PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32254700-3 2018 Initially, the enzyme acetylcholinesterase (AChE) immobilized on the CdS/PEDOT photoanode could hydrolyze acetylthiocholine iodide (ATCh) into thiocholine as the electron donor to enhance the charge separation efficiency; thus, PEFC produced relatively high open circuit voltage (EOCV) upon illumination. acetylthiocholine iodide 106-130 CDP-diacylglycerol synthase 1 Homo sapiens 69-72 32254700-3 2018 Initially, the enzyme acetylcholinesterase (AChE) immobilized on the CdS/PEDOT photoanode could hydrolyze acetylthiocholine iodide (ATCh) into thiocholine as the electron donor to enhance the charge separation efficiency; thus, PEFC produced relatively high open circuit voltage (EOCV) upon illumination. acetylthiocholine iodide 106-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 44-48 32833082-15 2020 When AChE is present, acetylthiocholine iodide (ATCh) is hydrolyzed to thiocholine (TCh) with reducibility for decomposing MnO2 nanosheets. acetylthiocholine iodide 22-46 acetylcholinesterase (Cartwright blood group) Homo sapiens 5-9 31325829-4 2019 The presence of NACs (up to 0.5 mM) effectively suppressed the AChE-catalyzed hydrolysis of acetylthiocholine iodide, with the suppression effect increasing with the nitro-group substitution (TNB > DNB > NB). acetylthiocholine iodide 92-116 acetylcholinesterase (Cartwright blood group) Homo sapiens 63-67 32254700-3 2018 Initially, the enzyme acetylcholinesterase (AChE) immobilized on the CdS/PEDOT photoanode could hydrolyze acetylthiocholine iodide (ATCh) into thiocholine as the electron donor to enhance the charge separation efficiency; thus, PEFC produced relatively high open circuit voltage (EOCV) upon illumination. acetylthiocholine iodide 132-136 acetylcholinesterase (Cartwright blood group) Homo sapiens 44-48 32254700-3 2018 Initially, the enzyme acetylcholinesterase (AChE) immobilized on the CdS/PEDOT photoanode could hydrolyze acetylthiocholine iodide (ATCh) into thiocholine as the electron donor to enhance the charge separation efficiency; thus, PEFC produced relatively high open circuit voltage (EOCV) upon illumination. acetylthiocholine iodide 132-136 CDP-diacylglycerol synthase 1 Homo sapiens 69-72 26979315-4 2016 The biosensor showed an oxidation peak at +0.83 V related to the oxidation of thiocholine, hydrolysis product of acetylthiocholine iodide (ATCI), catalyzed by AChE. acetylthiocholine iodide 113-137 acetylcholinesterase (Cartwright blood group) Homo sapiens 159-163 26979315-4 2016 The biosensor showed an oxidation peak at +0.83 V related to the oxidation of thiocholine, hydrolysis product of acetylthiocholine iodide (ATCI), catalyzed by AChE. acetylthiocholine iodide 139-143 acetylcholinesterase (Cartwright blood group) Homo sapiens 159-163 24251311-3 2014 The fluorescence of the AuNCs was quenched by thiocholine that was produced from the AChE hydrolysis of S-acetylthiocholine iodide (ACTI) to detect the AChE activity. acetylthiocholine iodide 104-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-89 26839417-1 2016 A successful prescription is presented for acetylcholinesterase physically adsorbed on to a mesoporous silicon surface, with a promising hydrolytic response towards acetylthiocholine iodide. acetylthiocholine iodide 165-189 acetylcholinesterase (Cartwright blood group) Homo sapiens 43-63 25816587-2 2014 These compounds were reversible inhibitors of cholinesterase (ChE) of human erythrocytes, horse serum, brain of the frog Rana temporaria and visual ganglia of the Pacific squid Todarodes pacificus in the presence of acetylthiocholine iodide and propionylthiocholine iodide as substrates. acetylthiocholine iodide 216-240 butyrylcholinesterase Homo sapiens 46-60 25816587-2 2014 These compounds were reversible inhibitors of cholinesterase (ChE) of human erythrocytes, horse serum, brain of the frog Rana temporaria and visual ganglia of the Pacific squid Todarodes pacificus in the presence of acetylthiocholine iodide and propionylthiocholine iodide as substrates. acetylthiocholine iodide 216-240 butyrylcholinesterase Homo sapiens 62-65 24433789-3 2014 Plasma cholinesterase was characterized using three substrates (acetylthiocholine iodide, propionylthiocholine iodide, and S-butyrylthiocholine iodide) and three cholinesterase inhibitors (eserine sulfate, BW284C51 and iso-OMPA). acetylthiocholine iodide 64-88 cholinesterase Oryctolagus cuniculus 7-21 24251311-3 2014 The fluorescence of the AuNCs was quenched by thiocholine that was produced from the AChE hydrolysis of S-acetylthiocholine iodide (ACTI) to detect the AChE activity. acetylthiocholine iodide 104-130 acetylcholinesterase (Cartwright blood group) Homo sapiens 152-156 24251311-3 2014 The fluorescence of the AuNCs was quenched by thiocholine that was produced from the AChE hydrolysis of S-acetylthiocholine iodide (ACTI) to detect the AChE activity. acetylthiocholine iodide 132-136 acetylcholinesterase (Cartwright blood group) Homo sapiens 85-89 24251311-3 2014 The fluorescence of the AuNCs was quenched by thiocholine that was produced from the AChE hydrolysis of S-acetylthiocholine iodide (ACTI) to detect the AChE activity. acetylthiocholine iodide 132-136 acetylcholinesterase (Cartwright blood group) Homo sapiens 152-156 23494216-8 2013 K(m), V(max), optimum pH and optimum temperature for acetylcholinesterase were found by means of graphics for acetylthiocholine iodide as the substrate. acetylthiocholine iodide 110-134 acetylcholinesterase (Cartwright blood group) Homo sapiens 53-73 23494216-9 2013 The optimum pH and optimum temperature of the acetylcholinesterase were determined to be 7.4 and 25-35 C. The Michaelis-Menten constant (K(m)) for the hydrolysis of acetylthiocholine iodide was found to be 0.25 mM, and the V(max) was 0.090 mumol/mL/min. acetylthiocholine iodide 166-190 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-66 22229321-3 2011 AChE activity was assessed by measuring the hydrolysis of acetylthiocholine iodide (ASChI). acetylthiocholine iodide 58-82 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 16971069-1 2006 Pralidoxime iodide (2-PAM), an antidote approved for the reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning, dose-dependently hydrolyzed an acetylthiocholine iodide (ASCh). acetylthiocholine iodide 172-196 peptidylglycine alpha-amidating monooxygenase Homo sapiens 22-25 19708709-1 2009 By making use of the aggregation-induced emission feature of compound 1 and the cascade reactions among acetylthiocholine iodide (ATC), AChE, and compound 2, a new fluorescence "turn-on" method is developed for AChE assay and inhibitor-screening. acetylthiocholine iodide 104-128 acetylcholinesterase (Cartwright blood group) Homo sapiens 211-215 19708709-1 2009 By making use of the aggregation-induced emission feature of compound 1 and the cascade reactions among acetylthiocholine iodide (ATC), AChE, and compound 2, a new fluorescence "turn-on" method is developed for AChE assay and inhibitor-screening. acetylthiocholine iodide 130-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 136-140 19708709-1 2009 By making use of the aggregation-induced emission feature of compound 1 and the cascade reactions among acetylthiocholine iodide (ATC), AChE, and compound 2, a new fluorescence "turn-on" method is developed for AChE assay and inhibitor-screening. acetylthiocholine iodide 130-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 211-215 16971069-1 2006 Pralidoxime iodide (2-PAM), an antidote approved for the reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning, dose-dependently hydrolyzed an acetylthiocholine iodide (ASCh). acetylthiocholine iodide 172-196 acetylcholinesterase (Cartwright blood group) Homo sapiens 83-103 16971069-1 2006 Pralidoxime iodide (2-PAM), an antidote approved for the reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning, dose-dependently hydrolyzed an acetylthiocholine iodide (ASCh). acetylthiocholine iodide 172-196 acetylcholinesterase (Cartwright blood group) Homo sapiens 105-109 20021020-3 2006 Cholinesterase was spectrophotometrically measured using acetylthiocholine iodide (AChI) as substrate and dithiobisnitrobenzoic acid (DTNB) as the coloring agent using different aliquots of the pesticides. acetylthiocholine iodide 57-81 butyrylcholinesterase Homo sapiens 0-14 20021020-3 2006 Cholinesterase was spectrophotometrically measured using acetylthiocholine iodide (AChI) as substrate and dithiobisnitrobenzoic acid (DTNB) as the coloring agent using different aliquots of the pesticides. acetylthiocholine iodide 83-87 butyrylcholinesterase Homo sapiens 0-14 10445039-3 1999 Ethanol (up to 20% by volume) is shown to induce a dramatic reduction of the affinity of acetylcholinesterase for the acetylthiocholine iodide substrate and all the edrophonium chloride, paraoxon ethyl and propidium diiodide inhibitors, with little influence on the rate constants. acetylthiocholine iodide 118-142 Acetylcholine esterase Drosophila melanogaster 89-109 9494556-2 1997 The Ks for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.077 mM in the control system, the value decreased by 14-38% in the DDP treated systems. acetylthiocholine iodide 29-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 64-68 9580877-6 1998 The Michaelis-Menten constant (Ka) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.061 mM in the control system, and this value was increased by 54-67% in the tacrine-treated systems. acetylthiocholine iodide 57-81 acetylcholinesterase Bos taurus 92-96 8902599-4 1996 The Michaelis-Menten constant (Ks) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.123 mM in the control system, and the MTX-treated systems showed a 10-35% decrease in this value. acetylthiocholine iodide 57-81 acetylcholinesterase Camelus dromedarius 92-96 9408582-2 1997 This technique employs acetylthiocholine iodide as the substrate for cholinesterase activity and silver nitrate impregnation of preterminal axons. acetylthiocholine iodide 23-47 butyrylcholinesterase Homo sapiens 69-83 9238521-2 1997 The Michaelis-Menten constant (Ks) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.072 mM in the control system, a value decreased by 38-55% in the sevin treated systems. acetylthiocholine iodide 57-81 acetylcholinesterase Camelus bactrianus 92-96 9020401-3 1997 The Km for the hydrolysis of acetylthiocholine iodide by AChE was found to be 0.0803 mM in the control system, and the value increased by 19-463% in the GA (0.125-1.0 mM) treated systems. acetylthiocholine iodide 29-53 acetylcholinesterase Camelus bactrianus 57-61 8535296-3 1995 The Km for the hydrolysis of acetylthiocholine iodide by AChE was found to be 97 microM in the control system, and the value increased by 16-144% in the mercuric chloride treated systems. acetylthiocholine iodide 29-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 57-61 8813709-4 1996 The Michaelis-Menten constant (Ks) for the hydrolysis of acetylthiocholine iodide (ASCh) by AChE was 0.13 mM in the control system, a value decreased by 30-61% in the MTX treated systems. acetylthiocholine iodide 57-81 acetylcholinesterase (Cartwright blood group) Homo sapiens 92-96 7814085-1 1994 Acetylthiocholine iodide (ATC) as a common substrate in the combined assay of red blood cell cholinesterase (RBC ChE) and butyrylcholinesterase (BuChE) do not provide the accurate individual enzyme activities. acetylthiocholine iodide 0-24 butyrylcholinesterase Homo sapiens 122-143 7814085-1 1994 Acetylthiocholine iodide (ATC) as a common substrate in the combined assay of red blood cell cholinesterase (RBC ChE) and butyrylcholinesterase (BuChE) do not provide the accurate individual enzyme activities. acetylthiocholine iodide 0-24 butyrylcholinesterase Homo sapiens 145-150 7814085-1 1994 Acetylthiocholine iodide (ATC) as a common substrate in the combined assay of red blood cell cholinesterase (RBC ChE) and butyrylcholinesterase (BuChE) do not provide the accurate individual enzyme activities. acetylthiocholine iodide 26-29 butyrylcholinesterase Homo sapiens 122-143 8449554-1 1993 A modified colorimetric method for the estimation of cholinesterase activity has been worked out using two different substrates, acetylthiocholine iodide for total cholinesterase and a specific substrate, butyrylthiocholine iodide for pseudocholinesterase in the same sample. acetylthiocholine iodide 129-153 butyrylcholinesterase Homo sapiens 164-178 8297889-3 1993 The acetylcholinesterase (AchE) stained by enzyme histochemistry using acetylthiocholine iodide as substrate. acetylthiocholine iodide 71-95 acetylcholinesterase Rattus norvegicus 4-24 8297889-3 1993 The acetylcholinesterase (AchE) stained by enzyme histochemistry using acetylthiocholine iodide as substrate. acetylthiocholine iodide 71-95 acetylcholinesterase Rattus norvegicus 26-30 8449554-1 1993 A modified colorimetric method for the estimation of cholinesterase activity has been worked out using two different substrates, acetylthiocholine iodide for total cholinesterase and a specific substrate, butyrylthiocholine iodide for pseudocholinesterase in the same sample. acetylthiocholine iodide 129-153 butyrylcholinesterase Homo sapiens 235-255 8449554-1 1993 A modified colorimetric method for the estimation of cholinesterase activity has been worked out using two different substrates, acetylthiocholine iodide for total cholinesterase and a specific substrate, butyrylthiocholine iodide for pseudocholinesterase in the same sample. acetylthiocholine iodide 129-153 butyrylcholinesterase Homo sapiens 53-67 8449554-2 1993 This is a modification of the method described by Voss and Sachsse (1970) wherein acetylthiocholine iodide was used for both total and pseudo cholinesterase activities. acetylthiocholine iodide 82-106 butyrylcholinesterase Homo sapiens 142-156 8449554-3 1993 The pseudocholinesterase obtained with acetylthiocholine iodide was significantly higher (P < 0.0001) than that with butyrylthiocholine iodide either in whole blood or serum samples. acetylthiocholine iodide 39-63 butyrylcholinesterase Homo sapiens 4-24 8449554-5 1993 It is therefore suggested that butyrylthiocholine iodide and acetylthiocholine iodide may be used to determine pseudocholinesterase and total cholinesterase activities respectively. acetylthiocholine iodide 61-85 butyrylcholinesterase Homo sapiens 111-131 8449554-5 1993 It is therefore suggested that butyrylthiocholine iodide and acetylthiocholine iodide may be used to determine pseudocholinesterase and total cholinesterase activities respectively. acetylthiocholine iodide 61-85 butyrylcholinesterase Homo sapiens 117-131 1906943-3 1991 Optimum conditions for the cerebellar AChE activity were determined with respect to molarity of the buffer, pH, temperature, and concentrations of substrate (acetylthiocholine iodide), activators (NaCl, MgCl2), and thiol indicator (dithiobisnitrobenzoic acid). acetylthiocholine iodide 158-182 acetylcholinesterase (Cartwright blood group) Homo sapiens 38-42 1293431-3 1992 The latter also resembles an AChE enzyme in the human filarial parasite B. malayi which hydrolyzes acetylthiocholine iodide three times faster than butrylthiocholine iodide. acetylthiocholine iodide 99-123 acetylcholinesterase (Cartwright blood group) Homo sapiens 29-33 1628449-3 1992 AchE activity was evaluated according to Ellman"s method using acetylthiocholine iodide as a substrate and tetraisopropyl-pyrophosphoramide, a specific inhibitor of butyrylocholinesterase. acetylthiocholine iodide 63-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-4 3989273-2 1985 Cytochemical demonstration of AChE is based on coupling the hydrolysis of acetylthiocholine iodide to the precipitation of heavy metal salts. acetylthiocholine iodide 74-98 acetylcholinesterase Rattus norvegicus 30-34 6888651-1 1983 Utilizing a colorimetric method with acetylthiocholine iodide (AThCh) as substrate and eserine and ethopropazine as inhibitors, the activities of AThCh-splitting enzymes, acetylcholinesterase (AChE) and non-specific esterase (psi ChE) were determined in different structures of the autonomic nervous system (ANS) from the left and from the right sides of rabbits with experimental allergic neuritis (EAN) and controls. acetylthiocholine iodide 63-68 ACE-1 Oryctolagus cuniculus 171-191 7459300-1 1981 Acetylcholinesterase (AChE) activity in amniotic fluid was assayed directly by a reaction rate method at 30 degrees C using acetylthiocholine iodide as substrate and ethopropazine as a safe "pseudo" cholinesterase inhibitor. acetylthiocholine iodide 124-148 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 6189639-2 1983 Total ChE was measured by using acetylthiocholine iodide and monitoring the color developed after 5,5"-dithiobis(2-nitrobenzoic acid) is added. acetylthiocholine iodide 32-56 butyrylcholinesterase Homo sapiens 6-9 7459300-1 1981 Acetylcholinesterase (AChE) activity in amniotic fluid was assayed directly by a reaction rate method at 30 degrees C using acetylthiocholine iodide as substrate and ethopropazine as a safe "pseudo" cholinesterase inhibitor. acetylthiocholine iodide 124-148 acetylcholinesterase (Cartwright blood group) Homo sapiens 22-26 952194-1 1976 (1) Cholinesterase activity was investigated in some human lymphatic organs (palatine tonsil, "normal" spleen, "bilharzial" spleen, thymus, lymph node and appendix) using GOMORI"S modification of KOELLE and FRIEDENWALD"S thiocholine iodide method, hydrolyzing acetylthiocholine iodide and butyrylthiocholine iodide. acetylthiocholine iodide 260-284 butyrylcholinesterase Homo sapiens 4-18 488119-2 1979 The catalytic concentrations of the pseudocholinesterase of the afflicted members of both families (male and female) varied between 4800 U/l and 10 200 U/o (acetylthiocholine iodide substrate). acetylthiocholine iodide 157-181 butyrylcholinesterase Homo sapiens 36-56