PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 27081794-5 2016 By using immunofluorescence labeling and a confocal laser scanning microscope, we found that trivalent lanthanum [La(III)], an REE ion, affected the expression of CaM in endocytosis. Lanthanum 103-112 calmodulin 1 Homo sapiens 163-166 26613180-1 2016 In this study, a novel lanthanum-loaded magnetic cationic hydrogel (MCH-La) was synthesized for fluoride adsorption from drinking water. Lanthanum 23-32 pro-melanin concentrating hormone Homo sapiens 68-71 27088967-1 2016 Lanthanum complexes [(L)LaX] (X = N(SiMe3)2, O(i)Pr , BH4) supported by a ferrocene-based (OSSO)-type ligand LH2 were synthesized and characterized by elemental analysis, NMR spectroscopy and cyclic voltammetry. Lanthanum 0-9 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 Homo sapiens 109-112 30090262-0 2015 In vivo study and thermodynamic investigation of two lanthanum complexes, La(dpp)3 and La(XT), for the treatment of bone resorption disorders. Lanthanum 53-62 dipeptidyl peptidase 3 Homo sapiens 74-82 25763053-4 2014 The effect of the las transfer was capable to increase the cytokines TNFalpha and IL10 expression in Hec-1B cells line infected with these transformed mutants (in eight log scale of folding change RNA expression). Lanthanum 18-21 tumor necrosis factor Homo sapiens 69-77 26209160-3 2015 In the present study, we propose that the levels of proliferation and apoptosis related microRNAs (miRNAs), let-7a and miR-34a, which mediate the apoptosis of cervical cancer cells, can be affected by the lanthanum ion. Lanthanum 205-214 microRNA 34a Homo sapiens 119-126 25763053-4 2014 The effect of the las transfer was capable to increase the cytokines TNFalpha and IL10 expression in Hec-1B cells line infected with these transformed mutants (in eight log scale of folding change RNA expression). Lanthanum 18-21 interleukin 10 Homo sapiens 82-86 24851926-5 2015 We discuss the local environment of lanthanum ions in molten LaF3-LiF-Li2O and compare the results to those with the LaF3-LiF-CaO system. Lanthanum 36-45 LIF interleukin 6 family cytokine Homo sapiens 66-69 25033298-2 2014 The N-terminal domain (ShhN) is also assigned to the group of LAS proteins (LAS = Lysostaphin type enzymes, D-Ala-D-Ala metalloproteases, Sonic Hedgehog), of which all members harbor a structurally well-defined Zn2+ center; however, it is remarkable that ShhN so far is the only LAS member without proven peptidase activity. Lanthanum 62-65 sonic hedgehog signaling molecule Homo sapiens 138-152 25037694-11 2014 In addition, as compared with control LAs, testosterone-treated LAs expressed more androgen receptor, beta1-adrenergic receptor, and Cav 1.2 and less G protein-coupled receptor kinase-2 and Kv 4.2. Lanthanum 64-67 androgen receptor Oryctolagus cuniculus 83-100 25037694-11 2014 In addition, as compared with control LAs, testosterone-treated LAs expressed more androgen receptor, beta1-adrenergic receptor, and Cav 1.2 and less G protein-coupled receptor kinase-2 and Kv 4.2. Lanthanum 64-67 beta-1 adrenergic receptor Oryctolagus cuniculus 102-140 25037694-11 2014 In addition, as compared with control LAs, testosterone-treated LAs expressed more androgen receptor, beta1-adrenergic receptor, and Cav 1.2 and less G protein-coupled receptor kinase-2 and Kv 4.2. Lanthanum 64-67 beta-adrenergic receptor kinase 1 Oryctolagus cuniculus 150-185 23993414-13 2014 In the number of cells that stained positive for BMP-2, the LAS group was significantly larger than that in the AS group after 1 (P < 0.0001) and 2 weeks (P = 0.0113). Lanthanum 60-63 bone morphogenetic protein 2 Oryctolagus cuniculus 49-54 24384318-2 2014 RAB (adapted biomass) was operated in two stages: Stage I, with standard LAS (13.2 mg L(-1)); and Stage II, in which the standard LAS was replaced by diluted laundry wastewater according to the LAS concentration (11.2 mg L(-1)). Lanthanum 73-76 ArfGAP with FG repeats 1 Homo sapiens 0-3 24384318-2 2014 RAB (adapted biomass) was operated in two stages: Stage I, with standard LAS (13.2 mg L(-1)); and Stage II, in which the standard LAS was replaced by diluted laundry wastewater according to the LAS concentration (11.2 mg L(-1)). Lanthanum 130-133 ArfGAP with FG repeats 1 Homo sapiens 0-3 24384318-2 2014 RAB (adapted biomass) was operated in two stages: Stage I, with standard LAS (13.2 mg L(-1)); and Stage II, in which the standard LAS was replaced by diluted laundry wastewater according to the LAS concentration (11.2 mg L(-1)). Lanthanum 130-133 ArfGAP with FG repeats 1 Homo sapiens 0-3 23748361-12 2013 ARKO LAs expressed higher amounts of Ca(2+)/calmodulin-dependent protein kinase II, Na(+)/Ca(2+) exchanger, and phosphorylated phospholamban (Ser-16/Thr-17 site) and less Cav1.2, Kir2.1, Kir3.1, and Kv7.1 than WT LAs. Lanthanum 5-8 cytochrome P450, family 19, subfamily a, polypeptide 1 Mus musculus 0-4 24151010-5 2013 In the case of the largest metal center, lanthanum, this C-H bond activation could be suppressed at -35 C, thereby leading to the isolation of [(Cp(NMe2))La(AlMe4)2], which contains an intramolecularly coordinated amino group. Lanthanum 41-50 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 149-153 23307042-8 2013 The significantly lower rate in the LAL group than the LAS group was caused by bacterial resistance to LVFX. Lanthanum 55-58 lipase A, lysosomal acid type Homo sapiens 36-39 23695775-3 2013 With the larger lanthanum cations, the metallic coordination spheres are completed with two terminal axial triflate counter-anions to give [La2(L10)3(CF3SO3)2]4+. Lanthanum 16-25 immunoglobulin kappa variable 3-7 (non-functional) Homo sapiens 144-147 23748361-12 2013 ARKO LAs expressed higher amounts of Ca(2+)/calmodulin-dependent protein kinase II, Na(+)/Ca(2+) exchanger, and phosphorylated phospholamban (Ser-16/Thr-17 site) and less Cav1.2, Kir2.1, Kir3.1, and Kv7.1 than WT LAs. Lanthanum 5-8 calcium channel, voltage-dependent, L type, alpha 1C subunit Mus musculus 171-177 23748361-12 2013 ARKO LAs expressed higher amounts of Ca(2+)/calmodulin-dependent protein kinase II, Na(+)/Ca(2+) exchanger, and phosphorylated phospholamban (Ser-16/Thr-17 site) and less Cav1.2, Kir2.1, Kir3.1, and Kv7.1 than WT LAs. Lanthanum 5-8 potassium inwardly-rectifying channel, subfamily J, member 2 Mus musculus 179-185 23748361-12 2013 ARKO LAs expressed higher amounts of Ca(2+)/calmodulin-dependent protein kinase II, Na(+)/Ca(2+) exchanger, and phosphorylated phospholamban (Ser-16/Thr-17 site) and less Cav1.2, Kir2.1, Kir3.1, and Kv7.1 than WT LAs. Lanthanum 5-8 potassium inwardly-rectifying channel, subfamily J, member 3 Mus musculus 187-193 23557666-9 2013 Results from the PCR analysis showed that the virus recoveries of the lanthanum-based method were 20.6% (+-2.9%) and 19.5% (+-3.4%) for MS2 and adenovirus, respectively, while no adenovirus could be detected through the NanoCeram- and 1MDS-based direct filtration. Lanthanum 70-79 MS2 Homo sapiens 136-139 23338853-0 2013 Lanthanum induced primary neuronal apoptosis through mitochondrial dysfunction modulated by Ca2+ and Bcl-2 family. Lanthanum 0-9 BCL2 apoptosis regulator Homo sapiens 101-106 23338853-7 2013 Our results demonstrated that toxicity of lanthanum in cortical neurons perhaps partly attributed to enhanced mitochondrial apoptosis due to mitochondrial dysfunction modulated by Ca(2+) and Bcl-2 family. Lanthanum 42-51 BCL2 apoptosis regulator Homo sapiens 191-196 23831939-0 2013 Spin injection and detection in lanthanum- and niobium-doped SrTiO3 using the Hanle technique. Lanthanum 32-41 spindlin 1 Homo sapiens 0-4 23445348-7 2013 The stronger binding of Ca(2+) to LAS results in the addition of Ca(2+) having a much greater impact on the self-assembly of R1/LAS and R2/LAS mixtures. Lanthanum 34-37 CD1b molecule Homo sapiens 125-138 23325290-3 2013 In sharp contrast, if we take advantage of the high catalytic activities of La(Oi-Pr)(3), La(OTf)(3), and La(NO(3))(3) as ligand-free catalysts, ligand-assisted or additive-enhanced lanthanum(III) catalysts can be highly effective acid-base combined catalysts in transesterification. Lanthanum 182-191 POU class 5 homeobox 1 Homo sapiens 90-99 23078771-2 2012 On the contrary, the related enzyme glutathione reductase is not inhibited by lanthanum ions even at relatively high concentrations. Lanthanum 78-87 glutathione-disulfide reductase Homo sapiens 36-57 22407468-0 2012 In utero and lactational lanthanum exposure induces olfactory dysfunction associated with downregulation of betaIII-tubulin and olfactory marker protein in young rats. Lanthanum 25-34 olfactory marker protein Rattus norvegicus 128-152 22407468-9 2012 Developmental lanthanum exposure could impair olfaction, and this deficit may be attributed to the downregulation of betaIII-tubulin and OMP in the OE. Lanthanum 14-23 olfactory marker protein Rattus norvegicus 137-140 22668831-7 2012 The activity could be enhanced by lanthanum or rosiglitazone, known stimulators of TRPC5 and TRPC5-containing channels. Lanthanum 34-43 transient receptor potential cation channel subfamily C member 5 Homo sapiens 83-88 22668831-7 2012 The activity could be enhanced by lanthanum or rosiglitazone, known stimulators of TRPC5 and TRPC5-containing channels. Lanthanum 34-43 transient receptor potential cation channel subfamily C member 5 Homo sapiens 93-98 20680507-0 2011 The suppressive effects of lanthanum on the production of inflammatory mediators in mice challenged by LPS. Lanthanum 27-36 toll-like receptor 4 Mus musculus 103-106 21989390-7 2011 Further experiments revealed that all types of LAs activated cell survival-associated kinase Akt, and an inhibitor of PI3K, LY294002, suppressed both LA-induced upregulation of NQO1 and cell protection against BSO. Lanthanum 47-50 AKT serine/threonine kinase 1 Homo sapiens 93-96 21989390-7 2011 Further experiments revealed that all types of LAs activated cell survival-associated kinase Akt, and an inhibitor of PI3K, LY294002, suppressed both LA-induced upregulation of NQO1 and cell protection against BSO. Lanthanum 47-50 NAD(P)H quinone dehydrogenase 1 Homo sapiens 177-181 21753024-9 2011 The effects of CCK were suppressed by the generic, nonselective cationic channel blockers, 2-aminoethyldiphenyl borate and flufenamic acid, but potentiated by gadolinium ion and lanthanum ion at 100 muM. Lanthanum 178-187 cholecystokinin Homo sapiens 15-18 21364497-2 2011 Recent reports have demonstrated that the coadministration of capsaicin with a local anesthetic (LA) at the rat sciatic nerve elicits a prolonged nociceptive-selective nerve block, suggesting that activation of the TRPV1 receptor may allow LAs to enter the nerve through the TRPV1 pore. Lanthanum 240-243 transient receptor potential cation channel, subfamily V, member 1 Rattus norvegicus 215-220 21457165-2 2011 N-(3-oxododecanoyl) homoserine lactone (3-oxo-C12-HSL) is used in the las quorum-sensing system in Pseudomonas aeruginosa, which is an opportunistic pathogen that causes many human diseases. Lanthanum 70-73 lipase E, hormone sensitive type Rattus norvegicus 50-53 21285322-8 2011 Lanthanum, a TRPC-4,-5 channel activator, potentiated the leptin-induced inward current by 170%. Lanthanum 0-9 short transient receptor potential channel 4 Cavia porcellus 13-19 21695898-0 2011 [Effects of lanthanum on the phosphorylation of cAMP response element binding protein and expression of immediate early genes in the hippocampal CA3 area of rats]. Lanthanum 12-21 cAMP responsive element binding protein 1 Rattus norvegicus 48-85 21695898-0 2011 [Effects of lanthanum on the phosphorylation of cAMP response element binding protein and expression of immediate early genes in the hippocampal CA3 area of rats]. Lanthanum 12-21 carbonic anhydrase 3 Rattus norvegicus 145-148 21285322-8 2011 Lanthanum, a TRPC-4,-5 channel activator, potentiated the leptin-induced inward current by 170%. Lanthanum 0-9 leptin Cavia porcellus 58-64 20233740-6 2010 Lanthanum half effective concentration (EC(50)) was 77.28 nM, lower than the 2.30 mM obtained for calcium, supporting the concept that this metal is a strong agonist of the CaSR. Lanthanum 0-9 calcium sensing receptor Homo sapiens 173-177 21177771-6 2011 The spike activity diminished at half effective concentration values for the two phases of 117 nM and 763 muM LaCl(3) corresponding to 16 ng/ml and 10.6 mug/ml lanthanum, respectively. Lanthanum 160-169 latexin Homo sapiens 106-109 21146870-8 2011 (45)Ca uptake experiments showed that cadmium, lanthanum and gadolinium were also highly efficient inhibitors of TRPV6-mediated calcium influx at higher micromolar concentrations. Lanthanum 47-56 transient receptor potential cation channel subfamily V member 6 Homo sapiens 113-118 20233740-0 2010 Lanthanum activates calcium-sensing receptor and enhances sensitivity to calcium. Lanthanum 0-9 calcium sensing receptor Homo sapiens 20-44 20233740-7 2010 Moreover, lanthanum was also able to enhance CaSR sensitivity to calcium. Lanthanum 10-19 calcium sensing receptor Homo sapiens 45-49 20233740-1 2010 BACKGROUND: The aim of this study was to investigate whether nanomolar concentrations of lanthanum could influence the calcium-sensing receptor (CaSR) response. Lanthanum 89-98 calcium sensing receptor Homo sapiens 119-143 20233740-1 2010 BACKGROUND: The aim of this study was to investigate whether nanomolar concentrations of lanthanum could influence the calcium-sensing receptor (CaSR) response. Lanthanum 89-98 calcium sensing receptor Homo sapiens 145-149 20233740-8 2010 The presence of 1 nM LaCl(3) significantly left-shifted the CaSR response curve, changing the EC(50) value for calcium from 2.30 mM (calcium alone) to 1.26 mM (calcium + 1 nM lanthanum). Lanthanum 175-184 calcium sensing receptor Homo sapiens 60-64 20233740-2 2010 METHODS: Embryonic kidney (HEK-293) cells transiently transfected with the human CaSR were used to test the ability of lanthanum to activate the CaSR, either alone or in combination with calcium. Lanthanum 119-128 calcium sensing receptor Homo sapiens 145-149 20233740-9 2010 The parathyroid glands cultured with lanthanum showed a trend to secrete less PTH compared to the control glands: 1.51 +/- 0.23 (control), 0.91 +/- 0.17 (La 100 nM) and 1.04 +/- 0.18 (La 400 nM) [(pg/h)/(pg/h), mean +/- SEM] (ANOVA P = 0.0145). Lanthanum 37-46 parathyroid hormone Homo sapiens 78-81 20233740-11 2010 CONCLUSIONS: These in vitro findings demonstrate that lanthanum, at nanomolar concentrations, is an agonist of the CaSR able to activate it in the absence of calcium. Lanthanum 54-63 calcium sensing receptor Homo sapiens 115-119 20390293-5 2010 TRPC5 activity could be evoked by carbachol acting at muscarinic receptors, lanthanum, or a reducing agent. Lanthanum 76-85 transient receptor potential cation channel subfamily C member 5 Homo sapiens 0-5 20470901-8 2010 In addition, activation of BK(Ca) channels by C-type natriuretic peptide caused endothelial-dependent vasodilation that was blocked by iberiotoxin, L-NAME, and lanthanum. Lanthanum 160-169 potassium calcium-activated channel subfamily M alpha 1 Rattus norvegicus 27-33 20470901-8 2010 In addition, activation of BK(Ca) channels by C-type natriuretic peptide caused endothelial-dependent vasodilation that was blocked by iberiotoxin, L-NAME, and lanthanum. Lanthanum 160-169 natriuretic peptide C Rattus norvegicus 46-72 19818767-8 2010 Permeability to lanthanum and [14C] mannitol was lower in CFBE41o- and in 16HBE14o- cells exposed to CFTR(inh)-172, compared to untreated 16HBE14o- and CFBE41o-pCep4 cells, respectively. Lanthanum 16-25 CF transmembrane conductance regulator Homo sapiens 101-114 20233211-5 2010 Genistein and lanthanum activated TRPC5 channels synergistically. Lanthanum 14-23 transient receptor potential cation channel subfamily C member 5 Homo sapiens 34-39 20107083-5 2010 Also, lanthanum (La(3+)) and intracellular Ca(2+) potentiated the effects of leptin. Lanthanum 6-15 leptin Mus musculus 77-83 19816179-2 2010 RECENT FINDINGS: A variety of beta2-agonists with long half-lives, also called ultra long-acting beta2-agonists (ultra-LABAs; indacaterol, carmoterol, milveterol, GSK-642444, BI-1744-CL, LAS-100977, and PF-00610355) are currently under development with the hopes of achieving once-daily dosing. Lanthanum 187-190 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 30-35 19816179-2 2010 RECENT FINDINGS: A variety of beta2-agonists with long half-lives, also called ultra long-acting beta2-agonists (ultra-LABAs; indacaterol, carmoterol, milveterol, GSK-642444, BI-1744-CL, LAS-100977, and PF-00610355) are currently under development with the hopes of achieving once-daily dosing. Lanthanum 187-190 potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens 97-102 19277862-0 2009 Enhancement of lanthanum (III) on sodium currents in acutely isolated hippocampal CA1 neurons of rat. Lanthanum 15-24 carbonic anhydrase 1 Rattus norvegicus 82-85 19362545-6 2009 Increasing STIM1 expression resulted in enhanced Ca(2+) influx after store depletion and subsequent Ca(2+) add-back; the influx was inhibited when the oocytes were pretreated with lanthanum, a specific inhibitor of store-operated Ca(2+) channels. Lanthanum 180-189 stromal interaction molecule 1 Homo sapiens 11-16 19555690-0 2009 Lanthanum ions inhibit the mammalian Sec61 complex in its channel dynamics and protein transport activity. Lanthanum 0-9 SEC61 translocon subunit alpha 1 Homo sapiens 37-42 19555690-2 2009 Millimolar concentrations of lanthanum ions simultaneously restricted the dynamics of the Sec61 channel and inhibited translocation of polypeptides. Lanthanum 29-38 SEC61 translocon subunit alpha 1 Homo sapiens 90-95 19555690-3 2009 Molecular modeling indicates that lanthanum binding sites cluster at the putative lateral gate of the Sec61 complex and suggests that structural flexibility of the lateral gate is essential for channel and protein transport activities of the Sec61 complex. Lanthanum 34-43 SEC61 translocon subunit alpha 1 Homo sapiens 102-107 19555690-3 2009 Molecular modeling indicates that lanthanum binding sites cluster at the putative lateral gate of the Sec61 complex and suggests that structural flexibility of the lateral gate is essential for channel and protein transport activities of the Sec61 complex. Lanthanum 34-43 SEC61 translocon subunit alpha 1 Homo sapiens 242-247 19374367-0 2009 Three lanthanum MOF polymorphs: insights into kinetically and thermodynamically controlled phases. Lanthanum 6-15 lysine acetyltransferase 8 Homo sapiens 16-19 19157964-5 2009 The second harmonic generation (SHG) from the material was confirmed using Nd:YAG laser which shows that LAS has 23% SHG efficiency of that of the standard KDP. Lanthanum 105-108 WNK lysine deficient protein kinase 1 Homo sapiens 156-159 19548582-0 2009 [Effects of lanthanum on memory and expression of c-fos mRNA and c-Fos protein of cerebral cortex in rats]. Lanthanum 12-21 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 50-55 19548582-0 2009 [Effects of lanthanum on memory and expression of c-fos mRNA and c-Fos protein of cerebral cortex in rats]. Lanthanum 12-21 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 65-70 19548582-7 2009 The expression levels of c-fos mRNA and c-Fos protein in cerebral cortex of low dose lanthanum group were lower significantly than control values. Lanthanum 85-94 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 25-30 19548582-7 2009 The expression levels of c-fos mRNA and c-Fos protein in cerebral cortex of low dose lanthanum group were lower significantly than control values. Lanthanum 85-94 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 40-45 19548582-8 2009 As to middle dose lanthanum group, the expression levels of c-fos mRNA in cerebral cortex were lower significantly than control values, and c-Fos protein expression were lower significantly than control and low dose lanthanum group. Lanthanum 18-27 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 60-65 19548582-9 2009 Both c-fos mRNA and c-Fos protein expression in cerebral cortex of high dose lanthanum group decreased significantly as compared with control and low dose lanthanum group. Lanthanum 77-86 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 5-10 19548582-9 2009 Both c-fos mRNA and c-Fos protein expression in cerebral cortex of high dose lanthanum group decreased significantly as compared with control and low dose lanthanum group. Lanthanum 77-86 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 20-25 19548582-9 2009 Both c-fos mRNA and c-Fos protein expression in cerebral cortex of high dose lanthanum group decreased significantly as compared with control and low dose lanthanum group. Lanthanum 155-164 Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus 5-10 18979059-3 2009 We examined the effects of lanthanum in Jurkat cells and human peripheral lymphocytes (HPL), and we found that it was cytotoxic and genotoxic on both cell lines. Lanthanum 27-36 galectin 1 Homo sapiens 87-90 21582071-0 2009 Hexa-mu-chlorido-hexa-chlorido(eta-hexa-methyl-benzene)trialuminium(III)lanthanum(III) benzene solvate. Lanthanum 72-81 hexosaminidase subunit alpha Homo sapiens 0-4 21582071-0 2009 Hexa-mu-chlorido-hexa-chlorido(eta-hexa-methyl-benzene)trialuminium(III)lanthanum(III) benzene solvate. Lanthanum 72-81 hexosaminidase subunit alpha Homo sapiens 17-21 21582071-0 2009 Hexa-mu-chlorido-hexa-chlorido(eta-hexa-methyl-benzene)trialuminium(III)lanthanum(III) benzene solvate. Lanthanum 72-81 endothelin receptor type A Homo sapiens 31-34 21582071-0 2009 Hexa-mu-chlorido-hexa-chlorido(eta-hexa-methyl-benzene)trialuminium(III)lanthanum(III) benzene solvate. Lanthanum 72-81 hexosaminidase subunit alpha Homo sapiens 35-39 21582071-2 2009 Three chloridoaluminate groups and a hexa-methyl-benzene mol-ecule are bound to the central lanthanum(III) ion, forming a distorted penta-gonal bipyramid with the eta(6)-coordinated arene located at the apical position. Lanthanum 92-101 hexosaminidase subunit alpha Homo sapiens 37-41 21582071-2 2009 Three chloridoaluminate groups and a hexa-methyl-benzene mol-ecule are bound to the central lanthanum(III) ion, forming a distorted penta-gonal bipyramid with the eta(6)-coordinated arene located at the apical position. Lanthanum 92-101 endothelin receptor type A Homo sapiens 163-166 17606467-8 2007 This hypothesis is supported by the fact that dNKAIN, but not NKAIN1, induces voltage-independent amiloride-insensitive Na(+)-specific conductance that can be blocked by lanthanum. Lanthanum 170-179 Na,K-ATPase Interacting Drosophila melanogaster 46-52 18810761-0 2008 Lanthanum enhances in vitro osteoblast differentiation via pertussis toxin-sensitive gi protein and ERK signaling pathway. Lanthanum 0-9 mitogen-activated protein kinase 1 Homo sapiens 100-103 18661197-3 2008 Lanthanum and gadolinium ions, potential blockers of mechanosensitive calcium ion-permeable channels (mechanoreceptors), nullified reorientation of microtubules as well as up-regulation of expression of VaTUG and VaGCP3 by hypergravity. Lanthanum 0-9 tubulin gamma-1 chain Vigna angularis 203-208 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 11-14 MIR164a Arabidopsis thaliana 42-48 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 11-14 MIR164a Arabidopsis thaliana 97-103 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 11-14 MIR164a Arabidopsis thaliana 162-168 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 11-14 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Arabidopsis thaliana 189-193 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 11-14 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Arabidopsis thaliana 198-202 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 227-230 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Arabidopsis thaliana 68-72 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 227-230 MIR164a Arabidopsis thaliana 97-103 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 227-230 MIR164a Arabidopsis thaliana 162-168 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 227-230 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Arabidopsis thaliana 189-193 18346190-9 2008 Studies on LAS transcript accumulation in mir164 triple mutants and cuc3-2 plants overexpressing miR164 suggest that regulation of axillary meristem formation by miR164 is mediated through CUC1 and CUC2, which in turn regulate LAS. Lanthanum 227-230 NAC (No Apical Meristem) domain transcriptional regulator superfamily protein Arabidopsis thaliana 198-202 17649886-0 2007 [Effects of lanthanum on inhibition of lipopolysaccharide induced NF-kappaB activation]. Lanthanum 12-21 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 66-75 17596195-7 2007 In addition to a previously described block by ruthenium red, we identified the trivalent cations, lanthanum (La(3+)) and gadolinium (Gd(3+)) as potent blockers of TRPV2. Lanthanum 99-108 transient receptor potential cation channel, subfamily V, member 2 Rattus norvegicus 164-169 17449629-3 2007 The effect of the las quorum-sensing system was dependent on the rhl quorum-sensing system in regulating denitrification. Lanthanum 18-21 ATP-dependent RNA helicase RhlB Pseudomonas aeruginosa PAO1 65-68 17649886-15 2007 Lanthanum can inhibit lipopolysaccharide induced NF-kappaB activation. Lanthanum 0-9 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 49-58 17209595-3 2007 Unusually for ionic surfactants, the difference in compositions between the coexisting L1 and Lalpha phases is large (L1 = approximately 20 wt % LAS; Lalpha = approximately 65 wt %). Lanthanum 145-148 immunoglobulin kappa variable 1-16 Homo sapiens 87-100 17201399-1 2007 The motion of a single lanthanum atom inside a C82 (C2v) fullerene cage has been investigated by means of the hybrid density functional method (B3LYP). Lanthanum 23-32 complement C8 beta chain Homo sapiens 47-50 17075922-8 2007 PTX-induced intracellular acidification was completely prevented by several inhibitors of the plasma membrane calcium ATPase (PMCA), including orthovanadate, lanthanum, high extracellular pH, and caloxin 2A1. Lanthanum 158-167 ATPase plasma membrane Ca2+ transporting 2 Homo sapiens 94-124 17075922-8 2007 PTX-induced intracellular acidification was completely prevented by several inhibitors of the plasma membrane calcium ATPase (PMCA), including orthovanadate, lanthanum, high extracellular pH, and caloxin 2A1. Lanthanum 158-167 ATPase plasma membrane Ca2+ transporting 2 Homo sapiens 126-130 17194921-0 2006 Effect of lanthanum ions (La3+) on ferritin-regulated antioxidant process under PEG stress. Lanthanum 10-19 Fer2 Triticum aestivum 35-43 17194921-1 2006 The physiological effects of lanthanum(III) ions on the ferritin-regulated antioxidant process were studied in wheat (Triticum aestivum L.) seedlings under polyethylene glycol (PEG) stress. Lanthanum 29-38 Fer2 Triticum aestivum 56-64 16765919-7 2006 The protective effect of TRPC1 was blocked by the addition of TRPC1 blockers lanthanum, or 2APB. Lanthanum 77-86 transient receptor potential cation channel subfamily C member 1 Homo sapiens 25-30 16765919-7 2006 The protective effect of TRPC1 was blocked by the addition of TRPC1 blockers lanthanum, or 2APB. Lanthanum 77-86 transient receptor potential cation channel subfamily C member 1 Homo sapiens 62-67 16474884-1 2006 Exposure of the dinuclear hydroxo complex {[La(tpen)(mu-OH)]2(mu-eta1:eta1OTf)}OTf3 to air results in the immediate uptake of atmospheric CO2 affording an unusual hexanuclear lanthanum carbonato complex in which the carbonate anions are ligated in a mu3-eta1:eta1:eta2 and mu3-eta1:eta2:eta2 fashion. Lanthanum 175-184 secreted phosphoprotein 1 Homo sapiens 70-74 16502327-0 2006 Lanthanum induces extracellular signal-regulated kinase phosphorylation through different mechanisms in HeLa cells and NIH 3T3 cells. Lanthanum 0-9 mitogen-activated protein kinase 1 Homo sapiens 18-55 16518694-9 2006 The latter were determined from chemical shift differences between assigned signals in thulium(III) and lanthanum(III) derivatives of Calbindin D 9K and they were interpreted on the basis of a structural model for the lanthanide-substituted protein. Lanthanum 104-113 S100 calcium binding protein G Homo sapiens 134-148 15961724-6 2005 By employing GF-109203X (protein kinase C [PKC] inhibitor) and lanthanum (La3+), a nonselective cation channel blocker, we observed that SDHG evoked ASM contractile response via PKC-dependent and PKC-independent (but Ca2+-dependent) pathways. Lanthanum 63-72 Prkca Cavia porcellus 178-181 16474884-1 2006 Exposure of the dinuclear hydroxo complex {[La(tpen)(mu-OH)]2(mu-eta1:eta1OTf)}OTf3 to air results in the immediate uptake of atmospheric CO2 affording an unusual hexanuclear lanthanum carbonato complex in which the carbonate anions are ligated in a mu3-eta1:eta1:eta2 and mu3-eta1:eta2:eta2 fashion. Lanthanum 175-184 secreted phosphoprotein 1 Homo sapiens 70-74 16474884-1 2006 Exposure of the dinuclear hydroxo complex {[La(tpen)(mu-OH)]2(mu-eta1:eta1OTf)}OTf3 to air results in the immediate uptake of atmospheric CO2 affording an unusual hexanuclear lanthanum carbonato complex in which the carbonate anions are ligated in a mu3-eta1:eta1:eta2 and mu3-eta1:eta2:eta2 fashion. Lanthanum 175-184 secreted phosphoprotein 1 Homo sapiens 70-74 16375389-0 2005 Destructive adsorption of CCl4 over lanthanum-based solids: linking activity to acid-base properties. Lanthanum 36-45 C-C motif chemokine ligand 4 Homo sapiens 26-30 16471057-3 2005 With the larger lanthanum(III) ion only a well defined 1 : 1 complex (X-ray structure: [LLa(NO3)(MeOH)2]2(NO3)2) can be observed but probably 2 : 1 complexes are also formed. Lanthanum 16-25 NBL1, DAN family BMP antagonist Homo sapiens 92-95 16471057-3 2005 With the larger lanthanum(III) ion only a well defined 1 : 1 complex (X-ray structure: [LLa(NO3)(MeOH)2]2(NO3)2) can be observed but probably 2 : 1 complexes are also formed. Lanthanum 16-25 NBL1, DAN family BMP antagonist Homo sapiens 106-109 16671565-0 2005 Lanthanum potentiates GABA-activated currents in rat pyramidal neurons of CA1 hippocampal field. Lanthanum 0-9 carbonic anhydrase 1 Rattus norvegicus 74-77 16671565-1 2005 In CA1 hippocampal pyramidal neurons, lanthanum ions increased the amplitude of GABA-activated currents and shifted the dose-dependence curve to the left, which attests to increased affinity of GABAA-receptors to GABA. Lanthanum 38-47 carbonic anhydrase 1 Rattus norvegicus 3-6 15961724-6 2005 By employing GF-109203X (protein kinase C [PKC] inhibitor) and lanthanum (La3+), a nonselective cation channel blocker, we observed that SDHG evoked ASM contractile response via PKC-dependent and PKC-independent (but Ca2+-dependent) pathways. Lanthanum 63-72 Prkca Cavia porcellus 178-181 16285901-0 2004 Lanthanum inhibited the binding of LPS with monocyte and CD 14 expression upregulation. Lanthanum 0-9 CD14 molecule Homo sapiens 57-62 18970155-8 2005 Using a 200mgL(-1) lanthanum solution as a chemical modifier, the average relative standard deviations of 7 and 16% (at 3-15mugL(-1) level) and characteristic concentrations of 0.47 and 0.77mugL(-1) for naphtha and petroleum condensates, respectively, were observed. Lanthanum 19-28 LLGL scribble cell polarity complex component 1 Homo sapiens 11-17 15542611-7 2005 Protection of SH-SY5Y cells against MPP(+) was significantly decreased upon the overexpression of antisense TRPC1 cDNA construct or the addition of a nonspecific transient receptor potential channel blocker lanthanum. Lanthanum 207-216 transient receptor potential cation channel subfamily C member 1 Homo sapiens 108-113 15247375-9 2004 Application of the calcium channel blocker lanthanum reduced the height of the first Ca2+ peak and concomitantly inhibited GST1 expression. Lanthanum 43-52 glutathione S-transferase 6 Arabidopsis thaliana 123-127 15342096-0 2004 Layer-specific potentiation of evoked IPSCs in rat hippocampal CA1 pyramidal cells by lanthanum. Lanthanum 86-95 carbonic anhydrase 1 Rattus norvegicus 63-66 15144810-1 2004 We studied the direct micropatterning of a lanthanum-based thin film on a template of self-assembled monolayers in an aqueous solution at 80 degrees C. The template composed of silanol and octadecyl areas was prepared by UV-modified octadecyltrichlorosilane SAMs through a photomask. Lanthanum 43-52 methionine adenosyltransferase 1A Homo sapiens 258-262 12832510-8 2003 The tip-link antigen is lanthanum sensitive and, like tip links, reappears on the surface of the hair bundle after calcium chelation. Lanthanum 24-33 TOR signaling pathway regulator Homo sapiens 4-7 15044722-7 2004 As the same arrangement of active-site residues is also found in the N-terminal, cryptic peptidase domain of sonic hedgehog, we propose that this arrangement of active-site residues be called the "LAS" arrangement, because it is present in lysostaphin-type enzymes, D-Ala-D-Ala metallopeptidases, and in the cryptic peptidase in the N-domain of sonic hedgehog. Lanthanum 197-200 sonic hedgehog signaling molecule Homo sapiens 109-123 15044722-7 2004 As the same arrangement of active-site residues is also found in the N-terminal, cryptic peptidase domain of sonic hedgehog, we propose that this arrangement of active-site residues be called the "LAS" arrangement, because it is present in lysostaphin-type enzymes, D-Ala-D-Ala metallopeptidases, and in the cryptic peptidase in the N-domain of sonic hedgehog. Lanthanum 197-200 sonic hedgehog signaling molecule Homo sapiens 345-359 14500500-2 2003 Las and Rhl are two major quorum-sensing components, and they are regulated by their corresponding autoinducers, N-3-oxododecanoyl homoserine lactone (3-oxo-C(12)-HSL) and N-butyryl-L-homoserine lactone (C(4)-HSL). Lanthanum 0-3 lipase E, hormone sensitive type Homo sapiens 163-166 14500500-2 2003 Las and Rhl are two major quorum-sensing components, and they are regulated by their corresponding autoinducers, N-3-oxododecanoyl homoserine lactone (3-oxo-C(12)-HSL) and N-butyryl-L-homoserine lactone (C(4)-HSL). Lanthanum 0-3 lipase E, hormone sensitive type Homo sapiens 209-212 14534033-6 2003 The peak [Ca2+]i due to KCl application was reduced in the presence of lead (60%), cobalt (35%), zinc (62%), cadmium (71%), thallium (27%), and lanthanum (66%). Lanthanum 144-153 carbonic anhydrase 2 Mus musculus 10-13 12770646-7 2003 Mitochondrial uncouplers increased FAS expression significantly while [Ca(2+)]i antagonism with lanthanum decreased FAS expression (P <0.001). Lanthanum 96-105 fatty acid synthase Mus musculus 116-119 12451594-8 2003 Furthermore, lanthanum/zinc treatment also facilitated the early onset of actin-based vaccinia motility, a process that also utilizes Arp2/3 and N-WASP for nucleation and the zyxin-VASP-profilin complex for efficient elongation. Lanthanum 13-22 actin related protein 2 Homo sapiens 134-138 12839336-10 2003 Absence of a functional iNOS gene in iNOSKO mice resulted in a significant reduction of apical diffusion of lanthanum after DNBS-induced colitis. Lanthanum 108-117 nitric oxide synthase 2, inducible Mus musculus 24-28 12451594-8 2003 Furthermore, lanthanum/zinc treatment also facilitated the early onset of actin-based vaccinia motility, a process that also utilizes Arp2/3 and N-WASP for nucleation and the zyxin-VASP-profilin complex for efficient elongation. Lanthanum 13-22 WASP like actin nucleation promoting factor Homo sapiens 145-151 12451594-8 2003 Furthermore, lanthanum/zinc treatment also facilitated the early onset of actin-based vaccinia motility, a process that also utilizes Arp2/3 and N-WASP for nucleation and the zyxin-VASP-profilin complex for efficient elongation. Lanthanum 13-22 vasodilator stimulated phosphoprotein Homo sapiens 181-185 12388058-9 2002 Application of calmidazolium to cells expressing TRPC4 beta led to a significant increase in the inward current of these cells at both the whole cell and single-channel level, and currents were sensitive to block by 10 microM lanthanum, niflumic acid, and DIDS. Lanthanum 226-235 transient receptor potential cation channel, subfamily C, member 4 Mus musculus 49-54 12563244-12 2003 In rats treated with TNF-alpha the total serum bile acid concentration increased and lanthanum temporarily accumulated in BC. Lanthanum 85-94 tumor necrosis factor Rattus norvegicus 21-30 12147347-3 2002 Loop III of calmodulin with two Gly linkers in CD2 (CaM-CD2-III-5G) has metal affinities with K(d) values of 1.86 x 10(-4) and 5.8 x 10(-5) M for calcium and lanthanum, respectively. Lanthanum 158-167 CD2 molecule Homo sapiens 47-50 12383867-5 2002 Removal of extracellular calcium eliminated CCK-induced [Ca(2+)](i) increments, as did the addition of the calcium channel inhibitors nickel (1mM) and lanthanum (5mM). Lanthanum 151-160 cholecystokinin Cavia porcellus 44-47 12147347-3 2002 Loop III of calmodulin with two Gly linkers in CD2 (CaM-CD2-III-5G) has metal affinities with K(d) values of 1.86 x 10(-4) and 5.8 x 10(-5) M for calcium and lanthanum, respectively. Lanthanum 158-167 CD2 molecule Homo sapiens 52-66 11867697-6 2002 TaMDR1 was significantly induced by the exposure to lanthanum, gadolinium and ruthenium red, which are known as inhibitors of calcium channels. Lanthanum 52-61 ABC transporter B family member 4 Triticum aestivum 0-6 12393933-9 2002 Absence of a functional IL-10 gene in IL-10KO mice resulted in a significant augmentation of apical diffusion of lanthanum after DNBS-induced colitis. Lanthanum 113-122 interleukin 10 Mus musculus 24-29 11704678-8 2002 Lanthanum, a trivalent ion that acts as an agonist of ABA signaling, potentiated ABI5 transactivation. Lanthanum 0-9 Basic-leucine zipper (bZIP) transcription factor family protein Arabidopsis thaliana 81-85 12373543-0 2002 Repeated topical application of growth hormone attenuates blood-spinal cord barrier permeability and edema formation following spinal cord injury: an experimental study in the rat using Evans blue, ([125])I-sodium and lanthanum tracers. Lanthanum 218-227 gonadotropin releasing hormone receptor Rattus norvegicus 32-46 11514591-5 2001 CapG-null macrophages also demonstrate approximately 50% impairment of immunoglobulin G, and complement-opsonized phagocytosis and lanthanum-induced vesicle rocketing. Lanthanum 131-140 capping protein (actin filament), gelsolin-like Mus musculus 0-4 11325870-9 2001 Ang II no longer elicited a [Ca(2+)](i) increase in the presence of lanthanum (25 micromol/L). Lanthanum 68-77 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 0-6 11423385-5 2001 The inhibitory effect of carbachol on the AVP action was almost completely abolished by the cholinergic antagonists atropine, pirenzepine, 4-diphenylacetoxy-N-methylpiperidine methiodide (4-DAMP) and the calcium antagonist lanthanum. Lanthanum 223-232 arginine vasopressin Homo sapiens 42-45 11139577-0 2001 Functional interactions of lanthanum and phospholipase D with the abscisic acid signaling effectors VP1 and ABI1-1 in rice protoplasts. Lanthanum 27-36 regulatory protein viviparous-1 Zea mays 100-103 11101305-7 2000 Analysis of the phosphoenzyme intermediate formed in the presence of lanthanum showed that the phosphorylation reaction was not affected, but the maximum amount of phosphoenzyme was reduced to the same extent as the Ca(2+) transport activity. Lanthanum 69-78 carbonic anhydrase 2 Cricetulus griseus 216-222 10710533-7 2000 The reductions in phospholipid, SP-B, and SP-C in LA fractions measured during PCP were associated with an increase in the minimum surface tension of LAs as measured by pulsating bubble surfactometer (13.1 +/- 1.1 vs. 5.4 +/- 1.8 mN/m; P < 0.05). Lanthanum 150-153 surfactant associated protein B Mus musculus 32-36 11198854-7 2000 The data analysis of EXAFS and LAXS measurements assuming eight-coordination around lanthanum yielded an La-O bond distance of 2.50(2) A, and an La...S distance of 3.70(3) A, giving an La-O-S angle of 133(2) degrees. Lanthanum 84-93 interleukin 4 induced 1 Homo sapiens 105-109 11198854-7 2000 The data analysis of EXAFS and LAXS measurements assuming eight-coordination around lanthanum yielded an La-O bond distance of 2.50(2) A, and an La...S distance of 3.70(3) A, giving an La-O-S angle of 133(2) degrees. Lanthanum 84-93 interleukin 4 induced 1 Homo sapiens 185-189 11198854-9 2000 The La-O bond distance is consistent with seven-coordination around lanthanum, on the basis of the variation of the ionic radii of the lanthanum(III) ion with different coordination numbers. Lanthanum 68-77 interleukin 4 induced 1 Homo sapiens 4-8 11198854-9 2000 The La-O bond distance is consistent with seven-coordination around lanthanum, on the basis of the variation of the ionic radii of the lanthanum(III) ion with different coordination numbers. Lanthanum 135-144 interleukin 4 induced 1 Homo sapiens 4-8 10898527-0 2000 Altered gating of HERG potassium channels by cobalt and lanthanum. Lanthanum 56-65 potassium voltage-gated channel subfamily H member 2 Homo sapiens 18-22 10710533-7 2000 The reductions in phospholipid, SP-B, and SP-C in LA fractions measured during PCP were associated with an increase in the minimum surface tension of LAs as measured by pulsating bubble surfactometer (13.1 +/- 1.1 vs. 5.4 +/- 1.8 mN/m; P < 0.05). Lanthanum 150-153 sparse coat Mus musculus 42-46 10404770-4 1999 We recently raised a series of murine monoclonal antibodies against human Beta-2-glycoprotein I (beta2GPI) with LA activity similar to affinity purified human beta2GPI-dependent LAs. Lanthanum 178-181 apolipoprotein H Homo sapiens 159-167 11144685-5 2000 LAs have been found to be directed towards either prothrombin or beta 2GPI bound to anionic phospholipids. Lanthanum 0-3 apolipoprotein H Homo sapiens 65-74 9213226-7 1997 Lanthanum (La3+) depresses IGFBP release from all three cell types (> 80% for GM10 and T98G cells and > 65% for MDBK cells). Lanthanum 0-9 insulin like growth factor binding protein 2 Homo sapiens 27-32 9927628-2 1999 Several LAs induce subtle changes in the vibrational spectrum of the nAChR over a range of concentrations consistent with their reported nAChR-binding affinities. Lanthanum 8-11 cholinergic receptor nicotinic alpha 4 subunit Homo sapiens 69-74 9927628-2 1999 Several LAs induce subtle changes in the vibrational spectrum of the nAChR over a range of concentrations consistent with their reported nAChR-binding affinities. Lanthanum 8-11 cholinergic receptor nicotinic alpha 4 subunit Homo sapiens 137-142 9927628-6 1999 Our results suggest that LAs stabilize multiple conformations of the nAChR by binding to at least two conformationally sensitive LA-binding sites. Lanthanum 25-28 cholinergic receptor nicotinic alpha 4 subunit Homo sapiens 69-74 9073491-6 1997 Lanthanum and verapamil (10(-4) M) markedly inhibited Vg synthesis, while diltiazem (10(-4) M) was insignificant. Lanthanum 0-9 LOC100136735 Oncorhynchus mykiss 54-56 9138723-1 1997 The effect of the trivalent cation lanthanum (La3+) on voltage-dependent gating of a cloned mammalian neuronal Kv1.1 potassium channel was studied under whole-cell voltage-clamp conditions in oocytes of Xenopus laevis. Lanthanum 35-44 potassium voltage-gated channel subfamily A member 1 Homo sapiens 111-116 8834339-5 1996 The effect of an SP antagonist, of Ca2+ channel block with verapamil, and of the calcium analogue lanthanum on the SP response were also tested. Lanthanum 98-107 tachykinin precursor 1 Homo sapiens 115-117 8952695-4 1996 The prompt AII-induced [Ca2+]i spike was not affected by incubating HCEC in Ca(2+)-free medium containing 2 mM EGTA or by pretreating the cultures with the Ca2+ channel blockers, methoxyverapamil (D600; 50 microM), nickel (1 mM), or lanthanum (1 mM), suggesting that the activation of AII receptors on HCEC triggers the release of Ca2+ from intracellular stores. Lanthanum 233-242 angiotensinogen Homo sapiens 11-14 8661960-9 1996 The lanthanum incubation method indirectly detects the matrix Ca-binding components (which bind La ions), and the calcification initiation sites (which precipitate a LaP-mineral phase). Lanthanum 4-13 acid phosphatase 2, lysosomal Rattus norvegicus 166-169 8638662-6 1996 the sustained depolarization induced by BK was prevented by incubating the cells with the calcium channel blocker lanthanum. Lanthanum 114-123 kininogen 1 Bos taurus 40-42 8721751-2 1996 In Arabidopsis, lanthanum or EGTA caused a partial inhibition of both cold shock [Ca2+]cyt elevation and cold-dependent kin1 gene expression. Lanthanum 16-25 stress-responsive protein (KIN1) / stress-induced protein (KIN1) Arabidopsis thaliana 120-124 8834339-12 1996 However, compared to SP alone, the combination of SP and phosphoramidon induced a novel delayed lanthanum-sensitive rise in CBF. Lanthanum 96-105 tachykinin precursor 1 Homo sapiens 21-23 8834339-12 1996 However, compared to SP alone, the combination of SP and phosphoramidon induced a novel delayed lanthanum-sensitive rise in CBF. Lanthanum 96-105 tachykinin precursor 1 Homo sapiens 50-52 15091518-7 1995 Comparable affinity of culture MM1 for both methane and C(11)LAS ( [Formula: see text], respectively), and more than four times higher maximum transformation rate for methane than for C(11)LAS ( [Formula: see text] (dry weight) cells day(-1), respectively), were determined. Lanthanum 60-64 prefoldin subunit 5 Homo sapiens 31-34 9223015-12 1995 The significantly higher affinity of lanthanide ions than Ca2+ for the peptides could well play a role in the inhibitory activity of lanthanum on the signal transduction of the CCK family of hormones. Lanthanum 133-142 cholecystokinin Homo sapiens 177-180 7554102-4 1995 The efflux as well as an exchange of external Ca2+ with internal 45Ca2+ was inhibited by lanthanum. Lanthanum 89-98 carbonic anhydrase 2 Homo sapiens 46-49 15091518-7 1995 Comparable affinity of culture MM1 for both methane and C(11)LAS ( [Formula: see text], respectively), and more than four times higher maximum transformation rate for methane than for C(11)LAS ( [Formula: see text] (dry weight) cells day(-1), respectively), were determined. Lanthanum 61-64 prefoldin subunit 5 Homo sapiens 31-34 10055197-0 1993 Electronic structure of metallofullerene LaC82: Electron transfer from lanthanum to C82. Lanthanum 71-80 complement C8 beta chain Homo sapiens 43-46 7925655-4 1994 MDCK cells expressed both ZO-1 and 7H6 antigen at tight junctions, which maintain a tight barrier as determined by resistance to lanthanum permeation and high transepithelial electrical resistance (TER, 1500 ohm-cm2). Lanthanum 129-138 tight junction protein 1 Canis lupus familiaris 26-38 7508206-3 1994 With a bath Ca2+ concentration ([Ca2+]) of 1 mM, 10 nM SP elicited an increase in cytosolic [Ca2+] ([Ca2+]i) from a baseline of 25 +/- 4 nM to a peak of 808 +/- 120 nM, followed by a slowly declining plateau phase, which was absent in Ca(2+)-free bath and was abolished by addition of extracellular lanthanum or nickel. Lanthanum 299-308 tachykinin precursor 1 Homo sapiens 55-57 7549541-9 1994 Furthermore, under low pH conditions, where the LAs are in a reversibly denatured, molten globule form, the spectra are more similar, species variation is minimal and the spectral differences from lysozyme are in fact smaller. Lanthanum 48-51 lysozyme Homo sapiens 197-205 8138106-4 1993 Ultrathin sections of lanthanum-infiltrated samples were observed by transmission electron microscopy at various points during follicular development and hormone-induced maturation: vitellogenic oocytes (< 350 microns), full-grown oocytes (350-400 microns), hCG-stimulated (maturationally competent) oocytes, hCG/MIS-stimulated (early-maturation, hydrating) oocytes, and ovulated oocytes. Lanthanum 22-31 hypertrichosis 2 (generalised, congenital) Homo sapiens 261-264 8138106-4 1993 Ultrathin sections of lanthanum-infiltrated samples were observed by transmission electron microscopy at various points during follicular development and hormone-induced maturation: vitellogenic oocytes (< 350 microns), full-grown oocytes (350-400 microns), hCG-stimulated (maturationally competent) oocytes, hCG/MIS-stimulated (early-maturation, hydrating) oocytes, and ovulated oocytes. Lanthanum 22-31 hypertrichosis 2 (generalised, congenital) Homo sapiens 312-315 8138106-4 1993 Ultrathin sections of lanthanum-infiltrated samples were observed by transmission electron microscopy at various points during follicular development and hormone-induced maturation: vitellogenic oocytes (< 350 microns), full-grown oocytes (350-400 microns), hCG-stimulated (maturationally competent) oocytes, hCG/MIS-stimulated (early-maturation, hydrating) oocytes, and ovulated oocytes. Lanthanum 22-31 anti-Mullerian hormone Homo sapiens 316-319 8407359-4 1993 Lanthanum tracer studies indicated that some of these SOD-positive structures might be tubulovesicles continuous with the extracellular space. Lanthanum 0-9 superoxide dismutase 1 Homo sapiens 54-57 8437103-4 1993 In contrast, the calcium-chelator, EGTA, and lanthanum, an inorganic compound that blocks voltage-sensitive calcium channels and Na(+)-Ca++ exchanger activity, enhanced anoxia-induced D-[3H]aspartate release. Lanthanum 45-54 nascent polypeptide associated complex subunit alpha Homo sapiens 129-137 9908938-0 1993 Spin-polarizing 3He nuclei with an arc-lamp-pumped neodymium-doped lanthanum magnesium hexaluminate laser. Lanthanum 67-76 spindlin 1 Homo sapiens 0-4 1293036-4 1992 Use of lanthanum (a calcium antagonist) in place of calcium in the medium used resulted in a significant decrease in the levels of hCG in the medium. Lanthanum 7-16 hypertrichosis 2 (generalised, congenital) Homo sapiens 131-134 1385450-4 1992 The binding of mAbL1 (2E12) to the neurons expressing L1 molecule induced an inward current inhibited by calcium channel blockers such as nifedipine and Lanthanum. Lanthanum 153-162 c-abl oncogene 1, non-receptor tyrosine kinase Mus musculus 15-20 1279483-1 1992 The effect of lanthanum ion (La3+) on gamma-aminobutyric acid (GABA)-mediated Cl- currents was examined in the alpha 1 beta 2 or alpha 1 beta 2 gamma 2 subtype of GABAA receptors expressed in a human kidney cell line (A293), using a whole-cell configuration of patch-clamp techniques. Lanthanum 14-23 adrenoceptor alpha 1D Homo sapiens 111-118 1279483-1 1992 The effect of lanthanum ion (La3+) on gamma-aminobutyric acid (GABA)-mediated Cl- currents was examined in the alpha 1 beta 2 or alpha 1 beta 2 gamma 2 subtype of GABAA receptors expressed in a human kidney cell line (A293), using a whole-cell configuration of patch-clamp techniques. Lanthanum 14-23 adrenoceptor alpha 1D Homo sapiens 129-151 1335501-2 1992 The effects of the extracellular divalent cations barium, calcium, cadmium, cobalt, magnesium, manganese, nickel and zinc and the trivalent cation lanthanum on macroscopic sodium current (INa) were characterized in enzymatically isolated single canine cardiac Purkinje cells under voltage clamp at 9-14 degrees C. 2. Lanthanum 147-156 internexin neuronal intermediate filament protein alpha Canis lupus familiaris 188-191 1382374-5 1992 Because of the inhibitory effect of lanthanum or cerium compounds on membrane ATPase and immunological function of epidermal Langerhans cells we propose that these compounds may be used in the treatment of atopic eczema, where both histamine-releasing mast cells and IgE-bearing Langerhans cell play a pathogenetically important role. Lanthanum 36-45 dynein axonemal heavy chain 8 Homo sapiens 78-84 1836927-7 1991 These studies demonstrate that ANF causes accelerated passage of both HRP and ionic lanthanum from blood into choroid plexuses with passage of ionic lanthanum into the ventricular cavity through the apical tight junctions of choroidal epithelial cells. Lanthanum 84-93 natriuretic peptide A Rattus norvegicus 31-34 1620579-5 1992 It is concluded that in cells expressing the ras oncogene, bradykinin activates lanthanum sensitive calcium entry from the extracellular space. Lanthanum 80-89 kininogen 1 Homo sapiens 59-69 1836927-7 1991 These studies demonstrate that ANF causes accelerated passage of both HRP and ionic lanthanum from blood into choroid plexuses with passage of ionic lanthanum into the ventricular cavity through the apical tight junctions of choroidal epithelial cells. Lanthanum 149-158 natriuretic peptide A Rattus norvegicus 31-34 1838262-2 1991 Sorted CD8+CD11b- cells from 3 of the patients with non-resectable carcinoma and from 1 of the patients with resectable carcinoma showed LAS cell activity. Lanthanum 137-140 CD8a molecule Homo sapiens 7-10 1838262-2 1991 Sorted CD8+CD11b- cells from 3 of the patients with non-resectable carcinoma and from 1 of the patients with resectable carcinoma showed LAS cell activity. Lanthanum 137-140 integrin subunit alpha M Homo sapiens 11-16 2091659-3 1990 We report a patient with panhypogammaglobulinemia who developed anaphylactoid reactions to two different LAs (lignocaine and procaine), associated with positive intradermal skin tests to these agents as well as prilocaine, despite absent detectable IgE in the serum and a negative RAST test to procaine. Lanthanum 105-108 immunoglobulin heavy constant epsilon Homo sapiens 249-252 2280902-3 1990 Alkaline metals, barium (Ba2+), strontium (Sr2+) and other metal cations, manganese (Mn2+) or lanthanum (La3+), support BK-induced [3H]noradrenaline ([3H]NA) release. Lanthanum 94-103 kininogen 1 Homo sapiens 120-122 34500933-1 2021 In this work, lanthanum and manganese co-substitution effects on different properties of bismuth ferrite solid solutions Bi1-xLaxFe0.85Mn0.15O3 (x from 0 to 1) prepared by a sol-gel synthetic approach have been investigated. Lanthanum 14-23 transmembrane BAX inhibitor motif containing 6 Homo sapiens 121-124 2167905-5 1990 INa was not blockable by amiloride (0.1 mmol.l-1), a specific Na-channel blocker in epithelia, but a fully and reversible inhibition was achieved by mucosal application of 1 mmol.l-1 lanthanum (La3+). Lanthanum 183-192 internexin neuronal intermediate filament protein alpha S homeolog Xenopus laevis 0-3 34656894-0 2021 Effect of rare earth element lanthanum on lipid deposition and Wnt10b signaling in the liver of male zebrafish. Lanthanum 29-38 wingless-type MMTV integration site family, member 10b Danio rerio 63-69 34357749-0 2021 Reduction of Amides to Amines with Pinacolborane Catalyzed by Heterogeneous Lanthanum Catalyst La(CH2C6H4NMe2-o)3@SBA-15. Lanthanum 76-85 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 105-109 34357749-2 2021 In this contribution, it was found that the supported lanthanum benzyl material La(CH2C6H4NMe2-o)3@SBA-15 was highly active for the hydroboration of primary, secondary, and tertiary amides to amines with pinacolborane. Lanthanum 54-63 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 90-94 34101455-0 2021 Interactive Effects of Lanthanum and Calcium on Cadmium Accumulation in Wheat with Special Reference to TaNramp5 Expression Regulated by Calmodulin. Lanthanum 23-32 calmodulin 1 Homo sapiens 137-147 35090998-0 2022 Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus. Lanthanum 0-9 VAMP associated protein B and C Rattus norvegicus 20-31 35494628-4 2022 By creating two vacancies for every lanthanum introduced in the structure, the resulting general formula becomes Ag1-3xLax 2xNbO3 (with x <= 0.20 and where is a A-site vacancy), allowing the insertion of lithium ions. Lanthanum 36-45 thioredoxin domain containing 12 Homo sapiens 113-116 35090998-0 2022 Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus. Lanthanum 0-9 B-cell receptor-associated protein 31 Rattus norvegicus 33-38 35090998-0 2022 Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus. Lanthanum 0-9 fission, mitochondrial 1 Rattus norvegicus 39-43 35090998-0 2022 Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus. Lanthanum 0-9 mitofusin 2 Rattus norvegicus 49-53 35090998-0 2022 Lanthanum decreased VAPB-PTPP51, BAP31-FIS1, and MFN2-MFN1 expression of mitochondria-associated membranes and induced abnormal autophagy in rat hippocampus. Lanthanum 0-9 mitofusin 1 Rattus norvegicus 54-58 35160409-2 2022 The complexation properties of PCS and poly (acrylic acid) sodium (PAAS) for lanthanum ions in the solution were compared at the same pH and room temperature. Lanthanum 77-86 PCS Homo sapiens 31-34 35137743-1 2022 N-Oxides can amplify the performance of a lanthanum aminobisphenolate catalyst in the ring-opening polymerization (ROP) of rac-beta-butyrolactone (rac-BBL) to unprecedented levels (TOF/Pm; At RT: 1900 h-1/0.73, At -30 C: 200 h-1/0.82). Lanthanum 42-51 AKT serine/threonine kinase 2 Homo sapiens 123-131 35137743-1 2022 N-Oxides can amplify the performance of a lanthanum aminobisphenolate catalyst in the ring-opening polymerization (ROP) of rac-beta-butyrolactone (rac-BBL) to unprecedented levels (TOF/Pm; At RT: 1900 h-1/0.73, At -30 C: 200 h-1/0.82). Lanthanum 42-51 FEZ family zinc finger 2 Homo sapiens 181-184 2527909-10 1989 A decrease in epidermal Langerhans cell density of 13 to 14% was produced by systemic lanthanum, detected by both ATPase staining and Ia staining, respectively (p less than 0.05). Lanthanum 86-95 dynein, axonemal, heavy chain 8 Mus musculus 114-120 2480158-9 1989 The Cai-activated current, was blocked by external lanthanum and showed a high temperature dependence. Lanthanum 51-60 carbonic anhydrase 1 Homo sapiens 4-7 2562362-3 1989 Anti-p24 were positive in 51 (63.0%) patients at the entry (26/30 symptomless, 13/15 with LAS e 12/23 with ARC) and in 41 (50.6%) at the end of the study (23/27 symptomless, 9/14 with LAS, 7/12 with ARC e 2/28 with AIDS). Lanthanum 90-93 transmembrane p24 trafficking protein 2 Homo sapiens 5-8 2774765-2 1989 Sr2+ induced a concentration-dependent contraction which was reduced by verapamil (5 X 10(-6) and 10(-7) M) and lanthanum (1 and 2 mM). Lanthanum 112-121 Stress response QTL 2 Rattus norvegicus 0-3 3394807-12 1988 In Ca2+-containing conditions, lanthanum ion-reduced AVP evoked [Ca2+]i stimulation to the value observed in Ca2+-free medium. Lanthanum 31-40 arginine vasopressin Rattus norvegicus 53-56 2906299-6 1988 Calcitonin and somatostatin, two agents that inhibit basal and glucose-stimulated insulin secretion, inhibited the insulin response to glucose in presence of LAS infusion. Lanthanum 158-161 insulin Homo sapiens 82-89 2444358-3 1987 Pretreatment with lanthanum (20 microM) abolished the steady level produced by bradykinin but had little effect on the initial, transient rise in cytosolic calcium. Lanthanum 18-27 kininogen 1 Bos taurus 79-89 2967092-11 1988 A second, more sustained component of the Ca2+ transient induced by cholecystokinin was abolished by lanthanum. Lanthanum 101-110 carbonic anhydrase 2 Homo sapiens 42-45 2967092-11 1988 A second, more sustained component of the Ca2+ transient induced by cholecystokinin was abolished by lanthanum. Lanthanum 101-110 cholecystokinin Homo sapiens 68-83 2907451-12 1988 Modification of Ca2+ efflux by lanthanum and barium is suggestive of an exchange of strongly bound extracellular calcium during the slow phase of the efflux from young adult tibial cartilage. Lanthanum 31-40 carbonic anhydrase 2 Rattus norvegicus 16-19 2442157-5 1987 The IGF-II-stimulated calcium influx was dependent on extracellular calcium and was inhibited by lanthanum, cobalt, and tetramethlin but not by nitrendipine. Lanthanum 97-106 insulin-like growth factor 2 Mus musculus 4-10 18964420-0 1987 Hydroxide complexes of lanthanides-VIII Lanthanum(III) in perchlorate medium. Lanthanum 40-49 cytochrome c oxidase subunit 8A Homo sapiens 35-39 3542105-5 1986 Lanthanum blocked the stimulation of renin release by isoprenaline. Lanthanum 0-9 renin Rattus norvegicus 37-42 3031213-7 1987 Lanthanum inhibited both the basal and NGF-stimulated accumulation of [3H]IP, whereas the calcium ionophore A23187, in the absence of NGF, stimulated an accumulation of [3H]IP. Lanthanum 0-9 nerve growth factor Rattus norvegicus 39-42 3545205-4 1987 The IGF-II-mediated increase in [Ca2+]c is totally dependent on extracellular calcium and is blocked by lanthanum. Lanthanum 104-113 insulin-like growth factor 2 Mus musculus 4-10 3006514-5 1986 Pretreatment of the toad bladders with lanthanum (5 X 10(-5) M) also abolished the effect of PTH on vasopressin-stimulated water flow. Lanthanum 39-48 parathyroid hormone Homo sapiens 93-96 3006514-5 1986 Pretreatment of the toad bladders with lanthanum (5 X 10(-5) M) also abolished the effect of PTH on vasopressin-stimulated water flow. Lanthanum 39-48 arginine vasopressin Homo sapiens 100-111 3006514-9 1986 That the effect of PTH was abolished in a low-Ca medium or by pretreatment with lanthanum suggests that cell Ca uptake is required for the effect of PTH on water transport. Lanthanum 80-89 parathyroid hormone Homo sapiens 19-22 3006514-9 1986 That the effect of PTH was abolished in a low-Ca medium or by pretreatment with lanthanum suggests that cell Ca uptake is required for the effect of PTH on water transport. Lanthanum 80-89 parathyroid hormone Homo sapiens 149-152 2867445-6 1985 Furthermore, somatostatin enhanced the uptake of 45calcium in renal cortical slices which could be blocked by lanthanum, an inhibitor of Ca2+ influx. Lanthanum 110-119 somatostatin Rattus norvegicus 13-25 6890383-6 1982 (4) Verapamil, tetracaine and lanthanum inhibited thrombin-induced release of serotonin. Lanthanum 30-39 prothrombin Oryctolagus cuniculus 50-58 2994494-6 1985 In the presence of lanthanum (5-50 microM) or verapamil (20-200 microM), PTH inhibited ouabain-sensitive O2 consumption by 21.3 +/- 3.4% (P less than 0.025) and 33.9 +/- 5.5% (P less than 0.025), respectively. Lanthanum 19-28 parathyroid hormone Oryctolagus cuniculus 73-76 6137535-4 1983 The K+-induced increase in tissue calcium content and 45Ca uptake determined by the lanthanum method was significantly reduced in the presence of Cd2+ (0.5 mM) and the contractions of the glycerolated taenia coli were inhibited with increasing Cd2+ (0.001-0.5 mM). Lanthanum 84-93 T-cell surface antigen CD2 Cavia porcellus 146-149 6253264-5 1980 Aldosterone production by glomerulosa cells in response to angiotensin II or potassium was also decreased by lanthanum and verapamil, with no change in the concentration of angiotensin II required for half-maximal stimulation of steroidogenesis. Lanthanum 109-118 angiotensinogen Homo sapiens 59-73 6983617-8 1982 When the muscle preparation was treated with neuraminidase, the twitch inhibition caused by lanthanum was strongly depressed. Lanthanum 92-101 neuraminidase 1 Homo sapiens 45-58 6264806-1 1981 The effects of Na+-K+-ATPase inhibition by ouabain and blockage of Ca2+ influx into the cell by verapamil and lanthanum on the response of isolated rat adrenal glomerulosa cells to angiotensin II, ACTH, and K+ were studied. Lanthanum 110-119 angiotensinogen Rattus norvegicus 181-195 6264806-6 1981 Lanthanum decreased basal and angiotensin II, ACTH, and K+ induced aldosterone secretion. Lanthanum 0-9 angiotensinogen Rattus norvegicus 30-44 7251863-7 1981 This concentration of lanthanum suppressed gastrin stimulation by 40 +/- 7% and histamine stimulation by only 12 +/- 9%. Lanthanum 22-31 gastrin Canis lupus familiaris 43-50 6978626-0 1981 Ultrastructural studies on the mode of action of antidiuretic hormone: the inhibitory effect of lanthanum. Lanthanum 96-105 arginine vasopressin Homo sapiens 49-69 6253266-6 1980 The calcium antagonists, verapamil and lanthanum, caused concentration-dependent inhibition of the actions of GnRH, with half-maximal blockade values of 10(-5) and 3 X 10(-6) M, respectively, and had no effect on basal LH release. Lanthanum 39-48 gonadotropin releasing hormone 1 Rattus norvegicus 110-114 7452489-5 1980 Lanthanum, a known calcium antagonists in other tissue systems, mimicked the effect of calcium on calmodulin binding. Lanthanum 0-9 calmodulin 1 Rattus norvegicus 98-108 7452489-7 1980 Lanthanum, but not calcium, inhibited calmodulin release from a non-EGTA-treated preparation. Lanthanum 0-9 calmodulin 1 Rattus norvegicus 38-48 7452489-8 1980 This difference in action between calcium and lanthanum suggests that they mediate calmodulin binding in an independent manner. Lanthanum 46-55 calmodulin 1 Rattus norvegicus 83-93 7399975-7 1980 Lanthanum was found in large amounts in the fibrin clot obtained after treating the plasma with thrombin. Lanthanum 0-9 prothrombin Oryctolagus cuniculus 96-104 7192108-2 1980 administration of praseodymium, cerium and lanthanum (3 to 14 mg/kg) produced a dose-dependent increase in the serum activities of GOT, GPT and SDH. Lanthanum 43-52 glutamic--pyruvic transaminase Rattus norvegicus 136-139 7192108-2 1980 administration of praseodymium, cerium and lanthanum (3 to 14 mg/kg) produced a dose-dependent increase in the serum activities of GOT, GPT and SDH. Lanthanum 43-52 serine dehydratase Rattus norvegicus 144-147 572035-0 1979 Blockade of Ca2+ dependent rat atrial slow action potentials by adenosine and lanthanum. Lanthanum 78-87 carbonic anhydrase 2 Rattus norvegicus 12-15 219122-8 1979 Lanthanum ion, 0.1 to 1 mM, in the presence of 1 mM Ca2+ inhibited the production of superoxide by FMLP 4 X 10(-8 ) M. Over the concentration range 3.3 X 10(-5 M to 3 X 10(-4 M, verapamil, a drug which selectively blocks the calcium channel, caused a dose-dependent inhibition of superoxide production and calcium-45 uptake in response to FMLP. Lanthanum 0-9 formyl peptide receptor 1 Homo sapiens 99-103 219122-8 1979 Lanthanum ion, 0.1 to 1 mM, in the presence of 1 mM Ca2+ inhibited the production of superoxide by FMLP 4 X 10(-8 ) M. Over the concentration range 3.3 X 10(-5 M to 3 X 10(-4 M, verapamil, a drug which selectively blocks the calcium channel, caused a dose-dependent inhibition of superoxide production and calcium-45 uptake in response to FMLP. Lanthanum 0-9 formyl peptide receptor 1 Homo sapiens 339-343 455841-7 1979 Calcitonin caused a marked accumulation of lanthanum around osteocytes and in bone fluid adjacent to lining cells. Lanthanum 43-52 calcitonin-related polypeptide alpha Rattus norvegicus 0-10 365654-0 1979 Effects of calcium, lanthanum, and bicarbonate ion on epinephrine modification of insulin release in vitro. Lanthanum 20-29 insulin Homo sapiens 82-89 365654-2 1979 Lanthanum inhibits insulin secretion stimulated by glucose and by acetylcholine to basal levels. Lanthanum 0-9 insulin Homo sapiens 19-26 365654-3 1979 Epinephrine and lanthanum have additive effects in inhibiting insulin secretion to glucose stimulation. Lanthanum 16-25 insulin Homo sapiens 62-69 365654-5 1979 In the presence of bicarbonate, lanthanum blocks the priming effect of epinephrine on insulin secretion. Lanthanum 32-41 insulin Homo sapiens 86-93 415132-2 1977 The effects of external medium calcium concentration, the ionophore A(23187) and lanthanum on the rate of renin release in vitro were studied with particular emphasis on results obtained from isolated superfused glomeruli of rat kidneys.2. Lanthanum 81-90 renin Rattus norvegicus 106-111 103759-4 1978 Nevertheless, by using a lanthanum displacement protocol to follow the influx of 45Ca2+ it is shown that LH-RH stimulation does induce an influx of extracellular Ca2+. Lanthanum 25-34 gonadotropin releasing hormone 1 Homo sapiens 105-110 415132-11 1977 Addition of lanthanum (1 or 0.05 mM) to calcium-containing as well as calcium-free superfusate resulted in a significant depression of renin release. Lanthanum 12-21 renin Rattus norvegicus 135-140 612143-0 1977 Serum ornithine carbamoyltransferase (OCT) in rats poisoned with lanthanum, cerium and praseodymium. Lanthanum 65-74 ornithine transcarbamylase Rattus norvegicus 6-36 612143-0 1977 Serum ornithine carbamoyltransferase (OCT) in rats poisoned with lanthanum, cerium and praseodymium. Lanthanum 65-74 ornithine transcarbamylase Rattus norvegicus 38-41 612143-1 1977 Serum ornithine carbamoyltransferase (OCT) in rats poisoned with lanthanum, cerium and praseodymium. Lanthanum 65-74 ornithine transcarbamylase Rattus norvegicus 6-36 612143-1 1977 Serum ornithine carbamoyltransferase (OCT) in rats poisoned with lanthanum, cerium and praseodymium. Lanthanum 65-74 ornithine transcarbamylase Rattus norvegicus 38-41 612143-4 1977 The serum ornithine carbamoyltransferase in relation to doses of lanthanum, cerium and praseodymium, administered intravenously as chlorides, was investigated. Lanthanum 65-74 ornithine transcarbamylase Rattus norvegicus 10-40 13401-0 1977 The effect of lanthanum on renin secretion and renal vasoconstriction. Lanthanum 14-23 renin Homo sapiens 27-32 4366347-0 1974 Lanthanum inhibition of the action of oxytocin on the water permeability of the frog urinary bladder: effect on the serosal and the apical membrane. Lanthanum 0-9 oxytocin/neurophysin I prepropeptide Homo sapiens 38-46 16659673-3 1976 Maximum ATPase activity in the presence of Mg(2+) and K(+) was at pH 6.5 and 40 C. Calcium and lanthanum (<0.5 mm) were inhibitors of ATPase, but only in the presence of Mg(2+). Lanthanum 95-104 ATPase Zea mays 8-14 16659673-3 1976 Maximum ATPase activity in the presence of Mg(2+) and K(+) was at pH 6.5 and 40 C. Calcium and lanthanum (<0.5 mm) were inhibitors of ATPase, but only in the presence of Mg(2+). Lanthanum 95-104 ATPase Zea mays 137-143 942475-0 1976 Inhibition of rat liver catechol-O-methyltransferase by lanthanum. Lanthanum 56-65 catechol-O-methyltransferase Rattus norvegicus 24-52 1249752-0 1976 The effects of lanthanum and thulium on the mechanical responses of rat vas deferens. Lanthanum 15-24 arginine vasopressin Rattus norvegicus 72-75 34058500-0 2021 Biotransformation of soluble-insoluble lanthanum species and its induced NLRP3 inflammasome activation and chronic fibrosis. Lanthanum 39-48 NLR family pyrin domain containing 3 Homo sapiens 73-78 1077784-0 1975 Blockade of renin release by lanthanum. Lanthanum 29-38 renin Rattus norvegicus 12-17 1077784-2 1975 The effects of lanthanum on renin release and renal vasoconstriction were studied in the isolated perfused rat kidney. Lanthanum 15-24 renin Rattus norvegicus 28-33 1077784-6 1975 Lanthanum prevented isoprenaline-induced and glucagon-induced stimulation of renin secretion. Lanthanum 0-9 renin Rattus norvegicus 77-82 4128659-2 1973 In the concentration range 1 nM to 1 muM, lanthanum inhibited the calcium-dependent component of anaphylactic histamine release, but was without effect on the component which was independent of calcium.2. Lanthanum 42-51 latexin Homo sapiens 37-40 4128659-8 1973 At concentrations of 10 muM and greater, lanthanum induced a release of histamine in the absence of antigen.7. Lanthanum 41-50 latexin Homo sapiens 24-27 4802769-0 1973 [Effect in vitro of lanthanum, yttrium and cerium chlorides on the 1st phase of the thrombin-fibrinogen reaction]. Lanthanum 20-29 coagulation factor II, thrombin Homo sapiens 84-92 33797709-7 2022 Interestingly sevelamer, lanthanum, iron-based phosphate binders, and iron supplement significantly lowered FGF23 levels. Lanthanum 25-34 fibroblast growth factor 23 Homo sapiens 108-113 33705787-0 2021 Effects of PI3K/AKT/mTOR Pathway Regulation of HIF-1alpha on Lanthanum-Induced Neurotoxicity in Rats. Lanthanum 61-70 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 47-57 33705787-1 2021 This study examined the effects of the AKT/mTOR/HIF-1alpha signaling pathway on learning and memory in offspring rats induced by lanthanum from neuroethology and molecular biology perspectives. Lanthanum 129-138 AKT serine/threonine kinase 1 Rattus norvegicus 39-42 33705787-1 2021 This study examined the effects of the AKT/mTOR/HIF-1alpha signaling pathway on learning and memory in offspring rats induced by lanthanum from neuroethology and molecular biology perspectives. Lanthanum 129-138 hypoxia inducible factor 1 subunit alpha Rattus norvegicus 48-58 32860924-3 2020 The CS/LaP/siEGFR NPs exhibited significant biological activities in human colorectal cancer HT-29 cells by the synergistic effects of siEGFRs and lanthanum ions, such as downregulation of EGFR and upregulation of miR-34a. Lanthanum 147-156 LAP Homo sapiens 7-10 33359004-8 2021 Further results showed that lanthanum treatment significantly decreased plasma neurotransmitter levels of acetylcholine and norepinephrine as well as the number of neurons in the CA1 area of the hippocampus. Lanthanum 28-37 carbonic anhydrase 1 Rattus norvegicus 179-182 33243512-0 2021 Protective effects of rare earth lanthanum on acute ethanol-induced oxidative stress in mice via Keap 1/Nrf2/p62 activation. Lanthanum 33-42 kelch-like ECH-associated protein 1 Mus musculus 97-103 33243512-0 2021 Protective effects of rare earth lanthanum on acute ethanol-induced oxidative stress in mice via Keap 1/Nrf2/p62 activation. Lanthanum 33-42 nuclear factor, erythroid derived 2, like 2 Mus musculus 104-108 33243512-0 2021 Protective effects of rare earth lanthanum on acute ethanol-induced oxidative stress in mice via Keap 1/Nrf2/p62 activation. Lanthanum 33-42 nucleoporin 62 Mus musculus 109-112 32860924-3 2020 The CS/LaP/siEGFR NPs exhibited significant biological activities in human colorectal cancer HT-29 cells by the synergistic effects of siEGFRs and lanthanum ions, such as downregulation of EGFR and upregulation of miR-34a. Lanthanum 147-156 epidermal growth factor receptor Homo sapiens 13-17 32450354-1 2020 In the present work, talc (a low-cost clay) encapsulated salts alginate (TAL) beads were synthesized by cross-linking with lanthanum ion and tested for phosphate adsorption. Lanthanum 123-132 transaldolase 1 Homo sapiens 73-76 33206094-7 2020 In conclusion, this study indicated that lanthanum caused endothelial barrier hyperpermeability accompanied by loss of VE-cadherin and rearrangement of the actin cytoskeleton though intracellular Ca2+-mediated RhoA/ROCK and MLCK pathways. Lanthanum 41-50 actin-2 Raphanus sativus 156-161 33206094-7 2020 In conclusion, this study indicated that lanthanum caused endothelial barrier hyperpermeability accompanied by loss of VE-cadherin and rearrangement of the actin cytoskeleton though intracellular Ca2+-mediated RhoA/ROCK and MLCK pathways. Lanthanum 41-50 ras homolog family member A Mus musculus 210-214 32901861-0 2020 Fortified phosphorus-lowering treatment through administration of lanthanum protects against vascular calcification via regulation of FGF23 in chronic kidney disease. Lanthanum 66-75 fibroblast growth factor 23 Homo sapiens 134-139 32450354-3 2020 The combined effect of talc and lanthanum improved phosphate removal performance of TAL beads. Lanthanum 32-41 transaldolase 1 Homo sapiens 84-87 33384725-11 2020 Successful coil embolization rate for LAs with internal diameter longer than 2.0 mm and aortic diameter less than 36.2 mm was 90% (72 among 80 LAs). Lanthanum 38-41 coilin Homo sapiens 11-15 32777140-8 2020 Patients with exercise intolerance (METs < 8) had lower LAS-s (P < .001), LAS-e (P < .01), and LAS-a (P < .05) values compared to those with METs >= 8. Lanthanum 56-59 ETS variant transcription factor 3 Homo sapiens 36-40 31408166-0 2020 Cadmium versus Lanthanum Effects on Spontaneous Electrical Activity and Expression of Connexin Isoforms Cx26, Cx36, and Cx45 in the Human Fetal Cortex. Lanthanum 15-24 gap junction protein beta 2 Homo sapiens 104-108 32727047-1 2020 The piezoelectric properties of lanthanum-modified lead zirconate titanate Pb1-xLax(Zr0.52Ti0.48)1-x/4O3 thin films, with x = 0, 3 and 12 mol% La, were studied by in situ synchrotron X-ray diffraction under direct (DC) and alternating (AC) electric fields, with AC frequencies covering more than four orders of magnitude. Lanthanum 32-41 polybromo 1 Homo sapiens 75-78 31833589-3 2020 A novel modified NaY zeolite (SMZ-La) with hexadecyl trimethyl ammonium bromide (HDTMA) and lanthanum (La) as modifying agents for NO3 - -N adsorption was investigated in this study. Lanthanum 92-101 NBL1, DAN family BMP antagonist Homo sapiens 131-134 32503358-2 2020 The modification consisted of the adsorption of lanthanum(III) ions on the Arsen Xnp surface. Lanthanum 48-57 ATRX chromatin remodeler Homo sapiens 81-84 31408166-0 2020 Cadmium versus Lanthanum Effects on Spontaneous Electrical Activity and Expression of Connexin Isoforms Cx26, Cx36, and Cx45 in the Human Fetal Cortex. Lanthanum 15-24 gap junction protein delta 2 Homo sapiens 110-114 31408166-0 2020 Cadmium versus Lanthanum Effects on Spontaneous Electrical Activity and Expression of Connexin Isoforms Cx26, Cx36, and Cx45 in the Human Fetal Cortex. Lanthanum 15-24 gap junction protein gamma 1 Homo sapiens 120-124 31733625-4 2019 Here we show that ET coupling in HEK293 cells transfected with wt Cav1.2 or the Timothy mutant Cav1.2G406R is mediated by substituting Ca2+ with the impermeable lanthanum (La3+). Lanthanum 161-170 calcium voltage-gated channel subunit alpha1 C Homo sapiens 66-72 32045211-2 2020 Here, we report A-site lanthanum-doped oxygen-rich quinary oxide CaLaScRuO6+delta synthesized by adopting the solid-state reaction method and characterized by various techniques such as powder X-ray diffraction, neutron diffraction, energy-dispersive X-ray spectroscopy, inductively coupled plasma-atomic emission spectrometry, Raman spectroscopy, and temperature-programmed reduction in the presence of a hydrogen atmosphere (H2-TPR). Lanthanum 23-32 translocated promoter region, nuclear basket protein Homo sapiens 430-433 31837822-7 2020 The intravenous melanoma model shows that LaOI with low dose (1 mg mL-1) could significantly inhibit the tumor growth without side toxicity, relative to pure DOX. Lanthanum 42-46 L1 cell adhesion molecule Mus musculus 67-71 30848866-1 2019 Strontium-substituted lanthanum cobaltite (La0.8 Sr0.2 CoO3 ) matrix-stabilized Co0 /CoII catalytic sites were prepared, which present tunable C-O and C-C hydrogenolysis activity for the vapor-phase upgrading of oxygenated arenes. Lanthanum 22-31 mitochondrially encoded cytochrome c oxidase II Homo sapiens 85-89 31136876-4 2019 Here, we reported that seedlings grown in a medium containing 150 muM lanthanum exhibited increased overproduction of reactive oxygen species (ROS) and lipid peroxidation together with increased Chlorophyll degradation, and activity of chlorophyllase, proline dehydrogenase and glycolate oxidase (GOx), and decreased photosynthesis and growth. Lanthanum 70-79 peroxisomal (S)-2-hydroxy-acid oxidase GLO1 Solanum lycopersicum 278-295 31136876-4 2019 Here, we reported that seedlings grown in a medium containing 150 muM lanthanum exhibited increased overproduction of reactive oxygen species (ROS) and lipid peroxidation together with increased Chlorophyll degradation, and activity of chlorophyllase, proline dehydrogenase and glycolate oxidase (GOx), and decreased photosynthesis and growth. Lanthanum 70-79 peroxisomal (S)-2-hydroxy-acid oxidase GLO1 Solanum lycopersicum 297-300 30741951-5 2019 In our study, we obtained bovine alpha-lactalbumin complexed with lanthanum ion (La3+-B-alpha-LA) and determined its high resolution crystal structure. Lanthanum 66-75 lactalbumin alpha Bos taurus 33-50 31010215-2 2019 In this paper, lanthanum(III) ions were introduced to the structure of chitosan via an encapsulation technique and the obtained hydrogel (La-CTS) was used for the elimination of the excess of B(III) from modelling solutions. Lanthanum 15-24 calcium voltage-gated channel subunit alpha1 B Homo sapiens 192-198 30688345-2 2019 In order to accelerate bone defects especially in patients with osteoporosis or other metabolic diseases, we firstly constructed lanthanum-doped mesoporous calcium silicate/chitosan (La-MCS/CTS) scaffolds by freeze-drying technology. Lanthanum 129-138 transthyretin Homo sapiens 183-193 30741951-6 2019 The natural calcium binding site of bovine alpha-lactalbumin is replaced by lanthanum. Lanthanum 76-85 lactalbumin alpha Bos taurus 43-60 29876795-9 2019 Taken together, this study demonstrated that postnatal lanthanum exposure caused leakage of BBB in young rats, partially attributed to upregulation of MMP-9 and reduction of junctional proteins expression. Lanthanum 55-64 matrix metallopeptidase 9 Rattus norvegicus 151-156 29992101-3 2018 Here we account for the evaluation of a lanthanum-based flocculation method to concentrate bacteria from water samples, applying four different bacterial species in tap water as well as river water. Lanthanum 40-49 nuclear RNA export factor 1 Homo sapiens 165-168 30004159-6 2018 AIM: This study sought to determine whether FLI could distinguish false-positive FVIII inhibitor results related to LAs from clinically relevant FVIII inhibitors in HA patients. Lanthanum 116-119 coagulation factor VIII Homo sapiens 81-86 29781615-1 2018 We report a superconducting transition in a LaO epitaxial thin film with the superconducting transition onset temperature ( Tc) at around 5 K. This Tc is higher than those of other lanthanum monochalcogenides and opposite to their chemical trend: Tc = 0.84, 1.02, and 1.48 K for LaX (X = S, Se, Te), respectively. Lanthanum 181-190 interleukin 4 induced 1 Homo sapiens 44-47 30361718-7 2018 Las concentraciones sericas de IL-1beta disminuyeron unicamente con la dieta hipocalorica normoproteica (p = 0.02). Lanthanum 0-3 interleukin 1 beta Homo sapiens 31-39 29132107-4 2018 Introduction of lanthanum cations leads to a reduction in BET surface area, mainly due to a decrease in the area of micropores and reduction in the pore volume. Lanthanum 16-25 bet Drosophila melanogaster 58-61 27928636-5 2017 Mean serum FGF23 level was significantly decreased after a 24-week treatment with lanthanum (8677.5 +- 7490.0 vs. 4692.8 +- 5348.3 pg/mL, p = 0.013, n = 13), but not with calcium (n = 12). Lanthanum 82-91 fibroblast growth factor 23 Homo sapiens 11-16 28148453-5 2017 The experimental results obtained after factorial design indicate optimum adsorption parameters as pH 6, contact time 60 min, and temperature 298 K, when the equilibrium concentration of lanthanum was 250 mg L-1, and the experimental adsorption capacity obtained was 31.58 mg g-1. Lanthanum 187-196 immunoglobulin kappa variable 1-16 Homo sapiens 208-211 27928636-6 2017 The reduction of serum hepcidin in lanthanum group was positively correlated with the decrement of serum phosphate (r = 0.631, p = 0.021) and serum hsCRP (r = 0.670, p = 0.012) levels, respectively. Lanthanum 35-44 hepcidin antimicrobial peptide Homo sapiens 23-31 27928636-8 2017 CONCLUSIONS: In summary, a decrease in serum FGF23 levels and a trend of decline in hepcidin levels were observed only in lanthanum group. Lanthanum 122-131 fibroblast growth factor 23 Homo sapiens 45-50 27928636-8 2017 CONCLUSIONS: In summary, a decrease in serum FGF23 levels and a trend of decline in hepcidin levels were observed only in lanthanum group. Lanthanum 122-131 hepcidin antimicrobial peptide Homo sapiens 84-92 28747739-0 2017 Spin pump and probe in lanthanum strontium manganite/platinum bilayers. Lanthanum 23-32 spindlin 1 Homo sapiens 0-4 28056417-0 2017 Analysis of the combined effects of lanthanum and acid rain, and their mechanisms, on nitrate reductase transcription in plants. Lanthanum 36-45 inducible nitrate reductase [NADH] 1 Glycine max 86-103 28017670-3 2017 In order to determine whether TRPA1 activation by LAs is specific to amide-types, we examined the actions of tetracaine, another ester-type LA, and other amide-type LAs on glutamatergic spontaneous excitatory transmission in SG neurons by focusing on TRP activation. Lanthanum 50-53 transient receptor potential cation channel, subfamily A, member 1 Rattus norvegicus 30-35 32263846-3 2017 Herein, we report the ultratrace molecular detection using a low-adhesive superhydrophobic surface-enhanced Raman spectroscopy (LAS-SERS) substrate fabricated by femtosecond laser ablation. Lanthanum 128-131 seryl-tRNA synthetase 1 Homo sapiens 132-136 32263846-4 2017 The LAS-SERS substrate has good characteristics, including a contact angle as high as 154 , a contact angle hysteresis below 5 , and a simulated Raman signal enhancement factor of up to 6 x 106. Lanthanum 4-7 seryl-tRNA synthetase 1 Homo sapiens 8-12 32263846-5 2017 Compared to the previously developed superhydrophobic SERS (S-SERS) methods, the low-adhesive nature of the LAS-SERS method can greatly reduce the final contact area, thus significantly enhancing the detection limit. Lanthanum 108-111 seryl-tRNA synthetase 1 Homo sapiens 54-58 32263846-5 2017 Compared to the previously developed superhydrophobic SERS (S-SERS) methods, the low-adhesive nature of the LAS-SERS method can greatly reduce the final contact area, thus significantly enhancing the detection limit. Lanthanum 108-111 seryl-tRNA synthetase 1 Homo sapiens 62-66 32263846-5 2017 Compared to the previously developed superhydrophobic SERS (S-SERS) methods, the low-adhesive nature of the LAS-SERS method can greatly reduce the final contact area, thus significantly enhancing the detection limit. Lanthanum 108-111 seryl-tRNA synthetase 1 Homo sapiens 62-66 32263846-6 2017 In our experiments, the final contact area of the LAS-SERS substrate was reduced by 19.5 times, corresponding to an 88.1 times increase in the concentration effect, as compared to the highly adhesive S-SERS substrates fabricated using the same technique. Lanthanum 50-53 seryl-tRNA synthetase 1 Homo sapiens 54-58 32263846-6 2017 In our experiments, the final contact area of the LAS-SERS substrate was reduced by 19.5 times, corresponding to an 88.1 times increase in the concentration effect, as compared to the highly adhesive S-SERS substrates fabricated using the same technique. Lanthanum 50-53 seryl-tRNA synthetase 1 Homo sapiens 202-206 27549211-13 2016 The results indicate that the rhl QSS affects the virulence potential of P. aeruginosa and that, despite the presence of the las QSS, mutant strains exhibited reduced pathology. Lanthanum 125-128 ATP-dependent RNA helicase RhlB Pseudomonas aeruginosa PAO1 30-33