PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3517475-6 1986 10 and 20 mg BAY o 1248 not only reduced the increases in blood glucose and serum insulin after breakfast, but also after lunch (10 mg). emiglitate 13-23 insulin Homo sapiens 82-89 8625892-3 1996 We report here, with a combined in vitro and in vivo approach, that selective inhibition of islet lysosomal glycogenolytic acid glucan-1,4-alpha-glucosidase activity by the long-acting 1-deoxynojirimycin derivative emiglitate induces a profound suppression of nutrient-induced insulin release. emiglitate 215-225 sucrase isomaltase (alpha-glucosidase) Mus musculus 139-156 1815967-0 1991 Inhibition of sucrose- and starch-induced glycaemic and hormonal responses by the alpha-glucosidase inhibitor emiglitate (BAY o 1248) in healthy volunteers. emiglitate 122-132 sucrase-isomaltase Homo sapiens 82-99 3520133-1 1986 BAYo1248 and BAYm1099 are two new alpha-glucosidase inhibitors. emiglitate 0-8 sucrase-isomaltase Homo sapiens 34-51 2962844-7 1987 The inhibition of lactase activity was stronger by Bay-m-1099 (Ki = 4.9 X 10(-6) M) than by Bay-o-1248 (Ki = 6.7 X 10(-5) M). emiglitate 92-102 lactase Rattus norvegicus 18-25 3100764-0 1987 Chronic effects of an alpha-glucosidase inhibitor (Bay o 1248) on intestinal disaccharidase activity in normal and diabetic mice. emiglitate 51-61 sucrase isomaltase (alpha-glucosidase) Mus musculus 22-39