PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
20562004-5	2010	Pre-treatment of the cells with atRA resulted in enhanced apical excretion of B[a]P-3-sulfate, a phase II metabolite of B[a]P. Gene expression analysis revealed that the Breast Cancer Resistance Protein (BCRP), an ABC-transporter known to be involved in B[a]P-3-sulfate excretion, was strongly stimulated already at low concentrations of atRA.	3-sulfate	84-93	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	204-208
31099308-0	2020	Bindings of PPARgamma ligand-binding domain with 5-cholesten-3beta, 25-diol, 3-sulfate: accurate prediction by molecular simulation.	3-sulfate	77-86	peroxisome proliferator activated receptor gamma	Homo sapiens	12-21
20562004-5	2010	Pre-treatment of the cells with atRA resulted in enhanced apical excretion of B[a]P-3-sulfate, a phase II metabolite of B[a]P. Gene expression analysis revealed that the Breast Cancer Resistance Protein (BCRP), an ABC-transporter known to be involved in B[a]P-3-sulfate excretion, was strongly stimulated already at low concentrations of atRA.	3-sulfate	260-269	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	170-202
20562004-5	2010	Pre-treatment of the cells with atRA resulted in enhanced apical excretion of B[a]P-3-sulfate, a phase II metabolite of B[a]P. Gene expression analysis revealed that the Breast Cancer Resistance Protein (BCRP), an ABC-transporter known to be involved in B[a]P-3-sulfate excretion, was strongly stimulated already at low concentrations of atRA.	3-sulfate	260-269	ATP binding cassette subfamily G member 2 (Junior blood group)	Homo sapiens	204-208
20610891-5	2010	The Michaelis-Menten constant for estrone 3-sulfate uptake by OATP4C1 was 26.6+/-4.9 microM.	3-sulfate	42-51	solute carrier organic anion transporter family member 4C1	Homo sapiens	62-69
20527891-2	2010	Two metabolites showed activity in these assays; the 3-sulfate exhibited QR1 induction, DPPH free radical scavenging, and COX-1 and COX-2 inhibitory activities and the 4"-sulfate inhibited NFkappaB induction, as well as COX-1 and COX-2 activities.	3-sulfate	53-62	NAD(P)H quinone dehydrogenase 1	Homo sapiens	73-76
20527891-2	2010	Two metabolites showed activity in these assays; the 3-sulfate exhibited QR1 induction, DPPH free radical scavenging, and COX-1 and COX-2 inhibitory activities and the 4"-sulfate inhibited NFkappaB induction, as well as COX-1 and COX-2 activities.	3-sulfate	53-62	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	122-127
20527891-2	2010	Two metabolites showed activity in these assays; the 3-sulfate exhibited QR1 induction, DPPH free radical scavenging, and COX-1 and COX-2 inhibitory activities and the 4"-sulfate inhibited NFkappaB induction, as well as COX-1 and COX-2 activities.	3-sulfate	53-62	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	132-137
20527891-2	2010	Two metabolites showed activity in these assays; the 3-sulfate exhibited QR1 induction, DPPH free radical scavenging, and COX-1 and COX-2 inhibitory activities and the 4"-sulfate inhibited NFkappaB induction, as well as COX-1 and COX-2 activities.	3-sulfate	53-62	mitochondrially encoded cytochrome c oxidase I	Homo sapiens	220-225
20527891-2	2010	Two metabolites showed activity in these assays; the 3-sulfate exhibited QR1 induction, DPPH free radical scavenging, and COX-1 and COX-2 inhibitory activities and the 4"-sulfate inhibited NFkappaB induction, as well as COX-1 and COX-2 activities.	3-sulfate	53-62	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	230-235
20610891-9	2010	The estimated IC(50) value of digoxin for OATP4C1-mediated estrone 3-sulfate transport was 119 microM.	3-sulfate	67-76	solute carrier organic anion transporter family member 4C1	Homo sapiens	42-49
10644724-0	2000	Cholesterol 3-sulfate interferes with cornified envelope assembly by diverting transglutaminase 1 activity from the formation of cross-links and esters to the hydrolysis of glutamine.	3-sulfate	12-21	transglutaminase 1	Homo sapiens	79-97
17545668-8	2007	Cholesterol 3-sulfate and sulfatide co-existed with galectin-4 in detergent-insoluble fractions of porcine esophagus and intestine, respectively.	3-sulfate	12-21	galectin 4	Homo sapiens	52-62
16359813-3	2006	We here identify the integral membrane protein ABCC11 (multidrug resistance protein 8) as an ATP-dependent efflux pump for steroid sulfates, including dehydroepiandrosterone 3-sulfate, and localize it to axons of the human CNS and peripheral nervous system.	3-sulfate	174-183	ATP binding cassette subfamily C member 11	Homo sapiens	47-53
16359813-10	2006	Inside-out plasma membrane vesicles containing recombinant ABCC11 mediated ATP-dependent transport of dehydroepiandrosterone 3-sulfate with a Km value of 21 microM.	3-sulfate	125-134	ATP binding cassette subfamily C member 11	Homo sapiens	59-65
12719432-5	2003	None of the proteins elicited a transport signal when expressed individually in oocytes; however, all nine OSTalpha-OSTbeta combinations (i.e. OSTalpha-OSTbeta pairs from human, mouse, or skate) generated robust estrone 3-sulfate transport activity.	3-sulfate	220-229	solute carrier family 51 subunit alpha	Homo sapiens	107-115
19589875-8	2009	The 3-sulfate as a monosulfate or as the disulfate was hydrolyzed by human placental steroid sulfatase, whereas the 24-sulfate was resistant.	3-sulfate	4-13	arylsulfatase family member H	Homo sapiens	93-102
11102445-11	2001	Direct transport studies using [(3)H]estrone 3-sulfate confirmed that the conjugated estrogen could be efficiently transported (K(m) = 0.73 microm, V(max) = 440 pmol mg(-)1 protein min(-)1), but only in the presence of either GSH or the nonreducing alkyl derivative, S-methyl GSH.	3-sulfate	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	181-188
2317215-2	1990	Bacterial as well as pig liver arylsulfatase A and B demonstrated a higher substrate turnover of epinephrine-4-sulfate, norepinephrine-4-sulfate and dopamine-4-sulfate as compared to the 3-sulfate isomers.	3-sulfate	187-196	arylsulfatase A	Sus scrofa	31-46
10746151-1	1999	We have investigated the serum concentration of 16-dehydropregnenolone (3 beta-hydroxy-5,16-pregnadien-20-one) 3-sulfate (16-DHPS) in the umbilical artery (U.A.	3-sulfate	111-120	deoxyhypusine synthase	Homo sapiens	125-129
9644715-4	1998	CYP3A7 expressed in TN-5 cells was capable of metabolizing testosterone, cortisol and dehydroepiandrosterone 3-sulfate as well as dehydroepiandrosterone.	3-sulfate	109-118	cytochrome P450 family 3 subfamily A member 7	Homo sapiens	0-6
1878883-4	1991	spectroscopy showed that sulfation occurred selectively at C-3 of residue 7, to give a new polymer that may be described as a 3-sulfate analog of heparin.	3-sulfate	126-135	complement C3	Homo sapiens	59-62
2281511-5	1990	In addition, the 3-sulfate of 5 alpha-pregnane-3 alpha,20 alpha-diol became hydroxylated at C-21.	3-sulfate	17-26	TBL1X/Y related 1	Homo sapiens	92-96
2281511-14	1990	The 3-sulfate of 5 alpha-pregnane-3 alpha,20 alpha-diol was hydroxylated at C-21.	3-sulfate	4-13	TBL1X/Y related 1	Homo sapiens	76-80