PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 26718746-5 2016 The effect of HAO472 on NF-kappaB signaling pathway in lymphocytes was also invesigated. HAO472 14-20 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 24-33 26718746-7 2016 HAO472 also reduced TNF-alpha, IFN-gamma, IL-17A, iNOS/COX-2 and lymphocyte proliferation. HAO472 0-6 tumor necrosis factor Mus musculus 20-29 26718746-7 2016 HAO472 also reduced TNF-alpha, IFN-gamma, IL-17A, iNOS/COX-2 and lymphocyte proliferation. HAO472 0-6 interferon gamma Mus musculus 31-40 26718746-7 2016 HAO472 also reduced TNF-alpha, IFN-gamma, IL-17A, iNOS/COX-2 and lymphocyte proliferation. HAO472 0-6 nitric oxide synthase 2, inducible Mus musculus 50-54 26718746-7 2016 HAO472 also reduced TNF-alpha, IFN-gamma, IL-17A, iNOS/COX-2 and lymphocyte proliferation. HAO472 0-6 cytochrome c oxidase II, mitochondrial Mus musculus 55-60 26718746-9 2016 CONCLUSION: HAO472 has positive effects on TNBS-induced colitis by modulating the subsets and functions of lymphocytes, suppressing inflammation and inhibiting the nuclear translocation of NF-kappaB p65 subunits. HAO472 12-18 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 189-198 26718746-9 2016 CONCLUSION: HAO472 has positive effects on TNBS-induced colitis by modulating the subsets and functions of lymphocytes, suppressing inflammation and inhibiting the nuclear translocation of NF-kappaB p65 subunits. HAO472 12-18 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 199-202 35224406-0 2022 Binding Studies of the Prodrug HAO472 to SARS-Cov-2 Nsp9 and Variants. HAO472 31-37 ORF1a polyprotein;ORF1ab polyprotein Severe acute respiratory syndrome coronavirus 2 52-56