PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 25636869-3 2015 Angustidine (2), nauclefine (3), angustine (4), angustoline (6) and harmane (7) showed higher BChE inhibiting potency compared to galanthamine. angustine 33-42 butyrylcholinesterase Homo sapiens 94-98 23261030-4 2013 In addition, the monoterpene indole alkaloids (MIAs) angustine, vallesiachotamine lactone, E-vallesiachotamine and Z-vallesiachotamine inhibited BChE and MAO-A with IC(50) values ranging from 3.47 to 14 muM for BChE inhibition and from 0.85 to 2.14 muM for MAO-A inhibition. angustine 53-62 butyrylcholinesterase Homo sapiens 145-149 23261030-4 2013 In addition, the monoterpene indole alkaloids (MIAs) angustine, vallesiachotamine lactone, E-vallesiachotamine and Z-vallesiachotamine inhibited BChE and MAO-A with IC(50) values ranging from 3.47 to 14 muM for BChE inhibition and from 0.85 to 2.14 muM for MAO-A inhibition. angustine 53-62 monoamine oxidase A Homo sapiens 154-159 23261030-5 2013 Among the tested MIAs, angustine is able to inhibit MAO-A in a reversible and competitive way while the three vallesiachotamine-like alkaloids display a time-dependent inhibition on this target. angustine 23-32 monoamine oxidase A Homo sapiens 52-57