PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9402952-0	1997	Pig hepatocytes as an in vitro model to study the regulation of human CYP3A4: prediction of drug-drug interactions with 17 alpha-ethynylestradiol.	alpha-ethynylestradiol	123-145	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	70-76
19931644-1	2010	We found that temperature and photoperiod significantly influence the transcription of the estrogen-responsive genes, vitellogenin1 (Vtg1), vitellogenin2 (Vtg2), estrogen receptor-alpha (ER alpha) and estrogen receptor-beta (ER beta), after a 21-day exposure to environmentally relevant concentrations of 17 alpha-ethynylestradiol (EE2), nonylphenol (NP) and EE2 plus NP (EE2+NP).	alpha-ethynylestradiol	308-330	vitellogenin 1	Danio rerio	118-131
7492675-4	1995	Plasma PAF-AH activity in adult female rats (14 wk of age) treated with 17 alpha-ethynylestradiol (100 micrograms/kg, 5 days) was decreased by 70%.	alpha-ethynylestradiol	75-97	PCNA clamp associated factor	Rattus norvegicus	7-10
8346925-11	1993	Plasma PAF-AH activity was increased significantly by the administration of dexamethasone (P < 0.001) or medroxyprogesterone (P < 0.001), and decreased by 17 alpha-ethynylestradiol (P < 0.001), as previously described.	alpha-ethynylestradiol	164-186	PCNA clamp associated factor	Rattus norvegicus	7-10
8233731-8	1993	In contrast, lower amounts of PAF were sufficient to cause bowel necrosis and hemoconcentration when decreased activities of plasma PAF-AH were induced by 17 alpha-ethynylestradiol or 4-aminopyrazolopyrimidine administration.	alpha-ethynylestradiol	158-180	PCNA clamp associated factor	Rattus norvegicus	30-33
8233731-8	1993	In contrast, lower amounts of PAF were sufficient to cause bowel necrosis and hemoconcentration when decreased activities of plasma PAF-AH were induced by 17 alpha-ethynylestradiol or 4-aminopyrazolopyrimidine administration.	alpha-ethynylestradiol	158-180	PCNA clamp associated factor	Rattus norvegicus	132-135