PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 21572589-1 2011 A series of novel 3,5-diamino-1,2,4-triazole benzyl ureas was identified as having potent anaplastic lymphoma kinase (ALK) inhibition exemplified by 15a, 20a, and 23a, which exhibited antiproliferative IC(50) values of 70, 40, and 20 nM in Tel-ALK transformed Ba/F3 cells, respectively. 3,5-diamino-1,2,4-triazole benzyl ureas 18-57 anaplastic lymphoma kinase Mus musculus 90-116 21572589-1 2011 A series of novel 3,5-diamino-1,2,4-triazole benzyl ureas was identified as having potent anaplastic lymphoma kinase (ALK) inhibition exemplified by 15a, 20a, and 23a, which exhibited antiproliferative IC(50) values of 70, 40, and 20 nM in Tel-ALK transformed Ba/F3 cells, respectively. 3,5-diamino-1,2,4-triazole benzyl ureas 18-57 anaplastic lymphoma kinase Mus musculus 118-121 21572589-1 2011 A series of novel 3,5-diamino-1,2,4-triazole benzyl ureas was identified as having potent anaplastic lymphoma kinase (ALK) inhibition exemplified by 15a, 20a, and 23a, which exhibited antiproliferative IC(50) values of 70, 40, and 20 nM in Tel-ALK transformed Ba/F3 cells, respectively. 3,5-diamino-1,2,4-triazole benzyl ureas 18-57 ets variant 6 Mus musculus 240-243 21572589-1 2011 A series of novel 3,5-diamino-1,2,4-triazole benzyl ureas was identified as having potent anaplastic lymphoma kinase (ALK) inhibition exemplified by 15a, 20a, and 23a, which exhibited antiproliferative IC(50) values of 70, 40, and 20 nM in Tel-ALK transformed Ba/F3 cells, respectively. 3,5-diamino-1,2,4-triazole benzyl ureas 18-57 anaplastic lymphoma kinase Mus musculus 244-247