PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22648561-7	2012	In addition, the N-glucuronide (2-amino) conjugate (P37.7) and two metabolites (P38.2 and P39) that resulted from the cleavage about the aminoethanol group linking the hydroxyquinolinone and diethylindane moieties had a combined contribution of 12.5%.	n-glucuronide	17-30	nucleoporin 37	Homo sapiens	52-55
8118934-4	1994	Ring-hydroxylated metabolites and the primary N-glucuronide of 4-ABP accounted for 8% and 4%, respectively.	n-glucuronide	46-59	amine oxidase, copper containing 1	Rattus norvegicus	65-68
29610665-9	2018	Simulations evaluating isolated UGT1A4 induction predicted increased midazolam N-glucuronide exposure (~4-fold) with minimal reductions in parent midazolam exposure (~10%).	n-glucuronide	79-92	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	32-38
29610665-10	2018	Simulations accounting for simultaneous induction of both CYP3A4 and UGT1A4 predicted a ~10-fold decrease in parent midazolam exposure with only a ~2-fold decrease in midazolam N-glucuronide metabolite exposure.	n-glucuronide	177-190	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	58-64
29610665-10	2018	Simulations accounting for simultaneous induction of both CYP3A4 and UGT1A4 predicted a ~10-fold decrease in parent midazolam exposure with only a ~2-fold decrease in midazolam N-glucuronide metabolite exposure.	n-glucuronide	177-190	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	69-75
26512042-10	2016	The Km and Vmax values describing the formation of the N-glucuronide in HLM or rUGT1A1 were 2.7 microM or 0.75 microM and 8.9 or 8.3 pmol min(-1) mg(-1), respectively.	n-glucuronide	55-68	oxysterol binding protein 2	Homo sapiens	72-75
26512042-10	2016	The Km and Vmax values describing the formation of the N-glucuronide in HLM or rUGT1A1 were 2.7 microM or 0.75 microM and 8.9 or 8.3 pmol min(-1) mg(-1), respectively.	n-glucuronide	55-68	UDP glucuronosyltransferase family 1 member A1	Rattus norvegicus	79-86
8142014-7	1994	Two of nine TCCs induced by the N-glucuronide of N-hydroxy-2-aminofluorene were found to have p53 mutations.	n-glucuronide	32-45	Wistar clone pR53P1 p53 pseudogene	Rattus norvegicus	94-97
3103910-9	1987	The results show that N-glucuronide formation can be catalyzed by UDPGT isoforms which also catalyze the formation of O-glucuronides.	n-glucuronide	22-35	UDP glycosyltransferase 2 family, polypeptide B	Rattus norvegicus	66-71
3707623-0	1986	Structural assignment of an N-glucuronide metabolite of the phenylethanolamine N-methyltransferase (PNMT) inhibitor 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide by 15N-NMR.	n-glucuronide	28-41	phenylethanolamine N-methyltransferase	Homo sapiens	60-98
3707623-0	1986	Structural assignment of an N-glucuronide metabolite of the phenylethanolamine N-methyltransferase (PNMT) inhibitor 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide by 15N-NMR.	n-glucuronide	28-41	phenylethanolamine N-methyltransferase	Homo sapiens	100-104
29691239-5	2018	Chemical inhibition (using specific chemical inhibitor Ko143) and biologic inhibition [using specific short hairpin RNA of breast cancer resistance protein (BCRP)] resulted in a significant reduction in efflux of N-glucuronide.	n-glucuronide	213-226	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	123-155
29691239-5	2018	Chemical inhibition (using specific chemical inhibitor Ko143) and biologic inhibition [using specific short hairpin RNA of breast cancer resistance protein (BCRP)] resulted in a significant reduction in efflux of N-glucuronide.	n-glucuronide	213-226	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	157-161
23704698-5	2013	Diastereomers of O-glucuronide (SMG1 and SMG3) and a N-glucuronide (SMG2) were identified by incubation of M-1 with HLMs in the presence of uridine 5"-diphosphoglucuronic acid (UDPGA), and their structures were confirmed by nuclear magnetic resonance and mass spectrometry analyses.	n-glucuronide	53-66	UPF1 RNA helicase and ATPase	Homo sapiens	68-72
22648561-7	2012	In addition, the N-glucuronide (2-amino) conjugate (P37.7) and two metabolites (P38.2 and P39) that resulted from the cleavage about the aminoethanol group linking the hydroxyquinolinone and diethylindane moieties had a combined contribution of 12.5%.	n-glucuronide	17-30	cyclin dependent kinase 5 regulatory subunit 2	Homo sapiens	90-93
21511943-10	2011	The four oxidative metabolites were formed by multiple human P450 enzymes, and N-glucuronide was formed by UGT1A3 and UGT2B7.	n-glucuronide	79-92	UDP glucuronosyltransferase family 1 member A3	Homo sapiens	107-113
21511943-10	2011	The four oxidative metabolites were formed by multiple human P450 enzymes, and N-glucuronide was formed by UGT1A3 and UGT2B7.	n-glucuronide	79-92	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	118-124
19845433-4	2009	Lamotrigine (LTG) is primarily metabolized to its N-glucuronide (LTGG) by hUGT1A4.	n-glucuronide	50-63	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	74-81
17567733-5	2007	The N-glucuronide conjugate (M-9) was found as the major metabolite and the oxidized form of the 2-methylimidazole moiety (M-2) and the ring-cleavage form (M-4) were detected as the minor metabolites in the 2-h plasma, but M-4 was found to be the main component in the 12-h plasma.	n-glucuronide	4-17	eukaryotic translation initiation factor 3 subunit K	Homo sapiens	29-32
17484517-4	2007	The production of the N-glucuronide metabolite was only catalysed by recombinant UGT1A4.	n-glucuronide	22-35	UDP glucuronosyltransferase family 1 member A4	Homo sapiens	81-87
15100177-10	2004	This N-glucuronide represents a fully characterized amide N-glucuronide, and glucuronidation at the nitrogen represents a newly identified conjugation reaction for UGT2B7.	n-glucuronide	5-18	UDP glucuronosyltransferase family 2 member B7	Homo sapiens	164-170
21155392-0	2010	Identification of the UDP-glucuronosyltransferase responsible for bucolome N-glucuronide formation in rats.	n-glucuronide	75-88	UDP glycosyltransferase 2 family, polypeptide B	Rattus norvegicus	22-49
21155392-7	2010	The results suggest that UGT 1A1 is primarily responsible for BCP N-glucuronide formation in rats.	n-glucuronide	66-79	UDP glucuronosyltransferase family 1 member A1	Rattus norvegicus	25-32
18256203-10	2008	The N-glucuronide derivative was found in human hepatocytes incubated under control conditions but also in the presence of the well known CYP3A4 inhibitor, ketoconazole.	n-glucuronide	4-17	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	138-144
16713428-5	2006	The rates of metabolism for UGT1A9, human liver microsomes, and UGT1A1 were 200, 100, and 100 pmol N-glucuronide per minute per milligram of protein, respectively.	n-glucuronide	99-112	UDP glucuronosyltransferase family 1 member A9	Homo sapiens	28-34
16713428-5	2006	The rates of metabolism for UGT1A9, human liver microsomes, and UGT1A1 were 200, 100, and 100 pmol N-glucuronide per minute per milligram of protein, respectively.	n-glucuronide	99-112	UDP glucuronosyltransferase family 1 member A1	Homo sapiens	64-70