PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9890627-5	1999	The selective adenosine A2a-receptor antagonist aminophenol (ZM 241385) and the nonselective antagonist 8-phenyltheophylline (8-PT) inhibited these effects.	Aminophenols	48-59	adenosine A2a receptor	Rattus norvegicus	14-36
8017631-8	1994	The enzymatically generated product, aminophenol, is detected immediately by oxidation at the gold electrode (at +0.19 V vs Ag/AgCl), and the magnitude of current is directly proportional to the concentration of hCG in the sample.	Aminophenols	37-48	hypertrichosis 2 (generalised, congenital)	Homo sapiens	212-215
1631900-9	1992	However, p-aminophenol toxicity in vivo is directed toward the S-2 and S-3 segments, which are rich in gamma-glutamyl transpeptidase.	Aminophenols	11-22	gamma-glutamyltransferase 1	Rattus norvegicus	103-132
1631900-11	1992	The aminophenol glutathione S-conjugates formed induce p-aminophenol nephrotoxicity by a pathway dependent on gamma-glutamyl transpeptidase.	Aminophenols	4-15	gamma-glutamyltransferase 1	Rattus norvegicus	110-139
3934671-3	1985	Quinone reductase can be induced in murine Hepa 1c1c7 hepatoma cells and 3T3 embryo fibroblasts by compounds that are chemoprotectors in vivo, including some phenolic antioxidants, azo dyes, aromatic diamines, and aminophenols.	Aminophenols	214-226	crystallin, zeta	Mus musculus	0-17
1353743-0	1992	Effect of aminophenols (5-ASA and 4-ASA) on colonic interleukin-1 generation.	Aminophenols	10-22	interleukin 1 alpha	Homo sapiens	52-65
34709251-5	2021	However, the three complexes show Orbach relaxation under Hdc = 1000 Oe, and 1Py is the in-field SIM with the highest energy barrier among these complexes, with a Ueff value of 358 K. Analysis of ac magnetic data shows that the electron-withdrawing substituents on the phenol rings of the aminophenol ligands, as well as the auxiliary oxygen donors from water ligands, reduce the energy barriers of the complexes, which is attributed to a charge reduction in the coordinating atoms of the aminophenol donor.	Aminophenols	289-300	histidine decarboxylase	Homo sapiens	58-61
34709251-5	2021	However, the three complexes show Orbach relaxation under Hdc = 1000 Oe, and 1Py is the in-field SIM with the highest energy barrier among these complexes, with a Ueff value of 358 K. Analysis of ac magnetic data shows that the electron-withdrawing substituents on the phenol rings of the aminophenol ligands, as well as the auxiliary oxygen donors from water ligands, reduce the energy barriers of the complexes, which is attributed to a charge reduction in the coordinating atoms of the aminophenol donor.	Aminophenols	489-500	histidine decarboxylase	Homo sapiens	58-61
27671344-6	2017	The parent compounds herein presented a certain reactivity concerning oxidation and thiol binding: Unsubstituted aminophenols bound covalently to C159 and C418 of human 5-LO.	Aminophenols	113-125	arachidonate 5-lipoxygenase	Homo sapiens	169-173
923727-0	1977	Comparison of human adult and fetal hemoglobin: aminophenol-induced methemoglobin formation.	Aminophenols	48-59	hemoglobin subunit gamma 2	Homo sapiens	68-81
923727-1	1977	Human fetal hemoglobin was more susceptible to methemoglobin formation in the presence of aminophenols than was adult hemoglobin.	Aminophenols	90-102	hemoglobin subunit gamma 2	Homo sapiens	47-60
6037683-0	1967	The reaction of acetylcholinesterase with diethylphosphoryl esters of quaternary and tertiary aminophenols.	Aminophenols	94-106	acetylcholinesterase (Cartwright blood group)	Homo sapiens	16-36
19867826-10	1914	The formation of methemoglobin by pneumococci probably resembles the formation of methemoglobin by certain chemical substances, such as aminophenol.	Aminophenols	136-147	hemoglobin subunit gamma 2	Homo sapiens	17-30
19867826-10	1914	The formation of methemoglobin by pneumococci probably resembles the formation of methemoglobin by certain chemical substances, such as aminophenol.	Aminophenols	136-147	hemoglobin subunit gamma 2	Homo sapiens	82-95
30399599-0	2019	Aminophenols increase proliferation of thyroid tumor cells by inducing the transcription factor activity of estrogen receptor alpha.	Aminophenols	0-12	estrogen receptor 1	Homo sapiens	108-131
30399599-3	2019	Recently, it was found that ERalpha may also participate in the transformation and progression of thyroid tumors, but its interaction with aminophenols and its function in thyroid tumors is not clear.	Aminophenols	139-151	estrogen receptor 1	Homo sapiens	28-35
30399599-7	2019	Upon administration of aminophenols, the transcription factor activity of ERalpha was significantly increased in BHP10-3 cells, and the recruitment of ERalpha to the promoter of its target gene was increased.	Aminophenols	23-35	estrogen receptor 1	Homo sapiens	74-81
30399599-7	2019	Upon administration of aminophenols, the transcription factor activity of ERalpha was significantly increased in BHP10-3 cells, and the recruitment of ERalpha to the promoter of its target gene was increased.	Aminophenols	23-35	estrogen receptor 1	Homo sapiens	151-158
30399599-9	2019	By discovering that aminophenols induce the onco-promoting activity of ERalpha, our study extends the understanding of the function of aminophenols and suggests that ERalpha is a potential therapeutic target for the treatment of thyroid tumors.	Aminophenols	20-32	estrogen receptor 1	Homo sapiens	71-78
30399599-9	2019	By discovering that aminophenols induce the onco-promoting activity of ERalpha, our study extends the understanding of the function of aminophenols and suggests that ERalpha is a potential therapeutic target for the treatment of thyroid tumors.	Aminophenols	20-32	estrogen receptor 1	Homo sapiens	166-173
30399599-9	2019	By discovering that aminophenols induce the onco-promoting activity of ERalpha, our study extends the understanding of the function of aminophenols and suggests that ERalpha is a potential therapeutic target for the treatment of thyroid tumors.	Aminophenols	135-147	estrogen receptor 1	Homo sapiens	71-78
30399599-9	2019	By discovering that aminophenols induce the onco-promoting activity of ERalpha, our study extends the understanding of the function of aminophenols and suggests that ERalpha is a potential therapeutic target for the treatment of thyroid tumors.	Aminophenols	135-147	estrogen receptor 1	Homo sapiens	166-173
6468841-0	1984	Hydroxylation of deoxy guanosine at the C-8 position by polyphenols and aminophenols in the presence of hydrogen peroxide and ferric ion.	Aminophenols	72-84	homeobox C8	Homo sapiens	40-43
31108565-2	2019	The studied PAR impurities are the genotoxic and nephrotoxic p-amino phenol (PAP) and the hepatotoxic and nephrotoxic chloroacetanilide, while 5-(4-nitrophenyl)-2-furaldehyde is reported to be a mutagenic and carcinogenic degradation product of DNS.	Aminophenols	63-75	jumping translocation breakpoint	Homo sapiens	12-15
30346454-1	2018	Tris(2-(arylamido)-4,6-di-tert-butylphenoxo)molybdenum(vi) complexes (Rap)3Mo can be prepared either from (cycloheptatriene)Mo(CO)3 and the N-aryliminoquinone, or from MoO2(acac)2 and the aminophenol.	Aminophenols	188-199	apolipoprotein A5	Homo sapiens	70-75
28604620-0	2017	Reaction of bis[(2-chlorocarbonyl)phenyl] Diselenide with Phenols, Aminophenols, and Other Amines towards Diphenyl Diselenides with Antimicrobial and Antiviral Properties.	Aminophenols	67-79	Bis protein	Escherichia coli	12-15
28604620-1	2017	A reaction of bis[(2-chlorocarbonyl)phenyl] diselenide with various mono and bisnucleophiles such as aminophenols, phenols, and amines have been studied as a convenient general route to a series of new antimicrobial and antiviral diphenyl diselenides.	Aminophenols	101-113	Bis protein	Escherichia coli	14-17
22707150-1	2013	A new HPLC method was developed for the simultaneous determination of aminophenol isomers by means of a mixed-mode stationary phase containing both SCX and C18 moieties.	Aminophenols	70-81	scleraxis bHLH transcription factor	Homo sapiens	148-151
22707150-1	2013	A new HPLC method was developed for the simultaneous determination of aminophenol isomers by means of a mixed-mode stationary phase containing both SCX and C18 moieties.	Aminophenols	70-81	Bardet-Biedl syndrome 9	Homo sapiens	156-159
22707150-3	2013	The chromatographic conditions for the separation of aminophenols are the stationary phase duet SCX/C18, the mobile phase of aqueous phosphate buffer (pH 4.85):methanol = 85:15 (v/v) delivered with a flow rate of 1 mL/min and a detection at 285 nm.	Aminophenols	53-65	scleraxis bHLH transcription factor	Homo sapiens	96-99
22707150-3	2013	The chromatographic conditions for the separation of aminophenols are the stationary phase duet SCX/C18, the mobile phase of aqueous phosphate buffer (pH 4.85):methanol = 85:15 (v/v) delivered with a flow rate of 1 mL/min and a detection at 285 nm.	Aminophenols	53-65	Bardet-Biedl syndrome 9	Homo sapiens	100-103
17955489-1	2008	Fenretinide, N-(4-hydroxyphenyl)retinamide (4-HPR) is an aminophenol-containing synthetic retinoid derivative of all-trans-retinoic acid, which is a potent chemopreventive and antiproliferative agent against various cancers.	Aminophenols	57-68	haptoglobin-related protein	Homo sapiens	46-49
19726199-5	2009	In the docking model, we confirmed that aromatic ring of Hup A derivatives played the pi-pi stacking against aminophenol residues of AChE, and the structure-activity relationship (SAR) was discussed.	Aminophenols	109-120	acetylcholinesterase (Cartwright blood group)	Homo sapiens	133-137
19726199-5	2009	In the docking model, we confirmed that aromatic ring of Hup A derivatives played the pi-pi stacking against aminophenol residues of AChE, and the structure-activity relationship (SAR) was discussed.	Aminophenols	109-120	sarcosine dehydrogenase	Homo sapiens	147-184
16725328-3	2006	This finding lets us to investigate whether compounds containing alkyl or acyl chains linked to an aminophenol residue as long as 2 and 1, would show activities greater than 2.	Aminophenols	99-110	prostaglandin D2 receptor	Homo sapiens	127-137
12585856-4	2003	This reaction results in high yields and diastereoselectivities and allows the preparation of aminophenols quaternary at the C-1 carbon atom, which cannot be prepared with the methods available till now.	Aminophenols	94-106	heterogeneous nuclear ribonucleoprotein C	Homo sapiens	125-128
11965377-1	2002	A novel potent and selective aminophenol scaffold for fXa inhibitors was developed from a previously reported benzimidazole-based naphthylamidine template.	Aminophenols	29-40	coagulation factor X	Homo sapiens	54-57
11965377-3	2002	Substitution of a propenyl-para-hydroxy-benzamidine group on the aminophenol template produced selective, sub-nanomolar fXa inhibitors.	Aminophenols	65-76	coagulation factor X	Homo sapiens	120-123
12672230-3	2003	To test the robustness of the resulting QSAR model, the synthesis of a series of non-peptide thrombin inhibitors based on arylsuphonyl derivatives of an aminophenol ring linked to a pyridyl-based S1 binding group was undertaken.	Aminophenols	153-164	coagulation factor II, thrombin	Homo sapiens	93-101
12195949-4	2002	The beta-galactosidase label hydrolyses the substrate aminophenyl-beta-galactopyranoside, and the generated aminophenol enters then into a bioelectrocatalytic amplification cycle at the GDH biosensor.	Aminophenols	108-119	galactosidase beta 1	Homo sapiens	4-22
12195949-4	2002	The beta-galactosidase label hydrolyses the substrate aminophenyl-beta-galactopyranoside, and the generated aminophenol enters then into a bioelectrocatalytic amplification cycle at the GDH biosensor.	Aminophenols	108-119	hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase	Homo sapiens	186-189