PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
19571395-5	2009	Pyripyropenes were originally isolated as an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT-2).	pyripyropenes	0-13	acetyl-CoA acetyltransferase 2	Homo sapiens	97-103
8982344-4	1996	Replacement of the 1,11-acyl groups of pyripyropenes with 1,11-cyclic acetals effectively improved in vitro acyl CoA:cholesterol acyltransferase (ACAT) inhibitory activity.	pyripyropenes	39-52	sterol O-acyltransferase 1	Homo sapiens	108-144
8982344-4	1996	Replacement of the 1,11-acyl groups of pyripyropenes with 1,11-cyclic acetals effectively improved in vitro acyl CoA:cholesterol acyltransferase (ACAT) inhibitory activity.	pyripyropenes	39-52	sterol O-acyltransferase 1	Homo sapiens	146-150