PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
25491917-3	2015	TfR1 is not directly engaged in the intestinal absorption of free iron, and iron uptake by DMT1 is attenuated by ferristatin II treatment.	ferristatin II	113-127	transferrin receptor	Homo sapiens	0-4
25491917-3	2015	TfR1 is not directly engaged in the intestinal absorption of free iron, and iron uptake by DMT1 is attenuated by ferristatin II treatment.	ferristatin II	113-127	doublesex and mab-3 related transcription factor 1	Homo sapiens	91-95
35215911-3	2022	We used ferristatin II to induce the degradation of TfR1 on the surface of Vero cells and to study the consequences of such treatment on the viability of the cells and the replication of SARS-CoV-2.	ferristatin II	8-22	transferrin receptor	Homo sapiens	52-56
23894616-4	2013	While TfR1 constitutively traffics through clathrin-mediated endocytosis, with or without ligand, the presence of Tf blocked ferristatin II induced degradation of TfR1.	ferristatin II	125-139	transferrin receptor	Rattus norvegicus	163-167
35143157-2	2022	To further identify more potent ferroptosis inhibitors and effective targets for treating TBI, our study aims at investigating the effects of TfR1 on ferroptosis in a mouse TBI model using ferristatin II (an iron uptake and TfR1 inhibitor).	ferristatin II	189-203	transferrin receptor	Mus musculus	142-146
35143157-4	2022	In vivo, ferristatin II administration reduced the expression of TfR1 at 12 h after TBI, and immunofluorescence experiments further confirmed that this decreased TfR1-positive cells were neurons.	ferristatin II	9-23	transferrin receptor	Mus musculus	65-69
35143157-4	2022	In vivo, ferristatin II administration reduced the expression of TfR1 at 12 h after TBI, and immunofluorescence experiments further confirmed that this decreased TfR1-positive cells were neurons.	ferristatin II	9-23	transferrin receptor	Mus musculus	162-166
35215911-5	2022	According to confocal microscopy data, the distribution of the labeled transferrin and receptor-binding domain (RBD) of Spike protein is significantly affected by the 18h pretreatment with 100 microM ferristatin II in culture medium.	ferristatin II	200-214	surface glycoprotein	Severe acute respiratory syndrome coronavirus 2	120-125
35215911-9	2022	We hypothesize that ferristatin II blocks the TfR1-mediated SARS-CoV-2 host cell entry; however, further studies are needed to elucidate the full mechanisms of this virus inhibition, including the effect of ferristatin II on other SARS-CoV-2 receptors, such as ACE2, Neuropilin-1 and CD147.	ferristatin II	20-34	transferrin receptor	Homo sapiens	46-50
35215911-9	2022	We hypothesize that ferristatin II blocks the TfR1-mediated SARS-CoV-2 host cell entry; however, further studies are needed to elucidate the full mechanisms of this virus inhibition, including the effect of ferristatin II on other SARS-CoV-2 receptors, such as ACE2, Neuropilin-1 and CD147.	ferristatin II	20-34	angiotensin converting enzyme 2	Homo sapiens	261-265
35215911-9	2022	We hypothesize that ferristatin II blocks the TfR1-mediated SARS-CoV-2 host cell entry; however, further studies are needed to elucidate the full mechanisms of this virus inhibition, including the effect of ferristatin II on other SARS-CoV-2 receptors, such as ACE2, Neuropilin-1 and CD147.	ferristatin II	20-34	neuropilin 1	Homo sapiens	267-279
35215911-9	2022	We hypothesize that ferristatin II blocks the TfR1-mediated SARS-CoV-2 host cell entry; however, further studies are needed to elucidate the full mechanisms of this virus inhibition, including the effect of ferristatin II on other SARS-CoV-2 receptors, such as ACE2, Neuropilin-1 and CD147.	ferristatin II	20-34	basigin (Ok blood group)	Homo sapiens	284-289
35215911-9	2022	We hypothesize that ferristatin II blocks the TfR1-mediated SARS-CoV-2 host cell entry; however, further studies are needed to elucidate the full mechanisms of this virus inhibition, including the effect of ferristatin II on other SARS-CoV-2 receptors, such as ACE2, Neuropilin-1 and CD147.	ferristatin II	207-221	transferrin receptor	Homo sapiens	46-50