PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
18326070-0	2008	1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors.	1-(1-arylethylidene)thiosemicarbazide	0-37	tyrosinase	Homo sapiens	66-76
18326070-1	2008	A series of 1-(1-arylethylidene)thiosemicarbazide compounds and their analogues were synthesized and characterized by 1H NMR, MS. Their tyrosinase inhibitory activities were investigated by an assay based on the catalyzing ability of tyrosinase for the oxidation of L-DOPA, comparing with 4-methoxycinnamic acid and arbutin.	1-(1-arylethylidene)thiosemicarbazide	12-49	tyrosinase	Homo sapiens	136-146
18326070-1	2008	A series of 1-(1-arylethylidene)thiosemicarbazide compounds and their analogues were synthesized and characterized by 1H NMR, MS. Their tyrosinase inhibitory activities were investigated by an assay based on the catalyzing ability of tyrosinase for the oxidation of L-DOPA, comparing with 4-methoxycinnamic acid and arbutin.	1-(1-arylethylidene)thiosemicarbazide	12-49	tyrosinase	Homo sapiens	234-244