PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 26227779-2 2015 N-(4-Chlorophenyl)-2-(piperazin-1-yl)quinazolin-4-amine (5o) has a Ki value of 14.04 +- 0.21 nM, with a selectivity more than 10,000 fold over 5-HT1A receptors (D1 and D2-like receptors). 5o 57-59 5-hydroxytryptamine receptor 1A Homo sapiens 143-149 35436756-9 2022 5o induces cell apoptosis in a dose-dependent manner through PI3K/Akt/FoxO1 and NF-kappaB signaling pathways. 5o 0-2 AKT serine/threonine kinase 1 Homo sapiens 66-69 35436756-9 2022 5o induces cell apoptosis in a dose-dependent manner through PI3K/Akt/FoxO1 and NF-kappaB signaling pathways. 5o 0-2 forkhead box O1 Homo sapiens 70-75 35436756-13 2022 This study reveals that 5o is a promising therapeutic agent against CRC as a novel GRP94 inhibition. 5o 24-26 heat shock protein 90 beta family member 1 Homo sapiens 83-88