PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 18990571-1 2008 A series of 2-substituted-1,3,4-thiadiazole-5-sulfamides was prepared and assayed as inhibitors of several carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the cytosolic CA I and II, the membrane-associated CA IV and the mitochondrial CA VA and VB. 2-substituted-1,3,4-thiadiazole-5-sulfamides 12-56 carbonic anhydrase 1 Homo sapiens 167-178 18990571-1 2008 A series of 2-substituted-1,3,4-thiadiazole-5-sulfamides was prepared and assayed as inhibitors of several carbonic anhydrase (CA, EC 4.2.1.1) isoforms, the cytosolic CA I and II, the membrane-associated CA IV and the mitochondrial CA VA and VB. 2-substituted-1,3,4-thiadiazole-5-sulfamides 12-56 carbonic anhydrase 5A Homo sapiens 232-237