PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
3360773-1	1988	An accumulation of Man9,8-GlcNAc2-Asn species is indicative of an impaired N-glycan trimming in undifferentiated cells.	n-glycan	75-83	mannosidase alpha class 1A member 1	Homo sapiens	19-23
2526734-8	1989	Under these conditions the biosynthesis of the N-glycan on leukosialin was completely arrested in an endoglycosidase-H-sensitive step of processing, whereas the O-glycans already contained galactose and sialic acid although at a reduced level.	n-glycan	47-55	LOC105369247	Homo sapiens	59-70
34015111-9	2022	Altered N-glycan profiles of anti-beta2GPI IgG enables enabled the antibodies with proinflammatory properties.	n-glycan	8-16	apolipoprotein H	Homo sapiens	34-42
33756033-5	2021	Each IL-6 glycoform was tested in three animals and reproducibly showed individual serum clearances depending on the structure of the N-glycan.	n-glycan	134-142	interleukin 6	Rattus norvegicus	5-9
33937725-5	2021	Neutralization mechanism of these antibodies involves receptors other than the canonical hACE2 on target cells, relying both on amino-acid and N-glycan epitope-recognition, suggesting alternative viral cellular-portals.	n-glycan	143-151	angiotensin converting enzyme 2	Homo sapiens	89-94
33996901-7	2021	Interestingly, Siglec-10 exhibited dramatic binding divergence toward a pair of Neu5Ac-containing asymmetric N-glycan isomers, as well as their Neu5Gc-containing counterparts.	n-glycan	109-117	sialic acid binding Ig like lectin 10	Homo sapiens	15-24
34000456-5	2021	In paclitaxel (PTX) resistant MCF7 cells, 19 differentially expressed N-glycan-related proteins were identified, of which MGAT4A was the most significantly down-regulated, consistent with decrease in MGAT4A expression at mRNA level in PTX treated BC cells.	n-glycan	70-78	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	122-128
33544829-0	2021	N-glycan mediated shielding of ADAMTS13 prevents binding of pathogenic autoantibodies in immune-mediated TTP.	n-glycan	0-8	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	31-39
33544829-7	2021	One N-glycan variant (NGLY3-ADAMTS13, containing a K608N substitution) showed strongly reduced reactivity with TTP patient sera (28%) as compared to WT-ADAMTS13 (100%).	n-glycan	4-12	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	28-36
33544829-7	2021	One N-glycan variant (NGLY3-ADAMTS13, containing a K608N substitution) showed strongly reduced reactivity with TTP patient sera (28%) as compared to WT-ADAMTS13 (100%).	n-glycan	4-12	ADAM metallopeptidase with thrombospondin type 1 motif 13	Homo sapiens	152-160
33650863-4	2021	In total, 212 N-glycan compositions were identified from the purified UMOD, and 17% were high-mannose glycans, 2% were afucosylated/asialylated, 3% were neutral fucosylated, 28% were sialylated (with no fucose), 46% were fucosylated and sialylated, and 4% were sulfated.	n-glycan	14-22	uromodulin	Homo sapiens	70-74
33650863-6	2021	To our knowledge, this is the first study to perform comprehensive N-glycan profiling of UMOD using nanoLC-MS/MS.	n-glycan	67-75	uromodulin	Homo sapiens	89-93
33471394-0	2021	Novel erythropoietin-based therapeutic candidates with extra N-glycan sites that block hematopoiesis but preserve neuroplasticity.	n-glycan	61-69	erythropoietin	Homo sapiens	6-20
33734311-2	2021	Previous studies using free N-glycans as acceptor substrates indicated that a terminal beta1,2-GlcNAc moiety on the Man-alpha1,3-Man arm of N-glycan substrates is required for efficient FUT8-catalyzed core-fucosylation.	n-glycan	28-36	fucosyltransferase 8	Homo sapiens	186-190
33788965-5	2021	Biochemical and electrophysiological studies revealed that N-glycan acquisition on CALHM1 and 3, respectively, controls the biosynthesis and gating kinetics of the CALHM1/3 channel.	n-glycan	59-67	calcium homeostasis modulator 1	Homo sapiens	83-95
33788965-5	2021	Biochemical and electrophysiological studies revealed that N-glycan acquisition on CALHM1 and 3, respectively, controls the biosynthesis and gating kinetics of the CALHM1/3 channel.	n-glycan	59-67	calcium homeostasis modulator 1	Homo sapiens	164-172
33202418-2	2021	Site-directed mutagenesis in the N-glycan binding domain (GBD)abolishes the ability of mutant CALRto oncogenically activate the thrombopoietin receptor (MPL).We thus hypothesized that a small molecule targeting the GBD might inhibit the oncogenicity of the mutant CALR.	n-glycan	33-41	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	128-151
33853474-3	2021	In fact, WLS was discovered to integrate a protein complex in N-glycan-dependent and WLS domain-selective manners, comprising ER stress sensors and lectin chaperones.	n-glycan	62-70	wntless WNT ligand secretion mediator	Mus musculus	9-12
33883138-0	2021	Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver.	n-glycan	47-55	nuclear receptor subfamily 1 group H member 4	Homo sapiens	18-21
33883138-0	2021	Nuclear receptors FXR and SHP regulate protein N-glycan modifications in the liver.	n-glycan	47-55	nuclear receptor subfamily 0 group B member 2	Homo sapiens	26-29
33202418-2	2021	Site-directed mutagenesis in the N-glycan binding domain (GBD)abolishes the ability of mutant CALRto oncogenically activate the thrombopoietin receptor (MPL).We thus hypothesized that a small molecule targeting the GBD might inhibit the oncogenicity of the mutant CALR.	n-glycan	33-41	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	153-156
33202418-2	2021	Site-directed mutagenesis in the N-glycan binding domain (GBD)abolishes the ability of mutant CALRto oncogenically activate the thrombopoietin receptor (MPL).We thus hypothesized that a small molecule targeting the GBD might inhibit the oncogenicity of the mutant CALR.	n-glycan	33-41	calreticulin	Homo sapiens	94-98
33644825-6	2021	Comparing it to control samples, we have observed Tf under-occupancy of glycosylation site(s) typical of a defective N-glycan assembly and the occurrence of oligomannose and hybrid type N-glycans.	n-glycan	117-125	transferrin	Homo sapiens	50-52
33752328-0	2021	Specific Analysis of alpha-2,3-Sialylated N-Glycan Linkage Isomers by Microchip Capillary Electrophoresis-Mass Spectrometry.	n-glycan	42-50	glycoprotein hormone subunit alpha 2	Homo sapiens	21-28
33752328-1	2021	Sialylated N-glycan isomers with alpha-2,3 and alpha-2,6 linkages play crucial and distinctive roles in diverse physiological and pathological processes.	n-glycan	11-19	glycoprotein hormone subunit alpha 2	Homo sapiens	33-40
33752328-1	2021	Sialylated N-glycan isomers with alpha-2,3 and alpha-2,6 linkages play crucial and distinctive roles in diverse physiological and pathological processes.	n-glycan	11-19	glycoprotein hormone subunit alpha 2	Homo sapiens	47-54
33752328-3	2021	However, the specific analysis of alpha-2,3-sialylated N-glycan linkage isomers remains challenging due to their extremely low abundance and technical limitations in separation and detection.	n-glycan	55-63	glycoprotein hormone subunit alpha 2	Homo sapiens	34-41
33752328-4	2021	Herein, we designed an integrated strategy that combines linkage-specific derivatization and a charge-sensitive separation method based on microfluidic chip capillary electrophoresis-mass spectrometry (microchip CE-MS) for specific analysis of alpha-2,3-sialylated N-glycan linkage isomers for the first time.	n-glycan	265-273	glycoprotein hormone subunit alpha 2	Homo sapiens	244-251
33869084-11	2021	Further metabolic pathway analysis showed 7 predictive functional profiles, including glycosphingolipid biosynthesis, oxidative phosphorylation, and N-glycan biosynthesis were enriched in IgAN.	n-glycan	149-157	IGAN1	Homo sapiens	188-192
33644825-10	2021	This preliminary work aims at considering serum N-glycan accumulation of high mannosylated glycoforms, such as oligomannose and hybrid type N-glycans, as potential diagnostic signals for ALG2-CDG patients.	n-glycan	48-56	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	187-191
33314123-10	2021	Additional results show inhibiting NEU activity significantly increases sialic acid-containing N-glycan levels.	n-glycan	95-103	neuraminidase 1	Mus musculus	35-38
33657316-1	2021	The heterogeneity associated with glycosylation of the 66 N-glycan sites on the protein trimer making up the spike (S) region of the SARS-CoV-2 virus has been assessed by charge detection mass spectrometry (CDMS).	n-glycan	58-66	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	109-114
33551170-1	2021	In bovine milk serum, the whey proteins with the highest N-glycan contribution are lactoferrin, IgG, and glycosylation-dependent cellular adhesion molecule 1 (GlyCAM-1); GlyCAM-1 is the dominant N-linked glycoprotein in bovine whey protein products.	n-glycan	57-65	lactotransferrin	Bos taurus	83-94
33551170-1	2021	In bovine milk serum, the whey proteins with the highest N-glycan contribution are lactoferrin, IgG, and glycosylation-dependent cellular adhesion molecule 1 (GlyCAM-1); GlyCAM-1 is the dominant N-linked glycoprotein in bovine whey protein products.	n-glycan	57-65	glycosylation dependent cell adhesion molecule 1	Bos taurus	170-178
33551170-7	2021	Overall, approximately 60% of the N-glycan pool in milk protein was sialylated, or fucosylated, or both; GlyCAM-1 contributed approximately 78% of the total number of glycans in the overall whey protein N-linked glycan pool.	n-glycan	34-42	casein beta	Bos taurus	51-63
33729545-0	2021	N-glycan fingerprint predicts alpha-fetoprotein negative hepatocellular carcinoma: a large-scale multicenter study.	n-glycan	0-8	alpha fetoprotein	Homo sapiens	30-47
33729545-12	2021	In conclusion, the biomarker panel consisting of 13 N-glycan structures abundances using the best-performing algorithm (LR) was defined and indicative as an effective tool for HCC prediction and prognosis estimate in AFP negative subjects.	n-glycan	52-60	alpha fetoprotein	Homo sapiens	217-220
33157282-7	2021	N-glycan analysis of in vitro and in vivo expression of EPO-Fc modified by GnT-IVa (EPO-Fc/GnT-IVa) showed an increase in high molecular weight structures, which corresponded to tri- and tetra-antennary N-glycans in SiHa cells and mostly tri-antennary N-glycans in goat s milk from transformed mammary tissue.	n-glycan	0-8	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	75-82
33157282-7	2021	N-glycan analysis of in vitro and in vivo expression of EPO-Fc modified by GnT-IVa (EPO-Fc/GnT-IVa) showed an increase in high molecular weight structures, which corresponded to tri- and tetra-antennary N-glycans in SiHa cells and mostly tri-antennary N-glycans in goat s milk from transformed mammary tissue.	n-glycan	0-8	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	84-98
33727664-4	2021	Here we show that N-glycan from pathogenic C. albicans ameliorates mouse sepsis through immunosuppressive cytokine IL-10.	n-glycan	18-26	interleukin 10	Mus musculus	115-120
33727664-5	2021	In a sepsis model using lipopolysaccharide (LPS), injection of the N-glycan upregulated serum IL-10, and suppressed pro-inflammatory IL-1beta, TNF-alpha and IFN-gamma.	n-glycan	67-75	interleukin 10	Mus musculus	94-99
33727664-8	2021	Knocking out the C-type lectin Dectin-2 abrogated the N-glycan-mediated IL-10 augmentation.	n-glycan	54-62	interleukin 10	Mus musculus	72-77
33577335-6	2021	Further surface plasmon resonance (SPR) and hydrogen/deuterium exchange mass spectroscopic experiments confirm that the evaluated complex type N-glycan impedes the binding between IL-17A and its receptor IL-17RA.	n-glycan	143-151	interleukin 17A	Homo sapiens	180-186
33750826-3	2021	Here, focusing on insect N-glycosylation, we characterized Bombyx mori N-acetylgalactosaminyltransferase (BmGalNAcT) participating in complex N-glycan biosynthesis in mammals.	n-glycan	142-150	N-acetylgalactosaminyltransferase 7	Bombyx mori	106-115
32858386-5	2021	Twenty-three alpha2,6-linked sialylated N-glycan isomers were detected with no alpha2,3-linked isomer observed.	n-glycan	40-48	immunoglobulin kappa variable 6-21 (non-functional)	Homo sapiens	13-21
33629527-3	2021	The influenza A virus (IAV) proteins hemagglutinin (HA) and neuraminidase (NA) have multiple N-glycosylation sites, and alteration of N-glycan micro- and macroheterogeneity can have strong effects on virulence and immunogenicity.	n-glycan	134-142	neuraminidase 1	Homo sapiens	60-73
33577335-0	2021	Probing N-Glycan Functions in Human Interleukin-17A Based on Chemically Synthesized Homogeneous Glycoforms.	n-glycan	8-16	interleukin 17A	Homo sapiens	36-51
33577335-6	2021	Further surface plasmon resonance (SPR) and hydrogen/deuterium exchange mass spectroscopic experiments confirm that the evaluated complex type N-glycan impedes the binding between IL-17A and its receptor IL-17RA.	n-glycan	143-151	interleukin 17 receptor A	Homo sapiens	204-211
33476097-0	2021	Identification and Characterization of a Residual Host Cell Protein Hexosaminidase B Associated with N-glycan Degradation During the Stability Study of a Therapeutic Recombinant Monoclonal Antibody Product.	n-glycan	101-109	hexosaminidase subunit beta	Homo sapiens	68-84
33583022-6	2021	This spectrum of N-glycan changes is unique to ALG3-CDG.	n-glycan	17-25	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	47-51
33090600-3	2021	This is mediated by the interaction of Lewis type glycan structures on the N-glycan of MOG to the DC-SIGN receptor on dendritic cells (DCs).	n-glycan	75-83	myelin oligodendrocyte glycoprotein	Homo sapiens	87-90
33376510-0	2021	Silencing GnT-V reduces oxaliplatin chemosensitivity in human colorectal cancer cells through N-glycan alteration of organic cation transporter member 2.	n-glycan	94-102	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	10-15
33376510-0	2021	Silencing GnT-V reduces oxaliplatin chemosensitivity in human colorectal cancer cells through N-glycan alteration of organic cation transporter member 2.	n-glycan	94-102	solute carrier family 22 member 2	Homo sapiens	117-152
33376528-12	2021	Pathway enrichment analysis suggested that P4HB was involved in protein processing in the endoplasmic reticulum (ER), including N-glycan modification and protein metabolic processes responding to ER stress.	n-glycan	128-136	prolyl 4-hydroxylase subunit beta	Homo sapiens	43-47
33389473-9	2021	The molecular dynamics simulation analysis shows that the p.Ser633Trp mutation on the alpha-L-iduronidase affect significant the temporal and spatial properties of the different structural loops, the N-glycan attached to Asn372 and amino acid residues around the catalytic site of this enzyme.	n-glycan	200-208	alpha-L-iduronidase	Homo sapiens	86-105
33679849-9	2021	Especially in gntI mutant seedlings, the early block of complex N-glycan formation resulted in an increased auxin sensitivity.	n-glycan	64-72	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	14-18
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	n-glycan	145-153	immunoglobulin heavy constant epsilon	Homo sapiens	24-27
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	n-glycan	145-153	allergen Ara h 1, clone P17	Arachis hypogaea	36-43
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	n-glycan	145-153	allergen Ara h 1, clone P17	Arachis hypogaea	157-164
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	n-glycan	145-153	allergen Ara h 1, clone P17	Arachis hypogaea	157-164
33439436-8	2021	The cross-reactivity of IgE against Ara h 1 in the serum of one peanut allergy patient was completely lost by de-N-glycosylation, indicating the N-glycan of Ara h 1 was the sole epitope for the Ara h 1- specific IgE in the patient.	n-glycan	145-153	immunoglobulin heavy constant epsilon	Homo sapiens	212-215
33245474-4	2021	Expression plasmids encoding SARS-CoV-2 spike (S) and human ACE2 glycoproteins (GP) were tested to evaluate N-glycan modifications induced by alpha-glucosidase inhibition.	n-glycan	108-116	sucrase-isomaltase	Homo sapiens	142-159
33177111-7	2021	Detailed analyses of N- and O-linked oligosaccharides of CD55 released from scramble or ST3GAL1 siRNA-treated breast cancer cells by tandem mass spectrometry revealed that the N-glycan profile was not affected by ST3GAL1 silencing.	n-glycan	176-184	CD55 molecule (Cromer blood group)	Homo sapiens	57-61
33460651-6	2021	Here, using soluble, recombinant human Gb3/CD77 synthase and p.Q211E mutein, we demonstrate that both enzymes can synthesize the P1 glycotope (terminal Galalpha1 4Galbeta1 4GlcNAc-R) on a complex type N-glycan and a synthetic N-glycoprotein (saposin D).	n-glycan	201-209	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	39-42
33460651-6	2021	Here, using soluble, recombinant human Gb3/CD77 synthase and p.Q211E mutein, we demonstrate that both enzymes can synthesize the P1 glycotope (terminal Galalpha1 4Galbeta1 4GlcNAc-R) on a complex type N-glycan and a synthetic N-glycoprotein (saposin D).	n-glycan	201-209	alpha 1,4-galactosyltransferase (P blood group)	Homo sapiens	43-56
33479349-6	2021	In particular, AT-1 sTg animals displayed a marked delay in Golgi-to-plasma membrane protein trafficking, significant alterations in Golgi-based N-glycan modification, and a marked expansion of the lysosomal network.	n-glycan	145-153	chromosome 6 open reading frame 15	Homo sapiens	20-23
33440845-6	2021	N-glycan analysis with mass spectrometry indeed demonstrated heterogeneous glycosylation for recombinant C1-INH containing terminal galactose and terminal sialic acid.	n-glycan	0-8	serpin family G member 1	Homo sapiens	105-111
33374805-0	2020	Discovery and Biological Evaluation of CD147 N-Glycan Inhibitors: A New Direction in the Treatment of Tumor Metastasis.	n-glycan	45-53	basigin (Ok blood group)	Homo sapiens	39-44
33383793-0	2020	N-Glycan Modifications with Negative Charge in a Natural Polymer Mucin from Bovine Submaxillary Glands, and Their Structural Role.	n-glycan	0-8	mucin 1, cell surface associated	Bos taurus	65-70
32985191-2	2020	To demonstrate the accessibility toward a ubiquitinated glycoprotein probe for the study of glycoprotein degradation by UPS, we synthesized ubiquitinated glycoprotein CC motif chemokine 1 (CCL1) bearing a high-mannose type N-glycan, starting from six peptide segments.	n-glycan	223-231	C-C motif chemokine ligand 1	Homo sapiens	189-193
33310702-4	2021	These observations indicate that specifically manipulating CD16a N-glycan composition in CD16a-expressing effector cells including NK cells may improve treatment efficacy.	n-glycan	65-73	Fc gamma receptor IIIa	Homo sapiens	59-64
33453988-4	2020	Here we report that GlcNAc and N-glycan branching trigger oligodendrogenesis from precursor cells by inhibiting platelet-derived growth factor receptor-alpha cell endocytosis.	n-glycan	31-39	platelet derived growth factor receptor, alpha polypeptide	Mus musculus	112-157
32985191-4	2020	CCL1 glycopeptide with a high-mannose-type N-glycan as well as a delta-thioLys residue was synthesized chemically.	n-glycan	43-51	C-C motif chemokine ligand 1	Homo sapiens	0-4
33310702-4	2021	These observations indicate that specifically manipulating CD16a N-glycan composition in CD16a-expressing effector cells including NK cells may improve treatment efficacy.	n-glycan	65-73	Fc gamma receptor IIIa	Homo sapiens	89-94
33310702-5	2021	However, it is unclear if modifying the expression of select genes that encode processing enzymes in CD16a-expressing effector cells is sufficient to affect N-glycan composition.	n-glycan	157-165	Fc gamma receptor IIIa	Homo sapiens	101-106
33310702-9	2021	N-glycan processing correlated with the expression of glycan modifying genes and thus explained the substantial differences in CD16a processing by NK cells of different origins.	n-glycan	0-8	Fc gamma receptor IIIa	Homo sapiens	127-132
33262181-2	2020	Inhibiting N-glycan stabilization of B7-H4 generates an immune hot cancer that is more responsive to combination therapies.See related article by Song et al., p. 1872.	n-glycan	11-19	V-set domain containing T cell activation inhibitor 1	Mus musculus	37-42
32524825-9	2020	Mechanistically, SELENOT is anchored to the ER membrane and is able to bind the STT3A-type oligosaccharyltransferase complex in order to regulate N-glycan occupancy of specific substrates including glycohormones and GPI-anchored proteins which have key roles in cell adhesion and communication.	n-glycan	146-154	selenoprotein T	Homo sapiens	17-24
32779579-2	2020	Our previous study using N-glycan-manipulated cell lines demonstrated that defects in N-glycans or decreased beta1,6GlcNAc-branched N-glycans on beta4 integrin suppress beta4 integrin-mediated cancer cell adhesion, migration, invasion, and tumorigenesis.	n-glycan	25-33	BCL2 related protein A1	Homo sapiens	109-114
33231436-0	2020	Chemical Synthesis of an Erythropoietin Glycoform Having a Triantennary N-Glycan: Significant Change of Biological Activity of Glycoprotein by Addition of a Small Molecular Weight Trisaccharide.	n-glycan	72-80	erythropoietin	Mus musculus	25-39
33273096-3	2020	We show that microRNA-223 (miR-223)-mediated regulation of N-glycan biosynthesis in endothelial cells (ECs) regulates EHT.	n-glycan	59-67	microRNA 223	Homo sapiens	13-25
33273096-3	2020	We show that microRNA-223 (miR-223)-mediated regulation of N-glycan biosynthesis in endothelial cells (ECs) regulates EHT.	n-glycan	59-67	microRNA 223	Homo sapiens	27-34
33273096-7	2020	EC-specific expression of an N-glycan Adam10 mutant or of the N-glycoenzymes phenocopied miR-223 mutant defects.	n-glycan	29-37	ADAM metallopeptidase domain 10	Homo sapiens	38-44
33273096-7	2020	EC-specific expression of an N-glycan Adam10 mutant or of the N-glycoenzymes phenocopied miR-223 mutant defects.	n-glycan	29-37	microRNA 223	Homo sapiens	89-96
32938718-6	2020	However, in SLC35A3-knock-out CHO cells, only limited changes were observed - GlcNAc was still incorporated into N-glycans but complex type N-glycan branching was impaired, although UDP-GlcNAc transport into Golgi vesicles was not decreased.	n-glycan	113-121	UDP-N-acetylglucosamine transporter	Cricetulus griseus	12-19
33125131-8	2020	N-glycan profiles were found to differ between the highly invasive liver cancer cell line HLE and the less invasive cell line HepG2.	n-glycan	0-8	elastase, neutrophil expressed	Homo sapiens	90-93
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	elastase, neutrophil expressed	Homo sapiens	87-90
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	elastase, neutrophil expressed	Homo sapiens	102-105
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	plasminogen activator, urokinase	Homo sapiens	110-113
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	elastase, neutrophil expressed	Homo sapiens	102-105
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	plasminogen activator, urokinase	Homo sapiens	139-142
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	elastase, neutrophil expressed	Homo sapiens	102-105
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	177-182
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	elastase, neutrophil expressed	Homo sapiens	102-105
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	4-12	plasminogen activator, urokinase	Homo sapiens	139-142
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	41-49	plasminogen activator, urokinase	Homo sapiens	110-113
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	41-49	plasminogen activator, urokinase	Homo sapiens	139-142
33125131-12	2020	One N-glycan (m/z=1892) was common among N-glycans in the comparative analysis between HLE and HepG2, HLE and uPA knockdown HLE, HepG2 and uPA-overexpressing HepG2, and HLE and GnT-V knockdown HLE cells and among N-glycan profiles in human uPA.	n-glycan	41-49	plasminogen activator, urokinase	Homo sapiens	139-142
33125131-13	2020	Therefore, N-glycosylation is an important factor controlling invasiveness of liver cancer cells, and a specific N-glycan (m/z=1892) associated with the invasion of liver cancer cells via uPA was identified in the present study.	n-glycan	113-121	plasminogen activator, urokinase	Homo sapiens	188-191
32967966-3	2020	By directly binding the N-glycan on proteins, calnexin was observed to efficiently retain GPI-APs in the ER until they were correctly folded.	n-glycan	24-32	calnexin	Homo sapiens	46-54
32967966-3	2020	By directly binding the N-glycan on proteins, calnexin was observed to efficiently retain GPI-APs in the ER until they were correctly folded.	n-glycan	24-32	epiregulin	Homo sapiens	105-107
32938718-9	2020	In CHO and HEK293T cells the effect of SLC35A3 deficiency on N-glycan branching was potentiated in the absence of SLC35A2.	n-glycan	61-69	solute carrier family 35 member A3	Homo sapiens	39-46
33281853-8	2020	The purified soluble SSExt mIFNgamma(SP)10 protein was glycosylated with abundant complex-type N-glycan attached to residues N56 and N128, and exhibited biological activity against Sindbis virus and Influenza virus replication in human cell culture systems.	n-glycan	95-103	acrosomal vesicle protein 1	Homo sapiens	21-42
33154157-3	2020	Endo-alpha-1,2-mannosidase (MANEA) is the sole endo-acting glycoside hydrolase involved in N-glycan trimming and is located within the Golgi, where it allows ER-escaped glycoproteins to bypass the classical N-glycosylation trimming pathway involving ER glucosidases I and II.	n-glycan	91-99	mannosidase endo-alpha	Homo sapiens	28-33
32723834-7	2020	RESULTS: We identified MAN2A1, encoding an enzyme in N-glycan maturation, as a key immunomodulatory gene.	n-glycan	53-61	mannosidase alpha class 2A member 1	Homo sapiens	23-29
33045166-1	2020	We report herein an efficient chemical synthesis of homogeneous human E-cadherin N-linked glycopeptides consisting of a heptapeptide sequence adjacent to the Asn-633 N-glycosylation site with representative N-glycan structures, including a conserved trisaccharide, a core-fucosylated tetrasaccharide, and a complex-type biantennary octasaccharide.	n-glycan	207-215	cadherin 1	Homo sapiens	70-80
33064451-7	2020	In addition, we compared N-glycan profiles of the recombinant spike proteins produced from different expression systems, including human embryonic kidney (HEK 293) cells and Spodoptera frugiperda (SF9) insect cells.	n-glycan	25-33	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	62-67
33103998-6	2020	Blocking N-glycan biosynthesis at the oligomannose stage using both genetic approaches and the small molecule kifunensine dramatically reduced viral entry into ACE2 expressing HEK293T cells.	n-glycan	9-17	angiotensin converting enzyme 2	Homo sapiens	160-164
32835658-6	2020	With this approach, we identified that alpha2,3-linked N-sialyllactose polymer has significant macrophage modulation activity among the N-glycan polymers tested.	n-glycan	136-144	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	39-47
33103998-9	2020	Among them, inhibition of N-glycan biosynthesis enhanced Spike-protein proteolysis.	n-glycan	26-34	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	57-62
32975931-3	2020	By use of MALDI-MS imaging (MSI) in combination with PNGase F treatment, also spatially correlated N-glycan profiling from tissue sections becomes possible.	n-glycan	99-107	N-glycanase 1	Homo sapiens	53-59
32763972-0	2020	Point Mutations that Inactivate MGAT4D-L, an Inhibitor of MGAT1 and Complex N-Glycan Synthesis.	n-glycan	76-84	MGAT4 family member D	Homo sapiens	32-38
32553951-0	2020	N-glycan in the scavenger receptor cysteine-rich domain of hepsin promotes intracellular trafficking and cell surface expression.	n-glycan	0-8	hepsin	Homo sapiens	59-65
32553951-8	2020	Our results indicate that the N-glycan in the SRCR domain of hepsin promotes intracellular trafficking and cell surface expression, possibly by a calnexin-dependent mechanism in facilitating ER exiting.	n-glycan	30-38	hepsin	Homo sapiens	61-67
32553951-8	2020	Our results indicate that the N-glycan in the SRCR domain of hepsin promotes intracellular trafficking and cell surface expression, possibly by a calnexin-dependent mechanism in facilitating ER exiting.	n-glycan	30-38	calnexin	Homo sapiens	146-154
32897876-7	2020	ZIP8 391-Thr associated with reduced triantennary plasma N-glycan species in a population-based cohort to define a genotype-specific glycophenotype hypothesized to be linked to Mn-dependent glycosyltransferase activity.	n-glycan	57-65	solute carrier family 39 (metal ion transporter), member 8	Mus musculus	0-4
32763972-2	2020	MGAT1 is the GlcNAc-transferase that initiates complex and hybrid N-glycan synthesis.	n-glycan	66-74	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-5
32945502-4	2020	In silico evaluation in each of the CRC consensus molecular subtypes (CMSs) revealed that high expression levels of CLDN3 (gene encoding claudin-3) in CMS2 and CMS3 worsened the patients" long-term survival, whereas a decrease in claudin-3 levels concomitant with a reduction in phosphorylation levels of epidermal growth factor receptor (EGFR) and insulin-like growth factor 1 receptor (IGF1R) could be achieved by inhibiting N-glycan biosynthesis in CRC cells.	n-glycan	427-435	claudin 3	Homo sapiens	116-121
32958677-3	2020	Remarkably, ER mannosidase I/Man1b1, the first alpha-mannosidase implicated in this conventional N-glycan-mediated process, can also contribute to ERAD in an unconventional, catalysis-independent manner.	n-glycan	97-105	mannosidase alpha class 1B member 1	Homo sapiens	29-35
32945502-4	2020	In silico evaluation in each of the CRC consensus molecular subtypes (CMSs) revealed that high expression levels of CLDN3 (gene encoding claudin-3) in CMS2 and CMS3 worsened the patients" long-term survival, whereas a decrease in claudin-3 levels concomitant with a reduction in phosphorylation levels of epidermal growth factor receptor (EGFR) and insulin-like growth factor 1 receptor (IGF1R) could be achieved by inhibiting N-glycan biosynthesis in CRC cells.	n-glycan	427-435	claudin 3	Homo sapiens	137-146
32945502-6	2020	RTKs are modulated by their N-linked glycans, and inhibition of N-glycan biosynthesis decreased the claudin-3 levels; therefore, we evaluated the correlation between N-glycogenes and CLDN3 expression levels in each of the CRC molecular subtypes.	n-glycan	64-72	claudin 3	Homo sapiens	100-109
32855403-5	2020	Loss of N-glycan-binding capability of galectin-9 causes its complete depletion from lysosomes and defective autophagy, leading to increased endoplasmic reticulum (ER) stress preferentially in autophagy-active Paneth cells and acinar cells.	n-glycan	8-16	lectin, galactose binding, soluble 9	Mus musculus	39-49
33010941-4	2021	Another enzyme, one of the N-glycan branching enzymes, beta1,4 N-acetylglucosaminyltransferase III (GnT-III) (the MGAT3 gene) has been reported to suppress EMT.	n-glycan	27-35	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	100-107
33010941-4	2021	Another enzyme, one of the N-glycan branching enzymes, beta1,4 N-acetylglucosaminyltransferase III (GnT-III) (the MGAT3 gene) has been reported to suppress EMT.	n-glycan	27-35	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	114-119
33010941-8	2021	This review mainly focuses on GnT-III, GnT-V and FUT8, major players as N-glycan branching enzymes in cancer in relation to EMT programs, and also discusses the catalytic mechanisms of GnT-V and FUT8 whose crystal structures have now been obtained.	n-glycan	72-80	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	30-37
33010941-8	2021	This review mainly focuses on GnT-III, GnT-V and FUT8, major players as N-glycan branching enzymes in cancer in relation to EMT programs, and also discusses the catalytic mechanisms of GnT-V and FUT8 whose crystal structures have now been obtained.	n-glycan	72-80	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	39-44
33010941-8	2021	This review mainly focuses on GnT-III, GnT-V and FUT8, major players as N-glycan branching enzymes in cancer in relation to EMT programs, and also discusses the catalytic mechanisms of GnT-V and FUT8 whose crystal structures have now been obtained.	n-glycan	72-80	fucosyltransferase 8	Homo sapiens	49-53
32900381-6	2020	For glycoproteins, secreted protein acidic and rich in cysteine (SPARC), which is associated with various lung disorders, such as chronic obstructive pulmonary disease (COPD) and lung cancer, will be taken as an example showing that the core fucosylation of N-glycan in SPARC regulates protein-binding affinity with extracellular matrix collagen.	n-glycan	258-266	secreted protein acidic and cysteine rich	Homo sapiens	19-63
32900381-6	2020	For glycoproteins, secreted protein acidic and rich in cysteine (SPARC), which is associated with various lung disorders, such as chronic obstructive pulmonary disease (COPD) and lung cancer, will be taken as an example showing that the core fucosylation of N-glycan in SPARC regulates protein-binding affinity with extracellular matrix collagen.	n-glycan	258-266	secreted protein acidic and cysteine rich	Homo sapiens	65-70
32904601-6	2021	Refined structural models of HCoV-19 S and hACE2 were built by adding N-glycan and PTMs to recently published cryogenic electron microscopy (cryo-EM) structures.	n-glycan	70-78	angiotensin converting enzyme 2	Homo sapiens	43-48
32745987-4	2020	Here we report that N-glycan branching in B cells dose dependently reduces pro-inflammatory innate responses by titrating decreases in Toll-like receptor-4 (TLR4) and TLR2 surface expression via endocytosis.	n-glycan	20-28	toll-like receptor 4	Mus musculus	135-155
32842538-9	2020	In addition, lack of the N-glycan on prM induced nuclear translocation of CCAAT-enhancer-binding protein homologous protein (CHOP), an ER stress marker.	n-glycan	25-33	DNA damage inducible transcript 3	Homo sapiens	74-123
32842538-9	2020	In addition, lack of the N-glycan on prM induced nuclear translocation of CCAAT-enhancer-binding protein homologous protein (CHOP), an ER stress marker.	n-glycan	25-33	DNA damage inducible transcript 3	Homo sapiens	125-129
32745987-4	2020	Here we report that N-glycan branching in B cells dose dependently reduces pro-inflammatory innate responses by titrating decreases in Toll-like receptor-4 (TLR4) and TLR2 surface expression via endocytosis.	n-glycan	20-28	toll-like receptor 4	Mus musculus	157-161
32745987-4	2020	Here we report that N-glycan branching in B cells dose dependently reduces pro-inflammatory innate responses by titrating decreases in Toll-like receptor-4 (TLR4) and TLR2 surface expression via endocytosis.	n-glycan	20-28	toll-like receptor 2	Mus musculus	167-171
32745987-5	2020	In contrast, a minimal level of N-glycan branching maximizes surface retention of the B cell receptor (BCR) and the CD19 co-receptor to promote adaptive immunity.	n-glycan	32-40	CD19 antigen	Mus musculus	116-120
32707739-8	2020	In conclusion, our findings suggest that these N-glycans have distinct roles in the ER-exit of GluA1 and GluA2 homo-oligomers; N-glycan at GluA1N63 is a prerequisite for GluA1 ER-exit, whereas N-glycans at GluA1N363 and GluA2N370 control the ER-exit rate.	n-glycan	47-55	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	95-100
32348856-0	2020	Glycoengineering tobacco plants to stably express recombinant human erythropoietin with different N-glycan profiles.	n-glycan	98-106	erythropoietin	Homo sapiens	68-82
32348856-5	2020	The human MGAT3 was co-expressed to produce N-glycan chains with bisecting GlcNAc.	n-glycan	44-52	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	10-15
32348856-10	2020	Created transgenic plants expressing EPO and ST/GalT could be used to produce rhuEPO with high proportion of beta1,4-galactose-extended N-glycan chains for tissue protective purposes.	n-glycan	136-144	erythropoietin	Homo sapiens	37-40
32591389-3	2020	During T cell development, N-glycan branching is required for positive selection of thymocytes, inhibiting both death by neglect and negative selection via enhanced surface retention of the CD4/CD8 coreceptors and limiting TCR clustering/signaling, respectively.	n-glycan	27-35	CD4 antigen	Mus musculus	190-193
32591389-10	2020	Together, these data suggest that, as in T cells, N-glycan branching promotes positive selection of B cells by augmenting pre-BCR/BCR signaling via CD19 surface retention, whereas limiting negative selection from excessive BCR engagement.	n-glycan	50-58	CD19 antigen	Mus musculus	148-152
32707739-8	2020	In conclusion, our findings suggest that these N-glycans have distinct roles in the ER-exit of GluA1 and GluA2 homo-oligomers; N-glycan at GluA1N63 is a prerequisite for GluA1 ER-exit, whereas N-glycans at GluA1N363 and GluA2N370 control the ER-exit rate.	n-glycan	47-55	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	105-110
32707739-8	2020	In conclusion, our findings suggest that these N-glycans have distinct roles in the ER-exit of GluA1 and GluA2 homo-oligomers; N-glycan at GluA1N63 is a prerequisite for GluA1 ER-exit, whereas N-glycans at GluA1N363 and GluA2N370 control the ER-exit rate.	n-glycan	47-55	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	139-144
32754154-4	2020	Here we extend the biophysical and biological characterization of IL-33trap variants, and show that IL-33trap is a stable protein with a monomeric profile both at physiological temperatures and during liquid storage at 4 C. Reducing the N-glycan heterogeneity and complexity of IL-33trap via GlycoDelete engineering neither affects its stability nor its inhibitory activity against IL-33.	n-glycan	237-245	interleukin 33	Homo sapiens	100-105
32754154-4	2020	Here we extend the biophysical and biological characterization of IL-33trap variants, and show that IL-33trap is a stable protein with a monomeric profile both at physiological temperatures and during liquid storage at 4 C. Reducing the N-glycan heterogeneity and complexity of IL-33trap via GlycoDelete engineering neither affects its stability nor its inhibitory activity against IL-33.	n-glycan	237-245	interleukin 33	Homo sapiens	100-105
32754154-4	2020	Here we extend the biophysical and biological characterization of IL-33trap variants, and show that IL-33trap is a stable protein with a monomeric profile both at physiological temperatures and during liquid storage at 4 C. Reducing the N-glycan heterogeneity and complexity of IL-33trap via GlycoDelete engineering neither affects its stability nor its inhibitory activity against IL-33.	n-glycan	237-245	interleukin 33	Homo sapiens	100-105
32620165-5	2020	Interestingly, structural hindrance by N-glycan on PD-L1 in fixed samples impedes its recognition by PD-L1 diagnostic antibodies.	n-glycan	39-47	CD274 molecule	Homo sapiens	51-56
32620165-5	2020	Interestingly, structural hindrance by N-glycan on PD-L1 in fixed samples impedes its recognition by PD-L1 diagnostic antibodies.	n-glycan	39-47	CD274 molecule	Homo sapiens	101-106
32203567-10	2020	We propose that beta-catenin/CBP signaling promotes EGFR oncogenic activity in OSCC by inhibiting its N-glycan antennary fucosylation through transcriptional repression of FUT2 and FUT3.	n-glycan	102-110	catenin beta 1	Homo sapiens	16-28
32298759-8	2020	Together these results indicate that proper N-glycan processing plays an important role in directing GLUT1 to the cell surface and that disruption of mannosidase activity results in aberrant degradation of GLUT1 by the ERAD pathway.	n-glycan	44-52	solute carrier family 2 member 1	Homo sapiens	101-106
31269834-2	2020	The effect of beta-galactosidase on the N-glycan changes in serum from mice intravenously treated with beta-galactosidase was observed by linear ion-trap quadrupole-electrospray ionization mass spectrometry (LTQ-ESI-MS).	n-glycan	40-48	galactosidase, beta 1	Mus musculus	14-32
31269834-2	2020	The effect of beta-galactosidase on the N-glycan changes in serum from mice intravenously treated with beta-galactosidase was observed by linear ion-trap quadrupole-electrospray ionization mass spectrometry (LTQ-ESI-MS).	n-glycan	40-48	galactosidase, beta 1	Mus musculus	103-121
31822129-6	2020	The procedure was also successfully tried on hydrophilic tetra- and hexa-peptides of Ribonuclease B carrying an N-glycosylation site occupied with "high-mannose" N-glycan chains.	n-glycan	162-170	hexosaminidase subunit alpha	Homo sapiens	68-72
32376684-7	2020	Loss of an individual N-glycan on EOGT did not affect its endoplasmic reticulum (ER) localization, enzyme activity, and ability to O-GlcNAcylate Notch1 in HEK293T cells.	n-glycan	22-30	EGF domain specific O-linked N-acetylglucosamine transferase	Homo sapiens	34-38
32612952-3	2020	Among the specific N-glycan structures, bisecting N-Acetylglucosamine (GlcNAc) is a beta1,4-linked GlcNAc attached to the core beta-mannose residue, and is catalyzed by glycosyltransferase MGAT3.	n-glycan	19-27	BCL2 related protein A1	Homo sapiens	84-89
32612952-3	2020	Among the specific N-glycan structures, bisecting N-Acetylglucosamine (GlcNAc) is a beta1,4-linked GlcNAc attached to the core beta-mannose residue, and is catalyzed by glycosyltransferase MGAT3.	n-glycan	19-27	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	189-194
32350116-1	2020	Core fucose is an N-glycan structure synthesized by alpha1,6-fucosyltransferase 8 (FUT8) localized to the Golgi apparatus and critically regulates the functions of various glycoproteins.	n-glycan	18-26	fucosyltransferase 8	Homo sapiens	83-87
32203567-10	2020	We propose that beta-catenin/CBP signaling promotes EGFR oncogenic activity in OSCC by inhibiting its N-glycan antennary fucosylation through transcriptional repression of FUT2 and FUT3.	n-glycan	102-110	CREB binding protein	Homo sapiens	29-32
32203567-10	2020	We propose that beta-catenin/CBP signaling promotes EGFR oncogenic activity in OSCC by inhibiting its N-glycan antennary fucosylation through transcriptional repression of FUT2 and FUT3.	n-glycan	102-110	epidermal growth factor receptor	Homo sapiens	52-56
32469948-7	2020	In addition, we knocked in the MdsI (alpha-1,2-mannosidase) gene to reduce mannosylation and the GnTI (beta-1,2-N-acetylglucosaminyltransferase I) and GnTII genes to produce human N-glycan structures.	n-glycan	180-188	mannosidase alpha class 1A member 2	Homo sapiens	37-58
32469948-7	2020	In addition, we knocked in the MdsI (alpha-1,2-mannosidase) gene to reduce mannosylation and the GnTI (beta-1,2-N-acetylglucosaminyltransferase I) and GnTII genes to produce human N-glycan structures.	n-glycan	180-188	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	97-101
32355592-7	2020	Enzyme activity of the N-glycan processing enzymes involved in cell wall softening, alpha-mannosidase and beta-d-N-acetylhexosaminidase revealed a significant reduction in their activity by 2 and 3.5-fold, respectively.	n-glycan	23-31	alpha-mannosidase	Solanum lycopersicum	84-101
32298669-5	2020	MALDI-MS was used for N-glycan analysis of IgA1 samples.	n-glycan	22-30	immunoglobulin heavy constant alpha 1	Homo sapiens	43-47
32029268-0	2020	Microwave irradiation-assisted high-efficiency N-glycan release using oriented immobilization of PNGase F on magnetic particles.	n-glycan	47-55	N-glycanase 1	Homo sapiens	97-103
32220931-3	2020	The acceptor substrate preferences of FUT8 are well characterized and provide a framework for understanding N-glycan maturation in the Golgi; however the structural basis for these substrate preferences and the mechanism through which catalysis is achieved remain unknown.	n-glycan	108-116	fucosyltransferase 8	Homo sapiens	38-42
31932825-2	2020	The Env immunogen is a heavily glycosylated protein composed of 3 identical surface gp120 and gp41 subunits that form into a trimer of heterodimers (3 x 28 N-glycan sites).	n-glycan	156-164	endogenous retrovirus group K member 20	Homo sapiens	4-7
32212632-0	2020	Site-specific and Quantitative N-glycan Heterogeneity Analysis of the Charge Isomers of an Anti-VEGF Recombinant Fusion Protein by High-resolution 2-dimensional Gel Electrophoresis and Mass Spectrometry.	n-glycan	31-39	vascular endothelial growth factor A	Homo sapiens	96-100
32212632-6	2020	Then, combined with the quantitative analysis strategy of site-specific N-glycan heterogeneity based on the diagnostic MS2 ion (peptides+GlcNAc, Y1 ions) of glycopeptides, an integrated approach for the quantitation of site-specific N-glycan heterogeneities among charge isomers was established.	n-glycan	72-80	MS2	Homo sapiens	119-122
31057084-0	2020	Role of N-glycan in the structural changes of myelin oligodendrocyte glycoprotein and its complex with an antibody.	n-glycan	8-16	myelin oligodendrocyte glycoprotein	Homo sapiens	46-81
32035902-5	2020	Surprisingly, the structures are nearly identical to a structure of hormone-bound, N-glycan-free ECD, which suggested that the GlcNAc might affect CTR dynamics not observed in the static crystallographic snapshots.	n-glycan	83-91	calcitonin receptor	Homo sapiens	147-150
32182948-6	2020	We observed associations between two genetic variants (rs505922 and rs687621), AITD status, the secretion of Desmoglein-2 protein, and the profile of two IgG N-glycan traits in AITD, but further studies need to be performed to better understand their crosstalk in AITD.	n-glycan	158-166	desmoglein 2	Homo sapiens	109-121
32222585-3	2020	Pioneer studies on FcgammaR N-glycans have unveiled an additional complexity in that the N-glycan linked on the Asn-162 of FcgammaRIIIa was shown to be directly involved in the strong affinity for afucosylated IgG1.	n-glycan	28-36	Fc gamma receptor IIIa	Homo sapiens	123-135
31860772-9	2020	The transcript levels of the FUT3 and FUT6 genes responsible for the enzymes that add fucose to N-glycan antennae were significantly decreased in all ccRCC tissues relative to matching nontumor tissues.	n-glycan	96-104	fucosyltransferase 3 (Lewis blood group)	Homo sapiens	29-33
31860772-9	2020	The transcript levels of the FUT3 and FUT6 genes responsible for the enzymes that add fucose to N-glycan antennae were significantly decreased in all ccRCC tissues relative to matching nontumor tissues.	n-glycan	96-104	fucosyltransferase 6	Homo sapiens	38-42
31908039-4	2020	In this study, we showed that the N-glycan structures on wild type (WT), internal tandem duplication (ITD), and tyrosine kinase domain (TKD) mutants of FLT3 were different.	n-glycan	34-42	fms related receptor tyrosine kinase 3	Homo sapiens	152-156
32080177-4	2020	Here, we report the crystal structure of FUT8 complexed with GDP and a biantennary complex N-glycan (G0), which provides insight into both substrate recognition and catalysis.	n-glycan	91-99	fucosyltransferase 8	Homo sapiens	41-45
32296760-6	2020	In particular, investigating the activation of the catecholamine beta2-adrenergic receptor by a pathogen revealed that traction forces directly exerted on the N-terminus of the receptor via N-glycan chains activate specific signaling pathways.	n-glycan	190-198	adrenoceptor beta 2	Homo sapiens	65-90
32296760-7	2020	These findings open new perspectives in GPCR biology and pharmacology since most GPCRs express N-glycan chains in their N-terminus, which might similarly be involved in the interaction with cell-surface glycan-specific lectins in the context of cell-to-cell mechanical signaling.	n-glycan	95-103	vomeronasal 1 receptor 17 pseudogene	Homo sapiens	40-44
31216452-4	2020	Evidences cleared that EPO"s activity increased by numbers of N-glycan moieties with presence of sialic acids at their terminus.	n-glycan	62-70	erythropoietin	Homo sapiens	23-26
31462733-3	2020	Here, mutant CALR accumulated in the Golgi apparatus, and its entrance into the secretion pathway and capacity to interact with N-glycan were required for its oncogenic capacity via the constitutive activation of MPL.	n-glycan	128-136	calreticulin	Homo sapiens	13-17
31462733-3	2020	Here, mutant CALR accumulated in the Golgi apparatus, and its entrance into the secretion pathway and capacity to interact with N-glycan were required for its oncogenic capacity via the constitutive activation of MPL.	n-glycan	128-136	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	213-216
31732167-5	2019	To preferentially expose the CD4bs to B cells, we eliminated proximal N-glycans while maintaining the native-like state of the cleavage-independent NFL trimers, followed by gradual N-glycan restoration coupled with heterologous boosting.	n-glycan	70-78	T-cell surface glycoprotein CD4	Oryctolagus cuniculus	29-32
32306330-3	2020	Although Fbs proteins recognize innermost Man3GlcNAc2 structure that is commonly found in most N-glycan structures, they preferentially bind high-mannose-type glycans.	n-glycan	95-103	F-box protein 8	Homo sapiens	9-12
32812835-5	2020	The impact of different types and varying levels of enriched afucosylated N-glycan species on the in vitro bioactivities is assessed for an antibody whose target is aggregated amyloid beta (Abeta).	n-glycan	74-82	amyloid beta precursor protein	Homo sapiens	190-195
32403105-1	2020	OBJECTIVE: Golgi alpha-mannosidase II (GM II) is one of the crucial enzymes in the process of N-glycan processing.	n-glycan	94-102	mannosidase alpha class 2A member 1	Homo sapiens	11-37
31550741-4	2020	RESULTS: Two proteins, kinesin-like protein (KI13B) and proliferating cell nuclear antigen (PCNA), have been identified that carry N-glycan epitopes after conjugation with aptamer sequences.	n-glycan	131-139	proliferating cell nuclear antigen	Homo sapiens	56-90
31550741-4	2020	RESULTS: Two proteins, kinesin-like protein (KI13B) and proliferating cell nuclear antigen (PCNA), have been identified that carry N-glycan epitopes after conjugation with aptamer sequences.	n-glycan	131-139	proliferating cell nuclear antigen	Homo sapiens	92-96
31681747-14	2019	In the co-expression analysis, overlapped co-expression signal pathways for RHOT2 and TCIRG1 were sphingolipid metabolism and N-glycan biosynthesis.	n-glycan	126-134	ras homolog family member T2	Homo sapiens	76-81
31395617-5	2019	RESULTS: Two patients in the clinically defined cohort had rare loss-of-function variants in ALG9, which encodes a protein required for addition of specific mannose molecules to the assembling N-glycan precursors in the endoplasmic reticulum lumen.	n-glycan	193-201	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	93-97
31364262-7	2019	Potential N-glycan diagnostic markers that emerge include the oligomannose structure, (Hex)6 + (Man)3 (GlcNAc)2 , and the complex neutral structure, (Hex)2 (HexNAc)2 (Deoxyhexose)1 + (Man)3 (GlcNAc)2 .	n-glycan	10-18	hematopoietically expressed homeobox	Homo sapiens	87-90
31364262-7	2019	Potential N-glycan diagnostic markers that emerge include the oligomannose structure, (Hex)6 + (Man)3 (GlcNAc)2 , and the complex neutral structure, (Hex)2 (HexNAc)2 (Deoxyhexose)1 + (Man)3 (GlcNAc)2 .	n-glycan	10-18	hematopoietically expressed homeobox	Homo sapiens	150-153
31681747-14	2019	In the co-expression analysis, overlapped co-expression signal pathways for RHOT2 and TCIRG1 were sphingolipid metabolism and N-glycan biosynthesis.	n-glycan	126-134	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3	Homo sapiens	86-92
31681747-15	2019	Conclusions: Based on the results of comprehensive bioinformatic analysis, we proposed that aberrant DDX39B regulated RHOT2-32938-RI and TCIRG1-17288-RI might be associated with the tumorigenesis, metastasis, and poor prognosis of KIRC via sphingolipid metabolism or N-glycan biosynthesis pathway.	n-glycan	267-275	DExD-box helicase 39B	Homo sapiens	101-107
31681747-15	2019	Conclusions: Based on the results of comprehensive bioinformatic analysis, we proposed that aberrant DDX39B regulated RHOT2-32938-RI and TCIRG1-17288-RI might be associated with the tumorigenesis, metastasis, and poor prognosis of KIRC via sphingolipid metabolism or N-glycan biosynthesis pathway.	n-glycan	267-275	ras homolog family member T2	Homo sapiens	118-123
31681747-15	2019	Conclusions: Based on the results of comprehensive bioinformatic analysis, we proposed that aberrant DDX39B regulated RHOT2-32938-RI and TCIRG1-17288-RI might be associated with the tumorigenesis, metastasis, and poor prognosis of KIRC via sphingolipid metabolism or N-glycan biosynthesis pathway.	n-glycan	267-275	T cell immune regulator 1, ATPase H+ transporting V0 subunit a3	Homo sapiens	137-143
31597281-2	2019	An established method for the linkage isomer-specific characterization of N-glycan sialylation is based on the linkage-specific derivatization of sialylated glycoconjugates, inducing ethyl esterification of alpha2,6-linked sialic acids and lactonization of alpha2,3-linked sialic acids.	n-glycan	74-82	immunoglobulin kappa variable 2-24	Homo sapiens	257-265
31375533-4	2019	Expression of these epitopes in N-glycan was elevated in mice lacking the biosynthetic enzyme of bisecting GlcNAc, GnT-III, and was conversely suppressed by GnT-III overexpression in cells.	n-glycan	32-40	mannoside acetylglucosaminyltransferase 3	Mus musculus	115-122
31375533-4	2019	Expression of these epitopes in N-glycan was elevated in mice lacking the biosynthetic enzyme of bisecting GlcNAc, GnT-III, and was conversely suppressed by GnT-III overexpression in cells.	n-glycan	32-40	mannoside acetylglucosaminyltransferase 3	Mus musculus	157-164
31395657-7	2019	Our results provide detailed mechanistic insights into the regulation of glycosyltransferase interactions, the transitions between B4GALT1 and ST6GAL1 homo- and heteromers in the Golgi, and cooperative B4GALT1/ST6GAL1 function in N-glycan synthesis.	n-glycan	230-238	beta-1,4-galactosyltransferase 1	Homo sapiens	131-138
31395657-7	2019	Our results provide detailed mechanistic insights into the regulation of glycosyltransferase interactions, the transitions between B4GALT1 and ST6GAL1 homo- and heteromers in the Golgi, and cooperative B4GALT1/ST6GAL1 function in N-glycan synthesis.	n-glycan	230-238	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	143-150
31395657-7	2019	Our results provide detailed mechanistic insights into the regulation of glycosyltransferase interactions, the transitions between B4GALT1 and ST6GAL1 homo- and heteromers in the Golgi, and cooperative B4GALT1/ST6GAL1 function in N-glycan synthesis.	n-glycan	230-238	beta-1,4-galactosyltransferase 1	Homo sapiens	202-209
31395657-7	2019	Our results provide detailed mechanistic insights into the regulation of glycosyltransferase interactions, the transitions between B4GALT1 and ST6GAL1 homo- and heteromers in the Golgi, and cooperative B4GALT1/ST6GAL1 function in N-glycan synthesis.	n-glycan	230-238	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	210-217
31667130-4	2019	It has long been known that N-glycan biosynthesis can be inhibited by disruption of the first committed enzyme, dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 (DPAGT1).	n-glycan	28-36	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Rattus norvegicus	112-170
31667130-4	2019	It has long been known that N-glycan biosynthesis can be inhibited by disruption of the first committed enzyme, dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 (DPAGT1).	n-glycan	28-36	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1	Rattus norvegicus	172-178
31507595-8	2019	When glycoforms of CD52-Fc were fractionated by anion exchange MonoQ-GL chromatography, bioactive fractions displayed mainly tetra-antennary, alpha-2,3 sialylated N-glycan structures and a lower relative abundance of bisecting GlcNAc structures compared to non-bioactive fractions.	n-glycan	163-171	CD52 molecule	Homo sapiens	19-23
31062865-5	2019	Using intact glycopeptide characterization, the EPO-Fc was observed to maintain their individual EPO and Fc N-glycan characteristics in which the EPO region presented bi-, tri-, and tetra-branched N-glycan structures, while the Fc N-glycan displayed mostly biantennary glycans.	n-glycan	108-116	erythropoietin	Cricetulus griseus	48-51
31062865-5	2019	Using intact glycopeptide characterization, the EPO-Fc was observed to maintain their individual EPO and Fc N-glycan characteristics in which the EPO region presented bi-, tri-, and tetra-branched N-glycan structures, while the Fc N-glycan displayed mostly biantennary glycans.	n-glycan	197-205	erythropoietin	Cricetulus griseus	48-51
31062865-5	2019	Using intact glycopeptide characterization, the EPO-Fc was observed to maintain their individual EPO and Fc N-glycan characteristics in which the EPO region presented bi-, tri-, and tetra-branched N-glycan structures, while the Fc N-glycan displayed mostly biantennary glycans.	n-glycan	197-205	erythropoietin	Cricetulus griseus	48-51
31468229-4	2019	N-Glycoprofiling analysis of G-hPRL provided: (i) identification of each N-glycan structure and relative intensity; (ii) average N-glycan mass; (iii) molecular mass of the whole glycoprotein and relative carbohydrate mass fraction; (iv) mass fraction of each monosaccharide.	n-glycan	73-81	prolactin	Homo sapiens	31-35
31468229-4	2019	N-Glycoprofiling analysis of G-hPRL provided: (i) identification of each N-glycan structure and relative intensity; (ii) average N-glycan mass; (iii) molecular mass of the whole glycoprotein and relative carbohydrate mass fraction; (iv) mass fraction of each monosaccharide.	n-glycan	129-137	prolactin	Homo sapiens	31-35
31468229-8	2019	The "in vitro" bioactivity of HEK-G-hPRL was ~ fourfold lower than that of native G-hPRL, with which it had in common also the number of N-glycan structures.	n-glycan	137-145	prolactin	Homo sapiens	36-40
31362986-2	2019	Little is known about the impact of N-glycan modifications of IgA1 and IgA2 on binding to the Fcalpha receptor (FcalphaRI), which is also heavily glycosylated at its extracellular domain.	n-glycan	36-44	immunoglobulin heavy constant alpha 1	Homo sapiens	62-66
31362986-2	2019	Little is known about the impact of N-glycan modifications of IgA1 and IgA2 on binding to the Fcalpha receptor (FcalphaRI), which is also heavily glycosylated at its extracellular domain.	n-glycan	36-44	Fc alpha receptor	Homo sapiens	94-122
31362986-3	2019	Here, we transiently expressed human epidermal growth factor receptor 2 (HER2)-binding monomeric IgA1, IgA2m(1), and IgA2m(2) variants in Nicotiana benthamiana DeltaXT/FT plants lacking the enzymes responsible for generating nonhuman N-glycan structures.	n-glycan	234-242	erb-b2 receptor tyrosine kinase 2	Homo sapiens	37-71
31362986-3	2019	Here, we transiently expressed human epidermal growth factor receptor 2 (HER2)-binding monomeric IgA1, IgA2m(1), and IgA2m(2) variants in Nicotiana benthamiana DeltaXT/FT plants lacking the enzymes responsible for generating nonhuman N-glycan structures.	n-glycan	234-242	erb-b2 receptor tyrosine kinase 2	Homo sapiens	73-77
31056268-4	2019	It has been validated with wild-type N-glycans from human transferrin and RNase B and then was successfully applied to investigate N-glycan profiles of the transferrin in human serum and a monoclonal antibody (mAb).	n-glycan	37-45	transferrin	Homo sapiens	156-167
31307013-5	2019	RESULTS: We demonstrate that an N-glycan at N347 within the CBG RCL limits the 9G12 antibody from recognising its epitope, whereas the 12G2 antibody reactivity is unaffected, thereby contributing to discrepancies in ELISA measurements using these two antibodies.	n-glycan	32-40	serpin family A member 6	Homo sapiens	60-63
31420549-1	2019	The Arabidopsis ER-alpha-mannosidase I (MNS3) generates an oligomannosidic N-glycan structure that is characteristically found on ER-resident glycoproteins.	n-glycan	75-83	alpha-mannosidase 3	Arabidopsis thaliana	40-44
31443222-5	2019	The two N-glycan molecules, which constitute a significant part of the irisin glycoprotein, regulate the browning of adipocytes, which is the most important function of irisin.	n-glycan	8-16	fibronectin type III domain containing 5	Homo sapiens	71-77
31443222-5	2019	The two N-glycan molecules, which constitute a significant part of the irisin glycoprotein, regulate the browning of adipocytes, which is the most important function of irisin.	n-glycan	8-16	fibronectin type III domain containing 5	Homo sapiens	169-175
31185295-0	2019	N-Glycan-calnexin interactions in human factor VII secretion and deficiency.	n-glycan	0-8	calnexin	Homo sapiens	9-17
31092533-2	2019	GAS secretes EndoS, an endoglycosidase that specifically cleaves the conserved N-glycan on IgG antibodies.	n-glycan	79-87	gastrin	Homo sapiens	0-3
31311714-8	2019	PNG catalyzes the cleavage of the proximal N-acetylglucosamine residue of an N-glycan from the asparagine residue of a protein, a step in the degradation of misfolded glycoproteins.	n-glycan	77-85	N-glycanase 1	Homo sapiens	0-3
31215021-7	2019	Furthermore, studies of N-glycan alterations have successfully been used to identify individuals with rare types of diabetes (such as the HNF1A-MODY), and also to evaluate functional significance of novel diabetes-associated mutations.	n-glycan	24-32	HNF1 homeobox A	Homo sapiens	138-143
31136099-6	2019	Postproteomic site-specific N-glycan analyses showed that human complement C3 bears high-mannose and hybrid glycoforms rather than complex glycoforms at Asn85.	n-glycan	28-36	complement C3	Homo sapiens	64-77
30933786-2	2019	The Manbeta(1   4)GlcNAc disaccharide may be used as a key intermediate for elaboration into more complex N-glycan structures providing a route to N-glycan oxazolines as donor substrates for ENGase enzymes that is considerably shorter than those reported previously.	n-glycan	106-114	endo-beta-N-acetylglucosaminidase	Homo sapiens	191-197
31126879-5	2019	Asymmetric binding of SF12 was associated with distinct N-glycan conformations across Env protomers, demonstrating intra-Env glycan heterogeneity.	n-glycan	56-64	endogenous retrovirus group K member 20	Homo sapiens	121-124
31079452-4	2019	Using the AXL receptor tyrosine kinase (AXL) as a model glycoprotein with multiple N-glycosylation sites, we show that those LCMS features that could be grouped into graph networks on the basis of glycan mass and retention time differences were actually N-glycopeptides with the same peptide backbone but different N-glycan compositions.	n-glycan	315-323	AXL receptor tyrosine kinase	Homo sapiens	10-13
31079452-4	2019	Using the AXL receptor tyrosine kinase (AXL) as a model glycoprotein with multiple N-glycosylation sites, we show that those LCMS features that could be grouped into graph networks on the basis of glycan mass and retention time differences were actually N-glycopeptides with the same peptide backbone but different N-glycan compositions.	n-glycan	315-323	AXL receptor tyrosine kinase	Homo sapiens	40-43
30868896-14	2019	Gene expression and N-glycan trimming in the ER and Calnexin/Calreticulin cycle were two significant enriched pathways.	n-glycan	20-28	calnexin	Homo sapiens	52-60
30868896-14	2019	Gene expression and N-glycan trimming in the ER and Calnexin/Calreticulin cycle were two significant enriched pathways.	n-glycan	20-28	calreticulin	Homo sapiens	61-73
31055873-6	2019	Consequently, VWF monomers contain complex N-glycan and O-glycan structures that, together, account for approximately 20% of the final monomeric mass.	n-glycan	43-51	von Willebrand factor	Homo sapiens	14-17
30971450-4	2019	Here, we investigated the contribution of individual amino acid residues within the TMD of Arabidopsis (Arabidopsis thaliana) and Nicotiana tabacum GnTI toward Golgi localization and n-glycan processing.	n-glycan	183-191	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like	Nicotiana tabacum	148-152
30971450-6	2019	Subsequent subcellular localization of fluorescent fusion proteins and n-glycan profiling revealed that a conserved Gln residue in the GnTI TMD is essential for its cis/medial-Golgi localization.	n-glycan	71-79	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	135-139
30776362-3	2019	While some CDG-II subtypes are associated with specific N-glycan structures, others only produce changes in relative levels, reinforcing the demand for quantification methods.	n-glycan	56-64	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	11-17
30641224-9	2019	Relative abundances of several N-glycan structures were dramatically altered by the neuraminidase treatment, which selectively removed sialic acid residues.	n-glycan	31-39	neuraminidase 1	Homo sapiens	84-97
30614075-2	2019	Copper transporter 1 (CTR1), which contains one N-glycan on Asn15 , mediates cellular transport of cisplatin (cDDP), and plays an important role in the process of cDDP-resistance in EOC.	n-glycan	48-56	solute carrier family 31 member 1	Homo sapiens	0-20
30614075-2	2019	Copper transporter 1 (CTR1), which contains one N-glycan on Asn15 , mediates cellular transport of cisplatin (cDDP), and plays an important role in the process of cDDP-resistance in EOC.	n-glycan	48-56	solute carrier family 31 member 1	Homo sapiens	22-26
30737276-0	2019	The N-glycan structures of the antigenic variants of chlorovirus PBCV-1 major capsid protein help to identify the virus-encoded glycosyltransferases.	n-glycan	4-12	Major capsid protein	Paramecium bursaria Chlorella virus 1	72-92
31019513-11	2019	Consistent with these findings of altered CD22 organization, we found that mutation of N-glycan sites attenuated CD22 phosphorylation upon BCR stimulation, and consequently, increased BCR signaling.	n-glycan	87-95	CD22 molecule	Homo sapiens	42-46
31019513-11	2019	Consistent with these findings of altered CD22 organization, we found that mutation of N-glycan sites attenuated CD22 phosphorylation upon BCR stimulation, and consequently, increased BCR signaling.	n-glycan	87-95	CD22 molecule	Homo sapiens	113-117
30641082-0	2019	N-glycan Utilization by Bifidobacterium Gut Symbionts Involves a Specialist beta-Mannosidase.	n-glycan	0-8	mannosidase beta	Homo sapiens	76-92
30221828-3	2019	The beneficial impact of 1,3,4-O-Bu3 ManNAc on EPO glycan quality, while evident in wild-type CHO cells, is particularly pronounced in glycoengineered CHO cells with stable overexpression of beta-1,4- and beta-1,6-N-acetylglucosaminyltransferases (GnTIV and GnTV) and alpha-2,6-sialyltransferase (ST6) enzymes responsible for N-glycan antennarity and sialylation.	n-glycan	326-334	erythropoietin	Cricetulus griseus	47-50
30221828-7	2019	Moreover, a detailed mass spectrometric ESI-LC-MS/MS characterization of glycans at each of the three N-glycosylation sites of EPO showed that the 1st N-site is highly sialylated and either the negative impact of NaBu or the beneficial effect 1,3,4-O-Bu3 ManNAc treatments mainly affects the 2nd and 3rd N-glycan sites of EPO protein.	n-glycan	304-312	erythropoietin	Cricetulus griseus	127-130
30873590-0	2019	Complex N-glycan promotes CD133 mono-ubiquitination and secretion.	n-glycan	8-16	prominin 1	Homo sapiens	26-31
30873590-4	2019	In this study, we report that secreted CD133 has a complex-type N-glycosylation and is modified by beta1,6GlcNAc N-glycan.	n-glycan	113-121	prominin 1	Homo sapiens	39-44
30513349-2	2019	Due to differences in N-glycan moieties, two members of the serpin superfamily, alpha-1-antitrypsin (A1AT) and plasma protease C1 inhibitor (C1INH), are currently derived from human plasma for treating A1AT and C1INH deficiency.	n-glycan	22-30	serpin family A member 1	Homo sapiens	80-99
30365935-7	2019	Nine N-glycan peaks (GPs (GP1, GP4, GP7, GP11, GP17, GP19, GP22, GP26, GP29)) were found to predict case status based on Akaike"s information criterion (AIC) and Bayesian information criterion (BIC) model selection.	n-glycan	5-13	GTP binding protein 1	Homo sapiens	26-29
30448401-2	2019	Here we investigate a new role for tumor necrosis factor alpha in promoting N-glycan-processing deficiency at the surface of the eye through inhibition of N-acetylglucosaminyltransferase expression in the Golgi.	n-glycan	76-84	tumor necrosis factor	Homo sapiens	35-62
30543411-3	2019	Here, we characterize the interactions between the fimbrial adhesin FimH from uropathogenic Escherichia coli strains and its natural high-mannose type N-glycan binding epitopes on uroepithelial glycoproteins.	n-glycan	151-159	adhesin	Escherichia coli	60-67
30483742-7	2019	Furthermore, we found that deglycosylated PTX3 (dePTX3) by tunicamycin (TM), which is N-glycan precursor biosynthesis blocker, and PNGase F significantly reduced the survival and migration of lung cancer cells.	n-glycan	86-94	pentraxin 3	Homo sapiens	42-46
30466347-5	2019	In this study, chemoenzymatic glycoengineering incorporating an endo-beta-N-acetylglucosaminidase (ENGase) EndoS2 and its mutant with transglycosylation activity was used to generate mAb glycoforms with highly homogeneous and well-defined N-glycans to better understand and precisely evaluate the effect of each N-glycan structure on Fc effector functions and protein stability.	n-glycan	239-247	O-GlcNAcase	Homo sapiens	69-97
30466347-5	2019	In this study, chemoenzymatic glycoengineering incorporating an endo-beta-N-acetylglucosaminidase (ENGase) EndoS2 and its mutant with transglycosylation activity was used to generate mAb glycoforms with highly homogeneous and well-defined N-glycans to better understand and precisely evaluate the effect of each N-glycan structure on Fc effector functions and protein stability.	n-glycan	239-247	endo-beta-N-acetylglucosaminidase	Homo sapiens	99-105
30058762-4	2019	Indeed, on each of the 6 N-glycosylation sites of the IDUA, a single N-glycan composed of a core Man3 GlcNAc2 carrying one beta(1,2)-xylose and one alpha(1,3)-fucose epitope (M3XFGN2) was identified, highlighting the high homogeneity of the production system.	n-glycan	69-77	alpha-L-iduronidase	Homo sapiens	54-58
30058762-4	2019	Indeed, on each of the 6 N-glycosylation sites of the IDUA, a single N-glycan composed of a core Man3 GlcNAc2 carrying one beta(1,2)-xylose and one alpha(1,3)-fucose epitope (M3XFGN2) was identified, highlighting the high homogeneity of the production system.	n-glycan	69-77	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	123-131
30365935-7	2019	Nine N-glycan peaks (GPs (GP1, GP4, GP7, GP11, GP17, GP19, GP22, GP26, GP29)) were found to predict case status based on Akaike"s information criterion (AIC) and Bayesian information criterion (BIC) model selection.	n-glycan	5-13	CD36 molecule	Homo sapiens	31-34
30365935-7	2019	Nine N-glycan peaks (GPs (GP1, GP4, GP7, GP11, GP17, GP19, GP22, GP26, GP29)) were found to predict case status based on Akaike"s information criterion (AIC) and Bayesian information criterion (BIC) model selection.	n-glycan	5-13	S100 calcium binding protein A10	Homo sapiens	41-45
30584598-1	2018	Objective: To identify whether somatic mutations in SLC35A2 alter N-glycan structures in human brain tissues and cause nonlesional focal epilepsy (NLFE) or mild malformation of cortical development (mMCD).	n-glycan	66-74	solute carrier family 35 member A2	Homo sapiens	52-59
30455330-12	2019	N-glycan profile and hs-CRP could both be used as tools, alone or as adjuncts to existing pathways, for identifying individuals at high risk of carrying a damaging HNF1A allele.	n-glycan	0-8	HNF1 homeobox A	Homo sapiens	164-169
30305355-8	2019	These microdomains have a limited number of N-glycan-sequon combinations that may allow the anticipation of immune escape variants.IMPORTANCE The Env protein of HIV is highly glycosylated, and the sites of glycosylation can change as the virus mutates during immune evasion.	n-glycan	44-52	endogenous retrovirus group K member 20	Homo sapiens	146-149
30592377-0	2019	Increases in Tumor N-Glycan Polylactosamines Associated with Advanced HER2-Positive and Triple-Negative Breast Cancer Tissues.	n-glycan	19-27	erb-b2 receptor tyrosine kinase 2	Homo sapiens	70-74
30584598-5	2018	Glycome analysis revealed the presence of an aberrant N-glycan series, including high degrees of N-acetylglucosamine, in brain tissues with SLC35A2 mutations.	n-glycan	54-62	solute carrier family 35 member A2	Homo sapiens	140-147
29947113-5	2018	In MAN1B1-CDG, the abnormal accumulating N-glycan structures are mostly absent or found in trace amounts in total human serum.	n-glycan	41-49	mannosidase alpha class 1B member 1	Homo sapiens	3-9
30297340-3	2018	We found that ~55% of these splicing changes depend on ELL2, a transcription elongation factor that influences expression levels and splicing patterns of ASC signature genes, genes in the cell-cycle and N-glycan biosynthesis and processing pathways, and the secretory versus membrane forms of the IgH mRNA.	n-glycan	203-211	elongation factor for RNA polymerase II 2	Mus musculus	55-59
30296068-1	2018	The N-glycan pattern of lactoperoxidase (LPO) from buffalo and goat milk was analyzed with the corresponding site of attachment.	n-glycan	4-12	lactoperoxidase	Capra hircus	24-39
30296068-1	2018	The N-glycan pattern of lactoperoxidase (LPO) from buffalo and goat milk was analyzed with the corresponding site of attachment.	n-glycan	4-12	lactoperoxidase	Capra hircus	41-44
30274773-7	2018	Both protease inhibitor Furin and N-glycan biosynthesis inhibitor swainsonine could decrease cell mobility in GnT-V-U87 transfectants and other glioma cell lines.	n-glycan	34-42	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	110-115
30290597-4	2018	These 12 markers were mainly involved in the metabolic pathways of insulin resistance, glycolysis/gluconeogenesis, tricarboxylic acid cycle, nonabsorbable carbohydrate metabolism, and N-glycan biosynthesis.	n-glycan	184-192	insulin	Homo sapiens	67-74
30305426-0	2018	XBP1s activation can globally remodel N-glycan structure distribution patterns.	n-glycan	38-46	X-box binding protein 1	Homo sapiens	0-4
30305426-4	2018	Here, we show that a key functional output of XBP1s activation is a cell type-dependent shift in the distribution of N-glycan structures on endogenous membrane and secreted proteomes.	n-glycan	117-125	X-box binding protein 1	Homo sapiens	46-50
30305426-7	2018	mRNA profiling experiments suggest that XBP1s-mediated remodeling of the N-glycome is, at least in part, a consequence of coordinated transcriptional resculpting of N-glycan maturation pathways by XBP1s.	n-glycan	165-173	X-box binding protein 1	Homo sapiens	40-44
30305426-8	2018	The discovery of XBP1s-induced N-glycan structural remodeling on a glycome-wide scale suggests that XBP1s can act as a master regulator of N-glycan maturation.	n-glycan	31-39	X-box binding protein 1	Homo sapiens	17-21
30305426-8	2018	The discovery of XBP1s-induced N-glycan structural remodeling on a glycome-wide scale suggests that XBP1s can act as a master regulator of N-glycan maturation.	n-glycan	31-39	X-box binding protein 1	Homo sapiens	100-104
30305426-8	2018	The discovery of XBP1s-induced N-glycan structural remodeling on a glycome-wide scale suggests that XBP1s can act as a master regulator of N-glycan maturation.	n-glycan	139-147	X-box binding protein 1	Homo sapiens	17-21
30305426-8	2018	The discovery of XBP1s-induced N-glycan structural remodeling on a glycome-wide scale suggests that XBP1s can act as a master regulator of N-glycan maturation.	n-glycan	139-147	X-box binding protein 1	Homo sapiens	100-104
30356796-8	2018	IgG1 and IgG3 were detected against a range of N-glycan core structures, but IgG2 and IgG4, when present, were specific for the core alpha3-fucose and xylose motifs that were previously found to be IgE targets in schistosomiasis, and in allergies.	n-glycan	47-55	immunoglobulin heavy constant gamma 3 (G3m marker)	Homo sapiens	9-13
29778566-7	2018	Notably, the CIgG-integrin-FAK signaling depends on the N-glycan epitope, which is inhibited by RP215.	n-glycan	56-64	protein tyrosine kinase 2	Homo sapiens	27-30
30053729-4	2018	Kujigamberol decreased the molecular weight of intercellular adhesion molecule-1 (ICAM-1) by altering N-glycan modifications.	n-glycan	102-110	intercellular adhesion molecule 1	Homo sapiens	47-80
30053729-4	2018	Kujigamberol decreased the molecular weight of intercellular adhesion molecule-1 (ICAM-1) by altering N-glycan modifications.	n-glycan	102-110	intercellular adhesion molecule 1	Homo sapiens	82-88
30157878-6	2018	The canonical correlation analysis indicated that initial N-glycan structures, including GP4, GP6, GP9-12, GP14, GP17, GP18 and GP23, were significantly correlated with blood lipids, including total cholesterol, total triglycerides (TG) and low-density lipoprotein (r = 0.390, P < 0.001).	n-glycan	58-66	CD36 molecule	Homo sapiens	89-92
30157878-6	2018	The canonical correlation analysis indicated that initial N-glycan structures, including GP4, GP6, GP9-12, GP14, GP17, GP18 and GP23, were significantly correlated with blood lipids, including total cholesterol, total triglycerides (TG) and low-density lipoprotein (r = 0.390, P < 0.001).	n-glycan	58-66	glycoprotein VI platelet	Homo sapiens	94-97
30157878-6	2018	The canonical correlation analysis indicated that initial N-glycan structures, including GP4, GP6, GP9-12, GP14, GP17, GP18 and GP23, were significantly correlated with blood lipids, including total cholesterol, total triglycerides (TG) and low-density lipoprotein (r = 0.390, P < 0.001).	n-glycan	58-66	glycoprotein IX platelet	Homo sapiens	99-102
30017654-1	2018	Galactosylation as part of N-glycan processing is conducted by a set of beta-1,4-galactosyltransferases (B4GALTs), with B4GALT1 as the dominant isoenzyme for this reaction.	n-glycan	27-35	beta-1,4-galactosyltransferase 1	Cricetulus griseus	120-127
30017654-4	2018	Two model proteins were selected for this study to cover a large spectrum of possible N-glycan structures: erythropoietin and deamine-oxidase.	n-glycan	86-94	erythropoietin	Cricetulus griseus	107-121
29882469-2	2018	Disruption of OCH1 gene, which encodes an alpha-1,6-mannosyltransferase required for mannan-type N-glycan formation, is essential for the elimination of yeast-specific N-glycan structures.	n-glycan	97-105	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	14-18
29882469-2	2018	Disruption of OCH1 gene, which encodes an alpha-1,6-mannosyltransferase required for mannan-type N-glycan formation, is essential for the elimination of yeast-specific N-glycan structures.	n-glycan	97-105	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	42-71
29882469-2	2018	Disruption of OCH1 gene, which encodes an alpha-1,6-mannosyltransferase required for mannan-type N-glycan formation, is essential for the elimination of yeast-specific N-glycan structures.	n-glycan	168-176	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	14-18
29882469-2	2018	Disruption of OCH1 gene, which encodes an alpha-1,6-mannosyltransferase required for mannan-type N-glycan formation, is essential for the elimination of yeast-specific N-glycan structures.	n-glycan	168-176	alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	42-71
30120234-4	2018	We observe that naive and memory B cells express an N-glycan repertoire conferring strong binding to the immunoregulatory lectin galectin-9 (Gal-9).	n-glycan	52-60	galectin 9	Homo sapiens	129-139
30111543-5	2018	Conversely, similar analysis of the haptoglobin-hemoglobin (Hp-Hb) complex reveals the contrary effects of fucosylation and N-glycan branching on Hp-Hb interactions.	n-glycan	124-132	haptoglobin	Homo sapiens	36-47
30140003-6	2018	Interestingly, two aromatic rings sandwich the alpha1-6 branch of the acceptor N-glycan and restrain the global conformation, partly explaining the fine branch specificity of GnT-V.	n-glycan	79-87	adrenoceptor alpha 1D	Homo sapiens	47-55
30140003-6	2018	Interestingly, two aromatic rings sandwich the alpha1-6 branch of the acceptor N-glycan and restrain the global conformation, partly explaining the fine branch specificity of GnT-V.	n-glycan	79-87	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	175-180
30140003-8	2018	In summary, the acceptor-GnT-V complex structure suggests a catalytic mechanism, explains the previously observed inhibition of GnT-V by branching enzyme GnT-III, and provides a basis for the rational design of drugs targeting N-glycan branching.	n-glycan	227-235	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	25-30
30140003-8	2018	In summary, the acceptor-GnT-V complex structure suggests a catalytic mechanism, explains the previously observed inhibition of GnT-V by branching enzyme GnT-III, and provides a basis for the rational design of drugs targeting N-glycan branching.	n-glycan	227-235	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	128-133
30140003-8	2018	In summary, the acceptor-GnT-V complex structure suggests a catalytic mechanism, explains the previously observed inhibition of GnT-V by branching enzyme GnT-III, and provides a basis for the rational design of drugs targeting N-glycan branching.	n-glycan	227-235	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	154-161
30120234-4	2018	We observe that naive and memory B cells express an N-glycan repertoire conferring strong binding to the immunoregulatory lectin galectin-9 (Gal-9).	n-glycan	52-60	galectin 9	Homo sapiens	141-146
30008906-4	2018	Notably, fucosyltranferase 8 (FUT8), which is responsible for the addition of core-fucose to N-glycan, was significantly upregulated by miR-10b.	n-glycan	93-101	microRNA 10b	Homo sapiens	136-143
30084397-5	2018	This novel crystalline environment contributes to the observation that comparatively large parts of the N-glycan chains of HLE are defined by electron density.	n-glycan	104-112	elastase, neutrophil expressed	Homo sapiens	123-126
30072783-5	2018	The antigen target of A19 was identified as Erbb-2 and glycan analysis showed that A19 binds to a N-glycan epitope on the antigen.	n-glycan	98-106	immunoglobulin kappa variable 2-28	Homo sapiens	22-25
30072783-5	2018	The antigen target of A19 was identified as Erbb-2 and glycan analysis showed that A19 binds to a N-glycan epitope on the antigen.	n-glycan	98-106	erb-b2 receptor tyrosine kinase 2	Homo sapiens	44-50
30072783-5	2018	The antigen target of A19 was identified as Erbb-2 and glycan analysis showed that A19 binds to a N-glycan epitope on the antigen.	n-glycan	98-106	immunoglobulin kappa variable 2-28	Homo sapiens	83-86
29915530-5	2018	Furthermore, deglycosylation and lectin-based analysis revealed that GluN3A subunits contain extensively modified N-glycan structures, including hybrid/complex forms of N-glycans.	n-glycan	114-122	glutamate ionotropic receptor NMDA type subunit 3A	Homo sapiens	69-75
29733746-4	2018	In particular, absence of core fucose on the Fc N-glycan has been shown to increase IgG1 Fc binding affinity to the FcgammaRIIIa present on immune effector cells such as natural killer cells and lead to enhanced ADCC activity.	n-glycan	48-56	Fc gamma receptor IIIa	Homo sapiens	116-128
29725729-2	2018	Each glycoprotein may have multiple glycoforms, and cancer-related ones can be only some specific glycoforms which have much higher sensitivity and specificity; for example, AFP glycoform AFP-L3 with N-glycan of 01Y(61F)41Y41M(31M41Y41L41S61M41Y41L41S is of bigger diagnostic value for hepatocellular carcinoma than total AFP (i.e., combination of all glycoforms).	n-glycan	200-208	alpha fetoprotein	Homo sapiens	174-177
29725729-2	2018	Each glycoprotein may have multiple glycoforms, and cancer-related ones can be only some specific glycoforms which have much higher sensitivity and specificity; for example, AFP glycoform AFP-L3 with N-glycan of 01Y(61F)41Y41M(31M41Y41L41S61M41Y41L41S is of bigger diagnostic value for hepatocellular carcinoma than total AFP (i.e., combination of all glycoforms).	n-glycan	200-208	alpha fetoprotein	Homo sapiens	188-191
29725729-2	2018	Each glycoprotein may have multiple glycoforms, and cancer-related ones can be only some specific glycoforms which have much higher sensitivity and specificity; for example, AFP glycoform AFP-L3 with N-glycan of 01Y(61F)41Y41M(31M41Y41L41S61M41Y41L41S is of bigger diagnostic value for hepatocellular carcinoma than total AFP (i.e., combination of all glycoforms).	n-glycan	200-208	alpha fetoprotein	Homo sapiens	188-191
29575162-5	2018	Here we present an on-line CE/LIF/MS N-glycan analysis workflow that incorporates the fluorescent Teal  dye and an electrokinetic pump-based nanospray sheath liquid capillary electrophoresis/mass spectrometry (CE/MS) ion source.	n-glycan	37-45	LIF interleukin 6 family cytokine	Homo sapiens	30-33
29452367-11	2018	These results suggest that this N-glycan of POFUT1 is not required for its proper enzymatic function, and that the p.Ser162Leu mutation of POFUT1 likely causes global developmental delay, microcephaly with vascular and cardiac defects.	n-glycan	32-40	protein O-fucosyltransferase 1	Homo sapiens	44-50
29401627-8	2018	We showed that mDectin-1, mDectin-2, and SIGN-R1 are decorated by N-glycan structures that can be recognized by the carbohydrate recognition domain of Gal-3.	n-glycan	66-74	C-type lectin domain family 7, member a	Mus musculus	15-24
29401627-8	2018	We showed that mDectin-1, mDectin-2, and SIGN-R1 are decorated by N-glycan structures that can be recognized by the carbohydrate recognition domain of Gal-3.	n-glycan	66-74	C-type lectin domain family 4, member n	Mus musculus	26-35
29401627-8	2018	We showed that mDectin-1, mDectin-2, and SIGN-R1 are decorated by N-glycan structures that can be recognized by the carbohydrate recognition domain of Gal-3.	n-glycan	66-74	CD209b antigen	Mus musculus	41-48
29401627-8	2018	We showed that mDectin-1, mDectin-2, and SIGN-R1 are decorated by N-glycan structures that can be recognized by the carbohydrate recognition domain of Gal-3.	n-glycan	66-74	galectin 3	Homo sapiens	151-156
29549127-6	2018	N-Glycan deletion on beta4-integrin impaired beta4-dependent cancer cell migration, invasion, and growth in vitro and diminished tumorigenesis and proliferation in vivo The reduced abilities of beta4-integrin were accompanied with decreased phosphoinositol-3 kinase (PI3K)/Akt signals and were restored by the overexpression of the constitutively active p110 PI3K subunit.	n-glycan	0-8	tubulin beta 3 class III	Homo sapiens	21-26
29549127-6	2018	N-Glycan deletion on beta4-integrin impaired beta4-dependent cancer cell migration, invasion, and growth in vitro and diminished tumorigenesis and proliferation in vivo The reduced abilities of beta4-integrin were accompanied with decreased phosphoinositol-3 kinase (PI3K)/Akt signals and were restored by the overexpression of the constitutively active p110 PI3K subunit.	n-glycan	0-8	tubulin beta 3 class III	Homo sapiens	45-50
29549127-6	2018	N-Glycan deletion on beta4-integrin impaired beta4-dependent cancer cell migration, invasion, and growth in vitro and diminished tumorigenesis and proliferation in vivo The reduced abilities of beta4-integrin were accompanied with decreased phosphoinositol-3 kinase (PI3K)/Akt signals and were restored by the overexpression of the constitutively active p110 PI3K subunit.	n-glycan	0-8	tubulin beta 3 class III	Homo sapiens	45-50
29549127-6	2018	N-Glycan deletion on beta4-integrin impaired beta4-dependent cancer cell migration, invasion, and growth in vitro and diminished tumorigenesis and proliferation in vivo The reduced abilities of beta4-integrin were accompanied with decreased phosphoinositol-3 kinase (PI3K)/Akt signals and were restored by the overexpression of the constitutively active p110 PI3K subunit.	n-glycan	0-8	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	Homo sapiens	241-265
29549127-6	2018	N-Glycan deletion on beta4-integrin impaired beta4-dependent cancer cell migration, invasion, and growth in vitro and diminished tumorigenesis and proliferation in vivo The reduced abilities of beta4-integrin were accompanied with decreased phosphoinositol-3 kinase (PI3K)/Akt signals and were restored by the overexpression of the constitutively active p110 PI3K subunit.	n-glycan	0-8	AKT serine/threonine kinase 1	Homo sapiens	273-276
29549127-9	2018	Furthermore, galectin-3 knockdown by shRNA suppressed beta4-integrin N-glycan-mediated tumorigenesis.	n-glycan	69-77	galectin 3	Homo sapiens	13-23
29549127-9	2018	Furthermore, galectin-3 knockdown by shRNA suppressed beta4-integrin N-glycan-mediated tumorigenesis.	n-glycan	69-77	tubulin beta 3 class III	Homo sapiens	54-59
29881382-6	2018	These antibodies targeted the N-glycan "hole" naturally present on the BG505 Env proximal to residues at positions 230, 241, and 289.	n-glycan	30-38	endogenous retrovirus group K member 20	Homo sapiens	77-80
29743543-4	2018	Mgat3 is a key glycosyltransferase in the synthesis of the bisecting (beta1,4GlcNAc branching) N-glycan structure.	n-glycan	95-103	mannoside acetylglucosaminyltransferase 3	Mus musculus	0-5
29743543-7	2018	Collectively, these results indicate that miR-23a might increase the metastatic potential of mouse HCC by affecting the branch formation of N-glycan chains presented on the cell surface through the targeting of the glycosyltransferase Mgat3.	n-glycan	140-148	microRNA 23a	Mus musculus	42-49
29743543-7	2018	Collectively, these results indicate that miR-23a might increase the metastatic potential of mouse HCC by affecting the branch formation of N-glycan chains presented on the cell surface through the targeting of the glycosyltransferase Mgat3.	n-glycan	140-148	mannoside acetylglucosaminyltransferase 3	Mus musculus	235-240
29409894-6	2018	However, mutation in EBS3, which is required for the formation of the branched N-glycan precursor, suppressed the salt-sensitive phenotype of mns1 mns2 double mutant.	n-glycan	79-87	Alg9-like mannosyltransferase family	Arabidopsis thaliana	21-25
29409894-6	2018	However, mutation in EBS3, which is required for the formation of the branched N-glycan precursor, suppressed the salt-sensitive phenotype of mns1 mns2 double mutant.	n-glycan	79-87	alpha-mannosidase 1	Arabidopsis thaliana	142-146
29409894-6	2018	However, mutation in EBS3, which is required for the formation of the branched N-glycan precursor, suppressed the salt-sensitive phenotype of mns1 mns2 double mutant.	n-glycan	79-87	alpha-mannosidase 2	Arabidopsis thaliana	147-151
29769533-1	2018	Furin cleavage of the HIV envelope glycoprotein is an essential step for cell entry that enables formation of well-folded, native-like glycosylated trimers, releases constraints on the fusion peptide, and limits enzymatic processing of the N-glycan shield.	n-glycan	240-248	furin, paired basic amino acid cleaving enzyme	Homo sapiens	0-5
29475941-8	2018	In triple KO (MAN1A1, MAN1A2, and MAN1B1) cells, Man9GlcNAc2 and Man8GlcNAc2 were the major N-glycan structures.	n-glycan	92-100	mannosidase alpha class 1A member 1	Homo sapiens	14-20
29475941-8	2018	In triple KO (MAN1A1, MAN1A2, and MAN1B1) cells, Man9GlcNAc2 and Man8GlcNAc2 were the major N-glycan structures.	n-glycan	92-100	mannosidase alpha class 1A member 2	Homo sapiens	22-28
29475941-8	2018	In triple KO (MAN1A1, MAN1A2, and MAN1B1) cells, Man9GlcNAc2 and Man8GlcNAc2 were the major N-glycan structures.	n-glycan	92-100	mannosidase alpha class 1B member 1	Homo sapiens	34-40
29502191-2	2018	N-acetylglucosaminyltransferase III (GnT-III) is known to catalyze N-glycan "bisection" and thereby modulate the formation of highly branched complex structures within the Golgi apparatus.	n-glycan	67-75	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-35
29642865-0	2018	Serum leucine-rich alpha-2-glycoprotein-1 with fucosylated triantennary N-glycan: a novel colorectal cancer marker.	n-glycan	72-80	leucine rich alpha-2-glycoprotein 1	Homo sapiens	6-41
29642865-4	2018	RESULTS: Leucine-rich alpha-2-glycoprotein-1 with fucosylated triantennary N-glycan (LRG-FTG) was identified as CRC marker after evaluating 30,000 candidate glycopeptide peaks.	n-glycan	75-83	leucine rich alpha-2-glycoprotein 1	Homo sapiens	9-44
29642865-4	2018	RESULTS: Leucine-rich alpha-2-glycoprotein-1 with fucosylated triantennary N-glycan (LRG-FTG) was identified as CRC marker after evaluating 30,000 candidate glycopeptide peaks.	n-glycan	75-83	leucine rich alpha-2-glycoprotein 1	Homo sapiens	85-88
29502191-2	2018	N-acetylglucosaminyltransferase III (GnT-III) is known to catalyze N-glycan "bisection" and thereby modulate the formation of highly branched complex structures within the Golgi apparatus.	n-glycan	67-75	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	37-44
29502191-8	2018	We found that the overexpression of GnT-III in melanoma leads to the modification of a broad range of N-glycan types by the introduction of the "bisecting" GlcNAc residue with highly branched complex structures among them.	n-glycan	102-110	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	36-43
29330305-6	2018	Of note, these differences in CD16a N-glycan composition affected antibody binding: CD16a with oligomannose N-glycans bound IgG1 Fc with 12-fold greater affinity than did CD16a having primarily complex-type and highly branched N-glycans.	n-glycan	36-44	Fc gamma receptor IIIa	Homo sapiens	30-34
29593217-2	2018	Developing bNAbs with increased efficacy requires understanding how antibodies interact with the native oligomannose and complex-type N-glycan shield that hides most protein epitopes on HIV-1 envelope (Env).	n-glycan	134-142	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	202-205
29466327-5	2018	We found that seven phospholipids mediate many of the inter-subunit interactions, and an Stt3 N-glycan mediates interactions with Wbp1 and Swp1 in the lumen.	n-glycan	94-102	dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3	Saccharomyces cerevisiae S288C	89-93
29466327-5	2018	We found that seven phospholipids mediate many of the inter-subunit interactions, and an Stt3 N-glycan mediates interactions with Wbp1 and Swp1 in the lumen.	n-glycan	94-102	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	130-134
29466327-5	2018	We found that seven phospholipids mediate many of the inter-subunit interactions, and an Stt3 N-glycan mediates interactions with Wbp1 and Swp1 in the lumen.	n-glycan	94-102	dolichyl-diphosphooligosaccharide-protein glycotransferase	Saccharomyces cerevisiae S288C	139-143
29562594-5	2018	The CMG2-Fc N-glycan profile was determined using LC-MS/MS with a targeted dynamic multiple reaction monitoring (MRM) method.	n-glycan	12-20	ANTXR cell adhesion molecule 2	Homo sapiens	4-8
29330305-6	2018	Of note, these differences in CD16a N-glycan composition affected antibody binding: CD16a with oligomannose N-glycans bound IgG1 Fc with 12-fold greater affinity than did CD16a having primarily complex-type and highly branched N-glycans.	n-glycan	36-44	Fc gamma receptor IIIa	Homo sapiens	30-35
29330305-6	2018	Of note, these differences in CD16a N-glycan composition affected antibody binding: CD16a with oligomannose N-glycans bound IgG1 Fc with 12-fold greater affinity than did CD16a having primarily complex-type and highly branched N-glycans.	n-glycan	36-44	Fc gamma receptor IIIa	Homo sapiens	84-89
29330305-9	2018	Furthermore, our study provides critical evidence that cell lineage determines CD16a N-glycan composition and antibody-binding affinity.	n-glycan	85-93	Fc gamma receptor IIIa	Homo sapiens	79-84
29178403-0	2018	N-glycan engineering of a plant-produced anti-CD20-hIL-2 immunocytokine significantly enhances its effector functions.	n-glycan	0-8	keratin 20	Homo sapiens	46-50
29523796-3	2018	Using a combination of N-glycan engineering for enhanced protease resistance and improved solubility, Fc fusion for further half-life extension, and a single point mutation for improving manufacturability in Chinese Hamster Ovary cells, we created a novel FGF21 analogue, Fc-FGF21[R19V][N171] or PF-06645849, with substantially improved solubility and stability profile that is compatible with subcutaneous (SC) administration.	n-glycan	23-31	fibroblast growth factor 21	Cricetulus griseus	256-261
29178403-0	2018	N-glycan engineering of a plant-produced anti-CD20-hIL-2 immunocytokine significantly enhances its effector functions.	n-glycan	0-8	interleukin 2	Homo sapiens	51-56
29237727-6	2018	To demonstrate the precision of the approach, we also profiled N-glycopeptides from the mutant (xylt) of beta-1,2-xylosyltransferase, an enzyme in the N-glycan biosynthetic pathway.	n-glycan	151-159	beta-1,2-xylosyltransferase	Arabidopsis thaliana	105-132
29396160-0	2018	Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity.	n-glycan	67-75	interleukin 10	Homo sapiens	0-14
29396160-0	2018	Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity.	n-glycan	67-75	CD8a molecule	Homo sapiens	33-36
29396160-5	2018	Mechanistically, we showed that IL-10 induced the expression of Mgat5, a glycosyltransferase that enhances N-glycan branching on surface glycoproteins.	n-glycan	107-115	interleukin 10	Homo sapiens	32-37
29396160-5	2018	Mechanistically, we showed that IL-10 induced the expression of Mgat5, a glycosyltransferase that enhances N-glycan branching on surface glycoproteins.	n-glycan	107-115	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	64-69
29255114-6	2018	Calnexin was specifically associated with GPI-APs, dependent on N-glycan and GPI moieties, and assisted efficient GPI-inositol deacylation by PGAP1.	n-glycan	64-72	calnexin	Homo sapiens	0-8
29396160-6	2018	Increased N-glycan branching on CD8+ T cells promoted the formation of a galectin 3-mediated membrane lattice, which restricted the interaction of key glycoproteins, ultimately increasing the antigenic threshold required for T cell activation.	n-glycan	10-18	CD8a molecule	Homo sapiens	32-35
29396160-6	2018	Increased N-glycan branching on CD8+ T cells promoted the formation of a galectin 3-mediated membrane lattice, which restricted the interaction of key glycoproteins, ultimately increasing the antigenic threshold required for T cell activation.	n-glycan	10-18	galectin 3	Homo sapiens	73-83
29157724-6	2018	We identified 58 N-glycan compositions from lung adenocarcinoma FFPE samples, 51 of which were further used for MSn-based structure prediction.	n-glycan	17-25	moesin	Homo sapiens	112-115
29434598-4	2018	Loss of core fucosyltransferase (Fut8), the sole enzyme for catalyzing the core fucosylation of N-glycan, significantly reduced CD4+ T cell activation and ameliorated the experimental autoimmune encephalomyelitis-induced syndrome in Fut8-/- mice.	n-glycan	96-104	fucosyltransferase 8	Mus musculus	33-37
29145098-0	2018	A novel, simplified strategy of relative quantification N-glycan: Quantitative glycomics using electrospray ionization mass spectrometry through the stable isotopic labeling by transglycosylation reaction of mutant enzyme Endo-M-N175Q.	n-glycan	56-64	mannosidase endo-alpha	Homo sapiens	222-226
29273683-9	2018	Thus, the presence and composition of an N-glycan in this conserved position both appear to influence the steroid binding of CBG.	n-glycan	41-49	serpin family A member 6	Homo sapiens	125-128
29434598-4	2018	Loss of core fucosyltransferase (Fut8), the sole enzyme for catalyzing the core fucosylation of N-glycan, significantly reduced CD4+ T cell activation and ameliorated the experimental autoimmune encephalomyelitis-induced syndrome in Fut8-/- mice.	n-glycan	96-104	fucosyltransferase 8	Mus musculus	233-237
29719608-0	2018	c-Jun-dependent beta3GnT8 promotes tumorigenesis and metastasis of hepatocellular carcinoma by inducing CD147 glycosylation and altering N-glycan patterns.	n-glycan	137-145	Jun proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	0-5
29719608-0	2018	c-Jun-dependent beta3GnT8 promotes tumorigenesis and metastasis of hepatocellular carcinoma by inducing CD147 glycosylation and altering N-glycan patterns.	n-glycan	137-145	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	Homo sapiens	16-25
30185708-4	2018	We recently illustrated that the accumulation of mutant CALR in the Golgi apparatus and its N-glycan binding capacity are needed for its tumorigenic capacity, including the interaction and activation of MPL.	n-glycan	92-100	calreticulin	Homo sapiens	56-60
30484244-5	2018	In this chapter, the methods and approaches to robustly and reproducibly generate two-dimensional N-glycan tissue maps by MALDI-MSI workflows are summarized.	n-glycan	98-106	RB binding protein 4, chromatin remodeling factor	Homo sapiens	128-131
31131224-5	2018	Next, we detected that transition to androgen unresponsiveness is accompanied by downregulation of N-acetylglucosaminyltransferase-III (MGAT3), the enzyme that competes with MGAT5 for anti-metastatic N-glycan branching.	n-glycan	200-208	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	99-134
31131224-5	2018	Next, we detected that transition to androgen unresponsiveness is accompanied by downregulation of N-acetylglucosaminyltransferase-III (MGAT3), the enzyme that competes with MGAT5 for anti-metastatic N-glycan branching.	n-glycan	200-208	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	136-141
31131224-5	2018	Next, we detected that transition to androgen unresponsiveness is accompanied by downregulation of N-acetylglucosaminyltransferase-III (MGAT3), the enzyme that competes with MGAT5 for anti-metastatic N-glycan branching.	n-glycan	200-208	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	174-179
30637701-7	2018	Apart from participating in N-glycan biosynthesis, DPMS is essential for the synthesis of GPI anchor as well as for O- and C-mannosylation of proteins.	n-glycan	28-36	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Bos taurus	51-55
30185708-4	2018	We recently illustrated that the accumulation of mutant CALR in the Golgi apparatus and its N-glycan binding capacity are needed for its tumorigenic capacity, including the interaction and activation of MPL.	n-glycan	92-100	MPL proto-oncogene, thrombopoietin receptor	Homo sapiens	203-206
27314244-9	2017	A major alpha2-6-sialylated N-glycan structure detected in adipose-derived hMSCs was that of mono-sialylated biantennary N-glycan.	n-glycan	28-36	immunoglobulin binding protein 1	Homo sapiens	8-16
29090617-2	2017	Here, we first prepared anti-HER2 mAbs having two core-fucosylated N-glycan chains with the single G2F, G1aF, G1bF, or G0F structure, together with those having two N-glycan chains with a single non-core-fucosylated corresponding structure for comparison, and determined their biological activities.	n-glycan	67-75	erb-b2 receptor tyrosine kinase 2	Homo sapiens	29-33
29090617-5	2017	These results indicate that the presence of a core-fucose residue in the N-glycan suppresses the binding to the Fc-receptor and the induction of ADCC of anti-HER2 mAbs.	n-glycan	73-81	erb-b2 receptor tyrosine kinase 2	Homo sapiens	158-162
27314244-9	2017	A major alpha2-6-sialylated N-glycan structure detected in adipose-derived hMSCs was that of mono-sialylated biantennary N-glycan.	n-glycan	121-129	immunoglobulin binding protein 1	Homo sapiens	8-16
28556996-0	2017	Semi-high-throughput isolation and N-glycan analysis of human fibrinogen using monolithic supports bearing monoclonal anti-human fibrinogen antibodies.	n-glycan	35-43	fibrinogen beta chain	Homo sapiens	62-72
28973127-8	2017	The X-ray crystallographic structure reveals that two Orysata lectins bind to one biantennary N-glycan (2:1 binding) where one lectin binds to mannose of the alpha1-3 branch, while the other interacts with an N-acetylglucosamine of the alpha1-6 branch.	n-glycan	94-102	adrenoceptor alpha 1D	Homo sapiens	158-166
28973127-8	2017	The X-ray crystallographic structure reveals that two Orysata lectins bind to one biantennary N-glycan (2:1 binding) where one lectin binds to mannose of the alpha1-3 branch, while the other interacts with an N-acetylglucosamine of the alpha1-6 branch.	n-glycan	94-102	adrenoceptor alpha 1D	Homo sapiens	236-244
28973127-11	2017	Binding free energies calculated separately for alpha1-3 and alpha1-6 branches of each N-glycan suggest both branches can bind to Orysata.	n-glycan	87-95	adrenoceptor alpha 1D	Homo sapiens	48-69
28474843-10	2017	In contrast, N-glycan derived from Bla g 2 significantly inhibited histamine release and IL-4 production from basophils passively sensitized with serum from cockroach allergic subjects.	n-glycan	13-21	interleukin 4	Homo sapiens	89-93
28942847-7	2017	Noteworthy, this endogenous lectin displayed similar sugar-binding specificity to that of TL and therefore could be important in either the N-glycan mediated endocytosis or parasite adhesion to host cells.	n-glycan	140-148	LTL	Solanum lycopersicum	28-34
29119347-0	2017	N-glycan structures and downstream mannose-phosphorylation of plant recombinant human alpha-L-iduronidase: toward development of enzyme replacement therapy for mucopolysaccharidosis I.	n-glycan	0-8	alpha-L-iduronidase	Homo sapiens	86-105
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	n-glycan	38-46	alpha-L-iduronidase	Homo sapiens	218-222
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	n-glycan	38-46	alpha-L-iduronidase	Homo sapiens	239-243
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	n-glycan	76-84	alpha-L-iduronidase	Homo sapiens	218-222
29119347-3	2017	Both strategies effectively prevented N-glycan maturation and the resultant N-glycan structures on the consensus sites for N-glycosylation of the human enzyme revealed high-mannose N-glycans of predominantly Man5 (cgl-IDUA) or Man6-8 (gm1-IDUA) structures.	n-glycan	76-84	alpha-L-iduronidase	Homo sapiens	239-243
28956227-9	2017	Structural modeling analysis based on putative structures derived from bacterial-originated CD39 domain proteins suggests that N-glycan modifications at Asn149 next to ACR2 and/or Asn454, N-terminal to ACR5 have critical roles in regulating the catalytic pocket of NTPDase3/CD39L3.	n-glycan	127-135	ectonucleoside triphosphate diphosphohydrolase 1	Homo sapiens	92-96
28956227-9	2017	Structural modeling analysis based on putative structures derived from bacterial-originated CD39 domain proteins suggests that N-glycan modifications at Asn149 next to ACR2 and/or Asn454, N-terminal to ACR5 have critical roles in regulating the catalytic pocket of NTPDase3/CD39L3.	n-glycan	127-135	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	265-273
28956227-9	2017	Structural modeling analysis based on putative structures derived from bacterial-originated CD39 domain proteins suggests that N-glycan modifications at Asn149 next to ACR2 and/or Asn454, N-terminal to ACR5 have critical roles in regulating the catalytic pocket of NTPDase3/CD39L3.	n-glycan	127-135	ectonucleoside triphosphate diphosphohydrolase 3	Homo sapiens	274-280
28647147-8	2017	The applicability of this use of stationary zones of enzyme and lectin in capillary electrophoresis is demonstrated with the identification of beta(1-3)-linked galactose in N-glycan.	n-glycan	173-181	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	143-151
28922740-8	2017	Combining the knowledge gained from the PglB structures and mutagenesis studies, we propose a function for the DGGK motif in affecting the binding of the undecaprenyl-pyrophosphate glycan donor substrate that subsequently influences N-glycan and fOS production.	n-glycan	233-241	epiphycan	Homo sapiens	40-44
28829050-5	2017	We discovered that THP engages the inhibitory neutrophil receptor sialic acid-binding Ig-like lectin-9 (Siglec-9), and mouse functional ortholog Siglec-E, in a manner dependent on sialic acid on its N-glycan moieties.	n-glycan	199-207	uromodulin	Mus musculus	19-22
29062024-0	2017	Conformational effects of N-glycan core fucosylation of immunoglobulin G Fc region on its interaction with Fcgamma receptor IIIa.	n-glycan	26-34	Fc gamma receptor IIIa	Homo sapiens	107-128
28978918-4	2017	High-mannose glycoform preferentially samples conformations that are more competent to FcgammaRIIIa binding, compared to the truncated glycoforms, suggesting a role of IgG1 Fc N-glycan in optimizing the interface with the Fc receptor for efficient binding.	n-glycan	176-184	Fc gamma receptor IIIa	Homo sapiens	87-99
28931878-5	2017	From 277 patients with rheumatoid arthritis (RA) and 141 healthy individuals, we also identify N-glycan biomarkers for the classification of both rheumatoid factor (RF)-positive and negative RA patients, as well as anti-citrullinated protein antibodies (ACPA)-positive and negative RA patients.	n-glycan	95-103	proteinase 3	Homo sapiens	254-258
28820257-8	2017	We then introduced the optimized-enhanced aromatic sequons into other glycoproteins and observed an enhancement in N-glycan occupancy that was further supported by modeling the high-affinity interaction between the optimized sequence on hCD2ad and a human oligosaccharyltransferase (OST) subunit.	n-glycan	115-123	CD2 molecule	Homo sapiens	237-241
28820257-8	2017	We then introduced the optimized-enhanced aromatic sequons into other glycoproteins and observed an enhancement in N-glycan occupancy that was further supported by modeling the high-affinity interaction between the optimized sequence on hCD2ad and a human oligosaccharyltransferase (OST) subunit.	n-glycan	115-123	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	256-281
28820257-8	2017	We then introduced the optimized-enhanced aromatic sequons into other glycoproteins and observed an enhancement in N-glycan occupancy that was further supported by modeling the high-affinity interaction between the optimized sequence on hCD2ad and a human oligosaccharyltransferase (OST) subunit.	n-glycan	115-123	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	Homo sapiens	283-286
28873000-1	2017	Podocalyxin is a CD34-related type I transmembrane protein that is highly glycosylated with N-glycan, O-glycan, and keratan sulfate.	n-glycan	92-100	podocalyxin like	Homo sapiens	0-11
28902916-5	2017	We selectively deleted potential N-glycan sites (PNGS) proximal to the CD4bs on well-ordered clade C 16055 native flexibly linked (NFL) trimers to potentially increase recognition by naive B cells in vivo.	n-glycan	33-41	T-cell surface glycoprotein CD4	Oryctolagus cuniculus	71-74
28829594-0	2017	CD22 Ligands on a Natural N-Glycan Scaffold Efficiently Deliver Toxins to B-Lymphoma Cells.	n-glycan	26-34	CD22 molecule	Homo sapiens	0-4
28902916-7	2017	Using a panel of CD4bs-directed bNAbs, we demonstrated improved accessibility of the CD4bs on the N-glycan-deleted trimer variants.	n-glycan	98-106	T-cell surface glycoprotein CD4	Oryctolagus cuniculus	17-20
28733331-4	2017	In the present study, we analysed N-glycosylation sites of FNDC5 and found that two potential N-glycosylation sites (Asn36 and Asn81) could indeed be occupied by N-glycan.	n-glycan	162-170	fibronectin type III domain containing 5	Homo sapiens	59-64
28729420-2	2017	Previously, intensive in vitro studies with crude extract or purified enzyme concluded that the attachment of a GlcNAc on the alpha1,3 mannose arm of N-glycan is essential for FUT8-catalyzed core fucosylation.	n-glycan	150-158	fucosyltransferase 8	Homo sapiens	176-180
28729420-7	2017	Interestingly, when placed in the V3 polypeptide context, a mature bi-antennary complex-type N-glycan also could be core-fucosylated by FUT8, albeit at much lower efficiency than the Man5GlcNAc2 peptide.	n-glycan	93-101	fucosyltransferase 8	Homo sapiens	136-140
28615211-10	2017	Our results show that EBOV GP/VSVDeltaG pseudovirions serve as a successful vaccination platform in a rodent model of Ebola virus disease and that GP1 N-glycan loss does not influence immunogenicity or vaccination success.IMPORTANCE The West African Ebola virus epidemic was the largest to date, with more than 28,000 people infected.	n-glycan	151-159	GTP binding protein 1	Mus musculus	147-150
28547344-6	2017	These results suggested that the control of BmFDL expression by its shRNA in silkworms caused the modification of its N-glycan synthetic pathway, which may lead to the alteration of N-glycans in the expressed recombinant proteins.	n-glycan	118-126	fused lobes	Bombyx mori	44-49
28547344-7	2017	CONCLUSIONS: Suppression of BmFDL gene expression by shRNA is not sufficient to synthesize complex N-glycans in silkworm larvae but can modify the N-glycan synthetic pathway.	n-glycan	99-107	fused lobes	Bombyx mori	28-33
28389847-4	2017	A total of 40, 47, 29, and 33 N-glycan peaks were identified and annotated from HV, HB, HC, and HCC groups, respectively.	n-glycan	30-38	HCC	Homo sapiens	96-99
28785006-7	2017	The structure revealed that ciA-C2 partially occupies the SV2-binding site on HCA1, causing direct interference of HCA1 interaction with both the N-glycan and peptide-moiety of SV2.	n-glycan	146-154	nuclear receptor coactivator 5	Homo sapiens	28-31
28785006-7	2017	The structure revealed that ciA-C2 partially occupies the SV2-binding site on HCA1, causing direct interference of HCA1 interaction with both the N-glycan and peptide-moiety of SV2.	n-glycan	146-154	synaptic vesicle glycoprotein 2A	Homo sapiens	58-61
28785006-7	2017	The structure revealed that ciA-C2 partially occupies the SV2-binding site on HCA1, causing direct interference of HCA1 interaction with both the N-glycan and peptide-moiety of SV2.	n-glycan	146-154	HCA1	Homo sapiens	78-82
28785006-7	2017	The structure revealed that ciA-C2 partially occupies the SV2-binding site on HCA1, causing direct interference of HCA1 interaction with both the N-glycan and peptide-moiety of SV2.	n-glycan	146-154	HCA1	Homo sapiens	115-119
28554385-1	2017	Terminal sialic acids on N-glycan of recombinant human erythropoietin are very important for in vivo half-life, as this glycoprotein has three N-glycosylation sites.	n-glycan	25-33	erythropoietin	Homo sapiens	55-69
28535302-0	2017	Inhibition of N-acetylglucosaminyltransferase V enhances the cetuximab-induced radiosensitivity of nasopharyngeal carcinoma cells likely through EGFR N-glycan alterations.	n-glycan	150-158	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	14-47
28535302-0	2017	Inhibition of N-acetylglucosaminyltransferase V enhances the cetuximab-induced radiosensitivity of nasopharyngeal carcinoma cells likely through EGFR N-glycan alterations.	n-glycan	150-158	epidermal growth factor receptor	Homo sapiens	145-149
28614667-5	2017	N-Glycan-free CTR ECD produced in Escherichia coli exhibited ~10-fold lower peptide affinity than CTR ECD produced in HEK293T cells, which yield complex N-glycans, or in HEK293S GnTI- cells, which yield core N-glycans (Man5GlcNAc2).	n-glycan	0-8	calcitonin receptor	Homo sapiens	14-17
28482115-4	2017	The activity of FLA4 was resistant against deletion of the amino-proximal fasciclin 1 domain and was unaffected by removal of the GPI-modification signal, a highly conserved N-glycan or the deletion of predicted O-glycosylation sites.	n-glycan	174-182	Fasciclin-like arabinogalactan family protein	Arabidopsis thaliana	16-20
28765651-0	2017	CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition.	n-glycan	73-81	CD14 antigen	Mus musculus	0-4
28765651-0	2017	CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition.	n-glycan	73-81	toll-like receptor 2	Mus musculus	21-25
29179433-12	2017	Site-directed mutagenesis of the N-glycan-modified residues in Skl abolished its antioxidant activity, suggesting that these N-glycan moieties are important features that interact with FGH.	n-glycan	33-41	esterase D	Homo sapiens	185-188
29179433-12	2017	Site-directed mutagenesis of the N-glycan-modified residues in Skl abolished its antioxidant activity, suggesting that these N-glycan moieties are important features that interact with FGH.	n-glycan	125-133	esterase D	Homo sapiens	185-188
28634480-6	2017	Addition of terminal galactose to the N-glycan specifically improved binding of C1q without changing antigen- and FcgammaRIIIa-binding affinities of IgG isotypes.	n-glycan	38-46	complement C1q A chain	Homo sapiens	80-83
28467637-5	2017	Deletion of the N-glycan at the N-terminus rather than Asn187 showed decreased effects on isoproterenol-promoted G-protein-dependent signaling, beta-arrestin2 recruitment, and receptor internalization.	n-glycan	16-24	arrestin beta 2	Homo sapiens	144-158
28613884-7	2017	We used a combination of NMR and 1 mus all-atom computational simulations to identify unexpected contacts between the N45 N-glycan and CD16A polypeptide residues.	n-glycan	122-130	Fc gamma receptor IIIa	Homo sapiens	135-140
28426178-5	2017	CE-LIF is one of the typical techniques for N-glycan analysis due to its high separation efficiency.	n-glycan	44-52	LIF interleukin 6 family cytokine	Homo sapiens	3-6
28363873-11	2017	N-glycan analysis revealed the presence of high-mannose N-glycans on gnt1-GAA.	n-glycan	0-8	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	69-73
28397166-5	2017	Assignment of the IgG N-glycan structures was made through branching pattern analysis by MSn with high-throughput.	n-glycan	22-30	moesin	Homo sapiens	89-92
28366632-0	2017	Inhibition of N-glycan processing modulates the network of EDEM3 interactors.	n-glycan	14-22	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	59-64
28366632-1	2017	We present here data on EDEM3 network of ER resident interactors and the changes induced upon this network by perturbing the early ER N-glycan processing with mannosidase and glucosidase inhibitors.	n-glycan	134-142	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	24-29
28366632-3	2017	We further show that this ER interaction network changes in both content and abundance upon treatment with kifunensine (kif) and N-butyldeoxynojirimycin (NB-DNJ) which suggests that when interfering with the N-glycan processing pathway, the functional complexes involving EDEM3 adapt to maintain the cellular homeostasis.	n-glycan	208-216	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	272-277
28366632-7	2017	In addition, the results indicate that this network of EDEM3 interactors is highly sensitive to interfering with early ER N-glycan processing.	n-glycan	122-130	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	55-60
28241428-2	2017	The aim of this study to examine whether the serum PCa-associated alpha2,3-linked sialyl N-glycan-carrying PSA (S2,3PSA) ratio measured by automated micro-total immunoassay systems (muTAS system) can be applied as a diagnostic marker of PCa.	n-glycan	89-97	kallikrein related peptidase 3	Homo sapiens	107-110
28280844-8	2017	Combining the isomer resolution of HPAE with MS2 permitted thorough N-glycan annotation and led to characterization of 17 new structures from glycoproteins with challenging glycan profiles.	n-glycan	68-76	MS2	Homo sapiens	45-48
28101612-5	2017	N-glycan profile analysis of cell wall mannoproteins and a secretory recombinant protein produced in mutants showed that the MNN14 gene, an MNN4 paralog with unknown function, is essential for N-glycan mannosylphosphorylation.	n-glycan	0-8	Mnn4p	Saccharomyces cerevisiae S288C	140-144
28101612-5	2017	N-glycan profile analysis of cell wall mannoproteins and a secretory recombinant protein produced in mutants showed that the MNN14 gene, an MNN4 paralog with unknown function, is essential for N-glycan mannosylphosphorylation.	n-glycan	193-201	Mnn4p	Saccharomyces cerevisiae S288C	140-144
28101612-6	2017	Double disruption of MNN4 and MNN14 genes was enough to eliminate N-glycan mannosylphosphorylation.	n-glycan	66-74	Mnn4p	Saccharomyces cerevisiae S288C	21-25
28280963-12	2017	N-glycan units were constructed; moreover, EPO protein was glycosylated at potential glycosylation amino acid residue sites.	n-glycan	0-8	erythropoietin	Homo sapiens	43-46
28469195-7	2017	The obtained N-glycan structure was dependent on the promoters used for coexpression of hGnT II or hGalT I.	n-glycan	13-21	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	88-95
28019699-4	2017	Molecular dynamics simulations were performed to characterize the conformational preferences of the monomeric and dimeric forms of the EGFR extracellular domain upon binding to EGF in the presence and absence of N-glycan moieties.	n-glycan	212-220	epidermal growth factor receptor	Homo sapiens	135-139
28241428-4	2017	To validate quantitative performance, both recombinant S2,3PSA and benign-associated alpha2,6-linked sialyl N-glycan-carrying PSA (S2,6PSA) purified from culture supernatant of PSA cDNA transiently-transfected Chinese hamster ovary (CHO)-K1 cells were used as standard protein.	n-glycan	108-116	kallikrein related peptidase 3	Homo sapiens	126-129
28011641-6	2017	Here we report the structure of the lectin and EGF domains of L-selectin bound to a fucose mimetic; that is, a terminal mannose on an N-glycan attached to a symmetry-related molecule.	n-glycan	134-142	selectin L	Homo sapiens	62-72
28052004-11	2017	This study suggested that N-glycan variation of serum haptoglobin were associated with patients with gastric cancer and might be a promising marker for the cancer screening.	n-glycan	26-34	haptoglobin	Homo sapiens	54-65
28052004-1	2017	Based on our previous studies, differential analysis of N-glycan expression bound on serum haptoglobin reveals the quantitative variation on gastric cancer patients.	n-glycan	56-64	haptoglobin	Homo sapiens	91-102
27966990-5	2017	The objectives of the present study were to characterize N-glycosylation sites in VEGFR-2 via enzymatic release of the glycans and concomitant incorporation of 18O into formerly N-glycosylated sites followed by tandem mass spectrometry (MS/MS) analysis to determine N-glycosylation site occupancy and the site-specific N-glycan heterogeneity of VEGFR-2 glycopeptides.	n-glycan	319-327	kinase insert domain receptor	Homo sapiens	82-89
28170415-7	2017	rhLF, bLF and hLF had 23, 27 and 18 N-glycans respectively with 8 N-glycan in common overall.	n-glycan	36-44	HLF transcription factor, PAR bZIP family member	Homo sapiens	1-4
28170415-8	2017	rhLF shared 16 N-glycan with bLF and 9 N-glycan with hLF while bLF shared 10 N-glycan with hLF.	n-glycan	15-23	HLF transcription factor, PAR bZIP family member	Homo sapiens	1-4
28170415-8	2017	rhLF shared 16 N-glycan with bLF and 9 N-glycan with hLF while bLF shared 10 N-glycan with hLF.	n-glycan	39-47	HLF transcription factor, PAR bZIP family member	Homo sapiens	53-56
28170415-8	2017	rhLF shared 16 N-glycan with bLF and 9 N-glycan with hLF while bLF shared 10 N-glycan with hLF.	n-glycan	39-47	HLF transcription factor, PAR bZIP family member	Homo sapiens	53-56
27888538-0	2017	Specific N-glycan alterations are coupled in epithelial-mesenchymal transition induced by EGF in GE11 epithelial cells.	n-glycan	9-17	epidermal growth factor	Mus musculus	90-93
27888538-2	2017	The aim of this study was to evaluate specific N-glycan alterations during EMT induced by epidermal growth factor (EGF) in GE11 epithelial cells.	n-glycan	47-55	epidermal growth factor	Mus musculus	90-113
27888538-2	2017	The aim of this study was to evaluate specific N-glycan alterations during EMT induced by epidermal growth factor (EGF) in GE11 epithelial cells.	n-glycan	47-55	epidermal growth factor	Mus musculus	115-118
27888538-9	2017	Taken together, these results demonstrated that specific N-glycan alterations were coupled in EMT induced by EGF, which might be contributed to diagnosis and therapy of tumor metastasis.	n-glycan	57-65	epidermal growth factor	Mus musculus	109-112
30762989-5	2017	We previously identified PCa-associated aberrant glycosylation on PSA, that is, alpha2,3-linked sialylation as an additional terminal N-glycan on free PSA(S2,3PSA).	n-glycan	134-142	kallikrein related peptidase 3	Homo sapiens	66-69
30762989-5	2017	We previously identified PCa-associated aberrant glycosylation on PSA, that is, alpha2,3-linked sialylation as an additional terminal N-glycan on free PSA(S2,3PSA).	n-glycan	134-142	kallikrein related peptidase 3	Homo sapiens	151-154
27993676-6	2017	In addition, the apparent Km values of MmFUT8 and AtFucTA suggest that l-Fuc was preferentially transferred to N-glycan compared with l-Gal by fucosyltransferases.	n-glycan	111-119	fucosyltransferase 11	Arabidopsis thaliana	50-57
27550041-3	2016	Altogether, the N-glycan structures determined revealed that most of the N-glycans identified in donkey milk lactoferrin are neutral complex/hybrid.	n-glycan	16-24	lactotransferrin	Capra hircus	109-120
27993676-7	2017	Our results clearly demonstrate that MmFUT8 and AtFucTA transfer l-Gal residues from GDP-l-Gal and synthesize l-Gal containing N-glycan in vitro.	n-glycan	127-135	fucosyltransferase 11	Arabidopsis thaliana	48-55
27927990-2	2017	RFT1 was originally proposed to translocate the glycolipid Man5GlcNAc2-PP-dolichol (needed to synthesize N-glycan precursors) across the endoplasmic reticulum membrane, but subsequent studies showed that it does not play a direct role in transport.	n-glycan	105-113	glycolipid translocation protein	Saccharomyces cerevisiae S288C	0-4
27036738-13	2016	Our results suggest that MUC1 forms a lattice with the N-glycan of TRPV5 via galectin-3, which impairs TRPV5 endocytosis and increases urinary calcium reabsorption.	n-glycan	55-63	mucin 1, cell surface associated	Homo sapiens	25-29
27036738-13	2016	Our results suggest that MUC1 forms a lattice with the N-glycan of TRPV5 via galectin-3, which impairs TRPV5 endocytosis and increases urinary calcium reabsorption.	n-glycan	55-63	transient receptor potential cation channel subfamily V member 5	Homo sapiens	67-72
27036738-13	2016	Our results suggest that MUC1 forms a lattice with the N-glycan of TRPV5 via galectin-3, which impairs TRPV5 endocytosis and increases urinary calcium reabsorption.	n-glycan	55-63	galectin 3	Homo sapiens	77-87
27036738-13	2016	Our results suggest that MUC1 forms a lattice with the N-glycan of TRPV5 via galectin-3, which impairs TRPV5 endocytosis and increases urinary calcium reabsorption.	n-glycan	55-63	transient receptor potential cation channel subfamily V member 5	Homo sapiens	103-108
27492264-0	2016	The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc gamma receptor.	n-glycan	22-30	Fc gamma receptor Ia	Homo sapiens	80-97
27492264-3	2016	This interaction requires the presence of an asparagine-linked (N-)glycan on the Fc, and variations in the N-glycan composition can affect the affinity of CD16A binding (an FcgammaR).	n-glycan	107-115	Fc gamma receptor IIIa	Homo sapiens	155-160
27554083-8	2016	Indeed, loss of the N-glycan at N1515 resulted in markedly enhanced VWF clearance that was significantly faster than that observed with any previously described VWF mutations.	n-glycan	20-28	von Willebrand factor	Homo sapiens	68-71
27769287-7	2016	Moreover, RHO1 overexpression could also increase N-glycan site occupancy and the amount of secreted glycoproteins.	n-glycan	50-58	Rho family GTPase RHO1	Saccharomyces cerevisiae S288C	10-14
27554083-8	2016	Indeed, loss of the N-glycan at N1515 resulted in markedly enhanced VWF clearance that was significantly faster than that observed with any previously described VWF mutations.	n-glycan	20-28	von Willebrand factor	Homo sapiens	161-164
27517529-4	2016	Thiol end-modified HA was site-specifically conjugated to N-glycan on Fc region of oxidized DR5 Ab using a heterobifunctional linker of 3-(2-pyridyldithio)propionyl hydrazide (PDPH).	n-glycan	58-66	tumor necrosis factor receptor superfamily, member 10b	Mus musculus	92-95
27662763-1	2016	In this study, a ZIC-HILIC-MS methodology for the analysis of N-glycan isomers was optimized to obtain greater detection sensitivity and thus identify more glycan structures in hAGP.	n-glycan	62-70	Zic family member 1	Homo sapiens	17-20
27582506-5	2016	Here, we show that both of these sites can be modified with an N-glycan and that the glycan at position N747 modulates agonist-sensitivity of TRPA1 in vitro Additionally, we found that N-glycosylation also modulates cooperative effects of temperature and the agonist cinnamaldehyde on TRPA1 channel activation.	n-glycan	63-71	transient receptor potential cation channel subfamily A member 1	Homo sapiens	142-147
27547921-2	2016	To date, it has been unclear whether the N-glycan of GLUT4 contributes to its intracellular trafficking.	n-glycan	41-49	solute carrier family 2 member 4	Homo sapiens	53-58
27547921-3	2016	Here, to clarify the role of the N-glycan, we developed fluorogenic probes that label cytoplasmic and plasma-membrane proteins for multicolor imaging of GLUT4 translocation.	n-glycan	33-41	solute carrier family 2 member 4	Homo sapiens	153-158
27547921-5	2016	Using this probe, we verified the "log" of the trafficking, in which N-glycan-deficient GLUT4 was transiently translocated to the cell membrane upon insulin stimulation and was rapidly internalized without retention on the cell membrane.	n-glycan	69-77	solute carrier family 2 member 4	Homo sapiens	88-93
27547921-6	2016	The results strongly suggest that the N-glycan functions in the retention of GLUT4 on the cell membrane.	n-glycan	38-46	solute carrier family 2 member 4	Homo sapiens	77-82
27533464-0	2016	Comprehensive N-glycan profiles of hepatocellular carcinoma reveal association of fucosylation with tumor progression and regulation of FUT8 by microRNAs.	n-glycan	14-22	fucosyltransferase 8	Homo sapiens	136-140
27641064-8	2016	Moreover, the site-11 N-glycan exhibited a more branching structure compared with other sites, which may be required for EGFR-alpha5beta1 formation.	n-glycan	22-30	epidermal growth factor receptor	Bos taurus	121-125
27582638-8	2016	The separations of glycans in HILIC are sufficient to permit resolution of isomeric N-glycan structures, such as sialylated N-glycan isomers differing in alpha2-3 and alpha2-6 linkages, while these glycans remain attached to peptides.	n-glycan	84-92	immunoglobulin binding protein 1	Homo sapiens	167-175
26911286-3	2016	In contrast, late N-glycan maturation steps in the Golgi differ significantly in plants giving rise to complex N-glycans with beta1,2-linked xylose, core alpha1,3-linked fucose and Lewis A-type structures.	n-glycan	18-26	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	126-133
27582638-8	2016	The separations of glycans in HILIC are sufficient to permit resolution of isomeric N-glycan structures, such as sialylated N-glycan isomers differing in alpha2-3 and alpha2-6 linkages, while these glycans remain attached to peptides.	n-glycan	124-132	immunoglobulin binding protein 1	Homo sapiens	167-175
27457925-5	2016	In vitro, extracellular Gal-1 exerted divergent effects on eosinophils that were N-glycan- and dose-dependent.	n-glycan	81-89	lectin, galactose binding, soluble 1	Mus musculus	24-29
27314276-5	2016	A biantennary N-glycan (G0) and its analogous O-2 core xylosylated N-glycan (XG0) were synthesized, covalently conjugated to the model antigen ovalbumin, and analyzed for binding to a set of murine CLR-Fc fusion proteins using lectin microarray.	n-glycan	14-22	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	143-152
27137515-0	2016	N-Glycan profile analysis of transferrin using a microfluidic compact disc and MALDI-MS.	n-glycan	0-8	transferrin	Homo sapiens	29-40
27373711-5	2016	By combining the MSI approach with extract analysis, we were also able to assess which mass spectral peaks generated by MALDI-MSI could be assigned to unique N-glycan and peptide identities.	n-glycan	158-166	RB binding protein 4, chromatin remodeling factor	Homo sapiens	17-20
27373711-5	2016	By combining the MSI approach with extract analysis, we were also able to assess which mass spectral peaks generated by MALDI-MSI could be assigned to unique N-glycan and peptide identities.	n-glycan	158-166	RB binding protein 4, chromatin remodeling factor	Homo sapiens	126-129
26868756-1	2016	For the production of therapeutic proteins in plants, the presence of beta1,2-xylose and core alpha1,3-fucose on plants" N-glycan structures has been debated for their antigenic activity.	n-glycan	121-129	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	70-77
26868756-1	2016	For the production of therapeutic proteins in plants, the presence of beta1,2-xylose and core alpha1,3-fucose on plants" N-glycan structures has been debated for their antigenic activity.	n-glycan	121-129	adrenoceptor alpha 1D	Homo sapiens	94-102
27458028-5	2016	These functional studies show that leukocyte rolling on P- and L-selectin is ablated in cells lacking O-glycans, with N-glycan truncation also increasing cell rolling velocity on L-selectin.	n-glycan	118-126	selectin L	Homo sapiens	179-189
27098764-6	2016	We found that 5G2 recognized the Le(a) and Le(c) on N-glycan, and their major carrier proteins were CEACAM5 and CEACAM6.	n-glycan	52-60	C-C motif chemokine ligand 16	Homo sapiens	43-48
27314333-9	2016	Finally, we further showed that human Rspo1 is subjected to endoplasmic reticulum (ER) quality control in N-glycan-dependent manner.	n-glycan	106-114	R-spondin 1	Homo sapiens	38-43
27314333-10	2016	While N-glycan of Rspo1 plays a role in its intracellular stability, it had little effect on secreted Rspo1.	n-glycan	6-14	R-spondin 1	Homo sapiens	18-23
26733289-8	2016	We have noted significant dysregulation of two key N-glycan biosynthesis genes: ALG9 upregulated (P<0.001) and MGAT1 downregulated (P<0.01) in galactosaemia patients, which may contribute to its ongoing pathophysiology.	n-glycan	51-59	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	80-84
26733289-8	2016	We have noted significant dysregulation of two key N-glycan biosynthesis genes: ALG9 upregulated (P<0.001) and MGAT1 downregulated (P<0.01) in galactosaemia patients, which may contribute to its ongoing pathophysiology.	n-glycan	51-59	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	114-119
27294781-3	2016	This N-glycan-which is conserved in all SV2 isoforms across vertebrates-is essential for BoNT/A1 binding to neurons and for its potent neurotoxicity.	n-glycan	5-13	synaptic vesicle glycoprotein 2A	Homo sapiens	40-43
27302155-8	2016	Pregnancy associated changes of N-glycan bisection were different for IgA1 as compared to IgG-Fc described earlier.	n-glycan	32-40	immunoglobulin heavy constant alpha 1	Homo sapiens	70-74
26747426-2	2016	A complex-type-N-glycan bound at the extracellular residue Asn358 of TRPV5 through post-translational glycosylation has been postulated to regulate the activity of TRPV5 channels.	n-glycan	15-23	transient receptor potential cation channel, subfamily V, member 5	Mus musculus	69-74
26747426-2	2016	A complex-type-N-glycan bound at the extracellular residue Asn358 of TRPV5 through post-translational glycosylation has been postulated to regulate the activity of TRPV5 channels.	n-glycan	15-23	transient receptor potential cation channel, subfamily V, member 5	Mus musculus	164-169
26676362-0	2016	N-Glycan-based ER Molecular Chaperone and Protein Quality Control System: The Calnexin Binding Cycle.	n-glycan	0-8	calnexin	Homo sapiens	78-86
27015765-0	2016	Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan.	n-glycan	113-121	C-type lectin domain family 4 member A	Homo sapiens	27-61
27015765-2	2016	Here, we report the crystal structures of human DCIR C-type lectin domains in the absence and presence of a branched N-glycan unit.	n-glycan	117-125	C-type lectin domain family 4 member A	Homo sapiens	48-52
27057853-9	2016	The total N-glycan abundance levels were strongly positively correlated with levels of leptin and adiponectin in cord blood.	n-glycan	10-18	adiponectin, C1Q and collagen domain containing	Homo sapiens	98-109
26949374-5	2016	Endo- and exoglycosidases were used to investigate the different N-glycan patterns of LCN2.	n-glycan	65-73	lipocalin 2	Mus musculus	86-90
26972830-7	2016	The N-acetylglucosaminyltransferase enzymes of the N-glycan branching pathway (Mgat1,2,4,5) display multistep ultrasensitivity to UDP-GlcNAc, as well as branching-dependent compensation.	n-glycan	51-59	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	Mus musculus	4-35
26956484-8	2016	In human mast cells, inhibition of sialyl sulfation altered the N-glycan of Orai1 (and other proteins) and increased SOCE.	n-glycan	64-72	ORAI calcium release-activated calcium modulator 1	Homo sapiens	76-81
26949374-14	2016	CONCLUSIONS: These results suggest that the difference in the molecular weights of the LCN2 proteins was due to their N-glycan structure.	n-glycan	118-126	lipocalin 2	Mus musculus	87-91
26797772-5	2016	Using site-directed mutagenesis, we demonstrated that TNSALP has five N-glycans in transfected COS-1 cells and that individual single N-glycan deletion mutants of TNSALP retain the dimeric structure required for ALP activity, excluding the possibility that any single N-glycan plays a vital role in the structure and function of TNSALP.	n-glycan	70-78	alkaline phosphatase, biomineralization associated	Homo sapiens	54-60
26699903-0	2016	Electrostatics and N-glycan-mediated membrane tethering of SCUBE1 is critical for promoting bone morphogenetic protein signalling.	n-glycan	19-27	signal peptide, CUB domain, EGF-like 1	Danio rerio	59-65
26699903-0	2016	Electrostatics and N-glycan-mediated membrane tethering of SCUBE1 is critical for promoting bone morphogenetic protein signalling.	n-glycan	19-27	bone morphogenetic protein 1	Homo sapiens	92-118
26797772-5	2016	Using site-directed mutagenesis, we demonstrated that TNSALP has five N-glycans in transfected COS-1 cells and that individual single N-glycan deletion mutants of TNSALP retain the dimeric structure required for ALP activity, excluding the possibility that any single N-glycan plays a vital role in the structure and function of TNSALP.	n-glycan	70-78	ATHS	Homo sapiens	57-60
26797772-5	2016	Using site-directed mutagenesis, we demonstrated that TNSALP has five N-glycans in transfected COS-1 cells and that individual single N-glycan deletion mutants of TNSALP retain the dimeric structure required for ALP activity, excluding the possibility that any single N-glycan plays a vital role in the structure and function of TNSALP.	n-glycan	134-142	alkaline phosphatase, biomineralization associated	Homo sapiens	163-169
26797772-5	2016	Using site-directed mutagenesis, we demonstrated that TNSALP has five N-glycans in transfected COS-1 cells and that individual single N-glycan deletion mutants of TNSALP retain the dimeric structure required for ALP activity, excluding the possibility that any single N-glycan plays a vital role in the structure and function of TNSALP.	n-glycan	134-142	alkaline phosphatase, biomineralization associated	Homo sapiens	163-169
26797772-9	2016	A comprehensive analysis of a series of multiple N-glycan depletion mutants in TNSALP revealed that three N-glycans on N230, N271 and N303 were the minimal requirement for the structure and function of TNSALP and a prerequisite for its stable expression in a cell.	n-glycan	49-57	alkaline phosphatase, biomineralization associated	Homo sapiens	79-85
26797772-9	2016	A comprehensive analysis of a series of multiple N-glycan depletion mutants in TNSALP revealed that three N-glycans on N230, N271 and N303 were the minimal requirement for the structure and function of TNSALP and a prerequisite for its stable expression in a cell.	n-glycan	49-57	alkaline phosphatase, biomineralization associated	Homo sapiens	202-208
26537754-13	2016	These data highlight the important role of the N-glycan Asn(575) and the C-terminal disulfide loop of rBAT in biogenesis of the rBAT-b(0,+)AT heterodimer.	n-glycan	47-55	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	128-132
26721884-12	2016	In contrast, mutations of NKCC2 N-glycosylation sites abolished the effects of OS9, indicating that OS9-induced protein degradation is N-glycan-dependent.	n-glycan	135-143	solute carrier family 12 member 1	Homo sapiens	26-31
26721884-12	2016	In contrast, mutations of NKCC2 N-glycosylation sites abolished the effects of OS9, indicating that OS9-induced protein degradation is N-glycan-dependent.	n-glycan	135-143	OS9 endoplasmic reticulum lectin	Homo sapiens	79-82
26721884-12	2016	In contrast, mutations of NKCC2 N-glycosylation sites abolished the effects of OS9, indicating that OS9-induced protein degradation is N-glycan-dependent.	n-glycan	135-143	OS9 endoplasmic reticulum lectin	Homo sapiens	100-103
26537754-13	2016	These data highlight the important role of the N-glycan Asn(575) and the C-terminal disulfide loop of rBAT in biogenesis of the rBAT-b(0,+)AT heterodimer.	n-glycan	47-55	solute carrier family 7 member 9	Homo sapiens	133-141
26059044-0	2016	The N-glycan on Asn54 affects the atypical N-glycan composition of plant-produced interleukin-22, but does not influence its activity.	n-glycan	4-12	interleukin 22	Homo sapiens	82-96
26503547-0	2016	Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner .	n-glycan	127-135	trophoblast glycoprotein	Homo sapiens	31-36
26059044-0	2016	The N-glycan on Asn54 affects the atypical N-glycan composition of plant-produced interleukin-22, but does not influence its activity.	n-glycan	43-51	interleukin 22	Homo sapiens	82-96
26059044-9	2016	However, we do show that the presence of a N-glycan on Asn54 contributes to the atypical N-glycan composition of plant-produced IL-22 and influences the N-glycan composition of N-glycans on other positions.	n-glycan	43-51	interleukin 22	Homo sapiens	128-133
26829325-9	2016	Utilising peptide N-glycosidase-F and neuraminidase to remove N-glycans and sialic acids, respectively, we found that N-glycan composition (but not sialylation alone) were responsible for this reduction in molecular weight.	n-glycan	62-70	neuraminidase 1	Homo sapiens	38-51
26059044-9	2016	However, we do show that the presence of a N-glycan on Asn54 contributes to the atypical N-glycan composition of plant-produced IL-22 and influences the N-glycan composition of N-glycans on other positions.	n-glycan	89-97	interleukin 22	Homo sapiens	128-133
26059044-9	2016	However, we do show that the presence of a N-glycan on Asn54 contributes to the atypical N-glycan composition of plant-produced IL-22 and influences the N-glycan composition of N-glycans on other positions.	n-glycan	89-97	interleukin 22	Homo sapiens	128-133
27855403-3	2016	Previously, we have systematically identified the glycoproteins that interact with FBXO6 in an N-glycan dependent manner by LC/MS spectrum and confirmed the interaction between FBXO6 and glycosylated Ero1L, a protein disulfide oxidase in endoplasmic reticulum (ER).	n-glycan	95-103	F-box protein 6	Homo sapiens	83-88
27855403-3	2016	Previously, we have systematically identified the glycoproteins that interact with FBXO6 in an N-glycan dependent manner by LC/MS spectrum and confirmed the interaction between FBXO6 and glycosylated Ero1L, a protein disulfide oxidase in endoplasmic reticulum (ER).	n-glycan	95-103	endoplasmic reticulum oxidoreductase 1 alpha	Homo sapiens	200-205
26452604-0	2015	The role of N-glycan modification of TNFR1 in inflammatory microglia activation.	n-glycan	12-20	TNF receptor superfamily member 1A	Homo sapiens	37-42
26680341-2	2015	Given the importance of protein glycosylation for immune function, we investigated the effect that modulation of the highly conserved HLA class I N-glycan has on KIR:HLA interactions and NK cell function.	n-glycan	146-154	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	Homo sapiens	162-165
26680341-5	2015	In addition, the functional outcomes of HLA-B*57:01 N-glycan disruption/modulation on KIR3DL1zeta+ Jurkat reporter cells and primary human KIR3DL1+ NK cells was assessed.	n-glycan	52-60	killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1	Homo sapiens	86-93
26240167-3	2015	We applied newly developed mass spectrometry-based analytics to quantify site-specific N-glycan remodeling of the model protein Pdi1p expressed in insect cells.	n-glycan	87-95	peptidyl arginine deiminase 1	Homo sapiens	128-133
26567221-4	2016	We found two consensus (N37 and N134) and one non-consensus (N135) residues that were N-glycosylated in HMGB1 by performing liquid chromatography tandem mass spectrometry (LC-MS/MS) and analyzing for N-glycan composition and structure.	n-glycan	200-208	high mobility group box 1	Homo sapiens	104-109
26440530-0	2016	A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA.	n-glycan	79-87	erb-b2 receptor tyrosine kinase 2	Homo sapiens	21-25
26440530-0	2016	A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA.	n-glycan	79-87	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	26-29
26440530-0	2016	A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA.	n-glycan	79-87	immunoglobulin heavy constant gamma 1 (G1m marker)	Mus musculus	34-38
26440530-0	2016	A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA.	n-glycan	79-87	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	107-110
26440530-5	2016	The polymerization propensity of anti-HER2 IgA2m2 could be suppressed by an 18-aa deletion of the heavy chain tailpiece - coinciding with the loss of high-mannose type N-glycan species - as well as by 2 cysteine to serine mutations at positions 320 and 480.	n-glycan	168-176	erb-b2 receptor tyrosine kinase 2	Homo sapiens	38-42
26296369-5	2015	In agreement, the glycomics analysis determines the glycosylation site and the N-glycan composition of CD69, and terminal removal of sialic acid from that N-linked glycans reverses the generation of forkhead box P3-positive Treg cells (23.21%; P < 0.05).	n-glycan	79-87	CD69 molecule	Homo sapiens	103-107
26154505-0	2015	Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N-glycan branching and sialylation.	n-glycan	76-84	erythropoietin	Cricetulus griseus	61-75
26448449-0	2015	Mass Spectrometric N-Glycan Analysis of Haptoglobin from Patient Serum Samples Using a 96-Well Plate Format.	n-glycan	19-27	haptoglobin	Homo sapiens	40-51
26109616-0	2015	Altered beta1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin beta1 are associated with early spontaneous miscarriage in humans.	n-glycan	53-61	integrin subunit beta 1	Homo sapiens	65-79
26335373-6	2015	Application of the strategy to chicken ovalbumin, normal mouse mammary epithelial cells (NMuMG), and human serum resulted in detection of 5, 6, and 11 additional N-glycan structures, respectively.	n-glycan	162-170	ovalbumin (SERPINB14)	Gallus gallus	39-48
26496683-4	2015	Here, we employ chemical biology methods for UPR regulation to show that stress-independent activation of the UPR"s XBP1s transcription factor also induces a panel of N-glycan maturation-related enzymes.	n-glycan	167-175	X-box binding protein 1	Homo sapiens	116-120
26241388-1	2015	Fused lobes (FDL) is an enzyme that simultaneously catalyzes a key trimming reaction and antagonizes elongation reactions in the insect N-glycan processing pathway.	n-glycan	136-144	fused lobes	Drosophila melanogaster	13-16
26241388-6	2015	Our results also confirm the key role of FDL at the major branch point distinguishing insect and mammalian N-glycan processing pathways.	n-glycan	107-115	fused lobes	Drosophila melanogaster	41-44
26085185-11	2015	EGFR-specific N-glycan signatures included high bisecting beta1,4-GlcNAcylation and low alpha2,3-sialylation (both P < 0.05) relative to EGFR-negative CRC tissues.	n-glycan	14-22	epidermal growth factor receptor	Homo sapiens	0-4
26085185-12	2015	This is the first study to correlate CRC stage and EGFR status with specific N-glycan features, thus advancing our understanding of the mechanisms causing the biomolecular deregulation associated with CRC.	n-glycan	77-85	epidermal growth factor receptor	Homo sapiens	51-55
26206179-5	2015	The results of a glycomic analysis reported herein demonstrate the presence of a core-fucose in an N-glycan on enriched SP-D from pooled human sera.	n-glycan	99-107	surfactant protein D	Homo sapiens	120-124
26206179-12	2015	We performed an N-glycomic analysis of human serum SP-D and the results show that a core-fucose is present in its N-glycan.	n-glycan	114-122	surfactant protein D	Homo sapiens	51-55
26244810-0	2015	Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice.	n-glycan	30-38	fucosyltransferase 4	Mus musculus	62-69
26244810-0	2015	Large-Scale Identification of N-Glycan Glycoproteins Carrying Lewis x and Site-Specific N-Glycan Alterations in Fut9 Knockout Mice.	n-glycan	30-38	fucosyltransferase 9	Mus musculus	112-116
26244810-8	2015	Our analyses demonstrated that 24/32 glycoproteins contained the Le(x) N-glycan structure in wild-type kidney; of these, Le(x) was lost from 21 in the knockout mice.	n-glycan	71-79	fucosyltransferase 4	Mus musculus	65-70
26478188-0	2015	A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner.	n-glycan	125-133	angiopoietin 1	Homo sapiens	11-25
26478188-0	2015	A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner.	n-glycan	125-133	matrilin 1	Homo sapiens	43-46
26478188-0	2015	A Designed Angiopoietin-1 Variant, Dimeric CMP-Ang1 Activates Tie2 and Stimulates Angiogenesis and Vascular Stabilization in N-glycan Dependent Manner.	n-glycan	125-133	angiopoietin 1	Homo sapiens	47-51
26478188-8	2015	Taken together, our results indicate that dimeric CMP-Ang1 is capable of activating Tie2 and stimulating angiogenesis in N-glycan dependent manner.	n-glycan	121-129	matrilin 1	Homo sapiens	50-53
26478188-8	2015	Taken together, our results indicate that dimeric CMP-Ang1 is capable of activating Tie2 and stimulating angiogenesis in N-glycan dependent manner.	n-glycan	121-129	angiopoietin 1	Homo sapiens	54-58
26224316-4	2015	We show that human JAM-A contains a single N-glycan at N185 and that this residue is conserved across multiple mammalian species.	n-glycan	43-51	F11 receptor	Homo sapiens	19-24
25541284-0	2015	The role of N-glycan in folding, trafficking and pathogenicity of myelin oligodendrocyte glycoprotein (MOG).	n-glycan	12-20	myelin oligodendrocyte glycoprotein	Homo sapiens	66-101
25541284-0	2015	The role of N-glycan in folding, trafficking and pathogenicity of myelin oligodendrocyte glycoprotein (MOG).	n-glycan	12-20	myelin oligodendrocyte glycoprotein	Homo sapiens	103-106
26109616-16	2015	beta1,6-GlcNAc N-glycan was mainly located outside of the STB and CTB layer in normal villi and was expressed only rarely in the ESM villi.	n-glycan	15-23	chitobiase	Homo sapiens	66-69
25787342-5	2015	A statistically significant correlation between N-glycan profiles of bloodstains and chronological age was found and a statistical model that can be used for the age prediction was designed (Age = 75.59 - 5.15 x (GP4)(2)+ 17.07 x GP6 - 5.30 x (GP10)(2) - 16.56 x GP16 + 20.07 x GP20 - 7.54 x (GP20)(2) + 16.47 x GP22).	n-glycan	48-56	CD36 molecule	Homo sapiens	213-216
25787342-5	2015	A statistically significant correlation between N-glycan profiles of bloodstains and chronological age was found and a statistical model that can be used for the age prediction was designed (Age = 75.59 - 5.15 x (GP4)(2)+ 17.07 x GP6 - 5.30 x (GP10)(2) - 16.56 x GP16 + 20.07 x GP20 - 7.54 x (GP20)(2) + 16.47 x GP22).	n-glycan	48-56	glycoprotein VI platelet	Homo sapiens	230-233
26271046-6	2015	In the present study, using a series of mutants lacking potential N-glycosylation sites (N256, N370, N406, and N413) within GluA2, we demonstrated that the mutant lacking the N-glycan at N370 strongly suppressed the intracellular trafficking of GluA2 from the endoplasmic reticulum (ER) in HEK293 cells.	n-glycan	175-183	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	124-129
26291458-13	2015	As such, we postulate a profound shift in N-glycan function from affecting Smo ER exit in flies to influencing its signal output in mice.	n-glycan	42-50	smoothened, frizzled class receptor	Mus musculus	75-78
26271046-6	2015	In the present study, using a series of mutants lacking potential N-glycosylation sites (N256, N370, N406, and N413) within GluA2, we demonstrated that the mutant lacking the N-glycan at N370 strongly suppressed the intracellular trafficking of GluA2 from the endoplasmic reticulum (ER) in HEK293 cells.	n-glycan	175-183	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	245-250
26271046-10	2015	The HNK-1 epitope on N-glycan at the N413 of GluA2 was also involved in the cell surface expression of GluA1.	n-glycan	21-29	beta-1,3-glucuronyltransferase 1	Homo sapiens	4-9
26271046-10	2015	The HNK-1 epitope on N-glycan at the N413 of GluA2 was also involved in the cell surface expression of GluA1.	n-glycan	21-29	glutamate ionotropic receptor AMPA type subunit 2	Homo sapiens	45-50
26271046-10	2015	The HNK-1 epitope on N-glycan at the N413 of GluA2 was also involved in the cell surface expression of GluA1.	n-glycan	21-29	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	103-108
26001781-0	2015	Limited Addition of the 6-Arm beta1,2-linked N-Acetylglucosamine (GlcNAc) Residue Facilitates the Formation of the Largest N-Glycan in Plants.	n-glycan	123-131	beta-1,2-xylosyltransferase	Arabidopsis thaliana	30-37
25998389-7	2015	Finally, the N-glycan released from the EPO transfected with ST3GAL4 siRNA showed a prominent reduction in sialyation level among the single siRNA transfections.	n-glycan	13-21	erythropoietin	Cricetulus griseus	40-43
25998389-7	2015	Finally, the N-glycan released from the EPO transfected with ST3GAL4 siRNA showed a prominent reduction in sialyation level among the single siRNA transfections.	n-glycan	13-21	CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4	Cricetulus griseus	61-68
26001781-4	2015	Furthermore, analysis of gnt2 mutant and 35S:GnTII transgenic plants shows that the addition of the 6-arm non-reducing GlcNAc residue to the common N-glycan acceptor GlcNAcMan3(GlcNAc)2 inhibits additions of the core beta1,2-xylose and alpha1,3-fucose residues.	n-glycan	148-156	beta-1,2-xylosyltransferase	Arabidopsis thaliana	217-224
28717478-1	2015	The combination of solid phase peptide synthesis and endo-beta-N-acetylglucosaminidase (ENGase) catalysed glycosylation is a powerful convergent synthetic method allowing access to glycopeptides bearing full-length N-glycan structures.	n-glycan	215-223	O-GlcNAcase	Homo sapiens	58-86
28717478-1	2015	The combination of solid phase peptide synthesis and endo-beta-N-acetylglucosaminidase (ENGase) catalysed glycosylation is a powerful convergent synthetic method allowing access to glycopeptides bearing full-length N-glycan structures.	n-glycan	215-223	endo-beta-N-acetylglucosaminidase	Homo sapiens	88-94
26222427-9	2015	These results show that the Ts4-epitope contains agalacto-biantennary N-glycan with bisecting GlcNAc carrying fucose residues.	n-glycan	70-78	Trichinella spiralis resistance 4	Mus musculus	28-31
26171609-0	2015	N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin.	n-glycan	0-8	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	91-96
26171609-0	2015	N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin.	n-glycan	0-8	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	97-114
26171609-3	2015	The N-glycan on 25-kDa HAI-2 appears to be of the oligomannose type and that on 30-40-kDa HAI-2 to be of complex type with extensive terminal N-acetylglucosamine branching.	n-glycan	4-12	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	23-28
26171609-4	2015	The two different types of N-glycan differentially mask two epitopes on HAI-2 polypeptide, recognized by two different HAI-2 mAbs.	n-glycan	27-35	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	72-77
26171609-4	2015	The two different types of N-glycan differentially mask two epitopes on HAI-2 polypeptide, recognized by two different HAI-2 mAbs.	n-glycan	27-35	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	119-124
26171609-11	2015	Our study reveals that N-glycan branching regulates HAI-2 through different subcellular distribution and subsequently access to different target proteases.	n-glycan	23-31	serine peptidase inhibitor, Kunitz type 2	Homo sapiens	52-57
26023238-0	2015	Pancreatic alpha-Amylase Controls Glucose Assimilation by Duodenal Retrieval through N-Glycan-specific Binding, Endocytosis, and Degradation.	n-glycan	85-93	amylase alpha 2A	Homo sapiens	0-24
26023238-9	2015	We demonstrated that after N-glycan binding, pancreatic alpha-amylase underwent internalization into lysosomes in a process that was inhibited by alpha-mannoside.	n-glycan	27-35	amylase alpha 2A	Homo sapiens	45-69
26023238-12	2015	Our findings indicate that N-glycan recognition by alpha-amylase protects enterocytes against a sudden increase in glucose concentration and restores glucose uptake by gradual internalization, which homeostatically controls the postprandial blood glucose level.	n-glycan	27-35	LOW QUALITY PROTEIN: pancreatic alpha-amylase	Sus scrofa	51-64
26001781-1	2015	The most abundant N-glycan in plants is the paucimannosidic N-glycan with core beta1,2-xylose and alpha1,3-fucose residues (Man3XylFuc(GlcNAc)2).	n-glycan	18-26	beta-1,2-xylosyltransferase	Arabidopsis thaliana	79-86
26001781-1	2015	The most abundant N-glycan in plants is the paucimannosidic N-glycan with core beta1,2-xylose and alpha1,3-fucose residues (Man3XylFuc(GlcNAc)2).	n-glycan	60-68	beta-1,2-xylosyltransferase	Arabidopsis thaliana	79-86
25797607-4	2015	D197, which results in loss of an N-glycan located near the HIV Env trimer apex, was detected in brain in some HAD patients, while position 200 was estimated to be under positive selection.	n-glycan	34-42	endogenous retrovirus group K member 20	Homo sapiens	64-67
25921843-9	2015	Compared to baseline, metformin significantly improved metabolic parameters and insulin sensitivity, increased SIRT1 gene/protein expression and SIRT1 promoter chromatin accessibility, elevated mTOR gene expression with concomitant reduction in p70S6K phosphorylation in subjects" PBMCs, and modified the plasma N-glycan profile.	n-glycan	312-320	ribosomal protein S6 kinase B1	Homo sapiens	245-251
25416425-7	2015	The decrease in surface protein level of Kv1.4 was mainly due to a reduction in total protein level, induced by altered N-glycan composition.	n-glycan	120-128	potassium voltage-gated channel subfamily A member 4	Homo sapiens	41-46
26121645-10	2015	It was shown that the N-glycan environment around well-defined disulphide bridges of gp120 is highly critical to allow efficient viral infection and transmission.	n-glycan	22-30	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	85-90
25855029-3	2015	We recently reported that the N-glycan profile of clusterin is altered in the plasma of ccRCC patients.	n-glycan	30-38	clusterin	Homo sapiens	50-59
25645918-4	2015	The timely expressed human azurophilic granule-resident beta-hexosaminidase A displayed the capacity to generate paucimannosidic N-glycans by trimming hybrid/complex type N-glycan intermediates with relative broad substrate specificity.	n-glycan	129-137	O-GlcNAcase	Homo sapiens	56-75
25416425-2	2015	Kv1.4 N354Q, without an N-glycan, exhibited decreased protein stability and trafficking to the cell surface (Watanabe et al.	n-glycan	24-32	potassium voltage-gated channel subfamily A member 4	Homo sapiens	0-5
25499076-6	2015	The main objective of this study was to determine the N-glycan structures present in native, pituitary G-hPRL and compare them with those present in the recombinant hormone.	n-glycan	54-62	prolactin	Homo sapiens	105-109
25499076-11	2015	N-Glycan profiling proved to be a useful and accurate methodology also for MM and carbohydrate content determination for the two G-hPRL preparations, in good agreement with the values obtained directly via MALDI-TOF-MS.	n-glycan	0-8	prolactin	Homo sapiens	131-135
25475176-4	2015	An N-glycan precursor with Man5GlcNAc2 is necessary but not sufficient for N-glycan QC, which is predicted by the presence of the UDP-glucose:glucosyltransferase (UGGT) plus calreticulin and/or calnexin.	n-glycan	3-11	calreticulin	Homo sapiens	174-186
25475176-4	2015	An N-glycan precursor with Man5GlcNAc2 is necessary but not sufficient for N-glycan QC, which is predicted by the presence of the UDP-glucose:glucosyltransferase (UGGT) plus calreticulin and/or calnexin.	n-glycan	3-11	calnexin	Homo sapiens	194-202
25475176-6	2015	The presence of an armless calnexin in Toxoplasma suggests secondary loss of N-glycan QC from coccidia.	n-glycan	77-85	calnexin	Homo sapiens	27-35
25416425-8	2015	Kv1.4 in CSTP-treated cells carried a unique oligomannose-type N-glycan that contains three glucose residues.	n-glycan	63-71	potassium voltage-gated channel subfamily A member 4	Homo sapiens	0-5
25416425-9	2015	This N-glycan had the most negative effect on cell surface expression of Kv1.4.	n-glycan	5-13	potassium voltage-gated channel subfamily A member 4	Homo sapiens	73-78
25416425-11	2015	Our data suggest that composition of the N-glycan plays an important role in protein stability and trafficking, and a sialylated complex-type N-glycan promoted high cell surface expression of Kv1.4.	n-glycan	142-150	potassium voltage-gated channel subfamily A member 4	Homo sapiens	192-197
26045989-0	2015	Upregulated beta1-6 branch N-glycan marks early gliomagenesis but exhibited biphasic expression in the progression of astrocytic glioma.	n-glycan	27-35	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	12-19
25595436-9	2015	N-glycan sequencing of CP confirmed the increase of sLe(x) levels in CP in PDAC patients.	n-glycan	0-8	ceruloplasmin	Homo sapiens	23-25
25595436-9	2015	N-glycan sequencing of CP confirmed the increase of sLe(x) levels in CP in PDAC patients.	n-glycan	0-8	ceruloplasmin	Homo sapiens	69-71
25395405-6	2015	Tetracycline (tet)-induced overexpression of Mgat1, Mgat5 and Mgat6 resulted in increased enzyme activity and increased N-glycan branching concordant with the known specificities of these enzymes.	n-glycan	120-128	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	45-50
25705140-5	2015	The method is applied to a branched N-glycan found on the HIV gp120 protein, and a linear N-glycan.	n-glycan	36-44	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	62-67
25395405-6	2015	Tetracycline (tet)-induced overexpression of Mgat1, Mgat5 and Mgat6 resulted in increased enzyme activity and increased N-glycan branching concordant with the known specificities of these enzymes.	n-glycan	120-128	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	52-57
25193875-7	2015	These results suggest that inhibition of BmFDL and BmGlcNAcase2 could increase GlcNAc-type N-glycan levels.	n-glycan	91-99	fused lobes	Bombyx mori	41-46
25193875-7	2015	These results suggest that inhibition of BmFDL and BmGlcNAcase2 could increase GlcNAc-type N-glycan levels.	n-glycan	91-99	beta-N-acetylglucosaminidase 2	Bombyx mori	51-63
25487964-1	2015	Glycoside hydrolase family 99 (GH99) was created to categorize sequence-related glycosidases possessing endo-alpha-mannosidase activity: the cleavage of mannosidic linkages within eukaryotic N-glycan precursors (Glc1-3 Man9 GlcNAc2 ), releasing mono-, di- and triglucosylated-mannose (Glc1-3 -1,3-Man).	n-glycan	191-199	mannosidase endo-alpha	Homo sapiens	104-126
25551295-8	2015	Two-dimensional heteronuclear single-quantum coherence spectra of the Gnt1 product, containing a single [(13)C,(15)N]GlcNAc residue on each N-glycan, showed that the N-glycan is stabilized through interactions with polypeptide residues.	n-glycan	140-148	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	70-74
25551295-8	2015	Two-dimensional heteronuclear single-quantum coherence spectra of the Gnt1 product, containing a single [(13)C,(15)N]GlcNAc residue on each N-glycan, showed that the N-glycan is stabilized through interactions with polypeptide residues.	n-glycan	166-174	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	70-74
25551295-11	2015	Gnt1 and Gnt2 catalyze fundamental reactions in the synthesis of every glycoprotein with a complex-type N-glycan; thus, the strategies presented herein can be applied to a broad range of glycoprotein studies.	n-glycan	104-112	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-4
25551295-11	2015	Gnt1 and Gnt2 catalyze fundamental reactions in the synthesis of every glycoprotein with a complex-type N-glycan; thus, the strategies presented herein can be applied to a broad range of glycoprotein studies.	n-glycan	104-112	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	9-13
26235586-10	2015	In addition, peptide-N-glycosidase F treatment of CMAH indicated that secretory CMAH was a glycoprotein with N-glycan.	n-glycan	109-117	cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene	Homo sapiens	50-54
25462875-7	2015	The results demonstrated a correlation between the levels of intracellular B4GALT1 activity and terminally galactosylated N-glycans, N-glycan branching, the appearance of hybrid structures, and reduced core fucosylation.	n-glycan	122-130	beta-1,4-galactosyltransferase 1	Homo sapiens	75-82
25462875-8	2015	Thus, engineering B4GALT1 to reduce its cleavage and secretion is an approach that can be used to enhance N-glycan elongation in insect cells.	n-glycan	106-114	beta-1,4-galactosyltransferase 1	Homo sapiens	18-25
26235586-10	2015	In addition, peptide-N-glycosidase F treatment of CMAH indicated that secretory CMAH was a glycoprotein with N-glycan.	n-glycan	109-117	cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene	Homo sapiens	80-84
26261057-8	2015	The mass spectra of the N-glycosylated peptide revealed that the observed biological properties were attributable to the characteristic N-glycan structures of the anti-CD20 mAbs produced in the transgenic silkworms, i.e., the lack of the core-fucose and galactose at the non-reducing terminal.	n-glycan	136-144	keratin 20	Homo sapiens	168-172
25692844-7	2015	The lectin exhibits specificity towards GlcNAc, but also reacts with N-glycan structures.	n-glycan	69-77	F-box protein PP2-B11-like	Nicotiana tabacum	4-10
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	n-glycan	81-89	carboxypeptidase A4	Homo sapiens	39-43
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	n-glycan	81-89	serpin family A member 1	Homo sapiens	45-48
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	n-glycan	81-89	haptoglobin	Homo sapiens	50-52
26167486-6	2015	Further analysis by lectin showed that CPA4, AAT, HP, and HSC70 were secreted as N-glycan in the medium of MCF-7, with HP also showing differentially N-glycosylated isoforms.	n-glycan	81-89	heat shock protein family A (Hsp70) member 8	Homo sapiens	58-63
26167486-7	2015	For the HMEpC, only CPA4 was detected as N-glycan.	n-glycan	41-49	carboxypeptidase A4	Homo sapiens	20-24
25139750-2	2015	Conformational dynamics of malectin"s exquisite selectivity for diglucosylated N-glycan (Dig-N-glycan), a highly flexible oligosaccharide comprising of numerous dihedral torsion angles, are described as an example.	n-glycan	79-87	malectin	Homo sapiens	27-35
25479762-6	2014	Herein, we investigated a new antibody-lectin sandwich array (ALSA) platform to determine whether this microanalytical technique could be applied to the characterization of N-glycan content of hGGT1 in complex biological samples.	n-glycan	173-181	gamma-glutamyltransferase 1	Homo sapiens	193-198
26039485-0	2015	Arabidopsis thaliana KORRIGAN1 protein: N-glycan modification, localization, and function in cellulose biosynthesis and osmotic stress responses.	n-glycan	40-48	glycosyl hydrolase 9A1	Arabidopsis thaliana	21-30
25378396-3	2014	Secreted Klotho (sKL) up-regulates the TRPV5 calcium channel from the cell exterior by removing sialic acids from N-glycan of the channel and inhibiting its endocytosis.	n-glycan	114-122	klotho	Homo sapiens	9-15
25378396-3	2014	Secreted Klotho (sKL) up-regulates the TRPV5 calcium channel from the cell exterior by removing sialic acids from N-glycan of the channel and inhibiting its endocytosis.	n-glycan	114-122	transient receptor potential cation channel subfamily V member 5	Homo sapiens	39-44
25479762-10	2014	The lectin binding patterns obtained with the ALSA platform are consistent with the hGGT1 N-glycan composition obtained from previous large-scale hGGT1 N-glycan characterizations from these sources.	n-glycan	90-98	gamma-glutamyltransferase 1	Homo sapiens	84-89
25479762-10	2014	The lectin binding patterns obtained with the ALSA platform are consistent with the hGGT1 N-glycan composition obtained from previous large-scale hGGT1 N-glycan characterizations from these sources.	n-glycan	152-160	gamma-glutamyltransferase 1	Homo sapiens	84-89
25365149-4	2014	The reported mutations in PGM3 led to an impaired biosynthesis of UDP-GlcNAc and impaired tri-antennary and tetra-antennary N-glycan structures.	n-glycan	124-132	phosphoglucomutase 3	Homo sapiens	26-30
25474158-13	2014	The fourth TLR2 N-glycan was especially critical for the rPCN-TLR2 interaction.	n-glycan	16-24	toll like receptor 2	Homo sapiens	11-15
25474158-13	2014	The fourth TLR2 N-glycan was especially critical for the rPCN-TLR2 interaction.	n-glycan	16-24	plectin	Rattus norvegicus	57-61
25474158-13	2014	The fourth TLR2 N-glycan was especially critical for the rPCN-TLR2 interaction.	n-glycan	16-24	toll like receptor 2	Homo sapiens	62-66
25355867-0	2014	Proteolytic and N-glycan processing of human alpha1-antitrypsin expressed in Nicotiana benthamiana.	n-glycan	16-24	serpin family A member 1	Homo sapiens	45-63
25271059-7	2014	We identified a mechanism in which galactosyltransferase 4 isoform regulated N-glycan branching on the nascent protein, subsequently controlling biological activity in an in vivo model of hCG activity.	n-glycan	77-85	hypertrichosis 2 (generalised, congenital)	Homo sapiens	188-191
25230686-5	2014	Using co-localization analysis and N-glycan profiling, we show that the transmembrane domain of GnTI is the major determinant for its cis/medial-Golgi localization.	n-glycan	35-43	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	96-100
25230686-8	2014	Our results suggest that sequence-specific features in the transmembrane domain of GnTI account for its steady-state distribution in the cis/medial-Golgi in plants, which is a prerequisite for efficient N-glycan processing in vivo.	n-glycan	203-211	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	83-87
25470275-3	2014	We examined the profiles of N-glycan and glycogene expression in transforming growth factor-beta (TGFbeta)-induced EMT using non-malignant bladder transitional epithelium HCV29 cells.	n-glycan	28-36	transforming growth factor beta 1	Homo sapiens	65-96
25470275-3	2014	We examined the profiles of N-glycan and glycogene expression in transforming growth factor-beta (TGFbeta)-induced EMT using non-malignant bladder transitional epithelium HCV29 cells.	n-glycan	28-36	transforming growth factor beta 1	Homo sapiens	98-105
25470275-5	2014	The expression of 5 N-glycan-related genes were notably altered in TGFbeta-induced EMT.	n-glycan	20-28	transforming growth factor beta 1	Homo sapiens	67-74
25355867-8	2014	Notwithstanding, an intensive glycoengineering approach led to secreted A1AT carrying sialylated N-glycan structures largely resembling its serum-derived counterpart.	n-glycan	97-105	serpin family A member 1	Homo sapiens	72-76
25299151-7	2014	The LC method is capable of separating sialylated N-glycan isomers differing in alpha2-3 and alpha2-6 linkages using a novel superficially porous particle (Fused-Core) Penta-HILIC (hydrophilic interaction liquid chromatography) column.	n-glycan	50-58	immunoglobulin binding protein 1	Homo sapiens	93-101
25305020-3	2014	In the present study, we purified the glycosylated extracellular domain of calcium-sensing receptor (CaSR) (ECD) (residues 20-612), containing either complex or high mannose N-glycan structures depending on the host cell line employed for recombinant expression.	n-glycan	174-182	calcium sensing receptor	Homo sapiens	75-99
25305020-3	2014	In the present study, we purified the glycosylated extracellular domain of calcium-sensing receptor (CaSR) (ECD) (residues 20-612), containing either complex or high mannose N-glycan structures depending on the host cell line employed for recombinant expression.	n-glycan	174-182	calcium sensing receptor	Homo sapiens	101-105
25451255-0	2014	The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin beta1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway.	n-glycan	11-19	erb-b2 receptor tyrosine kinase 3	Homo sapiens	47-52
25451255-0	2014	The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin beta1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway.	n-glycan	11-19	hypoxia inducible factor 1 subunit alpha	Homo sapiens	133-138
25451255-0	2014	The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin beta1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway.	n-glycan	11-19	NFE2 like bZIP transcription factor 2	Homo sapiens	143-147
25451255-2	2014	We previously demonstrated that the single N-glycan deletion mutant of soluble ErbB3 protein (sErbB3 N418Q) attenuates heregulin beta1-induced ErbB3 signaling.	n-glycan	43-51	erb-b2 receptor tyrosine kinase 3	Homo sapiens	79-84
25451255-2	2014	We previously demonstrated that the single N-glycan deletion mutant of soluble ErbB3 protein (sErbB3 N418Q) attenuates heregulin beta1-induced ErbB3 signaling.	n-glycan	43-51	erb-b2 receptor tyrosine kinase 3	Homo sapiens	95-100
25263124-5	2014	N-glycan branching was required for positive selection and decoupled Lck signaling from TCR-driven Ca(2+) flux to simultaneously promote low-affinity peptide-MHC responses while inhibiting high-affinity ones.	n-glycan	0-8	LCK proto-oncogene, Src family tyrosine kinase	Homo sapiens	69-72
25142936-0	2014	The non-classical N-glycan processing pathway of bovine brain ecto-nucleotide phosphodiesterase/pyrophosphatase 6 (eNPP6) is brain specific and not due to mannose-6-phosphorylation.	n-glycan	18-26	ectonucleotide pyrophosphatase/phosphodiesterase 6	Bos taurus	115-120
25004930-8	2014	Fab N-glycan sialylation was increased and bisection was decreased relative to postpartum time points, and nearly complete galactosylation of Fab glycans was observed throughout.	n-glycan	4-12	FA complementation group B	Homo sapiens	0-3
25263124-3	2014	We report that N-glycan branching of TCR and the CD4 and CD8 coreceptors separately altered the upper and lower affinity boundaries from which interactions between peptide-MHC and TCR positively select T cells.	n-glycan	15-23	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	37-40
25263124-5	2014	N-glycan branching was required for positive selection and decoupled Lck signaling from TCR-driven Ca(2+) flux to simultaneously promote low-affinity peptide-MHC responses while inhibiting high-affinity ones.	n-glycan	0-8	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	88-91
25263124-3	2014	We report that N-glycan branching of TCR and the CD4 and CD8 coreceptors separately altered the upper and lower affinity boundaries from which interactions between peptide-MHC and TCR positively select T cells.	n-glycan	15-23	CD4 molecule	Homo sapiens	49-52
25263124-3	2014	We report that N-glycan branching of TCR and the CD4 and CD8 coreceptors separately altered the upper and lower affinity boundaries from which interactions between peptide-MHC and TCR positively select T cells.	n-glycan	15-23	CD8a molecule	Homo sapiens	57-60
25263124-6	2014	Therefore, N-glycan branching imposes a sliding scale on interactions between peptide-MHC and TCR that bidirectionally expands the affinity range for positive selection.	n-glycan	11-19	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	94-97
25263124-3	2014	We report that N-glycan branching of TCR and the CD4 and CD8 coreceptors separately altered the upper and lower affinity boundaries from which interactions between peptide-MHC and TCR positively select T cells.	n-glycan	15-23	T cell receptor beta variable 20/OR9-2 (non-functional)	Homo sapiens	180-183
25135639-2	2014	Our previous study showed that N-glycan alpha2,6-sialylation regulates the cell surface residency of an anti-apoptotic molecule, platelet endothelial cell adhesion molecule (PECAM), as well as the sensitivity of endothelial cells toward apoptotic stimuli.	n-glycan	31-39	platelet and endothelial cell adhesion molecule 1	Homo sapiens	129-172
25179596-4	2014	Using RPE and KPT cell lines, and AP-1B-knockdown MDCK cells, we show that mutation of the N-glycan linked to N727 in the basolateral marker transferrin receptor (TfR) or knockdown of galectin-4 inhibits TfR transcytosis to apical recycling endosomes and the apical plasma membrane, and promotes TfR lysosomal targeting and subsequent degradation.	n-glycan	91-99	transferrin receptor	Canis lupus familiaris	141-161
25179596-4	2014	Using RPE and KPT cell lines, and AP-1B-knockdown MDCK cells, we show that mutation of the N-glycan linked to N727 in the basolateral marker transferrin receptor (TfR) or knockdown of galectin-4 inhibits TfR transcytosis to apical recycling endosomes and the apical plasma membrane, and promotes TfR lysosomal targeting and subsequent degradation.	n-glycan	91-99	transferrin receptor	Canis lupus familiaris	163-166
25179596-4	2014	Using RPE and KPT cell lines, and AP-1B-knockdown MDCK cells, we show that mutation of the N-glycan linked to N727 in the basolateral marker transferrin receptor (TfR) or knockdown of galectin-4 inhibits TfR transcytosis to apical recycling endosomes and the apical plasma membrane, and promotes TfR lysosomal targeting and subsequent degradation.	n-glycan	91-99	transferrin receptor	Canis lupus familiaris	204-207
25179596-4	2014	Using RPE and KPT cell lines, and AP-1B-knockdown MDCK cells, we show that mutation of the N-glycan linked to N727 in the basolateral marker transferrin receptor (TfR) or knockdown of galectin-4 inhibits TfR transcytosis to apical recycling endosomes and the apical plasma membrane, and promotes TfR lysosomal targeting and subsequent degradation.	n-glycan	91-99	transferrin receptor	Canis lupus familiaris	204-207
25199692-0	2014	Restricted motion of the conserved immunoglobulin G1 N-glycan is essential for efficient FcgammaRIIIa binding.	n-glycan	53-61	Fc gamma receptor IIIa	Homo sapiens	89-101
25199692-4	2014	Here we identify a link between motion of the N-glycan and Fc:FcgammaRIIIa affinity that explains the N-glycan requirement.	n-glycan	46-54	Fc gamma receptor IIIa	Homo sapiens	62-74
25199692-4	2014	Here we identify a link between motion of the N-glycan and Fc:FcgammaRIIIa affinity that explains the N-glycan requirement.	n-glycan	102-110	Fc gamma receptor IIIa	Homo sapiens	62-74
25135639-2	2014	Our previous study showed that N-glycan alpha2,6-sialylation regulates the cell surface residency of an anti-apoptotic molecule, platelet endothelial cell adhesion molecule (PECAM), as well as the sensitivity of endothelial cells toward apoptotic stimuli.	n-glycan	31-39	platelet and endothelial cell adhesion molecule 1	Homo sapiens	174-179
25135639-6	2014	Furthermore, we found that a cluster-type alpha2,6-sialyl N-glycan probe specifically bound to PECAM-immobilized beads.	n-glycan	58-66	platelet and endothelial cell adhesion molecule 1	Homo sapiens	95-100
24942734-0	2014	A hyaluronan receptor for endocytosis (HARE) link domain N-glycan is required for extracellular signal-regulated kinase (ERK) and nuclear factor-kappaB (NF-kappaB) signaling in response to the uptake of hyaluronan but not heparin, dermatan sulfate, or acetylated low density lipoprotein (LDL).	n-glycan	57-65	stabilin 2	Homo sapiens	2-37
24970053-11	2014	Our findings suggest that beta3GnT8 affects the signal transduction pathway of MMP-2 by altering the N-glycan structure of CD147.	n-glycan	101-109	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	Homo sapiens	26-35
24970053-11	2014	Our findings suggest that beta3GnT8 affects the signal transduction pathway of MMP-2 by altering the N-glycan structure of CD147.	n-glycan	101-109	matrix metallopeptidase 2	Homo sapiens	79-84
24970053-11	2014	Our findings suggest that beta3GnT8 affects the signal transduction pathway of MMP-2 by altering the N-glycan structure of CD147.	n-glycan	101-109	basigin (Ok blood group)	Homo sapiens	123-128
25238750-5	2014	GFP-KOR1 variants with a single N-glycan at nonconserved sites were less effective than those with one at a highly conserved site in rescuing the root growth phenotype of rsw2-1 (kor1 allele).	n-glycan	32-40	glycosyl hydrolase 9A1	Arabidopsis thaliana	0-8
25238750-5	2014	GFP-KOR1 variants with a single N-glycan at nonconserved sites were less effective than those with one at a highly conserved site in rescuing the root growth phenotype of rsw2-1 (kor1 allele).	n-glycan	32-40	glycosyl hydrolase 9A1	Arabidopsis thaliana	179-183
25149452-3	2014	Here, we show that the innate immune receptor Dectin-1 expressed on dendritic cells and macrophages is critical to NK-mediated killing of tumor cells that express N-glycan structures at high levels.	n-glycan	163-171	C-type lectin domain family 7, member a	Mus musculus	46-54
24913443-10	2014	Taken together, the present study reveals a novel mechanism of GnT-V as a suppressor of both EMT and invasion in human lung cancer cells, which may be useful for fully understanding N-glycan"s biological roles in lung cancer progression.	n-glycan	182-190	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	63-68
24913443-10	2014	Taken together, the present study reveals a novel mechanism of GnT-V as a suppressor of both EMT and invasion in human lung cancer cells, which may be useful for fully understanding N-glycan"s biological roles in lung cancer progression.	n-glycan	182-190	IL2 inducible T cell kinase	Homo sapiens	93-96
24859049-6	2014	These experiments showed that viral entry of R5-tropic viruses lacking the N-glycan g15 within the V3 loop was inhibited by CCR5-tropic sgp120 harboring the g15 N-glycan.	n-glycan	75-83	C-C motif chemokine receptor 5	Homo sapiens	124-128
24859049-6	2014	These experiments showed that viral entry of R5-tropic viruses lacking the N-glycan g15 within the V3 loop was inhibited by CCR5-tropic sgp120 harboring the g15 N-glycan.	n-glycan	161-169	C-C motif chemokine receptor 5	Homo sapiens	124-128
24855066-8	2014	These N-glycan changes were verified by examining gene transcript levels of the enzymes specific for their synthesis (MGAT3, ST6GAL1, and B4GALNT3) using qRT-PCR.	n-glycan	6-14	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	118-123
24855066-8	2014	These N-glycan changes were verified by examining gene transcript levels of the enzymes specific for their synthesis (MGAT3, ST6GAL1, and B4GALNT3) using qRT-PCR.	n-glycan	6-14	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	125-132
24855066-8	2014	These N-glycan changes were verified by examining gene transcript levels of the enzymes specific for their synthesis (MGAT3, ST6GAL1, and B4GALNT3) using qRT-PCR.	n-glycan	6-14	beta-1,4-N-acetyl-galactosaminyltransferase 3	Homo sapiens	138-146
24618259-8	2014	Biochemical analyses and live-cell imaging experiments indicated that impaired N-glycan processing is due to aberrant deposition of rBChE oligomers in the endoplasmic reticulum or endoplasmic-reticulum-derived compartments.	n-glycan	79-87	butyrylcholinesterase	Rattus norvegicus	132-137
24942734-11	2014	We conclude that a Link domain complex N-glycan is required specifically for HARE HA-mediated activation of ERK1/2 and NF-kappaB-mediated gene expression and that this initial activation mechanism is different from and independent of the initial mechanisms for HARE-mediated signaling in response to Hep, AcLDL, or DS uptake.	n-glycan	39-47	mitogen-activated protein kinase 3	Homo sapiens	108-114
24726881-7	2014	GnT-III and GnT-V activities were assayed with a novel HPLC method based on labeling of N-glycan acceptor with 2-aminobenzamide (adapted from Taniguchi et al., 1989).	n-glycan	88-96	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-7
24726881-7	2014	GnT-III and GnT-V activities were assayed with a novel HPLC method based on labeling of N-glycan acceptor with 2-aminobenzamide (adapted from Taniguchi et al., 1989).	n-glycan	88-96	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	12-17
24780636-0	2014	Structural change of N-glycan exposes hydrophobic surface of human transferrin.	n-glycan	21-29	transferrin	Homo sapiens	67-78
24780636-9	2014	These results suggest that the different N-glycan structure of Tf-1 lowers the apparent hydration volume and reveals a patch of hydrophobic surface on transferrin which is otherwise covered with sialoglycan in sTf and Tf-2.	n-glycan	41-49	transferrin	Homo sapiens	151-162
24723043-0	2014	alpha-Klotho mice demonstrate increased expression of the non-sulfated N-glycan form of the HNK-1 glyco-epitope in kidney tissue.	n-glycan	71-79	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)	Mus musculus	92-97
24623697-0	2014	Characterization of N-glycan heterogeneities of erythropoietin products by liquid chromatography/mass spectrometry and multivariate analysis.	n-glycan	20-28	erythropoietin	Homo sapiens	48-62
25030450-7	2014	N-glycan removal or neutralization leads to larger membrane exploration and reduced interaction with clathrin, compromising clathrin-dependent internalization of virus-like particles by DC-SIGN.	n-glycan	0-8	CD209 molecule	Homo sapiens	186-193
24904006-8	2014	In addition, the polar BCN derivatives label the N-glycan of the membrane calcium channel TRPV5 in HEK293 cells with significantly enhanced signal-to-noise ratios.	n-glycan	49-57	transient receptor potential cation channel subfamily V member 5	Homo sapiens	90-95
25101107-4	2014	Some of these complex N-glycan modifications like the presence of beta1,2-xylose, core alpha1,3-fucose or the Lewis a-epitope are characteristic for plants and are evolutionary highly conserved.	n-glycan	22-30	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	66-73
24967714-0	2014	Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.	n-glycan	33-41	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	61-66
24967714-0	2014	Deletion of the highly conserved N-glycan at Asn260 of HIV-1 gp120 affects folding and lysosomal degradation of gp120, and results in loss of viral infectivity.	n-glycan	33-41	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	112-117
24798333-6	2014	The turnover of receptors associating with the molecular chaperone calnexin (CNX) was significantly slower for the hdeltaOR-Cys(27), pointing to an important role of CNX in the hdeltaOR N-glycan-dependent QC.	n-glycan	186-194	calnexin	Homo sapiens	67-75
24798333-6	2014	The turnover of receptors associating with the molecular chaperone calnexin (CNX) was significantly slower for the hdeltaOR-Cys(27), pointing to an important role of CNX in the hdeltaOR N-glycan-dependent QC.	n-glycan	186-194	calnexin	Homo sapiens	77-80
24798333-6	2014	The turnover of receptors associating with the molecular chaperone calnexin (CNX) was significantly slower for the hdeltaOR-Cys(27), pointing to an important role of CNX in the hdeltaOR N-glycan-dependent QC.	n-glycan	186-194	calnexin	Homo sapiens	166-169
24798333-9	2014	Taken together, the hdeltaOR appears to rely primarily on the CNX-mediated N-glycan-dependent QC that has the capacity to assist in folding, whereas the N-glycan-independent mechanism constitutes an alternative, although less accurate, system for directing misfolded/incompletely folded receptors to ERAD, possibly in altered cellular conditions.	n-glycan	75-83	calnexin	Homo sapiens	62-65
24742675-0	2014	N-glycan remodeling on glucagon receptor is an effector of nutrient sensing by the hexosamine biosynthesis pathway.	n-glycan	0-8	glucagon receptor	Homo sapiens	23-40
24742675-8	2014	Our results reveal that the hexosamine biosynthesis pathway and GlcNAc salvage contribute to glucose homeostasis through N-glycan branching on glucagon receptor.	n-glycan	121-129	glucagon receptor	Homo sapiens	143-160
24403309-7	2014	B4GALT3 expression altered glycosylation on the N-glycan of beta1 integrin probably through changes in poly-N-acetyllactosamine expression.	n-glycan	48-56	beta-1,4-galactosyltransferase 3	Homo sapiens	0-7
24403309-7	2014	B4GALT3 expression altered glycosylation on the N-glycan of beta1 integrin probably through changes in poly-N-acetyllactosamine expression.	n-glycan	48-56	integrin subunit beta 1	Homo sapiens	60-74
24355574-1	2014	Human erythropoietin produced in the egg white of chimeric chicken contains N-glycan with lower amounts of terminal galactose and sialic acid; therefore, the chicken galactosyltransferase gene was introduced together with the human erythropoietin gene by a retroviral vector.	n-glycan	76-84	erythropoietin	Homo sapiens	6-20
24725217-10	2014	The smallest amount of the N-glycan characterized by 3DCC was approximately 400 pmol (836 ng).	n-glycan	27-35	DCC netrin 1 receptor	Homo sapiens	54-57
24785692-0	2014	Mutations in four glycosyl hydrolases reveal a highly coordinated pathway for rhodopsin biosynthesis and N-glycan trimming in Drosophila melanogaster.	n-glycan	105-113	neither inactivation nor afterpotential E	Drosophila melanogaster	78-87
24785692-4	2014	The major rhodopsin in Drosophila melanogaster photoreceptors, Rh1, is highly unique among glycoproteins, as the N-glycan appears to be completely removed during Rh1 biosynthesis and maturation.	n-glycan	113-121	neither inactivation nor afterpotential E	Drosophila melanogaster	10-19
24785692-4	2014	The major rhodopsin in Drosophila melanogaster photoreceptors, Rh1, is highly unique among glycoproteins, as the N-glycan appears to be completely removed during Rh1 biosynthesis and maturation.	n-glycan	113-121	neither inactivation nor afterpotential E	Drosophila melanogaster	63-66
24785692-9	2014	Also of significance, our results indicate that Hexo1 has a biosynthetic role in N-glycan processing during Rh1 maturation.	n-glycan	81-89	neither inactivation nor afterpotential E	Drosophila melanogaster	108-111
24785692-11	2014	Here, we present a genetic dissection of glycoprotein processing in Drosophila and unveil key steps in N-glycan trimming during Rh1 biosynthesis.	n-glycan	103-111	neither inactivation nor afterpotential E	Drosophila melanogaster	128-131
23898885-5	2013	The N-glycan profile showed that cgl-derived IDUA contained predominantly high-mannose-type N-glycans (94.5%), and the residual complex/hybrid N-glycan-containing enzyme was efficiently removed by an additional affinity chromatography step.	n-glycan	4-12	alpha-L-iduronidase	Homo sapiens	45-49
24508628-4	2014	The abnormal "type-1" transferrin glycoform pattern indicated a defect in N-glycan assembly occurring in congenital disorders of glycosylation (CDG), a family of rare inherited metabolic disorders.	n-glycan	74-82	transferrin	Homo sapiens	22-33
24737672-7	2014	Thus, MNS4 and MNS5 function in the formation of unique N-glycan structures that are specifically recognized by other components of the ERAD machinery, which ultimately results in the disposal of misfolded glycoproteins.	n-glycan	56-64	Glycosyl hydrolase family 47 protein	Arabidopsis thaliana	6-10
24737672-7	2014	Thus, MNS4 and MNS5 function in the formation of unique N-glycan structures that are specifically recognized by other components of the ERAD machinery, which ultimately results in the disposal of misfolded glycoproteins.	n-glycan	56-64	Glycosyl hydrolase family 47 protein	Arabidopsis thaliana	15-19
24399258-1	2014	N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins and the dysfunction of which is a common feature of various carcinomas.	n-glycan	154-162	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-33
24399258-1	2014	N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins and the dysfunction of which is a common feature of various carcinomas.	n-glycan	154-162	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-40
24399258-1	2014	N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins and the dysfunction of which is a common feature of various carcinomas.	n-glycan	154-162	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	70-77
24295106-8	2014	Downregulation of Man1alpha1 and Mgat1 in LIM1215 also coincided with the higher degree of incomplete N-glycan processing and accumulation of high mannose type structures as well as bisecting N-glycans when compared to the other two cell lines.	n-glycan	102-110	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	33-38
25056432-0	2014	Rho GTPase Rac1: molecular switch within the galectin network and for N-glycan alpha2,6-sialylation/O-glycan core 1 sialylation in colon cancer in vitro.	n-glycan	70-78	Rac family small GTPase 1	Homo sapiens	11-15
23868388-5	2013	Lectin blot showed the existence of alpha2,6-sialic acid on TNFR/Fc, which disappeared with the removal of N-glycan by PNGase.	n-glycan	107-115	N-glycanase 1	Gallus gallus	119-125
24619415-4	2014	In this study, we show that, in mouse embryonic fibroblasts (MEFs) from Fut8(-/-) mice, another N-glycan branching structure, bisecting GlcNAc, is specifically up-regulated by enhanced gene expression of the responsible enzyme N-acetylglucosaminyltransferase III (GnT-III).	n-glycan	96-104	fucosyltransferase 8	Mus musculus	72-76
24619415-4	2014	In this study, we show that, in mouse embryonic fibroblasts (MEFs) from Fut8(-/-) mice, another N-glycan branching structure, bisecting GlcNAc, is specifically up-regulated by enhanced gene expression of the responsible enzyme N-acetylglucosaminyltransferase III (GnT-III).	n-glycan	96-104	mannoside acetylglucosaminyltransferase 3	Mus musculus	264-271
24365146-5	2014	These findings indicate that glycosylation and subsequent N-glycan maturation of Nox1 are both dispensable for its cell surface recruitment.	n-glycan	58-66	NADPH oxidase 1	Homo sapiens	81-85
25040827-0	2014	Structural determination of an N-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.	n-glycan	31-39	prothoracicotropic hormone	Bombyx mori	63-89
25040827-1	2014	The predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manalpha1-6Manbeta1-4GlcNAcbeta1-4(Fucalpha1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH.	n-glycan	33-41	prothoracicotropic hormone	Bombyx mori	49-75
25040827-1	2014	The predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manalpha1-6Manbeta1-4GlcNAcbeta1-4(Fucalpha1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH.	n-glycan	33-41	prothoracicotropic hormone	Bombyx mori	77-81
25040827-1	2014	The predominant structure of the N-glycan on the prothoracicotropic hormone (PTTH) isolated from 1.8 million adult heads of silkmoths was determined to be Manalpha1-6Manbeta1-4GlcNAcbeta1-4(Fucalpha1-6)GlcNAc-OH, which is identical to that of the baculovirus-expressed recombinant PTTH.	n-glycan	33-41	prothoracicotropic hormone	Bombyx mori	281-285
23898885-5	2013	The N-glycan profile showed that cgl-derived IDUA contained predominantly high-mannose-type N-glycans (94.5%), and the residual complex/hybrid N-glycan-containing enzyme was efficiently removed by an additional affinity chromatography step.	n-glycan	92-100	alpha-L-iduronidase	Homo sapiens	45-49
24155237-0	2013	Enzymatic basis for N-glycan sialylation: structure of rat alpha2,6-sialyltransferase (ST6GAL1) reveals conserved and unique features for glycan sialylation.	n-glycan	20-28	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Rattus norvegicus	87-94
24108122-3	2013	Here, we report the crystal structures of the mDCIR2 carbohydrate recognition domain in unliganded form as well as in complex with an agalactosylated complex-type N-glycan unit carrying a bisecting GlcNAc residue.	n-glycan	163-171	C-type lectin domain family 4, member a4	Mus musculus	46-52
23688399-3	2013	The two enzymes have similar enzymatic properties and structures but display different acceptor specificities: FUT8 and NodZ prefer N-glycan and chitooligosaccharide, respectively.	n-glycan	132-140	fucosyltransferase 8	Homo sapiens	111-115
24031089-10	2013	With this study, we add SLC35A3 to the gene list of autism spectrum disorders, and underscore the crucial importance of UDP-GlcNAc in the regulation of the N-glycan branching pathway in the Golgi apparatus.	n-glycan	156-164	solute carrier family 35 member A3	Homo sapiens	24-31
23970553-2	2013	The channel is glycosylated with a complex type N-glycan and it has been postulated that hydrolysis of the terminal sialic acid(s) stimulate TRPV5 activity.	n-glycan	48-56	transient receptor potential cation channel subfamily V member 5	Homo sapiens	141-146
23970553-3	2013	The present study delineates the role of the N-glycan in TRPV5 activity using biochemical assays in Human Embryonic Kidney 293 cells expressing TRPV5, isoelectric focusing and total internal reflection fluorescent microscopy.	n-glycan	45-53	transient receptor potential cation channel subfamily V member 5	Homo sapiens	57-62
24097984-0	2013	Suppression of heregulin beta signaling by the single N-glycan deletion mutant of soluble ErbB3 protein.	n-glycan	54-62	erb-b2 receptor tyrosine kinase 3	Homo sapiens	90-95
24097984-9	2013	Results suggested that the N-glycan-deleted mutant of sErbB3 suppresses heregulin signaling via ErbB3-containing heterodimers more effectively than the wild type.	n-glycan	27-35	erb-b2 receptor tyrosine kinase 3	Homo sapiens	55-60
23970553-5	2013	Klotho was found to increase the plasma membrane stability of TRPV5, via the TRPV5 N-glycan.	n-glycan	83-91	klotho	Homo sapiens	0-6
23970553-5	2013	Klotho was found to increase the plasma membrane stability of TRPV5, via the TRPV5 N-glycan.	n-glycan	83-91	transient receptor potential cation channel subfamily V member 5	Homo sapiens	62-67
23970553-5	2013	Klotho was found to increase the plasma membrane stability of TRPV5, via the TRPV5 N-glycan.	n-glycan	83-91	transient receptor potential cation channel subfamily V member 5	Homo sapiens	77-82
23970553-9	2013	In addition, sialidase modified the N-glycan of transferrin, a model glycoprotein, differently from klotho.	n-glycan	36-44	transferrin	Homo sapiens	48-59
23970553-10	2013	Previous studies showed that after klotho treatment, galectin-1 binds the TRPV5 N-glycan and thereby increases TRPV5 activity.	n-glycan	80-88	klotho	Homo sapiens	35-41
23970553-10	2013	Previous studies showed that after klotho treatment, galectin-1 binds the TRPV5 N-glycan and thereby increases TRPV5 activity.	n-glycan	80-88	galectin 1	Homo sapiens	53-63
23970553-10	2013	Previous studies showed that after klotho treatment, galectin-1 binds the TRPV5 N-glycan and thereby increases TRPV5 activity.	n-glycan	80-88	transient receptor potential cation channel subfamily V member 5	Homo sapiens	74-79
23970553-13	2013	In conclusion, two distinct TRPV5 stimulatory mechanisms were demonstrated; a klotho-mediated effect that is dependent on the N-glycan of TRPV5 and a sialidase-mediated stimulation that is lipid raft-dependent and independent of the N-glycan of TRPV5.	n-glycan	126-134	transient receptor potential cation channel subfamily V member 5	Homo sapiens	28-33
23970553-13	2013	In conclusion, two distinct TRPV5 stimulatory mechanisms were demonstrated; a klotho-mediated effect that is dependent on the N-glycan of TRPV5 and a sialidase-mediated stimulation that is lipid raft-dependent and independent of the N-glycan of TRPV5.	n-glycan	126-134	klotho	Homo sapiens	78-84
23970553-13	2013	In conclusion, two distinct TRPV5 stimulatory mechanisms were demonstrated; a klotho-mediated effect that is dependent on the N-glycan of TRPV5 and a sialidase-mediated stimulation that is lipid raft-dependent and independent of the N-glycan of TRPV5.	n-glycan	233-241	transient receptor potential cation channel subfamily V member 5	Homo sapiens	28-33
23836288-10	2013	Taken together, these studies in C. elegans demonstrate that decreased ER alpha-glucosidase I affects the entire N-glycan profile and induces chronic ER stress, which may contribute to the pathophysiology of CDG-IIb in humans.	n-glycan	113-121	LOW QUALITY PROTEIN: mannosyl-oligosaccharide glucosidase	Cricetulus griseus	74-93
23868473-0	2013	Chemoenzymatic synthesis of the immunoglobulin domain of Tim-3 carrying a complex-type N-glycan by using a one-pot ligation.	n-glycan	87-95	hepatitis A virus cellular receptor 2	Homo sapiens	57-62
23959878-0	2013	Human alpha-L-iduronidase uses its own N-glycan as a substrate-binding and catalytic module.	n-glycan	39-47	alpha-L-iduronidase	Homo sapiens	6-25
23901877-6	2013	We focused on the trisialylated N-glycan fraction from haptoglobin and human plasma, enriched using weak anion exchange chromatography, as this trisialylated fraction has been linked with cancer associated changes in the serum N-glycome.	n-glycan	32-40	haptoglobin	Homo sapiens	55-66
23959878-3	2013	Here, we show that human alpha-l-iduronidase (hIDUA), of which a dysfunction causes accumulation of dermatan/heparan sulfate leading to mucopolysaccharidosis type I, uses its own N-glycan as a substrate binding and catalytic module.	n-glycan	179-187	alpha-L-iduronidase	Homo sapiens	25-44
23959878-3	2013	Here, we show that human alpha-l-iduronidase (hIDUA), of which a dysfunction causes accumulation of dermatan/heparan sulfate leading to mucopolysaccharidosis type I, uses its own N-glycan as a substrate binding and catalytic module.	n-glycan	179-187	alpha-L-iduronidase	Homo sapiens	46-51
23959878-6	2013	The kinetics of native and deglycosylated hIDUA suggested that the N-glycan is also involved in catalytic processes.	n-glycan	67-75	alpha-L-iduronidase	Homo sapiens	42-47
23799331-3	2013	Here we give an overview about inducers, importance, and relevance of anti-N-Glycan CCD IgE antibodies.	n-glycan	75-83	immunoglobulin heavy constant epsilon	Homo sapiens	88-91
23777858-2	2013	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1, also called GnTI) adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) N-glycan structure as part of complex N-glycan synthesis.	n-glycan	153-161	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Cricetulus griseus	77-82
23777858-2	2013	Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1, also called GnTI) adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) N-glycan structure as part of complex N-glycan synthesis.	n-glycan	191-199	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Cricetulus griseus	77-82
23718681-2	2013	Mutations in N-glycosylation consensus sites (NXT and NXS, where X P) that alter the kinetics of the initial N-glycan attachment have been associated with cardiac arrhythmias; however, the molecular determinants that define co- and post-translational consensus sites in proteins are not known.	n-glycan	109-117	nuclear transport factor 2 like export factor 1	Homo sapiens	46-49
24386838-1	2013	To determine the functions of N-carbohydrate chains in human parainfluenza virus type 3 hemagglutinin-neuraminidase(HN) protein, a PCR-based site-directed mutagenesis method was used to obtain N-glycan mutants.	n-glycan	193-201	neuraminidase 1	Homo sapiens	102-115
23815085-5	2013	Analysis of the N-glycan structures showed that SF9 TIMP-1 has the simplest N-glycan structures, followed by fibroblast TIMP-1 and 293 TIMP-1, in order of increasing complexity in their N-glycan structures.	n-glycan	16-24	TIMP metallopeptidase inhibitor 1	Homo sapiens	52-58
23815085-5	2013	Analysis of the N-glycan structures showed that SF9 TIMP-1 has the simplest N-glycan structures, followed by fibroblast TIMP-1 and 293 TIMP-1, in order of increasing complexity in their N-glycan structures.	n-glycan	76-84	TIMP metallopeptidase inhibitor 1	Homo sapiens	52-58
23815085-5	2013	Analysis of the N-glycan structures showed that SF9 TIMP-1 has the simplest N-glycan structures, followed by fibroblast TIMP-1 and 293 TIMP-1, in order of increasing complexity in their N-glycan structures.	n-glycan	76-84	TIMP metallopeptidase inhibitor 1	Homo sapiens	52-58
23900214-5	2013	N-glycan profiles both basally and with stimulation were also bed specific, with hypoglycosylated N-glycans correlating with increased THP-1 monocyte adhesion.	n-glycan	0-8	GLI family zinc finger 2	Homo sapiens	135-140
23879813-4	2013	Voglibose is a representative antidiabetic drug possessing inhibitory activity towards human alpha-glucosidase; it blocked the proper N-glycan modification of tyrosinase, resulting in a dramatic reduction of the tyrosinase protein level by altering its stability and subsequently decreasing melanin production.	n-glycan	134-142	tyrosinase	Homo sapiens	159-169
23550150-6	2013	These observations reveal a distinct role for the N-glycan binding of ERGIC-53 in the receptor-mediated ER exit of newly synthesized Mac-2BP in the early secretion pathway.	n-glycan	50-58	lectin, mannose binding 1	Homo sapiens	70-78
23550150-0	2013	Regulation of Mac-2BP secretion is mediated by its N-glycan binding to ERGIC-53.	n-glycan	51-59	galectin 3 binding protein	Homo sapiens	14-21
23776238-0	2013	B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention.	n-glycan	50-58	TNF receptor superfamily member 17	Homo sapiens	0-25
23550150-6	2013	These observations reveal a distinct role for the N-glycan binding of ERGIC-53 in the receptor-mediated ER exit of newly synthesized Mac-2BP in the early secretion pathway.	n-glycan	50-58	galectin 3 binding protein	Homo sapiens	133-140
23065139-0	2013	N-glycan analysis of human alpha1-antitrypsin produced in Chinese hamster ovary cells.	n-glycan	0-8	alpha-1-antitrypsin	Cricetulus griseus	27-45
23550150-0	2013	Regulation of Mac-2BP secretion is mediated by its N-glycan binding to ERGIC-53.	n-glycan	51-59	lectin, mannose binding 1	Homo sapiens	71-79
23548572-2	2013	We previously reported that GnT-IVa glycosyltransferase is required for the production of an N-glycan structure that acts as a ligand for galectins to form the glycan-galectin lattice that maintains the stable cell surface expression of GLUT2, and cellular glucose transport activity, although the functional relevance of the N-glycosylation of GLUT2 to its membrane sub-domain distribution is not fully understood.	n-glycan	93-101	solute carrier family 2 member 2	Homo sapiens	237-242
23668542-7	2013	The N-glycan profile of the recombinant A1AT variants was mostly composed of monofucosylated bi-, tri-, and tetraantennary complex-type N-glycans, with a tendency toward higher antennary structures compared to the wild-type.	n-glycan	4-12	serpin family A member 1	Homo sapiens	40-44
23594311-2	2013	Golgi N-glycan branching enzymes produce N-glycans, using UDP-GlcNAc as a substrate, which attach to the T cell receptor (TCR) and cytotoxic T-lymphocyte antigen-4 (CTLA-4).	n-glycan	6-14	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	131-163
23594311-2	2013	Golgi N-glycan branching enzymes produce N-glycans, using UDP-GlcNAc as a substrate, which attach to the T cell receptor (TCR) and cytotoxic T-lymphocyte antigen-4 (CTLA-4).	n-glycan	6-14	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	165-171
23658022-5	2013	The AE1-Ly49E chimeric protein possessing the PhiXPhiXPhi motif exhibited effective cell surface expression and N-glycan maturation via the coatomer protein complex II pathway, whereas a chimera lacking this motif was retained in the ER.	n-glycan	112-120	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	4-7
23297157-6	2013	In this study, capillary gel electrophoresis with laser-induced fluorescence detection (CGE-LIF) based glycoanalysis (N-glycan fingerprinting) was used to determine the impact of cultivation conditions on the HA N-glycosylation pattern of Madin-Darby canine kidney (MDCK) cell-derived influenza virus A PR/8/34 (H1N1).	n-glycan	118-126	LIF interleukin 6 family cytokine	Canis lupus familiaris	92-95
23548572-2	2013	We previously reported that GnT-IVa glycosyltransferase is required for the production of an N-glycan structure that acts as a ligand for galectins to form the glycan-galectin lattice that maintains the stable cell surface expression of GLUT2, and cellular glucose transport activity, although the functional relevance of the N-glycosylation of GLUT2 to its membrane sub-domain distribution is not fully understood.	n-glycan	93-101	solute carrier family 2 member 2	Homo sapiens	345-350
23585889-3	2013	We identified calreticulin as novel amyloid precursor protein interaction partner that binds to the gamma-secretase cleavage site within amyloid precursor protein and showed that this Ca(2+)- and N-glycan-independent interaction is mediated by amino acids 330-344 in the C-terminal C-domain of calreticulin.	n-glycan	196-204	calreticulin	Homo sapiens	14-26
23441047-5	2013	Further analysis of the N-glycan regulation by tunicamycin (TM) application or PNGase F treatment in MCF/ADR cells showed partial inhibition of the N-glycan biosynthesis and increased sensitivity to chemotherapeutic drugs dramatically both in vitro and in vivo.	n-glycan	24-32	N-glycanase 1	Homo sapiens	79-85
23441047-5	2013	Further analysis of the N-glycan regulation by tunicamycin (TM) application or PNGase F treatment in MCF/ADR cells showed partial inhibition of the N-glycan biosynthesis and increased sensitivity to chemotherapeutic drugs dramatically both in vitro and in vivo.	n-glycan	148-156	N-glycanase 1	Homo sapiens	79-85
22544341-0	2013	L1CAM from human melanoma carries a novel type of N-glycan with Galbeta1-4Galbeta1- motif.	n-glycan	50-58	L1 cell adhesion molecule	Homo sapiens	0-5
23107376-1	2013	Aberrant beta1, 6-N-acetylglucosaminyltransferase V (MGAT5) expression in malignant tissues has been reported to be involved in the development of various cancers and their progression, through altering N-glycan branching.	n-glycan	203-211	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	9-51
23671930-4	2013	We have previously demonstrated the existence of a bi-directional cross-talk between E-cadherin and two major N-glycan processing enzymes, N-acetylglucosaminyltransferase-III or -V (GnT-III or GnT-V).	n-glycan	110-118	cadherin 1	Homo sapiens	85-95
23671930-4	2013	We have previously demonstrated the existence of a bi-directional cross-talk between E-cadherin and two major N-glycan processing enzymes, N-acetylglucosaminyltransferase-III or -V (GnT-III or GnT-V).	n-glycan	110-118	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	139-180
23671930-4	2013	We have previously demonstrated the existence of a bi-directional cross-talk between E-cadherin and two major N-glycan processing enzymes, N-acetylglucosaminyltransferase-III or -V (GnT-III or GnT-V).	n-glycan	110-118	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	193-198
23351704-4	2013	Here we describe linked intronic variants of MGAT5 that are associated with reduced N-glycan branching, CTLA-4 surface expression and MS (p=5.79x10(-9), n=7,741), the latter additive with the MGAT1, IL2RA and IL7RA MS risk variants (p=1.76x10(-9), OR=0.67-1.83, n=3,518).	n-glycan	84-92	mannoside acetylglucosaminyltransferase 5	Mus musculus	45-50
23319596-10	2013	These results suggest that the N-glycan at Asn-644 of hLOXL2 enhances the solubility and stability of the LOX catalytic domain.	n-glycan	31-39	lysyl oxidase like 2	Homo sapiens	54-60
23319596-10	2013	These results suggest that the N-glycan at Asn-644 of hLOXL2 enhances the solubility and stability of the LOX catalytic domain.	n-glycan	31-39	lysyl oxidase	Homo sapiens	55-58
23107376-1	2013	Aberrant beta1, 6-N-acetylglucosaminyltransferase V (MGAT5) expression in malignant tissues has been reported to be involved in the development of various cancers and their progression, through altering N-glycan branching.	n-glycan	203-211	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	53-58
23201481-6	2013	Important sorting determinant for these processes proved to be N-glycan moieties that are required for the prevention of terminal misfolding and aggregation of clusterin in the endoplasmic reticulum.	n-glycan	63-71	clusterin	Homo sapiens	160-169
23151259-8	2013	N-Glycan profiles from serum and plasma samples differed largely in glycans identified in fibrinogen, suggesting that this glycoprotein represents a major factor distinguishing these body fluids.	n-glycan	0-8	fibrinogen beta chain	Homo sapiens	90-100
23475714-8	2013	The presence of short N-glycan structures is explained by the low level of N-acetylglucosaminyltransferase I (GNT-I) activity and the absence of several other glycosyltransferases, such as GNT-II and beta1,4-galactosyltransferase I (beta1,4GalTI), and of sialyltransferases.In this chapter, we show that the glycosylation pathway of a lepidopteran cell line can be modified via infection with an engineered baculovirus to "humanize" the glycosylation pattern of a recombinant protein.	n-glycan	22-30	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	110-115
23430515-1	2013	ALG6-CDG (formerly named CDG-Ic) (phenotype OMIM 603147, genotype OMIM 604566), is caused by defective endoplasmic reticulum alpha-1,3-glucosyltransferase (E.C 2.4.1.267) in the N-glycan assembly pathway (Grunewald et al.	n-glycan	178-186	ALG6 alpha-1,3-glucosyltransferase	Homo sapiens	0-4
23225753-0	2013	Effect of ganglioside GM3 synthase gene knockout on the glycoprotein N-glycan profile of mouse embryonic fibroblast.	n-glycan	69-77	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	10-34
23475714-8	2013	The presence of short N-glycan structures is explained by the low level of N-acetylglucosaminyltransferase I (GNT-I) activity and the absence of several other glycosyltransferases, such as GNT-II and beta1,4-galactosyltransferase I (beta1,4GalTI), and of sialyltransferases.In this chapter, we show that the glycosylation pathway of a lepidopteran cell line can be modified via infection with an engineered baculovirus to "humanize" the glycosylation pattern of a recombinant protein.	n-glycan	22-30	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	189-195
23516343-0	2013	Restricted N-glycan conformational space in the PDB and its implication in glycan structure modeling.	n-glycan	11-19	PDB1	Homo sapiens	48-51
23382691-9	2013	As IKZF1 was associated with multiple IgG N-glycan traits, we explored biomarker potential of affected N-glycans in 101 cases with SLE and 183 matched controls and demonstrated substantial discriminative power in a ROC-curve analysis (area under the curve = 0.842).	n-glycan	42-50	IKAROS family zinc finger 1	Homo sapiens	3-8
23001868-0	2013	Serum protein N-glycan alterations of diethylnitrosamine-induced hepatocellular carcinoma mice and their evolution after inhibition of the placental growth factor.	n-glycan	14-22	placental growth factor	Mus musculus	139-162
22855528-8	2012	Endolyn synthesized in the presence of kifunensine, which blocks terminal N-glycan processing, reduced its interaction with several recombinant canine galectins, and knockdown of galectin-9 (but not galectin-3, -4, or -8) selectively disrupted endolyn polarity.	n-glycan	74-82	CD164 molecule	Rattus norvegicus	0-7
23372778-6	2013	A human erythropoietin fusion protein (EPOFc) was transiently expressed in Nicotiana benthamiana DeltaXTFT, a glycosylation mutant that lacks plant specific N-glycan residues.	n-glycan	157-165	erythropoietin	Homo sapiens	8-22
22766194-0	2012	The human CD10 lacking an N-glycan at Asn(628) is deficient in surface expression and neutral endopeptidase activity.	n-glycan	26-34	membrane metalloendopeptidase	Homo sapiens	10-14
22766194-0	2012	The human CD10 lacking an N-glycan at Asn(628) is deficient in surface expression and neutral endopeptidase activity.	n-glycan	26-34	membrane metalloendopeptidase	Homo sapiens	86-107
22766194-8	2012	Surface expression of N-glycan at Asn(628)-deleted CD10 by HEK293 cells was greatly decreased as well as it lost entire NEP activities.	n-glycan	22-30	membrane metalloendopeptidase	Homo sapiens	51-55
22766194-8	2012	Surface expression of N-glycan at Asn(628)-deleted CD10 by HEK293 cells was greatly decreased as well as it lost entire NEP activities.	n-glycan	22-30	membrane metalloendopeptidase	Homo sapiens	120-123
22915798-5	2012	S-pseudovirus produced by calnexin siRNA-treated cells contained S protein modified with N-glycan side chains differently from other two S proteins and consisted of two kinds of viral particles: those of normal density with little S protein and those of high density with abundant S protein.	n-glycan	89-97	calnexin	Homo sapiens	26-34
22930475-9	2012	However, analysis of transferrin N-glycan structures showed an increase in terminal galactose residues in older men, suggesting that the loss of terminal N-acetyl neuraminic acid residues contributes to the more acid pI of transferrin spots observed with age.	n-glycan	33-41	transferrin	Homo sapiens	21-32
22908222-6	2012	In contrast, N-glycan addition is essential for the synaptic localization and function of synaptophysin.	n-glycan	13-21	synaptophysin	Mus musculus	90-103
22954207-0	2012	Solving the convergence problem in the synthesis of triantennary N-glycan relevant to prostate-specific membrane antigen (PSMA).	n-glycan	65-73	folate hydrolase 1	Homo sapiens	86-120
22954207-0	2012	Solving the convergence problem in the synthesis of triantennary N-glycan relevant to prostate-specific membrane antigen (PSMA).	n-glycan	65-73	folate hydrolase 1	Homo sapiens	122-126
23050552-8	2012	The previously reported N-glycan attachment sites of human fibrinogen could be confirmed.	n-glycan	24-32	fibrinogen beta chain	Homo sapiens	59-69
23001782-10	2012	Interestingly, the size and charge heterogeneity were shown to originate predominantly from differential Asn(351)  glycan occupancies and N-glycan sialylation that may modulate the hSHBG activity.	n-glycan	138-146	sex hormone binding globulin	Homo sapiens	181-186
22849435-4	2012	The present paper reports analyses of the human plasma vWF N-glycan population using advanced MS. Glycomics analyses revealed approximately 100 distinct N-glycan compositions and identified a variety of structural features, including lactosaminic extensions, ABH antigens and sulfated antennae, as well as bisecting and terminal GlcNAc residues.	n-glycan	59-67	von Willebrand factor	Homo sapiens	55-58
22849435-4	2012	The present paper reports analyses of the human plasma vWF N-glycan population using advanced MS. Glycomics analyses revealed approximately 100 distinct N-glycan compositions and identified a variety of structural features, including lactosaminic extensions, ABH antigens and sulfated antennae, as well as bisecting and terminal GlcNAc residues.	n-glycan	153-161	von Willebrand factor	Homo sapiens	55-58
22849435-5	2012	We estimate that some 300 N-glycan structures are carried by human vWF.	n-glycan	26-34	von Willebrand factor	Homo sapiens	67-70
22430811-0	2012	Biologically active, magnICON -expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures.	n-glycan	128-136	erythropoietin	Homo sapiens	41-44
22430811-6	2012	Mass spectrometry-based N-glycan analysis confirmed the presence of multi-antennary N-glycans on plant-expressed EPO-Fc.	n-glycan	24-32	erythropoietin	Homo sapiens	113-116
22776203-5	2012	The four major ZP3 isoforms 4-7 (from acidic to basic) were recognized equally with PNA (Galbeta1-3GalNAc), but the isoforms 5-7 were recognized dominantly with WGA ((beta-GlcNAc)n, clustered Sia), PHA-E (bi- and triantennary N-glycan containing Galbeta1-4GlcNAcbeta1-2Manalpha1-6) and RCA I (terminal Galbeta1-4GlcNAc), respectively.	n-glycan	226-234	zona pellucida sperm-binding protein 3	Gallus gallus	15-18
22745127-6	2012	Thus, the nac(1) Gfr mutation produces a previously unrecognized general defect in N-glycan core fucosylation.	n-glycan	83-91	neuronally altered carbohydrate	Drosophila melanogaster	10-13
22740701-3	2012	To understand its oligosaccharide acceptor specificity, we have previously investigated the binding of tri- and pentasaccharides of N-glycan with a GlcNAc at their nonreducing end and found that the extended sugar moiety in these acceptor substrates binds to the crevice present at the acceptor substrate binding site of the beta4Gal-T1 molecule.	n-glycan	132-140	beta-1,4-galactosyltransferase 1	Homo sapiens	325-336
22740701-4	2012	Here we report seven crystal structures of beta4Gal-T1 in complex with an oligosaccharide acceptor with a nonreducing end GlcNAc that has a beta1-6-glycosidic link and that are analogous to either N-glycan or i/I-antigen.	n-glycan	197-205	beta-1,4-galactosyltransferase 1	Homo sapiens	43-54
22723438-6	2012	Increasing surface N-linked mannose by inhibiting N-glycan processing potentiated monocyte adhesion under flow during tumor necrosis factor-alpha stimulation.	n-glycan	50-58	tumor necrosis factor	Homo sapiens	118-145
22569635-7	2012	N-glycan site occupancy of non-antibody glycoproteins such as recombinant human granulocyte macrophage colony-stimulating factor (rhGM-CSF) was also significantly improved, suggesting that LmSTT3D has broad substrate specificity.	n-glycan	0-8	colony stimulating factor 2	Homo sapiens	80-128
22688517-4	2012	The present study was aimed at elucidating the N-glycosylation of recombinant human LOX-1 with regard to N-glycan profile and N-glycosylation sites.	n-glycan	105-113	oxidized low density lipoprotein receptor 1	Homo sapiens	84-89
22688517-9	2012	The findings described herein will shed new light on further research of the structure-function relationships of LOX-1 N-glycan.	n-glycan	119-127	oxidized low density lipoprotein receptor 1	Homo sapiens	113-118
22579717-5	2012	Further analysis of the N-glycan regulation by way of tunicamycin application or PNGase F treatment in K562/ADR cells showed partial inhibition of biosynthesis and increased sensitivity to chemotherapeutic drugs in vitro.	n-glycan	24-32	N-glycanase 1	Homo sapiens	81-87
21459485-0	2012	A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH.	n-glycan	9-17	transferrin	Homo sapiens	27-38
21459485-3	2012	On sodium dodecyl sulfate-polyacrylamide gel electrophoresis, we found two transferrin isoforms: one had a unique N-glycan (Tf-1) whereas the other had N-glycan similar to that of serum transferrin (Tf-2).	n-glycan	114-122	transferrin	Homo sapiens	75-86
21459485-3	2012	On sodium dodecyl sulfate-polyacrylamide gel electrophoresis, we found two transferrin isoforms: one had a unique N-glycan (Tf-1) whereas the other had N-glycan similar to that of serum transferrin (Tf-2).	n-glycan	152-160	transferrin	Homo sapiens	75-86
22607976-6	2012	Moreover, this modification provides an alternative pathway for degradation, which is EDEM3-mediated N-glycan-dependent ERAD, distinct from the major pathway of Herp-mediated N-glycan-independent ERAD.	n-glycan	101-109	ER degradation enhancing alpha-mannosidase like protein 3	Homo sapiens	86-91
22665489-0	2012	Transcriptional regulation of the protocadherin beta cluster during Her-2 protein-induced mammary tumorigenesis results from altered N-glycan branching.	n-glycan	133-141	erb-b2 receptor tyrosine kinase 2	Mus musculus	68-73
22574931-2	2012	The IgG Fc alone becomes potently anti-inflammatory upon addition of alpha2-6-linked N-acetylneuraminic acid residues to the N-glycan, stimulating interest in use of this entity in novel therapies for autoimmune disease [Kaneko et al.	n-glycan	125-133	immunoglobulin binding protein 1	Homo sapiens	69-77
22733738-4	2012	EBS3 encodes the Arabidopsis ortholog of the yeast asparagine-linked glycosylation 9 (ALG9), which catalyzes the ER luminal addition of two terminal alpha1,2 mannose (Man) residues in assembling the three-branched N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).	n-glycan	214-222	Alg9-like mannosyltransferase family	Arabidopsis thaliana	0-4
22733738-4	2012	EBS3 encodes the Arabidopsis ortholog of the yeast asparagine-linked glycosylation 9 (ALG9), which catalyzes the ER luminal addition of two terminal alpha1,2 mannose (Man) residues in assembling the three-branched N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).	n-glycan	214-222	dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase	Saccharomyces cerevisiae S288C	51-84
22733738-4	2012	EBS3 encodes the Arabidopsis ortholog of the yeast asparagine-linked glycosylation 9 (ALG9), which catalyzes the ER luminal addition of two terminal alpha1,2 mannose (Man) residues in assembling the three-branched N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).	n-glycan	214-222	dolichyl-P-Man:Man(6)GlcNAc(2)-PP-dolichol alpha-1,2-mannosyltransferase	Saccharomyces cerevisiae S288C	86-90
22733738-6	2012	By contrast, overexpression of EBS4 in ebs3-1 bri1-9, which encodes the Arabidopsis ortholog of the yeast ALG12 catalyzing the ER luminal alpha1,6 Man addition, adds an alpha1,6 Man to the truncated N-glycan precursor accumulated in ebs3-1 bri1-9, promotes the bri1-9 ERAD, and neutralizes the ebs3-1 suppressor phenotype.	n-glycan	199-207	homolog of asparagine-linked glycosylation 12	Arabidopsis thaliana	31-35
22733738-6	2012	By contrast, overexpression of EBS4 in ebs3-1 bri1-9, which encodes the Arabidopsis ortholog of the yeast ALG12 catalyzing the ER luminal alpha1,6 Man addition, adds an alpha1,6 Man to the truncated N-glycan precursor accumulated in ebs3-1 bri1-9, promotes the bri1-9 ERAD, and neutralizes the ebs3-1 suppressor phenotype.	n-glycan	199-207	Alg9-like mannosyltransferase family	Arabidopsis thaliana	39-43
22733738-7	2012	Furthermore, a transfer (T)-DNA insertional alg3-T2 mutation, which causes accumulation of an even smaller N-glycan precursor carrying a different exposed alpha1,6 Man, promotes the ERAD of bri1-9 and enhances its dwarfism.	n-glycan	107-115	integral membrane protein 2B	Homo sapiens	190-196
22715337-9	2012	The precise identification of the TLR2 N-glycan(s) targeted by ArtinM may support novel basis for the development of antifungal therapy.	n-glycan	39-47	toll-like receptor 2	Mus musculus	34-38
22492969-2	2012	T-synthase (C1GALT1) transfers Gal to generate core 1 and core 2 mucin O-glycans; POFUT1 transfers O-fucose to particular epidermal growth factor-like repeats and is essential for canonical Notch signaling; and MGAT1 (GlcNAcT-I) transfers GlcNAc to initiate hybrid and complex N-glycan synthesis.	n-glycan	277-285	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Homo sapiens	0-10
22492969-2	2012	T-synthase (C1GALT1) transfers Gal to generate core 1 and core 2 mucin O-glycans; POFUT1 transfers O-fucose to particular epidermal growth factor-like repeats and is essential for canonical Notch signaling; and MGAT1 (GlcNAcT-I) transfers GlcNAc to initiate hybrid and complex N-glycan synthesis.	n-glycan	277-285	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Homo sapiens	12-19
22492969-2	2012	T-synthase (C1GALT1) transfers Gal to generate core 1 and core 2 mucin O-glycans; POFUT1 transfers O-fucose to particular epidermal growth factor-like repeats and is essential for canonical Notch signaling; and MGAT1 (GlcNAcT-I) transfers GlcNAc to initiate hybrid and complex N-glycan synthesis.	n-glycan	277-285	protein O-fucosyltransferase 1	Homo sapiens	82-88
22584580-0	2012	Functional regulation of sugar assimilation by N-glycan-specific interaction of pancreatic alpha-amylase with glycoproteins of duodenal brush border membrane.	n-glycan	47-55	amylase alpha 2A	Homo sapiens	80-104
22266356-1	2012	beta-Galactoside alpha2,6-sialyltransferase (ST6Gal-I) has been shown to catalyze alpha2,6 sialylation of N-glycan, an action that is highly correlated with colon cancer progression and metastasis.	n-glycan	106-114	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Homo sapiens	45-53
25284963-0	2012	N-glycan Cryptic Antigens as Active Immunological Targets in Prostate Cancer Patients.	n-glycan	0-8	cripto, FRL-1, cryptic family 1	Homo sapiens	9-16
25284963-11	2012	Thus, human immune systems actively recognize these N-glycan cryptic carbohydrates and produce targeting antibodies.	n-glycan	52-60	cripto, FRL-1, cryptic family 1	Homo sapiens	61-68
22288682-5	2012	Here, we review the multiple regulatory mechanisms controlling N-glycan branching in T cells and autoimmunity, focusing on recent data implicating a critical role for interleukin-2 (IL-2) and IL-7 signaling.	n-glycan	63-71	interleukin 7	Homo sapiens	192-196
22447934-7	2012	A stronger binding of Cne1 to Kre6 was detected when two glucosidases (Cwh41 and Rot2) that remove glucose on N-glycan were functional.	n-glycan	110-118	calnexin	Saccharomyces cerevisiae S288C	22-26
22447934-7	2012	A stronger binding of Cne1 to Kre6 was detected when two glucosidases (Cwh41 and Rot2) that remove glucose on N-glycan were functional.	n-glycan	110-118	beta-glucan synthesis-associated protein KRE6	Saccharomyces cerevisiae S288C	30-34
22447934-7	2012	A stronger binding of Cne1 to Kre6 was detected when two glucosidases (Cwh41 and Rot2) that remove glucose on N-glycan were functional.	n-glycan	110-118	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	71-76
22447934-7	2012	A stronger binding of Cne1 to Kre6 was detected when two glucosidases (Cwh41 and Rot2) that remove glucose on N-glycan were functional.	n-glycan	110-118	glucan 1,3-alpha-glucosidase ROT2	Saccharomyces cerevisiae S288C	81-85
22451656-5	2012	Changes in the N-glycan patterns on alpha3beta1 integrin, one of the target proteins for GnT-III, were also confirmed by lectin blot analysis.	n-glycan	15-23	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	89-96
22238347-7	2012	Sf-GNT-II only transferred N-acetylglucosamine to Man(alpha1-6)[GlcNAc(beta1-2)Man(alpha1-3)]ManGlcNAc(2), demonstrating that it initiates complex N-glycan production, but cannot use Man(3)GlcNAc(2) to produce hybrid or complex structures.	n-glycan	147-155	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	3-9
22434757-5	2012	RESULTS: Peak 1 (NGA2F) is the most significantly elevated N-glycan in paediatric NASH patients with peak 5 (NA2) demonstrating the largest decrease.	n-glycan	59-67	pseudopodium enriched atypical kinase 1	Homo sapiens	9-15
22238347-7	2012	Sf-GNT-II only transferred N-acetylglucosamine to Man(alpha1-6)[GlcNAc(beta1-2)Man(alpha1-3)]ManGlcNAc(2), demonstrating that it initiates complex N-glycan production, but cannot use Man(3)GlcNAc(2) to produce hybrid or complex structures.	n-glycan	147-155	adrenoceptor alpha 1D	Homo sapiens	54-62
22238347-10	2012	Thus, the substrate specificities and physical juxtapositioning of GNT-I, GNT-II, and FDL support the idea that these enzymes function at the N-glycan processing branch point and are major factors determining the net outcome of the insect cell N-glycosylation pathway.	n-glycan	142-150	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	74-80
22238347-10	2012	Thus, the substrate specificities and physical juxtapositioning of GNT-I, GNT-II, and FDL support the idea that these enzymes function at the N-glycan processing branch point and are major factors determining the net outcome of the insect cell N-glycosylation pathway.	n-glycan	142-150	fused lobes	Drosophila melanogaster	86-89
22396165-4	2012	Removal of terminal sialic acids from N-glycan chains of the epithelial Ca(2+) channel TRPV5 and the renal K(+) channel ROMK by secreted Klotho exposes the underlying disaccharide galactose-N-acetylglucosamine, a ligand for galectin-1.	n-glycan	38-46	transient receptor potential cation channel subfamily V member 5	Homo sapiens	87-92
22268729-6	2012	Combining these databases, 29 highly confident glycoproteins that interact with FBXO6 in an N-glycan dependent manner are identified.	n-glycan	92-100	F-box protein 6	Homo sapiens	80-85
22118573-2	2012	We monitored the trafficking route of two secreted proteins with different apical sorting signals: the N-glycan-dependent cargo glycosylated growth hormone (gGH) and Ensol, a soluble version of endolyn whose apical sorting is independent of N-glycans.	n-glycan	103-111	somatotropin	Canis lupus familiaris	141-155
22969905-6	2012	The differentially expressed genes, such as ST3GalI, FUT8, beta3GalT5, MGAT3 and MGAT5, were mainly involved in the synthesis of N-glycan and glycolipids, particularly the sialyl Lewis antigen.	n-glycan	129-137	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	Homo sapiens	44-51
22969905-6	2012	The differentially expressed genes, such as ST3GalI, FUT8, beta3GalT5, MGAT3 and MGAT5, were mainly involved in the synthesis of N-glycan and glycolipids, particularly the sialyl Lewis antigen.	n-glycan	129-137	fucosyltransferase 8	Homo sapiens	53-57
22969905-6	2012	The differentially expressed genes, such as ST3GalI, FUT8, beta3GalT5, MGAT3 and MGAT5, were mainly involved in the synthesis of N-glycan and glycolipids, particularly the sialyl Lewis antigen.	n-glycan	129-137	beta-1,3-galactosyltransferase 5	Homo sapiens	59-69
22969905-6	2012	The differentially expressed genes, such as ST3GalI, FUT8, beta3GalT5, MGAT3 and MGAT5, were mainly involved in the synthesis of N-glycan and glycolipids, particularly the sialyl Lewis antigen.	n-glycan	129-137	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	71-76
22969905-6	2012	The differentially expressed genes, such as ST3GalI, FUT8, beta3GalT5, MGAT3 and MGAT5, were mainly involved in the synthesis of N-glycan and glycolipids, particularly the sialyl Lewis antigen.	n-glycan	129-137	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	81-86
22219371-0	2012	Structural and mechanistic insight into N-glycan processing by endo-alpha-mannosidase.	n-glycan	40-48	mannosidase endo-alpha	Homo sapiens	63-85
22219371-3	2012	One unusual enzyme, endo-alpha-mannosidase, cleaves mannoside linkages internally within an N-linked glycan chain, short circuiting the classical N-glycan biosynthetic pathway.	n-glycan	146-154	mannosidase endo-alpha	Homo sapiens	20-42
22396165-4	2012	Removal of terminal sialic acids from N-glycan chains of the epithelial Ca(2+) channel TRPV5 and the renal K(+) channel ROMK by secreted Klotho exposes the underlying disaccharide galactose-N-acetylglucosamine, a ligand for galectin-1.	n-glycan	38-46	klotho	Homo sapiens	137-143
23300837-0	2012	All-trans-retinoic acid modulates ICAM-1 N-glycan composition by influencing GnT-III levels and inhibits cell adhesion and trans-endothelial migration.	n-glycan	41-49	intercellular adhesion molecule 1	Homo sapiens	34-40
22187327-2	2012	Although we have determined the N-glycan structures of ICAM-5 in a previous report, their function is unknown.	n-glycan	32-40	intercellular adhesion molecule 5, telencephalin	Mus musculus	55-61
23300837-0	2012	All-trans-retinoic acid modulates ICAM-1 N-glycan composition by influencing GnT-III levels and inhibits cell adhesion and trans-endothelial migration.	n-glycan	41-49	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	77-84
23300837-2	2012	In the present study, we show that all-trans-retinoic acid (ATRA) modulates the N-glycan composition of intercellular adhesion molecule-1 (ICAM-1) by manipulating the expression of two N-acetylglucosaminyltransferases, GnT-III and GnT-V, via the ERK signaling pathway.	n-glycan	80-88	intercellular adhesion molecule 1	Homo sapiens	104-137
23300837-2	2012	In the present study, we show that all-trans-retinoic acid (ATRA) modulates the N-glycan composition of intercellular adhesion molecule-1 (ICAM-1) by manipulating the expression of two N-acetylglucosaminyltransferases, GnT-III and GnT-V, via the ERK signaling pathway.	n-glycan	80-88	intercellular adhesion molecule 1	Homo sapiens	139-145
23300837-2	2012	In the present study, we show that all-trans-retinoic acid (ATRA) modulates the N-glycan composition of intercellular adhesion molecule-1 (ICAM-1) by manipulating the expression of two N-acetylglucosaminyltransferases, GnT-III and GnT-V, via the ERK signaling pathway.	n-glycan	80-88	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	219-226
23300837-2	2012	In the present study, we show that all-trans-retinoic acid (ATRA) modulates the N-glycan composition of intercellular adhesion molecule-1 (ICAM-1) by manipulating the expression of two N-acetylglucosaminyltransferases, GnT-III and GnT-V, via the ERK signaling pathway.	n-glycan	80-88	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	231-236
23300837-10	2012	These data indicate that the alteration of ICAM-1 N-glycan composition by ATRA-induced GnT-III activities hindered cell adhesion and cell migration functions simultaneously, pinpointing a unique regulatory role of specific glycosyltransferases in the biological behaviors of tumor cells and a novel function of ATRA in the modulation of ICAM-1 N-glycan composition.	n-glycan	50-58	intercellular adhesion molecule 1	Homo sapiens	43-49
23300837-10	2012	These data indicate that the alteration of ICAM-1 N-glycan composition by ATRA-induced GnT-III activities hindered cell adhesion and cell migration functions simultaneously, pinpointing a unique regulatory role of specific glycosyltransferases in the biological behaviors of tumor cells and a novel function of ATRA in the modulation of ICAM-1 N-glycan composition.	n-glycan	50-58	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	87-94
23300837-10	2012	These data indicate that the alteration of ICAM-1 N-glycan composition by ATRA-induced GnT-III activities hindered cell adhesion and cell migration functions simultaneously, pinpointing a unique regulatory role of specific glycosyltransferases in the biological behaviors of tumor cells and a novel function of ATRA in the modulation of ICAM-1 N-glycan composition.	n-glycan	344-352	intercellular adhesion molecule 1	Homo sapiens	43-49
23300837-10	2012	These data indicate that the alteration of ICAM-1 N-glycan composition by ATRA-induced GnT-III activities hindered cell adhesion and cell migration functions simultaneously, pinpointing a unique regulatory role of specific glycosyltransferases in the biological behaviors of tumor cells and a novel function of ATRA in the modulation of ICAM-1 N-glycan composition.	n-glycan	344-352	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	87-94
22479522-6	2012	Simulations of glycosylated apoD indicated that a second solvent exposed Met at position 49 was shielded by a triantennerary N-glycan attached to Asn45 thereby precluding lipid interactions.	n-glycan	125-133	apolipoprotein D	Homo sapiens	28-32
22916297-5	2012	We sequenced and recombinantly expressed two ~25 kDa polypeptides (BgAChBP1 and BgAChBP2) with a specific active site, N-glycan site and disulfide bridge variation.	n-glycan	119-127	acetylcholine-binding protein-like	Biomphalaria glabrata	67-75
22916297-5	2012	We sequenced and recombinantly expressed two ~25 kDa polypeptides (BgAChBP1 and BgAChBP2) with a specific active site, N-glycan site and disulfide bridge variation.	n-glycan	119-127	acetylcholine-binding protein-like	Biomphalaria glabrata	80-88
22952606-0	2012	CSF N-glycan profiles to investigate biomarkers in brain developmental disorders: application to leukodystrophies related to eIF2B mutations.	n-glycan	4-12	eukaryotic translation initiation factor 2B subunit delta	Homo sapiens	125-130
22952606-6	2012	In CSF, but not in plasma, of eIF2B-mutated patient samples, we found increased relative intensity of bi-antennary structures and decreased tri-antennary/bisecting structures in N-glycan profiles.	n-glycan	178-186	eukaryotic translation initiation factor 2B subunit delta	Homo sapiens	30-35
21979948-2	2011	ERAD-L is N-glycan-dependent and is characterized by ER mannosidase (Mns1p) and ER mannosidase-like protein (Mnl1p), which generate Man(7)GlcNAc(2) (d1) N-glycans with non-reducing alpha1,6-mannosyl residues.	n-glycan	10-18	meiosis specific nuclear structural 1	Homo sapiens	69-74
22396764-4	2012	Using an introduced N-glycan sensor, deglycosylation experiments and glyco-engineered N. benthamiana plants, we show that RD21 passes through the Golgi where it becomes fucosylated.	n-glycan	20-28	Granulin repeat cysteine protease family protein	Arabidopsis thaliana	122-126
22525502-10	2011	OPN from metastasis HCC tissues presented lower level of some specific glycan structures such as a2, 3- sialic acid, bisecting GlcNAc, biantennary, muti-antennary and high mannose type N-glycan structure.	n-glycan	185-193	secreted phosphoprotein 1	Homo sapiens	0-3
21801300-0	2011	Production of recombinant human granulocyte macrophage-colony stimulating factor in rice cell suspension culture with a human-like N-glycan structure.	n-glycan	131-139	colony stimulating factor 2	Homo sapiens	32-80
22102066-2	2011	Earlier methods combined plant-based sample preparations with CE-LIF N-glycan analysis but suffered from background contaminations, often resulting in non-reproducible results.	n-glycan	69-77	LIF interleukin 6 family cytokine	Homo sapiens	65-68
22243251-8	2011	We determined that pig and mouse KLK4 have NA2 and NA2F biantennary N-glycan cores.	n-glycan	68-76	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	Mus musculus	33-37
22011814-1	2011	The fucosyltransferase 8 gene (FUT8) encodes an enzyme that transfers fucose to the innermost N-acetylglucosamine unit of N-glycan chains.	n-glycan	122-130	fucosyltransferase 8	Homo sapiens	4-24
22011814-1	2011	The fucosyltransferase 8 gene (FUT8) encodes an enzyme that transfers fucose to the innermost N-acetylglucosamine unit of N-glycan chains.	n-glycan	122-130	fucosyltransferase 8	Homo sapiens	31-35
22066476-5	2011	All other placental mammals lack one N-glycan in the shed TSHR A-subunit, the primary Graves" disease autoantigen.	n-glycan	37-45	thyroid stimulating hormone receptor	Mus musculus	58-62
21993307-2	2011	In this study, we focus on the two N-glycan mapping approaches that are used in pharmacopoeial monograph to analyse N-glycans released from fifteen preparations of recombinant human erythropoietin supplied by ten Chinese manufacturers.	n-glycan	35-43	erythropoietin	Homo sapiens	182-196
21937449-6	2011	Indeed, inhibiting biosynthesis of the N-glycan precursor using the small molecule tunicamycin or inhibiting its transfer to CD133 by generating N-glycan-deficient CD133 mutants resulted in undetectable cell surface AC133.	n-glycan	145-153	prominin 1	Homo sapiens	164-169
21937449-7	2011	Among the screen hits involved in N-glycosylation were genes involved in complex N-glycan processing, including the poorly characterized MGAT4C, which we demonstrate to be a positive regulator of cell surface AC133 expression.	n-glycan	81-89	MGAT4 family member C	Homo sapiens	137-143
21937449-7	2011	Among the screen hits involved in N-glycosylation were genes involved in complex N-glycan processing, including the poorly characterized MGAT4C, which we demonstrate to be a positive regulator of cell surface AC133 expression.	n-glycan	81-89	prominin 1	Homo sapiens	209-214
21945958-13	2011	These data demonstrate the advantage of combining site-specific N-glycan removal and immune complex formation as a novel vaccine strategy to improve immunogenicity of targeted Ab epitopes on critical regions of HIV-1 gp120.	n-glycan	64-72	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	217-222
21937449-6	2011	Indeed, inhibiting biosynthesis of the N-glycan precursor using the small molecule tunicamycin or inhibiting its transfer to CD133 by generating N-glycan-deficient CD133 mutants resulted in undetectable cell surface AC133.	n-glycan	145-153	prominin 1	Homo sapiens	125-130
21911496-8	2011	Using rosiglitazone as a model PPARgamma agonist, which decreased TNFalpha-induced high mannose N-glycan expression, we demonstrate a role for these carbohydrate residues in THP-1 rolling and adhesion that is independent of endothelial surface adhesion molecule expression (ICAM-1 and E-selectin).	n-glycan	96-104	peroxisome proliferator activated receptor gamma	Homo sapiens	31-40
21911496-8	2011	Using rosiglitazone as a model PPARgamma agonist, which decreased TNFalpha-induced high mannose N-glycan expression, we demonstrate a role for these carbohydrate residues in THP-1 rolling and adhesion that is independent of endothelial surface adhesion molecule expression (ICAM-1 and E-selectin).	n-glycan	96-104	tumor necrosis factor	Homo sapiens	66-74
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	n-glycan	10-18	mannosidase alpha class 1A member 2	Homo sapiens	73-79
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	n-glycan	10-18	mannosidase alpha class 1C member 1	Homo sapiens	84-90
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	n-glycan	10-18	tumor necrosis factor	Homo sapiens	126-134
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	n-glycan	226-234	mannosidase alpha class 1A member 2	Homo sapiens	73-79
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	n-glycan	226-234	mannosidase alpha class 1C member 1	Homo sapiens	84-90
21911496-9	2011	Data from N-glycan processing gene arrays identified alpha-mannosidases (MAN1A2 and MAN1C1) as targets for down-regulation by TNFalpha, which was reversed by rosiglitazone, a result consistent with altered high mannose/hybrid N-glycan epitopes.	n-glycan	226-234	tumor necrosis factor	Homo sapiens	126-134
21767537-2	2011	To elucidate the role of N-glycans on malaria parasite infection, we induced experimental murine malaria infection (using Plasmodium berghei ANKA) in mice deficient in N-acetylglucosaminyltransferase V (Mgat5), which is one of the enzymes involved in beta1,6-GlcNAc N-glycan biosynthesis.	n-glycan	25-33	mannoside acetylglucosaminyltransferase 5	Mus musculus	168-201
21859949-6	2011	The major N-glycan on CEM cell was the core fucosylated alpha2-6 monosialo-biantennary structure.	n-glycan	10-18	immunoglobulin binding protein 1	Homo sapiens	56-64
21673010-7	2011	For this purpose, rat growth hormone (rGH) with two N-glycan sites (rGH-2N) inserted into the rGH portion (NAS and NFT) was fused to green fluorescent protein (GFP) and expressed in MDCK cells.	n-glycan	52-60	gonadotropin releasing hormone receptor	Rattus norvegicus	22-36
22256424-5	2011	Interestingly, the form of the protein with an endoglycosidase H (endo H)-sensitive N-glycan was the major component of EGFP-tagged and wild-type AE1.	n-glycan	84-92	solute carrier family 4 (anion exchanger), member 1	Mus musculus	146-149
21828250-8	2011	Localization and N-glycan pattern analyses of cargo proteins revealed that AtPRA1.B6-mediated inhibition of anterograde trafficking occurs at the ER.	n-glycan	17-25	prenylated RAB acceptor 1.B6	Arabidopsis thaliana	75-84
21188635-4	2011	Here we show that the alg3-2 mutation reduces the N-glycan heterogeneity on ER resident glycoproteins in seeds.	n-glycan	50-58	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	22-26
21757715-4	2011	The N-glycan contributed to the overall stability of newly synthesized GLUT4.	n-glycan	4-12	solute carrier family 2 member 4	Homo sapiens	71-76
21840710-0	2011	Synthesis and alpha-Glucosidase II inhibitory activity of valienamine pseudodisaccharides relevant to N-glycan biosynthesis.	n-glycan	102-110	sucrase-isomaltase	Homo sapiens	14-31
21840710-2	2011	We synthesised valienamine analogues of the Glc(alpha1 3)Glc and Glc(alpha1 3)Man disaccharides representing the linkages cleaved by alpha-Glucosidase II in N-glycan biosynthesis.	n-glycan	157-165	sucrase-isomaltase	Homo sapiens	133-150
21763115-2	2011	Its mechanism of action is through the inhibition of Golgi alpha-mannosidase II activity in the N-glycan biosynthesis pathway.	n-glycan	96-104	mannosidase 2, alpha 1	Mus musculus	53-79
21757715-7	2011	Interestingly, kifunensine-treated cells also lost sensitivity to insulin, suggesting the functional importance of the N-glycan structure for GLUT4 trafficking.	n-glycan	119-127	insulin	Homo sapiens	66-73
21757715-7	2011	Interestingly, kifunensine-treated cells also lost sensitivity to insulin, suggesting the functional importance of the N-glycan structure for GLUT4 trafficking.	n-glycan	119-127	solute carrier family 2 member 4	Homo sapiens	142-147
21495009-6	2011	The N-glycan pool, released by PNGase F digestion, was characterized using 2D-HPLC, MALDI-TOF mass spectrometry, and by exoglycosidase digestions.	n-glycan	4-12	N-glycanase 1	Homo sapiens	31-37
21613225-5	2011	Surprisingly, mass spectrometric analysis of LIF glycopeptides enriched on the CI-MPR column revealed that all six N-glycan sites could be Man-6-P-modified.	n-glycan	115-123	LIF interleukin 6 family cytokine	Homo sapiens	45-48
21431619-6	2011	Mass spectrometry of tryptic peptides of immunopurified transferrin, however, revealed a novel mutation at the N-glycan attachment site.	n-glycan	111-119	transferrin	Homo sapiens	56-67
21613225-5	2011	Surprisingly, mass spectrometric analysis of LIF glycopeptides enriched on the CI-MPR column revealed that all six N-glycan sites could be Man-6-P-modified.	n-glycan	115-123	insulin like growth factor 2 receptor	Homo sapiens	79-85
20927523-3	2011	In this study, we analyzed whether N-glycan expression is crucial for the loss of E-cadherin-mediated cell-cell adhesion in human colorectal cancer cells.	n-glycan	35-43	cadherin 1	Homo sapiens	82-92
21317243-6	2011	Mass spectrometry-based N-glycan analysis of hEPO and hTF revealed the quantitative formation of bisected (GnGnbi) and tri- as well as tetraantennary complex N-glycans (Gn[GnGn], [GnGn]Gn and [GnGn][GnGn]).	n-glycan	24-32	erythropoietin	Homo sapiens	45-49
21498636-9	2011	The HNF1A region also harbors variants that influence several human traits, including maturity-onset diabetes of the young, type 2 diabetes, low-density lipoprotein cholesterol, and N-glycan levels.	n-glycan	182-190	HNF1 homeobox A	Homo sapiens	4-9
20693405-3	2011	We previously reported a down-regulation of mannose-6-phosphate isomerase (MPI) for core N-glycan production in the CFTR-defective human cell line (IB3).	n-glycan	89-97	mannose phosphate isomerase	Homo sapiens	44-73
20693405-3	2011	We previously reported a down-regulation of mannose-6-phosphate isomerase (MPI) for core N-glycan production in the CFTR-defective human cell line (IB3).	n-glycan	89-97	mannose phosphate isomerase	Homo sapiens	75-78
20693405-3	2011	We previously reported a down-regulation of mannose-6-phosphate isomerase (MPI) for core N-glycan production in the CFTR-defective human cell line (IB3).	n-glycan	89-97	CF transmembrane conductance regulator	Homo sapiens	116-120
21501638-1	2011	Previously, we have shown that simple paucimannosidic N-glycan structures in insect Drosophila S2 cells arise mainly because of beta-N-acetylglucosaminidase (GlcNAcase) action.	n-glycan	54-62	O-GlcNAcase	Drosophila melanogaster	158-167
21501638-3	2011	In the present work, we investigated the synergistic effects of beta-1,4-galactosyltransferase (GalT) expression and GlcNAcase suppression on N-glycan patterns.	n-glycan	142-150	O-GlcNAcase	Drosophila melanogaster	117-126
21573946-2	2011	However, only one N-glycan structure has been reported in recombinant human EC-SOD produced in Chinese hamster ovary (CHO) cells.	n-glycan	18-26	superoxide dismutase 3	Homo sapiens	76-82
21501638-4	2011	We found that the N-glycan pattern of human erythropoietin secreted by engineered S2 cells expressing GalT but not GlcNAcase was complete, even in small portion, except for sialylation; the N-glycan structures had two terminal galactose (Gal) residues.	n-glycan	18-26	erythropoietin	Homo sapiens	44-58
21501638-4	2011	We found that the N-glycan pattern of human erythropoietin secreted by engineered S2 cells expressing GalT but not GlcNAcase was complete, even in small portion, except for sialylation; the N-glycan structures had two terminal galactose (Gal) residues.	n-glycan	18-26	beta-4-galactosyltransferase 7	Drosophila melanogaster	102-106
21501638-4	2011	We found that the N-glycan pattern of human erythropoietin secreted by engineered S2 cells expressing GalT but not GlcNAcase was complete, even in small portion, except for sialylation; the N-glycan structures had two terminal galactose (Gal) residues.	n-glycan	190-198	erythropoietin	Homo sapiens	44-58
21501638-4	2011	We found that the N-glycan pattern of human erythropoietin secreted by engineered S2 cells expressing GalT but not GlcNAcase was complete, even in small portion, except for sialylation; the N-glycan structures had two terminal galactose (Gal) residues.	n-glycan	190-198	beta-4-galactosyltransferase 7	Drosophila melanogaster	102-106
21501638-5	2011	When GalT was expressed but GlcNAcase was not inhibited, N-glycan with GlcNAc and Gal at only one branch end was synthesized.	n-glycan	57-65	beta-4-galactosyltransferase 7	Drosophila melanogaster	5-9
21417406-4	2011	Eight desialylated N-glycan structures of haptoglobin were identified where a bifucosylated triantennary structure was reported for the first time in pancreatic cancer samples.	n-glycan	19-27	haptoglobin	Homo sapiens	42-53
21292995-8	2011	N-glycan analysis of the IgG fraction in both mouse models revealed different changes compared with humans.	n-glycan	0-8	immunoglobulin heavy variable V1-62	Mus musculus	25-28
21573946-3	2011	Thus, a precise N-glycan profile of the recombinant EC-SOD is not available.	n-glycan	16-24	superoxide dismutase 3, extracellular	Mus musculus	52-58
21573946-4	2011	In this study, we report profiling of the N-glycan in the recombinant mouse EC-SOD produced in CHO cells using high-resolution techniques, including the liberation of N-glycans by treatment with PNGase F, fluorescence labeling by pyridylamination, characterization by anion-exchange, normal and reversed phase-HPLC separation, and mass spectrometry.	n-glycan	42-50	superoxide dismutase 3, extracellular	Mus musculus	76-82
21184610-6	2011	Two N-glycan features (LC-7 and LC-8) were identified to be more abundant in plasma of the offspring of long-lived individuals as compared to controls.	n-glycan	4-12	dynein light chain LC8-type 1	Homo sapiens	32-36
21541302-11	2011	It is speculated that physiological changes which lead to a reduction in N-glycan attachment to proteins will alter the functions of the Kv3.1 channel.	n-glycan	73-81	potassium voltage-gated channel subfamily C member 1	Homo sapiens	137-142
21404409-0	2011	Chemical synthesis of a bisphosphorylated mannose-6-phosphate N-glycan and its facile monoconjugation with human carbonic anhydrase II for in vivo fluorescence imaging.	n-glycan	62-70	carbonic anhydrase 2	Homo sapiens	113-134
21252225-3	2011	Total N-glycan analysis of hexo knock-out plants revealed that HEXO1 and HEXO3 contribute equally to the production of paucimannosidic N-glycans in roots, whereas N-glycan processing in leaves depends more heavily on HEXO3 than on HEXO1.	n-glycan	135-143	beta-hexosaminidase 1	Arabidopsis thaliana	63-68
21252225-3	2011	Total N-glycan analysis of hexo knock-out plants revealed that HEXO1 and HEXO3 contribute equally to the production of paucimannosidic N-glycans in roots, whereas N-glycan processing in leaves depends more heavily on HEXO3 than on HEXO1.	n-glycan	135-143	beta-hexosaminidase 3	Arabidopsis thaliana	73-78
20963502-1	2011	beta-1,3-N-acetylglucosaminyltransferase-8(beta3Gn-T8) catalyzes the transfer of GlcNAc to the non-reducing terminus of the Galbeta1-4GlcNAc of tetraantennary N-glycan in vitro.	n-glycan	159-167	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1	Homo sapiens	0-42
20963502-1	2011	beta-1,3-N-acetylglucosaminyltransferase-8(beta3Gn-T8) catalyzes the transfer of GlcNAc to the non-reducing terminus of the Galbeta1-4GlcNAc of tetraantennary N-glycan in vitro.	n-glycan	159-167	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1	Homo sapiens	43-53
21963509-11	2011	However, the recombinant DC2.3a/LEC-12a showed weak affinity for N-glycan E3, which was previously shown to be a preferential endogenous ligand for LEC-6.	n-glycan	65-73	Galectin	Caenorhabditis elegans	148-153
21062743-9	2011	The HRD1 adaptor protein SEL1L had been suggested to play a role in N-glycan-dependent substrate delivery to OS9 and XTP3-B.	n-glycan	68-76	synoviolin 1	Homo sapiens	4-8
21062743-9	2011	The HRD1 adaptor protein SEL1L had been suggested to play a role in N-glycan-dependent substrate delivery to OS9 and XTP3-B.	n-glycan	68-76	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase	Homo sapiens	25-30
21062743-9	2011	The HRD1 adaptor protein SEL1L had been suggested to play a role in N-glycan-dependent substrate delivery to OS9 and XTP3-B.	n-glycan	68-76	OS9 endoplasmic reticulum lectin	Homo sapiens	109-112
21062743-9	2011	The HRD1 adaptor protein SEL1L had been suggested to play a role in N-glycan-dependent substrate delivery to OS9 and XTP3-B.	n-glycan	68-76	endoplasmic reticulum lectin 1	Homo sapiens	117-123
22389815-3	2011	N-glycan branching by Mgat5 regulates interaction of surface glycoproteins with galectins, forming a molecular lattice that differentially controls the concentration of surface glycoproteins.	n-glycan	0-8	mannoside acetylglucosaminyltransferase 5	Mus musculus	22-27
21629267-2	2011	In mice, N-glycan branching by the Golgi enzymes Mgat1 and/or Mgat5 prevents T cell hyperactivity, cytotoxic T-lymphocyte antigen 4 (CTLA-4) endocytosis, spontaneous inflammatory demyelination and neurodegeneration, the latter pathologies characteristic of MS.	n-glycan	9-17	mannoside acetylglucosaminyltransferase 1	Mus musculus	49-54
21030387-4	2011	Two ripening-specific N-glycan processing enzymes, alpha-mannosidase (alpha-Man) and beta-D-N-acetylhexosaminidase (beta-Hex), have been identified and targeted to enhance the shelf life in non-climacteric fruits such as capsicum (Capsicum annuum).	n-glycan	22-30	hematopoietically expressed homeobox	Homo sapiens	121-124
21629267-2	2011	In mice, N-glycan branching by the Golgi enzymes Mgat1 and/or Mgat5 prevents T cell hyperactivity, cytotoxic T-lymphocyte antigen 4 (CTLA-4) endocytosis, spontaneous inflammatory demyelination and neurodegeneration, the latter pathologies characteristic of MS.	n-glycan	9-17	mannoside acetylglucosaminyltransferase 5	Mus musculus	62-67
21629267-2	2011	In mice, N-glycan branching by the Golgi enzymes Mgat1 and/or Mgat5 prevents T cell hyperactivity, cytotoxic T-lymphocyte antigen 4 (CTLA-4) endocytosis, spontaneous inflammatory demyelination and neurodegeneration, the latter pathologies characteristic of MS.	n-glycan	9-17	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	99-131
21629267-2	2011	In mice, N-glycan branching by the Golgi enzymes Mgat1 and/or Mgat5 prevents T cell hyperactivity, cytotoxic T-lymphocyte antigen 4 (CTLA-4) endocytosis, spontaneous inflammatory demyelination and neurodegeneration, the latter pathologies characteristic of MS.	n-glycan	9-17	cytotoxic T-lymphocyte-associated protein 4	Mus musculus	133-139
21203500-3	2010	A novel approach combining genome-wide association and high-throughput glycomics analysis of 2,705 individuals in three population cohorts showed that common variants in the Hepatocyte Nuclear Factor 1alpha (HNF1alpha) and fucosyltransferase genes FUT6 and FUT8 influence N-glycan levels in human plasma.	n-glycan	272-280	HNF1 homeobox A	Homo sapiens	174-217
21886772-8	2011	FKRP contains N-glycan of high mannose and/or hybrid type; however, FKRP N-glycosylation is not required for FKRP homodimer or multimer formation.	n-glycan	14-22	fukutin related protein	Homo sapiens	0-4
22205989-3	2011	Previous studies have shown that the N-glycan(s) and the NH2-terminus affect some blood-related functions of PCI.	n-glycan	37-45	serpin family A member 5	Homo sapiens	109-112
22205989-4	2011	In this study, we have for the first time determined the N-glycan profile of seminal plasma PCI, by mass spectrometry.	n-glycan	57-65	serpin family A member 5	Homo sapiens	92-95
22205989-5	2011	The N-glycan structures differed markedly compared with those of both blood-derived and urinary PCI, providing evidence that the N-glycans of PCI are expressed in a tissue-specific manner.	n-glycan	4-12	serpin family A member 5	Homo sapiens	142-145
22073258-6	2011	Surprisingly, compared with cells expressing wild-type ss4 integrin, an alternation in N-glycan structures expressed on epidermal growth factor receptor (EGFR), and the induction of a stronger association between EGFR and ss4 integrin were observed in DeltaNss4 integrin-expressing cells.	n-glycan	87-95	epidermal growth factor receptor	Homo sapiens	120-152
22073258-6	2011	Surprisingly, compared with cells expressing wild-type ss4 integrin, an alternation in N-glycan structures expressed on epidermal growth factor receptor (EGFR), and the induction of a stronger association between EGFR and ss4 integrin were observed in DeltaNss4 integrin-expressing cells.	n-glycan	87-95	epidermal growth factor receptor	Homo sapiens	154-158
21625599-10	2011	Results herein suggest that individual N-glycan location is critical for the stability, regional folding control and secretion of human tyrosinase and explains some tyrosinase gene missense mutations associated with oculocutaneous albinism type I.	n-glycan	39-47	tyrosinase	Homo sapiens	136-146
21625599-10	2011	Results herein suggest that individual N-glycan location is critical for the stability, regional folding control and secretion of human tyrosinase and explains some tyrosinase gene missense mutations associated with oculocutaneous albinism type I.	n-glycan	39-47	tyrosinase	Homo sapiens	165-175
21553496-6	2011	The plasmid contained ER-ScMnsI-ATMDSI(delta48) was expressed in Pichia pastoris, the Man5GlcNAc2 N-glycan on secreted glycoprotein HSA/GM-CSF was observed.	n-glycan	98-106	colony stimulating factor 2	Homo sapiens	136-142
20803478-3	2011	Among these eight genes, five--ALG3, CAX4, MNS1, OST6 and YBL083C--were associated with N-glycan formation and maturation.	n-glycan	88-96	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	31-35
20803478-3	2011	Among these eight genes, five--ALG3, CAX4, MNS1, OST6 and YBL083C--were associated with N-glycan formation and maturation.	n-glycan	88-96	dolichyldiphosphatase	Saccharomyces cerevisiae S288C	37-41
20803478-3	2011	Among these eight genes, five--ALG3, CAX4, MNS1, OST6 and YBL083C--were associated with N-glycan formation and maturation.	n-glycan	88-96	mannosyl-oligosaccharide 1,2-alpha-mannosidase	Saccharomyces cerevisiae S288C	43-47
20803478-3	2011	Among these eight genes, five--ALG3, CAX4, MNS1, OST6 and YBL083C--were associated with N-glycan formation and maturation.	n-glycan	88-96	dolichyl-diphosphooligosaccharide--protein glycotransferase	Saccharomyces cerevisiae S288C	49-53
21078982-1	2010	The expression of an enzyme, GnT-V, that catalyzes a specific posttranslational modification of a family of glycoproteins, namely a branched N-glycan, is transcriptionally up-regulated during breast carcinoma oncogenesis.	n-glycan	141-149	mannoside acetylglucosaminyltransferase 5	Mus musculus	29-34
21056543-4	2010	It has been reported that PCI isolated from human blood plasma is highly heterogeneous, and that this heterogeneity is caused by differences in N-glycan structures, N-glycosylation occupancy, and the presence of two forms that differ by the presence or absence of 6 amino acids at the amino-terminus.	n-glycan	144-152	serpin family A member 5	Homo sapiens	26-29
20848033-2	2010	Recent structural studies indicate that sperm-associated CD52 antigen carries both a complex type N-glycan and an O-glycan on the polypeptide backbone.	n-glycan	98-106	CD52 molecule	Homo sapiens	57-61
20848033-5	2010	It was found that the endoglycosidase-catalyzed transglycosylation allowed efficient attachment of an intact N-glycan in a single step at the N-glycosylation site, while the recombinant human T-synthase could independently extend the O-linked GalNAc to form the core 1 O-glycan.	n-glycan	109-117	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1	Homo sapiens	192-202
20805222-2	2010	We found that the first fibronectin type III repeat (FN1) of NCAM is required for the polysialylation of N-glycans on the adjacent Ig5 domain, and we proposed that the polysialyltransferases recognize specific sequences in FN1 to position themselves for Ig5 N-glycan polysialylation.	n-glycan	105-113	fibronectin 1	Homo sapiens	53-56
20805222-8	2010	Taken together, our results highlight the role of the FN1 alpha-helix and QVQ sequences in N-glycan polysialylation and demonstrate that the acidic patch primarily functions in O-glycan polysialylation.	n-glycan	91-99	fibronectin 1	Homo sapiens	54-57
20670608-8	2010	This weaker binding may be attributed to interference of the Asn(169)N-glycan with the HCII heparin-binding site.	n-glycan	69-77	serpin family D member 1	Homo sapiens	87-91
20739279-5	2010	Through crystallographic analysis of SynCAM 2, we identified within the adhesive interface of its Ig1 domain an N-glycan on residue Asn(60).	n-glycan	112-120	cell adhesion molecule 2	Homo sapiens	37-45
20805222-2	2010	We found that the first fibronectin type III repeat (FN1) of NCAM is required for the polysialylation of N-glycans on the adjacent Ig5 domain, and we proposed that the polysialyltransferases recognize specific sequences in FN1 to position themselves for Ig5 N-glycan polysialylation.	n-glycan	105-113	neural cell adhesion molecule 1	Homo sapiens	61-65
20805222-2	2010	We found that the first fibronectin type III repeat (FN1) of NCAM is required for the polysialylation of N-glycans on the adjacent Ig5 domain, and we proposed that the polysialyltransferases recognize specific sequences in FN1 to position themselves for Ig5 N-glycan polysialylation.	n-glycan	105-113	fibronectin 1	Homo sapiens	223-226
20805325-6	2010	Therefore, GnT1IP is a regulator of GlcNAcT-I and complex and hybrid N-glycan production.	n-glycan	69-77	MGAT4 family, member C	Mus musculus	11-17
20547376-5	2010	Recombinant BmFDL cleaved only beta-1,2-linked GlcNAc residues from the alpha-1,3 branch of biantennary N-glycan.	n-glycan	104-112	fused lobes	Bombyx mori	12-17
20815339-6	2010	The electrostatic parameter of the IL-7-IL-7Ralpha interaction is not driven by complementary charge interactions through residues at the binding interface or N-glycan composition of IL-7Ralpha, but presumably by favorable global charges of the two proteins.	n-glycan	159-167	interleukin 7	Homo sapiens	35-39
20815339-6	2010	The electrostatic parameter of the IL-7-IL-7Ralpha interaction is not driven by complementary charge interactions through residues at the binding interface or N-glycan composition of IL-7Ralpha, but presumably by favorable global charges of the two proteins.	n-glycan	159-167	interleukin 7 receptor	Homo sapiens	40-50
20542090-9	2010	Mutagenetic analysis revealed that the N-glycan attached to Asn42 was bulky in rMCL.	n-glycan	39-47	C-type lectin domain family 4, member D	Rattus norvegicus	79-83
20542090-10	2010	CONCLUSIONS: The high-mannose-type N-glycan attached in yeast blocks the taste-modifying activity of rMCL.	n-glycan	35-43	C-type lectin domain family 4, member D	Rattus norvegicus	101-105
20542090-11	2010	GENERAL SIGNIFICANCE: The bulky N-glycan attached to Asn42 may cause steric hindrance in the interaction between active residues and the sweet taste receptor hT1R2/hT1R3.	n-glycan	32-40	taste 1 receptor member 2	Homo sapiens	158-163
20542090-11	2010	GENERAL SIGNIFICANCE: The bulky N-glycan attached to Asn42 may cause steric hindrance in the interaction between active residues and the sweet taste receptor hT1R2/hT1R3.	n-glycan	32-40	taste 1 receptor member 3	Homo sapiens	164-169
19826906-1	2010	In plants and animals, the first step in complex type N-glycan formation on glycoproteins is catalyzed by N-acetylglucosaminyltransferase I (GnTI).	n-glycan	54-62	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	141-145
20573953-4	2010	Unexpectedly, the structure reveals that the sites of Ig5 polysialylation are on the opposite face from the FN1 residues previously found to be critical for N-glycan polysialylation, suggesting that the Ig5-FN1 domain relationship may be flexible and/or that there is flexibility in the placement of Ig5 glycosylation sites for polysialylation.	n-glycan	157-165	fibronectin 1	Homo sapiens	108-111
20573953-4	2010	Unexpectedly, the structure reveals that the sites of Ig5 polysialylation are on the opposite face from the FN1 residues previously found to be critical for N-glycan polysialylation, suggesting that the Ig5-FN1 domain relationship may be flexible and/or that there is flexibility in the placement of Ig5 glycosylation sites for polysialylation.	n-glycan	157-165	fibronectin 1	Homo sapiens	207-210
20715853-5	2010	A DNA binding polyacridine peptide, Cys-(Acr-Lys)(4), was prepared by solid-phase peptide synthesis using Fmoc-Lys(Acr), then conjugated to the maleimide on the N-glycan to produce a glycopeptide.	n-glycan	161-169	acrosin	Cricetulus griseus	41-44
20571546-0	2010	Introduction of an N-glycan sequon into HEXA enhances human beta-hexosaminidase cellular uptake in a model of Sandhoff disease.	n-glycan	19-27	hexosaminidase subunit alpha	Homo sapiens	40-44
20571546-0	2010	Introduction of an N-glycan sequon into HEXA enhances human beta-hexosaminidase cellular uptake in a model of Sandhoff disease.	n-glycan	19-27	O-GlcNAcase	Homo sapiens	60-79
20571546-3	2010	The mutant HexA (NgHexA) obtained from a Chinese hamster ovary (CHO) cell line co-expressing the mutated HEXA and wild-type HEXB complementary DNAs was demonstrated to contain an additional mannose-6-phosphate (M6P)-type-N-glycan.	n-glycan	221-229	beta-hexosaminidase subunit alpha	Cricetulus griseus	11-15
20551139-4	2010	Here, we found that CD133 could be sialylated in neural stem cells and glioma-initiating cells, and the sialyl residues attach to CD133 N-glycan terminal via alpha2,3-linkage.	n-glycan	136-144	prominin 1	Homo sapiens	20-25
20551139-4	2010	Here, we found that CD133 could be sialylated in neural stem cells and glioma-initiating cells, and the sialyl residues attach to CD133 N-glycan terminal via alpha2,3-linkage.	n-glycan	136-144	prominin 1	Homo sapiens	130-135
20466647-1	2010	FUT8, a eukaryotic alpha1,6-fucosyltransferase, catalyzes the transfer of a fucosyl residue from guanine nucleotide diphosphate-beta-l-fucose to the innermost GlcNAc of an asparagine-linked oligosaccharide (N-glycan).	n-glycan	207-215	fucosyltransferase 8	Homo sapiens	0-4
20466647-1	2010	FUT8, a eukaryotic alpha1,6-fucosyltransferase, catalyzes the transfer of a fucosyl residue from guanine nucleotide diphosphate-beta-l-fucose to the innermost GlcNAc of an asparagine-linked oligosaccharide (N-glycan).	n-glycan	207-215	fucosyltransferase 8	Homo sapiens	19-46
20726802-7	2010	These N-glycan changes in PCa PSA subforms highlight the importance of glycosylation as an indicator of PCa disease.	n-glycan	6-14	kallikrein related peptidase 3	Homo sapiens	30-33
20405899-14	2010	Comparing the LC-MS/MS results of the tryptic digest of glycoproteins treated with PNGase F and Endo-M/exoglycosidases allowed the assignment of core fucose residues to N-glycan reducing-ends.	n-glycan	169-177	N-glycanase 1	Homo sapiens	83-89
20502833-0	2010	The Glc2Man2-fragment of the N-glycan precursor--a novel ligand for the glycan-binding protein malectin?	n-glycan	29-37	malectin	Homo sapiens	95-103
20494584-0	2010	Probe design and synthesis of Galbeta(1-->3)[NeuAcalpha(2-->6)]GlcNAcbeta(1-->2)Man motif of N-glycan.	n-glycan	102-110	alpha-N-acetylgalactosaminidase	Homo sapiens	30-37
20469932-0	2010	N-glycan analysis of recombinant L-Selectin reveals sulfated GalNAc and GalNAc-GalNAc motifs.	n-glycan	0-8	selectin L	Homo sapiens	33-43
20434428-0	2010	ABH blood group antigens in N-glycan of human glycophorin A.	n-glycan	28-36	alkB homolog 1, histone H2A dioxygenase	Homo sapiens	0-3
20434428-0	2010	ABH blood group antigens in N-glycan of human glycophorin A.	n-glycan	28-36	glycophorin A (MNS blood group)	Homo sapiens	46-59
20434428-4	2010	By the use of immunochemical methods we obtained results indicating that ABH blood group epitopes are also present in N-glycan of human GPA (Podbielska and Krotkiewski (2000) [22]).	n-glycan	118-126	alkB homolog 1, histone H2A dioxygenase	Homo sapiens	73-76
20434428-4	2010	By the use of immunochemical methods we obtained results indicating that ABH blood group epitopes are also present in N-glycan of human GPA (Podbielska and Krotkiewski (2000) [22]).	n-glycan	118-126	glycophorin A (MNS blood group)	Homo sapiens	136-139
20434428-7	2010	The ABH blood group epitopes are present on one antenna of the N-glycan, whereas a known sialylated sequence NeuAcalpha2-6Galbeta1-4GlcNAc- occurs on the other antenna and other details are in agreement with the known major structure of the GPA N-glycan.	n-glycan	63-71	alkB homolog 1, histone H2A dioxygenase	Homo sapiens	4-7
20434428-7	2010	The ABH blood group epitopes are present on one antenna of the N-glycan, whereas a known sialylated sequence NeuAcalpha2-6Galbeta1-4GlcNAc- occurs on the other antenna and other details are in agreement with the known major structure of the GPA N-glycan.	n-glycan	245-253	alkB homolog 1, histone H2A dioxygenase	Homo sapiens	4-7
20398652-0	2010	S-opsin protein is incompletely modified during N-glycan processing in Rpe65(-/-) mice.	n-glycan	48-56	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	Mus musculus	0-7
20398652-7	2010	To examine modification patterns of N-glycan in Rpe65(-/-) mice, cone opsins were digested with peptide-N-glycosidase (PNGase) F. S-opsin protein was detected at approximately 40-kDa as a major band in wild-type mice, whereas approximately 42-kDa S-opsin protein was detected in Rpe65(-/-) mice.	n-glycan	36-44	opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)	Mus musculus	130-137
20494584-1	2010	Synthesis and clusterization of Galbeta(1-->3)[NeuAcalpha(2-->6)]GlcNAcbeta(1-->2)Man motif of the N-glycan, as the molecular probes for their biological evaluation, are reported.	n-glycan	108-116	alpha-N-acetylgalactosaminidase	Homo sapiens	32-39
20398363-2	2010	ALG6-CDG (CDGIc) is an endoplasmatic reticulum defect in N-glycan assembly.	n-glycan	57-65	ALG6 alpha-1,3-glucosyltransferase	Homo sapiens	0-4
20356820-7	2010	N-Glycan profiling of total proteins from alg3 mutants exhibited a unique structural profile, alg3 has rare N-glycan structures including Man(3)GlcNAc(2), M4(ER), M5(ER) and GlcM5(ER), which are not usually detected in Arabidopsis, and a much less amount of complex-type N-glycan than that in wild type.	n-glycan	0-8	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	94-98
20356820-7	2010	N-Glycan profiling of total proteins from alg3 mutants exhibited a unique structural profile, alg3 has rare N-glycan structures including Man(3)GlcNAc(2), M4(ER), M5(ER) and GlcM5(ER), which are not usually detected in Arabidopsis, and a much less amount of complex-type N-glycan than that in wild type.	n-glycan	108-116	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	94-98
20356820-7	2010	N-Glycan profiling of total proteins from alg3 mutants exhibited a unique structural profile, alg3 has rare N-glycan structures including Man(3)GlcNAc(2), M4(ER), M5(ER) and GlcM5(ER), which are not usually detected in Arabidopsis, and a much less amount of complex-type N-glycan than that in wild type.	n-glycan	271-279	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	94-98
20332087-3	2010	Here, the N-glycan composition of native dimeric human MPO purified from neutrophils and of monomeric MPO recombinantly expressed in Chinese hamster ovary cells has been investigated.	n-glycan	10-18	myeloperoxidase	Homo sapiens	55-58
20348404-0	2010	Diagnostic value of the hemopexin N-glycan profile in hepatocellular carcinoma patients.	n-glycan	34-42	hemopexin	Homo sapiens	24-33
20348404-7	2010	The hemopexin N-glycan profile was determined by use of the DNA sequencer-assisted fluorophore-assisted carbohydrate electrophoresis technique.	n-glycan	14-22	hemopexin	Homo sapiens	4-13
20431350-0	2010	Differences in N-glycan structures found on recombinant IgA1 and IgA2 produced in murine myeloma and CHO cell lines.	n-glycan	15-23	immunoglobulin heavy constant alpha 1	Homo sapiens	56-60
20150426-7	2010	N-Glycan structures on misfolded glycoproteins in cells lacking the cytosol/vacuole alpha-mannosidase, Ams1p, was still quite diverse, indicating that processing of N-glycans on misfolded glycoproteins was more complex than currently envisaged.	n-glycan	0-8	alpha-mannosidase	Saccharomyces cerevisiae S288C	84-101
20150426-7	2010	N-Glycan structures on misfolded glycoproteins in cells lacking the cytosol/vacuole alpha-mannosidase, Ams1p, was still quite diverse, indicating that processing of N-glycans on misfolded glycoproteins was more complex than currently envisaged.	n-glycan	0-8	alpha-mannosidase	Saccharomyces cerevisiae S288C	103-108
20118070-8	2010	Moreover, recent studies have identified the N-glycan species with which both yeast Yos9p and mammalian OS-9 associate as M7A, a Man(7)GlcNAc(2) isomer that lacks the alpha1,2-linked terminal mannose from both the B and C branches.	n-glycan	45-53	Yos9p	Saccharomyces cerevisiae S288C	84-89
20118070-8	2010	Moreover, recent studies have identified the N-glycan species with which both yeast Yos9p and mammalian OS-9 associate as M7A, a Man(7)GlcNAc(2) isomer that lacks the alpha1,2-linked terminal mannose from both the B and C branches.	n-glycan	45-53	OS9 endoplasmic reticulum lectin	Homo sapiens	104-108
20335257-10	2010	Collectively, our data show that the antennae of complex N-glycans serve to protect the V3 loop and CD4 binding site, while N-glycan stems regulate native trimer conformation, such that their removal can lead to global changes in neutralization sensitivity and, in extreme cases, an inability to complete the conformational rearrangements necessary for infection.	n-glycan	57-65	CD4 molecule	Homo sapiens	100-103
19914916-7	2010	Arabidopsis mutant lines manIa-1, manIa-2, manIb-1, and manIb-2 showed N-glycan profiles similar to that of wild type.	n-glycan	71-79	alpha-mannosidase 2	Arabidopsis thaliana	25-30
20199105-5	2010	Furthermore, the fully N-glycosylated beta(2) subunit is retained in the ER when glycan-calnexin interactions are prevented by castanospermine, showing that N-glycan-mediated calnexin binding is required for correct subunit folding.	n-glycan	157-165	calnexin	Canis lupus familiaris	88-96
20199105-5	2010	Furthermore, the fully N-glycosylated beta(2) subunit is retained in the ER when glycan-calnexin interactions are prevented by castanospermine, showing that N-glycan-mediated calnexin binding is required for correct subunit folding.	n-glycan	157-165	calnexin	Canis lupus familiaris	175-183
21137062-5	2010	An increase in N-glycan branching was detected on AGP and HPT in the advanced stage of PaC and CP and on FET and TRF in the CP.	n-glycan	15-23	transferrin	Homo sapiens	113-116
20080937-3	2010	The isoelectric focusing pattern of the patient"s serum transferrin showed the partial loss of complete N-glycan side chains, which is a characteristic sign for CDG-I.	n-glycan	104-112	transferrin	Homo sapiens	56-67
19914916-7	2010	Arabidopsis mutant lines manIa-1, manIa-2, manIb-1, and manIb-2 showed N-glycan profiles similar to that of wild type.	n-glycan	71-79	alpha-mannosidase 2	Arabidopsis thaliana	34-39
19914916-8	2010	On the other hand, the manIa manIb double mutant lines produced Man(8)GlcNAc(2) as the predominant N-glycan and lacked plant-specific complex and hybrid N-glycans.	n-glycan	99-107	alpha-mannosidase 2	Arabidopsis thaliana	23-28
19914916-9	2010	These data indicate that either AtMANIa or AtMANIb can function as the Golgi alpha-mannosidase I that produces the Man(5)GlcNAc(2) N-glycan structure necessary for complex N-glycan synthesis.	n-glycan	131-139	alpha-mannosidase 2	Arabidopsis thaliana	32-39
19914916-9	2010	These data indicate that either AtMANIa or AtMANIb can function as the Golgi alpha-mannosidase I that produces the Man(5)GlcNAc(2) N-glycan structure necessary for complex N-glycan synthesis.	n-glycan	172-180	alpha-mannosidase 2	Arabidopsis thaliana	32-39
19920154-3	2010	Here we show that galectin-1 signaling through CD45, which carries both N- and O-glycans, is regulated by CD45 isoform expression, core 2 O-glycan formation and the balance of N-glycan sialylation.	n-glycan	176-184	galectin 1	Homo sapiens	18-28
19819901-6	2010	The recombinant tomato PNGase showed optimum activity at pH 4.5 and 40 degrees C. It did not require any metal ions for full enzymatic activity and could release the complex-type N-glycan from glycopeptides.	n-glycan	179-187	peptide N-glycanase	Solanum lycopersicum	23-29
19920154-3	2010	Here we show that galectin-1 signaling through CD45, which carries both N- and O-glycans, is regulated by CD45 isoform expression, core 2 O-glycan formation and the balance of N-glycan sialylation.	n-glycan	176-184	protein tyrosine phosphatase receptor type C	Homo sapiens	47-51
20139591-0	2010	The multiplicity of N-glycan structures of bovine milk 18 kda lactophorin (milk GlyCAM-1).	n-glycan	20-28	glycosylation dependent cell adhesion molecule 1	Bos taurus	62-73
21140004-7	2010	Our data showed that blocking of N-glycan transfer to the nascent polypeptide chain with the antibiotic tunicamycin resulted in the loss of E1 and E2.	n-glycan	33-41	small nucleolar RNA, H/ACA box 73A	Homo sapiens	140-149
19931508-0	2010	Definitive evidence that a single N-glycan among three glycans on inducible costimulator is required for proper protein trafficking and ligand binding.	n-glycan	34-42	inducible T cell costimulator	Homo sapiens	66-88
19931508-4	2010	Here we demonstrate the integral involvement of a specific N-glycan from amongst the three glycans present on inducible costimulator (ICOS), a T-cell costimulatory molecule, in proper protein folding and intracellular trafficking to the cell surface membrane.	n-glycan	59-67	inducible T cell costimulator	Homo sapiens	110-132
19931508-4	2010	Here we demonstrate the integral involvement of a specific N-glycan from amongst the three glycans present on inducible costimulator (ICOS), a T-cell costimulatory molecule, in proper protein folding and intracellular trafficking to the cell surface membrane.	n-glycan	59-67	inducible T cell costimulator	Homo sapiens	134-138
20944405-1	2010	We have recently demonstrated that the 1CF11 monoclonal antibody bound human milk lactoferrin (hLf) through the recognition of two distinct portions of the molecule, namely the N-glycan-relevant and -irrelevant structural elements.	n-glycan	177-185	HLF transcription factor, PAR bZIP family member	Homo sapiens	95-98
20944405-3	2010	Deglycosylation of these fractions and a competitive binding assay using fucosylated oligosaccharides revealed that the non-reducing terminal fucose residue in N-linked glycan(s) played a significant role in recognizing the N-glycan-relevant element in hLf by 1CF11.	n-glycan	224-232	HLF transcription factor, PAR bZIP family member	Homo sapiens	253-256
20944410-3	2010	We reveal by treating hLF with trypsin and/or N-glycosidase that both the N-glycan-relevant and N-glycan-irrelevant structural elements were involved in the recognition of hLf by 1CF11.	n-glycan	74-82	HLF transcription factor, PAR bZIP family member	Homo sapiens	22-25
20944410-3	2010	We reveal by treating hLF with trypsin and/or N-glycosidase that both the N-glycan-relevant and N-glycan-irrelevant structural elements were involved in the recognition of hLf by 1CF11.	n-glycan	74-82	HLF transcription factor, PAR bZIP family member	Homo sapiens	172-175
20944410-3	2010	We reveal by treating hLF with trypsin and/or N-glycosidase that both the N-glycan-relevant and N-glycan-irrelevant structural elements were involved in the recognition of hLf by 1CF11.	n-glycan	96-104	HLF transcription factor, PAR bZIP family member	Homo sapiens	22-25
20944410-3	2010	We reveal by treating hLF with trypsin and/or N-glycosidase that both the N-glycan-relevant and N-glycan-irrelevant structural elements were involved in the recognition of hLf by 1CF11.	n-glycan	96-104	HLF transcription factor, PAR bZIP family member	Homo sapiens	172-175
20139591-0	2010	The multiplicity of N-glycan structures of bovine milk 18 kda lactophorin (milk GlyCAM-1).	n-glycan	20-28	glycosylation dependent cell adhesion molecule 1	Bos taurus	80-88
20062796-0	2010	Caenorhabditis elegans N-glycan core beta-galactoside confers sensitivity towards nematotoxic fungal galectin CGL2.	n-glycan	23-31	Galectin	Caenorhabditis elegans	101-109
20015870-1	2010	N-Acetylglucosaminyltransferase-IV (GnT-IV) has two isoenzymes, GnT-IVa and GnT-IVb, which initiate the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity and conferring endogenous lectin binding epitopes.	n-glycan	165-173	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	64-71
20015870-1	2010	N-Acetylglucosaminyltransferase-IV (GnT-IV) has two isoenzymes, GnT-IVa and GnT-IVb, which initiate the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity and conferring endogenous lectin binding epitopes.	n-glycan	165-173	mannoside acetylglucosaminyltransferase 4, isoenzyme B	Mus musculus	76-83
20816168-3	2010	N-Acetylglucosaminyltransferase-IVa (GnT-IVa) initiates the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity.	n-glycan	121-129	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	0-35
20816168-3	2010	N-Acetylglucosaminyltransferase-IVa (GnT-IVa) initiates the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity.	n-glycan	121-129	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	37-44
20816168-3	2010	N-Acetylglucosaminyltransferase-IVa (GnT-IVa) initiates the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity.	n-glycan	154-162	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	0-35
20816168-3	2010	N-Acetylglucosaminyltransferase-IVa (GnT-IVa) initiates the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity.	n-glycan	154-162	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	37-44
19882694-2	2010	A key reason for this difference is the presence of a highly specific N-glycan processing beta-N-acetylglucosaminidase in insect, but not in mammalian systems.	n-glycan	70-78	O-GlcNAcase	Homo sapiens	90-118
20015870-1	2010	N-Acetylglucosaminyltransferase-IV (GnT-IV) has two isoenzymes, GnT-IVa and GnT-IVb, which initiate the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity and conferring endogenous lectin binding epitopes.	n-glycan	198-206	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	64-71
20015870-1	2010	N-Acetylglucosaminyltransferase-IV (GnT-IV) has two isoenzymes, GnT-IVa and GnT-IVb, which initiate the GlcNAcbeta1-4 branch synthesis on the Manalpha1-3 arm of the N-glycan core thereby increasing N-glycan branch complexity and conferring endogenous lectin binding epitopes.	n-glycan	198-206	mannoside acetylglucosaminyltransferase 4, isoenzyme B	Mus musculus	76-83
20816221-3	2010	GnT-III is generally regarded as a key glycosyltransferase in N-glycan biosynthetic pathways.	n-glycan	62-70	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-7
19732381-3	2009	Here we characterize a new Arabidopsis thaliana mutant lew3 (leaf wilting 3), which has a defect in an alpha-1,2-mannosyltransferase, a homolog of ALG11 in yeast, that transfers mannose to the dolichol-linked core oligosaccharide in the last two steps on the cytosolic face of the ER in N-glycan precursor synthesis.	n-glycan	287-295	UDP-Glycosyltransferase superfamily protein	Arabidopsis thaliana	55-59
19846557-6	2009	A detailed study using site-directed mutagenesis demonstrated that three of the eight putative N-glycosylation sites in the N-cadherin sequence showed N-glycan expression.	n-glycan	151-159	cadherin 2	Homo sapiens	124-134
19733219-2	2009	Here, we determined the N-glycan structure of ICAM-5 purified from adult rat brain and compared it with that of other ICAMs.	n-glycan	24-32	intercellular adhesion molecule 5	Rattus norvegicus	46-52
19733219-6	2009	Compared with the N-glycan structures of human ICAM-1 expressed in CHO cells, HEK cells, or mouse myeloma cells and ICAM-3 isolated from human T-cells, rat brain ICAM-5 had less highly branched glycans, sialylated glycans, and N-acetyllactosamine structures.	n-glycan	18-26	intercellular adhesion molecule 1	Homo sapiens	47-53
19706602-6	2009	Together, these data suggest that TCR signaling differentially regulates multiple N-glycan-processing enzymes at the mRNA level to cooperatively promote beta1,6GlcNAc branching, and by extension, CTLA-4 surface expression, T cell growth arrest, and self-tolerance.	n-glycan	82-90	cytotoxic T-lymphocyte associated protein 4	Homo sapiens	196-202
19852465-0	2009	Functional neoglycopeptides: synthesis and characterization of a new class of MUC1 glycoprotein models having core 2-based O-glycan and complex-type N-glycan chains.	n-glycan	149-157	mucin 1, cell surface associated	Homo sapiens	78-82
19852465-1	2009	An efficient protocol for the construction of MUC1-related glycopeptide analogues having complex O-glycan and N-glycan chains was established by integrating chemical and enzymatic approaches on the functional polymer platforms.	n-glycan	110-118	mucin 1, cell surface associated	Homo sapiens	46-50
19782108-7	2009	Taken together, these results indicated that N-glycan of CSFV E(rns) is essential for E(rns) blocking of IFN-beta induction.	n-glycan	45-53	interferon beta 1	Homo sapiens	105-113
19706602-2	2009	N-Acetylglucosaminyltransferase V (MGAT5) mediates beta1,6GlcNAc-branching by transferring N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to N-glycan substrates produced by the sequential action of Golgi alpha1,2-mannosidase I (MIa,b,c), MGAT1, alpha1,2-mannosidase II (MII, IIx), and MGAT2.	n-glycan	139-147	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-33
19706602-2	2009	N-Acetylglucosaminyltransferase V (MGAT5) mediates beta1,6GlcNAc-branching by transferring N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to N-glycan substrates produced by the sequential action of Golgi alpha1,2-mannosidase I (MIa,b,c), MGAT1, alpha1,2-mannosidase II (MII, IIx), and MGAT2.	n-glycan	139-147	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-40
19706602-2	2009	N-Acetylglucosaminyltransferase V (MGAT5) mediates beta1,6GlcNAc-branching by transferring N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to N-glycan substrates produced by the sequential action of Golgi alpha1,2-mannosidase I (MIa,b,c), MGAT1, alpha1,2-mannosidase II (MII, IIx), and MGAT2.	n-glycan	139-147	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	236-241
19418565-9	2009	For the recombinant enzyme (GP2), it was discovered that culture pH and the timing of butyrate addition can be used to control N-glycan site-occupancy within a specific range.	n-glycan	127-135	pancreatic secretory granule membrane major glycoprotein GP2	Cricetulus griseus	28-31
19706602-2	2009	N-Acetylglucosaminyltransferase V (MGAT5) mediates beta1,6GlcNAc-branching by transferring N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to N-glycan substrates produced by the sequential action of Golgi alpha1,2-mannosidase I (MIa,b,c), MGAT1, alpha1,2-mannosidase II (MII, IIx), and MGAT2.	n-glycan	139-147	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	283-288
19508951-4	2009	Among the glycosyltransferases involved in the biosynthesis of N-glycan branching, this review will focus on the function of Fut8 and N-acetylglucosaminyltransferase III, which directly modify the N-glycan core.	n-glycan	63-71	fucosyltransferase 8	Homo sapiens	125-129
19508951-4	2009	Among the glycosyltransferases involved in the biosynthesis of N-glycan branching, this review will focus on the function of Fut8 and N-acetylglucosaminyltransferase III, which directly modify the N-glycan core.	n-glycan	63-71	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	134-169
19508951-4	2009	Among the glycosyltransferases involved in the biosynthesis of N-glycan branching, this review will focus on the function of Fut8 and N-acetylglucosaminyltransferase III, which directly modify the N-glycan core.	n-glycan	197-205	fucosyltransferase 8	Homo sapiens	125-129
19508951-4	2009	Among the glycosyltransferases involved in the biosynthesis of N-glycan branching, this review will focus on the function of Fut8 and N-acetylglucosaminyltransferase III, which directly modify the N-glycan core.	n-glycan	197-205	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	134-169
19540883-3	2009	The N-glycan structure of beta3GnT2 was identified by glycoamidase A digestion, labeling with 2-aminopyridine (PA), and HPLC mapping.	n-glycan	4-12	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	26-35
19540883-5	2009	In contrast, N-glycan with Gal (21.3%) and GlcNAc (16.2%) terminal residues linked to Manalpha(1,3) branch were detected on beta3GnT2 expressed in silkworm larvae.	n-glycan	13-21	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	124-133
19556306-2	2009	The purposes of this study were to characterize the N-glycan of TLR4 and to investigate the roles of MD-2 in N-linked glycosylation and cell surface expression of TLR4.	n-glycan	52-60	toll like receptor 4	Homo sapiens	64-68
19556306-4	2009	The cells transfected with a mutant TLR4(C88A) alone expressed only the 110 kDa TLR4 with a high mannose type N-glycan, which did not appear on the cell surface.	n-glycan	110-118	toll like receptor 4	Homo sapiens	36-40
19349416-6	2009	Here, we report that KLe treatment increases the cell-membrane abundance of the renal K(+) channel renal outer medullary potassium channel 1 (ROMK1) by removing terminal sialic acids from N-glycan of the channel.	n-glycan	188-196	potassium voltage-gated channel subfamily A member 5	Homo sapiens	121-140
19478090-3	2009	Here we report on the generation of a plant-based expression platform allowing the efficient production of mAbs with a homogeneous beta1,4-galactosylated N-glycosylation structure, the major N-glycan species present on serum IgG.	n-glycan	191-199	DEAD box helicase 41	Mus musculus	107-111
19478090-6	2009	These findings indicate that mAbs containing such homogeneous N-glycan structures should display improved in vivo activities.	n-glycan	62-70	DEAD box helicase 41	Mus musculus	29-33
19451655-3	2009	(GFP)PrP expressed with the wild-type sequence was transported normally through the secretory pathway to the cell surface with acquisition of N-glycan groups, but two N-terminal fragments of (GFP)PrP were detected intracellularly, starting in frame from Met(17).	n-glycan	142-150	major prion protein	Ovis aries	5-8
19594640-8	2009	N-glycan branching is conditional to the activity of Golgi N-acetylglucosaminyl transferases I, II, IV and V (Mgat1, 2, 4, and 5) and metabolic supply of their donor substrate UDP-GlcNAc.	n-glycan	0-8	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	110-128
19377061-6	2009	An unexpected increase in the exposure of alpha-linked mannose also was observed on MUC1 and MUC5ac, indicating possible N-glycan modifications.	n-glycan	121-129	mucin 1, cell surface associated	Homo sapiens	84-88
19377061-6	2009	An unexpected increase in the exposure of alpha-linked mannose also was observed on MUC1 and MUC5ac, indicating possible N-glycan modifications.	n-glycan	121-129	mucin 5AC, oligomeric mucus/gel-forming	Homo sapiens	93-99
19349416-6	2009	Here, we report that KLe treatment increases the cell-membrane abundance of the renal K(+) channel renal outer medullary potassium channel 1 (ROMK1) by removing terminal sialic acids from N-glycan of the channel.	n-glycan	188-196	potassium inwardly rectifying channel subfamily J member 1	Homo sapiens	142-147
19346256-8	2009	The ability of hOS-9 to enhance glycoprotein ERAD depended on the N-glycan structures on NHK, consistent with the frontal affinity chromatography results.	n-glycan	66-74	OS9 endoplasmic reticulum lectin	Homo sapiens	15-20
19500344-8	2009	The purified ST6Gal1 was characterized and its N-glycan patterns were found to be approximately paucimannosidic type by HPLC mapping method.	n-glycan	47-55	ST6 beta-galactoside alpha-2,6-sialyltransferase 1	Rattus norvegicus	13-20
18937645-4	2009	Metabolic labelling of the carbohydrates combined with glycosidase digestion reactions were utilized to show that the N-glycan of recombinant Kv3.1 protein was capped with an oligo/poly-sialyl unit.	n-glycan	118-126	potassium voltage-gated channel subfamily C member 1	Homo sapiens	142-147
19240271-1	2009	The mammalian ER/cytosolic alpha-mannosidase (Man2C1p), yeast vacuolar alpha-mannosidase (Ams1p) and the Aspergillus nidulans alpha-mannosidase are members of Class IIC subgroup, which is involved in oligosaccharide catabolism and N-glycan processing.	n-glycan	231-239	alpha-mannosidase	Saccharomyces cerevisiae S288C	71-88
19236842-3	2009	The overexpression of GnT-V gene in human hepatoma SMMC-7721 cell line not only induced the addition of beta1,6 GlcNAc branch to N-glycan of RPTPkappa but also decreased the protein level of RPTPkappa, which both contributed to the decreased phosphatase activity of RPTPkappa activating subsequently EGFR signaling.	n-glycan	129-137	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	22-27
19236842-3	2009	The overexpression of GnT-V gene in human hepatoma SMMC-7721 cell line not only induced the addition of beta1,6 GlcNAc branch to N-glycan of RPTPkappa but also decreased the protein level of RPTPkappa, which both contributed to the decreased phosphatase activity of RPTPkappa activating subsequently EGFR signaling.	n-glycan	129-137	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	104-111
19236842-3	2009	The overexpression of GnT-V gene in human hepatoma SMMC-7721 cell line not only induced the addition of beta1,6 GlcNAc branch to N-glycan of RPTPkappa but also decreased the protein level of RPTPkappa, which both contributed to the decreased phosphatase activity of RPTPkappa activating subsequently EGFR signaling.	n-glycan	129-137	protein tyrosine phosphatase receptor type K	Homo sapiens	141-150
19240271-1	2009	The mammalian ER/cytosolic alpha-mannosidase (Man2C1p), yeast vacuolar alpha-mannosidase (Ams1p) and the Aspergillus nidulans alpha-mannosidase are members of Class IIC subgroup, which is involved in oligosaccharide catabolism and N-glycan processing.	n-glycan	231-239	alpha-mannosidase	Saccharomyces cerevisiae S288C	27-44
19240271-1	2009	The mammalian ER/cytosolic alpha-mannosidase (Man2C1p), yeast vacuolar alpha-mannosidase (Ams1p) and the Aspergillus nidulans alpha-mannosidase are members of Class IIC subgroup, which is involved in oligosaccharide catabolism and N-glycan processing.	n-glycan	231-239	mannosidase alpha class 2C member 1	Homo sapiens	46-53
19240271-1	2009	The mammalian ER/cytosolic alpha-mannosidase (Man2C1p), yeast vacuolar alpha-mannosidase (Ams1p) and the Aspergillus nidulans alpha-mannosidase are members of Class IIC subgroup, which is involved in oligosaccharide catabolism and N-glycan processing.	n-glycan	231-239	alpha-mannosidase	Saccharomyces cerevisiae S288C	71-88
19714866-9	2009	The loss of catalytic activity caused by the deletion of the second N-glycan was rescued by increasing PPCA expression.	n-glycan	68-76	cathepsin A	Homo sapiens	103-107
19240271-1	2009	The mammalian ER/cytosolic alpha-mannosidase (Man2C1p), yeast vacuolar alpha-mannosidase (Ams1p) and the Aspergillus nidulans alpha-mannosidase are members of Class IIC subgroup, which is involved in oligosaccharide catabolism and N-glycan processing.	n-glycan	231-239	alpha-mannosidase	Saccharomyces cerevisiae S288C	90-95
19302290-1	2009	Alpha1,6-fucosyltransferase (Fut8), an enzyme that catalyzes the introduction of alpha1,6 core fucose to the innermost N-acetylglucosamine residue of the N-glycan, has been implicated in the development, immune system, and tumorigenesis.	n-glycan	154-162	fucosyltransferase 8	Homo sapiens	0-27
19302290-1	2009	Alpha1,6-fucosyltransferase (Fut8), an enzyme that catalyzes the introduction of alpha1,6 core fucose to the innermost N-acetylglucosamine residue of the N-glycan, has been implicated in the development, immune system, and tumorigenesis.	n-glycan	154-162	fucosyltransferase 8	Homo sapiens	29-33
19302290-1	2009	Alpha1,6-fucosyltransferase (Fut8), an enzyme that catalyzes the introduction of alpha1,6 core fucose to the innermost N-acetylglucosamine residue of the N-glycan, has been implicated in the development, immune system, and tumorigenesis.	n-glycan	154-162	adrenoceptor alpha 1D	Homo sapiens	81-89
18844296-5	2009	Glycan MS analyses in CDG-II is mandatory to detect whenever possible a repertoire of structures to pinpoint candidate enzymes and genes responsible for the abnormal N-glycan synthesis.	n-glycan	166-174	ALG2 alpha-1,3/1,6-mannosyltransferase	Homo sapiens	22-28
19714866-11	2009	The N-terminal N-glycan of NEU1 is indispensable for its function, whereas the C-terminal N-glycan appears to be non-essential.	n-glycan	15-23	neuraminidase 1	Homo sapiens	27-31
19714866-12	2009	The omission of the second N-glycan can be compensated for by upregulating the expression of PPCA.	n-glycan	27-35	cathepsin A	Homo sapiens	93-97
19129245-0	2009	Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116.	n-glycan	19-27	myelin basic protein	Homo sapiens	40-62
19129245-0	2009	Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116.	n-glycan	19-27	dipeptidyl peptidase 4	Homo sapiens	89-93
19129245-0	2009	Highly fucosylated N-glycan ligands for mannan-binding protein expressed specifically on CD26 (DPPVI) isolated from a human colorectal carcinoma cell line, SW1116.	n-glycan	19-27	dipeptidyl peptidase like 6	Homo sapiens	95-100
19124464-8	2009	These results indicate that GM3-mediated inhibition of EGFR phosphorylation is caused by interaction of GM3 with GlcNAc-terminated N-glycan on EGFR.	n-glycan	131-139	epidermal growth factor receptor	Homo sapiens	55-59
19164298-0	2009	N-Glycan Moieties in Neonatal Fc Receptor Determine Steady-state Membrane Distribution and Directional Transport of IgG.	n-glycan	0-8	Fc gamma receptor and transporter	Homo sapiens	21-41
19164298-3	2009	We hypothesized that these differences may be due to the additional N-glycans expressed on the rat FcRn, because N-glycans have been proposed to function as apical targeting signals, and that two of the N-glycan moieties have been shown to contribute to the IgG binding of rat FcRn.	n-glycan	68-76	Fc gamma receptor and transporter	Rattus norvegicus	99-103
19164298-4	2009	A panel of mutant human FcRn variants was generated to resemble the N-glycan expression of rat FcRn in various combinations and subsequently transfected into Madin-Darby canine kidney II cells together with human beta2-microglobulin.	n-glycan	68-76	Fc gamma receptor and transporter	Homo sapiens	24-28
19164298-4	2009	A panel of mutant human FcRn variants was generated to resemble the N-glycan expression of rat FcRn in various combinations and subsequently transfected into Madin-Darby canine kidney II cells together with human beta2-microglobulin.	n-glycan	68-76	Fc gamma receptor and transporter	Rattus norvegicus	95-99
19164298-5	2009	Mutant human FcRn clones that contained additional N-glycan side-chain modifications, including that which was fully rodentized, still exhibited specificity for human IgG and failed to bind to mouse IgG.	n-glycan	51-59	Fc gamma receptor and transporter	Homo sapiens	13-17
19124464-8	2009	These results indicate that GM3-mediated inhibition of EGFR phosphorylation is caused by interaction of GM3 with GlcNAc-terminated N-glycan on EGFR.	n-glycan	131-139	epidermal growth factor receptor	Homo sapiens	143-147
19093875-3	2009	The most abundant neutral N-glycan has a composition of Hex(7)HexNAc(4)dHex(1), Negative ion ESI-MS/MS confirmed the presence of the alpha1-3-Gal-Gal motif on each arm of the fucosylated biantennary N-glycan.	n-glycan	26-34	adrenoceptor alpha 1D	Homo sapiens	133-141
19204290-1	2009	The folding energetics of the mono-N-glycosylated adhesion domain of the human immune cell receptor cluster of differentiation 2 (hCD2ad) were studied systematically to understand the influence of the N-glycan on the folding energy landscape.	n-glycan	201-209	CD2 molecule	Homo sapiens	130-134
19054802-4	2009	In the present work, we investigated the substantial effects of GlcNAcase on N-glycan patterns in Drosophila S2 cells using two GlcNAcase suppression strategies: an mRNA-targeting approach using RNA interference (RNAi) and a protein-targeting approach using the specific chemical inhibitor 2-acetamido-1,2-dideoxynojirimycin (2-ADN).	n-glycan	77-85	O-GlcNAcase	Drosophila melanogaster	64-73
19054802-5	2009	Using high-performance liquid chromatography (HPLC) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analyses, we found that the N-glycosylation patterns of human erythropoietin (hEPO) secreted by stably transfected S2 cells were more complex following GlcNAcase suppression, which generated N-glycan structures with a terminal GlcNAc and/or galactose.	n-glycan	339-347	erythropoietin	Homo sapiens	210-224
19159617-4	2009	Detailed mass spectrometry analysis demonstrated a new N-glycosylation site containing a potential complex type N-glycan in E-cadherin from a mammary carcinoma cell line.	n-glycan	112-120	cadherin 1	Canis lupus familiaris	124-134
19133226-0	2009	Active 1918 pandemic flu viral neuraminidase has distinct N-glycan profile and is resistant to trypsin digestion.	n-glycan	58-66	neuraminidase 1	Homo sapiens	31-44
19154352-9	2009	Our data demonstrate that secreted rmDNase1 and murine parotid DNase1 are mixtures of three different di-N-glycosylated molecules containing two high-mannose, two complex N-glycans or one high-mannose and one complex N-glycan moiety.	n-glycan	171-179	deoxyribonuclease I	Mus musculus	37-43
19140676-8	2009	The serum N-glycan profile is a promising noninvasive method for detecting NASH or NASH-related fibrosis in NAFLD patients, which could be a valuable supplement to other markers currently used in diagnosis of NASH.	n-glycan	10-18	SAM domain, SH3 domain and nuclear localization signals 1	Homo sapiens	75-79
19140676-8	2009	The serum N-glycan profile is a promising noninvasive method for detecting NASH or NASH-related fibrosis in NAFLD patients, which could be a valuable supplement to other markers currently used in diagnosis of NASH.	n-glycan	10-18	SAM domain, SH3 domain and nuclear localization signals 1	Homo sapiens	83-87
19140676-8	2009	The serum N-glycan profile is a promising noninvasive method for detecting NASH or NASH-related fibrosis in NAFLD patients, which could be a valuable supplement to other markers currently used in diagnosis of NASH.	n-glycan	10-18	SAM domain, SH3 domain and nuclear localization signals 1	Homo sapiens	83-87
19088067-7	2009	After transfection in COS7 cells, the three FUT10s and at least one FUT11, link alpha-l-fucose onto conalbumin glycopeptides and biantennary N-glycan acceptors but not onto short lactosaminyl acceptor substrates as do classical monoexonic alpha1,3-fucosyltransferases.	n-glycan	141-149	fucosyltransferase 11	Homo sapiens	68-73
19088067-8	2009	Modifications of the innermost core GlcNAc of the N-glycan, by substitution with ManNAc or with an opened GlcNAc ring or by the addition of an alpha1,6-fucose, suggest that the FUT10 transfer is performed on the innermost GlcNAc of the core chitobiose.	n-glycan	50-58	fucosyltransferase 10	Homo sapiens	177-182
19088067-9	2009	We can exclude alpha1,3-fucosylation of the two peripheral GlcNAcs linked to the trimannosyl core of the acceptor, because the FUT10 fucosylated biantennary N-glycan product loses both terminal GlcNAc residues after digestion with human placenta alpha-N-acetylglucosaminidase.	n-glycan	157-165	fucosyltransferase 10	Homo sapiens	127-132
19088067-9	2009	We can exclude alpha1,3-fucosylation of the two peripheral GlcNAcs linked to the trimannosyl core of the acceptor, because the FUT10 fucosylated biantennary N-glycan product loses both terminal GlcNAc residues after digestion with human placenta alpha-N-acetylglucosaminidase.	n-glycan	157-165	N-acetyl-alpha-glucosaminidase	Homo sapiens	246-275
19093875-3	2009	The most abundant neutral N-glycan has a composition of Hex(7)HexNAc(4)dHex(1), Negative ion ESI-MS/MS confirmed the presence of the alpha1-3-Gal-Gal motif on each arm of the fucosylated biantennary N-glycan.	n-glycan	199-207	adrenoceptor alpha 1D	Homo sapiens	133-141
19171304-4	2009	Fluorescence-based screening demonstrated that Gal-1 recognizes a wide variety of complex N-glycans, whereas Gal-3 primarily recognizes poly-N-acetyllactosamine-containing glycans independent of N-glycan presentation.	n-glycan	90-98	galectin 1	Homo sapiens	47-52
19055608-8	2009	Confocal microscopy showed that apoplast and ER-targeted EPO were correctly localized, and N-glycan analysis demonstrated that complex plant glycans existed on apoplast-targeted EPO, but not on ER-targeted EPO.	n-glycan	91-99	erythropoietin	Homo sapiens	178-181
19055608-8	2009	Confocal microscopy showed that apoplast and ER-targeted EPO were correctly localized, and N-glycan analysis demonstrated that complex plant glycans existed on apoplast-targeted EPO, but not on ER-targeted EPO.	n-glycan	91-99	erythropoietin	Homo sapiens	178-181
19124653-6	2009	The Htm1p exomannosidase activity requires processing of the N-glycan by glucosidase I, glucosidase II, and mannosidase I, resulting in a sequential order of specific N-glycan structures that reflect the folding status of the glycoprotein.	n-glycan	61-69	mannosyl-oligosaccharide glucosidase	Homo sapiens	73-121
19101978-1	2009	Mannostatin A is a potent inhibitor of the mannose-trimming enzyme, Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan processing pathway.	n-glycan	126-134	alpha-Mannosidase class II a	Drosophila melanogaster	68-94
19101978-1	2009	Mannostatin A is a potent inhibitor of the mannose-trimming enzyme, Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan processing pathway.	n-glycan	126-134	alpha-Mannosidase class II a	Drosophila melanogaster	96-100
19124653-6	2009	The Htm1p exomannosidase activity requires processing of the N-glycan by glucosidase I, glucosidase II, and mannosidase I, resulting in a sequential order of specific N-glycan structures that reflect the folding status of the glycoprotein.	n-glycan	167-175	mannosyl-oligosaccharide glucosidase	Homo sapiens	73-121
19415110-8	2009	Furthermore, analysis of Chp from a mutant (RNAi against dolichyl-phosphate alpha-d-mannosyltransferase), which affects N-glycan synthesis in the ER, revealed that truncated glycan structures were processed.	n-glycan	120-128	chaoptin	Drosophila melanogaster	25-28
18778316-11	2009	The method described offers the advantage that it can be implemented in any desired plant system for effective removal of beta(1,2)-xylose and alpha(1,3)-fucose from the N-glycan.	n-glycan	170-178	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	122-130
18778316-11	2009	The method described offers the advantage that it can be implemented in any desired plant system for effective removal of beta(1,2)-xylose and alpha(1,3)-fucose from the N-glycan.	n-glycan	170-178	adrenoceptor alpha 1D	Homo sapiens	143-152
19421409-5	2009	RESULTS: High mannose, bi and tri-antennary nonbisected and bisected complex N-glycan, N-acetyl glucosamine and galactose were expressed by drusen, retinal pigment epithelium, Bruch"s membrane, and photoreceptors while N-acetyl galactosamine and fucose were absent; treatment with neuraminidase exposed subterminal galactose in both sites and sparse N-acetyl galactosamine residues in drusen alone.	n-glycan	77-85	neuraminidase 1	Homo sapiens	281-294
18804089-7	2008	Furthermore, the N-glycan analysis indicated a lower heterogeneity from epoetin delta when compared with its CHO homologue, being predominantly tetraantennary without N-acetyllactosamine repeats in the former.	n-glycan	17-25	erythropoietin	Homo sapiens	72-79
18558690-1	2008	Inhibition of Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan processing pathway, provides a route to blocking cancer-induced changes in cell surface oligosaccharide structures.	n-glycan	72-80	mannosidase alpha class 2A member 1	Homo sapiens	14-40
18930512-2	2008	To reveal the underlying mechanisms, a broad variety of 31 different virus strains containing one or several N-glycan deletions in V1/V2 of the gp120 of the X4-tropic HIV-1(NL4.3) were constructed by chimeric virus technology.	n-glycan	109-117	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	144-149
18491227-2	2008	In a previous study, we demonstrated that all of four potential N-glycosylation sites in E-cadherin are occupied by N-glycans in human breast carcinoma cells in vivo and the elimination of N-glycan at Asn-633 dramatically affected E-cadherin expression and made it degraded.	n-glycan	116-124	cadherin 1	Homo sapiens	89-99
18491227-2	2008	In a previous study, we demonstrated that all of four potential N-glycosylation sites in E-cadherin are occupied by N-glycans in human breast carcinoma cells in vivo and the elimination of N-glycan at Asn-633 dramatically affected E-cadherin expression and made it degraded.	n-glycan	116-124	cadherin 1	Homo sapiens	231-241
18521746-3	2008	We purified the secreted forms of wild-type and mutant human APPs (both the Swedish type and the London type) produced by transfected C17 cells and determined the N-glycan structures of these three recombinant APPs.	n-glycan	163-171	cathepsin B	Homo sapiens	210-214
18768906-2	2008	STT3a encodes a subunit of oligosaccharyltransferase that affects efficiency of N-glycan transfer to nascent secretory proteins in the endoplasmic reticulum; cgl1 mutants lack N-acetyl-glucosaminyltransferase I activity and are unable to form complex N-glycans in the Golgi apparatus.	n-glycan	80-88	staurosporin and temperature sensitive 3-like A	Arabidopsis thaliana	0-5
18768906-2	2008	STT3a encodes a subunit of oligosaccharyltransferase that affects efficiency of N-glycan transfer to nascent secretory proteins in the endoplasmic reticulum; cgl1 mutants lack N-acetyl-glucosaminyltransferase I activity and are unable to form complex N-glycans in the Golgi apparatus.	n-glycan	80-88	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	158-162
18826328-4	2008	Analytical ultracentrifugation revealed wide variation in the distribution of polymeric species between IgA1 samples, and Fourier transform ion cyclotron resonance mass spectrometry showed overlapping but distinct populations of N-glycan species between IgA1 samples.	n-glycan	229-237	immunoglobulin heavy constant alpha 1	Homo sapiens	254-258
19262156-5	2008	Here, we will focus on the positive and negative regulation of biological functions of integrins by the remodeling of N-glycans with N-acetylglucosaminyltransferase III (GnT-III) and N-acetylglucosaminyltransferase V (GnT-V), which catalyze branched N-glycan formations, bisecting GlcNAc and beta1,6 GlcNAc, respectively.	n-glycan	118-126	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	170-177
19262156-5	2008	Here, we will focus on the positive and negative regulation of biological functions of integrins by the remodeling of N-glycans with N-acetylglucosaminyltransferase III (GnT-III) and N-acetylglucosaminyltransferase V (GnT-V), which catalyze branched N-glycan formations, bisecting GlcNAc and beta1,6 GlcNAc, respectively.	n-glycan	118-126	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	218-223
18633135-4	2008	Inhibition of N-glycan processing blocked surface binding of dGal-1 and prevented dGal-1-induced Ca(2+) mobilization and phosphatidylserine exposure.	n-glycan	14-22	Galactose-specific C-type lectin	Drosophila melanogaster	61-67
18633135-4	2008	Inhibition of N-glycan processing blocked surface binding of dGal-1 and prevented dGal-1-induced Ca(2+) mobilization and phosphatidylserine exposure.	n-glycan	14-22	Galactose-specific C-type lectin	Drosophila melanogaster	82-88
18632981-0	2008	Consequences of individual N-glycan deletions and of proteasomal inhibition on secretion of active BACE.	n-glycan	27-35	beta-secretase 1	Homo sapiens	99-103
19704526-3	2008	Recently, we have investigated the role of complex N-glycans in plants using a series of Arabidopsis thaliana mutants affected in complex N-glycan biosynthesis.1 Several mutant plants including complex glycan 1 (cgl1) displayed a salt-sensitive phenotype during their root growth, which was associated with radial swelling and loss of apical dominance.	n-glycan	51-59	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	194-210
19704526-6	2008	This establishes that plant complex N-glycan modification is important for the in vivo function of KOR1/RSW2.	n-glycan	36-44	glycosyl hydrolase 9A1	Arabidopsis thaliana	99-103
19704526-6	2008	This establishes that plant complex N-glycan modification is important for the in vivo function of KOR1/RSW2.	n-glycan	36-44	glycosyl hydrolase 9A1	Arabidopsis thaliana	104-108
18754874-0	2008	N-Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor.	n-glycan	0-8	epidermal growth factor receptor	Homo sapiens	25-57
18754874-0	2008	N-Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor.	n-glycan	0-8	epidermal growth factor receptor	Homo sapiens	105-137
18558690-1	2008	Inhibition of Golgi alpha-mannosidase II (GMII), which acts late in the N-glycan processing pathway, provides a route to blocking cancer-induced changes in cell surface oligosaccharide structures.	n-glycan	72-80	mannosidase alpha class 2A member 1	Homo sapiens	42-46
18467454-0	2008	Functional characterization of HFR1, a high-mannose N-glycan-specific wheat lectin induced by Hessian fly larvae.	n-glycan	52-60	uncharacterized protein LOC542941	Triticum aestivum	31-35
18408158-3	2008	Herein, we provide evidence that mutants defective in N-glycan maturation, such as complex glycan 1 (cgl1), are more salt-sensitive than wild type.	n-glycan	54-62	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	83-99
18479159-1	2008	The N-glycan structures of the Lens culinaris agglutinin (LCA)-reactive fraction of alpha-fetoprotein (AFP-L3), a tumor marker of hepatocellular carcinomas (HCC), were analyzed in relationship to glycosyltransferases and LCA-affinity electrophoresis.	n-glycan	4-12	alpha fetoprotein	Homo sapiens	103-106
18479159-2	2008	Using HPLC and MALDI-TOF MS, we determined the N-glycan structures of AFP from HCC cell lines, and demonstrated they were affected by N-acetylglucosaminyltransferase III and fucosyltransferase VIII, but not by N-acetylglucosaminyltransferase V.	n-glycan	47-55	alpha fetoprotein	Homo sapiens	70-73
18479159-3	2008	Moreover, we identified the N-glycan structures of AFP in HCC patients.	n-glycan	28-36	alpha fetoprotein	Homo sapiens	51-54
18567790-0	2008	Identification of the gene encoding the alpha1,3-mannosyltransferase (ALG3) in Arabidopsis and characterization of downstream n-glycan processing.	n-glycan	126-134	asparagine-linked glycosylation 3	Arabidopsis thaliana	70-74
18567790-5	2008	N-glycan analysis of alg3-2 and alg3-2 in the complex-glycan-less mutant background, which lacks N-acetylglucosaminyl-transferase I activity, reveals that when ALG3 activity is strongly reduced, almost all N-glycans transferred to proteins are aberrant, indicating that the Arabidopsis oligosaccharide transferase complex is remarkably substrate tolerant.	n-glycan	0-8	asparagine-linked glycosylation 3	Arabidopsis thaliana	21-25
18567790-5	2008	N-glycan analysis of alg3-2 and alg3-2 in the complex-glycan-less mutant background, which lacks N-acetylglucosaminyl-transferase I activity, reveals that when ALG3 activity is strongly reduced, almost all N-glycans transferred to proteins are aberrant, indicating that the Arabidopsis oligosaccharide transferase complex is remarkably substrate tolerant.	n-glycan	0-8	asparagine-linked glycosylation 3	Arabidopsis thaliana	32-36
18567790-5	2008	N-glycan analysis of alg3-2 and alg3-2 in the complex-glycan-less mutant background, which lacks N-acetylglucosaminyl-transferase I activity, reveals that when ALG3 activity is strongly reduced, almost all N-glycans transferred to proteins are aberrant, indicating that the Arabidopsis oligosaccharide transferase complex is remarkably substrate tolerant.	n-glycan	0-8	asparagine-linked glycosylation 3	Arabidopsis thaliana	160-164
18214858-3	2008	In the present study, site-specific N-glycan structures of haptoglobin in sera obtained from patients with PC or chronic pancreatitis (CP) were analyzed using liquid chromatography-electrospray ionization mass spectrometry.	n-glycan	36-44	haptoglobin	Homo sapiens	59-70
17979184-5	2008	Removal of N-glycan at Asn-633 dramatically affected E-cadherin stability.	n-glycan	11-19	cadherin 1	Homo sapiens	53-63
18410496-11	2008	Our data further demonstrate that both the extent of the N-linked glycan and its distance from the plasma membrane affect Mid2p function, suggesting the N-glycan to be directly involved in Mid2p sensing.	n-glycan	153-161	Mid2p	Saccharomyces cerevisiae S288C	122-127
18410496-11	2008	Our data further demonstrate that both the extent of the N-linked glycan and its distance from the plasma membrane affect Mid2p function, suggesting the N-glycan to be directly involved in Mid2p sensing.	n-glycan	153-161	Mid2p	Saccharomyces cerevisiae S288C	189-194
18342252-12	2008	Sequence comparisons with other enzymatically characterized insect homologs suggested that TcFDL, unlike the other NAGs, may have a role in N-glycan processing in addition to its apparent role in cuticular chitin turnover.	n-glycan	140-148	fused lobes	Tribolium castaneum	91-96
18264945-0	2008	Similarities between N-glycan glycoform of tonsillar IgA1 and that of aberrant IgA1 abundant in IgA nephropathy patient serum.	n-glycan	21-29	immunoglobulin heavy constant alpha 1	Homo sapiens	53-57
18036567-0	2008	N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.	n-glycan	0-8	epidermal growth factor receptor	Homo sapiens	12-16
18036567-7	2008	These findings suggest that the specific N-glycan in domain III of ErbB family plays an essential role in regulating receptor dimerization and transforming activity.	n-glycan	41-49	epidermal growth factor receptor	Homo sapiens	67-71
18203810-2	2008	A major concern is the presence of beta 1,2-xylose and core alpha 1,3-fucose residues on complex N-glycans as these nonmammalian N-glycan residues may provoke unwanted side effects in humans.	n-glycan	97-105	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	35-43
18203810-2	2008	A major concern is the presence of beta 1,2-xylose and core alpha 1,3-fucose residues on complex N-glycans as these nonmammalian N-glycan residues may provoke unwanted side effects in humans.	n-glycan	97-105	adrenoceptor alpha 1D	Homo sapiens	60-69
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	mannoside acetylglucosaminyltransferase 5	Mus musculus	0-33
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	mannoside acetylglucosaminyltransferase 5	Mus musculus	35-40
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	mannoside acetylglucosaminyltransferase 5	Mus musculus	44-49
18292539-1	2008	N-acetylglucosaminyltransferase V (Mgat5 or GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	Mus musculus	79-86
18364742-2	2008	This study provides the first evidence that voltage-gated K+ channels Kv3.1, Kv3.3, and Kv3.4, possess distinct sialylated N-glycan structures throughout the central nervous system of the adult rat.	n-glycan	123-131	potassium voltage-gated channel subfamily C member 1	Rattus norvegicus	70-75
18364742-2	2008	This study provides the first evidence that voltage-gated K+ channels Kv3.1, Kv3.3, and Kv3.4, possess distinct sialylated N-glycan structures throughout the central nervous system of the adult rat.	n-glycan	123-131	potassium voltage-gated channel subfamily C member 3	Rattus norvegicus	77-82
18364742-2	2008	This study provides the first evidence that voltage-gated K+ channels Kv3.1, Kv3.3, and Kv3.4, possess distinct sialylated N-glycan structures throughout the central nervous system of the adult rat.	n-glycan	123-131	potassium voltage-gated channel subfamily C member 4	Homo sapiens	88-93
17846903-7	2008	High mannose, bi/tri-nonbisected and bisected complex N-glycan, N-acetyl glucosaminyl, galactosyl and sialyl residues were found to be expressed by drusen, while treatment with neuraminidase exposed subterminal N-acetyl galactosamine and galactosyl residues.	n-glycan	54-62	neuraminidase 1	Homo sapiens	177-190
18083109-5	2008	These findings, emphasizing the difference in the N-glycan repertoire between the rhEPO-milk and EPO-GMGE, are consistent with the principle that glycosylation is cell-type dependent and that the cell environment is crucial as well.	n-glycan	50-58	erythropoietin	Homo sapiens	84-87
18235976-5	2008	Removal of N-glycan at Asn633 dramatically affected E-cadherin stability.	n-glycan	11-19	cadherin 1	Homo sapiens	52-62
18264945-0	2008	Similarities between N-glycan glycoform of tonsillar IgA1 and that of aberrant IgA1 abundant in IgA nephropathy patient serum.	n-glycan	21-29	immunoglobulin heavy variable 4-38-2-like	Homo sapiens	53-56
18264945-4	2008	Therefore, analyses of the N-glycan glycoform on serum IgA1, aberrant IgA1 and tonsillar IgA1 were carried out using the 3-dimensional mapping method.	n-glycan	27-35	immunoglobulin heavy constant alpha 1	Homo sapiens	55-59
18264945-4	2008	Therefore, analyses of the N-glycan glycoform on serum IgA1, aberrant IgA1 and tonsillar IgA1 were carried out using the 3-dimensional mapping method.	n-glycan	27-35	immunoglobulin heavy constant alpha 1	Homo sapiens	70-74
18264945-4	2008	Therefore, analyses of the N-glycan glycoform on serum IgA1, aberrant IgA1 and tonsillar IgA1 were carried out using the 3-dimensional mapping method.	n-glycan	27-35	immunoglobulin heavy constant alpha 1	Homo sapiens	70-74
18264945-7	2008	The neutral complex-type N-glycan chain with fucose was higher in both the aberrant IgA1 and tonsillar IgA1 than in the serum IgA1.	n-glycan	25-33	immunoglobulin heavy constant alpha 1	Homo sapiens	84-88
18264945-7	2008	The neutral complex-type N-glycan chain with fucose was higher in both the aberrant IgA1 and tonsillar IgA1 than in the serum IgA1.	n-glycan	25-33	immunoglobulin heavy constant alpha 1	Homo sapiens	103-107
18264945-7	2008	The neutral complex-type N-glycan chain with fucose was higher in both the aberrant IgA1 and tonsillar IgA1 than in the serum IgA1.	n-glycan	25-33	immunoglobulin heavy constant alpha 1	Homo sapiens	103-107
17933909-2	2007	N glycosylation is a posttranslational modification that is initiated in the endoplasmic reticulum (ER), where the Glc(3)Man(9)GlcNAc(2) N-glycan is processed by alpha-glucosidases I and II and alpha1,2-mannosidase to generate Man(8)GlcNAc(2).	n-glycan	137-145	mannosidase alpha class 1A member 2	Homo sapiens	194-214
18931531-1	2008	OBJECTIVE: N-acetylglucosaminyltransferase V (GnT-V) is a key enzyme that catalyzes beta(1-6) branching of N-acetylglucosamine on N-glycan of cell proteins, some of which are linked with metastasis.	n-glycan	130-138	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	11-44
18931531-1	2008	OBJECTIVE: N-acetylglucosaminyltransferase V (GnT-V) is a key enzyme that catalyzes beta(1-6) branching of N-acetylglucosamine on N-glycan of cell proteins, some of which are linked with metastasis.	n-glycan	130-138	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	46-51
17522223-2	2007	Here, we delineate the N-linked glycosylation (N-glycan) sites in gp120 that contribute to optimal DC-SIGN binding.	n-glycan	47-55	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	66-71
17636254-7	2007	Furthermore, a deletion of part of the Caenorhabditis hex-2 gene drastically reduces the native N-glycan-specific hexosaminidase activity in mutant worm extracts and results in a shift in the N-glycan profile, which is a demonstration of its in vivo enzymatic relevance.	n-glycan	96-104	Beta-N-acetylhexosaminidase	Caenorhabditis elegans	114-128
17692467-0	2007	Distinct N-glycan glycosylation of P-glycoprotein isolated from the human uterine sarcoma cell line MES-SA/Dx5.	n-glycan	9-17	ATP binding cassette subfamily B member 1	Homo sapiens	35-49
17661134-7	2007	Matrix assisted laser desoption/ionization time of flight mass spectrometry (MALDI TOF/MS) analysis of the N-glycan structure of the mnn1 och1 mutant revealed that the main component is Man(8)GlcNAc(2).	n-glycan	107-115	alpha-1,3-mannosyltransferase MNN1	Saccharomyces cerevisiae S288C	133-142
17644627-6	2007	With N-glycan substrates, HEXO1 displayed a much higher specific activity than HEXO2 and HEXO3.	n-glycan	5-13	beta-hexosaminidase 1	Arabidopsis thaliana	26-31
17644627-6	2007	With N-glycan substrates, HEXO1 displayed a much higher specific activity than HEXO2 and HEXO3.	n-glycan	5-13	beta-hexosaminidase 2	Arabidopsis thaliana	79-84
17644627-6	2007	With N-glycan substrates, HEXO1 displayed a much higher specific activity than HEXO2 and HEXO3.	n-glycan	5-13	beta-hexosaminidase 3	Arabidopsis thaliana	89-94
17644627-10	2007	These results indicate that HEXO1 participates in N-glycan trimming in the vacuole, whereas HEXO2 and/or HEXO3 could be responsible for the processing of N-glycans present on secretory glycoproteins.	n-glycan	50-58	beta-hexosaminidase 1	Arabidopsis thaliana	28-33
17570337-5	2007	Investigation of the total N-glycan pool of human erythropoietin (rhEPO) expressed in GMGE cells by monosaccharide analysis, HPLC profiling, and mass spectrometry, indicated significant differences with respect to the same protein expressed in Chinese hamster ovary (CHO) cells.	n-glycan	27-35	erythropoietin	Homo sapiens	50-64
17942907-6	2007	Finally, regulation of ROS, glucose uptake, and sensitivities to EGF and TGF-beta were rescued by Mgat5 expression or by hexosamine supplementation to complex N-glycan biosynthesis in Mgat5-/- cells.	n-glycan	159-167	mannoside acetylglucosaminyltransferase 5	Mus musculus	184-189
17591618-0	2007	Site-specific N-glycan characterization of human complement factor H.	n-glycan	14-22	complement factor H	Homo sapiens	49-68
17678502-3	2007	A major concern is the presence of beta1,2-xylose and core alpha1,3-fucose residues on complex N-linked glycans, as these N-glycan epitopes are immunogenic in mammals.	n-glycan	122-130	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	35-42
17678502-3	2007	A major concern is the presence of beta1,2-xylose and core alpha1,3-fucose residues on complex N-linked glycans, as these N-glycan epitopes are immunogenic in mammals.	n-glycan	122-130	adrenoceptor alpha 1D	Homo sapiens	59-67
18051874-3	2007	alpha-1,6-mannosyltransferases gene (och1) encodes the enzyme that initiates the first step of out-chain elongation of high mannose type N-glycan in yeast, which is different from that in human.	n-glycan	137-145	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	37-41
18051874-8	2007	Different with the hyperglycosylated HSA/GM-CSF chimera expressed in wild type P. pastoris, the chimera expressed in the och1 deletion strain, contained smaller N-glycan.	n-glycan	161-169	initiation-specific alpha-1,6-mannosyltransferase	Saccharomyces cerevisiae S288C	121-125
17636988-4	2007	(1) Removal of entire N-glycan chains by peptide-N-glycosidase (PNGase) digestion, with concomitant deamidation of the released asparagine residue.	n-glycan	22-30	N-glycanase 1	Homo sapiens	41-62
17636988-4	2007	(1) Removal of entire N-glycan chains by peptide-N-glycosidase (PNGase) digestion, with concomitant deamidation of the released asparagine residue.	n-glycan	22-30	N-glycanase 1	Homo sapiens	64-70
17636988-6	2007	(2) Digestion with two endo-beta-N-acetylglucosaminidases (Endo D and Endo H) that cleave the glycosidic bond between the two N-acetylglucosamine (GlcNAc) residues in the conserved N-glycan core structure, leaving single GlcNAc residues with putative fucosyl side chains attached to the peptide.	n-glycan	181-189	mannosidase endo-alpha	Homo sapiens	23-27
17636988-6	2007	(2) Digestion with two endo-beta-N-acetylglucosaminidases (Endo D and Endo H) that cleave the glycosidic bond between the two N-acetylglucosamine (GlcNAc) residues in the conserved N-glycan core structure, leaving single GlcNAc residues with putative fucosyl side chains attached to the peptide.	n-glycan	181-189	mannosidase endo-alpha	Homo sapiens	59-63
17636988-6	2007	(2) Digestion with two endo-beta-N-acetylglucosaminidases (Endo D and Endo H) that cleave the glycosidic bond between the two N-acetylglucosamine (GlcNAc) residues in the conserved N-glycan core structure, leaving single GlcNAc residues with putative fucosyl side chains attached to the peptide.	n-glycan	181-189	mannosidase endo-alpha	Homo sapiens	70-74
17522223-2	2007	Here, we delineate the N-linked glycosylation (N-glycan) sites in gp120 that contribute to optimal DC-SIGN binding.	n-glycan	47-55	CD209 molecule	Homo sapiens	99-106
17497937-8	2007	The predominant presentation of the two branches in the disubstituted N-glycan as extended (alpha1,3-antenna) and backfolded (alpha1,6-antenna) forms, revealed by molecular dynamics simulations, can underlie the measured characteristics.	n-glycan	70-78	cholinergic receptor, nicotinic, alpha polypeptide 3	Mus musculus	92-100
17606910-6	2007	N-glycan-dependent QC of folding (UDP-Glc:glycoprotein glucosyltransferase, calreticulin, and/or calnexin) was present and active in some but not all protists containing at least five mannose residues in their N-glycans and was absent in protists lacking Man.	n-glycan	0-8	calreticulin	Homo sapiens	76-88
17606910-6	2007	N-glycan-dependent QC of folding (UDP-Glc:glycoprotein glucosyltransferase, calreticulin, and/or calnexin) was present and active in some but not all protists containing at least five mannose residues in their N-glycans and was absent in protists lacking Man.	n-glycan	0-8	calnexin	Homo sapiens	97-105
17340198-3	2007	IL-1alpha recognized a di-antennary N-glycan with two alpha2-3-linked sialic acid residues, whereas IL-1beta recognized the GM(4), a alpha2-3-linked sialylated glycosphingolipid.	n-glycan	36-44	interleukin 1 alpha	Homo sapiens	0-9
17400585-5	2007	Pten heterozygosity was associated with increased surface beta1,6GlcNAc-branched N-glycans, suggesting positive feedback from PI3K signaling to N-glycan branching.	n-glycan	81-89	phosphatase and tensin homolog	Mus musculus	0-4
17630273-6	2007	Recombinant GALT1 protein produced in insect cells was capable of transferring beta1,3-linked galactose residues to various N-glycan acceptor substrates, and subsequent treatment of the reaction products with alpha1,4-fucosyltransferase resulted in the generation of Lewis a structures.	n-glycan	124-132	galactosyltransferase1	Arabidopsis thaliana	12-17
17082223-8	2007	To determine whether a specific glycosylation site or the number of glycans was critical for protein stability, we studied the protein expression of combinations of N-glycan-deficient mutants and observed that Bsep with one glycan was considerably unstable compared with Bsep harboring two or more glycans.	n-glycan	165-173	ATP binding cassette subfamily B member 11	Rattus norvegicus	210-214
17420569-0	2007	Evidence for new beta1-3 galactosyltransferase activity involved in biosynthesis of unusual N-glycan harboring T-antigen in Apis mellifera.	n-glycan	92-100	beta-1,3-galactosyltransferase	Apis mellifera	17-46
17420569-4	2007	So far, such beta1-3galactosyltransferase activity, which can transfer galactosyl residues with the beta1-3 linkage to beta1-4 GalNAc residues in N-glycan, has not been found among any eucaryotic cells.	n-glycan	146-154	beta-1,3-galactosyltransferase	Apis mellifera	13-41
17420569-5	2007	But using GalNAc(2)GlcNAc(2)Man(3)GlcNAc(2)-PA as acceptor N-glycan, we detected the beta1-3 galactosyltransferase activity in membrane fraction prepared from honeybee cephalic portions.	n-glycan	59-67	beta-1,3-galactosyltransferase	Apis mellifera	85-114
17420569-6	2007	This result indicates that honeybee expresses a unique beta1-3 galactosyltransferase involved in biosynthesis of the unusual N-glycan containing a tumor related antigen in the hypopharyngeal gland.	n-glycan	125-133	beta-1,3-galactosyltransferase	Apis mellifera	55-84
17293352-6	2007	The N-linked glycans of recombinant human GAA (rhAGLU), isolated from the rabbit milk, were released by peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase F. The N-glycan pool was fractionated and purified into individual components by a combination of anion-exchange, normal-phase, and Sambucus nigra agglutinin-affinity chromatography.	n-glycan	171-179	alpha glucosidase	Homo sapiens	42-45
17370997-5	2007	Moreover, the PNGase F treatment of the glycoproteins, which cleaves the N-linked oligosaccharide chain, shows that the modified sugar has been transferred to the N-glycan chains of the glycoproteins and not to the protein portion.	n-glycan	163-171	N-glycanase 1	Homo sapiens	14-20
17334369-6	2007	Our results demonstrate the critical function of N-glycan-linked 6-sulfo sialyl Lewis X in L-selectin-dependent lymphocyte homing and recruitment.	n-glycan	49-57	selectin, lymphocyte	Mus musculus	91-101
17154134-3	2006	It was demonstrated that the ZIC-HILIC separation column has a selectivity for sialylated N-glycopeptides and a high capability for separation based on the structural recognition of sialylated N-glycan isomers as well as for the previously reported neutral N-glycans and N-glycopeptides.	n-glycan	193-201	Zic family member 1	Homo sapiens	29-32
17332320-0	2007	The Asn418-linked N-glycan of ErbB3 plays a crucial role in preventing spontaneous heterodimerization and tumor promotion.	n-glycan	18-26	receptor tyrosine-protein kinase erbB-3	Cricetulus griseus	30-35
17332320-8	2007	These findings suggest that the Asn(418)-linked N-glycan in ErbB3 plays an essential role in regulating receptor heterodimerization with ErbB2 and might have an effect on transforming activity.	n-glycan	48-56	receptor tyrosine-protein kinase erbB-3	Cricetulus griseus	60-65
17332320-8	2007	These findings suggest that the Asn(418)-linked N-glycan in ErbB3 plays an essential role in regulating receptor heterodimerization with ErbB2 and might have an effect on transforming activity.	n-glycan	48-56	receptor tyrosine-protein kinase erbB-2	Cricetulus griseus	137-142
17222224-0	2007	Influence of N-glycan processing disruption on tyrosinase and melanin synthesis in HM3KO melanoma cells.	n-glycan	13-21	tyrosinase	Homo sapiens	47-57
17222224-3	2007	Previous studies showed that the disruption of early ER N-glycan processing by deoxynojirimycin (DNJ), an inhibitor of alpha-glucosidase, suppresses tyrosinase enzymatic activity and melanogenesis.	n-glycan	56-64	sucrase-isomaltase	Homo sapiens	119-136
17222224-3	2007	Previous studies showed that the disruption of early ER N-glycan processing by deoxynojirimycin (DNJ), an inhibitor of alpha-glucosidase, suppresses tyrosinase enzymatic activity and melanogenesis.	n-glycan	56-64	tyrosinase	Homo sapiens	149-159
17167046-5	2007	The apoptosis was inhibited by pretreatment with an N-glycan synthesis inhibitor, indicating that the expression of N-glycans in the cells is essential for galectin-9-induced apoptosis.	n-glycan	52-60	galectin 9	Homo sapiens	156-166
16917081-0	2006	Effects of N-glycan processing inhibitors on signaling events and induction of apoptosis in galectin-1-stimulated Jurkat T lymphocytes.	n-glycan	11-19	galectin 1	Homo sapiens	92-102
17263732-8	2007	We demonstrated that the loss of N-glycan on N163 caused a slight decrease in protein O-fucosyltransferase 1 activity.	n-glycan	33-41	protein O-fucosyltransferase 1	Bos taurus	78-108
17268079-4	2007	Lectin blots by Con A, LCA, PHA-E4, RCA120 or WGA revealed the presence of N-glycan in the cellular TNX and especially complex-type N-glycan in the serum TNX.	n-glycan	75-83	tenascin XB	Mus musculus	100-103
17268079-4	2007	Lectin blots by Con A, LCA, PHA-E4, RCA120 or WGA revealed the presence of N-glycan in the cellular TNX and especially complex-type N-glycan in the serum TNX.	n-glycan	75-83	tenascin XB	Mus musculus	154-157
17268079-4	2007	Lectin blots by Con A, LCA, PHA-E4, RCA120 or WGA revealed the presence of N-glycan in the cellular TNX and especially complex-type N-glycan in the serum TNX.	n-glycan	132-140	tenascin XB	Mus musculus	154-157
17121831-0	2007	Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation.	n-glycan	102-110	mannosidase, alpha, class 1A, member 2	Mus musculus	66-89
17121831-12	2007	The alpha1,2-mannosidase IB null phenotype differs from phenotypes caused by ablation of other enzymes in N-glycan biosynthesis and from other mouse gene disruptions that affect pulmonary development and function.	n-glycan	106-114	mannosidase, alpha, class 1A, member 2	Mus musculus	4-27
17177443-12	2006	This modeling study provided detailed insight into the mechanism of the GlcNAc transfer catalyzed by GnT-I, which is the first step in the conversion of high mannose oligosaccharides to complex and hybrid N-glycan structures.	n-glycan	205-213	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	101-106
17003032-0	2006	A novel alpha-helix in the first fibronectin type III repeat of the neural cell adhesion molecule is critical for N-glycan polysialylation.	n-glycan	114-122	fibronectin 1	Homo sapiens	33-44
16877748-0	2006	N-glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry.	n-glycan	0-8	intercellular adhesion molecule 1	Mus musculus	63-96
16899540-1	2006	alpha-Mannosidase IIx (MX) is an enzyme closely related to alpha-mannosidase II (MII), a key enzyme in N-glycan biosynthesis that catalyzes the first step in conversion of hybrid- to complex-type N-glycans in Golgi apparatus.	n-glycan	103-111	mannosidase 2, alpha 2	Mus musculus	0-21
16864579-0	2006	A deletion in the golgi alpha-mannosidase II gene of Caenorhabditis elegans results in unexpected non-wild-type N-glycan structures.	n-glycan	112-120	Alpha-mannosidase	Caenorhabditis elegans	24-41
16920165-5	2006	The cloned XylT and FucT cDNAs were shown to encode enzymatically active proteins, which were independently able to convert a mammalian acceptor glycoprotein into an antigen binding anti-plant N-glycan antibodies.	n-glycan	193-201	beta-1,2-xylosyltransferase	Zea mays	11-15
17067392-0	2006	Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors.	n-glycan	45-53	mesothelin	Homo sapiens	0-10
17067392-0	2006	Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors.	n-glycan	45-53	mucin 16, cell surface associated	Homo sapiens	11-16
16864579-5	2006	The analysis of the N-glycan structures of an aman-2 mutant strain demonstrates that the absence of alpha-mannosidase II activity results in a shift to structures not seen in wild-type worms (e.g. N-glycans with the composition Hex(5-7)HexNAc(2-3)Fuc(2)Me) and an accumulation of hybrid oligosaccharides.	n-glycan	20-28	Alpha-mannosidase	Caenorhabditis elegans	46-52
16912292-0	2006	Mutational pathways, resistance profile, and side effects of cyanovirin relative to human immunodeficiency virus type 1 strains with N-glycan deletions in their gp120 envelopes.	n-glycan	133-141	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	161-166
16912292-5	2006	Two mutations (i.e., at position 136 and 160) deleted a complex type N-glycan in the variable V1/V2 domain of gp120.	n-glycan	69-77	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	110-115
16585136-7	2006	Many of the N-glycan structures are identical on MUC1F and native MUC1; however, a marked difference is seen between the N-glycans on membrane-bound and secreted forms of the native molecule.	n-glycan	12-20	mucin 1, cell surface associated	Homo sapiens	49-53
16682414-2	2006	E-cadherin ectodomains 4 and 5 contain three potential N-glycan addition sites, although their significance in AJ stability is unclear.	n-glycan	55-63	cadherin 1	Canis lupus familiaris	0-10
16682414-8	2006	Removal of complex N-glycan from ectodomain 4 led to a dramatically increased interaction of E-cadherin-catenin complexes with vinculin and the actin cytoskeleton.	n-glycan	19-27	cadherin 1	Canis lupus familiaris	93-103
16682414-8	2006	Removal of complex N-glycan from ectodomain 4 led to a dramatically increased interaction of E-cadherin-catenin complexes with vinculin and the actin cytoskeleton.	n-glycan	19-27	vinculin	Canis lupus familiaris	127-135
16709668-1	2006	Mouse peptide N-glycanase (mPNGase) cleaves the N-glycan chain from misfolded glycoproteins and glycopeptides.	n-glycan	14-22	N-glycanase 1	Mus musculus	27-34
16817772-0	2006	Neutralizing antibody responses of pigs infected with natural GP5 N-glycan mutants of porcine reproductive and respiratory syndrome virus.	n-glycan	66-74	glycoprotein V platelet	Sus scrofa	62-65
16735443-5	2006	In absence of light chains, instead, aggregation occurs in smooth tubular vesicles and is controlled by N-glycan-dependent interactions with ER-Golgi intermediate compartment 53 (ERGIC-53).	n-glycan	104-112	lectin, mannose binding 1	Homo sapiens	141-177
16735443-5	2006	In absence of light chains, instead, aggregation occurs in smooth tubular vesicles and is controlled by N-glycan-dependent interactions with ER-Golgi intermediate compartment 53 (ERGIC-53).	n-glycan	104-112	lectin, mannose binding 1	Homo sapiens	179-187
16546121-8	2006	Thus, heterogeneity in minor haptoglobin isoforms was due to modifications distinct from N-glycan structure.	n-glycan	89-97	haptoglobin	Homo sapiens	29-40
16581792-3	2006	Herein we report that fibronectin fibrillogenesis and fibronectin-dependent cell spreading are deficient in Mgat5(-/-) mammary epithelial tumor cells and inhibited in Mgat5(+/+) cells by blocking Golgi N-glycan processing with swainsonine or by competitive inhibition of galectin binding.	n-glycan	202-210	fibronectin 1	Homo sapiens	22-33
16756569-2	2006	In a previous study, we demonstrated that the high mannose type of N-glycan of the envelope glycoprotein is closely related to PERV infectivity with respect to human cells.	n-glycan	67-75	endogenous retrovirus group K member 20	Homo sapiens	83-104
16638859-1	2006	PURPOSE: N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	9-42
16638859-1	2006	PURPOSE: N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	44-49
16638859-1	2006	PURPOSE: N-acetylglucosaminyltransferase V (GnT-V) is an enzyme that catalyzes beta1-6 branching of N-acetylglucosamine on asparagine (N)-linked oligosaccharides (N-glycan) of cell proteins.	n-glycan	163-171	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	79-86
16531414-0	2006	The MRH protein Erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition.	n-glycan	103-111	endoplasmic reticulum lectin 1 L homeolog	Xenopus laevis	16-24
16531414-3	2006	Erlectin (XTP3-B) is member of a protein family containing mannose 6-phosphate receptor homology (MRH-, or PRKCSH-) domains implicated in N-glycan binding.	n-glycan	138-146	endoplasmic reticulum lectin 1 L homeolog	Xenopus laevis	0-8
16531414-3	2006	Erlectin (XTP3-B) is member of a protein family containing mannose 6-phosphate receptor homology (MRH-, or PRKCSH-) domains implicated in N-glycan binding.	n-glycan	138-146	endoplasmic reticulum lectin 1 L homeolog	Xenopus laevis	10-16
16531414-9	2006	The results indicate that Erlectin functions in N-glycan recognition in the endoplasmic reticulum, suggesting that it may regulate glycoprotein traffic.	n-glycan	48-56	endoplasmic reticulum lectin 1 L homeolog	Xenopus laevis	26-34
16428802-3	2006	The assay exploits the fact that GnT VI has a strict requirement for the GlcNAcbeta1-6Manalpha1 structure for activity, when a pyridylaminated free N-glycan is used as the acceptor substrate.	n-glycan	148-156	MGAT4 family member C	Gallus gallus	33-39
16581792-3	2006	Herein we report that fibronectin fibrillogenesis and fibronectin-dependent cell spreading are deficient in Mgat5(-/-) mammary epithelial tumor cells and inhibited in Mgat5(+/+) cells by blocking Golgi N-glycan processing with swainsonine or by competitive inhibition of galectin binding.	n-glycan	202-210	fibronectin 1	Homo sapiens	54-65
16460512-5	2006	Furthermore, a detailed N-glycan analysis of two AtGMII knockout mutants revealed the predominant presence of unprocessed hybrid N-glycans.	n-glycan	24-32	golgi alpha-mannosidase II	Arabidopsis thaliana	49-55
16373354-8	2006	Our data demonstrate that Gtb1p is required for normal glycoprotein biogenesis and reveal that the final two glucose-trimming steps in N-glycan processing are mechanistically distinct.	n-glycan	135-143	Gtb1p	Saccharomyces cerevisiae S288C	26-31
16306051-0	2006	Substitution of the N-glycan function in glycosyltransferases by specific amino acids: ST3Gal-V as a model enzyme.	n-glycan	20-28	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	87-95
16306051-5	2006	Therefore, we considered whether the function in the activity that is performed in mST3Gal-V by the N-glycan could be substituted for by specific amino acid residues selected from the ST3Gal-V of other species or from related sialyltransferases (ST3Gal-I, -II, -III, and -IV), placed at or near the glycosylation sites.	n-glycan	100-108	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	83-92
16306051-5	2006	Therefore, we considered whether the function in the activity that is performed in mST3Gal-V by the N-glycan could be substituted for by specific amino acid residues selected from the ST3Gal-V of other species or from related sialyltransferases (ST3Gal-I, -II, -III, and -IV), placed at or near the glycosylation sites.	n-glycan	100-108	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	Mus musculus	84-92
16319176-7	2006	Disruption of genes involved in GPI-anchored protein concentration and N-glycan processing caused different effects on the degradation of Gas1*p and a soluble misfolded version of carboxypeptidase Y.	n-glycan	71-79	growth arrest specific 1	Homo sapiens	138-142
16339150-0	2006	The Drosophila fused lobes gene encodes an N-acetylglucosaminidase involved in N-glycan processing.	n-glycan	79-87	fused lobes	Drosophila melanogaster	15-26
17116467-3	2006	The deglycosylation reaction by PNGase brings about two major changes on substrate proteins; one is a removal of N-glycan chains, and the other is the introduction of negative charge(s) into the core peptide by converting glycosylated asparagine residue(s) into aspartic acid residue(s).	n-glycan	113-121	N-glycanase 1	Homo sapiens	32-38
16280320-1	2006	Dolichol-phosphate mannose (DPM) synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose.	n-glycan	118-126	dolichol-phosphate mannosyltransferase subunit 1	Cricetulus griseus	0-41
17113875-1	2006	Alpha-mannosidase IIx (MX) and alpha-mannosidase II (MII) are homologous enzymes whose critical roles in N-glycan processing were established in large part by analysis of the MII/MX double-knockout mouse.	n-glycan	105-113	mannosidase 2, alpha 2	Mus musculus	0-21
16327992-9	2006	In conclusion, alteration of cell surface sialylation or N-glycan expression regulates cell adhesion to galectin-1 in human malignant lymphoma.	n-glycan	57-65	galectin 1	Homo sapiens	104-114
16381065-8	2006	Thus, negative-ion MSn (n = 2, 3) spectral matching was demonstrated to be useful for the structural assignment of these four monosialylated PA N-glycan isomers.	n-glycan	144-152	moesin	Homo sapiens	19-22
16025538-0	2005	Production and N-glycan analysis of secreted human erythropoietin glycoprotein in stably transfected Drosophila S2 cells.	n-glycan	15-23	erythropoietin	Homo sapiens	51-65
16456804-1	2006	Positive- and negative-ion MSn spectra of chicken egg yolk glycopeptides binding a neutral and a sialylated N-glycan were acquired by using electrospray ionization linear ion trap time-of-flight mass spectrometry (ESI-LIT-TOFMS) and collision-induced dissociation (CID) with helium as collision gas.	n-glycan	108-116	moesin	Gallus gallus	27-30
16037488-5	2005	We also demonstrated that in galactosemia patients, transferrin N-glycan biosynthesis is restored upon dietary treatment.	n-glycan	64-72	transferrin	Homo sapiens	52-63
16037491-4	2005	Transferrin IEF (TIEF) has been used to distinguish between N-glycan assembly (type 1 profile) and processing (type 2 profile) defects.	n-glycan	60-68	transferrin	Homo sapiens	0-11
16377570-2	2005	We show that the murine GlcNAcT-IVa glycosyltransferase is required for Glut-2 residency on the beta cell surface by constructing a cell-type- and glycoprotein-specific N-glycan ligand for pancreatic lectin receptors.	n-glycan	169-177	mannoside acetylglucosaminyltransferase 4, isoenzyme A	Mus musculus	24-35
16377570-2	2005	We show that the murine GlcNAcT-IVa glycosyltransferase is required for Glut-2 residency on the beta cell surface by constructing a cell-type- and glycoprotein-specific N-glycan ligand for pancreatic lectin receptors.	n-glycan	169-177	solute carrier family 2 (facilitated glucose transporter), member 2	Mus musculus	72-78
15827987-6	2005	The oligosaccharides (N-glycan) were released from ovalbumin (glycoprotein) by PNGase F after tryptic digestion.	n-glycan	22-30	serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene	Mus musculus	51-60
16116208-8	2005	Our results suggest that core N-linked oligosaccharides on meprins are associated with the optimal enzymatic activity and that MBP is an important regulator for modulation of the localized meprin proteolytic activity via N-glycan binding.	n-glycan	221-229	myelin basic protein	Homo sapiens	127-130
16085795-1	2005	Congenital disorder of glycosylation Ia (CDGIa) is an autosomal recessive disease that is caused by mutations in the gene PMM2 encoding phosphomannomutase, an enzyme that synthesizes mannose-1-phosphate, an important intermediate for the N-glycan biosynthesis.	n-glycan	238-246	phosphomannomutase 2	Homo sapiens	122-126
16157350-7	2005	Present studies suggest that beta4Gal-T1 interacts preferentially with the 1,2-1,6-arm trisaccharide rather than with the 1,2-1,3-arm or 1,4-1,3-arm of a bi- or tri-antennary oligosaccharide chain of N-glycan.	n-glycan	200-208	beta-1,4-galactosyltransferase 1	Homo sapiens	29-40
16159142-0	2005	Structural analysis of an N-glycan with "beta1-4 bisecting branch" from human serum IgG by negative-ion MSn spectral matching and exoglycosidase digestion.	n-glycan	26-34	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	41-48
16159142-0	2005	Structural analysis of an N-glycan with "beta1-4 bisecting branch" from human serum IgG by negative-ion MSn spectral matching and exoglycosidase digestion.	n-glycan	26-34	moesin	Homo sapiens	104-107
16159142-1	2005	A novel N-linked oligosaccharide (N-glycan) with "beta1-4 bisecting branch (galactose beta1-4 bisecting N-acetylglucosamine)" was found in human serum IgG.	n-glycan	34-42	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	50-57
16159142-1	2005	A novel N-linked oligosaccharide (N-glycan) with "beta1-4 bisecting branch (galactose beta1-4 bisecting N-acetylglucosamine)" was found in human serum IgG.	n-glycan	34-42	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	86-93
16159142-3	2005	For confirmation, the novel N-glycan was synthesized by using an expected standard N-glycan (acceptor), UDP-galactose (donor), and beta1-4 galactosyltransferase.	n-glycan	28-36	eukaryotic translation elongation factor 1 beta 2 pseudogene 2	Homo sapiens	131-138
15858074-7	2005	Notably, ST3Gal I and III and ST6GalNAc VI are involved in the synthesis of the alpha2,3- and alpha2,6-Sia glycotopes on O-glycan chains and possibly on gangliosides, whereas ST6Gal I is specific for N-glycan chains.	n-glycan	200-208	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	Mus musculus	9-25
15858074-7	2005	Notably, ST3Gal I and III and ST6GalNAc VI are involved in the synthesis of the alpha2,3- and alpha2,6-Sia glycotopes on O-glycan chains and possibly on gangliosides, whereas ST6Gal I is specific for N-glycan chains.	n-glycan	200-208	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	Mus musculus	30-42
15858074-7	2005	Notably, ST3Gal I and III and ST6GalNAc VI are involved in the synthesis of the alpha2,3- and alpha2,6-Sia glycotopes on O-glycan chains and possibly on gangliosides, whereas ST6Gal I is specific for N-glycan chains.	n-glycan	200-208	beta galactoside alpha 2,6 sialyltransferase 1	Mus musculus	175-183
15604092-3	2005	Here we report the N-glycan pattern and N-glycosylation sites of the porcine ZP glycoprotein ZPA of an immature oocyte population as determined by a mass spectrometric approach.	n-glycan	19-27	zona pellucida glycoprotein 2	Homo sapiens	93-96
15919930-10	2005	Recombination of the mutated gp160 genes of the strains resistant to CV-N or ConA into a wild-type background fully reproduced the (cross-)resistance profiles of the originally selected strains, pointing to the impact of the N-glycan mutations on the phenotypic resistance profiles of both selected strains.	n-glycan	225-233	glutamyl aminopeptidase	Homo sapiens	29-34
15912449-3	2005	On the other hand, terminal beta(1,4)-galactose, a sugar common on N-glycans of pharmaceutically relevant proteins, e.g., antibodies, is missing in plant N-glycan structures.	n-glycan	67-75	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	28-36
15537386-6	2005	Expression of Asn144 rabbit GnTI in cgl plants could partially restore complex N-glycan formation.	n-glycan	79-87	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Oryctolagus cuniculus	28-32
15823038-7	2005	Since previous studies have shown that N-glycan-bound calnexin/calreticulin are also capable of recruiting ERp57, our results suggest that N-linked glycosylation and RAP can independently and cooperatively recruit oxidoreductases to facilitate protein folding and proper disulfide bond formation.	n-glycan	39-47	calnexin	Homo sapiens	54-62
15823038-7	2005	Since previous studies have shown that N-glycan-bound calnexin/calreticulin are also capable of recruiting ERp57, our results suggest that N-linked glycosylation and RAP can independently and cooperatively recruit oxidoreductases to facilitate protein folding and proper disulfide bond formation.	n-glycan	39-47	calreticulin	Homo sapiens	63-75
15823038-7	2005	Since previous studies have shown that N-glycan-bound calnexin/calreticulin are also capable of recruiting ERp57, our results suggest that N-linked glycosylation and RAP can independently and cooperatively recruit oxidoreductases to facilitate protein folding and proper disulfide bond formation.	n-glycan	39-47	protein disulfide isomerase family A member 3	Homo sapiens	107-112
15823038-7	2005	Since previous studies have shown that N-glycan-bound calnexin/calreticulin are also capable of recruiting ERp57, our results suggest that N-linked glycosylation and RAP can independently and cooperatively recruit oxidoreductases to facilitate protein folding and proper disulfide bond formation.	n-glycan	39-47	LDL receptor related protein associated protein 1	Homo sapiens	166-169
15537386-7	2005	These results indicate that the complete deficiency of GnTI activity in cgl plants is mainly due to the additional N-glycan, which appears to interfere with the proper folding of the enzyme.	n-glycan	115-123	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	55-59
15707965-3	2005	TRP-2 N-glycan processing is interrupted by Mon between ER and trans-Golgi, whereas this process continues for TRP-1.	n-glycan	6-14	tRNA proline 2	Mus musculus	0-5
15657036-5	2005	Intracellular FGE contains a high mannose type N-glycan, which is processed to the complex type in secreted FGE.	n-glycan	47-55	sulfatase modifying factor 1	Homo sapiens	14-17
15657036-5	2005	Intracellular FGE contains a high mannose type N-glycan, which is processed to the complex type in secreted FGE.	n-glycan	47-55	sulfatase modifying factor 1	Homo sapiens	108-111
15767436-0	2005	Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan.	n-glycan	184-192	C-C motif chemokine receptor 5	Homo sapiens	69-73
15767436-0	2005	Variants of human immunodeficiency virus type 1 that efficiently use CCR5 lacking the tyrosine-sulfated amino terminus have adaptive mutations in gp120, including loss of a functional N-glycan.	n-glycan	184-192	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	146-151
15804604-4	2005	This chapter discusses two of the steps that regulate the abundance of such N-glycan structures, including glycoprotein deglucosylation (by glucosidase II) and reglucosylation (by the UDP-Glc:glycoprotein glucosyltransferase), as well as an overview of methods to evaluate the N-glycans prevalent during glycoprotein biogenesis in the ER.	n-glycan	76-84	UDP-glucose glycoprotein glucosyltransferase 1	Homo sapiens	184-224
15804608-4	2005	The deglycosylation reaction by PNGase brings about two major changes on substrate the peptide; one is removal of the N-glycan chain and the other is the introduction of a negative charge into the core peptide by converting the glycosylated asparagine residue(s) into an aspartic acid residue(s).	n-glycan	118-126	N-glycanase 1	Homo sapiens	32-38
15767436-6	2005	Consistent with this interpretation, loss of the V4 N-glycan at position N403 also enhanced HIV-1 use of a different low-affinity CCR5 coreceptor with a mutation in extracellular loop 2 (ECL2) [i.e., CCR5(G163R)], whereas the double mutant CCR5(Delta18,G163R) was inactive.	n-glycan	52-60	C-C motif chemokine receptor 5	Homo sapiens	130-134
15767436-6	2005	Consistent with this interpretation, loss of the V4 N-glycan at position N403 also enhanced HIV-1 use of a different low-affinity CCR5 coreceptor with a mutation in extracellular loop 2 (ECL2) [i.e., CCR5(G163R)], whereas the double mutant CCR5(Delta18,G163R) was inactive.	n-glycan	52-60	C-C motif chemokine receptor 5	Homo sapiens	200-204
15767436-6	2005	Consistent with this interpretation, loss of the V4 N-glycan at position N403 also enhanced HIV-1 use of a different low-affinity CCR5 coreceptor with a mutation in extracellular loop 2 (ECL2) [i.e., CCR5(G163R)], whereas the double mutant CCR5(Delta18,G163R) was inactive.	n-glycan	52-60	C-C motif chemokine receptor 5	Homo sapiens	200-204
15767436-7	2005	We conclude that loss of the N-glycan at position N403 helps to convert the HIV-1 envelope into a hair-trigger form that no longer requires strong interactions with both the CCR5 amino terminus and ECL2 but efficiently uses either site alone.	n-glycan	29-37	C-C motif chemokine receptor 5	Homo sapiens	174-178
15686882-2	2005	The synthesis consists of two steps: the solid phase synthesis of GlcNAc-CD52 and the transfer of a high-mannose type or complex type N-glycan from Man(9)GlcNAc(2) Asn or a sialglycopeptide to the GlcNAc-CD52, under the catalysis of the endo-beta-N-acetylglucosaminidases from Arthrobacter (Endo-A) and Mucor hiemalis (Endo-M), respectively.	n-glycan	134-142	CD52 molecule	Homo sapiens	204-208
15317738-10	2005	To verify these data, MALDI-TOF MS analysis after stepwise exoglycosidase digestion of the CEACAM1 N-glycan mixture was performed.	n-glycan	99-107	CEA cell adhesion molecule 1	Homo sapiens	91-98
15620693-3	2005	Beta3Gn-T8 transfers GlcNAc to the non-reducing terminus of the Galbeta1-4GlcNAc of tetraantennary N-glycan in vitro.	n-glycan	99-107	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1	Homo sapiens	0-10
15713887-0	2005	Substrate specificity and molecular cloning of the lily endo-beta-mannosidase acting on N-glycan.	n-glycan	88-96	mannosidase beta	Homo sapiens	61-77
15605233-0	2005	Characterization of membrane N-glycan binding sites of lysozyme for cardiac depression in sepsis.	n-glycan	29-37	lysozyme	Homo sapiens	55-63
15605233-4	2005	The objectives of the present study were: 1) to determine whether the binding of lysozyme is reversible; 2) to assess the N-glycan structure to which lysozyme binds; 3) to examine whether nonenzymatic proteins, termed lectins, with a binding specificity similar to that of lysozyme could also cause depression; and 4) to assess whether the membrane to which lysozyme binds is affected by the enzymes protease type XIV and collagenase A, that are used to prepare single cell myocyte experiments.	n-glycan	122-130	lysozyme	Homo sapiens	150-158
15605233-4	2005	The objectives of the present study were: 1) to determine whether the binding of lysozyme is reversible; 2) to assess the N-glycan structure to which lysozyme binds; 3) to examine whether nonenzymatic proteins, termed lectins, with a binding specificity similar to that of lysozyme could also cause depression; and 4) to assess whether the membrane to which lysozyme binds is affected by the enzymes protease type XIV and collagenase A, that are used to prepare single cell myocyte experiments.	n-glycan	122-130	lysozyme	Homo sapiens	150-158
15605233-4	2005	The objectives of the present study were: 1) to determine whether the binding of lysozyme is reversible; 2) to assess the N-glycan structure to which lysozyme binds; 3) to examine whether nonenzymatic proteins, termed lectins, with a binding specificity similar to that of lysozyme could also cause depression; and 4) to assess whether the membrane to which lysozyme binds is affected by the enzymes protease type XIV and collagenase A, that are used to prepare single cell myocyte experiments.	n-glycan	122-130	lysozyme	Homo sapiens	150-158
15538974-6	2004	Computer modeling showed that core fucosylation on E-cadherin could significantly impair three-dimensional conformation of N-glycan on E-cadherin and produce conformational asymmetry so as to suppress the function of E-cadherin.	n-glycan	123-131	cadherin 1	Homo sapiens	135-145
16233760-3	2005	Moreover, AGP added to medium was found to maintain the number of viable hepatocytes for as long as 6 d. The hepatoprotective effect of AGP was lost by removing sialic acid groups at the N-glycan chain terminal of AGP.	n-glycan	187-195	orosomucoid 1	Rattus norvegicus	10-13
16233760-3	2005	Moreover, AGP added to medium was found to maintain the number of viable hepatocytes for as long as 6 d. The hepatoprotective effect of AGP was lost by removing sialic acid groups at the N-glycan chain terminal of AGP.	n-glycan	187-195	orosomucoid 1	Rattus norvegicus	136-139
16233760-3	2005	Moreover, AGP added to medium was found to maintain the number of viable hepatocytes for as long as 6 d. The hepatoprotective effect of AGP was lost by removing sialic acid groups at the N-glycan chain terminal of AGP.	n-glycan	187-195	orosomucoid 1	Rattus norvegicus	136-139
16233760-4	2005	It is shown that the complete form of N-glycan chain is needed for the hepatoprotectivity of AGP.	n-glycan	38-46	orosomucoid 1	Rattus norvegicus	93-96
15585841-4	2004	In this study we examined the role of beta1,6GlcNAc N-glycan expression in Th1/Th2 cytokine production and differentiation.	n-glycan	52-60	negative elongation factor complex member C/D, Th1l	Mus musculus	75-78
15610311-1	2004	BACKGROUND AND AIM: UDP-N-acetylglucosamine: alpha-D-mannoside beta-1,4 N-acetylglucosaminyltransferase III (GnT-III) is a key enzyme in N-glycan biosynthesis.	n-glycan	137-145	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	109-116
15535969-0	2004	LacdiNAc (GalNAcbeta1-4GlcNAc) is a major motif in N-glycan structures of the chicken eggshell protein ovocleidin-116.	n-glycan	51-59	matrix extracellular phosphoglycoprotein	Gallus gallus	103-117
15538974-6	2004	Computer modeling showed that core fucosylation on E-cadherin could significantly impair three-dimensional conformation of N-glycan on E-cadherin and produce conformational asymmetry so as to suppress the function of E-cadherin.	n-glycan	123-131	cadherin 1	Homo sapiens	51-61
15538974-6	2004	Computer modeling showed that core fucosylation on E-cadherin could significantly impair three-dimensional conformation of N-glycan on E-cadherin and produce conformational asymmetry so as to suppress the function of E-cadherin.	n-glycan	123-131	cadherin 1	Homo sapiens	135-145
15700237-10	2005	Thereby, the main glycoforms of EPO-alpha, EPO-beta and NESP could be characterised based on their N-glycan composition.	n-glycan	99-107	GNAS complex locus	Homo sapiens	56-60
15585841-4	2004	In this study we examined the role of beta1,6GlcNAc N-glycan expression in Th1/Th2 cytokine production and differentiation.	n-glycan	52-60	heart and neural crest derivatives expressed 2	Mus musculus	79-82
14998999-8	2004	These findings suggest that the modification of N-glycan of integrin by GnT-III inhibits its ligand binding ability, subsequently leading to the down-regulation of integrin-mediated signaling.	n-glycan	48-56	mannoside acetylglucosaminyltransferase 3	Mus musculus	72-79
15450188-6	2004	We identify DER7 as the gene encoding N-glycan-processing alpha-glucosidase I (EC 3.2.1.106) of the ER and demonstrate that its inactivity, due to a substitution of the conserved glycine residue at position 725 by arginine (G725R) in the der7-1 mutant, leads to ER-stress.	n-glycan	38-46	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	12-16
15450188-6	2004	We identify DER7 as the gene encoding N-glycan-processing alpha-glucosidase I (EC 3.2.1.106) of the ER and demonstrate that its inactivity, due to a substitution of the conserved glycine residue at position 725 by arginine (G725R) in the der7-1 mutant, leads to ER-stress.	n-glycan	38-46	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	238-242
15044398-5	2004	Nevertheless, a requirement for hybrid and complex N-glycan branching exists in embryonic development and postnatal function among mice and humans inheriting defective Mgat1 or Mgat2 alleles.	n-glycan	51-59	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	168-173
15044398-5	2004	Nevertheless, a requirement for hybrid and complex N-glycan branching exists in embryonic development and postnatal function among mice and humans inheriting defective Mgat1 or Mgat2 alleles.	n-glycan	51-59	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	177-182
15044398-11	2004	Unexpectedly, neuronal Mgat2 deletion resulting in the loss of complex but not hybrid N-glycan branching was well tolerated without phenotypic markers of neuronal or locomotor dysfunction.	n-glycan	86-94	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	23-28
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	n-glycan	130-138	mannoside acetylglucosaminyltransferase 5	Mus musculus	17-58
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	n-glycan	130-138	mannoside acetylglucosaminyltransferase 5	Mus musculus	60-65
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	n-glycan	130-138	lectin, galactose binding, soluble 3	Mus musculus	195-205
15459394-1	2004	The Golgi enzyme beta1,6 N-acetylglucosaminyltransferase V (Mgat5) is up-regulated in carcinomas and promotes the substitution of N-glycan with poly N-acetyllactosamine, the preferred ligand for galectin-3 (Gal-3).	n-glycan	130-138	lectin, galactose binding, soluble 3	Mus musculus	207-212
15228383-1	2004	We have previously reported, from the nematode worm Caenor-habditis elegans, three genes (gly-12, gly-13 and gly-14) encoding enzymically active UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid, paucimannose and complex N-glycan synthesis.	n-glycan	300-308	GLYcosylation related	Caenorhabditis elegans	90-96
15228383-1	2004	We have previously reported, from the nematode worm Caenor-habditis elegans, three genes (gly-12, gly-13 and gly-14) encoding enzymically active UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid, paucimannose and complex N-glycan synthesis.	n-glycan	300-308	Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Caenorhabditis elegans	98-104
15228383-1	2004	We have previously reported, from the nematode worm Caenor-habditis elegans, three genes (gly-12, gly-13 and gly-14) encoding enzymically active UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid, paucimannose and complex N-glycan synthesis.	n-glycan	300-308	GLYcosylation related	Caenorhabditis elegans	109-115
15247239-0	2004	Endo-beta-mannosidase, a plant enzyme acting on N-glycan: purification, molecular cloning, and characterization.	n-glycan	48-56	mannosidase beta	Homo sapiens	5-21
15201278-4	2004	Here we showed that N-glycan structures of sICAM-1 influence its ability to induce MIP-2 production.	n-glycan	20-28	chemokine (C-X-C motif) ligand 2	Mus musculus	83-88
15044389-1	2004	We performed a detailed investigation of N-glycan structures on BM-40 purified from different sources including human bone, human platelets, mouse Engelbreth-Holm-Swarm (EHS) tumor, and human BM-40 recombinantly expressed in 293 and osteosarcoma cells.	n-glycan	41-49	secreted protein acidic and cysteine rich	Homo sapiens	64-69
15084511-2	2004	We used mass spectrometry techniques combined with exoglycosidase digestions of recombinant human GnT-V expressed in CHO cells, to identify its N-glycan structures and their sites of expression.	n-glycan	144-152	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	98-103
14722111-11	2004	Although the human ST3Gal I has four N-glycan attachment sites in its catalytic domain that are potentially glycosylated, none of them was shown to be necessary for enzyme activity.	n-glycan	37-45	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	Homo sapiens	19-27
15047148-2	2004	Even though nearly 50% of the molecular mass of CD28 is N-glycan, the physiological significance of CD28 glycosylation is at present unknown.	n-glycan	56-64	CD28 molecule	Homo sapiens	48-52
15228095-8	2004	These results reveal that cell surface complex-type N-glycans with GlcNAc beta1,6 branch are more effective than those without this branch in the cell adhesion to HUVEC and cell migration, but N-glycan without GlcNAc beta1,6-branch is the better one in mediating the cell adhesion to Fn.	n-glycan	52-60	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1	Homo sapiens	74-79
15228095-8	2004	These results reveal that cell surface complex-type N-glycans with GlcNAc beta1,6 branch are more effective than those without this branch in the cell adhesion to HUVEC and cell migration, but N-glycan without GlcNAc beta1,6-branch is the better one in mediating the cell adhesion to Fn.	n-glycan	52-60	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1	Homo sapiens	217-222
14520005-0	2003	350-kDa royal jelly glycoprotein (apisin), which stimulates proliferation of human monocytes, bears the beta1-3galactosylated N-glycan: analysis of the N-glycosylation site.	n-glycan	126-134	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	104-111
14996906-5	2004	The AE1 N-glycan was processed to a complex form.	n-glycan	8-16	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	4-7
14576170-6	2004	Lectin blot analysis confirmed that EGFR from wild-type GnT-III transfectants had been modified by bisecting GlcNAc in its N-glycan structures.	n-glycan	123-131	epidermal growth factor receptor	Rattus norvegicus	36-40
14576170-6	2004	Lectin blot analysis confirmed that EGFR from wild-type GnT-III transfectants had been modified by bisecting GlcNAc in its N-glycan structures.	n-glycan	123-131	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	56-63
14706853-3	2004	Moreover, we found that among the other five beta3Gn-Ts and i antigen-producing beta3Gn-T (iGn-T), beta3Gn-T2 and iGn-T act well on L2L2, although these specific activities were lower than those for a tetraantennary N-glycan.	n-glycan	216-224	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	99-109
15669674-2	2004	CDG Ie is caused by a deficiency of dolichol-phosphate-mannose synthase 1 (DPM1), an enzyme involved in N-glycan assembly in the endoplasmic reticulum.	n-glycan	104-112	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	0-6
15669674-2	2004	CDG Ie is caused by a deficiency of dolichol-phosphate-mannose synthase 1 (DPM1), an enzyme involved in N-glycan assembly in the endoplasmic reticulum.	n-glycan	104-112	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	36-73
15669674-2	2004	CDG Ie is caused by a deficiency of dolichol-phosphate-mannose synthase 1 (DPM1), an enzyme involved in N-glycan assembly in the endoplasmic reticulum.	n-glycan	104-112	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	75-79
14568956-6	2003	We demonstrated that plasma C1INH does express sialyl Lewis(x)-related moieties on its N-glycan as detected using mAb HECA-452 and CSLEX1.	n-glycan	87-95	serpin family G member 1	Homo sapiens	28-33
14640982-5	2004	The rate of N-glycan conversion from high-mannose into complex form in a glycosylation mutant (N555) of AE1 C843A, and thus the rate of trafficking from the endoplasmic reticulum to the Golgi, were comparable with that of AE1 (N555).	n-glycan	12-20	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	104-107
14640982-5	2004	The rate of N-glycan conversion from high-mannose into complex form in a glycosylation mutant (N555) of AE1 C843A, and thus the rate of trafficking from the endoplasmic reticulum to the Golgi, were comparable with that of AE1 (N555).	n-glycan	12-20	solute carrier family 4 member 1 (Diego blood group)	Homo sapiens	222-225
15750791-5	2004	These studies revealed a possible regulatory role for the N-glycan on Edg-1/S1P1 in the dynamics of the receptor, such as its lateral and internal movements within the membrane, in ligand-stimulated mammalian cells.	n-glycan	58-66	sphingosine-1-phosphate receptor 1	Homo sapiens	70-75
15750791-5	2004	These studies revealed a possible regulatory role for the N-glycan on Edg-1/S1P1 in the dynamics of the receptor, such as its lateral and internal movements within the membrane, in ligand-stimulated mammalian cells.	n-glycan	58-66	sphingosine-1-phosphate receptor 1	Homo sapiens	76-80
15287381-2	2004	We examined the role of an N-glycan located in the V3 loop of HIV-1 (N306) that is known to modulate the immunogenicity of gp120.	n-glycan	27-35	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	123-128
12941944-7	2003	Namely, the new GnT (designated as GnT-IX) has beta1,6GnT activity not only to the alpha1,6-linked mannose arm but also to the alpha1,3-linked mannose arm of N-glycan, forming a unique structure that has not been reported to date.	n-glycan	158-166	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	16-19
12941944-7	2003	Namely, the new GnT (designated as GnT-IX) has beta1,6GnT activity not only to the alpha1,6-linked mannose arm but also to the alpha1,3-linked mannose arm of N-glycan, forming a unique structure that has not been reported to date.	n-glycan	158-166	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	35-41
12851399-3	2003	Inhibition of its secretion by brefeldin A and identification of an N-glycan on the secreted form confirmed that FGF-16 is secreted by means of the endoplasmic reticulum and Golgi apparatus, as are secreted proteins having a conventional cleavable signal sequence.	n-glycan	68-76	fibroblast growth factor 16	Homo sapiens	113-119
12744721-9	2003	To our knowledge this report is the first demonstration that a specific N-glycan plays a definitive role in mucin dimer formation.	n-glycan	72-80	solute carrier family 13 member 2	Rattus norvegicus	108-113
12941910-10	2003	The removal of specific N-glycan attachment sites from V1 and V2 led to increased sensitivity to neutralization by antibodies recognizing epitopes from both within and outside of the V1-V2 sequence.	n-glycan	24-32	immunoglobulin kappa variable 1-5	Homo sapiens	55-64
12719423-0	2003	The inhibition of early N-glycan processing targets TRP-2 to degradation in B16 melanoma cells.	n-glycan	24-32	dopachrome tautomerase	Mus musculus	52-57
14628453-0	2003	[Characterization of N-glycan mapping of bioengineering recombinant erythropoietin by capillary electrophoresis with laser-induced fluorescence].	n-glycan	21-29	erythropoietin	Homo sapiens	68-82
14628453-5	2003	The relationship between N-glycans and bioactivity of EPO was investigated on the basis of N-glycan mapping spectra.	n-glycan	25-33	erythropoietin	Homo sapiens	54-57
14628453-10	2003	In case of asialyated N-glycan mapping, the retention time of each oligosaccharide delayed greatly, and most importantly, the resulted sialic acid peak can be used as a quantitative standard to determine sialic acid content in N-glycans of EPO.	n-glycan	22-30	erythropoietin	Homo sapiens	240-243
14628453-11	2003	In addition, the difference of N-glycan mapping was observed when the in vivo biological activity of EPO was different.	n-glycan	31-39	erythropoietin	Homo sapiens	101-104
14628453-12	2003	CONCLUSION: The approach in this article for determining N-glycan mapping can be applied to determine the source of EPO and the difference between each batch.	n-glycan	57-65	erythropoietin	Homo sapiens	116-119
12787029-0	2003	N-Glycan structures of squid rhodopsin.	n-glycan	0-8	rhodopsin	Homo sapiens	29-38
12672704-0	2003	N-glycan structures of human transferrin produced by Lymantria dispar (gypsy moth) cells using the LdMNPV expression system.	n-glycan	0-8	transferrin	Homo sapiens	29-40
12672704-1	2003	N-glycan structures of recombinant human serum transferrin (hTf) expressed by Lymantria dispar (gypsy moth) 652Y cells were determined.	n-glycan	0-8	transferrin	Homo sapiens	47-58
12603202-1	2003	We have previously reported three Caenorhabditis elegans genes ( gly-12, gly-13 and gly-14 ) encoding UDP- N -acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2- N -acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid and complex N-glycan synthesis.	n-glycan	247-255	GLYcosylation related	Caenorhabditis elegans	65-71
12626401-5	2003	The serum component(s) supporting N-glycan sialylation by Sfbeta4GalT/ST6 cells is relatively large-it was not removed by dialysis in a 50,000-molecular-weight cutoff membrane.	n-glycan	34-42	CD82 molecule	Homo sapiens	70-73
12626401-6	2003	Serum-free media supplemented with purified fetuin but not asialofetuin supported N-glycan sialylation by Sfbeta4GalT/ST6 cells.	n-glycan	82-90	CD82 molecule	Homo sapiens	118-121
12603202-1	2003	We have previously reported three Caenorhabditis elegans genes ( gly-12, gly-13 and gly-14 ) encoding UDP- N -acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2- N -acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid and complex N-glycan synthesis.	n-glycan	247-255	Putative alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Caenorhabditis elegans	73-79
12603202-1	2003	We have previously reported three Caenorhabditis elegans genes ( gly-12, gly-13 and gly-14 ) encoding UDP- N -acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2- N -acetylglucosaminyltransferase I (GnT I), an enzyme essential for hybrid and complex N-glycan synthesis.	n-glycan	247-255	GLYcosylation related	Caenorhabditis elegans	84-90
12603202-6	2003	The beta- N -acetylglucosaminidase removes terminal N -acetyl-D-glucosamine from the GlcNAcbeta1, 2Manalpha1,3Manbeta- arm of Manalpha1,6(GlcNAcbeta1,2Manalpha1,3) Manbeta1,4GlcNAcbeta1,4GlcNAc-R to produce paucimannose Man(3)GlcNAc(2) N-glycan.	n-glycan	236-244	O-GlcNAcase	Homo sapiens	4-34
12716378-8	2003	It was concluded that the tetrasialylated tetra-antennary N-glycan content of EPO is a major determinant for its in vivo biological activity in the mouse.	n-glycan	58-66	erythropoietin	Homo sapiens	78-81
12626416-3	2003	A method was also developed for r-hCG that permits the complete resolution of the N-glycan from the O-glycan species.	n-glycan	82-90	Rh family C glycoprotein	Homo sapiens	32-37
12626389-5	2003	In the CDG-Ia subgroup, the extent of the serum N-glycome changes correlates with the aberration of the serum transferrin isoelectric focusing pattern, which measures the severity of the lack of entire N-glycan chains (primary consequence of CDG-I) in the liver and is the standard diagnostic test for this category of inherited diseases.	n-glycan	202-210	transferrin	Homo sapiens	110-121
12765789-7	2003	Both ST8Sia II and IV can transfer multiple alpha 2,8-linked sialic acid residues to an acceptor N-glycan containing a NeuNAc alpha 2-->3 (or 6) Gal beta 1-->4GlcNAc beta 1-->R structure without participation of other enzymes.	n-glycan	97-105	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	Homo sapiens	5-14
12417412-7	2002	Analysis of N-glycan structures in the kidneys of Mgat2-null mice showed a novel bisected hybrid N-glycan structure in which the bisecting GlcNAc residue was substituted with a beta1,4-linked galactose or the Lewis(x) structure.	n-glycan	12-20	mannoside acetylglucosaminyltransferase 2	Mus musculus	50-55
12417426-2	2002	UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (GlcNAc-TV or Mgat5) produces N-glycan intermediates that are elongated with poly N-acetyllactosamine to create ligands for the galectin family of mammalian lectins.	n-glycan	116-124	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	44-85
12417411-3	2002	GnT I adds a GlcNAc residue in beta1,2 glycosidic linkage to the Man(alpha)1,3 arm of the N-glycan core to initiate the biosynthesis of hybrid and complex N-glycans.	n-glycan	90-98	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-5
12417412-7	2002	Analysis of N-glycan structures in the kidneys of Mgat2-null mice showed a novel bisected hybrid N-glycan structure in which the bisecting GlcNAc residue was substituted with a beta1,4-linked galactose or the Lewis(x) structure.	n-glycan	97-105	mannoside acetylglucosaminyltransferase 2	Mus musculus	50-55
12417411-3	2002	GnT I adds a GlcNAc residue in beta1,2 glycosidic linkage to the Man(alpha)1,3 arm of the N-glycan core to initiate the biosynthesis of hybrid and complex N-glycans.	n-glycan	90-98	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	31-38
12417426-2	2002	UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (GlcNAc-TV or Mgat5) produces N-glycan intermediates that are elongated with poly N-acetyllactosamine to create ligands for the galectin family of mammalian lectins.	n-glycan	116-124	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	87-96
12417426-2	2002	UDP-N-acetylglucosamine:alpha-6-D-mannoside beta1,6 N-acetylglucosaminyltransferase V (GlcNAc-TV or Mgat5) produces N-glycan intermediates that are elongated with poly N-acetyllactosamine to create ligands for the galectin family of mammalian lectins.	n-glycan	116-124	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	100-105
12417422-1	2002	Alpha-mannosidase IIx (MX) is an enzyme closely related to the Golgi N-glycan processing enzyme alpha-mannosidase II (MII).	n-glycan	69-77	mannosidase 2, alpha 2	Mus musculus	0-21
12370423-5	2002	Analysis of the N-glycan in rhodopsin expressed by the HEK293S GnTI(-) stable cell line showed it to be Man(5)GlcNAc(2).	n-glycan	16-24	rhodopsin	Homo sapiens	28-37
12491101-7	2002	The PRRSV GP5 epitope is associated with an N-glycan that is conserved in both PRRSV genotypes and all LDV isolates.	n-glycan	44-52	glycoprotein V platelet	Sus scrofa	10-13
12370423-5	2002	Analysis of the N-glycan in rhodopsin expressed by the HEK293S GnTI(-) stable cell line showed it to be Man(5)GlcNAc(2).	n-glycan	16-24	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	63-67
11964163-11	2002	This study provides evidence that glycan loading, together with N-glycan terminal processing and enzyme subunit oligomerization, operate in a hierarchical and concerted manner in determining the pharmacokinetic characteristics of AChE.	n-glycan	64-72	acetylcholinesterase (Cartwright blood group)	Homo sapiens	230-234
12140560-2	2002	Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex.	n-glycan	20-28	S-phase kinase associated protein 1	Homo sapiens	71-75
12140560-2	2002	Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex.	n-glycan	20-28	cullin 1	Homo sapiens	76-83
12140560-2	2002	Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex.	n-glycan	20-28	F-box protein 2	Homo sapiens	84-88
12140560-2	2002	Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex.	n-glycan	20-28	ring-box 1	Homo sapiens	89-93
12140560-2	2002	Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex.	n-glycan	20-28	KIT ligand	Homo sapiens	95-98
12140560-2	2002	Here we report that N-glycan serves as a signal for degradation by the Skp1-Cullin1-Fbx2-Roc1 (SCF(Fbx2)) ubiquitin ligase complex.	n-glycan	20-28	F-box protein 2	Homo sapiens	99-103
12093361-3	2002	The isoelectric focusing pattern of the patient"s serum transferrin showed the partial loss of complete N-glycan side chains.	n-glycan	104-112	transferrin	Homo sapiens	56-67
11741890-4	2002	We hypothesized that this predominance might be due to insect-specific, Golgi-associated beta-N-acetylglucosaminidase (GlcNAcase)-mediated removal of N-acetylglucosamine residues from the precursor N-glycan, thereby preventing its galactosylation and terminal sialylation.	n-glycan	198-206	O-GlcNAcase	Homo sapiens	89-117
11588155-5	2001	The N-glycan composition of apoB100 derived from five LDL subpopulations (LDL1, d = 1.018-1.023; LDL2, d = 1.023-1.030; LDL3, d = 1.030-1.040; LDL4, d = 1.040-1.051; LDL5, d = 1.051-1.065 g/ml) did not vary in normolipidemic or hypercholesterolemic subjects.	n-glycan	4-12	apolipoprotein B	Homo sapiens	28-35
11844490-0	2002	A facile regio- and stereoselective synthesis of mannose octasaccharide of the N-glycan in human CD2 and mannose hexasaccharide antigenic factor 13b.	n-glycan	79-87	CD2 molecule	Homo sapiens	97-100
11859268-12	2002	Whether an in vitro degradation of the transferrin N-glycan chains causes the CDT increase should be evaluated by isoelectric focusing of the transferrin isoforms in a further study.	n-glycan	51-59	transferrin	Homo sapiens	39-50
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	43-51	nuclear receptor subfamily 0 group B member 2	Homo sapiens	39-42
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	43-51	nuclear receptor subfamily 0 group B member 2	Homo sapiens	141-144
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	43-51	N-acylsphingosine amidohydrolase 1	Homo sapiens	149-152
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	84-92	nuclear receptor subfamily 0 group B member 2	Homo sapiens	39-42
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	84-92	nuclear receptor subfamily 0 group B member 2	Homo sapiens	141-144
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	84-92	N-acylsphingosine amidohydrolase 1	Homo sapiens	149-152
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	84-92	nuclear receptor subfamily 0 group B member 2	Homo sapiens	39-42
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	84-92	nuclear receptor subfamily 0 group B member 2	Homo sapiens	141-144
12652078-6	2002	Sequential deglycosylation of the four sHp N-glycan chains caused a 3 kDa shift per N-glycan removed suggesting the 3 kDa difference between sHp and pHp may be one N-glycan chain.	n-glycan	84-92	N-acylsphingosine amidohydrolase 1	Homo sapiens	149-152
11805078-10	2001	Unexpectedly, analyses of N-glycan structures in Mgat2-null mice revealed a novel oligosaccharide branch on the "bisecting" N-acetylglucosamine.	n-glycan	26-34	mannoside acetylglucosaminyltransferase 2	Mus musculus	49-54
11785762-2	2001	Observations of mice carrying mutations in glycosyltransferase genes imply that N-glycan structures regulate T-cell receptor clustering and hence sensitivity to agonists.	n-glycan	80-88	protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2	Mus musculus	43-62
11588155-8	2001	These data provide a novel explanation for the apparent deficiency of sialic acid in small dense LDL and indicate that the global apoB100 N-glycan composition is invariable in the patient groups studied.	n-glycan	138-146	apolipoprotein B	Homo sapiens	130-137
11469797-0	2001	The widespread effect of beta 1,4-galactosyltransferase on N-glycan processing.	n-glycan	59-67	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Mus musculus	25-55
11559557-4	2001	And Galbeta1,3(4)GlcNAc alpha2,3-sialyltransferase (ST3Gal III) transfectants were made to increase further the expression of cell-surface, N-glycan, alpha2,3-linked sialic acids.	n-glycan	140-148	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	Homo sapiens	4-50
11559557-4	2001	And Galbeta1,3(4)GlcNAc alpha2,3-sialyltransferase (ST3Gal III) transfectants were made to increase further the expression of cell-surface, N-glycan, alpha2,3-linked sialic acids.	n-glycan	140-148	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	Homo sapiens	52-62
11469797-6	2001	The results showed that beta 1,4-GalT widely affects N-glycan processing by competing with GnT-IV, GnT-V, and alpha-mannosidase II in cells and also by some other mechanisms that suppress the conversion of high-mannose-type sugar chains to the hybrid type.	n-glycan	53-61	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	Mus musculus	24-37
11469797-6	2001	The results showed that beta 1,4-GalT widely affects N-glycan processing by competing with GnT-IV, GnT-V, and alpha-mannosidase II in cells and also by some other mechanisms that suppress the conversion of high-mannose-type sugar chains to the hybrid type.	n-glycan	53-61	mannoside acetylglucosaminyltransferase 5	Mus musculus	99-104
11382750-4	2001	Here we report that N-glycan core alpha1,3-linked fucose is, as judged by preabsorption experiments, indispensable for recognition of Drosophila embryonic nervous system by anti-horseradish peroxidase antibody.	n-glycan	20-28	Peroxidase	Drosophila melanogaster	190-200
11483003-9	2001	Glycan analysis showed that both N-glycan and O-glycan chains were present in rC1INH.	n-glycan	33-41	serpin family G member 1	Rattus norvegicus	78-84
11382750-9	2001	The Drosophila core alpha1,3-fucosyltransferase enzyme was also shown to be able to fucosylate N-glycan structures of human transferrin in vitro, this modification correlating with the acquisition of binding to anti-horseradish peroxidase antibody.	n-glycan	95-103	alpha1,3-fucosyltransferase A	Drosophila melanogaster	15-47
11382750-9	2001	The Drosophila core alpha1,3-fucosyltransferase enzyme was also shown to be able to fucosylate N-glycan structures of human transferrin in vitro, this modification correlating with the acquisition of binding to anti-horseradish peroxidase antibody.	n-glycan	95-103	transferrin	Homo sapiens	124-135
11382750-9	2001	The Drosophila core alpha1,3-fucosyltransferase enzyme was also shown to be able to fucosylate N-glycan structures of human transferrin in vitro, this modification correlating with the acquisition of binding to anti-horseradish peroxidase antibody.	n-glycan	95-103	Peroxidase	Drosophila melanogaster	228-238
11454001-6	2001	An electrostatic interaction between this cationic amino acid and the core-sulfate group of the N-glycan is proposed to reduce mobility of the carbohydrate in the region of the t-PA active site.	n-glycan	96-104	plasminogen activator, tissue type	Homo sapiens	177-181
19003317-8	2001	The N-glycan patterns of recombinant human t-PA was also analysed with carbohydrate-specific lectins.	n-glycan	4-12	plasminogen activator, tissue type	Homo sapiens	43-47
11435503-2	2001	In the rat small intestine, O-glycan: beta-1,3-galactosyltransferase and N-glycan: beta-1,4-galactosyltransferase are, respectively, involved in the glycan chain biosynthesis of mucins and of glycoproteins in the brush border membranes.	n-glycan	73-81	glycoprotein alpha-galactosyltransferase 1	Rattus norvegicus	47-68
11447136-0	2001	N-glycan structure of a short-lived variant of ribophorin I expressed in the MadIA214 glycosylation-defective cell line reveals the role of a mannosidase that is not ER mannosidase I in the process of glycoprotein degradation.	n-glycan	0-8	ribophorin I	Homo sapiens	47-59
11447136-6	2001	An HA-epitope-tagged soluble variant of ribophorin I (RI(332)-3HA) expressed in MadIA214 cells was rapidly degraded, comparable to control cells with the complete Glc(3)Man(9)GlcNAc(2) N-glycan.	n-glycan	185-193	ribophorin I	Homo sapiens	40-52
11412044-2	2001	The role of conserved N-glycan sites in sorting, stability, and activity of tyrosinase family proteins was investigated using two family members from two different species, mouse gp75/tyrosinase-related protein (TRP)-1/Tyrp1 and human tyrosinase.	n-glycan	22-30	tyrosinase	Homo sapiens	76-86
11412044-4	2001	Our results show that selected conserved N-glycan sites on tyrosinase family members are crucial for stability in the secretory pathway and endocytic compartment and for enzymatic activity.	n-glycan	41-49	tyrosinase	Homo sapiens	59-69
11435503-2	2001	In the rat small intestine, O-glycan: beta-1,3-galactosyltransferase and N-glycan: beta-1,4-galactosyltransferase are, respectively, involved in the glycan chain biosynthesis of mucins and of glycoproteins in the brush border membranes.	n-glycan	73-81	glycoprotein alpha-galactosyltransferase 1	Rattus norvegicus	92-113
11257601-4	2001	Although both CHO and NS0-derived oligosaccharides were predominantly of the standard complex type with variable sialylation, 30% of N-glycan antennae associated with NS0-derived TIMP-1 terminated in alpha1,3-linked galactose residues.	n-glycan	133-141	tissue inhibitor of metalloproteinase 1	Mus musculus	179-185
11406577-1	2001	Golgi alpha-mannosidase II, a key enzyme in N-glycan processing, is a target in the development of anti- cancer therapies.	n-glycan	44-52	alpha-Mannosidase class II a	Drosophila melanogaster	0-26
11375934-5	2001	Although the luminal region of ER degradation enhancing alpha-mannosidase-like protein (EDEM) is similar to class I alpha1,2-mannosidases involved in N-glycan processing, EDEM did not have enzymatic activity.	n-glycan	150-158	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	31-86
11375934-5	2001	Although the luminal region of ER degradation enhancing alpha-mannosidase-like protein (EDEM) is similar to class I alpha1,2-mannosidases involved in N-glycan processing, EDEM did not have enzymatic activity.	n-glycan	150-158	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	88-92
11375934-7	2001	The results suggest that EDEM is directly involved in ERAD, and targets misfolded glycoproteins for degradation in an N-glycan dependent manner.	n-glycan	118-126	ER degradation enhancing alpha-mannosidase like protein 1	Homo sapiens	25-29
11315257-10	2001	CONCLUSIONS: The alteration of N-glycan structure in surface glycoproteins resulting from the activity change of GnT-V contributes to the alterations in metastasis-associated phenotypes.	n-glycan	31-39	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	113-118
11024053-9	2001	Thus, the addition of a specific N-glycan structure, the bisecting GlcNAc to E-cadherin-beta-catenin complex, down-regulates the intracellular signaling pathway, suggesting its implication in cell motility and the suppression of cancer metastasis.	n-glycan	33-41	cadherin 1	Mus musculus	77-87
11222938-2	2001	We previously cloned and characterized an insect alpha 1,2-mannosidase cDNA and demonstrated that it encodes a member of a family of N-glycan processing alpha 1,2-mannosidases (Kawar, Z., Herscovics, A., Jarvis, D.L., 1997.	n-glycan	133-141	mannosidase alpha class 1A member 2	Homo sapiens	49-70
11231279-0	2001	Overexpression of the Golgi-localized enzyme alpha-mannosidase IIx in Chinese hamster ovary cells results in the conversion of hexamannosyl-N-acetylchitobiose to tetramannosyl-N-acetylchitobiose in the N-glycan-processing pathway.	n-glycan	202-210	alpha-mannosidase 2x	Cricetulus griseus	45-66
11231279-8	2001	The results suggest that alpha-mannosidase IIx hydrolyzes two peripheral Man alpha 1-->6 and Man alpha 1-->3 residues from [(Man alpha 1-->6)(Man alpha 1-->3)Man alpha 1-->6](Man alpha 1-->2Man alpha 1-->3)Man beta 1-->4GlcNAc beta 1-->4GlcNAc, during N-glycan processing.	n-glycan	279-287	mannosidase alpha class 2A member 2	Homo sapiens	25-46
11076950-6	2001	This staining was diminished after digestion of the glycans with endo-beta-N-acetylglucosaminidase H or D, suggesting that at least a N-glycan containing Man(5)GlcNAc(2) is linked to the extracellular portion of the IL-2 receptor alpha subunit.	n-glycan	134-142	interleukin 2 receptor subunit alpha	Homo sapiens	216-235
11024053-9	2001	Thus, the addition of a specific N-glycan structure, the bisecting GlcNAc to E-cadherin-beta-catenin complex, down-regulates the intracellular signaling pathway, suggesting its implication in cell motility and the suppression of cancer metastasis.	n-glycan	33-41	catenin (cadherin associated protein), beta 1	Mus musculus	88-100
11185549-2	2000	To help understand the mechanics and kinetics of dissociation of receptor-ligand complexes, we have analyzed the separation of lactose and the N-glycan chains of asialofetuin (ASF) from three lectins and an immunoglobulin G fraction by surface plasmon resonance at zero force and by atomic force microscopy with variations of the external force.	n-glycan	143-151	alpha 2-HS glycoprotein	Bos taurus	162-174
11511812-0	2000	The N-glycan acceptor specificity of a glucuronyltransferase, GlcAT-P, associated with biosynthesis of the HNK-1 epitope.	n-glycan	4-12	beta-1,3-glucuronyltransferase 1	Rattus norvegicus	62-69
11511812-0	2000	The N-glycan acceptor specificity of a glucuronyltransferase, GlcAT-P, associated with biosynthesis of the HNK-1 epitope.	n-glycan	4-12	beta-1,3-glucuronyltransferase 1	Rattus norvegicus	107-112
10915796-0	2000	Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.	n-glycan	96-104	mannosidase alpha class 1A member 2	Homo sapiens	56-78
10942758-9	2000	We conclude that at least one N-glycan per subunit of either position is absolutely required for the formation of P2X(1) receptors and that individual N-glycans possess marked positional effects on expression levels (Asn(154), Asn(210)) and ATP potency (Asn(210)).	n-glycan	30-38	purinergic receptor P2X 1	Rattus norvegicus	114-120
11023510-0	2000	A hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity.	n-glycan	81-89	selectin L	Homo sapiens	21-31
10915799-0	2000	Folding and maturation of tyrosinase-related protein-1 are regulated by the post-translational formation of disulfide bonds and by N-glycan processing.	n-glycan	131-139	tyrosinase-related protein 1	Mus musculus	26-54
10929010-0	2000	N-glycan patterns of human transferrin produced in Trichoplusia ni insect cells: effects of mammalian galactosyltransferase.	n-glycan	0-8	transferrin	Homo sapiens	27-38
10852913-9	2000	In vitro translation and ex vivo expression showed that RhCG carries a complex N-glycan, probably at the (48)NLS(50) sequon of exoloop 1.	n-glycan	79-87	Rh family C glycoprotein	Homo sapiens	56-60
11030742-7	2000	Due to three negatively charged SiaLe(x) groups per N-glycan, the surface electrostatic properties change to a negative electrostatic field covering most of the C-terminal part, including the surface of Helix-B and Helix-C, while the positively charged N-terminal part PrP(90-126) of undefined structure creates a positive potential.	n-glycan	52-60	prion protein	Homo sapiens	269-272
10987826-8	2000	These results suggest that the N-glycan of PMP22 facilitates, in part, the stability of the PMP22 oligomer; however, the implications of PMP22 oligomerization remain unknown.	n-glycan	31-39	peripheral myelin protein 22	Homo sapiens	43-48
10987826-8	2000	These results suggest that the N-glycan of PMP22 facilitates, in part, the stability of the PMP22 oligomer; however, the implications of PMP22 oligomerization remain unknown.	n-glycan	31-39	peripheral myelin protein 22	Homo sapiens	92-97
10987826-8	2000	These results suggest that the N-glycan of PMP22 facilitates, in part, the stability of the PMP22 oligomer; however, the implications of PMP22 oligomerization remain unknown.	n-glycan	31-39	peripheral myelin protein 22	Homo sapiens	92-97
10929010-3	2000	Consequently, the N-glycan structures of transferrin in the culture medium were determined using three-dimensional high performance liquid chromatography.	n-glycan	18-26	transferrin	Homo sapiens	41-52
10749681-1	2000	Oncogenic transformation of fibroblasts by the src oncogene has long been known to cause an increase in the size of cell-surface protein-bound oligosaccharides, owing primarily to increased N-glycan branching mediated by increased beta-1,6-N-acetylglucosaminyltransferase V (GnT V) activity.	n-glycan	190-198	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	47-50
10818229-1	2000	Corticosteroid binding globulin, a member of the serpin family, was previously shown to be secreted mainly apically from MDCK cells in an N-glycan independent manner [Larsen et al.	n-glycan	138-146	serpin family A member 6	Canis lupus familiaris	0-31
10644004-5	1999	In this report we investigate the effects of the perturbation of N-glycan processing in ER on the transport and activation of tyrosinase and TRP-1.	n-glycan	65-73	tyrosinase	Mus musculus	126-136
10753911-0	2000	Mutation of Arg(273) to Leu alters the specificity of the yeast N-glycan processing class I alpha1,2-mannosidase.	n-glycan	64-72	mannosidase alpha class 1A member 2	Homo sapiens	92-112
10764822-0	2000	N-Glycan processing by a lepidopteran insect alpha1,2-mannosidase.	n-glycan	0-8	mannosidase alpha class 1A member 2	Homo sapiens	45-65
10675327-0	2000	Crystal structure of a class I alpha1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control.	n-glycan	64-72	mannosidase alpha class 1A member 2	Homo sapiens	31-51
10675327-2	2000	The crystal structure of the class I alpha1, 2-mannosidase that trims Man(9)GlcNAc(2) to Man(8)GlcNAc(2 )isomer B in the endoplasmic reticulum of Saccharomyces cerevisiae reveals a novel (alphaalpha)(7)-barrel in which an N-glycan from one molecule extends into the barrel of an adjacent molecule, interacting with the essential acidic residues and calcium ion.	n-glycan	222-230	mannosidase alpha class 1A member 2	Homo sapiens	37-58
10646865-11	2000	These results suggest that the increased beta1,6-GlcNAc-bearing N-glycan expression found in malignant gliomas is modulated by GnT-V through the Ets-1 transcription factor, and that the branching of complex type N-glycans plays a major role in glioma invasivity.	n-glycan	64-72	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	41-46
10646865-11	2000	These results suggest that the increased beta1,6-GlcNAc-bearing N-glycan expression found in malignant gliomas is modulated by GnT-V through the Ets-1 transcription factor, and that the branching of complex type N-glycans plays a major role in glioma invasivity.	n-glycan	64-72	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	127-132
10646865-11	2000	These results suggest that the increased beta1,6-GlcNAc-bearing N-glycan expression found in malignant gliomas is modulated by GnT-V through the Ets-1 transcription factor, and that the branching of complex type N-glycans plays a major role in glioma invasivity.	n-glycan	64-72	ETS proto-oncogene 1, transcription factor	Homo sapiens	145-150
10691987-14	2000	Analysis of the oligosaccharide moiety of the RNase 1 secreted by Capan-1 shows that it is highly glycosylated and its N-glycan chains are significantly different from that of the RNase 1 produced by normal pancreas.	n-glycan	119-127	ribonuclease A family member 1, pancreatic	Homo sapiens	46-53
10679288-0	2000	N-Glycan structures of an osteopontin from human bone.	n-glycan	0-8	secreted phosphoprotein 1	Homo sapiens	26-37
10679288-1	2000	N-Glycan structures of osteopontin (a bone matrix protein) from human bone (lumbar vertabrate) are reported in detail.	n-glycan	0-8	secreted phosphoprotein 1	Homo sapiens	23-34
10782293-4	2000	MS analysis of the esterified N-glycan pool derived from DAO indicated the presence of several di- and trisialylated structures.	n-glycan	30-38	amine oxidase copper containing 1	Homo sapiens	57-60
11250723-2	2000	Associations linking the importance of glycosylation events to tumor biology, especially the progression to metastatic disease, have been noted over many years, Recently, a mouse model in which beta1,6-N-acetylglucosaminyltransferase V (a rate-limiting enzyme in the N-glycan pathway) has been knocked out, was used to demonstrate the importance of glycosylation in tumor progression.	n-glycan	267-275	mannoside acetylglucosaminyltransferase 5	Mus musculus	194-235
10585852-4	1999	We have recently shown that inhibition of the early steps of N-glycan processing in B16F1 cells dramatically affects tyrosinase activity and melanin synthesis.	n-glycan	61-69	tyrosinase	Mus musculus	117-127
10585852-5	1999	We present here results on N-glycan processing of TRP-1 and tyrosinase and compare the maturation process and activity of both glycoproteins in the presence of inhibitors of the endoplasmic reticulum stages of N-glycosylation.	n-glycan	27-35	tyrosinase-related protein 1	Mus musculus	50-55
10585852-5	1999	We present here results on N-glycan processing of TRP-1 and tyrosinase and compare the maturation process and activity of both glycoproteins in the presence of inhibitors of the endoplasmic reticulum stages of N-glycosylation.	n-glycan	27-35	tyrosinase	Mus musculus	60-70
10585852-10	1999	The results suggest that despite their structural similarity, tyrosinase is more sensitive than TRP-1 to perturbations of early N-glycan processing, in terms of maturation and catalytical activity.	n-glycan	128-136	tyrosinase	Mus musculus	62-72
10585852-10	1999	The results suggest that despite their structural similarity, tyrosinase is more sensitive than TRP-1 to perturbations of early N-glycan processing, in terms of maturation and catalytical activity.	n-glycan	128-136	tyrosinase-related protein 1	Mus musculus	96-101
10644004-5	1999	In this report we investigate the effects of the perturbation of N-glycan processing in ER on the transport and activation of tyrosinase and TRP-1.	n-glycan	65-73	tyrosinase-related protein 1	Mus musculus	141-146
10521544-0	1999	Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis.	n-glycan	119-127	mannosidase alpha class 1A member 2	Homo sapiens	43-64
10521544-5	1999	The properties and specificity of this human alpha 1,2-mannosidase are identical to the endoplasmic reticulum alpha 1,2-mannosidase from Saccharomyces cerevisiae and differ from those of previously cloned Golgi alpha 1,2-mannosidases that remove up to four mannose residues from Man9GlcNAc2 during N-glycan maturation.	n-glycan	298-306	mannosidase alpha class 1A member 2	Homo sapiens	45-66
10521544-5	1999	The properties and specificity of this human alpha 1,2-mannosidase are identical to the endoplasmic reticulum alpha 1,2-mannosidase from Saccharomyces cerevisiae and differ from those of previously cloned Golgi alpha 1,2-mannosidases that remove up to four mannose residues from Man9GlcNAc2 during N-glycan maturation.	n-glycan	298-306	mannosidase alpha class 1A member 2	Homo sapiens	110-131
10462499-3	1999	These data show that calnexin interaction with class I proteins having truncated N-glycans was reduced compared to normal class I molecules, whereas the assembly of class I with calreticulin and TAP was unperturbed by N-glycan chain length.	n-glycan	81-89	calnexin	Homo sapiens	21-29
10471642-6	1999	RESULTS: In patients with alcoholism, the abnormal transferrin and alpha(1)-antitrypsin isoforms were devoid of a variable number of entire N-glycan moieties and were identical with those present in CDG1.	n-glycan	140-148	transferrin	Homo sapiens	51-62
10471642-6	1999	RESULTS: In patients with alcoholism, the abnormal transferrin and alpha(1)-antitrypsin isoforms were devoid of a variable number of entire N-glycan moieties and were identical with those present in CDG1.	n-glycan	140-148	serpin family A member 1	Homo sapiens	67-87
10485384-3	1999	In this study, we investigated the involvement of N-glycan on phospholipase A2 (PLA2), the major allergen of honeybee venom, in in vivo synthesis of specific IgE in mice.	n-glycan	50-58	phospholipase A2	Apis mellifera	62-78
10441371-5	1999	Finally, these results show that CD69 proteins lacking atypical or typical N-glycan addition sites are transported to the plasma membrane.	n-glycan	75-83	CD69 molecule	Homo sapiens	33-37
10485384-3	1999	In this study, we investigated the involvement of N-glycan on phospholipase A2 (PLA2), the major allergen of honeybee venom, in in vivo synthesis of specific IgE in mice.	n-glycan	50-58	phospholipase A2	Apis mellifera	80-84
10417322-10	1999	Treatment with tunicamycin (TUN) diminished the binding of MUC2 to CRT, suggesting a requirement for initial N-glycan addition during this process.	n-glycan	109-117	mucin 2, oligomeric mucus/gel-forming	Homo sapiens	59-63
10417322-10	1999	Treatment with tunicamycin (TUN) diminished the binding of MUC2 to CRT, suggesting a requirement for initial N-glycan addition during this process.	n-glycan	109-117	calreticulin	Homo sapiens	67-70
10737326-0	1999	N-glycan structures of murine hippocampus serine protease, neuropsin, produced in Trichoplusia ni cells.	n-glycan	0-8	opsin 5	Mus musculus	59-68
10737326-0	1999	N-glycan structures of murine hippocampus serine protease, neuropsin, produced in Trichoplusia ni cells.	n-glycan	0-8	complement component 1, s subcomponent 1	Mus musculus	42-57
10737326-4	1999	The presence of insect specific N-glycan structures containing both alpha1,3- and alpha1,6- di-fucosylated innermost N-acetylglucosamine residue (23.3%), as below, was also confirmed by 600 MHz 1H-NMR spectroscopy.	n-glycan	32-40	cholinergic receptor, nicotinic, alpha polypeptide 3	Mus musculus	68-91
10364366-4	1999	Complete processing of the complex-type sugar appears to be required for efficient release of soluble NS1 into the culture fluid of infected cells, as suggested by the repressive effects of the N-glycan processing inhibitors swainsonine and deoxymannojyrimicin.	n-glycan	194-202	influenza virus NS1A binding protein	Homo sapiens	102-105
10223333-8	1999	Calnexin selectively binds to the N-glycan, specific for M, rather than to the N-glycan, common to all three envelope proteins.	n-glycan	34-42	calnexin	Homo sapiens	0-8
10405183-6	1999	Introduction of a single N-glycan caused 83% of the growth hormone to be secreted at the apical surface in MDCK cells but had no significant effect on the polarity of secretion of growth hormone in ECV304 cells.	n-glycan	25-33	somatotropin	Canis lupus familiaris	52-66
10364189-10	1999	These associations were inhibited in vivo by deoxynojirimycin, an inhibitor of N-glycan precusor trimming that is known to prevent the calnexin/calreticulin-N-glycan interaction.	n-glycan	79-87	calnexin	Homo sapiens	135-143
10364189-10	1999	These associations were inhibited in vivo by deoxynojirimycin, an inhibitor of N-glycan precusor trimming that is known to prevent the calnexin/calreticulin-N-glycan interaction.	n-glycan	79-87	calreticulin	Homo sapiens	144-156
10364189-10	1999	These associations were inhibited in vivo by deoxynojirimycin, an inhibitor of N-glycan precusor trimming that is known to prevent the calnexin/calreticulin-N-glycan interaction.	n-glycan	157-165	calnexin	Homo sapiens	135-143
10364189-10	1999	These associations were inhibited in vivo by deoxynojirimycin, an inhibitor of N-glycan precusor trimming that is known to prevent the calnexin/calreticulin-N-glycan interaction.	n-glycan	157-165	calreticulin	Homo sapiens	144-156
10364189-11	1999	Functional expression of the unglycosylated SERT mutant, SERT-QQ, was also increased on co-expression of calnexin, suggesting that the interaction between calnexin and SERT is not entirely dictated by the N-glycan.	n-glycan	205-213	solute carrier family 6 member 4	Homo sapiens	44-48
10364189-11	1999	Functional expression of the unglycosylated SERT mutant, SERT-QQ, was also increased on co-expression of calnexin, suggesting that the interaction between calnexin and SERT is not entirely dictated by the N-glycan.	n-glycan	205-213	solute carrier family 6 member 4	Homo sapiens	57-61
10364189-11	1999	Functional expression of the unglycosylated SERT mutant, SERT-QQ, was also increased on co-expression of calnexin, suggesting that the interaction between calnexin and SERT is not entirely dictated by the N-glycan.	n-glycan	205-213	solute carrier family 6 member 4	Homo sapiens	57-61
10406121-10	1999	All four XETs are glycosylated; however, only the activities of TCH4 and Meri-5 are affected by the removal of the N-glycan with PNGase F. These four enzymes most likely function solely as transglycosylases because xyloglucan endoglucanase activity was not apparent.	n-glycan	115-123	Xyloglucan endotransglucosylase/hydrolase family protein	Arabidopsis thaliana	64-68
10082988-3	1999	This enzymatic deglycosylation product was enough to explore possibilities that N-glycan might modify some properties of human chymase.	n-glycan	80-88	chymase 1	Homo sapiens	127-134
10082988-10	1999	From these results, it appears that the N-glycan of human chymase contributes to the stability of this enzyme but not to its functional properties.	n-glycan	40-48	chymase 1	Homo sapiens	58-65
10223333-8	1999	Calnexin selectively binds to the N-glycan, specific for M, rather than to the N-glycan, common to all three envelope proteins.	n-glycan	79-87	calnexin	Homo sapiens	0-8
9600268-0	1998	Importance of the N-glycan in the V3 loop of HIV-1 envelope protein for CXCR-4- but not CCR-5-dependent fusion.	n-glycan	18-26	C-X-C motif chemokine receptor 4	Homo sapiens	72-78
10092871-0	1999	N-glycan structures of matrix metalloproteinase-1 derived from human fibroblasts and from HT-1080 fibrosarcoma cells.	n-glycan	0-8	matrix metallopeptidase 1	Homo sapiens	23-49
10092871-6	1999	Using strategies based on sequential exoglycosidase digestion combined with matrix-assisted laser desorption ionization-time of flight MS and electrospray tandem MS, we have characterized the N-glycan structures of MMP-1, derived from human dermal fibroblasts and from the HT-1080 fibrosarcoma cell line.	n-glycan	192-200	matrix metallopeptidase 1	Homo sapiens	215-220
9763440-1	1998	CWH41, a gene involved in the assembly of cell wall beta-1,6-glucan, has recently been shown to be the structural gene for Saccharomyces cerevisiae glucosidase I that is responsible for initiating the trimming of terminal alpha-1,2-glucose residue in the N-glycan processing pathway.	n-glycan	255-263	mannosyl-oligosaccharide glucosidase	Saccharomyces cerevisiae S288C	0-5
9592125-0	1998	Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha1,2-mannosidase gene involved in N-glycan maturation.	n-glycan	125-133	mannosidase alpha class 1A member 2	Homo sapiens	87-107
9989600-7	1999	Determination of the N-glycan structures (dHex, Hex and HexNAc) was assessed by nanoESMS/MS with picomolar amounts of sample.	n-glycan	21-29	Hex1	Drosophila melanogaster	42-46
9989600-7	1999	Determination of the N-glycan structures (dHex, Hex and HexNAc) was assessed by nanoESMS/MS with picomolar amounts of sample.	n-glycan	21-29	Hex1	Drosophila melanogaster	43-46
9774483-6	1998	These results indicate that both PST and STX have relatively broad specificity on N-glycan core structures in NCAM and no remarkable difference exists between PST and STX for the requirement of core structures and sialic acid attached to the N-glycans of NCAM.	n-glycan	82-90	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	Homo sapiens	33-36
9774483-6	1998	These results indicate that both PST and STX have relatively broad specificity on N-glycan core structures in NCAM and no remarkable difference exists between PST and STX for the requirement of core structures and sialic acid attached to the N-glycans of NCAM.	n-glycan	82-90	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	Homo sapiens	41-44
9774483-6	1998	These results indicate that both PST and STX have relatively broad specificity on N-glycan core structures in NCAM and no remarkable difference exists between PST and STX for the requirement of core structures and sialic acid attached to the N-glycans of NCAM.	n-glycan	82-90	neural cell adhesion molecule 1	Homo sapiens	110-114
10211705-2	1998	Two glycopeptides, GP1 and GP2, prepared from the endoproteinase Asp-N digest of the IgA1 heavy chain, were derived from the CH2 domain (N-glycan site at Asn263) and the tailpiece portion (N-glycan site at Asn459), respectively.	n-glycan	137-145	GTP binding protein 1	Homo sapiens	19-22
10211705-2	1998	Two glycopeptides, GP1 and GP2, prepared from the endoproteinase Asp-N digest of the IgA1 heavy chain, were derived from the CH2 domain (N-glycan site at Asn263) and the tailpiece portion (N-glycan site at Asn459), respectively.	n-glycan	137-145	glycoprotein 2	Homo sapiens	27-30
10211705-2	1998	Two glycopeptides, GP1 and GP2, prepared from the endoproteinase Asp-N digest of the IgA1 heavy chain, were derived from the CH2 domain (N-glycan site at Asn263) and the tailpiece portion (N-glycan site at Asn459), respectively.	n-glycan	189-197	GTP binding protein 1	Homo sapiens	19-22
10211705-2	1998	Two glycopeptides, GP1 and GP2, prepared from the endoproteinase Asp-N digest of the IgA1 heavy chain, were derived from the CH2 domain (N-glycan site at Asn263) and the tailpiece portion (N-glycan site at Asn459), respectively.	n-glycan	189-197	glycoprotein 2	Homo sapiens	27-30
10211705-2	1998	Two glycopeptides, GP1 and GP2, prepared from the endoproteinase Asp-N digest of the IgA1 heavy chain, were derived from the CH2 domain (N-glycan site at Asn263) and the tailpiece portion (N-glycan site at Asn459), respectively.	n-glycan	189-197	immunoglobulin heavy constant alpha 1	Homo sapiens	85-89
9600268-5	1998	These results indicate that the N-glycan plays an important role for CXCR-4-dependent virus entry and that this role is exerted in a particular context of the peptide backbone.	n-glycan	32-40	C-X-C motif chemokine receptor 4	Homo sapiens	69-75
9579808-0	1998	Transcriptional regulation of the human UDP-GlcNAc:alpha-6-D-mannoside beta-1-2-N-acetylglucosaminyltransferase II gene (MGAT2) which controls complex N-glycan synthesis.	n-glycan	151-159	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	121-126
9545549-4	1998	Further analysis of the isolated transferrin forms by matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MS) and enzyme linked immunosorbent assay with different digoxigenylated lectins (lectin ELISA) revealed that the main carbohydrate deficient transferrin (CDT) forms are lacking either one or both of the N-Glycan chains.	n-glycan	346-354	transferrin	Homo sapiens	33-44
9551918-3	1998	We asked whether addition of a second N-glycan to the human class I molecule A*0201 at position 176, a site present in mouse, would affect its binding to calnexin.	n-glycan	38-46	calnexin	Mus musculus	154-162
9551918-4	1998	The 176dg mutant with N-glycans at positions 86 and 176, when transfected into CIR cells, demonstrated increased binding to calnexin, detectable both before and after association with beta2m, and reduced interaction with calreticulin and TAP relative to wild-type protein bearing a single N-glycan at position 86.	n-glycan	22-30	calnexin	Homo sapiens	124-132
9551918-4	1998	The 176dg mutant with N-glycans at positions 86 and 176, when transfected into CIR cells, demonstrated increased binding to calnexin, detectable both before and after association with beta2m, and reduced interaction with calreticulin and TAP relative to wild-type protein bearing a single N-glycan at position 86.	n-glycan	22-30	beta-2-microglobulin	Homo sapiens	184-190
9261166-7	1997	We suggest that the PrP molecule has an intrinsic tendency to acquire some PrPSc-like properties, and that N-glycan chains protect against this change.	n-glycan	107-115	prion protein	Mus musculus	20-23
9486427-11	1997	Therefore, the removal of sialic acid moieties from the single N-glycan of each monomer apparently affects surface presentation of distinct CIDNP-reactive amino acids of SAP [1].	n-glycan	63-71	amyloid P component, serum	Homo sapiens	170-173
9524927-13	1997	Firmly bound apolipoprotein H referred to molecules rich in N-glycan hybrid structures.	n-glycan	60-68	apolipoprotein H	Homo sapiens	13-29
9395316-8	1997	N-glycan processing in T. reesei apparently involves different steps, including alpha-1,2-mannosidase trimmings, and thus resembles the first mammalian glycosylation processes.	n-glycan	0-8	mannosidase alpha class 1A member 2	Homo sapiens	80-101
9312167-4	1997	The affected individuals with the Arg589 mutations had reduced red cell sulfate transport and altered glycosylation of the red cell band 3 N-glycan chain.	n-glycan	139-147	solute carrier family 4 member 1 (Diego blood group) L homeolog	Xenopus laevis	132-138
9244386-10	1997	High-pH anion-exchange chromatography analysis indicated that the recombinant forms of BSSL contained similar types of N-glycan structures differing mainly in their content of sialic acid and by the absence of fucose residues.	n-glycan	119-127	carboxyl ester lipase	Homo sapiens	87-91
9219849-7	1997	Furthermore, the modification of N-glycan on CEA by deoxymannojirimycin, an N-glycosylation processing inhibitor, partially restored ADR sensitivity of CEA transfectants, suggesting an involvement of sugar chains.	n-glycan	33-41	carcinoembryonic antigen gene family	Mus musculus	45-48
9219849-7	1997	Furthermore, the modification of N-glycan on CEA by deoxymannojirimycin, an N-glycosylation processing inhibitor, partially restored ADR sensitivity of CEA transfectants, suggesting an involvement of sugar chains.	n-glycan	33-41	carcinoembryonic antigen gene family	Mus musculus	152-155
9061364-4	1997	GlcNAc-TIII can also play a regulatory role in N-glycan biosynthesis as addition of the bisecting GlcNAc eliminates the potential for alpha-mannosidase-II, GlcNAc-TII, GlcNAc-TIV, GlcNAc-TV, and core alpha 1-6-fucosyltransferase to act subsequently.	n-glycan	47-55	mannoside acetylglucosaminyltransferase 3	Mus musculus	0-11
9188477-0	1997	Inhibition of N-glycan processing in B16 melanoma cells results in inactivation of tyrosinase but does not prevent its transport to the melanosome.	n-glycan	14-22	tyrosinase	Mus musculus	83-93
9188477-3	1997	In this study, we have investigated the effects of inhibitors of N-glycan processing on the synthesis, transport, and catalytic activity of tyrosinase.	n-glycan	65-73	tyrosinase	Mus musculus	140-150
9092490-8	1997	These results indicate that overexpression of GnT-III gene in PC12 cells affects some functions of glycoprotein receptors such as Trk by alteration of N-glycan structures, and results in changes in the intracellular signaling pathway of tyrosine phosphorylation modified by NGF.	n-glycan	151-159	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Rattus norvegicus	46-53
9092490-8	1997	These results indicate that overexpression of GnT-III gene in PC12 cells affects some functions of glycoprotein receptors such as Trk by alteration of N-glycan structures, and results in changes in the intracellular signaling pathway of tyrosine phosphorylation modified by NGF.	n-glycan	151-159	neurotrophic receptor tyrosine kinase 1	Rattus norvegicus	130-133
9153243-4	1997	As with soluble proteins, the binding of ERp57 to an integral membrane protein is dependent upon the protein bearing an N-glycan that has undergone glucose trimming.	n-glycan	120-128	protein disulfide isomerase family A member 3	Homo sapiens	41-46
9143489-0	1997	Genomic organization and chromosomal mapping of the murine alpha 1,2-mannosidase IB involved in N-glycan maturation.	n-glycan	96-104	mannosidase, alpha, class 1A, member 2	Mus musculus	59-83
9061364-4	1997	GlcNAc-TIII can also play a regulatory role in N-glycan biosynthesis as addition of the bisecting GlcNAc eliminates the potential for alpha-mannosidase-II, GlcNAc-TII, GlcNAc-TIV, GlcNAc-TV, and core alpha 1-6-fucosyltransferase to act subsequently.	n-glycan	47-55	mannoside acetylglucosaminyltransferase 2	Mus musculus	0-10
9061364-4	1997	GlcNAc-TIII can also play a regulatory role in N-glycan biosynthesis as addition of the bisecting GlcNAc eliminates the potential for alpha-mannosidase-II, GlcNAc-TII, GlcNAc-TIV, GlcNAc-TV, and core alpha 1-6-fucosyltransferase to act subsequently.	n-glycan	47-55	mannoside acetylglucosaminyltransferase 5	Mus musculus	180-189
8942648-14	1996	Furthermore, we propose that the C-terminal domain of TPO be further divided into two domains on the basis of sequence homology among the cloned sequences and glycosylation/structural features: an N-glycan domain (154-246) and an O-glycan domain (247-332).	n-glycan	197-205	thrombopoietin	Homo sapiens	54-57
9020882-0	1997	Organization of the human beta-1,2-N-acetylglucosaminyltransferase I gene (MGAT1), which controls complex and hybrid N-glycan synthesis.	n-glycan	117-125	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	75-80
9022667-1	1996	Golgi alpha-mannosidase II is a key enzyme of N-glycan processing.	n-glycan	46-54	mannosidase alpha class 2A member 1	Homo sapiens	0-26
9020857-11	1997	These results indicate that Kre2p/ Mnt1p and Ktr1p are capable of participating in both N-glycan and O-glycan biosynthesis.	n-glycan	88-96	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	28-33
9020857-11	1997	These results indicate that Kre2p/ Mnt1p and Ktr1p are capable of participating in both N-glycan and O-glycan biosynthesis.	n-glycan	88-96	alpha-1,2-mannosyltransferase KRE2	Saccharomyces cerevisiae S288C	35-40
9020857-11	1997	These results indicate that Kre2p/ Mnt1p and Ktr1p are capable of participating in both N-glycan and O-glycan biosynthesis.	n-glycan	88-96	alpha-1,2-mannosyltransferase KTR1	Saccharomyces cerevisiae S288C	45-50
8977219-4	1997	Moreover, the relative susceptibility to these enzymes and accessibility to lectins was inversely related to the capacity of the Abs to activate the classical pathway, suggesting that the orientation of the more accessible N-glycan might inhibit C1q binding.	n-glycan	223-231	complement C1q A chain	Homo sapiens	246-249
8977219-5	1997	This hypothesis was supported by evidence that enzymatic cleavage of the more accessible N-glycan resulted in enhanced Clq, C4b, and C3b deposition.	n-glycan	89-97	complement C4B (Chido blood group)	Homo sapiens	124-127
8977219-5	1997	This hypothesis was supported by evidence that enzymatic cleavage of the more accessible N-glycan resulted in enhanced Clq, C4b, and C3b deposition.	n-glycan	89-97	endogenous retrovirus group K member 3	Homo sapiens	133-136
8977219-6	1997	Conversely, removal of the less accessible N-glycan expressed by the other Ab inhibited C1q, C4b, and C3b deposition.	n-glycan	43-51	complement C1q A chain	Homo sapiens	88-91
8977219-6	1997	Conversely, removal of the less accessible N-glycan expressed by the other Ab inhibited C1q, C4b, and C3b deposition.	n-glycan	43-51	complement C4B (Chido blood group)	Homo sapiens	93-96
8977219-6	1997	Conversely, removal of the less accessible N-glycan expressed by the other Ab inhibited C1q, C4b, and C3b deposition.	n-glycan	43-51	endogenous retrovirus group K member 3	Homo sapiens	102-105
8977219-7	1997	The respective increase or decrease in C3b deposition on the two deglycosylated Abs was magnified when complement activation was performed in factor B-depleted serum, suggesting that N-glycan conformation primarily affects the classical pathway.	n-glycan	183-191	endogenous retrovirus group K member 3	Homo sapiens	39-42
8808595-0	1996	Mutations in the MGAT2 gene controlling complex N-glycan synthesis cause carbohydrate-deficient glycoprotein syndrome type II, an autosomal recessive disease with defective brain development.	n-glycan	48-56	alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	17-22
7664874-11	1995	Therefore, the removal of sialic acid moieties from the single N-glycan of each monomer apparently affects surface presentation of distinct CIDNP-reactive amino acids of SAP.	n-glycan	63-71	amyloid P component, serum	Homo sapiens	170-173
8764003-8	1996	These results indicate that the N-glycan attached to SCR2 is essential for MCP to serve as a measles virus receptor, while the oligosaccharides attached to SCR1 and SCR4 are of only minor importance.	n-glycan	32-40	RNA binding motif single stranded interacting protein 1	Homo sapiens	53-57
8615015-1	1996	A conserved N-glycan present within the V3 loop of gp120 modulates the sensitivity to neutralization by antibodies directed to the V3 loop.	n-glycan	12-20	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	51-56
10608038-0	1996	Comparison of N-Glycan Pattern of Recombinant Human Coagulation Factors II and IX Expressed in Chinese Hamster Ovary (CHO) and African Green Monkey (Vero) Cells.	n-glycan	14-22	coagulation factor II, thrombin	Homo sapiens	52-81
7501023-6	1995	Galectin-1-induced apoptosis required expression of CD45, and was decreased when N-glycan elongation was blocked by treatment of the cells by swainsonine, whereas inhibition of O-glycan elongation potentiated the apoptotic effect of galectin-1.	n-glycan	81-89	galectin 1	Homo sapiens	0-10
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	35-43	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	62-70
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	35-43	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	62-68
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	35-43	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	75-81
9634799-5	1995	Transgenic mouse derived IFN-gamma exhibited considerable site-specific variation in N-glycan structures.	n-glycan	85-93	interferon gamma	Mus musculus	25-34
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	35-43	adrenoceptor alpha 1D	Homo sapiens	48-55
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	230-238	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	62-70
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	230-238	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	62-68
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	230-238	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	Homo sapiens	75-81
7794934-1	1995	The conformational behavior of the N-glycan Man alpha 1-6(Xyl beta 1-2)Man beta 1-4GlcNAc beta 1-4(Fuc alpha 1-3)GlcNAc beta of stem bromelain as part of the intact glycoprotein was investigated and compared with that of the same N-glycan as part of a bromelain-derived glycopeptide.	n-glycan	230-238	adrenoceptor alpha 1D	Homo sapiens	48-55
7852349-5	1995	Reconstituted type I collagen fibrils were able to bind in vitro native and N-glycan-free biglycan as well as recombinant biglycan core protein.	n-glycan	76-84	biglycan	Homo sapiens	90-98
7781780-0	1995	Identification and structural characterization of a mannose-6-phosphate containing oligomannosidic N-glycan from human erythropoietin secreted by recombinant BHK-21 cells.	n-glycan	99-107	erythropoietin	Homo sapiens	119-133
7781780-1	1995	A sialidase resistant mono-charged N-glycan was isolated from glycosylation site I (Asn-24) of recombinant human erythropoietin expressed from baby hamster kidney (BHK-21) cells and constituted approximately 2-4% of the oligosaccharide material at this glycosylation site.	n-glycan	35-43	erythropoietin	Homo sapiens	113-127
8043873-6	1994	In contrast, the size of the N-glycan chain on the glucose transporter (GLUT1) from MkMk cells was smaller than that on GLUT1 from normal cells.	n-glycan	29-37	solute carrier family 2 member 1	Homo sapiens	72-77
7849022-3	1995	This adhesion domain in human CD2 contains a single high-mannose N-glycan.	n-glycan	65-73	CD2 molecule	Homo sapiens	30-33
8043873-6	1994	In contrast, the size of the N-glycan chain on the glucose transporter (GLUT1) from MkMk cells was smaller than that on GLUT1 from normal cells.	n-glycan	29-37	solute carrier family 2 member 1	Homo sapiens	120-125
8122371-0	1994	An N-glycan within the human immunodeficiency virus type 1 gp120 V3 loop affects virus neutralization.	n-glycan	3-11	Envelope surface glycoprotein gp160, precursor	Human immunodeficiency virus 1	59-64
7520819-3	1994	RESULTS: CD59 was purified from human urine, retaining the N-glycan and at least some of the non-lipid component of the glycosylphosphatidylinositol membrane anchor.	n-glycan	59-67	CD59 molecule (CD59 blood group)	Homo sapiens	9-13
7509803-5	1994	In contrast, the N-glycan chain of the Rh glycoprotein was larger than normal in glycophorin B-deficient red cells.	n-glycan	17-25	glycophorin B (MNS blood group)	Homo sapiens	81-94
8039192-0	1994	Synthesis of tetrasaccharide analogues of the N-glycan substrate of beta-(1-->2)-N-acetylglucosaminyltransferase II using trisaccharide precursors and recombinant beta-(1-->2)-N-acetylglucosaminyltransferase I. Recombinant rabbit UDP-GlcNAc: alpha-Man-(1-->3R) beta-(1-->2)-N-acetylglucosaminyl-transferase I (EC 2.4.1.101, GlcNAc-T I) produced in the Sf9 insect cell/baculovirus expression system has been used to convert compounds of the form 3-R-alpha-Man(1-->6)(alpha-Man(1-->3)) beta-Man-O-octyl to 3-R-alpha-Man(1-->6)(beta-GlcNAc(1-->2)alpha-Man(1-->3)) beta-Man-O-octyl where R is OH (14), O-methyl (17), O-pentyl (18), O-(4,4-azo)pentyl (19), O-(5-iodoacetamido)pentyl (20) and O-(5-amino)pentyl (21); 2-deoxy-alpha-Man(1-->6)(beta-GlcNAc(1-->2) alpha-Man(1-->3)) beta-Man-O-octyl (16), 4-O-methyl-alpha-Man(1-->6) (beta-GlcNAc(1-->2) alpha-Man(1-->3)) beta-Man-O-octyl (22), 6-O-methyl-alpha-Man(1-->6)(beta-GlcNAc(1-->2) alpha Man(1-->3)) beta-Man-O-octyl (23) and alpha-Man(1-->6)[beta-GlcNAc(1-->2)(4-O-methyl) alpha-Man(1-->3)] beta-Man-O-octyl (15) were also synthesized by this procedure.	n-glycan	46-54	alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase	Homo sapiens	336-346
24178389-7	1992	Treatment of cells with tunicamycin, which inhibits N-glycosylation, and digestion of the (35)S-labelled processing intermediates with endoglycosidase H indicate that beta-1,3-glucanase has a single N-glycan attached to the C-terminal extension.	n-glycan	199-207	glucan endo-1,3-beta-glucosidase, acidic-like	Nicotiana tabacum	167-185
7693094-1	1993	The reactivity of sera from honeybee venom allergic patients with the N-glycan of phospholipase A2 was investigated using neoglycoproteins with an enzyme-linked immunosorbent assay.	n-glycan	70-78	phospholipase A2 group IB	Homo sapiens	82-98
1443615-12	1992	Hydrazinolysis proved best, with practically no loss of N-acetlylneuraminic acid and the closest resemblance to the PNGase F-derived N-glycan pool, using an automated apparatus.	n-glycan	133-141	N-glycanase 1	Homo sapiens	116-122
8019599-2	1994	To investigate the functional role of the N-glycan in band 3 (b3) we have constructed mutant b3 cDNAs in which this residue has been replaced by Gly, Ser or Thr, and the expression of these mutants was examined in Xenopus oocytes.	n-glycan	42-50	solute carrier family 4 member 1 (Diego blood group) L homeolog	Xenopus laevis	62-64
1757461-1	1991	Golgi alpha-mannosidase II (GlcNAc transferase I-dependent alpha 1,3[alpha 1,6] mannosidase, EC 3.2.1.114) catalyzes the final hydrolytic step in the N-glycan maturation pathway acting as the committed step in the conversion of high mannose to complex type structures.	n-glycan	150-158	mannosidase 2, alpha 1	Mus musculus	0-26
1560005-2	1992	Three N-linked oligosaccharides of hEPO have been partially or fully removed to obtain N-glycan (NG) (2)-, NG(1)-, and NG(0)-hEPO carrying two, one, and no N-linked sugar chains, respectively.	n-glycan	87-95	erythropoietin	Homo sapiens	35-39
1309289-3	1992	Further, peptide N-glycohydrolase F and endo-alpha-N-acetylgalactosaminidase, which are specific for the cleavage of N-glycan and O-glycan linkages, respectively, in glycoproteins were used.	n-glycan	117-125	alpha-N-acetylgalactosaminidase	Homo sapiens	45-76
1376112-6	1992	This fucose residue is present in the N-glycan of PLA2 and is frequently found in plant glycoproteins, whereas mammalian glycoproteins lack this modification.	n-glycan	38-46	phospholipase A2 group IIA	Homo sapiens	50-54
34662214-5	2022	Here, we utilize N-glycan profiling by nanoLC-chip QTOF mass cytometry to characterize the bacterial neuraminidase-associated compositional shift of the macrophage glycocalyx, which revealed a decrease in sialylated and an increase in fucosylated and high mannose structures.	n-glycan	17-25	neuraminidase 1	Homo sapiens	101-114
33767719-2	2021	Essential in animals, where a lack of complex N-glycans is embryo-lethal, their presence in plants seemed less relevant for a long time mostly because Arabidopsis thaliana cgl1 mutants lacking N-acetyl-glucosaminyltransferase I (GNTI, the enzyme initiating complex N-glycan maturation in the Golgi apparatus) are viable and showed only minor impairments regarding stress tolerance or development.	n-glycan	46-54	alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	Arabidopsis thaliana	172-176
2148533-8	1990	In conclusion, inhibition of N-glycan processing prevents iodide organification in cultured porcine thyroid cells by decreasing the recovery of cell-surface TPO activity.	n-glycan	29-37	thyroid peroxidase	Homo sapiens	157-160
2180392-4	1990	This demonstrates that gPr78gag is a N-glycan.	n-glycan	37-45	G protein-coupled receptor 78	Homo sapiens	23-28
33765222-0	2021	Interlaboratory evaluation of plasma N-glycan antennary fucosylation as a clinical biomarker for HNF1A-MODY using liquid chromatography methods.	n-glycan	37-45	HNF1 homeobox A	Homo sapiens	97-102
32890705-4	2020	METHODS: Based on our structural model, we hypothesized that GnT-V interacts with the N-glycan core or polypeptide moiety as well as the accepter site of N-glycan.	n-glycan	86-94	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	61-66
32890705-4	2020	METHODS: Based on our structural model, we hypothesized that GnT-V interacts with the N-glycan core or polypeptide moiety as well as the accepter site of N-glycan.	n-glycan	154-162	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	61-66
32890705-9	2020	CONCLUSIONS: We identified several residues involved in the action of GnT-V toward N-glycan cores and surrounding amino acids.	n-glycan	83-91	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	70-75
34662214-9	2022	Together, these findings strongly suggest that while neuraminidase-mediated N-glycan modification impaired both macrophage phagocytosis and galvanotaxis, yet to be defined mechanisms other than NanH may play a more important role in bioelectrical control of macrophage trafficking, which potentially triggers dissemination.	n-glycan	76-84	neuraminidase 1	Homo sapiens	53-66
34752419-8	2021	Consistently, N-glycosylated proteins and N-glycan biosynthesis genes were differentially expressed during metastatic BC progression, with reduced expression of EpCAM and mannose-trimming enzymes and elevated N-glycan branching and sialylation enzymes in BC metastases versus PT.	n-glycan	42-50	epithelial cell adhesion molecule	Homo sapiens	161-166
34817551-0	2021	DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis.	n-glycan	39-47	C-type lectin domain family 4, member a2	Mus musculus	0-4
34774484-4	2021	The current study explored the significance of N-glycosylation of Trop2 by substituting specific N-glycan addition sites by site-directed mutagenesis.	n-glycan	97-105	tumor associated calcium signal transducer 2	Homo sapiens	66-71
34774484-13	2021	This data suggests that site-specific N-glycan addition determines Trop2 surface density, claudin-7 interaction and exosomal release.	n-glycan	38-46	tumor associated calcium signal transducer 2	Homo sapiens	67-72
34774484-13	2021	This data suggests that site-specific N-glycan addition determines Trop2 surface density, claudin-7 interaction and exosomal release.	n-glycan	38-46	claudin 7	Homo sapiens	90-99
34817551-4	2021	Here we showed that DCIR is expressed on osteoclasts and DCs and binds to an asialo-biantennary N-glycan(s) (NA2) on bone cells and myeloid cells.	n-glycan	96-104	C-type lectin domain family 4 member A	Homo sapiens	20-24
34192302-5	2021	In this study, we analyzed site-specific N-glycan structures of serum M2BP using Glyco-RIDGE (Glycan heterogeneity-based Relational IDentification of Glycopeptide signals on Elution profile) method.	n-glycan	41-49	galectin 3 binding protein	Homo sapiens	70-74
34686894-0	2021	Apo-H (beta-2-glycoprotein) intact N-glycan analysis by MALDI-TOF-MS using sialic acid derivatization.	n-glycan	35-43	apolipoprotein H	Homo sapiens	0-5
34888356-9	2021	In particular, it was confirmed that alpha2,3-sialic acid at the terminus of biantennary N-glycan was the epitope associated with BD.	n-glycan	89-97	glycoprotein hormone subunit alpha 2	Homo sapiens	37-43
34778211-1	2021	The alpha1,6-fucosyltransferase (encoded by FUT8 gene) is the key enzyme transferring fucose to the innermost GlcNAc residue on an N-glycan through an alpha-1,6 linkage in the mammalian cells.	n-glycan	131-139	fucosyltransferase 8	Homo sapiens	4-31
34778211-1	2021	The alpha1,6-fucosyltransferase (encoded by FUT8 gene) is the key enzyme transferring fucose to the innermost GlcNAc residue on an N-glycan through an alpha-1,6 linkage in the mammalian cells.	n-glycan	131-139	fucosyltransferase 8	Homo sapiens	44-48
34375000-2	2021	The 22 N-glycan sites of Spike remain highly conserved among SARS-CoV-2 variants, opening an avenue for robust therapeutic intervention.	n-glycan	7-15	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	25-30
34778211-10	2021	The relative abundance of all the three N-glycan types (high-mannose, hybrid, and complex) was determined in FUT8KO comparing to wild-type CHO cells.	n-glycan	40-48	alpha-(1,6)-fucosyltransferase	Cricetulus griseus	109-115
34720894-14	2021	N-glycan branching on lymphocytes and oligodendroglial progenitors mediated by beta1,6-N-acetylglucosaminyltransferase V (Mgat5/GnTV) influences galectin-binding, modulating inflammatory responses and remyelination in neurodegenerative diseases.	n-glycan	0-8	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B	Homo sapiens	79-120
34720894-14	2021	N-glycan branching on lymphocytes and oligodendroglial progenitors mediated by beta1,6-N-acetylglucosaminyltransferase V (Mgat5/GnTV) influences galectin-binding, modulating inflammatory responses and remyelination in neurodegenerative diseases.	n-glycan	0-8	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	122-127
34631884-6	2021	The results of gene set enrichment analysis suggested that CKAP2L may play a regulatory role through the cell cycle, homologous recombination, and N-glycan biosynthesis cell signaling pathways.	n-glycan	147-155	cytoskeleton associated protein 2 like	Homo sapiens	59-65
34567092-2	2021	Clinical exome sequencing revealed complex alleles in ALG1, the encoding gene for the chitobiosyldiphosphodolichol beta-mannosyltransferase that participates in the formation of the dolichol-pyrophosphate-GlcNAc2Man5, a lipid-linked glycan intermediate during N-glycan synthesis.	n-glycan	260-268	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	86-139
34567092-2	2021	Clinical exome sequencing revealed complex alleles in ALG1, the encoding gene for the chitobiosyldiphosphodolichol beta-mannosyltransferase that participates in the formation of the dolichol-pyrophosphate-GlcNAc2Man5, a lipid-linked glycan intermediate during N-glycan synthesis.	n-glycan	260-268	ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase	Homo sapiens	54-58
34174425-6	2021	However, in Aspergilli, deletion of the ALG3 homolog algC leads to an N-glycan pool where the majority of the structures contain more hexose residues than the Man3-5GlcNAc2 species that can serve as substrates for humanized glycan structures.	n-glycan	70-78	dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichol alpha-1,3-mannosyltransferase	Saccharomyces cerevisiae S288C	40-44
34494836-0	2021	Dissecting the Role of N-Glycan at N413 in Toll-like Receptor 3 via Molecular Dynamics Simulations.	n-glycan	23-31	toll like receptor 3	Homo sapiens	43-63
34504130-3	2021	While the natural lectin is non-glycosylated, recombinant Orysata produced in the yeast Pichia pastoris (YOry) is modified with a hyper-mannosylated N-glycan.	n-glycan	149-157	lectin-37Db	Drosophila melanogaster	18-24
34274643-6	2021	N-Glycan analysis of the non-retained and retained AGP fractions was carried out by using PNGase F digestion and nanoflow electrospray ionization mass spectrometry.	n-glycan	0-8	N-glycanase 1	Homo sapiens	90-96
34500611-4	2021	We recently found that bisecting GlcNAc, a branching sugar in N-glycan, suppresses both GlcAT-P activity and HNK-1 expression in the brain.	n-glycan	62-70	beta-1,3-glucuronyltransferase 1	Homo sapiens	88-95
34500611-4	2021	We recently found that bisecting GlcNAc, a branching sugar in N-glycan, suppresses both GlcAT-P activity and HNK-1 expression in the brain.	n-glycan	62-70	beta-1,3-glucuronyltransferase 1	Homo sapiens	109-114
34445285-2	2021	A variety of N-glycan structures exist, of which, the formation of bisecting N-acetylglucosamine (GlcNAc) is catalyzed by N-acetylglucosaminyltransferase-III (GnT-III, encoded by the Mgat3 gene).	n-glycan	13-21	mannoside acetylglucosaminyltransferase 3	Mus musculus	183-188
34462883-0	2022	Caveolin-1 knockout mice have altered serum N-glycan profile and sialyltransferase tissue expression.	n-glycan	44-52	caveolin 1, caveolae protein	Mus musculus	0-10
34462883-4	2022	In this study, the N-glycan profiles in serum from Cav-1-/- mice were investigated by lectin microarray and mass spectrometric analysis approaches.	n-glycan	19-27	caveolin 1, caveolae protein	Mus musculus	51-56
34419057-6	2021	RESULTS: Our screen identified a sugar-specific sulfatase that specifically removes sulfate from GlcNAc-6-SO4 when it is in a terminal position on an N-glycan.	n-glycan	150-158	arylsulfatase family member H	Homo sapiens	48-57
34110173-4	2021	The newly developed Python scripts enabled the identification of 140 N-glycan compositions (237 N-glycan structures) from erythropoietin, especially including 8 phosphorylated N-glycan species.	n-glycan	69-77	erythropoietin	Homo sapiens	122-136
34110173-4	2021	The newly developed Python scripts enabled the identification of 140 N-glycan compositions (237 N-glycan structures) from erythropoietin, especially including 8 phosphorylated N-glycan species.	n-glycan	96-104	erythropoietin	Homo sapiens	122-136
34212152-4	2021	In addition, altering the tertiary structure of the glycoprotein PDI affected its N-glycan remodeling in a site-specific way.	n-glycan	82-90	prolyl 4-hydroxylase subunit beta	Homo sapiens	65-68
34163514-7	2021	Notably, N-glycan analysis revealed that a mannosidic-type N-glycan structure lacking plant-specific N-glycans (beta1,2-xylose and alpha1,3-fucose residues) was predominant in all glycosylation sites of purified GCase produced from DeltagntI plants.	n-glycan	59-67	immunoglobulin kappa variable 2D-19 (pseudogene)	Homo sapiens	112-119
34093814-2	2021	FUT8 belongs to the fucosyltransferase family and is the key enzyme involved in N-glycan core fucosylation.	n-glycan	80-88	fucosyltransferase 8	Homo sapiens	0-4
34209622-5	2021	RESULTS: We found that 12 and six IgG N-glycan traits showed significant associations with HDC in the Chinese Muslim ethnic minorities and the Han Chinese, respectively, after adjustment for potential confounders and false discovery rate.	n-glycan	38-46	histidine decarboxylase	Homo sapiens	91-94
34209622-7	2021	CONCLUSION: Altered IgG N-glycan profiles were shown to associate with HDC, suggesting the involvement of inflammatory processes of IgG glycosylation.	n-glycan	24-32	histidine decarboxylase	Homo sapiens	71-74
34495528-9	2021	N-Acetylglucosaminyltransferases (GnT-III, GnT-IV, and GnT-V) produce branched N-glycan structures, affording a higher complexity to N-glycans.	n-glycan	79-87	beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase	Homo sapiens	34-41
34495528-9	2021	N-Acetylglucosaminyltransferases (GnT-III, GnT-IV, and GnT-V) produce branched N-glycan structures, affording a higher complexity to N-glycans.	n-glycan	79-87	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B	Homo sapiens	43-49
34495528-9	2021	N-Acetylglucosaminyltransferases (GnT-III, GnT-IV, and GnT-V) produce branched N-glycan structures, affording a higher complexity to N-glycans.	n-glycan	79-87	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	55-60
34586883-13	2021	CLPTM1L related genes were enriched in protein processing in the endoplasmic reticulum, protein folding, endoplasmic reticulum formation, N-glycan biosynthesis, and protein hydroxylation.	n-glycan	138-146	CLPTM1 like	Homo sapiens	0-7
35436443-0	2022	35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope.	n-glycan	72-80	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	104-109
34522711-9	2021	The functions of CBX4 are primarily related to the stem cell pluripotency signaling pathway, Hippo signaling pathway, HTLV-I infection, Notch signaling pathway, and N-glycan biosynthesis.	n-glycan	165-173	chromobox 4	Homo sapiens	17-21
35436443-5	2022	35B5 potently neutralizes SARS-CoV-2 Omicron and other variants by causing significant conformational changes within a conserved N-glycan switch that controls the transition of RBD from the "down" state to the "up" state, which allows recognition of the host entry receptor ACE2.	n-glycan	129-137	angiotensin converting enzyme 2	Homo sapiens	274-278
35577790-4	2022	Ca2+ stabilizes the interface between two rBAT molecules, leading to super-dimerization of b0,+AT-rBAT, which in turn facilitates N-glycan maturation and protein trafficking.	n-glycan	130-138	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	42-46
35545292-3	2022	After correcting for multiple testing (p < 2 x 10-3), the standard MR analysis based on the inverse-variance weighted method showed a significant association of genetically instrumented IgG N-glycan (GP4) with RA (odds ratioGP4 = 0.906, 95% confidence interval = 0.857-0.958, p = 5.246 x 10-4).	n-glycan	190-198	CD36 molecule	Homo sapiens	200-203
35378162-13	2022	Based on the predictions made for the oligosaccharides, a tetra-antenate putative glycan was schematically constructed, illustrating an interaction between TRPA1 N-glycan and CiL-1.	n-glycan	162-170	transient receptor potential cation channel, subfamily A, member 1a	Danio rerio	156-161
35622127-5	2022	Correlation of N-glycan abundance with the levels and number of various autoantibodies (against IA-2, GAD, ZnT8R, ZnT8W), as well as with sex and age at diagnosis, were estimated by using general linear modelling.	n-glycan	15-23	glutamate decarboxylase 1	Homo sapiens	102-105
35577790-4	2022	Ca2+ stabilizes the interface between two rBAT molecules, leading to super-dimerization of b0,+AT-rBAT, which in turn facilitates N-glycan maturation and protein trafficking.	n-glycan	130-138	bile acid CoA:amino acid N-acyltransferase	Rattus norvegicus	98-102
35509261-5	2022	Here, we demonstrate that expression of a membrane-associated anti-FUT8 intrabody engineered to reside in the endoplasmic reticulum and Golgi apparatus can efficiently reduce FUT8 activity and therefore the core-fucosylation of the Fc N-glycan of an antibody.	n-glycan	235-243	alpha-(1,6)-fucosyltransferase	Cricetulus griseus	67-71
35509261-5	2022	Here, we demonstrate that expression of a membrane-associated anti-FUT8 intrabody engineered to reside in the endoplasmic reticulum and Golgi apparatus can efficiently reduce FUT8 activity and therefore the core-fucosylation of the Fc N-glycan of an antibody.	n-glycan	235-243	alpha-(1,6)-fucosyltransferase	Cricetulus griseus	175-179
35557740-3	2022	In plants, complex N-glycan modifications like the attachment of beta1,2-xylose, core alpha1,3-fucose, or the Lewis A-type structures are evolutionary highly conserved, but their biological function is poorly known.	n-glycan	19-27	immunoglobulin kappa variable 2D-19 (pseudogene)	Homo sapiens	65-72
35137040-2	2022	Glucosidase I specifically removes the distal alpha1,2-linked glucose from the protein bound precursor N-glycan Glc3Man9GlcNAc2 which is the initial step of N-glycan maturation.	n-glycan	103-111	mannosyl-oligosaccharide glucosidase	Homo sapiens	0-13
35137040-2	2022	Glucosidase I specifically removes the distal alpha1,2-linked glucose from the protein bound precursor N-glycan Glc3Man9GlcNAc2 which is the initial step of N-glycan maturation.	n-glycan	157-165	mannosyl-oligosaccharide glucosidase	Homo sapiens	0-13
35137040-5	2022	The N-glycan analysis of the serum proteome further revealed that relative intensities of IgG-specific complex type di-antennary N-glycans with core-fucosylation were considerably reduced in the patient"s serum whereas TF- and AAT-characteristic sialylated di- and tri-antennary N-glycans were increased.	n-glycan	4-12	transferrin	Homo sapiens	219-221
35406805-9	2022	Taken together, these results suggest that the N-glycan moieties of NEGR1 are closely involved in the folding, trafficking, and homodimer formation of NEGR1 protein in a site-specific manner.	n-glycan	47-55	neuronal growth regulator 1	Homo sapiens	68-73
35406805-9	2022	Taken together, these results suggest that the N-glycan moieties of NEGR1 are closely involved in the folding, trafficking, and homodimer formation of NEGR1 protein in a site-specific manner.	n-glycan	47-55	neuronal growth regulator 1	Homo sapiens	151-156
35092134-5	2022	We purified the recombinant extracellular domain of human MET and determined the site-specific N-glycan structures and occupancy using mass spectrometry.	n-glycan	95-103	SAFB like transcription modulator	Homo sapiens	58-61
35092134-7	2022	To examine the effects of the deletion of N-glycans of MET, we prepared endogenous-MET-knockout Flp-In CHO cells and transfected them with a series of N-glycan deletion mutants of MET.	n-glycan	151-159	hepatocyte growth factor receptor	Cricetulus griseus	180-183
35326703-5	2022	We used matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI) to spatially profile the N-glycan species in a cohort of pT1 CRC using archival formalin-fixed and paraffin-embedded (FFPE) material.	n-glycan	117-125	zinc finger protein 77	Homo sapiens	149-152
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	ALG3 alpha-1,3- mannosyltransferase	Homo sapiens	72-76
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	ALG9 alpha-1,2-mannosyltransferase	Homo sapiens	79-83
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	ALG11 alpha-1,2-mannosyltransferase	Homo sapiens	86-91
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	ALG12 alpha-1,6-mannosyltransferase	Homo sapiens	94-99
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	RFT1 homolog	Homo sapiens	102-106
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	steroid 5 alpha-reductase 3	Homo sapiens	109-115
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	dolichol kinase	Homo sapiens	118-122
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	Homo sapiens	125-129
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	dolichyl-phosphate mannosyltransferase subunit 3, regulatory	Homo sapiens	132-136
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	mannose-P-dolichol utilization defect 1	Homo sapiens	139-144
35279850-7	2022	Moreover, group-specific high-mannose N-glycan signatures were found in ALG3-, ALG9-, ALG11-, ALG12-, RFT1-, SRD5A3-, DOLK-, DPM1-, DPM3-, MPDU1-, ALG13-CDG, and hereditary fructose intolerance.	n-glycan	38-46	ALG13 UDP-N-acetylglucosaminyltransferase subunit	Homo sapiens	147-152
35252146-10	2022	Here, we present the first step towards sialylation of recombinant glycoproteins in Physcomitrella, human beta1,4-linked terminal N-glycan galactosylation, which was achieved by the introduction of a chimeric beta1,4-galactosyltransferase (FTGT).	n-glycan	130-138	BCL2 related protein A1	Homo sapiens	106-111
35091499-1	2022	N-glycans provide resistance to CAR T-cell therapy, and inhibition of N-glycan synthesis improves CAR efficacy.	n-glycan	70-78	CXADR pseudogene 1	Homo sapiens	32-35
35091499-1	2022	N-glycans provide resistance to CAR T-cell therapy, and inhibition of N-glycan synthesis improves CAR efficacy.	n-glycan	70-78	CXADR pseudogene 1	Homo sapiens	98-101
35104505-1	2022	N-Acetylglucosaminyltransferase-V (GnT-V or MGAT5) catalyzes the formation of an N-glycan beta1,6-GlcNAc branch on selective target proteins in the Golgi apparatus and is involved in cancer malignancy and autoimmune disease etiology.	n-glycan	81-89	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	0-33
35104505-1	2022	N-Acetylglucosaminyltransferase-V (GnT-V or MGAT5) catalyzes the formation of an N-glycan beta1,6-GlcNAc branch on selective target proteins in the Golgi apparatus and is involved in cancer malignancy and autoimmune disease etiology.	n-glycan	81-89	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	35-40
35104505-1	2022	N-Acetylglucosaminyltransferase-V (GnT-V or MGAT5) catalyzes the formation of an N-glycan beta1,6-GlcNAc branch on selective target proteins in the Golgi apparatus and is involved in cancer malignancy and autoimmune disease etiology.	n-glycan	81-89	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	44-49
34981577-0	2022	O-GlcNAcylation regulates beta1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis.	n-glycan	50-58	O-linked N-acetylglucosamine (GlcNAc) transferase	Homo sapiens	80-83
34981577-0	2022	O-GlcNAcylation regulates beta1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis.	n-glycan	50-58	solute carrier family 35 member A3	Homo sapiens	84-91
34981577-0	2022	O-GlcNAcylation regulates beta1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV axis.	n-glycan	50-58	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A	Homo sapiens	92-98
35044789-0	2022	Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies.	n-glycan	11-19	nuclear receptor subfamily 1 group I member 3	Homo sapiens	53-78
35014832-7	2022	Second, we compared the effects of single amino acid substitution at the N-sequons, including N186Q, N343Q, and N352Q, each one N-glycan reduction from one NEU1 molecule.	n-glycan	128-136	neuraminidase 1	Homo sapiens	156-160
35014832-14	2022	The third N-glycan at the N352-sequon contributes to the self-aggregation of NEU1.	n-glycan	10-18	neuraminidase 1	Homo sapiens	77-81
35011724-6	2022	We hereby highlighted that N-glycan functions by preventing the oligomerization of 4-1BB, thus permitting its membrane transportation and fast turn-over.	n-glycan	27-35	TNF receptor superfamily member 9	Homo sapiens	83-88