PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 18693756-9 2008 Similarly, G1:dimer complex at 20 microM stimulated the rate of release of subfragment 1 bound nucleotide (mant-ADP) only 1.6-fold in comparison to about 9-fold by native F-actin at a concentration of 0.5 microM. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 107-115 actin Oryctolagus cuniculus 173-178 24396733-4 2013 To identify drugs that modulate AMPK activity independent of the canonical ATP-binding pocket found throughout the kinome, we designed a robust fluorescence-based high throughput screening assay biased toward the identification of molecules that bind the regulatory region of AMPK through displacement of MANT-ADP, a fluorescent ADP analog. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 305-313 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 276-280 24396733-7 2013 After validation, we screened 13,120 molecules and identified 3 positive hits that dose-dependently inhibited the protein-bound signal of MANT-ADP in the presence of both full-length AMPK and the truncated "regulatory fragment" of AMPK, which is missing the kinase active site. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 138-146 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 183-187 24396733-7 2013 After validation, we screened 13,120 molecules and identified 3 positive hits that dose-dependently inhibited the protein-bound signal of MANT-ADP in the presence of both full-length AMPK and the truncated "regulatory fragment" of AMPK, which is missing the kinase active site. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 138-146 protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens 231-235 15952789-1 2005 The [Mg(2+)] dependence of ADP binding to myosin V and actomyosin V was measured from the fluorescence of mantADP. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 106-113 myosin VA Homo sapiens 42-50 9454569-6 1998 The rate of mantADP release from the M.K341.mantADP complex increased as a function of tubulin concentration with a second-order rate constant of 11 microM-1 s-1 for K341 binding to the microtubule and reached a maximum rate of mantADP release of 303 s-1. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 12-19 gamma-Tubulin at 23C Drosophila melanogaster 87-94 15247293-5 2004 ATP-dependent Mt.Eg5 dissociation was relatively slow and rate-limiting at 8 s(-1) with mantADP release at 40 s(-1). 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 88-95 kinesin family member 11 Homo sapiens 17-20 9454569-6 1998 The rate of mantADP release from the M.K341.mantADP complex increased as a function of tubulin concentration with a second-order rate constant of 11 microM-1 s-1 for K341 binding to the microtubule and reached a maximum rate of mantADP release of 303 s-1. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 44-51 gamma-Tubulin at 23C Drosophila melanogaster 87-94 9454569-6 1998 The rate of mantADP release from the M.K341.mantADP complex increased as a function of tubulin concentration with a second-order rate constant of 11 microM-1 s-1 for K341 binding to the microtubule and reached a maximum rate of mantADP release of 303 s-1. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 44-51 gamma-Tubulin at 23C Drosophila melanogaster 87-94 7787057-6 1995 A similar degree of protection was also observed for mantATP during steady-state hydrolysis by S1, and for mantADP bound to acto-S1 or to myosin in myofibrils. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 107-114 myosin heavy chain 14 Homo sapiens 138-144 7548087-5 1995 A set of kinetic constants for 20 degrees C 50 mM NaCl is K1 = 2 x 10(4) M-1, k2 = 200 s-1, k3 = 9 s-1, k5 = 0.01 s-1, and K6 = 2 x 10(-5) M. Values of K1 and K6 are estimates for mant-ATP and mant-ADP, respectively. 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 193-201 keratin 1 Homo sapiens 152-161 7982925-2 1994 The 10 S conformation of smooth muscle myosin could be induced by addition of 1-N6-ethenoadenosine or mant ADP plus beryllium fluoride, as well as by mant adenosine 5"-(beta,gamma-iminotriphosphate) (AMPPNP). 3'-O-(N-methylanthraniloyl)adenosine 5'-diphosphate 102-110 myosin heavy chain 14 Homo sapiens 39-45