PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 19666465-1 2009 Tetrahyrobiopterin (BH4) is a required cofactor for the synthesis of nitric oxide by endothelial nitric-oxide synthase (eNOS), and BH4 bioavailability within the endothelium is a critical factor in regulating the balance between NO and superoxide production by eNOS (eNOS coupling). tetrahyrobiopterin 0-18 nitric oxide synthase 3 Homo sapiens 85-118