PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 17573462-4 2007 Administration of glucosamine (10 mM) or an inhibitor of O-GlcNAcase, O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc; 200 microM), during the first 20 min of reperfusion significantly improved cardiac functional recovery and reduced troponin release during reperfusion compared with untreated control. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 70-138 O-GlcNAcase Rattus norvegicus 57-68 16365142-7 2006 Conversely, treatment with the beta-N-acetylglucosaminidase inhibitor, O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate, in the presence of normal glucose increased Sp1 O-GlcNAcylation and PAI-1 mRNA and protein levels. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 71-139 O-GlcNAcase Homo sapiens 31-59 17142462-9 2007 Consistent with this observation, inhibition of N-acetylglucosaminidase, the enzyme involved in the removal of the O-GlcNAc modification from proteins, with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate stimulates MafA expression under low glucose conditions. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 157-225 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 115-123 17142462-9 2007 Consistent with this observation, inhibition of N-acetylglucosaminidase, the enzyme involved in the removal of the O-GlcNAc modification from proteins, with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate stimulates MafA expression under low glucose conditions. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 157-225 MAF bZIP transcription factor A Homo sapiens 237-241 16365142-7 2006 Conversely, treatment with the beta-N-acetylglucosaminidase inhibitor, O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate, in the presence of normal glucose increased Sp1 O-GlcNAcylation and PAI-1 mRNA and protein levels. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 71-139 serpin family E member 1 Homo sapiens 209-214 15843043-4 2005 Treating cells with either 8 mM d-glucosamine (GlcN), 5 mM streptozotocin (STZ), or 80 muM O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc) produced a significant increase in the O-GlcNAc modification on both cytosolic and membrane proteins; however, both the level and rate of O-GlcNAc increase varied with the compound. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 91-159 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 208-216 15843043-4 2005 Treating cells with either 8 mM d-glucosamine (GlcN), 5 mM streptozotocin (STZ), or 80 muM O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc) produced a significant increase in the O-GlcNAc modification on both cytosolic and membrane proteins; however, both the level and rate of O-GlcNAc increase varied with the compound. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 91-159 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 307-315 11959983-3 2002 Cycling of the O-GlcNAc posttranslational modification was blocked by pharmacological inhibition of O-GlcNAcase, the enzyme that catalyzes O-GlcNAc removal from proteins, with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc). o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 176-244 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 15-23 11959983-3 2002 Cycling of the O-GlcNAc posttranslational modification was blocked by pharmacological inhibition of O-GlcNAcase, the enzyme that catalyzes O-GlcNAc removal from proteins, with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc). o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 176-244 O-GlcNAcase Homo sapiens 100-111 11959983-3 2002 Cycling of the O-GlcNAc posttranslational modification was blocked by pharmacological inhibition of O-GlcNAcase, the enzyme that catalyzes O-GlcNAc removal from proteins, with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc). o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 176-244 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 100-108 15703172-3 2005 Here, we extend this correlation by showing that a mechanistically distinct means of increasing O-GlcNAc, achieved by inhibition of O-GlcNAc removal with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc), increases basal cellular motility and directional migration induced by the chemoattractant formyl-methionine-leucine-phenylalanine (fMLP). o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 154-222 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 96-104 15703172-3 2005 Here, we extend this correlation by showing that a mechanistically distinct means of increasing O-GlcNAc, achieved by inhibition of O-GlcNAc removal with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc), increases basal cellular motility and directional migration induced by the chemoattractant formyl-methionine-leucine-phenylalanine (fMLP). o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 154-222 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 132-140 15703172-3 2005 Here, we extend this correlation by showing that a mechanistically distinct means of increasing O-GlcNAc, achieved by inhibition of O-GlcNAc removal with O-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc), increases basal cellular motility and directional migration induced by the chemoattractant formyl-methionine-leucine-phenylalanine (fMLP). o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 154-222 formyl peptide receptor 1 Homo sapiens 365-369 9452489-0 1998 Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-beta-N-acetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate. o-(2-acetamido-2-deoxy-d-glucopyranosylidene)amino-n-phenylcarbamate 160-228 O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens 112-120