010	Here we show that such interference does indeed occur for chondroitinase ABC from the bacterium Proteus vulgaris, and can be overcome by eliminating potential N-glycosylation sites.	Nitrogen	159-160	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	58-72
34340182-4	2021	METHODS: In this study, land use regression models (LUR) were developed to predict the outdoor nitrogen dioxide (NO2) concentration in the study area of the Western Region Birth Cohort in Sao Paulo.	Nitrogen	95-103	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	188-191
19900493-5	2010	Directed mutagenesis of selected N-glycosylation sites allowed efficient secretion of active chondroitinase.	Nitrogen	33-34	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	93-107
23190030-3	2013	The beneficial effects on human health, many of phenolics have been described to their reactive oxygen (ROS) and nitrogen species (RNS) scavenging and antioxidant capacity.	Nitrogen	113-121	FAM20C golgi associated secretory pathway kinase	Homo sapiens	131-134
34747459-9	2021	When 2B11.3 was injected, CCR2-/- and CCR5-/-, but not CX3CR1-/-, mice exhibited reduced endocapillary hypercellularity, attenuated glomerular macrophage infiltration, and improved serum blood urea nitrogen (BUN) levels.	Nitrogen	198-206	chemokine (C-C motif) receptor 2	Mus musculus	26-30
23368840-1	2013	A one-pot cascade transformation of chalcones into beta-imidoketones has been developed, in which NBS provides both electrophilic bromine and nucleophilic nitrogen sources, and DBU functions as a nucleophilic reagent to activate NBS to be a more electrophilic bromine species and to further remove the bromine of alpha-bromoketones.	Nitrogen	155-163	nibrin	Homo sapiens	98-101
19800385-1	2010	Human IGFBP-3 contains three potential N-linked glycosylation sites.	Nitrogen	39-40	insulin like growth factor binding protein 3	Homo sapiens	6-13
19800385-8	2010	N-glycosylation of IGFBP-3 follows the N-glycosylation pattern of major serum proteins.	Nitrogen	0-1	insulin like growth factor binding protein 3	Homo sapiens	19-26
19800385-8	2010	N-glycosylation of IGFBP-3 follows the N-glycosylation pattern of major serum proteins.	Nitrogen	39-40	insulin like growth factor binding protein 3	Homo sapiens	19-26
19858196-8	2010	Kinetic results suggest that GDH1 facilitates regeneration of the form of BCATm that binds to E1 decarboxylase of the BCKDC, promotes metabolon formation, branched-chain amino acid oxidation, and cycling of nitrogen through glutamate.	Nitrogen	207-215	glutamate dehydrogenase 1	Homo sapiens	29-33
20308801-2	2010	In the nucleus tractus solitarius neurons, hypoxia with N(2) or NaCN decreased the amplitude of excitatory postsynaptic currents (EPSCs) similarly in wild type (WT) and PDGFR-beta gene-knockout (KO) mice.	Nitrogen	56-60	platelet derived growth factor receptor, beta polypeptide	Mus musculus	169-179
23088624-0	2013	N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.	Nitrogen	0-1	protein phosphatase, Mg2+/Mn2+ dependent 1B	Homo sapiens	65-70
23088624-3	2013	N-Myristoylation was also required for two other functions of PPM1A and PPM1B in cells.	Nitrogen	0-1	protein phosphatase, Mg2+/Mn2+ dependent 1B	Homo sapiens	72-77
23088624-6	2013	Taken together, the results of the present study suggest that N-myristoylation of PPM1A and PPM1B plays a key role in recognition of their physiological substrates in cells.	Nitrogen	62-63	protein phosphatase, Mg2+/Mn2+ dependent 1B	Homo sapiens	92-97
23005037-0	2013	Modulation of CD147-induced matrix metalloproteinase activity: role of CD147 N-glycosylation.	Nitrogen	77-78	basigin (Ok blood group)	Homo sapiens	71-76
34988176-0	2021	N-glycosylation of somatostatin receptor type 2 protects rats from acute pancreatitis.	Nitrogen	0-1	somatostatin receptor 2	Rattus norvegicus	19-47
19904223-8	2010	RESULTS: Among the 14 differentially expressed proteins after oxythiamine treatment, tissue inhibitor of metalloproteases-1 and cytokeratin-10 were identified as 2 newly synthesized secreted proteins caused by substantial N incorporation.	Nitrogen	222-223	keratin 10	Homo sapiens	128-142
34988176-3	2021	Somatostatin analogs preferentially bind to somatostatin receptor 2 (SSTR2), and this study aimed to investigate whether N-glycosylation affects SSTR2 stability, membrane trafficking, and signal transduction.	Nitrogen	121-122	somatostatin receptor 2	Rattus norvegicus	44-67
34988176-3	2021	Somatostatin analogs preferentially bind to somatostatin receptor 2 (SSTR2), and this study aimed to investigate whether N-glycosylation affects SSTR2 stability, membrane trafficking, and signal transduction.	Nitrogen	121-122	somatostatin receptor 2	Rattus norvegicus	69-74
19846557-0	2009	Regulation of homotypic cell-cell adhesion by branched N-glycosylation of N-cadherin extracellular EC2 and EC3 domains.	Nitrogen	55-56	transcription factor 15	Homo sapiens	99-102
34988176-3	2021	Somatostatin analogs preferentially bind to somatostatin receptor 2 (SSTR2), and this study aimed to investigate whether N-glycosylation affects SSTR2 stability, membrane trafficking, and signal transduction.	Nitrogen	121-122	somatostatin receptor 2	Rattus norvegicus	145-150
34988176-4	2021	Methods: Western blot analysis following PNGase F digestion was performed to confirm N-glycosylation of SSTR2 in rat pancreatic acinar AR42J cells.	Nitrogen	85-86	somatostatin receptor 2	Rattus norvegicus	104-109
34988176-7	2021	Proteasome inhibitor MG132 was employed to assess the stability of SSTR2, and overexpression of wild-type or N9Q-mutant SSTR2 was used to examine the role of N-glycosylation in SSTR2 signal transduction in vitro and its therapeutic effect on pancreatitis in rats.	Nitrogen	158-159	somatostatin receptor 2	Rattus norvegicus	177-182
34988176-8	2021	Results: SSTR2 protein in AR42J cells was N-glycosylated at the N9 residue.	Nitrogen	42-43	somatostatin receptor 2	Rattus norvegicus	9-14
34988176-13	2021	Conclusions: N-glycosylation of SSTR2 is essential for membrane localization, stability, and signal transduction of SSTR2 in pancreatic cells, playing a protective role in experimental acute pancreatitis.	Nitrogen	13-14	somatostatin receptor 2	Rattus norvegicus	32-37
34988176-13	2021	Conclusions: N-glycosylation of SSTR2 is essential for membrane localization, stability, and signal transduction of SSTR2 in pancreatic cells, playing a protective role in experimental acute pancreatitis.	Nitrogen	13-14	somatostatin receptor 2	Rattus norvegicus	116-121
19762344-0	2009	Inhibition of electron acceptance from ascorbate by the specific N-carbethoxylations of maize cytochrome b561: a common mechanism for the transmembrane electron transfer in cytochrome b561 protein family.	Nitrogen	65-66	cytochrome b561	Zea mays	94-109
19762344-0	2009	Inhibition of electron acceptance from ascorbate by the specific N-carbethoxylations of maize cytochrome b561: a common mechanism for the transmembrane electron transfer in cytochrome b561 protein family.	Nitrogen	65-66	cytochrome b561	Zea mays	173-188
34147984-1	2021	Denitrification in electroactive constructed wetland (EW) systems is constrained by the carbon source and the carbon/nitrogen (C/N) ratio (the COD/TN ratio).	Nitrogen	117-125	C-type lectin domain family 3 member B	Homo sapiens	147-149
34147984-1	2021	Denitrification in electroactive constructed wetland (EW) systems is constrained by the carbon source and the carbon/nitrogen (C/N) ratio (the COD/TN ratio).	Nitrogen	129-130	C-type lectin domain family 3 member B	Homo sapiens	147-149
34105076-8	2021	Furthermore, it was confirmed by linear regression that the ratios of DOC/TN, NH4+-N/TN, and DOC/NH4+-N were the determining indexes for evaluating the phytotoxicity and nutrition behavior of the PWs as liquid nitrogen fertilizers.	Nitrogen	210-218	C-type lectin domain family 3 member B	Homo sapiens	74-76
34105076-8	2021	Furthermore, it was confirmed by linear regression that the ratios of DOC/TN, NH4+-N/TN, and DOC/NH4+-N were the determining indexes for evaluating the phytotoxicity and nutrition behavior of the PWs as liquid nitrogen fertilizers.	Nitrogen	210-218	C-type lectin domain family 3 member B	Homo sapiens	85-87
34737629-1	2021	Background: We aimed to evaluate the prognostic ability of blood urea nitrogen (BUN) to serum albumin ratio (BAR) to predict in-hospital mortality in patients with lung cancer in the intensive care unit (ICU).	Nitrogen	70-78	bifunctional apoptosis regulator	Homo sapiens	109-112
34778038-1	2021	Ribophorin 1 (RPN1) is a major part of Oligosaccharyltransferase (OST) complex, which is vital for the N-linked glycosylation.	Nitrogen	103-104	ribophorin I	Homo sapiens	0-12
34778038-1	2021	Ribophorin 1 (RPN1) is a major part of Oligosaccharyltransferase (OST) complex, which is vital for the N-linked glycosylation.	Nitrogen	103-104	ribophorin I	Homo sapiens	14-18
34463382-3	2021	Herein, selective dual-defect engineering (i.e., introducing both N-doping and Se-vacancies) of a common MoSe2 electrocatalyst is used to manipulate the bidirectional Li2 S redox.	Nitrogen	66-67	ATP binding cassette subfamily A member 12	Homo sapiens	167-170
34091387-3	2021	We found a high N burden of 2-9 kg N ha-1 yr-1 over the Yellow Sea, East China Sea (ECS), and Sea of Japan.	Nitrogen	16-17	solute carrier family 9 member B1	Homo sapiens	35-46
34537173-1	2021	The mannosyltransferase Alg9 plays a vital role in N-linked protein glycosylation in Saccharomyces cerevisiae, but its function in most filamentous fungi is not clear.	Nitrogen	51-52	dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase	Saccharomyces cerevisiae S288C	24-28
34631661-7	2021	We identified 21 and 19 out of the 22 predicted N-glycosites of the SARS-CoV-2 S proteins produced in CHO and HEK, respectively.	Nitrogen	48-49	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	79-80
34414719-6	2021	However, the total phosphorus (TP) and total nitrogen (TN) load was relatively high, with 10 stations in the Hanjiang River basin showing averaged concentrations of 0.028-0.263 mg L-1 and 0.630-1.852 mg L-1, respectively, during 2014-2018.	Nitrogen	45-53	C-type lectin domain family 3 member B	Homo sapiens	55-57
34327998-8	2021	Comparisons of GADS for N-glycosylated sites on several proteins, especially the SARS-CoV-2 spike protein, demonstrate the potential reproducibility of GADS and their utility for comparing site-specific distributions.	Nitrogen	24-25	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	92-97
34410096-0	2021	Efficient Photocatalytic Reduction of CO2 to CO Using NiFe2O4@N/C/SnO2 Derived from FeNi Metal-Organic Framework.	Nitrogen	62-63	strawberry notch homolog 1	Homo sapiens	66-69
34466058-6	2021	The results showed that under the conditions of 225 kg/hm2 nitrogen application and 60%+40% nitrogen application rate, the yield of Jintai 182 was the highest compared with other treatment groups.	Nitrogen	59-67	cholinergic receptor muscarinic 2	Homo sapiens	55-58
23114624-2	2013	The 1:3 AgSCN : ER(3) complexes structurally defined (for PPh(3),AsPh(3) (diversely solvated)) take the form [(R(3)E)(3)AgX], the thiocyanate X = NCS being N-bound, thus [(Ph(3)E)Ag(NCS)].	Nitrogen	12-13	aspartate beta-hydroxylase	Homo sapiens	65-69
24648901-7	2013	No difference was found in the T/N ratio of PD-L1/beta actin mRNA levels among factors inlcuding gender, age, smoking status and pathological subtypes.	Nitrogen	0-1	CD274 molecule	Homo sapiens	44-49
34466058-6	2021	The results showed that under the conditions of 225 kg/hm2 nitrogen application and 60%+40% nitrogen application rate, the yield of Jintai 182 was the highest compared with other treatment groups.	Nitrogen	92-100	cholinergic receptor muscarinic 2	Homo sapiens	55-58
24648901-8	2013	The T/N ratio of PD-L1/beta actin mRNA levels was markedly higher in pathological T4 cases (15.811+-36.883) compared to T1 cases (3.492+-8.494, P=0.0235).	Nitrogen	6-7	CD274 molecule	Homo sapiens	17-22
34358905-1	2021	Excessive total nitrogen (TN) in the aqueous environment causes a notable negative impact on agriculture, human health, and the economy on a global scale.	Nitrogen	16-24	C-type lectin domain family 3 member B	Homo sapiens	26-28
23984327-6	2013	These substances were inactivated by cytochrome P450 2D6 through N-demethylation and aromatic hydroxylation (MPTP) and aromatic hydroxylation (2-methyltetrahydro-beta-carboline).	Nitrogen	65-66	cytochrome P450 2D6	Homo sapiens	37-56
23065485-10	2013	Specifically, our results confirm the effect of PYROXD2 polymorphisms on trimethylamine metabolism and suggest that a previously reported association of N-acetylated compounds with the ALMS1/NAT8 locus is driven by SNPs in the ALMS1 gene.	Nitrogen	153-154	pyridine nucleotide-disulphide oxidoreductase domain 2	Homo sapiens	48-55
34358905-6	2021	It contains a TN reaction chamber for nitrogen digestion and reduction, and an optical measurement chamber for colorimetric determination of total nitrite.	Nitrogen	38-46	C-type lectin domain family 3 member B	Homo sapiens	14-16
23065485-10	2013	Specifically, our results confirm the effect of PYROXD2 polymorphisms on trimethylamine metabolism and suggest that a previously reported association of N-acetylated compounds with the ALMS1/NAT8 locus is driven by SNPs in the ALMS1 gene.	Nitrogen	153-154	ALMS1 centrosome and basal body associated protein	Homo sapiens	185-190
23065485-10	2013	Specifically, our results confirm the effect of PYROXD2 polymorphisms on trimethylamine metabolism and suggest that a previously reported association of N-acetylated compounds with the ALMS1/NAT8 locus is driven by SNPs in the ALMS1 gene.	Nitrogen	153-154	ALMS1 centrosome and basal body associated protein	Homo sapiens	227-232
34578530-0	2021	Preparation of Metal Nitride Particles Using Arc Discharge in Liquid Nitrogen.	Nitrogen	69-77	activity regulated cytoskeleton associated protein	Homo sapiens	45-48
21837554-1	2013	Parallel acquisition NMR spectroscopy (PANSY) is used to detect simultaneously signals from up to four nuclear species, such as H-1, H-2, C-13, N-15, F-19 and P-31.	Nitrogen	21-22	H1.5 linker histone, cluster member	Homo sapiens	128-131
19808681-0	2009	Triple N-glycosylation in the long S5-P loop regulates the activation and trafficking of the Kv12.2 potassium channel.	Nitrogen	7-8	potassium voltage-gated channel subfamily H member 3	Homo sapiens	93-99
19808681-2	2009	Kv12.2 features the longest S5-P loop among all known mammalian Kv channels with the most N-linked glycosylation sites (three sites).	Nitrogen	90-91	potassium voltage-gated channel subfamily H member 3	Homo sapiens	0-6
19808681-4	2009	Because glycosylation plays important roles in the folding, trafficking, and function of various Kv channels, we focused on the N-glycosylation of Kv12.2.	Nitrogen	128-129	potassium voltage-gated channel subfamily H member 3	Homo sapiens	147-153
19808681-5	2009	We show that Kv12.2 is N-glycosylated in Chinese hamster ovary (CHO) cells and in cultured neurons as well as in the mouse brain.	Nitrogen	23-24	potassium voltage-gated channel subfamily H member 3	Homo sapiens	13-19
19808681-6	2009	As an effect of N-glycosylation on the function of Kv12.2, we demonstrate that removal of sugar chains causes a depolarizing shift in the steady-state activation without a significant reduction in current amplitude.	Nitrogen	16-17	potassium voltage-gated channel subfamily H member 3	Homo sapiens	51-57
34456583-0	2021	Blood Urea Nitrogen to Serum Albumin Ratio (BAR) Predicts Critical Illness in Patients with Coronavirus Disease 2019 (COVID-19).	Nitrogen	11-19	bifunctional apoptosis regulator	Homo sapiens	44-47
19706343-2	2009	beta2GPI is N-glycosylated at several asparagine residues and the glycan moiety conjugated to residue 143 has been proposed to interact with the Gly40-Arg43 motif of beta2GPI.	Nitrogen	12-13	apolipoprotein H	Homo sapiens	0-8
19706343-2	2009	beta2GPI is N-glycosylated at several asparagine residues and the glycan moiety conjugated to residue 143 has been proposed to interact with the Gly40-Arg43 motif of beta2GPI.	Nitrogen	12-13	apolipoprotein H	Homo sapiens	166-174
23787303-1	2013	ANITA  Mox is a new one-stage deammonification Moving-Bed Biofilm Reactor (MBBR) developed for partial nitrification to nitrite and autotrophic N-removal from N-rich effluents.	Nitrogen	1-2	monooxygenase DBH like 1	Homo sapiens	7-10
23787303-1	2013	ANITA  Mox is a new one-stage deammonification Moving-Bed Biofilm Reactor (MBBR) developed for partial nitrification to nitrite and autotrophic N-removal from N-rich effluents.	Nitrogen	144-145	monooxygenase DBH like 1	Homo sapiens	7-10
34456583-1	2021	Purpose: We sought to explore the prognostic value of blood urea nitrogen (BUN) to serum albumin ratio (BAR) and further develop a prediction model for critical illness in COVID-19 patients.	Nitrogen	65-73	bifunctional apoptosis regulator	Homo sapiens	104-107
34353900-6	2021	RNF186, along with its intact E3-ubiquitin ligase activity, was required for optimal PRR-induced antimicrobial reactive oxygen species, reactive nitrogen species, and autophagy pathways and intracellular bacterial clearance in human macrophages and for bacterial clearance in intestinal myeloid cells.	Nitrogen	145-153	ring finger protein 186	Homo sapiens	0-6
23076206-1	2012	Direct C-2 amidation of indoles was reported using sulfonyl azides as the amino source to release N(2) as the single byproduct.	Nitrogen	98-102	complement C2	Homo sapiens	7-10
20183496-1	2009	The SPARC software program was validated for nitrogen-hydrogen acidity constant estimation of primary and secondary sulfonamides against a broad suite of substituted derivatives with experimental datasets in water and dimethylsulfoxide solvent systems and across a wide pK(a) range.	Nitrogen	45-53	secreted protein acidic and cysteine rich	Homo sapiens	4-9
34421960-5	2021	Our results suggest that high N availability (>100 kg N ha-1) could disadvantage the growth of ECM plants because of increased C costs associated with maintaining higher root N concentrations, while the insensitivity in SRR by AM plants to N fertilisation may be because AM fungi are more important for phosphorus (P) uptake.	Nitrogen	30-31	solute carrier family 9 member B1	Homo sapiens	54-60
19684018-2	2009	The extracellular 65-amino acid amino terminus of hCTR1 contains both N-linked (at Asn(15)) and O-linked (at Thr(27)) sites of glycosylation.	Nitrogen	70-71	solute carrier family 31 member 1	Homo sapiens	50-55
20502620-0	2009	N-glycosylation status of E-cadherin controls cytoskeletal dynamics through the organization of distinct beta-catenin- and gamma-catenin-containing AJs.	Nitrogen	0-1	catenin beta 1	Homo sapiens	105-117
20502620-2	2009	Specifically, our recent studies have provided evidence that the reduction of E-cadherin N-glycosylation promoted the recruitment of stabilizing components, vinculin and serine/threonine protein phosphatase 2A (PP2A), to adherens junctions (AJs) and enhanced the association of AJs with the actin cytoskeleton.	Nitrogen	89-90	protein phosphatase 2 phosphatase activator	Homo sapiens	211-215
20502620-8	2009	These studies provide the first mechanistic insights into how N-glycosylation of E-cadherin drives changes in AJ composition through the assembly of distinct beta-catenin- and gamma-catenin-containing scaffolds that impact the interaction with different cytoskeletal components.	Nitrogen	62-63	catenin beta 1	Homo sapiens	158-170
19753315-7	2009	The N-glycosylation status of CLRN1 was studied by using the N-glycosidase F (PNGase F) enzyme and western blotting.	Nitrogen	4-5	clarin 1	Homo sapiens	30-35
22671972-1	2012	Proteins are major targets of reactive oxygen and nitrogen species (ROS/RNS) and numerous post-translational, reversible or irreversible modifications have been characterized, which may lead to a change in the structure and/or function of the oxidized protein.	Nitrogen	50-58	FAM20C golgi associated secretory pathway kinase	Homo sapiens	72-75
23081989-2	2012	Tyrosine-nitrated proteins, a footprint of oxygen- and nitrogen-derived oxidants generated by cells of the immune system, are enriched in atheromatous lesions and in circulation of patients with coronary artery disease (CAD).	Nitrogen	55-63	aconitate decarboxylase 1	Homo sapiens	220-223
23136435-1	2012	Trans-soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes formed between the SNARE motifs of synaptobrevin II, SNAP-25, and syntaxin play an essential role in Ca(2+)-regulated exocytosis.	Nitrogen	14-15	synaptosomal-associated protein 25	Mus musculus	154-161
34421960-5	2021	Our results suggest that high N availability (>100 kg N ha-1) could disadvantage the growth of ECM plants because of increased C costs associated with maintaining higher root N concentrations, while the insensitivity in SRR by AM plants to N fertilisation may be because AM fungi are more important for phosphorus (P) uptake.	Nitrogen	175-176	solute carrier family 9 member B1	Homo sapiens	54-60
34254213-9	2021	Finally, exogenous administration of apelin normalized the serum level of creatinine and urea nitrogen and the urine levels of NGAL and Kim-1.	Nitrogen	94-102	apelin	Mus musculus	37-43
22956764-6	2012	Significantly, global N-linked glycosylation and LLO levels were reduced in pmm2 morphants.	Nitrogen	22-23	phosphomannomutase 2	Danio rerio	76-80
19663410-5	2009	Under vacuum the MP2, MP4, and CCSD(T) wave function methods predicted a broad anharmonic potential energy well or even a double-well for the amide nitrogen out of plane motion, which density functional methods failed to reproduce.	Nitrogen	148-156	tryptase pseudogene 1	Homo sapiens	17-20
34089296-9	2021	Therefore, we proposed that the ESCRT-III machinery mediates nitrogen starvation-induced macromitophagy by the interaction between Snf7 and Atg11 so that Snf7 is recruited to Atg32 marked MPs by the known Atg11-Atg32 interaction to seal them.	Nitrogen	61-69	ESCRT-III subunit protein SNF7	Saccharomyces cerevisiae S288C	131-135
22977256-5	2012	The N-glycosylation of GdA mediates the binding and therefore the activities of the molecule.	Nitrogen	4-5	progestagen associated endometrial protein	Homo sapiens	23-26
34259497-2	2021	The process leads to a clean nitrogen-terminated GaN surface that bonds well to the MoS2 film revealing a 2 x 2 reconstruction at the interface observed in low-energy electron diffraction (LEED).	Nitrogen	29-37	gigaxonin	Homo sapiens	49-52
22984264-0	2012	N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane.	Nitrogen	0-1	protein phosphatase 3 regulatory subunit B, alpha	Homo sapiens	37-50
22952022-2	2012	These findings have prompted further investigations on the organometallic analogues of the formula [(CN)(2)AlR], anticipating their utility as N,N-metalloligands for ZnR(2) units.	Nitrogen	102-103	growth factor, augmenter of liver regeneration	Homo sapiens	107-110
19541770-2	2009	Here, we used (15)N-(1)H HSQC and pulse field gradient (PFG) NMR spectroscopy to demonstrate that galectin-1 (gal-1) binds to the relatively large galactomannan Davanat, whose backbone is composed of beta1-4-linked d-mannopyranosyl units to which single d-galactopyranosyl residues are periodically attached via alpha1-6 linkage (weight-average MW of 59 kDa).	Nitrogen	18-19	galectin 1	Homo sapiens	98-108
19541770-2	2009	Here, we used (15)N-(1)H HSQC and pulse field gradient (PFG) NMR spectroscopy to demonstrate that galectin-1 (gal-1) binds to the relatively large galactomannan Davanat, whose backbone is composed of beta1-4-linked d-mannopyranosyl units to which single d-galactopyranosyl residues are periodically attached via alpha1-6 linkage (weight-average MW of 59 kDa).	Nitrogen	18-19	galectin 1	Homo sapiens	110-115
19534677-4	2009	The derived QSAR models demonstrated that the COX-2 selectivity over COX-1 is predominantly influenced by the central core -N=C- of the diaryl system.	Nitrogen	124-125	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	69-74
22952022-2	2012	These findings have prompted further investigations on the organometallic analogues of the formula [(CN)(2)AlR], anticipating their utility as N,N-metalloligands for ZnR(2) units.	Nitrogen	143-144	growth factor, augmenter of liver regeneration	Homo sapiens	107-110
34295263-6	2021	In brief, carbon and nitrogen redistribution to challenged tissues (muscle and lungs) for fuel replenishment and cell regeneration against abdominal adipose tissue seems to be the fundamental mechanism underlying the intensity-dependent fat loss effect of exercise.	Nitrogen	21-29	FAT atypical cadherin 1	Homo sapiens	237-240
22945294-1	2012	A versatile cascade of reactions, triggered by Rh(II)-catalyzed diazo decomposition followed by a vinylogous N-H insertion/Lewis acid catalyzed Mannich addition, that produces highly substituted 1,2,3,6-tetrahydropyridazines in up to 97 % ee with high yield and diastereocontrol has been developed.	Nitrogen	109-110	Rh blood group D antigen	Homo sapiens	47-52
19621239-2	2009	In response to nitrogen depletion, the MYB genes PAP1/PAP2 (production of anthocyanin pigment 1/2) and GL3 are strongly induced, and anthocyanin synthesis is activated in seedlings and rosette stage plants.	Nitrogen	15-23	phosphatidic acid phosphatase 1	Arabidopsis thaliana	49-53
19621239-2	2009	In response to nitrogen depletion, the MYB genes PAP1/PAP2 (production of anthocyanin pigment 1/2) and GL3 are strongly induced, and anthocyanin synthesis is activated in seedlings and rosette stage plants.	Nitrogen	15-23	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	54-58
21577535-1	2009	In the enanti-omerically pure title compound, C(11)H(19)N(3)O(3)S, the chain C-N-C(O)-O-C-C (from the asymmetric carbon to a methyl of the tert-butyl group) displays an extended conformation.	Nitrogen	56-57	telomerase reverse transcriptase	Homo sapiens	139-143
22245701-1	2012	BACKGROUND: Over the years, the N-glycosylation of both human and bovine lactoferrin (LF) has been studied extensively, however not all aspects have been studied in as much detail.	Nitrogen	8-9	lactotransferrin	Bos taurus	73-84
22245701-8	2012	CONCLUSIONS: Applying the approach to bovine LF has led to a more detailed N-glycome pattern, including LacdiNAc, alphaGal, and Neu5Gc epitopes, than was shown in previous studies.	Nitrogen	2-3	lactotransferrin	Bos taurus	45-47
22622494-7	2012	Combined mineralocorticoid receptor antagonism and aldosterone deficiency reduced blood urea nitrogen and restored nephrin immunoreactivity.	Nitrogen	93-101	nuclear receptor subfamily 3, group C, member 2	Mus musculus	9-35
19538945-8	2009	We tested whether VIP-induced arteriolar dilation was sensitive to inhibitors of cyclooxygenase (COX)-1 (SC-560, 1 mg/kg), COX-2 (NS-398, 1 mg/kg), indomethacin (5 mg/kg), and nitric oxide synthase (L-NAME, 15 mg/kg).	Nitrogen	130-132	vasoactive intestinal peptide	Sus scrofa	18-21
19647169-2	2009	Based on our previous studies, the most VAP-1-selective peptide (VAP-P1) was 1,4,7,10-tetraazacyclododecane-N",N"",N""",N-tetraacetic acid (DOTA)-conjugated, 68gallium (68Ga)-labeled (named [68Ga]DOTAVAP-P1) and evaluated preliminarily.	Nitrogen	115-119	amine oxidase, copper containing 3	Rattus norvegicus	40-45
34295263-7	2021	The magnitude of lipolysis (fatty acid release from adipocytes) and the amount of post-meal carbon and nitrogen returning to abdominal adipose tissue determines the final fat tissue mass.	Nitrogen	103-111	FAT atypical cadherin 1	Homo sapiens	171-174
23010571-5	2012	Recombinant ADAMTSL5 is a secreted, N-glycosylated 60kDa glycoprotein located in the subcellular matrix, on the cell-surface, and in the medium of transfected cells.	Nitrogen	36-37	ADAMTS-like 5	Mus musculus	12-20
34295263-8	2021	Therefore, meal arrangement at the time when muscle has the greatest reconstruction demand for carbon and nitrogen could decrease abdominal fat accumulation while increasing muscle mass and tissue repair.	Nitrogen	106-114	FAT atypical cadherin 1	Homo sapiens	140-143
34206784-17	2021	Pigs fed MTAF, AFP, and AFPA had lower (p < 0.05) urea nitrogen/creatinine than CON.	Nitrogen	55-63	alpha fetoprotein	Sus scrofa	15-18
22573871-7	2012	Using partial least squares discriminant analysis to investigate the N-glycosylation changes in colorectal cancer, an excellent separation and prediction ability were observed for both HILIC-HPLC and MALDI-TOF-MS data.	Nitrogen	69-70	FEZ family zinc finger 2	Homo sapiens	206-209
22573871-11	2012	In conclusion, the combination of HILIC and MALDI-TOF-MS profiling of N-glycans with multivariate statistical analysis demonstrated its potential for identifying N-glycosylation changes in colorectal cancer tissues and provided new leads that might be used as candidate biomarkers.	Nitrogen	70-71	FEZ family zinc finger 2	Homo sapiens	50-53
19508392-8	2009	KEY RESULTS: Mice treated with GSK-3 inhibitors showed decreased mortality, renal tubular dilatation, vacuolization and sloughing, blood urea nitrogen, creatinine and renal cell apoptosis in response to endotoxaemia.	Nitrogen	142-150	glycogen synthase kinase 3 beta	Mus musculus	31-36
34060819-2	2021	Watershed N inputs explained 51% of the variation in log-transformed stream total N (TN) concentrations.	Nitrogen	10-11	C-type lectin domain family 3 member B	Homo sapiens	85-87
19289571-6	2009	Hence, this novel RPNI chaperone activity is a consequence of N-glycosylation-dependent direct interaction with MOR.	Nitrogen	20-21	opioid receptor mu 1	Homo sapiens	112-115
22745059-9	2012	Its activity was not affected by core fucosylation or extensive fucosylation, antenna number, or sialylation, releasing several N-glycans from human lactoferrin and immunoglobulins A and G. Extensive N-deglycosylation of whole breast milk was also observed after coincubation with this enzyme.	Nitrogen	128-129	lactotransferrin	Bos taurus	149-160
34060819-2	2021	Watershed N inputs explained 51% of the variation in log-transformed stream total N (TN) concentrations.	Nitrogen	82-83	C-type lectin domain family 3 member B	Homo sapiens	85-87
22372734-3	2012	Expression of nucleoside transporters ENT1 and ENT3, together with nucleoside import, was increased upon nitrogen limitation.	Nitrogen	105-113	Major facilitator superfamily protein	Arabidopsis thaliana	47-51
34060819-3	2021	Both N source and input rates influenced stream NO3/TN ratios and N concentrations.	Nitrogen	5-6	C-type lectin domain family 3 member B	Homo sapiens	52-54
22777178-1	2012	Improving the solubility of polysubstituted 1,4-naphthoquinone derivatives was achieved by introducing nitrogen in two different positions of the naphthoquinone core, at C-5 and at C-8 of menadione through a two-step, straightforward synthesis based on the regioselective hetero-Diels-Alder reaction.	Nitrogen	103-111	complement C5	Homo sapiens	170-173
19409386-0	2009	The role of N-glycosylation in transport function and surface targeting of the human solute carrier PAT1.	Nitrogen	12-13	solute carrier family 36 member 1	Homo sapiens	100-104
34060819-4	2021	Streams dominated by oxidized N forms (NO3/TN ratio > 0.50) were more strongly responsive to the N input rate compared to streams dominated by other N forms.	Nitrogen	30-31	C-type lectin domain family 3 member B	Homo sapiens	43-45
22718772-4	2012	To elucidate the effect of N(alpha)-acetylation on the biophysical and biological properties of alpha-syn, we produced N(alpha)-acetylated alpha-syn first using a semisynthetic methodology based on expressed protein ligation (Berrade, L., and Camarero, J.	Nitrogen	27-29	synuclein alpha	Homo sapiens	96-105
19245243-1	2009	A new efficient synthetic method toward processable bis-N-annulated quaterrylene from easily available N-annulated perylene derivatives, which is conducted by DDQ/Sc(OTf)(3) oxidative coupling and ring fusion, is reported.	Nitrogen	56-57	POU class 5 homeobox 1	Homo sapiens	159-172
22733825-4	2012	In the present study, we have prepared a hex-2;hex-3 double mutant, which possesses a radically altered N-glycomic profile.	Nitrogen	104-105	Beta-N-acetylhexosaminidase	Caenorhabditis elegans	41-46
34060819-4	2021	Streams dominated by oxidized N forms (NO3/TN ratio > 0.50) were more strongly responsive to the N input rate compared to streams dominated by other N forms.	Nitrogen	97-98	C-type lectin domain family 3 member B	Homo sapiens	43-45
22441658-6	2012	(2) The level of ICAM-1 and TIMP-2 of serum in CO(2) and N(2) group after 2 weeks of pneumoperitoneum were higher than air group.	Nitrogen	57-61	TIMP metallopeptidase inhibitor 2	Rattus norvegicus	28-34
34060819-6	2021	By combining information about N inputs with climatic and landscape factors, random forest models of stream N concentrations explained 70, 58, and 60% of the spatial variation in stream concentrations of TN, dissolved inorganic N, and total organic N, respectively.	Nitrogen	31-32	C-type lectin domain family 3 member B	Homo sapiens	204-206
22441658-7	2012	(3) The expression of CD44v6, ICAM-1, MMP-2 and VEGF of tissue in CO(2) and N(2) group after 1, 2 and 4 weeks of pneumoperitoneum were lower than air group, TIMP-2 and ENS were higher than air group.	Nitrogen	76-80	vascular endothelial growth factor A	Rattus norvegicus	48-52
22441658-7	2012	(3) The expression of CD44v6, ICAM-1, MMP-2 and VEGF of tissue in CO(2) and N(2) group after 1, 2 and 4 weeks of pneumoperitoneum were lower than air group, TIMP-2 and ENS were higher than air group.	Nitrogen	76-80	TIMP metallopeptidase inhibitor 2	Rattus norvegicus	157-163
19206533-4	2009	To circumvent the low reactivity of the C-3 position, we developed a "SEM switch", which transposes the SEM-protecting group from one nitrogen to the other in one step, and in the process transforms the unreactive C-3 position to the reactive C-5 position.	Nitrogen	134-142	complement C5	Homo sapiens	243-246
34060819-6	2021	By combining information about N inputs with climatic and landscape factors, random forest models of stream N concentrations explained 70, 58, and 60% of the spatial variation in stream concentrations of TN, dissolved inorganic N, and total organic N, respectively.	Nitrogen	108-109	C-type lectin domain family 3 member B	Homo sapiens	204-206
19199636-2	2009	The chemical process involves two proton transfers, one from a carbon of the substrate to the nitrogen of Pro1 and another from this nitrogen atom to a different carbon of the substrate.	Nitrogen	94-102	lamin A/C	Homo sapiens	106-110
19199636-2	2009	The chemical process involves two proton transfers, one from a carbon of the substrate to the nitrogen of Pro1 and another from this nitrogen atom to a different carbon of the substrate.	Nitrogen	133-141	lamin A/C	Homo sapiens	106-110
19108612-0	2009	Copper powder-catalyzed regio- and stereoselective aminobromination of alpha,beta-unsaturated ketones with TsNH2 and NBS as nitrogen and halogen sources.	Nitrogen	124-132	nibrin	Homo sapiens	117-120
19108612-1	2009	The regio- and stereoselective aminobromination of alpha,beta-unsaturated ketones catalyzed by copper powder has been established with 4-TsNH(2) and NBS as the nitrogen/bromine sources, respectively.	Nitrogen	160-168	nibrin	Homo sapiens	149-152
22780441-2	2012	The study revealed that the mode of cyclization (exo vs endo) depends on the protecting group on nitrogen, the oxidation state of copper, and substitution on alkyne.	Nitrogen	97-105	mannosidase endo-alpha	Homo sapiens	56-60
22686285-6	2012	The overcrowding nature of the tethered PEG chains on the micelles was increased about 1.3-2.9 times with increasing N(agg) compared with the unperturbed state in solutions.	Nitrogen	117-118	progestagen associated endometrial protein	Homo sapiens	40-43
22467853-0	2012	The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.	Nitrogen	121-122	keratinocyte associated protein 2	Homo sapiens	55-59
22467853-8	2012	We show that KCP2 also influences protein N-glycosylation, yet in this case, the effect of its depletion is substrate specific, and is characterised by the accumulation of a novel STT3A-containing OST subcomplex.	Nitrogen	42-43	keratinocyte associated protein 2	Homo sapiens	13-17
22576951-3	2012	Because unmasking of the amino and carbonyl groups results in cyclic imines, these chiral building blocks are particularly useful for the asymmetric synthesis of functionalized nitrogen heterocycles, including prolines, pipecolic acids, pyrrolidines, homotropinones, tropinones, and tropane alkaloids such as cocaine and C-1 cocaine analogues.	Nitrogen	177-185	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	321-324
19200076-10	2009	Moreover, the N2 was specifically enhanced in Nogo trials.	Nitrogen	14-16	reticulon 4	Homo sapiens	46-50
34178943-7	2021	We have newly identified systemic site-specific N-glycosylation alterations underlying T2D patients in the complement activation pathways, including decreased levels of N-glycopeptides from C1s, MASP1, and CFP proteins, and increased levels of N-glycopeptides from C2, C4, C4BPA, C4BPB, and CFH.	Nitrogen	48-49	complement component 4 binding protein beta	Homo sapiens	280-285
34032101-2	2021	The spatial patterns of soil total nitrogen (TN) and phosphorus (TP) and the influencing factors in Jungar Banner were studied using classical statistical and geostatistical methods.	Nitrogen	35-43	C-type lectin domain family 3 member B	Homo sapiens	45-47
19093875-2	2009	The N-glycosylation determined by combination of Normal Phase-HPLC, Weak Anion Exchange-HPLC, exoglycosidase digestions and Mass Spectrometry revealed a complex mixture of neutral and monosialylated multiantennary N-glycans with variable number of alpha1-3-Gal-Gal antennae terminals.	Nitrogen	4-5	adrenoceptor alpha 1D	Homo sapiens	248-256
18951873-3	2008	The monkey group 1 CD1 isoforms contained amino acid residues and motifs known to be critical for intramolecular disulfide bond formation, N-linked glycosylation, and endosomal trafficking as in human group 1 CD1 molecules.	Nitrogen	139-140	CD1b molecule	Homo sapiens	19-22
22607976-4	2012	Folding and ER-associated degradation (ERAD) perturbation analyses revealed that prolonged TTR unfolding induces externalization of cryptic N-glycosylation site and triggers STT3B-dependent posttranslational N-glycosylation.	Nitrogen	208-209	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	174-179
22607976-7	2012	Hence we postulate that STT3B-dependent posttranslational N-glycosylation is part of a triage-salvage system recognizing cryptic N-glycosylation sites of secretory proteins to preserve protein homeostasis.	Nitrogen	58-59	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	24-29
22607976-7	2012	Hence we postulate that STT3B-dependent posttranslational N-glycosylation is part of a triage-salvage system recognizing cryptic N-glycosylation sites of secretory proteins to preserve protein homeostasis.	Nitrogen	129-130	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	24-29
22549002-3	2012	The induction of the heme oxygenase-1/biliverdin reductase-A (HO-1/BVR-A) system in the brain represents one of the earliest mechanisms activated by cells to counteract the noxious effects of increased reactive oxygen species and reactive nitrogen species.	Nitrogen	239-247	heme oxygenase 1	Homo sapiens	21-60
22549002-3	2012	The induction of the heme oxygenase-1/biliverdin reductase-A (HO-1/BVR-A) system in the brain represents one of the earliest mechanisms activated by cells to counteract the noxious effects of increased reactive oxygen species and reactive nitrogen species.	Nitrogen	239-247	heme oxygenase 1	Homo sapiens	62-66
34086719-1	2021	This study presents the application of a simultaneous method for the determination of total organic carbon (TOC) and total nitrogen (TN) in marine sediments and soils, using a data set of 206 samples collected from coastal lagoonal/marine sedimentary environments and certified reference materials (CRMs).	Nitrogen	123-131	C-type lectin domain family 3 member B	Homo sapiens	133-135
22511793-6	2012	By differential membrane extraction and sequential mutagenesis of potential N-glycosylation sites, we identified TMEM106B as a type 2 integral membrane protein with a highly glycosylated luminal domain.	Nitrogen	76-77	transmembrane protein 106B	Homo sapiens	113-121
22476036-0	2012	Four allantoinase genes are expressed in nitrogen-fixing soybean.	Nitrogen	41-49	allantoinase	Glycine max	5-17
19007158-10	2008	Monosubstituted [M(N)(PS)Cl(PPh(3))] species bearing the substitution-inert [M(N)(PS)](+) moieties act as suitable building blocks proposed for the construction of new classes of dissymmetrical nitrido compounds with potential application in the development of essential and target specific (99m)Tc and (188)Re radiopharmaceuticals for imaging and therapy, respectively.	Nitrogen	18-21	protein phosphatase 4 catalytic subunit	Homo sapiens	28-34
19054131-2	2008	It is especially useful for low abundance proteins, for example the GATA-factors (Gln3, Gat1) which activate nitrogen catabolite repression (NCR)-sensitive transcription.	Nitrogen	109-117	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	82-86
33871558-11	2021	Estimated glomerular filtration rate was higher and cystatin c was lower in LEU-PRO and LEU-PRO+n-3 postsupplementation compared with CON (all P < 0.05).	Nitrogen	96-97	cystatin C	Homo sapiens	52-62
18844342-1	2008	The reaction of [Pt(dmba)(PPh3)Cl] [where dmba = N,C-chelating 2-(dimethylaminomethyl)phenyl] with aqueous ammonia in acetone in the presence of AgClO4 gives the acetonimine complex [Pt(dmba)(PPh3)(NH=CMe2)]ClO4 (1).	Nitrogen	49-50	protein phosphatase 4 catalytic subunit	Homo sapiens	26-30
21546114-4	2012	In this review, we discuss the contributions of these domains with respect to L-selectin function: the regulation by serine phosphorylation of the cytoplasmic tail, the role of the transmembrane domain in receptor positioning on the cell surface as well as the N-glycosylation of the extracellular part and the identification of novel binding partners.	Nitrogen	261-262	selectin L	Homo sapiens	78-88
22270360-5	2012	Like the previously studied W26A mutation, N-methylation of Ile-20 dramatically reduced the ability of HNP1 to kill Staphylococcus aureus, inhibit LF, and bind gp120.	Nitrogen	43-44	HNP1	Homo sapiens	103-107
22270360-5	2012	Like the previously studied W26A mutation, N-methylation of Ile-20 dramatically reduced the ability of HNP1 to kill Staphylococcus aureus, inhibit LF, and bind gp120.	Nitrogen	43-44	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	160-165
18725511-7	2008	The highest contribution for the N-demethylation as calculated from the enzyme kinetic data, were obtained for CYP2B6 (R,S-MDMA), CYP1A2 (R-MDMA), and CYP2B6 (S-MDMA).	Nitrogen	33-34	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	130-136
18768906-3	2008	By studying CGL1-green fluorescent protein fusions in transient assays, we show that the extra N-glycosylation site created by a point mutation in cgl1 C5 is used in planta and interferes with folding of full-length membrane-anchored polypeptides in the endoplasmic reticulum.	Nitrogen	95-96	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	12-16
18768906-3	2008	By studying CGL1-green fluorescent protein fusions in transient assays, we show that the extra N-glycosylation site created by a point mutation in cgl1 C5 is used in planta and interferes with folding of full-length membrane-anchored polypeptides in the endoplasmic reticulum.	Nitrogen	95-96	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	147-151
18768906-5	2008	Complementation tests with C5-green fluorescent protein and other N-glycosylation variants of CGL1 demonstrated that suppression of aberrant N-glycosylation restores activity.	Nitrogen	66-67	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	94-98
18768906-5	2008	Complementation tests with C5-green fluorescent protein and other N-glycosylation variants of CGL1 demonstrated that suppression of aberrant N-glycosylation restores activity.	Nitrogen	141-142	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	94-98
18768906-11	2008	Besides demonstrating the conditional nature of cgl1 C5 in planta, our observations with loss-of-function alleles cgl1 C6 and cgl1-T in the stt3a-2 underglycosylation background prove that correct N-glycosylation is important for normal root growth and morphology in Arabidopsis.	Nitrogen	197-198	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	114-118
18768906-11	2008	Besides demonstrating the conditional nature of cgl1 C5 in planta, our observations with loss-of-function alleles cgl1 C6 and cgl1-T in the stt3a-2 underglycosylation background prove that correct N-glycosylation is important for normal root growth and morphology in Arabidopsis.	Nitrogen	197-198	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	114-118
22009112-0	2012	A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine.	Nitrogen	50-51	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	114-117
33991130-4	2021	We first synthesized 22 different nitrogen-containing bisphosphonate molecules that were designed to inhibit squalene synthase.	Nitrogen	34-42	farnesyl-diphosphate farnesyltransferase 1	Homo sapiens	109-126
22238349-9	2012	N-Acetylated cysteine was also inhibitory, but this inhibition was parallel with reduction in the oligomerization of H-ficolin and thus represents structural changes of the molecule.	Nitrogen	0-1	ficolin 3	Homo sapiens	117-126
18512733-2	2008	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia.	Nitrogen	12-13	syntaxin 1A	Homo sapiens	109-119
18512733-2	2008	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia.	Nitrogen	12-13	synaptosome associated protein 25	Homo sapiens	171-209
34073083-0	2021	Novel Approach for the Synthesis of Chlorophosphazene Cycles with a Defined Size via Controlled Cyclization of Linear Oligodichlorophosphazenes (Cl(PCl2=N)n-PCl3)+(PCl6).	Nitrogen	153-155	PHD finger protein 19	Homo sapiens	157-161
18512733-2	2008	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, which consists of Syntaxin1A, vesicle-associated membrane protein 2 (VAMP2) and synaptosomal-associated protein 25 kDa (SNAP25), plays an important role in the neurotransmitter system, and is therefore an attractive place to search for candidate genes for schizophrenia.	Nitrogen	12-13	synaptosome associated protein 25	Homo sapiens	211-217
18685424-10	2008	However, their chronic use in treating osteoporosis may result in adverse effects because basic nitrogen-containing cathepsin K inhibitors accumulate within acidic organelles such as lysosomes, thereby inhibiting the activity of other cathepsins.	Nitrogen	96-104	cathepsin K	Homo sapiens	116-127
18767679-0	2008	Treatment of coliphage MS2 with palladium-modified nitrogen-doped titanium oxide photocatalyst illuminated by visible light.	Nitrogen	51-59	MS2	Homo sapiens	23-26
18534984-7	2008	Both the Shh precursor and mature protein are N-palmitoylated by Hhat, and the reaction occurs during passage through the secretory pathway.	Nitrogen	46-47	sonic hedgehog signaling molecule	Homo sapiens	9-12
21203059-2	2008	The Mn(III) ion is hexa-coordinated by two N and two O atoms from two phenolate ligands and two N atoms from two azide ligands.	Nitrogen	43-44	hexosaminidase subunit alpha	Homo sapiens	19-23
18572897-2	2008	Metal monoxide-dinitrogen complexes, OM(N2) (M = Y, La) and OYNN, have been formed during sample deposition and identified on the basis of isotopic shifts, mixed isotopic splitting patterns, and CCl4-doping experiments.	Nitrogen	15-25	C-C motif chemokine ligand 4	Homo sapiens	195-199
19430540-3	2008	We have recently shown that Gln3 nuclear translocation in response to nitrogen source quality but not in response to rapamycin requires Golgi to endosome trafficking.	Nitrogen	70-78	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	28-32
18406109-1	2008	The complexes of dinitrogen with five cations (H(+), Li(+), Na(+), Be(2+) and Mg(2+)) up to four N(2) molecules have been calculated at the MP2/6-311++G(d,p) level.	Nitrogen	17-27	tryptase pseudogene 1	Homo sapiens	140-143
18510319-0	2008	Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.	Nitrogen	13-14	synuclein alpha	Homo sapiens	47-62
18300290-7	2008	Furthermore, a subset with a large N/C ratio expressing high levels of p63 was observed, as much as 25% among the limbal basal cell fraction, in contrast to only about 4% in the total limbal epithelial cells.	Nitrogen	35-36	tumor protein p63	Homo sapiens	71-74
18393486-10	2008	In this study, we show that rhodopsin is retained in supported bilayers of poly(bis-SorbPC) under ultra-high-vacuum conditions, on the basis of the increase in the XPS nitrogen concentration and the presence of characteristic amino acid peaks in the ToF-SIMS data.	Nitrogen	168-176	rhodopsin	Bos taurus	28-37
18340008-6	2008	Treatment of C-Angptl4 with PNGase F (an N-glycosidase) ablated its N-linked glycosylation, and also significantly attenuated its antiangiogenic activities.	Nitrogen	29-30	angiopoietin-like 4	Mus musculus	15-22
18238858-8	2008	These data suggest that UGT2B10 is likely the most active UGT isoform in human liver for the N-glucuronidation of TSNAs.	Nitrogen	93-94	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	24-31
18187349-2	2008	Isoelectrofocusing of plasma transferrin and apolipoprotein C-III showed abnormal patterns suggesting defective N- and O-glycosylation.	Nitrogen	112-113	apolipoprotein C3	Homo sapiens	45-65
18267938-4	2008	In addition, N-linked glycosylation of fibulin-5 does not require for the binding to tropoelastin.	Nitrogen	13-14	fibulin 5	Homo sapiens	39-48
18337470-1	2008	The second step of dolichol-linked oligosaccharide synthesis in the N-linked glycosylation pathway at the endoplasmic reticulum (ER) membrane is catalyzed by an unusual hetero-oligomeric UDP-N-acetylglucosamine transferase that in most eukaryotes is comprised of at least two subunits, Alg13p and Alg14p.	Nitrogen	68-69	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13	Saccharomyces cerevisiae S288C	286-292
18337470-7	2008	These data lead to the model that proteasomal degradation of excess unassembled Alg13p is an important quality control mechanism that ensures proper protein complex assembly and correct N-linked glycosylation.	Nitrogen	186-187	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13	Saccharomyces cerevisiae S288C	80-86
17822806-4	2008	Thus acylation of U-II(5-11) with small groups bearing nitrogen atoms could be instrumental in future studies for the identification of novel potent UT receptor ligands.	Nitrogen	55-63	urotensin 2	Homo sapiens	18-22
18249181-2	2008	Although most monoclonal antibodies have only one N-linked glycosylation site in the Fc region, N-linked glycosylation sites in the Fab region have also been observed.	Nitrogen	96-97	FA complementation group B	Homo sapiens	132-135
18295757-3	2008	Olanzapine was found to readily fit within the binding pocket of GSK-3beta in a low energy orientation characterized with optimal attractive interactions bridging the tricyclic thienobenzodiazepine nitrogen and sulfur atoms of olanzapine and the residue of VAL-135 of GSK-3beta.	Nitrogen	198-206	glycogen synthase kinase 3 beta	Mus musculus	65-74
18203712-1	2008	Cyclooxygenases (COX-1 and COX-2) are N-glycosylated, endoplasmic reticulum-resident, integral membrane proteins that catalyze the committed step in prostanoid synthesis.	Nitrogen	38-39	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	17-22
18311908-4	2008	In this study, the structural characteristics of nitrogen-containing compounds, which bind to the iron atom in two CYP isoforms (CYP2C9 and CYP3A4), were investigated.	Nitrogen	49-57	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	129-135
17975018-0	2008	N-linked glycosylation of VWF modulates its interaction with ADAMTS13.	Nitrogen	0-1	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	61-69
17986252-5	2008	Three members of the VID and GID gene families, VID30/GID1, GID2, and VID28/GID5 are needed for the rapamycin or nitrogen starvation-induced degradation of the high-affinity hexose transporter Hxt7p is shown here.	Nitrogen	113-121	glucose-induced degradation complex subunit VID28	Saccharomyces cerevisiae S288C	70-75
17986252-5	2008	Three members of the VID and GID gene families, VID30/GID1, GID2, and VID28/GID5 are needed for the rapamycin or nitrogen starvation-induced degradation of the high-affinity hexose transporter Hxt7p is shown here.	Nitrogen	113-121	glucose-induced degradation complex subunit VID28	Saccharomyces cerevisiae S288C	76-80
18288399-1	2008	Arylamine N-acetyltransferase type 1 (NAT1) is reported to be involved in the transfer of an acetyl group from acetyl-CoA to the terminal nitrogen of hydrazine and arylamine drugs or carcinogens.	Nitrogen	138-146	N-acetyltransferase 1	Homo sapiens	38-42
22148984-6	2012	Interestingly, stimulation of MIN6 beta-cells with glucose and the hormone GLP1, known stimulators of insulin secretion, causes significant changes in surface N-glycoproteome expression.	Nitrogen	32-33	zinc finger, GATA-like protein 1	Mus musculus	75-79
21625250-2	2012	To discover a possible mechanism of controlling the activation of MMCs, we investigated the expression and function of syntaxin4, one of the soluble membrane N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins, in RBL-2H3 cells, which is a rat mucosal mast cell line.	Nitrogen	158-159	syntaxin 4	Rattus norvegicus	119-128
22365192-10	2012	This event results in the occurrence of an additional alanine (A) residue in the protein that disrupts a putative atypical N-glycosylation site (VNGC/VNAGC) described in human lactadherin.	Nitrogen	123-124	milk fat globule EGF and factor V/VIII domain containing	Homo sapiens	176-187
22261343-6	2012	The degree of glycosylation in mature VEGF-D was reduced by eliminating one of the two N-glycosylation sites, and expressing the protein in Lec3.2.8.1 cells which had reduced glycosylation capacity.	Nitrogen	87-88	vascular endothelial growth factor D	Cricetulus griseus	38-44
22642118-10	2012	Inhibition of PC2 by N-acylated bicyclic guanidines (K(i) = 3.3-10 microM) or derivatives of pyrrolidin bispyperazines (K(i) = 0.54-10 microM) are considered too.	Nitrogen	21-22	proprotein convertase subtilisin/kexin type 2	Homo sapiens	14-17
22045697-1	2012	Gain-of-toxic mutations in the N-glycosylation motif of the seipin/BSCL2 gene (namely, the N88S and S90L mutations) cause autosomal dominant motor neuron diseases, termed "seipinopathy".	Nitrogen	31-32	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	60-66
22045697-1	2012	Gain-of-toxic mutations in the N-glycosylation motif of the seipin/BSCL2 gene (namely, the N88S and S90L mutations) cause autosomal dominant motor neuron diseases, termed "seipinopathy".	Nitrogen	31-32	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	67-72
21448924-10	2012	The inhibition of both the hexosamine pathway and N-linked glycosylation along with Wnt signaling pathway by sFRP1 and DKK1 is associated with significant decrease of the protein levels of GSK3beta, beta-catenin, and TXNIP RNA.	Nitrogen	50-51	catenin beta 1	Homo sapiens	199-211
21541742-5	2012	In this work, the complexes of 13 pi-hole-containing molecules with the nitrogen lone pairs of HCN and NH(3) have been characterized computationally using the MP2, M06-2X and B3PW91 procedures.	Nitrogen	72-80	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	95-98
22142473-3	2012	Here, we show that in GI-ME-N cells, BSO activates Nrf2 and up-regulates heme oxygenase-1 (HO-1).	Nitrogen	28-29	heme oxygenase 1	Homo sapiens	73-89
22142473-3	2012	Here, we show that in GI-ME-N cells, BSO activates Nrf2 and up-regulates heme oxygenase-1 (HO-1).	Nitrogen	28-29	heme oxygenase 1	Homo sapiens	91-95
22568819-1	2012	The O-acyl group at C-1 of two C19-diterpenoid alkaloids 2 and 5 was transferred to the secondary amine nitrogen to form amides 3 and 6 in the basic condition.	Nitrogen	104-112	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	20-23
22568819-2	2012	This kind of O-to-N intramolecular acyl migration could be caused by the near distance between the nucleophilic nitrogen atom and the carbonyl group of the ester at C-1 in the C19-diterpenoid alkaloids, which is consistent with the conformation of rings A and E in the C19-diterpenoid alkaloids.	Nitrogen	18-19	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	165-168
22568819-2	2012	This kind of O-to-N intramolecular acyl migration could be caused by the near distance between the nucleophilic nitrogen atom and the carbonyl group of the ester at C-1 in the C19-diterpenoid alkaloids, which is consistent with the conformation of rings A and E in the C19-diterpenoid alkaloids.	Nitrogen	112-120	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	165-168
22545002-3	2012	Enzymatic deglycosylation of human plasma-derived AGP (pdAGP) by Peptide: N-Glycosidase F yielded a mixture of differentially deglycosylated forms (PNGase-AGP), while the introduction of five Asn to Gln mutations in recombinant Pichia pastoris-derived AGP (rAGP-N(5)Q) eliminated N-linked glycosylation.	Nitrogen	74-75	N-glycanase 1	Homo sapiens	148-154
22266900-8	2012	Taken together, these data strongly support the proposal that KCP2 is a newly identified subunit of the N-glycosylation machinery present in a subset of eukaryotes.	Nitrogen	104-105	keratinocyte associated protein 2	Homo sapiens	62-66
20858066-6	2012	Two novel compounds we report (MP1 and MP2) covalently link ibuprofen and ketoprofen directly to the amide nitrogen of n-acetyl-glucosamine (NAG); the other compound (MP3) covalently links ibuprofen to the amide nitrogen, using a short chain acetyl linker.	Nitrogen	212-220	tryptase pseudogene 1	Homo sapiens	39-42
23139753-8	2012	Moreover, HE-4 is N-glycosylated and highly stable on a wide range of pH and temperature.	Nitrogen	18-19	WAP four-disulfide core domain 2	Homo sapiens	10-14
22363695-4	2012	Long-term Gas6 exposure induced production of a partially N-glycosylated form of Mer from newly synthesized stores of protein.	Nitrogen	58-59	growth arrest specific 6	Homo sapiens	10-14
22363695-4	2012	Long-term Gas6 exposure induced production of a partially N-glycosylated form of Mer from newly synthesized stores of protein.	Nitrogen	58-59	MER proto-oncogene, tyrosine kinase	Homo sapiens	81-84
22066525-2	2011	We have found that compounds possessing a nitrogen atom directly attached to the C-4 heterocycle ring possess in vitro Hsp90 inhibitory properties at least comparable to those of the structurally related 4,5-diarylisoxazole derivatives.	Nitrogen	42-50	complement C4A (Rodgers blood group)	Homo sapiens	81-84
22066525-2	2011	We have found that compounds possessing a nitrogen atom directly attached to the C-4 heterocycle ring possess in vitro Hsp90 inhibitory properties at least comparable to those of the structurally related 4,5-diarylisoxazole derivatives.	Nitrogen	42-50	heat shock protein 90 alpha family class A member 1	Homo sapiens	119-124
22047104-4	2011	Here we show that a seven-membered, nitrogen-containing heterocycle (3,4,5,6-tetrahydroxyazepane) scaffold is also promising for generating PCs for GCase.	Nitrogen	36-44	glucosylceramidase beta	Homo sapiens	148-153
21660532-7	2011	We found that manganese deficiency restricted uptake and transport of NO(3)(-), inhibited activities of nitrogen-metabolism-related enzymes, such as nitrate reductase, glutamine synthetase, and glutamic-oxaloace transaminase, thus decreasing the synthesis of chlorophyll and soluble protein, and inhibited the growth of maize seedlings.	Nitrogen	104-112	nitrate reductase [NADH] 1	Zea mays	149-166
21421995-4	2011	MALDI-TOF analysis of total N-linked glycoconjugates indicated a decrease in the relative amount of sialylated glycans in both COG3 KD and COG4 KD cells.	Nitrogen	28-29	component of oligomeric golgi complex 4	Homo sapiens	139-143
21519809-8	2011	The coding region of AMPD consists of 1,566 bp encoding 522 amino acids and possesses a transmembrane domain and two N-glycosylation sites.	Nitrogen	117-118	adenosine monophosphate deaminase 1	Homo sapiens	21-25
22051886-6	2011	Under normal growth conditions ugt76c2 had smaller seeds than the wild type, with accompanying lowered levels of active and N-glucosylated cytokinin forms.	Nitrogen	124-125	UDP-glucosyl transferase 76C2	Arabidopsis thaliana	31-38
21871142-4	2011	Milk yield, lactose, protein, non casein nitrogen, microbial features were affected by SCC level.	Nitrogen	41-49	serpin family B member 3	Homo sapiens	87-90
21816955-3	2011	Our results showed that phenylalkylamines with a distance between the aromatic ring and the positively charged amine nitrogen atom of ~6.4 A confer optimal interactions with PMAT, whereas studies with n-TAA compounds revealed an excellent correlation between IC(50) values and hydrophobicity.	Nitrogen	117-125	solute carrier family 29 member 4	Homo sapiens	174-178
21914816-3	2011	This study provides evidence that glutamine synthetase (GS), a key enzyme for root nodule metabolism, is a molecular target of NO in root nodules of Medicago truncatula, being regulated by tyrosine (Tyr) nitration in relation to active nitrogen fixation.	Nitrogen	236-244	LOC11405318	Medicago truncatula	34-54
21921115-1	2011	In seeds, glutamate decarboxylase (GAD) operates at the metabolic nexus between carbon and nitrogen metabolism by catalyzing the unidirectional decarboxylation of glutamate to form gamma-aminobutyric acid (GABA).	Nitrogen	91-99	glutamate decarboxylase	Arabidopsis thaliana	10-33
21921115-1	2011	In seeds, glutamate decarboxylase (GAD) operates at the metabolic nexus between carbon and nitrogen metabolism by catalyzing the unidirectional decarboxylation of glutamate to form gamma-aminobutyric acid (GABA).	Nitrogen	91-99	glutamate decarboxylase	Arabidopsis thaliana	35-38
21921115-10	2011	Taken together, these results indicate that the GAD-mediated conversion of glutamate to GABA during seed development plays an important role in balancing carbon and nitrogen metabolism and in storage reserve accumulation.	Nitrogen	165-173	glutamate decarboxylase	Arabidopsis thaliana	48-51
22027004-3	2011	We created an N-linked glycosylated form of this cytokine, hG-CSF (Phe140Asn), to assess its biological activity in the promyelocyte cell line HL60.	Nitrogen	14-15	colony stimulating factor 3	Homo sapiens	59-65
22027004-6	2011	These results suggest that the addition of N-linked glycosylation was successful in improving the biological activity of hG-CSF.	Nitrogen	43-44	colony stimulating factor 3	Homo sapiens	121-127
21527438-0	2011	N-glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1.	Nitrogen	0-1	proprotein convertase subtilisin/kexin type 1	Homo sapiens	108-113
21752865-11	2011	Our results confirm the theoretical predictions that BRI2 is N-glycosylated at Asn170 and show that this post-translational modification is essential for its expression at the cell surface but not for its proteolytic processing.	Nitrogen	61-62	integral membrane protein 2B	Homo sapiens	53-57
18189420-5	2008	The dominant H-NS binding sites, located at helix 3 as in Hha, reveal a common structural platform for H-NS binding.	Nitrogen	15-17	H-HA	Escherichia coli	58-61
18077452-0	2008	Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.	Nitrogen	0-1	jagged canonical Notch ligand 1	Homo sapiens	106-113
18207395-3	2008	N-methylation of the benzimidazole moiety within the lead structure significantly reduced P-gp susceptibility while increasing potency, giving rise to good brain penetration.	Nitrogen	0-1	phosphoglycolate phosphatase	Homo sapiens	90-94
18155731-8	2008	The experiments revealed that N induces the intrinsic apoptotic pathway, resulting in processing of N at residues 400 and 403 by caspase-6 and/or caspase-3.	Nitrogen	30-31	caspase 6	Homo sapiens	129-138
18155731-11	2008	In Vero E6 and A549 cells, a high proportion of N was cleaved by caspases.	Nitrogen	48-49	caspase 6	Homo sapiens	65-73
21637915-5	2011	Only the second peptide (emp#2), which contains a putative N-glycosylation site sequence, inhibited emmprin-stimulated production of MMP-2 in co-cultures of fibroblasts and several different human tumor cells types, including carcinoma, sarcoma, melanoma, leukemia and glioma cells.	Nitrogen	59-60	basigin (Ok blood group)	Homo sapiens	100-107
34063008-6	2021	The X-ray crystal structure of complexes {(Ag(3))(PF6)}  (4) and {(Ag(3))(SbF6)}  (6), where 3 is 3,3"-((1,1"-biphenyl)-2,2"-diyl)-6,6"-bis(phenyl)-1,2,4,5-tetrazine, revealed the formation of 1D polymeric chains, characterized by an evolution to a large opening of the original tweezer and a coordination of silver(I) via two chelating nitrogen atom and some C=C pi-interactions.	Nitrogen	337-345	sperm associated antigen 17	Homo sapiens	50-53
21486309-0	2011	Water-use efficiency and nitrogen-use efficiency of C(3) -C(4) intermediate species of Flaveria Juss.	Nitrogen	25-33	complement C4A (Rodgers blood group)	Homo sapiens	58-62
21486309-2	2011	Plants using the C(4) pathway of carbon metabolism are marked by greater photosynthetic water and nitrogen-use efficiencies (PWUE and PNUE, respectively) than C(3) species, but it is unclear to what extent this is the case in C(3) -C(4) intermediate species.	Nitrogen	98-106	complement C4A (Rodgers blood group)	Homo sapiens	17-21
21949153-8	2011	Removal of the critical N-terminal Ser-rich region or either of the two Tyr-dependent sorting motifs from RTNLB1 causes partial reversion of the negative effects of excess RTNLB1 on FLS2 transport out of the ER and accumulation at the membrane.	Nitrogen	24-25	VIRB2-interacting protein 1	Arabidopsis thaliana	172-178
21302143-4	2011	Culture conditions were optimized, and the highest lipase production was observed in basal medium with corn steep liquor as nitrogen source and glucose as carbon source.	Nitrogen	124-132	lipase	Zea mays	51-57
17998299-11	2008	Consistent with these observations, hecogenin, a selective inhibitor of UGT1A4, selectively inhibited the N-glucuronidation, whereas diclofenac, a potent inhibitor of UGT2B7, had a greater inhibitory effect on the O-glucuronidation than on the N-glucuronidation.	Nitrogen	106-107	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	72-78
17591721-3	2008	The results lend support to the experimental proposal that the nitrogen analogue of the SAM coenzyme should be a practicable inhibitor for the catalytic methyl transfer by HemK.	Nitrogen	63-71	HemK methyltransferase family member 1	Homo sapiens	172-176
17980356-7	2008	Docking of the most potent compound into the active site of human butyrylcholinesterase showed that the lowest energy model had two benzene rings oriented towards Trp 82 and Tyr 332 whereas the positively charged nitrogen group was stabilized by Trp 231.	Nitrogen	213-221	butyrylcholinesterase	Homo sapiens	66-87
18942697-6	2008	The equations are tested for an external set of 99 additional compounds including very different nitrogen bases such as ortho-substituted pyridines, polyazines and azoles.Theoretical calculations give a reliable estimation of hydrogen-bond basicity provided that the populations of the different isomers of the bases are taken into account by using the Boltzmann law, and that a specific halogen-bond interaction with the solvent CCl4 is considered for polybasic molecules.The pKHB scale can thus be extended to important classes of species experimentally inaccessible in CCl4, to polynitrogen compounds and to molecules of biological significance.	Nitrogen	97-105	C-C motif chemokine ligand 4	Homo sapiens	430-434
18942697-6	2008	The equations are tested for an external set of 99 additional compounds including very different nitrogen bases such as ortho-substituted pyridines, polyazines and azoles.Theoretical calculations give a reliable estimation of hydrogen-bond basicity provided that the populations of the different isomers of the bases are taken into account by using the Boltzmann law, and that a specific halogen-bond interaction with the solvent CCl4 is considered for polybasic molecules.The pKHB scale can thus be extended to important classes of species experimentally inaccessible in CCl4, to polynitrogen compounds and to molecules of biological significance.	Nitrogen	97-105	C-C motif chemokine ligand 4	Homo sapiens	572-576
21570947-0	2011	Role of the putative N-glycosylation and PKC-phosphorylation sites of the human sodium-dependent multivitamin transporter (hSMVT) in function and regulation.	Nitrogen	21-22	solute carrier family 5 member 6	Homo sapiens	80-121
21570947-0	2011	Role of the putative N-glycosylation and PKC-phosphorylation sites of the human sodium-dependent multivitamin transporter (hSMVT) in function and regulation.	Nitrogen	21-22	solute carrier family 5 member 6	Homo sapiens	123-128
34723132-4	2021	While higher pyrolysis temperature increased the specific surface area (as determined by BET nitrogen adsorption), it did not affect the total observed porosity.	Nitrogen	93-101	delta/notch like EGF repeat containing	Homo sapiens	89-92
21570947-2	2011	The human SMVT (hSMVT) polypeptide is predicted to have four N-glycosylation sites and two putative PKC phosphorylation sites but their role in the function and regulation of the protein is not known and was examined in this investigation.	Nitrogen	61-62	solute carrier family 5 member 6	Homo sapiens	10-14
21570947-2	2011	The human SMVT (hSMVT) polypeptide is predicted to have four N-glycosylation sites and two putative PKC phosphorylation sites but their role in the function and regulation of the protein is not known and was examined in this investigation.	Nitrogen	61-62	solute carrier family 5 member 6	Homo sapiens	16-21
21570947-4	2011	Studies utilizing site-directed mutagenesis revealed that the N-glycosylation sites at positions Asn(138) and Asn(489) are important for the function of hSMVT and that mutating these sites significantly reduces the V(max) of the biotin uptake process.	Nitrogen	62-63	solute carrier family 5 member 6	Homo sapiens	153-158
18196509-7	2008	C-to-N isomerizations proceed by the above-mentioned intramolecular process, with a temperature-dependent contribution from the formation and cleavage of mu2-C,N coordination dimers [{Ru{CH(CN)SO2Ph}(Cp)(PPh3)}2] (15 and 16).	Nitrogen	5-6	protein phosphatase 4 catalytic subunit	Homo sapiens	204-208
18752233-3	2008	Calculations showed that both heteroatoms are capable of accelerating the ring closure by stabilizing the partial positive charge which develops at C-6 (C-2) in the transition state, with S-heterocyclic derivatives being more reactive than the corresponding N-containing compounds.	Nitrogen	258-259	complement C2	Homo sapiens	153-156
21490130-4	2011	To elucidate the mechanisms regulating oxidative stress-induced apoptosis in vivo, we fed heterozygous SOD2(Het), Gpx4(Het), and transgenic Gpx4(Tg) mice diets containing either 15% corn oil by weight (CO, enriched in n-6 PUFA) or 3.5% CO + 11.5% fish oil (FO, enriched in n-3 PUFA) for 4 weeks.	Nitrogen	22-23	glutathione peroxidase 4	Mus musculus	140-144
34234043-3	2021	The grinding of soil samples with liquid nitrogen followed by a lysozyme treatment at 45 C for 1 h and an incubation with protease and SDS at 50 C for 5 h increased the size and yield of HMW DNA extracted from these samples.	Nitrogen	41-49	cilia and flagella associated protein 97	Homo sapiens	187-190
21277709-2	2011	The 118A&gt;G (rs1799971) polymorphism in exon 1 of the mu-opioid receptor gene (OPRM1) leads to an Asn40Asp amino acid change that affects a putative N-glycosylation site.	Nitrogen	151-152	opioid receptor mu 1	Homo sapiens	81-86
17906858-8	2008	When both factors were included in the multivariate model, both N status and the (99m)Tc-HYNIC Annexin-V T/N ratio showed an independent association with overall survival (p = 0.001 for lymph node status and 0.000 for dichotomized (99m)Tc-HYNIC Annexin-V T/N ratio).	Nitrogen	91-92	annexin A5	Homo sapiens	95-104
35623134-1	2022	Dipeptidyl peptidase III (DPP3) is a ubiquitously expressed zinc-dependent peptide cutting enzyme and selectively hydrolyses amide bonds to cleave N-terminal dipeptide fragments off of physiologically important oligopeptides.	Nitrogen	147-148	dipeptidyl peptidase 3	Homo sapiens	0-24
17956937-8	2008	The results suggest that identification of alpha2,3-linked sialic acids on PSA potentially discriminates malignant from benign conditions, if the analysis is applied to oligosaccharides specifically attached to the N-glycosylation site of PSA in either a free or a complexed form in the serum.	Nitrogen	215-216	kallikrein related peptidase 3	Homo sapiens	75-78
18039741-2	2008	Its discovery as the endothelium-derived relaxing factor (EDRF) by Ignarro revolutionized how NO and cognate reactive nitrogen intermediates, which were previously considered to be toxic molecules, are viewed.	Nitrogen	118-126	alpha hemoglobin stabilizing protein	Homo sapiens	21-56
18039741-2	2008	Its discovery as the endothelium-derived relaxing factor (EDRF) by Ignarro revolutionized how NO and cognate reactive nitrogen intermediates, which were previously considered to be toxic molecules, are viewed.	Nitrogen	118-126	alpha hemoglobin stabilizing protein	Homo sapiens	58-62
18089754-2	2008	The cationic amino acid transporter type 1 (CAT1) paralogues of murine NIH 3T3 and MDTF cells (mCAT1 and dCAT1, respectively) contain two conserved N-linked glycosylation sites in the third extracellular loop (ECL3, the putative Mo-MLV binding site).	Nitrogen	71-72	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	4-42
18089754-2	2008	The cationic amino acid transporter type 1 (CAT1) paralogues of murine NIH 3T3 and MDTF cells (mCAT1 and dCAT1, respectively) contain two conserved N-linked glycosylation sites in the third extracellular loop (ECL3, the putative Mo-MLV binding site).	Nitrogen	71-72	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	44-48
21535396-5	2011	Site-specific mutagenesis of one or more potential N-linked glycosylation sites in TF was used to generate TF mutants lacking glycans.	Nitrogen	51-52	coagulation factor III, tissue factor	Homo sapiens	83-85
21535396-5	2011	Site-specific mutagenesis of one or more potential N-linked glycosylation sites in TF was used to generate TF mutants lacking glycans.	Nitrogen	51-52	coagulation factor III, tissue factor	Homo sapiens	107-109
21518214-3	2011	First, we showed that FIAF was present in different isoforms, and secreted as N-glycosylated proteins, exclusively at the basal side of the cell monolayer.	Nitrogen	78-79	angiopoietin like 4	Homo sapiens	22-26
21515579-2	2011	The zinc cluster protein Dal81 is a general activator of nitrogen metabolic genes, including those for gamma-aminobutyrate (GABA).	Nitrogen	57-65	Dal81p	Saccharomyces cerevisiae S288C	25-30
21527779-4	2011	Molecular genetic methods confirmed the role of the Ivory Coast variant of CDC28 in the arrangement of spores after meiosis, in the shape of budding cells in rich medium and in the morphology of filamentous growth during nitrogen limitation.	Nitrogen	221-229	cyclin-dependent serine/threonine-protein kinase CDC28	Saccharomyces cerevisiae S288C	75-80
18279246-4	2008	A pulsed nitrogen laser can be focused onto a pen stroke from a pigmented ink pen on paper, and positive and negative ions representative of the pigment can be generated for subsequent mass spectrometric analysis.	Nitrogen	9-17	proprotein convertase subtilisin/kexin type 1 inhibitor	Homo sapiens	46-49
21769758-0	2011	N-linked glycosylation of mouse adiponectin.	Nitrogen	0-1	adiponectin, C1Q and collagen domain containing	Mus musculus	32-43
35623134-1	2022	Dipeptidyl peptidase III (DPP3) is a ubiquitously expressed zinc-dependent peptide cutting enzyme and selectively hydrolyses amide bonds to cleave N-terminal dipeptide fragments off of physiologically important oligopeptides.	Nitrogen	147-148	dipeptidyl peptidase 3	Homo sapiens	26-30
21769758-7	2011	To further clarify the N-glycosylation of adiponectin, we investigated the effect of N-glycosylation inhibitor tunicamycin on 3T3-L1 adipocytes.	Nitrogen	23-24	adiponectin, C1Q and collagen domain containing	Mus musculus	42-53
18279246-4	2008	A pulsed nitrogen laser can be focused onto a pen stroke from a pigmented ink pen on paper, and positive and negative ions representative of the pigment can be generated for subsequent mass spectrometric analysis.	Nitrogen	9-17	proprotein convertase subtilisin/kexin type 1 inhibitor	Homo sapiens	78-81
21769758-9	2011	This result also indicates the possibility that slower band of adiponectin is N-glycosylated.	Nitrogen	78-79	adiponectin, C1Q and collagen domain containing	Mus musculus	63-74
35341854-4	2022	The bulk deposition fluxes of total nitrogen (TN) and total phosphorus (TP) over the network were 27.5 kg N ha-1 yr-1 and 0.92 kg P ha-1 yr-1, respectively.	Nitrogen	36-44	solute carrier family 9 member B1	Homo sapiens	106-117
21769758-10	2011	Lastly, to identify glycosylated asparagine residues, we established 3T3-L1 cell lines stably expressing wild type and mutant adiponectin in N-glycosylation sites.	Nitrogen	141-142	adiponectin, C1Q and collagen domain containing	Mus musculus	126-137
21769758-12	2011	These results suggest that a part of mouse adiponectin is modified by N-linked glycosylation at asparagine 53.	Nitrogen	70-71	adiponectin, C1Q and collagen domain containing	Mus musculus	43-54
18776629-1	2008	Using succinonitrile as a sole source of carbon and nitrogen, two bacterium strains named as J-1-3 and J-13-1 were isolated and screened out from the treatment facilities of Shanghai petrochemical wastewater treatment plant treating acrylic fiber production wastewater.	Nitrogen	52-60	immunoglobulin kappa joining 1	Homo sapiens	93-98
18419081-5	2008	At the same growth stage, the protease, catalase and dehydrogenase activities in rhizosphere soil of the two cultivars increased with increasing nitrogen application rate and peaked at 180 kg N x hm(-2).	Nitrogen	145-153	catalase-1	Triticum aestivum	40-48
21503583-4	2011	Our aim was to investigate the expression of the prostate stem cell antigen (PSCA), a highly N-glycosylated phosphatidylinositol (GPI)-anchored cell surface protein, in gliomas of different WHO grades in order to evaluate its potential as a diagnostic marker and as a target for immunotherapy.	Nitrogen	93-94	prostate stem cell antigen	Homo sapiens	49-75
21503583-4	2011	Our aim was to investigate the expression of the prostate stem cell antigen (PSCA), a highly N-glycosylated phosphatidylinositol (GPI)-anchored cell surface protein, in gliomas of different WHO grades in order to evaluate its potential as a diagnostic marker and as a target for immunotherapy.	Nitrogen	93-94	prostate stem cell antigen	Homo sapiens	77-81
35390659-8	2022	Based on the quantification of nonlinearity, we clustered all the samples of water quality responses using K-Means, an unsupervised Machine Learning algorithm, to find the potential types of nonlinear water quality responses for TN (total nitrogen), TP (total phosphorus), and Chla (chlorophyll a).	Nitrogen	239-247	C-type lectin domain family 3 member B	Homo sapiens	229-231
17877336-2	2007	Rotationally resolved infrared spectra are reported for the CH stretching vibration of the linear nitrogen-bound HCN-Ga and HCN-In complexes that show significant perturbation due to spin-orbit coupling of the 2Pi1/2 ground state with the 2Sigma1/2 state which are degenerate at long range.	Nitrogen	98-106	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	113-116
17877336-2	2007	Rotationally resolved infrared spectra are reported for the CH stretching vibration of the linear nitrogen-bound HCN-Ga and HCN-In complexes that show significant perturbation due to spin-orbit coupling of the 2Pi1/2 ground state with the 2Sigma1/2 state which are degenerate at long range.	Nitrogen	98-106	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	124-127
17877336-4	2007	A nitrogen-bound HCN-Al complex is not observed, which is attributed to reaction, even at 0.37 K. This conclusion is supported by the observation of a weakly bound complex containing two HCN"s and one Al atom which, from the analysis of its rotationally resolved zero-field and Stark spectra is assigned to a weakly bound complex of a HCNAl reaction product and a second HCN molecule.	Nitrogen	2-10	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	17-20
17951033-5	2007	The main routes of cyamemazine biotransformation are N-mono-demethylation (CYP1A2, CYP3A4 and CYP2C8) and mono-oxidation (either S-oxidized or hydroxylated derivatives which could not be discriminated because characterized by the same mass value) by CYP1A2 and CYP2C9.	Nitrogen	53-54	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	75-81
21829377-5	2011	In addition to genes in the n-3 pathway, we identified a novel association of DPA with several SNPs in GCKR (glucokinase regulator, p = 1 x 10-8).	Nitrogen	1-2	glucokinase regulator	Homo sapiens	103-107
21498885-8	2011	Consistent with our hypothesis, IC(50) values for ARH3 inhibition by 2""- and 3""-N-acetyl-ADPr analogs of OAADPr were significantly higher than that for ADPr.	Nitrogen	82-83	ADP-ribosylserine hydrolase	Homo sapiens	50-54
18065096-8	2007	Thus, the present study shows that in benzomorphan-based ligands the presence of different functional groups in the nitrogen substituent, ranging from a positive charged amine to an additional aromatic ring, is able to promote the correct aligment of aromatic pharmacophoric residues with MOP and KOP receptor types.	Nitrogen	116-124	opioid receptor mu 1	Homo sapiens	289-292
35491865-0	2022	LINC00173 Promotes Wilms" Tumor Progression Through MGAT1-mediated MUC3A N-glycosylation.	Nitrogen	73-74	long intergenic non-protein coding RNA 173	Homo sapiens	0-9
18065096-8	2007	Thus, the present study shows that in benzomorphan-based ligands the presence of different functional groups in the nitrogen substituent, ranging from a positive charged amine to an additional aromatic ring, is able to promote the correct aligment of aromatic pharmacophoric residues with MOP and KOP receptor types.	Nitrogen	116-124	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	297-300
35491865-12	2022	In summary, our study first discovered that LINC00173 promoted WT progression through MGAT1-mediated MUC3A N-glycosylation, giving new clues to further understanding the mechanism underlying WT progression.	Nitrogen	107-108	long intergenic non-protein coding RNA 173	Homo sapiens	44-53
21498512-7	2011	Such selective modification enabled the generation of an internal standard, (15)N-labeled CYP27A1 modified with iso[4]LGE(2), for the subsequent analysis of a human retinal sample.	Nitrogen	80-81	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	90-97
35367940-9	2022	The total nitrogen (TN): total phosphorous (TP) ratio was reduced after management intervention, causing an increase in the abundance of cyanobacteria that may contribute to the increase of rotifer synchrony in autumn.	Nitrogen	10-18	C-type lectin domain family 3 member B	Homo sapiens	20-22
21501579-2	2011	Diethyl and dibutyl [alpha-anilino-(quinolin-2-ylmethyl)]phosphonates (L1, L2) act as N,N-chelate ligands through the quinoline and aniline nitrogens giving complexes cis-[Pd(L1/L2)X(2)] (X Cl, Br) (1-4).	Nitrogen	140-149	CD274 molecule	Homo sapiens	172-177
17576790-2	2007	Using an improved analytical method, we have discovered that the human UDP-glucuronosyltransferase (UGT) 2B10, a liver enzyme previously unknown to conjugate nicotine or exhibit considerable activity toward any compound, plays a major role in nicotine inactivation by direct conjugation with glucuronic acid at the aromatic nitrogen atom.	Nitrogen	324-332	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	71-109
17675106-1	2007	We investigated whether increased heme oxygenase (HO)-1 activity by NS-398 is responsible for protection against hypoxia-induced damage in C6 cells.	Nitrogen	68-70	heme oxygenase 1	Homo sapiens	34-55
35548860-4	2022	We evidence here, by quantitative operando X-ray absorption spectroscopy, that the initial Ir single atoms are coordinated with four light atoms i.e., Ir-X4 (X = C/N/O) with an oxidation state of +3.2.	Nitrogen	164-165	iroquois homeobox 4	Homo sapiens	151-156
17675106-3	2007	NS-398 increased HO-1 expression in a concentration- and time-dependent manner during both normoxia and hypoxia (95% N(2)/5% CO(2)), but the latter was much more sensitive.	Nitrogen	0-2	heme oxygenase 1	Homo sapiens	17-21
17675106-3	2007	NS-398 increased HO-1 expression in a concentration- and time-dependent manner during both normoxia and hypoxia (95% N(2)/5% CO(2)), but the latter was much more sensitive.	Nitrogen	117-121	heme oxygenase 1	Homo sapiens	17-21
21524275-3	2011	PEPC also fulfils a broad spectrum of non-photosynthetic functions, particularly the anaplerotic replenishment of tricarboxylic acid cycle intermediates consumed during biosynthesis and nitrogen assimilation.	Nitrogen	186-194	phosphoenolpyruvate carboxykinase 1	Homo sapiens	0-4
35605769-5	2022	ML-based feature importance indicated that nitrogen content of biomass, solid content, and temperature were the top three critical features for pH, TN, and TP, while those for TOC were reaction time, lipid, and temperature.	Nitrogen	43-51	C-type lectin domain family 3 member B	Homo sapiens	148-150
21554732-12	2011	CONCLUSIONS: These data demonstrated that over-expression of alpha-synuclein drives microglial cells into a form of reactive phenotype characterized by elevated levels of arachidonic acid metabolizing enzymes, cytokine secretion, and reactive nitrogen species secretion all superimposed upon impaired phagocytic potential.	Nitrogen	243-251	synuclein, alpha	Mus musculus	61-76
21524545-12	2011	The urea transporter B mRNA abundance in rumen papillae (papillae harvested at sampling days) was not affected by dietary N supply.	Nitrogen	25-26	solute carrier family 14 member 1	Bos taurus	4-22
21524545-15	2011	No association between long-term adaptation of urea-N extraction across the rumen wall and urea transporter B mRNA abundance could be demonstrated.	Nitrogen	0-1	solute carrier family 14 member 1	Bos taurus	91-109
21524550-0	2011	Short communication: Effects of dietary nitrogen concentration on messenger RNA expression and protein abundance of urea transporter-B and aquaporins in ruminal papillae from lactating Holstein cows.	Nitrogen	40-48	solute carrier family 14 member 1	Bos taurus	116-134
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	solute carrier family 14 member 1	Bos taurus	121-139
17518451-4	2007	All monoligated species reported here are bound through the nitrogen end of the HCN molecule.	Nitrogen	60-68	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	80-83
17522223-2	2007	Here, we delineate the N-linked glycosylation (N-glycan) sites in gp120 that contribute to optimal DC-SIGN binding.	Nitrogen	23-24	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	66-71
35605776-4	2022	Under optimal conditions, AOBR with MBF carriers could remove 91% chemical oxygen demand (COD) and 81% total nitrogen (TN), with biomass production increased by 7.6%, 4.5% and 8.7% in three successive anaerobic compartments compared to the control.	Nitrogen	109-117	C-type lectin domain family 3 member B	Homo sapiens	119-121
17439949-0	2007	Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation.	Nitrogen	100-108	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	18-22
17439949-2	2007	Gln3 is cytoplasmic in cells provided with repressive nitrogen sources such as glutamine and is nuclear in cells growing with a derepressive nitrogen source such as proline or those treated with rapamycin or methionine sulfoximine (Msx).	Nitrogen	54-62	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
17439949-2	2007	Gln3 is cytoplasmic in cells provided with repressive nitrogen sources such as glutamine and is nuclear in cells growing with a derepressive nitrogen source such as proline or those treated with rapamycin or methionine sulfoximine (Msx).	Nitrogen	141-149	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
17451431-1	2007	CD98 heavy chain (CD98hc), expressed at high levels in developing human trophoblasts, is an integral membrane protein with multiple N-linked glycosylation sites and known to be important for cell fusion, adhesion, and amino acid transport.	Nitrogen	132-133	solute carrier family 3 member 2	Homo sapiens	0-16
17451431-1	2007	CD98 heavy chain (CD98hc), expressed at high levels in developing human trophoblasts, is an integral membrane protein with multiple N-linked glycosylation sites and known to be important for cell fusion, adhesion, and amino acid transport.	Nitrogen	132-133	solute carrier family 3 member 2	Homo sapiens	18-24
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	solute carrier family 14 member 1	Bos taurus	141-145
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	solute carrier family 14 member 1	Bos taurus	214-218
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	aquaporin 8	Bos taurus	235-239
21524550-1	2011	To test the hypothesis that dietary N concentrations affect gut epithelial urea transport by modifying the expression of urea transporter B (UT-B) and aquaporins (AQP), the mRNA expression and protein abundance of UT-B and AQP3, AQP7, AQP8, and AQP10 were investigated in ruminal papillae from 9 lactating dairy cows.	Nitrogen	36-37	aquaporin 10	Bos taurus	245-250
20609377-7	2011	Some IO&amp;NS-related pathways, like the induction of indoleamine 2-3-dioxygenase, neurodegeneration and decreased neurogenesis, are more specific to depression, whereas other pathways, like the 2"-5" oligoadenylate synthetase/RNase L pathway, are specific to ME/CFS.	Nitrogen	12-14	ribonuclease L	Homo sapiens	228-235
35093357-4	2022	A meta-analysis of 97 studies reported from 2000 to 2021 from different countries showed that the mean global N fertilizer input in orchards was 303 kg N ha-1 yr-1, and the estimated emission factor (EF) of nitrous oxide (N2O) and ammonia (NH3) were 1.39% and 3.64%, respectively.	Nitrogen	110-111	solute carrier family 9 member B1	Homo sapiens	152-163
21413704-1	2011	Four diastereomeric series of N-alkylated [6+5] bicyclic isoureas having hydroxyl substituents mimicking glucose hydroxyl groups have been synthesized as potential beta-glucocerebrosidase (GCase) inhibitors with the aim of developing pharmacological chaperones for enzyme deficiency in Gaucher disease (GD).	Nitrogen	30-31	glucosylceramidase beta	Homo sapiens	164-187
21413704-1	2011	Four diastereomeric series of N-alkylated [6+5] bicyclic isoureas having hydroxyl substituents mimicking glucose hydroxyl groups have been synthesized as potential beta-glucocerebrosidase (GCase) inhibitors with the aim of developing pharmacological chaperones for enzyme deficiency in Gaucher disease (GD).	Nitrogen	30-31	glucosylceramidase beta	Homo sapiens	189-194
17633104-6	2007	Interestingly, the N88S and S90L mutations both disturb the N-glycosylation motif, suggesting that improper glycosylation of seipin is closely associated with the pathogenesis of motor neuron diseases.	Nitrogen	19-20	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	125-131
35093357-10	2022	Average N input (405 kg N ha-1 yr-1) and Nr loss (102 kg N ha-1 yr-1) of orchards in Asia were the highest.	Nitrogen	41-43	solute carrier family 9 member B1	Homo sapiens	57-68
17369258-4	2007	The N terminus of the SDN-1 contains a Ser-Gly proteoglycan site at Ser(71), flanked by potential mucin and N-glycosylation sites.	Nitrogen	4-5	Syndecan;putative syndecan	Caenorhabditis elegans	22-27
35511725-0	2022	Influence of N-glycosylation in the A and C domains on the immunogenicity of factor VIII.	Nitrogen	13-14	coagulation factor VIII	Mus musculus	77-88
17324383-10	2007	In addition, preventing N-glycosylation decreased cell surface Kv1.2 expression levels by approximately 40% primarily by increasing partial endoplasmic reticulum retention and this effect was completely rescued by Kv1.4 subunits, which are glycosylated, but not by cytoplasmic Kvbeta2.1 subunits.	Nitrogen	24-25	potassium voltage-gated channel subfamily A member 4	Homo sapiens	214-219
21435448-4	2011	The administration of DT to B6.Foxp3(DTR) recipients with accepted DBA/2 kidneys, 3 weeks to 3 months after transplantation, caused a marked depletion of Foxp3 cells and triggered acute cellular rejection, manifested by a sudden increase in blood urea nitrogen within a week.	Nitrogen	252-260	heparin-binding EGF-like growth factor	Mus musculus	37-40
35511725-4	2022	We investigated the potential roles of four N-glycosylation sites including N41 and N239 in the A1 domain, N1810 in the A3 domain, and N2118 in the C1 domain of FVIII in moderating its immunogenicity.	Nitrogen	44-45	coagulation factor VIII	Mus musculus	161-166
21148207-6	2011	QDR3 transcript levels were also found to increase under nitrogen or amino acid limitation; this regulation is also dependent on Gcn4.	Nitrogen	57-65	Qdr3p	Saccharomyces cerevisiae S288C	0-4
35511725-11	2022	These results indicate that N-glycosylation of FVIII can have significant impact on its immunogenicity.	Nitrogen	28-29	coagulation factor VIII	Mus musculus	47-52
17307004-5	2007	The cDNA for zLIF encoded a predicted 215-amino acid protein with a putative 32-amino acid signal peptide, two disulfide bonds, and two N-linked glycosylation sites.	Nitrogen	6-7	IL-6 subfamily cytokine M17	Danio rerio	13-17
35351554-0	2022	Response of nitrogen removal performance and microbial community to a wide range of pH in thermophilic denitrification system.	Nitrogen	12-20	phenylalanine hydroxylase	Homo sapiens	84-86
17335276-3	2007	Related tetradentate ligand CRH formed a low-spin iron(II) complex (meso form was structurally characterized) with a planar arrangement of the four nitrogen atoms from the macrocycle and two axial acetonitrile molecules.	Nitrogen	148-156	corticotropin releasing hormone	Homo sapiens	28-31
21138434-0	2011	The identification of N-glycosylated residues of the human 5-HT3B receptor subunit: importance for cell membrane expression.	Nitrogen	22-23	5-hydroxytryptamine receptor 3B	Homo sapiens	59-65
35133011-4	2022	Here, we report that ETHYLENE-INSENSITIVE3-LIKE1 (OsEIL1) acts as a key transcription factor regulating OsVTC1-3-dependent NH4 + efflux and protein N-glycosylation in rice grown under NH4 + nutrition.	Nitrogen	148-149	Ethylene insensitive 3 family protein	Arabidopsis thaliana	21-42
21081470-3	2011	Metabolism of PhIP by CYP1A2 differs considerably between humans and rodents, with more N(2)-hydroxylation (activation) and less 4"-hydroxylation (detoxication) in humans.	Nitrogen	88-92	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	22-28
20959627-11	2011	Altogether the results suggest that GLN1;2 is essential for nitrogen assimilation under ample nitrate supply and for ammonium detoxification.	Nitrogen	60-68	hypothetical protein	Arabidopsis thaliana	36-42
21142011-3	2011	The method is applied to 15N relaxation of N-H bonds in the Rho GTPase binding (RBD) domain of plexin-B1, which exhibits intricate internal mobility.	Nitrogen	27-28	plexin B1	Homo sapiens	95-104
21463857-4	2011	WSB-1 associates with the middle part of intracytoplasmic region of IL-21R and enhances the maturation of IL-21R from N-linked glycosylated form to fully glycosylated mature form.	Nitrogen	118-119	WD repeat and SOCS box containing 1	Homo sapiens	0-5
17520925-1	2007	Estuaries have been suggested to have an important role in reducing the nitrogen load transported to the sea.	Nitrogen	72-80	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	105-108
17520925-7	2007	In the estuary bay with a long residence time, in the Archipelago Sea, up to 4.5% of nitrate loading and 19% of nitrogen loading were removed before entering the sea.	Nitrogen	112-120	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	66-69
17520925-8	2007	According to our results, the sediments of the fast-flowing rivers and the estuary areas with short residence times have a limited capacity to reduce the nitrogen load to the Baltic Sea.	Nitrogen	154-162	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	182-185
17355433-9	2007	In the nla mutant, the deletion of the RING domain from NLA altered its subcellular localization, disrupted the interaction between NLA and AtUBC8 and caused the early senescence phenotype induced by low inorganic nitrogen.	Nitrogen	214-222	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	7-10
17355433-9	2007	In the nla mutant, the deletion of the RING domain from NLA altered its subcellular localization, disrupted the interaction between NLA and AtUBC8 and caused the early senescence phenotype induced by low inorganic nitrogen.	Nitrogen	214-222	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	56-59
17355433-10	2007	All the results indicate that NLA is a positive regulator for the development of the adaptability of Arabidopsis to nitrogen limitation.	Nitrogen	116-124	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	30-33
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	133-137
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	allantoate permease	Saccharomyces cerevisiae S288C	155-159
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	allantoate permease	Saccharomyces cerevisiae S288C	173-177
35133011-5	2022	We show that OsEIL1 in rice plays a contrasting role to Arabidopsis-homologous ETHYLENE-INSENSITIVE3 (AtEIN3) and maintains rice growth under NH4 + by stabilizing protein N-glycosylation and reducing root NH4 + efflux.	Nitrogen	171-172	Ethylene insensitive 3 family protein	Arabidopsis thaliana	79-100
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	211-216
20974806-3	2011	Here, we demonstrate for the first time that binding of the nitrogen catabolite repression-responsive GATA transcription activators (Gln3 and Gat1) to the DAL5 promoter and DAL5 expression require Pph21/22-Tpd3-Cdc55/Rts1 in rapamycin-treated glutamine-grown cells.	Nitrogen	60-68	protein phosphatase 2A regulatory subunit RTS1	Saccharomyces cerevisiae S288C	217-221
17263732-10	2007	Loss of glycosylation at N65 resulted in aggregation of protein O-fucosyltransferase 1, suggesting that N-glycosylation at this site is essential for proper folding of the enzyme.	Nitrogen	25-26	protein O-fucosyltransferase 1	Bos taurus	56-86
35455946-9	2022	N-glycosylation modification, plasma membrane localization, and ER stress resulted from the accumulation of mutant protein in ER, as shown by the higher expression of GRP78 and p-IRE1alpha.	Nitrogen	0-1	endoplasmic reticulum to nucleus signaling 1	Homo sapiens	179-188
17257170-4	2007	As a sequel to earlier investigations related to PEPC phosphorylation in N(2)-fixing nodules of Glycine max, we now present a detailed molecular analysis of the PpcK multigene family in nodulated soybeans.	Nitrogen	73-77	phosphoenolpyruvate carboxylase, housekeeping isozyme	Glycine max	49-53
21818298-2	2011	In general, mature APP (mAPP, N- and O-glycosylated form) is subject to successive cleavages by alpha- or beta-, and gamma-secretases in the late protein secretory pathway and/or at plasma membrane, while immature APP (imAPP, N-glycosylated form) locates in the early secretory pathway such as endoplasmic reticulum or cis-Golgi, in which imAPP is not subject to metabolic cleavages.	Nitrogen	226-227	amyloid beta (A4) precursor protein	Mus musculus	24-28
35344324-0	2022	Temperature-Dependent n-p-n Switching and Highly Selective Room-Temperature n-SnSe2/p-SnO/n-SnSe Heterojunction-Based NO2 Gas Sensor.	Nitrogen	90-92	strawberry notch homolog 1	Homo sapiens	86-89
21082772-2	2010	Linear hydroformylation of N-protected allyl- or homoallylamines (cyclohydrocarbonylation: CHC), followed by a reductive amination constitute the two key steps toward convenient routes to aza-heterocycles.	Nitrogen	27-28	clathrin heavy chain	Homo sapiens	91-94
17319845-12	2007	When alanine was supplied as the nitrogen source, alaat1-1 plants utilized alanine less efficiently than wild-type plants did.	Nitrogen	33-41	alanine aminotransferas	Arabidopsis thaliana	50-56
34999400-10	2022	Multi-linear regression analysis indicated that nitrogen release was closely related to biochar nitrogen content, pH and average pore width.	Nitrogen	48-56	phenylalanine hydroxylase	Homo sapiens	114-116
17846567-3	2007	The detection of the low energy conformation of O=C-N-phenethyl segment in solution allowed the correlation of the NMR data with the configuration of newly stereogenic carbon C-2; thus, one diastereomer was labeled SS while the other was RS.	Nitrogen	52-53	complement C2	Homo sapiens	175-178
20942445-0	2010	The reactivity of phosphagermaallene Tip(t-Bu)Ge=C=PMes* with doubly and triply bonded nitrogen compounds.	Nitrogen	87-95	TOR signaling pathway regulator	Homo sapiens	37-40
35294933-2	2022	In this work, using first-principles calculations and a particle swarm optimization structural search method, four novel nitrogen-rich structures are predicted at high pressures, i.e., two ZnN3 phases with the same space group P-1 (low-pressure phase LP-ZnN3 and high-pressure phase HP-ZnN3), Cmm2-ZnN5 and Pcc2-ZnN6 , the energy density are estimated to be 1.41 kJ/g, 1.88 kJ/g, 4.07 kJ/g, and 2.60 kJ/g, respectively.	Nitrogen	121-129	crystallin gamma D	Homo sapiens	307-310
20880010-5	2010	As revealed by treatments with carbohydrate-digesting enzymes, both GC-A and GC-B are hyperglycosylated at N-linked glycosylation sites in the developing brain.	Nitrogen	107-108	natriuretic peptide receptor 2	Rattus norvegicus	77-81
20615392-0	2010	Main contribution of the cytochrome P450 isoenzyme 1A2 (CYP1A2) to N-demethylation and 5-sulfoxidation of the phenothiazine neuroleptic chlorpromazine in human liver--A comparison with other phenothiazines.	Nitrogen	67-68	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	25-54
20615392-0	2010	Main contribution of the cytochrome P450 isoenzyme 1A2 (CYP1A2) to N-demethylation and 5-sulfoxidation of the phenothiazine neuroleptic chlorpromazine in human liver--A comparison with other phenothiazines.	Nitrogen	67-68	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	56-62
20828702-3	2010	Based on the chromatographic behaviors for the resolution of PPI analogues on CSP 1, a chiral recognition mechanism utilizing the sulfoxide oxygen and the benzimidazole ring nitrogen of PPIs as bidentate coordination donors to form an enantioselective ternary complex with the central Cu(II) ion and the chiral stationary bidentate ligand was proposed.	Nitrogen	174-182	regulator of calcineurin 1	Homo sapiens	78-83
17254574-0	2007	Urmylation controls Nil1p and Gln3p-dependent expression of nitrogen-catabolite repressed genes in Saccharomyces cerevisiae.	Nitrogen	60-68	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	30-35
17254574-2	2007	Here is shown that the lack of urmylation causes derepression of the GAP1 gene (encoding a nitrogen-regulated broad-spectrum amino acid-scavenging permease) in the presence of rich nitrogen sources, and simultaneous inhibition of the expression of CIT2, a TCA-cycle gene involved in the production of glutamate and glutamine.	Nitrogen	91-99	citrate (Si)-synthase CIT2	Saccharomyces cerevisiae S288C	248-252
17174270-5	2007	Ovine milk PrP(C) is mainly present as three species that differ in the extent of their N-linked glycosylation, with glycoform profiles varying among animals.	Nitrogen	88-89	major prion protein	Ovis aries	11-17
17189489-9	2007	First, QDR2 transcription is activated under nitrogen (NH(4)(+)) limitation or when the auxotrophic strain examined enters stationary phase due to leucine limitation, this regulation being dependent on general amino acid control by Gcn4p.	Nitrogen	45-53	cation transporter	Saccharomyces cerevisiae S288C	7-11
35294933-5	2022	In Cmm2-ZnN5 and Pcc2-ZnN6, nitrogen atoms polymerize into three-dimensional network structures and network layers under high pressures.	Nitrogen	28-36	crystallin gamma D	Homo sapiens	17-20
20817882-7	2010	Recent seasonal H1N1 viruses expressed three to four N-glycosylation sequons on the head of hemagglutinin and were very sensitive to inhibition by SP-D or MBL, whereas A(H1N1) pandemic viruses expressed a single N-glycosylation sequon and were resistant to either collectin.	Nitrogen	18-19	mannose binding lectin 2	Homo sapiens	155-158
35123998-9	2022	SIGNIFICANCE: The findings of the present study demonstrate that nesfatin-1 treatment provides neuroprotection against seizure-induced oxidative damage and memory dysfunction by inhibiting reactive nitrogen species and upregulating antioxidant capacity, indicating its potential in alleviating memory deficits and increasing the effectiveness of conventional anti-convulsant therapies.	Nitrogen	198-206	nucleobindin 2	Rattus norvegicus	65-75
20817882-7	2010	Recent seasonal H1N1 viruses expressed three to four N-glycosylation sequons on the head of hemagglutinin and were very sensitive to inhibition by SP-D or MBL, whereas A(H1N1) pandemic viruses expressed a single N-glycosylation sequon and were resistant to either collectin.	Nitrogen	53-54	mannose binding lectin 2	Homo sapiens	155-158
35379968-3	2022	Our concept of oxidative onioation, where white phosphorus is selectively converted into triflate salts of versatile P1 transfer reagents such as (P(LN)3)(OTf)3 (LN is a cationic, N-based substituent; that is, 4-dimethylaminopyridinio), provides a convenient alternative for the implementation of P-O, P-N and P-C bonds while circumventing the use of PCl3.	Nitrogen	180-181	PHD finger protein 19	Homo sapiens	351-355
20562849-3	2010	Quantitative proteomic analysis of N-glycosylated proteins detected an increased amount of CD90/THY1 in cancer supernatants compared with non-cancer supernatants.	Nitrogen	35-36	Thy-1 cell surface antigen	Homo sapiens	91-95
20562849-3	2010	Quantitative proteomic analysis of N-glycosylated proteins detected an increased amount of CD90/THY1 in cancer supernatants compared with non-cancer supernatants.	Nitrogen	35-36	Thy-1 cell surface antigen	Homo sapiens	96-100
35379968-3	2022	Our concept of oxidative onioation, where white phosphorus is selectively converted into triflate salts of versatile P1 transfer reagents such as (P(LN)3)(OTf)3 (LN is a cationic, N-based substituent; that is, 4-dimethylaminopyridinio), provides a convenient alternative for the implementation of P-O, P-N and P-C bonds while circumventing the use of PCl3.	Nitrogen	304-305	PHD finger protein 19	Homo sapiens	351-355
20723225-2	2010	Glutamine synthetase (GS), occupies a central position in nitrogen assimilation and recycling, justifying the extensive number of studies that have been dedicated to this enzyme from several plant sources.	Nitrogen	58-66	LOC11405318	Medicago truncatula	0-20
35454076-9	2022	We tested a small biological molecule, Tunicamycin, that blocks a specific step of the protein N-glycosylation pathway in the endoplasmic reticulum (ER), i.e., the catalytic activity of N-acetylglusosaminyl 1-phosphate transferase (GPT).	Nitrogen	95-96	glutamic--pyruvic transaminase	Homo sapiens	232-235
20571546-2	2010	We genetically introduced an additional N-glycosylation sequon into HEXA, which caused amino acid substitutions (S51 to N and A53 to T) at homologous positions to N84 and T86 in the beta-subunit.	Nitrogen	40-41	hexosaminidase subunit alpha	Homo sapiens	68-72
35301431-0	2022	Hypoxia-induced GLT8D1 promotes glioma stem cell maintenance by inhibiting CD133 degradation through N-linked glycosylation.	Nitrogen	101-102	glycosyltransferase 8 domain containing 1	Mus musculus	16-22
20439465-6	2010	N-Glycosylation of gp120 varied, depending on the cell type used for its expression and the metabolic manipulation during expression.	Nitrogen	0-1	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	19-24
35301431-6	2022	We reveal that GLT8D1 impedes CD133 degradation through the endosomal-lysosomal pathway by N-linked glycosylation and protein-protein interaction.	Nitrogen	91-92	glycosyltransferase 8 domain containing 1	Mus musculus	15-21
35258231-9	2022	The total N2 emissions ranged from 0.70-1.82 kg hm-2.	Nitrogen	10-12	cholinergic receptor muscarinic 2	Homo sapiens	48-52
20482580-1	2010	Nitrogen (N) effects on ecosystem carbon (C) budgets are critical to understand as C sequestration is considered as a mechanism to offset anthropogenic CO(2) emissions.	Nitrogen	0-8	steroid sulfatase	Homo sapiens	80-84
34981854-3	2022	Here, we investigated the role of N-linked glycosylation on the processing and function of FGFR4.	Nitrogen	34-35	fibroblast growth factor receptor 4	Homo sapiens	91-96
20199623-3	2010	Metabolite profiling by gas chromatography-time of flight-mass spectrometry (GC-TOF-MS) and high-performance liquid chromatography (HPLC) revealed that loss of cICDH function produced only small effects on leaf compounds involved in carbon and nitrogen assimilation.	Nitrogen	244-252	cytosolic NADP+-dependent isocitrate dehydrogenase	Arabidopsis thaliana	160-165
35297184-2	2022	Herein, Hemin (Fe (III)-protoporphyrin IX) is introduced into the nitrogen-doped reduced graphene oxide (N-rGO) to obtain a novel sensing material HNG-ethanol.	Nitrogen	66-74	neurogranin	Homo sapiens	147-150
20799608-5	2010	It is believed that one of the main causes of an increase of resistance of the rat organism to nitrogen anesthesia after seances of the many-day interval 6% hypoxia is accumulation of HSP-70 in brain motor cortex cells.	Nitrogen	95-103	heat shock protein family A (Hsp70) member 1B	Rattus norvegicus	184-190
35524531-8	2022	According to the binary quadratic regression fitting equation, when the potential maximum yield reached 2749 kg hm-2 in wet year, nitrogen application depth was 22.7 cm, and nitrogen application rate was 245 kg hm-2.	Nitrogen	130-138	cholinergic receptor muscarinic 2	Homo sapiens	112-116
20541250-5	2010	N-glycosylation of the V0a1 subunit, essential for its efficient ER-to-lysosome delivery, requires the selective binding of PS1 holoprotein to the unglycosylated subunit and the Sec61alpha/oligosaccharyltransferase complex.	Nitrogen	0-1	presenilin 1	Mus musculus	124-127
20496895-0	2010	Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies.	Nitrogen	9-10	metallothionein 2A	Homo sapiens	26-31
20496895-0	2010	Multiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies.	Nitrogen	9-10	melanocortin 1 receptor	Homo sapiens	92-97
20378536-10	2010	Nuclear Gln3 localization in proline-grown (nitrogen limited) cells exhibits no requirement for Pph21/22-Tpd3/Cdc55, whereas nuclear Gat1 localization under these conditions is absolutely dependent on Pph21/22-Tpd3/Cdc55.	Nitrogen	44-52	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	8-12
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	271-279	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	47-52
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	271-279	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	173-178
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	296-304	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	47-52
20378536-11	2010	Furthermore, the extent to which Pph21/22-Tpd3-Cdc55 is required for the TorC1 pathway (Rap) to induce nuclear Gat1 localization is regulated in parallel with Pph21/22-Tpd3-Cdc55-dependent Gln3 dephosphorylation and NCR-sensitive transcription, being highest in limiting nitrogen and lowest when nitrogen is in excess.	Nitrogen	296-304	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	173-178
35524531-8	2022	According to the binary quadratic regression fitting equation, when the potential maximum yield reached 2749 kg hm-2 in wet year, nitrogen application depth was 22.7 cm, and nitrogen application rate was 245 kg hm-2.	Nitrogen	174-182	cholinergic receptor muscarinic 2	Homo sapiens	112-116
35524531-8	2022	According to the binary quadratic regression fitting equation, when the potential maximum yield reached 2749 kg hm-2 in wet year, nitrogen application depth was 22.7 cm, and nitrogen application rate was 245 kg hm-2.	Nitrogen	174-182	cholinergic receptor muscarinic 2	Homo sapiens	211-215
35524531-9	2022	When the maximum potential yield reached 2596 kg hm-2 in normal year, nitrogen application depth was 20.6 cm, and nitrogen application rate was 235 kg hm-2.	Nitrogen	70-78	cholinergic receptor muscarinic 2	Homo sapiens	49-53
20354865-10	2010	Our results suggest that N-linked glycosylation of DPP10 plays an important role in modulating Kv4 channel activities.	Nitrogen	25-26	inactive dipeptidyl peptidase 10	Cricetulus griseus	51-56
35524531-9	2022	When the maximum potential yield reached 2596 kg hm-2 in normal year, nitrogen application depth was 20.6 cm, and nitrogen application rate was 235 kg hm-2.	Nitrogen	114-122	cholinergic receptor muscarinic 2	Homo sapiens	49-53
35524531-9	2022	When the maximum potential yield reached 2596 kg hm-2 in normal year, nitrogen application depth was 20.6 cm, and nitrogen application rate was 235 kg hm-2.	Nitrogen	114-122	cholinergic receptor muscarinic 2	Homo sapiens	151-155
20303774-5	2010	Activities of several enzymes involved in nitrogen and carbon metabolism including nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase (NADH-GOGAT), NADP-dependent isocitrate dehydrogenase (NADP-ICDH), and phosphoenol pyruvate carboxylase (PEPCase) were regulated by GABA in the growth medium.	Nitrogen	42-50	isocitrate dehydrogenase	Arabidopsis thaliana	213-217
35524531-10	2022	Integrating the effects of nitrogen application rate and depth on yield, biomass and agronomic efficiency of nitrogen fertilizer, and farmer"s fertilizer application habits, the recommended nitrogen application depth was 20-23 cm, and nitrogen application amount was 120-150 kg hm-2, which could further improve water productivity and nitrogen use efficiency of spring wheat in arid areas of central Gansu Province.	Nitrogen	190-198	cholinergic receptor muscarinic 2	Homo sapiens	278-282
20233714-3	2010	TOR senses nitrogen availability and regulates transcription factors such as Gln3p.	Nitrogen	11-19	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	77-82
35270425-5	2022	With the increase of N, AOA abundance decreased in a regular trend from 4.88 x 107 to 1.05 x 107 copies g-1 dry soil, while AOB abundance increased from 3.63 x 107 up to a maximum of 8.24 x 107 copies g-1 dry soil with the N105 treatment (105 kg N ha-1 yr-1).	Nitrogen	21-22	solute carrier family 9 member B1	Homo sapiens	246-257
20233714-7	2010	In addition to inducing amino acid biosynthetic genes, Gcn4p in conjunction with Gln3p activates genes required for the assimilation of secondary nitrogen sources such as gamma-aminobutyric acid (GABA).	Nitrogen	146-154	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	81-86
20397810-9	2010	IS-SCGB1A1/IL8 levels were also inversely associated with nitrogen slope [r = -0.52, p &lt; 0.001] and HRCT SA score [r = -0.51, p &lt; 0.001].	Nitrogen	58-66	secretoglobin family 1A member 1	Homo sapiens	3-10
35558187-2	2022	An increased blood urea nitrogen to albumin ratio (BAR) has previously been shown to be a valuable biomarker with predictive utility in several diseases.	Nitrogen	24-32	bifunctional apoptosis regulator	Homo sapiens	51-54
19697054-7	2010	The T/N ratio of TS in patients that died of disease was significantly higher than in patients with free of disease, whereas there were no relationships between The T/N ratio of DPD and disease status.	Nitrogen	6-7	thymidylate synthetase	Homo sapiens	17-19
20154027-0	2010	Npr2, yeast homolog of the human tumor suppressor NPRL2, is a target of Grr1 required for adaptation to growth on diverse nitrogen sources.	Nitrogen	122-130	NPR2 like, GATOR1 complex subunit	Homo sapiens	50-55
34999438-5	2022	Intermittent and continuous aeration could both effectively remove total nitrogen (TN) and NH4+-N with removal efficiencies above 64% in the leachate.	Nitrogen	73-81	C-type lectin domain family 3 member B	Homo sapiens	83-85
20209506-3	2010	The glycopeptide analysis workflow was applied to human beta2-glycoprotein I (beta2-GPI, apolipoprotein H), which contains multiple N-glycosylation sites.	Nitrogen	132-133	apolipoprotein H	Homo sapiens	56-76
20209506-3	2010	The glycopeptide analysis workflow was applied to human beta2-glycoprotein I (beta2-GPI, apolipoprotein H), which contains multiple N-glycosylation sites.	Nitrogen	132-133	apolipoprotein H	Homo sapiens	78-87
20209506-3	2010	The glycopeptide analysis workflow was applied to human beta2-glycoprotein I (beta2-GPI, apolipoprotein H), which contains multiple N-glycosylation sites.	Nitrogen	132-133	apolipoprotein H	Homo sapiens	89-105
35094035-8	2022	In the series PEN, 6,13-DAP, and TAP, the alpha-band (S0   S2 transition) gains significantly in intensity due to individual effects of the introduced nitrogen atoms on the orbital energies.	Nitrogen	151-159	death associated protein	Homo sapiens	24-27
19862687-4	2010	Previously, N-[(18)F]fluoroethylpiperidin-4ylmethyl acetate ([(18)F]FEP-4MA) showed that the (18)F-labeled analog of MP4A possessed desirable properties for the quantification of cerebral AChE activity by PET.	Nitrogen	12-16	acetylcholinesterase	Rattus norvegicus	188-192
20007973-7	2010	Interestingly, EFR(N143Q) lacking a single conserved N-glycosylation site from the EFR ectodomain accumulated to reduced levels and lost the ability to bind its ligand and to mediate elf18-elicited oxidative burst.	Nitrogen	19-20	EF-TU receptor	Arabidopsis thaliana	15-18
20007973-7	2010	Interestingly, EFR(N143Q) lacking a single conserved N-glycosylation site from the EFR ectodomain accumulated to reduced levels and lost the ability to bind its ligand and to mediate elf18-elicited oxidative burst.	Nitrogen	19-20	EF-TU receptor	Arabidopsis thaliana	83-86
17121835-6	2007	The structure of the inactivated enzyme shows covalent modification of the Pro-1 nitrogen atom by (R)-2-hydroxypropanoate at the C3 position.	Nitrogen	81-89	lamin A/C	Homo sapiens	75-80
16427276-3	2007	Bin 1 containing larger amount of swine manure and less amount of rice straw showed a higher nitrogen loss (8%), shorter thermophilic phase, and longer maturity time (about 2 weeks) than bin 2.	Nitrogen	93-101	bridging integrator 1	Sus scrofa	0-5
35211008-0	2021	Stachytine Hydrochloride Improves Cardiac Function in Mice with ISO-Induced Heart Failure by Inhibiting the alpha-1,6-Fucosylation on N-Glycosylation of beta1AR.	Nitrogen	134-135	adenosine A1 receptor	Mus musculus	153-160
17352678-4	2007	DPP-IV inhibitors related to the xanthines include purine analogues with other arrangements of the nitrogen atoms in the core structure, imidazoles, uracils, pyrimidines, pyridines, and some fused pyridines.	Nitrogen	99-107	dipeptidyl peptidase 4	Homo sapiens	0-6
20030721-1	2010	We demonstrated that a yeast deletion mutant in IPT1 and SKN1, encoding proteins involved in the biosynthesis of mannosyldiinositolphosphoryl ceramides, is characterized by increased autophagy and DNA fragmentation upon nitrogen (N) starvation as compared with the single deletion mutants or wild type (WT).	Nitrogen	220-228	beta-glucan synthesis-associated protein SKN1	Saccharomyces cerevisiae S288C	57-61
35211008-11	2021	The N-glycosylation of beta1 adrenergic receptors decreased after continuous isoproterenol stimulation, while stachytine hydrochloride can increase the N-glycosylation of beta1AR in the heart of mice with isoproterenol-induced heart failure.	Nitrogen	152-153	adenosine A1 receptor	Mus musculus	171-178
20002318-1	2010	Experimental evidence demonstrates a higher efficiency of water and nitrogen use in C(4) compared with C(3) plants, which is hypothesized to drive differences in biomass allocation between C(3) and C(4) species.	Nitrogen	68-76	complement C4A (Rodgers blood group)	Homo sapiens	84-88
20002318-1	2010	Experimental evidence demonstrates a higher efficiency of water and nitrogen use in C(4) compared with C(3) plants, which is hypothesized to drive differences in biomass allocation between C(3) and C(4) species.	Nitrogen	68-76	complement C4A (Rodgers blood group)	Homo sapiens	198-202
20002318-5	2010	Photosynthesis and nitrogen-use efficiency were also greater in C(4) species, varying markedly between clades.	Nitrogen	19-27	complement C4A (Rodgers blood group)	Homo sapiens	64-68
19874874-3	2010	The results show that the highly selective GnRH agonist (i.e., [Des-Gly(10),d-His(Bzl)(6),Pro-NHEt(9)]-LHRH; Histrelin) stimulates the secretion of OT from an isolated rat H-N system.	Nitrogen	94-95	gonadotropin releasing hormone 1	Rattus norvegicus	43-47
19915009-2	2010	The interleukin-6 signal transducer glycoprotein 130 (gp130) is a common co-receptor for cytokines of the interleukin (IL)-6 family and is N-glycosylated at 9 of 11 potential sites.	Nitrogen	139-140	interleukin 6 cytokine family signal transducer	Homo sapiens	54-59
19915009-3	2010	Whereas N-glycosylation of the extracellular domains D1-D3 of gp130 has been shown to be dispensable for binding of the gp130 ligand IL-6 and its cognate receptor in vitro, the role of the N-linked glycans on domains D4 and D6 is still unclear.	Nitrogen	8-9	interleukin 6 cytokine family signal transducer	Homo sapiens	62-67
17178884-0	2006	N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.	Nitrogen	0-1	interleukin 24	Homo sapiens	19-24
17178884-0	2006	N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.	Nitrogen	0-1	interleukin 24	Homo sapiens	25-30
17178884-4	2006	An adenovirus vector expressing a nonsecreted and nonglycosylated version of MDA-7/IL-24 protein was generated via deletion of its signal peptide and point mutations of its three N-glycosylated sites.	Nitrogen	179-180	interleukin 24	Homo sapiens	77-82
17178884-4	2006	An adenovirus vector expressing a nonsecreted and nonglycosylated version of MDA-7/IL-24 protein was generated via deletion of its signal peptide and point mutations of its three N-glycosylated sites.	Nitrogen	179-180	interleukin 24	Homo sapiens	83-88
17030562-9	2006	The N-9-based film decreased intracellular IL-1RA (P &lt; 0.05), which has anti-inflammatory intracrine functions.	Nitrogen	4-5	interleukin 1 receptor antagonist	Homo sapiens	43-49
17046716-6	2006	A mutant AcFGF possessing two N-linked glycosylation sites was secreted into the medium more abundantly than that which occurred for wt AcFGF.	Nitrogen	30-31	fibroblast growth factor	Autographa californica nucleopolyhedrovirus	9-14
17050773-11	2006	Quantitative analysis of N-linked glycosylation of IgA heavy chains showed significant differences in glycan composition between mIgA and pIgA, including the presence of oligomannose exclusively on pIgA.	Nitrogen	25-26	phosphatidylinositol glycan anchor biosynthesis class A	Homo sapiens	138-142
17238830-5	2006	Cation exchange purification results in the isolation of at least two N-linked glycosylated IL-24 dimers covalently associated via intermolecular disulfide bonds.	Nitrogen	70-71	interleukin 24	Homo sapiens	92-97
17238830-6	2006	These molecularly defined N-glycosylated IL-24 dimers elicited dose-dependent secretion of tumor necrosis factor-alpha (TNF-alpha) and IL-6 from human monocytes, as well as cytotoxicity to human melanoma cell lines.	Nitrogen	26-27	interleukin 24	Homo sapiens	41-46
17011210-0	2006	Secretory expression of synthetic human Fas ligand extracellular domain gene in Pichia pastoris: influences of tag addition and N-glycosylation site deletion, and development of a purification method.	Nitrogen	128-129	Fas ligand	Homo sapiens	40-50
16990280-5	2006	When NPN was overexpressed in cell culture, the protein was detected in the cultured medium, and upon treatment with N-glycosidase F, the molecular mass was lowered by approximately 14 kDa, indicating that NPN is a secreted N-glycosylated protein.	Nitrogen	5-6	nephrocan	Mus musculus	206-209
16959783-3	2006	In this study, we investigated in HEK293 cells the intracellular localization and N-glycosylation of the ABCA3 mutants so far identified in fatal surfactant deficiency patients.	Nitrogen	82-83	ATP binding cassette subfamily A member 3	Homo sapiens	105-110
16959765-4	2006	Importantly, the absence of N-glycosylation sites (sites 1-5) on the beta-propeller resulted in the persistent association of integrin subunit with calnexin in the endoplasmic reticulum, which subsequently blocked heterodimerization and its expression on the cell surface.	Nitrogen	28-29	calnexin	Bos taurus	148-156
16942742-5	2006	P-gp substrates and inhibitors significantly increased intracellular calcein fluorescence in freshly isolated suspended PBCEC and in suspended PBCECs after storage in liquid nitrogen.	Nitrogen	174-182	phosphoglycolate phosphatase	Homo sapiens	0-4
16981026-5	2006	An X-ray crystal structure determination showed eta1-coordination of the tetrazolato ligand through the 2-nitrogen atom.	Nitrogen	106-114	secreted phosphoprotein 1	Homo sapiens	48-52
16738006-5	2006	Enzymatic removal of N-linked glycosylations from the beta1-subunit resulted in a single band that migrated at a lower molecular mass than the native beta1-subunit bands, suggesting that the native beta1-subunit exists in either a core glycosylated or highly glycosylated form.	Nitrogen	21-22	hemoglobin, beta adult major chain	Mus musculus	54-59
16762980-8	2006	The Ce-T-synthase has four potential N-glycosylation sequons, whereas the mammalian orthologs lack N-glycosylation sequons.	Nitrogen	37-38	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Homo sapiens	7-17
16864574-0	2006	Transduction of the nitrogen signal activating Gln3-mediated transcription is independent of Npr1 kinase and Rsp5-Bul1/2 ubiquitin ligase in Saccharomyces cerevisiae.	Nitrogen	20-28	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	47-51
16864574-0	2006	Transduction of the nitrogen signal activating Gln3-mediated transcription is independent of Npr1 kinase and Rsp5-Bul1/2 ubiquitin ligase in Saccharomyces cerevisiae.	Nitrogen	20-28	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	109-118
16864574-2	2006	In cells using ammonium or glutamine, the GATA transcription factor Gln3 is sequestered in the cytoplasm by Ure2 whereas it enters the nucleus after a shift to a nonpreferred nitrogen source like proline or upon addition of rapamycin, the TOR complex inhibitor.	Nitrogen	175-183	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	68-72
16864574-6	2006	The derepression of Gln3-activated genes in ammonium-grown npr1 cells results from the reduced uptake of the nitrogen-repressing compound because NCR could be restored in npr1 cells by repairing ammonium-uptake defects through different means.	Nitrogen	109-117	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	20-24
16981706-1	2006	All known guanidino kinases contain a conserved cysteine residue that interacts with the non-nucleophilic eta1-nitrogen of the guanidino substrate.	Nitrogen	111-119	secreted phosphoprotein 1	Homo sapiens	106-110
16961344-1	2006	The diffusion reaction of TBA2Cu(II)Cl4 (TBA = tetrabutylammonium) and a N-containing organic donor, BP-TTF [=bis(pyrazino)tetrathiafulvalene], yielded a 3-D supramolecular Cu complex, [CuCl2(BP-TTF)] (1).	Nitrogen	73-74	ras homolog family member H	Homo sapiens	104-107
16784820-4	2006	We have demonstrated that N/OFQ-induced activation of the HPA axis is mediated via the central N/OFQ peptide receptor (NOP) using the recently described selective NOP antagonist [Nphe(1),Arg(14),Lys(15)]nociceptin/orphanin FQ-NH(2) (UFP-101).	Nitrogen	26-27	prepronociceptin	Rattus norvegicus	203-213
16784820-4	2006	We have demonstrated that N/OFQ-induced activation of the HPA axis is mediated via the central N/OFQ peptide receptor (NOP) using the recently described selective NOP antagonist [Nphe(1),Arg(14),Lys(15)]nociceptin/orphanin FQ-NH(2) (UFP-101).	Nitrogen	26-27	prepronociceptin	Rattus norvegicus	214-225
19372833-4	2006	Prolonged exposure to carbohydrate-binding agents slowly and progressively selects for deletions of glycans at N-glycosylation sites in HIV gp120.	Nitrogen	111-112	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	140-145
16911515-5	2006	Analysis of nitrogen-source-dependent transcript profiles via microarray analysis of glucose-limited, aerobic chemostat cultures revealed a common upregulation of PDR12 in cultures grown with leucine, methionine or phenylalanine as sole nitrogen source.	Nitrogen	12-20	ATP-binding cassette multidrug transporter PDR12	Saccharomyces cerevisiae S288C	163-168
16911515-5	2006	Analysis of nitrogen-source-dependent transcript profiles via microarray analysis of glucose-limited, aerobic chemostat cultures revealed a common upregulation of PDR12 in cultures grown with leucine, methionine or phenylalanine as sole nitrogen source.	Nitrogen	237-245	ATP-binding cassette multidrug transporter PDR12	Saccharomyces cerevisiae S288C	163-168
16928112-3	2006	All complexes are found to be bound to the nitrogen end of the HCN molecule and on the "atop site" of the copper cluster.	Nitrogen	43-51	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	63-66
21170291-4	2010	MiR-21 can be induced in neurons by prolonged N-methyl-D-aspartic acid receptor stimulation, an excitotoxic process active in HIV and other neurodegenerative diseases.	Nitrogen	46-48	microRNA 21	Homo sapiens	0-6
35155954-8	2022	In contrast, with a 15N value between -3.6 and 0%, N2 accounts for over 70% of SG in wells TM1 and CD1, respectively, indicating the atmosphere, the ammonification of OM, and the presence of poor preservation conditions due to a high level of connectivity between the shale bed and the atmosphere acted as the sources of N2.	Nitrogen	51-53	CD1c molecule	Homo sapiens	99-102
20302089-5	2010	The results of experiments and calculations suggest that the silver atom prefers to be bound to N and S atoms in the aromatic ring, and thus two different complexes are formed, i.e., conformer N-Ag and conformer S-Ag.	Nitrogen	96-97	S-antigen visual arrestin	Homo sapiens	212-216
16838277-5	2006	Although MICL was highly N-glycosylated in primary cells, the level of glycosylation was found to vary between cell types.	Nitrogen	25-26	C-type lectin domain family 12 member A	Homo sapiens	9-13
16721869-3	2006	In 1, the Cd1, Cd3, and Cd4 atoms are all pentacoordinate, while the Cd2 atom is coordinated by four oxygen atoms from three phosphonate ligands and two nitrogen atoms from the chelating phen in a distorted octahedral geometry.	Nitrogen	153-161	CD2 molecule	Homo sapiens	69-72
35022194-4	2022	METHODS: We examined the contribution of immunosuppressive myeloid cells expressing arginase 1 and nitric oxide synthase 2 in building up a reactive nitrogen species (RNS)-dependent chemical barrier and shaping the PDAC immune landscape.	Nitrogen	149-157	arginase 1	Homo sapiens	84-94
16808534-2	2006	The diastereoselection is dependent on the temperature of the reaction and the structure of the substituent at C-2 and can be rationalized by accepting a 1,4-asymmetric induction process after coordination of the selenium to the nitrogen atom of the allylamine system.	Nitrogen	229-237	complement C2	Homo sapiens	111-114
19836948-2	2009	Adducts were formed by N-alkylation of the Pro-1 at the catalytic site with a loss of an amino group of the inhibitor.	Nitrogen	23-24	lamin A/C	Homo sapiens	43-48
35050863-4	2022	The load of total nitrogen (TN) and total phosphorus (TP) of NPS from different pollution sources including farmland, decentralized livestock and poultry breeding and domestic pollution sources were estimated.	Nitrogen	18-26	C-type lectin domain family 3 member B	Homo sapiens	28-30
19893986-6	2009	Caspase-3 immunoreactivity in tracheal mucosa and in mixed glands was significantly decreased, in contrast to the control group and to cryopreserved tracheal segments in which it remained high, due to the effect of storage in liquid nitrogen (P &lt; 0.05, ANOVA and Tukey test).	Nitrogen	233-241	caspase 3	Canis lupus familiaris	0-9
16484342-8	2006	Finally, FUT1 and FUT2 were both found to direct alpha2-fucosylation on type 1 chains on both N- and O-linked structures.	Nitrogen	94-95	fucosyltransferase 1 (H blood group)	Homo sapiens	9-13
2684405-7	1989	Quantum mechanical calculations of the predicted ease of benzylic carbocation formation at C-1 and C-8 from the diol epoxides indicate that the 3,4-diol-1,2-epoxides should be less reactive due to resonance destabilization of the C-1 carbocation as a result of the electronegative nitrogen atom.	Nitrogen	281-289	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	91-102
16816182-0	2006	H-NS represses inv transcription in Yersinia enterocolitica through competition with RovA and interaction with YmoA.	Nitrogen	2-4	leishmanolysin like peptidase	Homo sapiens	15-18
16310944-3	2006	FT-IR of decomposition products of TNAZ revealed the evolution of oxides of nitrogen and HCN containing species suggesting the cleavage of C/N-NO(2) bond accompanied with the collapse of ring structure.	Nitrogen	36-37	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	89-92
16858123-3	2006	Of six cDNA-expressed rat P450 isoforms tested, CYP3A2 and CYP2C11 had high rates for N-debutlylation and 3"-hydroxylation of bupivacaine, respectively.	Nitrogen	9-10	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	59-66
16723486-6	2006	Treatment with the N-glycosylation inhibitor tunicamycin induces an epithelioid phenotype in clone-YH, like time in culture but disrupts the hTERT-RPE1 phenotype.	Nitrogen	19-20	telomerase reverse transcriptase	Homo sapiens	141-151
16713428-6	2006	At the 50 micromol/L uridine diphosphate glucoronic acid (UDPGA) concentration, UGT1A4 also catalyzed the N-glucuronidation of retigabine, the rates being approximately 5 and 6 pmol/(min.mg protein).	Nitrogen	106-107	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	80-86
16571673-11	2006	Therefore, our work demonstrates that AEX-3 regulates both RAB-3 and RAB-27, that both RAB-3 and RAB-27 regulate synaptic transmission, and that RAB-27 potentially acts through its effector RBF-1 to promote soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) function.	Nitrogen	215-216	MAP kinase-activating death domain protein	Caenorhabditis elegans	38-43
16817793-2	2006	However, the correlations of serum phosphorus level with OPN expression, and blood urea nitrogen (BUN) level with OPN expression in humans have not previously been reported.	Nitrogen	88-96	secreted phosphoprotein 1	Homo sapiens	114-117
16650003-5	2006	Nanoscale LC-MS(/MS) and MALDI-TOF(/TOF)-MS studies combined with enzymatic degradations showed that monomeric IPSE/alpha-1 contains two N-glycosylation sites, which are each occupied for a large proportion with core-difucosylated diantennary glycans that carry one or more Lewis X motifs.	Nitrogen	0-1	adrenoceptor alpha 1D	Homo sapiens	116-123
16413696-8	2006	Multivariate analysis confirms the significance of a PSA rise during the N-ADT period for CSS (p = 0.035) and OS (p = 0.038).	Nitrogen	73-74	kallikrein related peptidase 3	Homo sapiens	53-56
16516349-1	2006	The protein glutaminase has been traditionally considered as a mitochondrial enzyme, playing a key role in the energy and nitrogen metabolism of mammalian cells.	Nitrogen	122-130	glutaminase	Homo sapiens	12-23
16386315-4	2006	The Xenopus laevis MAP kinase phosphatase X17c gene and the Yeast nitrogen starvation-induced protein phosphatase Yvh1p gene were revealed to be highly homologous with Pyst2-L.	Nitrogen	66-74	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	114-119
16528036-4	2006	alpha-Glucosidase inhibitors derived from the glucose analogue deoxynojirimycin (DNJ) inhibit viral morphogenesis in cellulo via perturbation of the N-glycosylation pathway and hence the misfolding of viral glycoproteins that depend on certain N-glycans for correct folding.	Nitrogen	82-83	sucrase-isomaltase	Homo sapiens	0-17
16563360-5	2006	The anti-nociceptive effect of N/OFQ or EA was significantly blocked by intrathecal injection of [Nphe(1)]nociceptin(1-13)NH(2) (20 nmol), a selective antagonist of the NOP receptor, indicating the NOP-receptor-mediated mechanism.	Nitrogen	31-32	prepronociceptin	Rattus norvegicus	106-116
16487345-1	2006	Gln3 and Gat1/Nil1 are GATA-family transcription factors responsible for transcription of nitrogen-catabolic genes in Saccharomyces cerevisiae.	Nitrogen	90-98	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
16487345-5	2006	Gat1 and Gln3 localization are similar during steady-state growth, being cytoplasmic and nuclear with good and poor nitrogen sources, respectively.	Nitrogen	116-124	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	9-13
16802848-10	2006	Clearance is hepatic via N-oxidation by the hepatic cytochrome P450 (CYP) isoenzymes, CYP2C19, CYP2C9 and CYP3A4.	Nitrogen	25-26	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	95-101
16289480-3	2006	However, they showed only poor to moderate binding affinities, indicating that substitution of the C-4 pyrazole atom of the CB1 reference compound SR141716 by a nitrogen atom results in loss of affinity.	Nitrogen	161-169	complement component 4B (Chido blood group)	Mus musculus	99-102
16557496-3	2006	The experimental data demonstrated that the nitrogen bridge and the coordinated oxygen atom on the nitrogen bridge in the alkaloid compounds were the active sites in the MS2 fragmentations.	Nitrogen	44-52	MS2	Homo sapiens	170-173
16557496-3	2006	The experimental data demonstrated that the nitrogen bridge and the coordinated oxygen atom on the nitrogen bridge in the alkaloid compounds were the active sites in the MS2 fragmentations.	Nitrogen	99-107	MS2	Homo sapiens	170-173
16331329-6	2005	The LMCD1 protein was predicted by bioinformatics software to contain a novel cysteine-rich domain in the N-terminal region, two LIM domains in the C-terminal region, nine potential protein kinase C phosphorylation sites, seven casein kinase II phosphorylation sites, a tyrosine kinase phosphorylation site, seven N-glycosylation and N-myristoylation sites and a single potential N-glycosylation site, which is similar to the protein"s human counterpart.	Nitrogen	106-107	LIM and cysteine rich domains 1	Homo sapiens	4-9
16153830-1	2005	Potent and selective antagonists of the adenosine A2A receptor often contain a nitrogen-rich fused-ring heterocyclic core.	Nitrogen	79-87	adenosine A2a receptor	Homo sapiens	40-62
16179357-8	2005	The increased fiber yield was probably due to better photosynthetic performance and higher nitrogen assimilation rates observed in the AtNHX1-expressing cotton plants as compared with wild-type cotton plants under saline conditions.	Nitrogen	91-99	Na+/H+ exchanger 1	Arabidopsis thaliana	135-141
16014566-0	2005	The influence of N-linked glycosylation on the function of platelet glycoprotein VI.	Nitrogen	17-18	glycoprotein VI platelet	Homo sapiens	59-83
16014566-6	2005	These findings indicate that N-linked glycosylation at N92 in human GPVI is not required for surface expression, but contributes to maximal adhesion to type I collagen, CRP and, to a lesser extent, CVX.	Nitrogen	29-30	glycoprotein VI platelet	Homo sapiens	68-72
16202243-11	2005	Nitrogen starvation was also able to induce the synthesis of beta-galactosidase from the GGTII-lacZ fusiongene in a Pap1-dependent manner.	Nitrogen	0-8	regenerating family member 3 alpha	Homo sapiens	116-120
16853246-2	2005	The surface chemistry of carbon-nitrogen coupling is of fundamental importance to catalytic processes such as the industrial-scale synthesis of HCN from CH4 and NH3 over Pt.	Nitrogen	32-40	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	144-147
16124830-3	2005	This isoindoline binds to Cd2+ as a charge-neutral, zwitterionic, bidentate ligand using imine and pyridine nitrogen atoms to form the eight-coordinate fluxional complex, Cd(6"-MeLH)2(NO3)2.	Nitrogen	108-116	CD2 molecule	Homo sapiens	26-29
15831799-6	2005	It should be pointed out that the vasodilator response to ACh was restored in CH and CHT rats to the level obtained in N and NT rats, respectively, by an in vitro L-arginine addition.	Nitrogen	119-120	solute carrier family 5 member 7	Rattus norvegicus	85-88
16131661-7	2005	A single N-glycosylation site (Asn328-Cys- Thr) was identified by tryptic peptide mapping and de novo sequencing of native and PNGase A-deglycosylated CPO using matrix-assisted laser/desorption/ionization time-of-flight mass spectrometry (MALDI/TOF/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS).	Nitrogen	9-10	N-glycanase 1	Homo sapiens	127-133
15963593-0	2005	Characteristics of nitrogen release from synthetic zeolite Na-P1 occluding NH4NO3.	Nitrogen	19-27	TGF-beta activated kinase 1 (MAP3K7) binding protein 3	Homo sapiens	59-64
15823095-9	2005	Of the five members, only Lass2, Lass5 and Lass6 were N-glycosylated, each at their N-terminal Asn residue.	Nitrogen	54-55	ceramide synthase 2	Homo sapiens	26-31
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	agouti related neuropeptide	Rattus norvegicus	218-240
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	agouti related neuropeptide	Rattus norvegicus	242-246
15890775-6	2005	Incubation of hypothalamic explants with N/OFQ (1, 10, 100 nM) resulted in significant changes in CART and AgRP release.	Nitrogen	41-42	agouti related neuropeptide	Rattus norvegicus	107-111
16025565-0	2005	Human mitochondria-derived N-formylated peptides are novel agonists equally active on FPR and FPRL1, while Listeria monocytogenes-derived peptides preferentially activate FPR.	Nitrogen	27-28	formyl peptide receptor 2	Homo sapiens	94-99
15822115-11	2005	Compared to PAG-1 the number of potential N-glycosylation sites is lower in PAG-17 (three sites) and higher in PAG-6 and -7 (five and six sites, respectively).	Nitrogen	42-43	pregnancy-associated glycoprotein 6	Bos taurus	111-123
16040659-5	2005	Similar to plants missing ATG7, those missing ATG5 display early senescence and are hypersensitive to either nitrogen or carbon starvation, which is accompanied by a more rapid loss of organellar and cytoplasmic proteins.	Nitrogen	109-117	SAC domain-containing protein 8	Arabidopsis thaliana	46-50
15925632-2	2005	In addition, the effect of dissolved air on surface tension was studied at 150 degrees C by comparing dynamic surface tensions of air- or nitrogen-saturated AVR in contact with air or nitrogen.	Nitrogen	138-146	NLR family pyrin domain containing 6	Homo sapiens	157-160
16035799-0	2005	Rainbow scattering of CO and N2 from LiF(001).	Nitrogen	29-31	LIF interleukin 6 family cytokine	Homo sapiens	37-40
15933030-4	2005	Transcript level analysis revealed that among the five thiamine-pyrophospate-dependent decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3), only ARO10 was transcriptionally up-regulated when phenylalanine, leucine, or methionine was used as a nitrogen source compared to growth on ammonia, proline, and asparagine.	Nitrogen	242-250	branched-chain-2-oxoacid decarboxylase THI3	Saccharomyces cerevisiae S288C	132-136
15677381-1	2005	Rat endomannosidase is a glycosidic enzyme that catalyzes the cleavage of di-, tri-, or tetrasaccharides (Glc(1-3)Man), from N-glycosylation intermediates with terminal glucose residues.	Nitrogen	125-126	mannosidase endo-alpha	Homo sapiens	4-19
15781468-0	2005	Expression of four glutamine synthetase genes in the early stages of development of rainbow trout (Oncorhynchus mykiss) in relationship to nitrogen excretion.	Nitrogen	139-147	glutamine synthetase	Oncorhynchus mykiss	19-39
15781468-7	2005	We propose that the induction of glutamine synthetase genes early in development and the subsequent formation of the active protein are preparatory for the increased capacity of the embryo to convert the toxic nitrogen end product, ammonia, into glutamine, which may then be utilized in the ornithine-urea cycle or other pathways.	Nitrogen	210-218	glutamine synthetase	Oncorhynchus mykiss	33-53
15777625-2	2005	It has been previously reported that N-linked glycosylation is essential for the surface localization of CD39 and for its cellular activity.	Nitrogen	37-38	ectonucleoside triphosphate diphosphohydrolase 1	Homo sapiens	105-109
15777625-5	2005	The study has also shown that N-linked glycosylation of CD39 is dispensable for the activity after the protein is properly folded and targeted.	Nitrogen	30-31	ectonucleoside triphosphate diphosphohydrolase 1	Homo sapiens	56-60
15820896-4	2005	Each (py)2C(OEt)O- ion functions as an eta1:eta2:eta1:mu2 ligand in 1.0.5H2O chelating the two ZnII atoms through the 2-pyridyl nitrogen atoms and the common bridging, deprotonated oxygen atom; one asymmetric chelating nitrate completes six coordination at each metal center.	Nitrogen	128-136	secreted phosphoprotein 1	Homo sapiens	39-43
15716279-6	2005	Results of N-linked glycosylation-tagged full-length VKOR shows that the N terminus of VKOR is located in the endoplasmic reticulum lumen, and the C terminus is located in the cytoplasm.	Nitrogen	11-12	vitamin K epoxide reductase complex subunit 1	Homo sapiens	53-57
15716279-6	2005	Results of N-linked glycosylation-tagged full-length VKOR shows that the N terminus of VKOR is located in the endoplasmic reticulum lumen, and the C terminus is located in the cytoplasm.	Nitrogen	11-12	vitamin K epoxide reductase complex subunit 1	Homo sapiens	87-91
15537386-3	2005	Molecular cloning of cgl GnTI cDNA revealed a point mutation, which causes a critical amino acid substitution (Asp144--&gt;Asn), thereby creating an additional N-glycosylation site.	Nitrogen	32-33	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	25-29
15537386-4	2005	Heterologous expression of cgl GnTI in insect cells confirmed its lack of activity and the use of the N-glycosylation site.	Nitrogen	102-103	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	31-35
15794753-1	2005	Endo-beta-mannosidase is an endoglycosidase that hydrolyzes only the Man beta 1-4GlcNAc linkage of the core region of N-linked sugar chains.	Nitrogen	84-85	mannosidase beta	Homo sapiens	5-21
15858173-5	2005	Moreover, it was found that the glycosylation of SHPS-1 is N-linked in a muscle-specific manner, and that this is altered upon innervation or denervation.	Nitrogen	59-60	signal-regulatory protein alpha	Rattus norvegicus	49-55
15771433-3	2005	Attempts to optimize a cyclin-dependent kinase-1 (CDK1) inhibitor by using palladium-catalyzed C-C bond, C-N bond formation reactions to assemble diverse biheteroaryl molecules led to the unexpected discovery of a pyrazine-pyridine biheteroaryl as a novel series of potent VEGFR-2 inhibitors.	Nitrogen	107-108	cyclin dependent kinase 1	Homo sapiens	23-48
15771433-3	2005	Attempts to optimize a cyclin-dependent kinase-1 (CDK1) inhibitor by using palladium-catalyzed C-C bond, C-N bond formation reactions to assemble diverse biheteroaryl molecules led to the unexpected discovery of a pyrazine-pyridine biheteroaryl as a novel series of potent VEGFR-2 inhibitors.	Nitrogen	107-108	cyclin dependent kinase 1	Homo sapiens	50-54
15781627-8	2005	Cultured medium from these cells revealed a secreted form of HE4 that is N-glycosylated.	Nitrogen	73-74	WAP four-disulfide core domain 2	Homo sapiens	61-64
15732965-9	2005	The mechanism involves initial breaking of a metal-nitrogen bond, fast interconversion between two 14-electron three-coordinate T-shaped intermediates containing eta1-coordinated Me2-phen, and final ring closure.	Nitrogen	51-59	secreted phosphoprotein 1	Homo sapiens	162-166
15761611-4	2005	One protein, Pso2p, was shown to participate in the repair of DSBs induced by DNA inter-strand cross-linking (ICL) agents such as cisplatin, nitrogen mustard or photo-activated bi-functional psoralens.	Nitrogen	141-149	DNA cross-link repair 1A	Homo sapiens	13-18
16851119-3	2005	Over Na-Y, the reaction between HCN and NO(2) is slow at 473 K. On Ba-Y, HCN reacts readily with NO(2) at 473K, forming N(2), CO, CO(2), HNCO, NO, N(2)O, and C(2)N(2).	Nitrogen	120-124	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	73-76
15585365-6	2005	The results show that CYP3A4 contributes to the oxidation of KR-60436 to pyrrole-KR-60436, O-demethylpyrrole-KR-60436 and N-dehydroxyethyl-KR-60436, and CYP2C9 and CYP2D6 play roles in demethylation of KR-60436 to form the active metabolite, O-demethyl-KR-60436.	Nitrogen	122-123	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	153-159
16839104-1	2005	In this work, we present a topological study of the Laplacian of the electronic density using a 6-311++G basis set, at Hartree-Fock (HF) and second-order Moller-Plesset (MP2) (full-electron and frozen-core) levels of theory, for the carbocations 2-C-n-butonium generated upon the insertion of a proton into the secondary C-C bond during the protonation of n-butane.	Nitrogen	1-2	tryptase pseudogene 1	Homo sapiens	170-173
15470160-6	2005	These results suggest that trans-3"-hydroxycotinine N-glucuronidation in human liver microsomes would be mainly catalyzed by UGT1A4.	Nitrogen	52-53	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	125-131
16312994-0	2005	Applying real-time control to enhance the performance of nitrogen removal in CAST system.	Nitrogen	57-65	calpastatin	Homo sapiens	77-81
15589408-4	2005	The experiments are demonstrated on a uniformly (13)C,(15)N-labelled sample of Nac-Val-Leu-OH and applied to a uniformly (13)C,(15)N-enriched sample of a hexameric amyloidogenic peptide.	Nitrogen	58-59	synuclein alpha	Homo sapiens	79-82
15590139-10	2005	It was shown that the degree of oxidation was higher under high normal load and in a nitrogen environment, oxidation of the silicon tip was reduced.	Nitrogen	85-93	TOR signaling pathway regulator	Homo sapiens	132-135
15852983-5	2005	It was estimated that the amounts of N, P and COD entered into seawater through the marine culture in the Yellow Sea and Bohai Sea accounted for 2.8%, 5.3% and 1.8% of the amounts of corresponding land-based pollutants entered to the sea, respectively.	Nitrogen	37-38	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	113-116
15852983-5	2005	It was estimated that the amounts of N, P and COD entered into seawater through the marine culture in the Yellow Sea and Bohai Sea accounted for 2.8%, 5.3% and 1.8% of the amounts of corresponding land-based pollutants entered to the sea, respectively.	Nitrogen	37-38	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	63-66
15527836-2	2004	The CAT1 protein contains two conserved N-linked glycosylation sites in the third extracellular loops of the mouse, rat, and hamster receptors (mCAT1, rCAT1, and hCAT1, respectively).	Nitrogen	40-41	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	4-8
15578742-0	2004	Exact molecular mass determination of various forms of native and de-N-glycosylated human plasma-derived antithrombin by means of electrospray ionization ion trap mass spectrometry.	Nitrogen	69-70	serpin family C member 1	Homo sapiens	105-117
15645351-1	2004	Cyclophosphamide (CTX) is an alkylating agent related to nitrogen mustards whose anti-inflammatory and immunosuppressive effects have been utilised to treat selected cases of multiple sclerosis with a progressive and worsening course.	Nitrogen	57-65	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	18-21
15555920-0	2004	Inhibition of N-linked glycosylation prevents inclusion formation by the dystonia-related mutant form of torsinA.	Nitrogen	14-15	torsin family 1 member A	Homo sapiens	105-112
15328353-5	2004	The mouse DESC1 mRNA was present in epidermal, oral, and male reproductive tissues and directed the translation of a membrane-associated 60-kDa N-glycosylated protein with type II topology.	Nitrogen	18-19	transmembrane protease, serine 11e	Mus musculus	10-15
15465011-3	2004	In addition, we found that N-formylated HN (fHN) performed more potently as a ligand for FPRL1 than HN: in CHO-hFPRL1 cells, the effective concentration for the half-maximal response (EC(50)) value of HN was 3.5nM, while that of fHN was 0.012nM.	Nitrogen	27-28	formyl peptide receptor 2	Homo sapiens	89-94
15465011-3	2004	In addition, we found that N-formylated HN (fHN) performed more potently as a ligand for FPRL1 than HN: in CHO-hFPRL1 cells, the effective concentration for the half-maximal response (EC(50)) value of HN was 3.5nM, while that of fHN was 0.012nM.	Nitrogen	27-28	formyl peptide receptor 2	Homo sapiens	111-117
15470255-10	2004	Thus, PP2A and the Tor kinase pathway transduce stress and nitrogen starvation signals to Msn2p.	Nitrogen	59-67	stress-responsive transcriptional activator MSN2	Saccharomyces cerevisiae S288C	90-95
15381120-3	2004	UAS(NTR) is the binding site for the transcriptional activator, Gln3 whose intracellular localization responds to the nitrogen supply, accumulating in the nuclei of cells provided with poor nitrogen sources and in the cytoplasm when excess nitrogen is available.	Nitrogen	118-126	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	64-68
15381120-3	2004	UAS(NTR) is the binding site for the transcriptional activator, Gln3 whose intracellular localization responds to the nitrogen supply, accumulating in the nuclei of cells provided with poor nitrogen sources and in the cytoplasm when excess nitrogen is available.	Nitrogen	190-198	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	64-68
15381120-3	2004	UAS(NTR) is the binding site for the transcriptional activator, Gln3 whose intracellular localization responds to the nitrogen supply, accumulating in the nuclei of cells provided with poor nitrogen sources and in the cytoplasm when excess nitrogen is available.	Nitrogen	190-198	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	64-68
15383588-3	2004	The open reading frames for Gici-CD83 (194 aa) and Onmy-CD83 (218 aa) display approximately 28-32% identity to mammalian CD83 with the presence of two conserved N-linked glycosylation sites.	Nitrogen	161-162	CD83 molecule	Homo sapiens	33-37
15383588-3	2004	The open reading frames for Gici-CD83 (194 aa) and Onmy-CD83 (218 aa) display approximately 28-32% identity to mammalian CD83 with the presence of two conserved N-linked glycosylation sites.	Nitrogen	161-162	CD83 molecule	Homo sapiens	56-60
15383588-3	2004	The open reading frames for Gici-CD83 (194 aa) and Onmy-CD83 (218 aa) display approximately 28-32% identity to mammalian CD83 with the presence of two conserved N-linked glycosylation sites.	Nitrogen	161-162	CD83 molecule	Homo sapiens	56-60
15691018-4	2004	In addition, there is an accumulation of 18:1 n-9 and 18:2n-6 and a decrease in the end products of the n-3 metabolic pathway in PC, suggesting a dysfunctional delta-6-desaturase enzyme.	Nitrogen	1-2	fatty acid desaturase 2	Rattus norvegicus	160-178
15252044-5	2004	The oligosaccharide on a kAE1 S773P N-glycosylation mutant (N555) was not processed to the complex form indicating impaired exit from the endoplasmic reticulum.	Nitrogen	36-37	O-sialoglycoprotein endopeptidase	Homo sapiens	25-29
15366872-1	2004	Site-specific nitrogen-15 longitudinal relaxation rates are measured for the microcrystalline dimeric form of the protein Crh using multidimensional high-resolution solid-state NMR methods.	Nitrogen	14-22	corticotropin releasing hormone	Homo sapiens	122-125
15289885-5	2004	The Cox-2 protein was strongly induced 2 h after exposure to n-LDL or Ox-LDL, the induction was maximal after 4 h and sustained for at least 8 h. The effect was specific for Cox-2, as Cox-1 expression was not modulated either by n-LDL or by Ox-LDL.	Nitrogen	16-17	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	184-189
15197348-5	2004	The reduction in cell growth and enhancement in cell killing by the combination of GST-MDA-7 and radiation were blocked by an ROS scavenger, N-acetyl cysteine (NAC), a JNK1/2/3 inhibitor SP600125, a pan-caspase inhibitor (zVAD) and by an inhibitor of caspase 9 (LEHD), but not by an inhibitor of caspase 8 (IETD).	Nitrogen	141-142	interleukin 24	Homo sapiens	87-92
15117878-3	2004	We have previously reported that N-linked glycosylation of the extracellular domain of MCH1R is necessary for cell surface expression and signal transduction.	Nitrogen	33-34	melanin-concentrating hormone receptor 1	Rattus norvegicus	87-92
15253935-5	2004	In addition, we showed that N and eyg could induce expression of upd, which encodes the ligand for the Jak/STAT pathway and acts over long distance to promote cell proliferation.	Nitrogen	28-29	hopscotch	Drosophila melanogaster	103-106
15226418-6	2004	We found that large N-terminal tags also stabilize the expression of the cell cycle inhibitor p21 but not that of substrates ubiquitinated on internal lysine residues.	Nitrogen	20-21	H3 histone pseudogene 16	Homo sapiens	94-97
17134389-9	2004	Furthermore, fusion of KDEL to the diabody derivative of PIPP, which contains an N-glycosylation site within the heavy chain variable domain, also resulted in a molecule lacking complex glycans.	Nitrogen	81-82	inositol polyphosphate-5-phosphatase J	Homo sapiens	57-61
15163206-0	2004	Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.	Nitrogen	118-126	histamine receptor H3	Rattus norvegicus	86-107
15104463-3	2004	N-Deprotection by photoactivated bromination and acidic treatment leads to compounds 10 with various CO-R substituents at C-4.	Nitrogen	0-1	complement C4A (Rodgers blood group)	Homo sapiens	122-125
14757761-1	2004	Glutamine synthetase (GS; EC 6.3.1.2) is a key enzyme of nitrogen assimilation, catalyzing the synthesis of glutamine from ammonium and glutamate.	Nitrogen	57-65	hypothetical protein	Arabidopsis thaliana	0-20
14757761-7	2004	By contrast, the high affinity isoenzyme, GLN1;1 (Km for ammonium &lt; 10 microm; Km for glutamate = 1.1 +/- 0.4 mm) was abundantly accumulated in the surface layers of roots during nitrogen limitation and was down-regulated by ammonium excess.	Nitrogen	182-190	hypothetical protein	Arabidopsis thaliana	42-48
15039314-0	2004	N-linked glycosylation is required for c1 inhibitor-mediated protection from endotoxin shock in mice.	Nitrogen	0-1	serine (or cysteine) peptidase inhibitor, clade G, member 1	Mus musculus	39-51
15003263-8	2004	Only suPAR completely deprived of N-linked glycosylation exhibits an impaired level of secretion.	Nitrogen	34-35	Su(par)	Drosophila melanogaster	5-10
14699159-2	2004	ATF6, a 90-kDa ER transmembrane protein, contains three evolutionarily conserved N-linked glycosylation sites within its carboxyl luminal domain.	Nitrogen	81-82	activating transcription factor 6	Homo sapiens	0-4
14699159-5	2004	By mutating a single amino acid within the N-linked glycosylation site closest to the carboxyl terminus of p90ATF6, we recreated ATF6(f).	Nitrogen	43-44	activating transcription factor 6	Homo sapiens	110-114
14699159-8	2004	Additional analysis of p90ATF6 mutants targeting single or multiple N-glycosylation sites also showed higher constitutive transactivating activity than wild type ATF6.	Nitrogen	68-69	activating transcription factor 6	Homo sapiens	26-30
14672957-4	2004	Given that the activity of NAT1 depends on a reactive cysteine that can be a target for oxidants, we studied whether peroxynitrite, a highly reactive nitrogen species involved in human carcinogenesis, could inhibit the activity of endogenous NAT1 in MCF7 breast cancer cells.	Nitrogen	150-158	N-acetyltransferase 1	Homo sapiens	27-31
14729370-7	2004	With regard to the proposal that BaP may be activated by human CYP1A1, our results suggest that the nitrogen-substitution at position-10 of BaP may cause the CYP enzyme-specificity in metabolic activation to change from CYP1A1 to CYP1A2.	Nitrogen	100-108	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	63-69
14729370-7	2004	With regard to the proposal that BaP may be activated by human CYP1A1, our results suggest that the nitrogen-substitution at position-10 of BaP may cause the CYP enzyme-specificity in metabolic activation to change from CYP1A1 to CYP1A2.	Nitrogen	100-108	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	220-226
14729370-7	2004	With regard to the proposal that BaP may be activated by human CYP1A1, our results suggest that the nitrogen-substitution at position-10 of BaP may cause the CYP enzyme-specificity in metabolic activation to change from CYP1A1 to CYP1A2.	Nitrogen	100-108	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	230-236
14664838-1	2004	Colored N-containing MOx-ZnO (M = W, V) composite powders with high surface area were synthesized by spray pyrolysis.	Nitrogen	8-9	monooxygenase DBH like 1	Homo sapiens	21-24
14664838-3	2004	Ultraviolet-visible spectra indicated that the N-containing MOx-ZnO powders absorbed not only ultraviolet light like pure ZnO powder, but also some visible-light.	Nitrogen	47-48	monooxygenase DBH like 1	Homo sapiens	60-63
14664838-6	2004	This enhancement was ascribed to the MOx acting as a sink for photogenerated electrons in the UV case, and to a synergistic effect of N-doping and MOx-ZnO coupling in the case of visible-light.	Nitrogen	134-135	monooxygenase DBH like 1	Homo sapiens	37-40
14764083-0	2004	The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis.	Nitrogen	12-13	lactotransferrin	Bos taurus	73-84
14764083-5	2004	Apparently, the previously reported protection by N-linked glycosylation of hLF [van Berkel, P.H.C., Geerts, M.E.J., van Veen, H.A., Kooiman, P.M., Pieper, F., de Boer, H.A.	Nitrogen	50-51	HLF transcription factor, PAR bZIP family member	Homo sapiens	76-79
15282944-8	2004	Information on the relationship between nitrogen fixation and carbon metabolism through PEPC in leguminous plants is scanty and incoherent.	Nitrogen	40-48	phosphoenolpyruvate carboxykinase 1	Homo sapiens	88-92
14648201-3	2004	We found that loss of G1 cyclins, or inactivation of the cyclin-dependent kinase Cdc28p, reduced the activity of glutamate synthase (Glt1p), a key enzyme in nitrogen assimilation.	Nitrogen	157-165	cyclin-dependent serine/threonine-protein kinase CDC28	Saccharomyces cerevisiae S288C	81-87
14731272-1	2004	SIT4 encodes the multifunctional catalytic subunit of a type 2A-related protein phosphatase of Saccharomyces cerevisiae and has been implicated in cell cycle regulation and nitrogen sensing.	Nitrogen	173-181	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	0-4
14989432-6	2004	CONCLUSION: The molecular mass difference in the BSSL molecular forms cannot be attributed to the type of carbohydrate moiety in the sugar chains of the N- and O-linked sites suggesting that the differences arise from the extent or quantity of glycosylation.	Nitrogen	2-3	carboxyl ester lipase	Homo sapiens	49-53
14709623-8	2004	Overexpressed UDP-glucuronosyltransferase (UGT) 1A4 exhibited significant levels of N-glucuronidating activity (V(max)/K(m) = 3.11 microl.	Nitrogen	84-85	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	14-51
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	interleukin 23 subunit alpha	Homo sapiens	124-129
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	interleukin 23 subunit alpha	Homo sapiens	124-129
14872536-1	2004	Saturation transfer experiments were performed for the (2)H- and (15)N-labeled mouse CAD domain of the caspase-activated deoxyribonuclease and the CAD domain of its inhibitor to reveal the protein-protein complexed conformation.	Nitrogen	69-70	DNA fragmentation factor, beta subunit	Mus musculus	103-138
14658918-6	2003	The second cadmium ion (Cd2) in this compound lies below the plane of three nitrogen atoms, N(6), N(8), and N(9).	Nitrogen	76-84	CD2 molecule	Homo sapiens	24-27
14603468-3	2003	Since the main site of PLA2 action in inflammatory processes is the cell membrane, we synthesized extracellular PLA2 inhibitors (ExPLIs) composed of N-derivatized phosphatidyl-ethanolamine linked to polymeric carriers.	Nitrogen	149-150	phospholipase A2 group IB	Rattus norvegicus	112-116
14559239-1	2003	It has been considered that three key elements participate in nitrogen catabolite repression (NCR) of Saccharomyces cerevisiae: the GLN3 and GAT1/NIL1-encoded transcriptional activators and their negative regulator Ure2.	Nitrogen	62-70	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	132-136
12851403-7	2003	We show that (i) retrograde gene expression correlates with intracellular ammonia and alpha-ketoglutarate generated by a nitrogen source rather than the severity of NCR it elicits, and (ii) in addition to its known regulation by NCR, NAD-glutamate dehydrogenase (GDH2) gene expression is down-regulated by ammonia under conditions where NCR is minimal.	Nitrogen	121-129	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	263-267
12954207-6	2003	In this study, guided by the X-ray crystal structure of gp120, we deleted four N-linked glycosylation sites that flank the receptor-binding regions.	Nitrogen	79-80	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	56-61
12954207-8	2003	Surprisingly, removal of a single N-linked glycosylation site at the base of the gp120 third variable region (V3 loop) increased the sensitivity of the primary viruses to neutralization by CD4BS antibodies.	Nitrogen	34-35	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	81-86
12895109-0	2003	Theoretical characterization of stable eta1-N2O-, eta2-N2O-, eta1-N2-, and eta2-N2-bound species: intermediates in the addition reactions of nitrogen hydrides with the pentacyanonitrosylferrate(II) ion.	Nitrogen	141-149	secreted phosphoprotein 1	Homo sapiens	39-43
12895109-0	2003	Theoretical characterization of stable eta1-N2O-, eta2-N2O-, eta1-N2-, and eta2-N2-bound species: intermediates in the addition reactions of nitrogen hydrides with the pentacyanonitrosylferrate(II) ion.	Nitrogen	141-149	secreted phosphoprotein 1	Homo sapiens	61-65
12904166-4	2003	IGFBP-4, the smallest IGFBP, exists in both non-glycosylated and N-glycosylated forms in all biological fluids.	Nitrogen	65-66	insulin like growth factor binding protein 1	Homo sapiens	0-5
12623776-9	2003	Pretreatment of rabbits with 5 or 50 microg of NS-398 blocked the TNF-alpha-induced increases in non-rapid eye movement sleep, electroencephalographic slow-wave activity, and brain temperature.	Nitrogen	47-49	tumor necrosis factor	Oryctolagus cuniculus	66-75
19882697-0	2009	The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists.	Nitrogen	19-27	adrenoceptor beta 3	Homo sapiens	107-125
19882697-4	2009	Some piperazine sulfonamides were found to be potent and selective beta(3)-AR agonists, even if the amine nitrogen atom is tertiary and not secondary, as is the case for all beta(3)-AR agonists reported so far.	Nitrogen	106-114	adrenoceptor beta 3	Homo sapiens	67-77
19940927-3	2009	Here we show that the FEN1 gene of a model legume, Lotus japonicus, overcomes the lack of NifV in rhizobia for symbiotic nitrogen fixation.	Nitrogen	121-129	multifunctional nuclease RAD27	Saccharomyces cerevisiae S288C	22-26
19940927-7	2009	Inoculation with Mesorhizobium loti carrying FEN1 or Azotobacter vinelandii NifV rescued the defect in nitrogen-fixing activity of the fen1 nodules.	Nitrogen	103-111	multifunctional nuclease RAD27	Saccharomyces cerevisiae S288C	45-49
19940927-7	2009	Inoculation with Mesorhizobium loti carrying FEN1 or Azotobacter vinelandii NifV rescued the defect in nitrogen-fixing activity of the fen1 nodules.	Nitrogen	103-111	multifunctional nuclease RAD27	Saccharomyces cerevisiae S288C	135-139
19940927-8	2009	Exogenous supply of homocitrate also recovered the nitrogen-fixing activity of the fen1 nodules through de novo nitrogenase synthesis in the rhizobial bacteroids.	Nitrogen	51-59	multifunctional nuclease RAD27	Saccharomyces cerevisiae S288C	83-87
19901341-5	2009	Moreover, Dot6 and Tod6 mediate different nutrient signals, with Tod6 responsible for efficient repression of Ribi genes after inhibition of the nitrogen-sensitive TORC1 pathway and Dot6 responsible for repression after inhibition of the carbon-sensitive protein kinase A signaling pathway.	Nitrogen	145-153	Tod6p	Saccharomyces cerevisiae S288C	19-23
19901341-5	2009	Moreover, Dot6 and Tod6 mediate different nutrient signals, with Tod6 responsible for efficient repression of Ribi genes after inhibition of the nitrogen-sensitive TORC1 pathway and Dot6 responsible for repression after inhibition of the carbon-sensitive protein kinase A signaling pathway.	Nitrogen	145-153	Tod6p	Saccharomyces cerevisiae S288C	65-69
19912645-2	2009	The hypothesis for this study was that disregulated production of reactive oxygen species (ROS) and nitrogen species (RNS) mediates matrix protein and DNA modifications, which result in excessive fibroblastic proliferation.	Nitrogen	100-108	FAM20C golgi associated secretory pathway kinase	Homo sapiens	118-121
19821588-4	2009	Our in situ SAXS/SANS experiments took advantage of contrast matching of nitrogen (SANS, T = 77 K) and dibromomethane (SAXS, T = 290 K).	Nitrogen	73-81	USH1 protein network component sans	Homo sapiens	17-21
19693772-0	2009	N-glycosylation of ATF6beta is essential for its proteolytic cleavage and transcriptional repressor function to ATF6alpha.	Nitrogen	0-1	activating transcription factor 6	Homo sapiens	112-121
19693772-2	2009	ATF6beta contains five evolutionarily conserved N-linked glycosylation sites and is a key transcriptional repressor of ATF6alpha, which contribute to regulating the strength and duration of ATF6-dependent ER stress response (ERSR) gene induction.	Nitrogen	48-49	activating transcription factor 6	Homo sapiens	0-4
19693772-3	2009	Although it is well established that p110ATF6beta can be cleaved and generate a nuclear form of 60-kDa (p60ATF6beta) that inhibits ATF6alpha-mediated ERSR genes activation, the functional significance of p110 ATF6beta N-linked glycosylation is unknown.	Nitrogen	218-219	activating transcription factor 6	Homo sapiens	131-140
19693772-3	2009	Although it is well established that p110ATF6beta can be cleaved and generate a nuclear form of 60-kDa (p60ATF6beta) that inhibits ATF6alpha-mediated ERSR genes activation, the functional significance of p110 ATF6beta N-linked glycosylation is unknown.	Nitrogen	218-219	spliceosome associated factor 3, U4/U6 recycling protein	Homo sapiens	37-41
19849830-0	2009	Reduction of nitrogen compounds in oceanic basement and its implications for HCN formation and abiotic organic synthesis.	Nitrogen	13-21	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	77-80
19849830-2	2009	Reduced carbon and nitrogen precursor compounds for the synthesis of HCN may be formed under off-axis hydrothermal conditions in oceanic lithosphere in the presence of native Fe and Ni and are adsorbed on authigenic layer silicates and zeolites.	Nitrogen	19-27	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	69-72
19654028-7	2009	In contrast, we show that N-glycosylation of the extracellular part might participate in directing DR6 into these membrane microdomains.	Nitrogen	26-27	TNF receptor superfamily member 21	Homo sapiens	99-102
19754436-3	2009	Lipid droplets grow in size by fusion, which is dependent on dynein and the transfer on microtubules, and is catalysed by the SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) proteins SNAP-23 (23 kDa synaptosome-associated protein), syntaxin-5 and VAMP-4 (vesicle-associated protein 4).	Nitrogen	127-128	vesicle associated membrane protein 4	Homo sapiens	285-291
19574570-9	2009	We conclude that UT-B transporters play a significant role in the dietary regulation of bovine nitrogen balance.	Nitrogen	95-103	solute carrier family 14 member 1	Bos taurus	17-21
19916043-5	2009	Similar to other human group C rotaviruses, one N-glycosylation site was predicted at amino acid residue 67 on the VP7 of strain GUP188.	Nitrogen	48-49	outer capsid protein	Rotavirus C	115-118
19736979-2	2009	This model favors the reduction of the outermost iron with His87 and Cys83 ligands, which is supported by orientation-selected hyperfine sublevel correlation (HYSCORE) characterization of the uniformly (15)N-labeled mitoNEET showing one strongly coupled nitrogen from the His87 N(delta) ligand with hyperfine coupling (15)a = 8 MHz.	Nitrogen	254-262	CDGSH iron sulfur domain 1	Homo sapiens	216-224
19171192-3	2009	Based on the iso-electric focusing patterns of plasma transferrin and apolipoprotein C-III a combined defect in N- and O-glycosylation was identified in patients with autosomal recessive cutis laxa type II (ARCL II).	Nitrogen	112-113	apolipoprotein C3	Homo sapiens	70-90
19941415-3	2009	Rhodopsin is N-glycosylated at Asn-2 and Asn-15 in its extracellular N-terminal domain.	Nitrogen	13-14	rhodopsin	Mus musculus	0-9
19904008-3	2009	The Dixon analysis showed that in both human liver microsomes and Supersomes CYP1A2 perazine potently and to a similar degree inhibited caffeine 3-N-demethylation (K(i) = 3.5 microM) and 1-N-demethylation (K(i) = 5 microM).	Nitrogen	147-148	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	77-83
19478090-1	2009	It is well established that proper N-glycosylation significantly influences the efficacy of monoclonal antibodies (mAbs).	Nitrogen	35-36	DEAD box helicase 41	Mus musculus	115-119
19478090-3	2009	Here we report on the generation of a plant-based expression platform allowing the efficient production of mAbs with a homogeneous beta1,4-galactosylated N-glycosylation structure, the major N-glycan species present on serum IgG.	Nitrogen	154-155	DEAD box helicase 41	Mus musculus	107-111
19371088-2	2009	These three relatives catalyze substrate acyl-adenylation and nucleophilic acyl substitution by either an external (AS-B) or internal (CPS, beta-LS) nitrogen source.	Nitrogen	149-157	arylsulfatase B	Homo sapiens	116-120
18848326-5	2009	It was observed that feeding of diets with n-6 PUFA or a combination of n-6 and n-3 PUFAs resulted in marked elevation of plasma levels of total as well as HDL cholesterol and triglycerides in obese rats (BII and BIII), as compared to the control group (BI).	Nitrogen	26-27	calcium voltage-gated channel subunit alpha1 B	Rattus norvegicus	213-217
19036570-8	2009	Gas6 median value in the N group (20.4ng/mL, interquartile range 17.6-21.6) matched that of healthy volunteers, 19.1 (17.2-21.4).	Nitrogen	25-26	growth arrest specific 6	Homo sapiens	0-4
19182781-7	2009	Examination of the planktonic membrane lipids at these two locations showed that classes of sulphur- and nitrogen-containing membrane lipids, which are devoid of phosphorus, were more abundant in the Sargasso Sea than in the South Pacific.	Nitrogen	105-113	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	209-212
19189049-1	2009	The PAS domain kinase PASKIN, also termed PAS kinase or PASK, is an evolutionarily conserved potential sensor kinase related to the heme-based oxygen sensors of nitrogen-fixing bacteria.	Nitrogen	161-169	PAS domain containing serine/threonine kinase	Mus musculus	22-28
19189049-1	2009	The PAS domain kinase PASKIN, also termed PAS kinase or PASK, is an evolutionarily conserved potential sensor kinase related to the heme-based oxygen sensors of nitrogen-fixing bacteria.	Nitrogen	161-169	PAS domain containing serine/threonine kinase	Mus musculus	42-52
19189049-1	2009	The PAS domain kinase PASKIN, also termed PAS kinase or PASK, is an evolutionarily conserved potential sensor kinase related to the heme-based oxygen sensors of nitrogen-fixing bacteria.	Nitrogen	161-169	PAS domain containing serine/threonine kinase	Mus musculus	22-26
19125635-2	2009	Experimental findings reveal the presence of a methyl group on C-2 of the pyrrolidine ring as an essential requirement for the cyclization process, whereas the existence of a H-bond between a second hydroxylic group and the nitrogen atom of the pyrrolidine ring seems to favor the approaching geometry without determining the reaction outcome.	Nitrogen	224-232	complement C2	Homo sapiens	63-66
19037902-6	2009	Detailed biochemical analyses on the purified protein revealed that it was N-glycosylated, predominantly with high-mannose-type glycans (more than 75%), as predicted from a consensus asparagine-X-serine/threonine (Asn-X-Ser/Thr) N-glycosylation sequon on the CTB domain and an endoplasmic reticulum retention signal attached at the C-terminus of the fusion protein.	Nitrogen	75-76	chitobiase	Homo sapiens	259-262
19015262-1	2009	Gln3, the major activator of nitrogen catabolite repression (NCR)-sensitive transcription, is often used as an assay of Tor pathway regulation in Saccharomyces cerevisiae.	Nitrogen	29-37	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
19015262-2	2009	Gln3 is cytoplasmic in cells cultured with repressive nitrogen sources (Gln) and nuclear with derepressive ones (Pro) or after treating Gln-grown cells with the Tor inhibitor, rapamycin (Rap).	Nitrogen	54-62	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
19015262-7	2009	However, because PP2A is not required for nuclear Gln3 localization in Pro, PP2A-dependent Gln3 dephosphorylation and nuclear localization are likely parallel responses to derepressive nitrogen sources.	Nitrogen	185-193	protein phosphatase 2 phosphatase activator	Homo sapiens	76-80
19118500-4	2009	We found that noise in the expression of a key enzyme in ammonia assimilation, Gdh1p, mediated a tradeoff between growth in low nitrogen environments and stress resistance in high ammonia environments.	Nitrogen	128-136	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	79-84
19113978-7	2009	Analysis of cysteine residues, lengths of variable regions, and potential N-linked glycosylation sites in gp120 and gp41 was performed.	Nitrogen	74-75	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	106-111
19113978-13	2009	The number of potential N-linked glycosylation sites in gp120 and gp41 ranged between 24-29 and 4-6, respectively.	Nitrogen	24-25	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	56-61
19113978-14	2009	Seven potential N-linked glycosylation sites in gp120 and three in gp41 were conserved.	Nitrogen	16-17	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	48-53
19007158-7	2008	Instead, under more drastic conditions, reactions of PSH with [M(N)Cl(2)(PPh(3))(2)] gave a mixture of monosubstituted [M(N)(PS)Cl(PPh(3))] and bis-substituted species [M(N)(PS)(2)] (Tc11-14) in the case of technetium, whereas only monosubstituted [M(N)(PS)Cl(PPh(3))] complexes were recovered for rhenium.	Nitrogen	64-67	protein phosphatase 4 catalytic subunit	Homo sapiens	73-79
19007158-7	2008	Instead, under more drastic conditions, reactions of PSH with [M(N)Cl(2)(PPh(3))(2)] gave a mixture of monosubstituted [M(N)(PS)Cl(PPh(3))] and bis-substituted species [M(N)(PS)(2)] (Tc11-14) in the case of technetium, whereas only monosubstituted [M(N)(PS)Cl(PPh(3))] complexes were recovered for rhenium.	Nitrogen	64-67	protein phosphatase 4 catalytic subunit	Homo sapiens	131-137
19007158-7	2008	Instead, under more drastic conditions, reactions of PSH with [M(N)Cl(2)(PPh(3))(2)] gave a mixture of monosubstituted [M(N)(PS)Cl(PPh(3))] and bis-substituted species [M(N)(PS)(2)] (Tc11-14) in the case of technetium, whereas only monosubstituted [M(N)(PS)Cl(PPh(3))] complexes were recovered for rhenium.	Nitrogen	64-67	protein phosphatase 4 catalytic subunit	Homo sapiens	131-137
19057078-3	2008	The N atom in the C-2 side chain is protonated in both structures and is involved in the hydrogen-bonding networks.	Nitrogen	4-5	complement C2	Homo sapiens	18-21
18930088-7	2008	The gastroprotective effect of N/OFQ (1 nmol), but not that of NST (1 nmol), was reduced by the selective nociceptin receptor antagonist J-113397 (69 nmol i.c.v.).	Nitrogen	31-32	prepronociceptin	Rattus norvegicus	106-116
18766373-9	2008	We have demonstrated that dark, nitrogen nutrients, and auxin apparently affect the anthocyanin profiles in PAP1 transgenic callus cultures; and suggest that these cell cultures are an appropriate system to study the regulatory function of PAP1 on the anthocyanin biosynthesis at post-transcriptional level in vivo.	Nitrogen	32-40	phosphatidic acid phosphatase 1	Arabidopsis thaliana	108-112
18766373-9	2008	We have demonstrated that dark, nitrogen nutrients, and auxin apparently affect the anthocyanin profiles in PAP1 transgenic callus cultures; and suggest that these cell cultures are an appropriate system to study the regulatory function of PAP1 on the anthocyanin biosynthesis at post-transcriptional level in vivo.	Nitrogen	32-40	phosphatidic acid phosphatase 1	Arabidopsis thaliana	240-244
18809682-1	2008	The second step of eukaryotic N-linked glycosylation in endoplasmic reticulum is catalyzed by an UDP-N-acetylglucosamine transferase that is comprised of two subunits, Alg13 and Alg14.	Nitrogen	30-31	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13	Saccharomyces cerevisiae S288C	168-173
18950143-4	2008	In addition to the deprotonation of the hydroxyl oxygen, ab initio calculations performed at the MP2/6-311++G(d,p) level of theory for these two compounds indicate a notable participation of the nitrogen deprotonation site in HU.	Nitrogen	195-203	tryptase pseudogene 1	Homo sapiens	97-100
19080126-15	2008	Finally the expression of CTGF after the irradiation of the kidney positively correlated with the levels of blood urea nitrogen and serum creatinine.	Nitrogen	119-127	cellular communication network factor 2	Rattus norvegicus	26-30
18782110-2	2008	We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensitizes human CCR3 resulting in the inactivation of eosinophils.	Nitrogen	23-24	C-C motif chemokine ligand 14	Homo sapiens	76-81
18782110-2	2008	We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensitizes human CCR3 resulting in the inactivation of eosinophils.	Nitrogen	23-24	C-C motif chemokine ligand 14	Homo sapiens	139-144
18647303-8	2008	Using recombinant CYP3A4, N-dealkylation was characterized by a K(m) of 13 microM and a V(max) of 3 pmol pmol(-1) CYP min(-1).	Nitrogen	26-27	peptidylprolyl isomerase G	Homo sapiens	18-21
18978034-8	2008	Broad-range metabolite profiling of the old5 mutant revealed that it contains higher levels of tricarboxylic acid cycle intermediates and nitrogen-containing amino acids.	Nitrogen	138-146	quinolinate synthase	Arabidopsis thaliana	40-44
18721313-0	2008	Supply of nitrogen can reverse senescence processes and affect expression of genes coding for plastidic glutamine synthetase and lysine-ketoglutarate reductase/saccharopine dehydrogenase.	Nitrogen	10-18	hypothetical protein	Arabidopsis thaliana	104-124
18571851-3	2008	In this study we explored the gene transcription of activity-dependent neuroprotective protein (ADNP) in neonatal rat brain as consequence to xenon exposure, comparing the noble gas to nitrogen.	Nitrogen	185-193	activity-dependent neuroprotector homeobox	Rattus norvegicus	52-94
18571851-3	2008	In this study we explored the gene transcription of activity-dependent neuroprotective protein (ADNP) in neonatal rat brain as consequence to xenon exposure, comparing the noble gas to nitrogen.	Nitrogen	185-193	activity-dependent neuroprotector homeobox	Rattus norvegicus	96-100
18639462-0	2008	Nitrogen-containing flavonoid analogues as CDK1/cyclin B inhibitors: synthesis, SAR analysis, and biological activity.	Nitrogen	0-8	cyclin dependent kinase 1	Homo sapiens	43-47
18639462-2	2008	The results showed that C-8 nitrogen-containing baicalein analogues 3a-3f exhibited potent CDK1/Cyclin B inhibitory activities.	Nitrogen	28-36	cyclin dependent kinase 1	Homo sapiens	91-95
18474681-0	2008	Regio- and stereospecific N-glucuronidation of medetomidine: the differences between UDP glucuronosyltransferase (UGT) 1A4 and UGT2B10 account for the complex kinetics of human liver microsomes.	Nitrogen	26-27	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	127-134
18501631-0	2008	Improved secretion of human Fas ligand extracellular domain by N-terminal part truncation in Pichia pastoris and preparation of the N-linked carbohydrate chain trimmed derivative.	Nitrogen	63-64	Fas ligand	Homo sapiens	28-38
18501631-2	2008	The influence of N-terminal part (Q103-P138) truncation of human Fas ligand extracellular domain (hFasLECD) on the expression of N-terminal FLAG-(Gly)(5)-tagged hFasLECD (NFG5-hFasLECD) with partial N-glycosylation-sites deletion in Pichia pastoris was investigated.	Nitrogen	17-18	Fas ligand	Homo sapiens	65-75
18671849-11	2008	VEGF was significantly reduced following the treatment of NS-398 in A549 (by 31%) and MOR/P (by 47%) cells lines which expressing strong COX-2, but not in H460 cell line which expressing very low COX-2.	Nitrogen	58-60	opioid receptor mu 1	Homo sapiens	86-89
19469122-2	2008	It has been proven that calm breathing of 100% oxygen allows for removal of 95% of the nitrogen from the body, replacing it with oxygen.	Nitrogen	87-95	synaptosome associated protein 91	Homo sapiens	24-28
18533687-5	2008	We herein investigate the actual N-linked glycosylation status of RXFP1 and the functional ramifications of these post-translational modifications.	Nitrogen	33-34	relaxin family peptide receptor 1	Homo sapiens	66-71
18533687-8	2008	All of the potential N-glycosylation sites of RXFP1 were utilized in HEK-293T cells, and importantly, disruption of glycosylation at individual or combinations of double and triple sites had little effect on relaxin binding.	Nitrogen	21-22	relaxin family peptide receptor 1	Homo sapiens	46-51
18533687-10	2008	In particular, N-glycosylation at Asn-303 of RXFP1 was required for optimal intracellular cAMP signaling.	Nitrogen	15-16	relaxin family peptide receptor 1	Homo sapiens	45-50
18612543-5	2008	After six weeks of treatment with horse spleen apoferritin and lipoplysaccharide to induce glomerulonephritis, mice deficient in TAFI had significantly better renal function as shown by lower concentrations of albumin in urine and blood urea nitrogen compared to wild-type mice.	Nitrogen	242-250	carboxypeptidase B2 (plasma)	Mus musculus	129-133
18425424-6	2008	Inhibition of N-glycosylation by tunicamycin reduced both the enzymatic activity of extracellular NEP2 and the molecular size of intracellular NEP2.	Nitrogen	14-15	membrane metallo-endopeptidase-like 1	Mus musculus	98-102
18425424-6	2008	Inhibition of N-glycosylation by tunicamycin reduced both the enzymatic activity of extracellular NEP2 and the molecular size of intracellular NEP2.	Nitrogen	14-15	membrane metallo-endopeptidase-like 1	Mus musculus	143-147
18430363-10	2008	Lipid-loaded VSMC exposed to N-acetyl- Leu-Leu-norleucinal, a SREBP-1 protease inhibitor, showed increased nuclear translocation of SREBP-1, reduced caveolin-1 expression level, and upregulated cellular lipid levels.	Nitrogen	29-30	sterol regulatory element binding transcription factor 1	Mus musculus	62-69
18430363-10	2008	Lipid-loaded VSMC exposed to N-acetyl- Leu-Leu-norleucinal, a SREBP-1 protease inhibitor, showed increased nuclear translocation of SREBP-1, reduced caveolin-1 expression level, and upregulated cellular lipid levels.	Nitrogen	29-30	sterol regulatory element binding transcription factor 1	Mus musculus	132-139
18430363-10	2008	Lipid-loaded VSMC exposed to N-acetyl- Leu-Leu-norleucinal, a SREBP-1 protease inhibitor, showed increased nuclear translocation of SREBP-1, reduced caveolin-1 expression level, and upregulated cellular lipid levels.	Nitrogen	29-30	caveolin 1, caveolae protein	Mus musculus	149-159
18281025-1	2008	1",2,3,3",4,4"-Hexa-O-benzyl-sucrose was converted in good yields into the macrocyclic receptors containing two and three nitrogen atoms in the ring.	Nitrogen	122-130	hexosaminidase subunit alpha	Homo sapiens	15-19
17624598-3	2008	The nitrogen content was increased by 4.5 times due to addition of nitrogen fixing strains of Bradyrhizobium and Azotobacter species, while phosphate content was increased by 10.0 times due to addition of VAM, which helps in phosphate immobilization.	Nitrogen	4-12	vam	Drosophila melanogaster	205-208
18288776-4	2008	Results showed that the N-desulfated heparin had a similar affinity for G-CSF ((5.4 +/- 0.9) x 10(5) M(-1)), but the 2,3-O-desulfated heparin had a 1000-fold lower affinity ((3.4 +/- 1.2) x 10(2) M(-1)) in comparison to standard heparin.	Nitrogen	24-25	colony stimulating factor 3	Homo sapiens	72-77
18245858-5	2008	atg10-1 plants are hypersensitive to nitrogen and carbon starvation and initiate senescence and programmed cell death (PCD) more quickly than wild type, as indicated by elevated levels of senescence- and PCD-related mRNAs and proteins during carbon starvation.	Nitrogen	37-45	meiotically up-regulated protein	Arabidopsis thaliana	0-7
18237164-9	2008	Finally, molecular dynamics (MD) simulations, in the gas phase and in water, of CGPC, CGGC, and the corresponding wild-type Trx and P34G Trx show that the activity of the thioredoxin active-site motif (CXYC) is determined not only by the structural rigidity associated with the particular variable residues (XY) but also by the number of amide N-H groups.	Nitrogen	344-345	thioredoxin	Homo sapiens	171-182
17980859-6	2008	Kinetic and inhibition studies indicated that the side-chain N-dealkylation is mediated by CYP2C11 and CYP3A2, whereas the aromatic ring O-demethylation is mediated by CYP2D2 and CYP2C6 in untreated male rats.	Nitrogen	61-62	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	91-98
18337696-3	2008	When the Pap1-positive KP1 cells were transferred to the nitrogen-depleted medium, total GSH level significantly increased up to 6 h and then slightly declined after 9 h. Elevation of the total GSH level was observed to be much less with the Pap1-negative cells.	Nitrogen	57-65	lipin 1	Homo sapiens	9-13
18337696-3	2008	When the Pap1-positive KP1 cells were transferred to the nitrogen-depleted medium, total GSH level significantly increased up to 6 h and then slightly declined after 9 h. Elevation of the total GSH level was observed to be much less with the Pap1-negative cells.	Nitrogen	57-65	lipin 1	Homo sapiens	242-246
18337696-8	2008	Collectively, nitrogen depletion causes up-regulation of GSH synthesis and gamma-GT in a Pap1-dependent manner.	Nitrogen	14-22	lipin 1	Homo sapiens	89-93
19137904-2	2008	Six new tri- and tetracyclic nitrogen bridgehead compounds known to be moderate to potent inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in vitro were tested in vivo as experimental therapeutics for treatment of Alzheimer"s disease.	Nitrogen	29-37	acetylcholinesterase	Rattus norvegicus	104-124
19137904-2	2008	Six new tri- and tetracyclic nitrogen bridgehead compounds known to be moderate to potent inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in vitro were tested in vivo as experimental therapeutics for treatment of Alzheimer"s disease.	Nitrogen	29-37	acetylcholinesterase	Rattus norvegicus	126-130
17979996-0	2008	Nitrogen-containing bisphosphonate, YM529/ONO-5920, inhibits macrophage inflammatory protein 1 alpha expression and secretion in mouse myeloma cells.	Nitrogen	0-8	chemokine (C-C motif) ligand 3	Mus musculus	61-100
18449873-9	2008	It showed a terminal bidentate chloranilato ligand and N,N-bidentate coordination of ligand HL1, which illustrates the flexible coordination chemistry of ligand L1.	Nitrogen	55-56	intelectin 1	Homo sapiens	92-95
18449873-9	2008	It showed a terminal bidentate chloranilato ligand and N,N-bidentate coordination of ligand HL1, which illustrates the flexible coordination chemistry of ligand L1.	Nitrogen	57-58	intelectin 1	Homo sapiens	92-95
18552353-0	2008	Adaptation of Arabidopsis to nitrogen limitation involves induction of anthocyanin synthesis which is controlled by the NLA gene.	Nitrogen	29-37	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	120-123
18552353-2	2008	However, the Arabidopsis nla (nitrogen limitation adaptation) mutant fails to produce such responses, and cannot adapt to N limitation.	Nitrogen	30-38	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	25-28
18552353-5	2008	In contrast, when supplied with limiting N and limiting phosphorus (Pi), the nla mutants accumulated abundant anthocyanins and did not show the N limitation-induced early senescence phenotype.	Nitrogen	41-42	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	77-80
17804460-9	2008	RHS-TM significantly decreased blood urea nitrogen and serum creatinine levels.	Nitrogen	42-50	thrombomodulin	Homo sapiens	4-6
17971303-2	2007	Blood urea nitrogen (BUN) and serum creatinine were significantly higher in ASK1+/+ mice than in ASK1-/- mice after I/R injury.	Nitrogen	11-19	mitogen-activated protein kinase kinase kinase 5	Mus musculus	76-80
18044837-2	2007	"Cortina") lines expressing the asparagine synthetase A gene from Escherichia coli were produced to alter the plant nitrogen status and eventually enhance growth.	Nitrogen	116-124	asparagine synthetase A	Escherichia coli	32-55
18052314-2	2007	MT1 and MT2 receptor binding affinity and intrinsic activity have been modulated by the introduction of different substituents on the aniline nitrogen, on the benzene ring, and on the amide side chain.	Nitrogen	142-150	metallothionein 1I, pseudogene	Homo sapiens	0-3
18052314-2	2007	MT1 and MT2 receptor binding affinity and intrinsic activity have been modulated by the introduction of different substituents on the aniline nitrogen, on the benzene ring, and on the amide side chain.	Nitrogen	142-150	metallothionein 2A	Homo sapiens	8-11
18240680-0	2007	Tradeoffs between environmental goals and urban development: the case of nitrogen load from the Stockholm County to the Baltic Sea.	Nitrogen	73-81	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	127-130
18240680-3	2007	The effects of urban development were estimated through the quantification of nitrogen (N) leakage to the Baltic Sea under two urban development scenarios.	Nitrogen	78-86	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	113-116
18240680-5	2007	Technical improvements in sewage treatment could, according to our results, decrease total N load to the Baltic Sea by 4%.	Nitrogen	91-92	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	112-115
17885809-12	2007	This study presents a genome-wide view of Arabidopsis transcriptome response to nitrogen limitation and its regulation by NLA, and provides information to probe the molecular mechanism controlling plant adaptability to nitrogen limitation.	Nitrogen	219-227	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	122-125
17967019-7	2007	A key step is the oxygen insertion into a Ta-N bond in 1 through an intersystem conversion from triplet to singlet energy surface to give an active peroxide complex (Me2N)4Ta(eta2-O-O-NMe2) (A4).	Nitrogen	45-46	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	184-188
17980170-11	2007	We next determined N-glycosylation sites of human NAAA by site-directed mutagenesis addressed to asparagine residues in six potential N-glycosylation sites.	Nitrogen	19-20	N-acylethanolamine acid amidase	Homo sapiens	50-54
17950489-5	2007	We also suggest that N/OFQ may promote anti-inflammatory actions via suppression of IL-2 in vivo.	Nitrogen	21-22	interleukin 2	Rattus norvegicus	84-88
17726031-5	2007	P4H-TM levels in cultured cells are increased by hypoxia, and P4H-TM is N-glycosylated and is located in endoplasmic reticulum membranes with its catalytic site inside the lumen, a location differing from those of the HIF-P4Hs.	Nitrogen	72-73	prolyl 4-hydroxylase, transmembrane	Homo sapiens	62-68
17599380-3	2007	Here, we identify an HIV Env variant in the V4 region of gp120, Asp 386 (D386), that eliminates an N-linked glycosylation site at position 386, enhances viral replication in macrophages, and is present at a higher frequency in AIDS patients with HIV-associated dementia (HAD) compared with non-HAD patients.	Nitrogen	99-100	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	57-62
17909004-2	2007	Recent studies have shown that UGT2B10 is a major enzyme involved in the N-glucuronidation of several tobacco-specific nitrosamines.	Nitrogen	73-74	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	31-38
17909004-3	2007	In the present study, microsomes of UGT2B10-overexpressing HEK293 cells exhibited high N-glucuronidation activity against both nicotine and cotinine with apparent KM"s that were 37- and 3-fold lower than that observed for microsomes of UGT1A4-overexpressing cells against nicotine and cotinine, respectively.	Nitrogen	87-88	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	36-43
17909004-7	2007	These data suggest that UGT2B10 is the major hepatic enzyme involved in nicotine/cotinine glucuronidation and that the UGT2B10*2 variant significantly reduces nicotine- and cotinine-N-glucuronidation formation and plays an important role in nicotine metabolism and elimination.	Nitrogen	182-183	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	24-31
17693598-1	2007	Dal5p has been shown previously to act as an allantoate/ureidosuccinate permease and to play a role in the utilization of certain dipeptides as a nitrogen source in Saccharomyces cerevisiae.	Nitrogen	146-154	allantoate permease	Saccharomyces cerevisiae S288C	0-5
17640631-7	2007	We also show that the nitrogen-containing bisphosphonate-induced effects on p38 phosphorylation occur before accumulation of unprenylated Rap1A or Rac1 activation.	Nitrogen	22-30	RAP1A, member of RAS oncogene family	Homo sapiens	138-143
17428601-6	2007	In addition to N-formylated peptides, numerous unrelated ligands were recently found to interact with FPR and FPRL1.	Nitrogen	15-16	formyl peptide receptor 2	Homo sapiens	110-115
17672512-5	2007	The kinetic specificity constants ( k cat/ K m) for N-acetylation of arylamine environmental contaminants, some of which are associated with bladder cancer risk, were determined with NAT2 and NAT1.	Nitrogen	52-53	N-acetyltransferase 1	Homo sapiens	192-196
17576805-9	2007	Relative contributions of human CYP1A2, CYP2C19, and CYP3A4 to hepatic diuron N-demethylation, based on average abundances of P450 enzymes in human liver microsomes, were approximately 60, 14, and 13%, respectively.	Nitrogen	78-79	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	32-38
17576790-4	2007	UGT2B10 was also more active than UGT1A4 in N-glucuronidation of cotinine (oxidative nicotine metabolite), whereas UGT2B7 exhibited only low nicotine glucuronidation activity and was essentially inactive toward cotinine.	Nitrogen	44-45	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	0-7
17576790-4	2007	UGT2B10 was also more active than UGT1A4 in N-glucuronidation of cotinine (oxidative nicotine metabolite), whereas UGT2B7 exhibited only low nicotine glucuronidation activity and was essentially inactive toward cotinine.	Nitrogen	44-45	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	34-40
17636988-9	2007	In addition, Endo D/H digestion uniquely enabled identification of 23 fucosylated N-glycosylation sites.	Nitrogen	82-83	mannosidase endo-alpha	Homo sapiens	13-17
17643119-2	2007	This structure is the first atomic-resolution view of a nAChR subunit extracellular domain, revealing receptor-specific features such as the main immunogenic region (MIR), the signature Cys-loop and the N-linked carbohydrate chain.	Nitrogen	203-204	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	56-61
19071808-1	2007	A highly selective method for the preconcentration and the determination of nitrogen heterocyclic compounds (NHCs) by solid phase extraction-room temperature phosphorimetry (SPE-RTP) was described.	Nitrogen	76-84	MORN repeat containing 4	Homo sapiens	178-181
17113343-2	2007	In the present work, we systematically investigate how substitution of nitrogen in a cubanoid influence deshielding of carbon and manifest in the chemical shift in NMR spectra calculated using the second order Moller-Plesset (MP2) perturbation level of theory.	Nitrogen	71-79	tryptase pseudogene 1	Homo sapiens	226-229
17451951-5	2007	Synthesis of the analogous cantharidin analogue (19) with incorporation of the amine nitrogen into the heterocycle further increases PP1 (IC(50)=5.9+/-2.2 microM) and PP2A (IC(50)=0.79+/-0.1 microM) inhibition and cell cytotoxicity (GI(50) approximately 3.3 microM).	Nitrogen	85-93	protein phosphatase 2 phosphatase activator	Homo sapiens	167-171
17565660-5	2007	RESULTS: Our study shows that the N-glycosylation of N197 and N232, but not N212, is essential for PPT1"s activity and intracellular transport.	Nitrogen	34-35	palmitoyl-protein thioesterase 1	Homo sapiens	99-103
17285627-6	2007	It is also found that the N-capping motif adopted by the FSD-1 contributes to the stability of the alpha-helix dramatically.	Nitrogen	26-27	fibronectin type III and SPRY domain containing 1	Homo sapiens	57-62
17378593-3	2007	In particular, FT-SERS shows decreasing amounts of surface-bound ClO4- upon oxidation of the ferrocene with decreasing n, while EQCM data show the effective electrode mass increase was consistently higher on the shorter chain SAMs.	Nitrogen	1-2	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	18-22
17197096-1	2007	Neuronal Kv3 voltage-gated K(+) channels have two absolutely conserved N-glycosylation sites.	Nitrogen	0-1	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	9-12
17197096-2	2007	Here, it is shown that Kv3.1, 3.3, and 3.4 channels are N-glycosylated in rat brain.	Nitrogen	56-57	potassium voltage-gated channel subfamily C member 1	Rattus norvegicus	23-28
17197096-8	2007	We suggest that N-glycosylation processing of Kv3 channels is critical for the expression of K(+) currents at the surface of neurons, and perhaps contributes to the pathophysiology of congenital disorders of glycosylation.	Nitrogen	16-17	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	46-49
17450303-1	2007	The forests of the San Bernardino Mountains have been subject to ozone and nitrogen (N) deposition for some 60 years.	Nitrogen	75-83	N-alpha-acetyltransferase 50, NatE catalytic subunit	Homo sapiens	19-22
17477046-1	2007	On the basis of ab initio MP2 and semi-empirical PM3 quantum-chemical calculations the bistability of the nonplanar O=C-N-H fragment in the structure of simple amides and dipeptides is discussed.	Nitrogen	120-121	tryptase pseudogene 1	Homo sapiens	26-29
17052995-1	2007	2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis is initiated by N(2)-hydroxylation, mediated by several cytochromes P450, including CYP1A1.	Nitrogen	86-90	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	154-160
17052995-6	2007	In contrast, PhIP N(2)-hydroxylation activity in lung homogenates of Cyp1a2-null versus WT mice was not decreased.	Nitrogen	18-22	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	69-75
17348860-3	2007	BCATc accounts for 70% of brain BCAT activity, and contributes at least 30% of the nitrogen required for glutamate synthesis.	Nitrogen	83-91	branched chain amino acid transaminase 1	Homo sapiens	0-5
17187761-0	2007	EOS1, whose deletion confers sensitivity to oxidative stress, is involved in N-glycosylation in Saccharomyces cerevisiae.	Nitrogen	77-78	Eos1p	Saccharomyces cerevisiae S288C	0-4
17187761-6	2007	The inhibition of the N-glycosylation of carboxypeptidase Y and invertase activity caused by the addition of tunicamycin was depressed in Delta eos1, suggesting that EOS1 may be involved in N-glycosylation of the cellular proteins.	Nitrogen	22-23	Eos1p	Saccharomyces cerevisiae S288C	144-148
17187761-6	2007	The inhibition of the N-glycosylation of carboxypeptidase Y and invertase activity caused by the addition of tunicamycin was depressed in Delta eos1, suggesting that EOS1 may be involved in N-glycosylation of the cellular proteins.	Nitrogen	22-23	Eos1p	Saccharomyces cerevisiae S288C	166-170
17187761-6	2007	The inhibition of the N-glycosylation of carboxypeptidase Y and invertase activity caused by the addition of tunicamycin was depressed in Delta eos1, suggesting that EOS1 may be involved in N-glycosylation of the cellular proteins.	Nitrogen	190-191	Eos1p	Saccharomyces cerevisiae S288C	144-148
17187761-6	2007	The inhibition of the N-glycosylation of carboxypeptidase Y and invertase activity caused by the addition of tunicamycin was depressed in Delta eos1, suggesting that EOS1 may be involved in N-glycosylation of the cellular proteins.	Nitrogen	190-191	Eos1p	Saccharomyces cerevisiae S288C	166-170
17276344-4	2007	Sxl appears to negatively regulate the pathway by reducing N protein accumulation, and higher levels of N are found in Sxl(-) clones than in adjacent wild-type cells.	Nitrogen	59-60	Sex lethal	Drosophila melanogaster	0-3
17276344-4	2007	Sxl appears to negatively regulate the pathway by reducing N protein accumulation, and higher levels of N are found in Sxl(-) clones than in adjacent wild-type cells.	Nitrogen	104-105	Sex lethal	Drosophila melanogaster	119-122
16838348-8	2007	However, BSO enhanced the N2-induced HO-1 protein level by up to twofold (p &lt; 0.05).	Nitrogen	26-28	heme oxygenase 1	Homo sapiens	37-41
17160180-1	2007	Reaction of the electron-rich, bulky tridentate PNN ligand (PNN=2-di-tert-butylphosphinomethyl-6-diethylaminomethylpyridine) with Ru(PPh3)3Cl2 at 65 degrees C resulted in formation of the mononuclear dinitrogen complex (PNN)Ru(Cl)2N2 (minor) and the N2 bridged Ru(II) dinuclear complex [(PNN)Ru(Cl)2]2(micro-N2) (major).	Nitrogen	231-233	protein phosphatase 4 catalytic subunit	Homo sapiens	133-137
17085048-0	2007	Nitrogen-containing flavonoids as CDK1/Cyclin B inhibitors: design, synthesis, and biological evaluation.	Nitrogen	0-8	cyclin dependent kinase 1	Homo sapiens	34-38
17085048-1	2007	A novel series of nitrogen-containing flavonoids 5a-l, 6a,b, and 7a,b were designed and synthesized as cyclin-dependent kinases (CDKs) inhibitors.	Nitrogen	18-26	cyclin dependent kinase 1	Homo sapiens	129-133
17636465-3	2007	PPh4[IrCl5(NO)] forms a crystal in which the [IrCl5(NO)]- anions are in a curious wire-like linear arrangement, in which the distance between the N--O moiety of one anion and the trans chloride of the upper one nearby is only 2.8 A.	Nitrogen	11-12	potassium two pore domain channel subfamily K member 3	Homo sapiens	0-4
17020955-7	2007	In human liver microsomes, involvement of CYP2D6, CYP1A2, CYP2C9, and CYP2C19 in diphenhydramine N-demethylation was confirmed by using P450 isozyme-specific inhibitors.	Nitrogen	97-98	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	50-56
17020955-7	2007	In human liver microsomes, involvement of CYP2D6, CYP1A2, CYP2C9, and CYP2C19 in diphenhydramine N-demethylation was confirmed by using P450 isozyme-specific inhibitors.	Nitrogen	97-98	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	58-64
17050611-7	2007	PRM-A has a high genetic barrier, since more than five N-glycosylation site deletions in gp120 are required to afford moderate drug resistance.	Nitrogen	55-56	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	89-94
17200572-7	2007	When TOR is inactivated by rapamycin treatment or nitrogen starvation, downstream effectors of TOR such as the serine/threonine protein kinase NPR1 and the TAP42 interacting protein TIP41 are dephosphorylated in a SIT4-dependent manner.	Nitrogen	50-58	Tap42p	Saccharomyces cerevisiae S288C	156-161
17200572-7	2007	When TOR is inactivated by rapamycin treatment or nitrogen starvation, downstream effectors of TOR such as the serine/threonine protein kinase NPR1 and the TAP42 interacting protein TIP41 are dephosphorylated in a SIT4-dependent manner.	Nitrogen	50-58	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	214-218
16595132-3	2006	We found that CD-1 mice treated with FA developed acute renal failure characterized by increased blood urea nitrogen, necrosis, and apoptosis of tubular epithelial cells.	Nitrogen	108-116	CD1 antigen complex	Mus musculus	14-18
16824775-6	2006	The major result of this study is the identification of intra-molecular interactions, whether it is at B3LYP/cc-pVDZ or at MP2/cc-pVDZ, as the dominant stabilizing factor for the large all-nitrogen cage.	Nitrogen	189-197	tryptase pseudogene 1	Homo sapiens	123-126
17076494-3	2006	The reaction of styrene on NH- and N-covered Ag surface appears to yield 2-phenylaziridine and benzonitrile, with additional products HCN and NH3.	Nitrogen	27-28	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	134-137
16970389-5	2006	The analysis of the singlet potential energy surface, and the corresponding computational kinetic study, shows that for the reaction of excited nitrogen atoms with methyl radicals, the preferred product from the kinetic point of view is also H2CN+H, but in this case production of HCN is significant (with branching ratios around 0.185).	Nitrogen	144-152	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	281-284
16960360-1	2006	Glutamine synthetase (GS) is a key enzyme for nitrogen assimilation.	Nitrogen	46-54	CYME_CMI233C	Cyanidioschyzon merolae strain 10D	0-20
16960360-1	2006	Glutamine synthetase (GS) is a key enzyme for nitrogen assimilation.	Nitrogen	46-54	CYME_CMI233C	Cyanidioschyzon merolae strain 10D	22-24
16969073-1	2006	An N-glycosylated 60-kDa PV-1 protein that binds heparin was detected in mouse lung from a single mRNA transcript.	Nitrogen	3-4	plasmalemma vesicle associated protein	Mus musculus	25-29
16969078-1	2006	The PV-1 protein is endogenously expressed from a single mRNA in the mouse pancreatic MS-1 endothelial cell line as a 60-kDa N-glycosylated and 50-kDa non-glycosylated protein that form DTT sensitive oligomers.	Nitrogen	59-60	plasmalemma vesicle associated protein	Mus musculus	4-8
16871372-6	2006	Thus, endomannosidase does not discriminate the folding state of the substrate and provides a back-up mechanism for completion of N-glycosylation of endoplasmic reticulum-escaped glucosylated glycoproteins.	Nitrogen	130-131	mannosidase endo-alpha	Homo sapiens	6-21
16798095-9	2006	All these findings led us to conclude that interactions between N-SH3 of p47phox and PPII helix, which is formed by cytoplasmic region of p22phox, may play a significant role in the activation of the NADPH oxidase.	Nitrogen	64-65	cytochrome b-245 alpha chain	Homo sapiens	138-145
19719619-5	2003	Thus, despite optimal environmental conditions and genetic potential for denitrification, the blooms of filamentous nitrogen-fixing cyanobacteria must be seen solely as a source, and not as a sink of nitrogen in the Baltic Sea.	Nitrogen	116-124	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	223-226
12828642-0	2003	Arg82p is a bifunctional protein whose inositol polyphosphate kinase activity is essential for nitrogen and PHO gene expression but not for Mcm1p chaperoning in yeast.	Nitrogen	95-103	inositol polyphosphate multikinase	Saccharomyces cerevisiae S288C	0-6
12828642-5	2003	Arg82p and Kcs1p are required for activation of NCR-regulated genes in response to nitrogen availability, mainly through Nil1p, and for repression of PHO genes by phosphate.	Nitrogen	83-91	inositol polyphosphate multikinase	Saccharomyces cerevisiae S288C	0-6
14587334-8	2003	The primary production in a considerable portion of the Yellow Sea and the East China Sea might be limited by phosphate rather than nitrogen.	Nitrogen	132-140	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	63-66
14587334-8	2003	The primary production in a considerable portion of the Yellow Sea and the East China Sea might be limited by phosphate rather than nitrogen.	Nitrogen	132-140	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	86-89
12846977-3	2003	The detection of tyrosine-nitrated alpha-syn signifies the formation of reactive nitrogen species capable of both radical and electrophilic attack on aromatic residues as well as nucleophilic additions and oxidations.	Nitrogen	81-89	synuclein alpha	Homo sapiens	35-44
12846977-6	2003	Posttranslational modifications of alpha-syn by reactive nitrogen species inhibits fibril formation and results in urea- and SDS- insoluble, protease-resistant alpha-syn aggregates that maybe responsible for cellular toxicity.	Nitrogen	57-65	synuclein alpha	Homo sapiens	35-44
12846977-6	2003	Posttranslational modifications of alpha-syn by reactive nitrogen species inhibits fibril formation and results in urea- and SDS- insoluble, protease-resistant alpha-syn aggregates that maybe responsible for cellular toxicity.	Nitrogen	57-65	synuclein alpha	Homo sapiens	160-169
12776183-2	2003	N-glycosylation is initiated by the oligosaccharyl transferase complex and O-mannosylation is initiated by distinct O-mannosyltransferase complexes of the protein mannosyl transferase Pmt1/Pmt2 and Pmt4 families.	Nitrogen	0-1	dolichyl-phosphate-mannose-protein mannosyltransferase	Saccharomyces cerevisiae S288C	198-202
12776183-4	2003	In addition, it is shown that O-mannosylation by Pmt4 prevents N-glycosylation by blocking the hydroxy amino acid of the single N-glycosylation site present in Ccw5.	Nitrogen	63-64	dolichyl-phosphate-mannose-protein mannosyltransferase	Saccharomyces cerevisiae S288C	49-53
12776183-4	2003	In addition, it is shown that O-mannosylation by Pmt4 prevents N-glycosylation by blocking the hydroxy amino acid of the single N-glycosylation site present in Ccw5.	Nitrogen	128-129	dolichyl-phosphate-mannose-protein mannosyltransferase	Saccharomyces cerevisiae S288C	49-53
12776183-5	2003	These data prove that the O- and N-glycosylation machineries compete for Ccw5; therefore O-mannosylation by Pmt4 precedes N-glycosylation.	Nitrogen	33-34	dolichyl-phosphate-mannose-protein mannosyltransferase	Saccharomyces cerevisiae S288C	108-112
12820961-4	2003	In contrast, Tap42 inactivation, as does inactivation of the protein phosphatases Sit4 and Pph21/22, blocks rapamycin induction of nitrogen discrimination pathway genes.	Nitrogen	131-139	Tap42p	Saccharomyces cerevisiae S288C	13-18
12820961-4	2003	In contrast, Tap42 inactivation, as does inactivation of the protein phosphatases Sit4 and Pph21/22, blocks rapamycin induction of nitrogen discrimination pathway genes.	Nitrogen	131-139	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	82-86
12626425-8	2003	In nonreducing SDS-PAGE, these two human HARE species migrated at approximately 190 kDa and approximately 315 kDa; both proteins are approximately 15 kDa larger than the corresponding rat HAREs, although the de-N-glycosylated core proteins are essentially the same mass.	Nitrogen	211-212	stabilin 2	Homo sapiens	41-45
12929581-0	2003	N-acetyltransferase is involved in gypenosides-induced N-acetylation of 2-aminofluorene and DNA adduct formation in human cervix epidermoid carcinoma cells (Ca Ski).	Nitrogen	0-1	SKI proto-oncogene	Homo sapiens	160-163
12691569-2	2003	Low temperature infrared spectra of light induced metastable states MS1 and MS2 of the nitroprusside anion in Na(2)[Fe(CN)(5)NO].2H(2)O, isotopically normal and substituted with (15)NO and N(18)O, are presented and discussed.	Nitrogen	110-111	MS2	Homo sapiens	76-79
12529169-0	2003	Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3.	Nitrogen	0-8	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	147-151
12529169-9	2003	Furthermore, rapamycin causes similar CIS2 activation, indicating that the target of rapamycin signalling pathway controls CIS2 expression via Gln3 and Nil1 in nitrogen-starved cells.	Nitrogen	160-168	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	143-147
12667607-4	2003	In the alg1 and alg2 mutants, complemented with MPG1 gene, N-glycosylation of invertase was in part restored, to a degree comparable to that of the wild-type control.	Nitrogen	59-60	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	7-11
12721102-21	2003	Regarding the relative expression of various CYPs in human liver, the obtained results indicate that CYP1A2 and CYP3A4 are the main isoforms responsible for 5-sulphoxidation, while CYP1A2 and CYP2C19 are the basic isoforms that catalyse N-demethylation of promazine in human liver.	Nitrogen	237-238	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	101-107
12632065-8	2003	In contrast, addition of 50 micro M NS-398 to COX-2 non-expressing PLC/PRF/5 cells resulted in only a mild reduction of cell proliferation.	Nitrogen	36-38	heparan sulfate proteoglycan 2	Homo sapiens	67-70
12525494-7	2003	However, for only SER33, and not SER3, expression was regulated in relation to the available nitrogen source in a coordinated fashion with SER1 and SER2.	Nitrogen	93-101	O-phospho-L-serine:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	139-143
12525494-7	2003	However, for only SER33, and not SER3, expression was regulated in relation to the available nitrogen source in a coordinated fashion with SER1 and SER2.	Nitrogen	93-101	phosphoserine phosphatase	Saccharomyces cerevisiae S288C	148-152
12633091-0	2003	Transition metal-catalyzed regio- and stereoselective aminobromination of olefins with TsNH2 and NBS as nitrogen and bromine sources.	Nitrogen	104-112	nibrin	Homo sapiens	97-100
12617658-0	2003	Structural model for an alkaline form of ferricytochrome C. An (15)N-enriched sample of the yeast iso-1-ferricytochrome c triple variant (Lys72Ala/Lys79Ala/Cys102Thr) in an alkaline conformation was examined by NMR spectroscopy.	Nitrogen	67-68	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	98-103
12620851-3	2003	A pro3 ure2 strain expressing a PGK1 promoter-driven PUT2 allele encoding Delta(1)-pyrroline-5-carboxylate dehydrogenase lacking a mitochondrial targeting sequence produced significant cytoplasmic activity, accumulated twice as much intracellular glutamate, and produced twice as much cell mass as the parent when grown anaerobically on limiting arginine as sole nitrogen source.	Nitrogen	363-371	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	53-57
12663521-2	2003	Based on in vitro studies with rats and humans, CYP1A2 is believed to be the primary enzyme responsible for N(2)-hydroxylation, the initial step in the metabolic activation of PhIP.	Nitrogen	108-112	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	48-54
12446689-9	2003	Intriguingly, removal of the negative charge from either 216 or 301 produced enzymes (E216A, E216K, and D301Q) with elevated levels (50-75-fold) of catalytic activity toward diclofenac, a carboxylate-containing CYP2C9 substrate that lacks a basic nitrogen atom.	Nitrogen	247-255	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	211-217
12540831-6	2003	Alteration in the extent of phosphorylation at Ser-353 and Ser-357 could be easily assessed and quantitated both in wild-type yeast cells treated with rapamycin and in cells lacking the SIT4 phosphatase responsible for dephosphorylating nitrogen permease reactivator protein.	Nitrogen	237-245	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	186-190
12527303-6	2003	The IgG-Fc is a homodimer of N-linked glycopeptide chains comprised of two immunoglobulin domains (Cgamma2, Cgamma3) that dimerise via inter-heavy chain disulphide bridges at the N-terminal region and non-covalent interactions between the C-terminal Cgamma3 domains.	Nitrogen	29-30	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	108-115
12489124-1	2003	The role of Gln3p, Nil1p, Dal80p and Ure2p in the nitrogen regulation of ASP3, which codes for the periplasmic Saccharomyces cerevisiae asparaginase II, was investigated.	Nitrogen	50-58	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	12-17
12520306-5	2003	Under conditions of limiting nitrogen, loss of Srb10 protein and kinase activity occurs, with a corresponding loss of Ste12 phosphorylation.	Nitrogen	29-37	cyclin-dependent serine/threonine protein kinase SSN3	Saccharomyces cerevisiae S288C	47-52
12520306-8	2003	This indicates that Srb10 controls Ste12 activity for filamentous growth in response to nitrogen limitation and is consistent with the hypothesis that Srb10 regulates gene-specific activators in response to physiological signals to coordinate gene expression with growth potential.	Nitrogen	88-96	cyclin-dependent serine/threonine protein kinase SSN3	Saccharomyces cerevisiae S288C	20-25
14696973-3	2003	OA sequence analysis also demonstrated 13 putative N-glycosylation sites suggestive of a heavily glycosylated protein.	Nitrogen	51-52	glycoprotein nmb	Rattus norvegicus	0-2
14503661-6	2003	The in vitro intrinsic clearance (CL(int), ml/min/mg cytosolic protein) of N-acetyltransferase (NAT) activities of dog liver cytosol towards SM-18400 and hepatic N-acetylation clearance (CL(NAc), ml/min/kg body weight) estimated by well-stirred model were both only 5% of the respective rat value, well reflecting the relative in vivo CL(NAc)/CL(tot) ratios.	Nitrogen	75-76	synuclein alpha	Homo sapiens	187-194
14503661-6	2003	The in vitro intrinsic clearance (CL(int), ml/min/mg cytosolic protein) of N-acetyltransferase (NAT) activities of dog liver cytosol towards SM-18400 and hepatic N-acetylation clearance (CL(NAc), ml/min/kg body weight) estimated by well-stirred model were both only 5% of the respective rat value, well reflecting the relative in vivo CL(NAc)/CL(tot) ratios.	Nitrogen	75-76	synuclein alpha	Homo sapiens	335-342
12524480-2	2003	Glutamate dehydrogenase (GDH) is a mitochondrial enzyme that catalyzes both the reversible conversion of ammonium nitrogen into organic nitrogen (glutamate production) and the oxidative deamination of glutamate resulting in 2-oxoglutarate.	Nitrogen	114-122	glutamate dehydrogenase 1	Homo sapiens	0-23
12524480-2	2003	Glutamate dehydrogenase (GDH) is a mitochondrial enzyme that catalyzes both the reversible conversion of ammonium nitrogen into organic nitrogen (glutamate production) and the oxidative deamination of glutamate resulting in 2-oxoglutarate.	Nitrogen	114-122	glutamate dehydrogenase 1	Homo sapiens	25-28
12489987-2	2002	Both, gp120 and CXCR4 are subject to N-glycosylation.	Nitrogen	37-38	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	6-11
12433823-10	2002	In conclusion, the involvement of UGT1A1 and UGT1A9 as well as UGT1A4 in nicotine and cotinine N-glucuronidations in human liver microsomes was suggested, although the contributions of each UGT isoform could not be determined conclusively.	Nitrogen	95-96	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	63-69
16845394-3	2006	To determine whether the extended conformation has higher affinity for ligand, we introduced an N-glycosylation site to "wedge open" the interface between the lectin and EGF-like domains of P-selectin.	Nitrogen	96-97	selectin P	Homo sapiens	190-200
16813429-5	2006	The [SNO][NN] mixed-ligand system was applied in the synthesis of the oxorhenium complex 5 in which the 1-(2-methoxyphenyl)piperazine moiety, a fragment of the true 5-HT1A antagonist WAY 100635, has been incorporated in the NN bidentate ligand (NN is N-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}pyridine-2-aldimine).	Nitrogen	10-12	5-hydroxytryptamine receptor 1A	Homo sapiens	165-171
16575570-3	2006	The resulting shortage of available nitrogen sources induces the Ntr response, which involves induction of the glnALG, glnK-amtB, dppABCDF, and oppABCDF operons as well as the genes coding for outer membrane proteins, porins OmpA and OmpC, and proteases OmpP and OmpT.	Nitrogen	36-44	outer membrane protein A	Escherichia coli str. K-12 substr. MG1655	225-229
16575570-3	2006	The resulting shortage of available nitrogen sources induces the Ntr response, which involves induction of the glnALG, glnK-amtB, dppABCDF, and oppABCDF operons as well as the genes coding for outer membrane proteins, porins OmpA and OmpC, and proteases OmpP and OmpT.	Nitrogen	36-44	outer membrane porin C	Escherichia coli str. K-12 substr. MG1655	234-238
16575570-4	2006	The increased uptake of peptides facilitated by the products of dppABCDF, oppABCDF, ompA, ompC, ompP, and ompT alleviates nitrogen limitation of the growth.	Nitrogen	122-130	outer membrane protein A	Escherichia coli str. K-12 substr. MG1655	84-88
16575570-4	2006	The increased uptake of peptides facilitated by the products of dppABCDF, oppABCDF, ompA, ompC, ompP, and ompT alleviates nitrogen limitation of the growth.	Nitrogen	122-130	outer membrane porin C	Escherichia coli str. K-12 substr. MG1655	90-94
16792699-0	2006	Characterization of N-glycosylation consensus sequences in the Kv3.1 channel.	Nitrogen	20-21	potassium voltage-gated channel subfamily C member 1	Rattus norvegicus	63-68
16792699-2	2006	Here we have characterized two consensus N-glycosylation sequences of a voltage-gated K+ channel (Kv3.1).	Nitrogen	41-42	potassium voltage-gated channel subfamily C member 1	Rattus norvegicus	98-103
16792699-5	2006	To demonstrate N-glycosylation of wild-type Kv3.1 in Sf9 cells, cells were treated with tunicamycin.	Nitrogen	15-16	potassium voltage-gated channel subfamily C member 1	Rattus norvegicus	44-49
16792699-11	2006	These results demonstrate that the S1-S2 linker is topologically extracellular, and that N-glycosylation influences the opening of the voltage-dependent gate of Kv3.1.	Nitrogen	89-90	potassium voltage-gated channel subfamily C member 1	Rattus norvegicus	161-166
16478442-1	2006	Distinct domains within the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) proteins, STX1A (syntaxin 1A) and SNAP-25 (synaptosome-associated protein-25 kDa), regulate hormone secretion by their actions on the cell"s exocytotic machinery, as well as voltage-gated Ca2+ and K+ channels.	Nitrogen	29-30	synaptosome associated protein 25	Homo sapiens	157-194
12475959-10	2002	Disruption of the N-glycosylation sites in each of the DMT1 isoforms affects their polarized distribution into the apical plasma membrane but not their correct endosomal localization.	Nitrogen	18-19	solute carrier family 11 member 2	Homo sapiens	55-59
2689174-3	1989	Cystatin C was found to be composed of 120 amino acids and to contain a potential site for N-linked glycosylation.	Nitrogen	91-92	cystatin C	Rattus norvegicus	0-10
12417748-2	2002	In an effort to define how different nitrogen sources control Gap1p sorting, we find that mutations in GDH1 and GLN1 that decrease the flux through the glutamate and glutamine synthesis pathways result in increased Gap1p sorting to the plasma membrane.	Nitrogen	37-45	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	103-107
12417748-2	2002	In an effort to define how different nitrogen sources control Gap1p sorting, we find that mutations in GDH1 and GLN1 that decrease the flux through the glutamate and glutamine synthesis pathways result in increased Gap1p sorting to the plasma membrane.	Nitrogen	37-45	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	112-116
16706410-13	2006	In addition, the nitrogen atoms in 2-4 are predicted to attain basicities in the range 920-950 kJ/mol, making them basic enough to be the preferred site for hydrogen bonding in the Pin-1 active site, in support of the proposed mechanism for PPIases.	Nitrogen	17-25	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	181-186
2552998-1	1989	Herpes simplex virus type-1 glycoprotein C (gC1) contains several O-linked oligosaccharides clustered near N-linked chains, and Pronase digestion produces glycopeptides carrying both oligosaccharide types.	Nitrogen	107-108	solute carrier family 25 member 22	Homo sapiens	44-47
16580682-5	2006	Functionally, targeted disruption of the STM1 gene results in rapamycin hypersensitivity and a defect in recovery following nitrogen starvation and replenishment.	Nitrogen	124-132	Stm1p	Saccharomyces cerevisiae S288C	41-45
16480962-6	2006	Only UGT1A4 catalyzed the N-linked glucuronidation of 4-HO-TAM among recombinant human UGT isoforms (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A10, UGT2B4, UGT2B7, UGT2B15, and UGT2B17) expressed in insect cells.	Nitrogen	26-27	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	5-11
16408199-4	2006	Mabs directed against an N-glycosylation-dependent epitope within the EGF-domains (CD97(EGF)) did not bind to normal SMC.	Nitrogen	25-26	epidermal growth factor	Homo sapiens	83-93
16408199-12	2006	As expected, CD97(EGF)-positive SMC tumors expressed partly N-glycosylated CD97.	Nitrogen	60-61	adhesion G protein-coupled receptor E5	Homo sapiens	13-17
16408199-12	2006	As expected, CD97(EGF)-positive SMC tumors expressed partly N-glycosylated CD97.	Nitrogen	60-61	adhesion G protein-coupled receptor E5	Homo sapiens	75-79
16555885-0	2006	Estimated MP2 and CCSD(T) interaction energies of n-alkane dimers at the basis set limit: comparison of the methods of Helgaker et al.	Nitrogen	15-16	tryptase pseudogene 1	Homo sapiens	10-13
12413094-4	2002	In the silage extracts, mean proportions of PLP-N, SP-N, and FAA-N in the NAN were 30, 52, and 18%, respectively, whereas in the fresh grass the corresponding values were 67, 20, and 13%.	Nitrogen	48-49	proteolipid protein 1	Bos taurus	44-47
12138100-11	2002	These combined results indicate that the synergistic effect of ST8Sia II and ST8Sia IV is caused by: 1) the ability of ST8Sia IV to add polysialic acid to oligosialic acid formed by ST8Sia II, 2) the potential of ST8Sia IV to act on more antennas of N-glycans than ST8Sia II, and 3) the ability of ST8Sia II and ST8Sia IV in combination to act on the fifth and sixth N-glycosylation sites of NCAM.	Nitrogen	250-251	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	Homo sapiens	63-72
12199704-7	2002	Three N-glycopeptides of ZPA, containing an N-glycosylation site at Asn83, Asn191 and Asn527, respectively, were obtained from endo-beta-Galactosidase-digested ZPA.	Nitrogen	6-7	galactosidase beta 1	Bos taurus	132-150
12213788-4	2002	hDK1 is capable of complementing the growth defect, elevating DK activity, and consequently increasing Dol-P levels in vivo and restoring normal N-glycosylation of carboxypeptidase Y at the restrictive temperature in the temperature-sensitive mutant sec59-1.	Nitrogen	145-146	dolichol kinase	Homo sapiens	0-4
12130726-15	2002	Furthermore, results obtained with the N-methyl-exo-THPO prodrug demonstrate the feasibility of developing a glial-selective GABA uptake inhibitor with systemic bioavailability.	Nitrogen	39-40	5'-3' exoribonuclease 1	Mus musculus	48-51
12137964-8	2002	During concomitant infusion of the specific competitive NOP receptor antagonist [Nphe(1)]nociceptin(1-13)NH(2) 10(-6) M, the effect of N/OFQ is abolished (6+/-11%; p&lt;0.05 vs. GIP and N/OFQ) while the opiate receptor antagonist naloxone 10(-6) M has no significant effect (-32+/-9%; ns vs. GIP and N/OFQ).	Nitrogen	56-57	prepronociceptin	Rattus norvegicus	89-99
2552998-5	1989	Since there is evidence that the processing of N-linked chains up to Man8GlcNAc2 involves enzymes located in the rough endoplasmic reticulum, current results strongly suggest that gC1 acquires O-linked N-acetylgalactosamine before the glycoprotein routing to the Golgi apparatus.	Nitrogen	47-48	solute carrier family 25 member 22	Homo sapiens	180-183
16407218-3	2006	We isolated the serum protease inhibitor alpha(2) macroglobulin (alpha2M), a heavily glycosylated thiol ester protein (TEP) composed of four identical 180-kDa subunits, each of which has eight N-linked glycosylation sites.	Nitrogen	193-194	alpha-2-macroglobulin	Homo sapiens	41-63
16407218-3	2006	We isolated the serum protease inhibitor alpha(2) macroglobulin (alpha2M), a heavily glycosylated thiol ester protein (TEP) composed of four identical 180-kDa subunits, each of which has eight N-linked glycosylation sites.	Nitrogen	193-194	alpha-2-macroglobulin	Homo sapiens	65-72
12097163-1	2002	The secretion of N-linked glycosylated alpha-lactalbumin was much higher in the expression system of yeast Pichia pastoris carrying goat alpha-lactalbumin cDNA than in mammalian milk.	Nitrogen	17-18	alpha-lactalbumin	Capra hircus	39-56
12097163-1	2002	The secretion of N-linked glycosylated alpha-lactalbumin was much higher in the expression system of yeast Pichia pastoris carrying goat alpha-lactalbumin cDNA than in mammalian milk.	Nitrogen	17-18	alpha-lactalbumin	Capra hircus	137-154
2520824-0	1989	Identification, cloning, and sequence analysis of the nitrogen regulation gene ntrC of Agrobacterium tumefaciens C58.	Nitrogen	54-62	nitrogen regulation protein NR(I)	Agrobacterium fabrum str. C58	79-83
12097163-5	2002	On the other hand, mutant D46N with another N-glycosylation signal site at position 46 only secreted N-linked glycosylated alpha-lactalbumin, i.e. not the nonglycosylated protein.	Nitrogen	29-30	alpha-lactalbumin	Capra hircus	123-140
12097163-5	2002	On the other hand, mutant D46N with another N-glycosylation signal site at position 46 only secreted N-linked glycosylated alpha-lactalbumin, i.e. not the nonglycosylated protein.	Nitrogen	44-45	alpha-lactalbumin	Capra hircus	123-140
12354539-3	2002	In comparison with the control plasmid and the IL-4-encoding plasmid, the IFN-gamma-encoding plasmid promoted increased blood urea nitrogen values and reduced the survival rate, and these changes were accompanied by the development of anti-nuclear antibody.	Nitrogen	131-139	interleukin 4	Mus musculus	47-51
16289855-0	2006	Novel tricyclic quinazolinimines and related tetracyclic nitrogen bridgehead compounds as cholinesterase inhibitors with selectivity towards butyrylcholinesterase.	Nitrogen	57-65	butyrylcholinesterase	Homo sapiens	90-104
16289855-1	2006	Tetracyclic nitrogen bridgehead compounds, dibenzodiazecines and tricyclic quinazolinimines, in which the size of the alicyclic ring system and the length of the alkyl chain between the quinazolinimine moiety and a phenyl ring connected to the imine nitrogen atom were changed systematically, were synthesized and their ability to inhibit acetyl- and butyrylcholinesterase (AChE/BChE), respectively, was evaluated.	Nitrogen	12-20	butyrylcholinesterase	Homo sapiens	379-383
2671705-3	1989	Regarding inactivation, the pso4-1 mutant is also sensitive to mono- (HN1) or bi-functional (HN2) nitrogen mustards, it is slightly sensitive to 254 nm UV radiation (UV), and shows nearly normal sensitivity to 3-carbethoxypsoralen (3-CPs) photoaddition or methyl methanesulfonate (MMS).	Nitrogen	98-106	E3 ubiquitin-protein ligase PRP19	Saccharomyces cerevisiae S288C	28-32
16542136-3	2006	The rapid amplification of cDNA ends (RACE) method was used to obtain a cDNA of bovine IL-17 (BoIL-17) containing a 462-bp open reading frame (ORF) encoding a protein of 153 amino acids (aa) with a molecular mass of 17.2 kDa, a 23-residue NH(2)-terminal signal peptide, a single potential N-linked glycosylation site, and 6 cysteine residues.	Nitrogen	29-30	interleukin 17A	Bos taurus	87-92
12072497-8	2002	Sequence analysis of the V1/V2 and V3 regions of the viral envelope protein gp120 revealed that the more efficient CXCR4 usage of the later isolate might be caused by an additional potential N-glycosylation site in the V1/V2 loop.	Nitrogen	191-192	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	76-81
2571477-4	1989	Reconstituted rat P-450 UT-A exhibited a high rate of N-oxidation (15 nmol min-1 nmol P-450-1) which is almost 3-fold higher than the turnover number observed with male rat liver microsomes.	Nitrogen	54-55	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	18-28
12115478-1	2002	Muc4 (also called sialomucin complex), the rat homolog of human MUC4, is a heterodimeric glycoprotein complex that consists of a peripheral O-glycosylated mucin subunit, ASGP-1, tightly but noncovalently linked to a N-glycosylated transmembrane subunit, ASGP-2.	Nitrogen	216-217	mucin 4, cell surface associated	Rattus norvegicus	0-4
12115513-6	2002	PCNA expression was downregulated by NS-398 in a dose-independent manner.	Nitrogen	37-39	proliferating cell nuclear antigen	Homo sapiens	0-4
12201212-2	2002	We have demonstrated that reduced nitrogen balance is related to changes in serum IGF-I levels but not serum growth hormone levels in pregnant rats.	Nitrogen	34-42	insulin-like growth factor 1	Rattus norvegicus	82-87
12009910-7	2002	The tetracopper clusters bound by Ace1 and Mac1 differ in that the Ace1 cluster is coordinated entirely by cysteinyl thiolate, whereas the cysteine-deficient Mac1 cluster appears to consist of a Cu(4)(S-Cys)(5)(N-His) cluster with a bridging histidyl-derived nitrogen.	Nitrogen	259-267	Cup2p	Saccharomyces cerevisiae S288C	34-38
16446829-1	2006	A copper(I) complex with new N2S thiol ligand transforms to a multicopper(I) cluster, [(L(S-))6Cu(I)13(S2-)2]3+ (1); its X-ray structure exhibiting mu4-sulfido and mu3-thiolato coordination is presented and compared to other cuprous thiolato/sulfido clusters including that observed in the copper enzyme nitrous oxide reductase.	Nitrogen	29-32	adaptor related protein complex 4 subunit mu 1	Homo sapiens	148-151
16483201-4	2006	In the frequency region examined in this experimental study we only observe one of these, corresponding to the salt binding to the nitrogen end of the HCN molecule.	Nitrogen	131-139	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	151-154
16526560-6	2006	This suggest that for TLP in humans, (i) N-acetylation represents only a relatively small fraction of its total elimination (about one-fourth in fast acetylators and much less in slow acetylators), (ii) acetylation is about eight-twelve times faster in fast and three-six times faster in intermediate acetylators than in slow acetylators, and (iii) the N-acetyl metabolite is eliminated faster than the parent TLP.	Nitrogen	41-42	cysteine rich protein 3	Homo sapiens	22-25
16526560-6	2006	This suggest that for TLP in humans, (i) N-acetylation represents only a relatively small fraction of its total elimination (about one-fourth in fast acetylators and much less in slow acetylators), (ii) acetylation is about eight-twelve times faster in fast and three-six times faster in intermediate acetylators than in slow acetylators, and (iii) the N-acetyl metabolite is eliminated faster than the parent TLP.	Nitrogen	353-354	cysteine rich protein 3	Homo sapiens	22-25
16321355-0	2006	Site-specific N-glycosylation analysis of human plasma ceruloplasmin using liquid chromatography with electrospray ionization tandem mass spectrometry.	Nitrogen	14-15	ceruloplasmin	Homo sapiens	55-68
11877405-11	2002	Collectively, our results demonstrate that: 1) MPO and EPO contribute to tyrosine nitration in vivo; 2) the major reactive nitrogen species formed by leukocyte peroxidase-catalyzed oxidation of NO(2)(-) is the one-electron oxidation product, (*)NO(2); 3) as a minor reaction, peroxidases may also catalyze the two-electron oxidation of NO(2)(-), producing a ONOO(-)-like product.	Nitrogen	123-131	erythropoietin	Mus musculus	55-58
2571477-7	1989	Rabbit antibody to rat P-450 UT-A inhibited the senecionine-N-oxidation activity of untreated male rat liver microsomes by 60%, with lesser inhibition of DHP production.	Nitrogen	60-61	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	23-33
2570348-5	1989	Increased accumulation of GLN1 mRNA was observed within 5 min after a shift from glutamine to glutamate as the nitrogen source.	Nitrogen	111-119	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	26-30
12030840-2	2002	It has been suggested that, in liver from animals not treated with a cytochrome P450 (CYP) inducer, hepatic CYP1A2 is the major P450 involved in N-hydroxylation.	Nitrogen	145-146	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	108-114
16415180-10	2006	These results show that while the Polzeta pathway is generally required for translesion synthesis and mutagenesis of the (+)- and (-)-trans-anti-BPDE-N2-dG DNA adducts, Poleta, Polzeta and Rev1 together are required for G--&gt;T transversion mutations, a major type of mutagenesis induced by these lesions.	Nitrogen	150-152	deoxycytidyl transferase	Saccharomyces cerevisiae S288C	189-193
2570348-7	1989	The level of GLN1 transcript was reduced by approximately 75% within 5 min following glutamine addition to the cells growing with glutamate as nitrogen source.	Nitrogen	143-151	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	13-17
2722801-0	1989	Effect of inhibiting N-glycosylation on the stability and binding activity of the low density lipoprotein receptor.	Nitrogen	21-22	low density lipoprotein receptor	Homo sapiens	82-114
16532746-7	2006	The oxygen/nitrate return sludge model block predicts a 10% improvement of N removal performance under dynamic conditions, and might be the better modelling option for ASM1 plants: it is computationally more efficient and it will not overrate the importance of decay processes in the settler.	Nitrogen	75-76	H19 imprinted maternally expressed transcript	Homo sapiens	168-172
11867635-6	2002	All three potential N-glycosylation sites in M2BP-1,2 and all four in M2BP-3,4 were found to be occupied.	Nitrogen	20-21	galectin 3 binding protein	Homo sapiens	70-74
2722801-8	1989	This indicates that there is a relationship between N-glycosylation and the ligand binding activity of the LDL receptor.	Nitrogen	52-53	low density lipoprotein receptor	Homo sapiens	107-119
16279779-3	2005	Pro-1 was discovered to form a bifurcated hydrogen bond between its protonated nitrogen and carboxylate oxygens of E-ligands and Tyr-36.	Nitrogen	79-87	lamin A/C	Homo sapiens	0-5
2638155-5	1989	WKYs, however, displayed reductions in SBP and HR when exposed to either nitrous oxide or nitrogen.	Nitrogen	90-98	spermine binding protein	Rattus norvegicus	39-42
16425361-7	2005	NS also increased gastric glutathione content (GSH), enzymatic activities of gastric superoxide dismutase (SOD) and glutathione-S-transferase (GST).	Nitrogen	0-2	hematopoietic prostaglandin D synthase	Rattus norvegicus	116-141
16425361-7	2005	NS also increased gastric glutathione content (GSH), enzymatic activities of gastric superoxide dismutase (SOD) and glutathione-S-transferase (GST).	Nitrogen	0-2	hematopoietic prostaglandin D synthase	Rattus norvegicus	143-146
11978110-8	2002	Preliminary X-ray and FAB mass spectroscopic data of 2 have supported the formation of a heterocyclic moiety by a ring closure reaction involving a N-S bond.	Nitrogen	148-149	FA complementation group B	Homo sapiens	22-25
12016157-3	2002	This study examined the urinary excretion of N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine-the major human urinary N-oxidation metabolite of PhIP-and determined its relationship to individual activity levels of cytochrome P4501A2 (CYP1A2) and N-acetyltransferase (NAT2).	Nitrogen	45-46	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	250-268
12016157-3	2002	This study examined the urinary excretion of N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine-the major human urinary N-oxidation metabolite of PhIP-and determined its relationship to individual activity levels of cytochrome P4501A2 (CYP1A2) and N-acetyltransferase (NAT2).	Nitrogen	45-46	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	270-276
3418713-3	1988	Using N-methylacetamide as a model peptide, the free energies of the following processes were determined; (1) formation of the C=O ... H-N bond in water, (2) formation of the C=O ... N-N bond in CCl4, and (3) transfer of N-methylacetamide from water to CCl4.	Nitrogen	6-7	C-C motif chemokine ligand 4	Homo sapiens	195-199
11981562-5	2002	Although natural hLF and rhLF underwent differential N-linked glycosylation, they were equally effective in three different in vivo infection models employing immunocompetent and leukocytopenic mice, and showed similar localization at sites of infection.	Nitrogen	53-54	HLF transcription factor, PAR bZIP family member	Homo sapiens	17-20
11854276-6	2002	The loops include those stabilized by six disulfide bonds or a loop C (Gly(69)-Glu(80)) and an N-glycosylated kallikrein loop (His(91)-Ile(103)) not containing a site linked by a disulfide bond.	Nitrogen	95-96	kallikrein 1-related peptidase b9	Mus musculus	110-120
11903056-2	2002	5T4 molecules are highly N-glycosylated transmembrane glycoproteins whose extracellular domain contains two regions of leucine-rich repeats (LRRs) and associated flanking regions, separated by an intervening hydrophilic sequence.	Nitrogen	25-26	trophoblast glycoprotein	Homo sapiens	0-3
16100110-0	2005	Alg14 recruits Alg13 to the cytoplasmic face of the endoplasmic reticulum to form a novel bipartite UDP-N-acetylglucosamine transferase required for the second step of N-linked glycosylation.	Nitrogen	104-105	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase catalytic subunit ALG13	Saccharomyces cerevisiae S288C	15-20
16209975-12	2005	In the group with ineffective IgG3 reduction, left ventricular ejection fraction increased after 3 months from 21.6 +/- 2% to 24.4 +/- 2% (NS), and from 24.3 +/- 2 to 34.7 +/- 4% in the group with improved IgG3 reduction (P &lt; .05).	Nitrogen	139-141	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	30-34
11923090-5	2002	In comparison with the LPL of other animals, the deduced amino acid sequence shows a high degree of similarity with a conservation of functional domains, e.g. catalytic triad, N-glycosylation sites, lipid and heparin binding regions.	Nitrogen	176-177	lipoprotein lipase	Homo sapiens	23-26
3418713-3	1988	Using N-methylacetamide as a model peptide, the free energies of the following processes were determined; (1) formation of the C=O ... H-N bond in water, (2) formation of the C=O ... N-N bond in CCl4, and (3) transfer of N-methylacetamide from water to CCl4.	Nitrogen	6-7	C-C motif chemokine ligand 4	Homo sapiens	253-257
15875186-2	2005	To obtain more insight in its cellular functioning, we investigated phosphorylation and N-linked glycosylation of BCRP.	Nitrogen	88-89	ATP binding cassette subfamily G member 2	Canis lupus familiaris	114-118
15875186-6	2005	We further mutated the asparagine residues 418, 557 and 596 in three putative N-linked glycosylation motifs of BCRP to alanines.	Nitrogen	78-79	ATP binding cassette subfamily G member 2	Canis lupus familiaris	111-115
3365686-7	1988	Nucleotide sequence analysis of the cloned complementary DNA indicated that the ME491 antigen consists of 237 amino acids (Mr 25,475) with four transmembrane regions and three putative N-glycosylation sites.	Nitrogen	0-1	CD63 molecule	Homo sapiens	80-85
16122234-2	2005	In addition, a reliable procedure for constructing a 10-monosubstituted bicyclo[5.3.0]deca-1,7-dien-9-one ring system by the rhodium(I)-catalyzed PKR of allenynes was developed under the condition of 10 atm of CO. Investigation of the rhodium(I)-catalyzed cycloisomerization of 4-phenylsulfonylnona-2,3-dien-8-ynes under nitrogen atmosphere gave the corresponding cyclohexene derivatives, whereas the C1-homologated allenynes produced cycloheptene derivatives and/or bicyclo[5.2.0]nonene skeletons depending on the substitution pattern at the allenic terminus.	Nitrogen	321-329	eukaryotic translation initiation factor 2 alpha kinase 2	Homo sapiens	146-149
11919156-6	2002	We regenerated the binding sites for AT-III on completely desulfated N-resulfated heparin and revealed the critical modification enzymes.	Nitrogen	69-70	serpin family C member 1	Homo sapiens	37-43
3421126-8	1988	After alkaline hydrolysis of lipid free myosin, 7 or 8 peaks of N-phosphoryl amino acids and phosphorylated amino acid derivates could be separated by ion exchange chromatography.	Nitrogen	64-65	myosin heavy chain 14	Homo sapiens	40-46
11773049-5	2002	The sorting mechanism of DPPIV implicates its association with detergent-insoluble membrane microdomains containing cholesterol and sphingolipids, whereas an efficient association largely depends on the presence of a fully complex N- and O-linked glycosylated DPPIV.	Nitrogen	231-232	dipeptidyl peptidase 4	Homo sapiens	25-30
11902834-2	2002	These lesions are targeted by the N-DNA glycosylase hOgg1, which catalyses excision of the aberrant base followed by cleavage of the phosphate backbone directly 5" to the resultant abasic site in a context, dependent manner.	Nitrogen	34-35	8-oxoguanine DNA glycosylase	Homo sapiens	52-57
16308274-1	2005	Neurosecretion is catalyzed by assembly of a soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE)-complex composed of SNAP-25, synaptobrevin and syntaxin.	Nitrogen	0-1	synaptosome associated protein 25	Homo sapiens	151-158
3265922-6	1988	Co-incubation of rIL-2-induced PBMC preparations with irradiated LA-N-1 and SK-N-BE2 cells, respectively, did not significantly enhance the cytolytic activity against other neuroblastoma targets and the standard Daudi cell line (p greater than or equal to 0.3).	Nitrogen	68-69	interleukin 2	Rattus norvegicus	17-22
16060651-3	2005	The CIT dianion represents a nitrogen-rich binary CN dianion, and 5 forms monoclinic crystals (a = 7.345(2) Angstroms, b = 9.505(2) Angstroms, c = 10.198(2) Angstroms, beta = 92.12(3) degrees, space group P2(1)/n, Z = 4).	Nitrogen	29-37	citron rho-interacting serine/threonine kinase	Homo sapiens	4-7
11863451-11	2002	Removal of chylomicron-sized n-6 TG emulsions is modulated by lipoprotein lipase (LPL), apoE, LDL-R, and lactoferrin-sensitive pathways.	Nitrogen	21-22	lactotransferrin	Mus musculus	105-116
3426805-1	1987	By the use of a newly developed procedure for the synthesis of tyrosine-O-sulfate peptides based on the direct incorporation of the suitably N alpha-protected tyrosine-O-sulfate residue along the synthetic route, the synthesis of two human gastrin-II analogues was successfully accomplished.	Nitrogen	141-142	gastrin	Homo sapiens	240-247
11908218-2	2002	BCl3-Ar chemistry was found to give satisfactory results; N2 and Cl2 were added to change the selectivity between GaAs and e-beam resist.	Nitrogen	58-60	BCL3 transcription coactivator	Homo sapiens	0-4
16076388-6	2005	Immunoprecipitation analyses show that LPP3 is a cell surface protein and undergoes N-glycosylation.	Nitrogen	84-85	phospholipid phosphatase 3	Homo sapiens	39-43
15993946-6	2005	In the systems with 3,3,3-tet, the MLL" type species are formed in which the oxygen atoms of the phosphate group and nitrogen atoms of the polyamine are involved in metallation, whereas the N3 atom from the pyrimidine ring of the nucleotide is located outside the inner coordination sphere of copper ion.	Nitrogen	117-125	lysine methyltransferase 2A	Homo sapiens	35-38
15950943-1	2005	The Prnd-encoded prion protein (PrP)-like protein, Doppel (Dpl), is a homologue of Prnp-encoded PrP, and is N-glycosylated protein with glycosylphosphatidylinositol anchor like PrP.	Nitrogen	108-109	prion like protein doppel	Mus musculus	51-57
2448022-1	1987	Intracellular recording from CA1 neurons confirmed that short periods of anoxia (95% N2 + 5% CO2 for 2-4 min) have a hyperpolarizing action, caused by a rise in K conductance.	Nitrogen	85-87	carbonic anhydrase 1	Rattus norvegicus	29-32
15950943-1	2005	The Prnd-encoded prion protein (PrP)-like protein, Doppel (Dpl), is a homologue of Prnp-encoded PrP, and is N-glycosylated protein with glycosylphosphatidylinositol anchor like PrP.	Nitrogen	108-109	prion like protein doppel	Mus musculus	59-62
16833861-1	2005	Scandium monoxide-dinitrogen complexes-OSc(N2), OScNN, and OScNN+-have been prepared by the reactions of laser-evaporated scandium monoxide with N2 or scandium atoms with N2O in solid argon.	Nitrogen	18-28	lanosterol synthase	Homo sapiens	39-45
16833861-2	2005	The ground-state scandium monoxide molecule reacted with N2 to form the side-bonded OSc(N2) complex spontaneously on annealing.	Nitrogen	57-59	lanosterol synthase	Homo sapiens	84-90
15788399-6	2005	The major sugar chains of ZPB were pauci and high mannose type chains that were similar in structure to the major neutral N-linked chain of the bovine zona.	Nitrogen	122-123	zona pellucida glycoprotein 4	Homo sapiens	26-29
15788399-9	2005	Moreover, Asn to Asp mutations at either of two of the N-glycosylation sites of ZPB, residue 203 or 220, significantly reduced the sperm binding activity of the ZPB/ZPC mixture, whereas a similar mutation at the third N-glycosylation site, Asn-333, had no effect on binding.	Nitrogen	55-56	zona pellucida glycoprotein 4	Homo sapiens	80-83
15788399-9	2005	Moreover, Asn to Asp mutations at either of two of the N-glycosylation sites of ZPB, residue 203 or 220, significantly reduced the sperm binding activity of the ZPB/ZPC mixture, whereas a similar mutation at the third N-glycosylation site, Asn-333, had no effect on binding.	Nitrogen	55-56	zona pellucida glycoprotein 4	Homo sapiens	161-164
15788399-9	2005	Moreover, Asn to Asp mutations at either of two of the N-glycosylation sites of ZPB, residue 203 or 220, significantly reduced the sperm binding activity of the ZPB/ZPC mixture, whereas a similar mutation at the third N-glycosylation site, Asn-333, had no effect on binding.	Nitrogen	218-219	zona pellucida glycoprotein 4	Homo sapiens	80-83
15604092-2	2005	The glycan structures of the porcine ZP and the complete N-glycosylation pattern of the ZPB/ZPC oligomer has been recently described.	Nitrogen	57-58	zona pellucida glycoprotein 4	Homo sapiens	88-91
12120370-1	2002	Rh(II)-catalyzed N-H insertion reaction of immobilized alpha-diazophosphonoacetate with 2-haloanilines followed by Horner-Emmons reaction gave immobilized enaminoesters, which were efficiently cyclized to indoles via intramolecular palladium catalyzed reaction on a polymer support.	Nitrogen	17-18	Rh blood group D antigen	Homo sapiens	0-5
11835564-5	2002	The substituent on the nitrogen (H or Me) was found to be always predominantly equatorial with respect to the heteroring, except for the epimeric 2-methyl derivatives with N-out conformations where steric constraints and the generalized anomeric effect resulted in the axial orientation of the C-2 methyl being favored.	Nitrogen	23-31	complement C2	Homo sapiens	294-297
11987413-1	2002	High concentrations of dissolved inorganic nitrogen and phosphate contributed much to the environmental problems in the Bohai Sea in the last decade.	Nitrogen	43-51	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	126-129
3624248-9	1987	alpha 2----3-Linked sialic acid and N-acetyllactosaminyl repeats are selectively present in the side chains attached to C-6 and C-2 of 2,6-substituted alpha-mannose and C-4 of 2,4-substituted alpha-mannose.	Nitrogen	36-37	complement C2	Homo sapiens	128-131
11824812-0	2002	Analysis of N-glycosylation of phospholipase A2 from venom of individual bees by microbore high-performance liquid chromatography-electrospray mass spectrometry using an ion trap mass spectrometer.	Nitrogen	12-13	phospholipase A2	Apis mellifera	31-47
15860012-5	2005	Members of the AtATG18 gene family are differentially expressed in response to different growth conditions, and one member of this family, AtATG18a, is induced both during sucrose and nitrogen starvation and during senescence.	Nitrogen	184-192	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	139-147
3624248-9	1987	alpha 2----3-Linked sialic acid and N-acetyllactosaminyl repeats are selectively present in the side chains attached to C-6 and C-2 of 2,6-substituted alpha-mannose and C-4 of 2,4-substituted alpha-mannose.	Nitrogen	36-37	complement C4A (Rodgers blood group)	Homo sapiens	169-172
15957369-9	2005	Time-course experiments indicated that N-acetylation of AF measured from intact mice leukemia cells were inhibited by berberine for up to 24 h. The NAT1 mRNA and NAT proteins in mouse leukemia cells were also inhibited by berberine.	Nitrogen	39-40	N-acetyl transferase 1	Mus musculus	148-152
11706042-0	2002	MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor.	Nitrogen	14-15	toll like receptor 4	Homo sapiens	9-13
15957369-9	2005	Time-course experiments indicated that N-acetylation of AF measured from intact mice leukemia cells were inhibited by berberine for up to 24 h. The NAT1 mRNA and NAT proteins in mouse leukemia cells were also inhibited by berberine.	Nitrogen	39-40	solute carrier family 38, member 3	Mus musculus	148-151
11706042-3	2002	We demonstrate that MD-2 contains 2 N-glycosylated sites at positions Asn(26) and Asn(114), whereas the amino-terminal ectodomain of human TLR4 contains 9 N-linked glycosylation sites.	Nitrogen	155-156	toll like receptor 4	Homo sapiens	139-143
3312952-4	1987	The RAD4 and RAD14 genes have a particular role in repair following exposure to those ethylating agents that preferentially alkylate oxygen, but not to those that preferentially ethylate nitrogen.	Nitrogen	187-195	DNA repair protein RAD14	Saccharomyces cerevisiae S288C	13-18
11706042-8	2002	Similar results were observed with TLR4 mutants lacking three or more N-linked glycosylation sites.	Nitrogen	70-71	toll like receptor 4	Homo sapiens	35-39
15814615-3	2005	It is shown that these theorems apply to several subcircuits of the full NCR circuit, most importantly to the URE2-GLN3 subcircuit that is independent of the other constituents but governs the switching behavior of the full NCR circuit under changes in nitrogen source.	Nitrogen	253-261	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	115-119
15806612-4	2005	This complex formation correlates with Gln3 being sequestered in the cytoplasm under conditions of excess nitrogen, where Gln3/Gat1-mediated transcription is minimal.	Nitrogen	106-114	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	39-43
15806612-3	2005	First, it regulates nitrogen catabolic gene expression by forming a complex with the GATA transcription factor Gln3.	Nitrogen	20-28	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	111-115
11756232-3	2002	In human hepatocytes, the major biotransformation pathway of PhIP was cytochrome P4501A2 (CYP1A2)-mediated N-oxidation to form the genotoxic metabolite 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (HONH-PhIP), which underwent glucuronidation at the N(2) and N3 positions of PhIP to form stable conjugates.	Nitrogen	107-108	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	70-88
2888040-3	1987	Rat hippocampal slices perfused for 40 min with buffer equilibrated with 95% nitrogen/5% carbon dioxide lost their extracellular CA1 population spikes and failed to recover after prolonged reoxygeneration.	Nitrogen	77-85	carbonic anhydrase 1	Rattus norvegicus	129-132
11756232-3	2002	In human hepatocytes, the major biotransformation pathway of PhIP was cytochrome P4501A2 (CYP1A2)-mediated N-oxidation to form the genotoxic metabolite 2-(hydroxyamino)-1-methyl-6-phenylimidazo[4,5-b]pyridine (HONH-PhIP), which underwent glucuronidation at the N(2) and N3 positions of PhIP to form stable conjugates.	Nitrogen	107-108	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	90-96
11856322-3	2002	A recombinant monomeric BChE lacking four out of nine N-glycosylation sites and the C-terminal oligomerization domain was stably expressed as a monomer in CHO cells.	Nitrogen	54-55	cholinesterase	Cricetulus griseus	24-28
15634943-6	2005	Moreover, inhibition of gamma-GT with acivicin increases the concentration of GSH and N-acetylcysteine conjugates of N-methyl-alpha-MeDA in brain dialysate, and there is a direct correlation between the concentrations of metabolites in dialysate and the extent of neurotoxicity, measured by decreases in serotonin (5-HT) and 5-hydroxyindole acetic (5-HIAA) levels.	Nitrogen	86-87	gamma-glutamyltransferase 1	Rattus norvegicus	24-32
15771436-5	2005	Among the compounds identified, the heterobivalent ligand 4m, containing an amide nitrogen and a sulfur atom at the 8-membered tether level, is one of the most potent and selective BuChE inhibitors described to date.	Nitrogen	82-90	butyrylcholinesterase	Homo sapiens	181-186
15735081-8	2005	Hepatic immunoreactive IGF-I was significantly correlated with serum IGF-I and nitrogen balance.	Nitrogen	79-87	insulin-like growth factor 1	Rattus norvegicus	23-28
15507441-4	2005	We established that the four potential N-glycosylation sites in Ost1p and the two potential N-glycosylation sites in Wbp1p were occupied in the mature proteins.	Nitrogen	39-40	dolichyl-diphosphooligosaccharide--protein glycotransferase subunit OST1	Saccharomyces cerevisiae S288C	64-69
15507441-4	2005	We established that the four potential N-glycosylation sites in Ost1p and the two potential N-glycosylation sites in Wbp1p were occupied in the mature proteins.	Nitrogen	39-40	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	117-122
15507441-4	2005	We established that the four potential N-glycosylation sites in Ost1p and the two potential N-glycosylation sites in Wbp1p were occupied in the mature proteins.	Nitrogen	92-93	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	117-122
11885896-13	2002	The ratio of total n-6:n-3 polyunsaturated fatty acids ranged from 39.2 for SP5 to 11.5 for SP1 (P &lt; 0.05).	Nitrogen	19-20	Sp5 transcription factor	Gallus gallus	76-79
11885896-13	2002	The ratio of total n-6:n-3 polyunsaturated fatty acids ranged from 39.2 for SP5 to 11.5 for SP1 (P &lt; 0.05).	Nitrogen	23-24	Sp5 transcription factor	Gallus gallus	76-79
12579892-1	2002	AIM: To study the effects of beta 2-adrenergic receptor-selective agonist clenbuterol on nitrogen metabolism and glucose-6-phosphate dehydrogenase activity of rat hepatocyte and its pharmacological mechanism.	Nitrogen	89-97	adrenoceptor beta 2	Rattus norvegicus	29-55
3295874-1	1987	Expression of the yeast arginase gene (CAR1) responds to both induction and nitrogen catabolite repression.	Nitrogen	76-84	arginase	Saccharomyces cerevisiae S288C	39-43
11718824-3	2001	The urea denaturation curves of N-dimethyl and acetyl derivatives of SBA are also similar to unmodified lectin but the midpoints, [D](1/2), are shifted to lower denaturant concentrations.	Nitrogen	32-33	lectin	Glycine max	69-72
15651808-3	2005	Loss of nitrogen occurs from the singlet excited state with X=H, t-Bu, and NMe2 and leads to the singlet aryl cation.	Nitrogen	8-16	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	75-79
3607034-1	1987	The mechanism-based inhibition of dopamine beta-hydroxylase (DBH; EC 1.14.17.1) by p-cresol (4-methylphenol) and other simple structural analogues of dopamine, which lack a basic side-chain nitrogen, is reported.	Nitrogen	190-198	dopamine beta-hydroxylase	Homo sapiens	34-59
15475412-8	2005	The K(m) value of AFQ N-glucuronidation in recombinant UGT1A4 microsomes was very close to that in human liver microsomes.	Nitrogen	22-23	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	55-61
15475412-9	2005	The formation of AFQ N-glucuronidation by human liver, jejunum, and recombinant UGT1A4 microsomes was effectively inhibited by trifluoperazine, a known specific substrate for UGT1A4.	Nitrogen	21-22	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	80-86
15475412-9	2005	The formation of AFQ N-glucuronidation by human liver, jejunum, and recombinant UGT1A4 microsomes was effectively inhibited by trifluoperazine, a known specific substrate for UGT1A4.	Nitrogen	21-22	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	175-181
15475412-12	2005	These results demonstrate that AFQ N-glucuronidation in human is mainly catalyzed by UGT1A4 in the liver and by UGT1A3, as well as UGT1A4 in the intestine.	Nitrogen	35-36	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	85-91
15475412-12	2005	These results demonstrate that AFQ N-glucuronidation in human is mainly catalyzed by UGT1A4 in the liver and by UGT1A3, as well as UGT1A4 in the intestine.	Nitrogen	35-36	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	131-137
3607034-1	1987	The mechanism-based inhibition of dopamine beta-hydroxylase (DBH; EC 1.14.17.1) by p-cresol (4-methylphenol) and other simple structural analogues of dopamine, which lack a basic side-chain nitrogen, is reported.	Nitrogen	190-198	dopamine beta-hydroxylase	Homo sapiens	61-64
3027378-13	1987	Since N-glycosidase F only reduces the size of gp110 to 105 kilodaltons, gp110 probably has both N- and O-linked glycosylation, gp110 is an abundant glycoprotein in Epstein-Barr virus-infected cells.	Nitrogen	6-7	ADRM1 26S proteasome ubiquitin receptor	Homo sapiens	47-52
15501908-5	2005	G6PDH activity increased in the roots supplied with nitrogen; no variations were observed in the leaves.	Nitrogen	52-60	g6pdh	Hordeum vulgare	0-5
15501908-7	2005	Western blots confirmed that P2-G6PDH protein was induced in the roots by nitrogen.	Nitrogen	74-82	g6pdh	Hordeum vulgare	32-37
15501908-8	2005	P1-G6PDH protein was absent in the roots and increased in the leaves by nitrogen supply to the plants.	Nitrogen	72-80	g6pdh	Hordeum vulgare	3-8
15501908-10	2005	The effects of light on Fd-GOGAT is discussed, together with the possibility for P2-G6PDH to sustain nitrogen assimilation upon illumination.	Nitrogen	101-109	g6pdh	Hordeum vulgare	84-89
3805010-12	1987	Finally, the capacity of Ns solubilized from treated membranes to stimulate adenylate cyclase activity when reconstituted into cyc- S49 lymphoma cell membranes was enhanced by approximately 50% compared to control.	Nitrogen	25-27	peptidylprolyl isomerase A, pseudogene 1	Mus musculus	86-89
16291246-3	2005	The NO-derived induction of HO-1 caused (a) rapid elimination of toxic heme to inhibit lipid peroxidation and to prevent further induction of iNOS, (b) rapid production of bile pigment antioxidants to scavenge reactive oxygen (O2-) and nitrogen (NO) metabolites, and (c) rapid production of carbon monoxide (CO) to inhibit further production of O2- and NO by blocking the activities of NADPH-oxidase and iNOS, respectively.	Nitrogen	236-244	heme oxygenase 1	Homo sapiens	28-32
3095314-3	1986	One of these cleavages occurs at C-1 of the 4-aminobutyl group during its transfer from the secondary amine nitrogen of spermidine to the nitrogen at the epsilon-position of a specific lysine residue in the polypeptide precursor of eukaryotic initiation factor 4D.	Nitrogen	108-116	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	33-36
15583810-0	2005	Altered N-glycosylation in CD45 and regulatory roles of altered N-glycosylation in galectin-1-induced growth inhibition in human diffuse large B cell lymphoma.	Nitrogen	64-65	galectin 1	Homo sapiens	83-93
15583810-13	2005	Alteration in N-glycosylation of CD45 may regulate lymphoma cell growth in DLBCL through the interaction between the N-glycans of CD45 and galectin-1.	Nitrogen	14-15	galectin 1	Homo sapiens	139-149
3095314-3	1986	One of these cleavages occurs at C-1 of the 4-aminobutyl group during its transfer from the secondary amine nitrogen of spermidine to the nitrogen at the epsilon-position of a specific lysine residue in the polypeptide precursor of eukaryotic initiation factor 4D.	Nitrogen	138-146	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	33-36
15575754-2	2004	In fact, the reaction of 7, easily prepared by reaction of 5"-O-Tosyl TSAO-T under basic nonnucleophilic conditions (potassium carbonate), with different classes of nucleophiles, for example, nitrogen-, oxygen-, sulfur-, and carbon-based nucleophiles, or with amino acids afforded, with total regio- and stereoselectivity, new bi-, tri-, and tetracyclic nucleosides.	Nitrogen	192-200	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	332-335
3818560-4	1986	This suggested that GPIV contains both N-linked and O-linked sugar chains.	Nitrogen	39-40	CD36 molecule	Homo sapiens	20-24
15566939-10	2004	A protein of 69 kDa was detected in the culture supernatant, and the size of the protein was reduced to 53 kDa by treatment with peptide-N-glycosidase F, which suggested that ST2LV is a new soluble secreted and N-glycosylated variant of the ST2 gene product.	Nitrogen	137-138	interleukin 1 receptor like 1	Gallus gallus	175-178
15252735-4	2004	Nitrogen-depletion experiments clearly showed that CND41 antisense tobacco maintained green leaves and constant protein levels, especially ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), throughout the whole plant, whereas wild-type tobacco showed marked senescence and the reduction of protein levels in the lower leaves.	Nitrogen	0-8	aspartyl protease family protein At5g10770-like	Nicotiana tabacum	51-56
15252735-6	2004	These results suggest that CND41 is involved in Rubisco degradation and the translocation of nitrogen during senescence.	Nitrogen	93-101	aspartyl protease family protein At5g10770-like	Nicotiana tabacum	27-32
2869484-7	1986	Five potential N-glycosylation sites are present in the gamma-glutamyl transpeptidase sequence.	Nitrogen	15-16	gamma-glutamyltransferase 1	Rattus norvegicus	56-85
15477162-1	2004	The molecular complexation reaction between iodine and the interesting mixed oxygen-nitrogen cyclic base N,N"-dibenzyl-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane (DBTODAOD) has been studied spectrophotometrically in CH2Cl2, CHCl3, and CCl4.	Nitrogen	84-92	C-C motif chemokine ligand 4	Homo sapiens	237-241
15542540-4	2004	By reverting one of the added N-glycosylation sites on the gp120 core, b12 binding was improved without affecting the epitope-masking properties of the original mutant.	Nitrogen	30-31	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	59-64
16664640-10	1986	A low level of NR activity was found in N-starved, etiolated plants and it was shown by western blotting to be an NR form with a different electrophoretic mobility in nondenaturing gels.	Nitrogen	15-16	nitrate reductase [NADH] 1	Zea mays	114-116
15247235-1	2004	The GATA transcription factors GLN3 and GAT1 activate nitrogen-regulated genes in Saccharomyces cerevisiae.	Nitrogen	54-62	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	31-35
15247235-3	2004	In the presence of a good nitrogen source, TOR (target of rapamycin) maintains GLN3 and NPR1 phosphorylated and inactive by inhibiting the type 2A-related phosphatase SIT4.	Nitrogen	26-34	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	79-83
15247235-3	2004	In the presence of a good nitrogen source, TOR (target of rapamycin) maintains GLN3 and NPR1 phosphorylated and inactive by inhibiting the type 2A-related phosphatase SIT4.	Nitrogen	26-34	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	167-171
15247235-5	2004	Specifically, loss of NPR1 causes nuclear translocation and activation of GLN3, but not GAT1, in nitrogen-rich conditions.	Nitrogen	97-105	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	74-78
15247235-7	2004	We also demonstrate that the E3/E4 ubiquitin-protein ligase proteins RSP5 and BUL1/2 are required for GLN3 activation under poor nitrogen conditions.	Nitrogen	129-137	NEDD4 family E3 ubiquitin-protein ligase	Saccharomyces cerevisiae S288C	69-73
4084493-13	1985	A new substrate activity for DBM was discovered, N-dealkylation of N-phenylethylenediamine and N-methyl-N-phenylethylenediamine, and the lack of O-dealkylation activity with phenyl 2-aminoethyl ether and 4-hydroxyphenyl 2-aminoethyl ether indicates that DBM N-dealkylation proceeds via initial one-electron abstraction from the benzylic nitrogen heteroatom.	Nitrogen	337-345	dopamine beta-hydroxylase	Homo sapiens	29-32
15247235-7	2004	We also demonstrate that the E3/E4 ubiquitin-protein ligase proteins RSP5 and BUL1/2 are required for GLN3 activation under poor nitrogen conditions.	Nitrogen	129-137	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	102-106
15252583-3	2004	Reaction between HL1 and labile Pt(II) and Pd(II) chlorides formed MCl2(HL1)2 complexes 4 (M = Pt) and 5 (M = Pd) in which a weak N-H...pi(aryl) hydrogen bonding interaction was identified in the solid-state structure of 4.	Nitrogen	130-131	intelectin 1	Homo sapiens	17-20
15252583-3	2004	Reaction between HL1 and labile Pt(II) and Pd(II) chlorides formed MCl2(HL1)2 complexes 4 (M = Pt) and 5 (M = Pd) in which a weak N-H...pi(aryl) hydrogen bonding interaction was identified in the solid-state structure of 4.	Nitrogen	130-131	intelectin 1	Homo sapiens	72-75
4075234-0	1985	Ca2+-specific fluorescence changes in N-dansylaminoethyl-labelled oncomodulin.	Nitrogen	38-39	oncomodulin	Rattus norvegicus	66-77
15225646-2	2004	Here, we show that the mouse GFRalpha4 is a functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET, but has an almost undetectable capacity to recruit RET into the 0.1% Triton X-100 insoluble membrane fraction.	Nitrogen	56-57	persephin	Mus musculus	140-149
3924455-6	1985	Preliminary biochemical characterization of M7/20 immunoprecipitates of detergent extracts from both surface-iodinated and internally D-[3H]glucosamine-labeled T lymphoblasts indicated that the murine IL-2 receptor is an N-glycosylated 58,000-Da glycoprotein.	Nitrogen	221-222	interleukin 2	Mus musculus	201-205
15225646-2	2004	Here, we show that the mouse GFRalpha4 is a functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET, but has an almost undetectable capacity to recruit RET into the 0.1% Triton X-100 insoluble membrane fraction.	Nitrogen	56-57	persephin	Mus musculus	151-155
15296462-2	2004	We have compared the N-linked glycosylation profile of A33 antigen naturally expressed in a human colorectal cancer cell line with recombinant human A33 antigen (rA33) produced in insect cell culture using the baculovirus expression vector.	Nitrogen	21-22	glycoprotein A33	Homo sapiens	55-58
14970238-0	2004	Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae.	Nitrogen	79-87	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	59-63
14970238-4	2004	Gln3 re-accumulates in the cytoplasm when cells are returned to a good nitrogen source.	Nitrogen	71-79	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
3868345-5	1985	AT III 25 U/kg and in combination with heparin showed marginal effects, 50 U/kg AT III resulted in increased survival rate and time, improvement of pathological changes of coagulation parameters and of blood urea nitrogen and serum creatinine levels.	Nitrogen	213-221	serpin family C member 1	Homo sapiens	80-86
14970238-10	2004	These data indicate the actin cytoskeleton is required for nuclear localization of Gln3 in response to limiting nitrogen but not rapamycin-treatment.	Nitrogen	112-120	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	83-87
14970238-11	2004	Therefore, the actin cytoskeleton either participates in the response of Gln3 intracellular localization to nitrogen limitation before Tor1/2, or Tor1/2 inhibition only mimics the outcome of nitrogen limitation rather than directly regulating it.	Nitrogen	108-116	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	73-77
6501522-3	1984	The first approach led to an N-methyl derivative of lofemizole which could be successfully analysed by gas--chromatography employing a flame-ionization detector, reaching a sensitivity of 2 micrograms/ml.	Nitrogen	29-30	gastrin	Homo sapiens	103-106
15023143-3	2004	A 1020-basepair ICAM-2 cDNA generated from pig lung RNA contained an open reading frame (ORF) encoding a 277-amino-acid protein with six potential N-linked glycosylation sites.	Nitrogen	25-26	intercellular adhesion molecule 2	Sus scrofa	16-22
15027853-2	2004	Introduction of nitrogen-containing heteroaromatic groups at the 4-position of the quinoline moiety of our non-peptide B(2) receptor antagonists resulted in enhancing binding affinities for the human B(2) receptor and reducing binding affinities for the guinea pig one, providing new structural insights into species difference.	Nitrogen	16-24	bradykinin receptor B2	Homo sapiens	119-132
15027853-2	2004	Introduction of nitrogen-containing heteroaromatic groups at the 4-position of the quinoline moiety of our non-peptide B(2) receptor antagonists resulted in enhancing binding affinities for the human B(2) receptor and reducing binding affinities for the guinea pig one, providing new structural insights into species difference.	Nitrogen	16-24	bradykinin receptor B2	Homo sapiens	200-213
14688283-4	2004	Here we investigated the role of N-glycosylation of Kv1.1 and Kv1.4 on their protein stability, cellular localization pattern, and trafficking to the cell surface.	Nitrogen	33-34	potassium voltage-gated channel subfamily A member 1	Homo sapiens	52-57
6501522-4	1984	The second approach led to the N-(2-chlorobenzoyl) derivative of lofemizole which was suitable for pharmacokinetic investigation using gas--liquid chromatography with electron-capture detection, and reaching a much higher sensitivity of 10 ng/ml of plasma.	Nitrogen	31-32	gastrin	Homo sapiens	135-138
14688283-5	2004	We found that preventing N-glycosylation of Kv1.4 decreased its protein stability, induced its high partial intracellular retention, and decreased its cell surface protein levels, whereas it had little or no effect on these parameters for Kv1.1.	Nitrogen	25-26	potassium voltage-gated channel subfamily A member 4	Homo sapiens	44-49
11914029-10	2001	However, it has been found that IGFBP-1 and fIGF-I levels were correlated with the levels of the weekly nitrogen balance of each patient in group II at the end of the trial.	Nitrogen	104-112	insulin like growth factor binding protein 1	Homo sapiens	32-39
6431000-5	1984	The addition of GEF to T cell hybridoma 23A4 cell switches the cells from the formation of unglycosylated IgE binding factor to the formation of N-glycosylated IgE binding factor.	Nitrogen	145-146	rho/rac guanine nucleotide exchange factor (GEF) 2	Mus musculus	16-19
11789872-3	2001	Both bidentate and unsaturated monodenate heteronuclear nitrogen bases form hexa-coordinated adducts with 1:1 stoichiomety (metal chelate, base).	Nitrogen	56-64	hexosaminidase subunit alpha	Homo sapiens	76-80
14583611-6	2004	In addition, Hsp90 suppression in NN plants compromises N-mediated resistance to tobacco mosaic virus.	Nitrogen	34-35	heat shock protein 90 alpha family class A member 1	Homo sapiens	13-18
6432920-11	1984	These results suggest that maturation of tyrosinase may occur via T1" and T1"" as precursors of T3, or possibly T1 through the addition of N-glycosydically linked oligosaccharide moieties which can be interrupted by glucosamine and tunicamycin.	Nitrogen	139-140	tyrosinase	Mus musculus	41-51
14744631-2	2004	In serum-deprived human fibroblasts, exposure to 100 microM N-fMLP or 10 microM peptide W for 1 min induced both p47phox translocation and NADPH-dependent superoxide generation.	Nitrogen	60-61	pleckstrin	Homo sapiens	113-116
14697754-8	2004	Three DNA N-glycosylases/AP lyases, Ntg1, Ntg2 and Ogg1, can also incise AP sites in DNA.	Nitrogen	7-8	8-oxoguanine glycosylase OGG1	Saccharomyces cerevisiae S288C	51-55
11504859-7	2001	Further mutational analysis of the Naja/mouse nAChR demonstrated that an N-glycosylation signal in the ligand binding domain that is unique to N. haje is responsible for alpha-BTX resistance.	Nitrogen	35-36	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	46-51
11504269-5	2001	Thus, the present in vitro study on clozapine N-demethylation suggests that CYP1A2 is the most important form at low concentrations, which is in agreement with clinical findings.	Nitrogen	46-47	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	76-82
24458697-3	1984	The total protection of the enzyme against N-ethylmaleimide inactivation afforded by the substrate, phosphoenolpyruvate, was correlated with the protection of one mol ((3)H)N-ethylmaleimide reactive residue per mol subunit.The complete inactivation of phosphoenolpyruvate carboxylase by N-ethylmaleimide and the protection afforded by phosphoenolpyruvate against modification suggest the presence of an essential cysteine residue in the catalytic site of the C4 leaf enzyme.	Nitrogen	43-44	MLO-like protein 4	Zea mays	252-283
11459490-3	2001	This viscosity effect is consistent with a stepwise denitrogenation mechanism in the liquid-phase photolysis of DBH, which proceeds through an unsymmetrical, nitrogen-containing transient, namely the singlet diazenyl diradical.	Nitrogen	54-62	dopamine beta-hydroxylase	Homo sapiens	112-115
14761847-9	2004	Interestingly, oxidized base-specific DNA N-glycosylases, Fpg, Nth, Ntg1, Ntg2, Ogg1, hNth1 and hOgg1, cannot repair Ca in DNA.	Nitrogen	39-40	8-oxoguanine DNA glycosylase	Homo sapiens	80-84
14761847-9	2004	Interestingly, oxidized base-specific DNA N-glycosylases, Fpg, Nth, Ntg1, Ntg2, Ogg1, hNth1 and hOgg1, cannot repair Ca in DNA.	Nitrogen	39-40	8-oxoguanine DNA glycosylase	Homo sapiens	96-101
16663684-0	1984	Partitioning of Nitrogen among Ribulose-1,5-bisphosphate Carboxylase/Oxygenase, Phosphoenolpyruvate Carboxylase, and Pyruvate Orthophosphate Dikinase as Related to Biomass Productivity in Maize Seedlings.	Nitrogen	16-24	MLO-like protein 4	Zea mays	80-111
14512741-0	2003	1H, 15N, and 13C chemical shift assignments of the Escherichia coli nitrogen regulatory phosphocarrier IIA(Ntr).	Nitrogen	68-76	colicin Ia immunity protein	Escherichia coli	103-106
11328816-7	2001	In the ceramidase overexpressing HEK293 cells, 133-kDa (Golgi-form) and 113-kDa (endoplasmic reticulum-form) Myc-tagged ceramidases were detected, whereas these two proteins were converted to a 87-kDa protein concomitantly with loss of activity when expressed in the presence of tunicamycin, indicating that the N-glycosylation process is indispensable for the expression of the enzyme activity.	Nitrogen	312-313	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	109-112
6326397-3	1984	From both values a factor was calculated, which permits the estimation of fecal bacterial nitrogen from fecal DAP content.	Nitrogen	90-98	death-associated protein	Rattus norvegicus	110-113
11459203-4	2001	This hypothesis was tested with respect to CYP1A2, by using the clearance of caffeine by N-demethylation as a phenotypic trait measurement of the isoform"s catalytic activity.	Nitrogen	89-90	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	43-49
14565980-3	2003	Because conserved cell cycle regulators, the mitotic cyclin-dependent kinase Clb2/Cdc28, and its inhibitor Swe1 were found to be involved in both nitrogen starvation- and short chain alcohol-induced filamentous differentiation, they were identified as components of the core mechanism for filamentous differentiation.	Nitrogen	146-154	cyclin-dependent serine/threonine-protein kinase CDC28	Saccharomyces cerevisiae S288C	82-87
6326397-8	1984	It is concluded that the factor used to calculate fecal microbial nitrogen from fecal DAP content is dependent on the kind of dietary fiber ingested.	Nitrogen	66-74	death-associated protein	Rattus norvegicus	86-89
14582987-4	2003	These experiments demonstrated 5-chlorogenic acid to be the most powerful antioxidant in vitro, whereas, in contrast, chemopreventive effects on the GST activity were found for the N-methylpyridinium ion, the structure of which was elucidated by LC-MS and NMR experiments and confirmed by synthesis.	Nitrogen	181-182	glutathione S-transferase kappa 1	Homo sapiens	149-152
6703860-11	1984	Nuclei of N-nitrosomethylurea-induced mammary tumors of the rat possess apparently a "factor" which is able to inactivate the cytoplasmic estradiol receptor and is highly active at elevated temperatures.	Nitrogen	0-1	estrogen receptor 1	Rattus norvegicus	138-156
14581570-11	2003	Envs from two patients contained 28 to 32 N-glycosylation sites in gp120, compared to around 25 in lab strains and well-characterized primary isolates.	Nitrogen	42-43	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	67-72
14535784-0	2003	Novel synthesis of carbapenam by intramolecular attack of lactam nitrogen toward eta1-allenyl and eta3-propargylpalladium complex.	Nitrogen	65-73	secreted phosphoprotein 1	Homo sapiens	81-85
12860997-18	2003	Our data suggest that Sss1p coordinates translocation across the ER membrane and N-linked glycosylation of secretory proteins.	Nitrogen	81-82	SEC61 translocon subunit gamma	Homo sapiens	22-27
11344270-7	2001	Second, with a reticulocyte-lysate supplemented with dog-pancreas microsomes, we demonstrated that N-glycosylation occurs at position 429 of AtHKT1.	Nitrogen	99-100	high-affinity K+ transporter 1	Arabidopsis thaliana	141-147
11331002-2	2001	In mammalian cells, RAMP1 is required for mature N-glycosylation of the hCRLR predicted to occur at Asn(60), Asn(112), and/or Asn(117) in the amino-terminal extracellular domain.	Nitrogen	49-50	receptor activity modifying protein 1	Homo sapiens	20-25
11331002-5	2001	In contrast, the hCRLR Asn(60,112) to Thr double mutant exhibited defective RAMP1-dependent N-glycosylation, and impaired cell surface expression and CGRP receptor function.	Nitrogen	92-93	receptor activity modifying protein 1	Homo sapiens	76-81
11349921-4	2001	Exclusively terminal, N-bound transoid thiocyanate bonding is observed with eta1-Odpp (4), eta5/-C5H4Me (6) and eta2-Ph2Pz (7) ligands attached approximately perpendicular to the N...N vector.	Nitrogen	22-23	secreted phosphoprotein 1	Homo sapiens	76-85
11259345-4	2001	Metabolic activation of the heterocyclic amines predominantly involves CYP1-mediated N-hydroxylation and then O-esterification by phase II enzymes.	Nitrogen	85-86	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	71-75
6087242-2	1984	Energy yields for the synthesis of HCN and H2CO from a spark discharge were determined for various mixtures of CH4, CO, CO2, H2, H2O, N2 and NH3.	Nitrogen	134-136	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	35-38
11472075-5	2001	At each level of food intake, rats infused with LR(3)IGF-I maintained higher body weight (around 3-8%;P&lt; 0.001) and nitrogen retention (P&lt; 0.001) than those infused with vehicle alone but muscle protein was not conserved.	Nitrogen	119-127	insulin-like growth factor 1	Rattus norvegicus	53-58
14672363-3	2003	Both the cultures (C1 and C2) were able to utilize acrylonitrile up to a concentration of 2000 mg/l as the sole source of carbon and nitrogen.	Nitrogen	133-141	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	19-28
12941910-5	2003	The variant viruses included three derivatives of SIVmac239 with substitutions in specific N-linked glycosylation sites of gp120 and a fourth variant that lacked the 100 amino acids that encompass the V1 and V2 loops.	Nitrogen	91-92	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	123-128
6225713-8	1983	PSP t/2 in rats treated with gentamicin or puromycin amino-nucleoside as well as that in rats given HgCl2 was increased in correlation with changes in common renal functional parameters such as serum urea nitrogen, serum creatinine, urinary protein and morphologic changes of the kidney.	Nitrogen	205-213	persephin	Rattus norvegicus	0-3
14531463-1	2003	Concentration dependency of stereoselective N-depropylation metabolism of propafenone was studied by using transgenic cell line expressing human CYP1A2.	Nitrogen	44-45	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	145-151
14531463-3	2003	The experimental results showed that CYP1A2 was involved in enantioselective N-depropylation of propafenone and that the metabolic stereoselectivity depends on substrate concentration.	Nitrogen	77-78	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	37-43
11281716-4	2001	In contrast, fusion of SCF to Cel5ACBM2a, which lacks potential N-linked glycosylation sites, resulted in the production of polypeptides which bound tightly to cellulose.	Nitrogen	64-65	kit ligand	Mus musculus	23-26
11261970-7	2001	The reaction between 2 equiv of L1 and [PdCl(eta3-C3H5)]2 affords the [PdCl(eta3-C3H5)(Ph2PCH2CH(Ph)NHPh-kappaP)] complex in which an unexpected N-H.Cl intramolecular interaction has been observed by an X-ray diffraction analysis.	Nitrogen	100-101	phosducin like	Homo sapiens	40-44
11261970-7	2001	The reaction between 2 equiv of L1 and [PdCl(eta3-C3H5)]2 affords the [PdCl(eta3-C3H5)(Ph2PCH2CH(Ph)NHPh-kappaP)] complex in which an unexpected N-H.Cl intramolecular interaction has been observed by an X-ray diffraction analysis.	Nitrogen	100-101	phosducin like	Homo sapiens	71-75
11261970-10	2001	Variable-temperature 31P[1H] NMR studies on the allyl complexes show that the eta3/eta1 allyl interconversion is enhanced by a positive charge and also by a N-H.Cl intramolecular interaction.	Nitrogen	29-30	secreted phosphoprotein 1	Homo sapiens	83-87
11096087-1	2001	Gln3p is a nitrogen catabolite repression-sensitive GATA-type transcription factor.	Nitrogen	11-19	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-5
11096087-4	2001	When cells are starved from nitrogen nutrients or treated with rapamycin, however, Gln3p becomes translocated into the nucleus, thereby activating the expression of genes involved in nitrogen utilization and transport.	Nitrogen	28-36	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	83-88
11096087-4	2001	When cells are starved from nitrogen nutrients or treated with rapamycin, however, Gln3p becomes translocated into the nucleus, thereby activating the expression of genes involved in nitrogen utilization and transport.	Nitrogen	183-191	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	83-88
14756320-10	2003	On the other hand, an interesting relationship, in structure and function, was found between LjMYB101 and LjGln1, suggesting an alternative role for MYB101 in regulation of nitrogen metabolism.	Nitrogen	173-181	Glutamine synthetase cytosolic isozyme	Lotus japonicus	106-112
6825202-2	1983	Two structurally similar nitrogen heterocycles, 6-ethoxy-2-methylbenzoxazole and 6-methoxy-2-methylbenzothiazole, were moderately potent inhibitors of PB/AHH and APDM.	Nitrogen	25-33	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	154-157
12951035-2	2003	ADP is an integral membrane N-linked, O-linked palmitoylated glycoprotein of 101 amino acids (aa) that localizes to the nuclear membrane, endoplasmic reticulum (ER), and Golgi.	Nitrogen	28-29	WD and tetratricopeptide repeats 1	Homo sapiens	0-3
11222615-6	2001	An isogenic snr-1::Gm insertional mutant was unable to grow aerobically with nitrate as a sole nitrogen source or anaerobically with nitrate as an electron acceptor.	Nitrogen	95-103	cytochrome C Snr1	Pseudomonas aeruginosa PAO1	12-17
14582193-6	1982	Two other mutants previously shown to be resistant to nitrogen repression contained large quantities of CAR1 RNA regardless of the nitrogen source in the medium.	Nitrogen	54-62	arginase	Saccharomyces cerevisiae S288C	104-108
11238772-2	2001	It is postulated that the branched-chain aminotransferase (BCAT) isoenzymes (mitochondrial BCATm and cytosolic BCATc) are localized in different cell types and operate in series to provide nitrogen for optimal rates of de novo glutamate synthesis.	Nitrogen	189-197	branched chain amino acid transaminase 1	Homo sapiens	111-116
12867488-0	2003	Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes.	Nitrogen	36-37	indoleamine 2,3-dioxygenase 2	Rattus norvegicus	56-63
12867488-2	2003	3-(Indol-1-yl)-1,2-benzisoxazole was reduced to the corresponding amidine (resulting from N-O bond cleavage) under anaerobic conditions.	Nitrogen	90-91	indoleamine 2,3-dioxygenase 2	Rattus norvegicus	3-10
12719423-7	2003	If N-glycosylation inhibitors prevent the association with calnexin, the TRP-2 nascent chain undergoes an accelerated degradation process.	Nitrogen	3-4	calnexin	Mus musculus	59-67
11160238-5	2001	Actual levels of reactive oxygen and nitrogen intermediates in the livers of infected IL-4(-/-) animals are thus likely to be considerably higher than those in the livers of infected WT mice.	Nitrogen	37-45	interleukin 4	Mus musculus	86-90
11160238-8	2001	Taken together, these data indicate that IL-4 is playing a protective role during schistosomiasis by controlling the tight regulation of the generation of reactive oxygen and nitrogen intermediates in the liver.	Nitrogen	175-183	interleukin 4	Mus musculus	41-45
11082192-0	2000	Regulation of pyc1 encoding pyruvate carboxylase isozyme I by nitrogen sources in Saccharomyces cerevisiae.	Nitrogen	62-70	pyruvate carboxylase 1	Saccharomyces cerevisiae S288C	14-18
7050082-9	1982	From these observations, we conclude that dal81 mutant strains possess a defect in the induction of enzyme synthesis; enzyme production due to relief of nitrogen catabolite repression, however, appears normal.	Nitrogen	153-161	Dal81p	Saccharomyces cerevisiae S288C	42-47
11159917-4	2000	Gel filtration analysis of the pronase-resistant gC-1 O-glycan clusters from a glycoprotein mutant, lacking a site for N-linked glycosylation at Asn 73 in the vicinity of the O-glycosylation signal, suggested that one function of this N-linked glycan was to modulate the access for GalNAc transferases to one particular O-glycosylation peptide signal (aa 80-104).	Nitrogen	119-120	solute carrier family 25 member 22	Homo sapiens	49-53
12829373-0	2003	N-glycosylation patterns of HSA/CD24 from different cell lines and brain homogenates: a comparison.	Nitrogen	0-1	CD24a antigen	Mus musculus	32-36
7162801-2	1982	From their results, it appears that a variety of organic compounds, including unsaturated hydrocarbons and nitriles such as HCN, can be synthesized into noticeable amounts from CH4-N2 mixtures.	Nitrogen	181-183	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	124-127
12786955-2	2003	The cDNA sequence predicts that rat DSP has 13 potential casein kinase phosphorylation sites and six potential N-linked glycosylation sites.	Nitrogen	6-7	dentin sialophosphoprotein	Rattus norvegicus	36-39
12786955-4	2003	Our findings in the present study show that rat DSP has 6.2 phosphates per molecule and that the majority of carbohydrates are attached to the protein through N-linked glycosylations.	Nitrogen	159-160	dentin sialophosphoprotein	Rattus norvegicus	48-51
11163076-6	2000	Thus, the deletion of the N-linked glycosylation signal in HLA-Cw4 and -Cw6 greatly reduced recognition by KIR2DL1.	Nitrogen	26-27	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1	Homo sapiens	107-114
7042758-11	1982	At a bacteria/leukocyte ratio of 10:1, killing of gram-positive, BPI-resistant, Staphylococcus epidermidis is markedly impaired in the absence of oxygen (76.4 +/- 3.3% killing in room air, 29.2 +/- 8.2% killing in nitrogen).	Nitrogen	214-222	bactericidal permeability increasing protein	Homo sapiens	65-68
11148290-5	2000	Cnx1 is constitutively expressed in all organs and in plants grown on different nitrogen sources.	Nitrogen	80-88	calnexin 1	Arabidopsis thaliana	0-4
12624103-4	2003	Upon reintroduction of preferred nitrogen, Gln3p is exported from the nucleus by Crm1p/Xpo1p.	Nitrogen	33-41	exportin 1	Homo sapiens	81-86
12624103-4	2003	Upon reintroduction of preferred nitrogen, Gln3p is exported from the nucleus by Crm1p/Xpo1p.	Nitrogen	33-41	exportin 1	Homo sapiens	87-92
7061465-9	1982	However, when artificial ligands which coordinate through nitrogen or sulfur were added to either P-450LM2 or P-450LM4, the induced spectra did not resemble the native spectrum and, in fact, were distinctive and characteristic of the particular ligand type.	Nitrogen	58-66	cytochrome P450 2B4	Oryctolagus cuniculus	98-106
12711319-3	2003	The recombinant N was phosphorylated by BHK cellular extracts and by purified CK-II.	Nitrogen	16-17	casein kinase 2 alpha 1	Homo sapiens	78-83
12711319-4	2003	In addition, the phosphorylation of the recombinant N in vitro can be blocked by a CK-II inhibitor, heparin.	Nitrogen	52-53	casein kinase 2 alpha 1	Homo sapiens	83-88
12711319-5	2003	Furthermore, N phosphorylation in the virus-infected cells can be inhibited by a CK-II specific inhibitor, 5,6-dichloro-beta-D-ribofuranosyl benzimidazole.	Nitrogen	13-14	casein kinase 2 alpha 1	Homo sapiens	81-86
12910288-6	2003	Our results suggest that (GCC)n-binding proteins differing from CGGBP-20 regulate activity of the VLDL receptor gene via cis-element (GCC)8.	Nitrogen	30-31	very low density lipoprotein receptor	Homo sapiens	98-111
10940301-1	2000	Gln3p is a GATA-type transcription factor responsive to different nitrogen nutrients and starvation in yeast Saccharomyces cerevisiae.	Nitrogen	66-74	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-5
10940301-3	2000	Rapamycin causes dephosphorylation and nuclear translocation of Gln3p, thereby activating nitrogen catabolite repressible-sensitive genes.	Nitrogen	90-98	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	64-69
7061465-9	1982	However, when artificial ligands which coordinate through nitrogen or sulfur were added to either P-450LM2 or P-450LM4, the induced spectra did not resemble the native spectrum and, in fact, were distinctive and characteristic of the particular ligand type.	Nitrogen	58-66	cytochrome P450 1A2	Oryctolagus cuniculus	110-118
11067927-5	2000	In this paper we show that QPP, like CD26/DPPIV, is synthesized with a propeptide and undergoes N:-glycosylation.	Nitrogen	96-97	dipeptidyl peptidase 7	Homo sapiens	27-30
11067927-5	2000	In this paper we show that QPP, like CD26/DPPIV, is synthesized with a propeptide and undergoes N:-glycosylation.	Nitrogen	96-97	dipeptidyl peptidase 4	Homo sapiens	37-41
7061465-12	1982	These results provide strong evidence that the native sixth ligand in P-450LM2 is oxygen rather than nitrogen.	Nitrogen	101-109	cytochrome P450 2B4	Oryctolagus cuniculus	70-78
11067927-5	2000	In this paper we show that QPP, like CD26/DPPIV, is synthesized with a propeptide and undergoes N:-glycosylation.	Nitrogen	96-97	dipeptidyl peptidase 4	Homo sapiens	42-47
6266299-0	1981	Angiotensin converting enzyme concentrations in the lung lavage of normal rabbits and rabbits treated with nitrogen mustard exposed to hyperoxia.	Nitrogen	107-115	angiotensin-converting enzyme	Oryctolagus cuniculus	0-29
12775055-4	2003	Most of the remaining C and N content of RDX, MNX, and HMX was found in HCHO, N2O, HCOOH, and NH3.	Nitrogen	28-29	keratin 86	Homo sapiens	46-49
11076970-1	2000	Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors.	Nitrogen	36-44	Rtg3p	Saccharomyces cerevisiae S288C	85-89
7305948-12	1981	The absorption coefficient and nitrogen content of C1q were also determined.	Nitrogen	31-39	complement component 1, q subcomponent, alpha polypeptide	Mus musculus	51-54
11058089-8	2000	Like proteinase B-deficient cells, aut4-deleted cells show a partial reduction in total protein breakdown during nitrogen starvation.	Nitrogen	113-121	Atg22p	Saccharomyces cerevisiae S288C	35-39
12654890-1	2003	Glutamine synthetase (GSase) is a key enzyme in nitrogen metabolism and encoded by a single gene in mammals.	Nitrogen	48-56	glutamine synthetase	Oncorhynchus mykiss	0-20
12654890-1	2003	Glutamine synthetase (GSase) is a key enzyme in nitrogen metabolism and encoded by a single gene in mammals.	Nitrogen	48-56	glutamine synthetase	Oncorhynchus mykiss	22-27
6258821-2	1981	While switching from a helium-oxygen to a nitrogen-oxygen mixture of same P1O2 and total pressure, the sum of the arterial inert gas partial pressure was transiently less than the one in the inspired gases: there was an arterial under-saturation: PaHe + PaN2 = 0.68 (P1He + P1N2).	Nitrogen	42-50	poly(A) specific ribonuclease subunit PAN2	Homo sapiens	254-258
12732683-9	2003	RESULTS: The [(99m)Tc(N)(PNP)(L)](+) complexes are monocationic and possess a distorted square-pyramidal geometry in which the TcN multiple bond occupies an apical position and the diphosphine and dithiocarbamate ligands span the residual 4 coordination positions on the basal plane through the 2 phosphorus atoms and the 2 sulfur atoms, respectively.	Nitrogen	22-23	purine nucleoside phosphorylase	Rattus norvegicus	25-28
12642466-6	2003	Almotriptan is also metabolized at the dimethylaminoethyl group by N-demethylation, a reaction that is carried out by five different cytochrome P450s, flavin monooxygenase-3 mediated N-oxidation, and MAO-A catalyzed oxidative deamination to form the indole acetic acid and the indole ethyl alcohol derivatives of almotriptan.	Nitrogen	67-68	monoamine oxidase A	Homo sapiens	200-205
12692337-2	2003	Infiltration of tobacco leaves with submicromolar to micromolar concentrations of N-myristoylethanolamine (NAE 14:0) resulted in an increase in relative phenylalanine ammonia-lyase (PAL) transcript abundance within 8 h after infiltration, and this PAL activation was reduced after co-infiltration with cannabinoid receptor antagonists (AM 281 and SR 144528).	Nitrogen	82-83	phenylalanine ammonia-lyase	Nicotiana tabacum	153-180
12692337-2	2003	Infiltration of tobacco leaves with submicromolar to micromolar concentrations of N-myristoylethanolamine (NAE 14:0) resulted in an increase in relative phenylalanine ammonia-lyase (PAL) transcript abundance within 8 h after infiltration, and this PAL activation was reduced after co-infiltration with cannabinoid receptor antagonists (AM 281 and SR 144528).	Nitrogen	82-83	phenylalanine ammonia-lyase	Nicotiana tabacum	182-185
12692337-2	2003	Infiltration of tobacco leaves with submicromolar to micromolar concentrations of N-myristoylethanolamine (NAE 14:0) resulted in an increase in relative phenylalanine ammonia-lyase (PAL) transcript abundance within 8 h after infiltration, and this PAL activation was reduced after co-infiltration with cannabinoid receptor antagonists (AM 281 and SR 144528).	Nitrogen	82-83	phenylalanine ammonia-lyase	Nicotiana tabacum	248-251
11044255-12	2000	In summary, these studies show a striking induction by dietary n-6 PUFAs of hepatic IGFBP-1, a protein that has been implicated in liver cancer development.	Nitrogen	1-2	insulin-like growth factor binding protein 1	Rattus norvegicus	84-91
11052789-6	2000	X-ray crystal structure of the ternary complex of 3a, DHFR, and NADPH showed that the pyrrolo[2, 3-d]pyrimidine ring binds in a "2,4-diamino mode" in which the pyrrole nitrogen mimics the 4-amino moiety of 2,4-diaminopyrimidines.	Nitrogen	168-176	dihydrofolate reductase	Homo sapiens	54-58
11177255-3	2000	It is suggested that N-activation of methyl-D-aspartate receptors by high concentrations of nooglutil and mexidol reduced CA1 pyramidal cell responsiveness.	Nitrogen	21-22	carbonic anhydrase 1	Rattus norvegicus	122-125
10988254-0	2000	The C-terminal N-glycosylation sites of the human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, adn -VI) are necessary for the expression of full enzyme activity.	Nitrogen	15-16	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	98-106
10988254-2	2000	Human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, and -VI) contain two conserved C-terminal N-glycosylation sites (hFucTIII: Asn154 and Asn185; hFucTV: Asn167 and Asn198; and hFucTVI: Asn153 and Asn184).	Nitrogen	110-111	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	54-62
12617623-8	2003	In CH3CN under N2, a rapid reaction occurs between trans-[OsIV=N-CN] and PPh3 (kPPh3(DMF, 25.0 +/- 0.1 degrees C) = 4.06 +/- 0.02 M-1 s-1) to form the nitrilic N-bound Os(II)-(N-cyano)iminophosphorano product, trans-[OsII(tpy)(Cl)2(NalphaCNbetaPPh3)] (trans-[OsII-NalphaC-Nbeta=PPh3]).	Nitrogen	15-17	protein phosphatase 4 catalytic subunit	Homo sapiens	73-77
12617623-8	2003	In CH3CN under N2, a rapid reaction occurs between trans-[OsIV=N-CN] and PPh3 (kPPh3(DMF, 25.0 +/- 0.1 degrees C) = 4.06 +/- 0.02 M-1 s-1) to form the nitrilic N-bound Os(II)-(N-cyano)iminophosphorano product, trans-[OsII(tpy)(Cl)2(NalphaCNbetaPPh3)] (trans-[OsII-NalphaC-Nbeta=PPh3]).	Nitrogen	15-17	protein phosphatase 4 catalytic subunit	Homo sapiens	80-84
6258821-3	1981	During the opposite switch (from nitrogen to helium), a reversed time course, namely a transient over saturation, was observed: PaHe + PaN2 = 1.31 (P1He + P1N2).	Nitrogen	33-41	poly(A) specific ribonuclease subunit PAN2	Homo sapiens	135-139
10842180-0	2000	Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein.	Nitrogen	13-14	prion like protein doppel	Mus musculus	0-6
7275458-8	1981	In Gp 4 nitrogen loss was persistently high (4.3-5.8 g N/day) during the whole period of observation.	Nitrogen	8-16	CD36 molecule	Homo sapiens	3-7
10960154-1	2000	The KvLQT1 and minK subunits that coassemble to form I(sK) channels, contain potential N-glycosylation sites.	Nitrogen	87-88	potassium voltage-gated channel subfamily Q member 1	Homo sapiens	4-10
12688246-2	2003	Thereby was observed a dependence on the electrophilic properties of C-1 for forming the pseudo-bases and a ring opening tendency to the amino ketones by electron-withdrawing substituents at the nitrogen atom.	Nitrogen	195-203	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	69-72
12527108-0	2003	N-glycosylation of recombinant human fucosyltransferase III is required for its in vivo folding in mammalian and insect cells.	Nitrogen	0-1	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	37-59
7334427-7	1981	Considering the chemical shift of C-1 in ethyl caffeate, the C-1 in F3 could exist as -C=N-CH3.	Nitrogen	89-90	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	34-37
12502352-3	2003	The homobivalent ligands characterized by a nitrogen-bridged atom at the tether level could be considered among the most potent and selective cholinesterase inhibitors described to date.	Nitrogen	44-52	butyrylcholinesterase	Homo sapiens	142-156
10930554-12	2000	In addition, anti-N-terminal SNRK antibody stained the nuclei of cultured rat cerebellar granule neurons.	Nitrogen	18-19	SNF related kinase	Rattus norvegicus	29-33
7334427-7	1981	Considering the chemical shift of C-1 in ethyl caffeate, the C-1 in F3 could exist as -C=N-CH3.	Nitrogen	89-90	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	61-64
6782445-1	1980	Flavodoxins are low molecular weight, FMN containing, proteins which function as electron transfer agents in a variety of microbial metabolic processes, including nitrogen fixation.	Nitrogen	163-171	formin 1	Homo sapiens	38-41
10888671-0	2000	Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages.	Nitrogen	34-35	syntaxin 7	Homo sapiens	0-10
10841784-6	2000	The N(tau)-metal ligation also occurs in Cu(II)-induced Abeta aggregation at mildly acidic pH.	Nitrogen	4-5	microtubule associated protein tau	Homo sapiens	6-9
12535336-4	2003	To study the role of amino acid transporters in long-distance transport and allocation of organic nitrogen in potato plants, a gene encoding a functional, leaf-expressed amino acid permease StAAP1 was isolated.	Nitrogen	98-106	amino acid permease 6	Solanum tuberosum	190-196
16661599-11	1980	When the hybrid pairs were compared separately, it was evident that both rate of nitrate flux and level of nitrate reductase activity affect the accumulation of reduced N by the plant.Relative to the other hybrids, hybrid D that accumulated the most reduced N and nitrate as a 23-day-old seedling had the least reduced N in grain plus stover at maturity under field conditions.	Nitrogen	169-170	nitrate reductase [NADH] 1	Zea mays	107-124
12431060-3	2002	Lipophilic cationogenic amines with at least one tertiary N atom, such as verapamil, are classical PgP-blocking agents.	Nitrogen	58-59	phosphoglycolate phosphatase	Homo sapiens	99-102
12487729-9	2002	N-alkylPP formation was found following the interaction of three porphyrinogenic xenobiotics with CYP1A2, 2B1, 2C6, 2C11 and 3A2, in amounts ranging from 0.45 to 0.07 nmol N-alkylPP nmol(-1) CYP.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	98-104
12140287-0	2002	Cytoplasmic compartmentation of Gln3 during nitrogen catabolite repression and the mechanism of its nuclear localization during carbon starvation in Saccharomyces cerevisiae.	Nitrogen	44-52	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	32-36
12140287-1	2002	Regulated intracellular localization of Gln3, the transcriptional activator responsible for nitrogen catabolite repression (NCR)-sensitive transcription, permits Saccharomyces cerevisiae to utilize good nitrogen sources (e.g. glutamine and ammonia) in preference to poor ones (e.g. proline).	Nitrogen	92-100	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	40-44
12140287-1	2002	Regulated intracellular localization of Gln3, the transcriptional activator responsible for nitrogen catabolite repression (NCR)-sensitive transcription, permits Saccharomyces cerevisiae to utilize good nitrogen sources (e.g. glutamine and ammonia) in preference to poor ones (e.g. proline).	Nitrogen	203-211	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	40-44
10773339-0	2000	Distribution of the Mo-enzymes aldehyde oxidase, xanthine dehydrogenase and nitrate reductase in maize (Zea mays L.) nodal roots as affected by nitrogen and salinity.	Nitrogen	144-152	nitrate reductase [NADH] 1	Zea mays	76-93
10836977-4	2000	Rabbit kidney CA IV had two N-glycosylation sites and was sialated, the apparent molecular mass increasing by at least 11 to approximately 45 kDa in the cortex.	Nitrogen	28-29	carbonic anhydrase 4	Oryctolagus cuniculus	14-19
10799523-1	2000	GATA family activators (Gln3p and Gat1p) and repressors (Dal80p and Deh1p) regulate nitrogen catabolite repression (NCR)-sensitive transcription in Saccharomyces cerevisiae presumably via their competitive binding to the GATA sequences upstream of NCR-sensitive genes.	Nitrogen	84-92	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	24-29
10799523-2	2000	Ure2p, which is not a GATA family member, inhibits Gln3p/Gat1p from functioning in the presence of good nitrogen sources.	Nitrogen	104-112	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	51-56
6970196-6	1980	C1q contained hydroxyproline, hydroxylysine, a high percentage of glycine and approximately 9% carbohydrate and 14.8% nitrogen.	Nitrogen	118-126	complement C1q A chain	Homo sapiens	0-3
10807583-6	2000	Cellubrevin, an analog of the vesicle soluble N-ethyl malemide-sensitive factor attachment protein (SNAP) receptor (v-SNARE) synaptobrevin, is highly enriched in H(+)-ATPase-rich cells of the epididymis and vas deferens, and tetanus toxin treatment markedly inhibited bafilomycin-sensitive proton secretion by 64.3+/-9.0% in the proximal vas deferens.	Nitrogen	46-47	vesicle associated membrane protein 3	Homo sapiens	0-11
12218311-9	2002	RESULTS: Plasma NPY concentrations were inversely correlated with the serum urea nitrogen levels (r = -0.32) as well as protein catabolic rate (PCR) (r = -0.28).	Nitrogen	81-89	neuropeptide Y	Homo sapiens	16-19
7378362-3	1980	Upon irradiation of 7-cis-rhodopsin at liquid nitrogen temperature (-190 degrees C) with blue light, its spectrum shifted to the longer wavelengths, indicating the formation of a bathoproduct.	Nitrogen	46-54	rhodopsin	Bos taurus	26-35
12191695-3	2002	The microparticles were formed by atomization of an aqueous feed solution containing insulin beneath the surface of a cryogenic liquid (e.g. liquid nitrogen).	Nitrogen	148-156	insulin	Bos taurus	85-92
12067565-2	2002	They can be metabolised to reactive intermediates via N-hydroxylation catalysed by cytochrome P450 1A2, followed by conjugation of the resulting N-hydroxyl group by N-acetyltransferase (NAT) or sulfotransferase (SULT).	Nitrogen	54-55	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	83-102
10764841-3	2000	With this approach the presence of two triglucosylated-N-linked oligosaccharides in vesicular stomatis virus (VSV) G protein formed by castanospermine-treated CHO cells or the glucosidase I deficient Lec23 mutant could be clearly demonstrated and an even more pronounced change in migration was observed upon endomannosidase treatment of their more heavily N-glycosylated lysosomal membrane glycoproteins.	Nitrogen	55-56	mannosidase endo-alpha	Homo sapiens	309-324
12165425-2	2002	Under nitrogen-rich conditions, the GATA family transcriptional activators, Gln3 and Gat1, form complexes with Ure2, and are localized to the cytoplasm, which decreases NCR-sensitive expression.	Nitrogen	6-14	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	76-80
7419336-4	1980	Mean daily Nitrogen loss was significantly lower (P &lt; 0.05) in Gps 3 and 4 than in Gps 1 and 2.	Nitrogen	11-19	CD36 molecule	Homo sapiens	66-77
12165425-3	2002	Under nitrogen-limiting conditions, Gln3 and Gat1 are dephosphorylated, move from the cytoplasm to the nucleus, in wild-type but not rna1 and srp1 mutants, and increase expression of NCR-sensitive genes.	Nitrogen	6-14	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	36-40
12130708-5	2002	OFQ/N pretreatment resulted in translocation of PKC-alpha, G protein-coupled receptor kinase 2 (GRK2) and GRK3 from the cytosol to the membrane, and this translocation was also blocked by chelerythrine.	Nitrogen	4-5	G protein-coupled receptor kinase 3	Homo sapiens	106-110
10758005-5	2000	The level of N-sulfation increased from 40% in control cells to 60% and 80%, respectively, in NDST-1 and NDST-2 transfected cells.	Nitrogen	13-14	N-deacetylase and N-sulfotransferase 1	Homo sapiens	94-100
737186-8	1978	funtion at C-2 promotes binding, both covalent and electrostatic, presumably by kinetically facilitating the approach between positively charged nitrogen and DNA.	Nitrogen	145-153	complement C2	Homo sapiens	11-14
10845459-2	2000	The EILP (elicitor inducible LRR protein) gene encodes 95 kDa protein, which consists of a putative membrane spanning region, 28 leucine-rich repeats and some N-linked glycosylation sites, and shows high homology to Cf-2/Cf-5 family genes.	Nitrogen	159-160	probable leucine-rich repeat receptor-like protein kinase At1g35710	Nicotiana tabacum	4-8
10845459-2	2000	The EILP (elicitor inducible LRR protein) gene encodes 95 kDa protein, which consists of a putative membrane spanning region, 28 leucine-rich repeats and some N-linked glycosylation sites, and shows high homology to Cf-2/Cf-5 family genes.	Nitrogen	159-160	probable leucine-rich repeat receptor-like protein kinase At1g35710	Nicotiana tabacum	10-40
10729359-11	2000	Moreover, the N-dealkylation pathways of deprenyl are inhibited by 4-methylpyrazole and disulfiram, two CYP2E1 inhibitors.	Nitrogen	14-15	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	104-110
12070712-11	2002	GM-CSF/IL-2 therapy seems to induce an immune suppressive stage compared to GM-CSF alone affecting cytotoxic mononuclear cells and B cells, which might be mediated through the neopterin metabolic pathway or other inducible immune suppressive factors such as reactive oxygen and nitrogen intermediates.	Nitrogen	278-286	colony stimulating factor 2	Homo sapiens	0-6
12065445-0	2002	Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes.	Nitrogen	55-56	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	36-42
12086682-10	2002	These data support the hypothesis that n-LDL increases O(2)(*-), which scavenges *NO, and suggest that n-LDL uncouples eNOS activity by decreasing the association of hsp90 as an initial step in signaling eNOS to generate O(2)(*-).	Nitrogen	39-40	heat shock protein 90 alpha family class A member 1	Homo sapiens	166-171
12118878-0	2002	The soybean GmN6L gene encodes a late nodulin expressed in the infected zone of nitrogen-fixing nodules.	Nitrogen	80-88	nodulin 6l	Glycine max	12-17
12118878-8	2002	Homology between GmN6L and FluG, a protein involved in signaling in Aspergillus nidulans, suggests that GmN6L may play a role in communication between the host and microsymbionts during symbiotic nitrogen fixation.	Nitrogen	196-204	nodulin 6l	Glycine max	17-22
12118878-8	2002	Homology between GmN6L and FluG, a protein involved in signaling in Aspergillus nidulans, suggests that GmN6L may play a role in communication between the host and microsymbionts during symbiotic nitrogen fixation.	Nitrogen	196-204	nodulin 6l	Glycine max	104-109
10702405-9	2000	At day 10, eNOS-/- mice had higher levels of blood urea nitrogen than WT mice (P &lt; 0.02), although proteinuria was comparable.	Nitrogen	56-64	nitric oxide synthase 3, endothelial cell	Mus musculus	11-15
10696718-0	2000	Benthic fluxes of cadmium, lead, copper and nitrogen species in the northern Adriatic Sea in front of the River Po outflow, Italy.	Nitrogen	44-52	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	86-89
31359-9	1978	Unlike cathepsin B, the new cathepsin scarcely hydrolyzes N-substituted derivatives of arginine.	Nitrogen	58-59	cathepsin B	Rattus norvegicus	7-18
10655215-7	2000	Because expression of the GPR1 gene is known to be induced by nitrogen starvation, the Gpr1 receptor may serve as a dual sensor of abundant carbon source (sugar ligand) and nitrogen starvation.	Nitrogen	62-70	Gpr1p	Saccharomyces cerevisiae S288C	26-30
10655215-7	2000	Because expression of the GPR1 gene is known to be induced by nitrogen starvation, the Gpr1 receptor may serve as a dual sensor of abundant carbon source (sugar ligand) and nitrogen starvation.	Nitrogen	62-70	Gpr1p	Saccharomyces cerevisiae S288C	87-91
10655215-7	2000	Because expression of the GPR1 gene is known to be induced by nitrogen starvation, the Gpr1 receptor may serve as a dual sensor of abundant carbon source (sugar ligand) and nitrogen starvation.	Nitrogen	173-181	Gpr1p	Saccharomyces cerevisiae S288C	26-30
12135569-2	2002	Bacterial PII is regulated by covalent modification and binding to effector molecules in response to the nitrogen/carbon status of the cell and appropriately coordinates the activity of glutamine synthetase and the transcription of a nitrogen sensitive regulon.	Nitrogen	105-113	hypothetical protein	Arabidopsis thaliana	186-206
690755-0	1978	Treatment of complete ornithine transcarbamylase deficiency with nitrogen-free analogues of essential amino acids.	Nitrogen	65-73	ornithine transcarbamylase	Homo sapiens	22-48
12022880-6	2002	This study establishes the structure of the Ni site in resting Ni-ARD as containing a six coordinate Ni site composed of O/N-donor ligands including 3-4 histidine residues, demonstrates that the substrate binds to the Ni center in a bidentate fashion by displacing two ligands, at least one of which is a histidine ligand, and provides insight into the mechanism of catalysis employed by a Ni-containing dioxygenase.	Nitrogen	44-45	acireductone dioxygenase 1	Homo sapiens	63-69
11988075-8	2002	Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3.	Nitrogen	5-6	fatty acid desaturase 2	Rattus norvegicus	56-67
11988075-8	2002	Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3.	Nitrogen	27-28	fatty acid desaturase 2	Rattus norvegicus	56-67
11988075-8	2002	Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3.	Nitrogen	27-28	fatty acid desaturase 2	Rattus norvegicus	56-67
11988075-8	2002	Evidence is therefore presented that the same rat Delta6-desaturase catalyses not only the conversion of C(18:3) n-3 to C(18:4) n-3, but also the conversion of C(24:5) n-3 to C(24:6) n-3.	Nitrogen	27-28	fatty acid desaturase 2	Rattus norvegicus	56-67
10655215-7	2000	Because expression of the GPR1 gene is known to be induced by nitrogen starvation, the Gpr1 receptor may serve as a dual sensor of abundant carbon source (sugar ligand) and nitrogen starvation.	Nitrogen	173-181	Gpr1p	Saccharomyces cerevisiae S288C	87-91
11013410-1	2000	The major pathway of bioactivation of procarcinogenic heterocyclic aromatic amines (HCAs) is cytochrome P450 1A2 (CYP1A2)-catalyzed N-hydroxylation and subsequent esterification by O-acetyltransferase (O-AT).	Nitrogen	132-133	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	93-112
11013410-1	2000	The major pathway of bioactivation of procarcinogenic heterocyclic aromatic amines (HCAs) is cytochrome P450 1A2 (CYP1A2)-catalyzed N-hydroxylation and subsequent esterification by O-acetyltransferase (O-AT).	Nitrogen	132-133	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	114-120
212731-2	1978	The EPR spectrum of bleached ceruloplasmin has a seven-line superhyperfine structure in the g : formula: (see text) region that is attributed to the presence of three nitrogen-donor type 2 copper ligands.	Nitrogen	167-175	ceruloplasmin	Homo sapiens	29-42
10611304-5	1999	Poor nitrogen quality activates the nitrogen discrimination pathway, which is controlled by the complex of the transcriptional repressor Ure2p and activator Gln3p.	Nitrogen	5-13	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	157-162
10611304-5	1999	Poor nitrogen quality activates the nitrogen discrimination pathway, which is controlled by the complex of the transcriptional repressor Ure2p and activator Gln3p.	Nitrogen	36-44	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	157-162
12051746-1	2002	Tyrosinase, the key enzyme of melanin biosynthesis, is inactivated in melanoma cells following the incubation with the imino-sugar N-butyldeoxynojirimycin, an inhibitor of the endoplasmic reticulum N-glycosylation processing.	Nitrogen	131-132	tyrosinase	Mus musculus	0-10
11867635-6	2002	All three potential N-glycosylation sites in M2BP-1,2 and all four in M2BP-3,4 were found to be occupied.	Nitrogen	20-21	galectin 3 binding protein	Homo sapiens	45-49
11978125-4	2002	UV-vis spectrophotometry and mass spectroscopy were used to show that Cbl(I) reduces NO to form Cbl(II)-NO and N(2)O and N(2), and this reaction is involved in the cyclic voltammetry of cobalamin in the presence of excess NO where a catalytic reduction of NO occurs involving the cycling of Cbl(II)-NO/Cbl(I).	Nitrogen	111-115	Cbl proto-oncogene	Homo sapiens	70-73
11978125-4	2002	UV-vis spectrophotometry and mass spectroscopy were used to show that Cbl(I) reduces NO to form Cbl(II)-NO and N(2)O and N(2), and this reaction is involved in the cyclic voltammetry of cobalamin in the presence of excess NO where a catalytic reduction of NO occurs involving the cycling of Cbl(II)-NO/Cbl(I).	Nitrogen	111-115	Cbl proto-oncogene	Homo sapiens	291-301
639429-4	1978	The greater N-demethylation was found in a subject with lower plasma cholinesterase activity.	Nitrogen	12-13	butyrylcholinesterase	Homo sapiens	69-83
11973406-2	2002	Insulin-like growth factor I (IGF-I) is believed to improve nitrogen balance and have anabolic effects, and it has been proposed as one of the mediators of vascular smooth muscle proliferation.	Nitrogen	60-68	insulin-like growth factor 1	Rattus norvegicus	0-28
11973406-2	2002	Insulin-like growth factor I (IGF-I) is believed to improve nitrogen balance and have anabolic effects, and it has been proposed as one of the mediators of vascular smooth muscle proliferation.	Nitrogen	60-68	insulin-like growth factor 1	Rattus norvegicus	30-35
10641793-5	1999	i.e. by attaching either an extra propargyl or a methyl group to the nitrogen atom, the potency of inhibition of MAO-B activity was drastically reduced and inhibition of MAO-A activity substantially increased.	Nitrogen	69-77	monoamine oxidase A	Homo sapiens	170-175
10536368-3	1999	Site-directed mutagenesis was used to delete N-linked glycosylation sites from a chimeric protein, TNFR-IgG1.	Nitrogen	45-46	TNF receptor superfamily member 1A	Homo sapiens	99-103
10607429-3	1999	In contrast to the Thy-1 antigen of most other species, guinea pig Thy-1 has a much higher molecular weight, which is due to a more extensive N-linked glycosylation, bringing the molecular weight of the total antigen up to 36 kDa.	Nitrogen	142-143	thy-1 membrane glycoprotein	Cavia porcellus	67-72
12026079-5	2002	Assuming a base temperature (Tb) of 10 degrees C, N uptake temperature sum (UTS) = sigma(Ts - Tb)/24 (degrees CdN, degree day units of N uptake).	Nitrogen	50-51	5', 3'-nucleotidase, cytosolic	Homo sapiens	110-113
12028572-9	2002	Requirement of Rar1- like gene for N-mediated resistance to TMV and some powdery mildew resistance genes in barley provide the first example of converging points in the disease resistance signalling pathways mediated by TIR-NBS-LRR and CC-NBS-LRR proteins.	Nitrogen	35-36	cysteine and histidine-rich domain-containing protein RAR1-like	Nicotiana tabacum	15-19
148551-3	1978	The fixation of molecular nitrogen in water layers was characterized by three maxima: 5.0 mcg N per litre per 4 hours (surface); 4.2 mcg N per litre per 4 hours (metalimnion) and 2.8 mcg N per litre per 4 hours (at bottom).	Nitrogen	26-34	PER3 pseudogene 1	Homo sapiens	106-111
11948665-6	2002	Moreover, 1-hr exposure to N+Glu- led to a substantial and 4-hr exposure led to a total disappearance of immunostaining for MAP-2 and NPY but not for GFAP; indicating that neurons are the primary cell-type damaged by oxygen-glucose deprivation.	Nitrogen	27-28	microtubule-associated protein 2	Rattus norvegicus	124-129
12152307-0	2002	[Method for determining nitrogen-containing cationic surface-active agents using butyrylcholinesterase].	Nitrogen	24-32	butyrylcholinesterase	Homo sapiens	81-102
10644005-6	1999	The incorporation of 3H-glucosamine, as a marker of N-glycosylation, into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	52-53	tyrosinase	Mus musculus	74-84
10644005-6	1999	The incorporation of 3H-glucosamine, as a marker of N-glycosylation, into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	147-148	tyrosinase	Mus musculus	74-84
10537138-0	1999	Role of N-linked glycosylation on the function and expression of the human secretin receptor.	Nitrogen	8-9	secretin receptor	Homo sapiens	75-92
10537138-2	1999	The human secretin receptor (hSR) is a glycoprotein consisting of 440 amino acids, of which there are 5 putative N-linked glycosylation sites at positions Asn72, Asn100, Asn106, Asn128 (N-terminal ectodomain), and Asn291 (second exoloop).	Nitrogen	113-114	secretin receptor	Homo sapiens	10-27
148551-3	1978	The fixation of molecular nitrogen in water layers was characterized by three maxima: 5.0 mcg N per litre per 4 hours (surface); 4.2 mcg N per litre per 4 hours (metalimnion) and 2.8 mcg N per litre per 4 hours (at bottom).	Nitrogen	26-34	PER3 pseudogene 1	Homo sapiens	149-154
10533053-9	1999	AsECM contained significant amounts of laminin and fibronectin, and pure fibronectin and laminin also protected neurons against RO/NS-induced damage in the same manner as AsECM.	Nitrogen	131-133	fibronectin 1	Rattus norvegicus	73-84
148551-3	1978	The fixation of molecular nitrogen in water layers was characterized by three maxima: 5.0 mcg N per litre per 4 hours (surface); 4.2 mcg N per litre per 4 hours (metalimnion) and 2.8 mcg N per litre per 4 hours (at bottom).	Nitrogen	26-34	PER3 pseudogene 1	Homo sapiens	149-154
11852060-4	2002	Monosaccharide composition analyses and specific lectin blots suggested that the tau in AD brain was glycosylated mainly through N-linkage.	Nitrogen	129-130	microtubule associated protein tau	Homo sapiens	81-84
403073-3	1977	A double mutant (prc 1- leu2-) lacking carboxypeptidase Y and auxotrophic for leucine is able to grow on the peptide benzyloxycarbonylglycylleucine (Cbz-Gly-Leu) as sole nitrogen source, indicating the existence of a second carboxypeptidase.	Nitrogen	170-178	carboxypeptidase C PRC1	Saccharomyces cerevisiae S288C	17-22
11800487-5	2002	Measurements of light-dependent oxygen production (LDOP) and activity levels of nitrogen assimilation enzymes, including nitrite reductase (NiR) and glutamine synthetase (GS) in immobilized cells, determined under photorespiration stimulating conditions, are shown that support this explanation.	Nitrogen	80-88	uncharacterized protein	Chlamydomonas reinhardtii	140-143
10536042-9	1999	These results indicate that GPT function is essential in early embryogenesis and suggest that N-glycosylation is needed for the viability of cells comprising the peri-implantation stage embryo.	Nitrogen	94-95	glutamic pyruvic transaminase, soluble	Mus musculus	28-31
10530928-12	1999	In the serotonin 5-HT1A receptor model, the benzamide phenyl rings of both enantiomers were involved in hydrophobic face-to-face interactions with Phe112 in TM3, while their protonated nitrogen atoms formed a reinforced electrostatic interaction with Asp116 in TM3.	Nitrogen	185-193	5-hydroxytryptamine receptor 1A	Homo sapiens	17-32
830400-3	1977	Since N-hydroxylation of 2-FAA by hepatic microsomes is catalyzed by the mixed-function oxidase containing cytochrome P-450 or the 2-methylcholanthrene-inducible cytochrome P1-450, we examined whether these cytochromes are present in mammary microsomes.	Nitrogen	6-7	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	173-179
10483905-2	1999	An increase of synthesis greater than the increase of breakdown resulted in improved nitrogen retention in the IGF-1 group.	Nitrogen	85-93	insulin-like growth factor 1	Rattus norvegicus	111-116
11809814-0	2002	Convergence of TOR-nitrogen and Snf1-glucose signaling pathways onto Gln3.	Nitrogen	19-27	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	69-73
11809814-4	2002	Gln3 is a GATA-type transcription factor of nitrogen catabolite-repressible (NCR) genes.	Nitrogen	44-52	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
1010799-9	1976	N-Acylation of the amino group at C-1 or at C-4 gave virtually inactive products.	Nitrogen	0-1	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	34-37
11809814-5	2002	Previous observations indicate that the quality of nitrogen sources controls the phosphorylation and cytoplasmic retention of Gln3 via the target of rapamycin (TOR) protein.	Nitrogen	51-59	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	126-130
11809814-7	2002	Our data show that glucose and nitrogen signaling pathways converge onto Gln3, which may be critical for both nutrient sensing and starvation responses.	Nitrogen	31-39	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	73-77
1010799-9	1976	N-Acylation of the amino group at C-1 or at C-4 gave virtually inactive products.	Nitrogen	0-1	complement C4A (Rodgers blood group)	Homo sapiens	44-47
132455-4	1976	In 7 GH-deficient children and 3 adults with myotonic dystrophy, we measured the capacity of human GH (hGH), pGH, and pGH plasmin digests to cause: a) the retention of N, P, K, Na, and Cl; b) a rise in plasma free fatty acids; c) a fall in plasma alpha-amino NL d) impaired glucose tolerance; and e) hyperinsulinemia.	Nitrogen	168-169	gamma-glutamyl hydrolase	Homo sapiens	103-106
18763064-7	2002	There is a cis-activating GATA motif in ENH of DLA-EIAV and EIAV L. Two N-linked glycosylation sites disappeared in DLA-EIAV Gp90 in comparison with that of EIAV L. A bHLH transcription factor binding consensus sequence was found in LTR of DLA-EIAV but not in EIAV L. Furthermore, there is a mutation in the stem of DLA-EIAV TAR resulting in formation of a uridine tuber.	Nitrogen	41-42	galectin 3 binding protein	Homo sapiens	125-129
11784114-4	2002	Various lines of evidences have verified this intercellular signal transmission, but there also have been implications that expression of Dl or Ser interferes cell-autonomously with the ability of the cell to receive N signal, implying that N and its ligands may interact in the same cell.	Nitrogen	217-218	serrate, RNA effector molecule	Homo sapiens	144-147
11784114-9	2002	In vivo overexpression study suggests that the cell-autonomous function of Dl and Ser is independent of the ligand specificity and may be modulated by Fringe (Fg), which inhibits the formation of the cell-autonomous Dl/N or Ser/N complex.	Nitrogen	219-220	serrate, RNA effector molecule	Homo sapiens	82-85
11784114-9	2002	In vivo overexpression study suggests that the cell-autonomous function of Dl and Ser is independent of the ligand specificity and may be modulated by Fringe (Fg), which inhibits the formation of the cell-autonomous Dl/N or Ser/N complex.	Nitrogen	219-220	serrate, RNA effector molecule	Homo sapiens	224-227
16233323-4	2002	When grown on arginine as the sole nitrogen source, the put2 disruptant showed a significant decrease in cell viability after freezing despite the high proline and arginine contents.	Nitrogen	35-43	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	56-60
24271418-1	1976	The catalase inhibitor 3-amino-1,2,4-triazole causes an increase in dopamine-beta-hydroxylase (DBH) activity, as do other nitrogen-containing heterocyclics.	Nitrogen	122-130	dopamine beta-hydroxylase	Homo sapiens	68-93
11814014-2	2001	The present work was performed to clarify the structures of the glycans linked to the five N-glycosylation sites in lactoferrin-a and to compare them with those of glycans linked to lactoferrin-b.	Nitrogen	91-92	lactotransferrin	Bos taurus	116-127
24271418-1	1976	The catalase inhibitor 3-amino-1,2,4-triazole causes an increase in dopamine-beta-hydroxylase (DBH) activity, as do other nitrogen-containing heterocyclics.	Nitrogen	122-130	dopamine beta-hydroxylase	Homo sapiens	95-98
24271418-4	1976	The nitrogen-containing compounds, and denatured catalase, protect DBH from inhibition by copper.	Nitrogen	4-12	dopamine beta-hydroxylase	Homo sapiens	67-70
1250313-7	1976	The hyperammonemia of Reye"s syndrome apparently results from excess waste nitrogen that overwhelms the ability of reduced ornithine transcarbamylase (and occasionally carbamyl phosphate synthetase) to detoxify the ammonia load.	Nitrogen	75-83	ornithine transcarbamylase	Homo sapiens	123-149
11716519-2	2001	Transcription of YVH1 is induced by lowering temperature and nitrogen starvation.	Nitrogen	61-69	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	17-21
164411-6	1975	The specific toxicity of the enterotoxin was about 1,900 mouse mean lethal doses per mg of calculated nitrogen.	Nitrogen	102-110	cpe	Clostridium perfringens	29-40
11690653-9	2001	In addition, the present study demonstrates that the recombinant hST3Gal I polypeptides transiently expressed in COS-7 cells are glycosylated with complex and high mannose type glycans on each of the five potential N-glycosylation sites.	Nitrogen	215-216	tumor-suppressor, HELA cell type	Homo sapiens	65-69
11587526-1	2001	The amino acid permease Bap2p in Saccharomyces cerevisiae mediates a major part of the uptake of leucine, isoleucine, and valine from media containing a preferred nitrogen source.	Nitrogen	163-171	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	24-29
4464661-0	1974	[Nitrogen-fixation in the coastal waters of the Baltic Sea].	Nitrogen	1-9	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	55-58
11587526-3	2001	Here we show that Bap2p is subject to a starvation-induced degradation upon rapamycin treatment or cultivation with proline as the sole nitrogen source.	Nitrogen	136-144	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	18-23
11443120-7	2001	Secretion of AChE(T) was partially restored by co-expression with Q(N), a secretable protein containing a proline-rich attachment domain (PRAD); Q(N) organized PRAD-linked tetramers, except for the N-glycosylated mutants.	Nitrogen	68-69	acetylcholinesterase	Rattus norvegicus	13-17
5140009-2	1971	Studies on some potentially antitumor active androstane compounds containing C-17 nitrogen mustard functions.	Nitrogen	82-90	cytokine like 1	Homo sapiens	77-81
11574074-4	2001	The major N-linked sugar chains of human urinary thrombomodulin were found to be monosialo- and disialofucosylbiantennary chains, while the major O-linked sugar chain was +/-Siaalpha2-3Galbeta1-3(+/-Siaalpha2-6)GalNAc.	Nitrogen	10-11	thrombomodulin	Homo sapiens	49-63
16656715-1	1967	Primary and secondary metabolites of inorganic nitrogen metabolism were evaluated as inhibitors of nitrate reductase (EC 1.6.6.1) induction in green leaf tissue of corn seedlings.	Nitrogen	47-55	nitrate reductase [NADH] 1	Zea mays	99-116
11544325-0	2001	N-linked glycosylations at Asn(26) and Asn(114) of human MD-2 are required for toll-like receptor 4-mediated activation of NF-kappaB by lipopolysaccharide.	Nitrogen	0-1	toll like receptor 4	Homo sapiens	79-99
11544325-7	2001	These observations demonstrate that hMD-2 undergoes N-linked glycosylation at Asn(26) and Asn(114), and that these glycosylations are crucial for TLR4-mediated signal transduction of LPS.	Nitrogen	52-53	interferon regulatory factor 6	Homo sapiens	183-186
16656715-5	1967	Because of the short half-life of nitrate reductase, inhibitors of protein synthesis in general could still achieve differential regulation of nitrogen metabolism.	Nitrogen	143-151	nitrate reductase [NADH] 1	Zea mays	34-51
11504859-8	2001	However, when the N-glycosylation signal is eliminated, the nAChR containing the N. haje sequence is inhibited by alpha-BTX with a potency that is comparable to that in mammals.	Nitrogen	18-19	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	60-65
5603093-0	1967	[An effect of insulin on the content of nitrogen compounds and the enzyme activity of cattle fore-stomach].	Nitrogen	40-48	insulin	Bos taurus	14-21
11408486-1	2001	Gln3p is one of two well characterized GATA family transcriptional activation factors whose function is regulated by the nitrogen supply of the cell.	Nitrogen	121-129	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-5
11408486-2	2001	When nitrogen is limiting, Gln3p and Gat1p are concentrated in the nucleus where they bind GATA sequences upstream of nitrogen catabolite repression (NCR)-sensitive genes and activate their transcription.	Nitrogen	5-13	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	27-32
11408486-2	2001	When nitrogen is limiting, Gln3p and Gat1p are concentrated in the nucleus where they bind GATA sequences upstream of nitrogen catabolite repression (NCR)-sensitive genes and activate their transcription.	Nitrogen	118-126	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	27-32
13600026-0	1958	Nitrogen retention in man produced by chymotrypsin digests of bovine somatotropin.	Nitrogen	0-8	somatotropin	Bos taurus	69-81
11481458-4	2001	The extracellular domain of Porimin contains many O-linked and seven N-linked glycosylation sites that define it as a new member of the mucin family.	Nitrogen	69-70	transmembrane protein 123	Homo sapiens	28-35
33722647-7	2021	Plasma concentrations of blood urea nitrogen (BUN) were significantly enhanced at 24 h, 72 h and 1 week, and creatinine (Cr) was increased at 24 h after reperfusion, which were changes reduced by EPO.	Nitrogen	36-44	erythropoietin	Rattus norvegicus	196-199
11526439-5	2001	Here we show that N-terminal phosphorylation of c-Jun, the other main partner of c-Fos in induced AP-1 complexes is not required for programmed cell death during retinal development in vivo and is also dispensable for photoreceptor apoptosis induced by the exogenous stimuli "excessive light" and N-nitroso-N-methylurea (MNU).	Nitrogen	18-19	FBJ osteosarcoma oncogene	Mus musculus	81-86
11488931-6	2001	239, 340-348) we produced in the yeast Saccaromyces cerevisiae an N-deglycosylated form of soluble beta4gal-T1 that was much more homogeneous than the human enzyme, as it displayed only two isoforms when analysed by IEF as compared to 13 isoforms for the native beta4gal-T1.	Nitrogen	66-67	beta-1,4-galactosyltransferase 1	Homo sapiens	99-110
11488931-6	2001	239, 340-348) we produced in the yeast Saccaromyces cerevisiae an N-deglycosylated form of soluble beta4gal-T1 that was much more homogeneous than the human enzyme, as it displayed only two isoforms when analysed by IEF as compared to 13 isoforms for the native beta4gal-T1.	Nitrogen	66-67	beta-1,4-galactosyltransferase 1	Homo sapiens	262-273
11463327-2	2001	The key reactions are an internal displacement by nitrogen to introduce the cis amino group at C-4 and the methylation of an enolate at C-5.	Nitrogen	50-58	complement C4A (Rodgers blood group)	Homo sapiens	95-98
11463327-2	2001	The key reactions are an internal displacement by nitrogen to introduce the cis amino group at C-4 and the methylation of an enolate at C-5.	Nitrogen	50-58	complement C5	Homo sapiens	136-139
11353758-5	2001	Among the 12 cDNA-expressed CYP enzymes examined, CYP2B6, CYP2C9, and CYP3A4 showed high activities for the N-demethylation of both enantiomers at the substrate concentration of 1 mM.	Nitrogen	15-16	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	58-64
11353758-7	2001	Also, the intrinsic clearance (CL(int): V(max)/K(m)) of CYP2B6 for the N-demethylation of both enantiomers were 7 to 13 times higher than those of CYP2C9 and CYP3A4.	Nitrogen	71-72	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	147-153
33879640-6	2021	Previously, we have shown that in C. glabrata Gln3, but not Gat1, has a major role in nitrogen assimilation as opposed to what has been observed in S. cerevisiae in which both factors regulate NCR-sensitive genes.	Nitrogen	86-94	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	46-50
11344304-5	2001	Using gain-of-function experiments, we further demonstrate that ectopic wild-type and truncated Neur proteins can interfere with multiple N-controlled aspects of eye development, including both neur-dependent and neur-independent processes.	Nitrogen	96-97	neuralized	Drosophila melanogaster	194-198
11344304-5	2001	Using gain-of-function experiments, we further demonstrate that ectopic wild-type and truncated Neur proteins can interfere with multiple N-controlled aspects of eye development, including both neur-dependent and neur-independent processes.	Nitrogen	96-97	neuralized	Drosophila melanogaster	213-217
10823196-2	1999	The major reason appears to be a distortion of the conformer in which the C-2-Sn bond is synclinal to the nitrogen lone pair.	Nitrogen	106-114	complement C2	Homo sapiens	74-77
34015111-0	2022	Characteristics of purified Anti-beta2GPI IgG N-glycosylation associate with thrombotic, obstetric, and catastrophic antiphospholipid syndrome.	Nitrogen	46-47	apolipoprotein H	Homo sapiens	33-41
11354385-0	2001	2-Aryl indole NK1 receptor antagonists: optimisation of the 2-aryl ring and the indole nitrogen substituent.	Nitrogen	87-95	tachykinin receptor 1	Homo sapiens	14-26
34052536-2	2021	Hierarchically porous cobalt phosphide/N-doped nanotubular carbon networks (CoP/NCNs) that have all the features were fabricated in this work.	Nitrogen	39-40	caspase recruitment domain family member 16	Homo sapiens	76-79
11344045-9	2001	Caspase activation and apoptosis induced by nitrogen-containing bisphosphonates are likely to be the consequence of the loss of geranylgeranylated rather than farnesylated proteins, because the ability to cause apoptosis and caspase activation was mimicked by GGTI-298, a specific inhibitor of protein geranylgeranylation, whereas FTI-277, a specific inhibitor of protein farnesylation, had no effect on apoptosis or caspase activity.	Nitrogen	44-52	protein geranylgeranyltransferase type I subunit beta	Homo sapiens	260-264
10542133-4	1999	The deduced IPM 200 core protein contains a putative transmembrane domain, two EGF-like repeats, numerous N- and O-linked glycosylation consensus sequences and one consensus sequence for glycosaminoglycan attachment.	Nitrogen	106-107	interphotoreceptor matrix proteoglycan 2	Homo sapiens	12-19
33465630-11	2021	Our results suggest that application of corn cob pieces, alone or in combination with lactic acid, as effluent cover could effectively mitigate NH3 volatilization and retain N, thereby enhancing the fertilizer value of the stored dairy effluent and co-applied as a soil amendment after two months open storage.	Nitrogen	144-145	metabolism of cobalamin associated B	Homo sapiens	45-48
10406940-0	1999	The relevance of N-linked glycosylation to the binding of a ligand to guanylate cyclase C.	Nitrogen	17-18	natriuretic peptide receptor 3	Homo sapiens	70-89
10359460-9	1999	In conclusion, these data indicate that while both CYP isoforms readily catalyze both metabolic routes in vitro, CYP1A2 and CYP3A4 are more important in N-demethylation and N-oxidation, respectively.	Nitrogen	153-154	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	113-119
11401696-1	2001	In Saccharomyces cerevisiae, the ability to use proline as a nitrogen source requires the Put3p transcriptional regulator, which turns on the expression of the proline utilization genes, PUT1 and PUT2, in the presence of the inducer proline and in the absence of preferred nitrogen sources.	Nitrogen	61-69	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	196-200
11401696-1	2001	In Saccharomyces cerevisiae, the ability to use proline as a nitrogen source requires the Put3p transcriptional regulator, which turns on the expression of the proline utilization genes, PUT1 and PUT2, in the presence of the inducer proline and in the absence of preferred nitrogen sources.	Nitrogen	273-281	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	196-200
11226227-0	2001	Arabidopsis cyt1 mutants are deficient in a mannose-1-phosphate guanylyltransferase and point to a requirement of N-linked glycosylation for cellulose biosynthesis.	Nitrogen	114-115	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	12-16
11226227-6	2001	Mutant cyt1 embryos are deficient in N-glycosylation and have an altered composition of cell wall polysaccharides.	Nitrogen	37-38	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	7-11
33682282-8	2021	With a composition of Zn 3 (mIm) 5 (OH), ZIF-EC1 exhibits high N and Zn densities.	Nitrogen	63-64	Susceptibility to lysis by alloreactive natural killer cells	Homo sapiens	45-48
11226227-8	2001	Characteristic aspects of the cyt1 phenotype, including radial swelling and accumulation of callose, can be mimicked with the inhibitor of N-glycosylation, tunicamycin.	Nitrogen	139-140	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	30-34
10232056-16	1999	These results suggest that since no dramatic changes in the levels of protein were observed in the muscle and liver, there is an alteration in glutaminase and glutamine synthetase activity in order to maintain nitrogen metabolism in the initial phase of hypoxic exposure.	Nitrogen	210-218	glutaminase	Rattus norvegicus	143-154
34040623-6	2021	Such studies on the nutrient interaction pathways suggest that an MYB-like transcription factor, phosphate starvation response 1 (PHR1), acts as a master regulator of N, P, S, Fe, and Zn homeostasis.	Nitrogen	167-168	phosphate starvation response 1	Arabidopsis thaliana	97-128
10191360-3	1999	We find that in brain Kv1.1, Kv1.2 and Kv1.4, which have a single consensus glycosylation site in the first extracellular interhelical domain, are N-glycosylated with sialic acid-rich oligosaccharide chains.	Nitrogen	147-148	potassium voltage-gated channel subfamily A member 1	Homo sapiens	22-27
10191360-3	1999	We find that in brain Kv1.1, Kv1.2 and Kv1.4, which have a single consensus glycosylation site in the first extracellular interhelical domain, are N-glycosylated with sialic acid-rich oligosaccharide chains.	Nitrogen	147-148	potassium voltage-gated channel subfamily A member 4	Homo sapiens	39-44
10191360-6	1999	The extent of processing of N-linked chains on Kv1.1 and Kv1.2 but not Kv1.4 channels expressed in transfected cells differs from that seen for native brain channels, reflecting the different efficiencies of transport of K+ channel polypeptides from the endoplasmic reticulum to the Golgi apparatus.	Nitrogen	28-29	potassium voltage-gated channel subfamily A member 1	Homo sapiens	47-52
10087001-0	1999	Central administration of [Phe1psi(CH2-NH)Gly2]nociceptin(1-13)-NH2 and orphanin FQ/nociceptin (OFQ/N) produce similar cardiovascular and renal responses in conscious rats.	Nitrogen	39-40	prepronociceptin	Rattus norvegicus	47-57
11168455-11	2001	Rats treated with L-NAME had significantly higher plasma levels of endotoxin (26.7 +/- 3.8 pg mL-1) and tumour necrosis factor-alpha (29.4 +/- 6.5 pg mL-1) compared with rats treated with N/S (13.2 +/- 2.7 pg mL-1 and 11.2 +/- 2.6 pg mL-1, respectively, P &lt; 0.01).	Nitrogen	20-21	L1 cell adhesion molecule	Mus musculus	94-132
11168455-11	2001	Rats treated with L-NAME had significantly higher plasma levels of endotoxin (26.7 +/- 3.8 pg mL-1) and tumour necrosis factor-alpha (29.4 +/- 6.5 pg mL-1) compared with rats treated with N/S (13.2 +/- 2.7 pg mL-1 and 11.2 +/- 2.6 pg mL-1, respectively, P &lt; 0.01).	Nitrogen	20-21	L1 cell adhesion molecule	Mus musculus	209-222
11035038-4	2001	Along with T126M, mutations H122S, N124S, and A125T were introduced to preserve the consensus sequence for N-linked glycosylation found in human AQP2.	Nitrogen	35-36	aquaporin 2	Homo sapiens	145-149
11217952-0	2001	Synthesis of novel ganglioside GM4 analogues containing N-deacetylated and lactamized sialic acid: probes for searching new ligand structures for human L-selectin.	Nitrogen	56-57	selectin L	Homo sapiens	152-162
10024536-1	1999	UDP-N-acetylglucosamine:dolichyl-phosphate N-acetylglucosamine-1-phosphate transferase (GPT) is the first enzyme in the dolichol pathway of protein N-glycosylation, and is implicated in the developmental programmes of a variety of eukaryotes.	Nitrogen	4-5	glutamic pyruvic transaminase, soluble	Mus musculus	88-91
34040623-6	2021	Such studies on the nutrient interaction pathways suggest that an MYB-like transcription factor, phosphate starvation response 1 (PHR1), acts as a master regulator of N, P, S, Fe, and Zn homeostasis.	Nitrogen	167-168	phosphate starvation response 1	Arabidopsis thaliana	130-134
10048020-1	1999	In Saccharomyces cerevisiae, the transcription factors Gln3p and Nil1p of the GATA family play a determinant role in expression of genes that are subject to nitrogen catabolite repression.	Nitrogen	157-165	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	55-60
10048020-4	1999	Gan1p is required for full expression of GLN1, GDH2 and also other nitrogen utilization genes, including GAP1, PUT4, MEP2 and GDH1.	Nitrogen	67-75	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	126-130
11575087-1	2001	This papers describes the behaviour of wetlands as a post-treatment unit for anaerobically treated sewage for the removal of organic matter, suspended solids, nutrients (nitrogen and phosphorus) and faecal coliforms.	Nitrogen	170-178	solute carrier family 35 member G1	Homo sapiens	53-57
34010766-2	2021	To occupy a presumed hydrophobic space between the pyrimidine and piperidine rings in interaction with GPR119, we replaced the linker oxygen with nitrogen.	Nitrogen	146-154	G protein-coupled receptor 119	Homo sapiens	103-109
11118203-7	2000	In PH cells, nutritional starvation for nitrogen efficiently prevents distal localization of Bud9p.	Nitrogen	40-48	Bud9p	Saccharomyces cerevisiae S288C	93-98
11118203-9	2000	In response to nitrogen starvation, asymmetric localization of Bud9p is averted, favouring Bud8p-mediated cell division at the distal pole.	Nitrogen	15-23	Bud9p	Saccharomyces cerevisiae S288C	63-68
10048020-10	1999	Ada1/Gan1p thus represents the first reported case of an accessory protein (a co-activator) linking the GATA-binding proteins Gln3p and Nil1p, mediating nitrogen-regulated transcription, to the basal transcription machinery.	Nitrogen	153-161	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	126-131
10199594-5	1999	The kinetics of the N-demethylation process by CYP1A2, 2C8, 2C19 and 2D6 were studied by fitting to Michaelis-Menten kinetics by Lineweaver-Burk plots.	Nitrogen	20-21	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	47-53
34044194-1	2021	High quantum yield 3-aminophenylboronic acid-functionalized nitrogen-doped carbon dots (GAAP-CDs) were fabricated using a simple hydrothermal route and used as a sensing probe for toxic hypochlorite (ClO-).	Nitrogen	60-68	transmembrane BAX inhibitor motif containing 4	Homo sapiens	88-92
9916684-4	1999	Conspicuously, position 234 is part of an N-glycosylation motif (Asn-Xaa-Ser/Thr), suggesting that the Asn234 to Asp substitution might occur naturally within the cell due to deglycosylation/deamidation of this amino acid by the cytosolic enzyme peptide N-glycanase.	Nitrogen	42-43	N-glycanase 1	Homo sapiens	246-265
11082042-3	2000	The deduced amino acid sequence of porcine thyroid cathepsin K predicted a 37 kDa preproenzyme, with the active site residues Cys-140, His-277 and Asn-297, and one potential N-glycosylation site.	Nitrogen	174-175	cathepsin K	Homo sapiens	51-62
33674271-0	2021	Metabolic Retroversion of Piperaquine (PQ) via Hepatic CYP-mediated N-oxidation and Reduction: not an Important Contributor to the Prolonged Elimination of PQ.	Nitrogen	68-69	peptidylprolyl isomerase G	Homo sapiens	55-58
11087350-1	2000	In an effort to gain greater insight into the molecular mechanism of the electron-transfer reactions of cytochrome b(5), the bovine cytochrome b(5)-horse cytochrome c complex has been investigated by high-resolution multidimensional NMR spectroscopy using (13)C, (15)N-labeled cytochrome b(5) expressed from a synthetic gene.	Nitrogen	233-234	cytochrome c, somatic	Equus caballus	154-166
11076970-4	2000	Expression of these genes in media containing urea or ammonia as a sole nitrogen source requires the heterodimeric bZip transcription factors Rtg1 and Rtg3 and correlates with a redistribution of the Rtg1p/Rtg3 complex from a predominantly cytoplasmic to a predominantly nuclear location.	Nitrogen	72-80	Rtg3p	Saccharomyces cerevisiae S288C	151-155
10427503-8	1999	N-glycosylated FGF-6 potently induced DNA synthesis and proliferation of human vascular endothelial cells, whereas in the absence of N-glycosylation, FGF-6 mitogenicity was substantially diminished.	Nitrogen	0-1	fibroblast growth factor 6	Homo sapiens	15-20
33674271-4	2021	The N-oxidation of PQ to PN1 was mainly mediated by CYP3A4, and PN1 can rapidly reduce back to PQ via CYP/FMO enzymes.	Nitrogen	4-5	serpin family E member 2	Homo sapiens	25-28
9886097-0	1999	Transgenic analysis of rds/peripherin N-glycosylation: effect on dimerization, interaction with rom1, and rescue of the rds null phenotype.	Nitrogen	38-39	peripherin	Mus musculus	27-37
33674271-4	2021	The N-oxidation of PQ to PN1 was mainly mediated by CYP3A4, and PN1 can rapidly reduce back to PQ via CYP/FMO enzymes.	Nitrogen	4-5	serpin family E member 2	Homo sapiens	64-67
9886097-4	1999	In this study, we investigated the role of rds/peripherin N-glycosylation.	Nitrogen	58-59	peripherin	Mus musculus	47-57
11049868-4	2000	Intraperitoneal administration of PARP inhibitors, benzamide or 3-amino benzamide, after I/R injury accelerates the recovery of normal renal function, as assessed by monitoring the levels of plasma creatinine and blood urea nitrogen during 6 days postischemia.	Nitrogen	224-232	poly (ADP-ribose) polymerase 1	Rattus norvegicus	34-38
11012666-6	2000	The full-length DPP8 cDNA codes for an 882-amino-acid protein that has about 27% identity and 51% similarity to DPPIV and FAP, but no transmembrane domain and no N-linked or O-linked glycosylation.	Nitrogen	23-24	dipeptidyl peptidase 4	Homo sapiens	112-117
10989127-9	2000	A potential N-glycosylation site (site 1) with similar tripeptide patterns was observed at the same position in human plasma (HYAL1), human lysosomes (HYAL2) and in two newly reported hyaluronidases (HYAL4 and HYALP1).	Nitrogen	12-13	hyaluronidase 2	Homo sapiens	151-156
10989127-9	2000	A potential N-glycosylation site (site 1) with similar tripeptide patterns was observed at the same position in human plasma (HYAL1), human lysosomes (HYAL2) and in two newly reported hyaluronidases (HYAL4 and HYALP1).	Nitrogen	12-13	hyaluronidase 4	Homo sapiens	200-205
11007268-0	2000	Selective and facile cyclization of N-chloroacetylated peptides from the C4 domain of HIV Gp120 in LiCl/DMF solvent systems.	Nitrogen	36-37	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	90-95
9814988-2	1998	Replacement of five arginines with N (5R/N) or T residues in the initial COOH-terminal domain (CT1) of Cx32 enhanced CO2 sensitivity.	Nitrogen	35-36	gap junction protein beta 1 L homeolog	Xenopus laevis	103-107
9814988-2	1998	Replacement of five arginines with N (5R/N) or T residues in the initial COOH-terminal domain (CT1) of Cx32 enhanced CO2 sensitivity.	Nitrogen	41-42	gap junction protein beta 1 L homeolog	Xenopus laevis	103-107
9791119-1	1998	GATA family proteins Gln3p, Gat1p, Dal80p, and Deh1p mediate the regulation of nitrogen catabolite repression (NCR)-sensitive gene expression in Saccharomyces cerevisiae.	Nitrogen	79-87	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	21-26
33674271-4	2021	The N-oxidation of PQ to PN1 was mainly mediated by CYP3A4, and PN1 can rapidly reduce back to PQ via CYP/FMO enzymes.	Nitrogen	4-5	peptidylprolyl isomerase G	Homo sapiens	52-55
11026737-4	2000	At 10 microM PER, a concentration consistent with anticipated in vivo liver concentrations, CYP3A4 and CYP2C9 contributed 50% and 35%, respectively, to PER-N-demethylation.	Nitrogen	156-157	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	103-109
33674271-5	2021	In accordance with these findings, the CYP non-selective inhibitor (1-ABT) or CYP3A4 inhibitor (ketoconazole) inhibited the N-oxidation pathway in liver microsomes (>90%), and the reduction metabolism was inhibited by 1-ABT (>90%) or methimazole (~50%).	Nitrogen	124-125	peptidylprolyl isomerase G	Homo sapiens	39-42
33933451-3	2021	Here we characterized the role of N-glycosylation in limiting PMP22 trafficking.	Nitrogen	34-35	peripheral myelin protein 22	Homo sapiens	62-67
10972224-8	2000	Pig CD29 deduced amino acid sequence displays extensive conservation compared with CD29 sequences from other species and a common structural feature with all the other CD29 molecules analyzed in mammals, including the 12 potential N-glycosilation sites.	Nitrogen	231-232	integrin subunit beta 1	Sus scrofa	4-8
9786864-4	1998	The extracellular domain of human leptin receptor was expressed in and purified from Chinese hamster ovary cells and was found to contain extensive N-glycosylation (approximately 36% of the total protein).	Nitrogen	148-149	leptin receptor	Homo sapiens	34-49
33933451-4	2021	We first eliminated N-glycosylation using an N41Q mutation, which resulted in an almost 3-fold increase in trafficking efficiency of wild type (WT) PMP22 and a 10-fold increase for the severely unstable L16P disease mutant in HEK293 cells, with similar results in Schwann cells.	Nitrogen	20-21	peripheral myelin protein 22	Homo sapiens	148-153
9778359-0	1998	N-Linked glycosylation is essential for the functional expression of the recombinant P2X2 receptor.	Nitrogen	0-1	purinergic receptor P2X 2	Homo sapiens	85-89
33933451-9	2021	This work shows that N-glycosylation is a limiting factor to forward trafficking PMP22 and sheds light on the proteins involved in its quality control.	Nitrogen	21-22	peripheral myelin protein 22	Homo sapiens	81-86
9778359-6	1998	In this study, we focused on the consequences of removing N-linked glycosylation from the P2X2 receptor by using two different approaches, tunicamycin treatment or site-directed mutagenesis.	Nitrogen	58-59	purinergic receptor P2X 2	Homo sapiens	90-94
9778359-8	1998	In addition, loss of function was observed with the elimination of all three N-linked glycosylation sites from P2X2.	Nitrogen	77-78	purinergic receptor P2X 2	Homo sapiens	111-115
10993349-2	2000	Preparation of various N,N"-disubstituted ureas from aliphatic primary amines, RNH2 (R = n-Pr, n-Bu, i-Pr, sec-Bu, or t-Bu), was achieved in good to excellent yields.	Nitrogen	10-11	NLR family pyrin domain containing 4	Homo sapiens	79-83
33981677-3	2021	In the workflow of global N-glycosylation analysis, enzymatic digestion is the main rate-limiting step, and it includes both protease digestion and peptide-N4-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNGase) F deglycosylation.	Nitrogen	26-27	N-glycanase 1	Homo sapiens	148-206
10901693-3	2000	Two UDP-glucuronosyltransferases (UGTs) present in human liver, UGT1A4 and UGT1A3, were previously shown to catalyze tertiary amine N-glucuronidation when expressed in HK293 cells.	Nitrogen	132-133	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	64-70
10901693-5	2000	When homogenates of HK293 cells expressing UGT1A4 were incubated without detergent, N-glucuronidation kinetics were monophasic with K(M) values of 59 +/- 5 microM for (R)- and 86 +/- 26 microM for (S)-ketotifen.	Nitrogen	84-85	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	43-49
10901693-8	2000	With amitriptyline as the substrate, N-glucuronidation kinetics in the absence of detergent were biphasic in human liver microsomes and monophasic with a high K(M) value in cell homogenates containing UGT1A4.	Nitrogen	37-38	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	201-207
10901693-9	2000	The results suggest that UGT1A4 and UGT1A3 catalyze high-K(M) N-glucuronidation of tertiary amine drugs, whereas the low-K(M) reaction requires either an alternative enzyme or a special conformation of UGT1A4 or UGT1A3 that can be attained in liver microsomes, but not in HK293 cell membranes.	Nitrogen	62-63	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	25-31
10901693-9	2000	The results suggest that UGT1A4 and UGT1A3 catalyze high-K(M) N-glucuronidation of tertiary amine drugs, whereas the low-K(M) reaction requires either an alternative enzyme or a special conformation of UGT1A4 or UGT1A3 that can be attained in liver microsomes, but not in HK293 cell membranes.	Nitrogen	62-63	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	202-208
10920257-10	2000	The largest factor in the substantially low pK(a) of reduced flavin in DAO is probably the steric hindrance between the hydrogen atom of H-N(1)(flavin) and the hydrogen atom of H-N of Gly315, which becomes significant when a hydrogen is bound to N(1) of flavin.	Nitrogen	139-140	D-amino acid oxidase	Homo sapiens	71-74
9756538-2	1998	Administration of insulin-like growth factor I (IGF-I) has a nitrogen-sparing effect after burn injury, but the influence of this treatment on protein turnover rates in skeletal muscle is not known.	Nitrogen	61-69	insulin-like growth factor 1	Rattus norvegicus	18-46
9756538-2	1998	Administration of insulin-like growth factor I (IGF-I) has a nitrogen-sparing effect after burn injury, but the influence of this treatment on protein turnover rates in skeletal muscle is not known.	Nitrogen	61-69	insulin-like growth factor 1	Rattus norvegicus	48-53
33981677-3	2021	In the workflow of global N-glycosylation analysis, enzymatic digestion is the main rate-limiting step, and it includes both protease digestion and peptide-N4-(N-acetyl-beta-glucosaminyl) asparagine amidase (PNGase) F deglycosylation.	Nitrogen	26-27	N-glycanase 1	Homo sapiens	208-214
9877101-9	1998	By using 3H-glucosamine as a marker of N-glycosylation, its incorporation into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors, and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	39-40	tyrosinase	Mus musculus	79-89
9877101-9	1998	By using 3H-glucosamine as a marker of N-glycosylation, its incorporation into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors, and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	152-153	tyrosinase	Mus musculus	79-89
9701597-12	1998	The results from this investigation demonstrate that GAD activity in leaves is altered by different nitrogen treatments, suggesting that GAD2 may play a unique role in nitrogen metabolism.	Nitrogen	100-108	glutamate decarboxylase	Arabidopsis thaliana	53-56
9701597-12	1998	The results from this investigation demonstrate that GAD activity in leaves is altered by different nitrogen treatments, suggesting that GAD2 may play a unique role in nitrogen metabolism.	Nitrogen	168-176	glutamate decarboxylase	Arabidopsis thaliana	53-56
10944147-0	2000	Short-term nitrogen-induced modulation of phosphoenolpyruvate carboxylase in tobacco and maize leaves.	Nitrogen	11-19	phosphoenolpyruvate carboxylase	Nicotiana tabacum	42-73
10944147-10	2000	It is concluded that PEPCase is sensitive to N metabolites which favour increased flow through the anapleurotic pathway in both C(3) and C(4) plants.	Nitrogen	45-46	phosphoenolpyruvate carboxylase	Nicotiana tabacum	21-28
10891485-0	2000	Shared roles of yeast glycogen synthase kinase 3 family members in nitrogen-responsive phosphorylation of meiotic regulator Ume6p.	Nitrogen	67-75	serine/threonine protein kinase RIM11	Saccharomyces cerevisiae S288C	22-48
10891485-7	2000	These findings argue that nitrogen limitation governs Rim11p/Mck1p-dependent phosphorylation of Ume6p, which in turn is required for Ume6p-Ime1p interaction and meiotic gene activation.	Nitrogen	26-34	serine/threonine protein kinase RIM11	Saccharomyces cerevisiae S288C	54-60
10861210-1	2000	The human erythrocyte anion exchanger (AE)1 (Band 3) contains a single complex N-linked oligosaccharide that is attached to Asn(642) in the fourth extracellular loop of this polytopic membrane protein, while other isoforms (AE2, AE3 and trout AE1) are N-glycosylated on the preceding extracellular loop.	Nitrogen	79-80	solute carrier family 4 member 2	Homo sapiens	224-227
10809695-0	2000	In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex.	Nitrogen	107-115	arginase	Saccharomyces cerevisiae S288C	68-72
9642163-8	1998	N-terminal sequence analysis identified the proteins as ribophorin I, ribophorin II (doublet), and a 50-kDa homologue of Wbp1, a yeast protein essential for N-glycosylation.	Nitrogen	0-1	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	121-125
10809695-0	2000	In Saccharomyces cerevisiae, expression of arginine catabolic genes CAR1 and CAR2 in response to exogenous nitrogen availability is mediated by the Ume6 (CargRI)-Sin3 (CargRII)-Rpd3 (CargRIII) complex.	Nitrogen	107-115	ornithine-oxo-acid transaminase	Saccharomyces cerevisiae S288C	77-81
33891343-0	2021	One-Step Template/Solvent-Free Pyrolysis for in-situ  Immobilization of CoP Nanoparticles onto N and P co-Doped Carbon Porous Nanosheets towards High-efficiency Electrocatalytic Hydrogen Evolution.	Nitrogen	76-77	caspase recruitment domain family member 16	Homo sapiens	72-75
10809695-6	2000	This histone deacetylase complex prevents the synthesis of the two arginine catabolic enzymes, arginase (CAR1) and ornithine transaminase (CAR2), as long as exogenous nitrogen is available.	Nitrogen	167-175	arginase	Saccharomyces cerevisiae S288C	105-109
10809695-6	2000	This histone deacetylase complex prevents the synthesis of the two arginine catabolic enzymes, arginase (CAR1) and ornithine transaminase (CAR2), as long as exogenous nitrogen is available.	Nitrogen	167-175	ornithine-oxo-acid transaminase	Saccharomyces cerevisiae S288C	139-143
10809695-7	2000	Upon nitrogen depletion, repression at URS1 is released and Ume6 interacts with ArgRI and ArgRII, two proteins involved in arginine-dependent activation of CAR1 and CAR2, leading to high levels of the two catabolic enzymes despite a low cytosolic arginine pool.	Nitrogen	5-13	arginase	Saccharomyces cerevisiae S288C	156-160
10809695-7	2000	Upon nitrogen depletion, repression at URS1 is released and Ume6 interacts with ArgRI and ArgRII, two proteins involved in arginine-dependent activation of CAR1 and CAR2, leading to high levels of the two catabolic enzymes despite a low cytosolic arginine pool.	Nitrogen	5-13	ornithine-oxo-acid transaminase	Saccharomyces cerevisiae S288C	165-169
9662428-1	1998	We examined cytokinin and nitrate responsiveness in gene expression of five distinct response regulator homologs (ARR3-ARR7) in the leaves of nitrogen-starved Arabidopsis plants.	Nitrogen	142-150	response regulator 7	Arabidopsis thaliana	119-123
9680059-2	1998	In order to improve the quality of the NMR data, Leu-enkephalin was synthesized with 15N-labelled uniformly on all amide nitrogens and examined in a viscous solvent medium at low temperature.	Nitrogen	121-130	prodynorphin	Homo sapiens	49-63
33876698-10	2021	N-glycosylated forms of PPT1 were elaborated.	Nitrogen	0-1	palmitoyl-protein thioesterase 1	Homo sapiens	24-28
9692515-5	1998	There was evidence of an increase in mPAP, MDA, PAF and ET-1 in the plasma, and activity of PLA2, PAF and ET-1 of the lung tissues when the rats inhaled a 10% mixture of oxygen in nitrogen.	Nitrogen	180-188	phospholipase A2 group IB	Rattus norvegicus	92-96
10814226-0	2000	One-Pot synthesis of N-protected amino trifluoromethyl ketones as hydrated hydrochloride salts via the CsF-catalyzed reactions of (Trifluoromethyl)trimethylsilane with N-protected amino esters	Nitrogen	21-22	colony stimulating factor 2	Homo sapiens	103-106
33859256-6	2021	Because tPA is a glycoprotein with three N-linked glycosylation sites, we hypothesized that tPA contains mannose 6-phosphate (M6P) and binds CI-MPR in a M6P-dependent manner.	Nitrogen	41-42	insulin like growth factor 2 receptor	Homo sapiens	141-147
10785812-4	2000	When N2 is used as the inert gas in the synthesis of the starting material [N(CH2CH2NNp)3WCl] [Np = CH2C-(CH3)3], the complex [[N(CH2CH2NNp)3]W2(mu, eta 1: eta 1-N2)] (4) is formed as a side product.	Nitrogen	5-7	secreted phosphoprotein 1	Homo sapiens	149-154
10785812-4	2000	When N2 is used as the inert gas in the synthesis of the starting material [N(CH2CH2NNp)3WCl] [Np = CH2C-(CH3)3], the complex [[N(CH2CH2NNp)3]W2(mu, eta 1: eta 1-N2)] (4) is formed as a side product.	Nitrogen	5-7	secreted phosphoprotein 1	Homo sapiens	156-161
9581821-2	1998	They undergo activation via N-hydroxylation by cytochrome P450 1A2 (CYP1A2), followed by O-esterification by O-acetyltransferase (OAT).	Nitrogen	28-29	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	68-74
10745000-2	2000	Fungal GATA factors regulate nitrogen metabolism, light induction, siderophore biosynthesis and mating-type switching.	Nitrogen	29-37	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	7-11
33928100-7	2021	The results showed that EPO significantly decreased serum creatinine, blood urea nitrogen, and cystatin C levels and alleviated renal histological changes in vivo.	Nitrogen	81-89	erythropoietin	Mus musculus	24-27
10692464-7	2000	Taken together, N-linked glycosylation appears to play key roles in the cell-surface expression and ligand binding of LOX-1.	Nitrogen	16-17	oxidized low density lipoprotein receptor 1	Bos taurus	118-123
9580643-2	1998	In 3-hr tests of free-feeding (satiated) rats, intra-ACB administration of the mu receptor agonist D-Ala2,N,Me-Phe4, Gly-ol5-enkephalin (DAMGO; 0, 0.025, 0.25 and 2.5 micrograms bilaterally) markedly enhanced the intake of fat or carbohydrate when the diets were presented individually (although the effect on fat intake was much greater in magnitude).	Nitrogen	106-107	proenkephalin	Rattus norvegicus	125-135
9576798-10	1998	The coordination of N and C metabolism is retained during drought conditions via modulation of the activities of Suc phosphate synthase and NR commensurate with the prevailing rate of photosynthesis.	Nitrogen	3-4	nitrate reductase [NADH] 1	Zea mays	141-143
9537389-6	1998	In addition, ags1delta strains underglycosylated invertase but had normal carboxypeptidase Y glycosylation, suggesting that Ags1p is required for the elaboration of outer N-glycosyl chains.	Nitrogen	171-172	ubiquitin-binding ESCRT-I subunit protein STP22	Saccharomyces cerevisiae S288C	124-129
9542130-3	1998	Edman degradation of the intact protein and nine peptides, derived by proteolytic digestion of the A33 antigen with Asp-N endoproteinase, thermolysin, trypsin and pepsin followed by micropreparative reversed-phase high-performance liquid chromatography, allowed the unambiguous sequence assignment of 153 amino acid residues; these data reveal one N-glycosylation sequeon in Asp-N endoproteinase peptide D4, and a disulfide linkage between peptides D1 and D4.	Nitrogen	120-121	glycoprotein A33	Homo sapiens	99-102
10741417-1	2000	We present the entire sequence of the mouse Fat orthologue (mFat1), a protein of 4,588 amino acids with 34 cadherin repeats, 27 potential N-glycosylation sites, five EGF repeats and a laminin A G-motif in its extracellular domain.	Nitrogen	138-139	CD36 molecule	Mus musculus	44-47
10712595-5	2000	The existence of only three N-linked side chains is evidenced by the sequential removal of three carbohydrate chains from salmon antithrombin during timed-digestion with N-glycosidase F. The high heparin binding affinity of the salmon inhibitor, Kd of 2.2 and 48 nM at I = 0.15 and 0.3, respectively, is very similar to that of the minor human isoform beta-antithrombin, which is not glycosylated at Asn135.	Nitrogen	28-29	serpin family C member 1	Homo sapiens	129-141
10712595-5	2000	The existence of only three N-linked side chains is evidenced by the sequential removal of three carbohydrate chains from salmon antithrombin during timed-digestion with N-glycosidase F. The high heparin binding affinity of the salmon inhibitor, Kd of 2.2 and 48 nM at I = 0.15 and 0.3, respectively, is very similar to that of the minor human isoform beta-antithrombin, which is not glycosylated at Asn135.	Nitrogen	28-29	serpin family C member 1	Homo sapiens	357-369
10353717-0	1998	Structural and functional consequences of an N-glycosylation mutation (HEMPAS) affecting human erythrocyte membrane glycoproteins.	Nitrogen	45-46	SEC23 homolog B, COPII coat complex component	Homo sapiens	71-77
33655750-3	2021	The structures of the gas-phase complexes were investigated by selective laser photodissociation of the diazirine chromophore at 354 nm, which resulted in a loss of N2 and formation of a transient carbene intermediate in the adrenaline ligand without causing its expulsion.	Nitrogen	165-167	gastrin	Homo sapiens	22-25
10695661-0	2000	Inhibition of MIP-1alpha-induced human neutrophil and monocyte chemotactic activity by reactive oxygen and nitrogen metabolites.	Nitrogen	107-115	C-C motif chemokine ligand 3	Homo sapiens	14-24
9405425-6	1997	N-Linked glycosylation of the FasL was not required for biological activity.	Nitrogen	0-1	Fas ligand	Homo sapiens	30-34
33168291-3	2021	It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2).	Nitrogen	401-409	complement C2	Homo sapiens	62-65
9405425-7	1997	However, the FasL expression level was dependent upon the three N-linked glycosylation sites.	Nitrogen	64-65	Fas ligand	Homo sapiens	13-17
33168291-3	2021	It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2).	Nitrogen	401-409	complement C2	Homo sapiens	221-224
10782279-0	2000	Novel practical synthesis of Kdn2en and its C-4 nitrogen-modified derivatives.	Nitrogen	48-56	complement C4A (Rodgers blood group)	Homo sapiens	44-47
33168291-3	2021	It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2).	Nitrogen	411-413	complement C2	Homo sapiens	62-65
33168291-3	2021	It was found that: (1) the efficiency of nitrate reduction by CO2- radical from the HCOOH/UV system was far lower than that of nitrite under the same reaction conditions, (2) the rate-control step of nitrate reduction by CO2- radical was the transformation process of nitrate into nitrite with an activation energy of 23.9 kcal/mol, (3) the final products of nitrate reduction were mainly composed of nitrogen (N2).	Nitrogen	411-413	complement C2	Homo sapiens	221-224
33168291-4	2021	On this basis, a novel strategy of rapid reduction of nitrate into N2 using CO2- radical was proposed.	Nitrogen	67-69	complement C2	Homo sapiens	76-79
9434174-4	1997	Sequence analysis revealed that HP-55 is produced as a precursor protein of 413 amino acids (aa), that it has a signal peptide of 24 aa, and that it contains four potential N-glycosylation sites.	Nitrogen	173-174	DNA polymerase gamma 2, accessory subunit	Homo sapiens	32-37
33168291-5	2021	Specifically, nitrate was firstly reduced into nitrite with the assistance of Zn/Ag bimetal, and then nitrite was further reduced into N2 by CO2- radical.	Nitrogen	135-137	complement C2	Homo sapiens	141-144
10634913-5	2000	It also affected the rate of degradation of the cytochrome b(6)f complex of the thylakoid membrane in two experimental situations: (1) during nitrogen starvation, and (2) in mutants deficient in the Rieske iron-sulfur protein.	Nitrogen	142-150	cytochrome b	Chlamydomonas reinhardtii	48-60
33168291-7	2021	This work provided a promising approach for the reduction of nitrate into nitrogen with high efficiency and high N2 selectivity by CO2- radical.	Nitrogen	74-82	complement C2	Homo sapiens	131-134
33168291-7	2021	This work provided a promising approach for the reduction of nitrate into nitrogen with high efficiency and high N2 selectivity by CO2- radical.	Nitrogen	113-115	complement C2	Homo sapiens	131-134
10652147-10	2000	Under nitrogen-limited conditions the phosphorylation was enhanced even though the level of PEPC protein was decreased.	Nitrogen	6-14	MLO-like protein 4	Zea mays	92-96
9389538-8	1997	Like rat d/tPRP, the mouse protein contains two putative N-linked glycosylation sites and six homologously located cysteine residues.	Nitrogen	57-58	prolactin family 8, subfamily A, member 2	Rattus norvegicus	9-15
33928602-7	2021	Additionally, a mutation was identified at an important N-glycosylation site; this mutation is believed to affect cathepsin B targeting inside the cell and make cathepsin B available in the extracellular environment.	Nitrogen	56-57	cathepsin B	Rattus norvegicus	114-125
9436095-6	1997	Nitrogen-linked glycosylation of native and murine synthesized bovine alpha-LA was identified by peptide-N-glycosidase F treatment, and the N-terminal amino acid sequence of HPLC-purified bovine alpha-LA from mouse milk was confirmed to be identical to native bovine alpha-LA.	Nitrogen	0-8	lactalbumin alpha	Bos taurus	70-78
9436095-6	1997	Nitrogen-linked glycosylation of native and murine synthesized bovine alpha-LA was identified by peptide-N-glycosidase F treatment, and the N-terminal amino acid sequence of HPLC-purified bovine alpha-LA from mouse milk was confirmed to be identical to native bovine alpha-LA.	Nitrogen	0-8	lactalbumin alpha	Bos taurus	195-203
9436095-6	1997	Nitrogen-linked glycosylation of native and murine synthesized bovine alpha-LA was identified by peptide-N-glycosidase F treatment, and the N-terminal amino acid sequence of HPLC-purified bovine alpha-LA from mouse milk was confirmed to be identical to native bovine alpha-LA.	Nitrogen	0-8	lactalbumin alpha	Bos taurus	195-203
9483944-7	1997	Urinary excretion of urea nitrogen, Cr, Na, Cl, Pi and beta 2-microglobulin (beta 2-MG) were dependent upon the daily urine volume.	Nitrogen	26-34	beta-2-microglobulin	Homo sapiens	77-86
10585852-5	1999	We present here results on N-glycan processing of TRP-1 and tyrosinase and compare the maturation process and activity of both glycoproteins in the presence of inhibitors of the endoplasmic reticulum stages of N-glycosylation.	Nitrogen	27-28	tyrosinase	Mus musculus	60-70
10617575-4	1999	TOR inhibition by rapamycin induces expression of nitrogen source utilization genes controlled by the Ure2 repressor and the transcriptional regulator Gln3, and globally represses ribosomal protein expression.	Nitrogen	50-58	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	151-155
10601337-6	1999	Pulse-chase studies have shown that after delivery to the cell surface, newly synthesized AE1-4 is recycled to the Golgi where it acquires additional N-linked sugar modifications.	Nitrogen	150-151	solute carrier family 4 member 1 (Diego blood group)	Gallus gallus	90-95
10561578-0	1999	Role of N-glycosylation in cathepsin E.	Nitrogen	8-9	cathepsin E	Rattus norvegicus	27-38
33928602-7	2021	Additionally, a mutation was identified at an important N-glycosylation site; this mutation is believed to affect cathepsin B targeting inside the cell and make cathepsin B available in the extracellular environment.	Nitrogen	56-57	cathepsin B	Rattus norvegicus	161-172
10561578-2	1999	Cathepsin E (CE), a nonlysosomal, intracellular aspartic proteinase, exists in several molecular forms that are N-glycosylated with high-mannose and/or complex-type oligosaccharides.	Nitrogen	112-113	cathepsin E	Rattus norvegicus	0-11
10561578-2	1999	Cathepsin E (CE), a nonlysosomal, intracellular aspartic proteinase, exists in several molecular forms that are N-glycosylated with high-mannose and/or complex-type oligosaccharides.	Nitrogen	112-113	cathepsin E	Rattus norvegicus	13-15
33392644-6	2021	Inhibition of the N-glycosylation with tunicamycin caused a significant increase of NaV1.5 channel current (INa) when applied for 24 h. Tunicamycin shifted the steady-state inactivation curve to the hyperpolarization direction, whereas the activation curve was unaffected.	Nitrogen	18-19	sodium voltage-gated channel alpha subunit 5	Homo sapiens	84-90
10561578-3	1999	To investigate the role of N-glycosylation on the catalytic properties and molecular stability of CE, both natural and recombinant enzymes with distinct oligosaccharides were purified from different sources.	Nitrogen	27-28	cathepsin E	Rattus norvegicus	98-100
10561578-4	1999	An N-glycosylation minus mutant, that was constructed by site-directed mutagenesis (by changing asparagine residues to glutamine and aspartic acid residues at positions 73 and 305 in potential N-glycosylation sites of rat CE) and expressed in normal rat kidney cells, was also purified to homogeneity from the cell extracts.	Nitrogen	3-4	cathepsin E	Rattus norvegicus	222-224
10561578-11	1999	These results suggest that N-glycosylation in CE is important for the maintenance of its proper folding upon changes in temperature, pH and redox state, and that the complex-type oligosaccharides contribute to the completion of the tertiary structure to maintain its active conformation in the weakly acidic pH environments.	Nitrogen	27-28	cathepsin E	Rattus norvegicus	46-48
10579331-12	1999	The cysteine protease inhibitor N-acetyl-leucyl-leucyl-norleucinal, which inhibits SREBP degradation, enhanced the effect of SREBP-1a on the regulation of the rat HDL receptor SR-BI gene.	Nitrogen	32-33	scavenger receptor class B, member 1	Rattus norvegicus	176-181
9395215-2	1997	Mechanism studies indicate that I3C induces cytochromes P4501A1 and 1A2 (CYP1A1 and CYP1A2), isozymes that respectively metabolize IQ via ring hydroxylation or activate the carcinogen by N-hydroxylation.	Nitrogen	187-188	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	73-79
9391721-1	1997	The aim of this work was to clarify the role of urokinase-type plasminogen activator (uPA) on the profibrinolytic activity of heparin, chemically modified heparins [partially: N-desulfated (N-des), N-desulfated N-acetylated (N-des N-ac), O-desulfated (O-des), O/N-desulfated N-acetylated (O/N-des N-ac)] and heparan sulfate.	Nitrogen	176-177	plasminogen activator, urokinase	Mus musculus	48-84
9391721-1	1997	The aim of this work was to clarify the role of urokinase-type plasminogen activator (uPA) on the profibrinolytic activity of heparin, chemically modified heparins [partially: N-desulfated (N-des), N-desulfated N-acetylated (N-des N-ac), O-desulfated (O-des), O/N-desulfated N-acetylated (O/N-des N-ac)] and heparan sulfate.	Nitrogen	176-177	plasminogen activator, urokinase	Mus musculus	86-89
33392644-9	2021	These findings suggest that N-glycosylation disruption rescues the NaV1.5 channel possibly through the alteration of ubiquitin-proteasome activity, and changes gating properties of the NaV1.5 channel by modulating glycan milieu of the channel protein.	Nitrogen	28-29	sodium voltage-gated channel alpha subunit 5	Homo sapiens	67-73
33392644-9	2021	These findings suggest that N-glycosylation disruption rescues the NaV1.5 channel possibly through the alteration of ubiquitin-proteasome activity, and changes gating properties of the NaV1.5 channel by modulating glycan milieu of the channel protein.	Nitrogen	28-29	sodium voltage-gated channel alpha subunit 5	Homo sapiens	185-191
33876091-0	2021	Energy density of high-pressure nitrogen-rich MNx compounds.	Nitrogen	32-40	keratin 86	Homo sapiens	46-49
9379450-15	1997	The introduction of a methyl of phenyl group on the nitrogen of the pyrazolyl ring of 14b [see 14c, 14d, and 14e] also caused some loss of inhibition for P450(17 alpha).	Nitrogen	52-60	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	154-167
11900662-7	1999	(3) Plasma glutamic-pyruvic transaminase (GPT) and urea nitrogen levels in BPI group, though increasing, were obviously lower than those in PS group.	Nitrogen	56-64	bactericidal/permeability-increasing protein	Rattus norvegicus	75-78
10559172-1	1999	Dal82p binds to the UIS(ALL) sites of allophanate-induced genes of the allantoin-degradative pathway and functions synergistically with the GATA family Gln3p and Gat1p transcriptional activators that are responsible for nitrogen catabolite repression-sensitive gene expression.	Nitrogen	220-228	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	152-157
33876091-1	2021	In the past decade, a large number of nitrogen-rich MNx compounds have been discovered under high-pressure conditions.	Nitrogen	38-46	keratin 86	Homo sapiens	52-55
33876091-3	2021	The results show that the energy densities of MNx consisting of alkali metals and cyclo-N5- are less than ~0.5 TNT equivalence, whereas the group-III metal nitrides have high-energy density regardless of the type of nitrogen oligomers in the structures.	Nitrogen	216-224	keratin 86	Homo sapiens	46-49
10556788-0	1999	Regulation of circulating levels of IGF-I in pregnant rats: changes in nitrogen balance correspond with changes in serum IGF-I concentrations.	Nitrogen	71-79	insulin-like growth factor 1	Rattus norvegicus	36-41
10556788-0	1999	Regulation of circulating levels of IGF-I in pregnant rats: changes in nitrogen balance correspond with changes in serum IGF-I concentrations.	Nitrogen	71-79	insulin-like growth factor 1	Rattus norvegicus	121-126
10556788-10	1999	The mean difference in maternal nitrogen balance between pregnant and non-pregnant rats was positively correlated (r=0.87, P&lt;0.01) with the mean difference in maternal IGF-I concentrations, using linear regression analysis.	Nitrogen	32-40	insulin-like growth factor 1	Rattus norvegicus	171-176
10556788-11	1999	These results support the conclusion that the circulating concentration of IGF-I in pregnant rats is associated with the change in nitrogen balance, but not with circulating GH.	Nitrogen	131-139	insulin-like growth factor 1	Rattus norvegicus	75-80
9292005-4	1997	gp110 from all sources possessed a high-mannose type of N-glycosylation implying that gp110 has not passed through the Golgi.	Nitrogen	56-57	ADRM1 26S proteasome ubiquitin receptor	Homo sapiens	0-5
9291187-3	1997	The present studies determined whether N-glycosylation is necessary for the activity of NAD-dependent 11beta-HSD (11beta-HSD2).	Nitrogen	39-40	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	102-112
9291187-3	1997	The present studies determined whether N-glycosylation is necessary for the activity of NAD-dependent 11beta-HSD (11beta-HSD2).	Nitrogen	39-40	hydroxysteroid 11-beta dehydrogenase 2	Homo sapiens	114-125
33687628-3	2021	Nitrate reduction resulted in the production of nitrogen gas, while sulfate formed due to sulfide oxidation.	Nitrogen	48-56	gastrin	Homo sapiens	57-60
9244386-9	1997	N-linked structures on native BSSL were identified as mainly mono- and disialylated biantennary complex type structures with or without fucose substitution.	Nitrogen	0-1	carboxyl ester lipase	Homo sapiens	30-34
9274016-9	1997	Re-addition of nitrogen to cells starved for nitrogen in the presence of glucose failed to trigger activation of trehalase, caused strongly reduced and aberrant repression of CTT1 and SSA3, and failed to induce the upshift in RPL25 expression.	Nitrogen	15-23	Hsp70 family ATPase SSA3	Saccharomyces cerevisiae S288C	184-188
10537291-2	1999	Cytochrome P4501A2 (CYP1A2)-mediated N-hydroxylation followed by phase II O-esterification by N-acetyltransferase (NAT2) are generally regarded as activation processes in which MeIQx and other HAAs are converted to genotoxic species.	Nitrogen	37-38	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	0-18
10537291-2	1999	Cytochrome P4501A2 (CYP1A2)-mediated N-hydroxylation followed by phase II O-esterification by N-acetyltransferase (NAT2) are generally regarded as activation processes in which MeIQx and other HAAs are converted to genotoxic species.	Nitrogen	37-38	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	20-26
10506112-7	1999	UGT1A4 N-glucuronidated N"-hydroxy- N-acetylbenzidine at the highest relative rate compared with the other transferases.	Nitrogen	7-8	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	0-6
33606934-3	2021	It is widely accepted that the protonation in the gas phase takes place primarily on the carbonyl oxygen atom when the sample is sprayed in methanol and on the nitrogen atom when acetonitrile is used as the spray solvent.	Nitrogen	160-168	gastrin	Homo sapiens	50-53
10511541-0	1999	Mks1p is a regulator of nitrogen catabolism upstream of Ure2p in Saccharomyces cerevisiae.	Nitrogen	24-32	Mks1p	Saccharomyces cerevisiae S288C	0-5
10511541-2	1999	Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation.	Nitrogen	61-69	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	95-100
10511541-2	1999	Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation.	Nitrogen	61-69	allantoate permease	Saccharomyces cerevisiae S288C	126-130
10511541-2	1999	Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation.	Nitrogen	151-159	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	95-100
10511541-2	1999	Ure2p of Saccharomyces cerevisiae is a negative regulator of nitrogen catabolism that inhibits Gln3p, a positive regulator of DAL5, and other genes of nitrogen assimilation.	Nitrogen	151-159	allantoate permease	Saccharomyces cerevisiae S288C	126-130
9237632-1	1997	We have isolated two Arabidopsis thaliana cDNAs by complementation of a yeast gln3 gdh1 strain that is affected in the regulation of nitrogen metabolism.	Nitrogen	133-141	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	78-82
9237632-1	1997	We have isolated two Arabidopsis thaliana cDNAs by complementation of a yeast gln3 gdh1 strain that is affected in the regulation of nitrogen metabolism.	Nitrogen	133-141	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	83-87
9193097-7	1997	In the 5" flanking region of the gene for Fd VI only, we identified NIT-2 motifs, which are widely found in genes for enzymes related to nitrogen metabolism.	Nitrogen	137-145	ferredoxin-6, chloroplastic	Zea mays	42-47
10511541-3	1999	Dal5p, the allantoate permease, allows ureidosuccinate uptake (Usa(+)) when cells grow on a poor nitrogen source such as proline.	Nitrogen	97-105	allantoate permease	Saccharomyces cerevisiae S288C	0-5
33657546-1	2021	Systematic analysis of the surface morphology, crystalline phase, chemical composition and elemental distribution along depth for nitrogen-doped niobium was carried out through different ways of characterization, including SEM, AFM, GIXRD, RBS and layer-by-layer XPS analysis.	Nitrogen	130-138	establishment of sister chromatid cohesion N-acetyltransferase 2	Homo sapiens	240-243
10482615-3	1999	Easily detected by fluorescence microscopy and immunoblot analysis with anti-GFP antibodies, the mCAT1-GFP fusion protein was expressed in an N-glycosylated form on the cell surface and in the Golgi apparatus, retaining the ecotropic receptor function.	Nitrogen	142-143	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	97-102
9163700-9	1997	Cytosols showed high activity for N-acetylation of p-aminobenzoic acid, but not of sulfamethazine, indicating that acetyltransferase-1 (NAT1) is predominantly expressed in this tissue.	Nitrogen	34-35	N-acetyltransferase 1	Homo sapiens	136-140
33854899-0	2021	Ultrafine MoP Nanoparticle Splotched Nitrogen-Doped Carbon Nanosheets Enabling High-Performance 3D-Printed Potassium-Ion Hybrid Capacitors.	Nitrogen	37-45	opioid receptor mu 1	Homo sapiens	10-13
9168895-5	1997	However, the G445A (Val149--&gt;Ile) substitution yielded expression of recombinant NAT1 protein that catalyzed the N-acetylation of aromatic amines and the O- and N,O-acetylation of their N-hydroxylated metabolites at rates up to 2-fold higher than wild-type recombinant human NAT1.	Nitrogen	84-85	N-acetyltransferase 1	Homo sapiens	278-282
9168895-5	1997	However, the G445A (Val149--&gt;Ile) substitution yielded expression of recombinant NAT1 protein that catalyzed the N-acetylation of aromatic amines and the O- and N,O-acetylation of their N-hydroxylated metabolites at rates up to 2-fold higher than wild-type recombinant human NAT1.	Nitrogen	116-117	N-acetyltransferase 1	Homo sapiens	84-88
10512881-0	1999	The EF-hand Ca(2+)-binding protein p22 associates with microtubules in an N-myristoylation-dependent manner.	Nitrogen	74-75	calcineurin like EF-hand protein 1	Homo sapiens	35-38
10512881-2	1999	Here we focus on p22, an N-myristoylated, widely expressed EF-hand Ca(2+)-binding protein conserved throughout evolution, which was shown previously to be required for membrane traffic.	Nitrogen	25-26	calcineurin like EF-hand protein 1	Homo sapiens	17-20
10512881-6	1999	Our results indicate that p22 associates with microtubules via a novel N-myristoylation-dependent mechanism that does not involve classic microtubule-associated proteins and motor proteins.	Nitrogen	71-72	calcineurin like EF-hand protein 1	Homo sapiens	26-29
10512881-7	1999	The association of p22 with microtubules requires the N-myristoylation of p22 but does not involve p22"s Ca(2+)-binding activity, suggesting that the p22-microtubule association and the role of p22 in membrane traffic are functionally related, because N-myristoylation is required for both events.	Nitrogen	54-55	calcineurin like EF-hand protein 1	Homo sapiens	19-22
10512881-7	1999	The association of p22 with microtubules requires the N-myristoylation of p22 but does not involve p22"s Ca(2+)-binding activity, suggesting that the p22-microtubule association and the role of p22 in membrane traffic are functionally related, because N-myristoylation is required for both events.	Nitrogen	54-55	calcineurin like EF-hand protein 1	Homo sapiens	74-77
10512881-7	1999	The association of p22 with microtubules requires the N-myristoylation of p22 but does not involve p22"s Ca(2+)-binding activity, suggesting that the p22-microtubule association and the role of p22 in membrane traffic are functionally related, because N-myristoylation is required for both events.	Nitrogen	54-55	calcineurin like EF-hand protein 1	Homo sapiens	74-77
10512881-7	1999	The association of p22 with microtubules requires the N-myristoylation of p22 but does not involve p22"s Ca(2+)-binding activity, suggesting that the p22-microtubule association and the role of p22 in membrane traffic are functionally related, because N-myristoylation is required for both events.	Nitrogen	54-55	calcineurin like EF-hand protein 1	Homo sapiens	74-77
10512881-7	1999	The association of p22 with microtubules requires the N-myristoylation of p22 but does not involve p22"s Ca(2+)-binding activity, suggesting that the p22-microtubule association and the role of p22 in membrane traffic are functionally related, because N-myristoylation is required for both events.	Nitrogen	54-55	calcineurin like EF-hand protein 1	Homo sapiens	74-77
10512881-7	1999	The association of p22 with microtubules requires the N-myristoylation of p22 but does not involve p22"s Ca(2+)-binding activity, suggesting that the p22-microtubule association and the role of p22 in membrane traffic are functionally related, because N-myristoylation is required for both events.	Nitrogen	252-253	calcineurin like EF-hand protein 1	Homo sapiens	19-22
10504238-6	1999	One set is assigned to the remote (N1) nitrogen in the dimethylbenzimidazole alpha-axial ligand by using two independent approaches: (a) comparison of ESEEM from cob(II)alamin with ESEEM from cob(II)inamide-ligand model compounds and (b) from the correspondence between the N1 (14)N nuclear quadrupole parameters derived from ESEEM simulations and those computed by using density functional theory.	Nitrogen	39-47	metabolism of cobalamin associated B	Homo sapiens	162-165
9139847-8	1997	Our findings suggest that tumor cytostasis of neutrophils activated by rIFN-gamma is mediated by L-arginine-derived nitrogen oxidation products, and that O(2)- produced by these neutrophils reduces NO-mediated tumor cytostasis at low NO concentrations.	Nitrogen	116-124	interferon gamma	Rattus norvegicus	71-81
9096605-8	1997	Serum IGF-I increased stepwise from placebo (699 +/- 40 to 1,579 +/- 96 micrograms/L in the combined GH/IGF-I group), and was correlated negatively with the capacity of urea-nitrogen synthesis (P &lt; .01).	Nitrogen	174-182	insulin-like growth factor 1	Rattus norvegicus	6-11
9096605-8	1997	Serum IGF-I increased stepwise from placebo (699 +/- 40 to 1,579 +/- 96 micrograms/L in the combined GH/IGF-I group), and was correlated negatively with the capacity of urea-nitrogen synthesis (P &lt; .01).	Nitrogen	174-182	insulin-like growth factor 1	Rattus norvegicus	104-109
9096605-10	1997	Nitrogen contents of organs increased after both GH and IGF-I treatment, and even more so after the combination treatment, reaching an increase of 30% (P &lt; .05).	Nitrogen	0-8	insulin-like growth factor 1	Rattus norvegicus	56-61
33854899-2	2021	In this work, a series of MoP nanoparticle splotched nitrogen-doped carbon nanosheets (MoP@NC) is synthesized.	Nitrogen	53-61	opioid receptor mu 1	Homo sapiens	26-29
33854899-2	2021	In this work, a series of MoP nanoparticle splotched nitrogen-doped carbon nanosheets (MoP@NC) is synthesized.	Nitrogen	53-61	opioid receptor mu 1	Homo sapiens	87-90
33531535-0	2021	Gas-phase amination of aromatic hydrocarbons by corona discharge-assisted nitrogen fixation.	Nitrogen	74-82	gastrin	Homo sapiens	0-3
9088579-12	1997	CONCLUSIONS: In summary the theophylline 6 h plasma and 0-12 h urine ratios 1MU/13DMX and 3MX/13DMX, both reflecting N-demethylation seem to be predictors of the CYP1A2 mediated metabolism of theophylline, whereas only the plasma ratio correlated with the caffeine plasma 17DMX/13TMX ratio.	Nitrogen	2-3	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	162-168
9084457-1	1997	OBJECTIVE: To further substantiate the role of CYP1A2 and CYP3A4 for the N-demethylation in vivo.	Nitrogen	73-74	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	47-53
9084457-2	1997	At least three different P450s appear to be responsible for the N-demethylation of imipramine to desipramine in vivo: CYP1A2, CYP2C19, and CYP3A4.	Nitrogen	64-65	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	118-124
10484461-0	1999	Effects of reactive oxygen and nitrogen metabolites on MCP-1-induced monocyte chemotactic activity in vitro.	Nitrogen	31-39	C-C motif chemokine ligand 2	Homo sapiens	55-60
10455030-3	1999	To examine whether N-PH might instead mediate protein-protein interaction, a fusion protein with glutathione S-transferase (GST) expressing N-PH (GST-N-PH) was used to screen [(35)S]methionine metabolically labelled HL-60 and Bac1.	Nitrogen	140-141	glutathione S-transferase kappa 1	Homo sapiens	97-122
10510155-10	1999	CONCLUSIONS: The polymorphic enzyme CYP2C19 catalyses the high-affinity N-demethylation of sertraline, while CYP2C9 is one of the low-affinity components of this metabolic pathway.	Nitrogen	2-3	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	109-115
10510156-8	1999	Sulphaphenazole caused limited inhibition (&lt;30%) of both pathways in human liver microsomes and microsomes from cells transfected with CYP2C9 cDNA were able to mediate the metabolism of rosiglitazone, in particular the N-demethylation pathway, albeit at a much slower rate than CYP2C8.	Nitrogen	147-148	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	138-144
33531535-1	2021	This paper reports on the gas-phase amination reaction of aromatic hydrocarbons occurring under corona discharge conditions with N2 gas as the nitrogen source.	Nitrogen	129-131	gastrin	Homo sapiens	26-29
9065390-1	1997	In Chlamydomonas reinhardtii, the expression of the nit1 gene encoding nitrate reductase is dependent on the nature of the nitrogen source and on other environmental factors.	Nitrogen	123-131	uncharacterized protein	Chlamydomonas reinhardtii	52-56
9065390-1	1997	In Chlamydomonas reinhardtii, the expression of the nit1 gene encoding nitrate reductase is dependent on the nature of the nitrogen source and on other environmental factors.	Nitrogen	123-131	uncharacterized protein	Chlamydomonas reinhardtii	71-88
10514258-6	1999	In our recent report, various immunoblotting analyses have shown that the presence of a core N-glycosylation resident in the hIL-1beta fragment is likely to be of crucial importance in the high-level secretion of hG-CSF from the recombinant S. cerevisiae.	Nitrogen	93-94	colony stimulating factor 3	Homo sapiens	213-219
33531535-1	2021	This paper reports on the gas-phase amination reaction of aromatic hydrocarbons occurring under corona discharge conditions with N2 gas as the nitrogen source.	Nitrogen	129-131	gastrin	Homo sapiens	132-135
10514258-7	1999	When the N-glycosylation was completely blocked with the addition of tunicamycin to the culture, the secretion of hG-CSF and hGH was decreased to a negligible level although the other host-derived proteins were well secreted to the culture broth regardless of the presence of tunicamycin.	Nitrogen	9-10	colony stimulating factor 3	Homo sapiens	114-120
10469630-3	1999	In vitro metabolism studies with human and rat liver microsomes have shown that CYP1A2 is primarily responsible for catalyzing N-hydroxylation, the initial step in the metabolic activation of 4-ABP.	Nitrogen	127-128	amine oxidase, copper-containing 1	Mus musculus	194-197
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	41-47
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	61-67
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	94-100
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	105-111
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	105-111
9045801-9	1997	Derepression upon transfer to a poor nitrogen source is dependent upon GLN3.	Nitrogen	37-45	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	71-75
9057853-4	1997	Three structural features seem to be essential for antitumor activities: a positive charge density at carbon C-7, a side chain at position C-2 or C-9 of the thiazoloquinoline skeleton with two basic nitrogens and a pKa value of 7.5-10 in the most basic center, and a conformational flexibility of this basic side chain.	Nitrogen	199-208	complement C2	Homo sapiens	139-142
9065690-1	1997	Expression of the catabolic gene encoding arginase in Saccharomyces cerevisiae, CAR1, is controlled by multiple nitrogen signals, such as the presence of the inducer, arginine, and the nature and amount of the nitrogen source.	Nitrogen	112-120	arginase	Saccharomyces cerevisiae S288C	80-84
9065690-1	1997	Expression of the catabolic gene encoding arginase in Saccharomyces cerevisiae, CAR1, is controlled by multiple nitrogen signals, such as the presence of the inducer, arginine, and the nature and amount of the nitrogen source.	Nitrogen	210-218	arginase	Saccharomyces cerevisiae S288C	80-84
9131945-9	1997	Microsomes from yeast cells expressing CYP2D6 and from human lymphoblastoid cells expressing CYP3A4 or CYP2C9-Arg N-demethylated AMI, but those from cells expressing CYPs 1A2 and 2C19 did not.	Nitrogen	114-115	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	103-109
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	94-100
33531535-1	2021	This paper reports on the gas-phase amination reaction of aromatic hydrocarbons occurring under corona discharge conditions with N2 gas as the nitrogen source.	Nitrogen	143-151	gastrin	Homo sapiens	26-29
33531535-1	2021	This paper reports on the gas-phase amination reaction of aromatic hydrocarbons occurring under corona discharge conditions with N2 gas as the nitrogen source.	Nitrogen	143-151	gastrin	Homo sapiens	132-135
33376510-8	2021	Overall, the study provides novel insights into the molecular mechanism by which GnT-V regulates the chemosensitivity to oxaliplatin, which involves the modulation of the drug transporter OCT2 by N-glycosylation in CRC cells.	Nitrogen	196-197	solute carrier family 22 member 2	Homo sapiens	188-192
10502094-4	1999	Using transgenic Arabidopsis thaliana [L.] Heynh., it was found that the promoter from the gene encoding the beta-subunit of beta-conglycinin up-regulates gene expression under sulfur deficiency and down-regulates gene expression under nitrogen deficiency.	Nitrogen	236-244	beta-conglycinin beta subunit 1	Glycine max	109-141
9111145-1	1997	Lectin mapping, carbohydrate analysis and electrospray mass spectrometry of boar seminal plasma PSP-II glycoforms show that its single N-glycosylation site displays a repertoire of carbohydrate structures consisting of the basic pentasaccharide core Man alpha 1-6[Man alpha 1-3]Man beta1-4GlcNAc beta1-4GlcNAc with a fucosyl residue alpha1-6-linked to the innermost N-acetylglucosamine residue.	Nitrogen	135-136	adrenoceptor alpha 1D	Homo sapiens	254-261
9111145-1	1997	Lectin mapping, carbohydrate analysis and electrospray mass spectrometry of boar seminal plasma PSP-II glycoforms show that its single N-glycosylation site displays a repertoire of carbohydrate structures consisting of the basic pentasaccharide core Man alpha 1-6[Man alpha 1-3]Man beta1-4GlcNAc beta1-4GlcNAc with a fucosyl residue alpha1-6-linked to the innermost N-acetylglucosamine residue.	Nitrogen	135-136	adrenoceptor alpha 1D	Homo sapiens	268-275
9111145-1	1997	Lectin mapping, carbohydrate analysis and electrospray mass spectrometry of boar seminal plasma PSP-II glycoforms show that its single N-glycosylation site displays a repertoire of carbohydrate structures consisting of the basic pentasaccharide core Man alpha 1-6[Man alpha 1-3]Man beta1-4GlcNAc beta1-4GlcNAc with a fucosyl residue alpha1-6-linked to the innermost N-acetylglucosamine residue.	Nitrogen	135-136	adrenoceptor alpha 1D	Homo sapiens	333-341
10497120-6	1999	Moreover, glycosylation also occurred when an N-glycosylation site was introduced into the second hydrophobic domain of the full-length A17L protein.	Nitrogen	46-47	IMV membrane protein	Vaccinia virus	136-140
33516905-12	2021	Serum analysis and proteomic profiling of hepatocytes from male CD73-LKO mice revealed significant metabolic imbalance, with elevated blood urea nitrogen (p<0.0001) and impairments in major metabolic pathways, including oxidative phosphorylation and AMP-activated protein kinase (AMPK) signaling.	Nitrogen	145-153	5' nucleotidase, ecto	Mus musculus	64-68
10409731-5	1999	Mutations in these genes cause the nitrogen-regulated general amino acid permease gene (GAP1) to be abnormally expressed and block the nonspecific induction of arginase (CAR1) and the peptide transporter (PTR2).	Nitrogen	35-43	arginase	Saccharomyces cerevisiae S288C	170-174
10505414-6	1999	The sequence analysis of two cDNA indicates open reading frames which show significant similarities to known proteins involved in mechanisms of regulation: 1) nifR3, an element of the nitrogen regulatory system in bacteria and 2) CROC-1, a newly identified human transcription factor.	Nitrogen	184-192	ubiquitin conjugating enzyme E2 V1	Homo sapiens	230-236
10477169-2	1999	A linear skeleton with a N-containing aromatic ring attached at C3 of the top A-ring, a central pyran B-ring and a six-membered bottom C-ring with no alkylation at C7 are required for the antitumor activities of the lead compounds, a 3-pyridyl benzopyran (code name H10) and its somewhat weaker 2-pyridyl regioisomer (code name H19).	Nitrogen	25-26	histocompatibility 10	Mus musculus	266-269
10340394-4	1999	When maintained in IL-3, about 3% of N-Fms cells formed large hemoglobinized colonies in semisolid cultures supplemented with erythropoietin (EPO).	Nitrogen	37-38	erythropoietin	Mus musculus	126-140
10340394-4	1999	When maintained in IL-3, about 3% of N-Fms cells formed large hemoglobinized colonies in semisolid cultures supplemented with erythropoietin (EPO).	Nitrogen	37-38	erythropoietin	Mus musculus	142-145
9343928-4	1997	Furthermore, we found that the introduction of a N-stearyl derivative of 3S-peptide-I in CHO/HIRc cells caused a significant increase in insulin-stimulated phosphorylation of the insulin receptor.	Nitrogen	49-50	insulin receptor	Cricetulus griseus	179-195
9063644-4	1997	The primary structure of the Mea-2 peptide, deduced from this nucleotide sequence, shows that it encode a 150 kDa protein, of 1325 amino acid residues, which contained five putative N-glycosylation sites and four leucine zipper motifs.	Nitrogen	182-183	golgi autoantigen, golgin subfamily a, 3	Mus musculus	29-34
9058209-10	1997	Furthermore, all these changes seemed to correlate with the presence of fatty liver and the high serum free fatty acid levels, suggesting that disturbance of fatty acid metabolism affects nitrogen metabolism at least in part via altered gene expression of transcription factors such as HNF-4, C/EBP-alpha, and C/EBP-beta.	Nitrogen	188-196	CCAAT/enhancer binding protein (C/EBP), beta	Mus musculus	310-320
8912512-3	1996	METHODS: TAP translocation of a panel of HLA-B27-binding peptides was measured with a labeled reporter peptide containing an N-linked glycosylation acceptor site in streptolysin O-permeabilized cells with different TAP alleles.	Nitrogen	125-126	major histocompatibility complex, class I, B	Homo sapiens	41-48
33508134-7	2021	Together with PHR1, several transcription factors that mediate the availability of other nutrients (such as nitrogen and zinc), light, and stress signals form an intricate transcriptional network to maintain P homeostasis under highly diverse environments.	Nitrogen	108-116	phosphate starvation response 1	Arabidopsis thaliana	14-18
21541594-6	1996	The T/N ratio of alpha 1AT bad a converse correlation with that of MMP7 (p=0.034).	Nitrogen	6-7	matrix metallopeptidase 7	Homo sapiens	67-71
10207060-2	1999	ARO9 expression is under the dual control of specific induction and nitrogen source regulation.	Nitrogen	68-76	aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	0-4
10207060-9	1999	Nitrogen regulation of ARO9 expression seems not directly to involve the general factor Ure2p, Gln3p, Nil1p, Uga43p, or Gzf3p.	Nitrogen	0-8	aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	23-27
10360417-4	1999	We suggest that N-linked sugar chains in PSA are altered during oncogenesis in the human prostate and may serve as diagnostic tools for PCA.	Nitrogen	16-17	kallikrein related peptidase 3	Homo sapiens	41-44
8895510-2	1996	Exposure of HeLa cells to camptothecin, etoposide or nitrogen mustard for 1 h in S phase resulted in delayed expression of cyclin B1 mRNA during the G2 arrest.	Nitrogen	53-61	cyclin B1	Homo sapiens	123-132
32947097-4	2021	Excellent performance of the CoP-NPC/GS was derived from scanty graphene (2 wt%)-driven compositional variation, which promotes the redox-active CoP phase and higher nitrogen content offering enhanced electronic conductivity.	Nitrogen	166-174	caspase recruitment domain family member 16	Homo sapiens	29-32
10328552-4	1999	The MBL binding to Colo205 cells was more strongly reduced by the pretreatment of the cells with an O-linked glycosylation inhibitor, benzyl-2-acetamide-2-deoxy-alpha-galactopyranoside (Bz-alpha-GalNAc), rather than an N-linked glycosylation inhibitor, tunicamycin.	Nitrogen	198-199	mannose binding lectin 2	Homo sapiens	4-7
8816501-1	1996	CAR1 (arginase) gene expression responds to multiple environmental signals; expression is induced in response to the intracellular accumulation of arginine and repressed when readily transported and catabolized nitrogen sources are available in the environment.	Nitrogen	211-219	arginase	Saccharomyces cerevisiae S288C	0-4
33350995-2	2021	CP 1 and CP 2 display new two-dimensional double-layered honeycomb frameworks containing uncoordinated nitrogen atoms from pyridine and tetrazole rings, which can easily form hydrogen bonds with various analytes.	Nitrogen	103-111	ceruloplasmin	Homo sapiens	9-13
8816501-7	1996	A single URS1 site mediates repression of CAR1 arginine-independent upstream activator site (UAS) activity in the absence of arginine and the presence of a poor nitrogen source (a condition under which the inducer-independent Gln3p can function in association with the UASNTR sites).	Nitrogen	161-169	arginase	Saccharomyces cerevisiae S288C	42-46
10219965-4	1999	Anti-CYP2C11 antibody inhibited the N-deethylation of S- and R-NS-21 in rat hepatic microsomes by 84 and 66% respectively, indicating that CYP2C11 is mainly responsible for these activities in male rats.	Nitrogen	36-37	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	5-12
10219965-4	1999	Anti-CYP2C11 antibody inhibited the N-deethylation of S- and R-NS-21 in rat hepatic microsomes by 84 and 66% respectively, indicating that CYP2C11 is mainly responsible for these activities in male rats.	Nitrogen	36-37	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	139-146
8824587-11	1996	atf1- and spc1- mutants are sensitive to osmotic stress and impaired for sexual development, showing that fission yeast uses a common pathway to respond to cytotoxic stress and nitrogen starvation.	Nitrogen	177-185	activating transcription factor 1	Homo sapiens	0-4
33436819-7	2021	The pure KCC-1 and KCC-1-NH2 are characterized using different evaluation methods such as FTIR, SEM, TEM and N2 adsorption analysis.	Nitrogen	109-111	solute carrier family 12 member 4	Homo sapiens	9-14
8884270-0	1996	A point mutation creating an extra N-glycosylation site in fibrillin-1 results in neonatal Marfan syndrome.	Nitrogen	35-36	fibrillin 1	Homo sapiens	59-70
9925876-0	1999	N-linked glycosylation sites determine HERG channel surface membrane expression.	Nitrogen	0-1	potassium voltage-gated channel subfamily H member 2	Homo sapiens	39-43
9925876-4	1999	While a recent report indicates that LQT in some patients is associated with a mutation of HERG at a consensus extracellular N-linked glycosylation site (N629), earlier studies failed to identify a role for N-linked glycosylation in the functional expression of voltage-gated K+ channels.	Nitrogen	125-126	potassium voltage-gated channel subfamily H member 2	Homo sapiens	91-95
9925876-4	1999	While a recent report indicates that LQT in some patients is associated with a mutation of HERG at a consensus extracellular N-linked glycosylation site (N629), earlier studies failed to identify a role for N-linked glycosylation in the functional expression of voltage-gated K+ channels.	Nitrogen	154-155	potassium voltage-gated channel subfamily H member 2	Homo sapiens	91-95
9925876-5	1999	In this study we used pharmacological agents and site-directed mutagenesis to assess the contribution of N-linked glycosylation to the surface localization of HERG channels.	Nitrogen	105-106	potassium voltage-gated channel subfamily H member 2	Homo sapiens	159-163
9925876-11	1999	Furthermore, patch clamp analysis revealed that there was a virtual absence of HERG current in the N-glycosylation mutants.	Nitrogen	99-100	potassium voltage-gated channel subfamily H member 2	Homo sapiens	79-83
9925876-13	1999	Taken together, these results strongly suggest that N-linked glycosylation is required for surface membrane expression of HERG.	Nitrogen	52-53	potassium voltage-gated channel subfamily H member 2	Homo sapiens	122-126
8808922-3	1996	The HYR1 gene sequence revealed a 937-codon open reading frame capable of encoding a protein with an N-terminal signal sequence, a C-terminal glycosylphosphatidylinositol-anchoring domain, 17 potential N glycosylation sites, and a large domain rich in serine and threonine (51% of 230 residues).	Nitrogen	101-102	peroxiredoxin HYR1	Saccharomyces cerevisiae S288C	4-8
8755910-0	1996	Interaction of the GATA factor Gln3p with the nitrogen regulator Ure2p in Saccharomyces cerevisiae.	Nitrogen	46-54	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	31-36
8776899-10	1996	Fusion genes for ERD5 and PUT1 complemented a put1 mutant of yeast, allowing put1 to grow with proline as the source of nitrogen.	Nitrogen	120-128	Methylenetetrahydrofolate reductase family protein	Arabidopsis thaliana	17-21
8663421-4	1996	SgIII was synthesized as a 61- or 63-kDa (N-glycosylated) protein and processed to a 48-kDa form which, in turn, was partially cleaved to fragments of 28 and 20 kDa.	Nitrogen	42-43	secretogranin III S homeolog	Xenopus laevis	0-5
9925876-14	1999	These findings may provide insight into a mechanism responsible for LQT2 due to N-linked glycosylation-related mutations of HERG.	Nitrogen	80-81	potassium voltage-gated channel subfamily H member 2	Homo sapiens	68-72
9925876-14	1999	These findings may provide insight into a mechanism responsible for LQT2 due to N-linked glycosylation-related mutations of HERG.	Nitrogen	80-81	potassium voltage-gated channel subfamily H member 2	Homo sapiens	124-128
9933620-3	1999	Neuropsin possesses an N-glycosylated "kallikrein loop" but forms six disulfide bonds corresponding to those of trypsin.	Nitrogen	0-1	kallikrein 1-related peptidase b9	Mus musculus	39-49
33413365-1	2021	Emerging evidence has revealed that the removal of N-linked glycosylation could enhance PD-L1 detection.	Nitrogen	51-52	CD274 molecule	Homo sapiens	88-93
9927660-6	1999	Furthermore, we show that a natural N-truncated isoform of NOVH produced by cells expressing the full-length NOVH protein also binds fibulin 1C with a high affinity, and we hypothesize that the production of truncated isoforms of NOVH (and probably of other CCN proteins) may be a critical aspect in the modulation of their biological activity.	Nitrogen	36-37	cellular communication network factor 3	Homo sapiens	59-63
9927660-6	1999	Furthermore, we show that a natural N-truncated isoform of NOVH produced by cells expressing the full-length NOVH protein also binds fibulin 1C with a high affinity, and we hypothesize that the production of truncated isoforms of NOVH (and probably of other CCN proteins) may be a critical aspect in the modulation of their biological activity.	Nitrogen	36-37	cellular communication network factor 3	Homo sapiens	109-113
9927660-6	1999	Furthermore, we show that a natural N-truncated isoform of NOVH produced by cells expressing the full-length NOVH protein also binds fibulin 1C with a high affinity, and we hypothesize that the production of truncated isoforms of NOVH (and probably of other CCN proteins) may be a critical aspect in the modulation of their biological activity.	Nitrogen	36-37	cellular communication network factor 3	Homo sapiens	109-113
8679611-9	1996	The different responses of the C14-C15 stretch mode to the Schiff base nitrogen deuteration in bovine and octopus pigments are due to the fact that the coupled C14-C15 stretch and the C12-C13 stretch motions in the model compound or in bovine rhodopsin are altered in octopus rhodopsin so that the stretch motion of the C14-15 bond is more localized, similar to the C-C stretch motion in the small Schiff base model compound.	Nitrogen	71-79	rhodopsin	Bos taurus	243-252
8679611-9	1996	The different responses of the C14-C15 stretch mode to the Schiff base nitrogen deuteration in bovine and octopus pigments are due to the fact that the coupled C14-C15 stretch and the C12-C13 stretch motions in the model compound or in bovine rhodopsin are altered in octopus rhodopsin so that the stretch motion of the C14-15 bond is more localized, similar to the C-C stretch motion in the small Schiff base model compound.	Nitrogen	71-79	rhodopsin	Bos taurus	276-285
8764331-7	1996	Among the recombinant human CYP isoforms, CYP2D6, 2B6, 3A4 and 1A2 catalyzed the 8-hydroxylation, and CYP1A2 and 3A4 were involved exclusively in the N-oxidation, whereas CYP2B6, 2C19, 1A2, 3A4 and 2D6 showed a catalytic activity for the N-demethylation, for either or both of MS enantiomers.	Nitrogen	150-151	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	102-108
9890748-2	1999	The open reading frame of 1,581 nt is predicted to encode a ZPB polypeptide of 527 amino acids which contains 20 cysteine residues, 7 potential N-linked glycosylation sites, a potential N-terminal signal peptide and a potential C-terminal trans-membrane domain, preceded by a furin proteolytic processing signal.	Nitrogen	144-145	zona pellucida glycoprotein 4 L homeolog	Xenopus laevis	60-63
33413365-4	2021	We found that removal of N-linked glycosylation markedly enhanced PD-L1 detection when the 28-8, CAL10 and SP142 monoclonal antibodies (mAbs) were used but slightly inhibited PD-L1 detection when the 73-10 mAb was used.	Nitrogen	25-26	CD274 molecule	Homo sapiens	66-71
33413365-4	2021	We found that removal of N-linked glycosylation markedly enhanced PD-L1 detection when the 28-8, CAL10 and SP142 monoclonal antibodies (mAbs) were used but slightly inhibited PD-L1 detection when the 73-10 mAb was used.	Nitrogen	25-26	CD274 molecule	Homo sapiens	175-180
8783260-8	1996	In the brain stem N-methyl-D-aspartate R1-4 was strongly expressed in various nuclei including the locus coeruleus, nucleus centralis superior and deep pontine nuclei.	Nitrogen	18-19	CD1b molecule	Homo sapiens	39-43
33430484-4	2021	Furthermore, the recent development of In(Ga)N nanostructure applications (light-emitting diodes, lasers, and gas sensors) is presented.	Nitrogen	45-46	gastrin	Homo sapiens	110-113
8663035-8	1996	The results indicate that the side chain of Asn101 and the backbone nitrogen of Gly102 function to stabilize a tetrahedral oxyanion resulting from attack of Cys1 on the glutamine carboxamide.	Nitrogen	68-76	cystin 1	Homo sapiens	157-161
10077186-6	1999	While this response to nitrogen starvation was likely mediated by the stress-responsive elements (STREs) in the promoter of these genes, we found that these elements were not responsible for the co-induction of genes involved in reserve carbohydrate metabolism during glucose limitation, since GLG1, which does not contain any STRE, was coordinately induced with GSY2 and TPS1.	Nitrogen	23-31	glycogenin glucosyltransferase GLG1	Saccharomyces cerevisiae S288C	294-298
10077186-6	1999	While this response to nitrogen starvation was likely mediated by the stress-responsive elements (STREs) in the promoter of these genes, we found that these elements were not responsible for the co-induction of genes involved in reserve carbohydrate metabolism during glucose limitation, since GLG1, which does not contain any STRE, was coordinately induced with GSY2 and TPS1.	Nitrogen	23-31	glycogen (starch) synthase GSY2	Saccharomyces cerevisiae S288C	363-367
10090557-4	1999	Molecular genetic studies showed a point mutation in the fibrillin 1 gene that creates a new N-glycosylation site, which has been described once before.	Nitrogen	93-94	fibrillin 1	Homo sapiens	57-68
33001558-0	2021	Predicting Nitrogen-based Families of Compounds: Transition-metal Guanidinates TCN3 (T = V, Nb, Ta) and Ortho-nitrido Carbonates T"2CN4 (T" = Ti, Zr, Hf).	Nitrogen	11-19	cobalamin binding intrinsic factor	Homo sapiens	79-83
9884409-6	1999	Sequencing of the mutant gC-1 gene revealed only one nucleotide change, resulting in replacement of Thr150 by an Ile, in turn destroying an N-glycosylation site at Asn148.	Nitrogen	140-141	solute carrier family 25 member 22	Homo sapiens	25-29
8665493-1	1996	The heterocyclic amines (HCAs) found in cooked meat are procarcinogens that are metabolically activated by N-hydroxylation followed by O-acetylation by the N-acetyltransferases NAT1 and NAT2.	Nitrogen	107-108	N-acetyltransferase 1	Homo sapiens	177-181
8643469-8	1996	The gdh1-1 mutant displays a conditional phenotype in that seedling growth is specifically retarded on media containing exogenously supplied inorganic nitrogen.	Nitrogen	151-159	glutamate dehydrogenase 1	Arabidopsis thaliana	4-10
8643469-9	1996	These results suggest that GDH1 plays a nonredundant role in ammonia assimilation under conditions of inorganic nitrogen excess.	Nitrogen	112-120	glutamate dehydrogenase 1	Arabidopsis thaliana	27-31
8622637-1	1996	The potent food mutagen/carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) undergoes metabolic N-hydroxylation by cytochromes P450, including cytochrome P450 1A2, followed by generation of an unstable ester catalyzed by acetyltransferases; promutagenic DNA adducts result.	Nitrogen	100-101	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	147-166
8636059-2	1996	This gene is not expressed in media containing glutamine, and its transcription is activated in response to Gln3p in cells using glutamate as the source of nitrogen and by Nil1p in cells using urea as the source of nitrogen.	Nitrogen	156-164	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	108-113
8636059-2	1996	This gene is not expressed in media containing glutamine, and its transcription is activated in response to Gln3p in cells using glutamate as the source of nitrogen and by Nil1p in cells using urea as the source of nitrogen.	Nitrogen	215-223	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	108-113
9864251-0	1999	Glucose 6-phosphate dehydrogenase is required for Salmonella typhimurium virulence and resistance to reactive oxygen and nitrogen intermediates.	Nitrogen	121-129	glucose-6-phosphate dehydrogenase 2	Mus musculus	0-33
9864251-1	1999	Salmonella typhimurium zwf mutants lacking glucose 6-phosphate dehydrogenase (G6PD) activity have increased susceptibility to reactive oxygen and nitrogen intermediates as well as attenuated virulence in mice.	Nitrogen	146-154	glucose-6-phosphate dehydrogenase 2	Mus musculus	43-76
9864251-1	1999	Salmonella typhimurium zwf mutants lacking glucose 6-phosphate dehydrogenase (G6PD) activity have increased susceptibility to reactive oxygen and nitrogen intermediates as well as attenuated virulence in mice.	Nitrogen	146-154	glucose-6-phosphate dehydrogenase 2	Mus musculus	78-82
10204246-4	1999	Traces of non-N-acetylated MT-2D and MT-2E were observed in a fifth, minor peak.	Nitrogen	14-15	metallothionein-2D	Oryctolagus cuniculus	27-32
8622686-4	1996	The demonstration that NCR-sensitive expression of multiple nitrogen-catabolic genes occurs in a gln3 delta ure2 delta dal80::hisG triple mutant indicated that the prevailing view of the nitrogen regulatory circuit was in need of revision; additional components clearly existed.	Nitrogen	60-68	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	97-101
8622686-4	1996	The demonstration that NCR-sensitive expression of multiple nitrogen-catabolic genes occurs in a gln3 delta ure2 delta dal80::hisG triple mutant indicated that the prevailing view of the nitrogen regulatory circuit was in need of revision; additional components clearly existed.	Nitrogen	187-195	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	97-101
32314265-0	2021	Nitrogen fixation estimates for the Baltic Sea indicate high rates for the previously overlooked Bothnian Sea.	Nitrogen	0-8	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	43-46
8631939-2	1996	Fusion proteins containing 82 or only 36 N-terminal residues of Mnt1p were produced and quantitatively N-glycosylated; glycosyl chains were shown to contain alpha1,6-, but not alpha1,3-mannose determinants, a structure typical for an early Golgi compartment.	Nitrogen	41-42	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	64-69
10195570-2	1999	Recently, AcSDKP has been shown to be a physiological substrate of the N-active site of angiotensin I-converting enzyme (ACE).	Nitrogen	71-72	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	88-119
10195570-2	1999	Recently, AcSDKP has been shown to be a physiological substrate of the N-active site of angiotensin I-converting enzyme (ACE).	Nitrogen	71-72	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	121-124
32314265-0	2021	Nitrogen fixation estimates for the Baltic Sea indicate high rates for the previously overlooked Bothnian Sea.	Nitrogen	0-8	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	106-109
32314265-3	2021	In the Bothnian Sea, estimated nitrogen fixation rates were 80 kt N year-1, which has doubled during recent decades and now exceeds external loading from rivers and atmospheric deposition of 69 kt year-1.	Nitrogen	31-39	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	16-19
9922157-11	1998	Finally, a comparison of cleavage site selection in the presence and absence of tunicamycin treatment showed that N-glycosylation of certain mutant forms of CSF-1(256) sterically interfered with protease accessibility, which in turn had an effect on the selection of the site used for cleavage.	Nitrogen	114-115	colony stimulating factor 1	Homo sapiens	157-162
8785485-5	1996	Treatment of these transduced cells with inhibitors of O-linked or N-linked protein glycosylation significantly inhibited E-selectin-mediated adhesion, though fluorescence-activated cell sorter analysis indicated no decrease in cell surface expression of SLeX, Slea or diSLeX.	Nitrogen	67-68	selectin E	Homo sapiens	122-132
33073996-2	2021	N-glycosylation of PD-L1 affects its interaction with PD-1, but little is known about the distribution of glycoforms at its four NXS/T sequons.	Nitrogen	0-1	CD274 molecule	Homo sapiens	19-24
8830251-2	1996	The Saccharomyces cerevisiae GCV2 gene, encoding the P-protein has been cloned by complementation of the gsd2 mutation which prevents cells converting glycine to serine or using glycine as the sole nitrogen source.	Nitrogen	198-206	glycine decarboxylase subunit P	Saccharomyces cerevisiae S288C	29-33
10985757-5	1998	In contrast, IGFBP-1 levels were high on admission, correlated with early changes in nitrogen balance, and fell rapidly during the first week.	Nitrogen	85-93	insulin like growth factor binding protein 1	Homo sapiens	13-20
32043277-1	2021	VERNALIZATION2 (VRN2), an angiosperm-specific subunit of the polycomb repressive complex 2 (PRC2), is an oxygen (O2 ) regulated target of the PCO branch of the PRT6 N-degron pathway of ubiquitin-mediated proteolysis.	Nitrogen	3-4	VEFS-Box of polycomb protein	Arabidopsis thaliana	16-20
9843412-7	1998	In CHO cells, a small portion of APP, principally the N-glycosylated isoform, formed complexes with PS1 in both ER- and Golgi-rich fractions, as detected by coimmunoprecipitation.	Nitrogen	54-55	presenilin 1	Mus musculus	100-103
9774483-7	1998	We then, using various N-glycosylation site mutants of NCAM, discovered that PST strongly prefer the sixth N-glycosylation site, which is the closest to the transmembrane domain, over the fifth site.	Nitrogen	23-24	neural cell adhesion molecule 1	Homo sapiens	55-59
9774483-8	1998	STX slightly prefer the sixth N-glycosylation site over the fifth N-glycosylation site.	Nitrogen	30-31	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	Homo sapiens	0-3
8573110-17	1996	From these results, we conclude that: (1) the process of lipid aggregation induced by SP-A cannot be correlated with that of self-association of the protein occurring at supramillimolar concentrations of Ca2+; and (2) the N-linked carbohydrate moiety of SP-A and the ability of SP-A to bind carbohydrates are not involved in lipid aggregation.	Nitrogen	222-223	pulmonary surfactant-associated protein A	Sus scrofa	254-258
8573110-17	1996	From these results, we conclude that: (1) the process of lipid aggregation induced by SP-A cannot be correlated with that of self-association of the protein occurring at supramillimolar concentrations of Ca2+; and (2) the N-linked carbohydrate moiety of SP-A and the ability of SP-A to bind carbohydrates are not involved in lipid aggregation.	Nitrogen	222-223	pulmonary surfactant-associated protein A	Sus scrofa	254-258
8573180-0	1996	Characterization of a mutant GLUT4 lacking the N-glycosylation site: studies in transfected rat adipose cells.	Nitrogen	47-48	solute carrier family 2 member 4	Rattus norvegicus	29-34
8573180-1	1996	GLUT4, the insulin-responsive glucose transporter expressed primarily in muscle and adipose tissue, contains a single N-glycosylation site.	Nitrogen	118-119	solute carrier family 2 member 4	Rattus norvegicus	0-5
8573180-1	1996	GLUT4, the insulin-responsive glucose transporter expressed primarily in muscle and adipose tissue, contains a single N-glycosylation site.	Nitrogen	118-119	solute carrier family 2 member 4	Rattus norvegicus	11-49
8573180-2	1996	We characterized a mutant GLUT4 lacking the N-glycosylation site (Asn57--&gt;Gln) in primary cultures of rat adipose cells.	Nitrogen	44-45	solute carrier family 2 member 4	Rattus norvegicus	26-31
9774483-8	1998	STX slightly prefer the sixth N-glycosylation site over the fifth N-glycosylation site.	Nitrogen	66-67	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	Homo sapiens	0-3
9802575-2	1998	Sequencing analysis revealed that the open reading frame of feline CD3epsilon consists of 606 base pairs encoding a predicted molecular mass of 25 kDa transmembrane protein which lacks N-glycosylation site.	Nitrogen	185-186	CD3 epsilon subunit of T-cell receptor complex	Homo sapiens	67-77
32043277-8	2021	We conclude that the O2 -sensitive N-degron of VRN2 has a dual function, confining VRN2 to meristems and primordia, where it has specific developmental roles, whilst also permitting broad accumulation outside of meristems in response to environmental cues, leading to other functions.	Nitrogen	35-36	VEFS-Box of polycomb protein	Arabidopsis thaliana	47-51
8568804-7	1996	Among these compounds that had a lower activity toward sigma binding sites, a high 5-HT1A affinity was found for the N-(3-phenylpropyl) derivative 21 (Ki = 4.4 nM) which demonstrated very good selectivity.	Nitrogen	117-118	5-hydroxytryptamine receptor 1A	Homo sapiens	83-89
9833326-10	1998	The results are consistent with a significant change in the conformation of the H2OCbl phosphodiester upon binding to haptocorrin which could be due to a shortening of the axial Co-N bond.	Nitrogen	181-182	transcobalamin 1	Homo sapiens	118-129
32043277-8	2021	We conclude that the O2 -sensitive N-degron of VRN2 has a dual function, confining VRN2 to meristems and primordia, where it has specific developmental roles, whilst also permitting broad accumulation outside of meristems in response to environmental cues, leading to other functions.	Nitrogen	35-36	VEFS-Box of polycomb protein	Arabidopsis thaliana	83-87
33374865-1	2020	Phosphoenolpyruvate carboxylase (PEPC) is an enzyme with key roles in carbon and nitrogen metabolisms.	Nitrogen	81-89	phosphoenolpyruvate carboxylase	Nicotiana tabacum	0-31
29711062-1	1998	A rare, structurally characterized mu1 ,eta1 -hydrazonato complex is a probable intermediate in the Pd-catalyzed N-arylation of hydrazones.	Nitrogen	113-114	secreted phosphoprotein 1	Homo sapiens	40-44
7499420-3	1995	The positions of the four lipophilic domains and the N-glycosylation site of PMP22 are conserved in CL-20, suggesting that it also is an integral membrane glycoprotein.	Nitrogen	53-54	peripheral myelin protein 22	Homo sapiens	77-82
33374865-1	2020	Phosphoenolpyruvate carboxylase (PEPC) is an enzyme with key roles in carbon and nitrogen metabolisms.	Nitrogen	81-89	phosphoenolpyruvate carboxylase	Nicotiana tabacum	33-37
33374906-7	2020	Nitrate assimilation led to excessive ammonium accumulation in the shoot and lower nitrogen uptake, which exacerbated growth retardation of vha-a2 vha-a3.	Nitrogen	83-91	vacuolar proton ATPase A2	Arabidopsis thaliana	140-146
7490293-1	1995	The yeast Kre2p/Mnt1p alpha 1,2-mannosyltransferase is a type II membrane protein with a short cytoplasmic amino terminus, a membrane-spanning region, and a large catalytic luminal domain containing one N-glycosylation site.	Nitrogen	203-204	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	10-15
7490293-1	1995	The yeast Kre2p/Mnt1p alpha 1,2-mannosyltransferase is a type II membrane protein with a short cytoplasmic amino terminus, a membrane-spanning region, and a large catalytic luminal domain containing one N-glycosylation site.	Nitrogen	203-204	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	16-21
7490293-2	1995	Anti-Kre2p/Mnt1p antibodies identify a 60-kD integral membrane protein that is progressively N-glycosylated in an MNN1-dependent manner.	Nitrogen	93-94	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	5-10
7490293-2	1995	Anti-Kre2p/Mnt1p antibodies identify a 60-kD integral membrane protein that is progressively N-glycosylated in an MNN1-dependent manner.	Nitrogen	93-94	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	11-16
9671727-5	1998	The nitrogen status for other nitrogen-responsive processes such as catabolic gene expression and sporulation also is signaled by this tRNA: mutant cells inappropriately induce the nitrogen-repressed gene CAR1 and undergo precocious sporulation in nitrogen-rich media.	Nitrogen	4-12	arginase	Saccharomyces cerevisiae S288C	205-209
9671727-5	1998	The nitrogen status for other nitrogen-responsive processes such as catabolic gene expression and sporulation also is signaled by this tRNA: mutant cells inappropriately induce the nitrogen-repressed gene CAR1 and undergo precocious sporulation in nitrogen-rich media.	Nitrogen	30-38	arginase	Saccharomyces cerevisiae S288C	205-209
9671727-5	1998	The nitrogen status for other nitrogen-responsive processes such as catabolic gene expression and sporulation also is signaled by this tRNA: mutant cells inappropriately induce the nitrogen-repressed gene CAR1 and undergo precocious sporulation in nitrogen-rich media.	Nitrogen	30-38	arginase	Saccharomyces cerevisiae S288C	205-209
9671727-5	1998	The nitrogen status for other nitrogen-responsive processes such as catabolic gene expression and sporulation also is signaled by this tRNA: mutant cells inappropriately induce the nitrogen-repressed gene CAR1 and undergo precocious sporulation in nitrogen-rich media.	Nitrogen	30-38	arginase	Saccharomyces cerevisiae S288C	205-209
7589471-2	1995	It has been suggested that an erythroleukemia cell line with high sensitivity to EPO expresses a high molecular mass form of EPOR, which appears to be a highly N-glycosylated form responsible for EPO-mediated signal transduction [Sawyer and Hankins (1993) Proc.	Nitrogen	160-161	erythropoietin receptor	Homo sapiens	125-129
33374906-7	2020	Nitrate assimilation led to excessive ammonium accumulation in the shoot and lower nitrogen uptake, which exacerbated growth retardation of vha-a2 vha-a3.	Nitrogen	83-91	vacuolar proton ATPase A3	Arabidopsis thaliana	147-153
33375044-3	2020	More recently, OTFTs have been designed as gas sensor devices, displaying remarkable performance for the detection of important target analytes, such as ammonia, nitrogen dioxide, hydrogen sulfide and volatile organic compounds (VOCs).	Nitrogen	162-170	gastrin	Homo sapiens	43-46
7546769-4	1995	We demonstrated that conditions of anoxia (95% nitrogen/5% CO2) or hyperoxia (95% oxygen/5% CO2) independently resulted in the increased expression of both TNF and MIP-1 alpha mRNA and protein from lipopolysaccharide (LPS)-stimulated AMO, as compared with cells cultured in room air.	Nitrogen	47-55	chemokine (C-C motif) ligand 3	Mus musculus	164-175
9717179-5	1998	N-Nitrosation greatly increased the cytotoxicity and mutagenicity of N-methylcarbamates at the hprt locus in Chinese hamster V79 cells.	Nitrogen	0-1	hypoxanthine-guanine phosphoribosyltransferase	Cricetulus griseus	95-99
9635580-1	1998	TER286 is a latent drug activated by human glutathione S-transferase (GST) isoforms P1-1 and A1-1 to produce a nitrogen mustard alkylating agent.	Nitrogen	111-119	glutathione S-transferase kappa 1	Homo sapiens	43-68
9614085-5	1998	K+ starvation and nitrogen starvation hyperpolarize both TRK1 TRK2 and trk1Delta trk2Delta cells, thus suggesting that other proteins, in addition to Trk1p and Trk2p, participate in the control of the membrane potential.	Nitrogen	18-26	Trk2p	Saccharomyces cerevisiae S288C	62-66
9611819-10	1998	Deletion of URE2 in the gln1-37 background prevented repression of gene expression by ammonia, showing that the ammonia-induced repression is not caused by a general stress response but represents a specific signal for nitrogen catabolite regulation.	Nitrogen	219-227	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	24-28
7586625-16	1995	Admission levels of IGFBP-1 correlated to nitrogen loss (negative nitrogen balance) during the first 24 hours after the burn (r = 0.84, P &lt; 0.05).	Nitrogen	42-50	insulin like growth factor binding protein 1	Homo sapiens	20-27
7586625-16	1995	Admission levels of IGFBP-1 correlated to nitrogen loss (negative nitrogen balance) during the first 24 hours after the burn (r = 0.84, P &lt; 0.05).	Nitrogen	66-74	insulin like growth factor binding protein 1	Homo sapiens	20-27
7559434-0	1995	Involvement of nodS in N-methylation and nodU in 6-O-carbamoylation of Rhizobium sp.	Nitrogen	23-24	nodulation methyltransferase NodS	Sinorhizobium fredii NGR234	15-19
33258366-4	2020	However, in the absence of THF, the TiII complex captures N2 to produce the diamagnetic complex [(TptBu,Me)TiCl]2(eta1,eta1;mu2-N2), with a linear Ti N N Ti topology, established by single-crystal X-ray diffraction.	Nitrogen	58-60	secreted phosphoprotein 1	Homo sapiens	114-118
7657826-17	1995	These studies reveal that the expression levels of the two rUT2 transcripts are modulated by different pathways to allow fluid and nitrogen balance to be regulated independently.	Nitrogen	131-139	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	59-63
9571169-0	1998	Dissection of the roles of adenine ring nitrogen (N-1) and exocyclic amino (N-6) moieties in the interaction of 2-5A with RNase L.	Nitrogen	40-48	ribonuclease L	Homo sapiens	122-129
9524122-9	1998	GPR1 RNA was induced when cells were starved for nitrogen and amino acids.	Nitrogen	49-57	Gpr1p	Saccharomyces cerevisiae S288C	0-4
33258366-4	2020	However, in the absence of THF, the TiII complex captures N2 to produce the diamagnetic complex [(TptBu,Me)TiCl]2(eta1,eta1;mu2-N2), with a linear Ti N N Ti topology, established by single-crystal X-ray diffraction.	Nitrogen	58-60	secreted phosphoprotein 1	Homo sapiens	119-123
33352843-4	2020	Subjects had a significantly higher tendency towards CYP-mediated N-demethylation, with the AUC0-8h ratios of the molar concentrations of [Nor-BUP + Nor-BUP-g] to BUP being (3.4 +- 1.9) significantly higher compared with BUP-g to BUP (0.19 +- 0.2).	Nitrogen	66-67	peptidylprolyl isomerase G	Homo sapiens	53-56
9531513-8	1998	The Km for formation of N-dealkylated tolterodine by CYP3A4 was similar to that obtained in human liver microsomes and higher for CYP2C9 and -2C19.	Nitrogen	24-25	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	130-146
7501421-7	1995	These results indicate that reactive nitrogen intermediates contribute to the killing of E. cuniculi by LPS + rIFN-gamma-activated murine peritoneal macrophages in vitro.	Nitrogen	37-45	interferon gamma	Rattus norvegicus	110-120
33403267-2	2020	The advantage of oligo-ester-ether-diol obtained from waste PET glycolysis is its application in r-PUF, generating a durable foam with excellent fire resistance at rather low loadings of phosphorus-nitrogen FRs (P-N FRs), especially in high moisture environments.	Nitrogen	198-206	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	99-102
7599134-0	1995	Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinity.	Nitrogen	110-111	serpin family C member 1	Homo sapiens	25-41
7599134-0	1995	Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinity.	Nitrogen	110-111	serpin family C member 1	Homo sapiens	191-207
7599134-5	1995	Consensus sequences (CSs) of the ATIII N-glycosylation sites are N-X-S for 135 and N-X-T for 96, 155, and 192.	Nitrogen	39-40	serpin family C member 1	Homo sapiens	33-38
9539140-1	1998	Immature Drosophila rhodopsin is N-glycosylated, but undergoes complete deglycosylation during the process of protein maturation.	Nitrogen	33-34	neither inactivation nor afterpotential E	Drosophila melanogaster	20-29
9539140-2	1998	In order to elucidate the site of glycosylation and its role in rhodopsin synthesis, we investigated the in vitro and in vivo synthesis of rhodopsin whose putative N-glycosylation sites (Asn-20 and Asn-196) were replaced by isoleucine.	Nitrogen	164-165	neither inactivation nor afterpotential E	Drosophila melanogaster	139-148
33326776-2	2020	Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine.	Nitrogen	60-61	eukaryotic translation initiation factor 5A	Homo sapiens	111-154
9587785-9	1998	Similarly, the enhanced blood urea nitrogen and serum creatinine levels which are indicative of renal injury showed a reduction of about 50% at a higher dose of Vit.E.	Nitrogen	35-43	vitrin	Rattus norvegicus	161-164
7608102-0	1995	Recognition of nitrogen-responsive upstream activation sequences of Saccharomyces cerevisiae by the product of the GLN3 gene.	Nitrogen	15-23	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	115-119
7608102-1	1995	We describe the purification of the product of the GLN3 gene of Saccharomyces cerevisiae and the demonstration that the purified product, Gln3p, binds specifically to the DNA sequences GATAAG and GATTAG, previously identified as nitrogen-responsive upstream activation sequences (UASN).	Nitrogen	229-237	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	138-143
33326776-2	2020	Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine.	Nitrogen	60-61	eukaryotic translation initiation factor 5A	Homo sapiens	156-161
9442118-7	1998	Four distinct oligosaccharide structures were found to effect CD44-mediated HA binding: (a) the terminal alpha2,3-linked sialic acid on N-linked oligosaccharides inhibited binding; (b) the first N-linked N-acetylglucosamine residue enhanced binding; (c) O-linked glycans on N-deglycosylated CD44 enhanced binding; and (d) N-acetylgalactosamine incorporation into non-N-linked glycans augmented HA binding by cell surface CD44.	Nitrogen	136-137	CD44 antigen	Cricetulus griseus	62-66
7751635-1	1995	A natural N-linked glycosylation site (Asn-Val-Thr) at amino acid positions 18-20 (Kabat"s numbering) was identified in the framework-1 (FR-1) region of the light chain variable (V kappa) domain of a murine anti-B cell lymphoma Ab, LL-2.	Nitrogen	10-11	peroxiredoxin 2, pseudogene 1	Mus musculus	232-236
32977945-0	2020	Identification of N-glycosylation sites on AtERO1 and AtERO2 using a transient expression system.	Nitrogen	18-19	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	43-49
7751635-6	1995	By a single Arg to Asn mutation, an N-linked glycosylation site similar to that of LL-2 was introduced in the FR-1 segment of a nonglycosylated, humanized anti-carcinoembryonic Ag (CEA) Ab, MN-14 (hMN-14).	Nitrogen	36-37	peroxiredoxin 2, pseudogene 1	Mus musculus	83-87
32977945-5	2020	However, the exact N-glycosylation sites on AtERO1 and AtERO2 remains to be determined.	Nitrogen	19-20	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	44-50
9442933-11	1998	In conclusion, this GRF analog increased N digestibility and retention relative to N ingestion and reduced urinary N, P, K, and Cl excretion.	Nitrogen	83-84	growth hormone releasing hormone	Sus scrofa	20-23
9442933-8	1998	The GRF-treated animals ingested less N, excreted less N in urine and feces to retain a similar amount of N than controls.	Nitrogen	38-39	growth hormone releasing hormone	Sus scrofa	4-7
9442933-8	1998	The GRF-treated animals ingested less N, excreted less N in urine and feces to retain a similar amount of N than controls.	Nitrogen	55-56	growth hormone releasing hormone	Sus scrofa	4-7
9442933-8	1998	The GRF-treated animals ingested less N, excreted less N in urine and feces to retain a similar amount of N than controls.	Nitrogen	55-56	growth hormone releasing hormone	Sus scrofa	4-7
9442933-11	1998	In conclusion, this GRF analog increased N digestibility and retention relative to N ingestion and reduced urinary N, P, K, and Cl excretion.	Nitrogen	41-42	growth hormone releasing hormone	Sus scrofa	20-23
9442933-11	1998	In conclusion, this GRF analog increased N digestibility and retention relative to N ingestion and reduced urinary N, P, K, and Cl excretion.	Nitrogen	83-84	growth hormone releasing hormone	Sus scrofa	20-23
8577253-8	1995	Expression of GSY2 is induced by growth to stationary phase, heat shock or nitrogen starvation.	Nitrogen	75-83	glycogen (starch) synthase GSY2	Saccharomyces cerevisiae S288C	14-18
7755594-10	1995	Whether the differential glycosylation of n- and recombinant IFN-gamma (rIFN-gamma) is reflected in their biological activities in tissues or their clinical applicability is not known.	Nitrogen	19-20	interferon gamma	Rattus norvegicus	72-82
7758463-0	1995	Localization of N-glycosylation sites and functional role of the carbohydrate units of GLAST-1, a cloned rat brain L-glutamate/L-aspartate transporter.	Nitrogen	16-17	solute carrier family 1 member 3	Rattus norvegicus	87-94
7758463-3	1995	Besides these two conserved N-glycosylation motifs at Asn206 and Asn216, GLAST-1 possesses an additional one at Asn35.	Nitrogen	28-29	solute carrier family 1 member 3	Rattus norvegicus	73-80
9384596-7	1997	The complete loss of Cln cyclins and the sustained presence of the Clb-cyclin kinase inhibitor Sic1 in starved cells may provide the molecular basis for the G1 arrest caused by nitrogen deprivation.	Nitrogen	177-185	cyclin-dependent protein serine/threonine kinase inhibiting protein SIC1	Saccharomyces cerevisiae S288C	95-99
32977945-6	2020	In this work, using a plant transient expression system, we identified the N-glycosylation sites on both AtERO1 and AtERO2.	Nitrogen	75-76	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	105-111
7891726-4	1995	GLN3 appears to activate their transcription when good nitrogen sources are unavailable, and URE2 appears to repress their transcription when alternative nitrogen sources are not needed.	Nitrogen	55-63	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
7891726-6	1995	Comparison of PUT gene expression in cells grown in repressing or derepressing nitrogen sources, in the absence of the inducer proline, indicated that both PUT1 and PUT2 are regulated by nitrogen repression, although the effect on PUT2 is comparatively small.	Nitrogen	187-195	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	165-169
7891726-7	1995	Recessive mutations in URE2 elevated expression of the PUT1 and PUT2 genes 5- to 10-fold when cells were grown on a nitrogen-repressing medium.	Nitrogen	116-124	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	64-68
32977945-8	2020	Interestingly, we found that Ero1 homologs from human, rice, soybean and Arabidopsis, all have a conserved N-glycosylation site near the inner active site that reduces molecular oxygen and provides the oxidizing equivalents.	Nitrogen	107-108	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	29-33
32977945-9	2020	The identification of N-glycosylation sites on AtERO1/2 proteins will help understand the function of N-glycosylation not only in AtERO1/2, but also in other Ero1 homologs.	Nitrogen	22-23	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	47-55
9548461-5	1997	Moreover, N-linked glycosylation on the cell surface CD38 was not required for the HB-7-induced cell signaling.	Nitrogen	10-11	CD38 molecule	Homo sapiens	53-57
32977945-9	2020	The identification of N-glycosylation sites on AtERO1/2 proteins will help understand the function of N-glycosylation not only in AtERO1/2, but also in other Ero1 homologs.	Nitrogen	22-23	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	130-138
7899074-5	1995	Further analysis of the UGA4 gene revealed that Gln3p, a global nitrogen regulatory protein containing a GATA zinc-finger domain, is required in order to reach high levels of gamma-aminobutyrate-induced transcription.	Nitrogen	64-72	Uga4p	Saccharomyces cerevisiae S288C	24-28
32977945-9	2020	The identification of N-glycosylation sites on AtERO1/2 proteins will help understand the function of N-glycosylation not only in AtERO1/2, but also in other Ero1 homologs.	Nitrogen	22-23	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	158-162
7899074-5	1995	Further analysis of the UGA4 gene revealed that Gln3p, a global nitrogen regulatory protein containing a GATA zinc-finger domain, is required in order to reach high levels of gamma-aminobutyrate-induced transcription.	Nitrogen	64-72	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	48-53
7899074-8	1995	We propose that tight coupling between the UASGABA and UASGATA elements enables the cell to integrate, according to its nitrogen status, the induced expression levels of UGA4.	Nitrogen	120-128	Uga4p	Saccharomyces cerevisiae S288C	170-174
32977945-9	2020	The identification of N-glycosylation sites on AtERO1/2 proteins will help understand the function of N-glycosylation not only in AtERO1/2, but also in other Ero1 homologs.	Nitrogen	102-103	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	47-55
7899075-9	1995	Previous studies have shown that expression supported by 5"-GATA-3"-containing UAS elements requires Gln3p, another global nitrogen regulatory factor containing a GATA zinc-finger domain.	Nitrogen	123-131	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	101-106
9348299-5	1997	The extracellular Thr49 to Ile substitution abrogates one N-glycosylation site in the naturally occurring BALB/c IL-4R as well as in the experimentally point mutated C57BL/6-T49I sIL-4R, and both molecules display a nearly threefold reduction in IL-4-neutralizing activity compared to the C57BL/6 sIL-4R.	Nitrogen	58-59	interleukin 4	Mus musculus	113-117
32977945-9	2020	The identification of N-glycosylation sites on AtERO1/2 proteins will help understand the function of N-glycosylation not only in AtERO1/2, but also in other Ero1 homologs.	Nitrogen	102-103	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	130-138
7861418-3	1995	Increasing in the effective size of the alkyl substituent at the tertiary amine nitrogen atom in the 1,2,3,6-tetrahydro-4-pyridinyl moiety in the 5H-dibenzo[a,d]cycloheptene series reduces the affinity for the dopamine D-4 receptor, but in the dibenz[b,f]oxepin series, no significant change in binding affinity to the dopamine D-4 receptor was observed.	Nitrogen	80-88	dopamine receptor D4	Homo sapiens	210-231
7861418-3	1995	Increasing in the effective size of the alkyl substituent at the tertiary amine nitrogen atom in the 1,2,3,6-tetrahydro-4-pyridinyl moiety in the 5H-dibenzo[a,d]cycloheptene series reduces the affinity for the dopamine D-4 receptor, but in the dibenz[b,f]oxepin series, no significant change in binding affinity to the dopamine D-4 receptor was observed.	Nitrogen	80-88	dopamine receptor D4	Homo sapiens	319-340
32977945-9	2020	The identification of N-glycosylation sites on AtERO1/2 proteins will help understand the function of N-glycosylation not only in AtERO1/2, but also in other Ero1 homologs.	Nitrogen	102-103	endoplasmic reticulum oxidoreductins 1	Arabidopsis thaliana	158-162
7849022-5	1995	To better understand the structural aspects that regulate human CD2 adhesion functions, we had previously determined the solution structure of the protein part of the N-glycosylated adhesion domain of human CD2 (hu-sCD2(105); MW approximately 13.6 kDa) by NMR spectroscopy.	Nitrogen	167-168	CD2 molecule	Homo sapiens	64-67
7849022-5	1995	To better understand the structural aspects that regulate human CD2 adhesion functions, we had previously determined the solution structure of the protein part of the N-glycosylated adhesion domain of human CD2 (hu-sCD2(105); MW approximately 13.6 kDa) by NMR spectroscopy.	Nitrogen	167-168	CD2 molecule	Homo sapiens	207-210
7708046-5	1995	Cumulative nitrogen balance for 2 postburn days in group IGF was significantly higher than group C (p &lt; 0.01).	Nitrogen	11-19	insulin-like growth factor 1	Rattus norvegicus	57-60
9581553-7	1997	When all of the N-glycosylation sites were abolished, 2% and 8% of FR-alpha and FR-beta respectively were expressed on the cell surface compared with the corresponding wild-type proteins; the residual FR polypeptides in the cell lysates were unable to bind [3H]folic acid.	Nitrogen	16-17	rabaptin, RAB GTPase binding effector protein 2	Homo sapiens	67-75
9581553-7	1997	When all of the N-glycosylation sites were abolished, 2% and 8% of FR-alpha and FR-beta respectively were expressed on the cell surface compared with the corresponding wild-type proteins; the residual FR polypeptides in the cell lysates were unable to bind [3H]folic acid.	Nitrogen	16-17	folate receptor beta	Homo sapiens	80-87
9581553-9	1997	Further, in FR-beta the introduction of an additional unnatural site of N-glycosylation resulted in the enhancement of the expression of the cell surface receptor compared with the wild-type protein.	Nitrogen	72-73	folate receptor beta	Homo sapiens	12-19
9581553-10	1997	The results indicate that the total mass of N-glycosylation, not a specific locus of the modification, is critical for the efficient folding and optimal expression of functional FR-alpha and FR-beta.	Nitrogen	44-45	rabaptin, RAB GTPase binding effector protein 2	Homo sapiens	178-186
9581553-10	1997	The results indicate that the total mass of N-glycosylation, not a specific locus of the modification, is critical for the efficient folding and optimal expression of functional FR-alpha and FR-beta.	Nitrogen	44-45	folate receptor beta	Homo sapiens	191-198
32860730-3	2020	However, the relation between M-NPs and the active sites of metal coordinated with nitrogen (MNx) is hard to be established in acid medium due to the poor stability of M-NPs.	Nitrogen	83-91	keratin 86	Homo sapiens	93-96
9421180-2	1997	In response to superfusion of an anoxic artificial cerebral spinal fluid saturated with 95% N2-5% CO2, the excitatory postsynaptic potential (EPSP) generated in hippocampal CA1 neurons by stimulation of the Schaffer collateral/commissural afferent pathway was completely abolished within 10 min of anoxia.	Nitrogen	92-94	carbonic anhydrase 1	Rattus norvegicus	173-176
7825522-6	1995	However, during feeding, IGF-I significantly stimulated exogenous nitrogen utilization by the whole body; and 3) IGF-I reduced the thermogenic effect of feeding.	Nitrogen	66-74	insulin-like growth factor 1	Rattus norvegicus	25-30
31910058-1	2020	Reducted arylamine N-acetyltransferase (NAT1) in breast cancers is associated with poor patient survival.	Nitrogen	19-20	N-acetyltransferase 1	Homo sapiens	40-44
24222057-9	1995	Evidence is presented for the interchange of ring and amine hydrogens in protonated aromatic amines and it is suggested that only the N-protonated species undergoes significant exchange with ND3.	Nitrogen	134-135	mitochondrially encoded NADH dehydrogenase 3	Homo sapiens	191-194
7529492-0	1994	Identification of a human gastric mucin precursor: N-linked glycosylation and oligomerization.	Nitrogen	51-52	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	26-39
9278435-3	1997	Because of the importance of carbohydrate residues for endocytosis and lysosomal targeting, we examined the oligosaccharides of recombinant alpha-L-iduronidase at each of its six N-glycosylation sites.	Nitrogen	179-180	alpha-L-iduronidase	Cricetulus griseus	140-159
32926333-7	2020	Comparable N-glycosylation was also observed in HEK 293 wild-type and knock-out B4GALT1 cells.	Nitrogen	11-12	beta-1,4-galactosyltransferase 1	Homo sapiens	80-87
9290091-8	1997	Nitrogen balance was improved (p &lt; 0.001), and the wet weight of intestine and its mucosa were increased significantly in the burned rats that received IGF-1.	Nitrogen	0-8	insulin-like growth factor 1	Rattus norvegicus	155-160
9290091-13	1997	In conclusion, IGF-1 improved nitrogen balance, promoted the proliferation of intestinal mucosa and reduced the translocation of endotoxin.	Nitrogen	30-38	insulin-like growth factor 1	Rattus norvegicus	15-20
33257855-2	2020	We previously demonstrated perturbed nitrogen metabolism and addiction to an unconventional pathway of pyrimidine synthesis in KRAS/LKB1 co-mutant cancer cells.	Nitrogen	37-45	Kirsten rat sarcoma viral oncogene homolog	Mus musculus	127-131
33248600-14	2020	The treatment containing NH4Cl presented the lowest ADG, G:F, and N-utilization efficiency.	Nitrogen	25-26	ADG	Gallus gallus	52-55
9416005-6	1997	The effect of the nitrogen source on UGA4 permease was studied measuring ALA and GABA uptake rates in cells from media with ammonium, proline and urea as nitrogen sources.	Nitrogen	18-26	Uga4p	Saccharomyces cerevisiae S288C	37-41
9416005-6	1997	The effect of the nitrogen source on UGA4 permease was studied measuring ALA and GABA uptake rates in cells from media with ammonium, proline and urea as nitrogen sources.	Nitrogen	154-162	Uga4p	Saccharomyces cerevisiae S288C	37-41
9416005-8	1997	Moreover, regulation by the nitrogen source on ALA and GABA uptake was also similar, and identical to that described already for UGA4 permease.	Nitrogen	28-36	Uga4p	Saccharomyces cerevisiae S288C	129-133
32703672-5	2020	EPO preconditioning significantly improved renal function and histologic morphology, indicated by reduced blood urea nitrogen (BUN) ([33.12 +- 1.88] vs [16.03 +- 0.91], P < .05) and serum creatinine (Scr) ([190.2 +- 20.23] vs [77.23 +- 5.82], P < .05) levels and histologic injury scores ([3.20 +- 0.78] vs [1.70 +- 0.67], P < .05).	Nitrogen	117-125	erythropoietin	Rattus norvegicus	0-3
9245713-5	1997	In this report we show that the A33 antigen is (I) N-glycosylated, containing approximately 8 K of N-linked carbohydrate and there is no evidence for O-glycosylation, sialylation or glycophosphatidylinositol, and (ii) S-acylated in vitro, incorporating [3H] palmitic acid linked through a hydroxylamine-sensitive thioester bond.	Nitrogen	51-52	glycoprotein A33	Homo sapiens	32-35
33203955-3	2020	Heterologous expression of GPR37L1-eYFP in either HEK293 or U87 glioblastoma cells yielded two cell surface species of approximately equivalent abundance, the larger of which is N-glycosylated at Asn105.	Nitrogen	178-179	G protein-coupled receptor 37 like 1	Homo sapiens	27-34
9204884-6	1997	Nonetheless, anti-RHL-2/3 IgG reduced the binding of 125I-Lf to hepatocytes at 4 degrees C. Exoglycosidases were used to remove terminally-exposed N-acetylneuraminyl, alpha- and beta-galactosyl, and N-acetylhexosaminyl sugars from human and bovine Lf glycans, and lectin blotting confirmed that glycosidase-treated Lfs lacked detectable terminal galactosyl sugars.	Nitrogen	0-1	lactotransferrin	Rattus norvegicus	58-60
33048522-0	2020	Single-Molecule Force Spectroscopy Reveals that the Fe-N Bond Enables Multiple Rupture Pathways of the 2Fe2S Cluster in a MitoNEET Monomer.	Nitrogen	55-56	CDGSH iron sulfur domain 1	Homo sapiens	122-130
9377092-3	1997	In this paper we summarize our efforts to exploit this metabolic pathway to develop latent nitrogen mustard derivatives related to the oxazaphosphorine antitumor agent cyclophosphamide which may target MAO-A and/or MAO-B rich cells.	Nitrogen	91-99	monoamine oxidase A	Homo sapiens	202-207
9200682-3	1997	By comparison with the highly homologous protein FKBP12, containing only the buried Trp, it has been concluded that its weak fluorescence is due to an atypical H-bond interaction involving the indole nitrogen and the Phe129 benzene ring.	Nitrogen	200-208	FKBP prolyl isomerase 1A pseudogene 4	Homo sapiens	49-55
32852729-11	2020	Simply linear regression analysis indicated serum myonectin was negatively correlated body mass index (BMI), total cholesterol, low-density lipoprotein cholesterol, blood urea nitrogen, creatinine, uric acid, and ACR, and positively correlated with glomerular filtration rate, insulin treatment.	Nitrogen	176-184	erythroferrone	Homo sapiens	50-59
9255556-6	1997	Similarly, higher risks of lung or bladder cancer seen at various levels of smoking in association with polymorphism of the glutathione S-transferase gene GSTM1 or NAT1 and NAT2 genes involved in N-acetylation are reviewed.	Nitrogen	164-165	glutathione S-transferase kappa 1	Homo sapiens	124-149
9171383-1	1997	Nitrogen catabolic gene expression in Saccharomyces cerevisiae has been reported to be regulated by three GATA family proteins, the positive regulators Gln3p and Gat1p/Nil1p and the negative regulator Dal80p/Uga43p.	Nitrogen	0-8	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	152-157
9171383-2	1997	We show here that a fourth member of the yeast GATA family, the Dal80p homolog Deh1p, also negatively regulates expression of some, but not all, nitrogen catabolic genes, i.e., GAP1, DAL80, and UGA4 expression increases in a deh1 delta mutant.	Nitrogen	145-153	Uga4p	Saccharomyces cerevisiae S288C	194-198
32951044-2	2020	SUMMARY ANSWER: In this first real-world approach to demonstrate the relationship between air pollutants and serum AMH levels, adverse associations were observed for nitrogen dioxide (NO2) but not with particulate matter.	Nitrogen	166-174	anti-Mullerian hormone	Homo sapiens	115-118
9171427-2	1997	The expression of many nitrogen-regulated genes of Saccharomyces cerevisiae requires activation by GATA factor Gln3p or Nil1p and is prevented by the presence of glutamine in the growth medium.	Nitrogen	23-31	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	111-116
9172050-6	1997	In the present study, a molecular lipophilicity potential is used to compare the hydrophobic properties of 49 "heterocyclic sp2 nitrogen" highly potent PAF antagonists, belonging to six structurally different series (nine hetrazepines, five pyrrolo[1,2-c]thiazoles, 14 carboxamides, nine dihydropyridines, nine pyridinyl-thiazolidines and three imidazo[4,5-c]pyridines).	Nitrogen	128-136	PCNA clamp associated factor	Homo sapiens	152-155
32713238-8	2020	Serum ELA showed significant negative correlations with serum creatinine (r = -0.529, p < .001), blood urea nitrogen (r = -0.575, p < .001), systolic blood pressure (r = -0.455, p < .001), and diastolic blood pressure (r = -0.450, p < .001), and significant positive correlations with hemoglobin (r = 0.523, p < .001) and eGFR (r = 0.728, p < .001).	Nitrogen	108-116	apelin receptor early endogenous ligand	Homo sapiens	6-9
9202738-3	1997	Using a potent and selective inhibitor of human CYP1A2, furafylline, we have shown that N-hydroxylation catalysed by this enzyme is the major pathway of metabolism of MeIQx and PhIP and is solely responsible for their oxidation to mutagenic species.	Nitrogen	88-89	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	48-54
9100005-10	1997	Using NMR relaxation studies, the dynamics of the backbone nitrogens of IRS-1 PTB domain were studied in both the free protein and the protein when complexed to the IL-4 receptor phosphopeptide.	Nitrogen	59-68	insulin receptor substrate 1	Homo sapiens	72-77
9170245-5	1997	In this report it is shown that the formation of this enzyme is dependent upon the functional GLN3 gene and that the response to nitrogen availability is under the control of the URE2 gene product.	Nitrogen	129-137	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	94-98
9127488-6	1997	The results show that the N-linked glycosylation pathways in P. pastoris are substantially different from those found in S. cerevisiae, with shorter Man(alpha 1,6) extensions to the core Man8GN2 and the apparent lack of significant Man(alpha 1,3) additions representing the major processing modality of N-linked glycans in P. pastoris.	Nitrogen	26-27	adrenoceptor alpha 1D	Homo sapiens	236-245
9141686-2	1997	The SHC catalyses the cyclization of squalene to hopanoids, a class of triterpenoid lipids recently discovered in nitrogen-fixing, root-nodule-forming Bradyrhizobium bacteria.	Nitrogen	114-122	squalene--hopene cyclase	Bradyrhizobium diazoefficiens USDA 110	4-7
9068641-8	1997	Further indication of the importance of the RdxB and CcoP proteins was derived from studies of mutant and wild-type cells grown under anoxygenic photosynthetic and nitrogen-fixing conditions.	Nitrogen	164-172	cytochrome-c oxidase, cbb3-type subunit III	Rhodobacter sphaeroides 2.4.1	53-57
9068641-11	1997	This effect was most pronounced when both the rdxB and the ccoP mutations were present together in cells cultured under nitrogen-fixing photosynthetic growth conditions in which spheroidenone represented approximately 90% of the total carotenoid.	Nitrogen	120-128	cytochrome-c oxidase, cbb3-type subunit III	Rhodobacter sphaeroides 2.4.1	59-63
9231341-9	1997	This is indicative of stereoselective involvement of the main enzyme concerned in the N-demethylation of the enantiomers, considered to be CYP 2C11.	Nitrogen	86-87	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	139-147
9231341-10	1997	Anti-CYP 2C11 also partially inhibited the N-demethylation of racemic chlorpheniramine in rat-liver microsomes exposed to phenobarbitone and 3-methylcholanthrene.	Nitrogen	43-44	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	5-13
9231341-12	1997	CYP1A1 did not, however, catalyse the N-demethylation of either enantiomer.	Nitrogen	38-39	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	0-6
9084006-9	1997	RESULTS: Both GH and IGF-1 decreased nitrogen excretion.	Nitrogen	37-45	insulin-like growth factor 1	Rattus norvegicus	21-26
9106207-1	1997	In Saccharomyces cerevisiae, two positive transcription factors of the GATA family, Gln3p and Nil1p/Gat1p, upregulate the expression of multiple nitrogen pathway genes via upstream 5"-GATA-3" sequences.	Nitrogen	145-153	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	84-89
9065690-4	1997	Ume6p, which also controls the expression of early meiotic genes, represses CAR1 expression through a sequence called URS, as a function of nitrogen availability.	Nitrogen	140-148	arginase	Saccharomyces cerevisiae S288C	76-80
9065690-7	1997	The UAS(arg), containing the previously defined "arginine boxes" is the region that responds to the inducer through the action of the ArgRp-Mcm1p proteins, and its deletion alone significantly affects growth on arginine as sole nitrogen source.	Nitrogen	228-236	transcription factor MCM1	Saccharomyces cerevisiae S288C	140-145
9065690-10	1997	Interestingly, we have found that induction of CAR1 expression by arginine in the presence of an optimal nitrogen source is counteracted by Gln3p, independently of its action at the GATAA sequences.	Nitrogen	105-113	arginase	Saccharomyces cerevisiae S288C	47-51
9070359-8	1997	Apparent K(m) and Vmax kinetic constants for N-acetylation were 5- to 10-fold lower for recombinant mouse NAT1 than NAT2.	Nitrogen	45-46	N-acetyl transferase 1	Mus musculus	106-110
9020858-5	1997	Differences between the immunoreactivity of KAP/BAP and LAP with a BAP antibody were mainly attributed to the N-glycosylated moieties of the TNAPs.	Nitrogen	110-111	prohibitin 2	Homo sapiens	48-51
9020858-5	1997	Differences between the immunoreactivity of KAP/BAP and LAP with a BAP antibody were mainly attributed to the N-glycosylated moieties of the TNAPs.	Nitrogen	110-111	LAP	Homo sapiens	56-59
9020858-5	1997	Differences between the immunoreactivity of KAP/BAP and LAP with a BAP antibody were mainly attributed to the N-glycosylated moieties of the TNAPs.	Nitrogen	110-111	prohibitin 2	Homo sapiens	67-70
9189620-8	1997	The cDNA sequence indicated that DSP was a 366-residue protein with several potential N-glycosylation sites, as well as phosphorylation sites, but that the amino acid sequence was dissimilar to that of other known proteins.	Nitrogen	6-7	dentin sialophosphoprotein	Rattus norvegicus	33-36
9008868-4	1997	The calculated MP2/6-311G(2d,p) energies gave the proton affinities of N, C-2, C-3 and C-4 in pyridine as 924, 658, 686 and 637 kJ mol-1, respectively, which were in good agreement with previous experimental and theoretical results.	Nitrogen	71-72	tryptase pseudogene 1	Homo sapiens	15-18
9008868-4	1997	The calculated MP2/6-311G(2d,p) energies gave the proton affinities of N, C-2, C-3 and C-4 in pyridine as 924, 658, 686 and 637 kJ mol-1, respectively, which were in good agreement with previous experimental and theoretical results.	Nitrogen	71-72	complement C4A (Rodgers blood group)	Homo sapiens	87-90
9733063-3	1997	Furthermore, the predicted amino acid sequence of the possum FSHbeta mature protein shows evolutionary conservation of twelve cysteine residues and two potential N-linked glycosylation sites.	Nitrogen	162-163	follicle stimulating hormone subunit beta	Homo sapiens	61-68
9402658-8	1997	The fact that a combination of AcSDKP and captopril switches cycling hematopoietic stem cells out of cycle indicates the importance of the N-active catalytic site of ACE in AcSDKP hydrolysis in vitro.	Nitrogen	139-140	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	Mus musculus	166-169
8870657-2	1996	Our objective was to determine to what extent each of the three sequons for N-linked glycosylation in hLF is actually used.	Nitrogen	76-77	HLF transcription factor, PAR bZIP family member	Homo sapiens	102-105
8813152-2	1996	Recently, the Mac-2-binding protein, a heavily N-glycosylated secreted protein with a subunit Mr of 97,000, was identified as its ligand.	Nitrogen	47-48	galectin 3 binding protein	Homo sapiens	14-35
8889513-1	1996	The CHA1 gene of Saccharomyces cerevisiae encodes the catabolic L-serine (L-threonine) deaminase responsible for the utilization of serine/threonine as nitrogen sources.	Nitrogen	152-160	L-serine/L-threonine ammonia-lyase CHA1	Saccharomyces cerevisiae S288C	4-8
8778603-5	1996	We report here on the long-term outcome in girls with ornithine transcarbamylase deficiency enrolled in studies of treatments designed to activate new pathways of waste-nitrogen excretion.	Nitrogen	169-177	ornithine transcarbamylase	Homo sapiens	54-80
8778603-12	1996	CONCLUSIONS: Girls with symptomatic ornithine transcarbamylase deficiency who are treated with drugs that activate new pathways of waste-nitrogen excretion have fewer hyperammonemic episodes and a reduced risk of further cognitive decline.	Nitrogen	137-145	ornithine transcarbamylase	Homo sapiens	36-62
8896280-0	1996	The S. cerevisiae nitrogen starvation-induced Yvh1p and Ptp2p phosphatases play a role in control of sporulation.	Nitrogen	18-26	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	46-51
8896280-1	1996	Starvation for nitrogen in the absence of a fermentable carbon source causes diploid Saccharomyces cerevisiae cells to leave vegetative growth, enter meiosis, and sporulare; the former nutritional condition also induces expression of the YVH1 gene that encodes a protein phosphatase.	Nitrogen	15-23	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	238-242
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	14-18
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	149-153
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	14-18
8896280-12	1996	Expression of YVH1 and PTP2 was not affected by nitrogen source quality (asparagine compared to proline) suggesting that nitrogen starvation-induced YVH1 and PTP2 expression and sensitivity to nitrogen catabolite repression are on two different branches of the nitrogen regulatory network.	Nitrogen	121-129	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	149-153
21541507-6	1996	The average of T/N ratio was 1.20 for PT-alpha and 1.30 for c-myc.	Nitrogen	17-18	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	60-65
21541507-7	1996	Cases demonstrating a T/N ratio of more than 1.0 were seen in 33 (55%) and 30 (50%) cases for PT-alpha and c-myc, respectively.	Nitrogen	24-25	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	107-112
7999029-5	1994	Both the mature and non-mature forms of the G-CSFR appear to be N-glycosylated, as determined by glycanase digestion and inhibition of glycosylation by tunicamycin.	Nitrogen	64-65	colony stimulating factor 3 receptor (granulocyte)	Mus musculus	44-50
7532057-6	1994	The human IL-11 gene is localized at 19q13.3-13.4, and codes 199 amino acids and 23 kDa with no N glycosylation.	Nitrogen	96-97	interleukin 11	Homo sapiens	10-15
8060318-5	1994	The soluble K-sam protein was highly N-glycosylated like the transmembrane versions, and N-glycosylation appeared to be necessary for its release.	Nitrogen	37-38	fibroblast growth factor receptor 2	Homo sapiens	12-17
7827405-1	1994	The Saccharomyces cerevisiae ALG7, ALG1 and ALG2 genes, whose products function early in the dolichol pathway of protein N-glycosylation, are essential for cell viability, and perturbation in their expression causes G1-specific cell cycle arrest.	Nitrogen	121-122	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	35-39
7827405-1	1994	The Saccharomyces cerevisiae ALG7, ALG1 and ALG2 genes, whose products function early in the dolichol pathway of protein N-glycosylation, are essential for cell viability, and perturbation in their expression causes G1-specific cell cycle arrest.	Nitrogen	121-122	GDP-Man:Man(1)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	44-48
8038219-6	1994	The apparent size of H1 and H2 in Caco-2 cells was not the same as that in HepG2 cells, due to differences in N-linked glycosylation.	Nitrogen	110-111	H1.5 linker histone, cluster member	Homo sapiens	21-30
8207436-4	1994	By deglycosylation of these proteins and by their differential lectin binding, we show that the active BChE is an N-glycosylated protein of the triantennary type, whereas the inactive 75-kDa protein is O-glycosylated.	Nitrogen	114-115	butyrylcholinesterase	Homo sapiens	103-107
8204583-5	1994	Like human hematopoietic cell surface glycoproteins such as glycophorin A and leukosialin, KDN-gp, which is now characterized to contain N-linked complex-type glycan chains as minor components, is heavily O-glycosylated with alpha 2--&gt;8-linked oligo/polyKDN-containing glycan units attached O-glycosidically to Ser/Thr residues.	Nitrogen	93-94	LOC105369247	Homo sapiens	78-89
8050478-7	1994	These results indicate that only one of the two nitrogens on the basic GBR structure is needed for high affinity binding to the dopamine transporter.	Nitrogen	48-57	sodium-dependent dopamine transporter	Macaca fascicularis	128-148
7510585-2	1994	We previously cloned the cDNA of the IA4 protein, coding for a 267-amino-acid type III integral membrane protein, with four transmembrane domains and three possible N-glycosylation sites.	Nitrogen	27-28	CD82 antigen	Mus musculus	37-40
7510585-13	1994	Using this new mAb we were able to biochemically characterize the IA4 antigen as a 28-kDa protein, highly N-glycosylated with different patterns on various cells.	Nitrogen	106-107	CD82 antigen	Mus musculus	66-69
8110752-5	1994	The cDNA for FR-gamma predicts a 243-residue polypeptide with an amino acid sequence homology of 71% and 79% with FR-alpha and FR-beta, respectively, a 23-residue amino-terminal signal peptide, and 3 potential sites for N-linked glycosylation.	Nitrogen	6-7	rabaptin, RAB GTPase binding effector protein 2	Homo sapiens	114-122
8110752-5	1994	The cDNA for FR-gamma predicts a 243-residue polypeptide with an amino acid sequence homology of 71% and 79% with FR-alpha and FR-beta, respectively, a 23-residue amino-terminal signal peptide, and 3 potential sites for N-linked glycosylation.	Nitrogen	6-7	folate receptor beta	Homo sapiens	127-134
8294459-5	1994	The extracellular region of SAP-1 consisted of eight fibronectin type III-like structure repeats and contained multiple N-glycosylation sites.	Nitrogen	120-121	protein tyrosine phosphatase receptor type H	Homo sapiens	28-33
8304968-4	1994	Antibodies raised to CYP2C11 and 2B1/2 inhibited TMO N-demethylation in hepatic microsomes of untreated and phenobarbital-treated rats, respectively.	Nitrogen	53-54	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	21-28
8304968-7	1994	These results indicated that the N-demethylation of TMO is catalysed mainly by CYP2C11 and 2B1 in rat hepatic microsomes, and that human CYP3A4 and an unspecified isoform of the 2C subfamilies contribute to TMO N-demethylation in human liver.	Nitrogen	33-34	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	79-94
7803042-2	1994	Administration of 278 micrograms/day IGF-I, LR3IGF-I or des(1-3)IGF-I following 70% jejuno-ileal resection significantly attenuated malabsorption of fat and nitrogen.	Nitrogen	157-165	insulin-like growth factor 1	Rattus norvegicus	37-42
8111016-4	1994	Mutant strains lacking functional nitrate reductase showed similar accumulation kinetics of these transcripts during both nitrate induction and derepression in nitrogen-free media.	Nitrogen	160-168	uncharacterized protein	Chlamydomonas reinhardtii	34-51
8663127-8	1996	Hydropathy analysis of KCC1 indicates structural homology to NKCC, including 12 transmembrane domains, a large extracellular loop with potential N-linked glycosylation sites, and cytoplasmic N- and C-terminal regions.	Nitrogen	61-62	solute carrier family 12 member 4	Homo sapiens	23-27
8836874-6	1996	Treatment of both cell types with castanospermine, an inhibitor of N-glycosylation, reduced the differences observed in their adhesion to the fibronectin without significantly affecting beta 1 receptors expression at the cell surface.	Nitrogen	67-68	fibronectin 1	Rattus norvegicus	142-153
33143310-6	2020	Accompanying neuroprotection, IL-4 neutralization inhibited activation of microglia/macrophages, reactive oxygen species-derived oxidative damages, production of myeloperoxidase- and inducible nitric oxide synthase-derived reactive nitrogen species and nitrosative damages as analyzed by immunohistochemistry and hydroethidine histochemistry.	Nitrogen	232-240	interleukin 4	Mus musculus	30-34
8847794-9	1996	In the anesthetic management for a patient with ornithine transcarbamylase deficiency, we have to be careful about the nitrogen balance, which can be affected by the kind and doses of anesthetic drugs, to avoid hyperammonemia.	Nitrogen	119-127	ornithine transcarbamylase	Homo sapiens	48-74
8114061-1	1993	The food mutagen/carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) is activated by cytochrome p4501a-2 via N-hydroxylation; various P450s may contribute to detoxification via ring hydroxylation.	Nitrogen	113-114	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	89-108
8301235-10	1993	The fact that the homologous N-linked glycosylation site (Asn-43) is required for both enzyme activity and secretion for human LPL (Semenkovich et al.	Nitrogen	29-30	lipoprotein lipase	Homo sapiens	127-130
32747458-10	2020	These results extend our understanding of the N/OFQ system in brainstem circuits implicated in many neurobehavioral disorders.Significance statement The neuropeptide nociceptin/orphanin FQ (N/OFQ) and its receptor (NOP) are engaged under conditions of stress and are associated with reward processing disorders.	Nitrogen	46-47	prepronociceptin	Rattus norvegicus	166-176
8264536-6	1993	sud1 cells showed additional pleiotropic phenotypes: temperature-sensitive (ts) growth, reduced efficiencies of sporulation, and sensitivity to heat shock and nitrogen starvation.	Nitrogen	159-167	Spt10p	Saccharomyces cerevisiae S288C	0-4
8609406-3	1996	CD2L bound to a different region of CD2 than known ligands and was N-glycosylation dependent.	Nitrogen	67-68	CD2 molecule	Homo sapiens	0-3
8148870-0	1993	Cytochrome P450 mediated metabolism of diazepam in human and rat: involvement of human CYP2C in N-demethylation in the substrate concentration-dependent manner.	Nitrogen	96-97	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	87-92
32535430-4	2020	The adsorption capacities of CO2 CACs-2-800 are 6.22 mmol g-1 (1 bar) and 2.37 mmol g-1 (0.15 bar) at 273 K. CACs-2-800 also have high selectivity of CO2/N2 (SCO2/N2 = 33) and good adsorption-desorption recycle stability.	Nitrogen	154-156	synthesis of cytochrome C oxidase 2	Homo sapiens	158-162
8148870-5	1993	Inhibitions of the N-demethylation by anti-CYP2C antibody and S-mephenytoin also depended on the substrate concentration and was detectable only at a low substrate concentration.	Nitrogen	19-20	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	43-48
8606156-1	1996	In Saccharomyces cerevisiae, carbon and nitrogen metabolisms are connected via the incorporation of ammonia into glutamate; this reaction is catalyzed by the NADP-dependent glutamate dehydrogenase (NADP-GDH) encoded by the GDH1 gene.	Nitrogen	40-48	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	223-227
8606156-5	1996	Finally, we show that a hap2 mutation does not affect expression of other genes involved in nitrogen metabolism (GDH2, GLN1, and GLN3 encoding, respectively, the NAD-GDH, glutamine synthetase, and a general activator of several nitrogen catabolic genes).	Nitrogen	228-236	transcription activator HAP2	Saccharomyces cerevisiae S288C	24-28
8223648-3	1993	Half of the protein purified by immunoaffinity chromatography was shown to be N-glycosylated at the same site as the natural IFN-omega 1.	Nitrogen	78-79	interferon omega 1	Homo sapiens	125-136
8606156-6	1996	The HAP complex is known to regulate expression of several genes involved in carbon metabolism; its role in the control of GDH1 gene expression, therefore, provides evidence for a cross-pathway regulation between carbon and nitrogen metabolisms.	Nitrogen	224-232	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	123-127
32535430-4	2020	The adsorption capacities of CO2 CACs-2-800 are 6.22 mmol g-1 (1 bar) and 2.37 mmol g-1 (0.15 bar) at 273 K. CACs-2-800 also have high selectivity of CO2/N2 (SCO2/N2 = 33) and good adsorption-desorption recycle stability.	Nitrogen	163-165	synthesis of cytochrome C oxidase 2	Homo sapiens	158-162
8105887-3	1993	In order to better understand the structural basis for CD2-CD58-mediated adhesion and the critical role of the carbohydrate moiety in maintaining the functional stability of the molecule, we have determined the secondary structure of the N-glycosylated adhesion domain of human CD2 (hu-sCD2(105)) using NMR spectroscopy.	Nitrogen	238-239	CD2 molecule	Homo sapiens	55-58
33053347-7	2020	Functionally, N-glycosylation at specific sites of the hepatocyte growth factor receptor, a cargo protein of non-exosomal vesicles, facilitates its sorting into vesicles.	Nitrogen	14-15	met proto-oncogene	Mus musculus	55-88
8105887-3	1993	In order to better understand the structural basis for CD2-CD58-mediated adhesion and the critical role of the carbohydrate moiety in maintaining the functional stability of the molecule, we have determined the secondary structure of the N-glycosylated adhesion domain of human CD2 (hu-sCD2(105)) using NMR spectroscopy.	Nitrogen	238-239	CD2 molecule	Homo sapiens	278-281
7505609-5	1993	All polypeptides encoded by the cloned cDNAs share common features with the G protein-coupled receptor superfamily, such as seven putative hydrophobic transmembrane domains and, except for HM74, N-linked glycosylation sites near the N-terminus.	Nitrogen	41-42	hydroxycarboxylic acid receptor 3	Homo sapiens	189-193
8412748-0	1993	Restoration of nitrogen homeostasis in a man with ornithine transcarbamylase deficiency.	Nitrogen	15-23	ornithine transcarbamylase	Homo sapiens	50-76
8412748-1	1993	We evaluated the hypothesis that sodium phenylbutyrate-induced phenylacetylglutamine biosynthesis in a man with partial ornithine transcarbamylase (OTC) deficiency has a dual effect; it provides an additional vehicle for waste nitrogen excretion, and in the process it suppresses the patient"s residual urea N synthesis, which then may be available for N homeostasis if the need arises.	Nitrogen	227-235	ornithine transcarbamylase	Homo sapiens	120-146
8412748-1	1993	We evaluated the hypothesis that sodium phenylbutyrate-induced phenylacetylglutamine biosynthesis in a man with partial ornithine transcarbamylase (OTC) deficiency has a dual effect; it provides an additional vehicle for waste nitrogen excretion, and in the process it suppresses the patient"s residual urea N synthesis, which then may be available for N homeostasis if the need arises.	Nitrogen	227-235	ornithine transcarbamylase	Homo sapiens	148-151
8740443-8	1996	The molecular weight of the proteins (58 and 51 kDa) was reduced to 36 kDa following treatment with N-glycanase but not further reduced after subsequent treatment with neuraminidase and O-glycanase, suggesting that OBCAM has N-glycosylated carbohydrate chains and that its two isoforms are different, at least, in the degree of N-glycosylation.	Nitrogen	225-226	opioid binding protein/cell adhesion molecule like	Bos taurus	215-220
8740443-9	1996	Taken together, these results suggest that OBCAM consists of 58/51 kDa GPI-anchored glycoproteins which are highly N-glycosylated and are expressed mainly in the nervous system.	Nitrogen	115-116	opioid binding protein/cell adhesion molecule like	Bos taurus	43-48
8608002-2	1996	Here, we show that, in transfected mammalian cells, the predominant beta subunit isoform in brain, Kv beta 2, associates with the Kv1.2 alpha subunit early in channel biosynthesis and that Kv beta 2 exerts multiple chaperone-like effects on associated Kv1.2 including promotion of cotranslational N-linked glycosylation of the nascent Kv1.2 polypeptide, increased stability of Kv beta 2/Kv1.2 complexes, and increased efficiency of cell surface expression of Kv1.2.	Nitrogen	297-298	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Homo sapiens	99-108
8608002-2	1996	Here, we show that, in transfected mammalian cells, the predominant beta subunit isoform in brain, Kv beta 2, associates with the Kv1.2 alpha subunit early in channel biosynthesis and that Kv beta 2 exerts multiple chaperone-like effects on associated Kv1.2 including promotion of cotranslational N-linked glycosylation of the nascent Kv1.2 polypeptide, increased stability of Kv beta 2/Kv1.2 complexes, and increased efficiency of cell surface expression of Kv1.2.	Nitrogen	297-298	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Homo sapiens	189-198
8608002-2	1996	Here, we show that, in transfected mammalian cells, the predominant beta subunit isoform in brain, Kv beta 2, associates with the Kv1.2 alpha subunit early in channel biosynthesis and that Kv beta 2 exerts multiple chaperone-like effects on associated Kv1.2 including promotion of cotranslational N-linked glycosylation of the nascent Kv1.2 polypeptide, increased stability of Kv beta 2/Kv1.2 complexes, and increased efficiency of cell surface expression of Kv1.2.	Nitrogen	297-298	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Homo sapiens	189-198
8373419-3	1993	The result suggests that the N-substituted structure of proline immediately following the site is important for cdc2 kinase phosphorylation.	Nitrogen	29-30	cyclin dependent kinase 1	Homo sapiens	112-116
32531582-5	2020	Non-metric multidimensional scaling and distance-based redundancy analysis revealed that microbial communities exhibited significant differentiation (R2 adjusted = 0.73, p = 0.0001) between mine tailings and Und over the different studied sites, which was strongly influenced by changes on physicochemical properties (pH, Corg and Nt contents, the predominance of small-sized particles of silt, and bulk density) and the presence of Se, Cr, Fe, and Ni, even at low concentrations.	Nitrogen	331-333	collagen type XIV alpha 1 chain	Homo sapiens	208-211
8292828-3	1993	Rat CD24 cDNA is homologous to murine and human CD24 gene with respect to the structure of signal peptide, N-glycosylation sites, and possible glycosyl phosphatidylinositol (GPI) linker attaching site, suggesting that rat CD24 is a transducing glycoprotein anchoring membrane via GPI linker.	Nitrogen	11-12	CD24 molecule	Rattus norvegicus	4-8
8820428-2	1996	In this study, we show that human UDP-glucuronosyltransferase 1.4 protein, stably expressed in human embryonic kidney 293 cells, catalyzes the N-glucuronidation of primary, secondary, and tertiary amine substrates.	Nitrogen	143-144	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	34-65
32930574-4	2020	The synergistic effect exists in the MXene/NCF composite when applied to supercapacitors: NCF can provide the additional pseudocapacitance by N atom doping and simultaneously supports the MXene nanosheets to construct the 3D hollow interconnected neuron-like architecture for supplying highly stable, efficient channels for ion diffusion/electron transport and more contact sites, and that the MXene enhances conductivity and hydrophilicity.	Nitrogen	43-44	neutrophil cytosolic factor 4	Homo sapiens	90-93
8676348-4	1996	The obtained results permit a conclusion that the basic nitrogen atom and terminal, bulky cycloimide moiety, but not the 2-pyrimidinyl group, of buspirone are directly involved in the formation of the bioactive complex with 5-Ht1A receptors.	Nitrogen	56-64	5-hydroxytryptamine receptor 1A	Homo sapiens	224-230
7689829-8	1993	There is a single N-glycosylation site in the mouse GM2 activator protein sequence (Asn151-Phe-Thr) which differs in its location from the single site reported in the human GM2 activator protein sequence (Asn63-Val-Thr).	Nitrogen	18-19	cytochrome b5 domain containing 2	Mus musculus	52-55
32895691-5	2020	In contrast, mixed clusters, where HCCH is preferentially ionized over HCN, can grow up to 3 or 4 units long with new carbon-carbon and carbon-nitrogen covalent bonds.	Nitrogen	143-151	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	71-74
7689829-8	1993	There is a single N-glycosylation site in the mouse GM2 activator protein sequence (Asn151-Phe-Thr) which differs in its location from the single site reported in the human GM2 activator protein sequence (Asn63-Val-Thr).	Nitrogen	18-19	cytochrome b5 domain containing 2	Mus musculus	173-176
8102140-1	1993	Cys-1 mutants of recombinant human asparagine synthetase were constructed and their ability to catalyze the glutamine-dependent nitrogen transfer reaction required for asparagine biosynthesis was determined.	Nitrogen	128-136	cystin 1	Homo sapiens	0-5
8628215-2	1996	Induction of SNM1-lacZ fusions was detected in response to nitrogen mustard, cis-platinum (II) diamine dichloride, UV light, and 8-methoxypsoralen + UVA, but not after heat-shock treatment or incubation with 2-dimethylaminoethylchloride, methylmethane sulfonate or 4-nitroquinoline-N-oxide.	Nitrogen	59-67	Snm1p	Saccharomyces cerevisiae S288C	13-17
8845861-14	1996	Intrinsic clearance (Vmax/Km) calculations suggest that N-acetylation of p-aminobenzoic acid and 2-aminofluorene in Syrian hamsters is catalysed primarily by NAT2 (NAT2 15) in rapid acetylators but by NAT1 (NAT1 9) in slow acetylators.	Nitrogen	56-57	arylamine N-acetyltransferase 1	Mesocricetus auratus	201-205
8845861-14	1996	Intrinsic clearance (Vmax/Km) calculations suggest that N-acetylation of p-aminobenzoic acid and 2-aminofluorene in Syrian hamsters is catalysed primarily by NAT2 (NAT2 15) in rapid acetylators but by NAT1 (NAT1 9) in slow acetylators.	Nitrogen	56-57	arylamine N-acetyltransferase 1	Mesocricetus auratus	207-213
8731497-7	1996	The increase of soluble TM in sera paralleled levels of urinary albumin, blood urea nitrogen (BUN), s-creatinine (Cr), and duration of noninsulin-dependent diabetes mellitus (NIDDM).	Nitrogen	84-92	thrombomodulin	Homo sapiens	24-26
8353847-6	1993	Rates of N-acetylation by NAT1 and NAT2 were considerably lower for heterocyclic arylamines such as 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ), particularly those (e.g. IQ) with steric hindrance to the exocyclic amino group.	Nitrogen	9-10	N-acetyltransferase 1	Homo sapiens	26-30
32982240-9	2020	Results: Although all monolayers were shown to prevent amyloid fibrillation, nitrogen-doped graphene (N-Graphene) caused the most instability in the secondary structure of alpha-synuclein amyloids.	Nitrogen	77-85	synuclein alpha	Homo sapiens	172-187
8314788-6	1993	The recombinant cytochrome b558 beta-subunit was heterogeneously N-glycosylated as demonstrated by its susceptibility to cleavage with endoglycosidases F and H. In contrast to the neutrophil cytochrome b558, a portion of the N-linked oligosaccharide was of the high mannose type.	Nitrogen	65-66	CYTB	Spodoptera frugiperda	16-28
32667728-1	2020	Rhodium PC carbene P complexes 1-L {L = PPh 3 , PPh 2 (C 6 F 5 )} react with iso -thiocyanate, carbodiimide and disulphide to enable C-S, C-N and S-S bond cleavage.	Nitrogen	140-141	protein phosphatase 4 catalytic subunit	Homo sapiens	40-45
8496900-10	1993	An angular, cis, (3aR,9bS), 2-propyl, 9-hydroxy, 3-(n-propyl) analog should be selective for the 5-HT1A receptor.	Nitrogen	1-2	5-hydroxytryptamine receptor 1A	Homo sapiens	97-112
8510655-2	1993	Unexpectedly, the HSP150 gene was found to be regulated by heat shock and nitrogen starvation.	Nitrogen	74-82	heat shock protein HSP150	Saccharomyces cerevisiae S288C	18-24
8510655-9	1993	The HSP150 mRNA level was increased by nitrogen limitation at 24 degrees C, even when under the control of a HSP150 promoter region of 137 bp carrying the mutagenized HSE.	Nitrogen	39-47	heat shock protein HSP150	Saccharomyces cerevisiae S288C	4-10
32983644-10	2020	Altered peaks of m6A-modified transcripts were primarily associated with nitrogen compound metabolic process, positive regulation of vascular-associated smooth muscle cell migration, and endoplasmic reticulum organisation.	Nitrogen	73-81	methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit	Homo sapiens	17-20
8484745-1	1993	By culturing with tunicamycin A1, an inhibitor of N-glycosylation, or by sialidase digestion, mouse monocytic cells P388D1 were induced to carry out Fc receptor-mediated phagocytosis of IgG-coated sheep red blood cells.	Nitrogen	50-51	Fc receptor	Mus musculus	149-160
8485158-3	1993	The bovine biglycan protein core has four potential O-linked and two potential N-linked glycosylation sites and is composed of 11 leucine-rich repeat units.	Nitrogen	79-80	biglycan	Bos taurus	11-19
32034976-0	2020	Ablation of the N-terminus of cardiac essential light chain promotes the super-relaxed state of myosin and counteracts hypercontractility in hypertrophic cardiomyopathy mutant mice.	Nitrogen	16-17	myosin heavy chain 14	Homo sapiens	96-102
32034976-4	2020	Our data suggest a new role for the N-terminus of cardiac ELC (N-ELC) in modulation of myosin cross-bridge function in the healthy as well as in HCM myocardium.	Nitrogen	36-37	myosin heavy chain 14	Homo sapiens	87-93
32405873-3	2020	Two nitrogen levels induced expression of some interesting regulating genes, such as USE1, STX1B_2_3, SEC23, SEC24, SEC61A, HSP A1_8, HSP20, and HSP90B/TRA1.	Nitrogen	4-12	heat shock protein 90 alpha family class B member 1	Homo sapiens	145-151
8448380-0	1993	Processing inhibition of N-linked sugar chains associated with induction of Fc receptor-mediated phagocytosis in the mouse monocytoid cells.	Nitrogen	25-26	Fc receptor	Mus musculus	76-87
32952725-3	2020	The advances made in protocols for capillary electrophoresis-laser-induced fluorescence (CE-LIF) measurements of antibody N-glycans have increased the potential for generating large datasets of N-glycosylation values for assessment.	Nitrogen	122-123	LIF interleukin 6 family cytokine	Homo sapiens	92-95
8429824-8	1993	The keto group, the carboxylate group, and the core nitrogen at position 1 are likely to be the most important groups for binding to the active site of CYP1A2, because the molecular electrostatic potential of all inhibitors is very similar to that of caffeine in these regions.	Nitrogen	52-60	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	152-158
32829380-4	2020	Next, overexpression of ELA in the kidney was found to attenuate DOCA/salt-induced hypertension and renal injury, including lower blood pressure, reversed glomerular morphological damage, decreased blood urea nitrogen (BUN), and blocked the accumulation of fibrotic markers.	Nitrogen	209-217	apelin receptor early endogenous ligand	Homo sapiens	24-27
8441751-5	1993	The phosphate oxygens of CTP interact with the amino group of rLys-94, the hydroxyl of rThr-82, and an imidazole nitrogen of rHis-20.	Nitrogen	113-121	solute carrier family 25 member 1	Homo sapiens	25-28
8030424-1	1993	A series of N-derivatives of 2-phenyl-2,3-dihydro-1,3,2(lambda 5)- benzoxazaphosphoryl-4-one and 2-phenyl-10-methyl-3a-triethoxyphosphonio- 1H,2,3,9,10-tetrahydropyrrolo[3,4-b]([1,4]benzoxazepine-1,3,9-trio ne have been prepared.	Nitrogen	12-13	immunoglobulin lambda like polypeptide 1	Homo sapiens	56-64
32875266-1	2020	The complexes of TrR3 (Tr = B and Al; R = H, F, Cl, and Br) with three N-bases (NH3, CH2NH, and HCN) and three O-bases (CH3OH, H2CO, and CO) are utilized to explore the hybridization effect of N and O atoms on the strength, properties, and nature of the triel bond.	Nitrogen	71-72	tRNA-Arg (anticodon TCG) 4-1	Homo sapiens	17-21
7905677-6	1993	Reaction products formed and identified were a) under nitrogen (.CCl3 present)--5-bromo cytosine and cytosine-5-carboxylic acid; b) under air (CCl3O2.	Nitrogen	54-62	C-C motif chemokine ligand 3	Homo sapiens	65-69
32784787-6	2020	The GCE/N-rGO-Au-based sensor operated in a wide linear range of DA (3-100 microM), AA (550-1500 microM), and UA (20-1000 microM) concentrations with a detection limit of 2.4, 58, and 8.7 microM, respectively, and exhibited satisfactory peak potential separation values of 0.34 V (AA-DA), 0.20 V, (DA-UA) and 0.54 V (AA-UA).	Nitrogen	8-9	aminomethyltransferase	Homo sapiens	4-7
32754990-0	2020	Nitrogen-containing flavonoid and their analogs with diverse B-ring in acetylcholinesterase and butyrylcholinesterase inhibition.	Nitrogen	0-8	butyrylcholinesterase	Homo sapiens	96-117
32849349-0	2020	Potential of N2 Gas Flushing to Hinder Dairy-Associated Biofilm Formation and Extension.	Nitrogen	13-15	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	16-19
32849349-5	2020	Here, in light of studies, performed mainly with raw milk, that considered dominant "planktonic" conditions, we reexamine the changes triggered by cold storage alone or combined with nitrogen gas (N2) flushing on bacterial populations and discuss how the observed benefits of the treatment could also contribute to limiting BF formation in dairies.	Nitrogen	197-199	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	192-195
32707739-3	2020	Although N-glycosylation on different AMPAR subunits has been shown to regulate the ER-exit of hetero-oligomers, its role in the ER-exit of homo-oligomers remains unclear.	Nitrogen	9-10	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	38-43
32620165-3	2020	N-linked glycosylation of PD-L1 maintains its protein stability and interaction with its cognate receptor, programmed cell death protein 1 (PD-1), and this in turn promotes evasion of T-cell immunity.	Nitrogen	0-1	CD274 molecule	Homo sapiens	26-31
32620165-6	2020	Notably, the removal of N-linked glycosylation enhances PD-L1 detection in a variety of bioassays and more accurately predicts the therapeutic efficacy of PD-1/PD-L1 inhibitors, suggesting an important clinical implication of PD-L1 N-linked glycosylation.	Nitrogen	0-1	CD274 molecule	Homo sapiens	56-61
32620165-6	2020	Notably, the removal of N-linked glycosylation enhances PD-L1 detection in a variety of bioassays and more accurately predicts the therapeutic efficacy of PD-1/PD-L1 inhibitors, suggesting an important clinical implication of PD-L1 N-linked glycosylation.	Nitrogen	0-1	CD274 molecule	Homo sapiens	160-165
32620165-8	2020	In this review, we highlight the effects of protein glycosylation on cancer immunotherapy using N-linked glycosylation of PD-L1 as an example.	Nitrogen	96-97	CD274 molecule	Homo sapiens	122-127
32026557-6	2020	The 180-amino acid pre-pro-IGF-II translation product can be divided into five domains and include a N-terminal signal peptide of 24 amino acid residues, the 67 amino acid long mature protein, and an 89 residues extension at the COOH terminus, designated as the E-domain.	Nitrogen	101-102	insulin like growth factor 2	Homo sapiens	27-33
32017295-3	2020	The structures of the N-terminus and C-terminus of CENP-I homologs in complex with CENP-H/K have been reported, respectively.	Nitrogen	22-23	centromere protein I	Homo sapiens	51-57
8910950-2	1996	AAF was DNA-reactive after N-hydroxylation by CYP1A2 in the liver and nitrenium ion formation at the target site.	Nitrogen	9-10	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	46-52
32017295-5	2020	Here, we verified a unique helix alpha11, which forms the intramolecular interactions with N-terminal HEAT repeats in fungal CENP-I.	Nitrogen	91-92	centromere protein I	Homo sapiens	125-131
32017295-6	2020	Deletion of the helix alpha11 exposed the hydrophobic surface and resulted in the in vitro protein aggregation of N-terminal HEAT repeats of fungal CENP-I.	Nitrogen	114-115	centromere protein I	Homo sapiens	148-154
31481756-7	2020	In addition, we employed biochemical analysis and observed differential N-linked glycosylation of human MOR N40D.	Nitrogen	72-73	opioid receptor mu 1	Homo sapiens	104-107
7492324-1	1995	The amino acid sequence deduced from the cloned human cDNA of beta-1,4-N-acetylgalactosaminyltransferase (GalNAc-T; EC 2.4.1.92) gene predicted three potential sites for N-linked glycosylation.	Nitrogen	56-57	beta-1,4-N-acetyl-galactosaminyltransferase 1	Homo sapiens	106-114
7592677-0	1995	N-glycosylation of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit is essential for ligand binding and signal transduction.	Nitrogen	0-1	colony stimulating factor 2	Homo sapiens	29-77
7592677-1	1995	The alpha subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF) is a glycoprotein containing 11 potential N-glycosylation sites in the extracellular domain.	Nitrogen	144-145	colony stimulating factor 2	Homo sapiens	44-92
7592677-1	1995	The alpha subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF) is a glycoprotein containing 11 potential N-glycosylation sites in the extracellular domain.	Nitrogen	144-145	colony stimulating factor 2	Homo sapiens	94-100
7568152-0	1995	Role of the GATA factors Gln3p and Nil1p of Saccharomyces cerevisiae in the expression of nitrogen-regulated genes.	Nitrogen	90-98	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	25-30
7568152-1	1995	We have isolated the NIL1 gene, whose product is an activator of the transcription of nitrogen-regulated genes, by virtue of the homology of its zinc-finger domain to that of the previously identified activator, the product of GLN3.	Nitrogen	86-94	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	227-231
7568152-2	1995	Disruption of the chromosomal NIL1 gene enabled us to compare the effects of Gln3p and of Nil1p on the expression of the nitrogen-regulated genes GLN1, GDH2, and GAP1, coding respectively for glutamine synthetase, NAD-linked glutamate dehydrogenase, and general amino acid permease.	Nitrogen	121-129	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	77-82
7568152-2	1995	Disruption of the chromosomal NIL1 gene enabled us to compare the effects of Gln3p and of Nil1p on the expression of the nitrogen-regulated genes GLN1, GDH2, and GAP1, coding respectively for glutamine synthetase, NAD-linked glutamate dehydrogenase, and general amino acid permease.	Nitrogen	121-129	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	146-150
7568152-2	1995	Disruption of the chromosomal NIL1 gene enabled us to compare the effects of Gln3p and of Nil1p on the expression of the nitrogen-regulated genes GLN1, GDH2, and GAP1, coding respectively for glutamine synthetase, NAD-linked glutamate dehydrogenase, and general amino acid permease.	Nitrogen	121-129	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	152-156
7559469-0	1995	Role of N-linked glycosylation in human osteonectin.	Nitrogen	8-9	secreted protein acidic and cysteine rich	Bos taurus	40-51
32428845-11	2020	It is the ring nitrogen of tryptophan in GPx, a histidine in GAPDH and OxyR and a threonine in Prx.	Nitrogen	15-23	periaxin	Homo sapiens	95-98
7662869-2	1995	To account for this red-shift of iodopsin, we had proposed a structural model from retinal analogue experiments, in which iodopsin would have a relatively long distance between the protonated Schiff base nitrogen and the counterion.	Nitrogen	204-212	opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan)	Gallus gallus	33-41
7662869-2	1995	To account for this red-shift of iodopsin, we had proposed a structural model from retinal analogue experiments, in which iodopsin would have a relatively long distance between the protonated Schiff base nitrogen and the counterion.	Nitrogen	204-212	opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan)	Gallus gallus	122-130
32585650-8	2020	This selective manipulation of optical properties in TQDs due to different N-doping pattern can open up new frontiers for rational design of novel optoelectronic devices.	Nitrogen	75-76	DEL10Q26	Homo sapiens	53-57
7589110-0	1995	Role of N-linked glycosylation in expression of E-selectin on human endothelial cells.	Nitrogen	8-9	selectin E	Homo sapiens	48-58
7589110-3	1995	N-Glycosylation of E-selectin was analyzed by endoglycosidase treatment.	Nitrogen	0-1	selectin E	Homo sapiens	19-29
7589110-6	1995	The role of N-linked glycosylation in surface expression and secretion of E-selectin was studied using interleukin-1-stimulated HUVEC, cultured in the presence of the soluble glycosylation inhibitors tunicamycin or castanospermine.	Nitrogen	12-13	selectin E	Homo sapiens	74-84
7589110-8	1995	N-Glycosylation was blocked by tunicamycin, and resulted in a significantly reduced surface expression of E-selectin, whereas castanospermine only marginally reduced E-selectin expression.	Nitrogen	0-1	selectin E	Homo sapiens	106-116
7589110-10	1995	In conclusion, these studies show that E-selectin is heavily glycosylated with complex type N-linked oligosaccharides and that N-glycosylation is important for expression of E-selectin on human endothelial cells.	Nitrogen	92-93	selectin E	Homo sapiens	39-49
32630599-10	2020	Monomeric TFF1 might protect the gastric mucosa as a scavenger for extracellular reactive oxygen/nitrogen species.	Nitrogen	97-105	trefoil factor 1	Mus musculus	10-14
8537187-3	1995	Radiolysis of myoglobin was carried out under air and under nitrogen in phosphate buffer at pH 5 and 7.	Nitrogen	60-68	myoglobin	Homo sapiens	14-23
7650688-7	1995	The area accessible to the basic nitrogen is confined to the region accessible to its counterion on the histamine H1-receptor, i.e., the carboxylate group of Asp116.	Nitrogen	33-41	histamine receptor H1	Homo sapiens	104-125
7649302-0	1995	Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation.	Nitrogen	65-66	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	55-60
7649302-0	1995	Glycoprotein biosynthesis in Saccharomyces cerevisiae: ngd29, an N-glycosylation mutant allelic to och1 having a defect in the initiation of outer chain formation.	Nitrogen	65-66	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	99-103
8097075-3	1993	Standard heparin (hep) and non-anticoagulant N-desulfated acetylated heparin (DSA-hep) significantly reduced the fibronectin content in the conditioned media of subconfluent, confluent, and supraconfluent rat glomerular mesangial cells (MCs) in culture, as assessed by a sandwich ELISA technique.	Nitrogen	45-46	fibronectin 1	Rattus norvegicus	113-124
32360564-7	2020	Genetic ablation of the signal peptide cleavage site blocked N-glycosylation of FNDC5.	Nitrogen	61-62	fibronectin type III domain containing 5	Homo sapiens	80-85
1401917-9	1992	Interestingly, mb-1 and B29 gene products expressed on human cells are much more heterogenously N-glycosylated than their murine B cell counterparts.	Nitrogen	96-97	histocompatibility 2, M region locus 1	Mus musculus	15-19
1401917-9	1992	Interestingly, mb-1 and B29 gene products expressed on human cells are much more heterogenously N-glycosylated than their murine B cell counterparts.	Nitrogen	96-97	CD79b molecule	Homo sapiens	24-27
9373338-5	1995	We now extend these studies and show that the fusion protein, termed IgG3-IL2, is appropriately N-glycosylated within the IgG3 CH2 domain, binds the human high affinity Fc receptor (Fc gamma RI) with an affinity slightly lower than that of IgG3, and is able to activate complement via the classical pathway to lyse antigen coated sheep red blood cells (SRBC).	Nitrogen	96-97	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	69-73
9373338-5	1995	We now extend these studies and show that the fusion protein, termed IgG3-IL2, is appropriately N-glycosylated within the IgG3 CH2 domain, binds the human high affinity Fc receptor (Fc gamma RI) with an affinity slightly lower than that of IgG3, and is able to activate complement via the classical pathway to lyse antigen coated sheep red blood cells (SRBC).	Nitrogen	96-97	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	122-126
9373338-5	1995	We now extend these studies and show that the fusion protein, termed IgG3-IL2, is appropriately N-glycosylated within the IgG3 CH2 domain, binds the human high affinity Fc receptor (Fc gamma RI) with an affinity slightly lower than that of IgG3, and is able to activate complement via the classical pathway to lyse antigen coated sheep red blood cells (SRBC).	Nitrogen	96-97	Fc gamma receptor Ia	Homo sapiens	182-193
9373338-5	1995	We now extend these studies and show that the fusion protein, termed IgG3-IL2, is appropriately N-glycosylated within the IgG3 CH2 domain, binds the human high affinity Fc receptor (Fc gamma RI) with an affinity slightly lower than that of IgG3, and is able to activate complement via the classical pathway to lyse antigen coated sheep red blood cells (SRBC).	Nitrogen	96-97	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	122-126
7782289-8	1995	In each case, an N-glycosylated 27-kDa protein was generated, that, like TIMP-1 and TIMP-2, inhibited collagenase-1, stromelysin-1, and gelatinases A and B.	Nitrogen	17-18	matrix metallopeptidase 3	Mus musculus	117-130
1334528-0	1992	Influence of DNA repair defects (rad1, rad52) on nitrogen mustard mutagenesis in yeast.	Nitrogen	49-57	recombinase RAD52	Saccharomyces cerevisiae S288C	39-44
32505207-7	2020	Transcription factor Gln3, which activates genes subject to nitrogen catabolite repression, was also active for the first hours, even when ammonium and amino acids were still present in media.	Nitrogen	60-68	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	21-25
1445329-4	1992	One N-glycosylation site exists in sEPO-R but the glycosylation did not affect the binding affinity to EPO.	Nitrogen	4-5	erythropoietin	Mus musculus	36-39
1337080-6	1992	(3) For the disaccharides containing the N-sulfated GlcN, the signals of the protons bound to C-2 and C-3 were shifted upfield by 0.6 and 0.15 ppm, respectively, but that of C-1 was shifted downfield by 0.25 ppm when compared with those of the corresponding N-acetylated disaccharides.	Nitrogen	41-42	complement C2	Homo sapiens	94-105
1337080-6	1992	(3) For the disaccharides containing the N-sulfated GlcN, the signals of the protons bound to C-2 and C-3 were shifted upfield by 0.6 and 0.15 ppm, respectively, but that of C-1 was shifted downfield by 0.25 ppm when compared with those of the corresponding N-acetylated disaccharides.	Nitrogen	41-42	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	174-177
1527091-1	1992	Human protein C (HPC) undergoes several post-translational modifications, including gamma-carboxylation, N-linked glycosylation, and internal proteolytic processing.	Nitrogen	105-106	protein C, inactivator of coagulation factors Va and VIIIa	Homo sapiens	6-15
1500196-11	1992	Moreover, liposomal LPS induced a pronounced immune response in CBA/N mice (defective in B lymphocytes of the LyB-5+ subpopulation).	Nitrogen	68-69	B-lymphocyte antigen 5	Mus musculus	110-115
1601876-6	1992	In vivo synthesis studies in the presence and absence of tunicamycin, an inhibitor of N-linked glycosylation, indicate that pro-P34 is 47 kDa.	Nitrogen	86-87	P34 probable thiol protease	Glycine max	128-131
1500365-2	1992	Substitution with a methyl group on the nitrogen atom in the C-2 side chain effectively enhanced stability to renal dehydropeptidase-I as well as introduction of methylene spacer between the aminocarbonyl group and the pyrrolidine ring of the 5"-aminocarbonylpyrrolidin-3"-ylthio group.	Nitrogen	40-48	complement C2	Homo sapiens	61-64
16668807-0	1992	Effects of Nitrate and Ammonium on Gene Expression of Phosphoenolpyruvate Carboxylase and Nitrogen Metabolism in Maize Leaf Tissue during Recovery from Nitrogen Stress.	Nitrogen	152-160	MLO-like protein 4	Zea mays	54-85
1549584-2	1992	Based on the N-linked glycosylation pattern of a well-characterized recombinant gp120, it is likely that N-linked sugars are present at most, if not all, of the consensus glycosylation sites of the heavily glycosylated gp120.	Nitrogen	13-14	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	80-85
1549584-3	1992	In this study, we evaluated the relative importance of each of the 24 N-linked glycosylation sites of gp120 in the molecular clone HXB2 to viral infectivity.	Nitrogen	70-71	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	102-107
1549584-7	1992	We predict that a partially glycosylated gp120 with most of the dispensable N-linked glycosylation sites removed may be a better vaccine candidate than the fully glycosylated gp120.	Nitrogen	76-77	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	41-46
1486334-5	1992	Blood urea nitrogen (BUN) levels were 13.9 +/- 1.1 ng/ml in IGF-I treated rats, which were significantly lower than those of control rats.	Nitrogen	11-19	insulin-like growth factor 1	Rattus norvegicus	60-65
1486334-7	1992	In IGF-I treated rats three-day urinary excretion of nitrogen and creatine were 163.5 +/- 14.6 mg and 9.53 +/- 1.53 mg, which were significantly less than those in control rats.	Nitrogen	53-61	insulin-like growth factor 1	Rattus norvegicus	3-8
1553756-0	1992	Differences between rats and rabbits in hepatic cytosolic glutathione S-transferase expression in response to nitrogen heterocycle and other inducers.	Nitrogen	110-118	hematopoietic prostaglandin D synthase	Rattus norvegicus	58-83
1541391-0	1992	Yeast KRE2 defines a new gene family encoding probable secretory proteins, and is required for the correct N-glycosylation of proteins.	Nitrogen	107-108	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	6-10
1541391-4	1992	At 30 degrees, kre2 mutants showed altered N-linked glycosylation of proteins, as the average size of N-linked outer chains was reduced.	Nitrogen	43-44	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	15-19
1505071-0	1992	Nitrogen mustard-DNA interaction in melphalan-resistant mammary carcinoma cells with elevated intracellular glutathione and glutathione-S-transferase activity.	Nitrogen	0-8	glutathione S-transferase kappa 1	Homo sapiens	124-149
1282970-4	1992	As we have shown that endothelium-derived relaxing factor (EDRF) and other oxides of nitrogen can form adducts with thiols, we hypothesized that EDRF released from normal endothelium S-nitrosates homocysteine, rendering it nontoxic to the endothelium.	Nitrogen	85-93	alpha hemoglobin stabilizing protein	Homo sapiens	145-149
1465072-0	1992	Insulin-like growth factor I and its variant, des(1-3)IGF-I, improve nitrogen balance and food utilization in rats with renal failure.	Nitrogen	69-77	insulin-like growth factor 1	Rattus norvegicus	0-28
1465072-0	1992	Insulin-like growth factor I and its variant, des(1-3)IGF-I, improve nitrogen balance and food utilization in rats with renal failure.	Nitrogen	69-77	insulin-like growth factor 1	Rattus norvegicus	54-59
1465072-5	1992	Also, nitrogen balance was enhanced, particularly in the des(1-3)IGF-I group, in which nitrogen excretion was reduced by 24%, with the low- and high-dose IGF-I groups showing 16 and 18% reductions, respectively.	Nitrogen	6-14	insulin-like growth factor 1	Rattus norvegicus	65-70
1465072-5	1992	Also, nitrogen balance was enhanced, particularly in the des(1-3)IGF-I group, in which nitrogen excretion was reduced by 24%, with the low- and high-dose IGF-I groups showing 16 and 18% reductions, respectively.	Nitrogen	87-95	insulin-like growth factor 1	Rattus norvegicus	65-70
1682800-0	1991	Sequence and expression of GLN3, a positive nitrogen regulatory gene of Saccharomyces cerevisiae encoding a protein with a putative zinc finger DNA-binding domain.	Nitrogen	44-52	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	27-31
1682800-1	1991	The GLN3 gene of Saccharomyces cerevisiae is required for the activation of transcription of a number of genes in response to the replacement of glutamine by glutamate as source of nitrogen.	Nitrogen	181-189	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	4-8
1682800-6	1991	Immunoprecipitation experiments indicated that the GLN3 protein binds the nitrogen upstream activation sequence of GLN1, the gene encoding glutamine synthetase.	Nitrogen	74-82	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	51-55
1682800-6	1991	Immunoprecipitation experiments indicated that the GLN3 protein binds the nitrogen upstream activation sequence of GLN1, the gene encoding glutamine synthetase.	Nitrogen	74-82	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	115-119
1682801-0	1991	Role of the complex upstream region of the GDH2 gene in nitrogen regulation of the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae.	Nitrogen	56-64	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	43-47
1682801-1	1991	We analyzed the upstream region of the GDH2 gene, which encodes the NAD-linked glutamate dehydrogenase in Saccharomyces cerevisiae, for elements important for the regulation of the gene by the nitrogen source.	Nitrogen	193-201	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	39-43
1939167-7	1991	With an antibody generated against the deduced C-terminal end of xP4, the mature polypeptide was investigated by Western analysis revealing N-glycosylation of xP4.	Nitrogen	140-141	trefoil factor 3 gene 8 S homeolog	Xenopus laevis	65-68
1939167-7	1991	With an antibody generated against the deduced C-terminal end of xP4, the mature polypeptide was investigated by Western analysis revealing N-glycosylation of xP4.	Nitrogen	140-141	trefoil factor 3 gene 8 S homeolog	Xenopus laevis	159-162
1723642-6	1991	In this report, we demonstrate that VC1.1 recognizes an N-linked carbohydrate group that is attached to myelin-associated glycoprotein and N-CAM.	Nitrogen	56-57	neural cell adhesion molecule 1	Rattus norvegicus	139-144
1715685-6	1991	Acetylation of the N-terminus of Ala1 and the epsilon-nitrogen of Lys65 decreased the affinity, by 60-90%, of hIGF-II for all of the IGFBPs and receptors.	Nitrogen	54-62	insulin like growth factor 2	Homo sapiens	110-117
1715685-6	1991	Acetylation of the N-terminus of Ala1 and the epsilon-nitrogen of Lys65 decreased the affinity, by 60-90%, of hIGF-II for all of the IGFBPs and receptors.	Nitrogen	54-62	insulin like growth factor binding protein 1	Homo sapiens	133-139
7658166-0	1995	Absence of N-glycosylation at asparagine 43 in human lipoprotein lipase induces its accumulation in the rough endoplasmic reticulum and alters this cellular compartment.	Nitrogen	11-12	lipoprotein lipase	Homo sapiens	53-71
7630919-7	1995	Oxidation of the two benzylic carbon atoms of alpha, alpha"-bis[3-(N,N-diethylcarbamoyl)piperidino]-p-xylene.2HBr (A-1) to form 1,4-bis[3-N,N-diethylcarbamoyl) piperidino]benzenedicarboxamide (A-40K), which has a second set of carbonyl oxygens but lacks basic N atoms, resulted in a remarkable loss of ADP-antagonist potency while retaining PAF-antagonist activity.	Nitrogen	67-68	PCNA clamp associated factor	Homo sapiens	341-344
21556602-8	1995	In contrast, E-selectin binds promiscuously to various types of SLe(x) and SLe(a) epitopes presented at the cell surface through N-linked, O-linked, or lipid-linked structures.	Nitrogen	129-130	selectin E	Homo sapiens	13-23
7532399-8	1995	In addition, high concentrations (100 micrograms/ml) of N-LDL also activate HUVECs by inducing P-selectin expression.	Nitrogen	56-57	selectin P	Homo sapiens	95-105
7768336-0	1995	Identification of N-glycosylation sites in the gonadotropin-releasing hormone receptor: role in receptor expression but not ligand binding.	Nitrogen	18-19	gonadotropin releasing hormone receptor	Mus musculus	47-86
7530279-4	1995	The 46 kDa and 100 kDa isoforms of VCAM-1 were shown to be N-glycosylated, have similar kinetics of biosynthesis, and to be partially shed from the cell surface with a slight reduction of size.	Nitrogen	59-60	vascular cell adhesion molecule 1	Mus musculus	35-41
8750609-2	1995	The pseudodeficiency is due to a single base substitution in the 3"-untranslated region of the ASA gene (1524+95 A--&gt;G) and it has been reported that this mutation (PD2) always occurs on a chromosome carrying a second mutation in the ASA gene (PD1), which abolishes an N-glycosylation site (N350S).	Nitrogen	272-273	PAF1 homolog, Paf1/RNA polymerase II complex component	Homo sapiens	168-171
7983753-9	1995	The native four-domain MHVR has 16 potential N-linked glycosylation sites, including three on the N-terminal domain.	Nitrogen	45-46	carcinoembryonic antigen-related cell adhesion molecule 1	Mus musculus	23-27
7799961-0	1995	The Saccharomyces cerevisiae Leu3 protein activates expression of GDH1, a key gene in nitrogen assimilation.	Nitrogen	86-94	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	66-70
8844804-6	1995	Both N-hydroxylation and mutagenicity of the amines can be almost completely inhibited by furafylline, a potent and highly selective inhibitor of CYP1A2 in man.	Nitrogen	5-6	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	146-152
8844804-7	1995	These data, together with the work of others, show that the N-hydroxylation and hence the mutagenicity of both MeIQx and PhIP in man is catalyzed almost exclusively by CYP1A2.	Nitrogen	60-61	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	168-174
8844810-3	1995	Studies in vitro with human liver have shown that N-hydroxylation catalyzed by CYP1A2 is the major pathway of oxidation of MeQx and PhIP and is solely responsible for the generation of mutagenic species.	Nitrogen	50-51	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	79-85
8844812-4	1995	Using metabolic inhibitors, bile duct ligation, and intravenous dosing studies, a new hypothesis for colorectal carcinogenesis is proposed involving N-oxidation of PhIP by hepatic cytochrome P-4501A2 (CYP1A2) and O-acetylation by the polymorphic acetyltransferase (NAT2).	Nitrogen	149-150	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	180-199
8844812-4	1995	Using metabolic inhibitors, bile duct ligation, and intravenous dosing studies, a new hypothesis for colorectal carcinogenesis is proposed involving N-oxidation of PhIP by hepatic cytochrome P-4501A2 (CYP1A2) and O-acetylation by the polymorphic acetyltransferase (NAT2).	Nitrogen	149-150	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	201-207
7699577-3	1995	Carcinogenic aromatic amines such as heterocyclic aromatic amines and aminoazo dyes induced predominantly cytochrome P450IA2 (CYP1A2), which is responsible for the mutagenic activation and N-hydroxylation of the amines in the rodent.	Nitrogen	189-190	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	126-132
7696570-2	1994	In the rat brain N-IFN-gamma-immunoreactive perikarya were concentrated in the hypothalamic tuberomammillary nuclei; some immunostained neurones were also detected in the dorsal pontine tegmentum.	Nitrogen	17-18	interferon gamma	Rattus norvegicus	19-28
7993626-0	1994	N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1.	Nitrogen	0-1	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	103-108
7993626-1	1994	We investigated the transmembrane topology of the glutamate receptor GluR1 by introducing N-glycosylation sites as reporter sites for an extracellular location of the respective site.	Nitrogen	90-91	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	69-74
7999071-0	1994	A naturally occurring mutation at the second base of codon asparagine 43 in the proposed N-linked glycosylation site of human lipoprotein lipase: in vivo evidence that asparagine 43 is essential for catalysis and secretion.	Nitrogen	89-90	lipoprotein lipase	Homo sapiens	126-144
7999071-4	1994	DNA sequence analysis of the LPL gene from the patient revealed a homozygous nucleotide change: a A--&gt;G transition at nucleotide position 383, resulting in an amino acid substitution of Ser for Asn43, which is believed to be an N-linked glycosylation site of the LPL mature protein.	Nitrogen	1-2	lipoprotein lipase	Homo sapiens	29-32
7999071-4	1994	DNA sequence analysis of the LPL gene from the patient revealed a homozygous nucleotide change: a A--&gt;G transition at nucleotide position 383, resulting in an amino acid substitution of Ser for Asn43, which is believed to be an N-linked glycosylation site of the LPL mature protein.	Nitrogen	1-2	lipoprotein lipase	Homo sapiens	266-269
7930615-0	1994	Engineering and expression of a secreted murine TCR with reduced N-linked glycosylation.	Nitrogen	65-66	T cell receptor alpha variable 6-3	Mus musculus	48-51
7930615-2	1994	Here, we report the engineering and expression of variants of the murine TCR 2B4 in which many of the potential N-linked glycosylation sites were eliminated.	Nitrogen	112-113	T cell receptor alpha variable 6-3	Mus musculus	73-76
7919388-4	1994	We report the presence of a 65-kD precursor of gp91-phox in the membrane fraction of both p22-phox-deficient cell lines, corresponding to the core protein with N-linked carbohydrate side chains in the high mannose form.	Nitrogen	160-161	calcineurin like EF-hand protein 1	Homo sapiens	90-93
7930580-4	1994	The nucleotide sequence of human CD39 includes an open reading frame encoding a putative 510 amino acid protein with six potential N-linked glycosylation sites, 11 Cys residues, and two potential transmembrane regions.	Nitrogen	131-132	ectonucleoside triphosphate diphosphohydrolase 1	Homo sapiens	33-37
7826612-5	1994	The amino acid sequence is 97%, 89%, and 88% homologous to the ovine, human, and rat FSHr respectively, with complete conservation of the 22 cysteine residues in the whole protein and the 3 N-linked glycosylation sites on the extracellular membrane domain.	Nitrogen	190-191	follicle stimulating hormone receptor	Rattus norvegicus	85-89
7937793-0	1994	Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard.	Nitrogen	55-63	cell division cycle 25C	Homo sapiens	12-18
7923569-0	1994	Transcription-independent repair of nitrogen mustard-induced N-alkylpurines in the c-myc gene in Burkitt"s lymphoma CA46 cells.	Nitrogen	36-44	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	83-88
7923569-3	1994	We have examined the removal of nitrogen mustard-induced N-alkylpurines in the actively transcribed/translocated and transcriptionally repressed native alleles of the c-myc gene in Burkitt"s lymphoma, CA46 cells.	Nitrogen	32-40	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	167-172
7923569-6	1994	At the drug exposure examined, nitrogen mustard produced a similar level of N-alkylpurines in the two alleles of c-myc.	Nitrogen	31-39	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	113-118
7923569-7	1994	Also, the kinetics of lesion repair from both c-myc alleles over a 24 h repair incubation period was of the same order of magnitude: approximately 34% and approximately 25% of nitrogen mustard-induced N-alkylpurines were removed by 8 h; approximately 72% and approximately 66% of nitrogen mustard lesions were removed by 24 h from the untranslocated and translocated alleles respectively.	Nitrogen	176-184	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	46-51
7923569-7	1994	Also, the kinetics of lesion repair from both c-myc alleles over a 24 h repair incubation period was of the same order of magnitude: approximately 34% and approximately 25% of nitrogen mustard-induced N-alkylpurines were removed by 8 h; approximately 72% and approximately 66% of nitrogen mustard lesions were removed by 24 h from the untranslocated and translocated alleles respectively.	Nitrogen	280-288	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	46-51
7923569-8	1994	The untranslocated allele did not become transcriptionally activated upon drug treatment and nitrogen mustard produced a suppression of c-myc message levels from the translocated allele.	Nitrogen	93-101	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	136-141
8051068-8	1994	The NH2 terminus, the Arg277 domain, and the N-glycosylation sites of ovine PGHS-1 are part of a large soluble, globular structure in crystalline ovine PGHS-1 (Picot, D., Loll, P. J., and Garavito, M. (1994) Nature, 367, 243-249).	Nitrogen	4-5	prostaglandin-endoperoxide synthase 1	Mus musculus	76-82
8051068-8	1994	The NH2 terminus, the Arg277 domain, and the N-glycosylation sites of ovine PGHS-1 are part of a large soluble, globular structure in crystalline ovine PGHS-1 (Picot, D., Loll, P. J., and Garavito, M. (1994) Nature, 367, 243-249).	Nitrogen	4-5	prostaglandin-endoperoxide synthase 1	Mus musculus	152-158
7954630-6	1994	RESULTS: MCP-1/JE transcripts were not clearly observed in cultured neonatal rat cardiac myocytes; however, its transcripts were clearly detected by exposure to interleukin 1 alpha (100 U.ml-1), lipopolysaccharide (1 microgram.ml-1), or hypoxia (95% N2 + 5% CO2).	Nitrogen	250-252	C-C motif chemokine ligand 2	Rattus norvegicus	9-14
8045902-1	1994	Expression of the nitrogen catabolic genes in Saccharomyces cerevisiae, including those of the gamma-aminobutyric acid (UGA) and allantoin (DAL) pathways, is regulated positively by the GLN3 protein and negatively by the DAL80 protein.	Nitrogen	18-26	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	186-190
12232278-0	1994	Transcriptional and Posttranscriptional Regulation of Nitrogen-Responding Expression of Phosphoenolpyruvate Carboxylase Gene in Maize.	Nitrogen	54-62	MLO-like protein 4	Zea mays	88-119
8021270-2	1994	Recently, we found the occurrence of N-deglycosylating enzyme, peptide:N-glycanase (PNGase), in mammalian cells and observed that PNGase is a rather common enzyme involved in post-translational remodification of proteins (Suzuki, T., Seko, A., Kitajima, K., Inoue, Y., and Inoue, S. (1993) Biochem.	Nitrogen	37-38	N-glycanase 1	Homo sapiens	63-82
8021270-2	1994	Recently, we found the occurrence of N-deglycosylating enzyme, peptide:N-glycanase (PNGase), in mammalian cells and observed that PNGase is a rather common enzyme involved in post-translational remodification of proteins (Suzuki, T., Seko, A., Kitajima, K., Inoue, Y., and Inoue, S. (1993) Biochem.	Nitrogen	37-38	N-glycanase 1	Homo sapiens	84-90
8021270-2	1994	Recently, we found the occurrence of N-deglycosylating enzyme, peptide:N-glycanase (PNGase), in mammalian cells and observed that PNGase is a rather common enzyme involved in post-translational remodification of proteins (Suzuki, T., Seko, A., Kitajima, K., Inoue, Y., and Inoue, S. (1993) Biochem.	Nitrogen	37-38	N-glycanase 1	Homo sapiens	130-136
2052617-10	1991	We conclude that in newborn rat kidney (i) podocalyxin contains both O- and N-linked oligosaccharides [high mannose or hybrid type, biantennary, and complex (sialylated) type], (ii) podocalyxin is sulfated, and (iii) sulfate is located on both O-linked oligosaccharides and on glycopeptides carrying tri- or tetrantennary N-linked structures.	Nitrogen	76-77	podocalyxin-like	Rattus norvegicus	43-54
2015603-8	1991	Thus, increased levels of class alpha GST isozyme may represent a specific mechanism whereby cells can acquire resistance to nitrogen mustards.	Nitrogen	125-133	hematopoietic prostaglandin D synthase	Mus musculus	38-41
1676961-11	1991	Immunization against SRIF had no effect on blood metabolites; however, GRF infusion increased free fatty acids from 157 to 204 microEq/l (SE = 11) and decreased blood urea nitrogen from 4.1 to 3.5 mmol/l (SE = 0.2) from day 1 to day 6, respectively.	Nitrogen	172-180	growth hormone releasing hormone	Sus scrofa	71-74
1847926-2	1991	Using site-directed mutagenesis the N-glycosylation sites of the Mr 46,000 mannose 6-phosphate receptor (MPR 46) were identified as asparagine residues 57, 83, 107, and 113.	Nitrogen	36-37	mannose-6-phosphate receptor, cation dependent	Homo sapiens	105-111
2066676-0	1991	Effect of N-linked glycosylation on hepatic lipase activity.	Nitrogen	10-11	lipase G, endothelial type	Rattus norvegicus	44-50
2066676-8	1991	Thus, N-linked glycosylation of rat HL, while important to lipase secretion, is not essential for the expression of lipase activity.	Nitrogen	6-7	lipase G, endothelial type	Rattus norvegicus	59-65
8023974-3	1994	In rats that received IGF-I 24 h postischemia, serum creatinine and blood urea nitrogen (BUN) values were significantly lower during the subsequent 6 days than in vehicle-treated rats, and incorporation of 5-bromo-2"-deoxyuridine into tubular cells of the regenerating cortex, measured 48 h postischemia, was enhanced.	Nitrogen	79-87	insulin-like growth factor 1	Rattus norvegicus	22-27
32517003-9	2020	Additional tests showed that besides NDVI, this low-cost Ncam was also capable of predicting corn plant nitrogen contents precisely.	Nitrogen	104-112	neural cell adhesion molecule 1	Homo sapiens	57-61
8062506-9	1994	Des-(1-3)-insulin-like growth factor-1 caused a lower and earlier peak in both serum creatinine and blood urea-nitrogen levels, and a more rapid and complete return toward basal values than in untreated animals.	Nitrogen	111-119	insulin-like growth factor 1	Rattus norvegicus	10-38
1996093-5	1991	Analysis of the deduced amino acid sequence of gp34 showed that it lacks typical signal peptides; however, it has a hydrophobic stretch for membrane anchoring and four possible N-linked glycosylation sites at the carboxy-terminal portion, indicating that it belongs to the family of membrane proteins whose carboxy-terminal portion protrudes out of the cell.	Nitrogen	177-178	TNF superfamily member 4	Homo sapiens	47-51
2060596-5	1991	The linkage of an indole ring to a basic nitrogen atom via the 4 position on the indole ring or the absence of an indole ring are two features which lower the affinity for the 5-HT1D receptor, but do not necessarily lower the affinity for the 5-HT1A receptor.	Nitrogen	41-49	5-hydroxytryptamine receptor 1A	Homo sapiens	243-258
32424389-4	2020	Moreover, we recorded for the first time, a new type of bond, namely sodium carbamimidothiocarbonate (e-tU-SCO2- Na+), upon bubbling CO2 in the DMSO solution of tU due to the persistence of the enol form (e-tU) and the better nucleophilicity of sulfur over nitrogen focal points.	Nitrogen	257-265	synthesis of cytochrome C oxidase 2	Homo sapiens	107-111
1996625-5	1991	The nitrogen balances over the last 3 days for the high-dose IGF-I and des-(1-3)IGF-I groups, at 242 +/- 14 and 217 +/- 13 mg/d, respectively, were significantly (P less than 0.05) more positive than the control group at 153 +/- 21 mg/d.	Nitrogen	4-12	insulin-like growth factor 1	Rattus norvegicus	61-66
1996625-5	1991	The nitrogen balances over the last 3 days for the high-dose IGF-I and des-(1-3)IGF-I groups, at 242 +/- 14 and 217 +/- 13 mg/d, respectively, were significantly (P less than 0.05) more positive than the control group at 153 +/- 21 mg/d.	Nitrogen	4-12	insulin-like growth factor 1	Rattus norvegicus	80-85
7522590-0	1994	Pitfalls in the differentiation of N-glycosylation variants of prostate-specific antigen using concanavalin A.	Nitrogen	35-36	kallikrein related peptidase 3	Homo sapiens	63-88
7522590-1	1994	We determined the optimal conditions for the separation of N-glycosylation variants of prostate-specific antigen using concanavalin A. Concanavalin A is a lectin that binds to the terminal sugar residues of glycoproteins.	Nitrogen	59-60	kallikrein related peptidase 3	Homo sapiens	87-112
32487741-14	2020	Using the cannulated pig model, we found that the distinct C/N ratio induced by cecal infusion of corn starch or casein hydrolysate was linearly correlated with microbial metabolites (secondary bile acids) and tight junction proteins (ZO-1 and OCLD).	Nitrogen	61-62	zonula occludens 1	Sus scrofa	235-239
8193137-3	1994	In the present study, we investigated the role of N- and O-glycosylation in intracellular transport and extracellular cleavage-secretion of rabbit testicular ACE.	Nitrogen	50-51	angiotensin-converting enzyme	Oryctolagus cuniculus	158-161
32064788-6	2020	No significant associations were detected between Clavien-Dindo grade and either tumour (T) (P = 0 071) or nodal (N) status (P = 0 882).	Nitrogen	0-1	plakophilin 4	Homo sapiens	93-102
8204093-9	1994	Taken together with previous data, the results indicate a major involvement of CYP1A2 in the high affinity component of all three human hepatic CA N-demethylations.	Nitrogen	147-148	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	79-85
1703479-5	1991	Taken together, these results indicate that the principal IGFBP secreted by Swiss 3T3 cells is probably the N-glycosylated IGFBP-3.	Nitrogen	108-109	insulin-like growth factor binding protein 3	Mus musculus	123-130
32027040-5	2020	Recombinant CTRP6 protein protected against renal I/R injury by the reduction of blood urea nitrogen (BUN) and creatinine levels.	Nitrogen	92-100	C1q and tumor necrosis factor related protein 6	Mus musculus	12-17
1645456-1	1991	We examined the role of N-linked glycosylation of the insulin-like growth factor-II (IGF-II)/mannose 6-phosphate (Man-6-P) receptor in binding of [125I]IGF-II to the receptor.	Nitrogen	24-25	insulin like growth factor 2	Homo sapiens	85-91
1645456-1	1991	We examined the role of N-linked glycosylation of the insulin-like growth factor-II (IGF-II)/mannose 6-phosphate (Man-6-P) receptor in binding of [125I]IGF-II to the receptor.	Nitrogen	24-25	insulin like growth factor 2	Homo sapiens	152-158
1990272-0	1991	The DAL81 gene product is required for induced expression of two differently regulated nitrogen catabolic genes in Saccharomyces cerevisiae.	Nitrogen	87-95	Dal81p	Saccharomyces cerevisiae S288C	4-9
2148939-6	1990	The resulting nitrogen-containing substrates exhibited a high affinity for serum fibronectin but a moderate cell growth.	Nitrogen	14-22	fibronectin 1	Bos taurus	81-92
8181570-2	1994	An enzymatically active complex was isolated from microsomal membranes from Saccharomyces cerevisiae, which is composed of four proteins: Wbp1p and Swp1p (previously found to be encoded by two essential genes necessary for N-glycosylation in vivo and in vitro) and two additional proteins with a molecular mass of 60/62 kDa and 34 kDa.	Nitrogen	223-224	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	138-143
8181570-2	1994	An enzymatically active complex was isolated from microsomal membranes from Saccharomyces cerevisiae, which is composed of four proteins: Wbp1p and Swp1p (previously found to be encoded by two essential genes necessary for N-glycosylation in vivo and in vitro) and two additional proteins with a molecular mass of 60/62 kDa and 34 kDa.	Nitrogen	223-224	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	148-153
7521022-2	1994	Investigators have shown that the N-terminal metabolite of substance P, substance P(1-7), produces naloxone-reversible antinociception when given supraspinally and systemically in mice and hyperalgesia when injected intrathecally in rats.	Nitrogen	34-35	tachykinin 1	Mus musculus	59-70
7521022-2	1994	Investigators have shown that the N-terminal metabolite of substance P, substance P(1-7), produces naloxone-reversible antinociception when given supraspinally and systemically in mice and hyperalgesia when injected intrathecally in rats.	Nitrogen	34-35	tachykinin 1	Mus musculus	72-83
8145237-11	1994	The results are consistent with the hypothesis that CYP1A1 produces NAPQI preferentially because of closer proximity of the heme iron to the amide nitrogen, whereas CYP2B1 produces 3-OH-APAP preferentially because of closer proximity of the heme iron to the phenolic oxygen in this isoform.	Nitrogen	147-155	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	52-58
8117671-6	1994	The C = NH stretching frequencies of iodopsin and bathoiodopsin are at 1644 and 1638 cm-1, respectively, and shift down to 1621 and 1617 cm-1, respectively, when the nitrogen is deuterated.	Nitrogen	166-174	opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan)	Gallus gallus	37-45
2286553-1	1990	The objective of this study was to determine the minimum dosage of recombinant bovine somatotropin (bST) required to elicit maximum depression in plasma urea nitrogen (PUN), an indicator of anabolic activity.	Nitrogen	158-166	somatotropin	Bos taurus	86-98
32060001-3	2020	METHODS: We collected peripheral blood mononuclear cells from healthy donors and patients with HCC and used them to create CAR T cells, based on the hYP7 and HN3 antibodies, which have high affinities for the C-lobe and N-lobe of GPC3, respectively.	Nitrogen	159-160	CXADR pseudogene 1	Homo sapiens	123-126
2082620-0	1990	Mutation of conserved N-glycosylation sites around the CD4-binding site of human immunodeficiency virus type 1 GP120 affects viral infectivity.	Nitrogen	22-23	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	111-116
1700199-9	1990	These results suggest that RbAHPA-PM react with antigenic sites involving N-linked sugar residues of a 140-kd sialoglycoprotein, presumably podocalyxin.	Nitrogen	74-75	podocalyxin-like	Rattus norvegicus	140-151
7507484-4	1994	The cDNA-deduced amino acid sequence revealed that UPII is synthesized as a precursor protein containing a cleavable signal peptide of approximately 26 amino acids, a long pro-sequence of approximately 59 residues harboring three potential N-glycosylation sites, and the mature polypeptide of 100 residues.	Nitrogen	6-7	uroplakin 2	Bos taurus	51-55
31498466-10	2020	In 2-methyl, N-methylaniline the nitrogen atom is pyramidal as usual with the N-methyl opposite to the 2-methyl but in 2-methyl, N,N-dimethyl aniline the NMe2 group is now almost orthogonal to the phenyl plane.	Nitrogen	33-41	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	154-158
7508388-2	1994	Nitric oxide (NO) reductase is an integral membrane component of the anaerobic respiratory chain of Pseudomonas stutzeri that transforms nitrate to dinitrogen (denitrification).	Nitrogen	148-158	cbb3-type cytochrome c oxidase subunit I	Pseudomonas stutzeri	0-27
1698782-6	1990	Interestingly, unlike vertebrate visual pigments, only newly synthesized fly opsin is N-glycosylated, while the mature protein is not.	Nitrogen	86-87	neither inactivation nor afterpotential E	Drosophila melanogaster	77-82
31498466-10	2020	In 2-methyl, N-methylaniline the nitrogen atom is pyramidal as usual with the N-methyl opposite to the 2-methyl but in 2-methyl, N,N-dimethyl aniline the NMe2 group is now almost orthogonal to the phenyl plane.	Nitrogen	13-14	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	154-158
32486402-0	2020	Preparation of High-Nitrogen Ductile Iron by Injecting Nitrogen Gas in Molten Iron.	Nitrogen	20-28	gastrin	Homo sapiens	64-67
2089394-0	1990	New N-substituted derivatives of E-2"- and E-3"-hydroxystilbazoles-(4) of potential antimicrobial activity.	Nitrogen	0-1	small nucleolar RNA, H/ACA box 63	Homo sapiens	43-46
8289183-4	1994	Additional trans-fused analogs from this series, where the nitrogen was substituted with a variety of alkylene imide containing appendages, demonstrated high (0.60-51 nM) affinity and excellent selectivity for the 5-HT1A site.	Nitrogen	59-67	5-hydroxytryptamine receptor 1A	Homo sapiens	214-220
32486402-0	2020	Preparation of High-Nitrogen Ductile Iron by Injecting Nitrogen Gas in Molten Iron.	Nitrogen	55-63	gastrin	Homo sapiens	64-67
32486402-1	2020	High-nitrogen ductile iron (DI) was prepared by a new method of injecting nitrogen gas into molten iron and nodularizing treatment.	Nitrogen	5-13	gastrin	Homo sapiens	83-86
8286614-9	1993	Both Uf and cathepsin D secreted by CHO cells possess N-linked, phosphorylated high-mannose oligosaccharide chains.	Nitrogen	54-55	cathepsin D	Cricetulus griseus	12-23
2123983-5	1990	The 3H-AFB1-metabolite-binding to the nasal glands in vitro was inhibited by the cytochrome P-450-inhibitor metyrapone and by CO- and N2-atmospheres indicating a cytochrome P-450-dependent bioactivation of the AFB1 in these glands.	Nitrogen	134-136	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	162-178
32486402-1	2020	High-nitrogen ductile iron (DI) was prepared by a new method of injecting nitrogen gas into molten iron and nodularizing treatment.	Nitrogen	74-82	gastrin	Homo sapiens	83-86
32486402-3	2020	The graphite morphology gradually deteriorated with the increase in the nitrogen gas injection time.	Nitrogen	72-80	gastrin	Homo sapiens	81-84
32486402-4	2020	The maximum nitrogen and pearlite contents were obtained after 20 min of nitrogen gas injection, and the corresponding tensile strength and elongation of the DI were calculated as 492 MPa and 9.5%, respectively, which were 9.3% and 22% higher than those of the DI prepared without the nitrogen gas injection treatment, respectively.	Nitrogen	12-20	gastrin	Homo sapiens	82-85
32486402-4	2020	The maximum nitrogen and pearlite contents were obtained after 20 min of nitrogen gas injection, and the corresponding tensile strength and elongation of the DI were calculated as 492 MPa and 9.5%, respectively, which were 9.3% and 22% higher than those of the DI prepared without the nitrogen gas injection treatment, respectively.	Nitrogen	73-81	gastrin	Homo sapiens	82-85
2157490-0	1990	Effect of dietary oils on the production of n-3 and n-6 metabolites of leukocyte 5-lipoxygenase in five rat strains.	Nitrogen	24-25	arachidonate 5-lipoxygenase	Rattus norvegicus	81-95
2189790-0	1990	Secretion of N-glycosylated human recombinant interleukin-1 alpha in Saccharomyces cerevisiae.	Nitrogen	13-14	interleukin 1 alpha	Homo sapiens	46-65
2189790-3	1990	Translational fusions to either one of three yeast signal sequences resulted in secretion of bioactive, N-glycosylated hIL-1 alpha.	Nitrogen	104-105	interleukin 1 alpha	Homo sapiens	119-130
8130392-4	1993	Protein C is a heavily post-translationally modified serine protease with four N-glycosylation sites.	Nitrogen	79-80	protein C, inactivator of coagulation factors Va and VIIIa	Homo sapiens	0-9
7504463-2	1993	Along with the structural motifs of a G-protein coupled receptor, sequence analysis reveals that the monkey FSHR is highly homologous to the human FSHR and has specific features such as N-linked glycosylation sites which are identical to the human FSHR but not present in the rat or ovine FSHR.	Nitrogen	186-187	follicle stimulating hormone receptor	Rattus norvegicus	147-151
32374318-1	2020	We propose a universal dimer-doping strategy to improve the photocatalytic water splitting activity of Ru1/TiO2 single-atom catalysts, in which the N atom is simultaneously doped.	Nitrogen	148-149	Scm like with four mbt domains 1	Homo sapiens	103-106
8240300-7	1993	Furthermore, the association of the various glycosylation-deficient forms of the CD-MPR with BiP correlated inversely with their ability to bind Man-6-P. From these results we conclude that N-glycosylation of the bovine CD-MPR facilities the folding of the nascent polypeptide chain into a conformation that is conductive for intracellular transport and ligand binding.	Nitrogen	190-191	mannose-6-phosphate receptor, cation dependent	Homo sapiens	81-87
8246168-6	1993	L-NG-nitroarginine, an inhibitor of nitric oxide synthetase, prevented the improvement of glomerular filtration rate and blood urea nitrogen by IGF-I at 1 mg/kg, suggesting that the ameliorative action on renal function by IGF-I is mediated via nitric oxide, possibly its vasodilating action.	Nitrogen	132-140	insulin-like growth factor 1	Rattus norvegicus	144-149
8395335-6	1993	The mRNA signal was greater in the colonic carcinoma than in paired adjacent normal colonic mucosa in 38 of 42 cases for P0 [tumor/normal (T/N) ratio = 3.0 +/- 0.3, mean +/- SE, P &lt; 0.001] (G. F. Barnard, R. J. Staniunas, S. Bao, K. Mafune, J. L. Gollan, G. D. Steele, Jr., and L. B. Chen, Cancer Res., 52: 3067-3072, 1992), in 25 of 28 cases for L18 (T/N ratio = 3.7 +/- 0.5, P &lt; 0.001), in 27 of 28 cases for L37 (T/N ratio = 5.3 +/- 0.4, P &lt; 0.001), and in 24 of 28 cases for S6 (T/N ratio = 3.1 +/- 0.5, P &lt; 0.01).	Nitrogen	6-7	ribosomal protein L37	Homo sapiens	417-420
2155231-9	1990	The different hGM-CSF forms induced neutrophil superoxide anion production by a variable amount depending on the extent of N-linked glycosylation.	Nitrogen	123-124	colony stimulating factor 2	Homo sapiens	14-21
2137552-0	1990	nit-2, the major nitrogen regulatory gene of Neurospora crassa, encodes a protein with a putative zinc finger DNA-binding domain.	Nitrogen	17-25	nitrilase family member 2	Homo sapiens	0-5
2137552-2	1990	The positive-acting nit-2 regulatory gene is required to turn on the expression of the nitrogen catabolic enzymes during conditions of nitrogen limitation.	Nitrogen	87-95	nitrilase family member 2	Homo sapiens	20-25
2137552-2	1990	The positive-acting nit-2 regulatory gene is required to turn on the expression of the nitrogen catabolic enzymes during conditions of nitrogen limitation.	Nitrogen	135-143	nitrilase family member 2	Homo sapiens	20-25
32523604-6	2020	In this work, we assessed the role of the GTR1 gene on nitrogen consumption under fermentation conditions, using a high sugar concentration medium with nitrogen limitation and in the context of the WE and WA genetic backgrounds.	Nitrogen	152-160	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	42-46
2303708-18	1990	These results indicate that N-linked glycoside moiety of IL-5 molecules may not play an essential role in the expression of its activity.	Nitrogen	28-29	interleukin 5	Mus musculus	57-61
7690438-7	1993	Inhibition of N-linked glycosylation by tunicamycin resulted in the production of identical-sized nascent L-selectin by normal and CLL cells.	Nitrogen	14-15	selectin L	Homo sapiens	106-116
32523604-8	2020	Furthermore, to identify the SNPs responsible for differences in nitrogen consumption during alcoholic fermentation, we studied the polymorphisms present in the GTR1 gene.	Nitrogen	65-73	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	161-165
8395007-9	1993	Gene dosage experiments also showed that pseudohyphal differentiation in response to nitrogen starvation is dependent on the product of CDC55, a putative B regulatory subunit of protein phosphatase 2A, and a synthetic phenotype was observed in elm1 cdc55 double mutants.	Nitrogen	85-93	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	136-141
2268499-3	1990	The human IL-3 gene encodes a protein of 133 amino acids with two conserved cysteine residues and 2 potential N-linked glycosylation sites; human native IL-3 has not been characterized.	Nitrogen	110-111	interleukin 3	Homo sapiens	10-14
8395007-9	1993	Gene dosage experiments also showed that pseudohyphal differentiation in response to nitrogen starvation is dependent on the product of CDC55, a putative B regulatory subunit of protein phosphatase 2A, and a synthetic phenotype was observed in elm1 cdc55 double mutants.	Nitrogen	85-93	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	249-254
32523604-11	2020	Altogether, our results highlight the role of the GTR1 gene on nitrogen consumption in S. cerevisiae under fermentation conditions.	Nitrogen	63-71	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	50-54
8349699-0	1993	N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum.	Nitrogen	0-1	prostaglandin-endoperoxide synthase 1	Mus musculus	19-64
32245759-4	2020	Fluorescence-labeled RAD23 was shown to normally localize in the cytoplasm, to migrate to vacuoles in the absence of carbon, nitrogen, or both, and to enter nuclei under various stresses, which include UVB, a harmful wavelength of sunlight.	Nitrogen	125-133	Rad23p	Saccharomyces cerevisiae S288C	21-26
8349699-6	1993	N-Glycosylation consensus sequences corresponding to the three glycosylation sites of ovine PGH synthase-1 are conserved in the deduced amino acid sequences of PGH synthases-2.	Nitrogen	0-1	prostaglandin-endoperoxide synthase 1	Mus musculus	92-106
8393858-3	1993	Expression of the ecotropic, but not polytropic, envelope surface protein, gp70, interfered with N-linked glycosylation of the permissive mouse, but not the nonpermissive, human transporter.	Nitrogen	97-98	embigin	Mus musculus	75-79
2092960-5	1990	Analysis of calculated charge distribution reveals that the negative charges are localized on the ring nitrogen and on the exocyclic oxygen atoms of A10 and are similar to the corresponding charges computed for some pyrimidine bases.	Nitrogen	103-111	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	149-152
31739013-8	2020	In the meantime, TVP could ameliorate oxidative damage in N2 and daf-2 (-) mutant but fail in daf-16 (-) mutant, which suggested that DAF-16 (FOXO) might affect the antioxidative protection of TVP in C. elegans.	Nitrogen	58-60	Fork-head domain-containing protein;Forkhead box protein O	Caenorhabditis elegans	134-140
33809601-9	2021	These HOTAIR variants were associated with serum hemoglobin (Hgb), luteinizing hormone (LH), total cholesterol (T. chol), and blood urea nitrogen (BUN) levels, as assessed by analysis of variance (ANOVA).	Nitrogen	137-145	HOX transcript antisense RNA	Homo sapiens	6-12
33235627-9	2021	Subsequently, the 47 key genes were identified to be enriched in 13 Gene Ontology (GO) terms and 2 Kyoto Encyclopedia of Genes and Genomes pathways, with the GO terms involving B4GALT1 including positive regulation of developmental processes, protein amino acid terminal glycosylation and protein amino acid terminal N-glycosylation.	Nitrogen	317-318	beta-1,4-galactosyltransferase 1	Homo sapiens	177-184
33235627-11	2021	In conclusion, B4GALT1 and EIF4G1 were indicated to have significant roles in OA, and B4GALT1 may be involved in positive regulation of developmental processes, protein amino acid terminal glycosylation and protein amino acid terminal N-glycosylation.	Nitrogen	235-236	beta-1,4-galactosyltransferase 1	Homo sapiens	86-93
7479385-7	1995	The experimentally determined carbohydrate content of PSA confirms that only one N-glycosylation site is occupied in the protein.	Nitrogen	81-82	kallikrein related peptidase 3	Homo sapiens	54-57
8402054-3	1993	When administered to anaesthetized dogs (0.57 x 10(5) units per kg body-weight over 6h), TNF caused urinary nitrogen excretion to increase (mean(s.e.m.)	Nitrogen	108-116	tumor necrosis factor	Canis lupus familiaris	89-92
8402054-9	1993	The results suggest that nitrogen excreted in the urine during administration of TNF is derived, at least initially, from the intestinal tract.	Nitrogen	25-33	tumor necrosis factor	Canis lupus familiaris	81-84
8341708-9	1993	(iv) Enzymatic deglycosylation and dephosphorylation showed that hmm-EPOR apparently resulted from additional N-linked glycosylation of a 62-kDa EPOR.	Nitrogen	110-111	erythropoietin receptor	Mus musculus	65-73
8341708-9	1993	(iv) Enzymatic deglycosylation and dephosphorylation showed that hmm-EPOR apparently resulted from additional N-linked glycosylation of a 62-kDa EPOR.	Nitrogen	110-111	erythropoietin receptor	Mus musculus	69-73
27519880-5	1993	DGAT activity in the membrane fraction was traced in fungi cultured for different time periods or in media at different carbon to nitrogen (C/N) ratios.	Nitrogen	130-138	diacylglycerol O-acyltransferase 1	Homo sapiens	0-4
27519880-5	1993	DGAT activity in the membrane fraction was traced in fungi cultured for different time periods or in media at different carbon to nitrogen (C/N) ratios.	Nitrogen	142-143	diacylglycerol O-acyltransferase 1	Homo sapiens	0-4
32172452-1	2020	Myoglobin (Mb), generally taken as the molecular model of monomeric globular heme-proteins, is devoted: (i) to act as an intracellular oxygen reservoir, (ii) to transport oxygen from the sarcolemma to the mitochondria of vertebrate heart and red muscle cells, and (iii) to act as a scavenger of nitrogen and oxygen reactive species protecting mitochondrial respiration.	Nitrogen	295-303	myoglobin	Homo sapiens	0-9
8483933-2	1993	The resultant N-glycosylated molecular model is consistent with known properties of gp120 and docks with CD4 with a substantial reduction in the sum of the internal potential energies of the individual proteins (delta E = -200 kcal/mol).	Nitrogen	14-15	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	84-89
8392465-0	1993	Leukemia inhibitory factor, interferon gamma and dexamethasone regulate N-glycosylation of alpha 1-protease inhibitor in human hepatoma cells.	Nitrogen	72-73	LIF interleukin 6 family cytokine	Homo sapiens	0-26
1511866-5	1992	When starved for nitrogen in acetate medium, transformants overproducing hexokinase, phosphoglucose isomerase, and phosphofructokinase sporulate at the same rate and with the same frequency as cells harbouring only the plasmid vector.	Nitrogen	17-25	hexokinase	Saccharomyces cerevisiae S288C	73-83
34974371-4	2022	Higher NH4+ production yield (average value of 0.35 micromol h-1 cm-2, normalized to cathode surface area) and higher faradaic efficiency (FE, 20.25%) were obtained with intermittent addition of N2 and CO2, while the yield and FE were only 0.018 micromol h-1 cm-2 and 4.21% in the absence of CO2.	Nitrogen	195-197	H1.5 linker histone, cluster member	Homo sapiens	61-69
31912134-9	2020	Cytoplasmic NAD(P)-dependent 10-formyl-tetrahydrofolate dehydrogenase (Aldh1/1) and mitochondrial NAD(P)-dependent 10-formyl-tetrahydrofolate dehydrogenase (Aldh1/2) , genes responsible for the catabolism of 10-formylTHF, were very weakly expressed in PP, low in livers of F and N, and reached the significantly higher adult levels in J.	Nitrogen	12-13	aldehyde dehydrogenase 2 family member	Rattus norvegicus	71-155
34742757-5	2022	Hydrochar prepared by microwave-assisted hydrothermal carbonization of corn cob at 230  C presents noticeable environmental advantages because it contains the lowest ash and nitrogen contents (0.5% and 0.5%, respectively) and lower sulfur content (0.05%).	Nitrogen	174-182	metabolism of cobalamin associated B	Homo sapiens	76-79
8385052-4	1993	Bovine u-PA and its cell-surface receptor display one and six potential sites of N-linked glycosylation, respectively.	Nitrogen	81-82	plasminogen activator, urokinase	Bos taurus	7-11
31912134-9	2020	Cytoplasmic NAD(P)-dependent 10-formyl-tetrahydrofolate dehydrogenase (Aldh1/1) and mitochondrial NAD(P)-dependent 10-formyl-tetrahydrofolate dehydrogenase (Aldh1/2) , genes responsible for the catabolism of 10-formylTHF, were very weakly expressed in PP, low in livers of F and N, and reached the significantly higher adult levels in J.	Nitrogen	12-13	aldehyde dehydrogenase 2 family member	Rattus norvegicus	157-164
32324955-10	2020	Both u-hemojuvelin and UHCR were significantly correlated with high blood urea nitrogen, plasma creatinine, and plasma phosphate concentrations and with low hematocrit (Hct), red blood cell (RBC) count, and plasma albumin concentration.	Nitrogen	79-87	hemojuvelin BMP co-receptor	Homo sapiens	7-18
8440712-12	1993	In addition, S. cerevisiae Faa1p is better able to direct myristoyl-CoA to the bacteria"s phospholipid biosynthetic pathways than FadD, while FadD is more efficient at directing myristoyl-CoA to the genetically engineered protein N-myristoylation pathway.	Nitrogen	230-231	long-chain fatty acid-CoA ligase FAA1	Saccharomyces cerevisiae S288C	27-32
8440724-7	1993	Myosin containing phosphorylated N-smooth/C-skeletal or skeletal LCs, in contrast, is locked in the "off" state.	Nitrogen	33-34	myosin heavy chain 14	Homo sapiens	0-6
8416917-5	1993	In the presence of N-fMet-tRNAfMet and poly(A,U,G) or in the presence of N-acetyl-Phe-tRNAPhe and poly(U), initiation factor IF2 causes an additional decrease of the uncoupled EF-G GTPase activity.	Nitrogen	19-20	G elongation factor mitochondrial 1	Homo sapiens	176-180
34861499-7	2022	Regarding nitrogen removal, the association of TF with one stage of partially saturated vertical TW was found to achieve around 79% of nitrification in average and up to 92% in some cases.	Nitrogen	10-18	coagulation factor III, tissue factor	Homo sapiens	47-49
34861499-8	2022	In the configurations where TF was associated to 2 successive stages of TW, almost all total nitrogen removal by nitrification/denitrification was achieved at the outlet of the first-stage TW.	Nitrogen	93-101	coagulation factor III, tissue factor	Homo sapiens	28-30
34610397-8	2022	(2) The coordination between O, N atoms of EDTMPA and heavy metal ions (Pb2+, Cd2+, Cu2+) resulted in spontaneous adsorption.	Nitrogen	32-33	CD2 molecule	Homo sapiens	78-81
31885188-3	2020	Although transitory AT deficiencies and congenital disorders of the N-glycosylation pathways (CDG) have been recently reported as causes of AT deficiency, the current AT clinical screening still only includes anti-FXa activity.	Nitrogen	68-69	serpin family C member 1	Homo sapiens	140-142
34438149-4	2021	In this study, a microcosm experiment with different initial DOM contents elucidated that the biomass, and biomass nitrogen and phosphorus contents were greatly influenced by humic-like substances (C2 and C3), while the growth of periphytic biofilms increased the contents of humic-like (C1 and C2) and tryptophan-like substances (C5) in soil.	Nitrogen	115-123	complement C2	Homo sapiens	198-207
8443294-2	1993	It has been suggested that the induction of ornithine decarboxylase (ODC) activity during pregnancy might contribute to the low ureagenic flux that enables the pregnant mother to spare nitrogen and support growth.	Nitrogen	185-193	ornithine decarboxylase 1	Rattus norvegicus	44-67
8443294-2	1993	It has been suggested that the induction of ornithine decarboxylase (ODC) activity during pregnancy might contribute to the low ureagenic flux that enables the pregnant mother to spare nitrogen and support growth.	Nitrogen	185-193	ornithine decarboxylase 1	Rattus norvegicus	69-72
8416910-0	1993	Regulatory circuit for responses of nitrogen catabolic gene expression to the GLN3 and DAL80 proteins and nitrogen catabolite repression in Saccharomyces cerevisiae.	Nitrogen	36-44	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	78-82
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	62-66
8416910-6	1993	Expression of GLN1 and GDH2 exhibited parallel responses to the provision of asparagine and glutamine as nitrogen sources but did not follow the regulatory responses noted above for the nitrogen catabolic genes such as DAL5.	Nitrogen	105-113	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	14-18
8416910-6	1993	Expression of GLN1 and GDH2 exhibited parallel responses to the provision of asparagine and glutamine as nitrogen sources but did not follow the regulatory responses noted above for the nitrogen catabolic genes such as DAL5.	Nitrogen	105-113	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	23-27
8423765-13	1993	Both CYP1A2 and CYP3A4 catalyzed N-dealkylation of propafenone, with specific activities of 0.32 pmol/min/pmol of P450 and 0.16 pmol/min/pmol of P450, respectively.	Nitrogen	33-34	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	5-11
1465411-3	1992	Compared to rats administered vehicle, rats administered IGF-I (100 micrograms/day via continuous subcutaneous infusion) had significantly lower serum creatinine and blood urea nitrogen levels over the course of 7 days postocclusion.	Nitrogen	177-185	insulin-like growth factor 1	Rattus norvegicus	57-62
34897456-4	2022	We found that N had significant impacts on the LES and RES traits and on the relationships among them.	Nitrogen	14-15	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	47-50
34846149-4	2021	Within the context of a planar arrangement, the pi-hole above the N in NO2OF, N(CN)3, and CF3NO2 is also capable of forming a pnicogen bond, the strongest of which amounts to 11 kcal/mol with NMe3 as base.	Nitrogen	78-79	NME/NM23 nucleoside diphosphate kinase 3	Homo sapiens	192-196
32297634-6	2020	Among numerous target pathways, we focused on nitrogen metabolism, which remains relatively unexplored compared with other possible miR-21-mediated pathways; hence, we aimed to determine novel target genes of miR-21 related to nitrogen metabolism.	Nitrogen	46-54	microRNA 21	Homo sapiens	209-215
34888887-4	2021	RESULTS: Compared with CRU treatment, CRU + FA treatment significantly increased auxin, nitrate reductase, and glutamate dehydrogenase in leaf by 35.4%, 43.9%, 40.8% and 19.5%, respectively, as well as, the relative content of the leaf chlorophyll and photosynthetic rate by 14.8% and 45.6%, respectively, at 12-leaf collar stage; the carbon/nitrogen (C/N) metabolic process was significantly enriched in CRU + FA treatment by 312 and 418 genes, according to transcriptome profiles of C/N metabolic in leaves from various fertilizer treated maize; maize yield and NUE of CRU + FA treatment were increased by 6.3% and 38.4%, respectively.	Nitrogen	342-350	nitrate reductase [NADH] 1	Zea mays	88-105
1452344-5	1992	Similar results were observed after intraperitoneal injection of a competitive inhibitor of L-arginine, NG-monomethyl-L-arginine, together with rIFN-gamma, demonstrating that in vivo L-arginine-derived reactive nitrogen intermediates are essential for the induction of toxoplasmastatic activity.	Nitrogen	211-219	interferon gamma	Rattus norvegicus	144-154
16653241-0	1992	Glutamine Induces the N-Dependent Accumulation of mRNAs Encoding Phosphoenolpyruvate Carboxylase and Carbonic Anhydrase in Detached Maize Leaf Tissue.	Nitrogen	22-23	MLO-like protein 4	Zea mays	65-96
34762398-2	2021	The open approach to the active site is consistent with the recent discovery that ADO catalyzes not only the conversion of cysteamine to hypotaurine but also the oxidation of N-terminal cysteine (Nt-Cys) peptides to their corresponding sulfinic acids as part of the eukaryotic N-degron pathway.	Nitrogen	277-278	2-aminoethanethiol dioxygenase	Homo sapiens	82-85
32297634-6	2020	Among numerous target pathways, we focused on nitrogen metabolism, which remains relatively unexplored compared with other possible miR-21-mediated pathways; hence, we aimed to determine novel target genes of miR-21 related to nitrogen metabolism.	Nitrogen	227-235	microRNA 21	Homo sapiens	132-138
16653241-1	1992	We have used detached leaves to study the N-dependent control of expression of phosphoenolpyruvate carboxylase (PEPC) and carbonic anhydrase (CA) genes in maize (Zea mays L. cv Golden Cross Bantam T51).	Nitrogen	42-43	MLO-like protein 4	Zea mays	79-110
16653241-1	1992	We have used detached leaves to study the N-dependent control of expression of phosphoenolpyruvate carboxylase (PEPC) and carbonic anhydrase (CA) genes in maize (Zea mays L. cv Golden Cross Bantam T51).	Nitrogen	42-43	MLO-like protein 4	Zea mays	112-116
32297634-6	2020	Among numerous target pathways, we focused on nitrogen metabolism, which remains relatively unexplored compared with other possible miR-21-mediated pathways; hence, we aimed to determine novel target genes of miR-21 related to nitrogen metabolism.	Nitrogen	227-235	microRNA 21	Homo sapiens	209-215
16653241-2	1992	Following supplementation with an N-source and zeatin, PEPC and CA mRNA levels increased in leaves detached from N-deficient maize plants.	Nitrogen	34-35	MLO-like protein 4	Zea mays	55-59
16653241-4	1992	Glutamine levels in detached maize leaves treated with various N sources in the presence or absence of MSX correlated with the levels of PEPC and CA mRNA.	Nitrogen	63-64	MLO-like protein 4	Zea mays	137-141
16653241-5	1992	We conclude that glutamine is the most likely effector for controlling the N-dependent expression of PEPC and CA in maize plants.	Nitrogen	75-76	MLO-like protein 4	Zea mays	101-105
34787415-0	2021	Transition Metal-Modified Co4 Clusters Supported on Graphdiyne as an Effective Nitrogen Reduction Reaction Electrocatalyst.	Nitrogen	79-87	complement C4A (Rodgers blood group)	Homo sapiens	26-29
32297634-11	2020	In conclusion, we identified a novel therapeutic strategy to improve cardiac function by regulating the expression of miR-21 with PB-sEVs as an miR-21 or anti-miR-21 delivery vehicle and confirmed the miR-21-associated nitrogen metabolic disorders in MI.	Nitrogen	219-227	microRNA 21	Homo sapiens	118-124
32350295-0	2020	N-glycosylation of alpha1D-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis.	Nitrogen	0-1	adrenoceptor alpha 1D	Homo sapiens	19-46
34861885-0	2021	ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism.	Nitrogen	76-84	argininosuccinate synthase 1	Homo sapiens	0-4
34549452-0	2021	Characteristics of alpha2,3-sialyl N-glycosylated PSA as a biomarker for clinically significant prostate cancer in men with elevated PSA level.	Nitrogen	35-36	immunoglobulin kappa variable 2-24	Homo sapiens	19-27
1360027-6	1992	The introduction of two n-propyl groups (18a) on the nitrogen atom reduces by one-half and doubles the affinity for D-1 and D-2 binding sites, respectively.	Nitrogen	53-61	solute carrier family 3 member 1	Rattus norvegicus	116-127
1385399-0	1992	N-glycosylation is required for human CD2 immunoadhesion functions.	Nitrogen	0-1	CD2 molecule	Homo sapiens	38-41
1385399-2	1992	Two domains comprise the CD2 extracellular segment, with all adhesion functions localized to the amino-terminal domain that contains a single N-glycosylation site at Asn65.	Nitrogen	142-143	CD2 molecule	Homo sapiens	25-28
1385399-6	1992	Based on a model of human CD2 secondary structure, we propose that N-glycosylation is required for stabilizing domain 1 in the human receptor.	Nitrogen	67-68	CD2 molecule	Homo sapiens	26-29
1385399-7	1992	Thus, N-glycosylation is essential for human CD2 adhesion functions.	Nitrogen	6-7	CD2 molecule	Homo sapiens	45-48
1337000-0	1992	Proton, carbon, and nitrogen chemical shifts accurately delineate differences and similarities in secondary structure between the homologous proteins IRAP and IL-1 beta.	Nitrogen	20-28	interleukin 1 receptor antagonist	Homo sapiens	150-154
34549452-0	2021	Characteristics of alpha2,3-sialyl N-glycosylated PSA as a biomarker for clinically significant prostate cancer in men with elevated PSA level.	Nitrogen	35-36	kallikrein related peptidase 3	Homo sapiens	50-53
34748700-8	2021	A theoretically unexpected finding is reported for the first time about the effect of the GC carrier gas (He, Ne, and N2) on the sensitivity of the analysis in the presence of the gas driving the supersonic jet (He, Ne, and N2) in the GC-MRR.	Nitrogen	118-120	gastrin	Homo sapiens	101-104
34748700-8	2021	A theoretically unexpected finding is reported for the first time about the effect of the GC carrier gas (He, Ne, and N2) on the sensitivity of the analysis in the presence of the gas driving the supersonic jet (He, Ne, and N2) in the GC-MRR.	Nitrogen	224-226	gastrin	Homo sapiens	180-183
34783117-3	2022	The synthesized nitrogen-based novel heterocyclic compounds were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes.	Nitrogen	16-24	butyrylcholinesterase	Homo sapiens	185-206
34783117-3	2022	The synthesized nitrogen-based novel heterocyclic compounds were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes.	Nitrogen	16-24	butyrylcholinesterase	Homo sapiens	208-212
32316396-7	2020	KEGG and pathway enrichment analyses of those urinary metabolites, and the Person"s correlation analyses among those urinary metabolites and bone status revealed that LF impacted on bone formation via regulatory comprehensive pathways including taurine and hypotaurine metabolism, arginine and proline metabolism, cyanoamino acid metabolism, nitrogen metabolism, nicotinate and nicotinamide metabolism, and fatty acid biosynthesis.	Nitrogen	342-350	lactotransferrin	Rattus norvegicus	167-169
34783117-4	2022	The synthesized nitrogen-based novel heterocyclic compounds showed IC50 values in the range of 2.69-7.01 against hCA I, 2.40-4.59 against hCA II, 0.81-1.32 microM against AChE, and 20.83-1.70 microM against BChE enzymes.	Nitrogen	16-24	butyrylcholinesterase	Homo sapiens	207-211
34783117-5	2022	On the contrary, nitrogen-based novel heterocyclic compounds demonstrated Ki values between 2.93 +- 0.59-8.61 +- 1.39 against hCA I, 2.05 +- 0.62-4.97 +- 0.95 against hCA II, 0.34 +- 0.02-0.92 +- 0.17 nM against AChE, and 0.50 +- 0.04-1.20 +- 0.16 microM against BChE enzymes.	Nitrogen	17-25	butyrylcholinesterase	Homo sapiens	263-267
1423830-8	1992	Quantitative differences in adduct formation between IQ and N-acetyl-IQ indicated that metabolic activation of these arylamines preferentially occurs by P4501A2-catalyzed N-hydroxylation followed by O-acetylation mediated through NAT1 and/or NAT2.	Nitrogen	60-61	N-acetyltransferase 1	Homo sapiens	230-234
1363120-3	1992	The urinary excretion of gamma-glutamyltranspeptidase (gamma-GTP) and N-acetyl-beta-D-glucosaminidase (NAG) remained high for at least 3 d after the injection of BSO (100 mg/kg) and DEM (0.5 ml/kg), with no effect on the blood urea nitrogen level.	Nitrogen	232-240	gamma-glutamyltransferase 1	Rattus norvegicus	25-53
1363120-3	1992	The urinary excretion of gamma-glutamyltranspeptidase (gamma-GTP) and N-acetyl-beta-D-glucosaminidase (NAG) remained high for at least 3 d after the injection of BSO (100 mg/kg) and DEM (0.5 ml/kg), with no effect on the blood urea nitrogen level.	Nitrogen	232-240	gamma-glutamyltransferase 1	Rattus norvegicus	55-64
34873473-2	2021	In this study, we revealed that fucosyltransferase 8 (FUT8), an enzyme that mediates the core fucosylation of N-linked glycosylation, is an important regulator of malignant characteristics in human glioma that acts by modifying the activities of both the HGF receptor (MET) and epidermal growth factor receptor (EGFR).	Nitrogen	110-111	SAFB like transcription modulator	Homo sapiens	269-272
32220210-3	2020	CTF-1 with a staggered AB stacking order (orange powder) obtained in the presence of a catalytic amount of superacid at 250  C was transformed to highly crystalline CTF-1 with an eclipsed AA stacking order (greenish powder) and surface area of 646 m2 g-1 through annealing at 350  C under nitrogen.	Nitrogen	289-297	cardiotrophin 1	Homo sapiens	0-5
34734627-0	2021	A Cytosolic Reductase Pathway is Required for Efficient N-Glycosylation of an STT3B-Dependent Acceptor Site.	Nitrogen	56-57	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	78-83
1323700-5	1992	Analyses of the UL4 amino acid sequence revealed domains characteristic of a membrane-bound glycoprotein and included potential signature sequences for (i) a signal sequence, (ii) two N-linked glycosylation sites, and (iii) four transmembrane domains.	Nitrogen	184-185	nuclear protein UL4	Human alphaherpesvirus 1	16-19
32220210-3	2020	CTF-1 with a staggered AB stacking order (orange powder) obtained in the presence of a catalytic amount of superacid at 250  C was transformed to highly crystalline CTF-1 with an eclipsed AA stacking order (greenish powder) and surface area of 646 m2 g-1 through annealing at 350  C under nitrogen.	Nitrogen	289-297	cardiotrophin 1	Homo sapiens	165-170
32202754-3	2020	As a proof of concept, heterostructured Au/CoP nanoparticles dispersed on nitrogen-doped carbon with unique porosity, denoted as Au/CoP@NC-3, are synthesized by thermal treatment of Au nanoparticle-incorporated ZIF-67 precursor.	Nitrogen	74-82	caspase recruitment domain family member 16	Homo sapiens	43-46
1325657-6	1992	The amino-terminal nitrogen atom of the peptide forms a hydrogen bond with the hydroxyl group of Tyr-171 of H-2Kb at one end of the groove, while the carboxyl-terminal oxygen forms a hydrogen bond with the hydroxyl group of Tyr-84 at the other end.	Nitrogen	19-27	histocompatibility 2, K1, K region	Mus musculus	108-113
34750871-0	2022	Decoupling Complex Multi-Length-Scale Morphology in Non-Fullerene Photovoltaics with Nitrogen K-Edge Resonant Soft X-Ray Scattering.	Nitrogen	85-93	POC1 centriolar protein A	Homo sapiens	110-114
34750871-8	2022	Nitrogen is common in organic semiconductors and other soft materials, and the strong and directional N 1 pi* resonances make NK-RSoXS a powerful tool to uncover the mesoscale complexity and open opportunities to understand heterogeneous systems.	Nitrogen	0-8	POC1 centriolar protein A	Homo sapiens	55-59
34776611-6	2021	Single gas permeation data show that the permeability decreases with increasing molecular order while the ideal gas selectivity of He and CO2 over N2 increases tremendously (36-fold for He/N2 and 21-fold for CO2/N2) when going from randomly ordered to the highly ordered smectic C morphology.	Nitrogen	147-149	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	7-10
1444331-9	1992	Two crucial problems remaining to be solved with respect to cell cycle control are the nature of the connection between the RAS-adenylate cyclase pathway and nitrogen-source induced progression over the nutrient-starvation site of "start" and second the nature of the downstream processes linking the RAS-adenylate cyclase pathway to Cyclin/CDC28 controlled progression over the pheromone site of "start".	Nitrogen	158-166	cyclin-dependent serine/threonine-protein kinase CDC28	Saccharomyces cerevisiae S288C	341-346
1640266-7	1992	Somatotropin treatment increased the biological value of absorbed N, which was consistent with reductions in plasma urea nitrogen.	Nitrogen	66-67	somatotropin	Bos taurus	0-12
1640266-7	1992	Somatotropin treatment increased the biological value of absorbed N, which was consistent with reductions in plasma urea nitrogen.	Nitrogen	121-129	somatotropin	Bos taurus	0-12
34776611-6	2021	Single gas permeation data show that the permeability decreases with increasing molecular order while the ideal gas selectivity of He and CO2 over N2 increases tremendously (36-fold for He/N2 and 21-fold for CO2/N2) when going from randomly ordered to the highly ordered smectic C morphology.	Nitrogen	147-149	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	112-115
34776611-6	2021	Single gas permeation data show that the permeability decreases with increasing molecular order while the ideal gas selectivity of He and CO2 over N2 increases tremendously (36-fold for He/N2 and 21-fold for CO2/N2) when going from randomly ordered to the highly ordered smectic C morphology.	Nitrogen	147-149	complement C2	Homo sapiens	208-214
34776611-6	2021	Single gas permeation data show that the permeability decreases with increasing molecular order while the ideal gas selectivity of He and CO2 over N2 increases tremendously (36-fold for He/N2 and 21-fold for CO2/N2) when going from randomly ordered to the highly ordered smectic C morphology.	Nitrogen	189-191	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	7-10
34776611-6	2021	Single gas permeation data show that the permeability decreases with increasing molecular order while the ideal gas selectivity of He and CO2 over N2 increases tremendously (36-fold for He/N2 and 21-fold for CO2/N2) when going from randomly ordered to the highly ordered smectic C morphology.	Nitrogen	189-191	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	112-115
34858392-10	2021	Pearson and Spearman analyses revealed that serum resistin was positively correlated with CAP severity scores, white blood cells, urea nitrogen, creatinine, and inflammatory cytokines among CAP patients.	Nitrogen	135-143	resistin	Homo sapiens	50-58
1420598-9	1992	This study demonstrates that glycosylation of the extracellular domain of the IL-1RtI is due to N-linked carbohydrates, that the degree of glycosylation can vary in cells of different lineage, and that this N-linked glycosylation appears to be essential for optimal binding and activity of IL-1 to its type I receptor.	Nitrogen	96-97	interleukin 1 alpha	Homo sapiens	78-82
32087767-3	2020	With the use of a small interfering RNA (siRNA)-mediated approach for selective downregulation of the four Arg/N-degron-dependent ubiquitin ligases, UBR1, UBR2, UBR4, and UBR5, we demonstrated decreased cell migration and proliferation and increased spontaneous apoptosis in cancer cells.	Nitrogen	37-38	ubiquitin protein ligase E3 component n-recognin 4	Mus musculus	161-165
1628616-8	1992	The OCH1 protein was detected in yeast membrane fractions as four forms of 58-66 kDa, which correspond to the size of a glycoprotein containing four N-linked sugar chains the length of which is almost the same or slightly larger than the inner core (Man8GlcNAc2) formed in the endoplasmic reticulum (ER).	Nitrogen	149-150	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	4-8
34625256-2	2021	The development and progression of prostate cancer is not completely understood yet at molecular level, but it has been reported that changes in the N-glycosylation of prostate-specific antigen (PSA) occur during tumor genesis.	Nitrogen	149-150	kallikrein related peptidase 3	Homo sapiens	168-193
34625256-2	2021	The development and progression of prostate cancer is not completely understood yet at molecular level, but it has been reported that changes in the N-glycosylation of prostate-specific antigen (PSA) occur during tumor genesis.	Nitrogen	149-150	kallikrein related peptidase 3	Homo sapiens	195-198
32309747-1	2020	We have demonstrated the synthesis, characterization, and application of nitrogen-doped red-emitting carbon dots (NRCDs) for dual sensing of indium (In3+) and palladium (Pd2+) in water.	Nitrogen	73-81	PAF1 homolog, Paf1/RNA polymerase II complex component	Homo sapiens	170-173
34617306-2	2021	However, there is substantial variability in the T-N relationship - manifested in higher or lower atrophy than expected for level of tau in a given brain region.	Nitrogen	51-52	microtubule associated protein tau	Homo sapiens	133-136
1610817-3	1992	The guanidinium NH2 nitrogen of Arg 44 forms one hydrogen bond to the imide nitrogen and a second to the carbonyl oxygen of Pro 66 in wild-type DHFR.	Nitrogen	20-28	Dihydrofolate reductase	Escherichia coli	144-148
1535661-6	1992	It was shown that hydrophobic interactions of N-4 substituents of 1-arylpiperazines significantly contribute to their 5-HT1A affinity.	Nitrogen	46-47	5-hydroxytryptamine receptor 1A	Homo sapiens	118-124
31623019-3	2020	Among these cofactors, thioredoxin stands out as the most important ASK1 inhibitor, but only the reduced form of thioredoxin inhibits ASK1 by direct binding to its N-terminal domain.	Nitrogen	164-165	thioredoxin	Homo sapiens	113-124
34358989-5	2021	The results indicate sea salt is a better trigger for treating wastewater (nearly 100% total nitrogen and total phosphorus removal) and producing high-quality biodiesel (330 mg/L d).	Nitrogen	93-101	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	21-24
1600939-5	1992	In addition, in vitro N-glycosylation of the acceptor peptide Tyr-Asn-Leu-Thr-Ser-Val using microsomal membranes from WBP1 depleted cells is reduced as compared with membranes from wild-type cells.	Nitrogen	22-23	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	118-122
31623019-3	2020	Among these cofactors, thioredoxin stands out as the most important ASK1 inhibitor, but only the reduced form of thioredoxin inhibits ASK1 by direct binding to its N-terminal domain.	Nitrogen	164-165	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	134-138
31623019-7	2020	Our data reveal that the N-terminal domain of ASK1 adopts a fold resembling the thioredoxin structure while retaining substantial conformational plasticity at the thioredoxin-binding interface.	Nitrogen	25-26	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	46-50
31623019-7	2020	Our data reveal that the N-terminal domain of ASK1 adopts a fold resembling the thioredoxin structure while retaining substantial conformational plasticity at the thioredoxin-binding interface.	Nitrogen	25-26	thioredoxin	Homo sapiens	80-91
34560560-8	2021	Among those, two non-natural variants with N-methylated Leu3 (MeLeu3) and a reduced amide bond between Pro2 and Leu3 (rLeu3), respectively, showed resistance to DPP4 truncation but decreased CXCR3 signaling and chemotactic activity.	Nitrogen	43-44	dipeptidylpeptidase 4	Mus musculus	161-165
31623019-7	2020	Our data reveal that the N-terminal domain of ASK1 adopts a fold resembling the thioredoxin structure while retaining substantial conformational plasticity at the thioredoxin-binding interface.	Nitrogen	25-26	thioredoxin	Homo sapiens	163-174
34560560-8	2021	Among those, two non-natural variants with N-methylated Leu3 (MeLeu3) and a reduced amide bond between Pro2 and Leu3 (rLeu3), respectively, showed resistance to DPP4 truncation but decreased CXCR3 signaling and chemotactic activity.	Nitrogen	43-44	chemokine (C-X-C motif) receptor 3	Mus musculus	191-196
1605851-2	1992	The cDNA sequence of hPC1 encodes a protein containing 753 amino acids and potentially two N-glycosylation sites, one carboxy-terminal amidation site, a cAMP-dependent protein kinase Ser phosphorylation site, a tyrosine kinase phosphorylation site, and an ArgGlyAsp (RGD) sequence.	Nitrogen	6-7	proprotein convertase subtilisin/kexin type 1	Homo sapiens	21-25
1593873-11	1992	Mean daily nitrogen balance during treatment was negative in the rats receiving TBP (-14.5 +/- 20.1 mg +/- SEM) while remaining highly positive in the rats receiving NTBP (110.7 +/- 19.3, P less than 0.002).	Nitrogen	11-19	TATA box binding protein	Rattus norvegicus	80-83
16668807-1	1992	We previously showed that the selective accumulation of phosphoenolpyruvate carboxylase (PEPC) in photosynthetically maturing maize (Zea mays L.) leaf cells induced by nitrate supply to nitrogen-starved plants was primarily a consequence of the level of its mRNA (B Sugiharto, K Miyata, H Nakamoto, H Sasakawa, T Sugiyama [1990] Plant Physiol 92: 963-969).	Nitrogen	186-194	MLO-like protein 4	Zea mays	56-87
16668807-1	1992	We previously showed that the selective accumulation of phosphoenolpyruvate carboxylase (PEPC) in photosynthetically maturing maize (Zea mays L.) leaf cells induced by nitrate supply to nitrogen-starved plants was primarily a consequence of the level of its mRNA (B Sugiharto, K Miyata, H Nakamoto, H Sasakawa, T Sugiyama [1990] Plant Physiol 92: 963-969).	Nitrogen	186-194	MLO-like protein 4	Zea mays	89-93
16668807-2	1992	To determine the specificity of inorganic nitrogen sources for the regulation of PEPC gene expression, nitrate (16 millimolar) or ammonium (6 millimolar) was supplied to plants grown previously in low nitrate (0.8 millimolar), and changes in the level of PEPC and its mRNA were measured in the basal region of the youngest, fully developed leaves of plants during recovery from nitrogen stress.	Nitrogen	42-50	MLO-like protein 4	Zea mays	81-85
16668807-3	1992	The exogenous supply of nitrogen selectively increased the levels of protein and mRNA for PEPC.	Nitrogen	24-32	MLO-like protein 4	Zea mays	90-94
34636989-5	2021	We also verified the identified XBP1-dependent genes with specific silencing of this transcription factor during pharmacological ER stress induction with both an N-linked glycosylation inhibitor (tunicamycin) and a non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) (thapsigargin).	Nitrogen	162-163	X-box binding protein 1	Homo sapiens	32-36
34285372-2	2021	Activation of the nociceptin opioid peptide (NOP) receptor by its endogenous ligand Nociceptin/Orphanin FQ (N/OFQ) attenuates alcohol drinking and relapse in rodents, suggesting that NOP agonists may be efficacious in treating AUD.	Nitrogen	108-109	prepronociceptin	Rattus norvegicus	84-94
34285372-2	2021	Activation of the nociceptin opioid peptide (NOP) receptor by its endogenous ligand Nociceptin/Orphanin FQ (N/OFQ) attenuates alcohol drinking and relapse in rodents, suggesting that NOP agonists may be efficacious in treating AUD.	Nitrogen	108-109	prepronociceptin	Rattus norvegicus	95-106
16668807-5	1992	The accumulation of PEPC during nitrogen recovery increased in parallel with the increase in the activity of glutamine synthetase and/or ferredoxin-dependent glutamate synthase.	Nitrogen	32-40	MLO-like protein 4	Zea mays	20-24
16668807-7	1992	The administration of glutamine (12 millimolar) to nitrogen-starved plants increased the steady-state level of PEPC mRNA 7 hours after administration, whereas 12 millimolar glutamate decreased the level of PEPC mRNA.	Nitrogen	51-59	MLO-like protein 4	Zea mays	111-115
34620427-4	2021	Here, we found that PERK13 was transcriptionally responsive to Pi, nitrogen, and iron deficiencies.	Nitrogen	67-75	root hair specific 10	Arabidopsis thaliana	20-26
31812422-4	2020	The Mox/N-CNT nanocatalysts were thoroughly characterized via TEM, FE-SEM, XPS, N2 adsorption/desorption, and XRD techniques.	Nitrogen	8-9	monooxygenase DBH like 1	Homo sapiens	4-7
34620427-5	2021	Loss of PERK13 function (perk13) enhanced root hair growth under Pi/nitrogen limitation.	Nitrogen	68-76	root hair specific 10	Arabidopsis thaliana	8-14
34620427-5	2021	Loss of PERK13 function (perk13) enhanced root hair growth under Pi/nitrogen limitation.	Nitrogen	68-76	root hair specific 10	Arabidopsis thaliana	25-31
34745128-0	2021	Sequential Analysis of the N/O-Glycosylation of Heavily Glycosylated HIV-1 gp120 Using EThcD-sceHCD-MS/MS.	Nitrogen	27-28	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	75-80
16668807-8	1992	The results indicate that glutamine and/or its metabolite(s) can be a positive control on the nitrogen-dependent regulation of PEPC gene expression in maize leaf cells.	Nitrogen	94-102	MLO-like protein 4	Zea mays	127-131
1379482-1	1992	Molecular modeling techniques were used to derive a predictive model for substrates of cytochrome P450 2D6, an isozyme known to metabolize only compounds with one or more basic nitrogen atoms.	Nitrogen	177-185	cytochrome P450 2D6	Homo sapiens	87-106
31812422-4	2020	The Mox/N-CNT nanocatalysts were thoroughly characterized via TEM, FE-SEM, XPS, N2 adsorption/desorption, and XRD techniques.	Nitrogen	80-82	monooxygenase DBH like 1	Homo sapiens	4-7
34745128-6	2021	Finally, eighteen N-glycosites and five O-glycosites with attached glycans were assigned unambiguously from heavily glycosylated gp120.	Nitrogen	18-19	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	129-134
31812422-6	2020	The catalytic experiments on Mox/N-CNT were performed in temperature range of 190-230  C in which the feed gas was composed of 3000 ppm H2S and 1500 ppm O2.	Nitrogen	33-34	monooxygenase DBH like 1	Homo sapiens	29-32
34636529-5	2021	The chemical states of the K-In-Se phase, which have a beneficial effect on the solar-cell performance owing to the formation of durable and improved p-n junctions, are formed only at a KF PDT process time of 50 s. We derived band alignments from the XPS depth profiles by extracting the conduction- and valence-band offsets, and we used optical-pump-THz-probe spectroscopy to measure the ultrafast photocarrier lifetimes related to the defect states following KF PDT.	Nitrogen	152-153	arylformamidase	Homo sapiens	461-463
31812422-7	2020	The results showed that the Mox/N-CNT samples were highly active at all considered temperatures providing the H2S conversion of almost 100% from which almost no H2S was emitted.	Nitrogen	32-33	monooxygenase DBH like 1	Homo sapiens	28-31
1347768-3	1992	Upstream analysis of the gene using lacZ fusions has verified transcriptional control of the gene and has identified a nitrogen upstream activation sequence which is required for the increased transcription of GLN1 seen when glutamine is replaced by glutamate as the nitrogen source.	Nitrogen	119-127	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	210-214
1347768-3	1992	Upstream analysis of the gene using lacZ fusions has verified transcriptional control of the gene and has identified a nitrogen upstream activation sequence which is required for the increased transcription of GLN1 seen when glutamine is replaced by glutamate as the nitrogen source.	Nitrogen	267-275	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	210-214
31982140-3	2020	Dual-specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, has been reported to negatively modulate the mitogen-activated protein kinases (MAPKs) signaling, and it has never been investigated in NAFLD progression.	Nitrogen	50-51	dual specificity phosphatase 16	Mus musculus	0-31
34834161-9	2021	These findings suggest that Fab N-glycosites have higher accessibility to enzymes responsible for glycan maturation.	Nitrogen	32-33	FA complementation group B	Homo sapiens	28-31
31982140-3	2020	Dual-specificity phosphatase 16 (DUSP16), a c-Jun N-terminal kinase-specific phosphatase, has been reported to negatively modulate the mitogen-activated protein kinases (MAPKs) signaling, and it has never been investigated in NAFLD progression.	Nitrogen	50-51	dual specificity phosphatase 16	Mus musculus	33-39
32218144-4	2020	For NGr-1 and NGr-2, the nitrogen concentration obtained from elemental analysis was around 6.36 wt%.	Nitrogen	25-33	reticulon 4 receptor like 2	Homo sapiens	14-19
34684852-3	2021	The two pyrazolyl ligands in 1 coordinate with the nitrogen atoms to complete the Cu coordination sphere, resulting in a five-coordinated geometry-away from idealized trigonal bipyramidal and square pyramidal geometries-which can better be described as distorted square pyramidal, as measured by the tau and chi structural parameters.	Nitrogen	51-59	microtubule associated protein tau	Homo sapiens	300-303
1569370-19	1992	The putative lipid-binding domains of LPL and HL, the disulfide-bridging cysteine residues, catalytic residues, and N-linked glycosylation sites of LPL, HL, and PL all lie within regions having a CI of 0.8 or higher.	Nitrogen	116-117	lipoprotein lipase	Homo sapiens	148-151
16668656-5	1992	Conversely, inactivation of nitrate reductase by tungstate treatment in nitrate, nitrite, or nitrogen-free media made wild-type cells respond like nitrate reductase-deficient mutants with respect to the expression of nitrite uptake and nitrite reductase activities.	Nitrogen	93-101	uncharacterized protein	Chlamydomonas reinhardtii	28-45
1729223-0	1992	Nitrogen catabolite repression of arginase (CAR1) expression in Saccharomyces cerevisiae is derived from regulated inducer exclusion.	Nitrogen	0-8	arginase	Saccharomyces cerevisiae S288C	44-48
1819700-2	1991	Detailed quantitative hapten inhibition studies showed specificity for the acetyl group at C-2 of PAF, a requirement for the ether linkage at C-1 and some tolerance for substituents on the choline nitrogen.	Nitrogen	197-205	PCNA clamp associated factor	Homo sapiens	98-101
32210322-3	2020	This report examined the feasibility of degrading ciprofloxacin and sulfamethoxazole through photoelectrocatalytic oxidation using FTO-BiVO4/Ag2S with p-n heterojunction as anode.	Nitrogen	17-18	FTO alpha-ketoglutarate dependent dioxygenase	Homo sapiens	131-134
32258867-4	2020	Results show that mixing 75 wt % of DMF with 25 wt % GBL enhanced the membrane gas permeability toward hydrogen, methane, helium, carbon dioxide, and nitrogen.	Nitrogen	150-158	gastrin	Homo sapiens	79-82
1931884-4	1991	In the present study, secretion of PAI-1 by human umbilical vein endothelial cells (HUVEC) in culture was evaluated after incubation with N-LDL and ox-LDL.	Nitrogen	138-139	serpin family E member 1	Homo sapiens	35-40
1656067-5	1991	The env genes of CAEV-63 and CAEV-Co encode 28 conserved cysteines and 25 conserved potential N-linked glycosylation sites.	Nitrogen	94-95	envelope polyprotein;trans-regulatory splicing-like protein	Caprine arthritis encephalitis virus	4-7
31691474-6	2020	The experimental studies and DFT calculations reveal that the high performance of the Co@FLG is mainly attributed to its great O2 absorptivity endowed by the abundant Co-Nx and pyridinic-N in the FLG shell and the strong electron-donating ability from the Co ND core to the FLG shell to elevate the eg-orbital energy of Co(II) and lower the activation energy for breaking the O=O/O-O bonds.	Nitrogen	177-188	filaggrin	Homo sapiens	89-92
1885580-3	1991	In the present study, site-directed point mutations of the 5 conserved cysteine (Cys) residues and of the three potential N-linked glycosylation sites in the extracellular domain of the rat PRL receptor were constructed to assess their involvement in hormone binding.	Nitrogen	122-123	prolactin receptor	Rattus norvegicus	190-202
31691474-6	2020	The experimental studies and DFT calculations reveal that the high performance of the Co@FLG is mainly attributed to its great O2 absorptivity endowed by the abundant Co-Nx and pyridinic-N in the FLG shell and the strong electron-donating ability from the Co ND core to the FLG shell to elevate the eg-orbital energy of Co(II) and lower the activation energy for breaking the O=O/O-O bonds.	Nitrogen	177-188	filaggrin	Homo sapiens	196-199
31691474-6	2020	The experimental studies and DFT calculations reveal that the high performance of the Co@FLG is mainly attributed to its great O2 absorptivity endowed by the abundant Co-Nx and pyridinic-N in the FLG shell and the strong electron-donating ability from the Co ND core to the FLG shell to elevate the eg-orbital energy of Co(II) and lower the activation energy for breaking the O=O/O-O bonds.	Nitrogen	177-188	filaggrin	Homo sapiens	196-199
32265964-0	2020	Nitrogen Depletion Blocks Growth Stimulation Driven by the Expression of Nitric Oxide Synthase in Tobacco.	Nitrogen	0-8	putative nitric oxide synthase	Nicotiana tabacum	73-94
1710892-2	1991	IGF-I at a dose of 1.05 or 1.08 mg/kg per day in two experiments increased body weight and nitrogen retention above those of vehicle-infused controls to about 30% of the improvement achieved with 25 or 30 units of insulin/kg per day, but only in the second experiment were the differences statistically significant (P less than 0.05).	Nitrogen	91-99	insulin-like growth factor 1	Rattus norvegicus	0-5
32009148-5	2020	Here we present the full-length structure of the Class 1 OLD nuclease from Thermus scotoductus (Ts) at 2.20 A resolution, which reveals a dimerization domain inserted into an N-terminal ABC ATPase fold and a C-terminal Toprim domain.	Nitrogen	175-176	nuclease	Escherichia coli	61-69
1878995-1	1991	The recessive hnm1 mutant allele is responsible for hyper-resistance to nitrogen mustard in Saccharomyces cerevisiae.	Nitrogen	72-80	Hnm1p	Saccharomyces cerevisiae S288C	14-18
1878995-5	1991	Sensitivity to nitrogen mustard of wild-type HNM1, but not of hnm1 mutants, depends on the choline content of the growth medium, with cells grown in choline-free medium exhibiting the highest sensitivity.	Nitrogen	15-23	Hnm1p	Saccharomyces cerevisiae S288C	45-49
32184390-3	2020	The fate of glutamine nitrogen is shifted from the anaplerotic pathway into the TCA cycle to nucleotide biosynthesis, with this shift being controlled by glutaminase (GLS1) and phosphoribosyl pyrophosphate amidotransferase (PPAT).	Nitrogen	22-30	glutaminase	Homo sapiens	167-171
2005641-10	1991	These results indicate that increased expression of ERCC1 and increased activity of 3-methyladenine-DNA glycosylase occur with the development of resistance to the nitrogen mustards in patients with CLL, suggesting a role for enhanced DNA repair in this process.	Nitrogen	164-172	ERCC excision repair 1, endonuclease non-catalytic subunit	Homo sapiens	52-57
31988244-4	2020	Here, using  expression of two plant AMTs (AtAMT1;2 and AMT2) in budding yeast, we found that systematic replacements in the conserved twin-histidine motif, a hallmark of most AMTs/Meps/Rhs, alter substrate recognition, transport capacities, the nitrogen (N)-isotope selection and selectivity against K+ AMT-specific differences were found for histidine variants.	Nitrogen	246-254	ammonium transporter 1;2	Arabidopsis thaliana	43-51
31988244-4	2020	Here, using  expression of two plant AMTs (AtAMT1;2 and AMT2) in budding yeast, we found that systematic replacements in the conserved twin-histidine motif, a hallmark of most AMTs/Meps/Rhs, alter substrate recognition, transport capacities, the nitrogen (N)-isotope selection and selectivity against K+ AMT-specific differences were found for histidine variants.	Nitrogen	256-257	ammonium transporter 1;2	Arabidopsis thaliana	43-51
1988041-13	1991	These chemical studies established that the active site of human milk BAL is located at serine-194, the N-glycosylation site is present at asparagine-187, the O-glycosylation region is in the 16 repeating units near the C-terminus, and the heparin binding domain is in the N-terminal region.	Nitrogen	104-105	carboxyl ester lipase	Homo sapiens	70-73
31853635-3	2020	Here, we show that soluble aggregates of alpha-synuclein and tau bind to plate-immobilized PrP in vitro and on mouse cortical neurons, and that this binding requires at least one of the same N-terminal sites at which soluble Abeta aggregates bind.	Nitrogen	191-192	synuclein, alpha	Mus musculus	41-56
2030176-0	1991	Effect of long-term bovine somatotropin (sometribove) treatment on nitrogen (protein) distribution in Jersey milk.	Nitrogen	67-75	somatotropin	Bos taurus	27-39
31916153-9	2020	Our analysis also found nitrogen-rich water and TSS in the rainy season as the driving factors of observed HCBs in the eutrophic Tri An Reservoir (TAR), which offer important solutions to the management of HCBs in the future.	Nitrogen	24-32	tRNA-Ile (anticodon AAT) 9-1	Homo sapiens	129-132
1886079-4	1991	To develop agents having enhanced potency and selectivity for the 5-HT1A site, several ring systems offering enhanced conformational rigidity which approximate the oxygen to nitrogen interatomic distances of 8-OH-DPAT and (to a lesser extent) 5-HT were synthesized.	Nitrogen	174-182	5-hydroxytryptamine receptor 1A	Homo sapiens	66-72
1702293-6	1990	TNF-BP contains 24 cysteine residues and three potential N-glycosylation sites and shows sequence homology to the extracellular portions of TNF-R p80 chain and nerve growth factor receptor.	Nitrogen	1-2	TNF receptor superfamily member 1A	Homo sapiens	140-145
1702293-6	1990	TNF-BP contains 24 cysteine residues and three potential N-glycosylation sites and shows sequence homology to the extracellular portions of TNF-R p80 chain and nerve growth factor receptor.	Nitrogen	1-2	nerve growth factor receptor	Homo sapiens	160-188
2247463-4	1990	Although bathoiodopsin produced at the temperature of liquid nitrogen or helium reverted to the original pigment (iodopsin) on warming (above -170 degrees C), the bathoiodopsin produced at physiological temperature decayed to all-trans-retinal and R-photopsin (the protein moiety of iodopsin) presumably through several intermediates.	Nitrogen	61-69	opsin 1 (cone pigments), long-wave-sensitive (color blindness, protan)	Gallus gallus	14-22
31433904-11	2020	CONCLUSIONS: Higher ratios of serum n-3 to n-6 PUFAs were associated with lower serum resistin levels.	Nitrogen	36-37	resistin	Homo sapiens	86-94
2175697-6	1990	Plasma thrombomodulin concentrations were positively correlated with the level of serum creatine, blood urea nitrogen, urinary albumin and urinary beta 2-microglobulin (P less than 0.001 for each), but not with fasting plasma glucose, hemoglobin A1c or fructosamine.	Nitrogen	109-117	thrombomodulin	Homo sapiens	7-21
31433904-11	2020	CONCLUSIONS: Higher ratios of serum n-3 to n-6 PUFAs were associated with lower serum resistin levels.	Nitrogen	43-44	resistin	Homo sapiens	86-94
1975578-2	1990	A yeast strain with a deletion-disruption allele of GDH2 which replaced the wild-type gene grew very poorly with glutamate as a nitrogen source, but growth improved significantly when the strain was also provided with adenine or other nitrogenous compounds whose biosynthesis requires glutamine.	Nitrogen	128-136	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	52-56
31658388-6	2020	The NMR solution structure of a fourth member of the DUF3349 superfamily, MAB_3403c, with 18 residues missing at the N-terminus, revealed a monomeric alpha-helical protein with a folding topology similar to the three C-terminal helices in the protomer of the MSMEG_1066 tetramer.	Nitrogen	4-5	MAB_3403c	Mycobacterium abscessus	74-83
31836139-7	2020	The positively charged residues (Lys 92, Arg 95 and Lys 96) located in the beta-alpha4 loop of the target RNA interface show high conformational flexibility, while three-helix bundles (alpha1-alpha3) of the N-domain involved in Csm2 binding exhibit a rotational shift.	Nitrogen	107-108	adrenoceptor alpha 1D	Homo sapiens	185-198
2328499-0	1990	Androgen-dependent renal microsomal cytochrome P-450 responsible for N-hydroxylation and mutagenic activation of 3-methoxy-4-aminoazobenzene in the BALB/c mouse.	Nitrogen	69-70	cytochrome P450, family 21, subfamily a, polypeptide 1	Mus musculus	36-52
31836139-7	2020	The positively charged residues (Lys 92, Arg 95 and Lys 96) located in the beta-alpha4 loop of the target RNA interface show high conformational flexibility, while three-helix bundles (alpha1-alpha3) of the N-domain involved in Csm2 binding exhibit a rotational shift.	Nitrogen	107-108	desmin	Homo sapiens	228-232
2319135-3	1990	The CD38 cDNA sequence predicts an unusual 30-kDa polypeptide with a short N-terminal cytoplasmic tail, and a carboxyl-terminal extracellular domain carrying the four potential N-linked glycosylation sites.	Nitrogen	11-12	CD38 molecule	Homo sapiens	4-8
31858971-3	2020	In this follow-up study, we provide evidence that the N-glycosylation on integrin beta1 subunit suppress cell growth by promoting its association with EGFR under fibronectin (FN)-coated conditions.	Nitrogen	54-55	fibronectin 1	Bos taurus	162-173
16667412-1	1990	We have utilized the cellular differentiation gradient of the developed, youngest leaf to examine the regulation by nitrogen of levels of phosphoenolpyruvate carboxylase (PEPCase), pyruvate orthophosphate dikinase (PPDK), and ribulose 1,5-bisphosphate carboxylase in maize (Zea mays L.).	Nitrogen	116-124	MLO-like protein 4	Zea mays	138-169
31858971-3	2020	In this follow-up study, we provide evidence that the N-glycosylation on integrin beta1 subunit suppress cell growth by promoting its association with EGFR under fibronectin (FN)-coated conditions.	Nitrogen	54-55	fibronectin 1	Bos taurus	175-177
32016190-2	2020	In this work, we developed a solvent-free gram-scale mechanochemical method for the preparation of nitrogen-doped graphene quantum dots (N-GQDs) with the highest solubility (31 mg mL-1) in water reported to date.	Nitrogen	99-107	L1 cell adhesion molecule	Mus musculus	180-184
2329007-6	1990	Second, the distinguishing polymorphism between mice of phenotype 1 and phenotypes 2 or 3 was due to the presence of an N-linked glycosylation site within the Tcrg-Cl gene segment, previously described for BALB.B and C57BL/6 Tcrg-Cl genes.	Nitrogen	120-121	T cell receptor gamma chain	Mus musculus	159-163
2329007-6	1990	Second, the distinguishing polymorphism between mice of phenotype 1 and phenotypes 2 or 3 was due to the presence of an N-linked glycosylation site within the Tcrg-Cl gene segment, previously described for BALB.B and C57BL/6 Tcrg-Cl genes.	Nitrogen	120-121	T cell receptor gamma chain	Mus musculus	225-229
32058968-7	2020	Meanwhile, the binding of SOMCL-16-171 and SOMCL-16-175 to Hsp90M was demonstrated to allosterically modulate the structure and function of Hsp90alpha"s N-terminal domain.	Nitrogen	153-154	heat shock protein 90 alpha family class A member 1	Homo sapiens	140-150
33766769-2	2021	In vitro study results showed that introducing a nitrogen atom around the indole moiety not only retained excellent binding affinity, but also led to significant functional switch at the mu opioid receptor (MOR).	Nitrogen	49-57	opioid receptor mu 1	Homo sapiens	187-205
33766769-2	2021	In vitro study results showed that introducing a nitrogen atom around the indole moiety not only retained excellent binding affinity, but also led to significant functional switch at the mu opioid receptor (MOR).	Nitrogen	49-57	opioid receptor mu 1	Homo sapiens	207-210
31899794-6	2020	We show that BMP6 binds the N-terminal domain of ERFE, and a polypeptide derived from the N-terminus of ERFE was sufficient to cause hepcidin suppression in Huh7 hepatoma cells and in wildtype mice.	Nitrogen	28-29	erythroferrone	Homo sapiens	49-53
34723019-6	2021	It was found that the addition of the nitrogen dopant improved the MSI by promoting electronic rearrangement from the metals" d- to s-orbitals for greater orbital overlap with the carbon support, shown with increased favorable adsorption.	Nitrogen	38-46	RB binding protein 4, chromatin remodeling factor	Homo sapiens	67-70
34742147-4	2022	When the background gas is pure nitrogen and a mixture of nitrogen and carbon dioxide, the recovery effect of this method on methane is both close to the theoretical value when the background gas is air.	Nitrogen	32-40	gastrin	Homo sapiens	20-23
31899794-6	2020	We show that BMP6 binds the N-terminal domain of ERFE, and a polypeptide derived from the N-terminus of ERFE was sufficient to cause hepcidin suppression in Huh7 hepatoma cells and in wildtype mice.	Nitrogen	90-91	erythroferrone	Homo sapiens	104-108
34742147-4	2022	When the background gas is pure nitrogen and a mixture of nitrogen and carbon dioxide, the recovery effect of this method on methane is both close to the theoretical value when the background gas is air.	Nitrogen	58-66	gastrin	Homo sapiens	20-23
34742147-4	2022	When the background gas is pure nitrogen and a mixture of nitrogen and carbon dioxide, the recovery effect of this method on methane is both close to the theoretical value when the background gas is air.	Nitrogen	58-66	gastrin	Homo sapiens	192-195
34962378-0	2022	MOF-on-MOF Strategy to Construct a Nitrogen-Doped Carbon-Incorporated CoP@Fe-CoP Core-Shelled Heterostructure for High-Performance Overall Water Splitting.	Nitrogen	35-43	caspase recruitment domain family member 16	Homo sapiens	70-73
34962378-0	2022	MOF-on-MOF Strategy to Construct a Nitrogen-Doped Carbon-Incorporated CoP@Fe-CoP Core-Shelled Heterostructure for High-Performance Overall Water Splitting.	Nitrogen	35-43	caspase recruitment domain family member 16	Homo sapiens	77-80
34962378-2	2022	Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA).	Nitrogen	20-28	caspase recruitment domain family member 16	Homo sapiens	55-58
34271449-4	2021	NO intensifies the stress-mitigating effect of Si, whereas in the case of Se, As, and Sb, the accumulation of NO or reactive nitrogen species contributes to toxicity.	Nitrogen	125-133	squalene epoxidase	Homo sapiens	74-76
34648192-5	2022	RESULTS: The experiments in supersomes revealed CYP1A2 as the major CYP for 4-MAA N-demethylation and 4-FAA formation with CYP2C19 and CYP2D6 contributing to N-demethylation.	Nitrogen	82-83	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	48-54
34962378-2	2022	Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA).	Nitrogen	20-28	caspase recruitment domain family member 16	Homo sapiens	62-65
34962378-2	2022	Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA).	Nitrogen	20-28	caspase recruitment domain family member 16	Homo sapiens	112-115
31899794-6	2020	We show that BMP6 binds the N-terminal domain of ERFE, and a polypeptide derived from the N-terminus of ERFE was sufficient to cause hepcidin suppression in Huh7 hepatoma cells and in wildtype mice.	Nitrogen	90-91	hepcidin antimicrobial peptide	Homo sapiens	133-141
34962378-2	2022	Herein, we prepared nitrogen-doped carbon-incorporated CoP@Fe-CoP core-shelled nanorod arrays grown on Ni foam (CoP@Fe-CoP/NC/NF) through phosphorization of ZIF-67@Co-Fe Prussian blue analogue (ZIF-67@CoFe-PBA).	Nitrogen	20-28	caspase recruitment domain family member 16	Homo sapiens	119-122
34765910-2	2021	In eukaryotes, target of rapamycin (TOR) is a central nutrient sensor, especially N, and a master-regulator of growth and development.	Nitrogen	82-83	Serine/threonine-protein kinase TOR	Zea mays	15-34
34765910-2	2021	In eukaryotes, target of rapamycin (TOR) is a central nutrient sensor, especially N, and a master-regulator of growth and development.	Nitrogen	82-83	Serine/threonine-protein kinase TOR	Zea mays	36-39
31899794-7	2020	Anti-ERFE antibodies targeting the N-terminal domain prevented hepcidin suppression in ERFE-treated Huh7 cells and in EPO-treated mice.	Nitrogen	35-36	erythroferrone	Homo sapiens	5-9
31899794-7	2020	Anti-ERFE antibodies targeting the N-terminal domain prevented hepcidin suppression in ERFE-treated Huh7 cells and in EPO-treated mice.	Nitrogen	35-36	hepcidin antimicrobial peptide	Homo sapiens	63-71
34500150-3	2022	The widespread dispersion of ultrafine Pd NPs was a result of the abundant high nitrogen-content triazine groups of CTF-1 that endowed the catalyst Pd@CTF-1 with high catalytic activity.	Nitrogen	80-88	cardiotrophin 1	Homo sapiens	116-121
34500150-3	2022	The widespread dispersion of ultrafine Pd NPs was a result of the abundant high nitrogen-content triazine groups of CTF-1 that endowed the catalyst Pd@CTF-1 with high catalytic activity.	Nitrogen	80-88	cardiotrophin 1	Homo sapiens	151-156
31899794-7	2020	Anti-ERFE antibodies targeting the N-terminal domain prevented hepcidin suppression in ERFE-treated Huh7 cells and in EPO-treated mice.	Nitrogen	35-36	erythroferrone	Homo sapiens	87-91
31899794-9	2020	In summary, we demonstrate that ERFE binds BMP6 directly and with high affinity, and that antibodies targeting the N-terminal domain of ERFE that prevent ERFE-BMP6 interactions constitute a potential therapeutic tool for iron-loading anemias.	Nitrogen	115-116	bone morphogenetic protein 6	Mus musculus	159-163
34570486-7	2021	Spun fibers retained the adsorptive properties of CC3 powders, as confirmed by CO2 and N2 physisorption and TGA, reaching upward of 60 wt % adsorbent loading, whereas the pelletized CC3 counterparts suffered significant losses in textural properties.	Nitrogen	87-89	C-C motif chemokine ligand 14	Homo sapiens	50-53
32075754-4	2020	We show that the N terminus of Sen1 is both sufficient and necessary for replisome association and that it binds to the replisome via the components Ctf4 and Mrc1.	Nitrogen	17-18	WD repeat and HMG-box DNA binding protein 1	Homo sapiens	149-153
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	356-364	solute carrier family 26 member 9	Ovis aries	265-272
34786856-0	2022	Recent Developments in the Chemistry of Pn(I) (Pn = N, P, As, Sb, Bi) Cations.	Nitrogen	52-53	serpin family E member 2	Homo sapiens	40-45
34786856-1	2022	The Group 15 Pn(I) cations (Pn = N, P, As, Sb and Bi), which are isoelectronic with the donor-stabilized carbones, have emerged recently.	Nitrogen	33-34	serpin family E member 2	Homo sapiens	13-18
31951373-1	2020	Here, we reported that sulfur vacancy-rich O-doped 1T-MoS2 nanosheets (denoted as SV-1T-MoS2) can surpass the activity of Pt as cocatalysts to assist in the photocatalytic nitrogen fixation of CdS nanorods.	Nitrogen	172-180	CDP-diacylglycerol synthase 1	Homo sapiens	193-196
34352515-5	2021	Compared with those incubated with NH4+, juice sacs under nitrogen deficiency exhibited enhanced flux through phosphoenolpyruvate carboxykinase (PEPCK) and accelerated consumption of citrate, while the other two TCA cycle efflux points, through malic enzyme (ME) and glutamate dehydrogenase (GDH), were both repressed.	Nitrogen	58-66	glutamate dehydrogenase 1	Homo sapiens	267-290
34352515-5	2021	Compared with those incubated with NH4+, juice sacs under nitrogen deficiency exhibited enhanced flux through phosphoenolpyruvate carboxykinase (PEPCK) and accelerated consumption of citrate, while the other two TCA cycle efflux points, through malic enzyme (ME) and glutamate dehydrogenase (GDH), were both repressed.	Nitrogen	58-66	glutamate dehydrogenase 1	Homo sapiens	292-295
34619534-0	2022	Transcriptomic evidences for microbial carbon and nitrogen cycles in the deoxygenated seawaters of Bohai Sea.	Nitrogen	50-58	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	105-108
31951373-3	2020	Consequently, the optimized 30 wt % SV-1T-MoS2-/CdS composites exhibit an outstanding nitrogen fixation rate of 8220.83 mumol L-1 h-1 g-1 and long-term stability under simulated solar light irradiation, significantly higher than pure CdS nanorods, CdS-Pt (0.1 wt %), and 30 wt % 1T-MoS2/CdS composites.	Nitrogen	86-94	CDP-diacylglycerol synthase 1	Homo sapiens	48-51
34798465-8	2022	Consistently, the anthocyanin content in pap1-D/35S::PIF4 and 35S::PAP1/35S::PIF4 seedlings was markedly lower than that in pap1-D and 35S::PAP1 under 6-BA, MeJA, -N, and NaCl stresses, implying that overexpression of PIF4 suppresses anthocyanin accumulation in pap1-D and 35S::PAP1.	Nitrogen	164-165	phytochrome interacting factor 4	Arabidopsis thaliana	77-81
34798465-8	2022	Consistently, the anthocyanin content in pap1-D/35S::PIF4 and 35S::PAP1/35S::PIF4 seedlings was markedly lower than that in pap1-D and 35S::PAP1 under 6-BA, MeJA, -N, and NaCl stresses, implying that overexpression of PIF4 suppresses anthocyanin accumulation in pap1-D and 35S::PAP1.	Nitrogen	164-165	phytochrome interacting factor 4	Arabidopsis thaliana	218-222
34352515-6	2021	Consistent with the estimated fluxes, the expression of PEPCK1 was upregulated under nitrogen deficiency, while that of GDH1, GDH2, NAD-ME1 and NADP-ME2 were all repressed.	Nitrogen	85-93	phosphoenolpyruvate carboxykinase 1	Homo sapiens	56-62
34352515-7	2021	Thus, we propose that PEPCK1 contributes to citrate degradation under nitrogen limitation.	Nitrogen	70-78	phosphoenolpyruvate carboxykinase 1	Homo sapiens	22-28
34638886-3	2021	We also present examples of the PPARalpha-specific immunomodulatory functions during parasitic, bacterial, and viral infections, as well as approach several issues associated with innate immunity processes, such as the production of reactive nitrogen and oxygen species, phagocytosis, and the effector functions of macrophages, innate lymphoid cells, and mast cells.	Nitrogen	242-250	peroxisome proliferator activated receptor alpha	Homo sapiens	32-41
34646384-6	2021	A survival screen, to determine if glycan remodeling enzymes are redundant, identified MGAT1 and NGLY1, essential components of the N-glycosylation/degradation pathway, as highly relevant within this in vitro screening.	Nitrogen	132-133	N-glycanase 1	Homo sapiens	97-102
32050972-11	2020	RESULTS: DCX undergoes nucleocytoplasmic movement via the RanGTPase signaling pathway with an NLS located on the N-terminus between serine47-tyrosine70.	Nitrogen	94-95	doublecortin	Mus musculus	9-12
34603392-10	2021	Importantly, COG4-G516R cells demonstrated increased HPA-647 binding to the plasma membrane glycoconjugates, while COG4-R729W cells revealed high GNL-647 binding, indicating specific defects in O- and N-glycosylation.	Nitrogen	201-202	component of oligomeric golgi complex 4	Homo sapiens	13-17
34943103-5	2021	The (GT)n/(TA)n dinucleotide variations in HMOX1/UGT1A1 gene promoters, respectively, were analyzed by fragment analysis.	Nitrogen	8-9	heme oxygenase 1	Homo sapiens	43-48
34571419-8	2021	In addition, the SUVA254 value and C/C ratio increased, while the E4/E6 ratio reduced after N addition in surface water and soil pore water, indicating increases in DOM aromaticity and humification.	Nitrogen	92-93	ubiquitination factor E4A	Homo sapiens	66-71
31793779-1	2020	Here, we describe a convergent synthesis of human granulocyte-macrophage colony-stimulating factor (hGM-CSF) harboring both O- and N-glycosylation sites using a Se-auxiliary-mediated ligation protocol together with native chemical ligation methodology.	Nitrogen	131-132	colony stimulating factor 2	Homo sapiens	50-98
31793779-1	2020	Here, we describe a convergent synthesis of human granulocyte-macrophage colony-stimulating factor (hGM-CSF) harboring both O- and N-glycosylation sites using a Se-auxiliary-mediated ligation protocol together with native chemical ligation methodology.	Nitrogen	131-132	colony stimulating factor 2	Homo sapiens	100-107
34966404-8	2021	An increase was observed in some key enzymatic activities and transcription involved in nitrogen metabolism, such as that of nitrate reductase, nitrite reductase, glutamate synthase, and glutamine synthetase, in melatonin-treated, drought-stressed maize.	Nitrogen	88-96	nitrate reductase [NADH] 1	Zea mays	125-142
31793779-2	2020	The robust and rapid Se-mediated ligation enables assembly of the N-terminus of hGM-CSF in just 4 h, which is significantly faster than the traditional ligation/desulfurization method.	Nitrogen	66-67	colony stimulating factor 2	Homo sapiens	80-87
34526532-2	2021	This study evaluates the role of endothelial nitric oxide synthase (eNOS) in the expression of the ventilatory responses during and following a hypoxic gas challenge (HXC, 10% O2, 90% N2) in freely moving male and female wild-type (WT) C57BL6 and eNOS knock-out (eNOS-/-) mice.	Nitrogen	184-186	nitric oxide synthase 3, endothelial cell	Mus musculus	33-66
34526532-2	2021	This study evaluates the role of endothelial nitric oxide synthase (eNOS) in the expression of the ventilatory responses during and following a hypoxic gas challenge (HXC, 10% O2, 90% N2) in freely moving male and female wild-type (WT) C57BL6 and eNOS knock-out (eNOS-/-) mice.	Nitrogen	184-186	nitric oxide synthase 3, endothelial cell	Mus musculus	68-72
31845908-3	2020	We performed multistep biochemical, structural, and computational experiments to define a spherical 24-monomer complex composed of 12 HSP27 dimers with a phosphorylation pocket flanked by serine residues between their N-terminal domains.	Nitrogen	218-219	heat shock protein family B (small) member 1	Homo sapiens	134-139
34612280-5	2021	Microhydration suppresses fragmentation of both molecules, however in bromothiophenol, the Br- channel remains intense and Br(H2O)n- hydrated fragment clusters are observed.	Nitrogen	130-131	chromosome 12 open reading frame 73	Homo sapiens	123-125
34812037-0	2021	Tuning the Electronic Structure of the CoP/Ni2P Nanostructure by Nitrogen Doping for an Efficient Hydrogen Evolution Reaction in Alkaline Media.	Nitrogen	65-73	caspase recruitment domain family member 16	Homo sapiens	39-42
34812037-2	2021	Herein, a self-supported and nitrogen-doped hybrid CoP/Ni2P was synthesized through a simple two-step hydrothermal process followed by low-temperature phosphorization and nitridation (N-CoP/Ni2P@NF).	Nitrogen	29-37	caspase recruitment domain family member 16	Homo sapiens	51-54
34812037-2	2021	Herein, a self-supported and nitrogen-doped hybrid CoP/Ni2P was synthesized through a simple two-step hydrothermal process followed by low-temperature phosphorization and nitridation (N-CoP/Ni2P@NF).	Nitrogen	29-37	caspase recruitment domain family member 16	Homo sapiens	186-189
34812037-3	2021	Both experimental and density functional theory calculation results suggest that nitrogen doping can tune the electrical structure of the CoP/Ni2P heterostructure and thus optimize the free energy of adsorbed H on the surface of N-CoP/Ni2P@NF and accelerate the electronic transport activity.	Nitrogen	81-89	caspase recruitment domain family member 16	Homo sapiens	138-141
34812037-3	2021	Both experimental and density functional theory calculation results suggest that nitrogen doping can tune the electrical structure of the CoP/Ni2P heterostructure and thus optimize the free energy of adsorbed H on the surface of N-CoP/Ni2P@NF and accelerate the electronic transport activity.	Nitrogen	81-89	caspase recruitment domain family member 16	Homo sapiens	231-234
31672543-4	2020	TRP3 was labeled with TOAC at the N-terminus (prior to V1, TOAC0-TRP3) or internally (replacing P5, TOAC5-TRP3).	Nitrogen	34-35	tRNA-Pro (anticodon TGG) 3-1	Homo sapiens	0-4
34522617-2	2021	Sodium 4-phenylbutyrate (NaPB), a standard adjunctive therapy for UCDs, generates an alternative pathway of nitrogen deposition through glutamine consumption.	Nitrogen	108-116	NSF attachment protein beta	Homo sapiens	25-29
34789879-2	2021	In yeast, Ubr1-a single-subunit E3 ligase-is responsible for the Arg/N-degron pathway2.	Nitrogen	69-70	E3 ubiquitin-protein ligase UBR1	Saccharomyces cerevisiae S288C	10-14
31672543-10	2020	While the mechanism of action of TRP3 was impacted to some extent by TOAC labeling at the N-terminus, it did change upon replacement of P5 by TOAC.	Nitrogen	90-91	tRNA-Pro (anticodon TGG) 3-1	Homo sapiens	33-37
34808183-8	2022	The three MPs affected NH4+ metabolism by changing the abundance of a NH2OH-forming gene (amoA) and an organic nitrogen-forming gene (gdh), as well as the abundances of Thiobacillus, Bradyrhizobium, Anaeromyxobacter, Geobacter, and Desulfobacca.	Nitrogen	111-119	glutamate dehydrogenase 1	Homo sapiens	134-137
34476615-7	2021	Thus, the Nb2C-SH QD-based SPR aptasensor had low limit of detection (LOD) of 4.9 pg mL-1 toward N-gene within the concentration range 0.05 to 100 ng mL-1.	Nitrogen	97-98	L1 cell adhesion molecule	Mus musculus	85-89
34117813-5	2021	GnT-V medicated N-glycosylation on VE-cadherin regulates the dissociation of VE-cadherin/beta-catenin complex to modulate the monocyte adhesion, but GnT-V overexpression can not rescue monocyte adhesion induced by IL-1beta.	Nitrogen	16-17	catenin beta 1	Homo sapiens	89-101
34118782-4	2021	Compared to other electron acceptors used in anaerobic respiration (e.g. N, S, Fe, Mn, and As), Se is one of the few elements whose end product is solid.	Nitrogen	73-74	squalene epoxidase	Homo sapiens	96-98
34730347-2	2021	Here we synthesized a series of supported Pt1 SACs by depositing Pt atoms onto the pretuned anchoring sites on nitrogen-doped carbon using atomic layer deposition.	Nitrogen	111-119	zinc finger protein 77	Homo sapiens	42-45
34730347-3	2021	In hydrogenation of para-chloronitrobenzene, the Pt1 SAC with a higher CN about four but less pyridinic nitrogen (Npyri) content exhibits a remarkably high activity along with superior recyclability compared to those with lower CNs and more Npyri.	Nitrogen	104-112	zinc finger protein 77	Homo sapiens	49-52
31874826-3	2020	Here, we focused on the N-terminal domain (ND) of follistatin (Fst) that interacts with the type I receptor binding site of myostatin.	Nitrogen	24-25	myostatin	Mus musculus	124-133
34380095-0	2021	Budget of riverine nitrogen over the East China Sea shelf.	Nitrogen	19-27	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	48-51
34380095-1	2021	Riverine nitrogen loading to the continental shelf sea is important for terrestrial-marine linkage and global nitrogen cycling and leads to serious marine environmental problems.	Nitrogen	9-17	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	51-54
34380095-1	2021	Riverine nitrogen loading to the continental shelf sea is important for terrestrial-marine linkage and global nitrogen cycling and leads to serious marine environmental problems.	Nitrogen	110-118	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	51-54
31586598-0	2020	A novel approach for production of an active N-terminally truncated Ulp1 (SUMO protease 1) catalytic domain from Escherichia coli inclusion bodies.	Nitrogen	45-46	SUMO protease ULP1	Saccharomyces cerevisiae S288C	68-72
34708977-2	2021	Inorganic nitrogen pollution in the coastal waters of Guangdong-Hong Kong-Macao Greater Bay Area(GBA) is a serious problem.	Nitrogen	10-18	glucosylceramidase beta	Homo sapiens	97-100
34708977-4	2021	Therefore, clarification of the scale, structure, and discharge pressure of nitrogen emissions from the land area of the GBA is needed to manage marine nitrogen pollution.	Nitrogen	76-84	glucosylceramidase beta	Homo sapiens	121-124
31586598-5	2020	In the current study, we demonstrate an alternative route for producing active Ulp1 catalytic domain from a His-tagged N-terminally truncated variant, residues 416-621, which is expressed in E. coli inclusion bodies and subsequently refolded.	Nitrogen	119-120	SUMO protease ULP1	Saccharomyces cerevisiae S288C	79-83
34708977-4	2021	Therefore, clarification of the scale, structure, and discharge pressure of nitrogen emissions from the land area of the GBA is needed to manage marine nitrogen pollution.	Nitrogen	152-160	glucosylceramidase beta	Homo sapiens	121-124
34708977-5	2021	Based on multi-source data, including land use, socio-economic statistics, and pollution source census information, the scale, source structure, and regional differences of total nitrogen discharge in GBA and surrounding cities were evaluated using administrative and watershed units.	Nitrogen	179-187	glucosylceramidase beta	Homo sapiens	201-204
31971671-0	2020	ZIF-8@ZIF-67-Derived Nitrogen-Doped Porous Carbon Confined CoP Polyhedron Targeting Superior Potassium-Ion Storage.	Nitrogen	21-29	caspase recruitment domain family member 16	Homo sapiens	59-62
34708977-7	2021	(2)The regional differences of total nitrogen emissions are obvious, and the total emissions from GBA(231400 t) are significantly higher than those from neighboring cities(101100 t).	Nitrogen	37-45	glucosylceramidase beta	Homo sapiens	98-101
34696588-6	2021	It is found that the process of transimination involving serine and PLP at the active site of the SHMT enzyme takes place through different elementary steps such as the formation of the first geminal diamine intermediate (GDI1), transfer of a proton from the substrate serine to the phenolic oxygen of PLP, followed by another proton transfer from PLP to the amine nitrogen of lysine with the formation of the second geminal diamine intermediate (GDI2), and finally, detachment of the active site lysine residue from PLP to produce the external aldimine.	Nitrogen	365-373	serine hydroxymethyltransferase 1	Homo sapiens	98-102
31971671-4	2020	The synthesis of ZIF-8@ZIF-67 derived nitrogen-doped porous carbon confined CoP polyhedron architectures (NC@CoP/NC) to function as innovative KIB anode materials is reported.	Nitrogen	38-46	caspase recruitment domain family member 16	Homo sapiens	76-79
31639410-0	2020	Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.	Nitrogen	0-8	fos-like antigen 1	Mus musculus	39-44
31639410-0	2020	Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.	Nitrogen	0-8	FBJ osteosarcoma oncogene	Mus musculus	73-78
34726276-2	2022	OTC plays a crucial role in the breakdown and removal of nitrogen in the body.	Nitrogen	57-65	ornithine transcarbamylase	Homo sapiens	0-3
31639410-3	2020	In nitrogen-mustard-exposed mouse skin, we found p-ERK activation increased Fra-1 and FosB.	Nitrogen	3-11	fos-like antigen 1	Mus musculus	76-81
31639410-5	2020	In nitrogen-mustard-exposed cultured immortalized human keratinocytes (HaCaT cells), Fra-1 in the nucleus functioned as an inhibitor of inflammatory cytokine interleukin (IL)-8.	Nitrogen	3-11	FOS like 1, AP-1 transcription factor subunit	Homo sapiens	85-90
31639410-8	2020	In conclusion, Fra-1 trapped in the cytoplasm after nitrogen mustard exposure might be a driving force for IL-8 over-expression in injured skin.	Nitrogen	52-60	fos-like antigen 1	Mus musculus	15-20
34438249-1	2021	Delta-5 desaturase (D5D) is a rate-limiting enzyme that introduces double-bonds to the delta-5 position of the n-3 and n-6 polyunsaturated fatty acid chain.	Nitrogen	111-112	fatty acid desaturase 1	Homo sapiens	0-18
34438249-1	2021	Delta-5 desaturase (D5D) is a rate-limiting enzyme that introduces double-bonds to the delta-5 position of the n-3 and n-6 polyunsaturated fatty acid chain.	Nitrogen	119-120	fatty acid desaturase 1	Homo sapiens	0-18
31654875-11	2020	New MARPOL regulations for passenger ships on the Baltic Sea require advanced treatment of pollutant nutrients, nitrogen and phosphorus, before sewage discharge in order to combat eutrophication of this sensitive area.	Nitrogen	112-120	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	57-60
31996710-6	2020	pH-dependent OGR1-mediated signalling led to a significant upregulation in the ER stress markers, binding immunoglobulin protein (BiP) and phospho-inositol required 1alpha (IRE1alpha), which was reversed by a novel OGR1 inhibitor and a c-Jun N-terminal kinase (JNK) inhibitor.	Nitrogen	242-243	G protein-coupled receptor 68	Homo sapiens	13-17
34822668-6	2021	In this study, the production of proinflammatory mediators, such as nitrogen oxide and prostaglandin E2, was induced by 1-NP in a concentration-dependent manner through the expression of iNOS and COX2.	Nitrogen	68-76	inositol-3-phosphate synthase 1	Homo sapiens	187-191
34643859-12	2022	Furthermore, TRIM3 overexpression significantly eased the LPS-induced damage on AKI rat model and decreased the serum creatinine and urea nitrogen levels in rat kidney tissues.	Nitrogen	138-146	tripartite motif-containing 3	Rattus norvegicus	13-18
34363947-4	2021	Cytokine (a mixture of IL-1beta, TNF-alpha, and IFN-gamma) treated AQP8 KD cells exhibited pronounced sensitivity to reactive oxygen and nitrogen species (ROS and RNS), resulting in a significant loss of beta-cell viability due to enhanced toxicity of the increased concentrations of H2O2 and hydroxyl radicals ( OH) in mitochondria of AQP8 KD cells.	Nitrogen	137-145	interferon gamma	Rattus norvegicus	48-57
34477187-1	2021	Guanosine deaminase (GSDA) in plants specifically deaminates (de)guanosine to produce xanthosine with high specificity, which is further converted to xanthine, a key intermediate in purine metabolism and nitrogen recycling.	Nitrogen	204-212	Cytidine/deoxycytidylate deaminase family protein	Arabidopsis thaliana	0-19
31996710-6	2020	pH-dependent OGR1-mediated signalling led to a significant upregulation in the ER stress markers, binding immunoglobulin protein (BiP) and phospho-inositol required 1alpha (IRE1alpha), which was reversed by a novel OGR1 inhibitor and a c-Jun N-terminal kinase (JNK) inhibitor.	Nitrogen	242-243	G protein-coupled receptor 68	Homo sapiens	215-219
34575794-5	2021	However, the gene expression of FRE1 and CTR1 was downregulated by nitrogen starvation.	Nitrogen	67-75	high-affinity Cu transporter CTR1	Saccharomyces cerevisiae S288C	41-45
34575794-6	2021	The protein level of Ctr1 was also decreased by nitrogen starvation, and addition of copper to the nitrogen starvation medium partially restored iron uptake activity.	Nitrogen	48-56	high-affinity Cu transporter CTR1	Saccharomyces cerevisiae S288C	21-25
31932450-6	2020	The superfusion of CeA slices with nociceptin/orphanin FQ peptide (N/OFQ; 500 nM), an endogenous opioid-like peptide, normalized GABA transmission in HA rats.	Nitrogen	67-68	prepronociceptin	Rattus norvegicus	35-45
34575794-6	2021	The protein level of Ctr1 was also decreased by nitrogen starvation, and addition of copper to the nitrogen starvation medium partially restored iron uptake activity.	Nitrogen	99-107	high-affinity Cu transporter CTR1	Saccharomyces cerevisiae S288C	21-25
31932450-6	2020	The superfusion of CeA slices with nociceptin/orphanin FQ peptide (N/OFQ; 500 nM), an endogenous opioid-like peptide, normalized GABA transmission in HA rats.	Nitrogen	67-68	prepronociceptin	Rattus norvegicus	46-57
31937660-5	2020	Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin retention.	Nitrogen	80-81	CCCTC-binding factor like	Homo sapiens	18-23
34567092-5	2021	The presence in the patient"s serum of the pathognomonic N-linked mannose-deprived tetrasaccharide marker for ALG1-CDG (Neu5Acalpha2,6Galbeta1,4-GlcNAcbeta1,4GlcNAc) further supported this diagnosis.	Nitrogen	57-58	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	110-114
31592648-6	2020	Our system is applicable to high-throughput ligand screening, and we discovered a new small molecule candidate that binds to the N-terminal ATP binding domain of Hsp90.	Nitrogen	129-130	heat shock protein 90 alpha family class A member 1	Homo sapiens	162-167
34404041-13	2021	We illustrate the identification of unresponsive subspaces and ranked responsive directions for gas sensor arrays based on Co-MOF-74 and HKUST-1 aimed at quantitative sensing of CH4/N2/CO2/C2H6mixtures relevant to natural gas sensing.	Nitrogen	182-184	gastrin	Homo sapiens	96-99
34404041-13	2021	We illustrate the identification of unresponsive subspaces and ranked responsive directions for gas sensor arrays based on Co-MOF-74 and HKUST-1 aimed at quantitative sensing of CH4/N2/CO2/C2H6mixtures relevant to natural gas sensing.	Nitrogen	182-184	gastrin	Homo sapiens	222-225
34502494-0	2021	Impact of Reactive Oxygen and Nitrogen Species Produced by Plasma on Mdm2-p53 Complex.	Nitrogen	30-38	transformed mouse 3T3 cell double minute 2	Mus musculus	69-73
34502494-0	2021	Impact of Reactive Oxygen and Nitrogen Species Produced by Plasma on Mdm2-p53 Complex.	Nitrogen	30-38	transformation related protein 53, pseudogene	Mus musculus	74-77
34351818-3	2021	OBJECTIVES: We investigated the accuracy of oxygen and carbon dioxide gas sensor measurements used for the indirect calculation of nitrogen concentration in a commercial multiple-breath washout device (Exhalyzer D, Eco Medics AG, Duernten, Switzerland) and its impact on functional residual capacity and lung clearance index.	Nitrogen	131-139	gastrin	Homo sapiens	70-73
34380307-5	2021	In contrast, the Si-N bond of the analogous vinylidene (R2(Me2N)Si-(R)Si (NHC)Ge:) (obtained by nucleophilic substitution of Cl by NMe2) does not oxidatively add to Ni(0), and a hydridosilagermene-eta2-nickel complex is obtained instead.	Nitrogen	20-21	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	131-135
34489886-1	2021	The ability of marine diazotrophs to fix dinitrogen gas (N2) is one of the most influential yet enigmatic processes in the ocean.	Nitrogen	57-59	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	52-55
34380733-6	2021	Mechanistically, we find that CWH43 deletion leads to decreased N-glycosylation of L1CAM, decreased association of L1CAM with cell membrane lipid microdomains, increased L1CAM cleavage by plasmin, and increased shedding of cleaved L1CAM in the cerebrospinal fluid.	Nitrogen	64-65	cell wall biogenesis 43 C-terminal homolog	Homo sapiens	30-35
34338500-3	2021	Herein, we report a fluorine-enriched nitrogen-doped hollow carbon spheres decorated carbon fibers (FNCS@CF) skeleton which effectively integrates the uniformly distributed lithophilic sites and mechanically robust LiF-enriched SEI, thus endowing the composite Li metal anode with durable and dendrite-free features.	Nitrogen	38-46	LIF interleukin 6 family cytokine	Homo sapiens	215-218
34288694-0	2021	N2 Gas Adsorption Sites of Single-Walled Carbon Nanotube Bundles: Identifying Interstitial Channels at Very Low Relative Pressure.	Nitrogen	0-2	gastrin	Homo sapiens	3-6
34402939-2	2021	In this study, a comparative metabolomics strategy revealed the metabolic regulatory mechanism of MYP overproduction, comparing ammonium chloride with peptone as nitrogen sources.	Nitrogen	162-170	nucleolar protein 3	Homo sapiens	98-101
34182225-17	2021	Particularly, a surplus of nitrogen supply via the aminogenic diet affected metabolic responses and stimulated insulin and glucagon secretion.	Nitrogen	27-35	insulin	Bos taurus	111-118
34110134-3	2021	The mechanism of N-hydroxylation of ArNH2 by CYP1A2 is investigated by density functional theory (DFT) calculations.	Nitrogen	17-18	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	45-51
34094685-7	2021	In xenograft model, glycosylation deficiency of Siglec15 reduced tumor growth in C57BL/6 mice, but had no impact in nude mice, indicating the requirement of N-glycosylation for immunosuppressive function of Siglec15.	Nitrogen	157-158	sialic acid binding Ig-like lectin 15	Mus musculus	207-215
35180604-3	2022	Herein, site-specific N-glycoprofiling of two major glycoproteins - immunoglobulin G (IgG) and lactoferrin (Lf) from goat milk was performed through RP-UHPLC Q-Tof MS/MS approach.	Nitrogen	22-23	lactotransferrin	Bos taurus	95-106
35147211-6	2022	This work uses a one-dimensional biofilm model to study the influence of the affinity constant, the maximum growth rate and the growth yield on the heterotrophic formation of dinitrogen gas (N2 ) in a completely autotrophic Partial Nitritation Anammox (PN/A) system.	Nitrogen	175-185	gastrin	Homo sapiens	186-189
35147211-6	2022	This work uses a one-dimensional biofilm model to study the influence of the affinity constant, the maximum growth rate and the growth yield on the heterotrophic formation of dinitrogen gas (N2 ) in a completely autotrophic Partial Nitritation Anammox (PN/A) system.	Nitrogen	191-193	gastrin	Homo sapiens	186-189
35358383-5	2022	In contrast to all-carbon nanobelts, NB1 and NB2 contain multiple pyrrolic nitrogen donors that could serve as potential metal coordination sites.	Nitrogen	75-83	CD177 molecule	Homo sapiens	37-40
35605046-8	2022	Under normal demand on urea cycle function, OTC expression in hemizygous males, although reduced, is sufficient to meet the demand for waste nitrogen excretion.	Nitrogen	141-149	ornithine transcarbamylase	Homo sapiens	44-47
35525001-3	2022	The results revealed that the main N-containing gases produced during the combustion of SS and CS were NH3 generated from Amino-N at 200-400  C and HCN generated from heterocyclic nitrogen at 400-600  C, respectively.	Nitrogen	35-36	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	148-151
35525001-3	2022	The results revealed that the main N-containing gases produced during the combustion of SS and CS were NH3 generated from Amino-N at 200-400  C and HCN generated from heterocyclic nitrogen at 400-600  C, respectively.	Nitrogen	180-188	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	148-151
35546738-2	2022	Peroxiredoxin V (PRDX5) scavenges ROS and reactive nitrogen species and is known to regulate several physiological and pathological reactions.	Nitrogen	51-59	peroxiredoxin 5	Homo sapiens	0-15
35546738-2	2022	Peroxiredoxin V (PRDX5) scavenges ROS and reactive nitrogen species and is known to regulate several physiological and pathological reactions.	Nitrogen	51-59	peroxiredoxin 5	Homo sapiens	17-22
35442033-5	2022	Complex 3 is the most reactive N atom transfer reagent among isolated nitrido complexes; it reacts with PPh3 and styrene with second-order rate constants of 2.12 x 105 and 1.95 x 10-2 M-1 s-1, respectively, which are >107 faster than that of 2.	Nitrogen	31-32	protein phosphatase 4 catalytic subunit	Homo sapiens	104-108
35085618-0	2022	MgO-loaded nitrogen and phosphorus self-doped biochar: High-efficient adsorption of aquatic Cu2+, Cd2+, and Pb2+ and its remediation efficiency on heavy metal contaminated soil.	Nitrogen	11-19	CD2 molecule	Homo sapiens	98-101
35566244-5	2022	The data obtained from the EDX analysis of the novel cross-linked copolymers confirmed the functionalization with aminobenzoic groups through the presence and content of nitrogen, as follows: PAB1: N% = 0.47; PAB2: N% = 0.85; and PAB3: N% = 1.30.	Nitrogen	170-178	poly(A) binding protein nuclear 1	Homo sapiens	209-213
35385269-7	2022	The high gas response was attributed to the catalytic effect promoted by the uniformly distributed Co-exsolved nanoparticles and the formation of p-n junctions on the sensing surface during reduction.	Nitrogen	148-149	gastrin	Homo sapiens	9-12
35621746-11	2022	Some putative N-glycosylated sites were found in GpSUC1a but none in BmSUC1, while there was more methylation in BmSUC1 than in GpSUC1a, indicating that such PTMs were supporting the differential beta-FFases activities in these two mulberry feeding caterpillars.	Nitrogen	14-15	beta-fructofuranosidase	Bombyx mori	113-119
34282273-12	2021	Additionally, the mutation of CD44 with six N-glycosylation sites showed less sensibility to NEU4 on cell migration compared with wild-type CD44.	Nitrogen	44-45	sialidase 4	Mus musculus	93-97
34075526-1	2021	NTPDase5 is a nucleotidase of the endoplasmic reticulum that plays an important role in proteostasis as a regulator of protein N-glycosylation.	Nitrogen	127-128	ectonucleoside triphosphate diphosphohydrolase 5 (inactive)	Homo sapiens	0-8
34462883-2	2022	Previous studies from our group and others indicated that Cav-1 could mediate N-glycosylation, alpha2,6-sialylation, and fucosylation in mouse hepatocarcinoma cells in vitro.	Nitrogen	78-79	caveolin 1, caveolae protein	Mus musculus	58-63
34417891-12	2021	In conclusion, milk yield, milk fat, protein, and lactose yields increased; however, decreased MNE indicates relatively greater N losses as observed by increased N excretion rate when CP level increased from 9.26 to 11.4% in the diet of lactating buffaloes.	Nitrogen	128-129	ceruloplasmin	Homo sapiens	184-186
34417891-12	2021	In conclusion, milk yield, milk fat, protein, and lactose yields increased; however, decreased MNE indicates relatively greater N losses as observed by increased N excretion rate when CP level increased from 9.26 to 11.4% in the diet of lactating buffaloes.	Nitrogen	162-163	ceruloplasmin	Homo sapiens	184-186
34106509-1	2021	MCO 3 (M=Zn, Cd, Hg) engages in a spodium bond with nitrogen-containing bases (HCN, NHCH 2 , NH 3 ) and a pnicogen bond with FH 2 Z (Z=P, As, Sb).	Nitrogen	52-60	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	79-82
34489931-12	2021	FHR1 and FHR5 binding was primarily mediated by N-sulfation while FH binding depended on N-, 2-O- and 6-O-sulfation.	Nitrogen	48-49	complement factor H related 1	Homo sapiens	0-4
34323905-6	2021	From eta1-O, subsequent N-O bond dissociation to liberate N2, producing (CoO(H2O)n)+, is straightforward via a mechanism that is commonplace for typical metal-catalyzed N2O decompositions.	Nitrogen	58-60	secreted phosphoprotein 1	Homo sapiens	5-9
34089282-5	2021	Here, we demonstrate a strategy for boosting the selectivity of BD by suppressing dehydroisomerization, an inevitable step in the conventional n -BDH process which largely reduces the selectivity of BD.	Nitrogen	143-144	3-hydroxybutyrate dehydrogenase 1	Homo sapiens	146-149
34341353-7	2021	Notably, N-induced lung injury and cytokine production are blocked by MCC950 (a specific inhibitor of NLRP3) and Ac-YVAD-cmk (an inhibitor of caspase-1).	Nitrogen	9-10	NLR family, pyrin domain containing 3	Mus musculus	102-107
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	22-23	hypothetical protein	Arabidopsis thaliana	151-171
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	22-23	hypothetical protein	Arabidopsis thaliana	173-175
34089296-9	2021	Therefore, we proposed that the ESCRT-III machinery mediates nitrogen starvation-induced macromitophagy by the interaction between Snf7 and Atg11 so that Snf7 is recruited to Atg32 marked MPs by the known Atg11-Atg32 interaction to seal them.	Nitrogen	61-69	mitophagy protein ATG32	Saccharomyces cerevisiae S288C	175-180
35387450-3	2022	Iron catalysts are utilized to accelerate the reaction, but high temperatures and pressures of atmospheric nitrogen gas (N2) and hydrogen gas (H2) are required.	Nitrogen	107-115	gastrin	Homo sapiens	116-119
35387450-3	2022	Iron catalysts are utilized to accelerate the reaction, but high temperatures and pressures of atmospheric nitrogen gas (N2) and hydrogen gas (H2) are required.	Nitrogen	121-123	gastrin	Homo sapiens	116-119
31964861-4	2020	De novo chromatin access, stable binding, and redistribution of partner TFs both require PU.1"s N-terminal acidic activation domain and its ability to recruit SWI/SNF remodeling complexes, suggesting that the latter may collect and distribute co-associated TFs in conjunction with the non-classical pioneer TF PU.1.	Nitrogen	96-97	Spi-1 proto-oncogene	Homo sapiens	89-93
35408715-1	2022	Herein, the adsorption characteristics of graphene substrates modified through a combined single manganese atom with a vacancy or four nitrogen to CH2O, H2S and HCN, are thoroughly investigated via the density functional theory (DFT) method.	Nitrogen	135-143	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	161-164
35219151-6	2022	Thus, we next modified the PAS scaffold to reduce NAT-1 catalyzed inactivation by introduction of groups to sterically block N-acetylation and fluorination of the aryl ring of PAS to attenuate N-acetylation by electronically deactivating the para-amino group.	Nitrogen	193-194	N-acetyl transferase 1	Mus musculus	50-55
35121374-7	2022	Inhibition of miR-448 reduced serum IgG and anti-dsDNA IgG contents, 24 h urine protein and blood urea nitrogen (BUN) levels, increased complement C3 concentration, and ameliorated splenomegaly and lymphadenectasis in MRL/lpr mice.	Nitrogen	103-111	microRNA 448	Mus musculus	14-21
35091499-0	2022	CAR T-cell Efficacy in Solid Tumors Is Affected by N-glycosylation.	Nitrogen	51-52	CXADR pseudogene 1	Homo sapiens	0-3
34497692-11	2021	Nevertheless, the mean percentage of Neu N-positive cells was significantly higher in differentiated cells with embryoid bodies" source, especially in the presence of SHH than other groups (P <= 0.05).	Nitrogen	41-42	sonic hedgehog signaling molecule	Homo sapiens	167-170
34212653-6	2021	The NBN area exhibited the best water quality, with COD and total nitrogen concentration values of 6.9 mg L-1 and 1.82 mg L-1, respectively.	Nitrogen	66-74	nibrin	Homo sapiens	4-7
34212669-3	2021	The results of reaction thermodynamics showed that the nitrogen removal performance of the granules acclimated to low temperature (GL) was significantly higher than that of those cultivated at medium-high temperature (GH) under the low temperature (10-20C), and the apparent activation energy (Ea) of total inorganic nitrogen removal for the former was decreased by 28.4%.	Nitrogen	55-63	gamma-glutamyl hydrolase	Homo sapiens	218-220
34212669-3	2021	The results of reaction thermodynamics showed that the nitrogen removal performance of the granules acclimated to low temperature (GL) was significantly higher than that of those cultivated at medium-high temperature (GH) under the low temperature (10-20C), and the apparent activation energy (Ea) of total inorganic nitrogen removal for the former was decreased by 28.4%.	Nitrogen	317-325	gamma-glutamyl hydrolase	Homo sapiens	218-220
34356323-2	2021	Reactive oxygen and nitrogen species (ROS and RNS) are byproducts of cellular metabolism that exert signaling functions in several cellular processes, including lipolysis and lipogenesis.	Nitrogen	20-28	FAM20C golgi associated secretory pathway kinase	Homo sapiens	46-49
35180452-4	2022	METHODS: Three experiments simulating different RMR and RER by controlled pure gas (N2 and CO2) infusions were conducted on 5 non-consecutive days.	Nitrogen	84-86	IK cytokine	Homo sapiens	56-59
34111921-2	2021	With Sc(OTf)3 as Lewis acid catalyst, the N-H functionalization of carbazoles takes place through a highly selective nitrogen-initiated nucleophilic ring opening reaction.	Nitrogen	117-125	POU class 5 homeobox 1	Homo sapiens	5-13
31931858-10	2020	N-Shh stimulation of cells significantly increased reporter activity in NSCLC cell lines, while Gli-i treatment of transfected cells showed less relative reporter activity.	Nitrogen	0-1	sonic hedgehog signaling molecule	Homo sapiens	2-5
34124911-10	2021	Because XBP1-HBP controls N-glycosylation of the extracellular matrix (ECM) in EMT, this novel IKKbeta-XBP1-HBP pathway may contain therapeutic targets whose inhibition could prevent ECM remodeling in lung fibrosis or other airway remodeling diseases.	Nitrogen	26-27	X-box binding protein 1	Homo sapiens	8-12
35268729-1	2022	We used a grand canonical Monte Carlo simulation to study the influence of impurities including water vapor, SO2, and O2 in the flue gas on the adsorption of CO2/N2 mixture in carbon nanotubes (CNTs) and carboxyl doped CNT arrays.	Nitrogen	162-164	gastrin	Homo sapiens	133-136
31931858-11	2020	When subjected to both Gli-i and N-Shh treatment, NSCLC cell lines continued to demonstrate decreased Gli transcriptional activity.	Nitrogen	33-34	sonic hedgehog signaling molecule	Homo sapiens	35-38
35268729-9	2022	In addition, it was found that (7, 7) CNT always maintained the best CO2/N2 adsorption and separation performance in the presence of impurity gas, for both the cases of single CNT and CNT array.	Nitrogen	73-75	gastrin	Homo sapiens	142-145
34089346-0	2021	ARL15 modulates magnesium homeostasis through N-glycosylation of CNNMs.	Nitrogen	46-47	ADP ribosylation factor like GTPase 15	Homo sapiens	0-5
31931858-14	2020	Cells stimulated by N-Shh demonstrated greater mobility.	Nitrogen	20-21	sonic hedgehog signaling molecule	Homo sapiens	22-25
34089346-6	2021	Most importantly, we found that ARL15 is required for forming complex N-glycosylation of CNNMs.	Nitrogen	70-71	ADP ribosylation factor like GTPase 15	Homo sapiens	32-37
34089346-7	2021	Overexpression of ARL15 promotes complex N-glycosylation of CNNM3.	Nitrogen	41-42	ADP ribosylation factor like GTPase 15	Homo sapiens	18-23
31921408-6	2020	The newly identified proteolysis pathway, which employs the proteases Wss1 and SprT-like domain at the N-terminus (SPRTN), can directly hydrolyze the proteins in DPCs, thus offering a new venue for DPC repair in cells.	Nitrogen	103-104	SprT-like N-terminal domain	Homo sapiens	115-120
34089346-7	2021	Overexpression of ARL15 promotes complex N-glycosylation of CNNM3.	Nitrogen	41-42	cyclin and CBS domain divalent metal cation transport mediator 3	Homo sapiens	60-65
34089346-9	2021	Altogether, our results establish ARL15 as a novel negative regulator of Mg2+ transport by promoting the complex N-glycosylation of CNNMs.	Nitrogen	113-114	ADP ribosylation factor like GTPase 15	Homo sapiens	34-39
35129991-6	2022	Inspired by the visualization of the 3D pore structure, we proposed a graphene/silica/nitrogen model to evaluate the role of graphene in heat conduction: it can not only reduce effective gas collision (impede heat transport) but also enhance the gas-solid coupling effect.	Nitrogen	86-94	gastrin	Homo sapiens	187-190
35129991-6	2022	Inspired by the visualization of the 3D pore structure, we proposed a graphene/silica/nitrogen model to evaluate the role of graphene in heat conduction: it can not only reduce effective gas collision (impede heat transport) but also enhance the gas-solid coupling effect.	Nitrogen	86-94	gastrin	Homo sapiens	246-249
31901900-3	2020	Using biochemical assays, computer-aided docking/molecular dynamics simulations, and fluorescence microscopy, we found that RSV can operate as a direct inhibitor of glyco-PD-L1-processing enzymes (alpha-glucosidase/alpha-mannosidase) that modulate N-linked glycan decoration of PD-L1, thereby promoting the endoplasmic reticulum retention of a mannose-rich, abnormally glycosylated form of PD-L1.	Nitrogen	248-249	sucrase-isomaltase	Homo sapiens	197-214
35425543-13	2022	The LOI of PIF/MWCNTS increased with increasing MWCNT due to the nitrogen heterocyclic interaction between the PIF and MWCNTS.	Nitrogen	65-73	PIF1 5'-to-3' DNA helicase	Homo sapiens	11-14
35425543-13	2022	The LOI of PIF/MWCNTS increased with increasing MWCNT due to the nitrogen heterocyclic interaction between the PIF and MWCNTS.	Nitrogen	65-73	PIF1 5'-to-3' DNA helicase	Homo sapiens	111-114
34281194-4	2021	Both reactive oxygen and nitrogen species are in excess in CS-A cells and when the mitochondrial translocation of DRP1 is inhibited a reduction of these species is observed together with a recovery of mitochondrial integrity and a significant decrease of apoptosis.	Nitrogen	25-33	dynamin 1 like	Homo sapiens	114-118
31727855-4	2020	Structural analysis revealed that TTC5 binds near the ribosome exit tunnel and engages the N terminus of nascent tubulins.	Nitrogen	91-92	tetratricopeptide repeat domain 5	Homo sapiens	34-38
34209036-1	2021	Recently, membrane contactors have gained more popularity in the field of CO2 removal; however, achieving high purity and competitive recovery for poor soluble gas (H2, N2, or CH4) remains elusive.	Nitrogen	169-171	gastrin	Homo sapiens	160-163
34169548-0	2022	Root Angle in Maize Influences Nitrogen Capture and is regulated by CBL-interacting serine/threonine-protein kinase 15 (ZmCIPK15).	Nitrogen	31-39	CBL-interacting serine/threonine-protein kinase 15	Zea mays	68-118
34220544-5	2021	Nitrogen fractionation increased in the HP fed fish under SS, indicating enhanced dietary protein oxidation.	Nitrogen	0-8	haptoglobin-like	Sparus aurata	40-42
35198253-8	2022	MAGT1 also acts as an accessory protein for STT3B, as catalytic subunits of the oligosaccharyltransferase protein complex, which carries out glycan chain transfer to proteins in the endoplasmic reticulum during N-glycosylation.	Nitrogen	211-212	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	44-49
35141461-6	2022	We further identify other candidate ATX1 targets owing to reduced growth of atx1 mutant lines on guanine as a sole nitrogen source, which we attribute to loss of function of UOX1, encoding a urate oxidase, a cupro-enzyme involved in guanine assimilation.	Nitrogen	115-123	copper metallochaperone ATX1	Saccharomyces cerevisiae S288C	36-40
35141461-6	2022	We further identify other candidate ATX1 targets owing to reduced growth of atx1 mutant lines on guanine as a sole nitrogen source, which we attribute to loss of function of UOX1, encoding a urate oxidase, a cupro-enzyme involved in guanine assimilation.	Nitrogen	115-123	copper metallochaperone ATX1	Saccharomyces cerevisiae S288C	76-80
31678146-7	2020	Presence of N-glycan(s) reduces affinity of cell binding and growth regulation by Gal-1.	Nitrogen	12-13	galectin 1	Homo sapiens	82-87
34981577-4	2022	In this study, via examination by lectin blotting, HPLC, and mass spectrometry analysis, however, we found that the amounts of GlcNAc-branched tri-antennary N-glycans catalyzed by N-acetylglucosaminyltransferase IV (GnT-IV) and tetra-antennary N-glycans were significantly decreased in O-GlcNAc transferase knockdown cells (OGT-KD) compared with those in wild type cells.	Nitrogen	180-182	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	324-327
34189500-6	2021	Weanling pigs fed with E. coli challenge with lysozyme and PC treatments had significantly enhanced nutrient retentions of dry matter and energy (p < 0.05); however, there was a tendency to increase nitrogen digestibility.	Nitrogen	199-207	lysozyme C-3	Sus scrofa	46-54
31707356-5	2020	In the NanoBRET-based binding assay, SMO is N-terminally tagged with nanoluciferase (Nluc) and binding of BODIPY-cyclopamine is assessed by quantifying resonance energy transfer between receptor and ligand.	Nitrogen	7-8	smoothened, frizzled class receptor	Homo sapiens	37-40
34390632-1	2021	Sudden decompression can result in bubble formation as the result of nitrogen gas (N2) dissolved in tissue during disabled submarine escape (DISSUB).	Nitrogen	69-77	gastrin	Homo sapiens	78-81
34390632-1	2021	Sudden decompression can result in bubble formation as the result of nitrogen gas (N2) dissolved in tissue during disabled submarine escape (DISSUB).	Nitrogen	83-85	gastrin	Homo sapiens	78-81
35062878-4	2022	UGT2B10 is a phase II drug metabolizing enzyme involved in the N-glucuronidation of tertiary amine containing drugs.	Nitrogen	63-64	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	0-7
34974624-2	2022	Uncoupling protein (UCP) and alternative oxidase (AOX) exhibit a strong correlation with N and C metabolism.	Nitrogen	89-90	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	20-23
34974624-4	2022	Low N markedly increased AOX1a and UCP1 expression, alternative pathway capacity and UCP activity.	Nitrogen	4-5	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	35-39
34974624-4	2022	Low N markedly increased AOX1a and UCP1 expression, alternative pathway capacity and UCP activity.	Nitrogen	4-5	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	85-88
32153322-8	2020	The most differentially expressed genes were observed in carbohydrate metabolic process, lipid metabolic process, cellulose synthase activity, membrane transports, nitrogen compound metabolic process and chitinase activity related genes.	Nitrogen	164-172	basic endochitinase A	Triticum aestivum	204-213
34974624-5	2022	Eight-day-old aox1a/ucp1 seedlings were more sensitive to low N than Col-0 and single mutants, exhibiting lower primary root length and higher anthocyanin accumulation.	Nitrogen	62-63	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	20-24
34974624-6	2022	The net photosynthetic rate, electron transport rate, PSII actual photochemical efficiency, stomatal conductance and carboxylation efficiency were markedly decreased in ucp1 and aox1a/ucp1 compared to those in Col-0 and aox1a under low N stress; comparatively, chlorophyll content and non-photochemical quenching coefficient were the lowest and highest in aox1a/ucp1, respectively.	Nitrogen	236-237	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	169-173
34974624-6	2022	The net photosynthetic rate, electron transport rate, PSII actual photochemical efficiency, stomatal conductance and carboxylation efficiency were markedly decreased in ucp1 and aox1a/ucp1 compared to those in Col-0 and aox1a under low N stress; comparatively, chlorophyll content and non-photochemical quenching coefficient were the lowest and highest in aox1a/ucp1, respectively.	Nitrogen	236-237	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	184-188
34974624-8	2022	The C/N ratio in seeds, but not in leaves, is higher in aox1a/ucp1 than that in Col-0, aox1a and ucp1 under low N condition.	Nitrogen	6-7	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	62-66
34974624-9	2022	RNA-seq analysis revealed that many genes involved in photosynthesis and C/N metabolism were markedly down-regulated in aox1a/ucp1 under low N stress.	Nitrogen	75-76	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	126-130
34974624-9	2022	RNA-seq analysis revealed that many genes involved in photosynthesis and C/N metabolism were markedly down-regulated in aox1a/ucp1 under low N stress.	Nitrogen	141-142	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	126-130
34974624-10	2022	These results highlight the key roles of UCP1 and AOX1a in modulating photosynthetic capacity, C/N assimilation and distribution under low N stress.	Nitrogen	97-98	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	41-45
35537261-1	2022	In this work we present a time-resolved FTIR spectroscopic study on kinetics of atomic and molecular species, specifically CO, CN radical, N2, HCN and CO2 generated in a glow discharge of formamide-nitrogen-water mixture in a helium buffer gas.	Nitrogen	198-206	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	143-146
35378472-6	2022	Based on the multiple functions of nitrogen-doped carbon fibers and CeO2, Li-S batteries with NCF@CeO2 interlayers exhibit superior electrochemical performances, including a high discharge specific capacity of 1072.9 mAh g-1 at 0.2 C and a low capacity decay rate of only 0.063% per cycle after 1000 cycles.	Nitrogen	35-43	neutrophil cytosolic factor 4	Homo sapiens	94-97
31641075-4	2020	To demonstrate that SDG8-mediated regulation of RNA isoform expression is functionally relevant, we examined a putative regulatory gene, CONSTANS, CO-like and TOC1 101 (CCT101), whose nitrogen-responsive isoform-specific RNA expression is mediated by SDG8.	Nitrogen	184-192	histone-lysine N-methyltransferase	Arabidopsis thaliana	20-24
35248639-2	2022	Based on the soil sampling and survey data set, this study established the path analysis model of SANs (soil available nutrients, including ammonium nitrogen (AN), available phosphorus (AP) and available potassium (AK)) with topography, climate and vegetation in order to explore how environmental factors interact to affect the content of SANs.	Nitrogen	149-157	USH1 protein network component sans	Homo sapiens	98-102
35325216-7	2022	Among the glutamine synthetase (GS) family genes, we found that BnaA2.Gln1;4, significantly responsive to low-nitrogen conditions, showed higher transcription abundance and GS activity in the leaf veins, flower sepals, root cortex and stele, silique petiole, and stem tissues.	Nitrogen	110-118	hypothetical protein	Arabidopsis thaliana	10-30
35325216-7	2022	Among the glutamine synthetase (GS) family genes, we found that BnaA2.Gln1;4, significantly responsive to low-nitrogen conditions, showed higher transcription abundance and GS activity in the leaf veins, flower sepals, root cortex and stele, silique petiole, and stem tissues.	Nitrogen	110-118	hypothetical protein	Arabidopsis thaliana	32-34
35620880-5	2022	The data analysis indicated that the Schiff base contains bidentate nitrogen sulfur (NS) domains and was coordinated to silicon (Si) and tin (Sn) moieties via the imine-N and thiolic-S atoms, resulting in penta- and hexa-coordinated complexes in 1 : 1 and 1 : 2 ratios, respectively.	Nitrogen	169-170	hexosaminidase subunit alpha	Homo sapiens	216-220
35219056-4	2022	The FTIR and chemical quantitative analysis showed that nitrogen-containing gaseous products predominately contained (CN)2, HCN and small amounts of NH3 and NOx.	Nitrogen	56-64	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	124-127
35465290-8	2022	In comparison with serum median OPN levels, serum OPN level was positively associated with KT duration (P = 0.048), serum blood urea nitrogen (BUN; P = 0.043), and serum creatinine levels (P = 0.045) but negatively associated with estimated glomerular filtration rate (eGFR; P = 0.049).	Nitrogen	133-141	secreted phosphoprotein 1	Homo sapiens	50-53
31641075-4	2020	To demonstrate that SDG8-mediated regulation of RNA isoform expression is functionally relevant, we examined a putative regulatory gene, CONSTANS, CO-like and TOC1 101 (CCT101), whose nitrogen-responsive isoform-specific RNA expression is mediated by SDG8.	Nitrogen	184-192	histone-lysine N-methyltransferase	Arabidopsis thaliana	251-255
31641075-6	2020	We conclude that SDG8 is involved in plant responses to environmental nitrogen supply, affecting multiple gene regulatory processes including genome-wide histone modification, transcriptional regulation, and RNA processing, and thereby mediating developmental and metabolic processes related to nitrogen use.	Nitrogen	70-78	histone-lysine N-methyltransferase	Arabidopsis thaliana	17-21
35595358-3	2022	In the present work, we report a facile strategy to obtain nitrogen and phosphorous co-doped glucose-derived carbon coated CoP nanowires (G-CoP/N,P-C NWs), in which nitrilotriacetic acid (NTA) was as the chelating reagent, glucose was as carbon source, and the precursors were subsequently experienced carbonization and phosphorization process.	Nitrogen	59-67	caspase recruitment domain family member 16	Homo sapiens	123-126
35595358-3	2022	In the present work, we report a facile strategy to obtain nitrogen and phosphorous co-doped glucose-derived carbon coated CoP nanowires (G-CoP/N,P-C NWs), in which nitrilotriacetic acid (NTA) was as the chelating reagent, glucose was as carbon source, and the precursors were subsequently experienced carbonization and phosphorization process.	Nitrogen	59-67	caspase recruitment domain family member 16	Homo sapiens	140-143
31641075-6	2020	We conclude that SDG8 is involved in plant responses to environmental nitrogen supply, affecting multiple gene regulatory processes including genome-wide histone modification, transcriptional regulation, and RNA processing, and thereby mediating developmental and metabolic processes related to nitrogen use.	Nitrogen	295-303	histone-lysine N-methyltransferase	Arabidopsis thaliana	17-21
35192852-4	2022	Based on the analysis of transcriptomics and nitrogen metabolites, this study showed that 400 mg L-1 GO exposure downregulated most of the genes encoding nitrogen-assimilating enzymes, including nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	154-162	glutamate dehydrogenase 1	Homo sapiens	278-301
32253875-7	2020	This mutation in the STT3B gene affects the catalytic subunit of the oligosaccharyltransferase and the recipient substrate properties, which in part have the same functions in N-glycosylation.	Nitrogen	176-177	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	21-26
35192852-4	2022	Based on the analysis of transcriptomics and nitrogen metabolites, this study showed that 400 mg L-1 GO exposure downregulated most of the genes encoding nitrogen-assimilating enzymes, including nitrate reductase (NR), glutamine synthetase (GS), glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	154-162	glutamate dehydrogenase 1	Homo sapiens	303-306
35596004-7	2022	Furthermore, when N-linked glycosylation and disulfide bond formation are blocked, the cleavage and fusogenic activity of syncytin-2 are inhibited.	Nitrogen	18-19	endogenous retrovirus group FRD member 1, envelope	Homo sapiens	122-132
35596011-3	2022	In this study, a single-atomic palladium-loaded nitrogen-doped porous carbon catalyst (SA-Pd/NPC) was prepared and used as a mimetic peroxidase to catalyze the substrates oxidation.	Nitrogen	48-56	NPC intracellular cholesterol transporter 1	Homo sapiens	87-96
31697501-2	2019	Correlating simulations with experimental data from SPR kinetics measurements and X-ray crystallography on two small molecule compound libraries bound to the N-terminal domain of the chaperone Hsp90, we show that the mean non-equilibrium work computed in an ensemble of trajectories of enforced ligand unbinding is a promising predictor for ligand unbinding rates.	Nitrogen	158-159	heat shock protein 90 alpha family class A member 1	Homo sapiens	193-198
35629564-4	2022	After process optimization, the gas transport properties through the membranes were determined on the basis of pure gas permeation including CH4, CO2, O2, and N2 for two specific applications: biogas sweetening (CH4/CO2) and oxygen-enriched air (O2/N2).	Nitrogen	159-161	gastrin	Homo sapiens	32-35
35629564-4	2022	After process optimization, the gas transport properties through the membranes were determined on the basis of pure gas permeation including CH4, CO2, O2, and N2 for two specific applications: biogas sweetening (CH4/CO2) and oxygen-enriched air (O2/N2).	Nitrogen	159-161	gastrin	Homo sapiens	116-119
31861875-11	2019	Our results demonstrate that Galectin-8 is a new binding partner for K-Ras4B and it interacts via the N-CRD with the farnesylated PBD of K-Ras, thereby modulating the K-Ras effector pathways as well as cell proliferation and migration.	Nitrogen	102-103	galectin 8	Homo sapiens	29-39
35552412-3	2022	We initially observed altered leaf to seed ratios, faster senescence progression, altered leaf nitrogen recovery after transient nitrogen removal and ultimately enhanced nitrogen remobilization from the leaves in two methylation mutants (ros1 and the triple dmr1/2 cmt3 knockout).	Nitrogen	170-178	homoserine kinase	Arabidopsis thaliana	258-264
31857626-4	2019	In an angiotensin II (Ang II)-induced renal injury mouse model, we found that blocking AT1R and AT2R effectively mitigates Ang II-induced increases in necroptotic tubular epithelial cell percentages, necroptosis-related RIP3 and MLKL protein expression, serum creatinine and blood urea nitrogen levels, and tubular damage scores.	Nitrogen	286-294	angiotensin II, type I receptor-associated protein	Mus musculus	87-91
35507918-0	2022	Recent Progress in Dinitrogen Activation by Gas-Phase Metal Species.	Nitrogen	19-29	gastrin	Homo sapiens	44-47
35507918-2	2022	Reactions of gas-phase species with N2 are being actively studied to understand the bond activation and formation processes at a strictly molecular level.	Nitrogen	36-38	gastrin	Homo sapiens	13-16
35507918-3	2022	This Perspective provides an overview of the recent progress in combined experimental and theoretical studies on the activation and functionalization of N2 by gas-phase metal species.	Nitrogen	153-155	gastrin	Homo sapiens	159-162
35507918-5	2022	Finally, the current challenges and outlooks of N2 activation in the gas phase are discussed as well.	Nitrogen	48-50	gastrin	Homo sapiens	69-72
35533206-10	2022	Furthermore, Pns11 potentially blocks autophagosome degradation by directly targeting and mediating the reduced expression of N-glycosylated Lamp1 on lysosomal membranes.	Nitrogen	126-127	hypothetical protein	Saccharomyces cerevisiae S288C	13-18
35150821-6	2022	The mitochondria-related gene ATP12, MRPL22, MRP1 and NAM9 significantly increased the utilization of multiple non-preferred amino acids and reduced accumulation of the urea by coordinately regulating nitrogen catabolism repression, Ssy1p-Ptr3p-Ssy5p signaling sensor system, amino acid transporters, TOR pathway and urea metabolism-related pathways.	Nitrogen	201-209	mitochondrial 37S ribosomal protein MRP1	Saccharomyces cerevisiae S288C	45-49
31792183-9	2019	The homeodomain and N-terminal repression domain of Hhex were critical for inhibiting Foxp3 and other Treg signature genes.	Nitrogen	20-21	forkhead box P3	Mus musculus	86-91
31915448-6	2019	Siwu plus EPO treatment significantly increased the rat hemoglobin content (p &lt; 0.05) and reduced blood urea nitrogen (p &lt; 0.05) and serum creatinine (p &lt; 0.001).	Nitrogen	112-120	erythropoietin	Rattus norvegicus	10-13
35509259-5	2022	We could show that PGM1 is phosphorylated at a residue in the regulatory latch domain (Ser 47) during nitrogen starvation, which inhibits its activity.	Nitrogen	102-110	phosphoglucomutase 1	Homo sapiens	19-23
31822758-5	2019	We estimate that including nitrogen-fixing trees in Neotropical reforestation projects could safeguard the sequestration of 6.7 Gt CO2 over the next 20 years.	Nitrogen	27-35	complement C2	Homo sapiens	131-134
35502904-6	2022	Further characterization revealed a dependency of LCMV entry on the cysteine-rich domain of CD164, including an N-linked glycosylation site at residue 104 in that region.	Nitrogen	112-113	CD164 molecule	Homo sapiens	92-97
31819032-5	2019	The N-terminal RING domain of MARCH5 was required for the interaction with HBx, and MARCH5H43W lacking E3 ligase activity failed to reduce HBx protein levels.	Nitrogen	4-5	membrane associated ring-CH-type finger 5	Homo sapiens	30-36
35499203-3	2022	Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs).	Nitrogen	263-271	suprabasin	Homo sapiens	187-191
35499203-3	2022	Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs).	Nitrogen	263-271	suprabasin	Homo sapiens	295-299
35458199-2	2022	After 2 months of a LPD-a reduction in blood urea nitrogen (52 +- 17 vs. 46 +- 15 mg/dL, p = 0.003), total cholesterol (185 +- 41 vs. 171 +- 34 mg/dL, p = 0.001), and triglycerides (194 +- 148 vs. 161 +- 70 mg/dL, p = 0.03) was observed; 57 subjects were then randomized to receive probiotics or a placebo for the subsequent 3 months.	Nitrogen	50-58	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	Homo sapiens	20-23
31604529-8	2019	Altogether, N-termini of GRK2 and GRK3 efficiently simulate RKIP effects on beta-AR signaling in HEK293 cells and in cardiomyocytes by their binding to beta2-AR and, thus, provide important insights for the development of new strategies to modulate beta2-AR signaling.	Nitrogen	12-13	G protein-coupled receptor kinase 3	Homo sapiens	34-38
35191568-1	2022	Computational investigations were carried out to probe the potential of several dicoordinate, singly base-stabilized borylenes of the form (L BR) (L = neutral Lewis base) in dinitrogen binding.	Nitrogen	174-184	chromosome 12 open reading frame 73	Homo sapiens	142-144
31796894-6	2021	We have previously shown that the phospholipid, phosphatidylinositol (4, 5)-bisphosphate (PIP2), directly interacts with the DAT N-terminus to support DA efflux in response to AMPH.	Nitrogen	129-130	Dopamine transporter	Drosophila melanogaster	125-128
35357176-3	2022	Using the anion-induced outer surface interaction of Q(n)s derived from (CdxCly)n- anions formed by Cd2+ cations in a HCl medium, four different TMeQ(6)-(CdxCly)n--based supramolecular frameworks are constructed.	Nitrogen	55-58	CD2 molecule	Homo sapiens	100-103
31796894-7	2021	In this study, we demonstrate that the interaction of PIP2 with the DAT N-terminus is critical for AMPH-induced DAT phosphorylation, a process required for DA efflux.	Nitrogen	72-73	Dopamine transporter	Drosophila melanogaster	68-71
35411601-10	2022	Tradeoffs in BMP selection related to nitrogen reduction outcome and cost are also demonstrated.	Nitrogen	38-46	bone morphogenetic protein 1	Homo sapiens	13-16
31796894-7	2021	In this study, we demonstrate that the interaction of PIP2 with the DAT N-terminus is critical for AMPH-induced DAT phosphorylation, a process required for DA efflux.	Nitrogen	72-73	Dopamine transporter	Drosophila melanogaster	112-115
31841203-13	2019	The levels of creatinine and blood urea nitrogen in LPS + CRNDE siRNA group were notably lower than those of the LPS group (p&lt;0.05).	Nitrogen	40-48	colorectal neoplasia differentially expressed (non-protein coding)	Mus musculus	58-63
35407971-6	2022	The capture of miR-21 increased linearly with the increase in amino nitrogen measured on surfaces.	Nitrogen	68-76	microRNA 21	Homo sapiens	15-21
31807193-5	2019	No prior association has been reported between adenomatosis polyposis coli 2 (APC2), homeobox A9, Wnt family member 7A (WNT7A) and N-Myc downstream-regulated gene 4 protein genes with PCa.	Nitrogen	0-1	Wnt family member 7A	Homo sapiens	98-101
31807193-5	2019	No prior association has been reported between adenomatosis polyposis coli 2 (APC2), homeobox A9, Wnt family member 7A (WNT7A) and N-Myc downstream-regulated gene 4 protein genes with PCa.	Nitrogen	0-1	Wnt family member 7A	Homo sapiens	120-125
31615848-4	2019	These isoforms appear to act redundantly, including the plant-specific, truncated ATG1t variant, and like other well-characterized atg mutants, homozygous atg1abct plants display early leaf senescence and hypersensitivity to nitrogen and fixed-carbon starvation.	Nitrogen	225-233	transmembrane protein G1P-related 1	Arabidopsis thaliana	155-159
31615848-5	2019	Although the ATG1 kinase is essential for up-regulating autophagy under nitrogen deprivation and short-term carbon starvation, it did not stimulate autophagy under prolonged carbon starvation.	Nitrogen	72-80	transmembrane protein G1P-related 1	Arabidopsis thaliana	13-17
31783892-2	2019	Reducing N-linked glycosylation of PD-1 may decrease PD-1 expression and relieve its inhibitory effects on CAR-T cells.	Nitrogen	9-10	CXADR Ig-like cell adhesion molecule	Sus scrofa	107-110
31784668-8	2019	Warming not only negatively affected expressions of these genes, but also secondary pathways of nitrogen (N) metabolism, including key enzymes of GST30, GST7, GST26, GST15, GLUL and glnA.	Nitrogen	96-104	glutathione transferase30	Zea mays	146-151
31784668-8	2019	Warming not only negatively affected expressions of these genes, but also secondary pathways of nitrogen (N) metabolism, including key enzymes of GST30, GST7, GST26, GST15, GLUL and glnA.	Nitrogen	96-104	glutathione transferase 7	Zea mays	153-157
31784668-8	2019	Warming not only negatively affected expressions of these genes, but also secondary pathways of nitrogen (N) metabolism, including key enzymes of GST30, GST7, GST26, GST15, GLUL and glnA.	Nitrogen	106-107	glutathione transferase30	Zea mays	146-151
31784668-8	2019	Warming not only negatively affected expressions of these genes, but also secondary pathways of nitrogen (N) metabolism, including key enzymes of GST30, GST7, GST26, GST15, GLUL and glnA.	Nitrogen	106-107	glutathione transferase 7	Zea mays	153-157
31670934-3	2019	Moreover, the local atomic configuration and bond distance studies show that trivalent Co3+ states are partially reduced through nitrogen radicals in the plasma to low-coordinated bivalent Co2+ states playing as the facile adsorption sites of oxygen-evolving intermediates due to the decreased activation barrier for water oxidation.	Nitrogen	129-137	complement C2	Homo sapiens	189-192
32025450-1	2019	Using CALIPSO-CloudSat-Clouds and the Earth"s Radiant Energy System-Moderate Resolution Imaging Spectrometer data set, this study documents the seasonal variation of sea ice, cloud, and atmospheric properties in the Arctic (70 N-82 N) for 2007-2010.	Nitrogen	227-228	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	144-147
35092134-4	2022	Inhibitors of N-glycosylation were found to suppress the processing and trafficking of endogenous MET in H1975 and EBC-1 lung cancer cells and exogenous MET in CHO-K1 cells.	Nitrogen	14-15	SAFB like transcription modulator	Homo sapiens	98-101
35092134-4	2022	Inhibitors of N-glycosylation were found to suppress the processing and trafficking of endogenous MET in H1975 and EBC-1 lung cancer cells and exogenous MET in CHO-K1 cells.	Nitrogen	14-15	SAFB like transcription modulator	Homo sapiens	153-156
35043510-3	2022	To identify the regulatory mechanisms of N assimilation, we performed a genetic screen using a Chlamydomonas reinhardtii strain whose motility depends upon the transcription of nitrate reductase-encoding NIT1, which is upregulated in response to N starvation.	Nitrogen	41-42	uncharacterized protein	Chlamydomonas reinhardtii	177-194
35043510-3	2022	To identify the regulatory mechanisms of N assimilation, we performed a genetic screen using a Chlamydomonas reinhardtii strain whose motility depends upon the transcription of nitrate reductase-encoding NIT1, which is upregulated in response to N starvation.	Nitrogen	41-42	uncharacterized protein	Chlamydomonas reinhardtii	204-208
35043510-3	2022	To identify the regulatory mechanisms of N assimilation, we performed a genetic screen using a Chlamydomonas reinhardtii strain whose motility depends upon the transcription of nitrate reductase-encoding NIT1, which is upregulated in response to N starvation.	Nitrogen	246-247	uncharacterized protein	Chlamydomonas reinhardtii	177-194
35043510-3	2022	To identify the regulatory mechanisms of N assimilation, we performed a genetic screen using a Chlamydomonas reinhardtii strain whose motility depends upon the transcription of nitrate reductase-encoding NIT1, which is upregulated in response to N starvation.	Nitrogen	246-247	uncharacterized protein	Chlamydomonas reinhardtii	204-208
35293203-4	2022	The reported synthetic strategy allows us to tailor the physicochemical features of the CTF materials, including the nitrogen content, the apparent specific surface area, and optoelectronic properties.	Nitrogen	117-125	establishment of sister chromatid cohesion N-acetyltransferase 1	Homo sapiens	88-91
35453350-5	2022	Carnosine (beta-alanyl-L-histidine, Car) protects cells from the damage due to the reactive species derived from oxygen (ROS), nitrogen (RNS) or carbonyl groups (RCS).	Nitrogen	127-135	CXADR pseudogene 1	Homo sapiens	36-39
35219151-6	2022	Thus, we next modified the PAS scaffold to reduce NAT-1 catalyzed inactivation by introduction of groups to sterically block N-acetylation and fluorination of the aryl ring of PAS to attenuate N-acetylation by electronically deactivating the para-amino group.	Nitrogen	125-126	N-acetyl transferase 1	Mus musculus	50-55
35290524-6	2022	Nitrogen fixation capacities of 55 isolates varied between 2.29 and 46.11 microg mL-1 according to micro-kjeldahl method.	Nitrogen	0-8	L1 cell adhesion molecule	Mus musculus	81-85
32025450-1	2019	Using CALIPSO-CloudSat-Clouds and the Earth"s Radiant Energy System-Moderate Resolution Imaging Spectrometer data set, this study documents the seasonal variation of sea ice, cloud, and atmospheric properties in the Arctic (70 N-82 N) for 2007-2010.	Nitrogen	232-233	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	144-147
31647659-0	2019	Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N-Methylation for PI3Kdelta Activity.	Nitrogen	112-113	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Homo sapiens	46-71
35267651-8	2022	Suppressed N-glycosylation by 2DG or metformin + 2DG also caused PD-L1 deglycosylation and reduced surface expression in MDA-MB-231 cells.	Nitrogen	11-12	CD274 molecule	Homo sapiens	65-70
31647659-0	2019	Free-Wilson Analysis of Comprehensive Data on Phosphoinositide-3-kinase (PI3K) Inhibitors Reveals Importance of N-Methylation for PI3Kdelta Activity.	Nitrogen	112-113	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Homo sapiens	130-139
35246892-1	2022	Glutamine synthetase (GS, EC 6.3.1.2) is an essential enzyme in plant metabolism, catalysing the assimilation of inorganic nitrogen into the amino acid glutamine.	Nitrogen	123-131	hypothetical protein	Arabidopsis thaliana	0-20
31776360-4	2019	The mechanism involves signaling by mitochondria-generated H2O2 (mH2O2) acting via the redox sensor, peroxiredoxin-1, a thiol peroxidase with high reactivity towards H2O2 that activates c-Jun N-terminal kinase-2alpha2 (JNK2alpha2).	Nitrogen	192-193	peroxiredoxin 1	Mus musculus	101-116
35246892-1	2022	Glutamine synthetase (GS, EC 6.3.1.2) is an essential enzyme in plant metabolism, catalysing the assimilation of inorganic nitrogen into the amino acid glutamine.	Nitrogen	123-131	hypothetical protein	Arabidopsis thaliana	22-24
35216160-1	2022	Cold physical plasma (CPP), a partially ionized gas that simultaneously generates reactive oxygen and nitrogen species, is suggested to provide advantages in regenerative medicine.	Nitrogen	102-110	gastrin	Homo sapiens	48-51
31772376-4	2019	Using solid-state NMR, we found that the overall structure of the core of alphaS fibrils when co-incubated with betaS is minimally perturbed, however, the dynamics of Lys and Thr residues, located primarily in the imperfect KTKEGV repeats of the alphaS N-terminus, are increased.	Nitrogen	18-19	synuclein alpha	Homo sapiens	74-80
35144246-4	2022	It is shown the MoSe2-based nanomaterials have excellent selectivity to Nitrogen dioxide (NO2) according to gas sensing properties measurement.	Nitrogen	72-80	gastrin	Homo sapiens	108-111
31751425-2	2019	The difference in the banding pattern in Phos-tag SDS-PAGE between the WT and G2A-mutant FMNL2 indicated the presence of N-myristoylation-dependent phosphorylation sites in FMNL2.	Nitrogen	91-92	formin like 2	Homo sapiens	173-178
35048936-0	2022	The controlled synthesis of nitrogen and iron co-doped Ni3S2@NiP2 heterostructures for the oxygen evolution reaction and urea oxidation reaction.	Nitrogen	28-36	BCL2 interacting protein 2	Homo sapiens	61-65
35048936-2	2022	Herein, nitrogen and iron co-doped Ni3S2 and NiP2 heterostructures with high efficiency oxygen evolution reaction (OER) and urea oxidation reaction (UOR) performances were firstly successfully prepared on nickel foam by hydrothermal and high-temperature calcination methods.	Nitrogen	8-16	BCL2 interacting protein 2	Homo sapiens	45-49
31751425-3	2019	Phos-tag SDS-PAGE of FMNL2 mutants in which the putative phosphorylation sites listed in PhosphoSitePlus (an online database of phosphorylation sites) were changed to Ala revealed that Ser-171 and Ser-1072 are N-myristoylation-dependent phosphorylation sites in FMNL2.	Nitrogen	23-24	formin like 2	Homo sapiens	262-267
35173763-1	2021	The N-reductive enzyme system (NRES), composed of MARC1, MARC2, CYB5, and CYB5R, is responsible for the reduction of N-oxygenated compounds and participates in several physiological processes.	Nitrogen	4-5	mitochondrial amidoxime reducing component 2	Homo sapiens	57-62
35173763-1	2021	The N-reductive enzyme system (NRES), composed of MARC1, MARC2, CYB5, and CYB5R, is responsible for the reduction of N-oxygenated compounds and participates in several physiological processes.	Nitrogen	4-5	cytochrome b5 type A	Homo sapiens	64-68
35173763-1	2021	The N-reductive enzyme system (NRES), composed of MARC1, MARC2, CYB5, and CYB5R, is responsible for the reduction of N-oxygenated compounds and participates in several physiological processes.	Nitrogen	117-118	mitochondrial amidoxime reducing component 2	Homo sapiens	57-62
35173763-1	2021	The N-reductive enzyme system (NRES), composed of MARC1, MARC2, CYB5, and CYB5R, is responsible for the reduction of N-oxygenated compounds and participates in several physiological processes.	Nitrogen	117-118	cytochrome b5 type A	Homo sapiens	64-68
31751425-4	2019	Similar experiments with FMNL3 demonstrated that N-myristoylation-dependent phosphorylation occurs at a single Ser residue at position 174, which is a Ser residue conserved between FMNL2 and FMNL3, corresponding to Ser-171 in FMNL2.	Nitrogen	27-28	formin like 2	Homo sapiens	181-186
31697492-6	2019	A similar affinity of 0.3 nM is determined for the tripeptide Met-Asp-Val(MDV) that mimics the N-terminus of alphaSyn, while the incorporation of a putative histidine side chain in the N-terminal complex facilitates the formation of a macrochelate with the histidine, which results in an increase in the affinity for Cu2+ to 0.03 nM at pH 7.4.	Nitrogen	95-96	synuclein alpha	Homo sapiens	109-117
35128270-7	2022	When the doping amount of BBPMS is 70-80%, the O2/N2 gas permeation separation of the BBPMS/EC/IL ternary composite membrane is close to the Robertson 2008 curve.	Nitrogen	50-52	gastrin	Homo sapiens	53-56
34981926-8	2022	rARP"s higher catalytic efficiency was also in agreement with the shorter binding distance of H/N-His56 in rARP/substrate in comparison to that of HRP/substrate, as illustrated by docking simulation.	Nitrogen	96-98	kidney androgen regulated protein	Rattus norvegicus	0-4
34981926-8	2022	rARP"s higher catalytic efficiency was also in agreement with the shorter binding distance of H/N-His56 in rARP/substrate in comparison to that of HRP/substrate, as illustrated by docking simulation.	Nitrogen	96-98	kidney androgen regulated protein	Rattus norvegicus	107-111
34974624-0	2022	UCP1 and AOX1a contribute to regulation of carbon and nitrogen metabolism and yield in Arabidopsis under low nitrogen stress.	Nitrogen	54-62	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	0-4
34974624-0	2022	UCP1 and AOX1a contribute to regulation of carbon and nitrogen metabolism and yield in Arabidopsis under low nitrogen stress.	Nitrogen	109-117	plant uncoupling mitochondrial protein 1	Arabidopsis thaliana	0-4
31697492-6	2019	A similar affinity of 0.3 nM is determined for the tripeptide Met-Asp-Val(MDV) that mimics the N-terminus of alphaSyn, while the incorporation of a putative histidine side chain in the N-terminal complex facilitates the formation of a macrochelate with the histidine, which results in an increase in the affinity for Cu2+ to 0.03 nM at pH 7.4.	Nitrogen	185-186	synuclein alpha	Homo sapiens	109-117
31728037-8	2019	By systematically mutagenizing the residues of the LAT1 cytosolic tails, we identified a group of three close lysines (K19, K25, K30) in the N-terminal tail that are important for PMA-induced ubiquitylation and downregulation.	Nitrogen	141-142	solute carrier family 7 member 5	Homo sapiens	51-55
31728037-9	2019	Our study thus unravels a mechanism of induced endocytosis of LAT1 elicited by Nedd4-2-mediated ubiquitylation of the transporter"s N-terminal tail.	Nitrogen	79-80	solute carrier family 7 member 5	Homo sapiens	62-66
31603662-2	2019	Here, by selecting appreciate precursors of dopamine and a Co-containing metal-organic framework of ZIF-67, we subtly couple their reaction processes to develop a facile approach for the synthesis of a hollow CoP nanostructure with N-doped carbon skeleton (H-CoP@NC).	Nitrogen	232-233	caspase recruitment domain family member 16	Homo sapiens	209-212
31603662-2	2019	Here, by selecting appreciate precursors of dopamine and a Co-containing metal-organic framework of ZIF-67, we subtly couple their reaction processes to develop a facile approach for the synthesis of a hollow CoP nanostructure with N-doped carbon skeleton (H-CoP@NC).	Nitrogen	232-233	caspase recruitment domain family member 16	Homo sapiens	259-262
31615765-8	2019	Biochemical analysis for various post-translational modifications demonstrated that secreted invadolysin is both N- and O-glycosylated, but not apparently GPI-linked.	Nitrogen	113-114	leishmanolysin like peptidase	Homo sapiens	93-104
31553068-2	2019	Autoproteolysis cleaves latrophilin-1 into two parts: the extracellular N-terminal fragment (NTF) and the heptahelical C-terminal fragment (CTF).	Nitrogen	72-73	adhesion G protein-coupled receptor L1	Homo sapiens	24-37
31545417-8	2019	IgE-ELISA and western blot analysis showed that all of the Der f-human UQCRB hybrid proteins generated, except for the one lacking 59 residues of the N-terminal region of Der f 24, were bound by allergic serum IgE.	Nitrogen	150-151	ubiquinol-cytochrome c reductase binding protein	Homo sapiens	71-76
31606241-8	2019	In the 40 patients included, high METTL3 expression was associated with high pathological stage (P = 0.02) and high N stage (P = 0.02).	Nitrogen	116-117	methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit	Homo sapiens	34-40
2489100-0	1989	Synthesis and conformational analysis of Aib-containing peptide modelling for N-glycosylation site in N-glycoprotein.	Nitrogen	78-79	ANIB1	Homo sapiens	41-44
2489100-1	1989	A tetrapetide containing an Aib residue, Boc-Asn-Aib-Thr-Aib-OMe, was synthesized as a peptide model for the N-glycosylation site in N-glycoproteins.	Nitrogen	109-110	ANIB1	Homo sapiens	28-31
2489100-1	1989	A tetrapetide containing an Aib residue, Boc-Asn-Aib-Thr-Aib-OMe, was synthesized as a peptide model for the N-glycosylation site in N-glycoproteins.	Nitrogen	109-110	ANIB1	Homo sapiens	49-52
2489100-1	1989	A tetrapetide containing an Aib residue, Boc-Asn-Aib-Thr-Aib-OMe, was synthesized as a peptide model for the N-glycosylation site in N-glycoproteins.	Nitrogen	109-110	ANIB1	Homo sapiens	49-52
31373757-6	2019	Combining different approaches on three human colon cell lines (HT29, HCT116 and CCD841CoN), it is herein reported that silencing O-GlcNAc transferase (OGT, the sole enzyme driving O-GlcNAcylation), only slightly affects overall N- and O-glycosylation patterns.	Nitrogen	89-90	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	130-150
2478297-3	1989	A non-N-glycosylated form of SY generated by site-directed mutagenesis showed the same behavior and specific distribution in small vesicles.	Nitrogen	6-7	synaptophysin	Homo sapiens	29-31
31373757-6	2019	Combining different approaches on three human colon cell lines (HT29, HCT116 and CCD841CoN), it is herein reported that silencing O-GlcNAc transferase (OGT, the sole enzyme driving O-GlcNAcylation), only slightly affects overall N- and O-glycosylation patterns.	Nitrogen	89-90	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	152-155
31736755-11	2019	However, sustained treatment with DMA inhibited the adipocyte differentiation in both 3T3-L1 and C2C12 cells, and significantly lowered the expression of adipocyte markers, in particular, fatty acid-binding protein 4 (fabp4).	Nitrogen	34-37	fatty acid binding protein 4, adipocyte	Mus musculus	188-216
2477227-11	1989	We propose that the N-linked oligosaccharides on beta-core closely resemble the underlying N-linked structures of hCG beta with the antennary sialic acid, galactose, and N-acetylglucosamine removed.	Nitrogen	20-21	chorionic gonadotropin subunit beta 3	Homo sapiens	114-122
2554575-7	1989	Other characteristics, such as the potential N-glycosylation sites of protein NS1 and a potential proteolytic cleavage site within protein NS4B, are conserved within the mosquito-borne group, but differ in the TBE virus sequence.	Nitrogen	45-46	influenza virus NS1A binding protein	Homo sapiens	78-81
2775232-2	1989	CNBr cleavage of GPIIb, together with tryptic or endoproteinase Lys-C digestion of some of the isolated CNBr peptides, followed by amino acid and N-terminal sequence analysis of the isolated fragments, allowed us to locate unambiguously all the unknown disulphide bonds and the N-glycosylation points in platelet GPIIb.	Nitrogen	1-2	integrin subunit alpha 2b	Homo sapiens	17-22
31736755-11	2019	However, sustained treatment with DMA inhibited the adipocyte differentiation in both 3T3-L1 and C2C12 cells, and significantly lowered the expression of adipocyte markers, in particular, fatty acid-binding protein 4 (fabp4).	Nitrogen	34-37	fatty acid binding protein 4, adipocyte	Mus musculus	218-223
2775232-5	1989	The N-linked glycosylation points found here in platelet GPIIb are the same as the five N-glycosylated asparagine residues suggested after cDNA sequencing of human erythroleukaemic-cell GPIIb [Poncz, Eisman, Heindenreich, Silver, Vilaire, Surrey, Schwartz &amp; Bennett (1987) J. Biol.	Nitrogen	4-5	integrin subunit alpha 2b	Homo sapiens	57-62
2775232-5	1989	The N-linked glycosylation points found here in platelet GPIIb are the same as the five N-glycosylated asparagine residues suggested after cDNA sequencing of human erythroleukaemic-cell GPIIb [Poncz, Eisman, Heindenreich, Silver, Vilaire, Surrey, Schwartz &amp; Bennett (1987) J. Biol.	Nitrogen	4-5	integrin subunit alpha 2b	Homo sapiens	186-191
2775232-5	1989	The N-linked glycosylation points found here in platelet GPIIb are the same as the five N-glycosylated asparagine residues suggested after cDNA sequencing of human erythroleukaemic-cell GPIIb [Poncz, Eisman, Heindenreich, Silver, Vilaire, Surrey, Schwartz &amp; Bennett (1987) J. Biol.	Nitrogen	88-89	integrin subunit alpha 2b	Homo sapiens	57-62
31695625-5	2019	ITM2B is a ubiquitously expressed, N-glycosylated transmembrane regulatory protein, involved in familial dementias and retinal dystrophy; the function of TMEM85 is less defined.	Nitrogen	35-36	integral membrane protein 2B	Homo sapiens	0-5
2548482-0	1989	The role of N-linked glycosylation in the regulation of activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and proliferation of SV40-transformed 3T3 cells.	Nitrogen	12-13	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	Mus musculus	68-115
31695625-6	2019	Using coimmunoprecipitation, we confirmed the physical interaction between ITM2B or TMEM85 and N-terminal GLUT9 isoforms (GLUT9a and GLUT9b) in transfected HEK 293T cells and Xenopus oocytes, wherein ITM2B but not TMEM85 inhibited GLUT9-mediated urate uptake.	Nitrogen	95-96	integral membrane protein 2B	Homo sapiens	75-80
31695625-7	2019	Additionally, co-expression of ITM2B with GLUT9 in oocytes inhibited N-glycosylation of GLUT9a more than GLUT9b and stimulated urate efflux by both isoforms.	Nitrogen	69-70	integral membrane protein 2B	Homo sapiens	31-36
2751988-2	1989	Normal mode calculations on 13-cis-retinal Schiff bases demonstrate that the C15-D rock and N-CLys stretch are strongly coupled for C = N-syn chromophores and weakly coupled for C = N-anti chromophores.	Nitrogen	0-1	synemin	Homo sapiens	138-141
2751988-2	1989	Normal mode calculations on 13-cis-retinal Schiff bases demonstrate that the C15-D rock and N-CLys stretch are strongly coupled for C = N-syn chromophores and weakly coupled for C = N-anti chromophores.	Nitrogen	92-93	synemin	Homo sapiens	138-141
31695625-8	2019	However, urate uptake by N-glycosylation and N-terminal deletion GLUT9 mutants was efficiently inhibited by ITM2B, indicating that neither N-glycosylation nor the N terminus is necessary for functional interaction of GLUT9 with ITM2B.	Nitrogen	25-26	integral membrane protein 2B	Homo sapiens	108-113
31695625-8	2019	However, urate uptake by N-glycosylation and N-terminal deletion GLUT9 mutants was efficiently inhibited by ITM2B, indicating that neither N-glycosylation nor the N terminus is necessary for functional interaction of GLUT9 with ITM2B.	Nitrogen	45-46	integral membrane protein 2B	Homo sapiens	108-113
31695625-8	2019	However, urate uptake by N-glycosylation and N-terminal deletion GLUT9 mutants was efficiently inhibited by ITM2B, indicating that neither N-glycosylation nor the N terminus is necessary for functional interaction of GLUT9 with ITM2B.	Nitrogen	45-46	integral membrane protein 2B	Homo sapiens	108-113
31695625-8	2019	However, urate uptake by N-glycosylation and N-terminal deletion GLUT9 mutants was efficiently inhibited by ITM2B, indicating that neither N-glycosylation nor the N terminus is necessary for functional interaction of GLUT9 with ITM2B.	Nitrogen	45-46	integral membrane protein 2B	Homo sapiens	108-113
2568902-1	1989	Recent studies from our laboratory have shown relatively high levels of polymorphic N-acetyltransferase (NAT)(EC 2.3.1.5) activity toward carcinogenic arylamines in urinary bladder cytosol of humans and in the inbred hamster model of the N-acetylation polymorphism.	Nitrogen	84-85	bromodomain containing 2	Homo sapiens	105-108
31635263-4	2019	The ELP-VEGF fusion protein was modified by adding a kidney-targeting peptide (KTP) to the N-terminus.	Nitrogen	91-92	nuclear receptor subfamily 5 group A member 1	Homo sapiens	4-7
31559991-1	2019	We report a pyrolysis-phosphorization approach to fabricate carbon nanotubes with embedded CoP nanoparticles (CoP/CNs) using ZIF-67 as a precursor for electrocatalytic nitrogen (N2) reduction to ammonia (NH3) under ambient conditions.	Nitrogen	168-176	caspase recruitment domain family member 16	Homo sapiens	91-94
30991525-4	1989	Cellulases (C1,Cx) and beta glucosidase production were produced using different ammonium salts as additional nitrogen sources to what the corn cobs contained.	Nitrogen	110-118	anthocyanin regulatory C1 protein	Zea mays	12-39
2701940-8	1989	A putative asparagine-linked N-glycosylation site which was conserved in the chicken vitellogenin II and the Xenopus laevis vitellogenin A2 gene, at the beginning of exon 23, is also present in vitellogenin III.	Nitrogen	29-30	vitellogenin A2 L homeolog	Xenopus laevis	124-139
31559991-1	2019	We report a pyrolysis-phosphorization approach to fabricate carbon nanotubes with embedded CoP nanoparticles (CoP/CNs) using ZIF-67 as a precursor for electrocatalytic nitrogen (N2) reduction to ammonia (NH3) under ambient conditions.	Nitrogen	168-176	caspase recruitment domain family member 16	Homo sapiens	110-113
31597268-11	2019	In addition, many miRNAs were predicted to target NLP genes, notably miR167a, miR167b, miR160, and miR167 that were previously shown to target five NAC genes, including NAC1 and CUC1, under N-limited conditions.	Nitrogen	21-22	protein ATAF2	Gossypium hirsutum	169-173
2493149-1	1989	The opaque-2 gene was shown years ago to increase the nitrogen, lysine, and tryptophan contents of maize and to markedly increase its nutritional value for small children.	Nitrogen	54-62	regulatory protein opaque-2	Zea mays	4-12
31503487-2	2019	Complex 1 is protonated on the noncoordinating nitrogen of the hydrazonepyridine moiety to yield the active catalyst Zn(HL1)OAc (2) upon addition of acetic acid.	Nitrogen	47-55	intelectin 1	Homo sapiens	120-123
2783613-2	1989	The corresponding tetrahydroindenopyridine in which the double bond beta,gamma to the nitrogen atom retains allylic character is a somewhat better MAO-B substrate.	Nitrogen	86-94	monoamine oxidase B	Rattus norvegicus	147-152
2783613-3	1989	The steric bulk of the nitrogen and methylene bridges in addition to ring strain present in the proposed carbon-centered radical intermediates derived from these types of tricyclic structures may contribute to their relatively poor MAO-B substrate properties.	Nitrogen	23-31	monoamine oxidase B	Rattus norvegicus	232-237
2546731-3	1989	It has been established that pretreatment of NK-cells with culture medium from highly malignant cells and containing PGE, causes a sharp inhibition of their CTA, which is accompanied by an essential decrease of the ADA activity and an increase of the 5"-N activity in these cells as compared with the control.	Nitrogen	45-46	adenosine deaminase	Homo sapiens	215-218
31589603-5	2019	BMP signalling appears to regulate ecdysone receptor (EcR) levels via one or more mechanisms involving the EcR"s N terminus or the RNA sequence that encodes it.	Nitrogen	113-114	decapentaplegic	Drosophila melanogaster	0-3
2557733-0	1989	The trophic responses of avian sensory ganglia in vitro to N-acetylated and des-acetyl forms of alpha-melanocyte stimulating hormone (alpha-MSH) are qualitatively distinct.	Nitrogen	59-60	proopiomelanocortin	Rattus norvegicus	134-143
2557733-7	1989	The response to acetylated (N-acetyl, N,O-diacetyl) forms of alpha-MSH was characterized by fascicle formation by neurites which resulted in an apparent decrease in the neurite score, and by the outgrowth of non-neuronal cells.	Nitrogen	28-29	proopiomelanocortin	Rattus norvegicus	61-70
3198605-4	1988	The major portions of both h-lamp-1 and h-lamp-2 reside on the luminal side of the lysosome and are heavily glycosylated by N-glycans: h-lamp-1 and h-lamp-2 were found to contain 19 and 16 potential N-glycosylation sites, respectively.	Nitrogen	124-125	lysosomal associated membrane protein 2	Homo sapiens	42-48
3198605-4	1988	The major portions of both h-lamp-1 and h-lamp-2 reside on the luminal side of the lysosome and are heavily glycosylated by N-glycans: h-lamp-1 and h-lamp-2 were found to contain 19 and 16 potential N-glycosylation sites, respectively.	Nitrogen	124-125	lysosomal associated membrane protein 2	Homo sapiens	150-156
31582762-8	2019	In both model systems loss of ADPGK function led to defective N- and O-glycosylation.	Nitrogen	62-63	ADP-dependent glucokinase	Danio rerio	30-35
3198605-8	1988	These N-glycosylation sites are clustered into two domains separated by a hinge-like structure enriched with proline and serine in h-lamp-1 or proline and threonine in h-lamp-2.	Nitrogen	6-7	lysosomal associated membrane protein 2	Homo sapiens	170-176
3167672-3	1988	During hypoxia (10% O2 and nitrogen), however, both substances caused a significant reduction in PVR (p less than 0.05) without affecting SVR.	Nitrogen	27-35	PVR cell adhesion molecule	Canis lupus familiaris	97-100
31582762-9	2019	Overall, our data illustrate that ADPGK is part of a glucose sensing system in the ER modulating metabolism via regulation of N- and O-glycosylation.	Nitrogen	126-127	ADP-dependent glucokinase	Danio rerio	34-39
31573509-3	2019	In the human sHSP HSPB1, the disordered N-terminal region (NTR) represents nearly 50% of the sequence.	Nitrogen	40-41	heat shock protein family B (small) member 1	Homo sapiens	18-23
3345617-0	1988	Pharmacogenetics of N-methylation: heritability of human erythrocyte histamine N-methyltransferase activity.	Nitrogen	20-21	histamine N-methyltransferase	Homo sapiens	69-98
31548691-5	2019	Thus, Shh inactivates PTCH1 by grasping its extracellular domain with two lipidic pincers, the N-terminal palmitate and the C-terminal cholesterol, which are both inserted into the PTCH1 protein core.	Nitrogen	95-96	sonic hedgehog signaling molecule	Homo sapiens	6-9
3077896-8	1988	GH injection also resulted in a net retention of N during treatment, followed by a transient period of net N loss.	Nitrogen	49-50	somatotropin	Ovis aries	0-2
3077896-8	1988	GH injection also resulted in a net retention of N during treatment, followed by a transient period of net N loss.	Nitrogen	107-108	somatotropin	Ovis aries	0-2
31575075-3	2019	We confirm that DDX3X nuclear export is mediated by the nuclear transporter exportin-1/CRM1, dependent on an N-terminal, leucine-rich nuclear export signal (NES) and the monomeric guanine nucleotide binding protein Ran in activated GTP-bound form.	Nitrogen	109-110	exportin 1	Homo sapiens	76-86
2822381-8	1987	Nitrogen dioxide oxidizes oxyhemoglobin to methemoglobin and nitrite, yielding the autocatalytic phase.	Nitrogen	0-8	hemoglobin subunit gamma 2	Homo sapiens	43-56
31575075-3	2019	We confirm that DDX3X nuclear export is mediated by the nuclear transporter exportin-1/CRM1, dependent on an N-terminal, leucine-rich nuclear export signal (NES) and the monomeric guanine nucleotide binding protein Ran in activated GTP-bound form.	Nitrogen	109-110	exportin 1	Homo sapiens	87-91
31465212-4	2019	Both single and double O atom uptake at the chalcogens led to the conversion of the four-membered ring core, Ni(mu-EPhX)(mu-S"N2)Fe, to a five-membered ring Ni-O-E-Fe-S", where an O atom inserts between E and Ni.	Nitrogen	124-128	epoxide hydrolase 1	Homo sapiens	115-119
3651384-6	1987	The derived SGP-2 sequence has a molecular weight of 51,379 and contains six potential N-glycosylation sites.	Nitrogen	87-88	clusterin	Rattus norvegicus	12-17
31667125-4	2019	The truncation of the ACAT1 N-terminal dimerization domain, Delta1-65, creates a dimer which is fully enzymatically active.	Nitrogen	28-29	acetyl-CoA acetyltransferase 1	Homo sapiens	22-27
31607862-8	2019	In particular, expression of the N-terminal exons 1-12, but not the more C-terminal exons 19-22, was observed to increase in Shank3B mice with deletion of exons 13-16.	Nitrogen	33-34	SH3 and multiple ankyrin repeat domains 3	Mus musculus	125-132
3552673-2	1987	The NPR1 gene codes for a protein, called the nitrogen permease reactivator protein or Npr1, which appears to promote the activity of several permeases for nitrogenous substances under conditions of nitrogen catabolite derepression, but fails to do so in the presence of ammonium ions.	Nitrogen	46-54	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	4-8
3552673-2	1987	The NPR1 gene codes for a protein, called the nitrogen permease reactivator protein or Npr1, which appears to promote the activity of several permeases for nitrogenous substances under conditions of nitrogen catabolite derepression, but fails to do so in the presence of ammonium ions.	Nitrogen	46-54	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	87-91
3552673-6	1987	On nitrogen-derepressing media, NPR1 gene dose can be increased from 1 copy in a diploid to 16 plasmid-borne copies in a haploid strain without altering general amino-acid permease activity.	Nitrogen	3-11	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	32-36
3552673-9	1987	We hypothesize that this product inactivates the permease by stoichiometric binding and that the Npr1 protein or a product of its catalytic action opposes this binding under conditions of nitrogen derepression.	Nitrogen	188-196	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	97-101
31315432-5	2019	Notably, MFAP4 (microfibril-associated glycoprotein 4) showed increased and more diverse N-glycosylation in patients with MFS compared with control patients.	Nitrogen	0-1	microfibril associated protein 4	Homo sapiens	16-53
3325876-4	1987	Like the v-sis gene product, the PDGF-2 precursor undergoes N-linked glycosylation, implying its processing through the endoplasmic reticulum.	Nitrogen	60-61	platelet derived growth factor subunit B	Homo sapiens	33-39
31301181-1	2019	In the present work, we described convenient methods for the synthesis of N-thiophosphorylated 3-(4-aminophenyl)-coumarin-7-O-sulfamates as steroid sulfatase (STS) inhibitors.	Nitrogen	74-75	steroid sulfatase	Homo sapiens	140-157
2427577-3	1986	The 74,000 Mr erythrocyte DAF was lowered 3000 by endoglycosidase F, whereas endoglycosidase H had no effect, indicating one N-linked complex-type unit.	Nitrogen	125-126	CD55 molecule (Cromer blood group)	Homo sapiens	26-29
3517854-7	1986	Bovine IL-2 is unique among IL-2 homologs in that it has a single N-linked glycosylation site.	Nitrogen	66-67	interleukin 2	Bos taurus	28-32
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	139-140	complement C3	Homo sapiens	65-68
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	139-140	complement C9	Homo sapiens	75-78
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	145-146	complement C3	Homo sapiens	65-68
3079908-3	1986	We propose a stereochemical model in which the oxygens in TPA at C-3, C-4, C-9, and C-20 (O-3, O-4, O-9, and O-20) correspond to the O-11, N-13, N-1, and O-24 positions in teleocidin and the O-27, O-3, O-11, and O-30 oxygens in aplysiatoxin, respectively.	Nitrogen	145-146	complement C9	Homo sapiens	75-78
31328875-0	2019	Bio-Derived Co2 P Nanoparticles Supported on Nitrogen-Doped Carbon as Promising Oxygen Reduction Reaction Electrocatalyst for Anion Exchange Membrane Fuel Cells.	Nitrogen	45-53	complement C2	Homo sapiens	12-15
4093242-8	1985	These collective data suggest that PRG is composed of a disordered polypeptide chain with at least three of the N-linked Asn residues participating in some type of beta-turn.	Nitrogen	112-113	proline rich protein BstNI subfamily 3	Homo sapiens	35-38
31328875-8	2019	This excellent ORR activity and durability is attributable to the synergistic effect between Co2 P nanoparticles and nitrogen-doped carbon.	Nitrogen	117-125	complement C2	Homo sapiens	93-96
4027974-0	1985	Tissue nitrogen-sparing effect of high protein diet in mice with or without ascites tumor treated with Acinetobacter glutaminase-asparaginase.	Nitrogen	7-15	histocompatibility 40	Mus musculus	34-38
4027974-7	1985	The observed nitrogen-sparing effects of the high protein: energy ratio may be relevant to humans and to other forms of neoplasia and chemotherapy.	Nitrogen	13-21	histocompatibility 40	Mus musculus	45-49
3921831-9	1985	The finding that, following irradiation under anoxia, post-treatment with O2 (versus that with N2), also lowers the mutation frequency in mei-9 males, indicates that the repair defect in mei-9 does not interfere with oxygen-dependent post-radiation repair.	Nitrogen	95-97	meiotic 9	Drosophila melanogaster	138-143
3919005-8	1985	The comparison of the properties of 6-FPLP-reconstituted and native phosphorylases implies that the ring nitrogen of the coenzyme PLP in phosphorylase may interact with the protein during catalysis, and this interaction is important for efficient catalysis by phosphorylase.	Nitrogen	105-113	proteolipid protein 1	Homo sapiens	39-42
3882649-10	1985	Treatment of swine with pGH significantly decreased plasma blood urea nitrogen.	Nitrogen	70-78	somatotropin	Sus scrofa	24-27
6477553-4	1984	These results support the glutamine synthetase - glutamate synthase pathway for nitrogen assimilation.	Nitrogen	80-88	glutamine synthetase	Solanum lycopersicum	26-46
6522183-2	1984	More precisely, TBPA serves as a valid marker for determining both protein nutritional adequacy and the optimal ratio of energy and zinc to nitrogen intake in healthy newborns and preterm infants without infection.	Nitrogen	140-148	transthyretin	Homo sapiens	16-20
6733593-1	1984	Substituents on the nitrogen atom of the phosphorylcholine moiety of natural C16 platelet-activating factor (PAF) were modified or replaced by more bulky groups, and their hypotensive activities were examined with rats.	Nitrogen	20-28	PCNA clamp associated factor	Rattus norvegicus	109-112
6363106-1	1984	The temperature-sensitive S. cerevisiae mutant alg1-1, defective in the N-glycosylation of proteins, shows a first cycle arrest at the non-permissive temperature of 36 degrees C. The cell number increases by 50% and the absorbance approximately doubles.	Nitrogen	72-73	alpha-1,2-mannosyltransferase ALG11	Saccharomyces cerevisiae S288C	47-53
6329894-5	1984	The relation of frequency of the metastases to primary tumour staging (TNM) shows a 63% rate of metastases in patients with No and 86% in patients with N+.	Nitrogen	152-154	teneurin transmembrane protein 1	Homo sapiens	71-74
6688252-7	1983	There are three N-glycosylation sites, and this offers an explanation for the larger molecular size (Mr = 26,000-40,000) of natural mouse interferon-beta in comparison to the deduced interferon polypeptide.	Nitrogen	16-17	interferon beta 1, fibroblast	Mus musculus	138-153
6300058-7	1983	Functional CRP appeared to be required for all three responses observed after cyclic AMP addition: an abrupt step-up in the cellular rate of glycogen synthesis, a continuing exponential increase in rate, and a stimulation of the rate during a subsequent nitrogen starvation.	Nitrogen	254-262	catabolite gene activator protein	Escherichia coli	11-14
6138251-6	1983	This rather peculiar localization of glutamine synthetase demonstrates an interesting aspect of liver zonation and might have important implications for liver glutamine and, more generally, nitrogen metabolism.	Nitrogen	190-198	glutamate-ammonia ligase	Rattus norvegicus	37-57
2478590-6	1989	As a result, NA1 FcR III has only four potential N-linked glycosylation sites as compared with six in NA2 FcR III.	Nitrogen	13-14	Fc gamma receptor IIIa	Homo sapiens	17-24
2478590-7	1989	The amino acid substitutions and differences in the number of potential N-linked glycosylation sites probably account for the different forms of neutrophil FcR III observed after digestion with N-glycanase and for the antigenic heterogeneity of this receptor.	Nitrogen	72-73	Fc gamma receptor IIIa	Homo sapiens	156-163
2547451-4	1989	Both the MNP-PAPC and MNP-AA spin adducts showed some restriction of rotational motion when in the liposome bilayer (rotational correlation times 0.72 and 0.69.10(-9) s, respectively), and nitrogen hyperfine coupling constants (14.94-14.96 G) consistent with a hydrophobic localization.	Nitrogen	189-197	protocadherin 8	Homo sapiens	13-17
2547451-4	1989	Both the MNP-PAPC and MNP-AA spin adducts showed some restriction of rotational motion when in the liposome bilayer (rotational correlation times 0.72 and 0.69.10(-9) s, respectively), and nitrogen hyperfine coupling constants (14.94-14.96 G) consistent with a hydrophobic localization.	Nitrogen	189-197	spindlin 1	Homo sapiens	29-33
2779057-2	1989	In this method, the embryos were directly frozen in liquid nitrogen (LN2) vapor at approximately -170 degrees C for 2 min before being plunged into LN2.	Nitrogen	59-67	NZ lupus nephritis 2	Mus musculus	69-72
2563998-6	1989	glnA and glnII insertion mutants were glutamine prototrophs, lacked the respective GS form (GSI or GSII), grew normally on different nitrogen sources (Asm+), and induced normal, nitrogen-fixing nodules on Medicago sativa plants (Nod+ Fix+).	Nitrogen	133-141	glnA	Sinorhizobium meliloti	0-4
2563998-6	1989	glnA and glnII insertion mutants were glutamine prototrophs, lacked the respective GS form (GSI or GSII), grew normally on different nitrogen sources (Asm+), and induced normal, nitrogen-fixing nodules on Medicago sativa plants (Nod+ Fix+).	Nitrogen	178-186	glnA	Sinorhizobium meliloti	0-4
2918319-2	1989	The deduced amino acid sequence possesses characteristics expected of a nAChR subunit that does not bind acetylcholine, in addition to distinctive features such as unique cysteine residues and N-linked glycosylation sites.	Nitrogen	193-194	cholinergic receptor nicotinic beta 1 subunit	Rattus norvegicus	72-77
2918503-0	1989	Quinazoline antifolate thymidylate synthase inhibitors: nitrogen, oxygen, sulfur, and chlorine substituents in the C2 position.	Nitrogen	56-64	thymidylate synthase	Mus musculus	23-43
2559883-3	1989	Nitrosylhemoglobin shows a characteristic electron spin resonance (ESR) signal due to an odd electron localized on the nitrogen atom of NO and reacts with oxygen to yield nitrate and methemoglobin, which is rapidly reduced by methemoglobin reductase in red cells.	Nitrogen	119-127	hemoglobin subunit gamma 2	Homo sapiens	183-196
2559883-3	1989	Nitrosylhemoglobin shows a characteristic electron spin resonance (ESR) signal due to an odd electron localized on the nitrogen atom of NO and reacts with oxygen to yield nitrate and methemoglobin, which is rapidly reduced by methemoglobin reductase in red cells.	Nitrogen	119-127	hemoglobin subunit gamma 2	Homo sapiens	226-239
2492036-7	1989	Further studies in nitrogen mustard-treated animals revealed a suppression of the LVMI-stimulated increase in atrial FMLP receptor number.	Nitrogen	19-27	fMet-Leu-Phe receptor	Oryctolagus cuniculus	117-130
2909744-3	1989	Investigation of structure-activity relationships revealed that PAF antagonist activity is strongly influenced by the acyl substituent of the nitrogen atom on the carbamoyl group and the nature of the polar head group at the 3-position of the glycerin backbone.	Nitrogen	142-150	PCNA clamp associated factor	Rattus norvegicus	64-67
6402691-11	1983	The enhanced yields of recessive lethals with mei-9 females (after irradiation of the males either in air or in nitrogen) has been interpreted on the assumption that the mei-9 mutant is also deficient for the repair of X-ray-induced, recessive lethal-generating premutational lesions.	Nitrogen	112-120	meiotic 9	Drosophila melanogaster	170-175
7064898-8	1982	The only indicator correlating positively with nitrogen deficit was a fall in complement C3 (r = 0.87).	Nitrogen	47-55	complement C3	Homo sapiens	78-91
2494430-3	1989	t-PA expressed in Sf9 cells was both N glycosylated and secreted.	Nitrogen	37-38	chromosome 20 open reading frame 181	Homo sapiens	0-4
31466384-0	2019	Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation.	Nitrogen	66-67	endoglin	Homo sapiens	0-8
2494430-7	1989	This suggests that the mammalian signal sequence of t-PA is efficiently recognized in Sf9 cells and that it can mediate rapid translocation across the membrane of the rough endoplasmic reticulum, where cotranslational N glycosylation takes place.	Nitrogen	218-219	chromosome 20 open reading frame 181	Homo sapiens	52-56
2494430-10	1989	This suggests that N glycosylation per se, but not processing of the N-linked oligosaccharides, is required directly or indirectly in baculovirus-infected Sf9 cells for the secretion of t-PA.	Nitrogen	19-20	chromosome 20 open reading frame 181	Homo sapiens	186-190
2465204-3	1988	In this paper we present data on the GDH specific activities using both excess and limiting concentrations of ammonia as nitrogen sources.	Nitrogen	121-129	glutamate dehydrogenase	Escherichia coli	37-40
7035172-0	1982	Pleiotropic deficiency in nitrogen-uptake systems and derepression of nitrogen-catabolic enzymes in npr-1 mutants of Saccharomyces cerevisiae.	Nitrogen	70-78	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	100-105
7035172-3	1982	On the other hand, the activity of several ammonia-sensitive permeases is decreased (from 50-100% depending on the permease considered) in npr-1 cells, independently of the nitrogen source used for growth.	Nitrogen	173-181	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	139-144
7035172-4	1982	Our results favour the idea that the primary effect of the npr-1 mutation is on the permeases, and that the derepression of the enzymes is a consequence of the reduced uptake rate of the repressing nitrogen compounds.	Nitrogen	198-206	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	59-64
7035172-5	1982	Hence, the product of the npr-1 gene appears to be directly involved in the development of the activity of a set of permeases which transport nitrogen compounds and which are regulated by nitrogen effectors.	Nitrogen	142-150	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	26-31
7035172-5	1982	Hence, the product of the npr-1 gene appears to be directly involved in the development of the activity of a set of permeases which transport nitrogen compounds and which are regulated by nitrogen effectors.	Nitrogen	188-196	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	26-31
31602272-3	2019	In our present study, we found that the high expression of AIB1 was frequent detected in specimens of cervical cancer patients, and this was significantly correlated with CRT response (P = 0.014), clinical stage (P = 0.003), T status (P = 0.027), N status (P = 0.021), M status (P = 0.015) and progression-free survival (P &lt; 0.001).	Nitrogen	247-248	HEAT repeat containing 6	Homo sapiens	59-63
7287622-8	1981	Spirochete MA-2 did not require branched-chain amino acids for growth, but these compounds could serve as sole sources of nitrogen for the organism.	Nitrogen	122-130	PNMA family member 2	Homo sapiens	11-15
7279985-0	1981	New N-substituted derivatives of E-2"- and E-3"- hydroxystilbazoles-(4) of potential antimicrobial activity.	Nitrogen	0-1	cystatin 12, pseudogene	Homo sapiens	33-36
3141784-1	1988	The importance of carbohydrate in the secretion of immunoglobulin A (IgA) has previously been suggested by results of studies with tunicamycin, which prevents N-linked glycosylation of all cell glycoproteins.	Nitrogen	159-160	immunoglobulin heavy constant alpha	Mus musculus	51-73
31266804-10	2019	These results expand the targets of TMEM208-mediated ER translocation to include multipass transmembrane proteins and suggest that TRPC6 N-glycosylation plays multiple roles in modulating channel trafficking and activity.	Nitrogen	137-138	transmembrane protein 208	Homo sapiens	36-43
31393126-8	2019	Two N-glycosylation sites (N177 and N394), 3 sites (N145, N178, and N92), and 1 site of N183 were identified in MRJP1, MRJP2, and MRJP3, respectively.	Nitrogen	4-5	major royal jelly protein 2	Apis mellifera	119-124
3062558-7	1988	In the F1.8-group nitrogen excretion was higher, 138 mg/kg/day.	Nitrogen	18-26	mastermind like domain containing 1	Homo sapiens	7-11
3415241-13	1988	P-450 UT-7 had the highest N-demethylation activity.	Nitrogen	27-28	cytochrome P450, family 2, subfamily d, polypeptide 1	Rattus norvegicus	0-10
7400057-7	1980	Urinary nitrogen excretion was lower (P &lt; .01) in wethers receiving the F-CBG + glucose treatment than in those receiving the F-CBG treatment (3.60 vs 5.09 g/day).	Nitrogen	8-16	glucosylceramidase beta 3 (gene/pseudogene)	Homo sapiens	77-80
11219850-3	1980	There was rotation about the glycosyl bond and preference for either the anti or syn conformation depended on whether or not the 8-arylamino nitrogen was acetylated.	Nitrogen	141-149	synemin	Homo sapiens	81-84
31296534-0	2019	Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.	Nitrogen	79-80	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	52-57
226705-0	1979	Synthesis and biological properties of N2-substituted spin-labeled analogues of actinomycin D.	Nitrogen	39-41	spindlin 1	Mus musculus	54-58
2456763-6	1988	These findings strongly suggest that N-PTK is a specific kinase that phosphorylates pp60c-src and regulates its function in the cell.	Nitrogen	37-38	SRC proto-oncogene, non-receptor tyrosine kinase	Rattus norvegicus	84-93
2967760-5	1988	The transmembrane orientation of the TcR chains and of CD 3 gamma and CD 3 delta can be directly inferred from their primary structure, based on the presence of concensus N-linked glycosylation sites N-terminal of their transmembrane domains.	Nitrogen	171-172	CD3 gamma subunit of T-cell receptor complex	Homo sapiens	55-65
2831375-4	1988	One of the gag-pol and env clones (GP+E-86) was able to transfer G418 resistance to recipient cells at a titer of as high as 1.7 X 10(5) when it was used to package delta neo and as high as 4 X 10(6) when it was used to package N2.	Nitrogen	228-230	endogenous retrovirus group K member 20	Homo sapiens	23-26
2964755-5	1988	Also conserved were two signals for N-linked glycosylation located near the middle of NS-1.	Nitrogen	36-37	influenza virus NS1A binding protein	Homo sapiens	86-90
508303-2	1979	The spectrum of cytochrome b-563 at temperature of liquid N2 showed a single asymmetrical alpha-band with a maximum at 561 nm.	Nitrogen	58-60	mitochondrially encoded cytochrome b	Homo sapiens	16-28
31296534-0	2019	Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.	Nitrogen	79-80	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	63-68
39113-1	1979	Glutamine synthetase in Bacillus subtilis 168 was repressed to a greater extent by L-glutamine or L-arginine than by ammonia when each was used as sole nitrogen source.	Nitrogen	152-160	glutamine synthetase	Bacillus subtilis subsp. subtilis str. 168	0-20
31582880-9	2019	According to our results, the N-terminal kinase domain of RIPK4 is responsible for KRT14-RIPK4 interaction; however, the RIPK4 kinase activity is dispensable for the interaction.	Nitrogen	30-31	keratin 14	Homo sapiens	83-88
3207946-4	1988	Neither N [1-34] or C [35-84] terminal hormonal fragments were phosphorylated, suggesting that the structure of the intact PTH molecule is required for recognition by the enzyme.	Nitrogen	0-1	parathyroid hormone	Bos taurus	123-126
31943962-6	2019	Owing to the good light absorption of g-C3 N4 and the excellent catalytic activity of the Pd species, the g-C3 N4 /Pd shows an excellent photocatalytic performance in Suzuki coupling reactions with a TOF of 47.3 h-1 , which is almost twice that of a commercial homogeneous catalyst Pd(PPh3 )4 , under thermal heating.	Nitrogen	43-45	protein phosphatase 4 catalytic subunit	Homo sapiens	285-289
3359559-2	1988	Treatment with PB or CCl4 with the dosage and schedules employed proved to be effective in markedly modifying the N-demethylation of the three dimethyltriazenes tested, as had been determined in vitro.	Nitrogen	114-115	chemokine (C-C motif) ligand 4	Mus musculus	21-25
218622-3	1979	CRP modified with oPDM retains [3H]cAMP binding activity but loses [3H]d(I-C)n binding activity.	Nitrogen	28-29	catabolite gene activator protein	Escherichia coli	0-3
31943962-6	2019	Owing to the good light absorption of g-C3 N4 and the excellent catalytic activity of the Pd species, the g-C3 N4 /Pd shows an excellent photocatalytic performance in Suzuki coupling reactions with a TOF of 47.3 h-1 , which is almost twice that of a commercial homogeneous catalyst Pd(PPh3 )4 , under thermal heating.	Nitrogen	111-113	protein phosphatase 4 catalytic subunit	Homo sapiens	285-289
3275533-9	1988	Reactivity of purified USP-1 to various lectins and carbohydrate composition analysis suggested that USP-1 possesses biantennary N-linked complex-type carbohydrate chain with fucose.	Nitrogen	129-130	ubiquitin specific peptidase 1	Rattus norvegicus	23-28
3275533-9	1988	Reactivity of purified USP-1 to various lectins and carbohydrate composition analysis suggested that USP-1 possesses biantennary N-linked complex-type carbohydrate chain with fucose.	Nitrogen	129-130	ubiquitin specific peptidase 1	Rattus norvegicus	101-106
31213504-0	2019	Sit4 and PP2A Dephosphorylate Nitrogen Catabolite Repression-Sensitive Gln3 When TorC1 Is Up- as Well as Downregulated.	Nitrogen	30-38	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	0-4
3121434-2	1987	In the put3-75 mutant, the basal level of expression (ammonia as nitrogen source) of PUT1-lacZ and PUT2-lacZ gene fusions as measured by beta-galactosidase activity is reduced 4- and 7-fold, respectively, compared with the wild-type strain.	Nitrogen	65-73	Put3p	Saccharomyces cerevisiae S288C	7-11
429482-4	1979	hGH-S was more potent than hGH-I, as measured by nitrogen and potassium retention, and the differences reached levels of statistical significance.	Nitrogen	49-57	GHS	Homo sapiens	0-5
31213504-0	2019	Sit4 and PP2A Dephosphorylate Nitrogen Catabolite Repression-Sensitive Gln3 When TorC1 Is Up- as Well as Downregulated.	Nitrogen	30-38	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	71-75
3626536-5	1987	TTR, TF, and RBP correlated significantly with TB and NTB VIS nitrogen and TB CAR nitrogen.	Nitrogen	62-70	transthyretin	Rattus norvegicus	0-3
3626536-6	1987	The correlation of NTB VIS nitrogen with TTR, TF, and RBP (r range = 0.70-0.85, P less than 0.001) was higher than for TB rats (r range = 0.53-0.57, P less than 0.005).	Nitrogen	27-35	transthyretin	Rattus norvegicus	41-44
31213504-5	2019	Two of TorC1"s many downstream targets are Gln3 and Gat1-GATA-family transcription activators-whose localization and function are Nitrogen Catabolite Repression- (NCR-) sensitive.	Nitrogen	130-138	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	43-47
3626536-7	1987	The correlation of TB carcass nitrogen (r range = 0.47-0.51, P less than 0.01) with TTR, TF, and RBP was higher than for NTB carcass nitrogen which was not significant (r range = 0.25-0.37, P less than 0.57).	Nitrogen	30-38	transthyretin	Rattus norvegicus	84-87
3626536-8	1987	These data indicate that TTR, TF, and RBP do correlate with components of body nitrogen mass, but factors other than nutrition may influence their metabolism in the TB host.	Nitrogen	79-87	transthyretin	Rattus norvegicus	25-28
77750-0	1978	Haptenic antibody induced by N-phthaloylated ox insulin in the Hartley guinea-pig.	Nitrogen	29-30	insulin	Cavia porcellus	48-55
77750-1	1978	Female Hartley guinea-pigs were immunized with N-phthaloylated ox insulin (96% NA1,NB1,NB29-triphthaloyl ox insulin) using H. pertussis as adjuvant.	Nitrogen	47-48	insulin	Cavia porcellus	66-73
31213504-6	2019	In nitrogen replete environments, TorC1 is activated, thereby inhibiting the PTap42-Sit4 and PTap42-PP2A (Pph21/Pph22-Tpd3, Pph21,22-Rts1/Cdc55) phosphatase complexes.	Nitrogen	3-11	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	84-88
3816802-6	1987	In contrast to GPIb alpha, which is very rich in O-linked oligosaccharides, sugar analysis revealed that GPIb beta and GP17 seem to have only N-linked chains of the lactosamine type.	Nitrogen	142-143	glycoprotein Ib platelet subunit beta	Homo sapiens	105-114
31213504-6	2019	In nitrogen replete environments, TorC1 is activated, thereby inhibiting the PTap42-Sit4 and PTap42-PP2A (Pph21/Pph22-Tpd3, Pph21,22-Rts1/Cdc55) phosphatase complexes.	Nitrogen	3-11	protein phosphatase 2A regulatory subunit RTS1	Saccharomyces cerevisiae S288C	133-137
31213504-6	2019	In nitrogen replete environments, TorC1 is activated, thereby inhibiting the PTap42-Sit4 and PTap42-PP2A (Pph21/Pph22-Tpd3, Pph21,22-Rts1/Cdc55) phosphatase complexes.	Nitrogen	3-11	protein phosphatase 2A regulatory subunit CDC55	Saccharomyces cerevisiae S288C	138-143
31213504-8	2019	In nitrogen-limiting conditions, TorC1 is downregulated and PTap42-Sit4 and PTap42-PP2A are active.	Nitrogen	3-11	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	67-71
413891-5	1978	The drop in the hepatic glycogen level and the unusually long daylight period of sustained GP and PEPCK activities in separately-fed rats consuming the protein meal at 09:00 hours suggests that, in this case, part of the ingested nitrogen could have been catabolized and used for gluconeogenesis, thus explaining our previous observation of lower nitrogen retention observed in this group of rats.	Nitrogen	230-238	phosphoenolpyruvate carboxykinase 1	Rattus norvegicus	98-103
31213504-10	2019	A paradoxical observation, however, led us to suspect that Gln3 control was more complex than appreciated, i.e., Sit4 dephosphorylates Gln3 more in excess than in limiting nitrogen conditions.	Nitrogen	172-180	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	59-63
24414267-6	1978	However, the disappearance of lipase activity from the cotyledons after fat utilization was found to depend on nitrogen nutrition of the seedlings.	Nitrogen	111-119	lipase-like	Brassica napus	30-36
3328221-11	1987	Detailed studies of Cu(II) and Ni(II) binding to albumin suggests that both metals have the same specific binding site at the NH2-terminal tripeptide sequence (Asp1-Ala2-His3...) involving the Asp alpha-NH2, His3 N (1) imidazole, two deprotonated peptide nitrogens (Ala2NH and His3NH), and Asp1 COO- group.	Nitrogen	255-264	beta-secretase 2	Homo sapiens	160-164
3790162-3	1986	Our results have shown that the N-demethylation of benzphetamine was progressively inhibited in cytochrome b5-fortified microsomal preparations.	Nitrogen	32-33	cytochrome b5 type A	Rattus norvegicus	96-109
31213504-10	2019	A paradoxical observation, however, led us to suspect that Gln3 control was more complex than appreciated, i.e., Sit4 dephosphorylates Gln3 more in excess than in limiting nitrogen conditions.	Nitrogen	172-180	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	113-117
16660146-0	1977	Glutamate synthase: a possible role in nitrogen metabolism of the developing maize endosperm.	Nitrogen	39-47	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	0-18
31117816-11	2019	Given that LDL-C was also reduced in a group of clinically unaffected heterozygotes, we propose that increasing LDL receptor-mediated cholesterol clearance by targeting N-glycosylation in the LDL pathway may represent a novel therapeutic strategy to reduce LDL-C and cardiovascular disease.	Nitrogen	169-170	low density lipoprotein receptor	Homo sapiens	112-124
16660146-6	1977	Maximum glutamate synthase activity was the order of 56 nmoles of glutamate formed per minute per endosperm compared with a rate of N accumulation of 9.5 nmoles per minute.It is suggested that glutamate synthase plays a key role in the N nutrition of the maize endosperm providing a means whereby N transported in the form of glutamine is made available for the synthesis of other seed protein amino acids via transaminase reactions.	Nitrogen	132-133	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	193-211
16660146-6	1977	Maximum glutamate synthase activity was the order of 56 nmoles of glutamate formed per minute per endosperm compared with a rate of N accumulation of 9.5 nmoles per minute.It is suggested that glutamate synthase plays a key role in the N nutrition of the maize endosperm providing a means whereby N transported in the form of glutamine is made available for the synthesis of other seed protein amino acids via transaminase reactions.	Nitrogen	236-237	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	8-26
16660146-6	1977	Maximum glutamate synthase activity was the order of 56 nmoles of glutamate formed per minute per endosperm compared with a rate of N accumulation of 9.5 nmoles per minute.It is suggested that glutamate synthase plays a key role in the N nutrition of the maize endosperm providing a means whereby N transported in the form of glutamine is made available for the synthesis of other seed protein amino acids via transaminase reactions.	Nitrogen	236-237	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	193-211
16660146-6	1977	Maximum glutamate synthase activity was the order of 56 nmoles of glutamate formed per minute per endosperm compared with a rate of N accumulation of 9.5 nmoles per minute.It is suggested that glutamate synthase plays a key role in the N nutrition of the maize endosperm providing a means whereby N transported in the form of glutamine is made available for the synthesis of other seed protein amino acids via transaminase reactions.	Nitrogen	236-237	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	8-26
16660146-6	1977	Maximum glutamate synthase activity was the order of 56 nmoles of glutamate formed per minute per endosperm compared with a rate of N accumulation of 9.5 nmoles per minute.It is suggested that glutamate synthase plays a key role in the N nutrition of the maize endosperm providing a means whereby N transported in the form of glutamine is made available for the synthesis of other seed protein amino acids via transaminase reactions.	Nitrogen	236-237	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	193-211
3757943-1	1986	The first step in metabolic activation of mutagenic and carcinogenic heterocyclic amines has been elucidated to be N-hydroxylation by cytochrome P-448.	Nitrogen	115-116	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	145-150
3729411-0	1986	N-demethylation of N-nitrosodimethylamine catalyzed by purified rat hepatic microsomal cytochrome P-450: isozyme specificity and role of cytochrome b5.	Nitrogen	0-1	cytochrome b5 type A	Rattus norvegicus	137-150
31051313-7	2019	The molecular docking and activity experiments indicated that the N-methyl substitution on the side chain of these drugs played a significant role in activating MRGPRX2, while the phenothiazine tricyclic ring was associated with the inhibiting effect on the H1R.	Nitrogen	66-67	histamine receptor H1	Mus musculus	258-261
3758192-4	1986	Our present and previous data suggest that N exemplifies one class of anabolic steroids that become less androgenic due to 5 alpha-reduction, it shows high myotropic activity, M-A dissociation (= 7-30) and affinity to the androgen receptor.	Nitrogen	43-44	androgen receptor	Rattus norvegicus	222-239
778498-3	1976	Hg elevation of PaO2 was usually observed and respiratory distress was reduced, as compared to results obtained with nitrogen-oxygen CPAP.	Nitrogen	117-125	centromere protein J	Homo sapiens	133-137
778498-5	1976	Therefore, He-CPAP is recommendable for intermediate respiratory support between mechanical ventilation and nitrogen-oxygen CPAP.	Nitrogen	108-116	centromere protein J	Homo sapiens	14-18
778498-5	1976	Therefore, He-CPAP is recommendable for intermediate respiratory support between mechanical ventilation and nitrogen-oxygen CPAP.	Nitrogen	108-116	centromere protein J	Homo sapiens	124-128
31036724-8	2019	The present study demonstrates the presence of complicated regulatory mechanisms of GDH mediated by multiple compounds to control the carbon-nitrogen balance in bacterial cells.IMPORTANCE GDH, which catalyzes the synthesis and degradation of glutamate using NAD(P)(H), is a widely distributed enzyme among all domains of life.	Nitrogen	141-149	glutamate dehydrogenase 1	Homo sapiens	84-87
4154-4	1975	Detailed kinetic investigation of the hydrolysis of acetylcholine by acetylcholinesterase in the presence of modifiers shows that the effects produced by numerous quaternary nitrogen compounds on the enzyme can be explained on the basis of binding of the effectors to the anionic subsite of the active center.	Nitrogen	174-182	acetylcholinesterase	Bos taurus	69-89
1055171-1	1975	Complement receptor activity for cell bound C3b and C3d was detected on plasma membrane fragments prepared by nitrogen cavitation from cultured human lymphoid cells.	Nitrogen	110-118	complement C3	Homo sapiens	44-47
1139004-2	1975	Substitution of methyl groups of the ammonium grouping with other radicals and incorporation of onium nitrogen in the cycle resulted in the decrease of the hydrolysis rate under the action of BCE and ACE, the effect of BCE being more pronounced.	Nitrogen	102-110	acetylcholinesterase	Bos taurus	200-203
3086086-9	1986	Synaptophysin is N-glycosylated, since cultivation of the rat phaeochromocytoma cell line PC12 in the presence of tunicamycin reduced its mol.	Nitrogen	17-18	synaptophysin	Rattus norvegicus	0-13
4062295-4	1985	Reduction of methemoglobin is optimally observed under nitrogen since, in the presence of oxygen, reduced divicine undergoes autoxidation.	Nitrogen	55-63	hemoglobin subunit gamma 2	Homo sapiens	13-26
31036724-8	2019	The present study demonstrates the presence of complicated regulatory mechanisms of GDH mediated by multiple compounds to control the carbon-nitrogen balance in bacterial cells.IMPORTANCE GDH, which catalyzes the synthesis and degradation of glutamate using NAD(P)(H), is a widely distributed enzyme among all domains of life.	Nitrogen	141-149	glutamate dehydrogenase 1	Homo sapiens	188-191
2993748-10	1985	This result indicates that the potentiating effects of N-POMC derived peptides on the steroidogenic effect of ACTH which has been described on rat and human adrenal, is not a general phenomenon in mammals.	Nitrogen	55-56	proopiomelanocortin	Rattus norvegicus	57-61
805658-1	1975	By taking advantage of the structural requirements of the substrates for prostatic acid phosphatase (PAP), which consist of steric hindrance and the presence of basic nitrogen in the molecule, potential cytotoxic agents (spindle poisons) are being designed that will become enzyme activated specifically by PAP.	Nitrogen	167-175	acid phosphatase 3	Homo sapiens	73-99
805658-1	1975	By taking advantage of the structural requirements of the substrates for prostatic acid phosphatase (PAP), which consist of steric hindrance and the presence of basic nitrogen in the molecule, potential cytotoxic agents (spindle poisons) are being designed that will become enzyme activated specifically by PAP.	Nitrogen	167-175	acid phosphatase 3	Homo sapiens	101-104
3933178-2	1985	It was noted that C3 and C9 were particularly sensitive to protein deficiency in the diet (5 to 8.2 g/day according to nitrogen), with the titers of these fractions being low.	Nitrogen	119-127	complement C3	Homo sapiens	18-27
4554497-0	1972	Microsomal N-oxidation of dapson as a cause of methemoglobin formation in human red cells.	Nitrogen	11-12	hemoglobin subunit gamma 2	Homo sapiens	47-60
31036724-13	2019	This suggests that T. thermophilus possesses a complicated regulatory mechanism of GDH to control carbon and nitrogen metabolism.	Nitrogen	109-117	glutamate dehydrogenase 1	Homo sapiens	83-86
31101650-7	2019	Collectively, our findings show that STT3A-dependent inhibition of N-linked glycosylation on receptor tyrosine kinases and their convertases combines to impair receptor processing and surface localization.	Nitrogen	67-68	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	37-42
4675358-0	1972	[Effect of textured soy bean protein on nitrogen balance in man].	Nitrogen	40-48	brain expressed associated with NEDD4 1	Homo sapiens	24-28
2990531-8	1985	The 53 ppm downfield shift upon the addition of substrate along with 1H NMR data suggests that one oxygen ligand to Cd2+ in the binary complex is replaced by a nitrogen ligand at some intermediate point in the enzymic reaction.	Nitrogen	160-168	T-cell surface antigen CD2	Oryctolagus cuniculus	116-119
30998272-4	2019	More significantly, the correlation between N dopants and interlayer distance of resultant N-FLG-T highlights the effect of pyrrolic N on the enlargement of graphene interlayer spacing, due to its stronger electrostatic repulsion.	Nitrogen	44-45	filaggrin	Homo sapiens	93-96
2981876-3	1985	There are two N-linked glycosylated intermediate precursor forms (apparent Mr = 35,000 (p35) and 37,000 (p37].	Nitrogen	14-15	interleukin 12A	Homo sapiens	88-91
5441070-0	1970	Effects of certain nitrogen mustards upon the progression of cultured H.Ep.	Nitrogen	19-27	DNL-type zinc finger	Homo sapiens	70-74
20184461-0	1967	Total nitrogen content of human duodenal juice before and after intravenous injection of secretin.	Nitrogen	6-14	secretin	Homo sapiens	89-97
20184461-1	1967	The property of secretin to alter the total nitrogen content of duodenal juice was evaluated in 27 patients.	Nitrogen	44-52	secretin	Homo sapiens	16-24
20184461-2	1967	The mean concentration of total nitrogen was about 100 ml of duodenal juice before secretin stimulation and dropped to about the half after secretin.	Nitrogen	32-40	secretin	Homo sapiens	83-91
30998272-4	2019	More significantly, the correlation between N dopants and interlayer distance of resultant N-FLG-T highlights the effect of pyrrolic N on the enlargement of graphene interlayer spacing, due to its stronger electrostatic repulsion.	Nitrogen	91-92	filaggrin	Homo sapiens	93-96
20184461-2	1967	The mean concentration of total nitrogen was about 100 ml of duodenal juice before secretin stimulation and dropped to about the half after secretin.	Nitrogen	32-40	secretin	Homo sapiens	140-148
6487743-3	1984	Values of amino pKD fall in the range 8.6-9.4 for the unsubstituted nucleobases and their endocyclic N-methylated derivatives.	Nitrogen	101-102	protein kinase D1	Homo sapiens	16-19
20184461-3	1967	In patients with pathological values of volume or bicarbonate concentration after secretin injection, the decrease in total nitrogen concentration following stimulation was significantly less.	Nitrogen	124-132	secretin	Homo sapiens	82-90
30998272-5	2019	As a consequence, N-FLG-800 achieves the optimal properties in terms of interlayer spacing, nitrogen configuration and electronic conductivity.	Nitrogen	92-100	filaggrin	Homo sapiens	20-23
20184461-8	1967	After stimulation a slighter significant correlation only was found between the concentrations of total nitrogen and total protein in the first 20-minute post-secretin period.	Nitrogen	104-112	secretin	Homo sapiens	159-167
30998272-6	2019	When used as an anode for SIBs, N-FLG-800 shows remarkable Na+ storage performance with ultrahigh rate capability (56.6 mAh g-1 at 40 A g-1 ) and excellent long-term stability (211.3 mAh g-1 at 0.5 A g-1 after 2000 cycles), demonstrating the effectiveness of material design.	Nitrogen	32-33	filaggrin	Homo sapiens	34-37
30916964-1	2019	We have generated Lennard-Jones potentials for the interaction between CX2 (X = O, S) and 11 nitrogen-doped benzene derivatives in different orientations at the M06-2X/def2-tzvpp level as tools to parametrize accurate force fields and to better understand the interaction of these greenhouse gases with heterocyclic building blocks used in the design of capture and detection systems.	Nitrogen	93-101	interleukin 17C	Homo sapiens	71-74
5872154-2	1965	The influence of nitrogen at high pressure on chromosome adhesiveness after irradiation of infiltrated bean seedlings].	Nitrogen	17-25	brain expressed associated with NEDD4 1	Homo sapiens	103-107
6491679-2	1984	The chemical shift of H-14 was found to be a reliable indicator of the orientation of the N-methyl group.	Nitrogen	90-91	H1.4 linker histone, cluster member	Homo sapiens	22-26
6734034-4	1984	Smokers had higher Clm to all metabolites, particularly by the N-demethylation pathways.	Nitrogen	63-64	cystatin 9	Homo sapiens	19-22
31026140-2	2019	Here, in situ growth of mullite SmMn2O5 on nitrogen-doped reduced graphene oxide (SMO@NrGO) is achieved for highly efficient oxygen reduction reaction (ORR).	Nitrogen	43-51	smoothened, frizzled class receptor	Homo sapiens	82-85
13714174-2	1961	The effects of various chemical compounds on the nitrogen mustard (HN1)-induced changes in enzyme activities of certain tissues of rats.	Nitrogen	49-57	Jupiter microtubule associated homolog 1	Rattus norvegicus	67-70
6139720-3	1983	The mechanism of the utilization of glutamine as catalyzed by gamma-glutamyl transpeptidase, involves the formation of a gamma-glutamyl enzyme bound intermediate as the initial step, with release of the amide nitrogen as ammonium, NH+4, Figure 1.	Nitrogen	209-217	inactive glutathione hydrolase 2	Homo sapiens	62-91
14427015-0	1959	[Studies on certain effects of human STH on urinary steroids and on nitrogen metabolism in a patient with hypophysial infantilism].	Nitrogen	68-76	saitohin	Homo sapiens	37-40
30885034-0	2019	The Pat1-Lsm complex prevents 3" to 5" degradation of a specific subset of ATG mRNAs during nitrogen starvation-induced autophagy.	Nitrogen	92-100	amyloid beta precursor protein binding protein 2	Homo sapiens	4-8
13835778-0	1959	[Proteolytic activity of Actinomyces streptomycini Kras, and its relation to the form of nitrogen in culture media].	Nitrogen	89-97	KRAS proto-oncogene, GTPase	Homo sapiens	51-55
18858640-1	1948	Nitrogen mustards are powerful inhibitors for choline oxidase, acetylcholine esterase, and choline acetylase, half-inhibition of the first enzyme being produced with concentrations around 1 x 10(-6)M; i.e., ten times less than the LD(50) values.	Nitrogen	0-8	choline O-acetyltransferase	Homo sapiens	91-108
16652548-0	1928	NITROGEN METABOLISM IN THE SOY BEAN.	Nitrogen	0-8	brain expressed associated with NEDD4 1	Homo sapiens	31-35
6357979-2	1983	The purpose of this work was to investigate insulin receptors in growing ruminant sheep given a control diet or undergoing nitrogen restriction.	Nitrogen	123-131	LOC105613195	Ovis aries	44-51
6849870-6	1983	The neighboring negative side chains in the peptide sequence also suggest that the single positive charge present on the piperazine nitrogens of trifluoperazine may interact with them and sterically block a region of interaction of calmodulin (CaM) and troponin C (TnC) with modulated proteins such as phosphodiesterase.	Nitrogen	132-141	tenascin	Oryctolagus cuniculus	253-263
6849870-6	1983	The neighboring negative side chains in the peptide sequence also suggest that the single positive charge present on the piperazine nitrogens of trifluoperazine may interact with them and sterically block a region of interaction of calmodulin (CaM) and troponin C (TnC) with modulated proteins such as phosphodiesterase.	Nitrogen	132-141	tenascin	Oryctolagus cuniculus	265-268
6402691-7	1983	Irradiation in air or in nitrogen led to significantly higher yields of recessive lethals when the irradiated males were mated to mei-9 females, whereas, after irradiation in oxygen, the yields were similar with both kinds of female.	Nitrogen	25-33	meiotic 9	Drosophila melanogaster	130-135
16662738-8	1982	At 36 days after pollination, less N had accumulated in the grain of the opaque-2 genotype, but otherwise there were no differences in N contents or dry weights of the shoots due to the opaque-2 gene.	Nitrogen	35-36	regulatory protein opaque-2	Zea mays	73-81
30885034-3	2019	In a recent study we showed that, during nitrogen starvation, the RNA-binding complex Pat1-Lsm is involved in binding and preventing the 3" to 5" exosome-mediated degradation of a specific subset of ATG mRNAs.	Nitrogen	41-49	amyloid beta precursor protein binding protein 2	Homo sapiens	86-90
33840589-9	2021	IL-6 and IL-10 were closely associated with white blood cells, neutrophils, T lymphocyte subsets, D-D dimer, blood urea nitrogen, complement C1q, procalcitonin C-reactive protein.	Nitrogen	120-128	interleukin 10	Homo sapiens	9-14
31019315-3	2019	The transition-metal-catalysed reduction of nitrogen gas2-6 is an alternative method for the formation of ammonia.	Nitrogen	44-52	growth arrest specific 2	Homo sapiens	53-59
33870613-3	2021	Deletion of Dsk2 resulted in mild growth defect on scant media with various carbon/nitrogen sources and dramatic attenuation in conidiation capability at optimal condition.	Nitrogen	83-91	ubiquitin domain-containing protein DSK2	Saccharomyces cerevisiae S288C	12-16
6757722-10	1982	Synthesis of the five enzymes produced constitutively in dal80-1-containing mutants remains normally sensitive to nitrogen repression even though the dal80-1 mutation is present.	Nitrogen	114-122	Dal80p	Saccharomyces cerevisiae S288C	57-62
7104383-2	1982	Elastin concentration of the specimens was also estimated by hot alkali extraction followed by nitrogen determination of the extracted material and the insoluble residue.	Nitrogen	95-103	elastin	Homo sapiens	0-7
30923994-1	2019	Bacterial L-aspartate alpha-decarboxylase (PanD) is a potential biocatalyst for the green production of beta-alanine, an important block chemical for manufacturing nitrogen-containing chemicals in bio-refinery field.	Nitrogen	164-172	aspartate 1-decarboxylase	Corynebacterium jeikeium K411	43-47
6122575-9	1982	Indeed, strains bearing proteinase A, B and C mutations are no longer inactivated under nitrogen starvation.	Nitrogen	88-96	proteinase A	Saccharomyces cerevisiae S288C	24-36
34050740-4	2021	Unlike other nlp single mutants, nlp2 and nlp7 single mutants showed a reduction in shoot fresh weight when grown in the presence of nitrate as the sole nitrogen source, indicating that NLP2, like NLP7, plays a major role in vegetative growth.	Nitrogen	153-161	NIN like protein 7	Arabidopsis thaliana	42-46
33711100-4	2021	Interestingly, we demonstrated that WRKY33 upregulation triggers a higher expression of 21 genes cluster including other TFs, many of which related to N-metabolism, able to improve both NUE components.	Nitrogen	151-152	WRKY DNA-binding protein 33	Arabidopsis thaliana	36-42
30815666-0	2019	Theoretical study of single transition metal atom modified MoP as a nitrogen reduction electrocatalyst.	Nitrogen	68-76	opioid receptor mu 1	Homo sapiens	59-62
33711100-6	2021	Finally, a 35S::AtWRKY33 over expressing Arabidopsis transgenic line, that shows a more competitive root system more efficient to take up N from the soil, confirmed the pivotal role of WRKY33 for NUE improvement.	Nitrogen	138-139	WRKY DNA-binding protein 33	Arabidopsis thaliana	18-24
34030043-0	2021	The N-linked glycosylations of TIGIT Asn32 and Asn101 facilitate PVR/TIGIT interaction.	Nitrogen	4-5	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	31-36
6811357-0	1982	N-Hydroxylation enzymes of carcinogenic aminoazo dyes: possible involvement of cytochrome P-448.	Nitrogen	0-1	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	79-95
6811357-9	1982	From these results, it is concluded that, in addition to MFAO, cytochrome P-448 is involved in the N-hydroxylation of MAB.	Nitrogen	99-100	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	63-79
34030043-0	2021	The N-linked glycosylations of TIGIT Asn32 and Asn101 facilitate PVR/TIGIT interaction.	Nitrogen	4-5	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	69-74
30815666-6	2019	Therefore, Mn-MoP is a better catalyst to realize the nitrogen reduction reaction.	Nitrogen	54-62	opioid receptor mu 1	Homo sapiens	14-17
34030043-2	2021	Here we show that TIGIT N-glycosylations are critical for maintaining the interaction between TIGIT and PVR.	Nitrogen	24-25	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	18-23
34030043-2	2021	Here we show that TIGIT N-glycosylations are critical for maintaining the interaction between TIGIT and PVR.	Nitrogen	24-25	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	94-99
6756667-10	1982	These findings suggest that N-hydroxylation of OAT mainly proceeds via catalysis by cytochrome P-448 and that this process is an obligatory step for the activation of OAT.	Nitrogen	28-29	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	84-100
34030043-3	2021	TIGIT has two N-glycosylation residues, N32 and N101.	Nitrogen	14-15	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	0-5
31459646-0	2019	BCl3-Mediated C-N, C-S, and C-O Bond Formation of Imidazo[1,2-a]pyridine Benzylic Ethers.	Nitrogen	16-17	BCL3 transcription coactivator	Homo sapiens	0-4
34030043-4	2021	N-glycosylation on N101 of TIGIT and, to less extent, on N32, play potent roles in PVR binding.	Nitrogen	0-1	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	27-32
34030043-5	2021	Taken together, these findings suggest that the N-glycosylation sites on TIGIT, especially residue N101, may be potential targets for PVR/TIGIT immune checkpoint blockade.	Nitrogen	48-49	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	73-78
34030043-5	2021	Taken together, these findings suggest that the N-glycosylation sites on TIGIT, especially residue N101, may be potential targets for PVR/TIGIT immune checkpoint blockade.	Nitrogen	48-49	T cell immunoreceptor with Ig and ITIM domains	Homo sapiens	138-143
7110435-5	1982	For estimation of these parameters it is necessary to calculate the n and p at two different Ca2+ ion concentrations.	Nitrogen	13-14	carbonic anhydrase 2	Homo sapiens	93-96
6271833-4	1981	Introduction of a weakly basic nitrogen at C-5 and deletion of the axial methyl group in the B ring, two structural changes forbidden by traditional cannabinoid SAR, resulted in a unique family of benzoquinolines with potent analgetic activity.	Nitrogen	31-39	sarcosine dehydrogenase	Homo sapiens	161-164
6786888-13	1981	The structure of the N-glycosidically-linked chain was NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 6)[NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 3)]Man(beta 1 leads to 4)GlcNAc(beta 1 leads to 4)[Fuc alpha 1 leads to 6]GlcNAc leads to Asn.	Nitrogen	21-22	galanin and GMAP prepropeptide	Homo sapiens	61-115
6786888-13	1981	The structure of the N-glycosidically-linked chain was NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 6)[NeuAc(alpha 2 leads to 6)Gal(beta 1 leads to 4)GlcNAc(beta 1 leads to 2)Man(alpha 1 leads to 3)]Man(beta 1 leads to 4)GlcNAc(beta 1 leads to 4)[Fuc alpha 1 leads to 6]GlcNAc leads to Asn.	Nitrogen	21-22	galanin and GMAP prepropeptide	Homo sapiens	157-211
7195011-9	1981	It was observed that: i) n ranged from 0.2-0.5 and was higher the lower H, this inverse relationship being essentially due to the dependence of n on Hal as described by: Hal = Ho .	Nitrogen	25-26	histidine ammonia-lyase	Canis lupus familiaris	149-152
7195011-9	1981	It was observed that: i) n ranged from 0.2-0.5 and was higher the lower H, this inverse relationship being essentially due to the dependence of n on Hal as described by: Hal = Ho .	Nitrogen	25-26	histidine ammonia-lyase	Canis lupus familiaris	170-173
7195011-9	1981	It was observed that: i) n ranged from 0.2-0.5 and was higher the lower H, this inverse relationship being essentially due to the dependence of n on Hal as described by: Hal = Ho .	Nitrogen	29-30	histidine ammonia-lyase	Canis lupus familiaris	149-152
7195011-9	1981	It was observed that: i) n ranged from 0.2-0.5 and was higher the lower H, this inverse relationship being essentially due to the dependence of n on Hal as described by: Hal = Ho .	Nitrogen	29-30	histidine ammonia-lyase	Canis lupus familiaris	170-173
34054836-2	2021	In fish, IFNgamma stimulates the expression of cytokines and chemokines associated with the pro-inflammatory response and enhances the production of nitrogen and oxygen reactive species in phagocytic cells.	Nitrogen	149-157	interferon gamma	Salmo salar	9-17
33984360-7	2021	BECN1 levels showed a significantly positive correlation with coagulation markers such as D-dimer and Fibrinogen (FIB) and inflammation markers such as C-reactive protein (CRP), Procalcitonin (PCT), Ferritin and biochemical markers such as Blood urea nitrogen and Lactate dehydrogenase (p < 0.001).	Nitrogen	251-259	beclin 1	Homo sapiens	0-5
31245758-7	2019	By enriching glycoproteins in gsnor1-3 and mass spectrometry analysis, TGG2 (thioglucoside glucohydrolase2) was identified as one of co-substrates with high degradation rate and elevated N-glycosylation level in gsnor1-3 ost3/6.	Nitrogen	187-188	glucoside glucohydrolase 2	Arabidopsis thaliana	71-75
33650863-0	2021	Uromodulin Isolation and Its N-Glycosylation Analysis by NanoLC-MS/MS.	Nitrogen	29-30	uromodulin	Homo sapiens	0-10
33847125-0	2021	Electronic and Spin-State Effects on Dinitrogen Splitting to Nitrides in a Rhenium Pincer System.	Nitrogen	37-47	spindlin 1	Homo sapiens	15-19
6774978-5	1980	Five oligosaccharides (F1, G, H1, I, and J) were shown to have typical high-mannose type structures (Man alpha 1-)n.Man beta 1-4GlcNAc beta 1-GlcNAc, with n-values of 8, 7, 6, 5, and 4, respectively.	Nitrogen	38-39	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	120-126
6774978-5	1980	Five oligosaccharides (F1, G, H1, I, and J) were shown to have typical high-mannose type structures (Man alpha 1-)n.Man beta 1-4GlcNAc beta 1-GlcNAc, with n-values of 8, 7, 6, 5, and 4, respectively.	Nitrogen	38-39	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	135-141
30721035-3	2019	Various peculiar nitrogen polymerization forms composed of single/double nitrogen-nitrogen bonds were found at the nitrogen-rich condition, such as N -chains in P21/ m-SeN3, oligomeric N8-chains in P1-SeN4, and distorted N63- anion rings in P1-SeN5.	Nitrogen	17-25	H3 histone pseudogene 16	Homo sapiens	161-164
6247646-6	1980	It is calculated that the N-atoms of the two PLP-substituted lysines must be at a distance less than or equal to 12 A. Analysing our and literature data, one may suppose that Lys-13 and Lys-87 are the most probable candidates for modification with PLP.	Nitrogen	26-27	proteolipid protein 1	Homo sapiens	45-48
33949893-8	2021	RESULTS: Spontaneous preterm birth at 20-31 wk was increased in association with tap water nitrate concentrations during pregnancy of 5 to <10mg/L [odds ratio (OR)=1.47; 95% confidence interval (CI): 1.29, 1.67] and >=10mg/L (OR=2.52; 95% CI: 1.49, 4.26) compared with <5mg/L (as nitrogen).	Nitrogen	280-288	nuclear RNA export factor 1	Homo sapiens	81-84
33934458-7	2021	Our models predict that the Diatom/Dino ratio will further increase with increasing anthropogenic input and global warming in subtropical estuarine ecosystems with nitrate as the dominant inorganic nitrogen; its ecological consequences are worthy of further investigation.	Nitrogen	198-206	damage induced long noncoding RNA	Homo sapiens	35-39
6766929-4	1980	The absorption spectra of reduced OM cytochrome b and cytochrome b5 in the visible region at liquid nitrogen temperature showed small but significant differences between them.	Nitrogen	100-108	cytochrome b, mitochondrial	Rattus norvegicus	37-49
30721035-3	2019	Various peculiar nitrogen polymerization forms composed of single/double nitrogen-nitrogen bonds were found at the nitrogen-rich condition, such as N -chains in P21/ m-SeN3, oligomeric N8-chains in P1-SeN4, and distorted N63- anion rings in P1-SeN5.	Nitrogen	73-81	H3 histone pseudogene 16	Homo sapiens	161-164
6766929-4	1980	The absorption spectra of reduced OM cytochrome b and cytochrome b5 in the visible region at liquid nitrogen temperature showed small but significant differences between them.	Nitrogen	100-108	cytochrome b5 type A	Rattus norvegicus	54-67
30721035-3	2019	Various peculiar nitrogen polymerization forms composed of single/double nitrogen-nitrogen bonds were found at the nitrogen-rich condition, such as N -chains in P21/ m-SeN3, oligomeric N8-chains in P1-SeN4, and distorted N63- anion rings in P1-SeN5.	Nitrogen	73-81	H3 histone pseudogene 16	Homo sapiens	161-164
33947960-5	2021	In-depth mass spectrometry-based glycomic and glycoproteomic analysis of ErbB2"s ectodomain disclosed a site-specific glycosylation profile in GC cells, in which the ST6Gal1 sialyltransferase specifically targets ErbB2 N-glycosylation sites occurring within the receptor"s trastuzumab-binding domain.	Nitrogen	219-220	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	166-173
30721035-3	2019	Various peculiar nitrogen polymerization forms composed of single/double nitrogen-nitrogen bonds were found at the nitrogen-rich condition, such as N -chains in P21/ m-SeN3, oligomeric N8-chains in P1-SeN4, and distorted N63- anion rings in P1-SeN5.	Nitrogen	73-81	H3 histone pseudogene 16	Homo sapiens	161-164
30645113-4	2019	Structure-activity relationship studies revealed that incorporation of a nitrogen atom into the phenothiazine framework results in increased potency and selectivity for HDAC6 (more than 500-fold selectivity relative to the inhibition of HDAC1, HDAC4, and HDAC8), as rationalized by molecular modeling and docking studies.	Nitrogen	73-81	histone deacetylase 6	Danio rerio	169-174
33997033-8	2021	After control factors age, sex, and BMI, urinary CD163 levels in systemic vasculitis patients were positively correlated with serum creatinine, blood urea nitrogen, and beta-2 microglobulin (r = 0.45, 0.48, and 0.46; p = 0.001, 0.001, and 0.002, respectively).	Nitrogen	155-163	CD163 molecule	Homo sapiens	49-54
33935494-11	2021	Conclusion: Alendronate application partially reversed the suppression of expression of BMP2, EIF2AK3, EIF2A, ATF4 caused by liquid nitrogen.	Nitrogen	132-140	eukaryotic translation initiation factor 2A	Rattus norvegicus	94-99
17750321-1	1979	Nodulin-35, a 35,000-molecular-weight protein, is present in soybean root nodules developed by different strains of Rhizobium japonicum, irrespective of their effectiveness in fixing atmospheric nitrogen.	Nitrogen	195-203	uricase-2 isozyme 2	Glycine max	0-10
429482-7	1979	We conclude hGH-S, a two-chain form of hGH, caused significantly greater nitrogen and potassium retention in human subjects in short term balance studies than hGH-I.	Nitrogen	73-81	GHS	Homo sapiens	12-17
30754-10	1978	In addition, the pleiotropic growth of the mutants with elevated glutamine synthetase activities suggests that a nitrogen control response exists for S. typhimurium and that it can be altered by mutations affecting glutamine synthetase regulation.	Nitrogen	113-121	type I glutamate--ammonia ligase	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	65-85
30754-10	1978	In addition, the pleiotropic growth of the mutants with elevated glutamine synthetase activities suggests that a nitrogen control response exists for S. typhimurium and that it can be altered by mutations affecting glutamine synthetase regulation.	Nitrogen	113-121	type I glutamate--ammonia ligase	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	215-235
30645113-4	2019	Structure-activity relationship studies revealed that incorporation of a nitrogen atom into the phenothiazine framework results in increased potency and selectivity for HDAC6 (more than 500-fold selectivity relative to the inhibition of HDAC1, HDAC4, and HDAC8), as rationalized by molecular modeling and docking studies.	Nitrogen	73-81	histone deacetylase 1	Danio rerio	237-242
357955-0	1978	[The use of two nitrogen-washout tests as an indication for treatment of hyaline membrane disease with nasal-CPAP].	Nitrogen	16-24	centromere protein J	Homo sapiens	109-113
29969180-2	2019	Nicotiana benthamiana is widely used for the transient expression of recombinant proteins so it is desirable to modify the endogenous N-glycosylation machinery to allow the synthesis of complex N-glycans lacking beta-1,2-xylose and core alpha-1,3-fucose.	Nitrogen	0-1	adrenoceptor alpha 1D	Homo sapiens	237-246
938666-5	1976	It was found that ligament elastin purified by repeated autoclaving contains approximately 2.29 mumol of acid-labile amide nitrogen per 10 mg of protein, a value equivalent to approximately 70% of the total number of dicarboxylic amino acid residues.	Nitrogen	123-131	elastin	Homo sapiens	27-34
34025932-7	2021	We demonstrate that this allosteric network exists only in N-SH2, which is directly involved in the regulation of SHP2 activity, while the C-terminal SH2 domain (C-SH2) functions primarily to recruit high-affinity bidentate phosphopeptides.	Nitrogen	59-60	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	114-118
30058762-2	2019	In this article, a particular attention has been paid to the N- and O-glycosylation that characterize the alpha-L-iduronidase produced using this hairy root based system.	Nitrogen	61-62	alpha-L-iduronidase	Homo sapiens	106-125
33837215-3	2021	In this study, the first example of a nitrogen-rich hydrogen-bonded organic framework (HOF-NF) is designed and constructed through self-assembly in energetic materials, in which NF anions are trapped in pores of the resulting framework via the dual force of ionic and hydrogen bonds from the strengthened framework.	Nitrogen	38-46	neurofascin	Homo sapiens	91-93
33837215-3	2021	In this study, the first example of a nitrogen-rich hydrogen-bonded organic framework (HOF-NF) is designed and constructed through self-assembly in energetic materials, in which NF anions are trapped in pores of the resulting framework via the dual force of ionic and hydrogen bonds from the strengthened framework.	Nitrogen	38-46	neurofascin	Homo sapiens	178-180
30058762-4	2019	Indeed, on each of the 6 N-glycosylation sites of the IDUA, a single N-glycan composed of a core Man3 GlcNAc2 carrying one beta(1,2)-xylose and one alpha(1,3)-fucose epitope (M3XFGN2) was identified, highlighting the high homogeneity of the production system.	Nitrogen	25-26	alpha-L-iduronidase	Homo sapiens	54-58
782874-13	1976	This theory of the mode of action is further supported by the findings that injections of growth hormone closely resemble the effects of diethylstilbestrol on nitrogen retention and blood metabolites in sheep.	Nitrogen	159-167	somatotropin	Ovis aries	90-104
33750110-3	2021	Herein, a more reasonable molecular structure consisting of pyridinic/pyrrolic nitrogen (NPD/NPL) is proposed, based on the analysis of combined X-ray photoelectron spectroscopy, 13C/15N solid-state nuclear magnetic resonance, and density functional theory data.	Nitrogen	79-87	N-acetylneuraminate pyruvate lyase	Homo sapiens	93-96
30527663-0	2019	The Pat1-Lsm Complex Stabilizes ATG mRNA during Nitrogen Starvation-Induced Autophagy.	Nitrogen	48-56	amyloid beta precursor protein binding protein 2	Homo sapiens	4-8
33750110-4	2021	The coexistence of vicinal NPD/NPL entities plays a vital role in attracting S2 molecules and facilitating N-S bond formation apart from the generally accepted C-S bond in S-cPAN, which could explain the extraordinary electrochemical features of S-cPAN among various nitrogen-containing sulfurized polymers.	Nitrogen	27-28	N-acetylneuraminate pyruvate lyase	Homo sapiens	31-34
33750110-4	2021	The coexistence of vicinal NPD/NPL entities plays a vital role in attracting S2 molecules and facilitating N-S bond formation apart from the generally accepted C-S bond in S-cPAN, which could explain the extraordinary electrochemical features of S-cPAN among various nitrogen-containing sulfurized polymers.	Nitrogen	267-275	N-acetylneuraminate pyruvate lyase	Homo sapiens	31-34
4531004-2	1974	The enzyme, obtained in apparently homogeneous form (monomer molecular weight about 227,000; s(20,omega) = 17.6 S), was found to be a typical glutamine amidotransferase in that it exhibits glutaminase activity and can utilize ammonia in place of glutamine as a nitrogen donor.	Nitrogen	261-269	guanine monophosphate synthase	Homo sapiens	142-168
33157282-3	2021	Here, human erythropoietin fused to human IgG Fc (EPO-Fc) was co-expressed with N-acetyl-glucosaminyltransferase-IVa (GnT-IVa) by adenoviral transduction in goat mammary gland to evaluate the in vivo modification of N-glycosylation pattern in this tissue.	Nitrogen	80-81	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	118-125
4686241-0	1973	[Methemoglobin level in the population of villages surrounding an artificial nitrogen plant and exposed to air pollution].	Nitrogen	77-85	hemoglobin subunit gamma 2	Homo sapiens	1-14
30527663-3	2019	Under nitrogen-starvation conditions, Pat1-Lsm binds a specific subset of autophagy-related (ATG) transcripts and prevents their 3" to 5" degradation by the exosome complex, leading to ATG mRNA stabilization and accumulation.	Nitrogen	6-14	amyloid beta precursor protein binding protein 2	Homo sapiens	38-42
30527663-4	2019	This process is regulated through Pat1 dephosphorylation, is necessary for the efficient expression of specific Atg proteins, and is required for robust autophagy induction during nitrogen starvation.	Nitrogen	180-188	amyloid beta precursor protein binding protein 2	Homo sapiens	34-38
29967251-2	2019	We hypothesized that inhibition of protein N-linked glycosylation, an endoplasmic reticulum co- and posttranslational modification crucial for RTK maturation and activation, could provide a new therapeutic approach for glioma radiosensitization.Experimental Design: We investigated the effects of a small-molecule inhibitor of the oligosaccharyltransferase (NGI-1) on EGFR family receptors, MET, PDGFR, and FGFR1.	Nitrogen	43-44	ret proto-oncogene	Homo sapiens	143-146
5280529-4	1971	A critical role is played by the asparagine residue: its peptide N-H participates in the formation of the hydrogen-bonded cyclic structure of the beta-turn in the ring component of oxytocin and its peptide C=O can be hydrogen-bonded to the N-H of tyrosine, while its side chain C=O stabilizes the second beta-turn by forming a hydrogen bond with the N-H of the leucine residue, which is part of the end peptide of the second beta-turn.	Nitrogen	65-66	oxytocin/neurophysin I prepropeptide	Homo sapiens	181-189
5280529-4	1971	A critical role is played by the asparagine residue: its peptide N-H participates in the formation of the hydrogen-bonded cyclic structure of the beta-turn in the ring component of oxytocin and its peptide C=O can be hydrogen-bonded to the N-H of tyrosine, while its side chain C=O stabilizes the second beta-turn by forming a hydrogen bond with the N-H of the leucine residue, which is part of the end peptide of the second beta-turn.	Nitrogen	240-241	oxytocin/neurophysin I prepropeptide	Homo sapiens	181-189
28305072-2	1970	Injection of nitrogen mustard (HN-3) into late third instar larvae ofDrosophila melanogaster and treatment of male foreleg disks with HN-3in vitro results in the following: formation of fewer bristles and hairs, reduction in size of leg parts, alteration of normal bristle patterns, and differentiation of bristle organs without sockets and bracts.	Nitrogen	13-21	MT-RNR2 like 3 (pseudogene)	Homo sapiens	31-35
33750826-3	2021	Here, focusing on insect N-glycosylation, we characterized Bombyx mori N-acetylgalactosaminyltransferase (BmGalNAcT) participating in complex N-glycan biosynthesis in mammals.	Nitrogen	25-26	N-acetylgalactosaminyltransferase 7	Bombyx mori	106-115
33748605-1	2021	A type of carbon molecular sieve (CMS-3KT) was used as the adsorbent for the CH4 enrichment of a methane/oxygen/nitrogen (CH4/O2/N2) mixture using micro-positive pressure vacuum pressure swing adsorption (~120 kPa).	Nitrogen	112-120	immunoglobulin kappa variable 1D-39	Homo sapiens	122-131
33664400-2	2021	As a prime example of the significance of glycans, the ability of the cell surface receptor CD44 to bind its ligand, hyaluronan, is modulated by N-glycosylation.	Nitrogen	145-146	CD44 molecule (Indian blood group)	Homo sapiens	92-96
33664400-4	2021	Based on atomistic simulations and NMR, we provide evidence that CD44 has multiple distinct binding sites for hyaluronan, and that N-glycosylation modulates their respective roles.	Nitrogen	35-36	CD44 molecule (Indian blood group)	Homo sapiens	65-69
13372793-0	1956	Effects of small daily doses of growth hormone on nitrogen output in normal and depancreatized dogs.	Nitrogen	50-58	somatotropin	Canis lupus familiaris	32-46
30634395-7	2019	Sp1 translocation to the nuclei and its enhanced binding to the Snat3 promoter, along with Sp1 dependence of system N-mediated [3H]glutamine uptake, were observed in astrocytes upon ammonia exposure.	Nitrogen	116-117	solute carrier family 38, member 3	Mus musculus	64-69
34024545-10	2021	Low intakes of n-3 PUFA are present in a large proportion of the population.	Nitrogen	15-17	pumilio RNA binding family member 3	Homo sapiens	19-23
33412225-10	2021	CONCLUSIONS: ISM1 is C-mannosylated in its TSR domain, and the status of the C-mannosylation of ISM1 affects its N-glycosylation.	Nitrogen	2-3	isthmin 1	Homo sapiens	13-17
30735719-5	2019	Moreover, serum DMP1 concentrations were closely related to blood urea nitrogen, creatinine, cystatin C, and vascular endothelial growth factor (VEGF).	Nitrogen	71-79	dentin matrix acidic phosphoprotein 1	Homo sapiens	16-20
33412225-10	2021	CONCLUSIONS: ISM1 is C-mannosylated in its TSR domain, and the status of the C-mannosylation of ISM1 affects its N-glycosylation.	Nitrogen	2-3	isthmin 1	Homo sapiens	96-100
33412225-11	2021	GENERAL SIGNIFICANCE: The C-mannosylation of ISM1 regulates its N-glycosylation status.	Nitrogen	2-3	isthmin 1	Homo sapiens	45-49
34013717-0	2021	Fe/Fe3C Embedded in N-Doped Worm-like Porous Carbon for High-Rate Catalysis in Rechargeable Zinc-Air Batteries.	Nitrogen	20-21	general transcription factor IIE subunit 1	Homo sapiens	0-2
30267434-5	2019	TSA1 is N-glycosylated and localizes to the ER body as a luminal protein.	Nitrogen	8-9	tryptophan synthase alpha chain	Arabidopsis thaliana	0-4
34018219-3	2021	All that is exemplified by model calculations on 1D chain, 2D square lattice as well as on more realistic superconducting doped graphene, magnetic phases of iron, and spin-liquid and magnetically ordered states of a simplest nitrogen-based copper pseudo-oxide, CuNCN, resembling socalled metal-oxide framework (MOF) phases by the atomic interlinkage.	Nitrogen	225-233	spindlin 1	Homo sapiens	167-171
33637855-0	2021	Enhanced NRT1.1/NPF6.3 expression in shoots improves growth under nitrogen deficiency stress in Arabidopsis.	Nitrogen	66-74	nitrate transporter 1.1	Arabidopsis thaliana	9-15
33637855-0	2021	Enhanced NRT1.1/NPF6.3 expression in shoots improves growth under nitrogen deficiency stress in Arabidopsis.	Nitrogen	66-74	nitrate transporter 1.1	Arabidopsis thaliana	16-22
33637855-3	2021	Various analyses using accessions exhibiting reduced N deficiency responses revealed that enhanced NRT1.1 expression in shoots rather than in roots is responsible for better growth of Arabidopsis seedlings under N deficient conditions.	Nitrogen	53-54	nitrate transporter 1.1	Arabidopsis thaliana	99-105
30574022-0	2018	The role of N-glycosylation of CD200-CD200R1 interaction in classical microglial activation.	Nitrogen	12-13	CD200 molecule	Homo sapiens	31-36
33476158-1	2021	Relativistic density functional theory has been employed to characterize [AnO2(L)]0/-1 complexes, where An = U, Np, Pu, and Am, and L is the recently reported hexa-aza porphyrin analogue, termed dipyriamethyrin, which contains six nitrogen donor atoms (four pyrrolic and two pyridine rings).	Nitrogen	231-239	anoctamin 2	Homo sapiens	74-78
34019934-5	2021	The activation of AGEs-mediated RAGE could evoke nicotinamide adenine dinucleotide phosphate oxidase-induced reactive oxygen and nitrogen species production and subsequently give rise to oxidative stress in DKD and ageing kidney.	Nitrogen	129-137	advanced glycosylation end-product specific receptor	Homo sapiens	32-36
33962063-5	2021	QSOX1 both senses and regulates ROS levels through interaction with and redox-mediated regulation of S-nitrosoglutathione reductase that, consistent with previous findings, influences reactive nitrogen-mediated regulation of ROS generation.	Nitrogen	193-201	quiescin sulfhydryl oxidase 1	Homo sapiens	0-5
30348809-0	2018	A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia.	Nitrogen	2-3	colony stimulating factor 3 receptor	Homo sapiens	28-33
33962063-6	2021	Collectively, our data indicate that QSOX1 is a redox sensor that negatively regulates plant immunity by linking reactive oxygen- and reactive nitrogen-signaling to limit ROS production.	Nitrogen	143-151	quiescin sulfhydryl oxidase 1	Homo sapiens	37-42
33857131-7	2021	Next, the phosphorylation, N-glycosylation, and S-nitrosylation sites were predicted to characterize the innexin isoforms.	Nitrogen	0-1	pannexin 1	Homo sapiens	105-112
33497242-0	2021	Ship-in-a-Bottle Synthesis of High Concentration of N2 Molecules in a Cage-Structured Electride.	Nitrogen	52-54	inositol polyphosphate-5-phosphatase D	Homo sapiens	0-4
32815269-1	2021	On the demand of single-photon entangled light sources and high-sensitivity probes in the fields of quantum information processing, weak magnetic field detection and biosensing, the nitrogen vacancy (NV) color center is very attractive and has been deeply and intensively studied, due to its convenience of spin initialization, operation, and optical readout combined with long coherence time in the ambient environment.	Nitrogen	182-190	spindlin 1	Homo sapiens	307-311
33300232-1	2021	Signal sequence receptor protein 4 (SSR4) is a subunit of the translocon-associated protein (TRAP) complex, which participates in the translocation of proteins across the endoplasmic reticulum membrane, enhancing the efficiency of N-linked glycosylation.	Nitrogen	231-232	signal sequence receptor subunit 4	Homo sapiens	0-34
33300232-1	2021	Signal sequence receptor protein 4 (SSR4) is a subunit of the translocon-associated protein (TRAP) complex, which participates in the translocation of proteins across the endoplasmic reticulum membrane, enhancing the efficiency of N-linked glycosylation.	Nitrogen	231-232	signal sequence receptor subunit 4	Homo sapiens	36-40
33636666-6	2021	The reaction mechanisms of AAP with hydroxyl radical (HO ), reactive chlorine species (RCS), and reactive nitrogen species (RNS) were discussed in detail.	Nitrogen	106-114	serpin family F member 2	Homo sapiens	27-30
30348809-8	2018	Mutation of the N610 site prevented membrane-proximal N-glycosylation of CSF3R, which then drove ligand-independent cellular expansion.	Nitrogen	16-17	colony stimulating factor 3 receptor	Homo sapiens	73-78
33523898-0	2021	The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress.	Nitrogen	78-79	TRAP	Homo sapiens	35-39
33523898-2	2021	Here, we introduce a fluorescence-based strategy to detect aberrant N-glycosylation in individual cells and identify a regulatory role for the heterotetrameric translocon-associated protein (TRAP) complex.	Nitrogen	68-69	TRAP	Homo sapiens	191-195
33331147-6	2021	One compound, designated inhibitor 3, in which the backbone sulfur and terminal methyl group of RF036 were replaced by nitrogen and oxetane, respectively, had comparable activity, selectivity, and membrane permeability to RF036 while exhibiting greatly enhanced solubility and stability.	Nitrogen	119-127	protein phosphatase 1 regulatory inhibitor subunit 11	Homo sapiens	25-36
30348809-11	2018	SIGNIFICANCE: This study reveals the critical importance of membrane-proximal N-linked glycosylation of CSF3R for the maintenance of ligand dependency in leukemia.	Nitrogen	3-4	colony stimulating factor 3 receptor	Homo sapiens	104-109
33523898-3	2021	Unexpectedly, cells with knockout of SSR3 or SSR4 subunits restore N-glycosylation over time concurrent with a diminished ER stress transcriptional signature.	Nitrogen	67-68	signal sequence receptor subunit 3	Homo sapiens	37-41
33523898-3	2021	Unexpectedly, cells with knockout of SSR3 or SSR4 subunits restore N-glycosylation over time concurrent with a diminished ER stress transcriptional signature.	Nitrogen	67-68	signal sequence receptor subunit 4	Homo sapiens	45-49
33523898-4	2021	Activation of ER stress or silencing of the ER chaperone BiP exacerbates or rescues the glycosylation defects, respectively, indicating that SSR3 and SSR4 enable N-glycosylation during ER stress.	Nitrogen	162-163	signal sequence receptor subunit 3	Homo sapiens	141-145
30064091-1	2018	In this work, Ni modified Pd nanoparticles immobilized on hollow nitrogen doped carbon spheres were successfully prepared, denoted as Pd/Ni-N/C.	Nitrogen	65-73	ninein	Homo sapiens	137-143
33523898-4	2021	Activation of ER stress or silencing of the ER chaperone BiP exacerbates or rescues the glycosylation defects, respectively, indicating that SSR3 and SSR4 enable N-glycosylation during ER stress.	Nitrogen	162-163	signal sequence receptor subunit 4	Homo sapiens	150-154
33523898-5	2021	Protein levels of the SSR3 subunit are ER stress and UBE2J1 dependent, revealing a mechanism that coordinates upstream N-glycosylation proficiency with downstream ER-associated degradation and proteostasis.	Nitrogen	119-120	signal sequence receptor subunit 3	Homo sapiens	22-26
33537962-0	2021	Globalization of nitrogen deposition and ecosystem response: A 20-year perspective : This article belongs to Ambio"s 50th Anniversary Collection.	Nitrogen	17-25	immunoglobulin kappa variable 1-27	Homo sapiens	61-65
34012659-11	2021	We also observed the increased ER degradation-enhancing alpha-mannosidase-like protein 3 (EDEM3), which is trimming of N-linked glycans by sequential removal of mannose residues, might result in more non-N-glycosylated form of BST-2.	Nitrogen	119-120	bone marrow stromal cell antigen 2	Homo sapiens	227-232
34012659-12	2021	Moreover, we demonstrated that BST-2 and non-N-glycosylated BST-2 N65/92A mutant, not only enhanced the tumor characteristics of hepatoma cell lines in vitro, but also enhanced the growth of mouse xenografts in vivo.	Nitrogen	45-46	bone marrow stromal cell antigen 2	Mus musculus	60-65
34012659-15	2021	Conclusions: Our findings illuminate the novel function of BST-2 as an oncogene of HBV-associated HCC, and highlight the novel relationship of N-glycosylation of BST-2 in regulating HCC tumorigenesis in vitro.	Nitrogen	143-144	bone marrow stromal cell antigen 2	Homo sapiens	162-167
30471763-7	2018	In addition, N-glycosylation of CD147 has been identified as low glycosylated (approximately 32 kDa) or high glycosylated (approximately 45-65 kDa).	Nitrogen	13-14	basigin (Ok blood group)	Homo sapiens	32-37
33709701-1	2021	The stereospecific, substrate (nitrogen source)-controlled intermolecular anti- and syn-1,2-diaminations of unactivated alkenes using the same catalysis (an iodine catalyst) is reported.	Nitrogen	31-39	synapsin I	Homo sapiens	84-89
33411100-6	2021	Based on the GO and KEGG pathway analysis, the most important dysregulated pathways were regulation of cell proliferation, biocarbonate transport, Wnt, and IL-17 signaling pathways, and nitrogen metabolism.	Nitrogen	186-194	interleukin 17A	Homo sapiens	156-161
30487594-0	2018	Stable isotopic evidence of nitrogen sources and C4 metabolism driving the world"s largest macroalgal green tides in the Yellow Sea.	Nitrogen	28-36	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	128-131
31995179-8	2021	Doxorubicin increased myocardial MMP-2 activity in part also by upregulating N-terminal truncated MMP-2.	Nitrogen	77-78	matrix metallopeptidase 2	Mus musculus	33-38
31995179-8	2021	Doxorubicin increased myocardial MMP-2 activity in part also by upregulating N-terminal truncated MMP-2.	Nitrogen	77-78	matrix metallopeptidase 2	Mus musculus	98-103
33755986-4	2021	An overall increase in delta15 N of soil total N (delta15 NTN ) from 7.1 to 7.9% indicated accelerated and greater openness of soil N cycling that was also partially revealed by enhanced net N mineralization rates.	Nitrogen	31-32	neurturin	Homo sapiens	58-61
33755986-4	2021	An overall increase in delta15 N of soil total N (delta15 NTN ) from 7.1 to 7.9% indicated accelerated and greater openness of soil N cycling that was also partially revealed by enhanced net N mineralization rates.	Nitrogen	47-48	neurturin	Homo sapiens	58-61
33755986-4	2021	An overall increase in delta15 N of soil total N (delta15 NTN ) from 7.1 to 7.9% indicated accelerated and greater openness of soil N cycling that was also partially revealed by enhanced net N mineralization rates.	Nitrogen	47-48	neurturin	Homo sapiens	58-61
33755986-4	2021	An overall increase in delta15 N of soil total N (delta15 NTN ) from 7.1 to 7.9% indicated accelerated and greater openness of soil N cycling that was also partially revealed by enhanced net N mineralization rates.	Nitrogen	47-48	neurturin	Homo sapiens	58-61
31458237-6	2018	Both network PIMs displayed high theoretical ideal adsorbed solution theory CO2/N2 selectivities (51 and 94 at 273 K vs 34 and 84 at 298 K for MP1 and MP2, respectively).	Nitrogen	80-82	tryptase pseudogene 1	Homo sapiens	151-154
33412225-0	2021	Regulation of N-glycosylation and secretion of Isthmin-1 by its C-mannosylation.	Nitrogen	14-15	isthmin 1	Homo sapiens	47-56
33412225-9	2021	Furthermore, ISM1 was N-glycosylated only in these C-mannosylation-defective cells.	Nitrogen	22-23	isthmin 1	Homo sapiens	13-17
33245793-0	2021	miR169c-NFYA-C-ENOD40 modulates nitrogen inhibitory effects in soybean nodulation.	Nitrogen	32-40	MIR169C	Glycine max	0-7
33245793-2	2021	We functionally investigated miR169c-GmNFYA-C-GmENOD40 under multiple N conditions in soybean, and elucidated their regulatory roles in soybean nodulation through analyzing expression pattern, miRNA-mRNA interaction, phenotype of transgenic soybean plants and genetic interactions.	Nitrogen	39-40	MIR169C	Glycine max	29-36
33245793-3	2021	We found that miR169c expression was induced by high N, while its target GmNFYA-C was preferentially expressed in nodules and induced by rhizobium inoculation.	Nitrogen	53-54	MIR169C	Glycine max	14-21
33245793-8	2021	We discover a new regulatory pathway involving the miR169c-NFYA-C-ENOD40 module that regulates soybean nodulation in response to N availability, which provides substantial new insights into the mechanisms underlying the N inhibitory effect on nodulation.	Nitrogen	59-60	MIR169C	Glycine max	51-58
33245793-8	2021	We discover a new regulatory pathway involving the miR169c-NFYA-C-ENOD40 module that regulates soybean nodulation in response to N availability, which provides substantial new insights into the mechanisms underlying the N inhibitory effect on nodulation.	Nitrogen	67-68	MIR169C	Glycine max	51-58
32997967-0	2021	Discarded antibiotic mycelial residues derived nitrogen-doped porous carbon for electrochemical energy storage and simultaneous reduction of antibiotic resistance genes(ARGs).	Nitrogen	47-55	serpin family A member 2 (gene/pseudogene)	Homo sapiens	169-173
33320095-6	2020	This study sheds light on differential specificities and roles of UGGT1 and UGGT2 and provides insight into the cellular reliance on carbohydrate-dependent chaperone system to facilitate proper folding and maturation of the cellular N-glycoproteome.	Nitrogen	233-234	UDP-glucose glycoprotein glucosyltransferase 2	Homo sapiens	76-81
33229537-5	2020	2) Glucocorticoid receptor (GR), an immunity-modulating transcription factor (TF), is up-regulated in 2-KO cells and also physically binds to UBR1, strongly suggesting that GR is a physiological substrate of the Arg/N-degron pathway.	Nitrogen	216-217	ubiquitin protein ligase E3 component n-recognin 1	Homo sapiens	142-146
33337195-1	2020	We articulate confocal microscopy and electron spin resonance to implement spin-to-charge conversion in a small ensemble of nitrogen-vacancy (NV) centers in bulk diamond and demonstrate charge conversion of neighboring defects conditional on the NV spin state.	Nitrogen	124-132	spindlin 1	Homo sapiens	75-79
33337195-1	2020	We articulate confocal microscopy and electron spin resonance to implement spin-to-charge conversion in a small ensemble of nitrogen-vacancy (NV) centers in bulk diamond and demonstrate charge conversion of neighboring defects conditional on the NV spin state.	Nitrogen	124-132	spindlin 1	Homo sapiens	75-79
31458237-7	2018	The high selectivities of MP1 and MP2 were confirmed by experimental column breakthrough experiments with CO2/N2 selectivity values of 23 and 45, respectively.	Nitrogen	110-112	tryptase pseudogene 1	Homo sapiens	34-37
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	autophagy protein ATG9	Saccharomyces cerevisiae S288C	90-94
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	proteinase A	Saccharomyces cerevisiae S288C	183-202
30232842-2	2018	In this study, a metal-organic framework based synthetic route to couple two non-noble-metal-based catalysts, CoP and Mo2 C, supported on nitrogen-doped carbon has been developed.	Nitrogen	138-146	caspase recruitment domain family member 16	Homo sapiens	110-113
33260464-4	2020	While the N-starvation lipophagy strictly depended on the core autophagic machinery (Atg1-Atg9, Atg18, and Vps15), vacuole fusion machinery (Vam7 and Ypt7), and vacuolar proteolysis (proteinases A and B), only Atg6 and proteinases A and B were essential for the S-phase lipophagy.	Nitrogen	10-11	proteinase A	Saccharomyces cerevisiae S288C	219-238
33222666-9	2021	Earlier studies using ELISA as a technique, reveal a correlation between plasma Klotho, eGFR, serum creatine, and Blood Urea Nitrogen (BUN) levels.	Nitrogen	125-133	klotho	Homo sapiens	80-86
33491687-1	2021	A quasi-operando NH3 temperature-programmed reduction method (NH3-TPR), with N2:Cu = 1:1, is developed to quantify total Cu(ii) ions in Cu-SSZ-13 quenched from SCR-relevant reactions, and its accuracy is confirmed by in situ EPR.	Nitrogen	77-79	translocated promoter region, nuclear basket protein	Homo sapiens	66-69
33619857-1	2021	Gut microorganisms metabolize azobenzene compounds (Ph1-N=N-Ph2) into free aniline products (Ph1-NH2 + H2N-Ph2), a process that has been largely investigated to reduce dyes residues in the textile industry.	Nitrogen	56-57	polyhomeotic homolog 2	Homo sapiens	60-63
33619857-1	2021	Gut microorganisms metabolize azobenzene compounds (Ph1-N=N-Ph2) into free aniline products (Ph1-NH2 + H2N-Ph2), a process that has been largely investigated to reduce dyes residues in the textile industry.	Nitrogen	56-57	polyhomeotic homolog 2	Homo sapiens	107-110
33615395-13	2021	In the jejunum, the expression of B0AT1 was similar to that in the duodenum, and the expression of rBAT increased significantly in the 0.30 and 0.45 mg/kg NS-Gly groups (P < 0.05).	Nitrogen	155-157	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	99-103
30232842-3	2018	The strategy enables the formation of a nanohybrid with an attractive pea-like morphology, in which spherical CoP particles ( 10 nm) are embedded on two-dimensional nitrogen-doped carbon enriched with ultrafine Mo2 C nanoparticles.	Nitrogen	165-173	caspase recruitment domain family member 16	Homo sapiens	110-113
32907713-5	2020	While the chl1-5 mutant showed a high NR activity with a high level of auxin in the meristematic zone and a weaker response to nitrogen changes, when compared with the wild-type plants.	Nitrogen	127-135	nitrate transporter 1.1	Arabidopsis thaliana	10-14
30355725-6	2018	We identify conserved N-glycosylated sites and describe the effect of mutating these residues on BMP pathway activity in Drosophila Functional analysis reveals that loss of individual Sog glycosylation sites enhances BMP antagonism and/or increases the spatial range of Sog effects in the tissue.	Nitrogen	22-23	decapentaplegic	Drosophila melanogaster	217-220
33104355-3	2020	The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination.	Nitrogen	93-94	synemin	Homo sapiens	68-71
33104355-3	2020	The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination.	Nitrogen	131-132	synemin	Homo sapiens	68-71
33580824-2	2021	PMM2 encodes phosphomannomutase 2, a key enzyme in N-glycosylation.	Nitrogen	51-52	phosphomannomutase 2	Homo sapiens	0-4
33580824-2	2021	PMM2 encodes phosphomannomutase 2, a key enzyme in N-glycosylation.	Nitrogen	51-52	phosphomannomutase 2	Homo sapiens	13-33
33580824-3	2021	While biallelic coding PMM2 mutations are involved in congenital disorder of glycosylation CDG1A, that particular variant in the promoter of the gene, either in the homozygous state or associated with a mutation in the coding exons of the gene, is thought to restrict the N-glycosylation defect to the kidney and the pancreas.	Nitrogen	272-273	phosphomannomutase 2	Homo sapiens	23-27
33614704-8	2020	The straightening of TM5 modifies the structure of the P-N linker that sits above it, and which comprises the 351DKTG354 conserved motif, resulting in an increase of the distance between ATP and the phosphorylation site.	Nitrogen	57-58	tropomyosin 3	Homo sapiens	21-24
33216607-0	2020	Orbital and Spin Dynamics of Single Neutrally-Charged Nitrogen-Vacancy Centers in Diamond.	Nitrogen	54-62	spindlin 1	Homo sapiens	12-16
30524295-3	2018	Results show that SGK1 inhibitor EMD638683 significantly reversed renal dysfunction and cardiac dysfunction in echocardiography as indicated by decreased blood urine nitrogen and serum creatinine in AngII-infused mice.	Nitrogen	166-174	serum/glucocorticoid regulated kinase 1	Mus musculus	18-22
32717518-5	2020	Moreover, the ratio of chemical oxygen demand to total nitrogen (C/N) was identified as an effective regulator for the distribution of C14-HSL and 3-oxo-C14-HSL.	Nitrogen	55-63	lipase E, hormone sensitive type	Homo sapiens	139-142
32717518-5	2020	Moreover, the ratio of chemical oxygen demand to total nitrogen (C/N) was identified as an effective regulator for the distribution of C14-HSL and 3-oxo-C14-HSL.	Nitrogen	67-68	lipase E, hormone sensitive type	Homo sapiens	139-142
32952646-9	2020	The concentrations of CD68 and TGF-beta1 in the study group positively correlated with the renal injury indexes, such as blood urea nitrogen (BUN), serum creatinine (SCR), uric acid (UA) and the 24-h urinary protein quantity (P<0.05).	Nitrogen	132-140	CD68 molecule	Homo sapiens	22-26
33513769-4	2021	N2 adsorption analysis and FT-IR spectroscopy were used to assess the successful grafting of ICOS-Fc on the surface of Sr-containing MBGs, which were also proved to retain the peculiar ability to release osteogenic strontium ions and an excellent bioactivity after functionalization.	Nitrogen	0-2	inducible T cell costimulator	Homo sapiens	93-97
33483465-2	2021	In this work, we studied GRP94 in M1/LPS + IFNgamma and M2/IL-4 primary macrophages derived from human monocytes (isolated from buffy coats), in basal and ER stress conditions induced by thapsigargin (Tg), an inducer of ER calcium depletion and tunicamycin (Tm), an inhibitor of N-glycosylation.	Nitrogen	45-46	heat shock protein 90 beta family member 1	Homo sapiens	25-30
33523898-0	2021	The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress.	Nitrogen	78-79	TRAP	Homo sapiens	4-33
32996649-0	2020	N-glycosylation of CREBH improves lipid metabolism and attenuates lipotoxicity in NAFLD by modulating PPARalpha and SCD-1.	Nitrogen	0-1	cAMP responsive element binding protein 3-like 3	Mus musculus	19-24
31544888-3	2018	In the CFPS step, we employed our original techniques: (1) "Zipbody" as a modified Fab (fragment of antigen binding) format, in which the active Fab formation is facilitated by adhesive leucine zipper peptides fused at the C-termini of the light and heavy chains; and (2) an N-terminal SKIK peptide tag that can markedly increase protein production.	Nitrogen	275-276	FA complementation group B	Homo sapiens	83-86
32996649-0	2020	N-glycosylation of CREBH improves lipid metabolism and attenuates lipotoxicity in NAFLD by modulating PPARalpha and SCD-1.	Nitrogen	0-1	stearoyl-Coenzyme A desaturase 1	Mus musculus	116-121
32666865-2	2020	N-linked glycosylation, by modifying protein functions, may provide an important environmental link predicting vulnerability.Our goals were (1) to find alterations in plasma N-glycome predicting stress-vulnerability; (2) to investigate how trauma affects N-glycome in the plasma (PGP) and in three PTSD-related brain regions (prefrontal cortex, hippocampus and amygdala; BGP), hence uncover specific targets for PTSD treatment.	Nitrogen	0-1	CEA cell adhesion molecule 1	Rattus norvegicus	371-374
33466728-7	2021	Our functional analyses indicate that the N-glycosylated N-terminus and the death domain-containing C-terminus regions are necessary for both the inhibition of Wnt signaling and apoptosis.	Nitrogen	42-43	wingless-type MMTV integration site family, member 8a	Danio rerio	160-163
31544888-3	2018	In the CFPS step, we employed our original techniques: (1) "Zipbody" as a modified Fab (fragment of antigen binding) format, in which the active Fab formation is facilitated by adhesive leucine zipper peptides fused at the C-termini of the light and heavy chains; and (2) an N-terminal SKIK peptide tag that can markedly increase protein production.	Nitrogen	275-276	FA complementation group B	Homo sapiens	145-148
33436543-4	2021	Overexpression of exogenous MMP-10 ameliorated AKI, manifested by decreased serum creatinine, blood urea nitrogen, tubular injury and apoptosis, and increased tubular regeneration.	Nitrogen	105-113	matrix metallopeptidase 10	Homo sapiens	28-34
30320326-2	2018	Due to the Lewis basic nature of well-defined nitrogen sites in triazine units of CTF-1, highly dispersed and size-controlled CdS NPs were obtained and stabilized on the surface of CTF-1 layers.	Nitrogen	46-54	cardiotrophin 1	Homo sapiens	82-87
32878894-5	2020	Furthermore, analysis of various N-linked glycosylation site and cysteine mutants in gp85 revealed that glycosylation sites (N6 and N11) and cysteines (C3 and C9) were directly involved in receptor-gp85 binding and important for the entry of ALV-J into cells.	Nitrogen	33-34	complement C3	Homo sapiens	152-161
32847853-8	2020	We found that EBV gH/gL-N69L/S71V had higher binding affinity for EphA2, indicating that the EBV gL N-glycosylation site might be responsible for inhibiting the binding of gH/gL to EphA2.	Nitrogen	24-25	EPH receptor A2	Homo sapiens	66-71
30320326-2	2018	Due to the Lewis basic nature of well-defined nitrogen sites in triazine units of CTF-1, highly dispersed and size-controlled CdS NPs were obtained and stabilized on the surface of CTF-1 layers.	Nitrogen	46-54	CDP-diacylglycerol synthase 1	Homo sapiens	126-129
32847853-8	2020	We found that EBV gH/gL-N69L/S71V had higher binding affinity for EphA2, indicating that the EBV gL N-glycosylation site might be responsible for inhibiting the binding of gH/gL to EphA2.	Nitrogen	24-25	EPH receptor A2	Homo sapiens	181-186
32847853-9	2020	Loss of N-glycosylation at this site may remove steric hindrance that reduces EBV gH/gL binding to EphA2.	Nitrogen	8-9	EPH receptor A2	Homo sapiens	99-104
33488657-0	2020	ACCELERATED CELL DEATH 6 Acts on Natural Leaf Senescence and Nitrogen Fluxes in Arabidopsis.	Nitrogen	61-69	ankyrin repeat family protein	Arabidopsis thaliana	0-24
33488657-6	2020	Using two near-isogeneic lines, differing solely around the ACD6 locus, we showed that ACD6 regulates rosette growth, leaf chlorophyll content, as well as leaf nitrogen and carbon percentages.	Nitrogen	160-168	ankyrin repeat family protein	Arabidopsis thaliana	87-91
33488657-9	2020	Measurement of N uptake at vegetative and reproductive stages revealed that ACD6 did not modify N uptake efficiency but enhanced nitrogen translocation from root to silique.	Nitrogen	15-16	ankyrin repeat family protein	Arabidopsis thaliana	76-80
30320326-2	2018	Due to the Lewis basic nature of well-defined nitrogen sites in triazine units of CTF-1, highly dispersed and size-controlled CdS NPs were obtained and stabilized on the surface of CTF-1 layers.	Nitrogen	46-54	cardiotrophin 1	Homo sapiens	181-186
33488657-9	2020	Measurement of N uptake at vegetative and reproductive stages revealed that ACD6 did not modify N uptake efficiency but enhanced nitrogen translocation from root to silique.	Nitrogen	129-137	ankyrin repeat family protein	Arabidopsis thaliana	76-80
33488657-10	2020	In this study, we have evidenced a new role of ACD6 in regulating both sequential and monocarpic senescences and disrupting the balance between N remobilization and N uptake that is required for a good seed filling.	Nitrogen	144-145	ankyrin repeat family protein	Arabidopsis thaliana	47-51
33488657-10	2020	In this study, we have evidenced a new role of ACD6 in regulating both sequential and monocarpic senescences and disrupting the balance between N remobilization and N uptake that is required for a good seed filling.	Nitrogen	165-166	ankyrin repeat family protein	Arabidopsis thaliana	47-51
33443146-1	2021	The Ligand of Ate1 (Liat1) is a protein of unknown function that was originally discovered through its interaction with arginyl-tRNA protein transferase 1 (Ate1), a component of the Arg/N-degron pathway of protein degradation.	Nitrogen	130-131	RIKEN cDNA 1700016K19 gene	Mus musculus	20-25
33515429-6	2021	Inducible nitric oxide synthase (iNOS/NOS-II) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2), the major mediators of reactive nitrogen/oxygen species (RNS/ROS) production in the brain, are also upregulated along with the pro-inflammatory cytokines following neurological insult and contribute to disease progression.	Nitrogen	152-160	cytochrome b-245 beta chain	Homo sapiens	50-111
32445493-5	2020	Screening the collection of 374 N-glycomimetics against the plant lectin WFA and the 2 human immune lectins MGL ECD and Langerin ECD produced a number of high affinity binders as lead structures for more selective lectin targeting probes.	Nitrogen	32-33	C-type lectin domain containing 10A	Homo sapiens	108-111
32767150-8	2020	We found that N- and O-glycosylation patterns of CGB7 and CGB3/5/8 are quite similar.	Nitrogen	14-15	chorionic gonadotropin subunit beta 3	Homo sapiens	58-66
33162804-5	2020	First, we found that the absence of Klotho aggravated diabetic phenotypes indicated by podocyte injury accompanied by elevated urea albumin creatinine ratio (UACR), creatinine and urea nitrogen.	Nitrogen	185-193	klotho	Homo sapiens	36-42
32892942-8	2020	Moreover, in the LC-MS/MS analysis of real biological sample, a total of 344 unique N-glycosites in 598 unique N-glycopeptides from 172 N-glycoproteins were identified from 2 muL human serum after deglycosylated by PNGase F, and 825 intact N-glycopeptides with different types of glycoform were detected when directly analyzed the N-glycopeptides enriched by PAM-OH HMS.	Nitrogen	84-85	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	359-362
33515429-6	2021	Inducible nitric oxide synthase (iNOS/NOS-II) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2), the major mediators of reactive nitrogen/oxygen species (RNS/ROS) production in the brain, are also upregulated along with the pro-inflammatory cytokines following neurological insult and contribute to disease progression.	Nitrogen	152-160	cytochrome b-245 beta chain	Homo sapiens	113-117
30374089-0	2018	Arabidopsis NITROGEN LIMITATION ADAPTATION regulates ORE1 homeostasis during senescence induced by nitrogen deficiency.	Nitrogen	99-107	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	12-42
30374089-3	2018	Here, we show that nla and pho2 (also known as ubc24) plants develop rapid leaf senescence under nitrogen-starvation condition, whereas ore1 and nla/ore1 and pho2 (ubc24)/ore1 plants stay green.	Nitrogen	97-105	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	19-22
33255057-0	2021	Fe3+ and intracellular pH determination based on orange fluorescence carbon dots co-doped with boron, nitrogen and sulfur.	Nitrogen	102-110	l(2)FE3	Drosophila melanogaster	0-3
32932820-8	2020	In P. vulgaris, we confirmed that N-starvation stimulated nodulation by regulating expression of PvNLP2, closely related to AtNLP6 and AtNLP7 with another common origin (OG0004041).	Nitrogen	34-35	NIN like protein 7	Arabidopsis thaliana	135-141
29958959-13	2018	In vivo, LEP treatment significantly reduced the effects of CCl4 intoxication on serum liver biomarkers (AST, ALT, LDH, and GGT) and the effect of cisplatin on serum renal biomarkers (urea, blood urea nitrogen, creatinine, and uric acid).	Nitrogen	201-209	leptin	Mus musculus	9-12
32474175-9	2020	The high n-3 PUFA diet also increased the mRNA expressions of BDNF, TrKB and CREB, as well as the protein concentration of pCREB as gestation progressed, compared to the other groups.	Nitrogen	9-10	neurotrophic tyrosine kinase, receptor, type 2	Mus musculus	68-72
33374407-3	2020	Here, we combined the PASylation technology with enzymatic in situ N-acetylation by RimJ to produce a long-acting version of Talpha1 in Escherichia coli at high yield.	Nitrogen	67-68	trace amine associated receptor 1	Homo sapiens	125-132
33339104-2	2020	In the last decade, different studies have proven that reactive oxygen species (ROS) and reactive nitrogen species (RNS) are involved in the development and maintenance of inflammatory pain and hyperalgesia via the post-translation modification of key proteins, such as manganese superoxide dismutase (MnSOD).	Nitrogen	98-106	superoxide dismutase 2	Rattus norvegicus	270-300
32175446-6	2018	The proportions of conjugated linoleic acid (CLA), n-6 PUFA, n-3 PUFA, and essential FA (linoleic and alpha -linolenic) were also significantly higher in P lambs (2.10, 8.50, 4.55, and 8.80 g 100 g  - 1   FAME, respectively) than in S lambs (0.65, 3.27, 1.50, and 3.64 g 100 g  - 1   FAME, respectively).	Nitrogen	13-14	PUFA	Ovis aries	55-59
33049851-2	2020	Results demonstrated that N-glycosylation deficient Arabidopsis mutants (stt3a and ManI) were more susceptible against Pseudomonas syringae pv.	Nitrogen	26-27	staurosporin and temperature sensitive 3-like A	Arabidopsis thaliana	73-78
32175446-6	2018	The proportions of conjugated linoleic acid (CLA), n-6 PUFA, n-3 PUFA, and essential FA (linoleic and alpha -linolenic) were also significantly higher in P lambs (2.10, 8.50, 4.55, and 8.80 g 100 g  - 1   FAME, respectively) than in S lambs (0.65, 3.27, 1.50, and 3.64 g 100 g  - 1   FAME, respectively).	Nitrogen	13-14	PUFA	Ovis aries	65-69
30040982-3	2018	Both GFRA1 and RET are membrane proteins which are N-glycosylated but no O-linked sialylation site on GFRA1 or RET has been reported.	Nitrogen	51-52	ret proto-oncogene	Homo sapiens	15-18
33322583-10	2020	The better performance of the CNT doped with nitrogen was confirmed with CNT@2%Fe_N_MB, and the magnetic character facilitated its recovery after treatment, and did not affect its good catalytic properties.	Nitrogen	45-53	solute carrier family 28 member 2	Homo sapiens	73-78
30130540-11	2018	In vivo experiments showed that HOTAIR negatively modulated miR-22 and positively modulated HMGB1 and that HOTAIR knockdown decreased renal function indicators (blood urea nitrogen [BUN] and serum creatinine).	Nitrogen	172-180	HOX transcript antisense RNA	Homo sapiens	107-113
33297922-12	2021	Dysregulated levels of these genes are linked to molecular processes like cellular senescence, hypoxia, glutathione synthesis, amino acid modification, increased nitrogen content, synthesis of BCAAs, cholesterol biosynthesis, steroid hormone signalling and VEGF pathway.	Nitrogen	162-170	vascular endothelial growth factor A	Mus musculus	257-261
30120198-1	2018	Nodulation outer protein M (NopM) is an IpaH family type three (T3) effector secreted by the nitrogen-fixing nodule bacterium Sinorhizobium sp.	Nitrogen	93-101	E3 ubiquitin--protein ligase	Sinorhizobium fredii NGR234	28-32
33273096-5	2020	miR-223 restricts the EHT of lymphoid-myeloid lineages by suppressing the mannosyltransferase alg2 and sialyltransferase st3gal2, two enzymes involved in protein N-glycosylation.	Nitrogen	162-163	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	94-98
30221265-5	2018	Importantly, our calculations show that the ETM/perovskite interface interaction is enhanced after the introduction of the nitrogen atom and amino group thanks to the added NPb interaction, which favors electron transport with the newly designed ETMs.	Nitrogen	123-131	neuropeptide B	Homo sapiens	173-176
33038666-5	2020	The results revealed that O-methylation at C-7, together with the introduction of nitrogen atoms and aromatic moieties at C-4 or C-4", significantly improved the activity, being compounds 27 and 37 the strongest P-gp modulators and much more active than verapamil.	Nitrogen	82-90	phosphoglycolate phosphatase	Mus musculus	212-216
32967780-1	2020	Polymorphic human and cynomolgus macaque flavin-containing monooxygenases (FMO) 3 are important oxygenation enzymes for nitrogen-containing drugs.	Nitrogen	120-128	dimethylaniline monooxygenase [N-oxide-forming] 3	Macaca fascicularis	41-81
30345292-7	2018	The accumulation of N-Hcy in hair keratin led to a progressive reduction of N-Hcy-keratin solubility in sodium dodecyl sulfate, from 0.39 +- 0.04 in wild-type mice to 0.19 +- 0.03, 0.14 +- 0.01, and 0.07 +- 0.03 in Mthfr -/-, Cse -/-, or Cbs -/-animals, respectively.	Nitrogen	20-21	cystathionine beta-synthase	Mus musculus	238-241
32734505-9	2020	After adjusting for gender and age, serum CTRP12 level was negatively correlated with the duration of diabetes, blood urea nitrogen (BUN), uric acid (UA) and 24-h urinary albumin excretion rate (UAE) in T2DM patients.	Nitrogen	123-131	C1q and TNF related 12	Homo sapiens	42-48
30137992-1	2018	The reaction of the OH radical with isoprene, C5H8 (R1), has been studied over the temperature range 298-794 K and bath gas pressures of nitrogen from 50 to 1670 Torr using laser flash photolysis (LFP) to generate OH and laser-induced fluorescence (LIF) to observe OH removal.	Nitrogen	137-145	CD1b molecule	Homo sapiens	46-54
32827664-0	2020	Dietary long-chain n-3 PUFA mitigate CD4+ T cell/adipocyte inflammatory interactions in co-culture models of obese adipose tissue.	Nitrogen	10-11	CD4 antigen	Mus musculus	37-40
30048775-7	2018	Moreover, an Arabidopsis grf6 T-DNA insertion mutant was found to have a nitrogen stress-sensitive phenotype.	Nitrogen	73-81	G-box regulating factor 6	Arabidopsis thaliana	25-29
33037147-8	2020	A significant increase in the overall ATG4 proteolytic activity in Arabidopsis was detected under nitrogen starvation and osmotic stress and can be inhibited by sulfide.	Nitrogen	98-106	UbiA prenyltransferase family protein	Arabidopsis thaliana	38-42
33048402-0	2020	NITROGEN RESPONSE DEFICIENCY 1 - mediated CHL1 induction contributes to optimized growth performance during altered nitrate availability in Arabidopsis.	Nitrogen	0-8	nitrate transporter 1.1	Arabidopsis thaliana	42-46
30048775-8	2018	GRF6 is a 14-3-3 protein with elevated abundance upon nitrogen starvation and it may function as a positive regulator during nitrogen stress adaptation.	Nitrogen	54-62	G-box regulating factor 6	Arabidopsis thaliana	0-4
30048775-8	2018	GRF6 is a 14-3-3 protein with elevated abundance upon nitrogen starvation and it may function as a positive regulator during nitrogen stress adaptation.	Nitrogen	125-133	G-box regulating factor 6	Arabidopsis thaliana	0-4
33248586-8	2020	Apparent metabolizable energy corrected for nitrogen (AMEn) was determined in EXP 2.	Nitrogen	44-52	expansin	Glycine max	78-83
30205487-0	2018	Preparation of Highly Catalytic N-Doped Carbon Dots and Their Application in SERS Sulfate Sensing.	Nitrogen	32-33	seryl-tRNA synthetase 2, mitochondrial	Homo sapiens	77-81
29782851-3	2018	Cbln1, 2 and 4 harbor two N-linked glycosylation sites, one at the N-terminus is in a region implicated in Nrxn binding and the second is in the C1q domain, a region involved in Grid2 binding.	Nitrogen	26-27	cerebellin 1 precursor protein	Mus musculus	0-14
33108721-5	2020	We show the dangling-bond-free vdW interface can allow an impressive average spin injection efficiency of 78% to produce persistent valley polarization in monolayer MoS2 (WSe2) over 10% from liquid-nitrogen temperature to above 200 K. We attribute the valley polarization of monolayer MoS2 (WSe2) to selective spin injection from chiral 2D perovskites, which can effectively introduce population imbalance between valleys in monolayer MoS2 (WSe2).	Nitrogen	198-206	spindlin 1	Homo sapiens	77-81
33184334-7	2020	A total nitrogen instrument (TNM-1) was used to study the urea release from single- and double-layered hollow nanofibres yarn in water.	Nitrogen	8-16	teneurin transmembrane protein 1	Homo sapiens	29-34
30067352-4	2018	The developed approach to Rh2 nitrenoids, based on photochemical cleavage of N-Cl bonds in N-chloroamido ligands, has enabled characterization of a reactive Rh2 nitrenoid by mass spectrometry and transient absorption spectroscopy.	Nitrogen	77-78	Rh associated glycoprotein	Homo sapiens	26-29
33169178-6	2020	Two new characteristic features appear: (1) paramagnetic substitutional nitrogen (P1 centres with spin 1/2) with an electron paramagnetic resonance characteristic triplet hyperfine structure due to the I = 1 magnetic moment of the nitrogen nuclear spin and (2) the green spectral photoluminescence signature of the nitrogen-vacancy-nitrogen centres.	Nitrogen	72-80	spindlin 1	Homo sapiens	98-106
33169178-6	2020	Two new characteristic features appear: (1) paramagnetic substitutional nitrogen (P1 centres with spin 1/2) with an electron paramagnetic resonance characteristic triplet hyperfine structure due to the I = 1 magnetic moment of the nitrogen nuclear spin and (2) the green spectral photoluminescence signature of the nitrogen-vacancy-nitrogen centres.	Nitrogen	231-239	spindlin 1	Homo sapiens	98-106
33169178-6	2020	Two new characteristic features appear: (1) paramagnetic substitutional nitrogen (P1 centres with spin 1/2) with an electron paramagnetic resonance characteristic triplet hyperfine structure due to the I = 1 magnetic moment of the nitrogen nuclear spin and (2) the green spectral photoluminescence signature of the nitrogen-vacancy-nitrogen centres.	Nitrogen	231-239	spindlin 1	Homo sapiens	98-106
33169178-6	2020	Two new characteristic features appear: (1) paramagnetic substitutional nitrogen (P1 centres with spin 1/2) with an electron paramagnetic resonance characteristic triplet hyperfine structure due to the I = 1 magnetic moment of the nitrogen nuclear spin and (2) the green spectral photoluminescence signature of the nitrogen-vacancy-nitrogen centres.	Nitrogen	231-239	spindlin 1	Homo sapiens	98-106
30067352-4	2018	The developed approach to Rh2 nitrenoids, based on photochemical cleavage of N-Cl bonds in N-chloroamido ligands, has enabled characterization of a reactive Rh2 nitrenoid by mass spectrometry and transient absorption spectroscopy.	Nitrogen	77-78	Rh associated glycoprotein	Homo sapiens	157-160
30046793-0	2018	CdS p-n heterojunction co-boosting with Co3O4 and Ni-MOF-74 for photocatalytic hydrogen evolution.	Nitrogen	6-7	CDP-diacylglycerol synthase 1	Homo sapiens	0-3
32424239-6	2020	Moreover, pretreatment of rats with recombinant human MG53 protein (rhMG53, 2 mg/mL) alleviated iopromide-induced injury in the kidney, which was determined by measuring serum creatinine, blood urea nitrogen and renal histological changes.	Nitrogen	199-207	tripartite motif containing 72	Homo sapiens	54-58
32996649-8	2020	The expression of NAFLD-related factors was detected to further verify the role of N-linked glycosylation of CREBH in lipid and sterol metabolism, inflammation, and lipotoxicity.	Nitrogen	18-19	cAMP responsive element binding protein 3-like 3	Mus musculus	109-114
30110893-0	2018	Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization.	Nitrogen	15-16	interferon alpha inducible protein 27	Homo sapiens	66-69
33119615-3	2020	Our previous in silico study indicated a higher binding affinity for mutated G82S RAGE, which could be caused due to changes in N linked glycosylation at residue N81.	Nitrogen	128-129	advanced glycosylation end-product specific receptor	Homo sapiens	82-86
30103455-0	2018	Nitrogen Supply and Leaf Age Affect the Expression of TaGS1 or TaGS2 Driven by a Constitutive Promoter in Transgenic Tobacco.	Nitrogen	0-8	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	63-68
30103455-3	2018	Four independent transformed lines, GS1-TR1, GS1-TR2, GS2-TR1 and GS2-TR2, were used for the nitrogen treatment.	Nitrogen	93-101	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	54-57
33105790-5	2020	In contrast, both 2Cn(Spacer) NTf2 with nitrogen-containing spacers and nonionic surfactants remained adsorbed at the interface at high concentrations.	Nitrogen	40-48	nuclear transport factor 2	Homo sapiens	30-34
33205023-1	2020	HIV-1 envelope (Env) N-glycosylation impact virus-cell entry and immune evasion.	Nitrogen	21-22	endogenous retrovirus group K member 20	Homo sapiens	16-19
33205023-3	2020	Here, analysis of two Env variants from the same donor, with differing functional characteristics and N-glycosylation-site composition, revealed that changes to key N-glycosylation sites affected the Env structure at distant locations and had a ripple effect on Env-wide glycan processing, virus infectivity, antibody recognition, and virus neutralization.	Nitrogen	102-103	endogenous retrovirus group K member 20	Homo sapiens	22-25
33205023-3	2020	Here, analysis of two Env variants from the same donor, with differing functional characteristics and N-glycosylation-site composition, revealed that changes to key N-glycosylation sites affected the Env structure at distant locations and had a ripple effect on Env-wide glycan processing, virus infectivity, antibody recognition, and virus neutralization.	Nitrogen	102-103	endogenous retrovirus group K member 20	Homo sapiens	200-203
33205023-3	2020	Here, analysis of two Env variants from the same donor, with differing functional characteristics and N-glycosylation-site composition, revealed that changes to key N-glycosylation sites affected the Env structure at distant locations and had a ripple effect on Env-wide glycan processing, virus infectivity, antibody recognition, and virus neutralization.	Nitrogen	102-103	endogenous retrovirus group K member 20	Homo sapiens	200-203
33205023-3	2020	Here, analysis of two Env variants from the same donor, with differing functional characteristics and N-glycosylation-site composition, revealed that changes to key N-glycosylation sites affected the Env structure at distant locations and had a ripple effect on Env-wide glycan processing, virus infectivity, antibody recognition, and virus neutralization.	Nitrogen	165-166	endogenous retrovirus group K member 20	Homo sapiens	22-25
33205023-3	2020	Here, analysis of two Env variants from the same donor, with differing functional characteristics and N-glycosylation-site composition, revealed that changes to key N-glycosylation sites affected the Env structure at distant locations and had a ripple effect on Env-wide glycan processing, virus infectivity, antibody recognition, and virus neutralization.	Nitrogen	165-166	endogenous retrovirus group K member 20	Homo sapiens	200-203
33205023-3	2020	Here, analysis of two Env variants from the same donor, with differing functional characteristics and N-glycosylation-site composition, revealed that changes to key N-glycosylation sites affected the Env structure at distant locations and had a ripple effect on Env-wide glycan processing, virus infectivity, antibody recognition, and virus neutralization.	Nitrogen	165-166	endogenous retrovirus group K member 20	Homo sapiens	200-203
32544241-8	2020	Therefore, our results suggest that protein N-terminal acetylation catalyzed by Naa50 plays an essential role in Arabidopsis growth and osmotic stress responses.	Nitrogen	44-45	peptide alpha-N-acetyltransferase subunit NAT5	Saccharomyces cerevisiae S288C	80-85
32982674-7	2020	Surprisingly, we found that nNOS knockdown exhibited greatly reduced excitatory synaptic transmission concomitant with the lower surface expression of GluN2B-containing N-methyl-D-aspartate receptors and postsynaptic density protein 95 in mice.	Nitrogen	29-30	discs large MAGUK scaffold protein 4	Mus musculus	204-235
30103455-3	2018	Four independent transformed lines, GS1-TR1, GS1-TR2, GS2-TR1 and GS2-TR2, were used for the nitrogen treatment.	Nitrogen	93-101	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	66-69
30103455-4	2018	Under nitrogen-sufficient conditions, the leaves of GS2-TR showed high accumulation of the TaGS2 transcript, while those of GS1-TR showed a low TaGS1 transcript levels.	Nitrogen	6-14	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	52-55
32922663-0	2020	Urinary glycoproteomic profiling of non-muscle invasive and muscle invasive bladder carcinoma patients reveals distinct N-glycosylation pattern of CD44, MGAM, and GINM1.	Nitrogen	120-121	glycosylated integral membrane protein 1	Homo sapiens	163-168
30103455-4	2018	Under nitrogen-sufficient conditions, the leaves of GS2-TR showed high accumulation of the TaGS2 transcript, while those of GS1-TR showed a low TaGS1 transcript levels.	Nitrogen	6-14	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	91-96
32922663-9	2020	Further, we identified distinct N-glycosylation pattern of CD44, MGAM, and GINM1 between NMIBC and MIBC patients, which may be associated with disease progression in bladder cancer.	Nitrogen	32-33	glycosylated integral membrane protein 1	Homo sapiens	75-80
30103455-6	2018	In addition, the TaGS1 and TaGS2 transcript levels were highest in the middle leaves under nitrogen-sufficient and starvation conditions.	Nitrogen	91-99	glutamine synthetase leaf isozyme, chloroplastic	Triticum aestivum	27-32
33312062-9	2020	Serum TNC was significantly correlated with the pulse, serum CK-T, CK-MB, high-density lipoprotein-cholesterol, and blood urea nitro GEN.	Nitrogen	127-136	tenascin C	Homo sapiens	6-9
29759226-1	2018	Luminol-nitrogen doped graphene quantum dot (luminol-NGQDs) nanocomposite was synthesized and a novel electrochemiluminescence resonance energy transfer (ECL-RET) process occurred between luminol as the donor and NGQDs as the acceptor in the composite.	Nitrogen	8-16	ret proto-oncogene	Homo sapiens	158-161
32569873-4	2020	In contrast, nitrogen-containing BPs potently inhibit FPP synthase, an enzyme of the mevalonate (cholesterol biosynthesis) pathway.	Nitrogen	13-21	farnesyl diphosphate synthase	Homo sapiens	54-66
33204593-2	2020	The most common CDG is caused by pathogenic variants in the phosphomannomutase 2 gene (PMM2), which impairs one of the first steps of N-glycosylation and affects multiple organ systems.	Nitrogen	134-135	phosphomannomutase 2	Homo sapiens	60-80
33204593-2	2020	The most common CDG is caused by pathogenic variants in the phosphomannomutase 2 gene (PMM2), which impairs one of the first steps of N-glycosylation and affects multiple organ systems.	Nitrogen	134-135	phosphomannomutase 2	Homo sapiens	87-91
29939738-1	2018	The reaction of methanol (CH3OH) with atomic nitrogen was studied considering three elementary reactions, the hydrogen abstractions from the hydroxyl or methyl groups (R1 and R3, respectively) and the C-O bond break (R2).	Nitrogen	45-53	CD1b molecule	Homo sapiens	168-177
32776922-7	2020	We further show that this arginine export involves Ypq2, a vacuolar protein homologous to the human lysosomal cationic amino acid exporter PQLC2 and whose activity is detected only in nitrogen-starved cells.	Nitrogen	184-192	solute carrier family 66 member 1	Homo sapiens	139-144
32719549-7	2020	Furtherly, G6PD knockdown activated the JNK pathway, which then blocked the AKT/GSK-3beta/Snail axis to induce E-Cadherin expression and transcriptionally regulated MGAT3 expression to promote bisecting GlcNAc-branched N-glycosylation of E-Cadherin.	Nitrogen	41-42	glucose-6-phosphate dehydrogenase	Homo sapiens	11-15
32719549-9	2020	CONCLUSIONS: Suppression of G6PD promoted the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin via activating the JNK pathway, which thus acted on OSCC metastasis.	Nitrogen	2-3	glucose-6-phosphate dehydrogenase	Homo sapiens	28-32
29457375-0	2018	Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjogren"s Syndrome.	Nitrogen	85-86	FA complementation group B	Homo sapiens	70-73
32659346-2	2020	Studies from our laboratory show that the intrinsic pathway proapoptotic proteins BAX and caspase-3 (CASP3) lie upstream of mitochondrial production of oxidative stress-inducing reactive species (RS) such as reactive oxygen and reactive nitrogen species (ROS and RNS) in apoptotic and nonapoptotic neurons in cell culture.	Nitrogen	237-245	BCL2-associated X protein	Mus musculus	82-85
32659346-2	2020	Studies from our laboratory show that the intrinsic pathway proapoptotic proteins BAX and caspase-3 (CASP3) lie upstream of mitochondrial production of oxidative stress-inducing reactive species (RS) such as reactive oxygen and reactive nitrogen species (ROS and RNS) in apoptotic and nonapoptotic neurons in cell culture.	Nitrogen	237-245	caspase 3	Mus musculus	90-99
32659346-2	2020	Studies from our laboratory show that the intrinsic pathway proapoptotic proteins BAX and caspase-3 (CASP3) lie upstream of mitochondrial production of oxidative stress-inducing reactive species (RS) such as reactive oxygen and reactive nitrogen species (ROS and RNS) in apoptotic and nonapoptotic neurons in cell culture.	Nitrogen	237-245	caspase 3	Mus musculus	101-106
33019636-0	2020	Nitrite Reductase 1 Is a Target of Nitric Oxide-Mediated Post-Translational Modifications and Controls Nitrogen Flux and Growth in Arabidopsis.	Nitrogen	103-111	nitrite reductase 1	Arabidopsis thaliana	0-19
33019636-4	2020	NiR1 seems to be a key target in regulating nitrogen assimilation and NO homeostasis, being relevant to the control of both plant growth and performance under stress conditions.	Nitrogen	44-52	nitrite reductase 1	Arabidopsis thaliana	0-4
32823246-6	2020	Additionally, the activity of fructokinase and hexokinase, which are involved in hexose phosphorylation, and transcript levels of MdFRK2 and MdHK3 were significantly upregulated under nitrogen deficiency, and the hexose phosphate products F6P and G6P accumulated greatly in the roots.	Nitrogen	184-192	probable fructokinase-4	Malus domestica	30-42
32687329-3	2020	Additionally, we have developed the first known synthesis of a symmetrical tripodal NP3 ligand N(CH2CH2PiBu2)3 using bench safe ammonium acetate as the lone nitrogen source (7).	Nitrogen	157-165	leukemia NUP98 fusion partner 1	Homo sapiens	84-87
32687329-4	2020	This new protocol eliminates the use of extremely dangerous nitrogen mustard reagents typically required to synthesize NP3 ligands.	Nitrogen	60-68	leukemia NUP98 fusion partner 1	Homo sapiens	119-122
32756045-4	2020	The detonation velocity (D) and detonation pressure (P) of BATZM Cl2 were estimated using the nitrogen equivalent equation according to the experimental density; BATZM Cl2 has a higher detonation velocity (7143.60 +- 3.66 m s-1) and detonation pressure (21.49 +- 0.03 GPa) than TNT.	Nitrogen	94-102	endogenous retrovirus group W member 5	Homo sapiens	65-68
32756045-4	2020	The detonation velocity (D) and detonation pressure (P) of BATZM Cl2 were estimated using the nitrogen equivalent equation according to the experimental density; BATZM Cl2 has a higher detonation velocity (7143.60 +- 3.66 m s-1) and detonation pressure (21.49 +- 0.03 GPa) than TNT.	Nitrogen	94-102	endogenous retrovirus group W member 5	Homo sapiens	168-171
32513868-6	2020	On the basis of screening for 20 soluble proteins that may be N-glycosylated in the ER in the ste24  strain, we identified the transcription factor Rme1 as a protein that is partially N-glycosylated despite the lack of a signal peptide.	Nitrogen	62-63	zinc metalloprotease	Saccharomyces cerevisiae S288C	94-99
32513868-6	2020	On the basis of screening for 20 soluble proteins that may be N-glycosylated in the ER in the ste24  strain, we identified the transcription factor Rme1 as a protein that is partially N-glycosylated despite the lack of a signal peptide.	Nitrogen	184-185	zinc metalloprotease	Saccharomyces cerevisiae S288C	94-99
32708238-7	2020	The Tonset (initial degradation temperature) and Tmax (maximum degradation temperature) after adding 5.0 wt % CNF was increased by 20  C, and 10  C, respectively in the nitrogen atmosphere.	Nitrogen	169-177	NPHS1 adhesion molecule, nephrin	Homo sapiens	110-113
29573412-9	2018	Fed-batch fermentation of the tHMG1 and DGA1 co-overexpressing yeast strain resulted in the production of squalene at a titer of 445.6 mg/L in a nitrogen-limited minimal medium.	Nitrogen	145-153	diacylglycerol O-acyltransferase	Saccharomyces cerevisiae S288C	40-44
32574492-3	2020	The mechanism of this promising transformation was unveiled by means of experiments together with density functional theory (DFT) calculations, which inspired Milstein and co-workers to use similar (PNN)Ru-H pincer catalysts for the reduction of N2O by CO to produce N2 and CO2.	Nitrogen	246-248	pinin, desmosome associated protein	Homo sapiens	199-202
32988521-5	2020	Moreover, the addition of phytase linearly increased (P < 0.05) dietary protein, Ca, and phosphorus (P) utilization as well as nitrogen output, and excreta iron, copper, manganese, and zinc concentration quadratically increased (P < 0.05) as well as P output.	Nitrogen	127-135	putative glycerophosphoryl diester phosphodiesterase	Glycine max	26-33
32371117-7	2020	Furthermore, N1 nitrogen of the quinoline scaffold formed an essential hydrogen bond with the hinge region key amino acids Ala213 and Ala173 in AURKA and AURKB, respectively.	Nitrogen	16-24	aurora kinase B	Homo sapiens	154-159
33193713-8	2020	On the other hand, high NUE cultivar Mace responded to nitrogen stress by down-regulation of a stress-related gene annotated as beta-1,3-endoglucanase and pathogenesis-related protein (PR-4, PR-1) and up-regulation of MYB/SANT domain-containing RADIALIS (RAD)-like transcription factors.	Nitrogen	55-63	PR4	Triticum aestivum	185-189
29691239-2	2018	We aimed to investigate a potential role of UGT2B10 in N-glucosidation and to determine the transporters for the excretion of N-glucosides.	Nitrogen	55-56	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	44-51
32943810-3	2020	Positive GPD is therefore of considerable interest in relation to reducing the requirement for nitrogen fertilization for producing wheat for breadmaking.	Nitrogen	95-103	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	9-12
32171755-1	2020	Monocyte extravasation through the endothelial layer is a hallmark of atherosclerotic plaque development and is mediated by heavily N-glycosylated surface adhesion molecules, such as intercellular adhesion molecule-1 (ICAM-1).	Nitrogen	132-133	intercellular adhesion molecule 1	Homo sapiens	183-216
32171755-1	2020	Monocyte extravasation through the endothelial layer is a hallmark of atherosclerotic plaque development and is mediated by heavily N-glycosylated surface adhesion molecules, such as intercellular adhesion molecule-1 (ICAM-1).	Nitrogen	132-133	intercellular adhesion molecule 1	Homo sapiens	218-224
32171755-4	2020	Previous data from our lab has shown that endothelial inflammation produces multiple N-glycoforms of ICAM-1, and that a hypoglycosylated, or high-mannose (HM), form of ICAM-1 enhances adhesion of pro-inflammatory monocytes associated with more severe atherosclerosis and adverse cardiac events.	Nitrogen	85-86	intercellular adhesion molecule 1	Homo sapiens	101-107
29691239-10	2018	In conclusion, UGT2B10 was for the first time identified as an N-glucosidation enzyme.	Nitrogen	63-64	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	15-22
29437916-9	2018	We further demonstrate that this mobility shift in patients with GMPPB was due to abnormal N-linked glycosylation of beta-DG.	Nitrogen	91-92	GDP-mannose pyrophosphorylase B	Homo sapiens	65-70
32458917-2	2020	A recent report of O2-dependent aliphatic C-C bond cleavage at ambient temperature in Ni(ii) diketonate complexes supported by a tridentate nitrogen donor ligand [(MBBP)Ni(PhC(O)CHC(O)Ph)]Cl (7-Cl; MBBP = 2,6-bis(1-methylbenzimidazol-2-yl)pyridine) in the presence of NEt3 spurred our interest in further examining the chemistry of such complexes.	Nitrogen	140-148	splicing factor 1	Homo sapiens	164-168
32458917-2	2020	A recent report of O2-dependent aliphatic C-C bond cleavage at ambient temperature in Ni(ii) diketonate complexes supported by a tridentate nitrogen donor ligand [(MBBP)Ni(PhC(O)CHC(O)Ph)]Cl (7-Cl; MBBP = 2,6-bis(1-methylbenzimidazol-2-yl)pyridine) in the presence of NEt3 spurred our interest in further examining the chemistry of such complexes.	Nitrogen	140-148	splicing factor 1	Homo sapiens	198-202
32567913-7	2020	Our demonstration serves as a proof of concept for achieving efficient coherent control of electron-nuclear spin systems, such as nitrogen vacancy centers in diamond.	Nitrogen	130-138	spindlin 1	Homo sapiens	108-112
32166890-0	2020	Development and Structural Evaluation of N-alkylated Trans-2-phenylcyclopropylamine-based LSD1 Inhibitors.	Nitrogen	41-42	lysine demethylase 1A	Homo sapiens	90-94
32898471-1	2020	RNA m6A methylation is a post-transcriptional modification that occurs at the nitrogen-6 position of adenine.	Nitrogen	78-86	glycoprotein M6A	Homo sapiens	4-7
32699171-0	2020	A SnRK1-ZmRFWD3-Opaque2 Signaling Axis Regulates Diurnal Nitrogen Accumulation in Maize Seeds.	Nitrogen	57-65	regulatory protein opaque-2	Zea mays	16-23
32879731-6	2020	Meta-analysis of standardized mean difference (SMD) between severe and non-severe COVID-19 cases showed that CK-MB (SMD = 0.68,95%CI: 0.48;0.87; P-value:< 0.001), troponin I (SMD = 0.71, 95%CI:0.42;1.00; P-value:< 0.001), D-dimer (SMD = 0.54,95%CI:0.31;0.77; P-value:< 0.001), prothrombin time (SMD = 0.48, 95%CI:0.23;0.73; P-value: < 0.001), procalcitonin (SMD = 0.72, 95%CI: 0.34;1,11; P-value:< 0.001), interleukin-6 (SMD = 0.93, 95%CI: 0.25;1.61;P-value: 0.007),C-reactive protein (CRP) (SMD = 1.34, 95%CI:0.83;1.86; P-value:< 0.001), ALAT (SMD = 0.53, 95%CI: 0.34;0,71; P-value:< 0.001), ASAT (SMD = 0.96, 95%CI: 0.58;1.34; P-value: < 0.001), LDH (SMD = 1.36, 95%CI: 0.75;1.98; P-value:< 0.001), CK (SMD = 0.48, 95%CI: 0.10;0.87; P-value:0.01), total bilirubin (SMD = 0.32, 95%CI: 0.18;0.47;P-value: < 0.001), gamma-GT (SMD = 1.03, 95%CI: 0.83;1.22; P-value: < 0.001), myoglobin (SMD = 1.14, 95%CI: 0.81;1.47; P-value:< 0.001), blood urea nitrogen (SMD = 0.32, 95%CI: 0.18;0.47;P-value:< 0.001) and Creatininemia (SMD = 0.18, 95%CI: 0.01;0.35; P-value:0.04) were significantly more elevated in severe cases, in opposition to lymphocyte count (SMD = -0.57, 95%CI:-0.71; - 0.42; P-value: < 0.001) and proportion of lymphocytes (SMD = -0.81, 95%CI: - 1.12; - 0.49; P-value:< 0.001) which were found to be significantly lower in severe patients with other biomarker such as thrombocytes (SMD = -0.26, 95%CI: - 0.48; - 0.04; P-value:0.02), eosinophils (SMD = - 0.28, 95%CI:-0.50; - 0.06; P-value:0.01), haemoglobin (SMD = -0.20, 95%CI: - 0.37,-0.03; P-value:0.02), albuminemia (SMD-1.67,95%CI -2.40; - 0.94; P-value:< 0.001), which were also lower.	Nitrogen	944-952	cytidine/uridine monophosphate kinase 1	Homo sapiens	109-111
31458846-6	2018	The atomic charge on the pyridine nitrogen atom [rho(Npy)] was extracted from the natural orbital population analysis.	Nitrogen	34-42	neuropeptide Y	Homo sapiens	53-56
32616672-3	2020	N-glycosylation mapping and biophysical assays revealed that uromodulin acts as a multivalent ligand for the bacterial type 1 pilus adhesin, presenting specific epitopes on the regularly spaced arms.	Nitrogen	0-1	uromodulin	Homo sapiens	61-71
31573704-3	2020	Recent advances in 2D electrocatalysts are reviewed for emerging applications that utilize naturally existing H2 O, N2 , O2 , Cl- (seawater) and CH4 (natural gas) as reactants for nitrogen reduction (N2   NH3 ), two-electron oxygen reduction (O2   H2 O2 ), chlorine evolution (Cl-   Cl2 ), and methane partial oxidation (CH4   CH3 OH) reactions to generate NH3 , H2 O2 , Cl2 , and CH3 OH.	Nitrogen	180-188	endogenous retrovirus group W member 5	Homo sapiens	283-286
31573704-3	2020	Recent advances in 2D electrocatalysts are reviewed for emerging applications that utilize naturally existing H2 O, N2 , O2 , Cl- (seawater) and CH4 (natural gas) as reactants for nitrogen reduction (N2   NH3 ), two-electron oxygen reduction (O2   H2 O2 ), chlorine evolution (Cl-   Cl2 ), and methane partial oxidation (CH4   CH3 OH) reactions to generate NH3 , H2 O2 , Cl2 , and CH3 OH.	Nitrogen	180-188	endogenous retrovirus group W member 5	Homo sapiens	371-374
32032660-3	2020	The treatment with A + N (or camptothecin) strongly upregulated caspase-1 and its two activators: IFI16 and NLRP1, however, caspase-1 activation was not detected.	Nitrogen	23-24	interferon gamma inducible protein 16	Homo sapiens	98-103
32691774-1	2020	The stereoselective sulfur-nitrogen difunctionalization (aminosulfonylation) across the alkyne framework in a syn mode is accomplished using sodium sulfinates and azoles, in the presence of I2/base.	Nitrogen	27-35	synemin	Homo sapiens	110-113
29572863-7	2018	N-glucuronidation of norketamine was studied in vitro with liver microsomes of different species and the single human enzyme UGT1A4.	Nitrogen	0-1	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	125-131
32678616-3	2020	(H2O)n (n=1,2,3) were first optimized at the MP2/6-311++G(d,p) and B3LYP-D3BJ/def2-TZVP levels of theory.	Nitrogen	5-6	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	69-72
31612495-8	2020	Furthermore, we found that MKP1 overexpression is associated with inactivation of mitogen-activated protein kinase-c-Jun N-terminal kinase (MAPK-JNK) pathway.	Nitrogen	121-122	dual specificity phosphatase 1	Mus musculus	27-31
31612495-8	2020	Furthermore, we found that MKP1 overexpression is associated with inactivation of mitogen-activated protein kinase-c-Jun N-terminal kinase (MAPK-JNK) pathway.	Nitrogen	121-122	mitogen-activated protein kinase 8	Mus musculus	145-148
29765039-3	2018	Here, we demonstrate that epithelial-mesenchymal transition (EMT) enriches PD-L1 in CSCs by the EMT/beta-catenin/STT3/PD-L1 signaling axis, in which EMT transcriptionally induces N-glycosyltransferase STT3 through beta-catenin, and subsequent STT3-dependent PD-L1 N-glycosylation stabilizes and upregulates PD-L1.	Nitrogen	179-180	CD274 molecule	Homo sapiens	75-80
32060048-9	2020	Intriguingly, truncation of the N-terminus reduced sigma1R to apparent monomer.	Nitrogen	32-33	sigma non-opioid intracellular receptor 1	Rattus norvegicus	51-58
32060048-20	2020	Further, mutational analysis revealed a crucial role of its N-terminal domain in sigma1R multimerization.	Nitrogen	60-61	sigma non-opioid intracellular receptor 1	Rattus norvegicus	81-88
32719124-3	2020	By engineering a glycoprotein-derived epitope to contain an N-linked glycosylation site, we determined that optimal CD8+ T cell expansion and function were induced by the peptides that are rapidly produced from the exceedingly minor fraction of protein mislocalized to the cytosol.	Nitrogen	60-61	CD8a molecule	Homo sapiens	116-119
31376131-2	2020	Salicylic acid was selected as a model emerging pollutant and powders of nitrogen-doped titanium dioxide (N-TiO2) and TiO2 were prepared by the sol-gel process, using TiO2 P-25 Degussa as benchmark.	Nitrogen	73-81	tubulin polymerization promoting protein	Homo sapiens	172-176
29765039-3	2018	Here, we demonstrate that epithelial-mesenchymal transition (EMT) enriches PD-L1 in CSCs by the EMT/beta-catenin/STT3/PD-L1 signaling axis, in which EMT transcriptionally induces N-glycosyltransferase STT3 through beta-catenin, and subsequent STT3-dependent PD-L1 N-glycosylation stabilizes and upregulates PD-L1.	Nitrogen	179-180	catenin beta 1	Homo sapiens	100-112
32430722-0	2020	Diclofenac shifts the role of root glutamine synthetase and glutamate dehydrogenase for maintaining nitrogen assimilation and proline production at the expense of shoot carbon reserves in Solanum lycopersicum L. The continuous increase of the human population worldwide has led to an increase of pharmaceuticals" consumption, such as diclofenac (DCF), a widely used non-steroidal anti-inflammatory drug (NSAID), that is not removed by wastewater treatment processes.	Nitrogen	100-108	glutamine synthetase	Solanum lycopersicum	35-55
32407958-3	2020	The interactions between reactive oxygen species (ROS)/reactive nitrogen species (RNS) and innate immune receptors such as TLR2/4, NOD-like receptor, RAGE, and scavenger receptors are crucial pathological mechanisms that amplify brain damage during cerebral ischemic brain injury.	Nitrogen	64-72	advanced glycosylation end-product specific receptor	Homo sapiens	150-154
32608481-9	2020	Neutralization of HMGB1 attenuated IR-induced increases in plasma creatinine, blood urea nitrogen (BUN), inflammation, tubular damage and tubular cell death only in male SHR.	Nitrogen	89-97	high mobility group box 1	Rattus norvegicus	18-23
32090830-3	2020	The experimental results showed the blue AG-PBR to be more effective in removing chemical oxygen demand (COD), total nitrogen (TN) and ammonia nitrogen (NH3-N) and generating biomass productivity than those of the red AG-PBR (P &lt; 0.05).	Nitrogen	143-151	translocator protein	Homo sapiens	44-47
32161097-6	2020	The P2 N-glycosylated extracellular membrane attack complex/perforin domain and the P2 domain independently associate with the extracellular regions of IFNAR1 and IFNAR2, respectively, in resting MEFs.	Nitrogen	7-8	interferon (alpha and beta) receptor 2	Mus musculus	163-169
32029273-2	2020	Using this strategy, we previously knocked-in the EGFP coding sequence into the N-terminal region of the beta-actin gene specifically in the pyramidal neurons in layer 2/3 of the somatosensory cortex.	Nitrogen	80-81	actin, beta	Mus musculus	105-115
29765039-3	2018	Here, we demonstrate that epithelial-mesenchymal transition (EMT) enriches PD-L1 in CSCs by the EMT/beta-catenin/STT3/PD-L1 signaling axis, in which EMT transcriptionally induces N-glycosyltransferase STT3 through beta-catenin, and subsequent STT3-dependent PD-L1 N-glycosylation stabilizes and upregulates PD-L1.	Nitrogen	179-180	CD274 molecule	Homo sapiens	118-123
31814109-6	2020	Here we use the N-terminally truncated version of the bovine NADPH-dependent cytochrome P450 reductase (bCPR-27 ) and co-expression of microsomal cytochrome b 5 (ii) enhancing substrate access to the heme by modification of the CYP21A2 substrate access channel and (iii) circumventing substrate inhibition which is presumed to be the main limiting factor of the presented system by developing an improved fed-batch protocol.	Nitrogen	16-17	steroid 21-hydroxylase	Bos taurus	228-235
29765039-3	2018	Here, we demonstrate that epithelial-mesenchymal transition (EMT) enriches PD-L1 in CSCs by the EMT/beta-catenin/STT3/PD-L1 signaling axis, in which EMT transcriptionally induces N-glycosyltransferase STT3 through beta-catenin, and subsequent STT3-dependent PD-L1 N-glycosylation stabilizes and upregulates PD-L1.	Nitrogen	179-180	CD274 molecule	Homo sapiens	118-123
29431199-0	2018	N-glycosylation by N-acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin beta1 and promotes HCC metastasis.	Nitrogen	0-1	basigin (Ok blood group)	Homo sapiens	81-86
31916136-3	2020	Here we report the 1H, 15 N and 13C resonance assignments of RalA in its active form bound to the GTP analogue GMPPNP.	Nitrogen	26-27	RAS like proto-oncogene A	Homo sapiens	61-65
32490669-6	2020	With Pd(OAc)2 as the catalyst and Cu(OTf)2 as the co-catalyst, the N-directed C-H alkenylation becomes preferred due to the strong coordination of the nitrogen atom to the copper center.	Nitrogen	151-159	POU class 2 homeobox 2	Homo sapiens	34-42
29431199-0	2018	N-glycosylation by N-acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin beta1 and promotes HCC metastasis.	Nitrogen	0-1	basigin (Ok blood group)	Homo sapiens	87-94
32387086-7	2020	It was found that CL/F increases with serum creatinine and uric acid levels and V1/F is modified by blood urea nitrogen and the UGT1A9 genotype.	Nitrogen	111-119	cytokine receptor like factor 1	Homo sapiens	18-22
29431199-2	2018	In the current study, we report that GnT-V-mediated N-glycosylation of CD147/basigin, a tumor-associated glycoprotein that carries beta1,6-N-acetylglucosamine (beta1,6-GlcNAc) glycans, is upregulated during TGF-beta1-induced epithelial-to-mesenchymal transition (EMT), which correlates with tumor metastasis in patients with hepatocellular carcinoma (HCC).	Nitrogen	52-53	basigin (Ok blood group)	Homo sapiens	71-76
29431199-2	2018	In the current study, we report that GnT-V-mediated N-glycosylation of CD147/basigin, a tumor-associated glycoprotein that carries beta1,6-N-acetylglucosamine (beta1,6-GlcNAc) glycans, is upregulated during TGF-beta1-induced epithelial-to-mesenchymal transition (EMT), which correlates with tumor metastasis in patients with hepatocellular carcinoma (HCC).	Nitrogen	52-53	basigin (Ok blood group)	Homo sapiens	77-84
29725404-12	2018	By contrast, co-treatment of PLC/PRF/5 cells with 500 micromol/l NaHS and 20 micromol/l NS-398 inhibited the NaHS-induced increase in the expression level of p-STAT3.	Nitrogen	88-90	heparan sulfate proteoglycan 2	Homo sapiens	29-32
32451662-3	2020	MAGT1 is now confirmed as a non-catalytic subunit of the oligosaccharyltransferase complex and facilitates Asparagine (N)-linked glycosylation of specific substrates, making XMEN a congenital disorder of glycosylation manifesting as a combined immune deficiency.	Nitrogen	118-121	magnesium transporter 1	Homo sapiens	0-5
32451662-3	2020	MAGT1 is now confirmed as a non-catalytic subunit of the oligosaccharyltransferase complex and facilitates Asparagine (N)-linked glycosylation of specific substrates, making XMEN a congenital disorder of glycosylation manifesting as a combined immune deficiency.	Nitrogen	118-121	magnesium transporter 1	Homo sapiens	174-178
29706962-2	2018	These Fab glycans are acquired following introduction of N-glycosylation sites during somatic hypermutation and contribute to antibody diversification.	Nitrogen	57-58	FA complementation group B	Homo sapiens	6-9
32216104-2	2020	The deficiency of ATP6AP1, an accessory subunit of the vacuolar H+ -ATPase, is a recently characterized N- and O-glycosylation defect manifesting with immunodeficiency, hepatopathy and cognitive impairment.	Nitrogen	104-105	ATPase H+ transporting accessory protein 1	Homo sapiens	18-25
32564227-4	2020	Particular attention is paid to NAD+ depletion as a core cause of pathology; detrimental effects of raised ROS and reactive nitrogen species on ATP and NADPH generation; detrimental effects of oxidative and nitrosative stress on the glutathione and thioredoxin systems; and the NAD+-induced signalling cascade, including the roles of SIRT1, SIRT3, PGC-1alpha, the FOXO family of transcription factors, Nrf1 and Nrf2.	Nitrogen	124-132	2,4-dienoyl-CoA reductase 1	Homo sapiens	152-157
29367433-7	2018	N-glycans presented in each chromatographic peak were elucidated using MALDI-TOF/TOF-MS. We detected changes in the N-glycosylation pattern of the lysosomal glycocalyx of NPC1-null versus wt cells which involved high-mannose and sialylated N-glycans.	Nitrogen	0-1	NPC intracellular cholesterol transporter 1	Homo sapiens	171-175
32398320-0	2020	The root foraging response under low nitrogen depends on DWARF1-mediated brassinosteroid biosynthesis.	Nitrogen	37-45	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	57-63
32398320-4	2020	By performing a genome-wide association study in Arabidopsis thaliana, we identify here that non-coding variations of the brassinosteroid (BR) biosynthesis gene DWARF 1 (DWF1) leads to variation of DWF1 transcript level that contributes to natural variation of root elongation under low N.	Nitrogen	287-288	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	161-168
29547588-6	2018	These results expand our understanding of the importance of N-substituent structural variations in the opioid receptor profile of cis-(-)-N-normetazocine derivatives and identify a new MOR agonist useful for the development of novel opioid analgesics for pain treatment.	Nitrogen	60-61	opioid receptor mu 1	Homo sapiens	185-188
32398320-4	2020	By performing a genome-wide association study in Arabidopsis thaliana, we identify here that non-coding variations of the brassinosteroid (BR) biosynthesis gene DWARF 1 (DWF1) leads to variation of DWF1 transcript level that contributes to natural variation of root elongation under low N.	Nitrogen	287-288	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	170-174
32398320-4	2020	By performing a genome-wide association study in Arabidopsis thaliana, we identify here that non-coding variations of the brassinosteroid (BR) biosynthesis gene DWARF 1 (DWF1) leads to variation of DWF1 transcript level that contributes to natural variation of root elongation under low N.	Nitrogen	287-288	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	198-202
32398320-5	2020	Besides DWF1, low N also upregulates other central BR biosynthesis genes including CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD), DWARF 4 (DWF4) and BRASSINOSTEROID-6-OXIDASE 2 (BR6OX2).	Nitrogen	18-19	Cytochrome P450 superfamily protein	Arabidopsis thaliana	126-133
32398320-5	2020	Besides DWF1, low N also upregulates other central BR biosynthesis genes including CONSTITUTIVE PHOTOMORPHOGENIC DWARF (CPD), DWARF 4 (DWF4) and BRASSINOSTEROID-6-OXIDASE 2 (BR6OX2).	Nitrogen	18-19	Cytochrome P450 superfamily protein	Arabidopsis thaliana	135-139
32398320-7	2020	Moreover, we show that low N-induced root elongation is associated with above-ground N contents and that overexpression of DWF1 significantly improves plant growth and overall N accumulation.	Nitrogen	27-28	cell elongation protein / DWARF1 / DIMINUTO (DIM)	Arabidopsis thaliana	123-127
32610141-3	2020	Our study unveils a specific N-glycosylation pattern used by a chaperone, Glucose-regulated protein 94 (GRP94), to alter its conformational fitness and stabilize a state most permissive for stable interactions with proteins at the plasma membrane.	Nitrogen	29-30	heat shock protein 90 beta family member 1	Homo sapiens	74-102
32610141-3	2020	Our study unveils a specific N-glycosylation pattern used by a chaperone, Glucose-regulated protein 94 (GRP94), to alter its conformational fitness and stabilize a state most permissive for stable interactions with proteins at the plasma membrane.	Nitrogen	29-30	heat shock protein 90 beta family member 1	Homo sapiens	104-109
29564399-10	2018	In S. cerevisiae, Dal81 is a positive regulator of acquisition of nitrogen from GABA, allantoin, urea, and leucine, and it is required for maximal induction of expression of the relevant pathway genes.	Nitrogen	66-74	Dal81p	Saccharomyces cerevisiae S288C	18-23
32559193-2	2020	The extensive N-linked glycosylation on Env is an important consideration as it may affect efficacy, stability, and expression yields.	Nitrogen	14-15	endogenous retrovirus group K member 20	Homo sapiens	40-43
29564399-12	2018	Instead, Dal81 represses arginine synthesis during growth under preferred nitrogen conditions.	Nitrogen	74-82	Dal81p	Saccharomyces cerevisiae S288C	9-14
29444815-1	2018	N-glycosylation is a common posttranslational modification of secreted and membrane proteins, catalyzed by the two enzymatic isoforms of the oligosaccharyltransferase, STT3A and STT3B.	Nitrogen	0-1	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	168-173
32545597-3	2020	The in vivo metabolic regulation of AOX activity by phosphorus (P) and nitrogen (N) and during plant symbioses with Arbuscular mycorrhizal fungi (AMF) and Rhizobium bacteria is still not fully understood.	Nitrogen	71-79	acyl-CoA oxidase 1	Homo sapiens	36-39
32545597-3	2020	The in vivo metabolic regulation of AOX activity by phosphorus (P) and nitrogen (N) and during plant symbioses with Arbuscular mycorrhizal fungi (AMF) and Rhizobium bacteria is still not fully understood.	Nitrogen	81-82	acyl-CoA oxidase 1	Homo sapiens	36-39
29444815-1	2018	N-glycosylation is a common posttranslational modification of secreted and membrane proteins, catalyzed by the two enzymatic isoforms of the oligosaccharyltransferase, STT3A and STT3B.	Nitrogen	0-1	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	178-183
32545597-5	2020	We also highlight the need for the identification of which metabolic regulatory factors of AOX activity are related to N availability and nitrogen-fixing legume-rhizobia symbiosis in order to improve our understanding of N assimilation and biological nitrogen fixation.	Nitrogen	119-120	acyl-CoA oxidase 1	Homo sapiens	91-94
32545597-5	2020	We also highlight the need for the identification of which metabolic regulatory factors of AOX activity are related to N availability and nitrogen-fixing legume-rhizobia symbiosis in order to improve our understanding of N assimilation and biological nitrogen fixation.	Nitrogen	138-146	acyl-CoA oxidase 1	Homo sapiens	91-94
29494673-0	2018	The bovine TRPV3 as a pathway for the uptake of Na+, Ca2+, and NH4+ Absorption of ammonia from the gastrointestinal tract results in problems that range from hepatic encephalopathy in humans to poor nitrogen efficiency of cattle with consequences for the global climate.	Nitrogen	199-207	transient receptor potential cation channel subfamily V member 3	Bos taurus	11-16
32545597-5	2020	We also highlight the need for the identification of which metabolic regulatory factors of AOX activity are related to N availability and nitrogen-fixing legume-rhizobia symbiosis in order to improve our understanding of N assimilation and biological nitrogen fixation.	Nitrogen	221-222	acyl-CoA oxidase 1	Homo sapiens	91-94
32545597-5	2020	We also highlight the need for the identification of which metabolic regulatory factors of AOX activity are related to N availability and nitrogen-fixing legume-rhizobia symbiosis in order to improve our understanding of N assimilation and biological nitrogen fixation.	Nitrogen	251-259	acyl-CoA oxidase 1	Homo sapiens	91-94
28480569-6	2018	CP-d/n ATF5 was found to decrease cell viability in canine glioma cell lines in vitro in a dose-dependent manner.	Nitrogen	5-6	activating transcription factor 5	Canis lupus familiaris	7-11
32109361-1	2020	Medication-related osteonecrosis of the jaw (MRONJ) is a rare intraoral lesion that occurs in patients undergoing long-term and/or high-dose therapy with nitrogen-containing bisphosphonates, a RANKL inhibitor, antiangiogenic agents, or mTOR inhibitors.	Nitrogen	154-162	TNF superfamily member 11	Homo sapiens	193-198
32766444-2	2020	The emergence of nitrogen-vacancy (NV) centers in diamond, serving as an atomic-sized magnetometer, has promoted this technique to single-spin level, even under ambient conditions.	Nitrogen	17-25	spindlin 1	Homo sapiens	138-142
29217529-4	2018	In addition, the N-glycosylation-defective FAM198B mutants generated by site-directed mutagenesis were used to study protein stability and subcellular localization of FAM198B.	Nitrogen	17-18	golgi associated kinase 1B	Homo sapiens	43-50
32528505-6	2020	Based on the observation in the double mutants fugu5-1 ppa1 and fugu5-1 ppa4 of more severe atrophy compared to fugu5-1, the nitrogen-dependent phenotype might be linked to PPi metabolism.	Nitrogen	125-133	pyrophosphorylase 4	Arabidopsis thaliana	72-76
29217529-4	2018	In addition, the N-glycosylation-defective FAM198B mutants generated by site-directed mutagenesis were used to study protein stability and subcellular localization of FAM198B.	Nitrogen	17-18	golgi associated kinase 1B	Homo sapiens	167-174
32434850-0	2020	ATRAID regulates the action of nitrogen-containing bisphosphonates on bone.	Nitrogen	31-39	all-trans retinoic acid induced differentiation factor	Homo sapiens	0-6
29450655-5	2018	They interact with DELLA proteins to induce the expression of NIN in nitrogen fixing symbiosis or RAM1 in mycorrhizal symbiosis.	Nitrogen	69-77	ninein	Homo sapiens	62-65
32408549-7	2020	The MAPK cascades could be regulating N assimilation, since it has been described that the phosphorylation of NR by MAPK6 promotes NO production in Arabidopsis thaliana.	Nitrogen	38-39	MAP kinase 6	Arabidopsis thaliana	116-121
32371889-4	2020	Instead, biochemical and microscopy studies reveal that N-GSDMD in neutrophils predominantly associates with azurophilic granules and LC3+ autophagosomes.	Nitrogen	56-57	gasdermin D	Mus musculus	58-63
29324345-1	2018	In the present study, a series of multi-target N-substituted cyclic imide derivatives which possessed potent dopamine D2, serotonin 5-HT1A and 5-HT2A receptors properties were synthesized and evaluated as potential antipsychotics.	Nitrogen	47-48	5-hydroxytryptamine receptor 1A	Homo sapiens	132-144
32057422-1	2020	Farnesyl pyrophosphate synthase (FPPS) is a crucial enzyme for the synthesis of isoprenoids and the key target of nitrogen-containing bisphosphonates (N-BPs).	Nitrogen	114-122	farnesyl diphosphate synthase	Homo sapiens	0-31
32057422-1	2020	Farnesyl pyrophosphate synthase (FPPS) is a crucial enzyme for the synthesis of isoprenoids and the key target of nitrogen-containing bisphosphonates (N-BPs).	Nitrogen	114-122	farnesyl diphosphate synthase	Homo sapiens	33-37
32057752-6	2020	In case of anionic liposomes composed of dipalmitoylphosphatidylcholine (DPPC) and cardiolipin (CL2-) the electrostatic interaction of negatively charged nitrogen in heterocycle moiety of moxifloxacin with cardiolipin phosphate groups is a crucial factor for stable complex formation.	Nitrogen	154-162	endogenous retrovirus group W member 5	Homo sapiens	96-99
29434741-11	2018	Compared with that in the HRTx+NS group, serum levels and graft tissue mRNA expression of IFN-gamma and IL-2 were decreased in the HRTx+CXCL10 Abs group, while TGF-beta mRNA was significantly increased but the serum concentration was not significantly affected.	Nitrogen	31-33	interferon gamma	Rattus norvegicus	90-99
31897962-9	2020	Plasma FGF23 was significantly associated with LVMI in TAK patients [beta = 0.402, 95% confidence interval (CI) 0.032-0.301, P = 0.016], after adjusting for age, gender, disease duration, angiographic type (angiographic type V vs. non-angiographic type V), the presence of cardiovascular events and hypertension, and serum N-terminal pro-B-type natriuretic peptide in the multivariate linear regression.	Nitrogen	323-324	fibroblast growth factor 23	Homo sapiens	7-12
31889430-1	2020	BACKGROUND: Fibrin polymerization, following fibrinopeptides A and B (FpA, FpB) cleavage, relies on newly exposed alpha- and beta-chains N-termini (GPR, GHR; A-, B-knobs, respectively) engaging pre-existent a and b pockets in other fibrin(ogen) molecules" gamma- and (B)beta-chains C-terminal regions.	Nitrogen	8-9	growth hormone receptor	Homo sapiens	153-156
29434741-11	2018	Compared with that in the HRTx+NS group, serum levels and graft tissue mRNA expression of IFN-gamma and IL-2 were decreased in the HRTx+CXCL10 Abs group, while TGF-beta mRNA was significantly increased but the serum concentration was not significantly affected.	Nitrogen	31-33	interleukin 2	Rattus norvegicus	104-108
31793100-0	2020	The NIN-like protein 5 (ZmNLP5) transcription factor is involved in modulating the nitrogen response in maize.	Nitrogen	83-91	Protein RKD4	Zea mays	24-30
32179648-2	2020	The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell.	Nitrogen	204-212	NAD synthetase 1	Homo sapiens	16-30
31793100-2	2020	Here, we report the functional characterization of a maize NIN-like protein ZmNLP5 as a central hub in a molecular network associated with N metabolism.	Nitrogen	59-60	Protein RKD4	Zea mays	76-82
29354815-0	2018	CoP nanoparticles anchored on N,P-dual-doped graphene-like carbon as a catalyst for water splitting in non-acidic media.	Nitrogen	30-31	caspase recruitment domain family member 16	Homo sapiens	0-3
31793100-4	2020	Under limited N supply, compared with that of wild-type (WT) seedlings, the zmnlp5 mutant seedlings accumulated less nitrate and nitrite in the root tissues and ammonium in the shoot tissues.	Nitrogen	14-15	Protein RKD4	Zea mays	76-82
31793100-5	2020	The zmnlp5 mutant plants accumulated less nitrogen than the WT plants in the ear leaves and seed kernels.	Nitrogen	42-50	Protein RKD4	Zea mays	4-10
31793100-7	2020	In the zmnlp5 mutant plants, loss of the ZmNLP5 function led to changes in expression for a significant number of genes involved in N signalling and metabolism.	Nitrogen	43-44	Protein RKD4	Zea mays	7-13
31793100-9	2020	Interestingly, a natural loss-of-function allele of ZmNLP5 in Mo17 conferred less N accumulation in the ear leaves and seed kernels resembling that of the zmnlp5 mutant plants.	Nitrogen	54-55	Protein RKD4	Zea mays	155-161
31603583-0	2020	Crystal and Solution Structures of Human Oncoprotein Musashi-2 N-terminal RNA Recognition Motif 1.	Nitrogen	63-64	musashi RNA binding protein 2	Homo sapiens	53-62
32179648-2	2020	The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell.	Nitrogen	204-212	brain expressed X-linked 3	Homo sapiens	38-42
32179648-2	2020	The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell.	Nitrogen	204-212	brain expressed X-linked 3	Homo sapiens	171-175
32179648-2	2020	The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell.	Nitrogen	528-536	NAD synthetase 1	Homo sapiens	16-30
32179648-2	2020	The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell.	Nitrogen	528-536	brain expressed X-linked 3	Homo sapiens	38-42
32179648-2	2020	The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD+ biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD+ Some members of the NadE family use l-glutamine as a nitrogen donor and are named NadEGln Previous gene neighborhood analysis has indicated that the bacterial nadE gene is frequently clustered with the gene encoding the regulatory signal transduction protein PII, suggesting a functional relationship between these proteins in response to the nutritional status and the carbon/nitrogen ratio of the bacterial cell.	Nitrogen	528-536	brain expressed X-linked 3	Homo sapiens	171-175
32087424-8	2020	Furthermore, the difference in n-3 PUFA levels detected at baseline between depressed and non-depressed participants tended to dissipate over 6 years (depression-by-time estimate: p = .011).	Nitrogen	24-25	pumilio RNA binding family member 3	Homo sapiens	35-39
32685345-1	2020	Background: Phosphomannomutase 2 deficiency (PMM2-CDG) affects glycosylation pathways such as the N-glycosylation pathway, resulting in loss of function of multiple proteins.	Nitrogen	98-99	phosphomannomutase 2	Homo sapiens	12-32
32685345-1	2020	Background: Phosphomannomutase 2 deficiency (PMM2-CDG) affects glycosylation pathways such as the N-glycosylation pathway, resulting in loss of function of multiple proteins.	Nitrogen	98-99	phosphomannomutase 2	Homo sapiens	45-49
31661268-0	2020	Structure-Activity Relationships for a series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines at the dopamine transporter: functionalizing the terminal nitrogen affects affinity, selectivity and metabolic stability.	Nitrogen	165-173	solute carrier family 6 member 3	Homo sapiens	114-134
31996378-9	2020	Co-precipitation assays revealed that Fry uses its N-terminal 1-2400 amino-acid-long region to bind to YAP.	Nitrogen	51-52	FRY microtubule binding protein	Homo sapiens	38-41
31996378-10	2020	Expression of full-length FRY or its 1-2400 N-terminal fragment restored YAP cytoplasmic localization in FRY-knockout cells.	Nitrogen	44-45	FRY microtubule binding protein	Homo sapiens	26-29
31804721-0	2020	Role of the N-Terminal Transmembrane Helix Contacts in the Activation of FGFR3.	Nitrogen	12-13	fibroblast growth factor receptor 3	Homo sapiens	73-78
32383959-4	2020	We further exploit the large magnetic moment to mass ratio of this mechanical oscillator to couple its motion to the spin degrees of freedom of an individual nitrogen vacancy center in diamond.	Nitrogen	158-166	spindlin 1	Homo sapiens	117-121
29354815-2	2018	CoP nanoparticles anchored on N,P-dual-doped mesoporous graphene-like carbon (CoP@NPMG) acts as an outstanding bifunctional electrocatalyst for both the hydrogen evolution reaction and the oxygen evolution reaction over a wide pH range.	Nitrogen	30-31	caspase recruitment domain family member 16	Homo sapiens	0-3
29354815-2	2018	CoP nanoparticles anchored on N,P-dual-doped mesoporous graphene-like carbon (CoP@NPMG) acts as an outstanding bifunctional electrocatalyst for both the hydrogen evolution reaction and the oxygen evolution reaction over a wide pH range.	Nitrogen	30-31	caspase recruitment domain family member 16	Homo sapiens	78-81
29410815-5	2018	The results show that NPC-1-900/CNTF electrode exhibits an exceptional areal capacitance of 121.5 mF cm-2 compared to that of PC-900/CNTF electrode (22.8 mF cm-2) at 5 mV s-1 in a three-electrode system, indicating that the incorporation of nitrogen is beneficial to the electrochemical properties of nanoporous carbon.	Nitrogen	241-249	NPC intracellular cholesterol transporter 1	Homo sapiens	22-27
32340215-5	2020	Our results showed that this variant reduces protein stability and impairs the post-translational processing (N-linked glycosylation) and subcellular localization of MAG, thereby associating a loss of protein function with the phenotype.	Nitrogen	110-111	myelin associated glycoprotein	Homo sapiens	166-169
29719608-6	2018	Mechanistically, beta3GnT8 modulated the N-glycosylation patterns of CD147 and altered the polylactosamine structures in HCC cells by physically interacting with CD147.	Nitrogen	41-42	basigin (Ok blood group)	Homo sapiens	69-74
32382573-12	2020	To further elucidate the overall role of n-3 PUFA on muscle damage in this area, large-scale RCTs are still needed.	Nitrogen	41-42	pumilio RNA binding family member 3	Homo sapiens	45-49
32316603-12	2020	Both human OST complexes, OST-A (with STT3A) and OST-B (containing STT3B), are involved in the N-linked glycosylation of proteins in the ER.	Nitrogen	95-96	solute carrier family 51 subunit alpha	Homo sapiens	26-31
29205945-2	2018	New hybrids of indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and DNA alkylating nitrogen mustards that respectively target IDO1 and DNA were rationally designed.	Nitrogen	82-90	indoleamine 2,3-dioxygenase 1	Homo sapiens	125-129
32357057-2	2020	Specifically, using the nitrogen-vacancy (NV) color center in diamond, we demonstrate control of a proximal ^{14}N nuclear spin via an all-optical Raman technique.	Nitrogen	24-32	spindlin 1	Homo sapiens	123-127
32090830-3	2020	The experimental results showed the blue AG-PBR to be more effective in removing chemical oxygen demand (COD), total nitrogen (TN) and ammonia nitrogen (NH3-N) and generating biomass productivity than those of the red AG-PBR (P &lt; 0.05).	Nitrogen	117-125	translocator protein	Homo sapiens	44-47
29965664-7	2018	The inorganic nitrogen was the dominant species of DTN in Qingdao and over the Yellow and Bohai Sea (YBS), accounting for 67% and 75% of DTN, respectively.	Nitrogen	14-22	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	96-99
31985880-1	2020	OBJECTIVES: To comprehensively investigate the role of the N6-methyladeonsine (m6A) erasers ALKBH5 and FTO in clear cell renal carcinoma (ccRCC), other RCC subtypes and Oncocytoma with respect to prognostic value and biomarker potential.	Nitrogen	59-77	glycoprotein M6A	Homo sapiens	79-82
31869857-7	2020	Compared to HTK, HTK-N induced a decreased extent of proximal tubule swelling (48.3+-1.6 microm vs. 52.3+-1.1 microm, p=0.05) and decreased cytochrome c release (0.26+-0.04 vs. 0.46+-0.08, p=0.04) without reaching statistical significance due to Bonferroni correction.	Nitrogen	21-22	cytochrome c	Sus scrofa	140-152
29309433-5	2018	ALG1 is presumed to be involved in the regulation of the protein N-glycosylation.	Nitrogen	65-66	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	0-4
31869857-8	2020	Comparing baseline and postreperfusion levels, the hemoglobin (Hb) and blood calcium levels were lower in HTK-N (Hbbaseline : 6.0+-0.6 mmol/L, Hbreperfusion : 6.2+-0.7 mmol/L, p=0.12; Ca2+ baseline : 1.36+-0.05mmol/L, Ca2+ reperfusion : 1.28+-0.05mmol/L, p=0.16) compared to the HTK group (Hbbaseline : 5.9+-0.4 mmol/L, Hbreperfusion : 4.7+-0.8 mmol/L, p&lt;0.01; Ca2+ baseline : 1.34+-0.07mmol/L, Ca2+ reperfusion : 1.24+-0.06mmol/L, p&lt;0.01).	Nitrogen	110-111	HGB	Sus scrofa	51-61
31915290-7	2020	Initiation is also elevated at certain NCCs initiating N-terminal extensions, including those that direct mitochondrial localization of the GRS1 and ALA1 products, and at a small set of main CDS AUG codons with especially poor context, including that of eIF1 itself.	Nitrogen	39-40	glycine--tRNA ligase	Saccharomyces cerevisiae S288C	140-144
28892050-8	2018	These functions were modulated by N-acetylglucosaminyltransferase 5 (MGAT5) which mediated N-glycosylation at Asn256 (N256) of CEACAM6.	Nitrogen	34-35	CEA cell adhesion molecule 6	Homo sapiens	127-134
32179690-6	2020	The structure, along with additional high-resolution crystal structures of several analogs in complex with RalA, confirm the importance of key hydrogen bond anchors between compound sulfone oxygen atoms and Ral backbone nitrogen atoms.	Nitrogen	220-228	RAS like proto-oncogene A	Homo sapiens	107-111
32179690-6	2020	The structure, along with additional high-resolution crystal structures of several analogs in complex with RalA, confirm the importance of key hydrogen bond anchors between compound sulfone oxygen atoms and Ral backbone nitrogen atoms.	Nitrogen	220-228	RAN pseudogene 1	Homo sapiens	107-110
32141499-1	2020	Fucosyltransferase 8 (FUT8) and beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) are glycosyltransferases (GTases) that catalyze alpha1,6-fucosylation and alpha2,6-sialylation, respectively, in the mammalian N-glycosylation pathway.	Nitrogen	216-217	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	32-78
32141499-1	2020	Fucosyltransferase 8 (FUT8) and beta-galactoside alpha-2,6-sialyltransferase 1 (ST6GAL1) are glycosyltransferases (GTases) that catalyze alpha1,6-fucosylation and alpha2,6-sialylation, respectively, in the mammalian N-glycosylation pathway.	Nitrogen	216-217	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	80-87
31931062-5	2020	The hemagglutination activity of rSHL1 was inhibited by N-linked glycoprotein transferrin.	Nitrogen	56-57	radial spoke head 6 homolog A	Rattus norvegicus	33-38
28892050-10	2018	In conclusion, the complex N-glycosylation of CEACAM6 is critical for EGFR signaling of OSCC invasion and metastasis.	Nitrogen	27-28	CEA cell adhesion molecule 6	Homo sapiens	46-53
31931062-8	2020	Finally, rSHL1 and rHEL1 were comparable in their ability to detect highly fucosylated N-glycans within glycoproteins on the surface of SW1116 human colorectal carcinoma cells.	Nitrogen	87-88	radial spoke head 6 homolog A	Rattus norvegicus	9-14
29295953-4	2018	The turnover of BiP was in part driven by its amino-terminal arginylation (Nt-arginylation) by the arginyltransferase ATE1, which generated an autophagic N-degron of the N-end rule pathway.	Nitrogen	75-76	arginyltransferase 1	Homo sapiens	118-122
31879129-2	2020	Although the Shank N-terminal domain and ankyrin repeats domain tandem (NTD-ANK) is known to bind to Ras and Rap1, the molecular mechanism underlying and functional significance of the bindings in synapses are unknown.	Nitrogen	19-20	ankyrin 1	Homo sapiens	76-79
31879888-7	2020	The N2 fixation rates annually range from 53.20 to 89.24 ngN L-1 h-1 for all of the sampling rivers, which is equivalent to a depth integrated (0-0.6 m) N input of 0.163-0.274 gN m-2 a-1.	Nitrogen	4-5	neogenin 1	Homo sapiens	57-60
29533934-10	2018	CONCLUSION: Our results show that the two N-glycosylation sites differentially influence stability and proteolytic processing of the IL-11R, but that N-linked glycosylation is not a prerequisite for IL-11 signaling.	Nitrogen	2-3	interleukin 11	Homo sapiens	133-138
31858211-10	2020	Dietary supplementation with a high n-6/n-3 ratio downregulated the protein expression of Cx45 and Panx1 in diabetic rats (p < 0.05-p < 0.01), while Cx43 immunoexpression was increased in diabetic rats fed with high and low n-6/n-3 ratios (p < 0.01-p < 0.001).	Nitrogen	16-17	Pannexin 1	Rattus norvegicus	99-104
31858211-10	2020	Dietary supplementation with a high n-6/n-3 ratio downregulated the protein expression of Cx45 and Panx1 in diabetic rats (p < 0.05-p < 0.01), while Cx43 immunoexpression was increased in diabetic rats fed with high and low n-6/n-3 ratios (p < 0.01-p < 0.001).	Nitrogen	22-23	Pannexin 1	Rattus norvegicus	99-104
29172509-4	2017	Ab initio computations of the three lowest lying intermolecular potential energy surfaces reveal two isomers, the hydrogen-bound (3Sigma) O-HCN complex and a nitrogen-bound (3Pi) HCN-O complex, lying 323 cm-1 higher in energy.	Nitrogen	158-166	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	179-182
31693237-5	2020	In previous cell-based assays, we found that certain N-terminally truncated PTH and PTHrP antagonist peptides function as inverse agonists and thus can reduce the high rates of basal cAMP signaling exhibited by the mutant PTHR1s of JMC in vitro.	Nitrogen	53-54	parathyroid hormone 1 receptor	Mus musculus	222-227
31962012-7	2020	Indeed, only one variant, in the conserved N-terminal zinc finger of GATA4, was considered pathogenic, with functional analysis confirming differences in its ability to regulate Sox9 and AMH and in protein interaction with ZFPM2.	Nitrogen	43-44	GATA binding protein 4	Homo sapiens	69-74
31962012-7	2020	Indeed, only one variant, in the conserved N-terminal zinc finger of GATA4, was considered pathogenic, with functional analysis confirming differences in its ability to regulate Sox9 and AMH and in protein interaction with ZFPM2.	Nitrogen	43-44	zinc finger protein, FOG family member 2	Homo sapiens	223-228
28888051-3	2017	Here we conducted an experiment to test how ant-plant-hemipteran interactions depend on nitrogen (N) availability by manipulating the presence of ants and aphids under different N fertilization treatments.	Nitrogen	88-96	solute carrier family 25 member 6	Homo sapiens	44-47
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	Nitrogen	38-39	alpha-L-iduronidase	Homo sapiens	218-222
32167360-2	2020	We follow this approach to identify, locate, and control two electron-nuclear spin defects in the environment of a single nitrogen-vacancy center in diamond.	Nitrogen	122-130	spindlin 1	Homo sapiens	78-82
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	Nitrogen	38-39	alpha-L-iduronidase	Homo sapiens	239-243
29209414-9	2017	Phosphorylation of RPS6, ATG13, and NNK1 proteins points toward a specific regulation of the TOR pathway under nitrogen deprivation.	Nitrogen	111-119	ribosomal protein S6	Chlamydomonas reinhardtii	19-23
32175496-9	2020	In contrast, HI-6 and 2-PAM showed higher affinities with more negative binding energy values and larger contribution of the amino acid Asp74, demonstrating the importance of the quaternary nitrogen to the affinity and interaction of oximes with AChE-GB and AChE-VX conjugates.	Nitrogen	190-198	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	24-27
31932304-6	2020	The results of these analyses indicated that Opi3 (as well as PEMT) has an N-out C-in topology and contains four transmembrane domains, with the fourth forming a re-entrant loop.	Nitrogen	75-76	bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase	Saccharomyces cerevisiae S288C	45-49
31931012-5	2020	In addition, a newly determined trimer structure, constituted by CCL5 and the E66S mutant, reported an interfacial interaction through the N-terminal 12FAY14 sequence.	Nitrogen	139-140	C-C motif chemokine ligand 5	Homo sapiens	65-69
28860277-1	2017	In metazoan organisms, the STT3A isoform of the oligosaccharyltransferase is localized adjacent to the protein translocation channel to catalyze co-translational N-linked glycosylation of proteins in the endoplasmic reticulum.	Nitrogen	162-163	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	27-32
31931012-9	2020	In contrast, the E66-R44/K45 interaction might dominate in CCL5 N-terminal truncations, and the interaction would lead to filament-like formation in solution.	Nitrogen	64-65	C-C motif chemokine ligand 5	Homo sapiens	59-63
31932307-4	2020	Through in ovo electroporation in embryonic chicken spinal cords, we demonstrate that the N-terminal Tinman (TN) domain and C-terminal (CT) domain synergistically promote OL differentiation by recruiting distinct transcriptional co-repressors, including enhancer of split Groucho 3 (GRG3), histone deacetylase 1 (HDAC1), and DNA methyltransferase 3 alpha (DNMT3A).	Nitrogen	90-91	DNA methyltransferase 3 alpha	Gallus gallus	325-354
31932307-4	2020	Through in ovo electroporation in embryonic chicken spinal cords, we demonstrate that the N-terminal Tinman (TN) domain and C-terminal (CT) domain synergistically promote OL differentiation by recruiting distinct transcriptional co-repressors, including enhancer of split Groucho 3 (GRG3), histone deacetylase 1 (HDAC1), and DNA methyltransferase 3 alpha (DNMT3A).	Nitrogen	90-91	DNA methyltransferase 3 alpha	Gallus gallus	356-362
32060313-3	2020	EndoBT-3987 is a key endo-beta-N-acetylglucosaminidase (ENGase) that initiates the degradation/processing of mammalian high-mannose-type (HM-type) N-glycans in the intestine.	Nitrogen	31-32	endo-beta-N-acetylglucosaminidase	Homo sapiens	56-62
31913636-4	2020	Iterative rounds of de-N-glycosylation followed by N-glycanation could be repeated at least 3 times, and was observed for other viral glycoproteins/vaccine antigens, including the envelope glycoprotein (Env) from HIV.	Nitrogen	23-24	endogenous retrovirus group K member 20	Homo sapiens	180-201
31913636-4	2020	Iterative rounds of de-N-glycosylation followed by N-glycanation could be repeated at least 3 times, and was observed for other viral glycoproteins/vaccine antigens, including the envelope glycoprotein (Env) from HIV.	Nitrogen	23-24	endogenous retrovirus group K member 20	Homo sapiens	203-206
31913636-4	2020	Iterative rounds of de-N-glycosylation followed by N-glycanation could be repeated at least 3 times, and was observed for other viral glycoproteins/vaccine antigens, including the envelope glycoprotein (Env) from HIV.	Nitrogen	51-52	endogenous retrovirus group K member 20	Homo sapiens	180-201
32025895-1	2020	Plant root associations with microbes such as mycorrhizal fungi or N-fixing bacteria enable ecosystems to tap pools of nitrogen (N) that might otherwise be inaccessible, including atmospheric N or N in large soil organic molecules.	Nitrogen	67-68	nuclear RNA export factor 1	Homo sapiens	106-109
32025895-1	2020	Plant root associations with microbes such as mycorrhizal fungi or N-fixing bacteria enable ecosystems to tap pools of nitrogen (N) that might otherwise be inaccessible, including atmospheric N or N in large soil organic molecules.	Nitrogen	119-127	nuclear RNA export factor 1	Homo sapiens	106-109
32025895-1	2020	Plant root associations with microbes such as mycorrhizal fungi or N-fixing bacteria enable ecosystems to tap pools of nitrogen (N) that might otherwise be inaccessible, including atmospheric N or N in large soil organic molecules.	Nitrogen	129-130	nuclear RNA export factor 1	Homo sapiens	106-109
32025895-1	2020	Plant root associations with microbes such as mycorrhizal fungi or N-fixing bacteria enable ecosystems to tap pools of nitrogen (N) that might otherwise be inaccessible, including atmospheric N or N in large soil organic molecules.	Nitrogen	129-130	nuclear RNA export factor 1	Homo sapiens	106-109
32025895-1	2020	Plant root associations with microbes such as mycorrhizal fungi or N-fixing bacteria enable ecosystems to tap pools of nitrogen (N) that might otherwise be inaccessible, including atmospheric N or N in large soil organic molecules.	Nitrogen	129-130	nuclear RNA export factor 1	Homo sapiens	106-109
32005391-2	2020	One of the first cloned RLKs is the Arabidopsis receptor kinase FLAGELLIN SENSING 2 (FLS2), which specifically recognizes a conserved 22 amino acid N-terminal sequence of Pseudomonas syringae pv.tomato DC3000 (Pst) flagellin protein (flg22).	Nitrogen	72-73	flagellin	Pseudomonas syringae pv. tomato str. DC3000	215-224
31917925-4	2020	We found that the main structural properties of TBP used to adapt to high temperature are: an increase in the ease of desolvation of charged residues at the surface, an increase in the local resiliency, the presence of Leu clusters in the protein core, and an increase in the loss of hydrophobic packing in the N-terminal subdomain.	Nitrogen	311-312	TATA-box binding protein	Homo sapiens	48-51
28860277-3	2017	Using genetically modified human cells that are deficient in DC2 or KCP2 proteins, we show that loss of DC2 causes a defect in co-translational N-glycosylation of proteins that mimics an STT3A-/- phenotype.	Nitrogen	144-145	keratinocyte associated protein 2	Homo sapiens	68-72
31937588-4	2020	We found that FIH1 modifies Asn35 within the uncharacterized N-terminal ubiquitin-associated (UBA)-like domain of Cezanne (UBACez), which lacks conserved UBA domain properties.	Nitrogen	61-62	hypoxia inducible factor 1 subunit alpha inhibitor	Homo sapiens	14-18
31944103-0	2020	ZIF-Derived Co9-xNixS8 Nanoparticles Immobilized on N-Doped Carbon as Efficient Catalyst for High-Performance Zinc-air Batteries.	Nitrogen	17-18	phosphoserine phosphatase pseudogene 1	Homo sapiens	12-15
31944103-2	2020	Here, the catalytic activity of a novel catalyst composed of Co9-xNixS8 nanoparticles immobilized on N-doped carbon (Co9-xNixS8/NC) is reported.	Nitrogen	66-67	phosphoserine phosphatase pseudogene 1	Homo sapiens	61-64
28860277-3	2017	Using genetically modified human cells that are deficient in DC2 or KCP2 proteins, we show that loss of DC2 causes a defect in co-translational N-glycosylation of proteins that mimics an STT3A-/- phenotype.	Nitrogen	144-145	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	187-192
31944103-2	2020	Here, the catalytic activity of a novel catalyst composed of Co9-xNixS8 nanoparticles immobilized on N-doped carbon (Co9-xNixS8/NC) is reported.	Nitrogen	66-67	phosphoserine phosphatase pseudogene 1	Homo sapiens	117-120
28883096-5	2017	We have generated a Drosophila COG7-CDG model that closely parallels the pathological characteristics of COG7-CDG patients, including pronounced neuromotor defects associated with altered N-glycome profiles.	Nitrogen	188-189	Component of oligomeric golgi complex 7	Drosophila melanogaster	31-35
32079099-4	2020	In addition, eqTHN N-glycosylation mutants colocalize obviously with ER, CD63, LAMP1 and endosomes, while WT eqTHN do not.	Nitrogen	17-18	CD63 molecule	Equus caballus	73-77
31843644-3	2020	SIRT7 contains a conserved catalytic core with long flanking N- and C-terminal extensions.	Nitrogen	61-62	sirtuin 7	Homo sapiens	0-5
28883096-5	2017	We have generated a Drosophila COG7-CDG model that closely parallels the pathological characteristics of COG7-CDG patients, including pronounced neuromotor defects associated with altered N-glycome profiles.	Nitrogen	188-189	Component of oligomeric golgi complex 7	Drosophila melanogaster	105-109
30023541-5	2017	In few cases, the N-alkyl derivatives showed increase of alpha-glucosidase inhibition and enhancement of antifungal activity compare to the respective parent iminosugar.	Nitrogen	18-19	sucrase-isomaltase	Homo sapiens	57-74
31801860-4	2020	We here identify the cellular Ubiquitin-specific-processing protease 7 (Usp7) as a new interaction partner of the MCPyV LT.Using GST pulldown experiments, we show that MCPyV LT directly binds to Usp7, and that N- as well as the C-terminal regions of LT bind to the TRAF (tumor necrosis factor receptor-associated) domain of Usp7.	Nitrogen	210-211	ubiquitin specific peptidase 7	Homo sapiens	72-76
31801860-4	2020	We here identify the cellular Ubiquitin-specific-processing protease 7 (Usp7) as a new interaction partner of the MCPyV LT.Using GST pulldown experiments, we show that MCPyV LT directly binds to Usp7, and that N- as well as the C-terminal regions of LT bind to the TRAF (tumor necrosis factor receptor-associated) domain of Usp7.	Nitrogen	210-211	ubiquitin specific peptidase 7	Homo sapiens	195-199
31801860-4	2020	We here identify the cellular Ubiquitin-specific-processing protease 7 (Usp7) as a new interaction partner of the MCPyV LT.Using GST pulldown experiments, we show that MCPyV LT directly binds to Usp7, and that N- as well as the C-terminal regions of LT bind to the TRAF (tumor necrosis factor receptor-associated) domain of Usp7.	Nitrogen	210-211	ubiquitin specific peptidase 7	Homo sapiens	195-199
31887030-2	2020	In this study, the IAPP21-27 segment was modified with a biotin linker at the N-terminus (Btn-GNNFGAIL) to immobilize peptide fibrils on streptavidin coated surfaces.	Nitrogen	78-79	butyrophilin subfamily 1 member A1	Homo sapiens	90-93
31730750-2	2020	Replacement of the N-terminal Aib residue of 1 with a DeltaAA afforded peptides 2a-c that maintained the 310-helical shape of 1.	Nitrogen	19-20	ANIB1	Homo sapiens	30-33
31800296-5	2020	Bioinformatics and 3D-structure prediction indicate that, like most HSPs, chicken GRP75 has two principal domains (the N-terminal ATPase and C-terminal region).	Nitrogen	119-120	heat shock protein family A (Hsp70) member 9	Gallus gallus	82-87
29079776-6	2017	We identify the kinase GCN2 as a sensor of the carbon/nitrogen precursor availability, whereas limitation of the sulfur precursor is transduced to TOR by downregulation of glucose metabolism.	Nitrogen	54-62	protein kinase family protein	Arabidopsis thaliana	23-27
31744379-6	2020	The resulting N-terminal Arg (Nt-Arg) binds the ZZ domain of SQSTM1, inducing oligomerization of SQSTM1-TRIM13 complexes and facilitating recruitment of LC3 on phagophores to the sites of reticulophagy.	Nitrogen	14-15	sequestosome 1	Homo sapiens	61-67
31744379-6	2020	The resulting N-terminal Arg (Nt-Arg) binds the ZZ domain of SQSTM1, inducing oligomerization of SQSTM1-TRIM13 complexes and facilitating recruitment of LC3 on phagophores to the sites of reticulophagy.	Nitrogen	14-15	sequestosome 1	Homo sapiens	97-103
31744379-6	2020	The resulting N-terminal Arg (Nt-Arg) binds the ZZ domain of SQSTM1, inducing oligomerization of SQSTM1-TRIM13 complexes and facilitating recruitment of LC3 on phagophores to the sites of reticulophagy.	Nitrogen	14-15	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	153-156
31879208-6	2020	The assay results showed the interesting relationship between the OX1R antagonistic activity and the substituents on the 17-nitrogen: the antagonistic activity was increased as the bulkiness of 17-substituents increased.	Nitrogen	124-132	hypocretin receptor 1	Homo sapiens	66-70
29079776-9	2017	In concert with GCN2, TOR allows photo-autotrophic eukaryotes to coordinate the fluxes of carbon, nitrogen, and sulfur for efficient cysteine biosynthesis under varying external nutrient supply.	Nitrogen	98-106	protein kinase family protein	Arabidopsis thaliana	16-20
28803208-0	2017	N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification.	Nitrogen	0-1	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	31-37
31658406-0	2020	N-terminal autoprocessing and acetylation of MARTX Makes-Caterpillars Floppy-like effector is stimulated by ADP-Ribosylation Factor 1 in advance of Golgi fragmentation.	Nitrogen	0-1	ADP ribosylation factor 1	Homo sapiens	108-133
28803208-0	2017	N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification.	Nitrogen	0-1	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	42-49
28803208-3	2017	However, the metabolic patterns of UGT1A4- and UGT2B10-mediated N-glucuronidation are not fully clear.	Nitrogen	64-65	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	35-41
31919192-8	2020	The N terminus of Ndc80, including a 27-residue sequence and Aurora B phosphorylation sites, is both necessary and sufficient for kinetochore protein degradation.	Nitrogen	4-5	kinetochore-associated Ndc80 complex subunit NDC80	Saccharomyces cerevisiae S288C	18-23
28803208-3	2017	However, the metabolic patterns of UGT1A4- and UGT2B10-mediated N-glucuronidation are not fully clear.	Nitrogen	64-65	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	47-54
28803208-4	2017	In this study, we first optimized in vitro reaction conditions for N-glucuronidation by using specific substrates (i.e., trifluoperazine for UGT1A4, cotinine and amitriptyline for UGT2B10).	Nitrogen	67-68	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	141-147
31276203-6	2020	Meanwhile, N-glycosylation of integrin alphavbeta3 and leukemia inhibitory factor receptor (LIFR) are found to play key roles in regulating the ECM-dependent FAK/Paxillin and LIF-induced STAT3 signaling pathways, respectively, thus affecting the receptive potentials of endometrial cells.	Nitrogen	11-12	integrin subunit alpha V	Homo sapiens	30-50
28803208-4	2017	In this study, we first optimized in vitro reaction conditions for N-glucuronidation by using specific substrates (i.e., trifluoperazine for UGT1A4, cotinine and amitriptyline for UGT2B10).	Nitrogen	67-68	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	180-187
30902024-8	2020	The catalytic efficiency (kcat/Km) for meperidine N-demethylation was similar between recombinant CYP2B6 and CYP2C19, but markedly lower by CYP3A4.	Nitrogen	50-51	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	109-116
28957628-1	2017	The first (N N)2- complex of a rare-earth metal with an end-on dinitrogen bridge, {K(crypt)}2{[(R2N)3Sc]2[mu-eta1:eta1-N2]} (crypt = 2.2.2-cryptand, R = SiMe3), has been isolated from the reduction of Sc(NR2)3 under dinitrogen at -35  C and characterized by X-ray crystallography.	Nitrogen	63-73	secreted phosphoprotein 1	Homo sapiens	109-113
31912881-4	2020	The N-terminal V-type Ig-domain of RAGE contains a triad of tryptophan residue; Trp51, Trp61 and Trp72.	Nitrogen	4-5	advanced glycosylation end-product specific receptor	Homo sapiens	35-39
28957628-1	2017	The first (N N)2- complex of a rare-earth metal with an end-on dinitrogen bridge, {K(crypt)}2{[(R2N)3Sc]2[mu-eta1:eta1-N2]} (crypt = 2.2.2-cryptand, R = SiMe3), has been isolated from the reduction of Sc(NR2)3 under dinitrogen at -35  C and characterized by X-ray crystallography.	Nitrogen	63-73	secreted phosphoprotein 1	Homo sapiens	114-118
28984135-1	2017	A novel enzyme-free electrochemical sensing strategy was proposed for sensitive monitoring of DNA and miRNA by smart combination of the cyclic cleavage reaction of Mg2+-dependent DNAzyme and the host-guest inclusion between ferrocene-labeled hairpin probe (H-1) and nitrogen-doped reduced graphene oxide/beta-cyclodextrin polymer (NRGO/beta-CDP) nanocomposites.	Nitrogen	266-274	H1.5 linker histone, cluster member	Homo sapiens	257-260
32072069-1	2020	c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are derived from three genes, Jnk1-3.	Nitrogen	6-7	mitogen activated protein kinase 10	Rattus norvegicus	132-138
29201936-5	2017	A synthetic chaperone consisting of the granzyme B ER signal peptide and a domain encompassing putative N-linked glycosylation sites in granzyme B is insufficient for payload transfer to target cells, whereas full-length granzyme B is sufficient for payload delivery.	Nitrogen	104-105	granzyme B	Homo sapiens	136-146
31998401-7	2020	Fatty acid synthesis in pigs from the H-BCAA group was lower than those from the N-BCAA group with the down-regulation of lipogenic genes (ACACA, FASN, PPAR-r, SREBP-1c in ventral and dorsal fat, SREBP-1c in liver) and up-regulation of lipolysis genes (HSL, ATGL, CPT-1A, FABP4 in ventral fat, HSL in liver) (P &lt; 0.05).	Nitrogen	81-82	sterol regulatory element binding transcription factor 1	Sus scrofa	160-168
31869201-7	2020	Interestingly, UVPD fragments also indicated that the charge at the "unfolding" N-terminus of ADH decreased at high in-source activation energies after the initial increase.	Nitrogen	80-81	aldo-keto reductase family 1 member A1	Homo sapiens	94-97
29201936-5	2017	A synthetic chaperone consisting of the granzyme B ER signal peptide and a domain encompassing putative N-linked glycosylation sites in granzyme B is insufficient for payload transfer to target cells, whereas full-length granzyme B is sufficient for payload delivery.	Nitrogen	104-105	granzyme B	Homo sapiens	136-146
31869201-8	2020	We proposed a possible "refolding-after-unfolding" mechanism, as further supported by monitoring hydrogen elimination from radical a-ions produced by UVPD at the N-terminus of ADH.	Nitrogen	162-163	aldo-keto reductase family 1 member A1	Homo sapiens	176-179
31870146-8	2020	We also propose a ligand induced conformational change bringing the N-termini of RAR and RXR closer together.	Nitrogen	68-69	retinoid X receptor alpha	Homo sapiens	89-92
32038686-8	2019	As interaction with PSY is mediated by the N-terminus of BoOR, which remains unaffected after splicing, all BoOR variants including BoOR-LD maintained interactions with PSY.	Nitrogen	43-44	PHYTOENE SYNTHASE	Arabidopsis thaliana	20-23
28733331-0	2017	N-Glycosylation is required for FDNC5 stabilization and irisin secretion.	Nitrogen	0-1	fibronectin type III domain containing 5	Homo sapiens	56-62
31937795-2	2020	The study objective was to assess the theoretical performance of artificial intelligence (AI)/machine learning (ML) algorithms to augment AKI recognition using the novel biomarker, neutrophil gelatinase associated lipocalin (NGAL), combined with contemporary biomarkers such as N-terminal pro B-type natriuretic peptide (NT-proBNP), urine output (UOP), and plasma creatinine.	Nitrogen	225-226	lipocalin 2	Homo sapiens	181-223
31754694-0	2020	Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin.	Nitrogen	25-26	TIMELESS interacting protein	Homo sapiens	86-91
31754723-6	2020	We show that the N-terminal 152 amino-acid residue segment of DHX30, denoted DHX30N, possesses all the antiviral activity of DHX30 and contains a dsRNA-binding domain, and that the NS1-DHX30 interaction in vivo requires the dsRNA-binding activity of both DHX30N and the NS1 RBD.	Nitrogen	17-18	influenza virus NS1A binding protein	Homo sapiens	270-273
31754723-7	2020	We demonstrate why this is the case using bacteria-expressed proteins: the DHX30N-NS1 RBD interaction in vitro requires the presence of a dsRNA platform that binds both NS1 RBD and DHX30N.	Nitrogen	80-81	influenza virus NS1A binding protein	Homo sapiens	82-85
31754723-7	2020	We demonstrate why this is the case using bacteria-expressed proteins: the DHX30N-NS1 RBD interaction in vitro requires the presence of a dsRNA platform that binds both NS1 RBD and DHX30N.	Nitrogen	80-81	influenza virus NS1A binding protein	Homo sapiens	169-172
31913260-6	2020	Collectively, our results show that N-glycosylated SGK196 plays suppression roles in BLBC metastases, therefore providing new insights into SGK196 function in BC.	Nitrogen	36-37	protein O-mannose kinase	Homo sapiens	51-57
31913260-6	2020	Collectively, our results show that N-glycosylated SGK196 plays suppression roles in BLBC metastases, therefore providing new insights into SGK196 function in BC.	Nitrogen	36-37	protein O-mannose kinase	Homo sapiens	140-146
31706164-4	2020	An impaired RIG-I-induced MAVS aggregation was observed in the presence of HBx-118N119E while MAVS-TRAF3 interaction was not affected.	Nitrogen	82-83	DExD/H-box helicase 58	Homo sapiens	12-17
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	ANIB1	Homo sapiens	206-209
31919301-4	2020	The molecules in the linear hexadepsipeptide amide in (S)-Pms-Acp-(S)-Pms-Acp-(S)-Pms-Acp-NMe2 acetonitrile solvate, C47H58N4O9 C2H3N, (3b), as well as in the related linear tetradepsipeptide amide (S)-Pms-Aib-(S)-Pms-Aib-NMe2, C28H37N3O6, (5a), the diastereoisomeric mixture (S,R)-Pms-Acp-(R,S)-Pms-Acp-NMe2/(R,S)-Pms-Acp-(R,S)-Pms-Acp-NMe2 (1:1), C32H41N3O6, (5b), and (R,S)-Mns-Acp-(S,R)-Mns-Acp-NMe2, C30H37N3O6, (5c) (Pms is phenyllactic acid, Acp is 1-aminocyclopentanecarboxylic acid and Mns is mandelic acid), generally adopt a beta-turn conformation in the solid state, which is stabilized by intramolecular N-H...O hydrogen bonds.	Nitrogen	90-91	ANIB1	Homo sapiens	218-221
32985231-6	2020	Microinjection of N-(1,3,4-Thiadiazolyl)nicotinamide-020 [TGN-020, a specific blocker of aquaporin 4] into the SON blocked MCAO-evoked increases in pERK1/2 in the SON as well as the reduction of GFAP and the increase in pERK1/2 and aquaporin 4 in the infarction area of the cortex.	Nitrogen	18-21	glial fibrillary acidic protein	Rattus norvegicus	195-199
32990603-3	2020	In protein- depleted states, N- and Met-deficiencies operate as limiting factors for LBM protein synthesis and accretion, causing growth retardation and subnormal TTR plasma values.	Nitrogen	29-30	transthyretin	Homo sapiens	163-166
32013488-3	2020	Here, we consider a star network, in which N identical peripheral end nodes are connected to the central hub node.	Nitrogen	43-44	ELAV like RNA binding protein 2	Homo sapiens	105-108
32013488-5	2020	As a proof of the concept, we examine the system of N double pendula (peripheral end nodes) located on the periodically oscillating platform (central hub).	Nitrogen	52-53	ELAV like RNA binding protein 2	Homo sapiens	150-153
31715212-3	2020	In this study, N-methylated peptide inhibitors F-N(Me)H-L, V-N(Me)F-R and R-N(Me)V-Y were synthesized against ACE, NEP and APN respectively, using their respective physiological substrates.	Nitrogen	15-16	membrane metallo-endopeptidase	Rattus norvegicus	115-118
31938070-2	2020	Methods: Here, we truncated 14-amino-acids at the N-terminus of MSI-78 to obtain MSI and further modified MSI to obtain four peptide analogs: MSI-1, MSI-2, MSI-3 and MSI-4.	Nitrogen	50-51	phenylalkylamine Ca2+ antagonist (emopamil) binding protein	Mus musculus	64-67
31882813-3	2019	In the present, we reported a novel neuroprotective manganese porphyrin reconstituted metal protein, Mn-TAT PTD-Ngb, consisting of a HIV Tat protein transduction domain sequence (TAT PTD) attached to the N-terminal of apo-Ngb.	Nitrogen	112-113	neuroglobin	Homo sapiens	222-225
31893224-9	2019	The motive of this research is to investigate the effect of highly electronegative N and -SO3 - (N-NGN) in comparison with the -OH, -COOH, and -SO3 - groups from a hydroxyl graphene and Nafion composite (N-OHGN) to mitigate PS shuttling in LSBs.	Nitrogen	204-210	neogenin 1	Homo sapiens	99-102
31891113-0	2019	The Arabidopsis thaliana N-recognin E3 ligase PROTEOLYSIS1 influences the immune response.	Nitrogen	25-26	proteolysis 1	Arabidopsis thaliana	46-58
31920515-3	2019	Recent crystal structures of sigma1R reveal a single N-terminal transmembrane segment and C-terminal ligand-binding domain, and a trimeric organization.	Nitrogen	53-54	sigma non-opioid intracellular receptor 1	Homo sapiens	29-36
31920515-10	2019	In contrast, N-terminally tagged sigma1R constructs show opposite trends to that of the intact construct, suggesting distorted elicitation of the ligand binding effects on oligomerization.	Nitrogen	13-14	sigma non-opioid intracellular receptor 1	Homo sapiens	33-40
31722427-5	2019	The N-terminal domain of NSUN5 is required for targeting to nucleoli, while two evolutionary highly conserved cysteines mediate catalysis.	Nitrogen	4-5	NOP2/Sun RNA methyltransferase 5	Homo sapiens	25-30
31834505-1	2019	A quantum chemical perspective of 31 structures contains electron acceptors: ASCl3 (arsenic trichloride), PCl3 (phosphorous trichloride) and NCl3 (nitrogen trichloride); forming non-covalent bond with various nitrogen-based electron donors that resulted in pnicogen bonds, AS...N, P...N and N...N were calculated at M062X/def2-QZVP level of theory.	Nitrogen	147-155	calpain 5	Homo sapiens	141-145
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	Nef	Human immunodeficiency virus 1	30-33
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	Nef	Human immunodeficiency virus 1	90-93
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	Nef	Human immunodeficiency virus 1	90-93
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	Nef	Human immunodeficiency virus 1	90-93
31597760-2	2019	An N-terminal region in HIV-1 Nef encompassing residues 12-39 has been implicated in many Nef activities including disruption of CD4 T lymphocyte polarization and homing to lymph nodes, antagonism of SERINC5 restriction to virion infectivity, downregulation of cell surface CD4 and MHC-I, release of Nef-containing extracellular vesicles, and phosphorylation of Nef by recruitment of the Nef-associated kinase complex (NAKC).	Nitrogen	3-4	Nef	Human immunodeficiency virus 1	90-93
31597760-8	2019	These results identify the N-terminal region as a multi-functional interaction module for at least three different host cell ligands that mediate independent functions of HIV-1SF2Nef to facilitate immune evasion and virus spread.IMPORTANCE HIV-1 Nef critically determines virus spread and disease progression in infected individuals by acting as protein-interaction adaptor via incompletely defined mechanisms and ligands.	Nitrogen	27-28	Nef	Human immunodeficiency virus 1	179-182
31597760-9	2019	Residues 12-39 near the N-terminus of Nef have been described as interaction platform for the Nef-associated kinase complex (NAKC) and were recently identified as essential determinants for a broad range of Nef activities.	Nitrogen	24-25	Nef	Human immunodeficiency virus 1	94-97
31825828-4	2019	Disruption of K-RAS cluster formation requires the N terminus of DIRAS3 and interaction of both DIRAS3 and K-RAS with the plasma membrane.	Nitrogen	51-52	KRAS proto-oncogene, GTPase	Homo sapiens	14-19
31825828-4	2019	Disruption of K-RAS cluster formation requires the N terminus of DIRAS3 and interaction of both DIRAS3 and K-RAS with the plasma membrane.	Nitrogen	51-52	DIRAS family GTPase 3	Homo sapiens	65-71
31822618-3	2019	The telomerase interaction surface on human TPP1 has been mapped to 2 regions of the N-terminal oligosaccharide/oligonucleotide-binding (OB) domain, namely the TPP1 glutamate (E) and leucine (L)-rich (TEL) patch and the N terminus of TPP1-oligosaccharide/oligonucleotide-binding (NOB) region.	Nitrogen	85-86	tripeptidyl peptidase 1	Homo sapiens	44-48
31822618-3	2019	The telomerase interaction surface on human TPP1 has been mapped to 2 regions of the N-terminal oligosaccharide/oligonucleotide-binding (OB) domain, namely the TPP1 glutamate (E) and leucine (L)-rich (TEL) patch and the N terminus of TPP1-oligosaccharide/oligonucleotide-binding (NOB) region.	Nitrogen	85-86	tripeptidyl peptidase 1	Homo sapiens	160-164
31822618-3	2019	The telomerase interaction surface on human TPP1 has been mapped to 2 regions of the N-terminal oligosaccharide/oligonucleotide-binding (OB) domain, namely the TPP1 glutamate (E) and leucine (L)-rich (TEL) patch and the N terminus of TPP1-oligosaccharide/oligonucleotide-binding (NOB) region.	Nitrogen	85-86	tripeptidyl peptidase 1	Homo sapiens	160-164
31822618-3	2019	The telomerase interaction surface on human TPP1 has been mapped to 2 regions of the N-terminal oligosaccharide/oligonucleotide-binding (OB) domain, namely the TPP1 glutamate (E) and leucine (L)-rich (TEL) patch and the N terminus of TPP1-oligosaccharide/oligonucleotide-binding (NOB) region.	Nitrogen	220-221	tripeptidyl peptidase 1	Homo sapiens	44-48
31563738-2	2019	Then the experimental results showed that the IA1 mode (4 h aeration and 1 h non-aeration) could improve the simultaneous nitrogen and phosphorus removal and the settleability of granules in continuous flow system.	Nitrogen	122-130	INSM transcriptional repressor 1	Homo sapiens	46-49
31239195-1	2019	Flavin-containing monooxygenase (FMO) 3 together with cytochrome P450 (CYP) 2C19 play a significant role in voriconazole N-oxidation.	Nitrogen	121-122	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	0-39
31239195-1	2019	Flavin-containing monooxygenase (FMO) 3 together with cytochrome P450 (CYP) 2C19 play a significant role in voriconazole N-oxidation.	Nitrogen	121-122	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	54-80
31550533-2	2019	Driven by an N-terminal alpha/beta-hydrolase-folded domain with a protruding interaction helix, EDS1 assembles with two homologs, phytoalexin-deficient 4 (PAD4) and senescence-associated gene 101 (SAG101).	Nitrogen	13-14	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	96-100
31550533-2	2019	Driven by an N-terminal alpha/beta-hydrolase-folded domain with a protruding interaction helix, EDS1 assembles with two homologs, phytoalexin-deficient 4 (PAD4) and senescence-associated gene 101 (SAG101).	Nitrogen	13-14	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	130-153
32042831-6	2019	Results suggested that deleterious variants were mostly enriched in the N- and C-terminal domain of the BRCA1 and BRCA2 C-terminus.	Nitrogen	72-73	BRCA1 DNA repair associated	Homo sapiens	104-109
32042831-6	2019	Results suggested that deleterious variants were mostly enriched in the N- and C-terminal domain of the BRCA1 and BRCA2 C-terminus.	Nitrogen	72-73	BRCA2 DNA repair associated	Homo sapiens	114-119
32029032-1	2019	OBJECTIVE: To investigate whether endogenous nociceptin/orphanin FQ (N/OFQ) can inhibit arrhythmia and expression of beta1-adrenergic receptor (beta1-AR) on the surface of myocardial cell membrane in acute myocardial ischemia rats by Raf kinase inhibitory protein (RKIP).	Nitrogen	69-70	phosphatidylethanolamine binding protein 1	Rattus norvegicus	234-263
32029032-1	2019	OBJECTIVE: To investigate whether endogenous nociceptin/orphanin FQ (N/OFQ) can inhibit arrhythmia and expression of beta1-adrenergic receptor (beta1-AR) on the surface of myocardial cell membrane in acute myocardial ischemia rats by Raf kinase inhibitory protein (RKIP).	Nitrogen	69-70	phosphatidylethanolamine binding protein 1	Rattus norvegicus	265-269
31751425-5	2019	The facts that phosphorylation of Ser-1072 in FMNL2 has been shown to play a critical role in integrin beta1 internalization mediated by FMNL2 and that Ser-171 in FMNL2 and Ser-174 in FMNL3 are novel putative phosphorylation sites conserved between FMNL2 and FMNL3 indicate that the strategy used in this study is a useful tool for identifying and characterizing physiologically important phosphorylation reactions occurring on N-myristoylated proteins.	Nitrogen	48-49	integrin subunit beta 1	Homo sapiens	94-108
31545178-5	2019	Microaerophilic treatment of RTE by enriched bacterial community DR4, in the presence of optimized electron donor (sucrose) and nitrogen source (yeast extract) resulted in 88% of American Dye Manufacturer"s Institute (ADMI) removal and 98% of Chemical oxygen demand (COD) reduction within 32 h at 37  C. In silico prediction of the functional genes within bacterial community DR4 was made by Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt) analysis.	Nitrogen	128-136	major histocompatibility complex, class II, DR beta 4	Homo sapiens	65-68
31511384-14	2019	The two specific thioredoxin subunits of STT3B-OST MAGT1 and TUSC3 were found to be essential for the N-glycosylation of viral GP.	Nitrogen	102-103	magnesium transporter 1	Homo sapiens	51-56
31558607-0	2019	N-Glycosylation is required for secretion of the precursor to brain-derived neurotrophic factor (proBDNF) carrying sulfated LacdiNAc structures.	Nitrogen	0-1	brain derived neurotrophic factor	Homo sapiens	62-95
30835861-2	2019	The neonatal presentation of bi-allelic mutations of CPS1 results in hyperammonemia with reduced citrulline and is reported as the most challenging nitrogen metabolism disorder to treat.	Nitrogen	148-156	carbamoyl-phosphate synthetase 1	Mus musculus	53-57
31742248-4	2019	Through the production of an N-terminal polypeptide of HDAC4 (HDAC4-NT), ABHD5 inhibits MEF2-dependent gene expression and thereby controls glucose handling.	Nitrogen	29-30	abhydrolase domain containing 5	Mus musculus	73-78
31279203-6	2019	The MER was able to remove 89.1 +- 2.9% of total nitrogen from the leachate while recovering about 51% of the influent ammonia in the catholyte, in comparison to 38.1 +- 4.4% of total nitrogen removal by the control reactor.	Nitrogen	49-57	G protein-coupled estrogen receptor 1	Homo sapiens	4-7
31279203-6	2019	The MER was able to remove 89.1 +- 2.9% of total nitrogen from the leachate while recovering about 51% of the influent ammonia in the catholyte, in comparison to 38.1 +- 4.4% of total nitrogen removal by the control reactor.	Nitrogen	184-192	G protein-coupled estrogen receptor 1	Homo sapiens	4-7
31593206-0	2019	A di-boron pair doped MoS2 (B2@MoS2) single-layer shows superior catalytic performance for electrochemical nitrogen activation and reduction.	Nitrogen	107-115	immunoglobulin kappa variable 5-2	Homo sapiens	28-35
31593206-3	2019	Herein from DFT simulations, we report diatomic boron doped single-layer MoS2, B2@MoS2, as the potential electrocatalyst for the nitrogen reduction reaction, and compare it with single boron atom doped MoS2, B@MoS2, based on thermodynamics, selectivity, and kinetics analysis.	Nitrogen	129-137	immunoglobulin kappa variable 5-2	Homo sapiens	79-86
31593206-5	2019	Furthermore, the B2@MoS2 catalyst can effectively activate the inert N2 and promote N2 reduction to NH3 via the enzymatic mechanism, and shows much better electrocatalytic activity than B@MoS2, as reflected by the significantly reduced overpotential (0.02 V vs. 0.30 V) and the much lower activation barrier (1.24 eV vs. 2.84 eV).	Nitrogen	69-71	immunoglobulin kappa variable 5-2	Homo sapiens	17-24
31833223-5	2020	The lack of the Armi N-terminus also blocks the Piwi-pre-piRISC exit from Yb bodies.	Nitrogen	21-22	piwi like RNA-mediated gene silencing 1	Homo sapiens	48-52
31934692-2	2020	The enantioselectivities of the corresponding products with the same catalyst could be switched by using different N-protecting groups (N-PMP or N-Boc).	Nitrogen	115-116	BOC cell adhesion associated, oncogene regulated	Homo sapiens	147-150
32019936-2	2020	The eukaryotic replicative CMG (Cdc45, Mcm2-7, GINS) helicase contains a Mcm2-7 motor ring, with the N-tier ring in front and the C-tier motor ring behind.	Nitrogen	49-50	minichromosome maintenance complex component 2	Homo sapiens	73-79
31858729-6	2020	The decrease in prolargin post-HT correlated with improved mean right atrial pressure (rs = 0.63; P = 0.00091), stroke volume index (rs = -0.73; P &lt; 0.0001), cardiac index (rs = -0.64; P = 0.00057), left ventricular stroke work index (rs = -0.49; P = 0.015), and N-terminal pro brain natriuretic peptide (rs = 0.7; P &lt; 0.0001).	Nitrogen	266-267	proline and arginine rich end leucine rich repeat protein	Homo sapiens	16-25
31702436-5	2020	By expressing the N-terminal PAD4 lipase-like domain (PAD4LLD) without its C-terminal "EDS1-PAD4" (EP) domain, we interrogated PAD4 functions in plant defense.	Nitrogen	18-19	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	29-33
31702436-5	2020	By expressing the N-terminal PAD4 lipase-like domain (PAD4LLD) without its C-terminal "EDS1-PAD4" (EP) domain, we interrogated PAD4 functions in plant defense.	Nitrogen	18-19	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	54-58
31702436-5	2020	By expressing the N-terminal PAD4 lipase-like domain (PAD4LLD) without its C-terminal "EDS1-PAD4" (EP) domain, we interrogated PAD4 functions in plant defense.	Nitrogen	18-19	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	54-58
31974610-7	2020	HDAC9 expression level in tumor tissues was negatively associated with tumor size (P=0.026), T stage (P=0.014) and N stage (P=0.004).	Nitrogen	115-116	histone deacetylase 9	Homo sapiens	0-5
30902024-14	2020	These findings demonstrate that the relative CYP3A4, CYP2B6, and CYP2C19 involvement in meperidine N-demethylation depends on the enzyme activities in individual human liver microsomal samples.	Nitrogen	99-100	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	65-72
31978062-8	2020	Our findings suggest that, potentially due to overall variation in N-glycosylation across variants, nuanced differences in binding of TF Env to DC-SIGN might trigger alternative DC immune responses (IRs) in the female genital tract (FGT) that favour HIV-1 survival and facilitate transmission.	Nitrogen	67-68	endogenous retrovirus group K member 20	Homo sapiens	137-140
31913609-1	2020	Herein, we report the synthesis and characterization of the mixed-valent, ketimide-stabilized Pd7 nanosheet, [Pd7(N CtBu2)6] (1), via reaction of PdCl2(PhCN)2 and Li(N CtBu2).	Nitrogen	114-115	phosducin like 2	Homo sapiens	146-158
31819009-5	2020	To create a longer-lasting alternative, PASylated IL-1Ra (PAS-IL-1Ra) has been generated by in-frame fusion of a long, defined-length, N-terminal Pro-Ala-Ser (PAS) random coil polypeptide with IL-1Ra.	Nitrogen	135-136	interleukin 1 receptor antagonist	Mus musculus	50-56
31754010-7	2020	Importantly the actin-binding N-terminal LIM domain and nebulin repeats of LASP2 are required for spine stability and dendritic arbor complexity.	Nitrogen	30-31	nebulette	Rattus norvegicus	75-80
31941025-3	2020	cJun N-terminal kinase (JNK), a member of the MAPK family, plays a central role in HCC pathogenesis.	Nitrogen	5-6	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	0-4
31913260-0	2020	N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells.	Nitrogen	0-1	protein O-mannose kinase	Homo sapiens	15-21
31913260-3	2020	In the current study, we demonstrated that SGK196 is primarily modified by N-glycosylation in breast cancer (BC) cells.	Nitrogen	75-76	protein O-mannose kinase	Homo sapiens	43-49
31913260-4	2020	Furthermore, gain and loss-of-function studies showed that N-glycosylated SGK196 suppresses cell migration, invasion, and metastasis in BC, particularly in the basal-like breast cancer (BLBC) type.	Nitrogen	59-60	protein O-mannose kinase	Homo sapiens	74-80
31913260-5	2020	In addition, we found that SGK196 N-glycosylation performs the regulatory function through the PI3K/AKT/GSK3beta signaling pathway.	Nitrogen	34-35	protein O-mannose kinase	Homo sapiens	27-33
31936183-9	2020	In conclusion, rs1800872 in IL10 was the only associated with N-ERD in Mexican-mestizo patients.	Nitrogen	62-63	interleukin 10	Homo sapiens	28-32
31666375-4	2020	Here, we report that vIRF-2 also targets USP7, utilizing a PSTS motif matching the USP7 N-terminal domain-binding A/PxxS consensus, but uniquely requires catalytic-domain residues for intracellular interaction.	Nitrogen	88-89	ubiquitin specific peptidase 7	Homo sapiens	41-45
31935810-2	2020	Herein, the synthesis of a macromolecular spirocyclic phosphorus/nitrogen-containing IFR poly sulfonamide spirocyclic pentaerythritol bisphosphonate (SAPC) is reported via a two-step method that uses pentaerythritol, phosphorus oxychloride and sulfonamide (SAA) as raw materials.	Nitrogen	65-73	serum amyloid A1 cluster	Homo sapiens	257-260
31587482-5	2020	Activation of extracellular signal-regulated protein kinase (ERK) and c-jun N-terminal kinase was observed in bladder cancer after BITC treatment for 24 hours.	Nitrogen	76-77	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	70-75
31739063-5	2020	Furthermore, biological pathways analysis demonstrated that histidine metabolism, nitrogen metabolism, tryptophan and part glycerophospholipids metabolism were notably modified by PSG treatment in ALI rats.	Nitrogen	82-90	pregnancy-specific beta 1-glycoprotein	Rattus norvegicus	180-183
31631405-6	2020	GST pull down and yeast two-hybrid assay showed that the interactive smallest fragments were on the 319-379 position of Runx2 and the N-terminus 110-amino acid DBD of the VDR.	Nitrogen	134-135	vitamin D (1,25-dihydroxyvitamin D3) receptor	Mus musculus	171-174
32054416-0	2020	A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitope.	Nitrogen	124-125	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	62-105
32167012-10	2020	The results of our study provide new insight into N-glycosylation-based interaction of the mAb:CD16a complex.	Nitrogen	50-51	Fc gamma receptor IIIa	Homo sapiens	95-100
31541450-5	2020	The amino acid sequence of the peptide was taken from the site around the phosphorylation site near the N-terminal region of the maize C4-isoform of PEPC.	Nitrogen	104-105	phosphoenolpyruvate carboxylase 1	Zea mays	149-153
31770454-0	2020	Deletion of the N-terminal domain of the yeast vacuolar (Na+ ,K+ )/H+ antiporter Vnx1p improves salt tolerance in yeast and transgenic Arabidopsis.	Nitrogen	16-17	Vnx1p	Saccharomyces cerevisiae S288C	81-86
31770454-4	2020	In this study we have identified an autoinhibitory N-terminal domain, and have engineered a constitutively activated version of Vnx1p, by removing this domain.	Nitrogen	51-52	Vnx1p	Saccharomyces cerevisiae S288C	128-133
31905841-7	2019	siTNS3 treatment upregulated p16 and p21 levels and downregulated SOX2 expression and focal adhesion kinase, protein kinase B, and c-Jun N-terminal kinase phosphorylation.	Nitrogen	3-4	SRY-box transcription factor 2	Homo sapiens	66-70
31714482-9	2019	In addition, N15 treatment markedly increased the newly mature neurons and enhanced the expression levels of growth-associated protein-43, synaptophysin, brain-derived neurotrophic factor and neurotrophin-3 in the hippocampus.	Nitrogen	13-16	brain-derived neurotrophic factor	Rattus norvegicus	154-187
31714482-10	2019	Moreover, N15 promoted the activation of PPARalpha and PPARgamma on day 7 and 14 after cerebral ischaemia.	Nitrogen	10-13	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	55-64
31610913-4	2019	One of the TRPM2 splicing variants, short TRPM2 (TRPM2-S) having only the N-terminus and first two transmembrane domains, was reported to prevent full-length TRPM2 (TRPM2-L) activation.	Nitrogen	74-75	transient receptor potential cation channel subfamily M member 2	Homo sapiens	11-16
31610913-4	2019	One of the TRPM2 splicing variants, short TRPM2 (TRPM2-S) having only the N-terminus and first two transmembrane domains, was reported to prevent full-length TRPM2 (TRPM2-L) activation.	Nitrogen	74-75	transient receptor potential cation channel subfamily M member 2	Homo sapiens	42-47
31610913-4	2019	One of the TRPM2 splicing variants, short TRPM2 (TRPM2-S) having only the N-terminus and first two transmembrane domains, was reported to prevent full-length TRPM2 (TRPM2-L) activation.	Nitrogen	74-75	transient receptor potential cation channel subfamily M member 2	Homo sapiens	42-47
31610913-4	2019	One of the TRPM2 splicing variants, short TRPM2 (TRPM2-S) having only the N-terminus and first two transmembrane domains, was reported to prevent full-length TRPM2 (TRPM2-L) activation.	Nitrogen	74-75	transient receptor potential cation channel subfamily M member 2	Homo sapiens	42-47
31610913-4	2019	One of the TRPM2 splicing variants, short TRPM2 (TRPM2-S) having only the N-terminus and first two transmembrane domains, was reported to prevent full-length TRPM2 (TRPM2-L) activation.	Nitrogen	74-75	transient receptor potential cation channel subfamily M member 2	Homo sapiens	165-172
31929866-9	2019	The serum levels and relative expressions of SDF-1 and CXCR4 were positively correlated with blood urea nitrogen, parathyroid hormone, and high-sensitivity C-reactive protein and inversely correlated with hemoglobin.	Nitrogen	104-112	C-X-C motif chemokine receptor 4	Homo sapiens	55-60
31710471-6	2019	Cells lacking Cap2p showed altered localization of Msb2p and increased shedding of Msb2p"s N-terminal glycosylated domain.	Nitrogen	91-92	Msb2p	Saccharomyces cerevisiae S288C	83-88
31589250-10	2019	In multivariable-adjusted analyses, fish oil supplementation and fatty cold water fish intake were positively associated with DHA and the "high n-3 PUFA" pattern.	Nitrogen	1-2	pumilio RNA binding family member 3	Homo sapiens	148-152
31189070-11	2019	Using CFBE41o cells, we showed that the positive SLC6A14 effect was mainly dependent on the nitric oxide (NO) synthase activity, nitrogen oxides, including NO, and phosphorylation by protein kinase G. These finding were confirmed in CF-HBE, as inducible NO synthase inhibition abrogated the functional interaction between SLC6A14 and pharmacological corrected F508del-CFTR.	Nitrogen	129-137	solute carrier family 6 member 14	Homo sapiens	49-56
31655312-8	2019	In addition, TRPM2 knockout markedly improved renal dysfunction, as evidenced by the reduced serum creatine, blood urea nitrogen (BUN), kidney injury molecule 1 (KIM-1) expression and enhanced Nephrin levels.	Nitrogen	120-128	transient receptor potential cation channel, subfamily M, member 2	Mus musculus	13-18
31741272-2	2019	The product of the Arabidopsis thaliana gene AtAAP1 substantially contributes to inorganic nitrogen acquisition under ecologically relevant amino acid concentrations.	Nitrogen	91-99	amino acid permease 1	Arabidopsis thaliana	45-51
31638225-11	2019	Function enrichment analysis revealed the genes in the ceRNA network that participated in the p53 signaling pathway [cyclin E2 (CCNE2), ribonucleotide reductase M2 subunit (RRM2)] and nitrogen metabolism [carbonic anhydrase 2 (CA2)], which were also included in the pathways of the CTD.	Nitrogen	184-192	carbonic anhydrase 2	Homo sapiens	205-225
31638225-11	2019	Function enrichment analysis revealed the genes in the ceRNA network that participated in the p53 signaling pathway [cyclin E2 (CCNE2), ribonucleotide reductase M2 subunit (RRM2)] and nitrogen metabolism [carbonic anhydrase 2 (CA2)], which were also included in the pathways of the CTD.	Nitrogen	184-192	carbonic anhydrase 2	Homo sapiens	227-230
31681931-4	2019	In addition, owing to the reduction of the band gap, decoration with B can greatly enhance the visible light and infrared light harvesting of BlP and BeP, guaranteeing them as ideal potential materials for the visible light reduction of N2.	Nitrogen	237-239	dynein light chain roadblock-type 1	Homo sapiens	142-145
31681931-6	2019	The oxidation of the BlP and BeP surfaces can also enhance the N2 reduction reaction (NRR) performances using visible light driving, with the etaNRR values being 1.31 and 1.51 V through the end-on and side-on configurations, respectively.	Nitrogen	63-65	dynein light chain roadblock-type 1	Homo sapiens	21-24
31828042-4	2019	Exploratory in silico analysis aided by phospho-substrate antibodies and ZEB1 deletion mutants led us to identify several potential phospho-sites for the family of PKC kinases in the N-terminus of ZEB1.	Nitrogen	183-184	zinc finger E-box binding homeobox 1	Homo sapiens	73-77
31828042-4	2019	Exploratory in silico analysis aided by phospho-substrate antibodies and ZEB1 deletion mutants led us to identify several potential phospho-sites for the family of PKC kinases in the N-terminus of ZEB1.	Nitrogen	183-184	zinc finger E-box binding homeobox 1	Homo sapiens	197-201
31734536-6	2019	Mutagenesis studies suggest an indispensable role for N-terminal domain of SCGN in modulating insulin stability and function.	Nitrogen	54-55	secretagogin, EF-hand calcium binding protein	Mus musculus	75-79
31593206-5	2019	Furthermore, the B2@MoS2 catalyst can effectively activate the inert N2 and promote N2 reduction to NH3 via the enzymatic mechanism, and shows much better electrocatalytic activity than B@MoS2, as reflected by the significantly reduced overpotential (0.02 V vs. 0.30 V) and the much lower activation barrier (1.24 eV vs. 2.84 eV).	Nitrogen	84-86	immunoglobulin kappa variable 5-2	Homo sapiens	17-24
31320601-2	2019	Herein, we designed the novel p-n heterojunction photocatalyst TiO2/SnO microflower (TiO2/F-SnO) with hierarchical architecture by decorating TiO2 nanoparticles on the surface of the SnO microflower via a simple hydrothermal route.	Nitrogen	5-6	strawberry notch homolog 2	Homo sapiens	68-71
31320601-2	2019	Herein, we designed the novel p-n heterojunction photocatalyst TiO2/SnO microflower (TiO2/F-SnO) with hierarchical architecture by decorating TiO2 nanoparticles on the surface of the SnO microflower via a simple hydrothermal route.	Nitrogen	5-6	strawberry notch homolog 2	Homo sapiens	92-95
31320601-2	2019	Herein, we designed the novel p-n heterojunction photocatalyst TiO2/SnO microflower (TiO2/F-SnO) with hierarchical architecture by decorating TiO2 nanoparticles on the surface of the SnO microflower via a simple hydrothermal route.	Nitrogen	5-6	strawberry notch homolog 2	Homo sapiens	92-95
31649274-0	2019	Structural Dynamics of the N-Extension of Cardiac Troponin I Complexed with Troponin C by Site-Directed Spin Labeling Electron Paramagnetic Resonance.	Nitrogen	27-28	troponin I3, cardiac type	Homo sapiens	42-60
31649274-0	2019	Structural Dynamics of the N-Extension of Cardiac Troponin I Complexed with Troponin C by Site-Directed Spin Labeling Electron Paramagnetic Resonance.	Nitrogen	27-28	spindlin 1	Homo sapiens	104-108
31649274-1	2019	The secondary structure of the N-extension of cardiac troponin I (cTnI) was determined by measuring the distance distribution between spin labels attached to the i and i + 4 residues: 15/19, 23/27, 27/31, 35/39, and 43/47.	Nitrogen	31-32	troponin I3, cardiac type	Homo sapiens	46-64
31649274-1	2019	The secondary structure of the N-extension of cardiac troponin I (cTnI) was determined by measuring the distance distribution between spin labels attached to the i and i + 4 residues: 15/19, 23/27, 27/31, 35/39, and 43/47.	Nitrogen	31-32	troponin I3, cardiac type	Homo sapiens	66-70
31649274-1	2019	The secondary structure of the N-extension of cardiac troponin I (cTnI) was determined by measuring the distance distribution between spin labels attached to the i and i + 4 residues: 15/19, 23/27, 27/31, 35/39, and 43/47.	Nitrogen	31-32	spindlin 1	Homo sapiens	134-138
31844685-7	2019	Interestingly, the disordered C- and N- terminal regions of GEMININ were involved in binding to SIX3/SIX6.	Nitrogen	37-38	SIX homeobox 6	Homo sapiens	101-105
31648314-0	2019	Targeting chronic lymphocytic leukemia with N-methylated thrombospondin-1-derived peptides overcomes drug resistance.	Nitrogen	44-45	thrombospondin 1	Mus musculus	57-73
31648314-3	2019	Here, we demonstrate that the use of N-methylated thrombospondin-1 (TSP-1)-derived peptides is an efficient way to kill the malignant CLL cells, including those from high-risk individuals with poor clinical prognosis, del11q, del17p, 2p gain, or complex karyotype.	Nitrogen	37-38	thrombospondin 1	Mus musculus	50-66
31648314-3	2019	Here, we demonstrate that the use of N-methylated thrombospondin-1 (TSP-1)-derived peptides is an efficient way to kill the malignant CLL cells, including those from high-risk individuals with poor clinical prognosis, del11q, del17p, 2p gain, or complex karyotype.	Nitrogen	37-38	thrombospondin 1	Mus musculus	68-73
31610800-1	2019	BACKGROUND: The ST6Gal-I glycosyltransferase, which adds alpha2-6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer.	Nitrogen	8-9	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	16-24
31610800-1	2019	BACKGROUND: The ST6Gal-I glycosyltransferase, which adds alpha2-6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer.	Nitrogen	8-9	immunoglobulin binding protein 1	Homo sapiens	57-65
31532667-0	2019	One-Step Facile Synthesis of Nitrogen-Doped Carbon Dots: A Ratiometric Fluorescent Probe for Evaluation of Acetylcholinesterase Activity and Detection of Organophosphorus Pesticides in Tap Water and Food.	Nitrogen	29-37	nuclear RNA export factor 1	Homo sapiens	185-188
31532667-2	2019	In this study, a highly selective and sensitive ratiometric fluorescent probe was innovatively fabricated for the evaluation of AChE activity and the determination of OPs in tap water and food on the basis of the inner filter effect (IFE) between nitrogen-doped carbon dots (N-CDs) and 2,3-diaminophenazine (DAP).	Nitrogen	247-255	nuclear RNA export factor 1	Homo sapiens	174-177
31637240-11	2019	Our study demonstrated direct binding of IFT complex B proteins IFT52 and IFT57 to the N-terminal ankyrin repeats and the central domain of SANS.	Nitrogen	87-88	intraflagellar transport 52	Homo sapiens	64-69
31600047-6	2019	Because a-synuclein is N-terminally acetylated in vivo, we established that Atox1 also inhibits amyloid formation of this variant in vitro, and proximity ligation in human cell lines demonstrated a-synuclein-Atox1 interactions in situ.	Nitrogen	23-24	antioxidant 1 copper chaperone	Homo sapiens	76-81
31591270-0	2019	Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate.	Nitrogen	19-20	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	Homo sapiens	109-114
31591270-5	2019	Here, we investigated whether PIP2 controls binding of the N-terminal extension of ARF1 to ASAP1"s PH domain and thereby regulates its GAP activity.	Nitrogen	59-60	ADP ribosylation factor 1	Homo sapiens	83-87
28733331-2	2017	Biochemical data have shown that N-glycosylation of FNDC5 is unlikely to affect ligand or receptor activation of irisin.	Nitrogen	33-34	fibronectin type III domain containing 5	Homo sapiens	52-57
31591270-8	2019	A peptide comprising residues 2-17 of ARF1 ([2-17]ARF1) inhibited GAP activity and PIP2-dependently bound to a protein containing the PH domain and a 17-amino-acid-long interdomain linker immediately N-terminal to the first beta-strand of the PH domain.	Nitrogen	200-201	ADP ribosylation factor 1	Homo sapiens	38-42
31371405-4	2019	Furthermore, we found that DDR-2 is N-glycosylated at the Asp-141 residue located in its discoidin domain, and mutation of this residue caused an axon regeneration defect.	Nitrogen	36-37	Discoidin domain-containing receptor tyrosine kinase B	Caenorhabditis elegans	27-32
31591270-8	2019	A peptide comprising residues 2-17 of ARF1 ([2-17]ARF1) inhibited GAP activity and PIP2-dependently bound to a protein containing the PH domain and a 17-amino-acid-long interdomain linker immediately N-terminal to the first beta-strand of the PH domain.	Nitrogen	200-201	ADP ribosylation factor 1	Homo sapiens	50-54
28733331-3	2017	The N-glycosylation of FNDC5 remains poorly understood.	Nitrogen	4-5	fibronectin type III domain containing 5	Homo sapiens	23-28
31591270-10	2019	Mutations that reduced ARF1 N-terminal binding to the PH domain also reduced the effect of ASAP1 on cellular actin remodeling.	Nitrogen	28-29	ADP ribosylation factor 1	Homo sapiens	23-27
31591270-10	2019	Mutations that reduced ARF1 N-terminal binding to the PH domain also reduced the effect of ASAP1 on cellular actin remodeling.	Nitrogen	28-29	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	Homo sapiens	91-96
31591270-12	2019	We conclude that PIP2 regulates binding of ASAP1"s PH domain to the ARF1 N terminus, which may partially regulate GAP activity.	Nitrogen	73-74	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	Homo sapiens	43-48
31591270-12	2019	We conclude that PIP2 regulates binding of ASAP1"s PH domain to the ARF1 N terminus, which may partially regulate GAP activity.	Nitrogen	73-74	ADP ribosylation factor 1	Homo sapiens	68-72
31718774-5	2019	First, we show that Drosophila Efa6 can inhibit MTs directly without interacting molecules via an N-terminal 18 amino acid motif (MT elimination domain/MTED) that binds tubulin and inhibits microtubule growth in vitro and cells.	Nitrogen	98-99	Exchange factor for Arf 6	Drosophila melanogaster	31-35
31398529-5	2019	The genetic variation analysis showed that extensive amino acid substitutions happened in the significant regions of ORF5 including major linear antigenic epitopes (27-30aa, 37-45aa, 52-61aa) and the potential N-glycosylation sites (32-35aa).	Nitrogen	210-211	CWC15 spliceosome associated protein homolog	Homo sapiens	117-121
31260750-2	2019	Increasing dietary n-3 PUFA intake results in increased DHA and EPA content in cell membranes as well as an increase in n-3 derived oxylipin and -endocannabinoid concentrations, like fatty acid amides and glycerol-esters.	Nitrogen	19-21	pumilio RNA binding family member 3	Homo sapiens	23-27
28733331-4	2017	In the present study, we analysed N-glycosylation sites of FNDC5 and found that two potential N-glycosylation sites (Asn36 and Asn81) could indeed be occupied by N-glycan.	Nitrogen	34-35	fibronectin type III domain containing 5	Homo sapiens	59-64
28733331-6	2017	We also found that the expression level of N-glycosylated FNDC5 was elevated after myoblast differentiation.	Nitrogen	43-44	fibronectin type III domain containing 5	Homo sapiens	58-63
30351217-10	2019	These variant FMO3 proteins recombinantly expressed in Escherichia coli membranes exhibited decreased N-oxygenation activities toward trimethylamine (Vmax/Km &lt; 40% that of the wild-type).	Nitrogen	102-103	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	14-18
28733331-7	2017	These findings show that the secretion of irisin is modulated by N-glycosylation, which in turn enhances our understanding of the secretion of glycosylated irisin.	Nitrogen	65-66	fibronectin type III domain containing 5	Homo sapiens	42-48
31538686-3	2019	For spin crossover in first-row transition metals coordinated by hydrogen, nitrogen, and carbon monoxide, we find the pressure required for spin transition to be a function of ligand position in the spectrochemical sequence.	Nitrogen	75-83	spindlin 1	Homo sapiens	4-8
28733331-7	2017	These findings show that the secretion of irisin is modulated by N-glycosylation, which in turn enhances our understanding of the secretion of glycosylated irisin.	Nitrogen	65-66	fibronectin type III domain containing 5	Homo sapiens	156-162
31702394-3	2019	Materials &amp; methods: A series of HDAC inhibitors based on N-hydroxycinnamamide fragment was designed as the clinically used belinostat analog using amide as the connecting unit.	Nitrogen	62-82	histone deacetylase 9	Homo sapiens	37-41
31569820-2	2019	Structurally, Hsp70s are composed of an N-terminal nucleotide binding domain (NBD) which exhibits ATPase activity, and a C-terminal substrate binding domain (SBD).	Nitrogen	40-41	heat shock protein family A (Hsp70) member 4	Homo sapiens	14-19
28620050-4	2017	Hexa-Fc contains two N-linked sites at Asn-77 (equivalent to Asn-297 in the Fc of IgG1) and Asn-236 (equivalent to Asn-563 in the tail piece of IgM).	Nitrogen	21-22	hexosaminidase subunit alpha	Homo sapiens	0-4
31343787-4	2019	The stability is thought to originate from an intramolecular spin pairing between the N-donor and the NI acceptor post ET, which is demonstrated in supramolecular chemistry.	Nitrogen	86-87	spindlin 1	Homo sapiens	61-65
31603315-7	2019	Dynamics measurements revealed a dynamic hotspot of GlpG at the N-terminal part of TM5 and the adjacent loop L4, indicating that this region is important for gating.	Nitrogen	64-65	tropomyosin 3	Homo sapiens	83-86
28775280-6	2017	Using a solution of CsF in glycerol, we determine that 4 +- 2 x 1012 19F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.Nitrogen vacancy (NV) centres in diamond can be used for NMR spectroscopy, but increased sensitivity is needed to avoid long measurement times.	Nitrogen	168-176	colony stimulating factor 2	Homo sapiens	20-23
31671706-0	2019	Investigation of Site-Specific Differences in Glycan Microheterogeneity by N-Glycopeptide Mapping of VEGFR-IgG Fusion Protein.	Nitrogen	75-76	kinase insert domain receptor	Homo sapiens	101-106
31596290-1	2019	In this study, we present a crystal structure prediction and characterization for two novel single- and double-bonded nitrogen allotropes (denoted as CubN and DobN) bearing three-membered nitrogen cycles.	Nitrogen	118-126	cubilin	Homo sapiens	150-154
31596290-1	2019	In this study, we present a crystal structure prediction and characterization for two novel single- and double-bonded nitrogen allotropes (denoted as CubN and DobN) bearing three-membered nitrogen cycles.	Nitrogen	188-196	cubilin	Homo sapiens	150-154
31596290-3	2019	Due to the presence of strained nitrogen cycles, these allotropes are high-lying phases, which retain high energy densities at least up to 200 GPa, when CubN becomes lower in energy than zeta-N2.	Nitrogen	32-40	cubilin	Homo sapiens	153-157
31681742-9	2019	The effect of amino acid supplementation of the medium was investigated and the nitrogen metabolism of S. cerevisiae was altered by knock-out of TOR1 or YIH1.	Nitrogen	80-88	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	145-149
31649674-7	2019	We describe a website to search cAb-Rep for similar antibodies along with methods for analysis of the prevalence of antibodies with specific genetic signatures, for estimation of reproducibility of somatic hypermutation patterns of interest, and for delineating frequencies of somatically introduced N-glycosylation.	Nitrogen	300-301	neural proliferation, differentiation and control 1	Homo sapiens	32-35
31696472-9	2019	Inhibition of lncRNA AOC4P expression also can result in the decreased expression levels of extracellular-signal-regulated kinase 1 (ERK1), c-Jun N-terminal kinases (JNK) and p38 proteins.	Nitrogen	18-19	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	140-145
31377676-4	2019	RhIL-17A and rhIL-17F shared 96.8% and 93.9% amino acid sequence identity with human IL-17A (huIL-17A) and IL-17F (huIL-17F) respectively and the sequences also shared one N-glycosylation site and six conserved cysteine residues with huIL-17A and huIL-17F.	Nitrogen	172-173	interleukin 17A	Homo sapiens	2-8
31202607-5	2019	We found that removing putative N-glycosylation sites alters the functional properties of GluN1/GluN3B receptors, but has no effect on GluN1/GluN3A receptors.	Nitrogen	32-33	glutamate ionotropic receptor NMDA type subunit 3B	Homo sapiens	96-102
31285127-0	2019	A Roadmap for Lowering Crop Nitrogen Requirement.	Nitrogen	28-36	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	23-27
31285127-4	2019	We provide a roadmap to integrate the regulation of nitrogen uptake and assimilation into varietal selection and crop breeding programs.	Nitrogen	52-60	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	113-117
31240921-4	2019	In contrast, the element-element BDE trend for the 2p homologues is second pi &gt; first pi &gt; sigma for nitrogen and oxygen, and sigma &gt; first pi &gt; second pi for carbon.	Nitrogen	107-115	homeobox D13	Homo sapiens	33-36
31397148-0	2019	Development of Novel delta Opioid Receptor Inverse Agonists without a Basic Nitrogen Atom and Their Antitussive Effects in Mice.	Nitrogen	76-84	opioid receptor, delta 1	Mus musculus	21-42
31392770-5	2019	CNF-based 3D aerogels are prepared through a cryogenic process, so called ice-segregation-induced self-assembly (ISISA) consisting of the unidirectional immersion of an aqueous chitosan (CHI) solution also containing CNFs in suspension into a liquid nitrogen bath, and subsequent freeze-drying.	Nitrogen	250-258	NPHS1 adhesion molecule, nephrin	Homo sapiens	0-3
31326434-10	2019	An increase in blood urea nitrogen (p < 0.05), a marked increase of albumin level in urine (p < 0.01) and its concomitant decrease in serum (p < 0.05) were also detected in Parg-/-Parp-1-/- mice compared with the Parg+/+Parp-1-/- counterpart.	Nitrogen	26-34	poly (ADP-ribose) glycohydrolase	Mus musculus	173-177
30892644-9	2019	Among them, trans-acting siRNA3 (TAS3), which is known to promote lateral root development by producing siRNA against Auxin response factor 2, 3, and 4, was revealed as a nitrogen (N)-responsive lincRNA.	Nitrogen	171-179	TAS3	Arabidopsis thaliana	33-37
30892644-9	2019	Among them, trans-acting siRNA3 (TAS3), which is known to promote lateral root development by producing siRNA against Auxin response factor 2, 3, and 4, was revealed as a nitrogen (N)-responsive lincRNA.	Nitrogen	171-179	auxin response factor 2	Arabidopsis thaliana	118-151
31799945-2	2019	Under appropriate operating conditions, the B-MBR was capable of achieving excellent treated water quality in terms of biochemical oxygen demand and concentration of total nitrogen.	Nitrogen	172-180	translocator protein	Homo sapiens	46-49
31308178-0	2019	N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2).	Nitrogen	0-1	kinase insert domain receptor	Homo sapiens	71-116
31308178-0	2019	N-Glycosylation regulates ligand-dependent activation and signaling of vascular endothelial growth factor receptor 2 (VEGFR2).	Nitrogen	0-1	kinase insert domain receptor	Homo sapiens	118-124
31308178-2	2019	By altering the N-glycosylation machinery in the endoplasmic reticulum and Golgi, proinflammatory cytokines promote the modification of endothelial glycoproteins such as vascular endothelial growth factor receptor 2 (VEGFR2) with sialic acid-capped N-glycans.	Nitrogen	16-17	kinase insert domain receptor	Homo sapiens	170-215
31308178-2	2019	By altering the N-glycosylation machinery in the endoplasmic reticulum and Golgi, proinflammatory cytokines promote the modification of endothelial glycoproteins such as vascular endothelial growth factor receptor 2 (VEGFR2) with sialic acid-capped N-glycans.	Nitrogen	16-17	kinase insert domain receptor	Homo sapiens	217-223
31308178-7	2019	We propose that N-glycosylation, specifically the capping of N-glycans at Asn-247 by sialic acid, tunes ligand-dependent activation and signaling of VEGFR2 in endothelial cells.	Nitrogen	16-17	kinase insert domain receptor	Homo sapiens	149-155
31673305-1	2019	X-linked inhibitor of apoptosis protein (XIAP) is an important regulator of cancer cell survival whose BIR3 domain (XIAP-BIR3) recognizes the Smac N-terminal tetrapeptide sequence (AVPI), making it an attractive protein-protein interaction (PPI) target for cancer therapies.	Nitrogen	147-148	X-linked inhibitor of apoptosis	Homo sapiens	0-39
31673305-1	2019	X-linked inhibitor of apoptosis protein (XIAP) is an important regulator of cancer cell survival whose BIR3 domain (XIAP-BIR3) recognizes the Smac N-terminal tetrapeptide sequence (AVPI), making it an attractive protein-protein interaction (PPI) target for cancer therapies.	Nitrogen	147-148	X-linked inhibitor of apoptosis	Homo sapiens	41-45
31673305-1	2019	X-linked inhibitor of apoptosis protein (XIAP) is an important regulator of cancer cell survival whose BIR3 domain (XIAP-BIR3) recognizes the Smac N-terminal tetrapeptide sequence (AVPI), making it an attractive protein-protein interaction (PPI) target for cancer therapies.	Nitrogen	147-148	X-linked inhibitor of apoptosis	Homo sapiens	116-120
31210386-3	2019	We thus obtained two isomeric all-acceptor polymers, P1 and P2, which have the same backbone and side-chains but different positions of the nitrogen atoms in the thiazole units.	Nitrogen	140-148	crystallin gamma F, pseudogene	Homo sapiens	53-62
31432267-0	2019	A dual-channel ratiometric fluorescent probe for determination of the activity of tyrosinase using nitrogen-doped graphene quantum dots and dopamine-modified CdTe quantum dots.	Nitrogen	99-107	tyrosinase	Homo sapiens	82-92
31102952-6	2019	Under N2 atmosphere, the absorbed Hg was found as Hg2+, and coordinated to O atom.	Nitrogen	6-8	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	50-53
31616190-2	2019	The   R A N K L  O P G      ratio increases in periodontal disease.	Nitrogen	10-11	basic transcription factor 3 pseudogene 11	Homo sapiens	17-22
31616190-6	2019	Results: The findings of this study showed that the mean   R A N K L  O P G      ratio was significantly higher in the patients with periodontal disease than in the healthy controls (P=0.001).	Nitrogen	63-64	basic transcription factor 3 pseudogene 11	Homo sapiens	70-75
31616190-7	2019	Also, the   R A N K L  O P G      ratio was significantly higher in the patients with a higher mean CAL (P=0/004).	Nitrogen	16-17	basic transcription factor 3 pseudogene 11	Homo sapiens	23-28
31616190-9	2019	Conclusion: The results of this study showed a direct relationship between the   R A N K L  O P G      ratio and the severity of periodontal disease.	Nitrogen	85-86	basic transcription factor 3 pseudogene 11	Homo sapiens	92-97
31616190-11	2019	In other words, the   R A N K L  O P G      ratio can be a good predictor of treatment success.	Nitrogen	26-27	basic transcription factor 3 pseudogene 11	Homo sapiens	33-38
30973186-3	2019	EPO variants with an alkyne-bearing non-natural amino acid (Plk) at the N-glycosylation sites 24, 38, and 83 were obtained by amber suppression followed by protein purification and refolding.	Nitrogen	72-73	polo like kinase 1	Homo sapiens	60-63
31173188-2	2019	Secretagogin (Scgn), a Ca2+ sensor protein that is expressed at high levels in the islets, has been shown to play a key role in regulating insulin secretion through effects on the soluble N-ethylmaleimide-sensitive factor attachment receptor protein complexes.	Nitrogen	188-189	secretagogin, EF-hand calcium binding protein	Mus musculus	0-12
31173188-2	2019	Secretagogin (Scgn), a Ca2+ sensor protein that is expressed at high levels in the islets, has been shown to play a key role in regulating insulin secretion through effects on the soluble N-ethylmaleimide-sensitive factor attachment receptor protein complexes.	Nitrogen	188-189	secretagogin, EF-hand calcium binding protein	Mus musculus	14-18
30613975-0	2019	beta3 -adrenergic receptor activation plays an important role in the depressed myocardial contractility via both elevated levels of cellular free Zn2+ and reactive nitrogen species.	Nitrogen	164-172	adrenoceptor beta 3	Rattus norvegicus	0-26
31557890-7	2019	Collectively, these results revealed the under-estimated impact of n-3 PUFA supplementation as well as the importance of the n-6 to n-3 ratio on the formation of the skin barrier of in vitro reconstructed human skin models.	Nitrogen	42-43	pumilio RNA binding family member 3	Homo sapiens	71-75
31572984-7	2019	The Nrf2 activity of the compound NQC was determined using "Keap1:Nrf2 Inhibitor Screening Assay Kit".	Nitrogen	34-37	kelch-like ECH-associated protein 1	Mus musculus	60-65
31572984-13	2019	Molecular docking studies confirmed the favourable binding of NQC at Kelch domain of Keap-1.	Nitrogen	62-65	kelch-like ECH-associated protein 1	Mus musculus	85-91
31379033-0	2019	Microwave Energy Drives "On-Off-On" Spin-Switch Behavior in Nitrogen-Doped Graphene.	Nitrogen	60-68	spindlin 1	Homo sapiens	36-40
31379033-4	2019	The synthesis and electronic properties of nitrogen-doped graphene (N content: 9.8%), featuring both localized spin centers and spin-containing sites with itinerant electron properties, are reported.	Nitrogen	43-51	spindlin 1	Homo sapiens	111-115
31379033-4	2019	The synthesis and electronic properties of nitrogen-doped graphene (N content: 9.8%), featuring both localized spin centers and spin-containing sites with itinerant electron properties, are reported.	Nitrogen	43-51	spindlin 1	Homo sapiens	128-132
31327679-1	2019	For the purpose of synthesizing drug candidates with desirable bioactivity, a class of benzoyl amide containing nitrogen heterocyclic ring derivatives targeting VEGFR-2 was designed and screened out using Discovery Studio.	Nitrogen	112-120	kinase insert domain receptor	Homo sapiens	161-168
31055628-7	2019	Consistently, hypoxia-cultured PC12 cells (O2/N2/CO2, 1:94:5, 8 h) caused cellular injury (LDH release and necroposis) concomitant with up-regulation of necroptosis-associated proteins, and these phenomena were blocked in the presence of ligustroflavone (25 muM) except the elevated RIPK1 levels.	Nitrogen	46-48	receptor interacting serine/threonine kinase 1	Rattus norvegicus	283-288
31447026-5	2019	A subsequent electrolytic stage using Ti/IrO2-TaO2 anode at 175 mA cm-2 and 0.42 M NaCl during 60 min, led to overall organic matter and nitrogen removal above 85% and 90%, respectively, with energy requirement of 38 kWh per kg of nitrogen removed.	Nitrogen	137-145	TAO kinase 2	Homo sapiens	46-50
31447026-5	2019	A subsequent electrolytic stage using Ti/IrO2-TaO2 anode at 175 mA cm-2 and 0.42 M NaCl during 60 min, led to overall organic matter and nitrogen removal above 85% and 90%, respectively, with energy requirement of 38 kWh per kg of nitrogen removed.	Nitrogen	231-239	TAO kinase 2	Homo sapiens	46-50
31507595-1	2019	Human CD52 is a small glycopeptide (12 amino acid residues) with one N-linked glycosylation site at asparagine 3 (Asn3) and several potential O-glycosylation serine/threonine sites.	Nitrogen	69-70	CD52 molecule	Homo sapiens	6-10
31347824-2	2019	Herein, self-standing and binder-free porous N-Co carbon nanofiber (N-Co/CNF) cathodes are prepared for zinc-air batteries (ZABs) by an in situ electrospinning/plasma-etching method.	Nitrogen	45-46	NPHS1 adhesion molecule, nephrin	Homo sapiens	73-76
31387302-5	2019	Expression of several nitrogen-related response genes, including ASP5, ASP2, ASN3, ATCYSC1, PAL2, APT2, CRTISO, and COX15, was dramatically changed in the thick TPC lines compared to those in the thin TPC lines.	Nitrogen	22-30	prolycopene isomerase, chloroplastic	Brassica napus	104-110
31048249-4	2019	Based on Job"s plot and in situ mass spectra, two STH molecules will complex with Al3+ to form 2:1 complexation with oxygen atoms of hydroxyl and carbonyl groups and nitrogen atom of CN bond participating in coordination.	Nitrogen	166-174	saitohin	Homo sapiens	50-53
31359016-6	2019	Our results expand current knowledge of MFGM N-glycoproteomes, and further demonstrate the complexity and biological functions of MFGM N-glycosylation.	Nitrogen	45-46	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	40-44
31359016-6	2019	Our results expand current knowledge of MFGM N-glycoproteomes, and further demonstrate the complexity and biological functions of MFGM N-glycosylation.	Nitrogen	135-136	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	130-134
31147890-1	2019	Nitrogen-centered and beta-carbon-centered hydrogen-deficient peptide radicals are considered to be intermediates in the matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD)-induced Calpha-C bond cleavage of peptide backbones when using an oxidizing matrix.	Nitrogen	0-8	carbonic anhydrase 2	Homo sapiens	201-209
31147890-3	2019	The calculations indicate that the nitrogen-centered radical immediately undergoes Calpha-C bond cleavage, leading to the formation of an a /x fragment pair.	Nitrogen	35-43	carbonic anhydrase 2	Homo sapiens	83-91
31147890-8	2019	The intense signal arising from d fragments and the lack of or weak signal from a fragments strongly suggest that the Calpha-C bond cleavage occurs through a nitrogen-centered radical intermediate.	Nitrogen	158-166	carbonic anhydrase 2	Homo sapiens	118-126
30949952-9	2019	Notably, supplementation of n-3 PUFA prevented the majority of the modifications caused by the chronic administration of L-tyrosine in the cerebral enzyme activities, as well as ameliorated the oxidative stress in the brain regions of rats.	Nitrogen	17-18	pumilio RNA binding family member 3	Homo sapiens	32-36
31417508-10	2019	In addition, we evaluated the fermentative capacities of the hemizygous strains under low nitrogen conditions, observing an antagonistic effect for KAE1 SA allele, where the hemizygous strain containing this allele presented the lower fermentation rate.	Nitrogen	90-98	tRNA N6-adenosine threonylcarbamoyltransferase	Saccharomyces cerevisiae S288C	148-152
31298844-0	2019	An Isoform-Selective PTP1B Inhibitor Derived from Nitrogen-Atom Augmentation of Radicicol.	Nitrogen	50-58	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	21-26
31298844-3	2019	This nitrogen-atom augmented radicicol derivative was found to be PTP1B selective relative to other highly homologous nonreceptor PTPs.	Nitrogen	5-13	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	66-71
31094028-5	2019	RESULTS: Pre-treatment with G-Rb3 at doses of 10 and 20 mg/kg for ten days significantly reversed the increases in serum creatinine (CRE), blood urea nitrogen (BUN) and malondialdehyde (MDA), and decrease in glutathione (GSH) content and superoxide dismutase (SOD) activity.	Nitrogen	150-158	stathmin 4	Homo sapiens	30-33
30952307-4	2019	PB1 showed a highly selectivity response to H2O2 over other reactants such as reactive oxygen/nitrogen species, biothiols and various ions in aqueous solution at physiological pH.	Nitrogen	94-102	polybromo 1	Homo sapiens	0-3
31602841-1	2019	To study the effects of saikosaponin b2( SS-b2) on inflammatory factors and energy metabolism against lipopolysaccharide/galactosamine( LPS/Gal N) induced acute liver injury in mice.	Nitrogen	144-145	nucleic acid binding protein 1	Mus musculus	41-46
31602841-21	2019	01).In summary,SS-b2 has a significant protective effect on LPS/Gal N-induced acute liver injury in mice,which may be related to the down-regulation of NF-kappaB protein expression and up-regulation of Sirt-6 protein expression to improve inflammatory injury and energy metabolism.	Nitrogen	68-69	nucleic acid binding protein 1	Mus musculus	15-20
30928749-7	2019	In terms of the Baltic Sea ecosystem functioning, continuous input of ship-borne nitrogen is compensated by steady decrease of nitrogen fixation and increase of denitrification, which results in stationary level of total nitrogen content in the water.	Nitrogen	127-135	inositol polyphosphate-5-phosphatase D	Homo sapiens	70-74
30928749-7	2019	In terms of the Baltic Sea ecosystem functioning, continuous input of ship-borne nitrogen is compensated by steady decrease of nitrogen fixation and increase of denitrification, which results in stationary level of total nitrogen content in the water.	Nitrogen	127-135	inositol polyphosphate-5-phosphatase D	Homo sapiens	70-74
30892746-5	2019	These include the cycloaddition of ethyl isocyanate to 2 A affording [Na2 (THF)5 ]{L2 Ga[EtN-C(O)]2 GaL2 } (6), cleavage of the N=C bond with release of 1 equiv.	Nitrogen	70-71	galectin 2	Homo sapiens	100-104
31184154-4	2019	NUE of B. napus increased under LN, which enhanced N uptake ability by regulating root system architecture and plasma membrane H+-ATPase activity; AUX1 was involved in this process.	Nitrogen	0-1	Transmembrane amino acid transporter family protein	Arabidopsis thaliana	147-151
31187243-0	2019	An electrochemical sandwich immunosensor for cardiac troponin I by using nitrogen/sulfur co-doped graphene oxide modified with Au@Ag nanocubes as amplifiers.	Nitrogen	73-81	troponin I3, cardiac type	Homo sapiens	45-63
31187243-9	2019	Graphical abstract Schematic presentation of cardiac troponin I (cTnI) electrochemical immunosensor based on gold nanocube-functionalized graphene oxide (AuNC/GO) as substrate material, bimetallic gold/silver core-shell nanocubes and nitrogen and sulfur co-doped reduced graphene oxide (Au@AgNC/N, S-rGO) as signal amplifier, and hydrogen peroxide (H2O2) and o-phenylenediamine (o-PD) as redox probe.	Nitrogen	234-242	troponin I3, cardiac type	Homo sapiens	45-63
31187243-9	2019	Graphical abstract Schematic presentation of cardiac troponin I (cTnI) electrochemical immunosensor based on gold nanocube-functionalized graphene oxide (AuNC/GO) as substrate material, bimetallic gold/silver core-shell nanocubes and nitrogen and sulfur co-doped reduced graphene oxide (Au@AgNC/N, S-rGO) as signal amplifier, and hydrogen peroxide (H2O2) and o-phenylenediamine (o-PD) as redox probe.	Nitrogen	234-242	troponin I3, cardiac type	Homo sapiens	65-69
31117680-3	2019	Here, we describe a rational design of nonnoble metal-embedding and nitrogen-containing carbon nanofiber (M-CNF) catalysts.	Nitrogen	68-76	NPHS1 adhesion molecule, nephrin	Homo sapiens	108-111
31124676-4	2019	Mechanistic studies indicate that the C-N bond formation occurs via a syn amino-palladation mechanism, an insight which may guide future reaction development given the limited number of enantioselective syntheses of alpha-tertiary amines.	Nitrogen	40-41	synemin	Homo sapiens	70-73
30981741-10	2019	In addition, the function of multiple glycosyltransferases required for N- and O-glycosylation were impaired in DOP1-shutdown cells.	Nitrogen	72-73	Dop1p	Saccharomyces cerevisiae S288C	112-116
30925289-6	2019	We also found that N-GQDs activated the cytochrome P450 monooxygenase (e.g. cyp1a) and the associated aryl-hydrocarbon receptor repressors (ahrr1 and ahrr2) in zebrafish embryos.	Nitrogen	19-20	cytochrome P450, family 2, subfamily AA, polypeptide 9	Danio rerio	40-69
30925289-6	2019	We also found that N-GQDs activated the cytochrome P450 monooxygenase (e.g. cyp1a) and the associated aryl-hydrocarbon receptor repressors (ahrr1 and ahrr2) in zebrafish embryos.	Nitrogen	19-20	aryl hydrocarbon receptor 1a	Danio rerio	102-127
31066384-4	2019	With high nitrogen contents (59.6-76.8%) and tremendous ring-strain energy, these fused compounds exhibit high positive heats of formation ranging from 2.35 to 4.23 kJ g-1, much higher than those of RDX (0.32 kJ g-1) and HMX (0.25 kJ g-1).	Nitrogen	10-18	radixin	Homo sapiens	199-202
31091274-15	2019	We conclude that Ninjurin1 contributes to myocyte growth and differentiation, and that these effects are mainly mediated by N-glycosylated Ninjurin1-24.	Nitrogen	17-18	ninjurin 1	Homo sapiens	139-151
30964290-6	2019	Furthermore, docking into human HDAC10 homology models indicated that a hydrogen bond between a cap group nitrogen and the gatekeeper residue Glu272 was responsible for potent HDAC10 binding.	Nitrogen	106-114	histone deacetylase 10	Homo sapiens	32-38
30964290-6	2019	Furthermore, docking into human HDAC10 homology models indicated that a hydrogen bond between a cap group nitrogen and the gatekeeper residue Glu272 was responsible for potent HDAC10 binding.	Nitrogen	106-114	histone deacetylase 10	Homo sapiens	176-182
31356625-5	2019	Silencing by RNA interference of the soluble N-ethylmaleimide-sensitive-factor attachment protein receptors Sec22b and syntaxin-5, which regulate ER-Golgi trafficking, identified these host proteins as components of the machinery that mediates the spreading of Leishmania effectors within host cells.	Nitrogen	14-15	syntaxin 5	Homo sapiens	119-129
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	35-36	heat shock protein family A (Hsp70) member 4	Homo sapiens	158-163
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	35-36	heat shock protein family A (Hsp70) member 4	Homo sapiens	165-186
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	54-55	heat shock protein family A (Hsp70) member 4	Homo sapiens	158-163
31147442-3	2019	JMJD6 is also reported to catalyze N-demethylation of N-methylated (both mono- and di-methylated) arginine residues of histones and other proteins, including HSP70 (heat-shock protein 70), estrogen receptor alpha, and RNA helicase A.	Nitrogen	54-55	heat shock protein family A (Hsp70) member 4	Homo sapiens	165-186
31324887-0	2019	Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.	Nitrogen	14-15	KRAS proto-oncogene, GTPase	Homo sapiens	37-41
31297616-10	2019	Graphical abstract Schematic presentation of the fluorometric assay of atrazine detection based on tyrosinase-induced fluorescence (FL) quenching effect on the nitrogen-doped graphene quantum dots (N-GQDs) and inhibitory effect of atrazine on tyrosinase.	Nitrogen	160-168	tyrosinase	Homo sapiens	99-109
31297616-10	2019	Graphical abstract Schematic presentation of the fluorometric assay of atrazine detection based on tyrosinase-induced fluorescence (FL) quenching effect on the nitrogen-doped graphene quantum dots (N-GQDs) and inhibitory effect of atrazine on tyrosinase.	Nitrogen	160-168	tyrosinase	Homo sapiens	243-253
31278267-2	2019	Here we report the synthesis of metallic, ultraincompressible (K0 = 428(10) GPa), and very hard (nanoindentation hardness 36.7(8) GPa) rhenium nitride pernitride Re2(N2)(N)2.	Nitrogen	166-168	G protein-coupled receptor 161	Homo sapiens	162-165
31278267-4	2019	Re2(N2)(N)2 can be obtained via a reaction between rhenium and nitrogen in a diamond anvil cell at pressures from 40 to 90 GPa and is recoverable at ambient conditions.	Nitrogen	63-71	G protein-coupled receptor 161	Homo sapiens	0-3
31084870-3	2019	Our previous study found that ferredoxin NADP+ oxidoreductase (FNR1) and the blue-light receptor cryptochrome 1 (CRY1) are involved in nitrogen-regulated flowering-time control.	Nitrogen	135-143	ferredoxin-NADP[+]-oxidoreductase 1	Arabidopsis thaliana	63-67
31084870-3	2019	Our previous study found that ferredoxin NADP+ oxidoreductase (FNR1) and the blue-light receptor cryptochrome 1 (CRY1) are involved in nitrogen-regulated flowering-time control.	Nitrogen	135-143	cryptochrome 1	Arabidopsis thaliana	97-111
31067280-1	2019	Golgi alpha-mannosidase II (GMII) is a glycoside hydrolase playing a crucial role in the N-glycosylation pathway.	Nitrogen	89-90	mannosidase alpha class 2A member 1	Homo sapiens	0-26
31067280-1	2019	Golgi alpha-mannosidase II (GMII) is a glycoside hydrolase playing a crucial role in the N-glycosylation pathway.	Nitrogen	89-90	mannosidase alpha class 2A member 1	Homo sapiens	28-32
31084870-3	2019	Our previous study found that ferredoxin NADP+ oxidoreductase (FNR1) and the blue-light receptor cryptochrome 1 (CRY1) are involved in nitrogen-regulated flowering-time control.	Nitrogen	135-143	cryptochrome 1	Arabidopsis thaliana	113-117
30698750-5	2019	The Arg/N-end rule and VCP/p97UFD1-NPL4 segregase cooperate to promote phosphorylation-dependent, chromatin-associated Lys-SDE2Ct degradation upon UVC damage.	Nitrogen	8-9	SDE2 telomere maintenance homolog	Homo sapiens	123-127
30582279-5	2019	Taking into account the in silico findings, MMP-9 can be considered a potential target of oxaprozin, which seems to be able to chelate the catalytic zinc ion through the nitrogen of the oxazole ring and the carboxylate moiety.	Nitrogen	170-178	matrix metallopeptidase 9	Homo sapiens	44-49
31293392-16	2019	In this case, reduction of both neonatal N- (P5) and more mature P/Q-type currents (around/after hearing onset) may contribute to the impaired morphology and function of endbulb synapses in alpha2delta3-deficient mice.	Nitrogen	41-42	calcium channel, voltage-dependent, alpha2/delta subunit 3	Mus musculus	190-202
30928749-7	2019	In terms of the Baltic Sea ecosystem functioning, continuous input of ship-borne nitrogen is compensated by steady decrease of nitrogen fixation and increase of denitrification, which results in stationary level of total nitrogen content in the water.	Nitrogen	81-89	inositol polyphosphate-5-phosphatase D	Homo sapiens	70-74
28645189-6	2017	RARalpha displayed a renoprotective role in GS rats, resulting in a lower GS index, podocyte foot process fusion, and proteinuria, reduced serum creatinine and blood urea nitrogen.	Nitrogen	171-179	retinoic acid receptor, alpha	Rattus norvegicus	0-8
31221135-12	2019	Slc3a1-/- mice on a regular diet demonstrated elevated blood urea nitrogen (BUN) without elevation of serum creatinine.	Nitrogen	66-74	solute carrier family 3, member 1	Mus musculus	0-6
31114894-5	2019	This is the first demonstration of the AlkB proteins to oxidize a methyl group attached to carbon, instead of nitrogen, on a DNA base.	Nitrogen	110-118	alkB homolog 1, histone H2A dioxygenase	Homo sapiens	39-43
30848861-4	2019	METHODS AND RESULTS: The n-3 PUFA precursor, alpha-linolenic acid (ALA), or its derivatives, eicosapentaenoic, or docosahexaenoic acid, is added to co-cultures of human ob-ASCs and mononuclear cells (MNCs).	Nitrogen	25-26	pumilio RNA binding family member 3	Homo sapiens	29-33
31020291-1	2019	Differences in the electronegativity and hydrophilicity of halogens lead to differences in proton-conducting and photoluminescence properties in hybrid organic-inorganic lead halide compounds of [PbX2(OOCMMIm)]n (X = Cl (1), Br (2), HOOCMMIm = 1-carboxymethyl-3-methylimidazolium).	Nitrogen	7-8	PBX homeobox 2	Homo sapiens	196-200
30864841-4	2019	Mice lacking VDR developed more severe AKI than wild-type (WT) control mice after LPS treatment, which was manifested by marked increases in body weight loss and accumulation of serum blood urea nitrogen and creatinine as well as the magnitude of apoptosis of tubular epithelial cells.	Nitrogen	195-203	vitamin D (1,25-dihydroxyvitamin D3) receptor	Mus musculus	13-16
30803063-3	2019	The as-prepared single atoms, supported by N-doped carbon flake arrays grown on carbon nanofibers assembly (M SA@NCF/CNF), demonstrate the dual characteristics of excellent catalytic activity (reversible oxygen overpotential of 0.75 V) and high stability, owing to the greatly improved active sites" accessibility and optimized single-sites/pore-structures correlations.	Nitrogen	43-44	NPHS1 adhesion molecule, nephrin	Homo sapiens	117-120
30246502-8	2019	Furthermore, we demonstrated that N-glycosylation mutation of EpCAM-mediated invasion and metastasis of breast carcinoma cells required the downregulation of MMP-9 via inhibition of these two signaling pathways.	Nitrogen	34-35	matrix metallopeptidase 9	Homo sapiens	158-163
30865649-6	2019	Average NH4+ fluxes at restored sites ranged from -8.9 to 5.0 mug N m-2 sec-1, however restoration did not significantly influence NH4+ uptake or regeneration (i.e., a measure of release to surface water) between 0-3 minutes and 3-10 minutes.	Nitrogen	8-9	secretory blood group 1, pseudogene	Homo sapiens	72-77
30865649-7	2019	Further, average NO3- fluxes amongst sites responded significantly between 0-3 minutes ranging from -33.6 to 97.7 mug N m-2 sec-1.	Nitrogen	17-18	secretory blood group 1, pseudogene	Homo sapiens	124-129
30562194-7	2019	Arterial spin labeling was eligible as a predictor for long PFS only in assessment of fluctuations in T/N ratio.	Nitrogen	104-105	spindlin 1	Homo sapiens	9-13
30818362-4	2019	Our data reveal Dal80 binding to a large set of promoters, sometimes independently of GATA sites, correlating with nitrogen- and/or Dal80-sensitive gene expression.	Nitrogen	115-123	Dal80p	Saccharomyces cerevisiae S288C	16-21
30794613-7	2019	Our study revealed the contributing effect of Wnt/beta-catenin pathway inhibition by FH535 and its derivative (FH535-N) through disruption of the autophagic flux in HCC cells.	Nitrogen	117-118	catenin (cadherin associated protein), beta 1	Mus musculus	50-62
30770792-3	2019	Smac mimetics such as BV6 selectively inhibit apoptosis triggered by pharmacological or genetic inhibition of protein N-glycosylation using TM or knockdown of DPAGT1, the enzyme that catalyzes the first step of protein N-glycosylation.	Nitrogen	219-220	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	159-165
30612271-0	2019	Insights into the effects of N-glycosylation on the characteristics of the VC1 domain of the human receptor for advanced glycation end products (RAGE) secreted by Pichia pastoris.	Nitrogen	29-30	advanced glycosylation end-product specific receptor	Homo sapiens	99-143
30612271-0	2019	Insights into the effects of N-glycosylation on the characteristics of the VC1 domain of the human receptor for advanced glycation end products (RAGE) secreted by Pichia pastoris.	Nitrogen	29-30	advanced glycosylation end-product specific receptor	Homo sapiens	145-149
30599307-7	2019	The two genes of asparagine synthetase (ZmAS3 and ZmAS4), which are responsible for nitrogen remobilization in leaves, were also significantly induced by the drought treatment.	Nitrogen	84-92	LOC100856906	Zea mays	17-38
30126018-2	2019	In most cases, their phosphorus atoms are bound to heteroatoms such as oxygen or nitrogen (PN3 or PN2 O), whereas homoleptic coordination by three sp2 -hybridized carbon atoms has been reported only recently.	Nitrogen	81-89	sodium voltage-gated channel alpha subunit 10	Homo sapiens	91-94
30571130-0	2019	(CH3)2CuLi/Cu(OTf)2 Mediated N- or O-Cyclization of Urea-Tethered Cyclobuta[ b]indolines.	Nitrogen	29-30	POU class 2 homeobox 2	Homo sapiens	14-19
30571130-1	2019	A (CH3)2CuLi/Cu(OTf)2 mediated N- or O-cyclization of urea-tethered cyclobuta[ b]indolines has been reported in this paper, giving a new synthetic protocol for the construction of pyrimido[1,6- a]indolone and cyclic imidate derivatives in moderate to good yields with a broad substrate scope under mild conditions.	Nitrogen	31-32	POU class 2 homeobox 2	Homo sapiens	16-21
31554776-0	2019	The Nitrogen Cycle: A Large, Fast, and Mystifying Cycle.	Nitrogen	4-12	fast	None	29-33
30525667-2	2018	Substitution at the nitrogen atom in simple benzamides with Ts and acyl or carbamate groups provides a unique way to achieve almost perpendicular twist in N-acyclic amides (tau = 77 , N = Ac; tau = 87 , N = Boc).	Nitrogen	20-28	BOC cell adhesion associated, oncogene regulated	Homo sapiens	207-210
30457862-1	2018	Topological analysis reveals stronger bonding for the N-NO2 bond relative to energetic nitramines RDX and HMX and the indication of a trend between this and impact sensitivity of nitro-containing energetic materials is noted.	Nitrogen	54-55	radixin	Homo sapiens	98-101
30403845-5	2018	In contrast, the mean Fe-N distances and  Fe-N-Fe angles correlate linearly with the [Fe6] oxidation level, or alternatively, the changes observed within the local Fe-N4 coordination planes vary linearly with the aggregate spin ground state.	Nitrogen	25-26	spindlin 1	Homo sapiens	223-227
30306993-2	2018	developed an efficient and mild method for CO oxidation by N2O to give CO2 and N2 catalyzed by a (PNN)Ru-H pincer complex.	Nitrogen	59-61	pinin, desmosome associated protein	Homo sapiens	98-101
30335938-3	2018	Here we operate high-performing [Super Yellow/trimethylolpropane ethoxylate/lithium trifluoromethanesulfonate (Li+CF3SO3-)] LEC devices inside a time-of-flight secondary ion mass spectrometer and cool the devices after different operation times to liquid nitrogen temperatures before depth profiling is performed.	Nitrogen	255-263	C-C motif chemokine ligand 16	Homo sapiens	124-127
30400227-0	2018	Highly Photoluminescent and Stable N-Doped Carbon Dots as Nanoprobes for Hg2+ Detection.	Nitrogen	35-36	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	73-76
31023104-2	2019	The nitrogen-containing BPs (NBPs) target osteoclast activity by disrupting protein prenylation via inhibition of farnesyl diphosphate synthase (FDPS).	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	114-143
31023104-2	2019	The nitrogen-containing BPs (NBPs) target osteoclast activity by disrupting protein prenylation via inhibition of farnesyl diphosphate synthase (FDPS).	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	145-149
30973873-5	2019	Dhh1 directly associates with ATG1 and ATG13 mRNAs under nitrogen-starvation conditions.	Nitrogen	57-65	autophagy related 13	Homo sapiens	39-44
30813732-2	2019	In the current scenario, from the same pyridino-alkyne substrates, the use of the external oxidant PhI(OAc)2, in combination with Cu(OTf)2, gave N-doped spiro-PAHs via a dearomative 1,2-carboamination process; whereas, without the use of oxidant, an alkyne/azadiene [4 + 2]-cycloaddition cascade occurred to exclusively afford ionic N-doped PAHs.	Nitrogen	145-146	POU class 2 homeobox 2	Homo sapiens	130-138
30908058-2	2019	Using ketones as N-alkylation reagent for indoles has been a great challenge not only because of the competing alkylation reaction of C-3 position but also because of the poor nucleophilicity of the nitrogen atom of indole, in addition to the steric hindrance and lower electrophilicity of the ketones.	Nitrogen	17-18	complement C3	Homo sapiens	134-137
30221828-7	2019	Moreover, a detailed mass spectrometric ESI-LC-MS/MS characterization of glycans at each of the three N-glycosylation sites of EPO showed that the 1st N-site is highly sialylated and either the negative impact of NaBu or the beneficial effect 1,3,4-O-Bu3 ManNAc treatments mainly affects the 2nd and 3rd N-glycan sites of EPO protein.	Nitrogen	102-103	erythropoietin	Cricetulus griseus	127-130
30221828-7	2019	Moreover, a detailed mass spectrometric ESI-LC-MS/MS characterization of glycans at each of the three N-glycosylation sites of EPO showed that the 1st N-site is highly sialylated and either the negative impact of NaBu or the beneficial effect 1,3,4-O-Bu3 ManNAc treatments mainly affects the 2nd and 3rd N-glycan sites of EPO protein.	Nitrogen	151-152	erythropoietin	Cricetulus griseus	127-130
30711708-7	2019	The exposure of A549 cells to Ag/N-TiO2 NPs determine the activation of ERK1/2 MAP-kinase pathway and the release of pro-inflammatory mediators CXCL1, GM-CSF and MIF, known to be involved in the recruitment of circulating neutrophils and monocytes.	Nitrogen	33-34	C-X-C motif chemokine ligand 1	Homo sapiens	144-149
30718375-3	2019	Glutamine transport by ASCT2 is proposed to be important for glutamine homoeostasis in rapidly growing cancer cells to fulfill the energy and nitrogen demands of these cells.	Nitrogen	142-150	solute carrier family 1 member 5	Homo sapiens	23-28
30599182-8	2019	Inhibitor of Syk signaling, R406 led to improvement of sepsis-induced AKI as depicted by an attenuation of creatinine/blood urea nitrogen in serum, renal myeloperoxidase activity, and repair of tubular structures in kidney.	Nitrogen	129-137	spleen tyrosine kinase	Mus musculus	13-16
30369550-8	2019	SNIPER(BRD)-3 contained an N-methylated LCL-161 derivative as the IAP ligand, which prevented it from binding IAPs, and resulted in the abrogated degradation of cIAP1, XIAP, and BRD4.	Nitrogen	1-2	magnesium transporter 1	Homo sapiens	66-69
30369550-8	2019	SNIPER(BRD)-3 contained an N-methylated LCL-161 derivative as the IAP ligand, which prevented it from binding IAPs, and resulted in the abrogated degradation of cIAP1, XIAP, and BRD4.	Nitrogen	1-2	X-linked inhibitor of apoptosis	Homo sapiens	168-172
30036888-0	2019	QSAR Models for Nitrogen Containing Monophosphonate and Bisphosphonate Derivatives as Human Farnesyl Pyrophosphate Synthase Inhibitors Based on Monte Carlo Method.	Nitrogen	16-24	farnesyl diphosphate synthase	Homo sapiens	92-123
30565390-6	2019	We also demonstrated that CTSB/BRCA1-dependent DNA damage was critical for RD-N, but not for etoposide, reinforcing the importance of CTSB/BRCA1 in RD-N-mediated cell death.	Nitrogen	48-49	cathepsin B	Homo sapiens	26-30
30565390-6	2019	We also demonstrated that CTSB/BRCA1-dependent DNA damage was critical for RD-N, but not for etoposide, reinforcing the importance of CTSB/BRCA1 in RD-N-mediated cell death.	Nitrogen	48-49	BRCA1 DNA repair associated	Homo sapiens	31-36
30565390-6	2019	We also demonstrated that CTSB/BRCA1-dependent DNA damage was critical for RD-N, but not for etoposide, reinforcing the importance of CTSB/BRCA1 in RD-N-mediated cell death.	Nitrogen	48-49	cathepsin B	Homo sapiens	134-138
30565390-6	2019	We also demonstrated that CTSB/BRCA1-dependent DNA damage was critical for RD-N, but not for etoposide, reinforcing the importance of CTSB/BRCA1 in RD-N-mediated cell death.	Nitrogen	48-49	BRCA1 DNA repair associated	Homo sapiens	139-144
30513349-7	2019	We were able to show that the N-linked glyco-structures of rhA1AT and rhC1INH are homogeneous and similar to the structures obtained from plasma-derived A1AT and C1INH, marketed as Prolastin -C and Cinryze , respectively.	Nitrogen	30-31	serpin family G member 1	Homo sapiens	72-77
30513135-1	2019	Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues.	Nitrogen	156-164	protein arginine methyltransferase 7	Homo sapiens	0-36
30513135-1	2019	Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues.	Nitrogen	156-164	protein arginine methyltransferase 7	Homo sapiens	38-43
30388580-5	2019	The optimal hydraulic retention time and interval time for biomass harvesting of FPCO-PBR were both 2 d. Nitrogen and phosphorus recovery rate were 30 mg L-1 d-1 and 7 mg L-1 d-1 respectively under optimal operating parameters.	Nitrogen	105-113	translocator protein	Homo sapiens	86-89
31063103-8	2019	The predicted N-linked glycosylation site between amino acids 6 and 8 in the V3 region was conserved in CCR5 viruses, but not in CXCR4 viruses.	Nitrogen	14-15	C-C motif chemokine receptor 5	Homo sapiens	104-108
30563719-0	2019	Chronic dietary changes in n-6/n-3 polyunsaturated fatty acid ratios cause developmental delay and reduce social interest in mice.	Nitrogen	4-5	notch 3	Mus musculus	31-34
31276181-8	2019	RESULTS: The relative expression of GATA-3 mRNA and protein in the E-N group was significantly higher than in the D-N group and E-siG3 group (P &lt; 0.05).	Nitrogen	45-46	GATA binding protein 3	Homo sapiens	36-42
31252287-8	2019	Using the cut-off values derived from the ROCs to define N positivity, there was weak concordance between NfL and all three MRI-derived metrics of N in the subsample of 285 individuals (Cohen"s Kappas <=0.429).	Nitrogen	57-58	neurofilament light chain	Homo sapiens	106-109
30563061-0	2018	Involvement of Glutaredoxin and Thioredoxin Systems in the Nitrogen-Fixing Symbiosis between Legumes and Rhizobia.	Nitrogen	59-67	trxA2	Sinorhizobium meliloti	32-43
30205091-2	2018	Methadone undergoes N-demethylation by multiple cytochrome P450 (CYP) enzymes including CYP3A4, CYP2B6, CYP2C19, CYP2D6, CYP2C9, and CYP2C8.	Nitrogen	20-21	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	104-111
30713787-0	2019	The multi-functionality of N-809, a novel fusion protein encompassing anti-PD-L1 and the IL-15 superagonist fusion complex.	Nitrogen	27-28	interleukin 15	Homo sapiens	89-94
30301783-3	2018	We have previously reported that fission yeast (Schizosaccharomyces pombe) Tf2 retrotransposons (hereafter Tf2s) are abnormally induced upon nitrogen starvation in cells lacking the tsc2+ gene (Deltatsc2), a homolog of the human TSC2 gene, and in cells with a dominant-active mutation in the fission yeast RHEB GTPase (rhb1-DA4).	Nitrogen	141-149	TSC complex subunit 2	Homo sapiens	182-186
30301783-3	2018	We have previously reported that fission yeast (Schizosaccharomyces pombe) Tf2 retrotransposons (hereafter Tf2s) are abnormally induced upon nitrogen starvation in cells lacking the tsc2+ gene (Deltatsc2), a homolog of the human TSC2 gene, and in cells with a dominant-active mutation in the fission yeast RHEB GTPase (rhb1-DA4).	Nitrogen	141-149	TSC complex subunit 2	Homo sapiens	229-233
30256635-3	2018	The calculated reaction mechanism demonstrates that biocatalysts capable of tertiary amide bond hydrolysis capitalize on anti nucleophilic attack and protonation of the amide nitrogen, in contrast to the traditional syn displayed by amidases and proteases acting on secondary amide bonds.	Nitrogen	175-183	synemin	Homo sapiens	216-219
30429888-10	2018	Results: ALP-(MIs)n/DOX effectively accumulated in gliomas and could reach the hypoxic glioma site after systemic in vivo administration.	Nitrogen	18-19	ATHS	Homo sapiens	9-12
30149019-10	2018	The N-acetylation capacity of NAT2 in the presence of SIRT1 enhancer was significantly decreased (p &lt; 0.001), conversely, the transient silencing of SIRT1 resulted in an increase of N-acetylation capacity (p &lt; 0.001).	Nitrogen	4-5	sirtuin 1	Homo sapiens	54-59
30149019-10	2018	The N-acetylation capacity of NAT2 in the presence of SIRT1 enhancer was significantly decreased (p &lt; 0.001), conversely, the transient silencing of SIRT1 resulted in an increase of N-acetylation capacity (p &lt; 0.001).	Nitrogen	4-5	sirtuin 1	Homo sapiens	152-157
29981898-5	2018	Using an off-line HPLC-MALDI-TOF-MS approach combined with exoglycosidase digestions and MS/MS, we reveal that the multiple hexose residues of the N-glycans of the gly-12;gly-13;gly-14 triple mutant are not just mannose, but include galactoses in three different positions (beta-intersecting, beta-bisecting and alpha-terminal) on isomeric forms of Hex4-8HexNAc2 structures; some of these structures are fucosylated and/or methylated.	Nitrogen	147-148	Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Caenorhabditis elegans	171-177
30243592-3	2018	Starting from a fragment, we discovered a novel series of potent covalent irreversible Btk inhibitors that bear N-linked groups occupying the solvent accessible pocket (SAP) of the active site of the Btk kinase domain.	Nitrogen	112-113	Bruton tyrosine kinase	Homo sapiens	87-90
30243592-3	2018	Starting from a fragment, we discovered a novel series of potent covalent irreversible Btk inhibitors that bear N-linked groups occupying the solvent accessible pocket (SAP) of the active site of the Btk kinase domain.	Nitrogen	112-113	Bruton tyrosine kinase	Homo sapiens	200-203
30217930-7	2018	Moreover, PTEN or PI3K/AKT/mTOR signaling could affect DPAGT1, a glycosylating enzyme involved in the initial step of N-linked glycosylation, to inhibit glycosylation of NIS.	Nitrogen	13-14	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	55-61
30374089-6	2018	Our findings identified ORE1 as a downstream target of NLA/PHO2 (UBC24) and showed that post-translational regulation of ORE1 levels determines leaf senescence during nitrogen deficiency.	Nitrogen	167-175	phosphate 2	Arabidopsis thaliana	59-63
30374089-6	2018	Our findings identified ORE1 as a downstream target of NLA/PHO2 (UBC24) and showed that post-translational regulation of ORE1 levels determines leaf senescence during nitrogen deficiency.	Nitrogen	167-175	phosphate 2	Arabidopsis thaliana	65-70
30348313-0	2018	N-glycosylation of tomato nuclease TBN1 produced in N. benthamiana and its effect on the enzyme activity.	Nitrogen	0-1	endonuclease precursor-like	Solanum lycopersicum	35-39
30047210-2	2018	Herein, activated cobalt-nitrogen-doped carbon nanotube/carbon nanofiber composites (Co-N-CNT/CNF) as the effective cathodes for Li-O2 batteries are prepared by in situ chemical vapor deposition (CVD).	Nitrogen	25-33	NPHS1 adhesion molecule, nephrin	Homo sapiens	94-97
27271094-10	2017	There was a statistically significant interaction between APOA2 polymorphism and n-6 PUFA intake on 8-isoprostane F2alpha concentration as well as n-3 PUFA intake on serum SOD activity (p-interaction = 0.04 and 0.02, respectively).	Nitrogen	29-30	apolipoprotein A2	Homo sapiens	58-63
30047210-4	2018	Meanwhile, the nitrogen-doped carbon nanotube/carbon nanofiber (N-CNT/CNF) and Co/CoNx serve as reaction sites to promote the formation/decomposition of discharge product.	Nitrogen	15-23	NPHS1 adhesion molecule, nephrin	Homo sapiens	70-73
30028989-5	2018	N-ac(d-Ala2)GIP/GLP-1-exe significantly (P &lt; 0.001) stimulated insulin secretion from BRIN-BD11 cells and isolated mouse islets, and evoked dose-dependent increases (P &lt; 0.001) in cAMP production in both GIP-R and GLP-1-R transfected cells.	Nitrogen	0-2	glucagon	Rattus norvegicus	16-21
30028989-5	2018	N-ac(d-Ala2)GIP/GLP-1-exe significantly (P &lt; 0.001) stimulated insulin secretion from BRIN-BD11 cells and isolated mouse islets, and evoked dose-dependent increases (P &lt; 0.001) in cAMP production in both GIP-R and GLP-1-R transfected cells.	Nitrogen	0-2	gastric inhibitory polypeptide receptor	Mus musculus	210-215
30028989-5	2018	N-ac(d-Ala2)GIP/GLP-1-exe significantly (P &lt; 0.001) stimulated insulin secretion from BRIN-BD11 cells and isolated mouse islets, and evoked dose-dependent increases (P &lt; 0.001) in cAMP production in both GIP-R and GLP-1-R transfected cells.	Nitrogen	0-2	glucagon-like peptide 1 receptor	Mus musculus	220-227
30365497-2	2018	Previously, the Zn2Cys6-type transcription factor Leu3/LeuB was shown to play a crucial role in regulation of BCAA biosynthesis and nitrogen metabolism in Saccharomyces cerevisiae and Aspergillus nidulans.	Nitrogen	132-140	leucine-responsive transcriptional regulator LEU3	Saccharomyces cerevisiae S288C	50-54
30365537-10	2018	The results suggest that applying 50 muM of GA3 to the development of Tifton 85 bermudagrass provides higher dry matter yield and removal of nitrogen, phosphorus, and sodium for the first crop cycle in CWs.	Nitrogen	141-149	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	44-47
30311906-4	2018	We generated a cerebellum specific knockout mouse for Srd5a3, a gene involved in the initiation of N-glycosylation.	Nitrogen	99-100	steroid 5 alpha-reductase 3	Mus musculus	54-60
30012463-5	2018	Among the potential corresponding target mRNAs for the selected mature miRNAs, seven cell growth-related target genes (e2f2, akt2, mtor, bcl-2, bim, p38alpha, and bmf) and five N-glycosylation-related target genes (neu1, b4galt3, gale, man1b1 and mgat4a) were selected by considering the effectiveness of NaBu on rCHO cell culture.	Nitrogen	43-44	mechanistic target of rapamycin kinase	Rattus norvegicus	131-135
28482115-7	2017	FLA4 functions as a soluble glycoprotein via its carboxy-proximal Fas1 domain and its normal cellular trafficking depends on N- and O-glycosylation.	Nitrogen	125-126	Fasciclin-like arabinogalactan family protein	Arabidopsis thaliana	0-4
30149019-10	2018	The N-acetylation capacity of NAT2 in the presence of SIRT1 enhancer was significantly decreased (p &lt; 0.001), conversely, the transient silencing of SIRT1 resulted in an increase of N-acetylation capacity (p &lt; 0.001).	Nitrogen	4-5	N-acetyltransferase 2	Homo sapiens	30-34
29945932-0	2018	Dopamine Transporter Dynamics of N-Substituted Benztropine Analogs with Atypical Behavioral Effects.	Nitrogen	33-34	solute carrier family 6 member 3	Homo sapiens	0-20
30082496-5	2018	Our results demonstrate that, independent of nitrogen conditions, aap2 plants allocate more nitrogen to leaves than wild-type plants.	Nitrogen	92-100	amino acid permease 2	Arabidopsis thaliana	66-70
30082496-7	2018	The aap2 plants outperformed wild-type plants with respect to growth, seed yield and carbon storage pools, and nitrogen use efficiency in both high and deficient nitrogen environments.	Nitrogen	111-119	amino acid permease 2	Arabidopsis thaliana	4-8
30082496-7	2018	The aap2 plants outperformed wild-type plants with respect to growth, seed yield and carbon storage pools, and nitrogen use efficiency in both high and deficient nitrogen environments.	Nitrogen	162-170	amino acid permease 2	Arabidopsis thaliana	4-8
30067011-7	2018	Consequently, SIM and N-siRNA synergistically increased the BMP-2/noggin ratio and resulted in an obviously higher osteogenetic effect than did simvastatin or N-siRNA alone, both in vitro and in vivo.	Nitrogen	22-23	noggin	Mus musculus	66-72
30035374-7	2018	Apart from FMO1, some cytochrome P450 monooxygenases involved in secondary metabolism catalyze N-hydroxylation reactions in plants.	Nitrogen	95-96	flavin-dependent monooxygenase 1	Arabidopsis thaliana	11-15
30029385-1	2018	In this work, a new enzymeless sensor for hydrogen peroxide (H2O2) was constructed by supporting CoFe nanoparticles on the nitrogen-doped graphene (CoFe/NGR).	Nitrogen	123-131	reticulon 4 receptor	Homo sapiens	153-156
30225070-7	2018	It was also found that the inhibition of AYR, nitrogen and COD removal induced by a higher concentration of AYR was due to the increased intracellular reactive oxygen species production, which caused the rise of oxidation-reduction potential value and decreased ammonia monooxygenase and nitrite oxidoreductase activities.	Nitrogen	46-54	thioredoxin reductase 1	Homo sapiens	296-310
28588114-6	2017	C. reinhardtii knockdown mutants for GPD2 and GPD3 showed no difference in growth but displayed significant reduction in TAG concentration compared with the wild type in response to phosphorus or nitrogen starvation.	Nitrogen	196-204	glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2	Saccharomyces cerevisiae S288C	37-41
30141651-1	2018	We present a flexible scheme to realize non-Markovian dynamics of an electronic spin qubit, using a nitrogen-vacancy center in diamond where the inherent nitrogen spin serves as a regulator of the dynamics.	Nitrogen	100-108	spindlin 1	Homo sapiens	80-84
30141651-1	2018	We present a flexible scheme to realize non-Markovian dynamics of an electronic spin qubit, using a nitrogen-vacancy center in diamond where the inherent nitrogen spin serves as a regulator of the dynamics.	Nitrogen	100-108	spindlin 1	Homo sapiens	163-167
30141651-1	2018	We present a flexible scheme to realize non-Markovian dynamics of an electronic spin qubit, using a nitrogen-vacancy center in diamond where the inherent nitrogen spin serves as a regulator of the dynamics.	Nitrogen	154-162	spindlin 1	Homo sapiens	80-84
30338036-8	2018	Indeed, genome-wide cDNA microarray and western blot analyses demonstrated higher mRNA and protein levels of hedgehog acyltransferase (HHAT), which is associated with stem maintenance in cell carcinoma by catalysing the N-palmitoylation of Hedgehog proteins, in eSAS cells than in SAS cells.	Nitrogen	22-23	hedgehog acyltransferase	Mus musculus	109-133
30338036-8	2018	Indeed, genome-wide cDNA microarray and western blot analyses demonstrated higher mRNA and protein levels of hedgehog acyltransferase (HHAT), which is associated with stem maintenance in cell carcinoma by catalysing the N-palmitoylation of Hedgehog proteins, in eSAS cells than in SAS cells.	Nitrogen	22-23	hedgehog acyltransferase	Mus musculus	135-139
30141651-1	2018	We present a flexible scheme to realize non-Markovian dynamics of an electronic spin qubit, using a nitrogen-vacancy center in diamond where the inherent nitrogen spin serves as a regulator of the dynamics.	Nitrogen	154-162	spindlin 1	Homo sapiens	163-167
30141651-2	2018	By changing the population of the nitrogen spin, we show that we can smoothly tune the non-Markovianity of the electron spin"s dynamics.	Nitrogen	34-42	spindlin 1	Homo sapiens	43-47
28588114-6	2017	C. reinhardtii knockdown mutants for GPD2 and GPD3 showed no difference in growth but displayed significant reduction in TAG concentration compared with the wild type in response to phosphorus or nitrogen starvation.	Nitrogen	196-204	glycerol-3-phosphate dehydrogenase (NAD(+)) GPD2	Saccharomyces cerevisiae S288C	46-50
30141651-2	2018	By changing the population of the nitrogen spin, we show that we can smoothly tune the non-Markovianity of the electron spin"s dynamics.	Nitrogen	34-42	spindlin 1	Homo sapiens	120-124
30114676-1	2018	The objective of this study was to reveal the physiological and molecular mechanisms of low-nitrogen (N) tolerance in transgenic plant lines containing C4 phosphoenolpyruvate carboxylase (C4-PEPC) gene.	Nitrogen	92-100	phosphoenolpyruvate carboxylase 1	Zea mays	191-195
28627074-1	2017	A transition-metal-nitrogen/carbon (TM-N/C, TM = Fe, Co, Ni, etc.)	Nitrogen	19-27	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	36-42
30182597-7	2018	Compared with normal level of nitrogen (CK), NR, GS, GOGAT, GDH activity in roots and leaves and NiR activity in roots significantly decreased under low and high nitrogen stress.	Nitrogen	162-170	glycerate dehydrogenase	Cucumis sativus	60-63
29953234-5	2018	The anti aldol product was easily isolated in pure form and then taken forward as the key precursor in the preparation of both a set of ten N-/O-alkylated anti 2-amino-1,3-diol derivatives and the syn congeners.	Nitrogen	140-142	synemin	Homo sapiens	197-200
28706275-7	2017	Furthermore, PAPPA blockage with antibody inhibited embryo implantation in vivo, mouse embryo adhesion and spreading in vitro, as well as N-fucosylation level of the endometrium in pregnant mice.	Nitrogen	138-139	pregnancy-associated plasma protein A	Mus musculus	13-18
30085738-5	2018	By controlling the spin states of nitrogen vacancy color centers in diamond, we observe slow, subexponential relaxation dynamics and identify a regime of power-law decay with disorder-dependent exponents; this behavior is modified at late times owing to many-body interactions.	Nitrogen	34-42	spindlin 1	Homo sapiens	19-23
28700931-5	2017	An Lst4 variant disrupting this feedback inhibition mechanism causes TORC1 hyperactivation and proliferation defects in cells grown on poor nitrogen sources.	Nitrogen	140-148	Lst4p	Saccharomyces cerevisiae S288C	3-7
29883121-0	2018	Hierarchically Porous N,S-Codoped Carbon-Embedded Dual Phase MnO/MnS Nanoparticles for Efficient Lithium Ion Storage.	Nitrogen	22-23	glycophorin E (MNS blood group)	Homo sapiens	65-68
29757379-6	2018	We found a highly conserved N-linked glycosylation site to be required for QSOX1 secretion from fibroblasts and other cell types.	Nitrogen	28-29	quiescin sulfhydryl oxidase 1	Homo sapiens	75-80
28744299-5	2017	Additionally, waterlogging decreased the activity of key N metabolism enzymes (nitrate reductase, glutamine, glutamate synthase, and glutamate dehydrogenase), and the most significant reduction in V3-W with a decrease of 59, 46, 35, and 26% for DH605, and 60, 53, 31, and 25 for ZD958, respectively.	Nitrogen	57-58	nitrate reductase [NADH] 1	Zea mays	79-96
30008885-9	2018	In newly diagnosed cases, the tumor to normal uptake (T/N) ratio revealed a significant positive correlation with MGMT methylation (R=0.54, P=0.009) and a marginal correlation with cell density (R=0.42, P=0.05).	Nitrogen	56-57	O-6-methylguanine-DNA methyltransferase	Homo sapiens	114-118
30019944-7	2018	The results of the interaction potential surface map analysis showed that the nitrogen and oxygen atoms have a relatively similar role in the binding of ligands to the CCR5 protein structure.	Nitrogen	78-86	C-C motif chemokine receptor 5	Homo sapiens	168-172
29656185-5	2018	Moreover, SERP1 enhanced GLP-1R N-glycosylation and increased the production of phosphorylated endothelial nitric oxide synthase (eNOS) as well as proliferation of RAOECs.	Nitrogen	32-33	glucagon-like peptide 1 receptor	Rattus norvegicus	25-31
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	vitamin D3 receptor	Capra hircus	164-182
29754009-5	2018	The aim of the present study was to examine the effects of N- and/or Ca-reduced diets on the expression of 24-hydroxylase (CYP24A1), 1-alpha-hydroxylase (CYP27B1), vitamin D receptor (VDR), retinoid X receptor alpha (RXRalpha), IGF1 receptor (IGF1R), Klotho, and fibroblast growth factor receptor 1c (FGFR1c) in kidneys of young goats.	Nitrogen	59-60	vitamin D3 receptor	Capra hircus	184-187
29486268-4	2018	The aim of this study was to demonstrate the impact of n-3 PUFA supplementation on cognitive functions, neuronal activity and neurogenesis.	Nitrogen	33-34	pumilio RNA binding family member 3	Homo sapiens	59-63
29673842-2	2018	OBJECTIVE: We aimed to evaluate the effects of an n-octanoylated ghrelin peptide on oocyte meiotic resumption and the developmental competence of mature oocytes in vitro.	Nitrogen	48-49	ghrelin and obestatin prepropeptide	Bos taurus	65-72
28489325-1	2017	L-Selectin, a cell-adhesion receptor on the surface of most leukocytes, contains seven N-glycosylation sites.	Nitrogen	87-88	selectin L	Homo sapiens	0-10
30017047-4	2018	Hence, this study aimed to investigate the effects of N addition on SMR and Q10 values in soils of native Brazilian Cerrado (NC3), and of an agricultural ecosystem (AE4) cultivated over the past 17 years.	Nitrogen	54-55	LY6/PLAUR domain containing 4	Homo sapiens	68-71
30027094-5	2018	The results showed that the expressions of HvNIA2 (nitrite reductase), HvGS2 (chloroplastic glutamine synthetase), and HvGLU2 (ferredoxin-dependent glutamate synthase) were only induced in shoots of BI-04 under low-nitrogen stress, HvGLU2 was also only induced in roots of BI-04, and HvGS2 showed a rapid response to low-nitrogen stress in the roots of BI-04.	Nitrogen	215-223	ferredoxin-dependent glutamate synthase, Fd-GOGAT	Hordeum vulgare	127-166
30027094-5	2018	The results showed that the expressions of HvNIA2 (nitrite reductase), HvGS2 (chloroplastic glutamine synthetase), and HvGLU2 (ferredoxin-dependent glutamate synthase) were only induced in shoots of BI-04 under low-nitrogen stress, HvGLU2 was also only induced in roots of BI-04, and HvGS2 showed a rapid response to low-nitrogen stress in the roots of BI-04.	Nitrogen	321-329	ferredoxin-dependent glutamate synthase, Fd-GOGAT	Hordeum vulgare	127-166
28428201-4	2017	The mycobacterial protein, dihydrolipoamide dehydrogenase (Lpd; Rv0462), the third enzyme of the pyruvate dehydrogenase (PDH) complex, facilitates Mycobacterium tuberculosis to resist host reactive nitrogen intermediates.	Nitrogen	198-206	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	Homo sapiens	59-62
29668941-0	2018	Robust, pleiotropic drug resistance 5 (Pdr5)-mediated multidrug resistance is vigorously maintained in Saccharomyces cerevisiae cells during glucose and nitrogen limitation.	Nitrogen	153-161	ATP-binding cassette multidrug transporter PDR5	Saccharomyces cerevisiae S288C	8-37
29668941-0	2018	Robust, pleiotropic drug resistance 5 (Pdr5)-mediated multidrug resistance is vigorously maintained in Saccharomyces cerevisiae cells during glucose and nitrogen limitation.	Nitrogen	153-161	ATP-binding cassette multidrug transporter PDR5	Saccharomyces cerevisiae S288C	39-43
29741757-4	2018	To identify the galectin-3-binding site, we used mass spectrometry to show that CD146 eFL has four N-glycosites, with PNGase F treatment indicating that N-glycans define the binding epitope.	Nitrogen	99-100	melanoma cell adhesion molecule	Homo sapiens	80-85
29718541-6	2018	Both participate in Nox1 trafficking, as Nox1 advances to the cell surface in two differentially N-glycosylated forms, one complex and one high mannose, in a Sar1/Stx5-dependent and -independent manner, respectively.	Nitrogen	20-21	syntaxin 5	Homo sapiens	163-167
28502432-2	2017	In the present study, a facile and sensitive fluorescent assay based on enzyme activated inner filter effect (IFE) on nitrogen-doped carbon dots (CDs) was first developed for the detection of alpha-glucosidase.	Nitrogen	118-126	sucrase-isomaltase	Homo sapiens	192-209
29718541-7	2018	Nox2 and Nox5 also can use both pathways: a glycosylation-defective mutant Nox2 is weakly recruited to the plasma membrane in a less Sar1-dependent manner; N-glycosylated Nox5 mutants reach the cell surface in part as the complex form Sar1-dependently, albeit mainly as the high-mannose form in a Sar1-independent manner.	Nitrogen	0-1	cytochrome b-245 beta chain	Homo sapiens	75-79
29233911-0	2018	N- and O-glycosylation Analysis of Human C1-inhibitor Reveals Extensive Mucin-type O-Glycosylation.	Nitrogen	0-1	serpin family G member 1	Homo sapiens	41-53
29233911-4	2018	Here, we performed for the first time an in-depth site-specific N- and O-glycosylation analysis of C1-Inh combining various mass spectrometric approaches, including C18-porous graphitized carbon (PGC)-LC-ESI-QTOF-MS/MS applying stepping-energy collision-induced dissociation (CID) and electron-transfer dissociation (ETD).	Nitrogen	64-65	serpin family G member 1	Homo sapiens	99-105
28634385-4	2017	As for the large-angle bevel structures, BCl3 + N2 gas mixtures show better characteristics, exhibiting a controllable and large etching angle range from 40  to 80  through the adjustment of the mixture ratio.	Nitrogen	48-50	BCL3 transcription coactivator	Homo sapiens	41-45
29849134-1	2018	Single nitrogen-vacancy (NV) defect centers in diamond have been exploited as single photon sources and spin qubits due to their room-temperature robust quantum light emission and long electron spin coherence times.	Nitrogen	7-15	spindlin 1	Homo sapiens	104-108
29849134-1	2018	Single nitrogen-vacancy (NV) defect centers in diamond have been exploited as single photon sources and spin qubits due to their room-temperature robust quantum light emission and long electron spin coherence times.	Nitrogen	7-15	spindlin 1	Homo sapiens	194-198
29669921-3	2018	Herein, we describe the design, synthesis, and evaluation of a collection of N-arylated benzimidazole derivatives (BIMs), one of which (BIM1) shows unparalleled (&gt;20-fold) selectivity for CLC-Ka over CLC-Kb, the two most closely related human CLC homologs.	Nitrogen	77-78	Charcot-Leyden crystal galectin	Homo sapiens	191-194
28300864-9	2017	The rare variants in the HYAL2 gene-based association included a missense variant (N357S) at a known N-glycosylation site and a nonsense variant (Q406*) that removes a glycophosphatidylinositol (GPI) anchor from the resulting protein.	Nitrogen	83-84	hyaluronidase 2	Homo sapiens	25-30
29669921-3	2018	Herein, we describe the design, synthesis, and evaluation of a collection of N-arylated benzimidazole derivatives (BIMs), one of which (BIM1) shows unparalleled (&gt;20-fold) selectivity for CLC-Ka over CLC-Kb, the two most closely related human CLC homologs.	Nitrogen	77-78	Charcot-Leyden crystal galectin	Homo sapiens	203-206
29412948-1	2018	A novel nitrogen/argon (N2/Ar) radio frequency (RF) plasma functionalized graphene nanosheet/graphene nanoribbon (GS/GNR) hybrid material (N2/Ar/GS/GNR) was developed for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA).	Nitrogen	8-16	serpin family A member 2 (gene/pseudogene)	Homo sapiens	142-151
31938367-3	2018	The results showed that in Han ethnic group, MTA1 expression was positively correlated with N staging, while the expression of MTA2 was negatively correlated with age, and the expression of MTA3 was positively correlated with gender.	Nitrogen	92-93	metastasis associated 1	Homo sapiens	45-49
29629463-1	2018	Most biological nitrogen fixation (BNF) results from the activity of the molybdenum nitrogenase (Mo-nitrogenase, Nif), an oxygen-sensitive metalloenzyme complex found in all known diazotrophs.	Nitrogen	16-24	S100 calcium binding protein A9	Homo sapiens	113-116
28868120-1	2017	OBJECTIVES: Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect comparable to that of IBMX (3-isobutyl-1-methylxanthine), a non-selective PDE inhibitor, but with differential chronotropic effect.	Nitrogen	144-145	phosphodiesterase 4D, cAMP-specific-like 1	Rattus norvegicus	190-209
29519914-1	2018	Protein synthesis, transport, and N-glycosylation are coupled at the mammalian endoplasmic reticulum by complex formation of a ribosome, the Sec61 protein-conducting channel, and oligosaccharyltransferase (OST).	Nitrogen	34-35	SEC61 translocon subunit alpha 1	Homo sapiens	141-146
28868120-1	2017	OBJECTIVES: Recently, we showed that some new synthetic compounds structurally related to cilostamide (4-(1,2-dihydro-2-oxoquinolin-6-hydroxy)- N-cyclohexyl-N-methylbutanamide), a selective phosphodiesterase 3 (PDE3) inhibitor, produce inotropic effect comparable to that of IBMX (3-isobutyl-1-methylxanthine), a non-selective PDE inhibitor, but with differential chronotropic effect.	Nitrogen	144-145	phosphodiesterase 4D, cAMP-specific-like 1	Rattus norvegicus	211-215
29502402-4	2018	Both theory and experiment show that much of the unpaired electron spin in the N1-phenylbenzotriazole anion radical is delocalized over the entire pi system of benzotriazole ring including the phenyl ring attached, but that a significant percentage of total spin is found to reside within triazole ring with much of it located on the second nitrogen (N2).	Nitrogen	341-349	spindlin 1	Homo sapiens	67-71
29502402-4	2018	Both theory and experiment show that much of the unpaired electron spin in the N1-phenylbenzotriazole anion radical is delocalized over the entire pi system of benzotriazole ring including the phenyl ring attached, but that a significant percentage of total spin is found to reside within triazole ring with much of it located on the second nitrogen (N2).	Nitrogen	351-353	spindlin 1	Homo sapiens	67-71
28613381-1	2017	The relative quantitative real-time expression of two expressed sequence tags (ESTs) codifying for key enzymes in nitrogen metabolism in maize, nitrate reductase (ZmNR), and glutamine synthetase (ZmGln1-3) was performed for genotypes inoculated with Azospirillum brasilense.	Nitrogen	114-122	nitrate reductase [NADH] 1	Zea mays	144-161
29502402-5	2018	With the N1-phenylcyclooctatetraenotriazole anion radical, the majority of spin is localized over the pi system of the COT ring, however a relatively small amount of total spin, found within the triazole moiety, is largely concentrated on two of the nitrogens (N1 and N3) within the ring.	Nitrogen	250-259	spindlin 1	Homo sapiens	75-79
29508999-3	2018	By taking advantage of the synergetic effect of N-G and FePc nanocomposites, the N-G/FePc sensor displays excellent electrocatalytic activity toward NO with a high sensitivity of 0.21 muA muM-1 cm-2 and a low detection limit of 180 nmol L-1.	Nitrogen	48-49	PWWP domain containing 3A, DNA repair factor	Homo sapiens	188-193
28534482-4	2017	We identified Fbs1 variants through mutagenesis and plasmid display selection, which possess higher affinity and improved recovery of complex N-glycomolecules.	Nitrogen	142-143	fibrosin	Homo sapiens	14-18
28515731-6	2017	Consistently, metabolomic profiling revealed that CDF3 evokes changes in the primary metabolism triggering enhanced nitrogen assimilation, and disclosed that the amount of some protective metabolites including sucrose, GABA and asparagine were higher in vegetative tissues of CDF3 overexpressing plants.	Nitrogen	116-124	cycling DOF factor 3	Arabidopsis thaliana	50-54
29519126-2	2018	The design of new molecules (DA1-DA12) was based on the bridge-ring structures that could be formed via Diels-Alder (DA) reaction of selected nitrogen-rich dienes and tetranitroethylene dienophile.	Nitrogen	142-150	immunoglobulin heavy diversity 4-11 (non-functional)	Homo sapiens	29-32
29323465-3	2018	Time course induction of ER stress, using tunicamycin (TM), shows a group of genes such as Chop, Trb3, Sqstm1, Grp78, and Herpud1 respond rapidly to TM inhibition of N-glycosylation, while others such as Atf5, Odz4, and Birc5 exhibits a delayed response.	Nitrogen	166-167	endoplasmic reticulum chaperone BiP	Cricetulus griseus	111-116
29599842-5	2018	In addition, administration of combined simvastatin and kallistatin decreased the blood urea nitrogen and serum creatinine levels in the patients.	Nitrogen	93-101	serpin family A member 4	Homo sapiens	56-67
28303575-2	2017	Human monocyte populations express Dectin-1 isoforms A and B, which differ by the presence of a stalk region and its N-linked glycosylation site.	Nitrogen	117-118	C-type lectin domain containing 7A	Homo sapiens	35-43
28303575-11	2017	We show here that n-glycosylation of Dectin-1 is crucial for its cell surface expression and consequently signal transduction.	Nitrogen	18-19	C-type lectin domain containing 7A	Homo sapiens	37-45
29106682-7	2018	Molecular docking analysis revealed that key hydrogen bonds were formed by nitrogen atoms of the imidazole bond with Val440 of CFTR and Ala697 of the SLC26 family.	Nitrogen	75-83	cystic fibrosis transmembrane conductance regulator	Mus musculus	127-131
28256015-1	2017	The synthesis of a class of electron-rich amino-functionalized beta-diketiminato (N-nacnac) ligands is reported, with two synthetic methodologies having been developed for systems bearing backbone NMe2 or NEt2 groups and a range of N-bound aryl substituents.	Nitrogen	82-83	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	197-201
29402915-7	2018	Quantitative mass spectrometry and mutagenesis demonstrated that N-linked glycosylation of at least 4 residues of cubilin protein was required for its surface targeting.	Nitrogen	65-66	cubilin	Homo sapiens	114-121
28032637-0	2017	Nitrogen Limitation Adaptation (NLA) is involved in source-to-sink remobilization of nitrate by mediating the degradation of NRT1.7 in Arabidopsis.	Nitrogen	0-8	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	32-35
29481176-3	2018	We utilize this method to explore spin dephasing effects in an impurity-rich sample beyond the limit of phonon-induced decoherence: Employing Ramsey and Hahn-echo techniques at temperatures down to 40 mK we identify resonant coupling to a substitutional nitrogen spin bath as limiting decoherence source for the electron spin.	Nitrogen	254-262	spindlin 1	Homo sapiens	34-38
28032637-3	2017	The nitrogen limitation adaptation (nla) mutant is hypersensitive to N limitation.	Nitrogen	4-12	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	36-39
28275852-1	2017	KEY MESSAGE: DELLA proteins positively regulate nitrogen deficiency-induced anthocyanin accumulation through directly interaction with PAP1 to enhance its transcriptional activity on anthocyanin biosynthetic gene expressions.	Nitrogen	48-56	phosphatidic acid phosphatase 1	Arabidopsis thaliana	135-139
29552444-4	2018	Sequencing of genomic DNA revealed a heterozygous COL1A1 mutation (c.671G&gt;A, p.Gly224Asp) that affected the N-anchor domain of the alpha 1 chain of collagen type I. Ultrastructural analysis of a skin biopsy specimen revealed thin collagen fibers with irregular alignment of collagen fibers.	Nitrogen	23-24	collagen type I alpha 1 chain	Homo sapiens	50-56
28275852-9	2017	Taken together, this study suggests that DELLAs are necessary regulators for nitrogen deficiency-induced anthocyanin accumulation through interaction with PAP1 and enhancement of PAP1"s transcriptional activity on its target genes.	Nitrogen	77-85	phosphatidic acid phosphatase 1	Arabidopsis thaliana	155-159
29197127-3	2018	However, the metabolic utilisation of preferred carbon and nitrogen sources, encountered in a host niche-dependent manner, is known as carbon catabolite and nitrogen catabolite repression (CCR, NCR), and has been shown to be important for virulence.	Nitrogen	157-165	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	194-197
29128700-2	2018	Embryo freezing in liquid nitrogen (LN2) at -196  C has traditionally been the method of choice for archiving mouse lines.	Nitrogen	26-34	NZ lupus nephritis 2	Mus musculus	36-39
30065132-0	2018	Effects of recirculation and separation times on nitrogen removal in baffled membrane bioreactor (B-MBR).	Nitrogen	49-57	translocator protein	Homo sapiens	100-103
29932112-2	2018	We previously reported that N-glycosylation acts as a regulator of the localization and intermixing of Panx1 and Panx3, but its effects on Panx2 are currently unknown.	Nitrogen	28-29	pannexin 1	Homo sapiens	103-108
29932112-2	2018	We previously reported that N-glycosylation acts as a regulator of the localization and intermixing of Panx1 and Panx3, but its effects on Panx2 are currently unknown.	Nitrogen	28-29	pannexin 3	Homo sapiens	113-118
29362985-6	2018	The growth of tumors in the treated groups was assessed by histological changes and the up/down expression of p53, cdkn1, cdk2, e-cdh, and n-cdh genes in different parts of GI tract.	Nitrogen	22-23	cyclin dependent kinase 2	Rattus norvegicus	122-126
28275852-9	2017	Taken together, this study suggests that DELLAs are necessary regulators for nitrogen deficiency-induced anthocyanin accumulation through interaction with PAP1 and enhancement of PAP1"s transcriptional activity on its target genes.	Nitrogen	77-85	phosphatidic acid phosphatase 1	Arabidopsis thaliana	179-183
28137749-1	2017	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein syntaxin-1 adopts a closed conformation when bound to Munc18-1, preventing binding to synaptobrevin-2 and SNAP-25 to form the ternary SNARE complex.	Nitrogen	12-13	synaptosome associated protein 25	Homo sapiens	196-203
29686055-4	2018	Mutation of RAPTOR1B resulted in a strong reduction of TOR kinase activity, leading to massive changes in central carbon and nitrogen metabolism, accumulation of excess starch, and induction of autophagy.	Nitrogen	125-133	Regulatory-associated protein of TOR 1	Arabidopsis thaliana	12-20
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	carbonic anhydrase 1	Homo sapiens	225-228
29247860-0	2018	Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation.	Nitrogen	30-31	lysine demethylase 1A	Homo sapiens	135-139
29247860-2	2018	Clinical candidates are N-substituted derivatives of the dual LSD1-/monoamine oxidase-inhibitor tranylcypromine (2-PCPA) with a basic amine function in the N-substituent.	Nitrogen	24-25	lysine demethylase 1A	Homo sapiens	62-66
29247860-5	2018	Here, we show that N-substituted 2-PCPA derivatives without a basic function or even a polar group are still potent inhibitors of LSD1 in vitro and effectively inhibit colony formation of leukemic cells in culture.	Nitrogen	19-20	lysine demethylase 1A	Homo sapiens	130-134
29909694-10	2018	Furthermore, pathway enrichment analysis showed that some DEGs were related to primary immunodeficiency (e.g., CD4, CD3D and CD40LG), complement and coagulation cascades (e.g., C2, C1QB and C7) and nitrogen metabolism (e.g., CA1, CA12 and CA2).	Nitrogen	198-206	carbonic anhydrase 2	Homo sapiens	239-242
28215986-0	2017	The beta4GalT1 affects the fibroblast-like synoviocytes invasion in rheumatoid arthritis by modifying N-linked glycosylation of CXCR3.	Nitrogen	102-103	chemokine (C-X-C motif) receptor 3	Mus musculus	128-133
29656199-4	2018	The preferred binding modes of selected compounds for the sigma1R are predicted by modeling studies, and the nature of substituents on the aromatic ring and the nitrogen atom of the bicyclic skeleton appears to affect the preferred binding orientation of sigma1R-preferring ligands.	Nitrogen	161-169	sigma non-opioid intracellular receptor 1	Homo sapiens	58-65
29656199-4	2018	The preferred binding modes of selected compounds for the sigma1R are predicted by modeling studies, and the nature of substituents on the aromatic ring and the nitrogen atom of the bicyclic skeleton appears to affect the preferred binding orientation of sigma1R-preferring ligands.	Nitrogen	161-169	sigma non-opioid intracellular receptor 1	Homo sapiens	255-262
29155413-2	2018	In this contribution, we proposed a simple green liquid nitrogen gas exfoliation strategy for preparation of porous monolayer nanosheets (BN-1).	Nitrogen	56-64	C-C motif chemokine receptor 6	Homo sapiens	138-142
29149994-0	2018	A novel fluorescence biosensor for sensitivity detection of tyrosinase and acid phosphatase based on nitrogen-doped graphene quantum dots.	Nitrogen	101-109	tyrosinase	Homo sapiens	60-70
29149994-1	2018	In this paper, we developed a sensitive fluorescence biosensor for tyrosinase (TYR) and acid phosphatase (ACP) activity detection based on nitrogen-doped graphene quantum dots (N-GQDs).	Nitrogen	139-147	tyrosinase	Homo sapiens	67-77
29717117-0	2018	N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.	Nitrogen	0-1	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	25-30
29717117-0	2018	N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.	Nitrogen	0-1	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	43-48
28215986-5	2017	The N-glycosylation of CXCR3 was detected by mass spectrometry and western-blot.	Nitrogen	4-5	chemokine (C-X-C motif) receptor 3	Mus musculus	23-28
29717117-7	2018	Instead, it relied on the inhibition of N-glycosylation of the mouse TRAIL receptor (mTRAIL-R).	Nitrogen	40-41	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	69-74
29149994-1	2018	In this paper, we developed a sensitive fluorescence biosensor for tyrosinase (TYR) and acid phosphatase (ACP) activity detection based on nitrogen-doped graphene quantum dots (N-GQDs).	Nitrogen	139-147	tyrosinase	Homo sapiens	79-82
28215986-10	2017	CXCR3 was N-glycosylated and its glycosylation regulated by beta4GalT1.	Nitrogen	10-11	chemokine (C-X-C motif) receptor 3	Mus musculus	0-5
29607936-9	2018	Moreover, we found that STT3B-dependent posttranslational N-glycosylation at N98 residue occurred in G101S TTR but not in other TTR variants, possibly due to amino acid alterations that increase N-glycosylation preference or accelerate rigid structure formation susceptible to N-glycosylation.	Nitrogen	58-59	transthyretin	Homo sapiens	107-110
29717117-9	2018	Remarkably, reconstitution of mTRAIL-R-deficient cells with a version of mTRAIL-R mutated for the three N-glycosylation sites identified in its ectodomain confirmed higher sensitivity to TRAIL-induced apoptosis.	Nitrogen	104-105	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	31-36
29717117-10	2018	Together, our results demonstrate that inhibition of N-glycosylation of mTRAIL-R, and not ER stress induction, sensitizes mouse cells to TRAIL-induced apoptosis.	Nitrogen	53-54	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	73-78
28215986-12	2017	N-glycosylation of CXCR3 influences the ligand-receptor interaction between CXCR3 and CXCL10.	Nitrogen	0-1	chemokine (C-X-C motif) receptor 3	Mus musculus	19-24
28215986-12	2017	N-glycosylation of CXCR3 influences the ligand-receptor interaction between CXCR3 and CXCL10.	Nitrogen	0-1	chemokine (C-X-C motif) receptor 3	Mus musculus	76-81
29452367-7	2018	This variant eliminated a conserved N-glycosylation sequon at Asn160 in POFUT1 and profoundly decreased POFUT1 activity in patient fibroblasts compared to control fibroblasts.	Nitrogen	36-37	protein O-fucosyltransferase 1	Homo sapiens	72-78
29452367-7	2018	This variant eliminated a conserved N-glycosylation sequon at Asn160 in POFUT1 and profoundly decreased POFUT1 activity in patient fibroblasts compared to control fibroblasts.	Nitrogen	36-37	protein O-fucosyltransferase 1	Homo sapiens	104-110
29197730-2	2018	Main emphasis was the introduction of several N-containing functional groups such as amines, amides and oximes and their screening for cytotoxic activity employing several human tumor cell lines using SRB assays.	Nitrogen	46-47	chaperonin containing TCP1 subunit 4	Homo sapiens	201-204
28661051-2	2018	They are encoded by four conserved paralogous genes, and their vertebrate orthologs have positionally conserved N-glycosylation sequons within the second extracellular loop, EL2, of the a subunit membrane domain.	Nitrogen	112-113	spectrin alpha, erythrocytic 1	Homo sapiens	174-177
29289724-9	2018	CHS3 a major chitin synthase gene was also found to be upregulated, and the transcript abundance of key genes of central nitrogen metabolism, GLN1, GLT1, GDH1 and GDH2 in mutant  ecm33 were also altered.	Nitrogen	121-129	chitin synthase CHS3	Saccharomyces cerevisiae S288C	0-4
28230162-3	2017	In this study, we explored the effects of N-acetylated Proline-Glycine-Proline (Ac-PGP), a degradation product of collagen, on hEPC-mediated cutaneous wound healing and neovascularization.	Nitrogen	42-43	phosphoglycolate phosphatase	Homo sapiens	83-86
28230162-3	2017	In this study, we explored the effects of N-acetylated Proline-Glycine-Proline (Ac-PGP), a degradation product of collagen, on hEPC-mediated cutaneous wound healing and neovascularization.	Nitrogen	42-43	hepcidin antimicrobial peptide	Homo sapiens	127-131
28286582-2	2017	Different concentrations of functional groups do not affect the size (3-5 nm) of Fe particles in the fresh catalysts but iron (carbide) supported on N-enriched CMK-3 and a support with a lower concentration of functional groups show higher catalytic activity under industrially relevant FTO conditions (340  C, 10 bar, H2/CO=2) compared to a support with an O-enriched surface.	Nitrogen	149-150	complement C2	Homo sapiens	322-326
27340756-3	2017	The effect of some factors on beta-glucosidase production was studied including: Initial pH, medium composition, concentration of carbon and nitrogen sources, and particle size of raw substrates.	Nitrogen	141-149	4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1a, chloroplastic	Triticum aestivum	30-46
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	0-8	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	223-227
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	90-98	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	223-227
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	148-156	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	223-227
28007891-1	2017	Nitrogen catabolite repression (NCR), the ability of Saccharomyces cerevisiae to use good nitrogen sources in preference to poor ones, derives from nitrogen-responsive regulation of the GATA family transcription activators Gln3 and Gat1 In nitrogen-replete conditions, the GATA factors are cytoplasmic and NCR-sensitive transcription minimal.	Nitrogen	148-156	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	223-227
28007891-2	2017	When only poor nitrogen sources are available, Gln3 is nuclear, dramatically increasing GATA factor-mediated transcription.	Nitrogen	15-23	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	47-51
27748203-6	2017	Moreover, N-NS treatment reduced (P &lt; 0 05) AST and ALT levels, and prevented histopathological changes caused by the parasite.	Nitrogen	10-11	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	47-50
27748203-6	2017	Moreover, N-NS treatment reduced (P &lt; 0 05) AST and ALT levels, and prevented histopathological changes caused by the parasite.	Nitrogen	10-11	glutamic pyruvic transaminase, soluble	Mus musculus	55-58
27748203-6	2017	Moreover, N-NS treatment reduced (P &lt; 0 05) AST and ALT levels, and prevented histopathological changes caused by the parasite.	Nitrogen	12-14	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	47-50
27748203-6	2017	Moreover, N-NS treatment reduced (P &lt; 0 05) AST and ALT levels, and prevented histopathological changes caused by the parasite.	Nitrogen	12-14	glutamic pyruvic transaminase, soluble	Mus musculus	55-58
27951492-1	2017	Glutamine synthetase (GS), a key enzyme in plant nitrogen metabolism, is encoded by a small family of highly homologous nuclear genes that produce cytosolic (GS1) and plastidic (GS2) isoforms.	Nitrogen	49-57	LOC11405318	Medicago truncatula	0-20
27659270-7	2017	The allocation results showed that approximately 90% of total nitrogen (TN) load should be reduced in the 56 pollution sources around the Bohai Sea; of these values, roughly 85% of the reduction could come from 10 pollution sources.	Nitrogen	62-70	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	144-147
28011762-2	2017	Cytosolic IDH1 converts isocitrate to alpha-ketoglutarate (alpha-KG), a key metabolite regulating nitrogen homeostasis in catabolic pathways.	Nitrogen	98-106	isocitrate dehydrogenase 1 (NADP+), soluble	Mus musculus	10-14
28149202-10	2016	In particular, the altered abundance of kynureninase (KYNU) and HAL (histidine ammonia-lyase) involved in protein metabolic function, integrated with the changes of serum levels of blood urea nitrogen (BUN) and glucose (GLU), suggest that overgrazing triggers a shift in energy resources from carbohydrates to proteins, causing poorer nitrogen utilization efficiency.	Nitrogen	192-200	kynureninase	Ovis aries	54-58
28149202-10	2016	In particular, the altered abundance of kynureninase (KYNU) and HAL (histidine ammonia-lyase) involved in protein metabolic function, integrated with the changes of serum levels of blood urea nitrogen (BUN) and glucose (GLU), suggest that overgrazing triggers a shift in energy resources from carbohydrates to proteins, causing poorer nitrogen utilization efficiency.	Nitrogen	335-343	kynureninase	Ovis aries	54-58
27924923-1	2016	Phosphoenolpyruvate carboxylase (PEPC) plays an important role in assimilating atmospheric CO2 during C4 and crassulacean acid metabolism photosynthesis, and also participates in various non-photosynthetic processes, including fruit ripening, stomatal opening, supporting carbon-nitrogen interactions, seed formation and germination, and regulation of plant tolerance to stresses.	Nitrogen	279-287	phosphoenolpyruvate carboxylase, housekeeping isozyme	Glycine max	0-31
27924923-1	2016	Phosphoenolpyruvate carboxylase (PEPC) plays an important role in assimilating atmospheric CO2 during C4 and crassulacean acid metabolism photosynthesis, and also participates in various non-photosynthetic processes, including fruit ripening, stomatal opening, supporting carbon-nitrogen interactions, seed formation and germination, and regulation of plant tolerance to stresses.	Nitrogen	279-287	phosphoenolpyruvate carboxylase, housekeeping isozyme	Glycine max	33-37
27917827-2	2016	As a rare occurrence, the N14 Fab is N-glycosylated at Asn26L at the onset of the VL1 antigen-binding loop, with the alpha-1-6 core fucosylated complex glycan facing out of the L1 complementarity-determining region.	Nitrogen	26-27	FA complementation group B	Homo sapiens	30-33
27917827-2	2016	As a rare occurrence, the N14 Fab is N-glycosylated at Asn26L at the onset of the VL1 antigen-binding loop, with the alpha-1-6 core fucosylated complex glycan facing out of the L1 complementarity-determining region.	Nitrogen	26-27	adrenoceptor alpha 1D	Homo sapiens	117-126
27994690-1	2016	68Ga-Prostate specific membrane antigen- N,N"-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid- positron emission tomography/computed tomography or 68 Ga- HBED-CC-PSMA PET/CT, popularly known as PSMA PET/CT, is able to detect a small volume of recurrent prostate carcinoma (PC) when there is a prostate specific antigen (PSA) rise on follow-up after prostatectomy or other definitive treatment for PC.	Nitrogen	41-42	kallikrein related peptidase 3	Homo sapiens	317-342
27994690-1	2016	68Ga-Prostate specific membrane antigen- N,N"-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N"-diacetic acid- positron emission tomography/computed tomography or 68 Ga- HBED-CC-PSMA PET/CT, popularly known as PSMA PET/CT, is able to detect a small volume of recurrent prostate carcinoma (PC) when there is a prostate specific antigen (PSA) rise on follow-up after prostatectomy or other definitive treatment for PC.	Nitrogen	41-42	kallikrein related peptidase 3	Homo sapiens	344-347
27744113-4	2016	Here, we describe the characterization of Hsero1941, a GH3 beta-N-acetylglucosaminidase from the endophytic nitrogen-fixing bacterium Herbaspirillum seropedicae SmR1.	Nitrogen	108-116	HSERO_RS09685	Herbaspirillum seropedicae SmR1	42-51
27887569-3	2016	Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, inhibits the expression of receptor activator of nuclear factor kappa-B ligand (RANKL) on osteoblasts to inhibit osteoclastogenesis.	Nitrogen	24-32	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	87-138
27887569-3	2016	Zoledronic acid (ZA), a nitrogen-containing bisphosphonate, inhibits the expression of receptor activator of nuclear factor kappa-B ligand (RANKL) on osteoblasts to inhibit osteoclastogenesis.	Nitrogen	24-32	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	140-145
27869218-1	2016	Cluster of differentiation 147 (CD147), also known as extracellular matrix metalloproteinase inducer, is a transmembrane glycoprotein that mediates oncogenic processes partly through N-glycosylation modifications.	Nitrogen	183-184	basigin (Ok blood group)	Homo sapiens	54-100
27343988-3	2016	A previous study suggested that N-glycosylation is required for the maintenance of long-term potentiation in hippocampal CA1 neurons.	Nitrogen	32-33	carbonic anhydrase 1	Mus musculus	121-124
27739923-6	2016	Tracing experiments with 15N showed that the relative nitrogen remobilization from vegetative organs to seeds in gln1;2 was just as efficient as in the Wt plants.	Nitrogen	54-62	hypothetical protein	Arabidopsis thaliana	113-119
27739923-7	2016	This was the case although the total quantity of nitrogen in gln1;2 was significantly lower compared to that in the Wt.	Nitrogen	49-57	hypothetical protein	Arabidopsis thaliana	61-67
27739923-8	2016	We conclude that the functions of shoot Gln1;2 are primarily associated with internal N signaling for establishment of seed yield capacity rather than with nitrogen remobilization.	Nitrogen	86-87	hypothetical protein	Arabidopsis thaliana	40-46
27739923-8	2016	We conclude that the functions of shoot Gln1;2 are primarily associated with internal N signaling for establishment of seed yield capacity rather than with nitrogen remobilization.	Nitrogen	156-164	hypothetical protein	Arabidopsis thaliana	40-46
30023485-9	2016	Our models and binding data suggest that the aromatic cages of Cbx7/Cbx4 can accommodate larger alkyl groups such as diisobutyl substitution on the lysine nitrogen.	Nitrogen	155-163	chromobox 7	Homo sapiens	63-67
30023485-9	2016	Our models and binding data suggest that the aromatic cages of Cbx7/Cbx4 can accommodate larger alkyl groups such as diisobutyl substitution on the lysine nitrogen.	Nitrogen	155-163	chromobox 4	Homo sapiens	68-72
27578781-6	2016	Our data reveal that N-glycosylation of the Scw ligand boosts BMP signaling both in cell culture and in the embryo.	Nitrogen	21-22	bone morphogenetic protein 1	Homo sapiens	62-65
27644110-4	2016	We distributed chemically prepared nitrogen-doped few-layer graphene (N-FLG) sheets on Cu substrates to create island structures.	Nitrogen	35-43	filaggrin	Homo sapiens	72-75
27644110-4	2016	We distributed chemically prepared nitrogen-doped few-layer graphene (N-FLG) sheets on Cu substrates to create island structures.	Nitrogen	70-71	filaggrin	Homo sapiens	72-75
27546880-9	2016	Interestingly, the outbred strains CD-1 and Swiss Webster displayed considerably larger interindividual variation than inbred strains BALB/c and CD57BL/6, suggesting a strong hereditable component of the observed plasma N-glycome.	Nitrogen	220-221	CD1 antigen complex	Mus musculus	35-39
27056577-3	2016	An amber mutation in the DAL81 gene, which codes for a positive regulator of multiple nitrogen degradation pathways, was found in the AY77 strain.	Nitrogen	86-94	Dal81p	Saccharomyces cerevisiae S288C	25-30
27428168-4	2016	Although a modest increase in the CLint value for DTIC N-demethylation was observed for the CYP1A2 D348N variant relative to the wild type, the CLint for the F186L variant was reduced and the I386F, R431W, and R456H variants all showed loss of catalytic function.	Nitrogen	55-56	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	92-98
27428168-5	2016	CONCLUSION: Comparison of the kinetic data for DTIC N-demethylation and 7-ethoxyresorufin O-deethylation indicated that alterations in the kinetic parameters (Km, Vmax, CLint) observed with each of the CYP1A1 and CYP1A2 polymorphic variants were substrate dependent.	Nitrogen	2-3	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	202-208
27428168-5	2016	CONCLUSION: Comparison of the kinetic data for DTIC N-demethylation and 7-ethoxyresorufin O-deethylation indicated that alterations in the kinetic parameters (Km, Vmax, CLint) observed with each of the CYP1A1 and CYP1A2 polymorphic variants were substrate dependent.	Nitrogen	2-3	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	213-219
29537275-7	2018	The performance of p-NiFe2O4/n-Fe2O3 composites in PEC water oxidation was further enhanced by their deposition over 3D-NSP substrate.	Nitrogen	12-13	sperm antigen with calponin homology and coiled-coil domains 1	Homo sapiens	120-123
27519409-9	2016	Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris.	Nitrogen	188-196	malate dehydrogenase MDH2	Saccharomyces cerevisiae S288C	73-77
29537275-8	2018	The highest photocurrent density of 2.1 mA/cm2 at 1.23 VRHE was obtained for the 1:1 molar ratio p-NiFe2O4/n-Fe2O3 composite on NSP (NF1-NSP), which was 3.3 times more photocurrent density than pure hematite.	Nitrogen	22-23	sperm antigen with calponin homology and coiled-coil domains 1	Homo sapiens	128-131
29537275-8	2018	The highest photocurrent density of 2.1 mA/cm2 at 1.23 VRHE was obtained for the 1:1 molar ratio p-NiFe2O4/n-Fe2O3 composite on NSP (NF1-NSP), which was 3.3 times more photocurrent density than pure hematite.	Nitrogen	22-23	sperm antigen with calponin homology and coiled-coil domains 1	Homo sapiens	133-140
29562594-3	2018	Fc-fused capillary morphogenesis protein 2 (CMG2-Fc) containing one N-glycosylation site on the Fc domain, produced in Nicotiana benthamiana whole plants, served as a model protein.	Nitrogen	68-69	ANTXR cell adhesion molecule 2	Homo sapiens	44-48
29540771-3	2018	Our results showed that nitrogen insoluble in cold or hot water from urea-formaldehyde fertilizers were mainly affected by urea: formaldehyde molar ratios.	Nitrogen	24-32	alcohol dehydrogenase iron containing 1	Homo sapiens	54-57
28648748-5	2018	Optimum performance was achieved at an average strain rate magnitude of 12.7s-1 yielding a DO concentration of 4mgL-1 which have resulted in 74% conversion of ammonia nitrogen.	Nitrogen	167-175	LLGL scribble cell polarity complex component 1	Homo sapiens	112-117
29273704-8	2017	Consistent with this notion we show that nitrogen starvation, which promotes autophagy by deactivating Tor1, results in decreased CLS if FUS3 is deleted.	Nitrogen	41-49	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	103-107
29502530-10	2017	Trends were seen for improved grip strength and a reduction in C-Reactive Protein (CRP), Angiotensin II to Angiotensin 1-7 ratio and Interleukin-10, with no change in DNA n-methylation.	Nitrogen	3-4	interleukin 10	Homo sapiens	133-147
29242833-3	2017	However, a C. albicans put3 null mutant cannot grow on proline, suggesting that as in S. cerevisiae, C. albicans Put3 (CaPut3) is required for proline catabolism, and because the C. albicans put3 null mutant grew efficiently on glutamate as the sole carbon or nitrogen source, it appears that CaPut3 also regulates the early genes of the pathway.	Nitrogen	260-268	Put3p	Saccharomyces cerevisiae S288C	113-117
29242833-5	2017	CaPut3 directs proline degradation even in the presence of a good nitrogen source such as ammonia, which contrasts with S. cerevisiae Put3 (ScPut3)-regulated proline catabolism, which only occurs in the absence of a rich nitrogen source.	Nitrogen	66-74	Put3p	Saccharomyces cerevisiae S288C	2-6
29080272-1	2018	Nitrogen-containing bisphosphonates (N-BPs) have been used widely to treat various bone diseases by inhibiting the key enzyme farnesyl pyrophosphate synthase (FPPS) in the mevalonate pathway.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	126-157
29080272-1	2018	Nitrogen-containing bisphosphonates (N-BPs) have been used widely to treat various bone diseases by inhibiting the key enzyme farnesyl pyrophosphate synthase (FPPS) in the mevalonate pathway.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	159-163
27519409-9	2016	Mxr1p binds to Mxr1p response elements present in the promoters of AAT2, MDH2, and GLN1 We conclude that Mxr1p is essential for utilization of amino acids as the sole source of carbon and nitrogen, and it is a global regulator of multiple metabolic pathways in P. pastoris.	Nitrogen	188-196	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	83-87
29242833-10	2017	We show that the Put3 transcription factor allows the pathogen to completely degrade proline to usable nitrogen and carbon by evading regulatory restrictions imposed on its S. cerevisiae ortholog, which mandates conditional use of proline only as a nitrogen source in the baker"s yeast.	Nitrogen	103-111	Put3p	Saccharomyces cerevisiae S288C	17-21
29242833-10	2017	We show that the Put3 transcription factor allows the pathogen to completely degrade proline to usable nitrogen and carbon by evading regulatory restrictions imposed on its S. cerevisiae ortholog, which mandates conditional use of proline only as a nitrogen source in the baker"s yeast.	Nitrogen	249-257	Put3p	Saccharomyces cerevisiae S288C	17-21
27126996-8	2016	In line with this, CP-d/n-ATF5-S1 synergistically enhanced tumor cell apoptosis induced by the BH3-mimetic ABT263 and the death ligand TRAIL.	Nitrogen	1-2	carboxypeptidase D	Homo sapiens	19-23
29215008-5	2017	Conversely, N-acetyl-rich HS is rarely internalized and accumulates Frzb, a secreted Wnt antagonist.	Nitrogen	12-13	frzb	Xenopus laevis	68-72
29405629-4	2018	In this study, we propose a topological structure of DPY19L3 by in silico analysis and experimental methods such as redox-sensitive luciferase assay and introduction of N-glycosylation sites, suggesting that DPY19L3 comprises 11 transmembrane regions and two re-entrant loops with the N- and C-terminal ends facing the cytoplasm and ER lumen, respectively.	Nitrogen	169-170	dpy-19 like C-mannosyltransferase 3	Homo sapiens	53-60
29405629-4	2018	In this study, we propose a topological structure of DPY19L3 by in silico analysis and experimental methods such as redox-sensitive luciferase assay and introduction of N-glycosylation sites, suggesting that DPY19L3 comprises 11 transmembrane regions and two re-entrant loops with the N- and C-terminal ends facing the cytoplasm and ER lumen, respectively.	Nitrogen	169-170	dpy-19 like C-mannosyltransferase 3	Homo sapiens	208-215
29405629-5	2018	Furthermore, DPY19L3 has four predicted N-glycosylation sites, and we have demonstrated that DPY19L3 is N-glycosylated at Asn118 and Asn704 but not Asn319 and Asn439 , supporting our topological model.	Nitrogen	40-41	dpy-19 like C-mannosyltransferase 3	Homo sapiens	13-20
29405629-5	2018	Furthermore, DPY19L3 has four predicted N-glycosylation sites, and we have demonstrated that DPY19L3 is N-glycosylated at Asn118 and Asn704 but not Asn319 and Asn439 , supporting our topological model.	Nitrogen	104-105	dpy-19 like C-mannosyltransferase 3	Homo sapiens	13-20
29058431-3	2017	Photoextrusion of dinitrogen from these intermediates enables completely stereoselective formation of all C3a-C3a" and C3a-C7" carbon-carbon bonds and all the associated quaternary stereogenic centers.	Nitrogen	18-28	complement C3	Homo sapiens	106-109
27126996-10	2016	Finally, the combination treatment of CP-d/n-ATF5-S1 and ABT263 significantly reduced tumor growth in vivo more efficiently than each reagent on its own.	Nitrogen	2-3	carboxypeptidase D	Homo sapiens	38-42
29058431-3	2017	Photoextrusion of dinitrogen from these intermediates enables completely stereoselective formation of all C3a-C3a" and C3a-C7" carbon-carbon bonds and all the associated quaternary stereogenic centers.	Nitrogen	18-28	complement C3	Homo sapiens	110-113
29058431-3	2017	Photoextrusion of dinitrogen from these intermediates enables completely stereoselective formation of all C3a-C3a" and C3a-C7" carbon-carbon bonds and all the associated quaternary stereogenic centers.	Nitrogen	18-28	complement C3	Homo sapiens	110-113
29405629-5	2018	Furthermore, DPY19L3 has four predicted N-glycosylation sites, and we have demonstrated that DPY19L3 is N-glycosylated at Asn118 and Asn704 but not Asn319 and Asn439 , supporting our topological model.	Nitrogen	104-105	dpy-19 like C-mannosyltransferase 3	Homo sapiens	93-100
29405629-6	2018	By mass spectrometry, we measured the C-mannosyltransferase activity of N-glycosylation-defective mutants of DPY19L3 and isoform2, a splice variant, which lacks the C-terminal luminal region of DPY19L3.	Nitrogen	72-73	dpy-19 like C-mannosyltransferase 3	Homo sapiens	109-116
29405629-6	2018	By mass spectrometry, we measured the C-mannosyltransferase activity of N-glycosylation-defective mutants of DPY19L3 and isoform2, a splice variant, which lacks the C-terminal luminal region of DPY19L3.	Nitrogen	72-73	dpy-19 like C-mannosyltransferase 3	Homo sapiens	194-201
29405629-7	2018	Isoform2 does not possess C-mannosyltransferase activity, indicating the importance of the C-terminal region; however, N-glycosylations of DPY19L3 do not have any roles for its enzymatic activity.	Nitrogen	119-120	dpy-19 like C-mannosyltransferase 3	Homo sapiens	139-146
27541867-1	2016	A novel class of dibenzo-fused 1,9-diaza-9a-boraphenalenes featuring zigzag edges with a nitrogen-boron-nitrogen bonding pattern named NBN-dibenzophenalenes (NBN-DBPs) has been synthesized.	Nitrogen	89-97	nibrin	Homo sapiens	135-138
29228327-1	2018	Methylation of the adenosine base at the nitrogen-6 position (m6A) is the most prevalent internal posttranscriptional modification of mRNAs in many eukaryotes.	Nitrogen	41-49	glycoprotein M6A	Homo sapiens	62-65
29137785-9	2018	The increase in the permeability of the gases was as follows: PCH4 (38%) &lt;PN2 (58%) &lt;PCO2 (88%) &lt;PO2 (98%) Adding silica nanoparticles into the PE matrix, improved the separation performance of carbon dioxide/methane and carbon dioxide/nitrogen gases.	Nitrogen	245-253	tRNA splicing endonuclease subunit 54	Homo sapiens	62-66
29426894-3	2018	Although several reports describe N-glycosylation profiles of recombinant FcgammaRIII glycoproteins, much remains unknown regarding their native glycoforms.	Nitrogen	34-35	Fc gamma receptor IIIa	Homo sapiens	74-85
29426894-5	2018	Our data indicate a distinct and common tendency of the glycoforms exhibited at each N-glycosylation site between the native and the previously reported recombinant FcgammaRIII glycoproteins.	Nitrogen	85-86	Fc gamma receptor IIIa	Homo sapiens	165-176
29259722-8	2017	Results: hLYPD8 was a highly N-glycosylated GPI-anchored protein, like mLypd8.	Nitrogen	29-30	LY6/PLAUR domain containing 8	Homo sapiens	9-15
28497290-7	2017	The results show that the relA/spoT mutant of P. putida KT2440 is able to accumulate mcl-PHAs in both optimal and nitrogen limiting conditions.	Nitrogen	114-122	GTP diphosphokinase	Pseudomonas putida KT2440	26-30
29018032-9	2017	Our results clearly document NAT2 genotype-dependent N-acetylation of hydralazine in human hepatocytes, suggesting that hydralazine efficacy and safety could be improved by NAT2 genotype-dependent dosing strategies.	Nitrogen	29-30	N-acetyltransferase 2	Homo sapiens	173-177
27541867-1	2016	A novel class of dibenzo-fused 1,9-diaza-9a-boraphenalenes featuring zigzag edges with a nitrogen-boron-nitrogen bonding pattern named NBN-dibenzophenalenes (NBN-DBPs) has been synthesized.	Nitrogen	104-112	nibrin	Homo sapiens	135-138
27541867-1	2016	A novel class of dibenzo-fused 1,9-diaza-9a-boraphenalenes featuring zigzag edges with a nitrogen-boron-nitrogen bonding pattern named NBN-dibenzophenalenes (NBN-DBPs) has been synthesized.	Nitrogen	104-112	nibrin	Homo sapiens	158-161
28145580-8	2017	Orai1 and Stim1, two N-glycosylated proteins, are involved in Store-Operated Calcium Entry (SOCE), and are essential for breast tumor cell migration.	Nitrogen	21-22	ORAI calcium release-activated calcium modulator 1	Homo sapiens	0-5
29531809-10	2018	The selective inhibition of nuNCX1 by XIP-NLS increased the percentage of beta III tubulin-positive immature neurons in mature cultures of MAP-2-positive cortical neurons, thus unraveling a new function for nuNCX1 in regulating neuronal differentiation through [Ca2+]n-dependent PTEN/PI3K/Akt pathway.	Nitrogen	15-16	microtubule associated protein 2	Homo sapiens	139-144
29732863-6	2016	The post-anthesis dry matter and N accumulation accounted for 63.0%, 20.1% and 73.3%, 20.5% for the BSX and BMX treatments, respectively, while these proportions for the WDX were 59.3% and 11.6%, respectively.	Nitrogen	33-34	BMX non-receptor tyrosine kinase	Homo sapiens	108-111
31938168-7	2018	Decreased expression of CCDC19 protein was significantly associated with N stage (P = 0.024) and gender (P = 0.022).	Nitrogen	73-74	cilia and flagella associated protein 45	Homo sapiens	24-30
28610393-2	2017	The as-prepared S,N-GQD/P25 composites exhibited excellent photocatalytic hydrogen generation activities, with a significantly extended light absorption range and superior durability without loading any noble metal cocatalyst.	Nitrogen	18-19	tubulin polymerization promoting protein	Homo sapiens	24-27
27829897-1	2016	Rh(II)-satalyzed reactions of aroyldiazomethanes, diazoketoesters and diazodiketones with alpha,beta-unsaturated delta-aminoesters, in contrast to reactions of diazomalonates and other diazoesters, give rise to the Wolff rearrangement and/or oxidative cleavage of the initially formed N-H-insertion products.	Nitrogen	285-286	Rh blood group D antigen	Homo sapiens	0-6
28610393-4	2017	This remarkable improvement in photocatalytic activity of the S,N-GQD/P25 composites can be attributed to that S,N-GQDs play a key role to enhance visible light absorption and facilitate the separation and transfer of photogenerated electrons and holes.	Nitrogen	64-65	tubulin polymerization promoting protein	Homo sapiens	70-73
28610393-4	2017	This remarkable improvement in photocatalytic activity of the S,N-GQD/P25 composites can be attributed to that S,N-GQDs play a key role to enhance visible light absorption and facilitate the separation and transfer of photogenerated electrons and holes.	Nitrogen	113-114	tubulin polymerization promoting protein	Homo sapiens	70-73
28976047-6	2017	In cells grown in poor nitrogen medium, the nitrogen permease reactivator kinase (Npr1) inhibits TORC1 activity and alters its association with Tap42, rendering Tap42-associated phosphatases unresponsive to nitrogen limitation.	Nitrogen	23-31	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	82-86
28976047-6	2017	In cells grown in poor nitrogen medium, the nitrogen permease reactivator kinase (Npr1) inhibits TORC1 activity and alters its association with Tap42, rendering Tap42-associated phosphatases unresponsive to nitrogen limitation.	Nitrogen	44-52	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	82-86
28976047-7	2017	These findings demonstrate a direct role for TORC1 and Tap42-associated phosphatases in sensing nitrogen conditions and unveil an Npr1-dependent mechanism that controls TORC1 and the phosphatases in response to changes in nitrogen quality.	Nitrogen	96-104	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	130-134
28976047-7	2017	These findings demonstrate a direct role for TORC1 and Tap42-associated phosphatases in sensing nitrogen conditions and unveil an Npr1-dependent mechanism that controls TORC1 and the phosphatases in response to changes in nitrogen quality.	Nitrogen	222-230	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	130-134
29180287-2	2018	Single nucleotide polymorphisms in the NAT2 coding exon present in NAT2 haplotypes encode allozymes with reduced N-acetyltransferase activity towards the N-acetylation of arylamine carcinogens and the O-acetylation of their N-hydroxylated metabolites.	Nitrogen	39-40	N-acetyltransferase 2	Homo sapiens	67-71
27265247-3	2016	The systematic change of electron density of the pyridine nitrogens upon alteration of the para-substituent (NO2, CF3, H, F, Me, OMe, NMe2) was confirmed by (15)N NMR and by computation of the natural atomic population and the pi electron population of the nitrogen atoms.	Nitrogen	58-67	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	134-138
29114020-10	2017	Surprisingly, the second causative gene was a mutant allele of TOR1, a gene involved in nitrogen regulation.	Nitrogen	88-96	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	63-67
29114020-16	2017	The second mutant allele contained a nonsense mutation in TOR1, a gene involved in nitrogen regulation of growth.	Nitrogen	83-91	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	58-62
27265247-3	2016	The systematic change of electron density of the pyridine nitrogens upon alteration of the para-substituent (NO2, CF3, H, F, Me, OMe, NMe2) was confirmed by (15)N NMR and by computation of the natural atomic population and the pi electron population of the nitrogen atoms.	Nitrogen	58-66	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	134-138
28972750-0	2017	Low-Valent, High-Spin Chromium-Catalyzed Cleavage of Aromatic Carbon-Nitrogen Bonds at Room Temperature: A Combined Experimental and Theoretical Study.	Nitrogen	69-77	spindlin 1	Homo sapiens	17-21
27877888-10	2016	We conclude that the N-Trt group acts as a cleavable component to induce the lysosomal dissociation of HEE-PRXs, and acid-labile HEE-PRXs with an optimal number of HEE groups (4.1 to 5.4 HEE groups per single beta-CD threaded onto the PRX) have great therapeutic potential for treating NPC disease.	Nitrogen	21-22	periaxin	Homo sapiens	107-110
29062024-1	2017	Antibody-dependent cellular cytotoxicity (ADCC) is promoted through interaction between the Fc region of immunoglobulin G1 (IgG1) and Fcgamma receptor IIIa (FcgammaRIIIa), depending on N-glycosylation of these glycoproteins.	Nitrogen	185-186	Fc gamma receptor IIIa	Homo sapiens	134-155
29062024-1	2017	Antibody-dependent cellular cytotoxicity (ADCC) is promoted through interaction between the Fc region of immunoglobulin G1 (IgG1) and Fcgamma receptor IIIa (FcgammaRIIIa), depending on N-glycosylation of these glycoproteins.	Nitrogen	185-186	Fc gamma receptor IIIa	Homo sapiens	157-169
28550773-3	2017	The nitrogen removal capacity of anammox reactor was nearly deprived within 30days under the stress of 5.0mgL-1 CuNPs and the relative abundance of anammox bacteria (Ca.	Nitrogen	4-12	LLGL scribble cell polarity complex component 1	Homo sapiens	106-111
28315854-5	2017	N-glycosylation mutation of EpCAM was correlated with lower levels of integrin beta1 and fibronectin.	Nitrogen	0-1	integrin subunit beta 1	Homo sapiens	70-84
27411448-1	2016	Because it plays an essential role in nitrogen (N) assimilation and photorespiration, the glutamine synthetase (GS)/glutamate synthase (GOGAT) system is widely accepted as occupying a central position in leaf N metabolism.	Nitrogen	38-46	hypothetical protein	Arabidopsis thaliana	90-110
28979288-8	2017	In contrast, nitrogen (N) deprivation induced TaAMT1;1a, TaAMT1;1b, and TaAMT1;3a gene expressions in the roots and leaves.	Nitrogen	13-21	ammonium transporter 1 member 1	Triticum aestivum	46-52
28979288-8	2017	In contrast, nitrogen (N) deprivation induced TaAMT1;1a, TaAMT1;1b, and TaAMT1;3a gene expressions in the roots and leaves.	Nitrogen	13-21	ammonium transporter 1 member 1	Triticum aestivum	57-63
28979288-8	2017	In contrast, nitrogen (N) deprivation induced TaAMT1;1a, TaAMT1;1b, and TaAMT1;3a gene expressions in the roots and leaves.	Nitrogen	13-21	ammonium transporter 1 member 1	Triticum aestivum	57-63
26931382-2	2016	ALG1 encodes a beta1,4 mannosyltransferase that catalyzes the addition of the first of nine mannose moieties to form a dolichol-lipid linked oligosaccharide intermediate required for proper N-linked glycosylation.	Nitrogen	190-191	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	0-4
31457757-1	2017	The active site of the purple acid phosphatase enzyme has been successfully modeled by a series of hetero-dinuclear M(II)-Fe(III) [M = Zn, Ni, Co, and Cu] type complexes of an unsymmetrical [N6O] ligand that contained a bridging phenoxide moiety and one imidazoyl and three pyridyl moieties as the terminal N-binding sites.	Nitrogen	139-140	acid phosphatase 5, tartrate resistant	Homo sapiens	23-46
28552913-10	2017	Hematocrit and blood urea nitrogen were identified as two covariates that significantly influenced the CL/F.	Nitrogen	26-34	crooked neck pre-mRNA splicing factor 1	Homo sapiens	103-107
27446149-7	2016	Furthermore, enzymes involved in nitrogen metabolism, e.g., nitrate reductase and glutamine synthetase were improved.	Nitrogen	33-41	nitrate reductase [NADH] 1	Zea mays	60-77
28515179-6	2017	Arg2-/- mice had significantly attenuated kidney injury and lower plasma creatinine and blood urea nitrogen levels after renal IRI.	Nitrogen	99-107	arginase type II	Mus musculus	0-4
27271094-10	2017	There was a statistically significant interaction between APOA2 polymorphism and n-6 PUFA intake on 8-isoprostane F2alpha concentration as well as n-3 PUFA intake on serum SOD activity (p-interaction = 0.04 and 0.02, respectively).	Nitrogen	29-30	pumilio RNA binding family member 3	Homo sapiens	85-89
27271589-4	2016	We performed the N-formylation of two chemotactic hexapetides, Met1-Leu2-Lys3-Leu4-Ile5-Val6 and Met1-Met2-Tyr3-Ala4-Leu5-Phe6, carrying out the reaction directly on peptidyl-resin following pre-activation of formic acid with N,N-dicyclohexylcarbodiimmide (DCC) in liquid phase.	Nitrogen	17-18	granzyme M	Homo sapiens	63-67
27693244-3	2017	NOC are agents that induce various N-methylated DNA adducts and O6-methylguanine (O6-MeG), which are removed by base excision repair (BER) and O6-methylguanine-DNA methyltransferase (MGMT), respectively.	Nitrogen	0-1	O-6-methylguanine-DNA methyltransferase	Homo sapiens	143-181
27271589-4	2016	We performed the N-formylation of two chemotactic hexapetides, Met1-Leu2-Lys3-Leu4-Ile5-Val6 and Met1-Met2-Tyr3-Ala4-Leu5-Phe6, carrying out the reaction directly on peptidyl-resin following pre-activation of formic acid with N,N-dicyclohexylcarbodiimmide (DCC) in liquid phase.	Nitrogen	17-18	deleted in lymphocytic leukemia 1	Homo sapiens	68-72
27693244-3	2017	NOC are agents that induce various N-methylated DNA adducts and O6-methylguanine (O6-MeG), which are removed by base excision repair (BER) and O6-methylguanine-DNA methyltransferase (MGMT), respectively.	Nitrogen	0-1	O-6-methylguanine-DNA methyltransferase	Homo sapiens	183-187
27271589-4	2016	We performed the N-formylation of two chemotactic hexapetides, Met1-Leu2-Lys3-Leu4-Ile5-Val6 and Met1-Met2-Tyr3-Ala4-Leu5-Phe6, carrying out the reaction directly on peptidyl-resin following pre-activation of formic acid with N,N-dicyclohexylcarbodiimmide (DCC) in liquid phase.	Nitrogen	17-18	granzyme M	Homo sapiens	97-101
27271589-4	2016	We performed the N-formylation of two chemotactic hexapetides, Met1-Leu2-Lys3-Leu4-Ile5-Val6 and Met1-Met2-Tyr3-Ala4-Leu5-Phe6, carrying out the reaction directly on peptidyl-resin following pre-activation of formic acid with N,N-dicyclohexylcarbodiimmide (DCC) in liquid phase.	Nitrogen	17-18	tripartite motif containing 13	Homo sapiens	117-121
27037794-4	2016	These include the recruitment of annexin A2 to the plasma membrane near soluble N-ethylmaleimide-sensitive factor attachment protein receptor complexes, the role of annexin A2 in the formation of lipid domains at exocytotic sites, and finally the annexin A2 bundling of actin microfilaments associated with chromaffin granules.	Nitrogen	80-81	annexin A2	Homo sapiens	33-43
28596490-6	2017	We discovered that interfering with N-linked glycosylation of GPER, either by mutation of the predicted glycosylation sites or pharmacologically with tunicamycin, drives GPER into the nucleus.	Nitrogen	36-37	G protein-coupled estrogen receptor 1	Homo sapiens	62-66
28516247-5	2017	NAT2 gene dose response (NAT2*5B/*5B &gt; NAT2*5B/*6A &gt; NAT2*6A/*6A) was observed towards the N-acetylation of the NAT2-specific drug sulfamethazine by human hepatocytes both in vitro and in situ.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	25-29
28516247-5	2017	NAT2 gene dose response (NAT2*5B/*5B &gt; NAT2*5B/*6A &gt; NAT2*6A/*6A) was observed towards the N-acetylation of the NAT2-specific drug sulfamethazine by human hepatocytes both in vitro and in situ.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	25-29
28516247-5	2017	NAT2 gene dose response (NAT2*5B/*5B &gt; NAT2*5B/*6A &gt; NAT2*6A/*6A) was observed towards the N-acetylation of the NAT2-specific drug sulfamethazine by human hepatocytes both in vitro and in situ.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	25-29
27249416-11	2016	In our study, serum levels of beta-2 microglobulin and blood urea nitrogen (BUN) were positively associated with A-SAG.	Nitrogen	66-74	S-antigen visual arrestin	Homo sapiens	115-118
28516247-5	2017	NAT2 gene dose response (NAT2*5B/*5B &gt; NAT2*5B/*6A &gt; NAT2*6A/*6A) was observed towards the N-acetylation of the NAT2-specific drug sulfamethazine by human hepatocytes both in vitro and in situ.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	25-29
27252617-3	2016	MTDL-2 showed more high affinity toward the four enzymes than MTDL-1.MTDL-3 and MTDL-4, were designed containing the N-benzylpiperidinium moiety from Donepezil, a metal- chelating 8-hydroxyquinoline group and linked to a N-propargyl core and they were pharmacologically evaluated.The presence of the cyano group in MTDL-3, enhanced binding to AChE, BuChE and MAO A.	Nitrogen	117-118	monoamine oxidase A	Homo sapiens	359-364
28488139-2	2017	The aim of this work was to maximize the production of Aspergillus ibericus lipase under SSF of olive pomace (OP) and wheat bran (WB), evaluating the effect on lipase production of C/N ratio, lipids, phenols, content of sugars of substrates and nitrogen source addition.	Nitrogen	183-184	probable feruloyl esterase A	Triticum aestivum	160-166
28488139-2	2017	The aim of this work was to maximize the production of Aspergillus ibericus lipase under SSF of olive pomace (OP) and wheat bran (WB), evaluating the effect on lipase production of C/N ratio, lipids, phenols, content of sugars of substrates and nitrogen source addition.	Nitrogen	245-253	probable feruloyl esterase A	Triticum aestivum	76-82
28467637-0	2017	N-glycosylation of the beta2 adrenergic receptor regulates receptor function by modulating dimerization.	Nitrogen	0-1	adrenoceptor beta 2	Homo sapiens	23-48
28467637-3	2017	beta2 adrenergic receptor (beta2 AR) has three N-glycosylation sites: Asn6, Asn15 at the N-terminus, and Asn187 at the second extracellular loop (ECL2).	Nitrogen	47-48	adrenoceptor beta 2	Homo sapiens	0-25
28467637-3	2017	beta2 adrenergic receptor (beta2 AR) has three N-glycosylation sites: Asn6, Asn15 at the N-terminus, and Asn187 at the second extracellular loop (ECL2).	Nitrogen	47-48	adrenoceptor beta 2	Homo sapiens	27-35
28467637-7	2017	As decreased beta2 AR homodimer accompanied with reduced efficiency for receptor function, we proposed that the N-glycosylation of beta2 AR regulated receptor function by influencing receptor dimerization.	Nitrogen	112-113	adrenoceptor beta 2	Homo sapiens	13-21
28467637-7	2017	As decreased beta2 AR homodimer accompanied with reduced efficiency for receptor function, we proposed that the N-glycosylation of beta2 AR regulated receptor function by influencing receptor dimerization.	Nitrogen	112-113	adrenoceptor beta 2	Homo sapiens	131-139
27146078-5	2016	The hydracyanation of the acetylene molecule is found to occur via the cleavage of one of acetylene triple bonds at the cost of formation of two Au-C bonds followed by the binding of HCN to the activated C[double bond, length as m-dash]C bond via nitrogen"s lone pair.	Nitrogen	247-255	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	183-186
31966633-10	2017	There was a significant positive correlation of total score of KIM-1 expression and the parameters of kidney function for AKI, including serum creatinine (Cr) and blood urea nitrogen (BUN).	Nitrogen	174-182	hepatitis A virus cellular receptor 1	Homo sapiens	63-68
27009754-3	2016	OBJECTIVES: We investigated the associations of serum n-6 PUFAs and activities of enzymes involved in PUFA metabolism, Delta5 desaturase (D5D) and Delta6 desaturase (D6D), with T2D risk to determine whether serum zinc concentrations could modify these associations.	Nitrogen	16-17	fatty acid desaturase 1	Homo sapiens	125-136
28442602-9	2017	Structure-activity analysis revealed that N-demethylation alters the interaction of PK11195 with the binding pocket of hCAR to favor activation.	Nitrogen	42-43	CXADR Ig-like cell adhesion molecule	Homo sapiens	119-123
27009754-3	2016	OBJECTIVES: We investigated the associations of serum n-6 PUFAs and activities of enzymes involved in PUFA metabolism, Delta5 desaturase (D5D) and Delta6 desaturase (D6D), with T2D risk to determine whether serum zinc concentrations could modify these associations.	Nitrogen	16-17	fatty acid desaturase 1	Homo sapiens	138-141
27285702-15	2016	3, ADG linearly increased with increasing supplementary N intake from both and NPN, with no difference between the 2 supplements.	Nitrogen	56-57	ADG	Bos taurus	3-6
28532839-2	2017	Embryo freezing in liquid nitrogen (LN2) at -196  C has traditionally been the method of choice for archiving mouse lines.	Nitrogen	26-34	NZ lupus nephritis 2	Mus musculus	36-39
27285702-16	2016	In contrast, ADG quadratically increased with increasing supplementary N intake from CSM.	Nitrogen	71-72	ADG	Bos taurus	13-16
28592651-8	2017	Based on these approaches, we were able to validate ARO1, PDC1, CPS1, ASI2, LYP1, and ALP1 allelic variants underlying nitrogen consumption differences between strains, providing evidence of many genes with small phenotypic effects.	Nitrogen	119-127	arginine permease ALP1	Saccharomyces cerevisiae S288C	86-90
26992746-2	2016	The theoretical scenario calculated in this study shows that the annually generated food waste onboard ships in traffic in the Baltic Sea contains about 182tonnes of nitrogen and 34tonnes of phosphorus.	Nitrogen	166-174	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	134-137
28426086-1	2017	Multiple pyrenes as pendants of enantioimpure di-/tripeptides (abbreviated as N-LD-C, N-DL-C, N-LLD-C and N-DDL-C) showed pyrene-origin CPL and CD signals, which were associated with conflicting CPL-/CD-signs, compared to the corresponding enantiopure di-/tri-peptides.	Nitrogen	78-79	hephaestin	Homo sapiens	136-139
28426086-1	2017	Multiple pyrenes as pendants of enantioimpure di-/tripeptides (abbreviated as N-LD-C, N-DL-C, N-LLD-C and N-DDL-C) showed pyrene-origin CPL and CD signals, which were associated with conflicting CPL-/CD-signs, compared to the corresponding enantiopure di-/tri-peptides.	Nitrogen	78-79	hephaestin	Homo sapiens	195-198
26992746-5	2016	Future regulations for sewage discharge in the Baltic Sea will require significant reduction of total nitrogen and phosphorus released.	Nitrogen	102-110	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	54-57
26634234-5	2016	The X-ray structures of E-1a, E-1b and E-1c show a slightly shortened N-C bond to the alkene moieties.	Nitrogen	70-71	small nucleolar RNA, H/ACA box 73B	Homo sapiens	39-43
28611678-11	2017	EDX showed that KLK4 inner enamel contained less calcium and phosphorus and more nitrogen than control inner enamel and KLK4 outer enamel.	Nitrogen	81-89	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	Mus musculus	16-20
26880784-2	2016	We report on common and strain-specific responses to nitrogen (N) starvation recorded in four closely related symbiotic Desmodesmus strains from taxonomically very distant animals (hydroids, a sponge and a polychaete) dwelling in the White Sea.	Nitrogen	53-61	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	240-243
28425714-3	2017	Prehydrated electron attachment to 1a and 2 at 77 K produced transient azide anion radical (RN3 -) which reacts via rapid N2 loss at 77 K, forming nitrene anion radical (RN -).	Nitrogen	122-124	drosha ribonuclease III	Homo sapiens	92-95
28548521-0	2017	Double-Quantum Spin-Relaxation Limits to Coherence of Near-Surface Nitrogen-Vacancy Centers.	Nitrogen	67-75	spindlin 1	Homo sapiens	15-19
26654979-10	2016	Among the peptides/proteins identified, ACSL, ACOX2, MTP, and THIKB contribute to regulation of fatty acid metabolism and ARG1, ARLY, and OAT, which regulate nitrogen and ammonia metabolism having direct relevance to ethanol-induced liver injury.	Nitrogen	158-166	acyl-Coenzyme A oxidase 2, branched chain	Mus musculus	46-51
28548521-1	2017	We probe the relaxation dynamics of the full three-level spin system of near-surface nitrogen-vacancy (NV) centers in diamond to define a T_{1} relaxation time that sets the T_{2}&lt;=2T_{1} coherence limit of the NV"s subset qubit superpositions.	Nitrogen	85-93	spindlin 1	Homo sapiens	57-61
28289995-5	2017	In addition, from the UV-vis titration, fluorescence titration,Job"s plot and 1H NMR spectra analysis, we could primarily confirm that three important coordinative sites of P-1 for Al3+ were from imine nitrogen and tertiary amine nitrogen and formed a 1:1 complex.	Nitrogen	202-210	crystallin gamma F, pseudogene	Homo sapiens	173-176
28289995-5	2017	In addition, from the UV-vis titration, fluorescence titration,Job"s plot and 1H NMR spectra analysis, we could primarily confirm that three important coordinative sites of P-1 for Al3+ were from imine nitrogen and tertiary amine nitrogen and formed a 1:1 complex.	Nitrogen	230-238	crystallin gamma F, pseudogene	Homo sapiens	173-176
27979268-1	2017	An amperometric non-enzymatic glucose sensor was developed based on nitrogen-doped graphene with dispersed copper nanoparticles (Cu-NGr).	Nitrogen	68-76	reticulon 4 receptor	Homo sapiens	132-135
26859071-0	2016	Synthesis and in vitro antitumour activity of tiazofurin analogues with nitrogen functionalities at the C-2" position.	Nitrogen	72-80	complement C2	Homo sapiens	104-107
28446919-3	2017	Under long photoperiod, high N supply decreased net photosynthesis; decreased chlorophyll a and chlorophyll a/b; decreased ascorbate peroxidase (APX), catalase (CAT), and superoxide dismutase (SOD) activities; decreased ascorbate, glutathione, soluble protein, and soluble sugar; destroyed mesophyll cell integrity; and increased [Formula: see text], malondialdehyde, and proline in both NA5 and NA9.	Nitrogen	29-30	prx7	Hordeum vulgare	133-143
28339983-6	2017	These data demonstrate that ACR11 is an activator of GS2, giving it a mechanistic role in the nitrogen assimilation of A. thaliana.	Nitrogen	94-102	glutamine synthetase 2	Arabidopsis thaliana	53-56
26859071-1	2016	Synthesis of three tiazofurin (1) isosteres with nitrogen functionalities at the C-2" position (N3, NH2 and NH3(+)Cl(-)) has been achieved, in multistep sequences, starting from monoacetone d-glucose.	Nitrogen	49-57	complement C2	Homo sapiens	81-84
27220433-8	2016	Compared with NS group, the cerebral NSE mRNA and protein expression at each time point in H2S group after exposure were significantly increased (P&lt;0.01).	Nitrogen	14-16	enolase 2	Rattus norvegicus	37-40
28456217-5	2017	The hygrometer HMT 333 was chosen to measure the relative humidity of the outgoing nitrogen stream at five levels.	Nitrogen	83-91	histamine N-methyltransferase	Homo sapiens	15-18
28272356-8	2017	The results revealed that Se/N codoping of TiO2 reduces the band gap due to mixing of N2p with O2p orbitals in the valence band and also introduces additional electronic states originating from Se3p orbitals in the band gap.	Nitrogen	29-30	immunoglobulin kappa variable 1D-39	Homo sapiens	95-98
27220433-9	2016	2 Compared with NS group, the cerebral AQP4 and COX-2 mRNA and protein expression at each time point in H2S group after exposure were significantly increased (P&lt;0.01).	Nitrogen	16-18	aquaporin 4	Rattus norvegicus	39-43
27673439-0	2017	N2 non-thermal atmospheric pressure plasma promotes wound healing in vitro and in vivo: Potential modulation of adhesion molecules and matrix metalloproteinase-9.	Nitrogen	0-2	matrix metallopeptidase 9	Rattus norvegicus	135-161
26791391-10	2016	Moreover, distinct alterations in the N-glycome were identified, suggesting cross-links between DIAPH3 and glycosyltransferase networks.	Nitrogen	38-39	diaphanous related formin 3	Homo sapiens	96-102
27927990-1	2017	The membrane protein RFT1 is essential for normal protein N-glycosylation, but its precise function is not known.	Nitrogen	58-59	glycolipid translocation protein	Saccharomyces cerevisiae S288C	21-25
27927990-4	2017	We now report that lack of T. brucei RFT1 (TbRFT1) not only affects protein N-glycosylation but also glycosylphosphatidylinositol (GPI) anchor side-chain modification.	Nitrogen	76-77	glycolipid translocation protein	Saccharomyces cerevisiae S288C	37-41
29367694-6	2018	Transcriptome analysis revealed that four nitrogen-related clusters including amino acid synthesis-related genes and members of NRT1/PTR family were modulated by both NLP7 and NRT1.1.	Nitrogen	42-50	nitrate transporter 1.1	Arabidopsis thaliana	128-132
29367694-6	2018	Transcriptome analysis revealed that four nitrogen-related clusters including amino acid synthesis-related genes and members of NRT1/PTR family were modulated by both NLP7 and NRT1.1.	Nitrogen	42-50	NIN like protein 7	Arabidopsis thaliana	167-171
29367694-6	2018	Transcriptome analysis revealed that four nitrogen-related clusters including amino acid synthesis-related genes and members of NRT1/PTR family were modulated by both NLP7 and NRT1.1.	Nitrogen	42-50	nitrate transporter 1.1	Arabidopsis thaliana	176-180
26827137-5	2016	The piperidine nitrogen was functionalized with carbamates, amides, and sulfonamides, providing compounds that are potent inverse agonists of hCB1 with good selectivity for hCB1 over hCB2.	Nitrogen	15-23	cannabinoid receptor 2	Homo sapiens	183-187
29227091-2	2018	In this study, we surprisingly found that, under vacuum-UV (VUV) excitation, a gaseous mixture of CH2Cl2/H2O/analyte (OVOCs) in N2 buffer generated large amounts of H3O+ and protonated analyte even when the photon energy was lower than the ionization energy of the neutral species involved.	Nitrogen	128-130	H3 clustered histone 15	Homo sapiens	165-168
28098177-2	2017	X-ray diffraction structures of oxidoreductase flavoenzymes have revealed recurrent features which facilitate catalysis, such as a hydrogen bond between a main chain nitrogen atom and the flavin redox center (N5).	Nitrogen	166-174	thioredoxin reductase 1	Homo sapiens	32-46
26899143-3	2016	Among these regulators, two positive regulators (Gln3p and Gat1p) could be phosphorylated and sequestered in the cytoplasm leading to the transcription of non-preferred nitrogen metabolic genes being repressed.	Nitrogen	169-177	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	49-54
26660433-3	2016	Enzyme binding and kinetic analyses on substrate analogues with P and As substituting for N in the trimethylammonium group show that the analogues are good BBOX substrates, which follow the efficiency trend N(+) &gt;P(+) &gt;As(+).	Nitrogen	90-91	gamma-butyrobetaine hydroxylase 1	Homo sapiens	156-160
27845046-2	2017	Here we report a T-DNA insertion mutant (atdfb-3) of the plastidial folylpolyglutamate synthetase gene (AtDFB) was defective in folate metabolism and nitrogen metabolism under nitrate-limited conditions in darkness.	Nitrogen	150-158	DHFS-FPGS homolog B	Arabidopsis thaliana	41-46
27845046-2	2017	Here we report a T-DNA insertion mutant (atdfb-3) of the plastidial folylpolyglutamate synthetase gene (AtDFB) was defective in folate metabolism and nitrogen metabolism under nitrate-limited conditions in darkness.	Nitrogen	150-158	DHFS-FPGS homolog B	Arabidopsis thaliana	104-109
29329315-14	2018	The aim of this report is to provide an inspiration for future detailed experiments aimed at explaining the role of N-glycosylation in the activation process of prodomain of MMP-9.	Nitrogen	116-117	matrix metallopeptidase 9	Homo sapiens	174-179
26651534-0	2016	On an Easy Way To Prepare Metal-Nitrogen Doped Carbon with Exclusive Presence of MeN4-type Sites Active for the ORR.	Nitrogen	32-40	cyclin dependent kinase inhibitor 1B	Homo sapiens	81-85
29375510-6	2017	This suggests a trend to streamline the regulation of C/N metabolism in late-branching Prochlorococcus strains (MED4 and SS120), in adaptation to the rather stable conditions found in the oligotrophic ocean gyres where this microorganism is most abundant.	Nitrogen	56-57	mediator complex subunit 4	Homo sapiens	112-116
27852617-11	2017	CONCLUSION: Long-chain n-3 PUFA supplementation augments increases in muscle function and quality in older women but not in older men after resistance exercise training.	Nitrogen	14-15	pumilio RNA binding family member 3	Homo sapiens	27-31
27770224-2	2017	In this study, crucial genes like ARO8 and ARO10 of Ehrlich pathway for 2-PE synthesis and key transcription factor ARO80 in Saccharomyces cerevisiae were re-regulated using constitutive promoter; in the meantime, the effect of nitrogen source in synthetic complete (SC) medium with L-phenylalanine (L-Phe) on Aro8/Aro9 and Aro10 was investigated.	Nitrogen	228-236	bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	34-38
27770224-2	2017	In this study, crucial genes like ARO8 and ARO10 of Ehrlich pathway for 2-PE synthesis and key transcription factor ARO80 in Saccharomyces cerevisiae were re-regulated using constitutive promoter; in the meantime, the effect of nitrogen source in synthetic complete (SC) medium with L-phenylalanine (L-Phe) on Aro8/Aro9 and Aro10 was investigated.	Nitrogen	228-236	bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	310-314
31275021-0	2017	The chimeric repressor for the GATA4 transcription factor improves tolerance to nitrogen deficiency in Arabidopsis.	Nitrogen	80-88	GATA transcription factor 4	Arabidopsis thaliana	31-36
31275021-3	2017	Here, we report that the expression of the chimeric repressor for the GATA4 transcription factor (35S:GATA4-SRDX) improved tolerance to nitrogen deficiency in Arabidopsis thaliana.	Nitrogen	136-144	GATA transcription factor 4	Arabidopsis thaliana	70-75
31275021-3	2017	Here, we report that the expression of the chimeric repressor for the GATA4 transcription factor (35S:GATA4-SRDX) improved tolerance to nitrogen deficiency in Arabidopsis thaliana.	Nitrogen	136-144	GATA transcription factor 4	Arabidopsis thaliana	102-107
31275021-4	2017	35S:GATA4-SRDX seedlings were significantly larger than wild type under nitrogen-sufficient and -deficient conditions (10 and 0.5 mM NH4NO3, respectively).	Nitrogen	72-80	GATA transcription factor 4	Arabidopsis thaliana	4-9
31275021-6	2017	The expression levels of NITRATE TRANSPORTER 2.1, ASPARAGINE SYNTHETASE and NITRATE REDUCTASE 1 were significantly higher in roots of 35S:GATA4-SRDX plants than in wild type under nitrogen-sufficient conditions.	Nitrogen	180-188	GATA transcription factor 4	Arabidopsis thaliana	138-143
31275021-7	2017	Under nitrogen-deficient conditions, the expression of genes for cytosolic glutamine synthetases was upregulated in shoots of 35S:GATA4-SRDX plants compared with wild type.	Nitrogen	6-14	GATA transcription factor 4	Arabidopsis thaliana	130-135
31275021-8	2017	This upregulation of nitrogen transporter and nitrogen assimilation-related genes might confer tolerance to nitrogen deficiency in 35S:GATA4-SRDX plants.	Nitrogen	21-29	GATA transcription factor 4	Arabidopsis thaliana	135-140
29303997-3	2018	In this study, we carried out a detailed investigation of this question by using tetherin variants in which one or both sites of N-linked glycosylation were mutated (N65A, N92A, and N65,92A), and chemical inhibitors that prevent glycosylation at specific stages of oligosaccharide were added or modified.	Nitrogen	129-130	bone marrow stromal cell antigen 2	Homo sapiens	81-89
29303997-7	2018	A role for glycosylation in cell-surface tetherin expression is supported by tunicamycin treatment, which inhibits the first step of N-linked glycosylation and impairs both cell-surface expression and antiviral activity.	Nitrogen	133-134	bone marrow stromal cell antigen 2	Homo sapiens	41-49
29607936-9	2018	Moreover, we found that STT3B-dependent posttranslational N-glycosylation at N98 residue occurred in G101S TTR but not in other TTR variants, possibly due to amino acid alterations that increase N-glycosylation preference or accelerate rigid structure formation susceptible to N-glycosylation.	Nitrogen	77-78	transthyretin	Homo sapiens	107-110
29607936-9	2018	Moreover, we found that STT3B-dependent posttranslational N-glycosylation at N98 residue occurred in G101S TTR but not in other TTR variants, possibly due to amino acid alterations that increase N-glycosylation preference or accelerate rigid structure formation susceptible to N-glycosylation.	Nitrogen	77-78	transthyretin	Homo sapiens	107-110
29683099-7	2018	Non-nitrogen containing bisphosphonates inhibit farnesyl diphosphate synthase which produces farnesyl pyrophosphate.	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	48-77
31275021-8	2017	This upregulation of nitrogen transporter and nitrogen assimilation-related genes might confer tolerance to nitrogen deficiency in 35S:GATA4-SRDX plants.	Nitrogen	46-54	GATA transcription factor 4	Arabidopsis thaliana	135-140
31275021-8	2017	This upregulation of nitrogen transporter and nitrogen assimilation-related genes might confer tolerance to nitrogen deficiency in 35S:GATA4-SRDX plants.	Nitrogen	46-54	GATA transcription factor 4	Arabidopsis thaliana	135-140
25814621-6	2016	Simple regression analysis showed that the serum irisin concentrations in type 2 diabetes mellitus patients were negatively correlated with age, fasting plasma glucose, homeostasis model assessment of insulin resistance, blood urea nitrogen, creatinine, and positively correlated with creatinine clearance and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers treatment.	Nitrogen	232-240	fibronectin type III domain containing 5	Homo sapiens	49-55
27760464-6	2016	165 site-specific N-glycopeptides representative of all N-glycosylation sites were identified from AGP 1 and AGP 2 isoforms.	Nitrogen	18-19	orosomucoid 2	Homo sapiens	109-114
29115386-11	2018	The concentrations of blood urea nitrogen and serum creatinine in the PYP + cisplatin group were lower than those in the cisplatin group.	Nitrogen	33-41	pyrophosphatase (inorganic) 1	Mus musculus	70-73
29218634-2	2018	N2OR is the terminal reductase in a respiratory chain converting N2O to N2 in denitrifying bacteria; COX is the terminal oxidase of the aerobic respiratory chain of certain bacteria and eukaryotic organisms transforming O2 to H2O accompanied by proton pumping.	Nitrogen	0-2	cytochrome c oxidase subunit 7A1	Bos taurus	101-104
26560048-8	2016	Among the total of 48 analogs screened, only quaternary nitrogen containing analogs 6a-g and 10a, 10h-l displayed promising P-gp induction activity; whereas non-planar non-quaternary analogs 9a-m, 13a-n, 15a-h were devoid of this activity.	Nitrogen	56-64	phosphoglycolate phosphatase	Homo sapiens	124-128
28988820-4	2017	ATF4 upregulation by p62 deficiency in the stroma activates glucose carbon flux through a pyruvate carboxylase-asparagine synthase cascade that results in asparagine generation as a source of nitrogen for stroma and tumor epithelial proliferation.	Nitrogen	192-200	activating transcription factor 4	Homo sapiens	0-4
28988820-4	2017	ATF4 upregulation by p62 deficiency in the stroma activates glucose carbon flux through a pyruvate carboxylase-asparagine synthase cascade that results in asparagine generation as a source of nitrogen for stroma and tumor epithelial proliferation.	Nitrogen	192-200	nucleoporin 62	Homo sapiens	21-24
27933881-3	2016	Structural, spectroscopic, and computational data suggest that the spin density is centered on one of the nitrogen atoms of the former azo group.	Nitrogen	106-114	spindlin 1	Homo sapiens	67-71
27523475-6	2016	Localisation of these mutations on the hFMO3 model provided a structural explanation for their observed biological effects and docked models of hFMO3-drug complexes gave insights into their binding mechanism demonstrating that nitrogen- and sulfur-containing substrates interact with the isoalloxazine ring through Pi-Cation interaction and Pi-Sulfur interactions, respectively.	Nitrogen	227-235	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	144-149
27739682-2	2016	We investigate the possibility of spin-forbidden transitions between the lowest energy electronic states with different spin multiplicities in the rubredoxin active site models [Fe(SCH3)4]n (n = 2-, 1-, 0) using nonadiabatic transition state theory (NA-TST).	Nitrogen	4-5	spindlin 1	Homo sapiens	34-38
26742884-5	2016	Protein spots of interest were subjected to protein identification by mass spectrometry.In total, 670 protein spots were detected by 2DE, 28 of which showed more than 1.5-fold different intensity (P &lt; 0.05) between the AS-C and AS-N samples.	Nitrogen	234-235	steroid sulfatase	Homo sapiens	222-226
27739682-2	2016	We investigate the possibility of spin-forbidden transitions between the lowest energy electronic states with different spin multiplicities in the rubredoxin active site models [Fe(SCH3)4]n (n = 2-, 1-, 0) using nonadiabatic transition state theory (NA-TST).	Nitrogen	4-5	spindlin 1	Homo sapiens	120-124
28850721-6	2017	Transcriptome analysis revealed that four nitrogen-related clusters were enriched in the differentially expressed genes of the cpsf30 mutant.	Nitrogen	42-50	cleavage and polyadenylation specificity factor 30	Arabidopsis thaliana	127-133
29169396-6	2017	For the APOE SNP rs1064725, only TT homozygotes showed a significant reduction in total cholesterol after the MUFA diet (n = 33; -0.71 +- 1.88 mmol/l) compared to the SFA (n = 38; 0.34 +- 0.55 mmol/l) or n-6 PUFA diets (n = 37; -0.08 +- 0.73 mmol/l) (P = 0.004).	Nitrogen	29-30	pumilio RNA binding family member 3	Homo sapiens	208-212
29109265-3	2017	Both Sil1 and Lhs1 are glycoproteins, but how N-glycosylation regulates their function is not known.	Nitrogen	46-47	Hsp70 family chaperone LHS1	Saccharomyces cerevisiae S288C	14-18
29109265-6	2017	N-glycosylation of Lhs1 is largely Ost3-independent and independent of the CxxC motif.	Nitrogen	0-1	Hsp70 family chaperone LHS1	Saccharomyces cerevisiae S288C	19-23
29109265-7	2017	Unglycosylated Sil1 is not only functional but is more effective at rescuing loss of Lhs1 activity than N-glycosylated Sil1.	Nitrogen	104-105	Hsp70 family chaperone LHS1	Saccharomyces cerevisiae S288C	85-89
27119042-1	2016	A ratiometric probe for determining ferric ions (Fe(3+)) was developed based on nitrogen-doped carbon dots (CDs) and rhodamine B isothiocyanate (RhB), which was then applied to selective detection of Fe(3+) in PB buffer solution, lake water, and tap water.	Nitrogen	80-88	filamin B	Homo sapiens	246-249
28750239-2	2017	In this paper, an "off-on" method for highly sensitive and selective detection of Hg2+ and l-cysteine (l-Cys) or Hg2+ and I- using home-made nitrogen-doped carbon quantum dots (N-CQDs) as fluorescent probe was reported.	Nitrogen	141-149	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	82-85
28750239-2	2017	In this paper, an "off-on" method for highly sensitive and selective detection of Hg2+ and l-cysteine (l-Cys) or Hg2+ and I- using home-made nitrogen-doped carbon quantum dots (N-CQDs) as fluorescent probe was reported.	Nitrogen	141-149	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	113-116
26645810-1	2016	The structural features, spectroscopic properties, and interaction energies of the linear proton-bound complexes of OCH(+) and its sulfur analog SCH(+) with N2 were investigated using the high-level ab initio methods MP2 and CCSD(T) as well as density functional theory with the aug-cc-pVXZ (X = D, T) basis sets.	Nitrogen	157-159	tryptase pseudogene 1	Homo sapiens	217-220
30167213-0	2017	Spin-manipulated nanoscopy for single nitrogen-vacancy center localizations in nanodiamonds.	Nitrogen	38-46	spindlin 1	Homo sapiens	0-4
26877051-6	2016	The total inorganic nitrogen removal efficiency by the ANITA Mox reactor was about 70% at SRR of 1.0 g/(m(2) d).	Nitrogen	20-28	monooxygenase DBH like 1	Homo sapiens	61-64
29106622-8	2017	Proteomic analyses of N-glycosylated proteins identified GLU23/PYK10 and PRX34 as N-glycosylation targets of LRG1 activity.	Nitrogen	82-83	peroxidase CB	Arabidopsis thaliana	73-78
26584857-6	2015	This result allows us to determine why the N2 release is easier for the DBH case via a concerted mechanism compared to the stepwise mechanism found in the DBOH system.	Nitrogen	43-45	dopamine beta-hydroxylase	Homo sapiens	72-75
28668561-5	2017	Results showed that the ZnO NPs with low concentration (&lt;=5mgL-1) was profitable for nitrogen removal while the high concentration performed inhibition, and it lowered the abundance of both AOB and NOB while enhanced that of AAOB.	Nitrogen	88-96	LLGL scribble cell polarity complex component 1	Homo sapiens	62-67
28784321-2	2017	In this study, the roles of YHM2, ODC1 and ODC2 in the assimilation of nitrogen and in the biosynthesis of lysine have been investigated.	Nitrogen	71-79	Yhm2p	Saccharomyces cerevisiae S288C	28-32
26551034-3	2015	A stabilizing interaction between a nitrogen atom lone pair and an aromatic sulfur system (nN   sigma*S-X) in 32 was exploited to conformationally constrain a biaryl linkage and allow contact with key residues in GKRP.	Nitrogen	36-44	glucokinase regulator	Homo sapiens	213-217
28410627-3	2017	METHODS: This systematic review and meta-analysis aims to compare the levels of PUFA indices, including eicosapentaenoic acid, docosahexaenoic acid, arachidonic acid, total n-3, total n-6, and the n-6/n-3 ratio between women with PND and healthy control subjects.	Nitrogen	33-34	pumilio RNA binding family member 3	Homo sapiens	80-84
26671672-7	2015	Although other N-glycosylated proteins are critical to early development, overexpression of TRPM7 in Xenopus laevis embryos was sufficient to fully rescue the gastrulation defect caused by loss of hepatocystin.	Nitrogen	15-16	transient receptor potential cation channel subfamily M member 7 L homeolog	Xenopus laevis	92-97
28774774-0	2017	Saccharomyces cerevisiae KTR4, KTR5 and KTR7 encode mannosyltransferases differentially involved in the N- and O-linked glycosylation pathways.	Nitrogen	104-105	putative mannosyltransferase	Saccharomyces cerevisiae S288C	40-44
28817930-4	2017	Protein X-ray crystallography established that 3-unsubstituted 2,4-oxazolidinediones bound to CA II via an interaction of the acidic ring nitrogen with the CA II active site zinc, as well as two hydrogen bonds between the oxazolidinedione ring oxygen and the CA II protein backbone.	Nitrogen	138-146	carbonic anhydrase 2	Homo sapiens	94-99
26768186-1	2015	Phosphoglucomutase 1 (PGM1, EC 5.4.2.2) plays a critical role in glucose homeostasis and is also essential for protein N-glycosylation.	Nitrogen	119-120	phosphoglucomutase 1	Homo sapiens	0-20
26768186-1	2015	Phosphoglucomutase 1 (PGM1, EC 5.4.2.2) plays a critical role in glucose homeostasis and is also essential for protein N-glycosylation.	Nitrogen	119-120	phosphoglucomutase 1	Homo sapiens	22-26
27600106-11	2017	OA offered mixed inhibition of UGT1A3-mediated 4-MU-beta-d-glucuronidation (IC50 0.336 +- 0.013 muM; Ki 0.176 +- 0.007 muM) and competitively inhibited UGT1A4-mediated trifluoperazine-N-glucuronidation (IC50 5.468 +- 0.697 muM; Ki 6.298 +- 0.891 muM).	Nitrogen	184-185	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	31-37
26607208-2	2015	We investigated whether the action of N/OFQ involves the modulation of P2X3 , a pain-transducing ionotropic receptor.	Nitrogen	38-39	purinergic receptor P2X 3	Rattus norvegicus	71-75
26607208-6	2015	Immunocytochemical staining also revealed enhanced P2X3 immunoreactivity beneath the neuronal membrane and an increased percentage of P2X3 -positive neurons after treatment with N/OFQ.	Nitrogen	178-179	purinergic receptor P2X 3	Rattus norvegicus	51-55
26607208-6	2015	Immunocytochemical staining also revealed enhanced P2X3 immunoreactivity beneath the neuronal membrane and an increased percentage of P2X3 -positive neurons after treatment with N/OFQ.	Nitrogen	178-179	purinergic receptor P2X 3	Rattus norvegicus	134-138
28617578-6	2017	Using synthetic MUC16 glycopeptides, we developed novel N-glycosylation site directed monoclonal antibodies that block Galectin-3-mediated MUC16 interactions with cell surface signaling molecules.	Nitrogen	56-57	mucin 16, cell surface associated	Homo sapiens	16-21
28617578-6	2017	Using synthetic MUC16 glycopeptides, we developed novel N-glycosylation site directed monoclonal antibodies that block Galectin-3-mediated MUC16 interactions with cell surface signaling molecules.	Nitrogen	56-57	mucin 16, cell surface associated	Homo sapiens	139-144
26607208-8	2015	Our results suggest that the activation of ORL1 receptors by N/OFQ can potentiate P2X3 receptors in primary cultures of neonatal trigeminal neurons, which may be a mechanism for the nociceptive role of N/OFQ in the modulation of craniofacial pain.	Nitrogen	61-62	purinergic receptor P2X 3	Rattus norvegicus	82-86
28688958-1	2017	A new library of deoxycholic acid derivatives bearing nitrogen-containing moieties at the C-3 position was synthesised from epoxy derivative 1 via an epoxide ring-opening reaction promoted by aliphatic or cyclic diamines and fully characterised by NMR and mass-spectroscopy.	Nitrogen	54-62	complement C3	Homo sapiens	90-93
28743755-3	2017	Unlike F-box proteins in other SCF complexes, FBXO27 is subject to N-myristoylation, which localizes it to membranes, allowing it to accumulate rapidly around damaged lysosomes.	Nitrogen	67-68	F-box protein 27	Homo sapiens	46-52
26607208-8	2015	Our results suggest that the activation of ORL1 receptors by N/OFQ can potentiate P2X3 receptors in primary cultures of neonatal trigeminal neurons, which may be a mechanism for the nociceptive role of N/OFQ in the modulation of craniofacial pain.	Nitrogen	202-203	purinergic receptor P2X 3	Rattus norvegicus	82-86
26452604-5	2015	The N-glycosylation of TNFR1 could facilitate its capability of binding to TNFalpha and further promote the formation of TNFalpha autocrine loop in microglia stimulated by TNFalpha, resulting in excessive microglia activation and CNS inflammation.	Nitrogen	4-5	TNF receptor superfamily member 1A	Homo sapiens	23-28
28601511-3	2017	Molecular modelling using our CYP24A1 homology model showed the inhibitors to fill the hydrophobic binding site, forming key transition metal interaction between the imidazole nitrogen and the haem Fe3+ and multiple interactions with the active site amino acid residues.	Nitrogen	176-184	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	30-37
26452604-8	2015	These findings indicated that the N-glycosylation of TNFR1 played an important role during microglia activation in CNS inflammation.	Nitrogen	34-35	TNF receptor superfamily member 1A	Homo sapiens	53-58
26422404-5	2015	We made use of different bacterial mutants to finely modulate NO levels inside M. truncatula root nodules and to examine the consequence on tyrosine nitration of the plant glutamine synthetase, a protein responsible for assimilation of the ammonia released by nitrogen fixation.	Nitrogen	260-268	LOC11405318	Medicago truncatula	172-192
28067406-8	2017	Fluorescence-activated cell sorting-based Forster resonance energy transfer assays further demonstrated that N-glycosylation is indispensable for the Ninj1 cis-interaction, and a formaldehyde cross-linking assay confirmed that interruption of N-glycosylation by Asn substitution disrupted Ninj1 homomeric complex formation.	Nitrogen	109-110	ninjurin 1	Homo sapiens	150-155
28067406-8	2017	Fluorescence-activated cell sorting-based Forster resonance energy transfer assays further demonstrated that N-glycosylation is indispensable for the Ninj1 cis-interaction, and a formaldehyde cross-linking assay confirmed that interruption of N-glycosylation by Asn substitution disrupted Ninj1 homomeric complex formation.	Nitrogen	109-110	ninjurin 1	Homo sapiens	289-294
28067406-8	2017	Fluorescence-activated cell sorting-based Forster resonance energy transfer assays further demonstrated that N-glycosylation is indispensable for the Ninj1 cis-interaction, and a formaldehyde cross-linking assay confirmed that interruption of N-glycosylation by Asn substitution disrupted Ninj1 homomeric complex formation.	Nitrogen	150-151	ninjurin 1	Homo sapiens	289-294
28067406-9	2017	In silico analysis revealed that Ninj1 is highly conserved in vertebrates and that the conserved sequence contains an N-glycosylation motif and cis-interacting intracellular region, which participate in Ninj1 homomer assembly.	Nitrogen	33-34	ninjurin 1	Homo sapiens	203-208
26560030-2	2015	Argininosuccinate synthase (ASS1) is a urea cycle enzyme that is essential in the conversion of nitrogen from ammonia and aspartate to urea.	Nitrogen	96-104	argininosuccinate synthase 1	Homo sapiens	0-26
28575798-3	2017	Here, we exhaustively assess the atomistic binding interactions of this compound with both CCR5 and CXCR4, and we find that binding is driven by pi-stacking interactions between aromatic rings on the ligand and receptor residues, as well as electrostatic interactions involving the protonated piperidine nitrogen.	Nitrogen	304-312	C-C motif chemokine receptor 5	Homo sapiens	91-95
26560030-2	2015	Argininosuccinate synthase (ASS1) is a urea cycle enzyme that is essential in the conversion of nitrogen from ammonia and aspartate to urea.	Nitrogen	96-104	argininosuccinate synthase 1	Homo sapiens	28-32
28575798-3	2017	Here, we exhaustively assess the atomistic binding interactions of this compound with both CCR5 and CXCR4, and we find that binding is driven by pi-stacking interactions between aromatic rings on the ligand and receptor residues, as well as electrostatic interactions involving the protonated piperidine nitrogen.	Nitrogen	304-312	C-X-C motif chemokine receptor 4	Homo sapiens	100-105
26560030-3	2015	A decrease in nitrogen flux through ASS1 in the liver causes the urea cycle disorder citrullinaemia.	Nitrogen	14-22	argininosuccinate synthase 1	Homo sapiens	36-40
28596490-6	2017	We discovered that interfering with N-linked glycosylation of GPER, either by mutation of the predicted glycosylation sites or pharmacologically with tunicamycin, drives GPER into the nucleus.	Nitrogen	36-37	G protein-coupled estrogen receptor 1	Homo sapiens	170-174
26581175-5	2015	Polymeric chains of nitrogen were found in the high-pressure C2/c phase of CsN2.	Nitrogen	20-28	casein beta	Homo sapiens	75-79
26555173-2	2015	Here, we delineate a pathway in which EGFR signaling, by increasing glucose uptake, promotes N-glycosylation of sterol regulatory element-binding protein (SREBP) cleavage-activating protein (SCAP) and consequent activation of SREBP-1, an ER-bound transcription factor with central roles in lipid metabolism.	Nitrogen	93-94	sterol regulatory element binding transcription factor 1	Homo sapiens	226-233
28752039-3	2017	INH N-acetylation rates in vitro exhibited a robust and highly significant (P&lt;0.005) NAT2 phenotype-dependent metabolism.	Nitrogen	1-2	N-acetyltransferase 2	Homo sapiens	88-92
26424406-2	2015	The characteristic cyclic aminal was constructed by late-stage C-H functionalization at the position adjacent to the lactam nitrogen using a combination of CrO3 and nBu4 NIO4 and subsequent Bi(OTf)3 -mediated cyclization.	Nitrogen	124-132	POU class 5 homeobox 1	Homo sapiens	193-198
29122357-8	2017	Urinary and renal levels of KIM-1 were positively correlated with blood urea nitrogen and proteinuria, while they were negatively correlated with eGFR at both baseline and after two years follow-up.	Nitrogen	77-85	hepatitis A virus cellular receptor 1	Homo sapiens	28-33
29122357-9	2017	Moreover, plasma KIM-1 levels were associated with blood urea nitrogen and proteinuria as well.	Nitrogen	62-70	hepatitis A virus cellular receptor 1	Homo sapiens	17-22
26276083-6	2015	Studies showed the involvement of CYP1A2, CYP2B6, CYP2C19, and CYP3A4 in N-dealkylation of all three compounds and additionally CYP2D6 for lefetamine and NEDPA.	Nitrogen	73-74	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	34-40
28485854-6	2017	Following LPS challenge, podocyte sEH-deficient mice exhibited lower kidney injury, proteinuria, and blood urea nitrogen concentrations than controls suggestive of preserved renal function.	Nitrogen	112-120	epoxide hydrolase 2, cytoplasmic	Mus musculus	34-37
25990584-1	2015	The study showed that the open water of the Bothnian Sea (BS) is likely to have shifted from altering nitrogen and phosphorous limitations of the spring bloom to more nitrogen-limited conditions during the last 20 years.	Nitrogen	102-110	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	53-56
28789064-4	2017	Given the presence of the intrinsic nitrogen hyperfine spin transitions, we experimentally show that when the ratio between the hyperfine linewidth and their separation is   1/4, square-wave based frequency modulation generates the steepest slope at modulation depths exceeding the separation of the hyperfine lines, compared to sine-wave based modulation.	Nitrogen	36-44	spindlin 1	Homo sapiens	55-59
28607076-6	2017	In anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma (ALCL), integration of N-glycoproteomics and transcriptome sequencing revealed an ALK-regulated cytokine/receptor signaling network, including vulnerabilities corroborated by a genome-wide clustered regularly interspaced short palindromic screen.	Nitrogen	100-101	ALK receptor tyrosine kinase	Homo sapiens	40-43
28607076-6	2017	In anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma (ALCL), integration of N-glycoproteomics and transcriptome sequencing revealed an ALK-regulated cytokine/receptor signaling network, including vulnerabilities corroborated by a genome-wide clustered regularly interspaced short palindromic screen.	Nitrogen	100-101	ALK receptor tyrosine kinase	Homo sapiens	159-162
31294170-0	2017	Natural rhizobial diversity helps to reveal genes and QTLs associated with biological nitrogen fixation in common bean.	Nitrogen	86-94	brain expressed associated with NEDD4 1	Homo sapiens	114-118
31294170-3	2017	As a result, common bean is very inefficient for symbiotic nitrogen fixation, and nitrogen has to be supplied with chemical fertilizers.	Nitrogen	59-67	brain expressed associated with NEDD4 1	Homo sapiens	20-24
31294170-8	2017	Another way to discover adaptive genes is to use association genetics to identify loci that common bean plants use for enhanced biological nitrogen fixation and, in consequence, for marker assisted selection for genetic improvement of symbiotic nitrogen fixation.	Nitrogen	139-147	brain expressed associated with NEDD4 1	Homo sapiens	99-103
31294170-8	2017	Another way to discover adaptive genes is to use association genetics to identify loci that common bean plants use for enhanced biological nitrogen fixation and, in consequence, for marker assisted selection for genetic improvement of symbiotic nitrogen fixation.	Nitrogen	245-253	brain expressed associated with NEDD4 1	Homo sapiens	99-103
25990584-1	2015	The study showed that the open water of the Bothnian Sea (BS) is likely to have shifted from altering nitrogen and phosphorous limitations of the spring bloom to more nitrogen-limited conditions during the last 20 years.	Nitrogen	167-175	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	53-56
25891019-0	2015	Isoenzyme- and allozyme-specific inhibitors: 2,2"-dihydroxybenzophenones and their carbonyl N-analogues that discriminate between human glutathione transferase A1-1 and P1-1 allozymes.	Nitrogen	92-93	endonuclease, poly(U) specific	Homo sapiens	136-173
28336547-3	2017	Mutagenesis-induced disruption of the individual N-glycosylation site N50, which is highly conserved among mammals, was detected to significantly enhance the PEPT1-mediated inward transport of peptides.	Nitrogen	49-50	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	158-163
25891019-1	2015	The selectivity of certain benzophenones and their carbonyl N-analogues was investigated towards the human GSTP1-1 allozymes A, B and C involved in MDR.	Nitrogen	60-61	glutathione S-transferase pi 1	Homo sapiens	107-114
27864899-0	2017	N-Glycosylation at Asn 402 Stabilizes N-Cadherin and Promotes Cell-Cell Adhesion of Glioma Cells.	Nitrogen	0-1	cadherin 2	Homo sapiens	38-48
26333687-0	2015	Nuclear Gln3 Import Is Regulated by Nitrogen Catabolite Repression Whereas Export Is Specifically Regulated by Glutamine.	Nitrogen	36-44	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	8-12
27864899-1	2017	Cadherin is crucial for cell-cell adhesion and N-glycosylation of N-cadherin has been implicated in the process of mammary, renal, and ovarian carcinogenesis.	Nitrogen	47-48	cadherin 2	Homo sapiens	66-76
27864899-2	2017	However, whether N-glycosylation of N-cadherin plays a role in glioma remains unknown.	Nitrogen	17-18	cadherin 2	Homo sapiens	36-46
27864899-3	2017	Previous studies had indicated that N-glycosylation could occur at three asparagine residues of N-cadherin.	Nitrogen	36-37	cadherin 2	Homo sapiens	96-106
26333687-1	2015	Gln3, a transcription activator mediating nitrogen-responsive gene expression in Saccharomyces cerevisiae, is sequestered in the cytoplasm, thereby minimizing nitrogen catabolite repression (NCR)-sensitive transcription when cells are grown in nitrogen-rich environments.	Nitrogen	42-50	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
28452486-2	2017	Herein, we demonstrate a facile synthetic route to fabricate cobalt and nitrogen codoped carbon nanopolyhedra with hierarchically porous structure (Co,N-HCNP) by one-step carbonization of core-shell structured ZIF-8@ZIF-67 crystals.	Nitrogen	72-80	XPA binding protein 2	Homo sapiens	153-157
26333687-1	2015	Gln3, a transcription activator mediating nitrogen-responsive gene expression in Saccharomyces cerevisiae, is sequestered in the cytoplasm, thereby minimizing nitrogen catabolite repression (NCR)-sensitive transcription when cells are grown in nitrogen-rich environments.	Nitrogen	159-167	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
26333687-1	2015	Gln3, a transcription activator mediating nitrogen-responsive gene expression in Saccharomyces cerevisiae, is sequestered in the cytoplasm, thereby minimizing nitrogen catabolite repression (NCR)-sensitive transcription when cells are grown in nitrogen-rich environments.	Nitrogen	159-167	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
26333687-2	2015	In the face of adverse nitrogen supplies, Gln3 relocates to the nucleus and activates transcription of the NCR-sensitive regulon whose products transport and degrade a variety of poorly used nitrogen sources, thus expanding the cell"s nitrogen-acquisition capability.	Nitrogen	23-31	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
27496791-9	2017	Pearson correlation analysis revealed a positive relation of serum chemerin concentrations with body mass index, systolic blood pressure, diastolic blood pressure, triglycerides, low-density lipoprotein cholesterol, blood urea nitrogen, creatinine, C-reactive protein and left atrial diameter.	Nitrogen	227-235	retinoic acid receptor responder 2	Homo sapiens	67-75
26333687-2	2015	In the face of adverse nitrogen supplies, Gln3 relocates to the nucleus and activates transcription of the NCR-sensitive regulon whose products transport and degrade a variety of poorly used nitrogen sources, thus expanding the cell"s nitrogen-acquisition capability.	Nitrogen	191-199	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
26333687-2	2015	In the face of adverse nitrogen supplies, Gln3 relocates to the nucleus and activates transcription of the NCR-sensitive regulon whose products transport and degrade a variety of poorly used nitrogen sources, thus expanding the cell"s nitrogen-acquisition capability.	Nitrogen	191-199	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
26333687-3	2015	Rapamycin also elicits nuclear Gln3 localization, implicating Target-of-rapamycin Complex 1 (TorC1) in nitrogen-responsive Gln3 regulation.	Nitrogen	103-111	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	31-35
26333687-3	2015	Rapamycin also elicits nuclear Gln3 localization, implicating Target-of-rapamycin Complex 1 (TorC1) in nitrogen-responsive Gln3 regulation.	Nitrogen	103-111	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	123-127
28430139-6	2017	Downregulation of ADAM28 with siRNA technology resulted in a lack of weight gain, promotion of insulin sensitivity/glucose tolerance and decreased liver tumour necrosis factor-alpha (TNF-alpha) levels in our diet-induced obesity mouse model as well as reduced blood urea nitrogen, alkaline phosphatase and aspartate aminotransferase.	Nitrogen	271-279	a disintegrin and metallopeptidase domain 28	Mus musculus	18-24
28430139-7	2017	In addition, we show that ADAM28 knock-out mice also displayed reduced body weight, elevated high density lipoprotein cholesterol levels, and reductions in blood urea nitrogen, alkaline phosphatase, and aspartate aminotransferase.	Nitrogen	167-175	a disintegrin and metallopeptidase domain 28	Mus musculus	26-32
28323432-5	2017	The nitrogen-sulfur link in CF3NSF2 was revealed to be predominantly ionic CF3N--+SF2 in structure rather than the conventional N S double bond on the basis of natural bond orbital analysis.	Nitrogen	4-12	serine and arginine rich splicing factor 1	Homo sapiens	32-35
26333687-6	2015	Nuclear Gln3 entry is regulated by the cell"s overall nitrogen supply, i.e., by NCR, as long accepted.	Nitrogen	54-62	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	8-12
26333687-8	2015	When glutamine levels are high, e.g., glutamine or ammonia as the sole nitrogen source or addition of glutamine analogues, Gln3 can exit from the nucleus without binding to DNA.	Nitrogen	71-79	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	123-127
28457318-12	2017	CONCLUSIONS: Short-term, high-dose n-3 PUFA supplementation increases the omega-3 index to a greater extent in patients with a lower body mass index and higher total and low-density lipoprotein cholesterol levels.	Nitrogen	35-36	pumilio RNA binding family member 3	Homo sapiens	39-43
26333687-9	2015	In contrast, when glutamine levels are lowered, e.g., adding additional nitrogen sources to glutamine-grown cells or providing repressive nonglutamine nitrogen sources, Gln3 export does not occur in the absence of DNA binding.	Nitrogen	72-80	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	169-173
26395994-7	2015	Changes at N-glycosylation motifs were also detected in IL-1, IL-10, IL-12B and IL-15.	Nitrogen	11-12	interleukin-15	Oryctolagus cuniculus	80-85
28348411-0	2017	Global site-specific N-glycosylation analysis of HIV envelope glycoprotein.	Nitrogen	21-22	endogenous retrovirus group K member 20	Homo sapiens	53-74
26475191-0	2015	Possible role of glutamine synthetase of the prokaryotic type (GSI-like) in nitrogen signaling in Medicago truncatula.	Nitrogen	76-84	LOC11405318	Medicago truncatula	17-37
28221766-0	2017	Proteoform Profile Mapping of the Human Serum Complement Component C9 Revealing Unexpected New Features of N-, O-, and C-Glycosylation.	Nitrogen	91-92	complement C9	Homo sapiens	46-69
26537340-7	2015	However, animals with conditional deletion of Jagged1 did develop focal kidney fibrosis and elevated blood urea nitrogen.	Nitrogen	112-120	jagged canonical Notch ligand 1	Homo sapiens	46-53
28298102-1	2017	Rotational spectra of two nitrogen containing six-membered heterocycles which are commonly used in syntheses of pharmaceuticals, namely, N-methyl-3-piperidinol (NMP3) and N-methyl-4-piperidinol (NMP4), were measured using a broadband chirped pulse and a cavity based Fourier transform microwave spectrometer.	Nitrogen	26-34	zinc finger protein 384	Homo sapiens	195-199
27572525-5	2016	RESULTS: Results indicate that LBP treatment improved sperm density, sperm movement, the rate of normal sperm morphology, and protein expression and superoxide dismutase activity in the testes of the mice and decreased the nitrate nitrogen level in the testes of the mice.	Nitrogen	231-239	lipopolysaccharide binding protein	Mus musculus	31-34
26285173-8	2015	The effects of 2-DG on tube formation, MMP-2 activity, and VEGFR2 protein expression in HUVECs were reversed by mannose, an N-linked glycosylation precursor.	Nitrogen	124-125	kinase insert domain receptor	Rattus norvegicus	59-65
27582100-4	2016	Serum creatinine, blood urea nitrogen (BUN) level, and renal tubular injury score were significantly increased in CD4creIKK2f/f (CD4xIKK2Delta) and CD4creNEMOf/f (CD4xNEMODelta) mice compared with CD4cre mice after IRI induction.	Nitrogen	29-37	CD4 antigen	Mus musculus	114-117
26455908-0	2016	Downregulation of nitrogen permease regulator like-2 activates PDK1-AKT1 and contributes to the malignant growth of glioma cells.	Nitrogen	18-26	pyruvate dehydrogenase kinase 1	Homo sapiens	63-67
26455908-1	2016	Nitrogen permease regulator like-2(NPRL2) is a candidate tumor suppressor gene(TSG) located on chromosome 3p21.3 and deletions frequently occur in this region, leading to canceration.	Nitrogen	0-8	twisted gastrulation BMP signaling modulator 1	Homo sapiens	79-82
28104755-0	2017	N-glycosylation of human sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is essential for stability, secretion and activity.	Nitrogen	0-1	sphingomyelin phosphodiesterase acid like 3A	Homo sapiens	25-69
28104755-0	2017	N-glycosylation of human sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is essential for stability, secretion and activity.	Nitrogen	0-1	sphingomyelin phosphodiesterase acid like 3A	Homo sapiens	71-78
28104755-5	2017	Here, we investigate the roles of N-glycosylation in the expression, secretion and activity of human SMPDL3A, using inhibitors of N-glycosylation and site-directed mutagenesis, with either THP-1 macrophages or CHO cells expressing human SMPDL3A.	Nitrogen	34-35	sphingomyelin phosphodiesterase acid like 3A	Homo sapiens	101-108
28104755-9	2017	Site-directed mutagenesis of individual N-glycosylation sites in SMPDL3A identified glycosylation of Asn69 and Asn222 as affecting maturation of its N-glycans and secretion.	Nitrogen	40-41	sphingomyelin phosphodiesterase acid like 3A	Homo sapiens	65-72
28104755-12	2017	In conclusion, site-specific N-glycosylation is essential for the intracellular stability, secretion and activity of human SMPDL3A.	Nitrogen	29-30	sphingomyelin phosphodiesterase acid like 3A	Homo sapiens	123-130
26285173-10	2015	SIGNIFICANCE: This ex vivo and in vitro study demonstrates that 2-DG inhibits angiogenesis with an action involving attenuation of VEGFR2 signaling and MMP-2 expression, possibly resulting from interference with N-linked glycosylation of VEGFR2.	Nitrogen	3-4	kinase insert domain receptor	Rattus norvegicus	131-137
28151664-2	2017	The reactions of N-tethered 1,6-diynes with N3-benzoylthymine, N4,N4-bis(Boc)cytosine, N3-benzoyluracil and N6,N6-bis(Boc)adenine exclusively afforded the pyrrolylmethyl and furylmethyl nucleotides in good yields.	Nitrogen	17-18	BOC cell adhesion associated, oncogene regulated	Homo sapiens	73-76
28151664-2	2017	The reactions of N-tethered 1,6-diynes with N3-benzoylthymine, N4,N4-bis(Boc)cytosine, N3-benzoyluracil and N6,N6-bis(Boc)adenine exclusively afforded the pyrrolylmethyl and furylmethyl nucleotides in good yields.	Nitrogen	17-18	BOC cell adhesion associated, oncogene regulated	Homo sapiens	118-121
27526040-11	2016	The most active compound 14i might be used as the lead compound for further structure modification of the new low molecular weight PTP1B inhibitors with the N-containing heterocyclic skeleton.	Nitrogen	157-158	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	131-136
26285173-11	2015	Further studies are needed to show that 2-DG inhibits VEGF-mediated angiogenesis or that the actual status of N-glycosylation of VEGFR2 is affected by the treatment.	Nitrogen	110-111	kinase insert domain receptor	Rattus norvegicus	129-135
27596261-7	2016	These findings indicate that feeding of n-3 PUFA enriched diet increased IGF-1 and testosterone secretion, reduced pubertal age and improved both fresh and post-thawing semen quality in male buffalo.	Nitrogen	8-9	PUFA	Bos taurus	44-48
28186505-0	2017	N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death.	Nitrogen	0-1	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	25-30
28186505-2	2017	We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans.	Nitrogen	25-26	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	101-106
28186505-2	2017	We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans.	Nitrogen	25-26	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	129-134
28186505-2	2017	We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans.	Nitrogen	49-50	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	101-106
28186505-2	2017	We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans.	Nitrogen	49-50	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	129-134
28186505-7	2017	Altogether our findings demonstrate that N-glyc of TRAIL-R1 promotes TRAIL signaling and restricts virus-mediated inhibition.	Nitrogen	41-42	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	51-56
28186505-7	2017	Altogether our findings demonstrate that N-glyc of TRAIL-R1 promotes TRAIL signaling and restricts virus-mediated inhibition.	Nitrogen	41-42	tumor necrosis factor (ligand) superfamily, member 10	Mus musculus	69-74
28296334-4	2017	The extent of N-demethylation of amitriptyline significantly decreased in subjects carrying two nonfunctional alleles of CYP2C19.	Nitrogen	14-15	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	121-128
27457784-9	2016	Further, incubations of M11 with recombinant P450s showed that M12 is formed via N-dealkylation of M11 by CYP3A4, CYP2C19, and CYP1A2.	Nitrogen	81-82	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	114-121
27434063-0	2016	High-Spin Iron(I) and Iron(0) Dinitrogen Complexes Supported by N-Heterocyclic Carbene Ligands.	Nitrogen	30-40	spindlin 1	Homo sapiens	5-9
27434063-1	2016	The use of 1,3-dicyclohexylimidazol-2-ylidene (ICy) as ligand has enabled the preparation of the high-spin tetrahedral iron(I)- and iron(0)-N2 complexes, namely [(ICy)3 Fe(N2 )][BPh4 ] (1) and [(ICy)3 Fe(N2 )] (2), the electronic structures of which have been established by various spectroscopic characterization and DFT calculations.	Nitrogen	140-142	spindlin 1	Homo sapiens	102-106
26439012-2	2015	Previous studies have shown that nitrogen and amino acid signals activate TORC1 via the small GTPases, Gtr1/2.	Nitrogen	33-41	Rag GTPase GTR1	Saccharomyces cerevisiae S288C	103-109
27293214-9	2016	Hcy-thiolactone (free, derived from total Hcy, or from MUP-bound N-linked or S-linked Hcy) is separated by a cation exchange high-performance liquid chromatography, post-column derivatized with o-phthaldialdehyde, and quantified by fluorescence.	Nitrogen	65-66	major urinary protein 21	Mus musculus	55-58
27318934-5	2016	The kidney-targeted CBA-PSGT-delivered HGF also strikingly reduced various pathologic and molecular markers in vivo such as the level of collagens (type I and II), blood urea nitrogen (BUN), creatinine, and the expressions of ICAM-1, TIMP-1 and alpha-SMA which play a critical role in obstructive kidney functions.	Nitrogen	175-183	hepatocyte growth factor	Rattus norvegicus	39-42
27455833-7	2016	It is found that the tautomer where hydroxyl groups are syn to nitrogen of isoindoline ring is most stable and thus, responsible for the ESIPT process.	Nitrogen	63-71	synemin	Homo sapiens	56-59
26976902-5	2016	Addition of SFM and RB to the RD in Exp.1 linearly decreased (P &lt; 0.01) the digestibility coefficients of DM, energy, ileal digestible energy (IDE), metabolizability coefficients of DM, nitrogen (N), energy, N correct energy, metabolize energy (ME), and nitrogen-corrected ME.	Nitrogen	189-197	alpha expansin 1	Zea mays	36-41
26976902-5	2016	Addition of SFM and RB to the RD in Exp.1 linearly decreased (P &lt; 0.01) the digestibility coefficients of DM, energy, ileal digestible energy (IDE), metabolizability coefficients of DM, nitrogen (N), energy, N correct energy, metabolize energy (ME), and nitrogen-corrected ME.	Nitrogen	257-265	alpha expansin 1	Zea mays	36-41
27343616-5	2016	Furthermore, Sil@Poly(THMA-co-MBAAm) was also applied for the N-glycosylation sites profiling towards the digests of the mouse brain, and 1997N-glycosylated peptides were identified, corresponding to 686 glycoprotein groups.	Nitrogen	62-63	Scl/Tal1 interrupting locus	Mus musculus	13-16
27132228-2	2016	Different carbon and nitrogen ratios have shown different growth rates and biomass productivity and C:N ratio 50:10 as mgL(-1) has shown the best production than all.	Nitrogen	102-103	LLGL scribble cell polarity complex component 1	Homo sapiens	119-125
27261458-0	2016	Nitrogen Starvation-induced Phosphorylation of Ras1 Protein and Its Potential Role in Nutrient Signaling and Stress Response.	Nitrogen	0-8	Ras family GTPase RAS1	Saccharomyces cerevisiae S288C	47-51
27261458-5	2016	Likewise, subjecting cells to nitrogen starvation also elevates the level of Ras1 phosphorylation.	Nitrogen	30-38	Ras family GTPase RAS1	Saccharomyces cerevisiae S288C	77-81
27486435-4	2016	To answer these questions, we developed an approach that capitalizes on the specificity of bacterial biotin ligase, which adds biotin to lysine in a short acceptor peptide sequence; the distinct mobility of MRAP protomers of opposite orientations based on their N-linked glycosylation; and the ease of identifying biotin-labeled proteins.	Nitrogen	262-263	melanocortin-2 receptor accessory protein	Cricetulus griseus	207-211
27325772-0	2016	Arabidopsis cryptochrome 1 functions in nitrogen regulation of flowering.	Nitrogen	40-48	cryptochrome 1	Arabidopsis thaliana	12-26
27135698-8	2016	The photolytic rate of BDE-153 in oxygen-rich (aerated) solution was much slower than in oxygen-poor (nitrogen-sparged) conditions, demonstrating that (3)NOM* is a more effective reagent for degradation of BDE-153 than (1)O2.	Nitrogen	102-110	homeobox D13	Homo sapiens	23-26
27729721-1	2016	Uroporphyrinogen III methyl transferase (UPM1) and Sirohydrochlorin ferrochelatase (SIRB) are the important genes involved in the biosynthesis of siroheme, the prosthetic group of nitrite reductases (NiR) and sulfite reductases (SiR) involved in nitrogen and sulfur assimilation.	Nitrogen	246-254	urophorphyrin methylase 1	Arabidopsis thaliana	41-45
27729721-1	2016	Uroporphyrinogen III methyl transferase (UPM1) and Sirohydrochlorin ferrochelatase (SIRB) are the important genes involved in the biosynthesis of siroheme, the prosthetic group of nitrite reductases (NiR) and sulfite reductases (SiR) involved in nitrogen and sulfur assimilation.	Nitrogen	246-254	sirohydrochlorin ferrochelatase B	Arabidopsis thaliana	84-88
27314333-4	2016	Using chemical inhibitors, deglycosylase and site-directed mutagenesis, we found that human Rspo1 and Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosylated at N160, a position near the N-terminus of TSR1 domain.	Nitrogen	117-118	R-spondin 3	Homo sapiens	102-107
27314333-4	2016	Using chemical inhibitors, deglycosylase and site-directed mutagenesis, we found that human Rspo1 and Rspo3 are both N-glycosylated at N137, a site near the C-terminus of the furin repeat 2 domain, and Rspo2 is N-glycosylated at N160, a position near the N-terminus of TSR1 domain.	Nitrogen	135-136	R-spondin 3	Homo sapiens	102-107
27281343-0	2016	Regulation of the Axillary Osmidrosis-Associated ABCC11 Protein Stability by N-Linked Glycosylation: Effect of Glucose Condition.	Nitrogen	77-78	ATP binding cassette subfamily C member 11	Homo sapiens	49-55
27281343-4	2016	However, little is known about the role of N-linked glycosylation in the regulation of ABCC11 protein.	Nitrogen	43-44	ATP binding cassette subfamily C member 11	Homo sapiens	87-93
27281343-5	2016	In the current study, we investigated the effects of N-linked glycosylation on the protein level and localization of ABCC11 using polarized Madin-Darby canine kidney II cells.	Nitrogen	53-54	ATP binding cassette subfamily C member 11	Canis lupus familiaris	117-123
27281343-6	2016	When the N-linked glycosylation in ABCC11-expressing cells was chemically inhibited by tunicamycin treatment, the maturation of ABCC11 was suppressed and its protein level was significantly decreased.	Nitrogen	9-10	ATP binding cassette subfamily C member 11	Homo sapiens	35-41
27281343-6	2016	When the N-linked glycosylation in ABCC11-expressing cells was chemically inhibited by tunicamycin treatment, the maturation of ABCC11 was suppressed and its protein level was significantly decreased.	Nitrogen	9-10	ATP binding cassette subfamily C member 11	Homo sapiens	128-134
27281343-11	2016	These results suggest that N-linked glycosylation is important for the protein stability of ABCC11, and physiological alteration in glucose may affect the ABCC11 protein level and ABCC11-related phenotypes in humans, such as axillary osmidrosis.	Nitrogen	27-28	ATP binding cassette subfamily C member 11	Homo sapiens	92-98
27281343-11	2016	These results suggest that N-linked glycosylation is important for the protein stability of ABCC11, and physiological alteration in glucose may affect the ABCC11 protein level and ABCC11-related phenotypes in humans, such as axillary osmidrosis.	Nitrogen	27-28	ATP binding cassette subfamily C member 11	Homo sapiens	155-161
27281343-11	2016	These results suggest that N-linked glycosylation is important for the protein stability of ABCC11, and physiological alteration in glucose may affect the ABCC11 protein level and ABCC11-related phenotypes in humans, such as axillary osmidrosis.	Nitrogen	27-28	ATP binding cassette subfamily C member 11	Homo sapiens	155-161
27151646-0	2016	The role of N-glycosylation in high glucose-induced upregulation of intercellular adhesion molecule-1 on bovine retinal endothelial cells.	Nitrogen	12-13	intercellular adhesion molecule 1	Bos taurus	68-101
27151646-2	2016	Given the role of the intercellular adhesion molecule-1 (ICAM-1) in inflammation, the potential effect of N-glycosylation on the upregulated expression of ICAM-1 at the surface of bovine retinal endothelial cells (BRECs) induced by high glucose concentrations was investigated.	Nitrogen	106-107	intercellular adhesion molecule 1	Bos taurus	155-161
27234584-5	2016	It is interesting that the catalytic sites of MMPs do not contain O-linked glycans, but instead possess a conserved N-linked glycosylation site.	Nitrogen	116-117	matrix metallopeptidase 9	Homo sapiens	46-50
26957519-4	2016	Growth on D-serine as the sole source of nitrogen was retained in the  dsdA mutant and was abolished completely in the  dadA and  dadA- dsdA mutants.	Nitrogen	41-49	D-serine dehydratase	Pseudomonas aeruginosa PAO1	71-75
26957519-4	2016	Growth on D-serine as the sole source of nitrogen was retained in the  dsdA mutant and was abolished completely in the  dadA and  dadA- dsdA mutants.	Nitrogen	41-49	D-serine dehydratase	Pseudomonas aeruginosa PAO1	136-140
26957519-5	2016	However, when complemented by dsdA on a plasmid, the double mutant was able to grow on D-serine as the sole source of carbon and nitrogen, supporting the proposed biochemical function of DsdA in the conversion of D-serine into pyruvate and ammonia.	Nitrogen	129-137	D-serine dehydratase	Pseudomonas aeruginosa PAO1	30-34
27053713-1	2016	The most common congenital disorder of glycosylation (CDG), phosphomannomutase 2 (PMM2)-CDG, is caused by mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.	Nitrogen	191-192	phosphomannomutase 2	Homo sapiens	60-80
27053713-1	2016	The most common congenital disorder of glycosylation (CDG), phosphomannomutase 2 (PMM2)-CDG, is caused by mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.	Nitrogen	191-192	phosphomannomutase 2	Homo sapiens	82-86
27053713-1	2016	The most common congenital disorder of glycosylation (CDG), phosphomannomutase 2 (PMM2)-CDG, is caused by mutations in PMM2 that limit availability of mannose precursors required for protein N-glycosylation.	Nitrogen	191-192	phosphomannomutase 2	Homo sapiens	119-123
27208309-10	2016	Similar to Arabidopsis, we found that mutation of the BT1/BT2 ortholog gene in rice (Oryza sativa) OsBT increased NUE by 20% compared to wild-type rice plants under low nitrogen conditions.	Nitrogen	169-177	BTB and TAZ domain protein 2	Arabidopsis thaliana	58-61
27233360-11	2016	Increased level of urea, creatinine, bilirubin, blood urea nitrogen whereas decreased concentration of proteins in serum of CCl4 treated animals were restored towards the normal level with co-administration of ASM.	Nitrogen	59-67	H19, imprinted maternally expressed transcript (non-protein coding)	Rattus norvegicus	210-213
27227887-5	2016	These phenotypes were rescued by TORC1 inhibition using pharmacological or genetic means, and the loss of Lam2, Gtr1, Gtr2, Npr2 or Npr3 disinhibited TORC1 activity under nitrogen depletion, as measured by Rps6 phosphorylation.	Nitrogen	171-179	Gtr2p	Saccharomyces cerevisiae S288C	118-122
27227887-5	2016	These phenotypes were rescued by TORC1 inhibition using pharmacological or genetic means, and the loss of Lam2, Gtr1, Gtr2, Npr2 or Npr3 disinhibited TORC1 activity under nitrogen depletion, as measured by Rps6 phosphorylation.	Nitrogen	171-179	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	124-128
27062461-0	2016	Addition Reactions of Me3 SiCN with Aldehydes Catalyzed by Aluminum Complexes Containing in their Coordination Sphere O, S, and N Ligands.	Nitrogen	29-30	malic enzyme 3	Homo sapiens	22-25
27187489-8	2016	This review explores the present knowledge about these mechanisms, in order to propose a scheme of distribution of reductants produced by G6PDH during nitrogen assimilation and stress.	Nitrogen	151-159	glucose-6-phosphate dehydrogenase	Homo sapiens	138-143
27200068-3	2016	As a legume, common bean also has the economic and environmental benefit of associating with nitrogen-fixing bacteria, thus reducing the use of synthetic fertilizers, which is key for sustainable agriculture.	Nitrogen	93-101	brain expressed associated with NEDD4 1	Homo sapiens	20-24
26736052-2	2016	Nitrogen (N), which is an environmental sensitivity element, is largely retained in AMFR samples derived from fermentation substrates.	Nitrogen	0-8	autocrine motility factor receptor	Homo sapiens	84-88
26736052-6	2016	In the AMFR sample, organic amine-N, pyrrolic-N, protein-N, pyridinic-N, was the main N-containing species.	Nitrogen	34-35	autocrine motility factor receptor	Homo sapiens	7-11
26736052-11	2016	N-containing organic compounds, including amine-N, nitrile-N and heterocyclic-N, were discerned from the AMFR pyrolysis process.	Nitrogen	0-1	autocrine motility factor receptor	Homo sapiens	105-109
26785728-7	2016	By multiplexed capillary gel electrophoresis coupled to laser induced fluorescence detection (xCGE-LIF) we could show that PMM2-iPSC-C3 exhibit the common hPSC N-glycosylation pattern with high-mannose-type N-glycans as the predominant species.	Nitrogen	160-161	phosphomannomutase 2	Homo sapiens	123-127
26785728-9	2016	In addition, quantitative assessment of N-glycosylation by xCGE-LIF showed an up to 40% reduction of high-mannose-type N-glycans in PMM2-iPSC-C3, which was in concordance to the observed reduction of the Glc3Man9GlcNAc2 lipid-linked oligosaccharide compared with control hPSCs.	Nitrogen	40-41	phosphomannomutase 2	Homo sapiens	132-136
26785728-10	2016	Thus we could model the PMM2-CDG disease phenotype of hypoglycosylation with patient derived iPSCsin vitro Knock-down ofPMM2by shRNA in PMM2-iPSC-C3 led to a residual activity of 5% and to a further reduction of the level of N-glycosylation.	Nitrogen	130-131	phosphomannomutase 2	Homo sapiens	24-28
26858365-4	2016	N deprivation elicited a doubling of the rate of NDA2-dependent CEF, with little contribution from PGR5/PGRL1-dependent CEF The H(+) gradient generated by CEF is essential to sustain nonphotochemical quenching, while an increase in the level of reduced plastoquinone would promote a state transition; both are necessary to down-regulate photosystem II activity.	Nitrogen	0-1	uncharacterized protein	Chlamydomonas reinhardtii	49-53
26888522-10	2016	The supramolecular interactions of Ag with different moieties of N in N-GrAg were evidenced by IR, (13)C NMR and XPS analyses, which resulted in the enhancement of its surface area and electrical conductivity as compared to that of N-Gr.	Nitrogen	65-66	reticulon 4 receptor	Homo sapiens	70-74
26824300-3	2016	The N-hydroxylated metabolites of many AAs also can undergo a co-oxidation reaction with oxy-hemolgobin (HbO2) to form methemoglobin (met-Hb) and the arylnitroso intermediates, which react with the beta-Cys(93) chain of Hb to form Hb-arylsulfinamide adducts.	Nitrogen	4-5	hemoglobin subunit gamma 2	Homo sapiens	119-132
27136847-5	2016	Under these laser operation conditions and a gas pressure of 1000 mbar a limit of detection (3sigma) of 1.5 ppmv for hydrogen sulfide (H&lt;sub&gt;2&lt;/sub&gt;S) in nitrogen was achieved using a 100 m Herriott cell and a thermoelectric cooled MCT detector for absorption measurements.	Nitrogen	166-174	Leucine transport, high	Homo sapiens	135-139
26856397-5	2016	Olanzapine N-demethylation and N-oxygenation were found to be catalyzed by CYP1A2 and CYP2D6 and by CYP2D6 and FMO3, respectively, in experiments using liver microsomes and recombinant enzymes.	Nitrogen	11-12	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	111-115
27110058-3	2016	The expression of three genes, TaASN1-3, was studied in different tissues and in response to nitrogen and sulphur supply.	Nitrogen	93-101	asparagine synthetase [glutamine-hydrolyzing]	Triticum aestivum	31-39
27110058-6	2016	However, only TaASN1 was affected by nitrogen or sulphur supply in pot-based experiments, showing complex tissue-specific and developmentally-changing responses.	Nitrogen	37-45	asparagine synthetase [glutamine-hydrolyzing]	Triticum aestivum	14-20
26938549-5	2016	These results suggest that N-linked glycosylation of human BST-2 is dispensable for intracellular virion retention and imply that this recently discovered intracellular tethering function may be evolutionarily distinguished from the canonical antiviral function of BST-2 by tethering nascent virions at the cell surface.	Nitrogen	27-28	bone marrow stromal cell antigen 2	Homo sapiens	59-64
26896178-5	2016	In the present study, we produced soluble ActRIIB-2a in P. pastoris, and showed that it is N-glycosylated, similar to soluble ActRIIB-1.	Nitrogen	91-92	activin A receptor type 2B	Homo sapiens	42-49
26059044-4	2016	In this study, we transiently expressed human IL-22 in Nicotiana benthamiana plants and investigated the role of N-glycosylation on protein folding and biological activity.	Nitrogen	55-56	interleukin 22	Homo sapiens	46-51
26858738-5	2016	Mass spectrometric analysis of IgA1 glycopeptides revealed the presence of complex biantennary N-glycans with terminal N-acetylglucosamine present on the N-glycosylation site of the CH2 domain in the IgA1 alpha chain.	Nitrogen	95-96	immunoglobulin heavy constant alpha 1	Homo sapiens	31-35
26858738-5	2016	Mass spectrometric analysis of IgA1 glycopeptides revealed the presence of complex biantennary N-glycans with terminal N-acetylglucosamine present on the N-glycosylation site of the CH2 domain in the IgA1 alpha chain.	Nitrogen	95-96	immunoglobulin heavy constant alpha 1	Homo sapiens	200-204
27250875-3	2016	By deploying a genetic screen for suppressors of cell death triggered by virus-induced gene silencing of BAK1/SERK4 on Arabidopsis knockout collections, we identified STT3a, a protein involved in N-glycosylation modification, as an important regulator of bak1/serk4 cell death.	Nitrogen	196-197	staurosporin and temperature sensitive 3-like A	Arabidopsis thaliana	167-172
27250875-6	2016	Ectopic expression of CRK4 induced STT3a/N-glycosylation-dependent cell death in Arabidopsis and Nicotiana benthamiana.	Nitrogen	41-42	cysteine-rich RLK (RECEPTOR-like protein kinase) 4	Arabidopsis thaliana	22-26
26585416-0	2016	Effect of N-glycosylation on the transport activity of the peptide transporter PEPT1.	Nitrogen	10-11	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	79-84
26585416-5	2016	Putative N-glycosylation sites of mPEPT1 were altered by site-directed mutagenesis followed by expression in Xenopus laevis oocytes.	Nitrogen	9-10	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	34-40
26599428-3	2016	A similar half-sandwich type complex, [{P(6-Me-2-py)3}FeCl(OTf)] 2THF (6 2THF), is obtained from reaction of 2 with Fe(OTf)2 in the presence of LiCl, only now with all three of the N-atoms of the ligand coordinated to Fe(II).	Nitrogen	181-182	POU class 2 homeobox 2	Homo sapiens	119-124
26913555-3	2016	Pig CD90 cDNA contained an open reading frame (486 bp) encoding 161 amino acids with three putative N-glycosylation sites and four well-conserved cysteine residues, which form a possible disulfide bond within the extracellular domain among mammalian species.	Nitrogen	11-12	Thy-1 cell surface antigen	Sus scrofa	4-8
28861966-4	2016	n-BuOH fractions of Phytolacca Radix could cause intestinal edema in mice, increase the edema of duodenum, jejunum and the water content in stool, inhibit the proliferation of HT-29 cells and IEC-6 cells, indicating its intestinal toxicity, with HT-29 IC50 at 14.59 mg L-1 and IEC-6 IC50 at 43.77 mg L-1.	Nitrogen	0-1	ribosomal protein L4	Rattus norvegicus	269-287
26603934-5	2015	Biochemical characterisation of transiently expressed human CPX-1 revealed that CPX-1 was secreted in an N-glycosylation-dependent manner as treatment with the N-glycosylation inhibitor tunicamycin inhibited secretion concomitant with a reduction in CPX-1 mobility on Western blot.	Nitrogen	105-106	carboxypeptidase X, M14 family member 1	Homo sapiens	80-85
26603934-5	2015	Biochemical characterisation of transiently expressed human CPX-1 revealed that CPX-1 was secreted in an N-glycosylation-dependent manner as treatment with the N-glycosylation inhibitor tunicamycin inhibited secretion concomitant with a reduction in CPX-1 mobility on Western blot.	Nitrogen	105-106	carboxypeptidase X, M14 family member 1	Homo sapiens	80-85
26603934-5	2015	Biochemical characterisation of transiently expressed human CPX-1 revealed that CPX-1 was secreted in an N-glycosylation-dependent manner as treatment with the N-glycosylation inhibitor tunicamycin inhibited secretion concomitant with a reduction in CPX-1 mobility on Western blot.	Nitrogen	160-161	carboxypeptidase X, M14 family member 1	Homo sapiens	80-85
26603934-5	2015	Biochemical characterisation of transiently expressed human CPX-1 revealed that CPX-1 was secreted in an N-glycosylation-dependent manner as treatment with the N-glycosylation inhibitor tunicamycin inhibited secretion concomitant with a reduction in CPX-1 mobility on Western blot.	Nitrogen	160-161	carboxypeptidase X, M14 family member 1	Homo sapiens	80-85
26603934-6	2015	Using a collagen pull-down assay we found that secreted CPX-1 bound collagen and this appeared independent of N-glycosylation as treatment with PNGaseF did not affect binding.	Nitrogen	110-111	carboxypeptidase X, M14 family member 1	Homo sapiens	56-61
26568372-6	2015	This difference in the yield of H2O2 formed between the systems along with the improvements observed in terms of the oxygen reduction onset and E1/2 in the case of Fe-Fe2O3/NGr reveals the activity modulation achieved for the latter is due to the coexistence of factors such as the presence of the mixed valancies of iron nanoparticles, small size and homogeneous distribution of Fe-Fe2O3 nanoparticles and the electronic modifications induced by the doped nitrogen in NGr.	Nitrogen	457-465	reticulon 4 receptor	Homo sapiens	173-176
26568372-6	2015	This difference in the yield of H2O2 formed between the systems along with the improvements observed in terms of the oxygen reduction onset and E1/2 in the case of Fe-Fe2O3/NGr reveals the activity modulation achieved for the latter is due to the coexistence of factors such as the presence of the mixed valancies of iron nanoparticles, small size and homogeneous distribution of Fe-Fe2O3 nanoparticles and the electronic modifications induced by the doped nitrogen in NGr.	Nitrogen	457-465	reticulon 4 receptor	Homo sapiens	469-472
26483551-9	2015	Taken together, these data are the first to demonstrate that EGFR activation can be regulated by the N-glycosylation of integrin alpha5, which is a novel molecular paradigm for the cross-talk between integrins and growth factor receptors.	Nitrogen	101-102	integrin subunit alpha 5	Bos taurus	120-135
26524472-3	2015	Here, we establish that, through N-acetylation of our original peptidomimetic series, we are able to improve DOR affinity and increase selectivity relative to KOR while maintaining the desired MOR agonist/DOR antagonist profile.	Nitrogen	33-34	opioid receptor, delta 1	Mus musculus	109-112
26524472-3	2015	Here, we establish that, through N-acetylation of our original peptidomimetic series, we are able to improve DOR affinity and increase selectivity relative to KOR while maintaining the desired MOR agonist/DOR antagonist profile.	Nitrogen	33-34	opioid receptor, kappa 1	Mus musculus	159-162
26524472-3	2015	Here, we establish that, through N-acetylation of our original peptidomimetic series, we are able to improve DOR affinity and increase selectivity relative to KOR while maintaining the desired MOR agonist/DOR antagonist profile.	Nitrogen	33-34	opioid receptor, delta 1	Mus musculus	205-208
26151568-5	2015	The N-enriched CNFs and Cu nanoparticles (NPs)-doped carbon beads (N-Cu-CNF/CBs) were used for the removal of nitric oxide (NO) by reduction.	Nitrogen	4-5	NPHS1 adhesion molecule, nephrin	Homo sapiens	15-18
28243336-6	2017	Further studies showed that the regulated beta3GnT8 could convert the heterogeneous N-glycosylated forms of CD147 and change the polylactosamine structures carried on CD147.	Nitrogen	84-85	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	Homo sapiens	42-51
27966990-0	2017	Site-Specific N-Glycosylation of Endothelial Cell Receptor Tyrosine Kinase VEGFR-2.	Nitrogen	14-15	kinase insert domain receptor	Homo sapiens	75-82
27966990-2	2017	The extracellular domain of VEGFR-2 is composed of seven immunoglobulin-like domains, each with multiple potential N-glycosylation sites (sequons).	Nitrogen	115-116	kinase insert domain receptor	Homo sapiens	28-35
27966990-4	2017	However, despite its importance, the functional role of N-glycosylation of VEGFR-2 remains poorly understood.	Nitrogen	56-57	kinase insert domain receptor	Homo sapiens	75-82
27966990-5	2017	The objectives of the present study were to characterize N-glycosylation sites in VEGFR-2 via enzymatic release of the glycans and concomitant incorporation of 18O into formerly N-glycosylated sites followed by tandem mass spectrometry (MS/MS) analysis to determine N-glycosylation site occupancy and the site-specific N-glycan heterogeneity of VEGFR-2 glycopeptides.	Nitrogen	57-58	kinase insert domain receptor	Homo sapiens	82-89
27966990-5	2017	The objectives of the present study were to characterize N-glycosylation sites in VEGFR-2 via enzymatic release of the glycans and concomitant incorporation of 18O into formerly N-glycosylated sites followed by tandem mass spectrometry (MS/MS) analysis to determine N-glycosylation site occupancy and the site-specific N-glycan heterogeneity of VEGFR-2 glycopeptides.	Nitrogen	57-58	kinase insert domain receptor	Homo sapiens	345-352
27966990-5	2017	The objectives of the present study were to characterize N-glycosylation sites in VEGFR-2 via enzymatic release of the glycans and concomitant incorporation of 18O into formerly N-glycosylated sites followed by tandem mass spectrometry (MS/MS) analysis to determine N-glycosylation site occupancy and the site-specific N-glycan heterogeneity of VEGFR-2 glycopeptides.	Nitrogen	178-179	kinase insert domain receptor	Homo sapiens	82-89
27966990-5	2017	The objectives of the present study were to characterize N-glycosylation sites in VEGFR-2 via enzymatic release of the glycans and concomitant incorporation of 18O into formerly N-glycosylated sites followed by tandem mass spectrometry (MS/MS) analysis to determine N-glycosylation site occupancy and the site-specific N-glycan heterogeneity of VEGFR-2 glycopeptides.	Nitrogen	178-179	kinase insert domain receptor	Homo sapiens	82-89
27966990-6	2017	The data demonstrated that all seven VEGFR-2 immunoglobulin-like domains have at least one occupied N-glycosylation site.	Nitrogen	100-101	kinase insert domain receptor	Homo sapiens	37-44
28093152-0	2017	Re: N-Glycosylation Critically Regulates Function of Oxalate Transporter SLC26A6.	Nitrogen	4-5	solute carrier family 26 member 6	Homo sapiens	73-80
28126812-1	2017	Pentazole (HN5), an unstable molecular ring comprising five nitrogen atoms, has been of great interest to researchers for the better part of a century.	Nitrogen	60-68	MT-RNR2 like 5 (pseudogene)	Homo sapiens	11-14
28051307-0	2017	Highly Efficient Magnetic Nitrogen-Doped Porous Carbon Prepared by One-Step Carbonization Strategy for Hg2+ Removal from Water.	Nitrogen	26-34	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	103-106
27912985-7	2017	Mosquito membrane feeding assays also revealed improved functional immunogenicity of SYN Pfs48/45 (N-glycosylation sites intact) as compared to MUT1 or MUT2 Pfs48/45 DNA plasmids (all N-glycosylation sites mutated).	Nitrogen	99-100	synemin	Homo sapiens	85-88
28546823-1	2017	The objective of this study was to investigate the impact of femoral head perfusion by traditional Chinese medicine Guanxinning injection promoting blood circulation for removing blood stasis on the expression of Bcl-2 and Bax induced by liquid nitrogen freezing-mediated femoral head necrosis.	Nitrogen	245-253	BCL-2	Oryctolagus cuniculus	213-218
27882369-0	2016	Regio- and stereo-selective polymerization of 1,3-butadiene catalyzed by phosphorus-nitrogen PN3-pincer cobalt(ii) complexes.	Nitrogen	84-92	sodium voltage-gated channel alpha subunit 10	Homo sapiens	93-96
27882369-3	2016	The cobalt center is chelated by the PN3 ligand through the pyridinyl nitrogen, the pyrazol nitrogen and the phosphorus donor, with a long Co-P bond distance indicating a labile character.	Nitrogen	70-78	sodium voltage-gated channel alpha subunit 10	Homo sapiens	37-40
27882369-3	2016	The cobalt center is chelated by the PN3 ligand through the pyridinyl nitrogen, the pyrazol nitrogen and the phosphorus donor, with a long Co-P bond distance indicating a labile character.	Nitrogen	92-100	sodium voltage-gated channel alpha subunit 10	Homo sapiens	37-40
27891543-9	2016	Density functional theory calculations (B3LYP/6-31G*, LanL2DZ) determined that the structure dependence of the chromogenic behaviour of these non-vaulted and polymethylene-vaulted hydrazone complexes can be attributed to variations in the participation of neighbouring nitrogen lone pairs in the d-pi conjugation on the trans-bis(salicylaldiminato)Pt(ii) coordination platforms.	Nitrogen	269-277	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	42-45
27922051-1	2016	Urate oxidase (Uox) catalyses the first reaction of oxidative uricolysis, a three-step enzymatic pathway that allows some animals to eliminate purine nitrogen through a water-soluble compound.	Nitrogen	150-158	urate oxidase	Danio rerio	0-13
27922051-1	2016	Urate oxidase (Uox) catalyses the first reaction of oxidative uricolysis, a three-step enzymatic pathway that allows some animals to eliminate purine nitrogen through a water-soluble compound.	Nitrogen	150-158	urate oxidase	Danio rerio	15-18
27681177-0	2016	N-glycosylation critically regulates function of oxalate transporter SLC26A6.	Nitrogen	0-1	solute carrier family 26 member 6	Homo sapiens	69-76
27681177-2	2016	Previous in vitro studies have suggested that SLC26A6 is heavily N-glycosylated.	Nitrogen	65-66	solute carrier family 26 member 6	Homo sapiens	46-53
27681177-3	2016	N-linked glycosylation is known to critically affect folding, trafficking, and function in a wide variety of integral membrane proteins and could therefore potentially have a critical impact on SLC26A6 function and subsequent oxalate homeostasis.	Nitrogen	0-1	solute carrier family 26 member 6	Homo sapiens	194-201
27334720-6	2016	The IL-17A(-/-) septic mice exhibited decreased serum creatinine and blood urea nitrogen levels and an improved acute tubular necrosis score.	Nitrogen	80-88	interleukin 17A	Mus musculus	4-10
27612916-0	2016	A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity.	Nitrogen	32-33	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	7-13
27866493-1	2016	DHA is a key nutritional n-3 PUFA and needs to be supplied by the human diet.	Nitrogen	13-14	pumilio RNA binding family member 3	Homo sapiens	29-33
27541496-1	2016	MAIN CONCLUSION: AtNPF3.1 gene expression is promoted by limiting nitrogen nutrition.	Nitrogen	66-74	Major facilitator superfamily protein	Arabidopsis thaliana	17-25
27622910-2	2016	Whereas contraction of the quinolinyl portion of the scaffold or cyclization of the tertiary amido group abolished high TSPO affinity, insertion of an extra nitrogen atom into the 2-arylquinolinyl portion was effective in retaining sub-nanomolar affinity for rat TSPO, while also decreasing lipophilicity to within the moderate range deemed preferable for a PET radioligand.	Nitrogen	157-165	translocator protein	Rattus norvegicus	120-124
27654218-2	2016	The lipophilic moieties attached to the N-atom of the parent structures were delineated from the 2-[9-(4-methoxyphenyl)-9H-fluoren-9-yl]oxyethyl residue, known from a prototypic mGAT3 inhibitor.	Nitrogen	40-41	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	Mus musculus	178-183
27582391-5	2016	Removing N-glycosylation from the CD16 protein core by tunicamycin also increases the ligand binding affinity.	Nitrogen	9-10	Fc gamma receptor IIIa	Homo sapiens	34-38
27639309-4	2016	Common O- and N-glycosylated species were detected on mixed or overlapped underlying protein scaffolds in both soluble and particulate fractions of hSP.	Nitrogen	14-15	heat shock protein 90 beta family member 2, pseudogene	Homo sapiens	148-151
27452639-8	2016	GM analysis revealed that n-3 PUFA supplementation increased renal steroid hormone and proteolytic metabolite levels in PMW.	Nitrogen	4-5	pumilio RNA binding family member 3	Homo sapiens	30-34
26497729-3	2015	We first synthesize a new type of freestanding LIB anode composed of micron-sized Si (mSi) particles wrapped by giant nitrogen-doped graphene (mSi@GNG) film.	Nitrogen	118-126	phenylalkylamine Ca2+ antagonist (emopamil) binding protein	Mus musculus	143-146
26241388-2	2015	Accordingly, FDL function accounts, at least in part, for major differences in the N-glycosylation patterns of glycoproteins produced by insect and mammalian cells.	Nitrogen	83-84	fused lobes	Drosophila melanogaster	13-16
26427992-4	2015	A computational search for low energy geometries revealed that the syn isomer favors a six-membered ring hydrogen bond to nitrogen and the anti isomer favors a five-membered ring hydrogen bond to oxygen.	Nitrogen	122-130	synemin	Homo sapiens	67-70
25988789-3	2015	A series of N-substituted derivatives with various hydrophobic, acidic and basic groups were designed and synthesized to evaluate the selectivity of HN derivatives toward UGT1A1.	Nitrogen	12-13	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	171-177
27560450-5	2016	Consistently, the inhibition of the Arg/N-end rule pathway with PCA significantly elevated levels of MAPT and huntingtin aggregates, accompanied by increased numbers of LC3 and SQSTM1 puncta.	Nitrogen	40-41	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	169-172
27560450-5	2016	Consistently, the inhibition of the Arg/N-end rule pathway with PCA significantly elevated levels of MAPT and huntingtin aggregates, accompanied by increased numbers of LC3 and SQSTM1 puncta.	Nitrogen	40-41	sequestosome 1	Homo sapiens	177-183
26523591-8	2015	The STA lambs had higher ( &lt; 0.01) blood concentrations of globulin and blood urea nitrogen and lower beta-hydroxybutyrate after weaning.	Nitrogen	86-94	STA	Ovis aries	4-7
27658790-3	2016	This study presents the design and synthesis of a series of [PEG]n linked dimeric ligands of CXCR4 based on the knowledge of the homodimeric crystal structure of CXCR4 and our well established platform of chemistry and bioassays for CXCR4.	Nitrogen	16-17	C-X-C motif chemokine receptor 4	Homo sapiens	93-98
27658790-3	2016	This study presents the design and synthesis of a series of [PEG]n linked dimeric ligands of CXCR4 based on the knowledge of the homodimeric crystal structure of CXCR4 and our well established platform of chemistry and bioassays for CXCR4.	Nitrogen	16-17	C-X-C motif chemokine receptor 4	Homo sapiens	162-167
27658790-3	2016	This study presents the design and synthesis of a series of [PEG]n linked dimeric ligands of CXCR4 based on the knowledge of the homodimeric crystal structure of CXCR4 and our well established platform of chemistry and bioassays for CXCR4.	Nitrogen	16-17	C-X-C motif chemokine receptor 4	Homo sapiens	162-167
27539975-2	2016	N-linked glycosylation sites and glycoproteins in milk fat globule membrane (MFGM) fractions were investigated by combining N-glycosylated peptides enrichment and high-accuracy Q Exactive identification, to map the N-glycoproteome profiles in Holstein and Jersey cows, buffaloes, yaks, goats, camels, horses, and humans.	Nitrogen	0-1	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	50-75
26393572-7	2015	Results show that MDG-1 (300 mg/kg) significantly decreased the levels of blood glucose, triglycerides, blood urine nitrogen and albumin, and significantly inhibited the expression of transforming growth factor-beta 1 and connective tissue growth factor.	Nitrogen	116-124	DnaJ heat shock protein family (Hsp40) member B9	Mus musculus	18-23
26013584-5	2015	Introduction of an aliphatic amine chain on the N atom of the phenothiazine B ring (promazine) conferred inhibitory activity toward NOX2, NOX4, and NOX5 but not NOX1 and NOX3.	Nitrogen	48-49	cytochrome b-245 beta chain	Homo sapiens	132-136
26008190-10	2015	Genetic diversity and the presence of the nitrogen transceptor NRT1;1 explain heterogeneity in the responses of root hairs to different nitrogen forms in Arabidopsis accessions.	Nitrogen	42-50	nitrate transporter 1.1	Arabidopsis thaliana	63-67
26008190-10	2015	Genetic diversity and the presence of the nitrogen transceptor NRT1;1 explain heterogeneity in the responses of root hairs to different nitrogen forms in Arabidopsis accessions.	Nitrogen	136-144	nitrate transporter 1.1	Arabidopsis thaliana	63-67
27539975-2	2016	N-linked glycosylation sites and glycoproteins in milk fat globule membrane (MFGM) fractions were investigated by combining N-glycosylated peptides enrichment and high-accuracy Q Exactive identification, to map the N-glycoproteome profiles in Holstein and Jersey cows, buffaloes, yaks, goats, camels, horses, and humans.	Nitrogen	0-1	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	77-81
27539975-2	2016	N-linked glycosylation sites and glycoproteins in milk fat globule membrane (MFGM) fractions were investigated by combining N-glycosylated peptides enrichment and high-accuracy Q Exactive identification, to map the N-glycoproteome profiles in Holstein and Jersey cows, buffaloes, yaks, goats, camels, horses, and humans.	Nitrogen	124-125	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	50-75
27539975-2	2016	N-linked glycosylation sites and glycoproteins in milk fat globule membrane (MFGM) fractions were investigated by combining N-glycosylated peptides enrichment and high-accuracy Q Exactive identification, to map the N-glycoproteome profiles in Holstein and Jersey cows, buffaloes, yaks, goats, camels, horses, and humans.	Nitrogen	124-125	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	50-75
27539975-6	2016	N-glycosylated protein components of MFGM fractions from Holstein and Jersey cows, buffaloes, yaks, and goats were more similar to each other compared with those of camels, horses and human.	Nitrogen	0-1	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	37-41
27763330-1	2016	In P-gp-positive cell variants obtained from L1210 cells either by selection with vincristine (L1210/R) or by transfection with the human gene encoding P-gp (L1210/T), we have previously described cross-resistance to tunicamycin (TNM), a protein N-glycosylation inhibitor.	Nitrogen	231-232	phosphoglycolate phosphatase	Mus musculus	3-7
25993317-4	2015	PLA2-injected mice showed reduced levels of serum creatinine, blood urea nitrogen, renal tissue damage, and pro-inflammatory cytokine production upon cisplatin administration.	Nitrogen	73-81	phospholipase A2, group IB, pancreas	Mus musculus	0-4
26218460-4	2015	Several N-methylated analogues are selective and potent agonists or antagonists for hMC1R or hMC5R or have selective antagonist activity for hMC3R.	Nitrogen	8-9	melanocortin 5 receptor	Homo sapiens	93-98
27568658-4	2016	PS transformations of 1,6- and/or 1,7-diamino perylenes result in 2-fold annulated nitrogen-containing coronene-type molecules like anti-(ab)2-PBI 15, syn-(ab)2-PBI 16, and syn-(ab)2-PTE 18.	Nitrogen	83-91	synemin	Homo sapiens	151-154
26456786-9	2015	Using human CYPs, CYP1A2, CYP2C19, CYP2D6, and/or CYP3A4 were found to catalyze N-oxide formation and N-, O-demethylation and/or oxidation.	Nitrogen	80-81	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	18-24
27568658-4	2016	PS transformations of 1,6- and/or 1,7-diamino perylenes result in 2-fold annulated nitrogen-containing coronene-type molecules like anti-(ab)2-PBI 15, syn-(ab)2-PBI 16, and syn-(ab)2-PTE 18.	Nitrogen	83-91	synemin	Homo sapiens	173-176
27320963-0	2016	What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?	Nitrogen	46-47	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	34-38
26291458-0	2015	Functional Divergence in the Role of N-Linked Glycosylation in Smoothened Signaling.	Nitrogen	37-38	smoothened	Drosophila melanogaster	63-73
26291458-10	2015	Loss of N-glycosylation at this site disrupted Smo trafficking and attenuated its signaling capability.	Nitrogen	8-9	smoothened	Drosophila melanogaster	47-50
26609483-3	2015	There are six potential N-glycosylation sites on CD47, and glycosylation is known to be necessary for its membrane localization.	Nitrogen	24-25	CD47 molecule	Homo sapiens	49-53
27320963-3	2016	The aim of the presented study was to elucidate the contribution of human FMO3 to the N-oxygenation of selected therapeutic drugs and drugs of abuse (DOAs).	Nitrogen	86-87	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	74-78
26280490-0	2015	Development of N-(Functionalized benzoyl)-homocycloleucyl-glycinonitriles as Potent Cathepsin K Inhibitors.	Nitrogen	15-18	cathepsin K	Homo sapiens	84-95
27293214-10	2016	Using these assays with as little as 2-20 muL of urine I show that MUP carry N-linked and S-linked Hcy and that N-Hcy-MUP and S-Hcy-MUP and Hcy-thiolactone are severely elevated in cystathionine beta-synthase-deficient mice.	Nitrogen	77-78	major urinary protein 21	Mus musculus	67-70
27313224-4	2016	SV2C-LD4 exhibits the strongest protein-protein interaction and comprises five putative N-glycosylation sites (PNG sites).	Nitrogen	88-89	synaptic vesicle glycoprotein 2C	Homo sapiens	0-4
26037613-4	2015	To characterize and fully understand protein methylation, we describe here novel N-mustard analogs of S-adenosyl-l-methionine (SAM) as biochemical tools to better understand protein arginine methylation events using protein arginine methyltransferase 1 (PRMT1).	Nitrogen	81-82	protein arginine methyltransferase 1	Homo sapiens	254-259
26037613-5	2015	Specifically, azide- and alkyne-functionalized N-mustard analogs serve as cofactor mimics of SAM and are enzymatically transferred to a model peptide substrate in a PRMT1-dependent fashion.	Nitrogen	47-48	protein arginine methyltransferase 1	Homo sapiens	165-170
26280490-2	2015	Using a combination of virtual combinatorial chemistry, QSAR modeling, and molecular docking studies, a series of cathepsin K inhibitors based on N-(functionalized benzoyl)-homocycloleucyl-glycinonitrile scaffold was developed.	Nitrogen	146-148	cathepsin K	Homo sapiens	114-125
26008578-2	2015	Deletion of COQ9 results in dissociation of the CoQ-synthome, but over-expression of Coq8 putative kinase stabilizes the CoQ-synthome in the coq9 null mutant and leads to the accumulation of two nitrogen-containing Q intermediates, imino-demethoxy-Q6 (IDMQ6) and 3-hexaprenyl-4-aminophenol (4-AP) when para-aminobenzoic acid (pABA) is provided as a ring precursor.	Nitrogen	195-203	protein kinase COQ8	Saccharomyces cerevisiae S288C	85-89
25871301-1	2015	The recombination rate constants for the reactions NH2 + NH2   N2H4 (reaction k1b) and NH2 + H   NH3 (reaction k2b) with N2 as a third-body have been measured as a function of temperature and pressure.	Nitrogen	63-65	keratin 77	Homo sapiens	78-81
27486831-2	2016	These structures often differ at the C3a position, which may be substituted with an oxygen, nitrogen, or sp(3)- or sp(2)-hybridized carbon.	Nitrogen	92-100	endogenous retrovirus group K member 2	Homo sapiens	37-40
26008578-6	2015	Deletion of COQ9 in the yeast coq5-5 mutant along with Coq8 over-expression and 13C6- pABA labeling leads to the absence of 13C6-DDMQ6, and the nitrogen-containing intermediates 13C6-4-AP and 13C6-IDDMQ6 persist.	Nitrogen	144-152	protein kinase COQ8	Saccharomyces cerevisiae S288C	55-59
26008578-9	2015	These findings identify Coq9 as a multi-functional protein that is required for the function of Coq6 and Coq7 hydroxylases, for removal of the nitrogen substituent from pABA-derived Q intermediates, and is an essential component of the CoQ synthome.	Nitrogen	143-151	putative N,N-dimethylaniline monooxygenase COQ6	Saccharomyces cerevisiae S288C	96-100
25916886-1	2015	The positive electrostatic potentials (ESP) outside the sigma-hole along the extension of O P bond in O PH3 and the negative ESP outside the nitrogen atom along the extension of the C N bond in NCX could form the Group V sigma-hole interaction O PH3  NCX.	Nitrogen	141-149	T cell leukemia homeobox 2	Homo sapiens	194-197
25916886-1	2015	The positive electrostatic potentials (ESP) outside the sigma-hole along the extension of O P bond in O PH3 and the negative ESP outside the nitrogen atom along the extension of the C N bond in NCX could form the Group V sigma-hole interaction O PH3  NCX.	Nitrogen	141-149	T cell leukemia homeobox 2	Homo sapiens	251-254
26617699-7	2015	In addition, the regulated expression of GnT-V in the CNE-2R cells converted the heterogeneous N-glycosylated forms of CD147.	Nitrogen	55-56	basigin (Ok blood group)	Homo sapiens	119-124
25916886-4	2015	With the addition of X N halogen bond, the VS, min values outside the nitrogen atom of NCX becomes increasingly negative, also resulting in a stronger and more polarizable P N interaction.	Nitrogen	70-78	T cell leukemia homeobox 2	Homo sapiens	87-90
25836033-2	2015	The early stability of CSTF-2 is attributable to the influence of temperature; nevertheless, by day 405, the nitrogen removal performed by CSTF-1 increased up to similar values of CSTF-2.	Nitrogen	109-117	cleavage stimulation factor subunit 2	Homo sapiens	23-29
25836033-3	2015	The maximum total nitrogen removal efficiency was 82% in CSTF-1 and 84% in CSTF-2.	Nitrogen	18-26	cleavage stimulation factor subunit 2	Homo sapiens	75-81
25836033-4	2015	After more than 400 days of operation, CSTF-1 and CSTF-2 were capable to attain a total nitrogen removal efficiency of 74+-5% and 78+-4% with a total nitrogen conversion rate of 1.52 and 1.60kg-N/m(sponge)(3)d, respectively.	Nitrogen	88-96	cleavage stimulation factor subunit 2	Homo sapiens	50-56
25836033-4	2015	After more than 400 days of operation, CSTF-1 and CSTF-2 were capable to attain a total nitrogen removal efficiency of 74+-5% and 78+-4% with a total nitrogen conversion rate of 1.52 and 1.60kg-N/m(sponge)(3)d, respectively.	Nitrogen	150-158	cleavage stimulation factor subunit 2	Homo sapiens	50-56
25924954-0	2015	Cleavage of a P-N Bond in a Urea-Containing (Ph2 P(R)PPh2 )-Bridged Dinuclear Gold(I) Thiolate Complex by Fluoride and a Mechanistic Insight.	Nitrogen	16-17	relaxin 2	Homo sapiens	45-57
27437559-3	2016	In Et2O, 2 equiv of RLi add to both nitrogens of halodiazirine N N bond, affording N,N"-dialkylbenzamidines.	Nitrogen	36-45	ATP binding cassette subfamily E member 1	Homo sapiens	20-23
27187567-3	2016	The results showed that the maximum biomass concentration obtained in the AEM-PBR under continuous supply of nitrogen at an average rate of 19.0mgN/L/d was 2.98g/L, which was 129.2% higher than that (1.30g/L) in a PBR with all the nitrogen supplied in batch at initial.	Nitrogen	109-117	translocator protein	Homo sapiens	78-81
27187567-3	2016	The results showed that the maximum biomass concentration obtained in the AEM-PBR under continuous supply of nitrogen at an average rate of 19.0mgN/L/d was 2.98g/L, which was 129.2% higher than that (1.30g/L) in a PBR with all the nitrogen supplied in batch at initial.	Nitrogen	109-117	translocator protein	Homo sapiens	214-217
27187567-3	2016	The results showed that the maximum biomass concentration obtained in the AEM-PBR under continuous supply of nitrogen at an average rate of 19.0mgN/L/d was 2.98g/L, which was 129.2% higher than that (1.30g/L) in a PBR with all the nitrogen supplied in batch at initial.	Nitrogen	231-239	translocator protein	Homo sapiens	78-81
27187567-4	2016	In addition, the feeding rates of nitrogen and phosphorus were optimized in the AEM-PBR to maximize biomass production.	Nitrogen	34-42	translocator protein	Homo sapiens	84-87
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	syntaxin 4	Homo sapiens	307-317
27215753-6	2016	Quantitative real-time polymerase chain reaction revealed that the expressions of the following genes related to glucose uptake were elevated: glucose transporter 4 (GLUT4), insulin-responsive aminopeptidase, and vesicle-associated membrane protein 2 for abundant proteins of GLUT4 storage vesicles (GSVs); syntaxin 4 and soluble N-ethylmaleimide-sensitive factor attachment protein 23 for trafficking between the plasma membrane and GSVs; and syntaxin 6 and syntaxin 16 for trafficking between GSVs and the trans-Golgi network.	Nitrogen	330-331	syntaxin 6	Homo sapiens	444-454
27267546-6	2016	RESULTS: After renal ischemia-reperfusion, Cirp(-/-) mice demonstrated a reduction of blood urea nitrogen and creatinine of 53% and 60%, respectively, compared with wild-type mice.	Nitrogen	97-105	cold inducible RNA binding protein	Mus musculus	43-47
25627085-7	2015	Interaction between TM4SF5 and CD44 was through their extracellular domains with N-glycosylation modifications.	Nitrogen	81-82	CD44 antigen	Mus musculus	31-35
25641578-1	2015	The GATA transcription activator Gln3 in the budding yeast (Saccharomyces cerevisiae) activates transcription of nitrogen catabolite repression (NCR)-sensitive genes.	Nitrogen	113-121	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	33-37
25068730-1	2015	A new series of N-heteroarylsubstituted triazolosulfonamide compounds were synthesized and their inhibitory effects on the activity of purified human carbonic anhydrase (hCA) I and II were evaluated.	Nitrogen	16-17	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	150-183
27427963-1	2016	The cellular network composed of the evolutionarily conserved metabolic pathways of protein N-glycosylation, Wnt/beta-catenin signaling pathway, and E-cadherin-mediated cell-cell adhesion plays pivotal roles in determining the balance between cell proliferation and intercellular adhesion during development and in maintaining homeostasis in differentiated tissues.	Nitrogen	92-93	catenin beta 1	Canis lupus familiaris	113-125
27427963-2	2016	These pathways share a highly conserved regulatory molecule, beta-catenin, which functions as both a structural component of E-cadherin junctions and as a co-transcriptional activator of the Wnt/beta-catenin signaling pathway, whose target is the N-glycosylation-regulating gene, DPAGT1.	Nitrogen	247-248	catenin beta 1	Canis lupus familiaris	61-73
27427963-2	2016	These pathways share a highly conserved regulatory molecule, beta-catenin, which functions as both a structural component of E-cadherin junctions and as a co-transcriptional activator of the Wnt/beta-catenin signaling pathway, whose target is the N-glycosylation-regulating gene, DPAGT1.	Nitrogen	247-248	catenin beta 1	Canis lupus familiaris	195-207
27427963-8	2016	We quantified the importance of protein N-glycosylation and synthesis of the DPAGT1 encoded enzyme, GPT, in determining the abundance of cytoplasmic beta-catenin.	Nitrogen	40-41	catenin beta 1	Canis lupus familiaris	149-161
25641578-2	2015	In cells grown in the presence of preferred nitrogen sources, Gln3 is phosphorylated in a TOR-dependent manner and localizes in the cytoplasm.	Nitrogen	44-52	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	62-66
25641578-3	2015	In cells grown in non-preferred nitrogen medium or treated with rapamycin, Gln3 is dephosphorylated and is transported from the cytoplasm to the nucleus, thereby activating the transcription of NCR-sensitive genes.	Nitrogen	32-40	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	75-79
27394101-0	2016	Spin contamination-free N-electron wave functions in the excitation-based configuration interaction treatment.	Nitrogen	24-25	spindlin 1	Homo sapiens	0-4
26116550-8	2015	As previously reported, HGF treatment promoted rapid improvement of kidney function as evidenced by creatinine (Cre) and blood urea nitrogen (BUN) levels.	Nitrogen	132-140	hepatocyte growth factor	Mus musculus	24-27
25494721-2	2015	In this study, we identified a new allele of ROOT HAIR DEFECTIVE3 (RHD3) showing an anthocyanin overaccumulation phenotype under nitrogen starvation conditions.	Nitrogen	129-137	Root hair defective 3 GTP-binding protein (RHD3)	Arabidopsis thaliana	67-71
25784678-5	2015	Here, we investigated the effect of N-linked variable-region glycosylation for BCR interaction with cognate antigen and with lectins of different origins.	Nitrogen	36-37	BCR activator of RhoGEF and GTPase	Homo sapiens	79-82
27185541-4	2016	The observed phase-I metabolites were formed through N-deethylation, N,N-deethylation, N-hydroxylation, and de-esterification, with CYP2B6 and CYP2C19 being the main enzymes catalyzing their formation.	Nitrogen	53-54	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	143-150
27185541-4	2016	The observed phase-I metabolites were formed through N-deethylation, N,N-deethylation, N-hydroxylation, and de-esterification, with CYP2B6 and CYP2C19 being the main enzymes catalyzing their formation.	Nitrogen	69-70	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	143-150
27185541-4	2016	The observed phase-I metabolites were formed through N-deethylation, N,N-deethylation, N-hydroxylation, and de-esterification, with CYP2B6 and CYP2C19 being the main enzymes catalyzing their formation.	Nitrogen	69-70	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	143-150
27185541-4	2016	The observed phase-I metabolites were formed through N-deethylation, N,N-deethylation, N-hydroxylation, and de-esterification, with CYP2B6 and CYP2C19 being the main enzymes catalyzing their formation.	Nitrogen	69-70	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	143-150
25795416-0	2015	Both the autophagy and proteasomal pathways facilitate the Ubp3p-dependent depletion of a subset of translation and RNA turnover factors during nitrogen starvation in Saccharomyces cerevisiae.	Nitrogen	144-152	mRNA-binding ubiquitin-specific protease UBP3	Saccharomyces cerevisiae S288C	59-64
25795416-2	2015	Previous studies have shown that ribosome abundance is reduced during nitrogen starvation by a selective autophagy mechanism termed ribophagy, which is dependent upon the deubiquitinase Ubp3p.	Nitrogen	70-78	mRNA-binding ubiquitin-specific protease UBP3	Saccharomyces cerevisiae S288C	186-191
25795416-10	2015	Together, our results suggest that the autophagy and proteasomal pathways degrade distinct translation and RNA turnover factors in a Ubp3p-dependent manner during nitrogen starvation.	Nitrogen	163-171	mRNA-binding ubiquitin-specific protease UBP3	Saccharomyces cerevisiae S288C	133-138
25909858-9	2015	Complementation of the yeast npr1Delta mutant with each of the three F. fujikuroi NPR1 homologues, resulted in partial restoration of ammonium, arginine and proline uptake by FfNPR1-1 while none of the three kinases affect growth on different nitrogen sources and nitrogen-dependent sorting of FfGap1 in F. fujikuroi.	Nitrogen	243-251	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	82-86
25909858-9	2015	Complementation of the yeast npr1Delta mutant with each of the three F. fujikuroi NPR1 homologues, resulted in partial restoration of ammonium, arginine and proline uptake by FfNPR1-1 while none of the three kinases affect growth on different nitrogen sources and nitrogen-dependent sorting of FfGap1 in F. fujikuroi.	Nitrogen	264-272	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	82-86
25494721-8	2015	The expression of nitrogen starvation-induced anthocyanin biosynthesis genes was negatively regulated by RHD3, but ethylene response genes were positively regulated by RHD3.	Nitrogen	18-26	Root hair defective 3 GTP-binding protein (RHD3)	Arabidopsis thaliana	105-109
25954275-3	2015	This diversity in biological activity is conferred by both a variety of distinct CD44 isoforms generated through complex alternative splicing, posttranslational modifications (e.g., N- and O-glycosylation), interactions with a number of different ligands, and the abundance and spatial distribution of CD44 on the cell surface.	Nitrogen	182-183	CD44 molecule (Indian blood group)	Homo sapiens	81-85
25494721-8	2015	The expression of nitrogen starvation-induced anthocyanin biosynthesis genes was negatively regulated by RHD3, but ethylene response genes were positively regulated by RHD3.	Nitrogen	18-26	Root hair defective 3 GTP-binding protein (RHD3)	Arabidopsis thaliana	168-172
25494721-11	2015	This study uncovered a new physiological function of RHD3 in nitrogen starvation-induced anthocyanin accumulation and ethylene homeostasis.	Nitrogen	61-69	Root hair defective 3 GTP-binding protein (RHD3)	Arabidopsis thaliana	53-57
25725335-7	2015	N2 increased cell viability, ameliorated neuron cell injury by decreasing LDH activity, and inhibited cell apoptotic rate while suppressed apoptotic signaling via inhibiting the bax expression, and elevating the bcl-2 expression.	Nitrogen	0-2	BCL2 associated X, apoptosis regulator	Rattus norvegicus	178-181
25697061-3	2015	Exposure to cold-restraint stress for 3h or subcutaneous infusion of N/OFQ, 1 mug/kg/h for 4h, induced a significant increase of the area of synaptophysin-immunoreactive nerve fibers in the fundic mucosa, while prolonged subcutaneous infusion of N/OFQ, 1 mug/kg/h for 52 h and for 14 days, did not modify the synaptophysin-immunostained fibers.	Nitrogen	69-70	synaptophysin	Rattus norvegicus	141-154
25697061-3	2015	Exposure to cold-restraint stress for 3h or subcutaneous infusion of N/OFQ, 1 mug/kg/h for 4h, induced a significant increase of the area of synaptophysin-immunoreactive nerve fibers in the fundic mucosa, while prolonged subcutaneous infusion of N/OFQ, 1 mug/kg/h for 52 h and for 14 days, did not modify the synaptophysin-immunostained fibers.	Nitrogen	69-70	synaptophysin	Rattus norvegicus	309-322
25697061-3	2015	Exposure to cold-restraint stress for 3h or subcutaneous infusion of N/OFQ, 1 mug/kg/h for 4h, induced a significant increase of the area of synaptophysin-immunoreactive nerve fibers in the fundic mucosa, while prolonged subcutaneous infusion of N/OFQ, 1 mug/kg/h for 52 h and for 14 days, did not modify the synaptophysin-immunostained fibers.	Nitrogen	246-247	synaptophysin	Rattus norvegicus	141-154
25697226-3	2015	This complex mimics the putative Cu(II)(O2( -)) active species of the copper monooxygenase PHM and exhibits enhanced reactivity toward both O-H and C-H substrates in comparison to close analogues [(L)Cu(II)(O2( -))](+), where L contains only nitrogen donor atoms.	Nitrogen	242-250	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	91-94
26099734-4	2015	Even though all zeolites show preferential adsorption of sulfur hexafluoride, we identified local structural features that reduce the affinity for sulfur hexafluoride in zeolites such as MOR and EON, providing exclusive adsorption sites for nitrogen.	Nitrogen	241-249	opioid receptor mu 1	Homo sapiens	187-190
28959282-6	2015	MPG peptide/ DNA complexes were prepared at different N/P (nitrogen/phosphate) ratios and physicochemical characterization and stability of nanoparticles were investigated.	Nitrogen	59-67	N-methylpurine DNA glycosylase	Homo sapiens	0-3
25597816-1	2015	A new tridentate N-donor ligand and its corresponding copper(i) complex have been synthesized to investigate the tyrosinase-like aromatic hydroxylation of an attached phenol.	Nitrogen	17-18	tyrosinase	Homo sapiens	113-123
25864421-2	2015	The development of a robust and versatile Rh(ii)/Zr(iv)-BINOL co-catalytic system not only gives high diastereo- and enantioselective controls of the three-component reaction, but also shows excellent functionality tolerances that allow a wide range of functionalities to be pre-installed in each component and readily undergo one-pot subsequent cyclization reactions, thus providing rapid and diversity-oriented synthesis (DOS) of different types of chiral nitrogen- and/or oxygen-containing polyfunctional heterocycles.	Nitrogen	458-466	Rh blood group D antigen	Homo sapiens	42-48
25389134-0	2015	Genetic ablation of N-linked glycosylation reveals two key folding pathways for R345W fibulin-3, a secreted protein associated with retinal degeneration.	Nitrogen	20-21	EGF containing fibulin extracellular matrix protein 1	Homo sapiens	86-95
25819320-7	2015	From the MEP plot, the negative charge covers the nitro group and the positive region is over the hydroxyl group and N-H part of the imidazole ring.	Nitrogen	117-118	neurolysin	Homo sapiens	9-12
25389134-7	2015	Genetic elimination of F3 N-glycosylation (via an N249Q mutation) caused R345W F3 to aggregate intracellularly and adopt an altered secreted conformation.	Nitrogen	26-27	EGF containing fibulin extracellular matrix protein 1	Homo sapiens	23-25
25389134-7	2015	Genetic elimination of F3 N-glycosylation (via an N249Q mutation) caused R345W F3 to aggregate intracellularly and adopt an altered secreted conformation.	Nitrogen	26-27	EGF containing fibulin extracellular matrix protein 1	Homo sapiens	79-81
25389134-11	2015	These observations suggest that R345W F3, but not WT F3, requires N-glycosylation to acquire a stable, native-like structure.	Nitrogen	66-67	EGF containing fibulin extracellular matrix protein 1	Homo sapiens	38-40
25403919-14	2015	Supplementation with long-chain n-3 PUFA lowered non-fasting triacylglycerol levels, suggestive of a reduction in cardiovascular risk.	Nitrogen	8-9	pumilio RNA binding family member 3	Homo sapiens	36-40
25614217-2	2015	Previously, we have shown that cholera toxin B subunit (CTB), an oral cholera vaccine antigen, is N-glycosylated upon expression in transgenic Nicotiana benthamiana.	Nitrogen	98-99	phosphate cytidylyltransferase 1, choline, beta isoform	Mus musculus	56-59
25614217-4	2015	However, the re-introduction of N-glycosylation to its original or an alternative site significantly relieved the necrosis and provided a high CTB yield without ER retention.	Nitrogen	32-33	phosphate cytidylyltransferase 1, choline, beta isoform	Mus musculus	143-146
25614217-5	2015	Quantitative gene expression analysis of PDI, BiP, bZIP60, SKP1, 26Salpha proteasome and PR1a, and the detection of ubiquitinated CTB polypeptides revealed that N-glycosylation significantly relieved ER stress and hypersensitive response, and facilitated the folding/assembly of CTB.	Nitrogen	161-162	phosphate cytidylyltransferase 1, choline, beta isoform	Mus musculus	130-133
25614217-5	2015	Quantitative gene expression analysis of PDI, BiP, bZIP60, SKP1, 26Salpha proteasome and PR1a, and the detection of ubiquitinated CTB polypeptides revealed that N-glycosylation significantly relieved ER stress and hypersensitive response, and facilitated the folding/assembly of CTB.	Nitrogen	161-162	phosphate cytidylyltransferase 1, choline, beta isoform	Mus musculus	279-282
25487811-5	2015	Our results demonstrate that at low micromolar extracellular concentration N-myristoylated ARCs are capable of reducing the activity of transcription factor CREB through inhibition of PKA.	Nitrogen	75-76	cAMP responsive element binding protein 1	Homo sapiens	157-161
26022737-5	2015	Among single nucleotide polymorphisms (SNPs) of KLKs families, the rs61752561 in KLK3 genes is an unusual missense mutation resulting in the conversion of D102 to N in PSA amino acid sequence.	Nitrogen	40-41	kallikrein related peptidase 3	Homo sapiens	48-52
25392222-1	2015	We have previously shown that ablation of the three N-linked glycosylation sites in the West Nile virus NS1 protein completely attenuates mouse neuroinvasiveness (&gt;=1,000,000 PFU).	Nitrogen	52-53	influenza virus NS1A binding protein	Homo sapiens	104-107
26022737-5	2015	Among single nucleotide polymorphisms (SNPs) of KLKs families, the rs61752561 in KLK3 genes is an unusual missense mutation resulting in the conversion of D102 to N in PSA amino acid sequence.	Nitrogen	40-41	kallikrein related peptidase 3	Homo sapiens	81-85
26022737-5	2015	Among single nucleotide polymorphisms (SNPs) of KLKs families, the rs61752561 in KLK3 genes is an unusual missense mutation resulting in the conversion of D102 to N in PSA amino acid sequence.	Nitrogen	40-41	kallikrein related peptidase 3	Homo sapiens	168-171
25193420-5	2015	The anodic bacteria in the BES demonstrated abilities to utilize the PAM as the sole carbon and nitrogen source to generate electricity.	Nitrogen	96-104	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	69-72
26172322-3	2015	The ESR results revealed that all compounds reduced the fluidity of liposome"s membrane, and the highest activity was observed for compound 2 with N-methylated C-terminal amide bond (Ac-Phe-NMe2 ).	Nitrogen	147-148	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	190-194
25313402-1	2015	The Saccharomyces cerevisiae Siw14, a tyrosine phosphatase involved in the response to caffeine, participates in regulation of the phosphorylation and intracellular localization of Gln3, a GATA transcriptional activator of nitrogen catabolite repression-sensitive genes.	Nitrogen	223-231	putative tyrosine protein phosphatase SIW14	Saccharomyces cerevisiae S288C	29-34
25593049-11	2015	Periostin was also correlated with worsening renal outcomes including serum creatinine, blood urea nitrogen and estimated glomerular filtration rate (eGFR).	Nitrogen	99-107	periostin	Homo sapiens	0-9
26082223-0	2015	Engineering N-Glycosylation Pathway in Insect Cells: Suppression of beta-N-Acetylglucosaminidase and Expression of beta-1,4-Galactosyltransferase.	Nitrogen	12-13	beta-4-galactosyltransferase 7	Drosophila melanogaster	115-145
26082223-4	2015	In addition, we describe coexpression of beta(1,4)-galactosyltransferase (GalT) as a strategy to improve N-glycosylation pattern and enable recombinant therapeutic proteins to be produced in S2 cells with more complex N-glycans.	Nitrogen	105-106	beta-4-galactosyltransferase 7	Drosophila melanogaster	41-72
26082223-4	2015	In addition, we describe coexpression of beta(1,4)-galactosyltransferase (GalT) as a strategy to improve N-glycosylation pattern and enable recombinant therapeutic proteins to be produced in S2 cells with more complex N-glycans.	Nitrogen	105-106	beta-4-galactosyltransferase 7	Drosophila melanogaster	74-78
26110648-1	2015	The co-evolution of the potential N-glycosylation sites of HIV Clade B gp120 was mapped onto the coevolution network of the protein structure using mean field direct coupling analysis (mfDCA).	Nitrogen	34-35	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	71-76
25406445-4	2015	At3g45040, designated AtDOK1, complemented defects in the growth and N-linked glycosylation of the S. cerevisiae sec59 mutant, suggesting that AtDOK1 encodes a functional DOK.	Nitrogen	69-70	dolichol kinase	Saccharomyces cerevisiae S288C	113-118
25817357-1	2015	The aim of the present study was to determine whether a new cyclic analog of enkephalin, cyclo[N(epsilon),N(beta)-carbonyl-d-Lys(2),Dap(5)] enkephalinamide (cUENK6), a preferential mu-(MORs), and, to a lower extent, a delta-opioid receptor (DORs) agonist in vitro, could reinstate ethanol-induced conditioned place preference (CPP).	Nitrogen	95-96	proenkephalin	Rattus norvegicus	77-87
25515537-0	2014	Npr2 inhibits TORC1 to prevent inappropriate utilization of glutamine for biosynthesis of nitrogen-containing metabolites.	Nitrogen	90-98	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	0-4
25515537-4	2014	We determined that Npr2-deficient yeast had a metabolic state distinct from that of wild-type yeast when grown in minimal media containing ammonium as a nitrogen source and a nonfermentable carbon source (lactate).	Nitrogen	153-161	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	19-23
25515537-5	2014	Unlike wild-type yeast, which accumulated glutamine, Npr2-deficient yeast metabolized glutamine into nitrogen-containing metabolites and maintained a high concentration of S-adenosyl methionine (SAM).	Nitrogen	101-109	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	53-57
25515537-7	2014	These data revealed the metabolic basis by which the Npr2 complex regulates cellular homeostasis and demonstrated a key function for TORC1 in regulating the synthesis and utilization of glutamine as a nitrogen source.	Nitrogen	201-209	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	53-57
25817357-1	2015	The aim of the present study was to determine whether a new cyclic analog of enkephalin, cyclo[N(epsilon),N(beta)-carbonyl-d-Lys(2),Dap(5)] enkephalinamide (cUENK6), a preferential mu-(MORs), and, to a lower extent, a delta-opioid receptor (DORs) agonist in vitro, could reinstate ethanol-induced conditioned place preference (CPP).	Nitrogen	95-96	death-associated protein	Rattus norvegicus	132-135
25257619-1	2014	The interaction of H2 and O2 molecules in the presence of nitrogen-doped graphene decorated with either a palladium or gold atom was investigated by using density functional theory.	Nitrogen	58-66	relaxin 2	Homo sapiens	19-28
26109192-6	2015	N-3 supplementation decreased carotid-femoral PWV in older ( -9 +- 2% Precompared to Post; P &lt; 0.05), but not young adults ( 2 +- 3%).	Nitrogen	0-1	solute carrier family 35 member G1	Homo sapiens	85-89
25479762-1	2014	BACKGROUND: gamma-Glutamyl transpeptidase 1 (GGT1) is an N-glycosylated membrane protein that catabolizes extracellular glutathione and other gamma-glutamyl-containing substrates.	Nitrogen	8-9	gamma-glutamyltransferase 1	Homo sapiens	12-43
25479762-1	2014	BACKGROUND: gamma-Glutamyl transpeptidase 1 (GGT1) is an N-glycosylated membrane protein that catabolizes extracellular glutathione and other gamma-glutamyl-containing substrates.	Nitrogen	8-9	gamma-glutamyltransferase 1	Homo sapiens	45-49
25541571-9	2014	Samples can be promptly deoxygenated or equilibrated with an air/nitrogen mixture inside the resonator, which is significant in saturation-recovery measurements and in spin-label oximetry.	Nitrogen	65-73	spindlin 1	Homo sapiens	168-172
26263333-2	2015	The CoP-coated (2.0 mg cm(-2)) n(+)p-Si MW photocathodes were stable for over 12 h of continuous operation and produced an open-circuit photovoltage (Voc) of 0.48 V, a light-limited photocurrent density (Jph) of 17 mA cm(-2), a fill factor (ff) of 0.24, and an ideal regenerative cell efficiency (etaIRC) of 1.9% under simulated 1 Sun illumination.	Nitrogen	31-32	caspase recruitment domain family member 16	Homo sapiens	4-7
25433991-4	2014	Mechanism studies revealed that Cd(II) affected the transformations of intracellular PHAs and glycogen, and the activities of oxidoreductase and polyphosphate kinase, resulted in the decrease of nitrite oxidizing bacteria and polyphosphate accumulating organisms abundance, which might be the major reason for the negative effects of long-term exposure to 10 mg L(-1) Cd(II) on biological nitrogen and phosphorus removal.	Nitrogen	389-397	thioredoxin reductase 1	Homo sapiens	126-140
25285659-2	2014	The two N atoms in the 2cqn ligand are in trans position in the synthesized cis-1 isomer, while they are in cis position in the cis-2 isomer.	Nitrogen	8-9	suppressor of cytokine signaling 2	Homo sapiens	128-133
27020572-6	2016	Moreover, the simultaneous mutation of these N-glycosylation sites prevents Env incorporation into virions and Env-mediated cell-to-cell fusion.	Nitrogen	45-46	endogenous retrovirus group K member 20	Homo sapiens	76-79
27020572-6	2016	Moreover, the simultaneous mutation of these N-glycosylation sites prevents Env incorporation into virions and Env-mediated cell-to-cell fusion.	Nitrogen	45-46	endogenous retrovirus group K member 20	Homo sapiens	111-114
25966763-3	2015	Here, we show the crucial impact of N-terminal acetylation on the turnover of one plant NLR, Suppressor of NPR1, Constitutive 1 (SNC1), in Arabidopsis thaliana.	Nitrogen	36-37	TIR-NBS-LRR class disease resistance protein	Arabidopsis thaliana	93-127
27017073-5	2016	In terms of water soluble ions, NO3(-)/SO4(2-) in PM1 increased with the aggravation of haze pollution, implying that mobile sources dominated on haze days, so is nitrogen oxidation ratio (NOR).	Nitrogen	163-171	transmembrane protein 11	Homo sapiens	50-53
27374441-9	2016	The DNMT1, DNMT3a and DNMT3b levels in the CCI+NS group were increased significantly compared with that in the sham+NS group on the 14th day after surgery (all P&lt;0.05).	Nitrogen	47-49	DNA methyltransferase 3 beta	Rattus norvegicus	22-28
25238963-7	2014	Moreover, we provide biochemical evidence that this decrease is associated with reduced Wnt8 ligand and elevated Lrp6 coreceptor, which we show are both substrates for N-linked fucosylation in zebrafish embryos.	Nitrogen	168-169	wingless-type MMTV integration site family, member 8a	Danio rerio	88-92
25966763-3	2015	Here, we show the crucial impact of N-terminal acetylation on the turnover of one plant NLR, Suppressor of NPR1, Constitutive 1 (SNC1), in Arabidopsis thaliana.	Nitrogen	36-37	TIR-NBS-LRR class disease resistance protein	Arabidopsis thaliana	129-133
25078904-5	2014	The results revealed that independent of the protein-level change, N-glycosylation modifications of integrin alpha 3 (ITGA3) were inhibited by hypoxia, unlike in other integrin subunits.	Nitrogen	67-68	integrin subunit alpha 3	Homo sapiens	100-116
25078904-5	2014	The results revealed that independent of the protein-level change, N-glycosylation modifications of integrin alpha 3 (ITGA3) were inhibited by hypoxia, unlike in other integrin subunits.	Nitrogen	67-68	integrin subunit alpha 3	Homo sapiens	118-123
27374441-10	2016	The DNMT1, DNMT3a and DNMT3b expressions in the CCI+ 5-AZA group were decreased significantly compared with that in the CCI+NS group (all P&lt;0.05), but they still increased compared with that in the sham+NS group (all P&lt;0.05).	Nitrogen	124-126	DNA methyltransferase 3 beta	Rattus norvegicus	22-28
25752662-4	2015	The crystal structures of SF4  NC5 H5 , SF4  4-NC5 H4 (CH3 ), and SF4  4-NC5 H4 N(CH3 )2 revealed weak S N dative bonds with nitrogen coordinating in the equatorial position of SF4 .	Nitrogen	125-133	SURP and G-patch domain containing 1	Homo sapiens	26-29
27293103-0	2016	Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation.	Nitrogen	68-76	NIN like protein 7	Arabidopsis thaliana	30-34
27293103-0	2016	Overexpression of Arabidopsis NLP7 improves plant growth under both nitrogen-limiting and -sufficient conditions by enhancing nitrogen and carbon assimilation.	Nitrogen	126-134	NIN like protein 7	Arabidopsis thaliana	30-34
27293103-5	2016	Here we report that NLP7 (NIN-LIKE PROTEIN 7) is a potential candidate to improve plant nitrogen use ability.	Nitrogen	88-96	NIN like protein 7	Arabidopsis thaliana	20-24
27293103-5	2016	Here we report that NLP7 (NIN-LIKE PROTEIN 7) is a potential candidate to improve plant nitrogen use ability.	Nitrogen	88-96	NIN like protein 7	Arabidopsis thaliana	26-44
25193512-9	2014	Furthermore, knockout of BRCA2 markedly sensitized DLD-1 cells to the clinical nitrogen mustard prodrugs TH-302 and PR-104 and significantly augmented sterilization of clonogens by these agents in xenografts, both as monotherapy and in combination with radiotherapy, but had less effect on activity of the benzotriazine di-N-oxide SN30000.	Nitrogen	79-87	BRCA2 DNA repair associated	Homo sapiens	25-30
25209573-3	2014	Dissolved gas is transferred through the membrane to a continuous flow of high purity nitrogen, which is then measured by an off-axis integrated cavity output spectrometer (OA-ICOS).	Nitrogen	86-94	inducible T cell costimulator	Homo sapiens	176-180
27293103-6	2016	When overexpressed in Arabidopsis, NLP7 increases plant biomass under both nitrogen-poor and -rich conditions with better-developed root system and reduced shoot/root ratio.	Nitrogen	75-83	NIN like protein 7	Arabidopsis thaliana	35-39
27293103-7	2016	NLP7-overexpressing plants show a significant increase in key nitrogen metabolites, nitrogen uptake, total nitrogen content, and expression levels of genes involved in nitrogen assimilation and signalling.	Nitrogen	62-70	NIN like protein 7	Arabidopsis thaliana	0-4
25752662-4	2015	The crystal structures of SF4  NC5 H5 , SF4  4-NC5 H4 (CH3 ), and SF4  4-NC5 H4 N(CH3 )2 revealed weak S N dative bonds with nitrogen coordinating in the equatorial position of SF4 .	Nitrogen	125-133	SURP and G-patch domain containing 1	Homo sapiens	40-43
27293103-7	2016	NLP7-overexpressing plants show a significant increase in key nitrogen metabolites, nitrogen uptake, total nitrogen content, and expression levels of genes involved in nitrogen assimilation and signalling.	Nitrogen	84-92	NIN like protein 7	Arabidopsis thaliana	0-4
27293103-7	2016	NLP7-overexpressing plants show a significant increase in key nitrogen metabolites, nitrogen uptake, total nitrogen content, and expression levels of genes involved in nitrogen assimilation and signalling.	Nitrogen	84-92	NIN like protein 7	Arabidopsis thaliana	0-4
25085507-2	2014	Previous studies in yeast have shown that three GTPases-Gtr1, Gtr2, and Rho1-bind to TORC1 in nitrogen and amino acid starvation conditions to block phosphorylation of the S6 kinase Sch9 and activate protein phosphatase 2A (PP2A).	Nitrogen	94-102	Gtr2p	Saccharomyces cerevisiae S288C	62-66
24036313-4	2014	X-ray cocrystallographic analysis of the hVDR-1a complex showed new hydrogen bond formation between one of the nitrogen atoms of the tetrazole ring and Arg274.	Nitrogen	111-119	vitamin D receptor	Homo sapiens	41-45
27293103-7	2016	NLP7-overexpressing plants show a significant increase in key nitrogen metabolites, nitrogen uptake, total nitrogen content, and expression levels of genes involved in nitrogen assimilation and signalling.	Nitrogen	84-92	NIN like protein 7	Arabidopsis thaliana	0-4
27293103-8	2016	More importantly, overexpression of NLP7 also enhances photosynthesis rate and carbon assimilation, whereas knockout of NLP7 impaired both nitrogen and carbon assimilation.	Nitrogen	139-147	NIN like protein 7	Arabidopsis thaliana	120-124
27151646-6	2016	Consistent with these results, a dramatic increase in the N-glycosylation of ICAM-1 in BRECs cultured with a high concentration of glucose was observed, which could be partially attenuated by tunicamycin treatment.	Nitrogen	58-59	intercellular adhesion molecule 1	Bos taurus	77-83
27151646-7	2016	CONCLUSION: High glucose-induced upregulation of ICAM-1 on the surface of BRECs could be ascribed to the alterations in its N-glycosylation at least in part, indicating that interference with the glycosylation of ICAM-1 may contribute to improving the efficiency of current therapies with diabetic retinopathy.	Nitrogen	2-3	intercellular adhesion molecule 1	Bos taurus	49-55
26563299-0	2016	Recombinant human heterodimeric IL-15 complex displays extensive and reproducible N- and O-linked glycosylation.	Nitrogen	82-83	interleukin 15	Homo sapiens	32-37
24850152-6	2014	However, mice deficient in Crry on proximal tubular epithelial cells developed exacerbated renal injury when subjected to renal ischemia-reperfusion, showing increased blood urea nitrogen levels, higher tubular injury scores, more tubular epithelial cell apoptosis, and inflammatory infiltrates.	Nitrogen	179-187	complement component (3b/4b) receptor 1-like	Mus musculus	27-31
26563299-7	2016	The two potential IL-15 N-glycosylation sites (Asn71 and Asn112) located at the IL-2 receptor interface were unoccupied.	Nitrogen	24-25	interleukin 15	Homo sapiens	18-23
25752662-4	2015	The crystal structures of SF4  NC5 H5 , SF4  4-NC5 H4 (CH3 ), and SF4  4-NC5 H4 N(CH3 )2 revealed weak S N dative bonds with nitrogen coordinating in the equatorial position of SF4 .	Nitrogen	125-133	SURP and G-patch domain containing 1	Homo sapiens	40-43
26563299-8	2016	Mass analysis of intact IL-15 confirmed its N-glycosylation and suggested that Asn79-glycosylation partially prevents Asn77-deamidation.	Nitrogen	44-45	interleukin 15	Homo sapiens	24-29
25752662-4	2015	The crystal structures of SF4  NC5 H5 , SF4  4-NC5 H4 (CH3 ), and SF4  4-NC5 H4 N(CH3 )2 revealed weak S N dative bonds with nitrogen coordinating in the equatorial position of SF4 .	Nitrogen	125-133	SURP and G-patch domain containing 1	Homo sapiens	40-43
25106820-6	2014	We conclude that, although inhibition of NRT1.1-mediated NO3 (-) uptake by cadmium might have negative effects on nitrogen nutrition in plants, it has a positive effect on cadmium detoxification by reducing cadmium entry into roots.	Nitrogen	114-122	nitrate transporter 1.1	Arabidopsis thaliana	41-45
25897204-10	2015	Recombinant N-acetylgalactosamine-6-sulfate sulfatase (GALNS) in Escherichia coli BL21 (DE3) (erGALNS) and in the methylotrophic yeast Pichia pastoris (prGALNS) has been produced as an alternative to the conventional production in Chinese hamster ovary cells.	Nitrogen	12-13	galactosamine (N-acetyl)-6-sulfatase	Homo sapiens	55-60
25184363-3	2014	The multiplicity of NQR lines indicates the presence of a stable beta form of anhydrous caffeine at 233 K and stable form II of anhydrous theobromine at 213 K. The assignment of signals detected in NQR experiment to particular nitrogen atoms was made on the basis of quantum chemistry calculations performed for monomer, cluster, and solid at the DFT/GGA/BLYP/DPD level.	Nitrogen	227-235	dihydropyrimidine dehydrogenase	Homo sapiens	360-363
27252251-0	2016	Effect of dietary n-3 PUFA supplementation on the muscle transcriptome in older adults.	Nitrogen	18-19	pumilio RNA binding family member 3	Homo sapiens	22-26
26992523-0	2016	Fluorescent probes for "off-on" highly sensitive detection of Hg2+ and L-cysteine based on nitrogen-doped carbon dots.	Nitrogen	91-99	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	62-65
25601990-0	2015	N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.	Nitrogen	0-1	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	38-44
25217917-3	2014	We employed ultraviolet absorption to probe simultaneously CH2I2, CH2OO, CH2I, and IO in the reaction system of CH2I + O2 upon photolysis at 248 nm of a flowing mixture of CH2I2, O2, and N2 (or SF6) in the pressure range 7.6-779 Torr to investigate the reaction kinetics.	Nitrogen	187-189	EBP cholestenol delta-isomerase	Homo sapiens	112-121
25217917-6	2014	We derived a rate coefficient also for the self-reaction of CH2OO as k = (8 +- 4) x 10(-11) cm(3) molecule(-1) s(-1) at 295 K. The yield of CH2OO from CH2I + O2 was found to have a pressure dependence on N2 and O2 smaller than in previous reports; for air under 1 atm, the yield of ~30% is about twice of previous estimates.	Nitrogen	204-206	EBP cholestenol delta-isomerase	Homo sapiens	151-160
27074728-3	2016	The transition to the high-spin state is accompanied by an increase in Fe-N bond lengths and a concomitant contraction of intraligand N-N bonds.	Nitrogen	74-75	spindlin 1	Homo sapiens	27-31
25601990-3	2015	A traditional model of ABP tumorigenesis involves initial CYP1A2-mediated N-hydroxylation, which eventually leads to production of mutagenic ABP-DNA adducts that initiate tumor growth.	Nitrogen	74-75	cytochrome P450, family 1, subfamily a, polypeptide 2	Mus musculus	58-64
27074728-3	2016	The transition to the high-spin state is accompanied by an increase in Fe-N bond lengths and a concomitant contraction of intraligand N-N bonds.	Nitrogen	134-135	spindlin 1	Homo sapiens	27-31
25202057-7	2014	This finding was reflected in the higher ratio n-6-PUFA/n-3-PUFA observed in cancer patients.	Nitrogen	7-8	pumilio RNA binding family member 3	Homo sapiens	51-55
25601990-7	2015	Isozyme-selective inhibition experiments using liver microsomes from wild-type and genetically modified mice identified CYP2E1 as a major ABP N-hydroxylating enzyme.	Nitrogen	142-143	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	120-126
25202057-7	2014	This finding was reflected in the higher ratio n-6-PUFA/n-3-PUFA observed in cancer patients.	Nitrogen	7-8	pumilio RNA binding family member 3	Homo sapiens	60-64
25601990-8	2015	The N-hydroxylation of ABP by transiently expressed CYP2E1 produced oxidative stress in cultured mouse hepatoma cells.	Nitrogen	4-5	cytochrome P450, family 2, subfamily e, polypeptide 1	Mus musculus	52-58
25689493-5	2015	The inhibitory efficacy of N-myristoylated Cblin on IRS-1 ubiquitination in C2C12 myotubes was approximately fourfold larger than that of Cblin.	Nitrogen	27-28	insulin receptor substrate 1	Mus musculus	52-57
25109237-0	2014	N-myristoylation regulates the axonal distribution of the Fragile X-related protein FXR2P.	Nitrogen	0-1	FMR1 autosomal homolog 2	Homo sapiens	84-89
26979064-6	2016	The fluorescence was detected in the cytosol when the 25-residue N-terminal sequence was deleted from PCaP1 indicating essential contribution of N-myristoylation to the plasma membrane anchoring.	Nitrogen	65-66	plasma-membrane associated cation-binding protein 1	Arabidopsis thaliana	102-107
25689493-7	2015	Finally, we demonstrated that N-myristoylated Cblin prevented the wet weight loss, IRS-1 degradation, and MAFbx/atrogin-1 and MuRF-1 expression in gastrocnemius muscle of DEX-treated mice approximately fourfold more effectively than Cblin.	Nitrogen	30-31	insulin receptor substrate 1	Mus musculus	83-88
27042863-4	2016	The change in spin state coincides with a significant change in the degree of pi-bonding between Fe and the bound N atom of the phosphiniminato ligand.	Nitrogen	114-115	spindlin 1	Homo sapiens	14-18
26949128-5	2016	The interaction resulting from the change in binding configuration also affects the position of the HOMO level, where a shift of +0.2 eV is observed when heated to 200  C. For K77, parts of the thiocyanate units are detached and the nitrogen atom leaves the electrode whereas sulfur remains on the surface in various forms of sulfurous oxides.	Nitrogen	233-241	keratin 77	Homo sapiens	176-179
24510007-11	2014	The serum IL-21 level was positively correlated with blood urea nitrogen (BUN) and creatinine (Cr), suggesting that the serum IL-21 level is associated with the disease severity of HFRS.	Nitrogen	64-72	interleukin 21	Homo sapiens	10-15
24510007-11	2014	The serum IL-21 level was positively correlated with blood urea nitrogen (BUN) and creatinine (Cr), suggesting that the serum IL-21 level is associated with the disease severity of HFRS.	Nitrogen	64-72	interleukin 21	Homo sapiens	126-131
25014126-4	2014	The predominant cis-conformer in [C2C1C1(4)pi][NTf2] at its liquid state is observed under ambient conditions, where the ethyl group locates at the equatorial position of quaternary nitrogen atom, consistent with the calculated results.	Nitrogen	182-190	nuclear transport factor 2	Homo sapiens	47-51
26958078-6	2016	The std1 mutant accumulates higher levels of starch and oil than wild-type and maintains a higher photosynthetic activity under nitrogen starvation.	Nitrogen	128-136	uncharacterized protein	Chlamydomonas reinhardtii	4-8
25689493-7	2015	Finally, we demonstrated that N-myristoylated Cblin prevented the wet weight loss, IRS-1 degradation, and MAFbx/atrogin-1 and MuRF-1 expression in gastrocnemius muscle of DEX-treated mice approximately fourfold more effectively than Cblin.	Nitrogen	30-31	F-box protein 32	Mus musculus	106-111
24968285-4	2014	The effect of N-tert-butyl substitution on the charge density and electron density localization of the nitronyl carbon as well as on the free energies of nitrone reactivity with O2( -) and HO2( ) were computationally rationalized at the PCM/B3LYP/6-31+G**//B3LYP/6-31G* level of theory.	Nitrogen	14-15	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	243-246
25689493-7	2015	Finally, we demonstrated that N-myristoylated Cblin prevented the wet weight loss, IRS-1 degradation, and MAFbx/atrogin-1 and MuRF-1 expression in gastrocnemius muscle of DEX-treated mice approximately fourfold more effectively than Cblin.	Nitrogen	30-31	F-box protein 32	Mus musculus	112-121
24884609-6	2014	Next, we performed glycosidase-assisted LC-MS/MS analysis of ITIH4 trypsin-GluC glycopeptides enriched via hydrophilic interaction liquid chromatography to characterize ITIH4 N-glycoforms.	Nitrogen	0-1	glucosylceramidase beta 3 (gene/pseudogene)	Homo sapiens	75-79
25889420-8	2015	The typical consensus glycosylation sequence of Asn-X-Ser/Thr was identified in MdPGIP1, indicating potential N-linked glycosylation of MdPGIP1.	Nitrogen	110-111	polygalacturonase inhibitor-like	Malus domestica	80-87
24814332-0	2014	Carbon and nitrogen isotope ratios of factory-produced RDX and HMX.	Nitrogen	11-19	radixin	Homo sapiens	55-58
26699903-1	2016	SCUBE1 (S1), a secreted and membrane-bound glycoprotein, has a modular protein structure composed of an N-terminal signal peptide sequence followed by nine epidermal growth factor (EGF)-like repeats, a spacer region and three cysteine-rich (CR) motifs with multiple potential N-linked glycosylation sites, and one CUB domain at the C-terminus.	Nitrogen	104-105	signal peptide, CUB domain, EGF-like 1	Danio rerio	0-6
26742847-3	2016	CaValpha2delta1 is potentially the most heavily N-glycosylated subunit in the cardiac L-type CaV1.2 channel complex.	Nitrogen	48-49	calcium voltage-gated channel subunit alpha1 C	Homo sapiens	93-99
24814332-5	2014	RDX (15)N depletion relative to the nitrogen-containing substrates (-3.6%) was smaller in the Bachmann process than in the direct nitration process (-12.6% to -10.6%).	Nitrogen	36-44	radixin	Homo sapiens	0-3
25889420-8	2015	The typical consensus glycosylation sequence of Asn-X-Ser/Thr was identified in MdPGIP1, indicating potential N-linked glycosylation of MdPGIP1.	Nitrogen	110-111	polygalacturonase inhibitor-like	Malus domestica	136-143
25568315-1	2015	The extracellular loop 3 (EL-3) of SLC4 Na(+)-coupled transporters contains 4 highly conserved cysteines and multiple N-glycosylation consensus sites.	Nitrogen	40-41	spectrin beta, erythrocytic	Homo sapiens	4-30
25079999-8	2014	The efficiency of Hg removal in the N2-H2S-H2-CO-Hg atmosphere (simulated coal gas) was higher than that in N2-H2S-Hg and N2-Hg atmospheres, which showed that H2 and CO, with their reducing capacity, could benefit promote the removal of Hg.	Nitrogen	36-38	relaxin 2	Homo sapiens	159-168
26776360-0	2016	Design and discovery of new pyrimidine coupled nitrogen aromatic rings as chelating groups of JMJD3 inhibitors.	Nitrogen	47-55	KDM1 lysine (K)-specific demethylase 6B	Mus musculus	94-99
25889839-8	2015	Gain- and loss-of-function studies indicated that secretory ITLN1 facilitated the NDRG2 expression, resulting in down-regulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 9 (MMP-9), in NB cell lines SH-SY5Y, SK-N-BE(2), and SK-N-SH.	Nitrogen	63-64	NDRG family member 2	Homo sapiens	82-87
26744214-7	2016	A nitrogen compound transport cluster containing some members of the NRT/PTR family was regulated by both NRG2 and NRT1.1, while no nitrogen-related clusters showed regulation by both NRG2 and NLP7.	Nitrogen	2-10	nitrate transporter 1.1	Arabidopsis thaliana	115-121
26657319-1	2016	Transition metal-nitrogen/carbon (M-N/C, M = Fe, Co) catalysts are synthesized using environmentally friendly histidine-tag-rich elastin protein beads, metal sulfate and water soluble carbon nanotubes followed by post-annealing and acid leaching processes.	Nitrogen	17-25	elastin	Homo sapiens	129-136
24725364-3	2014	We have previously reported that Epac1, an exchange protein activated by cAMP, increases N-sulfation of HS in melanoma.	Nitrogen	89-90	Rap guanine nucleotide exchange factor 3	Homo sapiens	33-38
24725364-8	2014	Furthermore, knockdown of Epac1 reduced N-sulfation of HS chains attached to perlecan, a major secreted type of HS proteoglycan that mediates the binding of FGF2 to FGF receptor.	Nitrogen	40-41	Rap guanine nucleotide exchange factor 3	Homo sapiens	26-31
25639242-7	2015	However, we find that a second homolog CaMKK(Ppk34) is specifically required to stimulate AMPKalpha(Ssp2) activation in response to nitrogen stress.	Nitrogen	132-140	calcium/calmodulin dependent protein kinase kinase 2	Homo sapiens	39-44
24798337-2	2014	KDM6A (UTX) and KDM6B (JMJD3) are KDM6 subfamily members that catalyze demethylation of N(epsilon)-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression.	Nitrogen	88-89	lysine demethylase 6B	Homo sapiens	16-21
24798337-2	2014	KDM6A (UTX) and KDM6B (JMJD3) are KDM6 subfamily members that catalyze demethylation of N(epsilon)-methylated histone 3 lysine 27 (H3K27), a mark important for transcriptional repression.	Nitrogen	88-89	lysine demethylase 6B	Homo sapiens	23-28
26578259-7	2016	Moreover, 3-D/Ni-Fe hierarchical nanosheet arrays showed higher sensitivity (7.90 muA muM(-1) cm(-2)) with wide linear glucose concentration ranging from 0.05 muM to 0.2 mM, and the low detection limit (LOD) of 0.031 muM (S/N = 3) is achieved by the amperometry method.	Nitrogen	14-15	PWWP domain containing 3A, DNA repair factor	Homo sapiens	86-92
25596127-4	2015	In this study we observed that bZIP transcription factor AtTGA4 (TGACG motif-binding factor 4) was induced by both drought and low nitrogen stresses, and that overexpression of AtTGA4 simultaneously improved drought resistance and reduced nitrogen starvation in Arabidopsis.	Nitrogen	131-139	TGACG motif-binding factor 4	Arabidopsis thaliana	57-63
26375942-8	2016	CYP2C19 genotyping was performed because it influences N-demethylation of citalopram to desmethylcitalopram.	Nitrogen	55-56	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	0-7
27161009-1	2016	An overview of anticancer active (arene)ruthenium(II) complexes coordinated to period 2 element-based ligand systems, i.e., carbon-, nitrogen-, and oxygen-coordinated ligands, is provided in this mini-review.	Nitrogen	133-141	period circadian regulator 2	Homo sapiens	79-87
26645909-7	2016	Experiments with transgenic Arabidopsis lines indicate a role of maize glucosyltransferase BX9 in BOA-N-glycosylation.	Nitrogen	102-103	DIMBOA UDP-glucosyltransferase BX9	Zea mays	91-94
24909770-1	2014	A nitrogen-doped graphene/carbon nanotubes (NGR-NCNTs) nanocomposite was employed into the study of the electrochemical sensor via electrodeposition for the first time.	Nitrogen	2-10	reticulon 4 receptor	Homo sapiens	44-47
24828975-8	2014	The N-demethylation was catalyzed by CYP2B6, CYP2C19, CYP2D6, and CYP3A4, the aromatic hydroxylation by CYP2C19 and CYP2D6, and the aliphatic hydroxylation was catalyzed by CYP1A2, CYP2B6, CYP2C19, and CYP3A4.	Nitrogen	4-5	cytochrome P450, family 2, subfamily d, polypeptide 4	Rattus norvegicus	116-122
24828975-8	2014	The N-demethylation was catalyzed by CYP2B6, CYP2C19, CYP2D6, and CYP3A4, the aromatic hydroxylation by CYP2C19 and CYP2D6, and the aliphatic hydroxylation was catalyzed by CYP1A2, CYP2B6, CYP2C19, and CYP3A4.	Nitrogen	4-5	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	173-179
24519758-0	2014	Characterization of goat milk lactoferrin N-glycans and comparison with the N-glycomes of human and bovine milk.	Nitrogen	42-43	lactotransferrin	Capra hircus	30-41
25596127-4	2015	In this study we observed that bZIP transcription factor AtTGA4 (TGACG motif-binding factor 4) was induced by both drought and low nitrogen stresses, and that overexpression of AtTGA4 simultaneously improved drought resistance and reduced nitrogen starvation in Arabidopsis.	Nitrogen	131-139	TGACG motif-binding factor 4	Arabidopsis thaliana	65-93
25596127-4	2015	In this study we observed that bZIP transcription factor AtTGA4 (TGACG motif-binding factor 4) was induced by both drought and low nitrogen stresses, and that overexpression of AtTGA4 simultaneously improved drought resistance and reduced nitrogen starvation in Arabidopsis.	Nitrogen	131-139	TGACG motif-binding factor 4	Arabidopsis thaliana	177-183
24728193-6	2014	Although ARO8 is also present in S. cerevisiae and is induced by extracellular histidine, the yeast cannot use histidine as its sole nitrogen source, possibly due to growth inhibition by a downstream degradation product.	Nitrogen	133-141	bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	9-13
25596127-4	2015	In this study we observed that bZIP transcription factor AtTGA4 (TGACG motif-binding factor 4) was induced by both drought and low nitrogen stresses, and that overexpression of AtTGA4 simultaneously improved drought resistance and reduced nitrogen starvation in Arabidopsis.	Nitrogen	239-247	TGACG motif-binding factor 4	Arabidopsis thaliana	57-63
25596127-4	2015	In this study we observed that bZIP transcription factor AtTGA4 (TGACG motif-binding factor 4) was induced by both drought and low nitrogen stresses, and that overexpression of AtTGA4 simultaneously improved drought resistance and reduced nitrogen starvation in Arabidopsis.	Nitrogen	239-247	TGACG motif-binding factor 4	Arabidopsis thaliana	65-93
26701912-1	2015	Synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins couple their stage-wise folding/assembly to rapid exocytosis of neurotransmitters in a Munc18-1-dependent manner.	Nitrogen	17-18	syntaxin binding protein 1	Homo sapiens	175-183
25596127-4	2015	In this study we observed that bZIP transcription factor AtTGA4 (TGACG motif-binding factor 4) was induced by both drought and low nitrogen stresses, and that overexpression of AtTGA4 simultaneously improved drought resistance and reduced nitrogen starvation in Arabidopsis.	Nitrogen	239-247	TGACG motif-binding factor 4	Arabidopsis thaliana	177-183
25596127-5	2015	Following drought stress there were higher nitrogen and proline contents in transgenic AtTGA4 plants than in wild type controls, and activity of the key enzyme nitrite reductase (NIR) involved in nitrate assimilation processes was also higher.	Nitrogen	43-51	TGACG motif-binding factor 4	Arabidopsis thaliana	87-93
26497208-5	2015	We demonstrated that glycosylation of CDCP1 is a prerequisite for protein stability and plasma membrane localization, and that the expression level and extent of N-glycosylation of CDCP1 correlated with metastatic status.	Nitrogen	162-163	CUB domain containing protein 1	Homo sapiens	181-186
24467264-8	2014	Administration of kallistatin attenuated renal damage and decreased blood urea nitrogen and serum creatinine levels, but increased endothelial nitric oxide synthase and nitric oxide levels in the kidney.	Nitrogen	79-87	serpin family A member 4	Homo sapiens	18-29
25596127-7	2015	Thus genetic transformation with AtTGA4 may provide a new approach to simultaneously improve crop tolerance to drought and low nitrogen stresses.	Nitrogen	127-135	TGACG motif-binding factor 4	Arabidopsis thaliana	33-39
25046564-5	2015	The loop-close form is relatively tight in space, which squeezes water molecules out of the interface of alpha-helix and beta2 strand, joined by the connecting loop region; accordingly, the water-scant environment leads to the sole existence of the N(1)-H isomer emission.	Nitrogen	249-250	neuronal differentiation 1	Homo sapiens	121-126
24585881-1	2014	When the sta6 (starch-null) strain of the green microalga Chlamydomonas reinhardtii is nitrogen starved in acetate and then "boosted" after 2 days with additional acetate, the cells become "obese" after 8 days, with triacylglyceride (TAG)-filled lipid bodies filling their cytoplasm and chloroplasts.	Nitrogen	87-95	uncharacterized protein	Chlamydomonas reinhardtii	9-13
26565558-7	2015	For the Cu(II)-H1A/H9A and Cu(II)-H1A/H12A systems, the Cu3H-9L complexes are likely formed by the coordination of amide nitrogen atoms towards C-termini with ring sizes (7,5,5).	Nitrogen	121-129	H1.1 linker histone, cluster member	Homo sapiens	15-18
26565558-7	2015	For the Cu(II)-H1A/H9A and Cu(II)-H1A/H12A systems, the Cu3H-9L complexes are likely formed by the coordination of amide nitrogen atoms towards C-termini with ring sizes (7,5,5).	Nitrogen	121-129	H1.1 linker histone, cluster member	Homo sapiens	34-37
26681516-2	2015	Studies in yeast and human cells have shown that nitrogen/amino acid starvation signals act through Npr2/Npr3 and the small GTPases Gtr1/Gtr2 (Rags in humans) to inhibit TORC1.	Nitrogen	49-57	ephrin A5	Homo sapiens	143-147
24089324-11	2014	CONCLUSION: The reactive oxygen/nitrogen species-PARP pathway plays a pathogenetic role in the development of liver inflammation, metabolism, and fibrosis.	Nitrogen	32-40	poly (ADP-ribose) polymerase family, member 1	Mus musculus	49-53
25490879-3	2015	In the process, the indole unit of L1 is deprotonated by the metal alkyl species and the imino C=N group is transferred to the amido group by alkyl CH2 SiMe3 insertion, affording a new dianionic ligand that bridges two metal alkyl units in mu-eta(2) :eta(1) :eta(1) bonding modes, forming the dinuclear rare-earth metal alkyl complexes.	Nitrogen	97-98	secreted phosphoprotein 1	Homo sapiens	251-257
24287290-1	2014	Recent work has shown that a DBF4 analog in yeast may be a target of nitrogen-containing bisphosphonates.	Nitrogen	69-77	protein serine/threonine kinase activating protein DBF4	Saccharomyces cerevisiae S288C	29-33
26715854-12	2015	CONCLUSION: The status of NAT2 slow N-acetylation is associated with bladder cancer risks, and may increase the risk of bladder cancer.	Nitrogen	2-3	N-acetyltransferase 2	Homo sapiens	26-30
26256061-6	2015	Furthermore, the yh-meprin beta was N-glycosylated and secreted as a dimer with a molecular mass of 148 kDa.	Nitrogen	36-37	meprin A subunit beta	Homo sapiens	20-31
24631364-2	2014	The combined MD simulations and QM/MM-PBSA calculations reveal that the most important structural parameters affecting the CYP2A6-inhibitor binding affinity are two crucial internuclear distances, that is, the distance between the heme iron atom of CYP2A6 and the coordinating atom of the inhibitor, and the hydrogen-bonding distance between the N297 side chain of CYP2A6 and the pyridine nitrogen of the inhibitor.	Nitrogen	389-397	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	123-129
24631364-2	2014	The combined MD simulations and QM/MM-PBSA calculations reveal that the most important structural parameters affecting the CYP2A6-inhibitor binding affinity are two crucial internuclear distances, that is, the distance between the heme iron atom of CYP2A6 and the coordinating atom of the inhibitor, and the hydrogen-bonding distance between the N297 side chain of CYP2A6 and the pyridine nitrogen of the inhibitor.	Nitrogen	389-397	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	249-255
24631364-2	2014	The combined MD simulations and QM/MM-PBSA calculations reveal that the most important structural parameters affecting the CYP2A6-inhibitor binding affinity are two crucial internuclear distances, that is, the distance between the heme iron atom of CYP2A6 and the coordinating atom of the inhibitor, and the hydrogen-bonding distance between the N297 side chain of CYP2A6 and the pyridine nitrogen of the inhibitor.	Nitrogen	389-397	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	249-255
26505865-4	2015	After characterization by electron microscopy, X-ray diffraction, nitrogen sorption, fourier transform infrared spectroscopy and vibrating sample magnetometry, the as-prepared mZIF-8@GOx was confirmed with the robust core-shell structure, the monodisperse nanoparticle had an average diameter of about 200 nm and displayed superparamagnetism with a saturation magnetization value of 40.5 emu g(-1), it also exhibited a large surface area of 396.10 m(2) g(-1).	Nitrogen	66-74	hydroxyacid oxidase 1	Homo sapiens	183-186
25490879-3	2015	In the process, the indole unit of L1 is deprotonated by the metal alkyl species and the imino C=N group is transferred to the amido group by alkyl CH2 SiMe3 insertion, affording a new dianionic ligand that bridges two metal alkyl units in mu-eta(2) :eta(1) :eta(1) bonding modes, forming the dinuclear rare-earth metal alkyl complexes.	Nitrogen	97-98	secreted phosphoprotein 1	Homo sapiens	259-265
25240298-12	2015	In TNBS-treated mice, supplementation with NS significantly reduced weight loss, and serum proinflammatory cytokine levels (IL-2, IL-6, and IL-12, TNFalpha, IFNgamma) compared with the TNBS group.	Nitrogen	43-45	interleukin 2	Mus musculus	124-128
26612539-6	2015	Rather than classical stacking interactions that occur across nitrogen bases and aromatic amino acids on ribonucleoprotein sites, moderate-affinity hydrogen bonding network between the nitrogen bases in the stem-loop RNA and a concave face on the RRM surface primarily mediate TAF15-RRM RNA interaction.	Nitrogen	185-193	TATA-box binding protein associated factor 15	Homo sapiens	277-282
24428683-6	2014	Furthermore, CYP2C19 seems to be an important enzyme in the N-demethylation of aminopyrine, and polymorphisms in this gene may influence breath test values, which should be kept in mind when performing the (13) C(2) -aminopyrine breath test in clinical practice.	Nitrogen	60-61	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	13-20
25503386-9	2015	Our results highlight the need to include UGT2B10 when screening the human UGTs for the enzymes involved in the glucuronidation of a new compound, particularly when there is a possibility of N-glucuronidation.	Nitrogen	191-192	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	42-49
24593295-9	2014	There was a direct correlation between n-3 PUFAs consumption and serum BDNF levels, which remained significant even after accounting for potential confounders.	Nitrogen	29-30	brain derived neurotrophic factor	Homo sapiens	71-75
24598749-0	2014	Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.	Nitrogen	106-114	farnesyl diphosphate synthase	Homo sapiens	73-102
26463131-3	2015	The results of the SAR developed highlight the relationship between the sulfonamide and quinoline nitrogen, while also suggesting that an aryl substituent at the 5-position of the quinoline ring contributes to the potency in the interaction assay.	Nitrogen	98-106	sarcosine dehydrogenase	Homo sapiens	19-22
25513968-6	2015	Compared to JDTic, the N-fluoropropyl derivative 2 bound to KOR with an only 4-fold lower affinity and a higher selectivity relative to MOR and DOR [Ki(kappa) = 1.6 nM; Ki(mu)/Ki(kappa) = 12; Ki(delta)/Ki(kappa) = 159 for 2versus Ki(kappa) = 0.42 nM; Ki(mu)/Ki(kappa) = 9; Ki(delta)/Ki(kappa) = 85 for JDTic].	Nitrogen	23-24	opioid receptor mu 1	Homo sapiens	136-139
26613462-5	2015	We also show for the first time that the spin state of single TM atoms systematically varies with the coordination of neighboring nitrogen or oxygen atoms.	Nitrogen	130-138	spindlin 1	Homo sapiens	41-45
24361613-6	2014	RESULTS: Compared to saline, Trx or N-acetylcysteine, an intravenous administration of HSA-Trx attenuated the cisplatin-induced elevation in serum creatinine, blood urea nitrogen and urinary N-acetyl-beta-d-glucosaminidase along with the decrease in creatinine clearance.	Nitrogen	170-178	thioredoxin 1	Mus musculus	91-94
25653610-3	2014	The nogo effect of N2 related to conflict monitoring was similar between two groups.	Nitrogen	19-21	reticulon 4	Homo sapiens	4-8
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	130-132	T cell receptor alpha locus	Homo sapiens	95-98
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	130-132	T cell receptor alpha locus	Homo sapiens	123-126
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	130-132	T cell receptor alpha locus	Homo sapiens	123-126
26461041-1	2015	We show that changing the number and position of nitrogen atoms in the heteroatomic core of a pyrazolopyrimidine acetamide is sufficient to induce complex binding to wild type human TSPO.	Nitrogen	49-57	translocator protein	Homo sapiens	182-186
26370074-7	2015	MLV released from cells carrying N-acyl-modified sialic acids displayed strikingly different capacities for Siglec-1-mediated capture and trans-infection; N-butanoyl, N-isobutanoyl, N-glycolyl, or N-pentanoyl side chain modifications resulted in up to 92 and 80% reduction of virus particle capture and trans-infection, respectively, whereas N-propanoyl or N-cyclopropylcarbamyl side chains had no effect.	Nitrogen	33-34	sialic acid binding Ig-like lectin 1, sialoadhesin	Mus musculus	108-116
28649550-9	2015	These variant FMO3 proteins recombinantly expressed in Escherichia coli membranes exhibited decreased N-oxygenation activities toward trimethylamine and benzydamine.	Nitrogen	102-103	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	14-18
24900839-1	2014	The K-26 family of bacterial secondary metabolites are N-modified tripeptides terminated by an unusual phosphonate analog of tyrosine.	Nitrogen	55-56	keratin 26	Homo sapiens	4-8
25426571-3	2015	The formation of DD1 is found to be promoted by the presence of nitrogen and can be suppressed by reducing the strain between the core and shell layers, as well as by protecting the optically active shell by an outer passivating shell.	Nitrogen	64-72	aldo-keto reductase family 1 member C1	Homo sapiens	17-20
24189322-6	2014	NQO1(-/-) mice showed increased blood urea nitrogen and creatinine levels, tubular damage, oxidative stress, and apoptosis.	Nitrogen	43-51	NAD(P)H dehydrogenase, quinone 1	Mus musculus	0-4
26102310-4	2015	NH4 Cl increased Mrp4 mRNA and protein levels in astrocytes in a dose- and time-dependent manner up to threefold after 72 h of exposure and concurrently inhibited N-glycosylation of Mrp4 protein.	Nitrogen	0-1	ATP binding cassette subfamily C member 4	Homo sapiens	17-21
26102310-4	2015	NH4 Cl increased Mrp4 mRNA and protein levels in astrocytes in a dose- and time-dependent manner up to threefold after 72 h of exposure and concurrently inhibited N-glycosylation of Mrp4 protein.	Nitrogen	0-1	ATP binding cassette subfamily C member 4	Homo sapiens	182-186
24367020-7	2014	Similar to miR826, miR5090 is induced by nitrogen starvation.	Nitrogen	41-49	MIR826a	Arabidopsis thaliana	11-17
25385303-8	2015	RESULTS: ANP treatment significantly attenuated cisplatin-induced increases in serum blood urea nitrogen and creatinine, urine albumin/creatinine, and renal expression of IL-1beta, IL-6, intercellular adhesion molecule-1, and monocyte chemoattractant protein-1 mRNAs.	Nitrogen	96-104	natriuretic peptide type A	Mus musculus	9-12
24072481-3	2014	Endothelial protein C receptor (EPCR) is an N-glycosylated type I membrane protein that enhances the activation of protein C. However, the effects of EPCR and protein C in AD are still unknown.	Nitrogen	44-45	protein C receptor, endothelial	Mus musculus	0-30
24072481-3	2014	Endothelial protein C receptor (EPCR) is an N-glycosylated type I membrane protein that enhances the activation of protein C. However, the effects of EPCR and protein C in AD are still unknown.	Nitrogen	44-45	protein C receptor, endothelial	Mus musculus	32-36
26531304-0	2015	A theoretical investigation into the strength of N-NO2 bonds, ring strain and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX.	Nitrogen	177-185	radixin	Homo sapiens	230-233
26531304-1	2015	Changes in N-NO2 bond strength, ring strain energy and electrostatic potential upon formation of intermolecular H-bonds between HF and the nitro group in nitrogen heterocyclic rings C n H2n N-NO2 (n = 2-5), RDX and HMX were investigated using DFT-B3LYP and MP2(full) methods with the 6-311++G(2df,2p) and aug-cc-pVTZ basis sets.	Nitrogen	154-162	radixin	Homo sapiens	207-210
26497777-1	2015	We consider an electronic spin, such as a nitrogen-vacancy center in diamond, weakly coupled to a large number of nuclear spins, and subjected to the Rabi driving with a periodically alternating phase.	Nitrogen	42-50	spindlin 1	Homo sapiens	26-30
24819279-4	2015	Mice with renal I/R injury showed a significant increase in blood urea nitrogen and creatinine levels, and these effects were decreased by EPC transplantation.	Nitrogen	71-79	transcription factor 21	Mus musculus	139-142
26447991-9	2015	IFP-1, -3, and -5, which are synthesized by MW-assisted conditions, showed an enhancement of N2 and CO2, compared to the analogous conventional electrical (CE) heating method based materials due to crystal defects.	Nitrogen	93-95	tripartite motif containing 34	Homo sapiens	0-17
24567814-7	2014	RESULTS: In comparison to the control group, the NP + NS group showed a significant increase of phospho-p38 and p38 MAPK, as well as of the proinflammatory cytokines, tumor necrosis factor alpha (TNFalpha), and intercellular adhesion molecule 1 (ICAM1).	Nitrogen	54-56	intercellular adhesion molecule 1	Rattus norvegicus	211-244
24567814-7	2014	RESULTS: In comparison to the control group, the NP + NS group showed a significant increase of phospho-p38 and p38 MAPK, as well as of the proinflammatory cytokines, tumor necrosis factor alpha (TNFalpha), and intercellular adhesion molecule 1 (ICAM1).	Nitrogen	54-56	intercellular adhesion molecule 1	Rattus norvegicus	246-251
26632221-5	2015	Quartz-crystal microbalance-dissipation measurements suggested that ionic interaction between the oxygen of the terminal hydroxyl groups of titanium and the nitrogen of fibronectin was important for fibronectin immobilization.	Nitrogen	157-165	fibronectin 1	Rattus norvegicus	169-180
24903210-1	2014	OBJECTIVE: The aim of this study was to investigate the presence of anti-carbonic anhydrase (CA II) autoantibodies in patients with end-stage renal disease (ESRD) and relationships between the autoantibody titers and ghrelin, glucose, blood urea nitrogen (BUN) and creatinine.	Nitrogen	246-254	carbonic anhydrase 2	Homo sapiens	93-98
24476960-5	2014	Under poor nitrogen supply, Npr1 enables Mep2 S457 phosphorylation and thus ammonium transport activity.	Nitrogen	11-19	ammonium permease MEP2	Saccharomyces cerevisiae S288C	41-45
24476960-6	2014	Supplementation of the preferred nitrogen source glutamine leads to Mep2 inactivation and instant S457 dephosphorylation via plasma membrane Psr1 and Psr2 redundant phosphatases.	Nitrogen	33-41	ammonium permease MEP2	Saccharomyces cerevisiae S288C	68-72
26870803-3	2015	SYK enhances the formation of SGs, is active within the resulting SGs and stimulates the production of reactive oxygen and nitrogen species that are toxic to neuronal cells.	Nitrogen	123-131	spleen associated tyrosine kinase	Homo sapiens	0-3
26138512-0	2015	High metabolic N-oxidation of voriconazole in a patient with refractory aspergillosis and CYP2C19*17/*17 genotype.	Nitrogen	15-16	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	90-97
26632221-5	2015	Quartz-crystal microbalance-dissipation measurements suggested that ionic interaction between the oxygen of the terminal hydroxyl groups of titanium and the nitrogen of fibronectin was important for fibronectin immobilization.	Nitrogen	157-165	fibronectin 1	Rattus norvegicus	199-210
26169738-0	2015	N-Glycosylation Fingerprinting of Viral Glycoproteins by xCGE-LIF.	Nitrogen	0-1	LIF interleukin 6 family cytokine	Homo sapiens	62-65
26958622-3	2015	Meanwhile, we performed MALDI-QIT-TOF mass spectrometry-based N-glycomic analysis of the recombinant human SP-D produced in murine myeloma cells.	Nitrogen	62-63	surfactant protein D	Homo sapiens	107-111
24521937-9	2014	We hypothesize that rapid activation of asparagine synthetase in susceptible tomato may play a dual role in promoting Botrytis cinerea pathogenesis by providing a rich source of N for the pathogen, on the one hand, and facilitating pathogen-induced host senescence, on the other.	Nitrogen	178-179	asparagine synthetase	Solanum lycopersicum	40-61
26169738-4	2015	Here, we provide a protocol for N-glycosylation fingerprinting utilizing high performance multiplexed capillary gel electrophoresis with laser-induced fluorescence detection (xCGE-LIF) technology.	Nitrogen	32-33	LIF interleukin 6 family cytokine	Homo sapiens	180-183
25187293-3	2014	Plant-specific N-glycosylation patterns elaborated within the Golgi complex are a major limitation of using plants to produce biopharmaceuticals as the presence of beta1,2 xylose and/or alpha1,3 fucose residues on the recombinant glycoprotein can render the product immunogenic if administrated parenterally.	Nitrogen	15-16	adrenoceptor alpha 1D	Homo sapiens	186-194
24379273-10	2013	The receptor site for the EBA-140 ligand was suggested to be a cluster of N-and O-linked sialylated glycans on the GPC molecule, whose conformation is dependent on the polypeptide chain region composed of amino acid residues 36-63.	Nitrogen	74-75	glycophorin C (Gerbich blood group)	Homo sapiens	115-118
24211831-2	2013	CD45RABC is heavily O-glycosylated and N-glycosylated, while CD45RO is only N-glycosylated.	Nitrogen	39-40	protein tyrosine phosphatase receptor type C	Homo sapiens	0-4
24148083-3	2013	TS analogues of MTAP incorporate a cationic nitrogen and a protonated 9-deazaadenine leaving group, which are mimics of the ribocation transition state.	Nitrogen	44-52	methylthioadenosine phosphorylase	Homo sapiens	16-20
26594472-3	2015	Further, the O atom of the benzo-furan ring is syn to the N atom of the oxime group.	Nitrogen	58-59	synemin	Homo sapiens	47-50
26314394-1	2015	Farnesyl pyrophosphate synthase (FPPS) catalyzes the condensation of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate to FPP and is known to be a molecular target of osteoporosis drugs, such as risedronate (RIS), which is a nitrogen-containing bisphosphonate.	Nitrogen	239-247	farnesyl diphosphate synthase	Homo sapiens	0-31
26314394-1	2015	Farnesyl pyrophosphate synthase (FPPS) catalyzes the condensation of isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate to FPP and is known to be a molecular target of osteoporosis drugs, such as risedronate (RIS), which is a nitrogen-containing bisphosphonate.	Nitrogen	239-247	farnesyl diphosphate synthase	Homo sapiens	33-37
26305678-0	2015	Improved Environmental Life Cycle Assessment of Crop Production at the Catchment Scale via a Process-Based Nitrogen Simulation Model.	Nitrogen	107-115	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	48-52
26305678-1	2015	One of the major challenges in environmental life cycle assessment (LCA) of crop production is the nonlinearity between nitrogen (N) fertilizer inputs and on-site N emissions resulting from complex biogeochemical processes.	Nitrogen	120-128	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	76-80
25195029-13	2014	Due to the low reduction in hydraulic conductivity, GAC-treated water quality was used to set pre-treatment targets for ASR injection of turbidity &lt;0.6 NTU, membrane filtration index (MFI) &lt; 2 s/L(2), biodegradable dissolved organic carbon (BDOC) &lt; 0.2 mg/L, total nitrogen &lt; 0.3 mg/L and residual chlorine &gt; 0.2 mg/L.	Nitrogen	274-282	glutaminase	Homo sapiens	52-55
26224316-0	2015	N-glycosylation controls the function of junctional adhesion molecule-A.	Nitrogen	0-1	F11 receptor	Homo sapiens	41-71
26224316-6	2015	N-glycosylation of JAM-A is required for the protein"s ability to reinforce barrier function and contributes to Rap1 activity.	Nitrogen	0-1	F11 receptor	Homo sapiens	19-24
26224316-8	2015	Finally, we show that N-glycosylation of JAM-A regulates leukocyte adhesion and LFA-1 binding.	Nitrogen	22-23	F11 receptor	Homo sapiens	41-46
26224316-9	2015	These findings identify N-glycosylation as critical for JAM-A"s many functions.	Nitrogen	24-25	F11 receptor	Homo sapiens	56-61
23520037-5	2013	As the first example of such study of N-substituted small peptides, our results suggest that the substitute group at the N-terminal and the length of peptides significantly affect the position of the cleavage site on the oligopeptides, which provides a useful insight for the design of small peptide derivatives as the substrates of MMP-9.	Nitrogen	38-39	matrix metallopeptidase 9	Homo sapiens	333-338
24055074-7	2013	These observations warrant examination of bis-ortho-substituted five-membered nitrogen heterocycles as dual ALK-5/HSP-70 inhibitors for anti-cancer drug development.	Nitrogen	78-86	heat shock protein family A (Hsp70) member 4	Homo sapiens	114-120
25300029-2	2014	In this study we have utilized a powerful nano-HPLC-mass spectrometric approach to characterize patterns of normal and abnormal N-linked glycosylation of alpha3 integrin subunit in Pkd1(-/-) cells derived from mouse kidneys.	Nitrogen	128-129	polycystin 1, transient receptor potential channel interacting	Mus musculus	181-185
24013633-8	2013	The feaR gene is upregulated by carbon or nitrogen limitation, which we propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assimilation control protein (NAC), respectively.	Nitrogen	42-50	catabolite gene activator protein	Escherichia coli	115-142
24013633-8	2013	The feaR gene is upregulated by carbon or nitrogen limitation, which we propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assimilation control protein (NAC), respectively.	Nitrogen	42-50	catabolite gene activator protein	Escherichia coli	144-147
24013633-8	2013	The feaR gene is upregulated by carbon or nitrogen limitation, which we propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assimilation control protein (NAC), respectively.	Nitrogen	157-165	catabolite gene activator protein	Escherichia coli	115-142
24013633-8	2013	The feaR gene is upregulated by carbon or nitrogen limitation, which we propose reflects regulation of feaR by the cyclic AMP receptor protein (CRP) and the nitrogen assimilation control protein (NAC), respectively.	Nitrogen	157-165	catabolite gene activator protein	Escherichia coli	144-147
24013450-1	2013	Quantum chemical calculations are performed to study the interplay between halogen nitrogen and halogen carbene interactions in NCX NCX CH2 complexes, where X = F, Cl, Br and I. Molecular geometries and interaction energies of dyads and triads are investigated at the MP2/aug-cc-pVTZ level of theory.	Nitrogen	83-91	T cell leukemia homeobox 2	Homo sapiens	128-131
25998389-8	2015	From these experiments, we concluded that each of these three genes were involved in N-linked sialylation and ST3GAL4 may play the critical role in glycoprotein sialylation of recombinant proteins such as EPO.	Nitrogen	85-86	erythropoietin	Cricetulus griseus	205-208
26094740-1	2015	The combination of a catalytic amount of Cu(OTf)2 and less than a stoichiometric amount of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) under an O2 atmosphere effectively promoted the N-nitrosation of both secondary aromatic/aliphatic amines and tertiary aromatic amines with nitromethane (CH3NO2) leading to the preparation of N-nitrosamine derivatives.	Nitrogen	180-181	POU class 2 homeobox 2	Homo sapiens	41-49
24863482-4	2014	Our data show that a major long term effect of Miglustat is its interference with N-glycosylation of the proteins in the ER leading to a delay in the trafficking of sucrase-isomaltase.	Nitrogen	82-83	sucrase-isomaltase	Homo sapiens	165-183
26135639-0	2015	A Terminal N2 Complex of High-Spin Iron(I) in a Weak, Trigonal Ligand Field.	Nitrogen	11-13	spindlin 1	Homo sapiens	30-34
26135639-3	2015	Given that the nitrogenase active site uses weak-field sulfide ligands to stabilize its reactive Fe center(s), N2 binding to high-spin Fe is of great interest.	Nitrogen	111-113	spindlin 1	Homo sapiens	130-134
24028846-3	2013	Application of Glc, Fru, or Suc, as well as cold, osmotic stress, or low nitrogen, provoke the down-regulation of SWEET16 messenger RNA accumulation.	Nitrogen	73-81	Nodulin MtN3 family protein	Arabidopsis thaliana	114-121
24028846-9	2013	35SPro:SWEET16 plants exhibited increased growth efficiency when cultivated on soil and showed improved nitrogen use efficiency when nitrate was sufficiently available, while under conditions of limiting nitrogen, wild-type biomasses were higher than those of 35SPro:SWEET16 plants.	Nitrogen	104-112	Nodulin MtN3 family protein	Arabidopsis thaliana	7-14
24028846-9	2013	35SPro:SWEET16 plants exhibited increased growth efficiency when cultivated on soil and showed improved nitrogen use efficiency when nitrate was sufficiently available, while under conditions of limiting nitrogen, wild-type biomasses were higher than those of 35SPro:SWEET16 plants.	Nitrogen	204-212	Nodulin MtN3 family protein	Arabidopsis thaliana	7-14
24088297-1	2013	BACKGROUND: Dietary supplementation with botanical oils that contain n-6 and n-3 eighteen carbon chain (18C)-PUFA such as gamma linolenic acid (GLA, 18:3n-6), stearidonic acid (SDA, 18:4n-3) and alpha linolenic acid (ALA, 18:3n-3) have been shown to impact PUFA metabolism, alter inflammatory processes including arachidonic acid (AA) metabolism and improve inflammatory disorders.	Nitrogen	28-29	pumilio RNA binding family member 3	Homo sapiens	109-113
24088297-1	2013	BACKGROUND: Dietary supplementation with botanical oils that contain n-6 and n-3 eighteen carbon chain (18C)-PUFA such as gamma linolenic acid (GLA, 18:3n-6), stearidonic acid (SDA, 18:4n-3) and alpha linolenic acid (ALA, 18:3n-3) have been shown to impact PUFA metabolism, alter inflammatory processes including arachidonic acid (AA) metabolism and improve inflammatory disorders.	Nitrogen	28-29	pumilio RNA binding family member 3	Homo sapiens	257-261
26058329-2	2015	N-Substituted conjugates of cyclam and cyclen with bioisosteric phosphonate groups displayed good activities toward T-cell protein tyrosine phosphatase with IC50 values in the micromolar to nanomolar range and showed selectivity over PTP1B, CD45, SHP2, and PTPbeta.	Nitrogen	0-1	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	234-239
26058329-2	2015	N-Substituted conjugates of cyclam and cyclen with bioisosteric phosphonate groups displayed good activities toward T-cell protein tyrosine phosphatase with IC50 values in the micromolar to nanomolar range and showed selectivity over PTP1B, CD45, SHP2, and PTPbeta.	Nitrogen	0-1	protein tyrosine phosphatase receptor type C	Homo sapiens	241-245
26058329-2	2015	N-Substituted conjugates of cyclam and cyclen with bioisosteric phosphonate groups displayed good activities toward T-cell protein tyrosine phosphatase with IC50 values in the micromolar to nanomolar range and showed selectivity over PTP1B, CD45, SHP2, and PTPbeta.	Nitrogen	0-1	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	247-251
25944577-8	2015	MMP-9 activity correlated with urea nitrogen (r = 0 42; P &lt; 0 05) and LVEF (r = -0 73; P &lt; 0 01).	Nitrogen	36-44	matrix metallopeptidase 9	Homo sapiens	0-5
23480350-0	2013	Regulation of nitrate reduction in Arabidopsis WT and hxk1 mutant under C and N metabolites.	Nitrogen	78-79	hexokinase 1	Arabidopsis thaliana	54-58
25577832-4	2014	Bioinformatic analysis indicated that the highly expressed SPP1 gene encoded 314 amino acids and contained 2 N-glycosylation sites, 8 casein kinase II phosphorylation sites and 3 protein kinase C phosphorylation sites, playing essential roles in extracellular matrix (ECM) binding, ossification, osteoblast differentiation, cell adhesion, PI3K-Akt signaling pathway, focal adhesion, Toll-like receptor signaling pathway, and ECM-receptor interaction.	Nitrogen	109-110	secreted phosphoprotein 1	Homo sapiens	59-63
23907821-3	2013	n-3 PUFA intake was estimated using the nitrogen stable isotope ratio (delta(15) N) of erythrocytes.	Nitrogen	40-48	pumilio RNA binding family member 3	Homo sapiens	4-8
26717758-2	2015	The applications of different types of spectral radiometer, especially for international general used Cropscan multispectral radiometer, for predicting crop canopy leaf area index under different growth stage, biomass, nitrogen, chlorophyll and yield, and monitoring plant diseases and insect pests were summarized based on crop group information acquisition methods in recent years.	Nitrogen	219-227	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	152-156
25295708-0	2014	Sc(OTf)3-catalyzed transfer diazenylation of 1,3-dicarbonyls with triazenes via N-N bond cleavage.	Nitrogen	80-81	POU class 5 homeobox 1	Homo sapiens	0-8
25733617-1	2015	UNLABELLED: Molybdenum nitrogenase (Nif), which catalyzes the reduction of dinitrogen to ammonium, has modulated the availability of fixed nitrogen in the biosphere since early in Earth"s history.	Nitrogen	75-85	S100 calcium binding protein A9	Homo sapiens	36-39
25733617-1	2015	UNLABELLED: Molybdenum nitrogenase (Nif), which catalyzes the reduction of dinitrogen to ammonium, has modulated the availability of fixed nitrogen in the biosphere since early in Earth"s history.	Nitrogen	23-31	S100 calcium binding protein A9	Homo sapiens	36-39
25733617-3	2015	Aerobic bacteria that fix N2 have adapted a number of strategies to protect Nif from inactivation by O2, including spatial and temporal segregation of Nif from O2 and respiratory consumption of O2.	Nitrogen	26-28	S100 calcium binding protein A9	Homo sapiens	76-79
25733617-3	2015	Aerobic bacteria that fix N2 have adapted a number of strategies to protect Nif from inactivation by O2, including spatial and temporal segregation of Nif from O2 and respiratory consumption of O2.	Nitrogen	26-28	S100 calcium binding protein A9	Homo sapiens	151-154
25733617-10	2015	IMPORTANCE: Molybdenum nitrogenase (Nif), which catalyzes the reduction of dinitrogen to ammonium, has modulated the availability of fixed nitrogen in the biosphere since early in Earth"s history.	Nitrogen	75-85	S100 calcium binding protein A9	Homo sapiens	36-39
23824793-9	2013	CD4 independence and neutralization sensitivity were both conferred by Env amino acid changes E84K and D470N that arose independently in multiple animals, with the latter introducing a potential N-linked glycosylation site within a predicted CD4-binding pocket of gp120.	Nitrogen	107-108	endogenous retrovirus group K member 20	Homo sapiens	71-74
25295708-0	2014	Sc(OTf)3-catalyzed transfer diazenylation of 1,3-dicarbonyls with triazenes via N-N bond cleavage.	Nitrogen	82-83	POU class 5 homeobox 1	Homo sapiens	0-8
25733617-10	2015	IMPORTANCE: Molybdenum nitrogenase (Nif), which catalyzes the reduction of dinitrogen to ammonium, has modulated the availability of fixed nitrogen in the biosphere since early in Earth"s history.	Nitrogen	23-31	S100 calcium binding protein A9	Homo sapiens	36-39
23977108-0	2013	RuvBL2 is involved in histone deacetylase inhibitor PCI-24781-induced cell death in SK-N-DZ neuroblastoma cells.	Nitrogen	86-88	histone deacetylase 9	Homo sapiens	22-41
25785825-1	2015	The palladium-catalyzed reaction of 2,3,3-trifluoroallyl esters with several types of amines afforded trifluoromethylenamines, which were formed by the addition of a nitrogen nucleophile at the C-2 position and the intramolecular construction of the trifluoromethyl group via the fluorine atom shift from the C-2 to the C-3 position.	Nitrogen	166-174	complement C3	Homo sapiens	320-323
25295708-1	2014	A new and efficient method for diazenylation reactions was developed with a Sc(OTf)3-catalyzed nitrogen-nitrogen bond cleavage process with triazenes.	Nitrogen	95-103	POU class 5 homeobox 1	Homo sapiens	76-84
25295708-1	2014	A new and efficient method for diazenylation reactions was developed with a Sc(OTf)3-catalyzed nitrogen-nitrogen bond cleavage process with triazenes.	Nitrogen	104-112	POU class 5 homeobox 1	Homo sapiens	76-84
28811451-4	2013	The geometry of the Ca(II) ion is a distorted CaNO6 pengonal bipyramid, arising from its coordination by four water molecules, one nitrogen atom of 4,4"-bipyridyl molecule, and two oxygen atoms from two L ligands.	Nitrogen	131-139	carbonic anhydrase 2	Homo sapiens	20-26
25157565-3	2014	Here, to fill this deficiency, we conducted detailed analyses of the SERS of pyridine adsorbed through N-Ag bonding on the homonuclear diatomic metal cluster Ag2 and heteronuclear diatomic metal clusters of AuAg and CuAg, as well as the involved charge transfer under an intracluster excitation, based on calculations using time-dependent density functional theory with a short-time approximation for the Raman cross-section.	Nitrogen	103-104	anterior gradient 2, protein disulphide isomerase family member	Homo sapiens	158-161
23818625-2	2013	In all these organisms, P(II) proteins coordinate many facets of nitrogen metabolism by interacting with and regulating the activities of enzymes, transcription factors, and membrane transport proteins.	Nitrogen	65-73	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	24-29
23897470-12	2013	These findings suggest that yNit2 may have broad biological roles in yeast, especially in regard to nitrogen homeostasis, and provide a framework for the elucidation of the substrate specificity and biological role of mammalian Nit1.	Nitrogen	100-108	nitrilase 1	Homo sapiens	228-232
25723098-7	2015	The overall results demonstrated that the improved oral bioavailability of RES by Lab-N was mainly attributable to the inhibition of intestinal glucuronidation by the presence of UGT inhibitory excipient.	Nitrogen	86-87	UDP glycosyltransferase 2 family, polypeptide B	Rattus norvegicus	179-182
25659749-9	2015	These results show that nitrogen availability regulates the leaf and root cysteine protease, VPE and cystatin transcript profiles in a manner that is in some cases influenced by ectopic OCI expression.	Nitrogen	24-32	cysteine proteinase inhibitor	Glycine max	101-109
25835533-3	2015	In this study, we show that vGPCR undergoes extensive N-linked glycosylation within the extracellular domains, specifically asparagines 18, 22, 31 and 202.	Nitrogen	54-55	K14	Human gammaherpesvirus 8	28-33
25835533-4	2015	An immunofluorescence assay demonstrates that N-linked glycosylation are necessary for vGPCR trafficking to the cellular membrane.	Nitrogen	46-47	K14	Human gammaherpesvirus 8	87-92
25045021-1	2014	The mitochondrial amidoxime reducing component (mARC) is a molybdenum-containing enzyme and capable of reducing N-hydroxylated structures such as amidoxime prodrugs.	Nitrogen	112-113	activity regulated cytoskeletal-associated protein	Mus musculus	48-52
25576917-4	2015	When present in the culture medium,ammonium impaired the consumption of the auxotrophy-complementing amino acids and caused in an improper cell cycle arrest of the culture.TOR1 deletion reverted ammonium effects both in amino acid restricted and non-restricted cultures, whereas, Ras2p and Sch9p seem to have only a milder effect in the mediation of ammonium toxicity under amino acid restriction and no effect on non-restricted cultures.Our studies highlight ammonium as a key effector in the nutritional equilibrium between rich and essential nitrogen sources and glucose required for longevity promotion.	Nitrogen	545-553	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	172-176
23703614-3	2013	Previously, we reported that canonical Wnt signaling functions in a positive feedback loop with the DPAGT1 gene, a principal regulator of the metabolic pathway of protein N-glycosylation, to hyperglycosylate E-cadherin and reduce intercellular adhesion.	Nitrogen	171-172	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	100-106
23703614-6	2013	Partial inhibition of DPAGT1 expression in OSCC CAL27 cells reduced CTHRC1 abundance by increasing protein turnover, indicating that N-glycosylation stabilizes CTHRC1.	Nitrogen	133-134	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	22-28
23703614-9	2013	We propose that in OSCC, dysregulation of canonical Wnt signaling and DPAGT1-dependent N-glycosylation induces CTHRC1, thereby driving OSCC cell migration and tumor spread.	Nitrogen	87-88	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	70-76
23766555-5	2013	Electron spin echo envelope modulation spectroscopy with Fourier transform of the modulated spin echo decay shows a strong coordination by nitrogen atoms and excludes the coordination by phosphate and/or amide groups.	Nitrogen	139-147	spindlin 1	Homo sapiens	9-13
23766555-5	2013	Electron spin echo envelope modulation spectroscopy with Fourier transform of the modulated spin echo decay shows a strong coordination by nitrogen atoms and excludes the coordination by phosphate and/or amide groups.	Nitrogen	139-147	spindlin 1	Homo sapiens	92-96
25731074-1	2015	A preceramic polymer route from Ti-based inorganic-organic hybrid networks provides electroconductive N-doped reduced titanium oxides (TinO2n-1) and titanium oxynitrides (TiOxNy) with a monolithic shape as well as well-defined porous structures.	Nitrogen	102-103	mex-3 RNA binding family member D	Homo sapiens	135-139
25045021-3	2014	All groups are reduced by mARC proteins, and the enzymes are therefore involved in the interconversion of N-oxygenated metabolites originating from cytochrome P450s and flavin-containing monooxygenases.	Nitrogen	106-107	activity regulated cytoskeletal-associated protein	Mus musculus	26-30
25698617-7	2015	Interestingly, the 2-hydroxy-2-pyrrolidine-2-yl-acetic acid rac-(u)-13d containing 2-{[tris(4-methoxyphenyl)]methoxy} ethyl group at the nitrogen atom of the pyrrolidine ring showed high potency at mGAT4 and a comparatively better selectivity for this protein (&gt;15 against mGAT3) than the well known mGAT4 uptake inhibitor (S)-SNAP-5114.	Nitrogen	137-145	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	Mus musculus	198-203
25698617-7	2015	Interestingly, the 2-hydroxy-2-pyrrolidine-2-yl-acetic acid rac-(u)-13d containing 2-{[tris(4-methoxyphenyl)]methoxy} ethyl group at the nitrogen atom of the pyrrolidine ring showed high potency at mGAT4 and a comparatively better selectivity for this protein (&gt;15 against mGAT3) than the well known mGAT4 uptake inhibitor (S)-SNAP-5114.	Nitrogen	137-145	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	Mus musculus	276-281
24789683-1	2014	The tumor suppressor gene nitrogen permease regulator-like 2(NPRL2) NPRL2 expressed obviously in many normal human tissues, but reduced in expression in many human tumors significantly.	Nitrogen	26-34	NPR2 like, GATOR1 complex subunit	Homo sapiens	61-66
25698617-7	2015	Interestingly, the 2-hydroxy-2-pyrrolidine-2-yl-acetic acid rac-(u)-13d containing 2-{[tris(4-methoxyphenyl)]methoxy} ethyl group at the nitrogen atom of the pyrrolidine ring showed high potency at mGAT4 and a comparatively better selectivity for this protein (&gt;15 against mGAT3) than the well known mGAT4 uptake inhibitor (S)-SNAP-5114.	Nitrogen	137-145	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	Mus musculus	303-308
25701250-6	2015	An analysis of the SARs for MAO inhibition by 3-chloro-1H-indole-5,6-dicarbonitriles showed that methylation of the indole nitrogen eliminates MAO-B inhibition activity, and replacement of the 2-phenyl ring with the thienyl results in a 9-fold reduction of MAO-B inhibition activity.	Nitrogen	123-131	monoamine oxidase B	Homo sapiens	143-148
25701250-6	2015	An analysis of the SARs for MAO inhibition by 3-chloro-1H-indole-5,6-dicarbonitriles showed that methylation of the indole nitrogen eliminates MAO-B inhibition activity, and replacement of the 2-phenyl ring with the thienyl results in a 9-fold reduction of MAO-B inhibition activity.	Nitrogen	123-131	monoamine oxidase B	Homo sapiens	257-262
23688261-1	2013	After the hydrolysis of the N-glycosyl bond between a damaged base and C1" of a deoxyribosyl moiety of DNA, human alkyladenine DNA glycosylase (AAG) and Escherichia coli 3-methyladenine DNA glycosylase II (AlkA) bind tightly to their abasic DNA products, potentially protecting these reactive species.	Nitrogen	28-29	N-methylpurine DNA glycosylase	Homo sapiens	114-142
23762435-7	2013	Targeted ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) based metabolomic analysis of the breast tissue extracts showed the presence of adenine adducts of estrogens, E1(E2)-9-N-Ade, along with other estrogen related metabolites.	Nitrogen	206-207	cystatin 12, pseudogene	Homo sapiens	197-205
24789683-1	2014	The tumor suppressor gene nitrogen permease regulator-like 2(NPRL2) NPRL2 expressed obviously in many normal human tissues, but reduced in expression in many human tumors significantly.	Nitrogen	26-34	NPR2 like, GATOR1 complex subunit	Homo sapiens	68-73
23567996-4	2013	Then, the activities of FMO3 variants in human liver microsomes and the activities of recombinantly expressed FMO3 variant proteins with respect to the oxygenation of nitrogen- and sulfur-containing drugs were summarized and the potential for drug interactions was demonstrated.	Nitrogen	167-175	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	110-114
25576393-11	2015	PPARalpha via HNF4alpha maintains body protein metabolic homeostasis by down-regulating genes involved in amino acid catabolism for preserving body nitrogen.	Nitrogen	148-156	hepatic nuclear factor 4, alpha	Mus musculus	14-23
25561468-5	2015	Perturbation of ME ICA512 beta2-strand N-glycosylation upon S508A replacement allows for proICA512 dimerization, O-glycosylation, targeting to granules, and conversion, which are instead precluded upon G553D replacement in the ME ICA512 beta4-strand.	Nitrogen	39-40	protein tyrosine phosphatase receptor type N	Homo sapiens	19-25
25561468-5	2015	Perturbation of ME ICA512 beta2-strand N-glycosylation upon S508A replacement allows for proICA512 dimerization, O-glycosylation, targeting to granules, and conversion, which are instead precluded upon G553D replacement in the ME ICA512 beta4-strand.	Nitrogen	39-40	protein tyrosine phosphatase receptor type N	Homo sapiens	92-98
25245409-7	2014	Analysis of recombinant MLP showed that it is an N-linked glycosylated protein and biophysical studies predicted that MLP is an amphipathic, alpha-helical protein, a typical feature of antimicrobial proteins.	Nitrogen	49-50	protein LEG1 homolog	Ornithorhynchus anatinus	24-27
25604530-5	2015	Moreover, 35S:GRF5 plants show delayed leaf senescence and are more tolerant for growth on nitrogen-depleted medium.	Nitrogen	91-99	general regulatory factor 5	Arabidopsis thaliana	14-18
25604530-8	2015	Evidence is provided that GRF5 and cytokinins synergistically enhance cell division and chlorophyll retention after dark-induced senescence, which suggests that they also cooperate to stimulate chloroplast division and nitrogen assimilation.	Nitrogen	219-227	general regulatory factor 5	Arabidopsis thaliana	26-30
23591138-2	2013	DPAGT1 encodes an early component of the N-linked glycosylation pathway.	Nitrogen	41-42	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	0-6
25028064-1	2014	van der Waals complexes of sulfur dioxide (SO2) with oxygen (O2) and nitrogen (N2) have been investigated by using MP2 and aug-cc-pVXZ (X = D, T) basis set.	Nitrogen	79-81	tryptase pseudogene 1	Homo sapiens	115-118
23470981-5	2013	In this study we have linked each of the glycosylated and non-N-glycosylated soluble porcine CTLA-4 proteins to the truncated diphtheria toxin DT390 through genetic engineering yielding three versions of the porcine CTLA-4 fusion toxins: 1) monovalent glycosylated soluble porcine CTLA-4 fusion toxin; 2) monovalent non-N-glycosylated soluble porcine CTLA-4 fusion toxin and 3) bivalent non-N-glycosylated soluble porcine CTLA-4 fusion toxin.	Nitrogen	62-63	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	93-99
23470981-5	2013	In this study we have linked each of the glycosylated and non-N-glycosylated soluble porcine CTLA-4 proteins to the truncated diphtheria toxin DT390 through genetic engineering yielding three versions of the porcine CTLA-4 fusion toxins: 1) monovalent glycosylated soluble porcine CTLA-4 fusion toxin; 2) monovalent non-N-glycosylated soluble porcine CTLA-4 fusion toxin and 3) bivalent non-N-glycosylated soluble porcine CTLA-4 fusion toxin.	Nitrogen	320-321	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	93-99
23470981-5	2013	In this study we have linked each of the glycosylated and non-N-glycosylated soluble porcine CTLA-4 proteins to the truncated diphtheria toxin DT390 through genetic engineering yielding three versions of the porcine CTLA-4 fusion toxins: 1) monovalent glycosylated soluble porcine CTLA-4 fusion toxin; 2) monovalent non-N-glycosylated soluble porcine CTLA-4 fusion toxin and 3) bivalent non-N-glycosylated soluble porcine CTLA-4 fusion toxin.	Nitrogen	320-321	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	93-99
23470981-6	2013	Protein synthesis inhibition analysis demonstrated that while all three fusion toxins are capable of inhibiting protein synthesis in vitro, the non-N-glycosylated porcine CTLA-4 isoforms function most efficiently.	Nitrogen	148-149	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	171-177
23470981-7	2013	Binding analysis using flow cytometry of the porcine CTLA-4 fusion toxins to LCL13271 cells also demonstrated that the non-N-glycosylated porcine CTLA-4 isoforms bind to these cells with higher affinity compared to the glycosylated fusion toxin.	Nitrogen	123-124	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	146-152
23470981-8	2013	The monovalent non-N-glycosylated porcine CTLA-4 fusion toxin was tested in vivo.	Nitrogen	19-20	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	42-48
23470981-10	2013	All animals succumbed to tumors and those treated with the monovalent non-N-glycosylated porcine CTLA-4 fusion toxin survived longer based on a symptomatic scoring system compared to the untreated controls.	Nitrogen	74-75	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	97-103
25659750-3	2015	This could not be fully explained by the strong induction of GL3 in response to nitrogen depletion because the EGL3 transcripts were constitutively at a relatively high level and transcripts levels of the two genes were similar under nitrogen depletion.	Nitrogen	80-88	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	61-64
25659750-3	2015	This could not be fully explained by the strong induction of GL3 in response to nitrogen depletion because the EGL3 transcripts were constitutively at a relatively high level and transcripts levels of the two genes were similar under nitrogen depletion.	Nitrogen	234-242	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	61-64
25659750-4	2015	Here the GL3 and EGL3 proteins were characterized with respect to their affinities for PRODUCTION OF ANTHOCYANIN PIGMENT2 (PAP2), a R2R3-MYB which is induced by nitrogen depletion and is part of MBW complexes promoting anthocyanin synthesis.	Nitrogen	161-169	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	9-12
25659750-4	2015	Here the GL3 and EGL3 proteins were characterized with respect to their affinities for PRODUCTION OF ANTHOCYANIN PIGMENT2 (PAP2), a R2R3-MYB which is induced by nitrogen depletion and is part of MBW complexes promoting anthocyanin synthesis.	Nitrogen	161-169	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	17-21
25659750-9	2015	The present work underpins that GL3 is essential for anthocyanin accumulation under nitrogen depletion not only due to transcriptional activation, but also because of binding properties to proteins promoting or inhibiting the activity of the MBW complex.	Nitrogen	84-92	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	32-35
25426870-8	2015	CONCLUSION: Both AST-120 and LPD treatment lowered the Scr and blood urea nitrogen level as well as ameliorated the proteinuria and glomerular and tubulointerstitial damage of rats with early stage renal failure.	Nitrogen	74-82	acyl-CoA synthetase bubblegum family member 1	Rattus norvegicus	29-32
25598207-3	2015	In this work, the extraction complexes of AnO2(n+) (An = U, Np; n = 1, 2) with the traditional organophosphorus ligand HDEHP (di-(2-ethylhexyl)phosphoric acid) have been investigated using density functional theory together with scalar-relativistic effective core potentials (ECPs) for actinide elements.	Nitrogen	47-50	anoctamin 2	Homo sapiens	42-46
25232508-10	2014	Four weeks after HSC transplantation, Serum creatinine and urea nitrogen decreased 3.5 times and 2.1 times as well as HGF, IGF-1, VEGF and P53 using quantitative real-time PCR increased 4.3 times, 3.2, 2.4 and 4.2 times compared to ARF groups, respectively.	Nitrogen	64-72	fucosyltransferase 1 (H blood group)	Homo sapiens	17-20
25594316-0	2015	Mineralization of RDX-derived nitrogen to N2 via denitrification in coastal marine sediments.	Nitrogen	30-38	radixin	Homo sapiens	18-21
25594316-0	2015	Mineralization of RDX-derived nitrogen to N2 via denitrification in coastal marine sediments.	Nitrogen	42-44	radixin	Homo sapiens	18-21
25495042-4	2015	We first showed that TARP gamma-8 is an N-glycosylated protein, which contains two glycosylation sites, Asn53 and Asn56, and compared this with the glycosylation of TARP gamma-2 and the AMPA receptor auxiliary protein CNIH-2 (cornichon homologue 2).	Nitrogen	40-41	calcium voltage-gated channel auxiliary subunit gamma 8	Homo sapiens	21-33
23423259-5	2013	CRX-526 significantly reduced albuminuria and blood urea nitrogen without altering blood glucose and systolic blood pressure in diabetic mice.	Nitrogen	57-65	cone-rod homeobox	Mus musculus	0-3
23622502-13	2013	The importance of glutamine synthetase highlights a critical role for nitrogen metabolism in soil fitness.	Nitrogen	70-78	PFL01_RS27220	Pseudomonas fluorescens Pf0-1	18-38
25760531-6	2015	High benzydamine N-oxygenation activities of recombinant human FMO1 and FMO3 and human kidney microsomes were observed at pH 8.4, whereas N-demethylation by cytochrome P450 2D6 was faster at pH 7.4.	Nitrogen	17-18	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	72-76
23562325-6	2013	DPY-19 exhibits topological and sequential homology to the N-glycan oligosaccharyltransferase, highlighting an evolutionary link between N- and C-glycosylation.	Nitrogen	59-60	C-mannosyltransferase dpy-19	Caenorhabditis elegans	0-6
25760532-1	2015	Human flavin-containing monooxygenase 3 (FMO3) in the liver catalyzes a variety of oxygenations of nitrogen- and sulfur-containing medicines and xenobiotic substances.	Nitrogen	99-107	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	6-39
25047936-1	2014	Selective and nanomolar acetylcholinesterase inhibitors were obtained by connecting tri- and tetracyclic quinazolinones-previously described as moderately active and unselective cholinesterase (ChE) inhibitors-via a hydroxyl group in para position to an anilinic nitrogen with different amines linked via a three carbon atom spacer.	Nitrogen	263-271	butyrylcholinesterase	Homo sapiens	30-44
25760532-1	2015	Human flavin-containing monooxygenase 3 (FMO3) in the liver catalyzes a variety of oxygenations of nitrogen- and sulfur-containing medicines and xenobiotic substances.	Nitrogen	99-107	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	41-45
23361230-10	2013	They were also involved in the N-demethylation of the analogue methamphetamine and CYP2C19, CYP2D6, and CYP3A4 in its ring hydroxylation.	Nitrogen	31-32	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	83-90
25399018-9	2015	Real-time quantitative PCR analysis revealed that Tap46 overexpression induced transcriptional modulation of genes involved in nitrogen metabolism, ribosome biogenesis, and lignin biosynthesis.	Nitrogen	127-135	2A phosphatase associated protein of 46 kD	Arabidopsis thaliana	50-55
24786828-2	2014	In yeast, the Nitrogen permease regulators 2 and 3 (Npr2 and Npr3) mediate an essential response to amino-acid limitation upstream of TORC1.	Nitrogen	14-22	Target of rapamycin	Drosophila melanogaster	134-139
25877036-7	2015	And the damage of neuron increased versus I/R+NS group, brain infarction volume [(76 +- 6) vs (140 +- 10) mm(3)] and the expressions of astrocytic CX43 and GFAP were lower in I/R+Gap26 group [CX43: (0.43 +- 0.16) vs (2.15 +- 0.73); GFAP: (57 +- 6) vs (140 +- 9), P &lt; 0.05] and neuronal damage lessened.	Nitrogen	46-48	glial fibrillary acidic protein	Rattus norvegicus	232-236
25049824-14	2013	Nitrogen excretion (g/d) was lowered when dietary CP was reduced regardless of whether the values were determined through balance or calculated using ADG.	Nitrogen	0-8	ADG	Sus scrofa	150-153
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Nitrogen	69-70	mannose binding lectin 2	Homo sapiens	22-44
22528768-0	2013	(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF).	Nitrogen	22-23	cerebral dopamine neurotrophic factor	Homo sapiens	73-110
22528768-0	2013	(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF).	Nitrogen	22-23	cerebral dopamine neurotrophic factor	Homo sapiens	112-116
25705501-2	2015	The Cl atom and the N atom are syn.	Nitrogen	20-21	synemin	Homo sapiens	31-34
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Nitrogen	69-70	mannose binding lectin 2	Homo sapiens	46-49
26505688-0	2015	The Importance of the Microbial N Cycle in Soil for Crop Plant Nutrition.	Nitrogen	32-33	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	52-56
23370302-0	2013	Effects of the inhibitor of the gamma-aminobutyrate-transaminase, vinyl-gamma-aminobutyrate, on development and nitrogen metabolism in Brassica napus seedlings.	Nitrogen	112-120	gamma-aminobutyrate transaminase POP2, mitochondrial	Brassica napus	32-64
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Nitrogen	69-70	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	98-103
24825317-3	2014	Our results show that mannose binding lectin (MBL) that binds to the N-linked mannose residues on gp120, participates in intravesicular packaging of gp120 in neuronal subcellular organelles and also in subcellular trafficking of these vesicles in neuronal cells.	Nitrogen	69-70	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	149-154
25135935-6	2014	Cotranslational N-glycosylation by the STT3A isoform of the OST, which lacks MagT1, allows efficient modification of acceptor sites in cysteine-rich protein domains before disulfide bond formation.	Nitrogen	16-17	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	39-44
23432295-1	2013	We study spin relaxation and diffusion in an electron-spin ensemble of nitrogen impurities in diamond at low temperature (0.25-1.2 K) and polarizing magnetic field (80-300 mT).	Nitrogen	71-79	spindlin 1	Homo sapiens	9-13
23432295-1	2013	We study spin relaxation and diffusion in an electron-spin ensemble of nitrogen impurities in diamond at low temperature (0.25-1.2 K) and polarizing magnetic field (80-300 mT).	Nitrogen	71-79	spindlin 1	Homo sapiens	54-58
23088624-0	2013	N-Myristoylation is essential for protein phosphatases PPM1A and PPM1B to dephosphorylate their physiological substrates in cells.	Nitrogen	0-1	protein phosphatase, Mg2+/Mn2+ dependent 1A	Homo sapiens	55-60
23088624-3	2013	N-Myristoylation was also required for two other functions of PPM1A and PPM1B in cells.	Nitrogen	0-1	protein phosphatase, Mg2+/Mn2+ dependent 1A	Homo sapiens	62-67
23088624-6	2013	Taken together, the results of the present study suggest that N-myristoylation of PPM1A and PPM1B plays a key role in recognition of their physiological substrates in cells.	Nitrogen	62-63	protein phosphatase, Mg2+/Mn2+ dependent 1A	Homo sapiens	82-87
26421509-0	2015	The Genetics of Nitrogen Use Efficiency in Crop Plants.	Nitrogen	16-24	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	43-47
26421509-1	2015	In the past 50 years, the application of synthetic nitrogen (N) fertilizer to farmland resulted in a dramatic increase in crop yields but with considerable negative impacts on the environment.	Nitrogen	51-59	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	122-126
25362066-3	2015	Indeed, the action of AtzF provides metabolic access to two of the three nitrogens in each triazine ring.	Nitrogen	73-82	atzF	Pseudomonas sp. ADP	22-26
25996731-6	2015	The current investigation utilized a Nitrogen gas-induced pressure mechanism to disrupt elastin cross links that exist between annular lamellae.	Nitrogen	37-45	elastin	Homo sapiens	88-95
25470979-2	2015	DDR1 and DDR2 transfected in HEK293 cells were expressed mainly as 120 and 130 kDa forms, respectively, as they are sufficiently N-glycosylated.	Nitrogen	129-130	discoidin domain receptor tyrosine kinase 2	Homo sapiens	9-13
23147802-7	2013	Furthermore, dietary oat protein increased the levels of liver glycogen, enhanced the activities of lactic dehydrogenase and superoxide dismutase, and decreased the levels of blood urea nitrogen and malondialdehyde in serum.	Nitrogen	186-194	ornithine aminotransferase	Mus musculus	21-24
23340690-9	2013	Theoretical calculations further demonstrate that Cu(2+) ion binds to SS1 or SS2 in a slightly distorted tetragonal geometry with an S/N/2O environment and the minimum potential energy.	Nitrogen	135-136	butyrophilin like 2	Homo sapiens	77-80
24648901-7	2013	No difference was found in the T/N ratio of PD-L1/beta actin mRNA levels among factors inlcuding gender, age, smoking status and pathological subtypes.	Nitrogen	0-1	POTE ankyrin domain family member F	Homo sapiens	50-60
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	ornithine transcarbamylase	Homo sapiens	110-136
24648901-8	2013	The T/N ratio of PD-L1/beta actin mRNA levels was markedly higher in pathological T4 cases (15.811+-36.883) compared to T1 cases (3.492+-8.494, P=0.0235).	Nitrogen	6-7	POTE ankyrin domain family member F	Homo sapiens	23-33
23924466-11	2013	CONCLUSIONS: High Five insect cells derived recombinant human TPO ectodomain had N-glycosylation sites, which might have little effect on recognition by serum TPOAb.	Nitrogen	2-3	thyroid peroxidase	Homo sapiens	62-65
25556799-15	2015	We conclude that beta2-laminin is a key regulator in development of the NMJ, with its loss resulting in reduced transmitter release due to decreased calcium sensitivity stemming from a failure to switch from N- to P/Q-type VGCC-mediated synaptic transmission.	Nitrogen	72-73	hemoglobin, beta adult minor chain	Mus musculus	17-22
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	ornithine transcarbamylase	Homo sapiens	138-141
24733517-6	2015	A deletion in ARO8, which encodes an aromatic amino acid transaminase, was found to underlie the transcriptional upregulation of ARO10 during growth, with ammonium sulphate as the sole nitrogen source.	Nitrogen	185-193	bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	14-18
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	argininosuccinate synthase 1	Homo sapiens	144-170
24733517-8	2015	Moreover, deletion of ARO8 led to de novo production of phenylethanol during growth on a glucose synthetic medium with ammonium as the sole nitrogen source.	Nitrogen	140-148	bifunctional 2-aminoadipate transaminase/aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	22-26
23681536-2	2013	For instance, the involvement of plant PLD members has been shown or suggested in a wide variety of the cellular and physiological processes such as regulating stomatal opening and closure; signaling plant responses to drought, salt, and other abiotic and biotic stresses; organizing microtubule and actin cytoskeletal structures; promoting pollen tube growth; cycling phosphorus; signaling nitrogen availability; regulating N-acylethanolamine stress signaling; and remodeling membrane phospholipids in plant responses to phosphate deprivation and during and after freezing.	Nitrogen	391-399	phospholipase D alpha 1	Arabidopsis thaliana	39-42
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	argininosuccinate synthase 1	Homo sapiens	172-175
24841887-6	2014	Moreover, at a higher, toxicological concentration of the neuroleptic (100muM), the relative contribution of CYP1A2 to levomepromazine metabolism visibly increases (from 20% to 28% for 5-sufoxidation, and from 8% to 32% for N-demethylation), while the role of CYP3A4 significantly decreases (from 72% to 59% for 5-sulfoxidation, and from 78% to 47% for N-demethylation).	Nitrogen	224-225	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	109-115
23028104-8	2013	Serum levels of blood urea nitrogen and creatinine and urinary excretion levels of albumin and N-acetyl-beta-D-glucosaminidase were significantly elevated in diabetic MMP-2 KO mice when compared with wild-type diabetic littermates.	Nitrogen	27-35	matrix metallopeptidase 2	Mus musculus	167-172
25378396-0	2014	Klotho up-regulates renal calcium channel transient receptor potential vanilloid 5 (TRPV5) by intra- and extracellular N-glycosylation-dependent mechanisms.	Nitrogen	119-120	klotho	Homo sapiens	0-6
25415587-0	2014	Exploring the interaction of N/S compounds with a dicopper center: tyrosinase inhibition and model studies.	Nitrogen	29-30	tyrosinase	Homo sapiens	67-77
21837554-1	2013	Parallel acquisition NMR spectroscopy (PANSY) is used to detect simultaneously signals from up to four nuclear species, such as H-1, H-2, C-13, N-15, F-19 and P-31.	Nitrogen	21-22	relaxin 2	Homo sapiens	133-136
24841887-6	2014	Moreover, at a higher, toxicological concentration of the neuroleptic (100muM), the relative contribution of CYP1A2 to levomepromazine metabolism visibly increases (from 20% to 28% for 5-sufoxidation, and from 8% to 32% for N-demethylation), while the role of CYP3A4 significantly decreases (from 72% to 59% for 5-sulfoxidation, and from 78% to 47% for N-demethylation).	Nitrogen	353-354	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	109-115
21837554-1	2013	Parallel acquisition NMR spectroscopy (PANSY) is used to detect simultaneously signals from up to four nuclear species, such as H-1, H-2, C-13, N-15, F-19 and P-31.	Nitrogen	21-22	homeobox C13	Homo sapiens	138-142
25278359-5	2014	Whereas the Cu NPs acted as the catalyst for the reduction, CeO2 facilitated the incorporation of nitrogen from the pyridine source into the ACF/CNF surface.	Nitrogen	98-106	NPHS1 adhesion molecule, nephrin	Homo sapiens	145-148
24723502-8	2014	Deletion of TAT2 endorsed this strain with the highest nitrogen consumption capacity and the greatest fermentation activity at low temperature.	Nitrogen	55-63	aromatic amino acid transmembrane transporter TAT2	Saccharomyces cerevisiae S288C	12-16
25374123-0	2014	In-depth analysis of site-specific N-glycosylation in vitronectin from human plasma by tandem mass spectrometry with immunoprecipitation.	Nitrogen	35-36	vitronectin	Homo sapiens	54-65
25374123-8	2014	As a result, a total of 17 site-specific N-glycopeptides were completely identified in all of the three N-glycosylation sites of vitronectin in human plasma, including 12 N-glycopeptides first reported.	Nitrogen	41-42	vitronectin	Homo sapiens	129-140
25241292-5	2014	N-demethylation of the active metabolite MAA is diminished in carriers of the CYP2C19*2 allele and in NAT2-slow acetylators.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	78-85
25241292-5	2014	N-demethylation of the active metabolite MAA is diminished in carriers of the CYP2C19*2 allele and in NAT2-slow acetylators.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	102-106
23114595-5	2012	The mutation caused an alanine-to-serine substitution in the integrin alpha3 subunit, thereby introducing an N-glycosylation motif at amino acid position 349.	Nitrogen	109-110	integrin subunit alpha 3	Homo sapiens	61-76
23092368-7	2012	Regarding their dynamic behavior, low activation barriers were found by DFT calculations for the inversion of the nitrogen at the indolizidine framework, allowing rapid equilibration between the major configurations (ttc and ttt) in T3 and T4.	Nitrogen	114-122	solute carrier family 25 member 5	Homo sapiens	233-235
23187522-2	2012	Initial results confirm that using high energy nitrogen ion implantation to create EL-2 type trapping levels produces a photocarrier recombination time of a few picoseconds.	Nitrogen	47-55	spectrin alpha, erythrocytic 1	Homo sapiens	83-87
24828975-8	2014	The N-demethylation was catalyzed by CYP2B6, CYP2C19, CYP2D6, and CYP3A4, the aromatic hydroxylation by CYP2C19 and CYP2D6, and the aliphatic hydroxylation was catalyzed by CYP1A2, CYP2B6, CYP2C19, and CYP3A4.	Nitrogen	4-5	cytochrome P450, family 2, subfamily b, polypeptide 3	Rattus norvegicus	37-43
23136435-1	2012	Trans-soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes formed between the SNARE motifs of synaptobrevin II, SNAP-25, and syntaxin play an essential role in Ca(2+)-regulated exocytosis.	Nitrogen	14-15	vesicle-associated membrane protein 2	Mus musculus	136-152
25293377-0	2014	N-linked glycosylation of AtVSR1 is important for vacuolar protein sorting in Arabidopsis.	Nitrogen	0-1	vacuolar sorting receptor homolog 1	Arabidopsis thaliana	26-32
24895758-8	2014	Interestingly, CAT1 belongs to a specific small cluster of nitrogen-containing metabolite transporter genes that are rapidly up-regulated upon infection with Pseudomonas syringae and that may participate in the systemic response of plants to pathogen attack.	Nitrogen	59-67	catalase 1	Arabidopsis thaliana	15-19
25293377-6	2014	Hence, N-glycosylation of AtVSR1 plays a critical role in its function as a VSR in plants.	Nitrogen	7-8	vacuolar sorting receptor homolog 1	Arabidopsis thaliana	26-32
25240094-3	2014	Flexible alignment and docking studies of the inhibitors in the CYP24A1 enzyme active site confirmed that complete occupation of the vitamin D access tunnel is essential to inhibitory activity, allowing exposure to multiple hydrophobic binding interactions and optimal conformation for the interaction of the imidazole nitrogen lone pair and the active site haem.	Nitrogen	319-327	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	64-71
23240562-4	2012	Transport of Ca2+ in cells is under constant influence of active forms of oxygen and nitrogen.	Nitrogen	85-93	carbonic anhydrase 2	Homo sapiens	13-16
23240562-6	2012	The control of cardiac rhythm by active forms of oxygen and nitrogen represents a feedback mechanism by which mitochondria and NO-synthases support Ca2+ homeostasis in cells that can be temporarily disturbed under mechanical loads or hypoxia.	Nitrogen	60-68	carbonic anhydrase 2	Homo sapiens	148-151
24886084-11	2014	We have identified a role for fatty acid biosynthesis, and SACPD activity in particular, in the establishment and maintenance of symbiotic nitrogen fixation.	Nitrogen	139-147	stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic	Glycine max	59-64
22842044-4	2012	CD14(+)CD16(-) monocytes showed a higher production of reactive oxygen and nitrogen intermediates after stimulation with tumor cells, and more pronounced inhibition of tumor growth in vivo.	Nitrogen	75-83	Fc gamma receptor IIIa	Homo sapiens	7-11
25288789-3	2014	SMPDL3A protein expression in and secretion from primary macrophages are stimulated by cholesterol loading, liver X receptor ligands, and cyclic AMP, and N-glycosylated SMPDL3A protein is detectable in circulating blood.	Nitrogen	154-155	sphingomyelin phosphodiesterase acid like 3A	Homo sapiens	169-176
24719335-0	2014	N-glycosylation determines the abundance of the transient receptor potential channel TRPP2.	Nitrogen	0-1	polycystin 2, transient receptor potential cation channel	Mus musculus	85-90
25115772-8	2014	Diabetes-induced abnormal liver (aspartate aminotransferase and alanine aminotransferase) and kidney (blood urea nitrogen and uric acid) parameters were corrected in GLP-1-treated rats compared to controls.	Nitrogen	113-121	glucagon	Rattus norvegicus	166-171
22939867-3	2012	Meanwhile, more convincing results are observed in the fat-1 transgenic mice, which are exogenously inserted in a fat-1 gene from Caenorhabditis elegans, which can endogenously convert n-6 polyunsaturated fatty acids (n-6 PUFAs) to n-3 PUFAs.	Nitrogen	3-4	FAT atypical cadherin 1	Mus musculus	114-119
22956764-3	2012	Although it has been widely proposed that Pmm2 deficiency depletes M1P, a precursor of GDP-mannose, and consequently suppresses lipid-linked oligosaccharide (LLO) levels needed for N-glycosylation, these deficiencies have not been demonstrated in patients or any animal model.	Nitrogen	181-182	phosphomannomutase 2	Homo sapiens	42-46
24719335-3	2014	TRPP2 has been shown to be heavily N-glycosylated, but the glycosylation sites and the biological role of N-linked glycosylation have not been investigated.	Nitrogen	35-36	polycystin 2, transient receptor potential cation channel	Mus musculus	0-5
25330360-14	2014	Spin-spin coupling constants (1p)J(P-N) for (PF5, PHF4) complexes with nitrogen bases are negative with the strongest bases NC(-) and NCLi but positive for the remaining bases.	Nitrogen	71-79	PHD finger protein 21B	Homo sapiens	50-54
24738840-3	2014	We present here a new material, termed nitrogen-rich carbon aerogels (NRC aerogels,) with highly porous structure and nitrogen-rich surfaces, exhibiting highly efficient separation of specific substances such as oils and organic pollutants.	Nitrogen	39-47	nuclear receptor coactivator 6	Homo sapiens	70-73
25135642-10	2014	However, mutation of glycosylation site N-497 abrogates transport of ARSG to lysosomes in human fibrosarcoma cells, due to impaired mannose 6-phosphate modification.	Nitrogen	40-41	arylsulfatase G	Homo sapiens	69-73
22902581-4	2012	In the lowest energy form (E-AG) the O-C-CN and CN-N-Lp (Lp=lone electron pair of amine nitrogen atom) dihedral angles are predicted by the calculations to be -177.2  and 93.7 , respectively.	Nitrogen	88-96	potassium voltage-gated channel subfamily H member 1	Homo sapiens	27-31
22984264-0	2012	N-myristoylation and Ca2+ binding of calcineurin B homologous protein CHP3 are required to enhance Na+/H+ exchanger NHE1 half-life and activity at the plasma membrane.	Nitrogen	0-1	tescalcin	Homo sapiens	70-74
24738840-3	2014	We present here a new material, termed nitrogen-rich carbon aerogels (NRC aerogels,) with highly porous structure and nitrogen-rich surfaces, exhibiting highly efficient separation of specific substances such as oils and organic pollutants.	Nitrogen	118-126	nuclear receptor coactivator 6	Homo sapiens	70-73
25178915-6	2014	RESULTS: The mean MGMT promoter methylation for tumors with T/N ratios &gt;=1.6 was 28.0+-26.3, and that for tumors with T/N ratios &lt;1.6 was 0.68+-0.89.	Nitrogen	62-63	O-6-methylguanine-DNA methyltransferase	Homo sapiens	18-22
25178915-7	2014	The MGMT promoter methylation for tumors with T/N ratios &gt;=1.6 was significantly higher than that for tumors with T/N ratios &lt;1.6 (P&lt;0.05).	Nitrogen	48-49	O-6-methylguanine-DNA methyltransferase	Homo sapiens	4-8
25178915-7	2014	The MGMT promoter methylation for tumors with T/N ratios &gt;=1.6 was significantly higher than that for tumors with T/N ratios &lt;1.6 (P&lt;0.05).	Nitrogen	119-120	O-6-methylguanine-DNA methyltransferase	Homo sapiens	4-8
25144919-3	2014	Individual molecules adopt the syn conformation in the crystal, with the oxygen atom of the aldehyde substituent directed toward the same side of the ring nitrogen atom.	Nitrogen	155-163	synemin	Homo sapiens	31-34
25179102-0	2014	Enhancing electrocatalytic performance of Sb-doped SnO 2 electrode by compositing nitrogen-doped graphene nanosheets.	Nitrogen	82-90	strawberry notch homolog 2	Homo sapiens	51-54
22985516-7	2012	BMP-7 binding was seen as puncta in the SVZ at the location of fractones, the particulate specialized extracellular matrix of the SVZ, which have been identified primarily by N-sulfated heparan sulfate immunoreactivity (NS-HS+).	Nitrogen	175-176	bone morphogenetic protein 7	Mus musculus	0-5
22898812-8	2012	The Ser340/341A mutation did not alter the overall fold of N-ATP7B, but significantly decreased interactions with the nucleotide-binding domain, mimicking consequences of copper binding to N-ATP7B.	Nitrogen	189-190	ATPase copper transporting beta	Homo sapiens	191-196
24936167-12	2014	Our antibodies detected different glycosylated SUR2 receptor species after the PNGase F treatment, suggesting that SUR2 could be modified by N-glycosylation.	Nitrogen	80-81	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	Mus musculus	47-51
23066359-11	2012	Good CPAP adherence groups had significantly lower %N2 and greater %REM on the titration NPSG.	Nitrogen	52-54	centromere protein J	Homo sapiens	5-9
25119431-2	2014	Syn adducts emerge with regard to the vicinal nitrogen and oxygen heteroatom substituents.	Nitrogen	46-54	synemin	Homo sapiens	0-3
24936167-12	2014	Our antibodies detected different glycosylated SUR2 receptor species after the PNGase F treatment, suggesting that SUR2 could be modified by N-glycosylation.	Nitrogen	80-81	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	Mus musculus	115-119
24936167-17	2014	Increasing SUR2 expression by N-glycosylation mediated by estrogen may be effective to enhance KATP channel subunit expression in I-R.	Nitrogen	30-31	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	Mus musculus	11-15
25518667-11	2014	Thus, the contributions of the ABR and the MBR were intensified, guaranteeing the efficiency of nitrogen and phosphorus removal in the system.	Nitrogen	96-104	translocator protein	Homo sapiens	43-46
22970883-2	2012	After protection of the cis-2,3-bis(hydroxymethyl)aziridine with a Boc group, desymmetrization provided a chiral aziridine, which was a key intermediate to install the required stereogenic center containing a nitrogen atom.	Nitrogen	209-217	suppressor of cytokine signaling 2	Homo sapiens	24-29
24977290-0	2014	Identification of N-linked glycosylation and putative  O-fucosylation, C-mannosylation sites in plasma derived  ADAMTS13.	Nitrogen	18-19	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	112-120
22885760-7	2012	However, interrelations with environmental parameters among subgroup terminal restriction fragments (T-RFs) differed significantly, e.g., different Gp1 T-RFs correlated positively or negatively with nitrogen content.	Nitrogen	199-207	GTP binding protein 1	Homo sapiens	148-151
24449394-5	2014	Liquid urea applied with GA3 also reduced total N and nitrate-N concentration in herbage, relative to liquid urea applied alone.	Nitrogen	48-49	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	25-28
24970053-7	2014	Therefore, we established beta3GnT8-knockdown cell lines derived from the LN229 and SGC-7901 cell lines to examine the level of polylactosamine and CD147 N-glycosylation.	Nitrogen	75-76	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	Homo sapiens	26-35
24977290-4	2014	OBJECTIVES: Here we investigated the presence of putative O-fucosylation, C-mannosylation and N-linked glycosylation sites on plasma derived ADAMTS13.	Nitrogen	94-95	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	141-149
24970053-10	2014	In conclusion, we found that beta3GnT8 regulated the level of N-glycans on CD147 and that N-glycosylation of CD147 has an important effect on MMP-2 expression.	Nitrogen	62-63	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	Homo sapiens	29-38
24977290-6	2014	Nine of the 10 predicted N-linked glycosylation sites were identified in or near the metalloproteinase,spacer, thrombospondin type 1 repeat (TSR1) and the CUB domain of plasma ADAMTS13.	Nitrogen	0-1	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	176-184
22865878-0	2012	Eukaryotic N-glycosylation occurs via the membrane-anchored C-terminal domain of the Stt3p subunit of oligosaccharyltransferase.	Nitrogen	11-12	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	85-90
24673332-2	2014	Herein, the factors governing selective Rh2(esp)2-catalyzed C-H amination of isoamylbenzene derivatives are investigated, where modification to both the nitrogen source, a sulfamate ester, and substrate are shown to impact isomeric product ratios.	Nitrogen	153-161	Rh associated glycoprotein	Homo sapiens	40-43
22441658-6	2012	(2) The level of ICAM-1 and TIMP-2 of serum in CO(2) and N(2) group after 2 weeks of pneumoperitoneum were higher than air group.	Nitrogen	57-61	intercellular adhesion molecule 1	Rattus norvegicus	17-23
22441658-7	2012	(3) The expression of CD44v6, ICAM-1, MMP-2 and VEGF of tissue in CO(2) and N(2) group after 1, 2 and 4 weeks of pneumoperitoneum were lower than air group, TIMP-2 and ENS were higher than air group.	Nitrogen	76-80	intercellular adhesion molecule 1	Rattus norvegicus	30-36
24618259-6	2014	The N-glycosylation profile of monomeric rBChE secreted to the apoplast largely resembles the plasma-derived orthologue.	Nitrogen	4-5	butyrylcholinesterase	Rattus norvegicus	41-46
22860915-5	2012	N-Glycosylation and particularly the content of nonfucosylated glycans are crucial for affinity of mAb to FcgammaRIIIA, which plays the key role in the clearance of sensitized cells.	Nitrogen	0-1	Fc gamma receptor IIIa	Homo sapiens	106-118
24657054-5	2014	The SAR reported here is focused on the influence of various piperidine nitrogen aromatic substituents on the ratio of binding affinity and intrinsic activity at both the NOP and MOP receptors.	Nitrogen	72-80	opioid receptor mu 1	Homo sapiens	179-182
22736280-6	2012	Furthermore, we found that the regulated GnT-IVa converts the heterogeneous N-glycosylated forms of CD147 in Hepa1-6 and Hca-F cells, and significantly changed the antennary oligosaccharide structures on CD147.	Nitrogen	76-77	basigin	Mus musculus	100-105
24983310-6	2014	RESULTS: CD47mAb perfusion of donor kidneys resulted in marked improvement in posttransplant survival, lower levels of serum creatinine, blood urea nitrogen, phosphorus and magnesium, and less histological evidence of injury.	Nitrogen	148-156	CD47 molecule	Homo sapiens	9-13
22736280-6	2012	Furthermore, we found that the regulated GnT-IVa converts the heterogeneous N-glycosylated forms of CD147 in Hepa1-6 and Hca-F cells, and significantly changed the antennary oligosaccharide structures on CD147.	Nitrogen	76-77	basigin	Mus musculus	204-209
24575873-6	2014	Besides, the coordination interaction between the lone-pair electrons on the N atoms of the amino (-NH2) group and the Al atoms may prohibit interaction between Al and the thiophene rings of P3HT, contributing to the efficiency enhancement of the CBL-incorporated devices as well.	Nitrogen	77-78	Cbl proto-oncogene	Homo sapiens	247-250
22779681-5	2012	The results show that SDF-1alpha analogues with a modified N-methylated main chain at position 2, 3, or 5 retain significant CXCR4 binding and yet completely lose signaling activities.	Nitrogen	59-60	C-X-C motif chemokine receptor 4	Homo sapiens	125-130
22634084-0	2012	Analysis of N-glycosylation in maize cytokinin oxidase/dehydrogenase 1 using a manual microgradient chromatographic separation coupled offline to MALDI-TOF/TOF mass spectrometry.	Nitrogen	12-13	cytokinin dehydrogenase 1	Zea mays	37-68
22467853-0	2012	The oligosaccharyltransferase subunits OST48, DAD1 and KCP2 function as ubiquitous and selective modulators of mammalian N-glycosylation.	Nitrogen	121-122	defender against cell death 1	Homo sapiens	46-50
22467853-7	2012	Thus, OST48 and DAD1 are global modulators of OST stability and hence N-glycosylation.	Nitrogen	70-71	defender against cell death 1	Homo sapiens	16-20
25099331-2	2014	The effect of polymer composition on the properties of the carbon dots was investigated by TEM, IR, XPS, elemental analysis and fluorescence analysis, with carbon dots synthesised from nitrogen-containing polymers showing the highest fluorescence.	Nitrogen	185-193	MFT2	Homo sapiens	91-94
24915880-1	2014	Part 4: influence of N-substitution on P-glycoprotein substrate activity of noroxymorphone analogues.	Nitrogen	21-22	ATP-binding cassette, subfamily B (MDR/TAP), member 1B	Rattus norvegicus	39-53
24866178-4	2014	Moreover, ectopic expression of fat-1, a desaturase, catalyzed the conversion of n-6 to n-3 PUFAs and produced n-3 PUFAs endogenously, also suppressed endometrial tumor cell growth and migration, and potentiated apoptosis in endometrial cancer cell lines.	Nitrogen	27-28	FAT atypical cadherin 1	Mus musculus	32-51
25000295-11	2014	Further study demonstrated that folate profiling and N metabolism were perturbed in atdfb-3 etiolated seedlings.	Nitrogen	53-54	DHFS-FPGS homolog B	Arabidopsis thaliana	84-89
22607976-5	2012	Inhibition of posttranslational N-glycosylation increases detergent-insoluble TTR aggregates and decreases cell proliferation of mutant TTR-expressing cells.	Nitrogen	32-33	transthyretin	Homo sapiens	78-81
24616224-2	2014	A selective autophagic pathway for 60S ribosomal subunits elicited by nitrogen starvation in yeast-ribophagy-was recently described and requires the Ubp3-Bre5 deubiquitylating enzyme.	Nitrogen	70-78	Bre5p	Saccharomyces cerevisiae S288C	154-158
22607976-5	2012	Inhibition of posttranslational N-glycosylation increases detergent-insoluble TTR aggregates and decreases cell proliferation of mutant TTR-expressing cells.	Nitrogen	32-33	transthyretin	Homo sapiens	136-139
25000295-13	2014	Taken together, these results indicate that AtDFB is required for seed reserves, hypocotyl elongation and N metabolism in darkness, providing novel insights into potential associations of folate metabolism with seed reserve accumulation, N metabolism and hypocotyl development in Arabidopsis.	Nitrogen	106-107	DHFS-FPGS homolog B	Arabidopsis thaliana	44-49
24413606-0	2014	Biogeography of the sediment bacterial community responds to a nitrogen pollution gradient in the East China Sea.	Nitrogen	63-71	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	109-112
24751973-4	2014	Pre-treatment with CS-P significantly attenuated the deleterious renal functions caused by LPS, i.e., elevated blood urea nitrogen and creatinine as well as urine protein.	Nitrogen	122-130	DnaJ heat shock protein family (Hsp40) member C5	Rattus norvegicus	19-23
24742667-2	2014	Here, we review studies describing how dysregulation of the N-glycosylation-regulating gene, DPAGT1, drives oral cancer.	Nitrogen	60-61	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	93-99
22753898-6	2012	In their view, PSEN1 mediates the N-glycosylation of V0a1 in the endoplasmic reticulum (ER); consequently, PSEN deficiency prevents V0a1 glycosylation, compromising the delivery of unglycosylated V0a1 to lysosomes, ultimately impairing V-ATPase function and lysosomal acidification.	Nitrogen	18-19	Vacuolar H[+] ATPase 100kD subunit 1	Drosophila melanogaster	132-136
25053991-9	2014	These PTM are supported through in silico analysis, where several modifications such as N-glycosylation, N-Glycation, Phosphorylation and O-linked beta-N-acetylglucosamine, may occur in STEAP1 protein.	Nitrogen	88-89	STEAP family member 1	Homo sapiens	186-192
22719553-3	2012	In each mol-ecule, there is a twist in the link between the approximately syn carbonyl and amine groups [the N-C-C-O torsion angles range from 19.73 (19) to -21.2 (2) ].	Nitrogen	109-110	synemin	Homo sapiens	74-77
22493305-2	2012	Here, we show that this RNA, termed nitrogen assimilation leader A (NalA), represents the leader RNA of the nirBD-PA1779-cobA operon, and that nalA transcription is sigma(54)- and NtrC-dependent.	Nitrogen	36-44	assimilatory nitrate reductase	Pseudomonas aeruginosa PAO1	114-120
24742667-4	2014	DPAGT1 controls N-glycosylation of E-cadherin, the major epithelial cell-cell adhesion receptor and a tumor suppressor, thereby affecting intercellular adhesion and cytoskeletal dynamics.	Nitrogen	16-17	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	0-6
25016856-6	2014	GO and Pathway analysis of 27 genes around the 39 SNPs indicated that these genes mainly participate in the regulating of cell proliferation, regulation of nitrogen compound metabolic process and G-protein coupled receptor protein signaling pathway and so on.	Nitrogen	156-164	C-X-C motif chemokine receptor 6	Homo sapiens	196-222
25147610-2	2014	Reducing structure complexity of the N-alkyl substituent led to the discovery of 23, a potent and simplified inhibitor of MDM2.	Nitrogen	37-38	MDM2 proto-oncogene	Rattus norvegicus	122-126
24653997-1	2014	The dynamics of actinyl ions (AnO2(n+)) in aqueous solutions is important not only for the design of advanced separation processes but also for understanding the fate of actinides in the environment.	Nitrogen	35-38	anoctamin 2	Homo sapiens	30-34
22764522-9	2012	Thus these results show that the N-linked glycosylation in the prME and NS1 gene were correlated with the immunity, one glycan absent would enhance the immunity but both two loss would impair it.	Nitrogen	33-34	influenza virus NS1A binding protein	Homo sapiens	72-75
22351761-0	2012	Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1.	Nitrogen	21-22	glypican 1	Homo sapiens	42-52
24574032-3	2014	Herein, boron/nitrogen co-doped graphene (BCN-graphene) is directly synthesized from the reaction of CCl4 , BBr3 , and N2 in the presence of potassium.	Nitrogen	14-22	C-C motif chemokine ligand 4	Homo sapiens	101-105
22351761-0	2012	Crystal structure of N-glycosylated human glypican-1 core protein: structure of two loops evolutionarily conserved in vertebrate glypican-1.	Nitrogen	21-22	glypican 1	Homo sapiens	129-139
22351761-6	2012	We expressed and crystallized N-glycosylated human glypican-1 lacking HS and N-glycosylated glypican-1 lacking the HS attachment domain.	Nitrogen	30-31	glypican 1	Homo sapiens	51-61
22351761-6	2012	We expressed and crystallized N-glycosylated human glypican-1 lacking HS and N-glycosylated glypican-1 lacking the HS attachment domain.	Nitrogen	77-78	glypican 1	Homo sapiens	92-102
22351761-9	2012	The crystal structure of N-glycosylated human glypican-1 core protein at 2.5 A, the first crystal structure of a vertebrate glypican, reveals the complete disulfide bond arrangement of the conserved Cys residues, and it also extends the structural knowledge of glypicans for one alpha-helix and two long loops.	Nitrogen	25-26	glypican 1	Homo sapiens	46-56
24628331-4	2014	A total of 14 unique N-linked glycans corresponding to 27 unique N-linked glycopeptides were characterized at three N-linked sites (Asn-86, -169, and -242) present in VTN.	Nitrogen	21-22	vitronectin	Homo sapiens	167-170
24816101-6	2014	However, a highly conserved lysine in O-sulfatases is replaced in SGSH by an arginine (Arg282) that is positioned to bind the N-linked sulfate substrate.	Nitrogen	126-127	N-sulfoglucosamine sulfohydrolase	Homo sapiens	66-70
24451387-0	2014	Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels.	Nitrogen	0-1	hyperpolarization activated cyclic nucleotide gated potassium channel 1	Homo sapiens	71-130
24451387-7	2014	Regulation may further include N-glycosylation of HCN1 channels, which is significantly enhanced by TRIP8b(1a-4), but may be reduced by Nedd4-2.	Nitrogen	31-32	hyperpolarization activated cyclic nucleotide gated potassium channel 1	Homo sapiens	50-54
24451387-7	2014	Regulation may further include N-glycosylation of HCN1 channels, which is significantly enhanced by TRIP8b(1a-4), but may be reduced by Nedd4-2.	Nitrogen	31-32	peroxisomal biogenesis factor 5 like	Homo sapiens	100-106
22383530-0	2012	Calcium-myristoyl Tug is a new mechanism for intramolecular tuning of calcium sensitivity and target enzyme interaction for guanylyl cyclase-activating protein 1: dynamic connection between N-fatty acyl group and EF-hand controls calcium sensitivity.	Nitrogen	190-191	ASPSCR1 tether for SLC2A4, UBX domain containing	Homo sapiens	18-21
22337603-3	2012	Both the desolvated frameworks display effective gas sorption capacities of N(2) and H(2) with Langmuir surface areas of 546 and 917 m(2) g(-1) for 1 and 2, respectively.	Nitrogen	76-80	proline rich protein BstNI subfamily 3	Homo sapiens	138-155
24451387-7	2014	Regulation may further include N-glycosylation of HCN1 channels, which is significantly enhanced by TRIP8b(1a-4), but may be reduced by Nedd4-2.	Nitrogen	31-32	NEDD4 like E3 ubiquitin protein ligase	Homo sapiens	136-143
24410629-0	2014	Theoretical studies of the mechanism of N-hydroxylation of primary aromatic amines by cytochrome P450 1A2: radicaloid or anionic?	Nitrogen	40-41	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	86-105
24554659-0	2014	Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.	Nitrogen	20-21	envelope protein	Simian immunodeficiency virus	85-106
24554659-2	2014	Here, we identify a highly conserved N-linked glycosylation site (N173 in SIV, corresponding to N160 in HIV) in the V2 region of the SIV envelope glycoprotein (Env) as a novel determinant of macrophage tropism and characterize mechanisms underlying this phenotype.	Nitrogen	37-38	envelope protein	Simian immunodeficiency virus	137-158
22589960-1	2012	The asymmetric unit of the title compound, C(23)H(23)N(3)O(2), contains two mol-ecules in both of which, one amide N atom is in a syn position with respect to the pyridine N atom, while the other amide N atom is in an anti position (the syn--anti conformation).	Nitrogen	53-54	synemin	Homo sapiens	130-133
22589960-1	2012	The asymmetric unit of the title compound, C(23)H(23)N(3)O(2), contains two mol-ecules in both of which, one amide N atom is in a syn position with respect to the pyridine N atom, while the other amide N atom is in an anti position (the syn--anti conformation).	Nitrogen	115-116	synemin	Homo sapiens	130-133
24554659-2	2014	Here, we identify a highly conserved N-linked glycosylation site (N173 in SIV, corresponding to N160 in HIV) in the V2 region of the SIV envelope glycoprotein (Env) as a novel determinant of macrophage tropism and characterize mechanisms underlying this phenotype.	Nitrogen	37-38	envelope protein	Simian immunodeficiency virus	160-163
24410629-2	2014	The major event of the mechanism of their mutagenicity is N-hydroxylation by P450 enzymes, primarily P450 1A2 (CYP1A2), which leads to the formation of nitrenium ions that covalently modify nucleobases of DNA.	Nitrogen	58-59	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	111-117
22589960-1	2012	The asymmetric unit of the title compound, C(23)H(23)N(3)O(2), contains two mol-ecules in both of which, one amide N atom is in a syn position with respect to the pyridine N atom, while the other amide N atom is in an anti position (the syn--anti conformation).	Nitrogen	115-116	synemin	Homo sapiens	130-133
24410629-3	2014	Energy profiles of the NH bond activation steps of two possible mechanisms of N-hydroxylation of a number of aromatic amines by CYP1A2, radicaloid and anionic, are studied by dispersion-corrected DFT calculations.	Nitrogen	23-24	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	128-134
24449365-2	2014	The impact of dietary n-3 PUFA supplementation on physiological and biochemical processes involved in reproduction is likely to be associated with significant alterations in gene expression in key reproductive tissues which is in turn regulated by transcription factors.	Nitrogen	22-23	PUFA	Bos taurus	26-30
24410629-12	2014	Taken together, results suggest that the N-hydroxylation of aromatic amines in CYP1A2 undergoes the anionic mechanism.	Nitrogen	41-42	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	79-85
24449365-8	2014	Gene functions which showed a significant response to n-3 PUFA supplementation included tissue development, immune function and reproductive function.	Nitrogen	2-3	PUFA	Bos taurus	58-62
22401851-6	2012	It has recently yielded an N-methylated macrocyclic peptide having high affinity (Kd=0.60 nM) for its target protein, E6AP.	Nitrogen	27-28	ubiquitin protein ligase E3A	Homo sapiens	118-122
24600221-8	2014	The rapid decrease of blood creatinine, urine creatinine, and blood urea nitrogen suggested that the recovery of renal functions compromised by hyperglycemia could also be attributed to MCP-1.	Nitrogen	73-81	C-C motif chemokine ligand 2	Homo sapiens	186-191
22364147-3	2012	The pyrazine rings are seen to perform a 4-fold jump motion about the coordinating nitrogen axis in the high-spin state.	Nitrogen	83-91	spindlin 1	Homo sapiens	109-113
24460551-0	2014	Auxin biosynthetic gene TAR2 is involved in low nitrogen-mediated reprogramming of root architecture in Arabidopsis.	Nitrogen	48-56	tryptophan aminotransferase related 2	Arabidopsis thaliana	24-28
24460551-3	2014	Here, we show that low nitrogen-induced Arabidopsis LR growth depends on the function of the auxin biosynthesis gene TAR2 (tryptophan aminotransferase related 2).	Nitrogen	23-31	tryptophan aminotransferase related 2	Arabidopsis thaliana	117-121
24296531-1	2014	MP2/aug-cc-pVTZ calculations were carried out on complexes of ZH4, ZFH3 and ZF4 (Z = C, Si and Ge) molecules with HCN, LiCN and Cl(-) species acting as Lewis bases through nitrogen centre or chlorine ion.	Nitrogen	172-180	zinc finger homeobox 3	Homo sapiens	67-71
24460551-3	2014	Here, we show that low nitrogen-induced Arabidopsis LR growth depends on the function of the auxin biosynthesis gene TAR2 (tryptophan aminotransferase related 2).	Nitrogen	23-31	tryptophan aminotransferase related 2	Arabidopsis thaliana	123-160
24460551-4	2014	TAR2 was expressed in the pericycle and the vasculature of the mature root zone near the root tip, and was induced under low nitrogen conditions.	Nitrogen	125-133	tryptophan aminotransferase related 2	Arabidopsis thaliana	0-4
24460551-6	2014	Conversely, these low nitrogen-mediated auxin accumulation and root growth responses were impaired in the tar2-c null mutant.	Nitrogen	22-30	tryptophan aminotransferase related 2	Arabidopsis thaliana	106-110
24460551-7	2014	Overexpression of TAR2 increased LR numbers under both high and low nitrogen conditions.	Nitrogen	68-76	tryptophan aminotransferase related 2	Arabidopsis thaliana	18-22
24460551-8	2014	Our results suggested that TAR2 is required for reprogramming root architecture in response to low nitrogen conditions.	Nitrogen	99-107	tryptophan aminotransferase related 2	Arabidopsis thaliana	27-31
24460551-9	2014	This finding suggests a new strategy for improving nitrogen use efficiency through the engineering of TAR2 expression in roots.	Nitrogen	51-59	tryptophan aminotransferase related 2	Arabidopsis thaliana	102-106
24667701-2	2014	The results showed that the median total N concentrations of still surface water were significantly higher in the agro- (1.5 mg   L(-1)) and oasis agro- ecosystems (1.8 mg   L(-1)) than in the forest ecosystems (1.0 mg   L(-1)).	Nitrogen	41-42	cAMP responsive element binding protein 3 like 1	Homo sapiens	141-146
24667701-3	2014	This was also the case for flowing surface water, with total N concentrations of 2.4 mg   L(-1), 1.8 mg   L(-1) and 0.5 mg   L(-1) for the agro-, oasis agro- and forest ecosystems, respectively.	Nitrogen	61-62	cAMP responsive element binding protein 3 like 1	Homo sapiens	146-151
22324784-5	2012	X-ray crystallography of the syn isomer of complex 2 demonstrated that it has a distorted trigonal bipyramidal geometry with the nitrido group and the two sulfur atoms defining the equatorial plane, the phosphorus atom of the monophosphine and the protonated amine nitrogen of the tridentate ligand spanning the two reciprocal trans positions along the axis perpendicular to the trigonal plane.	Nitrogen	265-273	synemin	Homo sapiens	29-32
22114075-10	2012	This normalization of tumor vasculature functions under n-3 PUFA diet indicates that such a supplementation, by improving drug delivery in mammary tumors, could be a complementary clinical strategy to decrease anticancer drug resistance.	Nitrogen	5-6	pumilio RNA binding family member 3	Homo sapiens	60-64
20938793-7	2012	The results showed a moderate enhancement of OPG gene expression whereas RANKL gene expression was strongly increased by nitrogen-containing bisphosphonates reaching a maximum after 14 days at high concentrations of 5 x 10(-5) M. Lower concentrations did not enhance the RANKL and OPG expression considerably.	Nitrogen	121-129	TNF superfamily member 11	Homo sapiens	73-78
20938793-7	2012	The results showed a moderate enhancement of OPG gene expression whereas RANKL gene expression was strongly increased by nitrogen-containing bisphosphonates reaching a maximum after 14 days at high concentrations of 5 x 10(-5) M. Lower concentrations did not enhance the RANKL and OPG expression considerably.	Nitrogen	121-129	TNF superfamily member 11	Homo sapiens	271-276
20938793-8	2012	The non-nitrogen-containing bisphosphonate clodronate, however, effected OPG and RANKL gene expression much less, even at higher concentrations of 5 x 10(-3) M. The above-mentioned data suggest an enhanced RANKL/OPG gene expression after stimulation by bisphosphonates.	Nitrogen	8-16	TNF superfamily member 11	Homo sapiens	81-86
20938793-8	2012	The non-nitrogen-containing bisphosphonate clodronate, however, effected OPG and RANKL gene expression much less, even at higher concentrations of 5 x 10(-3) M. The above-mentioned data suggest an enhanced RANKL/OPG gene expression after stimulation by bisphosphonates.	Nitrogen	8-16	TNF superfamily member 11	Homo sapiens	206-211
24667701-5	2014	Nitrogen pollution in agro- ecosystems is mainly due to fertilizer applications, while the combination of fertilizer and irrigation exacerbates nitrogen pollution in oasis agro- ecosystems.	Nitrogen	144-152	cAMP responsive element binding protein 3 like 1	Homo sapiens	166-171
24296531-1	2014	MP2/aug-cc-pVTZ calculations were carried out on complexes of ZH4, ZFH3 and ZF4 (Z = C, Si and Ge) molecules with HCN, LiCN and Cl(-) species acting as Lewis bases through nitrogen centre or chlorine ion.	Nitrogen	172-180	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	114-117
24605289-5	2014	As revealed by electron microscopy studies (SEM, TEM), the individual N-CNTs (half as thick as MWCNTs) grown under the optimal conditions were characterized by a superior straightness of the outer walls, which translated into a high alignment of dense nanotube arrays, i.e., 5 x 10(8) nanotubes per mm(2) (100 times more than for MWCNTs grown in the absence of nitrogen precursor).	Nitrogen	70-71	MFT2	Homo sapiens	49-52
24449851-4	2014	To demonstrate the approach in practice, nitrogen cycling in the Arabian Sea oxygen minimum zone (OMZ) was modeled to examine key questions about cryptic sulfur cycling and dinitrogen production pathways in OMZs.	Nitrogen	41-49	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	73-76
24584735-5	2014	Pulse chase and mutational analysis indicated that HRD1 inhibits STT3B-dependent post-translational N-glycosylation of ABCG8.	Nitrogen	100-101	ATP binding cassette subfamily G member 8	Homo sapiens	119-124
22124158-5	2012	In nitrogen-starved cells, PHD1 expression is upregulated and the Phd1 protein becomes stabilized, which causes its accumulation during differentiation.	Nitrogen	3-11	Phd1p	Saccharomyces cerevisiae S288C	27-31
22124158-5	2012	In nitrogen-starved cells, PHD1 expression is upregulated and the Phd1 protein becomes stabilized, which causes its accumulation during differentiation.	Nitrogen	3-11	Phd1p	Saccharomyces cerevisiae S288C	66-70
24449851-5	2014	Simulations support previous assertions that denitrification dominates over anammox in the central Arabian Sea, which has important implications for the loss of fixed nitrogen from the oceans.	Nitrogen	167-175	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	107-110
22568215-5	2012	The skin lesion area was reduced remarkably after 3 times of liquid nitrogen freezing combined with ALA-PDT, 16-140 (median 38) mm2 for the first time, 6-63 (median 13) mm2 for the second, and 0-10 (median 3) mm2 for the third, with statistically significant differences (P &lt; 0.01).	Nitrogen	68-76	PNMA family member 2	Homo sapiens	128-131
24490900-0	2014	Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.	Nitrogen	0-8	tumor necrosis factor (ligand) superfamily, member 11	Mus musculus	44-49
22113586-1	2012	An efficient synthetic method for stereoselective construction of asymmetric quaternary carbon stereocenters, bearing nitrogen in the form of Boc-protected allyl amines, has been developed.	Nitrogen	118-126	BOC cell adhesion associated, oncogene regulated	Homo sapiens	142-145
24425764-1	2014	The oligopeptide transporter peptide cotransporter-1 Slc15a1 (PEPT1) plays a major role in the regulation of nitrogen supply, since it is responsible for 70% of the dietary nitrogen absorption.	Nitrogen	109-117	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	62-67
24425764-1	2014	The oligopeptide transporter peptide cotransporter-1 Slc15a1 (PEPT1) plays a major role in the regulation of nitrogen supply, since it is responsible for 70% of the dietary nitrogen absorption.	Nitrogen	173-181	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	62-67
24425764-2	2014	Previous studies demonstrated that PEPT1 expression and function in jejunum are reduced in diabetes and obesity, suggesting a nitrogen malabsorption from the diet.	Nitrogen	126-134	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	35-40
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	98-104	T cell receptor alpha locus	Homo sapiens	123-126
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	98-104	T cell receptor alpha locus	Homo sapiens	123-126
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	102-104	T cell receptor alpha locus	Homo sapiens	95-98
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	102-104	T cell receptor alpha locus	Homo sapiens	123-126
24429940-2	2014	Two types of structural isomers exhibiting different interaction motifs are identified for the TRA(+)-N2 dimer, namely the TRA(+)-N2(H) global minimum, in which N2 forms a linear hydrogen bond (H-bond) to the indolic NH group, and the less stable TRA(+)-N2(pi) local minima, in which N2 binds to the aromatic pi electron system of the indolic pyrrole ring.	Nitrogen	102-104	T cell receptor alpha locus	Homo sapiens	123-126
24456472-2	2014	Continued research investigation of the N-alkyl substituent of this series, focused in particular on a previously underutilized interaction in a shallow cleft on the MDM2 surface, led to the discovery of a one-carbon tethered sulfone which gave rise to substantial improvements in biochemical and cellular potency.	Nitrogen	40-41	MDM2 proto-oncogene	Homo sapiens	166-170
22197137-2	2012	The three sites impacting SAR are substitutions on the aryl group (R(1)), the piperidine nitrogen (R(2)), and the amide (R(3)).	Nitrogen	89-97	sarcosine dehydrogenase	Homo sapiens	26-29
22259551-1	2012	In the title compound, C(13)H(9)Cl(2)NO, the meta-Cl atom in the benzoyl ring is positioned anti to the C=O bond, while the ortho-Cl atom in the aniline ring is positioned syn to the N-H bond.	Nitrogen	37-38	synemin	Homo sapiens	172-175
24519134-11	2014	We conclude that N- and CDH fetuses showed primary pulmonary hypoplasia, with a decrease in VEGFR1 and VEGFR2 expression.	Nitrogen	17-18	kinase insert domain receptor	Rattus norvegicus	103-109
23231391-1	2012	Part II- discovery of MAO-B inhibitors based on nitrogen heterocycles and analogues.	Nitrogen	48-56	monoamine oxidase B	Homo sapiens	22-27
20858066-6	2012	Two novel compounds we report (MP1 and MP2) covalently link ibuprofen and ketoprofen directly to the amide nitrogen of n-acetyl-glucosamine (NAG); the other compound (MP3) covalently links ibuprofen to the amide nitrogen, using a short chain acetyl linker.	Nitrogen	212-220	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	Homo sapiens	31-34
32261282-6	2014	The complexes of Mag-VPCmns and nucleoside molecules with various N/P ratios were evaluated using gel electrophoresis, surface charge (zeta-potential) measurement, and particle size measurement.	Nitrogen	66-67	myelin associated glycoprotein	Homo sapiens	17-20
24194418-5	2014	The co-existence of two inorganic nitrogen sources (ammonia and nitrate) had certain impact on simazine dissipation by the strain SD1.	Nitrogen	34-42	CUP2Q35	Homo sapiens	130-133
24480069-7	2014	In parallel, in a disease with impaired GBM-maturation such as Alport syndrome, loss of integrin alpha2beta1 positively delays renal fibrosis: COL4A3(-/-)/ITGA2(-/-) double knockouts exhibited reduced proteinuria and urea nitrogen compared to COL4A3(-/-)/ITGA2(+/-) and COL4A3(-/-)/ITGA2(+/+) mice.	Nitrogen	222-230	collagen, type IV, alpha 3	Mus musculus	143-149
22952606-9	2012	CSF N-glycome analysis shows relevant quantitative changes associated with eIF2B related disorders.	Nitrogen	4-5	eukaryotic translation initiation factor 2B subunit delta	Homo sapiens	75-80
23917429-4	2014	N-glycosylation of molecules associated with glutamatergic neurotransmission is disrupted in schizophrenia, but it was unknown if these alterations are exclusive to the glutamatergic system or due to a more generalized deficit.In normal human cortex, we found evidence for N-glycosylation of the alpha1, beta1, and beta2 gamma-aminobutyric type A receptor (GABAAR) subunits using deglycosylation protein shift assays.	Nitrogen	0-1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	304-309
24478771-4	2014	Ultimately, myosin-dependent movement of the lytic granules toward the NK cell plasma membrane through F-actin channels, along with soluble N-ethylmaleimide-sensitive factor attachment protein receptor-dependent fusion, promotes the release of the lytic granule contents into the cleft between the NK cell and target cell resulting in target cell killing.	Nitrogen	71-72	myosin heavy chain 14	Homo sapiens	12-18
23917429-7	2014	Measures of altered N-glycosylation of the beta1 and beta2 subunits were confounded by an increased apparent molecular mass of all beta1 and beta2 subunit isoforms in schizophrenia.	Nitrogen	20-21	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	43-48
23917429-7	2014	Measures of altered N-glycosylation of the beta1 and beta2 subunits were confounded by an increased apparent molecular mass of all beta1 and beta2 subunit isoforms in schizophrenia.	Nitrogen	20-21	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	131-136
22720044-5	2012	This two-domain NADS arrangement enabling the utilization of glutamine as nitrogen donor is also present in various bacterial lineages.	Nitrogen	74-82	NAD synthetase 1	Homo sapiens	16-20
22720044-8	2012	However, a question about the actual in vivo nitrogen donor for single-domain members of the NADS family remained open: Is it glutamine hydrolyzed by a committed (but yet unknown) glutaminase subunit, as in most ATP-dependent amidotransferases, or free ammonia as in glutamine synthetase?	Nitrogen	45-53	NAD synthetase 1	Homo sapiens	93-97
24211109-5	2014	The mutant Kit is incompletely N-glycosylated, shows compromised receptor dimerization, and down-regulates Akt and extracellular signal-regulating kinase 1/2 signaling.	Nitrogen	31-32	KIT proto-oncogene receptor tyrosine kinase	Mus musculus	11-14
22192458-0	2011	Inhibition of N-linked glycosylation impairs ALK phosphorylation and disrupts pro-survival signaling in neuroblastoma cell lines.	Nitrogen	14-15	ALK receptor tyrosine kinase	Homo sapiens	45-48
24388610-3	2014	In Arabidopsis thaliana, GL3, a bHLH transcription factor, is important in the MBW complex regulating trichome formation as well as in the MBW complex induced by nitrogen depletion and promoting anthocyanin formation.	Nitrogen	162-170	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	25-28
24394775-0	2014	The carbon/nitrogen regulator ARABIDOPSIS TOXICOS EN LEVADURA31 controls papilla formation in response to powdery mildew fungi penetration by interacting with SYNTAXIN OF PLANTS121 in Arabidopsis.	Nitrogen	11-19	syntaxin	Arabidopsis thaliana	159-167
24200968-8	2014	miR-888 also increased colony formation in PC3-N and LNCaP cells, supporting an oncogenic role for this miRNA in the prostate.	Nitrogen	47-48	proprotein convertase subtilisin/kexin type 1	Homo sapiens	43-46
24076354-8	2014	In agreement with a previously reported LECT2 sequence, the predicted amino acid sequence contains characteristic phosphorylation and N-glycosylation sites.	Nitrogen	134-135	leukocyte cell-derived chemotaxin-2	Anas platyrhynchos	40-45
22243251-2	2011	Pig and mouse KLK4 contain three potential N-glycosylation sites.	Nitrogen	43-44	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	Mus musculus	14-18
22243251-3	2011	We isolated KLK4 from developing pig and mouse molars and characterized their N-glycosylations.	Nitrogen	78-79	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	Mus musculus	12-16
21942440-0	2011	Amperometric detection of L-lactate using nitrogen-doped carbon nanotubes modified with lactate oxidase.	Nitrogen	42-50	lysyl oxidase	Homo sapiens	88-103
24533364-15	2014	CPAP therapy (N = 20) lessened awake time, decreased N2 and increased REM.	Nitrogen	53-55	centromere protein J	Homo sapiens	0-4
25378205-5	2014	RESULTS: After intravenous administration of HGF at doses of 0.5-2.0 mg/kg, the elevation of blood urea nitrogen was suppressed, indicating that HGF had a pharmacodynamic effect.	Nitrogen	104-112	hepatocyte growth factor	Rattus norvegicus	45-48
25378205-5	2014	RESULTS: After intravenous administration of HGF at doses of 0.5-2.0 mg/kg, the elevation of blood urea nitrogen was suppressed, indicating that HGF had a pharmacodynamic effect.	Nitrogen	104-112	hepatocyte growth factor	Rattus norvegicus	145-148
24193351-3	2014	Baseline examinations were performed under atmospheric air conditions at 341 meters above sea level (FIO2 of 21 %), and were compared to hypoxia (FIO2 of 13.2 %) by breathing a nitrogen-enriched gas mixture for 45 min.	Nitrogen	177-185	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	90-93
24474629-0	2014	NITROGEN LIMITATION ADAPTATION recruits PHOSPHATE2 to target the phosphate transporter PT2 for degradation during the regulation of Arabidopsis phosphate homeostasis.	Nitrogen	0-8	phosphate 2	Arabidopsis thaliana	40-50
24474629-1	2014	The NITROGEN LIMITATION ADAPTION (NLA) gene was initially shown to function in nitrogen limitation responses; however, recent work shows that the nla mutant hyperaccumulates Pi, phenocopying the Pi signaling mutant pho2.	Nitrogen	4-12	phosphate 2	Arabidopsis thaliana	215-219
24474629-1	2014	The NITROGEN LIMITATION ADAPTION (NLA) gene was initially shown to function in nitrogen limitation responses; however, recent work shows that the nla mutant hyperaccumulates Pi, phenocopying the Pi signaling mutant pho2.	Nitrogen	79-87	phosphate 2	Arabidopsis thaliana	215-219
21932778-5	2011	Experiments using the drug tunicamycin to inhibit the N-linked glycosylation of glypican-1 showed that secretion of anchorless glypican-1 was reduced and that the protein did not accumulate inside the cells.	Nitrogen	54-55	glypican 1	Homo sapiens	127-137
21932778-7	2011	N-Glycosylation mutants and N-deglycosylated glypican-1 had far-UV circular dichroism and fluorescence emission spectra that were highly similar to those of N-glycosylated glypican-1.	Nitrogen	0-1	glypican 1	Homo sapiens	172-182
21932778-7	2011	N-Glycosylation mutants and N-deglycosylated glypican-1 had far-UV circular dichroism and fluorescence emission spectra that were highly similar to those of N-glycosylated glypican-1.	Nitrogen	28-29	glypican 1	Homo sapiens	45-55
21932778-7	2011	N-Glycosylation mutants and N-deglycosylated glypican-1 had far-UV circular dichroism and fluorescence emission spectra that were highly similar to those of N-glycosylated glypican-1.	Nitrogen	28-29	glypican 1	Homo sapiens	172-182
31773048-8	2014	We found that N- and C-terminal fragments, encoding multiple motifs including sequences involved in binding integrins and CD44, a domain know to promote adhesion contribute to OPN"s ability to increase HIV replication.	Nitrogen	14-15	secreted phosphoprotein 1	Homo sapiens	176-179
21932778-8	2011	A single unfolding transition at high concentrations of urea was found for both N-deglycosylated glypican-1 and glypican-1 in which the N-glycosylation sites had been removed by mutagenesis when chemical denaturation was monitored by circular dichroism and fluorescence emission spectroscopy.	Nitrogen	80-81	glypican 1	Homo sapiens	97-107
21932778-9	2011	In summary, we have found that the potential N-glycosylation sites in glypican-1 are invariably occupied and that the N-linked glycans on glypican-1 affect protein expression and heparan sulfate substitution but that correct folding can be obtained in the absence of N-linked glycans.	Nitrogen	45-46	glypican 1	Homo sapiens	70-80
21576477-1	2013	Crop-livestock production systems are the largest cause of human alteration of the global nitrogen (N) and phosphorus (P) cycles.	Nitrogen	90-98	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	0-4
24234751-6	2014	Moreover, deviations of the electrophoretic molecular weight (MW) of the HCN isoforms relative to the theoretical MW were observed, suggesting that N-glycosylation and enzymatic proteolysis influences HCN channel surface expression.	Nitrogen	75-76	cyclic nucleotide gated channel subunit alpha 1	Rattus norvegicus	201-204
24121369-1	2013	A FBR-MBR combo system was designed as a novel approach for simultaneous phosphorus and nitrogen removal from sewage.	Nitrogen	88-96	translocator protein	Homo sapiens	6-9
32481189-0	2013	Overexpression of miR160 affects root growth and nitrogen-fixing nodule number in Medicago truncatula.	Nitrogen	49-57	MIR160a	Arabidopsis thaliana	18-24
21967807-9	2011	The model included two hydrophobes and a positive nitrogen as relevant features and it was able to discriminate between molecules with and without affinity toward sigma(1) receptor subtype.	Nitrogen	50-58	sigma non-opioid intracellular receptor 1	Rattus norvegicus	163-180
24515454-1	2014	Mammalian glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, interconnecting carbon skeleton and nitrogen metabolism.	Nitrogen	167-175	glutamate dehydrogenase 1	Homo sapiens	10-33
22023369-2	2011	Here, we present the 2.2-A structure of the complex formed between nonfucosylated IgG1-Fc and a soluble form of FcgammaRIIIa (sFcgammaRIIIa) with two N-glycosylation sites.	Nitrogen	150-151	Fc gamma receptor IIIa	Homo sapiens	112-124
21921116-8	2011	Metabolic and transcript profiling revealed that mild deficiency in SDH results in limited effects on metabolism and gene expression, and data suggest that decreases observed in the levels of some amino acids were due to a higher flux to proteins and other nitrogen-containing compounds to support increased growth.	Nitrogen	257-265	lysine-ketoglutarate reductase/saccharopine dehydrogenase bifunctional enzyme	Arabidopsis thaliana	68-71
24205994-1	2013	In this work is investigated why the entrance of a nitrogen atom in the ring of cis-2-hydroxypyridine and 2-pyridinone, resulting in cis-4-hydroxypyrimidine and 4(3H)-pyrimidinone, respectively, shifts the tautomeric equilibrium from the hydroxyl form, in the pyridine derivative, to the ketonic form, in the pyrimidine derivative.	Nitrogen	51-59	suppressor of cytokine signaling 2	Homo sapiens	80-85
24081306-3	2013	The change of the working gas from zero air to N2 allows us to change the major reactant ions from NO(+) (H2O)n to H3O(+) (H2O)n. In this paper we present the description of the new CD-APCI and discuss the processes associated with the NO(+) formation.	Nitrogen	47-49	H3 clustered histone 15	Homo sapiens	115-121
24515454-1	2014	Mammalian glutamate dehydrogenase (GDH) catalyzes the reversible inter-conversion of glutamate to alpha-ketoglutarate and ammonia, interconnecting carbon skeleton and nitrogen metabolism.	Nitrogen	167-175	glutamate dehydrogenase 1	Homo sapiens	35-38
21924344-11	2011	In type 1 diabetic rats, ST-3 supplement for three weeks caused significant reduction in fasting blood glucose, total cholesterol, triglyceride, urea nitrogen, creatinine and liver mass, along with significantly inhibiting the decline of insulin level compared to diabetic control (p&lt;0.05 or p&lt;0.01).	Nitrogen	150-158	matrix metallopeptidase 11	Rattus norvegicus	25-29
24211622-2	2014	Co(I) atom has a distorted trigonal pyramidal N2S2 (1) environment with two S atoms and one N atom from three mu-1,1,3-thiocyanate bridge ligands and one N atom from ql ligand.	Nitrogen	46-47	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	0-5
24447198-6	2013	Although there is some evidence to suggest that n-3 PUFA intake is associated with reduced depressive symptoms, particularly in females, these results are generally limited to epidemiological studies, whereas results from randomized controlled trials are mixed.	Nitrogen	28-29	pumilio RNA binding family member 3	Homo sapiens	52-56
24147127-5	2013	We observed significant changes in gene expression of enzymes involved in nitrogen and glucose metabolism and their local distribution following CCl4 injury.	Nitrogen	74-82	chemokine (C-C motif) ligand 4	Mus musculus	145-149
23921072-6	2013	LC-MS analysis confirmed that full-length melanopsin-L was expressed and demonstrated that the majority of the expressed protein was N-glycosylated at Asn(30) and Asn(34).	Nitrogen	133-134	opsin 4 (melanopsin)	Mus musculus	42-52
22005411-0	2011	Evaluation of breed effects on n-3 PUFA metabolism with dietary flaxseed oil supplementation in dogs.	Nitrogen	9-10	pumilio RNA binding family member 3	Homo sapiens	35-39
21527438-0	2011	N-glycosylation controls trafficking, zymogen activation and substrate processing of proprotein convertases PC1/3 and subtilisin kexin isozyme-1.	Nitrogen	0-1	membrane bound transcription factor peptidase, site 1	Homo sapiens	118-144
24211622-2	2014	Co(I) atom has a distorted trigonal pyramidal N2S2 (1) environment with two S atoms and one N atom from three mu-1,1,3-thiocyanate bridge ligands and one N atom from ql ligand.	Nitrogen	92-93	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	0-5
21843961-7	2011	Dependence of T(1) on nitrogen nuclear spin state m(I) was observed for both (14)N and (15)N. Unresolved hydrogen/deuterium hyperfine couplings dominate overall line widths.	Nitrogen	22-30	spindlin 1	Homo sapiens	39-43
23897395-1	2013	Nitrogen enriched mesoporous carbon (N-MCS) with extremely high mesopore volume and nitrogen content is prepared through a one-step hard template method.	Nitrogen	0-8	Miles-Carpenter X-linked mental retardation syndrome	Homo sapiens	39-42
23897395-1	2013	Nitrogen enriched mesoporous carbon (N-MCS) with extremely high mesopore volume and nitrogen content is prepared through a one-step hard template method.	Nitrogen	84-92	Miles-Carpenter X-linked mental retardation syndrome	Homo sapiens	39-42
24120458-8	2014	For the precursors, more HCN was detected than NH3 and both played important roles on the gas side nitrogen evolution.	Nitrogen	99-107	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	25-28
24007272-3	2013	RESULTS: Partial sequences of five genes related to N-metabolism in barley (Hordeum vulgare L.) were obtained, i.e. nitrate reductase 1, glutamine synthetase 2, ferredoxin-dependent glutamate synthase, aspartate aminotransferase and asparaginase.	Nitrogen	52-53	ferredoxin-dependent glutamate synthase, Fd-GOGAT	Hordeum vulgare	161-200
21951810-8	2011	In addition of these three genes that were also top-ranked by NormFinder, two extra genes: CYP18-2 (Cyclophilin A, AY456122.1) and TaWIN1 (14-3-3 like protein, AB042193) were most consistently stably expressed.Furthermore, we showed that TaFNRII, ACT2, and CYP18-2 are suitable for gene expression normalization in other two winter wheat varieties (Tommi and Centenaire) grown under three treatments (organic, conventional and no nitrogen) and a different environment than the one tested with cv.	Nitrogen	430-438	14-3-3-like protein GF14-D	Triticum aestivum	131-158
23824663-2	2014	Proline-fueled mitochondrial metabolism involves the oxidative conversion of L-Proline to L-Glutamate in two enzymatic steps by means of Put1p and Put2p that help Saccharomyces cerevisiae to respond to changes in the nutritional environment by initiating the breakdown of L-Proline as a source for nitrogen, carbon, and energy.	Nitrogen	298-306	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	147-152
21866314-2	2011	We compared the activity of synthetic rat N-terminal POMC fragment 1-28 with disulfide bridges (N-POMC(w)) and without disulfide bridges (N-POMC(w/o)), with the activity of fibroblast growth factor (FGF2), a widely studied adrenal growth factor, and ACTH, in well-characterized pure cultures of both isolated adrenal Glomerulosa (G) and Fasciculata/Reticularis (F/R) cells.	Nitrogen	42-43	proopiomelanocortin	Rattus norvegicus	53-57
24005034-3	2013	The immobilization of His6-RAGE domains consists of: (i) formation of a mixed layer of N-acetylcysteamine (NAC) and the thiol derivative of pentetic acid (DPTA); (ii) complexation of Cu(II) by DPTA; (iii) oriented immobilization of His6-RAGE domains via coordination bonds between Cu(II) sites from DPTA-Cu(II) complex and imidazole nitrogen atoms of a histidine tag.	Nitrogen	333-341	advanced glycosylation end-product specific receptor	Homo sapiens	27-31
24391791-1	2013	The spatial variability of soil organic carbon (SOC) and total nitrogen (STN) levels is important in both global carbon-nitrogen cycle and climate change research.	Nitrogen	63-71	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	73-76
23816043-2	2013	Ethyl 2"-oxa-1,2,3,5,6,7-hexahydrospiro[4H-azepine-4,3"-3H-indole]-1"-carboxylate scaffold was functionalized at nitrogen azepino ring with Aib-(l/d)Trp-OH dipeptides.	Nitrogen	113-121	ANIB1	Homo sapiens	140-143
21791552-6	2011	Regression analysis revealed that CD34+, CD34+/KDR+ and CD34+/CD45- hematopoietic CPCs were associated positively with eGFR and negatively with blood urea nitrogen and serum creatinine.	Nitrogen	155-163	protein tyrosine phosphatase receptor type C	Homo sapiens	62-66
21486309-0	2011	Water-use efficiency and nitrogen-use efficiency of C(3) -C(4) intermediate species of Flaveria Juss.	Nitrogen	25-33	complement C3	Homo sapiens	52-56
24391791-1	2013	The spatial variability of soil organic carbon (SOC) and total nitrogen (STN) levels is important in both global carbon-nitrogen cycle and climate change research.	Nitrogen	120-128	eukaryotic translation elongation factor 1 alpha 2	Homo sapiens	73-76
21676880-0	2011	Post-translational N-glycosylation of type I transmembrane KCNE1 peptides: implications for membrane protein biogenesis and disease.	Nitrogen	19-20	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	59-64
24100040-5	2013	Our data also suggest that FDX3 is involved in nitrogen assimilation, FDX4 in glycolysis and response to reactive oxygen species, and FDX5 in hydrogenase maturation.	Nitrogen	47-55	uncharacterized protein	Chlamydomonas reinhardtii	27-31
21676880-2	2011	Here, we examine the kinetics of N-glycan addition to type I transmembrane KCNE1 K(+) channel beta-subunits, where point mutations that prevent N-glycosylation at one consensus site give rise to disorders of the cardiac rhythm and congenital deafness.	Nitrogen	33-34	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	75-80
21676880-5	2011	This long range inhibition is highly specific for post-translational N-glycosylation because mutagenic conversion of the KCNE1 post-translational site into a co-translational site restored both monoglycosylation and anterograde trafficking.	Nitrogen	69-70	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	121-126
23881381-5	2013	Intake of total long chain n-3 PUFA was compared to the energy adjusted suggested dietary target (SDT) for Australian children and 20 % of children who ate fish during the 2 days of the survey met the SDT.	Nitrogen	1-2	pumilio RNA binding family member 3	Homo sapiens	31-35
24021350-6	2013	Structure-activity relationship showed nitrogen-containing monocyclic rings and noncyclic substituents at the 4- and 8-positions of the pyrimido[5,4-d]pyrimidine were important for the inhibitory activity against hENT4.	Nitrogen	39-47	solute carrier family 29 member 4	Homo sapiens	213-218
23831944-5	2013	NQO1-/- mice showed increased blood urea nitrogen and creatinine levels, tubular damage, oxidative stress, and apoptosis.	Nitrogen	41-49	NAD(P)H dehydrogenase, quinone 1	Mus musculus	0-4
23991019-8	2013	Treatment with a beta1-integrin function-blocking antibody, AIIB2, preferentially decreased the N-glycosylated form of beta1-integrin, impaired mammosphere formation and restored epithelial phenotype in mesenchymal colony clusters.	Nitrogen	96-97	integrin subunit beta 1	Homo sapiens	17-31
23092637-10	2013	CONCLUSIONS: The PCK1 rs2179706 polymorphism interacts with plasma concentration of n - 3 PUFA levels modulating insulin resistance in MetS subjects.	Nitrogen	46-47	pumilio RNA binding family member 3	Homo sapiens	90-94
23739770-9	2013	In the H and HF group, the expression of HIF-1alpha was significantly increased on P12 compared with the N group (P&lt;0.05).	Nitrogen	105-106	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	41-51
23739770-10	2013	On P19 and P21, HIF-1alpha expression was significantly increased to a maximum level in the HF group compared with the H and N group (P&lt;0.01).	Nitrogen	125-126	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	16-26
21678509-1	2011	The synthesis of Ru-based precatalysts with N-heterocyclic carbene (NHC) ligands bearing syn- and anti-methyl groups on the NHC backbone and aryl N-substituents with differing steric bulk was carried out.	Nitrogen	44-45	synemin	Homo sapiens	4-7
21671682-3	2011	Sulfidefluor-1 (SF1) and Sulfidefluor-2 (SF2) respond to H(2)S by a turn-on fluorescence signal enhancement and display high selectivity for H(2)S over other biologically relevant reactive sulfur, oxygen, and nitrogen species.	Nitrogen	209-217	splicing factor 1	Homo sapiens	16-19
21671682-3	2011	Sulfidefluor-1 (SF1) and Sulfidefluor-2 (SF2) respond to H(2)S by a turn-on fluorescence signal enhancement and display high selectivity for H(2)S over other biologically relevant reactive sulfur, oxygen, and nitrogen species.	Nitrogen	209-217	serine and arginine rich splicing factor 1	Homo sapiens	41-44
21111853-4	2011	The considerably more potent nitrogen-containing bisphosphonates are not metabolised but potently inhibit farnesyl pyrophosphate (FPP) synthase, a key enzyme of the mevalonate pathway.	Nitrogen	29-37	farnesyl diphosphate synthase	Homo sapiens	106-143
24078118-4	2013	The N-glycosylation site of rNPI was analyzed by nano LC-MS/MS after digesting by trypsin and Glu-C, and the unique potential site Asn41 of mature peptide was found to be glycosylated.	Nitrogen	4-5	neuronal pentraxin 1	Rattus norvegicus	28-32
24227656-8	2013	We conclude that MGAT1-dependent N-glycosylation shapes the synaptomatrix carbohydrate environment and endogenous lectin localization within this domain, to modulate retention of trans-synaptic signaling ligands driving synaptic scaffold recruitment during synaptogenesis.	Nitrogen	33-34	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	17-22
21491538-4	2011	As a result, the fluorescent dye is brought into close proximity to CPN and substantial fluorescence quenching occurs due to photoinduced electron transfer from the nitrogen atom in CPN to the excited fluorophore.	Nitrogen	165-173	carboxypeptidase N subunit 1	Homo sapiens	182-185
24144945-2	2013	Dolichol kinase (DOLK) catalyzes the final step in biosynthesis of dolichol phosphate (Dol-P), which is the oligosaccharide carrier required for protein N-glycosylation.	Nitrogen	153-154	dolichol kinase	Homo sapiens	0-15
21555241-2	2011	Under limiting nitrogen conditions, the ammonium permease Mep2 induces the switch from yeast to filamentous growth.	Nitrogen	15-23	ammonium permease MEP2	Saccharomyces cerevisiae S288C	58-62
21555241-3	2011	Mep2 is a cytoplasmic membrane protein that mediates uptake of the preferred nitrogen source ammonium.	Nitrogen	77-85	ammonium permease MEP2	Saccharomyces cerevisiae S288C	0-4
24144945-2	2013	Dolichol kinase (DOLK) catalyzes the final step in biosynthesis of dolichol phosphate (Dol-P), which is the oligosaccharide carrier required for protein N-glycosylation.	Nitrogen	153-154	dolichol kinase	Homo sapiens	17-21
21521696-1	2011	The Arabidopsis (Arabidopsis thaliana) soluble N-ethylmaleimide-sensitive factor attachment protein receptor SYP41 is involved in vesicle fusion at the trans-Golgi network (TGN) and interacts with AtVPS45, SYP61, and VTI12.	Nitrogen	47-48	vacuolar protein sorting 45	Arabidopsis thaliana	197-204
23988488-9	2013	Using the relative activity factor approach, the hepatic clearance was calculated to be 27 and 73% for 2-O-demethylation by CYP1A2 and CYP3A4, 82, 3, and 15% for 9-O-demethylation by CYP1A2, CYP2C19, and CYP2D6, and finally &lt;1 and 99% for N-demethylation by CYP2D6 and CYP3A4.	Nitrogen	242-243	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	124-130
21521696-1	2011	The Arabidopsis (Arabidopsis thaliana) soluble N-ethylmaleimide-sensitive factor attachment protein receptor SYP41 is involved in vesicle fusion at the trans-Golgi network (TGN) and interacts with AtVPS45, SYP61, and VTI12.	Nitrogen	47-48	syntaxin of plants 61	Arabidopsis thaliana	206-211
24121110-6	2013	We found that heparin binding basic residues, hD helix, three pairs of Cys-Cys salt bridges, N-glycosylation sites, serpin motifs and inhibitory reactive center loop (RCL) of ATIII protein are highly conserved.	Nitrogen	93-94	serpin family C member 1	Homo sapiens	175-180
21525271-3	2011	Expressing chimeric GluN2 subunits, we identified a putative N-glycosylation site present in GluN2B, but not in GluN2A, as necessary and sufficient to drive NMDARs into synapses in an activity-independent manner.	Nitrogen	23-24	glutamate ionotropic receptor NMDA type subunit 2B	Rattus norvegicus	93-99
24102289-1	2013	Allylic amination reactions of alkenes, with an NBP (N-bromophthalimide) or NBS (N-bromosuccinimide)/DBU combination, were developed, in which both internal and external nitrogen nucleophiles can be installed directly.	Nitrogen	170-178	nibrin	Homo sapiens	76-79
21131470-8	2011	Importantly, patients with asthma with cross-linked SP-D demonstrated significantly higher levels of BAL eosinophils, nitrogen oxides, IL-4, IL-5, IL-13, and S-nitrosothiol-SP-D compared with patients without cross-linked SP-D.	Nitrogen	118-126	surfactant protein D	Homo sapiens	52-56
24102289-2	2013	Dual activation of NBS or NBP by DBU leads to more electrophilic bromine and more nucleophilic nitrogen atoms simultaneously.	Nitrogen	95-103	nibrin	Homo sapiens	19-22
21323370-6	2011	CXCR1 undergoes rapid rotational diffusion about the normal of liquid crystalline phospholipid bilayers; reductions in the frequency span and a change to axial symmetry are observed for both carbonyl carbon and amide nitrogen chemical shift powder patterns of unoriented samples containing (13)C- and (15)N-labeled CXCR1.	Nitrogen	217-225	C-X-C motif chemokine receptor 1	Homo sapiens	0-5
21323370-6	2011	CXCR1 undergoes rapid rotational diffusion about the normal of liquid crystalline phospholipid bilayers; reductions in the frequency span and a change to axial symmetry are observed for both carbonyl carbon and amide nitrogen chemical shift powder patterns of unoriented samples containing (13)C- and (15)N-labeled CXCR1.	Nitrogen	305-306	C-X-C motif chemokine receptor 1	Homo sapiens	0-5
23764502-8	2013	The glycans on PSA are believed to be biantennary N-linked, and it has been observed that prostate cancer tissues and cell lines contain more antennae than their benign counterparts.	Nitrogen	50-51	kallikrein related peptidase 3	Homo sapiens	15-18
23884140-7	2013	Continuous infusion of P78-PEDF for 6 wk resulted in protection from diabetic neuropathy as indicated by reduced albuminuria and blood urea nitrogen, increased nephrin expression, decreased kidney macrophage recruitment and inflammatory cytokines, and reduced histological changes compared with vehicle-treated diabetic mice.	Nitrogen	140-148	microspherule protein 1	Mus musculus	23-26
21479233-6	2011	The extracellular domain of feline Tetherin/BST-2 has two putative N-linked glycosylation sites, N79 and N119.	Nitrogen	67-68	bone marrow stromal cell antigen 2	Homo sapiens	35-43
21479233-6	2011	The extracellular domain of feline Tetherin/BST-2 has two putative N-linked glycosylation sites, N79 and N119.	Nitrogen	67-68	bone marrow stromal cell antigen 2	Homo sapiens	44-49
21278231-1	2011	The ammonium permease Mep2 induces a switch from unicellular yeast to filamentous growth in response to nitrogen limitation in Saccharomyces cerevisiae and Candida albicans.	Nitrogen	104-112	ammonium permease MEP2	Saccharomyces cerevisiae S288C	22-26
21278231-3	2011	Mutants lacking NPR1 cannot grow on low concentrations of ammonium and do not filament under limiting nitrogen conditions.	Nitrogen	102-110	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	16-20
21278231-8	2011	However, the dependence of Mep2 activity on Npr1 was relieved at higher temperatures (37 C), and Mep2 could efficiently induce filamentous growth under limiting nitrogen conditions in npr1Delta mutants.	Nitrogen	161-169	ammonium permease MEP2	Saccharomyces cerevisiae S288C	97-101
23761407-5	2013	Consistent with its nuclear localization, N2 inhibits IRF3 downstream of the TANK-binding kinase (TBK)-1 and after IRF3 translocation into the nucleus.	Nitrogen	42-44	TANK binding kinase 1	Homo sapiens	77-104
21247791-3	2011	Nitrogen-containing bisphosphonates (N-BPs) are particularly able to inhibit pyrophosphate synthase (FPPS) in the mevalonate pathway (MVP).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	101-105
21522366-1	2011	There are two half-mol-ecules in the asymmetric unit of the title compound, C(32)H(30)Cl(4)N(4), in both of which the N-H bonds are syn to the meta-chloro substituents in the adjacent benzene ring.	Nitrogen	91-92	synemin	Homo sapiens	132-135
23483653-2	2013	The additional role of PTS(Ntr) as a regulatory link between nitrogen and carbon utilization in Escherichia coli is assumed to be closely related to molecular functions of IIA(Ntr) in potassium homeostasis.	Nitrogen	61-69	colicin Ia immunity protein	Escherichia coli	172-175
20970123-0	2011	Inhibition of CD44 N- and O-linked glycosylation decreases endometrial cell lines attachment to peritoneal mesothelial cells.	Nitrogen	19-20	CD44 molecule (Indian blood group)	Homo sapiens	14-18
20970123-2	2011	Inhibition of CD44 N- and O-linked glycosylation by using tunicamycin and/or B-GalNAc statistically significantly inhibited endometrial cell attachment to peritoneal mesothelial cells, suggesting a role in establishment of early endometriotic lesions.	Nitrogen	19-20	CD44 molecule (Indian blood group)	Homo sapiens	14-18
23481038-3	2013	Our group recently described its involvement in mitochondrial biogenesis and stress resistance, and reports here that Hcm1 played a role in adaptation to respiratory metabolism when glucose or nitrogen was decreased.	Nitrogen	193-201	Hcm1p	Saccharomyces cerevisiae S288C	118-122
21122888-5	2011	Comparing different wastewater treatment methods, we found lower concentrations in those using biological nitrogen and phosphorous elimination, suggesting that DP is susceptible to microbial degradation and that anti-DP is more so, given the enrichment of syn-DP in the sewage sludge.	Nitrogen	106-114	synemin	Homo sapiens	256-259
23701949-6	2013	Rather more, abundantly present Stx5 was capable of translocating ER-/N-glycosylated VLDL-R to the plasma membrane, and thus was insensitive to BFA treatment and low temperature.	Nitrogen	70-71	very low density lipoprotein receptor	Homo sapiens	85-91
20859794-4	2011	The specificity and potency of these compounds for blocking PDE action have been improved by appending groups at positions on the rings as well as by modification of the number and distribution of nitrogens and carbons in those rings.	Nitrogen	197-206	aldehyde dehydrogenase 7 family member A1	Homo sapiens	60-63
22634058-10	2013	The N-in-one screening assay seems useful and reliable for most CYP activities when a comprehensive and quick evaluation of potential interactions with CYPs is needed.	Nitrogen	4-5	peptidylprolyl isomerase G	Homo sapiens	64-67
22072933-2	2011	Three-dimensional quantitative structure-activity relationship (3D-QSAR) studies were performed on a set of alpha(1A)-AR antagonists of N-aryl and N-nitrogen class.	Nitrogen	147-157	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	108-116
23886338-7	2013	Moreover, lowering the dietary n-6: n-3 FAR led to an increase in the expression of the pre-synaptic protein synaptophysin in the CA1 hippocampal subregion of the rat brain.	Nitrogen	16-17	carbonic anhydrase 1	Rattus norvegicus	130-133
20506028-2	2011	ChM-I comprises two domains: an N-terminal hydrophilic domain (domain 1) containing an N-linked glycosylation site and a C-terminal hydrophobic domain (domain 2) with all four disulfide bonds that are present in this protein.	Nitrogen	32-33	chondromodulin	Homo sapiens	0-5
20506028-5	2011	Although domain 1 is predicted to be hydrophilic per se on the basis of its amino acid sequence, NG-hChM-I remains insoluble in aqueous solution as much as DeltaN-hChM-I that lacks the N-terminal 37 amino acids containing an N-glycosylation site.	Nitrogen	97-98	chondromodulin	Homo sapiens	100-106
23887631-3	2013	Using n-myc amplified SK-N-Be(2)C and non-n-myc amplified SK-N-SH human neuroblastoma cells, our laboratory generated doxorubicin-resistant cell lines in parallel over 1 year; one cell line intermittently treated with the histone deacetylase inhibitor (HDACi) vorinostat and the other without exposure to HDACi.	Nitrogen	24-26	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	6-11
21535678-4	2011	Km(app) values (mM) for apple PPO in 3%O(2)/97%Ar, 3%O(2)/97%N(2), and air, were 133, 87, and 48, respectively.	Nitrogen	61-62	polyphenol oxidase, chloroplastic	Malus domestica	30-33
23760501-8	2013	Using newly developed antibodies that specifically recognize the CerS6 protein we show that the endogenous CerS6 protein is N-glycosylated and expressed in several tissues of mice, mainly kidney, small and large intestine, and brain.	Nitrogen	124-125	ceramide synthase 6	Mus musculus	65-70
21091557-12	2011	In contrast, under nitrogen but not phosphorus limitation, MED4 rapidly downregulated ribosomal proteins.	Nitrogen	19-27	mediator complex subunit 4	Homo sapiens	59-63
21091557-13	2011	MED4"s specific, rapid nitrogen response suggests adaptation to fluctuating conditions, supporting previous work.	Nitrogen	23-31	mediator complex subunit 4	Homo sapiens	0-4
23760501-8	2013	Using newly developed antibodies that specifically recognize the CerS6 protein we show that the endogenous CerS6 protein is N-glycosylated and expressed in several tissues of mice, mainly kidney, small and large intestine, and brain.	Nitrogen	124-125	ceramide synthase 6	Mus musculus	107-112
23837681-4	2013	RESULTS: The open-source software "Least Square Mass Isotopomer Analyzer" (LS-MIDA) is presented that processes experimental mass spectrometry (MS) data on the basis of metabolite information such as the number of atoms in the compound, mass to charge ratio (m/e or m/z) values of the compounds and fragments under study, and the experimental relative MS intensities reflecting the enrichments of isotopomers in 13C- or 15 N-labelled compounds, in comparison to the natural abundances in the unlabelled molecules.	Nitrogen	423-424	NADH:ubiquinone oxidoreductase complex assembly factor 7	Homo sapiens	78-82
21625387-6	2011	A significant reduction of CDK5R1 mRNA and p35 levels was observed after transfection of SK-N-BE neuroblastoma cells with the miR-103 or miR-107 precursor (pre-miR-103 or pre-miR-107).	Nitrogen	36-37	cyclin dependent kinase 5 regulatory subunit 1	Homo sapiens	27-33
21902027-2	2011	For the treatment of synthetic wastewater, the combined system exhibited a high TOC removal of 98% with a steady ammonia removal efficiency of about 98% in the MBR and a total nitrogen (TN) removal efficiency of 90%.	Nitrogen	176-184	rhomboid 5 homolog 2	Homo sapiens	80-83
24216356-5	2013	Total NO-N losses from the sandy soil were higher after amendment with BR-B (0.32 g NO-N m) than BR-A or CS (0.02 and 0.18 g NO-N m, respectively).	Nitrogen	6-7	brain ribonuclease	Bos taurus	71-75
21118617-8	2010	Advice to specifically increase n-6 PUFA intake, based on mixed n-3/n-6 RCT data, is unlikely to provide the intended benefits, and may actually increase the risks of CHD and death.	Nitrogen	24-25	pumilio RNA binding family member 3	Homo sapiens	36-40
21118617-8	2010	Advice to specifically increase n-6 PUFA intake, based on mixed n-3/n-6 RCT data, is unlikely to provide the intended benefits, and may actually increase the risks of CHD and death.	Nitrogen	24-25	choline dehydrogenase	Homo sapiens	167-170
20952580-0	2010	Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism.	Nitrogen	77-85	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	0-4
20952580-0	2010	Hal4 and Hal5 protein kinases are required for general control of carbon and nitrogen uptake and metabolism.	Nitrogen	77-85	protein kinase HAL5	Saccharomyces cerevisiae S288C	9-13
20952580-9	2010	These results indicate that the hal4 hal5 mutant presents defects in the general control of nitrogen and carbon metabolism, which correlate with reduced transport of amino acids and glucose, respectively.	Nitrogen	92-100	serine/threonine protein kinase SAT4	Saccharomyces cerevisiae S288C	32-36
20952580-9	2010	These results indicate that the hal4 hal5 mutant presents defects in the general control of nitrogen and carbon metabolism, which correlate with reduced transport of amino acids and glucose, respectively.	Nitrogen	92-100	protein kinase HAL5	Saccharomyces cerevisiae S288C	37-41
23760243-3	2013	We previously uncovered an unanticipated interaction between N and the largest subunit of the viral replicase-transcriptase complex, nonstructural protein 3 (nsp3).	Nitrogen	61-62	SH2 domain containing 3C	Homo sapiens	133-156
23760243-3	2013	We previously uncovered an unanticipated interaction between N and the largest subunit of the viral replicase-transcriptase complex, nonstructural protein 3 (nsp3).	Nitrogen	61-62	SH2 domain containing 3C	Homo sapiens	158-162
23760243-9	2013	The latter function of N was shown to depend on both of the RNA-binding domains of N, as well as on the serine- and arginine-rich central region of N, which binds nsp3.	Nitrogen	23-24	SH2 domain containing 3C	Homo sapiens	163-167
23703526-3	2013	Herein we show that activated endothelial cells express two distinct N-glycoforms of intercellular adhesion molecule 1 (ICAM-1) that comprise a complex N-glycoform with alpha-2,6 sialic acid present at relatively high levels and a second, less abundant and previously undescribed high-mannose glycoform (HM-ICAM-1).	Nitrogen	69-70	intercellular adhesion molecule 1	Homo sapiens	85-118
23703526-3	2013	Herein we show that activated endothelial cells express two distinct N-glycoforms of intercellular adhesion molecule 1 (ICAM-1) that comprise a complex N-glycoform with alpha-2,6 sialic acid present at relatively high levels and a second, less abundant and previously undescribed high-mannose glycoform (HM-ICAM-1).	Nitrogen	69-70	intercellular adhesion molecule 1	Homo sapiens	120-126
23703526-3	2013	Herein we show that activated endothelial cells express two distinct N-glycoforms of intercellular adhesion molecule 1 (ICAM-1) that comprise a complex N-glycoform with alpha-2,6 sialic acid present at relatively high levels and a second, less abundant and previously undescribed high-mannose glycoform (HM-ICAM-1).	Nitrogen	69-70	intercellular adhesion molecule 1	Homo sapiens	307-313
21143683-0	2010	TIP5;1 is an aquaporin specifically targeted to pollen mitochondria and is probably involved in nitrogen remobilization in Arabidopsis thaliana.	Nitrogen	96-104	tonoplast intrinsic protein 5;1	Arabidopsis thaliana	0-6
21143683-7	2010	Thus, we propose that TIP5;1 and TIP1;3 are involved in nitrogen recycling in pollen tubes of Arabidopsis thaliana.	Nitrogen	56-64	tonoplast intrinsic protein 5;1	Arabidopsis thaliana	22-28
23706549-2	2013	In the current study, N-(11)C-methylated compound of NCFB, [(11)C]Me-NCFB was synthesized and evaluated for the visualization of BACE1 in brain.	Nitrogen	22-25	beta-site APP cleaving enzyme 1	Mus musculus	129-134
21143683-7	2010	Thus, we propose that TIP5;1 and TIP1;3 are involved in nitrogen recycling in pollen tubes of Arabidopsis thaliana.	Nitrogen	56-64	Ankyrin repeat family protein with DHHC zinc finger domain-containing protein	Arabidopsis thaliana	33-37
21092300-9	2010	Eight studies presented adjusted odds ratios, ranging from 0.3 to 0.9, suggesting a reduced likelihood of self-reported sharing of non-N/S injecting paraphernalia associated with use of NSP or SIF.	Nitrogen	135-136	sperm antigen with calponin homology and coiled-coil domains 1	Homo sapiens	186-189
23776238-3	2013	The B-cell maturation antigen (BCMA), an essential membrane protein for maintaining the survival of plasma cells, was identified as a glycoprotein exhibiting complex-type N-glycans at a single N-glycosylation site, asparagine 42.	Nitrogen	171-172	TNF receptor superfamily member 17	Homo sapiens	4-29
23776238-3	2013	The B-cell maturation antigen (BCMA), an essential membrane protein for maintaining the survival of plasma cells, was identified as a glycoprotein exhibiting complex-type N-glycans at a single N-glycosylation site, asparagine 42.	Nitrogen	171-172	TNF receptor superfamily member 17	Homo sapiens	31-35
23776238-4	2013	We then investigated the effect of N-glycosylation on the function of BCMA and found that the dexamethasone-induced apoptosis in malignant plasma cells can be rescued by treatment with BCMA ligands, such as a proliferation-inducing ligand (APRIL) and B-cell-activating factor (BAFF), whereas removal of terminal sialic acid on plasma cells further potentiated the ligand-mediated protection.	Nitrogen	35-36	TNF receptor superfamily member 17	Homo sapiens	70-74
23776238-4	2013	We then investigated the effect of N-glycosylation on the function of BCMA and found that the dexamethasone-induced apoptosis in malignant plasma cells can be rescued by treatment with BCMA ligands, such as a proliferation-inducing ligand (APRIL) and B-cell-activating factor (BAFF), whereas removal of terminal sialic acid on plasma cells further potentiated the ligand-mediated protection.	Nitrogen	35-36	TNF receptor superfamily member 17	Homo sapiens	185-189
23748959-3	2013	The web server described here, the HIV N-linked Glycosylation Site Analyzer, was developed to facilitate study of HIV diversity by tracking gp120 N-linked glycosylation sites.	Nitrogen	39-40	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	140-145
23776238-7	2013	Together, our results highlight the importance of N-glycosylation on BCMA in the regulation of ligand binding and functions of plasma cells.	Nitrogen	50-51	TNF receptor superfamily member 17	Homo sapiens	69-73
21589477-2	2010	The mol-ecule adopts a syn-anti configuration with respect to the positions of the carbonyl groups and terminal phenyl rings relative to the thione S atom across the C-N bond.	Nitrogen	168-169	synemin	Homo sapiens	23-26
23606741-0	2013	OST4 is a subunit of the mammalian oligosaccharyltransferase required for efficient N-glycosylation.	Nitrogen	84-85	oligosaccharyltransferase complex subunit 4, non-catalytic	Homo sapiens	0-4
21075769-4	2010	AAP2 T-DNA insertion lines showed changes in source-sink translocation of amino acids and a decrease in the amount of seed total N and storage proteins, supporting AAP2 function in phloem loading and amino acid distribution to the embryo.	Nitrogen	8-9	amino acid permease 2	Arabidopsis thaliana	0-4
21075769-4	2010	AAP2 T-DNA insertion lines showed changes in source-sink translocation of amino acids and a decrease in the amount of seed total N and storage proteins, supporting AAP2 function in phloem loading and amino acid distribution to the embryo.	Nitrogen	8-9	amino acid permease 2	Arabidopsis thaliana	164-168
23703906-4	2013	In addition, loss of Miner1 caused a depletion of ER Ca(2+) stores, a dramatic increase in mitochondrial Ca(2+) load, increased reactive oxygen and nitrogen species, an increase in the GSSG/GSH and NAD(+)/NADH ratios, and an increase in the ADP/ATP ratio consistent with enhanced ATP utilization.	Nitrogen	148-156	CDGSH iron sulfur domain 2	Mus musculus	21-27
23666577-4	2013	O-demethylation is catalyzed by the highly polymorphic CYP2D6 and N-demethylation by several enzymes, CYP2C19, CYP2C9, and CYP3A4.	Nitrogen	66-67	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	102-109
23666577-5	2013	The observed overall pharmacokinetic effect was most probably the result of decreased N-demethylation of venlafaxine by (1) reduced expression of CYP2C19 due to a genetic deficit and (2) inhibition of CYP2C9 by cotrimoxazole.	Nitrogen	86-87	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	146-153
23535599-6	2013	Mass spectrometry showed that IpaJ cleaved the peptide bond between N-myristoylated glycine-2 and asparagine-3 of human ARF1, thereby providing a new mechanism for host secretory inhibition by a bacterial pathogen.	Nitrogen	68-69	ADP ribosylation factor 1	Homo sapiens	120-124
23556735-6	2013	The electron spin relaxation is attributed to the anisotropic part of the electron spin-nitrogen spin hyperfine interaction modulated by rotational dynamics of the paramagnetic molecule, and described by means of Redfield relaxation theory.	Nitrogen	88-96	spindlin 1	Homo sapiens	13-17
23556735-6	2013	The electron spin relaxation is attributed to the anisotropic part of the electron spin-nitrogen spin hyperfine interaction modulated by rotational dynamics of the paramagnetic molecule, and described by means of Redfield relaxation theory.	Nitrogen	88-96	spindlin 1	Homo sapiens	83-87
23556735-6	2013	The electron spin relaxation is attributed to the anisotropic part of the electron spin-nitrogen spin hyperfine interaction modulated by rotational dynamics of the paramagnetic molecule, and described by means of Redfield relaxation theory.	Nitrogen	88-96	spindlin 1	Homo sapiens	83-87
20830383-8	2010	This work provides a greater understanding of the influence of spin effects on the reactivities of anion reactions involving N and O atoms that may be important in the interstellar medium.	Nitrogen	125-126	spindlin 1	Homo sapiens	63-67
20739461-6	2010	During nitrogen starvation, Npr1 phosphorylation of Aly2 may stimulate Gap1 incorporation into AP-1/clathrin-coated vesicles to promote Gap1 trafficking from endosomes to the trans-Golgi network.	Nitrogen	7-15	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	28-32
23606741-10	2013	Strikingly, cells depleted of either OST4 or STT3A show a remarkably similar defect in the N-glycosylation of endogenous prosaposin.	Nitrogen	91-92	oligosaccharyltransferase complex subunit 4, non-catalytic	Homo sapiens	37-41
23606741-10	2013	Strikingly, cells depleted of either OST4 or STT3A show a remarkably similar defect in the N-glycosylation of endogenous prosaposin.	Nitrogen	91-92	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	45-50
20647741-5	2010	This requirement for Gcn2 and Gcn4 distinguishes amino-acid starvation induced autophagy from classic macroautophagy: Macroautophagic flux in response to nitrogen starvation is only partly diminished in gcn2Delta and gcn4Delta cells.	Nitrogen	154-162	serine/threonine-protein kinase GCN2	Saccharomyces cerevisiae S288C	21-25
23606741-11	2013	We conclude that OST4 most likely promotes co-translational N-glycosylation by stabilising STT3A-containing OST isoforms.	Nitrogen	60-61	oligosaccharyltransferase complex subunit 4, non-catalytic	Homo sapiens	17-21
20817882-7	2010	Recent seasonal H1N1 viruses expressed three to four N-glycosylation sequons on the head of hemagglutinin and were very sensitive to inhibition by SP-D or MBL, whereas A(H1N1) pandemic viruses expressed a single N-glycosylation sequon and were resistant to either collectin.	Nitrogen	18-19	surfactant protein D	Homo sapiens	147-151
20817882-7	2010	Recent seasonal H1N1 viruses expressed three to four N-glycosylation sequons on the head of hemagglutinin and were very sensitive to inhibition by SP-D or MBL, whereas A(H1N1) pandemic viruses expressed a single N-glycosylation sequon and were resistant to either collectin.	Nitrogen	53-54	surfactant protein D	Homo sapiens	147-151
23303461-1	2013	The fundamental reaction mechanism of cytochrome P450 2A6 (CYP2A6)-catalyzed N-methylhydroxylation of (S)-(-)-nicotine and the free energy profile have been studied by performing pseudobond first-principles quantum mechanical/molecular mechanical (QM/MM) reaction-coordinate calculations.	Nitrogen	77-78	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	38-57
23303461-1	2013	The fundamental reaction mechanism of cytochrome P450 2A6 (CYP2A6)-catalyzed N-methylhydroxylation of (S)-(-)-nicotine and the free energy profile have been studied by performing pseudobond first-principles quantum mechanical/molecular mechanical (QM/MM) reaction-coordinate calculations.	Nitrogen	77-78	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	59-65
23606741-11	2013	We conclude that OST4 most likely promotes co-translational N-glycosylation by stabilising STT3A-containing OST isoforms.	Nitrogen	60-61	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	91-96
23303461-3	2013	It has been demonstrated that the CYP2A6-catalyzed N-methylhydroxylation reaction is a concerted process involving a hydrogen-transfer transition state on both the quartet and the doublet states.	Nitrogen	51-52	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	34-40
23567996-1	2013	Human flavin-containing monooxygenase 3 (FMO3, EC 1.14.13.8) in liver catalyzes a variety of oxygenations of nitrogen- and sulfur-containing medicines and xenobiotic substances.	Nitrogen	109-117	Susceptibility to lysis by alloreactive natural killer cells	Homo sapiens	47-51
20890097-2	2010	Here we investigated by real time RT-PCR the dependence of expression levels of MET3, MET5/ECM17, MET10, MET16 and MET17 along with SSU1 on nitrogen availability in two wine yeast strains that produce divergent sulfide profiles.	Nitrogen	140-148	sulfite reductase subunit alpha	Saccharomyces cerevisiae S288C	98-103
23482579-2	2013	The objectives of this study were to evaluate RFI as a selection criterion to improve feed efficiency and its potential to reduce N and P excretion in 4 pig breeds.	Nitrogen	130-131	RFI	Sus scrofa	46-49
23307947-9	2013	This altered HA-hMC4R molecular mass was due to a change in endoglycosidase H-resistant complex N-linked glycosylation, which we observed for HA-hMC4R in both intracellular and cell surface fractions.	Nitrogen	96-97	melanocortin 4 receptor	Homo sapiens	16-21
23307947-9	2013	This altered HA-hMC4R molecular mass was due to a change in endoglycosidase H-resistant complex N-linked glycosylation, which we observed for HA-hMC4R in both intracellular and cell surface fractions.	Nitrogen	96-97	melanocortin 4 receptor	Homo sapiens	145-150
20547053-7	2010	UV-vis spectrophotometric determination of the GOx remains in the supernatant liquids after pH-induced CS precipitation suggested a high enzyme load in the GOx-GA-CS film, and amperometric measurements suggested a negligible decrease in the enzymatic activity of GOx after its reaction with the low-concentration GA. Also, the proposed protocol works well for the precrosslinking manner of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide/N-hydroxysulfosuccinimide activation, the water-electroreduction-triggered CS electrodeposition, the second-generation biosensing mode, a 5.0-microm-radius Pt ultramicroelectrode, and immobilization of alkaline phosphatase for phenyl phosphate biosensing.	Nitrogen	437-438	hydroxyacid oxidase 1	Homo sapiens	47-50
23434726-5	2013	Applying the (129)I exchange model, an estimate of total phosphorus and nitrogen inflow from the Baltic Proper to the Bothnian Sea indicates values of 20 +- 7 x 10(3) tons/y and 300 +- 50 x 10(3) tons/y respectively.	Nitrogen	72-80	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	127-130
20671743-13	2010	ECM/BCM ratio correlated directly with age (r=0.38, P=0.002) and inversely with serum albumin (r=-0.43, P=0.001), creatinine (-0.24, P=0.08), blood urea nitrogen (r=-0.26, P=0.06), and total protein (r=-0.31, P=0.026).	Nitrogen	153-161	TNF receptor superfamily member 17	Homo sapiens	4-7
20362058-6	2010	The results obtained demonstrated that recombinant hsp60 was secreted efficiently from cells when fused to the leader peptide of interleukin-2 and the secreted protein was modified by N-linked glycosylation.	Nitrogen	184-185	heat shock protein family D (Hsp60) member 1	Homo sapiens	51-56
23319596-8	2013	The N-glycosylation site at Asn-644 in the LOX catalytic domain is not conserved in human LOX (hLOX), although the LOX catalytic domain of hLOX shares ~50% identity and ~70% homology with hLOXL2.	Nitrogen	4-5	lysyl oxidase	Homo sapiens	43-46
23319596-8	2013	The N-glycosylation site at Asn-644 in the LOX catalytic domain is not conserved in human LOX (hLOX), although the LOX catalytic domain of hLOX shares ~50% identity and ~70% homology with hLOXL2.	Nitrogen	4-5	lysyl oxidase	Homo sapiens	139-143
23421677-4	2013	We propose that N-methylation of an arylazepine moiety, a frequent structural feature in 5-HT(2c) ligands, may be a suitable method for producing new radiotracers for 5-HT(2c).	Nitrogen	16-17	5-hydroxytryptamine receptor 2C	Homo sapiens	89-96
23421677-4	2013	We propose that N-methylation of an arylazepine moiety, a frequent structural feature in 5-HT(2c) ligands, may be a suitable method for producing new radiotracers for 5-HT(2c).	Nitrogen	16-17	5-hydroxytryptamine receptor 2C	Homo sapiens	167-174
23421677-9	2013	N-Methylation, with 16 +- 3% isolated radiochemical yield (decay corrected), is robust and may facilitate screening other 5-HT(2c) ligands as radiotracers for PET.	Nitrogen	0-1	5-hydroxytryptamine receptor 2C	Homo sapiens	122-129
23271734-0	2013	Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked beta-N-acetylglucosamine-substituted protein in human heart myofibrils.	Nitrogen	81-82	LIM domain binding 3	Homo sapiens	0-46
20463015-5	2010	Mutagenesis of S1P(1) showed a lack of requirement for N-linked glycosylation, tyrosine sulfation, or desensitization motifs but identified a requirement for transmembrane helix 4.	Nitrogen	55-56	sphingosine-1-phosphate receptor 1	Homo sapiens	15-21
23434726-6	2013	The values for the outflow from the Bothnian Sea to the Baltic Proper hold 12 +- 3 x 10(3) tons/y for total phosphorus and 283 +- 55 x 10(3) tons/y for total nitrogen.	Nitrogen	158-166	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	45-48
23271734-0	2013	Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked beta-N-acetylglucosamine-substituted protein in human heart myofibrils.	Nitrogen	81-82	zinc finger protein 469-like	Homo sapiens	48-52
23651256-2	2013	ARO9 and ARO10 are also under the control of nitrogen catabolite repression, but the direct roles for GATA factors, Gat1 and Gln3, in this regulation have not yet been elucidated.	Nitrogen	45-53	aromatic-amino-acid:2-oxoglutarate transaminase	Saccharomyces cerevisiae S288C	0-4
23289639-0	2013	Influence of surface adsorption on the interfacial electron transfer of flavin adenine dinucleotide and glucose oxidase at carbon nanotube and nitrogen-doped carbon nanotube electrodes.	Nitrogen	143-151	hydroxyacid oxidase 1	Homo sapiens	104-119
20526991-3	2010	Such epitopes recognized by six high-affinity monoclonal murine antibodies (mAbs) against human neutrophil gelatinase-associated lipocalin (NGAL) were determined by measuring chemical shifts or broadening of peaks in (1)H-(15)N-TROSY HSQC and (1)H-(13)C HSQC spectra of isotope-labeled NGAL occurring upon its binding to the antibodies.	Nitrogen	140-141	lipocalin 2	Homo sapiens	96-138
20406422-2	2010	In this study fluorescence protease protection assays and mutational analyses revealed the N- and C-terminal tails of CLN7 in the cytosol and two N-glycosylation sites at N371 and N376.	Nitrogen	91-92	major facilitator superfamily domain containing 8	Homo sapiens	118-122
23371306-3	2013	MBSelectin was developed by covalently binding an analog of the naturally occurring binding ligand P-selectin glycoprotein ligand 1 fused to a human fragment crystallizable(or Fc) domain onto the lipid shell of perfluorobutane and nitrogen-containing MBs.	Nitrogen	231-239	selectin P ligand	Homo sapiens	99-131
20541250-5	2010	N-glycosylation of the V0a1 subunit, essential for its efficient ER-to-lysosome delivery, requires the selective binding of PS1 holoprotein to the unglycosylated subunit and the Sec61alpha/oligosaccharyltransferase complex.	Nitrogen	0-1	SEC61 translocon subunit alpha 1	Homo sapiens	178-188
23117883-9	2013	N-linked glycosylations of CD44, particularly associated with the variant isoform CD44v6 after CD40L activation, seemed to facilitate hyaluronan recognition by CD44.	Nitrogen	0-1	CD44 molecule (Indian blood group)	Homo sapiens	27-31
23117883-9	2013	N-linked glycosylations of CD44, particularly associated with the variant isoform CD44v6 after CD40L activation, seemed to facilitate hyaluronan recognition by CD44.	Nitrogen	0-1	CD44 molecule (Indian blood group)	Homo sapiens	82-86
23714211-0	2013	N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells.	Nitrogen	0-1	intercellular adhesion molecule 2	Homo sapiens	19-25
23213258-1	2013	A strong positive correlation between vegetation canopy bidirectional reflectance factor (BRF) in the near infrared (NIR) spectral region and foliar mass-based nitrogen concentration (%N) has been reported in some temperate and boreal forests.	Nitrogen	160-168	BRF1 RNA polymerase III transcription initiation factor subunit	Homo sapiens	90-93
23166320-9	2013	Evaluation of the p17 antagonist activity of a panel of biotechnological heparins derived by chemical sulfation of the Escherichia coli K5 polysaccharide revealed that the highly N,O-sulfated derivative prevents the binding of p17 to both heparin and CXCR1, thus inhibiting p17-driven chemotactic migration of human monocytes with an efficiency that is higher than those of heparin and HS.	Nitrogen	179-180	C-X-C motif chemokine receptor 1	Homo sapiens	251-256
20504027-1	2010	Golgi alpha-mannosidase II (GMII), a member of glycoside hydrolase family 38, cleaves two mannosyl residues from GlcNAcMan(5)GlcNAc(2) as part of the N-linked glycosylation pathway.	Nitrogen	116-117	mannosidase alpha class 2A member 1	Homo sapiens	0-26
20504027-1	2010	Golgi alpha-mannosidase II (GMII), a member of glycoside hydrolase family 38, cleaves two mannosyl residues from GlcNAcMan(5)GlcNAc(2) as part of the N-linked glycosylation pathway.	Nitrogen	116-117	mannosidase alpha class 2A member 1	Homo sapiens	28-32
20153800-5	2010	PAF-AH is N-glycosylated prior to secretion which diminishes its association with HDL raising the question of its distribution between the proatherogenic LDL vs the antiatherogenic HDL.	Nitrogen	10-11	phospholipase A2 group VII	Homo sapiens	0-6
23714211-0	2013	N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells.	Nitrogen	0-1	intercellular adhesion molecule 2	Homo sapiens	42-48
20233714-8	2010	Gcn2p activation upon shifting to secondary nitrogen sources is suggested to occur by means of a dual mechanism.	Nitrogen	44-52	serine/threonine-protein kinase GCN2	Saccharomyces cerevisiae S288C	0-5
23392350-7	2013	Treatment of heart lysates with peptide-N-glycosidase F revealed that while giant obscurin-B localizes intracellularly, possessing dual kinase activity, a small obscurin kinase isoform that contains SK1 localizes extracellularly, where it undergoes N-glycosylation.	Nitrogen	40-41	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	Homo sapiens	82-90
20356926-0	2010	N-linked glycosylation is required for optimal proteolytic activation of membrane-bound transcription factor CREB-H.	Nitrogen	0-1	cAMP responsive element binding protein 3 like 3	Homo sapiens	109-115
20356926-4	2010	In this study we characterized N-linked glycosylation of CREB-H in the luminal domain at the C-terminus.	Nitrogen	31-32	cAMP responsive element binding protein 3 like 3	Homo sapiens	57-63
20356926-5	2010	We found that CREB-H is modified at three N-linked glycosylation sites in this region.	Nitrogen	42-43	cAMP responsive element binding protein 3 like 3	Homo sapiens	14-20
20356926-6	2010	Disruption of all three sites by site-directed mutagenesis completely abrogated N-linked glycosylation of CREB-H.	Nitrogen	80-81	cAMP responsive element binding protein 3 like 3	Homo sapiens	106-112
22827340-13	2013	CONCLUSIONS: The decrease in the BMD, BV/TV, and Tb.N is in the same range as what is observed in human drinkers and what is reported with other animal alcohol models (Lieber-DeCarli liquid diet, ethanol in the tap water).	Nitrogen	2-3	nuclear RNA export factor 1	Homo sapiens	211-214
24018687-3	2013	Site-directed mutational analysis of the consensus N-glycosylation sites of the DDRs revealed that mutations of asparagine 213 of DDR2 and asparagine 211 of DDR1, a conserved N-glycosylation site among vertebrate DDRs, inhibited the generation of the high-molecular-mass isoform.	Nitrogen	51-52	discoidin domain receptor tyrosine kinase 2	Homo sapiens	130-134
24018687-3	2013	Site-directed mutational analysis of the consensus N-glycosylation sites of the DDRs revealed that mutations of asparagine 213 of DDR2 and asparagine 211 of DDR1, a conserved N-glycosylation site among vertebrate DDRs, inhibited the generation of the high-molecular-mass isoform.	Nitrogen	175-176	discoidin domain receptor tyrosine kinase 2	Homo sapiens	130-134
20356926-9	2010	Taken together, our findings suggest that N-linked glycosylation is required for full activation of CREB-H through intramembrane proteolysis.	Nitrogen	42-43	cAMP responsive element binding protein 3 like 3	Homo sapiens	100-106
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	77-85	allantoate permease	Saccharomyces cerevisiae S288C	34-38
20005867-4	2010	This feature was associated with increased expression and altered N-linked glycosylation of ATP binding cassette transporters MRP1 and MRP4.	Nitrogen	66-67	ATP binding cassette subfamily C member 4	Homo sapiens	135-139
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	148-156	allantoate permease	Saccharomyces cerevisiae S288C	34-38
23463947-3	2013	Molecular weights can be determined precisely (mass error &lt;= 0.1%) such that high-mass MALDI-MS was able to identify the site for N-linked glycosylation of the eukaryotic multidrug ABC transporter Cdr1p without special purification steps, which is impossible by any other current approach.	Nitrogen	133-134	cerebellar degeneration related protein 1	Homo sapiens	200-205
20181830-8	2010	We show that the putative N-peptide binding area in Sec1p domain 1 is important for Mso1p binding, and that Mso1p can interact with Sso1p and Sso2p.	Nitrogen	26-27	secretory blood group 1, pseudogene	Homo sapiens	52-57
23519668-3	2013	Here, crystal structures of SET7/9 are reported in complexes with two AdoMet analogues, designated DAAM-3 and AAM-1, in which an n-hexylaminoethyl group or an n-hexyl group is attached to the N atom that replaces the S atom of AdoMet, respectively.	Nitrogen	192-193	SET domain containing 7, histone lysine methyltransferase	Homo sapiens	28-34
20089675-3	2010	Inhibition of endogenous TK levels for 10 days by neutralizing TK antibody injection in DOCA-salt rats caused a significant increase in blood urea nitrogen and urinary protein levels, and a decrease in creatinine clearance.	Nitrogen	147-155	kallikrein 1-related peptidase C12	Rattus norvegicus	25-27
20089675-3	2010	Inhibition of endogenous TK levels for 10 days by neutralizing TK antibody injection in DOCA-salt rats caused a significant increase in blood urea nitrogen and urinary protein levels, and a decrease in creatinine clearance.	Nitrogen	147-155	kallikrein 1-related peptidase C12	Rattus norvegicus	63-65
20154027-0	2010	Npr2, yeast homolog of the human tumor suppressor NPRL2, is a target of Grr1 required for adaptation to growth on diverse nitrogen sources.	Nitrogen	122-130	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	0-4
23519668-5	2013	The N atom in the azaalkyl chain of DAAM-3 is located at almost the same position as the N-methyl C atom of the methylated lysine side chain in the substrate-peptide complex structures and stabilizes complex formation by hydrogen bonding to the substrate-binding site residues of SET7/9.	Nitrogen	4-5	SET domain containing 7, histone lysine methyltransferase	Homo sapiens	280-286
20154027-1	2010	Npr2, a putative "nitrogen permease regulator" and homolog of the human tumor suppressor NPRL2, was found to interact with Grr1, the F-box component of the SCF(Grr1) (Skp1-cullin-F-box protein complex containing Grr1) E3 ubiquitin ligase, by mass spectrometry-based multidimensional protein identification technology.	Nitrogen	18-26	KIT ligand	Homo sapiens	156-159
20154027-9	2010	Together, these data indicate that Npr2 is a phosphorylation-dependent target of the SCF(Grr1) E3 ubiquitin ligase that plays a role in cell growth on some nitrogen sources.	Nitrogen	156-164	KIT ligand	Homo sapiens	85-88
23519668-5	2013	The N atom in the azaalkyl chain of DAAM-3 is located at almost the same position as the N-methyl C atom of the methylated lysine side chain in the substrate-peptide complex structures and stabilizes complex formation by hydrogen bonding to the substrate-binding site residues of SET7/9.	Nitrogen	89-90	SET domain containing 7, histone lysine methyltransferase	Homo sapiens	280-286
23423181-2	2013	The activation parameters for nitrogen inversion in a series of azetidines tethered to boronate esters have been quantified by VT-NMR and the measured barriers correlated with data obtained by (11)B NMR, X-ray crystallography and MP2 calculations.	Nitrogen	30-38	tryptase pseudogene 1	Homo sapiens	230-233
20338479-6	2010	However, for cells with an N-glycosylation site mutant of integrin beta1 located on the I-like domain (Mu3), these effects were dramatically inhibited.	Nitrogen	27-28	integrin subunit beta 1	Homo sapiens	58-72
23402879-1	2013	The known DNMT inhibitor SGI-1027 4 has been synthesized using as key steps Pd-catalyzed Ar-N bond formation reactions performed in a sequential or convergent manner.	Nitrogen	11-12	semenogelin 1	Homo sapiens	25-28
20209559-1	2010	Golgi alpha-mannosidase II (GMII) is a key enzyme in the N-glycosylation pathway and is a potential target for cancer chemotherapy.	Nitrogen	57-58	alpha-Mannosidase class II a	Drosophila melanogaster	0-26
23375447-4	2013	As a rule, the introduction of substituents containing nitrogen atoms at the C-9 position led to a considerable decrease or loss of antiparkinsonian activity.	Nitrogen	55-63	complement component 9	Mus musculus	77-80
20142501-9	2010	Multiple Ygp1 N-glycosylation sites bearing GlcNAc, isotopically labeled GlcNAc, or GlcNAz were identified; these modifications were dependent on the supplement added to the culture medium.	Nitrogen	14-15	Ygp1p	Saccharomyces cerevisiae S288C	9-13
20083147-1	2010	Plant-specific N-glycosylation, such as the introduction of core alpha1,3-fucose and beta1,2-xylose residues, is a major obstacle to the utilization of plant cell- or plant-derived recombinant therapeutic proteins.	Nitrogen	15-16	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	85-92
23301562-2	2013	A regiospecific synthesis of multifunctional pyrazoleshas been developed from a cascade process triggered by Rh(II)-catalyzed dinitrogen extrusion from enol diazoacetates with vinylogous nucleophilic addition followed by Lewis acid catalyzed cyclization and aromatization.	Nitrogen	126-136	Rh blood group D antigen	Homo sapiens	109-116
19854849-5	2010	RESULTS: Preferential inactivation of the mutant Col4a5 gene improved survival and surrogate outcome measures of urine protein and plasma urea nitrogen.	Nitrogen	143-151	collagen, type IV, alpha 5	Mus musculus	49-55
20121272-12	2010	The increase of n(s)(BSA) by an increase in X(Fe) was explained by elongation of mean particle length along with the production of surface hydroxo ions, such as Fe(OH)2+ or Fe(OH)2+, to induce the hydrogen bond between the Fe(III)-substituted Hap surface and BSA molecules, though the number of original C sites established by Ca(II) atoms was reduced.	Nitrogen	16-20	carbonic anhydrase 2	Homo sapiens	327-333
20007158-4	2010	Links between stress and nitrogen / amino acid signalling are also described, including the roles of a protein kinase called general control non-derepressible (GCN)-2 in regulating protein synthesis through phosphorylation of the alpha-subunit of translation initiation factor-2 (eIF2alpha) in response not only to decreases in amino acid levels but also to a range of stresses.	Nitrogen	25-33	eukaryotic translation initiation factor 2 alpha kinase 4	Homo sapiens	125-166
20007158-4	2010	Links between stress and nitrogen / amino acid signalling are also described, including the roles of a protein kinase called general control non-derepressible (GCN)-2 in regulating protein synthesis through phosphorylation of the alpha-subunit of translation initiation factor-2 (eIF2alpha) in response not only to decreases in amino acid levels but also to a range of stresses.	Nitrogen	25-33	eukaryotic translation initiation factor 2A	Homo sapiens	280-289
23250752-0	2013	N-glycosylation-dependent control of functional expression of background potassium channels K2P3.1 and K2P9.1.	Nitrogen	0-1	potassium two pore domain channel subfamily K member 3	Homo sapiens	92-98
19800402-7	2010	The full-length hFSHR and the membrane-anchored ECD were then each engineered to introduce a consensus site for N-linked glycosylation at residue 110.	Nitrogen	112-113	follicle stimulating hormone receptor	Homo sapiens	16-21
23073781-4	2013	The derived amino acid sequence of NDUFS4 is well conserved compared with NDUFS4 of various species with higher degree of sequence similarity with other mammalian (86.3-92.6 %) than amphibian, aves, and fishes (70.2-81.1 %), and contains one N-linked glycosylation site, one O-linked glycosylation site, seven Ser phosphorylation sites and five Thr phosphorylation sites.	Nitrogen	35-36	NADH:ubiquinone oxidoreductase subunit S4	Homo sapiens	74-80
20025627-7	2010	The results obtained, demonstrating the presence of N/OFQ in some alpha-MSH- and in many orexin-containing neurones, suggest a functional relationship between these neuropeptides and N/OFQ in the control of feeding behaviour and body weight.	Nitrogen	52-53	proopiomelanocortin	Rattus norvegicus	66-75
20002318-1	2010	Experimental evidence demonstrates a higher efficiency of water and nitrogen use in C(4) compared with C(3) plants, which is hypothesized to drive differences in biomass allocation between C(3) and C(4) species.	Nitrogen	68-76	complement C3	Homo sapiens	189-193
19940140-9	2010	Moreover, we demonstrated that NDST1 was able to partially sulfate exogenous substrate in the absence of NDST2 but not vice versa, suggesting that both isoenzymes do not have redundant activities but do have rather complementary activities in making N-sulfated sequences with CyPB-binding properties.	Nitrogen	31-32	N-deacetylase and N-sulfotransferase 2	Homo sapiens	105-110
23223232-1	2013	The GATA family transcription activator, Gln3 responds to the nitrogen requirements and environmental resources of the cell.	Nitrogen	62-70	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	4-8
19940140-9	2010	Moreover, we demonstrated that NDST1 was able to partially sulfate exogenous substrate in the absence of NDST2 but not vice versa, suggesting that both isoenzymes do not have redundant activities but do have rather complementary activities in making N-sulfated sequences with CyPB-binding properties.	Nitrogen	31-32	peptidylprolyl isomerase B	Homo sapiens	276-280
23005037-9	2013	The present study reveals the important role of N-glycosylation of CD147 in its biological function and implied that targeting aberrant beta1,6-branching of N-glycans on CD147 would be valuable for the development of novel therapeutic modalities against carcinoma.	Nitrogen	48-49	basigin (Ok blood group)	Homo sapiens	67-72
20082270-4	2010	Acetaldehyde induced the expression of a PSO2-lacZ reporter construct that is specifically inducible by bi- or poly-functional mutagens, e.g., nitrogen mustard and photo-activated psoralens.	Nitrogen	143-151	DNA cross-link repair protein PSO2	Saccharomyces cerevisiae S288C	41-45
23005037-9	2013	The present study reveals the important role of N-glycosylation of CD147 in its biological function and implied that targeting aberrant beta1,6-branching of N-glycans on CD147 would be valuable for the development of novel therapeutic modalities against carcinoma.	Nitrogen	48-49	basigin (Ok blood group)	Homo sapiens	170-175
23085985-6	2013	The Ag2 ion is coordinated to the N61 oxime nitrogens, a monodentate and a (O,O)-bridging nitrato/perchlorato or two monodentate O-trifluoromethylsulfonato anions.	Nitrogen	44-53	anterior gradient 2, protein disulphide isomerase family member	Homo sapiens	4-7
20448301-5	2010	The XPS results showed that the N2 and O2 plasma pre-treatment produced nitride and oxide on the substrate surfaces, such as TiO2, TiO, Fe2O3, CrN and TiNO.	Nitrogen	32-34	mex-3 RNA binding family member D	Homo sapiens	151-155
23577216-9	2013	In addition to inorganic N compounds that might play a key role in shaping the anammox microbiota, organic carbon, organic nitrogen, sulfate, sulfide and metals all showed the potentials to participate in the anammox process, releasing the strict dependence of the anammox bacteria upon the direct availability of inorganic N nutrients that might be limiting in certain areas of the Bohai Sea.	Nitrogen	25-26	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	389-392
20722616-3	2010	The simple bisphosphonates, clodronate, etidronate and tiludronate, are intracellularly metabolised to cytotoxic ATP analogues, while the more potent, nitrogen-containing bisphosphonates act by inhibiting the enzyme FPP synthase, thereby preventing the prenylation of small GTPases that are necessary for the normal function and survival of osteoclasts.	Nitrogen	151-159	farnesyl diphosphate synthase	Homo sapiens	216-228
23319116-8	2013	Large-scale production of highly pure N-myristoylated Arf6 could be achieved, which was fully functional for liposome-binding and EFA6-stimulated nucleotide exchange assays.	Nitrogen	38-39	ADP ribosylation factor 6	Homo sapiens	54-58
19769332-4	2009	Systematic replacement of each of the unfused carbon atoms in the phenyl ring of the indole moiety by a nitrogen atom provided four different azaindole derivatives that displayed a clear SAR for antiviral activity and all of which displayed marked improvements in pharmaceutical properties.	Nitrogen	104-112	sarcosine dehydrogenase	Homo sapiens	187-190
23194315-7	2012	G3(MP2) calculations show that the most energetically favored site of deprotonation is an amide nitrogen, with the central amide being generally preferred.	Nitrogen	96-104	tryptase pseudogene 1	Homo sapiens	3-6
19699819-4	2009	Nitrogen-containing bisphosphonates (N-BPs), including zoledronic acid (ZOL), act by inhibiting farnesyl pyrophosphate synthase (FPPS).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	96-127
19699819-4	2009	Nitrogen-containing bisphosphonates (N-BPs), including zoledronic acid (ZOL), act by inhibiting farnesyl pyrophosphate synthase (FPPS).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	129-133
22924387-0	2012	The mitochondrial Amidoxime Reducing Component (mARC) is involved in detoxification of N-hydroxylated base analogues.	Nitrogen	87-88	activity regulated cytoskeletal-associated protein	Mus musculus	48-52
24175472-3	2013	They consist, from one side, in activating of the constitutive de novo biosynthesis of nitric oxide by cNOS, from other side, in suppression of inducible nitric oxide de novo synthesis by iNOS in such way to prevent the formation of toxic peroxynitrite by co-operation of surplus nitric oxide with superoxide anion, thereby limits the generation of toxic active forms of nitrogen (*NO2) and oxygen (*OH).	Nitrogen	371-379	nitric oxide synthase 3	Canis lupus familiaris	103-107
22924387-4	2012	Here, we demonstrate the reductive detoxification of toxic and mutagenic N-hydroxylated nucleobases and their corresponding nucleosides by the mammalian mARC-containing enzyme system.	Nitrogen	73-74	activity regulated cytoskeletal-associated protein	Mus musculus	153-157
22924387-8	2012	On the basis of the high specific activities with N-hydroxylated base analogues relative to other N-hydroxylated substrates, our data suggest that mARC proteins might be involved in protecting cellular DNA from misincorporation of toxic N-hydroxylated base analogues during replication by converting them to the correct purine or pyrimidine bases, respectively.	Nitrogen	50-51	activity regulated cytoskeletal-associated protein	Mus musculus	147-151
23533771-4	2013	In addition, the nitrogen-containing BPs (N-BPs), second-generation BPs, act by inhibiting farnesyl diphosphate (FPP) synthase, a key enzyme of the mevalonate pathway.	Nitrogen	17-25	farnesyl diphosphate synthase	Homo sapiens	91-126
22924387-8	2012	On the basis of the high specific activities with N-hydroxylated base analogues relative to other N-hydroxylated substrates, our data suggest that mARC proteins might be involved in protecting cellular DNA from misincorporation of toxic N-hydroxylated base analogues during replication by converting them to the correct purine or pyrimidine bases, respectively.	Nitrogen	98-99	activity regulated cytoskeletal-associated protein	Mus musculus	147-151
22820730-0	2013	Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).	Nitrogen	26-34	cyclin-dependent kinase 2	Mus musculus	167-171
22820730-0	2013	Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).	Nitrogen	26-34	FMS-like tyrosine kinase 3	Mus musculus	201-227
22924387-8	2012	On the basis of the high specific activities with N-hydroxylated base analogues relative to other N-hydroxylated substrates, our data suggest that mARC proteins might be involved in protecting cellular DNA from misincorporation of toxic N-hydroxylated base analogues during replication by converting them to the correct purine or pyrimidine bases, respectively.	Nitrogen	98-99	activity regulated cytoskeletal-associated protein	Mus musculus	147-151
22820730-0	2013	Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3).	Nitrogen	26-34	FMS-like tyrosine kinase 3	Mus musculus	229-233
23012370-2	2012	Elastin is a common insoluble protein that is abundant in marine vertebrates, and for this reason its degradation is important for the recycling of marine nitrogen.	Nitrogen	155-163	elastin	Bos taurus	0-7
24260614-6	2013	However, when exposed to elevated oxidative stress, additional pathways independent of these three sensor proteins are activated to destroy cyclin C. In addition, N-glycosylation is important for Mtl1 function as mutating the receptor residue (Asn42) or an enzyme required for synthesis of N-acetylglucosamine (Gfa1) reduces sensor activity.	Nitrogen	163-164	Mtl1p	Saccharomyces cerevisiae S288C	196-200
23505583-5	2013	METHODOLOGY/PRINCIPAL FINDINGS: In a preliminary study of expressing original CTB in transgenic Nicotiana benthamiana, the protein was N-glycosylated with plant-specific glycans.	Nitrogen	15-16	phosphate cytidylyltransferase 1, choline, beta isoform	Mus musculus	78-81
23062821-5	2012	Tail-tail dimer 9a was shown to be active in a breast and in an ovary tumor model, highlighting the potential of dimeric Smac mimetics/IAP inhibitors based on the N-AVPI-like 4-substituted 1-aza-2-oxobicyclo[5.3.0]decane scaffold as potential antineoplastic agents.	Nitrogen	163-165	diablo IAP-binding mitochondrial protein	Homo sapiens	121-125
23069765-0	2013	Unexpected mucin-type O-glycosylation and host-specific N-glycosylation of human recombinant interleukin-17A expressed in a human kidney cell line.	Nitrogen	56-57	interleukin 17A	Homo sapiens	93-108
23069765-2	2013	Its polypeptide monomer contains one canonical N-glycosylation site at Asn68, and human recombinant IL-17A was partly N-glycosylated when expressed in human kidney (HEK293) cells as a fusion protein with a melittin signal sequence and an N-terminal hexahistidine tag.	Nitrogen	118-119	interleukin 17A	Homo sapiens	100-106
22968639-6	2012	Significant interactions were observed between the Lepr genotype and chromosome 1 QTL for six renal traits: urine volume, UAE at 10 and 15 wk, ACR, right kidney weight, and plasma urea nitrogen.	Nitrogen	185-193	leptin receptor	Rattus norvegicus	51-55
23069765-4	2013	The mass spectrum of IL-17A monomer also included peaks shifted by +948 Da from the respective masses of unglycosylated and N-glycosylated polypeptides.	Nitrogen	124-125	interleukin 17A	Homo sapiens	21-27
23069765-7	2013	Therefore, the kidney host cell line not only imposed its characteristic pattern of N-glycosylation on recombinant IL-17A but additionally created an O-glycosylation not known to be present in the T cell-derived cytokine.	Nitrogen	84-85	interleukin 17A	Homo sapiens	115-121
22989268-0	2012	Pyramidalization of the glycosidic nitrogen provides the way for efficient cleavage of the N-glycosidic bond of 8-OxoG with the hOGG1 DNA repair protein.	Nitrogen	35-43	8-oxoguanine DNA glycosylase	Homo sapiens	128-133
22989268-2	2012	The reaction scheme suggests direct proton addition to the glycosidic nitrogen N9 of oxoG from the Nepsilon-ammonium of Lys249 residue of hOGG1 that is enabled owing to the N9 pyramidal geometry.	Nitrogen	70-78	8-oxoguanine DNA glycosylase	Homo sapiens	138-143
23125776-1	2012	A binary mixture of benzyl-amine and hexa-noic acid has been reacted to form the title salt, C(7)H(10)N(+) C(6)H(11)O(2) (-).	Nitrogen	102-103	hexosaminidase subunit alpha	Homo sapiens	37-41
22750665-5	2012	Rats maintained on the n-3 deficient diet exhibited significantly lower liver and erythrocyte LCn-3 fatty acid levels, and associated elevations in LCn-6/LCn-3 ratio.	Nitrogen	8-9	lipocalin 6	Rattus norvegicus	148-153
22946557-8	2012	and indicates that enthalpy and entropy may both contribute to the stabilization of human CD2 by N-glycosylation.	Nitrogen	97-98	CD2 molecule	Homo sapiens	90-93
22998279-8	2012	Of all methods investigated (HF, DFT/PBE, DFT/B3LYP, MP2), only MP2 and DFT/B3LYP were able to describe the adsorption of N(2) on the rutile surface properly.	Nitrogen	122-126	tryptase pseudogene 1	Homo sapiens	64-67
22787146-4	2012	To assess its roles, we first expressed recombinant WBSCR17 in COS7 cells and demonstrated that it was N-glycosylated and localized mainly in the Golgi apparatus, as is the case for the other GalNAc-Ts.	Nitrogen	103-104	polypeptide N-acetylgalactosaminyltransferase 17	Homo sapiens	52-59
22837063-5	2012	DFT calculations on [Fe(IV)(O)(bpmen)] ions showed that the experimentally observed preference for oxidative N-dealkylation versus dehydrogenation of the diaminoethane linker for the hexa- and pentacoordinate ions, respectively, is dictated by the proximity of the target C-H bond to the oxoiron(IV) moiety and the reactive spin state.	Nitrogen	109-110	hexosaminidase subunit alpha	Homo sapiens	183-187
22402397-0	2012	Evidence for the direct oxidation of organic nitrogen to N2 gas in the Arabian Sea.	Nitrogen	45-53	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	79-82
23131341-4	2012	SYK-134 (7a) and SYK-135 (8a) with N-cyclopropylmethyl substituent and cap structures showed selectivities for the kappa opioid receptor.	Nitrogen	35-36	opioid receptor kappa 1	Homo sapiens	115-136
23249007-2	2012	In the S(0) state of TRA(H(2)O)(1), a water molecule is hydrogen-bonded to the N atom of the amino group of a flexible ethylamine side chain [T. S. Zwier, J. Phys.	Nitrogen	79-80	T cell receptor alpha locus	Homo sapiens	21-24
22959971-3	2012	Based on the structure of a yeast polyamine oxidase, Saccharomyces cerevisiae Fms1, this residue has been proposed to hydrogen bond to the reactive nitrogen in the polyamine substrate.	Nitrogen	148-156	polyamine oxidase	Saccharomyces cerevisiae S288C	34-51
22959971-3	2012	Based on the structure of a yeast polyamine oxidase, Saccharomyces cerevisiae Fms1, this residue has been proposed to hydrogen bond to the reactive nitrogen in the polyamine substrate.	Nitrogen	148-156	polyamine oxidase	Saccharomyces cerevisiae S288C	78-82
23073695-5	2012	Overexpression of PIF5 was sufficient to suppress photosynthetic rate, enhance response to elevated carbon dioxide, and prolong seedling survival in nitrogen-limiting conditions.	Nitrogen	149-157	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	18-22
23106489-5	2012	However, the intermolecular bond bundles in crystalline RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) change from C-N trigger linkages in the gas phase to N-N trigger linkages in the solid state.	Nitrogen	116-117	radixin	Homo sapiens	56-59
23106489-5	2012	However, the intermolecular bond bundles in crystalline RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) change from C-N trigger linkages in the gas phase to N-N trigger linkages in the solid state.	Nitrogen	155-158	radixin	Homo sapiens	56-59
26605629-6	2012	First-principles calculations suggest that EPR spin Hamiltonian parameters including the nitroxide nitrogen hyperfine coupling tensor A(N) and electronic g tensor suffer noticeable changes upon complexation with the protein.	Nitrogen	99-107	spindlin 1	Homo sapiens	47-51
22665675-26	2012	Feeding TS2 reduced NH(3) emission per unit of N consumed by 30% compared with C2 (P &lt; 0.01).	Nitrogen	20-21	sex determination protein tasselseed-2	Zea mays	8-11
23054359-3	2012	Vitrification has successfully been applied to ovarian tissue using different carriers for tissue exposure to the liquid nitrogen (LN2).	Nitrogen	121-129	NZ lupus nephritis 2	Mus musculus	131-134
22966204-7	2012	We here show that on a poor nitrogen source, the Bul adaptors are phosphorylated in an Npr1-dependent manner and bound to 14-3-3 proteins that protect Gap1 against downregulation.	Nitrogen	28-36	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	87-91
22984264-7	2012	In this report, we investigated whether the N-myristoylation and Ca(2+)-binding domains of CHP3 are important elements for regulating NHE1.	Nitrogen	44-45	tescalcin	Homo sapiens	91-95
22990609-0	2012	Roughening of hcp metal surfaces induced by nitrogen adsorption.	Nitrogen	44-52	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	14-17
22948147-5	2012	In this study, we find that afadin, a component of N-cadherin beta-catenin alpha-N-catenin adhesion complexes, is required for the maintenance of established dendritic arborization and synapse number.	Nitrogen	80-82	afadin, adherens junction formation factor	Homo sapiens	28-34
23009692-2	2012	Compound {Fe(MeOH)(2)[Pd(SCN)(4)]} pz (1a) is a two-dimensional coordination polymer where the Fe(II) ions are equatorially coordinated by the nitrogen atoms of four [Pd(SCN)(4)](2-) anions, each of which connects four Fe(II) ions, forming corrugated layers {Fe[Pd(SCN)(4)]}( ).	Nitrogen	143-151	sorcin	Homo sapiens	25-28
22761399-10	2012	Finally, the studies on KRAS-regulated N-glycoproteins revealed structural alterations in the core N-glycans of SEMA4B in KRAS-activated human bronchial epithelial cells and functional role of N-glycosylation of TIMP-1 in the regulation of lung adenocarcinoma A549 cell invasion.	Nitrogen	39-40	KRAS proto-oncogene, GTPase	Homo sapiens	24-28
22761399-10	2012	Finally, the studies on KRAS-regulated N-glycoproteins revealed structural alterations in the core N-glycans of SEMA4B in KRAS-activated human bronchial epithelial cells and functional role of N-glycosylation of TIMP-1 in the regulation of lung adenocarcinoma A549 cell invasion.	Nitrogen	39-40	KRAS proto-oncogene, GTPase	Homo sapiens	122-126
22761399-11	2012	Together, our study represents the largest proteome and N-glycoproteome data sets for HBECs, which we used to identify several novel potential targets of activated KRAS that may provide insights into KRAS-induced adenocarcinoma and have implications for both lung cancer therapy and diagnosis.	Nitrogen	56-57	KRAS proto-oncogene, GTPase	Homo sapiens	164-168
22761399-11	2012	Together, our study represents the largest proteome and N-glycoproteome data sets for HBECs, which we used to identify several novel potential targets of activated KRAS that may provide insights into KRAS-induced adenocarcinoma and have implications for both lung cancer therapy and diagnosis.	Nitrogen	56-57	KRAS proto-oncogene, GTPase	Homo sapiens	200-204
22921759-2	2012	Also influenza viruses are recognized by SP-D and their susceptibility to neutralization by SP-D is dependent on the number of N-linked glycosylation sites in the hemagglutinin in particular.	Nitrogen	127-128	surfactant protein D	Homo sapiens	92-96
22884353-1	2012	Nitrogen-containing bisphosphonates (N-BPs) are potent active site inhibitors of the human farnesyl pyrophosphate synthase (hFPPS) and valuable human therapeutics for the treatment of bone-related malignancies.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	91-122
22884353-1	2012	Nitrogen-containing bisphosphonates (N-BPs) are potent active site inhibitors of the human farnesyl pyrophosphate synthase (hFPPS) and valuable human therapeutics for the treatment of bone-related malignancies.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	124-129
19681908-2	2009	Here we report that Campylobacter jejuni proteins that are modified by the N-linked glycosylation machinery encoded by the pgl locus bind the human Macrophage Galactose-type lectin (MGL).	Nitrogen	75-76	C-type lectin domain containing 10A	Homo sapiens	148-180
19681908-2	2009	Here we report that Campylobacter jejuni proteins that are modified by the N-linked glycosylation machinery encoded by the pgl locus bind the human Macrophage Galactose-type lectin (MGL).	Nitrogen	75-76	C-type lectin domain containing 10A	Homo sapiens	182-185
19681908-8	2009	Collectively, our results provide evidence that both N-linked glycoproteins and distinct lipooligosaccharide glycoforms of C. jejuni are ligands for the human C-type lectin MGL and that the C. jejuni N-glycosylation machinery can be exploited to target recombinant bacteria to MGL-expressing eukaryotic cells.	Nitrogen	53-54	C-type lectin domain containing 10A	Homo sapiens	173-176
19479373-2	2009	Cell surface-bound glypican-1 becomes internalized and recycles via endosomes, where the heparan sulphate chains undergo nitric oxide and copper dependent autocleavage at N-unsubstituted glucosamines, back to the Golgi.	Nitrogen	171-172	glypican 1	Homo sapiens	19-29
19799387-11	2009	Nitrogen substitution enhances this torsional induced nonradiative process and it follows the order HPBI &lt; HPIP-b &lt; HPIP-c &lt; HPP.	Nitrogen	0-8	PBX homeobox interacting protein 1	Homo sapiens	110-114
19799387-11	2009	Nitrogen substitution enhances this torsional induced nonradiative process and it follows the order HPBI &lt; HPIP-b &lt; HPIP-c &lt; HPP.	Nitrogen	0-8	PBX homeobox interacting protein 1	Homo sapiens	122-126
19886837-4	2009	Major V1 Env sequence expansion, variation by a duplication event, and cumulative addition of cysteine residues and potential N-glycosylation sites over time may contribute to escape from antibody pressure directed to Env receptor domains by changing the exposure of neutralization-sensitive epitopes.	Nitrogen	126-127	endogenous retrovirus group K member 20	Homo sapiens	218-221
19714320-6	2009	The relation of boron and nitrogen changes with the character of the auxiliary gas: cB/cN approximately = 4:3 (for H2 and He) and cB/cN approximately = 1 (for N2 or NH3).	Nitrogen	26-34	relaxin 2	Homo sapiens	115-124
20716918-4	2009	Significantly lower levels of n-6/n-3 FA ratio were observed in serum, muscle and liver of Fat-1 mice fed AL or CR as compared to that of WT mice fed AL or CR.	Nitrogen	3-4	FAT atypical cadherin 1	Mus musculus	91-96
19683424-0	2009	A glucose biosensor based on direct electrochemistry of glucose oxidase immobilized on nitrogen-doped carbon nanotubes.	Nitrogen	87-95	hydroxyacid oxidase 1	Homo sapiens	56-71
19683424-1	2009	A novel biosensor for glucose was prepared by immobilizing glucose oxidase (GOx) on nitrogen-doped carbon nanotubes (CNx-MWNTs) modified electrode.	Nitrogen	84-92	hydroxyacid oxidase 1	Homo sapiens	59-74
19683424-1	2009	A novel biosensor for glucose was prepared by immobilizing glucose oxidase (GOx) on nitrogen-doped carbon nanotubes (CNx-MWNTs) modified electrode.	Nitrogen	84-92	hydroxyacid oxidase 1	Homo sapiens	76-79
19774287-3	2009	In this study, the role of the interplay between solvent water and nitrogen (MEA)-carbon (CO2) bond formation is discussed based on the molecular theory using RISM-SCF-SEDD, which is the hybrid method of quantum chemistry of solute and statistical mechanics of solvent.	Nitrogen	67-75	KIT ligand	Homo sapiens	164-167
19754436-3	2009	Lipid droplets grow in size by fusion, which is dependent on dynein and the transfer on microtubules, and is catalysed by the SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) proteins SNAP-23 (23 kDa synaptosome-associated protein), syntaxin-5 and VAMP-4 (vesicle-associated protein 4).	Nitrogen	127-128	synaptosome associated protein 23	Homo sapiens	221-267
19754436-3	2009	Lipid droplets grow in size by fusion, which is dependent on dynein and the transfer on microtubules, and is catalysed by the SNARE (soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptor) proteins SNAP-23 (23 kDa synaptosome-associated protein), syntaxin-5 and VAMP-4 (vesicle-associated protein 4).	Nitrogen	127-128	syntaxin 5	Homo sapiens	270-280
19778448-6	2009	Cells transfected with GPC retained surface membrane-associated expression of GP1 as determined by immunofluorescence assay, in addition to secreting the glycoprotein.Secreted GP1 derived from GPC expression has a higher content of high mannose N-linked glycosylation than sGP1 expressed independently from the GP2 portion of the protein.	Nitrogen	245-246	glycophorin C (Gerbich blood group)	Homo sapiens	23-26
19778448-6	2009	Cells transfected with GPC retained surface membrane-associated expression of GP1 as determined by immunofluorescence assay, in addition to secreting the glycoprotein.Secreted GP1 derived from GPC expression has a higher content of high mannose N-linked glycosylation than sGP1 expressed independently from the GP2 portion of the protein.	Nitrogen	245-246	GTP binding protein 1	Homo sapiens	176-179
19778448-6	2009	Cells transfected with GPC retained surface membrane-associated expression of GP1 as determined by immunofluorescence assay, in addition to secreting the glycoprotein.Secreted GP1 derived from GPC expression has a higher content of high mannose N-linked glycosylation than sGP1 expressed independently from the GP2 portion of the protein.	Nitrogen	245-246	glycophorin C (Gerbich blood group)	Homo sapiens	193-196
19692640-10	2009	The modifications of secreted ECP were partly explained by differences in N-linked glycosylations.	Nitrogen	74-75	ribonuclease A family member 3	Homo sapiens	30-33
19409451-8	2009	Functional channels were not formed following mutation of a single amino acid within a conserved protein motif recently shown to be N-glycosylated in rodent Panx1.	Nitrogen	132-133	pannexin 1a	Danio rerio	157-162
19737401-5	2009	We found that BST-2 is modified by N-linked glycosylation at two sites in the extracellular domain.	Nitrogen	35-36	bone marrow stromal cell antigen 2	Homo sapiens	14-19
19574222-4	2009	However, Put3p also responds to other lower quality nitrogen sources.	Nitrogen	52-60	Put3p	Saccharomyces cerevisiae S288C	9-14
19574222-5	2009	As nitrogen quality decreases, Put3p exhibits an increase in phosphorylation concurrent with an increase in PUT gene expression.	Nitrogen	3-11	Put3p	Saccharomyces cerevisiae S288C	31-36
19553107-3	2009	SAR exploration around the nitrogen of the aminoethyl appendage chain of 1 led to compounds that displayed low nanomolar activity in a PARP1 enzymatic assay.	Nitrogen	27-35	sarcosine dehydrogenase	Homo sapiens	0-3
19390997-7	2009	Moreover, urine NGAL was found to be correlated positively with cystatin C, urea nitrogen, and serum creatinine (SCr), and inversely with glomerular filtration rate (GFR), while serum NGAL correlated negatively with cystatin C and urea nitrogen, at both baseline and follow-up levels.	Nitrogen	81-89	lipocalin 2	Homo sapiens	16-20
19578754-0	2009	CBP-mediated post-translational N-glycosylation of BRCA2.	Nitrogen	32-33	BRCA2 DNA repair associated	Homo sapiens	51-56
19578754-4	2009	Digestion with peptide N-glycosidase F indicates that the glycosylation of BRCA2 is N-linked.	Nitrogen	23-24	BRCA2 DNA repair associated	Homo sapiens	75-80
19392706-2	2009	With the aim of understanding the importance of nitrogen (N) uptake into developing embryos, we analysed two mutants of AAP1 (At1g58360), an amino acid transporter that was localized to Arabidopsis embryos.	Nitrogen	58-59	amino acid permease 1	Arabidopsis thaliana	120-124
19392706-3	2009	In mature and desiccated aap1 seeds the total N and carbon content was reduced while the total free amino acid levels were strongly increased.	Nitrogen	46-47	amino acid permease 1	Arabidopsis thaliana	25-29
19135780-1	2009	This paper reports the suitability of a novel nitrogen rich compound, guanidinium-5-aminotetrazolate for RDX-based high-energy gun propellant formulations in respect of flame temperature as well as the burning rate characteristics.	Nitrogen	46-54	radixin	Homo sapiens	105-108
21583633-1	2009	In the title compound, C(8)H(7)Br(2)NO, the conformation of the N-H bond is anti to both the carbonyl and C-Br bonds in the side chain.	Nitrogen	36-37	carbonyl reductase 1	Homo sapiens	106-110
19549906-0	2009	Overexpression of DPAGT1 leads to aberrant N-glycosylation of E-cadherin and cellular discohesion in oral cancer.	Nitrogen	43-44	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	18-24
19549906-5	2009	We show that dense cultures of human salivary epidermoid carcinoma A253 cells exhibited elevated expression of DPAGT1, the gene that initiates protein N-glycosylation.	Nitrogen	151-152	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	111-117
19549906-11	2009	Our studies show for the first time that DPAGT1 is an upstream regulator of E-cadherin N-glycosylation status and adherens junction composition and suggest that dysregulation of DPAGT1 causes disturbances in intercellular adhesion in oral cancer.	Nitrogen	87-88	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	41-47
22743139-10	2012	Urinary CNP excretion was negatively correlated with urinary protein concentration, blood urea nitrogen and creatinine, while positively correlated with albumin.	Nitrogen	95-103	natriuretic peptide C	Rattus norvegicus	8-11
22683714-5	2012	The highest C-2 activity was attributed to the presence of non-bonded nitrogen interactions which were absent in C-1 and blocked with butoxycarbonyl (BOC group) in C-3.	Nitrogen	70-78	complement C3	Rattus norvegicus	164-167
22947863-1	2012	The membrane-active antimicrobial peptide PGLa from Xenopus laevis is known from solid-state (2)H-, (15)N-, and (19)F-NMR spectroscopy to occupy two distinct alpha-helical surface adsorbed states in membranes: a surface-bound S-state with a tilt angle of ~95  at low peptide/lipid molar ratio (P/L = 1:200), and an obliquely tilted T-state with a tilt angle of 127  at higher peptide concentration (P/L = 1:50).	Nitrogen	104-105	prepro-PGLa S homeolog	Xenopus laevis	42-46
22905002-1	2012	In the title compound, C(12)H(9)ClN(2)O(4)S, the N-H bond in the -SO(2)-NH- segment is syn to both the ortho-nitro group in the sulfonyl-benzene ring and the ortho-Cl atom in the aniline ring.	Nitrogen	34-35	synemin	Homo sapiens	87-90
21938481-6	2012	Treatment of differentiating cells with alendronate or pamidronate, nitrogen-containing BPs increase the expression of OPG, which suppresses osteoclastogenesis, whereas it decreases the expression of M-CSF, which enhances preosteoclast formation.	Nitrogen	68-76	basic transcription factor 3 pseudogene 11	Homo sapiens	119-122
22670778-7	2012	In the pre-eclamptic group, plasma ficolin-2 levels showed a significant positive correlation with serum placental growth factor (PlGF) concentrations and significant inverse correlations with serum levels of soluble fms-like tyrosine kinase-1 (sFlt-1), blood urea nitrogen and creatinine, serum lactate dehydrogenase activities, as well as with plasma VWF:antigen, fibronectin and cell-free fetal DNA concentrations.	Nitrogen	265-273	ficolin 2	Homo sapiens	35-44
22511785-6	2012	Mutation of predicted N-glycosylation sites on SIRPalpha indicates that Sp-D binding is dependent on interactions with specific N-glycosylated residues on the membrane-proximal D3 domain of SIRPalpha.	Nitrogen	22-23	surfactant protein D	Homo sapiens	72-76
22511785-6	2012	Mutation of predicted N-glycosylation sites on SIRPalpha indicates that Sp-D binding is dependent on interactions with specific N-glycosylated residues on the membrane-proximal D3 domain of SIRPalpha.	Nitrogen	128-129	surfactant protein D	Homo sapiens	72-76
22937648-6	2012	In the 0-42 days after anthesis under split nitrogen application, the glutamine synthetase, glutamate synthase, and glutamate dehydrogenase activities of DH661 and ZD958 were averagely increased by 32.6%, 47.1% and 50.4%, and 14.5%, 61.8% and 25.6%, and the superoxide dismutase and catalase activities were increased by 22.	Nitrogen	44-52	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	92-139
22474297-0	2012	Resolving nitrogen-15 and proton chemical shifts for mobile segments of elastin with two-dimensional NMR spectroscopy.	Nitrogen	10-18	elastin	Homo sapiens	72-79
19549906-11	2009	Our studies show for the first time that DPAGT1 is an upstream regulator of E-cadherin N-glycosylation status and adherens junction composition and suggest that dysregulation of DPAGT1 causes disturbances in intercellular adhesion in oral cancer.	Nitrogen	87-88	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	178-184
19532984-1	2009	A series of 2beta-carbomethoxy-3beta-phenyl tropanes with conformationally constrained nitrogen substituents were synthesized as potential selective dopamine transporter ligands.	Nitrogen	87-95	solute carrier family 6 member 3	Homo sapiens	149-169
19413349-0	2009	N-linked deglycosylated melanopsin retains its responsiveness to light.	Nitrogen	0-1	opsin 4	Rattus norvegicus	24-34
19413349-2	2009	Rat melanopsin contains two potential sites (Asn31 and Asn35) for N-linked glycosylation in the N-terminal extracellular part.	Nitrogen	66-67	opsin 4	Rattus norvegicus	4-14
19413349-5	2009	Removal of N-linked glycosylation by tunicamycin or PNGase F changed the 62 kDa band to a 55 kDa band, while the 49 kDa band corresponding to the core melanopsin protein was unaffected.	Nitrogen	11-12	opsin 4	Rattus norvegicus	151-161
22402397-0	2012	Evidence for the direct oxidation of organic nitrogen to N2 gas in the Arabian Sea.	Nitrogen	57-59	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	79-82
19413349-6	2009	Likewise, mutation of the two extracellular N-linked glycosylation sites gave a melanopsin size comparable to that of PNGase F or tunicamycin treatment (55 kDa).	Nitrogen	44-45	opsin 4	Rattus norvegicus	80-90
19413349-9	2009	In conclusion, we have shown that heterologously expressed rat melanopsin is both N-linked and O-linked glycosylated and that N-linked glycosylation is not crucial for the melanopsin response to light.	Nitrogen	82-83	opsin 4	Rattus norvegicus	63-73
22189909-4	2012	The nutritional parameters measured for the group fed the diet containing CBP showed a positive nitrogen balance of 1.37, a net protein retention of 2.9 and a true digestibility of 95.8%, comparable to those measured for the group fed the casein diet.	Nitrogen	96-104	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	Homo sapiens	74-77
22669605-0	2012	Regulation of anthocyanin biosynthesis by nitrogen in TTG1-GL3/TT8-PAP1-programmed red cells of Arabidopsis thaliana.	Nitrogen	42-50	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	63-66
22415338-5	2012	The effective coordination number of the nitrogen atoms of the ligands around the iron atom has been identified as the order parameter driving the quasi-reversible low-spin to high-spin transition in the crystal.	Nitrogen	41-49	spindlin 1	Homo sapiens	168-172
22415338-5	2012	The effective coordination number of the nitrogen atoms of the ligands around the iron atom has been identified as the order parameter driving the quasi-reversible low-spin to high-spin transition in the crystal.	Nitrogen	41-49	spindlin 1	Homo sapiens	181-185
19236039-7	2009	Furthermore, specific enzyme combinations were necessary to produce suitable peptides for deducing N-glycosylation sites on CXCR4.	Nitrogen	99-100	C-X-C motif chemokine receptor 4	Homo sapiens	124-129
22669605-0	2012	Regulation of anthocyanin biosynthesis by nitrogen in TTG1-GL3/TT8-PAP1-programmed red cells of Arabidopsis thaliana.	Nitrogen	42-50	phosphatidic acid phosphatase 1	Arabidopsis thaliana	67-71
22434609-0	2012	Borylene complexes (BH)L2 and nitrogen cation complexes (N+)L2: isoelectronic homologues of carbones CL2.	Nitrogen	30-38	endogenous retrovirus group W member 5	Homo sapiens	101-104
22669605-2	2012	In this investigation, we report the nitrogen regulation of anthocyanin biosynthesis activated by TTG1-GL3/TT8-PAP1 in red pap1-D cells.	Nitrogen	37-45	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	107-110
22669605-2	2012	In this investigation, we report the nitrogen regulation of anthocyanin biosynthesis activated by TTG1-GL3/TT8-PAP1 in red pap1-D cells.	Nitrogen	37-45	phosphatidic acid phosphatase 1	Arabidopsis thaliana	111-115
19365066-5	2009	Based on existing data and our findings, we propose that cotranslational translocation and N-glycosylation of nascent polypeptides are mediated by a ternary supramolecular complex consisting of OT, the Sec61 complex, and ribosomes.	Nitrogen	91-92	SEC61 translocon subunit alpha 1	Homo sapiens	202-207
22669605-2	2012	In this investigation, we report the nitrogen regulation of anthocyanin biosynthesis activated by TTG1-GL3/TT8-PAP1 in red pap1-D cells.	Nitrogen	37-45	phosphatidic acid phosphatase 1	Arabidopsis thaliana	123-127
22669605-5	2012	An expression analysis of the main regulatory and pathway genes showed that at conditions of higher concentrations of ammonium and total nitrogen, the expression levels of PAP1 and TT8 decreased, but the expression levels of LBD37, 38 and 39, three negative regulators of anthocyanin biosynthesis, increased.	Nitrogen	137-145	phosphatidic acid phosphatase 1	Arabidopsis thaliana	172-176
22427561-0	2012	Glucosamine modulates TNF-alpha-induced ICAM-1 expression and function through O-linked and N-linked glycosylation in human retinal pigment epithelial cells.	Nitrogen	23-24	intercellular adhesion molecule 1	Homo sapiens	40-46
22427561-4	2012	The effect of GlcN on the N-linked glycosylation of ICAM-1 was evaluated by the change in its molecular mass on Western blotting.	Nitrogen	17-18	intercellular adhesion molecule 1	Homo sapiens	52-58
22427561-12	2012	CONCLUSIONS: GlcN inhibits ICAM-1 expression and functions by modulating the O-linked glycosylation of factors involved in NF-kappaB signaling and by reducing the N-linked glycosylation of TNF-alpha-induced ICAM-1 in ARPE-19 cells.	Nitrogen	2-3	intercellular adhesion molecule 1	Homo sapiens	27-33
22446090-3	2012	Here we report that N-methylation of 1a greatly increases its potency and results in excellent selectivity for SIRT2 over SIRT1 and SIRT3 isoforms.	Nitrogen	20-21	sirtuin 1	Homo sapiens	122-127
19301818-7	2009	The effect of media additives phthalate, casamino acids, and yeast nitrogen base on Hpf2 production in P. pastoris were also evaluated.	Nitrogen	67-75	Pst1p	Saccharomyces cerevisiae S288C	84-88
18674860-1	2009	Nitrogen-doped titania nanoparticles consisting of pure anatase, pure rutile and bicrystallites (anatase+rutile and anatase+brookite) have been prepared in TiCl(3)-HMT (hexamethylene tetramine)-alcohol solution under solvothermal process.	Nitrogen	0-8	histamine N-methyltransferase	Homo sapiens	164-167
22669605-5	2012	An expression analysis of the main regulatory and pathway genes showed that at conditions of higher concentrations of ammonium and total nitrogen, the expression levels of PAP1 and TT8 decreased, but the expression levels of LBD37, 38 and 39, three negative regulators of anthocyanin biosynthesis, increased.	Nitrogen	137-145	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	181-184
22669605-7	2012	In contrast, at conditions of lower concentrations of ammonium and total nitrogen, the expression levels of PAP1, TT8 and the main pathway genes increased, whereas those of LBD37, 38 and 39 decreased.	Nitrogen	73-81	phosphatidic acid phosphatase 1	Arabidopsis thaliana	108-112
22669605-7	2012	In contrast, at conditions of lower concentrations of ammonium and total nitrogen, the expression levels of PAP1, TT8 and the main pathway genes increased, whereas those of LBD37, 38 and 39 decreased.	Nitrogen	73-81	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	114-117
19320504-2	2009	Subsequent N-O bond reduction of the hydroxamate has provided access to amide analogues for SAR studies.	Nitrogen	11-12	sarcosine dehydrogenase	Homo sapiens	92-95
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	24-32	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	204-207
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	24-32	phosphatidic acid phosphatase 1	Arabidopsis thaliana	208-212
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	116-124	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	204-207
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	116-124	phosphatidic acid phosphatase 1	Arabidopsis thaliana	208-212
20107545-2	2009	Recently, it has been shown that N-glycosylation affects the binding activity of the Tim-3-Ig fusion protein to its ligand, galectin-9, but the binding properties of non-glycosylated Tim-3 on CD4(+)CD25(+) T cells has not been fully examined.	Nitrogen	33-34	hepatitis A virus cellular receptor 2	Homo sapiens	85-90
22669605-9	2012	Based on these observations, we propose that the regulatory mechanism of nitrogen may occur via two pathways to control the expression of genes encoding positive and negative regulators in red pap1-D cells.	Nitrogen	73-81	phosphatidic acid phosphatase 1	Arabidopsis thaliana	193-197
24900407-1	2012	Tri- and tetracyclic nitrogen-bridgehead compounds were designed and synthesized to yield micromolar cholinesterase (ChE) inhibitors.	Nitrogen	21-29	butyrylcholinesterase	Homo sapiens	101-115
19226165-4	2009	Depending on the NSG substituent, certain of these hybrids exhibited up to 40-fold higher Shc SH2 domain-binding affinity than the parent Gly-containing peptide (IC50 = 248 microM) (for example, for N-homoallyl analogue 50, IC50 = 6 microM).	Nitrogen	17-18	SHC adaptor protein 1	Homo sapiens	90-93
21582568-1	2009	In the structure of the title compound, C(20)H(18)N(4)O(2), the N-H and C=O bonds are trans to each other and the amide O atoms are syn to the ortho amino N atom in the benzoyl rings.	Nitrogen	50-51	synemin	Homo sapiens	132-135
24900407-1	2012	Tri- and tetracyclic nitrogen-bridgehead compounds were designed and synthesized to yield micromolar cholinesterase (ChE) inhibitors.	Nitrogen	21-29	butyrylcholinesterase	Homo sapiens	117-120
22739353-1	2012	Counterintuitive amine lone pair   pi interactions are computationally revealed by MP2 and CCSD(T) methods, attractive lone pair   pi interactions are observed when the lone pair of nitrogen points toward the pi system.	Nitrogen	182-190	tryptase pseudogene 1	Homo sapiens	83-86
19199613-4	2009	In this work, we measure 2D IR spectra of a 3(10)-helical hexapeptide, Z-Aib-l-Leu-(Aib)(2)-Gly-Aib-OtBu, and its (13)C=(18)O-Leu monolabeled and (13)C=(18)O-Leu/(15)N-Gly bis-labeled isotopomers in CDCl(3).	Nitrogen	166-167	ANIB1	Homo sapiens	73-76
19199613-4	2009	In this work, we measure 2D IR spectra of a 3(10)-helical hexapeptide, Z-Aib-l-Leu-(Aib)(2)-Gly-Aib-OtBu, and its (13)C=(18)O-Leu monolabeled and (13)C=(18)O-Leu/(15)N-Gly bis-labeled isotopomers in CDCl(3).	Nitrogen	166-167	ANIB1	Homo sapiens	84-87
19199613-4	2009	In this work, we measure 2D IR spectra of a 3(10)-helical hexapeptide, Z-Aib-l-Leu-(Aib)(2)-Gly-Aib-OtBu, and its (13)C=(18)O-Leu monolabeled and (13)C=(18)O-Leu/(15)N-Gly bis-labeled isotopomers in CDCl(3).	Nitrogen	166-167	ANIB1	Homo sapiens	84-87
22796043-5	2012	Alternatively, a p-halo-benzyl group was introduced at C-2, leaving the indolic nitrogen free.	Nitrogen	80-88	complement C2	Homo sapiens	55-58
19015848-5	2009	The high ammonia had no significant impact on cell growth and oxygen respiratory activity but significantly depressed the activities of glutamine synthetase/glutamate synthase and glutamate dehydrogenase, suggesting that ammonium ion as a nitrogen source improved the protein expression by mediating ammonia-assimilating enzymes.	Nitrogen	239-247	glutamate dehydrogenase	Escherichia coli	157-203
23765721-6	2009	Studies performed in cultures under nitrogen starvation, or with inhibitors of the nitrogen assimilation, suggest that the main role of glutamate dehydrogenase is not the assimilation of ammonium.	Nitrogen	83-91	AKG35_RS03270	Prochlorococcus marinus str. MIT 9313	136-159
23765721-9	2009	We suggest that the main physiological role of glutamate dehydrogenase in Prochlorococcus MIT9313 is the utilization of glutamate to produce ammonium and 2-oxoglutarate, and amino acid recycling, thus enabling to use amino acids as nitrogen source.	Nitrogen	232-240	AKG35_RS03270	Prochlorococcus marinus str. MIT 9313	47-70
18995910-5	2009	All 5 insertions, 2 N-glycosylation sites, most of the cysteines, the conserved aspartate, the TM and each of the cytoplasmic regions are essential for TLR8 signaling.	Nitrogen	20-21	toll-like receptor 8	Bos taurus	152-156
19197361-4	2009	Global transcriptional profiling revealed evolutionarily conserved roles for Tor1 in regulating the expression of genes involved in nitrogen starvation responses and ribosome biogenesis.	Nitrogen	132-140	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	77-81
19062120-6	2009	Furthermore, MEP2 expression was modulated by the ammonium concentration, indicating that nitrogen catabolite repression (NCR) is active during the rehydration phase.	Nitrogen	90-98	ammonium permease MEP2	Saccharomyces cerevisiae S288C	13-17
19146659-9	2009	Furthermore, CRP regulons in different cyanobacterial species/ecotypes are also highly diversified, ranging from photosynthesis, carbon fixation and nitrogen assimilation, to chemotaxis and signal transduction.	Nitrogen	149-157	catabolite gene activator protein	Escherichia coli	13-16
19012434-2	2009	The various N-protected zeta-amino allylic alcohols cyclize in the presence of PdCl2(CH3CN)2 to give substituted piperidines with high stereoselectivities.	Nitrogen	12-13	phosducin like 2	Homo sapiens	79-84
19400163-0	2009	Highly selective cyclic hexapeptides antagonist of GPIIb-IIIa by multiple N-methylation.	Nitrogen	74-75	integrin subunit alpha 2b	Homo sapiens	51-56
19016713-1	2009	Nitrogen-containing bisphosphonates indirectly activate Vgamma9Vdelta2 T cells through inhibition of farnesyl pyrophosphate synthase and intracellular accumulation of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), but the cells responsible for Vgamma9Vdelta2 T cell activation through IPP/DMAPP accumulation are unknown.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	101-132
19508227-1	2009	We showed that Tspan-1, a tetraspanin overexpressed in many human cancers, harbours oligosaccharides at all four potential N-glycosylation sites.	Nitrogen	123-124	tetraspanin 1	Homo sapiens	15-22
19087308-5	2008	RESULTS: We found that the KRAS G12V state deregulated several genes associated to cell cycle, apoptosis and nitrogen metabolism.	Nitrogen	109-117	KRAS proto-oncogene, GTPase	Homo sapiens	27-31
18971945-6	2008	N binds directly to the 43S pre-initiation complex facilitating loading of ribosomes onto capped mRNA functionally replacing eIF4G.	Nitrogen	0-1	eukaryotic translation initiation factor 4 gamma 1	Homo sapiens	125-130
22444092-7	2008	Milk total n-3 polyunsaturated fatty acid (PUFA) content decreased with higher amounts of MS in the diet and n-6 PUFA concentration increased, leading to an elevated n-6 : n-3 PUFA ratio.	Nitrogen	11-12	PUFA	Bos taurus	43-47
19060393-0	2008	Two N-linked glycosylation sites (Asn18 and Asn106) are both required for full enzymatic activity, thermal stability, and resistance to proteolysis in mammalian deoxyribonuclease I.	Nitrogen	4-5	deoxyribonuclease 1	Homo sapiens	161-180
18989571-4	2008	The sequence analysis of LMP-1 predicts two potential N-glycosylation sites and several O-glycosylation sites.	Nitrogen	54-55	PDZ and LIM domain 7	Homo sapiens	25-30
18941214-2	2008	Using CD4(+) T cells from wild-type control and fat-1 transgenic mice (enriched in n-3 PUFA), we show that membrane raft accumulation assessed by Laurdan (6-dodecanoyl-2-dimethyl aminonaphthalene) labeling was enhanced in fat-1 cells following immunological synapse (IS) formation by CD3-specific Ab expressing hybridoma cells.	Nitrogen	3-4	CD4 antigen	Mus musculus	6-9
18941214-2	2008	Using CD4(+) T cells from wild-type control and fat-1 transgenic mice (enriched in n-3 PUFA), we show that membrane raft accumulation assessed by Laurdan (6-dodecanoyl-2-dimethyl aminonaphthalene) labeling was enhanced in fat-1 cells following immunological synapse (IS) formation by CD3-specific Ab expressing hybridoma cells.	Nitrogen	3-4	FAT atypical cadherin 1	Mus musculus	48-53
18846302-3	2008	For protonated pure water clusters, H3O(+)(H2O)n, reacting with D2O the main H/D exchange mechanism is found to be proton catalyzed.	Nitrogen	9-10	H3 clustered histone 15	Homo sapiens	36-39
18783212-5	2008	The reactivity of these chemical systems closely resembles the proposed oxidative N-dealkylation mechanisms that are effected by the copper monooxygenases, dopamine beta-monooxygenase (DbetaM) and peptidylglycine- alpha-hydroxylating monooxygenase (PHM).	Nitrogen	82-83	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	156-247
18783212-5	2008	The reactivity of these chemical systems closely resembles the proposed oxidative N-dealkylation mechanisms that are effected by the copper monooxygenases, dopamine beta-monooxygenase (DbetaM) and peptidylglycine- alpha-hydroxylating monooxygenase (PHM).	Nitrogen	82-83	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	249-252
18782110-2	2008	We have previously demonstrated that n-Nonanoyl-CC chemokine ligand 14 (NNY-CCL14), a modified analog of the naturally occurring chemokine CCL14(9-74) internalizes and desensitizes human CCR3 resulting in the inactivation of eosinophils.	Nitrogen	23-24	C-C motif chemokine receptor 3	Homo sapiens	187-191
18242769-2	2008	In the present work we analyzed expression of the PAL genes in leaves of Arabidopsis thaliana rosette-stage plants in response to nitrogen depletion at temperatures ranging from 5 to 30 degrees C. Only PAL1 and PAL2 responded strongly to both environmental factors, nitrogen and temperature.	Nitrogen	130-138	phenylalanine ammonia-lyase 2	Arabidopsis thaliana	211-215
18242769-2	2008	In the present work we analyzed expression of the PAL genes in leaves of Arabidopsis thaliana rosette-stage plants in response to nitrogen depletion at temperatures ranging from 5 to 30 degrees C. Only PAL1 and PAL2 responded strongly to both environmental factors, nitrogen and temperature.	Nitrogen	266-274	phenylalanine ammonia-lyase 2	Arabidopsis thaliana	211-215
18242769-3	2008	Regardless of nitrogen treatments, PAL1 and 2 transcript levels increased at 5 and 10 degrees C. Averaged across all temperatures, nitrogen depletion led to a two-fold increase in PAL1 and PAL2 transcripts.	Nitrogen	131-139	phenylalanine ammonia-lyase 2	Arabidopsis thaliana	189-193
18674515-0	2008	The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.	Nitrogen	73-75	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	38-44
18596236-2	2008	Here, we show that UNC-18 has a chaperone function in neurons, promoting anterograde transport of the plasma membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein Syntaxin-1.	Nitrogen	20-21	t-SNARE coiled-coil homology domain-containing protein	Caenorhabditis elegans	204-212
18721313-0	2008	Supply of nitrogen can reverse senescence processes and affect expression of genes coding for plastidic glutamine synthetase and lysine-ketoglutarate reductase/saccharopine dehydrogenase.	Nitrogen	10-18	lysine-ketoglutarate reductase/saccharopine dehydrogenase bifunctional enzyme	Arabidopsis thaliana	129-186
21201681-1	2008	In the title compound, C(13)H(13)NO(2)S, the conformation of the N-H bond is anti to the ortho-methyl group on the aniline ring, in contrast to the syn conformation observed with respect to the ortho-chloro group in N-(2-chloro-phen-yl)benzene-sulfonamide.	Nitrogen	33-34	synemin	Homo sapiens	148-151
18639462-0	2008	Nitrogen-containing flavonoid analogues as CDK1/cyclin B inhibitors: synthesis, SAR analysis, and biological activity.	Nitrogen	0-8	sarcosine dehydrogenase	Homo sapiens	80-83
22587283-0	2012	Spin coherence during optical excitation of a single nitrogen-vacancy center in diamond.	Nitrogen	53-61	spindlin 1	Homo sapiens	0-4
22587283-1	2012	We examine the quantum spin state of a single nitrogen-vacancy (NV) center in diamond at room temperature as it makes a transition from the orbital ground state (GS) to the orbital excited state (ES) during nonresonant optical excitation.	Nitrogen	46-54	spindlin 1	Homo sapiens	23-27
22437718-1	2012	The enzyme tyrosinase contains two Cu(I) centres, trigonally coordinated by imidazole nitrogens of six conserved histidine residues.	Nitrogen	86-95	tyrosinase	Homo sapiens	11-21
21890503-8	2012	In general, a functional association was found between the glycosaminoglycan and N-glycosylated chains attached to the central core proteins of syndecan-4 and glypican-1 affecting their regulation of muscle cell proliferation, differentiation, and FGF2 responsiveness.	Nitrogen	81-82	glypican 1	Homo sapiens	159-169
22755133-1	2012	Foam-like carbon (carbon nanofoam, CNF) which belongs to the porous carbon family is formed by pulsed laser ablation of graphite in liquid nitrogen.	Nitrogen	139-147	NPHS1 adhesion molecule, nephrin	Homo sapiens	35-38
22108913-1	2012	The intestinal H(+)/peptide cotransporter 1 (PepT1) plays a major role in nitrogen supply to the body by mediating intestinal absorption of di- and tripeptides.	Nitrogen	74-82	solute carrier family 15 (oligopeptide transporter), member 1	Mus musculus	45-50
22177984-1	2012	Human flavin-containing monooxygenase 3 (hFMO3) is a microsomal drug-metabolizing monooxygenase that catalyzes the NADPH-dependent oxygenation of a wide range of drugs and xenobiotics which contain a soft-nucleophiles, usually sulfur or nitrogen.	Nitrogen	237-245	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	6-39
22177984-1	2012	Human flavin-containing monooxygenase 3 (hFMO3) is a microsomal drug-metabolizing monooxygenase that catalyzes the NADPH-dependent oxygenation of a wide range of drugs and xenobiotics which contain a soft-nucleophiles, usually sulfur or nitrogen.	Nitrogen	237-245	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	41-46
22123080-0	2012	N-Glycosylation pattern of recombinant human CD82 (KAI1), a tumor-associated membrane protein.	Nitrogen	0-1	CD82 molecule	Homo sapiens	45-49
22123080-0	2012	N-Glycosylation pattern of recombinant human CD82 (KAI1), a tumor-associated membrane protein.	Nitrogen	0-1	CD82 molecule	Homo sapiens	51-55
22123080-4	2012	In the current study, a detailed characterization of the recombinant human CD82 N-linked glycosylation pattern was conducted by employing an integrative proteomic and glycomic approach, including glycosidase and protease digestions, glycan permethylation, MS analyses, site-directed mutagenesis, and lectin blots.	Nitrogen	80-81	CD82 molecule	Homo sapiens	75-79
22024534-0	2012	Arabidopsis beta1,2-xylosyltransferase: substrate specificity and participation in the plant-specific N-glycosylation pathway.	Nitrogen	102-103	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	12-19
23155433-7	2012	miR826, a newly identified N-starvation-induced miRNA, was found to target the AOP2 gene.	Nitrogen	27-28	MIR826a	Arabidopsis thaliana	0-6
23155433-9	2012	miR160, miR167, and miR171 could be responsible for the development of Arabidopsis root systems under N-starvation conditions.	Nitrogen	102-103	MIR160a	Arabidopsis thaliana	0-6
22192458-1	2011	BACKGROUND: The Anaplastic Lymphoma Kinase (ALK) is an orphan receptor tyrosine kinase, which undergoes post-translational N-linked glycosylation.	Nitrogen	8-9	ALK receptor tyrosine kinase	Homo sapiens	16-42
22192458-1	2011	BACKGROUND: The Anaplastic Lymphoma Kinase (ALK) is an orphan receptor tyrosine kinase, which undergoes post-translational N-linked glycosylation.	Nitrogen	8-9	ALK receptor tyrosine kinase	Homo sapiens	44-47
22192458-5	2011	We hypothesized that ALK function may depend on N-linked glycosylation and that disruption of this post-translational modification would impair ALK activation, regardless the presence of either gene mutations or overexpression.	Nitrogen	48-49	ALK receptor tyrosine kinase	Homo sapiens	21-24
22192458-13	2011	Furthermore, inhibition of N-linked glycosylation considerably impaired cell viability only of ALK mutated/amplified NB cells.	Nitrogen	27-28	ALK receptor tyrosine kinase	Homo sapiens	95-98
22192458-15	2011	CONCLUSIONS: In this study we showed that inhibition of N-linked glycosylation affects ALK phosphorylation and disrupts downstream pro-survival signaling, indicating that inhibition of this post-translational modification may be a promising therapeutic approach.	Nitrogen	2-3	ALK receptor tyrosine kinase	Homo sapiens	87-90
22192458-17	2011	Future studies will assess whether the efficacy in inhibiting ALK activity might be enhanced by the combination of ALK specific small molecule and N-linked glycosylation inhibitors.	Nitrogen	147-148	ALK receptor tyrosine kinase	Homo sapiens	62-65
19241585-1	2008	Polysaccharides from Auricularia auricula (AAP) extracted in hot water and precipitated by ethanol were chemically well defined, including 42.5% total carbohydrate, 19.6% uronic acids, 15.8% sulfate groups, 1.7% N, and 20.3% ash.	Nitrogen	212-213	active avoidance performance	Mus musculus	43-46
18593165-4	2008	In this work, we have used (15)N-HSQC based NMR titration experiments of a 12-residue peptide substrate with AcpS to identify six specifically interacting residues (S3, L4, D5, M6, W9, and L11) without the formation of any notable secondary structure.	Nitrogen	31-32	immunoglobulin kappa variable 1-6	Homo sapiens	189-192
22846176-5	2012	During nitrogen-limited sluggish fermentation, glucose uptake capacity was reduced to approximately 20% of its initial values (Vmax = 4.9 +- 0.8 compared to 21.9 +- 1.2 mumol h-1 10-8 cells), being presumably sustained by the low-affinity glucose transporter Hxt3p (considering the calculated Km = 39.2 +- 8.6 mM).	Nitrogen	7-15	hexose transporter HXT3	Saccharomyces cerevisiae S288C	259-264
18588887-0	2008	N-Glycosylation of the Drosophila neural protein Chaoptin is essential for its stability, cell surface transport and adhesive activity.	Nitrogen	0-1	chaoptin	Drosophila melanogaster	49-57
18588887-4	2008	Here we show that mutations introduced into about 1/3 of 16 potential N-linked glycosylation sites within Chp impaired its cell adhesive activities when expressed in Drosophila S2 cells.	Nitrogen	70-71	chaoptin	Drosophila melanogaster	106-109
18588887-6	2008	These results suggest that N-linked glycosylation of Chp is essential for its stability and activity.	Nitrogen	27-28	chaoptin	Drosophila melanogaster	53-56
21900457-7	2011	Expressing FXYD5 in M1 cells resulted in a decrease in N-glycosylation of beta1 Na(+)-K(+)-ATPase, while silencing it in H1299 cells had an opposite effect.	Nitrogen	55-56	FXYD domain containing ion transport regulator 5	Homo sapiens	11-16
22607976-0	2012	STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.	Nitrogen	34-35	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	0-5
21978679-4	2011	We report here the second part of the strategy used in our research group to find a new class of HDAC inhibitors, namely the SAR study for the compounds bearing a sulfonyl group on the piperidine nitrogen.	Nitrogen	196-204	histone deacetylase 9	Homo sapiens	97-101
22496396-5	2012	CYP2C9 and CYP2C19 were the primary enzymes responsible for formation of the N-hydroxylated metabolite.	Nitrogen	77-78	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	0-6
22219998-1	2011	In the title compound, C(12)H(7)Cl(4)NO(2)S, the N-H bond in the C-SO(2)-NH-C segment is syn with respect to the ortho-Cl atom of the sulfonyl-benzene ring and one of the meta-Cl atoms of the aniline ring.	Nitrogen	37-38	synemin	Homo sapiens	89-92
21932778-3	2011	Here, we studied the role of the possible N-glycosylation sites at Asn-79 and Asn-116 in recombinant anchorless glypican-1 expressed in eukaryotic cells.	Nitrogen	42-43	glypican 1	Homo sapiens	112-122
21932778-5	2011	Experiments using the drug tunicamycin to inhibit the N-linked glycosylation of glypican-1 showed that secretion of anchorless glypican-1 was reduced and that the protein did not accumulate inside the cells.	Nitrogen	54-55	glypican 1	Homo sapiens	80-90
18632577-4	2008	The crystal structure suggests that most of the UL18 surface, except where LIR-1 and the host-derived light chain bind, is covered by carbohydrates attached to 13 potential N-glycosylation sites, thereby preventing access to bound peptide and association with most MHCI-binding proteins.	Nitrogen	173-174	membrane glycoprotein UL18	Human betaherpesvirus 5	48-52
18591743-7	2008	(vi) alpha-Kl in urine increases TRPV5 channel abundance at the luminal cell surface by hydrolyzing the N-linked extracellular sugar residues of TRPV5, resulting in increased Ca(2+) influx from the lumen.	Nitrogen	104-105	klotho	Mus musculus	5-13
18358511-10	2008	These results suggest that male SD rats are more sensitive to MDMA acute toxicity than are females, probably because their CYP1A2 is more active, leading to higher N-demethylation and plasma MDA concentration.	Nitrogen	164-165	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	123-129
18595314-11	2008	Ammonium activation of the PKA pathway in nitrogen-starved cells is mediated mainly by the Mep2 transceptor, which belongs to a different class of transporter proteins.	Nitrogen	42-50	ammonium permease MEP2	Saccharomyces cerevisiae S288C	91-95
21945320-0	2011	Biochemical engineering of the N-acyl side chain of sialic acids alters the kinetics of a glycosylated potassium channel Kv3.1.	Nitrogen	31-32	potassium voltage-gated channel subfamily C member 1	Homo sapiens	121-126
18340083-3	2008	Here, we show that mouse GPIHBP1 is N-glycosylated at Asn-76 within the Ly-6 domain.	Nitrogen	36-37	lymphocyte antigen 6 complex	Mus musculus	72-76
24475394-4	2012	Recently Rafieian-Kopaei and colleagues showed that erythropoietin significantly ameliorated serum creatinine, blood urea nitrogen and tubal necrosis in gentamicin induced nephrotoxicity in rat.	Nitrogen	122-130	erythropoietin	Rattus norvegicus	52-66
18214569-7	2008	The antiresorptive effects of the nitrogen-containing BPs (including alendronate, risedronate, ibandronate, and zoledronate) appear to result from their inhibition of the enzyme farnesyl pyrophosphate synthase (FPPS) in osteoclasts.	Nitrogen	34-42	farnesyl diphosphate synthase	Homo sapiens	178-209
18214569-7	2008	The antiresorptive effects of the nitrogen-containing BPs (including alendronate, risedronate, ibandronate, and zoledronate) appear to result from their inhibition of the enzyme farnesyl pyrophosphate synthase (FPPS) in osteoclasts.	Nitrogen	34-42	farnesyl diphosphate synthase	Homo sapiens	211-215
22058755-1	2011	The title mol-ecule, C(13)H(17)ClN(2)O(3)S, shows an anti and syn disposition of the butanoyl and 2,5-dimethoxyphenyl groups with respect to the thione and is stabilized by intra-molecular N-H O and weak C-H S hydrogen bonds.	Nitrogen	33-34	synemin	Homo sapiens	62-65
24031762-2	2011	The results showed that using soybean meal as a nitrogen source, alpha-amylase secreted from C. versicolor expressed 407.25U/g of activity, leading to 45.15% of starch degraded.	Nitrogen	48-56	1,4-alpha-glucan-branching enzyme 1, chloroplastic/amyloplastic	Glycine max	65-78
24475394-6	2012	They showed that erythropoietin improved significantly serum creatinine and blood urea nitrogen in gentamicin injected rats simultaneously and even after gentamicin nephrotoxicity induction.	Nitrogen	87-95	erythropoietin	Rattus norvegicus	17-31
21894462-7	2011	Complementation analysis demonstrated that both UGT splice variants are necessary for N- and O-glycosylation of proteins.	Nitrogen	86-87	solute carrier family 35 member A2	Canis lupus familiaris	48-51
22561161-1	2012	Doppel (Dpl) protein is a paralog of the prion protein (PrP) that shares 25% sequence similarity with the C-terminus of PrP, a common N-glycosylation site and a C-terminal signal peptide for attachment of a glycosylphophatidyl inositol anchor.	Nitrogen	134-135	prion like protein doppel	Mus musculus	0-6
21740978-11	2011	(2) The distance between the SXXK-motif Lys-NZ atom and the Lys/His-nitrogen atom of the (K/H)T(S)G-motif was highly conserved, suggesting importance for PBP function, and a possibly conserved role in the catalytic mechanism of the PBPs.	Nitrogen	68-76	phosphatidylethanolamine binding protein 1	Homo sapiens	154-157
18445491-6	2008	Western blot assay revealed that CBA/N mice showed constant expression of Hsp70 and Hsp110 with age, but not in DBA/2J mice.	Nitrogen	37-38	heat shock 105kDa/110kDa protein 1	Mus musculus	84-90
22561161-1	2012	Doppel (Dpl) protein is a paralog of the prion protein (PrP) that shares 25% sequence similarity with the C-terminus of PrP, a common N-glycosylation site and a C-terminal signal peptide for attachment of a glycosylphophatidyl inositol anchor.	Nitrogen	134-135	prion like protein doppel	Mus musculus	8-11
18004837-6	2008	Twenty-eight individual amide sites in the GB1(A34F) dimer protein were monitored via a 2D (15)N-(1)H HSQC spectroscopy, and all relaxation-derived data are consistent with predominantly an exchange process between dimer and monomer species.	Nitrogen	94-96	gamma-aminobutyric acid type B receptor subunit 1	Homo sapiens	43-46
26593832-7	2012	We compared the binding affinity to N2 with various carbenes (:CF2, :CCl2, :CBr2, and :CI2).	Nitrogen	36-38	C-C motif chemokine ligand 2	Homo sapiens	69-73
18397324-7	2008	These results indicate that PCaP1 tightly binds to the plasma membrane via N-myristoylation at Gly2.	Nitrogen	75-76	plasma-membrane associated cation-binding protein 1	Arabidopsis thaliana	28-33
21823579-9	2011	Furthermore, DUT-30(Zn) exhibits a hydrogen storage capacity of 1.12 wt % at 1 bar, a CO(2) uptake of 200 cm(3) g(-1) at -78  C and 0.9 bar, and a n-butane uptake of 3.0 mmol g(-1) at 20  C. The N(2) adsorption process was monitored in situ via X-ray powder diffraction using synchrotron radiation.	Nitrogen	195-199	deoxyuridine triphosphatase	Homo sapiens	13-16
22058949-1	2011	The title compound, C(7)H(13)NO(5), was prepared by the condensation of O-(carb-oxy-meth-yl)hydroxyl-amine and (Boc)(2)O (Boc = but-oxy-carbon-yl).In the crystal, mol-ecules are linked by weak inter-molecular N-H O hydrogen bonds.	Nitrogen	29-30	BOC cell adhesion associated, oncogene regulated	Homo sapiens	112-115
22058949-1	2011	The title compound, C(7)H(13)NO(5), was prepared by the condensation of O-(carb-oxy-meth-yl)hydroxyl-amine and (Boc)(2)O (Boc = but-oxy-carbon-yl).In the crystal, mol-ecules are linked by weak inter-molecular N-H O hydrogen bonds.	Nitrogen	29-30	BOC cell adhesion associated, oncogene regulated	Homo sapiens	122-125
22732219-6	2012	These results indicate that low nitrate reductase activity due to the AtSIZ1 mutation is correlated with an overall decrease in alternative respiration and with a low carbohydrate content to maintain the carbon to nitrogen ratio in siz1-2 mutants.	Nitrogen	214-222	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	70-76
21775536-6	2011	Extensive amino acid substitutions in the GP5 sequence translated from ORF5 were found, particularly in the potential neutralization epitope and the N-glycosylation sites.	Nitrogen	149-150	CWC15 spliceosome associated protein homolog	Homo sapiens	71-75
18375764-3	2008	CyaA utilizes a heavily N-glycosylated beta(2) integrin receptor CD11b/CD18 (alpha(M)beta(2), Mac-1, or CR3).	Nitrogen	24-25	integrin subunit alpha M	Homo sapiens	65-70
18375764-3	2008	CyaA utilizes a heavily N-glycosylated beta(2) integrin receptor CD11b/CD18 (alpha(M)beta(2), Mac-1, or CR3).	Nitrogen	24-25	integrin subunit alpha M	Homo sapiens	94-99
18375764-4	2008	We show that deglycosylation of cell surface proteins by glycosidase treatment, or inhibition of protein N-glycosylation by tunicamycin, ablates CyaA binding and penetration of CD11b-expressing cells.	Nitrogen	105-106	integrin subunit alpha M	Homo sapiens	177-182
22387313-0	2012	N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.	Nitrogen	0-1	dipeptidyl peptidase like 10	Homo sapiens	33-74
18391423-3	2008	Crystals suitable for X-ray diffraction analysis were only obtained with mutants of IL-22 and sIL-22R1 that removed the N-linked glycosylation sites found in the wild-type amino-acid sequences.	Nitrogen	120-121	interleukin 22	Homo sapiens	84-89
18216145-16	2008	Administration of recombinant netrin-1 significantly improved kidney function (blood urea nitrogen: 161 +/- 7 vs. 104 +/- 24 mg/dl, creatinine: 1.3 +/- 0.07 vs. 0.75 +/- 0.16 mg/dl, P &lt; 0.05 at 24 h) and reduced tubular damage and leukocyte infiltration in the outer medulla.	Nitrogen	90-98	netrin 1	Homo sapiens	30-38
18454049-4	2008	Recently, we reported that nitrogen-containing bisphosphonates (N-BPs) induce formation of a novel ATP analog (ApppI) as a consequence of the inhibition of farnesyl diphosphate synthase in the mevalonate pathway.	Nitrogen	27-35	farnesyl diphosphate synthase	Homo sapiens	156-185
21680215-6	2011	The hydrogen-bond acceptor was the pyridine nitrogen of NNK in the CYP2A13 complex, but it changed to the carbonyl oxygen in the CYP2A6 complex.	Nitrogen	44-52	cytochrome P450 family 2 subfamily A member 13	Homo sapiens	67-74
21680215-6	2011	The hydrogen-bond acceptor was the pyridine nitrogen of NNK in the CYP2A13 complex, but it changed to the carbonyl oxygen in the CYP2A6 complex.	Nitrogen	44-52	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	129-135
21712391-0	2011	Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95.	Nitrogen	85-86	inactive glutathione hydrolase 2	Homo sapiens	32-61
21712391-3	2011	GGT is extensively N-glycosylated, yet the functional consequences of this modification are unclear.	Nitrogen	19-20	inactive glutathione hydrolase 2	Homo sapiens	0-3
21712391-4	2011	We investigated the effect of N-glycosylation on the kinetic behavior, stability, and functional maturation of GGT.	Nitrogen	30-31	inactive glutathione hydrolase 2	Homo sapiens	111-114
21712391-5	2011	Using site-directed mutagenesis, we confirmed that all seven N-glycosylation sites on human GGT are modified by N-glycans.	Nitrogen	61-62	inactive glutathione hydrolase 2	Homo sapiens	92-95
21712391-9	2011	Use of N-glycosylation inhibitors demonstrated that binding of the core N-glycans, not their subsequent processing, is the critical glycosylation event governing the autocleavage of GGT.	Nitrogen	7-8	inactive glutathione hydrolase 2	Homo sapiens	182-185
21712391-11	2011	These findings are the first to establish that co-translational N-glycosylation of human GGT is required for the proper folding and subsequent cleavage of the nascent propeptide, although retention of these N-glycans is not necessary for maintaining either the function or structural stability of the mature enzyme.	Nitrogen	64-65	inactive glutathione hydrolase 2	Homo sapiens	89-92
18180269-7	2008	N-Dealkylation of 1, the principal metabolic route observed in vivo, was found to be predominately monoamine oxidase-B-mediated with the resulting putative aldehyde intermediate undergoing subsequent oxidation to 2 or reduction to 3.	Nitrogen	0-1	monoamine oxidase B	Homo sapiens	99-118
22387313-0	2012	N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.	Nitrogen	0-1	dipeptidyl peptidase like 10	Homo sapiens	76-81
22387313-3	2012	DPP10 is a glycoprotein containing eight predicted N-glycosylation sites in the extracellular domain.	Nitrogen	51-52	dipeptidyl peptidase like 10	Homo sapiens	0-5
22387313-4	2012	In this study we investigated the role of N-glycosylation on DPP10 trafficking and functional activity.	Nitrogen	42-43	dipeptidyl peptidase like 10	Homo sapiens	61-66
23028207-0	2012	An N-glycosylation Analysis of Human Alpha-2-Macroglobulin Using an Integrated Approach.	Nitrogen	3-4	alpha-2-macroglobulin	Homo sapiens	37-58
18275518-0	2008	N-glycosylation is required for binding of murine pregnancy-specific glycoproteins 17 and 19 to the receptor CD9.	Nitrogen	0-1	CD9 antigen	Mus musculus	109-112
23028207-2	2012	Herein, the detailed N-glycosylation pattern of human serum alpha-2-macroglobulin was studied using an integrative approach, including permethylation of N-glycans, collision induced dissociation (CID) and electron transfer dissociation (ETD) of chymotryptic N-glycopeptides, and partial deglycosylation of chymotryptic N-glycopeptides with endo-beta-N-acetylglucosaminidase F3 (Endo F3).	Nitrogen	21-22	alpha-2-macroglobulin	Homo sapiens	60-81
18211077-2	2008	The corresponding syn diastereoisomers are obtained when the starting imines are reduced and the nitrogen atom is conveniently protected.	Nitrogen	97-105	synemin	Homo sapiens	18-21
22331994-3	2012	Here, we report the effects of BSA on CYP1A2-catalyzed phenacetin (PHEN) O-deethylation and lidocaine (LID) N-deethylation using HLM and Escherichia coli-expressed recombinant human CYP1A2 (rCYP1A2) as the enzyme sources.	Nitrogen	70-71	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	38-44
18198892-8	2008	The unstable HN5/N5- produced at -40 degrees C did not build up in the solution but degraded to azide ion and nitrogen gas with a short lifetime.	Nitrogen	110-118	MT-RNR2 like 5 (pseudogene)	Homo sapiens	13-16
22351292-5	2012	The metastable process that creates the most prevalent peak is shown to be C(5)H(5)N(+)   C(4)H(4)(+) + HCN.	Nitrogen	83-84	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	104-107
17980859-6	2008	Kinetic and inhibition studies indicated that the side-chain N-dealkylation is mediated by CYP2C11 and CYP3A2, whereas the aromatic ring O-demethylation is mediated by CYP2D2 and CYP2C6 in untreated male rats.	Nitrogen	61-62	cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1	Rattus norvegicus	179-185
18337696-0	2008	Nitrogen depletion causes up-regulation of glutathione content and gamma-glutamyltranspeptidase in Schizosaccharomyces pombe.	Nitrogen	0-8	inactive glutathione hydrolase 2	Homo sapiens	67-95
22286559-2	2012	Some of the N-substituted epsilon-hexonolactams show better enhancements to N370S mutant beta-glucocerebrosidase activity than NB-DNJ and NN-DNJ.	Nitrogen	12-13	glucosylceramidase beta	Homo sapiens	89-112
18337696-5	2008	Activity of gamma-glutamyltranspeptidase (gamma-GT), an enzyme in the first step of GSH catabolism, also increased during nitrogen depletion.	Nitrogen	122-130	inactive glutathione hydrolase 2	Homo sapiens	12-40
18337696-5	2008	Activity of gamma-glutamyltranspeptidase (gamma-GT), an enzyme in the first step of GSH catabolism, also increased during nitrogen depletion.	Nitrogen	122-130	inactive glutathione hydrolase 2	Homo sapiens	42-50
18337696-8	2008	Collectively, nitrogen depletion causes up-regulation of GSH synthesis and gamma-GT in a Pap1-dependent manner.	Nitrogen	14-22	inactive glutathione hydrolase 2	Homo sapiens	75-83
22303015-2	2012	We evaluated the possibility that this mutation, which is located adjacent to the most N-terminal of three beta3 subunit N-glycosylation sites, might reduce GABAergic inhibition by increasing glycosylation of beta3 subunits.	Nitrogen	87-88	basic helix-loop-helix family member e22	Homo sapiens	107-112
18092770-3	2008	Syn orientation for the base and South (S) conformers for the sugar dominate at 298.15 K: syn/anti=62.3%:37.7% and S/N=77.2%:22.8%.	Nitrogen	117-118	synemin	Homo sapiens	0-3
18159923-3	2008	The structure of a factor Xa cocrystal containing 7-fluoroindazole 51a showed the 7-fluoro atom hydrogen-bonding with the N-H of Gly216 (2.9 A) in the peptide backbone.	Nitrogen	122-123	coagulation factor X	Homo sapiens	19-28
22303015-2	2012	We evaluated the possibility that this mutation, which is located adjacent to the most N-terminal of three beta3 subunit N-glycosylation sites, might reduce GABAergic inhibition by increasing glycosylation of beta3 subunits.	Nitrogen	87-88	basic helix-loop-helix family member e22	Homo sapiens	209-214
17963777-4	2008	Moreover, methemoglobin and GDA/n-C5H11OH/H2O assemblies can affect their structures and properties and the change in behavior is dependent on the content of methemoglobin and the composition and structure of the GDA/n-C5H11OH/H2O system.	Nitrogen	22-23	hemoglobin subunit gamma 2	Homo sapiens	158-171
17963777-4	2008	Moreover, methemoglobin and GDA/n-C5H11OH/H2O assemblies can affect their structures and properties and the change in behavior is dependent on the content of methemoglobin and the composition and structure of the GDA/n-C5H11OH/H2O system.	Nitrogen	22-23	guanine deaminase	Homo sapiens	213-216
17963777-4	2008	Moreover, methemoglobin and GDA/n-C5H11OH/H2O assemblies can affect their structures and properties and the change in behavior is dependent on the content of methemoglobin and the composition and structure of the GDA/n-C5H11OH/H2O system.	Nitrogen	25-26	hemoglobin subunit gamma 2	Homo sapiens	10-23
17963777-4	2008	Moreover, methemoglobin and GDA/n-C5H11OH/H2O assemblies can affect their structures and properties and the change in behavior is dependent on the content of methemoglobin and the composition and structure of the GDA/n-C5H11OH/H2O system.	Nitrogen	25-26	guanine deaminase	Homo sapiens	28-31
17963777-4	2008	Moreover, methemoglobin and GDA/n-C5H11OH/H2O assemblies can affect their structures and properties and the change in behavior is dependent on the content of methemoglobin and the composition and structure of the GDA/n-C5H11OH/H2O system.	Nitrogen	25-26	hemoglobin subunit gamma 2	Homo sapiens	158-171
17963777-4	2008	Moreover, methemoglobin and GDA/n-C5H11OH/H2O assemblies can affect their structures and properties and the change in behavior is dependent on the content of methemoglobin and the composition and structure of the GDA/n-C5H11OH/H2O system.	Nitrogen	25-26	guanine deaminase	Homo sapiens	213-216
17963777-5	2008	The relationship among the changes in the structure and properties of GDA/n-C5H11OH/H2O assemblies, the content of methemoglobin, and the composition and structure of GDA/n-C5H11OH/H2O assemblies may provide some important theoretical information for elucidation of the interaction between methemoglobin and blood cell membrane and may also be helpful for the cure of some blood diseases.	Nitrogen	11-12	guanine deaminase	Homo sapiens	70-73
22303015-5	2012	Second, beta3(G32R) subunits were more likely than beta3 subunits to be N-glycosylated at Asn-33, but increases in glycosylation were not responsible for changes in subunit surface expression.	Nitrogen	72-73	basic helix-loop-helix family member e22	Homo sapiens	8-13
17963777-5	2008	The relationship among the changes in the structure and properties of GDA/n-C5H11OH/H2O assemblies, the content of methemoglobin, and the composition and structure of GDA/n-C5H11OH/H2O assemblies may provide some important theoretical information for elucidation of the interaction between methemoglobin and blood cell membrane and may also be helpful for the cure of some blood diseases.	Nitrogen	11-12	hemoglobin subunit gamma 2	Homo sapiens	115-128
17963777-5	2008	The relationship among the changes in the structure and properties of GDA/n-C5H11OH/H2O assemblies, the content of methemoglobin, and the composition and structure of GDA/n-C5H11OH/H2O assemblies may provide some important theoretical information for elucidation of the interaction between methemoglobin and blood cell membrane and may also be helpful for the cure of some blood diseases.	Nitrogen	11-12	guanine deaminase	Homo sapiens	167-170
17963777-5	2008	The relationship among the changes in the structure and properties of GDA/n-C5H11OH/H2O assemblies, the content of methemoglobin, and the composition and structure of GDA/n-C5H11OH/H2O assemblies may provide some important theoretical information for elucidation of the interaction between methemoglobin and blood cell membrane and may also be helpful for the cure of some blood diseases.	Nitrogen	11-12	hemoglobin subunit gamma 2	Homo sapiens	290-303
22303015-5	2012	Second, beta3(G32R) subunits were more likely than beta3 subunits to be N-glycosylated at Asn-33, but increases in glycosylation were not responsible for changes in subunit surface expression.	Nitrogen	72-73	basic helix-loop-helix family member e22	Homo sapiens	51-56
22020754-9	2012	Both the degradation of the cytochrome b6 f complex which occurs in C. reinhardtii upon nitrogen starvation and lower ferredoxin amounts might create a bottleneck impeding the conversion of carbohydrate reserves into hydrogen evolution.	Nitrogen	88-96	cytochrome b	Chlamydomonas reinhardtii	28-40
19137904-2	2008	Six new tri- and tetracyclic nitrogen bridgehead compounds known to be moderate to potent inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in vitro were tested in vivo as experimental therapeutics for treatment of Alzheimer"s disease.	Nitrogen	29-37	butyrylcholinesterase	Rattus norvegicus	136-157
19137904-2	2008	Six new tri- and tetracyclic nitrogen bridgehead compounds known to be moderate to potent inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) in vitro were tested in vivo as experimental therapeutics for treatment of Alzheimer"s disease.	Nitrogen	29-37	butyrylcholinesterase	Rattus norvegicus	159-163
18334732-6	2008	However, the binding patterns of both N- and O-linked glycan-reactive lectins indicated distinct differences in carbohydrate composition between CA125 antigen isolated from amniotic fluid and OVCAR-3 cell line.	Nitrogen	38-39	mucin 16, cell surface associated	Homo sapiens	145-150
22246635-0	2012	The effects of hypoxia on sediment nitrogen cycling in the Baltic Sea.	Nitrogen	35-43	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	66-69
19776625-3	2008	The newly generated fat-1 transgenic mouse was genetically engineered to carry a gene, namely fat-1, from the round worm Caenorhabditis elegans and is capable of converting n-6 to n-3 fatty acids (which is naturally impossible in mammals), leading to an increase in n-3 fatty acid content with a balanced n-6/n-3 fatty acid ratio in all tissues, independent of diet.	Nitrogen	4-5	FAT atypical cadherin 1	Mus musculus	20-25
19776625-3	2008	The newly generated fat-1 transgenic mouse was genetically engineered to carry a gene, namely fat-1, from the round worm Caenorhabditis elegans and is capable of converting n-6 to n-3 fatty acids (which is naturally impossible in mammals), leading to an increase in n-3 fatty acid content with a balanced n-6/n-3 fatty acid ratio in all tissues, independent of diet.	Nitrogen	4-5	FAT atypical cadherin 1	Mus musculus	94-99
19776625-3	2008	The newly generated fat-1 transgenic mouse was genetically engineered to carry a gene, namely fat-1, from the round worm Caenorhabditis elegans and is capable of converting n-6 to n-3 fatty acids (which is naturally impossible in mammals), leading to an increase in n-3 fatty acid content with a balanced n-6/n-3 fatty acid ratio in all tissues, independent of diet.	Nitrogen	12-13	FAT atypical cadherin 1	Mus musculus	20-25
19776625-3	2008	The newly generated fat-1 transgenic mouse was genetically engineered to carry a gene, namely fat-1, from the round worm Caenorhabditis elegans and is capable of converting n-6 to n-3 fatty acids (which is naturally impossible in mammals), leading to an increase in n-3 fatty acid content with a balanced n-6/n-3 fatty acid ratio in all tissues, independent of diet.	Nitrogen	12-13	FAT atypical cadherin 1	Mus musculus	94-99
22126194-3	2012	METHODS: Erythropoietin was injected in the peritoneal space of ICR mice after ischemia/reperfusion injury and its effect was assessed by measuring blood urea nitrogen and creatinine, and by histological analysis.	Nitrogen	159-167	erythropoietin	Mus musculus	9-23
18240547-8	2007	High dietary n-6 PUFA intake may be an important environmental modifier that contributes to inflammatory bowel diseases.	Nitrogen	13-14	pumilio RNA binding family member 3	Homo sapiens	17-21
17707780-9	2007	Moreover, the quantum chemical calculations indicated that the intermolecular hydrogen-bonding interactions play an essential role in determining the relative orientation of CS and EFG tensors of O-6 and nitrogen atoms in the molecular frame axes.	Nitrogen	204-212	immunoglobulin kappa variable 1D-35 (pseudogene)	Homo sapiens	196-199
22126194-6	2012	RESULTS: Erythropoietin administration significantly inhibited the increase in blood urea nitrogen and creatinine after ischemia/reperfusion injury compared with control mice.	Nitrogen	90-98	erythropoietin	Mus musculus	9-23
18184081-8	2007	Although Env sequences from LTNPs differed from those of control patients with respect to the length of variable domains and the number of N-glycosylation sites, these differences were not statistically significant and did not lead to differences in infectivity of recombinant reporter viruses.	Nitrogen	30-31	endogenous retrovirus group K member 20	Homo sapiens	9-12
22024963-8	2012	The T/N ratio showed a statistical correlation with cell density depending             on the degree of necrosis and LAT1 immunopositivity (P=0.002 and 0.032).	Nitrogen	6-7	solute carrier family 7 member 5	Homo sapiens	117-121
18056045-5	2007	The inhibitory effects of the nitrogen-containing BPs (including alendronate, risedronate, ibandronate, and zoledronate) on osteoclasts appear to result from their inhibition of farnesyl pyrophosphate synthase (FPPS), a key branch-point enzyme in the mevalonate pathway.	Nitrogen	30-38	farnesyl diphosphate synthase	Homo sapiens	178-209
22359337-11	2012	Following CYP enzyme kinetic studies, CYP2B6 was the most relevant enzyme for both the N-demethylation of 3-BMC and 3-FMC after in vitro-in vivo extrapolation.	Nitrogen	87-88	cytochrome P450, family 2, subfamily b, polypeptide 3	Rattus norvegicus	38-44
18056045-5	2007	The inhibitory effects of the nitrogen-containing BPs (including alendronate, risedronate, ibandronate, and zoledronate) on osteoclasts appear to result from their inhibition of farnesyl pyrophosphate synthase (FPPS), a key branch-point enzyme in the mevalonate pathway.	Nitrogen	30-38	farnesyl diphosphate synthase	Homo sapiens	211-215
17869101-0	2007	High dopamine transporter selectivity can be displayed by remarkably simple non-nitrogen containing inhibitors.	Nitrogen	80-88	solute carrier family 6 member 3	Homo sapiens	5-25
22101279-1	2012	The NatB complex, Nat5/Mdm20 acetyltransferase mediates N-acetylation to control cell cycle progression and actin dynamics in yeast.	Nitrogen	4-5	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	Mus musculus	23-28
18173125-0	2007	[Effect of nitrogen-containing derivatives of the plant triterpenes betulin and glycyrrhetic acid on the growth of MT-4, MOLT-4, CEM, and Hep G2 tumor cells].	Nitrogen	11-19	metallothionein 4	Homo sapiens	115-119
21786798-0	2011	Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concerted.	Nitrogen	0-8	monoamine oxidase B	Homo sapiens	41-60
21786798-0	2011	Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concerted.	Nitrogen	124-132	monoamine oxidase B	Homo sapiens	41-60
21786798-1	2011	Nitrogen kinetic isotope effects for the oxidation of benzylamine and (1,1-(2)H(2))benzylamine by recombinant human monoamine oxidase B show that cleavage of the CH bond is not concerted with rehybridization of the nitrogen atom.	Nitrogen	0-8	monoamine oxidase B	Homo sapiens	116-135
21786798-1	2011	Nitrogen kinetic isotope effects for the oxidation of benzylamine and (1,1-(2)H(2))benzylamine by recombinant human monoamine oxidase B show that cleavage of the CH bond is not concerted with rehybridization of the nitrogen atom.	Nitrogen	215-223	monoamine oxidase B	Homo sapiens	116-135
21652715-0	2011	Npr1 Ser/Thr protein kinase links nitrogen source quality and carbon availability with the yeast nitrate transporter (Ynt1) levels.	Nitrogen	34-42	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	0-4
21652715-8	2011	Furthermore, Npr1 is phosphorylated in response to the preferred nitrogen sources, and indeed it is dephosphorylated in nitrogen-free medium.	Nitrogen	65-73	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	13-17
17959891-1	2007	Nitrogen-containing bisphosphonates (nBPs) are bone-specific agents that inhibit farnesyl diphosphate synthase.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	81-110
22106404-3	2012	After 4 weeks of Nx, wild-type mice with renal mass reduction exhibited increased blood urea nitrogen, plasma creatinine and phosphorus concentrations, and defective urine concentrating capability, all of which were significantly attenuated by mPGES-1 deletion.	Nitrogen	93-101	prostaglandin E synthase	Mus musculus	244-251
17720268-7	2007	In vitro experiments showed that LDLR activity is increased when cell growth is enhanced by the addition of N2 supplement.	Nitrogen	108-110	low density lipoprotein receptor	Mus musculus	33-37
21652715-8	2011	Furthermore, Npr1 is phosphorylated in response to the preferred nitrogen sources, and indeed it is dephosphorylated in nitrogen-free medium.	Nitrogen	120-128	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	13-17
21652715-12	2011	We concluded that Npr1 plays a key role in adapting Ynt1 levels to the nitrogen quality and availability of a source of carbon.	Nitrogen	71-79	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	18-22
21621882-5	2011	The SAR analysis indicates that the location of nitrogen substituents on the quinone nucleus, the presence of methyl, phenyl, furyl and thienyl groups at the 6-position and the aromatization of the angular cycloaliphatic ring of the phenylamino-3,4-tetrahydrophenanthridine-1,7,10(2H)-trione pharmacophore play key roles in the antitumor activity.	Nitrogen	48-56	sarcosine dehydrogenase	Homo sapiens	4-7
20858066-6	2012	Two novel compounds we report (MP1 and MP2) covalently link ibuprofen and ketoprofen directly to the amide nitrogen of n-acetyl-glucosamine (NAG); the other compound (MP3) covalently links ibuprofen to the amide nitrogen, using a short chain acetyl linker.	Nitrogen	107-115	tryptase pseudogene 1	Homo sapiens	39-42
17599380-3	2007	Here, we identify an HIV Env variant in the V4 region of gp120, Asp 386 (D386), that eliminates an N-linked glycosylation site at position 386, enhances viral replication in macrophages, and is present at a higher frequency in AIDS patients with HIV-associated dementia (HAD) compared with non-HAD patients.	Nitrogen	99-100	endogenous retrovirus group K member 20	Homo sapiens	25-28
21765407-1	2011	We obtained unanticipated synthetic byproducts from alkylation of the delta(1) nitrogen (N3) of the histidine imidazole ring of the polo-like kinase-1 (Plk1) polo-box domain (PBD)-binding peptide PLHSpT.	Nitrogen	79-87	polo like kinase 1	Homo sapiens	132-150
22952687-3	2012	The expressions of most nitrogen metabolism related proteins (e.g. Gdh1p, Met1p) were higher in the parental yeast, indicating that the tolerant yeast decreases its nitrogen metabolism rate to reserve energy, and possesses high resistance to the stress of combined inhibitors.	Nitrogen	24-32	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	67-72
21765407-1	2011	We obtained unanticipated synthetic byproducts from alkylation of the delta(1) nitrogen (N3) of the histidine imidazole ring of the polo-like kinase-1 (Plk1) polo-box domain (PBD)-binding peptide PLHSpT.	Nitrogen	79-87	polo like kinase 1	Homo sapiens	152-156
21606496-4	2011	Using a recombinant fusion protein of the extracellular domain of 2B4, we demonstrate that N-linked glycosylation of 2B4 is essential for the binding to its ligand CD48.	Nitrogen	91-92	CD48 molecule	Homo sapiens	164-168
17714874-2	2007	RAGE has two N-glycosylation sites in and near the AGE-binding domain, and G82S mutation in the second N-glycosylation motif was recently reported in human.	Nitrogen	13-14	advanced glycosylation end-product specific receptor	Homo sapiens	0-4
17714874-2	2007	RAGE has two N-glycosylation sites in and near the AGE-binding domain, and G82S mutation in the second N-glycosylation motif was recently reported in human.	Nitrogen	103-104	advanced glycosylation end-product specific receptor	Homo sapiens	0-4
17711303-0	2007	N-Glycosylation of the human kappa opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway.	Nitrogen	0-1	opioid receptor kappa 1	Homo sapiens	29-50
17711303-12	2007	Thus, N-glycosylation of the hKOR plays important roles in stability and trafficking along the biosynthesis pathway of the receptor protein as well as agonist-induced receptor regulation.	Nitrogen	6-7	opioid receptor kappa 1	Homo sapiens	29-33
17640631-7	2007	We also show that the nitrogen-containing bisphosphonate-induced effects on p38 phosphorylation occur before accumulation of unprenylated Rap1A or Rac1 activation.	Nitrogen	22-30	Rac family small GTPase 1	Homo sapiens	147-151
21530243-6	2011	Consistent nitrogen removal was achieved for more than 250 days with a maximum nitrogen removal rate of 15.0 kg-TNm(-3)day(-1).	Nitrogen	11-19	teneurin transmembrane protein 1	Homo sapiens	112-115
21530243-6	2011	Consistent nitrogen removal was achieved for more than 250 days with a maximum nitrogen removal rate of 15.0 kg-TNm(-3)day(-1).	Nitrogen	79-87	teneurin transmembrane protein 1	Homo sapiens	112-115
21228891-2	2011	Because of the important role the ammonia-oxidizing bacteria (AOB) and archaea (AOA) have in nitrogen cycling and nitrate leaching, we explored the spatial distribution of their activity, abundance and community composition across a 44-ha large farm divided into an organic and an integrated farming system.	Nitrogen	93-101	aprataxin	Homo sapiens	80-83
22952687-3	2012	The expressions of most nitrogen metabolism related proteins (e.g. Gdh1p, Met1p) were higher in the parental yeast, indicating that the tolerant yeast decreases its nitrogen metabolism rate to reserve energy, and possesses high resistance to the stress of combined inhibitors.	Nitrogen	24-32	uroporphyrinogen-III C-methyltransferase	Saccharomyces cerevisiae S288C	74-79
22039046-0	2011	Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine.	Nitrogen	0-8	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	34-38
21615101-1	2011	5-tert-Butoxycarbonylamino-5-carbethoxy-2-tert-butyldimethylsilyloxy-cyclopentadiene undergoes a Diels-Alder reaction exclusively from the face syn to the nitrogen functionality.	Nitrogen	155-163	synemin	Homo sapiens	144-147
17676829-3	2007	The SAR results were also supported by the X-ray crystallographic elucidation of the role of the N1 nitrogen and the urea moiety when the benzimidazole-urea compounds were bound to the VEGFR-2 enzyme.	Nitrogen	100-108	kinase insert domain receptor	Homo sapiens	185-192
17672512-5	2007	The kinetic specificity constants ( k cat/ K m) for N-acetylation of arylamine environmental contaminants, some of which are associated with bladder cancer risk, were determined with NAT2 and NAT1.	Nitrogen	52-53	N-acetyltransferase 2	Homo sapiens	183-187
17576805-9	2007	Relative contributions of human CYP1A2, CYP2C19, and CYP3A4 to hepatic diuron N-demethylation, based on average abundances of P450 enzymes in human liver microsomes, were approximately 60, 14, and 13%, respectively.	Nitrogen	78-79	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	40-47
21449552-7	2011	We also devised a method for N-acylating proteins in vitro and used it to modify GCAP1 with acyl moieties of different lengths.	Nitrogen	29-30	guanylate cyclase activator 1A	Bos taurus	81-86
22039046-8	2011	PP2A, although not always required for nuclear GATA factor localization, is highly required for GATA factor binding to nitrogen-responsive promoters and subsequent transcription irrespective of the gene GATA factor specificities.	Nitrogen	119-127	protein phosphatase 2 phosphatase activator	Homo sapiens	0-4
17636946-4	2007	The deleterious effects on inhibitor potency by methylation of the anilino-triazole nitrogens, as well as the X-ray crystal structure of triazole 102 bound in the active site of MetAP2, confirm the key interactions between the triazole nitrogens, the active site cobalt atoms, and the His-231 side-chain.	Nitrogen	84-93	methionyl aminopeptidase 2	Homo sapiens	178-184
17636946-4	2007	The deleterious effects on inhibitor potency by methylation of the anilino-triazole nitrogens, as well as the X-ray crystal structure of triazole 102 bound in the active site of MetAP2, confirm the key interactions between the triazole nitrogens, the active site cobalt atoms, and the His-231 side-chain.	Nitrogen	236-245	methionyl aminopeptidase 2	Homo sapiens	178-184
22039046-8	2011	PP2A, although not always required for nuclear GATA factor localization, is highly required for GATA factor binding to nitrogen-responsive promoters and subsequent transcription irrespective of the gene GATA factor specificities.	Nitrogen	119-127	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	96-100
22039046-8	2011	PP2A, although not always required for nuclear GATA factor localization, is highly required for GATA factor binding to nitrogen-responsive promoters and subsequent transcription irrespective of the gene GATA factor specificities.	Nitrogen	119-127	glutaminyl-tRNA amidotransferase subunit QRSL1	Homo sapiens	96-100
21414781-2	2011	In general, reported CRF(1) receptor antagonists possess a sp(2)-nitrogen atom as hydrogen bonding acceptor (HBA) on their core scaffolds.	Nitrogen	65-73	corticotropin releasing hormone receptor 1	Mus musculus	21-36
22026405-2	2011	Owing to the different N-substituted imide groups at the naphthalimide units, the thermal bleaching rate of Nip2 bearing phenyl on the naphthalimide unit is found to be approximately 2 times that of Nip1 bearing n-butyl, indicating that the photochromic properties can be modulated with introduction of different functional groups on the naphthalimide unit.	Nitrogen	23-24	BCL2 interacting protein 2	Homo sapiens	108-112
21414781-3	2011	We proposed to use a carbonyl group of pyrrolo[2,3-d]pyrimidin-4-one derivatives as a replacement for the sp(2)-nitrogen atom as HBA in classical CRF(1) receptor antagonists.	Nitrogen	112-120	corticotropin releasing hormone receptor 1	Mus musculus	146-161
17659281-5	2007	These results indicate that OTR may have a role in the biological nitrogen cycle.	Nitrogen	66-74	tetrathionate reductase family octaheme c-type cytochrome	Shewanella oneidensis MR-1	28-31
22026405-2	2011	Owing to the different N-substituted imide groups at the naphthalimide units, the thermal bleaching rate of Nip2 bearing phenyl on the naphthalimide unit is found to be approximately 2 times that of Nip1 bearing n-butyl, indicating that the photochromic properties can be modulated with introduction of different functional groups on the naphthalimide unit.	Nitrogen	23-24	BCL2 interacting protein 1	Homo sapiens	199-203
21355583-3	2011	In this work, films of ceramides N-acylated with the saturated fatty acids C10, C12, C14, and C16 were studied at the air-aqueous interface.	Nitrogen	33-34	chromosome 12 open reading frame 57	Homo sapiens	75-78
22295784-4	2011	The strength of the frontier fluorescence emission peak became weaker and weaker, and at last disappeared with the enhancement of the ratio of Cd2+ to PAMAM; the strength of the latter fluorescence emission peak became stronger, which indicates that the electron at valence band of N atom in amines of dendrimers was transferred to CdS QDs.	Nitrogen	282-283	CD2 molecule	Homo sapiens	143-146
21237288-6	2011	The nitrogen-containing bisphosphonates pamidronate and zoledronate specifically inhibit farnesyl pyrophosphate synthase indicated by the accumulation of IPP/DMAPP.	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	89-120
21161333-11	2011	These data suggest that NS causes reduced-vasodilation in both eNOS(+/+) and eNOS(-/-) via sEH and CYP4A.	Nitrogen	24-26	epoxide hydrolase 2, cytoplasmic	Mus musculus	91-94
21161333-11	2011	These data suggest that NS causes reduced-vasodilation in both eNOS(+/+) and eNOS(-/-) via sEH and CYP4A.	Nitrogen	24-26	cytochrome P450, family 4, subfamily a, polypeptide 10	Mus musculus	99-104
17500542-0	2007	Epitaxial growth of InN films by molecular-beam epitaxy using hydrazoic acid (HN3) as an efficient nitrogen source.	Nitrogen	99-107	MT-RNR2 like 3 (pseudogene)	Homo sapiens	78-81
17500542-1	2007	Epitaxial InN films have been successfully grown on c-plane GaN template by gas-source molecular-beam epitaxy with hydrazoic acid (HN3) as an efficient nitrogen source.	Nitrogen	152-160	MT-RNR2 like 3 (pseudogene)	Homo sapiens	131-134
17500542-2	2007	Results in residual-gas analyzer show that the HN3 is highly dissociated to produce nitrogen radicals and can be controlled in the amounts of active nitrogen species by tuning HN3 pressure.	Nitrogen	84-92	MT-RNR2 like 3 (pseudogene)	Homo sapiens	47-50
17500542-2	2007	Results in residual-gas analyzer show that the HN3 is highly dissociated to produce nitrogen radicals and can be controlled in the amounts of active nitrogen species by tuning HN3 pressure.	Nitrogen	149-157	MT-RNR2 like 3 (pseudogene)	Homo sapiens	47-50
17500542-2	2007	Results in residual-gas analyzer show that the HN3 is highly dissociated to produce nitrogen radicals and can be controlled in the amounts of active nitrogen species by tuning HN3 pressure.	Nitrogen	149-157	MT-RNR2 like 3 (pseudogene)	Homo sapiens	176-179
17331556-0	2007	The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity.	Nitrogen	12-13	C-X-C motif chemokine receptor 4	Homo sapiens	41-46
17331556-6	2007	Since CXCR4 N-glycans play a less important role in viral entry compared to the N-glycans on the HIV envelope, cells expressing CXCR4 N-glycosylation mutants might be no relevant alternative to allow HIV-1 escape from antivirals.	Nitrogen	12-13	C-X-C motif chemokine receptor 4	Homo sapiens	6-11
21188626-6	2011	The sequence analysis showed two amino acid deletions and loss of an N-glycosylation site in transmissible gastroenteritis virus S protein after passages in piglets.	Nitrogen	69-70	vitronectin	Homo sapiens	129-138
21787278-1	2011	A series of novel compounds with N-phosphoryl peptide modification at the C-4 position on podophyllotoxin were synthesized and evaluated for their cytotoxicity in vitro against K562 cell lines.	Nitrogen	33-34	complement C4A (Rodgers blood group)	Homo sapiens	74-77
20483878-6	2011	Keratin hydrolysate is distinct for its high nitrogen content and reasonable inorganic solids level.	Nitrogen	45-53	keratin	Gallus gallus	0-7
17252314-9	2007	On the other hand, arginase activity and the expression of the stress response gene ACA1 are useful to monitor nitrogen depletion/addition during growth of the wine yeast considered under our vinification conditions.	Nitrogen	111-119	Aca1p	Saccharomyces cerevisiae S288C	84-88
21303349-2	2011	Similarly reactive oxygen/nitrogen species (ROS/RNS) produced during normal metabolic activities, specifically oxidative phosphorylation of the cell, are scavenged by antioxidant enzymes like superoxide dismutase (SOD), catalase but impaired metabolic pathways tend to generate elevated levels of these ROS/RNS.	Nitrogen	26-34	FAM20C golgi associated secretory pathway kinase	Homo sapiens	48-51
17466543-4	2007	The Pklr(G338D) mutation of the CBA/N-Pk(slc) mutant is shown to be more deleterious than the Pklr(I90N) allele with respect to enzymatic activity and severity of hemolytic anemia, with a more dramatic reduction in the half-life of erythrocytes (increased turnover) in the CBA/N-Pk(slc) mice.	Nitrogen	36-37	pyruvate kinase liver and red blood cell	Mus musculus	4-8
17466543-4	2007	The Pklr(G338D) mutation of the CBA/N-Pk(slc) mutant is shown to be more deleterious than the Pklr(I90N) allele with respect to enzymatic activity and severity of hemolytic anemia, with a more dramatic reduction in the half-life of erythrocytes (increased turnover) in the CBA/N-Pk(slc) mice.	Nitrogen	102-103	pyruvate kinase liver and red blood cell	Mus musculus	4-8
21295283-4	2011	DHDDS is a highly conserved essential enzyme for dolichol synthesis, permitting global N-linked glycosylation.	Nitrogen	87-88	dehydrodolichyl diphosphate synthase	Danio rerio	0-5
21303349-2	2011	Similarly reactive oxygen/nitrogen species (ROS/RNS) produced during normal metabolic activities, specifically oxidative phosphorylation of the cell, are scavenged by antioxidant enzymes like superoxide dismutase (SOD), catalase but impaired metabolic pathways tend to generate elevated levels of these ROS/RNS.	Nitrogen	26-34	FAM20C golgi associated secretory pathway kinase	Homo sapiens	307-310
21522316-1	2011	In the title compound, C(9)H(10)ClNO(3)S, the amide H atom is syn with respect to the ortho-methyl group in the benzene ring and the C-S-N-C torsion angle is -66.9 (2) .	Nitrogen	34-35	synemin	Homo sapiens	62-65
22023129-7	2011	For all 3 species, inhibitors of CYP3A4, CYP2A6, CYP2C19, CYP2B6, and CYP2C9 diminished N-demethylation of ketamine.	Nitrogen	88-89	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	70-76
21144611-8	2011	Serum chemerin was positively correlated with age, body mass index (BMI), systolic blood pressure (SBP), C-reactive protein (CRP), blood urea nitrogen (BUN), serum creatinine and serum triglycerides, and negatively correlated with creatinine clearance Stepwise regression analysis showed that creatinine clearance and serum creatinine remained significantly associated with serum chemerin.	Nitrogen	142-150	retinoic acid receptor responder 2	Homo sapiens	6-14
17547741-5	2007	Coexpression of WTNef, or the non-N-myristoylated mutant NefG2A, restored virus yields to levels obtained in the absence of exogenous EED protein.	Nitrogen	18-19	embryonic ectoderm development	Homo sapiens	134-137
21515584-6	2011	Finally, as both FucTA and FUT-1 were shown to be N-glycosylated, we examined the putative N-glycosylation sites.	Nitrogen	50-51	fucosyltransferase 11	Arabidopsis thaliana	17-22
17552775-3	2007	Using this cross-relaxation rate, in addition to hydrogen and nitrogen autorelaxation rates, expressions governing spin-1/2 and spin-1 spin-lattice relaxation are determined.	Nitrogen	62-70	spindlin 1	Homo sapiens	115-121
17552775-4	2007	With ammonium nitrate, containing nitrogen (spin-1) and hydrogen (spin-1/2), increased nitrogen signal and spin-lattice relaxation are demonstrated, using fields less than 120 G. The cross-relaxation rate is also measured and an overall signal/noise improvement by a factor of 2.3+/-0.1 is attained.	Nitrogen	87-95	spindlin 1	Homo sapiens	44-50
17552775-4	2007	With ammonium nitrate, containing nitrogen (spin-1) and hydrogen (spin-1/2), increased nitrogen signal and spin-lattice relaxation are demonstrated, using fields less than 120 G. The cross-relaxation rate is also measured and an overall signal/noise improvement by a factor of 2.3+/-0.1 is attained.	Nitrogen	87-95	spindlin 1	Homo sapiens	66-74
21132432-7	2011	Second, gene expression of AOX is suppressed when N is predominately available as nitrate instead of ammonium.	Nitrogen	50-51	acyl-CoA oxidase 1	Homo sapiens	27-30
21515584-6	2011	Finally, as both FucTA and FUT-1 were shown to be N-glycosylated, we examined the putative N-glycosylation sites.	Nitrogen	50-51	fucosyltransferase 1 (H blood group)	Homo sapiens	27-32
21515584-7	2011	While alanine replacements at single potential N-glycosylation sites of FucTA resulted in a loss of up to 80% of the activity, a triple glycosylation site mutant still retained 5%, as compared to the control.	Nitrogen	47-48	fucosyltransferase 11	Arabidopsis thaliana	72-77
17192600-0	2007	Cytoskeleton vimentin disruption of mouse sertoli cells injured by nitrogen mustard in vitro.	Nitrogen	67-75	vimentin	Mus musculus	13-21
21816953-2	2011	DTIC is activated by CYP1A1 and CYP1A2 catalyzed N-demethylation.	Nitrogen	49-50	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	21-27
17462576-5	2007	An ability to identify resonances from active site residues and produce distance constraints is illustrated on a (15)N phenylalanine-labeled version of the structurally uncharacterized, alpha-2,6-linked sialyltransferase, ST6Gal I.	Nitrogen	117-118	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	222-230
21816953-2	2011	DTIC is activated by CYP1A1 and CYP1A2 catalyzed N-demethylation.	Nitrogen	49-50	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	32-38
21816953-9	2011	DTIC N-demethylation by the E161K, E256K, and I458V mutants exhibited Michaelis-Menten kinetics, with decreases in K(m) (183-249 muM) that doubled the catalytic efficiency (p &lt; 0.05) relative to wild-type CYP1A1 (K(m), 408 +- 43 muM; V(max), 28 +- 4 pmol   min(-1)   pmol of P450(-1)).	Nitrogen	5-6	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	208-214
21918191-7	2011	Septic CD73 KO mice had higher blood urea nitrogen levels and increased cytokine levels in the kidney, indicating increased renal dysfunction.	Nitrogen	42-50	5' nucleotidase, ecto	Mus musculus	7-11
17381748-2	2007	METHODS AND RESULTS: Carbon and nitrogen sources and growth factors, such as amino acids and vitamins, were screened initially in a mineral medium for the biomass and antagonistic compound of Pseudomonas MCCB 103.	Nitrogen	32-40	methylcrotonyl-CoA carboxylase subunit 2	Homo sapiens	204-208
17259447-3	2007	N-Demethylation of methadone in vitro is predominantly mediated by cytochrome P450 CYP3A4 and CYP2B6 and somewhat by CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	117-124
17259447-4	2007	This investigation evaluated stereoselectivity, models, and kinetic parameters for methadone N-demethylation by recombinant CYP2B6, CYP3A4, and CYP2C19, and the potential for interactions between enantiomers during racemate metabolism.	Nitrogen	93-94	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	144-151
21854074-4	2011	Aiming for the development of potent, selective, and less lipophilic FFA1 agonists, the terminal phenyl of a known compound series was replaced by nitrogen containing heterocycles.	Nitrogen	147-155	free fatty acid receptor 1	Homo sapiens	69-73
17493133-0	2007	The yeast ammonium transport protein Mep2 and its positive regulator, the Npr1 kinase, play an important role in normal and pseudohyphal growth on various nitrogen media through retrieval of excreted ammonium.	Nitrogen	155-163	ammonium permease MEP2	Saccharomyces cerevisiae S288C	37-41
17493133-0	2007	The yeast ammonium transport protein Mep2 and its positive regulator, the Npr1 kinase, play an important role in normal and pseudohyphal growth on various nitrogen media through retrieval of excreted ammonium.	Nitrogen	155-163	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	74-78
17493133-4	2007	We show here that the growth impairment of cells lacking Npr1 on many nitrogen sources is shared by cells deprived of the three Mep proteins and is a consequence of deficient ammonium retrieval.	Nitrogen	70-78	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	57-61
17493133-5	2007	Expression of a newly isolated Npr1-independent and hyperactive Mep2 in cells lacking Npr1 and/or the Mep proteins restores growth on low ammonium but also on other nitrogen sources.	Nitrogen	165-173	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	31-35
21750110-1	2011	Heterozygosity for mutations (N88S and P90L) in the N-glycosylation site of seipin/BSCL2 is associated with the autosomal dominant motor neuron diseases, spastic paraplegia 17 and distal hereditary motor neuropathy type V, referred to as "seipinopathies".	Nitrogen	30-31	Berardinelli-Seip congenital lipodystrophy 2 (seipin)	Mus musculus	76-82
17493133-5	2007	Expression of a newly isolated Npr1-independent and hyperactive Mep2 in cells lacking Npr1 and/or the Mep proteins restores growth on low ammonium but also on other nitrogen sources.	Nitrogen	165-173	ammonium permease MEP2	Saccharomyces cerevisiae S288C	64-68
21750110-1	2011	Heterozygosity for mutations (N88S and P90L) in the N-glycosylation site of seipin/BSCL2 is associated with the autosomal dominant motor neuron diseases, spastic paraplegia 17 and distal hereditary motor neuropathy type V, referred to as "seipinopathies".	Nitrogen	30-31	Berardinelli-Seip congenital lipodystrophy 2 (seipin)	Mus musculus	83-88
16996129-2	2007	Newer nitrogen containing bisphosphonates such as zoledronate act, at least in part, by inhibiting farnesyl diphosphate synthase and subsequent protein prenylation, furthermore, limited data suggests that zoledronate exerts a direct anti-tumour effect against human myeloma cell lines.	Nitrogen	6-14	farnesyl diphosphate synthase	Homo sapiens	99-128
21725556-5	2011	Specifically, nitrogen donor atoms of TTF-PPB adopt a cis-coordination but not in the equatorial plane, which is quite rare.	Nitrogen	14-22	ras homolog family member H	Homo sapiens	38-41
17277961-15	2007	The more active nitrogen containing bisphosphonates inhibit mevalonate metabolism due to the specific inhibition of farnesyl pyrophosphate synthase.	Nitrogen	16-24	farnesyl diphosphate synthase	Homo sapiens	116-147
21793061-5	2011	This reduced electrostatic interaction, and the large interfragment dispersion stabilize the long, heterocationic/anionic multicenter interaction, which in [TTF(delta+)   TCNE(delta-)] always involves two electrons, but have ten, eight, and eight bond critical points (bcps) involving C-C, N-S, and sometimes C-S and C-N components for the alpha, beta, and delta polymorphs, respectively.	Nitrogen	173-174	ras homolog family member H	Homo sapiens	157-160
17270009-3	2007	Nitrogen limitation in Arabidopsis led to a decrease in the chloroplast galactolipid monogalactosyldiacylglycerol (MGDG) and a concomitant increase in digalactosyldiacylglycerol (DGDG), which correlated with an elevated expression of the DGDG synthase genes DGD1 and DGD2.	Nitrogen	0-8	digalactosyl diacylglycerol deficient 2	Arabidopsis thaliana	267-271
21793061-5	2011	This reduced electrostatic interaction, and the large interfragment dispersion stabilize the long, heterocationic/anionic multicenter interaction, which in [TTF(delta+)   TCNE(delta-)] always involves two electrons, but have ten, eight, and eight bond critical points (bcps) involving C-C, N-S, and sometimes C-S and C-N components for the alpha, beta, and delta polymorphs, respectively.	Nitrogen	290-291	ras homolog family member H	Homo sapiens	157-160
21670949-0	2011	Erratum to: N-Glycosylation profiling of recombinant mouse extracellular superoxide dismutase produced in Chinese hamster ovary cells.	Nitrogen	12-13	superoxide dismutase 3, extracellular	Mus musculus	59-93
17221970-3	2007	N-Hydroxylation occurs in the case of the Boc-protected peptides, and side chain hydroxylation takes place in the case of acetyl-protected peptides.	Nitrogen	0-1	BOC cell adhesion associated, oncogene regulated	Homo sapiens	42-45
17230619-16	2007	VEGF mRNA expression was significantly inhibited by N-desulfated heparin and was higher in normal saline group than in N-desulfated heparin group (Ct value 19.51 +/- 1.01 vs 22.55 +/- 1.36, P &lt; 0.05).	Nitrogen	7-8	vascular endothelial growth factor A	Mus musculus	0-4
17160180-1	2007	Reaction of the electron-rich, bulky tridentate PNN ligand (PNN=2-di-tert-butylphosphinomethyl-6-diethylaminomethylpyridine) with Ru(PPh3)3Cl2 at 65 degrees C resulted in formation of the mononuclear dinitrogen complex (PNN)Ru(Cl)2N2 (minor) and the N2 bridged Ru(II) dinuclear complex [(PNN)Ru(Cl)2]2(micro-N2) (major).	Nitrogen	231-233	pinin, desmosome associated protein	Homo sapiens	48-51
17160180-1	2007	Reaction of the electron-rich, bulky tridentate PNN ligand (PNN=2-di-tert-butylphosphinomethyl-6-diethylaminomethylpyridine) with Ru(PPh3)3Cl2 at 65 degrees C resulted in formation of the mononuclear dinitrogen complex (PNN)Ru(Cl)2N2 (minor) and the N2 bridged Ru(II) dinuclear complex [(PNN)Ru(Cl)2]2(micro-N2) (major).	Nitrogen	231-233	pinin, desmosome associated protein	Homo sapiens	60-63
17160180-1	2007	Reaction of the electron-rich, bulky tridentate PNN ligand (PNN=2-di-tert-butylphosphinomethyl-6-diethylaminomethylpyridine) with Ru(PPh3)3Cl2 at 65 degrees C resulted in formation of the mononuclear dinitrogen complex (PNN)Ru(Cl)2N2 (minor) and the N2 bridged Ru(II) dinuclear complex [(PNN)Ru(Cl)2]2(micro-N2) (major).	Nitrogen	231-233	pinin, desmosome associated protein	Homo sapiens	60-63
17160180-1	2007	Reaction of the electron-rich, bulky tridentate PNN ligand (PNN=2-di-tert-butylphosphinomethyl-6-diethylaminomethylpyridine) with Ru(PPh3)3Cl2 at 65 degrees C resulted in formation of the mononuclear dinitrogen complex (PNN)Ru(Cl)2N2 (minor) and the N2 bridged Ru(II) dinuclear complex [(PNN)Ru(Cl)2]2(micro-N2) (major).	Nitrogen	231-233	pinin, desmosome associated protein	Homo sapiens	60-63
17024473-6	2007	Comparison of the partial amino acid sequence of deglycosylated-Hpf2p with the deduced protein sequence of YDR055w, confirmed five of the 15 potential N-linked glycosylation sites in this sequence were occupied.	Nitrogen	151-152	Pst1p	Saccharomyces cerevisiae S288C	64-69
21726770-5	2011	Regardless of the N-derivative of the IDA chelator, molecular recognition between H2AP and the referred Cu(II)-chelates only displays the formation of the Cu-N7(purine-like) bond what is clearly in contrast to what was previously reported for adenine.	Nitrogen	18-19	H2A clustered histone 11	Homo sapiens	82-86
17024473-7	2007	Methylation analysis of the carbohydrate moieties of Hpf2p indicated that this protein contained both N- and O-linked mannose chains.	Nitrogen	102-103	Pst1p	Saccharomyces cerevisiae S288C	53-58
17020955-7	2007	In human liver microsomes, involvement of CYP2D6, CYP1A2, CYP2C9, and CYP2C19 in diphenhydramine N-demethylation was confirmed by using P450 isozyme-specific inhibitors.	Nitrogen	97-98	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	70-77
17200572-7	2007	When TOR is inactivated by rapamycin treatment or nitrogen starvation, downstream effectors of TOR such as the serine/threonine protein kinase NPR1 and the TAP42 interacting protein TIP41 are dephosphorylated in a SIT4-dependent manner.	Nitrogen	50-58	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	143-147
21434773-9	2011	The N-glucuronidation rates in humans are typically much higher than in animals, largely due to the activity of two enzymes, the extensively studied UGT1A4, and the more recently identified as a main player in N-glucuronidation, UGT2B10.	Nitrogen	4-5	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	149-155
18025712-4	2007	Using this assay, we subsequently showed that N-lipid modification is critical for Shh activity in the telencephalon (2).	Nitrogen	46-47	sonic hedgehog signaling molecule	Rattus norvegicus	83-86
21434773-9	2011	The N-glucuronidation rates in humans are typically much higher than in animals, largely due to the activity of two enzymes, the extensively studied UGT1A4, and the more recently identified as a main player in N-glucuronidation, UGT2B10.	Nitrogen	4-5	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	229-236
21434773-9	2011	The N-glucuronidation rates in humans are typically much higher than in animals, largely due to the activity of two enzymes, the extensively studied UGT1A4, and the more recently identified as a main player in N-glucuronidation, UGT2B10.	Nitrogen	210-211	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	149-155
17284458-0	2007	Interplay between CRP-cAMP and PII-Ntr systems forms novel regulatory network between carbon metabolism and nitrogen assimilation in Escherichia coli.	Nitrogen	108-116	catabolite gene activator protein	Escherichia coli	18-21
21434773-9	2011	The N-glucuronidation rates in humans are typically much higher than in animals, largely due to the activity of two enzymes, the extensively studied UGT1A4, and the more recently identified as a main player in N-glucuronidation, UGT2B10.	Nitrogen	210-211	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	229-236
17284458-5	2007	Previous studies suggest that CRP affects nitrogen assimilation.	Nitrogen	42-50	catabolite gene activator protein	Escherichia coli	30-33
21434773-10	2011	We discuss both enzymes and review the findings that revealed the role of UGT2B10 in N-glucuronidation.	Nitrogen	85-86	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	74-81
17284458-10	2007	CRP-induced DNA-bending prevents the nitrogen regulation protein C (NtrC) activator from approaching the activator-accessible face of the promoter-bound Esigma(54) closed complex, and inhibits glnAp2.	Nitrogen	37-45	catabolite gene activator protein	Escherichia coli	0-3
17284458-11	2007	Therefore, as the major transcriptional effector of the "glucose effect", CRP affects both the signal transduction pathway and the overall geometry of the transcriptional machinery of components of the nitrogen regulon.	Nitrogen	202-210	catabolite gene activator protein	Escherichia coli	74-77
21772271-5	2011	Decreased nitrate reductase activity in siz1-2 plants resulted in low nitrogen concentrations, low nitric oxide production and high nitrate content in comparison with wild-type plants.	Nitrogen	70-78	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	40-44
17010621-1	2006	The synthesis of two novel amino acids, nitrogen analogues of the naturally occurring glycosidase inhibitor, salacinol, containing a carboxylate inner salt are described, along with the crystal structure of one of these analogues in the active site of Drosophila melanogaster Golgi mannosidase II (dGMII).	Nitrogen	40-48	alpha-Mannosidase class II a	Drosophila melanogaster	298-303
21772271-8	2011	Our results indicate that AtSIZ1 positively controls nitrogen assimilation by promoting sumoylation of NRs in Arabidopsis.	Nitrogen	53-61	DNA-binding protein with MIZ/SP-RING zinc finger, PHD-finger and SAP domain-containing protein	Arabidopsis thaliana	26-32
21356311-7	2011	In the present work, we over-expressed, purified and characterized two stable isotope-labeled DNA glycosylases, i.e., (15)N-labeled Escherichia coli formamidopyrimidine DNA glycosylase (Fpg) and (15)N-labeled human 8-oxoguanine-DNA glycosylase (hOGG1).	Nitrogen	95-96	8-oxoguanine DNA glycosylase	Homo sapiens	215-243
16962791-6	2006	The recombinant receptor undergoes N-linked glycosylation, tyrosine sulfation and is recognized by the 12G5 conformation specific antibody against human CXCR4.	Nitrogen	35-36	C-X-C motif chemokine receptor 4	Homo sapiens	153-158
17031531-3	2006	(15)N-labeled ubiquitin, its derivatives and calmodulin were injected into Xenopus oocytes and two-dimensional (1)H-(15)N correlation spectra of the proteins were obtained.	Nitrogen	4-5	ubiquitin B S homeolog	Xenopus laevis	14-23
21356311-7	2011	In the present work, we over-expressed, purified and characterized two stable isotope-labeled DNA glycosylases, i.e., (15)N-labeled Escherichia coli formamidopyrimidine DNA glycosylase (Fpg) and (15)N-labeled human 8-oxoguanine-DNA glycosylase (hOGG1).	Nitrogen	95-96	8-oxoguanine DNA glycosylase	Homo sapiens	245-250
21356311-7	2011	In the present work, we over-expressed, purified and characterized two stable isotope-labeled DNA glycosylases, i.e., (15)N-labeled Escherichia coli formamidopyrimidine DNA glycosylase (Fpg) and (15)N-labeled human 8-oxoguanine-DNA glycosylase (hOGG1).	Nitrogen	122-123	8-oxoguanine DNA glycosylase	Homo sapiens	215-243
21356311-7	2011	In the present work, we over-expressed, purified and characterized two stable isotope-labeled DNA glycosylases, i.e., (15)N-labeled Escherichia coli formamidopyrimidine DNA glycosylase (Fpg) and (15)N-labeled human 8-oxoguanine-DNA glycosylase (hOGG1).	Nitrogen	122-123	8-oxoguanine DNA glycosylase	Homo sapiens	245-250
17004712-8	2006	To determine whether the carboxamide oxygen or the piperidine nitrogen of the C-3 substituent may be the interaction site for K3.28(192), we designed, synthesized, and evaluated a new set of analogues of 1 (3-6, Chart 1) in which modifications only to the C-3 substituent of 1 have been made.	Nitrogen	62-70	complement C3	Homo sapiens	78-81
16864577-7	2006	If Npr1 functions directly, then the ability of all good nitrogen sources to restrict Gln3 to the cytoplasm should be lost in an npr1Delta just as occurs when URE2 (encoding this well studied negative Gln3 regulator) is deleted.	Nitrogen	57-65	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	3-7
21300106-9	2011	We concluded that the STT3-B/STT3-A ratio modulates the N-glycosylation level of IgG, in agreement with previous data showing that full N-glycosylation of polypeptides requires cooperation between both catalytic isoforms.	Nitrogen	56-57	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	22-28
16951347-9	2006	As shown for humans, the mAb 3G8 was able to block IgG binding to nonhuman primate CD16 and inhibition of nonhuman primate CD16 N-glycosylation enhanced IgG binding.	Nitrogen	128-129	Fc gamma receptor IIIa	Homo sapiens	123-127
16956297-4	2006	Moreover, nitrogen-containing bisphosphonates have been proposed as carbocation transition state analogues of FPPS.	Nitrogen	10-18	farnesyl diphosphate synthase	Homo sapiens	110-114
21300106-9	2011	We concluded that the STT3-B/STT3-A ratio modulates the N-glycosylation level of IgG, in agreement with previous data showing that full N-glycosylation of polypeptides requires cooperation between both catalytic isoforms.	Nitrogen	56-57	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	29-35
21300106-9	2011	We concluded that the STT3-B/STT3-A ratio modulates the N-glycosylation level of IgG, in agreement with previous data showing that full N-glycosylation of polypeptides requires cooperation between both catalytic isoforms.	Nitrogen	136-137	STT3 oligosaccharyltransferase complex catalytic subunit B	Homo sapiens	22-28
21300106-9	2011	We concluded that the STT3-B/STT3-A ratio modulates the N-glycosylation level of IgG, in agreement with previous data showing that full N-glycosylation of polypeptides requires cooperation between both catalytic isoforms.	Nitrogen	136-137	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	29-35
16939284-2	2006	Upon addition of the cis form of 1,2-bispyridylethylene (cis-2) to (+)-1 ([cis-2]/[(+)-1] = 5.0), an enantiomer of 1, the intramolecular Zn-N coordination bonds in (+)-1 are readily cleaved to form an externally locked, cyclodimeric one-to-one complex (+)-1 subset cis-2, accompanying a rotation of the ferrocene module, as visualized by CD spectroscopy.	Nitrogen	140-141	suppressor of cytokine signaling 2	Homo sapiens	57-62
21784315-2	2011	Modification of the heme moiety of LPO by nitrogen-containing compounds has been shown to inactivate LPO.	Nitrogen	42-50	lactoperoxidase	Bos taurus	35-38
16783472-8	2006	However, inclusion of n-3 PUFA in the diet (HF/3) completely prevented macrophage infiltration induced by high-fat diet and changes in inflammatory gene expression, also tending to reduce JNK phosphorylation (p&lt;0.1) in diabetic mice despite unreduced body weight.	Nitrogen	10-11	mitogen-activated protein kinase 8	Mus musculus	188-191
21784315-2	2011	Modification of the heme moiety of LPO by nitrogen-containing compounds has been shown to inactivate LPO.	Nitrogen	42-50	lactoperoxidase	Bos taurus	101-104
21276281-10	2011	Rats fed the 5 % n-3 PUFA diet had lower (58 2 %; P &lt; 0 01) enterocytic phosphorylated JNK protein and secreted less cholesterol (30 %; P &lt; 0 05) into mesenteric lymph compared with the control.	Nitrogen	17-18	mitogen-activated protein kinase 8	Rattus norvegicus	90-93
16989530-3	2006	In both cases, the first four conformers showed the N-Me group in the syn orientation, permitting the formation of a hydrogen bond between the hydroxy group at the tropane ring and the tertiary nitrogen atom.	Nitrogen	194-202	synemin	Homo sapiens	70-73
21071054-3	2011	In contrast, basic amino acid substitutions at position 25, or substitutions at positions 6-8 resulting in the loss of a potential N-linked glycosylation site, contributed to CXCR4-mediated entry but required additional substitutions acting cooperatively to confer efficient CXCR4 use.	Nitrogen	131-132	C-X-C motif chemokine receptor 4	Homo sapiens	175-180
21561822-5	2011	Two human LPL N-glycosylation sites were conserved among seven predicted sites for the vertebrate LPL sequences examined.	Nitrogen	14-15	lipoprotein lipase	Homo sapiens	10-13
21404688-2	2011	The results indicated that TSBMBR owned advantages of SBR in removing nitrogen and phosphorous, which could make up the deficiency of traditional one-stage aerobic MBR in nitrogen and phosphorous removal.	Nitrogen	70-78	translocator protein	Homo sapiens	30-33
21404688-2	2011	The results indicated that TSBMBR owned advantages of SBR in removing nitrogen and phosphorous, which could make up the deficiency of traditional one-stage aerobic MBR in nitrogen and phosphorous removal.	Nitrogen	171-179	translocator protein	Homo sapiens	30-33
22194972-3	2011	METHODOLOGY/PRINCIPAL FINDINGS: Full-length THSD7A was overexpressed in human embryonic kidney 293T (HEK293T) cells and was found to be membrane associated and N-glycosylated.	Nitrogen	15-16	thrombospondin type 1 domain containing 7A	Homo sapiens	44-50
21912684-2	2011	The Gap1 general amino acid permease and the Mep2 ammonium permease mediate rapid activation by amino acids and by ammonium, respectively, of the protein kinase A (PKA) pathway in nitrogen-starved cells.	Nitrogen	180-188	ammonium permease MEP2	Saccharomyces cerevisiae S288C	45-49
20446811-5	2011	Our results revealed that serum creatinine and urea nitrogen levels decreased to the baseline more quickly in HGF-hucMSCs-treated group than that in hucMSCs- or green fluorescent protein-hucMSCs-treated groups at 72 h after injury.	Nitrogen	52-60	hepatocyte growth factor	Rattus norvegicus	110-113
16880608-7	2006	In this paper, using various glycosylation consensus sequence mutants, we demonstrated that the N-linked glycosylation of Dectin-1 affects the cell surface expression of the molecule.	Nitrogen	96-97	C-type lectin domain family 7, member a	Mus musculus	122-130
16880608-9	2006	These results suggest that N-linked glycosylation on Dectin-1 is essential for the recognition of fungal beta-glucan and subsequent activation of NF-kappaB.	Nitrogen	27-28	C-type lectin domain family 7, member a	Mus musculus	53-61
16798095-9	2006	All these findings led us to conclude that interactions between N-SH3 of p47phox and PPII helix, which is formed by cytoplasmic region of p22phox, may play a significant role in the activation of the NADPH oxidase.	Nitrogen	64-65	neutrophil cytosolic factor 1	Homo sapiens	73-80
16872554-9	2006	The observed changes indicate an impairment of N-deethylation metabolic pathway in streptozotocin-induced diabetic rats, i.e. a possible decrease in the enzymatic activity of CYP3A2 and CYP1A2.	Nitrogen	47-48	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	186-192
16545961-6	2006	We have successfully produced and isolated (15)N-labeled INGAPrP by expression in Escherichia coli Rosetta (DE3) cells in Spectra-9 media followed by a two-step purification and refolding protocol.	Nitrogen	47-48	regenerating islet-derived 3 delta	Mus musculus	57-64
16690312-2	2006	SAR on the electron-induced effects of various linkers as well as substituents on the phenyl rings and the piperidine nitrogen has been investigated.	Nitrogen	118-126	sarcosine dehydrogenase	Homo sapiens	0-3
16821835-11	2006	This is a very large bonding energy, much larger than has previously been obtained for no-pair clusters of lithium, BDE/n = 12 kcal mol(-1), or sodium clusters, BDE/n = 3 kcal mol(-1).	Nitrogen	23-24	homeobox D13	Homo sapiens	116-119
16821835-11	2006	This is a very large bonding energy, much larger than has previously been obtained for no-pair clusters of lithium, BDE/n = 12 kcal mol(-1), or sodium clusters, BDE/n = 3 kcal mol(-1).	Nitrogen	23-24	homeobox D13	Homo sapiens	161-164
16821835-11	2006	This is a very large bonding energy, much larger than has previously been obtained for no-pair clusters of lithium, BDE/n = 12 kcal mol(-1), or sodium clusters, BDE/n = 3 kcal mol(-1).	Nitrogen	26-27	homeobox D13	Homo sapiens	116-119
16821835-11	2006	This is a very large bonding energy, much larger than has previously been obtained for no-pair clusters of lithium, BDE/n = 12 kcal mol(-1), or sodium clusters, BDE/n = 3 kcal mol(-1).	Nitrogen	26-27	homeobox D13	Homo sapiens	161-164
16624901-4	2006	In this study we analyzed the gene expression profile on a genomewide scale and found that deletion of either tsc1(+) or tsc2(+) affects gene induction upon nitrogen starvation.	Nitrogen	157-165	TSC complex subunit 2	Homo sapiens	121-125
16563432-12	2006	These results suggest that the N-glyco side-chain of AMFR is a trigger and that interaction between the 117-C-terminal part of AMF and the extracellular core protein of AMFR is needed during AMF-AMFR interactions.	Nitrogen	31-32	autocrine motility factor receptor	Homo sapiens	53-57
16563432-12	2006	These results suggest that the N-glyco side-chain of AMFR is a trigger and that interaction between the 117-C-terminal part of AMF and the extracellular core protein of AMFR is needed during AMF-AMFR interactions.	Nitrogen	31-32	autocrine motility factor receptor	Homo sapiens	169-173
16563432-12	2006	These results suggest that the N-glyco side-chain of AMFR is a trigger and that interaction between the 117-C-terminal part of AMF and the extracellular core protein of AMFR is needed during AMF-AMFR interactions.	Nitrogen	31-32	autocrine motility factor receptor	Homo sapiens	169-173
16364638-2	2006	SAR studies for the N-alkyl-azadienoic acids described here demonstrate that the RXR activity profile is sensitive to the N-alkyl chain length.	Nitrogen	20-21	sarcosine dehydrogenase	Homo sapiens	0-3
16364638-2	2006	SAR studies for the N-alkyl-azadienoic acids described here demonstrate that the RXR activity profile is sensitive to the N-alkyl chain length.	Nitrogen	20-21	retinoid X receptor alpha	Homo sapiens	81-84
16402080-1	2006	Retigabine (RGB) is an investigational antiepileptic drug, which undergoes extensive UGT1A1, 1A9 and 1A4-mediated N-glucuronidation and N-acetylation.	Nitrogen	114-115	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	85-91
16469746-8	2006	SPACRCAN had heavily sialylated N- and O-linked glycoconjugates, and its MY-174 antigenicity was abolished by O-glycanase treatment after neuraminidase treatment, as observed for chick SPACR.	Nitrogen	7-8	interphotoreceptor matrix proteoglycan 1	Gallus gallus	0-5
16789430-3	2006	Berberine was found to readily fit within the binding pocket of h-PTP 1B in a low energy orientation characterized with optimal electrostatic attractive interactions bridging the isoquinolinium positively charged nitrogen atom of berberine and the negatively charged acidic residue of ASP 48 of h-PTP 1B.	Nitrogen	213-221	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	66-72
16604055-11	2006	On Western blots, choroidal ICAM-1 exhibited a greater molecular weight than the retinal form, with most of the apparent weight difference due to N-linked carbohydrate chains.	Nitrogen	146-147	intercellular adhesion molecule 1	Homo sapiens	28-34
16517958-14	2006	CONCLUSIONS: These data demonstrate that NAC is available as a precursor for CYS to support growth and protein (nitrogen) accretion in piglets administered a parenteral solution.	Nitrogen	112-120	X-linked Kx blood group	Homo sapiens	41-44
16468990-4	2006	In nitrogen-starved cells, ammonium transport and activation of trehalase are most active in strains expressing either the Mep2 or Mep1 ammonium permease, as opposed to Mep3.	Nitrogen	3-11	ammonium permease MEP2	Saccharomyces cerevisiae S288C	123-127
16289184-6	2006	Analysis of env N-linked glycosylation sites revealed fewer sites in the V1 region of envelope compared to other subtype A.	Nitrogen	16-17	endogenous retrovirus group K member 20	Homo sapiens	12-15
16492559-3	2006	Biochemical and crystallographic data suggest that p35-N circularization results from the trapping of a native chemical ligation intermediate in the p35/caspase complex, in which the N-terminal Cys2 of p35 attacks the Asp87-Cys360" thioester to form an equilibrium between Asp87-Cys2 and Asp87-Cys360".	Nitrogen	55-56	interleukin 12A	Homo sapiens	51-54
16492559-3	2006	Biochemical and crystallographic data suggest that p35-N circularization results from the trapping of a native chemical ligation intermediate in the p35/caspase complex, in which the N-terminal Cys2 of p35 attacks the Asp87-Cys360" thioester to form an equilibrium between Asp87-Cys2 and Asp87-Cys360".	Nitrogen	55-56	interleukin 12A	Homo sapiens	149-152
16492559-3	2006	Biochemical and crystallographic data suggest that p35-N circularization results from the trapping of a native chemical ligation intermediate in the p35/caspase complex, in which the N-terminal Cys2 of p35 attacks the Asp87-Cys360" thioester to form an equilibrium between Asp87-Cys2 and Asp87-Cys360".	Nitrogen	55-56	interleukin 12A	Homo sapiens	149-152
16892359-4	2006	Stabilization of the FPPS-N-BP complex through IPP binding is supported by differential scanning calorimetry analyses of a set of representative N-BPs.	Nitrogen	26-27	farnesyl diphosphate synthase	Homo sapiens	21-25
16506518-10	2006	The nitrogen byproducts from the photocatalysis of RDX and HMX were mainly NO3- with NO2-, and NH4+.	Nitrogen	4-12	radixin	Homo sapiens	51-54
16506518-11	2006	The total nitrogen recovery was about 60% from RDX (20 mg l(-1)), and 70% from HMX (5 mg l(-1)), respectively.	Nitrogen	10-18	radixin	Homo sapiens	47-50
16161151-7	2006	Site-by-site mutagenesis of CD47"s five N-linked glycosylation sites progressively decreases expression levels on yeast, but folding appears stable.	Nitrogen	40-41	CD47 molecule	Homo sapiens	28-32
16702020-2	2006	As a result of heterogeneous N-glycosylation, CD147 exists in both highly glycosylated form, HG-CD147 ( approximately 40-60kDa) and lowly glycosylated form, LG-CD147 ( approximately 32kDa).	Nitrogen	29-30	basigin	Mus musculus	46-51
16528972-8	2006	T/N ratios for CB, TSA elevated 2.3-fold, 2.5-fold respectively).	Nitrogen	2-3	cathepsin B	Homo sapiens	15-17
16251720-7	2006	Flow cytometry, immunoblotting, and immunohistochemistry using anti-moesin antibody showed that the HDL/apoA-I binding protein was N-glycosylated and expressed on the cell surface.	Nitrogen	131-132	NAD(P)HX epimerase	Homo sapiens	104-126
16354708-4	2006	Previously, we have shown that proficient and error-free replication through the gamma-HOPdG (gamma-hydroxy-1,N2-propano-2"-deoxyguanosine) adduct, which is formed from the reaction of acrolein with the N2 of guanine, is mediated by the sequential action of human Poliota and Polkappa, in which Poliota incorporates the nucleotide opposite the lesion site and Polkappa carries out the subsequent extension reaction.	Nitrogen	110-112	DNA polymerase lambda	Homo sapiens	360-368
16714119-2	2006	We recently demonstrated that N-methylation and N-acetylation of Lys/Hyl amino group did not significantly alter the thermal stability of the triple helical conformation and that the binding of modified collagens I and II to decorin is lost only on N-acetylation.	Nitrogen	48-49	megakaryocyte-associated tyrosine kinase	Homo sapiens	69-72
16714119-2	2006	We recently demonstrated that N-methylation and N-acetylation of Lys/Hyl amino group did not significantly alter the thermal stability of the triple helical conformation and that the binding of modified collagens I and II to decorin is lost only on N-acetylation.	Nitrogen	48-49	megakaryocyte-associated tyrosine kinase	Homo sapiens	69-72
16714119-3	2006	The positive charge at physiological pH of Lys/Hyl side chains is preserved only by N-methylation.	Nitrogen	84-85	megakaryocyte-associated tyrosine kinase	Homo sapiens	47-50
16714119-6	2006	N-acetylation blocks the formation of banded fibrils in neutral conditions (as did all other chemical modifications reported in the literature), demonstrating that the positive charge of Lys/Hyl amino groups is essential for self-aggregation.	Nitrogen	0-1	megakaryocyte-associated tyrosine kinase	Homo sapiens	191-194
15979880-4	2005	A 60% increase in the amount of more acidic isoforms of GFAP was observed in AD and these isoforms were both phosphorylated and N-glycosylated, while more basic isoforms were O-glycosylated and exhibited no quantitative differences between post-mortem AD and control brains.	Nitrogen	128-129	glial fibrillary acidic protein	Homo sapiens	56-60
16133214-1	2005	The PII signal transducing protein is involved in carbon/nitrogen (C/N) sensing in bacteria and cyanobacteria.	Nitrogen	57-65	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	4-7
16133214-1	2005	The PII signal transducing protein is involved in carbon/nitrogen (C/N) sensing in bacteria and cyanobacteria.	Nitrogen	69-70	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	4-7
16133214-9	2005	Furthermore, when grown hydroponically, the PII mutants displayed a slight increase in carbohydrate (starch and sugars) levels in response to N starvation and a slight decrease in the levels of ammonium (NH (4) (+) ) and amino acids (mainly Gln) in response to NH (4) (+) resupply.	Nitrogen	142-143	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	44-47
16133214-10	2005	Although the phenotypic changes are rather small in the mutant lines, these data support the hypothesis of a subtle involvement of the PII protein in the regulation of some steps of primary C and N metabolism.	Nitrogen	196-197	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	135-138
16268524-2	2005	These sulfones 1 behave as N-(Boc)-protected nitrones 4 in the reaction with organometallics to give N-(Boc)hydroxylamines.	Nitrogen	27-28	BOC cell adhesion associated, oncogene regulated	Homo sapiens	30-33
16268524-2	2005	These sulfones 1 behave as N-(Boc)-protected nitrones 4 in the reaction with organometallics to give N-(Boc)hydroxylamines.	Nitrogen	27-28	BOC cell adhesion associated, oncogene regulated	Homo sapiens	104-107
15994856-6	2005	Similar to what was observed in RMECs, total PKC activity was also stimulated in cerebral microvessels isolated from rats exposed to hypoxia (6% O2-94% N2; 1 h) and posthypoxic reoxygenation (room air; 10 min).	Nitrogen	152-154	protein kinase C, gamma	Rattus norvegicus	45-48
15994856-7	2005	In contrast, hypoxia (6% O2-94% N2; 1 h) and posthypoxic reoxygenation (room air; 10 min) significantly increased the expression levels of only PKC-gamma and PKC-theta in the in vivo hypoxia model.	Nitrogen	32-34	protein kinase C, gamma	Rattus norvegicus	144-153
16150056-10	2005	In addition, we show that RA and BDNF regulate N-linked glycosylation of APLP1.	Nitrogen	35-36	amyloid beta precursor like protein 1	Homo sapiens	73-78
15804238-7	2005	These results suggest that the TM2-3 region of AE1 may become transiently exposed to the endoplasmic reticulum lumen during biosynthesis, and that there is a competition between proper folding of the region into the membrane and N-glycosylation at introduced sites.	Nitrogen	229-230	tropomyosin 3	Homo sapiens	31-36
15804238-9	2005	As a result, engineered N-glycosylation acceptor sites in TM2-3 could not be utilized by the oligosaccharyltransferase in this mutant form of AE1.	Nitrogen	24-25	tropomyosin 3	Homo sapiens	58-63
15911569-6	2005	N-terminal mutations of Trm1-II-GFP predicted to ablate N-acetylation cause nucleoplasmic location, whereas a variant with an N-terminal alteration predicted to allow N-acetylation by NatC is located at the INM, providing genetic support that Trm1p-II N-acetylation is necessary for its subnuclear INM location.	Nitrogen	0-1	tRNA (guanine26-N2)-dimethyltransferase	Saccharomyces cerevisiae S288C	24-28
16034098-5	2005	administration of nitrogen-containing bisphosphonate or pyrophosphomonoester drugs into cynomolgus monkeys combined with s.c. low-dose (6 x 10(5) U/animal) IL-2 induces a large pool of CD27+ and CD27- effector/memory T cells in the peripheral blood of treated animals.	Nitrogen	18-26	interleukin-2	Macaca fascicularis	156-160
21522749-3	2010	Furthermore, the conformation of the N-H bond is syn to the ortho-chloro group in the adjacent benzene ring.	Nitrogen	37-38	synemin	Homo sapiens	49-52
20463654-6	2010	Infusion of CD4+CD25+Treg cells into wild-type Balb/c mice reduced serum blood urea nitrogen and creatinine levels equivalent to those in nu/nu mice and extended their survival time after cisplatin injection.	Nitrogen	84-92	CD4 antigen	Mus musculus	12-15
20204527-7	2010	The synthesis of beta-galactosidase from the PDI2-lacZ fusion gene was markedly enhanced in the Pap1-positive KP1 cells by SNP and nitrogen starvation.	Nitrogen	131-139	peptidyl arginine deiminase 2	Homo sapiens	45-49
20204527-8	2010	However, the enhancement in the synthesis of beta-galactosidase from the PDI2-lacZ fusion gene by SNP and nitrogen starvation appeared to be relatively reduced in the Pap1-negative TP108-3C cells than in the Pap1-positive KP1 cells.	Nitrogen	106-114	peptidyl arginine deiminase 2	Homo sapiens	73-77
20204527-9	2010	The PDI2 mRNA level was elevated by SNP and nitrogen starvation in the Pap1-positive cells but not in the Pap1-negative cells.	Nitrogen	44-52	peptidyl arginine deiminase 2	Homo sapiens	4-8
20204527-10	2010	In brief, the S. pombe PDI2 plays a protective role against nitrosative and nutritional stresses, and is positively regulated by NO and nitrogen starvation in a Pap1-dependent manner.	Nitrogen	136-144	peptidyl arginine deiminase 2	Homo sapiens	23-27
20947728-1	2010	The exceptional spin coherence of nitrogen-vacancy centers in diamond motivates their function in emerging quantum technologies.	Nitrogen	34-42	spindlin 1	Homo sapiens	16-20
20964367-5	2010	NCl3 is hydrolyzed to yield NH2Cl and NHCl2, with subsequent decay to stable end products, including N2 and NO3-.	Nitrogen	101-103	calpain 5	Homo sapiens	0-4
20964367-7	2010	The pattern of nitrate yield is believed to be attributable to the fact that when urea serves as the source of reduced-N, entry into the reactions that describe chlorination of ammoniacal nitrogen is through NCl3, whereas when NH3 is the source of reduced-N, entry to these reactions is through NH2Cl.	Nitrogen	188-196	calpain 5	Homo sapiens	208-212
20533067-5	2010	Compared with other BPs, zoledronic acid (ZOL) has a higher affinity to bone mineral and is a stronger inhibitor of the enzyme farnesyl pyrophosphate synthase (the main target of nitrogen-containing BPs), properties that explain the prolonged effect of ZOL on bone turnover and render it a therapeutic option for JPD, similar to PDB.	Nitrogen	179-187	farnesyl diphosphate synthase	Homo sapiens	127-158
20693288-0	2010	N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway.	Nitrogen	0-1	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	21-27
20693288-3	2010	In this study, we show that promoters of the first N-glycosylation gene, DPAGT1, from Chinese hamster ovary (CHO), Madin-Darby canine kidney (MDCK), and human epidermoid carcinoma (A253) cells contain the T-cell factor/lymphoid enhancer-binding factor (TCF/LEF) consensus sequence.	Nitrogen	51-52	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	Cricetulus griseus	73-79
20693288-9	2010	Furthermore, up-regulation of DPAGT1 transcripts by Wnt3a led to altered N-glycosylation of E-cadherin.	Nitrogen	73-74	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	30-36
20693288-11	2010	Our results provide the first evidence that the Wnt/beta-catenin signaling pathway regulates the metabolic pathway of protein N-glycosylation by targeting DPAGT1 expression.	Nitrogen	126-127	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	155-161
20962926-0	2010	A decreased n-6/n-3 ratio in the fat-1 mouse is associated with improved glucose tolerance.	Nitrogen	12-13	FAT atypical cadherin 1	Mus musculus	33-38
20601226-10	2010	The 3D model of the catalytic domain of rat DPP III showed that the carboxyl oxygen atoms of Glu507 and Glu512 form the hydrogen bonds to the nitrogen atoms of His455 and His450.	Nitrogen	142-150	dipeptidylpeptidase 3	Rattus norvegicus	44-51
15949974-0	2005	Contribution of the Saccharomyces cerevisiae transcriptional regulator Leu3p to physiology and gene expression in nitrogen- and carbon-limited chemostat cultures.	Nitrogen	114-122	leucine-responsive transcriptional regulator LEU3	Saccharomyces cerevisiae S288C	71-76
15949974-2	2005	Leu3p is a pathway-specific regulator, known to regulate six genes involved in branched-chain amino-acid metabolism and one gene in nitrogen assimilation.	Nitrogen	132-140	leucine-responsive transcriptional regulator LEU3	Saccharomyces cerevisiae S288C	0-5
15863501-3	2005	In several if not all cell types, the N- and C-terminal domains of sPLA(2)-III were proteolytically removed, leading to the production of the form containing only the sPLA(2) domain, which could be further N-glycosylated at two consensus sites.	Nitrogen	38-39	phospholipase A2 group III	Homo sapiens	67-78
15863501-9	2005	Taken together, these results reveal unique cell type-specific processing and N-glycosylation of sPLA(2)-III and the potential role of this enzyme in cancer development by stimulating tumor cell growth and angiogenesis.	Nitrogen	78-79	phospholipase A2 group III	Homo sapiens	97-108
21561822-5	2011	Two human LPL N-glycosylation sites were conserved among seven predicted sites for the vertebrate LPL sequences examined.	Nitrogen	14-15	lipoprotein lipase	Homo sapiens	98-101
21410905-0	2011	N-glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role.	Nitrogen	0-1	melanocortin 1 receptor	Homo sapiens	29-52
15747319-3	2005	However, in the case of Z-Gly-2Pyg-Gly-OMe, the intramolecular hydrogen bonding between 2Pyg-NH and the pyridine nitrogen was not observed, whereas Z-Aib-2Pyg-Aib-OMe adopts a unique conformation with an intramolecular hydrogen bond between 2Pyg-NH and a pyridine nitrogen.	Nitrogen	113-121	ANIB1	Homo sapiens	150-153
15747319-3	2005	However, in the case of Z-Gly-2Pyg-Gly-OMe, the intramolecular hydrogen bonding between 2Pyg-NH and the pyridine nitrogen was not observed, whereas Z-Aib-2Pyg-Aib-OMe adopts a unique conformation with an intramolecular hydrogen bond between 2Pyg-NH and a pyridine nitrogen.	Nitrogen	264-272	ANIB1	Homo sapiens	150-153
15747319-3	2005	However, in the case of Z-Gly-2Pyg-Gly-OMe, the intramolecular hydrogen bonding between 2Pyg-NH and the pyridine nitrogen was not observed, whereas Z-Aib-2Pyg-Aib-OMe adopts a unique conformation with an intramolecular hydrogen bond between 2Pyg-NH and a pyridine nitrogen.	Nitrogen	264-272	ANIB1	Homo sapiens	159-162
20691677-9	2010	The Pulse Tube cryorefrigerator may represent a valid alternative solution to programmable liquid nitrogen freezer, especially where nitrogen"s supply is difficult or extremely expensive.	Nitrogen	133-141	tubulin epsilon 1	Homo sapiens	10-14
20927321-5	2010	Our studies have shown that the n-3 PUFA species, docosahexaenoic acid (DHA), increases SDC-1 expression in prostate tissues of Pten knockout (Pten(P-/-)) mice/cells and human prostate cancer cells.	Nitrogen	21-22	pumilio RNA binding family member 3	Homo sapiens	36-40
20927321-10	2010	A diet enriched in n-3 PUFA decreased phosphorylation of PDK1, Akt (T308), and Bad in prostates of Pten(P-/-) mice.	Nitrogen	8-9	pumilio RNA binding family member 3	Homo sapiens	23-27
21410905-2	2011	MC1R has two putative N-glycosylation targets, Asn15 and Asn29.	Nitrogen	22-23	melanocortin 1 receptor	Homo sapiens	0-4
21410905-5	2011	We demonstrate that MC1R is N-glycosylated at Asn15 and Asn29, with structurally and functionally different glycan chains.	Nitrogen	28-29	melanocortin 1 receptor	Homo sapiens	20-24
15924140-2	2005	We identified three children with mendelian susceptibility to mycobacterial disease who were homozygous with respect to a missense mutation in IFNGR2 creating a new N-glycosylation site in the IFNgammaR2 chain.	Nitrogen	145-146	interferon gamma receptor 2	Homo sapiens	193-203
21410905-6	2011	N-glycosylation is not necessary for high affinity agonist binding or functional coupling but has a strong effect on the availability of MC1R molecules on the plasma membrane, most likely by a combination of improved forward trafficking and decreased internalization.	Nitrogen	0-1	melanocortin 1 receptor	Homo sapiens	137-141
21328905-3	2010	Methods for the use of radon- and nitrogen-containing thermal waters from their natural sources of the Altai region for the purpose of sanatorium and spa treatment are described.	Nitrogen	34-42	surfactant protein A2	Homo sapiens	150-153
21515696-0	2011	ABI4 activates DGAT1 expression in Arabidopsis seedlings during nitrogen deficiency.	Nitrogen	64-72	membrane bound O-acyl transferase (MBOAT) family protein	Arabidopsis thaliana	15-20
21515696-8	2011	Taken together, our results indicate that abscisic acid signaling is part of the regulatory machinery governing TAG ectopic accumulation and that ABI4 is essential for the activation of DGAT1 in Arabidopsis seedlings during nitrogen deficiency.	Nitrogen	224-232	membrane bound O-acyl transferase (MBOAT) family protein	Arabidopsis thaliana	186-191
20632335-2	2010	Subjection of the syn diastereomers to NAC-gold catalysts (NAC=nitrogen acyclic carbene) in the presence of external nucleophiles such as water or anilines provided substituted and highly rigid heterocyclic cages.	Nitrogen	63-71	synemin	Homo sapiens	18-21
15941833-8	2005	Rapid and transient activation of endothelial NAD(P)H oxidases was responsible for the initial burst production of O2* (Rac1 inhibitor NSC 23766 but not an N-nitro-L-arginine-methyl ester-attenuated ESR O2*- signal at 30 min) in response to angiotensin II, preceding a second peak in O2*- production at 24 h that predominantly depended on uncoupled eNOS.	Nitrogen	46-47	Rac family small GTPase 1	Homo sapiens	120-124
21573946-0	2011	N-Glycosylation profiling of recombinant mouse extracellular superoxide dismutase produced in Chinese hamster ovary cells.	Nitrogen	0-1	superoxide dismutase 3, extracellular	Mus musculus	47-81
15916748-1	2005	It has already been reported that stably expressed exogenous human wild-type EPO (wtEPO) is preferentially secreted to the apical side and one of the three N-linked carbohydrate chains critically acts as an apical sorting determinant in Madin-Darby canine kidney (MDCK) cells.	Nitrogen	156-157	erythropoietin	Canis lupus familiaris	77-80
20729985-0	2010	N-Alkyl-octahydroisoquinolin-1-one-8-carboxamides: a Novel Class of Selective, Nonbasic, Nitrogen-Containing kappa-Opioid Receptor Ligands.	Nitrogen	89-97	opioid receptor kappa 1	Homo sapiens	109-130
21378189-6	2011	The results revealed that utilization of L-Ala, L-Trp, D-Ala, and a specific set of D-amino acids as sole nitrogen sources was abolished in the dadA mutant and/or severely hampered in the dadR mutant while growth yield on D-amino acids was surprisingly improved in the dadX mutant.	Nitrogen	106-114	D-amino acid dehydrogenase small subunit	Pseudomonas aeruginosa PAO1	144-148
20544107-2	2010	We synthesized and studied a new type of nitrogen-containing bisphosphonate analogs and developed a sensitive end point assay method for enzyme FPPS, which was used for inhibitor screening.	Nitrogen	41-49	farnesyl diphosphate synthase	Homo sapiens	144-148
20670019-1	2010	The Suzuki reactions of diboronic acid 1 and bromo-spirooxazine 2, under N(2) atmosphere and aerobic conditions, gave the dispirooxazine-substituted binaphthyl product 3 and the monospirooxazine-substituted binaphthyl derivative 4, respectively.	Nitrogen	73-77	mediator complex subunit 25	Homo sapiens	34-40
20491941-0	2010	The Fps1p aquaglyceroporin facilitates the use of small aliphatic amides as a nitrogen source by amidase-expressing yeasts.	Nitrogen	78-86	Fps1p	Saccharomyces cerevisiae S288C	4-9
20491941-3	2010	However, in Z. rouxii, the loss of Fps1p severely compromised the use of acetamide and several other small amides as sources of nitrogen, an indication that these amides enter the cells of this yeast by passive diffusion through the Fps1p pore.	Nitrogen	128-136	Fps1p	Saccharomyces cerevisiae S288C	35-40
15941397-0	2005	Identification and expression analysis of two inorganic C- and N-responsive genes encoding novel and distinct molecular forms of eukaryotic phosphoenolpyruvate carboxylase in the green microalga Chlamydomonas reinhardtii.	Nitrogen	63-64	uncharacterized protein	Chlamydomonas reinhardtii	140-171
15833284-5	2005	The heavy chains yielded post-translational modifications previously reported for other recombinant humanized or human IgG1 such as N-terminal pyroglutamic acid, C-terminal lysine clipping and N-glycosylation for asparagine 297.	Nitrogen	132-133	LOC105243590	Mus musculus	119-123
15857138-9	2005	Additionally, the n-pentadecanoyl derivative had a residual effect on tyrosinase activity that existed for at least 4 days after the peptide was removed from the human melanocyte culture medium.	Nitrogen	7-8	tyrosinase	Homo sapiens	70-80
15860005-3	2005	Consistent with the known function of the OST complex in eukaryotes, the dgl1-1 mutation led to a reduced N-linked glycosylation of the ER-resident protein disulfide isomerase.	Nitrogen	106-107	dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein	Arabidopsis thaliana	73-79
15860005-8	2005	Together, these results confirm the role of DGL1 in N-linked glycosylation, cell growth and differentiation in plants.	Nitrogen	52-53	dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein	Arabidopsis thaliana	44-48
21332510-2	2011	As GMPase is important for GDP-mannose biosynthesis, a nucleotide sugar necessary for protein N-glycosylation, it has been thought that GDP-mannose deficiency is responsible for the growth defect in vtc1-1 in the presence of NH(4) (+) .	Nitrogen	94-95	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	199-205
15737642-0	2005	The effects of N-glycosylation sites and the N-terminal region on the biological function of beta1,3-N-acetylglucosaminyltransferase 2 and its secretion.	Nitrogen	15-16	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	93-134
15737642-2	2005	To obtain insight into the structure of beta3GnT2, the effects of N-glycosylation on its biological function were evaluated using the addition of inhibitors, site-directed mutagenesis of potential N-glycosylation sites, and deletion of its N-terminal region using a fusion protein with GFP(uv) in a baculovirus expression system.	Nitrogen	66-67	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	40-49
15737642-4	2005	The N-glycosylation at Asn219 was necessary for the beta3GnT activity; moreover, N-glycosylation at Asn127 and Asn219 was critical for efficient protein secretion.	Nitrogen	4-5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	52-60
20582921-0	2010	Syntheses and activities of backbone-side chain cyclic octapeptide ligands with N-functionalized phosphotyrosine for the N-terminal SH2-domain of the protein tyrosine phosphatase SHP-1.	Nitrogen	80-81	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	179-184
20622883-0	2010	N-linked glycosylation selectively regulates autonomous precursor BCR function.	Nitrogen	0-1	BCR activator of RhoGEF and GTPase	Homo sapiens	66-69
20622883-5	2010	A conserved asparagine (N)-linked glycosylation site at position 46 (N46) in the first conserved domain of muHC was absolutely required for pre-BCR function, and swapping that domain with deltaHC resulted in a functional deltaHC-containing pre-BCR.	Nitrogen	23-26	BCR activator of RhoGEF and GTPase	Homo sapiens	144-147
20622883-5	2010	A conserved asparagine (N)-linked glycosylation site at position 46 (N46) in the first conserved domain of muHC was absolutely required for pre-BCR function, and swapping that domain with deltaHC resulted in a functional deltaHC-containing pre-BCR.	Nitrogen	23-26	BCR activator of RhoGEF and GTPase	Homo sapiens	244-247
21332510-5	2011	Using qRT-PCR and staining procedures, we demonstrate that defective N-glycosylation in vtc1-1 contributes to cell wall, membrane and cell cycle defects, resulting in root growth inhibition in the presence of NH(4) (+) .	Nitrogen	69-70	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	88-94
21248038-1	2011	The broadly neutralizing human monoclonal antibody 2G12 binds to a carbohydrate-dependent epitope involving three major potential N-linked glycosylation sites (PNGS) of gp120 (N295, N332, and N392).	Nitrogen	130-131	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	169-174
20583790-4	2010	The peptide nitrogen of conserved residues PsaA-Leu722 and PsaB-Leu706 is involved in asymmetric hydrogen-bonding to PhQ(A) and PhQ(B), respectively.	Nitrogen	12-20	photosystem I P700 chlorophyll a apoprotein A2	Chlamydomonas reinhardtii	59-63
21173144-7	2011	Both TPC1 and TPC2 are N-glycosylated with residues 599, 611, and 616 contributing to glycosylation of TPC1.	Nitrogen	23-24	two pore segment channel 2	Homo sapiens	14-18
20450493-2	2010	FDPS is also the molecular target of nitrogen-containing bisphosphonates, which are used as bone-antiresorptive drugs in various disorders.	Nitrogen	37-45	farnesyl diphosphate synthase	Homo sapiens	0-4
21314128-4	2011	Variation of the 2-N-benzyl and 3-alkoxy substituents resulted in the identification of 3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)-2-(4-nitrobenzyl)isoindolin-1-one (74) as a potent MDM2-p53 inhibitor (IC(50) = 0.23 +- 0.01 muM).	Nitrogen	18-20	transformed mouse 3T3 cell double minute 2	Mus musculus	200-204
20504872-8	2010	Lectin binding studies revealed the presence of both N- and O-linked glycosylation in baculovirus-expressed ZP1.	Nitrogen	53-54	zona pellucida glycoprotein 1	Homo sapiens	108-111
20304457-2	2010	Env"s extensive and heterogeneous N-linked glycosylation affects folding, binding to lectin receptors, antigenicity and immunogenicity.	Nitrogen	34-35	endogenous retrovirus group K member 20	Homo sapiens	0-3
20304457-7	2010	Manipulating Env"s N-glycosylation may be useful for structural and functional studies and for vaccine design.	Nitrogen	19-20	endogenous retrovirus group K member 20	Homo sapiens	13-16
21314128-4	2011	Variation of the 2-N-benzyl and 3-alkoxy substituents resulted in the identification of 3-(4-chlorophenyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)-2-(4-nitrobenzyl)isoindolin-1-one (74) as a potent MDM2-p53 inhibitor (IC(50) = 0.23 +- 0.01 muM).	Nitrogen	18-20	transformation related protein 53, pseudogene	Mus musculus	205-208
20228058-10	2010	In total, this study provides the first profile of differential protein abundance during pseudohyphal growth, identifying a previously uncharacterized membrane compartment of Can1 protein required for wild-type nitrogen signaling and filamentous growth.	Nitrogen	211-219	arginine permease CAN1	Saccharomyces cerevisiae S288C	175-179
21051484-0	2011	Hap2-3-5-Gln3 determine transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions in the yeast Saccharomyces cerevisiae.	Nitrogen	85-93	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	9-13
20164234-4	2010	Our results showed that two potential N-linked glycosylation (PNLG) sites in the V2 and C2 regions of Env gp120 played an important role in regulating the susceptibility of CRF01_AE Env to b12.	Nitrogen	38-39	endogenous retrovirus group K member 20	Homo sapiens	102-105
20164234-4	2010	Our results showed that two potential N-linked glycosylation (PNLG) sites in the V2 and C2 regions of Env gp120 played an important role in regulating the susceptibility of CRF01_AE Env to b12.	Nitrogen	38-39	endogenous retrovirus group K member 20	Homo sapiens	182-185
20237017-6	2010	We further demonstrate that ZmYUC catalyzes the N-hydroxylation of tryptamine and that sugar levels regulate transcript levels of ZmYUC, both in in vitro-cultured kernels and in a promoter-reporter fusion in Arabidopsis.	Nitrogen	48-49	flavin monooxygenase	Zea mays	28-33
19446658-8	2010	In nSP we found that the number of potential N-linked glycosylation sites (PNGS) increased over time, whereas no pattern of change was observed in SP.	Nitrogen	45-46	sperm antigen with calponin homology and coiled-coil domains 1	Homo sapiens	3-6
21051484-0	2011	Hap2-3-5-Gln3 determine transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions in the yeast Saccharomyces cerevisiae.	Nitrogen	85-93	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	54-58
21051484-3	2011	The results presented in this paper show that transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions is achieved through the action of the novel Hap2-3-5-Gln3 transcriptional regulator.	Nitrogen	107-115	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	76-80
21051484-3	2011	The results presented in this paper show that transcriptional activation of GDH1 and ASN1 under repressive nitrogen conditions is achieved through the action of the novel Hap2-3-5-Gln3 transcriptional regulator.	Nitrogen	107-115	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	180-184
21675219-7	2011	Total N and Organic matter content in Yellow Sea of South Korea were relatively high.	Nitrogen	6-7	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	45-48
20386969-0	2010	Purification and N-glycosylation analysis of melanoma antigen dopachrome tautomerase.	Nitrogen	17-18	dopachrome tautomerase	Homo sapiens	62-84
20386969-7	2010	Analysis of DCT tryptic peptides by MALDI-TOF/TOF determined N-glycosylation as a primary post-translational modification.	Nitrogen	61-62	dopachrome tautomerase	Homo sapiens	12-15
20386969-8	2010	Our success in the expression of soluble mammalian DCT and the characterization of N-glycosylation sites is a useful reference toward the comprehensive understanding of the structure/function relationship of mammalian DCT.	Nitrogen	83-84	dopachrome tautomerase	Homo sapiens	218-221
21455488-4	2011	Previously, we reported that the NITROGEN LIMITATION ADAPTATION (NLA) gene is involved in adaptive responses to low-nitrogen conditions in Arabidopsis, where nla mutant plants display abrupt early senescence.	Nitrogen	116-124	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	33-63
20141178-0	2010	Five-membered arsenic-sulfur-nitrogen heterocycles, RAs(S2N2) (R = Me, Et, (i)Pr, (t)Bu, Ph, Mes).	Nitrogen	29-37	MKS transition zone complex subunit 1	Homo sapiens	93-96
19880378-4	2010	In these models, POMT1 and POMT2 have seven- and nine-transmembrane helices and contain four and five potential N-glycosylation sites, respectively.	Nitrogen	112-113	protein O-mannosyltransferase 1	Homo sapiens	17-22
19880378-4	2010	In these models, POMT1 and POMT2 have seven- and nine-transmembrane helices and contain four and five potential N-glycosylation sites, respectively.	Nitrogen	112-113	protein O-mannosyltransferase 2	Homo sapiens	27-32
19880378-6	2010	Three of the POMT1 sites and all of the POMT2 sites were found to be N-glycosylated, suggesting that these sites face the luminal side of the endoplasmic reticulum.	Nitrogen	69-70	protein O-mannosyltransferase 1	Homo sapiens	13-18
19880378-6	2010	Three of the POMT1 sites and all of the POMT2 sites were found to be N-glycosylated, suggesting that these sites face the luminal side of the endoplasmic reticulum.	Nitrogen	69-70	protein O-mannosyltransferase 2	Homo sapiens	40-45
19880378-7	2010	Mutation of any single site did not significantly affect POMT activity, but mutations of all N-glycosylation sites of either POMT1 or POMT2 caused a loss of POMT activity.	Nitrogen	93-94	protein O-mannosyltransferase 1	Homo sapiens	125-130
21455488-4	2011	Previously, we reported that the NITROGEN LIMITATION ADAPTATION (NLA) gene is involved in adaptive responses to low-nitrogen conditions in Arabidopsis, where nla mutant plants display abrupt early senescence.	Nitrogen	116-124	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	65-68
19880378-7	2010	Mutation of any single site did not significantly affect POMT activity, but mutations of all N-glycosylation sites of either POMT1 or POMT2 caused a loss of POMT activity.	Nitrogen	93-94	protein O-mannosyltransferase 2	Homo sapiens	134-139
19880378-9	2010	These results suggest that the N-glycosylation of POMT1 and POMT2 is required for maintaining the conformation as well as the activity of the POMT1-POMT2 complex.	Nitrogen	31-32	protein O-mannosyltransferase 1	Homo sapiens	50-55
21455488-4	2011	Previously, we reported that the NITROGEN LIMITATION ADAPTATION (NLA) gene is involved in adaptive responses to low-nitrogen conditions in Arabidopsis, where nla mutant plants display abrupt early senescence.	Nitrogen	116-124	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	158-161
19880378-9	2010	These results suggest that the N-glycosylation of POMT1 and POMT2 is required for maintaining the conformation as well as the activity of the POMT1-POMT2 complex.	Nitrogen	31-32	protein O-mannosyltransferase 2	Homo sapiens	60-65
21070866-1	2011	BACKGROUND: Dietary n-3 polyunsaturated fatty acid (PUFA) deprivation increases expression of arachidonic acid (AA 20:4n-6)-selective cytosolic phospholipase A(2) (cPLA(2)) IVA and cyclooxygenase (COX)-2 in rat brain, while decreasing expression of docosahexaenoic acid (DHA 22:6n-3)-selective calcium-independent iPLA(2) VIA.	Nitrogen	20-21	phospholipase A2 group IVA	Rattus norvegicus	134-171
19880378-9	2010	These results suggest that the N-glycosylation of POMT1 and POMT2 is required for maintaining the conformation as well as the activity of the POMT1-POMT2 complex.	Nitrogen	31-32	protein O-mannosyltransferase 1	Homo sapiens	142-147
19880378-9	2010	These results suggest that the N-glycosylation of POMT1 and POMT2 is required for maintaining the conformation as well as the activity of the POMT1-POMT2 complex.	Nitrogen	31-32	protein O-mannosyltransferase 2	Homo sapiens	148-153
21374892-9	2011	In only spinal tissues, ERK 1/2 and CREB proteins in the NP+Lido group was significantly reduced to 39%, and 48% in comparison with the NP+NS group.	Nitrogen	139-141	cAMP responsive element binding protein 1	Rattus norvegicus	36-40
19898896-3	2010	Prestin was earlier identified to possess two N-glycosylation sites (N163, N166) that, when mutated, marginally affect prestin nonlinear capacitance (NLC) function in cultured cells.	Nitrogen	46-47	solute carrier family 26 member 5	Homo sapiens	0-7
20031186-4	2010	At the Ti/IrO(2) anode, a pH value of 12, the presence of chloride and a potential fixed around 2.3 V vs Hg/HgO permitted the production of hypochlorite, leading to the oxidation of ammonia to nitrogen with a N(2) selectivity of 100%.	Nitrogen	193-201	homogentisate 1,2-dioxygenase	Homo sapiens	108-111
20943674-2	2011	Here we determined the site-specific N-glycosylation profile of human lactoferrin (hLF) and recombinant human lactoferrin (rhLF) expressed in the milk of transgenic cloned cattle.	Nitrogen	37-38	HLF transcription factor, PAR bZIP family member	Homo sapiens	83-86
20031186-4	2010	At the Ti/IrO(2) anode, a pH value of 12, the presence of chloride and a potential fixed around 2.3 V vs Hg/HgO permitted the production of hypochlorite, leading to the oxidation of ammonia to nitrogen with a N(2) selectivity of 100%.	Nitrogen	209-210	homogentisate 1,2-dioxygenase	Homo sapiens	108-111
21579807-1	2010	In the title compound, C(8)H(5)Br(3)ClNO, the conformation of the N-H bond is syn to the 2-chloro substituent in the benzene ring.	Nitrogen	38-39	synemin	Homo sapiens	78-81
19938875-3	2010	Moreover, protonation of the PLP pyridine nitrogen further drives the equilibrium toward the oxoenamine direction.	Nitrogen	42-50	proteolipid protein 1	Homo sapiens	29-32
19938875-6	2010	Both Asp271 and Lys303 stabilize the hydroxyimine configuration through hydrogen-bonding interactions with the pyridine nitrogen of the PLP and the imino nitrogen of the Schiff base, respectively.	Nitrogen	120-128	proteolipid protein 1	Homo sapiens	136-139
20943674-11	2011	The different N-glycosylation profile of rhLF when compared with that of hLF is in consistent with the widely held view that glycosylation is species- and tissue/cell-specific.	Nitrogen	14-15	HLF transcription factor, PAR bZIP family member	Homo sapiens	42-45
19957936-6	2010	Rather than regeneration of initial complex 1 after the light-induced H(2)O(2) evolution in the catalytic cycle, the DFT calculations predict a new route with a lower energy barrier via the regeneration of 1", an isomer of 1 with the unsaturated carbon at the nitrogen side arm of the PNN ligand.	Nitrogen	260-268	pinin, desmosome associated protein	Homo sapiens	285-288
21131548-4	2011	To understand the effects of Mo deficiency and a mutation in a molybdate transporter, MOT1, on nitrogen and sulphur metabolism in Arabidopsis thaliana, transcript and metabolite profiling of the mutant lacking MOT1 was conducted in the presence or absence of Mo.	Nitrogen	95-103	molybdate transporter 1	Arabidopsis thaliana	86-90
19880754-8	2010	Sak1 was also required for increased Thr210 phosphorylation of Snf1 under nitrogen-limiting conditions.	Nitrogen	74-82	serine/threonine protein kinase SAK1	Saccharomyces cerevisiae S288C	0-4
19880754-10	2010	Thus, while the Snf1-activating kinases exhibit redundancy for growth on nonpreferred carbon sources, the loss of Sak1 alone produced a significant defect in a nitrogen-regulated phenotype, and this defect resulted from deficient Snf1 activation rather than from disruption of another pathway.	Nitrogen	160-168	serine/threonine protein kinase SAK1	Saccharomyces cerevisiae S288C	114-118
19880754-11	2010	Our results suggest that Sak1 is involved in nitrogen signaling upstream of Snf1.	Nitrogen	45-53	serine/threonine protein kinase SAK1	Saccharomyces cerevisiae S288C	25-29
21053013-7	2011	Among these phosphoproteins, phosphoenolpyruvate carboxylase and NADH: nitrate reductase (NR) which catalyzes the rate-limiting and regulated step in the pathway of inorganic nitrogen assimilation were identified.	Nitrogen	175-183	MLO-like protein 4	Zea mays	29-60
21053013-7	2011	Among these phosphoproteins, phosphoenolpyruvate carboxylase and NADH: nitrate reductase (NR) which catalyzes the rate-limiting and regulated step in the pathway of inorganic nitrogen assimilation were identified.	Nitrogen	175-183	nitrate reductase [NADH] 1	Zea mays	71-88
21383973-6	2011	Early-transmitting viruses in subtypes A and C mucosal transmission tend to encode gp120s with reduced numbers of N-linked glycosylation sites at specific positions throughout the V1-V4 domains, relative to typical chronically replicating isolates in the donor quasispecies.	Nitrogen	114-115	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	83-88
15592895-1	2005	The dengue 2 virus (DENV-2) NS1 glycoprotein contains two potential sites for N-linked glycosylation at Asn-130 and Asn-207.	Nitrogen	22-23	influenza virus NS1A binding protein	Homo sapiens	28-31
21383973-8	2011	Using primary alpha4beta7/CD4+ T cells and a flow-cytometry based steady-state binding assay we show that the removal of transmission-associated N-linked glycosylation sites results in large increases in the specific reactivity of gp120 for integrin-alpha4beta7.	Nitrogen	145-146	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	231-236
21142036-2	2011	Previously, we utilized N-linked glycosylation reporter tags along with membrane insertion and topology assays to define the 11 membrane-spanning domains (I-XI) of PC1.	Nitrogen	24-25	polycystin 1, transient receptor potential channel interacting	Homo sapiens	164-167
15518587-1	2005	We have shown that SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) proteins not only participate directly in exocytosis, but also regulate the dominant membrane-repolarizing Kv channels (voltage-gated K+ channels), such as Kv2.1, in pancreatic beta-cells.	Nitrogen	20-21	potassium voltage-gated channel subfamily B member 1	Homo sapiens	261-266
21142131-1	2011	The neutral molecule temperature dependence of the rate coefficient for the electron transfer reaction from H(2)O to N(2)(+) is determined using a coaxial molecular beam radio frequency ring electrode ion trap (CoMB-RET) method.	Nitrogen	117-118	ret proto-oncogene	Homo sapiens	216-219
21149418-3	2011	However, unlike these other family representatives, which are typically transmembrane receptors with extracellular ligand-binding domains, FCRLA has no predicted transmembrane domain or N-linked glycosylation sites and is an intracellular protein.	Nitrogen	186-187	Fc receptor like A	Homo sapiens	139-144
15671042-8	2005	Cellular localization and glycosylation studies revealed the hFKBP65 protein to be localized in the endoplasmic reticulum, and to be N-glycosylated.	Nitrogen	133-134	FKBP prolyl isomerase 10	Homo sapiens	61-68
15670755-0	2005	Nitrogen-containing bisphosphonate, YM529/ONO-5920 (a novel minodronic acid), inhibits RANKL expression in a cultured bone marrow stromal cell line ST2.	Nitrogen	0-8	TNF superfamily member 11	Homo sapiens	87-92
22324412-10	2011	In G. carnosum, corn stem/NH4NO3 medium with nitrogen concentration of 20 mM was the optimum for Mn-dependent peroxidase production (88.00 U L-1), while the highest versatile peroxidase activity was detected in the medium with grapevine sawdust and 10 mM of nitrogen (80.80 U L-1).	Nitrogen	45-53	L1 cell adhesion molecule	Mus musculus	141-144
15670755-0	2005	Nitrogen-containing bisphosphonate, YM529/ONO-5920 (a novel minodronic acid), inhibits RANKL expression in a cultured bone marrow stromal cell line ST2.	Nitrogen	0-8	ST2	Homo sapiens	148-151
15674979-6	2005	Bulkier N-Alk (Alk&gt;Me) substrates 5 did not react due to the hindered approach to the encapsulated NO+ reagents.	Nitrogen	8-9	ALK receptor tyrosine kinase	Homo sapiens	10-13
21058296-1	2011	Based on the crystal structure of the extracellular domain (ECD) of the mouse nicotinic acetylcholine receptor (nAChR) alpha1 subunit bound to alpha-bungarotoxin (alpha-Btx) we have generated in silico models of the human nAChR alpha1 bound to alpha-Btx and alpha-cobratoxin (alpha-Cbtx), both in the presence and in the absence of the N-linked carbohydrate chain.	Nitrogen	336-337	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	78-110
15674979-6	2005	Bulkier N-Alk (Alk&gt;Me) substrates 5 did not react due to the hindered approach to the encapsulated NO+ reagents.	Nitrogen	8-9	ALK receptor tyrosine kinase	Homo sapiens	15-18
15537792-3	2005	The XEEL protein is a homohexamer of 43-kDa N-glycosylated peptide subunits linked by disulfide bonds.	Nitrogen	44-45	intelectin 1 L homeolog	Xenopus laevis	4-8
15507441-6	2005	However, in the third glycosylated subunit, Stt3p, there are two adjacent potential N-glycosylation sites (N(535)NTWN(539)NT) that, in contrast to the other subunits, are highly conserved in eukaryotic organisms.	Nitrogen	84-85	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	44-49
21058296-1	2011	Based on the crystal structure of the extracellular domain (ECD) of the mouse nicotinic acetylcholine receptor (nAChR) alpha1 subunit bound to alpha-bungarotoxin (alpha-Btx) we have generated in silico models of the human nAChR alpha1 bound to alpha-Btx and alpha-cobratoxin (alpha-Cbtx), both in the presence and in the absence of the N-linked carbohydrate chain.	Nitrogen	336-337	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	112-117
15507441-7	2005	Mass spectrometric analysis of a tryptic digest of Stt3p showed that the peptide containing the two adjacent N-glycosylation sites was N-glycosylated at one site.	Nitrogen	109-110	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	51-56
15507441-7	2005	Mass spectrometric analysis of a tryptic digest of Stt3p showed that the peptide containing the two adjacent N-glycosylation sites was N-glycosylated at one site.	Nitrogen	135-136	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	51-56
15507441-12	2005	Based on these studies, we conclude that N-glycosylation of Stt3p at Asn(539) is essential for its function in the OT complex.	Nitrogen	41-42	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	60-65
15630029-10	2005	Intermediate-chain n-3 PUFAs were particularly associated with CHD risk when long-chain n-3 PUFA intake was very low (&lt;100 mg/d); among these men, each 1 g/d of intermediate-chain n-3 PUFA intake was associated with an approximately 50% lower risk of nonfatal MI (HR=0.42; 95% CI=0.23 to 0.75) and total CHD (HR=0.53; 95% CI=0.34 to 0.83).	Nitrogen	1-2	pumilio RNA binding family member 3	Homo sapiens	23-27
20578979-7	2010	Analyses of structure-function relationships revealed that the substituent at the nitrogen atom in the isoindole ring is of crucial impact for the activity of CYP2C9/19.	Nitrogen	82-90	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	159-165
17282906-1	2005	Rapid, non-destructive estimation of nitrogen content of crop is a potentially important application for both farm managers and researchers.	Nitrogen	37-45	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	57-61
17282906-2	2005	This paper presents the development of a multi-spectral nitrogen deficiency sensor, which uses three channels (green, red, near-infrared) of crop images to estimate nitrogen level of the canola.	Nitrogen	56-64	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	141-145
17282906-2	2005	This paper presents the development of a multi-spectral nitrogen deficiency sensor, which uses three channels (green, red, near-infrared) of crop images to estimate nitrogen level of the canola.	Nitrogen	165-173	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	141-145
20444205-1	2010	Nitrogen (N) metabolism was characterized in the developing ear of glutamine synthetase deficient mutants (gln1-3, gln1-4 and gln1-3/gln1-4) of maize exhibiting a reduction in kernel yield.	Nitrogen	0-8	glutamine synthetase, chloroplastic	Zea mays	115-121
15723621-1	2005	Arylamine N-acetyltransferases (NAT) are xenobiotic-metabolizing enzymes responsible for N-acetylation of many arylamines.	Nitrogen	10-11	bromodomain containing 2	Homo sapiens	32-35
20444205-1	2010	Nitrogen (N) metabolism was characterized in the developing ear of glutamine synthetase deficient mutants (gln1-3, gln1-4 and gln1-3/gln1-4) of maize exhibiting a reduction in kernel yield.	Nitrogen	0-8	glutamine synthetase, chloroplastic	Zea mays	133-139
15475412-11	2005	In contrast, the K(m) value of AFQ N-glucuronidation in recombinant UGT1A3 microsomes was relatively close to that in human jejunum microsomes.	Nitrogen	35-36	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	68-74
15475412-12	2005	These results demonstrate that AFQ N-glucuronidation in human is mainly catalyzed by UGT1A4 in the liver and by UGT1A3, as well as UGT1A4 in the intestine.	Nitrogen	35-36	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	112-118
20444205-3	2010	The ear of gln1-3 and gln1-3/gln1-4 had a higher free amino acid content and a lower C/N ratio, when compared to the wild type.	Nitrogen	87-88	glutamine synthetase, chloroplastic	Zea mays	29-35
20713656-5	2010	Consistent with these observations, the UGT1A4 inhibitor hecogenin and the UGT2B7 substrate diclofenac potently inhibited the N- and O-glucuronidation of 1"-hydroxymidazolam in HLMs, respectively.	Nitrogen	126-127	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	40-46
15486227-9	2005	To elucidate the physiological functions of STC2, recombinant human and fish STC2 proteins were generated and found to be N-glycosylated homodimers.	Nitrogen	122-123	stanniocalcin 2	Homo sapiens	44-48
15486227-9	2005	To elucidate the physiological functions of STC2, recombinant human and fish STC2 proteins were generated and found to be N-glycosylated homodimers.	Nitrogen	122-123	stanniocalcin 2	Homo sapiens	77-81
20399272-9	2010	In particular, an 88 amino acid tryptic peptide covering the presumed substrate binding domains HP1, TMD7, HP2, and TMD8 domains of EAAT2 was also identified after N-deglycosylation.	Nitrogen	164-165	chromobox 5	Homo sapiens	96-99
16311805-3	2005	To increase diversity, nitrogen group of Boc-sulfamides was alkylated with alcohols using Mitsunobu reaction and Boc-group was removed using Si-TsOH.	Nitrogen	23-31	BOC cell adhesion associated, oncogene regulated	Homo sapiens	41-44
16311805-3	2005	To increase diversity, nitrogen group of Boc-sulfamides was alkylated with alcohols using Mitsunobu reaction and Boc-group was removed using Si-TsOH.	Nitrogen	23-31	BOC cell adhesion associated, oncogene regulated	Homo sapiens	113-116
20950000-1	2010	A computational study of hydrogen-bonded complexes of F(3)CH and C1H and of lithium-bonded complexes of F(3)CLi and CILi, with small molecules such as N(2) and H(2)O was undertaken at the MP2/6-311++G(d,p) level of theory.	Nitrogen	151-155	tryptase pseudogene 1	Homo sapiens	188-191
15583810-3	2005	In the present study, by Western blotting, we analyzed the N-glycosylation patterns in CD45 having L-PHA reactive oligosaccharides.	Nitrogen	59-60	protein tyrosine phosphatase receptor type C	Homo sapiens	87-91
15583810-6	2005	Therefore, the differences in CD45 molecular weight between the two cases is due to differences in the amount of N-glycosylation.	Nitrogen	113-114	protein tyrosine phosphatase receptor type C	Homo sapiens	30-34
15583810-13	2005	Alteration in N-glycosylation of CD45 may regulate lymphoma cell growth in DLBCL through the interaction between the N-glycans of CD45 and galectin-1.	Nitrogen	14-15	protein tyrosine phosphatase receptor type C	Homo sapiens	33-37
15583810-13	2005	Alteration in N-glycosylation of CD45 may regulate lymphoma cell growth in DLBCL through the interaction between the N-glycans of CD45 and galectin-1.	Nitrogen	14-15	protein tyrosine phosphatase receptor type C	Homo sapiens	130-134
20643191-1	2010	We investigated the functional relationship between the soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) protein syntaxin 1A (syn 1A) and the dopamine transporter (DAT) by treating rat striatal tissue with Botulinum Neurotoxin C (BoNT/C) and co-transfecting syn 1A with DAT in non-neuronal cells, followed by analysis of DAT activity, phosphorylation, and regulation.	Nitrogen	64-65	syntaxin 1A	Rattus norvegicus	134-145
15522226-0	2004	Endoplasmic reticulum stress and N-glycosylation modulate expression of WFS1 protein.	Nitrogen	33-34	wolframin ER transmembrane glycoprotein	Mus musculus	72-76
15522226-4	2004	Another ER-stress inducer, the N-glycosylation inhibitor tunicamycin, also raised WFS1 mRNA but not protein levels.	Nitrogen	31-32	wolframin ER transmembrane glycoprotein	Mus musculus	82-86
15522226-5	2004	Site-directed mutagenesis showed both Asn-663 and Asn-748 to be N-glycosylated in mouse WFS1 protein.	Nitrogen	64-65	wolframin ER transmembrane glycoprotein	Mus musculus	88-92
15522226-8	2004	These data indicate that ER-stress and N-glycosylation play important roles in WFS1 expression and stability, and also suggest regulatory roles for this protein in ER-stress induced cell death.	Nitrogen	39-40	wolframin ER transmembrane glycoprotein	Mus musculus	79-83
15815077-9	2004	Based on these data, we conclude that EtOH-inducible microsomal CYP isoforms (mainly CYP2E1) are responsible for binding and N-demethylation metabolism of both studied N-nitrosamines in rabbit liver microsomal system.	Nitrogen	125-126	cytochrome P450 2E1	Oryctolagus cuniculus	85-91
20643191-1	2010	We investigated the functional relationship between the soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) protein syntaxin 1A (syn 1A) and the dopamine transporter (DAT) by treating rat striatal tissue with Botulinum Neurotoxin C (BoNT/C) and co-transfecting syn 1A with DAT in non-neuronal cells, followed by analysis of DAT activity, phosphorylation, and regulation.	Nitrogen	64-65	syntaxin 1A	Rattus norvegicus	147-153
20639197-2	2010	Based on consensus sequences, the GABA(A) receptor beta2 subunit contains three potential N-linked glycosylation sites, Asn-32, Asn-104, and Asn-173.	Nitrogen	90-91	neuronal differentiation 1	Homo sapiens	51-56
15619338-6	2004	With cholestatic serum added into the HGF-induced system, differentiated cells grew into similar angular cells, and had a higher level synthesis of glycogen, triglycerides, albumin and urea nitrogen with positive ICG and FDA staining.	Nitrogen	190-198	hepatocyte growth factor	Mus musculus	38-41
15375647-6	2004	Kinetic analyses suggest that Hpa3p catalyzes the N-acetylation of D-amino acids through an ordered bi-bi mechanism, in which acetyl-CoA is the first substrate to be bound and CoA is the last product to be liberated.	Nitrogen	50-51	D-amino-acid N-acetyltransferase	Saccharomyces cerevisiae S288C	30-35
21095465-8	2010	Other properties of COMT inhibitors, like scavenging of oxygen and nitrogen radicals, may be important in antiallodynic effects found in neuropathic pain models.	Nitrogen	67-75	catechol-O-methyltransferase	Mus musculus	20-24
19811453-2	2009	In the present study, we have shown that the previously uncharacterized PDI family member TMX4 (thioredoxin-like transmembrane 4) is an N-glycosylated type I membrane protein that localizes to the ER.	Nitrogen	136-137	thioredoxin related transmembrane protein 4	Homo sapiens	90-94
20730242-1	2010	A general route for the functionalization of P(4) mediated by four-membered phosphorus-nitrogen-metal heterocycles is introduced yielding novel phosphorus-rich clusters.	Nitrogen	87-95	solute carrier family 10 member 4	Homo sapiens	45-49
19846557-0	2009	Regulation of homotypic cell-cell adhesion by branched N-glycosylation of N-cadherin extracellular EC2 and EC3 domains.	Nitrogen	55-56	cadherin 2	Homo sapiens	74-84
19846557-6	2009	A detailed study using site-directed mutagenesis demonstrated that three of the eight putative N-glycosylation sites in the N-cadherin sequence showed N-glycan expression.	Nitrogen	95-96	cadherin 2	Homo sapiens	124-134
15497989-1	2004	A series of hitherto unknown 3,4-epoxy-1,1-difluorobutenes were prepared from the readily accessible alpha,beta-epoxy ketones and these compounds were found to undergo regioselective S(N)2" reactions with hard RLi nucleophiles occurring at the highly positively charged terminal fluorine-possessing sp(2) carbon atom in quite sharp contrast to the cases of the corresponding nonfluorinated vinyloxiranes which only attained a low level of regioselectivity.	Nitrogen	185-188	ATP binding cassette subfamily E member 1	Homo sapiens	210-213
20561589-8	2010	The conserved disulfide bond-forming cysteine residues and the N-linked glycosylation sites that are preserved in CD83 are also found in SmCD83.	Nitrogen	63-64	CD83 molecule	Homo sapiens	114-118
15247221-1	2004	The role of N-glycosylation in trafficking of an apical membrane protein, the gastric H,K-ATPase beta subunit linked to yellow fluorescent protein, was analyzed in polarized LLC-PK1 cells by confocal microscopy and surface-specific biotinylation.	Nitrogen	12-13	ATPase H+/K+ transporting subunit beta	Sus scrofa	78-109
15327950-0	2004	The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.	Nitrogen	56-57	interleukin 22	Homo sapiens	32-37
15327950-5	2004	Surprisingly, the binding hot spot on IL-22 includes asparagine 54 (N54), which is post-translationally modified by N-linked glycosylation.	Nitrogen	68-69	interleukin 22	Homo sapiens	38-43
15247235-3	2004	In the presence of a good nitrogen source, TOR (target of rapamycin) maintains GLN3 and NPR1 phosphorylated and inactive by inhibiting the type 2A-related phosphatase SIT4.	Nitrogen	26-34	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	88-92
19479373-9	2009	We also show that the N-unsubstituted glucosamine residues are formed during biosynthesis of glypican-1 and that the content increased upon inhibition of polyamine synthesis.	Nitrogen	22-23	glypican 1	Homo sapiens	93-103
20118605-2	2009	Fluorescent microscopic observation of GFP-fused Avt6 revealed it to be exclusively localized to the vacuolar membrane, with the amount of Myc-tagged Avt6 significantly increased under nitrogen starvation.	Nitrogen	185-193	aspartate/glutamate transporter	Saccharomyces cerevisiae S288C	49-53
20118605-2	2009	Fluorescent microscopic observation of GFP-fused Avt6 revealed it to be exclusively localized to the vacuolar membrane, with the amount of Myc-tagged Avt6 significantly increased under nitrogen starvation.	Nitrogen	185-193	aspartate/glutamate transporter	Saccharomyces cerevisiae S288C	150-154
20118605-6	2009	Avt6 is thus involved in vacuolar amino acid compartmentalization in S. cerevisiae cells, especially under conditions of nitrogen starvation.	Nitrogen	121-129	aspartate/glutamate transporter	Saccharomyces cerevisiae S288C	0-4
15247235-5	2004	Specifically, loss of NPR1 causes nuclear translocation and activation of GLN3, but not GAT1, in nitrogen-rich conditions.	Nitrogen	97-105	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	22-26
15247235-7	2004	We also demonstrate that the E3/E4 ubiquitin-protein ligase proteins RSP5 and BUL1/2 are required for GLN3 activation under poor nitrogen conditions.	Nitrogen	129-137	ubiquitin-ubiquitin ligase BUL1	Saccharomyces cerevisiae S288C	78-84
20883167-0	2010	Amino acid mutations in the env gp90 protein that modify N-linked glycosylation of the Chinese EIAV vaccine strain enhance resistance to neutralizing antibodies.	Nitrogen	57-58	galectin 3 binding protein	Homo sapiens	32-36
15294457-10	2004	The in vivo studies suggested that CYP2D6 is not crucial to the N-dealkylation but to another metabolic step, most probably to the ring hydroxylation.	Nitrogen	64-65	cytochrome P450, family 2, subfamily d, polypeptide 4	Rattus norvegicus	35-41
19763087-5	2009	PSL1 and PSL2, respectively, encode calreticulin3 (CRT3) and UDP-glucose:glycoprotein glycosyltransferase that act in concert with STT3A-containing oligosaccharyltransferase complex in an N-glycosylation pathway in the endoplasmic reticulum.	Nitrogen	188-189	calreticulin 3	Arabidopsis thaliana	0-4
19763087-5	2009	PSL1 and PSL2, respectively, encode calreticulin3 (CRT3) and UDP-glucose:glycoprotein glycosyltransferase that act in concert with STT3A-containing oligosaccharyltransferase complex in an N-glycosylation pathway in the endoplasmic reticulum.	Nitrogen	188-189	EMS-MUTAGENIZED BRI1 SUPPRESSOR 1	Arabidopsis thaliana	9-13
19763087-5	2009	PSL1 and PSL2, respectively, encode calreticulin3 (CRT3) and UDP-glucose:glycoprotein glycosyltransferase that act in concert with STT3A-containing oligosaccharyltransferase complex in an N-glycosylation pathway in the endoplasmic reticulum.	Nitrogen	188-189	calreticulin 3	Arabidopsis thaliana	36-49
19763087-5	2009	PSL1 and PSL2, respectively, encode calreticulin3 (CRT3) and UDP-glucose:glycoprotein glycosyltransferase that act in concert with STT3A-containing oligosaccharyltransferase complex in an N-glycosylation pathway in the endoplasmic reticulum.	Nitrogen	188-189	calreticulin 3	Arabidopsis thaliana	51-55
19763087-5	2009	PSL1 and PSL2, respectively, encode calreticulin3 (CRT3) and UDP-glucose:glycoprotein glycosyltransferase that act in concert with STT3A-containing oligosaccharyltransferase complex in an N-glycosylation pathway in the endoplasmic reticulum.	Nitrogen	188-189	staurosporin and temperature sensitive 3-like A	Arabidopsis thaliana	131-136
19123069-11	2009	Since, Dof transcription factor(s) have been previously reported to control the expression of genes involved nitrogen assimilation i.e., GS and GOGAT and may be the elevated expression of Dof 1 at the grain filling stage over expresses the GS and GOGAT genes thereby prolonging their activities.	Nitrogen	109-117	dof zinc finger protein 4	Triticum aestivum	188-193
19828315-6	2009	Lysosomal membrane proteins Lamp1 and Lamp2 show increased molecular weights in patients" myoblasts due to differential N-glycosylation.	Nitrogen	120-121	lysosomal associated membrane protein 2	Homo sapiens	38-43
15319333-0	2004	CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.	Nitrogen	61-62	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	20-27
15319483-11	2004	Two hypotheses are discussed to explain these results: (1) NRT2.1 is upregulated by a NO(3)(-) demand signaling, indirectly triggered by lack of NRT1.1-mediated uptake, which overrides feedback repression by N metabolites, and (2) NRT1.1 plays a more direct signaling role, and its transport activity generates an unknown signal required for NRT2.1 repression by N metabolites.	Nitrogen	59-60	nitrate transporter 1.1	Arabidopsis thaliana	231-235
15305215-2	2004	NMR analysis clearly indicated that the 2Dpy-containing tripeptides except the peptide in which AA1, AA3 = Aib, adopt a unique conformation with two intramolecular hydrogen bonds between 2Dpy-NH and a pyridine nitrogen and between AA3-NH and another pyridine nitrogen.	Nitrogen	210-218	ANIB1	Homo sapiens	107-110
19683424-3	2009	The nitrogen doping accelerated the electron transfer from electrode surface to the immobilized GOx, leading to the direct electrochemistry of GOx.	Nitrogen	4-12	hydroxyacid oxidase 1	Homo sapiens	96-99
19683424-3	2009	The nitrogen doping accelerated the electron transfer from electrode surface to the immobilized GOx, leading to the direct electrochemistry of GOx.	Nitrogen	4-12	hydroxyacid oxidase 1	Homo sapiens	143-146
20883167-3	2010	Genetic comparisons among parental and attenuated strains found that vaccine strains contained amino acid substitutions/deletions in gp90 that resulted in a loss of three potential N-linked glycosylation sites, designated g5, g9, and g10.	Nitrogen	181-182	galectin 3 binding protein	Homo sapiens	133-137
20707320-0	2010	Dinitrogen complexation and extent of N[triple bond]N activation within the group 6 "end-on-bridged" dinuclear complexes, {(eta5-C5Me5)M[N(i-Pr)C(Me)N(i-Pr)]}2(mu-eta1:eta1-N2) (M = Mo and W).	Nitrogen	0-10	secreted phosphoprotein 1	Homo sapiens	163-167
19757795-0	2009	Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes.	Nitrogen	32-40	synemin	Homo sapiens	13-16
15177347-6	2004	By applying efficient techniques to concentrate noble gases from nitrogen, minimum detectable activity concentrations below 1 microBq/m3 of nitrogen (STP) have been reached for both nuclides.	Nitrogen	65-73	thyroid hormone receptor interactor 10	Homo sapiens	150-153
15177347-6	2004	By applying efficient techniques to concentrate noble gases from nitrogen, minimum detectable activity concentrations below 1 microBq/m3 of nitrogen (STP) have been reached for both nuclides.	Nitrogen	140-148	thyroid hormone receptor interactor 10	Homo sapiens	150-153
20707320-0	2010	Dinitrogen complexation and extent of N[triple bond]N activation within the group 6 "end-on-bridged" dinuclear complexes, {(eta5-C5Me5)M[N(i-Pr)C(Me)N(i-Pr)]}2(mu-eta1:eta1-N2) (M = Mo and W).	Nitrogen	0-10	secreted phosphoprotein 1	Homo sapiens	168-172
15142597-7	2004	The determination of biosensors indicates that the response current of the biosensor prepared by template process decreases only by about 18% for 60 days, but that prepared by two-step process decreases by approximately 39% for 40 h. The uricase in PANI-uricase biosensor prepared by template process mainly interacts with the nitrogen linked to the quinoid ring.	Nitrogen	327-335	urate oxidase (pseudogene)	Homo sapiens	238-245
19772319-5	2009	Reduction of a more soluble analogue of TPZ, in redox equilibrium with its 1-oxide derivative, led to spin trapping of both a carbon-centered radical and a nitrogen-centered radical by N-tert-butyl-alpha-phenylnitrone (PBN).	Nitrogen	156-164	spindlin 1	Homo sapiens	102-106
15142597-7	2004	The determination of biosensors indicates that the response current of the biosensor prepared by template process decreases only by about 18% for 60 days, but that prepared by two-step process decreases by approximately 39% for 40 h. The uricase in PANI-uricase biosensor prepared by template process mainly interacts with the nitrogen linked to the quinoid ring.	Nitrogen	327-335	urate oxidase (pseudogene)	Homo sapiens	254-261
20573835-6	2010	Mutagenesis indicated that a single N-linked glycosylation site, N330, was critical for the specific interactions between MBL and SARS-S.	Nitrogen	36-37	mannose binding lectin 2	Homo sapiens	122-125
15225646-2	2004	Here, we show that the mouse GFRalpha4 is a functional, N-glycosylated, glycosylphosphatidylinositol (GPI)-anchored protein, which mediates persephin (PSPN)-induced phosphorylation of RET, but has an almost undetectable capacity to recruit RET into the 0.1% Triton X-100 insoluble membrane fraction.	Nitrogen	56-57	glial cell line derived neurotrophic factor family receptor alpha 4	Mus musculus	29-38
19745841-1	2009	The vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) tetanus neurotoxin-insensitive vesicle-associated membrane protein (TI-VAMP/VAMP7) was previously shown to mediate an exocytic pathway involved in neurite growth, but its regulation is still largely unknown.	Nitrogen	22-23	vesicle associated membrane protein 7	Homo sapiens	160-167
19745841-1	2009	The vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) tetanus neurotoxin-insensitive vesicle-associated membrane protein (TI-VAMP/VAMP7) was previously shown to mediate an exocytic pathway involved in neurite growth, but its regulation is still largely unknown.	Nitrogen	22-23	vesicle associated membrane protein 7	Homo sapiens	168-173
15087449-2	2004	Immunoblot analysis and pulse-chase metabolic labeling revealed that hephaestin is synthesized as a single-chain polypeptide modified by N-linked glycosylation to a mature 161-kDa species.	Nitrogen	137-138	hephaestin	Homo sapiens	69-79
20700484-1	2010	NPRL2, one of the tumor suppressor genes residing in a 120-kb homozygous deletion region of human chromosome band 3p21.3, has a high degree of amino acid sequence homology with the nitrogen permease regulator 2 (NPR2) yeast gene, and mutations of NPRL2 in yeast cells are associated with resistance to cisplatin-mediated cell killing.	Nitrogen	181-189	NPR2 like, GATOR1 complex subunit	Homo sapiens	0-5
15136740-0	2004	Metabolic engineering with Dof1 transcription factor in plants: Improved nitrogen assimilation and growth under low-nitrogen conditions.	Nitrogen	73-81	DOF zinc finger protein 1	Arabidopsis thaliana	27-31
15136740-0	2004	Metabolic engineering with Dof1 transcription factor in plants: Improved nitrogen assimilation and growth under low-nitrogen conditions.	Nitrogen	116-124	DOF zinc finger protein 1	Arabidopsis thaliana	27-31
15136740-2	2004	Here, we apply the plant-specific Dof1 transcription factor to improve nitrogen assimilation, the essential metabolism including the primary assimilation of ammonia to carbon skeletons to biosynthesize amino acids and other organic compounds involving nitrogen in plants.	Nitrogen	71-79	DOF zinc finger protein 1	Arabidopsis thaliana	34-38
15136740-2	2004	Here, we apply the plant-specific Dof1 transcription factor to improve nitrogen assimilation, the essential metabolism including the primary assimilation of ammonia to carbon skeletons to biosynthesize amino acids and other organic compounds involving nitrogen in plants.	Nitrogen	252-260	DOF zinc finger protein 1	Arabidopsis thaliana	34-38
15136740-5	2004	Furthermore, elementary analysis revealed that the nitrogen content increased in the Dof1 transgenic plants (approximately 30%), indicating promotion of net nitrogen assimilation.	Nitrogen	51-59	DOF zinc finger protein 1	Arabidopsis thaliana	85-89
15136740-5	2004	Furthermore, elementary analysis revealed that the nitrogen content increased in the Dof1 transgenic plants (approximately 30%), indicating promotion of net nitrogen assimilation.	Nitrogen	157-165	DOF zinc finger protein 1	Arabidopsis thaliana	85-89
15136740-6	2004	Most significantly, the Dof1 transgenic plants exhibit improved growth under low-nitrogen conditions, an agronomically important trait.	Nitrogen	81-89	DOF zinc finger protein 1	Arabidopsis thaliana	24-28
15004194-4	2004	CD55-deficient (CD55(-/-)), but not CD59-deficient (CD59(-/-)), mice exhibited increased renal IRI as indicated by significantly elevated blood urea nitrogen levels, histological scores, and neutrophil infiltration.	Nitrogen	149-157	CD55 molecule, decay accelerating factor for complement	Mus musculus	0-4
19665949-1	2009	Nitrogen-containing bisphosphonates (N-BPs) are shown to inhibit a key enzyme of intracellular mevalonate pathway, FPP synthase, leading to intracellular accumulation of pathway metabolites isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	115-127
19339218-1	2009	Phosphomannomutase (PMM2, Mannose-6-P--&gt; Mannose-1-P) deficiency is the most frequent glycosylation disorder affecting the N-glycosylation pathway.	Nitrogen	126-127	phosphomannomutase 2	Homo sapiens	20-24
19621239-0	2009	The endogenous GL3, but not EGL3, gene is necessary for anthocyanin accumulation as induced by nitrogen depletion in Arabidopsis rosette stage leaves.	Nitrogen	95-103	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	15-18
19621239-2	2009	In response to nitrogen depletion, the MYB genes PAP1/PAP2 (production of anthocyanin pigment 1/2) and GL3 are strongly induced, and anthocyanin synthesis is activated in seedlings and rosette stage plants.	Nitrogen	15-23	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	103-106
19734434-6	2009	Interestingly, nrt1.7 mutants showed growth retardation when external nitrogen was depleted.	Nitrogen	70-78	nitrate transporter 1.1	Arabidopsis thaliana	15-19
20700484-1	2010	NPRL2, one of the tumor suppressor genes residing in a 120-kb homozygous deletion region of human chromosome band 3p21.3, has a high degree of amino acid sequence homology with the nitrogen permease regulator 2 (NPR2) yeast gene, and mutations of NPRL2 in yeast cells are associated with resistance to cisplatin-mediated cell killing.	Nitrogen	181-189	NPR2 like, GATOR1 complex subunit	Homo sapiens	247-252
20388532-8	2010	Deglycosylation experiments indicated that occupancy of a singular N-glycosylation site was required for activity of HvXET6.	Nitrogen	67-68	XET6	Hordeum vulgare	117-123
19420132-0	2009	Selective role of sulfotransferase 2A1 (SULT2A1) in the N-sulfoconjugation of quinolone drugs in humans.	Nitrogen	56-57	sulfotransferase family 2A member 1	Homo sapiens	18-38
19420132-0	2009	Selective role of sulfotransferase 2A1 (SULT2A1) in the N-sulfoconjugation of quinolone drugs in humans.	Nitrogen	56-57	sulfotransferase family 2A member 1	Homo sapiens	40-47
19420132-5	2009	Kinetic analyses demonstrated that HLC-mediated N-sulfations were monophasic for all of the substrates examined with apparent K(m) values comparable to those mediated by hSULT2A1.	Nitrogen	48-49	sulfotransferase family 2A member 1	Homo sapiens	170-178
19420132-6	2009	The K(m) values for N-sulfation mediated by hSULT2A1 were as follows: 1.08 +/- 0.03 mM for ciprofloxacin, 0.53 +/- 0.01 mM for moxifloxacin, 0.19 +/- 0.01 mM for garenoxacin, 0.054 +/- 0.001 mM for desipramine, and 2.32 +/- 0.12 mM for metoclopramide.	Nitrogen	20-21	sulfotransferase family 2A member 1	Homo sapiens	44-52
15043610-8	2004	The normalized protein equivalent nitrogen appearance (nPNA) increased from 1.19 +/- 0.34 g/kg/day with conventional hemodialysis to 1.34 +/- 0.43 g/kg/day sDHD(year) and 1.37 +/- 0.37 g/kg/day sDHD(end).	Nitrogen	34-42	succinate dehydrogenase complex subunit D	Homo sapiens	156-160
14960317-3	2004	Here, we show that PDR5 promoter activity is dramatically reduced when cells stop growing due to a limitation of glucose or nitrogen or when they approach stationary phase.	Nitrogen	124-132	ATP-binding cassette multidrug transporter PDR5	Saccharomyces cerevisiae S288C	19-23
20406859-1	2010	N-acetyltransferase 1 (NAT1)-mediated N-acetylation in keratinocytes is an important detoxification pathway for the hair dye ingredient para-phenylenediamine (PPD).	Nitrogen	0-1	N-acetyltransferase 1	Homo sapiens	23-27
14761847-9	2004	Interestingly, oxidized base-specific DNA N-glycosylases, Fpg, Nth, Ntg1, Ntg2, Ogg1, hNth1 and hOgg1, cannot repair Ca in DNA.	Nitrogen	39-40	nth like DNA glycosylase 1	Homo sapiens	86-91
21583670-1	2009	The conformation of the N-H bond in the structure of the title compound, C(8)H(7)BrClNO, is syn to the 2-chloro substituent in the aniline ring and anti to both the C=O and C-Br bonds in the side chain, similar to that observed in 2-chloro-N-(2-chloro-phen-yl)acetamide.	Nitrogen	24-25	synemin	Homo sapiens	92-95
20307660-6	2010	Double-knockouts lived 47% longer, mice with 50% DDR1 lived 29% longer and showed improved renal function (reduction in proteinuria and blood urea nitrogen) compared to animals with 100% DDR1 expression.	Nitrogen	147-155	discoidin domain receptor family, member 1	Mus musculus	49-53
19504480-3	2009	In a subsequent experiment, benzoic acid was mixed with silver nitrate to mimic the N:H ratio of organic-rich nitrogen compounds such as cellulose nitrate and RDX.	Nitrogen	110-118	radixin	Homo sapiens	159-162
20457894-10	2010	Altogether, these observations suggest that Mgat1-dependent N-glycosylation plays an important role in the control of Drosophila life span.	Nitrogen	60-61	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Drosophila melanogaster	44-49
21582899-2	2009	The conformation of the N-H bond in the structure is syn to the C=O bond in one of the mol-ecules and anti in the other.	Nitrogen	24-25	synemin	Homo sapiens	53-56
19233551-2	2009	Nitrogen-containing bisphosphonates (N-BPs) are inhibitors of farnesyl diphosphate (FPP) synthase as well as chelators of divalent cations.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	62-97
20372747-0	2010	Activation and cleavage of the N-N bond in side-on bound [L2M-NN-ML2] (L = NH2, NMe2, N(i)Pr2, C5H5, C5Me4H) dinitrogen complexes of transition metals from groups 4 through 9.	Nitrogen	31-32	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	80-84
19143999-0	2009	Phospholipase D epsilon and phosphatidic acid enhance Arabidopsis nitrogen signaling and growth.	Nitrogen	66-74	phospholipase D alpha 1	Arabidopsis thaliana	0-15
19143999-6	2009	OE and KO of PLD epsilon had opposite effects on lateral root elongation in response to nitrogen.	Nitrogen	88-96	phospholipase D alpha 1	Arabidopsis thaliana	13-16
20372747-0	2010	Activation and cleavage of the N-N bond in side-on bound [L2M-NN-ML2] (L = NH2, NMe2, N(i)Pr2, C5H5, C5Me4H) dinitrogen complexes of transition metals from groups 4 through 9.	Nitrogen	33-34	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	80-84
20372747-1	2010	The activation and cleavage of the N-N bond in side-on bound [L2M-NN-ML2] (L = NH2, NMe2, N(i)Pr2, C5H5, C5Me4H) dinitrogen complexes of transition metals in groups 4 through 9 have been investigated using density functional theory.	Nitrogen	35-36	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	84-88
19637563-1	2009	OBJECTIVE: We studied the role of the nitrogen fixation gene PST1305 located within the nitrogen fixation island of Pseudomonas stutzeri A1501.	Nitrogen	38-46	PST_RS06645	Pseudomonas stutzeri A1501	61-68
19637563-1	2009	OBJECTIVE: We studied the role of the nitrogen fixation gene PST1305 located within the nitrogen fixation island of Pseudomonas stutzeri A1501.	Nitrogen	88-96	PST_RS06645	Pseudomonas stutzeri A1501	61-68
19637563-4	2009	Real-Time PCR was applied to compare the expression level of PST1305 gene between optimal and non-nitrogen fixating conditions.	Nitrogen	98-106	PST_RS06645	Pseudomonas stutzeri A1501	61-68
19637563-7	2009	In contrast to the nitrogen excess conditions, expression of PST1305 under nitrogen-fixing conditions was significantly upregulated for 38.7-fold.	Nitrogen	19-27	PST_RS06645	Pseudomonas stutzeri A1501	61-68
19637563-7	2009	In contrast to the nitrogen excess conditions, expression of PST1305 under nitrogen-fixing conditions was significantly upregulated for 38.7-fold.	Nitrogen	75-83	PST_RS06645	Pseudomonas stutzeri A1501	61-68
20372747-1	2010	The activation and cleavage of the N-N bond in side-on bound [L2M-NN-ML2] (L = NH2, NMe2, N(i)Pr2, C5H5, C5Me4H) dinitrogen complexes of transition metals in groups 4 through 9 have been investigated using density functional theory.	Nitrogen	37-38	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	84-88
19637563-9	2009	PST1305 gene might participate in biological nitrogen fixation by involving in the electron transport or the oxygen protection mechanism of nitrogenase.	Nitrogen	45-53	PST_RS06645	Pseudomonas stutzeri A1501	0-7
20056725-5	2010	Finally, this isozyme was demonstrated to be UDP-glucuronosyltransferase (UGT) 1A4, with the direct evidence that recombinant UGT1A4 exhibited predominant and exclusive activity on SEN N-glucuronidation.	Nitrogen	183-184	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	45-82
19322936-2	2009	In yeast (Saccharomyces cerevisiae), the regulation of three MAP kinase pathways responding to pheromones (Fus3 pathway), carbon/nitrogen starvation (Kss1 pathway), and high osmolarity/osmotic stress (Hog1 pathway) is the subject of intensive research.	Nitrogen	129-137	mitogen-activated serine/threonine-protein kinase KSS1	Saccharomyces cerevisiae S288C	150-154
19322936-7	2009	When testing simultaneous stimulations by low nitrogen and pheromones through the Kss1 and Fus3 pathways, respectively, the low nitrogen response dominates over the pheromone response.	Nitrogen	46-54	mitogen-activated serine/threonine-protein kinase KSS1	Saccharomyces cerevisiae S288C	82-86
19322936-7	2009	When testing simultaneous stimulations by low nitrogen and pheromones through the Kss1 and Fus3 pathways, respectively, the low nitrogen response dominates over the pheromone response.	Nitrogen	128-136	mitogen-activated serine/threonine-protein kinase KSS1	Saccharomyces cerevisiae S288C	82-86
20056725-5	2010	Finally, this isozyme was demonstrated to be UDP-glucuronosyltransferase (UGT) 1A4, with the direct evidence that recombinant UGT1A4 exhibited predominant and exclusive activity on SEN N-glucuronidation.	Nitrogen	183-184	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	126-132
20056725-7	2010	The exclusive role of UGT1A4 on SEN N-glucuronidation was strengthened additionally by its inhibitory kinetic study in which the selective inhibitor of UGT1A4 showed a similar inhibition pattern and K(i) values in both HLM and recombinant UGT1A4 systems.	Nitrogen	34-35	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	22-28
19342661-0	2009	N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase.	Nitrogen	0-1	tyrosinase	Homo sapiens	79-89
20056725-7	2010	The exclusive role of UGT1A4 on SEN N-glucuronidation was strengthened additionally by its inhibitory kinetic study in which the selective inhibitor of UGT1A4 showed a similar inhibition pattern and K(i) values in both HLM and recombinant UGT1A4 systems.	Nitrogen	34-35	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	152-158
20056725-7	2010	The exclusive role of UGT1A4 on SEN N-glucuronidation was strengthened additionally by its inhibitory kinetic study in which the selective inhibitor of UGT1A4 showed a similar inhibition pattern and K(i) values in both HLM and recombinant UGT1A4 systems.	Nitrogen	34-35	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	152-158
20107545-6	2009	Using a site directed mutagenesis method, plasmid vectors for Tim-3-Ig N-glycosylation mutant expression were produced.	Nitrogen	71-72	hepatitis A virus cellular receptor 2	Homo sapiens	62-67
19818407-0	2010	Identification of the N-glycosylation sites on recombinant bovine CD38 expressed in Pichia pastoris: their impact on enzyme stability and catalytic activity.	Nitrogen	22-23	CD38 molecule	Bos taurus	66-70
20107545-10	2009	Further, three N-glycosylation mutant forms (N53Q, N100Q, N53/100Q) of Tim-3-Ig showed similar binding activities to those of wild type glycosylated Tim-3-Ig.	Nitrogen	15-16	hepatitis A virus cellular receptor 2	Homo sapiens	71-76
19206533-4	2009	To circumvent the low reactivity of the C-3 position, we developed a "SEM switch", which transposes the SEM-protecting group from one nitrogen to the other in one step, and in the process transforms the unreactive C-3 position to the reactive C-5 position.	Nitrogen	134-142	complement C3	Homo sapiens	40-43
19206533-4	2009	To circumvent the low reactivity of the C-3 position, we developed a "SEM switch", which transposes the SEM-protecting group from one nitrogen to the other in one step, and in the process transforms the unreactive C-3 position to the reactive C-5 position.	Nitrogen	134-142	complement C3	Homo sapiens	214-217
19818407-1	2010	Bovine CD38, a type II glycoprotein, contains two potential N-glycosylation sites (Asn-201 and Asn-268) in its extracellular domain.	Nitrogen	60-61	CD38 molecule	Bos taurus	7-11
20305092-1	2010	Dose-response expression of kidney injury molecule-1 (KIM-1) gene in kidney cortex and its correlation with morphology and traditional biomarkers of nephrotoxicity (plasma creatinine and blood urea nitrogen, BUN) or segment-specific marker of proximal tubule injury (kidney glutamine synthetase, GSK) were studied in male rats treated with proximal tubule segment-specific nephrotoxicants.	Nitrogen	198-206	hepatitis A virus cellular receptor 1	Rattus norvegicus	28-52
19200740-2	2009	The scaffold is not normally associated with chemoprevention in spite of the presence of a nitrogen-linked Michael acceptor moiety that may predispose members to induction of NQO1, a widely used biomarker of chemopreventive potential.	Nitrogen	91-99	NAD(P)H dehydrogenase, quinone 1	Mus musculus	175-179
20305092-1	2010	Dose-response expression of kidney injury molecule-1 (KIM-1) gene in kidney cortex and its correlation with morphology and traditional biomarkers of nephrotoxicity (plasma creatinine and blood urea nitrogen, BUN) or segment-specific marker of proximal tubule injury (kidney glutamine synthetase, GSK) were studied in male rats treated with proximal tubule segment-specific nephrotoxicants.	Nitrogen	198-206	hepatitis A virus cellular receptor 1	Rattus norvegicus	54-59
19190950-2	2009	The purpose of this work was to investigate the effects of two membrane n-3 long chain polyunsaturated fatty acids (n-3 PUFAs), EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) compared to n-6 PUFA, ARA (arachidonic acid), on the activation of endothelial NO synthase (eNOS) by histamine in Ea hy 926 endothelial cells incubated during 24 h in the presence or the absence of LysoPtdCho.	Nitrogen	33-34	pumilio RNA binding family member 3	Homo sapiens	120-124
20099820-6	2010	Simulation and least-squares fitting of orientation-selective Ka- and Q-band ENDOR, 1D ESEEM, and HYSCORE spectra of (14)N and (15)N-labeled mitoNEET yield the principal values and orientations of both the hyperfine tensor ((14)N, A(iso) = -6.25 MHz, T = -0.94 MHz) and the quadrupolar tensor (e(2)Qq/h = -2.47 MHz, eta = 0.38) of the ligating histidine nitrogen N(delta).	Nitrogen	354-362	CDGSH iron sulfur domain 1	Homo sapiens	141-149
18826430-6	2009	Here we report that Arabidopsis thaliana NIN-like protein 7 (NLP7) knockout mutants constitutively show several features of nitrogen-starved plants, and that they are tolerant to drought stress.	Nitrogen	124-132	NIN like protein 7	Arabidopsis thaliana	41-59
18826430-6	2009	Here we report that Arabidopsis thaliana NIN-like protein 7 (NLP7) knockout mutants constitutively show several features of nitrogen-starved plants, and that they are tolerant to drought stress.	Nitrogen	124-132	NIN like protein 7	Arabidopsis thaliana	61-65
18826430-7	2009	We show that nlp7 mutants are impaired in transduction of the nitrate signal, and that the NLP7 expression pattern is consistent with a function of NLP7 in the sensing of nitrogen.	Nitrogen	171-179	NIN like protein 7	Arabidopsis thaliana	13-17
18826430-7	2009	We show that nlp7 mutants are impaired in transduction of the nitrate signal, and that the NLP7 expression pattern is consistent with a function of NLP7 in the sensing of nitrogen.	Nitrogen	171-179	NIN like protein 7	Arabidopsis thaliana	91-95
18826430-7	2009	We show that nlp7 mutants are impaired in transduction of the nitrate signal, and that the NLP7 expression pattern is consistent with a function of NLP7 in the sensing of nitrogen.	Nitrogen	171-179	NIN like protein 7	Arabidopsis thaliana	148-152
18826430-9	2009	We propose NLP7 as an important element of the nitrate signal transduction pathway and as a new regulatory protein specific for nitrogen assimilation in non-nodulating plants.	Nitrogen	128-136	NIN like protein 7	Arabidopsis thaliana	11-15
18978044-9	2009	These results provide insight into the mechanisms by which Crp negatively regulates genes such as luxS and ompX and provide a link between catabolite repression, quorum sensing, and nitrogen assimilation in E. coli.	Nitrogen	182-190	catabolite gene activator protein	Escherichia coli	59-62
19143230-5	2008	Milk fat proportions of conjugated linoleic acid (CLA), C18:3 c9,c12,c15, total n-3 and polyunsaturated FA (PUFA) were highest (p &lt; 0.05) with diet OC and higher in the lowlands than in the highlands.	Nitrogen	18-19	PUFA	Bos taurus	108-112
20056109-4	2010	LDLR+/+ but not LDLR-/- cells showed higher n-6 over n-3 TGRP uptake.	Nitrogen	12-13	low density lipoprotein receptor	Homo sapiens	16-20
19060393-1	2008	Deoxyribonuclease I (DNase I) is known to be a glycoprotein, and two potential N-linked glycosylation sites (N18 and N106) are known for mammalian enzymes.	Nitrogen	22-23	deoxyribonuclease 1	Homo sapiens	0-19
20004212-2	2010	Bioactivation includes N-hydroxylation catalyzed by cytochrome P4501A2 (CYP1A2) followed by O-acetylation catalyzed by N-acetyltransferase 2 (NAT2).	Nitrogen	23-24	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	52-70
18702671-6	2008	Expression studies identified genes involved in nitrogen metabolism and nitric oxide (NO) generation as potential targets of negative regulation by WRKY27.	Nitrogen	48-56	WRKY DNA-binding protein 27	Arabidopsis thaliana	148-154
20004212-2	2010	Bioactivation includes N-hydroxylation catalyzed by cytochrome P4501A2 (CYP1A2) followed by O-acetylation catalyzed by N-acetyltransferase 2 (NAT2).	Nitrogen	23-24	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	72-78
18926711-3	2008	In this report, we describe SAR in this series of compounds and show that the 3,4-methylenedioxybenzoyl (piperonyloyl) group on the nitrogen of piperidine and lipophilic substitution at the C(6)-position of pyrimidine are important for this inhibitory activity.	Nitrogen	132-140	sarcosine dehydrogenase	Homo sapiens	28-31
19592704-5	2010	All of the putative N-linked glycosylation sites (Asn(270), Asn(367), and Asn(389)) of NCEH are glycosylated.	Nitrogen	20-21	neutral cholesterol ester hydrolase 1	Homo sapiens	87-91
18941661-0	2008	Novel ruthenium(ii) complexes containing the N-phosphorylated iminophosphorane-phosphine ligand Ph(2)PCH(2)P{[double bond, length as m-dash]NP([double bond, length as m-dash]O)(OEt)(2)}Ph(2): a new coordination mode of its methanide anion.	Nitrogen	0-1	polyhomeotic homolog 2	Homo sapiens	96-101
16281877-6	2004	Biochemical characterization of the p200 molecule revealed a noncollagenous N-glycosylated acidic protein with an isoelectric point of approximately 5.5.	Nitrogen	76-77	AT-rich interaction domain 2	Homo sapiens	36-40
20002318-6	2010	Contrary to previous studies, leaf nitrogen concentration was similar in C(4) and C(3) types.	Nitrogen	35-43	complement C4A (Rodgers blood group)	Homo sapiens	73-77
19915009-4	2010	We have mutated the asparagines of all nine functional N-glycosylation sites of gp130 to glutamine and systematically analyzed the consequences of deleted N-glycosylation (dNG) in both cellular gp130 and in a soluble gp130-IgG1-Fc fusion protein (sgp130Fc).	Nitrogen	55-56	interleukin 6 cytokine family signal transducer	Homo sapiens	80-85
17564315-1	2004	N-acetylation plays an important role in the metabolism of arylamine drugs and carcinogens and is catalyzed by cytosolic N-acetyltransferase (NAT).	Nitrogen	0-1	bromodomain containing 2	Homo sapiens	121-140
17564315-1	2004	N-acetylation plays an important role in the metabolism of arylamine drugs and carcinogens and is catalyzed by cytosolic N-acetyltransferase (NAT).	Nitrogen	0-1	bromodomain containing 2	Homo sapiens	142-145
21140004-5	2010	Here, we examined the influence of inhibition of N-glycosylation on expression of E1 and E2.	Nitrogen	49-50	small nucleolar RNA, H/ACA box 73A	Homo sapiens	82-91
14565980-3	2003	Because conserved cell cycle regulators, the mitotic cyclin-dependent kinase Clb2/Cdc28, and its inhibitor Swe1 were found to be involved in both nitrogen starvation- and short chain alcohol-induced filamentous differentiation, they were identified as components of the core mechanism for filamentous differentiation.	Nitrogen	146-154	B-type cyclin CLB2	Saccharomyces cerevisiae S288C	77-81
19884339-8	2010	Identifying carriage of this N residue in ECL-2 as being important for native CPE binding helps to explain why only certain claudins can serve as CPE receptors.	Nitrogen	29-30	cpe	Clostridium perfringens	78-81
14599209-4	2003	To define the potential reactions of Met radical cations in beta AP, we have performed time-resolved UV spectroscopic and conductivity studies with small model peptides, which show for the first time that (i) Met radical cations in peptides can be stabilized through bond formation with either the oxygen or the nitrogen atoms of adjacent peptide bonds; (ii) the formation of sulfur-oxygen bonds is kinetically preferred, but on longer time scales, sulfur-oxygen bonds convert into sulfur-nitrogen bonds in a pH-dependent manner; and (iii) ultimately, sulfur-nitrogen bonded radicals may transform intramolecularly into carbon-centered radicals located on the (alpha)C moiety of the peptide backbone.	Nitrogen	312-320	serpin family F member 2	Homo sapiens	60-67
14599209-4	2003	To define the potential reactions of Met radical cations in beta AP, we have performed time-resolved UV spectroscopic and conductivity studies with small model peptides, which show for the first time that (i) Met radical cations in peptides can be stabilized through bond formation with either the oxygen or the nitrogen atoms of adjacent peptide bonds; (ii) the formation of sulfur-oxygen bonds is kinetically preferred, but on longer time scales, sulfur-oxygen bonds convert into sulfur-nitrogen bonds in a pH-dependent manner; and (iii) ultimately, sulfur-nitrogen bonded radicals may transform intramolecularly into carbon-centered radicals located on the (alpha)C moiety of the peptide backbone.	Nitrogen	489-497	serpin family F member 2	Homo sapiens	60-67
14599209-4	2003	To define the potential reactions of Met radical cations in beta AP, we have performed time-resolved UV spectroscopic and conductivity studies with small model peptides, which show for the first time that (i) Met radical cations in peptides can be stabilized through bond formation with either the oxygen or the nitrogen atoms of adjacent peptide bonds; (ii) the formation of sulfur-oxygen bonds is kinetically preferred, but on longer time scales, sulfur-oxygen bonds convert into sulfur-nitrogen bonds in a pH-dependent manner; and (iii) ultimately, sulfur-nitrogen bonded radicals may transform intramolecularly into carbon-centered radicals located on the (alpha)C moiety of the peptide backbone.	Nitrogen	489-497	serpin family F member 2	Homo sapiens	60-67
12882965-2	2003	In repair of the N-alkylated purine base lesion, for example, alkyl adenine DNA glycosylase (Aag) recognizes and removes the base, and DNA polymerase beta (beta-pol) contributes the gap tailoring and DNA synthesis steps.	Nitrogen	17-18	N-methylpurine DNA glycosylase	Homo sapiens	62-91
12882965-2	2003	In repair of the N-alkylated purine base lesion, for example, alkyl adenine DNA glycosylase (Aag) recognizes and removes the base, and DNA polymerase beta (beta-pol) contributes the gap tailoring and DNA synthesis steps.	Nitrogen	17-18	N-methylpurine DNA glycosylase	Homo sapiens	93-96
19884339-8	2010	Identifying carriage of this N residue in ECL-2 as being important for native CPE binding helps to explain why only certain claudins can serve as CPE receptors.	Nitrogen	29-30	cpe	Clostridium perfringens	146-149
14521407-4	2003	The SAR of the functionality on the proline nitrogen has shown that derivatives of para-substituted phenyl ureas &gt; para-substituted phenyl sulfonamides &gt; para-substituted phenyl carboxamide for activity against HCMV deltaAla protease, producing para-substituted phenyl ureas with single figure nM potency (K(i)) against the viral enzyme.	Nitrogen	44-52	sarcosine dehydrogenase	Homo sapiens	4-7
20007685-8	2010	Since VTC1 encodes a GDP-mannose pyrophosphorylase, an enzyme generating GDP-mannose for AA biosynthesis and protein N-glycosylation, it was also tested whether protein N-glycosylation is affected in vtc1-1.	Nitrogen	117-118	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	6-10
14521407-5	2003	The SAR of the functionality on the lactam nitrogen has defined the steric and electronic requirements for high human plasma stability while retaining good activity against HCMV protease.	Nitrogen	43-51	sarcosine dehydrogenase	Homo sapiens	4-7
14553833-8	2003	CONCLUSIONS: These results suggest that the activation of PKC/Raf/MEK/ERK-mediated events controlling E2F-1 gene expression by N-LDL may represent an important mechanism in the regulation of HECs proliferation during normal and pathological processes.	Nitrogen	2-3	Raf-1 proto-oncogene, serine/threonine kinase S homeolog	Xenopus laevis	62-65
20007685-10	2010	Our data suggest that NH(4)(+) hypersensitivity in vtc1-1 is caused by disturbed N-glycosylation and that it is associated with auxin and ethylene homeostasis and/or nitric oxide signalling.	Nitrogen	22-23	Glucose-1-phosphate adenylyltransferase family protein	Arabidopsis thaliana	51-57
20807649-3	2010	ATCS is caused by homozygous nonsense and missense mutations in CHST14 which encodes an N-acetylgalactosamine 4-O-sulfotransferase 1 (D4ST1) that catalyzes the 4-O-sulfation of N-acetylgalactosamine in the repeating iduronic acid-alpha-1,3-N-acetylgalactosamine disaccharide sequence to form dermatan sulfate (DS).	Nitrogen	88-89	carbohydrate sulfotransferase 14	Homo sapiens	64-70
12975335-10	2003	The polymorphism of CYP2C19 plays an important role in the N- demethylation of citalopram in vivo.	Nitrogen	59-60	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	20-27
20807649-3	2010	ATCS is caused by homozygous nonsense and missense mutations in CHST14 which encodes an N-acetylgalactosamine 4-O-sulfotransferase 1 (D4ST1) that catalyzes the 4-O-sulfation of N-acetylgalactosamine in the repeating iduronic acid-alpha-1,3-N-acetylgalactosamine disaccharide sequence to form dermatan sulfate (DS).	Nitrogen	88-89	carbohydrate sulfotransferase 14	Homo sapiens	134-139
14583137-6	2003	Hypoxia (5% CO(2)/95% N(2)) could markedly increase VEGF protein expression.	Nitrogen	22-27	vascular endothelial growth factor A	Oryctolagus cuniculus	52-56
20024105-4	2009	Incorporation of nitrogen into the phenolic ring of ApAP was also found to decrease its efficacy as an inhibitor of prostaglandin biosynthesis by ovine COX-1 (oCOX-1).	Nitrogen	17-25	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	152-157
12860997-11	2003	During import into the ER through the Sec61p channel, many proteins are N-glycosylated before translocation is completed.	Nitrogen	72-73	SEC61 translocon subunit alpha 1	Homo sapiens	38-44
19856961-10	2009	A comparison of the unliganded cis-CaaD crystal structure with that of an inactivated cis-CaaD where the prolyl nitrogen of Pro-1 is covalently attached to (R)-2-hydroxypropanoate provides a possible explanation for the isomerization step.	Nitrogen	112-120	lamin A/C	Homo sapiens	124-129
12734200-6	2003	CA125 is also N-glycosylated, expressing primarily high mannose and complex bisecting type N-linked glycans.	Nitrogen	14-15	mucin 16, cell surface associated	Homo sapiens	0-5
12734200-9	2003	Remarkably, the N-glycosylation profiles of CA125 and the envelope glycoprotein gp120 (derived from H9 lymphoblastoid cells chronically infected with HIV-1) are very similar.	Nitrogen	16-17	mucin 16, cell surface associated	Homo sapiens	44-49
12719423-7	2003	If N-glycosylation inhibitors prevent the association with calnexin, the TRP-2 nascent chain undergoes an accelerated degradation process.	Nitrogen	3-4	dopachrome tautomerase	Mus musculus	73-78
19839618-2	2009	The first mechanism consists of the direct dissociation (homolysis) of the carbon nitrogen bond (CH(3)C(6)H(4)NO(2) = CH(3)C(6)H(4) + NO(2)) whereas the second one is a more complex process initiated by C-H alpha attack and leading to the formation of anthranil and water (C(6)H(4)C(H)ON + H(2)O).	Nitrogen	82-90	transcription factor like 5	Homo sapiens	203-212
12860408-3	2003	Primary amino groups of Lys and Hyl were N-methylated by formaldehyde in reducing conditions or N-acetylated by sulfosuccinimidyl acetate.	Nitrogen	41-42	megakaryocyte-associated tyrosine kinase	Homo sapiens	32-35
20054137-1	2009	The condensation of ammonium and glutamate into glutamine catalyzed by glutamine synthetase (GS) is a fundamental step in nitrogen metabolism in all kingdoms of life.	Nitrogen	122-130	LOC11405318	Medicago truncatula	71-91
12837097-4	2003	Similarly, 3,4-di-tert-butylthiophene 1-(p-toluenesulfonyl)imide (3a) reacted with alkenic dienophiles at its syn-pi-face relating to the S=N bond to give [4+2] adducts in good yields.	Nitrogen	140-141	synemin	Homo sapiens	110-113
19632286-6	2009	These data suggest that the modulation of BDNF expression contributes, in part, to n-3 PUFA-induced neuroprotection in an animal model of PD.	Nitrogen	37-38	brain derived neurotrophic factor	Mus musculus	42-46
12945698-6	2003	The balance in reactivity is attributed to the additional stability obtained in the six membered cyclic compounds by a syn orientation of the two lone pairs of the cyclic nitrogen to the water attack.	Nitrogen	171-179	synemin	Homo sapiens	119-122
12945698-9	2003	The syn orientation of two electron pairs on nitrogen stabilizes the transition state of water approach to the phosphoramides by ca.	Nitrogen	45-53	synemin	Homo sapiens	4-7
12837786-1	2003	Peptide methionine sulfoxide reductase (MsrA) repairs oxidative damage to methionine residues arising from reactive oxygen species and reactive nitrogen intermediates.	Nitrogen	144-152	methionine sulfoxide reductase A	Homo sapiens	40-44
19933203-5	2009	Overexpression of each of the three genes in the absence of N/NO(3)(-) strongly suppresses the key regulators of anthocyanin synthesis PAP1 and PAP2, genes in the anthocyanin-specific part of flavonoid synthesis, as well as cyanidin- but not quercetin- or kaempferol-glycoside production.	Nitrogen	60-61	phosphatidic acid phosphatase 1	Arabidopsis thaliana	135-139
12754263-12	2003	Furthermore, signals originating from nitrogen and carbon metabolism regulate APR synergistically.	Nitrogen	38-46	APS reductase 1	Arabidopsis thaliana	78-81
12761411-4	2003	The structure refinement of HMT-C11 based on X-ray diffraction experiments indicates three distinct phases from the melting point down to liquid nitrogen temperature: phase I is not crystalline; phase II is disordered (stacking fault) and its average structure is described in space group Bmmb; phase III is partially disordered and its symmetry is P2(1)/c.	Nitrogen	145-153	histamine N-methyltransferase	Homo sapiens	28-31
12761411-4	2003	The structure refinement of HMT-C11 based on X-ray diffraction experiments indicates three distinct phases from the melting point down to liquid nitrogen temperature: phase I is not crystalline; phase II is disordered (stacking fault) and its average structure is described in space group Bmmb; phase III is partially disordered and its symmetry is P2(1)/c.	Nitrogen	145-153	RNA polymerase III subunit K	Homo sapiens	32-35
19933203-5	2009	Overexpression of each of the three genes in the absence of N/NO(3)(-) strongly suppresses the key regulators of anthocyanin synthesis PAP1 and PAP2, genes in the anthocyanin-specific part of flavonoid synthesis, as well as cyanidin- but not quercetin- or kaempferol-glycoside production.	Nitrogen	60-61	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	144-148
19779244-3	2009	This finding can be qualitatively understood in terms of a phase field model, in which the interplay of three ingredients, including free energy of the binary-component solution monolayer, phase boundary energy and surface stress, determines the final equilibrium sizes of the ordered DP-TTF and n- C(14)H(30) phases in the binary-component SAM.	Nitrogen	7-8	ras homolog family member H	Homo sapiens	288-291
12672238-3	2003	Strong interactions, especially salts bridges between the protonated nitrogens of HZ2 and the glutamic acids 209 and 297, nicely explain the high affinity of HZ2 to the KOR.	Nitrogen	69-78	opioid receptor kappa 1	Homo sapiens	169-172
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	115-116	adrenoceptor alpha 2A	Homo sapiens	19-30
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	115-116	adrenoceptor alpha 2A	Homo sapiens	256-267
12529373-6	2003	Finally, beta(1)AR/alpha(2A)AR heterodimerization was found to be markedly enhanced by a beta(1)AR point mutation (N15A) that blocks N-linked glycosylation of the beta(1)AR as well as by point mutations (N10A/N14A) that block N-linked glycosylation of the alpha(2A)AR.	Nitrogen	133-134	adrenoceptor alpha 2A	Homo sapiens	19-30
18687745-8	2008	In comparison of MET T/N ratios with the Mib-1 LI, a significant correlation was shown in DA (r = 0.63; P &lt; .005) but not in OD and OA.	Nitrogen	23-24	MIB E3 ubiquitin protein ligase 1	Homo sapiens	41-46
18725511-9	2008	For the first time, marked enantioselectivity was observed for N-demethylation and demethylenation by CYP2C19 with a preference for the S-enantiomers.	Nitrogen	63-64	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	102-109
18768906-11	2008	Besides demonstrating the conditional nature of cgl1 C5 in planta, our observations with loss-of-function alleles cgl1 C6 and cgl1-T in the stt3a-2 underglycosylation background prove that correct N-glycosylation is important for normal root growth and morphology in Arabidopsis.	Nitrogen	197-198	staurosporin and temperature sensitive 3-like A	Arabidopsis thaliana	140-145
19737555-0	2009	Site-specific N-glycosylation regulates the GPS auto-proteolysis of CD97.	Nitrogen	14-15	adhesion G protein-coupled receptor E5	Homo sapiens	68-72
18931734-1	2008	The syn-atropisomers of the title bis(tertiary amide)s were designed as six-bladed molecular propellers based on the "directing effects" of amide dipoles; the helicity of the propeller is biased to prefer one handedness upon the attachment of point chirality to the amide nitrogens to attain stronger circular-dichroism activity than for the non-propeller-shaped anti-isomers.	Nitrogen	272-281	synemin	Homo sapiens	4-7
12595154-1	2003	Arylamine N-acetyltransferase (NAT) enzymes catalyze the addition of an acetyl group from acetyl-CoA to a terminal nitrogen on a suitable substrate such as environmentally relevant compounds and pharmaceuticals.	Nitrogen	115-123	bromodomain containing 2	Homo sapiens	31-34
12723939-5	2003	These compounds also inhibited the production of NO and H2O2 induced by TNF-alpha, which suggests that the inhibition of ICAM-1 expression by the three compounds may be due to the modulated production of the reactive oxygen/nitrogen components.	Nitrogen	224-232	intercellular adhesion molecule 1	Homo sapiens	121-127
19737555-6	2009	The use of N-glycosylation inhibitors and mutants confirm site-specific N-glycosylation is an important determinant of GPS proteolysis in CD97.	Nitrogen	11-12	adhesion G protein-coupled receptor E5	Homo sapiens	138-142
18851332-1	2008	We use single-spin resonant spectroscopy to study the spin structure in the orbital excited state of a diamond nitrogen-vacancy (N-V) center at room temperature.	Nitrogen	111-119	spindlin 1	Homo sapiens	54-58
19737555-6	2009	The use of N-glycosylation inhibitors and mutants confirm site-specific N-glycosylation is an important determinant of GPS proteolysis in CD97.	Nitrogen	72-73	adhesion G protein-coupled receptor E5	Homo sapiens	138-142
19538164-4	2009	A linear skeleton with a N-containing aromatic ring attached at C3 of the top A-ring, a central pyran B-ring and a six-membered bottom C-ring with no alkylation at C7 are required for the antitumor activities of the lead compounds, a 3-pyridyl benzopyran (code name H10) and its 2-pyridyl regioisomer (code name H19).	Nitrogen	25-26	histocompatibility 10	Mus musculus	266-269
18666767-2	2008	The spectroscopic properties of the aromatic polyketimine containing 3,8-diamino-6-phenylphenanthridine and ethylene linkage in the main chain (PK1) before and after doping are dominated by an interplay of electron-donating and electron-withdrawing effects mediated by its nitrogen atom and active groups in the dopants, respectively.	Nitrogen	273-281	prokineticin 1	Homo sapiens	144-147
18534984-7	2008	Both the Shh precursor and mature protein are N-palmitoylated by Hhat, and the reaction occurs during passage through the secretory pathway.	Nitrogen	46-47	hedgehog acyltransferase	Homo sapiens	65-69
12617293-2	2003	Various combinations of volatile organic compound (VOC) and oxides of nitrogen (NOx) emission reductions were effective in lowering modeled peak 1-hr ozone concentrations.	Nitrogen	70-78	pseudopodium enriched atypical kinase 1	Homo sapiens	140-146
12576159-3	2003	Of various inorganic nitrogen sources, the highest yields of Cry11Aa and Cry4Ba proteins were obtained on (NH(4))(2)HPO(4).	Nitrogen	21-29	cry11AA	Bacillus thuringiensis serovar israelensis	61-68
19654028-2	2009	In this study we document that DR6 is an extensively posttranslationally modified transmembrane protein and that N- and O-glycosylations of amino acids in its extracellular part are mainly responsible for its approximately 40 kDa mobility shift in SDS polyacrylamide gels.	Nitrogen	113-114	TNF receptor superfamily member 21	Homo sapiens	31-34
14753529-2	2003	A 1D numerical model, IPOX, has been worked out to simulate the transfer and oxidation of dissolved organic matter and nitrogen in unsaturated sand beds.	Nitrogen	119-127	IPOX	Homo sapiens	22-26
12490797-6	2002	RESULTS: alpha-VEGF markedly enhanced CsA renal toxicity, inducing severe tubular damage and increased blood urea nitrogen.	Nitrogen	114-122	vascular endothelial growth factor A	Mus musculus	15-19
18502753-4	2008	The hXTP3-B long isoform strongly inhibited ERAD of NHK-QQQ, which lacks all of the N-glycosylation sites of NHK, but the short transcriptional variant of hXTP3-B had almost no effect.	Nitrogen	52-53	endoplasmic reticulum lectin 1	Homo sapiens	4-11
21203140-2	2008	Furthermore, the conformation of the N-H bond is syn to the ortho-chloro group in the aniline ring and the C=O bond is syn to the ortho-methyl substituent in the benzoyl ring, similar to what is observed in 2-chloro-N-(2-chloro-phen-yl)benzamide and 2-methyl-N-phenyl-benzamide.	Nitrogen	37-38	synemin	Homo sapiens	119-122
12356756-2	2002	BAP encoded an approximately 54-kDa protein with an N-terminal endoplasmic reticulum (ER) targeting sequence, two sites of N-linked glycosylation, and a C-terminal ER retention sequence.	Nitrogen	52-53	SIL1 nucleotide exchange factor	Homo sapiens	0-3
19716525-6	2009	Organic carbon and nitrogen compounds in leachate in the IAR and the CAR showed significant decreases in comparison to those in the CR.	Nitrogen	19-27	protein tyrosine phosphatase receptor type N2	Homo sapiens	57-60
12460896-0	2002	Aberrant N-glycosylation of beta1 integrin causes reduced alpha5beta1 integrin clustering and stimulates cell migration.	Nitrogen	9-10	integrin subunit beta 1	Homo sapiens	28-42
19086290-3	2008	It was hypothesized that, for a correlation between SLA and RGR, SLA needs to be associated with specific nitrogen absorption rate of roots (SAR), which counteracts the negative effect of SLA on LNCa.	Nitrogen	106-114	sarcosine dehydrogenase	Homo sapiens	141-144
17674125-10	2008	Co-composting experiments with fats and cellulose presented higher initial C/N ratio and lower nitrogen losses, 27.5 and 34.2% compared to 40% for raw sludge.	Nitrogen	77-78	chromosome 10 open reading frame 90	Homo sapiens	31-35
17674125-10	2008	Co-composting experiments with fats and cellulose presented higher initial C/N ratio and lower nitrogen losses, 27.5 and 34.2% compared to 40% for raw sludge.	Nitrogen	95-103	chromosome 10 open reading frame 90	Homo sapiens	31-35
19640223-3	2009	Berberine was found to readily fit within the binding pocket of DPP IV in a low energy orientation characterized with optimal electrostatic attractive interactions bridging the isoquinolinium positively charged nitrogen atom (berberine) and the negatively charged acidic residue of glutamic acid-205 (GLU205) of DPP IV.	Nitrogen	211-219	dipeptidyl peptidase 4	Homo sapiens	64-70
18410496-0	2008	Protein N-glycosylation determines functionality of the Saccharomyces cerevisiae cell wall integrity sensor Mid2p.	Nitrogen	8-9	Mid2p	Saccharomyces cerevisiae S288C	108-113
18410496-4	2008	The extracellular domain of Mid2p, which is crucial to sensing, is highly O- and N-glycosylated.	Nitrogen	81-82	Mid2p	Saccharomyces cerevisiae S288C	28-33
18410496-6	2008	If and how N-glycosylation is linked to Mid2p function was unknown.	Nitrogen	11-12	Mid2p	Saccharomyces cerevisiae S288C	40-45
18410496-10	2008	However, non-N-glycosylated Mid2p fails to perceive cell wall challenges.	Nitrogen	13-14	Mid2p	Saccharomyces cerevisiae S288C	28-33
12198133-5	2002	Mutations in CWH8 result in the accumulation of Dol-P-P, deficiency in lipid intermediate synthesis, defective protein N-glycosylation, and a reduced growth rate.	Nitrogen	119-120	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	13-17
12198133-6	2002	A cDNA (DOLPP1, GenBank accession number AB030189) from mouse brain encoding a homologue of the yeast CWH8 gene is now shown to complement the defects in growth and protein N-glycosylation, and to correct the accumulation of Dol-P-P in the cwh8Delta yeast mutant.	Nitrogen	4-5	dolichyl pyrophosphate phosphatase 1	Mus musculus	8-14
12198133-6	2002	A cDNA (DOLPP1, GenBank accession number AB030189) from mouse brain encoding a homologue of the yeast CWH8 gene is now shown to complement the defects in growth and protein N-glycosylation, and to correct the accumulation of Dol-P-P in the cwh8Delta yeast mutant.	Nitrogen	4-5	dolichyl pyrophosphate phosphatase 1	Mus musculus	41-49
12198133-6	2002	A cDNA (DOLPP1, GenBank accession number AB030189) from mouse brain encoding a homologue of the yeast CWH8 gene is now shown to complement the defects in growth and protein N-glycosylation, and to correct the accumulation of Dol-P-P in the cwh8Delta yeast mutant.	Nitrogen	4-5	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	102-106
20641832-9	2004	(6) has identified a modified peptide, (N(alpha)His)Ac-(Arg-N-CH3)-Arg-Pro-(dimethyl-Tyr)-(tertary-Leu)-Leu (NT-XIX), to be metabolically stable in plasma with good affinity for NTR1.	Nitrogen	60-62	neurotensin receptor 1	Mus musculus	178-182
12425645-2	2002	N(CH2CH2NR)3E (1, E = Sb, R = Me; 4, E = Bi, R = Me; 6, E = Sb, R = SiMe3; 8, E = Bi, R = SiMe3), by the reaction of E(NAlk2)3 (3, E = Sb, Alk = Et; 5, E = Bi, Alk = Me) with N(CH2CH2NMeH)3 (2) or N(CH2CH2NSiMe3H)3 (7) are reported.	Nitrogen	0-1	ALK receptor tyrosine kinase	Homo sapiens	120-123
12425645-2	2002	N(CH2CH2NR)3E (1, E = Sb, R = Me; 4, E = Bi, R = Me; 6, E = Sb, R = SiMe3; 8, E = Bi, R = SiMe3), by the reaction of E(NAlk2)3 (3, E = Sb, Alk = Et; 5, E = Bi, Alk = Me) with N(CH2CH2NMeH)3 (2) or N(CH2CH2NSiMe3H)3 (7) are reported.	Nitrogen	0-1	ALK receptor tyrosine kinase	Homo sapiens	139-142
12223479-5	2002	We investigated here the N-linked glycosylation of the beta4 subunit and its effect on the modulation of the hSlo alpha subunit.	Nitrogen	25-26	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	109-113
12223479-13	2002	Taken together, these data show that the pore-forming alpha subunit of the hSlo channel promotes N-linked glycosylation of its auxiliary beta4 subunit, and this in turn influences the modulation of the channel by the beta4 subunit.	Nitrogen	97-98	potassium calcium-activated channel subfamily M alpha 1	Homo sapiens	75-79
32038782-2	2008	The c-Jun N-terminal kinases (JNKs) have also been target for development of novel therapy in various diseases, since the roles of JNK signaling in pathological conditions were revealed in studies using jnk-deficient mice.	Nitrogen	10-11	mitogen-activated protein kinase 8	Mus musculus	30-33
32038782-2	2008	The c-Jun N-terminal kinases (JNKs) have also been target for development of novel therapy in various diseases, since the roles of JNK signaling in pathological conditions were revealed in studies using jnk-deficient mice.	Nitrogen	10-11	mitogen-activated protein kinase 8	Mus musculus	203-206
18407647-4	2008	Applicability of this method is demonstrated by various N-alkylated analogues of a cyclic CXCR4 receptor antagonist originally developed by Fujii et.	Nitrogen	56-57	C-X-C motif chemokine receptor 4	Homo sapiens	90-95
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	16-17	prolactin	Mus musculus	93-102
12421340-10	2002	After enzymatic N-deglycosylation of selected N-POMC isoforms, the stimulatory effect on the prolactin mRNA level was depressed (in case of the POMC1-95 isoforms) or totally abolished (in case of the POMC1-74 isoforms).	Nitrogen	46-47	prolactin	Mus musculus	93-102
19570529-0	2009	The influence of N-glycosylation on biochemical properties of Amy1, an alpha-amylase from the yeast Cryptococcus flavus.	Nitrogen	17-18	drug-responsive transcription factor PDR1	Saccharomyces cerevisiae S288C	62-66
18393501-4	2008	Collision-induced dissociation of the [OT - 3H + Cu](-) complex yielded exclusively C-terminal Cu(2+)-containing fragments (Cu(2+)fragment(3-)), suggesting that the Cu(2+) ligation site includes deprotonated C-terminal backbone amide nitrogen atoms and the N-terminal amino nitrogen atom in [OT - 3H + Cu](-).	Nitrogen	234-242	oxytocin/neurophysin I prepropeptide	Homo sapiens	39-41
18393501-4	2008	Collision-induced dissociation of the [OT - 3H + Cu](-) complex yielded exclusively C-terminal Cu(2+)-containing fragments (Cu(2+)fragment(3-)), suggesting that the Cu(2+) ligation site includes deprotonated C-terminal backbone amide nitrogen atoms and the N-terminal amino nitrogen atom in [OT - 3H + Cu](-).	Nitrogen	274-282	oxytocin/neurophysin I prepropeptide	Homo sapiens	39-41
18425328-6	2008	This form of beta1 integrin was only recognized by the 9EG7 anti-beta1 antibody and appeared devoid of other specific antibody epitopes (12G10, TS2/16 and mAb13 shown here to be N-glycosylation sensitive).	Nitrogen	178-179	integrin subunit beta 1	Homo sapiens	13-27
18305048-7	2008	The functionality of an engineered N glycosylation site in the cysteine-containing loop confirmed both its presence in the lumen and the transmembrane nature of nsp3.	Nitrogen	35-36	SH2 domain containing 3C	Homo sapiens	161-165
12270758-5	2002	In prazosin, the 4-amino group, 1-nitrogen atom and two methoxy groups of quinazoline ring possibly interact with the amino acids in TM3, TM5 and TM6 of alpha(1)-ARs.	Nitrogen	34-42	tropomyosin 3	Homo sapiens	133-136
12270758-5	2002	In prazosin, the 4-amino group, 1-nitrogen atom and two methoxy groups of quinazoline ring possibly interact with the amino acids in TM3, TM5 and TM6 of alpha(1)-ARs.	Nitrogen	34-42	tropomyosin 3	Homo sapiens	138-141
12270758-6	2002	In tamsulosin, amine group of ethanyl amine chain, methoxy group of benzene ring and sulfonamide nitrogen of benzene ring interacts in TM3, TM4 and TM5 of alpha(1)-ARs.	Nitrogen	97-105	tropomyosin 3	Homo sapiens	135-138
12270758-6	2002	In tamsulosin, amine group of ethanyl amine chain, methoxy group of benzene ring and sulfonamide nitrogen of benzene ring interacts in TM3, TM4 and TM5 of alpha(1)-ARs.	Nitrogen	97-105	tropomyosin 3	Homo sapiens	148-151
12270758-7	2002	In KMD-3213, amine of ethyl amine chain and indoline nitrogen of this compound possibly interact within TM3 and TM5 of alpha(1)-ARs.	Nitrogen	53-61	tropomyosin 3	Homo sapiens	104-107
12460116-11	2002	The following residues should be noted: lysine forming a Schiff base with the PLP aldehyde group, an adjacent histidine, and aspartic acid that establishes a link with nitrogen of the PLP pyridine ring.	Nitrogen	168-176	proteolipid protein 1	Homo sapiens	184-187
19570529-9	2009	Furthermore, the activity of the non-glycosylated enzyme was affected by Hg(2+) and Cu(2+) suggesting that N-glycosylation is involved in the folding of Amy1.	Nitrogen	107-108	drug-responsive transcription factor PDR1	Saccharomyces cerevisiae S288C	153-157
19574222-2	2009	The transcriptional activator Put3p allows yeast cells to utilize proline as a nitrogen source through expression of the PUT1 and PUT2 genes.	Nitrogen	79-87	1-pyrroline-5-carboxylate dehydrogenase	Saccharomyces cerevisiae S288C	130-134
18327899-0	2008	Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase.	Nitrogen	43-51	farnesyl diphosphate synthase	Homo sapiens	151-182
19595734-16	2009	Our report may provide clues regarding the nature of the biological amidase substrate(s) of Nit1 (another member of the Nit family), which is a well-established tumor suppressor protein), and emphasizes a) the crucial role of Nit2 in nitrogen and sulfur metabolism, and b) the possible link of Nit2 to cancer biology.	Nitrogen	234-242	nitrilase family member 2	Homo sapiens	226-230
18288598-4	2008	DENV-1 production was not detectable when full-length DENV-1 RNA, which has an N-glycosylation site Asn130-to-Ala (Asn130Ala) mutation in NS1, was transfected into mammalian and mosquito cells.	Nitrogen	2-3	influenza virus NS1A binding protein	Homo sapiens	138-141
18408871-2	2008	N-glycosylation inhibitors have a glycosylation-inhibiting effect, which is useful for the skin depigmentation that operates by interfering with the maturation of tyrosinase.	Nitrogen	0-1	tyrosinase	Homo sapiens	163-173
12228178-6	2002	Examples of such interindividual variation come from the study of very rare mutations of the human FMO3 gene that have been associated with deficient N-oxygenation of dietary trimethylamine.	Nitrogen	150-151	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	99-103
12476590-6	2002	In 17 patients whose compliance fluctuated between rank A and B, their rate of GFR decline(ml/min/month) was significantly faster(-2.40 +/- 2.59 vs 0.99 +/- 1.41, p &lt; 0.01), their rate of serum creatinine elevation(mg/dl/month) was significantly higher(0.90 +/- 0.79 vs -0.42 +/- 0.45, p &lt; 0.01) and their rate of serum urea nitrogen increase(mg/dl/month) was significantly larger(15.3 +/- 12.4 vs -10.0 +/- 12.9, p &lt; 0.01) during the period of rank B than rank A.	Nitrogen	331-339	Rap guanine nucleotide exchange factor 5	Homo sapiens	79-82
19595734-16	2009	Our report may provide clues regarding the nature of the biological amidase substrate(s) of Nit1 (another member of the Nit family), which is a well-established tumor suppressor protein), and emphasizes a) the crucial role of Nit2 in nitrogen and sulfur metabolism, and b) the possible link of Nit2 to cancer biology.	Nitrogen	234-242	nitrilase family member 2	Homo sapiens	294-298
19621239-4	2009	Several structural genes of flavonoid metabolism including CHS (chalcone synthase), FLS1 (flavonol synthase 1) and ANS (anthocyanidin synthase) were induced in response to nitrogen depletion in wild type as well as in the egl3 and gl3 mutants.	Nitrogen	172-180	Chalcone and stilbene synthase family protein	Arabidopsis thaliana	64-81
18160964-5	2008	In this group, higher KIM-1 staining predicted a better outcome with improved blood urea nitrogen (BUN), serum creatinine, and estimated glomerular filtration rate (eGFR) over an ensuing 18 months.	Nitrogen	89-97	hepatitis A virus cellular receptor 1	Homo sapiens	22-27
19636091-3	2009	We have shown that the Ir single-atom tip can be a good field ion emitter, capable of emitting a variety of gas ion beams, such as He+, H2+, N2+, and O2+, with high brightness and stability.	Nitrogen	141-144	TOR signaling pathway regulator	Homo sapiens	38-41
18164739-7	2008	Small alkyl residues at the amide nitrogen (hydrogen and methyl) lead to an inhibition of the enzyme Delta24-reductase, the N-ethyl and N-propyl derivatives show a dual action, inhibiting both Delta24-reductase and lathosterol oxidase.	Nitrogen	34-42	sterol-C5-desaturase	Homo sapiens	215-234
18164739-8	2008	Lathosterol-derived amides with larger substituents (butyl, isobutyl, tert-butyl, pentyl) at the amide nitrogen were found to be selective inhibitors of lathosterol oxidase.	Nitrogen	103-111	sterol-C5-desaturase	Homo sapiens	153-172
12351146-5	2002	For cancers in which N-acetylation is a detoxification step such as aromatic amine-related urinary bladder cancer, NAT2 slow acetylator phenotype is at higher risk.	Nitrogen	21-22	N-acetyltransferase 2	Homo sapiens	115-119
12351146-7	2002	In contrast, for cancers in which N-acetylation is negligible and O-acetylation is an activation step such as for heterocyclic amine-related colon cancer, NAT2 rapid acetylator phenotype is at higher risk.	Nitrogen	34-35	N-acetyltransferase 2	Homo sapiens	155-159
19645739-5	2009	We show that the CutA-AChE fusion proteins produced and secreted active, N-glycosylated molecules, while an AChE mutant lacking its secretory signal peptide did not produce any significant activity.	Nitrogen	73-74	acetylcholinesterase	Rattus norvegicus	22-26
12188604-3	2002	The N-bromination method (a PAM analytical technique based on N-bromination of amide groups and spectrophotometric determination of the formed starch-triiodide complex), which was originally developed for determining PAM in aqueous solutions, was modified to quantify substrate-borne PAM.	Nitrogen	4-5	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	28-31
12188604-3	2002	The N-bromination method (a PAM analytical technique based on N-bromination of amide groups and spectrophotometric determination of the formed starch-triiodide complex), which was originally developed for determining PAM in aqueous solutions, was modified to quantify substrate-borne PAM.	Nitrogen	4-5	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	217-220
12188604-3	2002	The N-bromination method (a PAM analytical technique based on N-bromination of amide groups and spectrophotometric determination of the formed starch-triiodide complex), which was originally developed for determining PAM in aqueous solutions, was modified to quantify substrate-borne PAM.	Nitrogen	4-5	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	217-220
12188604-3	2002	The N-bromination method (a PAM analytical technique based on N-bromination of amide groups and spectrophotometric determination of the formed starch-triiodide complex), which was originally developed for determining PAM in aqueous solutions, was modified to quantify substrate-borne PAM.	Nitrogen	62-63	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	28-31
12057649-5	2002	Optimization of the side chain at the central aniline nitrogen of 7-amidino-2-naphthoanilide has led to several potent and orally active FXa inhibitors.	Nitrogen	54-62	coagulation factor X	Homo sapiens	137-140
12067565-2	2002	They can be metabolised to reactive intermediates via N-hydroxylation catalysed by cytochrome P450 1A2, followed by conjugation of the resulting N-hydroxyl group by N-acetyltransferase (NAT) or sulfotransferase (SULT).	Nitrogen	54-55	bromodomain containing 2	Homo sapiens	165-184
12067565-2	2002	They can be metabolised to reactive intermediates via N-hydroxylation catalysed by cytochrome P450 1A2, followed by conjugation of the resulting N-hydroxyl group by N-acetyltransferase (NAT) or sulfotransferase (SULT).	Nitrogen	54-55	bromodomain containing 2	Homo sapiens	186-189
18077452-0	2008	Neuralized-like 1 (Neurl1) targeted to the plasma membrane by N-myristoylation regulates the Notch ligand Jagged1.	Nitrogen	0-1	neuralized E3 ubiquitin protein ligase 1	Homo sapiens	19-25
17998299-10	2008	Incubations with recombinant human uridine diphosphate glucuronosyltransferases (UGTs) indicated that the O-glucuronidation was catalyzed by UGT2B4 and UGT2B7, whereas the N-glucuronidation was catalyzed by UGT1A4.	Nitrogen	172-173	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	152-158
18004294-6	2008	Inactivation of IL-16 by antibody therapy or IL-16 deficiency prevented ischemia-reperfusion injury as shown by reduced levels of serum creatinine or blood urea nitrogen compared to control mice.	Nitrogen	161-169	interleukin 16	Mus musculus	16-21
18004294-6	2008	Inactivation of IL-16 by antibody therapy or IL-16 deficiency prevented ischemia-reperfusion injury as shown by reduced levels of serum creatinine or blood urea nitrogen compared to control mice.	Nitrogen	161-169	interleukin 16	Mus musculus	45-50
17929051-2	2008	Loss-of-function mutants of HY5 and HYH revealed that these genes are essential for induction of a key enzyme in nitrogen assimilation, nitrate reductase (EC 1.7.1.1).	Nitrogen	113-121	HY5-homolog	Arabidopsis thaliana	36-39
18167546-0	2008	The OSU1/QUA2/TSD2-encoded putative methyltransferase is a critical modulator of carbon and nitrogen nutrient balance response in Arabidopsis.	Nitrogen	92-100	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	4-8
12177810-4	2002	Nitrogen-containing bisphosphonates were shown to inhibit farnesyl diphosphate synthase, thus blocking the synthesis of higher isoprenoids.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	58-87
19556306-2	2009	The purposes of this study were to characterize the N-glycan of TLR4 and to investigate the roles of MD-2 in N-linked glycosylation and cell surface expression of TLR4.	Nitrogen	52-53	toll like receptor 4	Homo sapiens	64-68
12135569-0	2002	Expression and purification of the chloroplast putative nitrogen sensor, PII, of Arabidopsis thaliana.	Nitrogen	56-64	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	73-76
12135569-1	2002	The bacterial PII protein was discovered over 30 years ago and is known to be a key player in orchestrating the coordination of nitrogen metabolism with changes in carbon flux.	Nitrogen	128-136	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	14-17
12135569-2	2002	Bacterial PII is regulated by covalent modification and binding to effector molecules in response to the nitrogen/carbon status of the cell and appropriately coordinates the activity of glutamine synthetase and the transcription of a nitrogen sensitive regulon.	Nitrogen	105-113	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	10-13
12135569-2	2002	Bacterial PII is regulated by covalent modification and binding to effector molecules in response to the nitrogen/carbon status of the cell and appropriately coordinates the activity of glutamine synthetase and the transcription of a nitrogen sensitive regulon.	Nitrogen	234-242	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	10-13
18167546-0	2008	The OSU1/QUA2/TSD2-encoded putative methyltransferase is a critical modulator of carbon and nitrogen nutrient balance response in Arabidopsis.	Nitrogen	92-100	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	9-13
18167546-0	2008	The OSU1/QUA2/TSD2-encoded putative methyltransferase is a critical modulator of carbon and nitrogen nutrient balance response in Arabidopsis.	Nitrogen	92-100	S-adenosyl-L-methionine-dependent methyltransferases superfamily protein	Arabidopsis thaliana	14-18
18020422-2	2008	N-Methylation of Alloc-Cys(Trt)-OH and Boc-Cys(Trt)-OH gives the corresponding N-methylated derivatives in good yields and purities, which can be further derivatized in solution to obtain a myriad of S-protected derivatives.	Nitrogen	0-1	BOC cell adhesion associated, oncogene regulated	Homo sapiens	39-42
12135569-4	2002	The Arabidopsis thaliana putative nitrogen sensor protein, PII, was cloned and overexpressed with a C-terminal 6-histidine tag.	Nitrogen	34-42	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	59-62
19520434-10	2009	As CD5 has both N- and O-linked glycosylation, we hypothesised that differential binding of KEN-5 to T cells and B-cells may be explained by different glycan structures on the CD5 present on T compared to B cells.	Nitrogen	16-17	CD5 molecule	Homo sapiens	3-6
12222688-1	2002	N-acetyltransferase 2 (NAT2) catalyzes N-acetylation and O-acetylation of many drugs and environmental carcinogens.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	23-27
18020422-2	2008	N-Methylation of Alloc-Cys(Trt)-OH and Boc-Cys(Trt)-OH gives the corresponding N-methylated derivatives in good yields and purities, which can be further derivatized in solution to obtain a myriad of S-protected derivatives.	Nitrogen	79-80	BOC cell adhesion associated, oncogene regulated	Homo sapiens	39-42
19157012-3	2008	We have conducted structural studies on the redox regulation of PTP1B and have demonstrated that the oxidation of the catalytic cysteine results in the formation of a bond between the sulfur atom of the catalytic cysteine and the amide nitrogen of the neighboring serine.	Nitrogen	236-244	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	64-69
19372226-8	2009	Incubations with recombinant human UDP-glucuronosyltransferases (UGTs) and inhibition by the UGT1A4 and UGT1A1 substrates/inhibitors imipramine and bilirubin suggested that UGT1A4 is the major UGT isozyme catalyzing the N-glucuronidation of motesanib, with a minor contribution from UGT1A1.	Nitrogen	220-221	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	93-99
21200962-1	2007	The conformation of the N-H bond in the structure of the title compound, C(10)H(12)ClNO, is syn to the ortho methyl group, similar to that observed with respect to the meta methyl group in 2-chloro-N-(3-methyl-phen-yl)acetamide and the ortho-chloro group in 2-chloro-N-(2-chloro-phen-yl)acetamide.	Nitrogen	24-25	synemin	Homo sapiens	92-95
21200964-1	2007	The conformation of the N-H bond in the title compound, C(8)H(5)Cl(4)NO, is syn to the 2-chloro substituent and anti to the 5-chloro substituent in the aromatic ring.	Nitrogen	24-25	synemin	Homo sapiens	76-79
18055546-3	2007	A significant reduction in renal function loss (blood urea nitrogen) was observed after 24 hours of reperfusion of ischemically damaged kidneys in Mpo(-/-) mice compared with I/R WT controls (I/R Mpo(-/-) = 31.3 +/- 1.7 mmol/L versus I/R WT = 42.8 +/- 2.1 mmol/L, sham = 7.0 +/- 0.5 mmol/L; P = 0.003).	Nitrogen	59-67	myeloperoxidase	Mus musculus	147-150
17964420-2	2007	For this purpose we have assayed, in vitro and in vivo, the ability of CR-6 (3,4-dihydro-6-hydroxy-7-methoxy-2,2-dimethyl-1(2H)-benzopyran), an antioxidant able to scavenge nitrogen reactive species, to protect glutathione peroxidase (GPx) activity.	Nitrogen	173-181	growth arrest and DNA-damage-inducible 45 gamma	Mus musculus	71-75
12009951-4	2002	Receptor saturation studies, carried out on the GRP receptor-expressing PC-3 human prostate cancer cell line, revealed for [99mTc(CO)(3)-N(alpha)-histidinyl acetate]bombesin(7-14) K(d) values in the subnanomolar range.	Nitrogen	137-138	gastrin releasing peptide	Homo sapiens	48-51
12009951-4	2002	Receptor saturation studies, carried out on the GRP receptor-expressing PC-3 human prostate cancer cell line, revealed for [99mTc(CO)(3)-N(alpha)-histidinyl acetate]bombesin(7-14) K(d) values in the subnanomolar range.	Nitrogen	137-138	gastrin releasing peptide	Homo sapiens	165-173
12006544-9	2002	Because other studies suggest that PAO may be self-regulated in some tumors, differential expression of PAO may be the basis for selective toxicity of CHENSpm and other N-substituted polyamine analogues in certain cancers.	Nitrogen	154-155	polyamine oxidase	Homo sapiens	104-107
12012142-8	2002	CONCLUSION: The genetic defects of CYP2C19 have a significant effect on AT pharmacokinetics, and CYP2C19 plays an important role in N-demethylation of AT in vivo at a clinically therapeutic dose.	Nitrogen	2-3	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	35-42
12012142-8	2002	CONCLUSION: The genetic defects of CYP2C19 have a significant effect on AT pharmacokinetics, and CYP2C19 plays an important role in N-demethylation of AT in vivo at a clinically therapeutic dose.	Nitrogen	2-3	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	97-104
19372226-8	2009	Incubations with recombinant human UDP-glucuronosyltransferases (UGTs) and inhibition by the UGT1A4 and UGT1A1 substrates/inhibitors imipramine and bilirubin suggested that UGT1A4 is the major UGT isozyme catalyzing the N-glucuronidation of motesanib, with a minor contribution from UGT1A1.	Nitrogen	220-221	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	173-179
19486524-11	2009	In septic animals the phosphodiesterase 3 inhibitor, amrinone, preserved the tissue cAMP level, renal structural changes, and attenuated the increased blood urea nitrogen, creatinine, and iNOS expression in the kidney.	Nitrogen	162-170	phosphodiesterase 4D, cAMP-specific-like 1	Rattus norvegicus	22-41
11961028-5	2002	When cells were treated with the N-glycosylation inhibitor, tunicamycin, the molecular weight of nephrin was decreased to a single immunoband of 150 kD, indicating that the shift in the electrophoretic migration of nephrin is due to N-linked carbohydrate moieties.	Nitrogen	233-234	NPHS1 adhesion molecule, nephrin	Homo sapiens	215-222
11961028-7	2002	It was concluded that N-glycosylation of nephrin is crucial for its proper folding and thereby plasma membrane localization; therefore, inhibition of this process might be an important factor in the onset of pathogenesis of some acquired glomerular diseases.	Nitrogen	22-23	NPHS1 adhesion molecule, nephrin	Homo sapiens	41-48
12052141-6	2002	Certain mutations of the human FMO3 gene have been associated with abnormal N-oxygenation of trimethylamine.	Nitrogen	76-77	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	31-35
11948665-5	2002	One-hour exposure to N+Glu- led to a transient inhibition ( approximately 50%) of NPY production manifesting within 24 hr and recovering by 5 days thereafter, a 2-hr exposure to N+Glu- led to a sustained inhibition (50-75%) manifesting 1-5 days thereafter, and a 4-hr exposure to N+Glu- led to a total irreversible suppression of BDNF-induced production of NPY manifesting within 24 hr and lasting 8 days after re-supply of oxygen and glucose.	Nitrogen	21-22	brain-derived neurotrophic factor	Rattus norvegicus	330-334
11948665-5	2002	One-hour exposure to N+Glu- led to a transient inhibition ( approximately 50%) of NPY production manifesting within 24 hr and recovering by 5 days thereafter, a 2-hr exposure to N+Glu- led to a sustained inhibition (50-75%) manifesting 1-5 days thereafter, and a 4-hr exposure to N+Glu- led to a total irreversible suppression of BDNF-induced production of NPY manifesting within 24 hr and lasting 8 days after re-supply of oxygen and glucose.	Nitrogen	21-23	brain-derived neurotrophic factor	Rattus norvegicus	330-334
17976382-0	2007	Endoplasmic reticulum association and N-linked glycosylation of the human Nrf3 transcription factor.	Nitrogen	38-39	NFE2 like bZIP transcription factor 3	Homo sapiens	74-78
17914850-6	2007	The results of XRD, FTIR, and XPS spectra indicated that nitrogen was really doped into the anatase TiO2 shell and confirmed that most nitrogen dopants might be present in the chemical environments of N-Ti-O and Ti-N-O.	Nitrogen	57-65	mex-3 RNA binding family member D	Homo sapiens	212-218
19261610-5	2009	Removal of the N-glycosylation sites on the I-like domain of the beta1 subunit (i.e. the Delta4-6 mutant) decreased both the level of expression and heterodimeric formation, resulting in inhibition of cell spreading.	Nitrogen	15-16	delta like canonical Notch ligand 4	Homo sapiens	95-97
17604887-2	2007	The integrated perspective needed to quantify the net effect of N on greenhouse-gas balance is being addressed by the NitroEurope Integrated Project (NEU).	Nitrogen	64-65	neuralized E3 ubiquitin protein ligase 1	Homo sapiens	150-153
11952786-5	2002	A major portion of intact approximately 46-kDa Ac45 was found to be N-linked glycosylated to approximately 62 kDa and a minor fraction to approximately 64 kDa.	Nitrogen	68-69	ATPase H+ transporting accessory protein 1	Homo sapiens	47-51
11952786-10	2002	Tunicamycin inhibited N-linked glycosylation of Ac45 and interfered with the cleavage process, suggesting that Ac45 needs proper folding for the cleavage to occur.	Nitrogen	22-23	ATPase H+ transporting accessory protein 1	Homo sapiens	48-52
11952786-10	2002	Tunicamycin inhibited N-linked glycosylation of Ac45 and interfered with the cleavage process, suggesting that Ac45 needs proper folding for the cleavage to occur.	Nitrogen	22-23	ATPase H+ transporting accessory protein 1	Homo sapiens	111-115
19405983-2	2009	Denbinobin-induced cell apoptosis was attenuated by an ASK1 dominant-negative mutant (ASK1DN), two antioxidants (N-acetyl-L-cysteine (NAC) and glutathione (GSH)), a c-Jun N-terminal kinase (JNK) inhibitor (SP600125), and an activator protein-1 (AP-1) inhibitor (curcumin).	Nitrogen	91-92	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	55-59
11975741-9	2002	The results suggest that bacterial signals related to the bacterial ability to fix nitrogen, might be responsible for the regulation of HRGP expression in root nodules.	Nitrogen	83-91	histidine rich glycoprotein	Homo sapiens	136-140
17479278-2	2007	Because of a potential involvement of N-acetylation in the detoxication of reactive trichloroethylene metabolite(s) to N-acetyl-cysteine derivatives, polymorphisms of the NAT2 gene may also be relevant.	Nitrogen	38-39	N-acetyltransferase 2	Homo sapiens	171-175
17881533-8	2007	Thus, N-acylation is critical for correct compartmentalization of transducin and controls the rate of its deactivation.	Nitrogen	6-7	guanine nucleotide binding protein, alpha transducing 1	Mus musculus	66-76
11890767-0	2002	An experimental test of C-N bond twisting in the TICT state: syn-anti photoisomerization in 2-(N-methyl-N-isopropylamino)-5-cyanopyridine.	Nitrogen	26-27	synemin	Homo sapiens	61-64
19273591-4	2009	This could explain the observed decrease in both the basal and rapamycin-induced expression of several genes subjected to nitrogen catabolite repression (GAT1, MEP1, and GLN1) and stress response element (STRE)-driven promoters.	Nitrogen	122-130	glutamate--ammonia ligase	Saccharomyces cerevisiae S288C	170-174
11866606-5	2002	This hypothesis is reinforced by quantitative examination of the binding of N-methylated derivatives of 2-imidazolidone, which shows that N,N"-dimethylation decreases the affinity of Mg(15-crown-5)(Otf)2 for the ligand by 2 orders of magnitude.	Nitrogen	76-77	POU class 2 homeobox 2	Homo sapiens	198-203
17562328-2	2007	Key steps of the synthesis are the introduction of nitrogen functionalities at C-3 and C-6 and the olefin cross metathesis of allyl glycoside 16.	Nitrogen	51-59	complement C3	Homo sapiens	79-90
19275130-9	2009	These observations provide support for the carbocationic intermediate in the C(1)-N(2) scission process.	Nitrogen	82-84	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	77-81
17729221-0	2007	Hydrolyzed fumonisins HFB1 and HFB2 are acylated in vitro and in vivo by ceramide synthase to form cytotoxic N-acyl-metabolites.	Nitrogen	109-110	basic leucine zipper and W2 domains 2	Rattus norvegicus	31-35
17729221-3	2007	This study characterized the conversion of HFB1 and HFB2 by ceramide synthase to their respective N-acylated metabolites using rat liver microsomes and palmitoyl-CoA or nervonoyl-CoA as cosubstrates, and examined animals that had been dosed with hydrolyzed fumonisins to ascertain if acylation occurs in vivo.	Nitrogen	98-99	basic leucine zipper and W2 domains 2	Rattus norvegicus	52-56
11874570-0	2002	An EDS1 orthologue is required for N-mediated resistance against tobacco mosaic virus.	Nitrogen	35-36	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	3-7
19271954-6	2009	We show that, similar to Pto, Fen requires N-myristoylation and kinase activity for signaling and interacts with the N-terminal domain of Prf.	Nitrogen	43-44	serine/threonine protein kinase Pto	Solanum lycopersicum	25-28
11915349-0	2002	[N-glycosylation of sphingosine 1-phosphate receptor, Edg-1, and its role on receptor internalization through membrane microdomain].	Nitrogen	1-2	sphingosine-1-phosphate receptor 1	Homo sapiens	20-59
11856344-9	2002	CAP-18[106 -142], an antimicrobial cathelicidin peptide of rabbits, resembled SMAP-29 in that it contained N- and C-terminal LPS-binding domains, had an EC50 of 2.5 microm, and bound LPS with positive cooperativity.	Nitrogen	107-108	antimicrobial protein CAP18	Oryctolagus cuniculus	0-6
17588944-0	2007	The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue.	Nitrogen	95-96	peptidylprolyl isomerase B	Homo sapiens	57-70
17588944-4	2007	In addition to the involvement of 2-O,6-O, and N-sulfate groups, we also demonstrated that binding of CyPB was dependent on the presence of N-unsubstituted glucosamine residues (GlcNH2), which have been reported to be precursors for sulfation by 3-O-sulfotransferases-3 (3-OST-3).	Nitrogen	47-48	peptidylprolyl isomerase B	Homo sapiens	102-106
19231866-2	2009	The (2)BPNO(*) radical is connected to the PDI with the nitroxide and imide nitrogen atoms either para (1) or meta (3) to one another, as well as through a second intervening p-phenylene spacer (2).	Nitrogen	76-84	peptidyl arginine deiminase 1	Homo sapiens	43-46
17655217-4	2007	Syn orientation for the base and South (S) conformers for the sugar dominate at this temperature: syn/anti = 61.6%:38.4% and S/N = 74.5%:25.5%.	Nitrogen	127-128	synemin	Homo sapiens	0-3
18980942-2	2009	In this study we investigated whether the endosomal soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) proteins syntaxin 7 and syntaxin 8 are modified with palmitate.	Nitrogen	60-61	syntaxin 7	Homo sapiens	140-150
17433262-6	2007	The voriconazole 4-hydroxylation to N-oxidation metabolic ratios in liver microsomes from the wild-type CYP2C19*1/*1 individuals (0.07) were lower than those observed in other genotypes (0.20-0.27) at a substrate concentration of 25 microM based on the reported clinical plasma level.	Nitrogen	36-37	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	104-111
11786923-5	2002	Mouse Wnt14b was found to encode a 359-amino-acid WNT family protein with the N-terminal signal peptide, an N-linked glycosylation site, and 24 conserved cysteine residues.	Nitrogen	51-52	wingless-type MMTV integration site family, member 9B	Mus musculus	6-12
11785983-1	2002	We and others have recently shown that the major molecular target of nitrogen-containing bisphosphonate drugs is farnesyl diphosphate synthase, an enzyme in the mevalonate pathway.	Nitrogen	69-77	farnesyl diphosphate synthase	Homo sapiens	113-142
19054348-5	2009	When nitrogen was re-supplied, transcripts for main regulators of the pathway, PAP1/GL3 and PAP2/MYB12, fell to less than 1 and 0.1% of initial values, respectively, during 24 h in the 15-30 degrees C temperature range.	Nitrogen	5-13	regenerating family member 3 alpha	Homo sapiens	79-83
11860154-1	2002	Nociceptin (N/OFQ) is a novel heptadecapeptide with an amino acid sequence similar to that of endogenous opioid peptide dynorphin A. Dynorphin have been reported to increase the secretion of atrial natriuretic peptide (ANP) via selective activation of kappa-opioid receptor in cultured atrial cardiocytes.	Nitrogen	0-1	natriuretic peptide A	Rattus norvegicus	219-222
11860154-2	2002	The present study was designed to investigate the direct effect of N/OFQ on the ANP secretion in cultured neonatal rat cardiac myocytes via N/OFQ receptor (NOP) activation.	Nitrogen	67-68	natriuretic peptide A	Rattus norvegicus	80-83
11860154-11	2002	Therefore, these results suggest that N/OFQ causes an increase in ANP secretion in cultured neonatal cardiac myocytes by decreasing cAMP through its binding sites.	Nitrogen	38-39	natriuretic peptide A	Rattus norvegicus	66-69
17407817-2	2007	SAR was explored, suggesting that optimal binding with the receptor was achieved when the biphenylmethyl group and the linker were substituted on the same nitrogen of the urea moiety.	Nitrogen	155-163	sarcosine dehydrogenase	Homo sapiens	0-3
17382298-7	2007	On the contrary, PDBu, an activator of PKC, augmented N/OFQ-evoked responses.	Nitrogen	54-55	protein kinase C, gamma	Rattus norvegicus	39-42
18603331-0	2009	The influence of an ethylene spacer on the 5-HT(1A) and 5-HT(2A) receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones.	Nitrogen	128-129	5-hydroxytryptamine receptor 1A	Homo sapiens	43-50
11754575-4	2002	Examination of the SAR in this series has defined the size and chirality of the alpha-substituent, optimized the acyl substituent on the lactam nitrogen, and defined the steric constraint of this functionality.	Nitrogen	144-152	sarcosine dehydrogenase	Homo sapiens	19-22
11754575-5	2002	The SAR of the functionality on the pyrrolidine nitrogen of the trans-lactam has been investigated, and this has led to the discovery of potent serine protease inhibitors that are highly selective for the viral enzyme over the mammalian enzymes elastase, thrombin, and acetylcholine esterase.	Nitrogen	48-56	sarcosine dehydrogenase	Homo sapiens	4-7
19048287-8	2009	These data suggest that cytokinins regulate communication between reproductive and vegetative organs, and that GDH3 is one target of the cytokinin-mediated regulation of nitrogen metabolism.	Nitrogen	170-178	glutamate dehydrogenase 3	Arabidopsis thaliana	111-115
11788132-4	2002	A marked increase in c-Fos positive cells was induced after 2 h of breathing a gas mixture with elevated CO(2) (5% CO(2), 21% O(2) and 74% N(2), or 1 h following breathing of 12% CO(2,) 21% O(2,) and 67% N(2)).	Nitrogen	139-140	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	21-26
11788132-4	2002	A marked increase in c-Fos positive cells was induced after 2 h of breathing a gas mixture with elevated CO(2) (5% CO(2), 21% O(2) and 74% N(2), or 1 h following breathing of 12% CO(2,) 21% O(2,) and 67% N(2)).	Nitrogen	204-205	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	21-26
11796116-6	2002	The 3.0 A resolution structure of the XDH-alloxanthine complex shows direct coordination of alloxanthine to the molybdenum via a nitrogen atom.	Nitrogen	129-137	xanthine dehydrogenase	Bos taurus	38-41
11817366-3	2002	In accord with previous results obtained by electron-diffraction analysis, this single conformer possesses C1 symmetry in which the SF2 group is oriented syn with respect to the N-S single bond.	Nitrogen	178-179	serine and arginine rich splicing factor 1	Homo sapiens	132-135
11817366-3	2002	In accord with previous results obtained by electron-diffraction analysis, this single conformer possesses C1 symmetry in which the SF2 group is oriented syn with respect to the N-S single bond.	Nitrogen	178-179	synemin	Homo sapiens	154-157
17274762-6	2007	StIPMK also restores the amino acid profiles of mutant yeast to wild-type, and does so with ornithine or arginine as the sole nitrogen sources.	Nitrogen	126-134	inositol polyphosphate multikinase	Solanum tuberosum	0-6
17241121-8	2007	We show that GCPIII lacks dipeptidylpeptidase IV-like activity, its activity is dependent on N-glycosylation, and it is effectively inhibited by several known inhibitors of GCPII.	Nitrogen	93-94	folate hydrolase 1B (pseudogene)	Homo sapiens	13-19
17388537-4	2007	The minimum electron density in an intralayer Si-N bond was a little lower than that in an interlayer bond, which would be responsible for the inequality between elastic constants, C33 &gt; C11.	Nitrogen	49-50	CD82 molecule	Homo sapiens	181-184
17388537-4	2007	The minimum electron density in an intralayer Si-N bond was a little lower than that in an interlayer bond, which would be responsible for the inequality between elastic constants, C33 &gt; C11.	Nitrogen	49-50	aldo-keto reductase family 1 member C4	Homo sapiens	190-193
11577071-8	2001	Inhibition of CPS 1 by long-chain fatty acyl-CoAs could reduce amino acid degradation and urea secretion, thereby contributing to nitrogen sparing during starvation.	Nitrogen	130-138	carbamoyl-phosphate synthase 1	Rattus norvegicus	14-19
18790819-8	2009	Recent studies have shown that seipin, an endoplasmic reticulum (ER)-resident membrane protein, is an N-glycosylated protein that is proteolytically cleaved into N- and C-terminal fragments and is polyubiquitinated.	Nitrogen	102-103	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	31-37
11595744-8	2001	This difference in TBP binding could imply differential recruitment of target proteins by ER alpha-N and ER beta-N.	Nitrogen	99-100	TATA-box binding protein	Homo sapiens	19-22
17291013-5	2007	The novel metabolites include extensive N-acetylated AaC conjugates, multiple N-glucuronides, and at least one additional site of aromatic ring hydroxylation.	Nitrogen	40-41	glycine-N-acyltransferase	Homo sapiens	53-56
17263732-6	2007	By comparing protein O-fucosyltransferase 1 sequences available in databases, we observed that mammalian protein O-fucosyltransferase 1 enzymes possess two putative N-glycosylation sites, and that only the first is conserved among bilaterians.	Nitrogen	165-166	protein O-fucosyltransferase 1	Homo sapiens	13-43
17263732-6	2007	By comparing protein O-fucosyltransferase 1 sequences available in databases, we observed that mammalian protein O-fucosyltransferase 1 enzymes possess two putative N-glycosylation sites, and that only the first is conserved among bilaterians.	Nitrogen	165-166	protein O-fucosyltransferase 1	Homo sapiens	105-135
18790819-8	2009	Recent studies have shown that seipin, an endoplasmic reticulum (ER)-resident membrane protein, is an N-glycosylated protein that is proteolytically cleaved into N- and C-terminal fragments and is polyubiquitinated.	Nitrogen	162-163	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	31-37
17179073-11	2007	Mutants lacking Tsc1 or Tsc2 are highly sensitive to rapamycin under poor nitrogen conditions, suggesting that the function of Tor1 under such conditions is sensitive to rapamycin.	Nitrogen	74-82	TSC complex subunit 2	Homo sapiens	24-28
11717182-3	2001	For example, abnormal N-oxygenation of trimethylamine has been shown to segregate with mutations of human FMO3.	Nitrogen	22-23	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	106-110
18790819-9	2009	Interestingly, the N88S and S90L mutations are in the N-glycosylation motif, and these mutations enhance ubiquitination and degradation of seipin by the ubiquitin-proteasome system (UPS).	Nitrogen	19-20	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	139-145
19353850-5	2009	In both aerosols and rainwater over the East China Sea, the concentrations of urea nitrogen were higher in spring than those in winter.	Nitrogen	83-91	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	51-54
11570886-5	2001	The shape of the absorption spectrum of Co(2+)-DPP III was very similar to that of Co(2+)-carboxypeptidase A or Co(2+)-thermolysin, in which the Co(2+) is bound to two histidyl nitrogens, a water molecule, and a glutamate residue.	Nitrogen	177-186	dipeptidylpeptidase 3	Rattus norvegicus	47-54
11570886-8	2001	The five lines of the superfine structure in the perpendicular region of the EPR spectrum in Cu(2+)-DPP III suggest that nitrogen atoms should coordinate to the cupric ion in Cu(2+)-DPP III.	Nitrogen	121-129	dipeptidylpeptidase 3	Rattus norvegicus	100-107
17212372-0	2007	Identification of N-linked glycosylation sites in human nephrin using mass spectrometry.	Nitrogen	18-19	NPHS1 adhesion molecule, nephrin	Homo sapiens	56-63
17212372-2	2007	Ten potential asparagine (N)-linked glycosylation sites have been predicted within the ectodomain of nephrin.	Nitrogen	25-28	NPHS1 adhesion molecule, nephrin	Homo sapiens	101-108
17212372-9	2007	Thus, nine of ten potential glycosylation sites in nephrin were experimentally proven to be modified by N-linked glycosylation.	Nitrogen	104-105	NPHS1 adhesion molecule, nephrin	Homo sapiens	51-58
11570886-8	2001	The five lines of the superfine structure in the perpendicular region of the EPR spectrum in Cu(2+)-DPP III suggest that nitrogen atoms should coordinate to the cupric ion in Cu(2+)-DPP III.	Nitrogen	121-129	dipeptidylpeptidase 3	Rattus norvegicus	182-189
18979233-7	2009	Some upregulated genes, such as Slc38a5 and Slc1a7 encoding glutamine transporters, may be parts of the total body adaptation to alleviate negative nitrogen balance.	Nitrogen	148-156	solute carrier family 38, member 5	Rattus norvegicus	32-39
11544325-0	2001	N-linked glycosylations at Asn(26) and Asn(114) of human MD-2 are required for toll-like receptor 4-mediated activation of NF-kappaB by lipopolysaccharide.	Nitrogen	0-1	lymphocyte antigen 96	Homo sapiens	57-61
11544325-7	2001	These observations demonstrate that hMD-2 undergoes N-linked glycosylation at Asn(26) and Asn(114), and that these glycosylations are crucial for TLR4-mediated signal transduction of LPS.	Nitrogen	52-53	lymphocyte antigen 96	Homo sapiens	36-41
17260978-3	2007	Product yields for the reaction of cis-2-butene with Cl in N2 at 700 Torr are meso-2,3-dichlorobutane (47%), DL-2,3-dichlorobutane (18%), 3-chloro-1-butene (13%), cis-1-chloro-2-butene (13%), trans-1-chloro-2-butene (2%), and trans-2-butene (8%).	Nitrogen	59-61	suppressor of cytokine signaling 2	Homo sapiens	35-40
17235138-6	2007	High-SCC milk presented significantly higher total protein and nonprotein nitrogen and lower true protein and casein concentrations than did low-SCC milk, indicating an increased whey protein content and a higher level of proteolysis.	Nitrogen	74-82	SCC	Bos taurus	5-8
17198416-7	2007	Theoretical calculations confirm that NCl2- can readily lose Cl- and that N2Cl2 also possesses a low barrier toward loss of N2 to give chlorine atoms and, thus, can account for the formation of NCl3.	Nitrogen	74-76	calpain 5	Homo sapiens	194-198
11549275-1	2001	Histamine N-methyltransferase (HNMT) catalyzes the N-methylation of histamine in mammals.	Nitrogen	10-11	histamine N-methyltransferase	Homo sapiens	31-35
11516162-3	2001	A mouse DAF CCP1-4 mutant protein in which its two potential N-glycosylation sites were deleted by changing Asn(187) and Asn(262) to Gln was also produced.	Nitrogen	61-62	CD55 molecule, decay accelerating factor for complement	Mus musculus	8-11
19413687-6	2009	pyd2 and pyd3 mutants were unable to catabolize [2-(14)C]-uracil or to grow on uracil as the sole nitrogen source.	Nitrogen	98-106	beta-ureidopropionase	Arabidopsis thaliana	9-13
11514736-6	2001	Furthermore, we demonstrated that all three putative N-linked glycosylation sites of NS1 are utilized and that the Asn(207) glycosylation site contains a mannose-rich glycan.	Nitrogen	53-54	influenza virus NS1A binding protein	Homo sapiens	85-88
17653303-3	2007	Site-directed mutagenesis was employed to generate mutant azurocidin variants lacking individual N-glycosylation sites.	Nitrogen	97-98	azurocidin 1	Homo sapiens	58-68
17653303-5	2007	We also demonstrate that N-linked glycosylation contributes to azurocidin stability by protecting it from proteolysis.	Nitrogen	25-26	azurocidin 1	Homo sapiens	63-73
19073648-5	2009	Concentration-dependent analysis of (15)N-labeled ammonium influx into roots of AtAMT1;4-transformed plants allowed characterization of AtAMT1;4 as a high-affinity transporter with a K(m) of 17 microM.	Nitrogen	40-41	ammonium transporter 1;4	Arabidopsis thaliana	80-88
17269229-2	2007	This study uses a radio frequency (rf) discharge to consider the effect of added CH4 and CO to simulated NO/N2/O2/H2O mixtures on the elevation of NO conversion and the reduction of NO into N2.	Nitrogen	190-192	immunoglobulin kappa variable 1D-39	Homo sapiens	111-117
16963142-2	2007	One of these, the protein product of HCMV open reading frame (ORF) UL33, has been identified in HCMV-infected cells and virus particles and shown to be heat-aggregatable and N-glycosylated.	Nitrogen	174-175	envelope glycoprotein UL33	Human betaherpesvirus 5	67-71
11384996-0	2001	Association of a novel PDZ domain-containing peripheral Golgi protein with the Q-SNARE (Q-soluble N-ethylmaleimide-sensitive fusion protein (NSF) attachment protein receptor) protein syntaxin 6.	Nitrogen	82-83	syntaxin 6	Homo sapiens	183-193
19073648-9	2009	These results suggest that AtAMT1;4 mediates ammonium uptake across the plasma membrane of pollen to contribute to nitrogen nutrition of pollen via ammonium uptake or retrieval.	Nitrogen	115-123	ammonium transporter 1;4	Arabidopsis thaliana	27-35
11477110-0	2001	The yeast SEC20 gene is required for N- and O-glycosylation in the Golgi.	Nitrogen	37-38	Sec20p	Saccharomyces cerevisiae S288C	10-15
19123496-3	2008	The ionic-neutral curve crossing involving the lowest two (1)Sigma(+) states of LiF molecule is studied using the IVO-MCQDPT method, while its single-root version (IVO-MRMPPT) is employed to study the ground state PEC for isomerization of butadiene and to model the bond dissociation of N(2) molecule.	Nitrogen	287-291	LIF interleukin 6 family cytokine	Homo sapiens	80-83
11477110-4	2001	During the characterization of N-glycosylation-defective mutants (ngd) previously isolated by this laboratory, it was found that ngd20 is allelic to sec20.	Nitrogen	31-32	Sec20p	Saccharomyces cerevisiae S288C	149-154
11477110-6	2001	We show now that SEC20 is also required for N- and O-glycosylation in the Golgi but not in the ER, in a cargo-specific manner, and that the glycosylation defect does not correlate with the secretory defect.	Nitrogen	44-45	Sec20p	Saccharomyces cerevisiae S288C	17-22
11356835-7	2001	Our data suggest that nitrogen starvation regulates translation of GCN4 by a novel mechanism that involves the four upstream open reading frames but that still acts independently of eukaryotic initiation factor-2 alpha phosphorylation by Gcn2p.	Nitrogen	22-30	serine/threonine-protein kinase GCN2	Saccharomyces cerevisiae S288C	238-243
16905323-5	2006	These results indicate that the dopamine transporter can tolerate some variability in proximity of the benzhydryl ether to the basic nitrogen atom of the tropane without loss in potency.	Nitrogen	133-141	solute carrier family 6 member 3	Homo sapiens	32-52
17050773-11	2006	Quantitative analysis of N-linked glycosylation of IgA heavy chains showed significant differences in glycan composition between mIgA and pIgA, including the presence of oligomannose exclusively on pIgA.	Nitrogen	25-26	immunoglobulin heavy constant alpha	Mus musculus	51-54
17050773-11	2006	Quantitative analysis of N-linked glycosylation of IgA heavy chains showed significant differences in glycan composition between mIgA and pIgA, including the presence of oligomannose exclusively on pIgA.	Nitrogen	25-26	immunoglobulin heavy constant alpha	Mus musculus	129-133
19032039-2	2008	The presence of a lipophilic dodecyl appendage at imidazolium nitrogen in 3 successfully allows the selective determination of AcO(-) ions in protic (CHCl(3)-MeOH, 1:1) solvent.	Nitrogen	62-70	kallikrein related peptidase 15	Homo sapiens	127-130
17115712-7	2006	In contrast, the FXa-catalyzed hydrolysis of N-alpha-Z-D-Arg-Gly-Arg-pNA.2HCl (S-2765) and H-D-Ile-L-Pro-L-Arg-pNA.HCl (S-2288) is most consistent with two-proton bridges forming at the transition state between Ser195 OgammaH and His57 N(epsilon)2 and His57 Ndelta1 and Asp102 COObeta- at the active site, with transition-state fractionation factors of phi1 = phi2 = 0.57 +/- 0.07 and phiS = 0.78 +/- 0.16 for solvent rearrangement for S-2765 and phi1 = phi2 = 0.674 +/- 0.001 for S-2288 under enzyme saturation with the substrate at pH 8.40 and 25.0 +/- 0.1 degrees C. The rate-determining step(s) in these reactions is most likely the cleavage of the C-N bond and departure of the leaving group.	Nitrogen	45-46	coagulation factor X	Homo sapiens	17-20
11412044-3	2001	Potential N-linked glycosylation sites on the lumenal domains of mouse gp75/TRP-1/Tyrp1 and human tyrosinase were eliminated by site-directed mutagenesis (Asn to Gln substitutions).	Nitrogen	10-11	tyrosinase-related protein 1	Mus musculus	76-81
11412044-3	2001	Potential N-linked glycosylation sites on the lumenal domains of mouse gp75/TRP-1/Tyrp1 and human tyrosinase were eliminated by site-directed mutagenesis (Asn to Gln substitutions).	Nitrogen	10-11	tyrosinase-related protein 1	Mus musculus	82-87
11412044-3	2001	Potential N-linked glycosylation sites on the lumenal domains of mouse gp75/TRP-1/Tyrp1 and human tyrosinase were eliminated by site-directed mutagenesis (Asn to Gln substitutions).	Nitrogen	10-11	tyrosinase	Homo sapiens	98-108
11473699-0	2001	The nitrogen-induced recovery of alpha-zein gene expression in in vitro cultured opaque2 maize endosperms depends on the genetic background.	Nitrogen	4-12	regulatory protein opaque-2	Zea mays	81-88
17083230-7	2006	The Ca(II) ion has a coordination number of eight, lying in the plane of the tetradentate PDA, with Ca-N bonds averaging 2.55 A and Ca-O bonds to the two acetate groups of PDA averaging 2.45 A.	Nitrogen	103-104	carbonic anhydrase 2	Homo sapiens	4-10
19013524-1	2008	When nitrogen is abundant, prokaryotic and eukaryotic oxygen-producing photosynthetic organisms store nitrogen as arginine, by relieving feedback inhibition of the arginine biosynthesis controlling enzyme, N-acetylglutamate kinase (NAGK).	Nitrogen	5-13	N-acetylglucosamine kinase	Homo sapiens	206-230
16959765-0	2006	N-glycosylation of the beta-propeller domain of the integrin alpha5 subunit is essential for alpha5beta1 heterodimerization, expression on the cell surface, and its biological function.	Nitrogen	0-1	integrin subunit alpha 5	Bos taurus	52-67
17062705-5	2006	RESULTS: Nitrogen-containing bisphosphonates act intracellularly by inhibiting farnesyl diphosphate synthase, an enzyme of the mevalonate pathway, thereby preventing prenylation of small GTPase signaling proteins required for normal cellular function.	Nitrogen	9-17	farnesyl diphosphate synthase	Homo sapiens	79-108
16828555-9	2006	This indicates that the side-chain oxygen or nitrogen atom at position 148 of 15-PGDH plays an important role in anchoring C-15 hydroxyl group of PGE2 through hydrogen bonding for catalytic reaction.	Nitrogen	45-53	carbonyl reductase 1	Homo sapiens	78-85
16919392-1	2006	Secreted phospholipase B enzymes (PLB1) with high levels of N-linked glycosylation are proven fungal virulence determinants.	Nitrogen	60-61	lysophospholipase	Saccharomyces cerevisiae S288C	34-38
16905358-5	2006	One gene, Nar1.2, was strongly carbon-regulated independently of Nit2; two genes, Nar1.1 and Nar1.6, were regulated by nitrogen and Nit2; and the other genes, Nar1.3, Nar1.4, and Nar1.5 were independent of Nit2 and responded to nitrogen or carbon treatments in a transient and not easily understandable way.	Nitrogen	119-127	NAR1.1	Chlamydomonas reinhardtii	82-88
16864574-0	2006	Transduction of the nitrogen signal activating Gln3-mediated transcription is independent of Npr1 kinase and Rsp5-Bul1/2 ubiquitin ligase in Saccharomyces cerevisiae.	Nitrogen	20-28	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	93-97
16864574-4	2006	The Npr1 kinase controls the activity of various permeases including transporters for nitrogen sources that stimulate NCR such as the Mep ammonium transport systems.	Nitrogen	86-94	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	4-8
16864574-6	2006	The derepression of Gln3-activated genes in ammonium-grown npr1 cells results from the reduced uptake of the nitrogen-repressing compound because NCR could be restored in npr1 cells by repairing ammonium-uptake defects through different means.	Nitrogen	109-117	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	59-63
16864574-6	2006	The derepression of Gln3-activated genes in ammonium-grown npr1 cells results from the reduced uptake of the nitrogen-repressing compound because NCR could be restored in npr1 cells by repairing ammonium-uptake defects through different means.	Nitrogen	109-117	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	171-175
16754785-0	2006	Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels.	Nitrogen	15-16	potassium voltage-gated channel subfamily B member 2	Homo sapiens	148-153
16754785-0	2006	Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels.	Nitrogen	15-16	potassium voltage-gated channel subfamily B member 1	Homo sapiens	158-163
16859706-4	2006	PNGase treatment and mutational studies determined that TPST1 bears N-linked glycosyl residues exclusively at position Asn60 and Asn262.	Nitrogen	1-2	tyrosylprotein sulfotransferase 1	Homo sapiens	56-61
16884302-5	2006	While retention of the maleimide ring and pendant 4-phenyl group is necessary for potency, replacement of the carbazole nitrogen by oxygen is well tolerated and results in improved Wee1 selectivity against the related checkpoint kinase Chk1.	Nitrogen	120-128	WEE1 G2 checkpoint kinase	Homo sapiens	181-185
16884302-6	2006	Wee1 potency and selectivity are also enhanced by the incorporation of lipophilic functionality at the 2"-position of the 4-phenyl ring, and Wee1 selectivity against Chk1 is favored by C3-C5 alkyl substitution of the carbazole nitrogen.	Nitrogen	227-235	WEE1 G2 checkpoint kinase	Homo sapiens	0-4
16884302-6	2006	Wee1 potency and selectivity are also enhanced by the incorporation of lipophilic functionality at the 2"-position of the 4-phenyl ring, and Wee1 selectivity against Chk1 is favored by C3-C5 alkyl substitution of the carbazole nitrogen.	Nitrogen	227-235	WEE1 G2 checkpoint kinase	Homo sapiens	141-145
16750364-0	2006	The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist.	Nitrogen	47-55	5-hydroxytryptamine receptor 2C	Rattus norvegicus	82-88
16750364-2	2006	We describe the design and synthesis of a novel tricyclic single-nitrogen scaffold that was used to produce 5-HT2C agonists.	Nitrogen	65-73	5-hydroxytryptamine receptor 2C	Rattus norvegicus	108-114
16880720-6	2006	Here we report the asymmetric construction of highly substituted chiral nitrogen heterocycles via intramolecular conjugate addition of chiral enolates generated from N-Boc-N-alkylylamino acid derivatives.	Nitrogen	72-80	BOC cell adhesion associated, oncogene regulated	Homo sapiens	168-171
16685272-0	2006	Dermcidin expression in hepatic cells improves survival without N-glycosylation, but requires asparagine residues.	Nitrogen	64-65	dermcidin	Homo sapiens	0-9
16685272-1	2006	Proteolysis-inducing factor, a cachexia-inducing tumour product, is an N-glycosylated peptide with homology to the unglycosylated neuronal survival peptide Y-P30 and a predicted product of the dermcidin gene, a pro-survival oncogene in breast cancer.	Nitrogen	71-72	dermcidin	Homo sapiens	193-202
16631105-7	2006	The Arg272, Lys210, and Gly271 peptide bond nitrogen system, present in the corresponding space of rabbit PGI, creates an area of positive MEP, stabilizing cis-enolate intermediate and attracting its structural mimics, such as 5PA.	Nitrogen	44-52	glucose-6-phosphate isomerase	Oryctolagus cuniculus	106-109
16704256-3	2006	H-abstraction reactions from thiols and triethylsilane show that the spin density is predominantly localized on both nitrogens.	Nitrogen	117-126	spindlin 1	Homo sapiens	69-73
16407266-8	2006	Strikingly, the deletion of TOR1, which regulates cellular response to changes in nitrogen availability, from the wild type strain abolished the CCR-induced amino acid uptake.	Nitrogen	82-90	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	28-32
16476981-0	2006	CCR5 use by human immunodeficiency virus type 1 is associated closely with the gp120 V3 loop N-linked glycosylation site.	Nitrogen	93-94	C-C motif chemokine receptor 5	Homo sapiens	0-4
16722157-6	2006	On each of its heavy chain, IgA1 has at least two N-glycosidically bound oligosaccharides and 3 to 5 O-linked side-chains.	Nitrogen	50-51	immunoglobulin heavy constant alpha 1	Homo sapiens	28-32
16231018-7	2006	In a further study, the anorectic effect of peripherally administered PYY(3-36) is attenuated in unhandled rats (88 +/- 4.2% saline control, P = ns) or rats exposed to environmental enrichment (103.3 +/- 9.7% saline control, P = ns), but not in animals that were handled extensively prior to the study (80.1 +/- 7.3% saline control, P &lt; 0.05).	Nitrogen	145-147	peptide YY	Rattus norvegicus	70-73
16231018-7	2006	In a further study, the anorectic effect of peripherally administered PYY(3-36) is attenuated in unhandled rats (88 +/- 4.2% saline control, P = ns) or rats exposed to environmental enrichment (103.3 +/- 9.7% saline control, P = ns), but not in animals that were handled extensively prior to the study (80.1 +/- 7.3% saline control, P &lt; 0.05).	Nitrogen	229-231	peptide YY	Rattus norvegicus	70-73
16390150-2	2006	A step in the PIE curve versus photon energy, obtained with N(2) as the carrier gas, supports the conclusion of very effective cooling of C(3) to its linear (1)Sigma(g)(+) ground state.	Nitrogen	60-64	complement C3	Homo sapiens	138-142
16352304-9	2006	These data suggest that N/OFQ differentially activates ERK, p38, and JNK MAPK to contribute to potentiated prostaglandin vasoconstriction after fluid percussion brain injury.	Nitrogen	24-25	mitogen-activated protein kinase 8	Sus scrofa	69-72
16399498-2	2006	In a recent issue of Cell, show that altering N-glycosylation of the GLUT2 glucose transporter prevents its anchoring and retention at the cell surface; this impairs glucose uptake and insulin secretion.	Nitrogen	46-47	solute carrier family 2 member 2	Homo sapiens	69-74
16802848-10	2006	Clearance is hepatic via N-oxidation by the hepatic cytochrome P450 (CYP) isoenzymes, CYP2C19, CYP2C9 and CYP3A4.	Nitrogen	25-26	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	86-93
18228487-6	2006	Root peroxisomes in the nodules of legumes, for example, sequester enzymes such as allantoinase and uricase, which contribute to nitrogen metabolism in these tissues.	Nitrogen	129-137	urate oxidase (pseudogene)	Homo sapiens	100-107
16216433-4	2006	Recently, farnesyl pyrophosphate synthase has been shown as a molecular target of nitrogen-containing bisphosphonates, and inhibition of post-translational prenylation of small molecular weight G proteins is likely involved in their anti-resorptive activity on osteoclasts.	Nitrogen	82-90	farnesyl diphosphate synthase	Homo sapiens	10-41
16216433-6	2006	These observations let us to speculate that minodronate, a newly developed nitrogen-containing bisphosphonate, might be a promising remedy for treating patients with diabetic retinopathy by inhibiting the AGE-RAGE signaling pathways through suppression of ROS generation via inhibition of Rac prenylation.	Nitrogen	75-83	long intergenic non-protein coding RNA 914	Homo sapiens	209-213
11403614-1	2001	The vapor of (chlorocarbonyl)sulfenyl bromide, ClC(O)SBr, was isolated in solid Ar, Kr, N(2), and Ar doped with 5% CO at 15 K, and the matrix was subsequently irradiated with broad-band UV--visible light (200 &lt; or = lambda &lt; or = 800 nm), the changes being followed by reference to the IR spectrum of the matrix.	Nitrogen	88-92	Charcot-Leyden crystal galectin	Homo sapiens	47-50
11340165-0	2001	Xbp1-mediated repression of CLB gene expression contributes to the modifications of yeast cell morphology and cell cycle seen during nitrogen-limited growth.	Nitrogen	133-141	Xbp1p	Saccharomyces cerevisiae S288C	0-4
11340165-6	2001	We found that Clb1, Clb2, and Clb5 cyclin levels are reduced in nitrogen-limited chemostat cultures compared to levels in rich-medium cultures, whereas the Xbp1 transcriptional repressor is highly induced under these conditions.	Nitrogen	64-72	B-type cyclin CLB2	Saccharomyces cerevisiae S288C	20-24
11340165-7	2001	Furthermore, the deletion of XBP1 prevents the drop in Clb2 levels and inhibits cellular elongation in nitrogen-limited chemostat cultures as well as inhibiting pseudohyphal growth on nitrogen-limited agar media.	Nitrogen	103-111	Xbp1p	Saccharomyces cerevisiae S288C	29-33
11340165-7	2001	Furthermore, the deletion of XBP1 prevents the drop in Clb2 levels and inhibits cellular elongation in nitrogen-limited chemostat cultures as well as inhibiting pseudohyphal growth on nitrogen-limited agar media.	Nitrogen	184-192	Xbp1p	Saccharomyces cerevisiae S288C	29-33
11340165-8	2001	Deletion of the CLB2 gene restores an elongated morphology and filamentation to the xbp1Delta mutant in response to nitrogen limitation.	Nitrogen	116-124	B-type cyclin CLB2	Saccharomyces cerevisiae S288C	16-20
11340165-9	2001	Transcriptional activation of the XBP1 gene and the subsequent repression of CLB gene expression are thus key responses of yeast cells to nitrogen limitation.	Nitrogen	138-146	Xbp1p	Saccharomyces cerevisiae S288C	34-38
11352928-3	2001	We found that overexpression of Bul1p or Bul2p, two nonessential components of the Rsp5p E3-ubiquitin ligase complex, causes Gap1p to be sorted to the vacuole regardless of nitrogen source.	Nitrogen	173-181	ubiquitin-ubiquitin ligase BUL1	Saccharomyces cerevisiae S288C	32-37
11352928-3	2001	We found that overexpression of Bul1p or Bul2p, two nonessential components of the Rsp5p E3-ubiquitin ligase complex, causes Gap1p to be sorted to the vacuole regardless of nitrogen source.	Nitrogen	173-181	ubiquitin-ubiquitin ligase BUL2	Saccharomyces cerevisiae S288C	41-46
11327890-0	2001	Modeling the active site chemistry of liver alcohol dehydrogenase: mononuclear zinc methanol and N,N-dimethylformamide complexes of a nitrogen/sulfur ligand possessing an internal hydrogen bond donor.	Nitrogen	134-142	aldo-keto reductase family 1 member A1	Homo sapiens	44-65
11372865-1	2001	The effect of oxygen-nitrogen atmosphere (N2 + 10%O2, N2 + 1%O2 and 99.999% N2) on the formation of PCB, PCDD and PCDF by the de novo synthetic reactions in the system consisting of extracted fly ash (from municipal waste incinerators--MWI), activated carbon, CuCl2 x 2H2O and NaCl at 340 degrees C was studied.	Nitrogen	21-29	Pyruvate carboxylase	Drosophila melanogaster	100-103
11372865-1	2001	The effect of oxygen-nitrogen atmosphere (N2 + 10%O2, N2 + 1%O2 and 99.999% N2) on the formation of PCB, PCDD and PCDF by the de novo synthetic reactions in the system consisting of extracted fly ash (from municipal waste incinerators--MWI), activated carbon, CuCl2 x 2H2O and NaCl at 340 degrees C was studied.	Nitrogen	42-44	Pyruvate carboxylase	Drosophila melanogaster	100-103
11372865-1	2001	The effect of oxygen-nitrogen atmosphere (N2 + 10%O2, N2 + 1%O2 and 99.999% N2) on the formation of PCB, PCDD and PCDF by the de novo synthetic reactions in the system consisting of extracted fly ash (from municipal waste incinerators--MWI), activated carbon, CuCl2 x 2H2O and NaCl at 340 degrees C was studied.	Nitrogen	54-56	Pyruvate carboxylase	Drosophila melanogaster	100-103
11401696-1	2001	In Saccharomyces cerevisiae, the ability to use proline as a nitrogen source requires the Put3p transcriptional regulator, which turns on the expression of the proline utilization genes, PUT1 and PUT2, in the presence of the inducer proline and in the absence of preferred nitrogen sources.	Nitrogen	61-69	Put3p	Saccharomyces cerevisiae S288C	90-95
11401696-1	2001	In Saccharomyces cerevisiae, the ability to use proline as a nitrogen source requires the Put3p transcriptional regulator, which turns on the expression of the proline utilization genes, PUT1 and PUT2, in the presence of the inducer proline and in the absence of preferred nitrogen sources.	Nitrogen	273-281	Put3p	Saccharomyces cerevisiae S288C	90-95
11401708-6	2001	Unexpectedly, the moderate (approximately threefold) overexpression of Pph22 that we obtained increased basal trehalase activity and rendered this activity unresponsive to the addition of glucose or a nitrogen source.	Nitrogen	201-209	phosphoprotein phosphatase 2A catalytic subunit PPH22	Saccharomyces cerevisiae S288C	71-76
11278567-0	2001	N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization.	Nitrogen	0-1	C-C motif chemokine receptor 5	Homo sapiens	95-99
11278567-0	2001	N-linked glycosylation of the HIV type-1 gp120 envelope glycoprotein as a major determinant of CCR5 and CXCR4 coreceptor utilization.	Nitrogen	0-1	C-X-C motif chemokine receptor 4	Homo sapiens	104-109
11278567-4	2001	The V1V2 region and its N-linked glycosylation degree were shown to confer CXCR4 usage and provide the virus with rapid replication kinetics.	Nitrogen	24-25	C-X-C motif chemokine receptor 4	Homo sapiens	75-80
11278567-6	2001	The loss of this V3 N-linked glycosylation site was also linked with the broadening of the coreceptor repertoire to incorporate CCR3.	Nitrogen	20-21	C-C motif chemokine receptor 3	Homo sapiens	128-132
11300787-2	2001	We found previously that treatment of oxidized cytochrome b(561) with diethyl pyrocarbonate caused specific N-carbethoxylation of three fully conserved residues (His88, His161, and Lys85) located at the extravesicular side.	Nitrogen	108-109	cytochrome b	Bos taurus	47-59
16354708-4	2006	Previously, we have shown that proficient and error-free replication through the gamma-HOPdG (gamma-hydroxy-1,N2-propano-2"-deoxyguanosine) adduct, which is formed from the reaction of acrolein with the N2 of guanine, is mediated by the sequential action of human Poliota and Polkappa, in which Poliota incorporates the nucleotide opposite the lesion site and Polkappa carries out the subsequent extension reaction.	Nitrogen	110-112	DNA polymerase mu	Homo sapiens	264-271
16354708-4	2006	Previously, we have shown that proficient and error-free replication through the gamma-HOPdG (gamma-hydroxy-1,N2-propano-2"-deoxyguanosine) adduct, which is formed from the reaction of acrolein with the N2 of guanine, is mediated by the sequential action of human Poliota and Polkappa, in which Poliota incorporates the nucleotide opposite the lesion site and Polkappa carries out the subsequent extension reaction.	Nitrogen	110-112	DNA polymerase lambda	Homo sapiens	276-284
16354708-4	2006	Previously, we have shown that proficient and error-free replication through the gamma-HOPdG (gamma-hydroxy-1,N2-propano-2"-deoxyguanosine) adduct, which is formed from the reaction of acrolein with the N2 of guanine, is mediated by the sequential action of human Poliota and Polkappa, in which Poliota incorporates the nucleotide opposite the lesion site and Polkappa carries out the subsequent extension reaction.	Nitrogen	110-112	DNA polymerase mu	Homo sapiens	295-302
16605017-1	2006	To reduce MBR O&amp;M costs, a new MBR process that conducts efficient simultaneous biological nitrogen and phosphorus removal (BNR) was developed.	Nitrogen	95-103	translocator protein	Homo sapiens	35-38
16253991-1	2005	Retrograde (RTG) signaling senses mitochondrial dysfunction and initiates readjustments of carbohydrate and nitrogen metabolism through nuclear accumulation of the heterodimeric transcription factors, Rtg1/3p.	Nitrogen	108-116	Rtg1p	Saccharomyces cerevisiae S288C	201-205
19013524-1	2008	When nitrogen is abundant, prokaryotic and eukaryotic oxygen-producing photosynthetic organisms store nitrogen as arginine, by relieving feedback inhibition of the arginine biosynthesis controlling enzyme, N-acetylglutamate kinase (NAGK).	Nitrogen	5-13	N-acetylglucosamine kinase	Homo sapiens	232-236
16342937-14	2005	Last, nearly all potential N-glycosylation sites are occupied in the rat zonae glycoproteins (three of three for ZP1, six or seven of seven for ZP2, and four or five of six for ZP3).	Nitrogen	27-28	zona pellucida glycoprotein 2	Rattus norvegicus	144-147
16342937-14	2005	Last, nearly all potential N-glycosylation sites are occupied in the rat zonae glycoproteins (three of three for ZP1, six or seven of seven for ZP2, and four or five of six for ZP3).	Nitrogen	27-28	zona pellucida glycoprotein 3	Rattus norvegicus	177-180
19013524-1	2008	When nitrogen is abundant, prokaryotic and eukaryotic oxygen-producing photosynthetic organisms store nitrogen as arginine, by relieving feedback inhibition of the arginine biosynthesis controlling enzyme, N-acetylglutamate kinase (NAGK).	Nitrogen	102-110	N-acetylglucosamine kinase	Homo sapiens	206-230
19013524-1	2008	When nitrogen is abundant, prokaryotic and eukaryotic oxygen-producing photosynthetic organisms store nitrogen as arginine, by relieving feedback inhibition of the arginine biosynthesis controlling enzyme, N-acetylglutamate kinase (NAGK).	Nitrogen	102-110	N-acetylglucosamine kinase	Homo sapiens	232-236
19013524-2	2008	The signalling protein PII, an ancient and widely distributed nitrogen/carbon/ADP/ATP sensor, mediates feedback inhibition relief of NAGK by binding to this enzyme.	Nitrogen	62-70	N-acetylglucosamine kinase	Homo sapiens	133-137
18955570-5	2008	The other, a point mutation in the paternal X chromosome allele encoding a G174R substitution, altered an N-linked glycosylation site within the cytokine binding domain and glycosylation of GM-CSF-Ralpha, severely reducing GM-CSF binding, receptor signaling, and GM-CSF-dependent functions in primary myeloid cells.	Nitrogen	106-107	colony stimulating factor 2	Homo sapiens	223-229
16266689-3	2005	The peptide backbone of CD52, consisting of only 12 aminoacids, is generally considered no more than a scaffold for post-translational modifications, such as GPI-anchor and especially N-glycosylation which occur at the third asparagine.	Nitrogen	184-185	CD52 molecule	Homo sapiens	24-28
16202999-9	2005	Finally, trafficking of Mid1-GFP to the plasma membrane was dependent on the N-glycosylation of Mid1 and the transporter protein Sec12.	Nitrogen	77-78	Mid1p	Saccharomyces cerevisiae S288C	24-28
11323770-2	2001	MR-spectroscopy (MRS) records protons from tissue chemicals other than water, intrinsic phosphorus containing metabolites, sodium, potassium, carbon, nitrogen, and fluorine.	Nitrogen	150-158	sterile alpha motif domain containing 11	Mus musculus	17-20
11373305-7	2001	Evidence is provided that PEPCK may play a role in pH regulation in tissues active in the metabolism of nitrogen.	Nitrogen	104-112	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	26-31
16202999-9	2005	Finally, trafficking of Mid1-GFP to the plasma membrane was dependent on the N-glycosylation of Mid1 and the transporter protein Sec12.	Nitrogen	77-78	Mid1p	Saccharomyces cerevisiae S288C	96-100
18939788-4	2008	The monomers adsorb on the exterior surface of the vesicles, where their spontaneous self-aggregation to (CdS)n clusters occurs on the hour and day time scale.	Nitrogen	6-7	CDP-diacylglycerol synthase 1	Homo sapiens	106-109
16202999-9	2005	Finally, trafficking of Mid1-GFP to the plasma membrane was dependent on the N-glycosylation of Mid1 and the transporter protein Sec12.	Nitrogen	77-78	Sar family guanine nucleotide exchange factor SEC12	Saccharomyces cerevisiae S288C	129-134
11337936-5	2001	Reductions in catalytic activity for the N-acetylation of a sulfonamide drug (sulfamethazine) and an aromatic amine carcinogen (2-aminofluorene) were observed for NAT2 variants possessing G191A (R64Q), T341C (I114T), A434C (E145P), G590A (R197Q), A845C (K282T) or G857A (G286T).	Nitrogen	41-42	N-acetyltransferase 2	Homo sapiens	163-167
11283348-5	2001	Interestingly, overexpression of LPE1 from &gt;10 gene copies resulted in transformants with pleiotropically reduced growth rates on various nitrogen sources and the absolute inability to transport purines.	Nitrogen	141-149	nucleobase-ascorbate transporter LPE1	Zea mays	33-37
18462383-5	2008	Moreover, we demonstrate that Ure2p/Gln3p proteins mainly control the bioconversion of volatile thiols by the transcriptional regulation of the IRC7 gene through the general mechanism of nitrogen catabolic repression.	Nitrogen	187-195	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	36-41
11380948-0	2001	Evidence for a novel polymorphism affecting both N-linked glycosylation and ligand binding of the IgG receptor IIIB (CD16).	Nitrogen	49-50	Fc gamma receptor IIIa	Homo sapiens	117-121
16185646-6	2005	In addition, NO-based modifications of proteins and peptides on nonsulfur groups (e.g., carbon, oxygen, nitrogen) are detected on DAF gels.	Nitrogen	104-112	CD55 molecule (Cromer blood group)	Homo sapiens	130-133
16387704-0	2005	Cloning and expression of a functionally active truncated N-glycosylated KSHV ORF4/KCP/kaposica in the methylotrophic yeast Pichia pastoris.	Nitrogen	58-59	KCP	Human gammaherpesvirus 8	78-82
18837550-3	2008	X-ray and variable temperature NMR studies link the unique stability of MIDA boronates to a kinetic inaccessibility of the potentially reactive boron p-orbital and/or nitrogen lone pair.	Nitrogen	167-175	NADH:ubiquinone oxidoreductase complex assembly factor 7	Homo sapiens	72-76
16387704-0	2005	Cloning and expression of a functionally active truncated N-glycosylated KSHV ORF4/KCP/kaposica in the methylotrophic yeast Pichia pastoris.	Nitrogen	58-59	KCP	Human gammaherpesvirus 8	83-86
16240455-8	2005	In addition, BUD8 that encodes the distal landmark in yeast-form bipolar budding is required for nitrogen starvation-induced but not HU-induced filamentous growth.	Nitrogen	97-105	Bud8p	Saccharomyces cerevisiae S288C	13-17
11159233-5	2001	The number of Fos-like immunoreactivity positive cells by ketamine IV at a dose of 5 mg/kg under 70% N(2)O (128 +/- 12 cells per 0.5 mm(2)) was significantly more than those under 30% (15 +/- 2 cells per 0.5 mm(2)) and 70% xenon (2 +/- 1 cells per 0.5 mm(2)).	Nitrogen	101-102	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	14-17
11170313-4	2001	The aim of this study was to investigate the role of N-acetylation of PAP to APAP in PAP-induced toxicity.	Nitrogen	53-54	poly (A) polymerase alpha	Mus musculus	70-73
11170313-4	2001	The aim of this study was to investigate the role of N-acetylation of PAP to APAP in PAP-induced toxicity.	Nitrogen	53-54	poly (A) polymerase alpha	Mus musculus	78-81
11170313-13	2001	The results suggest the roles of GSH and N-acetylation of PAP to APAP in PAP-induced hepatotoxicity.	Nitrogen	41-42	poly (A) polymerase alpha	Mus musculus	58-61
11170313-13	2001	The results suggest the roles of GSH and N-acetylation of PAP to APAP in PAP-induced hepatotoxicity.	Nitrogen	41-42	poly (A) polymerase alpha	Mus musculus	66-69
11118203-9	2000	In response to nitrogen starvation, asymmetric localization of Bud9p is averted, favouring Bud8p-mediated cell division at the distal pole.	Nitrogen	15-23	Bud8p	Saccharomyces cerevisiae S288C	91-96
16113996-6	2005	These results suggested that the reduction of the substrates by 3alpha-HSD is affected by the nitrogen atom in the aromatic ring.	Nitrogen	94-102	aldo-keto reductase family 1, member C14	Rattus norvegicus	64-74
18421563-1	2008	A nitrogen-related signal transduction pathway, consisting of the three phosphotransfer proteins EI(Ntr), NPr, and IIA(Ntr), was discovered recently to regulate the uptake of K(+) in Escherichia coli.	Nitrogen	2-10	colicin Ia immunity protein	Escherichia coli	115-118
16160185-1	2005	Using PCR mutagenesis to disrupt the NXT/S N-linked glycosylation motif of the Env protein, we created 27 mutants lacking 1 to 5 of 14 N-linked glycosylation sites within regions of gp120 lying outside of variable loops 1 to 4 within simian immunodeficiency virus strain 239 (SIV239).	Nitrogen	37-38	envelope protein	Simian immunodeficiency virus	79-82
16160185-1	2005	Using PCR mutagenesis to disrupt the NXT/S N-linked glycosylation motif of the Env protein, we created 27 mutants lacking 1 to 5 of 14 N-linked glycosylation sites within regions of gp120 lying outside of variable loops 1 to 4 within simian immunodeficiency virus strain 239 (SIV239).	Nitrogen	43-44	envelope protein	Simian immunodeficiency virus	79-82
11169414-2	2000	Detailed analysis of human ICOS presented here shows that it is a 55-60-kDa homodimer with differently N-glycosylated subunits of 27 and 29 kDa.	Nitrogen	103-104	inducible T cell costimulator	Homo sapiens	27-31
18691229-9	2008	Beriplex P/N showed the greatest capacity for thrombin inhibition, a reflection of the observed high levels of the coagulation inhibitors protein C, protein S, protein Z, and small amounts of antithrombin III and heparin in this product.	Nitrogen	11-12	serpin family C member 1	Homo sapiens	192-208
11092862-12	2000	threefold induction of ICL2 mRNA levels and of 2-methylisocitrate lyase activity in cell extracts relative to cultures grown with ammonia as the nitrogen source.	Nitrogen	145-153	methylisocitrate lyase ICL2	Saccharomyces cerevisiae S288C	23-27
11118085-6	2000	RESULTS: There were significant improvements in serum creatinine and blood urea nitrogen at 24 hr in the NA-NP group when compared with the IC group (P&lt;0.05).	Nitrogen	80-88	N-acetylneuraminic acid phosphatase	Rattus norvegicus	105-110
16051304-5	2005	Finally, we demonstrate that LSECtin is N-linked glycosylated and that glycosylation is required for cell surface expression.	Nitrogen	40-41	C-type lectin domain family 4 member G	Homo sapiens	29-36
16054434-2	2005	The 1,10-diazachrysene (1,10-DAC) and 4,10-DAC, nitrogen-substituted analogs of chrysene, were shown to exhibit mutagenicity in Salmonella typhimurium TA100 in the presence of rat liver S9 and human liver microsomes in our previous report, although DACs could not be converted to a bay-region diol epoxide, the ultimate active form of chrysene, because of their nitrogen atoms.	Nitrogen	48-56	dachshund family transcription factor 1	Mus musculus	43-46
11076970-4	2000	Expression of these genes in media containing urea or ammonia as a sole nitrogen source requires the heterodimeric bZip transcription factors Rtg1 and Rtg3 and correlates with a redistribution of the Rtg1p/Rtg3 complex from a predominantly cytoplasmic to a predominantly nuclear location.	Nitrogen	72-80	Rtg1p	Saccharomyces cerevisiae S288C	142-146
11076970-4	2000	Expression of these genes in media containing urea or ammonia as a sole nitrogen source requires the heterodimeric bZip transcription factors Rtg1 and Rtg3 and correlates with a redistribution of the Rtg1p/Rtg3 complex from a predominantly cytoplasmic to a predominantly nuclear location.	Nitrogen	72-80	Rtg1p	Saccharomyces cerevisiae S288C	200-205
15931460-5	2005	Glycosidase analysis of cellular and secreted forms confirmed that Fpv060, Fpv061 and Fpv121 were N-glycosylated and that the most abundant, cellular form of Fpv061 had been glycosylated but remained Endo H-sensitive (retained in the endoplasmic reticulum or Golgi).	Nitrogen	98-99	CC chemokine gene family protein	Fowlpox virus	67-73
18753286-7	2008	In contrast, AtPTR1 plays a role in uptake of peptides by roots indicated by reduced nitrogen (N) levels and reduced growth of atptr1 mutants on medium with dipeptides as the sole N source.	Nitrogen	85-93	peptide transporter 1	Arabidopsis thaliana	13-19
16055315-6	2005	This C. albicans gene is located in chromosome R. STE13ca gene increases its levels of expression in conditions of nutritional stress (proline as nitrogen source) and during formation of the germinal tube, suggesting a basic biological function for the STE13ca in this yeast.	Nitrogen	146-154	Ste13p	Saccharomyces cerevisiae S288C	50-55
11050152-5	2000	Incubation of nicotine with cytochrome P450 2A6 and cofactors did indeed produce aminoketone, which was identified as its N-benzoyl derivative by GC-MS.	Nitrogen	122-123	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	28-47
18619416-2	2008	Both these transporters contain potential sites for N-glycosylation in their extracellular domains (Asn-138, Asn-144 [hSVCT1]; Asn-188, Asn-196 [hSVCT2]), however the role of N-glycosylation in transporter function is unexplored.	Nitrogen	52-53	solute carrier family 23 member 1	Homo sapiens	118-124
11032869-8	2000	These results demonstrate that the signal peptide is required for efficient cell surface expression and N-linked glycosylation of the PAC(1)R.	Nitrogen	104-105	adenylate cyclase activating polypeptide 1 receptor 1	Mus musculus	134-141
11147716-1	2000	Two complete series of N-protected oligopeptide esters to the pentamer level from 1-amino-cycloundecane-1-carboxylic acid (Ac11c), an alpha-amino acid conformationally constrained through a medium-ring C(i)alpha&lt;--&gt;C(i)alpha cyclization, and either the L-Ala or Aib residue, along with the N-protected Ac11c monomer and homo-dimer alkylamides, have been synthesized by solution methods and fully characterized.	Nitrogen	23-24	ANIB1	Homo sapiens	268-271
16105875-8	2005	Treatment of the two forms of beta1 with PGNase reduced their masses to approximately 90 kDa, suggesting that N-glycosylation was responsible for the mass differences.	Nitrogen	43-44	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	30-35
18619416-3	2008	On the basis of the result that tunicamycin decreased (14)C-ascorbic acid uptake in HepG2 cells, we systematically ablated all consensus N-glycosylation sites in hSVCT1 and hSVCT2 to resolve any effects on ascorbic acid uptake, transporter expression and targeting.	Nitrogen	137-138	solute carrier family 23 member 1	Homo sapiens	162-168
16107153-3	2005	In aldose reductase, Leu300 forms a hydrogen bond through its main-chain nitrogen atom with the exocyclic amide group of the inhibitor, which when replaced with a Pro in aldehyde reductase, cannot form a hydrogen bond, thus causing a loss in binding energy.	Nitrogen	73-81	aldo-keto reductase family 1 member A1	Homo sapiens	170-188
18619416-4	2008	We show that removal of individual N-glycosylation sites significantly impairs protein expression and consequently ascorbic acid uptake for hSVCT1 mutants (N138Q is retained intracellularly) and for hSVCT2 mutants (all of which reach the cell surface).	Nitrogen	35-36	solute carrier family 23 member 1	Homo sapiens	140-146
16076179-2	2005	Recent X-ray crystallographic studies revealed an unexpected chemical transformation underlying the redox regulation of protein tyrosine phosphatase 1B, in which oxidative inactivation of the enzyme yields an intrastrand protein cross-link between the catalytic cysteine residue and its neighboring amide nitrogen.	Nitrogen	305-313	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	120-151
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	CART prepropeptide	Rattus norvegicus	128-173
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	CART prepropeptide	Rattus norvegicus	175-179
15890775-4	2005	We hypothesized that N/OFQ may regulate hypothalamic neurons containing peptides involved in the control of food intake such as cocaine- and amphetamine-regulated transcript (CART), alphaMSH, neuropeptide Y (NPY), and agouti-related protein (AgRP).	Nitrogen	21-22	proopiomelanocortin	Rattus norvegicus	182-190
15890775-6	2005	Incubation of hypothalamic explants with N/OFQ (1, 10, 100 nM) resulted in significant changes in CART and AgRP release.	Nitrogen	41-42	CART prepropeptide	Rattus norvegicus	98-102
15822115-11	2005	Compared to PAG-1 the number of potential N-glycosylation sites is lower in PAG-17 (three sites) and higher in PAG-6 and -7 (five and six sites, respectively).	Nitrogen	42-43	pregnancy-associated glycoprotein 17	Bos taurus	76-82
11091438-0	2000	The First Stable Diazonium Ion on Solid Support-Investigations on Stability and Usage as Linker and Scavenger in Solid-Phase Organic Synthesis Nitrogen-Based Linkers, Part 8.	Nitrogen	143-151	poly(ADP-ribose) polymerase family member 14	Homo sapiens	167-173
11012666-6	2000	The full-length DPP8 cDNA codes for an 882-amino-acid protein that has about 27% identity and 51% similarity to DPPIV and FAP, but no transmembrane domain and no N-linked or O-linked glycosylation.	Nitrogen	23-24	dipeptidyl peptidase 8	Homo sapiens	16-20
10992007-1	2000	The amino-terminal ectodomain of human thyrotropin receptor (TSHR) contains six potential N-linked glycosylation sites (N-Xaa-S/T).	Nitrogen	90-91	thyroid stimulating hormone receptor	Homo sapiens	39-59
10992007-1	2000	The amino-terminal ectodomain of human thyrotropin receptor (TSHR) contains six potential N-linked glycosylation sites (N-Xaa-S/T).	Nitrogen	90-91	thyroid stimulating hormone receptor	Homo sapiens	61-65
18721458-0	2008	A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction.	Nitrogen	18-19	envelope polyprotein;hypothetical protein	Feline immunodeficiency virus	48-69
10995240-7	2000	CD spectroscopy indicates that N-218 MLN64 is largely alpha-helical and minimally affected by changes in ionic strength or the hydrophobic character of the solvent, although glycerol increases the beta-sheet content.	Nitrogen	31-32	StAR related lipid transfer domain containing 3	Homo sapiens	37-42
15892050-6	2005	Furthermore, DkkL1 was N-glycosylated in the testis, but it did not appear to be excreted, and the DkkL1 in mature sperm was no longer N-glycosylated, suggesting that additional post-translational modifications occurred during the final stages of spermatogenesis.	Nitrogen	23-24	dickkopf like acrosomal protein 1	Homo sapiens	13-18
16040659-3	2005	Using an Arabidopsis (Arabidopsis thaliana) atg7 mutant unable to ligate either tag, we previously showed that the ATG8/12 conjugation system is important for survival under nitrogen-limiting growth conditions.	Nitrogen	174-182	ThiF family protein	Arabidopsis thaliana	44-48
18721458-4	2008	In addition to a characteristic increase in charge in the V3 loop homologue of FIVFL4, we identified two mutations in potential sites for N-linked glycosylation in the region of FIV Env analogous to the V1-V2 region of HIV and SIV Env, T271I and N342Y.	Nitrogen	138-139	envelope polyprotein;hypothetical protein	Feline immunodeficiency virus	182-185
18721458-4	2008	In addition to a characteristic increase in charge in the V3 loop homologue of FIVFL4, we identified two mutations in potential sites for N-linked glycosylation in the region of FIV Env analogous to the V1-V2 region of HIV and SIV Env, T271I and N342Y.	Nitrogen	138-139	envelope polyprotein;hypothetical protein	Feline immunodeficiency virus	231-234
10987948-0	2000	Transformation of arylmethylamines into alpha-aminophosphonic acids via metalated phosphoramidates: rearrangement of partly configurationally stable N-phosphorylated alpha-aminocarbanions N-Benzyl phosphoramidate was protected at nitrogen with a TMS, p-toluenesulfonyl, Boc, lithium carboxylate, or diethoxyphosphinyl group and metalated with s-BuLi or LDA at -78 degrees C at the benzylic carbon.	Nitrogen	149-150	BOC cell adhesion associated, oncogene regulated	Homo sapiens	270-273
18534984-0	2008	Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog.	Nitrogen	56-57	sonic hedgehog signaling molecule	Homo sapiens	76-90
10989127-9	2000	A potential N-glycosylation site (site 1) with similar tripeptide patterns was observed at the same position in human plasma (HYAL1), human lysosomes (HYAL2) and in two newly reported hyaluronidases (HYAL4 and HYALP1).	Nitrogen	12-13	hyaluronidase 6, pseudogene	Homo sapiens	210-216
15984892-6	2005	The isotope effect is attributed to a lowered zero-point energy of a C-H bond adjacent to an amine nitrogen, arising from delocalization of either a syn or an anti lone pair, and with no detectable angle-independent inductive effect.	Nitrogen	99-107	synemin	Homo sapiens	149-152
18598060-12	2008	Their nucleophilic character at C-2 permits reactions with oxygen, nitrogen, and sulfur electrophiles that under high substrate stereocontrol generally lead to three-membered rings; ring opening under acid catalysis furnishes the corresponding glycosides, whichdepending on the electrophile Xare also employed for 2-deoxyglycoside synthesis.	Nitrogen	67-75	complement C2	Homo sapiens	32-35
15964819-5	2005	Tissue histology and other hematological parameters were normal, as was the majority of serum biochemistry, with the exception that blood urea nitrogen (BUN) levels were decreased in mice lacking SSB-2.	Nitrogen	143-151	splA/ryanodine receptor domain and SOCS box containing 2	Mus musculus	196-201
10970296-8	2000	Thus, whereas compounds having a diprotected nitrogen led to syn adducts, compounds having a monoprotected nitrogen gave rise to anti adducts.	Nitrogen	45-53	synemin	Homo sapiens	61-64
18514033-3	2008	ER alpha deficient NZM females, but not males, had significantly prolonged survival, reduced proteinuria, renal pathology scores and serum urea nitrogen levels compared to wildtype mice, despite higher serum anti-dsDNA levels.	Nitrogen	144-152	estrogen receptor 1 (alpha)	Mus musculus	0-8
10961890-9	2000	The antagonistic effect of heparin on hIL-10 activity was shown to be dependent on N-sulfation, inasmuch as de-N-sulfated heparin had little or no inhibitory effect on the IL-10- induced expression of CD16, whereas the effect of de-O-sulfated heparin was comparable to that of unmodified heparin.	Nitrogen	83-84	interleukin 10	Homo sapiens	38-44
10961890-9	2000	The antagonistic effect of heparin on hIL-10 activity was shown to be dependent on N-sulfation, inasmuch as de-N-sulfated heparin had little or no inhibitory effect on the IL-10- induced expression of CD16, whereas the effect of de-O-sulfated heparin was comparable to that of unmodified heparin.	Nitrogen	83-84	interleukin 10	Homo sapiens	39-44
10999748-6	2000	The incidence of the positive expression of MMP-9 in n(+)-IMGCs (67%) or ly(+)-IMGCs (86%) was significantly higher than that in n(-)-IMGCs (32%) or ly(-)-IMGCs (34%).	Nitrogen	53-57	matrix metallopeptidase 9	Homo sapiens	44-49
11465082-3	2000	Human FMO3 N-oxygenates primary, secondary and tertiary amines whereas human FMO1 is only highly efficient at N-oxygenating tertiary amines.	Nitrogen	11-12	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	6-10
15933030-4	2005	Transcript level analysis revealed that among the five thiamine-pyrophospate-dependent decarboxylases (PDC1, PDC5, PDC6, ARO10, and THI3), only ARO10 was transcriptionally up-regulated when phenylalanine, leucine, or methionine was used as a nitrogen source compared to growth on ammonia, proline, and asparagine.	Nitrogen	242-250	indolepyruvate decarboxylase 6	Saccharomyces cerevisiae S288C	115-119
15862605-6	2005	Therefore it seemed reasonable to study the potential of cytochrome b5, NADH-cytochrome b5 reductase and CYP2D to detoxify these N-hydroxylated metabolites by N-reduction.	Nitrogen	129-130	cytochrome b5 type A	Sus scrofa	57-70
15862605-6	2005	Therefore it seemed reasonable to study the potential of cytochrome b5, NADH-cytochrome b5 reductase and CYP2D to detoxify these N-hydroxylated metabolites by N-reduction.	Nitrogen	129-130	cytochrome b5 type A	Sus scrofa	77-90
15892579-4	2005	Coincubation of IPO and rabbit CYP4B1 with glutathione gave rise to multiple products due likely to the presence of both sulfur and nitrogen nucleophiles in the same trapping molecule.	Nitrogen	132-140	cytochrome P450 4B1	Oryctolagus cuniculus	31-37
18724742-6	2008	Instead, a single species of ant constituted approximately 35% of the annual diet (stomach contents analysis) and up to 90% of assimilated nitrogen (estimates from stable isotope analysis).	Nitrogen	139-147	solute carrier family 25 member 6	Homo sapiens	29-32
15683915-6	2005	In contrast to mammalian LECT2 protein, trout LECT2 protein reveals two potential N-glycosylation sites.	Nitrogen	82-83	leukocyte cell derived chemotaxin 2	Homo sapiens	46-51
10946229-4	2000	Crystal structures of AAG complexed to DNA suggest that the enzyme selects substrate bases through a combination of hydrogen bonding and the steric constraints of the active site, and that the enzyme activates a water molecule for an in-line backside attack of the N-glycosylic bond.	Nitrogen	40-41	N-methylpurine DNA glycosylase	Homo sapiens	22-25
10905408-4	2000	The nitrogen-diffusion-hardened Ti64 alloy had TiN and TiNO complexes at the immediate surface and sub-surface layers.	Nitrogen	4-12	mex-3 RNA binding family member D	Homo sapiens	55-59
15647342-7	2005	DNase I KO mice were also markedly protected against the toxic injury induced by a single injection of cisplatin (20 mg/kg), by both functional (blood urea nitrogen and serum creatinine) and histologic criteria (tubular necrosis and in situ DNA fragmentation assessed by the terminal deoxynucleotidyl transferase nick end-labeling).	Nitrogen	156-164	deoxyribonuclease I	Mus musculus	0-7
18585921-2	2008	Mutations in the N-glycosylation site of seipin are associated with the disease states and result in accumulation of unfolded protein in the endoplasmic reticulum (ER), leading to the unfolded protein response (UPR) and cell death, suggesting that these diseases are tightly associated with ER stress.	Nitrogen	17-18	BSCL2 lipid droplet biogenesis associated, seipin	Homo sapiens	41-47
15689404-5	2005	When pretreated with G-CSF or G-CSF + M-CSF, the mice showed longer survival and lower serum creatinine and blood urea nitrogen levels than mice that had been received injections of M-CSF or saline.	Nitrogen	119-127	colony stimulating factor 1 (macrophage)	Mus musculus	38-43
10901693-3	2000	Two UDP-glucuronosyltransferases (UGTs) present in human liver, UGT1A4 and UGT1A3, were previously shown to catalyze tertiary amine N-glucuronidation when expressed in HK293 cells.	Nitrogen	132-133	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	75-81
10901693-9	2000	The results suggest that UGT1A4 and UGT1A3 catalyze high-K(M) N-glucuronidation of tertiary amine drugs, whereas the low-K(M) reaction requires either an alternative enzyme or a special conformation of UGT1A4 or UGT1A3 that can be attained in liver microsomes, but not in HK293 cell membranes.	Nitrogen	62-63	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	36-42
10901693-9	2000	The results suggest that UGT1A4 and UGT1A3 catalyze high-K(M) N-glucuronidation of tertiary amine drugs, whereas the low-K(M) reaction requires either an alternative enzyme or a special conformation of UGT1A4 or UGT1A3 that can be attained in liver microsomes, but not in HK293 cell membranes.	Nitrogen	62-63	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	212-218
10944147-8	2000	PEPCase kinase activity was, however, greater in maize leaves NO(3)- than in the Cl(-)-treated controls, suggesting that it is responsive to leaf nitrogen supply.	Nitrogen	146-154	phosphoenolpyruvate carboxylase 1	Zea mays	0-7
15630029-10	2005	Intermediate-chain n-3 PUFAs were particularly associated with CHD risk when long-chain n-3 PUFA intake was very low (&lt;100 mg/d); among these men, each 1 g/d of intermediate-chain n-3 PUFA intake was associated with an approximately 50% lower risk of nonfatal MI (HR=0.42; 95% CI=0.23 to 0.75) and total CHD (HR=0.53; 95% CI=0.34 to 0.83).	Nitrogen	1-2	pumilio RNA binding family member 3	Homo sapiens	92-96
18646010-6	2008	siRNA targeting LGALS3, WBSCR17, PHF3, SDC2 and CTNNAL1 partially reversed the GlcNAc-induced phenotypes, suggesting a role for galectin-3/N-glycans, proteoglycans, O-glycans, and junctional cell adhesion.	Nitrogen	3-4	polypeptide N-acetylgalactosaminyltransferase 17	Homo sapiens	24-31
15306546-2	2004	The time to peak of stretch-induced delayed force increase (t(3)) was strongly correlated with MHC isoforms [t(3) given in ms for fiber types containing specified isoforms; means +/- SD with n in parentheses: MHCI 680 +/- 108 (13), MHCIIa 110.5 +/- 10.7 (23), MHCIIx(d) 46.2 +/- 5.2 (20), MHCIIb 23.5 +/- 3.3 (76)].	Nitrogen	29-30	major histocompatibility complex, class I, C	Homo sapiens	95-98
10959842-5	2000	The secreted protein Scabrous (Sca) is a candidate for modulation of N in neural cells.	Nitrogen	69-70	scabrous	Drosophila melanogaster	21-29
10959842-5	2000	The secreted protein Scabrous (Sca) is a candidate for modulation of N in neural cells.	Nitrogen	69-70	scabrous	Drosophila melanogaster	21-24
21203059-2	2008	The Mn(III) ion is hexa-coordinated by two N and two O atoms from two phenolate ligands and two N atoms from two azide ligands.	Nitrogen	96-97	hexosaminidase subunit alpha	Homo sapiens	19-23
10889023-6	2000	PTP1B is able to bind phosphopeptides by utilizing common interactions involving the aromatic ring and phosphate moiety of phosphotyrosine itself, two conserved hydrogen bonds between the Asp48 carboxylate side chain and the main chain nitrogens of the pTyr and residue 1, and a third between the main chain nitrogen of Arg47 and the main chain carbonyl of residue -2.	Nitrogen	236-245	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	0-5
10889023-6	2000	PTP1B is able to bind phosphopeptides by utilizing common interactions involving the aromatic ring and phosphate moiety of phosphotyrosine itself, two conserved hydrogen bonds between the Asp48 carboxylate side chain and the main chain nitrogens of the pTyr and residue 1, and a third between the main chain nitrogen of Arg47 and the main chain carbonyl of residue -2.	Nitrogen	236-244	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	0-5
15292462-0	2004	N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.	Nitrogen	0-1	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	67-73
15355998-8	2004	Oms1p presents one TM and a N-in C-out topology with the C-terminal domain carrying the methyltransferase-like domain.	Nitrogen	28-29	putative RNA methyltransferase	Saccharomyces cerevisiae S288C	0-5
10893314-11	2000	Molecular modeling studies on 12a suggested that the protonated N-17 and guanidinium groups of GNTI are associated with Asp138 (TM3) and Glu297 (TM6), respectively, while the phenolic hydroxyl may be involved in donor-acceptor interactions with the imidazole ring of His291.	Nitrogen	64-65	tropomyosin 3	Homo sapiens	128-131
18633161-5	2008	Blood urea nitrogen (BUN) in Meg1 Tg mice (19.6 +/- 1.2 mg/dl) was significantly lower than in controls (22.0 +/- 0.8 mg/dl), while plasma triglyceride, insulin, adiponectin, and resistin levels were significantly higher (202.0 +/- 23.4 mg/dl vs 146.3 +/- 23.4 mg/dl, 152.4 +/- 16.3 pg/ml vs 88.1 +/- 16.9 pg/ml, 74.4 +/- 10.9 microg/ml vs 48.3 +/- 7.0 microg/ml, and 4.0 +/- 0.2 ng/ml vs 3.6 +/- 0.2 ng/ml, respectively).	Nitrogen	11-19	growth factor receptor bound protein 10	Mus musculus	29-33
10873770-1	2000	The orthopoxvirus serpin SPI-3 is N-glycosylated and suppresses fusion between infected cells.	Nitrogen	34-35	serpin family B member 6	Homo sapiens	25-30
10926165-5	2000	In the present study we demonstrate that purified recombinant human ferrochelatase (FC) provides an extremely sensitive bioassay system for N-alkylPPs and is capable of detecting N-alkylPP in the 10(-6) nmol range.	Nitrogen	140-141	ferrochelatase	Homo sapiens	68-82
10926165-5	2000	In the present study we demonstrate that purified recombinant human ferrochelatase (FC) provides an extremely sensitive bioassay system for N-alkylPPs and is capable of detecting N-alkylPP in the 10(-6) nmol range.	Nitrogen	140-141	ferrochelatase	Homo sapiens	84-86
10926165-5	2000	In the present study we demonstrate that purified recombinant human ferrochelatase (FC) provides an extremely sensitive bioassay system for N-alkylPPs and is capable of detecting N-alkylPP in the 10(-6) nmol range.	Nitrogen	179-180	ferrochelatase	Homo sapiens	68-82
15255780-12	2004	Our results demonstrate that proSAP forms oligomers that are capable of binding proCD spontaneously and independent of the mammalian type N-glycosylation but not capable of binding mature cathepsin D.	Nitrogen	138-139	prosaposin	Homo sapiens	29-35
15494556-6	2004	In Arabidopsis, all nine ATG8 genes and two ATG4 genes were expressed ubiquitously and were induced further by nitrogen starvation.	Nitrogen	111-119	UbiA prenyltransferase family protein	Arabidopsis thaliana	44-48
10926165-5	2000	In the present study we demonstrate that purified recombinant human ferrochelatase (FC) provides an extremely sensitive bioassay system for N-alkylPPs and is capable of detecting N-alkylPP in the 10(-6) nmol range.	Nitrogen	179-180	ferrochelatase	Homo sapiens	84-86
15498570-0	2004	N-glycosylation is required for efficient secretion of a novel human secreted glycoprotein, hPAP21.	Nitrogen	0-1	protease associated domain containing 1	Homo sapiens	92-98
18457328-10	2008	CONCLUSIONS: The current findings suggested that the T/N expression ratios of ATM and DNA-PKcs may be useful for identifying NSCLC patients with a poor prognosis who may benefit from more aggressive therapy.	Nitrogen	2-3	ATM serine/threonine kinase	Homo sapiens	78-81
15498570-5	2004	Interestingly, the extracellular forms were primarily sensitive to PNG F, not Endo H, implying that complex N-glycosylation could be required for the secretion of hPAP21.	Nitrogen	68-69	protease associated domain containing 1	Homo sapiens	163-169
15498364-10	2004	RESULTS: Nitrogen led to significant decreases in mean PO2, from (120.6 +/- 18.9) mmHg to (51.8 +/- 15.9) mmHg (P &lt; 0.01).	Nitrogen	9-17	PO2	Sus scrofa	55-58
15498364-12	2004	The decrease in PO2 post nitrogen resulted in a slight increase in values at rest: 0.46 +/- 0.15 to 0.53 +/- 0.18 for b and (1.39 +/- 0.66) ml x min(-1) x g(-1) to (1.72 +/- 0.30) ml x min(-1) x g(-1) for myocardial blood flow (MBF) (both P &lt; 0.05).	Nitrogen	25-33	PO2	Sus scrofa	16-19
18420581-0	2008	N-linked glycosylation selectively regulates the generic folding of HLA-Cw1.	Nitrogen	0-1	dynein light chain Tctex-type 1	Homo sapiens	72-75
15247302-1	2004	beta(2)-adrenergic receptors (beta(2)AR) of all species are N-linked glycosylated at amino terminus residues approximately 6 and approximately 15.	Nitrogen	60-61	adrenoceptor beta 2	Homo sapiens	0-28
15247302-1	2004	beta(2)-adrenergic receptors (beta(2)AR) of all species are N-linked glycosylated at amino terminus residues approximately 6 and approximately 15.	Nitrogen	60-61	adrenoceptor beta 2	Homo sapiens	30-39
15247302-2	2004	However, the human beta(2)AR has a potential third N-glycosylation site at ECL2 residue 187.	Nitrogen	51-52	adrenoceptor beta 2	Homo sapiens	19-28
18420581-1	2008	To resolve primary (glycosylation-assisted) from secondary (glycosylation-independent) quality control steps in the biosynthesis of HLA (human leukocyte antigen) class I glycoproteins, the unique N-linked glycosylation site of the HLA-Cw1 heavy chain was deleted by site-directed mutagenesis.	Nitrogen	196-197	dynein light chain Tctex-type 1	Homo sapiens	235-238
15313009-1	2004	Human thrombopoietin (hTPO) is a heavily glycosylated protein with 6 and 24 potential N- and O-glycosylation sites, respectively.	Nitrogen	86-87	thyroid peroxidase	Homo sapiens	22-26
18443284-2	2008	Exposure of yeast cells to poor nitrogen sources or treatment with the Tor kinase inhibitor rapamycin elicits activation of Gln3 and transcription of nitrogen catabolite-repressed (NCR) genes whose products function in scavenging and metabolizing nitrogen.	Nitrogen	32-40	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	124-128
15294867-7	2004	Based on the presence of different N- and C-lipid-containing Shh proteins in the rat embryo, and on their different activities, we propose that both N- and C-terminal lipids are required for the formation of multimers involved in long-range signaling, and that the C-terminal lipid may function in long-range signaling by reducing Shh activity until it reaches its long-range target.	Nitrogen	35-36	sonic hedgehog signaling molecule	Rattus norvegicus	61-64
15289885-9	2004	The finding that n-LDL and Ox-LDL induces Cox-2 in human endothelial cells through a p38 MAPK, NF-kappaB, CREB dependent pathway thus modulating PGE2 release, suggests a new mechanism by which these lipoproteins induce endothelial dysfunction, sustaining inflammatory processes in the arterial wall.	Nitrogen	6-7	cAMP responsive element binding protein 1	Homo sapiens	106-110
18443284-3	2008	Here, we show that mutations in class C and D Vps components, which mediate Golgi-to-endosome vesicle transport, impair nuclear translocation of Gln3, NCR gene activation, and growth in poor nitrogen sources.	Nitrogen	191-199	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	145-149
18256203-8	2008	Among the recombinant human UDP glucuronosyltransferase (UGT) isoforms tested, only isoform UGT1A4 catalyzed the N-glucuronidation of MDZ fitting a Michaelis-Menten model.	Nitrogen	113-114	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	92-98
14985924-10	2004	Levels of BDNF were reduced in the striatum of N2-exposed rats, suggesting poorer synaptic performance of dopamine pathways.	Nitrogen	47-49	brain-derived neurotrophic factor	Rattus norvegicus	10-14
18166993-0	2008	Characterization of the N-glycosylation phenotype of erythrocyte membrane proteins in congenital dyserythropoietic anemia type II (CDA II/HEMPAS).	Nitrogen	24-25	SEC23 homolog B, COPII coat complex component	Homo sapiens	131-137
15261287-1	2004	A series of benzimidazole derivatives with the side chain on the nitrogen atom oriented to the prime site of factor Xa (FXa) were designed and synthesized.	Nitrogen	65-73	coagulation factor X	Homo sapiens	109-118
15261287-1	2004	A series of benzimidazole derivatives with the side chain on the nitrogen atom oriented to the prime site of factor Xa (FXa) were designed and synthesized.	Nitrogen	65-73	coagulation factor X	Homo sapiens	120-123
15310245-0	2004	Human UDP-glucuronosyltransferase 1A1 is the primary enzyme responsible for the N-glucuronidation of N-hydroxy-PhIP in vitro.	Nitrogen	80-81	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	6-37
15310245-7	2004	UGT1A1 was the most efficient in converting N-hydroxy-PhIP to both conjugates producing five times more of the N(2)-conjugate than UGT1A4, the next most active UGT, and 286 times more than UGT1A7, the least active UGT.	Nitrogen	111-115	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	0-6
15310245-7	2004	UGT1A1 was the most efficient in converting N-hydroxy-PhIP to both conjugates producing five times more of the N(2)-conjugate than UGT1A4, the next most active UGT, and 286 times more than UGT1A7, the least active UGT.	Nitrogen	111-115	UDP glucuronosyltransferase family 1 member A7	Homo sapiens	189-195
15253935-5	2004	In addition, we showed that N and eyg could induce expression of upd, which encodes the ligand for the Jak/STAT pathway and acts over long distance to promote cell proliferation.	Nitrogen	28-29	Signal-transducer and activator of transcription protein at 92E	Drosophila melanogaster	107-111
15284300-6	2004	Furthermore, inhibition of PBR accelerated the recovery of normal renal function, as assessed by measurement of levels of plasma creatinine and blood urea nitrogen.	Nitrogen	155-163	translocator protein	Rattus norvegicus	27-30
15253727-7	2004	RESULTS: Kallikrein gene delivery resulted in reduced blood urea nitrogen (BUN), urinary protein and albumin levels in DSS rats on a high salt diet.	Nitrogen	65-73	kallikrein related peptidase 4	Homo sapiens	9-19
15183032-6	2004	gp91phox has three potential N-linked glycosylation sites.	Nitrogen	29-30	cytochrome b-245 beta chain	Homo sapiens	0-8
15220431-7	2004	The small number of mutations in viruses selected for CXCR4 use were distinctly nonrandom, with a dominance of charged amino acid substitutions encoded by G-to-A transitions, changes in N-linked glycosylation sites, and isolate-specific mutation patterns.	Nitrogen	186-187	C-X-C motif chemokine receptor 4	Homo sapiens	54-59
15256566-0	2004	The nitrogen-fixing gene (nifH) of Rhodopseudomonas palustris: a case of lateral gene transfer?	Nitrogen	4-12	nitrogenase iron protein	Rhodobacter sphaeroides 2.4.1	26-30
15256566-2	2004	This paper presents a phylogenetic comparison of a nitrogen fixation gene (nifH) with the aim of elucidating the processes underlying the evolutionary history of Rhodopseudomonas palustris.	Nitrogen	51-59	nitrogenase iron protein	Rhodobacter sphaeroides 2.4.1	75-79
15073187-6	2004	The GLUT1 reporter molecule was engineered from C-less GLUT1 by creating a unique cleavage site for factor Xa protease within the central cytoplasmic loop and by eliminating the site of N-linked glycosylation.	Nitrogen	186-187	solute carrier family 2 (facilitated glucose transporter), member 1 L homeolog	Xenopus laevis	4-9
15147511-5	2004	TorsinB (approximately MW 38 kDa), like torsinA ( approximately MW 37 kDa), is an N-glycosylated protein and both reside primarily in the endoplasmic reticulum (ER) and nuclear envelope in cultured cells.	Nitrogen	82-83	torsin family 1 member B	Homo sapiens	0-7
15024013-0	2004	The role of N-glycosylation in function and surface trafficking of the human dopamine transporter.	Nitrogen	12-13	solute carrier family 6 member 3	Homo sapiens	77-97
15024013-1	2004	The present study addressed the role of N-linked glycosylation of the human dopamine transporter (DAT) in its function with the help of mutants, in which canonical N-glycosylation sites have been removed (N181Q, N181Q,N188Q, and N181Q,N188Q,N205Q), expressed in human embryonic kidney-293 cells.	Nitrogen	40-41	solute carrier family 6 member 3	Homo sapiens	76-96
15024013-1	2004	The present study addressed the role of N-linked glycosylation of the human dopamine transporter (DAT) in its function with the help of mutants, in which canonical N-glycosylation sites have been removed (N181Q, N181Q,N188Q, and N181Q,N188Q,N205Q), expressed in human embryonic kidney-293 cells.	Nitrogen	40-41	solute carrier family 6 member 3	Homo sapiens	98-101
15024013-1	2004	The present study addressed the role of N-linked glycosylation of the human dopamine transporter (DAT) in its function with the help of mutants, in which canonical N-glycosylation sites have been removed (N181Q, N181Q,N188Q, and N181Q,N188Q,N205Q), expressed in human embryonic kidney-293 cells.	Nitrogen	164-165	solute carrier family 6 member 3	Homo sapiens	76-96
15024013-1	2004	The present study addressed the role of N-linked glycosylation of the human dopamine transporter (DAT) in its function with the help of mutants, in which canonical N-glycosylation sites have been removed (N181Q, N181Q,N188Q, and N181Q,N188Q,N205Q), expressed in human embryonic kidney-293 cells.	Nitrogen	164-165	solute carrier family 6 member 3	Homo sapiens	98-101
15024013-3	2004	Prevention of N-glycosylation reduced both surface and intracellular DAT.	Nitrogen	14-15	solute carrier family 6 member 3	Homo sapiens	69-72
15024013-6	2004	Non-glycosylated DAT did not transport dopamine as efficiently as wild-type DAT as judged from the sharp reduction in uptake V(max), and prevention of N-glycosylation enhanced the potency of cocaine-like drugs in inhibiting dopamine uptake into intact cells without changing their affinity for DAT when measured in membrane preparations prepared from these cells.	Nitrogen	0-1	solute carrier family 6 member 3	Homo sapiens	17-20
14681336-8	2004	Eliciting IR waves with puffs of nicotinic or non-N-methyl-d-aspartate agonists in GCL produced atropine-sensitive waves in the VZ, demonstrating a unique, retrograde signaling pathway from IR to VZ.	Nitrogen	50-51	germ cell-less 2, spermatogenesis associated	Homo sapiens	83-86
14970212-0	2004	The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.	Nitrogen	24-25	amyloid beta precursor like protein 1	Homo sapiens	80-86
14970212-0	2004	The proteolytic processing of the amyloid precursor protein gene family members APLP-1 and APLP-2 involves alpha-, beta-, gamma-, and epsilon-like cleavages: modulation of APLP-1 processing by n-glycosylation.	Nitrogen	24-25	amyloid beta precursor like protein 1	Homo sapiens	172-178
14970212-7	2004	We show that APLP-1 is the only member of the APP gene family for which processing can be influenced by N-glycosylation.	Nitrogen	104-105	amyloid beta precursor like protein 1	Homo sapiens	13-19
14703519-2	2004	Previous results showed that the H3 domain of syntaxin-1A (S1A) binds to ENaC to reduce N, supporting a role for S1A in the regulation of ENaC trafficking.	Nitrogen	74-75	syntaxin 1A (brain)	Mus musculus	46-57
14703519-2	2004	Previous results showed that the H3 domain of syntaxin-1A (S1A) binds to ENaC to reduce N, supporting a role for S1A in the regulation of ENaC trafficking.	Nitrogen	74-75	syntaxin 1A (brain)	Mus musculus	59-62
14684333-4	2004	In addition, a very short bond of 1.78A between the zinc ion and the coordinated nitrogen atom of the sulfamate moiety is observed, which may explain the high affinity of this inhibitor for hCA II (K(i) of 10nM).	Nitrogen	81-89	carbonic anhydrase 2	Homo sapiens	190-196
15218248-14	2004	For all three hyaluronidase genes, N-glycosylation sites are typical.	Nitrogen	35-36	hemopexin	Sus scrofa	14-27
14718392-5	2004	Transient expression of schistosome PHM (smPHM) revealed functional properties that are different from other PHM proteins; smPHM displays a lower pH-optimum and, when expressed in mammalian cells, is heavily N-glycosylated.	Nitrogen	208-209	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	36-39
15471799-4	2004	Amino acid catabolism is decreased by somatotropin treatment, as indicated by decreases in blood urea nitrogen, urea synthesis, hepatic urea cycle enzyme activity, and amino acid oxidation.	Nitrogen	102-110	somatotropin	Sus scrofa	38-50
14688363-5	2004	Interestingly, IL-23N220L, an N-glycosylation mutant showing reduced expression of excess p40 without changing the level of IL-23, exhibited a higher ratio of IFN-gamma- to IL-4-producing CD4(+) T cell frequency than did wild-type IL-23, suggesting a negative regulatory effect of p40 on Th1-prone immune response induced by IL-23.	Nitrogen	20-21	negative elongation factor complex member C/D	Homo sapiens	288-291
15003365-3	2004	These data suggest that alpha-MSH has a protective effect on cerulein-induced acute pancreatitis and this effect could be attributed, at least in part, to decreased tissue leukocyte infiltration and thus, to decreased pro-inflammatory cytokine production and/or oxygen- and nitrogen-derived reactive metabolite release.	Nitrogen	274-282	proopiomelanocortin	Rattus norvegicus	24-33
14686842-0	2003	Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes.	Nitrogen	32-40	synemin	Homo sapiens	13-16
14686842-10	2003	The Et(2)BCQEB(Et) framework provides both structural flexibility and the desired syn nitrogen donor geometry, thus serving as a good first-generation ligand in this class.	Nitrogen	86-94	synemin	Homo sapiens	82-85
14654433-6	2003	Furthermore, nitrogen was needed in the growth medium in order to maintain ATF1 expression.	Nitrogen	13-21	alcohol O-acetyltransferase	Saccharomyces cerevisiae S288C	75-79
14654433-7	2003	Long-term activation of ATF1 could also be obtained by the addition of the non-metabolisable amino acid homologue beta-L-alanine, showing that the effect of the nitrogen source did not depend on its metabolism.	Nitrogen	161-169	alcohol O-acetyltransferase	Saccharomyces cerevisiae S288C	24-28
14634141-2	2003	Using lectins and glycosidases, we have shown that dg1 displays an N-glycosylation pattern of the complex triantennary type.	Nitrogen	67-68	desmoglein 1	Homo sapiens	51-54
14634141-3	2003	We have found that lectins and glycosidases interfere with N-bound sugar residues on the amino-terminal ectodomain of dg1 and completely abolish, in vitro, the antigenicity of dg1 in most of the patients" sera.	Nitrogen	59-60	desmoglein 1	Homo sapiens	118-121
14634141-3	2003	We have found that lectins and glycosidases interfere with N-bound sugar residues on the amino-terminal ectodomain of dg1 and completely abolish, in vitro, the antigenicity of dg1 in most of the patients" sera.	Nitrogen	59-60	desmoglein 1	Homo sapiens	176-179
14659076-4	2003	The open-reading frame of the MRJP1 homologue (AcMRJP1) was 1299 nucleotides that encoded 433 deduced amino acids with three predicted N-linked glycosylation sites.	Nitrogen	135-136	major royal jelly protein 1	Apis mellifera	30-35
14627656-8	2003	Moreover, we show that blocking soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) function in postsynaptic muscle cells interferes with FasII exocytosis.	Nitrogen	40-41	Fasciclin 2	Drosophila melanogaster	164-169
10925685-7	2000	The TS inhibition rate at the tumor site was lower in recurring cases than in non-recurring cases, and the T/N ratio tended to be higher for DPD in patients with recurrences.	Nitrogen	109-110	dihydropyrimidine dehydrogenase	Homo sapiens	141-144
10901195-18	2000	It is recommended that n-3 PUFA-enriched eggs be used as one source of n-3 PUFA to increase individual consumption to meet the current Canadian recommendations.	Nitrogen	13-14	pumilio RNA binding family member 3	Homo sapiens	27-31
10901195-18	2000	It is recommended that n-3 PUFA-enriched eggs be used as one source of n-3 PUFA to increase individual consumption to meet the current Canadian recommendations.	Nitrogen	13-14	pumilio RNA binding family member 3	Homo sapiens	75-79
10864765-3	2000	This change of mechanism was justified on the basis of the syn and anti rotational conformers of the diene -N((1))=C-C=N((2))- group; the greater stability of the former can be explained by the formation of hydrogen bonds between the proton and the N((1)) and N((2)) nitrogen atoms, giving rise to a very stable five-membered ring.	Nitrogen	267-275	synemin	Homo sapiens	59-62
10841761-3	2000	In this study, we investigated the pH titration behavior of the carboxyl groups of the N-terminal domain of rat CD2 (CD2d1) using the chemical shifts of backbone amide nitrogen-15 ((15)N) and proton NMR resonances, and carboxyl carbon-13 ((13)C) signals.	Nitrogen	168-176	Cd2 molecule	Rattus norvegicus	112-115
10841761-3	2000	In this study, we investigated the pH titration behavior of the carboxyl groups of the N-terminal domain of rat CD2 (CD2d1) using the chemical shifts of backbone amide nitrogen-15 ((15)N) and proton NMR resonances, and carboxyl carbon-13 ((13)C) signals.	Nitrogen	168-176	Cd2 molecule	Rattus norvegicus	117-122
10756055-0	2000	N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates.	Nitrogen	0-1	C-X-C motif chemokine receptor 4	Homo sapiens	26-31
10756055-0	2000	N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates.	Nitrogen	0-1	C-C motif chemokine receptor 5	Homo sapiens	62-66
10756055-2	2000	Here we report on the unexpected observation that the removal of the N-linked glycosylation sites in CXCR4 potentially allows the protein to serve as a universal coreceptor for both X4 and R5 laboratory-adapted and primary HIV-1 strains.	Nitrogen	69-70	C-X-C motif chemokine receptor 4	Homo sapiens	101-106
10736181-1	2000	The N-terminal fragment of adenosine diphosphate (ADP) ribosylation factor 1 (ARF1) is proposed to be involved in the guanosine triphosphate- (GTP-) dependent, reversible association of the protein with membranes through the interaction of not only the N-linked myristoyl chain but also its highly conserved N-terminal hydrophobic residues.	Nitrogen	4-5	ADP ribosylation factor 1	Homo sapiens	27-76
10736181-1	2000	The N-terminal fragment of adenosine diphosphate (ADP) ribosylation factor 1 (ARF1) is proposed to be involved in the guanosine triphosphate- (GTP-) dependent, reversible association of the protein with membranes through the interaction of not only the N-linked myristoyl chain but also its highly conserved N-terminal hydrophobic residues.	Nitrogen	4-5	ADP ribosylation factor 1	Homo sapiens	78-82
10737754-9	2000	Consistent with results reported in the literature for the tropane analogues, removal of the methyl group from the nitrogen atom of 9 leads to a further enhancement in 5-HTT activity.	Nitrogen	115-123	huntingtin	Rattus norvegicus	170-173
10741417-1	2000	We present the entire sequence of the mouse Fat orthologue (mFat1), a protein of 4,588 amino acids with 34 cadherin repeats, 27 potential N-glycosylation sites, five EGF repeats and a laminin A G-motif in its extracellular domain.	Nitrogen	138-139	FAT atypical cadherin 1	Mus musculus	60-65
10736100-6	2000	N-linked, but not O-linked, oligosaccharides of patients" IgA1 were oversialylated, and this seemed to be linked to an excess of SA on the same number of polysaccharides as normal IgA1.	Nitrogen	0-1	immunoglobulin heavy constant alpha 1	Homo sapiens	58-62
10737193-7	2000	Mdtl1 is a slightly acidic protein with a putative signal peptide and a putative N-glycosylation site, and lacks a C-terminal extension.	Nitrogen	81-82	thaumatin-like protein 1a	Malus domestica	0-5
10965118-4	2000	The BACE2 gene product is a 518 amino acid protein with the signature of an aspartic protease, a 20-residue signal peptide, and two putative N-glycosylation sites.	Nitrogen	141-142	beta-secretase 2	Homo sapiens	4-9
10690663-6	2000	Mouse EMSP1 shares 75% amino acid identity with pig EMSP1 and has three potential N-linked glycosylation sites, two of which are conserved in the pig homologue.	Nitrogen	82-83	kallikrein related peptidase 4	Sus scrofa	6-11
10585852-5	1999	We present here results on N-glycan processing of TRP-1 and tyrosinase and compare the maturation process and activity of both glycoproteins in the presence of inhibitors of the endoplasmic reticulum stages of N-glycosylation.	Nitrogen	27-28	tyrosinase-related protein 1	Mus musculus	50-55
10608665-7	1999	Treating detached leaves with t-zeatin or supplying inorganic nitrogen to the whole plant induced the accumulation of ZmRR1 and ZmRR2 transcripts.	Nitrogen	62-70	cytokinin response regulator 2	Zea mays	128-133
10537291-2	1999	Cytochrome P4501A2 (CYP1A2)-mediated N-hydroxylation followed by phase II O-esterification by N-acetyltransferase (NAT2) are generally regarded as activation processes in which MeIQx and other HAAs are converted to genotoxic species.	Nitrogen	37-38	N-acetyltransferase 2	Homo sapiens	115-119
10548047-1	1999	The three N-glycosylation sites of human heparin binding protein (HBP) have been mutated to produce a nonglycosylated HBP (ng-HBP) mutant.	Nitrogen	10-11	azurocidin 1	Homo sapiens	41-64
10548047-1	1999	The three N-glycosylation sites of human heparin binding protein (HBP) have been mutated to produce a nonglycosylated HBP (ng-HBP) mutant.	Nitrogen	10-11	azurocidin 1	Homo sapiens	66-69
10510155-10	1999	CONCLUSIONS: The polymorphic enzyme CYP2C19 catalyses the high-affinity N-demethylation of sertraline, while CYP2C9 is one of the low-affinity components of this metabolic pathway.	Nitrogen	2-3	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	36-43
10469630-3	1999	In vitro metabolism studies with human and rat liver microsomes have shown that CYP1A2 is primarily responsible for catalyzing N-hydroxylation, the initial step in the metabolic activation of 4-ABP.	Nitrogen	127-128	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	80-86
10460803-6	1999	N-demethylation is primarily mediated by CYP2C9, CYP2C8, and CYP1A2; dihydrodiol formation by CYP2C9 and CYP1A2; deamination by CYP3A4; and side chain oxidation equally by CYP1A2, CYP2C8, CYP2C9, and CYP2C19.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	200-207
14632661-11	2003	In addition, preincubation of WT-CD16-transfected cells with Tunicamycin (an inhibitor of N-glycosylation) resulted in an increased binding of monomeric IgG whereas N163Q-CD16-transfected cells remained unaffected.	Nitrogen	90-91	Fc gamma receptor IIIa	Homo sapiens	33-37
14632661-11	2003	In addition, preincubation of WT-CD16-transfected cells with Tunicamycin (an inhibitor of N-glycosylation) resulted in an increased binding of monomeric IgG whereas N163Q-CD16-transfected cells remained unaffected.	Nitrogen	90-91	Fc gamma receptor IIIa	Homo sapiens	171-175
14562042-2	2003	In the present study, we propose that variant N-glycosylation represents an important mechanism for regulation of beta1, but not beta3 or beta5 integrins.	Nitrogen	46-47	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	114-119
12969271-3	2003	Tunicamycin, an inhibitor of N-glycosylation, rapidly induced the expression of the ER-resident chaperone Bip/grp78, a known target gene of the unfolded protein response.	Nitrogen	29-30	heat shock protein family A (Hsp70) member 5	Rattus norvegicus	106-109
12969271-3	2003	Tunicamycin, an inhibitor of N-glycosylation, rapidly induced the expression of the ER-resident chaperone Bip/grp78, a known target gene of the unfolded protein response.	Nitrogen	29-30	heat shock protein family A (Hsp70) member 5	Rattus norvegicus	110-115
10532353-6	1999	Recent study has revealed that a simple collagen model peptide, (Pro-Pro-Gly)n, is recognized by HSP47 as well as by prolyl 4-hydroxylase in vitro (Koide et al., manuscript submitted).	Nitrogen	4-5	serpin family H member 1	Homo sapiens	97-102
18166993-4	2008	In the present study, N-glycosylation of erythrocyte membrane proteins of CDA II patients and controls was investigated by SDS-Page, lectin binding studies, and MALDI-TOF/MS mapping in order to allow an embracing view on the glycosylation defect in CDA II.	Nitrogen	22-23	SEC23 homolog B, COPII coat complex component	Homo sapiens	74-80
12939163-0	2003	N-Glycosylation and conserved cysteine residues in RAMP3 play a critical role for the functional expression of CRLR/RAMP3 adrenomedullin receptor.	Nitrogen	0-1	calcitonin receptor like receptor L homeolog	Xenopus laevis	111-115
18245087-0	2008	Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.	Nitrogen	27-35	allantoate permease	Saccharomyces cerevisiae S288C	47-51
18245087-0	2008	Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.	Nitrogen	27-35	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	84-88
11674633-9	1999	Density functional calculations (B3LYP/6-31G) have been carried out on a series of nitrogen-containing substituted benzylic radicals.	Nitrogen	83-91	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	35-38
18245087-1	2008	The Tor1,2 protein kinases globally influence many cellular processes including nitrogen-responsive gene expression that correlates with intracellular localization of GATA transcription activators Gln3 and Gat1/Nil1.	Nitrogen	80-88	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	197-201
12956774-8	2003	We also showed that N-glycosylation of DARC occurred on N16SS and did not influence antibody and chemokine binding.	Nitrogen	20-21	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	39-43
18245087-2	2008	Gln3-Myc(13) and Gat1-Myc(13) are restricted to the cytoplasm of cells provided with good nitrogen sources, e.g. glutamine.	Nitrogen	90-98	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-4
17983356-1	2008	The extracellular domain of the human leptin receptor (Ob-R) contains 20 potential N-glycosylation sites whose role in leptin binding remains to be elucidated.	Nitrogen	83-84	leptin receptor	Homo sapiens	38-53
14520005-0	2003	350-kDa royal jelly glycoprotein (apisin), which stimulates proliferation of human monocytes, bears the beta1-3galactosylated N-glycan: analysis of the N-glycosylation site.	Nitrogen	126-127	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	104-111
12888891-0	2003	N-glycosylation is required for the surface localization of MUC17 mucin.	Nitrogen	0-1	mucin 17, cell surface associated	Homo sapiens	60-65
12888891-1	2003	The nucleic acid sequence of the human gene, MUC17, indicates that this mucin contains an SEA domain, a transmembrane domain, and putative N-glycosylation sites in the carboxyl terminus.	Nitrogen	139-140	mucin 17, cell surface associated	Homo sapiens	45-50
10475631-5	1999	Phytase supplementation significantly improved the utilisation of N, P, Ca and Zn (as a percentage of intake) and increased the concentration of Ca and Zn in the tibiae (P&lt;0.05) because of higher intakes of dry matter, N, P, Ca and Zn.	Nitrogen	66-68	phytase	Zea mays	0-7
10387077-6	1999	The putative binding site for cTnI(33-80) was determined by mapping amide proton and nitrogen chemical shift changes, induced by the binding of cTnI(33-80), onto the C-terminal cTnC structure.	Nitrogen	85-93	troponin I3, cardiac type	Homo sapiens	30-34
12888891-8	2003	In summary, our results indicate that the surface localization of the smaller subunit of MUC17 is dependent on its N-glycosylation status.	Nitrogen	115-116	mucin 17, cell surface associated	Homo sapiens	89-94
17983356-1	2008	The extracellular domain of the human leptin receptor (Ob-R) contains 20 potential N-glycosylation sites whose role in leptin binding remains to be elucidated.	Nitrogen	83-84	leptin receptor	Homo sapiens	55-59
10342863-6	1999	Deglycosylation studies revealed that the higher-molecular-mass CRES proteins (19 and 17 kDa) were the result of N-linked glycosylation, caused by the presence of high mannose residues.	Nitrogen	113-114	cystatin 8 (cystatin-related epididymal spermatogenic)	Mus musculus	64-68
10429966-6	1999	Detoxification of ammonia by glutamine synthetase may be limited due to a shortage of glutamate when the nitrogen load is high.	Nitrogen	105-113	glutamate-ammonia ligase	Rattus norvegicus	29-49
14529191-3	2003	CAR1 and YGP1 genes are not specifically induced under conditions of nitrogen starvation.	Nitrogen	69-77	nuclear receptor subfamily 1 group I member 3	Homo sapiens	0-4
14529191-4	2003	However, a significant increase in the enzymatic activity of arginase, the product of the CAR1 gene, is detected in vinifications carried out with musts containing limiting amounts of nitrogen.	Nitrogen	184-192	nuclear receptor subfamily 1 group I member 3	Homo sapiens	90-94
18219426-0	2008	Aminobromination of olefins with TsNH(2) and NBS as the nitrogen and bromine sources mediated by hypervalent iodine in a ball mill.	Nitrogen	56-64	nibrin	Homo sapiens	45-48
14499355-1	2003	The aim of this study was to investigate the cytotoxic activity of the third-generation nitrogen-containing bisphosphonate zoledronic acid (ZOL) as a single agent, and in combination with clinically relevant anticancer drugs, in a panel of human osteogenic sarcoma cell lines (HOS, BTK-143, MG-63, SJSA-1, G-292, and SAOS2).	Nitrogen	88-96	Bruton tyrosine kinase	Homo sapiens	282-285
12904166-4	2003	IGFBP-4, the smallest IGFBP, exists in both non-glycosylated and N-glycosylated forms in all biological fluids.	Nitrogen	65-66	insulin like growth factor binding protein 4	Homo sapiens	0-7
10354282-13	1999	Nephritic p21-/- mice had increased extracellular matrix protein accumulation and apoptosis and decreased renal function (serum urea nitrogen) compared with p21+/+ mice (P &lt; 0.001).	Nitrogen	133-141	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	10-13
10384960-10	1999	Cys and N-AcCys also inhibited the fragmentation of histone H4 by CB and their concentration-dependent inhibitory profiles were qualitatively similar to those observed with Z-Arg-Arg-NHMec.	Nitrogen	8-9	cathepsin B	Homo sapiens	66-68
18800177-1	2008	Beta-mannosidase (EC 3.2.1.25, MANB) dissects the non-reducing end of N-linked mannose moieties of glycoproteins in eukaryotic cells.	Nitrogen	33-34	mannosidase beta	Homo sapiens	0-16
10051290-10	1999	CONCLUSIONS: These data demonstrate that unlike n-LDL, ox-LDL upregulates MMP-9 expression while reducing TIMP-1 expression in monocyte-derived macrophages.	Nitrogen	28-29	matrix metallopeptidase 9	Homo sapiens	74-79
12883358-7	2003	Furthermore, we observed that changes in N- and O-glycosylation of CD44s could modulate its cleavage.	Nitrogen	41-42	CD44 molecule (Indian blood group)	Homo sapiens	67-71
18069987-1	2008	An efficient diamination reaction of alkenes has been developed for the synthesis of bromoalkyl-branched imidazolines by using CuI-PPh3 as the catalyst and N,N-dibromo-p-toluenesulfonamide as the nitrogen/halogen sources.	Nitrogen	196-204	protein phosphatase 4 catalytic subunit	Homo sapiens	131-135
12802338-4	2003	The sulphenic acid intermediate produced in response to PTP1B oxidation is rapidly converted into a previously unknown sulphenyl-amide species, in which the sulphur atom of the catalytic cysteine is covalently linked to the main chain nitrogen of an adjacent residue.	Nitrogen	235-243	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	56-61
10077186-6	1999	While this response to nitrogen starvation was likely mediated by the stress-responsive elements (STREs) in the promoter of these genes, we found that these elements were not responsible for the co-induction of genes involved in reserve carbohydrate metabolism during glucose limitation, since GLG1, which does not contain any STRE, was coordinately induced with GSY2 and TPS1.	Nitrogen	23-31	alpha,alpha-trehalose-phosphate synthase (UDP-forming) TPS1	Saccharomyces cerevisiae S288C	372-376
18022966-4	2008	In [Fe(II)(PrL1)(2)](BPh(4))(2) (3) the ligand is facially coordinated to the metal with an N,N,O donor set, whereas in [Fe(II)(PrL1)(2)(MeOH)(2)](OTf)(2) (4) a bidentate N,N binding mode is found.	Nitrogen	92-93	protein tyrosine phosphatase 4A1	Homo sapiens	11-15
10021925-1	1999	Anisylazoformyllysine (CH3OC6H4-N = N-CO-Lys-OH) is rapidly hydrolyzed at the acyl-lysine linkage by the zinc-enzyme porcine carboxypeptidase B.	Nitrogen	32-33	carboxypeptidase B1	Homo sapiens	125-143
10338190-5	1999	In mEC+n at 42 C, the non-starved cells from overnight cultures with an initial density of less than 10(3) colony-forming units (CFU)/ml grew to the density of over 10(7) CFU/ml after 24 hr incubation, whereas those starved for 6 weeks in SRW were only to maintain their initial density or died off after 24 hr incubation under the same culturing conditions.	Nitrogen	1-2	chemokine (C-C motif) ligand 28	Mus musculus	3-6
14749026-17	2003	CONCLUSION: Substitution with methoxy groups at C-7 and/or at C-8 of ring C of 1,4-phenanthrenequinone increases the LUMO coefficients at the 2,3 double bond of ring A and thus facilitates nucleophilic substitution of protein nitrogen or sulfur nucleophiles at this electron-deficient double bond.	Nitrogen	226-234	complement component C7	Cavia porcellus	48-51
12796300-8	2003	Our findings show that perceived nitrogen deprivation triggered by rapamycin treatment and steady-state growth in nitrogen-derepressing conditions are associated with hyperphosphorylation of Put3p and increased PUT1 expression.	Nitrogen	33-41	Put3p	Saccharomyces cerevisiae S288C	191-196
12796300-8	2003	Our findings show that perceived nitrogen deprivation triggered by rapamycin treatment and steady-state growth in nitrogen-derepressing conditions are associated with hyperphosphorylation of Put3p and increased PUT1 expression.	Nitrogen	114-122	Put3p	Saccharomyces cerevisiae S288C	191-196
18689982-6	2008	In addition, we found that inhibition of N-glycosylation increased the ubiquitination and degradation of P-gp and CD147, and affected their function.	Nitrogen	41-42	basigin (Ok blood group)	Homo sapiens	114-119
12639958-6	2003	We found that the N-linked glycosylation sites present in the N- and C-terminal domains of PEN-2 were utilized, whereas a site in the hydrophilic "loop" region connecting the two transmembrane domains was not.	Nitrogen	18-19	presenilin enhancer, gamma-secretase subunit	Homo sapiens	91-96
12762671-1	2003	[reaction: see text] Metalation of a Boc-protected N-silylamine alpha to nitrogen results in migration of the silicon from nitrogen to carbon (reverse aza-Brook rearrangement), yielding an alpha-amino silane.	Nitrogen	73-81	BOC cell adhesion associated, oncogene regulated	Homo sapiens	37-40
12762671-1	2003	[reaction: see text] Metalation of a Boc-protected N-silylamine alpha to nitrogen results in migration of the silicon from nitrogen to carbon (reverse aza-Brook rearrangement), yielding an alpha-amino silane.	Nitrogen	123-131	BOC cell adhesion associated, oncogene regulated	Homo sapiens	37-40
10477134-2	1999	Treatment with hypoxia (5% CO2/94% N2/1% O2) for 6 and 12 h increased expression levels of ADM mRNA 2.2-fold and fivefold compared with the normoxia control, respectively.	Nitrogen	35-37	adrenomedullin	Homo sapiens	91-94
11670831-7	1998	The X-ray crystal structure of syn-GaCl[P(2)N(2)] reveals a trigonal bipyramidal geometry about the metal atom, necessitating the coordination of both phosphorus atoms.	Nitrogen	43-48	synemin	Homo sapiens	31-34
18591835-1	2008	Niemann-Pick C1-like 1 (NPC1L1) has recently been identified and has been shown to have features of a plasma membrane transporter, including a secretion signal, 13 predicted transmembrane domains, extensive N-linked glycosylation sites and a sterol-sensing domain.	Nitrogen	0-1	NPC1 like intracellular cholesterol transporter 1	Homo sapiens	24-30
29711098-1	1998	The high-pressure reaction of solid Ca3 N2 with gold in a nitrogen atomsphere affords the ternary auride nitride Ca2 AuN.	Nitrogen	58-66	carbonic anhydrase 2	Homo sapiens	113-116
9792925-3	1998	We established Chinese hamster ovary (CHO) cell lines to evaluate the biological roles of the N-glycosylation in rat LIF (rLIF).	Nitrogen	94-95	LIF, interleukin 6 family cytokine	Rattus norvegicus	122-126
9785451-3	1998	Our data also show that in nitrogen-limiting conditions Nac is involved in the transcriptional repression of the gdhA gene (encoding glutamate dehydrogenase) except when L-glutamine is used as the only nitrogen source.	Nitrogen	27-35	glutamate dehydrogenase	Escherichia coli	113-117
12739977-3	2003	At C-3, side chains L-CH(2)- and L-CH(2)CH(2)- (L = thioether or phosphine) ensured formation of chelates to a cis-dichloropalladium(II) fragment through side-chain atom L and the pyrazole nitrogen closest to the side chain.	Nitrogen	189-197	complement C3	Homo sapiens	3-6
12739977-4	2003	The significance of the ligands is that by placing a ligating side chain on a ring carbon (C-3), rather than on a ring nitrogen, the ring nitrogen not bound to the metal and its attached proton are available for hydrogen bonding.	Nitrogen	138-146	complement C3	Homo sapiens	91-94
12713833-4	2003	Based on the X-ray crystal structure of the adducts of hCA II with ureate and hydroxamate inhibitors, the hypothetical binding of hydroxyurea is proposed to be achieved in deprotonated state, with the nitrogen atom coordinated to Zn(II), and the OH group of the inhibitor making a hydrogen bond with Thr 199.	Nitrogen	201-209	carbonic anhydrase 2	Homo sapiens	55-61
18267946-3	2008	When compared with the wild-type (WT) control plants, the SAG12::ipt wheat plants exhibited delayed chlorophyll degradation only when grown under limited nitrogen (N) supply.	Nitrogen	154-162	Ipt	Agrobacterium tumefaciens	65-68
12695354-8	2003	So far, one enzyme system capable of reducing N-hydroxylated structures has been identified in pig liver microsomes, consisting of cytochrome b(5), NADH-cytochrome b(5) reductase, and a P450 isoenzyme of the subfamily 2D.	Nitrogen	46-47	cytochrome b	Sus scrofa	131-143
9726882-3	1998	We found that the average contents of carbon and nitrogen for oceanic bacterial assemblages were 12.4 +/- 6.3 and 2.1 +/- 1.1 fg cell-1 (mean +/- standard deviation; n = 6), respectively.	Nitrogen	50-58	carboxyl ester lipase pseudogene	Homo sapiens	130-136
9781839-7	1998	An analysis of the three-dimensional models of the compounds with the C-7 substituted, nitrogen-containing groups revealed that the range of the geometrically optimum distance between the nitrogen and the carbon atoms was from 2.98 to 4.98 A for highly active compounds and from 2.47 to 2.65 A for weakly active compounds.	Nitrogen	188-196	complement C7	Canis lupus familiaris	70-73
12695354-8	2003	So far, one enzyme system capable of reducing N-hydroxylated structures has been identified in pig liver microsomes, consisting of cytochrome b(5), NADH-cytochrome b(5) reductase, and a P450 isoenzyme of the subfamily 2D.	Nitrogen	46-47	mitochondrially encoded cytochrome b	Homo sapiens	153-165
18089754-2	2008	The cationic amino acid transporter type 1 (CAT1) paralogues of murine NIH 3T3 and MDTF cells (mCAT1 and dCAT1, respectively) contain two conserved N-linked glycosylation sites in the third extracellular loop (ECL3, the putative Mo-MLV binding site).	Nitrogen	71-72	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	95-100
12667607-4	2003	In the alg1 and alg2 mutants, complemented with MPG1 gene, N-glycosylation of invertase was in part restored, to a degree comparable to that of the wild-type control.	Nitrogen	59-60	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	16-20
12667615-0	2003	The impact of N- and O-glycosylation on the functions of Glut-1 transporter in human thyroid anaplastic cells.	Nitrogen	14-15	solute carrier family 2 member 1	Homo sapiens	57-63
9781839-8	1998	In conclusion, the C-7 substituted piperazine moiety of the molecules of already-known fluoroquinolone antibiotics may be responsible for the ability to increase cutaneous vascular permeability, whereas T-3762 is practically inactive because the free amino nitrogen of the 1-aminocyclopropyl group is conformationally present at a shorter distance from the carbon atom at position 7 of the ring nucleus.	Nitrogen	257-265	complement C7	Canis lupus familiaris	19-22
18089754-7	2008	Treatment of mCAT1/insG-expressing cells with tunicamycin, an N-linked glycosylation inhibitor, increased the transduction titre.	Nitrogen	62-63	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	13-18
18361375-0	2007	New ligand platforms for developing the chemistry of the Ti=N-NR2 functional group and the insertion of alkynes into the N-N bond of a Ti=N-NPh2 ligand.	Nitrogen	0-1	neurexophilin 2	Homo sapiens	140-144
12721102-17	2003	The highest intrinsic clearance (V(max)/K(m)) was found for CYP1A subfamily, CYP3A4 and CYP2B6 in the case of 5- sulphoxidation, and for CYP2C19, CYP1A subfamily and CYP2B6 in the case of N-demethylation.	Nitrogen	188-189	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	137-144
18361375-0	2007	New ligand platforms for developing the chemistry of the Ti=N-NR2 functional group and the insertion of alkynes into the N-N bond of a Ti=N-NPh2 ligand.	Nitrogen	60-61	neurexophilin 2	Homo sapiens	140-144
12683946-1	2003	Metabolism of the human chorionic gonadotrophin (hCG)- and LHbeta-subunits (hCGbeta, LHbeta) terminates with the urinary excretion of core fragment (hCGbetacf, LHbetacf) molecules that retain antigenic shape and constituent N-linked carbohydrate moieties.	Nitrogen	224-225	luteinizing hormone subunit beta	Homo sapiens	59-65
18076768-4	2007	Sequence analysis identified the presence of Asn 362 (N362), a potential N-linked glycosylation site immediately N-terminal to CD4-binding site (CD4bs) residues in the C3 region of gp120, more frequently in A-R5 Envs than PA-R5 Envs.	Nitrogen	54-55	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	181-186
12683946-1	2003	Metabolism of the human chorionic gonadotrophin (hCG)- and LHbeta-subunits (hCGbeta, LHbeta) terminates with the urinary excretion of core fragment (hCGbetacf, LHbetacf) molecules that retain antigenic shape and constituent N-linked carbohydrate moieties.	Nitrogen	224-225	chorionic gonadotropin subunit beta 3	Homo sapiens	76-83
12683946-1	2003	Metabolism of the human chorionic gonadotrophin (hCG)- and LHbeta-subunits (hCGbeta, LHbeta) terminates with the urinary excretion of core fragment (hCGbetacf, LHbetacf) molecules that retain antigenic shape and constituent N-linked carbohydrate moieties.	Nitrogen	224-225	luteinizing hormone subunit beta	Homo sapiens	85-91
17885809-0	2007	Genome-wide analysis of Arabidopsis responsive transcriptome to nitrogen limitation and its regulation by the ubiquitin ligase gene NLA.	Nitrogen	64-72	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	132-135
17885809-8	2007	The Arabidopsis nitrogen limitation adaptation mutant (nla) is defective in developing the nitrogen limitation adaptive responses.	Nitrogen	16-24	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	55-58
17885809-8	2007	The Arabidopsis nitrogen limitation adaptation mutant (nla) is defective in developing the nitrogen limitation adaptive responses.	Nitrogen	91-99	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	55-58
12646031-6	2003	On the other hand, the reaction of 3 with GMP results in the cleavage of one of the Pt-N(pyridazine) bonds to form an N7,O6-platinated polymer.	Nitrogen	87-88	5'-nucleotidase, cytosolic II	Homo sapiens	42-45
17885809-9	2007	The microarray analysis revealed that the absence of the functional NLA in the nla mutant extensively altered its responsive transcriptome to nitrogen limitation.	Nitrogen	142-150	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	68-71
17885809-9	2007	The microarray analysis revealed that the absence of the functional NLA in the nla mutant extensively altered its responsive transcriptome to nitrogen limitation.	Nitrogen	142-150	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	79-82
12525494-7	2003	However, for only SER33, and not SER3, expression was regulated in relation to the available nitrogen source in a coordinated fashion with SER1 and SER2.	Nitrogen	93-101	phosphoglycerate dehydrogenase SER33	Saccharomyces cerevisiae S288C	18-23
12646921-5	2003	Escape virus contained mutations in the env gene that were unexpectedly sparse, did not map generally to known neutralization epitopes, and involved primarily changes in N-linked glycosylation.	Nitrogen	170-171	endogenous retrovirus group K member 20	Homo sapiens	40-43
17885809-12	2007	This study presents a genome-wide view of Arabidopsis transcriptome response to nitrogen limitation and its regulation by NLA, and provides information to probe the molecular mechanism controlling plant adaptability to nitrogen limitation.	Nitrogen	80-88	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	122-125
17975075-1	2007	The Saccharomyces cerevisiae UGA4 gene, which encodes the gamma-aminobutyric acid (GABA) and delta-aminolaevulinic acid (ALA) permease, is well known to be regulated by the nitrogen source.	Nitrogen	173-181	Uga4p	Saccharomyces cerevisiae S288C	29-33
12612978-3	2003	This finding prompted us to study comparatively the profile of N- and O-glycosylation of IgA1 in the two subgroups.	Nitrogen	63-64	immunoglobulin heavy constant alpha 1	Homo sapiens	89-93
12644691-1	2003	Role of the nitrogen source on the expression of a reporter gene under the control of the Aox1 promoter.	Nitrogen	12-20	uncharacterized protein	Chlamydomonas reinhardtii	90-94
12644691-6	2003	In contrast, the Aox1 expression is strongly dependent on the nitrogen source, being down-regulated by ammonium and stimulated by nitrate.	Nitrogen	62-70	uncharacterized protein	Chlamydomonas reinhardtii	17-21
12644691-10	2003	The observed pattern of AOX regulation points to the possible interaction between chloroplast and mitochondria in relation to a potential increase of photogenerated ATP when nitrate is used as a nitrogen source.	Nitrogen	195-203	uncharacterized protein	Chlamydomonas reinhardtii	24-27
17975075-4	2007	Although vast amounts of evidence have been gathered about UGA4 regulation by nitrogen, little is known about its regulation by the carbon source.	Nitrogen	78-86	Uga4p	Saccharomyces cerevisiae S288C	59-63
18000603-1	2007	Human coagulation factor VII (FVII) has two N-glycosylation sites (N145 and N322) and two O-glycosylation sites (S52 and S60).	Nitrogen	44-45	coagulation factor VII	Cricetulus griseus	6-28
12926555-8	2003	The observed changes indicate an impairment of N-deethylation, i.e. a possible decrease in enzymatic activity of CYP3A2 and CYP1A2, which are the major enzymes catalyzing this reaction.	Nitrogen	47-48	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	124-130
17909004-7	2007	These data suggest that UGT2B10 is the major hepatic enzyme involved in nicotine/cotinine glucuronidation and that the UGT2B10*2 variant significantly reduces nicotine- and cotinine-N-glucuronidation formation and plays an important role in nicotine metabolism and elimination.	Nitrogen	182-183	UDP glucuronosyltransferase family 2 member B10	Homo sapiens	119-126
12446686-3	2003	Here we have used the yeast system to study translocation of the C terminus of a tagged form of mammalian cytochrome b(5), carrying an N-glycosylation site in its C-terminal domain (b(5)-Nglyc).	Nitrogen	135-136	mitochondrially encoded cytochrome b	Homo sapiens	106-118
17660514-10	2007	Mutations altering the two N-glycosylation sites in the protease domain of rat corin prevented its activation in HEK 293 and HL-1 cells.	Nitrogen	27-28	corin, serine peptidase	Rattus norvegicus	79-84
12489124-1	2003	The role of Gln3p, Nil1p, Dal80p and Ure2p in the nitrogen regulation of ASP3, which codes for the periplasmic Saccharomyces cerevisiae asparaginase II, was investigated.	Nitrogen	50-58	Dal80p	Saccharomyces cerevisiae S288C	26-32
12489124-4	2003	Enzyme activity doubled upon nitrogen starvation of either ammonium-grown (possibly due to Nil2p/Deh1p derepression) or proline-grown (due to Dal80p derepression) cells.	Nitrogen	29-37	Dal80p	Saccharomyces cerevisiae S288C	142-148
17680041-2	2007	The X-ray crystal structures of three of these assemblies have been solved showing them to be the [2+2] metallo-macrocycles [Pd(P-P)(n)]2(OTf)4 [P-P=dppp, n=1, (); P-P=dppp, n=2, (); P-P=dppf, n=1, ()].	Nitrogen	133-135	POU class 5 homeobox 1	Homo sapiens	138-143
14642531-4	2003	This polarity did not correlate with glycosylation, as IL-8 and MIC-1 are both N-glycosylated, but were sorted to opposite sides of the cell.	Nitrogen	79-80	growth differentiation factor 15	Homo sapiens	64-69
17764255-8	2007	Furthermore, solar photon excitation of N(2) leading to the production of c(4) (")(0) may provide useful data required for evaluating and analyzing dayglow models relevant to the interpretation of c(4) (")(0) in the atmospheres of Earth, Jupiter, Saturn, Titan, and Triton.	Nitrogen	40-44	complement C4A (Rodgers blood group)	Homo sapiens	74-78
17764255-8	2007	Furthermore, solar photon excitation of N(2) leading to the production of c(4) (")(0) may provide useful data required for evaluating and analyzing dayglow models relevant to the interpretation of c(4) (")(0) in the atmospheres of Earth, Jupiter, Saturn, Titan, and Triton.	Nitrogen	40-44	complement C4A (Rodgers blood group)	Homo sapiens	197-201
17597618-3	2007	Immunohistochemistry and western blot validated that n-CLU was present in normal tientsin albinao 2 and tientsin albinao 1 mammary epithelium, and secretory clusterin expressed in the cytoplasm of normal tientsin albinao 2 mammary epithelium and spontaneous breast cancer.	Nitrogen	4-5	clusterin	Mus musculus	55-58
17409271-5	2007	The more reactive N-chloro metabolite forms an adduct with N-acetylhistidine, and covalent binding was observed when radiolabeled lamotrigine was incubated with myeloperoxidase/H(2)O(2)/Cl(-).	Nitrogen	18-19	myeloperoxidase	Rattus norvegicus	161-176
17591551-1	2007	Using the avidin-biotin system as model, we investigate here the effective application of [Tc(N)L(PNP)](+/0) technology (L=N-functionalized cysteine [O(-),S(-)]; PNP=aminodiphosphine) to the preparation of target-specific radiopharmaceuticals.	Nitrogen	94-95	purine-nucleoside phosphorylase	Mus musculus	98-101
17591551-1	2007	Using the avidin-biotin system as model, we investigate here the effective application of [Tc(N)L(PNP)](+/0) technology (L=N-functionalized cysteine [O(-),S(-)]; PNP=aminodiphosphine) to the preparation of target-specific radiopharmaceuticals.	Nitrogen	94-95	purine-nucleoside phosphorylase	Mus musculus	162-165
17718058-2	2007	Here we report the serial finding of N-glycosylation profiles of IgG-kappa M-protein in a patient with multiple myeloma monitored for two years.	Nitrogen	37-38	myomesin 2	Homo sapiens	75-84
17439949-7	2007	The response of Gln3-Myc13 localization to stressful conditions can completely overwhelm its response to nitrogen source quality or inhibitor-generated disruption of the Tor1,2 signal transduction pathway.	Nitrogen	105-113	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	16-20
17563389-0	2007	Functional consequences of alteration of N-linked glycosylation sites on the neurokinin 1 receptor.	Nitrogen	41-42	tachykinin receptor 1	Homo sapiens	77-98
9703474-0	1998	Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.	Nitrogen	125-126	solute carrier family 6 member 3	Homo sapiens	213-233
17563389-1	2007	The neurokinin 1 receptor (NK1R), a G protein-coupled receptor involved in diverse functions including pain and inflammation, has two putative N-linked glycosylation sites, Asn-14 and Asn-18.	Nitrogen	27-28	tachykinin receptor 1	Homo sapiens	4-25
9744570-1	1998	A newly synthesized compound, 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)]amino-N-(4-chlorocinnamyl )-N-methylbenzylamine (CKA-1306), was found to inhibit cyclic AMP-dependent protein kinase (PKA) and Ca2+/calmodulin-dependent protein kinase I (CaMK I) with IC50 values of 1.6+/-0.14 and 2.5+/-0.16 microM, respectively.	Nitrogen	33-34	calcium/calmodulin dependent protein kinase I	Homo sapiens	204-246
9744570-1	1998	A newly synthesized compound, 2-[N-(2-aminoethyl)-N-(5-isoquinolinesulfonyl)]amino-N-(4-chlorocinnamyl )-N-methylbenzylamine (CKA-1306), was found to inhibit cyclic AMP-dependent protein kinase (PKA) and Ca2+/calmodulin-dependent protein kinase I (CaMK I) with IC50 values of 1.6+/-0.14 and 2.5+/-0.16 microM, respectively.	Nitrogen	33-34	calcium/calmodulin dependent protein kinase I	Homo sapiens	248-254
9720053-7	1998	However, in medium with BSA as sole nitrogen source, constitutive expression of SAP2 enabled S. cerevisiae to grow and increased the growth rate of C. albicans.	Nitrogen	36-44	glycosylphosphatidylinositol-alpha 1,2 mannosyltransferase	Saccharomyces cerevisiae S288C	80-84
17563389-2	2007	We studied the role of N-linked glycosylation in the functioning of the NK1R by constructing three receptor mutants: two single mutants (Asn --&gt; Gln-14 and Asn --&gt; Gln-18) and a double mutant, lacking both glycosylation sites.	Nitrogen	23-24	tachykinin receptor 1	Homo sapiens	72-76
9745867-7	1998	The effect of 100KF on glomerular ecto-ATPase was oxygen dependent (32.98+/-2.14 under air vs. 65.20+/-5.53 under nitrogen, P&lt; or =0.01), in contrast to the 100KF-induced loss of glomerular sialoglycoproteins that was not significantly altered under nitrogen (62.67+/-10.08 under air vs. 61.74+/-26.05 under nitrogen).	Nitrogen	114-122	CEA cell adhesion molecule 1	Rattus norvegicus	34-45
17517610-1	2007	The central nitrogen metabolic circuit in enteric bacteria consists of three enzymes: glutamine synthetase, glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	12-20	glutamate dehydrogenase 1	Homo sapiens	140-163
9675139-5	1998	This suggests the presence of a dominant hydrocarbon binding site which effectively restricts the access of short-medium chain n-alkyl substrates to the perferryl species in the active site of rabbit CYP4B1.	Nitrogen	23-24	cytochrome P450 4B1	Oryctolagus cuniculus	200-206
17517610-1	2007	The central nitrogen metabolic circuit in enteric bacteria consists of three enzymes: glutamine synthetase, glutamate synthase (GOGAT), and glutamate dehydrogenase (GDH).	Nitrogen	12-20	glutamate dehydrogenase 1	Homo sapiens	165-168
17494733-8	2007	Its abundance varies rapidly with physiological conditions that deeply affect expression of the petA gene in vivo, for instance in aging cultures or upon changes in nitrogen availability.	Nitrogen	165-173	cytochrome f	Chlamydomonas reinhardtii	96-100
9642297-4	1998	Our results demonstrate that sequential proteolytic cleavage within the ectodomain of the 50-kDa pro-AR form leads to release of a predominant N-glycosylated 43-kDa soluble AR, as well as the appearance of other cellular and soluble AR forms.	Nitrogen	143-144	amphiregulin	Homo sapiens	173-175
9720213-4	1998	rLIF expression in COS7 cells resulted in seven molecular species being produced with zero to six N-glycosyl moieties.	Nitrogen	98-99	LIF, interleukin 6 family cytokine	Rattus norvegicus	0-4
17368469-8	2007	Consequently, the mixed N6-PEG treatment showed a much higher S/N ratio than for the corresponding beads treated with bovine serum albumin (BSA), a conventional blocking reagent.	Nitrogen	24-25	progestagen associated endometrial protein	Homo sapiens	27-30
9720213-5	1998	Mutated rLIF proteins with substitutions at the seven possible N-glycosylation sites were also expressed.	Nitrogen	63-64	LIF, interleukin 6 family cytokine	Rattus norvegicus	8-12
9720213-6	1998	An analysis of the molecular weight of the mutated rLIF confirmed the six N-glycosylation sites.	Nitrogen	74-75	LIF, interleukin 6 family cytokine	Rattus norvegicus	51-55
9634539-3	1998	The molecular diversity of CD44 isoforms is further compounded by differential biosynthetic processes and post-translational modifications [e.g. N-/O-glycosylation or glycosaminoglycan (GAG) addition].	Nitrogen	145-146	CD44 molecule (Indian blood group)	Homo sapiens	27-31
17696012-1	2007	Aminylferrocene(FcAI)-Nanogold(NG) modified glassy carbon electrode (FcAI/NG/GCE) was prepared by the Au-N bond between Au and FcAI.	Nitrogen	22-23	aminomethyltransferase	Homo sapiens	69-80
17322565-6	2007	Finally, we introduced Asn-116 of EL into the analogous positions within LPL and HL, resulting in N-linked glycosylation at this site.	Nitrogen	98-99	lipoprotein lipase	Homo sapiens	73-76
9649574-6	1998	We show that OP-1 preserves kidney function, as determined by reduced blood urea nitrogen and serum creatinine, and increased survival rate when administered 10 min before or 1 or 16 h after ischemia, and then at 24-h intervals up to 72 h after reperfusion.	Nitrogen	81-89	bone morphogenetic protein 7	Homo sapiens	13-17
9675899-2	1998	The two genes AAP1 and AAP2 encode broad specificity H(+)-amino acid co-transporters and are expressed to high levels in siliques of Arabidopsis, indicating a potential role in supplying the seeds with organic nitrogen.	Nitrogen	210-218	amino acid permease 1	Arabidopsis thaliana	14-18
17220172-5	2007	We showed that the molecular basis of this defect in N- and O-glycosylation is caused by the disruption of the Cog1-Cog8 interaction due to truncation.	Nitrogen	53-54	component of oligomeric golgi complex 1	Homo sapiens	111-115
9675899-2	1998	The two genes AAP1 and AAP2 encode broad specificity H(+)-amino acid co-transporters and are expressed to high levels in siliques of Arabidopsis, indicating a potential role in supplying the seeds with organic nitrogen.	Nitrogen	210-218	amino acid permease 2	Arabidopsis thaliana	23-27
9675899-6	1998	The endosperm expression of AAP1 during early stages of seed development indicates that the endosperm serves as a transient storage tissue for organic nitrogen.	Nitrogen	151-159	amino acid permease 1	Arabidopsis thaliana	28-32
17344427-4	2007	HIF-2alpha knockdown mice were more susceptible to renal IRI, as indicated by elevated blood urea nitrogen levels and semiquantitative histologic analysis.	Nitrogen	98-106	endothelial PAS domain protein 1	Mus musculus	0-10
9575816-10	1998	These findings indicate that a 178-kDa glucose-inducible phosphoprotein binds to an (ACCCC)n-containing sequence in the 3"-UTR of the FAS mRNA within the same time frame that glucose stabilizes the FAS message.	Nitrogen	8-9	fatty acid synthase	Homo sapiens	198-201
12777058-5	2003	Aglycosylated IgG1 obtained by treatment of the anaphylactic IgG1-producing hybridoma line with an inhibitor of N-glycosylation failed to elicit anaphylaxis.	Nitrogen	112-113	LOC105243590	Mus musculus	14-18
12777058-7	2003	These results suggest that the anaphylactic activity of IgG1 antibodies is closely related to their structural conformation and the proper N-glycosylation of these molecules.	Nitrogen	139-140	LOC105243590	Mus musculus	56-60
9497243-3	1998	Transfection of the ARSE full-length cDNA, in Cos7 cells, allowed us to establish that its protein product is a 60-kD precursor, which is subject to N-glycosylation, to give a mature 68-kD form that, unique among sulfatases, is localized to the Golgi apparatus.	Nitrogen	39-40	arylsulfatase L	Homo sapiens	20-24
17053893-4	2007	The examination of transcript levels showed that the general flavonoid pathway regulators PAP1 and PAP2 were up-regulated in response to nitrogen deficiency in wild type as well as pap1D plants.	Nitrogen	137-145	phosphatidic acid phosphatase 1	Arabidopsis thaliana	90-94
9501125-0	1998	Specific soybean lipoxygenases localize to discrete subcellular compartments and their mRNAs are differentially regulated by source-sink status Members of the lipoxygenase multigene family, found widely in eukaryotes, have been proposed to function in nitrogen partitioning and storage in plants.	Nitrogen	253-261	linoleate 9S-lipoxygenase-4	Glycine max	160-172
9501125-8	1998	Specific lipoxygenase isoforms may have a role in short-term nitrogen storage (VLXC/D), whereas others may simultaneously function in assimilate partitioning as active enzymes (VLXA/B).	Nitrogen	62-70	linoleate 9S-lipoxygenase-4	Glycine max	10-22
9479038-4	1998	The predicted TM4SF5 protein with 197 amino acids contains three NH2-terminal hydrophobic transmembrane regions, followed by an extracellular hydrophilic domain containing two potential N-linked glycosylation sites and a COOH-terminal hydrophobic transmembrane region.	Nitrogen	65-66	transmembrane 4 L six family member 5	Homo sapiens	14-20
12569427-1	2003	Opaque2 (O2) is a bZIP transcriptional regulatory factor involved in the control of seed storage proteins synthesis as well as carbon and nitrogen metabolism during maize seed development.	Nitrogen	138-146	regulatory protein opaque-2	Zea mays	0-7
12569427-1	2003	Opaque2 (O2) is a bZIP transcriptional regulatory factor involved in the control of seed storage proteins synthesis as well as carbon and nitrogen metabolism during maize seed development.	Nitrogen	138-146	regulatory protein opaque-2	Zea mays	9-11
12490617-2	2003	A linear relationship was observed such that increasing n-alkyl chain length provided increased affinity for the alpha4beta2* nicotinic acetylcholine receptor (nAChR) subtype, with the exception of N-n-octylnicotinium iodide (NONI).	Nitrogen	4-5	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	126-158
12490617-2	2003	A linear relationship was observed such that increasing n-alkyl chain length provided increased affinity for the alpha4beta2* nicotinic acetylcholine receptor (nAChR) subtype, with the exception of N-n-octylnicotinium iodide (NONI).	Nitrogen	4-5	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	160-165
17053893-4	2007	The examination of transcript levels showed that the general flavonoid pathway regulators PAP1 and PAP2 were up-regulated in response to nitrogen deficiency in wild type as well as pap1D plants.	Nitrogen	137-145	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	99-103
12685043-4	2003	The use of an artificial electron carrier that shuttles electrons between the plastoquinone pool and plastocyanin, bypassing cytochrome b/f complex, enhanced the photosynthetic electron transport activity five to six fold during nitrogen fixation.	Nitrogen	229-237	mitochondrially encoded cytochrome b	Homo sapiens	125-137
9544242-4	1998	The amount of Can1p present in exponential cells grown on various nitrogen sources is the same, except in arginine-grown cells, in which the amount of the protein is markedly lower.	Nitrogen	66-74	arginine permease CAN1	Saccharomyces cerevisiae S288C	14-19
17053893-5	2007	Interestingly, PAP2 responded much stronger to nitrogen deficiency than PAP1, 200- and 6-fold increase in transcript levels, respectively, for wild-type seedlings.	Nitrogen	47-55	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	15-19
12685043-8	2003	These results suggest that during nitrogen fixation, when the photosynthetic electron transport from PSII is inhibited at the level of cytochrome b/f complex, an alternate electron donor system for PSI may be required for the cells to carry out light dependent nitrogen fixation.	Nitrogen	34-42	mitochondrially encoded cytochrome b	Homo sapiens	135-147
12685043-8	2003	These results suggest that during nitrogen fixation, when the photosynthetic electron transport from PSII is inhibited at the level of cytochrome b/f complex, an alternate electron donor system for PSI may be required for the cells to carry out light dependent nitrogen fixation.	Nitrogen	261-269	mitochondrially encoded cytochrome b	Homo sapiens	135-147
17053893-10	2007	Together with MYB factors, especially PAP2, GL3 appears to be the BHLH partner for anthocyanin accumulation in response to nitrogen deficiency.	Nitrogen	123-131	Purple acid phosphatases superfamily protein	Arabidopsis thaliana	38-42
12489987-0	2002	Infection of cells expressing CXCR4 mutants lacking N-glycosylation at the N-terminal extracellular domain is enhanced for R5X4-dualtropic human immunodeficiency virus type-1.	Nitrogen	52-53	C-X-C motif chemokine receptor 4	Homo sapiens	30-35
17355433-0	2007	A mutation in NLA, which encodes a RING-type ubiquitin ligase, disrupts the adaptability of Arabidopsis to nitrogen limitation.	Nitrogen	107-115	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	14-17
12489987-2	2002	Both, gp120 and CXCR4 are subject to N-glycosylation.	Nitrogen	37-38	C-X-C motif chemokine receptor 4	Homo sapiens	16-21
12489987-4	2002	METHODS: The two CXCR4 N-glycosylation sites g1 (NYT) and g2 (NVS) were mutated by changing the first or third amino acids N or T/S to Q and A respectively (g1; N11Q or T13A; g2, N176Q or S178A).	Nitrogen	23-24	C-X-C motif chemokine receptor 4	Homo sapiens	17-22
17355433-4	2007	Here we isolated an Arabidopsis mutant, nla (nitrogen limitation adaptation), and identified the NLA gene as an essential component in this molecular mechanism.	Nitrogen	45-53	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	40-43
17355433-4	2007	Here we isolated an Arabidopsis mutant, nla (nitrogen limitation adaptation), and identified the NLA gene as an essential component in this molecular mechanism.	Nitrogen	45-53	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	97-100
17355433-5	2007	Supplied with insufficient inorganic nitrogen (nitrate or ammonium), the nla mutant failed to develop the essential adaptive responses to nitrogen limitation, but senesced much earlier and more rapidly than did the wild type.	Nitrogen	37-45	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	73-76
17355433-5	2007	Supplied with insufficient inorganic nitrogen (nitrate or ammonium), the nla mutant failed to develop the essential adaptive responses to nitrogen limitation, but senesced much earlier and more rapidly than did the wild type.	Nitrogen	138-146	SPX (SYG1/Pho81/XPR1) domain-containing protein	Arabidopsis thaliana	73-76
17214981-5	2007	Furthermore, excess pyrophosphate-resembling bisphosphonates prevent nitrogen-containing-bisphosphonate-induced accumulation of unprenylated Rap1A, p38 phosphorylation and growth inhibition in human MDA-MB-231 breast cancer and mouse AB-12 mesothelioma cells.	Nitrogen	69-77	RAP1A, member of RAS oncogene family	Homo sapiens	141-146
12452719-2	2002	The spin distributions obtained from experiment and from theory are consistent and reflect a larger spin delocalization from the Ni atom due to the more covalent character of the Ni-N bonds compared to the Mn-O ones.	Nitrogen	129-130	spindlin 1	Homo sapiens	4-8
12452719-2	2002	The spin distributions obtained from experiment and from theory are consistent and reflect a larger spin delocalization from the Ni atom due to the more covalent character of the Ni-N bonds compared to the Mn-O ones.	Nitrogen	129-130	spindlin 1	Homo sapiens	100-104
12433823-10	2002	In conclusion, the involvement of UGT1A1 and UGT1A9 as well as UGT1A4 in nicotine and cotinine N-glucuronidations in human liver microsomes was suggested, although the contributions of each UGT isoform could not be determined conclusively.	Nitrogen	95-96	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	34-40
17126899-3	2007	We investigated the regulatory effect of highly N-acetylated COS (NACOS) on tumor necrosis factor-alpha (TNF-alpha)-induced endothelial cell (EC) E-selectin expression, which is crucial for leukocyte recruitment.	Nitrogen	48-49	selectin E	Homo sapiens	146-156
12489111-3	2002	The hepatic pathway proceeds via a two-step process involving N-hydroxylation by cytochrome P4501A2 and subsequent O-acetylation by N-acetyltransferase-2.	Nitrogen	62-63	N-acetyltransferase 2	Rattus norvegicus	132-153
12447888-1	2002	Human plasma-derived antithrombin III (AT-III), factor IX (FIX) and vitronectin (VN) were characterized as native glycoproteins and in their de-N-glycosylated form by means of MALDI mass spectrometry.	Nitrogen	82-83	vitronectin	Homo sapiens	68-79
12151387-3	2002	The newly synthesized EAAC1 protein was co-translationally N-glycosylated with high mannose oligosaccharide chains that were processed into complex-type sugar chains as the protein matured.	Nitrogen	59-60	solute carrier family 1 member 1	Rattus norvegicus	22-27
17158203-5	2007	The mutation of the putative N-linked glycosylation site (Asn(36)) decreased cAMP production and reduced cell surface expression to 37% of the wild-type LGR7.	Nitrogen	29-30	relaxin family peptide receptor 1	Homo sapiens	153-157
12270758-7	2002	In KMD-3213, amine of ethyl amine chain and indoline nitrogen of this compound possibly interact within TM3 and TM5 of alpha(1)-ARs.	Nitrogen	53-61	tropomyosin 3	Homo sapiens	112-115
12270758-8	2002	Amide nitrogen of KMD-3213 also interacts within TM4 of alpha(1A)-AR.	Nitrogen	6-14	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	56-64
12271485-10	2002	Because glucose is liberated from oligosaccharides during N-linked glycosylation events in the rough ER, we propose that GLUT8 may serve to transport glucose out of the rough ER into the cytosol and in this manner contribute to glucose homeostasis in hippocampal neurons.	Nitrogen	58-59	solute carrier family 2 member 8	Rattus norvegicus	121-126
17154266-7	2007	Testing for colocalization with GMR-driven n-Syb-GFP labeling revealed that Tan expression is confined to the photoreceptor cells R1-R8.	Nitrogen	5-6	tantalus	Drosophila melanogaster	76-79
12592703-1	2002	The UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase catalyzes the first and committed step in the dolichol cycle, thus playing a fundamental role in the pathway for protein N-glycosylation.	Nitrogen	11-12	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	26-48
17093189-5	2007	HCoV-229E infection was blocked by an N-glycosylation sequon present between aa 288 to 290 in murine APN.	Nitrogen	38-39	alanyl (membrane) aminopeptidase	Mus musculus	101-104
12244074-8	2002	Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.	Nitrogen	12-13	CD44 molecule (Indian blood group)	Homo sapiens	61-65
17009375-7	2007	The reactions of [E(AuPPh(2)CH(2)CH(2)py)(3)]BF(4) with silver and copper salts give complexes with [E(AuPPh(2)CH(2)CH(2)py)(3)M](2+) stoichiometry (E=O, S, Se; M=Ag, Cu) with the metal bonded to the three nitrogen atoms in the absence of AuM interactions.	Nitrogen	206-214	phosphoglycolate phosphatase	Homo sapiens	239-242
12399106-9	2002	Furthermore, chronic OFQ/N exposure increased levels of the TH gene repressor, Oct-2, irrespective of the presence or absence of morphine.	Nitrogen	25-26	POU class 2 homeobox 2	Homo sapiens	79-84
17192711-4	2007	OPRT showed the highest T/N ratio (the ratio of each enzyme activity in tumor areas to that in nontumor areas).	Nitrogen	26-27	uridine monophosphate synthetase	Homo sapiens	0-4
12201734-2	2002	Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.	Nitrogen	129-130	synemin	Homo sapiens	11-14
12400683-1	2002	The maize response regulator genes ZmRR1 and ZmRR2 respond to cytokinin, and the translated products seem to be involved in nitrogen signal transduction mediated by cytokinin through the His-Asp phosphorelay.	Nitrogen	124-132	cytokinin response regulator 2	Zea mays	45-50
17268188-1	2007	Unlike mammals, bony fish appear to possess multiple genes encoding glutamine synthetase (GS), the nitrogen metabolism enzyme responsible for the conversion of glutamate and ammonia into glutamine at the expense of ATP.	Nitrogen	99-107	glutamine synthetase	Oncorhynchus mykiss	68-88
12400683-8	2002	These results suggest that ZmRR1 and ZmRR2 are induced in mesophyll cells and function in nitrogen signal transduction mediated by cytokinin.	Nitrogen	90-98	cytokinin response regulator 2	Zea mays	37-42
16841181-0	2007	N-linked glycosylation of CD38 is required for its structure stabilization but not for membrane localization.	Nitrogen	0-1	CD38 molecule	Homo sapiens	26-30
12208867-3	2002	Both ABCG5 and ABCG8 underwent N-linked glycosylation.	Nitrogen	31-32	ATP binding cassette subfamily G member 8	Homo sapiens	15-20
12167057-9	2002	For a crowded structure such as triisopropylamine, for which the alphaC(*) orbital is not coplanar with the nitrogen one, the relaxation of a strain energy allows the BDE to be comparable to flexible structures.	Nitrogen	108-116	homeobox D13	Homo sapiens	167-170
12130726-15	2002	Furthermore, results obtained with the N-methyl-exo-THPO prodrug demonstrate the feasibility of developing a glial-selective GABA uptake inhibitor with systemic bioavailability.	Nitrogen	39-40	thrombopoietin	Mus musculus	52-56
16841181-3	2007	To determine the structural/functional significance of glycosylation of the human CD38, the four potential N-linked glycosylation sites asparagine residues, N100, N164, N209 and N219 were mutated.	Nitrogen	107-108	CD38 molecule	Homo sapiens	82-86
16841181-8	2007	Moreover, MCF-7 cells stably transfected with CD38wt cDNA, also revealed the presence of cross-linked oligomers when treated with a N-linked glycosylation inhibitor tunicamycin (TM).	Nitrogen	55-56	CD38 molecule	Homo sapiens	46-50
16841181-9	2007	These results suggested that the N-linked glycosylation of CD38 plays a crucial role in the structure stability by preventing the formation inter-molecular cross-links.	Nitrogen	33-34	CD38 molecule	Homo sapiens	59-63
17156807-1	2007	Cyclophosphamide (CTX) is in the nitrogen mustard group of alkylating antineoplastic chemotherapeutic agents.	Nitrogen	33-41	V-set and immunoglobulin domain containing 2	Mus musculus	18-21
12126417-4	2002	Protonation on nitrogen leads to nucleophilic attack at the C-3 carbon and yields C-3 products.	Nitrogen	15-23	complement C3	Homo sapiens	60-63
12126417-4	2002	Protonation on nitrogen leads to nucleophilic attack at the C-3 carbon and yields C-3 products.	Nitrogen	15-23	complement C3	Homo sapiens	82-85
17070532-6	2006	CE-LIF, on the other hand, produces S/N ratios that are &gt;25 times higher than FCM for all the microspheres tested and a lower RSD for microspheres with &lt;1.5 x 10(6) MESF.	Nitrogen	38-39	LIF interleukin 6 family cytokine	Homo sapiens	3-6
12000744-2	2002	In this report, we show that full-length ADAM12 is N-glycosylated in the endoplasmic reticulum (ER) and proteolytically processed in the trans-Golgi network to an approximately 90-kDa form.	Nitrogen	51-52	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	Mus musculus	41-47
12083916-1	2002	Irradiation of N(2) matrix-isolated 3-chloro-3-(2-benzoxazolyl)diazirine gives a mixture of syn- and anti-benzoxazolylchlorocarbenes which could be characterized by IR, UV/vis, and B3LYP modeling.	Nitrogen	15-19	synemin	Homo sapiens	92-95
9414483-0	1998	Identification of the Yc1 glutathione S-transferase mRNA as the overexpressed species in a nitrogen mustard-resistant rat mammary carcinoma cell line.	Nitrogen	91-99	glutathione S-transferase alpha 1	Rattus norvegicus	22-25
17199367-1	2006	Depending on each nitrogen atom of adenine molecule to which a silver atom of a metallic tip approaches, tip-enhanced near-field Raman spectroscopy may show a potential to achieve atomic site-selective detection sensitivity.	Nitrogen	18-26	TOR signaling pathway regulator	Homo sapiens	89-92
9522277-0	1998	N-dealkylation of aminopyrine catalyzed by soybean lipoxygenase in the presence of hydrogen peroxide.	Nitrogen	0-1	linoleate 9S-lipoxygenase-4	Glycine max	51-63
9522277-1	1998	A hypothesis that lipoxygenase may mediate N-dealkylation of xenobiotics was investigated using the prototype drug aminopyrine and soybean lipoxygenase as a model enzyme in the presence of hydrogen peroxide.	Nitrogen	43-44	linoleate 9S-lipoxygenase-4	Glycine max	18-30
9426211-2	1997	When synthesised in Escherichia coli more than 30% of the intact mature beta-lactamase-glycophorin C molecules assembled N-out, C-in into the cytoplasmic membrane.	Nitrogen	121-122	glycophorin C (Gerbich blood group)	Homo sapiens	87-100
12087059-6	2002	Unlike the wild-type receptor, which was associated with the caveolae, nonglycosylated N30D-Edg-1 was dispersed broadly in the membrane fractions separated by sucrose density gradient centrifugation, suggesting that internalization and microdomain localization of N-glycosylated Edg-1 might be related.	Nitrogen	87-88	sphingosine-1-phosphate receptor 1	Homo sapiens	91-97
12087059-6	2002	Unlike the wild-type receptor, which was associated with the caveolae, nonglycosylated N30D-Edg-1 was dispersed broadly in the membrane fractions separated by sucrose density gradient centrifugation, suggesting that internalization and microdomain localization of N-glycosylated Edg-1 might be related.	Nitrogen	87-88	sphingosine-1-phosphate receptor 1	Homo sapiens	92-97
12087059-7	2002	Although the precise molecular mechanism of the internalization of the N-glycosylated Edg-1 localized in the microdomain remains to be examined, the present study suggested that the presence of N-linked glycan in the receptor may play a regulatory role in the receptor dynamics in ligand-stimulated mammalian cells.	Nitrogen	71-72	sphingosine-1-phosphate receptor 1	Homo sapiens	86-91
12072497-8	2002	Sequence analysis of the V1/V2 and V3 regions of the viral envelope protein gp120 revealed that the more efficient CXCR4 usage of the later isolate might be caused by an additional potential N-glycosylation site in the V1/V2 loop.	Nitrogen	191-192	C-X-C motif chemokine receptor 4	Homo sapiens	115-120
12049627-11	2002	It is concluded that (a) the 92-kDa band detected in untransfected H4-IIE and ASM cells corresponds to the N-glycosylated beta-isoform of endogenous TRP-1, (b) the combined immunoprecipitation and Western-blot approach, employing two different antibodies, provides a reliable and specific procedure for detecting endogenous TRP-1 proteins, and (c) that caution is required in developing and utilizing anti-(TRP-1) antibodies.	Nitrogen	107-108	transient receptor potential cation channel, subfamily C, member 1	Rattus norvegicus	149-154
9428684-4	1997	hAPLP1 synthesized in a cell-free system displays an apparent molecular mass of approximately 80 kDa in SDS-containing gels and becomes N-glycosylated when the in vitro translation is performed in the presence of microsomes.	Nitrogen	136-137	amyloid beta precursor like protein 1	Homo sapiens	0-6
17199367-1	2006	Depending on each nitrogen atom of adenine molecule to which a silver atom of a metallic tip approaches, tip-enhanced near-field Raman spectroscopy may show a potential to achieve atomic site-selective detection sensitivity.	Nitrogen	18-26	TOR signaling pathway regulator	Homo sapiens	105-108
9401045-8	1997	Definition of this oruR locus and its effects upon OAcT activity provide evidence that control of ornithine levels in P. aeruginosa may have a significant impact upon how the cell is able to monitor and regulate the use of arginine and glutamate as sources of either carbon or nitrogen.	Nitrogen	277-285	ornithine utilization transcriptional regulator OruR	Pseudomonas aeruginosa PAO1	19-23
12034574-0	2002	Porcine surfactant protein D is N-glycosylated in its carbohydrate recognition domain and is assembled into differently charged oligomers.	Nitrogen	32-33	surfactant protein D	Homo sapiens	8-28
17173447-4	2006	The pKa* values of the pyridine nitrogens of the ligands are low (azpy 2.47, azpy-OH 3.06 and azpy-NMe2 4.60), suggesting that they are weak sigma-donors.	Nitrogen	32-41	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	99-103
12222688-7	2002	The enzymatic activities for N-acetylation of two arylamine carcinogens (2-aminofluorene, 4-aminobiphenyl), and a sulfonamide drug (sulfamethazine) were over 100-fold lower for NAT2 19 compared to reference NAT2 4.	Nitrogen	29-30	N-acetyltransferase 2	Homo sapiens	177-181
12222688-7	2002	The enzymatic activities for N-acetylation of two arylamine carcinogens (2-aminofluorene, 4-aminobiphenyl), and a sulfonamide drug (sulfamethazine) were over 100-fold lower for NAT2 19 compared to reference NAT2 4.	Nitrogen	29-30	N-acetyltransferase 2	Homo sapiens	207-211
11877405-11	2002	Collectively, our results demonstrate that: 1) MPO and EPO contribute to tyrosine nitration in vivo; 2) the major reactive nitrogen species formed by leukocyte peroxidase-catalyzed oxidation of NO(2)(-) is the one-electron oxidation product, (*)NO(2); 3) as a minor reaction, peroxidases may also catalyze the two-electron oxidation of NO(2)(-), producing a ONOO(-)-like product.	Nitrogen	123-131	myeloperoxidase	Mus musculus	47-50
9348299-5	1997	The extracellular Thr49 to Ile substitution abrogates one N-glycosylation site in the naturally occurring BALB/c IL-4R as well as in the experimentally point mutated C57BL/6-T49I sIL-4R, and both molecules display a nearly threefold reduction in IL-4-neutralizing activity compared to the C57BL/6 sIL-4R.	Nitrogen	58-59	interleukin 4 receptor, alpha	Mus musculus	113-118
9427410-4	1997	elm1-15 trp1 cells cannot use many nitrogen sources, are sensitive to amino acid analogues, have very low general amino acid permease activity and do not accumulate trehalose.	Nitrogen	35-43	serine/threonine protein kinase ELM1	Saccharomyces cerevisiae S288C	0-4
17168610-2	2006	It was found that for N-protected indoles the reaction proceeded smoothly in the presence of 5 mol % of Pd(acac)2 and 10 mol % of PPh3 at 80 degrees C in HOAc, while for N-unprotected indoles, the reaction was carried out by using 5 mol % of Pd(dba)2 or 2.5 mol % of Pd2(dba)3.CHCl3 with 10 mol % of 2,2"-bipyridine as the catalyst in toluene.	Nitrogen	22-23	PAF1 homolog, Paf1/RNA polymerase II complex component	Homo sapiens	267-270
9276881-7	1997	Feeding T-2 toxin decreased serum cholesterol, total protein, urea nitrogen, and mean corpuscular volume; however, only cholesterol and mean corpuscular volume were improved with the addition of SAC (Experiment 1).	Nitrogen	67-75	solute carrier family 25 member 5	Homo sapiens	8-11
9299393-1	1997	The role of the N-myristoylation of the human immunodeficiency virus type 1 (HIV-1) gag protein in ACH-2 cells was studied.	Nitrogen	16-17	acyl-CoA thioesterase 1	Homo sapiens	99-104
11996583-1	2002	Upon photochemical nitrogen extrusion, azoalkane 1b yields the diastereomeric housane products syn-2b (inversion) and anti-2b (retention), whose syn-to-anti isomerization (k(iso)) is observable already at room temperature.	Nitrogen	19-27	synemin	Homo sapiens	95-98
11996583-1	2002	Upon photochemical nitrogen extrusion, azoalkane 1b yields the diastereomeric housane products syn-2b (inversion) and anti-2b (retention), whose syn-to-anti isomerization (k(iso)) is observable already at room temperature.	Nitrogen	19-27	synemin	Homo sapiens	145-148
12016157-3	2002	This study examined the urinary excretion of N(2)-(beta-1-glucos-iduronyl)-2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine-the major human urinary N-oxidation metabolite of PhIP-and determined its relationship to individual activity levels of cytochrome P4501A2 (CYP1A2) and N-acetyltransferase (NAT2).	Nitrogen	45-46	N-acetyltransferase 2	Homo sapiens	303-307
17168610-2	2006	It was found that for N-protected indoles the reaction proceeded smoothly in the presence of 5 mol % of Pd(acac)2 and 10 mol % of PPh3 at 80 degrees C in HOAc, while for N-unprotected indoles, the reaction was carried out by using 5 mol % of Pd(dba)2 or 2.5 mol % of Pd2(dba)3.CHCl3 with 10 mol % of 2,2"-bipyridine as the catalyst in toluene.	Nitrogen	170-171	PAF1 homolog, Paf1/RNA polymerase II complex component	Homo sapiens	267-270
17015441-5	2006	We identified two potential N-linked glycosylation sites in TRPM8 (Asn-821 and Asn-934) and mutated them to show that only the site in the putative pore region at position 934 is modified and that glycosylation of this site is not absolutely necessary for cell surface expression or responsiveness to icilin, menthol, and cool temperatures.	Nitrogen	28-29	transient receptor potential cation channel subfamily M member 8	Cricetulus griseus	60-65
11914074-2	2002	We found that the alpha(1B)-AR undergoes N-linked glycosylation as demonstrated by its sensitivity to endoglycosidases and by the effect of tunicamycin on receptor maturation.	Nitrogen	41-42	adrenoceptor alpha 1B	Homo sapiens	28-30
11914074-3	2002	Pulse-chase labeling experiments in BHK-21 cells demonstrate that the alpha(1B)-AR is synthesized as a 70 kDa core glycosylated precursor that is converted to the 90 kDa mature form of the receptor with a half-time of approximately 2 h. N-Linked glycosylation of the alpha(1B)-AR occurs at four asparagines on the N-terminus of the receptor.	Nitrogen	237-238	adrenoceptor alpha 1B	Homo sapiens	80-82
11914074-6	2002	Our findings demonstrate that N-linked glycosylation and phosphorylation, but not palmitoylation or O-linked glycosylation, contribute to the structural heterogeneity of the alpha(1B)-AR as it is observed in SDS-PAGE.	Nitrogen	30-31	adrenoceptor alpha 1B	Homo sapiens	184-186
11836118-5	2002	It was also found that the substitution pattern on the 5-benzylidene moiety markedly influenced the activity of N-unsubstituted 2,4-thiazolidinediones 2, compounds with substituents at the meta position being generally more effective than the para-substituted ones; however, this SAR was not evidenced in acetates 3 and acids 4.	Nitrogen	112-113	sarcosine dehydrogenase	Homo sapiens	280-283
11863451-11	2002	Removal of chylomicron-sized n-6 TG emulsions is modulated by lipoprotein lipase (LPL), apoE, LDL-R, and lactoferrin-sensitive pathways.	Nitrogen	21-22	lipoprotein lipase	Mus musculus	62-80
11863451-11	2002	Removal of chylomicron-sized n-6 TG emulsions is modulated by lipoprotein lipase (LPL), apoE, LDL-R, and lactoferrin-sensitive pathways.	Nitrogen	21-22	lipoprotein lipase	Mus musculus	82-85
11863451-11	2002	Removal of chylomicron-sized n-6 TG emulsions is modulated by lipoprotein lipase (LPL), apoE, LDL-R, and lactoferrin-sensitive pathways.	Nitrogen	21-22	low density lipoprotein receptor	Mus musculus	94-99
11904149-1	2002	The yeast high-affinity glucose transporters Hxt6p and Hxt7p are rapidly degraded during nitrogen starvation in the presence of high concentrations of fermentable carbon sources.	Nitrogen	89-97	hexose transporter HXT6	Saccharomyces cerevisiae S288C	45-50
11856327-11	2002	On removal of N-glycans from rpro-Der p 1, which harbours two putative N-glycosylation sites in both propeptide and mature sequence, the mature rDer p 1 appeared.	Nitrogen	14-15	crystallin gamma F, pseudogene	Homo sapiens	38-41
11856327-11	2002	On removal of N-glycans from rpro-Der p 1, which harbours two putative N-glycosylation sites in both propeptide and mature sequence, the mature rDer p 1 appeared.	Nitrogen	14-15	crystallin gamma F, pseudogene	Homo sapiens	149-152
15481768-10	1997	It can be concluded that in diet-obese animals the mechanisms involved in retaining nitrogen (low CPS activity) are modulated at the post-translational level.	Nitrogen	84-92	carbamoyl-phosphate synthase 1	Rattus norvegicus	98-101
15481771-10	1997	Furthermore, total nitrogen remained unchanged in these animals and they showed an increased activity in alanine aminotransferase and glutamine synthetase.	Nitrogen	19-27	glutamate-ammonia ligase	Rattus norvegicus	134-154
9245835-1	1997	Nodule-specific uricase (uricase II) is a homotetramer of a 33-kDa polypeptide, nodulin 35, and plays a key role in the assimilation of nitrogen fixed by microsymbionts in most legumes that have determinate nodules.	Nitrogen	136-144	uricase-2 isozyme 2	Glycine max	80-90
9223432-0	1997	How important is the N-3 sugar moiety in the tight-binding interaction of coformycin with adenosine deaminase?	Nitrogen	21-22	adenosine deaminase	Homo sapiens	90-109
9223432-1	1997	Preliminary findings on the possible important role of the N-3 sugar moiety of coformycin in its tight-binding interaction with adenosine deaminase (ADA) are reported.	Nitrogen	59-60	adenosine deaminase	Homo sapiens	128-147
9223432-1	1997	Preliminary findings on the possible important role of the N-3 sugar moiety of coformycin in its tight-binding interaction with adenosine deaminase (ADA) are reported.	Nitrogen	59-60	adenosine deaminase	Homo sapiens	149-152
9377092-3	1997	In this paper we summarize our efforts to exploit this metabolic pathway to develop latent nitrogen mustard derivatives related to the oxazaphosphorine antitumor agent cyclophosphamide which may target MAO-A and/or MAO-B rich cells.	Nitrogen	91-99	monoamine oxidase B	Homo sapiens	215-220
9218873-1	1997	In this study, the regulatory elements involved in ICAM-1 transcriptional response to phorbol ester (12-0-tetradecanoylphorbol-13-acetate; TPA) have been investigated in the human neuroblastoma cell line, SK-N-SH.	Nitrogen	208-209	intercellular adhesion molecule 1	Homo sapiens	51-57
17015442-0	2006	Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain.	Nitrogen	72-80	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	25-29
9171383-1	1997	Nitrogen catabolic gene expression in Saccharomyces cerevisiae has been reported to be regulated by three GATA family proteins, the positive regulators Gln3p and Gat1p/Nil1p and the negative regulator Dal80p/Uga43p.	Nitrogen	0-8	Dal80p	Saccharomyces cerevisiae S288C	201-207
11773509-1	2002	Somatotropin (ST) treatment promotes animal growth and allows for the conservation of amino acids by increasing nitrogen retention and reducing ureagenesis and amino acid oxidation.	Nitrogen	112-120	somatotropin	Sus scrofa	0-12
9171383-1	1997	Nitrogen catabolic gene expression in Saccharomyces cerevisiae has been reported to be regulated by three GATA family proteins, the positive regulators Gln3p and Gat1p/Nil1p and the negative regulator Dal80p/Uga43p.	Nitrogen	0-8	Dal80p	Saccharomyces cerevisiae S288C	208-214
17015442-0	2006	Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain.	Nitrogen	137-145	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	102-106
9171383-2	1997	We show here that a fourth member of the yeast GATA family, the Dal80p homolog Deh1p, also negatively regulates expression of some, but not all, nitrogen catabolic genes, i.e., GAP1, DAL80, and UGA4 expression increases in a deh1 delta mutant.	Nitrogen	145-153	Dal80p	Saccharomyces cerevisiae S288C	64-70
9171383-2	1997	We show here that a fourth member of the yeast GATA family, the Dal80p homolog Deh1p, also negatively regulates expression of some, but not all, nitrogen catabolic genes, i.e., GAP1, DAL80, and UGA4 expression increases in a deh1 delta mutant.	Nitrogen	145-153	Dal80p	Saccharomyces cerevisiae S288C	183-188
11577085-11	2001	Heparan sulfate chains of glypican-1 were either cleaved with heparanase at sites embracing the highly modified regions or with nitrite at N-unsubstituted glucosamine residues.	Nitrogen	139-140	glypican 1	Homo sapiens	26-36
17015442-0	2006	Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain.	Nitrogen	137-145	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	169-173
17015442-1	2006	Tor1,2 control of type 2A-related phosphatase activities in Saccharomyces cerevisiae has been reported to be responsible for the regulation of Gln3 phosphorylation and intracellular localization in response to the nature of the nitrogen source available.	Nitrogen	228-236	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	143-147
11739012-13	2001	In conclusion, dietary PUFA intake can inhibit PG production in bovine endometrial explants, with a more pronounced effect following n-6 rather than n-3 supplementation.	Nitrogen	1-2	PUFA	Bos taurus	23-27
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	139-147	melanocortin 5 receptor	Homo sapiens	149-152
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	139-147	melanocortin 5 receptor	Homo sapiens	307-310
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	245-253	melanocortin 5 receptor	Homo sapiens	149-152
11765789-2	2001	Absorption, fluorescence excitation and fluorescence spectra have revealed that the monocation (MC) of DMAPPI, protonated at the imidazole nitrogen (MC2) (Scheme 2) is present in the S0 state at w0 = 0, along with the MC, protonated at pyridine nitrogen (MC3) and only normal emission is observed from both MC2 and MC3.	Nitrogen	245-253	melanocortin 5 receptor	Homo sapiens	307-310
9190854-10	1997	Our human liver microsomal study using the near-therapeutic IMI concentration (2 microM) suggests that 1) CYP2C19 and 1A2 are involved in the N-demethylation and the 2-hydroxylation is mediated exclusively by CYP2D6 and partially by CYP2C19 in the EM livers, and 2) CYP1A2 and 2D6 play a major role in IMI N-demethylation and 2-hydroxylation, respectively, in the PM livers.	Nitrogen	142-143	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	106-121
9190854-10	1997	Our human liver microsomal study using the near-therapeutic IMI concentration (2 microM) suggests that 1) CYP2C19 and 1A2 are involved in the N-demethylation and the 2-hydroxylation is mediated exclusively by CYP2D6 and partially by CYP2C19 in the EM livers, and 2) CYP1A2 and 2D6 play a major role in IMI N-demethylation and 2-hydroxylation, respectively, in the PM livers.	Nitrogen	142-143	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	106-113
9190854-10	1997	Our human liver microsomal study using the near-therapeutic IMI concentration (2 microM) suggests that 1) CYP2C19 and 1A2 are involved in the N-demethylation and the 2-hydroxylation is mediated exclusively by CYP2D6 and partially by CYP2C19 in the EM livers, and 2) CYP1A2 and 2D6 play a major role in IMI N-demethylation and 2-hydroxylation, respectively, in the PM livers.	Nitrogen	306-307	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	106-121
9190854-10	1997	Our human liver microsomal study using the near-therapeutic IMI concentration (2 microM) suggests that 1) CYP2C19 and 1A2 are involved in the N-demethylation and the 2-hydroxylation is mediated exclusively by CYP2D6 and partially by CYP2C19 in the EM livers, and 2) CYP1A2 and 2D6 play a major role in IMI N-demethylation and 2-hydroxylation, respectively, in the PM livers.	Nitrogen	306-307	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	106-113
9210297-5	1997	This is a linear fragment of the disialylated tetrasaccharide sequence Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-found in the milk oligosaccharide disialyl LNT (the GlcNAc residue of the tetrasaccharide linked to lactose) and also of N-linked chains (GlcNAc linked to Man).	Nitrogen	71-72	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	92-98
9210297-5	1997	This is a linear fragment of the disialylated tetrasaccharide sequence Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-found in the milk oligosaccharide disialyl LNT (the GlcNAc residue of the tetrasaccharide linked to lactose) and also of N-linked chains (GlcNAc linked to Man).	Nitrogen	71-72	immunoglobulin binding protein 1	Homo sapiens	109-118
9210297-5	1997	This is a linear fragment of the disialylated tetrasaccharide sequence Neu5Ac(alpha 2-3)Gal(beta 1-3)[Neu5Ac(alpha 2-6)]GlcNAc(beta 1-found in the milk oligosaccharide disialyl LNT (the GlcNAc residue of the tetrasaccharide linked to lactose) and also of N-linked chains (GlcNAc linked to Man).	Nitrogen	71-72	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	127-133
17015442-2	2006	According to the model, excess nitrogen stimulates Tor1,2 to phosphorylate Tip41 and/or Tap42.	Nitrogen	31-39	Tap42p	Saccharomyces cerevisiae S288C	88-93
17015442-5	2006	When Tor1,2 kinase activities are inhibited by limiting nitrogen, or rapamycin-treatment, Tap42 can no longer complex with Sit4.	Nitrogen	56-64	Tap42p	Saccharomyces cerevisiae S288C	90-95
9144178-10	1997	The demonstration that DAD1 is a subunit of the OST suggests that induction of a cell death pathway upon loss of DAD1 in the tsBN7 cell line reflects the essential nature of N-linked glycosylation in eukaryotes.	Nitrogen	128-129	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	Mesocricetus auratus	23-27
11604271-1	2001	We found that N-acetylation polymorphism can be evaluated from the disposition kinetics of sulfapyridine (SP) and 5-aminosalicylic acid (5-ASA) and their acetylated metabolites generated by N-acetyltransferase (NAT2) after oral administration of salicylazosulfapyridine (SASP).	Nitrogen	14-15	N-acetyltransferase 2	Homo sapiens	211-215
17015442-8	2006	We found that Sit4 actively brought about Gln3-Myc(13) dephosphorylation in both good (glutamine or ammonia) and poor (proline) nitrogen sources.	Nitrogen	128-136	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	14-18
17015442-8	2006	We found that Sit4 actively brought about Gln3-Myc(13) dephosphorylation in both good (glutamine or ammonia) and poor (proline) nitrogen sources.	Nitrogen	128-136	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
11606127-9	2001	However, as CYP 2C8 and 2C18, CYP 2C19 showed a much better affinity for neutral compounds derived from N-alkylation of SPA and for anionic compounds bearing a larger R(1) substituent.	Nitrogen	104-105	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	30-38
17015442-9	2006	This Sit4 activity masked nitrogen source-dependent changes in Gln3-Myc(13) phosphorylation which were clearly visible when SIT4 was deleted.	Nitrogen	26-34	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	5-9
11606127-9	2001	However, as CYP 2C8 and 2C18, CYP 2C19 showed a much better affinity for neutral compounds derived from N-alkylation of SPA and for anionic compounds bearing a larger R(1) substituent.	Nitrogen	104-105	surfactant protein A2	Homo sapiens	120-123
9208105-6	1997	These results combined with previous SAR data underline the crucial importance of the D-ring in eudistomins as a scaffold for the correct positioning of both basic nitrogen atoms.	Nitrogen	164-172	sarcosine dehydrogenase	Homo sapiens	37-40
17015442-9	2006	This Sit4 activity masked nitrogen source-dependent changes in Gln3-Myc(13) phosphorylation which were clearly visible when SIT4 was deleted.	Nitrogen	26-34	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	63-67
17015442-9	2006	This Sit4 activity masked nitrogen source-dependent changes in Gln3-Myc(13) phosphorylation which were clearly visible when SIT4 was deleted.	Nitrogen	26-34	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	124-128
9112387-9	1997	These results demonstrate that N-linked glycosylation is required for normal expression of the hCaR at the cell surface.	Nitrogen	31-32	CXADR Ig-like cell adhesion molecule	Homo sapiens	95-99
9223227-5	1997	An N-glycosylation site and five cysteine residues conserved in human, murine and rabbit IL-1ras were also found at the corresponding positions in equine IL-1ra.	Nitrogen	3-4	interleukin 1 receptor antagonist	Equus caballus	89-95
11500500-4	2001	The formation of the high affinity complex required Arg-142, Lys-143, Arg-145, Lys-146, and Arg-147 from apoE and N- and 6-O-sulfo groups of the glucosamine units from the heparin fragment.	Nitrogen	114-115	DEAH-box helicase 40	Homo sapiens	92-99
11477102-8	2001	IL-18-induced adhesion molecule expression appears to be mediated through nuclear factor kappa B (NF kappa B) and phosphatidyl-inositol 3 kinase (PI 3-kinase) since addition of inhibitors to either NF kappa B (pyrrolidine dithiocarbamate and N-acetyl-l-cysteine) or PI 3-kinase (LY294002) inhibited RA synovial fibroblast VCAM-1 expression by 50 to 60%.	Nitrogen	98-99	interleukin 18	Homo sapiens	0-5
17015442-10	2006	The extent of Sit4 requirement for Gln3 nuclear localization was both nitrogen source- and strain-dependent.	Nitrogen	70-78	type 2A-related serine/threonine-protein phosphatase SIT4	Saccharomyces cerevisiae S288C	14-18
17015442-10	2006	The extent of Sit4 requirement for Gln3 nuclear localization was both nitrogen source- and strain-dependent.	Nitrogen	70-78	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	35-39
17121544-0	2006	Fission yeast Tor2 links nitrogen signals to cell proliferation and acts downstream of the Rheb GTPase.	Nitrogen	25-33	phosphatidylinositol kinase-related protein kinase TOR2	Saccharomyces cerevisiae S288C	14-18
11679080-8	2001	Additionally, the proper transcription of several nitrogen-regulated genes, including NIL1 and DAL80, encoding well-studied GATA transcription factors, is dependent upon Ssy1p.	Nitrogen	50-58	Dal80p	Saccharomyces cerevisiae S288C	95-100
11679080-8	2001	Additionally, the proper transcription of several nitrogen-regulated genes, including NIL1 and DAL80, encoding well-studied GATA transcription factors, is dependent upon Ssy1p.	Nitrogen	50-58	Ssy1p	Saccharomyces cerevisiae S288C	170-175
9102228-11	1997	Inhibition of N-linked glycosylation with tunicamycin resulted in decreased HA binding of cells bearing an active CD44 receptor.	Nitrogen	14-15	CD44 molecule (Indian blood group)	Homo sapiens	114-118
9161026-0	1997	Nitrite reductase expression is regulated at the post-transcriptional level by the nitrogen source in Nicotiana plumbaginifolia and Arabidopsis thaliana.	Nitrogen	83-91	nitrite reductase 1	Arabidopsis thaliana	0-17
11554819-1	2001	(4S)-tert-Butyl 2,2-dioxo-3-PhF-1,2,3-oxathiazainane-4-carboxylate reacted effectively with nitrogen, sulfur, and oxygen nucleophiles to provide enantiopure (&gt;97% ee) gamma-substituted alpha-amino acids.	Nitrogen	92-100	PHD finger protein 1	Homo sapiens	28-33
9161026-5	1997	When these plants were grown in vitro on media containing either nitrate or ammonium as sole nitrogen source, NiR mRNA derived from transgene expression was constitutively expressed, whereas NiR activity and protein level were strongly reduced on ammonium-containing medium.	Nitrogen	93-101	nitrite reductase 1	Arabidopsis thaliana	110-113
17121544-6	2006	Remarkably, we have found that tor2(ts) mimics nitrogen starvation responses, because the mutant displays a number of phenotypes that are normally induced only on nitrogen deprivation.	Nitrogen	47-55	phosphatidylinositol kinase-related protein kinase TOR2	Saccharomyces cerevisiae S288C	31-35
9106207-2	1997	Another GATA factor, Uga43p/Dal80p, downregulates to varying degrees the expression of some nitrogen-regulated genes.	Nitrogen	92-100	Dal80p	Saccharomyces cerevisiae S288C	21-27
9106207-2	1997	Another GATA factor, Uga43p/Dal80p, downregulates to varying degrees the expression of some nitrogen-regulated genes.	Nitrogen	92-100	Dal80p	Saccharomyces cerevisiae S288C	28-34
17121544-6	2006	Remarkably, we have found that tor2(ts) mimics nitrogen starvation responses, because the mutant displays a number of phenotypes that are normally induced only on nitrogen deprivation.	Nitrogen	163-171	phosphatidylinositol kinase-related protein kinase TOR2	Saccharomyces cerevisiae S288C	31-35
9106207-6	1997	While Uga43p is active specifically under nitrogen-depression conditions, Gzf3p exerts its negative regulatory function specifically on preferred nitrogen sources: It is involved in nitrogen repression of Nil1p-dependent transcription.	Nitrogen	42-50	Dal80p	Saccharomyces cerevisiae S288C	6-12
16988941-3	2006	Although it is generally accepted that ABP is metabolically activated via N-hydroxylation by CYP1A2 in human liver, previous studies using Cyp1a2-null mice indicated the involvement of other enzyme(s).	Nitrogen	74-75	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	93-99
9020858-5	1997	Differences between the immunoreactivity of KAP/BAP and LAP with a BAP antibody were mainly attributed to the N-glycosylated moieties of the TNAPs.	Nitrogen	110-111	cyclin dependent kinase inhibitor 3	Homo sapiens	44-47
9020859-13	1997	A slightly higher apparent molecular mass of the monomeric form and N-terminal chain of bone TRAP compared with the recombinant enzyme could not be accounted for by differential N-glycosylation.	Nitrogen	68-69	acid phosphatase 5, tartrate resistant	Rattus norvegicus	93-97
11536167-7	2001	Site-directed mutagenesis of each of seven potential N-glycosylation sites showed that four sites were required to generate forms of tyrosinase that could be recognized by individual T cell clones.	Nitrogen	53-54	tyrosinase	Homo sapiens	133-143
17065563-5	2006	IEF of plasma ApoC-III protein, introduced O-glycosylation defects that delineated some new CDGs due to mutations of both N- and O-glycosylation.	Nitrogen	122-123	apolipoprotein C3	Homo sapiens	14-22
11520063-1	2001	We investigated the regulation of PKC activity by reactive nitrogen species in order to examine whether such species regulate PKC in neurons.	Nitrogen	59-67	protein kinase C, alpha	Rattus norvegicus	34-37
8992988-0	1997	Elimination of N-linked glycosylation sites from the human IgA1 constant region: effects on structure and function.	Nitrogen	15-16	immunoglobulin heavy constant alpha 1	Homo sapiens	59-63
8992988-1	1997	IgA1 Abs possess conserved N-linked glycosylation sites in the second C region and secreted tailpiece domains.	Nitrogen	27-28	immunoglobulin heavy constant alpha 1	Homo sapiens	0-4
8992988-9	1997	These studies demonstrate that N-linked glycosylation in the constant domain of human IgA1 plays an important role in the biologic properties of IgA1.	Nitrogen	31-32	immunoglobulin heavy constant alpha 1	Homo sapiens	86-90
8992988-9	1997	These studies demonstrate that N-linked glycosylation in the constant domain of human IgA1 plays an important role in the biologic properties of IgA1.	Nitrogen	31-32	immunoglobulin heavy constant alpha 1	Homo sapiens	145-149
11511107-0	2001	Tissue-specific N-glycosylation of the ClC-3 chloride channel.	Nitrogen	16-17	chloride voltage-gated channel 3	Rattus norvegicus	39-44
16860002-8	2006	Finally, in an assay for inactivating mutations, FANCD2 mutants have an elevated mutation rate in response to nitrogen mustard, indicating that these flies are hypermutable.	Nitrogen	110-118	Fancd2	Drosophila melanogaster	49-55
11356843-9	2001	CAN1, DAL4, DAL5, MEP2, DAL1, DAL80, and GDH3 transcription is down-regulated by Vid30p function with proline as the nitrogen source.	Nitrogen	117-125	arginine permease CAN1	Saccharomyces cerevisiae S288C	0-4
8900102-1	1996	Aspergillus fumigatus can utilize chicken feather keratin as its sole carbon and nitrogen source.	Nitrogen	81-89	keratin	Gallus gallus	50-57
16751172-10	2006	In addition to the well-established roles of PPARalpha, we propose a novel function of PPARalpha in the small intestine, that is, the regulation of nitrogen absorption through PEPT1 during fasting.	Nitrogen	148-156	peroxisome proliferator activated receptor alpha	Rattus norvegicus	87-96
8900102-5	1996	Secretion of keratin-hydrolyzing activity in A. fumigatus was induced by keratin but repressed by low-molecular-weight carbon and nitrogen sources.	Nitrogen	130-138	keratin	Gallus gallus	13-20
8985785-2	1996	Alanine and N-methylation scans together with molecular modelling were implemented in order to propose a binding conformation of the minimum active fragment of bombesin (BB), Ac-BB[7-14], to the gastrin releasing peptide (GRP) and neuromedin B (NMB) receptors.	Nitrogen	12-13	gastrin releasing peptide	Homo sapiens	160-168
8985785-2	1996	Alanine and N-methylation scans together with molecular modelling were implemented in order to propose a binding conformation of the minimum active fragment of bombesin (BB), Ac-BB[7-14], to the gastrin releasing peptide (GRP) and neuromedin B (NMB) receptors.	Nitrogen	12-13	gastrin releasing peptide	Homo sapiens	170-172
11368881-1	2001	We examined the effects of the monoclonal antibody against the type I insulin-like growth factor receptor (IGF-IR), alphaIR3, on cell growth and membrane glutamine (Gln) transport in a human neuroblastoma cell line, SK-N-SH.	Nitrogen	219-220	insulin like growth factor 1 receptor	Homo sapiens	107-113
12702356-7	2001	A few genes, FSP2, RGS2, AQY1, YFL030W, were expressed more strongly with nitrogen limitation as compared to other conditions.	Nitrogen	74-82	Aqy1p	Saccharomyces cerevisiae S288C	25-29
11396966-3	2001	Coexpression of cytochrome b(5) enhanced LAAM N-demethylation, most dramatically for 3A4, but had marginal effects on norLAAM N-demethylation.	Nitrogen	46-47	mitochondrially encoded cytochrome b	Homo sapiens	16-28
9007688-9	1996	The critical structural feature for selectivity between the alpha 1A and alpha 1B adrenergic receptor sites is the distance between the basic nitrogen atom and the centre of an aromatic ring system.	Nitrogen	142-150	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	60-68
16751172-10	2006	In addition to the well-established roles of PPARalpha, we propose a novel function of PPARalpha in the small intestine, that is, the regulation of nitrogen absorption through PEPT1 during fasting.	Nitrogen	148-156	solute carrier family 15 member 1	Rattus norvegicus	176-181
9007688-9	1996	The critical structural feature for selectivity between the alpha 1A and alpha 1B adrenergic receptor sites is the distance between the basic nitrogen atom and the centre of an aromatic ring system.	Nitrogen	142-150	adrenoceptor alpha 1B	Homo sapiens	73-101
16899296-8	2006	The protonated amino groups of OSpm are involved in non-covalent interaction with the nitrogen atoms N(1), N(7) or N(3) of the purine or pyrimidine ring, whereas at higher pH, deprotonated nitrogen atoms of polyamine are engaged in metallation in MLL" species.	Nitrogen	86-94	lysine methyltransferase 2A	Homo sapiens	247-250
8939925-4	1996	Treatment of adipocytes with linoleic (18:2, n-6) and linolenic (18:3, n-3) acids also resulted in inhibition of scd1 mRNA accumulation.	Nitrogen	43-47	stearoyl-CoA desaturase	Homo sapiens	113-117
11278778-0	2001	The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum.	Nitrogen	84-85	alpha-1,2-mannosyltransferase ALG11	Saccharomyces cerevisiae S288C	10-15
16899296-8	2006	The protonated amino groups of OSpm are involved in non-covalent interaction with the nitrogen atoms N(1), N(7) or N(3) of the purine or pyrimidine ring, whereas at higher pH, deprotonated nitrogen atoms of polyamine are engaged in metallation in MLL" species.	Nitrogen	189-197	lysine methyltransferase 2A	Homo sapiens	247-250
11393703-1	2001	Rat liver microsomal and lysosomal beta-glucuronidase-derived glycopeptides were obtained by extensive Pronase digestion followed by N-[14C]acetylation and desialylation by neuraminidase treatment.	Nitrogen	133-134	glucuronidase, beta	Rattus norvegicus	35-53
16777210-0	2006	Zygote donor nitrogen metabolism and in vitro embryo culture perturbs in utero development and IGF2R expression in ovine fetal tissues.	Nitrogen	13-21	insulin like growth factor 2 receptor	Homo sapiens	95-100
11290523-5	2001	Furthermore, a cell-permeable N-myristoylated synthetic filamin peptide (containing the COOH-terminal CaM kinase II phosphorylation site) attenuated both thrombin-induced filamin phosphorylation and decreases in TER.	Nitrogen	30-31	coagulation factor II, thrombin	Bos taurus	154-162
8910433-6	1996	Furthermore, the CYP2D18-expressed COS cell lysate showed N-demethylation activity toward imipramine, whereas another brain P-450 CYP4F6-expressed COS cell lysate showed 10-hydroxylation activity.	Nitrogen	58-59	cytochrome P450, family 2, subfamily d, polypeptide 4	Rattus norvegicus	17-24
11372865-1	2001	The effect of oxygen-nitrogen atmosphere (N2 + 10%O2, N2 + 1%O2 and 99.999% N2) on the formation of PCB, PCDD and PCDF by the de novo synthetic reactions in the system consisting of extracted fly ash (from municipal waste incinerators--MWI), activated carbon, CuCl2 x 2H2O and NaCl at 340 degrees C was studied.	Nitrogen	54-56	Pyruvate carboxylase	Drosophila melanogaster	100-103
8897649-2	1996	Breathing a gas mixture with elevated CO2 (15% CO2, 21% O2 and 64% N2, or 15% CO2 balance O2) for 60 min, induced activation of the c-fos gene in widespread regions of the CNS, as indicated by the expression of Fos-like immunoreactive protein (Fos).	Nitrogen	67-69	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	132-137
11372865-5	2001	Formation of nonortho PCB was relatively high compared to the system where only nitrogen was present.	Nitrogen	80-88	Pyruvate carboxylase	Drosophila melanogaster	22-25
16865752-2	2006	The exo-NH(2)R group of the azanonaborane of the type [(RH(2)N)B(8)H(11)NHR] can be exchanged by one hetero-nitrogen atom of the imidazole ring.	Nitrogen	108-116	5'-3' exoribonuclease 1	Mus musculus	4-7
11401708-8	2001	After the addition of glucose or of a nitrogen source to starved cells, Pph22-overexpressing cells showed a delayed exit from stationary phase, a delayed induction of ribosomal gene expression and constitutive repression of stress-regulated element-controlled genes.	Nitrogen	38-46	phosphoprotein phosphatase 2A catalytic subunit PPH22	Saccharomyces cerevisiae S288C	72-77
8755617-3	1996	To study uptake systems for mineral nitrogen, three genes homologous to Arabidopsis nitrate and ammonium transporters (AtNrt1 and AtAmt1) were isolated from a root hair-specific tomato cDNA library.	Nitrogen	36-44	nitrate transporter 1.1	Arabidopsis thaliana	119-125
16899466-10	2006	The mouse MT-CYP1A1 is an extrinsic membrane protein, which exhibited high FDX1 plus FDXR-mediated N-demethylation of a number of tricyclic antidepressants, pain killers, anti-psychotics, and narcotics that are poor substrates for microsomal CYP1A1.	Nitrogen	99-100	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	13-19
11450138-4	2001	N-type glycosylation of gp83 and gp78 was shown using tunicamicin.	Nitrogen	0-1	autocrine motility factor receptor	Homo sapiens	33-37
17002368-2	2006	These arise from fission of bond a, between the nitrogen (N-6) and C-1, and bond b, between C-4, with the two phenyl substituents, and C-5, adjacent to the nitrogen.	Nitrogen	156-164	complement C4A (Rodgers blood group)	Homo sapiens	92-95
11304143-4	2001	Further reaction of 1 with an excess of HAl(CMe3)2 yielded the tricyclic aluminum and nitrogen rich Al4N4 compound [(Me3C)2AlN2H2]2[Al(CMe3)2]2, 2, in which each N-N bond of a central six-membered Al2N4 ring similar to that of 1 is side-on-coordinated to an Al(CMe3)2 group.	Nitrogen	86-94	histidine ammonia-lyase	Homo sapiens	40-43
8757998-4	1996	Uncleaved gp 130 remained completely sensitive to endo-beta-N-acetylglucosaminidase H (Endo-H) in untreated cells following long chase periods, indicating high-mannose oligosaccharides at all of the 18 N-linked glycosylation sites (Asn-X-Ser/Thr) and retention in the endoplasmic reticulum.	Nitrogen	60-61	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	10-16
8735845-4	1996	In the series of N-protected tetrapeptides X30-Phg31-Asp32-Nal33-N(CH3)2, the Boc-substituent was shown to be optimal among the N-protecting groups Boc, 2Adoc, propionyl or acetyl when X = Trp.	Nitrogen	17-18	BOC cell adhesion associated, oncogene regulated	Rattus norvegicus	148-151
11666392-7	1996	The formation of the two diastereomers, syn and anti, was expected due to the configuration of the nitrogen substituent (R) with respect to the central TcO core.	Nitrogen	99-107	synemin	Homo sapiens	40-43
11312743-2	2001	Analysis of the electron paramagnetic resonance spectrum of 5 revealed significant spin density on the exocyclic nitrogen but very little spin density on the phosphorus, in contrast to the previously reported P-phenyl-6-phosphaverdazyl (4).	Nitrogen	113-121	spindlin 1	Homo sapiens	83-87
11312743-4	2001	The spin transfer to the dimethylamino group in 5 was revealed to arise from spiroconjugation-type overlap between the nitrogen 2p orbital with the verdazyl radical singly occupied molecular orbital.	Nitrogen	119-127	spindlin 1	Homo sapiens	4-8
11361134-7	2001	Therefore mutant proteins in which the N-glycosylation sites were eliminated (Asn --&gt; Gln in mouse MDR3 Pgp, Asn --&gt; Gln or Ala in human MDR1 Pgp) were expressed in P. pastoris and purified to homogeneity.	Nitrogen	39-40	phosphoglycolate phosphatase	Mus musculus	107-110
17002368-2	2006	These arise from fission of bond a, between the nitrogen (N-6) and C-1, and bond b, between C-4, with the two phenyl substituents, and C-5, adjacent to the nitrogen.	Nitrogen	156-164	complement C5	Homo sapiens	135-138
8901135-0	1996	Identification of the native NIT2 major nitrogen regulatory protein in nuclear extracts of Neurospora crassa.	Nitrogen	40-48	nitrilase family, member 2	Mus musculus	29-33
16942762-7	2006	We conclude that novel aCDase inhibitors can evolve from N-acylation of sphingoid bases with electron deficient-acyl groups.	Nitrogen	57-58	N-acylsphingosine amidohydrolase 1	Homo sapiens	23-29
8635486-5	1996	The PDGF-induced IGF-1R expression was suppressed in the presence of tunicamycin, an inhibitor of N-linked glycosylation.	Nitrogen	98-99	insulin like growth factor 1 receptor	Homo sapiens	17-23
11294895-9	2001	We also report that, when fission yeasts are challenged with nitrogen starvation, Spo20 translocates to the nucleus.	Nitrogen	61-69	Spo20p	Saccharomyces cerevisiae S288C	82-87
11277529-4	2001	The inactivity of the 8-oxygenated analogues seems to point out that, unlike cocaine and its analogues, interactions of benztropine ligands with DAT may be strongly governed by the nitrogen atom.	Nitrogen	181-189	solute carrier family 6 member 3	Homo sapiens	145-148
16984173-1	2006	The observation of proton to nitrogen-15 heteronuclear Overhauser effects in the microcrystalline protein Crh is used to confirm that the principal mechanism of relaxation of amide nitrogens is due to the fluctuation of the N-H dipolar couplings caused by N-H bond dynamics.	Nitrogen	29-37	corticotropin releasing hormone	Homo sapiens	106-109
11260159-10	2001	Polyamine oxidase shows only one N-glycosilation site whose carbohydrate moiety seems to be composed of a branched chain of seven ordered sugars, i.e. two N-acetyl-D-glucosamine-, three mannose-, one fucose- and one xylose-residues.	Nitrogen	33-34	polyamine oxidase	Homo sapiens	0-17
8610367-8	1996	Addition to IL-10-specific antibodies resulted in higher enhancement of INF-gamma (235 +/- 38% vs. 122 +/- 39%, P = 0.02) and, to a lesser extent, TNF-alpha (147 +/- 56% vs. 112 +/- 20%, NS) in 1 compared with 2 DR MM pairs.	Nitrogen	187-189	interleukin 10	Homo sapiens	12-17
16984173-1	2006	The observation of proton to nitrogen-15 heteronuclear Overhauser effects in the microcrystalline protein Crh is used to confirm that the principal mechanism of relaxation of amide nitrogens is due to the fluctuation of the N-H dipolar couplings caused by N-H bond dynamics.	Nitrogen	181-190	corticotropin releasing hormone	Homo sapiens	106-109
8639667-6	1996	It has been proposed that the extent of N-linked glycosylation at Asn-240 and Asn-269 in the third domain of ICAM-1 may regulate the binding avidity of ICAM-1 to Mac-1 [Diamond, M. S., Staunton, D. E., Marlin, S. D., &amp; Springer, T. A.	Nitrogen	40-41	intercellular adhesion molecule 1	Homo sapiens	109-115
16864577-7	2006	If Npr1 functions directly, then the ability of all good nitrogen sources to restrict Gln3 to the cytoplasm should be lost in an npr1Delta just as occurs when URE2 (encoding this well studied negative Gln3 regulator) is deleted.	Nitrogen	57-65	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	86-90
8639667-6	1996	It has been proposed that the extent of N-linked glycosylation at Asn-240 and Asn-269 in the third domain of ICAM-1 may regulate the binding avidity of ICAM-1 to Mac-1 [Diamond, M. S., Staunton, D. E., Marlin, S. D., &amp; Springer, T. A.	Nitrogen	40-41	intercellular adhesion molecule 1	Homo sapiens	152-158
8639667-6	1996	It has been proposed that the extent of N-linked glycosylation at Asn-240 and Asn-269 in the third domain of ICAM-1 may regulate the binding avidity of ICAM-1 to Mac-1 [Diamond, M. S., Staunton, D. E., Marlin, S. D., &amp; Springer, T. A.	Nitrogen	40-41	integrin subunit alpha M	Homo sapiens	162-167
11069924-9	2001	Therefore, the rate of protein translation can regulate the level of tyrosinase N-linked glycosylation, as well as other potential cotranslational maturation events.	Nitrogen	80-81	tyrosinase	Homo sapiens	69-79
16864577-8	2006	We show that nuclear localization of Gln3-Myc(13) in an npr1Delta occurred only with ammonia as the nitrogen source.	Nitrogen	100-108	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	37-41
16864577-9	2006	Other good nitrogen sources, e.g. glutamine, serine, or asparagine, restricted Gln3-Myc(13) to the cytoplasm of both wild type and npr1Delta cells.	Nitrogen	11-19	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	79-83
9172775-6	1996	Heterogeneity in the migration of purified GRP94 on native and denaturing PAGE was observed and demonstrated to reflect variability in the N-linked glycosylation state of the protein.	Nitrogen	139-140	heat shock protein 90 beta family member 1	Homo sapiens	43-48
16864577-11	2006	This suggests that the connection between Gln3 localization and Npr1 is indirect, arising from the influence of Npr1 on the ability of cells to utilize ammonia as a repressive nitrogen source.	Nitrogen	176-184	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
16967938-4	2006	This method allows for mild and efficient synthesis of diverse C-2 substituted N-containing heterocycles.	Nitrogen	79-80	complement C2	Homo sapiens	63-66
8866724-1	1996	Exposing 7-day-old rat pups to hypoxia, 8% oxygen/92% nitrogen, for 3 h alters glutamate (GLU), glutamine and glutamine synthetase (GS) activity in the striatum, frontal cortex and hippocampus.	Nitrogen	54-62	glutamate-ammonia ligase	Rattus norvegicus	110-130
11110783-0	2001	N-unsubstituted glucosamine in heparan sulfate of recycling glypican-1 from suramin-treated and nitrite-deprived endothelial cells.	Nitrogen	0-1	glypican 1	Homo sapiens	60-70
11110783-2	2001	We have analyzed the content of N-unsubstituted glucosamine in heparan sulfate from glypican-1 synthesized by endothelial cells during inhibition of (a) intracellular progression by brefeldin A, (b) heparan sulfate degradation by suramin, and/or (c) endogenous nitrite formation.	Nitrogen	32-33	glypican 1	Homo sapiens	84-94
16945841-6	2006	This new nitrogen input can balance the annual nitrogen biogeochemical budget in the Mediterranean Sea and should explain the high nitrate/phosphate ratio observed in deep waters.	Nitrogen	9-17	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	99-102
11036065-7	2001	Importantly, the mapping of N-linked glycosylation to the C-terminal domain of Nhx1 is indicative of an unexpected membrane topology, particularly with regard to the orientation of the tail region.	Nitrogen	28-29	bifunctional K:H/Na:H antiporter NHX1	Saccharomyces cerevisiae S288C	79-83
14533809-4	2001	Well-documented examples are: (i) blood group A antigen in primary lung carcinoma; (ii) bisecting beta1 --&gt; 4GlcNAc of N-linked structure in melanoma and other cancers; (iii) galactosylgloboside (GalGb4) in seminoma.	Nitrogen	115-116	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	98-103
11595423-1	2001	N alpha-methylhistamine (N alpha-MH) is one of an unusual metabolite of histamine that was found in Helicobacter pylori-infected stomachs and is believed to interact with specific histamine H(1), H(2) and H(3)-receptors to stimulate gastric acid secretion and gastrin release from isolated G-cells but the effects of N alpha-MH on gastric mucosal integrity have been little studied.	Nitrogen	0-1	gastrin	Rattus norvegicus	260-267
11595423-13	2001	We conclude that (1) N alpha-MH stimulates gastric acid secretion and exhibit gastroprotective activity against acid-independent noxious agents in the manner similar to that afforded by histamine; and (2) this protection involves an enhancement in the gastric microcirculation and release of gastrin acting via specific CCK-B/gastrin receptors but unexpectedly, appears to be unrelated to histamine H(2)-receptors.	Nitrogen	21-22	gastrin	Rattus norvegicus	292-299
11595423-13	2001	We conclude that (1) N alpha-MH stimulates gastric acid secretion and exhibit gastroprotective activity against acid-independent noxious agents in the manner similar to that afforded by histamine; and (2) this protection involves an enhancement in the gastric microcirculation and release of gastrin acting via specific CCK-B/gastrin receptors but unexpectedly, appears to be unrelated to histamine H(2)-receptors.	Nitrogen	21-22	gastrin	Rattus norvegicus	326-333
8561787-2	1996	In this work we demonstrate that glycosylasparaginase is also capable of catalyzing the synthesis of the N-glycosidic bond by N-beta-aspartylation of beta-glycosylamine using 1-amino-N-acetylglucosamine as the nucleophile and L-aspartic acid beta-methyl ester as the beta-aspartyl donor.	Nitrogen	105-106	aspartylglucosaminidase	Homo sapiens	33-53
8543840-10	1996	Thus, the naturally processed form of an env epitope containing an N-linked glycosylation site is derived from env protein that is not glycosylated at the relevant asparagine during biosynthesis.	Nitrogen	67-68	endogenous retrovirus group K member 20	Homo sapiens	41-44
8543840-10	1996	Thus, the naturally processed form of an env epitope containing an N-linked glycosylation site is derived from env protein that is not glycosylated at the relevant asparagine during biosynthesis.	Nitrogen	67-68	endogenous retrovirus group K member 20	Homo sapiens	111-114
8571387-3	1996	Measurements taken 72 h after drug treatment indicated that compared to animals receiving cisplatin only, ANP co-treated rats had lower post-treatment plasma creatinine concentrations (0.70 +/- 0.07 vs 1.3 +/- 0.17 mg/dl; P &lt; 0.05), blood urea nitrogen (BUN) concentrations (44.2 +/- 5.8 vs. 65.5 +/- 2.1 mg/dl; P &lt; 0.05) and higher post-treatment glomerular filtration rates (GFR) (0.71 +/- 0.18 vs. 0.14 +/- 0.03 ml/min; P &lt; 0.05).	Nitrogen	247-255	natriuretic peptide A	Rattus norvegicus	106-109
8615602-3	1996	MATERIALS AND METHODS: In this paper, investigation has been made of the correlation between cell surface glycosylation and anti-tumour activity of LAK cells by stimulating peripheral blood lymphocytes with interleukin-2, in the presence of inhibitors of N- and O-glycosylation.	Nitrogen	11-12	alpha kinase 1	Homo sapiens	148-151
8615602-4	1996	RESULTS: Inhibition of N- or O-glycosylation of proteins during IL-2 activation leads to a 70-80% decrease in the cytolytic activity of LAK cells against K562 and Daudi tumour cells, coinciding with drastic alterations in their cell surface carbohydrate profile.	Nitrogen	23-24	alpha kinase 1	Homo sapiens	136-139
11123894-4	2000	Human MMP-9 has three potential N-linked glycosylation sites and contains a Ser/Pro/Thr rich domain, known as the type V collagen-like domain, which is expected to be heavily O-glycosylated.	Nitrogen	32-33	matrix metallopeptidase 9	Homo sapiens	6-11
16945841-6	2006	This new nitrogen input can balance the annual nitrogen biogeochemical budget in the Mediterranean Sea and should explain the high nitrate/phosphate ratio observed in deep waters.	Nitrogen	47-55	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	99-102
11119727-1	2000	The human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively.	Nitrogen	107-108	adrenomedullin	Homo sapiens	245-259
16912292-3	2006	When HIV-1-infected CEM cell cultures were exposed to CV-N in a dose-escalating manner, a total of eight different amino acid mutations exclusively located at N-glycosylation sites in the envelope surface gp120 were observed.	Nitrogen	57-58	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	205-210
11119727-1	2000	The human calcitonin (CT) receptor-like receptor (hCRLR) of the B family of G protein-coupled receptors is N-glycosylated and associates with receptor-activity-modifying proteins for functional interaction with CT gene-related peptide (CGRP) or adrenomedullin (ADM), respectively.	Nitrogen	107-108	adrenomedullin	Homo sapiens	261-264
11428337-2	2000	Immune factors such as interferon-gamma, tumour necrosis factor and reactive nitrogen intermediates derived from nitric oxide are known to be important inducers of HSP70 production and are also known to be produced during the immune response to acute T. gondii infection.	Nitrogen	77-85	heat shock protein family A (Hsp70) member 4	Homo sapiens	164-169
8924590-4	1996	The cis adducts as well as the (+)-syn-BPDEt-N2-dG adduct are chemically stable for several weeks when stored at &lt; or = 4 degrees C in darkness.	Nitrogen	45-47	synemin	Homo sapiens	35-38
16946276-9	2006	Copper-deprived S. cerevisiae cells expressing spao1(+) required a functional atx1(+) gene for growth on minimal medium containing ethylamine as the sole nitrogen source.	Nitrogen	154-162	copper metallochaperone ATX1	Saccharomyces cerevisiae S288C	78-82
8750891-9	1995	The 5-HT2C receptor cell line (3T3/2C) was grown in the presence of tunicamycin to metabolically inhibit N-linked glycosylation.	Nitrogen	105-106	5-hydroxytryptamine receptor 2C	Rattus norvegicus	4-10
11180637-0	2000	Identification of the nitrogen-based blister agents bis(2-chloroethyl)methylamine (HN-2) and tris(2-chloroethyl)amine (HN-3) and their hydrolysis products on soil using ion trap secondary ion mass spectrometry.	Nitrogen	22-30	MT-RNR2 like 3 (pseudogene)	Homo sapiens	119-123
11076970-1	2000	Target of rapamycin signaling links nitrogen quality to the activity of the Rtg1 and Rtg3 transcription factors.	Nitrogen	36-44	Rtg1p	Saccharomyces cerevisiae S288C	76-80
16906340-0	2006	HB-1, an acute myeloid leukemic cell line with the capability of infiltrating into the brain in CBA/N mice.	Nitrogen	100-101	paternally expressed 10	Mus musculus	0-4
11095006-2	2000	Total measured N losses (TNm) were 5.56+/-2.26 g/day (69.9+/-11.1% in dialysate, 16.3+/-10.6% in urine, and 13.6+/-4.6% in feces).	Nitrogen	15-16	teneurin transmembrane protein 1	Homo sapiens	25-28
8575790-3	1995	Characterization of these monoclonal antibodies by immunoblot analysis revealed that they all reacted with recombinant, N-glycosylated ST2 protein that was secreted from COS7 cells transiently transfected with a mammalian expression vector carrying ST2 cDNA.	Nitrogen	120-121	ST2	Homo sapiens	135-138
8575790-3	1995	Characterization of these monoclonal antibodies by immunoblot analysis revealed that they all reacted with recombinant, N-glycosylated ST2 protein that was secreted from COS7 cells transiently transfected with a mammalian expression vector carrying ST2 cDNA.	Nitrogen	120-121	ST2	Homo sapiens	249-252
8575790-4	1995	The recombinant N-glycosylated ST2 protein could be immunoprecipitated by 5 out of 6 species of the IgG class monoclonal antibodies.	Nitrogen	16-17	ST2	Homo sapiens	31-34
7616236-1	1995	The rat 5-hydroxytryptamine2C (5-HT2C) receptor was identified as N-glycosylated polypeptide of 60-kDa apparent molecular mass using antibodies against its putative third and fourth (C-terminal) cytoplasmic domain.	Nitrogen	66-67	5-hydroxytryptamine receptor 2C	Rattus norvegicus	31-37
8572298-6	1995	We have shown that recombinant human lysosomal hydrolase alpha-galactosidase A is N-glycosylated with both sialylated and phosphorylated oligosaccharides.	Nitrogen	82-83	galactosidase alpha	Homo sapiens	57-78
11052678-3	2000	The library was screened against the biotinylated N- and C-terminal SH2 domains of protein tyrosine phosphatase SHP-1, and the beads that carry high-affinity ligands of the SH2 domains were identified using an enzyme-linked assay involving a streptavidin-alkaline phosphatase conjugate.	Nitrogen	50-51	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	112-117
10903319-1	2000	A new beta1,4-N-acetylglucosaminyltransferase (GnT) responsible for the formation of branched N-linked complex-type sugar chains has been purified 64,000-fold in 16% yield from a homogenate of hen oviduct by column chromatography procedures using Q-Sepharose FF, Ni(2+)-chelating Sepharose FF, and UDP-hexanolamine-agarose.	Nitrogen	14-15	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	6-11
11011100-5	2000	Measurements of nitrogen-assimilating enzyme activities of these fruits showed a decrease in glutamine synthetase (GS, EC 6.3.1.2) during fruit ripening and a concomitant increase in NADH-glutamate dehydrogenase (GDH, EC 1.4.1.3) and aspartate aminotransferase (EC 2.6.1.1) activities.	Nitrogen	16-24	glutamine synthetase	Solanum lycopersicum	93-113
16906340-1	2006	An acute myeloid leukemic HB-1 cell line was cloned and established from the spleen cells of irradiated CBA/N mice.	Nitrogen	108-109	paternally expressed 10	Mus musculus	26-30
16714110-1	2006	The purpose of the present study was the synthesis and the biological screening of new analogues of N/OFQ(1-13)NH2, the minimal sequence maintaining the same activity as the natural peptide nociceptin.	Nitrogen	100-101	prepronociceptin	Rattus norvegicus	190-200
11027576-2	2000	It has a mutation in the DAD1 gene and enters apoptosis at the restrictive temperature of 39 degrees C. The defect of Dad1p causes a loss of N-linked glycosylation; therefore, it was thought that an inhibition of N-linked glycosylation induced apoptosis.However, tunicamycin, a potent inhibitor of N-linked glycosylation, had not caused apoptosis in wild-type BHK21 cells.	Nitrogen	141-142	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	Mesocricetus auratus	25-29
11027576-2	2000	It has a mutation in the DAD1 gene and enters apoptosis at the restrictive temperature of 39 degrees C. The defect of Dad1p causes a loss of N-linked glycosylation; therefore, it was thought that an inhibition of N-linked glycosylation induced apoptosis.However, tunicamycin, a potent inhibitor of N-linked glycosylation, had not caused apoptosis in wild-type BHK21 cells.	Nitrogen	141-142	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	Mesocricetus auratus	118-123
11027576-2	2000	It has a mutation in the DAD1 gene and enters apoptosis at the restrictive temperature of 39 degrees C. The defect of Dad1p causes a loss of N-linked glycosylation; therefore, it was thought that an inhibition of N-linked glycosylation induced apoptosis.However, tunicamycin, a potent inhibitor of N-linked glycosylation, had not caused apoptosis in wild-type BHK21 cells.	Nitrogen	213-214	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	Mesocricetus auratus	25-29
11027576-2	2000	It has a mutation in the DAD1 gene and enters apoptosis at the restrictive temperature of 39 degrees C. The defect of Dad1p causes a loss of N-linked glycosylation; therefore, it was thought that an inhibition of N-linked glycosylation induced apoptosis.However, tunicamycin, a potent inhibitor of N-linked glycosylation, had not caused apoptosis in wild-type BHK21 cells.	Nitrogen	213-214	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1	Mesocricetus auratus	118-123
11010866-9	2000	AtzA catalyzed hydrolytic dechlorination when one nitrogen substituent was alkylated and the other was a free amino group.	Nitrogen	50-58	atzA	Pseudomonas sp. ADP	0-4
11465082-5	2000	Human FMO3 is sensitive to steric features of the substrate and aliphatic amines with linkages between the nitrogen atom and a large aromatic group such as a phenothiazine of at least five carbons are N-oxygenated significantly more efficiently than those substrates with two or three carbons.	Nitrogen	107-115	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	6-10
20575852-9	2000	We present evidence that the widespread assumption that dopamine transporter blockers require an amine nitrogen in their structure is incorrect as non-amines are effective blockers of transporters.	Nitrogen	103-111	solute carrier family 6 member 3	Homo sapiens	56-76
10888671-0	2000	Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages.	Nitrogen	34-35	vesicle associated membrane protein 7	Homo sapiens	15-21
10773339-0	2000	Distribution of the Mo-enzymes aldehyde oxidase, xanthine dehydrogenase and nitrate reductase in maize (Zea mays L.) nodal roots as affected by nitrogen and salinity.	Nitrogen	144-152	indole-3-acetaldehyde oxidase	Zea mays	31-47
10857618-3	2000	The preference for Hg2+ stems from the favorable positioning of the nitrogen or sulfur atoms for linear coordination of Hg2+, whereas the cryptand derivative favors Pb2+ because of its larger cavity size.	Nitrogen	68-76	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	19-22
10857618-3	2000	The preference for Hg2+ stems from the favorable positioning of the nitrogen or sulfur atoms for linear coordination of Hg2+, whereas the cryptand derivative favors Pb2+ because of its larger cavity size.	Nitrogen	68-76	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	120-123
10799523-0	2000	Nitrogen catabolite repression of DAL80 expression depends on the relative levels of Gat1p and Ure2p production in Saccharomyces cerevisiae.	Nitrogen	0-8	Dal80p	Saccharomyces cerevisiae S288C	34-39
10799523-1	2000	GATA family activators (Gln3p and Gat1p) and repressors (Dal80p and Deh1p) regulate nitrogen catabolite repression (NCR)-sensitive transcription in Saccharomyces cerevisiae presumably via their competitive binding to the GATA sequences upstream of NCR-sensitive genes.	Nitrogen	84-92	Dal80p	Saccharomyces cerevisiae S288C	57-63
10779691-3	2000	On pulse irradiation of nitrogen-saturated dAMP aqueous solution containing 0.2 M t-BuOH and one of PPGs or their analogs, the transient absorption spectrum of the radical anion of dAMP decayed with the formation of that of the radical anion of PPGs or their analogs within several decades of microseconds after electron pulse irradiation.	Nitrogen	24-32	Amphiphysin	Drosophila melanogaster	43-47
10779691-3	2000	On pulse irradiation of nitrogen-saturated dAMP aqueous solution containing 0.2 M t-BuOH and one of PPGs or their analogs, the transient absorption spectrum of the radical anion of dAMP decayed with the formation of that of the radical anion of PPGs or their analogs within several decades of microseconds after electron pulse irradiation.	Nitrogen	24-32	Amphiphysin	Drosophila melanogaster	181-185
10983282-4	2000	Among the compounds synthesized, the N-1H-indol-3-propionyl derivative exhibited an improved, at the micromolar range, affinity for the CCK-A receptor in comparison to that of either, the N-unsubstituted derivative and asperlicin.	Nitrogen	37-38	cholecystokinin A receptor	Homo sapiens	136-150
10764842-1	2000	The influence of N-linked glycosylation on the activity and trafficking of membrane associated and soluble forms of the STtyr isoform of the ST6Gal I has been evaluated.	Nitrogen	17-18	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	141-149
10758005-5	2000	The level of N-sulfation increased from 40% in control cells to 60% and 80%, respectively, in NDST-1 and NDST-2 transfected cells.	Nitrogen	13-14	N-deacetylase and N-sulfotransferase 2	Homo sapiens	105-111
10744717-5	2000	By introducing a basic nitrogen in the core structure of the inhibitor, a salt bridge was formed to Asp-48 in PTP1B.	Nitrogen	23-31	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	110-115
10744717-6	2000	In contrast, the basic nitrogen causes repulsion in other PTPs containing an asparagine in the equivalent position resulting in a remarkable selectivity for PTP1B.	Nitrogen	23-31	protein tyrosine phosphatase, non-receptor type 1	Mus musculus	157-162
10720432-1	2000	Dad1 has been shown to play a role in preventing apoptotic cell death and in regulating levels of N-linked glycosylation in Saccharomyces cerevisiae and the BHK hamster cell line.	Nitrogen	98-99	Dad1p	Saccharomyces cerevisiae S288C	0-4
10778863-6	2000	The decreased concentration of Mn-SOD in the liver, kidney, and cardiac muscle from DM rats was also reversed by N treatment.	Nitrogen	113-114	superoxide dismutase 2	Rattus norvegicus	31-37
10713140-0	2000	Mutations at critical N-glycosylation sites reduce tyrosinase activity by altering folding and quality control.	Nitrogen	22-23	tyrosinase	Homo sapiens	51-61
10713140-2	2000	Mutations at a single N-glycosylation sequon of tyrosinase have been reported to be responsible for oculocutaneous albinism type IA in humans, characterized by inactive tyrosinase and the total absence of pigmentation.	Nitrogen	22-23	tyrosinase	Homo sapiens	48-58
10713140-2	2000	Mutations at a single N-glycosylation sequon of tyrosinase have been reported to be responsible for oculocutaneous albinism type IA in humans, characterized by inactive tyrosinase and the total absence of pigmentation.	Nitrogen	22-23	tyrosinase	Homo sapiens	169-179
10713140-5	2000	Analysis of the folding pathway and activity of 15 tyrosinase mutants lacking one or more of the occupied N-glycosylation sites shows that glycans at any two N-glycosylation sites are sufficient to interact with calnexin and give partial activity, but a specific pair of sites (Asn(86) and Asn(371)) is required for full activity.	Nitrogen	106-107	tyrosinase	Homo sapiens	51-61
10713140-5	2000	Analysis of the folding pathway and activity of 15 tyrosinase mutants lacking one or more of the occupied N-glycosylation sites shows that glycans at any two N-glycosylation sites are sufficient to interact with calnexin and give partial activity, but a specific pair of sites (Asn(86) and Asn(371)) is required for full activity.	Nitrogen	158-159	tyrosinase	Homo sapiens	51-61
10713140-8	2000	By correlating the degree of folding with the activity of tyrosinase, we propose a local folding mechanism for tyrosinase that can explain the mechanism of inactivation of tyrosinase N-glycosylation mutants found in certain pigmentation disorders.	Nitrogen	183-184	tyrosinase	Homo sapiens	58-68
10713140-8	2000	By correlating the degree of folding with the activity of tyrosinase, we propose a local folding mechanism for tyrosinase that can explain the mechanism of inactivation of tyrosinase N-glycosylation mutants found in certain pigmentation disorders.	Nitrogen	183-184	tyrosinase	Homo sapiens	111-121
10713140-8	2000	By correlating the degree of folding with the activity of tyrosinase, we propose a local folding mechanism for tyrosinase that can explain the mechanism of inactivation of tyrosinase N-glycosylation mutants found in certain pigmentation disorders.	Nitrogen	183-184	tyrosinase	Homo sapiens	111-121
10719002-0	2000	Relationship between leaf nitrogen and photosynthetic rate for three NAD-ME and three NADP-ME C4 grasses.	Nitrogen	26-34	malic enzyme 1	Homo sapiens	86-93
10710502-7	2000	ST treatment also increased plasma insulin-like growth factor I (+100%) and insulin (+125%) concentrations and decreased plasma urea nitrogen concentrations (-53%).	Nitrogen	133-141	somatotropin	Sus scrofa	0-2
10698460-2	2000	The comparisons of the in vitro antitumor activities of the 2-substituted analogues with the benzothiopyranoindazole chemotypes indicate that the positioning of the nitrogen atom at C-9 (9-aza analogue 4d) leads to a substrate with potent antitumor activity.	Nitrogen	165-173	complement C9	Homo sapiens	182-185
10629046-1	2000	The proline utilization pathway in Saccharomyces cerevisiae is regulated by the Put3p transcriptional activator in response to the presence of the inducer proline and the quality of the nitrogen source in the growth medium.	Nitrogen	186-194	Put3p	Saccharomyces cerevisiae S288C	80-85
10629046-2	2000	Put3p is constitutively bound to the promoters of its target genes, PUT1 and PUT2, under all conditions studied but activates transcription to the maximum extent only in the absence of rich nitrogen sources and in the presence of proline (i.e., when proline serves as the sole source of nitrogen).	Nitrogen	190-198	Put3p	Saccharomyces cerevisiae S288C	0-5
10629046-2	2000	Put3p is constitutively bound to the promoters of its target genes, PUT1 and PUT2, under all conditions studied but activates transcription to the maximum extent only in the absence of rich nitrogen sources and in the presence of proline (i.e., when proline serves as the sole source of nitrogen).	Nitrogen	287-295	Put3p	Saccharomyces cerevisiae S288C	0-5
10629046-5	2000	Examination of Put3p isolated from cells grown on a variety of nitrogen sources showed that it was differentially phosphorylated as a function of the quality of the nitrogen source: the poorer the nitrogen source, the slower the gel migration of the phosphoforms.	Nitrogen	63-71	Put3p	Saccharomyces cerevisiae S288C	15-20
10629046-5	2000	Examination of Put3p isolated from cells grown on a variety of nitrogen sources showed that it was differentially phosphorylated as a function of the quality of the nitrogen source: the poorer the nitrogen source, the slower the gel migration of the phosphoforms.	Nitrogen	165-173	Put3p	Saccharomyces cerevisiae S288C	15-20
10629046-5	2000	Examination of Put3p isolated from cells grown on a variety of nitrogen sources showed that it was differentially phosphorylated as a function of the quality of the nitrogen source: the poorer the nitrogen source, the slower the gel migration of the phosphoforms.	Nitrogen	165-173	Put3p	Saccharomyces cerevisiae S288C	15-20
10629046-10	2000	These results demonstrate a correlation between the phosphorylation status of Put3p and its ability to activate its target genes and suggest that there are two signals, proline induction and quality of nitrogen source, impinging on Put3p that act synergistically for maximum expression of the proline utilization pathway.	Nitrogen	202-210	Put3p	Saccharomyces cerevisiae S288C	78-83
10629046-10	2000	These results demonstrate a correlation between the phosphorylation status of Put3p and its ability to activate its target genes and suggest that there are two signals, proline induction and quality of nitrogen source, impinging on Put3p that act synergistically for maximum expression of the proline utilization pathway.	Nitrogen	202-210	Put3p	Saccharomyces cerevisiae S288C	232-237
10612663-3	2000	Our present results further indicate that these phenotypic differences represent linked properties that correlate with the number of N-glycosylation sites associated with the single neutralization epitope on the short ectodomain of the primary envelope glycoprotein, VP-3P.	Nitrogen	133-134	endogenous retrovirus group K member 20	Homo sapiens	244-265
11013410-1	2000	The major pathway of bioactivation of procarcinogenic heterocyclic aromatic amines (HCAs) is cytochrome P450 1A2 (CYP1A2)-catalyzed N-hydroxylation and subsequent esterification by O-acetyltransferase (O-AT).	Nitrogen	132-133	CAS1 domain containing 1	Homo sapiens	181-200
11013410-1	2000	The major pathway of bioactivation of procarcinogenic heterocyclic aromatic amines (HCAs) is cytochrome P450 1A2 (CYP1A2)-catalyzed N-hydroxylation and subsequent esterification by O-acetyltransferase (O-AT).	Nitrogen	132-133	CAS1 domain containing 1	Homo sapiens	202-206
10617131-5	2000	Peptide: N-glycosidase F and endoglycosidase H treatment of the CLN2p reduced its molecular mass to 39.5 and 40.5 kDa, respectively, suggesting the presence of as many as five N-glycosylated residues.	Nitrogen	9-10	tripeptidyl peptidase 1	Homo sapiens	64-69
10570024-2	1999	Among the 10 cDNA-expressed CYPs studied (CYP1A1, CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4), only CYP2B6 could catalyze S-mephobarbital N-demethylation.	Nitrogen	15-16	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	90-97
10641793-5	1999	i.e. by attaching either an extra propargyl or a methyl group to the nitrogen atom, the potency of inhibition of MAO-B activity was drastically reduced and inhibition of MAO-A activity substantially increased.	Nitrogen	69-77	monoamine oxidase B	Homo sapiens	113-118
10644005-6	1999	The incorporation of 3H-glucosamine, as a marker of N-glycosylation, into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	52-53	lysosomal-associated membrane protein 1	Mus musculus	89-95
10644005-6	1999	The incorporation of 3H-glucosamine, as a marker of N-glycosylation, into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	147-148	lysosomal-associated membrane protein 1	Mus musculus	89-95
10644005-7	1999	These results indicate N-glycosylation as an important regulatory pathway for MSH-induced melanogenesis, and further suggest that altered N-linked glycosylation may be an underlying mechanism for regulation of both melanogenesis and metastasis in macrophage x melanoma hybrids.	Nitrogen	23-24	msh homeobox 1	Mus musculus	78-81
10644005-7	1999	These results indicate N-glycosylation as an important regulatory pathway for MSH-induced melanogenesis, and further suggest that altered N-linked glycosylation may be an underlying mechanism for regulation of both melanogenesis and metastasis in macrophage x melanoma hybrids.	Nitrogen	138-139	msh homeobox 1	Mus musculus	78-81
7774058-0	1995	Galactosylation of N- and O-linked carbohydrate moieties of IgA1 and IgG in IgA nephropathy.	Nitrogen	19-20	immunoglobulin heavy constant alpha 1	Homo sapiens	60-64
7774058-3	1995	IgA1 is rich in carbohydrate, carrying N-linked moieties in common with IgG, but also O-linked sugars, which are rare in serum proteins, and not expressed by IgG or IgA2.	Nitrogen	39-40	immunoglobulin heavy constant alpha 1	Homo sapiens	0-4
7782767-1	1995	The Epstein-Barr virus (EBV) open reading frame BDLF3 is predicted to code for a glycoprotein on the basis that it contains sequences with signal peptide and transdomain characteristics and nine potential N-linked glycosylation sites.	Nitrogen	205-206	envelope glycoprotein 150	Human gammaherpesvirus 4	48-53
7754374-3	1995	KAI1 specifies a protein of 267 amino acids, with four hydrophobic and presumably transmembrane domains and one large extracellular hydrophilic domain with three potential N-glycosylation sites.	Nitrogen	172-173	CD82 molecule	Homo sapiens	0-4
7588578-1	1995	Based on computer calculations one N-glycosylation site was deduced from the cDNA data of Phl p I.	Nitrogen	35-36	BCR activator of RhoGEF and GTPase	Homo sapiens	90-93
7797129-6	1995	Infusion of somatostatin prevented increase of glucagon for 24 hours after surgery, and prevented the negative changes in postoperative nitrogen homeostasis resulting from the postoperative changes in hepatic nitrogen conversion, suggesting glucagon as mediator.	Nitrogen	136-144	somatostatin	Homo sapiens	12-24
7797129-6	1995	Infusion of somatostatin prevented increase of glucagon for 24 hours after surgery, and prevented the negative changes in postoperative nitrogen homeostasis resulting from the postoperative changes in hepatic nitrogen conversion, suggesting glucagon as mediator.	Nitrogen	209-217	somatostatin	Homo sapiens	12-24
7758971-4	1995	Cys residues critical to the immunoglobulin (Ig) fold structure and four sites of N-linked glycosylation are absolutely conserved in ICAM-1 from all species.	Nitrogen	82-83	intercellular adhesion molecule 1	Canis lupus familiaris	133-139
7613477-3	1995	In addition to the four expected N-linked glycopeptides of LCAT, a di-O-linked glycopeptide was detected, as well as three additional glycopeptides.	Nitrogen	33-34	lecithin-cholesterol acyltransferase	Homo sapiens	59-63
7613477-5	1995	All four potential N-linked glycosylation sites (Asn20, Asn84, Asn272, and Asn384) of LCAT were determined to contain sialylated triantennary and/or biantennary complex structures.	Nitrogen	19-20	lecithin-cholesterol acyltransferase	Homo sapiens	86-90
7768225-6	1995	Comparisons of blood urea nitrogen (BUN) and uric acid by genotype indicated elevated levels among ALAD-2 individuals (p = 0.03 and 0.07, respectively).	Nitrogen	26-34	aminolevulinate dehydratase	Homo sapiens	99-103
7776822-1	1995	To study the N-linked glycosylation properties of the CB1 receptor, rat brain membranes were treated with exo- and endoglycosidases.	Nitrogen	13-14	cannabinoid receptor 1	Rattus norvegicus	54-57
7776822-8	1995	Among three potential N-linked glycosylation sites on the N-terminus of the CB1 receptor, only two sites are actually glycosylated.	Nitrogen	22-23	cannabinoid receptor 1	Rattus norvegicus	76-79
7539640-2	1995	The expression of GmN56 was induced almost concomitantly with the onset of nitrogen fixation, together with leghemoglobin and other late nodulin genes.	Nitrogen	75-83	probable 2-isopropylmalate synthase	Glycine max	18-23
7539640-4	1995	The predicted amino acid sequence of the GmN56 protein exhibits significant homology to those of LeuA (isopropylmalate synthase) of several microorganisms and NifV (putative homocitrate synthase) of nitrogen-fixing bacteria, suggesting that GmN56 encodes an enzyme catalyzing a reaction involving acetyl-CoA and alpha-keto acid as substrates.	Nitrogen	199-207	probable 2-isopropylmalate synthase	Glycine max	41-46
7799961-0	1995	The Saccharomyces cerevisiae Leu3 protein activates expression of GDH1, a key gene in nitrogen assimilation.	Nitrogen	86-94	leucine-responsive transcriptional regulator LEU3	Saccharomyces cerevisiae S288C	29-33
8584670-2	1995	Structural requirements of a substrate for PAO are two positively charged amino groups, separated by a short carbon chain and an alkyl substituent on one or both nitrogen atoms.	Nitrogen	162-170	polyamine oxidase	Homo sapiens	43-46
8844797-4	1995	Urinary metabolites of IQ arise from a combination of cytochrome P-450 mediated N-demethylation, N-hydroxylation, or ring oxidation at the C-5 position and conjugation with sulfate or glucuronide.	Nitrogen	80-81	cytochrome P450 family 1 subfamily A member 1	Macaca fascicularis	54-70
8844797-7	1995	N-Hydroxy-IQ-N-glucuronide was found in urine of monkeys indicating that metabolic activation via cytochrome P-450-mediated N-hydroxylation occurs in vivo and supporting the theory N-hydroxy-IQ plays a role in the initiation of IQ-induced hepatocarcinogenesis.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 1	Macaca fascicularis	98-114
8844812-4	1995	Using metabolic inhibitors, bile duct ligation, and intravenous dosing studies, a new hypothesis for colorectal carcinogenesis is proposed involving N-oxidation of PhIP by hepatic cytochrome P-4501A2 (CYP1A2) and O-acetylation by the polymorphic acetyltransferase (NAT2).	Nitrogen	149-150	N-acetyltransferase 2	Homo sapiens	265-269
7998989-7	1994	CD47 has six potential N-glycosylation sites, five of which are in an Ig superfamily domain.	Nitrogen	23-24	CD47 molecule	Homo sapiens	0-4
7534460-10	1994	This putative hGal receptor is glycosylated since its molecular size was reduced after treatment with endoglycosidase F. Receptors bound to 125I-labelled hGal could be specifically adsorbed to wheat germ agglutinin and ricinus communis agglutinin, suggesting that receptor glycosylation involves N-acetyl glucosamine and galactose respectively.	Nitrogen	296-297	galanin and GMAP prepropeptide	Homo sapiens	14-18
7534460-10	1994	This putative hGal receptor is glycosylated since its molecular size was reduced after treatment with endoglycosidase F. Receptors bound to 125I-labelled hGal could be specifically adsorbed to wheat germ agglutinin and ricinus communis agglutinin, suggesting that receptor glycosylation involves N-acetyl glucosamine and galactose respectively.	Nitrogen	296-297	galanin and GMAP prepropeptide	Homo sapiens	154-158
7858228-8	1994	The GS1-4 gene transcript level remained constant in shoots of treated seedlings, whereas in roots, it exhibited relatively minor, but complex responses to these two nitrogen sources.	Nitrogen	166-174	glutamine synthetase root isozyme 4	Zea mays	4-9
7919388-4	1994	We report the presence of a 65-kD precursor of gp91-phox in the membrane fraction of both p22-phox-deficient cell lines, corresponding to the core protein with N-linked carbohydrate side chains in the high mannose form.	Nitrogen	160-161	cytochrome b-245 beta chain	Homo sapiens	47-56
7945410-9	1994	Asparagine-linked complex chain N-glycosylation of the purified MCR was also observed.	Nitrogen	32-33	nuclear receptor subfamily 3 group C member 2	Bos taurus	64-67
15299369-7	1994	The N atom of Au(CN)(2)(-) is within hydrogen-bonding distance of the zinc-bound H(2)O/OH(-) group which shifts by about 0.4 A away from the zinc ion in relation to its position in the native HCAI.	Nitrogen	4-5	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	192-196
8062822-1	1994	In Saccharomyces cerevisiae, the transport of ammonium across the plasma membrane for use as a nitrogen source is mediated by at least two functionally distinct transport systems whose respective encoding genes are called MEP1 and MEP2.	Nitrogen	95-103	ammonium permease MEP2	Saccharomyces cerevisiae S288C	231-235
8050502-0	1994	N-glycosylation of erythropoietin is critical for apical secretion by Madin-Darby canine kidney cells.	Nitrogen	0-1	erythropoietin	Canis lupus familiaris	19-33
8050502-4	1994	Replacement of asparagine residues at all N-glycosylation sites of Epo with glutamine by site-directed mutagenesis resulted in roughly equal secretion from apical and basolateral domains.	Nitrogen	42-43	erythropoietin	Canis lupus familiaris	67-70
8045902-1	1994	Expression of the nitrogen catabolic genes in Saccharomyces cerevisiae, including those of the gamma-aminobutyric acid (UGA) and allantoin (DAL) pathways, is regulated positively by the GLN3 protein and negatively by the DAL80 protein.	Nitrogen	18-26	Dal80p	Saccharomyces cerevisiae S288C	221-226
8034633-6	1994	Consistent with their mechanisms of action on previously described substrates, endonuclease III removes 5-OHdC and 5-OHdU via a N-glycosylase/beta-elimination reaction, FPG follows a N-glycosylase/beta,delta-elimination reaction, and uracil N-glycosylase removes 5-OHdU by N-glycosylase action leaving behind an abasic site.	Nitrogen	128-129	endonuclease III	Escherichia coli	79-95
8027080-13	1994	Strains lacking a functional CKB2 gene appear to grow normally on both fermentable and non-fermentable carbon sources, mate and sporulate normally, and display normal resistance to nitrogen starvation and heat shock.	Nitrogen	181-189	casein kinase 2 regulatory subunit CKB2	Saccharomyces cerevisiae S288C	29-33
8201591-0	1994	CCK-A-selective tetrapeptides containing lys(N epsilon)-amide residues: favorable in vivo and in vitro effects of N-methylation at the aspartyl residue.	Nitrogen	45-46	cholecystokinin	Rattus norvegicus	0-3
8043630-4	1994	The analysis of the absorption band shifts of Raman spectra evidences the changes in the base torsion angle around the glycoside bond to the values characteristic of the syn-conformation and the interaction both with phosphates and nitrogen bases.	Nitrogen	232-240	synemin	Homo sapiens	170-173
8125748-8	1994	This recovery of pHi was not observed during anoxia, whether induced by PMMA lens wear or exposure to 100% N2.	Nitrogen	107-109	glucose-6-phosphate isomerase	Oryctolagus cuniculus	17-20
8114741-12	1994	In addition, wild-type diploid strains lacking PHD1 undergo pseudohyphal growth when starved for nitrogen.	Nitrogen	97-105	Phd1p	Saccharomyces cerevisiae S288C	47-51
8122360-5	1994	In particular, CD45, one of the major T cell glycoproteins, appeared to be partially sialylated on N- and O-linked carbohydrate moieties.	Nitrogen	99-100	protein tyrosine phosphatase receptor type C	Homo sapiens	15-19
8307000-0	1994	Glycosylation of two recombinant human uterine tissue plasminogen activator variants carrying an additional N-glycosylation site in the epidermal-growth-factor-like domain.	Nitrogen	108-109	chromosome 20 open reading frame 181	Homo sapiens	47-75
8253794-1	1993	The cartilage matrix glycoprotein fibromodulin contains four N-linked glycosylation sites which act as acceptors for the addition of sulfated polylactosamine (keratan sulfate).	Nitrogen	61-62	fibromodulin	Homo sapiens	34-46
7504463-2	1993	Along with the structural motifs of a G-protein coupled receptor, sequence analysis reveals that the monkey FSHR is highly homologous to the human FSHR and has specific features such as N-linked glycosylation sites which are identical to the human FSHR but not present in the rat or ovine FSHR.	Nitrogen	186-187	follicle stimulating hormone receptor	Homo sapiens	108-112
7504463-2	1993	Along with the structural motifs of a G-protein coupled receptor, sequence analysis reveals that the monkey FSHR is highly homologous to the human FSHR and has specific features such as N-linked glycosylation sites which are identical to the human FSHR but not present in the rat or ovine FSHR.	Nitrogen	186-187	follicle stimulating hormone receptor	Homo sapiens	147-151
7504463-2	1993	Along with the structural motifs of a G-protein coupled receptor, sequence analysis reveals that the monkey FSHR is highly homologous to the human FSHR and has specific features such as N-linked glycosylation sites which are identical to the human FSHR but not present in the rat or ovine FSHR.	Nitrogen	186-187	follicle stimulating hormone receptor	Homo sapiens	147-151
8246228-0	1993	Transformation of heterocyclic reversible monoamine oxidase-B inactivators into irreversible inactivators by N-methylation.	Nitrogen	109-110	monoamine oxidase B	Homo sapiens	42-61
8240300-0	1993	Site-directed removal of N-glycosylation sites in the bovine cation-dependent mannose 6-phosphate receptor: effects on ligand binding, intracellular targetting and association with binding immunoglobulin protein.	Nitrogen	25-26	mannose-6-phosphate receptor, cation dependent	Bos taurus	61-106
8240300-1	1993	The bovine cation-dependent mannose 6-phosphate receptor (CD-MPR) contains five potential N-linked glycosylation sites, four of which are utilized.	Nitrogen	90-91	mannose-6-phosphate receptor, cation dependent	Bos taurus	11-56
8240300-1	1993	The bovine cation-dependent mannose 6-phosphate receptor (CD-MPR) contains five potential N-linked glycosylation sites, four of which are utilized.	Nitrogen	90-91	mannose-6-phosphate receptor, cation dependent	Bos taurus	58-64
8240300-7	1993	Furthermore, the association of the various glycosylation-deficient forms of the CD-MPR with BiP correlated inversely with their ability to bind Man-6-P. From these results we conclude that N-glycosylation of the bovine CD-MPR facilities the folding of the nascent polypeptide chain into a conformation that is conductive for intracellular transport and ligand binding.	Nitrogen	190-191	mannose-6-phosphate receptor, cation dependent	Bos taurus	220-226
8230112-4	1993	Specifically, the effect of modification of the side chain attached to the nitrogen at C-7 was explored in an attempt to improve the potency and spectrum of activity.	Nitrogen	75-83	complement C7	Homo sapiens	87-90
10537138-2	1999	The human secretin receptor (hSR) is a glycoprotein consisting of 440 amino acids, of which there are 5 putative N-linked glycosylation sites at positions Asn72, Asn100, Asn106, Asn128 (N-terminal ectodomain), and Asn291 (second exoloop).	Nitrogen	113-114	HSR	Homo sapiens	29-32
10510387-5	1999	Examination of accessory cell functions associated with resistance to T. gondii revealed that RelB-/- macrophages stimulated with IFN-gamma plus LPS or TNF-alpha produced IL-12 as well as reactive nitrogen intermediates and inhibited parasite replication similar to WT macrophages.	Nitrogen	197-205	avian reticuloendotheliosis viral (v-rel) oncogene related B	Mus musculus	94-98
10479296-5	1999	Congeners in which the amide nitrogen atom was attached to the aralkyl moiety of the GBR molecule showed moderate affinity (K(i) = 51-61 nM) and selectivity for the dopamine transporter (DAT) site.	Nitrogen	29-37	solute carrier family 6 member 3	Homo sapiens	165-185
10479296-5	1999	Congeners in which the amide nitrogen atom was attached to the aralkyl moiety of the GBR molecule showed moderate affinity (K(i) = 51-61 nM) and selectivity for the dopamine transporter (DAT) site.	Nitrogen	29-37	solute carrier family 6 member 3	Homo sapiens	187-190
10510155-0	1999	Evidence for involvement of polymorphic CYP2C19 and 2C9 in the N-demethylation of sertraline in human liver microsomes.	Nitrogen	63-64	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	40-47
10530928-9	1999	Thus, both enantiomers of 1 bound to the dopamine D2 receptor model in a similar fashion: a reinforced electrostatic interaction was present between the protonated nitrogen atoms and Asp114 in TM3; their carbonyl groups accepted a H-bond from Ser121 in TM3; their amide NH groups acted as H-bond donor to Tyr416 in TM7; and their benzamide phenyl rings were involved in a hydrophobic edge-to-face interaction with Trp386 in TM6.	Nitrogen	164-172	tropomyosin 3	Homo sapiens	193-196
10455138-7	1999	Membrane-tethered PC1 and PC2 exhibited changes in pro-domain maturation rates, N-glycosylation, and in the pH and calcium optima required for maximal enzymatic activity against a fluorogenic substrate.	Nitrogen	80-81	proprotein convertase subtilisin/kexin type 1	Mus musculus	18-21
10433951-0	1999	Effects of reactive oxygen and nitrogen metabolites on RANTES- and IL-5-induced eosinophil chemotactic activity in vitro.	Nitrogen	31-39	C-C motif chemokine ligand 5	Homo sapiens	55-61
10423365-4	1999	Simulation of the temperature-dependent spectral lineshapes reveals the existence of local anisotropic motion about the nitroxide N-O bond with a motional anisotropy tau( perpendicular)/tau( parallel) ( identical with N) approaching 2.6 at 306 K. Comparison with previous work on rigidly labeled peptides suggests that the spin label is reorienting about its side-chain tether.	Nitrogen	130-131	spindlin 1	Homo sapiens	323-327
7505459-1	1993	We recently isolated and characterized the 24 kDa and N-glycosylated 28 kDa insulin-like growth factor binding protein-4 (rIGFBP-4) from the B104s rat neuronal cell line (Endocrinology, 129 (1991) 1009-1115).	Nitrogen	54-55	insulin like growth factor binding protein 4	Homo sapiens	76-120
16861926-0	2006	Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species.	Nitrogen	0-8	ATM serine/threonine kinase	Homo sapiens	71-74
8395335-6	1993	The mRNA signal was greater in the colonic carcinoma than in paired adjacent normal colonic mucosa in 38 of 42 cases for P0 [tumor/normal (T/N) ratio = 3.0 +/- 0.3, mean +/- SE, P &lt; 0.001] (G. F. Barnard, R. J. Staniunas, S. Bao, K. Mafune, J. L. Gollan, G. D. Steele, Jr., and L. B. Chen, Cancer Res., 52: 3067-3072, 1992), in 25 of 28 cases for L18 (T/N ratio = 3.7 +/- 0.5, P &lt; 0.001), in 27 of 28 cases for L37 (T/N ratio = 5.3 +/- 0.4, P &lt; 0.001), and in 24 of 28 cases for S6 (T/N ratio = 3.1 +/- 0.5, P &lt; 0.01).	Nitrogen	6-7	ribosomal protein L18	Homo sapiens	350-353
10411908-11	1999	Our genetic analyses suggest the possibility that Cdc42p and Hsl7p compete for binding to Ste20p for pseudohyphal development when starved for nitrogen.	Nitrogen	143-151	Rho family GTPase CDC42	Saccharomyces cerevisiae S288C	50-56
8376598-1	1993	The subcellular localization of Mac-1 was determined in resting and stimulated human neutrophils after disruption by nitrogen cavitation and fractionation on two-layer Percoll density gradients.	Nitrogen	117-125	integrin subunit alpha M	Homo sapiens	32-37
16720684-5	2006	Expressed rat UGT1.1, UGT2B1, and UGT2B12 in HK293 cells catalyzed the N-glucuronidation of FOSA but at rates that were lower than those observed in rat liver microsomes.	Nitrogen	71-72	UDP glucuronosyltransferase family 2 member B17	Rattus norvegicus	22-28
8395007-5	1993	The morphologic and physiological properties caused by elm1, elm2, and elm3 mutations closely mimic pseudohyphal growth occurring in conditions of nitrogen starvation.	Nitrogen	147-155	serine/threonine protein kinase ELM1	Saccharomyces cerevisiae S288C	55-59
8395007-6	1993	Therefore, we propose that absence of ELM1, ELM2, or ELM3 function causes constitutive execution of the pseudohyphal differentiation pathway that occurs normally in conditions of nitrogen starvation.	Nitrogen	179-187	serine/threonine protein kinase ELM1	Saccharomyces cerevisiae S288C	38-42
8395007-9	1993	Gene dosage experiments also showed that pseudohyphal differentiation in response to nitrogen starvation is dependent on the product of CDC55, a putative B regulatory subunit of protein phosphatase 2A, and a synthetic phenotype was observed in elm1 cdc55 double mutants.	Nitrogen	85-93	serine/threonine protein kinase ELM1	Saccharomyces cerevisiae S288C	244-248
10406650-1	1999	In order to further explore the importance of cocaine"s bridge nitrogen atom in binding to the dopamine transporter (DAT), we have synthesized the previously known racemic 8-oxa-norcocaines 3-6 in which the nitrogen atom has been replaced by oxygen.	Nitrogen	63-71	solute carrier family 6 member 3	Homo sapiens	95-115
10406650-1	1999	In order to further explore the importance of cocaine"s bridge nitrogen atom in binding to the dopamine transporter (DAT), we have synthesized the previously known racemic 8-oxa-norcocaines 3-6 in which the nitrogen atom has been replaced by oxygen.	Nitrogen	63-71	solute carrier family 6 member 3	Homo sapiens	117-120
10406650-1	1999	In order to further explore the importance of cocaine"s bridge nitrogen atom in binding to the dopamine transporter (DAT), we have synthesized the previously known racemic 8-oxa-norcocaines 3-6 in which the nitrogen atom has been replaced by oxygen.	Nitrogen	207-215	solute carrier family 6 member 3	Homo sapiens	95-115
10406650-1	1999	In order to further explore the importance of cocaine"s bridge nitrogen atom in binding to the dopamine transporter (DAT), we have synthesized the previously known racemic 8-oxa-norcocaines 3-6 in which the nitrogen atom has been replaced by oxygen.	Nitrogen	207-215	solute carrier family 6 member 3	Homo sapiens	117-120
8347678-6	1993	ST2 proteins produced in COS7 cells and BALB/c-3T3 cells were N-glycosylated as predicted from nine putative N-glycosylation sites in its deduced amino-acid sequence.	Nitrogen	62-63	interleukin 1 receptor-like 1	Mus musculus	0-3
8347678-6	1993	ST2 proteins produced in COS7 cells and BALB/c-3T3 cells were N-glycosylated as predicted from nine putative N-glycosylation sites in its deduced amino-acid sequence.	Nitrogen	109-110	interleukin 1 receptor-like 1	Mus musculus	0-3
8346228-11	1993	Three potential N-glycosylation sites were present in canine tracheal mucin and the amino acid sequence showed homology with both human tracheal and intestinal mucins.	Nitrogen	16-17	mucin	Canis lupus familiaris	70-75
8102771-6	1993	The level of vitamin E in the heart decreased with n-3 PUFA diets, most markedly with LCn-3 PUFA.	Nitrogen	19-20	lipocalin 3	Rattus norvegicus	86-91
10344722-5	1999	RESULTS: Of 26 agents screened, BRCA1 and BRCA2 mRNA reductions were observed in both cell lines after exposure to adriamycin (ADR), camptothecin (CPT), sodium selenite (SLN), and ultraviolet radiation (UV), while nitrogen mustard (HN2) caused mRNA reduction in DU-145 but not in Tsu-Prl.	Nitrogen	214-222	BRCA1 DNA repair associated	Homo sapiens	32-37
10344722-5	1999	RESULTS: Of 26 agents screened, BRCA1 and BRCA2 mRNA reductions were observed in both cell lines after exposure to adriamycin (ADR), camptothecin (CPT), sodium selenite (SLN), and ultraviolet radiation (UV), while nitrogen mustard (HN2) caused mRNA reduction in DU-145 but not in Tsu-Prl.	Nitrogen	214-222	BRCA2 DNA repair associated	Homo sapiens	42-47
10357351-4	1999	Fluorine may enhance the anesthetic action of other moieties, such as the hydrogen atom in CHF3 (MAC = 1.60 atm), but, consistent with the notion that the fluorine atoms do not directly influence sites of anesthetic action, adding -(CF2)n moieties does not further increase potency (e.g., CHF2-CF3 MAC = 1.51 atm).	Nitrogen	6-7	integrin subunit alpha M	Homo sapiens	97-104
16720684-5	2006	Expressed rat UGT1.1, UGT2B1, and UGT2B12 in HK293 cells catalyzed the N-glucuronidation of FOSA but at rates that were lower than those observed in rat liver microsomes.	Nitrogen	71-72	UDP glucuronosyltransferase 2 family, polypeptide B35	Rattus norvegicus	34-41
10336989-5	1999	Furthermore, N-linked glycosylation of the alpha-subunit of IGF-1R was 8-fold higher in the melanoma cells.	Nitrogen	13-14	insulin like growth factor 1 receptor	Homo sapiens	60-66
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	72-73	UDP glucuronosyltransferase family 2 member B17	Rattus norvegicus	39-45
10336989-6	1999	Following addition of dolichyl phosphate to MDA231 cells, N-linked glycosylation of IGF-1R was drastically increased, which in turn was correlated to a substantial translocation of IGF-1R to the plasma membrane, as assayed by IGF-1 binding analysis and by Western blotting of plasma membrane proteins.	Nitrogen	58-59	insulin like growth factor 1 receptor	Homo sapiens	84-90
8501820-3	1993	It was postulated that estramustine phosphate (EMP), an estradiol-nitrogen mustard conjugate that binds to the nuclear matrix, might enhance the cytotoxicity of etoposide (VP-16), a topoisomerase II inhibitor that acts at the level of the nuclear matrix.	Nitrogen	66-74	host cell factor C1	Homo sapiens	172-177
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	72-73	UDP glucuronosyltransferase 2 family, polypeptide B35	Rattus norvegicus	51-58
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	162-163	UDP glucuronosyltransferase family 2 member B17	Rattus norvegicus	39-45
10382996-6	1999	Adenovirus-mediated ANP gene delivery significantly increased renal blood flow, glomerular filtration rates and urine flow as well as attenuated the elevation of blood urea nitrogen levels.	Nitrogen	173-181	natriuretic peptide A	Rattus norvegicus	20-23
8463263-8	1993	All the forms of CE are N-glycosylated with high-mannose-type oligosaccharides.	Nitrogen	24-25	cathepsin E	Homo sapiens	17-19
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	162-163	UDP glucuronosyltransferase 2 family, polypeptide B35	Rattus norvegicus	51-58
8463263-10	1993	These results suggest that the recombinant CE is initially synthesized on membrane-bound ribosomes as a N-glycosylated preproenzyme and that, after cleavage of the signal segment, the 90-kDa proenzyme is proteolytically processed to the intermediate (84 kDa) and mature (82 kDa) forms by the transport system.	Nitrogen	104-105	cathepsin E	Homo sapiens	43-45
16735126-6	2006	These data suggest that 2-O and N sulfation of heparin may be of greater importance to CCL2-heparin binding than 6-O sulfation.	Nitrogen	32-33	C-C motif chemokine ligand 2	Homo sapiens	87-91
8444852-7	1993	The glycosidase cleavage analyses suggested that DDRP 48 was mainly N-link-glycosylated.	Nitrogen	68-69	DNA damage-responsive protein 48	Saccharomyces cerevisiae S288C	49-56
10365242-4	1999	These results suggest that C-terminal regions containing potential N-glycosylation sites of hTPO are required for the secretion of hTPO into culture medium as well as expression in insect cells.	Nitrogen	67-68	thyroid peroxidase	Homo sapiens	92-96
10365242-4	1999	These results suggest that C-terminal regions containing potential N-glycosylation sites of hTPO are required for the secretion of hTPO into culture medium as well as expression in insect cells.	Nitrogen	67-68	thyroid peroxidase	Homo sapiens	131-135
16514542-11	2006	Moreover, growth on glucose induced genes for nitrogen remobilisation that are typically enhanced during developmental senescence, including the glutamine synthetase gene GLN1;4 and the nitrate transporter gene AtNRT2.5.	Nitrogen	46-54	hypothetical protein	Arabidopsis thaliana	145-165
10222064-9	1999	Taken together, these data suggested that IL-4-mediated inhibition of TNFalpha-induced monocyte HA binding was dependent not only on protein synthesis, but also on N-linked glycosylation and chondroitin-sulfate modification of either CD44 or, alternatively, another monocyte protein(s) that may regulate the ability of CD44 to bind HA.	Nitrogen	71-72	CD44 molecule (Indian blood group)	Homo sapiens	234-238
10222064-9	1999	Taken together, these data suggested that IL-4-mediated inhibition of TNFalpha-induced monocyte HA binding was dependent not only on protein synthesis, but also on N-linked glycosylation and chondroitin-sulfate modification of either CD44 or, alternatively, another monocyte protein(s) that may regulate the ability of CD44 to bind HA.	Nitrogen	71-72	CD44 molecule (Indian blood group)	Homo sapiens	319-323
7681874-4	1993	Positive responses of weight gain and nitrogen balance were observed, primarily at higher dietary protein intake, after porcine somatotropin treatment.	Nitrogen	38-46	somatotropin	Sus scrofa	128-140
16839144-0	2006	Aza-beta3-cyclohexapeptides: pseudopeptidic macrocycles with interesting conformational and configurational properties slow pyramidal nitrogen inversion in 24-membered rings!	Nitrogen	134-142	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	4-9
8094032-10	1993	These results suggest that although PMA-induced ICAM-1 expression is PKC dependent on HS 683 and SK-N-SH cells, the stimulation of ICAM-1 expression by retinoic acid and by IFN-gamma may be due to PKC inactivation at longer time points (24 h), as mimicked by 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride, staurosporine, or PKC depletion by high doses of PMA.	Nitrogen	100-101	intercellular adhesion molecule 1	Homo sapiens	48-54
10320099-4	1999	The central region of chick alpha-tectorin contains fewer potential N-glycosylation sites than that of mouse alpha-tectorin and is cleaved at two additional sites.	Nitrogen	68-69	tectorin alpha	Gallus gallus	28-42
16839144-1	2006	Among pseudopeptidic foldamers, aza-beta3-peptides have the unique property to possess nitrogen stereocenters instead of carbon stereocenters.	Nitrogen	87-95	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	36-41
10232056-16	1999	These results suggest that since no dramatic changes in the levels of protein were observed in the muscle and liver, there is an alteration in glutaminase and glutamine synthetase activity in order to maintain nitrogen metabolism in the initial phase of hypoxic exposure.	Nitrogen	210-218	glutamate-ammonia ligase	Rattus norvegicus	159-179
10229326-0	1999	N-glycosylation of glucose transporter-1 (Glut-1) is associated with increased transporter affinity for glucose in human leukemic cells.	Nitrogen	0-1	solute carrier family 2 member 1	Homo sapiens	19-40
10229326-0	1999	N-glycosylation of glucose transporter-1 (Glut-1) is associated with increased transporter affinity for glucose in human leukemic cells.	Nitrogen	0-1	solute carrier family 2 member 1	Homo sapiens	42-48
10229326-1	1999	To elucidate the role of N-glycosylation in the functional activity of the universal glucose transporter, Glut-1, we investigated effects of the N-glycosylation inhibitor, tunicamycin, on glucose transport by human leukemic cell lines K562, U937 and HL60.	Nitrogen	25-26	solute carrier family 2 member 1	Homo sapiens	106-112
10229326-1	1999	To elucidate the role of N-glycosylation in the functional activity of the universal glucose transporter, Glut-1, we investigated effects of the N-glycosylation inhibitor, tunicamycin, on glucose transport by human leukemic cell lines K562, U937 and HL60.	Nitrogen	145-146	solute carrier family 2 member 1	Homo sapiens	106-112
10229326-10	1999	These results suggest that in leukemic cells N-glycosylation of Glut-1 plays an important role in maintaining its structure and functional integration.	Nitrogen	45-46	solute carrier family 2 member 1	Homo sapiens	64-70
16839144-4	2006	Both crystal structures and spectroscopic data establish that aza-beta3-cyclohexapeptides adopt a highly organized conformation where the relative configuration of chiral nitrogen atoms is alternated.	Nitrogen	171-179	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	66-71
16644726-3	2006	Feeding rats a diet containing n-3 PUFA or WY14643 suppressed hepatic mRNA(L-PK) but did not suppress hepatic ChREBP or HNF-4alpha nuclear abundance.	Nitrogen	5-6	pyruvate kinase L/R	Rattus norvegicus	75-79
10027866-2	1999	Two major polymorphic forms of human FMO3 were studied, and the results suggested preferential N-oxygenation by only one of the two enzymes.	Nitrogen	95-96	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	37-41
16894785-5	2006	From these results, the two N-H hydrogens of the amide tethers of CSP 1, the carbonyl oxygen of the amide group of analytes, and the nitro group on the benzoyl group of analytes were concluded to play significant roles in chiral recognition.	Nitrogen	28-29	regulator of calcineurin 1	Homo sapiens	66-71
10225275-3	1999	Inhibition of N-linked glycosylation by tunicamycin revealed that NS1 synthesised in MVE-infected C6/36 cells was derived from two polypeptide backbones of 39 kDa (NS1(o)) and 47 kDa (NS1").	Nitrogen	14-15	influenza virus NS1A binding protein	Homo sapiens	66-69
16601115-6	2006	Strikingly, core sugars for one of the two N-linked glycosylation sites of cystatin F are well ordered, and their conformation and interactions with the protein indicate that this unique feature of cystatin F may modulate its inhibitory properties, in particular its reduced affinity toward asparaginyl endopeptidase compared with other cystatins.	Nitrogen	43-44	cystatin F	Homo sapiens	75-85
9990022-5	1999	In the endoplasmic reticulum of either LoVo or HK293 cells, proSKI-1 is processed into two membrane-bound forms of SKI-1 (120 and 106 kDa) differing by the nature of their N-glycosylation.	Nitrogen	172-173	membrane bound transcription factor peptidase, site 1	Homo sapiens	63-68
16601115-6	2006	Strikingly, core sugars for one of the two N-linked glycosylation sites of cystatin F are well ordered, and their conformation and interactions with the protein indicate that this unique feature of cystatin F may modulate its inhibitory properties, in particular its reduced affinity toward asparaginyl endopeptidase compared with other cystatins.	Nitrogen	43-44	cystatin F	Homo sapiens	198-208
10215318-9	1999	Furthermore, this study shows that megalin carries N-glycosidically linked hybrid and complex-type oligosaccharides terminating with sialic acid.	Nitrogen	51-52	LDL receptor related protein 2	Rattus norvegicus	35-42
16759133-6	2006	The major result of this study is the identification of intramolecular interactions, whether it is at B3LYP/cc-pVDZ or at MP2/cc-pVDZ, as the dominant stabilizing factor for the large all-nitrogen cage.	Nitrogen	188-196	tryptase pseudogene 1	Homo sapiens	122-125
9922258-1	1999	The nitrogen assimilation control protein (NAC) from Klebsiella aerogenes or Escherichia coli (NACK or NACE, respectively) is a transcriptional regulator that is both necessary and sufficient to activate transcription of the histidine utilization (hut) operon and to repress transcription of the glutamate dehydrogenase (gdh) operon in K. aerogenes.	Nitrogen	4-12	glutamate dehydrogenase	Escherichia coli	296-319
9922258-1	1999	The nitrogen assimilation control protein (NAC) from Klebsiella aerogenes or Escherichia coli (NACK or NACE, respectively) is a transcriptional regulator that is both necessary and sufficient to activate transcription of the histidine utilization (hut) operon and to repress transcription of the glutamate dehydrogenase (gdh) operon in K. aerogenes.	Nitrogen	4-12	glutamate dehydrogenase	Escherichia coli	321-324
16713180-6	2006	Feeding an n-3 PUFA diet to rats with DP upregulated IL-10 mRNA in the pancreas and IL-4 and IL-10 mRNA in the spleen.	Nitrogen	5-6	interleukin 10	Rattus norvegicus	53-58
9973386-6	1999	To determine how env peptides are generated in the cytosol, we analyzed the processing of two TAP1/2-dependent epitopes containing N-linked glycosylation sites.	Nitrogen	131-132	endogenous retrovirus group K member 20	Homo sapiens	17-20
10048020-4	1999	Gan1p is required for full expression of GLN1, GDH2 and also other nitrogen utilization genes, including GAP1, PUT4, MEP2 and GDH1.	Nitrogen	67-75	Hfi1p	Saccharomyces cerevisiae S288C	0-5
10048020-4	1999	Gan1p is required for full expression of GLN1, GDH2 and also other nitrogen utilization genes, including GAP1, PUT4, MEP2 and GDH1.	Nitrogen	67-75	ammonium permease MEP2	Saccharomyces cerevisiae S288C	117-121
16713180-6	2006	Feeding an n-3 PUFA diet to rats with DP upregulated IL-10 mRNA in the pancreas and IL-4 and IL-10 mRNA in the spleen.	Nitrogen	5-6	interleukin 10	Rattus norvegicus	93-98
10048020-5	1999	The extent to which Gan1p is required, however, varies according to the gene and to the nitrogen source available.	Nitrogen	88-96	Hfi1p	Saccharomyces cerevisiae S288C	20-25
10048020-8	1999	The contribution of Gan1p to gene expression is also influenced by the nitrogen status of the cell.	Nitrogen	71-79	Hfi1p	Saccharomyces cerevisiae S288C	20-25
16774373-2	2006	This approach is based on spatially controlling the reaction of nitrogen gas with the surface atoms of a tungsten tip in a field ion microscope (FIM).	Nitrogen	64-72	TOR signaling pathway regulator	Homo sapiens	114-117
10048020-10	1999	Ada1/Gan1p thus represents the first reported case of an accessory protein (a co-activator) linking the GATA-binding proteins Gln3p and Nil1p, mediating nitrogen-regulated transcription, to the basal transcription machinery.	Nitrogen	153-161	Hfi1p	Saccharomyces cerevisiae S288C	0-4
10048020-10	1999	Ada1/Gan1p thus represents the first reported case of an accessory protein (a co-activator) linking the GATA-binding proteins Gln3p and Nil1p, mediating nitrogen-regulated transcription, to the basal transcription machinery.	Nitrogen	153-161	Hfi1p	Saccharomyces cerevisiae S288C	5-10
10199594-4	1999	Among the hepatic P450s, the N-demethylation of aminopyrine was catalysed most efficiently by CYP2C19, followed by CYP2C8, 2D6, 2C18 and 1A2, whereas the activity with CYP2E1 was negligible.	Nitrogen	29-30	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	94-101
10216914-6	1999	Key features of mouse ZP3, including the number and location of cysteine and proline residues and N-linked glycosylation sites, were also conserved in the rat homologue.	Nitrogen	98-99	zona pellucida glycoprotein 3	Mus musculus	22-25
9882513-5	1999	We investigated whether MVA synthesis and N-linked glycosylation could be involved in regulation of the expression of the EWS/FLI-1 fusion protein, which in fact contains four potential sites for N-linked glycosylation.	Nitrogen	196-197	Fli-1 proto-oncogene, ETS transcription factor	Homo sapiens	126-131
9882513-13	1999	Taken together, our data suggest that the regulatory role of N-linked glycosylation in the expression of the EWS/FLI-1 fusion protein is important for growth of Ewing"s sarcoma cells.	Nitrogen	61-62	Fli-1 proto-oncogene, ETS transcription factor	Homo sapiens	113-118
10435119-1	1999	Polyunsaturated fatty acids of omega-3 series (omega-3 or n-3 PUFA), especially long chain EPA and DHA, exert strong positive influence on human health.	Nitrogen	5-6	pumilio RNA binding family member 3	Homo sapiens	62-66
16616004-2	2006	Our new model suggests three key interactions such that (1) a protonated nitrogen of the channel blocker forms a hydrogen bond with the carbonyl oxygen of HERG residue T623; (2) an aromatic moiety of the channel blocker makes a pi-pi interaction with the aromatic ring of HERG residue Y652; and (3) a hydrophobic group of the channel blocker forms a hydrophobic interaction with the benzene ring of HERG residue F656.	Nitrogen	73-81	potassium voltage-gated channel subfamily H member 2	Homo sapiens	155-159
9834126-4	1998	M-CSF not only increased the levels of p26 HRF mRNA and protein, but also stimulated the secretion of an N-glycosylated p26 HRF with a m.w.	Nitrogen	49-50	colony stimulating factor 1 (macrophage)	Mus musculus	0-5
16616004-2	2006	Our new model suggests three key interactions such that (1) a protonated nitrogen of the channel blocker forms a hydrogen bond with the carbonyl oxygen of HERG residue T623; (2) an aromatic moiety of the channel blocker makes a pi-pi interaction with the aromatic ring of HERG residue Y652; and (3) a hydrophobic group of the channel blocker forms a hydrophobic interaction with the benzene ring of HERG residue F656.	Nitrogen	73-81	potassium voltage-gated channel subfamily H member 2	Homo sapiens	272-276
16616004-2	2006	Our new model suggests three key interactions such that (1) a protonated nitrogen of the channel blocker forms a hydrogen bond with the carbonyl oxygen of HERG residue T623; (2) an aromatic moiety of the channel blocker makes a pi-pi interaction with the aromatic ring of HERG residue Y652; and (3) a hydrophobic group of the channel blocker forms a hydrophobic interaction with the benzene ring of HERG residue F656.	Nitrogen	73-81	potassium voltage-gated channel subfamily H member 2	Homo sapiens	272-276
16616004-3	2006	The previous model assumes two interactions such that (1) a protonated nitrogen of the channel blocker forms a cation-pi interaction with the aromatic ring of HERG residue Y652; and (2) a hydrophobic group of the channel blocker forms a hydrophobic interaction with the benzene ring of HERG residue F656.	Nitrogen	71-79	potassium voltage-gated channel subfamily H member 2	Homo sapiens	159-163
9751793-1	1998	Previously, treatment of Tamm-Horsfall glycoprotein (THp) from different donors with endo-beta-galactosidase has been shown to liberate a tetra- and a Sd(a)-active pentasaccharide, concluding the presence of N-linked carbohydrate chains containing additional N -acetyllactosamine units.	Nitrogen	208-209	uromodulin	Homo sapiens	53-56
16616004-3	2006	The previous model assumes two interactions such that (1) a protonated nitrogen of the channel blocker forms a cation-pi interaction with the aromatic ring of HERG residue Y652; and (2) a hydrophobic group of the channel blocker forms a hydrophobic interaction with the benzene ring of HERG residue F656.	Nitrogen	71-79	potassium voltage-gated channel subfamily H member 2	Homo sapiens	286-290
9791119-1	1998	GATA family proteins Gln3p, Gat1p, Dal80p, and Deh1p mediate the regulation of nitrogen catabolite repression (NCR)-sensitive gene expression in Saccharomyces cerevisiae.	Nitrogen	79-87	Dal80p	Saccharomyces cerevisiae S288C	35-41
16556605-0	2006	Posttranslational N-myristoylation is required for the anti-apoptotic activity of human tGelsolin, the C-terminal caspase cleavage product of human gelsolin.	Nitrogen	18-19	gelsolin	Homo sapiens	148-156
9791124-8	1998	Under nitrogen-limiting conditions, SNZ1 mRNAs accumulate in tryptophan, adenine, and uracil auxotrophs but not in prototrophic strains, indicating that induction occurs in response to the limitation of specific nutrients.	Nitrogen	6-14	pyridoxine biosynthesis protein SNZ1	Saccharomyces cerevisiae S288C	36-40
9751510-10	1998	Complete inhibition of hTPO N-glycosylation with tunicamycin led to a 95% decrease in hTPO at the plasma membrane and, thus, to a decrease in enzymatic activity at the cell surface, emphasizing the role of N-glycans in the intracellular trafficking of hTPO.	Nitrogen	28-29	thyroid peroxidase	Homo sapiens	23-27
9751510-10	1998	Complete inhibition of hTPO N-glycosylation with tunicamycin led to a 95% decrease in hTPO at the plasma membrane and, thus, to a decrease in enzymatic activity at the cell surface, emphasizing the role of N-glycans in the intracellular trafficking of hTPO.	Nitrogen	28-29	thyroid peroxidase	Homo sapiens	86-90
9751510-10	1998	Complete inhibition of hTPO N-glycosylation with tunicamycin led to a 95% decrease in hTPO at the plasma membrane and, thus, to a decrease in enzymatic activity at the cell surface, emphasizing the role of N-glycans in the intracellular trafficking of hTPO.	Nitrogen	28-29	thyroid peroxidase	Homo sapiens	86-90
16556605-4	2006	In this study, to analyze the posttranslational N-myristoylation of gelsolin during apoptosis, metabolic labeling of gelsolin and its caspase cleavage products expressed in COS-1 cells with [3H]myristic acid was performed.	Nitrogen	48-49	gelsolin	Homo sapiens	68-76
16516472-0	2006	Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands.	Nitrogen	37-38	solute carrier family 18 member A3	Homo sapiens	77-112
9820620-6	1998	This mRNA encodes a putative 25 K protein of 219 amino acids in length, having the first 124 amino acids and, thus, two and a half structural alpha-helices in common with hGH-V.hGH-Vdelta4 has lost the N-glycosylation site at Asn 140 of hGH-V, but acquires a novel site at position 148 as well as a cystein-rich domain in the 65 carboxyl-terminal amino acids, potentially involved in multiple disulfide-bridge formation.	Nitrogen	7-8	growth hormone 2	Homo sapiens	171-176
9820620-6	1998	This mRNA encodes a putative 25 K protein of 219 amino acids in length, having the first 124 amino acids and, thus, two and a half structural alpha-helices in common with hGH-V.hGH-Vdelta4 has lost the N-glycosylation site at Asn 140 of hGH-V, but acquires a novel site at position 148 as well as a cystein-rich domain in the 65 carboxyl-terminal amino acids, potentially involved in multiple disulfide-bridge formation.	Nitrogen	7-8	growth hormone 2	Homo sapiens	177-182
9877101-9	1998	By using 3H-glucosamine as a marker of N-glycosylation, its incorporation into tyrosinase and LAMP-1 was found to be elevated in hybrids, suppressed by N-glycosylation inhibitors, and stimulated by MSH to a greater degree in hybrids compared to parental cells.	Nitrogen	152-153	lysosomal-associated membrane protein 1	Mus musculus	94-100
16674666-7	2006	The three-dimensional model revealed that porcine SPARC contains a single N-linked glycosylation at N113, seven intramolecular disulfide bridges, and assembles into dimers.	Nitrogen	74-75	secreted protein acidic and cysteine rich	Homo sapiens	50-55
9877101-10	1998	These results indicate N-glycosylation as an important regulatory pathway for MSH-induced melanogenesis and further suggest that altered N-linked glycosylation may be an underlying mechanism for regulation of both melanogenesis and metastasis in macrophage x melanoma hybrids.	Nitrogen	23-24	msh homeobox 1	Mus musculus	78-81
9877101-10	1998	These results indicate N-glycosylation as an important regulatory pathway for MSH-induced melanogenesis and further suggest that altered N-linked glycosylation may be an underlying mechanism for regulation of both melanogenesis and metastasis in macrophage x melanoma hybrids.	Nitrogen	137-138	msh homeobox 1	Mus musculus	78-81
9753616-5	1998	STC2 has a conserved N-glycosylation site and is rich in cysteines as is the case with other stanniocalcins.	Nitrogen	21-22	stanniocalcin 2	Homo sapiens	0-4
9724546-4	1998	The local mobility of reduced and oxidized cytochrome b5 turned out to be significantly different; 28 backbone nitrogens of the oxidized form were shown to participate in a conformational exchange process, while this number dropped to 12 in the reduced form.	Nitrogen	111-120	cytochrome b5 type A	Rattus norvegicus	43-56
9724546-5	1998	The correlation time, tauex, for the exchange processes could be determined for 21 and 9 backbone nitrogens for oxidized and reduced cytochrome b5, respectively, with their values ranging between 70 and 280 microseconds.	Nitrogen	98-107	cytochrome b5 type A	Rattus norvegicus	133-146
7678995-6	1993	The results show that the SCF has N-linked and O-linked carbohydrate and corresponds to the soluble form, at or about 165 amino acids in length.	Nitrogen	34-35	KIT ligand	Homo sapiens	26-29
8572914-0	1993	Investigations on the influence of Clenbuterol and recombinant porcine somatotropin on nitrogen and energy metabolism in growing pigs.	Nitrogen	87-95	somatotropin	Sus scrofa	71-83
8420826-3	1993	The A15 gene codes for a protein of 244 amino acids which contains four potential transmembrane domains and four possible N-linked glycosylation sites.	Nitrogen	122-123	immunoglobulin kappa variable 1-32 (pseudogene)	Homo sapiens	4-7
8416910-0	1993	Regulatory circuit for responses of nitrogen catabolic gene expression to the GLN3 and DAL80 proteins and nitrogen catabolite repression in Saccharomyces cerevisiae.	Nitrogen	36-44	Dal80p	Saccharomyces cerevisiae S288C	87-92
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	arginine permease CAN1	Saccharomyces cerevisiae S288C	44-48
8416910-1	1993	We demonstrate that expression of the UGA1, CAN1, GAP1, PUT1, PUT2, PUT4, and DAL4 genes is sensitive to nitrogen catabolite repression.	Nitrogen	105-113	allantoin permease	Saccharomyces cerevisiae S288C	78-82
9698372-4	1998	N-G91 and N-E226 retained peptidase activities against small unstructured peptides that were stimulated, to near-wild-type levels, by the Ms-Lon substrate protein alpha-casein.	Nitrogen	0-1	putative ATP-dependent Lon protease	Escherichia coli	141-144
16524873-0	2006	Phosphoenolpyruvate carboxylase plays a crucial role in limiting nitrogen fixation in Lotus japonicus nodules.	Nitrogen	65-73	LjPEPC1	Lotus japonicus	0-31
9753780-11	1998	TCH4 is glycosylated in vivo; glycosidases that remove N-linked glycosylation eliminated 98% of the XET activity.	Nitrogen	55-56	Xyloglucan endotransglucosylase/hydrolase family protein	Arabidopsis thaliana	0-4
8437574-5	1993	The homozygous nir1 mutant could be maintained to flowering in liquid culture with either glutamine or ammonium as sole nitrogen source, but died within 14 days after transfer to compost.	Nitrogen	120-128	Nir1	Hordeum vulgare	15-19
16524873-1	2006	Phosphoenolpyruvate carboxylase (PEPC, EC 4.1.1.31) is believed to play a significant role in supporting nitrogen fixation via anaplerotic CO2 fixation for recycling carbon in nodules.	Nitrogen	105-113	LjPEPC1	Lotus japonicus	0-31
9649619-5	1998	The rhECP described here is N-glycosylated, as is native ECP, and has approximately 100-fold more ribonuclease activity than non-glycosylated rhECP prepared in bacteria.	Nitrogen	28-29	ribonuclease A family member 3	Homo sapiens	6-9
16524873-1	2006	Phosphoenolpyruvate carboxylase (PEPC, EC 4.1.1.31) is believed to play a significant role in supporting nitrogen fixation via anaplerotic CO2 fixation for recycling carbon in nodules.	Nitrogen	105-113	LjPEPC1	Lotus japonicus	33-37
9642297-4	1998	Our results demonstrate that sequential proteolytic cleavage within the ectodomain of the 50-kDa pro-AR form leads to release of a predominant N-glycosylated 43-kDa soluble AR, as well as the appearance of other cellular and soluble AR forms.	Nitrogen	143-144	amphiregulin	Homo sapiens	101-103
1460006-1	1992	We previously showed that the zinc metalloenzyme carbonic anhydrases (CA I and II isozymes) bind "neutral" amides and related compounds as anions through coordination of their deprotonated amide nitrogen to the active site zinc (Rogers, J. I., Mukherjee, J., and Khalifah, R. G. (1987) Biochemistry 26, 5672-5679).	Nitrogen	195-203	carbonic anhydrase 1	Homo sapiens	70-74
16524873-5	2006	In nodules of Asppc plants, PEPC activity was reduced to about 10% of that of non-transformants and the plants showed typical nitrogen-deficient symptoms without a supply of nitrogen nutrient, and returned to normal growth when nitrate was supplied at 2.5 mM.	Nitrogen	126-134	LjPEPC1	Lotus japonicus	28-32
9649520-12	1998	Pbn1p is N-glycosylated in its amino-terminal domain, indicating a lumenal orientation despite the lack of a signal sequence.	Nitrogen	9-10	Pbn1p	Saccharomyces cerevisiae S288C	0-5
16524873-5	2006	In nodules of Asppc plants, PEPC activity was reduced to about 10% of that of non-transformants and the plants showed typical nitrogen-deficient symptoms without a supply of nitrogen nutrient, and returned to normal growth when nitrate was supplied at 2.5 mM.	Nitrogen	174-182	LjPEPC1	Lotus japonicus	28-32
16524873-10	2006	The data are discussed in terms of a role for PEPC in the carbon/nitrogen metabolic flux in nodules.	Nitrogen	65-73	LjPEPC1	Lotus japonicus	46-50
16372350-0	2006	A dynamic N-capping motif in cytochrome b5: evidence for a pH-controlled conformational switch.	Nitrogen	10-11	cytochrome b5 type A	Homo sapiens	29-42
9796244-7	1998	Percentage changes from baseline of both PRA and RBP were significantly correlated with nitrogen balance (p = 0.01 and p = 0.009); while no significant correlation was observed between changes of rapid turnover proteins and CRP (p = 0.72 and p = 0.10).	Nitrogen	88-96	retinol binding protein 4	Homo sapiens	49-52
1281868-5	1992	The additional domain adds a number of potential N- and O-linked glycosylation sites and two proteolysis sites to this form of CD44.	Nitrogen	49-50	CD44 molecule (Indian blood group)	Homo sapiens	127-131
1293888-6	1992	The upstream regulatory region of DAL4 contains all of the characterized cis-acting elements previously reported for inducible allantoin pathway genes: six sequences homologous to UASNTR, the element responsible for nitrogen catabolite repression-sensitive activation of allantoin pathway gene expression, and two sequences homologous to the cis-acting element responsible for inducer-responsiveness of the allantoin pathway genes, UIS.	Nitrogen	216-224	allantoin permease	Saccharomyces cerevisiae S288C	34-38
16569053-7	2006	On the basis of the role of shikimic acid and PCA in the regulation of PEPC, as potent competitive inhibitors, this additional effect provoked by glyphosate on 5-enolpyruvylshikimic-3-phosphate synthase enzyme (EPSPS; EC 2.5.1.19) inhibition would divert most PEP into the shikimate pathway, depriving energy substrates to bacteroids to maintain nitrogen fixation.	Nitrogen	346-354	phosphoenolpyruvate carboxykinase 1	Homo sapiens	71-75
1429698-5	1992	Two of the eight ordered waters in I-FABP:oleate are part of a hydrogen bond network that includes the carboxylate of oleate, the guanidinium group of Arg106, the nitrogen of the indole group of Trp82, and the side chain of Gln115.	Nitrogen	163-171	fatty acid binding protein 2	Rattus norvegicus	35-41
1423830-8	1992	Quantitative differences in adduct formation between IQ and N-acetyl-IQ indicated that metabolic activation of these arylamines preferentially occurs by P4501A2-catalyzed N-hydroxylation followed by O-acetylation mediated through NAT1 and/or NAT2.	Nitrogen	60-61	N-acetyltransferase 2	Homo sapiens	242-246
1459173-9	1992	CONCLUSIONS: Dietary supplementation with n-3 PUFA in patients with rheumatoid arthritis improved two out of six patient reported disease parameters.	Nitrogen	29-30	pumilio RNA binding family member 3	Homo sapiens	46-50
9616184-4	1998	We show that human UGT1A3, transiently expressed in human embryonic kidney 293 cells, also catalyzes the N-glucuronidation of primary, secondary, and tertiary amine substrates, such as 4-aminobiphenyl, diphenylamine, and cyproheptadine.	Nitrogen	105-106	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	19-25
9585559-2	1998	In the bovine Hsc70 ATPase fragment, mutation of cysteine 17 or aspartic acid 206 to lysine potentially allows the replacement of an active site potassium ion with the epsilon-amino nitrogen.	Nitrogen	182-190	heat shock protein family A (Hsp70) member 8	Bos taurus	14-26
9630843-14	1998	Increased productions of CA N-demethylation metabolites (TB, PX, and TP) are, however, catalyzed by the increased activities of CYP1A2 and FMO which are associated uniquely with the MC-microsomes.	Nitrogen	28-29	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	128-134
1429287-16	1992	Nitrogen retained (grams) per gram of nitrogen intake from indispensable AA was greater (P less than .01) for IIP than for either IFP or WFIP.	Nitrogen	0-8	Internal fat percentage	Sus scrofa	130-133
16569053-7	2006	On the basis of the role of shikimic acid and PCA in the regulation of PEPC, as potent competitive inhibitors, this additional effect provoked by glyphosate on 5-enolpyruvylshikimic-3-phosphate synthase enzyme (EPSPS; EC 2.5.1.19) inhibition would divert most PEP into the shikimate pathway, depriving energy substrates to bacteroids to maintain nitrogen fixation.	Nitrogen	346-354	progestagen associated endometrial protein	Homo sapiens	71-74
16630058-6	2006	IB of human choroid plexus and CSF using TAp73-specific antibodies revealed the presence of a approximately 90-kDa protein whose molecular weight was reduced after N-deglycosylation, suggesting that glycosylated TAp73 is exported into the CSF.	Nitrogen	164-165	transformation related protein 73	Mus musculus	41-46
1383128-6	1992	The use of inhibitor of N-linked glycosylation tunicamicyn has demonstrated that the mAbs bind to epitopes localized in the protein core of gp185HER-2.	Nitrogen	24-25	glycoprotein 2 (zymogen granule membrane)	Mus musculus	140-150
9536088-2	1998	We show here that mutations in the human flavin-containing monooxygenase isoform 3 gene ( FMO3 ) impair N -oxygenation of xenobiotics and are responsible for the trimethylaminuria phenotype.	Nitrogen	104-105	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	90-94
9575816-10	1998	These findings indicate that a 178-kDa glucose-inducible phosphoprotein binds to an (ACCCC)n-containing sequence in the 3"-UTR of the FAS mRNA within the same time frame that glucose stabilizes the FAS message.	Nitrogen	8-9	fatty acid synthase	Homo sapiens	134-137
16472779-8	2006	In addition, both AtGLN1;1 and AtCRK3 could be induced by natural or artificially induced leaf senescence, implying that such interaction may be involved in the regulation of nitrogen remobilization during leaf senescence.	Nitrogen	175-183	hypothetical protein	Arabidopsis thaliana	18-26
9518462-3	1998	The hIL-17 produced in Pichia had the correct N-terminus of natural mature hIL-17 and a glycosylation pattern similar to hIL-17 produced in mammalian cells; both Pichia and human cells add approximately 5 kDa of sugars via N-linked glycosylation and both express a mixture of the glycosylated and nonglycosylated forms.	Nitrogen	46-47	interleukin 17A	Homo sapiens	4-10
1495013-0	1992	N-methylated analogs of Ac[Nle28,31]CCK(26-33): synthesis, activity, and receptor selectivity.	Nitrogen	0-1	cholecystokinin	Cavia porcellus	36-39
16407250-6	2006	Most interestingly, Hpocr1Delta showed a severe defect in the O-linked glycosylation of extracellular chitinase, representing HpOCR1 as a novel member of the OCH1 family implicated in both N- and O-linked glycosylation.	Nitrogen	189-190	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	158-162
1388517-1	1992	The effects of resorcinolic lipids (5-n-alk(en)ylresorcinols) isolated from cereal grains on the phospholipase A2 catalyzed hydrolysis of phospholipid vesicles were examined.	Nitrogen	22-23	ALK receptor tyrosine kinase	Homo sapiens	40-43
12515161-8	1998	In addition, a N-glycosylation site was found in the NS3 region of all the six isolates.	Nitrogen	15-16	KRAS proto-oncogene, GTPase	Homo sapiens	53-56
16337118-1	2006	Exploiting the SAR of the known pyrrole derivatives, a new class of mGluR1 antagonists was developed through a cyclization of the C-2 position on the pyrrole N-1 nitrogen.	Nitrogen	162-170	complement C2	Homo sapiens	130-133
9526071-1	1998	Clusterin is a N-glycosylated sialoglycoprotein present in rat brain cells.	Nitrogen	15-16	clusterin	Rattus norvegicus	0-9
1594597-4	1992	In patient ARC-21, a methionine-to-threonine substitution at position 1772 in the factor VIII light chain creates a potential new N-glycosylation site at asparagine-1770.	Nitrogen	130-131	actin related protein 2/3 complex subunit 3	Homo sapiens	11-17
16272405-3	2006	The results indicate that CYP1A2 and CYP3A4 are the main enzymes responsible for 5-sulfoxidation and N-demethylation (34-52%), whereas CYP2D6 is the basic enzyme that catalyzes mono-2- and di-2-sulfoxidation of thioridazine in human liver (49 and 64%, respectively).	Nitrogen	101-102	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	26-32
1525858-1	1992	The UGA43 gene of Saccharomyces cerevisiae is required for repression of inducible genes involved in the utilization of 4-aminobutyric acid (GABA) or urea as nitrogen sources.	Nitrogen	158-166	Dal80p	Saccharomyces cerevisiae S288C	4-9
1525858-8	1992	On "poor" nitrogen sources, UGA43 transcripts are measured at high levels whereas they are nearly undetectable in conditions of nitrogen catabolite repression.	Nitrogen	10-18	Dal80p	Saccharomyces cerevisiae S288C	28-33
1525858-8	1992	On "poor" nitrogen sources, UGA43 transcripts are measured at high levels whereas they are nearly undetectable in conditions of nitrogen catabolite repression.	Nitrogen	128-136	Dal80p	Saccharomyces cerevisiae S288C	28-33
1525858-9	1992	The levels measured on "poor" nitrogen sources are further increased in uga43 mutant cells, suggesting that UGA43 exerts negative autoregulation.	Nitrogen	30-38	Dal80p	Saccharomyces cerevisiae S288C	72-77
1525858-9	1992	The levels measured on "poor" nitrogen sources are further increased in uga43 mutant cells, suggesting that UGA43 exerts negative autoregulation.	Nitrogen	30-38	Dal80p	Saccharomyces cerevisiae S288C	108-113
9442051-8	1998	The defect in spermidine transport was more pronounced in NH4(+)- than proline-grown npr1 cells, suggesting that NPR1 protects against nitrogen catabolite repression of polyamine uptake activity.	Nitrogen	135-143	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	113-117
9442051-9	1998	These results suggest that (a) the polyamine carrier is an unstable protein subject to down-regulation by spermidine via a process involving ligand inactivation followed by endocytosis and that (b) NPR1 expression fully prevents nitrogen catabolite repression of polyamine transport, unlike the role predicted for that gene by the inactivation/reactivation model proposed for other nitrogen permeases.	Nitrogen	229-237	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	198-202
9512652-3	1998	A low molecular weight, secretory PLA2 was identified by enzymatic activity in the cell free supernates of primed or stimulated PMN, and in PMN disrupted by nitrogen cavitation.	Nitrogen	157-165	phospholipase A2 group IIA	Homo sapiens	34-38
10353717-1	1998	Band 3, the human erythrocyte anion exchanger (AE1), and the glucose transporter (GLUT1) proteins each contain a single site of N-glycosylation that is heterogeneously glycosylated.	Nitrogen	128-129	solute carrier family 2 member 1	Homo sapiens	82-87
1548748-9	1992	A polyclonal anti-IAPE env antiserum, raised against a bacterial IAPE-env fusion protein, specifically detects N-glycosylated env proteins of 91 kDa or less in cell lines positive for IAPE mRNA.	Nitrogen	111-112	endogenous retrovirus group K member 20	Homo sapiens	23-26
1548748-9	1992	A polyclonal anti-IAPE env antiserum, raised against a bacterial IAPE-env fusion protein, specifically detects N-glycosylated env proteins of 91 kDa or less in cell lines positive for IAPE mRNA.	Nitrogen	111-112	endogenous retrovirus group K member 20	Homo sapiens	70-73
1548748-9	1992	A polyclonal anti-IAPE env antiserum, raised against a bacterial IAPE-env fusion protein, specifically detects N-glycosylated env proteins of 91 kDa or less in cell lines positive for IAPE mRNA.	Nitrogen	111-112	endogenous retrovirus group K member 20	Homo sapiens	70-73
1548748-11	1992	After inhibition of N-glycosylation, env proteins in the size predicted from the env gene sequence or smaller are present.	Nitrogen	20-21	endogenous retrovirus group K member 20	Homo sapiens	37-40
1548748-11	1992	After inhibition of N-glycosylation, env proteins in the size predicted from the env gene sequence or smaller are present.	Nitrogen	20-21	endogenous retrovirus group K member 20	Homo sapiens	81-84
9459121-5	1998	These results suggest that there are at least two isozymes for N-acetylation in the human epidermic and NAT2 may be affected by UVB irradiation.	Nitrogen	63-64	N-acetyltransferase 2	Homo sapiens	104-108
16402830-9	2006	The chelate Pd-imidazole N-3 bond is longer when the heterocyclic nitrogen is hindered by an adjacent tert-butyl group at C-4 (comparing 5a-PhI and 5b-PhI).	Nitrogen	66-74	complement C4A (Rodgers blood group)	Homo sapiens	122-125
9440817-5	1998	This finding was based on TM-3 mutation E124Q, which eliminated the counter-ion to the shared basic N+ group of all GHSs and resulted in a nonfunctional receptor.	Nitrogen	100-102	tropomyosin 3	Homo sapiens	26-30
1736898-3	1992	On the basis of cDNA sequence analysis, Xenopus SPARC has a core Mr of 32643, with one potential N-glycosylation site.	Nitrogen	18-19	secreted protein, acidic, cysteine-rich (osteonectin) S homeolog	Xenopus laevis	48-53
16344471-11	2005	Therefore, our results implicate reduced N signaling in the pathology of CDG IIc.	Nitrogen	41-42	solute carrier family 35 member C1	Homo sapiens	73-80
1944286-0	1991	Expression of the DAL80 gene, whose product is homologous to the GATA factors and is a negative regulator of multiple nitrogen catabolic genes in Saccharomyces cerevisiae, is sensitive to nitrogen catabolite repression.	Nitrogen	118-126	Dal80p	Saccharomyces cerevisiae S288C	18-23
1944286-1	1991	We have cloned the negative regulatory gene (DAL80) of the allantoin catabolic pathway, characterized its structure, and determined the physiological conditions that control DAL80 expression and its influence on the expression of nitrogen catabolic genes.	Nitrogen	230-238	Dal80p	Saccharomyces cerevisiae S288C	45-50
9395522-7	1997	Deglycosylation experiments, reactivity with lectins, and chromatography on concanavalin A-Sepharose indicated that corneodesmosin is N-glycosylated.	Nitrogen	134-135	corneodesmosin	Homo sapiens	116-130
1944286-2	1991	Disruption of the DAL80 gene demonstrated that it regulates multiple nitrogen catabolic pathways.	Nitrogen	69-77	Dal80p	Saccharomyces cerevisiae S288C	18-23
16037491-1	2005	Defects in the biosynthesis of N- and core 1 O-glycans may be found by isoelectric focusing (IEF) of plasma transferrin and apolipoprotein C-III (apoC-III).	Nitrogen	31-32	apolipoprotein C3	Homo sapiens	124-144
1944286-4	1991	DAL80 transcription was itself highly sensitive to nitrogen catabolite repression (NCR), and its promoter contained 12 sequences homologous to the NCR-sensitive UASNTR.	Nitrogen	51-59	Dal80p	Saccharomyces cerevisiae S288C	0-5
9360950-6	1997	Of the 14 transmembrane domains (TM) of N1 and N2, transplanting TM8-9 of N1 into N2 converted N2 from a pyrimidine- to a purine-selective transporter.	Nitrogen	47-49	tetraspanin 16	Homo sapiens	65-70
16037491-1	2005	Defects in the biosynthesis of N- and core 1 O-glycans may be found by isoelectric focusing (IEF) of plasma transferrin and apolipoprotein C-III (apoC-III).	Nitrogen	31-32	apolipoprotein C3	Homo sapiens	146-154
1922074-2	1991	Comparison of the N-linked glycosylation of Sec12p, a Sec12p-invertase hybrid protein, and a derivative of Sec12p lacking 71 carboxy-terminal amino acids showed that Sec12p is a type II membrane protein.	Nitrogen	18-19	Sar family guanine nucleotide exchange factor SEC12	Saccharomyces cerevisiae S288C	44-50
16261241-0	2005	Four-electron reduction of dinitrogen during solution disproportionation of the organodimetallic (eta-C5Me4R)2Ta2(mu-Cl)4(R = Me, Et) to a new mu-eta1,eta1-N2 complex and odd-electron organotrimetallic cluster.	Nitrogen	27-37	secreted phosphoprotein 1	Homo sapiens	146-150
2005641-10	1991	These results indicate that increased expression of ERCC1 and increased activity of 3-methyladenine-DNA glycosylase occur with the development of resistance to the nitrogen mustards in patients with CLL, suggesting a role for enhanced DNA repair in this process.	Nitrogen	164-172	N-methylpurine DNA glycosylase	Homo sapiens	84-115
9428654-1	1997	In the present study, we demonstrated that the attachment of the nonpolar isopropylic carbon chain in the nitrogen of oxamate, converted this competitive inhibitor of LDH isozymes into a powerful selective inhibitor of mouse LDH-C4.	Nitrogen	106-114	lactate dehydrogenase C	Mus musculus	225-231
9353284-0	1997	An N-linked glycosylation motif from the noncleaving luteinizing hormone receptor substituted for the homologous region (Gly367 to Glu369) of the thyrotropin receptor prevents cleavage at its second, downstream site.	Nitrogen	3-4	thyroid stimulating hormone receptor	Homo sapiens	146-166
9353284-8	1997	TSHR cleavage or noncleavage after substitution of GQE367-369 with other triplets (AAA, NQE, and NQT) was consistent with a role for N-linked glycosylation at this site.	Nitrogen	88-89	thyroid stimulating hormone receptor	Homo sapiens	0-4
16261241-0	2005	Four-electron reduction of dinitrogen during solution disproportionation of the organodimetallic (eta-C5Me4R)2Ta2(mu-Cl)4(R = Me, Et) to a new mu-eta1,eta1-N2 complex and odd-electron organotrimetallic cluster.	Nitrogen	27-37	secreted phosphoprotein 1	Homo sapiens	151-155
9353284-9	1997	In summary, our data (i) support the concept that the TSHR cleaves at two sites, (ii) relate TSHR residues GQE367-369 to cleavage at the second, downstream site, and (iii) suggest that cleavage or noncleavage at site two is related to N-linked glycosylation.	Nitrogen	235-236	thyroid stimulating hormone receptor	Homo sapiens	54-58
9353284-9	1997	In summary, our data (i) support the concept that the TSHR cleaves at two sites, (ii) relate TSHR residues GQE367-369 to cleavage at the second, downstream site, and (iii) suggest that cleavage or noncleavage at site two is related to N-linked glycosylation.	Nitrogen	235-236	thyroid stimulating hormone receptor	Homo sapiens	93-97
1704129-7	1991	The amino terminus of precerebellin contains three possible N-linked glycosylation sites.	Nitrogen	60-61	cerebellin 1 precursor	Homo sapiens	22-35
16275904-1	2005	In cells of Saccharomyces cerevisiae, using ammonia as a source of nitrogen, Gln3p is sequestered in the cytoplasm by Ure2p but enters the nucleus when the cells are shifted to a nonpreferred source of nitrogen such as proline.	Nitrogen	67-75	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	77-82
1962150-2	1991	Serial lectin affinity chromatography and N- or O-glycanase treatment to reduce antigenicity showed that CA125 contained certain N- and O-glycosylated sugar chains in the molecule, like a glycoprotein.	Nitrogen	42-43	mucin 16, cell surface associated	Homo sapiens	105-110
2090718-5	1990	Rat apoD has multiple isoelectric points between pH 4.05 and 4.37, apparently resulting from N-linked glycosylation.	Nitrogen	93-94	apolipoprotein D	Rattus norvegicus	4-8
2073375-2	1990	Both the phenyl and the adamantyl groups lie syn to the unsubstituted nitrogen of the guanidinium ion.	Nitrogen	70-78	synemin	Homo sapiens	45-48
1693564-10	1990	In summary, the present data indicate that: i) hTPO expressed in CHO cells contains N-linked, but not O-linked glycan moieties; ii) the N-linked carbohydrate is primarily of the polymannose variety; and, iii) the glycan moieties do not contribute to the hTPO epitopes in Hashimoto"s thyroiditis.	Nitrogen	84-85	thyroid peroxidase	Homo sapiens	47-51
2318146-7	1990	We conclude that 1) N-linked carbohydrates contribute about 20 kDa to the apparent mass of the GH receptor of rat adipocytes; 2) N-linked glycosylation is not required for GH receptors to be inserted into the adipocyte membrane in the proper orientation and to retain their ability to recognize and bind GH; 3) N-linked sugar chains are required for maintenance of a normal high affinity of receptors for GH; 4) N-linked carbohydrates are necessary for normal rates of internalization and processing of bound hGH.	Nitrogen	20-21	growth hormone receptor	Rattus norvegicus	95-106
2126341-2	1990	The FSH receptor (FSH-R), as predicted from the cDNA, is a single 75K polypeptide with a 348 residue extracellular domain which contains three N-linked glycosylation sites.	Nitrogen	50-51	follicle stimulating hormone receptor	Homo sapiens	4-16
2126341-2	1990	The FSH receptor (FSH-R), as predicted from the cDNA, is a single 75K polypeptide with a 348 residue extracellular domain which contains three N-linked glycosylation sites.	Nitrogen	50-51	follicle stimulating hormone receptor	Homo sapiens	18-23
24429889-1	1990	Diazotrophs, especially of genusAzospirillum were readily isolated from roots of many plants using semi-solid nitrogen free malate medium (NFM).	Nitrogen	110-118	neurofilament medium chain	Homo sapiens	139-142
2137335-6	1990	The N-terminal sequence of human renal dipeptidase showed a high degree of similarity with that of the pig enzyme, and enzymic deglycosylation revealed that the difference in size of renal dipeptidase between these two species is due almost entirely to differences in the extent of N-linked glycosylation.	Nitrogen	4-5	dipeptidase 1	Sus scrofa	183-200
2397029-3	1990	The main changes in N-glycosylation observed in confluent undifferentiated cells may be summarised as follows: 1) the conversion of high mannose into complex glycopeptides is greatly decreased; 2) this decreased conversion could be a consequence of an accumulation of Man9-8-GlcNAc2-Asn high mannose species.	Nitrogen	20-21	mannosidase alpha class 1A member 1	Homo sapiens	268-272
33973410-9	2021	Our findings suggest that the induction of miR399b in NODs could enhance nitrogen fixation and soybean growth, possibly via improving Pi uptake to achieve a better Pi-nitrogen balance to promote SNF in nodules.	Nitrogen	73-81	MIR399B	Glycine max	43-50
33973410-9	2021	Our findings suggest that the induction of miR399b in NODs could enhance nitrogen fixation and soybean growth, possibly via improving Pi uptake to achieve a better Pi-nitrogen balance to promote SNF in nodules.	Nitrogen	167-175	MIR399B	Glycine max	43-50
33771926-6	2021	Several identical CD4 polymorphisms, including the addition of N-linked glycosylation sites, were found in primate species from different genera, providing striking examples of parallel evolution.	Nitrogen	63-64	CD4 molecule	Pan troglodytes	18-21
33236627-0	2021	Electrocatalytic Water Oxidation by a Phosphorus-Nitrogen O PN3-Pincer Cobalt Complex.	Nitrogen	49-57	sodium voltage-gated channel alpha subunit 10	Homo sapiens	60-63
28902392-1	2018	Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues.	Nitrogen	156-164	protein arginine methyltransferase 7	Homo sapiens	0-36
28902392-1	2018	Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues.	Nitrogen	156-164	protein arginine methyltransferase 7	Homo sapiens	38-43
25784301-7	2015	XPS and FTIR spectra confirmed that oxygen and nitrogen atoms notably contributed to BDE-209 binding.	Nitrogen	47-55	homeobox D13	Homo sapiens	85-88
8535240-9	1995	Three putative N-glycosylation sites (Asn 63, Asn 85, and Asn 193) are present in bovine osteopontin, but sequence and mass spectrometric analysis showed that none of these asparagines were glycosylated in bovine mammary gland osteopontin.	Nitrogen	15-16	secreted phosphoprotein 1	Bos taurus	89-100
34710461-2	2022	Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN).	Nitrogen	26-34	succinate dehydrogenase complex subunit C	Homo sapiens	154-158
34710461-2	2022	Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN).	Nitrogen	26-34	succinate dehydrogenase complex subunit C	Homo sapiens	160-167
34710461-2	2022	Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN).	Nitrogen	53-61	succinate dehydrogenase complex subunit C	Homo sapiens	154-158
34710461-2	2022	Under different carbon to nitrogen (C/N) ratios, the nitrogen removal efficiency (NRE) and carbon source efficiency (CSE) of denitrification coupled with SDHC (DN-SDHC) were distinctly higher than that of denitrification alone (DN).	Nitrogen	53-61	succinate dehydrogenase complex subunit C	Homo sapiens	160-167
34710461-3	2022	Moreover, at the C/N ratios of 3.0-3.2 and 5.8-5.9, the nitrogen removal rate (NRR) of DN-SDHC was 3.6- and 1.5-fold that of DN, respectively.	Nitrogen	19-20	succinate dehydrogenase complex subunit C	Homo sapiens	90-94
34710461-3	2022	Moreover, at the C/N ratios of 3.0-3.2 and 5.8-5.9, the nitrogen removal rate (NRR) of DN-SDHC was 3.6- and 1.5-fold that of DN, respectively.	Nitrogen	56-64	succinate dehydrogenase complex subunit C	Homo sapiens	90-94
34492279-9	2022	Increased total n-3 PUFA (DHA, EPA and ALA) was significantly associated with lower IL-10 (beta = -0.667; p = 0.007) and lower total Th2 (IL-4, IL-10 and IL-13) (beta = -0.715; p = 0.036).	Nitrogen	16-17	interleukin 10	Homo sapiens	84-89
34492279-9	2022	Increased total n-3 PUFA (DHA, EPA and ALA) was significantly associated with lower IL-10 (beta = -0.667; p = 0.007) and lower total Th2 (IL-4, IL-10 and IL-13) (beta = -0.715; p = 0.036).	Nitrogen	16-17	interleukin 10	Homo sapiens	144-149
34460026-6	2022	Hypoxia/reoxygenation (H/R) cell models were established by stimulating H9c2 cells with 95% nitrogen and 5% carbon dioxide.	Nitrogen	92-100	HR, lysine demethylase and nuclear receptor corepressor	Rattus norvegicus	23-26
34614273-3	2022	Nitrogen supplementation selectively induced a mesophyll lipoxygenase (ZmLOX6), which was targeted to chloroplasts by a novel N-terminal transit peptide of 62 amino acids.	Nitrogen	0-8	linoleate 9S-lipoxygenase6	Zea mays	71-77
34714058-0	2022	Ascendancy of Nitrogen Heterocycles in the Computationally Designed Mn(I)PNN Pincer Catalysts on the Hydrogenation of Carbon Dioxide to Methanol.	Nitrogen	14-22	pinin, desmosome associated protein	Homo sapiens	73-76
34492473-0	2022	Interface engineering of MoS2@Fe(OH)3 nanoarray heterostucture: Electrodeposition of MoS2@Fe(OH)3 as N2 and H+ channels for artificial NH3 synthesis under mild conditions.	Nitrogen	101-103	general transcription factor IIE subunit 1	Homo sapiens	30-37
34492473-0	2022	Interface engineering of MoS2@Fe(OH)3 nanoarray heterostucture: Electrodeposition of MoS2@Fe(OH)3 as N2 and H+ channels for artificial NH3 synthesis under mild conditions.	Nitrogen	101-103	general transcription factor IIE subunit 1	Homo sapiens	90-97
34963193-8	2022	Based on gene set enrichment analysis, hyper-methylation of CASP1, CFH, and TTLL7 were found enriched in tumor-related KEGG terms, such as "RNA degradation", "apyruvate metabolism", and "nitrogen metabolism".	Nitrogen	187-195	tubulin tyrosine ligase like 7	Homo sapiens	76-81
34874284-1	2021	In this paper, a carbon nanofiber (CNF) hybrid nanomaterial composed of MnO-Sn cubes embedding in nitrogen-doped CNF (MnO-Sn@CNF) is synthesized through electrospinning and post-thermal reduction processes.	Nitrogen	98-106	NPHS1 adhesion molecule, nephrin	Homo sapiens	35-38
34874284-1	2021	In this paper, a carbon nanofiber (CNF) hybrid nanomaterial composed of MnO-Sn cubes embedding in nitrogen-doped CNF (MnO-Sn@CNF) is synthesized through electrospinning and post-thermal reduction processes.	Nitrogen	98-106	NPHS1 adhesion molecule, nephrin	Homo sapiens	113-116
34874284-1	2021	In this paper, a carbon nanofiber (CNF) hybrid nanomaterial composed of MnO-Sn cubes embedding in nitrogen-doped CNF (MnO-Sn@CNF) is synthesized through electrospinning and post-thermal reduction processes.	Nitrogen	98-106	NPHS1 adhesion molecule, nephrin	Homo sapiens	118-128
34882420-0	2021	Probing Magnetic Defects in Ultra-Scaled Nanowires with Optically Detected Spin Resonance in Nitrogen-Vacancy Center in Diamond.	Nitrogen	93-101	spindlin 1	Homo sapiens	75-79
34943103-5	2021	The (GT)n/(TA)n dinucleotide variations in HMOX1/UGT1A1 gene promoters, respectively, were analyzed by fragment analysis.	Nitrogen	8-9	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	49-55
9395215-2	1997	Mechanism studies indicate that I3C induces cytochromes P4501A1 and 1A2 (CYP1A1 and CYP1A2), isozymes that respectively metabolize IQ via ring hydroxylation or activate the carcinogen by N-hydroxylation.	Nitrogen	187-188	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	84-90
9336832-2	1997	For the oxidoreductase enzymes, NAD(P) functions as a cofactor in electron transfer, whereas for DT, NAD is a labile substrate in which the N-glycosidic bond between the nicotinamide ring and the N-ribose is cleaved.	Nitrogen	32-33	thioredoxin reductase 1	Homo sapiens	8-22
11669951-8	1997	The structural modifications associated with the spin change in 2 mainly consist of a large reorganization of the metal environment: the Fe-N decreases by 0.15 A (mean value) when the temperature is lowered from 290 to 139 K and a more regular shape of the [FeN(6)] octahedron is achieved through a slight modification of the trigonal deformation angle from 5.3 degrees to 3.2 degrees along with remarkable variations of the N-Fe-N angles.	Nitrogen	140-141	spindlin 1	Homo sapiens	49-53
11669951-8	1997	The structural modifications associated with the spin change in 2 mainly consist of a large reorganization of the metal environment: the Fe-N decreases by 0.15 A (mean value) when the temperature is lowered from 290 to 139 K and a more regular shape of the [FeN(6)] octahedron is achieved through a slight modification of the trigonal deformation angle from 5.3 degrees to 3.2 degrees along with remarkable variations of the N-Fe-N angles.	Nitrogen	260-261	spindlin 1	Homo sapiens	49-53
9153228-6	1997	The presence of N-linked glycosylation was shown by digestion with N-glycosidase F, which reduced the apparent molecular mass of gp-340 under reducing condition to about 300 kDa.	Nitrogen	16-17	deleted in malignant brain tumors 1	Homo sapiens	129-135
9149128-2	1997	Here we report that MDR cells are hypersensitive to the N-linked glycosylation inhibitor tunicamycin, which induces partial inhibition of GLUT-1 glycosylation and diminishes GLUT-1-mediated transport.	Nitrogen	56-57	solute carrier family 2 member 1	Homo sapiens	138-144
9149128-2	1997	Here we report that MDR cells are hypersensitive to the N-linked glycosylation inhibitor tunicamycin, which induces partial inhibition of GLUT-1 glycosylation and diminishes GLUT-1-mediated transport.	Nitrogen	56-57	solute carrier family 2 member 1	Homo sapiens	174-180
9139738-8	1997	3) gp180 is heavily N-glycosylated, since N-glycanase treatment results in a &gt;50% reduction in size.	Nitrogen	20-21	carboxypeptidase D	Mus musculus	3-8
9180275-2	1997	The expression levels of Ca-Can1p were influenced by the available nitrogen source, being almost negligible when cells were grown in the presence of ammonia.	Nitrogen	67-75	arginine permease CAN1	Saccharomyces cerevisiae S288C	28-33
9084450-5	1997	However, N-linked glycosylation of MAG does play a role in the proper folding of MAG.	Nitrogen	9-10	myelin associated glycoprotein	Homo sapiens	35-38
9084450-5	1997	However, N-linked glycosylation of MAG does play a role in the proper folding of MAG.	Nitrogen	9-10	myelin associated glycoprotein	Homo sapiens	81-84
9122262-1	1997	To determine if N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), a carboxyl group activating agent, can inactivate 5HT2c receptors, we have examined the effects of EEDQ on 5HT2c receptor-mediated responses to 5-hydroxytryptamine (5HT) in Xenopus oocytes, and on the binding of [3H]5HT to 5HT2c receptors in transfected HeLa cells.	Nitrogen	16-17	5-hydroxytryptamine receptor 2C	Homo sapiens	121-126
9074651-9	1997	These results indicated that: (a) 3,5-dichloroaniline and its metabolites can induce methemoglobin formation; (b) the N-hydroxy metabolite was the most potent inducer of hemoglobin oxidation and (c) glutathione depletion was associated with methemoglobin formation by 3,5-dichlorophenylhydroxylamine.	Nitrogen	118-119	hemoglobin subunit gamma 2	Homo sapiens	85-98
9074651-9	1997	These results indicated that: (a) 3,5-dichloroaniline and its metabolites can induce methemoglobin formation; (b) the N-hydroxy metabolite was the most potent inducer of hemoglobin oxidation and (c) glutathione depletion was associated with methemoglobin formation by 3,5-dichlorophenylhydroxylamine.	Nitrogen	118-119	hemoglobin subunit gamma 2	Homo sapiens	241-254
9088579-12	1997	CONCLUSIONS: In summary the theophylline 6 h plasma and 0-12 h urine ratios 1MU/13DMX and 3MX/13DMX, both reflecting N-demethylation seem to be predictors of the CYP1A2 mediated metabolism of theophylline, whereas only the plasma ratio correlated with the caffeine plasma 17DMX/13TMX ratio.	Nitrogen	2-3	thioredoxin related transmembrane protein 1	Homo sapiens	280-283
9084457-2	1997	At least three different P450s appear to be responsible for the N-demethylation of imipramine to desipramine in vivo: CYP1A2, CYP2C19, and CYP3A4.	Nitrogen	64-65	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	126-133
9099948-8	1997	M(r) approximately 94,000) M(r) fractions of mZP3 were purified and shown to vary in extent of asparagine-linked (N-linked) glycosylation.	Nitrogen	114-115	zona pellucida glycoprotein 3	Mus musculus	45-49
9070461-5	1997	The identification of the voltage-dependent whole-cell currents in vestibular dark cells was strengthened by the finding that a potent blocker of IsK channels, chromanol 293B, strongly reduced IIsK from 646 +/- 200 to 154 +/- 22 pA (71%) and gIsK from 7.5 +/- 2.6 to 2.8 +/- 0.4 nS (53%).	Nitrogen	279-281	potassium voltage-gated channel subfamily E regulatory subunit 1	Homo sapiens	146-149
9057853-4	1997	Three structural features seem to be essential for antitumor activities: a positive charge density at carbon C-7, a side chain at position C-2 or C-9 of the thiazoloquinoline skeleton with two basic nitrogens and a pKa value of 7.5-10 in the most basic center, and a conformational flexibility of this basic side chain.	Nitrogen	199-208	complement C9	Homo sapiens	146-149
9020168-4	1997	Targeted gene replacement shows that GCV3 is not required for growth on minimal medium; however, it is essential when glycine serves as the sole nitrogen source.	Nitrogen	145-153	glycine decarboxylase subunit H	Saccharomyces cerevisiae S288C	37-41
9023308-6	1997	The percentage contributions of CYP3A4 and CYP2C19 to the overall N-demethylation of CIT in human liver microsomes were estimated using a relative activity factor; respective values of 70% and 7% were calculated for microsomes obtained from livers from putative extensive metabolizers for (S)-mephenytoin 4"-hydroxylation.	Nitrogen	66-67	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	43-50
9137808-13	1997	NMH only inhibited G6PDH and GR activity, which is fully in accord with the proposed mechanism for N-substituted derivatives of HYAM.	Nitrogen	0-1	glucose-6-phosphate dehydrogenase	Homo sapiens	19-24
9137808-14	1997	However, NDMH a double N-substituted compound, caused a strikingly different scheme of reactivity inhibition of G6PDH but not of GR, severe methaemoglobin formation, only little lipid peroxidation and some impairment of NADPH methaemoglobin reductase.	Nitrogen	9-10	glucose-6-phosphate dehydrogenase	Homo sapiens	112-117
9058209-10	1997	Furthermore, all these changes seemed to correlate with the presence of fatty liver and the high serum free fatty acid levels, suggesting that disturbance of fatty acid metabolism affects nitrogen metabolism at least in part via altered gene expression of transcription factors such as HNF-4, C/EBP-alpha, and C/EBP-beta.	Nitrogen	188-196	hepatic nuclear factor 4, alpha	Mus musculus	286-291
8943261-10	1996	Glycosylation at N-333 and N-393 mainly contributed to the enzyme stability and prevented degradation at lysosomal acidic pH, whereas the low residual enzymatic activity of mutant ASM deficient in glycosylation at N-518 was caused by protein misfolding.	Nitrogen	17-18	sphingomyelin phosphodiesterase 1, acid lysosomal	Mus musculus	180-183
8960909-0	1996	An N-glycosylated tyrosinase epitope associates with newly synthesized MHC class I molecules in melanoma cells.	Nitrogen	3-4	tyrosinase	Homo sapiens	18-28
8960909-4	1996	One such antigenic epitope, corresponding to amino acids 369-377 of the enzyme tyrosinase, possesses an N-linked glycosylation site.	Nitrogen	104-105	tyrosinase	Homo sapiens	79-89
8952699-6	1996	The biochemical properties of this isoform are consistent with it being an N-linked glycosylated form of the AR precursor that contains unprocessed mannose residues.	Nitrogen	75-76	amphiregulin	Homo sapiens	109-111
8947526-1	1996	Alterations of the N-linked carbohydrate core structure of cell surface glycoproteins (beta 1-6 branching) can be detected by phytohemagglutinin (PHA-L) lectin binding and has been linked to tumor progression and K-ras activation in colon cancer.	Nitrogen	19-20	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	87-95
8947526-1	1996	Alterations of the N-linked carbohydrate core structure of cell surface glycoproteins (beta 1-6 branching) can be detected by phytohemagglutinin (PHA-L) lectin binding and has been linked to tumor progression and K-ras activation in colon cancer.	Nitrogen	19-20	KRAS proto-oncogene, GTPase	Homo sapiens	213-218
8902275-0	1996	N-oxygenation of primary amines and hydroxylamines and retroreduction of hydroxylamines by adult human liver microsomes and adult human flavin-containing monooxygenase 3.	Nitrogen	0-1	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	136-169
8806496-0	1996	Mutagenesis of the N-linked glycosylation sites of the yellow fever virus NS1 protein: effects on virus replication and mouse neurovirulence.	Nitrogen	19-20	influenza virus NS1A binding protein	Homo sapiens	74-77
8689924-11	1996	In the TPN + NS/NT versus TPN group, the ileal mucosa surrounding ulcers showed significantly greater crypt length (21%) and there was increased crypt-villus ratio (0.53 vs 0.39), crypt mitotic index (1.2 vs 0.9), and PCNA labeling (43% vs 30%).	Nitrogen	13-15	proliferating cell nuclear antigen	Rattus norvegicus	218-222
8647179-5	1996	The F4/80 molecule contains extensive N-linked glycosylation which contributes approximately 40 kDa to the mature molecule.	Nitrogen	38-39	adhesion G protein-coupled receptor E1	Mus musculus	4-9
8624781-8	1996	Fluorescent-linked immunoassays revealed that n-LDL increased ICAM-1 protein expression by twofold, which corresponded with increased ICAM-1 message levels.	Nitrogen	9-10	intercellular adhesion molecule 1	Homo sapiens	62-68
8735845-4	1996	In the series of N-protected tetrapeptides X30-Phg31-Asp32-Nal33-N(CH3)2, the Boc-substituent was shown to be optimal among the N-protecting groups Boc, 2Adoc, propionyl or acetyl when X = Trp.	Nitrogen	17-18	BOC cell adhesion associated, oncogene regulated	Rattus norvegicus	78-81
8846888-3	1996	PUT3 is a 979 amino acid protein that constitutively binds a short DNA sequence to the promoters of its target genes, but does not activate their expression in the absence of induction by proline and in the presence of preferred sources of nitrogen.	Nitrogen	240-248	Put3p	Saccharomyces cerevisiae S288C	0-4
17177827-4	1996	Compared with the phosphate-buffered saline solution-treated group, rats in the acidic fibroblast growth factor-treated group had significantly lower blood urea nitrogen (83.13 +/- 26.07 versus 176.36 +/- 62.36, p &lt; 0.05) and serum creatinine (0.73 +/- 0.14 versus 1.14 +/- 0.36, p &lt; 0.05) levels 1 day after occlusion.	Nitrogen	161-169	fibroblast growth factor 1	Rattus norvegicus	80-111
34893540-8	2021	Autophagic targeting of Cys/N-degron substrates is mediated by the autophagic N-recognin p62/SQTSM-1/Sequestosome-1 through recognition of K27/K63-linked ubiquitin (Ub) chains.	Nitrogen	28-29	sequestosome 1	Homo sapiens	89-92
34893540-8	2021	Autophagic targeting of Cys/N-degron substrates is mediated by the autophagic N-recognin p62/SQTSM-1/Sequestosome-1 through recognition of K27/K63-linked ubiquitin (Ub) chains.	Nitrogen	28-29	sequestosome 1	Homo sapiens	101-115
34966404-8	2021	An increase was observed in some key enzymatic activities and transcription involved in nitrogen metabolism, such as that of nitrate reductase, nitrite reductase, glutamate synthase, and glutamine synthetase, in melatonin-treated, drought-stressed maize.	Nitrogen	88-96	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	163-181
34303244-8	2021	It is speculated that denitrifying bacteria harboring ARGs played crucial roles in protecting nitrogen transformation from low-level antibiotics stress in the reservoir.	Nitrogen	94-102	serpin family A member 2 (gene/pseudogene)	Homo sapiens	54-58
34303244-9	2021	Our results highlight that denitrifying bacteria are important hosts of ARGs, which provides a novel perspective for evaluating the effects of antibiotics on nitrogen cycle in natural aquatic ecosystems.	Nitrogen	158-166	serpin family A member 2 (gene/pseudogene)	Homo sapiens	72-76
34940412-4	2021	The results of the MBR-MBfR experiments indicated that a C/N ratio of two was suitable for NH4+-N, NO2--N, NO3--N, and chemical oxygen demand (COD) removal in partial nitrification-denitrification (PN-D) and hydrogen autotrophic denitrification for further treatment.	Nitrogen	59-60	translocator protein	Homo sapiens	19-22
8601595-2	1996	In the present work we examine the role of N-linked glycosylation and Ser-Gly motifs in regulating CD44-hyaluronate interaction.	Nitrogen	43-44	CD44 molecule (Indian blood group)	Homo sapiens	99-103
8601595-3	1996	Our results show that treatment of a panel of human cell lines which constitutively express CD44 with the inhibitor of N-linked glycosylation tunicamycin results in the loss of attachment of these cells to hyaluronate-coated substrate.	Nitrogen	119-120	CD44 molecule (Indian blood group)	Homo sapiens	92-96
8601595-5	1996	Using human melanoma cells stably transfected with CD44 N-linked glycosylation site-specific mutants, we show that integrity of five potential N-linked glycosylation sites within the hyaluronate recognition domain of CD44 is critical for hyaluronate binding.	Nitrogen	56-57	CD44 molecule (Indian blood group)	Homo sapiens	51-55
8601595-5	1996	Using human melanoma cells stably transfected with CD44 N-linked glycosylation site-specific mutants, we show that integrity of five potential N-linked glycosylation sites within the hyaluronate recognition domain of CD44 is critical for hyaluronate binding.	Nitrogen	56-57	CD44 molecule (Indian blood group)	Homo sapiens	217-221
8601595-5	1996	Using human melanoma cells stably transfected with CD44 N-linked glycosylation site-specific mutants, we show that integrity of five potential N-linked glycosylation sites within the hyaluronate recognition domain of CD44 is critical for hyaluronate binding.	Nitrogen	143-144	CD44 molecule (Indian blood group)	Homo sapiens	51-55
8601595-5	1996	Using human melanoma cells stably transfected with CD44 N-linked glycosylation site-specific mutants, we show that integrity of five potential N-linked glycosylation sites within the hyaluronate recognition domain of CD44 is critical for hyaluronate binding.	Nitrogen	143-144	CD44 molecule (Indian blood group)	Homo sapiens	217-221
8601595-6	1996	Mutation of any one of these potential N-linked glycosylation sites abrogates CD44-mediated melanoma cell attachment to hyaluronate-coated surfaces, suggesting that all five sites are necessary to maintain the HA-recognition domain in the appropriate conformation.	Nitrogen	39-40	CD44 molecule (Indian blood group)	Homo sapiens	78-82
8622686-4	1996	The demonstration that NCR-sensitive expression of multiple nitrogen-catabolic genes occurs in a gln3 delta ure2 delta dal80::hisG triple mutant indicated that the prevailing view of the nitrogen regulatory circuit was in need of revision; additional components clearly existed.	Nitrogen	60-68	Dal80p	Saccharomyces cerevisiae S288C	119-124
8639667-1	1996	Sialylated oligosaccharide structures were determined by the technique of electrospray ionization mass spectroscopy at seven of eight N-linked glycosylation sites of recombinant human ICAM-1des454-532 [tICAM(453)] purified from the tissue culture fluid of Chinese hamster ovary, human embryonic kidney, and mouse myeloma cell lines.	Nitrogen	134-135	intercellular adhesion molecule 1	Homo sapiens	184-190
34553505-3	2021	Based on the structure-activity relationship and in vitro 2D NMR studies employing 15 N-labeled IL-33, we identified that the oxazolo(4,5- c )-quinolinone analog 7c binds to the interface region of IL-33 and IL-33 receptor (ST2), an orphan receptor of the IL-1 receptor family.	Nitrogen	86-87	ST2	Homo sapiens	224-227
34762772-2	2022	Pdx2 employs a Cys-His-Glu catalytic triad to deaminate glutamine to glutamate and ammonia-the source of the nitrogen of pyridoxal 5"-phosphate(PLP).	Nitrogen	109-117	proteolipid protein 1	Homo sapiens	144-147
34771350-3	2021	Thermal degradation behavior under N2 gas indicates that the higher LnK content, the better thermal stability of the composites (over 30  C of Td10% for ELO + 15% LnK), while for the experiment under air-oxidant atmosphere, the lower LnK content (5%) conducted to the more thermo-stable material.	Nitrogen	35-37	SH2B adaptor protein 3	Homo sapiens	68-71
16275904-1	2005	In cells of Saccharomyces cerevisiae, using ammonia as a source of nitrogen, Gln3p is sequestered in the cytoplasm by Ure2p but enters the nucleus when the cells are shifted to a nonpreferred source of nitrogen such as proline.	Nitrogen	202-210	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	77-82
34827108-4	2021	Serum biochemical examinations revealed that both the creatinine and blood urea nitrogen concentrations were significantly higher in the Vit D3-treated group.	Nitrogen	80-88	vitrin	Mus musculus	137-140
8838441-10	1996	Three metabolites were detected in plasma and urine, one of which, the N-desmethyl metabolite, has 5-HT1D agonist activity.	Nitrogen	71-72	5-hydroxytryptamine receptor 1D	Homo sapiens	99-105
16275904-3	2005	As a consequence of the drop in glutamine concentration, Gln3p is able to enter the nucleus and to activate the transcription of nitrogen-regulated genes.	Nitrogen	129-137	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	57-62
8580967-10	1996	The intracellular nitrogen to carbon ratio might be an important factor for the regulation of asparagine synthetase gene expression.	Nitrogen	18-26	LOC100856906	Zea mays	94-115
34677535-0	2021	A Study to Enhance the Nitrate-Nitrogen Removal Rate without Dismantling the NF Module by Building a PFSA Ionomer-Coated NF Module.	Nitrogen	31-39	neurofascin	Homo sapiens	121-123
15944213-5	2005	In humans, CYP1A2 catalyzed N-hydroxylation and subsequent UGT1A-mediated glucuronidation is a dominant pathway in the metabolism of PhIP.	Nitrogen	28-29	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	11-17
34274480-12	2021	The amino terminal ends of both the CBLN1 and CBLN3 proteins contain three possible N-linked glycosylation sites.	Nitrogen	84-85	cerebellin 1 precursor	Homo sapiens	36-41
34939013-3	2021	Our objective was to investigate the potential effects of marine n-3 PUFA supplementation on the SASP secretome in kidney transplant recipients.	Nitrogen	65-66	pumilio RNA binding family member 3	Homo sapiens	69-73
11012204-6	1996	Glycopeptidase F digestion and amino sugar analysis of the factor demonstrated that MPF is a glycoprotein carrying at least one N-linked sugar chain.	Nitrogen	128-129	mesothelin	Homo sapiens	84-87
16021504-2	2005	Recently, we proved that tobacco CND41 protease is involved in Rubisco degradation and the translocation of nitrogen during senescence.	Nitrogen	108-116	aspartyl protease family protein At5g10770-like	Nicotiana tabacum	33-38
7548083-7	1995	The experiments showed for MLT tetramer in aqueous phosphate buffer that the amino nitrogen of Gly-1 has a pKa of 8.15, and that the Lys-7, Lys-21, and Lys-23 side chain nitrogen atoms have pKa values of 10.21, 10.03, and 10.24 respectively.	Nitrogen	83-91	melittin	Apis mellifera	27-30
34473424-4	2021	Theoretical modeling suggests that the NRR preferably takes place on FeN4 instead of MoN4 , and the transition of Fe spin state significantly lowers the energy barrier of the potential determining step, which is conducive to the first hydrogenation of N2 .	Nitrogen	252-254	spindlin 1	Homo sapiens	117-121
8557170-2	1995	The human and rat CRF-BP cDNAs encode proteins of 322 amino acids with one putative signal sequence, one N-glycosylation site, and 10 conserved cysteines.	Nitrogen	27-28	corticotropin releasing hormone binding protein	Rattus norvegicus	18-24
16021504-6	2005	Further studies of seedlings under senescence induced by combined treatment with nitrogen-starvation and high sucrose confirmed that the processing of CND41 was important for protease activity and senescence.	Nitrogen	81-89	aspartyl protease family protein At5g10770-like	Nicotiana tabacum	151-156
16388471-4	2005	In this study, a set of experiments was performed to elucidate the effect of N nutrition on the activities of key enzymes involved in flavonoid biosynthesis (phenylalanine ammonia-lyase [PAL], chalcone synthase/chalcone isomerase [CHS/CHI}, flavanone 3-hydroxylase [FHT], flavonol synthase [FLS], dihydroflavonol 4-reductase [DFR]) and the accumulation of different groups of phenylpropanoids.	Nitrogen	77-78	flavonol synthase/flavanone 3-hydroxylase	Malus domestica	272-289
8709854-7	1995	fdxH2 and the nif2 genes of Anabaena 29413 are also transcribed &lt; or = 4 h after onset of nitrogen-stepdown, exclusively under anaerobic growth conditions and long before functional heterocysts appear.	Nitrogen	93-101	zinc finger protein 335	Homo sapiens	14-18
8709854-15	1995	To simultaneously allow for oxygen-evolving photosynthesis and oxygen-sensitive nitrogen fixation, the Nif1-type system probably branched from an ancestral Nif2-type system and has evolved for an exclusive operation within heterocysts.	Nitrogen	80-88	zinc finger protein 335	Homo sapiens	103-107
8709854-15	1995	To simultaneously allow for oxygen-evolving photosynthesis and oxygen-sensitive nitrogen fixation, the Nif1-type system probably branched from an ancestral Nif2-type system and has evolved for an exclusive operation within heterocysts.	Nitrogen	80-88	zinc finger protein 335	Homo sapiens	156-160
7627960-1	1995	Human polymorphic N-acetyltransferase (NAT2) catalyzes the N-acetylation of arylamine carcinogens and the metabolic activation of N-hydroxyarylamine and N-hydroxyarylamide carcinogens by O- and N,O-acetylation, respectively.	Nitrogen	18-19	N-acetyltransferase 2	Homo sapiens	39-43
7632941-6	1995	PETA-3 has a single consensus sequence for N-linked glycosylation located in this extracellular loop.	Nitrogen	43-44	CD151 molecule (Raph blood group)	Homo sapiens	0-6
34533312-1	2021	An atom-economic N-to-C-directed solid-phase peptide synthesis is reported that uses benzyl (Bn) or (benzhydryl-carbamoyl)-methyl (BcM) esters of amino acids as the building blocks, which facilitate efficient hydrazinolysis, convenient conversion to acyl azide, and robust amidation with the next amino acid ester.	Nitrogen	17-19	TNF receptor superfamily member 17	Homo sapiens	131-134
34638666-1	2021	Once weak ultraviolet ray-B (UVB) irradiates the skin cells, the generation of reactive nitrogen species (RNS), but not reactive oxygen species (ROS), is stimulated for the mislocalization of claudin-1 (CLDN1), an essential protein for forming tight junctions (TJs).	Nitrogen	88-96	claudin 1	Homo sapiens	192-201
34638666-1	2021	Once weak ultraviolet ray-B (UVB) irradiates the skin cells, the generation of reactive nitrogen species (RNS), but not reactive oxygen species (ROS), is stimulated for the mislocalization of claudin-1 (CLDN1), an essential protein for forming tight junctions (TJs).	Nitrogen	88-96	claudin 1	Homo sapiens	203-208
34502264-6	2021	We designed a complex with non-cytotoxic LMWP to prevent the degradation of Oct4 and revealed that the positively charged cell-permeable LMWP helped condense the size of the Oct4-LMWP complexes (1:5 N:P ratio).	Nitrogen	199-200	POU domain, class 5, transcription factor 1	Mus musculus	76-80
34502264-6	2021	We designed a complex with non-cytotoxic LMWP to prevent the degradation of Oct4 and revealed that the positively charged cell-permeable LMWP helped condense the size of the Oct4-LMWP complexes (1:5 N:P ratio).	Nitrogen	199-200	POU domain, class 5, transcription factor 1	Mus musculus	174-178
34443418-3	2021	In an attempt to optimize the electrode structure, we report on a self-assembly synthesis of silicon nanoparticles@nitrogen-doped reduced graphene oxide/carbon nanofiber (Si@N-doped rGO/CNF) composites as potential high-performance anodes for LIB through electrostatic attraction.	Nitrogen	115-123	NPHS1 adhesion molecule, nephrin	Homo sapiens	186-189
7543138-8	1995	Variant and parental cell-derived CD44 molecules exhibited differences in migration on sodium dodecyl sulfate-polyacrylamide gel electrophoresis that were partly attributable to differences in N-linked glycosylation.	Nitrogen	193-194	CD44 antigen	Mus musculus	34-38
16388471-4	2005	In this study, a set of experiments was performed to elucidate the effect of N nutrition on the activities of key enzymes involved in flavonoid biosynthesis (phenylalanine ammonia-lyase [PAL], chalcone synthase/chalcone isomerase [CHS/CHI}, flavanone 3-hydroxylase [FHT], flavonol synthase [FLS], dihydroflavonol 4-reductase [DFR]) and the accumulation of different groups of phenylpropanoids.	Nitrogen	77-78	flavonol synthase/flavanone 3-hydroxylase	Malus domestica	291-294
34140212-1	2021	PMM2-CDG is the most common congenital disorder of glycosylation (CDG) accounting for almost 65% of known CDG cases affecting N-glycosylation.	Nitrogen	126-127	phosphomannomutase 2	Homo sapiens	0-4
16318282-6	2005	Moreover,ectopic expression of OsSTY kinase gene in yeast Saccharomyces cerevisiae ste7/ste7 mutant partially suppressed the pseudohyphal development defect of the strain under the condition of nitrogen starvation.	Nitrogen	194-202	mitogen-activated protein kinase kinase STE7	Saccharomyces cerevisiae S288C	83-87
34368525-5	2021	In contrast, the enlarged Co-N bond length of the latter dative contact in the H-non-dissociated case not only destroys the spinterface coupling but also blocks the spin injection.	Nitrogen	29-30	spindlin 1	Homo sapiens	165-169
8519911-5	1995	In the remaining 26 dogs having detectable plasma EPO, the plasma concentration rate of EPO related to blood urea nitrogen and serum creatinine values.	Nitrogen	114-122	erythropoietin	Canis lupus familiaris	88-91
16318282-6	2005	Moreover,ectopic expression of OsSTY kinase gene in yeast Saccharomyces cerevisiae ste7/ste7 mutant partially suppressed the pseudohyphal development defect of the strain under the condition of nitrogen starvation.	Nitrogen	194-202	mitogen-activated protein kinase kinase STE7	Saccharomyces cerevisiae S288C	88-92
8530029-5	1995	Like NPI, NPII has potential N-linked glycosylation sites.	Nitrogen	5-6	neuronal pentraxin 2	Homo sapiens	10-14
16332000-4	2005	This is expected because the EMI+ involves an ethyl group bound to the N atom of the imidazolium ring, and the ethyl group can rotate along the C-N bond to yield conformers.	Nitrogen	71-72	elastin microfibril interfacer 1	Homo sapiens	29-32
7896706-11	1995	Several putative Gcn4p binding sequences are present in the PDX3 promoter region, leading to the assumption that transcription of this gene is under the general control of nitrogen metabolism.	Nitrogen	172-180	pyridoxamine-phosphate oxidase PDX3	Saccharomyces cerevisiae S288C	60-64
34276718-9	2021	We further confirmed that two N-glycosylation clients, peroxidases PRX32 and PRX34, were involved in the salt stress response since the double mutants showed enhanced salt sensitivity.	Nitrogen	30-31	peroxidase CB	Arabidopsis thaliana	77-82
34270279-2	2021	The single electron spin of a near-surface nitrogen-vacancy center in diamond is used as the quantum sensor, and a fused-silica half-sphere lens is taken as the source of the moving nucleons.	Nitrogen	43-51	spindlin 1	Homo sapiens	20-24
16332000-4	2005	This is expected because the EMI+ involves an ethyl group bound to the N atom of the imidazolium ring, and the ethyl group can rotate along the C-N bond to yield conformers.	Nitrogen	146-147	elastin microfibril interfacer 1	Homo sapiens	29-32
15865159-2	2005	The initial steps of the catabolism were investigated in cell-free extracts of the bacterial strain MM 1 able to grow with methyl-triethanol-ammonium as sole source of carbon, energy and nitrogen.	Nitrogen	187-195	plexin B2	Homo sapiens	100-104
34085593-5	2021	Conversely, absence of a nitrogen source suppresses TORC1 in a manner dependent on GATOR1 as well as the Tsc1-Tsc2 complex, whose mammalian equivalent functions as a growth-factor sensitive TORC1 inhibitor.	Nitrogen	25-33	TSC complex subunit 2	Homo sapiens	110-114
16834223-8	2005	Proton affinity (PA) of histidine calculated by the G3(MP2) method is 233.2 and 232.4 kcal mol(-1) for protonation at the imidazole ring and at the amino group nitrogens, respectively, which is about 3-5 kcal mol(-1) lower than the reported experimental value.	Nitrogen	160-169	tryptase pseudogene 1	Homo sapiens	55-58
34447955-8	2021	The total tract digestibility of dry matter and nitrogen was linearly increased with the graded level of GOx supplement.	Nitrogen	48-56	hydroxyacid oxidase 1	Homo sapiens	105-108
16167840-9	2005	PhIP was preferentially metabolized by N2-hydroxylation in hCYP1A2 mice, whereas in wild-type mice, 4"-hydroxylation was the predominant pathway.	Nitrogen	39-41	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	59-66
34276694-6	2021	We demonstrated that MMP-9 efficiently cleaved human IL-7 in the exposed loop between the alpha-helices C and D and that this process is delayed by IL-7 N-linked glycosylation.	Nitrogen	153-154	matrix metallopeptidase 9	Homo sapiens	21-26
34085828-2	2021	Stoichiometric TaO2(H2O)n+ cations are generated by the laser vaporization of a tantalum metal target in the pulsed supersonic expansion of H2O/He mixed gas.	Nitrogen	24-26	TAO kinase 2	Homo sapiens	15-19
34116636-10	2021	The co-expression of gdh3 and gdh2 in the fine roots increased nitrogen agronomic efficiency.	Nitrogen	63-71	glutamate dehydrogenase 2	Homo sapiens	30-34
16085187-7	2005	We next found, however, that nitrogen mustards (chlorambucil and melphalan) and alkyl sulfonates (busulfan) efficiently inhibited TrxR while these compounds, surprisingly, did not inhibit GR.	Nitrogen	29-37	peroxiredoxin 5	Homo sapiens	130-134
34206001-0	2021	Spin-Mechanics with Nitrogen-Vacancy Centers and Trapped Particles.	Nitrogen	20-28	spindlin 1	Homo sapiens	0-4
34206001-4	2021	To enter the quantum regime, schemes using single long-lived atomic spins, such as the electronic spin of nitrogen-vacancy (NV) centers in diamond, coupled with levitating mechanical oscillators have been proposed.	Nitrogen	106-114	spindlin 1	Homo sapiens	98-102
16076117-10	2005	Fluorescence two-dimensional difference gel electrophoresis of soybean seed proteins revealed that nitrogen application favored the accumulation of the beta-subunit of beta-conglycinin while decreasing the accumulation of Bowman-Birk protease inhibitor (BBI), a protein rich in cysteine.	Nitrogen	99-107	beta-conglycinin beta subunit 1	Glycine max	152-184
16076117-10	2005	Fluorescence two-dimensional difference gel electrophoresis of soybean seed proteins revealed that nitrogen application favored the accumulation of the beta-subunit of beta-conglycinin while decreasing the accumulation of Bowman-Birk protease inhibitor (BBI), a protein rich in cysteine.	Nitrogen	99-107	LOC547785	Glycine max	222-252
16076117-10	2005	Fluorescence two-dimensional difference gel electrophoresis of soybean seed proteins revealed that nitrogen application favored the accumulation of the beta-subunit of beta-conglycinin while decreasing the accumulation of Bowman-Birk protease inhibitor (BBI), a protein rich in cysteine.	Nitrogen	99-107	LOC547785	Glycine max	254-257
16076117-12	2005	Northern blot analysis indicated that nitrogen had a negative influence on the expression of the BBI gene.	Nitrogen	38-46	LOC547785	Glycine max	97-100
35483187-6	2022	IDs were further identified to display anti-pseudo-allergic activity by binding MRGPRX2 with the tertiary nitrogen substructures, just liking the reported MRGPRX2-ligand.	Nitrogen	106-114	MAS-related GPR, member X2	Mus musculus	80-87
16002696-9	2005	Removal of the N-linked glycosylation site from the FcRn H chain resulted in a decreased association of the FcRn H chain for beta(2)m.	Nitrogen	15-16	beta-2-microglobulin	Homo sapiens	125-133
35358383-5	2022	In contrast to all-carbon nanobelts, NB1 and NB2 contain multiple pyrrolic nitrogen donors that could serve as potential metal coordination sites.	Nitrogen	75-83	contactin 5	Homo sapiens	45-48
35602867-8	2022	In conclusion, combining 15% fly ash with 0.5 g nitrogen in the form of urea significantly enhanced radish yield by enhancing antioxidant activity such as catalase, peroxidase, ascorbate peroxidase, Guaiacol peroxidase, superoxide dismutase, nitrate reductase and reducing oxidative stress, potentially reducing fly ash accumulation and environmental pollution.	Nitrogen	48-56	peroxidase E5-like	Raphanus sativus	165-175
16002699-6	2005	C122-independent dimerization of CTLA-4 involved N-glycosylation, because further mutation of the N78 and N110 glycosylation sites abrogated dimerization.	Nitrogen	49-50	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	33-39
15788482-10	2005	After the ezrin oligomers were separated from monomers, FRET was observed in both forms, indicating intramolecular and intermolecular N-C binding.	Nitrogen	134-135	ezrin	Homo sapiens	10-15
15925307-3	2005	In this way we have identified two genes, NGR1 and GID7, whose disruption leads to an enhanced catabolism of sugar in an industrial strain and/or a laboratory strain, during growth in a chemically defined grape juice medium with limiting nitrogen.	Nitrogen	238-246	glucose-induced degradation complex subunit GID7	Saccharomyces cerevisiae S288C	51-55
35625866-7	2022	Treatment with BMNO containing high (vs. low) n-6:n-3 PUFA ratios significantly increased the mRNA expression of lipogenic genes (acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase); however, there was no effect when cells were treated with BMO (with either low or high n-6:n-3 PUFA ratios).	Nitrogen	46-47	fatty acid synthase	Homo sapiens	154-173
35625866-7	2022	Treatment with BMNO containing high (vs. low) n-6:n-3 PUFA ratios significantly increased the mRNA expression of lipogenic genes (acetyl-CoA carboxylase, fatty acid synthase, and stearoyl-CoA desaturase); however, there was no effect when cells were treated with BMO (with either low or high n-6:n-3 PUFA ratios).	Nitrogen	46-47	stearoyl-CoA desaturase	Homo sapiens	179-202
15907104-2	2005	A simple, useful reaction between Ru2(OAc)4Cl (OAc- = acetate) and catechol derivatives in the presence of bases afforded a variety of diruthenium complexes, generally formulated as [Na(n){Ru2(R4Cat)4}] (n = 2 or 3; R4 = -F4, -Cl4, -Br4, -H4, -3,5-di-t-Bu, and -3,6-di-t-Bu; Cat(2-) = catecholate).	Nitrogen	186-188	doublecortin domain containing 2	Homo sapiens	34-45
35620110-4	2022	Functional analysis showed that among the CRs identified, Ahc1p and Eaf3p promoted the utilization of non-preferred nitrogen sources through global regulation of nitrogen metabolism.	Nitrogen	162-170	Eaf3p	Saccharomyces cerevisiae S288C	68-73
35620110-5	2022	Ahc1p regulated nitrogen metabolism through amino acid transport, nitrogen catabolism repression (NCR), and the Ssy1p-Ptr3p-Ssy5p signaling sensor system.	Nitrogen	16-24	Ahc1p	Saccharomyces cerevisiae S288C	0-5
35620110-5	2022	Ahc1p regulated nitrogen metabolism through amino acid transport, nitrogen catabolism repression (NCR), and the Ssy1p-Ptr3p-Ssy5p signaling sensor system.	Nitrogen	16-24	Ssy5p	Saccharomyces cerevisiae S288C	124-129
35620110-5	2022	Ahc1p regulated nitrogen metabolism through amino acid transport, nitrogen catabolism repression (NCR), and the Ssy1p-Ptr3p-Ssy5p signaling sensor system.	Nitrogen	66-74	Ahc1p	Saccharomyces cerevisiae S288C	0-5
35620110-6	2022	Eaf3p regulated nitrogen metabolism via amino acid transport and NCR.	Nitrogen	16-24	Eaf3p	Saccharomyces cerevisiae S288C	0-5
15780659-2	2005	One such system, the target of rapamycin (Tor) proteins, senses nutrients and uses the GATA activators Gln3p and Nil1p to regulate translation in response to low-quality carbon and nitrogen.	Nitrogen	181-189	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	103-108
35620110-7	2022	The regulatory mechanisms of the effects of Ahc1p and Eaf3p on nitrogen metabolism depended on the function of their histone acetyltransferase complex ADA and NuA4.	Nitrogen	63-71	Ahc1p	Saccharomyces cerevisiae S288C	44-49
35620110-7	2022	The regulatory mechanisms of the effects of Ahc1p and Eaf3p on nitrogen metabolism depended on the function of their histone acetyltransferase complex ADA and NuA4.	Nitrogen	63-71	Eaf3p	Saccharomyces cerevisiae S288C	54-59
15780659-4	2005	When carbon and nitrogen are abundant, the phosphorylated Ure2p anchors the also phosphorylated Gln3p and Nil1p in the cytoplasm.	Nitrogen	16-24	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	96-101
15780659-5	2005	Upon a shift from high- to low-quality nitrogen or treatment with rapamycin all three proteins are dephosphorylated, causing Gln3p and Nil1p to enter the nucleus and promote transcription.	Nitrogen	39-47	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	125-130
35565936-4	2022	In this context, it is necessary to find new and sustainable sources of n-3 LC-PUFA.	Nitrogen	72-73	pumilio RNA binding family member 3	Homo sapiens	79-83
15499570-1	2005	Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2.	Nitrogen	204-205	mucin 4, cell surface associated	Rattus norvegicus	0-4
35405066-1	2022	Emissions of NH3 and nine nitrogen-containing volatile organic compounds (NVOCs) (C1-3-amines, C1-3-amides, and C1-3-imines) from motor vehicles powered by gasoline, diesel, and natural gas under low-speed driving conditions from roadside in situ measurements were characterized using a water-cluster chemical ionization mass spectrometer and trace gas monitors.	Nitrogen	26-34	homeobox C13	Homo sapiens	82-86
35546194-4	2022	We apply this method to realize pressures of about 600 and 900 gigapascals in a laser-heated double-stage diamond anvil cell3, producing a rhenium-nitrogen alloy and achieving the synthesis of rhenium nitride Re7N3-which, as our theoretical analysis shows, is only stable under extreme compression.	Nitrogen	147-155	carboxyl ester lipase pseudogene	Homo sapiens	120-125
15499570-1	2005	Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2.	Nitrogen	204-205	mucin 4, cell surface associated	Rattus norvegicus	128-134
15499570-1	2005	Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2.	Nitrogen	204-205	mucin 4, cell surface associated	Rattus norvegicus	136-163
15632147-5	2005	When expressed in Xenopus oocytes, rat SIT1 mediated the uptake of imino acids such as proline (K0.5 approximately 0.2 mM) and pipecolate, as well as N-methylated amino acids (e.g. MeAIB, sarcosine).	Nitrogen	150-151	solute carrier family 6 member 20	Homo sapiens	39-43
35380292-9	2022	RESULTS: Serum creatinine, urea nitrogen and glucose, and PPARgamma and GLUT1 expression in rat PF model were reduced by PPARgamma agonists Rosiglitazone or 15d-PGJ2 and elevated by antagonist GW9662.	Nitrogen	32-40	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	121-130
35151689-10	2022	Furthermore, the expression of transcription factor SOX4 was upregulated upon TGF-beta stimulation, and its depletion blocked TGF-beta-induced N-glycomic changes.	Nitrogen	143-144	SRY-box transcription factor 4	Homo sapiens	52-56
35151689-11	2022	Thus, TGF-beta-induced N-glycosylation changes can occur in a SOX4-dependent and SMAD4-independent manner in the pancreatic PaTu-S cancer cell line.	Nitrogen	23-24	SRY-box transcription factor 4	Homo sapiens	62-66
19791368-1	2005	Complexes of fluorinated benzenes (o-C6H4-nF2+n) and Mg*+ are subjected to ultraviolet photodissociation (260-340 nm), producing efficiently benzyne radical cations (C6H4-nFn*+) besides Mg*+ and MgF+.	Nitrogen	19-20	signal transducer and activator of transcription 5A	Homo sapiens	195-198
35198253-8	2022	MAGT1 also acts as an accessory protein for STT3B, as catalytic subunits of the oligosaccharyltransferase protein complex, which carries out glycan chain transfer to proteins in the endoplasmic reticulum during N-glycosylation.	Nitrogen	211-212	magnesium transporter 1	Homo sapiens	0-5
34981577-4	2022	In this study, via examination by lectin blotting, HPLC, and mass spectrometry analysis, however, we found that the amounts of GlcNAc-branched tri-antennary N-glycans catalyzed by N-acetylglucosaminyltransferase IV (GnT-IV) and tetra-antennary N-glycans were significantly decreased in O-GlcNAc transferase knockdown cells (OGT-KD) compared with those in wild type cells.	Nitrogen	180-182	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	216-222
15661661-8	2005	This result suggests that the free 8-oxoG base may retain in the recognition site following N-glycosylic cleavage, implying that product inhibition contribute to uncoupling the activities of hOgg1.	Nitrogen	92-93	8-oxoguanine DNA glycosylase	Homo sapiens	191-196
35159460-5	2022	The amino nitrogen atom and carboxyl oxygen atom of the functional groups on the surface of the FNs were the main binding sites for the chelation of Ca(II).	Nitrogen	10-18	carbonic anhydrase 2	Homo sapiens	149-155
15723445-6	2005	Administration of an adenovirus encoding CT-1 to NS-398-treated rats restituted normal levels of COX-1, prostaglandins, and VEGF in the liver after partial hepatectomy and restored normal liver regeneration.	Nitrogen	49-51	vascular endothelial growth factor A	Rattus norvegicus	124-128
35425220-3	2022	The Fe/Co/porous carbon nanoparticles were uniformly dispersed on graphene with high specific surface area and large porosity, which endow high nitrogen doping and many more active sites with better ORR performance than the commercial 20 wt% Pt/C.	Nitrogen	144-152	general transcription factor IIE subunit 1	Homo sapiens	4-6
32287548-3	2005	Furthermore, we identified three pairs of non-canonical N-H pi interactions in the structure of ORF3, which can make contributions to the stability of protein structure.	Nitrogen	56-57	ankyrin repeat, SAM and basic leucine zipper domain containing 1	Homo sapiens	96-100
35011724-0	2022	N-Glycosylation Facilitates 4-1BB Membrane Localization by Avoiding Its Multimerization.	Nitrogen	0-1	TNF receptor superfamily member 9	Homo sapiens	28-33
35011724-4	2022	It has been previously demonstrated that 4-1BB is heavily modified by N-glycosylation; however, the biological importance of this modification lacks detailed elucidation.	Nitrogen	70-71	TNF receptor superfamily member 9	Homo sapiens	41-46
35011724-5	2022	Through biochemical, biophysical, and cell-biological approaches, we systematically evaluated the impact of N-glycosylation on the ligand interaction, stability, and localization of 4-1BB.	Nitrogen	108-109	TNF receptor superfamily member 9	Homo sapiens	182-187
35011724-8	2022	The N-glycosylation-guided intracellular processing of 4-1BB serves as the potential mechanism explicitly modulating the "on" and "off" of 4-1BB through the control of protein abundance.	Nitrogen	4-5	TNF receptor superfamily member 9	Homo sapiens	55-60
35011724-8	2022	The N-glycosylation-guided intracellular processing of 4-1BB serves as the potential mechanism explicitly modulating the "on" and "off" of 4-1BB through the control of protein abundance.	Nitrogen	4-5	TNF receptor superfamily member 9	Homo sapiens	139-144
15572362-6	2005	Genomic analyses of Tyrc-em mice showed a C1220T nucleotide substitution within the Tyr encoding region, resulting in a T373I amino acid change, which abolishes an N-glycosylation sequon located in the second metal ion binding site of the enzyme.	Nitrogen	164-165	tyrosinase	Mus musculus	20-23
35049904-8	2022	While the two quaternary nitrogen analogs, relative to their respective tertiary amines, displayed lower alpha4beta2 nAChR binding affinities, both displayed much higher affinities for the Torpedo muscle nAChR and rat alpha7 brain receptors than their respective tertiary amine forms.	Nitrogen	25-33	cholinergic receptor nicotinic beta 1 subunit	Rattus norvegicus	117-122
7753050-5	1995	Feline CD9 is unique in that it lacks a potential N-linked glycosylation site in the first extracellular loop, a feature common to CD9 of other species.	Nitrogen	50-51	CD9 molecule	Homo sapiens	7-10
7891726-8	1995	Although PUT3, the proline utilization pathway transcriptional activator, is absolutely required for growth on proline as the sole nitrogen source, a put3 ure2 strain had somewhat elevated PUT gene expression, suggesting an effect of the ure2 mutation in the absence of the PUT3 product.	Nitrogen	131-139	Put3p	Saccharomyces cerevisiae S288C	9-13
7890742-5	1995	The results showed that the single CD52 N-glycosylation site is occupied by large sialylated, polylactosamine-containing, core-fucosylated tetraantennary oligosaccharides.	Nitrogen	40-41	CD52 molecule	Homo sapiens	35-39
7795387-0	1995	N-glycosylation site mapping of recombinant tissue plasminogen activator by micellar electrokinetic capillary chromatography.	Nitrogen	0-1	chromosome 20 open reading frame 181	Homo sapiens	44-72
7795387-1	1995	This report describes the N-glycosylation mapping of recombinant tissue plasminogen activator (rt-PA) using micellar electrokinetic capillary chromatography.	Nitrogen	26-27	chromosome 20 open reading frame 181	Homo sapiens	65-93
7899075-1	1995	The S. cerevisiae Uga43(Dal80) protein down-regulates the expression of multiple nitrogen pathway genes.	Nitrogen	81-89	Dal80p	Saccharomyces cerevisiae S288C	18-23
7899075-6	1995	One system is Uga43p-dependent; it operates in cells grown on a poor nitrogen source.	Nitrogen	69-77	Dal80p	Saccharomyces cerevisiae S288C	14-20
7899075-8	1995	Nitrogen repression also blocks the synthesis of Uga43p, making the two repression systems mutually exclusive.	Nitrogen	0-8	Dal80p	Saccharomyces cerevisiae S288C	49-55
7776966-0	1995	Identification of the sites of N-linked glycosylation on the follicle-stimulating hormone (FSH) receptor and assessment of their role in FSH receptor function.	Nitrogen	31-32	follicle stimulating hormone receptor	Homo sapiens	61-104
7776966-1	1995	The FSH receptor (FSHR) contains a large extracellular domain in which exist three potential sites for N-linked glycosylation.	Nitrogen	103-104	follicle stimulating hormone receptor	Homo sapiens	4-16
7776966-1	1995	The FSH receptor (FSHR) contains a large extracellular domain in which exist three potential sites for N-linked glycosylation.	Nitrogen	103-104	follicle stimulating hormone receptor	Homo sapiens	18-22
7776966-6	1995	The above results suggest that N-linked FSHR carbohydrates may, in some way, be required for FSH binding.	Nitrogen	31-32	follicle stimulating hormone receptor	Homo sapiens	40-44
7776966-10	1995	Binding assays demonstrate that these two N-linked FSHR carbohydrates are redundant in function since carbohydrate at either Asn174 or Asn276 allows the receptor to be expressed on the cell surface and to bind FSH with normal affinity.	Nitrogen	42-43	follicle stimulating hormone receptor	Homo sapiens	51-55
7776966-12	1995	Similarly, when cells expressing the wild type FSHR were treated with tunicamycin to prevent N-linked glycosylation, the resulting nonglycosylated FSHR was not able to bind FSH.	Nitrogen	93-94	follicle stimulating hormone receptor	Homo sapiens	47-51
7776966-12	1995	Similarly, when cells expressing the wild type FSHR were treated with tunicamycin to prevent N-linked glycosylation, the resulting nonglycosylated FSHR was not able to bind FSH.	Nitrogen	93-94	follicle stimulating hormone receptor	Homo sapiens	147-151
7709726-2	1995	When the cerebellar slice was perfused with a glucose-free physiological medium equilibrated with a 95% N2/5% CO2 gas mixture (in vitro ischemic medium), a large [Ca2+]i elevation was region-specifically induced in the molecular layer of the cerebellar cortex (a dendritic field of Purkinje cells).	Nitrogen	104-106	carbonic anhydrase 2	Homo sapiens	163-166
7748973-1	1995	Prolidase (EC: 3.4.13.9) catalyses the hydrolysis of the peptide bond involving the imino nitrogen of proline or hydroxyproline.	Nitrogen	90-98	peptidase D	Homo sapiens	0-9
7775382-1	1995	Our previous studies showed that the N-linked sugar chains of most bovine glycoproteins from milk fat globule membranes (MFGM) contain the GalNAc beta 1--&gt;4GlcNAc group [Sato et al.	Nitrogen	37-38	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	121-125
7526155-3	1994	This mutation defines a new gene, designated MID1, which encodes an N-glycosylated, integral plasma membrane protein with 548 amino acid residues.	Nitrogen	68-69	Mid1p	Saccharomyces cerevisiae S288C	45-49
7955103-4	1994	N-Hydroxylation, an obligatory initial step in the activation of 2-AAF into electrophilic DNA-binding metabolites is catalyzed predominantly by cytochrome P450 (CYP)1A2, an isozyme present in normal rat liver.	Nitrogen	0-1	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	144-168
8038191-6	1994	In conclusion, BBB and choroid plexus GLUT1 are subject to differential N-linked glycosylation with the protein having an N-linked carbohydrate side chain of higher molecular mass at the BBB in comparison to the choroid plexus.	Nitrogen	72-73	solute carrier family 2 member 1	Homo sapiens	38-43
7956732-4	1994	Together, these data indicate that N-hydroxylation of DDS and MADDS in rat liver microsomes from untreated male rats is catalyzed by CYP2C6/2C11.	Nitrogen	35-36	cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1	Rattus norvegicus	133-139
8033884-7	1994	The results also suggest that the N-acetyl NH group in N-acetyllactosamine, as well as the hydroxyl group at position C-2 in methyl beta-lactoside, are involved in a polar interaction with neutral groups of the combining site.	Nitrogen	34-35	complement C2	Bos taurus	118-121
8185577-5	1994	We speculate that the N-glycosylation difference affects the interaction between CD45 and other factors involved in signal transduction leading to modulation of leukocyte proliferation.	Nitrogen	22-23	protein tyrosine phosphatase receptor type C	Homo sapiens	81-85
15582466-3	2005	N-alkyl derivatives (2, 3, 4) of phenothiazine (1) have previously been found to inhibit only BuChE in a mechanism involving pi-pi interaction between the phenothiazine tricyclic ring system and aromatic residues in the active site gorge.	Nitrogen	0-1	butyrylcholinesterase	Homo sapiens	94-99
15617814-6	2005	It should be noted that Ac-Pro-NMe2 has higher rotational barriers for the cis-trans isomerization of the Ac-Pro peptide bond than Ac-Pro-NHMe in the gas phase and in solutions, which could be due to the lack of the intramolecular hydrogen bond between prolyl nitrogen and carboxyl N-H group for the transition state of Ac-Pro-NMe2.	Nitrogen	260-268	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	31-35
15617814-6	2005	It should be noted that Ac-Pro-NMe2 has higher rotational barriers for the cis-trans isomerization of the Ac-Pro peptide bond than Ac-Pro-NHMe in the gas phase and in solutions, which could be due to the lack of the intramolecular hydrogen bond between prolyl nitrogen and carboxyl N-H group for the transition state of Ac-Pro-NMe2.	Nitrogen	31-32	NME/NM23 nucleoside diphosphate kinase 2	Homo sapiens	327-331
15632429-3	2005	beta-Galactosidase activity fostered by the promoter of GDH1/3, which encode anabolic enzymes of nitrogen metabolism, was altered in an MRG19 disruptant.	Nitrogen	97-105	glutamate dehydrogenase (NADP(+)) GDH1	Saccharomyces cerevisiae S288C	56-62
15591615-1	2004	The activity of glutamate dehydrogenase (GDH), an important enzyme in carbon and nitrogen metabolism, is routinely assayed by photometry.	Nitrogen	81-89	glutamate dehydrogenase 1	Homo sapiens	16-39
15591615-1	2004	The activity of glutamate dehydrogenase (GDH), an important enzyme in carbon and nitrogen metabolism, is routinely assayed by photometry.	Nitrogen	81-89	glutamate dehydrogenase 1	Homo sapiens	41-44
15714240-3	2004	The protein is 20.9% identical to the Saccharomyces cerevisiae Gpr1p receptor that signals both glucose availability and nitrogen limitation.	Nitrogen	121-129	Gpr1p	Saccharomyces cerevisiae S288C	63-68
15477386-9	2004	Moreover, Slc26a4(-/-) mice had evidence of relative vascular volume depletion because they had a higher arterial pH, hematocrit, and blood urea nitrogen than wild-type mice.	Nitrogen	145-153	solute carrier family 26, member 4	Mus musculus	10-17
15554639-4	2004	Ru2(dpf)4(NO) undergoes reversible one-electron reductions under N2 at E1/2=0.06 and -1.24 V in CH2Cl2, 0.1 M TBABr.	Nitrogen	65-67	doublecortin domain containing 2	Homo sapiens	0-3
15554639-7	2004	Ru2(dpf)4(NO)2 displays a reversible one-electron reduction at E1/2=-1.24 V versus SCE and an irreversible reduction at Epc=-1.96 V in CH2Cl2, 0.1 M TBAP under N2.	Nitrogen	160-162	doublecortin domain containing 2	Homo sapiens	0-3
15337741-9	2004	MOX is N-glycosylated, is tightly membrane-associated, and forms oligomers that are not disulfide-linked.	Nitrogen	7-8	monooxygenase DBH like 1	Homo sapiens	0-3
15655705-4	2004	DPP IV cleavage generates N-terminally truncated metabolites (GLP-1 (9-36) amide / (9-37) and GIP (3-42)), which are the major circulating forms.	Nitrogen	26-27	dipeptidyl peptidase 4	Homo sapiens	0-6
15368218-10	2004	A statistical analysis showed that n-Bone% with OCP/BMP was significantly higher than that with OCP at both time points, whereas the difference in n-Bone% between OCP/BMP 10 microg and OCP/BMP 1 microg was not significant.	Nitrogen	35-36	bone morphogenetic protein 1	Homo sapiens	52-55
12232201-0	1994	Isoprene Emission from Velvet Bean Leaves (Interactions among Nitrogen Availability, Growth Photon Flux Density, and Leaf Development).	Nitrogen	62-70	brain expressed associated with NEDD4 1	Homo sapiens	30-34
15493939-1	2004	Reduction of the five-coordinate iron(II) dihalide complexes (iPrPDI)FeX2 (iPrPDI = ((2,6-CHMe2)2C6H3N=CMe)2C5H3N; X = Cl, Br) with sodium amalgam under 1 atm of dinitrogen afforded the square pyramidal, high spin iron(0) bis(dinitrogen) complex (iPrPDI)Fe(N2)2.	Nitrogen	162-172	stabilin 2	Homo sapiens	69-73
8166649-9	1994	In addition, the N-glycosylation of IgA1 was remarkably consistent within the group of normal individuals.	Nitrogen	17-18	immunoglobulin heavy constant alpha 1	Homo sapiens	36-40
15493939-1	2004	Reduction of the five-coordinate iron(II) dihalide complexes (iPrPDI)FeX2 (iPrPDI = ((2,6-CHMe2)2C6H3N=CMe)2C5H3N; X = Cl, Br) with sodium amalgam under 1 atm of dinitrogen afforded the square pyramidal, high spin iron(0) bis(dinitrogen) complex (iPrPDI)Fe(N2)2.	Nitrogen	257-259	stabilin 2	Homo sapiens	69-73
15456536-5	2004	RESULTS: Ulinastatin significantly reduced the increase in blood urea nitrogen and creatinine produced by renal ischemia-reperfusion, suggesting an improvement in renal function.	Nitrogen	70-78	alpha-1-microglobulin/bikunin precursor	Rattus norvegicus	9-20
8139573-8	1994	The expression of YGP1 also responds to the depletion of nitrogen and phosphate, indicating a general response to nutrient deprivation.	Nitrogen	57-65	Ygp1p	Saccharomyces cerevisiae S288C	18-22
15448639-1	2004	Two different roles for SNM (sensitive to nitrogen mustard) proteins have already been described: the SNM1/PSO2-related proteins are involved in the repair of the interstrand crosslink (ICL) and the ARTEMIS proteins are involved in the V(D)J recombination process.	Nitrogen	42-50	DNA repair metallo-beta-lactamase family protein	Arabidopsis thaliana	102-106
8079379-2	1994	These steroid dehydrogenases are also homologous to human 15-hydroxyprostaglandin dehydrogenase and to proteins found in Rhizobia, bacteria that form nitrogen-fixing nodules in the roots of legumes.	Nitrogen	150-158	carbonyl reductase 1	Homo sapiens	58-95
15301945-2	2004	The interaction between Mb and HMS was investigated by using Fourier transfer infrared spectroscopy, nitrogen adsorption isotherm, and cyclic voltammetry.	Nitrogen	101-109	myoglobin	Homo sapiens	24-26
15327321-2	2004	The nucleophilic substitution of N2 in benzenediazonium ion 1 by one H2O molecule to form protonated phenol 2 has been studied with ab initio (RHF, MP2, QCISD(T)//MP2) and hybrid density functional (B3LYP) methods.	Nitrogen	33-35	tryptase pseudogene 1	Homo sapiens	148-151
15327321-2	2004	The nucleophilic substitution of N2 in benzenediazonium ion 1 by one H2O molecule to form protonated phenol 2 has been studied with ab initio (RHF, MP2, QCISD(T)//MP2) and hybrid density functional (B3LYP) methods.	Nitrogen	33-35	tryptase pseudogene 1	Homo sapiens	163-166
15311923-1	2004	Cobyrinic acid a,c-diamide synthetase from Salmonella typhimurium (CbiA) is the first glutamine amidotransferase in the anaerobic biosynthetic pathway of vitamin B(12) and catalyzes the ATP-dependent synthesis of cobyrinic acid a,c-diamide from cobyrinic acid using either glutamine or ammonia as the nitrogen source.	Nitrogen	301-309	cobyrinic acid a,c-diamide synthase	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2	67-71
15291623-4	2004	All of the complexes discussed here have the nitrogen end of the HCN pointing towards the magnesium clusters.	Nitrogen	45-53	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	65-68
15291623-8	2004	Significant charge transfer is observed in the case of HCN-Mg4, indicative of charge donation from the lone pair on the nitrogen of HCN into the lowest unoccupied molecular orbital of the Mg4.	Nitrogen	120-128	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	55-58
15291623-8	2004	Significant charge transfer is observed in the case of HCN-Mg4, indicative of charge donation from the lone pair on the nitrogen of HCN into the lowest unoccupied molecular orbital of the Mg4.	Nitrogen	120-128	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	132-135
15044389-5	2004	Using the osteosarcoma-derived MHH-ES1 cell line we successfully expressed a recombinant BM-40 that bears at least in part the bone-specific high-mannose N-glycosylation in addition to complex type and hybrid structures.	Nitrogen	154-155	secreted protein acidic and cysteine rich	Homo sapiens	89-94
15183057-4	2004	Conserved N-glycosylation sites were placed on the gp120-3D model.	Nitrogen	10-11	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	51-56
15135306-5	2004	A strong correlation (r(2) =0.92 ) was observed between N-glucuronidating activities toward TAM and trifluoperazine, a probe substrate for human UDP-glucuronosyltransferase (UGT) 1A4, in human liver microsomes from eight donors (five females, three males).	Nitrogen	56-57	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	145-182
15135306-7	2004	Only UGT1A4 catalyzed the N-linked glucuronidation of TAM among recombinant UGTs (UGT1A1, UGT1A3, UGT1A4, UGT1A6, UGT1A9, UGT2B4, UGT2B7, UGT2B15, and UGT2B17) expressed in insect cells.	Nitrogen	26-27	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	5-11
15135306-8	2004	Apparent K(m) values for TAM N-glucuronidation by human liver microsomes and recombinant UGT1A4 were 35.8 and 32.4 microM, respectively.	Nitrogen	29-30	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	89-95
15037553-4	2004	Two enzymes are potentially able to release Ac-SDKP from thymosin-beta4: prolyl oligopeptidase (POP) and endoproteinase asp-N.	Nitrogen	124-125	thymosin beta 4, X-linked	Rattus norvegicus	57-71
15209355-0	2004	N-palmitoylation of the radioprotective domain of interleukin-1 affords inhibition of LPS-induced nitric oxide generation.	Nitrogen	0-1	interleukin 1 alpha	Homo sapiens	50-63
15065850-5	2004	NMR titration of (15)N-labeled wild-type CaaD yielded pK(a) values of 9.3 and 11.1 for the N-terminal prolines, while the fully active but unstable alphaP1A mutant showed a pK(a) of 9.7 (for the betaPro-1), implicating betaPro-1 as the acid catalyst, which may protonate C-2 of the substrate.	Nitrogen	0-1	complement C2	Homo sapiens	271-274
14722111-0	2004	Structure-function analysis of the human sialyltransferase ST3Gal I: role of n-glycosylation and a novel conserved sialylmotif.	Nitrogen	12-13	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	Homo sapiens	59-67
15126393-7	2004	Nitrogen-source control of AGP1 induction is mediated by the GATA factor Gln3, likely acting through adjacent 5"-GATA-3" sequences, to amplify the positive effect of UAS(AA).	Nitrogen	0-8	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	73-77
15039314-10	2004	These data demonstrate that N-linked glycosylation of C1INH is essential to mediate its interaction with the LPA moiety of LPS and to protect mice from endotoxin shock.	Nitrogen	28-29	serine (or cysteine) peptidase inhibitor, clade G, member 1	Mus musculus	54-59
15033560-7	2004	Genetic sequence analysis combined with mutagenesis studies on clonal, chimeric viruses derived from CC1/85 and the PTCA variant showed that the most important changes were in the V1/V2 loop structure, one of them involving the loss of an N-linked glycosylation site.	Nitrogen	239-240	C-C motif chemokine ligand 14	Homo sapiens	101-107
14679193-3	2004	At the other end of that cascade is Gln3, one of two transcriptional activators responsible for most nitrogen catabolic gene expression.	Nitrogen	101-109	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	36-40
8308865-5	1994	The specificity and affinity of CNAD for ADH are likely due to coordination of the zinc cation at the ADH catalytic site by the CNAD pyridine nitrogen.	Nitrogen	142-150	aldo-keto reductase family 1 member A1	Homo sapiens	41-44
8308865-5	1994	The specificity and affinity of CNAD for ADH are likely due to coordination of the zinc cation at the ADH catalytic site by the CNAD pyridine nitrogen.	Nitrogen	142-150	aldo-keto reductase family 1 member A1	Homo sapiens	102-105
8308865-8	1994	In this analogue, displacement of the pyridine nitrogen to the opposite side of the ring removes the specificity for ADH.	Nitrogen	47-55	aldo-keto reductase family 1 member A1	Homo sapiens	117-120
14679193-4	2004	When nitrogen is in excess, Tor1/2 are active, and Gln3 is phosphorylated and localizes to the cytoplasm.	Nitrogen	5-13	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	51-55
14679193-6	2004	The observations that Gln3 also accumulates in the nuclei of cells provided with poor nitrogen sources or during nitrogen starvation has led to the conclusion that Tor1/2 control intracellular Gln3 localization and NCR-sensitive transcription by regulating Gln3 phosphorylation/dephosphorylation.	Nitrogen	86-94	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	22-26
14679193-6	2004	The observations that Gln3 also accumulates in the nuclei of cells provided with poor nitrogen sources or during nitrogen starvation has led to the conclusion that Tor1/2 control intracellular Gln3 localization and NCR-sensitive transcription by regulating Gln3 phosphorylation/dephosphorylation.	Nitrogen	113-121	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	22-26
8276871-5	1994	The ectodomain of chicken syndecan-4 core protein contains three potential sites for glycosaminoglycan attachment, two sites for N-glycosylation, and lacks a dibasic protease cleavage site proximal to the membrane-spanning region found in other syndecan family members.	Nitrogen	129-130	syndecan 4	Gallus gallus	26-36
14679193-9	2004	(ii) Gln3-Myc(13) is hyperphosphorylated during nitrogen and carbon starvation, but this uniform response does not correlate with Gln3 intracellular localization.	Nitrogen	48-56	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	5-9
14679193-11	2004	These data suggest that rapamycin treatment and growth with poor nitrogen sources bring about nuclear accumulation of Gln3 but likely do so by different mechanisms or by a common mechanism involving molecules other than Gln3 and/or other than the levels of Gln3-Myc(13) phosphorylation thus far detected by others and ourselves.	Nitrogen	65-73	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	118-122
14981239-1	2004	Synaptic exocytosis requires the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins syntaxin 1, SNAP-25, and synaptobrevin (VAMP).	Nitrogen	41-42	synaptosome associated protein 25	Homo sapiens	132-139
8304478-2	1994	Compared with rats administered vehicle, rats administered 20 micrograms HGF subcutaneously 30 min postischemia had significantly lower serum creatinine and blood urea nitrogen levels over the course of 7 days postocclusion, enhanced insulin clearances measured on day 2 postocclusion, reduced mortality, and much less injury evident by examination of kidney histologies 7 days postinjury.	Nitrogen	168-176	hepatocyte growth factor	Rattus norvegicus	73-76
7987008-4	1994	The rhesus macaque beta 1-adrenergic receptor contains conserved sites for potential N-linked glycosylation and cAMP-dependent protein kinase phosphorylation identified within the human and rat receptors, but differs in the structure and length of the third cytoplasmic loop.	Nitrogen	85-86	beta-1 adrenergic receptor	Macaca mulatta	19-45
15148691-9	2004	On the other hand, GTPCH mRNA concentrations in renal tissues were significantly higher in the LPS group as compared with the N/S group.	Nitrogen	27-28	GTP cyclohydrolase 1	Mus musculus	19-24
7505013-8	1993	Treatment with N-Glycanase eliminated this observed difference in molecular weight, indicating that it reflected differences in N-glycosylation of CD44 on activated B cells.	Nitrogen	15-16	CD44 molecule (Indian blood group)	Homo sapiens	147-151
8243281-3	1993	All three PAM proteins are N-glycosylated, and PAM-1 also has sialylated O-linked oligosaccharide.	Nitrogen	27-28	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	10-13
14592810-6	2004	The immunoreactive band migrated as a 140-kDa protein after N-deglycosylation, consistent with the predicted molecular size of the SLC4A10 gene product.	Nitrogen	60-61	solute carrier family 4 member 10	Rattus norvegicus	131-138
8251521-5	1993	In a reconstituted systems, P-450 UT-7 and UT-7b catalyzed lidocaine 3-hydroxylation and N-deethylation in the presence of the 29 k-protein.	Nitrogen	89-90	cytochrome P450, family 2, subfamily d, polypeptide 1	Rattus norvegicus	28-38
14976234-8	2004	In Arabidopsis, the addition of allantoin to the medium as a sole source of nitrogen resulted in the up-regulation of the AtALN gene.	Nitrogen	76-84	allantoinase	Arabidopsis thaliana	122-127
8251521-9	1993	The activities of debrisoquine 4-hydroxylation as well as lidocaine 3-hydroxylation and N-deethylation in a reconstituted system with P-450 UT-7 without 29 k-protein were one-fifth of those of P-450 UT-7 containing 29 k-protein at the same substrate concentration.	Nitrogen	88-89	cytochrome P450, family 2, subfamily d, polypeptide 1	Rattus norvegicus	134-144
8117918-3	1993	The cDNA-expressed FMO3 was used to investigate the regio- and stereoselective N- and S-oxygenation of a number of tertiary amines and sulfides, respectively.	Nitrogen	6-7	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	19-23
14970177-3	2004	Here we show that vIL-6 is N-linked glycosylated at N78 and N89 and demonstrate that N-linked glycosylation at site N89 of vIL-6 markedly enhances binding to gp130, signaling through the JAK1-STAT1/3 pathway and functions in a cytokine-dependent cell proliferation bioassay.	Nitrogen	27-28	interleukin 6 cytokine family signal transducer	Homo sapiens	158-163
14663547-2	2004	A first set of experiments shows that high flow rates of N(2) as curtain gas can induce unfolding of cytochrome c (cyt c) and myoglobin (Mb), under conditions in which the stability of the native protein structure has already been reduced by acidification.	Nitrogen	57-61	myoglobin	Homo sapiens	126-135
8229211-3	1993	Our results reveal that syp II, similar to syp I, is an abundant, N-glycosylated membrane protein that is part of a heteromultimeric complex in synaptic vesicle membranes.	Nitrogen	66-67	synaptophysin	Rattus norvegicus	24-27
7510882-7	1993	These data demonstrate that the CCKA receptors in the pancreas and on gallbladder smooth muscle possess similar affinities for the various N alpha-carboxyacyl analogues of CCK-7 and CCK-8 with a substituted Gly and provide further evidence that the CCKA receptors in gallbladder and pancreas cannot be distinguished pharmacologically.	Nitrogen	139-140	cholecystokinin	Cavia porcellus	32-35
14663547-2	2004	A first set of experiments shows that high flow rates of N(2) as curtain gas can induce unfolding of cytochrome c (cyt c) and myoglobin (Mb), under conditions in which the stability of the native protein structure has already been reduced by acidification.	Nitrogen	57-61	myoglobin	Homo sapiens	137-139
7510882-7	1993	These data demonstrate that the CCKA receptors in the pancreas and on gallbladder smooth muscle possess similar affinities for the various N alpha-carboxyacyl analogues of CCK-7 and CCK-8 with a substituted Gly and provide further evidence that the CCKA receptors in gallbladder and pancreas cannot be distinguished pharmacologically.	Nitrogen	139-140	cholecystokinin	Cavia porcellus	172-175
14966466-6	2004	Immunohistochemical studies were also performed with the use of monoclonal antibodies that react specifically with the N-sulfated portion of the GAG chain of HSPG and agrin, a major core protein of HSPG in glomerular basement membrane (GBM).	Nitrogen	119-120	syndecan 1	Rattus norvegicus	158-162
8368872-8	1993	While these data showed that under N-deprived conditions methanogenesis was inhibited to a greater extent by these compounds, it also suggests that N-deprived conditions may have facilitated the establishment of a 2-AP metabolizing consortium.	Nitrogen	148-149	serpin family F member 2	Homo sapiens	212-218
8353847-6	1993	Rates of N-acetylation by NAT1 and NAT2 were considerably lower for heterocyclic arylamines such as 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ), particularly those (e.g. IQ) with steric hindrance to the exocyclic amino group.	Nitrogen	9-10	N-acetyltransferase 2	Homo sapiens	35-39
14966466-6	2004	Immunohistochemical studies were also performed with the use of monoclonal antibodies that react specifically with the N-sulfated portion of the GAG chain of HSPG and agrin, a major core protein of HSPG in glomerular basement membrane (GBM).	Nitrogen	119-120	syndecan 1	Rattus norvegicus	198-202
8335910-3	1993	hsp70 RY is 701 amino acids long, has the characteristic N-terminal ATP-binding domain and the C-terminal peptide binding domain, and contains four potential N-glycosylation sites.	Nitrogen	57-58	heat shock protein family A (Hsp70) member 4	Homo sapiens	0-8
14966466-9	2004	Immunohistochemical studies revealed that staining for N-sulfated GAG chains of HSPG on GBM was markedly reduced on day 10 in PAN-treated rats but that staining for agrin was unchanged.	Nitrogen	55-56	syndecan 1	Rattus norvegicus	80-84
14657246-1	2004	We have reported that p22, an N-myristoylated EF-hand Ca(2+)-binding protein, associates with microtubules and plays a role in membrane trafficking.	Nitrogen	30-31	calcineurin like EF-hand protein 1	Homo sapiens	22-25
8510918-6	1993	The use of N- and C-terminal truncations of this segment demonstrated that as few as 96 amino acids were required for active repression by GAL4-WT1 hybrid proteins in NIH3T3 fibroblasts.	Nitrogen	11-12	galectin 4	Homo sapiens	139-143
14757367-5	2004	The release of TNF-alpha from SAA-stimulated neutrophils is strongly suppressed by the addition of the antioxidants N-acetyl-L-cysteine, alpha-mercaptoethanol, glutathione, the antiinflammatory dexamethasone and the compounds wortmannin (a PI3K inhibitor), PD98059 (a MEK-1 inhibitor) and SB203580 (a p38 inhibitor).	Nitrogen	16-17	mitogen-activated protein kinase kinase 1	Homo sapiens	268-273
7916636-5	1993	Human, monkey and rat renal/pancreatic kallikrein genes evolve with a N-glycosylation containing domain (aa 81-87) which is absent in porcine and is non-glycosylable in mice.	Nitrogen	70-71	kallikrein related peptidase 4	Homo sapiens	39-49
7916636-6	1993	Only human kallikrein evolves with an additional Thr-108 and with a N-glycosylation site at aa-141.	Nitrogen	68-69	kallikrein related peptidase 4	Homo sapiens	11-21
15331933-8	2004	By 6 weeks the BSA + BMP-7 group compared to the BSA + placebo group had a nonsignificant decrease in blood urea nitrogen (40 +/- 13 vs. 46 +/- 11 mg/dl), total kidney collagen (10.8 +/- 2.1 vs. 12.2 +/- 3.5 microg/kidney), fibronectin interstitial area (23 +/- 4 vs. 25 +/- 8%) and collagen III interstitial area (22 +/- 6 vs. 28 +/- 7%).	Nitrogen	113-121	bone morphogenetic protein 7	Rattus norvegicus	21-26
8392711-4	1993	The predicted signal sequences and N-linked glycosylation sites in the US3 products were confirmed using expression in reticulocyte lysates containing microsomal membranes.	Nitrogen	35-36	membrane glycoprotein US3	Human betaherpesvirus 5	71-74
15032878-5	2004	(1) Nitrogen deprivation caused up-regulation of psbA, psbC, petA, petG and clpP transcripts, down-regulation of psbG, psbK and ndhA, a five-fold increase in ascorbic acid, a severe drop in CAT and APX activities, although cat1 mRNA levels were increased in young and old leaves.	Nitrogen	4-12	ATP-dependent Clp protease proteolytic subunit	Arabidopsis thaliana	76-80
7685904-3	1993	FKB2 mRNA levels are elevated in cells blocked in N-glycosylation--i.e., in wild-type cells treated with tunicamycin and in the sec53-6 mutant grown at the nonpermissive temperature.	Nitrogen	7-8	peptidylprolyl isomerase family protein FPR2	Saccharomyces cerevisiae S288C	0-4
15032878-5	2004	(1) Nitrogen deprivation caused up-regulation of psbA, psbC, petA, petG and clpP transcripts, down-regulation of psbG, psbK and ndhA, a five-fold increase in ascorbic acid, a severe drop in CAT and APX activities, although cat1 mRNA levels were increased in young and old leaves.	Nitrogen	4-12	photosystem II protein K	Arabidopsis thaliana	119-123
15032878-5	2004	(1) Nitrogen deprivation caused up-regulation of psbA, psbC, petA, petG and clpP transcripts, down-regulation of psbG, psbK and ndhA, a five-fold increase in ascorbic acid, a severe drop in CAT and APX activities, although cat1 mRNA levels were increased in young and old leaves.	Nitrogen	4-12	catalase 2	Arabidopsis thaliana	190-193
15032878-5	2004	(1) Nitrogen deprivation caused up-regulation of psbA, psbC, petA, petG and clpP transcripts, down-regulation of psbG, psbK and ndhA, a five-fold increase in ascorbic acid, a severe drop in CAT and APX activities, although cat1 mRNA levels were increased in young and old leaves.	Nitrogen	4-12	catalase 1	Arabidopsis thaliana	223-227
8510099-2	1993	A family of N-methylated and N,N-dimethylated alkyl and arylalkylamines was prepared and more than half of the analogues were shown to be time-dependent pseudo-first-order inhibitors of monoamine oxidase-B.	Nitrogen	12-13	monoamine oxidase B	Homo sapiens	186-205
14691230-0	2004	N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding.	Nitrogen	0-1	dipeptidyl peptidase 4	Homo sapiens	26-49
8486695-19	1993	Metabolic labeling combined with immunoprecipitation methods using antibodies raised against synthetic peptides of PMP22 reveal that Schwann cells generate the protein from an 18-kDa precursor form which is post-translationally modified by N-linked glycosylation.	Nitrogen	240-241	peripheral myelin protein 22	Rattus norvegicus	115-120
14691230-0	2004	N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding.	Nitrogen	0-1	dipeptidyl peptidase 4	Homo sapiens	51-55
14691230-3	2004	Crystallographic studies on DPPIV reveal clear N-linked glycosylation of nine Asn residues in DPPIV.	Nitrogen	47-48	dipeptidyl peptidase 4	Homo sapiens	28-33
14691230-3	2004	Crystallographic studies on DPPIV reveal clear N-linked glycosylation of nine Asn residues in DPPIV.	Nitrogen	47-48	dipeptidyl peptidase 4	Homo sapiens	94-99
8504797-7	1993	Interestingly, the sequence analysis of beta-ETF protein identifies a 26.3% identity with the Fix A gene product of the nitrogen-fixing bacterium Azorhizobium caulinodans.	Nitrogen	120-128	electron transfer flavoprotein subunit beta	Homo sapiens	40-48
14691230-6	2004	Crystallographic and biochemical data demonstrate that N-linked glycosylation of DPPIV does not contribute significantly to its peptidase activity.	Nitrogen	55-56	dipeptidyl peptidase 4	Homo sapiens	81-86
8496826-5	1993	Incubating TPH from THM-treated rats with dithiothreitol under nitrogen failed to reverse the decrease in enzyme activity induced by THM treatment.	Nitrogen	63-71	tryptophan hydroxylase 1	Rattus norvegicus	11-14
14651673-3	2003	In this study, we determined the percentage contribution of the three CYPs (CYP2C9, CYP2E1 and CYP3A4) to TMO N-demethylation.	Nitrogen	110-111	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	76-82
12867358-8	2003	These results suggest that Asn591 and/or N-glycosylation is critical for transport activity in NaSi-1.	Nitrogen	41-42	solute carrier family 13 member 1 S homeolog	Xenopus laevis	95-101
8318676-5	1993	However the secreted MCP-3 protein differs from MCP-1 in being N-glycosylated.	Nitrogen	63-64	C-C motif chemokine ligand 7	Homo sapiens	21-26
8420952-2	1993	To address these problems, a sequence of 29 amino acids encoding an internal N-glycosylation site of rabbit cytochrome P450 2C2 was attached to the N terminus of cytochrome P450 2C1.	Nitrogen	77-78	LOW QUALITY PROTEIN: cytochrome P450 2C1	Oryctolagus cuniculus	162-181
12827295-8	2003	Using a series of polyamine analogues, it was found that the most potent inducers of PAOh1/SMO possessed multiple three-carbon linkers between nitrogens, as typified by N1,N11-bis(ethyl)norspermine.	Nitrogen	143-152	smoothened, frizzled class receptor	Homo sapiens	91-94
8381348-7	1993	Thus, this MyoD/Myf-5-like protein appears to promote sexual differentiation by modulating responses to decreases in cAMP, a part of the nitrogen starvation signal that induces differentiation.	Nitrogen	137-145	myogenic factor 5	Homo sapiens	16-21
14689683-7	2003	IgA nephropathy patients display increased or borderline serum IgA levels; increased serum levels of IgA fraction with degalactosylated O-linked side sugar chains; increased serum levels of anti-N-acetylgalactosamine antibodies; increased levels of circulating immune complexes composed of IgA1 complexed with IgG or IgA1; increased serum levels of circulating complexes composed of IgA and fibronectin; and frequent occurrence of the rheumatoid IgA factor.	Nitrogen	195-196	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	0-3
14522078-4	2003	The human beta(3)AR expressed in yeast is N-glycosylated but not phosphorylated.	Nitrogen	42-43	adrenoceptor beta 3	Homo sapiens	10-19
8432340-10	1993	The alpha 2,6-sialyltransferase newly expressed in the inner segments on P16 appears to sialylate the Gal beta 1, 4GlcNAc residue of N-glycosidically linked glycoconjugates of the IPM, resulting in the change of lectin staining profiles.	Nitrogen	118-119	cyclin-dependent kinase inhibitor 2A	Rattus norvegicus	73-76
8225481-5	1993	The data obtained in the human system show that N-hydroxy-IQ, formed by cytochrome P450, binds poorly to DNA, whereas more efficient binding occurs in the presence of NAT1 and most efficient binding in presence of NAT2.	Nitrogen	48-49	N-acetyltransferase 2	Homo sapiens	214-218
14581628-4	2003	Transcripts of Ntdin are induced by sulfate or nitrate but not by phosphate, suggesting its involvement in sulfur and nitrogen metabolism.	Nitrogen	118-126	thiosulfate sulfurtransferase 16, chloroplastic-like	Nicotiana tabacum	15-20
8081722-4	1993	In the first model, the beta-adrenergic receptor is used as a reference with the catechol moieties of dopamine interacting with two Ser residues in TM5, and the Asp residue in TM3 interacting with the protonated nitrogen of dopamine.	Nitrogen	212-220	tropomyosin 3	Homo sapiens	176-179
14504666-7	2003	N-desulfated heparin significantly inhibited the adhesion of spleen cells and purified T lymphocytes isolated from the liver injured mice to either type I collagen or fibronectin but not to laminin.	Nitrogen	0-1	fibronectin 1	Mus musculus	167-178
1334528-1	1992	Nitrogen mustard (HN2) mutagenesis of a plasmid-borne copy of the Saccharomyces cerevisiae SUP4-o gene was examined in a repair-proficient yeast strain and isogenic derivatives defective for excision (rad1) or DNA double-strand break (rad52) repair.	Nitrogen	0-8	SUP4	Saccharomyces cerevisiae S288C	91-95
12740382-1	2003	Lipoprotein lipase (LPL) is a non-covalent, homodimeric, N-glycosylated enzyme important for metabolism of blood lipids.	Nitrogen	57-58	lipoprotein lipase	Homo sapiens	0-18
1509880-1	1992	Nasal continuous positive airway pressure (N-CPAP) has been used in infants with decreased lung compliance for increasing the functional residual capacity (FRC), decreasing the work of breathing and improving the PaO2/PAO2 (arterial-alveolar PO2 ratio) without intubation.	Nitrogen	0-1	centromere protein J	Homo sapiens	45-49
12740382-1	2003	Lipoprotein lipase (LPL) is a non-covalent, homodimeric, N-glycosylated enzyme important for metabolism of blood lipids.	Nitrogen	57-58	lipoprotein lipase	Homo sapiens	20-23
12888867-2	2003	PAI-1 has 3 potential sites for N-linked glycosylation.	Nitrogen	32-33	serpin family E member 1	Homo sapiens	0-5
1569960-0	1992	Expression of the DAL80 gene, whose product is homologous to the GATA factors and is a negative regulator of multiple nitrogen catabolic genes in Saccharomyces cerevisiae, is sensitive to nitrogen catabolite repression.	Nitrogen	118-126	Dal80p	Saccharomyces cerevisiae S288C	18-23
12783264-1	2003	Glutamine synthetase, an enzyme generally associated with ammonia detoxication in the vertebrate brain and with hepatic nitrogen turnover in mammals, shows substantial activities in the gastrointestinal tract of teleostean fishes.	Nitrogen	120-128	glutamine synthetase	Oncorhynchus mykiss	0-20
1374031-2	1992	The N-linked carbohydrate chains of the beta subunit of human chorionic gonadotropin (hCG-beta) isolated from the culture fluid of the choriocarcinoma cell line BeWo were released enzymatically by peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase F. Subsequently, the O-linked oligosaccharides were split off from the N-deglycosylated protein by mild alkaline borohydride treatment.	Nitrogen	4-5	chorionic gonadotropin subunit beta 3	Homo sapiens	86-94
12805451-7	2003	The R(+) Env protein induced syncytia in XC cells expressing a mutant mCAT1 lacking both of two N glycosylation sites, and tunicamycin treatment suppressed syncytium formation by R(+) Env in those cells.	Nitrogen	96-97	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	70-75
1536571-0	1992	Evaluation of human N-linked glycosylation sites in murine granulocyte-macrophage colony-stimulating factor.	Nitrogen	20-21	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	59-107
14592558-5	2003	In both species, administration of COX inhibitors resulted in redistribution of blood flow from hypoxic alveoli (N2-ventilated lung) to the well-oxygenated alveoli (O2-ventilated lung) and an increase in arterial oxygen tension, i.e., a COX-mediated AA metabolite or metabolites opposed hypoxic pulmonary vasoconstriction (HPV), but, by virtue of this activity, prevented optimal matching of ventilation with perfusion.	Nitrogen	113-115	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	35-38
1587794-6	1992	Two N-glycosylation sites were found in the extracellular region of MMGL, corresponding to the heavy N-glycosylation in the native MMGL.	Nitrogen	4-5	C-type lectin domain containing 10A	Rattus norvegicus	68-72
1587794-6	1992	Two N-glycosylation sites were found in the extracellular region of MMGL, corresponding to the heavy N-glycosylation in the native MMGL.	Nitrogen	4-5	C-type lectin domain containing 10A	Rattus norvegicus	131-135
1587794-6	1992	Two N-glycosylation sites were found in the extracellular region of MMGL, corresponding to the heavy N-glycosylation in the native MMGL.	Nitrogen	101-102	C-type lectin domain containing 10A	Rattus norvegicus	68-72
1587794-6	1992	Two N-glycosylation sites were found in the extracellular region of MMGL, corresponding to the heavy N-glycosylation in the native MMGL.	Nitrogen	101-102	C-type lectin domain containing 10A	Rattus norvegicus	131-135
12796300-2	2003	Among other effects, rapamycin treatment results in the nuclear localization of the global nitrogen activators Gln3p and Nil1p/Gat1p, which leads to expression of nitrogen assimilation genes.	Nitrogen	91-99	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	111-116
1744078-10	1991	Analysis of this mutant revealed two functions for this region: it prevents N-linked glycosylation of the serine protease domain and it allows the PrB precursor to be processed by proteinase A.	Nitrogen	76-77	proteinase A	Saccharomyces cerevisiae S288C	180-192
12796300-2	2003	Among other effects, rapamycin treatment results in the nuclear localization of the global nitrogen activators Gln3p and Nil1p/Gat1p, which leads to expression of nitrogen assimilation genes.	Nitrogen	163-171	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	111-116
12730686-5	2003	CypA Arg55 guanidinium group probably facilitates catalysis by anchoring the substrate proline oxygen and stabilizing sp3 hybridization of the proline nitrogen in the transition state.	Nitrogen	151-159	peptidylprolyl isomerase A	Homo sapiens	0-4
1946375-4	1991	In vitro translation of NaPi-1/complementary RNA in the presence of pancreatic microsomes indicated NaPi-1 to be a glycosylated protein; four potential N-glycosylation sites are present in the amino acid sequence.	Nitrogen	24-25	sodium-dependent phosphate transport protein 1	Oryctolagus cuniculus	100-106
1717457-9	1991	The CHO cell-derived SCF is about 30% carbohydrate by weight, with both N-linked and O-linked sugar.	Nitrogen	72-73	KIT ligand	Homo sapiens	21-24
12706347-5	2003	Using site-directed mutagenesis, mutants were constructed to eliminate this highly conserved N-glycosylation site in NTPDase3.	Nitrogen	93-94	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	117-125
1919442-7	1991	Bacteria similarly initiate protein synthesis with N-formylmethionine; indeed, we established that Hmt can also present prokaryotic peptides in an N-formyl-dependent manner.	Nitrogen	51-52	histocompatibility 2, M region locus 3	Mus musculus	99-102
12686999-3	2003	Here we provide evidence for bacteria that anaerobically oxidize ammonium with nitrite to N2 in the world"s largest anoxic basin, the Black Sea.	Nitrogen	90-92	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	140-143
1654516-6	1991	The spin density of the unpaired electron in the NTP-adduct was centered on the nitrogen derived from its nitroso group.	Nitrogen	80-88	spindlin 1	Rattus norvegicus	4-8
12639906-8	2003	Western blot analyses using a Duox2-specific antipeptide showed that Duox2 has two N-glycosylation states, which have oligosaccharide motifs accounting for about 15 kDa and 25 kDa, respectively, of the apparent molecular mass.	Nitrogen	83-84	dual oxidase 2	Sus scrofa	69-74
1822994-5	1991	Also, a lipoxygenase cDNA coding region was able to detect changes in an mRNA that closely parallel changes in vsp94 protein levels resulting from alteration of nitrogen sinks.	Nitrogen	161-169	linoleate 9S-lipoxygenase-4	Glycine max	8-20
1822994-5	1991	Also, a lipoxygenase cDNA coding region was able to detect changes in an mRNA that closely parallel changes in vsp94 protein levels resulting from alteration of nitrogen sinks.	Nitrogen	161-169	linoleate 9S-lipoxygenase-4	Glycine max	111-116
12626414-5	2003	Here, employing transfection experiments with a series of glycoprotein acceptors, we report that this sulfotransferase has a marked preference for sulfating O-linked sugars of mucin-type acceptors, whereas other sulfotransferases in the family (GlcNAc6ST-1, GlcNAc6ST-2) and a Gal-6-O-sulfotransferase exhibit strong activity on both mucin-type acceptors and glycoproteins with predominantly N-linked chains.	Nitrogen	248-249	carbohydrate sulfotransferase 4	Homo sapiens	258-269
1660215-8	1991	Some 31 of the 33 cysteine residues and 17 of the 21 potential N-linked glycosylation sites of the FIV34TF10 env gene product were conserved among all five isolates.	Nitrogen	63-64	endogenous retrovirus group K member 20	Homo sapiens	109-112
12543137-7	2003	A set of new nitrogen and oxygen-specific descriptors were developed especially for this data set to better encode structural features, which are believed to directly influence DHFR inhibition and selectivity.	Nitrogen	13-21	dihydrofolate reductase	Homo sapiens	177-181
1872891-5	1991	On the contrary, N-acetylation paralleled with a decrease in the inhibition capacity: 55 microM N-acetyl putrescine, N-acetyl serotonin or N-omega-acetylhistamine suppressed ODC induction by ornithine in 66, 64 and 19%, respectively.	Nitrogen	17-18	ornithine decarboxylase, structural 1	Mus musculus	174-177
12637241-18	2003	Correlation analysis suggested that CYP2B11 catalyses the N-demethylation of dextromethorphan (mediated in humans by CYP3A) and the 4"-hydroxylation of mephenytoin (mediated in humans by CYP2C19) in the dog, and that this enzyme and CYP3A12 contribute to S-warfarin 7-hydroxylation (mediated in humans by CYP2C9).	Nitrogen	58-59	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	305-311
1868851-7	1991	In those cases where no other significant interaction but aromatic-ring stacking in the self-association process occurs, the release of protons from protonated nitrogen-ring sites is facilitated with increasing stacking; this holds not only for D2(GTP)2- as indicated above, but also for D2(ITP)2-, D(Ino)+, and D(Ado)+.	Nitrogen	160-168	immunoglobulin heavy diversity 2-15	Homo sapiens	245-253
12827869-2	2003	The results showed that in S-deficient solution, root vigor and leaf nitrate reductase (NR) activity significantly rdduced, top root ratio (T/R) increased, and S and N accumulation in tops and roots decreased.	Nitrogen	88-89	nitrate reductase [NADH] 1	Zea mays	69-86
1906892-7	1991	Compared with common-type TBG, the mutated polypeptide results in 1) 22 different amino acids on its carboxy-terminus, 2) a 22-amino acid truncation, and 3) the absence of a potential N-linked glycosylation site.	Nitrogen	184-185	serpin family A member 7	Homo sapiens	26-29
12505154-0	2003	Functional role of N-linked glycosylation on the rat melanin-concentrating hormone receptor 1.	Nitrogen	19-20	melanin-concentrating hormone receptor 1	Rattus norvegicus	53-93
1906977-5	1991	Upon treatment with endoglycosidase H, the 4-HBP UDPGT underwent about a 2000-dalton decrease in subunit molecular weight, suggesting that this protein is N-glycosylated.	Nitrogen	155-156	UDP glycosyltransferase 2 family, polypeptide B	Rattus norvegicus	49-54
12505154-2	2003	MCHR1 has three potential sites (Asn13, Asn16 and Asn23) for N-linked glycosylation in its extracellular amino-terminus which may modulate its reactivity.	Nitrogen	61-62	melanin-concentrating hormone receptor 1	Rattus norvegicus	0-5
12505154-4	2003	It was found that all three potential N-linked glycosylation sites in MCHR1 were glycosylated, and that N-linked glycosylation of Asn23 was necessary for full activity.	Nitrogen	38-39	melanin-concentrating hormone receptor 1	Rattus norvegicus	70-75
12505154-4	2003	It was found that all three potential N-linked glycosylation sites in MCHR1 were glycosylated, and that N-linked glycosylation of Asn23 was necessary for full activity.	Nitrogen	104-105	melanin-concentrating hormone receptor 1	Rattus norvegicus	70-75
1675157-5	1991	Mutations at two sites in the third domain that destroy consensus sequences for N-linked glycosylation enhance binding to purified Mac-1.	Nitrogen	80-81	integrin subunit alpha M	Homo sapiens	131-136
12505154-6	2003	These data outline the importance of the N-linked glycosylation of the MCHR1.	Nitrogen	41-42	melanin-concentrating hormone receptor 1	Rattus norvegicus	71-76
12613877-0	2003	Reassessment of biases in predicted nitrogen flows to the duodenum by NRC 2001.	Nitrogen	36-44	nuclear receptor coactivator 6	Homo sapiens	70-73
1903654-8	1991	Of the six potential N-glycosylation sites, four are located in conserved positions compared to human TBG.	Nitrogen	21-22	serpin family A member 7	Homo sapiens	102-105
12619892-1	2003	Beta 1,4 galactosyltransferase 1 (beta 1,4GT1) synthesizes Gal beta 1--&gt;4GlcNAc groups in N-linked sugar chains of animal glycoproteins, which have been demonstrated to play an important role in many biological events, including sperm-egg interaction, cell migration and mammalian embryonic development.	Nitrogen	79-80	beta-1,4-galactosyltransferase 1	Homo sapiens	0-32
1901219-2	1991	Analysis of the plasma enzyme indicated that almost all of the large carbohydrate moiety of LCAT (approximately 25% w/w) was N-linked with part of the high-mannose and part of the complex type.	Nitrogen	125-126	lecithin-cholesterol acyltransferase	Homo sapiens	92-96
2060596-5	1991	The linkage of an indole ring to a basic nitrogen atom via the 4 position on the indole ring or the absence of an indole ring are two features which lower the affinity for the 5-HT1D receptor, but do not necessarily lower the affinity for the 5-HT1A receptor.	Nitrogen	41-49	5-hydroxytryptamine receptor 1D	Homo sapiens	176-182
12619892-1	2003	Beta 1,4 galactosyltransferase 1 (beta 1,4GT1) synthesizes Gal beta 1--&gt;4GlcNAc groups in N-linked sugar chains of animal glycoproteins, which have been demonstrated to play an important role in many biological events, including sperm-egg interaction, cell migration and mammalian embryonic development.	Nitrogen	79-80	beta-1,4-galactosyltransferase 1	Homo sapiens	34-45
1987856-8	1991	Motilin enhanced gastric emptying to a similar degree as erythromycin, with a 2-hour gastric retention of 37% +/- 4% (NS).	Nitrogen	118-120	motilin	Canis lupus familiaris	0-7
16228377-5	2003	High CO(2) aggravates nitrogen limitations and in doing so may favor C(4) species, which have greater photosynthetic nitrogen use efficiency.	Nitrogen	117-125	complement C4A (Rodgers blood group)	Homo sapiens	69-73
1703489-4	1991	The polypeptide chain deduced from the AGA cDNA consists of 346 amino acids, has two potential N-glycosylation sites and 11 cysteine residues.	Nitrogen	45-46	aspartylglucosaminidase	Homo sapiens	39-42
1987650-3	1991	Administration of either APAP or PAP to mice resulted in significant elevations of plasma urea nitrogen and marked proximal tubular necrosis at 12 hr after dosing.	Nitrogen	95-103	poly (A) polymerase alpha	Mus musculus	26-29
16228377-8	2003	Eutrophication of soils by nitrogen deposition generally favors C(3) species by offsetting the superior nitrogen use efficiency of C(4) species; this should allow C(3) species to expand at the expense of C(4) plants.	Nitrogen	27-35	complement C4A (Rodgers blood group)	Homo sapiens	204-208
1987650-7	1991	Since the antibody used has been characterized as being directed primarily against the N-acetyl moiety of bound APAP metabolite and since it did not react with kidney proteins of mice given a nephrotoxic dose of PAP, it is unlikely that APAP deacetylation preceded binding or that acetylation of bound PAP occurred.	Nitrogen	87-88	poly (A) polymerase alpha	Mus musculus	113-116
16228377-8	2003	Eutrophication of soils by nitrogen deposition generally favors C(3) species by offsetting the superior nitrogen use efficiency of C(4) species; this should allow C(3) species to expand at the expense of C(4) plants.	Nitrogen	104-112	complement C4A (Rodgers blood group)	Homo sapiens	131-135
12519694-13	2003	N-acetylation of SeCys conjugates consistently increased the inhibitory potency towards CYP1A2, -2C19, -2E1 and -3A4.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	88-94
2243109-1	1990	The small keratan sulfate-substituted proteoglycan (fibromodulin) from articular cartilage was shown to contain keratan sulfate linked to the core protein through N-glycosidic linkages to residues Asn-109, Asn-147, Asn-182, and Asn-272.	Nitrogen	163-164	fibromodulin	Bos taurus	52-64
2089394-0	1990	New N-substituted derivatives of E-2"- and E-3"-hydroxystilbazoles-(4) of potential antimicrobial activity.	Nitrogen	0-1	cystatin 12, pseudogene	Homo sapiens	33-36
12438625-5	2002	We found that VLP bound to sialoglycoproteins, including alpha1-acid glycoprotein, fetuin, and transferrin receptor, and that this binding depended on alpha2-3-linked sialic acids and N-linked sugar chains.	Nitrogen	184-185	VHL like	Homo sapiens	14-17
2141043-0	1990	Fc gamma RIII expressed on cultured monocytes is a N-glycosylated transmembrane protein distinct from Fc gamma RIII expressed on natural killer cells.	Nitrogen	51-52	Fc gamma receptor IIIa	Homo sapiens	0-13
12218058-2	2002	Sequence analysis suggests that BMP-1 has six potential N-linked glycosylation sites (i.e. NXS/T) namely: Asn(91) (prodomain), Asn(142) (metalloproteinase domain), Asn(332) and Asn(363) (CUB1 domain), Asn(599) (CUB3 domain), and Asn(726) in the C-terminal-specific domain.	Nitrogen	56-57	bone morphogenetic protein 1	Homo sapiens	32-37
2173521-4	1990	Total N intake was 117, 185, 187, 174 and 172 g/d, and duodenal N flow was 121, 148, 143, 162 and 169 g/d for B, S, SF, CB and CBF, respectively, being lower for B than for other treatments and higher for supplements with the corn gluten and blood meal mix than for soybean meal (P less than 0.05).	Nitrogen	64-65	CRT binding factor 1	Glycine max	127-130
2173521-5	1990	Duodenal microbial N flow was 39, 51, 49, 38 and 45 g/d for B, S, SF, CB and CBF, respectively, being greater (P less than 0.05) for supplements with soybean meal than with corn gluten and blood meals.	Nitrogen	19-20	CRT binding factor 1	Glycine max	77-80
12421307-10	2002	Biochemical analyses showed that epitope-tagged Dcw1p is an N-glycosylated, GPI-anchored membrane protein and is localized in the membrane fraction including the cell surface.	Nitrogen	60-61	putative mannan endo-1,6-alpha-mannosidase	Saccharomyces cerevisiae S288C	48-53
2332381-0	1990	Effect of exogenous porcine somatotropin administration on nitrogen and energy metabolism in three genotypes of pigs.	Nitrogen	59-67	somatotropin	Sus scrofa	28-40
12491790-6	2002	A decreased rate of SSAO inhibition under N2 atmosphere to that obtained under O2 was produced after 2-BEA treatment, suggesting that oxidised intermediate was necessary for its inhibition.	Nitrogen	42-44	amine oxidase copper containing 2	Homo sapiens	20-24
2157039-3	1990	Consistent with endoplasmic reticulum and nuclear membrane localization, the bulk of gp110 was sensitive to endoglycosidase H, indicating high-mannose, pre-Golgi, N-linked glycosylation; while consistent with Golgi and plasma membrane localization, gp350/220 was mostly resistant to endoglycosidase H because of complex N- and O-linked glycosylation.	Nitrogen	163-164	CD68 molecule	Homo sapiens	85-90
2157039-3	1990	Consistent with endoplasmic reticulum and nuclear membrane localization, the bulk of gp110 was sensitive to endoglycosidase H, indicating high-mannose, pre-Golgi, N-linked glycosylation; while consistent with Golgi and plasma membrane localization, gp350/220 was mostly resistant to endoglycosidase H because of complex N- and O-linked glycosylation.	Nitrogen	320-321	CD68 molecule	Homo sapiens	85-90
12140287-2	2002	During nitrogen starvation or growth in medium containing a poor nitrogen source, Gln3 is nuclear and NCR-sensitive transcription is high.	Nitrogen	7-15	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	82-86
1689184-4	1990	Binding studies with horseradish peroxidase-labelled lectins indicated that all the vitronectins contained complex-type, sialylated N-linked sugar chains and that only porcine vitronectin had a fucosylated sugar chain.	Nitrogen	132-133	vitronectin	Homo sapiens	84-95
12140287-2	2002	During nitrogen starvation or growth in medium containing a poor nitrogen source, Gln3 is nuclear and NCR-sensitive transcription is high.	Nitrogen	65-73	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	82-86
12140287-3	2002	However, when cells are grown in excess nitrogen, Gln3 is localized to the cytoplasm with a concomitant decrease in gene expression.	Nitrogen	40-48	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	50-54
2152894-1	1990	Diploid yeast cells that carry a part of the CYR1 gene deficient in a region coding for the N-terminal domain of adenylate cyclase were growth arrested and accumulated unbudded cells after inoculation into complete medium or nitrogen-free medium, but produced many cells which had one or more buds after incubation in sporulation medium.	Nitrogen	225-233	adenylate cyclase	Saccharomyces cerevisiae S288C	45-49
2152894-1	1990	Diploid yeast cells that carry a part of the CYR1 gene deficient in a region coding for the N-terminal domain of adenylate cyclase were growth arrested and accumulated unbudded cells after inoculation into complete medium or nitrogen-free medium, but produced many cells which had one or more buds after incubation in sporulation medium.	Nitrogen	225-233	adenylate cyclase	Saccharomyces cerevisiae S288C	113-130
12140287-6	2002	Here we show that nuclear localization of Gln3 during carbon starvation derives from its indirect effects on nitrogen metabolism, i.e. Gln3 does not move into the nucleus of carbon-starved cells if glutamine rather than ammonia is provided as the nitrogen source.	Nitrogen	109-117	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
12140287-6	2002	Here we show that nuclear localization of Gln3 during carbon starvation derives from its indirect effects on nitrogen metabolism, i.e. Gln3 does not move into the nucleus of carbon-starved cells if glutamine rather than ammonia is provided as the nitrogen source.	Nitrogen	247-255	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	42-46
12382055-8	2002	Phenotype analysis showed that the moeA gene is required for A. mediterranei growth in a minimal medium with nitrate as sole nitrogen source, possibly because nitrate reductase activity is diminished due to disruption of the moeA gene.	Nitrogen	125-133	molybdopterin molybdotransferase MoeA	Amycolatopsis mediterranei U32	35-39
33811408-4	2021	This review summarizes the current knowledge about 14-3-3 proteins in plants, including their molecular structure and function, regulatory mechanism, and roles in carbon and nitrogen metabolism and stress responses.	Nitrogen	174-182	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta	Homo sapiens	51-57
12382055-10	2002	The results demonstrate that the moeA gene is necessary for rifamycin SV production in A. mediterranei, and that the nitrogen assimilation pathway involved in nitrate reductase is the major pathway for the genesis of the amide nitrogen atom in the rifamycin SV molecule.	Nitrogen	227-235	molybdopterin molybdotransferase MoeA	Amycolatopsis mediterranei U32	33-37
33801062-1	2021	In this paper, we have demonstrated the optimized device performance in the Gamma-shaped gate AlGaN/AlN/GaN metal oxide semiconductor high electron mobility transistor (MOS-HEMT) by incorporating aluminum into atomic layer deposited (ALD) HfO2 and comparing it with the commonly used HfO2 gate dielectric with the N2 surface plasma treatment.	Nitrogen	314-316	MOS proto-oncogene, serine/threonine kinase	Homo sapiens	169-172
12208554-7	2002	In summary, it is proposed that N-demethylation of the mentioned phenothiazine neuroleptics in the rat is catalyzed by the isoenzymes CYP2D1, CYP2B2 and CYP1A2 (CYP1A2 does not refer to promazine).	Nitrogen	32-33	cytochrome P450, family 2, subfamily b, polypeptide 2	Rattus norvegicus	142-148
33801062-6	2021	Moreover, IG was reduced more than one order of magnitude in HfAlOX MOS-HEMT by the N2 surface plasma treatment, due to reduction of N2 vacancies which were created by ICP dry etching.	Nitrogen	84-86	MOS proto-oncogene, serine/threonine kinase	Homo sapiens	68-71
12167564-7	2002	None of the UGTs examined catalyzed the N-glucuronidation of S(-)-nicotine, R(+)-nicotine, and S(-)-cotinine, including UGT1A3 and UGT1A4, the only isoforms known to catalyze many substrates at a tertiary amine.	Nitrogen	0-1	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	131-137
33033175-3	2020	Coupling this MAOB-sensitive group to a nitrogen mustard produced a prodrug that damaged GBM mitochondria and killed GBM cells.	Nitrogen	40-48	monoamine oxidase B	Homo sapiens	14-18
12362463-7	2002	Urinary N as a percentage of digested N, and total N excretion expressed relative to milk N were lower for the alpha S1-CN A/A goats than for the alpha S1-CN F/F goats.	Nitrogen	8-9	alpha-S1-casein	Capra hircus	111-122
12741822-4	2003	In each polypeptide chain, the free alpha-amino nitrogen and carbonyl oxygen of the amino-terminal Ser residue coordinate to a Zn(2+) ion to form a five-membered chelate, and the syn-unidentate interaction of the Asp7 side chain with the Zn(2+) cation leads to the formation of a unique docking arrangement for helix capping.	Nitrogen	48-56	synemin	Homo sapiens	179-182
11983532-3	2002	The functionality attached to the piperidine nitrogen was varied extensively to determine the SAR for this series.	Nitrogen	45-53	sarcosinemia autosomal recessive	Mus musculus	94-97
9714758-6	1998	Using beta-lactamase as a reporter, we show that the FLD1 promoter (PFLD1) is strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source).	Nitrogen	180-188	seipin	Saccharomyces cerevisiae S288C	53-57
9714758-6	1998	Using beta-lactamase as a reporter, we show that the FLD1 promoter (PFLD1) is strongly and independently induced by either methanol as sole carbon source (with ammonium sulfate as nitrogen source) or methylamine as sole nitrogen source (with glucose as carbon source).	Nitrogen	220-228	seipin	Saccharomyces cerevisiae S288C	53-57
12180536-4	2002	Furafylline (CYP1A2) and sulfaphenazole (CYP2C9) inhibited the N-demethylation to a lesser extent while quinidine (CYP2D6) or troleandomycine (CYP3A4) had no effect.	Nitrogen	63-64	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	13-19
34848359-11	2022	The results showed that DWPE could decline the concentration of ammonia and increase the expressions of carbonic anhydrase 2 (CA2) and carbamoylphosphate synthetase (CPS1) in nitrogen metabolism.	Nitrogen	175-183	carbamoyl-phosphate synthase 1	Rattus norvegicus	166-170
12180536-4	2002	Furafylline (CYP1A2) and sulfaphenazole (CYP2C9) inhibited the N-demethylation to a lesser extent while quinidine (CYP2D6) or troleandomycine (CYP3A4) had no effect.	Nitrogen	63-64	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	41-47
11901144-3	2002	Polycystin-1 is heavily N-glycosylated, and several glycosylated forms of polycystin-1 differing in their sensitivity to endoglycosidase H (Endo H) were found; in contrast, native polycystin-2 was fully Endo H-sensitive.	Nitrogen	24-25	polycystin 1, transient receptor potential channel interacting	Homo sapiens	0-12
34793904-4	2022	This Article describes the physical and chemical transformations of NAg as well as the impact of the nanoparticle on microbial communities in different environmental settings; how the nanoparticle shifts not only the diversity and abundance of microbes, including those that are important in nitrogen cycles and decomposition of organic matters, but also their associated genes and in turn, the key metabolic processes.	Nitrogen	292-300	NBAS subunit of NRZ tethering complex	Homo sapiens	68-71
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	allantoate permease	Saccharomyces cerevisiae S288C	110-114
34937426-12	2022	Immunoblot studies on lysates of transfected cells cultured in absence or presence of tunicamycin indicated that SLC17A4 is subject to N-linked glycosylation.	Nitrogen	135-136	solute carrier family 17 member 4	Homo sapiens	113-120
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	243-248
34784297-4	2021	Cellular analyses of cartilage defects in pmm2 sa10150 embryos revealed a block in chondrogenesis that is associated with defective proteolytic processing, but seemingly normal N-glycosylation, of the cell adhesion molecule N-cadherin.	Nitrogen	177-178	cadherin 2	Homo sapiens	224-234
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	Rtg3p	Saccharomyces cerevisiae S288C	274-279
12162998-2	2002	Whereas IGFBP-1 and IGFBP-2 are not glycosylated, IGFBP-3 and IGFBP-4 are N-glycosylated and IGFBP-5 and IGFBP-6 are O-glycosylated.	Nitrogen	74-75	insulin-like growth factor binding protein 3	Rattus norvegicus	50-57
34710380-3	2021	N-glycosylation at Fc portion can regulate these mechanisms and many experimental evidences suggest that modifications of glycosidic chains can affect the antibody binding to FcgammaRIIIa, consequently impacting the immune response.	Nitrogen	0-1	Fc gamma receptor IIIa	Homo sapiens	175-187
34812814-5	2021	(GeF4{o-C6H4(PMe2)2}), containing the cis-chelating diphosphine, also reacts with n equivalents of TMSOTf to generate (GeF4-n{o-C6H4(PMe2)2}(OTf)n) (n = 1, 2, 3).	Nitrogen	82-83	Rho guanine nucleotide exchange factor 4	Homo sapiens	1-5
34812814-5	2021	(GeF4{o-C6H4(PMe2)2}), containing the cis-chelating diphosphine, also reacts with n equivalents of TMSOTf to generate (GeF4-n{o-C6H4(PMe2)2}(OTf)n) (n = 1, 2, 3).	Nitrogen	82-83	Rho guanine nucleotide exchange factor 4	Homo sapiens	119-123
34861885-0	2021	ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism.	Nitrogen	76-84	argininosuccinate lyase	Homo sapiens	9-12
12068081-1	2002	Soluble N -ethylmaleimide-sensitive factor attachment protein receptors (SNAREs), including synaptosome-associated proteins of 25 kDa (SNAP25), syntaxins, and vesicle-associated membrane proteins (VAMP), are essential for regulated exocytosis of synaptic vesicles in neurotransmission.	Nitrogen	8-9	synaptosome associated protein 25	Homo sapiens	92-133
34863624-1	2021	Phosphomannomutase 2 deficiency, PMM2-CDG, is the most frequent disorder of protein N-glycosylation.	Nitrogen	84-85	phosphomannomutase 2	Homo sapiens	0-20
34863624-1	2021	Phosphomannomutase 2 deficiency, PMM2-CDG, is the most frequent disorder of protein N-glycosylation.	Nitrogen	84-85	phosphomannomutase 2	Homo sapiens	33-37
34813810-2	2022	To quantify these reactive N emissions the Nitrogen Footprint (NF) can serve as a valuable indicator.	Nitrogen	27-28	neurofascin	Homo sapiens	43-61
34813810-2	2022	To quantify these reactive N emissions the Nitrogen Footprint (NF) can serve as a valuable indicator.	Nitrogen	27-28	neurofascin	Homo sapiens	63-65
34813810-5	2022	The total NF of the research center INIA for 2019 was 9289 kg N and its NF per capita is 16.1 kg N per full-time equivalent population.	Nitrogen	62-63	neurofascin	Homo sapiens	10-12
34813810-5	2022	The total NF of the research center INIA for 2019 was 9289 kg N and its NF per capita is 16.1 kg N per full-time equivalent population.	Nitrogen	62-63	neurofascin	Homo sapiens	72-74
34813810-5	2022	The total NF of the research center INIA for 2019 was 9289 kg N and its NF per capita is 16.1 kg N per full-time equivalent population.	Nitrogen	97-98	neurofascin	Homo sapiens	10-12
34813810-5	2022	The total NF of the research center INIA for 2019 was 9289 kg N and its NF per capita is 16.1 kg N per full-time equivalent population.	Nitrogen	97-98	neurofascin	Homo sapiens	72-74
34813810-7	2022	Taking the NF of INIA as baseline the following strategies of N mitigation were analyzed: (1) beef replacement in the menu, (2) reduction of meat by non-meat sources, (3) reduction of beef, fish, and seafood by other protein sources, (4) improving the wastewater treatment efficiency, and (5) recycling food waste.	Nitrogen	62-63	neurofascin	Homo sapiens	11-13
34813810-8	2022	This institutional NF approach serves INIA"s institution as an indicator to quantify its N pollution and allows the identification of useful mitigation strategies to reduce the overall NF.	Nitrogen	89-90	neurofascin	Homo sapiens	19-21
34787535-1	2022	Cryopreserving tissues for histology requires the use of coolants to buffer the sample from liquid nitrogen (LN2) and to control the rate of temperature decline.	Nitrogen	99-107	NZ lupus nephritis 2	Mus musculus	109-112
34420225-2	2021	These sigma-complexes originate from the unique combination of 12 stannylenes (SnX2 ) with five azabenzene ligands (pyridine, pyrazine, pyrimidine, pyridazine, and s-triazine), where the nitrogen center of the ligand acts as sigma-donor and the tin(II) center as sigma-acceptor in a 1:1 fashion.	Nitrogen	187-195	sorting nexin 2	Homo sapiens	79-83
34741275-3	2021	Introducing an additional N-atom into the heterocyclic ring system was tolerable for rA1 AR affinity and also led to rA2A AR affinity.	Nitrogen	26-27	UDP glucuronosyltransferase family 1 member A6	Rattus norvegicus	85-88
34831215-16	2021	CONCLUSION: The allocation of FLT3-ITD to different cellular compartments and targeting distinct downstream signaling pathways by combined treatment with N-glycosylation and HSP90 inhibitors or VPA and rapamycin might represent new therapeutic strategies to overcome resistance towards tyrosine kinase inhibitors in FLT3-ITD-positive AML.	Nitrogen	154-155	FMS-like tyrosine kinase 3	Mus musculus	30-34
34831215-17	2021	The treatment approaches addressing N-glycosylation of FLT3-ITD appear to depend on patient-specific FLT3-ITD sequences, potentially affecting the efficacy of such pharmacological strategies.	Nitrogen	36-37	FMS-like tyrosine kinase 3	Mus musculus	55-59
34831215-17	2021	The treatment approaches addressing N-glycosylation of FLT3-ITD appear to depend on patient-specific FLT3-ITD sequences, potentially affecting the efficacy of such pharmacological strategies.	Nitrogen	36-37	FMS-like tyrosine kinase 3	Mus musculus	101-105
34464010-2	2021	Monoterpenes like alpha-pinene (ALP) is considered to be a therapeutically potent antioxidant agent able to attenuate and scavenge various reactive oxygen species and reactive nitrogen species.	Nitrogen	176-184	PDZ and LIM domain 3	Rattus norvegicus	32-35
34649176-5	2021	Even modest values of J are large relative to the separation between trityl and nitroxide resonances for some nitrogen nuclear spin state.	Nitrogen	110-118	spindlin 1	Homo sapiens	127-131
34769188-5	2021	P5C has a cyclic structure containing a tertiary nitrogen atom (N) and is in tautomeric equilibrium with the open-chain form of L-glutamate-gamma-semialdehyde (GSAL).	Nitrogen	49-57	pyrroline-5-carboxylate reductase 1	Homo sapiens	0-3
34495561-2	2021	The electrophilic activation of B-H bonds in the carborane moiety gives rise to a proton transfer from boron to nitrogen at slightly elevated temperatures, as rationalized by the isolation of a mixture of the zwitterionic isomers 12- and 7-(2-(tBuN{H}CH)C6H4Te(CB11H11)) in ratios ranging from 62:38 to 80:20.	Nitrogen	112-120	bleomycin hydrolase	Homo sapiens	32-35
34648192-5	2022	RESULTS: The experiments in supersomes revealed CYP1A2 as the major CYP for 4-MAA N-demethylation and 4-FAA formation with CYP2C19 and CYP2D6 contributing to N-demethylation.	Nitrogen	158-159	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	123-130
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	77-85	carbonic anhydrase 4	Ovis aries	49-52
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	77-85	carbonic anhydrase 9	Ovis aries	54-57
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	77-85	carbonic anhydrase 12	Ovis aries	59-63
34607533-7	2021	Noteworthy, the expression levels of most genes (CA4, CA9, CA12 and CA14) in nitrogen metabolic pathways were negatively correlated with the papilla length and width, but the papilla length and width were positively correlated with the expression of genes (PLA2G3, SLC26A9, SLC34A3) in ion transport pathway, suggesting that these genes may be involved in nitrogen metabolic and ion transport pathway and thus affect rumen development.	Nitrogen	356-364	carbonic anhydrase 4	Ovis aries	49-52
34127537-6	2021	Methods: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we employed liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 IgAN patients and 244 age and sex-matched healthy controls.	Nitrogen	50-51	immunoglobulin heavy constant alpha 1	Homo sapiens	75-79
34127537-7	2021	Results: Multiple structural features of N-glycosylation of IgA1 and IgA2 were associated with IgAN and glomerular function in our cross-sectional study.	Nitrogen	41-42	immunoglobulin heavy constant alpha 1	Homo sapiens	60-64
34352515-5	2021	Compared with those incubated with NH4+, juice sacs under nitrogen deficiency exhibited enhanced flux through phosphoenolpyruvate carboxykinase (PEPCK) and accelerated consumption of citrate, while the other two TCA cycle efflux points, through malic enzyme (ME) and glutamate dehydrogenase (GDH), were both repressed.	Nitrogen	58-66	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	110-143
34352515-5	2021	Compared with those incubated with NH4+, juice sacs under nitrogen deficiency exhibited enhanced flux through phosphoenolpyruvate carboxykinase (PEPCK) and accelerated consumption of citrate, while the other two TCA cycle efflux points, through malic enzyme (ME) and glutamate dehydrogenase (GDH), were both repressed.	Nitrogen	58-66	phosphoenolpyruvate carboxykinase 2, mitochondrial	Homo sapiens	145-150
34455356-0	2021	N130, N175 and N207 are N-linked glycosylation sites of duck Tembusu virus NS1 that are important for viral multiplication, viremia and virulence in ducklings.	Nitrogen	24-25	influenza virus NS1A binding protein	Homo sapiens	75-78
34455356-2	2021	DTMUV nonstructural protein 1 (NS1) contains three potential predicted N-linked glycosylation sites at residues 130, 175 and 207.	Nitrogen	71-72	influenza virus NS1A binding protein	Homo sapiens	31-34
34455356-10	2021	Overall, our results indicated that N130, N175 and N207 are N-linked glycosylation sites of DTMUV NS1, which play crucial roles in viral multiplication, viremia and virulence in vitro and in vivo.	Nitrogen	60-61	influenza virus NS1A binding protein	Homo sapiens	98-101
34502536-4	2021	Long-term exposure to TiO2 nanoparticles co-doped with 1% of iron and nitrogen led to the alteration of p53 protein activity and the gene expression controlled by this suppressor (NF-kB and mdm2), DNA damage, cell cycle disruptions at the G2/M and S phases, and lysosomal membrane permeabilization and the subsequent release of cathepsin B, triggering the intrinsic pathway of apoptosis in a Bax- and p53-independent manner.	Nitrogen	70-78	MDM2 proto-oncogene	Homo sapiens	190-194
34502536-4	2021	Long-term exposure to TiO2 nanoparticles co-doped with 1% of iron and nitrogen led to the alteration of p53 protein activity and the gene expression controlled by this suppressor (NF-kB and mdm2), DNA damage, cell cycle disruptions at the G2/M and S phases, and lysosomal membrane permeabilization and the subsequent release of cathepsin B, triggering the intrinsic pathway of apoptosis in a Bax- and p53-independent manner.	Nitrogen	70-78	cathepsin B	Homo sapiens	328-339
34432475-0	2021	Regulating Electronic Spin Moments of Single-Atom Catalyst Sites via Single-Atom Promoter Tuning on S-Vacancy MoS2 for Efficient Nitrogen Fixation.	Nitrogen	129-137	spindlin 1	Homo sapiens	22-26
34432475-3	2021	Using first-principles calculations, we first report the crucial role of the spin of exposed Mo atoms around an S-vacancy in the electrocatalytic dinitrogen reduction reaction on defective MoS2 nanosheets and propose a novel strategy for regulating the electronic spin moments by tuning a single-atom promoter (SAP).	Nitrogen	146-156	spindlin 1	Homo sapiens	77-81
34432475-3	2021	Using first-principles calculations, we first report the crucial role of the spin of exposed Mo atoms around an S-vacancy in the electrocatalytic dinitrogen reduction reaction on defective MoS2 nanosheets and propose a novel strategy for regulating the electronic spin moments by tuning a single-atom promoter (SAP).	Nitrogen	146-156	spindlin 1	Homo sapiens	264-268
34432475-4	2021	Single TM atoms adsorbed on a defective MoS2 basal plane serve as SAPs via a noncontact interaction with an exposed Mo active site, inducing a significant spin polarization that promotes N2 adsorption and activation.	Nitrogen	187-189	spindlin 1	Homo sapiens	155-159
34432475-6	2021	The spin moments can be tuned to largely improve the catalytic activity of MoS2 toward the reduction of N2 to NH3.	Nitrogen	104-106	spindlin 1	Homo sapiens	4-8
34115149-8	2021	Ammonia losses were estimated as 24.2% and 7.43% of the total N applied in P1 and P2, respectively.	Nitrogen	62-63	crystallin gamma F, pseudogene	Homo sapiens	75-84
34282273-12	2021	Additionally, the mutation of CD44 with six N-glycosylation sites showed less sensibility to NEU4 on cell migration compared with wild-type CD44.	Nitrogen	44-45	CD44 antigen	Mus musculus	30-34
34513728-5	2021	Furthermore, when the M-N interaction was disrupted via certain rationally designed peptides, the PDK1-PKB/Akt signaling was restored, and the boosting activity of N on the M-triggered apoptosis was abolished.	Nitrogen	24-25	pyruvate dehydrogenase kinase 1	Homo sapiens	98-102
34214466-5	2021	The structures reveal that ZYG11B and ZER1 utilize their armadillo (ARM) repeats forming a deep and narrow cavity to engage mainly the first four residues of Gly/N-degrons.	Nitrogen	162-163	zyg-11 family member B, cell cycle regulator	Homo sapiens	27-33
34489931-12	2021	FHR1 and FHR5 binding was primarily mediated by N-sulfation while FH binding depended on N-, 2-O- and 6-O-sulfation.	Nitrogen	48-49	complement factor H related 5	Homo sapiens	9-13
34180718-9	2021	Intravenous transfusion of renal NG2+ cells isolated from donor mice on day 3 after reperfusion into recipient mice on day 1 after I/R surgery revealed that NG2+ cell-injected mice had lower plasma blood urea nitrogen, reduced KIM-1 mRNA expression, ameliorated renal damage, and reduced cellular debris accumulation than PBS-injected mice on day 5 after reperfusion.	Nitrogen	209-217	chondroitin sulfate proteoglycan 4	Mus musculus	33-36
34180718-9	2021	Intravenous transfusion of renal NG2+ cells isolated from donor mice on day 3 after reperfusion into recipient mice on day 1 after I/R surgery revealed that NG2+ cell-injected mice had lower plasma blood urea nitrogen, reduced KIM-1 mRNA expression, ameliorated renal damage, and reduced cellular debris accumulation than PBS-injected mice on day 5 after reperfusion.	Nitrogen	209-217	chondroitin sulfate proteoglycan 4	Mus musculus	157-160
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	22-23	nitrite reductase 1	Arabidopsis thaliana	126-143
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	22-23	nitrite reductase 1	Arabidopsis thaliana	145-148
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	36-37	nitrite reductase 1	Arabidopsis thaliana	126-143
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	36-37	nitrite reductase 1	Arabidopsis thaliana	145-148
34260255-0	2021	Following Metal-to-Ligand Charge-Transfer Dynamics with Ligand and Spin Specificity Using Femtosecond Resonant Inelastic X-ray Scattering at the Nitrogen K-Edge.	Nitrogen	145-153	spindlin 1	Homo sapiens	67-71
34440053-6	2021	In contrast to the great number of studies conducted in adults, there are only limited data on the effects of n-3 PUFA supplementation in children and adolescents who suffer from mental disorders or show a high risk of developing psychiatric disorders.	Nitrogen	110-111	pumilio RNA binding family member 3	Homo sapiens	114-118
34125520-4	2021	In the related reaction of LnacnacY(PhNCH2PPh2)2 with (Ph3P)2PdI(Ph), the P-C bond cleavage following with a N-C bond formation was observed.	Nitrogen	109-110	relaxin 2	Homo sapiens	36-48
34109953-6	2021	Density functional theory calculations show that Co-N-Ni3S2/NF exhibits stronger water adsorption energy than those of N-Ni3S2/NF, Co-Ni3S2/NF and Ni3S2/NF.	Nitrogen	119-121	neurofascin	Homo sapiens	127-129
34109953-7	2021	It is proved that the doping of Co and N can effectively regulate the electron cloud density of Ni, thus enhancing the electrochemical activity of Co-N-Ni3S2/NF.	Nitrogen	39-40	neurofascin	Homo sapiens	152-160
34207447-6	2021	Thus, the objective of this study was to analyse the gene and protein expression of the enzymes NOX-1, NOX-2 and iNOS, which are involved in the production of reactive oxygen and nitrogen species, respectively.	Nitrogen	179-187	cytochrome b-245 beta chain	Homo sapiens	103-108
34145370-3	2021	Our results indicated the significantly higher values of soil C/N ratio in S2, S3, and S4 compared with that in CK.	Nitrogen	64-65	cytidine/uridine monophosphate kinase 1	Homo sapiens	112-114
34177326-11	2021	These results suggested the existence of metabolic regulation that coordinates biomass and N metabolism involving AtGLN2 in F1 hybrids.	Nitrogen	91-92	glutamine synthetase 2	Arabidopsis thaliana	114-120
12023522-4	2002	In rat hippocampal slices, prolonged low-frequency stimulation (LFS) of CA1 Schaffer collaterals (1 Hz for 7 min) induced saturable, long-lasting, reversible N-methyl-D-aspartate (NMDA) receptor-dependent LTD of stimulus-evoked dendritic population excitatory postsynaptic potentials.	Nitrogen	158-159	carbonic anhydrase 1	Rattus norvegicus	72-75
35593200-0	2022	Spin state engineering of spinel oxides by integration of Cr doping and a p-n junction for water oxidation.	Nitrogen	76-77	spindlin 1	Homo sapiens	0-4
12187646-11	2002	The supply of 8 t ha-1 of wheat residues at seeding time, and 15 or 30 d before seeding, decreased the dry matter yield and N accumulation in wheat crop.	Nitrogen	124-125	plasma membrane ATPase	Triticum aestivum	18-22
35182426-0	2022	Nitrogen deficiency- and sucrose-induced anthocyanin biosynthesis is modulated by HISTONE DEACETYLASE15 in Arabidopsis.	Nitrogen	0-8	histone deacetylase 15	Arabidopsis thaliana	82-103
12096925-3	2002	We found that interferon-gamma (IFN-gamma) treatment increased the presence of high molecular weight forms of CD95 in these cells as judged by Western analysis, and treatment of protein extracts with Peptide: N -glycosidase F indicated that the majority of high molecular weight forms were due to N-linked glycosylation.	Nitrogen	34-35	Fas cell surface death receptor	Homo sapiens	110-114
35569778-4	2022	In a model of LPS-induced inflammation, we found that hypoxia induced by infusing nitrogen into water increased the expression of pro-inflammatory cytokines, such as il-1beta, il-6, and il-8.	Nitrogen	82-90	interleukin 6 (interferon, beta 2)	Danio rerio	176-180
35569778-4	2022	In a model of LPS-induced inflammation, we found that hypoxia induced by infusing nitrogen into water increased the expression of pro-inflammatory cytokines, such as il-1beta, il-6, and il-8.	Nitrogen	82-90	chemokine (C-X-C motif) ligand 8a	Danio rerio	186-190
11912240-0	2002	The role of glutamine synthetase and glutamate dehydrogenase in nitrogen assimilation and possibilities for improvement in the nitrogen utilization of crops.	Nitrogen	64-72	glutamate dehydrogenase 1	Homo sapiens	37-60
35022995-2	2022	DynAP is a single-pass transmembrane protein with a carboxy-terminal region (amino acids 135-210) exposed to the outside of the cell possessing one potential N-glycosylation site (position 143) and a distal C-terminal region (residues 173-210) harboring a Thr/Ser-rich (T/S) cluster that may be O-glycosylated.	Nitrogen	158-159	dynactin associated protein	Mus musculus	0-5
11915731-9	2002	Our results indicate that it may be possible to predict lymphatic metastasis by determining the T/N ratio for OPRT before surgery.	Nitrogen	98-99	uridine monophosphate synthetase	Homo sapiens	110-114
12079123-1	2002	In Kattegat and the coastal water of the Baltic Sea, high nitrogen input from agricultural land is considered to be the main reason for eutrophication.	Nitrogen	58-66	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	48-51
35279841-4	2022	The plastidic glutamine synthetase (GS2) enzyme stands at the crossroads of N assimilation and photorespiration, and is therefore a key candidate for the improvement of crop performance.	Nitrogen	76-77	glutamine synthetase 2	Arabidopsis thaliana	36-39
11714605-3	2001	Substitution of the ethanolamine nitrogen with a benzyl group bearing a para hydrogen bond acceptor promoted beta(3) selectivity.	Nitrogen	33-41	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	109-116
35637269-9	2022	MALDI-TOF MS analysis of patient serum showed disorders of N-linked glycosylation, including increased N-glycans and elevated Man5/Man6 and Man5/Man9 value.	Nitrogen	59-60	mannosidase alpha class 1A member 1	Homo sapiens	145-149
35552412-3	2022	We initially observed altered leaf to seed ratios, faster senescence progression, altered leaf nitrogen recovery after transient nitrogen removal and ultimately enhanced nitrogen remobilization from the leaves in two methylation mutants (ros1 and the triple dmr1/2 cmt3 knockout).	Nitrogen	170-178	chromomethylase 3	Arabidopsis thaliana	265-269
11743740-5	2001	The nitrosating nitrogen oxide species N(2)O(3) is likely to be the disrupter of Ace1 activity.	Nitrogen	39-40	Cup2p	Saccharomyces cerevisiae S288C	81-85
35628140-5	2022	Using a unique transgenic mouse (FAT-1) model combined with dietary supplementation experiments, we demonstrate that an elevated tissue n-3 PUFA status with a decreased n-6/n-3 PUFA ratio significantly reduces CPT-11-induced weight loss, bloody diarrhea, gut pathological changes, and mortality.	Nitrogen	136-137	FAT atypical cadherin 1	Mus musculus	33-38
35150821-5	2022	Functional studies verified that the endocytosis-related genes CAP1 and END3 significantly increased the utilization of multiple non-preferred amino acids and reduced the accumulation of the harmful nitrogen metabolite precursor urea by regulating amino acid transporters and TOR pathway.	Nitrogen	199-207	Cap1p	Saccharomyces cerevisiae S288C	63-67
35150821-6	2022	The mitochondria-related gene ATP12, MRPL22, MRP1 and NAM9 significantly increased the utilization of multiple non-preferred amino acids and reduced accumulation of the urea by coordinately regulating nitrogen catabolism repression, Ssy1p-Ptr3p-Ssy5p signaling sensor system, amino acid transporters, TOR pathway and urea metabolism-related pathways.	Nitrogen	201-209	mitochondrial 54S ribosomal protein YmL22	Saccharomyces cerevisiae S288C	37-43
35150821-6	2022	The mitochondria-related gene ATP12, MRPL22, MRP1 and NAM9 significantly increased the utilization of multiple non-preferred amino acids and reduced accumulation of the urea by coordinately regulating nitrogen catabolism repression, Ssy1p-Ptr3p-Ssy5p signaling sensor system, amino acid transporters, TOR pathway and urea metabolism-related pathways.	Nitrogen	201-209	Ptr3p	Saccharomyces cerevisiae S288C	239-244
11747200-4	2001	The Oosp1 cDNA encodes a 202-amino acid protein that contains a 21-amino acid signal peptide sequence, 5 putative N-linked glycosylation consensus sequences, and 6 cysteines that are predicted to form 3 disulfide bonds.	Nitrogen	12-13	oocyte secreted protein 1	Mus musculus	4-9
35600875-3	2022	Nitrogen-containing bisphosphonates suppress osteoclastic resorption by inhibiting farnesyl pyrophosphate synthase in the mevalonate pathway, leading to deficiency of the substrate for GTPase prenylation.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	83-114
35499352-5	2022	N-glycosylation and the global and local selection pressure in the putative GP5 encoded by ORF5 were estimated.	Nitrogen	0-1	CWC15 spliceosome associated protein homolog	Homo sapiens	91-95
11451951-4	2001	The influence of the six individual potential N-glycosylation sites of human acid ceramidase on targeting, processing, and catalytic activity was determined by site-directed mutagenesis.	Nitrogen	46-47	N-acylsphingosine amidohydrolase 1	Homo sapiens	77-92
35277949-2	2022	Herein, a facile approach is utilized to prepare free-standing 3D cathode substrates comprising nitrogen-doped carbon (N-C) scaffold and metal-organic framework derived interconnected chain-like hollow N-C nanocages, forming a highly porous N-C nanofiber (HP-N-CNF) framework.	Nitrogen	96-104	NPHS1 adhesion molecule, nephrin	Homo sapiens	261-264
35499203-3	2022	Herein, to cope with this issue, through electrostatic spinning and high temperature calcination reduction, the unique bean pod-like free-standing membrane is designed initially, filling SbSn dots into integrated carbon matrix including hollow carbon spheres and nitrogen-doped carbon fibers (B-SbSn/NCFs).	Nitrogen	263-271	brain expressed associated with NEDD4 1	Homo sapiens	119-123
11522683-10	2001	Increased cellular levels of the soluble N-ethylmaleimide attachment protein receptor (SNARE) proteins syntaxin 4 and vesicle-associated membrane protein (VAMP)-2 were also observed in the insulin-resistant SHRSP strain.	Nitrogen	41-42	syntaxin 4	Rattus norvegicus	103-113
35574130-0	2022	Recent Advances in Agronomic and Physio-Molecular Approaches for Improving Nitrogen Use Efficiency in Crop Plants.	Nitrogen	75-83	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	102-106
35629800-3	2022	The pilot test results demonstrated the remarkable performance of the combined sequential batch reactor (SBR) and C-MBR process, wherein the chemical oxygen demand (COD) and ammonia nitrogen (NH4+-N) removal rates reached 93% and 98.9%, respectively.	Nitrogen	182-190	translocator protein	Homo sapiens	116-119
11356843-2	2001	When cells are cultured with a good nitrogen source (glutamine, ammonia), Gln3p and Gat1p are restricted to the cytoplasm, whereas with a poor nitrogen source (proline), they localize to the nucleus, bind to the GATA sequences of NCR-sensitive gene promoters, and activate transcription.	Nitrogen	36-44	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	74-79
11440900-4	2001	The incorporation of dietary N into splanchnic proteins was thus predicted to reach 18, 24, and 35% of ingested N 8 h after MP, FMP, and SMP, respectively.	Nitrogen	29-30	family with sequence similarity 53 member B	Homo sapiens	137-140
35447118-6	2022	Importantly, N-glycomics of the immuno-purified integrin alpha6 from NSCLC-sEVs identified NSCLC-type N-glycans on this integrin subunit.	Nitrogen	13-14	integrin subunit alpha 6	Homo sapiens	48-63
11466382-8	2001	Transfer of serum into mice deficient in the generation of nitrogen or oxygen radicals (inducible NO synthase 2 or gp91(phox) genes, respectively) gave normal inflammatory responses, indicating that neither pathway is essential for disease induction.	Nitrogen	59-67	paired Ig-like receptor B	Mus musculus	115-119
35396977-6	2022	Our transcriptome data suggest that Cd triggers ROS production and photosynthesis decline associated with increased proteolysis through ubiquitin-proteasome system (UPS)- and chloroplast-proteases and in this way brings about re-mobilization of N and C stores into amino acids and sugars.	Nitrogen	245-246	ubiquitin	Raphanus sativus	136-145
11331291-1	2001	Gln3p is a GATA-type transcription activator of nitrogen catabolite repressible (NCR) genes.	Nitrogen	48-56	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-5
35346864-5	2022	Importantly, SLC7A5 expression in T and B cells was positively correlated with blood urea nitrogen and serum creatinine.	Nitrogen	90-98	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	Mus musculus	13-19
35089338-0	2022	The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis.	Nitrogen	111-119	syntaxin of plants 61	Arabidopsis thaliana	25-30
35089338-4	2022	Here, we report that the Arabidopsis thaliana trans-Golgi network/early endosome (TGN/EE) localized SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein SYP61 interacts with the transmembrane ubiquitin ligase ATL31, a key regulator of resistance to disrupted carbon (C)/nitrogen/(N)-nutrient conditions.	Nitrogen	303-311	syntaxin of plants 61	Arabidopsis thaliana	186-191
35089338-7	2022	SYP61 is ubiquitinated in plants, and its ubiquitination level is upregulated under low C/high N-nutrient conditions.	Nitrogen	95-96	syntaxin of plants 61	Arabidopsis thaliana	0-5
11331291-2	2001	Gln3p was recently found to be hyperphosphorylated in a TOR-dependent manner and resides in the cytoplasm in high quality nitrogen.	Nitrogen	122-130	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	0-5
35234919-0	2022	Concerted action: SYP61 and ATL31 cooperatively regulate the carbon/nitrogen nutrient response in Arabidopsis.	Nitrogen	68-76	syntaxin of plants 61	Arabidopsis thaliana	18-23
11331291-3	2001	In contrast, during nitrogen starvation or rapamycin treatment, Gln3p becomes rapidly dephosphorylated and accumulates in the nucleus, thereby activating nitrogen catabolite repression genes.	Nitrogen	20-28	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	64-69
11331291-3	2001	In contrast, during nitrogen starvation or rapamycin treatment, Gln3p becomes rapidly dephosphorylated and accumulates in the nucleus, thereby activating nitrogen catabolite repression genes.	Nitrogen	154-162	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	64-69
35277904-2	2022	The image depicts how a mixture of atmospheric gases such as CO2 , H2 , N2 and O2 can be selectively separated using a Cr metal-organic framework where spin state and spin coupling play a crucial role.	Nitrogen	72-74	spindlin 1	Homo sapiens	152-156
35277904-2	2022	The image depicts how a mixture of atmospheric gases such as CO2 , H2 , N2 and O2 can be selectively separated using a Cr metal-organic framework where spin state and spin coupling play a crucial role.	Nitrogen	72-74	spindlin 1	Homo sapiens	167-171
35043967-11	2022	These results indicate that ACO3 impacts submergence tolerance through integration of carbon and nitrogen metabolism via the mitochondrial TCA cycle and impacts stress signaling during acclimation to stress.	Nitrogen	97-105	aconitase 3	Arabidopsis thaliana	28-32
11402218-5	2001	AtXYL1 comprised three exons and encoded a peptide that was 915 amino acids long, with a potential signal peptide of 22 amino acids and eight possible N-glycosylation sites.	Nitrogen	151-152	alpha-xylosidase 1	Arabidopsis thaliana	0-6
35308014-1	2022	Objective: Phosphomannomutase 2 deficiency (PMM2-CDG) is a disorder of protein N-glycosylation with a wide clinical spectrum.	Nitrogen	79-80	phosphomannomutase 2	Homo sapiens	11-31
11244107-9	2001	Because at this locus coincidences of QTLs for grain yield, GS, NR activity, and nitrate content were also observed, we hypothesize that leaf nitrate accumulation and the reactions catalyzed by NR and GS are coregulated and represent key elements controlling nitrogen use efficiency in maize.	Nitrogen	259-267	nitrate reductase [NADH] 1	Zea mays	194-196
35308014-1	2022	Objective: Phosphomannomutase 2 deficiency (PMM2-CDG) is a disorder of protein N-glycosylation with a wide clinical spectrum.	Nitrogen	79-80	phosphomannomutase 2	Homo sapiens	44-48
35363007-1	2022	Nanodiamonds with embedded nitrogen-vacancy (NV) centers have emerged as promising magnetic field sensors, as hyperpolarizing agents in biological environments, as well as efficient tools for spin mechanics with levitating particles.	Nitrogen	27-35	spindlin 1	Homo sapiens	192-196
11308691-4	2001	The two-dimensional thermal expansion was determined to be (dA/dT)/A=1.8(+/-0.1)x10(-3) degrees C-1, which is comparable to the expansion in similar chain length bulk n-alkane rotator phases.	Nitrogen	12-13	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	96-99
35372102-4	2022	Sequencing of patient-derived Env genes revealed that potential N-linked glycosylation sites (PNGS) in V1 and V5 significantly increased over time.	Nitrogen	64-65	endogenous retrovirus group K member 20	Homo sapiens	30-33
11292525-3	2001	Mature IL-4 is a 12.8kDa protein containing six cysteine residues and two potential N-linked glycosylation sites and is highly homologous with other ruminant IL-4.	Nitrogen	84-85	interleukin 4	Mus musculus	7-11
35228263-0	2022	Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers.	Nitrogen	60-61	interleukin 15	Homo sapiens	78-83
11156884-10	2001	Similar results were obtained after intravenous administration of N:(6)-methyl-2"-deoxyadenosine-3":5"-bisphosphate, a selective antagonist of the P2Y(1) receptor, to wild-type mice.	Nitrogen	66-67	purinergic receptor P2Y, G-protein coupled 1	Mus musculus	147-162
35228263-1	2022	The oncotherapeutic promise of IL-15, a potent immunostimulant, is limited by a short serum t 1/2 The fusion protein N-803 is a chimeric IL-15 superagonist that has a >20-fold longer in vivo t 1/2 versus IL-15.	Nitrogen	117-118	interleukin 15	Homo sapiens	31-36
35228263-1	2022	The oncotherapeutic promise of IL-15, a potent immunostimulant, is limited by a short serum t 1/2 The fusion protein N-803 is a chimeric IL-15 superagonist that has a >20-fold longer in vivo t 1/2 versus IL-15.	Nitrogen	117-118	interleukin 15	Homo sapiens	137-142
35228263-1	2022	The oncotherapeutic promise of IL-15, a potent immunostimulant, is limited by a short serum t 1/2 The fusion protein N-803 is a chimeric IL-15 superagonist that has a >20-fold longer in vivo t 1/2 versus IL-15.	Nitrogen	117-118	interleukin 15	Homo sapiens	204-209
11160179-4	2001	We demonstrate that specific cleavage of GluR3 by granzyme B (GB), a serine protease released by activated immune cells, can generate the GluR3B autoantigenic peptide, but only if an internal N:-linked glycosylation sequon within the GluR3-GB recognition sequence (ISND*S) is not glycosylated.	Nitrogen	192-193	granzyme B	Homo sapiens	50-60
35148670-4	2022	Depth of split brain was greatly increased in DM group, and nitrogen-acetyl aspartic acid (NAA)/creatine (Cr), glutamic acid (Glu)/Cr, and choline (Cho)/Cr ratios were greatly reduced (P < 0.05).	Nitrogen	60-68	calbindin 2	Rattus norvegicus	106-108
35493753-8	2022	Variations were detected in the RBD and HVR regions, with a possible N-glycosylation site detected in isolate CK/CR/0632/19.	Nitrogen	69-70	cytidine/uridine monophosphate kinase 1	Homo sapiens	110-112
11160179-4	2001	We demonstrate that specific cleavage of GluR3 by granzyme B (GB), a serine protease released by activated immune cells, can generate the GluR3B autoantigenic peptide, but only if an internal N:-linked glycosylation sequon within the GluR3-GB recognition sequence (ISND*S) is not glycosylated.	Nitrogen	192-193	granzyme B	Homo sapiens	62-64
11160179-6	2001	These results suggest that GB/N:-glycon sites may escape normal tolerance mechanisms and contribute to autoantibody-mediated immune diseases.	Nitrogen	30-31	granzyme B	Homo sapiens	27-29
11361012-8	2001	A decreased rate of SSAO inhibition under N2 atmosphere to that obtained under O2 was produced upon preincubation of enzyme with 2-BEA, suggesting that oxidized intermediate was necessary for its inhibitory activity.	Nitrogen	42-44	amine oxidase copper containing 2	Homo sapiens	20-24
35211808-2	2022	The correct processing of the IGF-1Ea prohormone (proIGF-1Ea) and the IGF-1 receptor (IGF-1R) peptide precursor requires proper N-glycosylation.	Nitrogen	128-129	insulin like growth factor 1 receptor	Homo sapiens	70-84
35211808-2	2022	The correct processing of the IGF-1Ea prohormone (proIGF-1Ea) and the IGF-1 receptor (IGF-1R) peptide precursor requires proper N-glycosylation.	Nitrogen	128-129	insulin like growth factor 1 receptor	Homo sapiens	86-92
11212916-1	2001	Uptake of branched-chain amino acids by Saccharomyces cerevisiae from media containing a preferred nitrogen source is mediated by the permeases encoded by BAP2, BAP3, and VAP1/TAT1.	Nitrogen	99-107	branched-chain amino acid permease BAP2	Saccharomyces cerevisiae S288C	155-159
35189068-7	2022	FITM2 protein may be a 30 kDa hydrophobic protein with 26 phosphorylation sites and one potential N-glycosylated site.	Nitrogen	98-99	fat storage inducing transmembrane protein 2	Sus scrofa	0-5
11134547-10	2001	Levels of 1,N:(6)-ethenodeoxyadenosine and 3,N:(4)-ethenodeoxycytidine were about 70% higher in A/J and CD-1 mice than in C57BL/6 mice.	Nitrogen	12-13	CD1 antigen complex	Mus musculus	104-108
35216131-4	2022	NADPH, as produced from the action of glucose-6-phosphate dehydrogenase (G6PD), has an important role in redox homeostasis, serving as a cofactor for glutathione reductase in the recycling of glutathione from oxidized glutathione and for NADPH oxidases and nitric oxide synthases in the generation of reactive oxygen (ROS) and nitrogen species (RNS).	Nitrogen	327-335	2,4-dienoyl-CoA reductase 1	Homo sapiens	0-5
35216131-4	2022	NADPH, as produced from the action of glucose-6-phosphate dehydrogenase (G6PD), has an important role in redox homeostasis, serving as a cofactor for glutathione reductase in the recycling of glutathione from oxidized glutathione and for NADPH oxidases and nitric oxide synthases in the generation of reactive oxygen (ROS) and nitrogen species (RNS).	Nitrogen	327-335	glucose-6-phosphate dehydrogenase	Homo sapiens	38-71
35216131-4	2022	NADPH, as produced from the action of glucose-6-phosphate dehydrogenase (G6PD), has an important role in redox homeostasis, serving as a cofactor for glutathione reductase in the recycling of glutathione from oxidized glutathione and for NADPH oxidases and nitric oxide synthases in the generation of reactive oxygen (ROS) and nitrogen species (RNS).	Nitrogen	327-335	glucose-6-phosphate dehydrogenase	Homo sapiens	73-77
35216131-4	2022	NADPH, as produced from the action of glucose-6-phosphate dehydrogenase (G6PD), has an important role in redox homeostasis, serving as a cofactor for glutathione reductase in the recycling of glutathione from oxidized glutathione and for NADPH oxidases and nitric oxide synthases in the generation of reactive oxygen (ROS) and nitrogen species (RNS).	Nitrogen	327-335	2,4-dienoyl-CoA reductase 1	Homo sapiens	238-243
11188527-8	2000	Molecular mechanics calculations suggest that changes of even a single amino acid in lobster Cd3 beta N toward lobster Cd3 beta C--&gt;N or in mammalian MT1 or MT2 toward Cd3 beta-MT3 (GIF) can destabilize their structures.	Nitrogen	102-103	metallothionein 1I, pseudogene	Homo sapiens	153-156
34653477-6	2022	In addition, it was found that MCSC.S1 can simulate the simultaneous nitrification and denitrification (SND) process and contribute to 29.85% of the total nitrogen removal.	Nitrogen	155-163	solute carrier family 25 member 25	Homo sapiens	31-35
34653477-7	2022	16S gene-based analysis attributed this supplementary nitrogen removal to the enrichment of nitrification (i.e., Proteobacteria, Actinobacteria and Chloroflexi), denitrification of associated bacteria (i.e., Nitrospirota) in MCSC.S1 added reactor, and the increase in nitrogen recycling associated genes.	Nitrogen	54-62	solute carrier family 25 member 25	Homo sapiens	225-229
34653477-8	2022	These findings collectively demonstrate that the new MCSC.S1 could effectively enhance nitrogen removal efficiency in low C/N ratio wastewater.	Nitrogen	87-95	solute carrier family 25 member 25	Homo sapiens	53-57
35090502-9	2022	RESULT: In vivo, NQO1 overexpression reduced the urinary albumin/creatinine ratio (UACR) and blood urea nitrogen (BUN) level in db/db mice.	Nitrogen	104-112	NAD(P)H dehydrogenase, quinone 1	Mus musculus	17-21
11188527-8	2000	Molecular mechanics calculations suggest that changes of even a single amino acid in lobster Cd3 beta N toward lobster Cd3 beta C--&gt;N or in mammalian MT1 or MT2 toward Cd3 beta-MT3 (GIF) can destabilize their structures.	Nitrogen	102-103	metallothionein 2A	Homo sapiens	160-163
11152930-11	2000	Northern blot analysis demonstrated that the amount of P-selectin mRNA was markedly increased after treatment with ox-Lp(a) but not with n-LDL, ox-LDL and n-Lp(a).	Nitrogen	7-8	selectin P	Homo sapiens	55-65
35173546-5	2022	CD137-positive lymphatic vessels were involved in the development process of IgA nephropathy and positively correlated with serum creatinine, serum urea nitrogen, serum uric acid, and urinary 24 h total protein.	Nitrogen	153-161	TNF receptor superfamily member 9	Homo sapiens	0-5
11136295-5	2000	Reaction velocities and their relative abundance in HLM suggested that CYP1A2, 3A4, 2C19 and 2D6 were the most important contributors to N-dealkylation.	Nitrogen	137-138	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	71-77
11082192-7	2000	Considering that changes in PYC1 expression inversely correlated with changes in alpha-ketoglutarate concentration or in alpha-ketoglutarate/glutamate ratio following the nitrogen shift experiments, and taking into account the pivotal role of this metabolite in ammonium assimilation, it is suggested that changes in alpha-ketoglutarate or in the alpha-ketoglutarate/glutamate ratio might be implicated in triggering the nitrogen effects on PYC1 expression.	Nitrogen	171-179	pyruvate carboxylase 1	Saccharomyces cerevisiae S288C	28-32
11082192-7	2000	Considering that changes in PYC1 expression inversely correlated with changes in alpha-ketoglutarate concentration or in alpha-ketoglutarate/glutamate ratio following the nitrogen shift experiments, and taking into account the pivotal role of this metabolite in ammonium assimilation, it is suggested that changes in alpha-ketoglutarate or in the alpha-ketoglutarate/glutamate ratio might be implicated in triggering the nitrogen effects on PYC1 expression.	Nitrogen	421-429	pyruvate carboxylase 1	Saccharomyces cerevisiae S288C	28-32
11082192-8	2000	The physiological significance of the differential sensitivity of PYC1 and PYC2 genes with respect to the nitrogen source in the growth medium is also discussed.	Nitrogen	106-114	pyruvate carboxylase 1	Saccharomyces cerevisiae S288C	66-70
11073899-1	2000	Nitrogen-catabolic gene expression in Saccharomyces cerevisiae is regulated by the action of four GATA family transcription factors: Gln3p and Gat1p/Nil1p are transcriptional activators, and Dal80 and Deh1p/Gzf3p are repressors.	Nitrogen	0-8	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	133-138
11102520-8	2000	Thus, endomannosidase localization suggests that a quality control of N-glycosylation exists in the Golgi apparatus.	Nitrogen	70-71	mannosidase endo-alpha	Homo sapiens	6-21
10915793-8	2000	Brain mitoplasts from 10-day BNF-treated rats and also purified P450MT2 exhibited high N-demethylation activities for a number of neuroactive drugs, including trycyclic anti-depressants, anti-convulsants, and opiates.	Nitrogen	30-31	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	64-71
11087550-5	2000	In vitro metabolism by recombinant human cytochrome P450 revealed that a major biotransformation in humans is N-demethylation, catalyzed by CYP1A1, 1A2, 2C19, and 3A4.	Nitrogen	110-111	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	140-146
11018517-1	2000	We have expressed [U-(13)C,(15)N]-labeled Saccharomyces cerevisiae iso-1 cytochrome c C102T;K72A in Escherichia coli with a yield of 11 mg/l of growth medium.	Nitrogen	31-32	threonine ammonia-lyase ILV1	Saccharomyces cerevisiae S288C	67-72
10988254-2	2000	Human alpha1,3/4-fucosyltransferase III, -V, and -VI (hFucTIII, -V, and -VI) contain two conserved C-terminal N-glycosylation sites (hFucTIII: Asn154 and Asn185; hFucTV: Asn167 and Asn198; and hFucTVI: Asn153 and Asn184).	Nitrogen	110-111	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	133-141
10988254-10	2000	The present study demonstrates that hFucTIII, -V, and -VI require N-glycosylation at the two conserved C-terminal N-glycosylation sites for expression of full enzyme activity.	Nitrogen	66-67	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	36-44
10988254-10	2000	The present study demonstrates that hFucTIII, -V, and -VI require N-glycosylation at the two conserved C-terminal N-glycosylation sites for expression of full enzyme activity.	Nitrogen	114-115	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	36-44
10973692-3	2000	Analysis of the gp91(phox) amino acids sequence showed three potential N-linked glycosylation sites.	Nitrogen	71-72	paired Ig-like receptor B	Mus musculus	16-20
10960732-5	2000	Results from Western blot analysis, using antibodies raised against the purified beta-subunit of beta-conglycinin, revealed that accumulation of this protein was enhanced in non-nodulating soybeans when the plants were supplemented with nitrogen.	Nitrogen	237-245	beta-conglycinin beta subunit 1	Glycine max	81-113
10960732-7	2000	A one-time application of nitrogen to non-nodulating soybeans enhanced the accumulation of the 1.6 kb beta-conglycinin beta-subunit mRNA.	Nitrogen	26-34	beta-conglycinin beta subunit 1	Glycine max	102-131
10856884-11	2000	The rat PLP-K cDNA encodes for a predicted 228 amino acid protein containing a 31 amino acid signal peptide and one putative N-linked glycosylation site; the mouse PLP-M cDNA encodes for a predicted 228 amino acid protein containing a 28 amino acid signal peptide and one putative N-linked glycosylation site.	Nitrogen	16-17	prolactin family 2, subfamily B, member 1	Rattus norvegicus	8-13
10856884-11	2000	The rat PLP-K cDNA encodes for a predicted 228 amino acid protein containing a 31 amino acid signal peptide and one putative N-linked glycosylation site; the mouse PLP-M cDNA encodes for a predicted 228 amino acid protein containing a 28 amino acid signal peptide and one putative N-linked glycosylation site.	Nitrogen	125-126	prolactin family 2, subfamily B, member 1	Rattus norvegicus	8-13
10861906-10	2000	We also found that environmental conditions for meiosis finely regulate the transcript levels of KIN28 and CCL1, such that nitrogen starvation first elevates them but subsequent alkalization of medium decreases them.	Nitrogen	123-131	TFIIH complex serine/threonine-protein kinase subunit KIN28	Saccharomyces cerevisiae S288C	97-102
10991084-1	2000	MeV N+ and N2+ ions were used to induce Li+ desorption from LiF.	Nitrogen	4-6	LIF interleukin 6 family cytokine	Homo sapiens	60-63
10991084-1	2000	MeV N+ and N2+ ions were used to induce Li+ desorption from LiF.	Nitrogen	11-14	LIF interleukin 6 family cytokine	Homo sapiens	60-63
10828016-0	2000	High-affinity binding to the GM-CSF receptor requires intact N-glycosylation sites in the extracellular domain of the beta subunit.	Nitrogen	61-62	colony stimulating factor 2	Homo sapiens	29-35
10828016-5	2000	The present study investigated the role of N-glycosylation of the beta subunit on GM-CSF receptor function.	Nitrogen	43-44	colony stimulating factor 2	Homo sapiens	82-88
10828016-8	2000	A single mutation at any of the 3 consensus N-glycosylation sites abolished high-affinity GM-CSF binding in transfected COS cells.	Nitrogen	44-45	colony stimulating factor 2	Homo sapiens	90-96
10828016-11	2000	Intact N-glycosylation sites of GMRbeta in the extracellular domain are not required for cell surface targeting but are essential for high-affinity GM-CSF binding.	Nitrogen	7-8	colony stimulating factor 2	Homo sapiens	148-154
10837012-3	2000	Metabolic activation of IQ is a two-step process involving N-hydroxylation by CYP1A2 followed by esterification to a more reactive species capable of forming adducts with DNA.	Nitrogen	59-60	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	78-84
10852885-1	2000	Yvh1p, a dual-specific protein phosphatase induced specifically by nitrogen starvation, regulates cell growth as well as initiation and completion of sporulation.	Nitrogen	67-75	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	0-5
10808434-4	2000	The present route to the syntheses of various aminosugars with gluco- configurations from 5 alpha and 5 beta constitutes a novel method for the introduction of N-monoalkylated and N,N-dialkylated amines to the C-2 carbon of pyranoses in equatorial configurations.	Nitrogen	160-161	complement C2	Homo sapiens	210-213
11543516-2	2000	The results show the formation of a band at 2080 cm-1 in binary mixtures, NH3:CH4 and N2:CH4, which we attribute to HCN embedded in the organic residue formed by ion irradiation.	Nitrogen	86-88	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	116-119
10766803-6	2000	The backward transition from the closed to the open conformation was the reason for the identical rate-limiting steps during substitution of H(2)O in TC.Cbl.OH(2) for cyanide or azide according to the reaction TC(Cbl) --&gt; TC.Cbl.OH(2) + CN(-)/N(3)(-).	Nitrogen	241-242	Cbl proto-oncogene	Homo sapiens	153-156
10766803-6	2000	The backward transition from the closed to the open conformation was the reason for the identical rate-limiting steps during substitution of H(2)O in TC.Cbl.OH(2) for cyanide or azide according to the reaction TC(Cbl) --&gt; TC.Cbl.OH(2) + CN(-)/N(3)(-).	Nitrogen	241-242	Cbl proto-oncogene	Homo sapiens	213-216
10766803-6	2000	The backward transition from the closed to the open conformation was the reason for the identical rate-limiting steps during substitution of H(2)O in TC.Cbl.OH(2) for cyanide or azide according to the reaction TC(Cbl) --&gt; TC.Cbl.OH(2) + CN(-)/N(3)(-).	Nitrogen	241-242	Cbl proto-oncogene	Homo sapiens	213-216
10840970-4	2000	When the PhPN ligand is present in excess, it behaves as a monodentate phosphane ligand, since [Pd0(eta2-dba)(eta1-PhPN)2] is formed first by preferential cleavage of the Pd-N bond instead of the Pd olefin bond.	Nitrogen	12-13	secreted phosphoprotein 1	Homo sapiens	110-114
10791783-0	2000	Presence of a glycan at a potential N-glycosylation site, Asn-281, of bovine lactoferrin.	Nitrogen	36-37	lactotransferrin	Bos taurus	77-88
10791783-4	2000	On the other hand, a glycopeptide glycosylated at Asn-281 was only detected in hydrolysate of bovine lactoferrin-a, indicating that bovine lactoferrin-a possessed five N-glycosylated sites.	Nitrogen	168-169	lactotransferrin	Bos taurus	139-150
10713099-10	2000	Because N-glycosylation of PSGL-1 hinders trypsin cleavage, a recombinant form of PSGL-1 was generated in which all three potential N-glycosylation sites were mutated (DeltaN-PSGL-1).	Nitrogen	8-9	selectin P ligand	Homo sapiens	27-33
10713099-10	2000	Because N-glycosylation of PSGL-1 hinders trypsin cleavage, a recombinant form of PSGL-1 was generated in which all three potential N-glycosylation sites were mutated (DeltaN-PSGL-1).	Nitrogen	132-133	selectin P ligand	Homo sapiens	82-88
10713099-10	2000	Because N-glycosylation of PSGL-1 hinders trypsin cleavage, a recombinant form of PSGL-1 was generated in which all three potential N-glycosylation sites were mutated (DeltaN-PSGL-1).	Nitrogen	132-133	selectin P ligand	Homo sapiens	82-88
10720722-5	2000	N-demethylation was mainly catalyzed by CYP1A2, N-deethylation by CYP3A2/4.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	40-46
10720722-5	2000	N-demethylation was mainly catalyzed by CYP1A2, N-deethylation by CYP3A2/4.	Nitrogen	48-49	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	40-46
10692464-4	2000	Furthermore, when treated with an N-glycosylation inhibitor, tunicamycin, both tumor necrosis factor-alpha-activated bovine aortic endothelial cells and CHO-K1 cells stably expressing bovine LOX-1 (BLOX-1-CHO) exclusively produced a 32-kDa deglycosylated form of LOX-1.	Nitrogen	34-35	tumor necrosis factor	Bos taurus	79-106
10683447-0	2000	Simultaneous production of nitric oxide and peroxynitrite by plant nitrate reductase: in vitro evidence for the NR-dependent formation of active nitrogen species.	Nitrogen	145-153	nitrate reductase [NADH] 1	Zea mays	67-84
10683447-0	2000	Simultaneous production of nitric oxide and peroxynitrite by plant nitrate reductase: in vitro evidence for the NR-dependent formation of active nitrogen species.	Nitrogen	145-153	nitrate reductase [NADH] 1	Zea mays	112-114
10662709-4	2000	Despite greater total serum IGF-I levels, infusion of free IGF-I produced greater anabolic responses than IGF-I/BP-3 based on body weight, nitrogen balance, and jejunal cellularity.	Nitrogen	139-147	insulin-like growth factor 1	Rattus norvegicus	59-64
10662709-4	2000	Despite greater total serum IGF-I levels, infusion of free IGF-I produced greater anabolic responses than IGF-I/BP-3 based on body weight, nitrogen balance, and jejunal cellularity.	Nitrogen	139-147	insulin-like growth factor 1	Rattus norvegicus	59-64
10888037-4	2000	In this study we show that inhibition of N-linked glycosylation using tunicamycin or the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor lovastatin resulted in down-regulation of IGF-1R at the cell surface in Ewing"s sarcoma cell lines (RD-ES and ES-1 cells).	Nitrogen	41-42	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	89-146
10720114-7	2000	Intraduodenal fat significantly inhibited (P &lt; 0.005 versus control) gastrin-stimulated gastric acid secretion by 74% +/- 6%, but neither the lower (3% +/- 7%; NS) nor the higher PYY dose (1% +/- 10%; NS) induced any change in gastric acid output.	Nitrogen	204-206	gastrin	Homo sapiens	72-79
10631662-2	2000	Formation of an arylated nitrile, Ar1+N identical to CAr2 (where Ar1, Ar2 = aryl), is indicated by collision induced dissociation and comparison with the behavior of the authentic ion.	Nitrogen	38-39	transcription factor 20	Homo sapiens	34-37
10631662-2	2000	Formation of an arylated nitrile, Ar1+N identical to CAr2 (where Ar1, Ar2 = aryl), is indicated by collision induced dissociation and comparison with the behavior of the authentic ion.	Nitrogen	38-39	transcription factor 20	Homo sapiens	65-68
10617452-3	2000	The new technique is demonstrated using an (15)N-labeled protein sample, RAP 17-97 (N-terminal domain of alpha2-macroglobulin Receptor Associated Protein), in H(2)O at 500 MHz.	Nitrogen	47-48	LDL receptor related protein associated protein 1	Homo sapiens	105-153
10606508-3	1999	Infected Chinese hamster ovary cells expressed N-glycosylated Kv1.1 and 1.2 alpha subunits (M(r) approximately 60 and 62 K) that assembled and bound [(125)I]-alphaDTX with high affinity; an appreciable proportion appeared on the cell surface, with Kv1.2 showing a 5-fold enrichment in a plasma membrane fraction.	Nitrogen	47-48	potassium voltage-gated channel subfamily A member 1	Homo sapiens	62-67
10585852-0	1999	Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells.	Nitrogen	17-18	tyrosinase	Mus musculus	36-46
10604478-4	1999	Here we show that TOR prevents transcription of genes expressed upon nitrogen limitation by promoting the association of the GATA transcription factor GLN3 with the cytoplasmic protein URE2.	Nitrogen	69-77	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	151-155
10571250-1	1999	Arylamine N-acetyltransferase 1 (NAT1) conjugates several aromatic amines and their N-hydroxylated metabolites by N- or O-acetylation.	Nitrogen	10-11	N-acetyltransferase 1	Homo sapiens	33-37
10682915-2	1999	A short hydrophobic N-terminal peptide of hexokinase, readily cleavable by proteases, is absolutely required for its binding to all mitochondria.	Nitrogen	20-21	hexokinase	Saccharomyces cerevisiae S288C	42-52
10677824-3	1999	We present a pulse sequence, H(CN)N(H), for alleviating this problem in hydrogen bonds of the type NdH...Na-CH, in which the donor Nd nitrogen is correlated with the corresponding non-exchangeable C-H proton associated with the acceptor Na nitrogen.	Nitrogen	134-142	GLIS family zinc finger 3	Homo sapiens	99-102
10677824-3	1999	We present a pulse sequence, H(CN)N(H), for alleviating this problem in hydrogen bonds of the type NdH...Na-CH, in which the donor Nd nitrogen is correlated with the corresponding non-exchangeable C-H proton associated with the acceptor Na nitrogen.	Nitrogen	240-248	GLIS family zinc finger 3	Homo sapiens	99-102
10514491-4	1999	Diploid cells lacking Gpr1p, Plc1p, or Gpa2p fail to form pseudohyphae upon nitrogen depletion, and the filamentation defect of gpr1Delta and plc1Delta strains is rescued by activating a mitogen-activated protein kinase pathway via STE11-4 or by activating a cAMP pathway via overexpressed Tpk2p.	Nitrogen	76-84	Gpr1p	Saccharomyces cerevisiae S288C	22-27
10514491-6	1999	In conclusion, we have identified two physically interacting proteins, Gpr1p and Plc1p, as novel components of a nitrogen signaling pathway controlling the developmental switch from yeast-like to pseudohyphal growth.	Nitrogen	113-121	Gpr1p	Saccharomyces cerevisiae S288C	71-76
10527849-0	1999	Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates.	Nitrogen	59-67	farnesyl pyrophosphate synthase	Bos taurus	0-31
10564368-5	1999	In this study, it was further demonstrated that N/OFQ inhibition of calcium channel current was blocked by its specific antagonist PGN, [Phe1-psi(CH2-NH)-Gly2]nociceptin (1-13)-NH2, and the EC50 of the N/OFQ inhibition was approximately 10 nM, indicating that this effect was really mediated via the opioid receptor-like receptor.	Nitrogen	48-49	prepronociceptin	Rattus norvegicus	159-169
10511541-8	1999	These results suggest that Mks1p is involved in nitrogen control upstream of Ure2p as follows: NH(3) dash, vertical Mks1p dash, vertical Ure2p dash, vertical Gln3p --&gt; DAL5.	Nitrogen	48-56	Mks1p	Saccharomyces cerevisiae S288C	27-32
10840691-4	1999	In this work the AMBER N-N rotational barriers for all configurations of the parent, methyl and di-methyl substituted diformylhydrazines have been fitted to MP2/6-31 + G relative energies.	Nitrogen	23-24	tryptase pseudogene 1	Homo sapiens	157-165
10840691-4	1999	In this work the AMBER N-N rotational barriers for all configurations of the parent, methyl and di-methyl substituted diformylhydrazines have been fitted to MP2/6-31 + G relative energies.	Nitrogen	25-26	tryptase pseudogene 1	Homo sapiens	157-165
10512868-8	1999	Mutants expressing a nonphosphorylatable mutant Cdc28 or deficient for Swe1 exhibit low-nitrogen-dependent filamentous growth and are further induced by an ectopic MAPK signal.	Nitrogen	88-96	cyclin-dependent serine/threonine-protein kinase CDC28	Saccharomyces cerevisiae S288C	48-53
10823205-2	1999	[reaction: see text] The N-chloramine salt of tert-butylsulfonamide has been shown to be an efficient nitrogen source and the terminal oxidant for catalytic aminohydroxylation and aziridination of olefins, resembling closely Chloramine-T by its behavior in these catalytic reactions.	Nitrogen	102-110	telomerase reverse transcriptase	Homo sapiens	46-50
10464190-1	1999	Diploid Saccharomyces cerevisiae cells induce YVH1 expression and enter the developmental pathway, leading to sporulation when starved for nitrogen.	Nitrogen	139-147	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	46-50
10464190-4	1999	We conclude that (i) Yvh1p functions earlier than Mck1p and Ime1p in the signal transduction cascade that regulates sporulation and is triggered by nitrogen starvation and (ii) the role of Yvh1p in gametogenesis can be genetically distinguished from its role in vegetative growth.	Nitrogen	148-156	tyrosine protein phosphatase YVH1	Saccharomyces cerevisiae S288C	21-26
10462545-6	1999	Immunoblot analysis of human kidney cortex demonstrated that hOAT1 is an 80- to 90-kilodalton heterogeneous protein modified by abundant N-glycosylation.	Nitrogen	137-138	solute carrier family 22 member 6	Homo sapiens	61-66
10482686-11	1999	This type of GS gene regulation is reminiscent of the nitrogen regulatory system in bacteria, and suggests an evolutionary link between metabolic sensing and signaling in bacteria and plants.	Nitrogen	54-62	hypothetical protein	Arabidopsis thaliana	13-15
10454632-8	1999	Measurements of repair rates of nitrogen mustard N-alkylpurine adducts in the highly transcribed RPB2 gene demonstrate defects in the processing of mono-adducts in rad4, rad14 and mag1 strains.	Nitrogen	32-40	DNA-3-methyladenine glycosylase II	Saccharomyces cerevisiae S288C	180-184
10473105-4	1999	We now report that the DTIC N-demethylation involved in MTIC formation by human liver microsomes is catalyzed by CYP1A1, CYP1A2, and CYP2E1.	Nitrogen	28-29	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	113-119
10473105-4	1999	We now report that the DTIC N-demethylation involved in MTIC formation by human liver microsomes is catalyzed by CYP1A1, CYP1A2, and CYP2E1.	Nitrogen	28-29	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	121-127
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	61-65
10425605-3	1999	Using the model, it was possible to map four of five N-linked glycosylation sites in Fas and FasL and to study 10 of 11 residues previously identified by mutagenesis as important for binding.	Nitrogen	53-54	Fas ligand	Homo sapiens	93-97
10364244-0	1999	Temporal association of the N- and O-linked glycosylation events and their implication in the polarized sorting of intestinal brush border sucrase-isomaltase, aminopeptidase N, and dipeptidyl peptidase IV.	Nitrogen	28-29	sucrase-isomaltase	Homo sapiens	139-157
10364244-0	1999	Temporal association of the N- and O-linked glycosylation events and their implication in the polarized sorting of intestinal brush border sucrase-isomaltase, aminopeptidase N, and dipeptidyl peptidase IV.	Nitrogen	28-29	dipeptidyl peptidase 4	Homo sapiens	181-204
10359703-5	1999	Here, we have analysed the role of O-glycosylation in the apical sorting of sucrase-isomaltase (SI), a highly polarised N- and O-glycosylated intestinal enzyme, and the mechanisms underlying this process.	Nitrogen	120-121	sucrase-isomaltase	Homo sapiens	76-94
10359703-5	1999	Here, we have analysed the role of O-glycosylation in the apical sorting of sucrase-isomaltase (SI), a highly polarised N- and O-glycosylated intestinal enzyme, and the mechanisms underlying this process.	Nitrogen	120-121	sucrase-isomaltase	Homo sapiens	96-98
10399354-9	1999	Moreover, in the present study a relation could be assumed between the amount of CMP in the meal and the stimulation of luminal endogenous nitrogen secretion.	Nitrogen	139-147	matrilin 1	Homo sapiens	81-84
10329181-1	1999	The PutR protein of Agrobacterium tumefaciens positively regulates expression of the putA gene in response to exogenous proline, resulting in the utilization of proline as a source of carbon and nitrogen.	Nitrogen	195-203	putA	Agrobacterium tumefaciens	85-89
10235685-1	1999	The human nerve growth factor receptor (TrkA) contains four potential N-glycosylation sites that are highly conserved within the Trk family of neurotrophin receptors, and nine additional sites that are less well conserved.	Nitrogen	70-71	nerve growth factor receptor	Homo sapiens	10-38
10495887-4	1999	However, Rhag has an elongated C terminus and four N-glycosylation sites clustered on exoloop 1.	Nitrogen	51-52	Rh associated glycoprotein	Homo sapiens	9-13
10219963-13	1999	Recombinant CYP1A1, 1A2, 2B6, 2C19, 3A4 and 3A5 efficiently catalysed N-demethylation of zotepine.	Nitrogen	70-71	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	12-18
9931016-2	1999	The cDNA encoding a human ecto-apyrase (HB6), predicted to have seven N-linked glycosylation sites, was transiently expressed in mammalian COS cells and the resulting membrane preparations were treated with peptide N-glycosidase F (PNGase-F).	Nitrogen	6-7	ectonucleoside triphosphate diphosphohydrolase 1	Homo sapiens	26-38
9931016-2	1999	The cDNA encoding a human ecto-apyrase (HB6), predicted to have seven N-linked glycosylation sites, was transiently expressed in mammalian COS cells and the resulting membrane preparations were treated with peptide N-glycosidase F (PNGase-F).	Nitrogen	6-7	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	40-43
9931016-4	1999	The ecto-apyrase was also expressed in the presence of tunicamycin, which completely prevented N-linked glycosylation, resulting in a nonglycosylated core protein devoid of ATP and ADP hydrolyzing activity.	Nitrogen	95-96	ectonucleoside triphosphate diphosphohydrolase 1	Homo sapiens	4-16
10450333-0	1999	Insulin-like growth factor-I, but not growth hormone, is dependent on a high protein intake to increase nitrogen balance in the rat.	Nitrogen	104-112	insulin-like growth factor 1	Rattus norvegicus	0-28
10563909-3	1999	Nitrogen solubilities of RBPI were 53, 8, 62, 78, 82, and 80% at pHs 2.0, 4.0, 6.0, 8.0, 10.0, and 12.0, respectively.	Nitrogen	0-8	bactericidal permeability increasing protein	Homo sapiens	25-29
9891035-6	1999	Induction of AGP1 requires Uga35p(Dal81p/DurLp), a transcription factor of the Cys6-Zn2 family previously shown to participate in several nitrogen induction pathways.	Nitrogen	138-146	Dal81p	Saccharomyces cerevisiae S288C	34-40
10721199-0	1999	Physical control of the eutrophic response in the northern Adriatic Sea, illustrated by a nitrogen budget from ELNA data.	Nitrogen	90-98	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	68-71
9836623-8	1998	SAR studies revealed that the pyridine nitrogen atom and the nature and the position of the substituents on the pyridine ring were critically involved in the ability of the compounds to recognize and activate 5-HT1A receptors.	Nitrogen	39-47	5-hydroxytryptamine receptor 1A	Homo sapiens	209-215
9836521-3	1998	In this study, we examined the gene expression of VEGF mRNA in three tumor cell lines and in isolated whole and dispersed rat islets in vitro by Northern blot hybridization in normoxic (5% CO2, 95% humidified air) and hypoxic (1% O2, 5% CO2, 94% N2) culture conditions.	Nitrogen	246-248	vascular endothelial growth factor A	Rattus norvegicus	50-54
9811909-1	1998	PII is a protein allosteric effector in Escherichia coli and other bacteria that indirectly regulates glutamine synthetase at the transcriptional and post-translational levels in response to nitrogen availability.	Nitrogen	191-199	hypothetical protein	Arabidopsis thaliana	102-122
9811909-2	1998	Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites.	Nitrogen	46-54	hypothetical protein	Arabidopsis thaliana	180-200
9811909-2	1998	Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites.	Nitrogen	46-54	hypothetical protein	Arabidopsis thaliana	202-205
9811909-2	1998	Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites.	Nitrogen	144-152	hypothetical protein	Arabidopsis thaliana	180-200
9811909-2	1998	Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites.	Nitrogen	144-152	hypothetical protein	Arabidopsis thaliana	202-205
9811909-2	1998	Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites.	Nitrogen	144-152	hypothetical protein	Arabidopsis thaliana	180-200
9811909-2	1998	Data supporting the notion that plants have a nitrogen regulatory system(s) includes previous studies showing that the levels of mRNA for plant nitrogen assimilatory genes such as glutamine synthetase (GLN) and asparagine synthetase (ASN) are modulated by carbon and organic nitrogen metabolites.	Nitrogen	144-152	hypothetical protein	Arabidopsis thaliana	202-205
28308510-2	1998	Maximum rates of nitrogen fixation (26 ng N   cm-2 leaf area   h-1) - mainly due to the activity of two species of Scytonema (Cyanobacteria) - were measured in the rainy season in bright sunlight.	Nitrogen	17-25	H1.5 linker histone, cluster member	Homo sapiens	63-66
9774483-11	1998	These results suggest that polysialylation of NCAM is influenced by the difference between PST and STX in their preference for N-glycosylation sites on NCAM.	Nitrogen	46-47	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	Homo sapiens	99-102
9774483-11	1998	These results suggest that polysialylation of NCAM is influenced by the difference between PST and STX in their preference for N-glycosylation sites on NCAM.	Nitrogen	46-47	neural cell adhesion molecule 1	Homo sapiens	152-156
9778344-5	1998	The epsilon and eta nitrogens of the guanidinium side chain of Arg-39" from a neighboring dimer interact respectively with the C-2 carbonyl oxygen and one C-1 carboxylate oxygen of the adduct while the side chain of Arg-61" from the same dimer as the modified Pro-1 interacts with the C-1 carboxylate group in a bidentate fashion.	Nitrogen	20-29	lamin A/C	Homo sapiens	260-265
9748261-4	1998	In this report, we have examined whether Faa1p and Faa4p have distinct roles in affecting protein N-myristoylation as cells transition from growth in rich media to a growth-arrested state during nutrient deprivation (stationary phase).	Nitrogen	98-99	long-chain fatty acid-CoA ligase FAA1	Saccharomyces cerevisiae S288C	41-46
9762896-4	1998	LTBP1delta55 is a short form of LTBPIL which lacks 55 amino acids including two consensus N-glycosylation sites and LTBP1delta41 is a form of LTBP1 which lacks the 12th EGF-like repeat.	Nitrogen	90-91	latent transforming growth factor beta binding protein 1	Homo sapiens	0-5
9722584-6	1998	CILP has 30 cysteines and six putative N-glycosylation sites.	Nitrogen	39-40	cartilage intermediate layer protein	Homo sapiens	0-4
9825304-3	1998	Adjacent to the nitrogens, the C1/C1"-substituents are, however, found to affect the activity (inhibition) by their molecular size.	Nitrogen	16-25	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	31-37
9739616-7	1998	In the liver microsomes of a male rat at the 1st day after the treatment of CCl4, the addition of the anti-rat CYP 2C11 serum (30 microliters) also caused 25% inhibition of the formation of DMChp from S-(+)-Chp, but anti-rat CYP2C11 had no inhibitory effect on the rates of microsomal N-demethylation of R-(-)-enantiomer.	Nitrogen	285-286	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	111-119
9739616-8	1998	On the other hand, in the liver microsomes of a male rat at the 7th day after the treatment with CCl4, the anti-rat CYP2C11 serum had an inhibitory effect on the rates of microsomal N-demethylation of either S-(+)- or R-(-)-enantiomers again.	Nitrogen	182-183	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	116-123
9739616-10	1998	These results indicated that the changes of N-demethylation activities of Chp in the CCl4-induced hepatic injury were due to the variation of microsomal CYP2C11.	Nitrogen	44-45	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	153-160
9614085-5	1998	K+ starvation and nitrogen starvation hyperpolarize both TRK1 TRK2 and trk1Delta trk2Delta cells, thus suggesting that other proteins, in addition to Trk1p and Trk2p, participate in the control of the membrane potential.	Nitrogen	18-26	Trk2p	Saccharomyces cerevisiae S288C	160-165
9660190-8	1998	The nikC-inactivated mutant grew with L-lysine as sole source of nitrogen and carbon, indicating that L-lysine 2-aminotransferase is not required for lysine catabolism.	Nitrogen	65-73	relaxosome accessory protein	Escherichia coli	4-8
9593647-6	1998	Nitrogen balance was significantly increased by IGF-I in Experiment 1 as was carcass nitrogen content in Experiment 2, indicating that the increased growth was in lean tissue.	Nitrogen	0-8	IGF-I	Gallus gallus	48-53
9526564-5	1998	Spectroscopic studies with a modified form of human P450(17) alpha indicate that the inhibition process involves binding of steroidal azole nitrogen to the heme iron of the enzyme.	Nitrogen	140-148	cytochrome P450, family 17, subfamily a, polypeptide 1	Rattus norvegicus	52-66
9508791-4	1998	The dip5 mutation caused a several hundred-fold reduction of uptake of the two amino acids, both in cells grown on proline as a nitrogen source and in cells grown on ammonium.	Nitrogen	128-136	Dip5p	Saccharomyces cerevisiae S288C	4-8
9465086-3	1998	PSCA encodes a 123-aa protein with an amino-terminal signal sequence, a carboxyl-terminal GPI-anchoring sequence, and multiple N-glycosylation sites.	Nitrogen	127-128	prostate stem cell antigen	Homo sapiens	0-4
9417091-7	1998	In vitro binding assays established that syntaxin 7 in membrane extracts interacts with immobilized recombinant alpha-soluble N-ethylmaleimide-sensitive factor attachment proteins fused to glutathione S-transferase.	Nitrogen	126-127	syntaxin 7	Homo sapiens	41-51
9417091-7	1998	In vitro binding assays established that syntaxin 7 in membrane extracts interacts with immobilized recombinant alpha-soluble N-ethylmaleimide-sensitive factor attachment proteins fused to glutathione S-transferase.	Nitrogen	126-127	glutathione S-transferase kappa 1	Homo sapiens	189-214
9526091-2	1998	Ethanolamides of fatty acids are the most well-studied species of this group; an alternative pathway for their biosynthesis includes hydrolysis of N-acylated phosphatidylethanolamines by phospholipase D. Ethanolamides of fatty acids bind to the cannabinoid receptors of the central nervous system (CB1) or peripheral tissues (CB2) and can be considered as endogenous ligands of these receptors.	Nitrogen	147-148	cannabinoid receptor 2	Homo sapiens	326-329
9572394-1	1998	Multiple variant alleles of the human arylamine N-acetyltransferase genes, NAT1* and NAT2*, alter the capacity of individuals to metabolize arylamines by N-acetylation.	Nitrogen	48-49	N-acetyltransferase 1	Homo sapiens	75-79
10050263-3	1998	For IQ and PhIP, N-hydroxylation, catalyzed by microsomal cytochrome P-450 1A1 and/or 1A2, and then esterification, especially O-acetylation, are the principal steps leading to DNA adduct formation.	Nitrogen	17-18	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	58-78
9409822-5	1997	Mutations in LST4 and LST7 reduce the activity of the nitrogen-regulated permeases Gap1p and Put4p, whereas mutations in LST8 impair the activities of a broader set of amino acid permeases.	Nitrogen	54-62	Lst4p	Saccharomyces cerevisiae S288C	13-17
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	106-111
11671912-10	1997	The MP2 calculations indicate that at least one fluorine atom is required at the ring nitrogen in order to achieve nonplanarity.	Nitrogen	87-95	tryptase pseudogene 1	Homo sapiens	5-8
9325266-2	1997	The second domain of cytosolic glutathione S-transferases (GSTs) contains a strictly conserved N-capping box motif (Ser/Thr-Xaa-Xaa-Asp) at the beginning of alpha6-helix in the hydrophobic core of the molecule.	Nitrogen	95-96	glutathione S-transferase pi 1	Homo sapiens	59-63
9234685-11	1997	High-level MEP2 transcription requires at least one of the two GATA family factors Gln3p and Nil1p, which are involved in transcriptional activation of many other nitrogen-regulated genes.	Nitrogen	163-171	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	83-88
9323359-4	1997	CHA1 is regulated by transcriptional induction by serine and threonine, and enables yeast to utilize the hydroxyamino acids as sole nitrogen source.	Nitrogen	132-140	L-serine/L-threonine ammonia-lyase CHA1	Saccharomyces cerevisiae S288C	0-4
12223780-6	1997	In root plastids from barley starved of N for 3 d, G6PDH had a substantially reduced specific activity, had a lower Km for NADP, and was less inhibited by DTT than the enzyme from N-sufficient root plastids, indicating that there was some effect of N starvation on the G6PDH activity in barley root plastids.	Nitrogen	40-41	g6pdh	Hordeum vulgare	51-56
12223780-6	1997	In root plastids from barley starved of N for 3 d, G6PDH had a substantially reduced specific activity, had a lower Km for NADP, and was less inhibited by DTT than the enzyme from N-sufficient root plastids, indicating that there was some effect of N starvation on the G6PDH activity in barley root plastids.	Nitrogen	40-41	g6pdh	Hordeum vulgare	269-274
9201601-2	1997	This increased N-glycosylation was present in the face of decreased synthesis of hepatic cellular and secretory proteins evident from reduced leucine incorporation and diminished glycosyltransferase activity.	Nitrogen	15-16	protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)	Rattus norvegicus	179-198
9182588-0	1997	The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains.	Nitrogen	102-103	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	22-27
9182588-0	1997	The Ktr1p, Ktr3p, and Kre2p/Mnt1p mannosyltransferases participate in the elaboration of yeast O- and N-linked carbohydrate chains.	Nitrogen	102-103	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	28-33
9169429-3	1997	In a previous study, N-substituted homocysteine analogs were found to be potent inhibitors of PAM partially purified from conditioned medium of cultured rat medullary thyroid carcinoma CA-77 cells.	Nitrogen	21-22	peptidylglycine alpha-amidating monooxygenase	Rattus norvegicus	94-97
9202744-2	1997	N-Acetylation is catalyzed by two cytosolic N-acetyltransferases (NAT1 and NAT2) which detoxify many carcinogenic aromatic amines.	Nitrogen	0-1	N-acetyltransferase 1	Homo sapiens	66-70
9154155-10	1997	Furthermore, our results on BCATc provide support for the hypothesis that BCATs are also involved in nitrogen transfer from astrocytes to neurons.	Nitrogen	101-109	branched chain amino acid transaminase 1	Rattus norvegicus	28-33
9139799-1	1997	Using two separate methods, we have determined that all six potential sites for N-linked glycosylation on the rat lutropin/choriogonadotropin receptor (rLHR) contain carbohydrates.	Nitrogen	80-81	luteinizing hormone/choriogonadotropin receptor	Homo sapiens	114-150
9100025-2	1997	In this study, we show that N-acylated GCAP1 restored Ca2+ sensitivity of native and recombinant photoreceptor retGC1.	Nitrogen	28-29	guanylate cyclase 2D, retinal	Homo sapiens	111-117
9084436-3	1997	The purified ligand (termed HBGp82, for human brain galectin-1-binding polypeptide of 82,000 daltons) has an apparent molecular mass of 82 kDa and is glycosylated by N-linked biantennary complex structures.	Nitrogen	166-167	galectin 1	Homo sapiens	52-62
9385561-8	1997	The location of N-linked glycosylation sites in CD28/CD152 restricts the surface area available for binding.	Nitrogen	16-17	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	53-58
9113332-4	1997	In addition, an interaction site for the side-chain of Gln-165 in the human NK1 receptor that is probably involved in donating a hydrogen bond to the benzylamino nitrogen or benzylether oxygen of the quinuclidine and piperidine antagonists is explicitly postulated.	Nitrogen	162-170	tachykinin receptor 1	Homo sapiens	76-88
9076658-8	1997	This result indicated that rat CYP2C enzymes have a more rigid regioselectivity than rabbit CYP2C3 for the deamination/N-dealkylation of phenylisopropylamines.	Nitrogen	119-120	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	31-36
9323446-7	1997	In the frontoparietal cortex and hippocampus, MAP2 was significantly protected from degradation when isoflurane was used combined with nitrogen (N2).	Nitrogen	135-143	microtubule-associated protein 2	Rattus norvegicus	46-50
9323446-7	1997	In the frontoparietal cortex and hippocampus, MAP2 was significantly protected from degradation when isoflurane was used combined with nitrogen (N2).	Nitrogen	145-147	microtubule-associated protein 2	Rattus norvegicus	46-50
9148011-0	1997	Low doses of insulin-like growth factor-I improve nitrogen retention and food efficiency in rats with early cirrhosis.	Nitrogen	50-58	insulin-like growth factor 1	Rattus norvegicus	13-41
8973193-4	1996	Comparative studies of the spectral interaction and inhibitory effects of twelve compounds related to 1 with CYP 2C9 showed that the aniline function of 1 is responsible for the formation of the iron-nitrogen bond of the 429 nm-absorbing complex and is necessary for the inhibitory effects of 1.	Nitrogen	200-208	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	109-116
8973193-6	1996	A model for the binding of 1 in the CYP 2C9 active site is proposed; that takes into account three major interactions that should be at the origin of the high-affinity and specific inhibitory effects of 1 toward CYP 2C9: (i) the binding of its nitrogen atom to CYP 2C9 iron, (ii) an ionic interaction of its SO2N- anionic site with a cationic residue of CYP 2C9, and (iii) an interaction of its N-phenyl group with an hydrophobic part of the protein active site.	Nitrogen	244-252	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	36-43
8973193-6	1996	A model for the binding of 1 in the CYP 2C9 active site is proposed; that takes into account three major interactions that should be at the origin of the high-affinity and specific inhibitory effects of 1 toward CYP 2C9: (i) the binding of its nitrogen atom to CYP 2C9 iron, (ii) an ionic interaction of its SO2N- anionic site with a cationic residue of CYP 2C9, and (iii) an interaction of its N-phenyl group with an hydrophobic part of the protein active site.	Nitrogen	244-252	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	212-219
8973193-6	1996	A model for the binding of 1 in the CYP 2C9 active site is proposed; that takes into account three major interactions that should be at the origin of the high-affinity and specific inhibitory effects of 1 toward CYP 2C9: (i) the binding of its nitrogen atom to CYP 2C9 iron, (ii) an ionic interaction of its SO2N- anionic site with a cationic residue of CYP 2C9, and (iii) an interaction of its N-phenyl group with an hydrophobic part of the protein active site.	Nitrogen	244-252	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	212-219
8973193-6	1996	A model for the binding of 1 in the CYP 2C9 active site is proposed; that takes into account three major interactions that should be at the origin of the high-affinity and specific inhibitory effects of 1 toward CYP 2C9: (i) the binding of its nitrogen atom to CYP 2C9 iron, (ii) an ionic interaction of its SO2N- anionic site with a cationic residue of CYP 2C9, and (iii) an interaction of its N-phenyl group with an hydrophobic part of the protein active site.	Nitrogen	244-252	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	212-219
16844065-5	1996	GH and IGF-1 independently decreased postoperative urinary nitrogen excretion.	Nitrogen	59-67	insulin-like growth factor 1	Rattus norvegicus	7-12
16844065-6	1996	We conclude that both GH and IGF-1 improve postoperative nitrogen metabolism.	Nitrogen	57-65	insulin-like growth factor 1	Rattus norvegicus	29-34
8948523-2	1996	Compared with rats administered vehicle, rats administered ulinastatin (150,000 U/kg body weight) intravenously 30 min preischemia had significantly lower serum creatinine and blood urea nitrogen, and much less injury evident by examination of kidney histologies over the course of 48 h postreperfusion.	Nitrogen	187-195	alpha-1-microglobulin/bikunin precursor	Rattus norvegicus	59-70
8855939-0	1996	Disulfide structure and N-glycosylation sites of an extracellular domain of granulocyte-colony stimulating factor receptor.	Nitrogen	24-25	colony stimulating factor 3 receptor	Homo sapiens	76-122
8798755-1	1996	Cloning of the cDNA encoding a novel human protein- tyrosine phosphatase (PTP) called islet cell antigen-related PTP (IAR) predicts a receptor-like molecule with an extracellular domain of 614 amino acids containing a hydrophobic signal peptide, one potential N-glycosylation site, and an RGDS peptide which is a possible adhesive recognition sequence.	Nitrogen	17-18	protein tyrosine phosphatase receptor type N2	Homo sapiens	86-116
8798755-1	1996	Cloning of the cDNA encoding a novel human protein- tyrosine phosphatase (PTP) called islet cell antigen-related PTP (IAR) predicts a receptor-like molecule with an extracellular domain of 614 amino acids containing a hydrophobic signal peptide, one potential N-glycosylation site, and an RGDS peptide which is a possible adhesive recognition sequence.	Nitrogen	17-18	protein tyrosine phosphatase receptor type N2	Homo sapiens	118-121
11667621-4	1996	Instead the ring is closed by a bond from the indole nitrogen of Trp-1 to the beta-carbon of Trp-2.	Nitrogen	53-61	tRNA-Pro (anticodon AGG) 2-5	Homo sapiens	65-70
8853062-4	1996	Platelet-activating factor values were normalized per nanogram of lavage blood urea nitrogen.	Nitrogen	84-92	PCNA clamp associated factor	Homo sapiens	0-26
8794331-9	1996	We confirmed by several lines of evidence that N-linked glycosylation occludes a potentially functional virus-binding site in the CAT-1 protein of hamsters, thus contributing to resistance of that species.	Nitrogen	47-48	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	130-135
8794331-15	1996	These results suggest that N-linked glycosylation causes wild-type mCAT-1 heterogeneity and that a significant proportion is inaccessible to virus.	Nitrogen	27-28	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1	Mus musculus	67-73
8794736-9	1996	The guanido group (N eta 1, N eta 2) of Arg61 in the complex interacts with S delta of Met25i(P1") by possible hydrogen bonds between N and S atoms, accompanying a large positional shift of the side chain of Arg61-(S1") between the complexed and free forms of PPE.	Nitrogen	19-20	secreted phosphoprotein 1	Homo sapiens	21-35
8877032-6	1996	The two livers with the highest proportion of CYP2D6-mediated N-dealkylation had relatively high ratios of specific CYP2D6 to CYP1A2 activity.	Nitrogen	62-63	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	126-132
8913654-2	1996	METHODS: TAP-translocation was measured with a labeled reporter peptide containing an N-linked glycosylation acceptor site in Streptolysin O-permeabilized cells for a panel of HLA-B27 binding peptides.	Nitrogen	86-87	filamin B	Homo sapiens	9-12
8887900-0	1996	Effects of growth hormone and insulin-like growth factor 1 (IGF-1) treatments on the nitrogen metabolism and hepatic IGF-1-messenger RNA expression in postoperative parenterally fed rats.	Nitrogen	85-93	insulin-like growth factor 1	Rattus norvegicus	30-58
8887900-0	1996	Effects of growth hormone and insulin-like growth factor 1 (IGF-1) treatments on the nitrogen metabolism and hepatic IGF-1-messenger RNA expression in postoperative parenterally fed rats.	Nitrogen	85-93	insulin-like growth factor 1	Rattus norvegicus	60-65
8887900-7	1996	RESULTS: Both GH and IGF-1 attenuated body weight loss and nitrogen excretion and increased whole-body protein synthesis and spleen weight.	Nitrogen	59-67	insulin-like growth factor 1	Rattus norvegicus	21-26
11666716-1	1996	The infrared and Raman spectra of the NH(4)(+), K(+), and Cs(+) salts of N(NO(2))(2)(-) in the solid state and in solution have been measured and are assigned with the help of ab initio calculations at the HF/6-31G and MP2/6-31+G levels of theory.	Nitrogen	38-39	tryptase pseudogene 1	Homo sapiens	219-227
8921253-9	1996	Other structural features of CHL 1 shared between members of the L1 family are a high degree of N-glycosidically linked carbohydrates (approximately 20% of its molecular mass), which include the HNK-1 carbohydrate structure, and a pattern of protein fragments comprising a major 185 kDa band and smaller fragments of 165 and 125 kDa.	Nitrogen	96-97	cell adhesion molecule L1-like	Mus musculus	29-34
8805567-9	1996	We propose that when a nitrogen acceptor is present Cys1 is kept in the active conformation, explaining the phenomenon of substrate-induced activation of the enzyme, and that Arg26 is central in this coupling.	Nitrogen	23-31	cystin 1	Homo sapiens	52-56
8764403-1	1996	The recombinant N-terminal 107-amino acid polypeptide fragment 2-108 of the DnaJ molecular chaperone of Escherichia coli, which contains the J-domain (residues 2 to 76) and the Gly/Phe-rich region (residues 77 to 108), was uniformly labeled with nitrogen-15 and carbon-13.	Nitrogen	246-254	DnaJ	Escherichia coli	76-80
8663515-5	1996	Moreover, whereas phosphacan interactions with certain proteins are mediated at least in part by N-linked oligosaccharides on the proteoglycan, N-deglycosylation of phosphacan had no effect on its binding to TAG-1/axonin-1.	Nitrogen	97-98	protein tyrosine phosphatase receptor type Z1	Homo sapiens	18-28
8785501-2	1996	The new HCN-CCH-TOCSY scheme unambiguously links all sugar resonances to the base nitrogen.	Nitrogen	82-90	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	8-11
8638929-4	1996	Although no relationship was observed between the levels of CYP2B1/2 and CYP3A, ratios of CYP3A/CYP2B1 plus CYP2B2 contents were invariably higher with hepatocytes treated with N-methylated barbiturates than with the nonmethylated analogs.	Nitrogen	177-178	cytochrome P450, family 2, subfamily b, polypeptide 2	Rattus norvegicus	108-114
8691261-1	1996	UNLABELLED: We developed three radioactive acetylcholine analogs--N[14C]methyl-4-piperidyl acetate ([14C]MP4A), propionate ([14C]MP4P) and isobutyrate ([14C]MP4IB)--as radiotracers for measuring brain acetylcholinesterase (AchE) activity in vivo.	Nitrogen	1-2	acetylcholinesterase	Rattus norvegicus	201-221
8691261-1	1996	UNLABELLED: We developed three radioactive acetylcholine analogs--N[14C]methyl-4-piperidyl acetate ([14C]MP4A), propionate ([14C]MP4P) and isobutyrate ([14C]MP4IB)--as radiotracers for measuring brain acetylcholinesterase (AchE) activity in vivo.	Nitrogen	1-2	acetylcholinesterase	Rattus norvegicus	223-227
8612616-0	1996	The myeloid differentiation antigen CD14 is N- and O-glycosylated.	Nitrogen	44-45	LOW QUALITY PROTEIN: monocyte differentiation antigen CD14	Cricetulus griseus	36-40
8612616-1	1996	Contribution of N-linked glycosylation to different soluble CD14 isoforms.	Nitrogen	16-17	LOW QUALITY PROTEIN: monocyte differentiation antigen CD14	Cricetulus griseus	60-64
11666297-0	1996	Effect of Nitrogen Methylation on Cation and Anion Coordination by Hexa- and Heptaazamacrocycles.	Nitrogen	10-18	hexosaminidase subunit alpha	Homo sapiens	67-71
8636209-8	1996	In contrast, treatment of T cells with tunicamycin suggested that N-linked glycosylation of CD3 delta is required for TCR assembly.	Nitrogen	66-67	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	118-121
8712396-5	1996	Rates of N-dealkylated metabolite formation significantly correlated with nifedipine oxidation activity (a marker of CYP3A4 activity) for fentanyl and sufentanil (r = 0.93 and 0.87, n = 18, respectively), but not with the oxidation activity for ethoxyresorufin (CYP1A2), S-mephenytoin (CYP2C19), bufuralol (CYP2D6), or chlorzoxazone (CYP2E1).	Nitrogen	9-10	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	262-268
8678801-2	1996	N-hydroxylation catalyzed by CYP1A2 is the major pathway of metbolism of MeIQx and PhIP and is solely responsible for the generation of mutagenic species.	Nitrogen	0-1	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	29-35
8821656-0	1996	Over-expression of S. cerevisiae G1 cyclins restores the viability of alg1 N-glycosylation mutants.	Nitrogen	75-76	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	70-74
8821656-2	1996	We have identified mutations in ALG1 (ERC14), a gene required for N-glycosylation, which are inviable in a cln1 cln2 background but are rescued by over-expression of CLNs.	Nitrogen	66-67	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	32-36
8821656-2	1996	We have identified mutations in ALG1 (ERC14), a gene required for N-glycosylation, which are inviable in a cln1 cln2 background but are rescued by over-expression of CLNs.	Nitrogen	66-67	cyclin CLN1	Saccharomyces cerevisiae S288C	107-111
8754956-2	1996	The aim of this study was to assess the effect of NS on the serum neutrophil (NCA) and eosinophil (ECA) chemotactic activity and mononuclear cells-derived histamine releasing factor (HRF) activity in 14 patients with seasonal allergic asthma.	Nitrogen	50-52	CEA cell adhesion molecule 6	Homo sapiens	78-81
8557039-7	1995	atf1- cells are also sterile and this sterility appears to be due to a combination of two defects: first, upon nitrogen starvation the majority of atf1- cells fail to arrest in the G1 phase of the cell cycle and second, the induction of ste11+ expression is lost.	Nitrogen	111-119	activating transcription factor 1	Homo sapiens	0-4
8557039-7	1995	atf1- cells are also sterile and this sterility appears to be due to a combination of two defects: first, upon nitrogen starvation the majority of atf1- cells fail to arrest in the G1 phase of the cell cycle and second, the induction of ste11+ expression is lost.	Nitrogen	111-119	activating transcription factor 1	Homo sapiens	147-151
7503550-0	1995	Nitric oxide inhibition of lipoxygenase-dependent liposome and low-density lipoprotein oxidation: termination of radical chain propagation reactions and formation of nitrogen-containing oxidized lipid derivatives.	Nitrogen	166-174	polyunsaturated fatty acid lipoxygenase ALOX15	Oryctolagus cuniculus	27-39
7492299-1	1995	We studied the role of N-glycosylation of human lactoferrin (hLF) with respect to properties that are relevant to its antibacterial and anti-inflammatory activities.	Nitrogen	23-24	HLF transcription factor, PAR bZIP family member	Homo sapiens	61-64
7492299-9	1995	Furthermore, this analysis suggests that N-glycosylation heterogeneity in natural hLF and rhLF resides in the C-lobe.	Nitrogen	41-42	HLF transcription factor, PAR bZIP family member	Homo sapiens	82-85
8520223-6	1995	The average amide nitrogen T2 value for MLC2 increased from approximately 30 ms in the absence of CHAPS to approximately 56 ms in the presence of 25 mM CHAPS.	Nitrogen	18-26	myosin light chain 2	Homo sapiens	40-44
8585318-4	1995	The predicted Pmt3p contains 753 amino acids, four potential N-glycosylation sites and it is significantly homologous to Pmt1p, Pmt2p and Pmt4p.	Nitrogen	61-62	dolichyl-phosphate-mannose-protein mannosyltransferase	Saccharomyces cerevisiae S288C	138-143
8585318-5	1995	Pmt4p contains 762 amino acids and two potential N-glycosylation sites.	Nitrogen	49-50	dolichyl-phosphate-mannose-protein mannosyltransferase	Saccharomyces cerevisiae S288C	0-5
7559574-6	1995	Based on the amino acid sequence of phosphacan, it can be concluded that each of the tryptic peptides contains one potential N-glycosylation site (at Asn-232 and Asn-381), and analyses of the isolated glycopeptides demonstrated the presence of sialylated complex-type oligosaccharides.	Nitrogen	125-126	protein tyrosine phosphatase receptor type Z1	Homo sapiens	36-46
7559653-4	1995	Because bacterial binding is in part carbohydrate dependent, and the human platelet-activating factor (PAF) receptor bears a single N-linked glycosylation sequence in the second extracellular loop, we undertook studies to determine the role of this epitope in PAF receptor function.	Nitrogen	132-133	PCNA clamp associated factor	Homo sapiens	103-106
7559653-5	1995	Binding of pneumococci to COS cells transfected with the human PAF receptor is greatly reduced for a receptor mutant that bears no N-linked glycosylation site.	Nitrogen	131-132	PCNA clamp associated factor	Homo sapiens	63-66
7559653-9	1995	These data are supportive of pneumococcal binding on protein moiety(ies) of the PAF receptor and indicate that N-glycosylation facilitates expression of the protein on the cell membrane.	Nitrogen	111-112	PCNA clamp associated factor	Homo sapiens	80-83
7559469-8	1995	These data suggest that only the position 99 glycosylation site (Asn99-X-Thr101) in tHON is important in the reduction of binding of osteonectin to collagen V. Consistent with the binding data is the observation that both the N71Q and T73A mutant proteins migrate on SDS-polyacrylamide gel electrophoresis gels identically to wild-type tHON, suggesting that there is little or no N-glycosylation of residue 71 in wild-type osteonectin.	Nitrogen	87-88	secreted protein acidic and cysteine rich	Bos taurus	133-144
7559469-8	1995	These data suggest that only the position 99 glycosylation site (Asn99-X-Thr101) in tHON is important in the reduction of binding of osteonectin to collagen V. Consistent with the binding data is the observation that both the N71Q and T73A mutant proteins migrate on SDS-polyacrylamide gel electrophoresis gels identically to wild-type tHON, suggesting that there is little or no N-glycosylation of residue 71 in wild-type osteonectin.	Nitrogen	87-88	secreted protein acidic and cysteine rich	Bos taurus	423-434
8535396-9	1995	These results suggest that a CYP2D isozyme(s) is the primary enzyme in alprenolol 4-hydroxylation and N-desisopropylation in a lower substrate concentration range, and that the involvement of some male-specific P450 isozyme(s) other than CYP2C11 or CYP3A2 may cause the sex difference in the 4-hydroxylation.	Nitrogen	102-103	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	238-245
7736449-0	1995	DNA repair enzyme expression in chronic lymphocytic leukemia vis-a-vis nitrogen mustard drug resistance.	Nitrogen	71-79	DNA ligase 4	Homo sapiens	0-17
7542937-8	1995	Endo-N is an enzyme that specifically degrades PSA without affecting the NCAM polypeptide itself.	Nitrogen	5-6	neural cell adhesion molecule 1	Gallus gallus	73-77
7758938-2	1995	Experimental evidence indicated that the cloned fragment codes for proline dehydrogenase (EC 1.5.99.8) since RM2 cells transformed with a plasmid containing this sequence was able to survive on minimal medium supplemented with proline as the sole nitrogen and carbon sources.	Nitrogen	247-255	proline dehydrogenase	Mus musculus	67-88
7891726-3	1995	The products of the GLN3 and URE2 genes are required for the appropriate transcription of many genes in alternative nitrogen assimilatory pathways.	Nitrogen	116-124	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	20-24
7609275-5	1995	The cumulative nitrogen balance was significantly more positive for the IGF group (423.9 +/- 24.3 mg of nitrogen) than for the control group (290.8 +/- 26.0 mg of nitrogen).	Nitrogen	15-23	insulin-like growth factor 1	Rattus norvegicus	72-75
7609275-5	1995	The cumulative nitrogen balance was significantly more positive for the IGF group (423.9 +/- 24.3 mg of nitrogen) than for the control group (290.8 +/- 26.0 mg of nitrogen).	Nitrogen	104-112	insulin-like growth factor 1	Rattus norvegicus	72-75
7609275-5	1995	The cumulative nitrogen balance was significantly more positive for the IGF group (423.9 +/- 24.3 mg of nitrogen) than for the control group (290.8 +/- 26.0 mg of nitrogen).	Nitrogen	104-112	insulin-like growth factor 1	Rattus norvegicus	72-75
7726740-3	1995	A set of the alkyl substituent contributions (CHT1A) for prediction of the 5-HT1A affinity of N-alkyl derivatives of 1-arylpiperazines and related compounds have been defined on the basis of the Free-Wilson analysis.	Nitrogen	94-95	5-hydroxytryptamine receptor 1A	Homo sapiens	75-81
7818519-2	1995	For this purpose we studied three cell lines expressing HMG-CoA reductase molecules with introduced functional N-glycosylation sites located in the linker segments between transmembrane spans 1 and 2 (HMGal/Bins(-)), 3 and 4 (HMGal/Dins(-)) and 5 and 6 (HMGal/Fins(-)), all facing the ER lumen (Olender, E. H. and Simoni, R. D. (1992) J. Biol.	Nitrogen	111-112	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	56-73
7798155-1	1995	The cellular level and activity of the general amino acid permease, the product of the GAP1 gene of Saccharomyces cerevisiae, are regulated at the level of transcription by two systems, the products of URE2/GLN3 and NIL1 in response to the nitrogen sources of the growth medium and inactivation in response to the presence of glutamine or glutamate.	Nitrogen	240-248	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	207-211
7748436-0	1994	[Risk of anthropogenic nitrogen and phosphorus entry into the North Sea ecosystem].	Nitrogen	23-31	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	68-71
7984410-3	1994	DNA damage and its repair was studied in the essential dihydrofolate reductase (DHFR) gene after exposure of the cells to either ultraviolet (UV) irradiation or the alkylating agent nitrogen mustard.	Nitrogen	182-190	dihydrofolate reductase	Homo sapiens	55-78
7984410-3	1994	DNA damage and its repair was studied in the essential dihydrofolate reductase (DHFR) gene after exposure of the cells to either ultraviolet (UV) irradiation or the alkylating agent nitrogen mustard.	Nitrogen	182-190	dihydrofolate reductase	Homo sapiens	80-84
7851160-8	1994	Cells cryopreserved in liquid nitrogen for 1 week before processing showed &lt; 5% loss of PCNA and p120 fluorescence compared to freshly processed cells, but p105 fluorescence dropped 29% in cryopreserved MDA cells.	Nitrogen	30-38	proliferating cell nuclear antigen	Homo sapiens	91-95
7832976-2	1994	The compound is structurally related to the cholinesterase inhibitor heptylphysostigmine (MF 201) because the angular methyl group of the esoroline nucleus has been changed into a bridging carbon and the anilinic nitrogen has been replaced by a methylene group.	Nitrogen	213-221	butyrylcholinesterase	Homo sapiens	44-58
7927253-8	1994	In the eight extensive metabolizers the breath test indicated a dose-dependent increase of cytochrome P-450 1A2 activity of 8.5% +/- 15.0% (40 mg, mean +/- SD, NS) and 27.2% +/- 16.5% (120 mg, p = 0.002).	Nitrogen	160-162	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	91-111
7942810-6	1994	Serum levels of creatinine and urea nitrogen showed significant negative correlations with EGF, but not with ET and cAMP.	Nitrogen	36-44	epidermal growth factor	Homo sapiens	91-94
8090735-5	1994	The guest molecule is bound by the R-state monomer through the formation of two hydrogen bonds from the hydroxy group of Tylenol to the carbonyl oxygen and the nitrogen of A6 Cys and A11 Cys, respectively.	Nitrogen	160-168	DXS435E	Homo sapiens	183-186
7520996-1	1994	Sensitivity of yeast cells to the bifunctional alkylating agent nitrogen mustard (HN2) depends on two independently operating physiological mechanisms of cellular metabolism: dynamics of uptake of HN2 via choline permease, encoded in the gene HNM1/CTR, and repair of HN2-induced DNA damage.	Nitrogen	64-72	Hnm1p	Saccharomyces cerevisiae S288C	243-247
7992511-3	1994	The product encoded by the gene, designated TTP1, is a predicted type II membrane protein of 597 amino acid residues with a short cytoplasmic NH2-terminus, a membrane-spanning region and a large COOH-terminal region containing three potential N-glycosylation sites.	Nitrogen	142-143	ribitol xylosyltransferase 1	Homo sapiens	65-89
8037658-8	1994	Proton nuclear Overhauser enhancement spectroscopy demonstrated the proximity of leucine and tyrosine (within the consensus sequence) to the N-acetyl moiety found primarily within the pentasaccharide antithrombin III-binding site of heparin.	Nitrogen	141-142	serpin family C member 1	Homo sapiens	200-216
7958728-9	1994	The similarity of these ED50 data suggest that they share a similar chemical structure that binds to the 5-HT1A receptor, most likely it is "N-C-C-C-C-N" aliphatic backbone.	Nitrogen	141-142	5-hydroxytryptamine receptor 1A	Homo sapiens	105-120
7515860-6	1994	Expression of sLe(a) and sLe(x) antigens and binding to E-selectin were reduced by pre-treatment of SW1990 cells with the O-linked glycosylation inhibitor benzyl-alpha-GalNAc but not with the N-linked glycosylation inhibitor tunicamycin.	Nitrogen	171-172	selectin E	Homo sapiens	56-66
8207209-1	1994	IL-2 therapy can induce marked oxidative stress via reactive oxygen and nitrogen intermediates.	Nitrogen	72-80	interleukin 2	Mus musculus	0-4
7515065-5	1994	Here, we demonstrate that IL-1 beta diminished markedly the pp63 production by affecting its mRNA transcription and that the cytokine was able to modify the N-glycosylation process of the protein.	Nitrogen	95-96	fetuin B	Rattus norvegicus	60-64
8193137-8	1994	However, ACE synthesized without N-linked complex sugars and O-linked sugars can undergo normal transport and cleavage-secretion, and the underglycosylated protein is enzymatically active.	Nitrogen	33-34	angiotensin-converting enzyme	Oryctolagus cuniculus	9-12
8182543-1	1994	Studies in our laboratory have shown that the N-acetylation activity of the human term placenta is a predominantly attributable to the NAT1 form of arylamine N-acetyltransferase (NAT).	Nitrogen	46-47	N-acetyltransferase 1	Homo sapiens	135-139
8038132-1	1994	In the delta Asn20 Drosophila stock, the N-linked glycosylation site of opsin in R1-6 receptors (Rh1) is absent.	Nitrogen	41-42	neither inactivation nor afterpotential E	Drosophila melanogaster	72-77
8038132-1	1994	In the delta Asn20 Drosophila stock, the N-linked glycosylation site of opsin in R1-6 receptors (Rh1) is absent.	Nitrogen	41-42	neither inactivation nor afterpotential E	Drosophila melanogaster	97-100
8142406-15	1994	A sample of p21 in which the Thr residues were fully labeled with 13C and 15N yielded a value of 5.0 A for the distance from MnII to the amide nitrogen of Thr35, while the 13C signal is much smaller than expected if Thr35 were coordinated.	Nitrogen	143-151	H3 histone pseudogene 16	Homo sapiens	12-15
8166646-1	1994	The ALG1 gene of Saccharomyces cerevisiae encodes beta-1,4-mannosyltransferase, an essential membrane-associated enzyme involved in the assembly of dolichyl-linked oligosaccharide precursors for N-glycosylation [Albright and Robbins (1990) J. Biol.	Nitrogen	195-196	chitobiosyldiphosphodolichol beta-1,4 mannosyltransferase	Saccharomyces cerevisiae S288C	4-8
8166646-1	1994	The ALG1 gene of Saccharomyces cerevisiae encodes beta-1,4-mannosyltransferase, an essential membrane-associated enzyme involved in the assembly of dolichyl-linked oligosaccharide precursors for N-glycosylation [Albright and Robbins (1990) J. Biol.	Nitrogen	195-196	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	50-78
7958088-0	1994	[The relationship between the changes in insulin-like growth factor-1 (IGF-1) and the nutritional states evaluated by nitrogen balance in pregnant rats].	Nitrogen	118-126	insulin-like growth factor 1	Rattus norvegicus	41-69
7958088-0	1994	[The relationship between the changes in insulin-like growth factor-1 (IGF-1) and the nutritional states evaluated by nitrogen balance in pregnant rats].	Nitrogen	118-126	insulin-like growth factor 1	Rattus norvegicus	71-76
7958088-10	1994	The curious profiles of IGF-1 concentrations observed in pregnant rats might be due in part to the effects of nutritional changes between the maternal and fetal body, especially, the changes of protein metabolism represented by the nitrogen balance.	Nitrogen	232-240	insulin-like growth factor 1	Rattus norvegicus	24-29
8142445-6	1994	The formation constants between lipid P = O and anesthetic N-H were estimated in CCl4 from the spectral changes: 110 M-1 for lidocaine and 250 M-1 for dibucaine.	Nitrogen	59-60	C-C motif chemokine ligand 4	Homo sapiens	81-85
8145237-9	1994	The results were that the amide nitrogen approaches relatively close to the heme iron in CYP1A1 (3.64 +/- 0.51 A) whereas it is significantly further away (&gt; 4.5 A) in CYP2B1.	Nitrogen	32-40	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	89-95
8108141-5	1994	Using nine neighbouring probes, covering a region of about 395 kb around the c-myc gene, we were able to determine the extent and composition of c-myc amplicons in the HL60, NCI-N417, Colo320HSR, SkBr3 and the Sk-N-MC human tumour cell lines.	Nitrogen	174-175	MYC proto-oncogene, bHLH transcription factor	Homo sapiens	145-150
8106414-9	1994	Six potential N-linked glycosylation sites were present in the predicted DSP sequence.	Nitrogen	14-15	dentin sialophosphoprotein	Rattus norvegicus	73-76
8169523-6	1994	Mouse apoJ contains six potential N-glycosylation sites, a potential Arg-Ser cleavage site to generate alpha and beta subunits, a cluster of five cysteine residues in each subunit, three putative amphipathic helices, and four potential heparin-binding domains.	Nitrogen	34-35	clusterin	Mus musculus	6-10
8261468-9	1994	CYP1A2-catalyzed metabolism accounts for 91% of the elimination of ingested MeIQx and 70% of ingested PhIP, most likely via N-hydroxylation.	Nitrogen	124-125	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	0-6
8246168-2	1993	Administration of IGF-I at 0.01, 0.1 and 1 mg/kg by s.c. injection caused a 18.7, 33.0 and 66.5% increase of glomerular filtration rate and 54.8, 61.2 and 84.1% decrease of blood urea nitrogen, respectively, compared with the values in the saline-treated group 2 days after ischemia.	Nitrogen	184-192	insulin-like growth factor 1	Rattus norvegicus	18-23
8224160-3	1993	In the apg1 strain, which has normal vacuolar proteinases, nitrogen starvation did not induce protein degradation.	Nitrogen	59-67	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	7-11
8224160-4	1993	The apg1 mutant lost its viability faster than wild-type cells during nitrogen starvation.	Nitrogen	70-78	serine/threonine protein kinase ATG1	Saccharomyces cerevisiae S288C	4-8
8397508-6	1993	Inhibition of N-glycosylation with tunicamycin caused a dramatic intracellular degradation of these convertases within the endoplasmic reticulum, with the net effect of a reduction in the available activity of PC1 and PC2.	Nitrogen	14-15	proprotein convertase subtilisin/kexin type 1	Rattus norvegicus	210-213
8397508-6	1993	Inhibition of N-glycosylation with tunicamycin caused a dramatic intracellular degradation of these convertases within the endoplasmic reticulum, with the net effect of a reduction in the available activity of PC1 and PC2.	Nitrogen	14-15	proprotein convertase subtilisin/kexin type 2	Rattus norvegicus	218-221
8397508-7	1993	These results emphasize the importance of N-glycosylation in the folding and stability of PC1 and PC2.	Nitrogen	42-43	proprotein convertase subtilisin/kexin type 1	Rattus norvegicus	90-93
8397508-7	1993	These results emphasize the importance of N-glycosylation in the folding and stability of PC1 and PC2.	Nitrogen	42-43	proprotein convertase subtilisin/kexin type 2	Rattus norvegicus	98-101
8403225-0	1993	Differential inhibition of the DNA binding of transcription factors NF kappa B and OTF-1 by nitrogen mustard and quinacrine mustard: transcriptional implications.	Nitrogen	92-100	POU class 2 homeobox 1	Homo sapiens	83-88
8104555-4	1993	Here we report a comparative analysis of the site-specific N-glycosylation patterns from rat (Asn 23, 74, 98), mouse (Asn 23, 75, 99) and human (Asn 23, 60, 100) neural Thy-1.	Nitrogen	59-60	Thy-1 cell surface antigen	Homo sapiens	169-174
8258488-5	1993	In the investigation of causes, the use of a sapphire tip with the Nd-YAG laser and the cooling of the tip with N2 gas were thought to have contributed to the fatal outcome.	Nitrogen	112-114	TOR signaling pathway regulator	Homo sapiens	103-106
8104124-15	1993	The increase in N-demethylation by MC treatment appears to be due to elevation of CYP1A1/1A2 (P-450c/d).	Nitrogen	16-17	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	82-88
8104124-15	1993	The increase in N-demethylation by MC treatment appears to be due to elevation of CYP1A1/1A2 (P-450c/d).	Nitrogen	16-17	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	94-102
8104124-16	1993	Alternate substrates of CYP1A1/1A2 inhibited N-demethylation and reconstituted rat CYP 1A1-catalyzed N-demethylation.	Nitrogen	45-46	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	24-30
8104124-16	1993	Alternate substrates of CYP1A1/1A2 inhibited N-demethylation and reconstituted rat CYP 1A1-catalyzed N-demethylation.	Nitrogen	101-102	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	24-30
8104124-16	1993	Alternate substrates of CYP1A1/1A2 inhibited N-demethylation and reconstituted rat CYP 1A1-catalyzed N-demethylation.	Nitrogen	101-102	cytochrome P450, family 1, subfamily a, polypeptide 1	Rattus norvegicus	83-90
8104124-18	1993	Mab anti-CYP2C11/2C6 (P-450h/k) inhibited N-demethylation in PB, PCN, and control male rat liver microsomes, suggesting that CYP2C11 and/or CYP2C6 catalyze this reaction to some extent.	Nitrogen	42-43	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	9-16
7688884-3	1993	Initial data from primates revealed that G-CSF could ameliorate neutropenia following nitrogen mustard exposure.	Nitrogen	86-94	colony stimulating factor 3	Homo sapiens	41-46
8505328-4	1993	Ubc2-C88A, an inactive variant of Ubc2 in which the active-site Cys-88 has been replaced by Ala, is shown to retain the affinity for N-recognin.	Nitrogen	133-134	E2 ubiquitin-conjugating protein RAD6	Saccharomyces cerevisiae S288C	0-4
8505328-4	1993	Ubc2-C88A, an inactive variant of Ubc2 in which the active-site Cys-88 has been replaced by Ala, is shown to retain the affinity for N-recognin.	Nitrogen	133-134	E2 ubiquitin-conjugating protein RAD6	Saccharomyces cerevisiae S288C	34-38
8505328-6	1993	The two-hybrid (interaction cloning) technique was used to identify a approximately 170-residue C-terminal fragment of the 1,950-residue N-recognin as a Ubc2-interacting domain.	Nitrogen	137-138	E2 ubiquitin-conjugating protein RAD6	Saccharomyces cerevisiae S288C	153-157
8504812-0	1993	Primary structures of the N-linked carbohydrate chains from honeybee venom phospholipase A2.	Nitrogen	26-27	phospholipase A2	Apis mellifera	75-91
8463339-0	1993	G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.	Nitrogen	20-28	cyclin B1	Homo sapiens	78-87
8463339-0	1993	G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently.	Nitrogen	20-28	cyclin dependent kinase 1	Homo sapiens	88-92
24234786-3	1993	Horse heart cytochrome c could be fully N-actetylated and even on prolonged digestion with chymotrypsin underwent very little tryptic cleavage, in contrast to the native protein where this side reaction is extensive.	Nitrogen	40-41	cytochrome c, somatic	Equus caballus	12-24
8518023-1	1993	Recombinant interleukin-2 (rIL-2) can produce impairment of renal function with hypotension, fluid retention, elevated blood urea nitrogen, oliguria and low fractional sodium excretion; these side-effects are a common cause of reduction or interruption of rIL-2 infusion.	Nitrogen	130-138	interleukin 2	Rattus norvegicus	27-32
8380194-4	1993	The ouabain low-affinity isoform, alpha 1, exhibited high Na+ sensitivity [Ka of 3.88 +/- 0.25 mM Na+ and a Hill coefficient (n) of 1.98 +/- 0.13]; the ouabain high-affinity isoform, alpha 2, had two Na+ sensitivities, a high (Ka of 4.98 +/- 0.2 mM Na+ and n of 1.34 +/- 0.10) and a low (Ka of 28 +/- 0.5 mM Na+ and an n of 1.92 +/- 0.18) Na+ sensitivity activated above a threshold (22 +/- 0.3 mM Na+); and the ouabain very-high-affinity isoform, alpha 3, was resolved by two processes and appears to have two Na+ sensitivities (apparent Ka values of 3.5 and 20 mM Na+).	Nitrogen	10-11	adrenoceptor alpha 1D	Homo sapiens	34-41
8380078-6	1993	Synthesis of both gpI and gpIV included intermediary partially glycosylated forms and mature N- and O-linked final product.	Nitrogen	93-94	glycoprotein VI platelet	Homo sapiens	26-30
1331508-6	1992	The NH2-terminal immunoglobulin-like domain, domain 1, of the second monkey PVR, which lacks a putative N-glycosylation site, mediated poliovirus infection.	Nitrogen	4-5	PVR cell adhesion molecule	Homo sapiens	76-79
1331508-7	1992	In addition, a human PVR mutant without N-glycosylation sites in domain 1 also promoted viral infection.	Nitrogen	40-41	PVR cell adhesion molecule	Homo sapiens	21-24
1331527-2	1992	The effect of N glycosylation of the V domain of hPVR on binding and entry of poliovirus was studied.	Nitrogen	14-15	PVR cell adhesion molecule	Homo sapiens	49-53
1331527-4	1992	One of the cell lines expressed a mutant of hPVR, in which both asparagine residues of the two N-glycosylation sites of the V domain were changed to aspartate (N105D) and serine (N120S), respectively.	Nitrogen	95-96	PVR cell adhesion molecule	Homo sapiens	44-48
1331527-11	1992	The data suggest that N glycosylation of the V domain of hPVR is not essential for viral replication in human tissues and that differential glycosylation of hPVR at these sites is likely not a determinant of viral tissue tropism.	Nitrogen	22-23	PVR cell adhesion molecule	Homo sapiens	57-61
1431106-8	1992	These results indicate that IFN-gamma plus IL-2-induced tumoricidal activity is dependent upon the metabolism of L-arginine to reactive nitrogen intermediates, and they establish a role for TNF-alpha as a required intermediate for IL-2-dependent NO2- production and tumoricidal activity.	Nitrogen	136-144	interleukin 2	Mus musculus	43-47
1292236-3	1992	N positive dynamics in the content of beta 2-microglobulin was noted, peripheral blood values improved, the dysbalance of cellular and humoral immunity was controlled.	Nitrogen	0-1	beta-2-microglobulin	Homo sapiens	38-58
1329948-1	1992	Rhodopsin and all of the vertebrate visual pigments have a carboxylic acid residue, Glu113, in the third transmembrane segment that serves as a counterion to the protonated Schiff base nitrogen of the chromophore.	Nitrogen	185-193	rhodopsin	Bos taurus	0-9
1329948-9	1992	These results suggest that the Schiff base nitrogen in rhodopsin is located between residues 113 and 117 but there is enough flexibility in the protein to allow partial interaction with an Asp at position 120.	Nitrogen	43-51	rhodopsin	Bos taurus	55-64
1395096-4	1992	Sequential immunoprecipitation studies with the MoAb 44G4, which recognizes the O- and N-glycosylated homodimer endoglin, showed that both MoAbs recognize the same molecule on HUVE and phorbol myristate acetate (PMA)-stimulated U937 cells.	Nitrogen	87-88	endoglin	Homo sapiens	112-120
1282760-7	1992	Besides C-source, the other optimum conditions of dextranase formation were as follows: N-source, beef peptone; medium initial pH, 6.0-7.0; culture temperature, 28 degrees C; inoculum amount about 10%, and the organism was cultivated for 6 days on 200 r/min shaker in 250 ml flasker with 50 ml medium.	Nitrogen	88-89	dextranase	Purpureocillium lilacinum	50-60
16652938-0	1992	Cytokinin Is Required to Induce the Nitrogen-Dependent Accumulation of mRNAs for Phosphoenolpyruvate Carboxylase and Carbonic Anhydrase in Detached Maize Leaves.	Nitrogen	36-44	MLO-like protein 4	Zea mays	81-112
1584790-8	1992	Although other possibilities are not excluded, it is suggested that the modification of histidine residues in proteins by HNE involves a Michael-type addition of the imidazole nitrogen atom of histidine to the alpha, beta-unsaturated bond of HNE, followed by secondary reaction involving the aldehyde group with the C-4 hydroxyl group of HNE.	Nitrogen	176-184	complement C4A (Rodgers blood group)	Homo sapiens	316-319
1534022-0	1992	Requirement of N-linked glycosylation site in Drosophila rhodopsin.	Nitrogen	15-16	neither inactivation nor afterpotential E	Drosophila melanogaster	57-66
1534022-5	1992	These results establish that an N-linked glycosylation site, and likely glycosylation itself, plays a critical role in the maturation of Drosophila rhodopsin.	Nitrogen	32-33	neither inactivation nor afterpotential E	Drosophila melanogaster	148-157
1548676-8	1992	Additional improvements in activity were obtained by modification of the substituents on the tetrahydroquinoline nitrogen, bringing the Ki of three of the compounds below 15 nM against the human TS enzyme.	Nitrogen	113-121	thymidylate synthetase	Homo sapiens	195-197
1413125-1	1992	Three reactions (nucleophile substitution, thiolysis and N-deoxygenation) catalyzed by rat liver glutathione transferase have been studied using several N-heterylazimine inhibitors.	Nitrogen	57-58	glutathione S-transferase alpha 4	Rattus norvegicus	97-120
1553756-8	1992	In contrast, immunoblot analyses of hepatic cytosol revealed that a 25.5-kDa class mu GST band disappeared following treatment with pyridine, but was unaffected by treatment with other nitrogen heterocycles.	Nitrogen	185-193	hematopoietic prostaglandin D synthase	Rattus norvegicus	86-89
1553756-10	1992	The results suggest that nitrogen heterocycles differ in their ability to modulate glutathione S-transferase isozyme expression in rat and rabbit hepatic tissue and that rabbit hepatic GSTs are refractory to induction by agents such as pyrazine, phenobarbital, or 3-methylcholanthrene and hence these xenobiotics do not appear to be bifunctional inducers in this species.	Nitrogen	25-33	hematopoietic prostaglandin D synthase	Rattus norvegicus	83-108
1740433-8	1992	The C-SAA octapeptide specifies the first two residues of a NSS tripeptide, the only potential N-linked glycosylation site in the molecule.	Nitrogen	60-61	serum amyloid A4, constitutive	Homo sapiens	4-9
1371669-2	1992	Marked dose-dependent effects on body weight and nitrogen retention were produced, with the highest IGF-I dose, 695 micrograms/day, giving a 6 g increase in body weight over 7 days, compared with a 19 g loss in the dexamethasone-only group and an 18 g gain in pair-fed controls.	Nitrogen	49-57	insulin-like growth factor 1	Rattus norvegicus	100-105
1534688-0	1992	Relationships between cdc2 kinase, DNA cross-linking, and cell cycle perturbations induced by nitrogen mustard.	Nitrogen	94-102	cyclin dependent kinase 1	Homo sapiens	22-26
1657593-9	1991	Transcription of mam2 was induced only when strains containing functional mat1-M allele were cultured under conditions of nitrogen starvation.	Nitrogen	122-130	Nyv1p	Saccharomyces cerevisiae S288C	17-21
1928375-7	1991	Body weight gain, food utilization, and nitrogen balance during the treatment period were significantly increased in rats treated with IGF-I at both the lower and higher doses and in those treated with des-(1-3)IGF-I.	Nitrogen	40-48	insulin-like growth factor 1	Rattus norvegicus	135-140
1928375-8	1991	The improved nitrogen balance in the des-(1-3)IGF-I group could at least partly be explained by a diminished rate of muscle protein breakdown, as indicated by the reduced urinary excretion rate of 3-methylhistidine.	Nitrogen	13-21	insulin-like growth factor 1	Rattus norvegicus	46-51
1928375-10	1991	These results suggest that IGF-I may have beneficial effects on somatic growth and nitrogen balance in renal insufficiency, with des-(1--3)IGF-I being particularly effective in reducing the rate of muscle protein breakdown.	Nitrogen	83-91	insulin-like growth factor 1	Rattus norvegicus	27-32
1745030-1	1991	To maintain nitrogen equilibrium when prescribed a low protein diet (LPD), metabolic adaptations occur involving a reduction protein turnover, principally decreased muscle protein degradation.	Nitrogen	12-20	acyl-CoA synthetase bubblegum family member 1	Homo sapiens	69-72
1655529-4	1991	The predicted mRPTP mu protein consists of a 722 amino acid extracellular region, containing 13 potential N-glycosylation sites, a single transmembrane domain and a 688 amino acid intracellular part containing 2 tandem repeats homologous to the catalytic domains of other tyrosine phosphatases.	Nitrogen	106-107	protein tyrosine phosphatase, receptor type, M	Mus musculus	14-22
1680000-0	1991	N-linked neutral sugar chains of aminopeptidase N purified from rat small intestinal brush-border membrane.	Nitrogen	0-1	alanyl aminopeptidase, membrane	Rattus norvegicus	33-49
1680000-1	1991	Neutral oligosaccharides, which accounted for 74% of the total N-linked sugar chains released by hydrazinolysis of rat small intestinal aminopeptidase N, were investigated on a structural basis.	Nitrogen	0-1	alanyl aminopeptidase, membrane	Rattus norvegicus	136-152
1652057-1	1991	We found that cells of Saccharomyces cerevisiae have an elevated level of the NAD-dependent glutamate dehydrogenase (NAD-GDH; encoded by the GDH2 gene) when grown with a nonfermentable carbon source or with limiting amounts of glucose, even in the presence of the repressing nitrogen source glutamine.	Nitrogen	275-283	glutamate dehydrogenase (NAD(+))	Saccharomyces cerevisiae S288C	141-145
1652057-3	1991	This UAS was found to be separable from a neighboring element which is necessary for the nitrogen source regulation of the gene, and strains deficient for the GLN3 gene product, required for expression of NAD-GDH during growth with the activating nitrogen source glutamate, were unaffected for the expression of NAD-GDH during growth with activating carbon sources.	Nitrogen	247-255	nitrogen-responsive transcriptional regulator GLN3	Saccharomyces cerevisiae S288C	159-163
1712807-7	1991	The extent of THAM N-glycosylation, as measured by N-glycanase treatment of H194-112 immunoprecipitates, was found to be similar to that of human and rat DPP IV (i.e., approximately 20 kDa).	Nitrogen	19-20	dipeptidylpeptidase 4	Mus musculus	14-18
1859357-1	1991	A strategy that we originally used to identify an N-acetylated domain adjacent to the protein-linkage sequence of heparan sulphate proteoglycan (HSPG) [Lyon, Steward, Hampson &amp; Gallagher (1987) Biochem.	Nitrogen	50-51	glypican 3	Homo sapiens	114-143
1859357-1	1991	A strategy that we originally used to identify an N-acetylated domain adjacent to the protein-linkage sequence of heparan sulphate proteoglycan (HSPG) [Lyon, Steward, Hampson &amp; Gallagher (1987) Biochem.	Nitrogen	50-51	glypican 3	Homo sapiens	145-149
1859357-10	1991	7000 and 15,000) with the general formula: IdoA(2S)-GlcNSO3-[HexA-GlcNR]n-HexA-GlcNSO3-[Hex A-GlcNAc]9 12-GlcA-Gal-Gal-Xyl in which the average value for n is 1-2 for the 7000-Mr species and approx.	Nitrogen	6-7	hexosaminidase subunit alpha	Homo sapiens	61-65
1859357-10	1991	7000 and 15,000) with the general formula: IdoA(2S)-GlcNSO3-[HexA-GlcNR]n-HexA-GlcNSO3-[Hex A-GlcNAc]9 12-GlcA-Gal-Gal-Xyl in which the average value for n is 1-2 for the 7000-Mr species and approx.	Nitrogen	6-7	hexosaminidase subunit alpha	Homo sapiens	74-78
2070790-4	1991	From these findings it is concluded that the cobamide binding to intrinsic factor and transcobalamin is strongly affected by the Co-N coordination bonds of their lower cobalt nucleotide ligands.	Nitrogen	132-133	cobalamin binding intrinsic factor	Homo sapiens	65-81
1897978-2	1991	From the results of tunicamycin treatment and N-glycosidase F digestion, it was demonstrated that Namalwa-derived hGM-CSF was highly glycosylated at two potential N-glycosylation sites and several O-glycosylation sites as previously shown for naturally occurring hGM-CSF.	Nitrogen	46-47	colony stimulating factor 2	Homo sapiens	114-121
1897978-3	1991	We classified the hGM-CSF molecules into three groups according to the molecular weight corresponding to the degree of N-glycosylation: the molecules with two N-glycosylation sites occupied (designated 2N), the molecules with either site glycosylated (1N), and the molecules lacking N-glycosylation (0N).	Nitrogen	119-120	colony stimulating factor 2	Homo sapiens	18-25
1897978-3	1991	We classified the hGM-CSF molecules into three groups according to the molecular weight corresponding to the degree of N-glycosylation: the molecules with two N-glycosylation sites occupied (designated 2N), the molecules with either site glycosylated (1N), and the molecules lacking N-glycosylation (0N).	Nitrogen	159-160	colony stimulating factor 2	Homo sapiens	18-25
1897978-3	1991	We classified the hGM-CSF molecules into three groups according to the molecular weight corresponding to the degree of N-glycosylation: the molecules with two N-glycosylation sites occupied (designated 2N), the molecules with either site glycosylated (1N), and the molecules lacking N-glycosylation (0N).	Nitrogen	159-160	colony stimulating factor 2	Homo sapiens	18-25
1897978-9	1991	From these findings, we concluded that N-linked carbohydrate moieties of hGM-CSF play conflicting physiological roles in the efficacy of the protein in vivo but that O-linked carbohydrate moieties do not have such effects.	Nitrogen	39-40	colony stimulating factor 2	Homo sapiens	73-80
1853466-9	1991	Quantitation of bystander red-cell-bound C3d may allow the assessment of complement activation occurring by nitrogen bubbles in individuals undergoing decompression.	Nitrogen	108-116	endogenous retrovirus group K member 13	Homo sapiens	41-44
1900786-11	1991	The CRF antagonist also blocked the ability of IL-1a to increase cortisol secretion: mean cortisol concentrations were 28.6 +/- 1.4 micrograms/dl (NS vs. saline).	Nitrogen	147-149	interleukin-1 alpha	Macaca mulatta	47-52
2016714-3	1991	These were designed on the basis of molecular modeling to the known X-ray structure of Escherichia coli DHFR, in an effort to determine whether one could drastically alter the diamino configuration by placing one amino substituent in a 5-membered nitrogen-containing ring and the second in the ortho position of a fused ring and still inhibit DHFR significantly.	Nitrogen	247-255	Dihydrofolate reductase	Escherichia coli	104-108
2059905-4	1991	Metyrapone, alpha-naphthoflavone, phenelzine, mercuric chloride, and nitrogen significantly inhibited the reaction indicating the involvement of the cytochrome P-450 monooxygenase.	Nitrogen	69-77	cytochrome P450, family 2, subfamily j, polypeptide 3	Rattus norvegicus	149-179
1645456-1	1991	We examined the role of N-linked glycosylation of the insulin-like growth factor-II (IGF-II)/mannose 6-phosphate (Man-6-P) receptor in binding of [125I]IGF-II to the receptor.	Nitrogen	24-25	insulin like growth factor 2	Homo sapiens	54-83
1987998-2	1991	We investigated the short-term effects of N-LDL and Ox-LDL on the formation of endothelium-derived relaxing factor (EDRF) in native and cultured endothelial cells and on its inactivation after release from the cells.	Nitrogen	42-43	alpha hemoglobin stabilizing protein	Homo sapiens	79-114
1987998-2	1991	We investigated the short-term effects of N-LDL and Ox-LDL on the formation of endothelium-derived relaxing factor (EDRF) in native and cultured endothelial cells and on its inactivation after release from the cells.	Nitrogen	42-43	alpha hemoglobin stabilizing protein	Homo sapiens	116-120
1987998-5	1991	N-LDL reduced the EDRF-mediated vasodilations of the detector segments by 38.5 +/- 5.3%, and Ox-LDL, by 55.5 +/- 4.6%.	Nitrogen	0-1	alpha hemoglobin stabilizing protein	Homo sapiens	18-22
1999680-1	1991	The ability of insulin-like growth factor-I (IGF-I) to protect against losses of body protein during periods of dietary nitrogen restriction has been evaluated in young rats.	Nitrogen	120-128	insulin-like growth factor 1	Rattus norvegicus	15-43
1999680-1	1991	The ability of insulin-like growth factor-I (IGF-I) to protect against losses of body protein during periods of dietary nitrogen restriction has been evaluated in young rats.	Nitrogen	120-128	insulin-like growth factor 1	Rattus norvegicus	45-50
1999680-4	1991	Plasma IGF-I levels were reduced by 60% following nitrogen restriction, a reduction that was partly prevented by IGF-I administration, especially at the higher dose, but not measurably by des(1-3)IGF-I.	Nitrogen	50-58	insulin-like growth factor 1	Rattus norvegicus	7-12
1999680-12	1991	These results suggest that exogenous IGF-I and especially des(1-3)IGF-I can partly protect body protein reserves during nitrogen restriction.	Nitrogen	120-128	insulin-like growth factor 1	Rattus norvegicus	37-42
1999680-12	1991	These results suggest that exogenous IGF-I and especially des(1-3)IGF-I can partly protect body protein reserves during nitrogen restriction.	Nitrogen	120-128	insulin-like growth factor 1	Rattus norvegicus	66-71
1886079-6	1991	These conformationally restricted molecules demonstrated moderate stereospecificity in their interaction with the 5-HT1A binding site, which was enhanced in compounds with larger nitrogen substituents.	Nitrogen	179-187	5-hydroxytryptamine receptor 1A	Homo sapiens	114-120
1824714-3	1991	The nucleotide sequence of GAS1 predicts a 60-kDa polypeptide with a cleavable N-terminal signal sequence, potential sites for N- and O-linked glycosylation, and a C-terminal hydrophobic domain.	Nitrogen	79-80	1,3-beta-glucanosyltransferase GAS1	Saccharomyces cerevisiae S288C	27-31
1725860-7	1991	Both rat and human IGFBP-3 possess multiple N-linked glycosylation sites at the mid-region of the molecule, which accounts for their apparent molecular size being larger than the calculated molecular weight, based on the amino acid sequence.	Nitrogen	44-45	insulin like growth factor binding protein 3	Homo sapiens	19-26
15374469-5	1990	At liquid nitrogen temperature (-196 degrees C), the ESR signal of O2(-*) radicals could be observed directly, thus allowing us to estimate the scavenging activity of ID-O and ID-H.	Nitrogen	10-18	indoleamine 2,3-dioxygenase 1	Homo sapiens	167-171
15374469-5	1990	At liquid nitrogen temperature (-196 degrees C), the ESR signal of O2(-*) radicals could be observed directly, thus allowing us to estimate the scavenging activity of ID-O and ID-H.	Nitrogen	10-18	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	176-180
1698930-1	1990	The monoclonal L5 antibody reacts with an N-glycosidically linked carbohydrate structure which is present on the neural cell adhesion molecule L1, neural chondroitin sulfate proteoglycans, and other not yet identified glycosylated proteins.	Nitrogen	42-43	L1 cell adhesion molecule	Mus musculus	113-145
2118158-7	1990	Almost all of the mass of the M1/69-J11d Ag accumulates through extensive N- and O-linked glycosylation at multiple sites in the short peptide.	Nitrogen	74-75	cholinergic receptor, muscarinic 1, CNS	Mus musculus	30-35
2400399-0	1990	Effect of N-methylation on the modulation by synthetic peptides of the activity of the complement-factor-B-derived serine proteinase CVFBb.	Nitrogen	10-11	complement factor B	Cavia porcellus	87-106
2143984-5	1990	Furthermore, it was found that the amino acid sequence deduced from the nucleotide sequence of the cDNA insert contained four potential N-glycosylation sites and copper-binding amino acid residues located in four regions where the sequence was identical or nearly identical to those of the other known blue multicopper oxidases Neurospora crassa laccase and human ceruloplasmin.	Nitrogen	101-102	ceruloplasmin	Homo sapiens	364-377
2198284-13	1990	Selective periodate oxidation showed that both the inner and outer sialic acid residues of GD3 incorporated 3H-label in the in vitro reaction, and showed similar turnover of N-acetylation in the pulse-chase study.	Nitrogen	174-175	GRDX	Homo sapiens	91-94
2166945-3	1990	The 142-amino acid extracellular domain (including signal peptide) of R-PTP-alpha is marked by a high serine/threonine content (32%) as well as eight potential N-glycosylation sites but displays no similarity to known proteins.	Nitrogen	160-161	protein tyrosine phosphatase, receptor type, A	Mus musculus	70-81
2079883-3	1990	In the present study we evaluated, by means of a RIA method, the concentration of gastrin (ng/g of protein nitrogen) in homogenized gastroduodenal biopsies in 127 patients with peptic ulcer and in 12 dyspeptic patients.	Nitrogen	107-115	gastrin	Homo sapiens	82-89
2113054-6	1990	The role of glycosylation in the expression of sCD4 was investigated by mutagenesis of the constructs to remove each of the two N-linked glycosylation sites in turn and both together.	Nitrogen	128-129	stearoyl-coenzyme A desaturase 4	Rattus norvegicus	47-51
2113054-9	1990	The disulfide bonds of sCD4 were determined to be within domains 1, 2, and 4 and isolation of glycopeptides showed that both N-linked sites were glycosylated.	Nitrogen	125-126	stearoyl-coenzyme A desaturase 4	Rattus norvegicus	23-27
2341393-12	1990	The number of potential N-glycosylation sites on gp120 is on the order of 20, but the oligosaccharide structures are far more numerous.	Nitrogen	24-25	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	49-54
16667412-1	1990	We have utilized the cellular differentiation gradient of the developed, youngest leaf to examine the regulation by nitrogen of levels of phosphoenolpyruvate carboxylase (PEPCase), pyruvate orthophosphate dikinase (PPDK), and ribulose 1,5-bisphosphate carboxylase in maize (Zea mays L.).	Nitrogen	116-124	MLO-like protein 4	Zea mays	171-178
16667412-2	1990	The protein whose level regulated most preferentially by N availability was PEPCase, followed by PPDK, and the changes in level occurred most conspicuously at the photosynthetically maturing cells.	Nitrogen	57-58	MLO-like protein 4	Zea mays	76-83
1690131-7	1990	Expression of distinct forms of the T cell receptor gamma/delta, disulfide-bonded N-glycosylated surface heterodimers of under reducing conditions 38/40 and 37/40 kDa, respectively, hallmarks the CD2-86D+ and CD2-86D- subsets both as T lymphocytes.	Nitrogen	82-83	CD2 molecule	Sus scrofa	196-199
1690131-7	1990	Expression of distinct forms of the T cell receptor gamma/delta, disulfide-bonded N-glycosylated surface heterodimers of under reducing conditions 38/40 and 37/40 kDa, respectively, hallmarks the CD2-86D+ and CD2-86D- subsets both as T lymphocytes.	Nitrogen	82-83	CD2 molecule	Sus scrofa	209-212
2384003-4	1990	These results support the supposition that only a small population of S-Ag is glycosylated (probably in N-glycosylated form), and the sugar moiety is located in the C-terminal half of the molecule.	Nitrogen	104-105	S-antigen visual arrestin	Bos taurus	70-74
33801748-2	2021	Target gases included both oxygen and carbon monoxide in nitrogen-based sample gas mixtures.	Nitrogen	57-65	gastrin	Homo sapiens	7-10
32007578-0	2020	Development and characterisation of a peptidergic N-and C-terminally stabilised mammalian NPY1R agonist which protects against diabetes induction.	Nitrogen	50-51	neuropeptide Y receptor Y1	Homo sapiens	90-95
22575017-4	2012	Here, (15)N-(1)H HSQC NMR spectroscopy demonstrates that 0118 indeed targets galectin-1 at a site away from the lectin"s carbohydrate binding site and thereby attenuates lactose binding to the lectin.	Nitrogen	10-11	galectin 1	Homo sapiens	77-87
34461547-9	2022	The total inorganic nitrogen (TIN) removal rate reached 4.45 mg/L h-1, which compared to other microalgal species, the nitrogen removal rate and biomass yield were 7.8- and 4.9-fold higher, respectively.	Nitrogen	20-28	procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	Homo sapiens	64-69
34461547-9	2022	The total inorganic nitrogen (TIN) removal rate reached 4.45 mg/L h-1, which compared to other microalgal species, the nitrogen removal rate and biomass yield were 7.8- and 4.9-fold higher, respectively.	Nitrogen	119-127	procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	Homo sapiens	64-69
34826585-1	2022	OBJECTIVE: SNAP-25 is one of the key proteins involved in formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes that are at the core of hormonal secretion and synaptic transmission.	Nitrogen	79-80	synaptosomal-associated protein 25	Mus musculus	11-18
34637869-10	2022	The N-/S-containing compounds mainly included NH3, HCN, H2S, SO2, COS in the gas phase and amines, indoles, pyridines, nitriles, thiophenes in liquid phase.	Nitrogen	4-5	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	51-54
34799437-5	2022	Results Urat1-Uox DKO mice had uricosuric effects and elevated levels of plasma creatinine (Cr) and blood urea nitrogen (BUN) as renal injury markers, and decreased Cr clearance (CLCr) observed in a forced swimming test.	Nitrogen	111-119	solute carrier family 22 (organic anion/cation transporter), member 12	Mus musculus	8-13
34418836-0	2022	Monolayer PC3: A promising material for environmentally toxic nitrogen-containing multi gases.	Nitrogen	62-70	chromobox 8	Homo sapiens	10-13
34418836-2	2022	The present article addresses a detailed investigation on the potential of the monolayer PC3 compound as a possible sensor material for environmentally toxic nitrogen-containing gases (NCGs), namely NH3, NO, and NO2.	Nitrogen	158-166	chromobox 8	Homo sapiens	89-92
34752954-2	2022	To systematically explore the relationship between the number or position of nitrogen atoms and their optical properties and biological properties, five series of new N, O-coordinated organo-difluoroboron probes were introduced as binding scaffolds for Abeta plaques and Tau tangles.	Nitrogen	77-85	microtubule associated protein tau	Homo sapiens	271-274
34860005-6	2022	Microinjection of N-protein in SH-SY5Y cells disturbed the alpha-synuclein proteostasis and increased cell death.	Nitrogen	18-19	synuclein alpha	Homo sapiens	59-74
34850458-6	2022	The shifting and intensity enhancement of the CCl2 band manifests the back-donation and conjugation effect, which are the result of the presence of nitrogen atom adjoining the dichloromethyl groups and the oxygen in the sulfur dioxide group attached among the amino group and the chlorophenyl ring, respectively, which enhances bioactivity.	Nitrogen	148-156	C-C motif chemokine ligand 2	Homo sapiens	46-50
34969094-4	2022	For example, it is now known that NGLY1 can also act as an "editing enzyme" to convert N-glycosylated asparagine residues to aspartate residues, thus introducing negative charges into a core peptide and modulating the function of the target molecule.	Nitrogen	87-88	N-glycanase 1	Homo sapiens	34-39
33345705-6	2021	The possible mechanism analysis demonstrated that over-production of reactive oxygen species and reactive nitrogen species effectively regulated expression levels of bacterial outer membrane protein and conjugative transfer-related genes, thereby resulting into elevated horizontal transfer rate of plasmid-mediated ARG.	Nitrogen	106-114	ABL proto-oncogene 2, non-receptor tyrosine kinase	Homo sapiens	316-319
34537588-5	2021	The gas after reaction were analyzed by gas chromatography, and it was found that HCN was converted into CO2, N2 and NH3 by nanoparticles.	Nitrogen	110-112	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	82-85
34839261-7	2021	NF-kappaB/STT3A-regulated N-glycosylation was investigated by gene knockdown, chromatin immunoprecipitation, and promoter assay.	Nitrogen	26-27	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	10-15
34839261-11	2021	We found that inhibiting STT3A using N-linked glycosylation inhibitor-1 (NGI-1) impaired SARS-CoV-2 infectivity and that of its variants (Alpha (B.1.1.7) and Beta (B.1.351)).	Nitrogen	37-38	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	25-30
34669149-8	2021	Our results suggest that more nitrogen allocation to photosynthetic machinery has boosted Asat under cotton domestication.	Nitrogen	30-38	ATP binding cassette subfamily B member 7	Homo sapiens	90-94
34669149-9	2021	Improving the efficiency of nitrogen use in photosynthetic machinery might be future aim to enhance Asat of cotton.	Nitrogen	28-36	ATP binding cassette subfamily B member 7	Homo sapiens	100-104
34333442-5	2021	In addition to the adsorption effect, the XPS results also showed that N-containing groups on the NCA surface reduce the adsorbed Cr(VI) to the less toxic Cr(III).	Nitrogen	71-72	CEA cell adhesion molecule 6	Homo sapiens	98-101
34884793-1	2021	Multimodal spectroscopic imaging methods such as Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI), Fourier Transform Infrared spectroscopy (FT-IR) and Raman spectroscopy were used to monitor the changes in distribution and to determine semi quantitatively selected metabolites involved in nitrogen fixation in pea root nodules.	Nitrogen	322-330	RB binding protein 4, chromatin remodeling factor	Homo sapiens	126-129
34899694-15	2021	Together, these data suggest that partial CSF1R antagonism may render microglia more susceptible to reactive oxygen and nitrogen species.	Nitrogen	120-128	colony stimulating factor 1 receptor	Mus musculus	42-47
34831023-2	2021	FAM72A interacts with the uracil-DNA glycosylase UNG2 to prevent mutagenesis by eliminating uracil from DNA molecules through cleaving the N-glycosylic bond and initiating the base excision repair pathway, thus maintaining genome integrity.	Nitrogen	139-140	family with sequence similarity 72 member A	Homo sapiens	0-6
34730952-0	2021	Gas-Phase Nitrogen Doping of Monolithic TiO2 Nanoparticle-Based Aerogels for Efficient Visible Light-Driven Photocatalytic H2 Production.	Nitrogen	10-18	gastrin	Homo sapiens	0-3
34782916-7	2021	Ruminal ammonia-nitrogen concentration decreased linearly by 0.0137 mg dL-1 at each 10 g/kg of substitution and the time after feeding promoted the same effect (P < 0.001) decreased linearly by 0.6204 mg dL-1 at each hour after feeding.	Nitrogen	16-24	l(1)L1	Drosophila melanogaster	71-75
34782916-7	2021	Ruminal ammonia-nitrogen concentration decreased linearly by 0.0137 mg dL-1 at each 10 g/kg of substitution and the time after feeding promoted the same effect (P < 0.001) decreased linearly by 0.6204 mg dL-1 at each hour after feeding.	Nitrogen	16-24	l(1)L1	Drosophila melanogaster	204-208
34767596-5	2021	LS D40 appeared very fruitful in terms of soil moisture and nitrogen distribution, WUE, grain yield, and yield components than that of other LS levels.	Nitrogen	60-68	kinetochore scaffold 1	Homo sapiens	3-6
34618046-9	2021	Taken together, our results illustrate a mechanism by which CML38 interacts with PEPR2 to integrate LN and BR signals for coordinating root development to prevent quick depletion of N resources in Arabidopsis.	Nitrogen	182-183	calmodulin-like 38	Arabidopsis thaliana	60-65
34724064-4	2022	RESULTS: In Zeb2-cKO mice, the levels of plasma creatinine and blood urea nitrogen post-IRI were significantly lower than that in WT mice.	Nitrogen	74-82	zinc finger E-box binding homeobox 2	Mus musculus	12-16
34770852-1	2021	Carbonate MCO3 (M = Zn, Cd) can act as both Lewis acid and base to engage in a spodium bond with nitrogen-containing bases (HCN, NHCH2, and NH3) and a chalcogen bond with SeHX (X = F, Cl, OH, OCH3, NH2, and NHCH3), respectively.	Nitrogen	97-105	metastasis associated lung adenocarcinoma transcript 1	Homo sapiens	124-127
34778648-8	2021	When the atomic nitrogen gas generated by the PbDBD was sprayed onto the surface of the water phase and subsequently reacted as a plasma/liquid interfacial reaction, the nitrogen fixation rate increased by 7.26-fold compared to that when using the discharge without dielectric beads, and the ammonia production selectivity increased to 83.7%.	Nitrogen	16-24	gastrin	Homo sapiens	25-28
34778648-8	2021	When the atomic nitrogen gas generated by the PbDBD was sprayed onto the surface of the water phase and subsequently reacted as a plasma/liquid interfacial reaction, the nitrogen fixation rate increased by 7.26-fold compared to that when using the discharge without dielectric beads, and the ammonia production selectivity increased to 83.7%.	Nitrogen	170-178	gastrin	Homo sapiens	25-28
34768843-0	2021	The Overexpression of NUC Promotes Development and Increases Resistance to Nitrogen Deficiency in Arabidopsis thaliana.	Nitrogen	75-83	C2H2-like zinc finger protein	Arabidopsis thaliana	22-25
34768843-4	2021	NUC overexpression increased resistance to nitrogen (N) deficiency stress by increasing the chlorophyll content, suppressing anthocyanin accumulation, and increasing the biomass under N deficiency.	Nitrogen	43-51	C2H2-like zinc finger protein	Arabidopsis thaliana	0-3
34768843-4	2021	NUC overexpression increased resistance to nitrogen (N) deficiency stress by increasing the chlorophyll content, suppressing anthocyanin accumulation, and increasing the biomass under N deficiency.	Nitrogen	53-54	C2H2-like zinc finger protein	Arabidopsis thaliana	0-3
34768843-8	2021	Furthermore, we found that the N-responsive and lateral-root-related genes TGA1 and NRT2.4 had NUC-binding sites in their promoter regions and that their expression was upregulated by NUC under N deficiency.	Nitrogen	31-32	C2H2-like zinc finger protein	Arabidopsis thaliana	95-98
34768843-8	2021	Furthermore, we found that the N-responsive and lateral-root-related genes TGA1 and NRT2.4 had NUC-binding sites in their promoter regions and that their expression was upregulated by NUC under N deficiency.	Nitrogen	31-32	C2H2-like zinc finger protein	Arabidopsis thaliana	184-187
34721997-12	2021	Besides, N- and O-glycosylation analysis of S, N, and ORF3 protein reveals three known sites (25G+, 123N+, and 62V+) and three novel sites (144D+, 1009M+, and 1279L+) in the IBT/VN/2018 strain compared with the vaccine strains.	Nitrogen	9-10	ankyrin repeat, SAM and basic leucine zipper domain containing 1	Homo sapiens	54-58
34680700-6	2021	In Hemiptera, it is well established that AQP plays important roles in adjusting to physiological challenges including (1) regulating osmotic stress between the gut lumen and hemolymph after imbibing large quantities of a low nitrogen, sugar-rich liquid diet; (2) avoiding or preventing dehydration and desiccation; and (3) surviving at elevated temperatures.	Nitrogen	226-234	aquaporin AQPAe.a	Diaphorina citri	42-45
34609711-10	2022	Feature interpretation revealed that the aromatic ring system, heterocyclic nitrogen containing compounds and amines are important for cholinesterase inhibition.	Nitrogen	76-84	butyrylcholinesterase	Homo sapiens	135-149
34508780-1	2021	Cysteamine dioxygenase (ADO) plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis in humans by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate.	Nitrogen	165-166	2-aminoethanethiol dioxygenase	Homo sapiens	0-22
34508780-1	2021	Cysteamine dioxygenase (ADO) plays a vital role in regulating thiol metabolism and preserving oxygen homeostasis in humans by oxidizing the sulfur of cysteamine and N-terminal cysteine-containing proteins to their corresponding sulfinic acids using O2 as a cosubstrate.	Nitrogen	165-166	2-aminoethanethiol dioxygenase	Homo sapiens	24-27
34562451-1	2021	TMPRSS13, a member of the type II transmembrane serine protease (TTSP) family, harbors four N-linked glycosylation sites in its extracellular domain.	Nitrogen	92-93	transmembrane serine protease 13	Homo sapiens	0-8
34562451-3	2021	In this study, we examined the role of N-linked glycosylation in the proteolytic activity, autoactivation, and cellular localization of TMPRSS13.	Nitrogen	39-40	transmembrane serine protease 13	Homo sapiens	136-144
34562451-6	2021	Importantly, we showed that N-linked glycosylation was a critical determinant for subsequent phosphorylation of endogenous TMPRSS13.	Nitrogen	28-29	transmembrane serine protease 13	Homo sapiens	123-131
34378848-6	2021	The DEF+DPL group showed poorer motor performance, the loss of dopaminergic neurons, mitochondrial dysfunction, and neurodevelopment delay than the N+DPL group, and still didn"t recover to the Control level.	Nitrogen	148-149	prion like protein doppel	Mus musculus	150-153
34489534-0	2021	Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations.	Nitrogen	9-10	piezo type mechanosensitive ion channel component 1	Homo sapiens	76-82
34489534-3	2021	Here we show that N-linked glycosylation of two highly conserved asparagine residues in the "cap" region of mechanosensitive Piezo1 channels are necessary for the mature protein to reach the plasma membrane.	Nitrogen	18-19	piezo type mechanosensitive ion channel component 1	Homo sapiens	125-131
34489534-6	2021	Importantly, trafficking-defective Piezo1 variants linked to generalized lymphatic dysplasia and bicuspid aortic valve display reduced fully N-glycosylated Piezo1 protein.	Nitrogen	141-142	piezo type mechanosensitive ion channel component 1	Homo sapiens	35-41
34489534-6	2021	Importantly, trafficking-defective Piezo1 variants linked to generalized lymphatic dysplasia and bicuspid aortic valve display reduced fully N-glycosylated Piezo1 protein.	Nitrogen	141-142	piezo type mechanosensitive ion channel component 1	Homo sapiens	156-162
34121556-17	2021	The injection of anti-MPO IgG induced a significant elevation of Serum creatinine and blood urea nitrogen in serum, as well as urine blood, urine protein and urine leukocytes.	Nitrogen	97-105	myeloperoxidase	Rattus norvegicus	22-25
34075628-0	2021	Nitrogen-containing Bisphosphonates and Lipopolysaccharide Mutually Augment Inflammation via ATP- and IL-1beta-mediated Production of NETs.	Nitrogen	0-8	interleukin 1 alpha	Homo sapiens	102-110
34465681-9	2021	RESULTS: Creatinine, urea nitrogen, urine protein, and malondialdehyde (MDA) in the model group were significantly increased and inhibited by Echinacoside and alpha-Klotho treatment with Echinacoside dose-dependence.	Nitrogen	26-34	Klotho	Rattus norvegicus	165-171
34333551-2	2021	Here, we show that ELOngation of Very Long chain fatty acids protein 4 (ELOVL4), a rate-limiting enzyme in the biosynthesis of very-long polyunsaturated fatty acids (n-3, >=28 C), is expressed and transcriptionally repressed by the oncogene MYCN in neuroblastoma cells.	Nitrogen	166-167	MYCN proto-oncogene, bHLH transcription factor	Homo sapiens	241-245
34147727-8	2021	Nitrate decrease MDA by reducing the activities of superoxide dismutase, peroxidase, and catalase in root of the N-efficient genotype.	Nitrogen	113-114	peroxidase A2	Brassica napus	73-83
34486841-5	2021	This F-COP adsorbent with rich pi-stacking electrons contained abundant phenyl rings and imine (-C=N) groups throughout the molecular framework.	Nitrogen	99-100	caspase recruitment domain family member 16	Homo sapiens	7-10
34486841-7	2021	The F-COP was characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), nitrogen adsorption-desorption isotherms, and scanning electron microscopy (SEM).	Nitrogen	105-113	caspase recruitment domain family member 16	Homo sapiens	6-9
34229018-4	2021	The MAMA hydrolysates showed that the amount of neutral  (4Hex1)n  moiety is confirmed to be more bigger than that of acidic  (4HexA1)n   in SCP, whereas the amount of acidic  (4HexA1)n  moiety seems to be more bigger than that of neutral  (4Hex1)n  in SSP.	Nitrogen	64-65	exonuclease 1	Homo sapiens	59-63
34431737-8	2021	In the multiple linear regression analysis, serum urea nitrogen concentration, serum phosphorus concentration and blood ionised calcium concentration were independent variables predicting serum FGF-23 concentration.	Nitrogen	55-63	fibroblast growth factor 23	Felis catus	194-200
34448548-0	2021	Advances in Electrochemical Ammonia Synthesis Beyond the Use of Nitrogen Gas as a Source.	Nitrogen	64-72	gastrin	Homo sapiens	73-76
34466287-10	2021	The greatest N2O emissions and CH4 sink were recorded under the highest rate of N fertilization (100 kg N ha-1).	Nitrogen	80-81	plasma membrane ATPase	Triticum aestivum	106-110
34466287-10	2021	The greatest N2O emissions and CH4 sink were recorded under the highest rate of N fertilization (100 kg N ha-1).	Nitrogen	104-105	plasma membrane ATPase	Triticum aestivum	106-110
34466287-16	2021	The practice of applying biochar with N fertilizer at 100 kg ha-1 N resulted in increases in crop productivity and reduced N2O and CH4soil emissions under dryland cropping systems.	Nitrogen	66-67	plasma membrane ATPase	Triticum aestivum	61-65
34492829-4	2021	Subsequently, the Density Functional Theory (DFT) explained that CoP showed preference to bonding with the nitrogen atoms involved in the newly formed N N bond, and the Co-N bond dramatically enhanced the transfer of photo-generated electrons from the N-g-C3N4 nanosheets.	Nitrogen	107-115	caspase recruitment domain family member 16	Homo sapiens	65-68
34492829-4	2021	Subsequently, the Density Functional Theory (DFT) explained that CoP showed preference to bonding with the nitrogen atoms involved in the newly formed N N bond, and the Co-N bond dramatically enhanced the transfer of photo-generated electrons from the N-g-C3N4 nanosheets.	Nitrogen	252-253	caspase recruitment domain family member 16	Homo sapiens	65-68
34355770-5	2021	EC1118 ecm33 resulted in a reduction of fermentation duration in a defined medium with limiting and sufficient nitrogen (-20% and -13%, respectively) when shaken.	Nitrogen	111-119	Ecm33p	Saccharomyces cerevisiae S288C	7-12
34111283-4	2021	Reactive oxygen and nitrogen species (ROS/RNS), as well as redox signals, are key molecules involved at the crossroads of perceptions of different stress factors and regulation of both specific and general plant responses to biotic and abiotic stress.	Nitrogen	20-28	FAM20C golgi associated secretory pathway kinase	Homo sapiens	42-45
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	36-37	hypothetical protein	Arabidopsis thaliana	151-171
34327662-2	2021	Plants absorb nitrate-N or ammonium-N in the environment and undergo reduction reactions catalyzed by nitrate reductase (NR), nitrite reductase (NIR), glutamine synthetase (GS), and glutamine oxoglutarate aminotransferase (GOGAT) within plants.	Nitrogen	36-37	hypothetical protein	Arabidopsis thaliana	173-175
34360993-8	2021	Glycan analysis indicates that predominant glycoforms HexNAc2Hex8 and HexNAc2Hex11 are found at Asn119, Asn378, and Asn743, three of the canonical four N-glycosylation sites of human CP.	Nitrogen	152-153	ceruloplasmin	Homo sapiens	183-185
34335696-9	2021	Minor N-fractions in milk (MN) may be regulated by ELF2 and SLC7A11 (BTA 17), whilst ITPR2 and MYBPC1 (BTA 5), STIM2 (BTA 6), SGCD (BTA 7), SLC6A2 (BTA 18), TMCC2 and MFSD4A (BTA 16) are suggested to have an impact on various non-urea-N (NUN) fractions excreted via urine.	Nitrogen	235-236	inositol 1,4,5-trisphosphate receptor type 2	Bos taurus	85-90
34361179-5	2021	We elucidate whether controlling the distribution of bi-metal atoms into the C24N24 cavities can alter their catalytic activity toward CO2, NO2, H2, and N2 gas capture.	Nitrogen	153-155	gastrin	Homo sapiens	156-159
34138542-4	2021	We show for the first time that atomically dispersed Pt-N3C1 sites planted on nitrogen-doped carbon nanotubes (Pt1/N-CNTs), constructed via a stepwise polymerization-carbonization-electrostatic adsorption strategy, are highly active and selective toward Calpha-Cbeta bond cleavage in beta-O-4 model compounds under ambient conditions.	Nitrogen	78-86	zinc finger protein 77	Homo sapiens	111-114
34207099-1	2021	RNA methylation at the nitrogen sixth of adenosine (m6A, N6-methyladenosine) is the most abundant RNA modification which plays a crucial role in all RNA metabolic aspects.	Nitrogen	23-31	methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit	Homo sapiens	52-55
34178943-7	2021	We have newly identified systemic site-specific N-glycosylation alterations underlying T2D patients in the complement activation pathways, including decreased levels of N-glycopeptides from C1s, MASP1, and CFP proteins, and increased levels of N-glycopeptides from C2, C4, C4BPA, C4BPB, and CFH.	Nitrogen	48-49	MBL associated serine protease 1	Homo sapiens	195-200
34059939-8	2021	Deglycosylation assays with peptide N-glycosidase F showed that glycerol constant feed is associated with an N-glycosylated pattern of STEAP1.	Nitrogen	109-110	STEAP family member 1	Homo sapiens	135-141
34073083-0	2021	Novel Approach for the Synthesis of Chlorophosphazene Cycles with a Defined Size via Controlled Cyclization of Linear Oligodichlorophosphazenes (Cl(PCl2=N)n-PCl3)+(PCl6).	Nitrogen	153-155	metal response element binding transcription factor 2	Homo sapiens	148-152
34070741-2	2021	Vacant N-glycosylation sites (N220 and N229) of Kv3, voltage-gated K+ channels of high-firing neurons, deeply perturb channel activity in neuroblastoma (NB) cells.	Nitrogen	7-8	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	48-51
34070741-3	2021	Here we examined neuron development, localization, and activity of Kv3 channels in wildtype AB zebrafish and CRISPR/Cas9 engineered NB cells, due to perturbations in N-glycosylation processing of Kv3.1b.	Nitrogen	166-167	potassium voltage-gated channel subfamily A member 3	Rattus norvegicus	67-70
34513628-6	2021	Tramadol, as an opioid-like analgesic, is mainly metabolized into O-desmethyl tramadol (M1), by CYP2D6 and undergoes N-demethylation to M2, by CYP2B6 and CYP3A4.	Nitrogen	117-118	cytochrome P450, family 2, subfamily b, polypeptide 3	Rattus norvegicus	143-149
34163745-1	2021	Polymers containing Pd n L2n complexes as network junctions were obtained by reaction of poly(ethylene glycol)-linked N-donor ligands with Pd2+.	Nitrogen	118-119	PAF1 homolog, Paf1/RNA polymerase II complex component	Homo sapiens	139-142
34477522-8	2021	Chalcones, generally, are potential and more selective towards MAO-B inhibitions whereas pyrazolines derived from chalcones turned into selective towards MAO-A inhibitions due to maybe the presence of two nitrogen heteroatoms.	Nitrogen	205-213	monoamine oxidase A	Homo sapiens	154-159
35636643-4	2022	More importantly N-glucuronidation adduct was exclusively identified in all the hUGT1A4 mice, liver microsomes, and cultured primary hepatocytes, yet absent in the wide-type controls.	Nitrogen	17-18	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	80-87
35491865-0	2022	LINC00173 Promotes Wilms" Tumor Progression Through MGAT1-mediated MUC3A N-glycosylation.	Nitrogen	73-74	mucin 3A, cell surface associated	Homo sapiens	67-72
35491865-11	2022	Meanwhile, MGAT1 was verified to stabilize MUC3A protein by inducing N-glycosylation.	Nitrogen	69-70	mucin 3A, cell surface associated	Homo sapiens	43-48
35491865-12	2022	In summary, our study first discovered that LINC00173 promoted WT progression through MGAT1-mediated MUC3A N-glycosylation, giving new clues to further understanding the mechanism underlying WT progression.	Nitrogen	107-108	mucin 3A, cell surface associated	Homo sapiens	101-106
35043564-3	2022	propose that zVAD-fmk induces autophagy by inhibiting the N-glycanase NGLY1 rather than caspases.	Nitrogen	58-59	N-glycanase 1	Homo sapiens	70-75
35595070-6	2022	LF administration conferred significant dose-dependent renoprotective impact against GLY-induced RM as evidenced by the decreased renal/somatic index and the significant improvement in renal functions as confirmed by the significant increase in creatinine clearance, decrease in serum creatinine and blood urea nitrogen, and improvement in albuminuria and proteinuria.	Nitrogen	311-319	lactotransferrin	Rattus norvegicus	0-2
35629564-4	2022	After process optimization, the gas transport properties through the membranes were determined on the basis of pure gas permeation including CH4, CO2, O2, and N2 for two specific applications: biogas sweetening (CH4/CO2) and oxygen-enriched air (O2/N2).	Nitrogen	249-251	gastrin	Homo sapiens	32-35
35629564-4	2022	After process optimization, the gas transport properties through the membranes were determined on the basis of pure gas permeation including CH4, CO2, O2, and N2 for two specific applications: biogas sweetening (CH4/CO2) and oxygen-enriched air (O2/N2).	Nitrogen	249-251	gastrin	Homo sapiens	116-119
35526049-10	2022	Our results also showed that B3GNT5 protein was heavily N-glycosylated, which is critical for its protein stabilization.	Nitrogen	56-57	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	Homo sapiens	29-35
35333306-0	2022	The Mnn10/Anp1-dependent N-linked outer chain glycan is dispensable for Candida albicans cell wall integrity.	Nitrogen	25-26	Anp1p	Saccharomyces cerevisiae S288C	10-14
35077598-9	2022	As a result, N2 exhibited the lowest electronegative value and highest binding energy when docked with anti-inflammatory and anti-oxidant proteins CAT, COX, GP, IL-1, and MPO.	Nitrogen	13-15	catalase	Danio rerio	147-150
35507854-9	2022	Dietary supplementation of GAA and RPM also increased the meat color a* and b* values at 24 h. Finally, Treatment II increased total protein, and serum concentrations of albumin and creatinine, but decreased serum urea nitrogen concentrations, indicating improved protein efficiency.	Nitrogen	219-227	lysosomal alpha-glucosidase	Ovis aries	27-30
35486842-0	2022	Two SERPINC1 variants affecting N-glycosylation of Asn224 cause severe thrombophilia not detected by functional assays.	Nitrogen	32-33	serpin family C member 1	Homo sapiens	4-12
35486842-9	2022	Our study shows new elements involved in the regulation of N-glycosylation, a key post-translational modification that, according to our results affects folding, secretion and function, providing new evidence of the pathogenic consequence of an incorrect N-glycosylation of antithrombin.	Nitrogen	59-60	serpin family C member 1	Homo sapiens	274-286
35563717-5	2022	We found that a crude nonpolar extract of C. zofingiensis (ID name NAE_2022C), grown upon nitrogen deprivation, acts as a bioactive substance by inhibiting TNFR/NF-kappaB responses in human skin keratinocyte HaCaT cells.	Nitrogen	90-98	TNF receptor superfamily member 1A	Homo sapiens	156-160
35333511-3	2022	Herein, we develop an efficient catalytic material composed of a single-atom Ru-N4 site and Ru nanoparticles anchored on nitrogen-doped carbon (Ru1+NPs/N-C) through the coordination-pyrolysis strategy of the melamine formaldehyde resin.	Nitrogen	121-129	Scm like with four mbt domains 1	Homo sapiens	144-147
35092134-0	2022	N-glycosylation regulates MET processing and signaling.	Nitrogen	0-1	SAFB like transcription modulator	Homo sapiens	26-29
35092134-2	2022	MET contains 11 potential N-glycosylation sites, but the site-specific roles of these N-glycans have not been elucidated.	Nitrogen	26-27	SAFB like transcription modulator	Homo sapiens	0-3
35182768-6	2022	In the immunoprecipitate, glycopeptiforms corresponding to 11 out of the 12 potential N-glycosylation sites of integrin beta1, and to all nine potential glycosylation sites of integrin alpha2, were observed.	Nitrogen	86-87	integrin beta 1 (fibronectin receptor beta)	Mus musculus	111-125
34998749-0	2022	Pilot-scale demonstration of a novel process integrating Partial Nitritation with simultaneous Anammox, Denitrification and Sludge Fermentation (PN + ADSF) for nitrogen removal and sludge reduction.	Nitrogen	160-168	resistin	Homo sapiens	150-154
34998749-3	2022	In this process, PN was accomplished in a sequencing batch reactor (SBR) using the strategy of intermittent hydroxylamine addition, while ADSF coupling anammox and heterotrophic denitrification was conducted in an up-flow anaerobic sludge blanket reactor (UASB) to further remove nitrogen.	Nitrogen	280-288	resistin	Homo sapiens	138-142
34998749-7	2022	The pilot-scale demonstration confirmed that the PN + ADSF process is technically feasible for enhanced nitrogen removal and sludge reduction.	Nitrogen	104-112	resistin	Homo sapiens	54-58
35364374-1	2022	Se has beneficial effects on plants, through the stimulation of plant productivity, the reduction of abiotic stresses, and the improvement in N metabolism.	Nitrogen	142-143	squalene epoxidase	Homo sapiens	0-2
35364374-7	2022	We show the importance of sprayed Se in increasing the efficiency of N utilization, in addition to lessening environmental issues for aquaponics culture.	Nitrogen	69-70	squalene epoxidase	Homo sapiens	34-36
35407188-1	2022	Cu(im)2-derived Cu@N-C composites were used for the first time as efficient heterogeneous catalysts for one-pot 1,3-dipolar cycloaddition of terminal alkynes, aryl halides, and sodium azide to preparation of 1,4-disubstituted 1,2,3-triazoles with broad substrate scope and high yields.	Nitrogen	19-20	protection of telomeres 1	Homo sapiens	108-113
35286059-2	2022	Herein, the full hydrolysis process of the AB molecule on single Pt atom coordinated by two carbon atoms and one nitrogen atom (Pt1-C2N1) on nitrogen doped graphene is investigated using the density functional theory (DFT) method.	Nitrogen	113-121	zinc finger protein 77	Homo sapiens	128-131
35286059-2	2022	Herein, the full hydrolysis process of the AB molecule on single Pt atom coordinated by two carbon atoms and one nitrogen atom (Pt1-C2N1) on nitrogen doped graphene is investigated using the density functional theory (DFT) method.	Nitrogen	141-149	zinc finger protein 77	Homo sapiens	128-131
35286059-4	2022	In addition, 27 more types of M1-C2N1 (M represents transiton metal atom) and Pt1 supported on nitrogen-doped graphene with different local coordination environments (Pt1-CxNy, x and y are the number of carbon and nitrogen atoms that coordinated with the platinum atom) are considered to screen out potential single-atom catalysts for AB hydrolysis.	Nitrogen	95-103	zinc finger protein 77	Homo sapiens	78-81
35401119-10	2022	Collectively, our findings suggest that GPX1 might serve as a new target for the prevention of nitrogen radical-induced SGNs damage and hearing loss.	Nitrogen	95-103	glutathione peroxidase 1	Mus musculus	40-44
35090004-7	2022	Interestingly, when high-light stress and nitrogen starvation were combined, wild type and vtc2 plants exhibited photoinhibition to the same extent.	Nitrogen	42-50	GDP-L-galactose phosphorylase 1	Arabidopsis thaliana	91-95
35311117-4	2022	Here, we found N-glycosylation of PD-L1 in NPC cells and tissues.	Nitrogen	15-16	CD274 molecule	Homo sapiens	34-39
35311117-8	2022	Altogether, TGF-beta1 activated c-Jun/STT3A signaling pathway to promote N-glycosylation of PD-L1, thus further facilitating immune evasion and reducing the efficacy of cancer immunotherapy.	Nitrogen	73-74	STT3 oligosaccharyltransferase complex catalytic subunit A	Homo sapiens	38-43
35311117-8	2022	Altogether, TGF-beta1 activated c-Jun/STT3A signaling pathway to promote N-glycosylation of PD-L1, thus further facilitating immune evasion and reducing the efficacy of cancer immunotherapy.	Nitrogen	73-74	CD274 molecule	Homo sapiens	92-97
35147519-4	2022	It is shown the MoSe2-based nanomaterials have excellent selectivity to Nitrogen dioxide (NO2) according to gas sensing properties measurement.	Nitrogen	72-80	gastrin	Homo sapiens	108-111
35268610-1	2022	To establish a novel approach for VOCs resource utilization, coupled o-xylene oxidation and hematite reduction was investigated in this study in a high-temperature gas-solid reactor in the temperature range 300-700  C. As the o-xylene-containing inert gas (N2) stream traveled through the hematite particle bed, its reaction behavior was determined in programmed heating and constant temperature modes.	Nitrogen	257-259	gastrin	Homo sapiens	164-167
35308665-3	2022	The pathogenesis of sepsis is connected to inflammation and an excess of reactive oxygen and nitrogen species, which activate the pathogen-associated molecular pattern (PAMP)-pattern recognition receptor (PRR) and damage-associated molecular pattern (DAMP)-PRR signaling pathways.	Nitrogen	93-101	nectin cell adhesion molecule 1	Homo sapiens	205-208
35308665-3	2022	The pathogenesis of sepsis is connected to inflammation and an excess of reactive oxygen and nitrogen species, which activate the pathogen-associated molecular pattern (PAMP)-pattern recognition receptor (PRR) and damage-associated molecular pattern (DAMP)-PRR signaling pathways.	Nitrogen	93-101	nectin cell adhesion molecule 1	Homo sapiens	257-260
35048936-3	2022	Benefiting from the hierarchical structure, the exposure of more active sites and the doping effect of N and Fe, the N-Fe-Ni3S2@NiP2/NF material showed excellent electrocatalytic activity for the OER and UOR.	Nitrogen	103-104	BCL2 interacting protein 2	Homo sapiens	128-132
35075565-9	2022	The NiO-CaO5/SiO2-Al2O3 catalyst rendered stable reusability for five consecutive runs with liquid hydrocarbon yield within the range of 66-75% with n-(C15 + C17) selectivity of 64-72%.	Nitrogen	149-150	cytokine like 1	Homo sapiens	158-161
2556477-13	1989	N-linked glycosylation of the cytochrome b558 large subunit may not be essential for activation of the respiratory burst.	Nitrogen	0-1	mitochondrially encoded cytochrome b	Homo sapiens	30-42
2517036-2	1989	Originally designated as nif (= nitrogen fixation) or ntr (= nitrogen regulation) consensus promoter, it is now evident that this promoter occurs in many different bacterial species and is used not only for genes involved in nitrogen assimilation but also for genes determining many other unrelated metabolic functions.	Nitrogen	32-40	S100 calcium binding protein A9	Homo sapiens	25-28
2517036-2	1989	Originally designated as nif (= nitrogen fixation) or ntr (= nitrogen regulation) consensus promoter, it is now evident that this promoter occurs in many different bacterial species and is used not only for genes involved in nitrogen assimilation but also for genes determining many other unrelated metabolic functions.	Nitrogen	61-69	S100 calcium binding protein A9	Homo sapiens	25-28
2517036-2	1989	Originally designated as nif (= nitrogen fixation) or ntr (= nitrogen regulation) consensus promoter, it is now evident that this promoter occurs in many different bacterial species and is used not only for genes involved in nitrogen assimilation but also for genes determining many other unrelated metabolic functions.	Nitrogen	61-69	S100 calcium binding protein A9	Homo sapiens	25-28
2806548-6	1989	Complete N-linked deglycosylation of the neuronal dopamine transporter with the endoglycosidase, glycopeptidase-F, increased the electrophoretic mobility of the 62 kDa polypeptide to apparent Mr 48,000.	Nitrogen	9-10	solute carrier family 6 member 3	Homo sapiens	50-70
2514793-0	1989	N-glycosylation and in vitro enzymatic activity of human recombinant tissue plasminogen activator expressed in Chinese hamster ovary cells and a murine cell line.	Nitrogen	0-1	chromosome 20 open reading frame 181	Homo sapiens	69-97
2555029-4	1989	Alpha-MSH, the N-acetylated form of MSH, on the other hand, showed a highly significant inhibition of food intake in food-deprived rats with doses of 100 and 250 pmoles but no effect with the higher doses.	Nitrogen	15-16	proopiomelanocortin	Rattus norvegicus	0-9
2528451-7	1989	The protein sequence data reported here predict four N-linked glycosylation sites in the P40 molecule.	Nitrogen	53-54	interleukin 9	Mus musculus	89-92
2511902-0	1989	The binding of G-protein to rod outer segment phospholipids at the nitrogen-water interface.	Nitrogen	67-75	kinetochore associated 1	Homo sapiens	28-31
2475172-3	1989	The O2" hydroxyl groups of both rC and araC residues form intramolecular hydrogen bonds with N2 of the 5" guanine residue and replace the bridging water molecules in the deep groove of Z-DNA, which stabilize the guanine in the syn conformation.	Nitrogen	93-95	synemin	Homo sapiens	227-230
2775479-4	1989	3) Minimum structural requirements of a substrate of polyamine oxidase are two positively charged amino groups and an alkyl-substituent on one or both nitrogen atoms.	Nitrogen	151-159	polyamine oxidase	Homo sapiens	53-70
2658304-11	1989	The predicted gp64 protein contains seven potential N-linked glycosylation sites and hydrophobic N- and C-termini characteristic of signal and membrane anchor sequences found on envelope glycoproteins.	Nitrogen	52-53	gp64	Orgyia pseudotsugata multiple nucleopolyhedrovirus	14-18
3393306-11	1988	In addition, more CA3 pyramidal neurons showed mitochondrial alterations after exposure to nitrogen than in control or soman-containing saline.	Nitrogen	91-99	carbonic anhydrase 3	Rattus norvegicus	18-21
3384397-2	1988	This protein migrates Mr 45,000-70,000 dalton region with a broad singlet or doublet on SDS-PAGE, specifically binds to C3b and C4b, has an acidic pI around pH 4, is rich in proline in amino acid analysis, possesses both N-linked and O-linked oligosaccharides, generates iC3b by acting as a cofactor for I-mediated C3b cleavage, and does not disassemble the C3 convertases.	Nitrogen	221-222	complement C3	Homo sapiens	120-123
2832502-8	1988	Increases in N-POMC content of the pituitary lobe accompanied those of ACTH in animals 7, 10, 14 and 21 days after enucleation (P less than 0.01 compared with sham-treatment).	Nitrogen	13-14	proopiomelanocortin	Rattus norvegicus	15-19
3151020-13	1988	The nitrogen atom of the SCN- ion is 1.9 A from the zinc ion but shifted 1.3 A with respect to the hydroxyl ion in the native structure and at van der Waals" distance from the O gamma l atom of Thr-199.	Nitrogen	4-12	sorcin	Homo sapiens	25-28
3427034-2	1987	The object was to establish the conformation about the glycosidic linkages in the N-linked substructure GlcNAc(beta 1,6) [GlcNAc(beta 1,2)] Man(alpha)- by estimation of values for the appropriate glycosidic torsional angles.	Nitrogen	82-83	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	111-119
3427034-2	1987	The object was to establish the conformation about the glycosidic linkages in the N-linked substructure GlcNAc(beta 1,6) [GlcNAc(beta 1,2)] Man(alpha)- by estimation of values for the appropriate glycosidic torsional angles.	Nitrogen	82-83	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	129-137
2882693-0	1987	Role of dipeptidyl peptidase IV in uptake of peptide nitrogen from beta-casomorphin in rabbit renal BBMV.	Nitrogen	53-61	dipeptidyl peptidase 4	Oryctolagus cuniculus	8-31
3305626-3	1987	PRG (38.9 kDa) contains 40% carbohydrate consisting of 6 triantennary N-linked units and a single peptide chain of 231 amino acids, 75% of which = PRO + GLY + GLN.	Nitrogen	70-71	proline rich protein BstNI subfamily 3	Homo sapiens	0-3
3569163-3	1987	The cis-syn is formed in an ANTI-ANTI conformation about the N-glycosyl linkages and resembles the normal base-stacked configuration.	Nitrogen	29-30	synemin	Homo sapiens	8-11
3028776-4	1986	Sequence analysis of the cDNA clone revealed that the Ly-6E.1 protein consists of a 26-amino acid leader followed by a 108-residue, cysteine-rich, core protein with no N-linked glycosylation sites.	Nitrogen	27-28	lymphocyte antigen 6 complex, locus A	Mus musculus	54-61
3025621-3	1986	Steady-state levels of the DUR1,2 transcript responded to induction and nitrogen catabolite repression in the same way as urea amidolyase activity.	Nitrogen	72-80	bifunctional urea carboxylase/allophanate hydrolase	Saccharomyces cerevisiae S288C	27-33
3783794-5	1986	A conjugate of wheat germ agglutinin with ferritin, which binds noncovalently to cell surface glycoconjugates containing N-acetylneuraminyl and N-acetylglucosaminyl residues, was transported transcellularly in monomeric form, mainly through smooth-surfaced (plasmalemmal) vesicles and transendothelial channels.	Nitrogen	121-122	Fer2	Triticum aestivum	42-50
3517854-7	1986	Bovine IL-2 is unique among IL-2 homologs in that it has a single N-linked glycosylation site.	Nitrogen	66-67	interleukin 2	Bos taurus	7-11
3632200-10	1986	According to calculations, 0.9-1.0 g of bean protein/kg/day are necessary for nitrogen balance in male adults, and 1.2-1.3 g of protein bean would be the recommendation for a normal population.	Nitrogen	78-86	brain expressed associated with NEDD4 1	Homo sapiens	40-44
3510667-3	1986	The effects of N-linked glycosylation on the activation and secretion of lipoprotein lipase were studied in Ob17 cells.	Nitrogen	15-16	lipoprotein lipase	Mus musculus	73-91
4026285-7	1985	Analyses by thin-layer chromatography and mass spectrometry revealed that TDP-1 is polar and ninhydrin positive, exhibits fluorescence with UV irradiation, and is a nitrogen-containing component with an empirical formula of C15H20N2O4.	Nitrogen	165-173	tyrosyl-DNA phosphodiesterase 1	Gallus gallus	74-79
3894419-9	1985	BPI was detected, by indirect immunofluorescence, on the surface of PMN-associated E. coli within 5 min of incubation of E. coli with PMN both in room air and under N2.	Nitrogen	165-167	bactericidal permeability-increasing protein	Oryctolagus cuniculus	0-3
2988950-1	1985	The N-linked glycosylation of the murine receptor for transferrin has been investigated.	Nitrogen	4-5	transferrin	Mus musculus	54-65
3880572-11	1985	These results indicate that N-linked glycosylation has differential importance in the cell surface expression of class I molecules.	Nitrogen	28-29	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	Mus musculus	113-120
6441597-4	1984	This fraction represented TPA from which 85-90% of N-linked carbohydrate residues had been removed.	Nitrogen	51-52	chromosome 20 open reading frame 181	Homo sapiens	26-29
6510637-7	1984	A competitive inhibitor of FMO, methimazole, inhibited the N-hydroxylation of MAB by 65% in the case of MC-microsomes, and the residual activity was inhibited completely by anti-NADPH-cytochrome P-450 reductase (anti-fPT) antibody.	Nitrogen	59-60	cytochrome p450 oxidoreductase	Rattus norvegicus	178-210
6690691-1	1984	cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino] cyclohexanecarboxylic acid (N-Me-cis-CCCNU) was synthesized in five steps from cis-4-aminocyclohexanecarboxylic acid via an N-tosylated intermediate.	Nitrogen	87-88	suppressor of cytokine signaling 6	Mus musculus	0-5
6690691-1	1984	cis-4-[[[(2-Chloroethyl)nitrosoamino]carbonyl]methylamino] cyclohexanecarboxylic acid (N-Me-cis-CCCNU) was synthesized in five steps from cis-4-aminocyclohexanecarboxylic acid via an N-tosylated intermediate.	Nitrogen	87-88	suppressor of cytokine signaling 6	Mus musculus	138-143
6852052-6	1983	Acinar cells cultured in the presence of increasing concentrations of the N-glycosylation inhibitor tunicamycin synthesize 5-6 distinct precursor GP-2 species with apparent molecular weights decreasing from 73000-61000.	Nitrogen	74-75	glycoprotein 2	Rattus norvegicus	146-150
6304053-6	1983	Compared to other cholecystokinin receptor antagonists, CCK-27-32-NH2 is the most potent antagonist described to date, i.e. 30 times more potent than N2,O2-dibutyryl guanosine 3":5"-monophosphate.	Nitrogen	150-152	cholecystokinin	Cavia porcellus	56-59
6832094-6	1983	A high spin form of cytochrome P-450, isolated from the liver of PCB-treated rats, showed very high activity in N-hydroxylation of Trp-P-2, Glu-P-1 and 2-aminofluorene, although its activity was very low in benzo(a)pyrene hydroxylation.	Nitrogen	112-113	pyruvate carboxylase	Rattus norvegicus	65-68
7093196-8	1982	Under N2 or CO, phenylhydrazine reduces methemoglobin to deoxyhemoglobin or carbonmonoxyhemoglobin.	Nitrogen	6-8	hemoglobin subunit gamma 2	Homo sapiens	40-53
7035927-5	1981	The pso2-1 mutant was highly sensitive to the lethal effect of the bifunctional nitrogen mustard and was only slightly sensitive to the monofunctional one.	Nitrogen	80-88	DNA cross-link repair protein PSO2	Saccharomyces cerevisiae S288C	4-8
7301640-0	1981	Evidence that N-acetylation regulates the behavioral activity of alpha-MSH in the rat and human central nervous system.	Nitrogen	14-15	proopiomelanocortin	Rattus norvegicus	65-74
7301640-6	1981	N-acetylation of alpha-MSH may be an effective regulatory process for modulating the behavioral potency of the secretory product of alpha-MSH-containing pituitary cells and neurons.	Nitrogen	0-1	proopiomelanocortin	Rattus norvegicus	17-26
7301640-6	1981	N-acetylation of alpha-MSH may be an effective regulatory process for modulating the behavioral potency of the secretory product of alpha-MSH-containing pituitary cells and neurons.	Nitrogen	0-1	proopiomelanocortin	Rattus norvegicus	132-141
6913406-1	1981	The complex of elongation factor Tu with GTP (EF-Tu.GTP) reacts with N or epsilon -bromoacetyl-lys-tRNA ( or epsilon BrAcLys-tRNA) to form a functional covalently linked complex (XLTC).	Nitrogen	69-70	eukaryotic translation elongation factor, selenocysteine-specific	Drosophila melanogaster	46-51
6180051-5	1981	The effects of treatment of mouse L929 cells with pure IFN alpha or IFN beta on (2"-5") (A)n accumulation in the cell extracts were very similar both in respect to the dependence on the length of exposure of the cells to the IFNs and on IFN concentration.	Nitrogen	22-23	interferon alpha	Mus musculus	55-64
7275458-7	1981	From the 3rd week of treatment nitrogen loss was reduced in Gps 1 and 2 and virtually absent in Gp 3.	Nitrogen	31-39	GTP binding protein 1	Homo sapiens	60-71
6770893-5	1980	The Ca2+ and Mg2+ affinities may further be altered by replacing the ether oxygens by heterocyclic nitrogen atoms.	Nitrogen	99-107	carbonic anhydrase 2	Homo sapiens	4-7
6770893-6	1980	The compounds described are fluorescent Ca2+ indicators absorbing in the ultraviolet region; the very large spectral shifts observed on binding Ca2+ fit the prediction that complexation should hinder the conjugation of the nitrogen lone-pair electrons with the aromatic rings.	Nitrogen	223-231	carbonic anhydrase 2	Homo sapiens	40-43
6770893-6	1980	The compounds described are fluorescent Ca2+ indicators absorbing in the ultraviolet region; the very large spectral shifts observed on binding Ca2+ fit the prediction that complexation should hinder the conjugation of the nitrogen lone-pair electrons with the aromatic rings.	Nitrogen	223-231	carbonic anhydrase 2	Homo sapiens	144-147
6247646-6	1980	It is calculated that the N-atoms of the two PLP-substituted lysines must be at a distance less than or equal to 12 A. Analysing our and literature data, one may suppose that Lys-13 and Lys-87 are the most probable candidates for modification with PLP.	Nitrogen	26-27	proteolipid protein 1	Homo sapiens	248-251
6252740-5	1980	In case of matrix containing n-hexyl groups deoxyHb is oxidized by O2 to MetHb, instead of being oxygenated to HbO2.	Nitrogen	1-2	hemoglobin subunit gamma 2	Homo sapiens	73-78
7419336-4	1980	Mean daily Nitrogen loss was significantly lower (P &lt; 0.05) in Gps 3 and 4 than in Gps 1 and 2.	Nitrogen	11-19	GTP binding protein 1	Homo sapiens	86-97
497026-0	1979	Reactions of the trifunctional nitrogen mustard tris(2-chloroethyl)-amine (HN3) with human erythrocyte membranes in vitro.	Nitrogen	31-39	MT-RNR2 like 3 (pseudogene)	Homo sapiens	75-78
445220-3	1979	Despite the absence of an intramolecular hydrogen bond in the solid state, the N4-hydroxy substituent is syn to the ring N(3).	Nitrogen	79-80	synemin	Homo sapiens	105-108
363509-0	1978	[Effect of B polA1- exrA- and recA-gene mutations on the reparation of single-strand DNA breaks induced by N-nitrosomethylurea].	Nitrogen	86-87	RAD51 recombinase	Homo sapiens	30-34
205926-4	1978	A new view was constructed which suggests that the nitrogens of the DAT compounds were positioned better than those of the model compounds with regard to their binding sites.	Nitrogen	51-60	solute carrier family 6 member 3	Homo sapiens	68-71
149451-3	1978	n-Butanol-extracted ATPase is not inhibited by ruthenium red and is not activated by KCl.	Nitrogen	0-1	ATPase	Escherichia coli	20-26
71283-2	1977	The specificity of phosphorylcholine for PAP is attributable to the pentavalent nitrogen in phosphorylcholine, a feature that renders it resistant to hydrolysis by all other acid phosphatases.	Nitrogen	80-88	acid phosphatase 3	Homo sapiens	41-44
403755-4	1977	When P400 was infused in undernourished subjects without oral intake, balances of N, P, Mg, and Ca/70 kg of body weight per day were strongly negative (-4 g, -0.4 g, -6 mEq, and -0.2 g, respectively), whereas balances of K were about zero and those of Na and Cl were positive.	Nitrogen	82-83	E1A binding protein p400	Homo sapiens	5-9
599740-10	1977	The large change of n suggests that Ca2+ has a cooperative action in the healing-over process, or alternatively that the state of membrane lipids has some effect on the process.	Nitrogen	13-14	carbonic anhydrase 2	Homo sapiens	36-39
186698-6	1976	When grown on glucose and casamino acids growth could be stimulated by adenine and hypoxanthine nucleosides; these results suggest an impaired nitrogen metabolism in cya and crp mutants.	Nitrogen	143-151	catabolite gene activator protein	Escherichia coli	174-177
59652-0	1976	Determinant competition during the immune response to N-acyl derivatives of ox insulin in the Hartley guinea-pig.	Nitrogen	54-55	insulin	Cavia porcellus	79-86
164233-7	1975	Adrenal ferredoxin was the third subject in our studies of the intermediate states of proteins which appear after reduction of their active centres by means of electrons trapped in water-ethylene glycol mixtures at the temperature of liquid nitrogen [1, 2].	Nitrogen	241-249	ferredoxin 1	Homo sapiens	0-18
1234023-0	1975	Conformation of the common purine (beta) ribosides in solution: further evidence for a correlation between N-S state of the ribose moiety and syn-anti equilibrium.	Nitrogen	107-110	synemin	Homo sapiens	142-145
1171489-5	1975	It is concluded that the syndrome may be dependent on the formation of an N-substituted derivative of 5-HT which is at least partly deaminated by MAO-B.	Nitrogen	74-75	monoamine oxidase B	Rattus norvegicus	146-151
5439990-2	1970	Effects of daily ovine growth hormone injections on plasma metabolites and nitrogen-retention in fed lambs.	Nitrogen	75-83	somatotropin	Ovis aries	23-37
5968071-1	1966	I. Kinetics of the inhibition of the N-demethylation of ethylmorphine by 2-diethylaminoethyl 2,2-diphenylvalerate HC1 (SKF 525-A) and related compounds.	Nitrogen	37-38	CYCS pseudogene 39	Homo sapiens	114-117
13631194-8	1959	When diluted back to the volume of parent plasma, to a concentration of 0.2 microgram nitrogen per ml., thrombokinase can slowly activate prothrombin in the presence of oxalate, and without the addition of accessory factors.	Nitrogen	86-94	coagulation factor II, thrombin	Bos taurus	138-149
16653679-0	1941	EFFECT OF THE FORM OF THE AVAILABLE NITROGEN ON THE CALCIUM DEFICIENCY SYMPTOMS IN THE BEAN PLANT.	Nitrogen	36-44	brain expressed associated with NEDD4 1	Homo sapiens	87-91
33583911-2	2021	Congenital disorders of glycosylation (CDG) are multisystem diseases caused by mutations of a number of genes involved in N-glycosylation or O-glycosylation, and the most frequent form is PMM2-CDG (alias, CDG-Ia) resulting from biallelic mutations in PMM2 encoding phosphomannomutase-2 involved in N-glycosylation.	Nitrogen	122-123	phosphomannomutase 2	Homo sapiens	188-192
33583911-2	2021	Congenital disorders of glycosylation (CDG) are multisystem diseases caused by mutations of a number of genes involved in N-glycosylation or O-glycosylation, and the most frequent form is PMM2-CDG (alias, CDG-Ia) resulting from biallelic mutations in PMM2 encoding phosphomannomutase-2 involved in N-glycosylation.	Nitrogen	298-299	phosphomannomutase 2	Homo sapiens	188-192
33583911-4	2021	Whole exome sequencing identified biallelic pathogenic mutations of PMM2 (a novel c.34G>C:p.(Asp12His) of maternal origin and a recurrent c.310C>G:p.(Leu104Val) of paternal origin) (NM_000303.3), and N-glycosylation studies detected asialotransferrin and disialotransferrin characteristic of PMM2-CDG, in addition to normally glycosylated tetrasialotransferrin.	Nitrogen	182-183	phosphomannomutase 2	Homo sapiens	68-72
34038081-0	2021	Two-Dimensional Single-Atom Catalyst TM3(HAB)2 Monolayers for Electrocatalytic Dinitrogen Reduction Using Hierarchical High-Throughput Screening.	Nitrogen	79-89	tropomyosin 3	Homo sapiens	37-46
33983035-0	2021	Fe-Catalyzed Intramolecular B-H/C-H Dehydrogenative Coupling: Synthesis of Carborane-Fused Nitrogen Heterocycles.	Nitrogen	91-99	bleomycin hydrolase	Homo sapiens	28-31
33788378-1	2021	UMOD, an N-glycans-rich glycoprotein, is expressed in thick ascending limb of Henle"s loop where the epithelia need to adapt to gradient change of pH and ion concentration.	Nitrogen	9-10	uromodulin	Homo sapiens	0-4
33947045-6	2021	Intraperitoneal injection of USF1 PI polyamide significantly suppressed urinary albumin excretion and decreased serum urea nitrogen in the STZ-diabetic rats.	Nitrogen	123-131	upstream transcription factor 1	Rattus norvegicus	29-33
33859256-6	2021	Because tPA is a glycoprotein with three N-linked glycosylation sites, we hypothesized that tPA contains mannose 6-phosphate (M6P) and binds CI-MPR in a M6P-dependent manner.	Nitrogen	41-42	chromosome 20 open reading frame 181	Homo sapiens	8-11
33859256-6	2021	Because tPA is a glycoprotein with three N-linked glycosylation sites, we hypothesized that tPA contains mannose 6-phosphate (M6P) and binds CI-MPR in a M6P-dependent manner.	Nitrogen	41-42	chromosome 20 open reading frame 181	Homo sapiens	92-95
33917848-9	2021	Significant differences in nutrient intake were found between those at risk of malnourishment and those without risk, specifically in: protein, PUFA n-3, retinol, ascorbic acid, niacin equivalents, folic acid, magnesium, and potassium, respectively.	Nitrogen	3-4	pumilio RNA binding family member 3	Homo sapiens	144-148
32240040-7	2021	Loss of Tps2 leads to impaired autophagic flux and reduced ATG8 expression under nitrogen starvation.	Nitrogen	81-89	trehalose-phosphatase TPS2	Saccharomyces cerevisiae S288C	8-12
32240040-9	2021	Tps2 regulates nuclear translocation and activation of Rim15 kinase, a negative regulator of Ume6, by causing the dissociation of Rim15 from the 14-3-3 proteins Bmh1/2 under nitrogen starvation, suggesting that Rim15 mediates the function of Tps2 as a positive regulator of ATG8 induction.	Nitrogen	174-182	trehalose-phosphatase TPS2	Saccharomyces cerevisiae S288C	0-4
32240040-10	2021	Furthermore, Tps2 plays a crucial role in the dephosphorylation of Ser1061 and Thr1075 residues of Rim15, which is important for controlling the dissociation of Rim15 from Bmh1/2 under nitrogen starvation.	Nitrogen	185-193	trehalose-phosphatase TPS2	Saccharomyces cerevisiae S288C	13-17
33586916-9	2021	RESULTS: Animal under 7% O2  + 93% N2 condition for 3 hr showed the highest cognitive behavior impairment and upregulated HIF-1alpha and BACE1 mRNA in brains of offspring (p < .001).	Nitrogen	35-37	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	122-132
33586916-9	2021	RESULTS: Animal under 7% O2  + 93% N2 condition for 3 hr showed the highest cognitive behavior impairment and upregulated HIF-1alpha and BACE1 mRNA in brains of offspring (p < .001).	Nitrogen	35-37	beta-secretase 1	Rattus norvegicus	137-142
33841473-8	2021	Besides, activities of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) were increased, whereas the content of malondialdehyde (MDA) declined under foliar nitrogen application (especially NH4 +-N).	Nitrogen	171-179	SOD	Triticum aestivum	23-43
33722159-3	2021	Here, we conducted a multi-omic profiling of Atg9-dependent molecular landscapes during nitrogen starvation-induced autophagy, and identified 290 and 256 genes to be markedly regulated by ATG9 in transcriptional and translational levels, respectively.	Nitrogen	88-96	autophagy protein ATG9	Saccharomyces cerevisiae S288C	45-49
33722159-3	2021	Here, we conducted a multi-omic profiling of Atg9-dependent molecular landscapes during nitrogen starvation-induced autophagy, and identified 290 and 256 genes to be markedly regulated by ATG9 in transcriptional and translational levels, respectively.	Nitrogen	88-96	autophagy protein ATG9	Saccharomyces cerevisiae S288C	188-192
33678121-9	2021	Efficient transfer to phagophores depends on the sorting nexin heterodimer Snx4/Atg24-Atg20, which binds to Atg17, and relocates to the perinucleus following nitrogen starvation.	Nitrogen	158-166	RB1 inducible coiled-coil 1	Homo sapiens	108-113
33615322-1	2021	Nitrogen is one of the most significant non-native interstitial elements that is present in the structure of Fe.	Nitrogen	0-8	general transcription factor IIE subunit 1	Homo sapiens	109-111
33615322-4	2021	To clarify the temperature effect, nitridation was simulated in the range of 500-900 K, demonstrating that the adsorption of both N and H atoms into Fe was enhanced by thermal actuation.	Nitrogen	130-131	general transcription factor IIE subunit 1	Homo sapiens	149-151
33127052-0	2021	Enriched oxygen vacancies of Cu2O/SnS2/SnO2 heterostructure for enhanced photocatalytic reduction of CO2 by water and nitrogen fixation.	Nitrogen	118-126	strawberry notch homolog 2	Homo sapiens	39-42
33717018-0	2021	Nitrogen Fixing Azotobacter Species as Potential Soil Biological Enhancers for Crop Nutrition and Yield Stability.	Nitrogen	0-8	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	79-83
33485578-3	2021	In this study, a metal oxide hybrid with nitrogen-doped carbon dots (MFNCDs) that showed intrinsic peroxidase-like activity was synthesized and used as a catalyst instead of GOx to oxidize 3,3",5,5"-tetramethylbenzidine (TMB) to blue-emitting oxidized TMB (oxTMB) in the presence of hydrogen peroxide (H2O2).	Nitrogen	41-49	hydroxyacid oxidase 1	Homo sapiens	174-177
33730647-2	2021	This study fabricated Fe(III) loaded chitosan-biochar composite fibers (FBC-N and FBC-C) from paper mill sludge biochar produced under N2 (BC-N) and CO2 (BC-C) conditions at 600  C for adsorptive removal of phosphate from water.	Nitrogen	135-137	general transcription factor IIE subunit 1	Homo sapiens	22-29
33670614-5	2021	In vivo, the higher dose of the EP4 agonist led to an improved NTS phenotype, including a reduced tubular injury score and reduced neutrophil gelatinase-associated lipocalin (NGAL) and blood urea nitrogen (BUN) levels.	Nitrogen	196-204	prostaglandin E receptor 4 (subtype EP4)	Mus musculus	32-35
33347265-5	2021	We found that a single intravenous administration of siRNA (3 mg/kg BW) conjugated to GPR8 (GPR8:PCK-1siRNA(3 mg/kg BW) conjugate) in an optimized N/P ratio exploited as a therapeutic nanoformulation maintained glucose homeostasis for nearly 4 weeks in the T2DM mice.	Nitrogen	56-57	phosphoenolpyruvate carboxykinase 1, cytosolic	Mus musculus	97-102
33578954-2	2021	Aberrant N-glycosylation of integrin beta1 was documented to alter integrin beta1 expression, dimerization, and biological function.	Nitrogen	9-10	integrin subunit beta 1	Homo sapiens	28-42
33578954-2	2021	Aberrant N-glycosylation of integrin beta1 was documented to alter integrin beta1 expression, dimerization, and biological function.	Nitrogen	9-10	integrin subunit beta 1	Homo sapiens	67-81
33578954-3	2021	However, the biological function of site-specific N-glycosylation of integrin beta1 on extracellular vesicles is not fully understood.	Nitrogen	50-51	integrin subunit beta 1	Homo sapiens	69-83
33578954-4	2021	In this study, we mutated putative N-glycosylation sites in different domains of integrin beta1.	Nitrogen	35-36	integrin subunit beta 1	Homo sapiens	81-95
33578954-5	2021	Removal of the N-glycosylation sites on the I-like domain of integrin beta1 (termed the Delta4-6 beta1 mutant) suppressed focal adhesion kinase (FAK) signaling, cell migration, and adhesion compared with other beta1 mutants.	Nitrogen	15-16	integrin subunit beta 1	Homo sapiens	61-75
33578954-5	2021	Removal of the N-glycosylation sites on the I-like domain of integrin beta1 (termed the Delta4-6 beta1 mutant) suppressed focal adhesion kinase (FAK) signaling, cell migration, and adhesion compared with other beta1 mutants.	Nitrogen	15-16	immunoglobulin kappa variable 2D-30	Homo sapiens	70-75
33578954-8	2021	Our findings demonstrate the important roles of N-glycosylation of the I-like domain of integrin beta1.	Nitrogen	48-49	integrin subunit beta 1	Homo sapiens	88-102
33285464-1	2021	N-(2-18F-fluoropropionyl)-l-glutamate (18F-FPGLU), a new N-substituted 18F-labeling l-glutamate, is a potential amino acid tracer for oncology PET imaging with good tumor-to-background contrast in several tumor-bearing mice.	Nitrogen	0-1	thyroid stimulating hormone receptor	Mus musculus	143-146
33261832-4	2021	Under high N concentrations (>300 mg L-1), the Ace and Chao1 indexes increased, however, the Shannon index declined with increasing N concentration.	Nitrogen	11-12	angiotensin-converting enzyme	Sus scrofa	47-50
33404233-4	2021	As a result, it was subsequently employed as the emissive material of a single-layer LEC with configuration FTO/1/Ga/In, where studies reveal that it has a yellow color with CIE(x, y) = (0.33, 0.55), a luminance of 134 cd cm-2, and a turn-on voltage of 3.5 V. Protonation of the pendant pyridine nitrogen atoms of L1 afforded a second ionic complex [Pd(L1H)2](ClO4)2 (2) which is also emissive at room temperature with a lambdamax of 611 nm, resulting in an orange LEC with CIE(x, y) = (0.43, 0.53).	Nitrogen	296-304	C-C motif chemokine ligand 16	Homo sapiens	85-88
33520106-16	2021	Compared with normal rats, serum level of TNC in diabetic rats was significantly increased (P < 0.05), which was positively correlated with urea nitrogen and urinary creatinine (P < 0.05).	Nitrogen	145-153	tenascin C	Rattus norvegicus	42-45
33510871-4	2021	Based on the in-depth analysis of the binding mode, strong electron-withdrawing group on the C4 position of the imidazole ring was introduced to reduce the charge density of the nitrogen, which is beneficial in reducing the coordination bond between the imidazole nitrogen and heme iron in CYP11B1, as well as in reducing the adrenocortical suppression.	Nitrogen	178-186	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	290-297
33510871-4	2021	Based on the in-depth analysis of the binding mode, strong electron-withdrawing group on the C4 position of the imidazole ring was introduced to reduce the charge density of the nitrogen, which is beneficial in reducing the coordination bond between the imidazole nitrogen and heme iron in CYP11B1, as well as in reducing the adrenocortical suppression.	Nitrogen	264-272	cytochrome P450 family 11 subfamily B member 1	Homo sapiens	290-297
33177111-6	2021	CD55 had one N-linked glycosylation site in addition to a Ser/Thr-rich domain, which was expected to be heavily O-glycosylated.	Nitrogen	13-14	CD55 molecule (Cromer blood group)	Homo sapiens	0-4
32901097-6	2021	This study demonstrates molecular insights into hyperosmolarity effect on OSCC development and shows that NFAT5 transcription factor plays an important functional role in enhancing the oral cancer cell proliferation by inducing the EGFR translocation from the endoplasmic reticulum to the plasma membrane through increase the expression of DPAGT1, an essential enzyme for catalyzing the first committed step of N-linked protein glycosylation.	Nitrogen	106-107	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	340-346
33303737-4	2020	We further demonstrate that ManN and two N-glycosylation inhibitors stimulate EC proliferation via both JNK activation and the unfolded protein response caused by ER stress.	Nitrogen	31-32	mitogen-activated protein kinase 8	Mus musculus	104-107
33302425-4	2020	A potentiometric study was carried out to characterize the binding mode adopted by metal ions with TetraHPRG, showing the formation of complex species involving imidazole amide nitrogen atoms in metal binding.	Nitrogen	177-185	histidine rich glycoprotein	Homo sapiens	99-108
33263330-8	2020	Furthermore, a third successful implementation of the GlycoDelete technology focusing on murine IL-12B is shown to lead to N-glycosylation featuring an immature glycan in diffraction-quality crystals.	Nitrogen	123-124	interleukin 12b	Mus musculus	96-102
33166339-1	2020	The ST6Gal-I sialyltransferase, an enzyme that adds alpha2-6-linked sialic acids to N-glycosylated proteins, regulates multiple immunological processes.	Nitrogen	84-85	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	4-12
32768811-1	2020	In this paper, the widely used energetic material RDX had been modified with 2D high nitrogen polymer (TAGP).	Nitrogen	85-93	radixin	Homo sapiens	50-53
32537808-2	2020	Nitrogen-containing bisphosphonates, a current treatment for bone diseases, have been shown to block the growth of the T. brucei parasites by inhibiting farnesyl pyrophosphate synthase (FPPS); however, due to their poor pharmacokinetic properties they are not well suited for anti-parasitic therapy.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	186-190
32996649-9	2020	RESULTS: N-glycosylation enhanced the ability of CREBH to activate transcription and modulated the production of peroxisome proliferator-activated receptor alpha (PPARalpha) and stearoyl-CoA desaturase-1 (SCD-1) activity by affecting their promoter-driven transcription activity and protein interactions, leading to reduce lipid deposition and attenuate lipotoxicity.	Nitrogen	9-10	cAMP responsive element binding protein 3-like 3	Mus musculus	49-54
32996649-9	2020	RESULTS: N-glycosylation enhanced the ability of CREBH to activate transcription and modulated the production of peroxisome proliferator-activated receptor alpha (PPARalpha) and stearoyl-CoA desaturase-1 (SCD-1) activity by affecting their promoter-driven transcription activity and protein interactions, leading to reduce lipid deposition and attenuate lipotoxicity.	Nitrogen	9-10	stearoyl-Coenzyme A desaturase 1	Mus musculus	178-203
32996649-9	2020	RESULTS: N-glycosylation enhanced the ability of CREBH to activate transcription and modulated the production of peroxisome proliferator-activated receptor alpha (PPARalpha) and stearoyl-CoA desaturase-1 (SCD-1) activity by affecting their promoter-driven transcription activity and protein interactions, leading to reduce lipid deposition and attenuate lipotoxicity.	Nitrogen	9-10	stearoyl-Coenzyme A desaturase 1	Mus musculus	205-210
32996649-12	2020	Furthermore, increased N-glycosylation of CREBH, as achieved by overexpressing GnT-V could significantly improve liver lesion caused by unglycosylation of CREBH.	Nitrogen	23-24	cAMP responsive element binding protein 3-like 3	Mus musculus	42-47
32996649-12	2020	Furthermore, increased N-glycosylation of CREBH, as achieved by overexpressing GnT-V could significantly improve liver lesion caused by unglycosylation of CREBH.	Nitrogen	23-24	cAMP responsive element binding protein 3-like 3	Mus musculus	155-160
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	2-3	cAMP responsive element binding protein 3-like 3	Mus musculus	71-76
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	2-3	cAMP responsive element binding protein 3-like 3	Mus musculus	179-184
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	2-3	stearoyl-Coenzyme A desaturase 1	Mus musculus	272-277
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	9-10	cAMP responsive element binding protein 3-like 3	Mus musculus	71-76
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	9-10	cAMP responsive element binding protein 3-like 3	Mus musculus	179-184
32996649-13	2020	CONCLUSION: These findings have important implications for the role of CREBH N-glycosylation in proteolytic activation, and they provide the first link between N-glycosylation of CREBH, lipid metabolism, and lipotoxicity processes in the liver by modulating PPARalpha and SCD-1.	Nitrogen	9-10	stearoyl-Coenzyme A desaturase 1	Mus musculus	272-277
32996649-14	2020	These results provide novel insights into the N-glycosylation of CREBH as a therapeutic target for NAFLD.	Nitrogen	46-47	cAMP responsive element binding protein 3-like 3	Mus musculus	65-70
33059844-3	2020	The deletion of smt3 led to significant growth defects on the minimal media with different carbon and nitrogen sources, an obvious reduction (45.7 %) in aerial conidiation during optimal cultivation, and increasing sensitivities to metal ions, oxidation, cell wall perturbation, and the fungicide carbendazim during conidial germination and/or colony growth.	Nitrogen	102-110	SUMO family protein SMT3	Saccharomyces cerevisiae S288C	16-20
33039603-8	2020	Different physicochemical and biochemical parameters such as O-glycosylation and N-glycosylation, Hydrophobicity, GRAVY were identified within epitopic regions of S-protein.	Nitrogen	81-82	vitronectin	Homo sapiens	163-172
33239800-1	2020	The quantum spin properties of nitrogen-vacancy defects in diamond enable diverse applications in quantum computing and communications1.	Nitrogen	31-39	spindlin 1	Homo sapiens	12-16
32943465-3	2020	Eleven Fe-S cluster genes, including the NITROGEN FIXATION S (NIFS)-LIKE 1 (NFS1) and its interactor FRATAXIN (FH), when silenced in Nicotiana benthamiana, compromised nonhost resistance to Pseudomonas syringae pv.	Nitrogen	41-49	nitrogen fixation S (NIFS)-like 1	Arabidopsis thaliana	76-80
33081841-8	2020	The improved motor recovery in Hv1-/- mice was associated with decreased interleukin-1beta, reactive oxygen/ nitrogen species production and reduced neuronal loss.	Nitrogen	109-117	hepatitis virus (MHV-2) susceptibility	Mus musculus	31-34
32553951-3	2020	Like in many SRCR-containing proteins, the SRCR domain in hepsin has an N-glycosylation site, but its functional significance is unknown.	Nitrogen	72-73	hepsin	Homo sapiens	58-64
32553951-4	2020	In this study, we confirmed N-glycosylation at Asn112 in hepsin by glycosidase digestion and site-directed mutagenesis in human hepatoma cells.	Nitrogen	28-29	hepsin	Homo sapiens	57-63
33053347-5	2020	N-glycosylation blockade by Stt3a silencing is sufficient to inhibit non-exosomal vesicle secretion.	Nitrogen	0-1	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	Mus musculus	28-33
33036649-7	2020	RESULTS: PMM2-CDG patients had normal FXII levels (117%) but high proportions of a form lacking N-glycosylation at Asn414.	Nitrogen	96-97	phosphomannomutase 2	Homo sapiens	9-13
33036649-13	2020	PMM2-CDG have high levels of FXII lacking N-glycosylation at Asn414, but this glycoform displays similar activation than fully glycosylated, explaining the absence of angioedema in CDG.	Nitrogen	42-43	phosphomannomutase 2	Homo sapiens	0-4
33023272-0	2020	Crop Mass and N Status as Prerequisite Covariables for Unraveling Nitrogen Use Efficiency across Genotype-by-Environment-by-Management Scenarios: A Review.	Nitrogen	66-74	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	0-4
33023272-1	2020	Due to the asymptotic nature of the crop yield response curve to fertilizer N supply, the nitrogen use efficiency (NUE, yield per unit of fertilizer applied) of crops declines as the crop N nutrition becomes less limiting.	Nitrogen	90-98	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	36-40
32719549-0	2020	Suppression of G6PD induces the expression and bisecting GlcNAc-branched N-glycosylation of E-Cadherin to block epithelial-mesenchymal transition and lymphatic metastasis.	Nitrogen	60-61	glucose-6-phosphate dehydrogenase	Homo sapiens	15-19
32945502-0	2020	N-glycosylation and receptor tyrosine kinase signaling affect claudin-3 levels in colorectal cancer cells.	Nitrogen	0-1	claudin 3	Homo sapiens	62-71
32964251-1	2020	A reliable electrochemical biosensor is reported based on nitrogen-doped graphene nanosheets and gold nanoparticle (Au/N-G) nanocomposites for the event-specific detection of GM maize MIR162.	Nitrogen	58-66	MIR162	Zea mays	184-190
32964251-1	2020	A reliable electrochemical biosensor is reported based on nitrogen-doped graphene nanosheets and gold nanoparticle (Au/N-G) nanocomposites for the event-specific detection of GM maize MIR162.	Nitrogen	119-120	MIR162	Zea mays	184-190
32812958-0	2020	Lanthanide metal-organic frameworks with nitrogen functional sites for the highly selective and sensitive detection of NADPH.	Nitrogen	41-49	2,4-dienoyl-CoA reductase 1	Homo sapiens	119-124
32812958-2	2020	Due to the strong affinity between the bare phosphate group of NADPH and nitrogen functional sites, the highly selective and sensitive detection of NADPH was realized.	Nitrogen	73-81	2,4-dienoyl-CoA reductase 1	Homo sapiens	63-68
32812958-2	2020	Due to the strong affinity between the bare phosphate group of NADPH and nitrogen functional sites, the highly selective and sensitive detection of NADPH was realized.	Nitrogen	73-81	2,4-dienoyl-CoA reductase 1	Homo sapiens	148-153
32687357-1	2020	Although the N-H bond in peptide backbones is stronger than the C-H bond, hydrogen abstraction from the amide nitrogen is considered to be the initial step in the Calpha-C bond cleavage of peptide backbones by matrix-assisted laser desorption/ionization in-source decay (MALDI-ISD) when using an oxidizing matrix.	Nitrogen	110-118	carbonic anhydrase 2	Homo sapiens	163-171
32687357-4	2020	The electron abstraction occurs from either nitrogen or oxygen in the peptide backbone and induces the cleavage of both Calpha-C and N-H bonds in most amino acid residues, except for those on the N-terminal sides of Pro residues.	Nitrogen	44-52	carbonic anhydrase 2	Homo sapiens	120-128
32016676-6	2020	RESULTS: ELISA analysis showed that CXCL10 was associated with age, red blood cells, blood platelets, and blood urea nitrogen.	Nitrogen	117-125	C-X-C motif chemokine ligand 10	Homo sapiens	36-42
32739205-3	2020	Arginase 2 (ARG2) competes with nitric oxide synthase for the same substrate, L-arginine, and is implicated in the regulation of reactive nitrogen species.	Nitrogen	138-146	arginase type II	Mus musculus	0-10
32739205-3	2020	Arginase 2 (ARG2) competes with nitric oxide synthase for the same substrate, L-arginine, and is implicated in the regulation of reactive nitrogen species.	Nitrogen	138-146	arginase type II	Mus musculus	12-16
32405873-3	2020	Two nitrogen levels induced expression of some interesting regulating genes, such as USE1, STX1B_2_3, SEC23, SEC24, SEC61A, HSP A1_8, HSP20, and HSP90B/TRA1.	Nitrogen	4-12	unconventional SNARE in the ER 1	Homo sapiens	85-89
32405873-3	2020	Two nitrogen levels induced expression of some interesting regulating genes, such as USE1, STX1B_2_3, SEC23, SEC24, SEC61A, HSP A1_8, HSP20, and HSP90B/TRA1.	Nitrogen	4-12	SEC24 homolog B, COPII coat complex component	Homo sapiens	109-114
32405873-3	2020	Two nitrogen levels induced expression of some interesting regulating genes, such as USE1, STX1B_2_3, SEC23, SEC24, SEC61A, HSP A1_8, HSP20, and HSP90B/TRA1.	Nitrogen	4-12	SEC61 translocon subunit alpha 1	Homo sapiens	116-122
32405873-3	2020	Two nitrogen levels induced expression of some interesting regulating genes, such as USE1, STX1B_2_3, SEC23, SEC24, SEC61A, HSP A1_8, HSP20, and HSP90B/TRA1.	Nitrogen	4-12	heat shock protein 90 beta family member 1	Homo sapiens	152-156
32838939-5	2020	In a screen for N-glycosylated proteins that influence JCPyV pathology, we identified Adipocyte Plasma Membrane Associated Protein (APMAP) as a host cell modulator of JCPyV infection.	Nitrogen	16-17	adipocyte plasma membrane associated protein	Homo sapiens	86-130
32838939-5	2020	In a screen for N-glycosylated proteins that influence JCPyV pathology, we identified Adipocyte Plasma Membrane Associated Protein (APMAP) as a host cell modulator of JCPyV infection.	Nitrogen	16-17	adipocyte plasma membrane associated protein	Homo sapiens	132-137
32532816-0	2020	The RNA-binding protein Hfq assembles into foci-like structures in nitrogen starved Escherichia coli.	Nitrogen	67-75	RNA-binding protein	Escherichia coli	4-23
32787255-3	2020	Here, we propose a general rule for the design of nitride-based catalysts for ammonia synthesis, in which the nitrogen vacancy formation energy (ENV) dominates the catalytic performance.	Nitrogen	110-118	endogenous retrovirus group K member 20	Homo sapiens	145-148
32585103-7	2020	The results showed that PRMT7 has a preference of adding a methyl group to the omega-guanidino nitrogen Nn2 atom of the substrate Arg and that the second methylation reactions cannot occur, which are consistent with previous investigations.	Nitrogen	95-103	protein arginine methyltransferase 7	Homo sapiens	24-29
32781689-5	2020	DAL80 revealed higher transcriptional level when yeast cells were cultivated under nitrogen-limited conditions.	Nitrogen	83-91	Dal80p	Saccharomyces cerevisiae S288C	0-5
32764711-0	2020	Comprehensive N-glycosylation mapping of envelope glycoprotein from tick-borne encephalitis virus grown in human and tick cells.	Nitrogen	14-15	endogenous retrovirus group K member 20	Homo sapiens	41-62
32157382-13	2020	Previous work has unveiled that the Arg-N-end rule degradation pathway (Arg-N-degron pathway) mediates the degradation of PINK1, and thus fine-tune PINK1-dependent mitochondrial quality control pathway.	Nitrogen	40-41	PTEN induced kinase 1	Homo sapiens	122-127
32157382-13	2020	Previous work has unveiled that the Arg-N-end rule degradation pathway (Arg-N-degron pathway) mediates the degradation of PINK1, and thus fine-tune PINK1-dependent mitochondrial quality control pathway.	Nitrogen	40-41	PTEN induced kinase 1	Homo sapiens	148-153
32248283-1	2020	Rhizobium are nitrogen-fixing bacteria which possess the nif gene that codes for the nitrogenase enzyme involved in the reduction of atmospheric dinitrogen (N2) to ammonia.	Nitrogen	14-22	S100 calcium binding protein A9	Homo sapiens	57-60
32248283-1	2020	Rhizobium are nitrogen-fixing bacteria which possess the nif gene that codes for the nitrogenase enzyme involved in the reduction of atmospheric dinitrogen (N2) to ammonia.	Nitrogen	145-155	S100 calcium binding protein A9	Homo sapiens	57-60
32248283-1	2020	Rhizobium are nitrogen-fixing bacteria which possess the nif gene that codes for the nitrogenase enzyme involved in the reduction of atmospheric dinitrogen (N2) to ammonia.	Nitrogen	157-159	S100 calcium binding protein A9	Homo sapiens	57-60
31832669-6	2020	Furthermore, the divergent functions of rice OsNRT1.1A and OsNRT1.1B in regulating nitrogen utilization suggest that the function of NRT1.1 is still far from fully understood.	Nitrogen	83-91	nitrate transporter 1.1	Arabidopsis thaliana	47-53
31832669-7	2020	In this review, we focus on the most recent progress on molecular mechanisms of NRT1.1s in plants, with the aim to provide an evolved view for the versatile functions of NRT1.1 in nitrogen utilization in plants.	Nitrogen	180-188	nitrate transporter 1.1	Arabidopsis thaliana	80-86
32717805-8	2020	We show that ZmTK1 translocation to chloroplasts depends on a 72-amino-acid N-signal and its plastid localization is consistent with its ability to complement Arabidopsis tk1b mutants which are hypersensitive to ciprofloxacin (CIP), a genotoxic agent to organellar DNA.	Nitrogen	76-77	thymidine kinase	Zea mays	13-18
32708453-5	2020	PC contained higher amounts of omega-3 polyunsaturated fatty acids (n-3 PUFA) and thus the lowest n-6/n-3 ratio.	Nitrogen	5-6	pumilio RNA binding family member 3	Homo sapiens	72-76
32708453-5	2020	PC contained higher amounts of omega-3 polyunsaturated fatty acids (n-3 PUFA) and thus the lowest n-6/n-3 ratio.	Nitrogen	9-10	pumilio RNA binding family member 3	Homo sapiens	72-76
32039447-6	2020	We repeatedly found that N2a neuroblastoma cells and human neural stem cells grown in the presence of the cytokines developed large cytoplasmic clusters which stained positive for HS, the N-terminal of Abeta, Abeta, the C-terminal of APP, LC3 and LTR indicating accumulation of HS and APP/APP degradation products in enlarged autophagosomes/lysosomes.	Nitrogen	25-26	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	239-242
32234597-14	2020	RESULTS: TG-n2 and TG intervention ameliorated renal function as assessed by the levels of 24-h proteinuria, Cr, BUN, TC, TG, ALB and LDL-c.	Nitrogen	12-14	albumin	Rattus norvegicus	126-129
32665328-7	2020	Among the genes potentially promoting successful transitions to major nodulation lineages, the nod and nif clusters for nodulation and nitrogen fixation, respectively, were repeatedly acquired during each transition; the fix, dct, and phb clusters involved in energy conservation under micro-oxic conditions were present in the nonnodulating ancestors; and the secretion systems were acquired in lineage-specific patterns.	Nitrogen	135-143	S100 calcium binding protein A9	Homo sapiens	103-106
32656764-10	2021	Moreover, arsenate inhibited the activities of enzymes of the nitrogen metabolism (i.e. nitrate reductase, nitrite reductase, glutamine synthetase and glutamine 2-oxoglutarate aminotransferase) but increased the activity of glutamate dehydrogenase and NH4 + content.	Nitrogen	62-70	glutamine synthetase	Solanum lycopersicum	126-146
32614784-7	2021	The SARs analysis showed the structural difference including planar, quaternary nitrogen, and the peripheral functional groups at C-8, C-9, C-10, have strong effect on inhibition of TF activity, which provided effective methods to modify isoquinoline alkaloids for inhibiting TF activity.	Nitrogen	80-88	complement C9	Homo sapiens	135-138
32298759-2	2020	GLUT1 modification by N-linked glycosylation at a single asparagine residue (N45) appears to play multiple roles in the trafficking, stability and transport activity of this protein.	Nitrogen	22-23	solute carrier family 2 member 1	Homo sapiens	0-5
32298759-3	2020	Here we examine the role of complex N-glycosylation on GLUT1 function in renal epithelial cells by arresting this modification at the high-mannose stage with the mannosidase I inhibitor kifunensine.	Nitrogen	36-37	solute carrier family 2 member 1	Homo sapiens	55-60
32597395-3	2020	In this study, we demonstrated that the neuron-specific n-glycosylated protein NELL2 is important for neuronal polarization and axon growth using cultured rat embryonic hippocampal neurons.	Nitrogen	1-2	neural EGFL like 2	Rattus norvegicus	79-84
32513738-7	2020	Despite this difference in affinities of GID4 for Nt-IGLW vs. Nt-PGLW, we found that the GID4-mediated Pro/N-degron pathway of the yeast Saccharomyces cerevisiae can target an Nt-IGLW-bearing protein for rapid degradation.	Nitrogen	50-51	GID complex subunit 4 homolog	Homo sapiens	41-45
32639833-1	2020	The nitrogen-vacancy (NV) center is a potential atomic-scale spin sensor for electric field sensing.	Nitrogen	4-12	spindlin 1	Homo sapiens	61-65
32299730-0	2020	Discovery of delta opioid receptor full agonists lacking a basic nitrogen atom and their antidepressant-like effects.	Nitrogen	65-73	opioid receptor, delta 1	Mus musculus	13-34
32514747-0	2020	SAPK2 contributes to rice yield by modulating nitrogen metabolic processes under reproductive stage drought stress.	Nitrogen	46-54	serine/threonine-protein kinase SAPK2	Oryza sativa Japonica Group	0-5
32514747-4	2020	Subsequent analysis suggested that SAPK2 considerably influences the nitrogen, phosphorus, and potassium contents of rice grains.	Nitrogen	69-77	serine/threonine-protein kinase SAPK2	Oryza sativa Japonica Group	35-40
32514747-6	2020	CONCLUSION: These results suggest that SAPK2 could enhance grain production by regulating nitrogen utilization efficiency under RDS.	Nitrogen	90-98	serine/threonine-protein kinase SAPK2	Oryza sativa Japonica Group	39-44
32695607-20	2020	Furthermore, the results of animal tests demonstrated that local injection of CMCS/n (miR-21) promoted the early healing of osteoporotic bone defects.	Nitrogen	29-30	microRNA 21	Rattus norvegicus	86-92
32415589-0	2020	A cardiac troponin I photoelectrochemical immunosensor: nitrogen-doped carbon quantum dots-bismuth oxyiodide-flower-like SnO2.	Nitrogen	56-64	troponin I3, cardiac type	Homo sapiens	2-20
32393171-10	2020	Notably, we found a transcription factor ZmNLP6, a homolog of AtNLP7-a well-known regulator for N-response and root growth-generates several isoforms varied in capacities of activating downstream targets specifically after nitrate supply.	Nitrogen	0-1	NIN like protein 7	Arabidopsis thaliana	62-68
31883005-8	2020	Analysis of the intracellular state of tyrosinase showed a decrease in the mature tyrosinase form due to inhibition of N-linked oligosaccharide processing.	Nitrogen	119-120	tyrosinase	Homo sapiens	39-49
31883005-8	2020	Analysis of the intracellular state of tyrosinase showed a decrease in the mature tyrosinase form due to inhibition of N-linked oligosaccharide processing.	Nitrogen	119-120	tyrosinase	Homo sapiens	82-92
32066975-6	2020	IL-22-mediated host N-glycosylation is likely impaired in patients with ulcerative colitis (UC) and renders UC-HMA mice more susceptible to CDI.	Nitrogen	20-21	interleukin 22	Homo sapiens	0-5
32238930-8	2020	In the single-spin limit17 and using ultrapure nanoscale diamonds, it could allow quantum non-demolition read-out of the spin of nitrogen-vacancy centres at ambient conditions, deterministic entanglement between distant individual spins18 and matter-wave interferometry16,19,20.	Nitrogen	129-137	spindlin 1	Homo sapiens	14-18
32238930-8	2020	In the single-spin limit17 and using ultrapure nanoscale diamonds, it could allow quantum non-demolition read-out of the spin of nitrogen-vacancy centres at ambient conditions, deterministic entanglement between distant individual spins18 and matter-wave interferometry16,19,20.	Nitrogen	129-137	spindlin 1	Homo sapiens	121-125
32208424-2	2020	ICAM-1 is heavily N-glycosylated, and like other surface proteins, it is largely presumed that fully processed, complex N-glycoforms are dominant.	Nitrogen	18-19	intercellular adhesion molecule 1	Homo sapiens	0-6
32208424-2	2020	ICAM-1 is heavily N-glycosylated, and like other surface proteins, it is largely presumed that fully processed, complex N-glycoforms are dominant.	Nitrogen	120-121	intercellular adhesion molecule 1	Homo sapiens	0-6
32208424-5	2020	In this study, using the proximity ligation assay, we assessed the relative formation of high mannose, hybrid and complex alpha-2,6-sialyated N-glycoforms of ICAM-1 in human and mouse models of atherosclerosis, as well as in arteriovenous fistulas (AVF) of patients on hemodialysis.	Nitrogen	142-143	intercellular adhesion molecule 1	Homo sapiens	158-164
31791755-0	2020	The impact of ship emissions on nitrogen and sulfur deposition in China.	Nitrogen	32-40	inositol polyphosphate-5-phosphatase D	Homo sapiens	14-18
31791755-1	2020	A large amount of NOX and SO2 emitted from ships may elevate atmospheric N and S and eventually aggravate the deposition of N and S. The understanding of N and S deposition due to ship emissions is still limited, especially for China because it has a long coastline, busy shipping routes, and several large ports.	Nitrogen	18-19	inositol polyphosphate-5-phosphatase D	Homo sapiens	43-47
31791755-1	2020	A large amount of NOX and SO2 emitted from ships may elevate atmospheric N and S and eventually aggravate the deposition of N and S. The understanding of N and S deposition due to ship emissions is still limited, especially for China because it has a long coastline, busy shipping routes, and several large ports.	Nitrogen	73-74	inositol polyphosphate-5-phosphatase D	Homo sapiens	43-47
31791755-1	2020	A large amount of NOX and SO2 emitted from ships may elevate atmospheric N and S and eventually aggravate the deposition of N and S. The understanding of N and S deposition due to ship emissions is still limited, especially for China because it has a long coastline, busy shipping routes, and several large ports.	Nitrogen	73-74	inositol polyphosphate-5-phosphatase D	Homo sapiens	43-47
31791755-2	2020	To fill this gap, a comprehensive air quality model was employed in this study to quantify the contributions of ship emissions to N and S deposition on a national scale in China.	Nitrogen	130-131	inositol polyphosphate-5-phosphatase D	Homo sapiens	112-116
31791755-4	2020	The results indicate that ship emissions contributed significantly to the deposition of N and S, especially in coastal and offshore areas, where the largest ship contribution to both N and S deposition could exceed 15 kg ha-1 yr-1.	Nitrogen	88-89	inositol polyphosphate-5-phosphatase D	Homo sapiens	26-30
31791755-4	2020	The results indicate that ship emissions contributed significantly to the deposition of N and S, especially in coastal and offshore areas, where the largest ship contribution to both N and S deposition could exceed 15 kg ha-1 yr-1.	Nitrogen	88-89	inositol polyphosphate-5-phosphatase D	Homo sapiens	157-161
31791755-4	2020	The results indicate that ship emissions contributed significantly to the deposition of N and S, especially in coastal and offshore areas, where the largest ship contribution to both N and S deposition could exceed 15 kg ha-1 yr-1.	Nitrogen	183-184	inositol polyphosphate-5-phosphatase D	Homo sapiens	26-30
31791755-4	2020	The results indicate that ship emissions contributed significantly to the deposition of N and S, especially in coastal and offshore areas, where the largest ship contribution to both N and S deposition could exceed 15 kg ha-1 yr-1.	Nitrogen	183-184	inositol polyphosphate-5-phosphatase D	Homo sapiens	157-161
31791755-5	2020	For N deposition, ship emissions caused an increase in the total N deposition, not only in port areas and along shipping routes but also far inland, with evident seasonal variations.	Nitrogen	4-5	inositol polyphosphate-5-phosphatase D	Homo sapiens	18-22
31791755-5	2020	For N deposition, ship emissions caused an increase in the total N deposition, not only in port areas and along shipping routes but also far inland, with evident seasonal variations.	Nitrogen	65-66	inositol polyphosphate-5-phosphatase D	Homo sapiens	18-22
31900333-7	2020	Last, we observe that the N-terminal third of RFWD3 is only found in mammals, but not in other vertebrates or invertebrates.	Nitrogen	26-27	ring finger and WD repeat domain 3	Homo sapiens	46-51
31757705-1	2020	A novel fluorescence probe p-PBP for PA was synthesized based on a basic N atom as the electronic donor.	Nitrogen	73-74	phosphatidylethanolamine binding protein 1	Homo sapiens	29-32
32087368-5	2020	Furthermore, we find that both darkness and nitrogen depletion can induce the degradation of HY5 via 26S proteasome and the concomitant disassociation of HDA9 from ATG5 and ATG8e loci to relieve their repression, thereby activating autophagy.	Nitrogen	44-52	histone deacetylase 9	Homo sapiens	154-158
32087368-5	2020	Furthermore, we find that both darkness and nitrogen depletion can induce the degradation of HY5 via 26S proteasome and the concomitant disassociation of HDA9 from ATG5 and ATG8e loci to relieve their repression, thereby activating autophagy.	Nitrogen	44-52	microtubule associated protein 1 light chain 3 alpha	Homo sapiens	173-178
31865156-4	2020	The aprA and chiA-related bacteria converted amino acid nitrogen to ammonium, and ammonium to hydrolysable unknown nitrogen, while amoA and HAO-related bacteria converted amine and amino sugar nitrogen to ammonium.	Nitrogen	56-64	chitinase acidic	Sus scrofa	13-17
31865156-4	2020	The aprA and chiA-related bacteria converted amino acid nitrogen to ammonium, and ammonium to hydrolysable unknown nitrogen, while amoA and HAO-related bacteria converted amine and amino sugar nitrogen to ammonium.	Nitrogen	115-123	chitinase acidic	Sus scrofa	13-17
31865156-4	2020	The aprA and chiA-related bacteria converted amino acid nitrogen to ammonium, and ammonium to hydrolysable unknown nitrogen, while amoA and HAO-related bacteria converted amine and amino sugar nitrogen to ammonium.	Nitrogen	115-123	chitinase acidic	Sus scrofa	13-17
31902824-9	2020	A pulldown assay revealed that CD81 was conjugated with a K63- and K29-linked poly-ubiquitin chain before its degradation, and the poly-ubiquitination site was Lys8 at the N-terminal intracellular domain of CD81.	Nitrogen	172-173	CD81 molecule	Homo sapiens	31-35
31999132-3	2020	Use of O-methyl-N-tosyl carbamate (R3 = CO2Me) as the nitrogen nucleophile followed by treatment of the product with trifluoroacetic acid leads to the syn-oxyaminated product in up to 77% yield.	Nitrogen	54-62	synemin	Homo sapiens	151-154
31899794-0	2020	Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia.	Nitrogen	38-39	hepcidin antimicrobial peptide	Mus musculus	64-72
31951383-6	2020	Legumain cannot cleave after glycosylated Asn residues, which ena-bled robust identification and orthogonal validation of N-glycosylation sites based on alternating sequential sample treatment with legumain and PNGaseF and vice versa.	Nitrogen	122-123	legumain	Homo sapiens	0-8
31968163-1	2020	Nickel (Ni) catalysts supported on mesoporous graphitic carbon nitride (mpg-C3N4) were synthesized through simple impregnation method with air and nitrogen calcination atmosphere for CO methanation.	Nitrogen	147-155	N-methylpurine DNA glycosylase	Homo sapiens	72-75
31952439-4	2020	Without using any cocatalysts, the eBP NFs catalyze nitrogen fixation at a rate of 2.37 mmol h-1 g-1 under visible-light irradiation.	Nitrogen	52-60	EBP cholestenol delta-isomerase	Homo sapiens	35-38
31952439-5	2020	The photocatalytic process is analyzed by photoelectrochemical and transient absorption measurements, which disclose electron transfer from eBP NFs to N2 for subsequent hydrogenation.	Nitrogen	151-153	EBP cholestenol delta-isomerase	Homo sapiens	140-143
31952439-6	2020	Besides the facile and scalable synthesis method, eBP NFs with a high photocatalytic nitrogen fixation efficiency have great potential in ammonia production.	Nitrogen	85-93	EBP cholestenol delta-isomerase	Homo sapiens	50-53
32029834-1	2020	In this article, halloysite nanoclay (Hal) was used as porogen for the synthesis of nitrogen doped porous carbon material with high specific surface area and pore volume.	Nitrogen	84-92	histidine ammonia-lyase	Homo sapiens	38-41
31866442-4	2020	The SLC1A5 variant has an N-terminal targeting signal for mitochondrial localization.	Nitrogen	26-27	solute carrier family 1 member 5	Homo sapiens	4-10
31843715-9	2020	SAP-drug (anti-TNF-alpha/HGF in SAP hydrogel) treatment reduced the level of serum creatinine (Scr), blood urea nitrogen (BUN), tubular apoptosis, renal inflammatory factors, and macrophage infiltration compared to Free-drug (anti-TNF-alpha/HGF in solution) or SAP alone.	Nitrogen	112-120	hepatocyte growth factor	Mus musculus	25-28
31704455-1	2020	We report a novel chiral interface based on polysaccharides that was integrated via an amidation reaction between the COOH of sodium alginate and the NH2 of chitosan to form a chiral selector (SA-CS) with three dimensional N-doped graphene-CNT (NGC) as the substrate material.	Nitrogen	150-151	sacsin molecular chaperone	Homo sapiens	193-198
31756397-7	2020	The changes in 1/CV2 and VMR values correctly reflect experimental modifications of N, Pr and Q at Sc-CA1 synapses.	Nitrogen	84-85	BMP-binding endothelial regulator	Mus musculus	17-20
31756397-10	2020	CONCLUSION: Combining the 1/CV2 with the VMR allows for a reliable prediction of the relative contribution of changes in N, Pr and Q to synaptic plasticity.	Nitrogen	2-3	BMP-binding endothelial regulator	Mus musculus	28-31
31581317-2	2020	A wheat nitrate-inducible NAC transcription factor, TaNAC2 plays a critical role in promoting crop growth and nitrogen use efficiency and now we show its role in seed vigour.	Nitrogen	110-118	NAC domain-containing protein 2	Triticum aestivum	52-58
31639410-0	2020	Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.	Nitrogen	0-8	FBJ osteosarcoma oncogene B	Mus musculus	84-88
31639410-3	2020	In nitrogen-mustard-exposed mouse skin, we found p-ERK activation increased Fra-1 and FosB.	Nitrogen	3-11	FBJ osteosarcoma oncogene B	Mus musculus	86-90
31937660-0	2020	CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention.	Nitrogen	36-37	CCCTC-binding factor	Homo sapiens	0-4
31937660-2	2020	Here, we demonstrate that a 79-aa region within the CTCF N terminus is essential for cohesin positioning at CTCF binding sites and chromatin loop formation.	Nitrogen	57-58	CCCTC-binding factor	Homo sapiens	52-56
31937660-2	2020	Here, we demonstrate that a 79-aa region within the CTCF N terminus is essential for cohesin positioning at CTCF binding sites and chromatin loop formation.	Nitrogen	57-58	CCCTC-binding factor	Homo sapiens	108-112
31937660-3	2020	However, the N terminus of CTCF fused to artificial zinc fingers was not sufficient to redirect cohesin to non-CTCF binding sites, indicating a lack of an autonomously functioning domain in CTCF responsible for cohesin positioning.	Nitrogen	13-14	CCCTC-binding factor	Homo sapiens	27-31
31937660-5	2020	Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin retention.	Nitrogen	80-81	CCCTC-binding factor	Homo sapiens	13-17
31937660-5	2020	Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin retention.	Nitrogen	80-81	CCCTC-binding factor	Homo sapiens	94-98
31937660-5	2020	Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin retention.	Nitrogen	80-81	CCCTC-binding factor	Homo sapiens	94-98
31937660-5	2020	Furthermore, CTCF-BORIS chimeric constructs provided evidence that, besides the N terminus of CTCF, the first two CTCF zinc fingers, and likely the 3D geometry of CTCF-DNA complexes, are also involved in cohesin retention.	Nitrogen	80-81	CCCTC-binding factor	Homo sapiens	94-98
31968674-2	2020	Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N-terminal asparagine amidohydrolase 1 (NTAN1) into aspartate.	Nitrogen	37-38	N-terminal asparagine amidase	Homo sapiens	119-157
31968674-2	2020	Especially, degradation signaling of N-terminal asparagine (Nt-Asn) in eukaryotes is initiated from its deamidation by N-terminal asparagine amidohydrolase 1 (NTAN1) into aspartate.	Nitrogen	37-38	N-terminal asparagine amidase	Homo sapiens	159-164
31694953-11	2020	In this study, the nuclear targeting and BFRF1-interacting domains were found within the N-terminus of BFRF2.	Nitrogen	89-90	nuclear egress membrane protein	Human gammaherpesvirus 4	41-46
31931858-11	2020	When subjected to both Gli-i and N-Shh treatment, NSCLC cell lines continued to demonstrate decreased Gli transcriptional activity.	Nitrogen	33-34	GLI family zinc finger 1	Homo sapiens	102-105
31936901-5	2020	Here, we present a quantitative characterization of the effect of the T42A mutation on the binding of the N-terminal SH2 domain of SHP2 with a peptide mimicking Gab2, a fundamental interaction that triggers the activation of the phosphatase in the cellular environment.	Nitrogen	106-107	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	131-135
31901076-0	2020	Erratum for Research Article "Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-beta" by J. Li, M. Ritelli, C. S. Ma, G. Rao, T. Habib, E. Corvilain, S. Bougarn, S. Cypowyj, L. Grodecka, R. Levy, V. Beziat, L. Shang, K. Payne, D. T. Avery, M. Migaud, S. Boucherit, S. Boughorbel, A. Guennoun, M. Chrabieh, F. Rapaport, B. Bigio, Y. Itan, B. Boisson, V. Cormier-Daire, D. Syx, F. Malfait, N.	Nitrogen	120-121	interleukin 17A	Homo sapiens	147-153
31815737-5	2020	They also showed that MAGT1 is required for N-glycosylation of key T cell and NK cell receptors that can account for some of the clinical features.	Nitrogen	44-45	magnesium transporter 1	Homo sapiens	22-27
31815737-6	2020	Notably, transfection of the affected lymphocytes with MAGT1 mRNA restored both N-glycosylation and receptor function.	Nitrogen	0-1	magnesium transporter 1	Homo sapiens	55-60
31635807-2	2020	We previously showed that dantrolene, a specific agent for the treatment of malignant hyperthermia, inhibits Ca2+ leakage from the RyR2 by correcting the defective inter-domain interaction between the N-terminal (1-619 amino acids) and central (2000-2500 amino acids) domains of the RyR2 and allosterically enhancing the binding affinity of calmodulin to the RyR2 in diseased hearts.	Nitrogen	201-202	ryanodine receptor 2, cardiac	Mus musculus	131-135
31571199-7	2020	Immunoprecipitation confirmed the presence of anti-IFI16 IgG antibodies and these preferentially recognized epitopes outside the N-terminus of the protein.	Nitrogen	129-130	interferon gamma inducible protein 16	Homo sapiens	51-56
31840614-5	2020	METHOD: We genetically engineered beta2-Adrenergic receptor to put an HA tag at the extracellular N-terminus and GFP Tag at the intracellular C-terminus.	Nitrogen	98-99	adrenoceptor beta 2	Homo sapiens	34-59
31494931-7	2020	Furthermore, MGAT1 promotes complex N-glycosylation of glucose transporter 1 (Glut1) and increases Glut1 protein levels.	Nitrogen	36-37	solute carrier family 2 member 1	Homo sapiens	55-76
31494931-7	2020	Furthermore, MGAT1 promotes complex N-glycosylation of glucose transporter 1 (Glut1) and increases Glut1 protein levels.	Nitrogen	36-37	solute carrier family 2 member 1	Homo sapiens	78-83
31781989-4	2020	Here we demonstrate the important role of the flexible N-terminal region of the MDM2 protein in the binding with small molecule compounds, which contributes to the transition from three point binding to four point binding during the development of new anticancer agents.	Nitrogen	55-56	MDM2 proto-oncogene	Homo sapiens	80-84
31792442-5	2020	HSP70 recognizes the amino (N)-terminal flexible region, as well as the glutathione S-transferase domain of AIMP2-DX2, via its substrate-binding domain, thus blocking the Siah1-dependent ubiquitination of AIMP2-DX2.	Nitrogen	28-29	heat shock protein family A (Hsp70) member 4	Homo sapiens	0-5
32526762-7	2020	RESULTS: The results suggest that mTOR inhibition significantly attenuated the induction of fibrosis, with restored serum creatinine and blood urea nitrogen levels.	Nitrogen	148-156	mechanistic target of rapamycin kinase	Rattus norvegicus	34-38
31641075-4	2020	To demonstrate that SDG8-mediated regulation of RNA isoform expression is functionally relevant, we examined a putative regulatory gene, CONSTANS, CO-like and TOC1 101 (CCT101), whose nitrogen-responsive isoform-specific RNA expression is mediated by SDG8.	Nitrogen	184-192	B-box type zinc finger protein with CCT domain-containing protein	Arabidopsis thaliana	137-167
31886770-5	2019	The flexible ATPase lobe, composed of helicase subunit Sth1, Arp7, Arp9 and Rtt102, is anchored to this core by the N-terminus of Sth1.	Nitrogen	116-117	Rtt102p	Saccharomyces cerevisiae S288C	76-82
31710063-1	2019	The linear synthesis of the N-terminal domain of mISG15 has been developed which enables the synthesis of full-length mISG15 and the activity-based probe Rho-mISG15-PA via native chemical ligation.	Nitrogen	28-29	ISG15 ubiquitin-like modifier	Mus musculus	49-55
31710063-1	2019	The linear synthesis of the N-terminal domain of mISG15 has been developed which enables the synthesis of full-length mISG15 and the activity-based probe Rho-mISG15-PA via native chemical ligation.	Nitrogen	28-29	ISG15 ubiquitin-like modifier	Mus musculus	118-124
31710063-1	2019	The linear synthesis of the N-terminal domain of mISG15 has been developed which enables the synthesis of full-length mISG15 and the activity-based probe Rho-mISG15-PA via native chemical ligation.	Nitrogen	28-29	ISG15 ubiquitin-like modifier	Mus musculus	118-124
31861875-9	2019	Binding assays with the deletion mutants of Galectin-8, comprising either of the two carbohydrate recognition domains (CRD), revealed that K-Ras4B only interacts with the N-CRD, but not with the C-CRD.	Nitrogen	171-172	KRAS proto-oncogene, GTPase	Homo sapiens	139-146
31861875-11	2019	Our results demonstrate that Galectin-8 is a new binding partner for K-Ras4B and it interacts via the N-CRD with the farnesylated PBD of K-Ras, thereby modulating the K-Ras effector pathways as well as cell proliferation and migration.	Nitrogen	102-103	KRAS proto-oncogene, GTPase	Homo sapiens	69-76
31861875-11	2019	Our results demonstrate that Galectin-8 is a new binding partner for K-Ras4B and it interacts via the N-CRD with the farnesylated PBD of K-Ras, thereby modulating the K-Ras effector pathways as well as cell proliferation and migration.	Nitrogen	102-103	KRAS proto-oncogene, GTPase	Homo sapiens	69-74
31861875-11	2019	Our results demonstrate that Galectin-8 is a new binding partner for K-Ras4B and it interacts via the N-CRD with the farnesylated PBD of K-Ras, thereby modulating the K-Ras effector pathways as well as cell proliferation and migration.	Nitrogen	102-103	KRAS proto-oncogene, GTPase	Homo sapiens	137-142
31625659-4	2019	A combination of biophysical experiments further suggested that Dectin-1 recognizes aromatic amino acids adjacent to the  N -terminal asparagine residue at the glycosylation site as well as core fucose residue.	Nitrogen	122-123	C-type lectin domain containing 7A	Sus scrofa	64-72
31625659-5	2019	Thus, Dectin-1 appears to be the first lectin-like molecule involved in the hetero-valent and specific recognition of characteristic  N -glycans on antibodies.	Nitrogen	134-135	C-type lectin domain containing 7A	Sus scrofa	6-14
31888240-4	2019	The single-nucleotide polymorphism (SNP) of N-acetylgalactosaminyltransferase14 (GALNT14) has been proven to predict the progression-free survival (PFS), overall survival (OS) and response to chemotherapy in various types of gastrointestinal (GI) cancers.	Nitrogen	37-38	polypeptide N-acetylgalactosaminyltransferase 14	Homo sapiens	81-88
31604529-0	2019	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on beta-adrenoceptors.	Nitrogen	4-5	phosphatidylethanolamine binding protein 1	Homo sapiens	67-71
31604529-5	2019	Co-immunoprecipitation assays and pull-down assays revealed subtype specificity of RKIP for the cardiac GRK isoforms GRK2 and GRK3 - not GRK5 - as well as several RKIP binding sites within their N-termini (GRK21-185 and GRK31-185).	Nitrogen	195-196	phosphatidylethanolamine binding protein 1	Homo sapiens	83-87
31604529-6	2019	Overexpression of these N-termini prevented beta2-AR phosphorylation and internalization, subsequently increased receptor signaling in HEK293 cells and cardiomyocyte contractility.	Nitrogen	24-25	adrenoceptor beta 2	Homo sapiens	44-52
31604529-7	2019	Co-immunoprecipitation assays of beta2-AR with these N-terminal GRK fragments revealed a direct interaction suggesting a steric interference of the fragments with the functional GRK-receptor interaction.	Nitrogen	53-54	adrenoceptor beta 2	Homo sapiens	33-41
31604529-8	2019	Altogether, N-termini of GRK2 and GRK3 efficiently simulate RKIP effects on beta-AR signaling in HEK293 cells and in cardiomyocytes by their binding to beta2-AR and, thus, provide important insights for the development of new strategies to modulate beta2-AR signaling.	Nitrogen	12-13	phosphatidylethanolamine binding protein 1	Homo sapiens	60-64
31604529-8	2019	Altogether, N-termini of GRK2 and GRK3 efficiently simulate RKIP effects on beta-AR signaling in HEK293 cells and in cardiomyocytes by their binding to beta2-AR and, thus, provide important insights for the development of new strategies to modulate beta2-AR signaling.	Nitrogen	12-13	adrenoceptor beta 2	Homo sapiens	76-83
31604529-8	2019	Altogether, N-termini of GRK2 and GRK3 efficiently simulate RKIP effects on beta-AR signaling in HEK293 cells and in cardiomyocytes by their binding to beta2-AR and, thus, provide important insights for the development of new strategies to modulate beta2-AR signaling.	Nitrogen	12-13	adrenoceptor beta 2	Homo sapiens	152-160
31604529-8	2019	Altogether, N-termini of GRK2 and GRK3 efficiently simulate RKIP effects on beta-AR signaling in HEK293 cells and in cardiomyocytes by their binding to beta2-AR and, thus, provide important insights for the development of new strategies to modulate beta2-AR signaling.	Nitrogen	12-13	adrenoceptor beta 2	Homo sapiens	249-257
31666677-5	2019	During nitrogen starvation conditions, Psp2 interacts with the 5" UTR of ATG1 and ATG13 transcripts in an RGG motif-dependent manner and with eIF4E and eIF4G2, components of the translation initiation machinery, to regulate the translation of these transcripts.	Nitrogen	7-15	regenerating family member 1 beta	Homo sapiens	39-43
30806950-4	2019	Traffic-related air pollutants or TRAP refers to a broad group of pollutants including elemental carbon, black soot, nitrogen dioxide (NO2), nitric oxide (NO), sulfur dioxide (SO2), particulate matter (PM2.5 and PM10), carbon monoxide (CO), and carbon dioxide (CO2).	Nitrogen	117-125	TRAP	Homo sapiens	34-38
31557614-2	2019	The known d-xylo stereoisomer of 1 (compound 2) along with two new analogues bearing nitrogen functions at the C-3" (3 and 4) has also been synthesized from the same sugar precursor.	Nitrogen	85-93	complement C3	Homo sapiens	111-124
31580948-1	2019	Human flavin-containing monooxygenase 3 (hFMO3) is a drug-metabolizing enzyme capable of performing N- or S-oxidation using the C4a-hydroperoxy intermediate.	Nitrogen	100-101	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	6-39
31580948-1	2019	Human flavin-containing monooxygenase 3 (hFMO3) is a drug-metabolizing enzyme capable of performing N- or S-oxidation using the C4a-hydroperoxy intermediate.	Nitrogen	100-101	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	41-46
31652301-6	2019	Here we have used different approaches to show that this event is accompanied by a specific change in the HDM2 structure that affects the HDM2 interactome, such as the N-termini HDM2 - p53 protein-protein interaction.	Nitrogen	168-169	MDM2 proto-oncogene	Homo sapiens	106-110
31652301-6	2019	Here we have used different approaches to show that this event is accompanied by a specific change in the HDM2 structure that affects the HDM2 interactome, such as the N-termini HDM2 - p53 protein-protein interaction.	Nitrogen	168-169	MDM2 proto-oncogene	Homo sapiens	138-142
31652301-6	2019	Here we have used different approaches to show that this event is accompanied by a specific change in the HDM2 structure that affects the HDM2 interactome, such as the N-termini HDM2 - p53 protein-protein interaction.	Nitrogen	168-169	MDM2 proto-oncogene	Homo sapiens	138-142
31575661-0	2019	ROS generation is stimulated by kappa opioid receptor activation through phosphorylated c-Jun-N-terminal kinase and inhibited by p38 MAPK activation.	Nitrogen	94-95	opioid receptor kappa 1	Homo sapiens	32-53
31695039-4	2019	The methyltransferase (MTase) domain of ZCCHC4 is packed against N-terminal GRF-type and C2H2 zinc finger domains and a C-terminal CCHC domain, creating an integrated RNA-binding surface.	Nitrogen	65-66	zinc finger CCHC-type containing 4	Homo sapiens	40-46
31538686-3	2019	For spin crossover in first-row transition metals coordinated by hydrogen, nitrogen, and carbon monoxide, we find the pressure required for spin transition to be a function of ligand position in the spectrochemical sequence.	Nitrogen	75-83	spindlin 1	Homo sapiens	140-144
31694180-3	2019	CCK-oligosaccharides induced the expression of phosphorylated-p38, extracellular-signal-regulated kinase (ERK), and c-Jun N-terminal kinase (JNK) and upregulation of phagocytic activity in RAW264.7 macrophages, suggesting their involvement in mitogen-activated protein kinase (MAPK) signaling pathway and phagocytosis.	Nitrogen	122-123	cholecystokinin	Mus musculus	0-3
31588916-4	2019	The results showed significant reduction in the body weight, heart rate (HR), hemoglobin contents, serum Ca2+ and reduction in the expression of mRNA of endothelial nitric oxide synthase (eNOS) and nuclear factor erythroid related factor 2 (nrf2) genes in aortic tissues with significant increase in arterial blood pressure (ABP), serum creatinine, blood urea nitrogen (BUN), plasma renin activity (PRA), K+ and phosphate (PO43-), urinary albumin excretion (UAE) and aortic VC in Adenine group compared to normal group (p < 0.05).	Nitrogen	360-368	nitric oxide synthase 3	Rattus norvegicus	153-186
31876282-4	2019	A considerable negative effect of histone H1 on EPC depending on its C- and N-tails was shown.	Nitrogen	76-77	H1.0 linker histone	Homo sapiens	34-44
31633363-2	2019	Various chiral hydrothiazole derivatives were readily provided in good yield with high enantioselectivity (up to 98% yield, 98.5:1.5 er) utilizing a chiral Mg(OTf)2/N,N"-dioxide complex as the catalyst under mild conditions.	Nitrogen	165-177	POU class 2 homeobox 2	Homo sapiens	159-164
31622939-3	2019	It was shown that GS2 mutants although smaller, slightly chlorotic and with the nitrogen metabolism impaired, were able to grow and complete their life cycle under ordinary air conditions.	Nitrogen	80-88	glutamine synthetase 2	Arabidopsis thaliana	18-21
31673848-0	2019	Simultaneous determination of paracetamol and p-aminophenol using glassy carbon electrode modified with nitrogen- and sulfur- co-doped carbon dots.	Nitrogen	104-112	poly(A) polymerase alpha	Homo sapiens	46-59
31673848-8	2019	Response to PAP is linear from 1.0 to 300 muM, and the detection limit is 38 nM (at S/N = 3).	Nitrogen	86-87	poly(A) polymerase alpha	Homo sapiens	12-15
31673848-10	2019	Graphical abstract Schematic representation of a novel electrochemical sensor based on N, S co-doped walnut shell carbon modified glassy carbon electrode for determination of paracetamol and p-aminophenol.	Nitrogen	87-88	poly(A) polymerase alpha	Homo sapiens	191-204
31695625-6	2019	Using coimmunoprecipitation, we confirmed the physical interaction between ITM2B or TMEM85 and N-terminal GLUT9 isoforms (GLUT9a and GLUT9b) in transfected HEK 293T cells and Xenopus oocytes, wherein ITM2B but not TMEM85 inhibited GLUT9-mediated urate uptake.	Nitrogen	95-96	ER membrane protein complex subunit 4	Homo sapiens	84-90
31695625-6	2019	Using coimmunoprecipitation, we confirmed the physical interaction between ITM2B or TMEM85 and N-terminal GLUT9 isoforms (GLUT9a and GLUT9b) in transfected HEK 293T cells and Xenopus oocytes, wherein ITM2B but not TMEM85 inhibited GLUT9-mediated urate uptake.	Nitrogen	95-96	ER membrane protein complex subunit 4 L homeolog	Xenopus laevis	214-220
31145609-10	2019	Further electron-nuclear double resonance studies with globally 15N-labeled mCP provided hyperfine couplings from the coordinating epsilon-nitrogen atoms of the His ligands (aiso = 4.3 MHz) as well as the distal delta-nitrogen atoms (aiso = 0.25 MHz).	Nitrogen	139-147	CD46 antigen, complement regulatory protein	Mus musculus	76-79
31626627-6	2019	Furthermore, nitrogen signals stimulated the expression of XTH9 to promote LRs.	Nitrogen	13-21	xyloglucan endotransglucosylase/hydrolase 9	Arabidopsis thaliana	59-63
31626627-7	2019	Genetic analysis revealed that the function of XTH9 was dependent on auxin-mediated ARF7/19 and downstream AFB3 in response to nitrogen signals.	Nitrogen	127-135	xyloglucan endotransglucosylase/hydrolase 9	Arabidopsis thaliana	47-51
31626627-8	2019	In addition, we identified another transcription factor, OBP4, that was also induced by nitrogen treatment, but the induction was much slower than that of XTH9.	Nitrogen	88-96	xyloglucan endotransglucosylase/hydrolase 9	Arabidopsis thaliana	155-159
31742034-14	2019	Correlation of matrix metalloproteinase-9 expression with cervical lymph node metastasis (N0, N1, N2, and N3) in patients with NPC showed a significant result (p &lt; 0.05).	Nitrogen	94-96	matrix metallopeptidase 9	Homo sapiens	15-41
31742034-14	2019	Correlation of matrix metalloproteinase-9 expression with cervical lymph node metastasis (N0, N1, N2, and N3) in patients with NPC showed a significant result (p &lt; 0.05).	Nitrogen	98-100	matrix metallopeptidase 9	Homo sapiens	15-41
31742034-14	2019	Correlation of matrix metalloproteinase-9 expression with cervical lymph node metastasis (N0, N1, N2, and N3) in patients with NPC showed a significant result (p &lt; 0.05).	Nitrogen	106-108	matrix metallopeptidase 9	Homo sapiens	15-41
31755042-9	2019	We found that the toxicity of (UGGAA)n is length- and expression level-dependent, and it was dampened by co-expressing TDP-43, FUS, and hnRNP A2/B1.	Nitrogen	36-38	TAR DNA-binding protein-43 homolog	Drosophila melanogaster	119-125
31755042-10	2019	Further investigation revealed that TDP-43 ameliorates (UGGAA)n toxicity by directly fixing the abnormal structure of (UGGAA)n.	Nitrogen	9-10	TAR DNA-binding protein-43 homolog	Drosophila melanogaster	36-42
31558698-5	2019	This synergism is dependent on the presence of the N-terminal, NuRD-binding motif in ZNF521, and is sensitive to HDAC (histone deacetylase) and GLI inhibitors.	Nitrogen	51-52	histone deacetylase 9	Homo sapiens	113-117
31558698-5	2019	This synergism is dependent on the presence of the N-terminal, NuRD-binding motif in ZNF521, and is sensitive to HDAC (histone deacetylase) and GLI inhibitors.	Nitrogen	51-52	histone deacetylase 9	Homo sapiens	119-138
31558698-5	2019	This synergism is dependent on the presence of the N-terminal, NuRD-binding motif in ZNF521, and is sensitive to HDAC (histone deacetylase) and GLI inhibitors.	Nitrogen	51-52	GLI family zinc finger 1	Homo sapiens	144-147
31620005-6	2019	C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P &lt; 0.01) at 175 mg kg-1 APAP dose, and phosphorylation levels of upstream proteins of JNK were also decreased markedly (P &lt; 0.05).	Nitrogen	6-7	mitogen-activated protein kinase 8	Mus musculus	44-47
31620005-6	2019	C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P &lt; 0.01) at 175 mg kg-1 APAP dose, and phosphorylation levels of upstream proteins of JNK were also decreased markedly (P &lt; 0.05).	Nitrogen	6-7	mitogen-activated protein kinase 8	Mus musculus	174-177
31608008-5	2019	In addition, we discovered that the expressions of cleaved Caspase-1, active N-terminal fragments of GSDMD (GSDMD-NT), IL-18, and the secretion of IL-1beta also increased in the kidneys of db/db mice.	Nitrogen	77-78	gasdermin D	Mus musculus	101-106
31184780-9	2019	The final step of path 1 is metathesis between Ni N3 bond of Int3 and Si H bond of PhSiH3 to afford N-silylated 1,2-dihydroproduct and regenerate 1 (DeltaG   = 4.5 kcal mol-1 ).	Nitrogen	47-48	notch receptor 4	Homo sapiens	61-65
31361945-0	2019	A Tyrosinase Inhibitor from a Nitrogen-Enriched Chemically Engineered Extract.	Nitrogen	30-38	tyrosinase	Homo sapiens	2-12
31361945-2	2019	The use of hydrazine monohydrate as a reagent to prepare chemically engineered extracts can lead to semisynthetic compounds that contain the portion N-N, a fragment rarely found in natural products and present in some tyrosinase inhibitors.	Nitrogen	149-152	tyrosinase	Homo sapiens	218-228
31555486-2	2019	B7x belongs to the Immunoglobulin superfamily and its protein structure is similar to other members with a N terminus peptide, IgV and IgC like extracellular domain with four cysteine residues.	Nitrogen	107-108	V-set domain containing T cell activation inhibitor 1	Homo sapiens	0-3
31327679-0	2019	Design, synthesis, biological evaluation of benzoyl amide derivatives containing nitrogen heterocyclic ring as potential VEGFR-2 inhibitors.	Nitrogen	81-89	kinase insert domain receptor	Homo sapiens	121-128
31302889-3	2019	The nitrogen removal efficiency gradually declined with the operating temperature decreasing, and the denitrification rate at 30  C was 5 times higher than that at 10  C. Meanwhile, it was found that a slight TOC accumulation only occurred at 30  C (with an average of 2.03 mg/L) and was avoided at 10~20  C. The reason for effluent TOC variation was further explained through the consumption and generation pathways of TOC in this system.	Nitrogen	4-12	rhomboid 5 homolog 2	Homo sapiens	209-212
31302889-3	2019	The nitrogen removal efficiency gradually declined with the operating temperature decreasing, and the denitrification rate at 30  C was 5 times higher than that at 10  C. Meanwhile, it was found that a slight TOC accumulation only occurred at 30  C (with an average of 2.03 mg/L) and was avoided at 10~20  C. The reason for effluent TOC variation was further explained through the consumption and generation pathways of TOC in this system.	Nitrogen	4-12	rhomboid 5 homolog 2	Homo sapiens	333-336
31302889-3	2019	The nitrogen removal efficiency gradually declined with the operating temperature decreasing, and the denitrification rate at 30  C was 5 times higher than that at 10  C. Meanwhile, it was found that a slight TOC accumulation only occurred at 30  C (with an average of 2.03 mg/L) and was avoided at 10~20  C. The reason for effluent TOC variation was further explained through the consumption and generation pathways of TOC in this system.	Nitrogen	4-12	rhomboid 5 homolog 2	Homo sapiens	333-336
31632477-5	2019	There was a significant association between increased expression of KLF6-SV1 with the pN and pTNM stages and poor survival in NSCLC patients.	Nitrogen	87-88	Kruppel like factor 6	Homo sapiens	68-76
31374171-4	2019	Herein, a "nitrogen-protected silica template" method is proposed to design a nanoantioxidant called an organosilica-based hollow mesoporous bilirubin nanoparticle (HMBRN), which can act as an excellent nanocarrier to codeliver GOx and TPZ.	Nitrogen	11-19	hydroxyacid oxidase 1	Homo sapiens	228-231
31393126-8	2019	Two N-glycosylation sites (N177 and N394), 3 sites (N145, N178, and N92), and 1 site of N183 were identified in MRJP1, MRJP2, and MRJP3, respectively.	Nitrogen	4-5	major royal jelly protein 1	Apis mellifera	112-117
31390828-1	2019	Protein arginine methyltransferase 1 (PRMT1) can catalyze protein arginine methylation by transferring the methyl group from S-adenosyl-L-methionine (SAM) to the guanidyl nitrogen atom of protein arginine, which influences a variety of biological processes.	Nitrogen	171-179	protein arginine methyltransferase 1	Homo sapiens	0-36
31390828-1	2019	Protein arginine methyltransferase 1 (PRMT1) can catalyze protein arginine methylation by transferring the methyl group from S-adenosyl-L-methionine (SAM) to the guanidyl nitrogen atom of protein arginine, which influences a variety of biological processes.	Nitrogen	171-179	protein arginine methyltransferase 1	Homo sapiens	38-43
30891880-8	2019	Some (CAG)n -containing genes including TBP, ATN1 and HTT modified AAO with variance ranging from 0.8% to 3.8% and tended to decrease or delay AAO.	Nitrogen	10-11	TATA-box binding protein	Homo sapiens	40-43
31213504-6	2019	In nitrogen replete environments, TorC1 is activated, thereby inhibiting the PTap42-Sit4 and PTap42-PP2A (Pph21/Pph22-Tpd3, Pph21,22-Rts1/Cdc55) phosphatase complexes.	Nitrogen	3-11	phosphoprotein phosphatase 2A catalytic subunit PPH22	Saccharomyces cerevisiae S288C	112-117
31356638-0	2019	Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation.	Nitrogen	26-27	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	46-49
31283210-2	2019	With Cu(OTf)2 as the catalyst, the reaction of alkenes, (bpy)Zn(CF3)2, and N-fluorobis(benzenesulfonyl)imide (NFSI) at room temperature provides the corresponding aminotrifluoromethylation products in satisfactory yields with high regioselectivity opposite to those driven by CF3 radical addition.	Nitrogen	75-76	POU class 2 homeobox 2	Homo sapiens	5-13
31344930-9	2019	The finding of this study provides a systematic understanding that Pep4p may serve as a regulating factor for cell physiology and metabolic processes in S. cerevisiae under a nitrogen stress environment.	Nitrogen	175-183	proteinase A	Saccharomyces cerevisiae S288C	67-72
31199615-2	2019	Single negatively charged nitrogen-vacancy (NV-) centers in diamond offer high sensitivity and spatial resolution in the optical detection of weak magnetic fields produced by a spin bath but often require long acquisition times on the order of seconds.	Nitrogen	26-34	spindlin 1	Homo sapiens	177-181
31354711-10	2019	Increased TLR7 protein expression in renal macrophages and cDCs correlated with disease parameters such as blood urea nitrogen (BUN) levels and the frequency of leukocytes infiltrating the kidney.	Nitrogen	118-126	toll-like receptor 7	Mus musculus	10-14
30707264-5	2019	The ionization process was affected by the temperature of the two nitrogen streams used to vaporize the solvent and the analytes, particularly for RDX and HMX, which are thermolabile compounds.	Nitrogen	66-74	radixin	Homo sapiens	147-150
30919496-5	2019	Values of Km , alpha, n, and Ks for the immobilized enzyme were calculated to be 1.25 x 10-2  microM, 0.56, 3.19, and 0.28 Sec-1 , respectively.	Nitrogen	22-23	secretory blood group 1, pseudogene	Homo sapiens	123-128
31115488-1	2019	Congenital disorder of glycosylation (CDG) type Ia is a multisystem disorder that occurs due to mutations in the phosphomannomutase 2 (PMM2) gene, which encodes for an enzyme involved in the N-glycosylation pathway.	Nitrogen	191-192	phosphomannomutase 2	Homo sapiens	113-133
31115488-1	2019	Congenital disorder of glycosylation (CDG) type Ia is a multisystem disorder that occurs due to mutations in the phosphomannomutase 2 (PMM2) gene, which encodes for an enzyme involved in the N-glycosylation pathway.	Nitrogen	191-192	phosphomannomutase 2	Homo sapiens	135-139
31051313-7	2019	The molecular docking and activity experiments indicated that the N-methyl substitution on the side chain of these drugs played a significant role in activating MRGPRX2, while the phenothiazine tricyclic ring was associated with the inhibiting effect on the H1R.	Nitrogen	66-67	MAS-related GPR, member X2	Mus musculus	161-168
30925039-7	2019	N-Dealkylation yielding TBF-A directly was catalyzed by CYP2C19 and 3A4 similarly.	Nitrogen	0-1	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	56-63
31181624-3	2019	The aim of this pilot study was to determine, in PLWH, the relationship between atherosclerosis assessed by carotid intima-media thickness (CIMT) and (A) plasma antioxidant micronutrients and oxidative stress or (B) red blood cell polyunsaturated fatty acids (RBC PUFA), particularly long chain omega-3 polyunsaturated fatty acids (n-3 PUFA).	Nitrogen	42-43	pumilio RNA binding family member 3	Homo sapiens	264-268
31181624-3	2019	The aim of this pilot study was to determine, in PLWH, the relationship between atherosclerosis assessed by carotid intima-media thickness (CIMT) and (A) plasma antioxidant micronutrients and oxidative stress or (B) red blood cell polyunsaturated fatty acids (RBC PUFA), particularly long chain omega-3 polyunsaturated fatty acids (n-3 PUFA).	Nitrogen	42-43	pumilio RNA binding family member 3	Homo sapiens	336-340
31239707-1	2019	Background: Being an important N-glycosylation enzyme in eukaryotic cells, Golgi alpha-mannosidaseII (GMII) has been suggested to function as a target for cancer treatment based on the inhibitory effect on cancer growth and metastasis by the swainsonine, an inhibitor of GMII.	Nitrogen	31-32	mannosidase alpha class 2A member 1	Homo sapiens	75-100
31239707-1	2019	Background: Being an important N-glycosylation enzyme in eukaryotic cells, Golgi alpha-mannosidaseII (GMII) has been suggested to function as a target for cancer treatment based on the inhibitory effect on cancer growth and metastasis by the swainsonine, an inhibitor of GMII.	Nitrogen	31-32	mannosidase alpha class 2A member 1	Homo sapiens	102-106
31049577-7	2019	Large differences between current and target intakes existed for whole grains, sodium, long-chain n-3 polyunsaturated fats, polyunsaturated fats, and fruits.	Nitrogen	13-14	chromosome 10 open reading frame 90	Homo sapiens	118-122
31049577-7	2019	Large differences between current and target intakes existed for whole grains, sodium, long-chain n-3 polyunsaturated fats, polyunsaturated fats, and fruits.	Nitrogen	13-14	chromosome 10 open reading frame 90	Homo sapiens	140-144
31058508-3	2019	The reaction was found to go through an in situ generated copper- N-heterocyclic carbene, which was then oxidized into cyclic urea derivatives possessing alkyl, benzyl, aryl, hydroxy, Boc-protected, and tertiary amine groups.	Nitrogen	66-67	BOC cell adhesion associated, oncogene regulated	Homo sapiens	184-187
30825868-5	2019	This is mainly attributed to the Hg2+ (or Ag+) forms a stable five-membered ring with the N atom in Schiff base CN and the S atom in thiourea.	Nitrogen	90-91	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	33-36
30873657-3	2019	Impairment in N-glycosylation of CaV2.1 promotes gain-of-function effects and may participate in cerebellar syndrome in PMM2-CDG.	Nitrogen	14-15	calcium voltage-gated channel subunit alpha1 A	Homo sapiens	33-39
30873657-3	2019	Impairment in N-glycosylation of CaV2.1 promotes gain-of-function effects and may participate in cerebellar syndrome in PMM2-CDG.	Nitrogen	14-15	phosphomannomutase 2	Homo sapiens	120-124
30636324-7	2019	We also demonstrate that AHK4, the Arabidopsis orthologue of LHK1, is able to regulate M. loti infection in L. japonicus, suggesting that an endogenous cytokinin receptor could be sufficient for engineering nitrogen-fixing root nodule symbiosis in nonlegumes.	Nitrogen	207-215	Spontaneous nodule formation 2	Lotus japonicus	61-65
30900877-4	2019	Specifically, by utilizing active plasma that is generated with an asymmetric electrical field during the electrochemical reaction at the surface of the submerged cathode tip, we are able to achieve doping of nitrogen atoms, from the electrolytes, into the semiconducting 2H-MX2 structures during their exfoliation process from the bulk states, forming N-doped MX2.	Nitrogen	209-217	MX dynamin like GTPase 2	Homo sapiens	275-278
30900877-4	2019	Specifically, by utilizing active plasma that is generated with an asymmetric electrical field during the electrochemical reaction at the surface of the submerged cathode tip, we are able to achieve doping of nitrogen atoms, from the electrolytes, into the semiconducting 2H-MX2 structures during their exfoliation process from the bulk states, forming N-doped MX2.	Nitrogen	209-217	MX dynamin like GTPase 2	Homo sapiens	361-364
31041303-4	2019	For example, Fe/N-doped graphitic SACs have exhibited spin-state dependent reactivity that remains poorly understood.	Nitrogen	16-17	spindlin 1	Homo sapiens	54-58
30884227-2	2019	Here, we theoretically study the spin dynamics of interacting nitrogen-vacancy (NV) and substitutional nitrogen (P1) centers in diamond to show that outside protons spin-polarize efficiently upon a magnetic field sweep across the NV-P1 level anticrossing.	Nitrogen	62-70	spindlin 1	Homo sapiens	33-37
30884227-2	2019	Here, we theoretically study the spin dynamics of interacting nitrogen-vacancy (NV) and substitutional nitrogen (P1) centers in diamond to show that outside protons spin-polarize efficiently upon a magnetic field sweep across the NV-P1 level anticrossing.	Nitrogen	62-70	spindlin 1	Homo sapiens	165-169
30884227-2	2019	Here, we theoretically study the spin dynamics of interacting nitrogen-vacancy (NV) and substitutional nitrogen (P1) centers in diamond to show that outside protons spin-polarize efficiently upon a magnetic field sweep across the NV-P1 level anticrossing.	Nitrogen	103-111	spindlin 1	Homo sapiens	33-37
30884227-2	2019	Here, we theoretically study the spin dynamics of interacting nitrogen-vacancy (NV) and substitutional nitrogen (P1) centers in diamond to show that outside protons spin-polarize efficiently upon a magnetic field sweep across the NV-P1 level anticrossing.	Nitrogen	103-111	spindlin 1	Homo sapiens	165-169
30835121-2	2019	This strategy provides the synthesis of valuable SCF3-substituted quinoline and isoquinoline systems via the construction of one C(sp2)-SCF3 bond and one C-N bond within one process.	Nitrogen	156-157	KIT ligand	Homo sapiens	49-52
30773397-4	2019	Furthermore, individual SH2 domains of SHP-2 strongly engage with the unphosphorylated N-ITIM of 3DL1-cyto, while binding of the tandem SHP-2 SH2 domains to the bis-phosphorylated ITIMs results in more extensive conformational changes in segments I and III.	Nitrogen	87-88	protein tyrosine phosphatase non-receptor type 11	Homo sapiens	39-44
30658808-3	2019	The nitrogen adsorption property of ZIF-8@CNF@cellulose foam was 30 times higher than pure cellulose foam.	Nitrogen	4-12	NPHS1 adhesion molecule, nephrin	Homo sapiens	42-45
30848371-7	2019	Graphical abstract Schematic presentation of the water-soluble nitrogen-doped carbon dots (C-dots) as a fluorescent probe for Cr6+ based on an inner filter effect.	Nitrogen	63-71	teratocarcinoma-derived growth factor 1 pseudogene 6	Homo sapiens	126-129
30338870-3	2019	GRAIL was derived using objective variables (creatinine, blood urea nitrogen, age, gender, race, and albumin) to estimate GFR based on timing of measurement relative to LT and degree of renal dysfunction (www.bswh.md/grail).	Nitrogen	68-76	ring finger protein 128	Homo sapiens	0-5
31245758-5	2019	DGL1 encodes a subunit of the oligosaccharyltransferse (OST) complex which catalyzes the formation of N-glycosidic bonds in N-glycosylation.	Nitrogen	102-103	dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein	Arabidopsis thaliana	0-4
31245758-8	2019	The S-nitrosylation and N-glycosylation profiles were also modified in dgl1-3 and gsnor1-3.	Nitrogen	24-25	dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit family protein	Arabidopsis thaliana	71-75
30760632-0	2019	Human G protein-coupled receptor 30 is N-glycosylated and N-terminal domain asparagine 44 is required for receptor structure and activity.	Nitrogen	39-40	G protein-coupled estrogen receptor 1	Homo sapiens	6-35
30760632-4	2019	Here, we used human embryonic kidney (HEK) 293 (HEK293) cells ectopically expressing N-terminally FLAG-tagged human GPR30 and three unique antibodies (Ab) specifically targetting the receptor N-terminal domain (N-domain) to investigate the role of N-glycosylation in receptor maturation and activity, the latter assayed by constitutive receptor-stimulated extracellular-regulated protein kinase (ERK) 1/2 (ERK1/2) activity.	Nitrogen	85-86	G protein-coupled estrogen receptor 1	Homo sapiens	116-121
30721035-3	2019	Various peculiar nitrogen polymerization forms composed of single/double nitrogen-nitrogen bonds were found at the nitrogen-rich condition, such as N -chains in P21/ m-SeN3, oligomeric N8-chains in P1-SeN4, and distorted N63- anion rings in P1-SeN5.	Nitrogen	17-25	senescence (cellular)-related 3	Homo sapiens	168-172
30906589-1	2019	Flavin containing monooxygenase 3 [FMO3] encodes dimethylaniline monooxygenase [N-oxide-forming] 3, which breaks down nitrogen-containing compounds, and has been implicated in blood pressure regulation.	Nitrogen	118-126	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	0-33
30906589-1	2019	Flavin containing monooxygenase 3 [FMO3] encodes dimethylaniline monooxygenase [N-oxide-forming] 3, which breaks down nitrogen-containing compounds, and has been implicated in blood pressure regulation.	Nitrogen	118-126	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	35-39
30906589-1	2019	Flavin containing monooxygenase 3 [FMO3] encodes dimethylaniline monooxygenase [N-oxide-forming] 3, which breaks down nitrogen-containing compounds, and has been implicated in blood pressure regulation.	Nitrogen	118-126	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	49-98
30566828-0	2019	N-Linked Glycosylation-Dependent and -Independent Mechanisms Regulating CTRP12 Cleavage, Secretion, and Stability.	Nitrogen	0-1	C1q and TNF related 12	Homo sapiens	72-78
30566828-6	2019	When N-linked glycosylation was inhibited by tunicamycin or abolished by the N39Q, N39A, or T41A mutation, CTRP12 cleavage was enhanced.	Nitrogen	5-6	C1q and TNF related 12	Homo sapiens	107-113
30575143-3	2019	Here, a radical concept of building active metal-nitrogen moieties with unsaturated nitrogen coordination on a porous surface by directly growing metallic porous metal nitride (Fe3 N and Ta5 N6 ) single crystals at unprecedented 2 cm scale is reported.	Nitrogen	49-57	trace amine associated receptor 8	Homo sapiens	187-190
30575143-5	2019	The unsaturated metal-nitrogen moieties (Fe6 -N and Ta5 -N3 ) with unique electronic structures demonstrate enhanced electrocatalysis performance and durability.	Nitrogen	22-30	trace amine associated receptor 8	Homo sapiens	52-55
30420260-1	2019	Polymorphic human flavin-containing monooxygenase (FMO) 3 is an important drug-metabolizing enzyme for nitrogen- or sulfur-containing compounds.	Nitrogen	103-111	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	18-57
30420260-8	2019	Further analysis indicated that two of these variants, FMO3 G530A and R417H, showed significantly lower benzydamine N-oxygenation in liver microsomes of the homozygotes as compared with wild-type animals.	Nitrogen	116-117	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	55-59
30528026-9	2019	In April, both aspects limited PDR; while only nitrogen sources limited PDR in August, due to depleted nitrate and enhanced denitrifying bacteria activity.	Nitrogen	47-55	PDR	Homo sapiens	72-75
30058762-4	2019	Indeed, on each of the 6 N-glycosylation sites of the IDUA, a single N-glycan composed of a core Man3 GlcNAc2 carrying one beta(1,2)-xylose and one alpha(1,3)-fucose epitope (M3XFGN2) was identified, highlighting the high homogeneity of the production system.	Nitrogen	25-26	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	123-131
30308895-8	2019	Further functional simulation of these bacterial herds unveiled the change of Ca2+ and available phosphorus might disturb the soil carbon and nitrogen metabolism, and thus weakened soil quality.	Nitrogen	142-150	carbonic anhydrase 2	Homo sapiens	78-81
30308929-0	2019	The impact of ship emissions on PM2.5 and the deposition of nitrogen and sulfur in Yangtze River Delta, China.	Nitrogen	60-68	inositol polyphosphate-5-phosphatase D	Homo sapiens	14-18
30308929-11	2019	Further investigation revealed that ship emissions have caused an evident increase of dry nitrogen deposition in NO2 and HNO3, while a slight decrease in NH3 over YRD region.	Nitrogen	90-98	inositol polyphosphate-5-phosphatase D	Homo sapiens	36-40
30308929-12	2019	These results indicated that comprehensive regulations of ship emissions are required considering their adverse effects on the ambient concentration of PM2.5 and the deposition of sulfur and nitrogen.	Nitrogen	191-199	inositol polyphosphate-5-phosphatase D	Homo sapiens	58-62
30933439-11	2019	Mechanistically, TRPM2 downregulation causes an increase in the intracellular levels of reactive oxygen (ROS) and nitrogen (RNS) species, which in turn causes DNA damage and JNK activation leading to G2/M arrest, and an ultimate cell death.	Nitrogen	114-122	transient receptor potential cation channel, subfamily M, member 2	Mus musculus	17-22
30933439-11	2019	Mechanistically, TRPM2 downregulation causes an increase in the intracellular levels of reactive oxygen (ROS) and nitrogen (RNS) species, which in turn causes DNA damage and JNK activation leading to G2/M arrest, and an ultimate cell death.	Nitrogen	114-122	mitogen-activated protein kinase 8	Mus musculus	174-177
30843179-5	2019	TSHR is abundantly N-glycosylated, due to the presence of six N-glycosylation sites in the extracellular domain (Asn77, Asn99, Asn113, Asn177, Asn198, Asn302), mostly evolutionarily conserved.	Nitrogen	19-20	thyroid stimulating hormone receptor	Homo sapiens	0-4
30473282-4	2019	The important influence of secondary reactions on PNC2.5 was inferred due to higher correlation coefficients between PNC2.5 and SO42-, NO3-, NH4+ (r=0.78-0.89; p&lt;0.01) and between PNC2.5 and ratios that represent the conversion of nitrogen and sulfur oxides to particulate matter (r=0.42-0.49; p&lt;0.01).	Nitrogen	234-242	solute carrier family 25 member 36	Homo sapiens	50-54
30473282-4	2019	The important influence of secondary reactions on PNC2.5 was inferred due to higher correlation coefficients between PNC2.5 and SO42-, NO3-, NH4+ (r=0.78-0.89; p&lt;0.01) and between PNC2.5 and ratios that represent the conversion of nitrogen and sulfur oxides to particulate matter (r=0.42-0.49; p&lt;0.01).	Nitrogen	234-242	solute carrier family 25 member 36	Homo sapiens	117-121
30473282-4	2019	The important influence of secondary reactions on PNC2.5 was inferred due to higher correlation coefficients between PNC2.5 and SO42-, NO3-, NH4+ (r=0.78-0.89; p&lt;0.01) and between PNC2.5 and ratios that represent the conversion of nitrogen and sulfur oxides to particulate matter (r=0.42-0.49; p&lt;0.01).	Nitrogen	234-242	solute carrier family 25 member 36	Homo sapiens	117-121
31580197-5	2019	Importantly, we also found that the relative ratio of carbon to nitrogen (C/N) was greatly enhanced by BIG deficiency.	Nitrogen	64-72	auxin transport protein (BIG)	Arabidopsis thaliana	103-106
30558367-4	2018	By inserting TiO2 between Ti and n-Si, Ids of bendable single crystal SiNMs TFTs increases 3-10 times than those without the TiO2 insertion layer.	Nitrogen	4-5	iduronate 2-sulfatase	Homo sapiens	39-42
30509163-6	2018	Under N limitations, we detected accumulated anthocyanin, reduced nitrate (NO3-) and total N concentrations, and enhanced glutamine synthetase activity in the N-starved rapeseed plants.	Nitrogen	6-7	glutamine synthetase, chloroplastic	Brassica napus	122-142
30166153-8	2018	The production of ethyl esters was slightly higher after the addition of any type of nitrogen; the production of higher alcohols other than propanol was unchanged, and acetate esters were overproduced due to the overexpression of the genes ATF1 and ATF2.	Nitrogen	85-93	alcohol O-acetyltransferase	Saccharomyces cerevisiae S288C	240-244
31458237-6	2018	Both network PIMs displayed high theoretical ideal adsorbed solution theory CO2/N2 selectivities (51 and 94 at 273 K vs 34 and 84 at 298 K for MP1 and MP2, respectively).	Nitrogen	80-82	pitrilysin metallopeptidase 1	Homo sapiens	143-146
31458237-7	2018	The high selectivities of MP1 and MP2 were confirmed by experimental column breakthrough experiments with CO2/N2 selectivity values of 23 and 45, respectively.	Nitrogen	110-112	pitrilysin metallopeptidase 1	Homo sapiens	26-29
31458237-8	2018	Besides the promising CO2 capture and CO2/N2 selectivity properties, MP1 also demonstrated high sorption capacity for toxic volatile organic vapors.	Nitrogen	42-44	pitrilysin metallopeptidase 1	Homo sapiens	69-72
30517807-1	2018	We experimentally observe Floquet Raman transitions in the weakly driven solid-state spin system of a nitrogen-vacancy center in diamond.	Nitrogen	102-110	spindlin 1	Homo sapiens	85-89
29982029-7	2018	The Bi2S3@N-G/GC electrode demonstrated a wide concentration range for H2O2, from 10 to 42,960 muM, with a sensitivity of 0.1535 muA muM-1 and an obtained limit of detection of 1.9 muM.	Nitrogen	10-11	PWWP domain containing 3A, DNA repair factor	Homo sapiens	133-138
30374089-3	2018	Here, we show that nla and pho2 (also known as ubc24) plants develop rapid leaf senescence under nitrogen-starvation condition, whereas ore1 and nla/ore1 and pho2 (ubc24)/ore1 plants stay green.	Nitrogen	97-105	phosphate 2	Arabidopsis thaliana	27-31
30374089-3	2018	Here, we show that nla and pho2 (also known as ubc24) plants develop rapid leaf senescence under nitrogen-starvation condition, whereas ore1 and nla/ore1 and pho2 (ubc24)/ore1 plants stay green.	Nitrogen	97-105	phosphate 2	Arabidopsis thaliana	47-52
30192960-5	2018	Introduction of SlCPT5 into the polyprenol-deficient yeast Deltarer2 mutant resulted in the accumulation of Pren-11 in yeast cells, restored proper protein N-glycosylation and rescued the temperature-sensitive growth phenotype that is associated with its polyprenol deficiency.	Nitrogen	156-157	dehydrodolichyl diphosphate synthase 2	Solanum lycopersicum	16-22
29958959-13	2018	In vivo, LEP treatment significantly reduced the effects of CCl4 intoxication on serum liver biomarkers (AST, ALT, LDH, and GGT) and the effect of cisplatin on serum renal biomarkers (urea, blood urea nitrogen, creatinine, and uric acid).	Nitrogen	201-209	chemokine (C-C motif) ligand 4	Mus musculus	60-64
30212215-0	2018	Probing a Spin Transfer Controlled Magnetic Nanowire with a Single Nitrogen-Vacancy Spin in Bulk Diamond.	Nitrogen	67-75	spindlin 1	Homo sapiens	10-14
30212215-0	2018	Probing a Spin Transfer Controlled Magnetic Nanowire with a Single Nitrogen-Vacancy Spin in Bulk Diamond.	Nitrogen	67-75	spindlin 1	Homo sapiens	84-88
30333840-0	2018	Corrigendum: Alleviation of Nitrogen and Sulfur Deficiency and Enhancement of Photosynthesis in Arabidopsis thaliana by Overexpression of Uroporphyrinogen III Methyltransferase (UPM1).	Nitrogen	28-36	urophorphyrin methylase 1	Arabidopsis thaliana	178-182
30183042-2	2018	X-ray crystallography of the [MnII(L7BQ)(OTf)2] complex shows a monomeric MnII center with the L7BQ ligand providing four donor nitrogen atoms in the equatorial field, with two triflate ions bound in the axial positions.	Nitrogen	128-136	POU class 2 homeobox 2	Homo sapiens	41-46
30054192-1	2018	With the purpose of identifying novel selective kappa opioid receptor (KOR) antagonists as potential antidepressants from nepenthone analogues, starting from N-nor-N-cyclopropylmethyl-nepenthone (SLL-020ACP), a highly selective and potent KOR agonist, a series of 7beta-methyl-nepenthone analogues was conceived, synthesized and assayed on opioid receptors based on the concept of hybridization.	Nitrogen	158-159	opioid receptor kappa 1	Homo sapiens	71-74
32734050-5	2018	The richest sources of dietary n-3 LC-PUFA are derived from marine products, while forage and oilseeds such as flaxseed, canola, and their oils are abundant in ALA.	Nitrogen	31-32	pumilio RNA binding family member 3	Homo sapiens	38-42
29759420-8	2018	LOXL2 inhibitor treatment also reduced glomerulosclerosis, expression of MMP-10, MMP-12, and MCP-1 mRNA in glomeruli, and decreased albuminuria and blood urea nitrogen.	Nitrogen	159-167	lysyl oxidase-like 2	Mus musculus	0-5
30061496-1	2018	Type I disorders of glycosylation (CDG), the most frequent of which is phosphomannomutase 2 (PMM2-CDG), are a group of diseases causing the incomplete N-glycosylation of proteins.	Nitrogen	151-152	phosphomannomutase 2	Homo sapiens	71-91
30061496-1	2018	Type I disorders of glycosylation (CDG), the most frequent of which is phosphomannomutase 2 (PMM2-CDG), are a group of diseases causing the incomplete N-glycosylation of proteins.	Nitrogen	151-152	phosphomannomutase 2	Homo sapiens	93-97
30105014-1	2018	SP-D can inhibit hemagglutination and infectivity of IAV, in addition to reducing neuraminidase (NA) activity via its carbohydrate recognition domain (CRD) binding to carbohydrate patterns (N-linked mannosylated) on NA and hemagglutinin (HA) of IAV.	Nitrogen	97-98	surfactant protein D	Homo sapiens	0-4
30116500-9	2018	Treatment with PRP attenuated the severity of CP-induced nephrotoxicity as evidenced by suppressed creatinine, blood urea nitrogen (BUN), and N-acetyl glucosaminidase (NAG) levels.	Nitrogen	122-130	proline rich protein 2-like 1	Rattus norvegicus	15-18
30065132-4	2018	Although T-N was effectively removed in the two different operating conditions, increase in the fraction of recirculation time results in tiny deterioration of nitrogen removal efficiency in the B-MBR.	Nitrogen	160-168	translocator protein	Homo sapiens	197-200
29796455-5	2018	Simulated STM images suggested the change in electron density that would occur upon adsorption of hydroxylamine in various adsorption configurations, and specifically indicated the N-O dissociative product to have greater electron density around the amine groups, and the hydroxyl groups to mainly contribute electron density to the unoccupied electronic states.	Nitrogen	181-182	sulfotransferase family 1A member 3	Homo sapiens	10-13
29547901-6	2018	Regarding the latter, we show that the 55 kDa N-glycosylated hNOT-1/ALG3-1 molecule binds the N-glycosylated CREB3 precursor but does not interact with CREB3"s proteolytic products specific to the endoplasmic reticulum and to the nucleus.	Nitrogen	46-47	CCR4-NOT transcription complex subunit 1	Homo sapiens	61-67
28446076-7	2018	In contrast, HI 6 and 2-PAM showed high binding energy values with great contribution of the amino acid Asp74, demonstrating the importance of the quaternary nitrogen to the affinity and interaction of the oximes/AChE tabun-inhibited complexes.	Nitrogen	158-166	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	24-27
29431199-0	2018	N-glycosylation by N-acetylglucosaminyltransferase V enhances the interaction of CD147/basigin with integrin beta1 and promotes HCC metastasis.	Nitrogen	0-1	integrin subunit beta 1	Homo sapiens	100-114
29755357-0	2018	N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting.	Nitrogen	0-1	lipocalin 2	Homo sapiens	19-30
29755357-8	2018	In sum, our data indicate that the N-glycosylation of LCN2 is not required for proper secretion and exosome cargo recruitment in different cell types, but might be relevant to increase overall solubility.	Nitrogen	35-36	lipocalin 2	Homo sapiens	54-58
29350621-2	2018	The CNF was obtained by annealing electrospun poly-acrylonitrile (PAN) in nitrogen (N2).	Nitrogen	74-82	NPHS1 adhesion molecule, nephrin	Homo sapiens	4-7
29350621-2	2018	The CNF was obtained by annealing electrospun poly-acrylonitrile (PAN) in nitrogen (N2).	Nitrogen	84-86	NPHS1 adhesion molecule, nephrin	Homo sapiens	4-7
29545574-6	2018	Fusion of the extracellular domain (M domain) of protein tyrosine phosphatase receptor type C (CD45), which contains four putative N-glycosylation sites to a model protein, leptin at the C-terminus, increased recombinant protein levels by 6.1 fold.	Nitrogen	131-132	protein tyrosine phosphatase receptor type C	Homo sapiens	95-99
29540771-5	2018	According to the models, the optimal process parameters which maximize cold-water-insoluble nitrogen and minimize hot-water-insoluble nitrogen for the synthesis of urea formaldehyde were as follows urea: formaldehyde molar ratio was 1.33, reaction temperature was 43.5  C, and reaction time was 1.64 h. Under these conditions, the content of cold-water-insoluble nitrogen was 22.14%, and hot-water-insoluble nitrogen was 9.87%.	Nitrogen	134-142	alcohol dehydrogenase iron containing 1	Homo sapiens	114-117
29540771-5	2018	According to the models, the optimal process parameters which maximize cold-water-insoluble nitrogen and minimize hot-water-insoluble nitrogen for the synthesis of urea formaldehyde were as follows urea: formaldehyde molar ratio was 1.33, reaction temperature was 43.5  C, and reaction time was 1.64 h. Under these conditions, the content of cold-water-insoluble nitrogen was 22.14%, and hot-water-insoluble nitrogen was 9.87%.	Nitrogen	134-142	alcohol dehydrogenase iron containing 1	Homo sapiens	114-117
29540771-5	2018	According to the models, the optimal process parameters which maximize cold-water-insoluble nitrogen and minimize hot-water-insoluble nitrogen for the synthesis of urea formaldehyde were as follows urea: formaldehyde molar ratio was 1.33, reaction temperature was 43.5  C, and reaction time was 1.64 h. Under these conditions, the content of cold-water-insoluble nitrogen was 22.14%, and hot-water-insoluble nitrogen was 9.87%.	Nitrogen	134-142	alcohol dehydrogenase iron containing 1	Homo sapiens	114-117
29330305-5	2018	Tethering recombinant CD16a to the membrane by including the transmembrane and intracellular domains and via coexpression with the Fc epsilon receptor gamma-chain in HEK293F cells was expected to produce N-glycoforms similar to NK cell-derived CD16a but yielded N-glycoforms different from NK cell-derived CD16a and recombinant soluble CD16a.	Nitrogen	204-205	Fc gamma receptor IIIa	Homo sapiens	22-27
29330305-5	2018	Tethering recombinant CD16a to the membrane by including the transmembrane and intracellular domains and via coexpression with the Fc epsilon receptor gamma-chain in HEK293F cells was expected to produce N-glycoforms similar to NK cell-derived CD16a but yielded N-glycoforms different from NK cell-derived CD16a and recombinant soluble CD16a.	Nitrogen	204-205	Fc gamma receptor IIIa	Homo sapiens	244-249
29330305-5	2018	Tethering recombinant CD16a to the membrane by including the transmembrane and intracellular domains and via coexpression with the Fc epsilon receptor gamma-chain in HEK293F cells was expected to produce N-glycoforms similar to NK cell-derived CD16a but yielded N-glycoforms different from NK cell-derived CD16a and recombinant soluble CD16a.	Nitrogen	204-205	Fc gamma receptor IIIa	Homo sapiens	244-249
29330305-5	2018	Tethering recombinant CD16a to the membrane by including the transmembrane and intracellular domains and via coexpression with the Fc epsilon receptor gamma-chain in HEK293F cells was expected to produce N-glycoforms similar to NK cell-derived CD16a but yielded N-glycoforms different from NK cell-derived CD16a and recombinant soluble CD16a.	Nitrogen	204-205	Fc gamma receptor IIIa	Homo sapiens	244-249
29518046-8	2018	Co-expression-network analysis of TFs with closely related profiles to known Nitrate-responsive genes identified GLK5, GLK8 and NLP15 as candidate regulators of genes repressed under low Nitrogen conditions, while bZIP108 might play a role in gene activation.	Nitrogen	187-195	Transcription factor NIGT1	Zea mays	113-117
29564399-7	2018	There is one ortholog of GZF3 and DAL80, which represses expression of genes in preferred nitrogen sources.	Nitrogen	90-98	Dal80p	Saccharomyces cerevisiae S288C	34-39
29483571-7	2018	Co-crystal structure analysis revealed the presence of the N-methylated product of JBSNF-000088 bound to the NNMT protein.	Nitrogen	59-60	nicotinamide N-methyltransferase	Mus musculus	109-113
29436478-5	2018	Two major upstream signaling pathways, the Ssy1-Ptr3-Ssy5 sensor system and the target of rapamycin pathway, which are responsible for sensing extracellular and intracellular nitrogen, respectively, are discussed.	Nitrogen	175-183	Ssy1p	Saccharomyces cerevisiae S288C	43-47
29436478-5	2018	Two major upstream signaling pathways, the Ssy1-Ptr3-Ssy5 sensor system and the target of rapamycin pathway, which are responsible for sensing extracellular and intracellular nitrogen, respectively, are discussed.	Nitrogen	175-183	Ssy5p	Saccharomyces cerevisiae S288C	53-57
29266417-2	2018	For the first time, a Cu-based MOF, i.e., Cu-NPMOF is used, whose linkers contain nitrogen and phosphorus heteroatoms, as a single precursor and template to prepare novel Cu3 P nanoparticles (NPs) coated by a N,P-codoped carbon shell that is extended to a hierarchical porous carbon matrix with identical uniform N and P doping (termed Cu3 P@NPPC) as an electrocatalyst.	Nitrogen	45-46	natriuretic peptide C	Homo sapiens	336-346
29197127-3	2018	However, the metabolic utilisation of preferred carbon and nitrogen sources, encountered in a host niche-dependent manner, is known as carbon catabolite and nitrogen catabolite repression (CCR, NCR), and has been shown to be important for virulence.	Nitrogen	59-67	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	194-197
29105162-7	2018	The reaction of [(PNN)Fe(CO)2 ] with HBpin (4,4,5,5-tetramethyl-1,3,2-dioxaborolane) resulted in the reduction of the metal center (by release of H2 ) and borylation of the pyrazole beta-nitrogen atom.	Nitrogen	187-195	pinin, desmosome associated protein	Homo sapiens	18-21
29472934-0	2017	Alleviation of Nitrogen and Sulfur Deficiency and Enhancement of Photosynthesis in Arabidopsis thaliana by Overexpression of Uroporphyrinogen III Methyltransferase (UPM1).	Nitrogen	15-23	urophorphyrin methylase 1	Arabidopsis thaliana	165-169
29472934-1	2017	Siroheme, an iron-containing tetrapyrrole, is the prosthetic group of nitrite reductase (NiR) and sulfite reductase (SiR); it is synthesized from uroporphyrinogen III, an intermediate of chlorophyll biosynthesis, and is required for nitrogen (N) and sulfur (S) assimilation.	Nitrogen	233-241	sulfite reductase	Arabidopsis thaliana	98-115
29472934-1	2017	Siroheme, an iron-containing tetrapyrrole, is the prosthetic group of nitrite reductase (NiR) and sulfite reductase (SiR); it is synthesized from uroporphyrinogen III, an intermediate of chlorophyll biosynthesis, and is required for nitrogen (N) and sulfur (S) assimilation.	Nitrogen	233-241	sulfite reductase	Arabidopsis thaliana	117-120
29719608-6	2018	Mechanistically, beta3GnT8 modulated the N-glycosylation patterns of CD147 and altered the polylactosamine structures in HCC cells by physically interacting with CD147.	Nitrogen	41-42	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	Homo sapiens	17-26
30504678-0	2018	Asiatic Acid, Corosolic Acid, and Maslinic Acid Interfere with Intracellular Trafficking and N-Linked Glycosylation of Intercellular Adhesion Molecule-1.	Nitrogen	93-94	intercellular adhesion molecule 1	Homo sapiens	119-152
30966070-1	2017	The processability of injection molding ultra-high molecular weight polyethylene (UHMWPE) was improved by introducing supercritical nitrogen (scN2) or supercritical carbon dioxide (scCO2) into the polymer melt, which decreased its viscosity and injection pressure while reducing the risk of degradation.	Nitrogen	132-140	growth factor independent 1 transcriptional repressor	Homo sapiens	142-146
28662471-2	2017	TdT can catalyze the deoxycytidine triphosphate (dCTP) to the 3"-OH terminus of single-stranded DNA (ssDNA) with no template; then, in the presence of Ag(I), TdT-generated C-rich DNA sequence was employed for the synthetic template of AgNCs because of the formed complexes of nitrogen atoms of cytosine based with silver atoms.	Nitrogen	276-284	DNA nucleotidylexotransferase	Homo sapiens	0-3
28662471-2	2017	TdT can catalyze the deoxycytidine triphosphate (dCTP) to the 3"-OH terminus of single-stranded DNA (ssDNA) with no template; then, in the presence of Ag(I), TdT-generated C-rich DNA sequence was employed for the synthetic template of AgNCs because of the formed complexes of nitrogen atoms of cytosine based with silver atoms.	Nitrogen	276-284	DNA nucleotidylexotransferase	Homo sapiens	158-161
29042437-7	2017	A signal peptide-deleted Mid1 protein, Mid1DeltaN23, was N-glycosylated and retained Ca2+ influx activity through Cch1.	Nitrogen	48-49	Mid1p	Saccharomyces cerevisiae S288C	25-29
29042437-7	2017	A signal peptide-deleted Mid1 protein, Mid1DeltaN23, was N-glycosylated and retained Ca2+ influx activity through Cch1.	Nitrogen	48-49	Cch1p	Saccharomyces cerevisiae S288C	114-118
29042437-8	2017	Moreover, an N-terminal truncation analysis revealed that even truncated Mid1 lacking 209 N-terminal amino acid residues was N-glycosylated and maintained Ca2+ influx activity.	Nitrogen	13-14	Mid1p	Saccharomyces cerevisiae S288C	73-77
29042437-9	2017	A 219-amino-acid-truncated Mid1 protein lost this activity but was still N-glycosylated.	Nitrogen	73-74	Mid1p	Saccharomyces cerevisiae S288C	27-31
29042437-10	2017	In the sec71Delta and sec72Delta single mutants defective in the post-translational protein transport into the endoplasmic reticulum (ER), Mid1DeltaN23 could not mediate Ca2+ influx and did not undergo N-glycosylation, whereas wild-type Mid1 exhibited normal Ca2+ influx activity and N-glycosylation in these mutants.	Nitrogen	202-203	Mid1p	Saccharomyces cerevisiae S288C	139-143
29232847-2	2017	For this reason, a small library of natural and synthetic nitrogen containing cyclic derivatives was assayed as activators of four human isoforms of carbonic anhydrase (hCA I, II, IV and VII).	Nitrogen	58-66	cytochrome P450 family 24 subfamily A member 1	Homo sapiens	169-190
28910647-2	2017	Three semi-continuously stirred anaerobic reactors performed well over the whole study period under mesophilic conditions, especially in experimental group (R-2) when accommodated from acclimation period which the maximum total ammonia nitrogen (TAN) and free ammonia nitrogen (FAN) increased to 4921 and 2996mg/L, respectively.	Nitrogen	236-244	CD1e molecule	Homo sapiens	157-160
28910647-2	2017	Three semi-continuously stirred anaerobic reactors performed well over the whole study period under mesophilic conditions, especially in experimental group (R-2) when accommodated from acclimation period which the maximum total ammonia nitrogen (TAN) and free ammonia nitrogen (FAN) increased to 4921 and 2996mg/L, respectively.	Nitrogen	268-276	CD1e molecule	Homo sapiens	157-160
28777988-2	2017	The optimal nitrogen removal could be achieved when the influent glucose concentration was 56.4mgL-1.	Nitrogen	12-20	LLGL scribble cell polarity complex component 1	Homo sapiens	95-100
28912343-2	2017	Accordingly, in primary nitrogen sources such as glutamine, BAT1 expression is induced, supporting Bat1-dependent valine-isoleucine-leucine (VIL) biosynthesis, while BAT2 expression is repressed.	Nitrogen	24-32	branched-chain-amino-acid transaminase BAT1	Saccharomyces cerevisiae S288C	60-64
28912343-2	2017	Accordingly, in primary nitrogen sources such as glutamine, BAT1 expression is induced, supporting Bat1-dependent valine-isoleucine-leucine (VIL) biosynthesis, while BAT2 expression is repressed.	Nitrogen	24-32	branched-chain-amino-acid transaminase BAT1	Saccharomyces cerevisiae S288C	99-103
28972750-6	2017	DFT calculations show that facile insertion of the C(aryl)-N bond by chromium(0) can take place in a high-spin quintet (S = 2) ground state, whereas the lower-spin singlet (S = 0) and triplet (S = 1) states are inaccessible in energy.	Nitrogen	59-60	spindlin 1	Homo sapiens	106-110
28972750-6	2017	DFT calculations show that facile insertion of the C(aryl)-N bond by chromium(0) can take place in a high-spin quintet (S = 2) ground state, whereas the lower-spin singlet (S = 0) and triplet (S = 1) states are inaccessible in energy.	Nitrogen	59-60	spindlin 1	Homo sapiens	159-163
28972750-7	2017	It was found that both donation of the sole paired d electrons in the d6 shell of high-spin chromium(0) to the antibonding orbital of the C(aryl)-N bond and the nitrogen ligating interaction to the metal center with its lone pair play important roles in the cleavage of the C(aryl)-N bond by the zerovalent chromium species.	Nitrogen	146-147	spindlin 1	Homo sapiens	87-91
28972750-7	2017	It was found that both donation of the sole paired d electrons in the d6 shell of high-spin chromium(0) to the antibonding orbital of the C(aryl)-N bond and the nitrogen ligating interaction to the metal center with its lone pair play important roles in the cleavage of the C(aryl)-N bond by the zerovalent chromium species.	Nitrogen	161-169	spindlin 1	Homo sapiens	87-91
28972750-7	2017	It was found that both donation of the sole paired d electrons in the d6 shell of high-spin chromium(0) to the antibonding orbital of the C(aryl)-N bond and the nitrogen ligating interaction to the metal center with its lone pair play important roles in the cleavage of the C(aryl)-N bond by the zerovalent chromium species.	Nitrogen	282-283	spindlin 1	Homo sapiens	87-91
28718966-4	2017	Initially, catalyst Ag2 CO3 coordinates preferentially with internal N atom of TMS-N3 to assist water as hydrogen source and proton-shuttle in facilitating HN3 formation.	Nitrogen	69-70	MT-RNR2 like 3 (pseudogene)	Homo sapiens	156-159
28818378-0	2017	NSR1/MYR2 is a negative regulator of ASN1 expression and its possible involvement in regulation of nitrogen reutilization in Arabidopsis.	Nitrogen	99-107	Homeodomain-like superfamily protein	Arabidopsis thaliana	5-9
28691317-2	2017	The 6FDA-DAT1-OH polyimide is thermally stable up to 440  C, shows excellent solubility in polar solvents, and has moderately high Brunauer-Teller-Emmett (BET) surface area of 160 m2 g-1 , as determined by nitrogen adsorption at -196  C. Hydroxyl functionalization applied to the rigid 3D triptycene-based diamine building block results in a polyimide that exhibits moderate pure-gas CO2 permeability of 70 Barrer combined with high CO2 /CH4 selectivity of 50.	Nitrogen	206-214	solute carrier family 6 member 3	Homo sapiens	9-13
28809966-0	2017	Template-assisted photodimerization of N-unprotected uracil derivatives: selective formation of the cis-syn photodimer.	Nitrogen	39-40	synemin	Homo sapiens	104-107
28617578-3	2017	We establish that MUC16 oncogenic effects are mediated through MGAT5-dependent N-glycosylation of two specific asparagine sites within its 58 amino acid ectodomain.	Nitrogen	79-80	mucin 16, cell surface associated	Homo sapiens	18-23
28808255-5	2017	In vivo infusion of 15N-glutamine in obese mouse models of PDA demonstrates enhanced nitrogen flux into the urea cycle and infusion of 15N-arginine shows that Arg2 loss causes significant ammonia accumulation that results from the shunting of arginine catabolism into alternative nitrogen repositories.	Nitrogen	280-288	arginase type II	Mus musculus	159-163
28794453-10	2017	According to MOB, the catchment with dominant coniferous coverage that mostly consisted of plantation with old tree age tended to have strong sensitivity of nitrate concentrations to N deposition loading.	Nitrogen	183-184	sphingomyelin synthase 1	Homo sapiens	13-16
28747680-5	2017	Progressive deletion of three demonstrated N-linked sites in EphA4 progressively increased in vivo half-life such that the triple mutant protein showed dramatically improved pharmacokinetic characteristics.	Nitrogen	43-44	EPH receptor A4	Homo sapiens	61-66
28700571-3	2017	Although Env can tolerate a high degree of mutation in five variable regions (V1-V5), and also at N-linked glycosylation sites that contribute roughly half the mass of Env, the functional sites for recognition of receptor CD4 and co-receptor CXCR4/CCR5 are conserved and essential for viral fitness.	Nitrogen	98-99	endogenous retrovirus group K member 20	Homo sapiens	9-12
28700571-3	2017	Although Env can tolerate a high degree of mutation in five variable regions (V1-V5), and also at N-linked glycosylation sites that contribute roughly half the mass of Env, the functional sites for recognition of receptor CD4 and co-receptor CXCR4/CCR5 are conserved and essential for viral fitness.	Nitrogen	98-99	endogenous retrovirus group K member 20	Homo sapiens	168-171
28569297-4	2017	The multiboron catalyst tamed previously intractable nitrogen nucleophiles, allowing for the short synthesis of a factor Xa inhibitor by catalyzing two consecutive nitrogen acylations in the same pot.	Nitrogen	53-61	coagulation factor X	Homo sapiens	114-123
28569297-4	2017	The multiboron catalyst tamed previously intractable nitrogen nucleophiles, allowing for the short synthesis of a factor Xa inhibitor by catalyzing two consecutive nitrogen acylations in the same pot.	Nitrogen	164-172	coagulation factor X	Homo sapiens	114-123
28685058-6	2017	Similarly, a higher T/N ratio, which is the ratio of CDC34 expression in HCCs to that in non-tumorous tissues, was significantly associated with favorable features, such as a lower indocyanin green retention rate after 15 min (ICG15R), reduced alpha-fetoprotein and smaller tumor size.	Nitrogen	22-23	cell division cycle 34, ubiqiutin conjugating enzyme	Homo sapiens	53-58
28357470-3	2017	We show that (i) BMPR1A and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A.	Nitrogen	147-148	bone morphogenetic protein receptor type 1A	Homo sapiens	17-23
28357470-3	2017	We show that (i) BMPR1A and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A.	Nitrogen	147-148	bone morphogenetic protein receptor type 1A	Homo sapiens	136-142
28357470-3	2017	We show that (i) BMPR1A and the ubiquitous isoform of BMPR1B differed in mode of translocation into the endoplasmic reticulum; and (ii) BMPR1A was N-glycosylated while BMPR1B was not, resulting in greater efficiency of processing and plasma membrane expression of BMPR1A.	Nitrogen	147-148	bone morphogenetic protein receptor type 1A	Homo sapiens	136-142
28442581-9	2017	The present results indicate that behavioral antagonist effects of the N-substituted BZT analogs are specific for abused drugs acting at the DAT and further suggest that sigmaR antagonism contributes to those actions.	Nitrogen	71-72	solute carrier family 6 member 3	Homo sapiens	141-144
28554476-0	2017	Corrigendum to "Challenges to develop nitrogen-fixing cereals by direct nif-gene transfer" [Plant Sci.	Nitrogen	38-46	S100 calcium binding protein A9	Homo sapiens	72-75
28487369-0	2017	N-Glycosylation affects the stability and barrier function of the MUC16 mucin.	Nitrogen	0-1	mucin 16, cell surface associated	Homo sapiens	66-71
28662078-2	2017	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosamine phosphotransferase (GPT), the protein encoded by DPAGT1, is an endoplasmic reticulum (ER)-resident protein involved in an initial step in the N-glycosylation pathway.	Nitrogen	4-5	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	112-118
30970932-6	2017	The results indicated that compared to oxygen plasma, nitrogen plasma treatment produced an anti-inflammatory effect on the collagen film by reducing the initial activation of monocytes and macrophages, which led to a lower production of pro-inflammatory cytokines IL-1beta and TNFalpha, and higher production of anti-inflammatory cytokine IL-10.	Nitrogen	54-62	interleukin 10	Homo sapiens	340-345
27865927-7	2017	Congruently, Ca2+ influx via SOCE in HEK293 cells co-expressing Orai1 and STIM1 was diminished when N-glycosylation was blocked by introducing Asn131Gln and Asn171Gln mutations.	Nitrogen	100-101	ORAI calcium release-activated calcium modulator 1	Homo sapiens	64-69
27864899-4	2017	By generating and over-expressing N-glycosylation-deficient N-cadherin mutants in the human glioma cell lines SHG66 and U87, we found that mutation of N402 but not of the other potentially N-glycosylated residues destabilized N-cadherin and led to its ubiquitylation and subsequent proteasomal degradation.	Nitrogen	34-35	cadherin 2	Homo sapiens	60-70
27864899-6	2017	Our findings reveal that N-glycosylation controls N-cadherin stability and plays a role in glioma migration.	Nitrogen	25-26	cadherin 2	Homo sapiens	50-60
28273364-2	2017	Under nitrogen deprivation, the green alga C. reinhardtii showed substantial triacylglycerol (TAG) accumulation and up-regulation of a gene, GPD2, encoding a multidomain enzyme with a putative phosphoserine phosphatase (PSP) motif fused to glycerol-3-phosphate dehydrogenase (GPD) domains.	Nitrogen	6-14	uncharacterized protein	Chlamydomonas reinhardtii	240-274
28545421-1	2017	BACKGROUND: The blood urea nitrogen to creatinine ratio (BCR) has been used since the early 1940s to help clinicians differentiate between prerenal acute kidney injury (PR AKI) and intrinsic AKI (I AKI).	Nitrogen	27-35	BCR activator of RhoGEF and GTPase	Homo sapiens	57-60
28581809-3	2017	Here, we propose a scheme to detect the charge recombination rate in a radical pair reaction under ambient conditions by using single nitrogen-vacancy center spin in diamond.	Nitrogen	134-142	spindlin 1	Homo sapiens	158-162
28168313-3	2017	By applying different nitrogen sources and air supply conditions in batch culture, organic nitrogen sources and microaerobic condition were decided to be more favorable for both cell growth and ethanol production of the BSPT15-M3 strain than the control S. cerevisiae BY4741 strain expressing the SPT15 gene (BSPT15wt).	Nitrogen	22-30	TATA-binding protein	Saccharomyces cerevisiae S288C	221-226
28168313-3	2017	By applying different nitrogen sources and air supply conditions in batch culture, organic nitrogen sources and microaerobic condition were decided to be more favorable for both cell growth and ethanol production of the BSPT15-M3 strain than the control S. cerevisiae BY4741 strain expressing the SPT15 gene (BSPT15wt).	Nitrogen	91-99	TATA-binding protein	Saccharomyces cerevisiae S288C	221-226
28606216-1	2017	Although high dose n-3 PUFA supplementation reduces exercise- and hyperpnoea-induced bronchoconstriction (EIB/HIB), there are concurrent issues with cost, compliance and gastrointestinal discomfort.	Nitrogen	19-20	pumilio RNA binding family member 3	Homo sapiens	23-27
28660107-9	2017	IONM significantly decreased in NCR and CR groups than in N group (P &lt; .05).	Nitrogen	2-3	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	32-35
28315683-4	2017	The results showed that Ad-klotho significantly reduced serum creatinine (Scr) and blood urea nitrogen (BUN) caused by CsA, and significantly increased creatinine clearance.	Nitrogen	94-102	klotho	Homo sapiens	27-33
28351631-0	2017	Fluorescent nitrogen and sulfur co-doped carbon dots from casein and their applications for sensitive detection of Hg2+ and biothiols and cellular imaging.	Nitrogen	12-20	polycystin 1, transient receptor potential channel interacting pseudogene 2	Homo sapiens	115-118
28329445-4	2017	Our sensor is the electronic spin of a diamond nitrogen-vacancy center attached to a scanning tip and operated under ambient conditions.	Nitrogen	47-55	spindlin 1	Homo sapiens	29-33
28430485-1	2017	We report coherent coupling between two macroscopically separated nitrogen-vacancy electron spin ensembles in a cavity quantum electrodynamics system.	Nitrogen	66-74	spindlin 1	Homo sapiens	92-96
28032637-0	2017	Nitrogen Limitation Adaptation (NLA) is involved in source-to-sink remobilization of nitrate by mediating the degradation of NRT1.7 in Arabidopsis.	Nitrogen	0-8	nitrate transporter 1.1	Arabidopsis thaliana	125-129
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	14-22	GRAS family transcription factor family protein	Arabidopsis thaliana	153-156
28275852-6	2017	Moreover, the nitrogen deficiency-induced anthocyanin accumulation and biosynthesis gene expressions were impaired in the loss-of-function mutant gai-t6/rga-t2/rgl1-1/rgl2-1/rgl3-1 (della) but enhanced in the GA-insensitive mutant gai, suggesting that DELLA proteins, known as repressors of GA signaling, are necessary for fully induction of nitrogen deficiency-driven anthocyanin biosynthesis.	Nitrogen	342-350	GRAS family transcription factor family protein	Arabidopsis thaliana	153-156
28137749-1	2017	The soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) protein syntaxin-1 adopts a closed conformation when bound to Munc18-1, preventing binding to synaptobrevin-2 and SNAP-25 to form the ternary SNARE complex.	Nitrogen	12-13	syntaxin binding protein 1	Homo sapiens	144-152
27976829-2	2017	The placement of the N-Boc-amino groups in the two stereoisomers in either pseudo-equatorial or pseudo-axial positions renders the molecules conformationally locked, with N-Boc-protected gamma-aminobutyric acid (GABA) embedded within the bicyclic core.	Nitrogen	21-22	BOC cell adhesion associated, oncogene regulated	Homo sapiens	23-26
27976829-2	2017	The placement of the N-Boc-amino groups in the two stereoisomers in either pseudo-equatorial or pseudo-axial positions renders the molecules conformationally locked, with N-Boc-protected gamma-aminobutyric acid (GABA) embedded within the bicyclic core.	Nitrogen	21-22	BOC cell adhesion associated, oncogene regulated	Homo sapiens	173-176
27916483-7	2017	Multiple linear regression analyses revealed that alpha-Klotho and beta-Klotho levels were positively correlated with the creatinine clearance rate, and negatively correlated with the urinary albumin to creatinine ratio and randomly sampled serum levels of creatinine, blood urea nitrogen, and blood glucose.	Nitrogen	280-288	klotho	Homo sapiens	56-62
27916483-7	2017	Multiple linear regression analyses revealed that alpha-Klotho and beta-Klotho levels were positively correlated with the creatinine clearance rate, and negatively correlated with the urinary albumin to creatinine ratio and randomly sampled serum levels of creatinine, blood urea nitrogen, and blood glucose.	Nitrogen	280-288	klotho beta	Homo sapiens	67-78
28107736-6	2017	The binding modes of 12a,b and 13a,b confirmed that the major interactions with hMAO-B were established via the flexible carbonyl group of the carboxamide linkage and the electron-donating nitrogens N1 or N2 of the indazole moiety, allowing further exploration of the alkyl side chain for next step lead optimization efforts.	Nitrogen	189-198	monoamine oxidase B	Homo sapiens	80-86
28894349-1	2017	Spin-Exchange Frequencies of the Order of the Nitrogen Hyperfine Interaction: A Hypothesis.	Nitrogen	46-54	spindlin 1	Homo sapiens	0-4
31457235-5	2017	Being nitrogen-rich tetrazolate compounds, the enthalpies of combustion of 1 (-11.570 kJ g-1) and 2 (-12.186 kJ g-1) are higher than those of classical EMs, RDX and HMX, and they possess high positive heats of formation.	Nitrogen	6-14	proline rich protein BstNI subfamily 3	Homo sapiens	89-99
31457235-5	2017	Being nitrogen-rich tetrazolate compounds, the enthalpies of combustion of 1 (-11.570 kJ g-1) and 2 (-12.186 kJ g-1) are higher than those of classical EMs, RDX and HMX, and they possess high positive heats of formation.	Nitrogen	6-14	radixin	Homo sapiens	157-160
28017611-0	2017	Regulation of Differentiation of Nitrogen-Fixing Bacteria by Microsymbiont Targeting of Plant Thioredoxin s1.	Nitrogen	33-41	trxA2	Sinorhizobium meliloti	94-105
29441891-6	2017	Dose-dependent increases in serum markers of hepato-renal function (serum aminotransferases and blood urea nitrogen) were observed following administration of nPt1, whereas nPt8 had no effect, even at 20 mg/kg.	Nitrogen	107-115	solute carrier family 17 (sodium phosphate), member 1	Mus musculus	159-163
28077952-4	2017	RESULTS: We show that Irr1 protein is enriched in the cytoplasm upon arrest of yeast cells in G1 phase following nitrogen starvation, diauxic shift or alpha-factor action, and also during normal cell cycle.	Nitrogen	113-121	Irr1p	Saccharomyces cerevisiae S288C	22-26
29354263-4	2017	The approach adopted here was deacetylation of the N-acetyl group and selective sulfation on the C6-OH on the HA polymer, which form critical interactions with the CD44 active site.	Nitrogen	51-52	CD44 molecule (Indian blood group)	Homo sapiens	164-168
28012418-6	2017	The accumulation of N2 in cancer cells was in consistent with the overexpression of glucose transporter GLUT-1 in these cells.	Nitrogen	20-22	solute carrier family 2 member 1	Homo sapiens	104-110
28012418-7	2017	The cellular uptake of N2 was then confirmed to be dependent on GLUT-1, which was evidenced by the decreased uptake of N2 in the presence of d-glucose or GLUT-1 inhibitor phloretin.	Nitrogen	23-25	solute carrier family 2 member 1	Homo sapiens	64-70
28012418-7	2017	The cellular uptake of N2 was then confirmed to be dependent on GLUT-1, which was evidenced by the decreased uptake of N2 in the presence of d-glucose or GLUT-1 inhibitor phloretin.	Nitrogen	23-25	solute carrier family 2 member 1	Homo sapiens	154-160
28012418-7	2017	The cellular uptake of N2 was then confirmed to be dependent on GLUT-1, which was evidenced by the decreased uptake of N2 in the presence of d-glucose or GLUT-1 inhibitor phloretin.	Nitrogen	119-121	solute carrier family 2 member 1	Homo sapiens	64-70
27923447-7	2017	Moreover, fat-1 transgenic mice treated with N-IgY showed significant downregulation of genes involved in cholesterol-induced hepatic stellate cell activation (Tgfb1, Tlr4, Col1a1, Col1a2, and Timp2).	Nitrogen	45-46	FAT atypical cadherin 1	Mus musculus	10-15
28178702-7	2017	The silencing of ALG13-is2 by specific siRNAs induces an altered N-linked glycosylation pattern of nephrin, as demonstrated by the presence of an additional immunostaining band of about 130 kD.	Nitrogen	42-43	NPHS1 adhesion molecule, nephrin	Homo sapiens	99-106
28027835-3	2017	Conversely, Nitrogen-14 (spin 1) NQR is much less sensitive because its resonances frequencies are below 6MHz.	Nitrogen	12-20	spindlin 1	Homo sapiens	25-31
27384988-0	2016	Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated.	Nitrogen	66-67	ribosomal protein S3	Homo sapiens	0-20
27384988-0	2016	Ribosomal protein S3 (rpS3) secreted from various cancer cells is N-linked glycosylated.	Nitrogen	66-67	ribosomal protein S3	Homo sapiens	22-26
27384988-7	2016	N-linked glycosylation of rpS3 was confirmed as necessary for rpS3 secretion into culture media via the ER-Golgi dependent pathway.	Nitrogen	0-1	ribosomal protein S3	Homo sapiens	26-30
27384988-7	2016	N-linked glycosylation of rpS3 was confirmed as necessary for rpS3 secretion into culture media via the ER-Golgi dependent pathway.	Nitrogen	0-1	ribosomal protein S3	Homo sapiens	62-66
27384988-11	2016	The results indicate that the Asn 165 residue of rpS3 is a critical site for N-linked glycosylation and passage through the ER-Golgi secretion pathway.	Nitrogen	77-78	ribosomal protein S3	Homo sapiens	49-53
27612916-6	2016	This amino acid change was predicted to create a putative N-glycosylation motif NX(S/T) subsequently validated upon endoglycosidase H treatment of microsomal fractions and inhibition of N-glycosylation of endogenously produced UGT2B7 with tunicamycin in human embryonic kidney (HEK293) cells.	Nitrogen	58-59	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	227-233
27612916-6	2016	This amino acid change was predicted to create a putative N-glycosylation motif NX(S/T) subsequently validated upon endoglycosidase H treatment of microsomal fractions and inhibition of N-glycosylation of endogenously produced UGT2B7 with tunicamycin in human embryonic kidney (HEK293) cells.	Nitrogen	80-81	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	227-233
27693235-4	2016	The dDad1 protein, an orthologue of mammalian Dad1, was found to be crucial for protein N-glycosylation in developing tissues.	Nitrogen	88-89	defender against cell death 1	Homo sapiens	5-9
27565712-0	2016	Importance of membrane-proximal N-glycosylation on integrin beta1 in its activation and complex formation.	Nitrogen	32-33	integrin subunit beta 1	Homo sapiens	51-65
27565712-2	2016	Here, we present evidence that the membrane-proximal N-glycosylation on integrin beta1 could positively regulate cell migration by promoting beta1 activation.	Nitrogen	53-54	integrin subunit beta 1	Homo sapiens	72-86
27565712-6	2016	Further study on the regulatory mechanisms suggested that membrane-proximal N-glycosylation is critical for intermolecular interactions between integrin beta1 and other cell membrane proteins, such as syndecan-4 and epidermal growth factor receptor.	Nitrogen	76-77	integrin subunit beta 1	Homo sapiens	144-158
27565712-9	2016	Importance of membrane-proximal N-glycosylation on integrin beta1 in its activation and complex formation.	Nitrogen	32-33	integrin subunit beta 1	Homo sapiens	51-65
27467133-5	2016	n-3 PUFA intake was estimated using red blood cell nitrogen stable isotope ratios.	Nitrogen	51-59	pumilio RNA binding family member 3	Homo sapiens	4-8
27541496-0	2016	N availability modulates the role of NPF3.1, a gibberellin transporter, in GA-mediated phenotypes in Arabidopsis.	Nitrogen	0-1	Major facilitator superfamily protein	Arabidopsis thaliana	37-43
27887615-11	2016	When driven by the intronic promoters of ACC1 and LDP1 (ACC1in and LDP1in promoter, respectively), the reporter gene expression were up-regulated by nitrogen starvation, independent of de novo oil biosynthesis and accumulation.	Nitrogen	149-157	acetyl-CoA carboxylase ACC1	Saccharomyces cerevisiae S288C	41-45
27887615-11	2016	When driven by the intronic promoters of ACC1 and LDP1 (ACC1in and LDP1in promoter, respectively), the reporter gene expression were up-regulated by nitrogen starvation, independent of de novo oil biosynthesis and accumulation.	Nitrogen	149-157	acetyl-CoA carboxylase ACC1	Saccharomyces cerevisiae S288C	56-60
27790232-1	2016	The next advance in field crop productivity will likely need to come from improving crop use efficiency of resources (e.g., light, water, and nitrogen), aspects of which are closely linked with overall crop photosynthetic efficiency.	Nitrogen	142-150	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	26-30
27790232-1	2016	The next advance in field crop productivity will likely need to come from improving crop use efficiency of resources (e.g., light, water, and nitrogen), aspects of which are closely linked with overall crop photosynthetic efficiency.	Nitrogen	142-150	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	84-88
27627613-1	2016	Here, we report a hierarchical Co3ZnC/carbon nanotube-inserted nitrogen-doped carbon concave-polyhedrons synthesized by direct pyrolysis of bimetallic zeolitic imidazolate framework precursors under a flow of Ar/H2 and subsequent calcination for both high-performance rechargeable Li-ion and Na-ion batteries.	Nitrogen	63-71	ADP-ribosylhydrolase like 1	Homo sapiens	209-214
26865057-6	2016	The DCD degraded fast during the thermophilic phase, as the nitrification will be inhibited by the high temperature and high free ammonia content in this stage, the DCD was suggested to be applied in the maturing periods by 2.5% of initial nitrogen.	Nitrogen	240-248	dermcidin	Homo sapiens	4-7
26865057-6	2016	The DCD degraded fast during the thermophilic phase, as the nitrification will be inhibited by the high temperature and high free ammonia content in this stage, the DCD was suggested to be applied in the maturing periods by 2.5% of initial nitrogen.	Nitrogen	240-248	dermcidin	Homo sapiens	165-168
27665743-5	2016	Presence of N-glycosylated ENPP3 in receptive phase uterine fluid in women confirms its regulation by progesterone and makes it possible to use in a non-invasive test of endometrial receptivity.	Nitrogen	12-13	ectonucleotide pyrophosphatase/phosphodiesterase 3	Homo sapiens	27-32
27641064-0	2016	N-Glycosylation of integrin alpha5 acts as a switch for EGFR-mediated complex formation of integrin alpha5beta1 to alpha6beta4.	Nitrogen	0-1	integrin subunit alpha 5	Bos taurus	19-34
27641064-2	2016	We previously reported that the N-glycosylations of the calf domain on integrin alpha5 (S3-5,10-14) are essential for its inhibitory effect on EGFR signaling in regulating cell proliferation.	Nitrogen	32-33	integrin subunit alpha 5	Bos taurus	71-86
27126996-8	2016	In line with this, CP-d/n-ATF5-S1 synergistically enhanced tumor cell apoptosis induced by the BH3-mimetic ABT263 and the death ligand TRAIL.	Nitrogen	1-2	activating transcription factor 5	Homo sapiens	26-30
27126996-10	2016	Finally, the combination treatment of CP-d/n-ATF5-S1 and ABT263 significantly reduced tumor growth in vivo more efficiently than each reagent on its own.	Nitrogen	2-3	activating transcription factor 5	Homo sapiens	45-49
26592446-5	2016	Cluster analysis of super-resolution data indicates that N-linked glycosylation and palmitoylation of CD82 are both critical modifications that control the microdomain organization of CD82 as well as the nanoscale clustering of associated adhesion protein, N-cadherin.	Nitrogen	57-58	CD82 molecule	Homo sapiens	184-188
26592446-5	2016	Cluster analysis of super-resolution data indicates that N-linked glycosylation and palmitoylation of CD82 are both critical modifications that control the microdomain organization of CD82 as well as the nanoscale clustering of associated adhesion protein, N-cadherin.	Nitrogen	57-58	cadherin 2	Homo sapiens	257-267
27444263-2	2016	This article reports for the first time the facile preparation of N-doped TiO2 (P25 titania) in aqueous media at ambient temperature and pressure under inert conditions (Ar- and N2-purged dispersions) with 4-nitrophenol (or 4-nitrobenzaldehyde) as the nitrogen source.	Nitrogen	66-67	tubulin polymerization promoting protein	Homo sapiens	80-83
27444263-3	2016	The resulting N-doped P25 TiO2 materials were characterized by UV/Vis and X-ray photoelectron spectroscopies (XPS) that confirmed the presence of nitrogen within the photocatalyst; X-ray diffraction (XRD) techniques confirmed the crystalline phases of the doped material.	Nitrogen	146-154	tubulin polymerization promoting protein	Homo sapiens	22-25
27527129-2	2016	Quinoline-based azathilones with the side chain N-atom in the meta-position to the C15 atom in the macrocycle are highly potent inhibitors of cancer cell growth in vitro.	Nitrogen	48-49	placenta associated 8	Homo sapiens	83-86
27527129-3	2016	In contrast, shifting the quinoline nitrogen to the position para to C15 leads to a ca.	Nitrogen	36-44	placenta associated 8	Homo sapiens	69-72
27269511-1	2016	Genome analysis of fourteen mimosoid and four papilionoid beta-rhizobia together with fourteen reference alpha-rhizobia for both nodulation (nod) and nitrogen-fixing (nif/fix) genes has shown phylogenetic congruence between 16S rRNA/MLSA (combined 16S rRNA gene sequencing and multilocus sequence analysis) and nif/fix genes, indicating a free-living diazotrophic ancestry of the beta-rhizobia.	Nitrogen	150-158	S100 calcium binding protein A9	Homo sapiens	167-170
27294781-0	2016	N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Botulinum neurotoxin serotype A1 (BoNT/A1), a licensed drug widely used for medical and cosmetic applications, exerts its action by invading motoneurons.	Nitrogen	0-1	synaptic vesicle glycoprotein 2A	Homo sapiens	26-29
27223070-1	2016	BACKGROUND: N-acetyltransferase 2 (NAT2) is involved in both carcinogen detoxification through hepatic N-acetylation and carcinogen activation through local O-acetylation.	Nitrogen	8-9	N-acetyltransferase 2	Homo sapiens	12-33
27223070-1	2016	BACKGROUND: N-acetyltransferase 2 (NAT2) is involved in both carcinogen detoxification through hepatic N-acetylation and carcinogen activation through local O-acetylation.	Nitrogen	8-9	N-acetyltransferase 2	Homo sapiens	35-39
27223070-4	2016	RESULTS: The CMR, a functional measure of hepatic N-acetylation, was significantly reduced in a dose-dependent manner among both cases and controls possessing the SNP-inferred NAT2 slow acetylation status (all P-values&lt;5.0x10-10).	Nitrogen	50-51	N-acetyltransferase 2	Homo sapiens	176-180
27293103-9	2016	In addition, NLP7 improves plant growth and nitrogen use in transgenic tobacco (Nicotiana tabacum).	Nitrogen	44-52	NIN like protein 7	Arabidopsis thaliana	13-17
27293103-10	2016	Our results demonstrate that NLP7 significantly improves plant growth under both nitrogen-poor and -rich conditions by coordinately enhancing nitrogen and carbon assimilation and sheds light on crop improvement.	Nitrogen	81-89	NIN like protein 7	Arabidopsis thaliana	29-33
27293103-10	2016	Our results demonstrate that NLP7 significantly improves plant growth under both nitrogen-poor and -rich conditions by coordinately enhancing nitrogen and carbon assimilation and sheds light on crop improvement.	Nitrogen	142-150	NIN like protein 7	Arabidopsis thaliana	29-33
26701645-4	2016	By LC-MS/MS analysis of human tyrosinase expressed in a melanoma cell, we show that all seven sites of tyrosinase are at least partially N-glycosylated.	Nitrogen	137-138	tyrosinase	Homo sapiens	30-40
26701645-4	2016	By LC-MS/MS analysis of human tyrosinase expressed in a melanoma cell, we show that all seven sites of tyrosinase are at least partially N-glycosylated.	Nitrogen	137-138	tyrosinase	Homo sapiens	103-113
26701645-5	2016	Using human CD8+ T-cell clones specific for the tyrosinase epitope YMDGTMSQV (369-377), including an N-glycosylation site, we found that transfectants of single and triple N-glycosylation mutants are recognized by specific T cells.	Nitrogen	172-173	tyrosinase	Homo sapiens	48-58
26701645-6	2016	Importantly, single, triple, and the aglycosylated tyrosinase mutants lacking the epitope located N-glycosylation site (N371D) were able to trigger higher CD8+ T-cell activation.	Nitrogen	98-99	tyrosinase	Homo sapiens	51-61
26232394-11	2016	Indeed, we have found that leptin robustly suppresses the OFQ/N-induced activation of GIRK channels in POMC neurons.	Nitrogen	62-63	proopiomelanocortin	Rattus norvegicus	103-107
27193936-4	2016	Here we show the spin echo of a degenerate spin subsystem, which is geometrically controlled via a mediating state split by the crystal field, in a nitrogen vacancy centre in diamond.	Nitrogen	148-156	spindlin 1	Homo sapiens	17-21
27193936-4	2016	Here we show the spin echo of a degenerate spin subsystem, which is geometrically controlled via a mediating state split by the crystal field, in a nitrogen vacancy centre in diamond.	Nitrogen	148-156	spindlin 1	Homo sapiens	43-47
27016566-0	2016	Relating Carbon and Nitrogen Isotope Effects to Reaction Mechanisms during Aerobic or Anaerobic Degradation of RDX (Hexahydro-1,3,5-Trinitro-1,3,5-Triazine) by Pure Bacterial Cultures.	Nitrogen	20-28	radixin	Homo sapiens	111-114
27016566-1	2016	UNLABELLED: Kinetic isotopic fractionation of carbon and nitrogen during RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) biodegradation was investigated with pure bacterial cultures under aerobic and anaerobic conditions.	Nitrogen	57-65	radixin	Homo sapiens	73-76
27016566-9	2016	IMPORTANCE: This work provides the first systematic evaluation of the isotopic fractionation of carbon and nitrogen in the organic explosive RDX during degradation by different pathways.	Nitrogen	107-115	radixin	Homo sapiens	141-144
26966273-7	2016	PAR4 Y157C was partially retained in the endoplasmic reticulum and displayed an expression pattern consistent with defective N-glycosylation.	Nitrogen	125-126	F2R like thrombin or trypsin receptor 3	Homo sapiens	0-4
26913793-1	2016	Glutamine synthetase (GS) and asparagine synthetase (AS) are proposed to have important function in plant nitrogen (N) remobilization, but their roles under drought stress are not well defined.	Nitrogen	106-114	LOC100856906	Zea mays	30-51
26913793-1	2016	Glutamine synthetase (GS) and asparagine synthetase (AS) are proposed to have important function in plant nitrogen (N) remobilization, but their roles under drought stress are not well defined.	Nitrogen	106-114	LOC100856906	Zea mays	53-55
26913793-2	2016	In this study, the expression dynamics of GS and AS genes were analyzed in two maize varieties (ZD958 and NH101) in relation to post-silking drought stress induced nitrogen partitioning.	Nitrogen	164-172	LOC100856906	Zea mays	49-51
26913793-9	2016	Drought stress altered maize N partitioning at the whole-plant level, and the up-regulation of GS and AS genes may contribute to the higher leaf nitrogen remobilization when exposed to drought treatments.	Nitrogen	145-153	LOC100856906	Zea mays	102-104
27088325-3	2016	Here we report X-ray crystal structures of the Mep2 orthologues from Saccharomyces cerevisiae and Candida albicans and show that under nitrogen-sufficient conditions the transporters are not phosphorylated and present in closed, inactive conformations.	Nitrogen	135-143	ammonium permease MEP2	Saccharomyces cerevisiae S288C	47-51
26992746-4	2016	The annual load of nitrogen contained in the food waste corresponds to 52% of load of nitrogen from the ship-generated sewage.	Nitrogen	19-27	inositol polyphosphate-5-phosphatase D	Homo sapiens	104-108
26992746-4	2016	The annual load of nitrogen contained in the food waste corresponds to 52% of load of nitrogen from the ship-generated sewage.	Nitrogen	86-94	inositol polyphosphate-5-phosphatase D	Homo sapiens	104-108
26654979-10	2016	Among the peptides/proteins identified, ACSL, ACOX2, MTP, and THIKB contribute to regulation of fatty acid metabolism and ARG1, ARLY, and OAT, which regulate nitrogen and ammonia metabolism having direct relevance to ethanol-induced liver injury.	Nitrogen	158-166	lysosomal-associated protein transmembrane 4A	Mus musculus	53-56
27004849-3	2016	In particular, we observed an enrichment of mutations in genes (B3GNT2, B4GALT2, ST6GALNAC2) involved in the biosynthesis of N- and Cores 1-3 O-linked glycans in the colon, accounting for ~16% of the CRCs tested.	Nitrogen	67-68	ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	Homo sapiens	81-91
27005614-6	2016	For example, cytosolic glutamine synthetase (GS1), heat shock protein 70 (Hsp70), and chloroplastic elongation factor G (cpEF-G) were involved in pigment-related nitrogen synthesis as well as protein synthesis and processing.	Nitrogen	162-170	heat shock protein family A (Hsp70) member 4	Homo sapiens	51-72
27005614-6	2016	For example, cytosolic glutamine synthetase (GS1), heat shock protein 70 (Hsp70), and chloroplastic elongation factor G (cpEF-G) were involved in pigment-related nitrogen synthesis as well as protein synthesis and processing.	Nitrogen	162-170	heat shock protein family A (Hsp70) member 4	Homo sapiens	74-79
26989612-15	2016	The importance of nitrogen and iodine recycling in sheep was highlighted by the highly preferential expression of SLC14A1-urea (rumen), RHBG-ammonia (intestines) and SLC5A5-iodine (abomasum).	Nitrogen	18-26	sodium/iodide cotransporter	Ovis aries	166-172
26740626-0	2016	Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.	Nitrogen	98-99	secretin	Homo sapiens	117-125
26564424-8	2016	Genotypic CCR5-tropic variants were predominant (98.9%) with conservation of putative N-linked glycosylation sites in both compartments.	Nitrogen	86-87	C-C motif chemokine receptor 5	Homo sapiens	10-14
26930496-7	2016	Both the expression of key fermentative enzymes and their respective metabolites were significantly altered in ami-hcp4, with nitrogen uptake from the media also being significantly different than wild-type cells.	Nitrogen	126-134	uncharacterized protein	Chlamydomonas reinhardtii	115-119
26930496-8	2016	The results strongly suggest a role for HCP4 in regulating key fermentative and nitrogen utilization pathways.	Nitrogen	80-88	uncharacterized protein	Chlamydomonas reinhardtii	40-44
26876901-4	2016	In particular, using a combination of state-of-the-art ab-initio calculations based on hybrid density functional and many-body perturbation theory, we predicted that the negatively charged nitrogen vacancy center in piezoelectric aluminum nitride exhibits spin-triplet ground states under realistic uni- and bi-axial strain conditions; such states may be harnessed for the realization of qubits.	Nitrogen	189-197	spindlin 1	Homo sapiens	256-260
26745514-4	2016	Here, we fabricated MS-TiO2 and NS-TiO2, both of which were incorporated with the TiO2 nanoparticles (P25) to constitute the hybrid photoanode of dye-sensitized solar cells (DSSCs), and explored the effect of the lateral size (nano- and micro-) of ultrathin TiO2 nanosheets on their electron transfer and diffusion properties.	Nitrogen	32-34	tubulin polymerization promoting protein	Homo sapiens	102-105
26693208-4	2016	Additionally, unexpected emission behavior in dye systems d7 and d8 wherein the amino- derivative d7 displayed a dual emission in polar medium while the N,N-dimethyl derivative d8 and other methylated derivatives d12-d14 showed only LE emission but did not show any TICT emission.	Nitrogen	153-154	unconventional SNARE in the ER 1	Homo sapiens	213-216
26678838-8	2016	The growth assays demonstrated that the growth of the eprS mutant was somewhat lower than that of the wild-type strain in a minimal medium containing BSA as the sole carbon and nitrogen source.	Nitrogen	177-185	glutamyl-prolyl-tRNA synthetase	Mus musculus	54-58
26059044-10	2016	Altogether, our data demonstrate that plants offer an excellent tool to investigate the role of N-glycosylation on folding and activity of recombinant glycoproteins, such as IL-22.	Nitrogen	96-97	interleukin 22	Homo sapiens	174-179
26871331-2	2016	To this end, we exploit a three-level system with a Lambda configuration in the microwave domain, which consists of nuclear spin states addressed through their hyperfine coupling to the electron spin of a single nitrogen-vacancy defect in diamond.	Nitrogen	212-220	spindlin 1	Homo sapiens	124-128
26871331-2	2016	To this end, we exploit a three-level system with a Lambda configuration in the microwave domain, which consists of nuclear spin states addressed through their hyperfine coupling to the electron spin of a single nitrogen-vacancy defect in diamond.	Nitrogen	212-220	spindlin 1	Homo sapiens	195-199
26691389-0	2016	Nitrogen positional scanning in tetramines active against HIV-1 as potential CXCR4 inhibitors.	Nitrogen	0-8	C-X-C motif chemokine receptor 4	Homo sapiens	77-82
30406218-4	2016	When carbon 5 (C5) of cytosine is substituted with a nitrogen atom (N) in 5-aza-cytosine analogues, the critical beta-elimination reaction cannot proceed, which results in the permanent attachment of 5-aza-cytosine to DNMT.	Nitrogen	53-61	DNA methyltransferase 1	Homo sapiens	218-222
27313878-5	2016	Dietary n-3 polyunsaturated fatty acids (n-3 PUFAs) may exert a beneficial effect by shifting Th1/Th2 balance to a Th2 phenotype and increasing insulin sensitivity.	Nitrogen	8-9	negative elongation factor complex member C/D	Homo sapiens	94-97
26537798-7	2016	The altered N-glycosylation of TNF-alpha-treated adipocytes correlated with the regulation of specific glycosyltransferases, including the up-regulation of B4GalT5 and Ggta1 galactosyltransferases and down-regulation of ST3Gal6 sialyltransferase.	Nitrogen	12-13	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	Mus musculus	156-163
26537798-7	2016	The altered N-glycosylation of TNF-alpha-treated adipocytes correlated with the regulation of specific glycosyltransferases, including the up-regulation of B4GalT5 and Ggta1 galactosyltransferases and down-regulation of ST3Gal6 sialyltransferase.	Nitrogen	12-13	glycoprotein galactosyltransferase alpha 1, 3	Mus musculus	168-173
26632974-3	2015	Furthermore, the fused pentagon network shows an exceptionally high selectivity for H2/gas (CO, CH4, CO2, N2, et al.)	Nitrogen	106-108	relaxin 2	Homo sapiens	84-90
26483551-0	2015	Integrin alpha5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation.	Nitrogen	136-137	integrin subunit alpha 5	Bos taurus	0-15
26483551-4	2015	Here we show that integrin alpha5 functions as a negative regulator of epidermal growth factor receptor (EGFR) signaling through its N-glycosylation.	Nitrogen	133-134	integrin subunit alpha 5	Bos taurus	18-33
26483551-6	2015	However, expression of the N-glycosylation mutant integrin alpha5, S3-5, which contains fewer N-glycans, reversed the suppression of the EGFR-mediated signaling and cell proliferation.	Nitrogen	27-28	integrin subunit alpha 5	Bos taurus	50-65
26835119-5	2015	Long chain n-3 polyunsaturated fatty acids (n-3 PUFA) have multiple effects on cardiac electrophysiology, and epidemiological studies on fish oil suggest a possible use of n-3 PUFA in AF prevention.	Nitrogen	2-3	pumilio RNA binding family member 3	Homo sapiens	48-52
26835119-5	2015	Long chain n-3 polyunsaturated fatty acids (n-3 PUFA) have multiple effects on cardiac electrophysiology, and epidemiological studies on fish oil suggest a possible use of n-3 PUFA in AF prevention.	Nitrogen	2-3	pumilio RNA binding family member 3	Homo sapiens	176-180
26458842-4	2015	The results showed that each of the human proteins, CELSR1, ST3GAL5 and VSIG10, lost an ancestrally conserved N-glycosylation site following human-chimpanzee divergence.	Nitrogen	110-111	cadherin EGF LAG seven-pass G-type receptor 1	Homo sapiens	52-58
26458842-4	2015	The results showed that each of the human proteins, CELSR1, ST3GAL5 and VSIG10, lost an ancestrally conserved N-glycosylation site following human-chimpanzee divergence.	Nitrogen	110-111	V-set and immunoglobulin domain containing 10	Homo sapiens	72-78
26675329-2	2015	The hypothesis of this study was that diet with a low ratio of n-6/n-3 polyunsaturated fatty acids (PUFAs) is associated with reduced MMP13 expression in inflammatory chondrocytes in vitro and in vivo.	Nitrogen	63-64	matrix metallopeptidase 13	Rattus norvegicus	134-139
26447683-1	2015	Primary nitrogen assimilation in plants includes the reduction of nitrite to ammonium in the chloroplasts by the enzyme nitrite reductase (NiR EC:1.7.7.1) or in the plastids of non-photosynthetic organs.	Nitrogen	8-16	nitrite reductase 1	Arabidopsis thaliana	139-142
26447683-7	2015	This reveals the importance of NiR in primary nitrogen assimilation and how modification of this key enzyme affects both the nitrogen and carbon metabolism of tobacco plants.	Nitrogen	46-54	nitrite reductase 1	Arabidopsis thaliana	31-34
26447683-7	2015	This reveals the importance of NiR in primary nitrogen assimilation and how modification of this key enzyme affects both the nitrogen and carbon metabolism of tobacco plants.	Nitrogen	125-133	nitrite reductase 1	Arabidopsis thaliana	31-34
26302999-0	2015	Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype.	Nitrogen	17-18	C-X-C motif chemokine receptor 1	Homo sapiens	88-93
26523462-3	2015	The restoration of the nitrogen in a position equivalent to the purines" N7 leads to "isofunctional" behavior, as illustrated by the ability of adenosine deaminase to deaminate (tz)A as effectively as adenosine, the native substrate.	Nitrogen	23-31	adenosine deaminase	Homo sapiens	144-163
26503048-5	2015	Here we describe the rhodium-catalysed carboamination of alkenes at the same (syn) face of a double bond, initiated by a carbon-hydrogen activation event that uses enoxyphthalimides as the source of both the carbon and the nitrogen functionalities.	Nitrogen	223-231	synemin	Homo sapiens	78-81
26276083-6	2015	Studies showed the involvement of CYP1A2, CYP2B6, CYP2C19, and CYP3A4 in N-dealkylation of all three compounds and additionally CYP2D6 for lefetamine and NEDPA.	Nitrogen	73-74	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	50-57
26503599-9	2015	In male PCK rats, age-related increases in blood urea nitrogen and creatinine at 10 to 19 weeks of age were observed, and the cystic progression was more severe than that in females.	Nitrogen	54-62	phosphoenolpyruvate carboxykinase 1	Rattus norvegicus	8-11
26371233-5	2015	Overexpression of TaNAC2-5A in wheat enhanced root growth and nitrate influx rate and, hence, increased the root"s ability to acquire nitrogen.	Nitrogen	134-142	NAC domain-containing protein 2	Triticum aestivum	18-24
26371233-6	2015	Furthermore, we found that TaNAC2-5A-overexpressing transgenic wheat lines had higher grain yield and higher nitrogen accumulation in aerial parts and allocated more nitrogen in grains in a field experiment.	Nitrogen	109-117	NAC domain-containing protein 2	Triticum aestivum	27-33
26371233-6	2015	Furthermore, we found that TaNAC2-5A-overexpressing transgenic wheat lines had higher grain yield and higher nitrogen accumulation in aerial parts and allocated more nitrogen in grains in a field experiment.	Nitrogen	166-174	NAC domain-containing protein 2	Triticum aestivum	27-33
26506375-9	2015	In addition, MSP treatment increased the levels of glucose (Glu) and muscle glycogen, whereas it decreased the accumulations of blood urea nitrogen (BUN) and lactic acid (Lac).	Nitrogen	139-147	macrophage stimulating 1 (hepatocyte growth factor-like)	Mus musculus	13-16
26469516-3	2015	Previously we showed that HA-hMC4R co-expression with hMRAPalpha, but not hMRAP2, specifically alters HA-hMC4R complex N-linked glycosylation.	Nitrogen	119-120	melanocortin 4 receptor	Homo sapiens	29-34
26311172-1	2015	This report introduces N-methylpyrrolidone hydroperoxide (NMPOOH)/base as an excellent reagent system for hydroxy-directed syn selective epoxidation of electron-deficient olefins, characterized by high diastereoselectivity, short reaction times and remarkable chemoselectivity, especially in presence of oxidatively labile nitrogen or sulfur atoms.	Nitrogen	323-331	synemin	Homo sapiens	123-126
26171930-5	2015	Despite rather small genome sizes, the Deltaproteobacterium possessed enhanced polysaccharide fermentation pathways, whereas the Epsilonproteobacterium was a versatile nitrogen reactor possessing nar, nap and nif gene clusters.	Nitrogen	168-176	catenin beta like 1	Homo sapiens	201-204
26456786-9	2015	Using human CYPs, CYP1A2, CYP2C19, CYP2D6, and/or CYP3A4 were found to catalyze N-oxide formation and N-, O-demethylation and/or oxidation.	Nitrogen	80-81	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	26-33
26118699-8	2015	Like RAGE isolated from mammalian sources, the degree of occupancy of the N-glycosylation sites was full at Asn25 and partial at Asn81 which was also subjected to non-enzymatic deamidation.	Nitrogen	74-75	advanced glycosylation end-product specific receptor	Homo sapiens	5-9
26207422-0	2015	Functional Roles of N-Linked Glycosylation of Human Matrix Metalloproteinase 9.	Nitrogen	20-21	matrix metallopeptidase 9	Homo sapiens	52-78
26207422-2	2015	Human (h)MMP-9 has two well-defined N-glycosylation sites at residues N38 and N120; however, their role has remained mostly unexplored partly because expression of the N-glycosylation-deficient N38S has been difficult due to a recently discovered single nucleotide polymorphism-dependent miRNA-mediated inhibitory mechanism.	Nitrogen	36-37	matrix metallopeptidase 9	Homo sapiens	9-14
26207422-7	2015	As with other glycoproteins, N-glycosylation strongly regulates hMMP-9 secretion.	Nitrogen	29-30	matrix metallopeptidase 9	Homo sapiens	64-70
26256407-4	2015	We show that chemical identification of boron and nitrogen substitutional defects can be achieved in the STM channel due to the quantum interference effect, arising due to the specific electronic structure of nitrogen dopant sites.	Nitrogen	50-58	sulfotransferase family 1A member 3	Homo sapiens	105-108
26256407-4	2015	We show that chemical identification of boron and nitrogen substitutional defects can be achieved in the STM channel due to the quantum interference effect, arising due to the specific electronic structure of nitrogen dopant sites.	Nitrogen	209-217	sulfotransferase family 1A member 3	Homo sapiens	105-108
26332921-8	2015	Concomitant with the reduction in nN   pi* delocalization energy, the sp(2) hybrid orbital of the carbonyl carbon becomes richer in p-character, suggesting the syn configuration causes the carbonyl carbon hybrid orbitals to adopt a geometry reminiscent of a tetrahedral-like intermediate.	Nitrogen	34-36	synemin	Homo sapiens	160-163
26379128-0	2015	Viral Restriction Activity of Feline BST2 Is Independent of Its N-Glycosylation and Induction of NF-kappaB Activation.	Nitrogen	64-65	bone marrow stromal cell antigen 2	Homo sapiens	37-41
26379128-9	2015	The shorter N-terminal cytoplasmic region of fBST2 compared with human BST2 did not apparently affect its anti-viral activity, which is independent of its N-glycosylation and ability to activate NF-kappaB.	Nitrogen	12-13	bone marrow stromal cell antigen 2	Homo sapiens	46-50
26206179-12	2015	We performed an N-glycomic analysis of human serum SP-D and the results show that a core-fucose is present in its N-glycan.	Nitrogen	16-17	surfactant protein D	Homo sapiens	51-55
26206179-13	2015	We also found that the N-glycosylation in serum SP-D was indeed altered in COPD, that is, fucosylation levels including core-fucosylation are significantly increased in COPD patients compared with non-COPD smokers.	Nitrogen	23-24	surfactant protein D	Homo sapiens	48-52
26008578-9	2015	These findings identify Coq9 as a multi-functional protein that is required for the function of Coq6 and Coq7 hydroxylases, for removal of the nitrogen substituent from pABA-derived Q intermediates, and is an essential component of the CoQ synthome.	Nitrogen	143-151	putative monooxygenase CAT5	Saccharomyces cerevisiae S288C	105-109
26093036-0	2015	A novel phosphorylation site of N-methyl-D-aspartate receptor GluN2B at S1284 is regulated by Cdk5 in neuronal ischemia.	Nitrogen	32-33	cyclin-dependent kinase 5	Mus musculus	94-98
26150355-3	2015	Through a complementation assay, we determined that LMAN1, a well-studied lectin-carrier protein, interacts with a secretion-competent N-glycosylated MMP-9 in the ER while N-glycosylation-deficient secretion-compromised MMP-9 does not.	Nitrogen	55-56	matrix metallopeptidase 9	Homo sapiens	150-155
26150355-3	2015	Through a complementation assay, we determined that LMAN1, a well-studied lectin-carrier protein, interacts with a secretion-competent N-glycosylated MMP-9 in the ER while N-glycosylation-deficient secretion-compromised MMP-9 does not.	Nitrogen	55-56	matrix metallopeptidase 9	Homo sapiens	220-225
26011743-5	2015	As crop diversity increased from one to five species, distinct soil microbial communities were related to increases in soil aggregation, organic carbon, total nitrogen, microbial activity and decreases in the carbon-to-nitrogen acquiring enzyme activity ratio.	Nitrogen	159-167	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	3-7
26011743-5	2015	As crop diversity increased from one to five species, distinct soil microbial communities were related to increases in soil aggregation, organic carbon, total nitrogen, microbial activity and decreases in the carbon-to-nitrogen acquiring enzyme activity ratio.	Nitrogen	219-227	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	3-7
26123121-0	2015	Fabrication of SnO2-SnO nanocomposites with p-n heterojunctions for the low-temperature sensing of NO2 gas.	Nitrogen	10-11	strawberry notch homolog 2	Homo sapiens	15-18
26148216-2	2015	Furthermore, an appropriate number of oxygen vacancies were introduced into the oxide during annealing at 400  C in ambient N2, making both SnO and SnO2 favorable for current conduction.	Nitrogen	124-126	strawberry notch homolog 2	Homo sapiens	140-143
25593096-1	2015	Optimization of the sulfonamide-based kappa opioid receptor (KOR) antagonist probe molecule ML140 through constraint of the sulfonamide nitrogen within a tetrahydroisoquinoline moiety afforded a marked increase in potency.	Nitrogen	136-144	opioid receptor kappa 1	Homo sapiens	38-59
25593096-1	2015	Optimization of the sulfonamide-based kappa opioid receptor (KOR) antagonist probe molecule ML140 through constraint of the sulfonamide nitrogen within a tetrahydroisoquinoline moiety afforded a marked increase in potency.	Nitrogen	136-144	opioid receptor kappa 1	Homo sapiens	61-64
25862406-0	2015	N-linked glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane.	Nitrogen	0-1	solute carrier family 1 member 5	Homo sapiens	32-38
25862406-0	2015	N-linked glycosylation of human SLC1A5 (ASCT2) transporter is critical for trafficking to membrane.	Nitrogen	0-1	solute carrier family 1 member 5	Homo sapiens	40-45
25862406-1	2015	The human amino acid transporter SLC1A5 (ASCT2) contains two N-glycosylation sites (N163 and N212) located in the large extracellular loop.	Nitrogen	61-62	solute carrier family 1 member 5	Homo sapiens	33-39
25862406-1	2015	The human amino acid transporter SLC1A5 (ASCT2) contains two N-glycosylation sites (N163 and N212) located in the large extracellular loop.	Nitrogen	61-62	solute carrier family 1 member 5	Homo sapiens	41-46
25782368-0	2015	A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors.	Nitrogen	21-22	dihydropyrimidinase-like 2	Rattus norvegicus	37-42
26666012-3	2015	Several studies indicated that variability in the expression of FMO3 involved in some nitrogen, or sulfur-containing durg metabolism.	Nitrogen	86-94	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	64-68
25855079-0	2015	N-glycosylation is essential for ileal ASBT function and protection against proteases.	Nitrogen	0-1	solute carrier family 10 member 2	Homo sapiens	39-43
25855079-4	2015	However, the exact roles of N-glycosylation of ASBT, and how it affects its function, is not known.	Nitrogen	28-29	solute carrier family 10 member 2	Homo sapiens	47-51
25855079-9	2015	Studies with the glycosylation deficient ASBT mutant (N10Q) showed that the N-glycosylation is not essential for ASBT targeting to plasma membrane.	Nitrogen	54-55	solute carrier family 10 member 2	Homo sapiens	41-45
25855079-12	2015	These results unravel novel roles for N-glycosylation of ASBT and suggest that high levels of glucose alter the composition of the glycan and may contribute to the increase in ASBT function in diabetes mellitus.	Nitrogen	38-39	solute carrier family 10 member 2	Homo sapiens	57-61
26125849-7	2015	The enzyme"s optimum temperature for catalytic activity at pH 6.0 is 70 C; importantly, more than 95% of the enzyme"s initial activity remained after a 2-h incubation at 60 C. The biochemical characterization of ENG1 confirmed the correct expression of the protein and showed that ENG1 expressed by the pHO-GAPDH-eng1-KanMX4-HO vector, in addition to its N-linked sites, is overglycosylated at its O-glycosylation sites compared with ENG1 expressed by the YEGAp/eng1 vector.	Nitrogen	213-214	endo-1,3(4)-beta-glucanase	Saccharomyces cerevisiae S288C	281-285
26125849-7	2015	The enzyme"s optimum temperature for catalytic activity at pH 6.0 is 70 C; importantly, more than 95% of the enzyme"s initial activity remained after a 2-h incubation at 60 C. The biochemical characterization of ENG1 confirmed the correct expression of the protein and showed that ENG1 expressed by the pHO-GAPDH-eng1-KanMX4-HO vector, in addition to its N-linked sites, is overglycosylated at its O-glycosylation sites compared with ENG1 expressed by the YEGAp/eng1 vector.	Nitrogen	213-214	endo-1,3(4)-beta-glucanase	Saccharomyces cerevisiae S288C	313-317
26125849-7	2015	The enzyme"s optimum temperature for catalytic activity at pH 6.0 is 70 C; importantly, more than 95% of the enzyme"s initial activity remained after a 2-h incubation at 60 C. The biochemical characterization of ENG1 confirmed the correct expression of the protein and showed that ENG1 expressed by the pHO-GAPDH-eng1-KanMX4-HO vector, in addition to its N-linked sites, is overglycosylated at its O-glycosylation sites compared with ENG1 expressed by the YEGAp/eng1 vector.	Nitrogen	213-214	endo-1,3(4)-beta-glucanase	Saccharomyces cerevisiae S288C	281-285
26125849-7	2015	The enzyme"s optimum temperature for catalytic activity at pH 6.0 is 70 C; importantly, more than 95% of the enzyme"s initial activity remained after a 2-h incubation at 60 C. The biochemical characterization of ENG1 confirmed the correct expression of the protein and showed that ENG1 expressed by the pHO-GAPDH-eng1-KanMX4-HO vector, in addition to its N-linked sites, is overglycosylated at its O-glycosylation sites compared with ENG1 expressed by the YEGAp/eng1 vector.	Nitrogen	213-214	endo-1,3(4)-beta-glucanase	Saccharomyces cerevisiae S288C	462-466
25066733-1	2015	BACKGROUND &amp; AIMS: Although the physiological effects of n-3 polyunsaturated fatty acids (n-3PUFA) are generally thought to require several weeks of exposure to allow their incorporation into plasma membranes, intravenous (IV) n-3PUFA attenuate the cardiovascular and neuroendocrine response to stress within 3 h. Whether oral n-3 PUFA exert similar early effects remains unknown.	Nitrogen	61-62	pumilio RNA binding family member 3	Homo sapiens	97-101
25066733-1	2015	BACKGROUND &amp; AIMS: Although the physiological effects of n-3 polyunsaturated fatty acids (n-3PUFA) are generally thought to require several weeks of exposure to allow their incorporation into plasma membranes, intravenous (IV) n-3PUFA attenuate the cardiovascular and neuroendocrine response to stress within 3 h. Whether oral n-3 PUFA exert similar early effects remains unknown.	Nitrogen	61-62	pumilio RNA binding family member 3	Homo sapiens	234-238
25382626-0	2015	The plasma membrane H(+) -ATPase AHA2 contributes to the root architecture in response to different nitrogen supply.	Nitrogen	100-108	H[+]-ATPase 2	Arabidopsis thaliana	33-37
25382626-7	2015	Our data demonstrate that primary and lateral root length were shorter and lower in aha2 mutant lines compared with wild-type plants in response to a variable nitrogen source.	Nitrogen	159-167	H[+]-ATPase 2	Arabidopsis thaliana	84-88
25382626-8	2015	This suggests that the PM proton pump AHA2 (Arabidopsis plasma membrane H(+) -ATPase isoform 2) is important for root growth and development during different nitrogen regimes.	Nitrogen	158-166	H[+]-ATPase 2	Arabidopsis thaliana	38-42
25839652-3	2015	In this study, we analyzed APR3 with bioinformatic tools and found that APR3 contains a potential signal peptide, a transmembrane region and 3 N-glycosylation sites, all of which are characteristics of lysosomal proteins.	Nitrogen	143-144	all-trans retinoic acid induced differentiation factor	Homo sapiens	72-76
25943704-0	2015	Direct electrochemistry of glucose oxidase on novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers composite film.	Nitrogen	66-74	hydroxyacid oxidase 1	Homo sapiens	27-42
25943704-1	2015	We have proposed a novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers (NCNSs@CNFs) composite film with high processability for the investigation of the direct electron transfer (DET) of glucose oxidase (GOx) and the DET-based glucose biosensing.	Nitrogen	39-47	hydroxyacid oxidase 1	Homo sapiens	207-222
25943704-1	2015	We have proposed a novel free-standing nitrogen-doped carbon nanospheres@carbon nanofibers (NCNSs@CNFs) composite film with high processability for the investigation of the direct electron transfer (DET) of glucose oxidase (GOx) and the DET-based glucose biosensing.	Nitrogen	39-47	hydroxyacid oxidase 1	Homo sapiens	224-227
25814217-9	2015	RESULTS: CNP reduced histological renal tubular damage and apoptosis induced by cisplatin and suppressed plasma blood urea nitrogen and creatinine levels, which were elevated by cisplatin administration.	Nitrogen	123-131	natriuretic peptide type C	Mus musculus	9-12
25164156-7	2015	In general, a significantly decreased expression of CD54, CD80, and HLA-DR membrane antigens was observed after 24 h of treatment with each nitrogen-containing bisphosphonate (p &lt; 0.05), but there was no significant difference in phagocytic activity versus controls.	Nitrogen	140-148	intercellular adhesion molecule 1	Homo sapiens	52-56
25761416-9	2015	A significant negative correlation between N-acetyl metabolite and ACAN gene expression levels was observed; this provides further evidence of N-acetyl as a biomarker of cartilage degeneration.	Nitrogen	43-44	aggrecan	Homo sapiens	67-71
25898205-0	2015	The influence of artificially introduced N-glycosylation sites on the in vitro activity of Xenopus laevis erythropoietin.	Nitrogen	41-42	erythropoietin S homeolog	Xenopus laevis	106-120
25898205-2	2015	Intriguingly, we have previously found that EPO in Xenopus laevis (xlEPO) has no N-glycosylation sites, and cross-reacts with the human EPO (huEPO) receptor despite low homology with huEPO.	Nitrogen	81-82	erythropoietin S homeolog	Xenopus laevis	44-47
25898205-9	2015	Hence, the EPO-EPOR binding site in X. laevis locates the distal region of artificially introduced three N-glycosylation sites, demonstrating that the vital conformation to exert biological activity is conserved between humans and X. laevis, despite the low similarity in primary structures of EPO and EPOR.	Nitrogen	105-106	erythropoietin receptor L homeolog	Xenopus laevis	15-19
25898205-9	2015	Hence, the EPO-EPOR binding site in X. laevis locates the distal region of artificially introduced three N-glycosylation sites, demonstrating that the vital conformation to exert biological activity is conserved between humans and X. laevis, despite the low similarity in primary structures of EPO and EPOR.	Nitrogen	105-106	erythropoietin S homeolog	Xenopus laevis	15-18
25245581-7	2015	Our results show that the CYP2D6 genotype influences the O-demethylation whereas CYP2C19 influences the N-demethylation of VEN and its metabolites.	Nitrogen	104-105	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	81-88
25689493-7	2015	Finally, we demonstrated that N-myristoylated Cblin prevented the wet weight loss, IRS-1 degradation, and MAFbx/atrogin-1 and MuRF-1 expression in gastrocnemius muscle of DEX-treated mice approximately fourfold more effectively than Cblin.	Nitrogen	30-31	tripartite motif-containing 63	Mus musculus	126-132
25437644-3	2015	In UUO rats, CNP administration induced a significant increase in plasma CNP levels, and caused a significant decrease in blood urea nitrogen and creatinine levels.	Nitrogen	133-141	natriuretic peptide C	Rattus norvegicus	13-16
25588735-8	2015	Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant.	Nitrogen	196-204	phosphoenolpyruvate carboxylase 1	Arabidopsis thaliana	122-126
25588735-8	2015	Interestingly, starch and sucrose accumulation could be prevented and nitrate levels could be maintained by supplying the ppc1/ppc2 mutant with exogenous malate and glutamate, suggesting that low nitrogen status resulted in the alteration of carbon metabolism and prompted the accumulation of starch and sucrose in the ppc1/ppc2 mutant.	Nitrogen	196-204	phosphoenolpyruvate carboxylase 1	Arabidopsis thaliana	319-323
25659750-2	2015	In earlier studies, GL3, in contrast to EGL3, was shown to be essential for accumulation of anthocyanins in response to nitrogen depletion.	Nitrogen	120-128	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	20-23
25889839-8	2015	Gain- and loss-of-function studies indicated that secretory ITLN1 facilitated the NDRG2 expression, resulting in down-regulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 9 (MMP-9), in NB cell lines SH-SY5Y, SK-N-BE(2), and SK-N-SH.	Nitrogen	63-64	matrix metallopeptidase 9	Homo sapiens	178-204
25889839-8	2015	Gain- and loss-of-function studies indicated that secretory ITLN1 facilitated the NDRG2 expression, resulting in down-regulation of vascular endothelial growth factor (VEGF) and matrix metalloproteinase 9 (MMP-9), in NB cell lines SH-SY5Y, SK-N-BE(2), and SK-N-SH.	Nitrogen	63-64	matrix metallopeptidase 9	Homo sapiens	206-211
25533401-3	2015	Molecular modeling studies predicted that the improved inhibitory activity is induced by additional hydrogen bonds between the nitrogen atom of the pyrrolidine ring and Arg48 and by an interaction between the dimethylamino-substituent of the pyrrolidine moiety and a relatively hydrophobic groove in the RAGE binding site.	Nitrogen	127-135	advanced glycosylation end-product specific receptor	Homo sapiens	304-308
25513968-5	2015	N-Fluoroalkylation was preferable to O-alkylation to keep a selective KOR binding.	Nitrogen	0-1	opioid receptor kappa 1	Homo sapiens	70-73
25513968-6	2015	Compared to JDTic, the N-fluoropropyl derivative 2 bound to KOR with an only 4-fold lower affinity and a higher selectivity relative to MOR and DOR [Ki(kappa) = 1.6 nM; Ki(mu)/Ki(kappa) = 12; Ki(delta)/Ki(kappa) = 159 for 2versus Ki(kappa) = 0.42 nM; Ki(mu)/Ki(kappa) = 9; Ki(delta)/Ki(kappa) = 85 for JDTic].	Nitrogen	23-24	opioid receptor kappa 1	Homo sapiens	60-63
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	Nitrogen	81-82	heat shock protein family A (Hsp70) member 8	Homo sapiens	58-63
25349282-9	2015	We further traced QTLs down to single-nucleotide resolution and uncovered loss-of-function mutations in RIM15, PUT4, DAL1, and DAL4 as the genetic basis for nitrogen source use variations.	Nitrogen	157-165	allantoin permease	Saccharomyces cerevisiae S288C	127-131
25480007-0	2015	Response of nitrate reductase activity and NIA genes expression in roots of Arabidopsis hxk1 mutant treated with selected carbon and nitrogen metabolites.	Nitrogen	133-141	hexokinase 1	Arabidopsis thaliana	88-92
26360751-7	2015	The rMBR permeate contained an average of 1.7 mg/L total nitrogen (TN) with less than 1 mg/L NO(3)-N, while the TN concentration in the MBR permeate averaged 5 mg/L with 3.5 mg/L NO(3)-N.	Nitrogen	57-65	translocator protein	Rattus norvegicus	4-8
25517874-0	2014	Activation of RidA chaperone function by N-chlorination.	Nitrogen	41-42	reactive intermediate imine deaminase A homolog	Homo sapiens	14-18
25517874-5	2014	N-chlorination increases hydrophobicity of RidA and promotes binding to a wide spectrum of unfolded cytosolic proteins.	Nitrogen	0-1	reactive intermediate imine deaminase A homolog	Homo sapiens	43-47
25517874-7	2014	HOCl-mediated N-chlorination thus is a cysteine-independent post-translational modification that reversibly turns RidA into an effective chaperone holdase, which plays a crucial role in the protection of cytosolic proteins during oxidative stress.	Nitrogen	14-15	reactive intermediate imine deaminase A homolog	Homo sapiens	114-118
25187293-3	2014	Plant-specific N-glycosylation patterns elaborated within the Golgi complex are a major limitation of using plants to produce biopharmaceuticals as the presence of beta1,2 xylose and/or alpha1,3 fucose residues on the recombinant glycoprotein can render the product immunogenic if administrated parenterally.	Nitrogen	15-16	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	164-171
25347750-0	2014	Synthesis of syn-1,3-aminoalcohols via a Ru-catalyzed N-demethylative rearrangement of isoxazolidines and its application in a three-step total synthesis of HPA-12.	Nitrogen	54-55	synapsin I	Homo sapiens	13-18
25299197-10	2014	Univariate regression analysis showed that the percent changes in serum RBP4 concentration before and after kidney transplantation were positively correlated with serum creatinine, blood urea nitrogen, phosphate, and pre-albumin concentrations and negatively correlated with the estimated glomerular filtration rate.	Nitrogen	192-200	retinol binding protein 4	Homo sapiens	72-76
25131748-6	2014	A phylogenetic analysis of ORF5 revealed that this mutant and five other strains, belong to an intermediate subgenotype (inter-subgenotype), which is characterized by extensive mutations, especially in the signal peptide and N-glycosylation sites.	Nitrogen	225-226	CWC15 spliceosome associated protein homolog	Homo sapiens	27-31
24952318-1	2014	Bean plants from the Phaseolus genus are widely consumed and represent a nitrogen source for human nutrition.	Nitrogen	73-81	brain expressed associated with NEDD4 1	Homo sapiens	0-4
24786828-2	2014	In yeast, the Nitrogen permease regulators 2 and 3 (Npr2 and Npr3) mediate an essential response to amino-acid limitation upstream of TORC1.	Nitrogen	14-22	nitrogen permease regulating protein NPR2	Saccharomyces cerevisiae S288C	52-56
24548141-3	2014	NIT2 expression is down-regulated in ammonium and up-regulated under nitrogen deprivation.	Nitrogen	69-77	uncharacterized protein	Chlamydomonas reinhardtii	0-4
25135935-0	2014	Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.	Nitrogen	41-42	thioredoxin reductase 1	Homo sapiens	0-14
24293102-7	2014	15-LOX and VDR are key neuromolecular factors essential in lipid-mediated signaling, neurotrophic support, defense against reactive oxygen and nitrogen species (reactive oxygen and nitrogen species), and neuroprotection in the CNS.	Nitrogen	143-151	vitamin D receptor	Homo sapiens	11-14
24293102-7	2014	15-LOX and VDR are key neuromolecular factors essential in lipid-mediated signaling, neurotrophic support, defense against reactive oxygen and nitrogen species (reactive oxygen and nitrogen species), and neuroprotection in the CNS.	Nitrogen	181-189	vitamin D receptor	Homo sapiens	11-14
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	argininosuccinate lyase	Homo sapiens	178-201
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	N-acetylglutamate synthase	Homo sapiens	213-240
25039902-2	2014	Decreased excretion of nitrogen in the urea cycle due to deficiency of carbamoyl phosphate synthase I (CPSI), ornithine transcarbamylase (OTC), argininosuccinate synthase (ASS), argininosuccinate lyase (ASL), and N-acetyl glutamate synthase (NAGS) causes hyperammonemia.	Nitrogen	23-31	N-acetylglutamate synthase	Homo sapiens	242-246
25017168-0	2014	Challenges to develop nitrogen-fixing cereals by direct nif-gene transfer.	Nitrogen	22-30	S100 calcium binding protein A9	Homo sapiens	56-59
24567494-0	2014	Sixteen cytosolic glutamine synthetase genes identified in the Brassica napus L. genome are differentially regulated depending on nitrogen regimes and leaf senescence.	Nitrogen	130-138	glutamine synthetase, chloroplastic	Brassica napus	18-38
24760879-1	2014	Vitrification involves the use of cryoprotectants (CPAs) and liquid nitrogen (LN2), which may cause osmotic damage and cryoinjury to oocytes.	Nitrogen	68-76	NZ lupus nephritis 2	Mus musculus	78-81
24949957-7	2014	In rhabdomyosarcomas, CD97 was strongly upregulated and in part more N-glycosylated compared to normal skeletal muscle.	Nitrogen	69-70	adhesion G protein-coupled receptor E5	Mus musculus	22-26
24828975-8	2014	The N-demethylation was catalyzed by CYP2B6, CYP2C19, CYP2D6, and CYP3A4, the aromatic hydroxylation by CYP2C19 and CYP2D6, and the aliphatic hydroxylation was catalyzed by CYP1A2, CYP2B6, CYP2C19, and CYP3A4.	Nitrogen	4-5	cytochrome P450, family 2, subfamily d, polypeptide 4	Rattus norvegicus	54-60
24759841-5	2014	Each patient harbors 2 novel heteroallelic mutations in DPAGT1, an enzyme subserving protein N-glycosylation.	Nitrogen	93-94	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	56-62
24362079-3	2014	The obtained results demonstrate that nitrogen doping in ZnO matrix offers a striking electrocatalytic activity to the immobilized uricase towards the oxidation of analyte (uric acid) and promotes the direct transfer of electrons from active sites of enzyme onto the electrode without any mediator.	Nitrogen	38-46	urate oxidase (pseudogene)	Homo sapiens	131-138
24658171-5	2014	Here, we report spatially resolved magnetic resonance studies of electron spin ensembles confined to a "spin nanowire" formed by nitrogen ion implantation in diamond.	Nitrogen	129-137	spindlin 1	Homo sapiens	74-78
24658171-5	2014	Here, we report spatially resolved magnetic resonance studies of electron spin ensembles confined to a "spin nanowire" formed by nitrogen ion implantation in diamond.	Nitrogen	129-137	spindlin 1	Homo sapiens	104-108
24699741-1	2014	Nitrogen-containing bisphosphonates (N-BPs), such as risedronate and zoledronate, are currently used as a clinical drug for bone-resorption diseases and are potent inhibitors of farnesyl pyrophosphate synthase (FPPS).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	178-209
24699741-1	2014	Nitrogen-containing bisphosphonates (N-BPs), such as risedronate and zoledronate, are currently used as a clinical drug for bone-resorption diseases and are potent inhibitors of farnesyl pyrophosphate synthase (FPPS).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	211-215
24616224-2	2014	A selective autophagic pathway for 60S ribosomal subunits elicited by nitrogen starvation in yeast-ribophagy-was recently described and requires the Ubp3-Bre5 deubiquitylating enzyme.	Nitrogen	70-78	mRNA-binding ubiquitin-specific protease UBP3	Saccharomyces cerevisiae S288C	149-153
24572366-1	2014	The NRT1/PTR family of proton-coupled transporters are responsible for nitrogen assimilation in eukaryotes and bacteria through the uptake of peptides.	Nitrogen	71-79	nitrate transporter 1.1	Arabidopsis thaliana	4-8
24403586-14	2014	The Env folding process involves extensive cross-linking of 10 Cys residues by disulfide bond formation and heavy N-glycosylation on ~30 Asn residues.	Nitrogen	114-115	endogenous retrovirus group K member 20	Homo sapiens	4-7
24336836-3	2014	Next, the intermediate loses N2 to form the singlet TMM diyl M3S, which can then undergo another concerted (3 + 2) cycloaddition to generate the linearly-fused cis-trans or cis-syn triquinane products.	Nitrogen	29-31	synemin	Homo sapiens	177-180
24490900-0	2014	Nitrogen-containing bisphosphonates inhibit RANKL- and M-CSF-induced osteoclast formation through the inhibition of ERK1/2 and Akt activation.	Nitrogen	0-8	colony stimulating factor 1 (macrophage)	Mus musculus	55-60
24051299-11	2014	Raman spectroscopy, (31)P NMR and DFT calculations (DFT:B3LYP/6-311++G(**)) indicated that the donor atoms are oxygen in the phosphate group, the nitrogen of the guanidine group and the oxygen of the carboxylate group.	Nitrogen	146-154	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	58-61
24516460-0	2013	Use of Plackett-Burman design for rapid screening of nitrogen and carbon sources for the production of lipase in solid state fermentation by Yarrowia lipolytica from mustard oil cake (Brassica napus).	Nitrogen	53-61	lipase-like	Brassica napus	103-109
24012777-7	2014	The fat-1 transgenic mouse model is capable of converting n-6 to n-3 fatty acids leading to an increase in n-3 fatty acid content with a balanced n-6/n-3 fatty acid ratio in all tissues.	Nitrogen	13-14	FAT atypical cadherin 1	Mus musculus	4-9
24012777-7	2014	The fat-1 transgenic mouse model is capable of converting n-6 to n-3 fatty acids leading to an increase in n-3 fatty acid content with a balanced n-6/n-3 fatty acid ratio in all tissues.	Nitrogen	17-18	FAT atypical cadherin 1	Mus musculus	4-9
25180193-0	2014	Invasive potential of melanoma cells correlates with the expression of MT1-MMP and regulated by modulating its association with motility receptors via N-glycosylation on the receptors.	Nitrogen	151-152	matrix metallopeptidase 14 (membrane-inserted)	Mus musculus	71-78
25276837-7	2014	In Rspo3, four N-glycosylation sites were noted.	Nitrogen	15-16	R-spondin 3	Homo sapiens	3-8
25032222-9	2014	Taken together, silibinin inhibits ICAM-1 expression and its function through altered O-linked glycosylation in NF-kappaB and STAT1 signaling pathways and decreases the N-linked glycosylation of ICAM-1 transmembrane protein in proinflammatory cytokine-stimulated ARPE-19 cells.	Nitrogen	112-113	intercellular adhesion molecule 1	Homo sapiens	35-41
24200968-8	2014	miR-888 also increased colony formation in PC3-N and LNCaP cells, supporting an oncogenic role for this miRNA in the prostate.	Nitrogen	47-48	microRNA 888	Homo sapiens	0-7
24172032-2	2014	BPs with nitrogen-containing side chains (N-BPs) are known to act as inhibitors for farnesyl pyrophosphate synthase (FPPS), a key enzyme in the mevalonate pathway.	Nitrogen	9-17	farnesyl diphosphate synthase	Homo sapiens	84-115
24172032-2	2014	BPs with nitrogen-containing side chains (N-BPs) are known to act as inhibitors for farnesyl pyrophosphate synthase (FPPS), a key enzyme in the mevalonate pathway.	Nitrogen	9-17	farnesyl diphosphate synthase	Homo sapiens	117-121
31773048-8	2014	We found that N- and C-terminal fragments, encoding multiple motifs including sequences involved in binding integrins and CD44, a domain know to promote adhesion contribute to OPN"s ability to increase HIV replication.	Nitrogen	14-15	CD44 molecule (Indian blood group)	Homo sapiens	122-126
24323398-3	2014	After 48 h of culture under nitrogen with a resulting medium pH of 7.8, sorted hypoxic PC3 cells yielded a higher percentage and concentration/10(5) of cells in a doubly labeled (DL) CD44(+)/CD41(+) side fraction compared with control cells cultured under normoxia (5 % CO2 in the ambient atmosphere at 37  C).	Nitrogen	28-36	CD44 antigen	Mus musculus	183-187
24415948-3	2014	We find that rapid adaptive evolution in nitrogen-poor environments is dominated by the de novo generation and selection of copy number variants (CNVs), a large fraction of which contain genes encoding specific nitrogen transporters including PUT4, DUR3 and DAL4.	Nitrogen	41-49	allantoin permease	Saccharomyces cerevisiae S288C	258-262
24108359-1	2013	The trisubstituted enolate- and C-C bond-forming capacities of engineered carboxymethylproline synthases CMPSs are coupled with the malonyl-CoA synthetase MatB to enable stereoselective preparation of 5- and 6-membered N-heterocycles functionalised with alkyl-substituted carboxymethyl side chains, starting from achiral alkyl-substituted malonic acids and L-amino acid semialdehydes.	Nitrogen	219-220	acyl-CoA synthetase family member 3	Homo sapiens	132-154
24390366-8	2013	Multiple regression analysis revealed that LECT2 is independently related to gamma-glutamyl transpeptidase (gamma-GTP), triglyceride, and age in males, whereas in females it was related to the homeostasis model assessment ratio, blood urea nitrogen, high-density lipoprotein cholesterol, and gamma-GTP.	Nitrogen	240-248	leukocyte cell derived chemotaxin 2	Homo sapiens	43-48
24119763-3	2013	The pathological lesions that define AD would be linked to the insidious accumulation of nitrogen, having invaded the brain interstitial fluid (ISF) from the blood via the physiological cycling pool of vascular glucose transporters (GLUT-1).	Nitrogen	89-97	solute carrier family 2 member 1	Homo sapiens	233-239
24567903-4	2014	Microarray analysis uncovered transcriptional changes in nitrogen metabolism, including CG9510, homolog of human argininosuccinate lyase (ASL).	Nitrogen	57-65	argininosuccinate lyase	Homo sapiens	113-136
24567903-4	2014	Microarray analysis uncovered transcriptional changes in nitrogen metabolism, including CG9510, homolog of human argininosuccinate lyase (ASL).	Nitrogen	57-65	argininosuccinate lyase	Homo sapiens	138-141
24567903-7	2014	Metabolomic analysis of CG9510 knockdown flies confirmed functional similarity to ASL, regulating the balance of carbon and nitrogen metabolism.	Nitrogen	124-132	argininosuccinate lyase	Homo sapiens	82-85
24028499-4	2013	B3LYP/6-311+G(d,p) density functional theory (DFT) calculations show that by using a strategy of resonance donation from six nitrogen atoms via three substituted imidazole subunits, more than 4-fold increase in cation-pi interaction energy (E(M)(+)) can be achieved for a single phenyl ring compared to benzene.	Nitrogen	125-133	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	2-5
23928372-9	2013	Klotho deficiency in KL(+/-) mutant mice exacerbated STZ-induced increases in urine albumin, blood urea nitrogen, expansion of mesangial matrix in renal glomeruli, and kidney hypertrophy, suggesting a protective role of klotho in kidney function and structure.	Nitrogen	104-112	klotho	Mus musculus	0-6
23893374-5	2013	In contrast, there is significant overlap for the signals for C-7 and the more interior carbons in a solution of n-C16 or longer chain alkanes in CDCl3 .	Nitrogen	1-2	complement C7	Homo sapiens	62-65
23988446-7	2013	Expression of EpCAM and ERAP2 in vitro in the presence of dog pancreas rough microsomes (ER vesicles) confirmed N-linked glycosylation, processing in ER and the size of EpCAM.	Nitrogen	112-113	epithelial cell adhesion molecule	Canis lupus familiaris	14-19
23988446-7	2013	Expression of EpCAM and ERAP2 in vitro in the presence of dog pancreas rough microsomes (ER vesicles) confirmed N-linked glycosylation, processing in ER and the size of EpCAM.	Nitrogen	112-113	ERAP2	Canis lupus familiaris	24-29
24058541-0	2013	The role of N-glycosylation in folding, trafficking, and functionality of lysosomal protein CLN5.	Nitrogen	12-13	CLN5 intracellular trafficking protein	Homo sapiens	92-96
24058541-5	2013	Additionally, localization studies showed that the lack of N-glycosylation on certain sites (N179, N252, N304, or N320) caused CLN5 retention in the endoplasmic reticulum, indicating that glycosylation is important for protein folding.	Nitrogen	59-60	CLN5 intracellular trafficking protein	Homo sapiens	127-131
24058541-9	2013	Our results suggest that there are functional differences in various N-glycosylation sites of CLN5 which affect folding, trafficking, and lysosomal function of CLN5.	Nitrogen	69-70	CLN5 intracellular trafficking protein	Homo sapiens	94-98
24058541-9	2013	Our results suggest that there are functional differences in various N-glycosylation sites of CLN5 which affect folding, trafficking, and lysosomal function of CLN5.	Nitrogen	69-70	CLN5 intracellular trafficking protein	Homo sapiens	160-164
21655928-6	2013	The levels of HTNV-specific CD8(+) T lymphocytes in PBMC of patients with HFRS were negatively correlated with the levels of blood urea nitrogen and creatinine in plasma.	Nitrogen	136-144	CD8a molecule	Homo sapiens	28-31
23770596-0	2013	Abscisic acid and aldehyde oxidase activity in maize ear leaf and grain relative to post-flowering photosynthetic capacity and grain-filling rate under different water/nitrogen treatments.	Nitrogen	168-176	indole-3-acetaldehyde oxidase	Zea mays	18-34
23991019-8	2013	Treatment with a beta1-integrin function-blocking antibody, AIIB2, preferentially decreased the N-glycosylated form of beta1-integrin, impaired mammosphere formation and restored epithelial phenotype in mesenchymal colony clusters.	Nitrogen	96-97	integrin subunit beta 1	Homo sapiens	119-133
23991019-10	2013	While the major determinant of trastuzumab resistance in mesenchymal colony clusters is likely the down regulation of the HER-2 protein, our evidence suggests that multiple factors may contribute, including expression of N-glycosylated beta1-integrin.	Nitrogen	221-222	integrin subunit beta 1	Homo sapiens	236-250
23947843-4	2013	The mean square displacement and intermediate scattering function can fit well the simulation data of the temperature-dependent translational dynamics of nitrogen atoms of elastin for a wide range of temperatures and various scattering vectors.	Nitrogen	154-162	elastin	Homo sapiens	172-179
23907884-2	2013	Consequently, the N-glycosylic bond exhibits a syn conformation, with a chi torsion angle of 61.6 (2) , and the pentofuranosyl residue adopts a C2"-endo envelope conformation (2E, S-type), with P = 162.1 (1)  and taum = 36.2 (1) .	Nitrogen	18-19	synemin	Homo sapiens	47-50
23701949-6	2013	Rather more, abundantly present Stx5 was capable of translocating ER-/N-glycosylated VLDL-R to the plasma membrane, and thus was insensitive to BFA treatment and low temperature.	Nitrogen	70-71	syntaxin 5	Homo sapiens	32-36
23794630-1	2013	The potent nitrogen-containing bisphosphonate zoledronate inhibits farnesyl pyrophosphate synthase, a key enzyme of the mevalonate pathway that is often hyperactive in malignant cells.	Nitrogen	11-19	farnesyl diphosphate synthase	Homo sapiens	67-98
23886338-7	2013	Moreover, lowering the dietary n-6: n-3 FAR led to an increase in the expression of the pre-synaptic protein synaptophysin in the CA1 hippocampal subregion of the rat brain.	Nitrogen	16-17	synaptophysin	Rattus norvegicus	109-122
23886338-8	2013	CONCLUSIONS: These findings support the notion that decreasing the dietary n-6: n-3 FAR will lead to an intensified hippocampal synaptophysin expression and increased neuron size and proliferation in the rat brain.	Nitrogen	21-22	synaptophysin	Rattus norvegicus	128-141
23567996-1	2013	Human flavin-containing monooxygenase 3 (FMO3, EC 1.14.13.8) in liver catalyzes a variety of oxygenations of nitrogen- and sulfur-containing medicines and xenobiotic substances.	Nitrogen	109-117	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	6-39
23567996-1	2013	Human flavin-containing monooxygenase 3 (FMO3, EC 1.14.13.8) in liver catalyzes a variety of oxygenations of nitrogen- and sulfur-containing medicines and xenobiotic substances.	Nitrogen	109-117	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	41-45
23703724-19	2013	These findings provide no evidence for harm and support possible benefits of n-3 PUFA consumption on insulin sensitivity and adipocyte function.	Nitrogen	8-9	pumilio RNA binding family member 3	Homo sapiens	81-85
24900728-1	2013	2alpha-Heteroarylethyl-1alpha,25-dihydroxyvitamin D3 analogues, which were designed to form a hydrogen bond between Arg274 of human vitamin D receptor (hVDR) and a nitrogen atom of the heteroaromatic ring at the 2alpha-position, were synthesized.	Nitrogen	164-172	vitamin D receptor	Homo sapiens	132-150
24900728-1	2013	2alpha-Heteroarylethyl-1alpha,25-dihydroxyvitamin D3 analogues, which were designed to form a hydrogen bond between Arg274 of human vitamin D receptor (hVDR) and a nitrogen atom of the heteroaromatic ring at the 2alpha-position, were synthesized.	Nitrogen	164-172	vitamin D receptor	Homo sapiens	152-156
23589073-2	2013	Despite its widespread distribution, the study of the naturally occurring isotope of nitrogen, (14)N (99.6%), has been relatively limited as it is a spin-1 nucleus that typically exhibits a large quadrupolar interaction.	Nitrogen	85-93	spindlin 1	Homo sapiens	149-155
23724116-8	2013	Hormone treatment increased the activity of Insulin like Growth Factor 1-Receptor (IGF-1R) ten-fold and this was associated with a concomitant increase in the N-linked glycosylation of the receptor, analyzed by lectin enrichment experiments.	Nitrogen	159-160	insulin like growth factor 1 receptor	Homo sapiens	44-81
23724116-10	2013	Inhibition of N-linked glycosylation resulted in accumulation of IGF-1R pro-receptor with altered mobility as shown by immunoprecipitation.	Nitrogen	14-15	insulin like growth factor 1 receptor	Homo sapiens	65-71
23704884-6	2013	RESULTS: At each time point, planktonic cells of WT strain cultured in yeast nitrogen base displayed a much higher expression of EAP1 and HWP1, and a moderately higher ALS3 expression, than HM cells.	Nitrogen	77-85	Eap1p	Saccharomyces cerevisiae S288C	129-133
23548572-2	2013	We previously reported that GnT-IVa glycosyltransferase is required for the production of an N-glycan structure that acts as a ligand for galectins to form the glycan-galectin lattice that maintains the stable cell surface expression of GLUT2, and cellular glucose transport activity, although the functional relevance of the N-glycosylation of GLUT2 to its membrane sub-domain distribution is not fully understood.	Nitrogen	93-94	solute carrier family 2 member 2	Homo sapiens	237-242
23548572-2	2013	We previously reported that GnT-IVa glycosyltransferase is required for the production of an N-glycan structure that acts as a ligand for galectins to form the glycan-galectin lattice that maintains the stable cell surface expression of GLUT2, and cellular glucose transport activity, although the functional relevance of the N-glycosylation of GLUT2 to its membrane sub-domain distribution is not fully understood.	Nitrogen	93-94	solute carrier family 2 member 2	Homo sapiens	345-350
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	77-85	allantoin permease	Saccharomyces cerevisiae S288C	28-32
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	148-156	allantoin permease	Saccharomyces cerevisiae S288C	28-32
23498202-7	2013	The expression of the genes DAL4, DAL5, DUR3 and GAP1 was clearly related to nitrogen depletion and thus, GAP1 and DAL4 were selected as markers of nitrogen deficiency.	Nitrogen	148-156	allantoin permease	Saccharomyces cerevisiae S288C	115-119
23439496-4	2013	Here, we first show in proof-of-concept studies that simple coinjection of a hepatocyte-targeted, N-acetylgalactosamine-conjugated melittin-like peptide (NAG-MLP) with a liver-tropic cholesterol-conjugated siRNA (chol-siRNA) targeting coagulation factor VII (F7) results in efficient F7 knockdown in mice and nonhuman primates without changes in clinical chemistry or induction of cytokines.	Nitrogen	98-99	cysteine and glycine-rich protein 3	Mus musculus	158-161
23456435-3	2013	During biosynthesis, CSQ2 undergoes N-linked glycosylation and phosphorylation by protein kinase CK2.	Nitrogen	36-37	calsequestrin 2	Canis lupus familiaris	21-25
23471971-0	2013	Increased activity of the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor TI-VAMP/VAMP7 by tyrosine phosphorylation in the Longin domain.	Nitrogen	44-45	vesicle associated membrane protein 7	Homo sapiens	106-113
23471971-0	2013	Increased activity of the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein receptor TI-VAMP/VAMP7 by tyrosine phosphorylation in the Longin domain.	Nitrogen	44-45	vesicle associated membrane protein 7	Homo sapiens	114-119
23343763-5	2013	A similar sluggish exit from quiescence is also observed on reprovision of nutrients to nitrogen-starved CTNNBL1-deficient yeast.	Nitrogen	88-96	catenin, beta like 1	Mus musculus	105-112
23291178-8	2013	We successfully synthesized milligram quantities of functional (15)N-labeled higher eukaryotic proteins, bovine pancreatic trypsin inhibitor (BPTI) and human lysozyme C (LYZ).	Nitrogen	67-68	spleen trypsin inhibitor I	Bos taurus	105-140
23291178-8	2013	We successfully synthesized milligram quantities of functional (15)N-labeled higher eukaryotic proteins, bovine pancreatic trypsin inhibitor (BPTI) and human lysozyme C (LYZ).	Nitrogen	67-68	spleen trypsin inhibitor I	Bos taurus	142-146
23250752-0	2013	N-glycosylation-dependent control of functional expression of background potassium channels K2P3.1 and K2P9.1.	Nitrogen	0-1	potassium two pore domain channel subfamily K member 9	Homo sapiens	103-109
23211429-2	2013	Rare mutations in FMO3 are responsible for defective N-oxidation of dietary trimethylamine leading to trimethylaminuria, and common genetic variation in FMO3 has been linked to interindividual variability in metabolic function that may be substrate specific.	Nitrogen	53-54	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	18-22
23178939-0	2013	Coordinate regulation of N-glycosylation gene DPAGT1, canonical Wnt signaling and E-cadherin adhesion.	Nitrogen	25-26	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	46-52
23178939-3	2013	N-glycosylation of E-cadherin is controlled by the DPAGT1 gene, a key regulator of the N-glycosylation pathway.	Nitrogen	0-1	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	51-57
23178939-3	2013	N-glycosylation of E-cadherin is controlled by the DPAGT1 gene, a key regulator of the N-glycosylation pathway.	Nitrogen	87-88	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	51-57
23178939-8	2013	Remarkably, a 2.4-fold increase in the DPAGT1 mRNA level resulted in increased N-glycosylation and reduced membrane localization of E-cadherin, coincident with dramatic changes in cell morphology.	Nitrogen	48-49	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	39-45
23476457-2	2013	Further, the N-H bond is syn to the ortho-nitro group in the sulfonyl benzene ring and also syn to both the ortho- and meta-Cl atoms in the aniline ring.	Nitrogen	13-14	synemin	Homo sapiens	25-28
23476457-2	2013	Further, the N-H bond is syn to the ortho-nitro group in the sulfonyl benzene ring and also syn to both the ortho- and meta-Cl atoms in the aniline ring.	Nitrogen	13-14	synemin	Homo sapiens	92-95
22820730-7	2013	Macrocycles with a basic nitrogen in the linker form a salt bridge with Asp86 in CDK2 and Asp698 in FLT3.	Nitrogen	25-33	cyclin-dependent kinase 2	Mus musculus	81-85
22820730-7	2013	Macrocycles with a basic nitrogen in the linker form a salt bridge with Asp86 in CDK2 and Asp698 in FLT3.	Nitrogen	25-33	FMS-like tyrosine kinase 3	Mus musculus	100-104
23925152-4	2013	The insertion of arginine at position 11 and the loss of the N-linked glycosylation site were indispensable for acquiring pure CXCR4-tropism, which were confirmed by cell-cell fusion assay and phenotype analysis of recombinant HIV-1 variants.	Nitrogen	61-62	C-X-C motif chemokine receptor 4	Homo sapiens	127-132
23409241-2	2013	Herein, we report a resonant tunneling system, quasi-2D Cu(2)O/SnO(2) p-n heterostructure multi-layer film, prepared by electrochemical deposition in a quasi-2D ultra-thin liquid layer.	Nitrogen	5-6	strawberry notch homolog 2	Homo sapiens	63-66
22552861-8	2012	These results suggest that the N-glycosylation moiety of GliPr1L1 is processed during the transit in the caput.	Nitrogen	31-32	GLIPR1 like 1	Bos taurus	57-65
23131049-1	2012	Previous research has demonstrated that 3-[5-(4-chlorophenyl)-2,3-dimethyl-3-isoxazolidinyl]pyridine (SYP-Z048), a newly developed nitrogen heterocycle substituted isoxazolidine compound, has good protective and curative activities against a wide range of fungal diseases of fruits and vegetables caused by Ascomycetes, Basidiomycetes, and Deuteromycetes.	Nitrogen	131-139	synaptophysin	Homo sapiens	102-105
23102207-4	2012	Introduction of an additional nitrogen atom inside the tricyclic framework led to an increase of both the affinity and selectivity for 5-HT(4)R, suggesting the design of the antagonist 4v, exhibiting a high affinity of 0.04 nM.	Nitrogen	30-38	5-hydroxytryptamine receptor 4	Homo sapiens	135-143
23047007-4	2012	We were able to determine the structural domains of BST-2 that are essential to restrict XMRV, including the transmembrane domain, the coiled-coil ectodomain, the C-terminal glycosylphosphatidylinositol (GPI) anchor, the two putative N-linked glycosylation sites, and the three extracellular cysteine residues.	Nitrogen	234-235	bone marrow stromal cell antigen 2	Homo sapiens	52-57
22989333-2	2012	Strategic incorporation of a nitrogen atom in the new constrained ring allowed us to develop SAR around the S2" binding pocket and ultimately resulted in analogues with low nanomolar potency for BACE1.	Nitrogen	29-37	beta-secretase 1	Rattus norvegicus	195-200
23037902-3	2012	Concerns about a high n-6 PUFA intake has been raised, because n-6 PUFA may weaken the effects of n-3 PUFA.	Nitrogen	2-3	pumilio RNA binding family member 3	Homo sapiens	26-30
23037902-3	2012	Concerns about a high n-6 PUFA intake has been raised, because n-6 PUFA may weaken the effects of n-3 PUFA.	Nitrogen	2-3	pumilio RNA binding family member 3	Homo sapiens	67-71
23037902-3	2012	Concerns about a high n-6 PUFA intake has been raised, because n-6 PUFA may weaken the effects of n-3 PUFA.	Nitrogen	2-3	pumilio RNA binding family member 3	Homo sapiens	67-71
23125802-2	2012	The N-H group attached to the exocyclic C=C bond is in a syn arrangement with respect to the C=O bond of the pyrazolone group and an intra-molecular N-H O hydrogen bond is observed.	Nitrogen	4-5	synemin	Homo sapiens	57-60
22739108-6	2012	Streptozotocin-induced diabetic manifestations were attenuated in sEH-deficient mice relative to wild-type controls, with significantly decreased levels of Hb A(1c), creatinine, and blood urea nitrogen and urinary microalbumin excretion.	Nitrogen	193-201	epoxide hydrolase 2, cytoplasmic	Mus musculus	66-69
22669605-0	2012	Regulation of anthocyanin biosynthesis by nitrogen in TTG1-GL3/TT8-PAP1-programmed red cells of Arabidopsis thaliana.	Nitrogen	42-50	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	54-58
22669605-0	2012	Regulation of anthocyanin biosynthesis by nitrogen in TTG1-GL3/TT8-PAP1-programmed red cells of Arabidopsis thaliana.	Nitrogen	42-50	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	59-62
22669605-2	2012	In this investigation, we report the nitrogen regulation of anthocyanin biosynthesis activated by TTG1-GL3/TT8-PAP1 in red pap1-D cells.	Nitrogen	37-45	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	98-102
22669605-2	2012	In this investigation, we report the nitrogen regulation of anthocyanin biosynthesis activated by TTG1-GL3/TT8-PAP1 in red pap1-D cells.	Nitrogen	37-45	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	103-106
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	24-32	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	195-199
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	24-32	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	200-203
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	116-124	Transducin/WD40 repeat-like superfamily protein	Arabidopsis thaliana	195-199
22669605-8	2012	These results show that nitrogen regulation of anthocyanin biosynthesis in red cells undergoes a mechanism by which nitrogen controls the expression of genes encoding both main components of the TTG1-GL3/TT8-PAP1 complex and negative regulators.	Nitrogen	116-124	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	200-203
22722744-0	2012	Comprehensive characterization of the N-glycosylation status of CD44s by use of multiple mass spectrometry-based techniques.	Nitrogen	38-39	CD44 molecule (Indian blood group)	Homo sapiens	64-68
22722744-9	2012	This is the first comprehensive report of the N-glycosylation of CD44s.	Nitrogen	46-47	CD44 molecule (Indian blood group)	Homo sapiens	65-69
22674433-5	2012	When cisplatin-containing liposomes mix with 5"-GMP-embedded liposomes or liposomes with 9-EtG, the N7 nitrogen atom of 5"-GMP or 9-EtG binds the cisplatin, thus replacing the "leaving groups" and forming a bisadduct.	Nitrogen	103-111	5'-nucleotidase, cytosolic II	Homo sapiens	48-51
22674433-5	2012	When cisplatin-containing liposomes mix with 5"-GMP-embedded liposomes or liposomes with 9-EtG, the N7 nitrogen atom of 5"-GMP or 9-EtG binds the cisplatin, thus replacing the "leaving groups" and forming a bisadduct.	Nitrogen	103-111	5'-nucleotidase, cytosolic II	Homo sapiens	123-126
22846176-4	2012	RESULTS: Independently of the initial concentration of the nitrogen source, glucose transport capacity is maximal during the early stages of fermentation and presumably sustained by the low-affinity and high-capacity glucose transporter Hxt1p.	Nitrogen	59-67	hexose transporter HXT1	Saccharomyces cerevisiae S288C	237-242
22607976-3	2012	We report here the cryptic N-glycosylation site as a recognition signal for unfolding of a natively nonglycosylated protein, transthyretin (TTR), involved in familial amyloidosis.	Nitrogen	27-28	transthyretin	Homo sapiens	125-138
22607976-3	2012	We report here the cryptic N-glycosylation site as a recognition signal for unfolding of a natively nonglycosylated protein, transthyretin (TTR), involved in familial amyloidosis.	Nitrogen	27-28	transthyretin	Homo sapiens	140-143
22607976-4	2012	Folding and ER-associated degradation (ERAD) perturbation analyses revealed that prolonged TTR unfolding induces externalization of cryptic N-glycosylation site and triggers STT3B-dependent posttranslational N-glycosylation.	Nitrogen	140-141	transthyretin	Homo sapiens	91-94
22607976-4	2012	Folding and ER-associated degradation (ERAD) perturbation analyses revealed that prolonged TTR unfolding induces externalization of cryptic N-glycosylation site and triggers STT3B-dependent posttranslational N-glycosylation.	Nitrogen	208-209	transthyretin	Homo sapiens	91-94
22753898-6	2012	In their view, PSEN1 mediates the N-glycosylation of V0a1 in the endoplasmic reticulum (ER); consequently, PSEN deficiency prevents V0a1 glycosylation, compromising the delivery of unglycosylated V0a1 to lysosomes, ultimately impairing V-ATPase function and lysosomal acidification.	Nitrogen	18-19	Vacuolar H[+] ATPase 100kD subunit 1	Drosophila melanogaster	53-57
22753898-6	2012	In their view, PSEN1 mediates the N-glycosylation of V0a1 in the endoplasmic reticulum (ER); consequently, PSEN deficiency prevents V0a1 glycosylation, compromising the delivery of unglycosylated V0a1 to lysosomes, ultimately impairing V-ATPase function and lysosomal acidification.	Nitrogen	18-19	Vacuolar H[+] ATPase 100kD subunit 1	Drosophila melanogaster	132-136
22496396-5	2012	CYP2C9 and CYP2C19 were the primary enzymes responsible for formation of the N-hydroxylated metabolite.	Nitrogen	77-78	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	11-18
22215283-2	2012	One way to reduce nitrogen excretion and emissions is supplementing dietary trace minerals to inhibit the activity of microbial uricase, a key enzyme converting nitrogen compounds in the manure into ammonia.	Nitrogen	18-26	urate oxidase (pseudogene)	Homo sapiens	128-135
22215283-2	2012	One way to reduce nitrogen excretion and emissions is supplementing dietary trace minerals to inhibit the activity of microbial uricase, a key enzyme converting nitrogen compounds in the manure into ammonia.	Nitrogen	161-169	urate oxidase (pseudogene)	Homo sapiens	128-135
22387313-0	2012	N-glycosylation of the mammalian dipeptidyl aminopeptidase-like protein 10 (DPP10) regulates trafficking and interaction with Kv4 channels.	Nitrogen	0-1	potassium voltage-gated channel subfamily C member 1	Homo sapiens	126-129
22349139-11	2012	Assays with recombinant CYPs verified that the N-demethylation is catalysed by CYP3A4, CYP2C19 and CYP2B6.	Nitrogen	47-48	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	87-94
22231730-7	2012	Notably, the expression of Dad1 protein, which is involved in protein N-glycosylation, was significantly increased in septic patients at d 10 after trauma.	Nitrogen	0-1	defender against cell death 1	Homo sapiens	27-31
22266355-1	2012	Flavin-containing monooxygenase (FMO) 5 belongs to a family of enzymes that catalyze the oxygenation of nucleophilic N- and S-containing compounds.	Nitrogen	117-118	flavin containing dimethylaniline monoxygenase 5	Homo sapiens	0-39
22412605-1	2012	In the structure of the title compound, C(14)H(12)ClNO, the ortho-Cl atom in the benzoyl ring is positioned syn to the C=O bond, while the meta-methyl group in the aniline ring is positioned anti to the N-H bond.	Nitrogen	52-53	synemin	Homo sapiens	108-111
22262650-1	2012	In a cell-based assay for novel inhibitors, we have discovered that two glycosides of 5-thiomannose, each containing an interglycosidic nitrogen atom, prevented the correct zymogen processing of the prohormone proopiomelanocortinin (POMC) and the transcription factor sterol-regulatory element-binding protein-2 (SREBP-2) in mouse pituitary cells and Chinese hamster ovary (CHO) cells, respectively.	Nitrogen	136-144	sterol regulatory element binding factor 2	Mus musculus	268-311
22262650-1	2012	In a cell-based assay for novel inhibitors, we have discovered that two glycosides of 5-thiomannose, each containing an interglycosidic nitrogen atom, prevented the correct zymogen processing of the prohormone proopiomelanocortinin (POMC) and the transcription factor sterol-regulatory element-binding protein-2 (SREBP-2) in mouse pituitary cells and Chinese hamster ovary (CHO) cells, respectively.	Nitrogen	136-144	sterol regulatory element binding factor 2	Mus musculus	313-320
21864230-11	2012	The more potent nitrogen-containing BPs inhibit FPPS, a key enzyme in the mevalonate pathway.	Nitrogen	16-24	farnesyl diphosphate synthase	Homo sapiens	48-52
22745569-11	2012	Unfortunately, due to the increasing world population, overfishing of the seas and generally low amounts of n-3 PUFA in major oil crops, there is a demand for new sources of n-3 PUFA.	Nitrogen	1-2	pumilio RNA binding family member 3	Homo sapiens	112-116
22745569-11	2012	Unfortunately, due to the increasing world population, overfishing of the seas and generally low amounts of n-3 PUFA in major oil crops, there is a demand for new sources of n-3 PUFA.	Nitrogen	1-2	pumilio RNA binding family member 3	Homo sapiens	178-182
22629982-0	2012	The effects of nitrogen bonding on hardness of AIN/CrN multilayer hard coatings.	Nitrogen	15-23	crooked neck pre-mRNA splicing factor 1	Homo sapiens	51-54
22629982-4	2012	Many broken nitrogen bonds were formed by decreasing the bilayer thickness of AIN/CrN multilayer coatings.	Nitrogen	12-20	crooked neck pre-mRNA splicing factor 1	Homo sapiens	82-85
22629982-5	2012	Existence of optimum AIN/CrN multilayer coatings thickness for maximum hardness could be explained by the competition of softening by the formation of broken nitrogen bonds and strengthening induced by decreasing bilayer thickness.	Nitrogen	158-166	crooked neck pre-mRNA splicing factor 1	Homo sapiens	25-28
22630005-0	2012	Hardness and nitrogen bonding structure of AlxTi1-xN/CrN multilayer hard coating.	Nitrogen	13-21	crooked neck pre-mRNA splicing factor 1	Homo sapiens	53-56
22630005-4	2012	However, the hardness of Al0.25Ti0.75N/CrN multilayer, having high Ti contents, increased by the formation of many Ti-N bond again instead of Al-N bond.	Nitrogen	37-38	crooked neck pre-mRNA splicing factor 1	Homo sapiens	39-42
22630005-5	2012	From these results, we found that linear crack propagation behavior was dominated by broken nitrogen bonds in the AlxTi1-xN/CrN multilayer coatings.	Nitrogen	92-100	crooked neck pre-mRNA splicing factor 1	Homo sapiens	124-127
22259503-1	2012	In the title compound, C(11)H(12)ClNO(3), the conformation of the N-H bond in the amide segment is syn with respect to the ortho-Cl atom.	Nitrogen	35-36	synemin	Homo sapiens	99-102
23231391-9	2012	Different families of nitrogen and oxygen heterocycles, such as pyrazoles, hydrazinylthiazoles, xanthones, coumarins or chromones have also been extensively used as scaffolds in medicinal chemistry programs for searching novel MAO-B inhibitors.	Nitrogen	22-30	monoamine oxidase B	Homo sapiens	227-232
23231391-10	2012	Nitrogen derivatives play a key role in this subject with several studies pointing out hydrazines, thiazoles or indoles as important scaffolds for the development of novel MAO-B inhibitors.	Nitrogen	0-8	monoamine oxidase B	Homo sapiens	172-177
23231391-11	2012	This review comprises an overview of the state of the art on the actual pharmacological therapy for PD followed by a specific focus on the discovery and development of nitrogen-based heterocyclic compounds analogues as promising MAO-B inhibitors.	Nitrogen	168-176	monoamine oxidase B	Homo sapiens	229-234
22240840-0	2012	The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells.	Nitrogen	15-16	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	84-90
22240840-5	2012	An immunoblot analysis of whole cell lysate (S9) fractions with or without treatment with an endoglycosidase revealed that UGT2B7 was N-glycosylated at Asn-68 and Asn-315 but not Asn-67.	Nitrogen	134-135	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	123-129
22240840-7	2012	These results suggest that N-glycosylation differentially affects the glucuronidation of AZT and morphine by human UGT2B7.	Nitrogen	27-28	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	115-121
22101279-1	2012	The NatB complex, Nat5/Mdm20 acetyltransferase mediates N-acetylation to control cell cycle progression and actin dynamics in yeast.	Nitrogen	4-5	peptide alpha-N-acetyltransferase subunit NAT5	Saccharomyces cerevisiae S288C	18-22
20858066-6	2012	Two novel compounds we report (MP1 and MP2) covalently link ibuprofen and ketoprofen directly to the amide nitrogen of n-acetyl-glucosamine (NAG); the other compound (MP3) covalently links ibuprofen to the amide nitrogen, using a short chain acetyl linker.	Nitrogen	107-115	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	Homo sapiens	31-34
23189196-9	2012	Finally, the implications that the presence of different N-terminals in the beta subunit could have on MAT II behavior are discussed in light of the recent identification of several splicing forms of this subunit in hepatoma cells.	Nitrogen	57-58	methionine adenosyltransferase 2B	Homo sapiens	103-109
22970294-9	2012	Mannose rich N-glycosylated synaptophysin was detected by treating retinal lysates with endoglycosidase H followed by immunoblot analysis.	Nitrogen	13-14	synaptophysin	Rattus norvegicus	28-41
22905317-4	2012	Scanning tunneling microscopy and spectroscopy (STM and STS) of NG revealed the presence of localized states in the conduction band induced by N(2)(AA)-doping, which was confirmed by ab initio calculations.	Nitrogen	143-147	sulfotransferase family 1A member 3	Homo sapiens	48-51
22121915-2	2011	The stepwise nature of the [3 + 2] cycloaddition reactions of N-metalated azomethine ylides has also been demonstrated by highly enantio- and diastereoselective syntheses of exo-5 and endo-8 from the respective syn-4 and anti-7 conjugate addition products in a one-pot tandem fashion.	Nitrogen	62-63	exonuclease 5	Homo sapiens	174-179
22121915-2	2011	The stepwise nature of the [3 + 2] cycloaddition reactions of N-metalated azomethine ylides has also been demonstrated by highly enantio- and diastereoselective syntheses of exo-5 and endo-8 from the respective syn-4 and anti-7 conjugate addition products in a one-pot tandem fashion.	Nitrogen	62-63	syntrophin gamma 1	Homo sapiens	211-216
22146389-4	2011	Here we report an experimental observation of an anomalous decoherence effect for the electron spin-1 of a nitrogen-vacancy centre in high-purity diamond at room temperature.	Nitrogen	107-115	spindlin 1	Homo sapiens	95-101
22091898-6	2011	Second-generation bisphosphonates are nitrogen-containing agents; these inhibit osteoclast vesicular trafficking, membrane ruffling, morphology, and cytoskeletal arrangement by inhibiting farnesyl diphosphate synthase in the mevalonate pathway.	Nitrogen	38-46	farnesyl diphosphate synthase	Homo sapiens	188-217
21949237-3	2011	PMM2 (mannose 6-phosphate   mannose 1-phosphate) and MPI (mannose 6-phosphate   fructose 6-phosphate) deficiencies reduce the metabolic flux of mannose 6-phosphate (Man-6-P) into glycosylation, resulting in unoccupied N-glycosylation sites.	Nitrogen	218-219	phosphomannomutase 2	Homo sapiens	0-4
22023129-7	2011	For all 3 species, inhibitors of CYP3A4, CYP2A6, CYP2C19, CYP2B6, and CYP2C9 diminished N-demethylation of ketamine.	Nitrogen	88-89	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	41-47
22023129-7	2011	For all 3 species, inhibitors of CYP3A4, CYP2A6, CYP2C19, CYP2B6, and CYP2C9 diminished N-demethylation of ketamine.	Nitrogen	88-89	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	49-56
21920023-3	2011	The aim of the present study was to determine whether human CTRC undergoes asparagine-linked (N-linked) glycosylation and to examine the role of this modification in CTRC folding and function.	Nitrogen	94-95	chymotrypsin C	Homo sapiens	60-64
21764901-3	2011	We have previously  demonstrated that CRES is present within the epididymal lumen as monomeric (14  and N-glycosylated 19-kd forms) as well as sodium dodecyl  sulfate-sensitive and sodium dodecyl sulfate-resistant  high-molecular mass complexes.	Nitrogen	104-105	cystatin 8 (cystatin-related epididymal spermatogenic)	Mus musculus	38-42
21752700-2	2011	The spectra of all these N-nitroso oximes reveal the presence of two isomers labelled as E (-NOH group is anti to N-N=O moiety) and Z (-NOH group is syn to N-N=O moiety) in solution and the coupling constants ruled out the possibility of normal chair conformation.	Nitrogen	25-26	synemin	Homo sapiens	149-152
21459495-0	2011	Brain histological changes in young mice submitted to diets with different ratios of n-6/n-3 polyunsaturated fatty acids during maternal pregnancy and lactation.	Nitrogen	4-5	notch 3	Mus musculus	89-92
21700369-4	2011	The nitrogen present in the central ring can act as hydrogen bond acceptors (HBA) whereas the amino group in the 4-position can act as a donor (HBD) or an HBA and the amino group in the 2-position can act as an HBD.	Nitrogen	4-12	HBD	Homo sapiens	211-214
21725556-5	2011	Specifically, nitrogen donor atoms of TTF-PPB adopt a cis-coordination but not in the equatorial plane, which is quite rare.	Nitrogen	14-22	histatin 1	Homo sapiens	42-45
21712387-3	2011	Here, we demonstrate that the interaction of human UNC119 (HRG4) with transducin is dependent on the N-acylation, but does not require the GTP-bound form of Galpha(t1).	Nitrogen	52-53	unc-119 lipid binding chaperone	Homo sapiens	59-63
21757347-0	2011	Synthesis, structure-activity relationship and biological evaluation of novel N-substituted matrinic acid derivatives as host heat-stress cognate 70 (Hsc70) down-regulators.	Nitrogen	78-79	heat shock protein family A (Hsp70) member 8	Homo sapiens	126-148
21757347-0	2011	Synthesis, structure-activity relationship and biological evaluation of novel N-substituted matrinic acid derivatives as host heat-stress cognate 70 (Hsc70) down-regulators.	Nitrogen	78-79	heat shock protein family A (Hsp70) member 8	Homo sapiens	150-155
21757347-2	2011	Taking Hsc70 as a target against HBV, 26 novel N-substituted matrinic acid analogs were designed, synthesized and evaluated for their regulation of Hsc70 mRNA expression with 1 as the lead.	Nitrogen	47-48	heat shock protein family A (Hsp70) member 8	Homo sapiens	148-153
21757347-3	2011	The SAR analysis revealed that (i) the carboxyl group at the 11-position was required for activity; (ii) introducing of a substituent on the nitrogen atom at the 12-position of 3, especially substituted benzyl, might significantly improve the activity.	Nitrogen	141-149	sarcosine dehydrogenase	Homo sapiens	4-7
21605051-5	2011	First, the transport of n-3 PUFA across the blood-brain barrier is underscored based on preclinical data.	Nitrogen	14-15	pumilio RNA binding family member 3	Homo sapiens	28-32
21806764-6	2011	Predictors of cTnI were age, history of hypercholesterolemia, blood urea nitrogen level, pulmonary edema, and requirement for mechanical ventilation.	Nitrogen	73-81	troponin I3, cardiac type	Homo sapiens	14-18
21593171-4	2011	env genes of viruses transmitted to infants IP, but not IU, encoded Env proteins that were shorter and had fewer putative N-linked glycosylation sites in the V1-V5 region than matched maternal sequences.	Nitrogen	122-123	endogenous retrovirus group K member 20	Homo sapiens	0-3
21593171-4	2011	env genes of viruses transmitted to infants IP, but not IU, encoded Env proteins that were shorter and had fewer putative N-linked glycosylation sites in the V1-V5 region than matched maternal sequences.	Nitrogen	122-123	endogenous retrovirus group K member 20	Homo sapiens	68-71
21684752-4	2011	Although the N-phenethyl substituent showed much greater affinity for mu- and kappa-opioid receptors than their N-methyl relatives (e.g., K(i)=167 nM and 171 nM at mu- and kappa-receptors vs &gt;2800 and 7500 nM for the N-methyl ortho-a oxide-bridged phenylmorphan), the a-isomers were not examined further because of their relatively low affinity.	Nitrogen	13-14	opioid receptor kappa 1	Homo sapiens	70-100
21497677-7	2011	A major advance was the discovery that the anti-resorptive effects of the nitrogen-containing bisphosphonates (including alendronate, risedronate, ibandronate, and zoledronate) on osteoclasts appear to result from their potency as inhibitors of the enzyme farnesyl pyrophosphate synthase (FPPS), a key branch-point enzyme in the mevalonate pathway.	Nitrogen	74-82	farnesyl diphosphate synthase	Homo sapiens	256-287
21497677-7	2011	A major advance was the discovery that the anti-resorptive effects of the nitrogen-containing bisphosphonates (including alendronate, risedronate, ibandronate, and zoledronate) on osteoclasts appear to result from their potency as inhibitors of the enzyme farnesyl pyrophosphate synthase (FPPS), a key branch-point enzyme in the mevalonate pathway.	Nitrogen	74-82	farnesyl diphosphate synthase	Homo sapiens	289-293
21561106-0	2011	Cell type-specific and site directed N-glycosylation pattern of FcgammaRIIIa.	Nitrogen	37-38	Fc gamma receptor IIIa	Homo sapiens	64-76
21593147-2	2011	We previously observed that escape from humoral immunity, both at the individual and at a population level, coincided with longer variable loops and an increased number of potential N-linked glycosylation sites (PNGS) in the viral envelope glycoprotein (Env) and, in particular, in variable regions 1 and 2 (V1V2).	Nitrogen	182-183	endogenous retrovirus group K member 20	Homo sapiens	231-252
21324343-0	2011	Cytofluorimetric evaluation of N-glycolylated GM3 ganglioside expression on murine leukocytes.	Nitrogen	31-32	granulocyte macrophage antigen 3	Mus musculus	46-49
21324343-3	2011	On the contrary of other gangliosides, differential expression of the N-glycolylated variant of GM3 (NGcGM3) on murine leukocytes has received limited attention.	Nitrogen	70-71	granulocyte macrophage antigen 3	Mus musculus	96-99
21511948-2	2011	N-Linked glycosylation of RAGE plays an important role in the regulation of ligand binding.	Nitrogen	0-1	advanced glycosylation end-product specific receptor	Homo sapiens	26-30
21511948-12	2011	Therefore, the G82S polymorphism promotes N-linked glycosylation of Asn(81), which has implications for the structure of the ligand binding region of RAGE and might explain the enhanced function associated with the G82S polymorphic RAGE variant.	Nitrogen	42-43	advanced glycosylation end-product specific receptor	Homo sapiens	150-154
21511948-12	2011	Therefore, the G82S polymorphism promotes N-linked glycosylation of Asn(81), which has implications for the structure of the ligand binding region of RAGE and might explain the enhanced function associated with the G82S polymorphic RAGE variant.	Nitrogen	42-43	advanced glycosylation end-product specific receptor	Homo sapiens	232-236
21489996-2	2011	N-Linked glycosylation of the carbohydrate recognition domain (CRD) of pSP-D contributes to the high affinity of this collectin for IAV.	Nitrogen	0-1	surfactant protein D	Homo sapiens	71-76
21699338-4	2011	We predict that the multitransition of a nitrogen-vacancy center spin-1 in diamond can have longer coherence time than the single transitions, even though the former suffers twice stronger noises from the nuclear spin bath than the latter.	Nitrogen	41-49	spindlin 1	Homo sapiens	65-71
21183928-8	2011	RESULTS: As a result of infusion of recombinant VEGF(121) autoantibody-induced hypertension (systolic blood pressure) was reduced from 159 +- 5 to 124 +- 5 mm Hg, proteinuria from 111 +- 16 to 40 +- 5 mg protein/mg creatinine and blood urea nitrogen levels from 31 +- 1 mg/dl to 18 +- 2 mg/dl, P &lt; 0.05.	Nitrogen	241-249	vascular endothelial growth factor A	Mus musculus	48-52
21780581-5	2011	The average of NAP of nitrogen and phosphorus are 23.55 mg/kg and 11.72 mg/kg respectively.	Nitrogen	22-30	catenin beta like 1	Homo sapiens	15-18
21780581-6	2011	The NAP of nitrogen and phosphorus are higher in the area of serious pollution.	Nitrogen	11-19	catenin beta like 1	Homo sapiens	4-7
21357487-2	2011	BacA of Sinorhizobium meliloti plays an essential role in the establishment of nitrogen-fixing symbioses with Medicago plants, where it is involved in peptide import and in the addition of very-long-chain fatty acids (VLCFA) to lipid A of lipopolysaccharide (LPS).	Nitrogen	79-87	peptide antibiotic transporter SbmA	Sinorhizobium fredii NGR234	0-4
21420384-0	2011	Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells.	Nitrogen	125-133	farnesyl diphosphate synthase	Homo sapiens	55-86
21420384-1	2011	A class of drugs successfully used for treatment of metabolic bone diseases is the nitrogen-containing bisphosphonates (N-BPs), which act by inhibiting the vital enzyme, farnesyl pyrophosphate synthase (FPPS), of the mevalonate pathway.	Nitrogen	83-91	farnesyl diphosphate synthase	Homo sapiens	170-201
21420384-1	2011	A class of drugs successfully used for treatment of metabolic bone diseases is the nitrogen-containing bisphosphonates (N-BPs), which act by inhibiting the vital enzyme, farnesyl pyrophosphate synthase (FPPS), of the mevalonate pathway.	Nitrogen	83-91	farnesyl diphosphate synthase	Homo sapiens	203-207
21388211-2	2011	Depending on the position of the C-Zn bond relative to the nitrogen (position 2 vs position 4), the stereoselectivity of the coupling can be directed toward either the trans- or cis-2,4-disubstituted products.	Nitrogen	59-67	suppressor of cytokine signaling 2	Homo sapiens	178-183
21253721-10	2011	These findings could be fundamental to improve understanding of the importance of AOB and AOA in nitrogen and other nutrients cycle in wetland ecosystems.	Nitrogen	97-105	aprataxin	Homo sapiens	90-93
21145999-4	2011	The nitrogen-containing bisphosphonates, such as alendronate, act as inhibitors of farnesyl-pyrophosphate synthase, which leads to inhibition of the prenylation of many intracellular signaling proteins.	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	83-114
21236358-7	2011	The approach presented here thus provides a protocol for the comprehensive and concomitant assessment of the generation capacity of n-3 and n-6 PUFA-derived lipid metabolites as well as thromboxanes and prostaglandins in human and murine blood samples.	Nitrogen	18-19	pumilio RNA binding family member 3	Homo sapiens	144-148
21608228-11	2011	The positive expressions of MMP-2 and MMP-9 in the XTSJD group and the OH group was significantly lower than that in the NS group (P &lt;0.01).	Nitrogen	121-123	matrix metallopeptidase 2	Mus musculus	28-33
21222436-2	2011	The catalytic mechanism of ferrochelatase has been proposed to involve the stabilization of a nonplanar porphyrin to present the pyrrole nitrogens to the metal ion substrate.	Nitrogen	137-146	ferrochelatase	Mus musculus	27-41
20451480-2	2011	The main human dietary source for n-3LC-PUFA is fish and seafood, and over 50% of global fish production is currently supplied by aquaculture.	Nitrogen	7-8	pumilio RNA binding family member 3	Homo sapiens	40-44
21118821-4	2011	This review will mainly focus on these recent advances in the molecular knowledge of N sensing in plants such as the dual function of the nitrate transporter CHL1, the roles of the transcription factors LBD37/38/39 and NLP7 or of the CIPK8/23 kinases, as well as the implication of small RNAs, which are at last opening doors for future research in this field.	Nitrogen	85-86	nitrate transporter 1.1	Arabidopsis thaliana	158-162
21118821-4	2011	This review will mainly focus on these recent advances in the molecular knowledge of N sensing in plants such as the dual function of the nitrate transporter CHL1, the roles of the transcription factors LBD37/38/39 and NLP7 or of the CIPK8/23 kinases, as well as the implication of small RNAs, which are at last opening doors for future research in this field.	Nitrogen	85-86	NIN like protein 7	Arabidopsis thaliana	219-223
21456295-3	2011	In gel retardation assay, PAMAM-dexamethasone conjugate (PAM-Dex)/DOPE liposome/DNA complex was completely retarded at 8:1 N/P (nitrogen/phosphate) ratio.	Nitrogen	128-136	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	26-29
22187667-8	2011	Next to Cl(-) ion is a hydrogen bonded water molecule W-7" which in turn is hydrogen bonded to W-8" and N atom of SCN(-).	Nitrogen	0-1	sorcin	Homo sapiens	114-117
22174631-10	2011	The present paper brings evidence that independently on the mode of P-gp expression (selection with drugs or transfection with a gene encoding P-gp) in L1210 cells, tunicamycin induces inhibition of N-glycosylation of this protein, without altering its function as plasma membrane drug efflux pump.	Nitrogen	199-200	phosphoglycolate phosphatase	Mus musculus	143-147
21833870-4	2011	The basics of this technique are discussed along with examples of how MCD spectroscopy has been successfully used to elucidate the metal clusters of Nif proteins from nitrogen-fixing bacteria.	Nitrogen	167-175	S100 calcium binding protein A9	Homo sapiens	149-152
21216945-7	2011	Tap46 depletion reproduced the signature phenotypes of TOR inactivation, such as dramatic repression of global translation and activation of autophagy and nitrogen mobilization, indicating that Tap46 may act as a positive effector of TOR signaling in controlling those processes.	Nitrogen	155-163	2A phosphatase associated protein of 46 kD	Arabidopsis thaliana	0-5
21216945-7	2011	Tap46 depletion reproduced the signature phenotypes of TOR inactivation, such as dramatic repression of global translation and activation of autophagy and nitrogen mobilization, indicating that Tap46 may act as a positive effector of TOR signaling in controlling those processes.	Nitrogen	155-163	2A phosphatase associated protein of 46 kD	Arabidopsis thaliana	194-199
22174908-1	2011	Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, were identified in Maricaulis maris and several other bacteria.	Nitrogen	0-1	N-acetylglutamate synthase	Homo sapiens	55-59
22174908-1	2011	Novel bifunctional N-acetylglutamate synthase/kinases (NAGS/K) that catalyze the first two steps of arginine biosynthesis and are homologous to vertebrate N-acetylglutamate synthase (NAGS), an essential cofactor-producing enzyme in the urea cycle, were identified in Maricaulis maris and several other bacteria.	Nitrogen	0-1	N-acetylglutamate synthase	Homo sapiens	183-187
22102866-6	2011	GNC and CGA1 were found to modify the expression of chloroplast localized GLUTAMATE SYNTHASE (GLU1/Fd-GOGAT), which is the primary factor controlling nitrogen assimilation in green tissue.	Nitrogen	150-158	GATA type zinc finger transcription factor family protein	Arabidopsis thaliana	0-3
22102866-6	2011	GNC and CGA1 were found to modify the expression of chloroplast localized GLUTAMATE SYNTHASE (GLU1/Fd-GOGAT), which is the primary factor controlling nitrogen assimilation in green tissue.	Nitrogen	150-158	cytokinin-responsive gata factor 1	Arabidopsis thaliana	8-12
22102866-10	2011	Despite some evidence for partial divergence, results indicate that regulation of both GNC and CGA1 by light, nitrogen, cytokinin, and GA acts to modulate nitrogen assimilation, chloroplast development and starch production.	Nitrogen	110-118	GATA type zinc finger transcription factor family protein	Arabidopsis thaliana	87-90
22102866-10	2011	Despite some evidence for partial divergence, results indicate that regulation of both GNC and CGA1 by light, nitrogen, cytokinin, and GA acts to modulate nitrogen assimilation, chloroplast development and starch production.	Nitrogen	110-118	cytokinin-responsive gata factor 1	Arabidopsis thaliana	95-99
22102866-10	2011	Despite some evidence for partial divergence, results indicate that regulation of both GNC and CGA1 by light, nitrogen, cytokinin, and GA acts to modulate nitrogen assimilation, chloroplast development and starch production.	Nitrogen	155-163	GATA type zinc finger transcription factor family protein	Arabidopsis thaliana	87-90
22102866-10	2011	Despite some evidence for partial divergence, results indicate that regulation of both GNC and CGA1 by light, nitrogen, cytokinin, and GA acts to modulate nitrogen assimilation, chloroplast development and starch production.	Nitrogen	155-163	cytokinin-responsive gata factor 1	Arabidopsis thaliana	95-99
21625599-6	2011	To this end, we have constructed mutants of human tyrosinase in which its seven N-glycosylation sites were deleted.	Nitrogen	80-81	tyrosinase	Homo sapiens	50-60
20831856-0	2010	gamma-Glutamyl transpeptidase is a heavily N-glycosylated heterodimer in HepG2 cells.	Nitrogen	43-44	inactive glutathione hydrolase 2	Homo sapiens	0-29
20831856-8	2010	Three independent, experimental approaches demonstrate that GGT in HepG2 cells is comprised of two subunits that are more heavily N-glycosylated than GGT from normal human liver tissue.	Nitrogen	130-131	inactive glutathione hydrolase 2	Homo sapiens	60-63
20868657-3	2010	Furthermore, we investigated whether feeding a diet of n-3 PUFA ethyl-eicosapentaenoate (E-EPA) to these mice can attenuate the MPP(+) induced changes in brain PUFA content and expression of cPLA2 and COX-2, and attenuate MPP(+) induced changes in neurotransmitters and metabolites and apoptotic markers, bax, bcl-2 and caspase-3.	Nitrogen	17-18	BCL2-associated X protein	Mus musculus	305-308
20868657-3	2010	Furthermore, we investigated whether feeding a diet of n-3 PUFA ethyl-eicosapentaenoate (E-EPA) to these mice can attenuate the MPP(+) induced changes in brain PUFA content and expression of cPLA2 and COX-2, and attenuate MPP(+) induced changes in neurotransmitters and metabolites and apoptotic markers, bax, bcl-2 and caspase-3.	Nitrogen	17-18	caspase 3	Mus musculus	320-329
20952643-4	2010	The results indicated that nitrogen limitation leads to an increase in ROS and that the superoxide anion is a minor component of the ROS, but there is increased activity of both Sod2p and Cta1p.	Nitrogen	27-35	superoxide dismutase SOD2	Saccharomyces cerevisiae S288C	178-183
20947347-5	2010	The ligand catalyst bound to avidin first catalyzed N-triazinylation of the epsilon-amino group of Lys111, and the resulting regenerated catalyst then catalyzed the reaction of Asp108 and CDMT.	Nitrogen	52-53	CYLD lysine 63 deubiquitinase	Homo sapiens	188-192
21589372-2	2010	The conformations of the N-H bonds with respect to their adjacent ortho-chlorine atoms are syn.	Nitrogen	25-26	synemin	Homo sapiens	91-94
20839183-4	2010	The versatility of this new nitrogen protecting group is illustrated with a new synthesis of Selegiline, a monoamine oxidase-B inhibitor marketed for the treatment of Parkinson"s disease.	Nitrogen	28-36	monoamine oxidase B	Homo sapiens	107-126
20713656-5	2010	Consistent with these observations, the UGT1A4 inhibitor hecogenin and the UGT2B7 substrate diclofenac potently inhibited the N- and O-glucuronidation of 1"-hydroxymidazolam in HLMs, respectively.	Nitrogen	126-127	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	75-81
20624874-7	2010	Lectin blot analysis indicated the presence of non-reducing terminal alpha2-6 and alpha2-3-linked sialic acid residues with penultimate beta-galactose residues on the N- and O-linked sugar chains of pADAMTS13, suggesting that pADAMTS13 is cleared from the circulation via the hepatic asialoglycoprotein receptor like other plasma glycoproteins.	Nitrogen	167-168	immunoglobulin binding protein 1	Homo sapiens	69-77
20739743-6	2010	The orientation of the spin current is found to be flipped if the flake is doped with N, O, or F atoms.	Nitrogen	86-87	spindlin 1	Homo sapiens	23-27
20877236-5	2010	Eupatilin and jaceosidin were also found to moderately inhibit CYP2C19-catalyzed [S]-mephenytoin 4"-hydroxylation, CYP2D6-catalyzed bufuralol 1"-hydroxylation, and CYP2C8-catalyzed amodiaquine N-deethylation.	Nitrogen	193-194	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	63-70
20629116-1	2010	A series of peptide-peptoid hybrids, containing N-substituted glycines, were synthesized based on the H-Aib-Val-Aib-Glu-Ile-Gln-Leu-Nle-His-Gln-Har-NH(2) (Har = Homoarginine) as the parent parathyroid hormone (1-11) analog.	Nitrogen	48-49	ANIB1	Homo sapiens	104-107
20629116-1	2010	A series of peptide-peptoid hybrids, containing N-substituted glycines, were synthesized based on the H-Aib-Val-Aib-Glu-Ile-Gln-Leu-Nle-His-Gln-Har-NH(2) (Har = Homoarginine) as the parent parathyroid hormone (1-11) analog.	Nitrogen	48-49	ANIB1	Homo sapiens	112-115
20660348-6	2010	A single-nucleotide polymorphism in the first short consensus repeat of Sle1c Crry introduced a novel N-linked glycosylation site likely responsible for this structural alteration.	Nitrogen	102-103	complement component (3b/4b) receptor 1-like	Mus musculus	78-82
20562225-2	2010	The results indicate that the genetic blockage of starch synthesis in the sta6 and sta7-10 mutants increases the accumulation of lipids on a cellular basis during nitrogen deprivation relative to that in the CC124 control as determined by conversion to fatty acid methyl esters.	Nitrogen	163-171	uncharacterized protein	Chlamydomonas reinhardtii	74-78
20574814-3	2010	This assignment strategy was demonstrated for (13)C/(15)N-labeled GB1 dissolved in (2)H(2)O.	Nitrogen	56-57	gamma-aminobutyric acid type B receptor subunit 1	Homo sapiens	66-69
20655849-1	2010	N-glycosylation of the I-like domain of beta1 integrin plays an essential role in integrin structure and function, and the altered sialylation of beta1 integrin regulates beta1 integrin binding to fibronectin.	Nitrogen	0-1	integrin subunit beta 1	Homo sapiens	40-54
20427718-11	2010	These data suggest that in mice fed NS-containing diet, upregulation of arterial A(1) receptor causes vasoconstriction via increased sEH and CYP4A proteins.	Nitrogen	36-38	epoxide hydrolase 2, cytoplasmic	Mus musculus	133-136
20427718-11	2010	These data suggest that in mice fed NS-containing diet, upregulation of arterial A(1) receptor causes vasoconstriction via increased sEH and CYP4A proteins.	Nitrogen	36-38	cytochrome P450, family 4, subfamily a, polypeptide 10	Mus musculus	141-146
19963017-2	2010	In our study we tested the N-Lost l-Phenylalanine Mustard (l-Pam).	Nitrogen	27-28	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	61-64
20444232-0	2010	Identification of a nitrate-responsive cis-element in the Arabidopsis NIR1 promoter defines the presence of multiple cis-regulatory elements for nitrogen response.	Nitrogen	145-153	nitrite reductase 1	Arabidopsis thaliana	70-74
19747152-0	2010	Synthetic strategies to a backbone-side chain cyclic SHP-1 N-SH2 ligand containing N-functionalized alkyl phosphotyrosine.	Nitrogen	59-60	protein tyrosine phosphatase non-receptor type 6	Homo sapiens	53-58
20520733-4	2010	Here, we present the experimentally-solved topological models for FIT1 and FIT2 using N-glycosylation site mapping and indirect immunofluorescence techniques.	Nitrogen	86-87	fat storage inducing transmembrane protein 2	Homo sapiens	75-79
20397666-3	2010	These complexes undergo syn-migratory insertion of the alkene into the Pd-N bond to yield observable (dppf)palladium(aryl)(pyrrolidin-2-yl-methyl) complexes 6.	Nitrogen	74-75	synemin	Homo sapiens	24-27
20130121-9	2010	Diseased p21-/- mice demonstrated worse albuminuria, more widespread glomerulosclerosis, and higher blood urea nitrogen compared with diseased p21+/+ mice.	Nitrogen	111-119	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	9-12
20138484-6	2010	We found that expression levels of HSP and Bcl-2 in fibroblasts were strongly dependent on the surface hydrophilicity and concentration of nitrogen-containing functional groups on the nanofiber matrices.	Nitrogen	139-147	heat shock protein 90 beta family member 2, pseudogene	Homo sapiens	35-38
20153391-6	2010	Of interest, a dimeric version of this cyclic peptide, N-Ac-CHAVDINGHAVDIC-NH(2), functions as an N-cadherin agonist.	Nitrogen	55-57	cadherin 2	Homo sapiens	98-108
20397209-2	2010	An aromatic peptide of N-(t-Boc)-terminated triphenylalanine is designed from a structural motif for the beta-amyloid associated with Alzheimer"s disease.	Nitrogen	23-24	BOC cell adhesion associated, oncogene regulated	Homo sapiens	28-31
20199105-4	2010	Preventing N-glycosylation abolishes binding of the beta(2) subunit to calnexin and results in the ER retention of the subunit.	Nitrogen	11-12	calnexin	Canis lupus familiaris	71-79
20199105-5	2010	Furthermore, the fully N-glycosylated beta(2) subunit is retained in the ER when glycan-calnexin interactions are prevented by castanospermine, showing that N-glycan-mediated calnexin binding is required for correct subunit folding.	Nitrogen	23-24	calnexin	Canis lupus familiaris	88-96
20199105-5	2010	Furthermore, the fully N-glycosylated beta(2) subunit is retained in the ER when glycan-calnexin interactions are prevented by castanospermine, showing that N-glycan-mediated calnexin binding is required for correct subunit folding.	Nitrogen	23-24	calnexin	Canis lupus familiaris	175-183
20225831-6	2010	In both series the aqua ligands are hydrogen bonded to the nitrogen atoms from both the terminal CN(-) groups and the hmt molecules.	Nitrogen	59-67	histamine N-methyltransferase	Homo sapiens	118-121
20299227-5	2010	Unlike most nitrogen-containing bisphosphonates which target farnesyl pyrophosphate synthase, experimental and theoretical investigations suggest that the activity of our derivatives may be related to different mechanisms.	Nitrogen	12-20	farnesyl diphosphate synthase	Homo sapiens	61-92
20127679-5	2010	By deletion of the carbohydrate-recognition domain region and mutation of crucial amino acids involved in carbohydrate-recognition of LSECtin and by inhibition of the N-linked glycosylation of CD44, we further demonstrated that the interaction between CD44 and LSECtin is dependent on protein-glycan recognition.	Nitrogen	167-168	CD44 molecule (Indian blood group)	Homo sapiens	193-197
20178386-3	2010	The C-terminal domain of Stt3p has been proposed to be the catalytic domain of yeast oligosaccharyl transferase (OT), a multisubunit membrane-associated enzyme complex catalyzing N-glycosylation, which is an essential and highly conserved protein modification.	Nitrogen	179-180	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	25-30
20209559-1	2010	Golgi alpha-mannosidase II (GMII) is a key enzyme in the N-glycosylation pathway and is a potential target for cancer chemotherapy.	Nitrogen	57-58	alpha-Mannosidase class II a	Drosophila melanogaster	28-32
20190456-4	2010	The immobilized cytochrome-c column integrated into LC-NMR was used to characterize the reaction product formed on N-demethylation by measurement of (1)H-NMR.	Nitrogen	55-56	cytochrome c, somatic	Canis lupus familiaris	16-28
19921330-5	2010	Some proteins related with regulation of nitrogen assimilation pathways (glutamine synthetase), oxidative stress repairing (catalase), and protection (neutral trehalase and glycosyltransferase) could improve the effectiveness of cyanide biodegradation.	Nitrogen	41-49	glutamate--ammonia ligase	Klebsiella oxytoca	73-93
20007296-6	2010	CYP3A activity was also assessed by the N-demethylation of erythromycin.	Nitrogen	40-41	cytochrome P450, family 3, subfamily a, polypeptide 11	Mus musculus	0-5
20045315-3	2010	SAR studies at the lactam nitrogen of the pharmacophore have suggested that a secondary or tertiary amine is important for cellular potency.	Nitrogen	26-34	sarcosine dehydrogenase	Homo sapiens	0-3
20002318-6	2010	Contrary to previous studies, leaf nitrogen concentration was similar in C(4) and C(3) types.	Nitrogen	35-43	complement C3	Homo sapiens	82-86
20532736-1	2010	P(II) signalling proteins constitute a large superfamily of signal perception and transduction proteins, which is represented in all domains of life and whose members play central roles in coordinating nitrogen assimilation.	Nitrogen	202-210	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	0-5
20532736-2	2010	Generally, P(II) proteins act as sensors of the cellular adenylylate energy charge and 2-oxoglutarate level, and in response to these signals, they regulate central nitrogen assimilatory processes at various levels of control (from nutrient transport to gene expression) through protein-protein interactions with P(II) receptor proteins.	Nitrogen	165-173	nitrogen regulatory P-II-like protein	Arabidopsis thaliana	11-16
19807734-7	2010	The expression level of IL-17 was correlated closely with clinical parameters such as haematuria, blood urea nitrogen level, SLE Disease Activity Index scores in both glomeruli and interstitium, urine protein level in glomeruli and serum creatinine and creatinine clearance levels in interstitium.	Nitrogen	109-117	interleukin 17A	Homo sapiens	24-29
19941472-6	2010	In vitro studies have suggested that the neuroprotective role of Nb may be due to its ability to scavenge reactive oxygen (ROS) and nitrogen (RNS) species.	Nitrogen	132-140	neuroglobin	Homo sapiens	65-67
19697108-4	2010	Of the three possible monocations, only two kinds of monocations, MC1 (formed by protonation of pyridine ring nitrogen) and MC2 (formed by the protonation of imidazole nitrogen) are present in all the micelles (Scheme 1).	Nitrogen	168-176	melanocortin 5 receptor	Homo sapiens	124-127
20299767-3	2010	Contrary to conventional systems in which worm-like micelles are formed, the zero-shear viscosity of the micellar solution in the water/CGT-n/CTAB system with n=1.2 increases with the addition of cationic cosurfactant and once decreases after a maximum, then increases again and decreases after the second maximum.	Nitrogen	2-3	UDP glycosyltransferase 8	Homo sapiens	136-139
20113636-7	2010	Compared with the NS group, the expression of synaptophysin in the K and the PK groups decreased significantly 24 hrs and 14 days after administration (p&lt;0.05).	Nitrogen	18-20	synaptophysin	Rattus norvegicus	46-59
19801543-0	2009	N-Glycosylation regulates fibroblast growth factor receptor/EGL-15 activity in Caenorhabditis elegans in vivo.	Nitrogen	0-1	Myoblast growth factor receptor egl-15;Receptor protein-tyrosine kinase	Caenorhabditis elegans	60-66
19801543-4	2009	The C. elegans FGF receptor, EGL-15, is N-glycosylated in vivo, and genetic substitution of specific consensus N-glycosylation sites leads to defects in the maintenance of fluid homeostasis and differentiation of sex muscles, both of which are phenotypes previously associated with hyperactive EGL-15 signaling.	Nitrogen	40-41	Myoblast growth factor receptor egl-15;Receptor protein-tyrosine kinase	Caenorhabditis elegans	29-35
19801543-4	2009	The C. elegans FGF receptor, EGL-15, is N-glycosylated in vivo, and genetic substitution of specific consensus N-glycosylation sites leads to defects in the maintenance of fluid homeostasis and differentiation of sex muscles, both of which are phenotypes previously associated with hyperactive EGL-15 signaling.	Nitrogen	111-112	Myoblast growth factor receptor egl-15;Receptor protein-tyrosine kinase	Caenorhabditis elegans	29-35
19666988-2	2009	After N-hydroxylation, they are O-acetylated by N-acetyltransferase 2 (NAT2) to electrophiles that form DNA adducts.	Nitrogen	6-7	N-acetyltransferase 2	Homo sapiens	48-69
19666988-2	2009	After N-hydroxylation, they are O-acetylated by N-acetyltransferase 2 (NAT2) to electrophiles that form DNA adducts.	Nitrogen	6-7	N-acetyltransferase 2	Homo sapiens	71-75
19123069-0	2009	Influence of nitrogen on the expression of TaDof1 transcription factor in wheat and its relationship with photo synthetic and ammonium assimilating efficiency.	Nitrogen	13-21	dof zinc finger protein 4	Triticum aestivum	43-49
19123069-6	2009	Gene expression profile of a Dof transcription factor (TaDof1 of wheat) was also included in the study to assess its role in nitrogen metabolism.	Nitrogen	125-133	dof zinc finger protein 4	Triticum aestivum	55-61
19123069-7	2009	Densitometry analysis at S(2) and S(3) stage of wheat spikes of both the wheat varieties grown at different nitrogen treatments showed that TaDof1 expression was up-regulated in low nitrogen treatment.	Nitrogen	108-116	dof zinc finger protein 4	Triticum aestivum	140-146
19123069-7	2009	Densitometry analysis at S(2) and S(3) stage of wheat spikes of both the wheat varieties grown at different nitrogen treatments showed that TaDof1 expression was up-regulated in low nitrogen treatment.	Nitrogen	182-190	dof zinc finger protein 4	Triticum aestivum	140-146
19123069-8	2009	In S(3) stage, in high protein content wheat variety UP-2644, TaDof1 expression was elevated in low and normal nitrogen treatment as compared to high nitrogen treatment.	Nitrogen	111-119	dof zinc finger protein 4	Triticum aestivum	62-68
21578345-2	2009	The conformation of the N-H bond is anti to the meta-methyl substituent in the aniline ring in the first mol-ecule and syn in the second mol-ecule.	Nitrogen	24-25	synemin	Homo sapiens	119-122
19692571-4	2009	Biotinylation and dye uptake assays indicated that all three pannexins, as well as the N-glycosylation-defective mutants of Panx1 and Panx3, can traffic to the cell surface and form functional single-membrane channels.	Nitrogen	87-88	pannexin 1	Homo sapiens	124-129
19692571-4	2009	Biotinylation and dye uptake assays indicated that all three pannexins, as well as the N-glycosylation-defective mutants of Panx1 and Panx3, can traffic to the cell surface and form functional single-membrane channels.	Nitrogen	87-88	pannexin 3	Homo sapiens	134-139
19774086-7	2009	CONCLUSIONS/SIGNIFICANCE: Transcription analysis and gene silencing of LKR/SDH indicated that tick LKR/SDH enzyme plays not only important roles in egg production, reproduction and development of the tick, but also in carbon, nitrogen and water balance, crucial physiological processes for the survival of ticks.	Nitrogen	226-234	aminoadipate-semialdehyde synthase	Homo sapiens	71-78
19774086-7	2009	CONCLUSIONS/SIGNIFICANCE: Transcription analysis and gene silencing of LKR/SDH indicated that tick LKR/SDH enzyme plays not only important roles in egg production, reproduction and development of the tick, but also in carbon, nitrogen and water balance, crucial physiological processes for the survival of ticks.	Nitrogen	226-234	aminoadipate-semialdehyde synthase	Homo sapiens	99-106
20448974-1	2009	A general protocol for removing Boc groups from various types of nitrogen is reported and a preliminary investigation of the reaction mechanism indicates that water acts as a dual acid/base catalyst at elevated temperature.	Nitrogen	65-73	BOC cell adhesion associated, oncogene regulated	Homo sapiens	32-35
19574222-2	2009	The transcriptional activator Put3p allows yeast cells to utilize proline as a nitrogen source through expression of the PUT1 and PUT2 genes.	Nitrogen	79-87	Put3p	Saccharomyces cerevisiae S288C	30-35
19595734-16	2009	Our report may provide clues regarding the nature of the biological amidase substrate(s) of Nit1 (another member of the Nit family), which is a well-established tumor suppressor protein), and emphasizes a) the crucial role of Nit2 in nitrogen and sulfur metabolism, and b) the possible link of Nit2 to cancer biology.	Nitrogen	234-242	nitrilase 1	Homo sapiens	92-96
19810397-5	2009	The potency of the various nitrogen-containing bisphosphonates is dependent on a number of factors including bone binding, zeta potential and inhibition of the enzyme farnesyl pyrophosphate synthase.	Nitrogen	27-35	farnesyl diphosphate synthase	Homo sapiens	167-198
19621239-4	2009	Several structural genes of flavonoid metabolism including CHS (chalcone synthase), FLS1 (flavonol synthase 1) and ANS (anthocyanidin synthase) were induced in response to nitrogen depletion in wild type as well as in the egl3 and gl3 mutants.	Nitrogen	172-180	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	222-226
19621239-4	2009	Several structural genes of flavonoid metabolism including CHS (chalcone synthase), FLS1 (flavonol synthase 1) and ANS (anthocyanidin synthase) were induced in response to nitrogen depletion in wild type as well as in the egl3 and gl3 mutants.	Nitrogen	172-180	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	223-226
19633234-7	2009	The loss of nitrate induction in the two nrt1.1 mutants (nrg1 and chl1-5) was not explained by reduced nitrate uptake and was reversed by nitrogen deprivation.	Nitrogen	138-146	nitrate transporter 1.1	Arabidopsis thaliana	41-47
19633234-7	2009	The loss of nitrate induction in the two nrt1.1 mutants (nrg1 and chl1-5) was not explained by reduced nitrate uptake and was reversed by nitrogen deprivation.	Nitrogen	138-146	nitrate transporter 1.1	Arabidopsis thaliana	66-72
19540883-1	2009	N-Glycosylation of human beta1,3N-acetylglucosaminyltransferase 2 (beta3GnT2) is essential for its biological function.	Nitrogen	0-1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	25-65
19540883-1	2009	N-Glycosylation of human beta1,3N-acetylglucosaminyltransferase 2 (beta3GnT2) is essential for its biological function.	Nitrogen	0-1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	67-76
19540883-2	2009	beta3GnT2 fused to GFP(uv) (GFP(uv)-beta3GnT2) was produced by non-virus expression systems in stably transformed insect cells and silkworm larvae using a recombinant BmNPV bacmid, and purified for analysis of N-glycosylation.	Nitrogen	169-170	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	0-9
19566684-1	2009	Ecological studies have indicated that relative abundances of Gammaproteobacteria methanotrophs (Gamma-MOB) vs. Alphaproteobacteria methanotrophs (Alpha-MOB) in nitrogen (N) impacted soils are dictated in part by their abilities to tolerate inhibitory effects of ammonium and nitrite.	Nitrogen	161-169	sphingomyelin synthase 1	Homo sapiens	103-106
19566684-1	2009	Ecological studies have indicated that relative abundances of Gammaproteobacteria methanotrophs (Gamma-MOB) vs. Alphaproteobacteria methanotrophs (Alpha-MOB) in nitrogen (N) impacted soils are dictated in part by their abilities to tolerate inhibitory effects of ammonium and nitrite.	Nitrogen	161-169	sphingomyelin synthase 1	Homo sapiens	153-156
19645739-5	2009	We show that the CutA-AChE fusion proteins produced and secreted active, N-glycosylated molecules, while an AChE mutant lacking its secretory signal peptide did not produce any significant activity.	Nitrogen	73-74	cutA divalent cation tolerance homolog	Rattus norvegicus	17-21
19097698-8	2009	The photocatalytic activity of TiO2/N was higher than that of unmodified material and P25 under visible light irradiation.	Nitrogen	36-37	tubulin polymerization promoting protein	Homo sapiens	86-89
19372226-8	2009	Incubations with recombinant human UDP-glucuronosyltransferases (UGTs) and inhibition by the UGT1A4 and UGT1A1 substrates/inhibitors imipramine and bilirubin suggested that UGT1A4 is the major UGT isozyme catalyzing the N-glucuronidation of motesanib, with a minor contribution from UGT1A1.	Nitrogen	220-221	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	104-110
19518155-1	2009	The modified cinchona alkaloid-catalyzed direct Mannich-type reaction of N-unprotected 2-oxindoles with N-Ts-imine was developed to afford anti-3,3-disubstituted 2-oxindoles with vicinal chiral quaternary and tertiary carbon centers in yields up to 90% with excellent diastereoselectivities (anti/syn up to 95:5) and good enantioselectivies (up to 89% ee).	Nitrogen	73-74	synemin	Homo sapiens	297-300
19500399-3	2009	RESULTS: Biclustering was used to identify a set of genes that are N-responsive across a range of Nitrogen (N)-treatment backgrounds (i.e. nitrogen treatments under different growth conditions) using a meta-dataset of 76 Affymetrix ATH1 chips from 5 different laboratories.	Nitrogen	67-68	atonal bHLH transcription factor 1	Homo sapiens	232-236
19500399-3	2009	RESULTS: Biclustering was used to identify a set of genes that are N-responsive across a range of Nitrogen (N)-treatment backgrounds (i.e. nitrogen treatments under different growth conditions) using a meta-dataset of 76 Affymetrix ATH1 chips from 5 different laboratories.	Nitrogen	98-106	atonal bHLH transcription factor 1	Homo sapiens	232-236
19500399-3	2009	RESULTS: Biclustering was used to identify a set of genes that are N-responsive across a range of Nitrogen (N)-treatment backgrounds (i.e. nitrogen treatments under different growth conditions) using a meta-dataset of 76 Affymetrix ATH1 chips from 5 different laboratories.	Nitrogen	139-147	atonal bHLH transcription factor 1	Homo sapiens	232-236
19371349-2	2009	Nitrogen-containing bisphosphonates (N-BPs), such as zoledronic acid, induce the formation of a novel ATP analogue (1-adenosin-5"-yl ester 3-(3-methylbut-3-enyl) ester triphosphoric acid; ApppI), as a consequence of the inhibition of farnesyl pyrophosphate synthase and the accumulation of isopentenyl pyrophosphate (IPP).	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	234-265
19383836-4	2009	We herein provide the evidence that this genetic polymorphism has an effect on the N-linked glycosylation of ABCC11, intracellular sorting, and proteasomal degradation of the variant protein.	Nitrogen	83-84	ATP binding cassette subfamily C member 11	Homo sapiens	109-115
19454727-6	2009	We also show that the absence of PARP-1 or its pharmacological inhibition results in milder nephritis, with lower blood urea nitrogen levels, reduced necrotic lesions, and higher survival rates.	Nitrogen	125-133	poly (ADP-ribose) polymerase family, member 1	Mus musculus	33-39
19505369-1	2009	OBJECTIVES: Nitrogen-containing bisphosphonates, which are widely used to treat osteoporosis, act as inhibitors of farnesyl pyrophosphate synthase, one of the key enzymes of the mevalonate pathway, and thus may have the potential to enhance the effect of statins (inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase).	Nitrogen	12-20	3-hydroxy-3-methylglutaryl-CoA reductase	Rattus norvegicus	278-325
19261610-0	2009	N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1.	Nitrogen	0-1	integrin subunit beta 1	Homo sapiens	40-54
19261610-0	2009	N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1.	Nitrogen	0-1	integrin subunit beta 1	Homo sapiens	72-86
19261610-0	2009	N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1.	Nitrogen	153-154	integrin subunit beta 1	Homo sapiens	40-54
19261610-4	2009	In this study, the function of the N-glycans on the integrin beta1 subunit was investigated using sequential site-directed mutagenesis to remove the combined putative N-glycosylation sites.	Nitrogen	35-36	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	61-66
19261610-5	2009	Removal of the N-glycosylation sites on the I-like domain of the beta1 subunit (i.e. the Delta4-6 mutant) decreased both the level of expression and heterodimeric formation, resulting in inhibition of cell spreading.	Nitrogen	15-16	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	65-70
19261610-6	2009	Interestingly, cell spreading was observed only when the beta1 subunit possessed these three N-glycosylation sites (i.e. the S4-6 mutant).	Nitrogen	93-94	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	57-62
19261610-8	2009	Taken together, the results of the present study reveal for the first time that N-glycosylation of the I-like domain of the beta1 subunit is essential to both the heterodimer formation and biological function of the subunit.	Nitrogen	80-81	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	124-129
19261610-9	2009	Moreover, because the alpha5S3-5/beta1S4-6 mutant represents the minimal N-glycosylation required for functional expression of the beta1 subunit, it might also be useful for the study of molecular structures.	Nitrogen	73-74	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	33-38
19143999-7	2009	Increased expression of PLD epsilon also promoted root hair elongation and primary root growth under severe nitrogen deprivation.	Nitrogen	108-116	phospholipase D alpha 1	Arabidopsis thaliana	24-27
19143999-8	2009	The results suggest that PLD epsilon and PA promote organism growth and play a role in nitrogen signaling.	Nitrogen	87-95	phospholipase D alpha 1	Arabidopsis thaliana	25-28
18524423-4	2009	The two novel N(9)/N(7) 2-(6-amino-purine)-1-(1H-indole-3-yl)ethanone derivatives were characterized in an enhanced panel of 78 kinases showing the N(9) derivative to also inhibit MNK1 and IRR while the N(7) isomer was found to be specific for VEGF-R2.	Nitrogen	14-15	MAPK interacting serine/threonine kinase 1	Homo sapiens	180-184
18524423-4	2009	The two novel N(9)/N(7) 2-(6-amino-purine)-1-(1H-indole-3-yl)ethanone derivatives were characterized in an enhanced panel of 78 kinases showing the N(9) derivative to also inhibit MNK1 and IRR while the N(7) isomer was found to be specific for VEGF-R2.	Nitrogen	14-15	insulin receptor related receptor	Homo sapiens	189-192
18524423-4	2009	The two novel N(9)/N(7) 2-(6-amino-purine)-1-(1H-indole-3-yl)ethanone derivatives were characterized in an enhanced panel of 78 kinases showing the N(9) derivative to also inhibit MNK1 and IRR while the N(7) isomer was found to be specific for VEGF-R2.	Nitrogen	14-15	kinase insert domain receptor	Homo sapiens	244-251
19192249-8	2009	Together, our data show that the pattern of N-glycosylation of glycoproteins serves as a recognition signal for endocytosed galectin-4, which drives the raft-dependent apical pathway of glycoproteins in enterocyte-like HT-29 cells.	Nitrogen	44-45	galectin 4	Homo sapiens	124-134
19158400-4	2009	In the present study, we show that an intact leucine zipper motif is required for the efficient N-linked glycosylation of AC8, and that this N-linked glycosylation is important to target AC8 into lipid rafts.	Nitrogen	96-97	adenylate cyclase 8	Homo sapiens	122-125
19158400-4	2009	In the present study, we show that an intact leucine zipper motif is required for the efficient N-linked glycosylation of AC8, and that this N-linked glycosylation is important to target AC8 into lipid rafts.	Nitrogen	141-142	adenylate cyclase 8	Homo sapiens	122-125
19158400-4	2009	In the present study, we show that an intact leucine zipper motif is required for the efficient N-linked glycosylation of AC8, and that this N-linked glycosylation is important to target AC8 into lipid rafts.	Nitrogen	141-142	adenylate cyclase 8	Homo sapiens	187-190
19158400-6	2009	Mutants of AC8 that cannot be N-glycosylated are not demonstrably associated with rafts, although they can still be regulated by CCE; however, raft integrity is required for the regulation of these mutants.	Nitrogen	30-31	adenylate cyclase 8	Homo sapiens	11-14
19131501-4	2009	The opossum STC2 amino acid sequence had 78.8% homology with human STC2, and has a conserved putative N-linked glycosylation site.	Nitrogen	102-103	stanniocalcin 2	Homo sapiens	12-16
19091864-2	2009	Here, we show that the production of virus-like particles induced by viral matrix proteins of Lassa virus or Marburg virus was markedly inhibited by tetherin and that N-linked glycosylation of tetherin was dispensable for this antiviral activity.	Nitrogen	167-168	bone marrow stromal cell antigen 2	Homo sapiens	193-201
19302753-6	2009	RESULTS: The level of HMGB1 had a positive, high correlation with the abnormal changes of serum cardiac troponin I, alanine aminotransferase, aspartate aminotransferase, creatinine and blood urea nitrogen, as well as the pathologic scores of heart, lung, liver and kidney.	Nitrogen	196-204	high mobility group box 1	Rattus norvegicus	22-27
19055607-4	2009	All secreted forms of AACT were N-glycosylated, with the presence of complex glycans as observed naturally on human AACT.	Nitrogen	32-33	serpin family A member 3	Homo sapiens	22-26
19035765-4	2009	After a two-step desulfinylation process, this reaction provides a procedure for synthesizing diastereomerically pure syn-1,2-sulfanyl amines containing a chiral quaternary carbon adjacent to nitrogen.	Nitrogen	192-200	synapsin I	Homo sapiens	118-123
19032108-3	2009	Those are attributable to Ge-N dative bonding of pyridine through the lone pair electrons of its N atom, which is consistent with previous STM and theoretical studies.	Nitrogen	29-30	sulfotransferase family 1A member 3	Homo sapiens	139-142
19356114-5	2009	Reaction mapping with an array of recombinant UGT isozymes revealed that N-glucuronidation was predominantly catalyzed by the UGT1A family of enzymes.	Nitrogen	73-74	Ugt1a@	Rattus norvegicus	126-131
19744312-6	2009	RESULTS: With this approach, we identified novel targets of nitrogen-containing bisphosphonates, such as tubulin cofactor B and ASK/DBF4 (Activator of S-phase kinase).	Nitrogen	60-68	protein serine/threonine kinase activating protein DBF4	Saccharomyces cerevisiae S288C	132-136
19744312-8	2009	As nitrogen-containing bisphosphonates induce extensive DNA damage, we also document the role of DBF4 as a key player in nitrogen-containing bisphosphonate-induced cytotoxicity, thus explaining the effects on the cell-cycle.	Nitrogen	121-129	protein serine/threonine kinase activating protein DBF4	Saccharomyces cerevisiae S288C	97-101
19413687-6	2009	pyd2 and pyd3 mutants were unable to catabolize [2-(14)C]-uracil or to grow on uracil as the sole nitrogen source.	Nitrogen	98-106	pyrimidine 2	Arabidopsis thaliana	0-4
19055736-3	2008	Deoxyuridine triphosphatase (dUTPase) hydrolyzes dUTP, generating dUMP for biosynthesis of thymidine nucleotides while decreasing the availability of dUTP for misincorporation; uracil DNA glycosylase (UNG) cleaves uracil N-glycosylic bonds in DNA initiating base excision repair.	Nitrogen	185-186	deoxyuridine triphosphatase	Homo sapiens	0-27
19055736-3	2008	Deoxyuridine triphosphatase (dUTPase) hydrolyzes dUTP, generating dUMP for biosynthesis of thymidine nucleotides while decreasing the availability of dUTP for misincorporation; uracil DNA glycosylase (UNG) cleaves uracil N-glycosylic bonds in DNA initiating base excision repair.	Nitrogen	185-186	Deoxyuridine triphosphatase	Drosophila melanogaster	29-36
18708589-5	2008	Here we show that plasma N-Hcy-protein levels are significantly elevated in CBS- and MTHFR-deficient patients.	Nitrogen	25-26	methylenetetrahydrofolate reductase	Homo sapiens	85-90
18753296-4	2008	IL-18BP Tg mice were functionally and histologically protected against ischemic AKI as determined by blood urea nitrogen, serum creatinine, and acute tubular necrosis score.	Nitrogen	112-120	interleukin 18 binding protein	Mus musculus	0-7
19045266-1	2008	Ab initio calculations are performed at the multireference configuration-interaction level of theory on the diagonal spin-orbit functions for the lowest non-Rydberg states of (3)Pi(u) symmetry in molecular nitrogen.	Nitrogen	206-214	spindlin 1	Homo sapiens	117-121
18956087-0	2008	Photogeneration of metastable side-on N2 linkage isomers in [Ru(NH3)5N2]Cl2, [Ru(NH3)5N2]Br2 and [Os(NH3)5N2]Cl2.	Nitrogen	38-40	endogenous retrovirus group W member 5	Homo sapiens	72-75
18956087-0	2008	Photogeneration of metastable side-on N2 linkage isomers in [Ru(NH3)5N2]Cl2, [Ru(NH3)5N2]Br2 and [Os(NH3)5N2]Cl2.	Nitrogen	38-40	endogenous retrovirus group W member 5	Homo sapiens	109-112
18603002-7	2008	FC-L showed a distinct and unique specificity to N-acetylated sugars, particularly sialic acid and sialoproteins.	Nitrogen	49-50	ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase	Homo sapiens	12-13
18534984-0	2008	Hhat is a palmitoylacyltransferase with specificity for N-palmitoylation of Sonic Hedgehog.	Nitrogen	56-57	hedgehog acyltransferase	Homo sapiens	0-4
18723489-6	2008	To rationalize this, the hCAII-(4) adduct, obtained by cocrystallization, reveals not only the sulfamate group and the backbone of (4) interacting with the catalytic site and the associated hydrophobic pocket, respectively, but also the potential H-bonding between the N-(pyridin-3-ylmethyl) group and Nepsilon(2) of Gln(136).	Nitrogen	269-270	carbonic anhydrase 2	Homo sapiens	25-30
18646010-6	2008	siRNA targeting LGALS3, WBSCR17, PHF3, SDC2 and CTNNAL1 partially reversed the GlcNAc-induced phenotypes, suggesting a role for galectin-3/N-glycans, proteoglycans, O-glycans, and junctional cell adhesion.	Nitrogen	3-4	syndecan 2	Homo sapiens	39-43
18599462-1	2008	Golgi alpha-mannosidase II (GMII) is a key glycosyl hydrolase in the N-linked glycosylation pathway.	Nitrogen	69-70	alpha-Mannosidase class II a	Drosophila melanogaster	0-26
18599462-1	2008	Golgi alpha-mannosidase II (GMII) is a key glycosyl hydrolase in the N-linked glycosylation pathway.	Nitrogen	69-70	alpha-Mannosidase class II a	Drosophila melanogaster	28-32
21203140-2	2008	Furthermore, the conformation of the N-H bond is syn to the ortho-chloro group in the aniline ring and the C=O bond is syn to the ortho-methyl substituent in the benzoyl ring, similar to what is observed in 2-chloro-N-(2-chloro-phen-yl)benzamide and 2-methyl-N-phenyl-benzamide.	Nitrogen	37-38	synemin	Homo sapiens	49-52
18493238-3	2008	KIM-1 levels showed positive correlation with serum creatinine and blood urea nitrogen levels, and inverse correlation with estimated glomerular filtration rate.	Nitrogen	78-86	hepatitis A virus cellular receptor 1	Homo sapiens	0-5
20408681-1	2008	Lactoferrin (LF) produced from recombinant technologies can achieve almost identical amino acid sequences and three-dimensional structures to those extracted from mammals, but differences often arise in the carbohydrate chains attached through N-glycosylation, with altered sizes, structures, and chemical nature.	Nitrogen	244-245	RLF zinc finger	Rattus norvegicus	13-15
18494934-6	2008	However, as similar experiments performed in the presence of clodronate and pamidronate evidenced that this drug resistance was restricted to the nitrogen-containing bisphosphonates, we then hypothesized that this resistance could be associated with a differential expression of farnesyl diphos-phate synthase (FPPS) also observed in human osteosarcoma samples.	Nitrogen	146-154	farnesyl diphosphate synthase	Homo sapiens	279-309
18494934-6	2008	However, as similar experiments performed in the presence of clodronate and pamidronate evidenced that this drug resistance was restricted to the nitrogen-containing bisphosphonates, we then hypothesized that this resistance could be associated with a differential expression of farnesyl diphos-phate synthase (FPPS) also observed in human osteosarcoma samples.	Nitrogen	146-154	farnesyl diphosphate synthase	Homo sapiens	311-315
18253759-6	2008	Plasma C3 correlated positively with lipid parameters [triglyceride, cholesterol, LDL-C, apolipoprotein B (apoB), high-density lipoprotein cholesterol (HDL-C) and apoA1] and inversely with total protein, blood urea nitrogen, and creatinine.	Nitrogen	215-223	complement C3	Homo sapiens	7-9
18417639-4	2008	The GNC gene encodes a member of the Arabidopsis GATA transcription factor family and has been implicated in the regulation of chlorophyll biosynthesis as well as carbon and nitrogen metabolism.	Nitrogen	174-182	GATA type zinc finger transcription factor family protein	Arabidopsis thaliana	49-53
18426226-8	2008	The three-dimensional (2.3 A) structures of phenylethylhydrazine- and benzylhydrazine-inhibited MAO B show that alkylation occurs at the N(5) position on the re face of the covalent flavin with loss of the hydrazyl nitrogens.	Nitrogen	215-224	monoamine oxidase B	Homo sapiens	96-101
18483264-5	2008	Using the N-linked glycosylation inhibitor, tunicamycin, we show that expression levels of several RTKS (EGFR, ErbB2, ErbB3, and IGF-IR) are exquisitely sensitive to inhibition of N-linked glycosylation.	Nitrogen	10-11	insulin like growth factor 1 receptor	Homo sapiens	129-135
18366167-3	2008	One pathway involves concerted Wolff rearrangement and nitrogen extrusion, most likely in the syn rotomer.	Nitrogen	55-63	synemin	Homo sapiens	94-97
18245087-1	2008	The Tor1,2 protein kinases globally influence many cellular processes including nitrogen-responsive gene expression that correlates with intracellular localization of GATA transcription activators Gln3 and Gat1/Nil1.	Nitrogen	80-88	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	4-10
18063668-0	2008	The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms.	Nitrogen	53-54	KIAA0319	Homo sapiens	29-37
21591172-1	2008	Biological Nitrogen Fixation (BNF)1 is classically understood as a process restricted to the rhyzosphere and carried out by only few free-living organisms.	Nitrogen	11-19	chordin like 2	Homo sapiens	30-35
18179221-4	2008	The stereochemical outcome was rationalized by coordination of the magnesium atom to the quinuclidine nitrogen, thus directing the nucleophilic attack at the C-9 stereogenic center.	Nitrogen	102-110	complement C9	Homo sapiens	158-161
18380152-4	2008	The amino acid sequences of the extracellular domains of GPA and GPC had no significant homology to those from other mammalian species, including humans, and had O-linked and/or N-linked glycosylation sites.	Nitrogen	178-179	glycophorin C (Gerbich blood group)	Homo sapiens	65-68
18065556-10	2008	An Ataah T-DNA mutant, unable to grow on allantoin as sole nitrogen source, is rescued by the expression of StrepII-tagged variants of AtAAH and GmAAH, demonstrating that both proteins are functional in vivo.	Nitrogen	59-67	allantoate amidohydrolase	Arabidopsis thaliana	3-8
17935968-4	2008	To facilitate the electrochemical communication between the CNT layer and GOx, CNT was treated with nitrogen or oxygen plasma.	Nitrogen	100-108	hydroxyacid oxidase 1	Homo sapiens	74-77
18085777-2	2008	We have examined the synthesis of a single glycoform of monocyte chemotactic protein-3 (MCP-3), a CC-chemokine that consists of 76 amino acids and one N-glycosylation site.	Nitrogen	151-152	C-C motif chemokine ligand 7	Homo sapiens	56-86
18085777-2	2008	We have examined the synthesis of a single glycoform of monocyte chemotactic protein-3 (MCP-3), a CC-chemokine that consists of 76 amino acids and one N-glycosylation site.	Nitrogen	151-152	C-C motif chemokine ligand 7	Homo sapiens	88-93
18070108-8	2008	Further studies investigating the interaction of BMP-6 with different ectodomains of type I receptors revealed that N-glycosylation at Asn73 of BMP-6 in the wrist epitope is crucial for recognition by the activin receptor type I.	Nitrogen	116-117	activin A receptor type 1	Homo sapiens	205-228
18577465-1	2008	The fibroblast growth factor receptor 3 (FGFR3) secretory pathway includes N-linked glycosylation in the endoplasmic reticulum where a stringent quality control system ensures that only correctly folded receptor reaches the cell surface from where mature-functional FGFR3 signals upon ligand-mediated dimerization.	Nitrogen	75-76	fibroblast growth factor receptor 3	Homo sapiens	4-39
18577465-1	2008	The fibroblast growth factor receptor 3 (FGFR3) secretory pathway includes N-linked glycosylation in the endoplasmic reticulum where a stringent quality control system ensures that only correctly folded receptor reaches the cell surface from where mature-functional FGFR3 signals upon ligand-mediated dimerization.	Nitrogen	75-76	fibroblast growth factor receptor 3	Homo sapiens	41-46
18316315-3	2008	The predicted protein has a putative N-terminal signal peptide and possesses the typical domains of this enzyme family, such as a catalytic domain that is homologous to that of Bacillus macerans beta-glucanase, a putative N-glycosylation motif, and four cysteine residues in the central and C terminal regions of the ZmXTH1 protein.	Nitrogen	37-38	xyloglucan endo-transglycosylase/hydrolase	Zea mays	317-323
18681934-4	2008	A second screen using low concentrations of (15)N-labelled L-Arg in the growth media also identified AAP5 as being involved in L-Arg acquisition.	Nitrogen	48-49	amino acid permease 5	Arabidopsis thaliana	101-105
21200674-1	2007	The conformation of the N-H bond in the title compound (34DMPA), C(10)H(13)NO, is syn to the 3-methyl substituent in the aromatic ring, in contrast to the anti conformation observed with respect to the 3-chloro substituent in N-(3,4-dichloro-phen-yl)acetamide (34DCPA).	Nitrogen	24-25	synemin	Homo sapiens	82-85
17958405-10	2007	The large difference in the rates of the reverse reactions enabled inference of the branching ratio of reaction 1, k1b/(k1b + k1a), in the 2228-2905 K temperature range by CH laser absorption in experiments in a nitrogen bath.	Nitrogen	212-220	keratin 77	Homo sapiens	115-118
17958405-10	2007	The large difference in the rates of the reverse reactions enabled inference of the branching ratio of reaction 1, k1b/(k1b + k1a), in the 2228-2905 K temperature range by CH laser absorption in experiments in a nitrogen bath.	Nitrogen	212-220	keratin 77	Homo sapiens	120-123
18049247-1	2007	The Human Monitoring Laboratory (HML) has developed a method to measure the liquid nitrogen boil-off rate from the whole body counter"s single dewar as a function of time.	Nitrogen	83-91	C-type lectin domain containing 10A	Homo sapiens	33-36
17925379-3	2007	Furthermore, N-glycosidase treatment showed that both Panx1 (approximately 41-48 kD species) and Panx3 (approximately 43 kD) were glycosylated, whereas N-linked glycosylation-defective mutants exhibited a decreased ability to be transported to the cell surface.	Nitrogen	13-14	pannexin 1	Homo sapiens	54-59
17925379-3	2007	Furthermore, N-glycosidase treatment showed that both Panx1 (approximately 41-48 kD species) and Panx3 (approximately 43 kD) were glycosylated, whereas N-linked glycosylation-defective mutants exhibited a decreased ability to be transported to the cell surface.	Nitrogen	13-14	pannexin 3	Homo sapiens	97-102
17715132-3	2007	We show here that Pannexin1 forms a hexameric channel and reaches the cell surface but, unlike connexins, is N-glycosylated.	Nitrogen	109-110	pannexin 1	Homo sapiens	18-27
17715132-9	2007	We propose that N-glycosylation of Pannexin1 could be a significant mechanism for regulating the trafficking of these membrane proteins to the cell surface in different tissues.	Nitrogen	16-17	pannexin 1	Homo sapiens	35-44
17630348-1	2007	N,N,N-trimethylsphingosine chloride (TMS), a stable N-methylated synthetic sphingolipid analog, has been shown to modulate protein kinase C (PKC) activity and exert a number of important biological effects, including inhibition of tumor cell growth and metastasis, inhibition of leukocyte migration and respiratory burst, and inhibition of platelet aggregation.	Nitrogen	0-1	protein kinase C, delta	Mus musculus	141-144
17591618-3	2007	CFH is a 155-kDa glycoprotein containing nine potential N-glycosylation sites.	Nitrogen	56-57	complement factor H	Homo sapiens	0-3
17591618-5	2007	A 17.9-kDa mass decrease, observed after glycosidase treatment, indicated that N-glycosylation is the major post-translational modification of CFH.	Nitrogen	79-80	complement factor H	Homo sapiens	143-146
17611188-0	2007	Effect of using slush nitrogen (SN2) on development of microsurgically manipulated vitrified/warmed mouse embryos.	Nitrogen	22-30	solute carrier family 38, member 5	Mus musculus	32-35
17724847-0	2007	A thioredoxin of Sinorhizobium meliloti CE52G is required for melanin production and symbiotic nitrogen fixation.	Nitrogen	95-103	trxA2	Sinorhizobium meliloti	2-13
17439949-7	2007	The response of Gln3-Myc13 localization to stressful conditions can completely overwhelm its response to nitrogen source quality or inhibitor-generated disruption of the Tor1,2 signal transduction pathway.	Nitrogen	105-113	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	170-174
17382291-0	2007	Mutational analysis of the N-glycosylation sites of Duffy antigen/receptor for chemokines.	Nitrogen	27-28	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	52-89
17382291-2	2007	The polypeptide chain of DARC contains two NSS motifs at positions 16 and 27 and one NDS motif at position 33 that represent canonical sequences for efficient N-glycosylation.	Nitrogen	43-44	atypical chemokine receptor 1 (Duffy blood group)	Homo sapiens	25-29
17685230-7	2007	Pyrimidinic d(pC)n [Russian character: see text d(pT)n oligonucleotides interact with the second site of the RecA filament more effectively than with d(pA)n oligonucleotides.	Nitrogen	8-9	RAD51 recombinase	Homo sapiens	109-113
17652830-1	2007	Our previous studies, carried out using rat cDNA-expressed cytochrome P450 (CYP) isoforms, liver microsomes and specific CYP inhibitors, showed that the 1-N- and 3-N-demethylation of caffeine at a therapeutic concentration was predominantly catalyzed by CYP1A2 and CYP2C, its 7-N-demethylation was governed by P450s of the CYP2C subfamily, while its 8-hydroxylation was specifically mediated by CYP1A2.	Nitrogen	46-47	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	254-260
17652830-1	2007	Our previous studies, carried out using rat cDNA-expressed cytochrome P450 (CYP) isoforms, liver microsomes and specific CYP inhibitors, showed that the 1-N- and 3-N-demethylation of caffeine at a therapeutic concentration was predominantly catalyzed by CYP1A2 and CYP2C, its 7-N-demethylation was governed by P450s of the CYP2C subfamily, while its 8-hydroxylation was specifically mediated by CYP1A2.	Nitrogen	46-47	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	395-401
17520382-8	2007	Nitrogen negative balance of ERAS group was higher than control at 2nd day after surgery, but is lower intraoperation and at 6th day after operation (P&lt;0.05).	Nitrogen	0-8	ES cell expressed Ras	Homo sapiens	29-33
17220172-5	2007	We showed that the molecular basis of this defect in N- and O-glycosylation is caused by the disruption of the Cog1-Cog8 interaction due to truncation.	Nitrogen	53-54	component of oligomeric golgi complex 8	Homo sapiens	116-120
17053893-7	2007	At least three different bHLH domain transcription factors promote anthocyanin synthesis, and transcripts for one of these, i.e. GL3 were found to be sixfold enhanced by nitrogen deficiency in rosette leaves.	Nitrogen	170-178	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	129-132
17053893-8	2007	The MYB12 transcription factor, known to regulate flavonol synthesis, was slightly induced by nitrogen deficiency in seedlings.	Nitrogen	94-102	myb domain protein 12	Arabidopsis thaliana	4-9
17053893-10	2007	Together with MYB factors, especially PAP2, GL3 appears to be the BHLH partner for anthocyanin accumulation in response to nitrogen deficiency.	Nitrogen	123-131	basic helix-loop-helix (bHLH) DNA-binding superfamily protein	Arabidopsis thaliana	44-47
17419840-10	2007	Together, our data indicate an important role of AAP1 for efficient use of nitrogen sources present in the rhizosphere.	Nitrogen	75-83	amino acid permease 1	Arabidopsis thaliana	49-53
17341822-2	2007	Cauxin contains four putative N-glycosylation sites.	Nitrogen	30-31	carboxylesterase 5A	Homo sapiens	0-6
17197189-3	2007	The N-Troc-protected glucosamine glycosyl donor and 3"-O-unprotected lactose glycosyl acceptor were condensed in the presence of silver trifluoromethanesulfonate and methylsulfenyl bromide to provide corresponding trisaccharide with new beta-1-3 linkages in 92% yield.	Nitrogen	4-5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	237-245
17330748-5	2007	The expression of HIF1-alpha in various tissues in the rat died of nitrogen gas breathing was found in the nuclei at 0 hour and the expression level decreased gradually thereafter.	Nitrogen	67-75	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	18-28
17593728-2	2007	Experimental results demonstrate that complexation of Fe(II) by catechol- and thiol-containing organic ligands leads to formation of highly reactive species that reduce RDX (hexahydro-1,3,5-trinitro-1,3,5-triazine) and related N-heterocyclic nitramine explosive compounds to formaldehyde and inorganic nitrogen byproducts.	Nitrogen	302-310	radixin	Homo sapiens	169-172
17242517-1	2007	The three-dimensional molecular structure of human serum ceruloplasmin has been reinvestigated using X-ray synchrotron data collected at 100 K from a crystal frozen to liquid-nitrogen temperature.	Nitrogen	175-183	ceruloplasmin and hephaestin like 1	Bos taurus	57-70
17250693-16	2007	In subjects carrying the ECP 97(thr) variant, the cytotoxic activity may be disguised by N-linked glycosylation of the active site.	Nitrogen	89-90	ribonuclease A family member 3	Homo sapiens	25-28
22460750-3	2007	For nitrogen-containing bisphosphonates there is a correlation between in vitro potency of inhibition of a specific enzyme, farnesyl pyrophosphate synthase, and their antiresorptive potency in vivo.	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	124-155
17204094-9	2007	Biochemical characterization of the p200 molecule revealed a noncollagenous N-glycosylated acidic protein with an isoelectric point of approximately 5.5.	Nitrogen	76-77	AT-rich interaction domain 2	Homo sapiens	36-40
17064780-4	2007	Both [555-N] and [H(555)-N] showed better selectivity for Cu(II) than for Zn(II) and Ca(II).	Nitrogen	10-11	carbonic anhydrase 2	Homo sapiens	85-91
17425085-9	2007	When flushed with tap water, nitrogen and phosphorus were retained by the vegetated mesocosms, but leached from the non-vegetated mesocosms.	Nitrogen	29-37	nuclear RNA export factor 1	Homo sapiens	18-21
17158912-4	2006	Modifications of the large extracellular loop of UPIb, such as mutation of the N-glycosylation site or the cysteines involved in the formation of three disulfide bridges, or exchanging the large luminal loop of UPIb with that of UPIa did not affect the ability of UPIb to reach the cell surface.	Nitrogen	79-80	uroplakin 1B	Homo sapiens	49-53
17015442-1	2006	Tor1,2 control of type 2A-related phosphatase activities in Saccharomyces cerevisiae has been reported to be responsible for the regulation of Gln3 phosphorylation and intracellular localization in response to the nature of the nitrogen source available.	Nitrogen	228-236	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	0-4
17015442-2	2006	According to the model, excess nitrogen stimulates Tor1,2 to phosphorylate Tip41 and/or Tap42.	Nitrogen	31-39	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	51-55
17015442-5	2006	When Tor1,2 kinase activities are inhibited by limiting nitrogen, or rapamycin-treatment, Tap42 can no longer complex with Sit4.	Nitrogen	56-64	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	5-9
16931001-1	2006	Linear unselective CCR3 antagonist leads with IC(50) values in the 200 nM range were converted into low nM binding compounds selective at CCR3 by moving the piperidine nitrogen substituent to the carbon at the 2-position of the ring.	Nitrogen	168-176	C-C motif chemokine receptor 3	Homo sapiens	19-23
16931001-1	2006	Linear unselective CCR3 antagonist leads with IC(50) values in the 200 nM range were converted into low nM binding compounds selective at CCR3 by moving the piperidine nitrogen substituent to the carbon at the 2-position of the ring.	Nitrogen	168-176	C-C motif chemokine receptor 3	Homo sapiens	138-142
17056808-6	2006	Blood urea nitrogen concentrations in dams of both LPD groups were lower than their respective controls, confirming decreased protein intake.	Nitrogen	11-19	acyl-CoA synthetase bubblegum family member 1	Rattus norvegicus	51-54
17092076-1	2006	Two types of combined-isotopologue analysis have been performed on an extensive spectroscopic data set for ground-state N2 involving levels up to v=19, which is bound by half the well depth.	Nitrogen	120-122	immunoglobulin lambda variable 2-33 (non-functional)	Homo sapiens	146-150
17042482-4	2006	Here, glycosylation in the testis isoform (tACE) has been reduced by Asn-Gln point mutations at N-glycosylation sites, and the crystal structures of mutants having two and four intact sites have been solved to 2.0 A and 2.8 A, respectively.	Nitrogen	96-97	ADAM metallopeptidase domain 17	Homo sapiens	43-47
17044716-7	2006	An X-ray crystallographic analysis of representative Ph(2)P(E)- and Cy(2)P(E)-substituted species shows exclusively the E(syn)-(beta) configuration for the P-diphenyl substituted compounds and the Z(syn)-(beta) form for the P-dicyclohexyl derivatives, independent of the chalcogen and the nitrogen substituents.	Nitrogen	289-297	synemin	Homo sapiens	122-125
17044716-7	2006	An X-ray crystallographic analysis of representative Ph(2)P(E)- and Cy(2)P(E)-substituted species shows exclusively the E(syn)-(beta) configuration for the P-diphenyl substituted compounds and the Z(syn)-(beta) form for the P-dicyclohexyl derivatives, independent of the chalcogen and the nitrogen substituents.	Nitrogen	289-297	synemin	Homo sapiens	199-202
17051221-5	2006	Extensive contacts between IDE-N and IDE-C keep the degradation chamber of IDE inaccessible to substrates.	Nitrogen	31-32	insulin degrading enzyme	Homo sapiens	27-30
17083129-4	2006	We have found that disruption of the genes for either of the yeast 4E-BPs (Eap1p or Caf20p) leads to an inhibition of pseudohyphal growth in the resulting diploid yeast strain following nitrogen limitation.	Nitrogen	186-194	Eap1p	Saccharomyces cerevisiae S288C	75-80
16864577-11	2006	This suggests that the connection between Gln3 localization and Npr1 is indirect, arising from the influence of Npr1 on the ability of cells to utilize ammonia as a repressive nitrogen source.	Nitrogen	176-184	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	64-68
16864577-11	2006	This suggests that the connection between Gln3 localization and Npr1 is indirect, arising from the influence of Npr1 on the ability of cells to utilize ammonia as a repressive nitrogen source.	Nitrogen	176-184	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	112-116
16784820-9	2006	UFP-101 also blocked the N/OFQ-induced increase in CRF mRNA and POMC mRNA.	Nitrogen	25-26	proopiomelanocortin	Rattus norvegicus	64-68
16784820-10	2006	These results demonstrate that centrally administered N/OFQ activates the HPA axis via up-regulation of CRF and POMC mRNA and stimulation of corticosterone release in rats.	Nitrogen	54-55	proopiomelanocortin	Rattus norvegicus	112-116
16929095-8	2006	The amino-acid sequence determination of SPC-40 reveals two potential N-glycosylation sites at Asn39 and Asn345, but electron density for a glycan chain was only present at Asn39.	Nitrogen	70-71	chitinase 3 like 1	Bos taurus	41-47
16920918-4	2006	In this study, we show that combinatorial soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes with vesicle-associated membrane proteins (VAMPs), 23-kDa synaptosome-associated protein (SNAP-23), and syntaxin 4 underlie the differential mobilization of granules in human neutrophils.	Nitrogen	50-51	synaptosome associated protein 23	Homo sapiens	220-227
16920918-4	2006	In this study, we show that combinatorial soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes with vesicle-associated membrane proteins (VAMPs), 23-kDa synaptosome-associated protein (SNAP-23), and syntaxin 4 underlie the differential mobilization of granules in human neutrophils.	Nitrogen	50-51	syntaxin 4	Homo sapiens	234-244
16901144-5	2006	For these two diastereoselective processes, using the intermediates without N-protection as the substrates is essential because the corresponding N-Boc intermediates give poor diastereoselectivity.	Nitrogen	76-77	BOC cell adhesion associated, oncogene regulated	Homo sapiens	148-151
16901144-5	2006	For these two diastereoselective processes, using the intermediates without N-protection as the substrates is essential because the corresponding N-Boc intermediates give poor diastereoselectivity.	Nitrogen	146-147	BOC cell adhesion associated, oncogene regulated	Homo sapiens	148-151
16800010-1	2006	Compounds containing the C==N group, such as imines and their derivatives, may undergo syn-anti isomerization by two different routes: 1) photochemically, by out-of-plane rotation around the carbon-nitrogen double bond through a "perpendicular" form, and 2) thermally, by in-plane nitrogen inversion through a "linear" transition state.	Nitrogen	28-29	synemin	Homo sapiens	87-90
16800010-1	2006	Compounds containing the C==N group, such as imines and their derivatives, may undergo syn-anti isomerization by two different routes: 1) photochemically, by out-of-plane rotation around the carbon-nitrogen double bond through a "perpendicular" form, and 2) thermally, by in-plane nitrogen inversion through a "linear" transition state.	Nitrogen	198-206	synemin	Homo sapiens	87-90
16800010-1	2006	Compounds containing the C==N group, such as imines and their derivatives, may undergo syn-anti isomerization by two different routes: 1) photochemically, by out-of-plane rotation around the carbon-nitrogen double bond through a "perpendicular" form, and 2) thermally, by in-plane nitrogen inversion through a "linear" transition state.	Nitrogen	281-289	synemin	Homo sapiens	87-90
16720684-6	2006	Of the 10 expressed human UGTs (1A1, 1A3, 1A4, 1A6, 1A9, 2B4, 2B7, 2B15, and 2B17) studied, only hUGT2B4 and hUGT2B7 catalyzed the N-glucuronidation of FOSA.	Nitrogen	131-132	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	109-116
16720684-8	2006	These data show that rat liver UGT1.1, UGT2B1, and UGT2B12 catalyze the N-glucuronidation of FOSA, albeit at low rates, and that hUGT2B4 and hUGT2B7 catalyze the N-glucuronidation of FOSA.	Nitrogen	72-73	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	141-148
16751196-8	2006	Comparisons are made with similar studies done with human pols eta and iota; pol kappa is the most resistant to N(2)-bulk and the most quantitatively efficient of these in catalyzing dCTP incorporation opposite bulky guanine N(2)-adducts, particularly the largest (N(2)-BPG).	Nitrogen	112-116	DNA polymerase lambda	Homo sapiens	77-86
16824977-0	2006	In vivo MRI using liquid nitrogen cooled phased array coil at 3.0 T. A liquid nitrogen (LN2) cooled dual-channel array coil was designed and built for use on a 3.0-T whole-body scanner.	Nitrogen	78-86	NZ lupus nephritis 2	Mus musculus	88-91
16584812-10	2006	Thus, to some degree, the stimulatory effect of N/OFQ on consumption may arise from this peptide"s inhibitory influence on activity of anorexigenic pathways containing alpha-MSH.	Nitrogen	48-49	proopiomelanocortin	Rattus norvegicus	168-177
16762031-9	2006	From the correlation between gene expression and the phosphorylation level of PEPC, which was monitored as that of the maize PEPC expressed in transgenic rice plants, it was concluded that the short OsPPCK2 transcripts were expressed in rice leaf mesophyll cells upon nitrogen supplementation and phosphate starvation, whereas OsPPCK3 participated in the nocturnal phosphorylation of PEPC in these cells.	Nitrogen	268-276	phosphoenolpyruvate carboxylase 1	Zea mays	78-82
16650801-2	2006	Although several years ago the molecular target of the potent nitrogen-containing BPs (N-BPs) was identified as farnesyl diphosphate synthase, an enzyme in the mevalonate pathway, recent data have shed new light on the precise mechanism of inhibition and demonstrated that the acute-phase reaction, an adverse effect of N-BPs, is also caused by inhibition of this enzyme.	Nitrogen	62-70	farnesyl diphosphate synthase	Homo sapiens	112-141
16734561-0	2006	N-glycosylation of murine IFN-beta in a putative receptor-binding region.	Nitrogen	0-1	interferon beta 1, fibroblast	Mus musculus	26-34
16684881-2	2006	Because of their bone-selective pharmacokinetics, nitrogen-containing bisphosphonates (N-BPs), currently used as clinical inhibitors of bone-resorption diseases, target osteoclast farnesyl pyrophosphate synthase (FPPS) and inhibit protein prenylation.	Nitrogen	50-58	farnesyl diphosphate synthase	Homo sapiens	180-211
16684881-2	2006	Because of their bone-selective pharmacokinetics, nitrogen-containing bisphosphonates (N-BPs), currently used as clinical inhibitors of bone-resorption diseases, target osteoclast farnesyl pyrophosphate synthase (FPPS) and inhibit protein prenylation.	Nitrogen	50-58	farnesyl diphosphate synthase	Homo sapiens	213-217
16716111-10	2006	In addition, kallikrein protected against salt-induced renal injury by diminishing urinary protein and blood urea nitrogen levels.	Nitrogen	114-122	kallikrein related peptidase 4	Homo sapiens	13-23
16784711-7	2006	The scores were 1.6 +/- 0.7 at 48 h and 0.9 +/- 0.6 at 72 h in Ad-HIF-1alpha group, and there were statistical significance compared with Ad group (2.9 +/- 0.6 and 3.2 +/- 0.6 respectively) and NS group (3.0 +/- 0.7 and 3.2 +/- 0.8) (P &lt; 0.05).	Nitrogen	194-196	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	66-76
16784711-8	2006	The infarct volume was 81.2 mm(3) +/- 1.4 mm(3) at 72 h in Ad-HIF-1alpha group and there was statistical significance compared with Ad group (173.9 mm(3) +/- 1.3 mm(3)) and NS group (171.7 mm(3) +/- 6.2 mm(3)) (P &lt; 0.05).	Nitrogen	173-175	hypoxia inducible factor 1 subunit alpha	Rattus norvegicus	62-72
16754299-2	2006	As a result of heterogeneous N-glycosylation, CD147 exists in both a highly glycosylated form, HG-CD147 ( approximately 40-60 kDa) and lowly glycosylated form, LG-CD147 ( approximately 32 kDa).	Nitrogen	29-30	basigin	Mus musculus	46-51
16754299-5	2006	By treatment with tunicamycin (TM), an inhibitor of N-glycosylation, the expression level of HG-CD147 decreased and the LG-CD147 disappeared completely in HcaF cells.	Nitrogen	52-53	basigin	Mus musculus	96-101
16330492-9	2006	Lactacystin and N-benzoyloxycarbonyl (Z)-Leu-Leu-leucinal (MG132), inhibitors of proteasomal proteolysis, prevented the decrease, supporting the proteasomal degradation of p53 upon APAP exposure.	Nitrogen	16-17	tumor protein p53	Sus scrofa	172-175
16496096-3	2006	Following transfer to a medium containing allantoin as the sole nitrogen source, Ataah T-DNA insertion mutants were severely impaired and eventually died.	Nitrogen	64-72	allantoate amidohydrolase	Arabidopsis thaliana	81-86
16337118-1	2006	Exploiting the SAR of the known pyrrole derivatives, a new class of mGluR1 antagonists was developed through a cyclization of the C-2 position on the pyrrole N-1 nitrogen.	Nitrogen	162-170	sarcosine dehydrogenase	Homo sapiens	15-18
16492043-2	2006	Stereoselective synthesis of octahydro-5,6,6a-triazaacenaphthalenes 29 and 34 having the anti-relationship of the angular hydrogens flanking the pyrrolidine nitrogen confirmed suspicions that the relative configuration of the left-hand tricyclic guanidine fragment of batzelladine F should be revised to have the syn relationship of these hydrogens.	Nitrogen	157-165	synemin	Homo sapiens	16-19
16438550-0	2006	Cu-catalyzed N-arylation of oxazolidinones: an efficient synthesis of the kappa-opioid receptor Agonist CJ-15161.	Nitrogen	13-14	opioid receptor kappa 1	Homo sapiens	74-95
16469141-2	2006	We studied whether n-3 long-chain PUFA could prevent insulin resistance induced by dexamethasone (a glucocorticoid) in healthy human volunteers.	Nitrogen	19-20	pumilio RNA binding family member 3	Homo sapiens	34-38
16892359-1	2006	To understand the structural basis for bisphosphonate therapy of bone diseases, we solved the crystal structures of human farnesyl pyrophosphate synthase (FPPS) in its unliganded state, in complex with the nitrogen-containing bisphosphonate (N-BP) drugs zoledronate, pamidronate, alendronate, and ibandronate, and in the ternary complex with zoledronate and the substrate isopentenyl pyrophosphate (IPP).	Nitrogen	206-214	farnesyl diphosphate synthase	Homo sapiens	122-153
16892359-1	2006	To understand the structural basis for bisphosphonate therapy of bone diseases, we solved the crystal structures of human farnesyl pyrophosphate synthase (FPPS) in its unliganded state, in complex with the nitrogen-containing bisphosphonate (N-BP) drugs zoledronate, pamidronate, alendronate, and ibandronate, and in the ternary complex with zoledronate and the substrate isopentenyl pyrophosphate (IPP).	Nitrogen	206-214	farnesyl diphosphate synthase	Homo sapiens	155-159
16213146-5	2006	To compare the binding mode of N-trifluoroacetyl derivative with that of the lead molecule, we also determined the structure of GPb-NAG complex at a higher resolution (1.9 angstroms).	Nitrogen	31-32	glycogen phosphorylase B	Homo sapiens	128-131
16289536-3	2005	We identified a yeast gene, SFG1, whose overexpression predominantly enhances superficial pseudohyphal growth when starved for nitrogen.	Nitrogen	127-135	Sfg1p	Saccharomyces cerevisiae S288C	28-32
16105974-5	2005	The inhibitory effect of NS-187 extends to 12 of 13 Bcr-Abl proteins with mutations in their kinase domain but not to T315I.	Nitrogen	25-27	ABL proto-oncogene 1, non-receptor tyrosine kinase	Homo sapiens	52-59
15950340-5	2005	At the lowest treatment, most of the additional N was found in plant/litter compartments, but at higher treatments, there were steep increases in the amount of additional N in the underlying organic and mineral (Eag) horizons.	Nitrogen	171-172	potassium voltage-gated channel subfamily H member 1	Homo sapiens	212-215
16157583-6	2005	Finally, we have mapped the N-glycosylation sites on the beta1 integrin to better understand the potential effects of differential sialylation on integrin structure/function.	Nitrogen	28-29	integrin subunit beta 1	Homo sapiens	57-71
16262716-10	2005	These observations suggest a function for GNC in regulating carbon and nitrogen metabolism.	Nitrogen	71-79	GATA type zinc finger transcription factor family protein	Arabidopsis thaliana	42-45
16388471-4	2005	In this study, a set of experiments was performed to elucidate the effect of N nutrition on the activities of key enzymes involved in flavonoid biosynthesis (phenylalanine ammonia-lyase [PAL], chalcone synthase/chalcone isomerase [CHS/CHI}, flavanone 3-hydroxylase [FHT], flavonol synthase [FLS], dihydroflavonol 4-reductase [DFR]) and the accumulation of different groups of phenylpropanoids.	Nitrogen	77-78	naringenin,2-oxoglutarate 3-dioxygenase	Malus domestica	266-269
16388471-4	2005	In this study, a set of experiments was performed to elucidate the effect of N nutrition on the activities of key enzymes involved in flavonoid biosynthesis (phenylalanine ammonia-lyase [PAL], chalcone synthase/chalcone isomerase [CHS/CHI}, flavanone 3-hydroxylase [FHT], flavonol synthase [FLS], dihydroflavonol 4-reductase [DFR]) and the accumulation of different groups of phenylpropanoids.	Nitrogen	77-78	bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase	Malus domestica	297-324
16388471-4	2005	In this study, a set of experiments was performed to elucidate the effect of N nutrition on the activities of key enzymes involved in flavonoid biosynthesis (phenylalanine ammonia-lyase [PAL], chalcone synthase/chalcone isomerase [CHS/CHI}, flavanone 3-hydroxylase [FHT], flavonol synthase [FLS], dihydroflavonol 4-reductase [DFR]) and the accumulation of different groups of phenylpropanoids.	Nitrogen	77-78	bifunctional dihydroflavonol 4-reductase/flavanone 4-reductase	Malus domestica	326-329
16105734-0	2005	Optimization of piperazinebenzylamines with a N-(1-methoxy-2-propyl) side chain as potent and selective antagonists of the human melanocortin-4 receptor.	Nitrogen	46-47	melanocortin 4 receptor	Homo sapiens	129-152
16105734-1	2005	Piperazinebenzylamines bearing a small N-(1-methoxy-2-propyl) side chain were found to be potent and selective antagonists of the human melanocortin-4 (MC4) receptor.	Nitrogen	39-40	melanocortin 4 receptor	Homo sapiens	136-165
16216587-5	2005	A G.C+ Hoogsteen base pair suggests a specific mechanism for hPoliota"s ability to bypass N(2)-adducted guanines that obstruct replication.	Nitrogen	90-94	DNA polymerase mu	Homo sapiens	61-69
16034139-5	2005	Relative to controls, C3aRa-treated animals were protected from renal disease as measured by albuminuria (p = 0.040) and blood urea nitrogen (p = 0.021).	Nitrogen	132-140	complement component 3a receptor 1	Mus musculus	22-27
15992386-2	2005	Formation of a complex of soluble N-ethylmaleimide-sensitive fusion protein receptor (SNARE) proteins, including vesicle-associated membrane protein-2 (VAMP-2) in the synaptic vesicle membrane, and syntaxin 1 and synaptosomal-associated protein of 25 kDa (SNAP-25) in the plasma membrane, is essential for exocytosis.	Nitrogen	34-35	synaptosome associated protein 25	Rattus norvegicus	213-254
15992386-2	2005	Formation of a complex of soluble N-ethylmaleimide-sensitive fusion protein receptor (SNARE) proteins, including vesicle-associated membrane protein-2 (VAMP-2) in the synaptic vesicle membrane, and syntaxin 1 and synaptosomal-associated protein of 25 kDa (SNAP-25) in the plasma membrane, is essential for exocytosis.	Nitrogen	34-35	synaptosome associated protein 25	Rattus norvegicus	256-263
16833827-1	2005	cis-2,3-Dimethylaziridine reacts with difluoroamine to give the corresponding alkene and nitrogen with retention of configuration.	Nitrogen	89-97	suppressor of cytokine signaling 2	Homo sapiens	0-5
15901697-17	2005	Thus, AtzF affects the cleavage of three carbon-to-nitrogen bonds via a mechanism similar to that of enzymes catalyzing single-amide-bond cleavage reactions.	Nitrogen	51-59	atzF	Pseudomonas sp. ADP	6-10
15755509-9	2005	These results suggest that AK04 is a nitrogen mustard with binary bcr-abl/DNA targeting effects, a property that may account for its superior potency when compared with the classical mustard chlorambucil.	Nitrogen	37-45	ABL proto-oncogene 1, non-receptor tyrosine kinase	Homo sapiens	66-73
15882434-4	2005	Kidney damages, which were evaluated by levels of blood urea nitrogen (BUN) and creatinine, showed that MBL DKO mice were significantly protected compared with WT mice.	Nitrogen	61-69	mannose-binding lectin (protein C) 2	Mus musculus	104-107
15785817-3	2005	The 5,5-dimethyl-4-(dimethylamino)-2-ethyl-2-pyridine-4-yl-2,5-dihydro-1H-imidazol-1-oxyl showed a monotonic increase in the isotropic nitrogen hyperfine (hfi) coupling constant alpha(N) of 1 .4 G over a pH range from 2 to 6.5.	Nitrogen	135-143	mitochondrial ribosomal protein L49	Homo sapiens	178-191
15761664-1	2005	Purple acid phosphatase (PAP), also known as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase (Acp5) is synthesized as an N-glycosylated monomeric latent precursor, which can be processed by limited proteolysis to a disulfide-linked two-subunit form with increased enzyme activity.	Nitrogen	156-157	acid phosphatase 5, tartrate resistant	Rattus norvegicus	45-80
15761664-1	2005	Purple acid phosphatase (PAP), also known as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase (Acp5) is synthesized as an N-glycosylated monomeric latent precursor, which can be processed by limited proteolysis to a disulfide-linked two-subunit form with increased enzyme activity.	Nitrogen	156-157	acid phosphatase 5, tartrate resistant	Rattus norvegicus	82-86
15761664-1	2005	Purple acid phosphatase (PAP), also known as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase (Acp5) is synthesized as an N-glycosylated monomeric latent precursor, which can be processed by limited proteolysis to a disulfide-linked two-subunit form with increased enzyme activity.	Nitrogen	156-157	acid phosphatase 5, tartrate resistant	Rattus norvegicus	104-127
15761664-1	2005	Purple acid phosphatase (PAP), also known as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase (Acp5) is synthesized as an N-glycosylated monomeric latent precursor, which can be processed by limited proteolysis to a disulfide-linked two-subunit form with increased enzyme activity.	Nitrogen	156-157	acid phosphatase 5, tartrate resistant	Rattus norvegicus	129-133
15590769-11	2005	We conclude that the stable N,N(CH3)2-Dmt-Tic-NH2 compound represents a useful tool to explore the spontaneous activity of delta receptors, and NTI and novel derivatives behave as neutral antagonists.	Nitrogen	28-30	aryl hydrocarbon receptor nuclear translocator like	Homo sapiens	42-45
15755826-11	2005	CONCLUSIONS: Each intervention (dietary counseling or n-3 PUFA supplements) reduced sTM and sICAM-1 concentrations, indicating decreased endothelial activation.	Nitrogen	19-20	sulfotransferase family 1A member 3	Homo sapiens	84-87
15707601-4	2005	Mature duck PRL contains the consensus sequence for N-linked glycoslylation at position 6 which is not present in either chickens or turkeys.	Nitrogen	52-53	prolactin	Gallus gallus	12-15
15723445-6	2005	Administration of an adenovirus encoding CT-1 to NS-398-treated rats restituted normal levels of COX-1, prostaglandins, and VEGF in the liver after partial hepatectomy and restored normal liver regeneration.	Nitrogen	49-51	cardiotrophin 1	Rattus norvegicus	41-45
15545280-7	2005	High mannose glycans were absent in ICAM-1, which did not bind to the lectin, but they appeared in ICAM-1 mutants with additional N-linked glycosylation and lectin binding activity.	Nitrogen	130-131	intercellular adhesion molecule 1	Homo sapiens	99-105
15590661-1	2005	Human thyroperoxidase (hTPO), the key enzyme involved in thyroid hormone synthesis, is synthesized in the form of a 933-amino acid polypeptide that subsequently undergoes posttranslational modifications such as N- and O-glycosylation and heme fixation.	Nitrogen	211-212	thyroid peroxidase	Homo sapiens	6-21
15590661-1	2005	Human thyroperoxidase (hTPO), the key enzyme involved in thyroid hormone synthesis, is synthesized in the form of a 933-amino acid polypeptide that subsequently undergoes posttranslational modifications such as N- and O-glycosylation and heme fixation.	Nitrogen	211-212	thyroid peroxidase	Homo sapiens	23-27
15309461-4	2005	AIM: To examine the impact of dietary n-6:n-3 PUFA ratio on membrane fatty acid composition, blood lipid levels and markers of insulin sensitivity in Indian Asians living in the UK.	Nitrogen	13-14	pumilio RNA binding family member 3	Homo sapiens	46-50
15659323-7	2005	Since the hypercalcaemic effect of parathyroid hormone-related protein infusion plateaued at 20 pmol/h, and higher doses of parathyroid hormone-related protein caused an elevation of blood urea nitrogen, the parathyroid hormone-related protein infusion rate was fixed at 20 pmol/h to avoid renal dysfunction and at 40 pmol/h to elicit renal dysfunction.	Nitrogen	194-202	parathyroid hormone-like hormone	Rattus norvegicus	124-159
15659323-7	2005	Since the hypercalcaemic effect of parathyroid hormone-related protein infusion plateaued at 20 pmol/h, and higher doses of parathyroid hormone-related protein caused an elevation of blood urea nitrogen, the parathyroid hormone-related protein infusion rate was fixed at 20 pmol/h to avoid renal dysfunction and at 40 pmol/h to elicit renal dysfunction.	Nitrogen	194-202	parathyroid hormone-like hormone	Rattus norvegicus	124-159
16335806-2	2005	The results revealed that panda PRL cDNA encodes a precursor protein of 229 amino acids including a putative signal peptide of 30 amino acids and a mature protein of 199 residues with one potential N-glycosylation site.	Nitrogen	38-39	prolactin	Ailuropoda melanoleuca	32-35
15499378-7	2005	In both DU145 and PC3, IGF1R knockdown led to enhancement of sensitivity to mitoxantrone, etoposide, nitrogen mustard and ionizing radiation.	Nitrogen	101-109	insulin like growth factor 1 receptor	Homo sapiens	23-28
16200656-6	2005	Absolute reduced mobilities in nitrogen were 1.88, 1.56, 1.33, 1.15, 1.02, 0.92, 0.84, 0.73, and 0.67 cm2 V(-1) s(-1), for C2--C8, C10 and C12 tetraalkylammonium halides, respectively.	Nitrogen	31-39	chromosome 12 open reading frame 57	Homo sapiens	131-134
15634132-0	2004	A density functional study on nitrogen-doped carbon clusters CnN3- (n=1-8).	Nitrogen	30-38	calponin 3	Homo sapiens	61-65
15579431-0	2004	Minodronate, a newly developed nitrogen-containing bisphosphonate, suppresses melanoma growth and improves survival in nude mice by blocking vascular endothelial growth factor signaling.	Nitrogen	31-39	vascular endothelial growth factor A	Mus musculus	141-175
15795993-5	2004	Structure-activity relationship suggested that the nitrogen substituents at C-3 and/or C-20 of steroidal skeleton and the hydrophobic properties of the pregnane skeleton are the key structural features contributed to the inhibitory potency of these steroidal alkaloids against AChE and BChE.	Nitrogen	51-59	cholinesterase	Oryctolagus cuniculus	286-290
15497034-8	2004	In the cerebral cortex of the rat brain, the acute administration of morphine (NS-Mor) increased GRK5 protein level by about 60% while the chronic morphine treatment (Mor-Mor) increased GRK5 protein level even higher [about 130% compared with the control group (chronic saline treatment, NS-NS) group, P&lt;0.01].	Nitrogen	79-81	G protein-coupled receptor kinase 5	Rattus norvegicus	97-101
15476353-5	2004	In each complex, the copper(II) center is found in a trigonal bipyramidal (TBP) geometry consisting of four amine nitrogen atoms, with the bridgehead nitrogen in an axial position and an S-bound thiosulfate in the other axial site.	Nitrogen	114-122	TATA-box binding protein	Homo sapiens	75-78
15366019-5	2004	We show that the N-terminally nonphosphorylated form of beta-catenin as well as beta-catenin signaling is first detectable in the extraembryonic visceral endoderm in day 5.5 embryos.	Nitrogen	17-18	catenin (cadherin associated protein), beta 1	Mus musculus	56-68
15387606-4	2004	When indolylboronic acids were reacted with phenyl bromides, yields were somewhat lower and depended on the nitrogen substituent, being highest in the absence of protection, lower in the presence of the Boc group, and lowest of all with the Tos group.	Nitrogen	108-116	BOC cell adhesion associated, oncogene regulated	Homo sapiens	203-206
15514770-0	2004	Oxygen and nitrogen Lewis base adducts of [UO2(OTf)2].	Nitrogen	11-19	POU class 2 homeobox 2	Homo sapiens	47-52
15514770-5	2004	The bi- or terdentate nitrogen molecules 2,2"-bipy, phen or terpy reacted with 1 in acetonitrile or pyridine to give [UO2(OTf)2(bipy)2](7), [UO2(phen)3][OTf]2(8), [UO2(OTf)2(terpy)](9) and [UO2(terpy)2][OTf]2(10), respectively.	Nitrogen	22-30	POU class 2 homeobox 2	Homo sapiens	122-127
15514770-5	2004	The bi- or terdentate nitrogen molecules 2,2"-bipy, phen or terpy reacted with 1 in acetonitrile or pyridine to give [UO2(OTf)2(bipy)2](7), [UO2(phen)3][OTf]2(8), [UO2(OTf)2(terpy)](9) and [UO2(terpy)2][OTf]2(10), respectively.	Nitrogen	22-30	POU class 2 homeobox 2	Homo sapiens	168-173
15458348-3	2004	As a continuation of this work, here we studied the N-demethylation of CPZ by the hydroperoxidase activity of covalent immobilized soybean lipoxygenase.	Nitrogen	52-53	linoleate 9S-lipoxygenase-4	Glycine max	139-151
15458348-6	2004	The results obtained in this work, together with those obtained previously by us for the oxidation of CPZ, suggest that hydroperoxidase activity of immobilized lipoxygenase may constitute a valuable tool for oxidative xenobiotics degradation or for application to synthetic processes in which a N-demethylation reaction is involved.	Nitrogen	295-296	linoleate 9S-lipoxygenase-4	Glycine max	160-172
15250731-2	2004	By choosing the proper protective groups on imine nitrogen, either anti- or syn-beta-amino alcohol was obtained in good diastereomeric ratio, yield, and excellent enantiomeric excess using the same zinc catalysis.	Nitrogen	50-58	synemin	Homo sapiens	76-79
15245913-5	2004	Both forms of DP9 have no transmembrane domain and two potential N-linked glycosylation sites.	Nitrogen	65-66	dipeptidyl peptidase 9	Homo sapiens	14-17
15239850-1	2004	The nitrogen mustards bis(2-chloroethyl)ethylamine (HN1), bis(2-chloroethyl)methylamine (HN2), and tris(2-chloroethyl)amine (HN3) have the potential to be used as chemical terrorism agents because of their extreme vesicant properties.	Nitrogen	4-12	MT-RNR2 like 3 (pseudogene)	Homo sapiens	125-128
15199127-5	2004	To check the validity of this idea, we examined whether Poliota could incorporate nucleotides opposite the gamma-HOPdG adduct, which is formed from an initial reaction of acrolein with the N(2) of guanine.	Nitrogen	189-193	DNA polymerase mu	Homo sapiens	56-63
15183061-0	2004	N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins.	Nitrogen	0-1	C-X-C motif chemokine receptor 4	Homo sapiens	30-35
15183061-2	2004	We investigated the role of N-linked glycosylation in the N-terminus of CXCR4 in binding to HIV-1 gp120 envelope glycoproteins.	Nitrogen	28-29	C-X-C motif chemokine receptor 4	Homo sapiens	72-77
15183061-3	2004	Gp120s from CXCR4 (X4) and CCR5 (R5) using HIV-1 strains bound more efficiently to non-N-glycosylated than to N-glycosylated CXCR4 proteoliposomes in a CD4-dependent manner.	Nitrogen	87-88	C-X-C motif chemokine receptor 4	Homo sapiens	12-17
15183061-3	2004	Gp120s from CXCR4 (X4) and CCR5 (R5) using HIV-1 strains bound more efficiently to non-N-glycosylated than to N-glycosylated CXCR4 proteoliposomes in a CD4-dependent manner.	Nitrogen	110-111	C-X-C motif chemokine receptor 4	Homo sapiens	12-17
15183061-3	2004	Gp120s from CXCR4 (X4) and CCR5 (R5) using HIV-1 strains bound more efficiently to non-N-glycosylated than to N-glycosylated CXCR4 proteoliposomes in a CD4-dependent manner.	Nitrogen	110-111	C-X-C motif chemokine receptor 4	Homo sapiens	125-130
15183061-4	2004	Similar results were observed in binding studies using non-N-glycosylated or N-glycosylated CXCR4 expressed on cells.	Nitrogen	77-78	C-X-C motif chemokine receptor 4	Homo sapiens	92-97
15183061-5	2004	Mutation of the N-glycosylation site N11 in CXCR4 (N11Q-CXCR4) enhanced CD4-dependent binding of X4 and R5 gp120s and allowed more efficient entry of viruses pseudotyped with X4 or R5 HIV-1 envelope glycoproteins.	Nitrogen	16-17	C-X-C motif chemokine receptor 4	Homo sapiens	44-49
15183061-5	2004	Mutation of the N-glycosylation site N11 in CXCR4 (N11Q-CXCR4) enhanced CD4-dependent binding of X4 and R5 gp120s and allowed more efficient entry of viruses pseudotyped with X4 or R5 HIV-1 envelope glycoproteins.	Nitrogen	16-17	C-X-C motif chemokine receptor 4	Homo sapiens	56-61
15183061-8	2004	These findings demonstrate that N-glycosylation at N11 inhibits the binding of CXCR4 to X4 and R5 HIV-1 gp120, and provide a better understanding of the structural elements of CXCR4 involved in HIV-1 Env-co-receptor interactions.	Nitrogen	32-33	C-X-C motif chemokine receptor 4	Homo sapiens	79-84
15183061-8	2004	These findings demonstrate that N-glycosylation at N11 inhibits the binding of CXCR4 to X4 and R5 HIV-1 gp120, and provide a better understanding of the structural elements of CXCR4 involved in HIV-1 Env-co-receptor interactions.	Nitrogen	32-33	C-X-C motif chemokine receptor 4	Homo sapiens	176-181
15190104-8	2004	CLIC1 protein expression in microglia increases after 24 hr of incubation with Abeta, simultaneously with the production of reactive nitrogen intermediates and of tumor necrosis factor-alpha (TNF-alpha).	Nitrogen	133-141	chloride intracellular channel 1	Rattus norvegicus	0-5
15215512-9	2004	Taken together, our results suggest the existence of a GS1/AS pathway representing a metabolic route for transferring ammonium released from protein catabolism into asparagine, an amino acid that may have a major role in nitrogen mobilization from diseased tissues.	Nitrogen	221-229	asparagine synthetase	Solanum lycopersicum	59-61
15116407-9	2004	Adsorption of GM-CSF on PG-MP (PG-GMCSF) resulted in a modest increase in the surface atomic concentration of nitrogen (0.97%).	Nitrogen	110-118	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	14-20
15116407-9	2004	Adsorption of GM-CSF on PG-MP (PG-GMCSF) resulted in a modest increase in the surface atomic concentration of nitrogen (0.97%).	Nitrogen	110-118	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	34-39
15116407-10	2004	Pretreating the surface with poly-L-lysine (PG/Lys-GMCSF) prior to adding GM-CSF produced a nearly threefold increase in the surface nitrogen concentration (4.20% compared to 1.47%).	Nitrogen	133-141	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	51-56
15116407-10	2004	Pretreating the surface with poly-L-lysine (PG/Lys-GMCSF) prior to adding GM-CSF produced a nearly threefold increase in the surface nitrogen concentration (4.20% compared to 1.47%).	Nitrogen	133-141	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	74-80
15100177-0	2004	Amide N-glucuronidation of MaxiPost catalyzed by UDP-glucuronosyltransferase 2B7 in humans.	Nitrogen	6-7	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	49-80
15100177-7	2004	Of the seven human UDP-glucuronosyltransferases (UGT) isozymes (1A1, 1A3, 1A4, 1A6, 1A7, 1A10, and 2B7) tested, only UGT2B7 produced metabolite M. UGT2B7-catalyzed N-glucuronidation of BMS-204352 exhibited Michaelis-Menten kinetics with a K(m) of 14.2 microM and V(max) of 0.29 nmol/min.	Nitrogen	164-165	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	117-123
15100177-9	2004	Collectively, these results suggest that amide N-glucuronidation, a major elimination pathway of MaxiPost, is catalyzed by UGT2B7 in humans.	Nitrogen	47-48	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	123-129
15100177-10	2004	This N-glucuronide represents a fully characterized amide N-glucuronide, and glucuronidation at the nitrogen represents a newly identified conjugation reaction for UGT2B7.	Nitrogen	100-108	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	164-170
15140192-0	2004	N-linked glycosylation sites of the motor protein prestin: effects on membrane targeting and electrophysiological function.	Nitrogen	0-1	solute carrier family 26 member 5	Homo sapiens	50-57
15140192-2	2004	Prestin is a putative N-glycoprotein with three potential N-linked glycosylation sites.	Nitrogen	22-23	solute carrier family 26 member 5	Homo sapiens	0-7
15140192-5	2004	Further, treatment with tunicamycin or glycopeptidase-F was used to determine the consequences of removing N-linked glycosylation in wild-type prestin.	Nitrogen	107-108	solute carrier family 26 member 5	Homo sapiens	143-150
15140192-7	2004	Data indicate that prestin is a glycoprotein with N-linked glycosylation sites at N163 and N166.	Nitrogen	50-51	solute carrier family 26 member 5	Homo sapiens	19-26
15069543-11	2004	From the present results it is possible that reduction of N-glycosylation of the heavy chain of IgM by SW treatment may reduce anti-IgM-induced growth inhibition, and reduction in anti-IgM-induced growth inhibition due to altered N-glycosylation may enhance CD40-CD40L-mediated cell survival through TRAF2 which interacts with both IgM and CD40 in HBL-2 cells.	Nitrogen	58-59	TNF receptor associated factor 2	Homo sapiens	300-305
15116340-3	2004	We report here that the deletion of the ISW2 gene in the originally non-invasive BY strain induces mating type-specific invasive growth strongly affected by nitrogen starvation.	Nitrogen	157-165	DNA translocase	Saccharomyces cerevisiae S288C	40-44
15118319-0	2004	Inverse correlation between the nitrogen balance and induction of rat liver serine dehydratase (SDH) by dietary protein.	Nitrogen	32-40	serine dehydratase	Rattus norvegicus	76-94
15118319-0	2004	Inverse correlation between the nitrogen balance and induction of rat liver serine dehydratase (SDH) by dietary protein.	Nitrogen	32-40	serine dehydratase	Rattus norvegicus	96-99
14702339-0	2004	N-glycosylation is crucial for folding, trafficking, and stability of human tripeptidyl-peptidase I.	Nitrogen	0-1	tripeptidyl peptidase 1	Homo sapiens	76-99
14702339-3	2004	Human TPP I has five potential N-glycosylation sites at Asn residues 210, 222, 286, 313, and 443.	Nitrogen	31-32	tripeptidyl peptidase 1	Homo sapiens	6-11
14702339-5	2004	Here, we demonstrate that human TPP I in vivo utilizes all five N-glycosylation sites.	Nitrogen	64-65	tripeptidyl peptidase 1	Homo sapiens	32-37
14679193-2	2004	In Saccharomyces cerevisiae, the Tor1/2 serine/threonine kinases are global regulators situated at the top of a signal cascade reported to receive and transmit nutritional signals associated with the nitrogen supply of the cell.	Nitrogen	200-208	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	33-39
14679193-6	2004	The observations that Gln3 also accumulates in the nuclei of cells provided with poor nitrogen sources or during nitrogen starvation has led to the conclusion that Tor1/2 control intracellular Gln3 localization and NCR-sensitive transcription by regulating Gln3 phosphorylation/dephosphorylation.	Nitrogen	86-94	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	164-170
14679193-6	2004	The observations that Gln3 also accumulates in the nuclei of cells provided with poor nitrogen sources or during nitrogen starvation has led to the conclusion that Tor1/2 control intracellular Gln3 localization and NCR-sensitive transcription by regulating Gln3 phosphorylation/dephosphorylation.	Nitrogen	113-121	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	164-170
14640977-3	2004	The steady-state kinetic constants of human ETF-QO were determined with ubiquinone homologues and analogues that contained saturated n-alkyl substituents at the 6 position.	Nitrogen	19-20	electron transfer flavoprotein dehydrogenase	Homo sapiens	44-50
14978164-10	2004	Deletion of either N- or O-linked glycosylation sites abrogated IgA1 binding to TfR, suggesting that sugars are essential for IgA1 binding.	Nitrogen	19-20	immunoglobulin heavy constant alpha 1	Homo sapiens	64-68
15051866-0	2004	Effect of adding and removing N-glycosylation recognition sites on the thermostability of barley alpha-glucosidase.	Nitrogen	30-31	Agl1	Hordeum vulgare	97-114
14992719-2	2004	Regulation of such events is critical and appears to be effected by changes in CD44 N-glycosylation that switch the receptor "on" or "off" under appropriate circumstances.	Nitrogen	84-85	CD44 molecule (Indian blood group)	Homo sapiens	79-83
14992719-5	2004	Moreover, the disposition of key N-glycosylation sites reveals how specific sugar chains could alter both the affinity and avidity of CD44 HA binding.	Nitrogen	33-34	CD44 molecule (Indian blood group)	Homo sapiens	134-138
15012994-2	2004	The p38 alpha SAR is consistent with a mode of binding wherein the benzimidazolone carbonyl serves as the H-bond acceptor to Met109 of p38 alpha in a manner analogous to the pyridine nitrogen of prototypical pyridylimidazole p38 inhibitors.	Nitrogen	183-191	sarcosine dehydrogenase	Homo sapiens	14-17
14970177-0	2004	N-linked glycosylation is required for optimal function of Kaposi"s sarcoma herpesvirus-encoded, but not cellular, interleukin 6.	Nitrogen	0-1	K2	Human gammaherpesvirus 8	115-128
14967486-3	2004	To investigate the utilization of the 10 potential N-linked glycosylation sites on this E2 protein, a series of mutations consisting of single or multiple (two, three, four or eight) ablations of asparagine residues in the background of the E2(660) construct were analyzed.	Nitrogen	51-52	ubiquitin conjugating enzyme E2 B	Homo sapiens	88-98
14729345-8	2004	Amide nitrogen transverse relaxation rates for GB1 in the folded state at different temperatures exhibit large contributions from exchange processes and the associated dynamics display considerable heterogeneity.	Nitrogen	6-14	gamma-aminobutyric acid type B receptor subunit 1	Homo sapiens	47-50
14757367-5	2004	The release of TNF-alpha from SAA-stimulated neutrophils is strongly suppressed by the addition of the antioxidants N-acetyl-L-cysteine, alpha-mercaptoethanol, glutathione, the antiinflammatory dexamethasone and the compounds wortmannin (a PI3K inhibitor), PD98059 (a MEK-1 inhibitor) and SB203580 (a p38 inhibitor).	Nitrogen	16-17	serum amyloid A1 cluster	Homo sapiens	30-33
14707083-7	2004	The Thre(49)Ile polymorphism in the extracellular domain of BALB/c IL-4Ralpha has been demonstrated to disrupt N-linked glycosylation of Asn(47) and increase the dissociation rate of the IL-4Ralpha/IL-4 interaction.	Nitrogen	111-112	interleukin 4 receptor, alpha	Mus musculus	67-77
14707083-7	2004	The Thre(49)Ile polymorphism in the extracellular domain of BALB/c IL-4Ralpha has been demonstrated to disrupt N-linked glycosylation of Asn(47) and increase the dissociation rate of the IL-4Ralpha/IL-4 interaction.	Nitrogen	111-112	interleukin 4 receptor, alpha	Mus musculus	187-202
14694155-7	2004	Qualitative analysis of HSPG, using gel filtration of HNO(2)-treated fractions, showed that AngII treatment decreased N-sulfation of HS-GAG side chains.	Nitrogen	55-56	syndecan 2	Homo sapiens	24-28
14753746-0	2004	The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE).	Nitrogen	4-12	TNF superfamily member 11	Homo sapiens	68-73
14753746-0	2004	The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE).	Nitrogen	4-12	ADAM metallopeptidase domain 17	Homo sapiens	130-157
14753746-0	2004	The nitrogen-containing bisphosphonate, zoledronic acid, influences RANKL expression in human osteoblast-like cells by activating TNF-alpha converting enzyme (TACE).	Nitrogen	4-12	ADAM metallopeptidase domain 17	Homo sapiens	159-163
14753746-5	2004	MATERIALS AND METHODS: We examined the effect of the most potent nitrogen-containing BP available, zoledronic acid (ZOL), on the expression of RANKL and osteoprotegerin (OPG), critical factors in the regulation of OC formation and activation, in primary osteoblast (OB)-like cells derived from human bone, using flow cytometry, ELISA, semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR), in situ immunofluorescence staining, and Western blotting.	Nitrogen	65-73	TNF superfamily member 11	Homo sapiens	143-148
14691230-0	2004	N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding.	Nitrogen	0-1	adenosine deaminase	Homo sapiens	111-130
14561752-4	2003	Reduced cell-cell adhesion was blocked by function-blocking antibody against N-cadherin and abrogated by pre-treatment of cells with swainsonine, demonstrating the involvement of N-cadherin in the cell-cell adhesion and that changes in N-linked beta(1,6)glycan expression are responsible for the reduction in rates of adhesion, although this reduction could be mediated by the altered N-linked glycosylation of glycoproteins other than N-cadherin.	Nitrogen	77-78	cadherin 2	Mus musculus	179-189
14561752-4	2003	Reduced cell-cell adhesion was blocked by function-blocking antibody against N-cadherin and abrogated by pre-treatment of cells with swainsonine, demonstrating the involvement of N-cadherin in the cell-cell adhesion and that changes in N-linked beta(1,6)glycan expression are responsible for the reduction in rates of adhesion, although this reduction could be mediated by the altered N-linked glycosylation of glycoproteins other than N-cadherin.	Nitrogen	77-78	cadherin 2	Mus musculus	179-189
14640545-6	2003	Important roles in ligand binding are attributed to Asp162 of TM3 (interaction with a protonated nitrogen), and Thr244 of TM5 (interaction with a substituent at an aromatic moiety).	Nitrogen	97-105	tropomyosin 3	Homo sapiens	62-65
14638796-3	2003	Adherence is mediated by the cell wall surface, a domain composed essentially of mannopyranosyl residues bound to proteins, the N-linked moiety of which comprises sequences of alpha-1,2- and beta-1,2-linked mannose residues.	Nitrogen	128-129	transcriptional co-activator mating type protein alpha	Saccharomyces cerevisiae S288C	176-185
14604385-3	2003	Boc-protected amino acids were converted into alpha-amino amides; subsequent deprotection allowed the conversion into N-substituted derivatives analogously to the alpha-amino esters, without racemization in high yields under mild conditions.	Nitrogen	118-119	BOC cell adhesion associated, oncogene regulated	Homo sapiens	0-3
14576281-3	2003	The level of LKR/SDH was strongly enhanced by ABA, jasmonate, and sugar starvation, whereas excess sugars and nitrogen starvation reduced its level; thus this pathway appears to fulfill multiple functions in stress-related and carbon/nitrogen metabolism.	Nitrogen	234-242	lysine-ketoglutarate reductase/saccharopine dehydrogenase bifunctional enzyme	Arabidopsis thaliana	13-20
14730101-6	2003	This indicates inhibition by promazine of CYP1A2 (inhibition of 3-N- and 1-N-demethylation), and possibly CYP3A2 (inhibition of 8-hydroxylation), but not of other CYP isoenzymes involved in 7-N-demethylation of caffeine (e.g. CYP2B2 and/or CYP2E1).	Nitrogen	66-67	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	42-48
14499533-10	2003	The AAPBe concentrations are linearly correlated with the concentrations of suspended sediment, particulate organic carbon, particulate nitrogen, particulate phosphorus, and the AAP for several transition metals (Al, Co, Cr, Fe, Mn, Ni and Y), and the lanthanides.	Nitrogen	136-144	serpin family F member 2	Homo sapiens	4-7
12952446-6	2003	For example, addition of RN3 to MI(N2)MI results in oxidative nitrene transfer to generate [PhBPiPr3]MNR with concomitant N2 release.	Nitrogen	35-37	drosha ribonuclease III	Homo sapiens	25-28
16036064-5	2003	For nitrogen-containing bisphosphonates, the direct intracellular target is the enzyme farnesyl diphosphate synthase in the cholesterol biosynthetic pathway.	Nitrogen	4-12	farnesyl diphosphate synthase	Homo sapiens	87-116
12888520-1	2003	Regulation of CLB2 is important both for completion of the normal vegetative cell cycle in Saccharomyces cerevisiae and for departure from the vegetative cell cycle upon nitrogen deprivation.	Nitrogen	170-178	B-type cyclin CLB2	Saccharomyces cerevisiae S288C	14-18
12888520-3	2003	CLB2 transcription is regulated by additional signals, including by nitrogen levels, by positive feedback from the Clb2-Cdc28 kinase, and by osmotic stress, but the corresponding regulatory sequences and proteins have not been identified.	Nitrogen	68-76	B-type cyclin CLB2	Saccharomyces cerevisiae S288C	0-4
12799180-9	2003	Through deletion analysis we show improved sorting of DUT-N to the nucleus when most of the protein sequence is present.	Nitrogen	58-59	deoxyuridine triphosphatase	Homo sapiens	54-57
12810672-7	2003	Binding of testican 2 to N-Tes deposited on collagen allowed migration of cells expressing MT1-MMP.	Nitrogen	25-26	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2	Homo sapiens	11-21
12810672-13	2003	We propose that N-Tes-Delta 122, which is resistant to testican 2, may have therapeutic potential as a barrier against glioma invasion.	Nitrogen	16-17	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2	Homo sapiens	55-65
12796300-4	2003	Having previously shown that the Put pathway activator Put3p is differentially phosphorylated in response to the quality of the nitrogen source, we examined the phosphorylation status of Put3p after rapamycin treatment.	Nitrogen	128-136	Put3p	Saccharomyces cerevisiae S288C	55-60
12795375-4	2003	Infection of p35-expressing tobacco plants with Tobacco mosaic virus (TMV) disrupts N-mediated disease resistance, causing systemic spreading of the virus within a resistant background.	Nitrogen	84-85	interleukin 12A	Homo sapiens	13-16
12785846-0	2003	Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52.	Nitrogen	66-67	CD52 molecule	Homo sapiens	88-92
12711115-7	2003	However, tumor/normal ratio (T/N ratio) of cten/GAPDH expression was significantly higher in stage II-IV lung cancer (3.113+/-6.493) when compared with stage I lung cancer (1.237+/-1.820, P=0.0316).	Nitrogen	31-32	tensin 4	Homo sapiens	43-47
12711115-8	2003	T/N ratio of cten/GAPDH expression was significantly higher in T4 lung cancer (4.612+/-9.726) when compared with T1 lung cancer (0.896+/-0.860, P=0.0252), and T2 lung cancer (1.636+/-2.066, P=0.0470), respectively.	Nitrogen	2-3	tensin 4	Homo sapiens	13-17
12753603-0	2003	Impaired healing of nitrogen mustard wounds in CXCR2 null mice.	Nitrogen	20-28	chemokine (C-X-C motif) receptor 2	Mus musculus	47-52
12753603-6	2003	These parallel studies further establish that mice deficient in CXCR2 function exhibit delayed cutaneous wound healing that may be primarily linked to impaired neutrophil recruitment after chemical burn with nitrogen mustard.	Nitrogen	208-216	chemokine (C-X-C motif) receptor 2	Mus musculus	64-69
12753603-7	2003	Thus, there may be a potential therapeutic benefit of treating nitrogen mustard-induced skin lesions with agonists of CXCR2 to facilitate the wound repair process.	Nitrogen	63-71	chemokine (C-X-C motif) receptor 2	Mus musculus	118-123
12892045-6	2003	In all the organs studied, the activities of the enzymes involved in the anabolic nitrogen primary assimilation pathways (nitrate reductase (NR), nitrite reductase (NiR) and glutamine synthetase (GS) soared after that cadmium had been removed.	Nitrogen	82-90	glutamine synthetase	Solanum lycopersicum	174-194
12637241-18	2003	Correlation analysis suggested that CYP2B11 catalyses the N-demethylation of dextromethorphan (mediated in humans by CYP3A) and the 4"-hydroxylation of mephenytoin (mediated in humans by CYP2C19) in the dog, and that this enzyme and CYP3A12 contribute to S-warfarin 7-hydroxylation (mediated in humans by CYP2C9).	Nitrogen	58-59	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	187-194
12488460-6	2003	Digestion of immunoprecipitated TPP I proenzyme with both N-glycosidase F and endoglycosidase H as well as treatment of the cells with tunicamycin reduced the molecular mass of TPP I proenzyme by approximately 10 kDa, which indicates that all five potential N-glycosylation sites in TPP I are utilized.	Nitrogen	58-59	tripeptidyl peptidase 1	Homo sapiens	32-37
12761189-3	2003	When an N-glycosylation site was introduced at the carboxy-terminal end of b5LMY/AAA, a substantial amount of the glycosylated form of the mutant protein was recovered in the cytosol fraction.	Nitrogen	8-9	AAA1	Homo sapiens	75-84
14529538-5	2003	By contrast, the more potent, nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and zoledronate) appear to act as analogues of isoprenoid diphosphate lipids, thereby inhibiting FPP synthase, an enzyme in the mevalonate pathway.	Nitrogen	30-38	farnesyl diphosphate synthase	Homo sapiens	223-235
14529538-8	2003	Identification of FPP synthase as the target of nitrogen-containing bisphosphonates has also helped explain the molecular basis for the adverse effects of these agents in the GI tract and on the immune system.	Nitrogen	48-56	farnesyl diphosphate synthase	Homo sapiens	18-30
12619892-1	2003	Beta 1,4 galactosyltransferase 1 (beta 1,4GT1) synthesizes Gal beta 1--&gt;4GlcNAc groups in N-linked sugar chains of animal glycoproteins, which have been demonstrated to play an important role in many biological events, including sperm-egg interaction, cell migration and mammalian embryonic development.	Nitrogen	79-80	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	34-40
16228377-8	2003	Eutrophication of soils by nitrogen deposition generally favors C(3) species by offsetting the superior nitrogen use efficiency of C(4) species; this should allow C(3) species to expand at the expense of C(4) plants.	Nitrogen	27-35	complement C3	Homo sapiens	64-68
16228377-8	2003	Eutrophication of soils by nitrogen deposition generally favors C(3) species by offsetting the superior nitrogen use efficiency of C(4) species; this should allow C(3) species to expand at the expense of C(4) plants.	Nitrogen	27-35	complement C3	Homo sapiens	163-167
12536785-1	2002	The complexes TpxCu (Tpx = homoscorpionate) catalyse the insertion of diazo compounds into nitrogen-hydrogen bonds of amines and amides, under very mild conditions, with quantitative yields being obtained with equimolar ratios of reactants.	Nitrogen	91-99	thyroid peroxidase	Homo sapiens	14-17
12499404-2	2002	We introduced the human alpha-galactosidase A (alpha-GalA) gene into an S. cerevisiae mutant that was deficient in the outer chains of N-linked mannan.	Nitrogen	135-136	galactosidase alpha	Homo sapiens	24-45
12499404-2	2002	We introduced the human alpha-galactosidase A (alpha-GalA) gene into an S. cerevisiae mutant that was deficient in the outer chains of N-linked mannan.	Nitrogen	135-136	galactosidase alpha	Homo sapiens	47-57
12421952-6	2002	CL-46 has two cysteine residues in the N-terminal segment, a potential N-glycosylation site in the collagen region, and an extended hydrophilic loop close to the binding site of the carbohydrate recognition domain.	Nitrogen	39-40	collectin-46	Bos taurus	0-5
12407634-11	2002	Daily urine sulfate and urea nitrogen excretion in the sRF group were significantly less than in the HC and nRF groups.	Nitrogen	29-37	serum response factor	Homo sapiens	55-58
12408961-6	2002	Human and mouse CREG2 are N-glycosylated in HeLa cells and deletion of amino-terminal sequences completely abolishes N-glycosylation, indicating that the N termini of both proteins may function as signal sequences.	Nitrogen	26-27	cellular repressor of E1A-stimulated genes 2	Mus musculus	16-21
12055187-3	2002	Pulse-chase experiments indicate that TrkA is synthesized as a 110-kDa N-glycosylated precursor that leads to the mature 140-kDa form of the receptor with a half-life of conversion of approximately 24 +/- 0.5 min.	Nitrogen	71-72	neurotrophic receptor tyrosine kinase 1	Rattus norvegicus	38-42
12485595-0	2002	N-Glycosylation pattern of the zymogenic form of human matrix metalloproteinase-9.	Nitrogen	0-1	matrix metallopeptidase 9	Homo sapiens	55-81
12485595-4	2002	We have determined by the use of mass spectrometry that of the three possible N-glycosylation sites in human MMP-9 only two are glycosylated.	Nitrogen	78-79	matrix metallopeptidase 9	Homo sapiens	109-114
12485595-5	2002	The N-glycosylation sites are at asparagines in positions 38 and 120, the first site within the propeptide domain of the zymogenic form (pro-MMP-9) of the enzyme and the second in the catalytic domain.	Nitrogen	4-5	matrix metallopeptidase 9	Homo sapiens	141-146
12377848-5	2002	Total body protein (TBP) was measured by in vivo neutron activation analysis of nitrogen.	Nitrogen	80-88	TATA-box binding protein	Homo sapiens	0-18
12377848-5	2002	Total body protein (TBP) was measured by in vivo neutron activation analysis of nitrogen.	Nitrogen	80-88	TATA-box binding protein	Homo sapiens	20-23
12208554-7	2002	In summary, it is proposed that N-demethylation of the mentioned phenothiazine neuroleptics in the rat is catalyzed by the isoenzymes CYP2D1, CYP2B2 and CYP1A2 (CYP1A2 does not refer to promazine).	Nitrogen	32-33	cytochrome P450, family 2, subfamily d, polypeptide 1	Rattus norvegicus	134-140
12208554-7	2002	In summary, it is proposed that N-demethylation of the mentioned phenothiazine neuroleptics in the rat is catalyzed by the isoenzymes CYP2D1, CYP2B2 and CYP1A2 (CYP1A2 does not refer to promazine).	Nitrogen	32-33	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	153-159
12208554-7	2002	In summary, it is proposed that N-demethylation of the mentioned phenothiazine neuroleptics in the rat is catalyzed by the isoenzymes CYP2D1, CYP2B2 and CYP1A2 (CYP1A2 does not refer to promazine).	Nitrogen	32-33	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	161-167
12234982-6	2002	A sensitive gas chromatography high-resolution mass spectrometry assay was used to measure the major promutagenic DNA adduct, N(2),3-ethenoguanine (N(2),3-epsilonG), in rat brain and hepatocyte (HEP) DNA.	Nitrogen	126-130	heparanase	Rattus norvegicus	195-198
12093813-3	2002	In addition, immunochemical analysis of red blood cells demonstrated that hUT-B1 also exhibits ABO determinants attached to the single N-linked sugar chain at Asn-211.	Nitrogen	135-136	solute carrier family 14 member 1 (Kidd blood group)	Homo sapiens	74-80
12418581-13	2002	In the N+ patients, the mean value of CD4+/CD8+ ratio was constant, although not significantly, lower than in controls; however it progressively increased from the first to the last subinterval.	Nitrogen	7-9	CD8a molecule	Homo sapiens	43-46
12167564-7	2002	None of the UGTs examined catalyzed the N-glucuronidation of S(-)-nicotine, R(+)-nicotine, and S(-)-cotinine, including UGT1A3 and UGT1A4, the only isoforms known to catalyze many substrates at a tertiary amine.	Nitrogen	0-1	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	120-126
12354283-2	2002	The present study was designed to investigate whether the Caenorhabditis elegans fat-1 gene encoding an n-3 fatty acid desaturase (an enzyme that converts n-6 PUFAs to corresponding n-3 PUFAs) can be expressed functionally in rat cortical neurons and whether its expression can change the ratio of n-6 : n-3 fatty acids in the cell membrane and exert an effect on neuronal apoptosis.	Nitrogen	9-10	Omega-3 fatty acid desaturase fat-1	Caenorhabditis elegans	81-86
12180536-0	2002	The N-demethylation of the doxepin isomers is mainly catalyzed by the polymorphic CYP2C19.	Nitrogen	4-5	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	82-89
12180536-3	2002	RESULTS: The N-demethylation of both isomers was inhibited most prominently by tranylcypromine (CYP2C19) to more than 50%.	Nitrogen	13-14	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	96-103
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	phosphatidylinositol kinase-related protein kinase TOR1	Saccharomyces cerevisiae S288C	4-8
11923302-1	2002	The Tor1/2p signal transduction pathway regulates nitrogen catabolite repression (NCR)-sensitive (GAP1, GAT1, DAL5) and retrograde (CIT2, DLD3, IDH1/2) gene expression by controlling intracellular localization of the transcription activators, Gln3p and Gat1p, and Rtg1p and Rtg3p, respectively.	Nitrogen	50-58	Rtg1p	Saccharomyces cerevisiae S288C	264-269
12047385-9	2002	We have shown the presence of O-glycosylations, identified N-glycosylations at 11 of 15 potential sites in bovine MUC15, and a splice variant encoding a short secreted mucin.	Nitrogen	59-60	mucin 15, cell surface associated	Bos taurus	114-119
12007561-8	2002	Our data suggest that HsRad51 and Xrcc3 protein expression may be predictive of the response in B-CLL patients to treatment with nitrogen mustards.	Nitrogen	129-137	RAD51 recombinase	Homo sapiens	22-29
12007561-8	2002	Our data suggest that HsRad51 and Xrcc3 protein expression may be predictive of the response in B-CLL patients to treatment with nitrogen mustards.	Nitrogen	129-137	X-ray repair cross complementing 3	Homo sapiens	34-39
12073087-5	2002	This result suggests that Ssy1p regulates not only the transcription of amino acid permease genes, but also transcription of many other nitrogen-metabolizing genes.	Nitrogen	136-144	Ssy1p	Saccharomyces cerevisiae S288C	26-31
12073088-2	2002	The Saccharomyces cerevisae GATA-type transcription factor Ash1p is required for diploid pseudohyphal differentiation during nitrogen starvation.	Nitrogen	125-133	DNA-binding transcription repressor ASH1	Saccharomyces cerevisiae S288C	59-64
11955677-2	2002	The enzyme responsible for N-acetylation is called arylamine N-acetyltransferase (NAT),which uses acetyl coenzyme A as the acetyl group donor.	Nitrogen	27-28	bromodomain containing 2	Homo sapiens	82-85
11961028-0	2002	N-linked glycosylation is critical for the plasma membrane localization of nephrin.	Nitrogen	0-1	NPHS1 adhesion molecule, nephrin	Homo sapiens	75-82
11961028-5	2002	When cells were treated with the N-glycosylation inhibitor, tunicamycin, the molecular weight of nephrin was decreased to a single immunoband of 150 kD, indicating that the shift in the electrophoretic migration of nephrin is due to N-linked carbohydrate moieties.	Nitrogen	33-34	NPHS1 adhesion molecule, nephrin	Homo sapiens	97-104
11961028-5	2002	When cells were treated with the N-glycosylation inhibitor, tunicamycin, the molecular weight of nephrin was decreased to a single immunoband of 150 kD, indicating that the shift in the electrophoretic migration of nephrin is due to N-linked carbohydrate moieties.	Nitrogen	33-34	NPHS1 adhesion molecule, nephrin	Homo sapiens	215-222
11961028-5	2002	When cells were treated with the N-glycosylation inhibitor, tunicamycin, the molecular weight of nephrin was decreased to a single immunoband of 150 kD, indicating that the shift in the electrophoretic migration of nephrin is due to N-linked carbohydrate moieties.	Nitrogen	233-234	NPHS1 adhesion molecule, nephrin	Homo sapiens	97-104
12153019-3	2002	In this study, bacteria enriched from RDX-contaminated aquifer sediments consumed RDX in a defined, bicarbonate-buffered, anaerobic medium containing hydrogen as the sole electron donor and RDX as a potential electron acceptor and sole nitrogen source.	Nitrogen	236-244	radixin	Homo sapiens	38-41
12153019-3	2002	In this study, bacteria enriched from RDX-contaminated aquifer sediments consumed RDX in a defined, bicarbonate-buffered, anaerobic medium containing hydrogen as the sole electron donor and RDX as a potential electron acceptor and sole nitrogen source.	Nitrogen	236-244	radixin	Homo sapiens	82-85
12153019-3	2002	In this study, bacteria enriched from RDX-contaminated aquifer sediments consumed RDX in a defined, bicarbonate-buffered, anaerobic medium containing hydrogen as the sole electron donor and RDX as a potential electron acceptor and sole nitrogen source.	Nitrogen	236-244	radixin	Homo sapiens	82-85
12018850-1	2002	Liquid nitrogen (LN2) infusions are currently used in a slow controlled-rate freezing during cryopreservation.	Nitrogen	7-15	NZ lupus nephritis 2	Mus musculus	17-20
11939775-8	2002	Like Co(2+), Fe(2+) bound to yeast ferrochelatase was coordinated by approximately six oxygen or nitrogen ligands, again with evidence of two histidine ligands.	Nitrogen	97-105	ferrochelatase	Mus musculus	35-49
11973292-9	2002	Finally, we demonstrate that Spo14 phosphorylation and relocalization are initiated by nitrogen and glucose limitation and occur independently of the process of meiosis.	Nitrogen	87-95	phospholipase D	Saccharomyces cerevisiae S288C	29-34
11983124-6	2002	The expression of hepatic HGF/Met mRNA after 70% PH in BDO-PH UDCA treatment group rats was significantly increased compared with N-PH group rats (P&lt;0.05), BrdU peak labelling of hepatocytes (59.39% +/- 10.82%) in BDO-PH UDCA treatment group rats was significantly higher than that (36.22% +/- 8.37%) in BDO-PH group rats (t=4.149, P&lt;0.01) and without significance compared with N-PH group rats (68.64% +/- 11.26%, t=1.451, P &gt;0.05).	Nitrogen	36-37	hepatocyte growth factor	Rattus norvegicus	26-29
11983124-6	2002	The expression of hepatic HGF/Met mRNA after 70% PH in BDO-PH UDCA treatment group rats was significantly increased compared with N-PH group rats (P&lt;0.05), BrdU peak labelling of hepatocytes (59.39% +/- 10.82%) in BDO-PH UDCA treatment group rats was significantly higher than that (36.22% +/- 8.37%) in BDO-PH group rats (t=4.149, P&lt;0.01) and without significance compared with N-PH group rats (68.64% +/- 11.26%, t=1.451, P &gt;0.05).	Nitrogen	130-131	hepatocyte growth factor	Rattus norvegicus	26-29
11896685-9	2002	These adducts resulted from the addition of cis-2-butene-1,4-dial to the exo- and endocyclic nitrogens of 2"-deoxyadenosine and 2"-deoxyguanosine.	Nitrogen	93-102	suppressor of cytokine signaling 2	Homo sapiens	44-49
11741009-2	2002	Under hypoxic-hypoglycemic conditions, arachidonic acid release has found to be significant after 30 min, whereas c-fos expression has required at least 4 h. This model has been obtained by adding glycolytic inhibitor 2-deoxyglucose to the culture and by placing cells in an atmosphere containing 100% N2 for different time periods.	Nitrogen	302-304	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	114-119
11829764-0	2002	Effect of C-domain N-glycosylation and deletion on rat pancreatic alpha-amylase secretion and activity.	Nitrogen	19-20	amylase 2a3	Rattus norvegicus	55-79
11784148-6	2002	Test results show that a benzyl residue at the piperidine nitrogen atom and a methoxy group in position 3 are advantageous for high sigma(1)-receptor affinity.	Nitrogen	58-66	sigma non-opioid intracellular receptor 1	Rattus norvegicus	132-149
11784148-8	2002	Variation of the nitrogen substituent R from benzyl to H, alkyl, phenyl, or omega-phenylalkyl and the group X from methoxy to hydroxy, carbonyl, or alkyloxy led to reduced sigma(1)-receptor affinity.	Nitrogen	17-25	sigma non-opioid intracellular receptor 1	Rattus norvegicus	172-189
11732900-2	2001	A basic nitrogen was introduced into a general PTP inhibitor to form a salt bridge to Asp48 in PTP1B and simultaneously cause repulsion in PTPs containing an asparagine in the equivalent position [Iversen, L. F., et al.	Nitrogen	8-16	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	95-100
11717485-8	2001	Ab initio molecular orbital calculations (B3LYP/6-31+G** level) of electrostatic potentials on the molecular surface around each nitrogen confirm the experimental observations.	Nitrogen	129-137	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	44-47
12805785-2	2001	Crop production interrupts the natural balance, accelerates mineralization of N, and elevates levels of nitrate-N in soil.	Nitrogen	78-79	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	0-4
11551861-4	2001	The main adaptation was the enhancement of dietary nitrogen transferred to urea (2.2 +/- 0.5 vs. 1.3 +/- 0.1 mmol N/100 g body wt in the HP-50 and AP-50 groups, respectively).	Nitrogen	51-59	adaptor related protein complex 2 subunit mu 1	Rattus norvegicus	147-152
11590221-0	2001	N-linked glycosylation of macrophage-derived PAF-AH is a major determinant of enzyme association with plasma HDL.	Nitrogen	0-1	phospholipase A2 group VII	Homo sapiens	45-51
11519155-2	2001	Cytochrome P450(CYP) 2D6 is involved in the hydroxylation of TCAs, while N-demethylation of TCAs is mediated by other such as CYP2C19, 3A4 and 1A2.	Nitrogen	73-74	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	126-133
11320094-0	2001	Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites.	Nitrogen	141-142	ATP binding cassette subfamily A member 1	Homo sapiens	87-91
11434370-0	2001	Synthesis of C-3 nitrogen-containing derivatives of N-acetyl-alpha,beta-D-mannosamine as substrates for N-acetylneuraminic acid aldolase.	Nitrogen	17-25	complement C3	Homo sapiens	13-16
11434370-0	2001	Synthesis of C-3 nitrogen-containing derivatives of N-acetyl-alpha,beta-D-mannosamine as substrates for N-acetylneuraminic acid aldolase.	Nitrogen	17-25	N-acetylneuraminate pyruvate lyase	Homo sapiens	104-136
11434370-3	2001	A preliminary study has found that these C-3 nitrogen-substituted derivatives of ManNAc not to be substrates for Neu5Ac aldolase.	Nitrogen	45-53	complement C3	Homo sapiens	41-44
11352866-2	2001	We examined the effects of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) genotypes on the levels of N-(2-hydroxyethyl)valine (HEV) adducts in the erythrocytes and sister chromatid exchange (SCE) in lymphocytes from a group of 58 operators of sterilizers that used EtO and nonexposed workers from nine hospitals in the United States and one hospital in Mexico City.	Nitrogen	106-107	glutathione S-transferase theta 1	Homo sapiens	27-55
11352866-2	2001	We examined the effects of glutathione S-transferase T1 (GSTT1) and M1 (GSTM1) genotypes on the levels of N-(2-hydroxyethyl)valine (HEV) adducts in the erythrocytes and sister chromatid exchange (SCE) in lymphocytes from a group of 58 operators of sterilizers that used EtO and nonexposed workers from nine hospitals in the United States and one hospital in Mexico City.	Nitrogen	106-107	glutathione S-transferase theta 1	Homo sapiens	57-62
11348453-8	2001	An early intratumoral infiltration with inflammatory cells was only detected in the group that received recombinant murine granulocyte macrophage- colony-stimulating factor after necrosis induction by liquid N2.	Nitrogen	208-210	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	123-172
11328118-0	2001	Spin-polarized electrons in collisions of multicharged nitrogen ions with a magnetized Fe(001) surface.	Nitrogen	55-63	spindlin 1	Homo sapiens	0-4
11328118-1	2001	We report on the first spin-resolved energy spectra for the emission of electrons during grazing scattering of 150 keV multicharged nitrogen ions from a magnetized Fe(001) surface.	Nitrogen	132-140	spindlin 1	Homo sapiens	23-27
11282084-9	2001	A 6 h oxygen deprivation with nitrogen resulted in elevated levels of Hsp60 (media: P=0.048), of Hsp72 (intima: P&lt;0.001 and media: P=0.004) and of Hsp73 (intima: P=0.029) in the saphenous vein.	Nitrogen	30-38	heat shock protein family D (Hsp60) member 1	Homo sapiens	70-75
11282084-9	2001	A 6 h oxygen deprivation with nitrogen resulted in elevated levels of Hsp60 (media: P=0.048), of Hsp72 (intima: P&lt;0.001 and media: P=0.004) and of Hsp73 (intima: P=0.029) in the saphenous vein.	Nitrogen	30-38	heat shock protein family A (Hsp70) member 8	Homo sapiens	150-155
11264014-4	2001	Heme dissociated from the reduced cyt b(5) protein at pH approximately 3.5, whereas its rate decreased under CO atmosphere compared with N(2) atmosphere, due to formation of a heme&amp;bond;CO adduct with a histidine as an axial ligand.	Nitrogen	137-141	mitochondrially encoded cytochrome b	Homo sapiens	34-41
11098061-0	2001	Determination of the disulfide structure and N-glycosylation sites of the extracellular domain of the human signal transducer gp130.	Nitrogen	45-46	Neutrophil migration (granulocyte glycoprotein)	Homo sapiens	126-131
11512838-3	2001	The adsorptive properties and micropore structures of NiO dispersed P20 (NiO-P20) were investigated by nitrogen adsorption isotherms at 77 K. The isotherm was of type 1, suggesting that the NiO-P20 has microporosity.	Nitrogen	103-111	tubulin polymerization promoting protein family member 3	Homo sapiens	68-71
11251068-1	2001	Sed5p is the only syntaxin family member required for protein transport through the yeast Golgi and it is known to bind up to nine other soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) proteins in vivo.	Nitrogen	145-146	t-SNARE syntaxin	Saccharomyces cerevisiae S288C	0-5
11292528-4	2001	Porcine IL-18 retains the caspase-1 cleavage site present in other mammalian IL-18 proteins, but has two potential N-linked glycosylation sites not found in those proteins.	Nitrogen	115-116	interleukin 18	Homo sapiens	8-13
11292534-6	2001	The hexapeptide motif (MYPPPY), five cysteine residues, a potential N-glycosylation site and a cytoplasmic phosphatidylinositol 3-kinase binding site in canine CD28 molecule are completely conserved in canine CTLA-4.	Nitrogen	68-69	CD28 molecule	Canis lupus familiaris	160-164
11160603-2	2001	Recently, several nitrogen-containing bisphosphonates were found to inhibit osteoclast-mediated bone resorption in vitro by inhibiting farnesyl diphosphate synthase, thereby preventing protein prenylation in osteoclasts.	Nitrogen	18-26	farnesyl diphosphate synthase	Homo sapiens	135-164
11113198-5	2001	Several of the Cdc42p mutants isolated here block PH cell morphogenesis in response to nitrogen starvation without affecting morphology or polarity of yeast form cells in nutrient-rich conditions, indicating that these proteins are impaired for certain signaling functions.	Nitrogen	87-95	Rho family GTPase CDC42	Saccharomyces cerevisiae S288C	15-21
11212916-1	2001	Uptake of branched-chain amino acids by Saccharomyces cerevisiae from media containing a preferred nitrogen source is mediated by the permeases encoded by BAP2, BAP3, and VAP1/TAT1.	Nitrogen	99-107	amino acid transporter BAP3	Saccharomyces cerevisiae S288C	161-165
11212916-1	2001	Uptake of branched-chain amino acids by Saccharomyces cerevisiae from media containing a preferred nitrogen source is mediated by the permeases encoded by BAP2, BAP3, and VAP1/TAT1.	Nitrogen	99-107	amino acid transporter TAT1	Saccharomyces cerevisiae S288C	171-175
11212916-1	2001	Uptake of branched-chain amino acids by Saccharomyces cerevisiae from media containing a preferred nitrogen source is mediated by the permeases encoded by BAP2, BAP3, and VAP1/TAT1.	Nitrogen	99-107	amino acid transporter TAT1	Saccharomyces cerevisiae S288C	176-180
12889515-3	2001	The enzyme responsible for N-acetylation is called NAT.	Nitrogen	27-28	bromodomain containing 2	Homo sapiens	51-54
11102564-13	2000	We have reported several new cytotoxic agents with nitrogen atoms at C-7 or C-9 or at both C-7 and C-9: imine derivatives, oxime derivatives, pyrazoline-, pyrazo- and isoxazoline-fused cyclolignans.	Nitrogen	51-59	complement C7	Homo sapiens	69-72
11102564-13	2000	We have reported several new cytotoxic agents with nitrogen atoms at C-7 or C-9 or at both C-7 and C-9: imine derivatives, oxime derivatives, pyrazoline-, pyrazo- and isoxazoline-fused cyclolignans.	Nitrogen	51-59	complement C9	Homo sapiens	76-79
11073899-1	2000	Nitrogen-catabolic gene expression in Saccharomyces cerevisiae is regulated by the action of four GATA family transcription factors: Gln3p and Gat1p/Nil1p are transcriptional activators, and Dal80 and Deh1p/Gzf3p are repressors.	Nitrogen	0-8	Dal80p	Saccharomyces cerevisiae S288C	191-196
11191884-10	2000	Since an asparagine is conserved at the equivalent position to N61 of FMO3 in mammalian, yeast and Caenorhabditis elegans FMOs, the characterization of the naturally occurring N61S (A to G) mutation may have identified this asparagine as playing a critical role specifically in FMO-catalysed N-oxidation.	Nitrogen	63-64	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	70-74
11069679-0	2000	In vivo N-glycosylation of the mep2 high-affinity ammonium transporter of Saccharomyces cerevisiae reveals an extracytosolic N-terminus.	Nitrogen	8-9	ammonium permease MEP2	Saccharomyces cerevisiae S288C	31-35
11069679-7	2000	Site-directed mutagenesis of the four potential N-glycosylation sites of Mep2 shows that Asn-4 of the protein"s N-terminal tail is the only site that binds oligosaccharides.	Nitrogen	48-49	ammonium permease MEP2	Saccharomyces cerevisiae S288C	73-77
11090219-4	2000	When a Golgi-targeted and N-glycosylated variant of GFP was coexpressed with AtRab1b(N121I), the variant also accumulated in a reticulate network and an endoglycosidase H-sensitive population appeared.	Nitrogen	26-27	RAS 5	Arabidopsis thaliana	77-84
11015229-3	2000	Further, similar conclusions are reached when the ESR spectra of the N-acyl PE spin-labels in dimyristoylphosphatidylcholine (DMPC) or dimyristoylphosphatidylethanolamine (DMPE) host matrixes are compared with those of phosphatidylcholine spin-labels in these two lipids.	Nitrogen	69-70	spindlin 1	Homo sapiens	79-83
11079555-8	2000	In addition, quantitative removal of N-linked sugars greatly facilitated the detection of heavily glycosylated proteins and enabled sequencing by nanoelectrospray-tandem mass spectrometry as illustrated for the GPI-anchored protein, Thy-1.	Nitrogen	37-38	thy-1 membrane glycoprotein	Mesocricetus auratus	233-238
10889209-3	2000	Both GIRK1 and GIRK4 have one extracellular consensus N-glycosylation site.	Nitrogen	54-55	potassium inwardly rectifying channel subfamily J member 5	Homo sapiens	15-20
10973597-3	2000	Intracerebroventricular administration of N/OFQ induces changes in c-Fos immunoreactivity in several feeding-related brain sites.	Nitrogen	42-43	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	67-72
10973597-6	2000	We also evaluated c-Fos immunoreactivity in those areas of the brain which have been shown to exhibit altered c-Fos expression upon N/OFQ administration.	Nitrogen	132-133	Fos proto-oncogene, AP-1 transcription factor subunit	Rattus norvegicus	110-115
10965907-15	2000	In summary, overall high amino acid identity (79%), the locations of cysteine residues, and consensus sites for N-linked glycosylation between mouse and rat PLP-Cbeta clearly indicate that PLP-Cbeta is a bona fide member of the PLP-C subfamily.	Nitrogen	112-113	prolactin family 8, subfamily A, member 9	Rattus norvegicus	189-198
10937714-0	2000	N-acylated alpha-(3-pyridylmethyl)-beta-aminotetralin antagoinists of the human neuropeptide Y Y5 receptor.	Nitrogen	0-1	neuropeptide Y receptor Y5	Homo sapiens	95-106
10906059-2	2000	The encoded proteins of the two novel clones, designated prolactin-like proteins L (PLP-L) and M (PLP-M), are predicted to be synthesized as precursors of 229 and 227 amino acids, modified by N-linked glycosylation, and secreted as mature glycoproteins of 199 and 200 residues, respectively.	Nitrogen	192-193	prolactin family 5, subfamily A, member 1	Rattus norvegicus	57-82
10906059-2	2000	The encoded proteins of the two novel clones, designated prolactin-like proteins L (PLP-L) and M (PLP-M), are predicted to be synthesized as precursors of 229 and 227 amino acids, modified by N-linked glycosylation, and secreted as mature glycoproteins of 199 and 200 residues, respectively.	Nitrogen	192-193	prolactin family 5, subfamily A, member 1	Rattus norvegicus	84-89
10913840-3	2000	The two potential N-glycosylation sites of rFuc-TIV were mutated to determine site occupancy and the effect of site occupancy on enzyme activity and targeting of this enzyme.	Nitrogen	18-19	fucosyltransferase 4	Rattus norvegicus	43-51
10850990-4	2000	Put3p controls the expression of the proline utilization pathway that allows yeast cells to grow on proline as the sole nitrogen source.	Nitrogen	120-128	Put3p	Saccharomyces cerevisiae S288C	0-5
10807976-5	2000	Results showed that PDGF-B expression was not influenced by n-LDL, but was moderately increased by ox-LDL and n-Lp(a).	Nitrogen	36-37	platelet derived growth factor subunit B	Homo sapiens	20-26
10841792-3	2000	Stabilization of lead compounds against cathepsin B cleavage by N-methylation of noncritical backbone NH groups or by dipeptide mimetic substitutions has generated analogues that compete effectively against protein antigens in cellular assays, resulting in inhibition of T-cell proliferation.	Nitrogen	64-65	cathepsin B	Homo sapiens	40-51
10828967-1	2000	The receptor for parathyroid hormone (PTH) and PTH-related peptide (PTHrP) is a G-protein-coupled receptor with four potential sites for N-linked glycosylation.	Nitrogen	137-138	parathyroid hormone-like hormone	Rattus norvegicus	47-66
10828967-1	2000	The receptor for parathyroid hormone (PTH) and PTH-related peptide (PTHrP) is a G-protein-coupled receptor with four potential sites for N-linked glycosylation.	Nitrogen	137-138	parathyroid hormone-like hormone	Rattus norvegicus	68-73
10828967-4	2000	The results revealed that all four potential N-glycosylation sites in the PTH/PTHrP receptor are glycosylated.	Nitrogen	45-46	parathyroid hormone-like hormone	Rattus norvegicus	78-83
10828967-7	2000	These data indicate important roles for N-linked glycosylation in PTH/PTHrP receptor functions.	Nitrogen	40-41	parathyroid hormone-like hormone	Rattus norvegicus	70-75
15263147-2	2000	The directions of the two N-Me bond axes are syn to the Cu-Cl bond.	Nitrogen	26-27	synemin	Homo sapiens	45-48
10865769-3	2000	Direct measurements of total body nitrogen (TBN) monitor the integrated changes in TBP over time and allow comparison with normal subjects.	Nitrogen	34-42	TATA-box binding protein	Homo sapiens	83-86
10905635-0	2000	GM1 synthase depends on N-glycosylation for enzyme activity and trafficking to the Golgi complex.	Nitrogen	24-25	coenzyme Q10A	Mus musculus	0-3
10905635-2	2000	Here we examined the occupancy and relevance for the activity and intracellular trafficking of the only potential N-glycosylation site of the mouse beta1,3galactosyltransferase (Gal-T2 or GA1/GM1/GD1b synthase) in Gal-T2 cDNA transfected CHO-K1 cells.	Nitrogen	114-115	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4	Mus musculus	178-184
10905635-7	2000	Taken together, these results indicate that Gal-T2 depends on N-glycosylation for its activity and for proper trafficking to, but not its retention in, the Golgi complex.	Nitrogen	62-63	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4	Mus musculus	44-50
10777545-11	2000	Our findings suggest that N-terminal phosphorylation of ATF2 dimers protect ATF2 from ubiquitination and degradation.	Nitrogen	26-27	activating transcription factor 2	Homo sapiens	56-60
10777545-11	2000	Our findings suggest that N-terminal phosphorylation of ATF2 dimers protect ATF2 from ubiquitination and degradation.	Nitrogen	26-27	activating transcription factor 2	Homo sapiens	76-80
10773169-4	2000	A plot of g(xx) versus A(zz) of the nitrogen discloses grouping of 12 spin labeled sites in protic and aprotic sites.	Nitrogen	36-44	spindlin 1	Homo sapiens	70-74
10784435-4	2000	Bisphenol A (1 mM) most efficiently inhibited aminopyrine N-demethylation by CYP2C8 and CYP2C19 by 82% and 85%, respectively, whereas inhibition of the activities by CYP 2B6 and 2D6 was less than 40%.	Nitrogen	58-59	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	88-95
11201795-4	2000	Pretreatment of this stable clones with tunicamycin, a potent inhibitor of N-glycosylation, caused the appearance of unglycosylated Trk core protein.	Nitrogen	75-76	neurotrophic receptor tyrosine kinase 1	Rattus norvegicus	132-135
10715549-0	2000	Additional N-glycosylation at Asn(13) rescues the human LHbeta-subunit from disulfide-linked aggregation.	Nitrogen	11-12	luteinizing hormone subunit beta	Homo sapiens	56-62
10715549-7	2000	Both CGbeta wild-type (WT) and CGbeta lacking N-glycosylation at Asn(13) (CGbeta-N13) showed aggregates in lysate.	Nitrogen	46-47	chorionic gonadotropin subunit beta 3	Homo sapiens	5-11
10715549-7	2000	Both CGbeta wild-type (WT) and CGbeta lacking N-glycosylation at Asn(13) (CGbeta-N13) showed aggregates in lysate.	Nitrogen	46-47	chorionic gonadotropin subunit beta 3	Homo sapiens	31-37
10715549-7	2000	Both CGbeta wild-type (WT) and CGbeta lacking N-glycosylation at Asn(13) (CGbeta-N13) showed aggregates in lysate.	Nitrogen	46-47	chorionic gonadotropin subunit beta 3	Homo sapiens	31-37
10715549-9	2000	These results indicate that the backbone structure consisting of 114 amino acids and N-linked glycosylation at Asn(30) is involved in the aggregation of LHbeta.	Nitrogen	85-86	luteinizing hormone subunit beta	Homo sapiens	153-159
10715549-10	2000	Moreover, N-glycosylation at Asn(13) does not prevent such aggregation, but instead plays an important role in correct folding for both LHbeta- and CGbeta-subunits to be secreted as monomer.	Nitrogen	10-11	luteinizing hormone subunit beta	Homo sapiens	136-142
10715549-10	2000	Moreover, N-glycosylation at Asn(13) does not prevent such aggregation, but instead plays an important role in correct folding for both LHbeta- and CGbeta-subunits to be secreted as monomer.	Nitrogen	10-11	chorionic gonadotropin subunit beta 3	Homo sapiens	148-154
10888037-0	2000	Inhibition of N-linked glycosylation down-regulates insulin-like growth factor-1 receptor at the cell surface and kills Ewing"s sarcoma cells: therapeutic implications.	Nitrogen	14-15	insulin like growth factor 1 receptor	Homo sapiens	52-89
10888037-2	2000	We have previously demonstrated that an adequate N-linked glycosylation of IGF-1R is required for its translocation to the cell surface in melanoma cells.	Nitrogen	49-50	insulin like growth factor 1 receptor	Homo sapiens	75-81
10888037-4	2000	In this study we show that inhibition of N-linked glycosylation using tunicamycin or the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor lovastatin resulted in down-regulation of IGF-1R at the cell surface in Ewing"s sarcoma cell lines (RD-ES and ES-1 cells).	Nitrogen	41-42	insulin like growth factor 1 receptor	Homo sapiens	199-205
10640514-9	2000	In vitro analysis of wild-type and variant human FMO3 proteins expressed from the cDNA for the two naturally occurring polymorphisms showed differences in substrate affinities for nitrogen-containing substrates.	Nitrogen	180-188	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	49-53
10640514-10	2000	Thus, for polymorphic forms of human FMO3, lower k(cat)/K(m) values for N-oxygenation of 10-(N, N-dimethylaminopentyl)-2-(trifluoromethyl) phenothiazine, trimethylamine, and tyramine were observed.	Nitrogen	72-73	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	37-41
10655058-3	2000	It encodes otogelin, an N-glycosylated protein that is present in the acellular membranes covering the six sensory epithelial patches of the inner ear: in the cochlea (the auditory sensory organ), the tectorial membrane (TM) over the organ of Corti; and in the vestibule (the balance sensory organ), the otoconial membranes over the utricular and saccular maculae as well as the cupulae over the cristae ampullares of the three semi-circular canals.	Nitrogen	24-25	otogelin	Mus musculus	11-19
11015576-0	2000	A novel mutation in FGFR-3 disrupts a putative N-glycosylation site and results in hypochondroplasia.	Nitrogen	47-48	fibroblast growth factor receptor 3	Homo sapiens	20-26
10617973-6	2000	These findings also may help to explain the apparent inconsistencies in earlier studies of long-chain n-3 PUFA intake and ischemic heart disease.	Nitrogen	8-9	pumilio RNA binding family member 3	Homo sapiens	106-110
10585852-0	1999	Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells.	Nitrogen	17-18	tyrosinase-related protein 1	Mus musculus	51-79
10586085-6	1999	Treatment of fully recovered rats with l -NMA 24 h before a rechallenge with MBP-CFA leads to decreased serum reactive nitrogen intermediate levels and results in a second episode of EAE in 100% of animals.	Nitrogen	119-127	myelin basic protein	Rattus norvegicus	77-80
10525295-8	1999	Chloronucleotides formed by reaction of ClO(-) with inosine, GMP, TMP, or UMP are capable of quantitative chlorine transfer to cyclopeptides; however, no chlorine transfer between the amide nitrogen and primary amines is detectable, in either direction.	Nitrogen	190-198	5'-nucleotidase, cytosolic II	Homo sapiens	61-64
10527944-7	1999	A partly occupied N-linked glycosylation site was characterized in human SP-D.	Nitrogen	18-19	surfactant protein D	Homo sapiens	73-77
10560726-2	1999	In the SAR study, the aryl substituents on the piperazine nitrogen were found to play an important role for the anti-HIV-1 activity.	Nitrogen	58-66	sarcosine dehydrogenase	Homo sapiens	7-10
11671189-13	1999	At 260 K, both the Fe1 and Fe2 sites are high-spin (HS) with Fe-N bond lengths of 2.161(3) and 2.164(3) A, respectively.	Nitrogen	64-65	spindlin 1	Homo sapiens	46-50
10464027-1	1999	A novel series of N-(phenylalkyl)cinnamides related to N-(4-phenylbutyl)-3,4-dihydroxy-beta-cyanocinnamide (6, an EGFR-K inhibitor with high antiproliferative activity) was synthesized and tested for antagonism at N-methyl-D-aspartate (NMDA) receptor subtypes.	Nitrogen	18-19	epidermal growth factor receptor	Rattus norvegicus	114-118
10526406-0	1999	NMR exchange broadening arising from specific low affinity protein self-association: analysis of nitrogen-15 nuclear relaxation for rat CD2 domain 1.	Nitrogen	97-105	Cd2 molecule	Rattus norvegicus	136-139
10526406-2	1999	Nitrogen-15 NMR relaxation parameters have been recorded for the N-terminal domain of the rat T-cell antigen CD2 (CD2d1) in a dilution series from 1.20 mM to 40 microM (pH 6.0, 25 degrees C).	Nitrogen	0-8	Cd2 molecule	Rattus norvegicus	109-112
10526406-2	1999	Nitrogen-15 NMR relaxation parameters have been recorded for the N-terminal domain of the rat T-cell antigen CD2 (CD2d1) in a dilution series from 1.20 mM to 40 microM (pH 6.0, 25 degrees C).	Nitrogen	0-8	Cd2 molecule	Rattus norvegicus	114-119
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	Dal80p	Saccharomyces cerevisiae S288C	73-78
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	metallo-aminopeptidase	Saccharomyces cerevisiae S288C	121-125
10554772-8	1999	Another group of genes whose expression is also regulated by Gln3, Gat1, Dal80, and Deh1 are some proteases, CPS1, PRB1, LAP1, and PEP4, responsible for the degradation of proteins into amino acids thereby providing a nitrogen source to the cell.	Nitrogen	218-226	proteinase A	Saccharomyces cerevisiae S288C	131-135
10409709-0	1999	YND1, a homologue of GDA1, encodes membrane-bound apyrase required for Golgi N- and O-glycosylation in Saccharomyces cerevisiae.	Nitrogen	1-2	apyrase	Saccharomyces cerevisiae S288C	50-57
10398706-0	1999	Simultaneous expression of NAD-dependent isocitrate dehydrogenase and other krebs cycle genes after nitrate resupply to short-term nitrogen-starved tobacco Mitochondrial NAD-dependent (IDH) and cytosolic NADP-dependent isocitrate dehydrogenases have been considered as candidates for the production of 2-oxoglutarate required by the glutamine synthetase/glutamate synthase cycle.	Nitrogen	131-139	isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial	Nicotiana tabacum	27-65
10387077-6	1999	The putative binding site for cTnI(33-80) was determined by mapping amide proton and nitrogen chemical shift changes, induced by the binding of cTnI(33-80), onto the C-terminal cTnC structure.	Nitrogen	85-93	troponin I3, cardiac type	Homo sapiens	144-148
10385230-6	1999	Removal of one or both of the methyl groups from the non-isothiourea nitrogen of dimaprit improved nNOS inhibitory properties.	Nitrogen	69-77	nitric oxide synthase 1	Rattus norvegicus	99-103
10198439-5	1999	Specifically, the response to nitrogen limitation is dependent upon the presence of a functional OPI1 gene product, it requires ongoing phosphatidylcholine biosynthesis and it is mediated by the repeated element, UASINO, found in the promoter of INO1 and other co-regulated genes of phospholipid biosynthesis.	Nitrogen	30-38	transcriptional regulator OPI1	Saccharomyces cerevisiae S288C	97-101
10227578-1	1999	Nitrogen mustard (bis(2-chloroethyl) methylamine, HN2) inhibited the binding of upstream factors Sp1 and AP2 to their consensus sequences.	Nitrogen	0-8	transcription factor AP-2 alpha	Homo sapiens	105-108
10067849-5	1999	Recombinant GDF-9 was shown to be an N-glycosylated protein capable of stimulating early follicle development.	Nitrogen	37-38	growth differentiation factor 9	Rattus norvegicus	12-17
10024662-0	1999	The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation.	Nitrogen	150-151	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	29-33
10024662-9	1999	We propose that inefficient N -glycosylation of secretory proteins in cwh8 Delta cells is caused by an insufficient supply of dolichol-linked oligosaccharide substrate.	Nitrogen	28-29	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	70-74
10231086-7	1999	The two N-linked glycosylation sites in IgA1 are not required for its binding to the polymeric Ig receptor (pIgR).	Nitrogen	8-9	immunoglobulin heavy constant alpha 1	Homo sapiens	40-44
10027866-8	1999	For methamphetamine, the data were consistent with a mechanism of human FMO3-mediated N,N-dioxygenation but the immediate product, a nitrone, rapidly hydrolyzed to phenylpropanone.	Nitrogen	86-87	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	72-76
10027866-8	1999	For methamphetamine, the data were consistent with a mechanism of human FMO3-mediated N,N-dioxygenation but the immediate product, a nitrone, rapidly hydrolyzed to phenylpropanone.	Nitrogen	88-89	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	72-76
10027866-12	1999	Because of the potential toxic nature of amphetamine hydroxylamine and methamphetamine hydroxylamine metabolites and the polymorphic nature of N-oxygenation, human FMO3-mediated metabolism of amphetamine or methamphetamine may have clinical consequences.	Nitrogen	143-144	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	164-168
10049736-0	1999	Nitrogen-containing bisphosphonates inhibit isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo.	Nitrogen	0-8	farnesyl diphosphate synthase	Homo sapiens	80-111
10049736-5	1999	We found that all N-containing bisphosphonates inhibited isopentenyl pyrophosphate isomerase/farnesyl pyrophosphate synthase activity dose dependently with relative potencies corresponding to their antiresorptive potencies in vitro and in vivo, whereas clodronate and NH2-olpadronate had no effect.	Nitrogen	18-19	farnesyl diphosphate synthase	Homo sapiens	93-124
10092169-3	1999	In the case of the multigene family for glutamine synthetase, the key enzyme of nitrogen assimilation, six different cDNA sequences were isolated from leaf and root specific libraries.	Nitrogen	80-88	glutamine synthetase, chloroplastic	Brassica napus	40-60
9852126-1	1998	The human calcium receptor (hCaR) is a G-protein-coupled receptor containing 11 potential N-linked glycosylation sites in the large extracellular domain.	Nitrogen	90-91	CXADR Ig-like cell adhesion molecule	Homo sapiens	28-32
9852126-9	1998	Our results demonstrate that among 11 potential N-linked glycosylation sites on the hCaR, eight sites are actually utilized; glycosylation of at least three sites is critical for cell surface expression of the receptor, but glycosylation does not appear to be critical for signal transduction.	Nitrogen	48-49	CXADR Ig-like cell adhesion molecule	Homo sapiens	84-88
9872320-8	1998	We also show that N-glycosylation of asparagine residues blocks AEP action in vitro.	Nitrogen	18-19	legumain	Homo sapiens	64-67
9872320-9	1998	This indicates that N-glycosylation could eliminate sites of processing by AEP in mammalian proteins, allowing preferential processing of microbial antigens.	Nitrogen	20-21	legumain	Homo sapiens	75-78
9832522-2	1998	Recognition of nitrogen starvation is mediated, at least in part, by the ammonium permease Mep2p and the Galpha subunit Gpa2p.	Nitrogen	15-23	ammonium permease MEP2	Saccharomyces cerevisiae S288C	91-96
9820205-9	1998	The total translation of rZP3 peptide has a molecular weight of 45,820, containing six potential N-glycosylation sites and 75 Ser/Thr residues, possible O-glycosylation sites.	Nitrogen	97-98	zona pellucida glycoprotein 3	Rattus norvegicus	25-29
11672369-6	1998	The anti/syn selectivity can be explained by assuming transition state geometries where the delivery of the nitrogen nucleophile is controlled by lithium "chelation" between reagent and substrate.	Nitrogen	108-116	synemin	Homo sapiens	9-12
9851685-6	1998	In addition, guinea pig IL-2 has a possible N-linked glycosylation site as seen in bovine and porcine IL-2.	Nitrogen	44-45	interleukin-2	Cavia porcellus	24-28
9851685-6	1998	In addition, guinea pig IL-2 has a possible N-linked glycosylation site as seen in bovine and porcine IL-2.	Nitrogen	44-45	interleukin 2	Bos taurus	102-106
9930349-1	1998	Under physiological salt concentration, plasmid DNA complexed with transferrin-conjugated or unmodified polyethylenimine (PEI, 800 kDa) forms huge (up to &gt; 1000 nm) aggregates, unless the individual components are mixed at a highly positive nitrogen/phosphate (N/P) charge ratio.	Nitrogen	244-252	transferrin	Mus musculus	67-78
9835451-2	1998	Inhibition of N-linked glycosylation by tunicamycin, which has previously been shown to block the translocation of IGF-1R to the cell surface, blocked cell growth and/or induced cell death in these cell lines.	Nitrogen	14-15	insulin like growth factor 1 receptor	Homo sapiens	115-121
9753036-4	1998	In untreated CRF patients and healthy controls, serum SCF levels were significantly correlated with blood urea nitrogen (BUN), creatinine.	Nitrogen	111-119	KIT ligand	Homo sapiens	54-57
9721887-4	1998	The observation that sets of genetically related cell lines representing different HA binding states showed correlated differences in N-glycosylation of CD44, and that inhibition of N-glycosylation enhanced HA binding (Lesley et al., J. Exp.	Nitrogen	134-135	CD44 antigen	Mus musculus	153-157
9721887-4	1998	The observation that sets of genetically related cell lines representing different HA binding states showed correlated differences in N-glycosylation of CD44, and that inhibition of N-glycosylation enhanced HA binding (Lesley et al., J. Exp.	Nitrogen	182-183	CD44 antigen	Mus musculus	153-157
9642191-5	1998	However, the fact that Sed1p, unlike other cell wall proteins, has six cysteines and seven putative N-glycosylation sites suggests that Sed1p belongs to a new family of cell wall proteins.	Nitrogen	100-101	Sed1p	Saccharomyces cerevisiae S288C	23-28
9570794-5	1998	Similar expression experiments in other neuron-like cells and in fibroblastic cells revealed that N-glycosylation of neurexophilin 1 occurred in all cell types tested, whereas proteolytic processing was observed only in neuron-like cells.	Nitrogen	98-99	neurexophilin 1	Homo sapiens	117-132
9557657-3	1998	The havcr-1 glycoprotein contains four putative N-glycosylation sites, two in the Cys-rich region and two in the TSP-rich region.	Nitrogen	48-49	hepatitis A virus cellular receptor 1	Homo sapiens	4-11
9557657-6	1998	Treatment of AGMK and cr5 cell extracts with peptide-N-glycosidase F resulted in the collapse of the havcr-1-specific bands into a single band of 56 kDa, which indicated that different N-glycosylated forms of havcr-1 were expressed in these cells.	Nitrogen	53-54	hepatitis A virus cellular receptor 1	Homo sapiens	101-108
9557657-6	1998	Treatment of AGMK and cr5 cell extracts with peptide-N-glycosidase F resulted in the collapse of the havcr-1-specific bands into a single band of 56 kDa, which indicated that different N-glycosylated forms of havcr-1 were expressed in these cells.	Nitrogen	53-54	hepatitis A virus cellular receptor 1	Homo sapiens	209-216
9557657-11	1998	These results indicate that the Cys-rich region of havcr-1 and its first N-glycosylation site are required for binding of protective MAb 190/4 and HAV receptor function.	Nitrogen	73-74	hepatitis A virus cellular receptor 1	Homo sapiens	51-58
9573546-7	1998	Kallikrein gene delivery caused a decrease in blood urea nitrogen levels and increases in urinary kinin and nitrite/nitrate levels.	Nitrogen	57-65	kallikrein related peptidase 4	Homo sapiens	0-10
9512480-2	1998	Phosphoenolpyruvate carboxylase (PEPC) is a key enzyme in the supply of carbon skeletons for the assimilation of nitrogen by green algae.	Nitrogen	113-121	uncharacterized protein	Chlamydomonas reinhardtii	0-31
9620624-2	1998	Selective N-methylation of a racemic precursor with [11C]iodomethane and subsequent optical resolution of the racemate with HPLC afforded optically pure [11C]L-365,260 and [11C]L-365,346, which are selective for CCK-B (central-type) receptors and CCK-A (peripheral-type) receptors, respectively.	Nitrogen	10-11	cholecystokinin	Rattus norvegicus	212-215
9620624-2	1998	Selective N-methylation of a racemic precursor with [11C]iodomethane and subsequent optical resolution of the racemate with HPLC afforded optically pure [11C]L-365,260 and [11C]L-365,346, which are selective for CCK-B (central-type) receptors and CCK-A (peripheral-type) receptors, respectively.	Nitrogen	10-11	cholecystokinin	Rattus norvegicus	247-250
9510203-4	1998	There are five consensus N-linked glycosylation sites, and putative cleavage sites for factor I and C3 convertase.	Nitrogen	25-26	complement component C3	Strongylocentrotus purpuratus	100-102
9568282-1	1998	Two catalytic pathways have been proposed for the flavoenzyme monoamine oxidase B (MAO-B)--one based on an initial single electron transfer (SET) step from the nitrogen lone pair and the second based on an initial alpha-carbon hydrogen atom transfer (HAT) step.	Nitrogen	160-168	monoamine oxidase B	Homo sapiens	62-81
9568282-1	1998	Two catalytic pathways have been proposed for the flavoenzyme monoamine oxidase B (MAO-B)--one based on an initial single electron transfer (SET) step from the nitrogen lone pair and the second based on an initial alpha-carbon hydrogen atom transfer (HAT) step.	Nitrogen	160-168	monoamine oxidase B	Homo sapiens	83-88
9501134-0	1998	Expression of an arabidopsis aspartate Kinase/Homoserine dehydrogenase gene is metabolically regulated by photosynthesis-related signals but not by nitrogenous compounds Although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids.	Nitrogen	215-223	aspartate kinase-homoserine dehydrogenase ii	Arabidopsis thaliana	29-70
9501134-0	1998	Expression of an arabidopsis aspartate Kinase/Homoserine dehydrogenase gene is metabolically regulated by photosynthesis-related signals but not by nitrogenous compounds Although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids.	Nitrogen	327-335	aspartate kinase-homoserine dehydrogenase ii	Arabidopsis thaliana	29-70
9523722-5	1998	Part of the ATP-binding site of GlcNAc kinase was identified by sequence comparison with related hexokinases, including the bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (EC 5.1.3.14/2.7.1.60), the key enzyme of N-acetylneuraminic acid biosynthesis in rat liver.	Nitrogen	35-36	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase	Rattus norvegicus	144-206
9490034-3	1998	GFRalpha-3 is a protein composed of 400 amino acid residues with three potential N-linked glycosylation sites together with the features characteristic of a glycosyl-phosphatidylinositol-anchored membrane protein.	Nitrogen	81-82	GDNF family receptor alpha 3	Homo sapiens	0-10
9524359-4	1998	Lysyl oxidase is synthesized as a preproprotein, secreted as a 50 kDa, N-glycosylated proenzyme and then proteolytically cleaved to the 32 kDa, catalytically active, mature enzyme.	Nitrogen	71-72	lysyl oxidase	Homo sapiens	0-13
9405276-1	1998	The role of N-linked glycosylation on the biological activity of Schwanniomyces occidentalis SWA2 alpha-amylase, as expressed in Saccharomyces cerevisiae, was analysed by site-directed mutagenesis of the two potential N-glycosylation sites, Asn-134 and Asn-229.	Nitrogen	12-13	Swa2p	Saccharomyces cerevisiae S288C	93-97
9572394-1	1998	Multiple variant alleles of the human arylamine N-acetyltransferase genes, NAT1* and NAT2*, alter the capacity of individuals to metabolize arylamines by N-acetylation.	Nitrogen	48-49	N-acetyltransferase 2	Homo sapiens	85-89
9373251-1	1997	We have expressed a soluble N-glycosylated form of the murine interleukin-11 (IL-11) receptor alpha-chain (sIL-11R) and examined signaling in cells expressing the gp130 molecule.	Nitrogen	28-29	interleukin 11	Mus musculus	62-76
9373251-1	1997	We have expressed a soluble N-glycosylated form of the murine interleukin-11 (IL-11) receptor alpha-chain (sIL-11R) and examined signaling in cells expressing the gp130 molecule.	Nitrogen	28-29	interleukin 11	Mus musculus	78-83
9409822-2	1997	We have found that at a permissive temperature for growth, the sec13-1 mutation selectively blocks transport of the nitrogen-regulated amino acid permease, Gap1p, from the Golgi to the plasma membrane, but does not affect the activity of constitutive permeases such as Hip1p, Can1p, or Lyp1p.	Nitrogen	116-124	GTPase-activating protein SEC13	Saccharomyces cerevisiae S288C	63-68
9409822-5	1997	Mutations in LST4 and LST7 reduce the activity of the nitrogen-regulated permeases Gap1p and Put4p, whereas mutations in LST8 impair the activities of a broader set of amino acid permeases.	Nitrogen	54-62	Lst7p	Saccharomyces cerevisiae S288C	22-26
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Dal80p	Saccharomyces cerevisiae S288C	143-149
9401021-1	1997	Regulated nitrogen catabolic gene transcription in Saccharomyces cerevisiae is mediated by four positive (Gln3p and Gat1p/Nil1p) and negative (Dal80p/Uga43p and Deh1p/Nil2p/GZF3p) regulators which function in opposition to one another.	Nitrogen	10-18	Dal80p	Saccharomyces cerevisiae S288C	150-156
9443826-2	1997	Our previous study showed that N-linked sugar chains with GalNAc beta1--&gt;4GlcNAc structure appears to increase in bovine MFGM glycoproteins during early lactation [Ujita et al.	Nitrogen	31-32	milk fat globule EGF and factor V/VIII domain containing	Bos taurus	124-128
9399013-7	1997	There are three major metabolites, one of which, the N-desmethyl metabolite, is active as a 5HT1D agonist and has mean plasma concentrations approximately two thirds those of the parent compound.	Nitrogen	53-54	5-hydroxytryptamine receptor 1D	Homo sapiens	92-97
9333323-3	1997	Tunneling of NH3 may be a common mechanism for glutamine amidotransferase-catalyzed nitrogen transfer and for coordination of catalysis at two distinct active sites in complex enzymes.	Nitrogen	84-92	guanine monophosphate synthase	Homo sapiens	47-73
9278412-2	1997	Despite a low overall amino acid sequence identity of approximately 30%, it shares several features with Dal80p/Uga43p and Gzf3p/Nil2p, both repressors in nitrogen metabolism in Saccharomyces cerevisiae.	Nitrogen	155-163	Dal80p	Saccharomyces cerevisiae S288C	105-111
9278412-2	1997	Despite a low overall amino acid sequence identity of approximately 30%, it shares several features with Dal80p/Uga43p and Gzf3p/Nil2p, both repressors in nitrogen metabolism in Saccharomyces cerevisiae.	Nitrogen	155-163	Dal80p	Saccharomyces cerevisiae S288C	112-118
9337875-0	1997	Characterization of iduronate sulphatase mutants affecting N-glycosylation sites and the cysteine-84 residue.	Nitrogen	59-60	iduronate 2-sulfatase	Homo sapiens	20-40
9337875-3	1997	IDS mutant cDNAs, lacking one of the eight potential N-glycosylation sites, were expressed in COS cells.	Nitrogen	13-14	iduronate 2-sulfatase	Homo sapiens	0-3
9294006-2	1997	Mouse CD151 mRNA comprises approximately 1.8 kb, has 253 amino acid residues with 93% identity to human CD151 and contains four putative transmembrane domains, a number of cysteine residues and one potential N-glycosylation site located at a site corresponding to that in human CD151.	Nitrogen	14-15	CD151 molecule (Raph blood group)	Homo sapiens	104-109
9294006-2	1997	Mouse CD151 mRNA comprises approximately 1.8 kb, has 253 amino acid residues with 93% identity to human CD151 and contains four putative transmembrane domains, a number of cysteine residues and one potential N-glycosylation site located at a site corresponding to that in human CD151.	Nitrogen	14-15	CD151 molecule (Raph blood group)	Homo sapiens	104-109
9234685-10	1997	On a poor nitrogen source, MEP2 expression is much higher than MEP1 and MEP3 expression.	Nitrogen	10-18	ammonium permease MEP2	Saccharomyces cerevisiae S288C	27-31
9234685-11	1997	High-level MEP2 transcription requires at least one of the two GATA family factors Gln3p and Nil1p, which are involved in transcriptional activation of many other nitrogen-regulated genes.	Nitrogen	163-171	ammonium permease MEP2	Saccharomyces cerevisiae S288C	11-15
9301081-0	1997	Nitrogen and hormonal responsiveness of the 22 kDa alpha-zein and b-32 genes in maize endosperm is displayed in the absence of the transcriptional regulator Opaque-2.	Nitrogen	0-8	Ribosome-inactivating protein 9	Zea mays	66-70
9301081-3	1997	An in vitro endosperm culture system has been studied in which o2 endosperm synthesizes 22 kDa zein and b-32 in response to nitrogen supplements.	Nitrogen	124-132	Ribosome-inactivating protein 9	Zea mays	104-108
9301081-11	1997	An induction of 22 kDa zein and b-32 synthesis in cultured o2 endosperm could also be achieved on nitrogen-free media by the addition of abscisic acid or methyl jasmonate.	Nitrogen	98-106	Ribosome-inactivating protein 9	Zea mays	32-36
9316174-0	1997	Effects of genetic defects in the CYP2C19 gene on the N-demethylation of imipramine, and clinical outcome of imipramine therapy.	Nitrogen	54-55	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	34-41
9316174-6	1997	This suggests that the N-demethylation of imipramine is impaired in patients with genetic defects in the CYP2C19 gene, and that genotype determination may be useful in preventing side effects induced by unexpectedly elevated levels of imipramine.	Nitrogen	23-24	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	105-112
11670023-0	1997	Spin-Orbit Mixing and Nephelauxetic Effects in the Electronic Spectra of Nickel(II)-Encapsulating Complexes Involving Nitrogen and Sulfur Donors.	Nitrogen	118-126	spindlin 1	Homo sapiens	0-4
9232875-6	1997	These phenotypic changes could be explained by a defect in nitrogen nutrition due to the reduced peptide transport activity conferred by AtPTR2-B.	Nitrogen	59-67	peptide transporter 2	Arabidopsis thaliana	137-145
9190854-7	1997	Among the recombinant human CYPs, CYP2C19, 2C18, 2D6, 1A2, 3A4 and 2B6 in rank order catalyzed the N-demethylation, whereas CYP2D6, 2C19, 1A2, 2C18 and 3A4 catalyzed the 2-hydroxylation.	Nitrogen	99-100	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	34-41
9217112-4	1997	Cells inoculated into ground meats (beef, pork, turkey) were readily detected by enrichment for 24 h in mEC + n at 42 degrees C without shaking, followed by screening the enrichment cultures using a rapid and inexpensive commercially available enzyme immunoassay system, the E. coli O157 Rapitest.	Nitrogen	7-8	chemokine (C-C motif) ligand 28	Mus musculus	104-107
9202744-2	1997	N-Acetylation is catalyzed by two cytosolic N-acetyltransferases (NAT1 and NAT2) which detoxify many carcinogenic aromatic amines.	Nitrogen	0-1	N-acetyltransferase 2	Homo sapiens	75-79
9202757-6	1997	The N-hydroxylation of IQ appears to be carried out largely by hepatic CYP3A4 and/or CYP2C9/10, and not by CYP1A2, an isoform not expressed in liver of this species.	Nitrogen	4-5	cytochrome P450 family 2 subfamily C member 9	Macaca fascicularis	85-91
9174053-3	1997	Biochemical analysis demonstrated that the approximately 177 kDa ALK polypeptide core undergoes co-translational N-linked glycosylation, emerging in its mature form as a 200 kDa single chain receptor.	Nitrogen	113-114	ALK receptor tyrosine kinase	Homo sapiens	65-68
9175865-0	1997	Increased glucose transport in ras-transformed fibroblasts: a possible role for N-glycosylation of GLUT1.	Nitrogen	80-81	solute carrier family 2 member 1	Homo sapiens	99-104
9175865-4	1997	Nevertheless, ras-transformed GLUT1 displays a higher molecular mass due to an increased N-glycosylation of the protein.	Nitrogen	0-1	solute carrier family 2 member 1	Homo sapiens	30-35
9128148-7	1997	Analysis of the deduced amino acid sequence, which showed 32% identity with those of mammalian microsomal aminopeptidases, indicated that H11 has a short N-terminal cytoplasmic tail, a single transmembrane region and a long extracellular region with putative N-linked glycosylation sites and the HEXXHXW motif characteristic of microsomal aminopeptidases.	Nitrogen	154-155	H1.1 linker histone, cluster member	Homo sapiens	138-141
9161026-6	1997	These results suggest that, together with transcriptional control, post-transcriptional regulation by the nitrogen source is operating on NiR expression.	Nitrogen	106-114	nitrite reductase 1	Arabidopsis thaliana	138-141
9012488-12	1997	Taken together, our data suggest strongly that N-linked glycosylation plays an important role in maintenance of viability of melanoma cells through regulating the translocation of IGF-I receptor to the cell surface.	Nitrogen	47-48	insulin like growth factor 1 receptor	Homo sapiens	180-194
24022956-0	1997	Evidence for Direct trans Insertion in a Hydrido-Olefin Rhodium Complex-Free Nitrogen as a Trap in a Migratory Insertion Process.	Nitrogen	77-85	TRAP	Homo sapiens	91-95
8995380-9	1997	An N-glycosylated form of cystatin M of 20-22 kDa was co-immunoprecipitated and accounted for about 30-40% of total cystatin M protein.	Nitrogen	3-4	cystatin E/M	Homo sapiens	26-36
8995380-9	1997	An N-glycosylated form of cystatin M of 20-22 kDa was co-immunoprecipitated and accounted for about 30-40% of total cystatin M protein.	Nitrogen	3-4	cystatin E/M	Homo sapiens	116-126
8995422-1	1997	The membrane topology of GAT-1, a sodium- and chloride-coupled gamma-aminobutyric acid transporter from rat brain, has been probed using N-glycosylation scanning mutagenesis.	Nitrogen	137-138	solute carrier family 6 member 12	Rattus norvegicus	25-30
9009270-5	1997	However, the Cdc42p binding domain was necessary for filamentous growth in response to nitrogen starvation and for an essential function that Ste20p shares with its isoform Cla4p during vegetative growth.	Nitrogen	87-95	Rho family GTPase CDC42	Saccharomyces cerevisiae S288C	13-19
9143709-1	1997	H2-M3 is an MHC class Ib molecule of the mouse with a unique preference for N-formylated peptides, which may come from the N-termini of endogenous, mitochondrial proteins or foreign, bacterial proteins.	Nitrogen	76-77	histocompatibility 2, M region locus 3	Mus musculus	0-5
9473774-4	1997	Nonrestricted CD45 epitopes were not affected by the sialyl acid cleavage with sodium metaperiodate or neuraminidase, but were sensitive to both, tunicamycin, the N-glycosylation inhibitor and monensin, an inhibitor of protein transport through the Golgi compartment.	Nitrogen	0-1	protein tyrosine phosphatase receptor type C	Homo sapiens	14-18
8855938-1	1996	The crystal structure of the noncovalent complex of bovine thrombin and a fibrinogen-A alpha tridecapeptide substrate analog, G17 psi, in which the scissile bond amide nitrogen of Gly-17f has been replaced by a methylene carbon, has been determined at 2.3 A resolution with an R factor of 17.1%.	Nitrogen	168-176	coagulation factor II, thrombin	Bos taurus	59-67
8798755-1	1996	Cloning of the cDNA encoding a novel human protein- tyrosine phosphatase (PTP) called islet cell antigen-related PTP (IAR) predicts a receptor-like molecule with an extracellular domain of 614 amino acids containing a hydrophobic signal peptide, one potential N-glycosylation site, and an RGDS peptide which is a possible adhesive recognition sequence.	Nitrogen	17-18	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	43-72
8798755-1	1996	Cloning of the cDNA encoding a novel human protein- tyrosine phosphatase (PTP) called islet cell antigen-related PTP (IAR) predicts a receptor-like molecule with an extracellular domain of 614 amino acids containing a hydrophobic signal peptide, one potential N-glycosylation site, and an RGDS peptide which is a possible adhesive recognition sequence.	Nitrogen	17-18	protein tyrosine phosphatase non-receptor type 22	Homo sapiens	74-77
9047379-5	1996	The TAG-CD59 fusion protein was confirmed to be GPI-anchored, N-glycosylated and showed identical complement-inhibitory function to wild-type CD59, lacking the TAG peptide sequence.	Nitrogen	62-63	CD59a antigen	Mus musculus	8-12
8905919-4	1996	The proton nmr longitudinal relaxation rate study indicated that the paramagnetic effects of the haem iron of CYP1A2 were observed in protons of enoxacin with a 1,8-naphthyridine skeleton and its 4"-nitrogen atom on the 7-piperazine ring probably participated in specific binding to the haem iron.	Nitrogen	199-207	cytochrome P450, family 1, subfamily a, polypeptide 2	Rattus norvegicus	110-116
8756556-5	1996	PLP-D contains one putative N-glycosylation site and six cysteine residues that are highly conserved in the placental PRL family.	Nitrogen	28-29	prolactin family 8, subfamily A, member 7	Rattus norvegicus	0-5
9064341-5	1996	However, it is pronase sensitive and dependent on N-linked glycosylation of CD5, since treatment of CD5Rg with PNGaseF on N-glycanase completely abrogates its ability to bind activated splenocytes.	Nitrogen	50-51	CD5 antigen	Mus musculus	76-79
8702834-5	1996	A CGbeta gene was engineered in which the N-linked sites were inactivated to eliminate background from those carbohydrate groups.	Nitrogen	42-43	chorionic gonadotropin subunit beta 3	Homo sapiens	2-8
8707857-10	1996	We previously showed that the binding of two ligands to the cell surface N-acetylgalactosaminylphosphotransferase (GalNAcPTase), the monoclonal antibody 1B11 and a proteoglycan with a 250-kD core protein, results in the accumulation of phosphorylated tyrosine residues on beta-catenin, uncoupling of N-cadherin from its association with the actin containing cytoskeleton, and loss of N-cadherin function.	Nitrogen	73-74	catenin beta 1	Gallus gallus	272-284
8844261-5	1996	Highly homogeneous Rat Cpn10 was obtained using an optimised synthetic strategy and one-step purification procedure (method C), involving (i) HBTU/HOBt activation, (ii) N-(2-chlorobenzyloxycarbonyloxy)succinimide as capping agent and (iii) the incorporation of a reversible Fmoc-based chromatographic probe, derivatised with a lipophilic group for fast one-step RP purification, to give an overall yield of 9.6%.	Nitrogen	169-170	heat shock protein family E (Hsp10) member 1	Rattus norvegicus	23-28
8672021-10	1996	The correlation between serum pro-gastrin-releasing peptide and serum urea nitrogen concentrations was likewise significant.	Nitrogen	75-83	gastrin releasing peptide	Homo sapiens	34-59
8844829-5	1996	With the assumption that the protonated amine nitrogen, a feature common to all delta opioid ligands, interacts with the highly conserved Asp127 in TM3, a pocket was found that satisfied the criteria of complementarity to the requirements for receptor recognition for these four diverse ligands, two delta selective antagonists (the fused ring naltrindole and the peptide Tyr-Tic-Phe-Phe-NH2) and the two agonists lofentanil and BW373U86 deduced from previous studies of the ligands alone.	Nitrogen	46-54	tropomyosin 3	Homo sapiens	148-151
8655539-2	1996	A lon gene homolog from Azospirillum brasilense, a nitrogen-fixing soil bacterium which lives in association with the roots of cereal grasses, was cloned and characterized.	Nitrogen	51-59	putative ATP-dependent Lon protease	Escherichia coli	2-5
8643532-1	1996	Several epidemiologic studies indicate that NAT2-related slow N-acetylation increases bladder cancer risk among workers exposed to aromatic amines, presumably because N-acetylation is important for the detoxification of these compounds.	Nitrogen	62-63	N-acetyltransferase 2	Homo sapiens	44-48
8625679-1	1996	STUDY OBJECTIVE: To compare efficacy, side effects, patient compliance, and preference between oral appliance (OA) therapy and nasal-continuous positive airway pressure (N-CPAP) therapy.	Nitrogen	170-171	centromere protein J	Homo sapiens	172-176
8627808-2	1996	The mRNA of the SFA-1 gene is approximately 1.6 kb in size and encodes a protein of 253 amino acids, containing four putative transmembrane domains, a number of cysteine residues, and one potential N-glycosylation site in a major hydrophilic region between the third and fourth transmembrane domains.	Nitrogen	6-7	CD151 molecule (Raph blood group)	Homo sapiens	16-21
9982670-0	1996	Spin-flip Raman-scattering studies of compensating donor centers in nitrogen-doped zinc selenide grown by molecular-beam epitaxy.	Nitrogen	68-76	spindlin 1	Homo sapiens	0-4
8612696-1	1996	The N-glycosylated integral membrane protein synaptophysin is one of the major polypeptide components of small presynaptic transmitter-containing vesicles in neurons and of similar vesicles in neuroendocrine cells of mammals.	Nitrogen	4-5	synaptophysin	Homo sapiens	45-58
8631816-21	1996	The DUT-N cDNA sequence matches the previously cloned cDNAs with the exception of a few discrepancies in the 5" end.	Nitrogen	8-9	deoxyuridine triphosphatase	Homo sapiens	4-7
9206115-3	1996	This study demonstrated that ET-1 (0.1 nmol/L to 100 nmol/L) increased the [3H] thymidine uptake in a dose-dependent manner in cultured bovine pulmonary artery smooth muscle cells (PASMC), which was enhanced by exposing PASMC to hypoxia (2% O2, 93% N2, 5% CO2).	Nitrogen	249-251	endothelin 1	Bos taurus	29-33
8620724-7	1996	SP-A (in microgram/mL) was enhanced in Asb but not affected by smoking: 5.4 +/- 1.5 in Asb vs 1.6 +/- 0.4 in N (p &lt; 0.05), whereas SP-A to phosphorus ratio was increased in Asb but affected by smoking.	Nitrogen	109-110	surfactant protein A2	Homo sapiens	0-4
8636209-7	1996	Mutagenesis of N-linked glycosylation sites showed that glycosylation of CD3 gamma is not required for TCR assembly and expression.	Nitrogen	15-16	CD3 gamma subunit of T-cell receptor complex	Homo sapiens	73-82
8576155-1	1996	We have investigated the role of N-myristoylation in the activation of bovine ADP-ribosylation factor 1 (ARF1).	Nitrogen	33-34	ADP ribosylation factor 1	Bos taurus	78-103
8576155-1	1996	We have investigated the role of N-myristoylation in the activation of bovine ADP-ribosylation factor 1 (ARF1).	Nitrogen	33-34	ADP ribosylation factor 1	Bos taurus	105-109
11666171-5	1996	The coordination geometry of the iron(II) center can be described as a weakly distorted octahedron, including six nitrogen atoms originating from the two TRIM ligands coordinated to Fe(II) through their imine nitrogen atoms.	Nitrogen	114-122	T cell receptor associated transmembrane adaptor 1	Homo sapiens	154-158
11666171-5	1996	The coordination geometry of the iron(II) center can be described as a weakly distorted octahedron, including six nitrogen atoms originating from the two TRIM ligands coordinated to Fe(II) through their imine nitrogen atoms.	Nitrogen	209-217	T cell receptor associated transmembrane adaptor 1	Homo sapiens	154-158
8712396-5	1996	Rates of N-dealkylated metabolite formation significantly correlated with nifedipine oxidation activity (a marker of CYP3A4 activity) for fentanyl and sufentanil (r = 0.93 and 0.87, n = 18, respectively), but not with the oxidation activity for ethoxyresorufin (CYP1A2), S-mephenytoin (CYP2C19), bufuralol (CYP2D6), or chlorzoxazone (CYP2E1).	Nitrogen	9-10	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	286-293
8774681-1	1996	The small surface protein (S) of the hepatitis B virus (HBV) is synthesized as unglycosylated p24 and N-glycosylated gp27 and forms disulfide linked dimers.	Nitrogen	102-103	CD151 molecule (Raph blood group)	Homo sapiens	117-121
8821656-2	1996	We have identified mutations in ALG1 (ERC14), a gene required for N-glycosylation, which are inviable in a cln1 cln2 background but are rescued by over-expression of CLNs.	Nitrogen	66-67	cyclin CLN2	Saccharomyces cerevisiae S288C	112-116
8536693-5	1995	Digestion of the recombinant TIMP-1 with peptide-N-glycanaseF revealed that both N-glycosylation sites are used.	Nitrogen	49-50	TIMP metallopeptidase inhibitor 1	Rattus norvegicus	29-35
7588811-9	1995	Several lines of evidence suggest that Man9-mannosidase, as expressed, is N-glycosylated at one of three potential Asn-Xaa-Thr/Ser/Cys acceptor sites.	Nitrogen	74-75	mannosidase alpha class 1A member 1	Homo sapiens	39-55
7548083-6	1995	Specifically, the pH dependence of MLT 15N chemical shifts was measured separately for the isotopically enriched backbone nitrogen of Gly-1 and the side chain nitrogen atoms of Lys-7, Lys-21, and Lys-23 at a MLT concentration of 1.2 mM and a temperature of 23 degrees C. Measurements were made for MLT in potassium phosphate buffer, in neat water, and in 1-myristoyl-2-hydroxyl-sn-glycero-3-phosphocholine (MMPC) lipid micelles.	Nitrogen	122-130	melittin	Apis mellifera	35-38
7548083-6	1995	Specifically, the pH dependence of MLT 15N chemical shifts was measured separately for the isotopically enriched backbone nitrogen of Gly-1 and the side chain nitrogen atoms of Lys-7, Lys-21, and Lys-23 at a MLT concentration of 1.2 mM and a temperature of 23 degrees C. Measurements were made for MLT in potassium phosphate buffer, in neat water, and in 1-myristoyl-2-hydroxyl-sn-glycero-3-phosphocholine (MMPC) lipid micelles.	Nitrogen	159-167	melittin	Apis mellifera	35-38
7574684-0	1995	Extracellular domain of neurotrophin receptor trkB: disulfide structure, N-glycosylation sites, and ligand binding.	Nitrogen	73-74	brain derived neurotrophic factor	Homo sapiens	24-36
7782289-8	1995	In each case, an N-glycosylated 27-kDa protein was generated, that, like TIMP-1 and TIMP-2, inhibited collagenase-1, stromelysin-1, and gelatinases A and B.	Nitrogen	17-18	matrix metallopeptidase 2	Mus musculus	136-155
7768912-3	1995	In this report, characterization of the protein purified from mastocytomas reveals an N-glycosylated, high molecular weight, tryptic serine protease, which appears to be a tetramer of catalytic subunits, approximately half of which are linked by disulfide bonds.	Nitrogen	86-87	chymase 1	Canis lupus familiaris	133-148
7741711-7	1995	Membrane PLD activity increases within 10 min after diploid cells are placed in a sporulation-inducing medium lacking nitrogen and containing a non-fermentable carbon source.	Nitrogen	118-126	phospholipase D	Saccharomyces cerevisiae S288C	9-12
7752090-7	1995	These findings suggest that the prolonged, potent renal vasodilation was caused by a reaction of bovine serum albumin (BSA) with oxides of nitrogen to form S-nitroso-BSA.	Nitrogen	139-147	albumin	Rattus norvegicus	104-117
7758819-0	1995	N-linked glycosylation of tissue plasminogen activator in Namalwa cells.	Nitrogen	0-1	chromosome 20 open reading frame 181	Homo sapiens	26-54
7524659-5	1994	NHE2 was predicted to be N-glycosylated as it contains one potential N-linked glycosylation site (N350VS), which is conserved among NHE1, NHE3, and NHE4.	Nitrogen	0-1	sodium/hydrogen exchanger 1	Cricetulus griseus	132-136
7524659-5	1994	NHE2 was predicted to be N-glycosylated as it contains one potential N-linked glycosylation site (N350VS), which is conserved among NHE1, NHE3, and NHE4.	Nitrogen	25-26	LOW QUALITY PROTEIN: sodium/hydrogen exchanger 2	Oryctolagus cuniculus	0-4
7524659-5	1994	NHE2 was predicted to be N-glycosylated as it contains one potential N-linked glycosylation site (N350VS), which is conserved among NHE1, NHE3, and NHE4.	Nitrogen	25-26	sodium/hydrogen exchanger 1	Cricetulus griseus	132-136
7524659-6	1994	However, NHE2 was resistant to peptide:N-glycosidase F (PNGase F) and endoglycosidase H (Endo H) digestion, suggesting that NHE2 is not N-glycosylated.	Nitrogen	9-10	LOW QUALITY PROTEIN: sodium/hydrogen exchanger 2	Oryctolagus cuniculus	124-128
7969072-1	1994	Oligonucleotide-directed mutagenesis was used to mutate the two potential sites for N-linked glycosylation on the rat gamma-aminobutyric acid (GABA)A receptor alpha 1 subunit.	Nitrogen	84-85	gamma-aminobutyric acid type A receptor subunit alpha 1	Rattus norvegicus	118-166
7992511-3	1994	The product encoded by the gene, designated TTP1, is a predicted type II membrane protein of 597 amino acid residues with a short cytoplasmic NH2-terminus, a membrane-spanning region and a large COOH-terminal region containing three potential N-glycosylation sites.	Nitrogen	142-143	alpha tocopherol transfer protein	Homo sapiens	44-48
7914487-9	1994	The N/O-glycosylated IL-6 was clearly as sensitive to cathepsin-G- and gamma-GT-related activities as the unglycosylated IL-6 from Escherichia coli, thus indicating that the sugar chains did not protect the cleavage sites of the two proteases on the IL-6 molecule.	Nitrogen	4-5	inactive glutathione hydrolase 2	Homo sapiens	71-79
8036159-2	1994	Single-strand ligation PCR (sslig-PCR) demonstrated that cisplatin and nitrogen mustards reacted with guanine in an N-ras fragment with varying sequence specificity similar to that observed previously in plasmid DNA.	Nitrogen	71-79	NRAS proto-oncogene, GTPase	Homo sapiens	116-121
8070313-11	1994	The binding of N-deethylated dorzolamide to human CA-I and CA-II was competitively inhibited by dorzolamide, indicating that these compounds bind to the same binding site on CAs.	Nitrogen	15-16	carbonic anhydrase 1	Homo sapiens	50-54
8070313-11	1994	The binding of N-deethylated dorzolamide to human CA-I and CA-II was competitively inhibited by dorzolamide, indicating that these compounds bind to the same binding site on CAs.	Nitrogen	15-16	carbonic anhydrase 2	Homo sapiens	59-64
8081359-5	1994	Expression of all 15 NAT2 alleles produced immunoreactive NAT2 protein with N-acetylation activity.	Nitrogen	21-22	N-acetyltransferase 2	Homo sapiens	58-62
8182543-1	1994	Studies in our laboratory have shown that the N-acetylation activity of the human term placenta is a predominantly attributable to the NAT1 form of arylamine N-acetyltransferase (NAT).	Nitrogen	46-47	bromodomain containing 2	Homo sapiens	135-138
8166649-7	1994	The N-linked glycosylation of both serum IgA1 and IgG isolated from a group of six normal individuals was compared with that from ten patients with rheumatoid arthritis (RA).	Nitrogen	4-5	immunoglobulin heavy constant alpha 1	Homo sapiens	41-45
8136380-4	1994	Further inspection of the cytoplasmic antiproteinase amino acid sequence identified three potential N-glycosylation sites and Arg341-Cys342 as the reactive site P1-P1" residues, respectively.	Nitrogen	100-101	serpin family B member 6	Homo sapiens	26-52
11538596-0	1994	Temperature of nitrogen ice on Pluto and its implications for flux measurements.	Nitrogen	15-23	PDX1 associated lncRNA, upregulator of transcription	Homo sapiens	31-36
11538596-3	1994	(Science 261, 751-754, 1993) has shown that the profile of the 2.148-micrometers band of solid nitrogen can be used as a "thermometer" and determined the temperature of nitrogen ice on Triton to be 38(+2)-1 K.  Here we reevaluate that data and refine the temperature value to 38 +/- 1 K.  Applying the same technique to Pluto we determine that the temperature of the N2 ice on that body is 40 +/- 2 K.  Using this result we have created a nonisothermal flux model of the Pluto-Charon system.	Nitrogen	95-103	PDX1 associated lncRNA, upregulator of transcription	Homo sapiens	320-325
11538596-3	1994	(Science 261, 751-754, 1993) has shown that the profile of the 2.148-micrometers band of solid nitrogen can be used as a "thermometer" and determined the temperature of nitrogen ice on Triton to be 38(+2)-1 K.  Here we reevaluate that data and refine the temperature value to 38 +/- 1 K.  Applying the same technique to Pluto we determine that the temperature of the N2 ice on that body is 40 +/- 2 K.  Using this result we have created a nonisothermal flux model of the Pluto-Charon system.	Nitrogen	95-103	PDX1 associated lncRNA, upregulator of transcription	Homo sapiens	471-476
11538596-3	1994	(Science 261, 751-754, 1993) has shown that the profile of the 2.148-micrometers band of solid nitrogen can be used as a "thermometer" and determined the temperature of nitrogen ice on Triton to be 38(+2)-1 K.  Here we reevaluate that data and refine the temperature value to 38 +/- 1 K.  Applying the same technique to Pluto we determine that the temperature of the N2 ice on that body is 40 +/- 2 K.  Using this result we have created a nonisothermal flux model of the Pluto-Charon system.	Nitrogen	169-177	PDX1 associated lncRNA, upregulator of transcription	Homo sapiens	320-325
11538596-3	1994	(Science 261, 751-754, 1993) has shown that the profile of the 2.148-micrometers band of solid nitrogen can be used as a "thermometer" and determined the temperature of nitrogen ice on Triton to be 38(+2)-1 K.  Here we reevaluate that data and refine the temperature value to 38 +/- 1 K.  Applying the same technique to Pluto we determine that the temperature of the N2 ice on that body is 40 +/- 2 K.  Using this result we have created a nonisothermal flux model of the Pluto-Charon system.	Nitrogen	169-177	PDX1 associated lncRNA, upregulator of transcription	Homo sapiens	471-476
7532995-8	1994	On films deposited using nitrogen-containing gases, the adhesion of endothelial cells was only slightly reduced in Vn-depleted medium (as compared to attachment in medium containing unmodified serum).	Nitrogen	25-33	vitronectin	Homo sapiens	115-117
8015985-8	1994	Thus, we conclude that only a single form of full-length CGRP is found in pigs and that this peptide may be cleaved to produce potentially bioactive N- and C-terminal fragments.	Nitrogen	149-150	Calcitonin gene-related peptide	Sus scrofa	57-61
8128610-7	1994	A N-glycosylation site present in bovine, ovine and porcine IL-2 respectively, is absent in gerbil.	Nitrogen	2-3	interleukin 2	Bos taurus	60-64
10779281-2	1993	The clone HD6 contained DNA encoding a 215 residue protein which contained a predicted 17 amino acid residue leader sequence, no cysteines and a single N-glycosylation site.	Nitrogen	25-26	defensin alpha 6	Homo sapiens	10-13
8223597-8	1993	The protein sequence of the Man9-mannosidase contains three potential N-glycosylation sites of which only one site is used.	Nitrogen	70-71	mannosidase alpha class 1A member 1	Homo sapiens	28-44
8376770-5	1993	The existence of a 22-amino acid hydrophobic region located 23 amino acids from the amino terminal of the deduced protein, together with four potential N-linked glycosylation sites, characterize the deduced protein encoded by I-19 cDNA as a typical type II transmembrane glycoprotein.	Nitrogen	152-153	CD38 antigen	Mus musculus	226-230
8379944-0	1993	Lecithin:cholesterol acyltransferase: role of N-linked glycosylation in enzyme function.	Nitrogen	46-47	lecithin-cholesterol acyltransferase	Homo sapiens	0-36
8379944-3	1993	25% of the total LCAT mass, and four potential N-linked glycosylation sites have been predicted at residues 20, 84, 272 and 384 of the LCAT protein sequence.	Nitrogen	47-48	lecithin-cholesterol acyltransferase	Homo sapiens	135-139
8379944-12	1993	The results demonstrate that all four potential N-glycosylation sites in LCAT are used and the presence of carbohydrate at each site has diverse effects on the enzyme activity.	Nitrogen	48-49	lecithin-cholesterol acyltransferase	Homo sapiens	73-77
8376332-9	1993	Since the DAL and UGA genes are overexpressed and largely inducer independent in dal80 deletion mutants, we have suggested DAL80 protein negatively regulates a wide spectrum of nitrogen-catabolic gene expression, likely in conjunction with a URS element.	Nitrogen	177-185	Dal80p	Saccharomyces cerevisiae S288C	123-128
28741776-1	1993	In the green alga Chlamydomonas reinhardtii, nitrogen staravation induced a reversible increase (2-fold) in NAD-isocitrate dehydrogenase (NAD-IDH; EC 1.1.1.41) and NADP-isocitrate dehydrogenase (NADP-IDH; EC 1.1.1.42) activities.	Nitrogen	45-53	uncharacterized protein	Chlamydomonas reinhardtii	123-136
28741776-1	1993	In the green alga Chlamydomonas reinhardtii, nitrogen staravation induced a reversible increase (2-fold) in NAD-isocitrate dehydrogenase (NAD-IDH; EC 1.1.1.41) and NADP-isocitrate dehydrogenase (NADP-IDH; EC 1.1.1.42) activities.	Nitrogen	45-53	uncharacterized protein	Chlamydomonas reinhardtii	180-193
8323299-1	1993	The lysosomal membrane glycoproteins lamp-1 and lamp-2 are extensively glycosylated with a variety of different carbohydrate structures of both N-linked and O-linked type.	Nitrogen	144-145	lysosomal associated membrane protein 2	Homo sapiens	48-54
8328951-1	1993	Growth of Pseudomonas AT3 on the alkaloid atropine as its sole source of carbon and nitrogen is nitrogen-limited and proceeds by degradation of the tropic acid part of the molecule, with the metabolism of the tropine being limited to the point of release of its nitrogen.	Nitrogen	84-92	ataxin 3	Homo sapiens	22-25
8328951-1	1993	Growth of Pseudomonas AT3 on the alkaloid atropine as its sole source of carbon and nitrogen is nitrogen-limited and proceeds by degradation of the tropic acid part of the molecule, with the metabolism of the tropine being limited to the point of release of its nitrogen.	Nitrogen	96-104	ataxin 3	Homo sapiens	22-25
8328951-1	1993	Growth of Pseudomonas AT3 on the alkaloid atropine as its sole source of carbon and nitrogen is nitrogen-limited and proceeds by degradation of the tropic acid part of the molecule, with the metabolism of the tropine being limited to the point of release of its nitrogen.	Nitrogen	96-104	ataxin 3	Homo sapiens	22-25
8369438-3	1993	The epsilon-Lys-216 chemical shifts in bR555 (48 ppm) and bR568 (53 ppm) are consistent with a C = N isomerization from syn in bR555 to anti in bR568.	Nitrogen	99-100	synemin	Homo sapiens	120-123
8320232-6	1993	aatB is distinct from but hybridizes to aatA, which codes for AatA, a protein required for symbiotic nitrogen fixation.	Nitrogen	101-109	AatB	Escherichia coli	0-4
8100149-0	1993	The nitrogen of the acetamido group of colchicine modulates P-glycoprotein-mediated multidrug resistance.	Nitrogen	4-12	phosphoglycolate phosphatase	Mus musculus	60-74
8101161-4	1993	When [Ca2+]i was raised by perfusion with caffeine or under N2, activation of the protein kinase C pathway (PKC) produced a small but significant release of CK.	Nitrogen	60-62	protein kinase C, gamma	Rattus norvegicus	108-111
8495972-8	1993	Both the major components of the soluble and membrane-bound forms of porcine CD44 contained N-linked glycosylation.	Nitrogen	92-93	CD44 molecule (Indian blood group)	Homo sapiens	77-81
8498089-0	1993	Selective induction of rat liver phase II enzymes by N-heterocycle analogues of phenanthrene: a response exhibiting high correlation between UDP-glucuronosyltransferase and microsomal epoxide hydrolase activities.	Nitrogen	53-54	UDP glycosyltransferase 2 family, polypeptide B	Rattus norvegicus	141-168
8431758-1	1993	Microfluorometry was used to investigate the origin of intracellular Ca2+ ([Ca2+]i) elevation in field CA1 of gerbil hippocampal slices perfused with a glucose-free physiological medium equilibrated with a 95% N2/5% CO2 gas mixture (standard in vitro ischemia-like condition).	Nitrogen	210-212	carbonic anhydrase 1	Homo sapiens	103-106
1468573-0	1992	Human urokinase contains GalNAc beta (1-4)[Fuc alpha (1-3)]GlcNAc beta (1-2) as a novel terminal element in N-linked carbohydrate chains.	Nitrogen	28-29	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	66-75
1468573-1	1992	Structural analysis of enzymically released N-linked carbohydrate chains of human urokinase (urinary-type plasminogen activator) by 1H NMR spectroscopy and FAB-MS demonstrated that the N-linked oligosaccharides on the only N-glycosylation site contain diantennary structures with the novel GalNAc beta (1-4) [Fuc alpha (1-3)]GlcNAc beta (1-2) element in the upper or the lower branch.	Nitrogen	44-45	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	332-341
1383332-6	1992	The single N-linked glycosylation site was confirmed at a location between SCR1 and SCR2, and the multiple O-linked oligosaccharides were localized to the S/T region.	Nitrogen	11-12	RNA binding motif single stranded interacting protein 1	Homo sapiens	84-88
1322273-0	1992	N-acetylation is required for the lactotrope recruitment activity of alpha-melanocyte-stimulating hormone and beta-endorphin.	Nitrogen	0-1	proopiomelanocortin	Rattus norvegicus	69-105
1344885-1	1992	Treatment of developing bean cotyledons with the inhibitor of N-glycosylation tunicamycin enhanced the synthesis of at least two polypeptides with molecular mass 78 kDa and 97 kDa.	Nitrogen	62-63	brain expressed associated with NEDD4 1	Homo sapiens	24-28
1537807-8	1992	The cloned DNA restored the ability of a histidase structural gene mutant to grow on L-histidine as the sole nitrogen source.	Nitrogen	109-117	histidine ammonia-lyase	Homo sapiens	41-50
1348477-2	1992	Incubation of the retina in N2 medium with hyaluronidase and DNAase allows us to obtain intact photoreceptors with good purity (85-90%), yields (greater than 2 x 10(5) cells per retina), and more than 95% of them excluding Trypan blue.	Nitrogen	28-30	hyaluronidase	Anolis carolinensis	43-56
1531639-2	1992	Cell treatment with the N-glycosylation inhibitor tunicamycin generated unglycosylated CD45 polypeptides of 130 and 140 kDa.	Nitrogen	24-25	protein tyrosine phosphatase receptor type C	Homo sapiens	87-91
1747929-6	1991	Pretreatment with MC and PCB resulted in an increase in the amount of 4"-hydroxylation of PhIP and a decrease in the amount of N-hydroxylated metabolites in the urine.	Nitrogen	127-128	pyruvate carboxylase	Rattus norvegicus	25-28
1941266-0	1991	Abomasal casein infusion and exogenous somatotropin enhance nitrogen utilization by growing lambs.	Nitrogen	60-68	somatotropin	Ovis aries	39-51
1941266-1	1991	Growing Dorset wether lambs (23 kg initial body weight) were used to determine whether the magnitude of nitrogen retention response to daily administration of exogenous somatotropin is limited by post-ruminal amino acid availability in growing ruminants.	Nitrogen	104-112	somatotropin	Ovis aries	169-181
1763199-4	1991	Moreover, enzymes important in synthesis of antibiotics and proteins synthesized by soil bacteria that form nitrogen-fixing nodules in alfalfa and soybeans are homologous to 15-hydroxyprostaglandin dehydrogenase.	Nitrogen	108-116	carbonyl reductase 1	Homo sapiens	174-211
1723541-7	1991	Culture of RC-2A cells in the presence of tunicamycin (after removal of surface antigens by pronase) blocked re-expression of the epitopes recognised by all 3 mAb suggesting that they involve N-linked glycosylation.	Nitrogen	192-193	paired box 5	Homo sapiens	153-158
1776363-3	1991	Among them the rvs161 mutant (RVS for Reduced Viability upon Starvation) is sensitive to carbon, nitrogen and sulphur starvation.	Nitrogen	97-105	amphiphysin-like protein RVS161	Saccharomyces cerevisiae S288C	15-21
1652019-2	1991	Benzomorphans with an electrophilic group in the nitrogen substituent were prepared as potentially irreversible ligands for the kappa-opioid receptor.	Nitrogen	49-57	opioid receptor kappa 1	Homo sapiens	128-149
1916277-0	1991	Sequences of two adjacent genes, one (DAL2) encoding allantoicase and another (DCG1) sensitive to nitrogen-catabolite repression in Saccharomyces cerevisiae.	Nitrogen	98-106	Dcg1p	Saccharomyces cerevisiae S288C	79-83
1780951-3	1991	Unexpectedly, this superfamily of dehydrogenases has other interesting relatives: 15-hydroxyprostaglandin dehydrogenase, proteins found in nitrogen-fixing bacteria, and enzymes important in the synthesis of antibiotics.	Nitrogen	139-147	carbonyl reductase 1	Homo sapiens	82-119
1710649-12	1991	Thus, it appears that the transport strategy as well as the N-glycosylation of NS1 in insect cells infected with recombinant baculovirus were different from those of the NS1 in primate cells infected with YFV.	Nitrogen	60-61	influenza virus NS1A binding protein	Homo sapiens	79-82
2009524-5	1991	Protein sequence deduced from complementary DNA analysis suggests that GCAP contains two potential sites for asparagine (N)-linked glycosylation.	Nitrogen	120-123	alkaline phosphatase, germ cell	Homo sapiens	71-75
2001369-5	1991	The rCD4 molecule has two potential sites for N-glycosylation, Asn-271 and Asn-300.	Nitrogen	46-47	Cd4 molecule	Rattus norvegicus	4-8
1685470-8	1991	Microinjection of the same volume (1 microliter) of NS into the other side of NTS region in the same rabbit didn"t show any sign of damage as those described above.	Nitrogen	52-54	neurotensin/neuromedin N	Oryctolagus cuniculus	78-81
2017210-4	1991	Metabolic N-oxidation by cytochrome P450 is an initial activation step with subsequent transformation of the N-hydroxy metabolites to the ultimate mutagenic species by O-acetyltransferase or sulfotransferase.	Nitrogen	10-11	CAS1 domain containing 1	Homo sapiens	168-207
2017210-4	1991	Metabolic N-oxidation by cytochrome P450 is an initial activation step with subsequent transformation of the N-hydroxy metabolites to the ultimate mutagenic species by O-acetyltransferase or sulfotransferase.	Nitrogen	109-110	CAS1 domain containing 1	Homo sapiens	168-207
1840589-9	1991	CD9 antigen appears to be a 227-amino acid molecule with four hydrophobic domains and one N-glycosylation site.	Nitrogen	90-91	CD9 molecule	Homo sapiens	0-3
1832909-2	1991	G6PD activities were measured under atmospheres of both N2 and O2.	Nitrogen	56-58	glucose-6-phosphate dehydrogenase	Homo sapiens	0-4
2017186-2	1991	The cDNA sequence of mPC1 codes for a protein containing 753 amino acids and three potential N-glycosylation sites.	Nitrogen	6-7	proprotein convertase subtilisin/kexin type 1	Mus musculus	21-25
1369662-9	1991	The overall concept suggests that n-AChR desensitization at presynaptic DA sites may reduce neuronal accessibility to select exogenous neurotoxins and thus attenuate neuronal destruction.	Nitrogen	14-15	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	36-40
1725860-8	1991	One potential N-linked glycosylation site is located at the mid-region of rat and human IGFBP-4, whereas only human but not rat IGFBP-6 possesses one N-linked glycosylation site at the extreme C-terminal of the molecule.	Nitrogen	14-15	insulin like growth factor binding protein 4	Homo sapiens	88-95
1702721-3	1990	Incubation of K-562 cells with the N-glycosylation inhibitor tunicamycin blocked carbohydrate processing during biosynthesis of CD45 proteins, generating unglycosylated polypeptides similar in size to those resulting from digestion of CD45 proteins with a mixture of both N- and O-glycanases.	Nitrogen	35-36	protein tyrosine phosphatase receptor type C	Homo sapiens	128-132
1702721-3	1990	Incubation of K-562 cells with the N-glycosylation inhibitor tunicamycin blocked carbohydrate processing during biosynthesis of CD45 proteins, generating unglycosylated polypeptides similar in size to those resulting from digestion of CD45 proteins with a mixture of both N- and O-glycanases.	Nitrogen	35-36	protein tyrosine phosphatase receptor type C	Homo sapiens	235-239
1702721-7	1990	From these results we conclude that the blockade of early steps of N-glycosylation during carbohydrate processing resulted in the inhibition of subsequent incorporation of O-linked sugars on CD45 polypeptides, thus preventing the late acquisition of the CD45R0 and CD45RB determinants on the 180- and 190-kDa CD45 polypeptides.	Nitrogen	67-68	protein tyrosine phosphatase receptor type C	Homo sapiens	191-195
1702721-7	1990	From these results we conclude that the blockade of early steps of N-glycosylation during carbohydrate processing resulted in the inhibition of subsequent incorporation of O-linked sugars on CD45 polypeptides, thus preventing the late acquisition of the CD45R0 and CD45RB determinants on the 180- and 190-kDa CD45 polypeptides.	Nitrogen	67-68	protein tyrosine phosphatase receptor type C	Homo sapiens	254-258
2223825-11	1990	Reverse-phase HPLC analysis of tryptic glycopeptides of the isolated [3H]mannose-labelled transferrin receptor gave three 3H-labelled peaks, indicating that all three potential N-glycosylation sites on the receptor are utilised.	Nitrogen	177-178	transferrin	Mus musculus	90-101
2226797-1	1990	The carbohydrate structures of a genetically engineered human tissue plasminogen activator variant bearing a single N-glycosylation site at Asn 448 are reported.	Nitrogen	116-117	chromosome 20 open reading frame 181	Homo sapiens	62-90
2164637-6	1990	Disruption of the IRA2 gene resulted in (i) increased sensitivity to heat shock and nitrogen starvation, (ii) sporulation defects, and (iii) suppression of the lethality of the cdc25 mutant.	Nitrogen	84-92	Ras GTPase activating protein IRA2	Saccharomyces cerevisiae S288C	18-22
2164931-5	1990	Based on the sign of the electric field gradient, the most likely ligand sphere for the iron in native lipoxygenase consists of oxygen and nitrogen ligands in a roughly octahedral field of symmetry.	Nitrogen	139-147	linoleate 9S-lipoxygenase-4	Glycine max	103-115
2358462-4	1990	There were two N-glycosylation sites in M-ASGP-BP, the location of which were identical to those in RHL-1.	Nitrogen	15-16	C-type lectin domain containing 10A	Rattus norvegicus	40-49
2358462-4	1990	There were two N-glycosylation sites in M-ASGP-BP, the location of which were identical to those in RHL-1.	Nitrogen	15-16	asialoglycoprotein receptor 1	Rattus norvegicus	100-105
2125693-1	1990	The NPR1 gene of Saccharomyces cerevisiae plays a central role in controlling permease activity; its product is required to promote the activity of at least six distinct transport systems for nitrogenous nutrients under conditions of nitrogen catabolite derepression.	Nitrogen	192-200	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	4-8
2125693-6	1990	Therefore, NPR1-dependent positive control of nitrogen transport systems most likely involves protein phosphorylation.	Nitrogen	46-54	serine/threonine protein kinase NPR1	Saccharomyces cerevisiae S288C	11-15
2344370-10	1990	The cytosolic enzymes aldehyde oxidase and xanthine oxidase both catalysed SR 4233 reduction to SR 4317 under N2.	Nitrogen	110-112	xanthine dehydrogenase	Mus musculus	43-59
2378872-5	1990	However, dog chymase differs in being modified by N-glycosylation.	Nitrogen	50-51	chymase 1	Canis lupus familiaris	13-20
2333977-9	1990	Studies on CCK-7 analogues indicate that N-methylation of the Asp residue is responsible for the observed selectivity for CCK-A receptors.	Nitrogen	41-42	cholecystokinin A receptor	Homo sapiens	122-127
2375780-1	1990	Derivatives of antitumour anthracycline antibiotics containing N-methylurea moiety in the carbohydrate ring were obtained by the interaction of methyl isocyanate with daunorubicin, doxorubicin, carminomycin and daunorubicin derivatives, substituted at C-13 or C-14 positions.	Nitrogen	63-64	homeobox C13	Homo sapiens	252-256
2318210-13	1990	Characterization of the tryptic map of rCD4 after treatment with peptide: N-glycosidase F demonstrated that both potential N-glycosylation sites are utilized.	Nitrogen	74-75	Cd4 molecule	Rattus norvegicus	39-43
2407583-7	1990	The insulin dose required to induce the same plasma glucose decline as IGF-I (44 +/- 6 vs. 43 +/- 5%, NS) was 9-12 times lower (0.06-nmol/kg bolus + 6.4 +/- 0.6 pmol.kg-1.min-1).	Nitrogen	102-104	insulin	Canis lupus familiaris	4-11
2312438-4	1990	Silages treated with alpha-amylase had a slightly higher percentage of N-free extract (P less than .10).	Nitrogen	71-72	alpha-amylase	Zea mays	21-34
2295644-1	1990	To identify the sequence segments of the alpha 3 subunit of the neuronal nicotinic acetylcholine receptor (N-nAChR) forming the binding site for the cholinergic antagonist kappa-bungarotoxin (kappa-BGT), overlapping peptides corresponding to the complete alpha 3 sequence were tested for their ability to bind 125I-labeled kappa-BGT.	Nitrogen	107-108	cholinergic receptor nicotinic alpha 2 subunit	Rattus norvegicus	73-105
2295644-1	1990	To identify the sequence segments of the alpha 3 subunit of the neuronal nicotinic acetylcholine receptor (N-nAChR) forming the binding site for the cholinergic antagonist kappa-bungarotoxin (kappa-BGT), overlapping peptides corresponding to the complete alpha 3 sequence were tested for their ability to bind 125I-labeled kappa-BGT.	Nitrogen	107-108	cholinergic receptor nicotinic beta 1 subunit	Rattus norvegicus	109-114
2404451-5	1990	Transfection with full-length GM-CSF followed by immunoprecipitation of metabolically labeled supernatant proteins with rabbit anti-rGM-CSF antiserum yielded predominantly the 23-kDa, fully glycosylated form and small amounts of both a 29-kDa form and the 18-kDa non-N-glycosylated form.	Nitrogen	267-268	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	30-36
2404451-8	1990	Adding tunicamycin to the culture medium of cells transfected with GM-CSF(del) also yielded a single non-N-glycosylated species of about 18 kDa, but secretion was at a significantly lower level than either the 29-kDa hyperglycosylated GM-CSF(del) protein from non-tunicamycin-treated cells or the 18-kDa non-N-glycosylated full-length GM-CSF from tunicamycin-treated cells.	Nitrogen	105-106	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	67-73
2404451-8	1990	Adding tunicamycin to the culture medium of cells transfected with GM-CSF(del) also yielded a single non-N-glycosylated species of about 18 kDa, but secretion was at a significantly lower level than either the 29-kDa hyperglycosylated GM-CSF(del) protein from non-tunicamycin-treated cells or the 18-kDa non-N-glycosylated full-length GM-CSF from tunicamycin-treated cells.	Nitrogen	308-309	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	67-73
1700763-1	1990	CD53 is an N-glycosylated pan-leucocyte antigen of 35-42,000 Mr.	Nitrogen	11-12	CD53 molecule	Homo sapiens	0-4
1700763-4	1990	The CD53 molecule is likely to consist of four transmembrane regions and a major extracellular hydrophilic loop containing two potential N-glycosylation sites.	Nitrogen	137-138	CD53 molecule	Homo sapiens	4-8
33820064-6	2021	The PSP2 method is applied to a nitrogen jet impingement experiment onto a spherical model.	Nitrogen	32-40	regenerating family member 1 beta	Homo sapiens	4-8
33587587-2	2021	Hereby, a bimetallic phosphide embedded in a N and P co-doped porous carbon (FeCoP2@NPPC) material was synthesized by using sustainable biomass-derived N- and P-containing carbohydrates and non-noble metal salts as precursors.	Nitrogen	45-46	natriuretic peptide C	Homo sapiens	77-88
32890663-13	2020	The compounds having multiple heterocyclic nitrogen atoms proved to be relatively more specific towards CXCR4 inhibition as compared to CCR5.	Nitrogen	43-51	C-X-C motif chemokine receptor 4	Homo sapiens	104-109
31626532-4	2019	The PHM M site exhibits a number of unusual attributes, including a His2Met ligand set, a fluxional Cu(I)-S(Met) bond, tight binding of exogenous ligands CO and N3-, and complete coupling of oxygen reduction to substrate hydroxylation even at extremely low turnover rates.	Nitrogen	161-163	peptidylglycine alpha-amidating monooxygenase	Homo sapiens	4-7
24309420-5	2014	For N-acetylation, NAT2 could be shown to be the only isoform catalyzing the reaction in vitro hence assuming to be the only relevant enzyme for in vivo acetylation.	Nitrogen	4-5	N-acetyltransferase 2	Homo sapiens	19-23
34919957-6	2022	X-ray photoelectron spectroscopy and reaction kinetic experiments confirmed that the coordination sites of Fe and N in the Fe/CN-30 are the reactive centers for TC degradation.	Nitrogen	114-115	general transcription factor IIE subunit 1	Homo sapiens	123-125
34563526-2	2022	Nitrogen footprint (NF) is a tool to quantify the use of Nr in the environment.	Nitrogen	0-8	neurofascin	Homo sapiens	20-22
34563526-2	2022	Nitrogen footprint (NF) is a tool to quantify the use of Nr in the environment.	Nitrogen	57-59	neurofascin	Homo sapiens	20-22
34563526-3	2022	Food nitrogen footprint (FNF) accounts for the largest proportion of the total NF, and the differences between provinces in China exist objectively.	Nitrogen	5-13	neurofascin	Homo sapiens	79-81
34896359-7	2022	The synthesis and biological evaluation of a large number of nitrogen-containing bisphosphonates in the 1980s and 1990s led to the key discovery that the antiresorptive effects of these more complex analogs on osteoclasts result mostly from their potency as inhibitors of the enzyme farnesyl diphosphate synthase (FDPS/FPPS).	Nitrogen	61-69	farnesyl diphosphate synthase	Homo sapiens	283-312
34896359-7	2022	The synthesis and biological evaluation of a large number of nitrogen-containing bisphosphonates in the 1980s and 1990s led to the key discovery that the antiresorptive effects of these more complex analogs on osteoclasts result mostly from their potency as inhibitors of the enzyme farnesyl diphosphate synthase (FDPS/FPPS).	Nitrogen	61-69	farnesyl diphosphate synthase	Homo sapiens	314-318
34896359-7	2022	The synthesis and biological evaluation of a large number of nitrogen-containing bisphosphonates in the 1980s and 1990s led to the key discovery that the antiresorptive effects of these more complex analogs on osteoclasts result mostly from their potency as inhibitors of the enzyme farnesyl diphosphate synthase (FDPS/FPPS).	Nitrogen	61-69	farnesyl diphosphate synthase	Homo sapiens	319-323
34941239-0	2022	Transition Metal and N Doping on AlP Monolayers for Bifunctional Oxygen Electrocatalysts: Density Functional Theory Study Assisted by Machine Learning Description.	Nitrogen	21-22	ATHS	Homo sapiens	33-36
34955015-4	2022	For example, ruthenium hydrides supported by the iPrPNPhP ligand always form the syn isomer (where syn/anti refer to the relative orientation of the group on nitrogen and the hydride ligand on ruthenium), whereas complexes supported by iPrPNHP form the anti isomer and complexes supported by iPrPNMeP form a mixture of syn and anti isomers.	Nitrogen	158-166	synemin	Homo sapiens	99-102
34311304-6	2022	The obtained Fe and N co-doped carbon back (Fe-N/CB) catalyst has very large specific surface area and abundant accessible Fe-Nx moieties.	Nitrogen	20-21	FECB	Homo sapiens	44-51
34798465-4	2022	The present study demonstrated that PIF3 and PIF5 can slightly repress anthocyanin accumulation under NaCl, low nitrogen (-N), or 6-BA treatments; in contrast, PIF4 can significantly repress anthocyanin accumulation.	Nitrogen	112-120	phytochrome interacting factor 3-like 6	Arabidopsis thaliana	45-49
34915080-7	2022	Diets rich in n-6 PUFA, SFA and TFA increase neuroinflammation, whereas diets rich in monounsaturated fatty acids (MUFA), omega-3 (n-3) PUFA and sphingolipids (SL) can diminish neuroinflammation.	Nitrogen	14-16	pumilio RNA binding family member 3	Homo sapiens	18-22
34972198-5	2021	Loss of TSC1 and TSC2, that are negative regulators of TOR complex 1 (TORC1) in mammalian cells, resulted in altered nitrogen source-dependent growth of T. atroviride, reduced mycoparasitic overgrowth and, in the case of Deltatsc1, a diminished production of numerous secondary metabolites.	Nitrogen	117-125	TSC complex subunit 2	Homo sapiens	17-21
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Nitrogen	80-81	myeloperoxidase	Mus musculus	34-37
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Nitrogen	80-81	myeloperoxidase	Mus musculus	99-102
34944979-8	2021	We found that D-mannose modulated MPO activity via two mechanisms: directly via N-glycosylation of MPO, which boosted the MPO activity of each molecule, and indirectly by increasing H2O2 production, the main substrate for MPO.	Nitrogen	80-81	myeloperoxidase	Mus musculus	122-125
34857636-1	2021	Nitrogen-fixing organisms perform dinitrogen reduction to ammonia at an Fe-M (M = Mo, Fe, or V) cofactor (FeMco) of nitrogenase.	Nitrogen	0-8	general transcription factor IIE subunit 1	Homo sapiens	86-127
34779262-9	2021	Klotho overexpression attenuated the increases in blood pressure, serum blood urea nitrogen level, and serum creatinine level in aging mice.	Nitrogen	83-91	klotho	Mus musculus	0-6
34734313-7	2021	Relative to P fertilization alone (50 kg P ha-1 year-1), combined N and P fertilization significantly altered the soil microbial community structure and favored more active soil microbial metabolism.	Nitrogen	66-67	sodium channel epithelial 1 subunit gamma	Homo sapiens	41-47
34937899-4	2021	Here, we present a general technique to thermodynamically stabilize and electronically decouple the highly reactive spin-polarized edge states by introducing a superlattice of substitutional N-atom dopants along the edges of a ZGNR.	Nitrogen	191-192	spindlin 1	Homo sapiens	116-120
34937899-5	2021	First-principles GW calculations and scanning tunnelling spectroscopy reveal a giant spin splitting of low-lying nitrogen lone-pair flat bands by an exchange field (~850 tesla) induced by the ferromagnetically ordered edge states of ZGNRs.	Nitrogen	113-121	spindlin 1	Homo sapiens	85-89
34944613-7	2021	Cd treatment significantly increased urea nitrogen and creatinine levels, along with tp53, Bax, Nos2 and Il1b mRNA, while reduced that of Bcl2, as well as glutathione (GSH) content and glutathione peroxidase (GPx) activity.	Nitrogen	42-50	cathepsin D	Mus musculus	0-2
34831215-5	2021	We sought to determine the potential differences between the distinct FLT3-ITD variants, particularly concerning their susceptibility towards combined treatment by addressing either N-glycosylation and the heat shock protein 90 (HSP90) by 17-AAG, or by targeting the PI3K/AKT/mTOR pathway by rapamycin after treatment with VPA.	Nitrogen	182-183	FMS-like tyrosine kinase 3	Mus musculus	70-74
34391189-1	2021	The mechanism and nitrogen removal performance of anammox process under different concentrations of Ca2+ and Mg2+ were explored from the perspective of molecular biology analysis based on the metabolic changes of the second messenger cyclic diguanylate (c-di-GMP).	Nitrogen	18-26	5'-nucleotidase, cytosolic II	Homo sapiens	259-262
34656860-5	2021	We demonstrate that NPF6.2/NRT1.4 is a plasma membrane nitrate transporter phosphorylated at threonine-98 by the CIPK23 protein kinase that is a regulatory hub for nitrogen and potassium nutrition.	Nitrogen	164-172	CBL-interacting protein kinase 23	Arabidopsis thaliana	113-119
34613693-6	2021	The reaction of Ga3+-coordinated PDA-coated nanoalloys with nitrogen dioxide gas is presented as an example for demonstrating the functionality of such hybrid composites.	Nitrogen	60-68	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	16-19
34612043-6	2021	By changing the coordination atoms from highly electronegative N to low electronegative Co atoms, the prepared Pt single-atom alloy (SAA, Pt1-Co3) catalyst with ultralow Pt loading (0.06 wt %) gave a much high FDCA yield (99.6%).	Nitrogen	63-64	serum amyloid A1 cluster	Homo sapiens	133-136
34669129-6	2022	Compared with the tap water irrigation, the content of alkaline nitrogen in 5 plants increased (averagely 25.8%) after 5-year irrigation with reclaimed water.	Nitrogen	64-72	nuclear RNA export factor 1	Homo sapiens	18-21
34683473-8	2021	Intriguingly, nitrogen starvation also stimulates Med13 destruction but through a different mechanism.	Nitrogen	14-22	Ssn2p	Saccharomyces cerevisiae S288C	50-55
34473424-0	2021	Boosting Nitrogen Reduction to Ammonia on FeN4 Sites by Atomic Spin Regulation.	Nitrogen	9-17	spindlin 1	Homo sapiens	63-67
34352706-1	2021	The predicted contributions of flavin-containing monooxygenase 3 (FMO3) to drug candidate N-oxygenations can be estimated using classic base dissociation constants of the N-containing moiety.	Nitrogen	171-172	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	31-64
34352706-1	2021	The predicted contributions of flavin-containing monooxygenase 3 (FMO3) to drug candidate N-oxygenations can be estimated using classic base dissociation constants of the N-containing moiety.	Nitrogen	171-172	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	66-70
34352706-7	2021	This method, along with in silico pKa (base) values > 8.4, could prove useful for predicting the contributions of FMO3 to N-oxygenations as part of drug development.	Nitrogen	122-123	flavin containing dimethylaniline monoxygenase 3	Homo sapiens	114-118
34418081-0	2021	Azurocidin is loaded into small extracellular vesicles via its N-linked glycosylation and promotes intravasation of renal cell carcinoma cells.	Nitrogen	63-64	azurocidin 1	Homo sapiens	0-10
34418081-3	2021	Here, we examined the relationship between N-linked glycosylation and AZU1 loading into small EVs (SEVs).	Nitrogen	43-44	azurocidin 1	Homo sapiens	70-74
34418081-4	2021	Inhibition of N-linked glycosylation by introducing mutations in three glycosylation sites inhibited AZU1 loading into SEVs.	Nitrogen	14-15	azurocidin 1	Homo sapiens	101-105
34418081-7	2021	Collectively, we found that N-linked glycosylation of AZU1 directs its loading into SEVs, thereby enabling AZU1-positive SEVs to function as potent permeabilizers of endothelial cells and leading to enhanced transendothelial migration of RCC cells.	Nitrogen	28-29	azurocidin 1	Homo sapiens	54-58
34418081-7	2021	Collectively, we found that N-linked glycosylation of AZU1 directs its loading into SEVs, thereby enabling AZU1-positive SEVs to function as potent permeabilizers of endothelial cells and leading to enhanced transendothelial migration of RCC cells.	Nitrogen	28-29	azurocidin 1	Homo sapiens	107-111
34499407-0	2021	Synergistic Enhancement of Electrocatalytic Nitrogen Reduction Over Boron Nitride Quantum Dots Decorated Nb2 CTx -MXene.	Nitrogen	44-52	contactin 5	Homo sapiens	105-108
34679873-3	2021	The PRCP supply was calculated from in situ rumen-undegraded CP and in vitro organic matter digestibility (i.e., reference method), from ammonia-nitrogen release during in vitro incubation (i.e., in vitro method), and from the concentrations of chemical CP fractions (i.e., chemical method).	Nitrogen	145-153	prolylcarboxypeptidase	Bos taurus	4-8
34584137-3	2021	Analysis of the intracellular localization of ANKRD22 mutants C-terminally fused to glycosylatable tumor necrosis factor (GLCTNF) and assessment of their susceptibility to protein N-glycosylation revealed that ANKRD22 is synthesized on the endoplasmic reticulum (ER) membrane as an N-myristoylated hairpin-like monotopic membrane protein with the amino- and carboxyl termini facing the cytoplasm and then sorted to LD.	Nitrogen	180-181	ankyrin repeat domain 22	Homo sapiens	210-217
34584137-3	2021	Analysis of the intracellular localization of ANKRD22 mutants C-terminally fused to glycosylatable tumor necrosis factor (GLCTNF) and assessment of their susceptibility to protein N-glycosylation revealed that ANKRD22 is synthesized on the endoplasmic reticulum (ER) membrane as an N-myristoylated hairpin-like monotopic membrane protein with the amino- and carboxyl termini facing the cytoplasm and then sorted to LD.	Nitrogen	282-283	ankyrin repeat domain 22	Homo sapiens	210-217
34584137-7	2021	Thus, multiple factors, including hairpin-like monotopic membrane topology, C-terminal positively charged residues, and protein N-myristoylation cooperatively affected the intracellular targeting of ANKRD22 to LD.	Nitrogen	128-129	ankyrin repeat domain 22	Homo sapiens	199-206
34465083-6	2021	The results provide the following insights into the effects of the bridging unit (sulfur vs oxygen) and the dibenzo-annulation on the spin delocalization in the bridged triarylamine radical cations: (1) An effective decrease of the spin density on the nitrogen atom is observed for the sulfur bridge relative to the oxygen bridge; and (2) a moderate decrease of the spin density on the oxygen atom rather than the nitrogen atom is induced by the dibenzo-annulation.	Nitrogen	252-260	spindlin 1	Homo sapiens	134-138
34465083-6	2021	The results provide the following insights into the effects of the bridging unit (sulfur vs oxygen) and the dibenzo-annulation on the spin delocalization in the bridged triarylamine radical cations: (1) An effective decrease of the spin density on the nitrogen atom is observed for the sulfur bridge relative to the oxygen bridge; and (2) a moderate decrease of the spin density on the oxygen atom rather than the nitrogen atom is induced by the dibenzo-annulation.	Nitrogen	252-260	spindlin 1	Homo sapiens	232-236
34433160-5	2021	And we identified one novel 3D extended puckered poly-nitrogen network in the P21/c-ScN5 structure, which is similar to the C2/m-ScN5.	Nitrogen	54-62	vacuolar protein sorting 45 homolog	Homo sapiens	84-88
34433160-5	2021	And we identified one novel 3D extended puckered poly-nitrogen network in the P21/c-ScN5 structure, which is similar to the C2/m-ScN5.	Nitrogen	54-62	vacuolar protein sorting 45 homolog	Homo sapiens	129-133
34433160-6	2021	The decomposition of P21/c-ScN5 to ScN and N2 under ambient pressure was estimated to release 5.02 eV energy per formula unit(f.u.	Nitrogen	43-45	vacuolar protein sorting 45 homolog	Homo sapiens	27-31
34147727-8	2021	Nitrate decrease MDA by reducing the activities of superoxide dismutase, peroxidase, and catalase in root of the N-efficient genotype.	Nitrogen	113-114	catalase-3-like	Brassica napus	89-97
34452584-6	2021	Compared with euglycemic saline-treated controls, the diabetic mice exposed to Cd demonstrated decreased body weight and increased blood urea nitrogen levels along with histopathological renal architecture changes including collagen fiber accumulation.	Nitrogen	142-150	cathepsin D	Mus musculus	79-81
34733488-0	2021	Small-interfering RNA for c-Jun attenuates cell death by preventing JNK-dependent PARP1 cleavage and DNA fragmentation in nitrogen mustard-injured immortalized human bronchial epithelial cells.	Nitrogen	122-130	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	26-31
34733488-3	2021	Here, we report that JNK/c-Jun was activated in immortalized human bronchial epithelial (HBE) cells exposed to a lethal dose (20 muM) of nitrogen mustard (NM, a sulfur mustard analog).	Nitrogen	137-145	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	25-30
34527690-2	2021	The indicator of food nitrogen footprint (NF) reflects the amount of reactive nitrogen (Nr) emissions and impacts of these emissions on the environment.	Nitrogen	22-30	neurofascin	Homo sapiens	42-44
34527690-2	2021	The indicator of food nitrogen footprint (NF) reflects the amount of reactive nitrogen (Nr) emissions and impacts of these emissions on the environment.	Nitrogen	78-86	neurofascin	Homo sapiens	42-44
34527690-2	2021	The indicator of food nitrogen footprint (NF) reflects the amount of reactive nitrogen (Nr) emissions and impacts of these emissions on the environment.	Nitrogen	88-90	neurofascin	Homo sapiens	42-44
34088166-1	2021	Nanofiltration (NF) concentrate generated from the secondary wastewater treatment contains high concentration of ammonium nitrogen and refractory organics, thus having great environmental risks.	Nitrogen	122-130	neurofascin	Homo sapiens	16-18
34260214-3	2021	For 107 countries, we analyze the colocation of human-derived nutrients (in urine) and crop demands for nitrogen, phosphorus, and potassium.	Nitrogen	104-112	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	87-91
34588115-3	2021	While the physiological importance of iron (Fe) in electron transport and N-fixation is well known, relatively little is known about its impacts on the growth of freshwater cyanobacteria.	Nitrogen	74-75	general transcription factor IIE subunit 1	Homo sapiens	44-46
34588115-5	2021	In this study, the effects of supply N:P and Fe on the growth and ionome of Dolichospermum, a nitrogen-fixing cyanobacterium found in freshwater ecosystems, were examined.	Nitrogen	94-102	general transcription factor IIE subunit 1	Homo sapiens	45-47
34588115-9	2021	Changes in Fe supply had a significant effect on yield in N-limited conditions (N:P = 5).	Nitrogen	58-59	general transcription factor IIE subunit 1	Homo sapiens	11-13
34588115-9	2021	Changes in Fe supply had a significant effect on yield in N-limited conditions (N:P = 5).	Nitrogen	80-81	general transcription factor IIE subunit 1	Homo sapiens	11-13
34360699-7	2021	We found that astrocytes and astrocyte-derived extracellular vesicles contain a set of proteins, to which Rai contributes, that are involved in the regulation of oligodendrocyte differentiation and myelination, nitrogen metabolism, and oxidative stress.	Nitrogen	211-219	src homology 2 domain-containing transforming protein C3	Mus musculus	106-109
34289370-0	2021	The histone chaperone HIR maintains chromatin states to control nitrogen assimilation and fungal virulence.	Nitrogen	64-72	potassium inwardly rectifying channel subfamily J member 4	Homo sapiens	22-25
34289370-5	2021	Genetic ablation of HIR function alters chromatin accessibility linked to aberrant transcriptional responses to protein as nitrogen source.	Nitrogen	123-131	potassium inwardly rectifying channel subfamily J member 4	Homo sapiens	20-23
34109953-3	2021	The Co-N-Ni3S2/NF is successfully synthesized for the first time by a one-step hydrothermal method, wherein nickel foam, thioacetamide and Co(NO3)2 6H2O are used as the nickel source, sulfur source, nitrogen source and cobalt source.	Nitrogen	199-207	neurofascin	Homo sapiens	9-17
34086475-0	2021	Dissociative Adsorption of N2 onto Size-Selected Tin+ and TinO+ (n <= 16) toward Nitrogen Fixation.	Nitrogen	27-29	mex-3 RNA binding family member D	Homo sapiens	58-62
34086475-0	2021	Dissociative Adsorption of N2 onto Size-Selected Tin+ and TinO+ (n <= 16) toward Nitrogen Fixation.	Nitrogen	81-89	mex-3 RNA binding family member D	Homo sapiens	58-62
34130459-6	2021	Above 120 GPa, the NF compound with polymeric zigzag nitrogen chains is discovered, and it is quenchable to the ambient conditions, acquiring the highest energy density of 5.38 kJ/g among reported binary covalent nitrogen compounds.	Nitrogen	53-61	neurofascin	Homo sapiens	19-21
34130459-6	2021	Above 120 GPa, the NF compound with polymeric zigzag nitrogen chains is discovered, and it is quenchable to the ambient conditions, acquiring the highest energy density of 5.38 kJ/g among reported binary covalent nitrogen compounds.	Nitrogen	213-221	neurofascin	Homo sapiens	19-21
34178943-7	2021	We have newly identified systemic site-specific N-glycosylation alterations underlying T2D patients in the complement activation pathways, including decreased levels of N-glycopeptides from C1s, MASP1, and CFP proteins, and increased levels of N-glycopeptides from C2, C4, C4BPA, C4BPB, and CFH.	Nitrogen	48-49	complement factor H	Homo sapiens	291-294
35341854-4	2022	The bulk deposition fluxes of total nitrogen (TN) and total phosphorus (TP) over the network were 27.5 kg N ha-1 yr-1 and 0.92 kg P ha-1 yr-1, respectively.	Nitrogen	36-44	sodium channel epithelial 1 subunit gamma	Homo sapiens	130-141
35364046-7	2022	Ngb is involved in cellular oxygen homeostasis and reactive oxygen/nitrogen scavenging in the central and peripheral nervous systems, but its functions in schistosome parasites have not yet been characterized.	Nitrogen	67-75	neuroglobin	Homo sapiens	0-3
35182648-3	2022	The ship emission ratio of HONO/nitrogen oxides (NOx) (1.21 +- 0.99%) was calculated from hundreds of night-time fresh plume measurements.	Nitrogen	32-40	inositol polyphosphate-5-phosphatase D	Homo sapiens	4-8
35274310-6	2022	A nitrite reductase-deficient strain that excludes NO3 - but absorbs NH4 + , decreased NH4 + levels in Arabidopsis shoots and rescued plant growth and nitrogen metabolism under high NH4 + levels.	Nitrogen	151-159	nitrite reductase 1	Arabidopsis thaliana	2-19
35561251-0	2022	Endohedral sigma-Diradical Nitrogen-Vacancy Diamond Nanoclusters with a Confined Magnetic Space and Strong Electronic Spin Couplings.	Nitrogen	27-35	spindlin 1	Homo sapiens	118-122
35620110-0	2022	Chromatin Regulators Ahc1p and Eaf3p Positively Influence Nitrogen Metabolism in Saccharomyces cerevisiae.	Nitrogen	58-66	Ahc1p	Saccharomyces cerevisiae S288C	21-26
35620110-0	2022	Chromatin Regulators Ahc1p and Eaf3p Positively Influence Nitrogen Metabolism in Saccharomyces cerevisiae.	Nitrogen	58-66	Eaf3p	Saccharomyces cerevisiae S288C	31-36
35620110-4	2022	Functional analysis showed that among the CRs identified, Ahc1p and Eaf3p promoted the utilization of non-preferred nitrogen sources through global regulation of nitrogen metabolism.	Nitrogen	116-124	Ahc1p	Saccharomyces cerevisiae S288C	58-63
35620110-4	2022	Functional analysis showed that among the CRs identified, Ahc1p and Eaf3p promoted the utilization of non-preferred nitrogen sources through global regulation of nitrogen metabolism.	Nitrogen	116-124	Eaf3p	Saccharomyces cerevisiae S288C	68-73
35620110-4	2022	Functional analysis showed that among the CRs identified, Ahc1p and Eaf3p promoted the utilization of non-preferred nitrogen sources through global regulation of nitrogen metabolism.	Nitrogen	162-170	Ahc1p	Saccharomyces cerevisiae S288C	58-63
35013954-7	2022	Komagataeibacter and Bacillus played a major role in nitrogen fixation in CK and T, respectively.	Nitrogen	53-61	cytidine/uridine monophosphate kinase 1	Homo sapiens	74-76
35013954-9	2022	The nosZ gene, which converts nitrous oxide to nitrogen, was found only in T. Network analysis suggested that the average number of neighbours in T was 3.30% higher than that in CK and the characteristic path length in T was 14.15% higher than that in CK.	Nitrogen	47-55	cytidine/uridine monophosphate kinase 1	Homo sapiens	178-180
35446597-2	2022	Commercial N2 washout devices are usually based on indirect measurement of N2 concentration (CN2), by directly measuring either molar mass and O2 and CO2, or molar mass and CO2.	Nitrogen	11-13	carnosine dipeptidase 2	Homo sapiens	93-96
35446597-2	2022	Commercial N2 washout devices are usually based on indirect measurement of N2 concentration (CN2), by directly measuring either molar mass and O2 and CO2, or molar mass and CO2.	Nitrogen	75-77	carnosine dipeptidase 2	Homo sapiens	93-96
35170175-4	2022	The method involves PdI2, simple alkyl monophosphines, such as tricyclohexylphosphine, and common green solvents, enabling the title reaction to occur with isoselectivity in up to 50:1 iso/n product ratios under industrially relevant conditions (80-120 omicronC).	Nitrogen	189-190	peptidyl arginine deiminase 2	Homo sapiens	20-24
35481152-0	2022	Editorial: Nitrogen Use Efficiency and Sustainable Nitrogen Management in Crop Plants.	Nitrogen	11-19	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	74-78
35481152-0	2022	Editorial: Nitrogen Use Efficiency and Sustainable Nitrogen Management in Crop Plants.	Nitrogen	51-59	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	74-78
35361113-5	2022	Irrespective of the irrigation water, RubisCo, glutamine synthase (GS), nitrate reductase (NR), nitrite reductase (NiR), and glutamate synthase (GOGAT) activities increased with increasing N fertilizer up to the V9 growth stage and decreased with approaching the maturity stage (R6) in maize.	Nitrogen	189-190	ferredoxin-dependent glutamate synthase, chloroplastic	Zea mays	125-143
34995622-3	2022	Herein, Cu-coupled Fe/Fe3C covered with carbon layer on carbon felt (Cu-Fe/Fe3C@C), engineered by a hydrothermal reaction followed by the consequent thermal-treatment in N2 atmosphere, as a self-supported integrated cathode were used for an onsite oxygen reduction reaction and a Fenton oxidation reaction.	Nitrogen	170-172	general transcription factor IIE subunit 1	Homo sapiens	19-21
34995622-3	2022	Herein, Cu-coupled Fe/Fe3C covered with carbon layer on carbon felt (Cu-Fe/Fe3C@C), engineered by a hydrothermal reaction followed by the consequent thermal-treatment in N2 atmosphere, as a self-supported integrated cathode were used for an onsite oxygen reduction reaction and a Fenton oxidation reaction.	Nitrogen	170-172	general transcription factor IIE subunit 1	Homo sapiens	72-74
35557761-5	2022	The coexistence of a lone pair electron on the nitrogen atom and a hydrogen-bonding donor (the protonated form of nitrogen and hydroxyl group) affords proximity between hPAG and O2.	Nitrogen	47-55	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	Homo sapiens	169-173
35557761-5	2022	The coexistence of a lone pair electron on the nitrogen atom and a hydrogen-bonding donor (the protonated form of nitrogen and hydroxyl group) affords proximity between hPAG and O2.	Nitrogen	114-122	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	Homo sapiens	169-173
35399505-4	2022	Vim-/- colons also produced more reactive oxygen and nitrogen species, possibly contributing to the pathogenesis of gut inflammation and tumorigenesis than in WT mice.	Nitrogen	53-61	vimentin	Mus musculus	0-3
35301431-0	2022	Hypoxia-induced GLT8D1 promotes glioma stem cell maintenance by inhibiting CD133 degradation through N-linked glycosylation.	Nitrogen	101-102	prominin 1	Mus musculus	75-80
35301431-6	2022	We reveal that GLT8D1 impedes CD133 degradation through the endosomal-lysosomal pathway by N-linked glycosylation and protein-protein interaction.	Nitrogen	91-92	prominin 1	Mus musculus	30-35
35212342-3	2022	Therein, we observed two deuteron quadrupole coupling constant for the ND bond of the TEA cation, indicating differently strong hydrogen bonds to the nitrogen and oxygen atoms of the NTf2 anion, as we could confirm by DFT calculations.	Nitrogen	150-158	nuclear transport factor 2	Homo sapiens	183-187
35381652-7	2022	Results: The median (interquartile) relative concentrations of plasma n-3 PUFA C22:5n-3 was significantly lower in women with GDM 0.87 (0.72, 1.07) compared with women without GDM 0.94 (0.75, 1.19)(P=0.001).	Nitrogen	70-71	pumilio RNA binding family member 3	Homo sapiens	74-78
35381652-8	2022	Plasma n-3 PUFA C22:5n-3 was inversely associated with GDM, with an OR (95%CI) of 0.75 (0.62-0.90) for each SD increase of relative concentration.	Nitrogen	7-8	pumilio RNA binding family member 3	Homo sapiens	11-15
35311117-8	2022	Altogether, TGF-beta1 activated c-Jun/STT3A signaling pathway to promote N-glycosylation of PD-L1, thus further facilitating immune evasion and reducing the efficacy of cancer immunotherapy.	Nitrogen	73-74	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	32-37
35240690-12	2022	Results suggest that n-3 PUFA supplementation mitigated metabolic alterations associated with IR and pre-slaughter-related stress.	Nitrogen	21-22	PUFA	Bos taurus	25-29
35217687-2	2022	The low atomic number of nitrogen atom suggests, that spin-orbit coupling in nitrogene is weak, similar to graphene or silicene.	Nitrogen	25-33	spindlin 1	Homo sapiens	54-58
35197312-0	2022	CYP2C19 plays a major role in the hepatic N-oxidation of cotinine.	Nitrogen	42-43	cytochrome P450 family 2 subfamily C member 19	Homo sapiens	0-7
35190688-1	2022	High-redox-potential reactive oxygen species and reactive nitrogen species (ROS/RNS), generated by NADPH oxidase-2 (NOX2), myeloperoxidase (MPO) and related enzymes, are key effector molecules of innate immunity.	Nitrogen	58-66	cytochrome b-245 beta chain	Homo sapiens	99-114
35190688-1	2022	High-redox-potential reactive oxygen species and reactive nitrogen species (ROS/RNS), generated by NADPH oxidase-2 (NOX2), myeloperoxidase (MPO) and related enzymes, are key effector molecules of innate immunity.	Nitrogen	58-66	cytochrome b-245 beta chain	Homo sapiens	116-120
35204242-8	2022	Furthermore, BD exposure increased the expression of uncoupled endothelial nitric oxide synthase (eNOS) by increasing reactive nitrogen species generation and the nitration of tyrosine proteins.	Nitrogen	127-135	nitric oxide synthase 3	Rattus norvegicus	63-96
35204242-8	2022	Furthermore, BD exposure increased the expression of uncoupled endothelial nitric oxide synthase (eNOS) by increasing reactive nitrogen species generation and the nitration of tyrosine proteins.	Nitrogen	127-135	nitric oxide synthase 3	Rattus norvegicus	98-102
35142070-9	2022	Further, the following structural features were beneficial for kappa-opioid receptor activation: a methylene group between the amide group and the aromatic ring, a pyrrolidine residue at the amine nitrogen of the cyclohexane ring, a methyl group at the amide nitrogen, and/or a chlorine substitution at the 3,4-position of the aromatic ring.	Nitrogen	197-205	opioid receptor kappa 1	Homo sapiens	63-84
35142070-9	2022	Further, the following structural features were beneficial for kappa-opioid receptor activation: a methylene group between the amide group and the aromatic ring, a pyrrolidine residue at the amine nitrogen of the cyclohexane ring, a methyl group at the amide nitrogen, and/or a chlorine substitution at the 3,4-position of the aromatic ring.	Nitrogen	259-267	opioid receptor kappa 1	Homo sapiens	63-84
35099917-3	2022	The crystallizations of perovskites are optimized by these molecules, and the perovskite films with low trap density are obtained by forming Lewis adducts with these molecules (Pb2+ and electron-donating groups including -NH2, C N-, and C O; I- and electron-withdrawing groups including F, Cl, N-H, and O-H).	Nitrogen	294-295	TRAP	Homo sapiens	104-108
35048936-3	2022	Benefiting from the hierarchical structure, the exposure of more active sites and the doping effect of N and Fe, the N-Fe-Ni3S2@NiP2/NF material showed excellent electrocatalytic activity for the OER and UOR.	Nitrogen	103-104	neurofascin	Homo sapiens	133-135
35222844-6	2022	Remarkably, the nucleoside antibiotic tunicamycin, which targets UDP-N-acetylglucosamine:dolichyl-phosphate N-acetylglucosaminephosphotransferase (ALG7) and N-glycosylation in other organisms, induces a delayed-death effect and inhibits parasite growth during the second IDC after treatment.	Nitrogen	157-158	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Homo sapiens	147-151
35075565-9	2022	The NiO-CaO5/SiO2-Al2O3 catalyst rendered stable reusability for five consecutive runs with liquid hydrocarbon yield within the range of 66-75% with n-(C15 + C17) selectivity of 64-72%.	Nitrogen	149-150	placenta associated 8	Homo sapiens	152-155
35001686-10	2022	Body mass index, fasting plasma glucose (FPG), hemoglobina1c (HbA1C), blood urea nitrogen (BUN) and diabetic durations were positively correlated with the serum concentration of VASH-1 (all P < 0.05).	Nitrogen	81-89	vasohibin 1	Homo sapiens	178-184