PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
19647335-3	2010	Antioxidant enzyme activity (superoxide dismutase, SOD; ascorbate peroxidase, APX; peroxidase, POX; glutathione peroxidase, GSH-Px) was significantly increased by the nitrophenolate spray.	2-nitrophenol	167-181	peroxidase 13-like	Gossypium hirsutum	66-76
20141152-8	2010	We then present the integration of the technique into a self-contained hand-held device and demonstrate detection of chemical toxins (2-nitrophenol and 2,4,6-trichlorophenol) in tap water, with no sample preparation steps.	2-nitrophenol	134-147	nuclear RNA export factor 1	Homo sapiens	178-181
19647335-3	2010	Antioxidant enzyme activity (superoxide dismutase, SOD; ascorbate peroxidase, APX; peroxidase, POX; glutathione peroxidase, GSH-Px) was significantly increased by the nitrophenolate spray.	2-nitrophenol	167-181	peroxidase 13-like	Gossypium hirsutum	83-93
19647335-3	2010	Antioxidant enzyme activity (superoxide dismutase, SOD; ascorbate peroxidase, APX; peroxidase, POX; glutathione peroxidase, GSH-Px) was significantly increased by the nitrophenolate spray.	2-nitrophenol	167-181	peroxidase 13-like	Gossypium hirsutum	95-98
19647335-3	2010	Antioxidant enzyme activity (superoxide dismutase, SOD; ascorbate peroxidase, APX; peroxidase, POX; glutathione peroxidase, GSH-Px) was significantly increased by the nitrophenolate spray.	2-nitrophenol	167-181	peroxidase 13-like	Gossypium hirsutum	83-93
20027144-11	2009	CONCLUSION: The results found in this study, the first report on the metabolism of 2-NP by rat hepatic microsomes and rat CYP enzymes, demonstrate that CYP2E1 is the major enzyme oxidizing this compound in rat liver.	2-nitrophenol	83-87	cytochrome P450, family 2, subfamily e, polypeptide 1	Rattus norvegicus	152-158
21591161-3	2008	The substrate for the continuous assay of beta-galactosidase is the chromogenic 2-nitrophenyl-beta-D-galactopyranoside that produces 2-NP.	2-nitrophenol	133-137	galactosidase beta 1	Homo sapiens	42-60
17909483-2	2007	Among compounds tested, the 2-nitrophenol derivative 5c was found to bind satisfactorily to both estrogen receptor subtypes (RBAalpha=5.17 and RBAbeta=3.27).	2-nitrophenol	28-41	estrogen receptor 1	Homo sapiens	97-114
12814972-3	2003	Recombinant CYP3A4 and CYP3A5 (rCYP3A4 and rCYP3A5) both produced 1-OH and 4-OH metabolites from midazolam and triazolam, 6 beta-hydroxytestosterone from testosterone, and oxidized nifedipine from nifedipine.	2-nitrophenol	66-70	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	12-18
16739972-2	2006	The well-known beta-gal substrate analog, o-nitrophenyl beta-d-galactopyranoside, yields the visibly colored, o-nitrophenol product upon hydrolysis, whereas the substrate, p-aminophenyl beta-D-galactopyranoside, gives rise to an electrooxidizable product, p-aminophenol.	2-nitrophenol	110-123	galactosidase beta 1	Homo sapiens	15-23
15948039-4	2005	Periodically, the expression of beta-galactosidase in the cells was measured quantitatively using an enzymatic assay for the conversion of o-nitrophenyl-beta-D: -galactopyranoside (ONPG) to o-nitrophenol (ONP).	2-nitrophenol	190-203	galactosidase, beta 1	Mus musculus	32-50
15948039-4	2005	Periodically, the expression of beta-galactosidase in the cells was measured quantitatively using an enzymatic assay for the conversion of o-nitrophenyl-beta-D: -galactopyranoside (ONPG) to o-nitrophenol (ONP).	2-nitrophenol	181-184	galactosidase, beta 1	Mus musculus	32-50
17166882-7	2007	Comparison of the metabolite profile in BNF-induced mice suggested that CYP1A1 primarily generates 1-OH, 2-OH and (5 + 6)-OH-DBC, whereas CYP1A2 generates primarily (5 + 6)-OH-DBC and CYP1B1 primarily generates 4-OH-DBC.	2-nitrophenol	99-103	cytochrome P450, family 1, subfamily a, polypeptide 1	Mus musculus	72-78
15502008-7	2005	UGT1A8 was most active toward the 1-OH, 4-OH, 5-OH, 6-OH, 7-OH, 10-OH, 11-OH, and 12-OH derivatives of benzo[a]pyrene.	2-nitrophenol	34-38	UDP glucuronosyltransferase family 1 member A8	Rattus norvegicus	0-6
12814972-3	2003	Recombinant CYP3A4 and CYP3A5 (rCYP3A4 and rCYP3A5) both produced 1-OH and 4-OH metabolites from midazolam and triazolam, 6 beta-hydroxytestosterone from testosterone, and oxidized nifedipine from nifedipine.	2-nitrophenol	66-70	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	23-29
1917904-1	1991	Salicylate hydroxylase [EC 1.14.13.1] from Pseudomonas putida catalyzes the hydroxylation of salicylate, and also o-aminophenol, o-nitrophenol, and o-halogenophenols, to catechol.	2-nitrophenol	129-142	salicylate hydroxylase	Pseudomonas putida	0-22
12523509-3	2002	The maximum uptake capacity of live anaerobic granular sludge was found to b e 1,427, 1,511 and 1,865 microg g(-1) VSS for 2-NP, 4-NP and 2,4-DNP, respectively.	2-nitrophenol	123-127	small nucleolar RNA, H/ACA box 73A	Homo sapiens	77-97
11587480-6	2001	Midazolam 1-OH formation exhibited a rank order correlation with increased CYP3A4 protein, whereas [3H]-digoxin transport (a measure of P-gp activity) was unchanged with induction.	2-nitrophenol	10-14	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	75-81
11355194-1	2001	The fast gas-phase reaction of NO3 radicals with phenol was found to yield 2-nitrophenol as the only relevant nitration product.	2-nitrophenol	75-88	NBL1, DAN family BMP antagonist	Homo sapiens	31-34
9065747-6	1997	Cells expressing human CYP1A2 metabolized THA to form its 1-OH derivative (Vmax = 9.36 +/- 0.57 pmol min(-1) mg(-1) total protein), whereas no metabolism was observed with the nonexpressing parental cells.	2-nitrophenol	58-62	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	23-29
11679273-2	2001	The sensing scheme was based on the decrease of yellow product, o-nitrophenol, from a colorless substrate, o-nitrophenyl acetate, due to the inhibition by organophosphorus compounds on AChE.	2-nitrophenol	64-77	acetylcholinesterase (Cartwright blood group)	Homo sapiens	185-189
32870649-7	2020	As Ho doped in the lattices of Zn(O,S), it acts not only to separate photocarriers and to enhance the charge transfer but also to shorten the diffusing time of nitrophenolate ions to catalyst surfaces for further PHR process.	2-nitrophenol	160-174	MYC binding protein 2	Homo sapiens	213-216
1864847-0	1991	Hydroxylation of o-halogenophenol and o-nitrophenol by salicylate hydroxylase.	2-nitrophenol	38-51	salicylate hydroxylase	Pseudomonas putida	55-77
3995052-1	1985	The inhibition of human carbonic anhydrase II (carbonate hydro-lyase, EC 4.2.1.1) by tetrazole, 1,2,4-triazole, 2-nitrophenol, and chloral hydrate has been investigated.	2-nitrophenol	112-125	carbonic anhydrase 2	Homo sapiens	24-45
14904666-2	1951	Effect of ortho-nitrophenol, meta-nitrophenol and para-nitrophenol on blood catalase].	2-nitrophenol	10-27	catalase	Homo sapiens	76-85
25590378-13	2015	CYP3A5*1 carriers had increased 1-OH/4-OH MDZ formation versus homozygous *3 carriers (mean: 2.36 (95% CI:1.11-3.40) vs 0.88 (95% CI:0.48-1.27); p < 0.05).	2-nitrophenol	32-36	cytochrome P450 family 3 subfamily A member 5	Homo sapiens	0-6
30253836-4	2018	The electrochemical results reveal that both the peak currents of m-nitrophenol (m-NP) and p-nitrophenol (p-NP) increased with the increasing of the layer number of the assembled pillar [5]arene, whereas the peak current of o-nitrophenol (o-NP) decreased with the increased layers, which demonstrated an efficient route for discriminating the nitrophenol isomers.	2-nitrophenol	224-237	purine nucleoside phosphorylase	Homo sapiens	106-110
30253836-4	2018	The electrochemical results reveal that both the peak currents of m-nitrophenol (m-NP) and p-nitrophenol (p-NP) increased with the increasing of the layer number of the assembled pillar [5]arene, whereas the peak current of o-nitrophenol (o-NP) decreased with the increased layers, which demonstrated an efficient route for discriminating the nitrophenol isomers.	2-nitrophenol	239-243	purine nucleoside phosphorylase	Homo sapiens	106-110
25796533-2	2015	But also a dye-decolorizing peroxidase of Auricularia auricula-judae (AauDyP) was found to be capable of acting on (i) ortho-nitrophenol (oNP), (ii) meta-nitrophenol (mNP) and (iii) para-nitrophenol (pNP).	2-nitrophenol	119-136	modifier of Niemann Pick type C1	Mus musculus	167-170
25796533-2	2015	But also a dye-decolorizing peroxidase of Auricularia auricula-judae (AauDyP) was found to be capable of acting on (i) ortho-nitrophenol (oNP), (ii) meta-nitrophenol (mNP) and (iii) para-nitrophenol (pNP).	2-nitrophenol	138-141	modifier of Niemann Pick type C1	Mus musculus	167-170
30124645-5	2018	Release of ortho-nitrophenol following the hydrolytic cleavage of ONPG by lactase is measured by a change in absorbance at 420 nm, and the effect of the temperature on the enzymatic reaction is evaluated by carrying out the reaction on ice, at room temperature and at 37  C. More advanced analysis can be implemented using this protocol by assessing the enzyme activity under different conditions and using different reagents.	2-nitrophenol	11-28	lactase	Homo sapiens	74-81
25127101-3	2014	We identified the ortho-nitrophenol as a good scaffold for glucagon receptor inhibitory activity.	2-nitrophenol	18-35	glucagon receptor	Homo sapiens	59-76