PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
11341985-2	2001	The co-treatment heat shock (HS) and proteasome inhibitor (a peptidyl aldehyde or lactacystin) showed cumulative effects on the intensity and duration of activation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) at the end of the HS period and during recovery.	peptidyl aldehyde	61-78	mitogen-activated protein kinase 8	Rattus norvegicus	168-191
11341985-2	2001	The co-treatment heat shock (HS) and proteasome inhibitor (a peptidyl aldehyde or lactacystin) showed cumulative effects on the intensity and duration of activation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) at the end of the HS period and during recovery.	peptidyl aldehyde	61-78	mitogen-activated protein kinase 8	Rattus norvegicus	193-196
11341985-2	2001	The co-treatment heat shock (HS) and proteasome inhibitor (a peptidyl aldehyde or lactacystin) showed cumulative effects on the intensity and duration of activation of c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) at the end of the HS period and during recovery.	peptidyl aldehyde	61-78	mitogen activated protein kinase 14	Rattus norvegicus	202-238
6141164-1	1984	Lysyl oxidase initiates the covalent cross-linking of elastin and collagen, converting lysyl residues in these proteins to peptidyl aldehyde residues.	peptidyl aldehyde	123-140	lysyl oxidase	Homo sapiens	0-13
6141164-1	1984	Lysyl oxidase initiates the covalent cross-linking of elastin and collagen, converting lysyl residues in these proteins to peptidyl aldehyde residues.	peptidyl aldehyde	123-140	elastin	Homo sapiens	54-61
27270938-0	2016	Peptidyl Aldehyde Specifically Interacts with Immunosubunit beta1i Proteasome: In Vitro and In Vivo Effects.	peptidyl aldehyde	0-17	proteasome 20S subunit beta 9	Homo sapiens	60-66
27270938-1	2016	We studied the effect of beta1i-specific peptidyl aldehyde IPSI-001 on proteasome from mammalian cells.	peptidyl aldehyde	41-58	proteasome 20S subunit beta 9	Homo sapiens	25-31
19541487-3	2009	Previously, we reported a series of peptidyl aldehyde and boronic acid based inhibitors of PSA.	peptidyl aldehyde	36-53	kallikrein related peptidase 3	Homo sapiens	91-94
10666314-4	2000	Two proteasome inhibitors, a peptidyl aldehyde and an epoxy ketone, which cause accumulation of ubiquitinated proteins, were found to enhance expression of stress-inducible genes, including HSP70i and the polyubiquitin genes UbB and UbC.	peptidyl aldehyde	29-46	heat shock protein family A (Hsp70) member 1A	Homo sapiens	190-196
10666314-4	2000	Two proteasome inhibitors, a peptidyl aldehyde and an epoxy ketone, which cause accumulation of ubiquitinated proteins, were found to enhance expression of stress-inducible genes, including HSP70i and the polyubiquitin genes UbB and UbC.	peptidyl aldehyde	29-46	ubiquitin B	Homo sapiens	225-228
10666314-4	2000	Two proteasome inhibitors, a peptidyl aldehyde and an epoxy ketone, which cause accumulation of ubiquitinated proteins, were found to enhance expression of stress-inducible genes, including HSP70i and the polyubiquitin genes UbB and UbC.	peptidyl aldehyde	29-46	ubiquitin C	Homo sapiens	233-236
9497367-4	1998	Treatment with peptidyl aldehyde MG132 and other proteasome inhibitors led to a steady increase in activity of c-Jun N-terminal kinase, JNK1, which is known to initiate the apoptotic program in response to certain stresses.	peptidyl aldehyde	15-32	mitogen-activated protein kinase 8	Homo sapiens	136-140
8741178-2	1996	This synthetic peptidyl aldehyde was found to be a potent and selective cathepsin L inhibitor in our screening for cysteine protease inhibitors.	peptidyl aldehyde	15-32	cathepsin L	Mus musculus	72-83
2264836-2	1990	Addition to culture media of the peptidyl aldehyde leupeptin, a non-covalent inhibitor of cathepsin L, results in the accumulation of the 20 kDa mature form of the enzyme, resulting in increased activity of cathepsin L as measured in an in vitro assay system in the absence of leupeptin.	peptidyl aldehyde	33-50	cathepsin L	Mus musculus	90-101
2264836-2	1990	Addition to culture media of the peptidyl aldehyde leupeptin, a non-covalent inhibitor of cathepsin L, results in the accumulation of the 20 kDa mature form of the enzyme, resulting in increased activity of cathepsin L as measured in an in vitro assay system in the absence of leupeptin.	peptidyl aldehyde	33-50	cathepsin L	Mus musculus	207-218
2874797-2	1986	Previous studies have pointed towards a cofactor role for pyridoxal 5"-phosphate (PLP) in lysyl oxidase, the enzyme that generates the peptidyl aldehyde precursor to the lysine-derived cross-linkages in elastin and collagen.	peptidyl aldehyde	135-152	lysyl oxidase	Bos taurus	90-103