PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 33827455-16 2021 The RBC, HCT and Hb concentration decrease with increase in RDW levels in infected children with carriage of HbSS compared to other HBB genotypes. hbss 109-113 hemoglobin subunit beta Homo sapiens 132-135 32659400-7 2020 Furthermore, we found that treatment of HBSS-induced HK-2 cells with G-Rb1 resulted in AMPK/mTOR and ERK, p38 MAPKs signaling pathways regulated autophagy inhibition. hbss 40-44 RB transcriptional corepressor 1 Mus musculus 71-74 32659400-7 2020 Furthermore, we found that treatment of HBSS-induced HK-2 cells with G-Rb1 resulted in AMPK/mTOR and ERK, p38 MAPKs signaling pathways regulated autophagy inhibition. hbss 40-44 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 87-91 32659400-7 2020 Furthermore, we found that treatment of HBSS-induced HK-2 cells with G-Rb1 resulted in AMPK/mTOR and ERK, p38 MAPKs signaling pathways regulated autophagy inhibition. hbss 40-44 mechanistic target of rapamycin kinase Homo sapiens 92-96 32659400-7 2020 Furthermore, we found that treatment of HBSS-induced HK-2 cells with G-Rb1 resulted in AMPK/mTOR and ERK, p38 MAPKs signaling pathways regulated autophagy inhibition. hbss 40-44 mitogen-activated protein kinase 1 Homo sapiens 101-104 32719598-5 2020 We topically applied various concentrations of AAT protein with a constant volume of 50 microl, prepared in Hank"s balance solution, HBSS, to epiCS cultured under bas\al condition or when culture medium supplemented with 100 microg/ml of a combined bacterial lipopolysaccharide (LPS) and peptidoglycan (PGN) mixture. hbss 133-137 serpin family A member 1 Homo sapiens 47-50 33193944-6 2020 Electrochemical corrosion and immersion tests proved that the corrosion resistance of MAF-treated AZ31 Mg alloy was significantly improved compared with untreated AZ31 Mg alloy in HBSS (Hank"s Balanced Salt Solution). hbss 180-184 MAF bZIP transcription factor Homo sapiens 86-89 32744516-5 2020 The DC-ERG technique uses glass capillaries filled with Hank"s buffered salt solution (HBSS) to measure the slower electrical responses of the RPE elicited from light-evoked concentration changes in the subretinal space due to photoreceptor activity. hbss 87-91 ETS transcription factor Mus musculus 7-10 31050380-9 2020 In gene set enrichment analysis, the shared differentially expressed genes in HBSS and milk were associated with the TNF-alpha signaling pathway (P = 1.07E-7 ). hbss 78-82 tumor necrosis factor Homo sapiens 117-126 31982521-4 2020 The caspase-3 activity was induced by CASS > HBSS > DASS > CHSS, with the maximum multiple of 2.954 +- 0.103. hbss 45-49 caspase 3 Homo sapiens 4-13 31600247-4 2019 The results showed that accuracy of ATP analysis was significantly improved by adding coenzyme A (CoA) and signal attenuation of ATP analysis was greatly postponed by adding bovine serum albumin (BSA) both in Hank"s balanced salt solution (HBSS) and Tyrode"s buffer. hbss 240-244 albumin Homo sapiens 181-194 31442466-5 2019 We first found that incubation of model molecules, such as transferrin (Tf) and cholera toxin subunit B (CTB), in cell culture medium (DMEM) could efficiently induce their internalization to HeLa cells compared to that in transport buffer (HBSS). hbss 240-244 transferrin Homo sapiens 59-70 31442466-5 2019 We first found that incubation of model molecules, such as transferrin (Tf) and cholera toxin subunit B (CTB), in cell culture medium (DMEM) could efficiently induce their internalization to HeLa cells compared to that in transport buffer (HBSS). hbss 240-244 transferrin Homo sapiens 72-74 31442466-5 2019 We first found that incubation of model molecules, such as transferrin (Tf) and cholera toxin subunit B (CTB), in cell culture medium (DMEM) could efficiently induce their internalization to HeLa cells compared to that in transport buffer (HBSS). hbss 240-244 phosphate cytidylyltransferase 1B, choline Homo sapiens 80-103 31442466-5 2019 We first found that incubation of model molecules, such as transferrin (Tf) and cholera toxin subunit B (CTB), in cell culture medium (DMEM) could efficiently induce their internalization to HeLa cells compared to that in transport buffer (HBSS). hbss 240-244 phosphate cytidylyltransferase 1B, choline Homo sapiens 105-108 31240733-7 2019 In 7.3% (4/55) of the HbSS group, there was stillbirth, and in these cases, PAPP-A was less than or equal to 0.5 MoM; in the control group, the incidence of stillbirth was lower (1%; P < .001). hbss 22-26 pappalysin 1 Homo sapiens 76-82 31331356-12 2019 RESULTS: HMGB1 was a critical regulator of autophagy-mediated NIS degradation in HBSS-treated FTC-133/TPC-1 cells. hbss 81-85 high mobility group box 1 Homo sapiens 9-14 31331356-3 2019 Here the authors intended to identify the role of HMGB1 in Hank"s balanced salt solution (HBSS)-induced autophagy, explore NIS protein degradation through a autophagy-lysosome pathway in thyroid cancer cells and elucidate the possible molecular mechanisms. hbss 90-94 high mobility group box 1 Homo sapiens 50-55 31331356-14 2019 HMGB1-knockdown dramatically suppressed autophagy, NIS degradation and boosted iodide uptake in HBSS-treated cells. hbss 96-100 high mobility group box 1 Homo sapiens 0-5 31331356-15 2019 Moreover, HBSS enhanced ROS-sustained autophagy and promoted the cytosolic translocation of HMGB1. hbss 10-14 high mobility group box 1 Homo sapiens 92-97 30014739-11 2018 ATP contents were significantly different in OMCSs stored in MEM or HBSS at 22 C and 4 C. LDH release was significantly different in OMCSs stored in HBSS at 22 C and 4 C. The highest LDH release was observed in OMCSs stored in HBSS at 37 C. ALP activities and osteocalcin contents were the lowest in implanted OMCSs stored in HBSS at 37 C at four weeks after subcutaneous implantation. hbss 149-153 bone gamma-carboxyglutamate protein Rattus norvegicus 260-271 30860192-6 2019 Results: We found higher complication rate in HbSS group, commonest complications being vaso-occlusive crisis (RR 1.47, 95% CI 1.22 - 1.78), pregnancy induced hypertension (RR 1.31, 95% CI 1.08 - 1.57), urinary tract infection (RR 1.32, 95% CI 1.12 - 1.57), and intrauterine growth restriction (RR 1.2, 95% CI 1.05 - 1.34). hbss 46-50 ribonucleotide reductase catalytic subunit M1 Homo sapiens 111-115 30860192-6 2019 Results: We found higher complication rate in HbSS group, commonest complications being vaso-occlusive crisis (RR 1.47, 95% CI 1.22 - 1.78), pregnancy induced hypertension (RR 1.31, 95% CI 1.08 - 1.57), urinary tract infection (RR 1.32, 95% CI 1.12 - 1.57), and intrauterine growth restriction (RR 1.2, 95% CI 1.05 - 1.34). hbss 46-50 ribonucleotide reductase catalytic subunit M1 Homo sapiens 173-177 30258463-7 2018 We found that the number of viable cells harvested per gram of adipose tissue mass was higher in UW solution- than HBSS-preserved tissue. hbss 115-119 WD and tetratricopeptide repeats 1 Mus musculus 63-70 30860192-6 2019 Results: We found higher complication rate in HbSS group, commonest complications being vaso-occlusive crisis (RR 1.47, 95% CI 1.22 - 1.78), pregnancy induced hypertension (RR 1.31, 95% CI 1.08 - 1.57), urinary tract infection (RR 1.32, 95% CI 1.12 - 1.57), and intrauterine growth restriction (RR 1.2, 95% CI 1.05 - 1.34). hbss 46-50 ribonucleotide reductase catalytic subunit M1 Homo sapiens 173-177 30860192-6 2019 Results: We found higher complication rate in HbSS group, commonest complications being vaso-occlusive crisis (RR 1.47, 95% CI 1.22 - 1.78), pregnancy induced hypertension (RR 1.31, 95% CI 1.08 - 1.57), urinary tract infection (RR 1.32, 95% CI 1.12 - 1.57), and intrauterine growth restriction (RR 1.2, 95% CI 1.05 - 1.34). hbss 46-50 ribonucleotide reductase catalytic subunit M1 Homo sapiens 173-177 27546026-7 2016 For the HbSS group, when compared to the control group, the following genes showed differential expression: IL1RAP (2.76-fold), BCL6 (4.49-fold), CXCL10 (-2.12-fold), CXCR1 (-3.66-fold), and C3 (-2.0-fold). hbss 8-12 interleukin 1 receptor accessory protein Homo sapiens 108-114 28715096-7 2017 In the HBSS groups, RUNX2 expression increased showing a direction to osteogenic differentiation of PDL fibroblasts. hbss 7-11 RUNX family transcription factor 2 Homo sapiens 20-25 28768505-2 2017 Additionally, down-regulation of the let-7 miRNAs in cultured adult CD34(+) cells or the over-expression of LIN28 in cultured erythrocytes from pediatric patients with HbSS genotype causes increased levels of fetal hemoglobin (HbF) in the range of 19-40% of the total. hbss 168-172 lin-28 homolog A Homo sapiens 108-113 27546026-7 2016 For the HbSS group, when compared to the control group, the following genes showed differential expression: IL1RAP (2.76-fold), BCL6 (4.49-fold), CXCL10 (-2.12-fold), CXCR1 (-3.66-fold), and C3 (-2.0-fold). hbss 8-12 BCL6 transcription repressor Homo sapiens 128-132 28058255-11 2016 In addition, in pH 6.5 or pH 7.3 HBSS buffer, the expression levels of cell stress (p53) and apoptosis (caspase-3, Bcl-xL) markers were significantly lower in cardiomyocytes treated with 50 mM L-glutamine than those without L-glutamine (RT-PCR). hbss 33-37 Wistar clone pR53P1 p53 pseudogene Rattus norvegicus 84-87 27546026-7 2016 For the HbSS group, when compared to the control group, the following genes showed differential expression: IL1RAP (2.76-fold), BCL6 (4.49-fold), CXCL10 (-2.12-fold), CXCR1 (-3.66-fold), and C3 (-2.0-fold). hbss 8-12 C-X-C motif chemokine ligand 10 Homo sapiens 146-152 27546026-7 2016 For the HbSS group, when compared to the control group, the following genes showed differential expression: IL1RAP (2.76-fold), BCL6 (4.49-fold), CXCL10 (-2.12-fold), CXCR1 (-3.66-fold), and C3 (-2.0-fold). hbss 8-12 C-X-C motif chemokine receptor 1 Homo sapiens 167-172 27678389-8 2016 CONCLUSIONS: The lower plasma renin concentration at 16 weeks with HbSS could be either primary or secondary to vasoconstriction related to inadequate vasodilator activity. hbss 67-71 renin Homo sapiens 30-35 27581177-2 2016 Basic amino acids improved insulin solubility in water while 200 and 400 mug/mL lysine significantly increased insulin solubility in HBSS. hbss 133-137 insulin Homo sapiens 111-118 28058255-11 2016 In addition, in pH 6.5 or pH 7.3 HBSS buffer, the expression levels of cell stress (p53) and apoptosis (caspase-3, Bcl-xL) markers were significantly lower in cardiomyocytes treated with 50 mM L-glutamine than those without L-glutamine (RT-PCR). hbss 33-37 caspase 3 Rattus norvegicus 104-113 28058255-11 2016 In addition, in pH 6.5 or pH 7.3 HBSS buffer, the expression levels of cell stress (p53) and apoptosis (caspase-3, Bcl-xL) markers were significantly lower in cardiomyocytes treated with 50 mM L-glutamine than those without L-glutamine (RT-PCR). hbss 33-37 Bcl2-like 1 Rattus norvegicus 115-121 25565629-7 2015 BI-2536 increased p62, LC3B-I and GFP-LC3 punctae, and inhibited HBSS-induced degradation of p62, suggesting that PLK1 inhibition attenuates autophagy. hbss 65-69 nucleoporin 62 Homo sapiens 93-96 25578401-5 2015 In the present study, we explored the mechanisms whereby HMGB1 regulates tumor cell autophagy during nutrient depletion (the cells were cultured in Hank"s balanced salt solution, HBSS). hbss 179-183 high mobility group box 1 Homo sapiens 57-62 26390657-10 2015 CONCLUSION: Emodin could inhibit HBSS-induced LC3 II protein expression and the activation of autophagy in NRK-52E cells, and the effect of blocking autophagy may be mediated through mTOR signaling pathway. hbss 33-37 mechanistic target of rapamycin kinase Rattus norvegicus 183-187 25565629-7 2015 BI-2536 increased p62, LC3B-I and GFP-LC3 punctae, and inhibited HBSS-induced degradation of p62, suggesting that PLK1 inhibition attenuates autophagy. hbss 65-69 polo like kinase 1 Homo sapiens 114-118 25775774-3 2014 After the intervention of HBSS for 0, 0.5,1, 2 and 6 hours, firstly, the protein expression of microtubule-associated protein 1 light chain 3(LC3 I/II), which is a key protein in autophagy, was detected. hbss 26-30 annexin A3 Rattus norvegicus 142-145 25775774-9 2014 CONCLUSION: HBSS induces autophagy in renal tubular epithelial cells by inhibiting mTOR signaling pathway activation. hbss 12-16 mechanistic target of rapamycin kinase Rattus norvegicus 83-87 25775774-6 2014 RESULT: HBSS could induce the up-regulation of LC3 II and the down-regulation of p-mTOR S2448 at protein expression level in NRK-52E cells. hbss 8-12 annexin A3 Rattus norvegicus 47-50 25775774-6 2014 RESULT: HBSS could induce the up-regulation of LC3 II and the down-regulation of p-mTOR S2448 at protein expression level in NRK-52E cells. hbss 8-12 mechanistic target of rapamycin kinase Rattus norvegicus 83-87 20709907-6 2010 We further demonstrate that increased miR-144 is associated with reduced NRF2 levels in HbSS reticulocytes and with decreased glutathione regeneration and attenuated antioxidant capacity in HbSS erythrocytes, thereby providing a possible mechanism for the reduced oxidative stress tolerance and increased anemia severity seen in HbSS patients. hbss 88-92 microRNA 144 Homo sapiens 38-45 24483841-6 2014 RESULTS: Angiogenin level was significantly higher in patients with SCD [250 (100-300) pg/mL] compared to beta-TM [180 (140-230) pg/mL] and controls [89 (80-103) pg/mL] (P < .001) especially those with HbSS (P = .06). hbss 205-209 angiogenin Homo sapiens 9-19 21830237-4 2011 Following treatment with AMD3100, a specific inhibitor of CXCR4, mice recovering from widespread demyelination exhibit a significant (P < 0.01) increase in the number of OPCs and fewer (P < 0.05) mature oligodendrocytes compared with HBSS-treated animals. hbss 240-244 chemokine (C-X-C motif) receptor 4 Mus musculus 58-63 23376776-3 2013 In this study, we demonstrate that starvation of HeLa cells by incubation with Hank"s buffered salt solution (HBSS) induced cell apoptosis, which was accompanied by the induction of reactive oxygen species (ROS) production and AMP-activated protein kinase (AMPK) phosphorylation. hbss 110-114 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 227-255 23376776-3 2013 In this study, we demonstrate that starvation of HeLa cells by incubation with Hank"s buffered salt solution (HBSS) induced cell apoptosis, which was accompanied by the induction of reactive oxygen species (ROS) production and AMP-activated protein kinase (AMPK) phosphorylation. hbss 110-114 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 257-261 23376776-5 2013 We found that HBSS starvation rapidly induced pyruvate dehydrogenase kinase (PDK) activation and pyruvate dehydrogenase (PDH) phosphorylation, both of which were inhibited by compound C (an AMPK inhibitor), NAC (a ROS scavenger), and the dominant negative mutant of AMPK. hbss 14-18 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 46-68 23376776-5 2013 We found that HBSS starvation rapidly induced pyruvate dehydrogenase kinase (PDK) activation and pyruvate dehydrogenase (PDH) phosphorylation, both of which were inhibited by compound C (an AMPK inhibitor), NAC (a ROS scavenger), and the dominant negative mutant of AMPK. hbss 14-18 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 97-119 23376776-5 2013 We found that HBSS starvation rapidly induced pyruvate dehydrogenase kinase (PDK) activation and pyruvate dehydrogenase (PDH) phosphorylation, both of which were inhibited by compound C (an AMPK inhibitor), NAC (a ROS scavenger), and the dominant negative mutant of AMPK. hbss 14-18 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 121-124 23376776-5 2013 We found that HBSS starvation rapidly induced pyruvate dehydrogenase kinase (PDK) activation and pyruvate dehydrogenase (PDH) phosphorylation, both of which were inhibited by compound C (an AMPK inhibitor), NAC (a ROS scavenger), and the dominant negative mutant of AMPK. hbss 14-18 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 190-194 23376776-5 2013 We found that HBSS starvation rapidly induced pyruvate dehydrogenase kinase (PDK) activation and pyruvate dehydrogenase (PDH) phosphorylation, both of which were inhibited by compound C (an AMPK inhibitor), NAC (a ROS scavenger), and the dominant negative mutant of AMPK. hbss 14-18 X-linked Kx blood group Homo sapiens 207-210 23376776-5 2013 We found that HBSS starvation rapidly induced pyruvate dehydrogenase kinase (PDK) activation and pyruvate dehydrogenase (PDH) phosphorylation, both of which were inhibited by compound C (an AMPK inhibitor), NAC (a ROS scavenger), and the dominant negative mutant of AMPK. hbss 14-18 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 266-270 23376776-7 2013 Moreover, DCA (a PDK inhibitor), NAC, and compound C all significantly decreased HBSS starvation-induced lactate production accompanied by enhancement of HBSS starvation-induced cell apoptosis. hbss 81-85 X-linked Kx blood group Homo sapiens 33-36 23376776-7 2013 Moreover, DCA (a PDK inhibitor), NAC, and compound C all significantly decreased HBSS starvation-induced lactate production accompanied by enhancement of HBSS starvation-induced cell apoptosis. hbss 154-158 X-linked Kx blood group Homo sapiens 33-36 23376776-8 2013 Not only in HeLa cells, HBSS-induced lactate production and PDH phosphorylation were also observed in CL1.5, A431 and human umbilical vein endothelial cells. hbss 24-28 pyruvate dehydrogenase phosphatase catalytic subunit 1 Homo sapiens 60-63 20709907-6 2010 We further demonstrate that increased miR-144 is associated with reduced NRF2 levels in HbSS reticulocytes and with decreased glutathione regeneration and attenuated antioxidant capacity in HbSS erythrocytes, thereby providing a possible mechanism for the reduced oxidative stress tolerance and increased anemia severity seen in HbSS patients. hbss 88-92 NFE2 like bZIP transcription factor 2 Homo sapiens 73-77 19900551-12 2010 Ductal injection of oxygenated PFC significantly reduced ADP/ATP ratio (8.57+/-0.6 vs. 14.2+/-2.4, p<0.03) and improved intracellular energy charge (0.36+/-0.05 vs. 0.22+/-0.03, p<0.001) as compared to HBSS group. hbss 208-212 complement factor properdin Rattus norvegicus 31-34 10565612-7 1999 Additionally, CM-IL1beta, but not control CM, slowed the changes in Mac-1 and CR1 cell surface expression that occurred in HBSS within 2 h of incubation. hbss 123-127 interleukin 1 beta Homo sapiens 17-24 18173663-10 2008 About 110 of 140 specimens in the SCCM and 101 of 140 specimens in the HBSS group showed PCNA-positive cells. hbss 71-75 proliferating cell nuclear antigen Homo sapiens 89-93 15618128-13 2005 However, CRP was significantly associated with REE in HbSS (r = 0.8, P = 0.003) and an important predictor of REE/FFM. hbss 54-58 C-reactive protein Homo sapiens 9-12 19019426-9 2009 HAM frozen at -80 degrees C in Hank"s Balanced Salt Solution (HBSS) was superior, demonstrating excellent morphology of cultured LECs and high levels of deltaN-p63alpha (< or =68%) and ABCG2 (< or =62%) expression (p<0.001). hbss 62-66 tumor protein p63 Homo sapiens 160-168 16904968-7 2006 Neutrophil CD66b expression was determined by flow cytometry in blood treated with HBSS, fMLP (1 micromol/L), supernatant + fMLP, or supernatant + fMLP + PTX. hbss 83-87 CEA cell adhesion molecule 8 Homo sapiens 11-16 12656842-8 2003 Supplementation of HBSS with catalase resulted in a lower level of surface resorption (48.6%) that was statistically significant (P < 0.05). hbss 19-23 catalase Canis lupus familiaris 29-37 12656842-10 2003 The improvement observed with catalase-supplemented HBSS was confined to the 45-min incubation period; only Viaspan - or + catalase reduced surface resorption at the 5- and 26-h incubations. hbss 52-56 catalase Canis lupus familiaris 30-38 11219489-6 2001 Administration of CRIP-IL-12 significantly reduced tumor metastasis in liver measured by number of foci (CRIP- IL-12: 45.2 +/- 36.7, CRIP-lacZ: >250, HBSS: >250, P<.05) and by liver weight (CRIP-IL-12: 13.0+/-2.5 g, CRIP-lacZ: 30.4+/-8.5 g, HBSS: 26.0+/-7.6 g, P<.05). hbss 153-157 cysteine rich protein 1 Rattus norvegicus 18-22 11219489-6 2001 Administration of CRIP-IL-12 significantly reduced tumor metastasis in liver measured by number of foci (CRIP- IL-12: 45.2 +/- 36.7, CRIP-lacZ: >250, HBSS: >250, P<.05) and by liver weight (CRIP-IL-12: 13.0+/-2.5 g, CRIP-lacZ: 30.4+/-8.5 g, HBSS: 26.0+/-7.6 g, P<.05). hbss 153-157 interleukin 12B Rattus norvegicus 23-28 10565612-7 1999 Additionally, CM-IL1beta, but not control CM, slowed the changes in Mac-1 and CR1 cell surface expression that occurred in HBSS within 2 h of incubation. hbss 123-127 integrin subunit beta 2 Homo sapiens 68-73 10565612-7 1999 Additionally, CM-IL1beta, but not control CM, slowed the changes in Mac-1 and CR1 cell surface expression that occurred in HBSS within 2 h of incubation. hbss 123-127 complement C3b/C4b receptor 1 (Knops blood group) Homo sapiens 78-81 9821178-11 1998 The islet viability was lowest in the HBSS group immediately after purification (vs. LAP-1, oUW, and mUW, p < 0.05) and further decreased during culture (p < 0.01). hbss 38-42 torsin 1A interacting protein 1 Homo sapiens 85-90 9374740-5 1997 Activated eosinophils [6 x 10(6)/ml, suspended in Hanks" buffered salt solution (HBSS)] applied to cultured DRG neurons for 30 min increased basal SP release 2.4-fold compared with HBSS-exposed neurons (activated eosinophils 11.10 +/- 2.48% vs. HBSS 4.59 +/- 0.99%; P = 0.002), whereas neither nonactivated eosinophils nor cytochalasin B and FMLP in HBSS influenced SP release. hbss 81-85 formyl peptide receptor 1 Homo sapiens 342-346 9248694-6 1997 Now the tooth is kept bathed in an emesis basin filled with HBSS, which maintains the viability of the PDL for 30 minutes. hbss 60-64 programmed cell death 1 Homo sapiens 103-106 8602630-5 1996 Compared to normals, both steady-state and in-crisis HbSS patients had significantly (P < 0.001) depressed platelet TSP-1 content (82.6 +/- 11.9, 47.1 +/- 16.0 and 45.9 +/- 20.7 ng/l0(6) platelets, respectively, mean +/- SD). hbss 53-57 thrombospondin 1 Homo sapiens 119-124 7541361-6 1995 Resting grids of 10(-5) M cytochalasin E-treated platelets on drops of HBSS for 15 min restored their ability to clear FGN/Au linked to GPIIb-IIIa from exposed surfaces to the OCS, but 10(-4) M cytochalasin E-treated cells remained anergic after incubation on drops of HBSS. hbss 71-75 integrin subunit alpha 2b Homo sapiens 136-141 9052987-4 1996 In HBSS + Ca2+ (1.37 mM), EGF treatment resulted in a transient increase in [Ca2+]i from 75 to 150 nM, which lasted approximately 3.5 min and re-equilibrated to 90 nM. hbss 3-7 epidermal growth factor Homo sapiens 26-29 9052987-4 1996 In HBSS + Ca2+ (1.37 mM), EGF treatment resulted in a transient increase in [Ca2+]i from 75 to 150 nM, which lasted approximately 3.5 min and re-equilibrated to 90 nM. hbss 3-7 carbonic anhydrase 2 Homo sapiens 77-80 9052987-5 1996 In nominally Ca(2+)-free (2-5 muM) HBSS, EGF caused a [Ca2+]i elevation that peaked at 140 nM and returned to baseline. hbss 35-39 epidermal growth factor Homo sapiens 41-44 7579086-4 1995 The pHi of PM phi was measured fluorometrically in N-hydroxyethylpiperazine-N"-2-ethanesulfonic acid (HEPES)-buffered salt solution (HBSS) or CDS at pH values of 5.3, 6.5, and 7.0, values that represent the pH existing in dialysate during the first 30 min of dwell time. hbss 133-137 glucose-6-phosphate isomerase Homo sapiens 4-7 7579086-4 1995 The pHi of PM phi was measured fluorometrically in N-hydroxyethylpiperazine-N"-2-ethanesulfonic acid (HEPES)-buffered salt solution (HBSS) or CDS at pH values of 5.3, 6.5, and 7.0, values that represent the pH existing in dialysate during the first 30 min of dwell time. hbss 133-137 glucose-6-phosphate isomerase Homo sapiens 14-17 7579086-5 1995 For any given pH of the experimental medium, the pHi was always more acidic in CDS than in HBSS. hbss 91-95 glucose-6-phosphate isomerase Homo sapiens 49-52 7579086-6 1995 When PM phi were incubated with a lactate-containing HBSS, a cellular acidification was observed that was similar to that attained by exposure to CDS at the same pH. hbss 53-57 glucose-6-phosphate isomerase Homo sapiens 8-11 7684769-4 1993 Tf and hp levels were significantly reduced in the HbSS groups relative to the control group. hbss 51-55 transferrin Homo sapiens 0-2 7850770-5 1995 GC3/c1 cells after 1 mM treatment in Ca(2+)-free HBSS showed no rise of [Ca2+]i. hbss 49-53 ankyrin repeat domain 36 Mus musculus 0-3 1396416-3 1992 In nominal HCO3(-)-free HEPES-buffered Hanks" balanced salt solution (HEPES HBSS), when the pH of medium (pHo) was maintained at 7.4, the steady-state pHi of cultured astrocytes from DBA mice was 6.98 +/- 0.03, and that from C57 mice was 7.01 +/- 0.03. hbss 76-80 glucose-6-phosphate isomerase 1 Mus musculus 151-154 1396416-4 1992 When the cells were incubated in HBSS containing 25 mM HCO3- and equilibrated with 5% CO2 (HCO3- HBSS, pHo = 7.4), pHi of both DBA and C57 astrocytes was approximately 0.1-0.15 pH units higher than that in HEPES HBSS. hbss 33-37 glucose-6-phosphate isomerase 1 Mus musculus 115-118 1396416-4 1992 When the cells were incubated in HBSS containing 25 mM HCO3- and equilibrated with 5% CO2 (HCO3- HBSS, pHo = 7.4), pHi of both DBA and C57 astrocytes was approximately 0.1-0.15 pH units higher than that in HEPES HBSS. hbss 97-101 glucose-6-phosphate isomerase 1 Mus musculus 115-118 1396416-4 1992 When the cells were incubated in HBSS containing 25 mM HCO3- and equilibrated with 5% CO2 (HCO3- HBSS, pHo = 7.4), pHi of both DBA and C57 astrocytes was approximately 0.1-0.15 pH units higher than that in HEPES HBSS. hbss 97-101 glucose-6-phosphate isomerase 1 Mus musculus 115-118 1396416-9 1992 SITS, an anion transport inhibitor, decreased the pHi of both DBA and C57 astrocytes in HCO3- HBSS but not in HEPES HBSS. hbss 94-98 glucose-6-phosphate isomerase 1 Mus musculus 50-53 34470050-6 2021 Children with HbSS had greater leukocytosis but significantly lower concentrations of several plasma inflammatory cytokines, including TNF-alpha. hbss 14-18 tumor necrosis factor Homo sapiens 135-144 1396416-13 1992 It also enhanced the response of pHi to changing pHo and [Na+]o in HEPES HBSS. hbss 73-77 glucose-6-phosphate isomerase 1 Mus musculus 33-36 34895288-10 2021 RESULTS: The mean +- SD of serum AMH level in women with HbSS was 3.64 +- 0.65 ng/mL and was lower than that of women with HbAA 7.35 +-1.19 ng/mL (p < 0.001). hbss 57-61 anti-Mullerian hormone Homo sapiens 33-36 33624556-5 2021 Untreated HbSS mice exhibited increased proteinuria, elevated plasma endothelin-1 (ET-1), and reduced urine concentrating ability compared to HbAA mice. hbss 10-14 endothelin 1 Mus musculus 69-81 35615929-10 2022 Systemic and intraplantar administration of KT109, an inhibitor of DAGLbeta, decreased mechanical and heat hyperalgesia in HbSS mice. hbss 123-127 diacylglycerol lipase, alpha Mus musculus 67-75 3068033-9 1988 Cyclic voltammetry of ascorbic acid, AZQ, and adriamycin in Hank"s Balanced Salt Solution (HBSS pH 7.5), the buffer used for biological measurements, showed that the oxidation peak potential for ascorbic acid (Eap = +0.43 V) is closer to the reduction peak potential for AZQ (Ecp = -0.36 V) than that for adriamycin (Ecp = -0.67 V). hbss 91-95 alkaline phosphatase, placental-like 2 Mus musculus 210-213 35159951-7 2022 The results showed a higher level of exosomal let-7i-5p and miR-451a in HbSS-. hbss 72-76 microRNA 451a Homo sapiens 60-68 2591455-8 1989 Moreover, it appeared that the expression of thermotolerance was strongly dependent on medium conditions: the thermotolerance ratio (TTR, ratio between slopes of survival curves of thermotolerant and normal cells) was much lower at low pH or in cells heated in HBSS. hbss 261-265 transthyretin Mus musculus 133-136 33624556-5 2021 Untreated HbSS mice exhibited increased proteinuria, elevated plasma endothelin-1 (ET-1), and reduced urine concentrating ability compared to HbAA mice. hbss 10-14 endothelin 1 Mus musculus 83-87 33624556-6 2021 Hydroxyurea reduced proteinuria and plasma ET-1 levels in HbSS mice. hbss 58-62 endothelin 1 Mus musculus 43-47