PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 19571395-5 2009 Pyripyropenes were originally isolated as an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT-2). pyripyropenes 0-13 acetyl-CoA acetyltransferase 2 Homo sapiens 97-103 8982344-4 1996 Replacement of the 1,11-acyl groups of pyripyropenes with 1,11-cyclic acetals effectively improved in vitro acyl CoA:cholesterol acyltransferase (ACAT) inhibitory activity. pyripyropenes 39-52 sterol O-acyltransferase 1 Homo sapiens 108-144 8982344-4 1996 Replacement of the 1,11-acyl groups of pyripyropenes with 1,11-cyclic acetals effectively improved in vitro acyl CoA:cholesterol acyltransferase (ACAT) inhibitory activity. pyripyropenes 39-52 sterol O-acyltransferase 1 Homo sapiens 146-150