PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 18336853-6 2008 In comparison, 10(-7) to 2 x 10(-5) M PNMPP with 1 mM 8-Br-cAMP for 48 h decreased concentrations of estradiol-17beta, increased progesterone levels, but did not affect testosterone and cortisol secretion due to the significant suppression of CYP17 and the non-significant but obvious suppression of CYP19. pnmpp 38-43 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 243-248 18439640-12 2008 These results clearly indicate that PNMC and PNMPP do not show genotoxicity but act as tumor promoters in an estrogen receptor alpha-predominant breast cancer cell line. pnmpp 45-50 estrogen receptor 1 Homo sapiens 109-132 18336853-6 2008 In comparison, 10(-7) to 2 x 10(-5) M PNMPP with 1 mM 8-Br-cAMP for 48 h decreased concentrations of estradiol-17beta, increased progesterone levels, but did not affect testosterone and cortisol secretion due to the significant suppression of CYP17 and the non-significant but obvious suppression of CYP19. pnmpp 38-43 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 300-305