PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 27278158-6 2016 A miRNA signature consisting of miR-21, 27, 33, 122, and 143 was present at higher abundance (p < 0.01) in the liver of sedentary or active DUhTP mice indicating involvement of miRNAs with hepatic lipogenesis. duhtp 143-148 microRNA 21a Mus musculus 32-38 27278158-8 2016 Our results indicate active involvement of miRNAs in the control of hepatic energy metabolism and discuss effects on signal transduction as a potentially direct effect of miR-143 in the liver of DUhTP mice. duhtp 195-200 microRNA 143 Mus musculus 171-178 26799318-10 2016 Analysis of hepatic mRNA transcript abundance indicates that sterol regulatory element-binding protein-1 (SREBP-1) may play a major role in metabolic pathway activation in the marathon mouse model DUhTP. duhtp 197-202 sterol regulatory element binding transcription factor 1 Mus musculus 61-104 26799318-10 2016 Analysis of hepatic mRNA transcript abundance indicates that sterol regulatory element-binding protein-1 (SREBP-1) may play a major role in metabolic pathway activation in the marathon mouse model DUhTP. duhtp 197-202 sterol regulatory element binding transcription factor 1 Mus musculus 106-113 26799318-11 2016 Thus, results from bioinformatics modeling of hepatic mRNA transcript abundance correlated with direct steroid analysis by mass spectrometry and further indicated functions of SREBP-1 and steroid hormones for endurance performance in DUhTP mice. duhtp 234-239 sterol regulatory element binding transcription factor 1 Mus musculus 176-183 34943926-7 2021 In addition, mRNA expression of Ghsr and Sstr2 were significantly reduced in the pituitary glands from DUhTP mice (p <= 0.05). duhtp 103-108 growth hormone secretagogue receptor Mus musculus 32-36 34943926-7 2021 In addition, mRNA expression of Ghsr and Sstr2 were significantly reduced in the pituitary glands from DUhTP mice (p <= 0.05). duhtp 103-108 somatostatin receptor 2 Mus musculus 41-46 34943926-9 2021 In response to exercise, the expression of Igfbp3, Igfbp 4, and Igfbp 6 and Stc2 mRNA was increased in the muscle of DUhTP mice (p <= 0.05). duhtp 117-122 insulin-like growth factor binding protein 3 Mus musculus 43-49 34943926-9 2021 In response to exercise, the expression of Igfbp3, Igfbp 4, and Igfbp 6 and Stc2 mRNA was increased in the muscle of DUhTP mice (p <= 0.05). duhtp 117-122 insulin-like growth factor binding protein 4 Mus musculus 51-58 34943926-9 2021 In response to exercise, the expression of Igfbp3, Igfbp 4, and Igfbp 6 and Stc2 mRNA was increased in the muscle of DUhTP mice (p <= 0.05). duhtp 117-122 insulin-like growth factor binding protein 6 Mus musculus 64-71 34943926-9 2021 In response to exercise, the expression of Igfbp3, Igfbp 4, and Igfbp 6 and Stc2 mRNA was increased in the muscle of DUhTP mice (p <= 0.05). duhtp 117-122 stanniocalcin 2 Mus musculus 76-80 26630291-8 2015 Mitochondrial transcription factor A (Tfam) expression was similar in both sedentary genotypes but physical activity increased Tfam levels exclusively in DUhTP (p < 0.05). duhtp 154-159 transcription factor A, mitochondrial Mus musculus 127-131 23247708-5 2013 RESULTS: In livers from DUhTP mice, we identified significantly higher messenger RNA transcript levels of peroxisome proliferator-activated receptor delta and higher protein levels of sirtuin-1, acetyl-CoA-synthetase, acetyl-CoA-carboxylase, phosphoenolpyruvate carboxykinase, and glutamate-dehydrogenase, suggesting higher gluconeogenesis and lipogenesis in DUhTP mice. duhtp 24-29 peroxisome proliferator activator receptor delta Mus musculus 106-154 23247708-5 2013 RESULTS: In livers from DUhTP mice, we identified significantly higher messenger RNA transcript levels of peroxisome proliferator-activated receptor delta and higher protein levels of sirtuin-1, acetyl-CoA-synthetase, acetyl-CoA-carboxylase, phosphoenolpyruvate carboxykinase, and glutamate-dehydrogenase, suggesting higher gluconeogenesis and lipogenesis in DUhTP mice. duhtp 24-29 sirtuin 1 Mus musculus 184-193 23247708-5 2013 RESULTS: In livers from DUhTP mice, we identified significantly higher messenger RNA transcript levels of peroxisome proliferator-activated receptor delta and higher protein levels of sirtuin-1, acetyl-CoA-synthetase, acetyl-CoA-carboxylase, phosphoenolpyruvate carboxykinase, and glutamate-dehydrogenase, suggesting higher gluconeogenesis and lipogenesis in DUhTP mice. duhtp 359-364 peroxisome proliferator activator receptor delta Mus musculus 106-154 33810540-7 2021 Training induced differential expression of 637 genes (DEGs) in DUC but only 50 DEGs in DUhTP mice. duhtp 88-93 delta(4)-desaturase, sphingolipid 1 Mus musculus 80-84