PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22276424-4	2011	Pre-incubation of the isolated mitochondria with nicotine prevented from dissipation of their membrane potential stimulated with 0.8 microM CaCl2 depending on the dose, and this effect was strengthened by the antagonist of alpha7 nicotinic receptors (alpha7 nAChR) methyllicaconitine.	methyllicaconitine	265-283	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	223-263
22359587-8	2012	alpha7-specific antagonist methyllicaconitine (50 nM) did not affect Ca(2+) accumulation in mitochondria but attenuated the effects of agonists on cytochrome c release.	methyllicaconitine	27-45	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	0-6
19583978-8	2009	In addition, clothianidin-induced currents were completely blocked by methyllicaconitine suggesting that (1) clothianidin acted as a specific agonist of nAChR subtypes and (2) a small proportion of receptors blocked by MLA was insensitive to alpha-bungarotoxin.	methyllicaconitine	70-88	cholinergic receptor nicotinic alpha 4 subunit	Homo sapiens	153-158
21146628-6	2011	Inhibition of alpha7 and alpha9(alpha10) nAChRs with methyllicaconitine resulted in considerable augmentation of CD40-mediated B lymphocyte proliferation in cells of all genotypes; stimulation of alpha4beta2 nAChRs with epibatidine increased the IgM-mediated proliferation of the wild-type and alpha7(-/-), but not beta2(-/-) cells.	methyllicaconitine	53-71	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	14-39
21146628-6	2011	Inhibition of alpha7 and alpha9(alpha10) nAChRs with methyllicaconitine resulted in considerable augmentation of CD40-mediated B lymphocyte proliferation in cells of all genotypes; stimulation of alpha4beta2 nAChRs with epibatidine increased the IgM-mediated proliferation of the wild-type and alpha7(-/-), but not beta2(-/-) cells.	methyllicaconitine	53-71	CD40 antigen	Mus musculus	113-117
21146628-6	2011	Inhibition of alpha7 and alpha9(alpha10) nAChRs with methyllicaconitine resulted in considerable augmentation of CD40-mediated B lymphocyte proliferation in cells of all genotypes; stimulation of alpha4beta2 nAChRs with epibatidine increased the IgM-mediated proliferation of the wild-type and alpha7(-/-), but not beta2(-/-) cells.	methyllicaconitine	53-71	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	14-20
20595621-4	2010	Nicotine"s effect on hyperexcitability of inflamed neurons was blocked in the presence of an alpha(7)-nicotinic acetylcholine receptor (nAChR) antagonist, methyllicaconitine, while choline, the alpha(7)-nAChR agonist, induced a similar effect to that of nicotine.	methyllicaconitine	155-173	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	93-134
20595621-4	2010	Nicotine"s effect on hyperexcitability of inflamed neurons was blocked in the presence of an alpha(7)-nicotinic acetylcholine receptor (nAChR) antagonist, methyllicaconitine, while choline, the alpha(7)-nAChR agonist, induced a similar effect to that of nicotine.	methyllicaconitine	155-173	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	136-141
20595621-4	2010	Nicotine"s effect on hyperexcitability of inflamed neurons was blocked in the presence of an alpha(7)-nicotinic acetylcholine receptor (nAChR) antagonist, methyllicaconitine, while choline, the alpha(7)-nAChR agonist, induced a similar effect to that of nicotine.	methyllicaconitine	155-173	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	194-208
20387628-6	2009	Anti-CD40-induced B lymphocyte proliferation studied by [3H]thymidine incorporation was increased upon alpha7 nAChR inhibition with methyllicaconitine, choline or antibiotic gentamicin, as well as in the presence of the inhibitor of acetylcholine synthesis hemicholine-3.	methyllicaconitine	132-150	CD40 antigen	Mus musculus	5-9
20387628-6	2009	Anti-CD40-induced B lymphocyte proliferation studied by [3H]thymidine incorporation was increased upon alpha7 nAChR inhibition with methyllicaconitine, choline or antibiotic gentamicin, as well as in the presence of the inhibitor of acetylcholine synthesis hemicholine-3.	methyllicaconitine	132-150	cholinergic receptor, nicotinic, alpha polypeptide 7	Mus musculus	103-115