PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 26317519-6 2015 Few statistically significant associations or clear trends were observed, although in full models mono-carboxypropyl phthalate (MCPP) was significantly (percent change with interquartile range increase in exposure [%Delta] = 8.89, 95% confidence interval [CI] = 3.28, 14.8), and mono-benzyl phthalate (MBzP) was suggestively (%Delta = 6.79, 95%CI = -1.21, 15.4) associated with IL-6. mecoprop 128-132 interleukin 6 Homo sapiens 378-382 27432728-7 2016 On the other hand, we observed preferential degradation of the S-enantiomer in all samples and treatments at elevated (muM) MCPP concentrations: EF>0.5. mecoprop 124-128 latexin Homo sapiens 119-122 29206197-6 2017 Results showed that the urine concentration of mono (3-carboxypropyl) phthalate (MCPP) of 12-20 age group was significantly positively correlated with serum AMH concentration in the model without any covariates (p < 0.05). mecoprop 81-85 anti-Mullerian hormone Homo sapiens 157-160 28186389-5 2017 Administration of the 5-HT2c receptor agonist m-chlorophenylpiperazin (mCPP) reversed the effect of corticosterone on food intake. mecoprop 71-75 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 22-37 28186389-6 2017 The anorectic effects of mCPP were also blocked by the 5-HT2c receptor antagonist RS102221 in corticosterone-treated mice. mecoprop 25-29 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 55-70 28186389-7 2017 Both corticosterone and mCPP increased c-Fos expression in hypothalamic nuclei, but not the nucleus of the solitary tract. mecoprop 24-28 FBJ osteosarcoma oncogene Mus musculus 39-44 28186389-8 2017 RS102221 inhibited c-Fos expression induced by mCPP, but not corticosterone. mecoprop 47-51 FBJ osteosarcoma oncogene Mus musculus 19-24 26924808-5 2016 We found that infusion of GluR2-3Y (1.5 nmol/g) one hour before morphine during the conditioning phase inhibited the acquisition of mCPP, while an identical injection one hour before the post-conditioning test had no influence on the expression of mCPP. mecoprop 132-136 glutamate ionotropic receptor AMPA type subunit 2 Rattus norvegicus 26-31 26924808-5 2016 We found that infusion of GluR2-3Y (1.5 nmol/g) one hour before morphine during the conditioning phase inhibited the acquisition of mCPP, while an identical injection one hour before the post-conditioning test had no influence on the expression of mCPP. mecoprop 248-252 glutamate ionotropic receptor AMPA type subunit 2 Rattus norvegicus 26-31 26924808-6 2016 Injection of GluR2-3Y (1.5 nmol/g) after mCPP extinction blocked the morphine-induced reinstatement of mCPP. mecoprop 41-45 glutamate ionotropic receptor AMPA type subunit 2 Rattus norvegicus 13-18 26924808-6 2016 Injection of GluR2-3Y (1.5 nmol/g) after mCPP extinction blocked the morphine-induced reinstatement of mCPP. mecoprop 103-107 glutamate ionotropic receptor AMPA type subunit 2 Rattus norvegicus 13-18 23747553-10 2013 Male PDI was positively related to MBzP (beta=1.79 [95% CI: 0.14, 3.45]) and MCPP (beta=1.64 [95% CI: 0.15, 3.12]); there was no significant effect on PDI among girls. mecoprop 77-81 prolyl 4-hydroxylase subunit beta Homo sapiens 5-8 25139850-6 2014 We found that 5-aza injection into CA1 but not into PL significantly attenuated the consolidation and acquisition of mCPP, however, the inhibition of DNA methylation in PL but not in CA1 enhanced the retrieval of mCPP. mecoprop 117-121 carbonic anhydrase 1 Rattus norvegicus 35-38 25139850-6 2014 We found that 5-aza injection into CA1 but not into PL significantly attenuated the consolidation and acquisition of mCPP, however, the inhibition of DNA methylation in PL but not in CA1 enhanced the retrieval of mCPP. mecoprop 213-217 carbonic anhydrase 1 Rattus norvegicus 35-38 8032949-7 1994 Microiontophoretically applied 1-(3-chlorophenyl)piperazine (mCPP), a 5-HT1B agonist inhibited the orthodromic spike elicited by vestibular nerve stimulation and glutamate-induced firing in only a small number of the LVN neurons. mecoprop 61-65 5-hydroxytryptamine receptor 1B Felis catus 70-76 18568072-6 2005 m-Chlorophenylpyperazine (m-CPP), an agonist to 5HT1A, 5HT1D, and 5HT2C receptors, and which also blocks 5HT3 receptors, exacerbates OC symptoms. mecoprop 26-31 5-hydroxytryptamine receptor 1A Homo sapiens 48-53 18568072-6 2005 m-Chlorophenylpyperazine (m-CPP), an agonist to 5HT1A, 5HT1D, and 5HT2C receptors, and which also blocks 5HT3 receptors, exacerbates OC symptoms. mecoprop 26-31 5-hydroxytryptamine receptor 1D Homo sapiens 55-60 9543230-1 1998 1-(Meta-chloro)phenylpiperazine (m-CPP) is a 5-HT receptor agonist which has been purported to be relatively selective for the 5-HT2C receptor. mecoprop 33-38 5-hydroxytryptamine (serotonin) receptor 2C Mus musculus 127-142 7965773-8 1994 Partial inactivation of 5-HT2A receptors with phenoxybenzamine decreased the maximal effects of mCPP and TFMPP but did not eliminate agonist activity. mecoprop 96-100 5-hydroxytryptamine receptor 2A Homo sapiens 24-30 7965773-9 1994 Thus mCPP and TFMPP are partial agonists at 5-HT2A receptors in GF6 cells, and these agonist properties are retained even under conditions where receptor density is comparable to that of cerebral cortex. mecoprop 5-9 5-hydroxytryptamine receptor 2A Homo sapiens 44-50 7965773-10 1994 Although it has not yet been demonstrated that mCPP and TFMPP are agonists at central 5-HT2A receptors, this possibility should be considered when evaluating in vivo effects of these drugs. mecoprop 47-51 5-hydroxytryptamine receptor 2A Homo sapiens 86-92 7912626-16 1994 These results indicate that SB 200646A has in vivo efficacy and that 5-HT2C or 5-HT2B receptors are indeed likely to mediate mCPP-induced hypolocomotion, hypophagia and anxiogenesis. mecoprop 125-129 5-hydroxytryptamine receptor 2C Rattus norvegicus 69-75 7912626-16 1994 These results indicate that SB 200646A has in vivo efficacy and that 5-HT2C or 5-HT2B receptors are indeed likely to mediate mCPP-induced hypolocomotion, hypophagia and anxiogenesis. mecoprop 125-129 5-hydroxytryptamine receptor 2B Rattus norvegicus 79-85 7694158-8 1993 In A9 cells which were incubated 24 h with the 5-HT1C receptor agonist meta chlorophenylpiperazine hydrochloride (mCPP), 5-HT-induced responses were reduced by 23% of the vehicle pretreated control value. mecoprop 114-118 5-hydroxytryptamine receptor 2C Rattus norvegicus 47-53 1387963-0 1992 Etoperidone, trazodone and MCPP: in vitro and in vivo identification of serotonin 5-HT1A (antagonistic) activity. mecoprop 27-31 5-hydroxytryptamine receptor 1A Rattus norvegicus 82-88 1387963-1 1992 The Ki values for etoperidone, trazodone and MCPP (m-chlorophenylpiperazine dihydrochloride) at 5-HT1A sites (using rat cerebral cortical synaptosomes and [3H]8-OH-DPAT) were determined to be 20.2, 23.6 and 18.9 nM, respectively. mecoprop 45-49 5-hydroxytryptamine receptor 1A Rattus norvegicus 96-102 1387963-7 1992 Taken together, the results suggest a predominant antagonistic activity of etoperidone, trazodone and MCPP at 5-HT1A receptor sites in rat central nervous system. mecoprop 102-106 5-hydroxytryptamine receptor 1A Rattus norvegicus 110-116 2150180-9 1990 Forepaw treading in rats induced by the 5-HT1A-agonist 8-OH-DPAT was attenuated by the 5-HT1C-agonists MK 212 and mCPP. mecoprop 114-118 5-hydroxytryptamine receptor 1A Rattus norvegicus 40-46 2150180-9 1990 Forepaw treading in rats induced by the 5-HT1A-agonist 8-OH-DPAT was attenuated by the 5-HT1C-agonists MK 212 and mCPP. mecoprop 114-118 5-hydroxytryptamine receptor 2C Rattus norvegicus 87-93 3240768-5 1988 MCPP, on the other hand, displaced ligands for 5-HT1, 5-HT1A and 5-HT2 binding sites with similar potencies (Ki values = 25 (3, 67), 23 (14, 40) and 40 (33, 48) nM, respectively). mecoprop 0-4 5-hydroxytryptamine receptor 1A Rattus norvegicus 54-60 32798801-9 2020 RESULTS: Gestational mono(3-carboxypropyl) phthalate (MCPP) concentrations were associated with more problem behaviors (internalizing: beta = 0.9, 95% confidence interval [CI] = -0.1, 1.9; externalizing: beta = 1.0, 95%CI = -0.1, 2.0; behavioral symptoms index [BSI]: beta = 1.1, 95%CI = 0.1, 2.1). mecoprop 54-58 immunoglobulin kappa variable 6D-21 (non-functional) Homo sapiens 204-214 32798801-9 2020 RESULTS: Gestational mono(3-carboxypropyl) phthalate (MCPP) concentrations were associated with more problem behaviors (internalizing: beta = 0.9, 95% confidence interval [CI] = -0.1, 1.9; externalizing: beta = 1.0, 95%CI = -0.1, 2.0; behavioral symptoms index [BSI]: beta = 1.1, 95%CI = 0.1, 2.1). mecoprop 54-58 immunoglobulin kappa variable 3D-20 Homo sapiens 268-278 34682373-5 2021 In the final dataset (N = 668), higher concentrations of first-trimester monoethyl phthalate (MEP) and mono-3-carboxypropyl phthalate (MCPP) and third-trimester mono-isobutyl phthalate (MiBP) were significantly associated with a medical chart diagnosis of PIH. mecoprop 135-139 pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) Homo sapiens 256-259 2547173-3 1989 Contrastively, exogenous 5-HT and the selective 5-HT1B agonist 1-(m-chlorophenyl) piperazine HCl (mCPP) produced a dose-dependent increase in depolarization-evoked 3H-5-HT release from spinal cord of aged rats. mecoprop 98-102 5-hydroxytryptamine receptor 1B Rattus norvegicus 48-54