PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2945903-6	1986	Treatment of striatal membranes with filipine and (NH4)2SO4 produced, as did PLA2 treatment, a rapid decline in [3H]SCH 23390 binding.	Filipin	37-45	phospholipase A2 group IB	Homo sapiens	77-81
20561599-4	2010	SERPINA1 association with monocytes is inhibited by cholesterol depleting/efflux-stimulating agents (nystatin, filipin, MbetaCD (methyl-beta-cyclodextrin) and oxidized low-density lipoprotein (oxLDL) and conversely, enhanced by free cholesterol.	Filipin	111-118	serpin family A member 1	Homo sapiens	0-8
23818521-8	2013	AG1478, an inhibitor of epidermal growth factor receptor tyrosine kinase, the metalloprotease inhibitor batimastat, and methyl-beta-cyclodextrin and filipin, which block lipid raft formation, prevented DCA stimulation of ERK1/2.	Filipin	149-156	mitogen-activated protein kinase 3	Homo sapiens	221-227
3594517-6	1987	Filipin or chlorpromazine might disrupt the interaction between AChR and AChE.	Filipin	0-7	acetylcholinesterase-like	Aplysia californica	73-77
6679334-1	1983	The polyene cholesterol-binding antibiotics filipin and amphotericin B inhibited the binding of cholesterol to steroid-free, soluble adrenocortical cytochrome P-450SCC.	Filipin	44-51	cholesterol side-chain cleavage enzyme, mitochondrial	Bos taurus	148-167
12118012-8	2002	Finally, prevention of the TNF-alpha-stimulated neosynthesis of GD3, cyclosporin A, and latrunculin A or filipin protected sensitized hepatocytes from TNF-alpha-mediated cell death.	Filipin	105-112	tumor necrosis factor	Rattus norvegicus	27-36
17372146-4	2007	The redistribution of PSGL-1 induced by IL-8 was inhibited by cholesterol-perturbing agents such as methyl-beta-cyclodextrin and filipin.	Filipin	129-136	selectin P ligand	Homo sapiens	22-28
17372146-4	2007	The redistribution of PSGL-1 induced by IL-8 was inhibited by cholesterol-perturbing agents such as methyl-beta-cyclodextrin and filipin.	Filipin	129-136	C-X-C motif chemokine ligand 8	Homo sapiens	40-44
18434319-6	2008	In contrast, cholesterol binding agents such as filipin and nystatin and the tyrosine kinase inhibitor genistein dramatically inhibited Dsg3 internalization.	Filipin	48-55	desmoglein 3	Homo sapiens	136-140
12118012-8	2002	Finally, prevention of the TNF-alpha-stimulated neosynthesis of GD3, cyclosporin A, and latrunculin A or filipin protected sensitized hepatocytes from TNF-alpha-mediated cell death.	Filipin	105-112	tumor necrosis factor	Rattus norvegicus	151-160
11799176-2	2002	In agreement with these results, we found that CD4 and the associated Lck tyrosine kinase of peripheral blood mononuclear cells and H9 leukemic T cells were selectively and highly enriched in a low-density lipid fraction that was resistant at 0 degrees C to the neutral detergent Triton X-100 but was disrupted by extraction of cholesterol with filipin or methyl-beta-cyclodextrin.	Filipin	345-352	CD4 molecule	Homo sapiens	47-50