PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32347981-8 2021 The saturated aldehydes Nonanal and Decanal (known skin metabolites) and the aromatic aldehyde Benzaldehyde (known skin and Staphylococcus epidermidis metabolite) were shown to induce the Nrf2-keap1 pathway in human keratinocytes. benzaldehyde 95-107 NFE2 like bZIP transcription factor 2 Homo sapiens 188-192 32559510-1 2020 An efficient three component coupling of aromatic aldehyde, deoxy sugar based alkyne (alpha-2-deoxy propargyl glycoside) and heterocyclic amine have been refluxed to synthesize stereoselective chiral propargylamines with good to excellent yield using only CuI catalyst along with bifunctional ligand l-proline. benzaldehyde 41-58 glycoprotein hormone subunit alpha 2 Homo sapiens 86-93 32559510-4 2020 The ligand l-proline was used for the first time in enantioselective A3-coupling reaction of alpha-2-deoxy propargyl glycosides involving substituted aromatic aldehyde and heterocyclic amines. benzaldehyde 150-167 glycoprotein hormone subunit alpha 2 Homo sapiens 93-100 32496054-12 2020 Cinnamaldehyde and benzaldehyde were found to be the most potent inhibitors of microsomal CYP2A6 of the flavoring agents tested, with identified IC50 values of 1.1 muM and 3.0 muM, respectively. benzaldehyde 19-31 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 90-96 33063315-9 2020 Moreover, ethyl butyrate, benzaldehyde, and 2-heptanone, when added, had evident inhibitory or masking effects on the AI of "sour," "rancid," and "animalic (goat)" attributes. benzaldehyde 26-38 membrane bound O-acyltransferase domain containing 4 Homo sapiens 157-161 32846602-5 2020 The Strecker aldehydes benzaldehyde and 2-methylbutanal resulted as effective markers to correlate with the initial lactase purity during storage. benzaldehyde 23-35 lactase Homo sapiens 116-123 33533423-3 2020 Compounds 4-X-benzylidene-4-carboxy aniline (X = H, F, Cl, Br, CH3, OCH3) 1b-6b were synthesized by the reaction of benzaldehyde and its substituted derivatives with 4-aminobenzoic acid using absolute ethanol as the solvent. benzaldehyde 116-128 chromosome 12 open reading frame 73 Homo sapiens 59-61 32347981-8 2021 The saturated aldehydes Nonanal and Decanal (known skin metabolites) and the aromatic aldehyde Benzaldehyde (known skin and Staphylococcus epidermidis metabolite) were shown to induce the Nrf2-keap1 pathway in human keratinocytes. benzaldehyde 95-107 kelch like ECH associated protein 1 Homo sapiens 193-198 31066398-3 2019 Treatment of 6a with non-conjugated small molecules such as phenyl isocyanates, phenyl isothiocyanate, and benzaldehyde resulted in formation of Sc/gamma-C [4 + 2] cycloaddition products 7-9 because of nucleophilic reactivity at the beta-diketiminato gamma-carbon, with retention of ScP interactions. benzaldehyde 107-119 interleukin 2 receptor subunit gamma Homo sapiens 148-155 31113817-6 2019 Gene-drug pairings linked by pathways or functions show specific correlations to isoforms compared with composite gene expression, including ALKBH2-benzaldehyde, AKT3-vandetanib, BCR-imatinib, CDK1 and 20-palbociclib, CASP1-imexon, and FGFR3-pazopanib. benzaldehyde 148-160 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase Homo sapiens 141-147 31066398-3 2019 Treatment of 6a with non-conjugated small molecules such as phenyl isocyanates, phenyl isothiocyanate, and benzaldehyde resulted in formation of Sc/gamma-C [4 + 2] cycloaddition products 7-9 because of nucleophilic reactivity at the beta-diketiminato gamma-carbon, with retention of ScP interactions. benzaldehyde 107-119 urocortin 3 Homo sapiens 283-286 30768969-13 2019 The most efficient of the tested substrates were comparable to benzaldehyde and p-anisaldehyde known as the best aromatic aldehyde substrates of plant cytosolic ALDH2s in vitro. benzaldehyde 63-75 aldehyde dehydrogenase 2 Zea mays 161-166 30768969-13 2019 The most efficient of the tested substrates were comparable to benzaldehyde and p-anisaldehyde known as the best aromatic aldehyde substrates of plant cytosolic ALDH2s in vitro. benzaldehyde 113-130 aldehyde dehydrogenase 2 Zea mays 161-166 30521138-4 2019 Presented in this report are the synthesis and biological evaluation of ALDH1A1-selective chemical probes composed of an aromatic aldehyde derived from N,N-diethylamino benzaldehyde (DEAB) linked to a fluorinated pyridine ring either via an amide or amine linkage. benzaldehyde 121-138 aldehyde dehydrogenase 1 family member A1 Homo sapiens 72-79 30543227-5 2019 X-ray photoelectron spectroscopy reveals that the high ratio of Pd2+ to Pd0 in the surface of Pd-Pb NPs enhances the benzaldehyde productivity, and the electronic modification of the Pd3Pb NCs boosts the benzaldehyde selectivity. benzaldehyde 117-129 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 64-67 30543227-5 2019 X-ray photoelectron spectroscopy reveals that the high ratio of Pd2+ to Pd0 in the surface of Pd-Pb NPs enhances the benzaldehyde productivity, and the electronic modification of the Pd3Pb NCs boosts the benzaldehyde selectivity. benzaldehyde 204-216 PAF1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 64-67 30382490-3 2019 OBJECTIVES: The aim of this work was to study the effect of five important phenothiazine drugs on AOX activity using benzaldehyde and phenanthridine as aldehyde and N-heterocyclic substrates, respectively. benzaldehyde 117-129 acyl-CoA oxidase 1 Rattus norvegicus 98-101 30382490-6 2019 RESULTS: All phenothiazines could inhibit AOX activity measured either by phenanthridine or benzaldehyde with almost no effect on XO activity. benzaldehyde 92-104 acyl-CoA oxidase 1 Rattus norvegicus 42-45 30382490-7 2019 In the case of benzaldehyde oxidation, the lowest and highest half-maximal inhibitory concentration (IC50) values were obtained for promethazine (IC50 = 0.9 microM), and trifluoperazine (IC50 = 3.9 microM), respectively; whereas perphenazine (IC50 = 4.3 microM), and trifluoperazine (IC50 = 49.6 microM) showed the strongest and weakest inhibitory activity against AOX-catalyzed phenanthridine oxidation, respectively. benzaldehyde 15-27 acyl-CoA oxidase 1 Rattus norvegicus 365-368 30439624-3 2019 The biosensing approach implied the use of ITO electrode coated with poly(phosphazene) polymer including benzaldehyde groups attached with CDH22 antibody and CDH22 antigens. benzaldehyde 105-117 cadherin 22 Homo sapiens 139-144 30439624-4 2019 Benzaldehyde side groups containing poly(phosphazene) film coated disposable ITO electrode were utilized as an immunosensing platform and anti-CDH22 antibodies bound to aldehyde groups of benzaldehyde substituted poly(phosphazene) (P-PHP) covalently. benzaldehyde 0-12 cadherin 22 Homo sapiens 143-148 30439624-0 2019 Electrochemical immunosensor for CDH22 biomarker based on benzaldehyde substituted poly(phosphazene) modified disposable ITO electrode: A new fabrication strategy for biosensors. benzaldehyde 58-70 cadherin 22 Homo sapiens 33-38 30439624-4 2019 Benzaldehyde side groups containing poly(phosphazene) film coated disposable ITO electrode were utilized as an immunosensing platform and anti-CDH22 antibodies bound to aldehyde groups of benzaldehyde substituted poly(phosphazene) (P-PHP) covalently. benzaldehyde 188-200 cadherin 22 Homo sapiens 143-148 30362188-5 2018 Consequently, mutants that lack gcy-28 do not approach AWCON -sensed odors and cannot associate benzaldehyde with starvation. benzaldehyde 96-108 Receptor-type guanylate cyclase gcy-28 Caenorhabditis elegans 32-38 29253950-1 2018 The preparation, characterisation and application of two pyridine-modified chitosan derivatives (C1 and C2) containing Cu(OAc)2 adsorbed as catalysts for the conversion of benzaldehyde into 2-nitro-1-phenylethanol are described. benzaldehyde 172-184 heterogeneous nuclear ribonucleoprotein C Homo sapiens 97-127 29482386-3 2018 NVP BEZ-235 (BEZ) is a dual PI3K/mTOR inhibitor that has substantial anticancer effects. benzaldehyde 4-7 mechanistic target of rapamycin kinase Homo sapiens 33-37 29042337-10 2018 Cell functional assays, including migration assay and phosphowestern blot analysis of the mTOR and pI3K signaling pathways, revealed that the E-selectin targeted nanoparticles loaded with BEZ had a pronounced effect on inflammation-activated endothelial cells as compared to the non-targeted BEZ-loaded nanoparticles. benzaldehyde 188-191 mechanistic target of rapamycin kinase Homo sapiens 90-94 29042337-10 2018 Cell functional assays, including migration assay and phosphowestern blot analysis of the mTOR and pI3K signaling pathways, revealed that the E-selectin targeted nanoparticles loaded with BEZ had a pronounced effect on inflammation-activated endothelial cells as compared to the non-targeted BEZ-loaded nanoparticles. benzaldehyde 188-191 selectin E Homo sapiens 142-152 29042337-10 2018 Cell functional assays, including migration assay and phosphowestern blot analysis of the mTOR and pI3K signaling pathways, revealed that the E-selectin targeted nanoparticles loaded with BEZ had a pronounced effect on inflammation-activated endothelial cells as compared to the non-targeted BEZ-loaded nanoparticles. benzaldehyde 292-295 selectin E Homo sapiens 142-152 29464839-3 2018 For aerobic alcohol oxidation, Pd1 /CeO2 shows extremely high catalytic activity with a TOF of 6739 h-1 and satisfactory selectivity (almost 100 % for benzaldehyde), while Pd6 /CeO2 is inactive, indicating that the true active species are single Pd atoms. benzaldehyde 151-163 programmed cell death 1 Homo sapiens 31-34 30362188-4 2018 Here, we offer a different interpretation and show that GCY-28 functions in distinct neurons to modulate two independent processes: naive attraction to AWCON -sensed odors in the AWCON neuron, and associative learning of benzaldehyde and starvation in the AIA interneurons. benzaldehyde 221-233 Receptor-type guanylate cyclase gcy-28 Caenorhabditis elegans 56-62 29256251-2 2018 A catalytic amount of aniline as a transient directing group was efficient for the ruthenium-catalyzed ortho-C(sp2)-H alkylation of benzaldehyde with maleimide. benzaldehyde 132-144 Sp2 transcription factor Homo sapiens 109-114 29502118-2 2018 The present study was designed to investigate the inhibitory effects and mechanisms of benzaldehyde, vanillin, muscone, and borneol on P-glycoprotein (P-gp). benzaldehyde 87-99 ATP binding cassette subfamily B member 1 Homo sapiens 135-149 29502118-7 2018 CONCLUSIONS: These data indicate that benzaldehyde, vanillin, muscone and borneol could effectively reverse multidrug resistance via inhibiting the P-gp function and expression pathway. benzaldehyde 38-50 ATP binding cassette subfamily B member 1 Homo sapiens 148-152 29502118-2 2018 The present study was designed to investigate the inhibitory effects and mechanisms of benzaldehyde, vanillin, muscone, and borneol on P-glycoprotein (P-gp). benzaldehyde 87-99 ATP binding cassette subfamily B member 1 Homo sapiens 151-155 29034432-3 2017 Herein, we report that an uncharacterized open reading frame YKL071W from S. cerevisiae encodes a novel "classical" short-chain dehydrogenase/reductase (SDR) protein with NADH-dependent enzymatic activities for reduction of furfural (FF), glycolaldehyde (GA), formaldehyde (FA), and benzaldehyde (BZA). benzaldehyde 283-295 short-chain dehydrogenase/reductase Saccharomyces cerevisiae S288C 116-151 29034432-3 2017 Herein, we report that an uncharacterized open reading frame YKL071W from S. cerevisiae encodes a novel "classical" short-chain dehydrogenase/reductase (SDR) protein with NADH-dependent enzymatic activities for reduction of furfural (FF), glycolaldehyde (GA), formaldehyde (FA), and benzaldehyde (BZA). benzaldehyde 283-295 short-chain dehydrogenase/reductase Saccharomyces cerevisiae S288C 153-156 29034432-3 2017 Herein, we report that an uncharacterized open reading frame YKL071W from S. cerevisiae encodes a novel "classical" short-chain dehydrogenase/reductase (SDR) protein with NADH-dependent enzymatic activities for reduction of furfural (FF), glycolaldehyde (GA), formaldehyde (FA), and benzaldehyde (BZA). benzaldehyde 297-300 short-chain dehydrogenase/reductase Saccharomyces cerevisiae S288C 116-151 29034432-3 2017 Herein, we report that an uncharacterized open reading frame YKL071W from S. cerevisiae encodes a novel "classical" short-chain dehydrogenase/reductase (SDR) protein with NADH-dependent enzymatic activities for reduction of furfural (FF), glycolaldehyde (GA), formaldehyde (FA), and benzaldehyde (BZA). benzaldehyde 297-300 short-chain dehydrogenase/reductase Saccharomyces cerevisiae S288C 153-156 28435458-3 2017 This nanocapsule was fabricated by encapsulating stealthy cross-linked poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) and benzaldehyde groups around the protein bovine serum albumin (BSA) followed by conjugation of doxorubicin (Dox) through a pH-responsive benzoic-imine bond. benzaldehyde 129-141 albumin Homo sapiens 175-188 28513914-3 2017 Proline and acid groups appended to catalytic fibers of two self-sorting hydrogelators compete for the Mannich reaction between aniline, benzaldehyde, and cyclohexanone to give low overall selectivity (anti/syn 77:23). benzaldehyde 137-149 synemin Homo sapiens 207-210 28456625-6 2017 In addition, a rather rare chlorinated benzaldehyde derivative, 3,5-dichloro-4-methoxybenzaldehyde isolated from the same source, was found to show potent cytotoxicity, and the chlorine atom reduced a tyrosinase inhibitory activity but enhanced cytotoxicity. benzaldehyde 39-51 tyrosinase Mus musculus 201-211 28006102-2 2017 Herein, we report a diverse set of ortho-C(sp2)-H functionalizations of benzaldehyde substrates using the transient directing group strategy. benzaldehyde 72-84 Sp2 transcription factor Homo sapiens 41-46 28125229-7 2017 Compound 2 showed a 94% conversion of benzaldehyde into (dimethoxymethyl)benzene after just 1 h of reaction, among the best results registered to date for MOF materials. benzaldehyde 38-50 lysine acetyltransferase 8 Homo sapiens 155-158 28126723-7 2017 Ald4p, on the contrary, showed activity with benzaldehyde along with a limited range of aliphatic aldehydes. benzaldehyde 45-57 aldehyde dehydrogenase (NADP(+)) ALD4 Saccharomyces cerevisiae S288C 0-5 28158265-6 2017 The most active compounds were conjugates of 3beta-O-acetylbetulinic acid and among them, conjugate with triazole substituted by benzaldehyde 9b was the best with IC50 of 3.3 muM and therapeutic index of 9.1. benzaldehyde 129-141 latexin Homo sapiens 175-178 27766585-8 2016 SSAO activity was higher in fat than in plasma, when expressed as radiolabeled benzaldehyde per milligram of protein. benzaldehyde 79-91 amine oxidase copper containing 3 Homo sapiens 0-4 28004102-7 2016 According to Langmuir model data, maximum adsorption capacities (qm) of Fez natural clay and zeolite toward methanol (M), toluene (T) and benzaldehyde (B) at 300 K are 8, 0.89 and 3.1 mmol g-1, and 15, 1.91 and 13.9 mmol g-1 respectively. benzaldehyde 138-150 FEZ family zinc finger 1 Homo sapiens 72-75 27844007-0 2015 A theoretical study of benzaldehyde derivatives as tyrosinase inhibitors using Ab initio calculated NQCC parameters. benzaldehyde 23-35 tyrosinase Homo sapiens 51-61 26538114-4 2015 Co(II) catalysed galvanostatic electrolysis of toluene at room temperature has shown that benzaldehyde was formed along with a small quantity of 3-methyl-1-hexanol. benzaldehyde 90-102 mitochondrially encoded cytochrome c oxidase II Homo sapiens 0-6 29899938-3 2016 This benzaldehyde-mediated photoredox reaction proceeded smoothly with household 23 W CFL bulbs as the energy source under metal-free conditions, allowing the construction of new Csp2 -Csp2 and Csp3 -Csp2 bonds and access to important pharmacophores of broad utility using commercially available reagents. benzaldehyde 5-17 regulator of calcineurin 2 Homo sapiens 179-183 29899938-3 2016 This benzaldehyde-mediated photoredox reaction proceeded smoothly with household 23 W CFL bulbs as the energy source under metal-free conditions, allowing the construction of new Csp2 -Csp2 and Csp3 -Csp2 bonds and access to important pharmacophores of broad utility using commercially available reagents. benzaldehyde 5-17 regulator of calcineurin 2 Homo sapiens 185-189 29899938-3 2016 This benzaldehyde-mediated photoredox reaction proceeded smoothly with household 23 W CFL bulbs as the energy source under metal-free conditions, allowing the construction of new Csp2 -Csp2 and Csp3 -Csp2 bonds and access to important pharmacophores of broad utility using commercially available reagents. benzaldehyde 5-17 regulator of calcineurin 2 Homo sapiens 185-189 27844007-2 2015 It can catalyze two distinct reactions of melanin synthesis and benzaldehyde derivatives, which are potential tyrosinase inhibitors. benzaldehyde 64-76 tyrosinase Homo sapiens 110-120 25512087-4 2015 We found that DEAB is an excellent substrate for ALDH3A1, exhibiting a Vmax/KM that exceeds that of its commonly used substrate, benzaldehyde. benzaldehyde 129-141 aldehyde dehydrogenase 3 family member A1 Homo sapiens 49-56 26041530-0 2015 Determination of human serum semicarbazide-sensitive amine oxidase activity via flow injection analysis with fluorescence detection after online derivatization of the enzymatically produced benzaldehyde with 1,2-diaminoanthraquinone. benzaldehyde 190-202 amine oxidase copper containing 2 Homo sapiens 29-66 26041530-2 2015 Benzaldehyde, generated by the action of SSAO after incubation of serum with benzylamine, was derivatized with a novel aromatic aldehyde-specific reagent (1,2-diaminoanthraquinone) and the fluorescent product was measured by fluorescence detection at excitation and emission wavelengths of 390 and 570nm, respectively. benzaldehyde 0-12 amine oxidase copper containing 2 Homo sapiens 41-45 26041530-2 2015 Benzaldehyde, generated by the action of SSAO after incubation of serum with benzylamine, was derivatized with a novel aromatic aldehyde-specific reagent (1,2-diaminoanthraquinone) and the fluorescent product was measured by fluorescence detection at excitation and emission wavelengths of 390 and 570nm, respectively. benzaldehyde 119-136 amine oxidase copper containing 2 Homo sapiens 41-45 26041530-3 2015 Serum SSAO activity was defined as benzaldehyde (nmol) formed per milliliter serum per hour. benzaldehyde 35-47 amine oxidase copper containing 2 Homo sapiens 6-10 24928349-8 2014 Activation of P2X1 receptors had more profound inhibitory effects on benzaldehyde-evoked intracellular calcium elevation than on acetophenone-evoked responses within the same neurons, and the reverse was true when P2Y2 receptors were activated. benzaldehyde 69-81 purinergic receptor P2X 1 Homo sapiens 14-18 25587431-1 2014 Biosensors for the detection of benzaldehyde and gamma-aminobutyric acid (GABA) are reported using aldehyde oxidoreductase PaoABC from Escherichia coli immobilized in a polymer containing bound low potential osmium redox complexes. benzaldehyde 32-44 oxidoreductase Escherichia coli 108-122 25107441-5 2014 These results imply that oral benzaldehyde exerts antiallergic effects in murine allergic asthma and rhinitis, possibly through inhibition of HIF-1alpha and VEGF. benzaldehyde 30-42 hypoxia inducible factor 1, alpha subunit Mus musculus 142-152 25107441-5 2014 These results imply that oral benzaldehyde exerts antiallergic effects in murine allergic asthma and rhinitis, possibly through inhibition of HIF-1alpha and VEGF. benzaldehyde 30-42 vascular endothelial growth factor A Mus musculus 157-161 25050912-5 2014 Thus, benzaldehyde reacts with 6 to give the [2 + 2] cycloaddition product 7, while 4-bromoacetophenone reacts via C-H bond cleavage and formation of the enolate Cp*(IXy)(H)2RuSiH[OC( CH2)C6H4Br]Trip (8). benzaldehyde 6-18 TRAF interacting protein Homo sapiens 195-199 24853908-2 2014 METHODS: Plasma SSAO activity in 94 type 1 diabetes (T1DM) patients, including 34 with microvascular complications T1DM CX[+], and in 96 healthy subjects (CON) was measured by production of benzaldehyde using high-performance liquid chromatography (HPLC). benzaldehyde 190-202 amine oxidase copper containing 3 Homo sapiens 16-20 25122208-6 2014 Our results indicated that increased CG11699 expression leads to xenobiotic stress resistance through increased ALDH-III activity: flies with FBti0019627 insertion showed increased survival rate in response to benzaldehyde, a natural xenobiotic, and to carbofuran, a synthetic insecticide. benzaldehyde 210-222 uncharacterized protein Drosophila melanogaster 37-44 25122208-6 2014 Our results indicated that increased CG11699 expression leads to xenobiotic stress resistance through increased ALDH-III activity: flies with FBti0019627 insertion showed increased survival rate in response to benzaldehyde, a natural xenobiotic, and to carbofuran, a synthetic insecticide. benzaldehyde 210-222 Aldehyde dehydrogenase type III Drosophila melanogaster 112-120 25028006-4 2014 Finally, we also validate our approach empirically by analyzing the behavior of the derivative couplings around the T1/T2 conical intersection of benzaldehyde. benzaldehyde 146-158 interleukin 1 receptor like 1 Homo sapiens 116-121 24358880-9 2013 TRPV1 knockouts showed deficiencies in the detection of benzaldehyde, cyclohexanone and eugenol in at least one assay. benzaldehyde 56-68 transient receptor potential cation channel, subfamily V, member 1 Mus musculus 0-5 23551266-1 2013 Treatment of benzaldehyde and an acetoacetate ester with potassium carbonate in an alcohol solvent proceeds via gamma-C-alkylation rather than alpha-C-alkylation resulting in the formation of 6-phenyl-2,4-dioxotetrahydropyran. benzaldehyde 13-25 interleukin 2 receptor subunit gamma Homo sapiens 112-119 23914541-3 2013 The health risks of PCO of toluene and benzaldehyde were assessed based on health risk influence index (eta). benzaldehyde 39-51 endothelin receptor type A Homo sapiens 104-107 24061865-1 2013 PURPOSE: Benzaldehyde dimethane sulfonate (DMS612, NSC281612, BEN) is an alkylator with activity against renal cell carcinoma, currently in phase I trials. benzaldehyde 9-21 general transcription factor II I repeat domain-containing 1 Mus musculus 62-65 23914541-7 2013 In the PCO process of toluene and benzaldehyde, eta reached the maximum values of 8 499.68 and 21.43, with the eta(VAs), contribution of VAs to the health risk influence index of outlet, reaching 99.3% and 98.3%, respectively. benzaldehyde 34-46 endothelin receptor type A Homo sapiens 48-51 23914541-7 2013 In the PCO process of toluene and benzaldehyde, eta reached the maximum values of 8 499.68 and 21.43, with the eta(VAs), contribution of VAs to the health risk influence index of outlet, reaching 99.3% and 98.3%, respectively. benzaldehyde 34-46 endothelin receptor type A Homo sapiens 111-114 23914541-9 2013 When PCO of toluene and benzaldehyde reached steady state, eta were 236.09 and 2.30, and eta(VAs) reached 97.9% and 97.8%, respectively. benzaldehyde 24-36 endothelin receptor type A Homo sapiens 59-62 23285706-10 2012 Kinetic parameters (Km, Vmax) of recombinant ALDH1A1 towards several aliphatic and aromatic aldehydes occurring in food products (vanillin, citral, furfural, cinnamaldehyde, anisaldehyde, benzaldehyde and trans-hexenal) were determined by measuring the increase of NADH fluorescence after adding various concentrations of aldehyde substrates. benzaldehyde 188-200 aldehyde dehydrogenase 1 family member A1 Homo sapiens 45-52 22051410-2 2012 The density functional theory (DFT) B3LYP/6-31G* method was chosen to calculate the infrared spectrum of benzaldehyde in gaseous state. benzaldehyde 105-117 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 38-41 22279051-3 2012 AO has an important role in the metabolism of drugs based on its broad substrate specificity oxidizing aromatic aza-heterocycles, for example, N(1)-methylnicotinamide and N-methylphthalazinium, or aldehydes, such as benzaldehyde, retinal, and vanillin. benzaldehyde 216-228 aldehyde oxidase 1 Homo sapiens 0-2 22154910-8 2012 The superior photocatalytic activity of SiO(2)@CdS composites for the benzaldehyde oxidation under UV irradiation has been displayed. benzaldehyde 70-82 CDP-diacylglycerol synthase 1 Homo sapiens 47-50 21893110-0 2011 Ultra-high olfactory sensitivity for the human sperm-attractant aromatic aldehyde bourgeonal in CD-1 mice. benzaldehyde 64-81 CD1c molecule Homo sapiens 96-100 23209525-3 2012 The relative configuration of a new isomer of tropinone aldol accessible synthetically through the direct solventless reaction of tropinone and benzaldehyde in the presence of water was determined as exo,syn by comparison of NMR data of the aldol isomers, in particular vicinal coupling constants and shifts corresponding to the side-chain CH group, with data of related TBDMS derivatives and confirmed by single-crystal X-ray diffraction. benzaldehyde 144-156 synemin Homo sapiens 73-76 21414430-6 2011 The metabolites of BZA or MA catalyzed by SSAO, hydrogen peroxide, formaldehyde, and benzaldehyde could also significantly decrease LPS-induced nitric oxide and TNF-alpha production, iNOS and COX-2 expression, and glucose consumption in vitro. benzaldehyde 85-97 tumor necrosis factor Mus musculus 161-170 21705476-1 2011 Aldehyde oxidase (AOX) is characterized by a broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, or aldehydes, such as benzaldehyde, retinal, and vanillin. benzaldehyde 189-201 acyl-Coenzyme A oxidase 1, palmitoyl Mus musculus 0-16 21705476-1 2011 Aldehyde oxidase (AOX) is characterized by a broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, or aldehydes, such as benzaldehyde, retinal, and vanillin. benzaldehyde 189-201 acyl-Coenzyme A oxidase 1, palmitoyl Mus musculus 18-21 21414430-6 2011 The metabolites of BZA or MA catalyzed by SSAO, hydrogen peroxide, formaldehyde, and benzaldehyde could also significantly decrease LPS-induced nitric oxide and TNF-alpha production, iNOS and COX-2 expression, and glucose consumption in vitro. benzaldehyde 85-97 nitric oxide synthase 2, inducible Mus musculus 183-187 21414430-6 2011 The metabolites of BZA or MA catalyzed by SSAO, hydrogen peroxide, formaldehyde, and benzaldehyde could also significantly decrease LPS-induced nitric oxide and TNF-alpha production, iNOS and COX-2 expression, and glucose consumption in vitro. benzaldehyde 85-97 cytochrome c oxidase II, mitochondrial Mus musculus 192-197 21508382-6 2011 RESULTS: The sulfated chitosan (SCS) and the sulfated benzaldehyde chitosan (SBCS) significantly inhibited cell proliferation, induced apoptosis and blocked the FGF-2-induced phosphorylation of ERK in MCF-7 cells, SBCS had better inhibitory effects and a lower IC(50) compared to SCS. benzaldehyde 54-66 fibroblast growth factor 2 Homo sapiens 161-166 20699116-5 2010 ALDH3B1 demonstrated high affinity for hexanal (K(m)=62 muM), octanal (K(m)=8 muM), 4-hydroxy-2-nonenal (4HNE; K(m)=52 muM), and benzaldehyde (K(m)=46 muM). benzaldehyde 129-141 aldehyde dehydrogenase 3 family member B1 Homo sapiens 0-7 21508382-6 2011 RESULTS: The sulfated chitosan (SCS) and the sulfated benzaldehyde chitosan (SBCS) significantly inhibited cell proliferation, induced apoptosis and blocked the FGF-2-induced phosphorylation of ERK in MCF-7 cells, SBCS had better inhibitory effects and a lower IC(50) compared to SCS. benzaldehyde 54-66 mitogen-activated protein kinase 1 Homo sapiens 194-197 21308960-6 2011 Benzaldehyde (9 microg mL(-1) ) was the most toxic compound, followed by gamma-eudesmol (50 microg mL(-1) ) and estragole (180 microg mL(-1) ), based on 96 h EC(50) values. benzaldehyde 0-12 L1 cell adhesion molecule Mus musculus 23-29 20833259-7 2010 Kvbeta2 was found to catalyse the reduction of aromatic aldehyde substrates such as 2, 3 and 4-nitrobenzaldehydes, 4-hydroxybenzaldehyde, pyridine 2-aldehyde and benzaldehyde. benzaldehyde 47-64 potassium voltage-gated channel subfamily A regulatory beta subunit 2 Homo sapiens 0-7 20833259-7 2010 Kvbeta2 was found to catalyse the reduction of aromatic aldehyde substrates such as 2, 3 and 4-nitrobenzaldehydes, 4-hydroxybenzaldehyde, pyridine 2-aldehyde and benzaldehyde. benzaldehyde 100-112 potassium voltage-gated channel subfamily A regulatory beta subunit 2 Homo sapiens 0-7 20835425-1 2010 Transketolase mutants have been identified that accept aromatic acceptors with good stereoselectivities, in particular benzaldehyde for which the wild type enzyme showed no activity. benzaldehyde 119-131 transketolase Homo sapiens 0-13 21043489-2 2010 By combining the surface basicity and semiconductor functions of mpg-C(3)N(4), the photocatalytic system can realize a high catalytic selectivity to generate benzaldehyde. benzaldehyde 158-170 N-methylpurine DNA glycosylase Homo sapiens 65-68 20503998-1 2010 The origin of stereoselective formation of Evans syn and non-Evans anti aldol products in the reaction between titanium enolate derived from N-succinyloxazolidinone and benzaldehyde is established by using transition-state modeling. benzaldehyde 169-181 synemin Homo sapiens 49-52 20628035-5 2010 We identified polymorphisms in Or10a, Or43a, and Or67b that were significantly associated with variation in response to benzaldehyde. benzaldehyde 120-132 Odorant receptor 10a Drosophila melanogaster 31-36 20628035-5 2010 We identified polymorphisms in Or10a, Or43a, and Or67b that were significantly associated with variation in response to benzaldehyde. benzaldehyde 120-132 Odorant receptor 43a Drosophila melanogaster 38-43 20628035-5 2010 We identified polymorphisms in Or10a, Or43a, and Or67b that were significantly associated with variation in response to benzaldehyde. benzaldehyde 120-132 Odorant receptor 67b Drosophila melanogaster 49-54 20628035-9 2010 We also observed a correspondence between behavioral response to benzaldehyde and differences in Or10a and Or43a expression. benzaldehyde 65-77 Odorant receptor 10a Drosophila melanogaster 97-102 20628035-9 2010 We also observed a correspondence between behavioral response to benzaldehyde and differences in Or10a and Or43a expression. benzaldehyde 65-77 Odorant receptor 43a Drosophila melanogaster 107-112 20432412-0 2010 Synthesis of benzaldehyde-functionalized glycans: a novel approach towards glyco-SAMs as a tool for surface plasmon resonance studies. benzaldehyde 13-25 methionine adenosyltransferase 1A Homo sapiens 81-85 19936267-5 2009 In the course of this study, an L-asparagine derivative was condensed with benzaldehyde and subsequently converted to orthogonally protected (R)-beta(2)-homoaspartate. benzaldehyde 75-87 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 145-151 20378596-1 2010 Recent studies have shown that sperm chemotaxis critically involves the human olfactory receptor OR1D2, which is activated by the aromatic aldehyde bourgeonal. benzaldehyde 130-147 olfactory receptor family 1 subfamily D member 2 Homo sapiens 97-102 20045461-2 2010 In mammals, benzylamine is metabolized by semicarbazide-sensitive amine oxidase (SSAO) to benzaldehyde and hydrogen peroxide. benzaldehyde 90-102 amine oxidase, copper containing 3 Mus musculus 42-79 20045461-2 2010 In mammals, benzylamine is metabolized by semicarbazide-sensitive amine oxidase (SSAO) to benzaldehyde and hydrogen peroxide. benzaldehyde 90-102 amine oxidase, copper containing 3 Mus musculus 81-85 19945871-2 2010 SAR studies, by varying the substituted benzaldehyde components, lead to the discovery of a series of potent JAK2 kinase inhibitors. benzaldehyde 40-52 Janus kinase 2 Homo sapiens 109-113 20042251-8 2010 Benzaldehyde-functionalized glycosides of mono and disaccharides were synthesized by metathesis and could be used for the formation of novel glyco-self assembled monolayers (glyco-SAMs) employing various tether structures and attached to gold surfaces. benzaldehyde 0-12 methionine adenosyltransferase 1A Homo sapiens 180-184 20534848-2 2010 Here, we show that insulin signaling also is required in benzaldehyde-starvation associative plasticity, in which worms pre-exposed to the odor attractant benzaldehyde in the absence of food subsequently demonstrate a conditioned aversion response toward the odorant. benzaldehyde 57-69 insulin Homo sapiens 19-26 20534848-2 2010 Here, we show that insulin signaling also is required in benzaldehyde-starvation associative plasticity, in which worms pre-exposed to the odor attractant benzaldehyde in the absence of food subsequently demonstrate a conditioned aversion response toward the odorant. benzaldehyde 155-167 insulin Homo sapiens 19-26 20534848-3 2010 Animals with mutations in insulin-related 1 (ins-1), abnormal dauer formation 2 (daf-2), and aging alteration 1 (age-1), which encode the homolog of human insulin, insulin/IGF-1 receptor, and PIP3 kinase, respectively, demonstrated significant deficits in benzaldehyde-starvation associative plasticity. benzaldehyde 256-268 insulin Homo sapiens 155-186 19156319-3 2009 Furthermore, the aldol reaction of the lithium enolate of cis-2-ferrocenyl-3-pivaloyl-4-methyl-1,3-oxazolidin-5-one with benzaldehyde followed by in situ O-protection affords O-protected aldol products in >98% de, with hydrolysis affording (2R,3S)-2-amino-2-methyl-3-hydroxy-3-phenylpropanoic acid in >98% de. benzaldehyde 121-133 suppressor of cytokine signaling 2 Homo sapiens 58-63 19297586-0 2009 An aldehyde oxidase in developing seeds of Arabidopsis converts benzaldehyde to benzoic Acid. benzaldehyde 64-76 aldehyde oxidase 1 Arabidopsis thaliana 3-19 18983993-15 2009 Yeast ALDH2 exhibited K(M) for straight-chain aliphatic aldehydes (C1-C10), 2.3-210 microM, and substrate inhibition constants (C2-C10), 79-2900 microM, with a trend of being smaller K(M) and K(i) for longer chain lengths; and K(M) for cinnamaldehyde, benzaldehyde, and 2-furaldehyde, 5.0, 79, and 1000 microM, respectively. benzaldehyde 252-264 aldehyde dehydrogenase 2 family member Homo sapiens 6-11 19730689-4 2009 We demonstrate that the inositol 1,4,5-trisphosphate receptor (IP(3)R), encoded by itr-1, functions in the reversal responses to nose touch and benzaldehyde, but not in other known ASH-mediated responses. benzaldehyde 144-156 Inositol 1,4,5-trisphosphate receptor itr-1 Caenorhabditis elegans 83-88 19200549-7 2009 A cyclohexyldiol-silica fiber was used, as a simple example of applicability, for the successful determination of benzaldehyde, acetophenone and dimethylphenol at trace level in spiked tap water. benzaldehyde 114-126 nuclear RNA export factor 1 Homo sapiens 185-188 19100833-7 2009 BmOR19 responds to linalool, while BmOR45 and BmOR47 respond to benzoic acid > 2-phenylethanol > benzaldehyde. benzaldehyde 103-115 olfactory receptor 45 Bombyx mori 35-41 19100833-7 2009 BmOR19 responds to linalool, while BmOR45 and BmOR47 respond to benzoic acid > 2-phenylethanol > benzaldehyde. benzaldehyde 103-115 olfactory receptor 47 Bombyx mori 46-52 18522428-1 2008 Theoretical simulation on the enantioselective cyanation of benzaldehyde over titanium-salicylaldehyde catalysts is performed with B3LYP//ONIOM methods. benzaldehyde 60-72 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 133-136 18984566-4 2008 This delayed avoidance is due to an increased attraction rather than a decreased avoidance to benzaldehyde because (1) aged odr-3 mutants that are defective in odor attraction showed no delayed benzaldehyde avoidance, and (2) the delay in avoidance was also observed with another attractant diacetyl, but not the repellent octanol. benzaldehyde 94-106 Guanine nucleotide-binding protein alpha-17 subunit Caenorhabditis elegans 124-129 18186090-4 2008 Analysis by solid-phase catalysis/circular dichroism high-throughput screening of a copper-catalyzed Henry reaction revealed that ligand L25, comprising a (S,S)-diphenylethylenediamine-derived imidazoline, (S)-phenylethylamine, and dibromophenol, was highly efficient, thus providing the adduct of nitromethane and benzaldehyde in 95 % ee. benzaldehyde 315-327 immunoglobulin kappa variable 3D-7 Homo sapiens 137-140 21202829-3 2008 The title product resulted from a three-component reaction of benzaldehyde, 1-ethynylbenzene and p-toluidine via C-H activation of 1-ethynylbenzene catalyzed by CuI in the ionic liquid 1-butyl-3-methyl-imidazolium hexa-fluoro-phosphate. benzaldehyde 62-74 hexosaminidase subunit alpha Homo sapiens 214-218 18154299-2 2008 A 80% de in favor of the anti product has been experimentally observed with both saturated aldehydes, while for benzaldehyde, a 1:1 syn/anti ratio has been found. benzaldehyde 112-124 synemin Homo sapiens 132-135 18154299-5 2008 The computational investigation of the reaction of these allylic organozinc complexes with benzaldehyde and 2-methylpropanal demonstrates in both cases the existence of two competitive reaction paths leading to the syn and anti adducts, respectively. benzaldehyde 91-103 synemin Homo sapiens 215-218 17867698-1 2007 syn-beta-Hydroxyallylsilanes of general structure 11 and 28 are prepared in 50-86% yield and 91-95% ee (for aliphatic aldehydes; 50% ee for benzaldehyde) via the BF(3).Et(2)O-promoted gamma-silylallylboration reactions, using reagents 14 and 15. benzaldehyde 140-152 synemin Homo sapiens 0-3 19148285-1 2008 The palladium (II) bis-chelate Pd (L(1-3))(2) and platinum (II) tetranuclear Pt(4)(L(4))(4) complexes of benzaldehyde thiosemicarbazone derivatives have been synthesized, and characterized by elemental analysis and IR, FAB(+)-mass and NMR ((1)H, (13)C) spectroscopy. benzaldehyde 105-117 FA complementation group B Homo sapiens 219-222 18061070-5 2007 The ALDH-2 activity and expression in these segments were assessed by the conversion of a benzaldehyde or its derivative to the benzoic acid metabolite and by Western blotting technique. benzaldehyde 90-102 aldehyde dehydrogenase 2 family member Homo sapiens 4-10 17720903-6 2007 Four polymorphisms in 3 Obp genes exceeded the statistical permutation threshold for association with responsiveness to benzaldehyde, suggesting redundancy and/or combinatorial recognition by these OBPs of this odorant. benzaldehyde 120-132 Optix-binding protein Drosophila melanogaster 24-27 17382292-5 2007 Human ALDH3B1 was baculovirus-expressed and found to be catalytically active towards medium- and long-chain aliphatic aldehydes and the aromatic aldehyde benzaldehyde. benzaldehyde 136-153 aldehyde dehydrogenase 3 family member B1 Homo sapiens 6-13 17435226-3 2007 To begin to address this problem, we used olfactory behavior in Drosophila melanogaster as a model and showed that a hypomorphic transposon-mediated mutation of the early developmental gene Semaphorin-5c (Sema-5c) results in aberrant behavioral responses to the repellant odorant benzaldehyde. benzaldehyde 280-292 Semaphorin 5c Drosophila melanogaster 190-203 17435226-3 2007 To begin to address this problem, we used olfactory behavior in Drosophila melanogaster as a model and showed that a hypomorphic transposon-mediated mutation of the early developmental gene Semaphorin-5c (Sema-5c) results in aberrant behavioral responses to the repellant odorant benzaldehyde. benzaldehyde 280-292 Semaphorin 5c Drosophila melanogaster 205-212 17382292-5 2007 Human ALDH3B1 was baculovirus-expressed and found to be catalytically active towards medium- and long-chain aliphatic aldehydes and the aromatic aldehyde benzaldehyde. benzaldehyde 154-166 aldehyde dehydrogenase 3 family member B1 Homo sapiens 6-13 17249797-1 2007 [reaction: see text] The alcohol-catalyzed Diels-Alder reactions of acrolein and benzaldehyde with Rawal"s diene were evaluated with density functional theory (B3LYP/6-31G(d)). benzaldehyde 81-93 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 162-165 17318518-2 2007 The functional sensing surface was fabricated by the immobilization of a benzaldehyde-ovalbumin conjugate (BZ-OVA) on Au-thiolate SAMs containing carboxyl end groups. benzaldehyde 73-85 methionine adenosyltransferase 1A Homo sapiens 130-134 16354669-6 2006 PAO supplemented with benzaldehyde predominantly catalyzed the cleavage of (R)-isomer of alpha-methylspermidine, whereas in the presence of pyridoxal the (S)-alpha-methylspermidine was preferred. benzaldehyde 22-34 polyamine oxidase Homo sapiens 0-3 16802822-3 2006 The reaction proceeds smoothly at room temperature in the absence of any phosphane or nitrogen ligands and is highly regioselective and stereoselective for a wide variety combination of aldehydes and 1,3-dienes: e.g., isoprene and benzaldehyde combine to give a mixture of anti- and syn-1-phenyl-3-methyl-4-penten-1-ol (2.2) in a ratio of 15:1 in 90% yield. benzaldehyde 231-243 synapsin I Homo sapiens 283-288 15958189-1 2005 Acetohydroxy acid synthase (AHAS) and related enzymes catalyze the production of chiral compounds [(S)-acetolactate, (S)-acetohydroxybutyrate, or (R)-phenylacetylcarbinol] from achiral substrates (pyruvate, 2-ketobutyrate, or benzaldehyde). benzaldehyde 226-238 ilvB acetolactate synthase like Homo sapiens 0-26 16441137-1 2006 The benzaldehyde thiosemicarbazones are found to undergo oxidation at the sulfur center upon reaction with [Rh(PPh3)3Cl] in refluxing ethanol in the presence of a base (NEt3). benzaldehyde 4-16 protein phosphatase 4 catalytic subunit Homo sapiens 111-115 16441137-1 2006 The benzaldehyde thiosemicarbazones are found to undergo oxidation at the sulfur center upon reaction with [Rh(PPh3)3Cl] in refluxing ethanol in the presence of a base (NEt3). benzaldehyde 4-16 tetraspanin 2 Homo sapiens 169-173 16441137-4 2006 Reaction of the benzaldehyde thiosemicarbazones with [Rh(PPh3)3Cl] in refluxing ethanol in the absence of NEt3 affords another group of organorhodium complexes, in which the thiosemicarbazones are coordinated to rhodium as tridentate CNS donors, along with two triphenylphosphines and a chloride. benzaldehyde 16-28 protein phosphatase 4 catalytic subunit Homo sapiens 57-61 16188506-3 2005 SSAO activity can be quantified by assaying benzaldehyde production using fluorescent derivatisation and separation by HPLC. benzaldehyde 44-56 amine oxidase copper containing 2 Homo sapiens 0-4 15958189-1 2005 Acetohydroxy acid synthase (AHAS) and related enzymes catalyze the production of chiral compounds [(S)-acetolactate, (S)-acetohydroxybutyrate, or (R)-phenylacetylcarbinol] from achiral substrates (pyruvate, 2-ketobutyrate, or benzaldehyde). benzaldehyde 226-238 ilvB acetolactate synthase like Homo sapiens 28-32 15380725-7 2004 SSAO enzyme activity is defined as benzaldehyde (nmol) formed per ml plasma per hour. benzaldehyde 35-47 amine oxidase copper containing 2 Homo sapiens 0-4 16833774-0 2005 Hydrogenation of benzaldehyde and cinnamaldehyde in compressed CO2 medium with a Pt/C catalyst: a study on molecular interactions and pressure effects. benzaldehyde 17-29 complement C2 Homo sapiens 63-66 15720138-5 2005 First, classical AOX electron donor substrates (benzaldehyde, 2-hydroxypyrimidine, and N-methylnicotinamide) dramatically increase the rate of formation of IMI metabolites. benzaldehyde 48-60 aldehyde oxidase 1 Homo sapiens 17-20 15647466-0 2005 An increased receptive field of olfactory receptor Or43a in the antennal lobe of Drosophila reduces benzaldehyde-driven avoidance behavior. benzaldehyde 100-112 Odorant receptor 43a Drosophila melanogaster 51-56 15647466-3 2005 The behavioral response of GH320/UAS-or43a flies was changed upon benzaldehyde application. benzaldehyde 66-78 Odorant receptor 43a Drosophila melanogaster 37-42 15647466-6 2005 We therefore conclude that the application of benzaldehyde, an identified ligand of Or43a, resulted in activation of a number of glomeruli in transformed flies in addition to glomerulus DA4, which is the regular target of Or43a expressing neurons. benzaldehyde 46-58 Odorant receptor 43a Drosophila melanogaster 84-89 15647466-6 2005 We therefore conclude that the application of benzaldehyde, an identified ligand of Or43a, resulted in activation of a number of glomeruli in transformed flies in addition to glomerulus DA4, which is the regular target of Or43a expressing neurons. benzaldehyde 46-58 Odorant receptor 43a Drosophila melanogaster 222-227 15390260-2 2004 We have utilized molecular mechanics (MM) simulations, in conjunction with new force field parameters for aldehydes, to study the atomic details of benzaldehyde binding to ALDH3A1. benzaldehyde 148-160 aldehyde dehydrogenase 3 family member A1 Homo sapiens 172-179 15390260-4 2004 The negatively charged Cys243 (thiolate form) of ALDH3A1 also binds benzaldehyde in a stable conformation but in this complex the sulfur of Cys243 is oriented away from benzaldehyde yet yields the most favorable MM-GBMV complexation energy. benzaldehyde 68-80 aldehyde dehydrogenase 3 family member A1 Homo sapiens 49-56 15390260-4 2004 The negatively charged Cys243 (thiolate form) of ALDH3A1 also binds benzaldehyde in a stable conformation but in this complex the sulfur of Cys243 is oriented away from benzaldehyde yet yields the most favorable MM-GBMV complexation energy. benzaldehyde 169-181 aldehyde dehydrogenase 3 family member A1 Homo sapiens 49-56 15200326-2 2004 The enolate can be protonated to yield the corresponding ketone or treated with benzaldehyde to give the aldol product with good syn or anti diastereoselectivity depending on the conditions. benzaldehyde 80-92 synemin Homo sapiens 129-132 15255735-5 2004 Another distinct behavior between the Ni- and Pd-catalyzed allylation was demonstrated in the reaction of hex-1,5-diene-3,4-diol derivatives: the Pd catalyst did not give any coupling product, whereas the Ni-catalyzed InI-mediated reaction with benzaldehyde afforded the 1:1 and 1:2 adduct diols selectively depending on the reaction conditions. benzaldehyde 245-257 exonuclease 1 Homo sapiens 106-111 15255735-5 2004 Another distinct behavior between the Ni- and Pd-catalyzed allylation was demonstrated in the reaction of hex-1,5-diene-3,4-diol derivatives: the Pd catalyst did not give any coupling product, whereas the Ni-catalyzed InI-mediated reaction with benzaldehyde afforded the 1:1 and 1:2 adduct diols selectively depending on the reaction conditions. benzaldehyde 245-257 PHD finger protein 5A Homo sapiens 218-221 14510556-5 2003 This ligand (10 mol %) catalyzed the addition of Me2Zn to 2-naphthaldehyde, benzaldehyde, and 4-chlorobenzaldehyde to give the corresponding alcohol products in 86%, 84% and 81% ee, respectively. benzaldehyde 76-88 malic enzyme 2 Homo sapiens 49-52 15087594-5 2004 Toluene and phenol, which compose cigarette smoke, and benzaldehyde stimulated MMP-1 and/or elastin expression. benzaldehyde 55-67 matrix metallopeptidase 1 Homo sapiens 79-84 15087594-5 2004 Toluene and phenol, which compose cigarette smoke, and benzaldehyde stimulated MMP-1 and/or elastin expression. benzaldehyde 55-67 elastin Homo sapiens 92-99 15087594-7 2004 Toluene, benzaldehyde and phenol can directly cause facial wrinkling and impaired structural integrity by upregulating MMP-1 and/or elastin. benzaldehyde 9-21 matrix metallopeptidase 1 Homo sapiens 119-124 15087594-7 2004 Toluene, benzaldehyde and phenol can directly cause facial wrinkling and impaired structural integrity by upregulating MMP-1 and/or elastin. benzaldehyde 9-21 elastin Homo sapiens 132-139 12693212-11 2003 of 6b with acetone forms the methyl enolate complex [Ru2(trpy)2(6,6"-Me2dppz)(CH2COCH3)](PF6)2 (9b) while, analogously to a Cannizarro reaction, the reaction with benzaldehyde forms the bridging benzoate complex [Ru2(trpy)2(6,6"-Me2dppz)(C6H4CO2)](PF6)2 (11b). benzaldehyde 163-175 sperm associated antigen 17 Homo sapiens 89-92 12767028-8 2003 Sensory input to DL2 and, to a minor extent, VM1 and/or VM4, appear to be required for benzaldehyde perception, while acetone is processed through DL1. benzaldehyde 87-99 lectin-37Da Drosophila melanogaster 17-20 12767028-8 2003 Sensory input to DL2 and, to a minor extent, VM1 and/or VM4, appear to be required for benzaldehyde perception, while acetone is processed through DL1. benzaldehyde 87-99 vm1 Drosophila melanogaster 45-48 12767029-8 2003 Exposure to benzaldehyde at days 2-5 of adult life, but not at 8-11, causes behavioral adaptation as well as structural changes in DM2 and V glomeruli. benzaldehyde 12-24 tarsal-less 2A Drosophila melanogaster 131-134 12746108-0 2003 More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde. benzaldehyde 114-126 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 32-38 12746108-0 2003 More potent inhibition of human CYP2A6 than mouse CYP2A5 enzyme activities by derivatives of phenylethylamine and benzaldehyde. benzaldehyde 114-126 cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus 50-56 12746108-4 2003 The method was used to test inhibition of human and mouse CYP2A enzymes by three phenylethylamine derivatives 2-(p-tolyl)-ethylamine, amphetamine, 2-phenylethylamine and benzaldehyde, and two of its derivatives, 4-methylbenzaldehyde and 4-methoxybenzaldehyde. benzaldehyde 170-182 cytochrome P450, family 2, subfamily a Mus musculus 58-63 12746108-6 2003 The benzaldehyde derivatives were more potent inhibitors of CYP2A5 than the phenylethylamines. benzaldehyde 4-16 cytochrome P450, family 2, subfamily a, polypeptide 5 Mus musculus 60-66 12746108-9 2003 Amphetamine is a weak inhibitor of CYP2A6, whereas benzaldehyde is a suicide inhibitor with K(inact) = 0.16 min(-1) and K(I) = 18 micro M. The K(ic) values of 2-phenylethylamine, 2-(p-tolyl)-ethylamine, 4-methylbenzaldehyde and 4-methoxybenzaldehyde were 1.13, 0.23, 0.36 and 0.73 micro M for CYP2A6, respectively. benzaldehyde 51-63 cytochrome P450 family 2 subfamily A member 6 Homo sapiens 293-299 12590526-2 2003 For instance, the reaction of trimethylsilyl nitronate 2 (R(1) = Me) with benzaldehyde (R(2) = Ph) in THF in the presence of (S,S)-1 (2 mol %) proceeded smoothly at -78 degrees C, giving the corresponding nitroaldol adduct 3 (R(1) = Me, R(2) = Ph) in 92% isolated yield (anti/syn = 92:8) with 95% ee (anti isomer). benzaldehyde 74-86 synemin Homo sapiens 276-279 12105956-6 2002 Using this technique benzaldehyde and vanillin were observed to bind with bovine serum albumin, whereas 2-phenylethanol was identified as a nonbinding or weakly binding ligand with BSA. benzaldehyde 21-33 albumin Homo sapiens 81-94 12196396-7 2002 Behavioral assays show that a threefold decrease in DSC1 mRNA is accompanied by a threefold shift in the dose response for avoidance of the repellent odorant, benzaldehyde, toward higher odorant concentrations. benzaldehyde 159-171 Na channel protein 60E Drosophila melanogaster 52-56 11855704-4 2002 The immobilized TADDOLs were titanated to give (iPrO)2Ti-, Cl2Ti-, or (TosO)2Ti-TADDOLates which were used for catalyzing the additions of Et2Zn or Bu2Zn to PhCHO and of diphenyl nitrone to 3-crotonoyl-oxazolidinone. benzaldehyde 157-162 Fc mu receptor Homo sapiens 71-75 12047152-2 2002 Treatment of these substrates with TpRu(PPh3)(CH3CN)2PF6 (8.0 mol %) catalyst in 1,2-dichloroethane (80 degrees C, 12 h) afforded functionalized 1,3-dienes and benzyl aldehyde in good yields. benzaldehyde 160-175 caveolin 1 Homo sapiens 40-44 12036350-7 2002 We describe herein the rational design and synthesis of a class of imine conjugates produced by coupling amino acids to a range of benzaldehyde derivatives that inhibit MIF tautomerase and biological activities. benzaldehyde 131-143 macrophage migration inhibitory factor Homo sapiens 169-172 12036350-14 2002 The inhibitory activity of amino acid-benzaldehyde Schiff base-type MIF antagonists is the first step toward a meaningful structure/function analysis of inhibitors of MIF cellular bioactivities. benzaldehyde 38-50 macrophage migration inhibitory factor Homo sapiens 68-71 12036350-14 2002 The inhibitory activity of amino acid-benzaldehyde Schiff base-type MIF antagonists is the first step toward a meaningful structure/function analysis of inhibitors of MIF cellular bioactivities. benzaldehyde 38-50 macrophage migration inhibitory factor Homo sapiens 167-170 11487650-7 2001 Of a sample of eight glomeruli measured, dorsal medial (DM) 2 and ventral (V) were affected by benzaldehyde exposure, whereas DM6 was affected by isoamyl acetate. benzaldehyde 95-107 tarsal-less 2A Drosophila melanogaster 41-61 11569919-4 2001 Cytosolic AO was characterised using both the metabolism of N-[(2-dimethylamino)ethyl] acridine-4-carboxamide (DACA) and benzaldehyde to form DACA-9(10H)-acridone (quantified by HPLC with fluorescence detection) and benzoic acid (quantified spectrophotometrically). benzaldehyde 121-133 aldehyde oxidase 1 Homo sapiens 10-12 11481495-5 2001 Electroantennogram recordings from transformed and wild-type flies were used to identify cyclohexanol, cyclohexanone, benzaldehyde, and benzyl alcohol as ligands for the Or43a. benzaldehyde 118-130 Odorant receptor 43a Drosophila melanogaster 170-175 11425590-0 2001 Hydroxy- or methoxy-substituted benzaldoximes and benzaldehyde-O-alkyloximes as tyrosinase inhibitors. benzaldehyde 50-62 tyrosinase Homo sapiens 80-90 11456132-2 2001 Monkey liver cytosol exhibited significant reductase activities toward zonisamide, sulindac and imipramine N-oxide in the presence of 2-hydroxypyrimidine or benzaldehyde, an electron donor to aldehyde oxidase. benzaldehyde 157-169 aldehyde oxidase 1 Homo sapiens 192-208 11073254-2 2000 Since the addition of the photoexcited benzaldehyde at the unsaturated heterocycle proceeds in a syn fashion, the benzyl group at C-2 and the hydroxy group at C-3 of the product are cis oriented. benzaldehyde 39-51 complement C2 Homo sapiens 130-133 11306050-12 2001 Paradoxically, cells expressing ALDH3A1 were 1.5-fold more sensitive to benzaldehyde toxicity than control V79 cells. benzaldehyde 72-84 aldehyde dehydrogenase, dimeric NADP-preferring Cricetulus griseus 32-39 11306037-3 2001 Chloramphenicol which also elutes the enzyme from the affinity column, shows a discriminatory effect by inhibiting the ALDH1 oxidation of benzaldehyde and activating that of propionaldehyde while showing no effect when assayed with hexanal or cyclohexane-carboxaldehyde. benzaldehyde 138-150 aldehyde dehydrogenase 1 family member A1 Homo sapiens 119-124 11306044-4 2001 Finally, our quantum mechanical model of benzaldehyde in the active site of ALDH demonstrates that the enzyme requires only minor conformational changes to be poised for nucleophilic attack on the substrate. benzaldehyde 41-53 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 76-80 11306045-8 2001 Four hours after treatment with 25 microM ATEM, ALDH activity using benzaldehyde or propionaldehyde in hepatoma cells was decreased by 40% and cell number by 15% compared with controls. benzaldehyde 68-80 aldehyde dehydrogenase 2 family member Rattus norvegicus 48-52 11073254-2 2000 Since the addition of the photoexcited benzaldehyde at the unsaturated heterocycle proceeds in a syn fashion, the benzyl group at C-2 and the hydroxy group at C-3 of the product are cis oriented. benzaldehyde 39-51 complement C3 Homo sapiens 159-162 10956534-0 2000 Kinetic investigations of product inhibition in the amino alcohol-catalyzed asymmetric alkylation of benzaldehyde with diethylzinc In situ reaction rate measurements help to define the role of product inhibition in the asymmetric alkylation of benzaldehyde with diethylzinc using (-)-MIB as a chiral reagent. benzaldehyde 101-113 MIB E3 ubiquitin protein ligase 1 Homo sapiens 284-287 11009367-0 2000 Stereocontrol in rare earth metal triflate-catalyzed 1,3-dipolar cycloaddition reaction of 2-benzopyrylium-4-olate with aldehydes Exo-cycloadduct was obtained with high stereoselectivity by the addition of ytterbium triflate (Yb(OTf)(3)) (10 mol %) in the rhodium(II) acetate (Rh(2)(OAc)(4))-catalyzed decomposition of o-(methoxycarbonyl)-alpha-diazoacetophenone in the presence of benzaldehyde. benzaldehyde 382-394 POU class 5 homeobox 1 Homo sapiens 226-235 10998257-8 2000 ALDH1 was more efficient at oxidizing acetaldehyde, propionaldehyde, and benzaldehyde and was more sensitive to disulfiram inhibition. benzaldehyde 73-85 aldehyde dehydrogenase 1 family, member A1 Rattus norvegicus 0-5 10893244-7 2000 Furthermore, the AOH1 protein has benzaldehyde oxidizing activity with electrophoretic characteristics identical to those of a previously identified aldehyde oxidase isoenzyme (Holmes, R. S. (1979) Biochem. benzaldehyde 34-46 aldehyde oxidase 3 Mus musculus 17-21 10956534-0 2000 Kinetic investigations of product inhibition in the amino alcohol-catalyzed asymmetric alkylation of benzaldehyde with diethylzinc In situ reaction rate measurements help to define the role of product inhibition in the asymmetric alkylation of benzaldehyde with diethylzinc using (-)-MIB as a chiral reagent. benzaldehyde 244-256 MIB E3 ubiquitin protein ligase 1 Homo sapiens 284-287 10856427-7 2000 The two polymorphic forms of hALDH3 had identical kinetics with either benzaldehyde or aldophosphamide as substrate. benzaldehyde 71-83 aldehyde dehydrogenase 3 family member A1 Homo sapiens 29-35 9514081-6 1998 Each inhibited NAD-linked benzaldehyde oxidation catalyzed by ALDH-3s purified from human breast adenocarcinoma MCF-7/0/CAT cells (IC50 values were 16 and 0.75 microM, respectively) and human normal stomach mucosa (IC50 values were 202 and 5 microM, respectively). benzaldehyde 26-38 aldehyde dehydrogenase 3 family member A1 Homo sapiens 62-68 11674100-5 1999 gamma-Alkoxyallylindium reagents were prepared by treating the corresponding gamma-alkoxyallyllithium with indium trichloride and reacted with benzaldehyde to give vic-diol mono ethers in high yields with good syn selectivity. benzaldehyde 143-155 synemin Homo sapiens 210-213 9852085-5 1998 Purified aryl-aldehyde oxidoreductase was incubated in NMR tubes together with either carboxy-13C-benzoyl-AMP or carboxy-13C-benzoic acid to demonstrate that benzoyl-AMP is an active intermediate during the enzymatic reduction of benzoic acid to benzaldehyde. benzaldehyde 246-258 hydroxysteroid 17-beta dehydrogenase 6 Homo sapiens 23-37 11672264-4 1998 Polymer-supported amino alcohols 5a-c have been evaluated as catalytic ligands in the enantioselective addition of diethylzinc to benzaldehyde, best results being obtained with the cis-2,6-dimethylpiperidine containing ligand 5c. benzaldehyde 130-142 suppressor of cytokine signaling 2 Homo sapiens 181-186 10744688-7 2000 In comparison to E. coli expressing only xylMA, the presence of xylB lowered product formation rates and resulted in back formation of benzyl alcohol from benzaldehyde. benzaldehyde 155-167 xylulokinase Pseudomonas putida 64-68 10744688-9 2000 In the case of high fluxes through the degradation pathways and low aldehyde concentrations, XylB may contribute to benzaldehyde formation via the energetically favorable dehydrogenation of benzyl alcohols. benzaldehyde 116-128 xylulokinase Pseudomonas putida 93-97 10683765-3 1999 The variations were correlated to the concentrations of aldehyde oxidase activity in human subjects assayed with benzaldehyde as a substrate. benzaldehyde 113-125 aldehyde oxidase 1 Homo sapiens 56-72 9726784-10 1998 For CYP2B1 and CYP1A1, the order of inhibitory potency was toluene > benzaldehyde > benzyl alcohol and suggests that both the parent molecule and its metabolites may act in concert to inhibit catalytic activity of these cytochromes. benzaldehyde 72-84 cytochrome P450, family 2, subfamily b, polypeptide 1 Rattus norvegicus 4-10 9726784-10 1998 For CYP2B1 and CYP1A1, the order of inhibitory potency was toluene > benzaldehyde > benzyl alcohol and suggests that both the parent molecule and its metabolites may act in concert to inhibit catalytic activity of these cytochromes. benzaldehyde 72-84 cytochrome P450, family 1, subfamily a, polypeptide 1 Rattus norvegicus 15-21 9161710-4 1997 Similarly, variations in aldehyde oxidase activity were found in the monkey liver preparations when assayed with benzaldehyde or N1-methylnicotinamide. benzaldehyde 113-125 aldehyde oxidase 1 Homo sapiens 25-41 9292276-7 1997 Particularly, BA was highly toxic to the HTC cells, which possessed the highest ALDH levels. benzaldehyde 14-16 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 80-84 9292276-8 1997 Moreover, the treatment with (diethylamino)benzaldehyde, an ALDH inhibitor, completely abolished the toxicity of BA. benzaldehyde 113-115 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 60-64 11667478-4 1996 Among numerous solid supports of the aluminosilicate type, the K10 montmorillonite clay was found to be best at achieving quantitative formation of benzaldehyde, without any overoxidation to benzoic acid. benzaldehyde 148-160 keratin 10 Homo sapiens 63-66 8975763-4 1996 We have found that benzaldehyde effectively inactivates the antioxidant enzyme glutathione peroxidase (Ki approximately 15 microM), but has no effect on the other antioxidant enzymes tested: catalase, superoxide dismutase, and glutathione reductase. benzaldehyde 19-31 catalase Rattus norvegicus 191-199 8975763-4 1996 We have found that benzaldehyde effectively inactivates the antioxidant enzyme glutathione peroxidase (Ki approximately 15 microM), but has no effect on the other antioxidant enzymes tested: catalase, superoxide dismutase, and glutathione reductase. benzaldehyde 19-31 glutathione-disulfide reductase Rattus norvegicus 227-248 8663198-9 1996 RalDH(II) does not recognize citral, benzaldehyde, acetaldehyde, and propanal efficiently as substrates, but does metabolize octanal and decanal efficiently. benzaldehyde 37-49 aldehyde dehydrogenase 1 family, member A2 Rattus norvegicus 0-9 8937651-4 1996 The present investigation revealed that small amounts of this enzyme are also present in human salivary glands; mean values for ALDH-3 activities (NADP-dependent enzyme-catalysed oxidation of benzaldehyde) in cytosolic fractions prepared from submandibular and parotid glands were 52 (range: 29-92) and 44 (range: 13-73) mIU/g tissue, respectively. benzaldehyde 192-204 aldehyde dehydrogenase 3 family member A1 Homo sapiens 128-134 7944384-2 1994 The protein radical is unstable and decays within 5 min, but the ferryl species is stable for more than 1 h. Previous studies have shown that styrene is oxidized to styrene oxide and benzaldehyde by ferric Mb and H2O2. benzaldehyde 183-195 myoglobin Equus caballus 206-208 8662659-10 1996 Clones expressing elevated human (386-5938 milliunits/mg) or rat (4-597 milliunits/mg, benzaldehyde/NADP+ substrate) ALDH-3 activity were 1.3- to 12-fold resistant to mafosfamide relative to control cells (<1 milliunit/mg). benzaldehyde 87-99 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 117-123 8654195-4 1995 ALDH-3 activities (NADP-dependent catalysis of benzaldehyde oxidation) were 1.7, 212, and 183 mlU/10(7) cells in sham-electroporated MCF-7/0 cells, and MCF-7/0 cells electroporated with stomach mucosa ALDH-3 and catechol-induced MCF-7/0 ALDH-3, respectively. benzaldehyde 47-59 aldehyde dehydrogenase 3 family member A1 Homo sapiens 0-6 8431420-6 1993 Further, the enzyme purified to homogeneity by following activity with 17-hydroxyprogesterone as a substrate was shown to reduce glucose, glyceraldehyde, and benzaldehyde (all classic aldose reductase substrates). benzaldehyde 158-170 aldose reductase Bos taurus 184-200 8083225-5 1994 Pretreatment of the highest activity cell line (3A1-31A) with 75 microM diethylaminobenzaldehyde, an ALDH substrate and inhibitor of benzaldehyde oxidation, effectively reversed the 3.8-fold resistance in this line; drug sensitivity was unaffected by diethylaminobenzaldehyde in the control transfected cell line. benzaldehyde 84-96 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 101-105 8068047-4 1994 when the ability to catalyse the oxidation of aldophosphamide is normalized by the ability to catalyse the oxidation of benzaldehyde, each of these enzymes, as well as the type-2 ALDH-3 found in MCF-7/OAP cells, exhibits greater ability to catalyse the oxidation of aldophosphamide than does stomach mucosa type-1 ALDH-3; hence, although not type-2 ALDH-3s, they may be slight variants of the prototypical type-1 ALDH-3. benzaldehyde 120-132 aldehyde dehydrogenase 3 family member A1 Homo sapiens 314-320 8068047-4 1994 when the ability to catalyse the oxidation of aldophosphamide is normalized by the ability to catalyse the oxidation of benzaldehyde, each of these enzymes, as well as the type-2 ALDH-3 found in MCF-7/OAP cells, exhibits greater ability to catalyse the oxidation of aldophosphamide than does stomach mucosa type-1 ALDH-3; hence, although not type-2 ALDH-3s, they may be slight variants of the prototypical type-1 ALDH-3. benzaldehyde 120-132 aldehyde dehydrogenase 3 family member A1 Homo sapiens 314-320 1505055-2 1992 The induced activity could be detected with benzaldehyde as substrate and NADP as cofactor (B/NADP ALDH). benzaldehyde 44-56 aldehyde dehydrogenase family 3, subfamily A1 Mus musculus 99-103 1483503-7 1992 BCP 54 preferentially oxidizes aromatic aldehyde such as benzaldehyde with NAD as coenzyme, but cannot oxidize phenylacetaldehyde. benzaldehyde 31-48 aldehyde dehydrogenase 3 family member A1 Bos taurus 0-6 1483503-7 1992 BCP 54 preferentially oxidizes aromatic aldehyde such as benzaldehyde with NAD as coenzyme, but cannot oxidize phenylacetaldehyde. benzaldehyde 57-69 aldehyde dehydrogenase 3 family member A1 Bos taurus 0-6 8168375-2 1993 (1) A genetic screen has yielded olfactory mutants, of which one, acj6, shows greatly reduced electrical responses of its olfactory organs to all odorants tested except benzaldehyde (odour of almond). benzaldehyde 169-181 abnormal chemosensory jump 6 Drosophila melanogaster 66-70 1281448-4 1992 Measurement of the non-P450-mediated activities epoxide hydrolase, DT-diaphorase, and aldehyde dehydrogenase (NADP+, benzaldehyde) revealed < 4-fold inductions following feeding of 33 ppm Aroclor. benzaldehyde 117-129 NAD(P)H quinone dehydrogenase 1 Rattus norvegicus 67-108 1460467-3 1992 Interestingly, abnormal chemosensory jump 6 (acj6) reduces response in the maxillary palp to all odorants tested except benzaldehyde (odor of almond), as if response to benzaldehyde is mediated through a different type of odorant pathway from the other odorants. benzaldehyde 120-132 abnormal chemosensory jump 6 Drosophila melanogaster 45-49 1460467-3 1992 Interestingly, abnormal chemosensory jump 6 (acj6) reduces response in the maxillary palp to all odorants tested except benzaldehyde (odor of almond), as if response to benzaldehyde is mediated through a different type of odorant pathway from the other odorants. benzaldehyde 169-181 abnormal chemosensory jump 6 Drosophila melanogaster 45-49 2060039-3 1991 The cytosolic ALDH activity of the liver was determined either with propionaldehyde and NAD (P/NAD), or with benzaldehyde and NADP (B/NADP). benzaldehyde 109-121 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 14-18 2029738-14 1991 The inducibility of benzaldehyde:NADP aldehyde dehydrogenase in rat liver exceeds by orders of magnitude the ability of the same inducers to increase the amount of the activity of other drug metabolizing enzymes such as glutathione S-transferase, cytochrome P450 and cytochrome b5. benzaldehyde 20-32 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 247-280 16348226-9 1990 GS-15 oxidized potential aromatic intermediates in the oxidation of toluene (benzylalcohol and benzaldehyde) and p-cresol (p-hydroxybenzylalcohol and p-hydroxybenzaldehyde). benzaldehyde 95-107 Bet1 golgi vesicular membrane trafficking protein like Homo sapiens 0-5 2400809-6 1990 Levels of aldehyde dehydrogenase (ALDH), which inactivates CY by prevention of formation of PhM, were significantly elevated in these CY-resistant AML cells: cytosolic and particulate ALDH fractions from these cells were 11 to 13 times control with NAD cofactor and propanal substrate and three to four times control with NADP cofactor and benzaldehyde substrate. benzaldehyde 340-352 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 10-32 2400809-6 1990 Levels of aldehyde dehydrogenase (ALDH), which inactivates CY by prevention of formation of PhM, were significantly elevated in these CY-resistant AML cells: cytosolic and particulate ALDH fractions from these cells were 11 to 13 times control with NAD cofactor and propanal substrate and three to four times control with NADP cofactor and benzaldehyde substrate. benzaldehyde 340-352 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 34-38 2202600-2 1990 Benzyl alcohol dehydrogenase catalyses the oxidation of benzyl alcohol to benzaldehyde with the concomitant reduction of NAD+; the reaction is reversible. benzaldehyde 74-86 benzyl alcohol dehydrogenase Pseudomonas putida 0-28 2202600-5 1990 The apparent Km value of benzyl alcohol dehydrogenase for benzyl alcohol was 220 microM, while that of benzaldehyde dehydrogenase for benzaldehyde was 460 microM. benzaldehyde 103-115 benzyl alcohol dehydrogenase Pseudomonas putida 25-53 1981531-7 1990 On the other hand, coinfusion of an electron donor for aldehyde oxidase such as 2-hydroxypyrimidine and benzaldehyde, but not xanthine, markedly stimulated the formation of DPS during hypoxia. benzaldehyde 104-116 aldehyde oxidase 1 Homo sapiens 55-71 1981539-8 1990 These results suggest that cytochrome P-450, rather than alcohol dehydrogenase, was responsible for the metabolism of benzyl alcohol to benzaldehyde. benzaldehyde 136-148 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 27-78 2123349-1 1990 An olfactory gene olfE, which affects response to benzaldehyde in larvae and adults of Drosophila melanogaster, has been mapped between two breakpoints on the X chromosome. benzaldehyde 50-62 swiss cheese Drosophila melanogaster 18-22 12692643-0 1990 NTP Toxicology and Carcinogenesis Studies of Benzaldehyde (CAS No. benzaldehyde 45-57 BCAR1 scaffold protein, Cas family member Rattus norvegicus 59-62 33587902-2 2021 The results show the reaction starts with the nucleophilic attack of the C2alpha atom of the HEThDP intermediate on the Cbeta atom of the carbonyl group of benzaldehyde substrate via the formation of a transition state (TS1) with the HEThDP intermediate under 4"-aminopyrimidium (APH+) form. benzaldehyde 156-168 acylaminoacyl-peptide hydrolase Homo sapiens 280-283 33821889-7 2021 We observed that in the presence of 5 mM H2O2, H64DOPA Mb oxidizes thioanisole and benzaldehyde with a 10 and 54 folds higher rate, respectively, as opposed to WT Mb. benzaldehyde 83-95 myoglobin Homo sapiens 55-57 2302256-3 1990 The fraction of cells surviving a 2 hr treatment with 10 microM cis-DDP increased from 0.012 +/- 0.004 to 0.10 +/- 0.03 when treatment was combined with at least 1 mM benzaldehyde or at least 0.2 mM salicylaldehyde. benzaldehyde 167-179 translocase of inner mitochondrial membrane 8A Homo sapiens 68-71 34500150-4 2022 The catalytic performance of Pd@CTF-1 was demonstrated by the one-pot N-alkylation of benzaldehyde with aniline (or nitrobenzene) under mild reaction conditions, and Pd@CTF-1 exhibited a wide range of general applicability for N-alkylation reactions. benzaldehyde 86-98 cardiotrophin 1 Homo sapiens 32-37 34856193-3 2022 Some of these AOX substrates are odorants, such as benzaldehyde and n-octanal. benzaldehyde 51-63 acyl-Coenzyme A oxidase 1, palmitoyl Mus musculus 14-17 34500150-4 2022 The catalytic performance of Pd@CTF-1 was demonstrated by the one-pot N-alkylation of benzaldehyde with aniline (or nitrobenzene) under mild reaction conditions, and Pd@CTF-1 exhibited a wide range of general applicability for N-alkylation reactions. benzaldehyde 86-98 cardiotrophin 1 Homo sapiens 169-174 34587326-5 2021 Similarly, higher levels of acrolein, benzaldehyde, crotonaldehyde, propionaldehyde, trans-2-hexenal and acetaldehyde were accumulated in aao3 mutants upon UV-C irradiation. benzaldehyde 38-50 abscisic aldehyde oxidase 3 Arabidopsis thaliana 138-142 34302583-9 2022 PFN-1/Benzaldehyde complexes identified 20 accessible amino acids to HDX that participate in the docking simulation in the surface of WT and mutant PFN-1. benzaldehyde 6-18 profilin 1 Homo sapiens 0-5 34302583-9 2022 PFN-1/Benzaldehyde complexes identified 20 accessible amino acids to HDX that participate in the docking simulation in the surface of WT and mutant PFN-1. benzaldehyde 6-18 profilin 1 Homo sapiens 148-153 34893654-8 2021 Ni-Pth selectively yielded benzaldehyde. benzaldehyde 27-39 parathyroid hormone Homo sapiens 3-6 34587326-6 2021 Aldehydes application to plants hastened profuse senescence symptoms and higher accumulation of aldehydes, such as acrolein, benzaldehyde and 4-hydroxy-2-nonenal, in aao3 mutant leaves as compared to WT. benzaldehyde 125-137 abscisic aldehyde oxidase 3 Arabidopsis thaliana 166-170 34689562-5 2021 When applying benzyl alcohol to consume photogenerated holes, CN/BP@Ni enables the selective production of benzaldehyde; therefore, two value-added products are obtained in a single closed redox cycle. benzaldehyde 107-119 CCHC-type zinc finger nucleic acid binding protein Homo sapiens 62-67 34726214-1 2021 Thiol-functionalized UiO-66-anchored atomically dispersed metal ions, denoted as UiO-66(SM)2 (M = Pd, Pt, or Au), were prepared as photocatalysts for the selective oxidation of benzyl alcohol (BA) to benzaldehyde (BAD) under visible light irradiation. benzaldehyde 200-212 SM2 Homo sapiens 81-92 34598435-2 2021 The ligand-enabled regiocontrol, such as in the borylation of benzaldehyde, the selectivity could be switched from the ortho to meta position, under identical conditions, by just changing the external ligand (L) from 8-aminoquinoline (8-AQ) to tetramethylphenanthroline (TMP). benzaldehyde 62-74 epithelial membrane protein 1 Homo sapiens 271-274 34138542-5 2021 Pt1/N-CNTs exhibits 99% substrate conversion with 81% yield of benzaldehyde, which is exceptional and unprecedented compared with previously reported electrocatalysts. benzaldehyde 63-75 zinc finger protein 77 Homo sapiens 0-3 34378958-9 2021 Ald has a broad range of substrates, including benzaldehyde, furfural, and acetaldehyde. benzaldehyde 47-59 AWN88_RS16050 Agrobacterium tumefaciens 0-3 34368547-7 2021 A maximum of 78% benzaldehyde selectivity was obtained with 0.06 g of catalyst CH1 after 18 h of toluene oxidation activity. benzaldehyde 17-29 SUN domain containing ossification factor Homo sapiens 79-82 34138542-6 2021 Moreover, Pt1/N-CNTs using only 0.41 wt % Pt achieved a much higher benzaldehyde yield than those of the state-of-the-art bulk Pt electrode (100 wt % Pt) and commercial Pt/C catalyst (20 wt % Pt). benzaldehyde 68-80 zinc finger protein 77 Homo sapiens 10-13 35306285-9 2022 The developed B-mBP-ZnO catalyst exhibited superior performances in photo-oxidation of CEES to chloroethyl ethyl sulfoxide and benzyl alcohol to benzaldehyde. benzaldehyde 145-157 growth differentiation factor 5 Mus musculus 16-19 35424977-3 2022 Moreover, the complexation behaviors of HP-beta-CD with benzaldehyde and intermediates were studied by UV-vis and 2D-ROESY NMR spectroscopies to reveal the plausible mechanisms of the reactions, and HP-beta-CD did not act as a simple phase transfer agent. benzaldehyde 56-68 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 43-50 35605284-4 2022 A high H2 production rate of 8.9 mmol h-1 g-1 is delivered over the optimal ZnIn2S4/Nix-B with a stoichiometric production of benzaldehyde, which is about 22 times higher than ZnIn2S4. benzaldehyde 126-138 BCL2 interacting protein 3 like Homo sapiens 84-87 35452068-10 2022 Furthermore, the catalytic activity of DUT-52-(NH2)2-1" was tested in the Knoevenagel condensation between benzaldehyde and cyanoacetamide. benzaldehyde 107-119 deoxyuridine triphosphatase Homo sapiens 39-42 2805229-3 1989 The ALDH phenotype was determined at intervals over 42 weeks by histochemical analysis, total ALDH activity assays and gel electrophoresis using propionaldehyde and NAD (P-NAD) which characterizes class 1 and 2 ALDH, or benzaldehyde and NADP (B-NADP) to determine class 3 ALDH. benzaldehyde 220-232 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 4-8 2755909-8 1989 An increase of the activity was also noticed when ALDH was measured with NADP and benzaldehyde (B/NADP). benzaldehyde 82-94 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 50-54 2765201-5 1989 Alcohol-resistant AT rats had higher ALDH activity, with benzaldehyde, in most CNS structures than did the alcohol-sensitive ANT"s, significantly so in the lamina II of the somatosensory cortex and the neurons of the lateral hypothalamic area. benzaldehyde 57-69 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 37-41 3811968-4 1986 The activity of ALDH is not only preserved, but also significantly enhanced, when propionaldehyde, phenylacetaldehyde, benzaldehyde and D-glucuronolactone are used as substrates and NAD as the coenzyme. benzaldehyde 119-131 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 16-20 2827759-5 1987 These probes, as well as a benzaldehyde analogue of phosphatidic acid, and a water-soluble benzaldehyde reagent were covalently attached to bovine heart cytochrome c oxidase. benzaldehyde 27-39 cytochrome c oxidase subunit 6A1, mitochondrial Bos taurus 153-173 2827759-5 1987 These probes, as well as a benzaldehyde analogue of phosphatidic acid, and a water-soluble benzaldehyde reagent were covalently attached to bovine heart cytochrome c oxidase. benzaldehyde 91-103 cytochrome c oxidase subunit 6A1, mitochondrial Bos taurus 153-173 3466164-4 1986 The kcat/Km values for the reduction of benzaldehyde, 3,4-dihydroxybenzaldehyde and 4-hydroxy-3-methoxybenzaldehyde by pi ADH are from 9- to 29-fold higher than those for a class I isozyme, beta 1 gamma 2 ADH. benzaldehyde 40-52 aldo-keto reductase family 1 member A1 Homo sapiens 122-125 3466164-4 1986 The kcat/Km values for the reduction of benzaldehyde, 3,4-dihydroxybenzaldehyde and 4-hydroxy-3-methoxybenzaldehyde by pi ADH are from 9- to 29-fold higher than those for a class I isozyme, beta 1 gamma 2 ADH. benzaldehyde 40-52 aldo-keto reductase family 1 member A1 Homo sapiens 205-208 3343508-9 1988 AlDH in upper GI tissues and in liver nodules shared three characteristics: a sharp localization; a preference for Bz and NADP compared to the aliphatic substrate acetaldehyde and NAD; and a high co-enzyme-independent activity in the presence of Bz. benzaldehyde 115-117 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 0-4 3343508-9 1988 AlDH in upper GI tissues and in liver nodules shared three characteristics: a sharp localization; a preference for Bz and NADP compared to the aliphatic substrate acetaldehyde and NAD; and a high co-enzyme-independent activity in the presence of Bz. benzaldehyde 246-248 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 0-4 3811968-5 1986 A relative increase of activity is also noted when ALDH is measured with benzaldehyde and NADP. benzaldehyde 73-85 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 51-55 3003181-1 1986 Hepatocarcinogenesis in rats treated with several chemicals is associated with changes in aldehyde dehydrogenase (AlDH) activity, particularly heterogeneous expression of a "tumor specific" phenotype that is very active with aromatic aldehydes, e.g., benzaldehyde (Bz). benzaldehyde 251-263 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 90-112 3008991-2 1986 Like the tumor-associated aldehyde dehydrogenase, bladder NADP+-ALDH is cytosolic and preferentially oxidizes benzaldehyde-like aromatic aldehydes. benzaldehyde 110-122 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 26-48 3008991-2 1986 Like the tumor-associated aldehyde dehydrogenase, bladder NADP+-ALDH is cytosolic and preferentially oxidizes benzaldehyde-like aromatic aldehydes. benzaldehyde 110-122 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 64-68 3083781-3 1986 In an NADPH-supported reduction reaction, aldose reductase exhibited similar activity toward benzaldehyde and glyceraldehyde, but benzyl alcohol was a much better substrate than physiological polyols in the analog-dependent oxidation reaction: relative kcat/Km ratios were 740 for benzyl alcohol, 2.2 for xylitol, and 1.0 for glycerol. benzaldehyde 93-105 aldo-keto reductase family 1 member B1 Rattus norvegicus 42-58 3003181-2 1986 Objectives of this study were first, to determine if liver cancers in vinyl chloride-treated rats also expressed this AlDH phenotype, and second, to quantitate the NAD- and NADP-dependent AlDH activity for the substrates Bz and acetaldehyde (Ac) in the cancers and surrounding tissue. benzaldehyde 221-223 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 118-122 3003181-2 1986 Objectives of this study were first, to determine if liver cancers in vinyl chloride-treated rats also expressed this AlDH phenotype, and second, to quantitate the NAD- and NADP-dependent AlDH activity for the substrates Bz and acetaldehyde (Ac) in the cancers and surrounding tissue. benzaldehyde 221-223 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 188-192 3003181-1 1986 Hepatocarcinogenesis in rats treated with several chemicals is associated with changes in aldehyde dehydrogenase (AlDH) activity, particularly heterogeneous expression of a "tumor specific" phenotype that is very active with aromatic aldehydes, e.g., benzaldehyde (Bz). benzaldehyde 251-263 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 114-118 3003181-1 1986 Hepatocarcinogenesis in rats treated with several chemicals is associated with changes in aldehyde dehydrogenase (AlDH) activity, particularly heterogeneous expression of a "tumor specific" phenotype that is very active with aromatic aldehydes, e.g., benzaldehyde (Bz). benzaldehyde 265-267 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 90-112 3003181-1 1986 Hepatocarcinogenesis in rats treated with several chemicals is associated with changes in aldehyde dehydrogenase (AlDH) activity, particularly heterogeneous expression of a "tumor specific" phenotype that is very active with aromatic aldehydes, e.g., benzaldehyde (Bz). benzaldehyde 265-267 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 114-118 3994763-4 1985 When the Km values for benzaldehyde with aldehyde dehydrogenase (ALDH) were determined, two Km values (3 and 120 microM) were obtained with mitochondria, but only a single Km value (25 microM) was obtained with the cytosolic fraction. benzaldehyde 23-35 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 41-63 4073832-3 1985 The ALDH3 isozymes show optimal activity with benzaldehyde and can use either NAD or NADP as cofactor. benzaldehyde 46-58 aldehyde dehydrogenase 3 family member A1 Homo sapiens 4-9 3994763-4 1985 When the Km values for benzaldehyde with aldehyde dehydrogenase (ALDH) were determined, two Km values (3 and 120 microM) were obtained with mitochondria, but only a single Km value (25 microM) was obtained with the cytosolic fraction. benzaldehyde 23-35 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 65-69 3994763-6 1985 In intact mitochondria, with 200 microM acetaldehyde or benzaldehyde the matrix space enzyme accounted for 77 and 62%, respectively, of the total ALDH activity. benzaldehyde 56-68 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 146-150 3994763-13 1985 It can be concluded that, in rat, disulfiram inhibiting liver ALDH not only affects oxidation of acetaldehyde, but also that of benzaldehyde. benzaldehyde 128-140 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 62-66 4015840-3 1985 One isozyme, designated ALDH3, which is very active against benzaldehyde, was found to show variable expression in hybrids made between rat hepatoma cells and human fibroblasts or fetal liver. benzaldehyde 60-72 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 24-29 6149820-2 1984 The hepatic ALDH phenotype was determined at intervals over 280 days by histochemical analysis, total ALDH activity assays and gel electrophoresis, using propionaldehyde and NAD (P/NAD) to characterize normal liver ALDH activity or benzaldehyde and NADP (B/NADP) to determine tumor-associated ALDH activity. benzaldehyde 232-244 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 12-16 4226961-3 1967 When the aromatic aldehyde benzaldehyde is used as substrate, human liver aldehyde oxidase, like the rabbit enzyme, is strongly inhibited by menadione, estradiol-17beta, antimycin A, Triton X-100, and N-alkylphenothiazines; the human enzyme differs from the rabbit enzyme, however, in being relatively insensitive to oligomycin and Amytal. benzaldehyde 27-39 aldehyde oxidase 1 Homo sapiens 74-90 6662893-3 1983 p-Sulfamoylbenzaldehyde and benzaldehyde formed enzymatically from p-sulfamoylbenzylamine (the substrate of monoamine oxidase A) and benzylamine (the substrate of monoamine oxidase B), respectively, are converted simultaneously into fluorescent compounds with 2,2"-dithiobis(1-aminonaphthalene). benzaldehyde 11-23 monoamine oxidase A Rattus norvegicus 108-127 6662893-3 1983 p-Sulfamoylbenzaldehyde and benzaldehyde formed enzymatically from p-sulfamoylbenzylamine (the substrate of monoamine oxidase A) and benzylamine (the substrate of monoamine oxidase B), respectively, are converted simultaneously into fluorescent compounds with 2,2"-dithiobis(1-aminonaphthalene). benzaldehyde 11-23 monoamine oxidase B Rattus norvegicus 163-182 6196110-5 1983 During hepatocarcinogenesis, ALDH staining patterns in grossly normal liver range from normal-appearing to patterns of distinct, intense focal hepatocyte staining with propionaldehyde-NAD and/or benzaldehyde-NADP. benzaldehyde 195-207 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 29-33 6196110-8 1983 Neoplasms with elevated ALDH activity with propionaldehyde-NAD and/or benzaldehyde-NADP, as well as with no detectable ALDH, have been observed. benzaldehyde 70-82 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 24-28 27359-9 1978 Transient-state rate parameters for benzyl alcohol/benzaldehyde catalysis by liver alcohol dehydrogenase have been determined at different pH. benzaldehyde 51-63 aldo-keto reductase family 1 member A1 Homo sapiens 83-104 235278-9 1975 The equilibrium constant for hydride transfer from benzaldehyde to benzyl alcohol at pH 8.75 is K-eq equals kappa-H/kappa-H equals 42; this constant has important consequences concerning subunit interactions during liver alcohol dehydrogenase catalysis. benzaldehyde 51-63 aldo-keto reductase family 1 member A1 Homo sapiens 221-242 6488182-4 1984 HTC, JM1, and JM2 express the tumor ALDH phenotype, as indicated by elevated NADP-dependent, benzaldehyde-oxidizing activity, the appearance of new isozymes by electrophoresis, and characteristic histochemical localization of ALDH activity in situ. benzaldehyde 93-105 aldehyde dehydrogenase 3 family, member A1 Rattus norvegicus 36-40 6388629-1 1984 The reduction of benzaldehyde and p-nitrobenzaldehyde by NADH, catalyzed by horse liver alcohol dehydrogenase (LADH), has been found to be faster when NADH is bound to glyceraldehyde-3-phosphate dehydrogenase (GPDH) than with free NADH. benzaldehyde 17-29 glyceraldehyde-3-phosphate dehydrogenase Equus caballus 168-208 6388629-1 1984 The reduction of benzaldehyde and p-nitrobenzaldehyde by NADH, catalyzed by horse liver alcohol dehydrogenase (LADH), has been found to be faster when NADH is bound to glyceraldehyde-3-phosphate dehydrogenase (GPDH) than with free NADH. benzaldehyde 17-29 glyceraldehyde-3-phosphate dehydrogenase Equus caballus 210-214 33141452-4 2021 In the presence of phenylcarbinol, ACN exhibited excellent pure water-splitting ability (95.3 mumol/h) and in the meanwhile phenylcarbinol was selectively oxidized to benzaldehyde (conversion of 90.9%, selectivity of 99.7%) under solar irradiation. benzaldehyde 167-179 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor Homo sapiens 35-38 34039986-6 2021 The produced Pt2/mpg-C3N4 samples are versatile and can be applied in catalyzing other important reactions, such as the selective hydrogenation of benzaldehyde and the epoxidation of styrene. benzaldehyde 147-159 N-methylpurine DNA glycosylase Homo sapiens 17-20 33617080-4 2021 Deprotonation of Si(C2F5)3H with sterically demanding phosphazene bases afforded thermally stable phosphazenium salts of the [Si(C2F5)3]- anion, which add to benzaldehyde, benzophenone, CS2 and CO2in various manners. benzaldehyde 158-170 chorionic somatomammotropin hormone 2 Homo sapiens 186-189 33885554-4 2021 The results of computations for several potential reaction pathways are juxtaposed with experiment-based calculations, which leads to stepwise mechanisms and energy profiles for the reactions of pinacolborane with benzaldehyde and acetophenone (in the presence of KF). benzaldehyde 214-226 arylformamidase Homo sapiens 264-266 33832752-2 2021 The results show the reaction starts with the nucleophilic attack of the C2alpha atom of the HEThDP intermediate on the Cbeta atom of the carbonyl group of benzaldehyde substrate via the formation of a transition state (TS1) with the HEThDP intermediate under 4"-aminopyrimidium (APH+) form. benzaldehyde 156-168 acylaminoacyl-peptide hydrolase Homo sapiens 280-283 33454360-3 2021 Data from read-across analog benzaldehyde (CAS # 100-52-7) show that p-tolualdehyde is not expected to be genotoxic. benzaldehyde 29-41 BCAR1 scaffold protein, Cas family member Homo sapiens 43-46 33563272-5 2021 Benzaldehyde preconditioning activates systemic cytoprotective stress responses involving DAF-16/FOXO, SKN-1/Nrf2, and Hsp90 in non-neuronal cells, which confer both physiological (increased survival) and behavioral tolerance (reduced food avoidance) to benzaldehyde exposure. benzaldehyde 0-12 NFE2 like bZIP transcription factor 2 Homo sapiens 109-113 33563272-5 2021 Benzaldehyde preconditioning activates systemic cytoprotective stress responses involving DAF-16/FOXO, SKN-1/Nrf2, and Hsp90 in non-neuronal cells, which confer both physiological (increased survival) and behavioral tolerance (reduced food avoidance) to benzaldehyde exposure. benzaldehyde 0-12 heat shock protein 90 alpha family class A member 1 Homo sapiens 119-124 33397797-0 2021 The G-protein coupled receptor SRX-97 is required for concentration dependent sensing of benzaldehyde in Caenorhabditis elegans. benzaldehyde 89-101 7TM_GPCR_Srx domain-containing protein Caenorhabditis elegans 31-37 33397797-7 2021 Analysis of CRISPR-based deletion mutants of the srx-97 locus suggests that this gene is involved in recognition of high concentrations of benzaldehyde. benzaldehyde 139-151 7TM_GPCR_Srx domain-containing protein Caenorhabditis elegans 49-55