PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 35151725-5 2022 Following PCB and OH-PCB exposure, significant changes in mRNA expression of NIS, TPO, and TG were observed. oh-pcb 18-24 thyroid peroxidase Gallus gallus 82-85 16006569-10 2005 In conclusion, glucuronidation activities of UGT1A1, UGT1A6, and UGT2B1 toward OH-PCBs is relative to expression of the isoforms in each tissue, and glucuronidation intensity of the isoforms is relative to the structure of the OH-PCB to be glucuronidated. oh-pcb 79-85 UDP glucuronosyltransferase family 1 member A1 Rattus norvegicus 45-51 16006569-10 2005 In conclusion, glucuronidation activities of UGT1A1, UGT1A6, and UGT2B1 toward OH-PCBs is relative to expression of the isoforms in each tissue, and glucuronidation intensity of the isoforms is relative to the structure of the OH-PCB to be glucuronidated. oh-pcb 79-85 UDP glucuronosyltransferase family 1 member A6 Rattus norvegicus 53-59 16006569-10 2005 In conclusion, glucuronidation activities of UGT1A1, UGT1A6, and UGT2B1 toward OH-PCBs is relative to expression of the isoforms in each tissue, and glucuronidation intensity of the isoforms is relative to the structure of the OH-PCB to be glucuronidated. oh-pcb 79-85 UDP glucuronosyltransferase family 2 member B17 Rattus norvegicus 65-71 11351435-6 2001 Maximum plasma VTG of 0.048 mg/ml in the highest dose (50 mg/kg) of OH-PCB 61 was approximately 100-fold lower than natural estrogens and OH-PCB 30. oh-pcb 68-74 LOC100136735 Oncorhynchus mykiss 15-18 11351435-6 2001 Maximum plasma VTG of 0.048 mg/ml in the highest dose (50 mg/kg) of OH-PCB 61 was approximately 100-fold lower than natural estrogens and OH-PCB 30. oh-pcb 138-144 LOC100136735 Oncorhynchus mykiss 15-18 11351435-10 2001 Differences in plasma VTG induction by OH-PCB 30 and OH-PCB 61 support in vitro predictions that the degree and position of chlorination are important for ER activation. oh-pcb 39-45 LOC100136735 Oncorhynchus mykiss 22-25 11351435-10 2001 Differences in plasma VTG induction by OH-PCB 30 and OH-PCB 61 support in vitro predictions that the degree and position of chlorination are important for ER activation. oh-pcb 53-59 LOC100136735 Oncorhynchus mykiss 22-25 23584369-6 2013 The ability of OH-PCBs to serve as substrates for human cytosolic sulfotransferase 1A1 (hSULT1A1) was assessed by OH-PCB-dependent formation of adenosine-3",5"-diphosphate, an end product of the sulfation reaction. oh-pcb 15-21 sulfotransferase family 1A member 1 Homo sapiens 88-96 23584369-9 2013 All OH-PCB precursors for these sulfates were found to be substrates for hSULT1A1. oh-pcb 4-10 sulfotransferase family 1A member 1 Homo sapiens 73-81 18414928-7 2009 For estrogen receptor beta (ERbeta), the mRNA expression pattern was OH-PCB-metabolite congener-specific. oh-pcb 69-75 estrogen receptor 2a Salmo salar 4-26 17207528-4 2007 Our data show that OH-PCB congeners and EE2, decreased AhRalpha and ARNT transcript levels, and CYP1A1, UGT and GST gene expressions, together with CYP3A gene expression. oh-pcb 19-25 cytochrome P450 3A27 Salmo salar 148-153 20060147-3 2010 The levels of VTG production in hepatocytes of male X. laevis exposed to six kinds of OH-PCB isomers (2"-OH-CB30, 3"-OH-CB30, 4"-OH-CB30, 4"-OH-CB50, 4"-OH-CB61 4"-OH-CB65) were significantly higher as compared to the control group (p<0.05). oh-pcb 86-92 a1-a Xenopus laevis 14-17 20060147-7 2010 The OH-PCB structures of high rank order in the VTG-assay had no chlorine substituted phenolic ring. oh-pcb 4-10 a1-a Xenopus laevis 48-51