PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
18568072-6	2005	m-Chlorophenylpyperazine (m-CPP), an agonist to 5HT1A, 5HT1D, and 5HT2C receptors, and which also blocks 5HT3 receptors, exacerbates OC symptoms.	mecoprop	26-31	5-hydroxytryptamine receptor 1A	Homo sapiens	48-53
18568072-6	2005	m-Chlorophenylpyperazine (m-CPP), an agonist to 5HT1A, 5HT1D, and 5HT2C receptors, and which also blocks 5HT3 receptors, exacerbates OC symptoms.	mecoprop	26-31	5-hydroxytryptamine receptor 1D	Homo sapiens	55-60
8032949-7	1994	Microiontophoretically applied 1-(3-chlorophenyl)piperazine (mCPP), a 5-HT1B agonist inhibited the orthodromic spike elicited by vestibular nerve stimulation and glutamate-induced firing in only a small number of the LVN neurons.	mecoprop	61-65	5-hydroxytryptamine receptor 1B	Felis catus	70-76
9543230-1	1998	1-(Meta-chloro)phenylpiperazine (m-CPP) is a 5-HT receptor agonist which has been purported to be relatively selective for the 5-HT2C receptor.	mecoprop	33-38	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	127-142
7965773-8	1994	Partial inactivation of 5-HT2A receptors with phenoxybenzamine decreased the maximal effects of mCPP and TFMPP but did not eliminate agonist activity.	mecoprop	96-100	5-hydroxytryptamine receptor 2A	Homo sapiens	24-30
7965773-9	1994	Thus mCPP and TFMPP are partial agonists at 5-HT2A receptors in GF6 cells, and these agonist properties are retained even under conditions where receptor density is comparable to that of cerebral cortex.	mecoprop	5-9	5-hydroxytryptamine receptor 2A	Homo sapiens	44-50
7965773-10	1994	Although it has not yet been demonstrated that mCPP and TFMPP are agonists at central 5-HT2A receptors, this possibility should be considered when evaluating in vivo effects of these drugs.	mecoprop	47-51	5-hydroxytryptamine receptor 2A	Homo sapiens	86-92
2150180-9	1990	Forepaw treading in rats induced by the 5-HT1A-agonist 8-OH-DPAT was attenuated by the 5-HT1C-agonists MK 212 and mCPP.	mecoprop	114-118	5-hydroxytryptamine receptor 1A	Rattus norvegicus	40-46
7694158-8	1993	In A9 cells which were incubated 24 h with the 5-HT1C receptor agonist meta chlorophenylpiperazine hydrochloride (mCPP), 5-HT-induced responses were reduced by 23% of the vehicle pretreated control value.	mecoprop	114-118	5-hydroxytryptamine receptor 2C	Rattus norvegicus	47-53
7912626-16	1994	These results indicate that SB 200646A has in vivo efficacy and that 5-HT2C or 5-HT2B receptors are indeed likely to mediate mCPP-induced hypolocomotion, hypophagia and anxiogenesis.	mecoprop	125-129	5-hydroxytryptamine receptor 2C	Rattus norvegicus	69-75
7912626-16	1994	These results indicate that SB 200646A has in vivo efficacy and that 5-HT2C or 5-HT2B receptors are indeed likely to mediate mCPP-induced hypolocomotion, hypophagia and anxiogenesis.	mecoprop	125-129	5-hydroxytryptamine receptor 2B	Rattus norvegicus	79-85
1387963-0	1992	Etoperidone, trazodone and MCPP: in vitro and in vivo identification of serotonin 5-HT1A (antagonistic) activity.	mecoprop	27-31	5-hydroxytryptamine receptor 1A	Rattus norvegicus	82-88
1387963-1	1992	The Ki values for etoperidone, trazodone and MCPP (m-chlorophenylpiperazine dihydrochloride) at 5-HT1A sites (using rat cerebral cortical synaptosomes and [3H]8-OH-DPAT) were determined to be 20.2, 23.6 and 18.9 nM, respectively.	mecoprop	45-49	5-hydroxytryptamine receptor 1A	Rattus norvegicus	96-102
1387963-7	1992	Taken together, the results suggest a predominant antagonistic activity of etoperidone, trazodone and MCPP at 5-HT1A receptor sites in rat central nervous system.	mecoprop	102-106	5-hydroxytryptamine receptor 1A	Rattus norvegicus	110-116
2150180-9	1990	Forepaw treading in rats induced by the 5-HT1A-agonist 8-OH-DPAT was attenuated by the 5-HT1C-agonists MK 212 and mCPP.	mecoprop	114-118	5-hydroxytryptamine receptor 2C	Rattus norvegicus	87-93
3240768-5	1988	MCPP, on the other hand, displaced ligands for 5-HT1, 5-HT1A and 5-HT2 binding sites with similar potencies (Ki values = 25 (3, 67), 23 (14, 40) and 40 (33, 48) nM, respectively).	mecoprop	0-4	5-hydroxytryptamine receptor 1A	Rattus norvegicus	54-60
34682373-5	2021	In the final dataset (N = 668), higher concentrations of first-trimester monoethyl phthalate (MEP) and mono-3-carboxypropyl phthalate (MCPP) and third-trimester mono-isobutyl phthalate (MiBP) were significantly associated with a medical chart diagnosis of PIH.	mecoprop	135-139	pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included)	Homo sapiens	256-259
2547173-3	1989	Contrastively, exogenous 5-HT and the selective 5-HT1B agonist 1-(m-chlorophenyl) piperazine HCl (mCPP) produced a dose-dependent increase in depolarization-evoked 3H-5-HT release from spinal cord of aged rats.	mecoprop	98-102	5-hydroxytryptamine receptor 1B	Rattus norvegicus	48-54
29206197-6	2017	Results showed that the urine concentration of mono (3-carboxypropyl) phthalate (MCPP) of 12-20 age group was significantly positively correlated with serum AMH concentration in the model without any covariates (p < 0.05).	mecoprop	81-85	anti-Mullerian hormone	Homo sapiens	157-160
32798801-9	2020	RESULTS: Gestational mono(3-carboxypropyl) phthalate (MCPP) concentrations were associated with more problem behaviors (internalizing: beta = 0.9, 95% confidence interval [CI] = -0.1, 1.9; externalizing: beta = 1.0, 95%CI = -0.1, 2.0; behavioral symptoms index [BSI]: beta = 1.1, 95%CI = 0.1, 2.1).	mecoprop	54-58	immunoglobulin kappa variable 6D-21 (non-functional)	Homo sapiens	204-214
32798801-9	2020	RESULTS: Gestational mono(3-carboxypropyl) phthalate (MCPP) concentrations were associated with more problem behaviors (internalizing: beta = 0.9, 95% confidence interval [CI] = -0.1, 1.9; externalizing: beta = 1.0, 95%CI = -0.1, 2.0; behavioral symptoms index [BSI]: beta = 1.1, 95%CI = 0.1, 2.1).	mecoprop	54-58	immunoglobulin kappa variable 3D-20	Homo sapiens	268-278
27432728-7	2016	On the other hand, we observed preferential degradation of the S-enantiomer in all samples and treatments at elevated (muM) MCPP concentrations: EF>0.5.	mecoprop	124-128	latexin	Homo sapiens	119-122
28186389-5	2017	Administration of the 5-HT2c receptor agonist m-chlorophenylpiperazin (mCPP) reversed the effect of corticosterone on food intake.	mecoprop	71-75	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	22-37
28186389-6	2017	The anorectic effects of mCPP were also blocked by the 5-HT2c receptor antagonist RS102221 in corticosterone-treated mice.	mecoprop	25-29	5-hydroxytryptamine (serotonin) receptor 2C	Mus musculus	55-70
28186389-7	2017	Both corticosterone and mCPP increased c-Fos expression in hypothalamic nuclei, but not the nucleus of the solitary tract.	mecoprop	24-28	FBJ osteosarcoma oncogene	Mus musculus	39-44
28186389-8	2017	RS102221 inhibited c-Fos expression induced by mCPP, but not corticosterone.	mecoprop	47-51	FBJ osteosarcoma oncogene	Mus musculus	19-24
26924808-5	2016	We found that infusion of GluR2-3Y (1.5 nmol/g) one hour before morphine during the conditioning phase inhibited the acquisition of mCPP, while an identical injection one hour before the post-conditioning test had no influence on the expression of mCPP.	mecoprop	132-136	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	26-31
26924808-5	2016	We found that infusion of GluR2-3Y (1.5 nmol/g) one hour before morphine during the conditioning phase inhibited the acquisition of mCPP, while an identical injection one hour before the post-conditioning test had no influence on the expression of mCPP.	mecoprop	248-252	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	26-31
26924808-6	2016	Injection of GluR2-3Y (1.5 nmol/g) after mCPP extinction blocked the morphine-induced reinstatement of mCPP.	mecoprop	41-45	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	13-18
26924808-6	2016	Injection of GluR2-3Y (1.5 nmol/g) after mCPP extinction blocked the morphine-induced reinstatement of mCPP.	mecoprop	103-107	glutamate ionotropic receptor AMPA type subunit 2	Rattus norvegicus	13-18
26317519-6	2015	Few statistically significant associations or clear trends were observed, although in full models mono-carboxypropyl phthalate (MCPP) was significantly (percent change with interquartile range increase in exposure [%Delta] = 8.89, 95% confidence interval [CI] = 3.28, 14.8), and mono-benzyl phthalate (MBzP) was suggestively (%Delta = 6.79, 95%CI = -1.21, 15.4) associated with IL-6.	mecoprop	128-132	interleukin 6	Homo sapiens	378-382
25139850-6	2014	We found that 5-aza injection into CA1 but not into PL significantly attenuated the consolidation and acquisition of mCPP, however, the inhibition of DNA methylation in PL but not in CA1 enhanced the retrieval of mCPP.	mecoprop	117-121	carbonic anhydrase 1	Rattus norvegicus	35-38
25139850-6	2014	We found that 5-aza injection into CA1 but not into PL significantly attenuated the consolidation and acquisition of mCPP, however, the inhibition of DNA methylation in PL but not in CA1 enhanced the retrieval of mCPP.	mecoprop	213-217	carbonic anhydrase 1	Rattus norvegicus	35-38
23747553-10	2013	Male PDI was positively related to MBzP (beta=1.79 [95% CI: 0.14, 3.45]) and MCPP (beta=1.64 [95% CI: 0.15, 3.12]); there was no significant effect on PDI among girls.	mecoprop	77-81	prolyl 4-hydroxylase subunit beta	Homo sapiens	5-8