PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 25897175-2 2015 Cytochrome P450 2B6 (CYP2B6) mediates clinical methadone clearance and metabolic inactivation via N-demethylation to 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP). 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine 117-161 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 0-19 25897175-2 2015 Cytochrome P450 2B6 (CYP2B6) mediates clinical methadone clearance and metabolic inactivation via N-demethylation to 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP). 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine 117-161 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 21-27 23298862-2 2013 Methadone metabolism clinically occurs primarily by N-demethylation to 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP), catalyzed predominantly by CYP2B6. 2-ethyl-1,5-dimethyl-3,3-diphenylpyrrolidine 71-115 cytochrome P450 family 2 subfamily B member 6 Homo sapiens 151-157