PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
23852644-7	2013	TMCA increased the activation of glutamic acid decarboxylase (GAD) and the expressions of gamma-subunit of GABAA receptors in the cerebellar granule cells.	3,4,5-trimethoxycinnamic acid	0-4	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	Mus musculus	107-112
25445378-5	2015	Furthermore, a reduction in expression of SC1, a target of DeltaFosB, in the nucleus accumbens of mice subjected to restraint stress was significantly reversed by TMCA (50 mg/kg) treatment.	3,4,5-trimethoxycinnamic acid	163-167	spinal cord QTL 1	Mus musculus	42-45
30632088-8	2019	Moreover, the expression levels of pNR1and pERK in the frontal cortex of mice and cultured cortical neurons were diminished by TMCA.	3,4,5-trimethoxycinnamic acid	127-131	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	43-47
30632088-10	2019	Interestingly, morphine-induced elevations of FosB/DeltaFosB+ cells were suppressed by TMCA (50, 100 mg/kg) in the nucleus accumbens sub-shell region of mice.	3,4,5-trimethoxycinnamic acid	87-91	FBJ osteosarcoma oncogene B	Mus musculus	46-50
23121934-4	2013	Most of 3,4,5-trimethoxycinnamic acid derivatives were found to have high affinity to 5-HT(1A) receptor.	3,4,5-trimethoxycinnamic acid	8-37	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	86-103
23121934-8	2013	Interestingly, the pERK levels were increased by the 3,4,5-trimethoxycinnamic acid derivatives and the derivatives-mediated changes in pERK levels were blocked by the WAY 100635.	3,4,5-trimethoxycinnamic acid	53-82	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	19-23
23121934-8	2013	Interestingly, the pERK levels were increased by the 3,4,5-trimethoxycinnamic acid derivatives and the derivatives-mediated changes in pERK levels were blocked by the WAY 100635.	3,4,5-trimethoxycinnamic acid	53-82	eukaryotic translation initiation factor 2 alpha kinase 3	Mus musculus	135-139
23121934-9	2013	These results suggested that new synthetic 3,4,5-trimethoxycinnamic acid derivatives have a potential antinarcotic effect through acting as a 5-HT(1A) receptor agonist in mice.	3,4,5-trimethoxycinnamic acid	43-72	5-hydroxytryptamine (serotonin) receptor 1A	Mus musculus	142-159
15305046-3	2004	In the present study, we investigate the effects of TMCA on the stress induced with repeated cold exposure or intracerebroventricular injection of corticotrophin-releasing hormone (CRH).	3,4,5-trimethoxycinnamic acid	52-56	corticotropin releasing hormone	Rattus norvegicus	181-184
15305046-5	2004	The intracerebroventricular injection of CRH significantly augmented the content of norepinephrine (NE) in locus coeruleus (LC) of rats, which was significantly suppressed by the intracerebroventricular injection of TMCA.	3,4,5-trimethoxycinnamic acid	216-220	corticotropin releasing hormone	Rattus norvegicus	41-44
34903851-6	2022	Interestingly, we demonstrate that TmcA can specifically modulate the DNA-binding activity of H-NS, a nucleoid-associated protein, by catalysis of Khib at K121.	3,4,5-trimethoxycinnamic acid	35-39	H-NS	Escherichia coli	94-98
33866021-8	2021	Nevertheless, by RNAseq we detected a downregulation of metabolic pathways in the livers of Cldn3-/- young and aged mice as well as a decrease in lipid content and a weakened biliary-barrier for primary bile acids, such as TCA, TCDCA and TMCA.	3,4,5-trimethoxycinnamic acid	238-242	claudin 3	Mus musculus	92-97