PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
9314829-6	1997	SR Ca(2+)-uptake assays revealed that the EC50 values for Ca2+ were as follows: 0.32 +/- 0.01 mumol/L in hearts overexpressing monomeric phospholamban, 0.49 +/- 0.05 mumol/L in hearts overexpressing wild-type phospholamban, and 0.26 +/- 0.01 mumol/L in wild-type control mouse hearts.	sr ca(2+)	0-9	phospholamban	Mus musculus	137-150
22493744-10	2012	CONCLUSION/SIGNIFICANCE: Through activation of GHS-R1a, ghrelin and hexarelin produced a positive inotropic effect on ischemic cardiomyocytes and protected them from I/R injury probably by protecting or recovering p-PLB (and therefore SR Ca(2+) content) to allow the maintenance or recovery of normal cardiac contractility.	sr ca(2+)	235-244	growth hormone secretagogue receptor	Mus musculus	47-54
20833651-4	2011	The double-knockout (dKO) mice for PLN and SLN showed increased SERCA pump activity, Ca(2+) transients and SR Ca(2+) load, and developed cardiac hypertrophy.	sr ca(2+)	107-116	phospholamban	Mus musculus	35-38
20833651-4	2011	The double-knockout (dKO) mice for PLN and SLN showed increased SERCA pump activity, Ca(2+) transients and SR Ca(2+) load, and developed cardiac hypertrophy.	sr ca(2+)	107-116	sarcolipin	Mus musculus	43-46
22164205-7	2011	Under voltage clamp, SR Ca(2+) release flux and total SR Ca(2+) release are significantly reduced in CASQ1 null myofibers.	sr ca(2+)	21-30	calsequestrin 1	Mus musculus	101-106
22164205-7	2011	Under voltage clamp, SR Ca(2+) release flux and total SR Ca(2+) release are significantly reduced in CASQ1 null myofibers.	sr ca(2+)	54-63	calsequestrin 1	Mus musculus	101-106
20080988-11	2010	CONCLUSION: The elevation of SR Ca(2+) load--in the absence of beta-adrenergic stimulation--is sufficient to increase the propensity for triggered arrhythmias in RyR2(R4496C+/-) cardiomyocytes.	sr ca(2+)	29-38	ryanodine receptor 2	Homo sapiens	162-166
18390622-8	2008	Ignoring background SR Ca(2+)-leakage in our measurement protocol produces an artifactually high D(CaSR) (>40 microm(2)/s), which may also explain the previous high values.	sr ca(2+)	20-29	calcium-sensing receptor	Rattus norvegicus	99-103
18006473-8	2008	Accordingly, SR Ca(2+) uptake and cardiac function were significantly reduced in SAR-KO mice after TAC.	sr ca(2+)	13-22	sarcalumenin	Mus musculus	81-84
17627988-8	2007	Taken together these results demonstrate that CS1 is essential for the normal development of the SR and its calcium release units and for the storage and release of appropriate amounts of SR Ca(2+).	sr ca(2+)	188-197	ITPR interacting domain containing 2	Mus musculus	46-49
16945967-11	2006	The subsequent addition of FBP (1 mm) partially restored Ca(2+) spark frequency and SR Ca(2+) load.	sr ca(2+)	84-93	fructose-bisphosphatase 1	Homo sapiens	27-30