PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3061383-5 1988 Strains producing Oxa-1 and chromosomal beta-lactamases usually where highly susceptible to mecillinam but only moderately sensitive or resistant to the combination of amoxicillin/clavulanic acid. Amoxicillin 168-179 beta-lactamase OXA-1 precursor Escherichia coli 18-23 3190988-7 1988 The mean values of dialysis clearance, total serum clearance during dialysis, fractional drug removal during haemodialysis and half-life during dialysis for amoxycillin were 77.1 ml min-1, 91.5 ml min-1, 0.64 and 2.30 h, respectively. Amoxicillin 157-168 CD59 molecule (CD59 blood group) Homo sapiens 197-202 2606820-1 1989 Clavulanic acid is known to potentiate the activity of amoxycillin and ticarcillin against beta-lactamase-producing Bacteroides species. Amoxicillin 55-66 beta-lactamase Escherichia coli 91-105 2606821-3 1989 The presence of beta-lactamase was related to inactivation of amoxycillin in the lung secretions. Amoxicillin 62-73 beta-lactamase TEM-1 Haemophilus influenzae 16-30 3190988-5 1988 The mean values of total serum clearance, mean residence time, volume of distribution at steady state, and terminal half-life for amoxycillin on the non-dialysis day were 14.4 ml min-1, 19.2 h, 14.9 l and 13.6 h, respectively. Amoxicillin 130-141 CD59 molecule (CD59 blood group) Homo sapiens 179-184 3190988-7 1988 The mean values of dialysis clearance, total serum clearance during dialysis, fractional drug removal during haemodialysis and half-life during dialysis for amoxycillin were 77.1 ml min-1, 91.5 ml min-1, 0.64 and 2.30 h, respectively. Amoxicillin 157-168 CD59 molecule (CD59 blood group) Homo sapiens 182-187 3147528-1 1988 Antibiotics available to treat uncomplicated anogenital infections due to beta-lactamase-producing Neisseria gonorrhoeae include spectinomycin, ceftriaxone, and clavulanic acid added to aqueous procaine penicillin G or amoxicillin. Amoxicillin 219-230 beta-lactamase Neisseria gonorrhoeae 74-88 3263350-5 1988 Amoxycillin and ampicillin induced more beta-lactamase than the inhibitors, but were much less effective than cefoxitin, except for the strain of Prov. Amoxicillin 0-11 beta-lactamase Providencia rettgeri 40-54 3061383-0 1988 In vitro activity of mecillinam and amoxicillin/clavulanic acid against strains of Escherichia coli producing TEM-1, Oxa-1 and chromosomal beta-lactamases. Amoxicillin 36-47 hypothetical protein Escherichia coli 110-115 3061383-0 1988 In vitro activity of mecillinam and amoxicillin/clavulanic acid against strains of Escherichia coli producing TEM-1, Oxa-1 and chromosomal beta-lactamases. Amoxicillin 36-47 beta-lactamase OXA-1 precursor Escherichia coli 117-122 3265293-7 1988 The production of beta-lactamase prevented the use of amoxicillin. Amoxicillin 54-65 beta-lactamase TEM-1 Haemophilus influenzae 18-32 3263690-8 1988 Synergy between clavulanate or sulbactam (2 micrograms/mL) and amoxicillin was greater against derivatives producing EBS-Bla than against those producing TEM-1, TEM-2, or SHV-1; this synergy was greater with clavulanate than with sulbactam against derivatives producing SHV-2 and the SHV-2-type enzyme but was similar with clavulanate and sulbactam against those producing CTX-1. Amoxicillin 63-74 beta-lactamase Escherichia coli 121-124 3263690-8 1988 Synergy between clavulanate or sulbactam (2 micrograms/mL) and amoxicillin was greater against derivatives producing EBS-Bla than against those producing TEM-1, TEM-2, or SHV-1; this synergy was greater with clavulanate than with sulbactam against derivatives producing SHV-2 and the SHV-2-type enzyme but was similar with clavulanate and sulbactam against those producing CTX-1. Amoxicillin 63-74 hypothetical protein Escherichia coli 154-159 3467190-0 1986 [Pharmacokinetic analyses of the absorption of ampicillin and amoxicillin into the blood and experimentally infected skin after simultaneous administration of an antibiotic with bromelain and lysozyme]. Amoxicillin 62-73 lysozyme Homo sapiens 192-200 3617467-1 1987 The blood level and the basic pharmacokinetic parameters (kel, Cop, T 1/2, AUC) of amoxicillin trihydrate were studied following its oral application to albino rats with experimentally injured kidneys (potassium chromate) and liver (tetrachloromethane). Amoxicillin 83-105 brachyury 2 Rattus norvegicus 68-78 3488425-6 1986 Against E. coli and K. pneumoniae, the activity of BRL 25000 was superior to that of AMPC and approximately equal to CEX, CDX and CXD but 2-fold less than CCL. Amoxicillin 85-89 bromodomain containing 1 Homo sapiens 51-54 3891282-1 1985 Potassium clavulanate is a novel beta-lactamase inhibitor, which, in combination, expands the spectrum of amoxicillin to include many amoxicillin-resistant organisms. Amoxicillin 106-117 beta-lactamase TEM-1 Haemophilus influenzae 33-47 3875310-9 1985 The combination of amoxicillin plus potassium clavulanate appears to be an excellent drug for treatment of beta-lactamase-producing strains of these two species, although mild gastrointestinal side effects are common. Amoxicillin 19-30 beta-lactamase TEM-1 Haemophilus influenzae 107-121 3924814-3 1985 Penicillinase (beta lactamase) producing strains of Neisseria gonorrhoeae (PPNG) were found in 23 (10.5%) patients, of whom 10 were treated with Augmentin and 13 with amoxycillin. Amoxicillin 167-178 beta-lactamase Neisseria gonorrhoeae 0-29 3891282-1 1985 Potassium clavulanate is a novel beta-lactamase inhibitor, which, in combination, expands the spectrum of amoxicillin to include many amoxicillin-resistant organisms. Amoxicillin 134-145 beta-lactamase TEM-1 Haemophilus influenzae 33-47 6365790-2 1983 Apart from one E. coli, the strains were highly resistant to amoxicillin due to beta-lactamase production. Amoxicillin 61-72 beta-lactamase Escherichia coli 80-94 3847521-2 1985 The antibacterial activities of BRL 25000 and amoxicillin (AMPC) were investigated against clinically isolated and laboratory stocked strains. Amoxicillin 46-57 beta-lactamase Escherichia coli 59-63 3847525-0 1985 [Effect of BRL 25000 (clavulanic acid-amoxicillin) on bacterial flora in human feces]. Amoxicillin 38-49 bromodomain containing 1 Homo sapiens 11-14 4007254-1 1985 The pharmacokinetics of amoxycillin in the CSF following intravenous and oral administration at a 150 mg/kg per day or 250 mg/kg per day dosage in the treatment of purulent meningitis is described. Amoxicillin 24-35 colony stimulating factor 2 Homo sapiens 43-46 4007254-2 1985 A significant correlation between meningeal inflammation and CSF levels of amoxycillin were observed, including a correlation between the initial neurological state and the outcome of the illness. Amoxicillin 75-86 colony stimulating factor 2 Homo sapiens 61-64 6611533-1 1984 This study compares the probability of in vitro activity of amoxicillin-clavulanic acid combination (AMOX-CLA) with those of amoxicillin (AMOX), cephalothin (CEPH), cotrimoxazole (COT) and nalidixic acid (NAL) on the 2 003 strains isolated during the first semester of 1983 in 5 wards of medicine (MED), 2 of gynecology-obstetrics (GYN) and 1 of pediatrics (PED) at the Pitie-Salpetriere Hospital. Amoxicillin 60-71 selectin P ligand Homo sapiens 106-109 6611533-1 1984 This study compares the probability of in vitro activity of amoxicillin-clavulanic acid combination (AMOX-CLA) with those of amoxicillin (AMOX), cephalothin (CEPH), cotrimoxazole (COT) and nalidixic acid (NAL) on the 2 003 strains isolated during the first semester of 1983 in 5 wards of medicine (MED), 2 of gynecology-obstetrics (GYN) and 1 of pediatrics (PED) at the Pitie-Salpetriere Hospital. Amoxicillin 101-105 selectin P ligand Homo sapiens 106-109 6611533-2 1984 As expected, AMOX-CLA was active on most of the strains of S. aureus, E. coli, P. mirabilis, Klebsiella and Bacteroides resistant to AMOX. Amoxicillin 13-17 selectin P ligand Homo sapiens 18-21 6611533-3 1984 AMOX-CLA was active on 70 to 86% of all strains, a higher rate than that of AMOX in all situations taken in concert. Amoxicillin 0-4 selectin P ligand Homo sapiens 5-8 6611533-7 1984 Therefore, AMOX-CLA was superior to AMOX in every case, and comparable to CEPH and often COT and NAL, whose use is restricted in pregnant women and neonates owing to side effects. Amoxicillin 11-15 selectin P ligand Homo sapiens 16-19 3897971-1 1985 Results of conventional techniques indicate that most non-beta-lactamase producing Haemophilus influenzae strains are "susceptible" to ampicillin and amoxicillin. Amoxicillin 150-161 beta-lactamase TEM-1 Haemophilus influenzae 58-72 6606223-5 1983 Twenty amoxycillin-resistant beta-lactamase non-producing strains showed high MICs for all beta-lactams tested. Amoxicillin 7-18 beta-lactamase TEM-1 Haemophilus influenzae 29-43 6876360-1 1983 BRL 25000, consisting of 250 mg amoxicillin (AMPC) and 125 mg clavulanic acid (CVA), was studied in the field of obstetrics and gynecology. Amoxicillin 32-43 bromodomain containing 1 Homo sapiens 0-3 6876360-1 1983 BRL 25000, consisting of 250 mg amoxicillin (AMPC) and 125 mg clavulanic acid (CVA), was studied in the field of obstetrics and gynecology. Amoxicillin 45-49 bromodomain containing 1 Homo sapiens 0-3 33955239-5 2021 Results: The study included 60 RA and 269 ax-SpA patients. Amoxicillin 42-44 surfactant protein A1 Homo sapiens 45-48 6289230-4 1982 Pharmacologically, after a same dose of 50mg/kg the peak concentrations in CSF has the same level: CFTRX: 6.8 micrograms/ml, AMOX: 6 micrograms/ml. Amoxicillin 125-129 colony stimulating factor 2 Homo sapiens 75-78 6289230-5 1982 CSF levels remain efficient for 2 hours with AMOX and for 24 hours with CFTRX. Amoxicillin 45-49 colony stimulating factor 2 Homo sapiens 0-3 6289230-6 1982 The therapeutic index (mean antibiotic concentration in CSF/mean MIC of the strains) is higher with CFTRX than with AMOX (X 4 for pneumococci, X 15 for H. influenzae, X 100 for meningococci). Amoxicillin 116-120 colony stimulating factor 2 Homo sapiens 56-59 742877-2 1978 Serum and CSF concentrations of amoxicillin were measured at 2 h in nine patients who received a 1-g oral dose and at 1.5 and 4 h in ten patients who received a 2-g intravenous injection of sodium amoxicillin. Amoxicillin 32-43 colony stimulating factor 2 Homo sapiens 10-13 742877-4 1978 After the intravenous injection, CSF concentrations ranged from 2.9 to 40.0 mug/ml at 1.5 h and from 2.6 to 27.0 mug/ml at 4 h. These data on penetration suggest that parenterally administered sodium amoxicillin may be of value in the therapy of acute bacterial meningitis. Amoxicillin 193-211 colony stimulating factor 2 Homo sapiens 33-36 6460978-9 1982 In dogs with healthy meninges the CSF/serum AUC ratios were 0.52 % with amoxycillin, 0.75 % with cefuroxime, 1.05 % with cefamandole, 1.18 % with cefoxitin and 3.6 % with cefotaxime. Amoxicillin 72-83 colony stimulating factor 2 Canis lupus familiaris 34-37 33341100-4 2021 The method is linear over the concentration ranges of 100.0-1000.0 ng/mL for amoxicillin and 2.0-20.0 ng/mL for ethopabate. Amoxicillin 77-88 thrombopoietin Mus musculus 70-72 33955239-6 2021 At month 24, the retention rates were 67.2 and 57.1% (biologic-naive and biologic-experienced RA) and 74.8 and 80.4% (anti-TNF-naive and -experienced ax-SpA). Amoxicillin 150-152 tumor necrosis factor Homo sapiens 123-126 33955239-6 2021 At month 24, the retention rates were 67.2 and 57.1% (biologic-naive and biologic-experienced RA) and 74.8 and 80.4% (anti-TNF-naive and -experienced ax-SpA). Amoxicillin 150-152 surfactant protein A1 Homo sapiens 153-156 33341955-4 2021 The coadministration of tegoprazan with amoxicillin/clarithromycin increased Css,max (2.2-fold) and AUCtau (2.7-fold) of tegoprazan and M1 (2.1- and 2.2-fold for Css,max and AUCtau , respectively) compared to administration of tegoprazan alone. Amoxicillin 40-51 cytidine monophosphate N-acetylneuraminic acid synthetase Homo sapiens 77-80 33909178-4 2021 Ax PsA appears to be distinct from ankylosing spondylitis in demographic, clinical, genetic and therapeutic features. Amoxicillin 0-2 aminopeptidase puromycin sensitive Homo sapiens 3-6 33576040-7 2021 Moreover, the four compounds were found to be less active and safer against hIMPDH2 than the reference drugs, with IC50 > 17.17 microM, which makes sure that their selectivity is toward HpIMPDH and reverse to that of amoxicillin and clarithromycin. Amoxicillin 218-229 inosine monophosphate dehydrogenase 2 Homo sapiens 76-83 33314714-8 2021 Therapeutically relevant concentrations of AMX (>=2 microg mL-1 ), LD (>=0.5 microg mL-1 ), and LVX (>=0.2 microg mL-1 ) are successfully achieved at 1, 2, and 1 h, respectively. Amoxicillin 43-46 L1 cell adhesion molecule Mus musculus 59-63 33190311-8 2021 The mRNA expressions of TNF-alpha, iNOS and COX-2 were upregulated by PCA-AX-L and downregulated by PCA-AX-K in dose-dependent manner. Amoxicillin 74-76 tumor necrosis factor Mus musculus 24-33 33190311-8 2021 The mRNA expressions of TNF-alpha, iNOS and COX-2 were upregulated by PCA-AX-L and downregulated by PCA-AX-K in dose-dependent manner. Amoxicillin 104-106 tumor necrosis factor Mus musculus 24-33 33190311-9 2021 Furthermore, in western blotting, the ERK and NF-kappaB were found to be activated by PCA-AX-L and inhibited by PCA-AX-K. Our findings suggest that the high branched arabinoxylans of PCA-AX-L could modulate the immune response in RAW 264.7 cells through activation of ERK and NF-kappaB signaling pathways and acts as an immunostimulant. Amoxicillin 90-92 mitogen-activated protein kinase 1 Mus musculus 38-41 33190311-9 2021 Furthermore, in western blotting, the ERK and NF-kappaB were found to be activated by PCA-AX-L and inhibited by PCA-AX-K. Our findings suggest that the high branched arabinoxylans of PCA-AX-L could modulate the immune response in RAW 264.7 cells through activation of ERK and NF-kappaB signaling pathways and acts as an immunostimulant. Amoxicillin 116-118 mitogen-activated protein kinase 1 Mus musculus 38-41 33190311-9 2021 Furthermore, in western blotting, the ERK and NF-kappaB were found to be activated by PCA-AX-L and inhibited by PCA-AX-K. Our findings suggest that the high branched arabinoxylans of PCA-AX-L could modulate the immune response in RAW 264.7 cells through activation of ERK and NF-kappaB signaling pathways and acts as an immunostimulant. Amoxicillin 116-118 mitogen-activated protein kinase 1 Mus musculus 38-41 33190311-10 2021 The higher phenolic content in PCA-AX-K could modulate the immune response by downregulation of ERK and NF-kappaB signaling pathways and thus, it could act as an immunomodulator. Amoxicillin 35-37 mitogen-activated protein kinase 1 Mus musculus 96-99 33751238-1 2021 OBJECTIVES: The aim is to explore the optimal drug dose and duration of adjunctive Amoxicillin-plus-Metronidazole (AMX/MET) to full-mouth scaling and planing (FMSRP) in periodontitis. Amoxicillin 83-94 SAFB like transcription modulator Homo sapiens 115-122 33341955-4 2021 The coadministration of tegoprazan with amoxicillin/clarithromycin increased Css,max (2.2-fold) and AUCtau (2.7-fold) of tegoprazan and M1 (2.1- and 2.2-fold for Css,max and AUCtau , respectively) compared to administration of tegoprazan alone. Amoxicillin 40-51 cytidine monophosphate N-acetylneuraminic acid synthetase Homo sapiens 162-165 33226983-13 2020 CONCLUSIONS: In this study, we observed that the increased risk of CV events with clarithromycin compared with amoxicillin was associated with an interaction with P-glycoprotein. Amoxicillin 111-122 ATP binding cassette subfamily B member 1 Homo sapiens 163-177 32777075-0 2020 HLA DRB1*15:01-DQB1*06:02-restricted human CD4+ T-cells are selectively activated with amoxicillin-peptide adducts. Amoxicillin 87-98 major histocompatibility complex, class II, DR beta 1 Homo sapiens 0-8 33054207-4 2020 Consequently, two CO and C2H4 molecules coordinate with 1 at the Rh-Ax and Rh-Eq sites to afford trigonal bipyramidal complexes Rh(PAlP)(CO)2 and Rh(PAlP)(C2H4)2, which is consistent with the experimental observation of Rh(PAlP)(CO)2. Amoxicillin 68-70 alkaline phosphatase, placental Homo sapiens 131-135 33054207-4 2020 Consequently, two CO and C2H4 molecules coordinate with 1 at the Rh-Ax and Rh-Eq sites to afford trigonal bipyramidal complexes Rh(PAlP)(CO)2 and Rh(PAlP)(C2H4)2, which is consistent with the experimental observation of Rh(PAlP)(CO)2. Amoxicillin 68-70 alkaline phosphatase, placental Homo sapiens 149-153 32777075-0 2020 HLA DRB1*15:01-DQB1*06:02-restricted human CD4+ T-cells are selectively activated with amoxicillin-peptide adducts. Amoxicillin 87-98 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 15-19 32777075-0 2020 HLA DRB1*15:01-DQB1*06:02-restricted human CD4+ T-cells are selectively activated with amoxicillin-peptide adducts. Amoxicillin 87-98 CD4 molecule Homo sapiens 43-46 32777075-6 2020 This study aimed to (1) investigate whether amoxicillin-modified HLA-DRB1*15:01-DQB1*06:02 binding peptides selectively activate DILI patient T-cells and (2) define the nature of the T-cell response with respective to antigen structure. Amoxicillin 44-55 major histocompatibility complex, class II, DR beta 1 Homo sapiens 65-73 32777075-6 2020 This study aimed to (1) investigate whether amoxicillin-modified HLA-DRB1*15:01-DQB1*06:02 binding peptides selectively activate DILI patient T-cells and (2) define the nature of the T-cell response with respective to antigen structure. Amoxicillin 44-55 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 80-84 32777075-10 2020 Amoxicillin-modified KP-2 and KP-3 peptide-specific CD4+ clones proliferated and secreted IFN-gamma, IL-10, perforin and/or IL-17/IL-22 in a dose-dependent manner and displayed no cross-reactivity with amoxicillin, unmodified peptide or with positional derivatives. Amoxicillin 0-11 CD4 molecule Homo sapiens 52-55 32777075-10 2020 Amoxicillin-modified KP-2 and KP-3 peptide-specific CD4+ clones proliferated and secreted IFN-gamma, IL-10, perforin and/or IL-17/IL-22 in a dose-dependent manner and displayed no cross-reactivity with amoxicillin, unmodified peptide or with positional derivatives. Amoxicillin 0-11 interferon gamma Homo sapiens 90-99 32485627-4 2020 The BET-specific surface area of the catalyst reduced after AMX removal from 4.4 m2/g to 3.6 m2/g. Amoxicillin 60-63 delta/notch like EGF repeat containing Homo sapiens 4-7 32777075-10 2020 Amoxicillin-modified KP-2 and KP-3 peptide-specific CD4+ clones proliferated and secreted IFN-gamma, IL-10, perforin and/or IL-17/IL-22 in a dose-dependent manner and displayed no cross-reactivity with amoxicillin, unmodified peptide or with positional derivatives. Amoxicillin 0-11 interleukin 10 Homo sapiens 101-106 32777075-10 2020 Amoxicillin-modified KP-2 and KP-3 peptide-specific CD4+ clones proliferated and secreted IFN-gamma, IL-10, perforin and/or IL-17/IL-22 in a dose-dependent manner and displayed no cross-reactivity with amoxicillin, unmodified peptide or with positional derivatives. Amoxicillin 0-11 interleukin 17A Homo sapiens 124-129 32777075-10 2020 Amoxicillin-modified KP-2 and KP-3 peptide-specific CD4+ clones proliferated and secreted IFN-gamma, IL-10, perforin and/or IL-17/IL-22 in a dose-dependent manner and displayed no cross-reactivity with amoxicillin, unmodified peptide or with positional derivatives. Amoxicillin 0-11 interleukin 22 Homo sapiens 130-135 32777075-10 2020 Amoxicillin-modified KP-2 and KP-3 peptide-specific CD4+ clones proliferated and secreted IFN-gamma, IL-10, perforin and/or IL-17/IL-22 in a dose-dependent manner and displayed no cross-reactivity with amoxicillin, unmodified peptide or with positional derivatives. Amoxicillin 202-213 CD4 molecule Homo sapiens 52-55 32777075-11 2020 The T-cells response was HLA class II-restricted and the amoxicillin-modified peptides bound selectively to HLA-DRB1*15:01 and/or DQB1*06:02. Amoxicillin 57-68 major histocompatibility complex, class II, DR beta 1 Homo sapiens 108-116 32777075-11 2020 The T-cells response was HLA class II-restricted and the amoxicillin-modified peptides bound selectively to HLA-DRB1*15:01 and/or DQB1*06:02. Amoxicillin 57-68 major histocompatibility complex, class II, DQ beta 1 Homo sapiens 130-134 32777075-12 2020 To conclude, we show that amoxicillin-modified peptides bind to both components of the risk haplotype to stimulate DILI patient T-cells and describe the importance of the position of nucleophilic lysine residue in the HLA binding peptide sequence. Amoxicillin 26-37 major histocompatibility complex, class II, DR beta 1 Homo sapiens 218-221 32713104-0 2020 Searching for an optimal therapy for H pylori eradication: High-dose proton-pump inhibitor dual therapy with amoxicillin vs. standard triple therapy for 14 days. Amoxicillin 109-120 ATPase H+/K+ transporting subunit alpha Homo sapiens 69-80 33192526-7 2020 Doxycycline, amoxicillin, and trimethoprim-sulfamethoxazole were the most frequently consumed antibiotics during these years, accounting for 20.01, 16.75, and 12.42 DDD/1,000/D, respectively. Amoxicillin 13-24 keratin 5 Homo sapiens 165-176 32428691-4 2020 Data to be collected at the initial systematic review comprised 5 patient"s self-administered questionnaires, 3 variables of the physician"s interview, 2 variables of the physical examination, 2 variables of the specific ax-SpA imaging and 2 other investigations. Amoxicillin 221-223 surfactant protein A1 Homo sapiens 224-227 32428691-6 2020 CONCLUSIONS: Using an evidence-based and an expert consensus approaches, this initiative defined a core set of variables to be collected and reported right after the diagnosis and during follow-up of patients with ax-SpA in daily practice. Amoxicillin 214-216 surfactant protein A1 Homo sapiens 217-220 32690159-12 2020 A different distribution of the constant (b) for each group was observed for each BCAA correlation when a in the regression line (Y = aX + b) was fixed at the value for Group C, and b was calculated. Amoxicillin 134-136 AT-rich interaction domain 4B Homo sapiens 82-86 33110448-2 2020 Proton pump inhibitor-amoxicillin-containing high dose dual therapy (HDDT) has been proposed to treat H. pylori infection. Amoxicillin 22-33 ATPase H+/K+ transporting subunit alpha Homo sapiens 0-11 32764931-4 2020 The AMX@MWCNTs were then chemically grafted onto the surfaces of the PCL/SF nanofibers by treating with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide/N-hydroxysuccinimide (EDC/NHS) solution for simultaneous crosslinking and coating. Amoxicillin 4-7 hepatocyte growth factor Rattus norvegicus 69-75 32680971-0 2020 Small molecule AX-024 targets T cell receptor signaling by disrupting CD3epsilon-Nck interaction. Amoxicillin 15-17 CD3 epsilon subunit of T-cell receptor complex Homo sapiens 70-80 32680971-0 2020 Small molecule AX-024 targets T cell receptor signaling by disrupting CD3epsilon-Nck interaction. Amoxicillin 15-17 NCK adaptor protein 1 Homo sapiens 81-84 32626909-14 2020 Amoxicillin decreased KLK4 and CLDN1, CLDN4 and OCLN expression in mature ameloblasts. Amoxicillin 0-11 kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) Mus musculus 22-26 32626909-14 2020 Amoxicillin decreased KLK4 and CLDN1, CLDN4 and OCLN expression in mature ameloblasts. Amoxicillin 0-11 claudin 1 Mus musculus 31-36 32626909-14 2020 Amoxicillin decreased KLK4 and CLDN1, CLDN4 and OCLN expression in mature ameloblasts. Amoxicillin 0-11 claudin 4 Mus musculus 38-43 32626909-14 2020 Amoxicillin decreased KLK4 and CLDN1, CLDN4 and OCLN expression in mature ameloblasts. Amoxicillin 0-11 occludin Mus musculus 48-52 32056306-0 2020 CD154 (CD40L): a novel aid to document non-immediate hypersensitivity to amoxicillin or amoxicillin clavulanic acid. Amoxicillin 73-84 CD40 ligand Homo sapiens 0-5 32196862-5 2020 While cefazolin sodium did not exhibit any inhibitory effect, gentamicin and amoxicillin inhibited GR activity in both tissues. Amoxicillin 77-88 glutathione reductase Mus musculus 99-101 32196862-6 2020 Furthermore, the in vivo effects of these drugs were investigated, and amoxicillin and cefazolin sodium-inhibited GR activity in both liver and kidney tissues, while gentamicin did not have any effect on the kidney. Amoxicillin 71-82 glutathione reductase Mus musculus 114-116 32196862-9 2020 This study is important as it demonstrates that while amoxicillin and gentamicin showed parallel effects on the GR activity in liver and kidney tissues both in vitro and in vivo, cefazolin sodium had a very strong effect on hepatic and renal GR in vivo. Amoxicillin 54-65 glutathione reductase Mus musculus 112-114 32196862-0 2020 An in vivo and in vitro comparison of the effects of amoxicillin, gentamicin, and cefazolin sodium antibiotics on the mouse hepatic and renal glutathione reductase enzyme. Amoxicillin 53-64 glutathione reductase Mus musculus 142-163 32196862-2 2020 This is the first study to make a comparison of the impact of frequently prescribed antibiotics, including amoxicillin, gentamicin, and cefazolin sodium, on the gene, protein, and activity of glutathione reductase (GR), which is one of the primary antioxidant enzymes, in mouse liver and kidney tissues. Amoxicillin 107-118 glutathione reductase Mus musculus 192-213 32196862-2 2020 This is the first study to make a comparison of the impact of frequently prescribed antibiotics, including amoxicillin, gentamicin, and cefazolin sodium, on the gene, protein, and activity of glutathione reductase (GR), which is one of the primary antioxidant enzymes, in mouse liver and kidney tissues. Amoxicillin 107-118 glutathione reductase Mus musculus 215-217 32056306-0 2020 CD154 (CD40L): a novel aid to document non-immediate hypersensitivity to amoxicillin or amoxicillin clavulanic acid. Amoxicillin 73-84 CD40 ligand Homo sapiens 7-12 31358361-8 2020 bDMARD naive compared with non-naive ax-SpA patients had better 3-month ASDAS/BASDAI/MHAQ responses (p <= 0.02). Amoxicillin 37-39 surfactant protein A1 Homo sapiens 40-43 32339193-13 2020 This was coupled with the activation of immune-related pathways in explants from amoxicillin-treated pigs (IL-2 production, NO production, BCR activation), when compared to placebo-treated pigs. Amoxicillin 81-92 IL2 Sus scrofa 107-111 32074497-2 2020 At present, proton-pump inhibitor and amoxicillin-based triple therapy, including clarithromycin (PAC) and metronidazole (PAM), are two commonly used first-line therapies for H. pylori infection, which has a high incidence and possibly poor prognosis worldwide. Amoxicillin 38-49 peptidylglycine alpha-amidating monooxygenase Homo sapiens 122-125 31358361-12 2020 Treatment responses were significantly better for bDMARD naive than non-naive ax-SpA patients. Amoxicillin 78-80 surfactant protein A1 Homo sapiens 81-84 31358361-13 2020 Identified predictors of golimumab discontinuation were patient"s global and female gender in patients overall and in subgroups of PsA and ax-SpA patients, and patient"s global and CRP in RA. Amoxicillin 139-141 surfactant protein A1 Homo sapiens 142-145 31482656-0 2020 Host genotype and amoxicillin administration affect the incidence of diarrhoea and faecal microbiota of weaned piglets during a natural multiresistant ETEC infection. Amoxicillin 18-29 ETEC Sus scrofa 151-155 31979034-0 2020 SYN-007, an Orally Administered Beta-Lactamase Enzyme, Protects the Gut Microbiome from Oral Amoxicillin/Clavulanate without Adversely Affecting Antibiotic Systemic Absorption in Dogs. Amoxicillin 93-104 synemin Homo sapiens 0-3 31979034-5 2020 In dogs treated with oral amoxicillin, SYN-007 diminished antibiotic-mediated microbiome disruption and reduced the emergence of antibiotic resistance without altering amoxicillin systemic absorption. Amoxicillin 26-37 synemin Homo sapiens 39-42 33463228-6 2020 The Sr/Fe co-substituted samples demonstrated extended drug (5-fluorouracil and amoxicillin) release profiles at the pH of physiological medium. Amoxicillin 80-91 general transcription factor IIE subunit 1 Homo sapiens 7-9 32238138-10 2020 Statistical analysis revealed a significant association between the iucC gene and resistance to ampicillin (P=0.03) and amoxicillin (P=0.04), and also between fimH and resistance to aztreonam (P=0.03). Amoxicillin 120-131 IucC Escherichia coli 68-72 31613964-1 2020 OBJECTIVES: Escherichia coli is characterized by three resistance patterns to beta-lactams/beta-lactamase inhibitors (BLs/BLIs): (i) resistance to ampicillin/sulbactam and susceptibility to amoxicillin/clavulanic acid and piperacillin/tazobactam (RSS); (ii) resistance to ampicillin/sulbactam and amoxicillin/clavulanic acid, and susceptibility to piperacillin/tazobactam (RRS); and (iii) resistance to ampicillin/sulbactam, amoxicillin/clavulanic acid and piperacillin/tazobactam (RRR). Amoxicillin 190-201 beta-lactamase Escherichia coli 91-105 31482656-3 2020 The interplay between the MUC4 and FUT1 genotypes to ETEC infection and the use of amoxicillin in modifying the intestinal microbiota during a natural infection by multiresistant ETEC strains have never been investigated. Amoxicillin 83-94 ETEC Sus scrofa 179-183 31613964-1 2020 OBJECTIVES: Escherichia coli is characterized by three resistance patterns to beta-lactams/beta-lactamase inhibitors (BLs/BLIs): (i) resistance to ampicillin/sulbactam and susceptibility to amoxicillin/clavulanic acid and piperacillin/tazobactam (RSS); (ii) resistance to ampicillin/sulbactam and amoxicillin/clavulanic acid, and susceptibility to piperacillin/tazobactam (RRS); and (iii) resistance to ampicillin/sulbactam, amoxicillin/clavulanic acid and piperacillin/tazobactam (RRR). Amoxicillin 297-308 beta-lactamase Escherichia coli 91-105 31613964-1 2020 OBJECTIVES: Escherichia coli is characterized by three resistance patterns to beta-lactams/beta-lactamase inhibitors (BLs/BLIs): (i) resistance to ampicillin/sulbactam and susceptibility to amoxicillin/clavulanic acid and piperacillin/tazobactam (RSS); (ii) resistance to ampicillin/sulbactam and amoxicillin/clavulanic acid, and susceptibility to piperacillin/tazobactam (RRS); and (iii) resistance to ampicillin/sulbactam, amoxicillin/clavulanic acid and piperacillin/tazobactam (RRR). Amoxicillin 297-308 beta-lactamase Escherichia coli 91-105 31482656-13 2020 Moreover, our data highlight that group amoxicillin treatment may produce adverse outcomes on pig health in course of multiresistant ETEC infection. Amoxicillin 40-51 ETEC Sus scrofa 133-137 31556759-10 2019 AX-SLN exhibited the protective effect against the LPO, enzymic (SOD, CuZnSOD, MnSOD, GPx, and CAT), and nonenzymic (GSH) in the serum, mammary gland, renal, and hepatic tissues. Amoxicillin 0-2 lactoperoxidase Homo sapiens 51-54 29925282-0 2019 Amoxicillin and gentamicin antibiotics treatment adversely influence the fertility and morphology through decreasing the Dazl gene expression level and increasing the oxidative stress. Amoxicillin 0-11 deleted in azoospermia-like Mus musculus 121-125 31721686-9 2020 In the amoxicillin group, Gr, Gst, Cat, and Sod gene expression levels increased. Amoxicillin 7-18 catalase Mus musculus 35-38 31556759-10 2019 AX-SLN exhibited the protective effect against the LPO, enzymic (SOD, CuZnSOD, MnSOD, GPx, and CAT), and nonenzymic (GSH) in the serum, mammary gland, renal, and hepatic tissues. Amoxicillin 0-2 superoxide dismutase 1 Homo sapiens 65-68 31556759-10 2019 AX-SLN exhibited the protective effect against the LPO, enzymic (SOD, CuZnSOD, MnSOD, GPx, and CAT), and nonenzymic (GSH) in the serum, mammary gland, renal, and hepatic tissues. Amoxicillin 0-2 superoxide dismutase 2 Homo sapiens 79-84 31556759-11 2019 AX-SLN reduced the p-AKT which is accountable for the reduction in the NF-kB expression and also reduced the expression of Keap1 and NF-kB along with increasing the expression of HO-1 and Nrf-2. Amoxicillin 0-2 AKT serine/threonine kinase 1 Homo sapiens 21-24 31556759-11 2019 AX-SLN reduced the p-AKT which is accountable for the reduction in the NF-kB expression and also reduced the expression of Keap1 and NF-kB along with increasing the expression of HO-1 and Nrf-2. Amoxicillin 0-2 kelch like ECH associated protein 1 Homo sapiens 123-128 31556759-11 2019 AX-SLN reduced the p-AKT which is accountable for the reduction in the NF-kB expression and also reduced the expression of Keap1 and NF-kB along with increasing the expression of HO-1 and Nrf-2. Amoxicillin 0-2 heme oxygenase 1 Homo sapiens 179-183 31556759-11 2019 AX-SLN reduced the p-AKT which is accountable for the reduction in the NF-kB expression and also reduced the expression of Keap1 and NF-kB along with increasing the expression of HO-1 and Nrf-2. Amoxicillin 0-2 NFE2 like bZIP transcription factor 2 Homo sapiens 188-193 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 nuclear receptor subfamily 1 group H member 3 Homo sapiens 50-65 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 phosphatase and tensin homolog Homo sapiens 78-82 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 MAF1 homolog, negative regulator of RNA polymerase III Homo sapiens 84-88 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 mechanistic target of rapamycin kinase Homo sapiens 96-100 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 AKT serine/threonine kinase 1 Homo sapiens 102-105 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 fatty acid synthase Homo sapiens 107-111 31556759-12 2019 Further, AX-SLN significantly altered the mRNA of LXR (alpha,beta), HMG-CoAR, PTEN, Maf1, PI3K, mTOR, Akt, FASN, and ACC1. Amoxicillin 9-11 BCL2 related protein A1 Homo sapiens 117-121 31556759-13 2019 On the basis of the results, we can conclude that AX-SLN inhibits the mammary gland carcinogenesis via Nrf-2-Keap1, NF-kB, and mTOR/Maf-1/PTEN pathway. Amoxicillin 50-52 NFE2 like bZIP transcription factor 2 Homo sapiens 103-108 31556759-13 2019 On the basis of the results, we can conclude that AX-SLN inhibits the mammary gland carcinogenesis via Nrf-2-Keap1, NF-kB, and mTOR/Maf-1/PTEN pathway. Amoxicillin 50-52 kelch like ECH associated protein 1 Homo sapiens 109-114 31556759-13 2019 On the basis of the results, we can conclude that AX-SLN inhibits the mammary gland carcinogenesis via Nrf-2-Keap1, NF-kB, and mTOR/Maf-1/PTEN pathway. Amoxicillin 50-52 mechanistic target of rapamycin kinase Homo sapiens 127-131 31556759-13 2019 On the basis of the results, we can conclude that AX-SLN inhibits the mammary gland carcinogenesis via Nrf-2-Keap1, NF-kB, and mTOR/Maf-1/PTEN pathway. Amoxicillin 50-52 MAF1 homolog, negative regulator of RNA polymerase III Homo sapiens 132-137 31556759-13 2019 On the basis of the results, we can conclude that AX-SLN inhibits the mammary gland carcinogenesis via Nrf-2-Keap1, NF-kB, and mTOR/Maf-1/PTEN pathway. Amoxicillin 50-52 phosphatase and tensin homolog Homo sapiens 138-142 31875435-15 2019 The adjunctive benefits of systemic metronidazole and amoxicillin in non-surgical periodontal therapy are decreased serum IL-6 expression and normal carotid artery. Amoxicillin 54-65 interleukin 6 Rattus norvegicus 122-126 31106471-5 2019 Therefore, we here evaluated the effects of amoxicillin and various SCFA on hepatic ApoA-I expression, secretion, and the putative underlying pathways. Amoxicillin 44-55 apolipoprotein A1 Homo sapiens 84-90 31783518-0 2019 Amoxicillin Modulates ApoA-I Transcription and Secretion, Predominantly via PPARalpha Transactivation Inhibition. Amoxicillin 0-11 apolipoprotein A1 Homo sapiens 22-28 31783518-0 2019 Amoxicillin Modulates ApoA-I Transcription and Secretion, Predominantly via PPARalpha Transactivation Inhibition. Amoxicillin 0-11 peroxisome proliferator activated receptor alpha Homo sapiens 76-85 31783518-6 2019 In HepG2 and Caco-2, amoxicillin decreased ApoA-I transcription and secretion. Amoxicillin 21-32 apolipoprotein A1 Homo sapiens 43-49 31783518-7 2019 Effects on ApoA-I expression were clearly there for amoxicillin while no effects were observed for penicillin or streptomycin. Amoxicillin 52-63 apolipoprotein A1 Homo sapiens 11-17 31783518-8 2019 KEAP1, CPT1, and CHOP mRNA expressions were reduced by amoxicillin treatments. Amoxicillin 55-66 kelch like ECH associated protein 1 Homo sapiens 0-5 31783518-8 2019 KEAP1, CPT1, and CHOP mRNA expressions were reduced by amoxicillin treatments. Amoxicillin 55-66 carnitine palmitoyltransferase 1A Homo sapiens 7-11 31783518-8 2019 KEAP1, CPT1, and CHOP mRNA expressions were reduced by amoxicillin treatments. Amoxicillin 55-66 DNA damage inducible transcript 3 Homo sapiens 17-21 31783518-10 2019 Furthermore, amoxicillin lowered PPARalpha transactivation. Amoxicillin 13-24 peroxisome proliferator activated receptor alpha Homo sapiens 33-42 31783518-11 2019 All together, these data suggest that inhibited PPARalpha transactivation is involved in the effects of amoxicillin on ApoA-I. Amoxicillin 104-115 peroxisome proliferator activated receptor alpha Homo sapiens 48-57 31783518-11 2019 All together, these data suggest that inhibited PPARalpha transactivation is involved in the effects of amoxicillin on ApoA-I. Amoxicillin 104-115 apolipoprotein A1 Homo sapiens 119-125 31783518-12 2019 In conclusion, the direct effect of amoxicillin in treated HepG2 and Caco-2 cells was a lower ApoA-I secretion and transcription. Amoxicillin 36-47 apolipoprotein A1 Homo sapiens 94-100 31783518-13 2019 Based on evaluating alterations in KEAP1, CPT1, and CHOP mRNA expressions plus PPARalpha transactivation, we suggest that a reduced PPARalpha activation is a potential mechanism behind the observed amoxicillin effects on ApoA-I expression. Amoxicillin 198-209 kelch like ECH associated protein 1 Homo sapiens 35-40 31783518-13 2019 Based on evaluating alterations in KEAP1, CPT1, and CHOP mRNA expressions plus PPARalpha transactivation, we suggest that a reduced PPARalpha activation is a potential mechanism behind the observed amoxicillin effects on ApoA-I expression. Amoxicillin 198-209 carnitine palmitoyltransferase 1A Homo sapiens 42-46 31783518-13 2019 Based on evaluating alterations in KEAP1, CPT1, and CHOP mRNA expressions plus PPARalpha transactivation, we suggest that a reduced PPARalpha activation is a potential mechanism behind the observed amoxicillin effects on ApoA-I expression. Amoxicillin 198-209 DNA damage inducible transcript 3 Homo sapiens 52-56 31783518-13 2019 Based on evaluating alterations in KEAP1, CPT1, and CHOP mRNA expressions plus PPARalpha transactivation, we suggest that a reduced PPARalpha activation is a potential mechanism behind the observed amoxicillin effects on ApoA-I expression. Amoxicillin 198-209 peroxisome proliferator activated receptor alpha Homo sapiens 79-88 31783518-13 2019 Based on evaluating alterations in KEAP1, CPT1, and CHOP mRNA expressions plus PPARalpha transactivation, we suggest that a reduced PPARalpha activation is a potential mechanism behind the observed amoxicillin effects on ApoA-I expression. Amoxicillin 198-209 peroxisome proliferator activated receptor alpha Homo sapiens 132-141 31783518-13 2019 Based on evaluating alterations in KEAP1, CPT1, and CHOP mRNA expressions plus PPARalpha transactivation, we suggest that a reduced PPARalpha activation is a potential mechanism behind the observed amoxicillin effects on ApoA-I expression. Amoxicillin 198-209 apolipoprotein A1 Homo sapiens 221-227 30104087-8 2019 RESULTS: Strains isolated from patients with uncomplicated UTI showed significantly greater susceptibility than those of complicated UTI to amoxicillin (65.9% vs. 30.6%, p=0.001), amoxicillin/clavulanic acid (95.5% vs. 77.6%, p=0.013) and ciprofloxacin (81.8% vs. 63.3%, p=0.047). Amoxicillin 140-151 alpha-1-microglobulin/bikunin precursor Homo sapiens 133-136 31684989-13 2019 Children with diarrhoea AHR = 0.81 with 95% CI (0.73, 0.99), children taken amoxicillin AHR = 2.304 with 95% CI (1.68-3.161), and had vomiting at admission AHR = 0.430 with 95% CI (0.205, 0.904) were significant predictors of time to recovery. Amoxicillin 76-87 aryl hydrocarbon receptor Homo sapiens 88-91 31684989-13 2019 Children with diarrhoea AHR = 0.81 with 95% CI (0.73, 0.99), children taken amoxicillin AHR = 2.304 with 95% CI (1.68-3.161), and had vomiting at admission AHR = 0.430 with 95% CI (0.205, 0.904) were significant predictors of time to recovery. Amoxicillin 76-87 aryl hydrocarbon receptor Homo sapiens 88-91 31070244-12 2019 An amoxicillin-modified 9-mer peptide derived from the exosomal transcription factor protein SRY (sex determining region Y)-box 30 activated naive T cells from human leukocyte antigen A*02:01-positive human donors. Amoxicillin 3-14 sex determining region Y Homo sapiens 93-96 31106471-9 2019 Amoxicillin dose-dependently decreased ApoA-I mRNA transcription as well as ApoA-I protein secretion. Amoxicillin 0-11 apolipoprotein A1 Homo sapiens 39-45 31106471-9 2019 Amoxicillin dose-dependently decreased ApoA-I mRNA transcription as well as ApoA-I protein secretion. Amoxicillin 0-11 apolipoprotein A1 Homo sapiens 76-82 31106471-12 2019 CONCLUSION: Direct treatment of HepG2 cells with amoxicillin has either direct effects on lowering ApoA-I transcription and secretion or indirect effects via modified SCFA concentrations because SCFA were found to stimulate hepatic ApoA-I expression. Amoxicillin 49-60 apolipoprotein A1 Homo sapiens 99-105 31106471-12 2019 CONCLUSION: Direct treatment of HepG2 cells with amoxicillin has either direct effects on lowering ApoA-I transcription and secretion or indirect effects via modified SCFA concentrations because SCFA were found to stimulate hepatic ApoA-I expression. Amoxicillin 49-60 apolipoprotein A1 Homo sapiens 232-238 30976089-9 2019 Amoxicillin reduced bacterial populations in the lungs and reduced NLRP3 inflammasome protein levels, but did not reduce PAFR. Amoxicillin 0-11 NLR family pyrin domain containing 3 Homo sapiens 67-72 30989200-5 2019 RESULTS: We showed that drugs that are commonly used to treat Gram-negative bacterial infections, such as ampicillin and amoxicillin, could enrich both carbapenem-resistant Enterobacteriaceae (CRE) and antibiotic-susceptible E. coli in the GI tract, thereby promoting transmission of the blaNDM-1-bearing plasmid in the gut microbiome. Amoxicillin 121-132 NDM-1 metallo-beta-lactamase Escherichia coli 288-296 30925667-4 2019 The secondary structure of bovine serum albumin (BSA) was altered by the binding of drugs, like amoxicillin (Amox), cephalexin (Cefa), and azithromycin (Azit). Amoxicillin 96-107 albumin Homo sapiens 34-47 31226961-5 2019 Amoxicillin was administered at a dose of 40-50 mg/kg/day, divided into one (QD), two (BID), or three (TID) daily doses, for 10 days. Amoxicillin 0-11 BH3 interacting domain death agonist Homo sapiens 87-90 30664875-8 2019 Among amoxicillin- and clavulanate-associated cases of European ancestry, rs2476601 doubled the risk for DILI among those with the HLA risk alleles A*02:01 and DRB1*15:01. Amoxicillin 6-17 major histocompatibility complex, class II, DR beta 1 Homo sapiens 160-164 31249354-11 2019 The optimal conditions for the photocatalytic degradation of AMO are found to be an initial AMO concentration of 1.0 muM, a catalyst dosage of 0.104 g/L, and a pH of 4, under which almost complete removal of AMO is achieved (99.99%). Amoxicillin 61-64 latexin Homo sapiens 117-120 31249354-11 2019 The optimal conditions for the photocatalytic degradation of AMO are found to be an initial AMO concentration of 1.0 muM, a catalyst dosage of 0.104 g/L, and a pH of 4, under which almost complete removal of AMO is achieved (99.99%). Amoxicillin 92-95 latexin Homo sapiens 117-120 31100958-5 2019 AMX/AMC was given for 14 days and rationalized according to microbiological pleural tap results. Amoxicillin 0-3 nuclear RNA export factor 1 Homo sapiens 84-87 31100958-12 2019 In conclusion, 14-day AMX/AMC treatment confirmed and rarely modified by microbiological findings from pleural tap resulted in full recovery in >95% of children with PPE/PE. Amoxicillin 22-25 nuclear RNA export factor 1 Homo sapiens 111-114 30673828-9 2019 The disappearance of Ax+ was associated with high pre-NAC CTLA-4 levels (p = 0.0278) and elevated CD4 levels after NAC (p = 0.0250). Amoxicillin 21-24 cytotoxic T-lymphocyte associated protein 4 Homo sapiens 58-64 30673828-9 2019 The disappearance of Ax+ was associated with high pre-NAC CTLA-4 levels (p = 0.0278) and elevated CD4 levels after NAC (p = 0.0250). Amoxicillin 21-24 CD4 molecule Homo sapiens 98-101 30668729-1 2019 OBJECTIVES: To evaluate the in vitro antimicrobial/antivirulence action of bovine lactoferrin and its ability to synergize with levofloxacin against resistant Helicobacter pylori strains and to analyse the effect of levofloxacin, amoxicillin and esomeprazole with and without bovine lactoferrin as the first-line treatment for H. pylori infection. Amoxicillin 230-241 lactotransferrin Bos taurus 82-93 30925667-4 2019 The secondary structure of bovine serum albumin (BSA) was altered by the binding of drugs, like amoxicillin (Amox), cephalexin (Cefa), and azithromycin (Azit). Amoxicillin 109-113 albumin Homo sapiens 34-47 30562656-4 2019 The prepared MOF nanosheets and nanoflowers (with particle size average of 95 and 116 nm, respectively) were employed to adsorb the ampicillin, amoxicillin and cloxacillin antibiotics. Amoxicillin 144-155 lysine acetyltransferase 8 Homo sapiens 13-16 30123199-6 2018 All ESBL producers exhibited multidrug resistance (MDR) phenotype, and more than 90% of the ESBL producers were resistant to amoxicillin, amoxicillin-clavulanic acid, oxytetracycline, enrofloxacin and sulfamethoxazole/trimethoprim. Amoxicillin 125-136 EsbL Escherichia coli 92-96 30556617-8 2019 RESULTS: Clinical review revealed a similar statistical pattern of gender difference observed for amoxicillin, evidence to suggest a delayed type 4 hypersensitivity reaction with Th1 cells as a mechanism for amoxicillin-aseptic meningitis, the existence of sex differences in immune responses (Th1/Th2), and an analogous increased risk of drug-induced liver injury by AC in males. Amoxicillin 98-109 negative elongation factor complex member C/D Homo sapiens 179-182 30556617-8 2019 RESULTS: Clinical review revealed a similar statistical pattern of gender difference observed for amoxicillin, evidence to suggest a delayed type 4 hypersensitivity reaction with Th1 cells as a mechanism for amoxicillin-aseptic meningitis, the existence of sex differences in immune responses (Th1/Th2), and an analogous increased risk of drug-induced liver injury by AC in males. Amoxicillin 208-219 negative elongation factor complex member C/D Homo sapiens 179-182 30031112-6 2018 7 days of pre-treatment with amoxicillin or single dose of fosfomycin decreased the AQP5 protein level, while 7 days of treatment with doxycycline had no effect. Amoxicillin 29-40 aquaporin 5 Rattus norvegicus 84-88 30031112-8 2018 Amoxicillin and fosfomycin may sensitize the uterus to oxytocin via the reduction of AQP5 expression. Amoxicillin 0-11 aquaporin 5 Rattus norvegicus 85-89 30034150-10 2018 Conclusion: Amoxicillin possess antimicrobial activity against major pathogens in orofacial odontogenic infections, but beta-lactamase production has restricted the effectiveness of amoxicillin against the resistant strains of Staphylococcus aureus, Bacteroides, Prevotella and Porphyromonas. Amoxicillin 182-193 beta-lactamase Staphylococcus aureus 120-134 30236958-1 2019 This study aimed to evaluate the potential synergistic and bactericidal effects of mecillinam in combination with amoxicillin and clavulanic acid against extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli. Amoxicillin 114-125 EsbL Escherichia coli 154-186 30465653-4 2018 METHODS: In a post hoc analysis of patients with moderate-severe CAP in seven Dutch hospitals, we compared in vitro antibiotic susceptibilities of definite and possible causative pathogens of CAP and HCAP to amoxicillin and broader antibiotic regimens. Amoxicillin 208-219 structural maintenance of chromosomes 3 Homo sapiens 200-204 30465653-8 2018 The largest reduction in non-susceptibility was achieved by adding ciprofloxacin to amoxicillin treatment in both CAP patients (10% absolute risk reduction) and HCAP patients (11-16% reduction). Amoxicillin 84-95 structural maintenance of chromosomes 3 Homo sapiens 161-165 30465653-9 2018 CONCLUSIONS: In the Netherlands, HCAP criteria predict higher amoxicillin non-susceptibility in patients hospitalized with moderate-severe CAP. Amoxicillin 62-73 structural maintenance of chromosomes 3 Homo sapiens 33-37 30012768-5 2018 Similarly, the Km of prothionamide was 805.8 +- 23.4 muM for OCT1, while the Km values of isoniazid and amoxicillin for organic anion transporter 3 (OAT3) were 233.7 +- 14.1 and 161.4 +- 10.6 muM, respectively. Amoxicillin 104-115 solute carrier family 22 member 8 Homo sapiens 120-147 30012768-5 2018 Similarly, the Km of prothionamide was 805.8 +- 23.4 muM for OCT1, while the Km values of isoniazid and amoxicillin for organic anion transporter 3 (OAT3) were 233.7 +- 14.1 and 161.4 +- 10.6 muM, respectively. Amoxicillin 104-115 solute carrier family 22 member 8 Homo sapiens 149-153 30012768-5 2018 Similarly, the Km of prothionamide was 805.8 +- 23.4 muM for OCT1, while the Km values of isoniazid and amoxicillin for organic anion transporter 3 (OAT3) were 233.7 +- 14.1 and 161.4 +- 10.6 muM, respectively. Amoxicillin 104-115 latexin Homo sapiens 192-195 29953881-5 2018 The aim of our study was the elucidation of the structural aspects of the inhibitory mechanism of ampicillin, gentamicin, amoxicillin, prednisolone and norepinephrine on LPO. Amoxicillin 122-133 lactoperoxidase Homo sapiens 170-173 29515175-10 2018 Groups treated with amoxicillin, amoxicillin/clavulanate, erythromycin and acetaminophen showed significantly lower amounts of immunoreactive COX2 at the enamel organ maturation stage of the mouse incisors. Amoxicillin 20-31 prostaglandin-endoperoxide synthase 2 Mus musculus 142-146 28087317-11 2018 Serotype 19A ST320 caused 90% of AOM episodes in children aged <= 12 months and had had higher resistance rates to penicillin according to meningeal breakpoints (p = 0.011), amoxicillin (p < 0.001) and trimethoprim/sulfamethoxazol (p < 0.001). Amoxicillin 177-188 SLAM family member 7 Homo sapiens 9-12 28597369-0 2018 First report of real-time monitoring of coagulation function potential and IgG subtype of anti-FVIII autoantibodies in a child with acquired hemophilia A associated with streptococcal infection and amoxicillin. Amoxicillin 198-209 coagulation factor VIII Homo sapiens 95-100 29805399-3 2018 Specimens were randomly divided into four experimental groups and treated with an intracanal medicament [calcium hydroxide (CH), double antibiotic paste (DAP), triple antibiotic paste (TAP), TAP with amoxicillin (mTAP)] and a non-treated control group. Amoxicillin 200-211 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Mus musculus 191-194 30100654-11 2018 A significant association was found between ESBL-producing uropathogens against ciprofloxacin, enoxacin, and amoxicillin/clavulanic acid resistance (P < 0.05). Amoxicillin 109-120 EsbL Escherichia coli 44-48 29226807-0 2018 Asthma, Family History of Drug Allergy, and Age Predict Amoxicillin Allergy in Children. Amoxicillin 56-67 renin binding protein Homo sapiens 44-47 29665345-0 2018 Evaluation of IFN-gamma Enzyme-linked Immunospot Assay (ELISPOT) as a First-line Test in the Diagnosis of Non-Immediate Hypersensitivity to Amoxicillin and Penicillin. Amoxicillin 140-151 interferon gamma Homo sapiens 14-23 29226807-11 2018 The presence of asthma, family history of drug allergy, and older age at reaction can be used as predictive factors for true amoxicillin allergy in children. Amoxicillin 125-136 renin binding protein Homo sapiens 66-69 29665345-3 2018 We aimed to verify the utility of IFN-gamma ELISPOT as a first-line test in patients with suspected non-immediate hypersensitivity reaction to amoxicillin (AMX) and penicillin (PNC). Amoxicillin 143-154 interferon gamma Homo sapiens 34-43 29665345-3 2018 We aimed to verify the utility of IFN-gamma ELISPOT as a first-line test in patients with suspected non-immediate hypersensitivity reaction to amoxicillin (AMX) and penicillin (PNC). Amoxicillin 156-159 interferon gamma Homo sapiens 34-43 28204842-11 2017 Within the limits of the study, it can be stated that nonsurgical periodontal therapy with additional systemic administration of Amoxicillin and Metronidazole increases the level of HNP1-3 in GCF. Amoxicillin 129-140 HNP1 Homo sapiens 182-186 28486532-18 2017 In conclusion, nitrofurantoin and amoxicillin should be used as first line antibiotic treatment for uncomplicated UTI. Amoxicillin 34-45 alpha-1-microglobulin/bikunin precursor Homo sapiens 114-117 28444390-6 2017 High-mobility group box 1 protein (HMGB1) and lactate dehydrogenase release as well as adenosine triphosphate depletion occurred in a drug-, time-, and concentration-dependent manner with SMX-NO and flucloxacillin, whereas isoniazid and amoxicillin were nontoxic. Amoxicillin 237-248 high mobility group box 1 Homo sapiens 0-25 28444390-6 2017 High-mobility group box 1 protein (HMGB1) and lactate dehydrogenase release as well as adenosine triphosphate depletion occurred in a drug-, time-, and concentration-dependent manner with SMX-NO and flucloxacillin, whereas isoniazid and amoxicillin were nontoxic. Amoxicillin 237-248 high mobility group box 1 Homo sapiens 35-40 28952295-8 2017 The improvement of white blood cells and CRP levels of the amoxicillin and clavulanate potassium group was more obvious than that of the ceftezole sodium group (P<0.05). Amoxicillin 59-70 C-reactive protein Homo sapiens 41-44 28577017-3 2017 The present study aimed to assess the effects of CYP2C19 gene polymorphisms on proton pump inhibitor (PPI), amoxicillin, and levofloxacin triple therapy for Helicobacter pylori (Hp) eradication. Amoxicillin 108-119 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 49-56 28216332-0 2017 Erratum to "Virtual mutation and directional evolution of anti-amoxicillin ScFv antibody for immunoassay of penicillins in milk" [Anal. Amoxicillin 63-74 immunglobulin heavy chain variable region Homo sapiens 75-79 28069651-6 2017 The hydrolysis of amoxicillin and nitrocefin by KPC-2 and CTX-M-15 was moderately affected by the substitution N132G, but that of ceftazidime, ceftaroline, and aztreonam was drastically reduced. Amoxicillin 18-29 UBA domain containing 1 Homo sapiens 48-53 28368864-5 2017 All ESBL producers were resistant to ampicillin, cephalexin, cefalotin, cefpodoxime, ceftiofur, enrofloxacin, marbofloxacin, and trimethoprim/sulfamethoxazole, but were susceptible to imipenem and amoxicillin/clavulanic acid. Amoxicillin 197-208 EsbL Escherichia coli 4-8 27780696-0 2017 Virtual mutation and directional evolution of anti-amoxicillin ScFv antibody for immunoassay of penicillins in milk. Amoxicillin 51-62 immunglobulin heavy chain variable region Homo sapiens 63-67 27420342-4 2016 This study was concerned with testing the potential removal of Amoxicillin in different solutions (tap water, well water, river water, and the weakly saline water). Amoxicillin 63-74 nuclear RNA export factor 1 Homo sapiens 99-102 27780696-1 2017 In this study, an anti-amoxicillin single chain variable fragment (ScFv) antibody was evolved by directional mutagenesis of a contact amino acid residue based on the analysis of virtual mutation. Amoxicillin 23-34 immunglobulin heavy chain variable region Homo sapiens 67-71 28752505-2 2017 Compared to clindamycin the concentration of amoxicillin in teeth and bone (Hallig 2014) is higher and has less gastrointestinal side-effects (Bax 2007). Amoxicillin 45-56 BCL2 associated X, apoptosis regulator Homo sapiens 143-146 27402969-8 2016 RESULTS: Amoxicillin was associated with an ICER of $8216 ($6540) per QALY gained when the cost of resistance was excluded. Amoxicillin 9-20 cAMP responsive element modulator Homo sapiens 44-48 27383141-0 2016 Production of anti-amoxicillin ScFv antibody and simulation studying its molecular recognition mechanism for penicillins. Amoxicillin 19-30 immunglobulin heavy chain variable region Homo sapiens 31-35 27383141-3 2016 The single chain variable fragment (ScFv) antibody was generated from a hybridoma cell strain excreting the monoclonal antibody for amoxicillin. Amoxicillin 132-143 immunglobulin heavy chain variable region Homo sapiens 36-40 26976869-2 2016 Rifabutin, ethambutol, amoxicillin, linezolid, p-amino salicylic acid, and rifapentine exhibited mild to moderate inhibitory effects on OATP-mediated uptake of estrone-3 sulfate, estradiol 17beta-d-glucuronide, and rosuvastatin. Amoxicillin 23-34 solute carrier organic anion transporter family member 1A2 L homeolog Xenopus laevis 136-140 27199635-3 2016 Importantly, we recently reported that amoxicillin and Augmentin (amoxicillin/clavulanate) upreglulated GLT-1 expression in nucleus accumbens (NAc) and prefrontal cortex (PFC) as well as reduced ethanol consumption in male P rats. Amoxicillin 39-50 solute carrier family 1 member 2 Rattus norvegicus 104-109 26763401-4 2016 However, amoxicillin and piperacillin inhibited CYP2C8-mediated aminopyrine N-demethylation at 50% inhibitory concentration of 0.83 and 1.14 mM, respectively. Amoxicillin 9-20 cytochrome P450 family 2 subfamily C member 8 Homo sapiens 48-54 27199635-4 2016 In this study, we examined the effects of amoxicillin and Augmentin on GLT-1 isoforms (GLT-1a and GLT-1b), xCT, and glutamate/aspartate transporter (GLAST) expression in NAc and PFC as well as ethanol intake in male P rats. Amoxicillin 42-53 solute carrier family 1 member 2 Rattus norvegicus 71-76 27199635-8 2016 These findings demonstrated that Augmentin and amoxicillin have the potential to upregulate GLT-1 isoforms and xCT expression, and consequently attenuate ethanol dependence. Amoxicillin 47-58 solute carrier family 1 member 2 Rattus norvegicus 92-97 26928597-9 2016 CONCLUSION: Adjunctive systemic amoxicillin and metronidazole medication to SRP significantly improved the clinical outcomes with respect to mean PD, CAL and BOP compared to SRP alone. Amoxicillin 32-43 BOP Homo sapiens 158-161 26763401-1 2016 The effects of three kinds of penicillin-based antibiotics, amoxicillin, ampicillin, and piperacillin, on drug-metabolizing activity of human hepatic cytochrome P450 (P450 or CYP) were investigated. Amoxicillin 60-71 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 167-178 26805829-0 2016 Construction of an Electrochemical Sensor Based on Carbon Nanotubes/Gold Nanoparticles for Trace Determination of Amoxicillin in Bovine Milk. Amoxicillin 114-125 Weaning weight-maternal milk Bos taurus 136-140 26416900-6 2016 Penicillin and amoxicillin were the antibiotics most commonly recommended for respiratory tract infections (RTIs) (up to 76%), cephalosporin for UTI (up to 50%) and for skin and soft tissue infection (SSTI) and bone infection (20% and 30%, respectively). Amoxicillin 15-26 alpha-1-microglobulin/bikunin precursor Homo sapiens 145-148 26805829-1 2016 In this work, a novel electrochemical sensor was fabricated for determination of amoxicillin in bovine milk samples by decoration of carboxylated multi-walled carbon nanotubes (MWCNTs) with gold nanoparticles (AuNPs) using ethylenediamine (en) as a cross linker (AuNPs/en-MWCNTs). Amoxicillin 81-92 Weaning weight-maternal milk Bos taurus 103-107 26805829-8 2016 The fabricated electrochemical sensor was successfully applied for determination of Amoxicillin in bovine milk samples and all results compared with high performance liquid chromatography (HPLC) standard method. Amoxicillin 84-95 Weaning weight-maternal milk Bos taurus 106-110 26349821-7 2015 In addition, plasma cystatin C and concomitant treatment with vasopressors were identified to have a significant influence on amoxicillin clearance. Amoxicillin 126-137 cystatin C Homo sapiens 20-30 26613181-10 2016 Nevertheless the abiotic degradation of TP 1, TP 2 and TP 3 to further TPs needs to be considered in future studies of the environmental fate of amoxicillin. Amoxicillin 145-156 transition protein 1 Homo sapiens 40-44 26518125-11 2015 iha and afa/draBC genes were more frequent in resistant isolates than the susceptible ones; for iha, in ampicillin, amoxicillin/clavulanic acid, nalidixic acid, cefuroxime, ceftriaxone resistant and ESBL and MDR positive isolates; for afa/draBC, in cefotaxime, cefuroxime, ciprofloxacin, trimethoprim/sulfamethoxazole resistant and ESBL and MDR positive isolates, this trend was observed. Amoxicillin 116-127 AFA Homo sapiens 8-11 26518125-11 2015 iha and afa/draBC genes were more frequent in resistant isolates than the susceptible ones; for iha, in ampicillin, amoxicillin/clavulanic acid, nalidixic acid, cefuroxime, ceftriaxone resistant and ESBL and MDR positive isolates; for afa/draBC, in cefotaxime, cefuroxime, ciprofloxacin, trimethoprim/sulfamethoxazole resistant and ESBL and MDR positive isolates, this trend was observed. Amoxicillin 116-127 AFA Homo sapiens 235-238 26168897-0 2015 Amoxicillin and amoxicillin/clavulanate reduce ethanol intake and increase GLT-1 expression as well as AKT phosphorylation in mesocorticolimbic regions. Amoxicillin 0-11 solute carrier family 1 member 2 Homo sapiens 75-80 25713485-0 2015 Impact of metronidazole and amoxicillin combination on matrix metalloproteinases-1 and tissue inhibitors of matrix metalloproteinases balance in generalized aggressive periodontitis. Amoxicillin 28-39 matrix metallopeptidase 1 Homo sapiens 55-82 26066898-11 2015 DXM/amoxicillin treated mice, compared to the two other groups, also showed lower levels of TNF-alpha and lower bacterial blood load assessed by serial dilutions of blood and bioluminescence dynamic imaging. Amoxicillin 4-15 tumor necrosis factor Mus musculus 92-101 25583725-5 2015 Exposure of the M. catarrhalis strains O35E and 300 to amoxicillin triggered an increased transcription of all AcrAB-OprM pump genes, and exposure of strains O35E, 300, and 415 to clarithromycin enhanced the expression of acrA and oprM mRNA. Amoxicillin 55-66 opioid receptor mu 1 Homo sapiens 117-121 25583725-5 2015 Exposure of the M. catarrhalis strains O35E and 300 to amoxicillin triggered an increased transcription of all AcrAB-OprM pump genes, and exposure of strains O35E, 300, and 415 to clarithromycin enhanced the expression of acrA and oprM mRNA. Amoxicillin 55-66 opioid receptor mu 1 Homo sapiens 231-235 25998949-3 2015 Lymphocytes from 6 of 7 patients were found to proliferate and/or secrete interferon-gamma (IFN-gamma) when cultured with amoxicillin and/or clavulanic acid. Amoxicillin 122-133 interferon gamma Homo sapiens 74-90 25998949-3 2015 Lymphocytes from 6 of 7 patients were found to proliferate and/or secrete interferon-gamma (IFN-gamma) when cultured with amoxicillin and/or clavulanic acid. Amoxicillin 122-133 interferon gamma Homo sapiens 92-101 25998949-4 2015 Amoxicillin (n = 105) and clavulanic acid (n = 16) responsive CD4(+) and CD8(+) T-cell clones expressing CCR, chemokine (C-C motif) receptor 4, CCR9, and chemokine (C-X-C motif) receptor 3 were generated from patients with and without HLA risk alleles; no cross-reactivity was observed between the two drug antigens. Amoxicillin 0-11 CD4 molecule Homo sapiens 62-65 25998949-4 2015 Amoxicillin (n = 105) and clavulanic acid (n = 16) responsive CD4(+) and CD8(+) T-cell clones expressing CCR, chemokine (C-C motif) receptor 4, CCR9, and chemokine (C-X-C motif) receptor 3 were generated from patients with and without HLA risk alleles; no cross-reactivity was observed between the two drug antigens. Amoxicillin 0-11 C-C motif chemokine receptor 4 Homo sapiens 110-142 25998949-5 2015 Amoxicillin clones were found to secrete a heterogeneous panel of mediators, including IFN-gamma, interleukin-22 and cytolytic molecules. Amoxicillin 0-11 interferon gamma Homo sapiens 87-96 25998949-5 2015 Amoxicillin clones were found to secrete a heterogeneous panel of mediators, including IFN-gamma, interleukin-22 and cytolytic molecules. Amoxicillin 0-11 interleukin 22 Homo sapiens 98-112 28717471-10 2015 Moreover, GlcEnt-Amp/Amx evade the host-defense protein lipocalin-2, and exhibit low toxicity to mammalian cells. Amoxicillin 21-24 lipocalin 2 Homo sapiens 56-67 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 144-155 suppressor of cytokine signaling 1 Mus musculus 59-64 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 144-155 suppressor of cytokine signaling 3 Mus musculus 66-71 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 144-155 tumor necrosis factor Mus musculus 73-82 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 144-155 interferon gamma Mus musculus 88-97 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 175-186 suppressor of cytokine signaling 1 Mus musculus 59-64 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 175-186 suppressor of cytokine signaling 3 Mus musculus 66-71 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 175-186 tumor necrosis factor Mus musculus 73-82 26261565-7 2015 Compared to the model group, the mRNA expression levels of SOCS1, SOCS3, TNF-alpha, and IFN-gamma were significantly decreased in OM-85-BV plus amoxicillin group and isolated amoxicillin group, along with the protein levels. Amoxicillin 175-186 interferon gamma Mus musculus 88-97 26007680-0 2015 Effect of nonsurgical periodontal treatment in conjunction with either systemic administration of amoxicillin and metronidazole or additional photodynamic therapy on the concentration of matrix metalloproteinases 8 and 9 in gingival crevicular fluid in patients with aggressive periodontitis. Amoxicillin 98-109 matrix metallopeptidase 8 Homo sapiens 187-220 25615803-5 2015 For promazine and amoxicillin, they resulted in the change of binding force distribution of myoglobin/antibody (i.e., from unimodal distribution to bimodal distribution) and the increase of binding probability; for aspirin, it only resulted in the change of the binding force distribution, and for sodium penicillin, it resulted in the increase of the average binding force and the binding probability. Amoxicillin 18-29 myoglobin Homo sapiens 92-101 25713485-2 2015 We hypothesized that better clinical healing of adjunctive use of amoxicillin plus metronidazole combination may be related to the effect of this combination therapy to restore imbalance between matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) which is associated with connective tissue and alveolar bone destruction in patients with GAgP. Amoxicillin 66-77 matrix metallopeptidase 1 Homo sapiens 222-225 25713485-2 2015 We hypothesized that better clinical healing of adjunctive use of amoxicillin plus metronidazole combination may be related to the effect of this combination therapy to restore imbalance between matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP) which is associated with connective tissue and alveolar bone destruction in patients with GAgP. Amoxicillin 66-77 TIMP metallopeptidase inhibitor 1 Homo sapiens 256-260 25713485-13 2015 CONCLUSION: The results of this study suggest that metronidazole and amoxicillin combination as an adjunct to SRP results in better clinical healing through restoring TIMP-1/MMP-1 balance. Amoxicillin 69-80 TIMP metallopeptidase inhibitor 1 Homo sapiens 167-173 25713485-13 2015 CONCLUSION: The results of this study suggest that metronidazole and amoxicillin combination as an adjunct to SRP results in better clinical healing through restoring TIMP-1/MMP-1 balance. Amoxicillin 69-80 matrix metallopeptidase 1 Homo sapiens 174-179 25224099-7 2015 Single nucleotide polymorphisms of HLA-DRA and ZNF300 predicted skin test positivity to amoxicillin and other penicillins but not to cephalosporins. Amoxicillin 88-99 major histocompatibility complex, class II, DR alpha Homo sapiens 35-42 25968421-0 2015 Anti-Amoxicillin Immunoglobulin E, Histamine-2 Receptor Antagonist Therapy and Mast Cell Activation Syndrome Are Risk Factors for Amoxicillin Anaphylaxis. Amoxicillin 5-16 immunoglobulin heavy constant epsilon Homo sapiens 17-33 25968421-0 2015 Anti-Amoxicillin Immunoglobulin E, Histamine-2 Receptor Antagonist Therapy and Mast Cell Activation Syndrome Are Risk Factors for Amoxicillin Anaphylaxis. Amoxicillin 130-141 immunoglobulin heavy constant epsilon Homo sapiens 17-33 25224099-7 2015 Single nucleotide polymorphisms of HLA-DRA and ZNF300 predicted skin test positivity to amoxicillin and other penicillins but not to cephalosporins. Amoxicillin 88-99 zinc finger protein 300 Homo sapiens 47-53 25224099-9 2015 HLA-DRA rs7192 and rs8084 were significantly associated with allergy to penicillins and amoxicillin (P = 6.0 x 10(-4) and P = 4.0 x 10(-4), respectively) but not to cephalosporins in the replication study. Amoxicillin 88-99 major histocompatibility complex, class II, DR alpha Homo sapiens 0-7 25088930-0 2014 Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: ex vivo studies. Amoxicillin 120-131 albumin Homo sapiens 83-96 25898690-9 2015 Moreover, formation of BL-protein adducts is selective, as we recently demonstrated for amoxicillin, which mainly modifies albumin, transferrin, and immunoglobulin heavy and light chains in human serum. Amoxicillin 88-99 transferrin Homo sapiens 132-143 25720807-7 2015 Most ampicillin and/or amoxicillin-resistant E. coli isolates carried blaTEM-1 genes. Amoxicillin 23-34 beta-lactamase Escherichia coli 70-78 25826490-4 2015 However, effects of the combination of metronidazole with amoxicillin or spiramycin on the release and activation of MMP-2 and the balance MMP-2/TIMP-2 were rarely studied. Amoxicillin 58-69 matrix metallopeptidase 2 Homo sapiens 117-122 25826490-4 2015 However, effects of the combination of metronidazole with amoxicillin or spiramycin on the release and activation of MMP-2 and the balance MMP-2/TIMP-2 were rarely studied. Amoxicillin 58-69 matrix metallopeptidase 2 Homo sapiens 139-144 25826490-4 2015 However, effects of the combination of metronidazole with amoxicillin or spiramycin on the release and activation of MMP-2 and the balance MMP-2/TIMP-2 were rarely studied. Amoxicillin 58-69 TIMP metallopeptidase inhibitor 2 Homo sapiens 145-151 25456688-5 2014 All patients with a positive GAS rapid antigen test were treated with antibiotics (amoxicillin essentially) and cured without surgery. Amoxicillin 83-94 gastrin Homo sapiens 29-32 25566232-5 2014 Following amoxicillin administration, an increase in the proportion of amoxicillin resistant E. coli and a three-fold increase in the levels of bla TEM gene carriage was observed, an effect not observed in the other two treatment groups. Amoxicillin 10-21 beta-lactamase Escherichia coli 144-147 25088930-1 2014 This study addresses the detection and characterization of the modification of human serum albumin (HSA) by amoxicillin (AX) in ex vivo samples from healthy subjects under oral amoxicillin administration (acute intake of 1 g every 8 h for 48 h). Amoxicillin 108-119 albumin Homo sapiens 85-98 25088930-1 2014 This study addresses the detection and characterization of the modification of human serum albumin (HSA) by amoxicillin (AX) in ex vivo samples from healthy subjects under oral amoxicillin administration (acute intake of 1 g every 8 h for 48 h). Amoxicillin 121-123 albumin Homo sapiens 85-98 25088930-1 2014 This study addresses the detection and characterization of the modification of human serum albumin (HSA) by amoxicillin (AX) in ex vivo samples from healthy subjects under oral amoxicillin administration (acute intake of 1 g every 8 h for 48 h). Amoxicillin 177-188 albumin Homo sapiens 85-98 23962812-0 2014 Generalized pustular psoriasis triggered by amoxicillin in monozygotic twins with compound heterozygous IL36RN mutations: comment on the article by Navarini et al. Amoxicillin 44-55 interleukin 36 receptor antagonist Homo sapiens 104-110 24656634-12 2014 In addition, individuals with IL36RN mutations are very susceptible to GPP or GPP-related generalized pustulosis induced by drugs (e.g., amoxicillin), infections, pregnancy, or menstruation. Amoxicillin 137-148 interleukin 36 receptor antagonist Homo sapiens 30-36 24634909-4 2014 In addition, the sensor exhibited selectivity, as much smaller responses were obtained for high concentrations (~700 muM) of other commonly prescribed antibiotics such as amoxicillin, bleomycin and gentamicin. Amoxicillin 171-182 latexin Homo sapiens 117-120 24761684-0 2014 Modified sequential Helicobacter pylori eradication therapy using high dose omeprazole and amoxicillin in the initial phase in the extensive metaboliser Turkish patients for CYP2C19 polymorphism is ineffective. Amoxicillin 91-102 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 174-181 24029460-2 2013 It is evident that bentonite modified with hexadecyl trimethyl ammonium (DK1) can effectively remove amoxicillin from aqueous solution. Amoxicillin 101-112 immunoglobulin heavy diversity 5-12 Homo sapiens 73-76 23912886-0 2014 Group A streptococci are protected from amoxicillin-mediated killing by vesicles containing beta-lactamase derived from Haemophilus influenzae. Amoxicillin 40-51 beta-lactamase TEM-1 Haemophilus influenzae 92-106 23912886-8 2014 The hydrolysis of amoxicillin by beta-lactamase was estimated by an agar diffusion method. Amoxicillin 18-29 beta-lactamase TEM-1 Haemophilus influenzae 33-47 23912886-9 2014 RESULTS: We showed that OMVs released from beta-lactam-resistant M. catarrhalis and NTHi contain functional beta-lactamase that hydrolyses amoxicillin and protects GAS from killing by amoxicillin. Amoxicillin 139-150 beta-lactamase TEM-1 Haemophilus influenzae 108-122 23912886-9 2014 RESULTS: We showed that OMVs released from beta-lactam-resistant M. catarrhalis and NTHi contain functional beta-lactamase that hydrolyses amoxicillin and protects GAS from killing by amoxicillin. Amoxicillin 184-195 beta-lactamase TEM-1 Haemophilus influenzae 108-122 24940337-7 2013 Antibiotic susceptibility profile of ESBL isolates showed 100.0% resistance against Amoxicillin, Cotrimoxazole and Erythromycin. Amoxicillin 84-95 EsbL Escherichia coli 37-41 26619498-7 2013 Children initially prescribed amoxicillin or penicillin had higher odds of retreatment of GAS pharyngitis even after adjusting for age, sex, symptoms, and community-level covariates such as race, income, and education (odds ratio, 1.51; 95% confidence interval, 1.07-2.13). Amoxicillin 30-41 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 90-93 26619498-8 2013 CONCLUSIONS: Retreatment for GAS pharyngitis was uncommon and associated with receipt of amoxicillin or penicillin, although the impact of GAS carriage is unknown. Amoxicillin 89-100 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 29-32 24274894-13 2013 These ESBL - producer uropathogens showed high degree of resistance to ceftriaxone (100.0%), amoxycillin, fluoroquinolones and co-trimoxazole. Amoxicillin 93-104 EsbL Escherichia coli 6-10 24029460-3 2013 Batch experiments showed that the adsorption of amoxicillin onto DK1 fitted well to a pseudo second-order kinetic model with corresponding rate constants (0.0187 g/mg min at 20 C). Amoxicillin 48-59 immunoglobulin heavy diversity 5-12 Homo sapiens 65-68 24029460-5 2013 Our thermodynamic study suggested that the adsorption of amoxicillin onto DK1 was physisorptive and endothermic in nature. Amoxicillin 57-68 immunoglobulin heavy diversity 5-12 Homo sapiens 74-77 24029460-9 2013 Finally, DK1 was used to remove amoxicillin from wastewaters and the results showed 81.9% and 87.5% of amoxicillin was removed at 19.0 mg/L and 2.0 mg/L, respectively. Amoxicillin 32-43 immunoglobulin heavy diversity 5-12 Homo sapiens 9-12 24029460-9 2013 Finally, DK1 was used to remove amoxicillin from wastewaters and the results showed 81.9% and 87.5% of amoxicillin was removed at 19.0 mg/L and 2.0 mg/L, respectively. Amoxicillin 103-114 immunoglobulin heavy diversity 5-12 Homo sapiens 9-12 22446938-1 2012 An in vivo role of the multidrug resistant-associated protein (Mrp2) in rat hepatocytes was examined by immunocytochemistry (ICC) for amoxicillin (AMPC) by the use of the transporter-deficient Eisai hyperbilirubinemic rats (EHBR). Amoxicillin 134-145 ATP binding cassette subfamily C member 2 Rattus norvegicus 63-67 23991837-4 2013 In this work, molecular docking, molecular dynamic simulations, and relative free energy calculations were applied in order to get a comprehensive and thorough analysis of TEM-1/ampicillin and TEM-1/amoxicillin complexes. Amoxicillin 199-210 CD248 molecule Homo sapiens 193-198 23627344-3 2013 The current edition of the Uganda Clinical Guidelines recommends amoxicillin or cotrimoxazole as choice drugs for empirical treatment of community-acquired UTI. Amoxicillin 65-76 alpha-1-microglobulin/bikunin precursor Homo sapiens 156-159 22760341-6 2013 These results suggest that 3-day treatment with this clavulanate/amoxicillin preparation is expected to provide a valid means of treating pediatric pharyngolaryngitis and tonsillitis caused by Group A beta-hemolytic Streptococcus. Amoxicillin 65-76 amyloid beta precursor protein Homo sapiens 199-205 22710106-8 2012 In GNAs, resistance rates to amoxicillin, metronidazole, clindamycin, tetracycline, levofloxacin, and amoxicillin/clavulanate were 42.1, 0, 52.6, 53.3, 86.7 and 5.2%, respectively. Amoxicillin 29-40 GNAS complex locus Homo sapiens 3-7 24066120-7 2013 The amoxicillin plus TLR2/4 or TLR7/8 ligands showed significant differences, mainly in patients: AX+PAM+LPS induced a decrease in TLR2 and AX+R848 in TLR2, 4, 7 and 8 mRNA levels. Amoxicillin 4-15 toll like receptor 2 Homo sapiens 151-158 23302428-4 2012 AMX and MTZ were given for 7 days immediately after supragingival scaling or the last time of SPR. Amoxicillin 0-3 sepiapterin reductase Homo sapiens 94-97 22446938-1 2012 An in vivo role of the multidrug resistant-associated protein (Mrp2) in rat hepatocytes was examined by immunocytochemistry (ICC) for amoxicillin (AMPC) by the use of the transporter-deficient Eisai hyperbilirubinemic rats (EHBR). Amoxicillin 147-151 ATP binding cassette subfamily C member 2 Rattus norvegicus 63-67 22446938-7 2012 These results strongly suggest that AMPC taken up into the cytoplasm of the hepatocytes excretes via Mrp2 into the bile flow. Amoxicillin 36-40 ATP binding cassette subfamily C member 2 Rattus norvegicus 101-105 20978001-0 2011 Contribution of ROB-1 and PBP3 mutations to the resistance phenotype of a beta-lactamase-positive amoxicillin/clavulanic acid-resistant Haemophilus influenzae carrying plasmid pB1000 in Italy. Amoxicillin 98-110 Rob-1 Haemophilus influenzae 16-21 22428518-8 2011 Resistance of E. coli to antibiotics commonly used in our environment for UTI, namely, amoxicillin/ clavulanate, cotrimoxazole and amoxicillin were 100% each. Amoxicillin 87-98 alpha-1-microglobulin/bikunin precursor Homo sapiens 74-77 21716955-1 2011 OBJECTIVES: Currently established first line therapy of acute (presumed bacterial) rhinosinusitis (ARS) consists of 10 to 14 days of oral amoxicillin or cephalosporins. Amoxicillin 138-149 RIEG2 Homo sapiens 99-102 21035968-8 2011 Four novel variants (bla(OKP-A-13), bla(OKP-A-14), bla(OKP-A-15), and bla(OKP-A-16)) were identified among the 10 OKP beta-lactamase-producing K. pneumoniae isolates resistant to ampicillin, amoxicillin, oxacillin, cefalexin, and cefadroxil. Amoxicillin 191-202 TEM beta-lactamase Klebsiella pneumoniae 21-24 21266816-5 2011 METHODS: 48 patients with steroid-dependent UC were recruited for a 2-week treatment with amoxicillin, tetracycline, and metronidazole (ATM). Amoxicillin 90-101 ATM serine/threonine kinase Homo sapiens 136-139 22555328-3 2012 Although penicillin and amoxicillin are the first choice antibiotics in the case of a child suffering from pharyngotonsillitis with the proven presence of Group A beta-hemolytic Streptococcus (GAS), the number of orally administered doses and 10 days of therapy, considerably lower the compliance. Amoxicillin 24-35 galactosamine (N-acetyl)-6-sulfatase Homo sapiens 155-191 21747323-7 2011 In the meta-analysis, recurrence rates following penicillin or amoxicillin were consistent across studies (fixed-effect test for heterogeneity, P = 0.35), and the pooled rate (37.4% [95% CI: 28.8%-46.5%]) was higher than observed following a beta-lactamase resistant agent (odds ratio: 2.39 [95% CI: 1.18-4.81]). Amoxicillin 63-74 amyloid beta precursor protein Homo sapiens 240-246 20966089-6 2011 In addition, Kp869 exhibited a 16-fold higher amoxicillin resistance level related to a 36.4&emsp14;kb tandem duplication encompassing the chromosomal bla(SHV-11) gene, which was unstable in vitro. Amoxicillin 46-57 SHV-11 Klebsiella pneumoniae 159-165 20716322-6 2010 RESULTS: Amoxicillin induced activation and increases of perforin and granzyme B (P = 0.007 and P = 0.041 respectively) but not IFNgamma production in NK cells from patients. Amoxicillin 9-20 granzyme B Homo sapiens 70-80 20878012-5 2010 Our aim was to assess the functional changes of mDC and pDC harvested from an amoxicillin-hypersensitive 32-year-old woman who experienced a severe maculopapular exanthema as reflected in interleukin-6 (IL-6) production after stimulation with this drug and penicillin. Amoxicillin 78-89 chemokine (C-C motif) ligand 22 Mus musculus 48-51 20878012-5 2010 Our aim was to assess the functional changes of mDC and pDC harvested from an amoxicillin-hypersensitive 32-year-old woman who experienced a severe maculopapular exanthema as reflected in interleukin-6 (IL-6) production after stimulation with this drug and penicillin. Amoxicillin 78-89 interleukin 6 Homo sapiens 188-201 20878012-5 2010 Our aim was to assess the functional changes of mDC and pDC harvested from an amoxicillin-hypersensitive 32-year-old woman who experienced a severe maculopapular exanthema as reflected in interleukin-6 (IL-6) production after stimulation with this drug and penicillin. Amoxicillin 78-89 interleukin 6 Homo sapiens 203-207 20878012-10 2010 A positive dose-response curve for IL-6 after stimulation with amoxicillin and penicillin was observed for pDC, but not for mDC or BDC suspension. Amoxicillin 63-74 interleukin 6 Homo sapiens 35-39 20376628-13 2010 CONCLUSION: The results suggest that the CYP2C19 genotype contrary to MDR1 and IL-1B genotypes may have an impact on the efficacy of H. pylori eradication in peptic ulcer patients treated with pantoprazole in Polish Caucasian peptic ulcer patients administered pantoprazole, amoxicillin, and metronidazole. Amoxicillin 275-286 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 41-48 20300795-9 2010 There was obvious association between amoxicillin use and the carriage of altered pbp gene(s). Amoxicillin 38-49 polycystin 1, transient receptor potential channel interacting Homo sapiens 82-85 20307930-2 2010 A three-layer backpropagation neural network was optimized to predict and simulate the degradation of amoxicillin, ampicillin and cloxacillin in aqueous solution in terms of COD removal. Amoxicillin 102-113 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 174-177 19717236-2 2009 The optimum operating conditions for treatment of an aqueous solution containing 104, 105 and 103 mg/L amoxicillin, ampicillin, and cloxacillin, respectively was observed to be H(2)O(2)/COD molar ratio 1.5, H(2)O(2)/Fe(2+) molar ratio 20 and pH 3. Amoxicillin 103-114 small nuclear ribonucleoprotein polypeptides B and B1 Homo sapiens 186-189 19948346-0 2010 Organically modified MCM-type material preparation and its usage in controlled amoxicillin delivery. Amoxicillin 79-90 methylmalonyl-CoA mutase Homo sapiens 21-24 19948346-1 2010 MCM-41 was grafted with 3-aminopropyl trimethoxysilane (APTMS), 3-chloropropyltriethoxysilane (CPTMS) to give organic group modified samples, and l-tryptophane was covalently immobilized onto organic samples to improve the physicochemical properties of mesoporous silica to controlled amoxicillin delivery. Amoxicillin 285-296 methylmalonyl-CoA mutase Homo sapiens 0-3 19948346-3 2010 The results of amoxicillin release exhibited that 12.9wt% and 33.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with APTMS and pure MCM-41 after 24h, however, 41.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with CPTMS after 24h. Amoxicillin 82-93 methylmalonyl-CoA mutase Homo sapiens 135-138 19948346-3 2010 The results of amoxicillin release exhibited that 12.9wt% and 33.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with APTMS and pure MCM-41 after 24h, however, 41.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with CPTMS after 24h. Amoxicillin 82-93 methylmalonyl-CoA mutase Homo sapiens 162-165 19948346-3 2010 The results of amoxicillin release exhibited that 12.9wt% and 33.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with APTMS and pure MCM-41 after 24h, however, 41.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with CPTMS after 24h. Amoxicillin 82-93 methylmalonyl-CoA mutase Homo sapiens 162-165 19948346-3 2010 The results of amoxicillin release exhibited that 12.9wt% and 33.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with APTMS and pure MCM-41 after 24h, however, 41.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with CPTMS after 24h. Amoxicillin 82-93 methylmalonyl-CoA mutase Homo sapiens 135-138 19948346-3 2010 The results of amoxicillin release exhibited that 12.9wt% and 33.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with APTMS and pure MCM-41 after 24h, however, 41.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with CPTMS after 24h. Amoxicillin 82-93 methylmalonyl-CoA mutase Homo sapiens 162-165 19948346-3 2010 The results of amoxicillin release exhibited that 12.9wt% and 33.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with APTMS and pure MCM-41 after 24h, however, 41.0wt% impregnated amoxicillin could be released from the post-grafting MCM-41 with CPTMS after 24h. Amoxicillin 82-93 methylmalonyl-CoA mutase Homo sapiens 162-165 20194282-6 2010 Amoxicillin exposure within 30 days (odds ratio [OR]: 3.6 [95% confidence interval (CI): 1.6-8.2]) and 31 to 60 days (OR: 2.8 [95% CI: 1.0-7.5]) before UTI both were associated with ampicillin resistance. Amoxicillin 0-11 alpha-1-microglobulin/bikunin precursor Homo sapiens 152-155 20194282-8 2010 Amoxicillin exposure within 30 days of UTI was also associated with amoxicillin-clavulanate resistance (OR: 3.9 [95% CI: 1.8-8.7]). Amoxicillin 0-11 alpha-1-microglobulin/bikunin precursor Homo sapiens 39-42 23818792-4 2009 In addition, the isolates were tested for beta-lactamase production using disks impregnated with Nitrocefin and hyperproduction of beta-lactamase using amoxicillin (20 mug) and clavulanic acid (10 mug) disks. Amoxicillin 152-163 beta-lactamase Staphylococcus aureus 131-145 19285734-0 2009 Rate of eradication of group A beta-hemolytic streptococci in children with pharyngo-tonsillitis by amoxicillin and cefdinir. Amoxicillin 100-111 amyloid beta precursor protein Homo sapiens 29-35 19154548-2 2009 In this study, the frequency of circulating specific T cells was analyzed by interferon-gamma (IFN-gamma) enzyme-linked immunospot assay in 22 patients with an allergic MPE to amoxicillin (amox). Amoxicillin 176-187 interferon gamma Homo sapiens 77-93 19154548-2 2009 In this study, the frequency of circulating specific T cells was analyzed by interferon-gamma (IFN-gamma) enzyme-linked immunospot assay in 22 patients with an allergic MPE to amoxicillin (amox). Amoxicillin 176-187 interferon gamma Homo sapiens 95-104 19154548-2 2009 In this study, the frequency of circulating specific T cells was analyzed by interferon-gamma (IFN-gamma) enzyme-linked immunospot assay in 22 patients with an allergic MPE to amoxicillin (amox). Amoxicillin 176-180 interferon gamma Homo sapiens 77-93 19154548-2 2009 In this study, the frequency of circulating specific T cells was analyzed by interferon-gamma (IFN-gamma) enzyme-linked immunospot assay in 22 patients with an allergic MPE to amoxicillin (amox). Amoxicillin 176-180 interferon gamma Homo sapiens 95-104 19505232-4 2009 A beta-lactamase inhibitor with co-administration of a beta-lactam antibiotic has proven to be an effective treatment against antibiotic-resistant bacteria whose resistance is due to serine-based beta-lactamases (e.g., amoxicillin/clavulanic acid). Amoxicillin 219-230 amyloid beta precursor protein Homo sapiens 0-6 19743791-8 2009 Most of the isolates from UTI have high rates of resistance (> 80%) to the commonly used antibiotics such as ampicillin, amoxicillin, chloramphenicol, gentamicin, streptomycin, and trimethoprim-sulphamethoxazole; and in isolates from SSI to amoxicillin and trimethoprim-sulphamethoxazole. Amoxicillin 124-135 alpha-1-microglobulin/bikunin precursor Homo sapiens 26-29 19178404-9 2009 CONCLUSIONS: Levels of specific IgE antibodies tended to decrease over time in patients with immediate allergic reactions to amoxicillin. Amoxicillin 125-136 immunoglobulin heavy constant epsilon Homo sapiens 32-35 19743791-8 2009 Most of the isolates from UTI have high rates of resistance (> 80%) to the commonly used antibiotics such as ampicillin, amoxicillin, chloramphenicol, gentamicin, streptomycin, and trimethoprim-sulphamethoxazole; and in isolates from SSI to amoxicillin and trimethoprim-sulphamethoxazole. Amoxicillin 244-255 alpha-1-microglobulin/bikunin precursor Homo sapiens 26-29 18759995-9 2008 The third-generation cephalosporins cefixime and cefpodoxime, as well as amoxicillin plus clavulanic acid, continue to be very active against both BL-positive and BLNAR strains of H. influenzae, and thus remain useful treatment options for patients with respiratory tract infections. Amoxicillin 73-84 beta-lactamase TEM-1 Haemophilus influenzae 147-149 19476013-3 2009 RESULTS: With Flow-CAST, sensitivity varied for individual beta-lactam allergens from 16% for penicilloyl-polylysine to 33% for amoxicillin, reaching 50% when all 5 allergens were considered. Amoxicillin 128-139 calpastatin Homo sapiens 19-23 18940364-0 2008 Once-daily amoxicillin eradicates group a beta-hemolytic strep as well as penicillin twice a day. Amoxicillin 11-22 amyloid beta precursor protein Homo sapiens 40-46 18360841-9 2008 CONCLUSION: All amoxicillin-resistant isolates of H. influenzae are producing beta-Lactamase; and the rates of amoxicillin-resistant isolates are increasing over time. Amoxicillin 16-27 beta-lactamase TEM-1 Haemophilus influenzae 78-92 18331364-0 2008 Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy. Amoxicillin 82-93 CD63 molecule Homo sapiens 46-50 18331364-0 2008 Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy. Amoxicillin 82-93 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 55-61 18331364-4 2008 OBJECTIVE: The aim of the study was to compare the reliability of CD203c to CD63 for the diagnosis of amoxicillin (AX) allergy, which is nowadays the most frequent BL allergy. Amoxicillin 102-113 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 66-72 18331364-4 2008 OBJECTIVE: The aim of the study was to compare the reliability of CD203c to CD63 for the diagnosis of amoxicillin (AX) allergy, which is nowadays the most frequent BL allergy. Amoxicillin 102-113 CD63 molecule Homo sapiens 76-80 18331364-4 2008 OBJECTIVE: The aim of the study was to compare the reliability of CD203c to CD63 for the diagnosis of amoxicillin (AX) allergy, which is nowadays the most frequent BL allergy. Amoxicillin 115-117 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 66-72 18331364-4 2008 OBJECTIVE: The aim of the study was to compare the reliability of CD203c to CD63 for the diagnosis of amoxicillin (AX) allergy, which is nowadays the most frequent BL allergy. Amoxicillin 115-117 CD63 molecule Homo sapiens 76-80 18331364-14 2008 CONCLUSION: CD203c seems to be a more sensitive activation marker of basophils than CD63 for the diagnosis of amoxicillin allergy. Amoxicillin 110-121 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 12-18 18331364-14 2008 CONCLUSION: CD203c seems to be a more sensitive activation marker of basophils than CD63 for the diagnosis of amoxicillin allergy. Amoxicillin 110-121 CD63 molecule Homo sapiens 84-88 18505850-6 2008 All beta-lactamase-positive isolates were TEM-1, but five different promoter regions were identified, with Pdel being the most prevalent in both years, and Prpt being associated with the highest amoxicillin resistance. Amoxicillin 195-206 beta-lactamase TEM-1 Haemophilus influenzae 4-18 18443129-0 2008 Low beta-lactamase-negative ampicillin-resistant Haemophilus influenzae strains are best detected by testing amoxicillin susceptibility by the broth microdilution method. Amoxicillin 109-120 beta-lactamase TEM-1 Haemophilus influenzae 4-18 18443129-6 2008 By Etest, 15% of beta-lactamase-positive isolates were nonresistant to ampicillin or amoxicillin. Amoxicillin 85-96 beta-lactamase TEM-1 Haemophilus influenzae 17-31 17822730-5 2007 Amoxicillin up-regulated the expression of CYP11beta2 and CYP19 by more than 2-fold and induced estradiol production up to almost 3-fold. Amoxicillin 0-11 cytochrome P450 family 19 subfamily A member 1 Homo sapiens 58-63 18192681-6 2008 RESULTS: Amoxicillin-resistant (MIC 2 mg/L) and amoxicillin-susceptible (MIC 0.06 mg/L) isolates, belonging to the same strain, were observed in different biopsies in one patient (inter-niche heteroresistance). Amoxicillin 9-20 CD99 molecule (Xg blood group) Homo sapiens 32-37 18070972-6 2008 Escherichia coli harboring bla(CAD-1) exhibited resistance to penams (benzylpenicillin and amoxicillin) and remained susceptible to amoxicillin in combination with clavulanic acid. Amoxicillin 91-102 beta-lactamase Escherichia coli 27-30 18070972-6 2008 Escherichia coli harboring bla(CAD-1) exhibited resistance to penams (benzylpenicillin and amoxicillin) and remained susceptible to amoxicillin in combination with clavulanic acid. Amoxicillin 132-143 beta-lactamase Escherichia coli 27-30 18998749-8 2008 Several amoxicillin regimens also achieved a high likelihood of pharmacodynamic target attainment (91.8- 98.6%) when beta-lactamase-positive strains were excluded from the analysis. Amoxicillin 8-19 beta-lactamase TEM-1 Haemophilus influenzae 117-131 18250924-6 2007 An exception is the oral treatment of multidrug-resistant serotype 19A strains in children in the USA, as these are resistant to amoxicillin, oral cephalosporins, macrolides, clindamycin and co-trimoxazole. Amoxicillin 129-140 SLAM family member 7 Homo sapiens 67-70 17612058-11 2007 Among the 27 amoxicillin- and ceftiofur-resistant Salmonella isolates, the blacMY-2 gene was detected in 22 isolates. Amoxicillin 13-24 AmpC Escherichia coli 75-83 17664320-6 2007 Since both BLNAR and BLPACR strains exhibited the same MIC, this was due to the significantly lower (P < or = 0.012) amoxicillin concentrations from 4 h on in simulations with beta-lactamase positive versus negative strains, thus decreasing the time above MIC (T>MIC). Amoxicillin 120-131 beta-lactamase TEM-1 Haemophilus influenzae 179-193 17697203-9 2007 CONCLUSIONS: Polymorphism of MDR1 is one of the determinants of successful eradication of H. pylori by the triple therapy with lansoprazole, amoxicillin and clarithromycin, together with CYP2C19 genotype and bacterial susceptibility to clarithromycin. Amoxicillin 141-152 ATP binding cassette subfamily B member 1 Homo sapiens 29-33 17854115-1 2007 This study dealt with the potential of MEKC with LIF detection involving derivatization with sulfoindocyanine succinimidyl ester (Cy5) for the separation and determination of beta-lactam antibiotics (ampicillin, amoxicillin, cephradine, and cephalexin) in environmental water samples. Amoxicillin 212-223 LIF interleukin 6 family cytokine Homo sapiens 49-52 17877324-2 2007 Amoxicillin concentrations in RO and tap water varied between 1.18 and 1.29 mg/ml, and 1.09 and 1.22 mg/ml, respectively. Amoxicillin 0-11 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) Mus musculus 37-40 17532588-6 2007 When beta-lactamase was produced, the MICs of amoxicillin increased, but the activity of the other antibiotics was unchanged. Amoxicillin 46-57 beta-lactamase TEM-1 Haemophilus influenzae 5-19 16891323-3 2006 The penicillin-binding domain of PBP3 of beta-lactamase (BL)-negative, amoxicillin-resistant (BLNAR) isolates was sequenced. Amoxicillin 71-82 beta-lactamase TEM-1 Haemophilus influenzae 41-55 17428889-5 2007 beta-Lactamase production is highly prevalent worldwide and is associated with resistance to ampicillin and amoxicillin. Amoxicillin 108-119 beta-lactamase TEM-1 Haemophilus influenzae 0-14 17428889-6 2007 Strains with alterations in penicillin binding proteins, particularly PBP3 (beta-lactamase negative ampicillin resistant and beta-lactamase positive amoxicillin-clavulanate resistant), are increasing in prevalence, particularly in Japan, with increasing resistance to ampicillin, amoxicillin, amoxicillin-clavulanate, and many cephalosporins, limiting the efficacy of expanded-spectrum cephalosporins against meningitis and of many oral cephalosporins against other diseases. Amoxicillin 149-160 beta-lactamase TEM-1 Haemophilus influenzae 125-139 17298429-0 2007 Amoxicillin conjugates to HLA class I molecules and interferes with signalling through the ILT2/LIR-1/CD85j inhibitory receptor. Amoxicillin 0-11 leukocyte immunoglobulin like receptor B1 Homo sapiens 91-95 17298429-0 2007 Amoxicillin conjugates to HLA class I molecules and interferes with signalling through the ILT2/LIR-1/CD85j inhibitory receptor. Amoxicillin 0-11 leukocyte immunoglobulin like receptor B1 Homo sapiens 96-101 17298429-0 2007 Amoxicillin conjugates to HLA class I molecules and interferes with signalling through the ILT2/LIR-1/CD85j inhibitory receptor. Amoxicillin 0-11 leukocyte immunoglobulin like receptor B1 Homo sapiens 102-107 17298429-4 2007 METHODS: We have evaluated, at the biochemical and cellular level, the ability of amoxicillin (AX) conjugate to HLA class I molecules and to interfere with the inhibitory signal delivered by the HLA class I receptor ILT2/LIR-1/CD85j. Amoxicillin 82-93 leukocyte immunoglobulin like receptor B1 Homo sapiens 216-220 17298429-4 2007 METHODS: We have evaluated, at the biochemical and cellular level, the ability of amoxicillin (AX) conjugate to HLA class I molecules and to interfere with the inhibitory signal delivered by the HLA class I receptor ILT2/LIR-1/CD85j. Amoxicillin 82-93 leukocyte immunoglobulin like receptor B1 Homo sapiens 221-226 17298429-4 2007 METHODS: We have evaluated, at the biochemical and cellular level, the ability of amoxicillin (AX) conjugate to HLA class I molecules and to interfere with the inhibitory signal delivered by the HLA class I receptor ILT2/LIR-1/CD85j. Amoxicillin 82-93 leukocyte immunoglobulin like receptor B1 Homo sapiens 227-232 17298429-4 2007 METHODS: We have evaluated, at the biochemical and cellular level, the ability of amoxicillin (AX) conjugate to HLA class I molecules and to interfere with the inhibitory signal delivered by the HLA class I receptor ILT2/LIR-1/CD85j. Amoxicillin 95-97 leukocyte immunoglobulin like receptor B1 Homo sapiens 216-220 17298429-4 2007 METHODS: We have evaluated, at the biochemical and cellular level, the ability of amoxicillin (AX) conjugate to HLA class I molecules and to interfere with the inhibitory signal delivered by the HLA class I receptor ILT2/LIR-1/CD85j. Amoxicillin 95-97 leukocyte immunoglobulin like receptor B1 Homo sapiens 221-226 17298429-4 2007 METHODS: We have evaluated, at the biochemical and cellular level, the ability of amoxicillin (AX) conjugate to HLA class I molecules and to interfere with the inhibitory signal delivered by the HLA class I receptor ILT2/LIR-1/CD85j. Amoxicillin 95-97 leukocyte immunoglobulin like receptor B1 Homo sapiens 227-232 18323331-8 2007 In this study, twice-daily (BID) MFNS 200 microg produced statistically greater improvements in overall symptoms and most individual symptoms compared with amoxicillin or placebo, even though Amoxicillin is not the one recommended by the French guidelines for this indication. Amoxicillin 192-203 BH3 interacting domain death agonist Homo sapiens 28-31 16940114-1 2006 The antimicrobial activity of amoxicillin against TEM-1-expressing strains could be fully recovered when bacteria were preincubated with sublethal doses of an antibacterial peptide derivative. Amoxicillin 30-41 CD248 molecule Homo sapiens 50-55 16870757-6 2006 A recombinant Escherichia coli strain carrying the bla(FUS-1) gene exhibited resistance to amoxicillin with a moderate decrease in the MICs with clavulanic acid. Amoxicillin 91-102 beta-lactamase Escherichia coli 51-54 16627568-7 2006 Our results indicate that the substrate selectivity of hPEPT1 is: Gly-Sar > NAAG, delta-ALA, bestatin > cefadroxil, cephalexin > ampicillin, amoxicillin. Amoxicillin 150-161 solute carrier family 15 member 1 Homo sapiens 55-61 16999056-5 2006 Follow-up in the bacteriology population on days 17 through 28 revealed that amoxicillin/clavulanate therapy was successful in 345 of 371 patients with S pneumoniae infection (93.0%) and in 36 of 37patients with PRSP infection (97.3%), including 7 of 8 patients (87.5%) whose amoxicillin/clavulanic acid MICs were 4/2 microg/ml or higher. Amoxicillin 77-88 HtrA serine peptidase 3 Homo sapiens 212-216 16890779-7 2006 SA-2 also redirected the in vitro differentiation of either Dermatophagoides pteronyssinus group 1 or amoxicillin-specific T(H)2 cells toward the T(H)1/T(H)0 phenotype, with parallel downregulation of GATA-3 and upregulation of T-box expressed in T cells transcription factors. Amoxicillin 102-113 stromal antigen 2 Homo sapiens 0-4 16842467-12 2006 CONCLUSIONS: Triple therapy with esomeprazole, rifabutin and amoxicillin and high-dose omeprazole/amoxicillin are comparable and effective and safe for rescue therapy of H. pylori regardless of the patient"s CYP2C19 genotype. Amoxicillin 61-72 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 208-215 16842467-12 2006 CONCLUSIONS: Triple therapy with esomeprazole, rifabutin and amoxicillin and high-dose omeprazole/amoxicillin are comparable and effective and safe for rescue therapy of H. pylori regardless of the patient"s CYP2C19 genotype. Amoxicillin 98-109 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 208-215 16131529-7 2005 The expression of genes coding for Paneth cell products (defensins, matrilysin, and phospholipase A2) was significantly downregulated by the Clamoxyl treatment. Amoxicillin 141-149 matrix metallopeptidase 7 Rattus norvegicus 68-78 16434549-4 2006 The objective of the current study was to examine the kinetics of amoxicillin and cefaclor interactions with human renal transporters human organic anion transporter 1 (hOAT1), human peptide transporter 1 (hPepT1), and human peptide transporter 2 (hPepT2) in detail, both as substrates and as inhibitors. Amoxicillin 66-77 solute carrier family 22 member 6 Homo sapiens 169-174 16434549-4 2006 The objective of the current study was to examine the kinetics of amoxicillin and cefaclor interactions with human renal transporters human organic anion transporter 1 (hOAT1), human peptide transporter 1 (hPepT1), and human peptide transporter 2 (hPepT2) in detail, both as substrates and as inhibitors. Amoxicillin 66-77 solute carrier family 15 member 1 Homo sapiens 183-204 16434549-4 2006 The objective of the current study was to examine the kinetics of amoxicillin and cefaclor interactions with human renal transporters human organic anion transporter 1 (hOAT1), human peptide transporter 1 (hPepT1), and human peptide transporter 2 (hPepT2) in detail, both as substrates and as inhibitors. Amoxicillin 66-77 solute carrier family 15 member 2 Homo sapiens 225-246 16434549-4 2006 The objective of the current study was to examine the kinetics of amoxicillin and cefaclor interactions with human renal transporters human organic anion transporter 1 (hOAT1), human peptide transporter 1 (hPepT1), and human peptide transporter 2 (hPepT2) in detail, both as substrates and as inhibitors. Amoxicillin 66-77 solute carrier family 15 member 2 Homo sapiens 248-254 16434549-6 2006 Amoxicillin and cefaclor inhibited hOAT1-mediated [(3)H]para-aminohippuric acid uptake (K(i) = 11.0 and 1.15 mM, respectively). Amoxicillin 0-11 solute carrier family 22 member 6 Homo sapiens 35-40 16434549-8 2006 Amoxicillin and cefaclor competitively inhibited hPepT2-mediated [(3)H]glycylsarcosine uptake (K(i) = 733 and 65 muM, respectively), whereas much lower affinity for hPepT1 was observed with both antibiotics. Amoxicillin 0-11 solute carrier family 15 member 2 Homo sapiens 49-55 16434549-8 2006 Amoxicillin and cefaclor competitively inhibited hPepT2-mediated [(3)H]glycylsarcosine uptake (K(i) = 733 and 65 muM, respectively), whereas much lower affinity for hPepT1 was observed with both antibiotics. Amoxicillin 0-11 latexin Homo sapiens 113-116 16617062-1 2006 OBJECTIVES: To study yearly changes in resistance and to identify ftsI mutations in beta-lactamase-non-producing ampicillin-resistant (BLNAR) and TEM-1 beta-lactamase-producing amoxicillin/clavulanic acid-resistant (BLPACR) isolates of Haemophilus influenzae from patients with meningitis. Amoxicillin 177-188 beta-lactamase TEM-1 Haemophilus influenzae 152-166 16780227-7 2006 Eight amoxicillin-resistant isolates had TEM-1 beta-lactamase. Amoxicillin 6-17 TEM-1 beta-lactamase Escherichia coli 41-61 16434549-8 2006 Amoxicillin and cefaclor competitively inhibited hPepT2-mediated [(3)H]glycylsarcosine uptake (K(i) = 733 and 65 muM, respectively), whereas much lower affinity for hPepT1 was observed with both antibiotics. Amoxicillin 0-11 solute carrier family 15 member 1 Homo sapiens 165-171 16434549-9 2006 Direct uptake studies demonstrated that amoxicillin and cefaclor were transported by hPepT1 and hPepT2. Amoxicillin 40-51 solute carrier family 15 member 1 Homo sapiens 85-91 16434549-9 2006 Direct uptake studies demonstrated that amoxicillin and cefaclor were transported by hPepT1 and hPepT2. Amoxicillin 40-51 solute carrier family 15 member 2 Homo sapiens 96-102 16434549-10 2006 Kinetic analysis showed that hPepT2-mediated uptake of both drugs was saturable with K(m) of 1.04 mM for amoxicillin and 70.2 muM for cefaclor. Amoxicillin 105-116 solute carrier family 15 member 2 Homo sapiens 29-35 16434549-11 2006 hPepT2, and to a lesser extent hPepT1, may play an important role in apical transport of amoxicillin and cefaclor in the renal tubule. Amoxicillin 89-100 solute carrier family 15 member 2 Homo sapiens 0-6 16434549-11 2006 hPepT2, and to a lesser extent hPepT1, may play an important role in apical transport of amoxicillin and cefaclor in the renal tubule. Amoxicillin 89-100 solute carrier family 15 member 1 Homo sapiens 31-37 16330217-3 2006 The data collected were compared with those of a previous trial performed in the same setting and documenting the effectiveness and advantages associated with the use of amoxicillin against community-acquired uncomplicated urinary tract infections (UTI). Amoxicillin 170-181 alpha-1-microglobulin/bikunin precursor Homo sapiens 249-252 16388032-7 2006 Post-treatment resistance to amoxicillin was detected in 1.6% of 63 strains. Amoxicillin 29-40 solute carrier family 35 member G1 Homo sapiens 0-4 16131529-7 2005 The expression of genes coding for Paneth cell products (defensins, matrilysin, and phospholipase A2) was significantly downregulated by the Clamoxyl treatment. Amoxicillin 141-149 phospholipase A2 group IB Rattus norvegicus 84-100 15976341-11 2005 CONCLUSIONS: The availability of CRP and WBC data during initial consultation greatly reduced prescription of amoxicillin, but had a lesser effect on newer, potent, broad spectrum antibiotics. Amoxicillin 110-121 C-reactive protein Homo sapiens 33-36 16270121-8 2005 The use of amoxicillin also influenced the intestinal microbiota, significantly decreasing the CFU of Bifidobacterium spp. Amoxicillin 11-22 histocompatibility minor 13 Homo sapiens 118-121 15567297-5 2005 Ceftibuten, dicloxacillin, amoxicillin, metampicillin, cloxacillin, ampicillin, cefixime, cefamandole, oxacillin and cefmetazole interacted with PEPT2 with medium affinity (K(i)=0.1-5mM). Amoxicillin 27-38 solute carrier family 15 member 2 Homo sapiens 145-150 16117975-15 2005 A new formulation of amoxicillin/clavulanate given 2000/125 mg BID is expected to eradicate isolates of S pneumoniae at an amoxicillin MIC < or = 4 microg/mL. Amoxicillin 21-32 BH3-interacting domain death agonist Meleagris gallopavo 63-66 15736403-10 2004 Bcl-2 expression was seen only in the control group and FasL was never seen, while the expression of TNFR1, Fas and caspase-3, -8 and -9 was seen in the amoxicillin-treated group, clarithromycin-treated group, amoxicillin and clarithromycin-treated group and the positive control group. Amoxicillin 210-221 tumor necrosis factor receptor superfamily, member 1b Mus musculus 101-106 15736403-10 2004 Bcl-2 expression was seen only in the control group and FasL was never seen, while the expression of TNFR1, Fas and caspase-3, -8 and -9 was seen in the amoxicillin-treated group, clarithromycin-treated group, amoxicillin and clarithromycin-treated group and the positive control group. Amoxicillin 210-221 caspase 3 Mus musculus 116-136 15736403-10 2004 Bcl-2 expression was seen only in the control group and FasL was never seen, while the expression of TNFR1, Fas and caspase-3, -8 and -9 was seen in the amoxicillin-treated group, clarithromycin-treated group, amoxicillin and clarithromycin-treated group and the positive control group. Amoxicillin 153-164 B cell leukemia/lymphoma 2 Mus musculus 0-5 12208796-7 2002 C-reactive protein levels were reduced (P=0.03) in unstable angina patients receiving amoxicillin, and fibrinogen was reduced in both patient groups receiving antibiotics (P=0.06). Amoxicillin 86-97 C-reactive protein Homo sapiens 0-18 15736403-10 2004 Bcl-2 expression was seen only in the control group and FasL was never seen, while the expression of TNFR1, Fas and caspase-3, -8 and -9 was seen in the amoxicillin-treated group, clarithromycin-treated group, amoxicillin and clarithromycin-treated group and the positive control group. Amoxicillin 153-164 Fas ligand (TNF superfamily, member 6) Mus musculus 56-60 15736403-10 2004 Bcl-2 expression was seen only in the control group and FasL was never seen, while the expression of TNFR1, Fas and caspase-3, -8 and -9 was seen in the amoxicillin-treated group, clarithromycin-treated group, amoxicillin and clarithromycin-treated group and the positive control group. Amoxicillin 153-164 tumor necrosis factor receptor superfamily, member 1b Mus musculus 101-106 15736403-10 2004 Bcl-2 expression was seen only in the control group and FasL was never seen, while the expression of TNFR1, Fas and caspase-3, -8 and -9 was seen in the amoxicillin-treated group, clarithromycin-treated group, amoxicillin and clarithromycin-treated group and the positive control group. Amoxicillin 153-164 caspase 3 Mus musculus 116-136 15138324-1 2004 A case of acute ischaemic colitis, confirmed by colonoscopy and colon biopsy, caused by IgE mediated allergy to amoxicillin is presented. Amoxicillin 112-123 immunoglobulin heavy constant epsilon Homo sapiens 88-91 15036240-0 2004 Effects of amoxicillin on cytokine and osteocalcin expression in bone tissue during experimental acute otitis media. Amoxicillin 11-22 bone gamma-carboxyglutamate protein Homo sapiens 39-50 15078004-0 2004 Effect of multiple doses of clarithromycin and amoxicillin on IL-6, IFNgamma and IL-10 plasma levels in patients with community acquired pneumonia. Amoxicillin 47-58 interleukin 6 Homo sapiens 62-66 15078004-0 2004 Effect of multiple doses of clarithromycin and amoxicillin on IL-6, IFNgamma and IL-10 plasma levels in patients with community acquired pneumonia. Amoxicillin 47-58 interleukin 10 Homo sapiens 81-86 15078004-8 2004 In patients treated with amoxicillin a significant decrease in IL-6 plasma levels was observed at the 7th day of therapy, probably in relation to the resolution of inflammatory symptoms. Amoxicillin 25-36 interleukin 6 Homo sapiens 63-67 12435677-9 2002 The index of surviving bacteria showed the existence of mixed concentration- and time-dependent actions of amoxicillin (in the presence of clavulanate) which varied as a function of the magnitude of beta-lactamase production by the test strains. Amoxicillin 107-118 beta-lactamase Escherichia coli 199-213 12650031-4 2002 After treatment for H. pylori infection (omeprazole, clarithromycin, amoxycillin), clinical symptoms improved consistently, the serum gastrin level was repeteadly quite normal and hematologic and iron profiles were within the normal range. Amoxicillin 69-80 gastrin Homo sapiens 134-141 15362088-8 2004 Amoxycillin was being used widely to treat UTI in pregnancy in spite of high prevalence of resistance. Amoxicillin 0-11 alpha-1-microglobulin/bikunin precursor Homo sapiens 43-46 15017629-3 2004 The aim of this study was to investigate whether IL-1beta polymorphism is associated with eradication rates of H. pylori by triple therapy with a proton pump inhibitor (PPI), amoxicillin, and clarithromycin. Amoxicillin 175-186 interleukin 1 beta Homo sapiens 49-57 15017629-8 2004 CONCLUSIONS: IL-1beta-511 polymorphism is one of the determinants of successful eradication of H. pylori using triple therapy with a PPI, amoxicillin, and clarithromycin, together with CYP2C19 genotype and bacterial resistance to clarithromycin. Amoxicillin 138-149 interleukin 1 beta Homo sapiens 13-21 12739920-1 2003 The purpose of this study was to compare the bacteriologic and clinical efficacy of oral penicillin versus amoxicillin as first-line therapy for group A beta-hemolytic streptococcal (GABHS) tonsillopharyngitis. Amoxicillin 107-118 amyloid beta precursor protein Homo sapiens 151-157 12724036-2 2003 Co-administration of the antibiotics amoxicillin and metronidazole (AMPC-MET) significantly increased the area under the plasma concentration versus time curve (AUC) of PF, whereas it markedly decreased that of PM-I, to 2.6% of the normal AUC by administration of a single dose, and less than 1% by a 3-day pretreatment. Amoxicillin 37-48 mannose phosphate isomerase Rattus norvegicus 211-215 12504368-9 2002 The percentage of PRP was 48.6% with 17.1% of intermediate-amoxicilline and 14.3% intermediate-cefotaxime strains. Amoxicillin 59-71 prion protein Homo sapiens 18-21 12121904-5 2002 Transformation experiments with cloned pbp genes isolated from one of the resistant isolates demonstrated a stepwise development of amoxicillin resistance involving penicillin-binding proteins (PBPs) 2X, 2B, and 1A. Amoxicillin 132-143 polycystin 1, transient receptor potential channel interacting Homo sapiens 39-42 11744606-10 2002 In contrast, probenecid effectively inhibited the transport of PAH, Ro 64-0802, and amoxicillin via hOAT1. Amoxicillin 84-95 solute carrier family 22 member 6 Homo sapiens 100-105 11959556-0 2002 Effects of amino acid alterations in penicillin-binding proteins (PBPs) 1a, 2b, and 2x on PBP affinities of penicillin, ampicillin, amoxicillin, cefditoren, cefuroxime, cefprozil, and cefaclor in 18 clinical isolates of penicillin-susceptible, -intermediate, and -resistant pneumococci. Amoxicillin 132-143 polycystin 1, transient receptor potential channel interacting Homo sapiens 66-69 12039897-3 2002 Resistance to amoxicillin was found in one isolate (MIC = 1.5 mg/L) from an untreated patient, and resistance to cefixime in two isolates from each group (P = 0.18). Amoxicillin 14-25 growth differentiation factor 15 Homo sapiens 52-59 11908634-9 2002 In addition, when recombinant human lactoferrin was used in combination with low doses of amoxicillin or tetracycline, there was an enhancement in gastritis-reducing activity. Amoxicillin 90-101 lactotransferrin Bos taurus 36-47 11176244-7 2001 In contrast, once-daily amoxicillin therapy appears to be effective, is inexpensive, and has a narrower spectrum of antimicrobial activity; if these findings are confirmed by additional investigations, it could become an alternative regimen for the treatment of pharyngitis caused by group A beta-hemolytic streptococci. Amoxicillin 24-35 amyloid beta precursor protein Homo sapiens 290-296 11746950-0 2001 Fine structural recognition specificities of IgE antibodies distinguishing amoxicilloyl and amoxicillanyl determinants in allergic subjects. Amoxicillin 92-105 immunoglobulin heavy constant epsilon Homo sapiens 45-48 11240980-11 2001 Re-treatment of H pylori infection with dual high-dose lansoprazole-amoxicillin therapy succeeded in 30 of 31 patients with extensive metabolizer genotype of CYP2C19. Amoxicillin 68-79 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 158-165 10898697-3 2000 All variants obtained by submitting an Escherichia coli strain that contains a bla(TEM-1) gene to fluctuating challenge with both ceftazidime and amoxicillin contained only mutations previously detected in naturally occurring beta-lactamases. Amoxicillin 146-157 hypothetical protein Escherichia coli 83-88 11482742-6 2001 Proton pump inhibitor (PPI)-based triple therapy regimens including clarithromycin, amoxicillin and/or nitroimidazoles are highly effective and well tolerated in elderly patients, particularly if therapy is of a short duration and low doses of both the PPI and clarithromycin are used. Amoxicillin 84-95 ATPase H+/K+ transporting subunit alpha Homo sapiens 0-11 10872651-0 2000 Cure of refractory duodenal ulcer and infection caused by Helicobacter pylori by high doses of omeprazole and amoxicillin in a homozygous CYP2C19 extensive metabolizer patient. Amoxicillin 110-121 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 138-145 14538105-1 2000 This article elaborates on the important recent developments in the enzymatic transformation of penicillins to 6-aminopenicillanic acid (6-APA), which is the basic raw material for the industrial production of semisynthetic penicillins such as amoxycillin and ampicillin. Amoxicillin 244-255 glutamyl aminopeptidase Homo sapiens 139-142 10872651-8 2000 Dual treatment with a sufficient dose of a proton pump inhibitor plus amoxicillin could cure H pylori infection even after the failure to cure H pylori infection by a usual proton pump inhibitor-based triple therapy in patients with the wt/wt homozygous extensive metabolizer genotype of CYP2C19. Amoxicillin 70-81 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 288-295 10573961-8 1999 Recently, the emergence of E. coli strain resistant to combination of amoxycillin and clavulanate, due to hyperproduction of TEM-1 beta-lactamase, was observed. Amoxicillin 70-81 TEM-1 beta-lactamase Escherichia coli 125-145 10793927-4 2000 CASE REPORT: A 4-year-old child was admitted for a right lower lobe pneumonia, with very high values of white blood cell count and CRP, worsening despite a treatment with high doses of amoxicillin, then with cefotaxime and vancomycin. Amoxicillin 185-196 C-reactive protein Homo sapiens 131-134 11810535-10 2000 The 50% curative doses (CD50) of amoxicillin and minocycline were 8.7 mg/kg and 3.1 mg/kg, respectively. Amoxicillin 33-44 intercellular adhesion molecule 5, telencephalin Mus musculus 24-28 10348183-5 1999 The fraction containing amoxicillin was concentrated on the analytical RP-C18 column. Amoxicillin 24-35 RNA polymerase II, I and III subunit H Homo sapiens 71-77 9867757-3 1998 OBJECTIVE: To investigate whether CYP2C19 genotype status is associated with cure rates for Helicobacterpylori infection and peptic ulcer achieved by using dual therapy with omeprazole and amoxicillin. Amoxicillin 189-200 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 34-41 9867757-11 1998 CONCLUSION: The results of the genotyping test for CYP2C19 seem to predict cure of H. pylori infection and peptic ulcer in patients who receive dual therapy with omeprazole and amoxicillin. Amoxicillin 177-188 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 51-58 9795787-7 1998 Amoxicillin resistance was due to production of TEM1 beta-lactamase. Amoxicillin 0-11 TEM-1 beta-lactamase Escherichia coli 48-67 9660985-4 1998 beta-Lactamase activity in the beta-lactamase-positive strain changed over time parallel to viability, decreasing with amoxicillin-clavulanic acid or vancomycin and increasing in the amoxicillin and control groups. Amoxicillin 119-130 beta-lactamase Staphylococcus aureus 0-14 9660985-4 1998 beta-Lactamase activity in the beta-lactamase-positive strain changed over time parallel to viability, decreasing with amoxicillin-clavulanic acid or vancomycin and increasing in the amoxicillin and control groups. Amoxicillin 119-130 beta-lactamase Staphylococcus aureus 31-45 9660985-5 1998 Clavulanic acid concentrations achievable in serum that changed over time allowed amoxicillin to act against the beta-lactamase-producing methicillin-resistant S. aureus to a similar extent as vancomycin. Amoxicillin 82-93 beta-lactamase Staphylococcus aureus 113-127 9337451-8 1997 Amoxicillin 50 mg/kg/d plus bismuth subsalicylate (< 10 y, 262 mg; > 10 y, 525 mg qid) or bismuth subcitrate (< 12 y, 120 mg; > 12 y, 240 mg bid) can be used for 6 weeks. Amoxicillin 0-11 BH3 interacting domain death agonist Homo sapiens 153-156 9093433-5 1997 Resistance to amoxycillin was due to production of TEM-1 (89%) and TEM-2 (11%). Amoxicillin 14-25 CD248 molecule Homo sapiens 51-56 9440054-10 1997 In alternative, omeprazole, clarithromycin, amoxicillin (OCA) has been also suggested to overcome the problem of metronidazole resistance, however recent studies seem to indicate that resistance to metronidazole does not seem to significantly influence outcome of OCT. Amoxicillin 44-55 plexin A2 Homo sapiens 264-267 9109139-5 1997 INTERVENTIONS: The amoxicillin dosage was 20 mg/kg/day either bid or qd. Amoxicillin 19-30 BH3 interacting domain death agonist Homo sapiens 62-65 9093433-5 1997 Resistance to amoxycillin was due to production of TEM-1 (89%) and TEM-2 (11%). Amoxicillin 14-25 RASD family member 2 Homo sapiens 67-72 8585554-2 1995 Nearly 100% of clinical isolates of Moraxella catarrhalis now produce beta-lactamase, an enzyme that renders this pathogen resistant to such agents as penicillin, ampicillin, and amoxicillin. Amoxicillin 179-190 beta-lactamase TEM-1 Haemophilus influenzae 70-84 8961060-4 1996 A recent course of antibiotics, especially ampicillin/amoxycillin, was significantly (P < 0.05) more common in the beta+ group (beta+ 17/34, beta- 3/34). Amoxicillin 54-65 eukaryotic translation elongation factor 1 beta 2 pseudogene 2 Homo sapiens 118-154 8839869-6 1996 Nine of the 11 alleles, responsible for the A2, Ax, Ael, cis-AB, Bx, and Bel phenotypes, were presumed to be generated from common ABO alleles by single nucleotide mutations such as nonsynonymous substitution, deletion, or insertion. Amoxicillin 48-50 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Homo sapiens 131-134 9124843-0 1996 Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate. Amoxicillin 60-71 beta-lactamase TEM-1 Haemophilus influenzae 24-38 9124843-4 1996 A PAE of 0.8 h was found for amoxicillin (four times the MIC) against a beta-lactamase-negative strain of H. influenzae (generation time, 26.3 min) and a PAE of 1.74 h was found for amoxicillin-clavulanate (twice the MIC) against a beta-lactamase-positive strain (generation time, 32.2 min). Amoxicillin 29-40 beta-lactamase TEM-1 Haemophilus influenzae 72-86 9124843-8 1996 The PLIE was related to the amount of beta-lactamase produced and required the presence of amoxicillin in the initial exposure period. Amoxicillin 91-102 beta-lactamase TEM-1 Haemophilus influenzae 38-52 7761138-3 1995 Amoxicillin remains the drug of choice for treatment of AOM. Amoxicillin 0-11 collagen type II alpha 1 chain Homo sapiens 56-59 8173146-10 1994 For those with symptomatic UTI, we recommend amoxicillin 500 mg tid for three days. Amoxicillin 45-56 alpha-1-microglobulin/bikunin precursor Homo sapiens 27-30 8775008-9 1995 One month after completion of treatment of peptic ulcer patients for H. pylori infection with lansoprazole and benexate HCl betadex plus amoxicillin, 6/9 (67%) patients showed positive to negative conversion of the tissue IgA antibody, in contrast to no IgG antibody seroconversion. Amoxicillin 137-148 CD79a molecule Homo sapiens 222-225 8040112-5 1994 Organisms with type C beta-lactamase were less susceptible than those with type A enzyme to piperacillin/tazobactam and amoxycillin/tazobactam in disc and MIC tests, and to co-amoxiclav in disc tests only. Amoxicillin 120-131 beta-lactamase Staphylococcus aureus 22-36 8047854-9 1994 The growing resistance of H. influenzae and M. catarrhalis to amoxycillin, due to beta-lactamase production, increases the risk of treatment failure of acute and serous otitis media. Amoxicillin 62-73 Beta lactamase Pseudomonas aeruginosa 82-96 8047854-10 1994 By adding a beta-lactamase inhibitor (clavulanic acid) to amoxycillin, or using second-generation cephalosporins, clearance can be achieved. Amoxicillin 58-69 Beta lactamase Pseudomonas aeruginosa 12-26 8262865-6 1993 Thus, the MICs of piperacillin or amoxycillin with tazobactam or clavulanate were only two- to four-fold higher for beta-lactamase producers than non-producers at low inocula (10(4) cfu), but this differential increased to 6- to 16-fold at high inocula (10(6) cfu). Amoxicillin 34-45 beta-lactamase Staphylococcus aureus 116-130 1818798-0 1991 Antibacterial activities of amoxicillin alone and in combination with clavulanic acid correlated with beta-lactamase production. Amoxicillin 28-39 beta-lactamase TEM-1 Haemophilus influenzae 102-116 8499823-1 1993 OBJECTIVE: To evaluate treatment of group A beta haemolytic streptococcal pharyngitis with amoxycillin once daily compared with phenoxymethylpenicillin three or four times a day. Amoxicillin 91-102 amyloid beta precursor protein Homo sapiens 42-48 8499823-10 1993 CONCLUSIONS: These findings support the hypothesis that amoxycillin once daily is as effective as phenoxymethylpenicillin in the treatment of group A beta haemolytic streptococcal pharyngitis. Amoxicillin 56-67 amyloid beta precursor protein Homo sapiens 148-154 8432315-3 1993 Forty-six percent of the TEM-1 producing strains were able to transfer this resistance to E. coli J62-2 at 37 degrees C. Analysis of the resulting transconjugants revealed that the degree of resistance to amoxycillin and amoxycillin in combination with clavulanic acid was related to the specific activity of the TEM-1 beta-lactamase. Amoxicillin 205-216 hypothetical protein Escherichia coli 25-30 8432315-3 1993 Forty-six percent of the TEM-1 producing strains were able to transfer this resistance to E. coli J62-2 at 37 degrees C. Analysis of the resulting transconjugants revealed that the degree of resistance to amoxycillin and amoxycillin in combination with clavulanic acid was related to the specific activity of the TEM-1 beta-lactamase. Amoxicillin 221-232 hypothetical protein Escherichia coli 25-30 1803992-1 1991 An isolate of Serratia marcescens that produced both an inducible chromosomal and a plasmid-mediated TEM-1 beta-lactamase was resistant to ampicillin and amoxicillin and also demonstrated decreased susceptibility to extended-spectrum beta-lactam antibiotics (ESBAs). Amoxicillin 154-165 TEM-1 Serratia marcescens 101-106 8262865-1 1993 beta-Lactamase production protects Staphylococcus aureus against piperacillin and amoxycillin. Amoxicillin 82-93 beta-lactamase Staphylococcus aureus 0-14 8096833-9 1993 The in vitro incubation of PMNs with R and amoxicillin (100 micrograms/ml) potentiated the positive effect of amoxicillin on adhesion and the antibiotic counterbalanced the negative effect of R on CD16 expression. Amoxicillin 43-54 Fc gamma receptor IIIa Homo sapiens 197-201 1818798-5 1991 In general, beta-lactamase nonproducers were more susceptible to amoxicillin than beta-lactamase producers. Amoxicillin 65-76 beta-lactamase TEM-1 Haemophilus influenzae 12-26 1818798-6 1991 For beta-lactamase producers, clavulanic acid decreased the MICs of amoxicillin prominently in strains of Neisseria gonorrhoeae, Haemophilus influenzae, Escherichia coli, K. pneumoniae, P. mirabilis, Enterobacter cloacae and Bacteroides fragilis, when combining clavulanic acid with amoxicillin in the ratio of 1:2. Amoxicillin 68-79 beta-lactamase Neisseria gonorrhoeae 4-18 1818798-6 1991 For beta-lactamase producers, clavulanic acid decreased the MICs of amoxicillin prominently in strains of Neisseria gonorrhoeae, Haemophilus influenzae, Escherichia coli, K. pneumoniae, P. mirabilis, Enterobacter cloacae and Bacteroides fragilis, when combining clavulanic acid with amoxicillin in the ratio of 1:2. Amoxicillin 283-294 beta-lactamase Neisseria gonorrhoeae 4-18 1669013-1 1991 Production of TEM-1 beta-lactamase is the commonest cause of acquired resistance to amoxycillin and piperacillin in Escherichia coli, now occurring in c. 50% of isolates. Amoxicillin 84-95 TEM-1 beta-lactamase Escherichia coli 14-34 1701026-3 1990 We have developed radioimmunoassays employing ampicillin, amoxicillin and ticarcillin solid phases for the detection of penicillin-reactive IgE antibodies. Amoxicillin 58-69 immunoglobulin heavy constant epsilon Homo sapiens 140-143 2380766-1 1990 The in vitro sensitivity of amoxicillin alone and combined with clavulanic acid (ratio 4:1) as been studied by a spectrophotometric method utilizing crude extract of the following enzymes: TEM1, TEM2, SHV1, SHV2, TLE1, HMS1, LXA, P99, ENT208. Amoxicillin 28-39 CD248 molecule Homo sapiens 189-193 2121699-0 1990 Effect of low concentrations of clavulanic acid on the in-vitro activity of amoxycillin against beta-lactamase-producing Branhamella catarrhalis and Haemophilus influenzae. Amoxicillin 76-87 beta-lactamase TEM-1 Haemophilus influenzae 96-110 2121699-2 1990 In agar-dilution studies, 8 mg amoxycillin/l was required to inhibit 45 strains of beta-lactamase-producing B. catarrhalis, whereas all the strains were inhibited by 0.5 mg amoxycillin/l in the presence of 0.01 mg clavulanic acid/l. Amoxicillin 31-42 beta-lactamase TEM-1 Haemophilus influenzae 83-97 34837569-6 2022 RESULTS: We identified 9766 patients with ax-SpA (924 AS and 8842 nr-SpA) and 691,862 without SpA who had COVID-19. Amoxicillin 42-44 surfactant protein A1 Homo sapiens 45-48 34975778-5 2021 bla PRC-1 confers resistance to many beta-lactam antibiotics, including penicillins (penicillin G, amoxicillin, and amoxicillin-clavulanic acid) and cephalosporins (cefazolin, ceftriaxone, and cefotaxime). Amoxicillin 99-110 protein regulator of cytokinesis 1 Homo sapiens 4-9 34837569-7 2022 In the unmatched comparison, patients with ax-SpA had higher risk ratios (RR) for all outcomes. Amoxicillin 43-45 surfactant protein A1 Homo sapiens 46-49 34837569-9 2022 Only the risk of VTE was higher in ax-SpA patients (RR: 1.219 (1.037-1.433), p = 0.016). Amoxicillin 35-37 surfactant protein A1 Homo sapiens 38-41 34837569-10 2022 Amongst the ax-SpA group, males had worse outcomes in 9 out of the 11 domains except for VTE and cerebral infarction, while blacks had worse outcomes in all except for mortality and the need for renal replacement therapy. Amoxicillin 12-14 surfactant protein A1 Homo sapiens 15-18 34837569-13 2022 Ax-SpA patients who had been prescribed non-steroidal anti-inflammatory drugs in the 3 months prior to COVID-19 had poorer outcomes. Amoxicillin 0-2 surfactant protein A1 Homo sapiens 3-6 34837569-14 2022 CONCLUSION: In conclusion, COVID-19 outcomes were better in patients with ax-SpA as compared with PS matched controls except for increased risk for VTE. Amoxicillin 74-76 surfactant protein A1 Homo sapiens 77-80 34827284-6 2021 The amoxicillin, doxycycline, and co-amoxiclav use was significantly higher (5-10% difference in use) in PC4 areas with poultry farms present compared to areas without, even after adjusting for age, gender, smoking, socio-economic status, and goat farm presence. Amoxicillin 4-15 proprotein convertase subtilisin/kexin type 4 Homo sapiens 105-108 34542630-9 2021 An additional 500 mg amoxicillin every 4 h was sufficient to achieve the PTA for most relevant organisms but 2 hourly dosing was required for patients at risk of infective endocarditis. Amoxicillin 21-32 pre T cell antigen receptor alpha Homo sapiens 73-76 34699174-2 2021 The aim was to (1) assess the composition and localization of reaction products and their phase variation during the reaction in real time and directly in an aqueous environment and (2) investigate the reaction of AmOx and DAP with calcite and the transformations induced to the substrate with a time-resolved approach. Amoxicillin 214-218 death associated protein Homo sapiens 223-226 34158945-2 2021 A 76-year-old man was admitted to our hospital with slowness and confusion following a dental and gingival inflammation treated with oral amoxicillin 500 mg bid and ibuprofen 600 mg tid for 1 week. Amoxicillin 138-149 BH3 interacting domain death agonist Homo sapiens 157-160 34721043-0 2021 Influence of Cytochrome P450 2C19 Genotype on Helicobacter pylori Proton Pump Inhibitor-Amoxicillin-Clarithromycin Eradication Therapy: A Meta-Analysis. Amoxicillin 88-99 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 13-33 34575573-7 2021 The amoxicillin pretreatment (20 mg/kg/day, twice a day for 3 days) resulted in a significant decrease in the fecal recovery of CK, PPD, and PPT through the blockade of deglycosylation of ginsenosides after single oral administrations of RGE (2 g/kg) in mice. Amoxicillin 4-15 palmitoyl-protein thioesterase 1 Mus musculus 141-144 34502136-3 2021 By inducing amoxicillin resistance in Escherichia coli, followed by horizontal gene transfer experiments and sequencing, we show that the chromosomal beta-lactamase gene ampC is multiplied and results in an 8-13 kb contig. Amoxicillin 12-23 beta-lactamase Escherichia coli 170-174 34221533-5 2021 The method was validated in linear ranges of 2-28 microg mL-1, 2-35 microg mL-1, and 1-10 microg mL-1 for amoxicillin, dicloxacillin, and 6-aminopenicillanic acid, respectively. Amoxicillin 106-117 L1 cell adhesion molecule Mus musculus 97-101 34454095-0 2021 Targeting antibiotic tolerance in anaerobic biofilms associated with oral diseases: Human antimicrobial peptides LL-37 and lactoferricin enhance the antibiotic efficacy of amoxicillin, clindamycin and metronidazole. Amoxicillin 172-183 cathelicidin antimicrobial peptide Homo sapiens 113-118 34454095-0 2021 Targeting antibiotic tolerance in anaerobic biofilms associated with oral diseases: Human antimicrobial peptides LL-37 and lactoferricin enhance the antibiotic efficacy of amoxicillin, clindamycin and metronidazole. Amoxicillin 172-183 lactotransferrin Homo sapiens 123-136 34454095-4 2021 LL-37 and Lactoferricin enhanced the anti-biofilm effect of amoxicillin and clindamycin in facultative anaerobic biofilms. Amoxicillin 60-71 cathelicidin antimicrobial peptide Homo sapiens 0-5 34454095-4 2021 LL-37 and Lactoferricin enhanced the anti-biofilm effect of amoxicillin and clindamycin in facultative anaerobic biofilms. Amoxicillin 60-71 lactotransferrin Homo sapiens 10-23 34454095-7 2021 However, when combined with LL-37 or Lactoferricin, the reduction of obligate anaerobic biofilms was markedly enhanced for all antibiotics, even for amoxicillin and clindamycin. Amoxicillin 149-160 cathelicidin antimicrobial peptide Homo sapiens 28-33 34454095-7 2021 However, when combined with LL-37 or Lactoferricin, the reduction of obligate anaerobic biofilms was markedly enhanced for all antibiotics, even for amoxicillin and clindamycin. Amoxicillin 149-160 lactotransferrin Homo sapiens 37-50 34285790-1 2021 Aims: An antibiotic combination of amoxicillin, tetracycline and metronidazole (ATM) is effective for ulcerative colitis (UC), but this regimen is discontinued in some cases due to adverse events. Amoxicillin 35-46 ATM serine/threonine kinase Homo sapiens 80-83 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 CD8a molecule Homo sapiens 73-76 34297513-2 2021 METHODS: A retrospective analysis of 172 patients with ax-SpA was performed to assess the presence of active inflammatory and structural changes of the symphysis pubis on MRI scans, and their association with clinical factors and the SPARCC (Spondyloarthritis Research Consortium of Canada) scoring of the sacroiliac joint were evaluated. Amoxicillin 55-57 surfactant protein A1 Homo sapiens 58-61 34297513-7 2021 CONCLUSIONS: The MRI changes of the symphysis pubis were seen in 55.2% of the patients with ax-SpA and were associated with C-reactive protein, erythrocyte sedimentation rate, and symptom duration. Amoxicillin 92-94 surfactant protein A1 Homo sapiens 95-98 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 interleukin 6 Homo sapiens 78-82 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 CD8a molecule Homo sapiens 108-111 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 CD4 molecule Homo sapiens 129-132 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 tumor necrosis factor Homo sapiens 146-155 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 CD8a molecule Homo sapiens 173-176 35440370-6 2022 The addition of amoxicillin to clarithromycin resulted in an increase in CD8+ IL-6 (p = 0.010), decrease in CD8+ (p = 0.014) and CD4+ (p = 0.022) TNF-alpha, and decrease in CD8+ IFN-alpha (p = 0.038). Amoxicillin 16-27 interferon alpha 1 Homo sapiens 178-187 35259478-2 2022 We aimed to assess the prevalence of left ventricular (LV) systolic and diastolic dysfunction and valvular heart disease (VHD) by transthoracic echocardiography (TTE) in ax-SpA patients without history of CVD. Amoxicillin 170-172 surfactant protein A1 Homo sapiens 173-176 35432720-5 2022 On the other hand, the synergistic effect of AX and HFY06 enhanced the mRNA expressions of ZO-1, occludin, and claudin-1 in the small intestine of mice, increased the strength of the intestinal barrier, and optimized the composition of the intestinal microbiota. Amoxicillin 45-47 tight junction protein 1 Mus musculus 91-95 35432720-5 2022 On the other hand, the synergistic effect of AX and HFY06 enhanced the mRNA expressions of ZO-1, occludin, and claudin-1 in the small intestine of mice, increased the strength of the intestinal barrier, and optimized the composition of the intestinal microbiota. Amoxicillin 45-47 occludin Mus musculus 97-105 35432720-5 2022 On the other hand, the synergistic effect of AX and HFY06 enhanced the mRNA expressions of ZO-1, occludin, and claudin-1 in the small intestine of mice, increased the strength of the intestinal barrier, and optimized the composition of the intestinal microbiota. Amoxicillin 45-47 claudin 1 Mus musculus 111-120 35357862-2 2022 First, we used an AX +/BX-discrimination procedure to establish conditioned stimulus (CS) B as a learned safety signal that passed both summation and retardation tests of conditioned inhibition. Amoxicillin 18-20 citrate synthase Rattus norvegicus 86-88 35566244-6 2022 The adsorption performances of the novel polymeric adsorbents, PAB1, PAB2, and PAB3, were tested in the adsorption of three antibiotics, tetracycline, sulfamethoxazole, and amoxicillin, from aqueous solutions, by using extensive kinetic, equilibrium, and thermodynamic studies. Amoxicillin 173-184 poly(A) binding protein cytoplasmic 1 pseudogene 10 Homo sapiens 63-67 35566244-6 2022 The adsorption performances of the novel polymeric adsorbents, PAB1, PAB2, and PAB3, were tested in the adsorption of three antibiotics, tetracycline, sulfamethoxazole, and amoxicillin, from aqueous solutions, by using extensive kinetic, equilibrium, and thermodynamic studies. Amoxicillin 173-184 poly(A) binding protein nuclear 1 Homo sapiens 69-73 35401180-6 2022 Compared with the control group, the expression of P-glycoprotein (P-gp), CYP1A2, CYP2C9, CYP3A4, and nuclear receptor, PXR, were altered in the amoxicillin -treated groups. Amoxicillin 145-156 ATP binding cassette subfamily B member 1 Homo sapiens 51-65 35401180-6 2022 Compared with the control group, the expression of P-glycoprotein (P-gp), CYP1A2, CYP2C9, CYP3A4, and nuclear receptor, PXR, were altered in the amoxicillin -treated groups. Amoxicillin 145-156 ATP binding cassette subfamily B member 1 Homo sapiens 67-71 35401180-6 2022 Compared with the control group, the expression of P-glycoprotein (P-gp), CYP1A2, CYP2C9, CYP3A4, and nuclear receptor, PXR, were altered in the amoxicillin -treated groups. Amoxicillin 145-156 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 74-80 35401180-6 2022 Compared with the control group, the expression of P-glycoprotein (P-gp), CYP1A2, CYP2C9, CYP3A4, and nuclear receptor, PXR, were altered in the amoxicillin -treated groups. Amoxicillin 145-156 cytochrome P450 family 2 subfamily C member 9 Homo sapiens 82-88 35401180-6 2022 Compared with the control group, the expression of P-glycoprotein (P-gp), CYP1A2, CYP2C9, CYP3A4, and nuclear receptor, PXR, were altered in the amoxicillin -treated groups. Amoxicillin 145-156 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 90-96 35401180-6 2022 Compared with the control group, the expression of P-glycoprotein (P-gp), CYP1A2, CYP2C9, CYP3A4, and nuclear receptor, PXR, were altered in the amoxicillin -treated groups. Amoxicillin 145-156 nuclear receptor subfamily 1 group I member 2 Homo sapiens 120-123 35372582-7 2022 Antioxidant enzymes and oxidative stress parameters such as malondialdehyde concentrations (MDA) increased significantly while catalase, superoxide dismutase, reduced glutathione, and peroxidase reduced significantly in antibiotic amoxicillin-treated groups as compared to the untreated control group (P < 0.05). Amoxicillin 231-242 catalase Oryctolagus cuniculus 127-135 35259478-12 2022 LV diastolic TTE parameters are altered in ax-SpA. Amoxicillin 43-45 surfactant protein A1 Homo sapiens 46-49 35181690-6 2022 After treatment with killed Cnm-positive S. mutans, amoxicillin-treated bacteria still had collagen-binding ability, while lysozyme-treated bacteria lost this ability. Amoxicillin 52-63 collagen Bombyx mori 91-99 35174380-5 2022 The selected linear range for each analyte is as follows: 5-200 ng mL-1 for ampicillin; 0.1-200 ng mL-1 for amoxicillin and chloramphenicol; and 1-200 ng mL-1 for enrofloxacin and oxytetracycline, respectively. Amoxicillin 108-119 L1 cell adhesion molecule Mus musculus 99-103 35181690-9 2022 These results suggest that amoxicillin-killed Cnm-positive S. mutans strains maintain collagen-binding properties and pathogenicity in the silkworm model, and are possibly associated with pathogenicity in cardiovascular diseases. Amoxicillin 27-38 collagen Bombyx mori 86-94 35052944-6 2022 Results show that cefotaxime is the preferred inducer for CTX-M-15 and amoxicillin for TEM-1, whereas oxacillin for OXA-2. Amoxicillin 71-82 hypothetical protein Escherichia coli 87-92 35095517-0 2021 Amoxicillin Haptenation of alpha-Enolase is Modulated by Active Site Occupancy and Acetylation. Amoxicillin 0-11 enolase 1 Homo sapiens 27-40 35095517-6 2021 We previously identified the glycolytic enzyme alpha-enolase as a target for haptenation by amoxicillin, both in cells and in the extracellular milieu. Amoxicillin 92-103 enolase 1 Homo sapiens 47-60 35095517-7 2021 Here, we performed an in vitro study to analyze amoxicillin haptenation of alpha-enolase using gel-based and activity assays. Amoxicillin 48-59 enolase 1 Homo sapiens 75-88 35095517-8 2021 Moreover, the possible interplay or interference between amoxicillin haptenation and acetylation of alpha-enolase was studied in 1D- and 2D-gels that showed decreased haptenation and displacement of the haptenation signal to lower pI spots after chemical acetylation of the protein, respectively. Amoxicillin 57-68 enolase 1 Homo sapiens 100-113 35095517-9 2021 In addition, the peptide containing lysine 239 was identified by mass spectrometry as the amoxicillin target sequence on alpha-enolase, thus suggesting a selective haptenation under our conditions. Amoxicillin 90-101 enolase 1 Homo sapiens 121-134 35095517-10 2021 The putative amoxicillin binding site and the surrounding interactions were investigated using the alpha-enolase crystal structure and molecular docking. Amoxicillin 13-24 enolase 1 Homo sapiens 99-112 34988956-5 2022 RESULTS: We found that 13 (29.5%) of 42 patients with ax-SpA had coccydynia. Amoxicillin 54-56 surfactant protein A1 Homo sapiens 57-60 34988956-9 2022 CONCLUSION: Our study supports the increased prevalence of coccydynia in patients with ax-SpA. Amoxicillin 87-89 surfactant protein A1 Homo sapiens 90-93