PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
23124878-10	2013	CONCLUSION: beta-catenin binds to the PTHR-1 C-tail and switches the downstream signaling pathway from G(alphas)/cAMP to G(alphaq)/Ca(2+), which is a possible mechanism by which chondrocyte hypertrophy may be regulated through the PTH/PTHrP signal independent of the canonical Wnt pathway.	methylphenyl carbinol	105-111	catenin beta 1	Homo sapiens	12-24
24992599-2	2014	In the present study, we observed that miR-122 over-expression in HCC cell lines Sk-hep-1 and Bel-7402 triggered the mesenchymal-epithelial transition (MET), as demonstrated by epithelial-like morphological changes, up-regulated epithelial proteins (E-cadherin, ZO-1, alpha-catenin, occludin, BVES, and MST4), and down-regulated mesenchymal proteins (vimentin and fibronectin).	methylphenyl carbinol	268-273	microRNA 122	Homo sapiens	39-46
24392725-2	2014	This new HOF exhibits not only a permanent porosity with the BET of 237.6 m(2) g(-1) but also, more importantly, a highly enantioselective separation of chiral secondary alcohols with ee value up to 92% for 1-phenylethanol.	methylphenyl carbinol	207-222	delta/notch like EGF repeat containing	Homo sapiens	61-64
24078149-4	2014	The second couples the CV2025 omega-TAm with alcohol dehydrogenase and glucose dehydrogenase for removal of the acetophenone (AP) by-product by in situ conversion to (R)-1-phenylethanol.	methylphenyl carbinol	166-185	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	Homo sapiens	71-92
23124878-10	2013	CONCLUSION: beta-catenin binds to the PTHR-1 C-tail and switches the downstream signaling pathway from G(alphas)/cAMP to G(alphaq)/Ca(2+), which is a possible mechanism by which chondrocyte hypertrophy may be regulated through the PTH/PTHrP signal independent of the canonical Wnt pathway.	methylphenyl carbinol	105-111	parathyroid hormone 1 receptor	Homo sapiens	38-44
23124878-10	2013	CONCLUSION: beta-catenin binds to the PTHR-1 C-tail and switches the downstream signaling pathway from G(alphas)/cAMP to G(alphaq)/Ca(2+), which is a possible mechanism by which chondrocyte hypertrophy may be regulated through the PTH/PTHrP signal independent of the canonical Wnt pathway.	methylphenyl carbinol	105-111	parathyroid hormone like hormone	Homo sapiens	235-240
22694121-4	2012	Herein, we report the design of a superactive d-peptide antagonist of MDM2, termed (D)PMI-delta, of which the binding affinity for ((25-109))MDM2 has been improved over (D)PMI-alpha by 3 orders of magnitude (K(d) = 220 pM).	methylphenyl carbinol	176-181	MDM2 proto-oncogene	Homo sapiens	70-74
22038845-8	2012	We propose that alpha-TEA is a promising drug efficient against breast cancer, as documented by its effect on experimental HER2-positive breast carcinomas that present a considerable problem in cancer management.	methylphenyl carbinol	16-22	erb-b2 receptor tyrosine kinase 2	Homo sapiens	123-127
21675799-2	2011	The turnover frequency of the hydrogenation of acetophenone reaches about 35,000 min(-1) in the best case, affording 1-phenylethanol in >99% ee.	methylphenyl carbinol	117-132	CD59 molecule (CD59 blood group)	Homo sapiens	81-87
22349417-4	2012	Modulation of cigarette smoke (CS) induced oxidative stress and its consequent cellular changes have also been reported to be effected by synthetic molecules, such as spin traps (alpha-phenyl-N-tert-butyl nitrone), catalytic antioxidants (superoxide dismutase [ECSOD] mimetics), porphyrins, and lipid peroxidation and protein carbonylation blockers/inhibitors (edaravone and lazaroids/tirilazad).	methylphenyl carbinol	179-184	superoxide dismutase 3	Homo sapiens	261-266
21917987-4	2012	The alpha6*-preferring alpha-Ctx MII mutant analogs, alpha-Ctx MII[H9A,L15A] and alpha-Ctx MII[S4A,E11A,L15A], blocked nAChR currents with an IC(50) of 217.8 and 33 nM, respectively.	methylphenyl carbinol	4-9	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	119-124
22469663-7	2012	Each component of beta-catenin/APC/alpha-catenin complex co-exists in other protein complexes, thus use of a selective antibody for affinity proteomics has allowed us to go beyond the generation of a list of potential beta-catenin-interacting proteins, and define when and where a specific complex forms.	methylphenyl carbinol	35-40	catenin beta 1	Homo sapiens	18-30
22304775-16	2012	In PTH and 1, 25(OH)(2);D(3); group,  the cells of alpha-SMA positive expressed were significantly less than those in PTH group (P<0.05).	methylphenyl carbinol	51-56	parathyroid hormone	Homo sapiens	3-6
22304775-16	2012	In PTH and 1, 25(OH)(2);D(3); group,  the cells of alpha-SMA positive expressed were significantly less than those in PTH group (P<0.05).	methylphenyl carbinol	51-56	WD repeat and HMG-box DNA binding protein 1	Homo sapiens	7-12
21489790-6	2011	Herein, we describe the synthesis of a small set of alpha-substituted phosphonate analogs of S32826, and we show that shortening the chain and adding alpha-halo or alpha-hydroxy substituents increased solubility; however, ATX inhibition was reduced by most substitutions.	methylphenyl carbinol	52-57	ectonucleotide pyrophosphatase/phosphodiesterase 2	Homo sapiens	222-225
20930172-3	2010	Pretreatment with low concentrations of alpha-thrombin before the addition of tissue factor and Ca(2+) accelerated the rate of thrombin generation (time to reach half of peak thrombin was reduced by [mean +- SD] 42.0 +- 2.2%; P<0.05) but had no effect on the amount of peak thrombin generated.	methylphenyl carbinol	40-46	coagulation factor II, thrombin	Homo sapiens	127-135
20930172-3	2010	Pretreatment with low concentrations of alpha-thrombin before the addition of tissue factor and Ca(2+) accelerated the rate of thrombin generation (time to reach half of peak thrombin was reduced by [mean +- SD] 42.0 +- 2.2%; P<0.05) but had no effect on the amount of peak thrombin generated.	methylphenyl carbinol	40-46	coagulation factor II, thrombin	Homo sapiens	127-135
20930172-3	2010	Pretreatment with low concentrations of alpha-thrombin before the addition of tissue factor and Ca(2+) accelerated the rate of thrombin generation (time to reach half of peak thrombin was reduced by [mean +- SD] 42.0 +- 2.2%; P<0.05) but had no effect on the amount of peak thrombin generated.	methylphenyl carbinol	40-46	coagulation factor II, thrombin	Homo sapiens	127-135
20663922-7	2010	To gain further insight into the membrane-proximal signalling, AGS cells were stably transfected with E-cadherin-alpha-catenin fusions.	methylphenyl carbinol	113-118	cadherin 1	Homo sapiens	102-112
20361761-2	2010	Here we evaluated the characteristics of insulin and deoxycholate-based synthetic N(alpha)-deoxycholyl-L-lysyl-methylester (DCK) complex, and diabetes correction in pancreatectomized canines after oral administration.	methylphenyl carbinol	84-89	deoxycytidine kinase	Canis lupus familiaris	124-127
19171887-9	2009	Thus, Mincle may recognize specific geometry of alpha-mannosyl residues on Malassezia species and use this to distinguish them from other fungi.	methylphenyl carbinol	48-53	C-type lectin domain family 4, member e	Mus musculus	6-12
20346653-3	2010	Based on the structural similarities between the initial hit and a well-known imidazole pyrimidine series of p38alpha inhibitors, potencies within the newly discovered series were quickly improved by installation of an (S)-alpha-methylbenzyl moiety at the 2-position of the pyridine ring.	methylphenyl carbinol	219-241	mitogen-activated protein kinase 14	Homo sapiens	109-117
20224651-2	2010	In this study, we investigated the effects of alpha-TEA on the expression of epidermal growth factor receptor (EGFR) family members, ErbB1, 2 and 3, and the role of ErbB 2 and 3 in alpha-TEA-induced apoptosis and suppression of Akt, FLIP and survivin in the cisplatin-sensitive (A2780S) and -resistant (A2780/CP70R) human ovarian cancer cell lines.	methylphenyl carbinol	46-51	epidermal growth factor receptor	Homo sapiens	77-109
19359588-3	2009	Forced expression of mutant IDH1 in cultured cells reduces formation of the enzyme product, alpha-ketoglutarate (alpha-KG), and increases the levels of hypoxia-inducible factor subunit HIF-1alpha, a transcription factor that facilitates tumor growth when oxygen is low and whose stability is regulated by alpha-KG.	methylphenyl carbinol	92-97	isocitrate dehydrogenase (NADP(+)) 1	Homo sapiens	28-32
20224651-2	2010	In this study, we investigated the effects of alpha-TEA on the expression of epidermal growth factor receptor (EGFR) family members, ErbB1, 2 and 3, and the role of ErbB 2 and 3 in alpha-TEA-induced apoptosis and suppression of Akt, FLIP and survivin in the cisplatin-sensitive (A2780S) and -resistant (A2780/CP70R) human ovarian cancer cell lines.	methylphenyl carbinol	46-51	epidermal growth factor receptor	Homo sapiens	111-115
19143512-3	2009	Furthermore, the chiral recognition of the two enantiomers of alpha-amino carboxylates was also studied, and R-1 displayed a remarkable binding ability for the t-Boc alanine anion with an interesting enantioselectivity (K(L)/K(D) = 4.5).	methylphenyl carbinol	62-67	CD1b molecule	Homo sapiens	109-112
18777014-4	2009	Wheat germ lipase had a high activity and enantioselectivity only in n-hexane with a high initial water activity (alpha(w) = 0.97), especially with 1-phenylethanol (C 32%, E > 200).	methylphenyl carbinol	148-163	probable feruloyl esterase A	Triticum aestivum	11-17
17825301-4	2007	We conclude that alpha-TOS disrupts angiogenesis mediated by MM cells by inhibiting FGF2 paracrine signalling.	methylphenyl carbinol	17-22	fibroblast growth factor 2	Homo sapiens	84-88
18566211-9	2008	Further, Src-mediated tyrosine phosphorylation of beta-catenin is a major mechanism for decreased beta-catenin interaction with E-cadherin in alpha-catenin-null cells.	methylphenyl carbinol	142-147	SRC proto-oncogene, non-receptor tyrosine kinase	Homo sapiens	9-12
18566211-9	2008	Further, Src-mediated tyrosine phosphorylation of beta-catenin is a major mechanism for decreased beta-catenin interaction with E-cadherin in alpha-catenin-null cells.	methylphenyl carbinol	142-147	catenin beta 1	Homo sapiens	50-62
18566211-9	2008	Further, Src-mediated tyrosine phosphorylation of beta-catenin is a major mechanism for decreased beta-catenin interaction with E-cadherin in alpha-catenin-null cells.	methylphenyl carbinol	142-147	catenin beta 1	Homo sapiens	98-110
18566211-9	2008	Further, Src-mediated tyrosine phosphorylation of beta-catenin is a major mechanism for decreased beta-catenin interaction with E-cadherin in alpha-catenin-null cells.	methylphenyl carbinol	142-147	cadherin 1	Homo sapiens	128-138
18553919-9	2008	In conclusion, alpha-acarviosinyl-(1-->9)-3-alpha-D-glucopyranosylpropen is a novel alpha-glucosidase-selective inhibitor with 10-fold enhanced selectivity toward alpha-glucosidase over alpha-amylase relative to acarbose, and it could be applied as a potent hypoglycemic agent.	methylphenyl carbinol	15-20	sucrase-isomaltase	Homo sapiens	87-104
18553919-9	2008	In conclusion, alpha-acarviosinyl-(1-->9)-3-alpha-D-glucopyranosylpropen is a novel alpha-glucosidase-selective inhibitor with 10-fold enhanced selectivity toward alpha-glucosidase over alpha-amylase relative to acarbose, and it could be applied as a potent hypoglycemic agent.	methylphenyl carbinol	15-20	sucrase-isomaltase	Homo sapiens	166-183
18397317-4	2008	The human glucokinase-alpha-D-glucose association (K(d) = 4.8 +/- 0.1 mm at 25 degrees C) is driven by a favourable entropy change (DeltaS = 150 +/- 10 J.mol(-1).K(-1)).	methylphenyl carbinol	22-27	glucokinase	Homo sapiens	10-21
18083578-6	2008	Whereas, (alphaS, betaS)- and (alphaS, betaR)-2-{4-[2-(2-hydroxy-2-phenylethylamino)ethyl]phenoxy}propanoic acid behaved as beta(3)-adrenoceptor inverse agonists.	methylphenyl carbinol	10-16	adrenoceptor beta 3	Homo sapiens	124-144
17516611-6	2007	Racemization at room temperature of a 1:1 mixture of (S)-1-phenylethanol and (S)-1-phenyl-[D4]-ethanol gave only rac-1-phenylethanol, and rac-1-phenyl-[D4]-ethanol, providing strong support for a mechanism in which the substrate stays coordinated to the metal center throughout the racemization, and does not leave the coordination sphere.	methylphenyl carbinol	53-72	Rac family small GTPase 1	Homo sapiens	113-118
17559170-5	2007	Presumably, the recognition of the alpha-mannosyl residue of the alpha-ManCer analogues by the invariant TCR is individually modulated, depending on the altered interaction with the groove of the antigen-presenting MR1.	methylphenyl carbinol	35-40	major histocompatibility complex, class I-related	Mus musculus	215-218
17004277-3	2007	Combined with an immobilized lipase from Candida antarctica, the dynamic kinetic resolution of 1-phenylethanol to the (R)-phenylethylester can be achieved with high yield and selectivity.	methylphenyl carbinol	95-110	PAN0_003d1715	Moesziomyces antarcticus	29-35
17516611-6	2007	Racemization at room temperature of a 1:1 mixture of (S)-1-phenylethanol and (S)-1-phenyl-[D4]-ethanol gave only rac-1-phenylethanol, and rac-1-phenyl-[D4]-ethanol, providing strong support for a mechanism in which the substrate stays coordinated to the metal center throughout the racemization, and does not leave the coordination sphere.	methylphenyl carbinol	53-72	Rac family small GTPase 1	Homo sapiens	138-143
17441044-2	2006	[Ru(OSO2CF3){(S,S)-TsNCH(C6H5)CH(C6H5)NH2}(eta(6)-p-cymene)] catalyzes the asymmetric hydrogenation of acetophenone in methanol to afford (S)-1-phenylethanol with 96% ee in 100% yield.	methylphenyl carbinol	138-157	endothelin receptor type A	Homo sapiens	43-46
17091155-1	2006	Cubic nanoparticles of alpha-AlF(3) containing 864 and 2048 atoms were investigated by using molecular dynamics simulations.	methylphenyl carbinol	23-28	afamin	Homo sapiens	29-32
17107071-2	2006	The key conceptual breakthrough is the use of sec-phenethyl alcohol at relatively low concentrations as the sacrificial alcohol to undergo oxidation and provide the proposed Pd-H intermediate.	methylphenyl carbinol	46-67	pyruvate dehydrogenase phosphatase catalytic subunit 1	Homo sapiens	174-178
16829221-7	2006	The extent of aspartic acid isomerization of type I collagen C telopeptide (CTX) was evaluated by ELISA of native (alpha CTX) and isomerized (beta CTX) forms.	methylphenyl carbinol	115-120	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	45-80
16829221-7	2006	The extent of aspartic acid isomerization of type I collagen C telopeptide (CTX) was evaluated by ELISA of native (alpha CTX) and isomerized (beta CTX) forms.	methylphenyl carbinol	115-120	cytochrome P450 family 27 subfamily A member 1	Homo sapiens	76-79
16226717-1	2005	We report here the unexpected finding that recombinant or hepatic microsomal NADPH-cytochrome P450 reductase catalyzes the oxidative deformylation of a model xenobiotic aldehyde, 2-phenylpropionaldehyde, to the n-1 alcohol, 1-phenylethanol, in the absence of cytochrome P450.	methylphenyl carbinol	224-239	cytochrome p450 oxidoreductase	Homo sapiens	77-108
16818789-8	2006	Purified Galectin-3 is able to bind directly to Gal-alpha(1,3)Gal-beta(1,4)GlcNAc-R. Galectin-3 can also be affinity isolated from monocytes (and not lymphocytes) using an Gal-alpha(1,3)Gal-beta(1,4)GlcNAc-R-biotin/streptavidin-bead pull-down system.	methylphenyl carbinol	52-58	galectin 3	Homo sapiens	9-19
16818789-8	2006	Purified Galectin-3 is able to bind directly to Gal-alpha(1,3)Gal-beta(1,4)GlcNAc-R. Galectin-3 can also be affinity isolated from monocytes (and not lymphocytes) using an Gal-alpha(1,3)Gal-beta(1,4)GlcNAc-R-biotin/streptavidin-bead pull-down system.	methylphenyl carbinol	52-58	galectin 3	Homo sapiens	85-95
14967154-5	2004	METHODS: Excretion of alpha-KG was measured by gas-chromatography/mass spectrometry (GC/MS) in eight patients with an activating GLUD1 mutation and 90 controls.	methylphenyl carbinol	22-28	glutamate dehydrogenase 1	Homo sapiens	129-134
16334164-10	2005	Low expressions of alpha- (p = 0.06) and beta-catenin (p = 0.05) were related to shortened PSA RFS.	methylphenyl carbinol	19-25	aminopeptidase puromycin sensitive	Homo sapiens	91-94
16117535-4	2005	We evaluated several types of helical foldamer, built entirely from beta-amino acid residues or from mixtures of alpha- and beta-amino acid residues, and ultimately identified foldamers in the latter class that bind very tightly to Bcl-xL.	methylphenyl carbinol	113-119	BCL2 like 1	Homo sapiens	232-238
15280361-6	2004	On the basis of the tridimensional structure of Exg1, we propose that Xaa influences the orientation of the inner core making it accessible to mannan polymerase I in the appropriate position for the addition of alpha-1,6-mannoses.	methylphenyl carbinol	211-216	glucan 1,3-beta-glucosidase	Saccharomyces cerevisiae S288C	48-52
15634943-6	2005	Moreover, inhibition of gamma-GT with acivicin increases the concentration of GSH and N-acetylcysteine conjugates of N-methyl-alpha-MeDA in brain dialysate, and there is a direct correlation between the concentrations of metabolites in dialysate and the extent of neurotoxicity, measured by decreases in serotonin (5-HT) and 5-hydroxyindole acetic (5-HIAA) levels.	methylphenyl carbinol	126-131	gamma-glutamyltransferase 1	Rattus norvegicus	24-32
14629155-7	2003	The reaction of 1-phenylethanol (4a) in the presence of Sc(OTf)3 in nitromethane gave an equilibrium mixture of 4a and bis(1-phenylethyl) ether (54).	methylphenyl carbinol	16-31	POU class 5 homeobox 1	Homo sapiens	56-64
12198706-5	2002	The aim of this study was to perform a systematic characterization of DQ2-restricted T-cell epitopes in alpha- and gamma-gliadins.	methylphenyl carbinol	104-109	torsin family 1 member A	Homo sapiens	70-73
13679071-1	2003	Antithrombin (AT) circulates in two isoforms, alpha- (90-95%) and beta-AT (5-10%).	methylphenyl carbinol	46-52	serpin family C member 1	Homo sapiens	0-12
12882012-0	2003	Simultaneous synthesis of enantiomerically pure (R)-1-phenylethanol and (R)-alpha-methylbenzylamine from racemic alpha-methylbenzylamine using omega-transaminase/alcohol dehydrogenase/glucose dehydrogenase coupling reaction.	methylphenyl carbinol	48-67	aldo-keto reductase family 1 member A1	Homo sapiens	162-183
12727803-12	2003	Stratification by GSTM1 genotype, however, showed a significant negative association between DNA adduct levels and plasma levels of alpha- (P = 0.02) and beta-carotene (P = 0.02) in subjects with the GSTM1 null genotype.	methylphenyl carbinol	132-138	glutathione S-transferase mu 1	Homo sapiens	18-23
12727803-12	2003	Stratification by GSTM1 genotype, however, showed a significant negative association between DNA adduct levels and plasma levels of alpha- (P = 0.02) and beta-carotene (P = 0.02) in subjects with the GSTM1 null genotype.	methylphenyl carbinol	132-138	glutathione S-transferase mu 1	Homo sapiens	200-205
12899840-1	2003	Alpha-tocopherol transfer protein (alpha-TTP) is a liver protein responsible for the selective retention of alpha-tocopherol from dietary vitamin E, which is a mixture of alpha, beta, gamma, and delta-tocopherols and the corresponding tocotrienols.	methylphenyl carbinol	171-177	alpha tocopherol transfer protein	Homo sapiens	0-33
12899840-1	2003	Alpha-tocopherol transfer protein (alpha-TTP) is a liver protein responsible for the selective retention of alpha-tocopherol from dietary vitamin E, which is a mixture of alpha, beta, gamma, and delta-tocopherols and the corresponding tocotrienols.	methylphenyl carbinol	171-177	alpha tocopherol transfer protein	Homo sapiens	35-44
12882012-1	2003	A simultaneous synthesis of (R)-1-phenylethanol and (R)-alpha-methylbenzylamine from racemic alpha-methylbenzylamine was achieved using an omega-transaminase, alcohol dehydrogenase, and glucose dehydrogenase in a coupled reaction.	methylphenyl carbinol	28-47	aldo-keto reductase family 1 member A1	Homo sapiens	159-180
12882012-1	2003	A simultaneous synthesis of (R)-1-phenylethanol and (R)-alpha-methylbenzylamine from racemic alpha-methylbenzylamine was achieved using an omega-transaminase, alcohol dehydrogenase, and glucose dehydrogenase in a coupled reaction.	methylphenyl carbinol	28-47	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	Homo sapiens	186-207
11902289-11	2002	Alpha-ketoisocaproic turnover positively correlated (R = 0.7, p = .03) with duration of pediatric intensive care unit admission and with prealbumin and RBP serum levels (R = 0.9, p = .001).	methylphenyl carbinol	0-5	retinol binding protein 4	Homo sapiens	152-155
11802709-3	2002	The cooperative binding of two Ca(2+) ions to the C2 domain of cytosolic phospholipase A(2) (cPLA(2)-alpha) induces docking to phosphatidylcholine (PC) membranes.	methylphenyl carbinol	101-106	phospholipase A2 group IVA	Homo sapiens	63-91
11591738-7	2001	To further characterize CD1d-restricted NKT cells, we generated an alpha-GalCer-responsive NKT cell line from thymocytes.	methylphenyl carbinol	67-73	CD1d molecule	Homo sapiens	24-28
11808555-4	2002	The ratio of alpha:gamma HCH was 5.0 and 3.4 for the Bering and Chukchi sea, respectively, which indicated the different pesticide composition in these two regions.	methylphenyl carbinol	13-18	S13 erythroblastosis (avian) oncogene homolog	Homo sapiens	72-75
11447235-11	2001	Minimal 15-hydroxyprostaglandin dehydrogenase oxidation of PGF(2 alpha)-G was observed.	methylphenyl carbinol	65-71	carbonyl reductase 1	Homo sapiens	8-45
11224564-5	2001	Human BVR-B is a monomer displaying an alpha/beta dinucleotide binding fold.	methylphenyl carbinol	39-44	biliverdin reductase B	Homo sapiens	6-11
11750640-0	2001	The alpha-Gal analog GAS914 ameliorates delayed rejection of hDAF transgenic pig-to-baboon renal xenografts.	methylphenyl carbinol	4-9	CD55 molecule (Cromer blood group)	Homo sapiens	61-65
11501068-5	2000	DNA fragments of about 1.0 kb in length were obtained by RT-PCR from RNA isolated from these cells and were detected by FUT2-specific [alpha-32P]dATP labeled DNA probes.	methylphenyl carbinol	135-140	fucosyltransferase 2	Homo sapiens	120-124
10906071-8	2000	In addition, we recently identified the regulatory subunit isoforms RI alpha, RII alpha, and an A-kinase anchoring protein, hAKAP220 in this region in sperm that could target C alpha-s.	methylphenyl carbinol	177-184	A-kinase anchoring protein 11	Homo sapiens	124-132
11012721-6	2000	Therefore, if Mdr65A mutants contribute to the difference between alpha-amanitin-resistant and alpha-amanitin-sensitive third chromosome lines, the underlying cause is a gene regulatory mutation.	methylphenyl carbinol	66-71	Multi drug resistance 65	Drosophila melanogaster	14-20
10551876-3	1999	We demonstrated the capacity of alpha/beta-GMR to bind GM-CSF with low affinity and to induce GM-CSF-dependent activation of tyrosine kinase activity and proliferation in transfected Ba/F3 cells.	methylphenyl carbinol	32-38	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	94-100
10551876-3	1999	We demonstrated the capacity of alpha/beta-GMR to bind GM-CSF with low affinity and to induce GM-CSF-dependent activation of tyrosine kinase activity and proliferation in transfected Ba/F3 cells.	methylphenyl carbinol	32-38	colony stimulating factor 2 (granulocyte-macrophage)	Mus musculus	55-61
10482506-2	1999	strain EB1 was recently shown to be initiated by dehydrogenation of ethylbenzene to 1-phenylethanol.	methylphenyl carbinol	84-99	microtubule associated protein RP/EB family member 1	Homo sapiens	7-10
10482506-12	1999	strain EB1 cells that were grown anaerobically on ethylbenzene, 1-phenylethanol, and acetophenone, but these activities were absent in benzoate-grown cells.	methylphenyl carbinol	64-79	microtubule associated protein RP/EB family member 1	Homo sapiens	7-10
10941798-5	1999	These results suggest that strain EbN1 degrades ethylbenzene via 1-phenylethanol and acetophenone as intermediates, and that acetophenone is subsequently carboxylated.	methylphenyl carbinol	65-80	potassium voltage-gated channel subfamily Q member 2	Homo sapiens	34-38
10222230-2	1999	Demethylation activities of either truncated 2B4 with N-methylaniline, N,N-dimethylaniline, and d-benzphetamine were lower than those of liver microsomal 2B4, whereas the rate of 1-phenylethanol oxidation to acetophenone catalyzed by liver microsomal and truncated 2B4 enzymes was nearly the same.	methylphenyl carbinol	179-194	CD244 molecule	Homo sapiens	45-48
12552849-0	1999	[The resolution of racemic sec-phenethyl alcohol on cellulose tribenzoate-based CSP: influence of different alcohols in the mobile phase].	methylphenyl carbinol	27-48	DnaJ heat shock protein family (Hsp40) member C5	Homo sapiens	80-83
9782163-3	1998	Receptor pharmacology with bath-applied antagonists indicated that oscillatory network activity depended crucially on the participation of cholinergic muscarinic, (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/kainate and GABAA receptors.	methylphenyl carbinol	163-172	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	243-248
9625525-1	1998	IP-10 is a member of the alpha or cysteine-X amino acid-cysteine (CXC) chemokine family of chemotactic cytokines.	methylphenyl carbinol	25-30	chemokine (C-X-C motif) ligand 10	Mus musculus	0-5
9281613-12	1997	Taken together, the results suggest that the adenosine and alpha-phosphate moieties of ATP bind to critical residues in TM3 and TM7 on the exofacial side of the human P2Y1 receptor.	methylphenyl carbinol	59-64	tropomyosin 3	Homo sapiens	120-123
9281613-12	1997	Taken together, the results suggest that the adenosine and alpha-phosphate moieties of ATP bind to critical residues in TM3 and TM7 on the exofacial side of the human P2Y1 receptor.	methylphenyl carbinol	59-64	purinergic receptor P2Y1	Homo sapiens	167-180
7989376-10	1994	Addition of both the short and long form of recombinant Gs alpha (rGs alpha-s and rGs alpha-L) restored guanine nucleotide-dependent adenylyl cyclase activity to oGTP-treated platelet membranes with rGs alpha-L being approximately 3-10-fold more potent than rGs alpha-s.	methylphenyl carbinol	70-77	GNAS complex locus	Homo sapiens	56-64
8940106-6	1996	Gsalpha was specifically immunoprecipitated from A431 cells using the anti-alphas antiserum AS 348.	methylphenyl carbinol	75-81	GNAS complex locus	Homo sapiens	0-7
8578546-0	1995	Effects of antithrombin III (AT III) and Trp49-modified AT III on plasma level of 6-keto-PGF1 alpha in rats.	methylphenyl carbinol	94-99	serpin family C member 1	Rattus norvegicus	56-62
8578546-1	1995	We evaluated the effect of antithrombin III (AT III) on the plasma level of 6-keto-PGF1 alpha in rats to determine whether AT III may promote the release of prostacyclin (PGl2) from endothelial cells in vivo.	methylphenyl carbinol	88-93	serpin family C member 1	Rattus norvegicus	45-51
9300141-1	1997	Two photoaffinity-labeling probes for retinoic acid receptor (RAR) alpha, 4-[(3-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)carboxamido]ben zoic acid (3DIAM) and its para-isomer (4DIAM), were designed and synthesized.	methylphenyl carbinol	67-72	retinoic acid receptor alpha	Homo sapiens	62-65
8824622-3	1996	In anaerobic suspensions of strain EB1 cells metabolizing ethylbenzene, the transient formation and consumption of 1-phenylethanol, acetophenone, and an as yet unidentified compound were observed.	methylphenyl carbinol	115-130	microtubule associated protein RP/EB family member 1	Homo sapiens	35-38
8787021-1	1996	The photochemistry of alpha-terthienyl (alpha-T) has been examined in bovine serum albumin (BSA).	methylphenyl carbinol	22-28	albumin	Homo sapiens	77-90
7578231-9	1995	1H-NMR spectroscopy of the HMW complex formed between alpha-crystallin and gamma-crystallin indicates that the short C-terminal extension of alpha B-crystallin, but not that of alpha A-crystallin, has lost its flexibility in the complex implying that the former is involved in interactions with the unfolded gamma-crystallin molecule, possibly electrostatically via its two C-terminal lysine residues.	methylphenyl carbinol	54-60	crystallin alpha B	Bos taurus	141-159
7723732-1	1995	Neuronal acetylcholine receptors (AChRs) that bind alpha-bungarotoxin (alpha Bgt) (alpha Bgt-AChRs) have previously been found to contain at least one of the alpha 7-alpha 9 gene products.	methylphenyl carbinol	51-57	gap junction protein, alpha 10, 62kDa	Gallus gallus	158-173
7910716-7	1994	Cholinesterase activities (mean nadir +/- standard deviation, 42.6 +/- 13.7 kU/L), and serum cholesterol levels (4.4 +/- 0.9 mmol/L) decreased upon SC rIL-2/rIFN-alpha combination therapy.	methylphenyl carbinol	162-167	interleukin 2	Rattus norvegicus	151-156
1434539-9	1992	alpha-Thrombin enhanced the initial rate of IL-1, TNF-alpha and f-norLeu-Leu-Phe induced PMNL transendothelial migration in an additive or supradditive manner (e.g., with IL-1 alpha+alpha-thrombin, migration was 58% greater than additive at 15 to 30 minutes, p < 0.001).	methylphenyl carbinol	0-5	coagulation factor II, thrombin	Homo sapiens	6-14
8220881-2	1993	In Fura-2 preloaded human platelets, the increase in cytosolic calcium induced by alpha-thrombin was reduced by some L- and D-arginine ester compounds the IC50 (microM) values of which were 7.4 for TAEE, 56.9 for BAEE, 77.6 for TAME, 560 for T(d)AME, 656.3 for L-ArgOMe and 2206.7 for D-ArgOMe.	methylphenyl carbinol	82-87	coagulation factor II, thrombin	Homo sapiens	88-96
8309554-1	1993	The distribution and expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-selective glutamate receptor subunits (GluR1-4) were studied in cultured hippocampal neurons using antibodies generated against peptides corresponding to the C-termini of GluR1, GluR2/3 and GluR4, and with a set of oligonucleotide probes designed complementary to specific pan, flip and flop GluR1-4 messenger RNA sequences.	methylphenyl carbinol	35-40	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	127-134
8309554-1	1993	The distribution and expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate-selective glutamate receptor subunits (GluR1-4) were studied in cultured hippocampal neurons using antibodies generated against peptides corresponding to the C-termini of GluR1, GluR2/3 and GluR4, and with a set of oligonucleotide probes designed complementary to specific pan, flip and flop GluR1-4 messenger RNA sequences.	methylphenyl carbinol	35-40	glutamate ionotropic receptor AMPA type subunit 1	Homo sapiens	127-132
1434539-9	1992	alpha-Thrombin enhanced the initial rate of IL-1, TNF-alpha and f-norLeu-Leu-Phe induced PMNL transendothelial migration in an additive or supradditive manner (e.g., with IL-1 alpha+alpha-thrombin, migration was 58% greater than additive at 15 to 30 minutes, p < 0.001).	methylphenyl carbinol	0-5	interleukin 1 alpha	Homo sapiens	44-48
1434539-9	1992	alpha-Thrombin enhanced the initial rate of IL-1, TNF-alpha and f-norLeu-Leu-Phe induced PMNL transendothelial migration in an additive or supradditive manner (e.g., with IL-1 alpha+alpha-thrombin, migration was 58% greater than additive at 15 to 30 minutes, p < 0.001).	methylphenyl carbinol	0-5	tumor necrosis factor	Homo sapiens	50-59
1434539-9	1992	alpha-Thrombin enhanced the initial rate of IL-1, TNF-alpha and f-norLeu-Leu-Phe induced PMNL transendothelial migration in an additive or supradditive manner (e.g., with IL-1 alpha+alpha-thrombin, migration was 58% greater than additive at 15 to 30 minutes, p < 0.001).	methylphenyl carbinol	0-5	interleukin 1 alpha	Homo sapiens	171-181
1434539-9	1992	alpha-Thrombin enhanced the initial rate of IL-1, TNF-alpha and f-norLeu-Leu-Phe induced PMNL transendothelial migration in an additive or supradditive manner (e.g., with IL-1 alpha+alpha-thrombin, migration was 58% greater than additive at 15 to 30 minutes, p < 0.001).	methylphenyl carbinol	0-5	coagulation factor II, thrombin	Homo sapiens	188-196
1279746-1	1992	A monoclonal antibody against cis-3-hexen-1-ol was prepared and used to separate and/or concentrate delta 17-6-keto-prostaglandin F1 alpha (PGF1 alpha) in the human sera.	methylphenyl carbinol	133-138	suppressor of cytokine signaling 3	Homo sapiens	30-35
1327161-8	1992	Amino-acid analysis of elastin and collagen substrates oxidized by 2:1 PQQ/Cu and then reduced with borohydride revealed that alpha-aminoadipic-delta-semialdehyde and lesser amounts of covalent cross-linkages were generated by this oxidant.	methylphenyl carbinol	126-131	elastin	Homo sapiens	23-30
1310421-5	1992	One of these groups has pK values that are significantly different from those found for alpha-thrombin, and all groups show slightly perturbed enthalpies of ionization.	methylphenyl carbinol	88-93	coagulation factor II, thrombin	Homo sapiens	94-102
2130619-2	1990	The normal quantities of TXB2 and 6-keto-PGF1 alpha produced by bovine anterior cerebral arterial smooth muscle cells were 16 +/- 5 and 464 +/- 24 pg/10(5) cells, respectively, when measured by radioimmunoassay (RIA).	methylphenyl carbinol	46-51	prostaglandin F synthase 2	Bos taurus	41-45
1676428-2	1991	Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.	methylphenyl carbinol	17-22	erb-b2 receptor tyrosine kinase 2	Homo sapiens	113-118
1676428-2	1991	Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.	methylphenyl carbinol	17-22	erb-b2 receptor tyrosine kinase 2	Homo sapiens	119-122
1368684-1	1991	Peptides that inhibit angiotensin-converting enzyme (ACE) were isolated from alpha-zein hydrolysate prepared with thermolysin.	methylphenyl carbinol	77-82	angiotensin I converting enzyme	Rattus norvegicus	53-56
1893501-1	1991	Neonatal pig testicular 20 beta-hydroxysteroid dehydrogenase (20 beta-HSD) catalyzed the oxidation of 20 beta-hydroxysteroids, 17 alpha,20 beta-dihydroxypregn-4-en-3-one and 20 beta-hydroxypregn-4-en-3-one in the presence of beta-nicotinamide adenine dinucleotide phosphate (beta-NADP+).	methylphenyl carbinol	130-136	carbonyl reductase [NADPH] 1	Sus scrofa	24-60
2130619-4	1990	Both drugs inhibited the production of TXB2 and 6-keto-PGF1 alpha in dose (1-100 mumol/L) dependent manner.	methylphenyl carbinol	60-65	prostaglandin F synthase 2	Bos taurus	55-59
2154390-1	1990	The ontogenic developmental patterns of atrial natriuretic peptide (ANP) receptors of glomeruli and inner medullary collecting tubules (IMCT) were studied by measuring the specific binding of [125I]alpha-rat ANP 1-28 ([125I]alpha-RANP) to isolated glomeruli and IMCT microdissected from collagenase-treated kidneys of young rats aged from 2 to 35 days post-partum.	methylphenyl carbinol	198-203	natriuretic peptide A	Rattus norvegicus	68-71
2171443-11	1990	Platelet-activating factor eliminated gallbladder absorption and produced net fluid secretion associated with dose-related increases in perfusate PGE concentrations and gallbladder tissue PGE and 6 keto PGF1 alpha levels when compared to control values.	methylphenyl carbinol	208-213	PCNA clamp associated factor	Homo sapiens	0-26
2137982-11	1990	When ANP was administered to in situ perfused UUO or BUO kidneys, renal vascular resistance fell significantly, and ANP induced a dramatic increase in 6-ketoprostaglandin F1 alpha production without affecting production of thromboxane B2.	methylphenyl carbinol	174-179	natriuretic peptide A	Homo sapiens	5-8
2137982-11	1990	When ANP was administered to in situ perfused UUO or BUO kidneys, renal vascular resistance fell significantly, and ANP induced a dramatic increase in 6-ketoprostaglandin F1 alpha production without affecting production of thromboxane B2.	methylphenyl carbinol	174-179	natriuretic peptide A	Homo sapiens	116-119
2154390-1	1990	The ontogenic developmental patterns of atrial natriuretic peptide (ANP) receptors of glomeruli and inner medullary collecting tubules (IMCT) were studied by measuring the specific binding of [125I]alpha-rat ANP 1-28 ([125I]alpha-RANP) to isolated glomeruli and IMCT microdissected from collagenase-treated kidneys of young rats aged from 2 to 35 days post-partum.	methylphenyl carbinol	198-203	natriuretic peptide A	Rattus norvegicus	208-211
2462500-4	1988	We show here that alpha(1-3)Dex-specific hybridomas can be established by fusion of splenic lymphocytes from xid mice to Sp2/0 myeloma cells.	methylphenyl carbinol	18-23	Bruton agammaglobulinemia tyrosine kinase	Mus musculus	109-112
2532953-1	1989	Potential substrates for UDP-GlcNAc:alpha-D-mannopyranosyl-(1----6)-N-acetyl-beta-D- glucosaminyltransferase (GnT-V).	methylphenyl carbinol	36-42	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase	Homo sapiens	110-115
2703698-5	1989	In the central nervous system (CNS) of chicken, NTE appeared to be present primarily in the somata of most neurons, but at sites indistinguishable from those of the other inhibitor-resistant and -sensitive alpha-naphthyl valerate-hydrolyzing esterases.	methylphenyl carbinol	206-211	patatin like phospholipase domain containing 6	Gallus gallus	48-51
35175724-4	2022	In this study, we fabricated a novel thin-film composite nanofiltration membrane composed of (2-hydroxypropyl)-beta-cyclodextrin (HP-beta-CD) as the chiral selector for the enantiomeric separation of racemic 1-phenylethanol chiral compounds in organic solvents.	methylphenyl carbinol	208-223	ACD shelterin complex subunit and telomerase recruitment factor	Homo sapiens	133-140
2591716-7	1989	However, after the hCG treatment, production of 17 alpha, 20 beta-dihydroxy-4-pregnen-3-one (17 alpha, 20 beta-diOHprog) and its 5 beta-reduced metabolite was markedly stimulated, while the androgen production was reduced drastically.	methylphenyl carbinol	51-57	chorionic gonadotropin subunit beta 5	Homo sapiens	19-22
7060278-1	1982	We devised a sensitive method to assay for neuraminidase activities towards alpha-(2 leads to 3)-N-acetylneuraminosyl hexasaccharide and alpha-(2 leads to 6)-N-acetylneuraminosyl hexasaccharide, which were isolated from the urine of a patient with adult sialidosis with partial deficiency of beta-galactosidase.	methylphenyl carbinol	76-83	neuraminidase 1	Homo sapiens	43-56
2415124-3	1985	alpha-hANP (7-23)NH2 fragment inhibited most effectively the specific binding of 125I-alpha-hANP to the LLC-PK1 cells, followed by alpha-hANP (17-28) and alpha-hANP (8-22), while alpha-hANP (1-6) and alpha-hANP (24-28) did not.	methylphenyl carbinol	0-5	prokineticin 1	Homo sapiens	108-111
6854093-1	1983	Pregnancy-associated alpha 2-glycoprotein (alpha 2-PAG) levels were measured in human sera by a modification of Laurell"s electroimmunoassay using rabbit anti-alpha 2-PAG serum.	methylphenyl carbinol	21-26	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	Homo sapiens	51-54
7060278-7	1982	These studies were compared with the neuraminidase activity towards alpha-(2 leads to 3)-N-acetylneuraminosyl lactose.	methylphenyl carbinol	68-75	neuraminidase 1	Homo sapiens	37-50
40990-5	1979	The fraction of alpha hemes which are pentacoordinate in fully saturated nitrosyl hemoglobin, Hb4(NO), increases from 0.0 to 0.41 over the same pH range.	methylphenyl carbinol	16-21	keratin 84	Homo sapiens	94-97
6894653-6	1981	One 2 alpha-allenyl A-nor derivative (compound 25) and one A-homo derivative (compound 34) bind almost exclusively to ABP.	methylphenyl carbinol	6-12	sex hormone binding globulin	Rattus norvegicus	118-121
29187863-6	2017	Some of the genes containing RI showed a significant reduction in transcript abundance and are involved in mitochondrial metabolism such as Isocitrate dehydrogenase (Idh), which makes alpha-KG, a co-factor needed for both DNA and histone demethylase enzymes.	methylphenyl carbinol	184-190	Isocitrate dehydrogenase	Drosophila melanogaster	140-164
33025565-1	2021	This study defines the lipase immobilization protocol and enzymatic kinetic resolution of 1-phenyl ethanol with the use of immobilized lipases (LI) as a biocatalyst.	methylphenyl carbinol	90-106	PAN0_003d1715	Moesziomyces antarcticus	23-29
30735041-6	2019	Combining in vitro and in vivo studies, we show that PtmO3 and PtmO6 are two functionally redundant alpha-ketoglutarate-dependent dioxygenases that generate a cryptic C7 beta-hydroxyl on each of the ent-kauranol and ent-atiserene scaffolds, and PtmO8 and PtmO1, a pair of NAD+/NADPH-dependent dehydrogenases, subsequently work in concert to invert the C7 beta-hydroxyl to alpha-hydroxyl via a C7 ketone intermediate.	methylphenyl carbinol	100-106	cripto, FRL-1, cryptic family 1	Homo sapiens	159-166
30119260-5	2018	In conclusion, the results indicated that alpha-MG could protect against LPS/D-GalN-induced liver failure by activating Nrf2 to induce antioxidant defense and inhibiting TLR4 signaling pathway to induce anti-inflammatory effect.	methylphenyl carbinol	42-48	galanin and GMAP prepropeptide	Mus musculus	79-83
30119260-5	2018	In conclusion, the results indicated that alpha-MG could protect against LPS/D-GalN-induced liver failure by activating Nrf2 to induce antioxidant defense and inhibiting TLR4 signaling pathway to induce anti-inflammatory effect.	methylphenyl carbinol	42-48	nuclear factor, erythroid derived 2, like 2	Mus musculus	120-124
30119260-5	2018	In conclusion, the results indicated that alpha-MG could protect against LPS/D-GalN-induced liver failure by activating Nrf2 to induce antioxidant defense and inhibiting TLR4 signaling pathway to induce anti-inflammatory effect.	methylphenyl carbinol	42-48	toll-like receptor 4	Mus musculus	170-174
30845376-5	2019	However, two SCs, alpha-pyrrolidinopropiophenone (alpha-PPP) and 4-methyl-alpha-PPP, had low muM Ki values at 5-HT2A R. In 5-HT2A R-phosphoinositide hydrolysis assays, alpha-PPP and 4-methyl-alpha-PPP displayed inverse agonist activity.	methylphenyl carbinol	18-23	5-hydroxytryptamine receptor 2A	Homo sapiens	110-116
30845376-5	2019	However, two SCs, alpha-pyrrolidinopropiophenone (alpha-PPP) and 4-methyl-alpha-PPP, had low muM Ki values at 5-HT2A R. In 5-HT2A R-phosphoinositide hydrolysis assays, alpha-PPP and 4-methyl-alpha-PPP displayed inverse agonist activity.	methylphenyl carbinol	18-23	5-hydroxytryptamine receptor 2A	Homo sapiens	123-129
30732197-5	2019	In addition, the serum levels of pork-specific IgG were significantly and positively correlated with CRP.These results suggest that alpha-Gal, the predominant natural antigen in mammalian red meat, might play a potential role in the pathogenesis of AS, and therefore, AS patients should exclude such allergenic foods, including beef, crab and pork, from their daily diet.	methylphenyl carbinol	132-138	C-reactive protein	Homo sapiens	101-104
30017190-6	2018	Moreover, alpha-LA lowered the levels of O-linked beta-N-acetylglucosamine transferase (OGT) and thioredoxin-interacting protein (TXNIP) in diabetic retinas that were more pronounced after metformin treatment of RPE cells.	methylphenyl carbinol	10-16	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	Mus musculus	41-86
30017190-6	2018	Moreover, alpha-LA lowered the levels of O-linked beta-N-acetylglucosamine transferase (OGT) and thioredoxin-interacting protein (TXNIP) in diabetic retinas that were more pronounced after metformin treatment of RPE cells.	methylphenyl carbinol	10-16	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	Mus musculus	88-91
30017190-6	2018	Moreover, alpha-LA lowered the levels of O-linked beta-N-acetylglucosamine transferase (OGT) and thioredoxin-interacting protein (TXNIP) in diabetic retinas that were more pronounced after metformin treatment of RPE cells.	methylphenyl carbinol	10-16	thioredoxin interacting protein	Mus musculus	97-128
30017190-6	2018	Moreover, alpha-LA lowered the levels of O-linked beta-N-acetylglucosamine transferase (OGT) and thioredoxin-interacting protein (TXNIP) in diabetic retinas that were more pronounced after metformin treatment of RPE cells.	methylphenyl carbinol	10-16	thioredoxin interacting protein	Mus musculus	130-135
28579060-4	2018	The disease owes its severity to the fact that LADH is the common E3 subunit of the alpha-ketoglutarate (KGDHc), pyruvate (PDHc), and branched-chain alpha-keto acid dehydrogenase complexes and is also part of the glycine cleavage system, hence the malfunctioning of LADH simultaneously incapacitates several central metabolic pathways.	methylphenyl carbinol	84-89	dihydrolipoamide dehydrogenase	Homo sapiens	66-68
29187863-6	2017	Some of the genes containing RI showed a significant reduction in transcript abundance and are involved in mitochondrial metabolism such as Isocitrate dehydrogenase (Idh), which makes alpha-KG, a co-factor needed for both DNA and histone demethylase enzymes.	methylphenyl carbinol	184-190	Isocitrate dehydrogenase	Drosophila melanogaster	166-169
27641099-0	2016	AMPK/alpha-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis.	methylphenyl carbinol	5-10	PR/SET domain 16	Homo sapiens	76-82
29137235-3	2017	Modifications to alpha-DG have been linked to a variety of cancers, where the N-terminus of alpha-DG (alpha-DG-N) is post-translationally removed by a furin-like enzyme.	methylphenyl carbinol	17-22	furin, paired basic amino acid cleaving enzyme	Homo sapiens	151-156
30653899-10	2016	In previous reports, TLR7 agonist (imiquimod) or alpha-galactosylceramide (GalCer) was used as an immune system modulator, and the expression of indoleamine 2,3-dioxygenase (IDO) or inducible nitric oxide synthase was inhibited in cancer therapies with imiquimod or GalCer.	methylphenyl carbinol	49-54	indoleamine 2,3-dioxygenase 1	Mus musculus	145-172
27798943-7	2017	Distigmine (3 x 10-7 mol/l) significantly potentiated EFS-induced contractile responses engendered in the presence of alpha,beta-mATP (10-4 mol/l), but not atropine (10-6 mol/l).	methylphenyl carbinol	118-124	solute carrier family 45, member 2	Mus musculus	129-133
27460417-3	2016	Whereas IDHs convert isocitrate to alpha-ketoglutarate (alpha-KG) with simultaneous reduction of NADP(+) to NADPH, these IDH mutants reduce alpha-KG to D-2-hydroxyglutarate (D-2-HG) while oxidizing NADPH.	methylphenyl carbinol	35-40	isocitrate dehydrogenase 1 (NADP+), soluble	Mus musculus	8-11
27068062-9	2016	CoA depletion decreased KG oxidation by alpha-ketoglutarate dehydrogenase (KGDH), such that the resulting increase in [KG] inhibited oxaloacetate removal by AST and NADH generation by MDH.	methylphenyl carbinol	40-45	malic enzyme 1	Homo sapiens	184-187
26189761-2	2015	We undertook this study to investigate the distribution of IL28B SNP rs12979860 in Mexican patients with HCV infection and to assess its usefulness in predicting response to pegylated interferon-alpha and ribavirin (PegIFN-alpha/RVB) therapy.	methylphenyl carbinol	195-200	interferon lambda 3	Homo sapiens	59-64
26077903-3	2015	The glycosylated central alpha-DG mediates adhesion, but it is obstructed by its large N terminus (alpha-DG-N); alpha-DG-N removal enables DG"s adhesive function.	methylphenyl carbinol	25-30	dystroglycan 1	Homo sapiens	31-33
26077903-3	2015	The glycosylated central alpha-DG mediates adhesion, but it is obstructed by its large N terminus (alpha-DG-N); alpha-DG-N removal enables DG"s adhesive function.	methylphenyl carbinol	99-104	dystroglycan 1	Homo sapiens	31-33
26077903-3	2015	The glycosylated central alpha-DG mediates adhesion, but it is obstructed by its large N terminus (alpha-DG-N); alpha-DG-N removal enables DG"s adhesive function.	methylphenyl carbinol	99-104	dystroglycan 1	Homo sapiens	105-107
26077903-3	2015	The glycosylated central alpha-DG mediates adhesion, but it is obstructed by its large N terminus (alpha-DG-N); alpha-DG-N removal enables DG"s adhesive function.	methylphenyl carbinol	99-104	dystroglycan 1	Homo sapiens	105-107
26560052-9	2016	Among the 33% of patients with +/-1 Ishak stage change, FS changes were not significant, but alpha-SMA increased 29-72%, and collagen increased by 12-38% (P = 0.01 for +1 only).	methylphenyl carbinol	93-98	survival of motor neuron 1, telomeric	Homo sapiens	99-102
26618894-6	2016	Complex [Re(p-NTol)Cl(L(2))(PPh3)2]PF6 (13) is the catalyst of choice for oxidation of 1-phenylethanol to acetophenone (in 80% yield; turnover number attained 290 after 30 h) and cyclooctanol to cyclooctanone (in 88% yield).	methylphenyl carbinol	87-102	protein phosphatase 4 catalytic subunit	Homo sapiens	28-32
26618894-6	2016	Complex [Re(p-NTol)Cl(L(2))(PPh3)2]PF6 (13) is the catalyst of choice for oxidation of 1-phenylethanol to acetophenone (in 80% yield; turnover number attained 290 after 30 h) and cyclooctanol to cyclooctanone (in 88% yield).	methylphenyl carbinol	87-102	sperm associated antigen 17	Homo sapiens	35-38
26334836-11	2016	We also detected some cross-frequency coupling from SMA to contralateral M1, i.e., between lower beta (14-21Hz) at the SMA and higher beta (22-30Hz) at M1 during right hand grip and between alpha (9-13Hz) at SMA and lower beta (14-21Hz) at M1 during left hand grip.	methylphenyl carbinol	190-195	survival of motor neuron 1, telomeric	Homo sapiens	52-55
26334836-11	2016	We also detected some cross-frequency coupling from SMA to contralateral M1, i.e., between lower beta (14-21Hz) at the SMA and higher beta (22-30Hz) at M1 during right hand grip and between alpha (9-13Hz) at SMA and lower beta (14-21Hz) at M1 during left hand grip.	methylphenyl carbinol	190-195	survival of motor neuron 1, telomeric	Homo sapiens	119-122
26334836-11	2016	We also detected some cross-frequency coupling from SMA to contralateral M1, i.e., between lower beta (14-21Hz) at the SMA and higher beta (22-30Hz) at M1 during right hand grip and between alpha (9-13Hz) at SMA and lower beta (14-21Hz) at M1 during left hand grip.	methylphenyl carbinol	190-195	survival of motor neuron 1, telomeric	Homo sapiens	119-122
27141681-9	2015	The results showed that EMT of A549 cells was induced by TGF-beta1, showing significant change of roundness, E-cadherion, alpha-SMA and FN (P < 0.05, P < 0.01).	methylphenyl carbinol	122-127	transforming growth factor beta 1	Homo sapiens	57-66
25413453-0	2015	Synthesis and conformational analysis of hybrid alpha/beta-dipeptides incorporating S-glycosyl-beta(2,2)-amino acids.	methylphenyl carbinol	48-54	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	95-103
25231630-4	2014	We investigated alpha-thrombin-induced changes in the cell forms of pcDNA3.1-MKN45 (MKN45/Mock), pcDNA3.1-PAR1 transfected MKN45 (MKN45/PAR1), and MKN74.	methylphenyl carbinol	16-21	coagulation factor II, thrombin	Homo sapiens	22-30