PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 23453304-0 2013 Antihyperglycemic and sub-chronic antidiabetic actions of morolic and moronic acids, in vitro and in silico inhibition of 11beta-HSD 1. moronic acid 70-83 hydroxysteroid 11-beta dehydrogenase 1 Rattus norvegicus 122-134 26961283-0 2016 In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives. moronic acid 92-104 protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus 23-29 26961283-1 2016 Six derivatives (1-6) of moronic acid were semi-synthesized and their in vitro protein tyrosine phosphatase 1B (PTP-1B) inhibition activity assessed. moronic acid 25-37 protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus 79-110 26961283-1 2016 Six derivatives (1-6) of moronic acid were semi-synthesized and their in vitro protein tyrosine phosphatase 1B (PTP-1B) inhibition activity assessed. moronic acid 25-37 protein tyrosine phosphatase, non-receptor type 1 Rattus norvegicus 112-118 23453304-9 2013 In conclusion, morolic and moronic acids have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11beta-HSD 1 as indicated by in vitro and in silico studies. moronic acid 27-40 hydroxysteroid 11-beta dehydrogenase 1 Rattus norvegicus 251-263 19969023-2 2010 Our immunoblotting and flow cytometry analyses find that moronic acid, found in galls of Rhus chinensis and Brazilian propolis, at 10microM inhibits the expression of Rta, Zta, and an EBV early protein, EA-D, after lytic induction with sodium butyrate. moronic acid 57-69 MAS related GPR family member F Homo sapiens 167-170 19969023-2 2010 Our immunoblotting and flow cytometry analyses find that moronic acid, found in galls of Rhus chinensis and Brazilian propolis, at 10microM inhibits the expression of Rta, Zta, and an EBV early protein, EA-D, after lytic induction with sodium butyrate. moronic acid 57-69 collagen like tail subunit of asymmetric acetylcholinesterase Homo sapiens 203-207 19969023-3 2010 This study also finds that moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that moronic acid interferes with the function of Rta. moronic acid 27-40 MAS related GPR family member F Homo sapiens 66-69 19969023-3 2010 This study also finds that moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that moronic acid interferes with the function of Rta. moronic acid 27-40 MAS related GPR family member F Homo sapiens 110-113 19969023-3 2010 This study also finds that moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that moronic acid interferes with the function of Rta. moronic acid 27-40 MAS related GPR family member F Homo sapiens 110-113 19969023-3 2010 This study also finds that moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that moronic acid interferes with the function of Rta. moronic acid 27-39 MAS related GPR family member F Homo sapiens 66-69 19969023-3 2010 This study also finds that moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that moronic acid interferes with the function of Rta. moronic acid 27-39 MAS related GPR family member F Homo sapiens 110-113 19969023-3 2010 This study also finds that moronic acids inhibits the capacity of Rta to activate a promoter that contains an Rta-response element, indicating that moronic acid interferes with the function of Rta. moronic acid 27-39 MAS related GPR family member F Homo sapiens 110-113 19969023-6 2010 Because the expression of Zta, EA-D and many EBV lytic genes depends on Rta, the treatment of P3HR1 cells with moronic acid substantially reduces the numbers of EBV particles produced by the cells after lytic induction. moronic acid 111-123 collagen like tail subunit of asymmetric acetylcholinesterase Homo sapiens 31-35 19969023-6 2010 Because the expression of Zta, EA-D and many EBV lytic genes depends on Rta, the treatment of P3HR1 cells with moronic acid substantially reduces the numbers of EBV particles produced by the cells after lytic induction. moronic acid 111-123 MAS related GPR family member F Homo sapiens 72-75