PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
21733698-3	2011	Compared with tetrahydroisoquinoline-based hydroxamic acids, tyrosine-based hydroxamic acid derivatives exhibited more potent HDAC8 inhibitory activity.	tetrahydroisoquinoline-based hydroxamic acids	14-59	histone deacetylase 8	Homo sapiens	126-131