PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 24491228-6 2014 21-hydroxy-pregnenolone was identified as a new substrate, and overall low activity toward pregnanes could be related to the increased potency of 7-hydroxy derivatives produced by CYP7B1. 21-hydroxypregnenolone 0-23 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 180-186 22975514-0 2012 Inhibition of human steroidogenic cytochrome P450 c17 by 21-hydroxypregnenolone and related steroid hormones. 21-hydroxypregnenolone 57-79 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 34-53 22975514-4 2012 Nonetheless, 21-hydroxypregnenolone exhibited competitive inhibition of progesterone 17alpha-hydroxylation activity by CYP17 with a Ki value of 36.4 microM. 21-hydroxypregnenolone 13-35 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 119-124