PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	latexin	Homo sapiens	112-115
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	mitogen-activated protein kinase 14	Homo sapiens	159-167
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	mitogen-activated protein kinase 11	Homo sapiens	169-176
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	mitogen-activated protein kinase 8	Homo sapiens	178-182
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	mitogen-activated protein kinase 9	Homo sapiens	184-188
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	mitogen-activated protein kinase 10	Homo sapiens	190-194
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	component of inhibitor of nuclear factor kappa B kinase complex	Homo sapiens	200-205
21489792-6	2011	In particular, compound 17 with the aromatic piperazinosulfonyl substituent showed the most potent (IC(50)=1.30 muM) and selective (over other kinases such as p38alpha, p38beta, JNK1, JNK2, JNK3, and IKK-1) inhibitory activity against IKK-2.	aromatic piperazinosulfonyl	36-63	inhibitor of nuclear factor kappa B kinase subunit beta	Homo sapiens	235-240