PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 23306054-1 2013 We have synthesized three analogues of 4-amino-5-fluorohexanoic acids as potential inactivators of gamma-aminobutyric acid aminotransferase (GABA-AT), which were designed to combine the potency of their shorter chain analogue, 4-amino-5-fluoropentanoic acid (AFPA), with the greater enzyme selectivity of the antiepileptic vigabatrin (Sabril ). 4-amino-5-fluorohexanoic acids 39-69 4-aminobutyrate aminotransferase Homo sapiens 99-139 23306054-1 2013 We have synthesized three analogues of 4-amino-5-fluorohexanoic acids as potential inactivators of gamma-aminobutyric acid aminotransferase (GABA-AT), which were designed to combine the potency of their shorter chain analogue, 4-amino-5-fluoropentanoic acid (AFPA), with the greater enzyme selectivity of the antiepileptic vigabatrin (Sabril ). 4-amino-5-fluorohexanoic acids 39-69 4-aminobutyrate aminotransferase Homo sapiens 141-148