PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 9161849-8 1997 Lipid peroxidation, assessed as thiobarbituric acid-reactive substances, was 40% lower in nkef-B-transfected cells compared with vector-only-transfected cells. substance S 61-71 peroxiredoxin 2 Homo sapiens 90-96 9357164-9 1997 Again the sensitivity of the response to CCl4 was enhanced remarkably in hepatocytes isolated from phenobarbital- pretreated rats; LDH leakage increased by 3-fold and thio-barbituric acid reactive substances by 25-fold. substance S 197-207 C-C motif chemokine ligand 4 Rattus norvegicus 41-45 16377630-4 2006 The urinary excretion of isoprostanes was increased in CuZn-SOD knockout mice, and plasma thiobarbituric acid-reactive substances levels were elevated in EC-SOD knockout mice. substance S 119-129 superoxide dismutase 3, extracellular Mus musculus 154-160 15897607-3 2005 Macrophages from sPLA2 transgenic mice have 2.5 times increased rates of LDL oxidation (thiobarbituric acid-reactive substances formation) in vitro (59 +/- 5 vs. 24 +/- 4 nmol malondialdehyde/mg protein; P < 0.001) dependent on functional 12/15-lipoxygenase (12/15-LO). substance S 117-127 phospholipase A2, group IIA (platelets, synovial fluid) Mus musculus 17-22 11404242-7 2001 The levels of thiobarbituric acid-reactive substances and 8-hydroxy-2"-deoxyguanosine in the lung tissue of CFTR-KO mice were significantly increased compared with those in WT mice. substance S 43-53 cystic fibrosis transmembrane conductance regulator Mus musculus 108-112 9299412-1 1997 We investigated whether liver expression of the peroxisome proliferator-activated receptor alpha (PPAR alpha) gene is related to the plasma thiobarbituric acid-reactive substance (TBARS) level, as well as to plasma cholesterol (TC) level and plasma triglyceride (TG) level in rats fed a high fat chow containing a variety of fatty acids. substance S 169-178 peroxisome proliferator activated receptor alpha Rattus norvegicus 48-96 9299412-1 1997 We investigated whether liver expression of the peroxisome proliferator-activated receptor alpha (PPAR alpha) gene is related to the plasma thiobarbituric acid-reactive substance (TBARS) level, as well as to plasma cholesterol (TC) level and plasma triglyceride (TG) level in rats fed a high fat chow containing a variety of fatty acids. substance S 169-178 peroxisome proliferator activated receptor alpha Rattus norvegicus 98-108 9256507-0 1997 A substance P (neurokinin-1) receptor mutant carboxyl-terminally truncated to resemble a naturally occurring receptor isoform displays enhanced responsiveness and resistance to desensitization. substance S 2-11 tachykinin receptor 1 Rattus norvegicus 15-37 24197033-1 1994 The prothrombin time of the normal human pooled plasma was shortened by Aldrich humic acid well water humic substances and lignin at final concentrations ranging from 5 x 10(-3) mg mL(-1) to 5 x 10(-2) mg mL(-1), with a maxmum effect at 1 x 10(-2) mg mL(-1). substance S 108-118 coagulation factor II, thrombin Homo sapiens 4-15 9035732-1 1996 To study possible correlation between plasma transferrin content and level of 2-thiobarbituric acid-reactive substances (malonic dialdehyde (MDA)) in the liver of mice, these parameters were assayed during brombenzol-induced lipid peroxidation and when this process was inhibited by zinc-metallothionein (zinc-MT). substance S 109-119 transferrin Mus musculus 45-56 8765690-10 1996 The trap substance N-t-butyl-a-phenylnitrone (BNP) also diminished LC-CL more effectively than LM-CL. substance S 9-18 natriuretic peptide B Rattus norvegicus 46-49 34743024-0 2022 Predicting the Effects of Per- and Polyfluoroalkyl Substance Mixtures on Peroxisome Proliferator-Activated Receptor Alpha Activity in Vitro. substance S 51-60 peroxisome proliferator activated receptor alpha Homo sapiens 73-121 8135659-5 1993 The CCl4-induced rise in thiobarbituric acid-reactive substances, an index of lipid peroxidation, was not affected by ascorbate feeding. substance S 54-64 chemokine (C-C motif) ligand 4 Mus musculus 4-8 32308750-6 2020 SiO2-PIL + could combine with negatively charged extracellular polymeric substances (EPS) and create holes to remove the biofilm barrier. substance S 73-83 serpin family A member 2 (gene/pseudogene) Homo sapiens 5-8 4882528-0 1968 [Gastrin and gastrin-like substance]. substance S 26-35 gastrin Homo sapiens 13-20 34910874-0 2022 Long-Term Trends of Per- and Polyfluoroalkyl Substances (PFAS) in Suspended Particular Matter from German Rivers Using the Direct Total Oxidizable Precursor (dTOP) Assay. substance S 45-55 phosphoribosylformylglycinamidine synthase Homo sapiens 57-61 34604686-10 2021 Furthermore, 200 mug mL-1 Cd maximally and significantly (p <= 0.05) reduced the synthesis of 2,3-dihydroxybenzoic acid (2,3-DHBA), salicylic acid (SA), 1-aminocyclopropane 1-carboxylate (ACC) deaminase, and extra polymeric substances (EPSs) of E. cloacae MC9 by 80, 81, 77, and 59%, respectively, over control. substance S 224-234 L1 cell adhesion molecule Mus musculus 21-25 32479937-1 2020 The goal of this study was to reveal how the chemical modification, succinylation in this case, of the wide-pore serum-albumin-based cryogels affects on their osmotic characteristics (swelling extent), biodegradability and ability to be loaded with the bactericide substance - dioxidine, as well as on its release. substance S 265-276 albumin Homo sapiens 113-126 26875733-7 2016 Additionally, the significant decreases in the total thiol level, activities of catalase and glutathione-S-transferase were accompanied with significant increases in the generation of reactive oxygen and nitrogen species and thiobarbituric acid reactive substances in flies exposed to manganese alone. substance S 254-264 Catalase Drosophila melanogaster 80-88 26424786-6 2016 Accordingly, INT-777 decreased mitochondrial H2O2 generation and increased the activity of SOD2, which associated with decreased urinary levels of H2O2 and thiobarbituric acid reactive substances. substance S 185-195 superoxide dismutase 2, mitochondrial Mus musculus 91-95 25298524-5 2014 ANG II induced hypertension and proteinuria, reduced NO oxidation products (NOx), and increased oxidative stress (NADPH oxidase activity, thiobarbituric acid-reactive substances, and 8-isoprostane excretion) and plasma ADMA. substance S 167-177 angiotensinogen Rattus norvegicus 0-6 21890508-7 2011 This induction of HO-1 led to significantly improved liver function, reduced apoptosis and thiobarbituric acid reactive substances of the liver, and decreased inflammatory cytokine production. substance S 120-130 heme oxygenase 1 Rattus norvegicus 18-22 22776436-11 2012 The levels of thiobarbituric acid-reactive substances that were increased by CCl4 were brought back to control levels by the administration of SAME and silymarin. substance S 43-53 C-C motif chemokine ligand 4 Rattus norvegicus 77-81 24716135-9 2012 In the presence of CCl4, APE decreased hepatic thiobarbituric acid-reactive substances production and plasma aspartate aminotransferase and alanine aminotransferase activities. substance S 76-86 C-C motif chemokine ligand 4 Rattus norvegicus 19-23 24716135-9 2012 In the presence of CCl4, APE decreased hepatic thiobarbituric acid-reactive substances production and plasma aspartate aminotransferase and alanine aminotransferase activities. substance S 76-86 apurinic/apyrimidinic endodeoxyribonuclease 1 Rattus norvegicus 25-28 24995855-6 2014 Growth hormone also suppressed the accumulation of oxidative stress marker, thiobarbituric acid-reactive substances, in the epididymal fat and enhanced the gene expression of anti-oxidant enzymes. substance S 105-115 growth hormone Mus musculus 0-14 23646304-5 2013 RESULTS: The liver of CCl4 induced not treated group showed that the induction with CCl4, significantly (P<0.05) increased thiobarbituric acid reactive substance (TBARS) and significantly (P<0.05) decreased superoxide dismutase (SOD) and catalase (CAT). substance S 155-164 C-C motif chemokine ligand 4 Rattus norvegicus 22-26 23646304-5 2013 RESULTS: The liver of CCl4 induced not treated group showed that the induction with CCl4, significantly (P<0.05) increased thiobarbituric acid reactive substance (TBARS) and significantly (P<0.05) decreased superoxide dismutase (SOD) and catalase (CAT). substance S 155-164 C-C motif chemokine ligand 4 Rattus norvegicus 84-88 21673366-7 2011 Injection of ET-1 alone showed a significant (P<0.001) increase in thiobarbituric acid reactive substances (TBARS) and hydrogen peroxide (H(2)O(2)) level as well as a decrease (P<0.01) in GSH level and GSH/GSSG ratio (P<0.02). substance S 99-109 endothelin 1 Rattus norvegicus 13-17 17543459-9 2007 Further, simultaneous leptin treatment along with ethanol showed protection against ethanol mediated cellular damage as indicated by significantly decreased levels of reactive oxygen species (ROS) and thiobarbituric acid reactive substances (TBARS) and significantly increased levels of reactive nitrogen species (RNS), reduced glutathione (GSH) and elevated activities of superoxide dismutase (SOD) and catalase (CAT). substance S 230-240 leptin Homo sapiens 22-28