PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 16722146-5 2006 Although both Ca922 and HOC313 had activating mutations upstream of Akt signaling, the constitutive phosphorylation of Akt at S473 was observed in chemosensitive Ca922, but not in chemoresistant HOC313, suggesting that constitutive Akt phosphorylation was not the primary determinant for chemoresistance in these cell lines. hoc313 195-201 AKT serine/threonine kinase 1 Homo sapiens 119-122 16722146-5 2006 Although both Ca922 and HOC313 had activating mutations upstream of Akt signaling, the constitutive phosphorylation of Akt at S473 was observed in chemosensitive Ca922, but not in chemoresistant HOC313, suggesting that constitutive Akt phosphorylation was not the primary determinant for chemoresistance in these cell lines. hoc313 195-201 AKT serine/threonine kinase 1 Homo sapiens 119-122 16722146-5 2006 Although both Ca922 and HOC313 had activating mutations upstream of Akt signaling, the constitutive phosphorylation of Akt at S473 was observed in chemosensitive Ca922, but not in chemoresistant HOC313, suggesting that constitutive Akt phosphorylation was not the primary determinant for chemoresistance in these cell lines. hoc313 24-30 AKT serine/threonine kinase 1 Homo sapiens 68-71 16722146-6 2006 Further, by the combined treatment with LY294002 and TRAIL, apoptosis was induced in Ca922 and HSC6 but not in HOC313. hoc313 111-117 TNF superfamily member 10 Homo sapiens 53-58 11120485-7 2001 This reverse expression of snail and E-cadherin was further observed in other SCC cells including HOC313, and TSU cells that we previously reported to show no expression of E-cadherin protein. hoc313 98-104 snail family transcriptional repressor 1 Homo sapiens 27-32 11120485-7 2001 This reverse expression of snail and E-cadherin was further observed in other SCC cells including HOC313, and TSU cells that we previously reported to show no expression of E-cadherin protein. hoc313 98-104 cadherin 1 Homo sapiens 37-47