PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
23611770-0	2013	Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction.	3,4,5-trisubstituted aminothiophenes	53-89	tumor protein p53	Homo sapiens	107-110
23611770-0	2013	Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction.	3,4,5-trisubstituted aminothiophenes	53-89	MDM2 proto-oncogene	Homo sapiens	111-115
23601819-0	2013	Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction.	3,4,5-trisubstituted aminothiophenes	53-89	tumor protein p53	Homo sapiens	107-110
23601819-0	2013	Design, synthesis and biological evaluation of novel 3,4,5-trisubstituted aminothiophenes as inhibitors of p53-MDM2 interaction.	3,4,5-trisubstituted aminothiophenes	53-89	MDM2 proto-oncogene	Homo sapiens	111-115
23601819-2	2013	A series of 3,4,5-trisubstituted aminothiophenes were designed, synthesized, and evaluated for their p53-MDM2 binding inhibitory potency and anti-proliferation activities against A549 and PC3 tumor cell lines.	3,4,5-trisubstituted aminothiophenes	12-48	tumor protein p53	Homo sapiens	101-104
23601819-2	2013	A series of 3,4,5-trisubstituted aminothiophenes were designed, synthesized, and evaluated for their p53-MDM2 binding inhibitory potency and anti-proliferation activities against A549 and PC3 tumor cell lines.	3,4,5-trisubstituted aminothiophenes	12-48	MDM2 proto-oncogene	Homo sapiens	105-109
23601819-4	2013	Meanwhile, most of the 3,4,5-trisubstituted aminothiophenes displayed better or equivalent anti-proliferation activities against wild-type p53 cell line A549 compared to that of Nutlin-3.	3,4,5-trisubstituted aminothiophenes	23-59	tumor protein p53	Homo sapiens	139-142