PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 21136982-0 2009 Characterisation of flucloxacillin and 5-hydroxymethyl flucloxacillin haptenated HSA in vitro and in vivo. 5-hydroxymethylflucloxacillin 39-69 albumin Homo sapiens 81-84 11409940-8 2001 Supernatants from both liver microsome and CYP3A4 preparations contained one major metabolite which was identified as 5"-hydroxymethylflucloxacillin. 5-hydroxymethylflucloxacillin 118-148 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 43-49 11409940-12 2001 In conclusion, hepatocytes mainly via CYP3A4 activity, generate flucloxacillin metabolite(s) including 5"-hydroxymethylflucloxacillin that may induce cytotoxicity in susceptible BEC. 5-hydroxymethylflucloxacillin 103-133 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 38-44