PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 24583775-3 2014 Among the series studied, the 4-(2-aminoethyl)amino-pyrrolopyridine derivative, 2j, exhibited a significant 24.7-fold JAK1/JAK2 selectivity along with reasonable inhibitory activity against JAK1 (IC50=2.2 microM). 4-(2-aminoethyl)amino-pyrrolopyridine 30-67 Janus kinase 1 Homo sapiens 118-122 24583775-3 2014 Among the series studied, the 4-(2-aminoethyl)amino-pyrrolopyridine derivative, 2j, exhibited a significant 24.7-fold JAK1/JAK2 selectivity along with reasonable inhibitory activity against JAK1 (IC50=2.2 microM). 4-(2-aminoethyl)amino-pyrrolopyridine 30-67 Janus kinase 2 Homo sapiens 123-127 24583775-3 2014 Among the series studied, the 4-(2-aminoethyl)amino-pyrrolopyridine derivative, 2j, exhibited a significant 24.7-fold JAK1/JAK2 selectivity along with reasonable inhibitory activity against JAK1 (IC50=2.2 microM). 4-(2-aminoethyl)amino-pyrrolopyridine 30-67 Janus kinase 1 Homo sapiens 190-194