PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
19150360-5	2009	When expressed in yeast cells lacking the endogenous TFIIS, Arabidopsis TFIIS partially complements the sensitivity of mutant cells to the nucleotide analog 6-azauridine, which is a typical characteristic of transcript elongation factors.	Azauridine	157-169	transcript elongation factor IIS	Arabidopsis thaliana	53-58
19452525-0	2009	Recognition of acyl donors by lipase CAL-B in the acylation of 6-azauridine.	Azauridine	63-75	calbindin 1	Homo sapiens	37-42
19452525-1	2009	CAL-B-catalyzed synthesis of different 5"-O-monoester derivatives of 6-azauridine via a one-step highly regioselective enzymatic acylation route was successfully performed for the first time.	Azauridine	69-81	calbindin 1	Homo sapiens	0-5
19150360-5	2009	When expressed in yeast cells lacking the endogenous TFIIS, Arabidopsis TFIIS partially complements the sensitivity of mutant cells to the nucleotide analog 6-azauridine, which is a typical characteristic of transcript elongation factors.	Azauridine	157-169	transcript elongation factor IIS	Arabidopsis thaliana	72-77
2479415-2	1989	Monophosphates of both AZUrd and PF competitively inhibit orotidine-5"-monophosphate decarboxylase (ODCase) activity of the UMP synthase multifunctional enzyme.	Azauridine	23-28	uridine monophosphate synthetase	Mus musculus	124-136
7482031-9	1995	The monofunctional OPRT protein was less stable than the ODC protein at 45 degrees C. Growth of transfected cells in 6-azauridine resulted in striking increases in activity and temperature stability for the monofunctional ODC protein.	Azauridine	117-129	uridine monophosphate synthetase	Homo sapiens	19-23
1710119-6	1991	In contrast, pyrazofurin and 6-azauridine, two nucleoside analogues that are assumed to interfere with OMP decarboxylase, another enzyme involved in the biosynthesis of pyrimidine ribonucleotides, potentiate the cytocidal activity of Ce-Cyd.	Azauridine	29-41	olfactory marker protein	Homo sapiens	103-106
1873380-6	1991	Assays of hypoxanthine phosphoribosyltransferase (HPRT) activity in lysates of four-cell embryos determined that the drugs 6-mercapto-9-(tetrahydro-2-furyl)-purine (MPTF) and 6-mercaptopurine (6-MP), but not 6-azauridine (6-AzaU), prevented salvage of hypoxanthine.	Azauridine	208-220	hypoxanthine guanine phosphoribosyl transferase	Mus musculus	50-54
1873380-6	1991	Assays of hypoxanthine phosphoribosyltransferase (HPRT) activity in lysates of four-cell embryos determined that the drugs 6-mercapto-9-(tetrahydro-2-furyl)-purine (MPTF) and 6-mercaptopurine (6-MP), but not 6-azauridine (6-AzaU), prevented salvage of hypoxanthine.	Azauridine	222-228	hypoxanthine guanine phosphoribosyl transferase	Mus musculus	50-54
33799444-0	2021	6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway.	Azauridine	0-12	tumor protein p53	Homo sapiens	57-60
33799444-0	2021	6-Azauridine Induces Autophagy-Mediated Cell Death via a p53- and AMPK-Dependent Pathway.	Azauridine	0-12	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	66-70
33799444-8	2021	In addition, we demonstrated that the cytotoxic effect of 6-AZA was dependent on AMPK and p53.	Azauridine	58-63	protein kinase AMP-activated catalytic subunit alpha 1	Homo sapiens	81-85
33799444-8	2021	In addition, we demonstrated that the cytotoxic effect of 6-AZA was dependent on AMPK and p53.	Azauridine	58-63	tumor protein p53	Homo sapiens	90-93
2475503-5	1989	Growth of deficient cells in 6-azauridine leads to an increase in UMP synthase protein and its two enzymatic activities via a decreased rate of proteolytic degradation of UMP synthase.	Azauridine	29-41	uridine monophosphate synthetase	Homo sapiens	66-78
2475503-5	1989	Growth of deficient cells in 6-azauridine leads to an increase in UMP synthase protein and its two enzymatic activities via a decreased rate of proteolytic degradation of UMP synthase.	Azauridine	29-41	uridine monophosphate synthetase	Homo sapiens	171-183
2475503-6	1989	UMP synthase in extracts from deficient cells is more readily denatured by heat and is stabilized after growth of cells in 6-azauridine.	Azauridine	123-135	uridine monophosphate synthetase	Homo sapiens	0-12
35542-2	1979	The inhibition of dihydro-orotase (E 3.5.2.3) and dihydroorotate (DHO) dehydrogenase (dihydro-orotate oxidase, EC 1.3.3.1) by cellular orotate (OA) in Ehrlich ascites cells was studied by measuring the accumulation of the intermediates of de novo pyrimidine biosynthesis at various times after the addition of 6-azauridine to the culture medium.	Azauridine	310-322	dihydroorotate dehydrogenase	Mus musculus	86-109
2435724-5	1987	The consequences of incubation with actinomycin D, cycloheximide, dibutyryl cyclic AMP, and 6-azauridine on the flux across CTP synthetase and on NTP pools differed considerably between wild type and mutant cells.	Azauridine	92-104	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	Mus musculus	124-127
6835435-1	1983	Some pyrimidine analogues--especially 6-azauridine and 5-azacytidine at a final concentration of 1 mmol dm-3--significantly depressed adenosine deaminase activity isolated and purified from bovine heart.	Azauridine	38-50	adenosine deaminase	Bos taurus	134-153
20227960-2	1980	Uridine and its analogs, 3-deazauridine, 5-bromodeoxyuridine, 5-fluorodeoxyuridine and 6-azauridine, were found to competitively inhibit cytidine deaminase; the most potent inhibitor was 3-deazauridine (K(i) = 1.9 x 10(-5) M).	Azauridine	87-99	cytidine deaminase	Homo sapiens	137-155
27919709-8	2017	The screen discovered 6-azauridine and finasteride as potential anti-ZIKV inhibitors with EC50 levels of 3.18 and 9.85 muM for MR766, respectively.	Azauridine	22-34	latexin	Homo sapiens	119-122