PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 21042414-1 2010 5-Androstene-3beta,7beta,17beta-triol (beta-AET), an active metabolite of dehydroepiandrosterone (DHEA), reversed glucocorticoid (GC)-induced suppression of IL-6, IL-8 and osteoprotegerin production by human osteoblast-like MG-63 cells and promoted osteoblast differentiation of human mesenchymal stem cells (MSCs). 7beta 19-24 interleukin 6 Homo sapiens 157-161 25436707-1 2012 Abstract Successive action of cytochrome P450-7B1 (CYP7B1) and 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) on 3beta-hydroxysteroids such as DHEA and epiandrosterone leads to the production of cytoprotective 7beta-hydroxylated derivatives. 7beta 220-225 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 30-49 25436707-1 2012 Abstract Successive action of cytochrome P450-7B1 (CYP7B1) and 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) on 3beta-hydroxysteroids such as DHEA and epiandrosterone leads to the production of cytoprotective 7beta-hydroxylated derivatives. 7beta 220-225 cytochrome P450 family 7 subfamily B member 1 Homo sapiens 51-57 25436707-1 2012 Abstract Successive action of cytochrome P450-7B1 (CYP7B1) and 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) on 3beta-hydroxysteroids such as DHEA and epiandrosterone leads to the production of cytoprotective 7beta-hydroxylated derivatives. 7beta 220-225 RNA, U1 small nuclear 1 Homo sapiens 63-118 21042414-1 2010 5-Androstene-3beta,7beta,17beta-triol (beta-AET), an active metabolite of dehydroepiandrosterone (DHEA), reversed glucocorticoid (GC)-induced suppression of IL-6, IL-8 and osteoprotegerin production by human osteoblast-like MG-63 cells and promoted osteoblast differentiation of human mesenchymal stem cells (MSCs). 7beta 19-24 C-X-C motif chemokine ligand 8 Homo sapiens 163-167 21042414-1 2010 5-Androstene-3beta,7beta,17beta-triol (beta-AET), an active metabolite of dehydroepiandrosterone (DHEA), reversed glucocorticoid (GC)-induced suppression of IL-6, IL-8 and osteoprotegerin production by human osteoblast-like MG-63 cells and promoted osteoblast differentiation of human mesenchymal stem cells (MSCs). 7beta 19-24 TNF receptor superfamily member 11b Homo sapiens 172-187 25961967-2 2010 These 7alpha-hydroxysteroids are in turn transformed into 7beta-hydroxylated epimers by 11beta-hydroxysteroid dehydrogenase type 1 in the tissue. 7beta 58-63 hydroxysteroid 11-beta dehydrogenase 1 Rattus norvegicus 88-130 17825335-0 2007 5Alpha-androstane-3beta,7alpha,17beta-triol and 5alpha-androstane-3beta,7beta,17beta-triol as substrates for the human 11beta-hydroxysteroid dehydrogenase type 1. 7beta 32-37 hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens 119-161 11585742-3 2001 p53 codons containing methylated CpG sequences are preferential targets for formation of adducts by (+/-) anti-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE). 7beta 111-116 tumor protein p53 Homo sapiens 0-3 9108075-2 1997 We have previously mapped the distribution of (+/-) anti-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy -7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) adducts along the human P53 gene [Denissenko, M. F., Pao, A., Tang, M.-s. & Pfeifer, G. P. (1996) Science 274, 430-432]. 7beta 57-62 tumor protein p53 Homo sapiens 167-170 25092323-9 2014 In vivo, administration of 7beta, 27-OHC in mice enhanced IL-17 production. 7beta 27-32 interleukin 17A Mus musculus 58-63