PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3758193-1 1986 In this study we investigated the affinity of several 4-chlorinated and 1-ene derivatives of 17 alpha-methyltestosterone (MT) and 17 alpha-methyl-5 alpha-dihydrotestosterone (MDHT) to the androgen receptor, and, additionally, the effect of a few MT-derived steroids on the activity of the 5 alpha-reductase enzyme present in the rat seminal vesicle. mestanolone 130-173 androgen receptor Rattus norvegicus 188-205 31884045-6 2020 Mesterolone, mestanolone and methenolone increased mineralocorticoid but decreased adrenal androgen production, indicating CYP17A1 dysfunction. mestanolone 13-24 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 123-130