PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
22777817-0	2012	Targeting of CD22-positive B-cell lymphoma cells by synthetic divalent sialic acid analogues.	divalent	62-70	CD22 molecule	Homo sapiens	13-17
19049969-3	2009	CutA is a ubiquitous trimeric protein, homologous to the bacterial CutA1 protein that belongs to an operon involved in resistance to divalent ions ("copper tolerance A").	divalent	133-141	cutA divalent cation tolerance homolog	Homo sapiens	0-4
19625771-1	2009	Depolarization-induced entry of divalent ions into skeletal muscle has been attributed to a process termed Excitation-Coupled Ca(2+) Entry (ECCE), which is hypothesized to require the interaction of the ryanodine receptor (RyR1), the L-type Ca(2+) channel (DHPR) and another unidentified cation channel.	divalent	32-40	ryanodine receptor 1	Homo sapiens	223-227
19625771-1	2009	Depolarization-induced entry of divalent ions into skeletal muscle has been attributed to a process termed Excitation-Coupled Ca(2+) Entry (ECCE), which is hypothesized to require the interaction of the ryanodine receptor (RyR1), the L-type Ca(2+) channel (DHPR) and another unidentified cation channel.	divalent	32-40	quinoid dihydropteridine reductase	Homo sapiens	257-261
3756201-5	1986	This phospholipase A2 was active only in the presence of divalent cations (Ca2+ greater than Sr2+ greater than Mg2+ = 0), required albumin for optimal activity and exhibited exclusive positional specificity for the acyl ester bond at the 2-position of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine.	divalent	57-65	phospholipase A2 group IB	Homo sapiens	5-21
16426630-1	2006	Isothermal calorimetry was used to determine enthalpy changes for interaction of divalent cobalt, nickel, copper, and zinc chlorides with silica gel functionalized with vanillin, Sil-Van.	divalent	81-89	STIL centriolar assembly protein	Homo sapiens	179-182
3480286-7	1987	The activity of p93 was dependent on Mg2+ or Mn2+, whereas p60 was dependent on Mg2+; however, the activity of p60 was stimulated in a synergistic manner by the presence of both Mg2+ and Mn2+, whereas the activity of p93 was not enhanced further by the combination of divalent ions.	divalent	268-276	sequestosome 1	Homo sapiens	111-114
3558405-6	1987	The key difference between the binding of these divalent ions is that Ca(II) apparently causes a specific conformational change reflected by the cooperativity observed in the Ca(II) titration.	divalent	48-56	carbonic anhydrase 2	Bos taurus	70-76
3558405-6	1987	The key difference between the binding of these divalent ions is that Ca(II) apparently causes a specific conformational change reflected by the cooperativity observed in the Ca(II) titration.	divalent	48-56	carbonic anhydrase 2	Bos taurus	175-181
28250280-0	2017	Species Difference in Sensitivity of Human and Mouse P2X7 Receptors to Inhibitory Effects of Divalent Metal Cations.	divalent	93-101	purinergic receptor P2X, ligand-gated ion channel, 7	Mus musculus	53-57
29193802-1	2018	A MUC1 anticancer vaccine equipped with covalently linked divalent mannose ligands was found to improve the antigen uptake and presentation by targeting mannose-receptor-positive macrophages and dendritic cells.	divalent	58-66	mucin 1, cell surface associated	Homo sapiens	2-6
6615519-2	1983	Results of studies reported here indicate that the toxicity of a series of divalent metal cations correlates well with the metals" ability to inhibit the Ca2+ receptor protein calmodulin (r = 0.986).	divalent	75-83	calmodulin 1	Homo sapiens	176-186
18631460-0	1969	An electron microscope study of the influence of divalent ions on myosin filament formation in chicken gizzard extracts and homogenates.	divalent	49-57	myosin, heavy chain 15	Gallus gallus	66-72
33890594-1	2021	We report herein the synthesis, structural characterization and electrocatalytic properties of three new coordination polymers, resulting from the combination of divalent metal (Ca2+, Cd2+ or Co2+) salts with (2-carboxyethyl)(phenyl)phosphinic acid.	divalent	162-170	complement C2	Homo sapiens	192-195
28250280-2	2017	It is reported that divalent metal cations (DMCs) inhibit P2X7R activation and that there are species differences in their inhibitory effects.	divalent	20-28	purinergic receptor P2X 7	Homo sapiens	58-63