PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 25919894-2 2015 Here we describe detailed analysis of the interaction of human ZG16p with mycobacterial phosphatidylinositol mannosides (PIMs) by glycan microarray and NMR. phosphatidylinositol mannoside 88-119 zymogen granule protein 16 Homo sapiens 63-68 19892432-3 2010 Mannosylated moieties of the mycobacterial cell wall, such as mannose-capped lipoarabinomannan (manLAM) or higher-order phosphatidylinositol-mannosides (PIMs) of Mtb, were previously shown to bind to DC-SIGN on immature dendritic cells and macrophage subpopulations. phosphatidylinositol mannoside 120-151 CD209 molecule Homo sapiens 200-207 16920931-0 2006 Phosphatidylinositol mannoside from Mycobacterium tuberculosis binds alpha5beta1 integrin (VLA-5) on CD4+ T cells and induces adhesion to fibronectin. phosphatidylinositol mannoside 0-30 integrin subunit alpha 5 Homo sapiens 91-96 12218133-12 2002 Finally, the purified mycobacterial glycolipid, phosphatidylinositol mannosides, induced signaling in both a TLR2- and TLR4-dependent manner, thus suggesting that recognition of phosphatidylinositol mannosides in vivo may influence the development of protective immunity. phosphatidylinositol mannoside 48-79 toll-like receptor 2 Mus musculus 109-113 15576843-9 2005 Inhibition was essentially attributable to phosphatidylinositol mannosides (PIMs), namely PIM2 and PIM6, because the purified phosphatidylethanolamine, phosphatidylglycerol, and phosphatidylinositol were inactive. phosphatidylinositol mannoside 43-74 Pim-2 proto-oncogene, serine/threonine kinase Homo sapiens 90-94 15243159-4 2004 Of the mycobacterial lipids tested, only a phosphatidylinositol mannoside (PIM) fulfilled the requirements for CD1d binding and NKT cell stimulation. phosphatidylinositol mannoside 43-73 CD1d molecule Homo sapiens 111-115 15243159-4 2004 Of the mycobacterial lipids tested, only a phosphatidylinositol mannoside (PIM) fulfilled the requirements for CD1d binding and NKT cell stimulation. phosphatidylinositol mannoside 75-78 CD1d molecule Homo sapiens 111-115 12218133-12 2002 Finally, the purified mycobacterial glycolipid, phosphatidylinositol mannosides, induced signaling in both a TLR2- and TLR4-dependent manner, thus suggesting that recognition of phosphatidylinositol mannosides in vivo may influence the development of protective immunity. phosphatidylinositol mannoside 48-79 toll-like receptor 4 Mus musculus 119-123 9529150-2 1998 We demonstrate the high-affinity interaction of CD1b molecules with the acyl side chains of known T cell antigens, lipoarabinomannan, phosphatidylinositol mannoside, and glucose monomycolate. phosphatidylinositol mannoside 134-164 CD1b molecule Homo sapiens 48-52 11906453-8 2002 In addition, bind-ing of gal-3 to mycobacterial phosphatidylinositol mannosides (PIMs) demonstrated a novel interaction between host carbohydrate-binding proteins and released mycobacterial glycolipids. phosphatidylinositol mannoside 48-79 lectin, galactose binding, soluble 3 Mus musculus 25-30 27887882-0 2016 C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection. phosphatidylinositol mannoside 53-85 C-type lectin domain family 4, member b1 Mus musculus 23-27 1474276-1 1992 The serological response to a monoclonal antibody-defined phosphatidylinositol mannoside (L4-PIM) present in all mycobacteria was examined in patients with various mycobacterial diseases and healthy subjects from different populations. phosphatidylinositol mannoside 58-88 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 93-96 7534074-4 1995 Phosphatidylinositolmannoside-based liposomes, added as empty vesicles, induced a strong NO synthase activity in mouse peritoneal macrophages primed either by interferon-gamma or by trehalose dimycolate. phosphatidylinositol mannoside 0-29 interferon gamma Mus musculus 159-175 7860742-7 1995 M. tuberculosis and its cell wall components lipoarabinomannan (LAM), lipomannan (LM), and phosphoinositolmannoside (PIM) stimulated IL-8 protein release and mRNA expression in vitro from alveolar macrophages, but deacylated LAM did not. phosphatidylinositol mannoside 91-115 C-X-C motif chemokine ligand 8 Homo sapiens 133-137 7860742-7 1995 M. tuberculosis and its cell wall components lipoarabinomannan (LAM), lipomannan (LM), and phosphoinositolmannoside (PIM) stimulated IL-8 protein release and mRNA expression in vitro from alveolar macrophages, but deacylated LAM did not. phosphatidylinositol mannoside 117-120 C-X-C motif chemokine ligand 8 Homo sapiens 133-137 27887882-0 2016 C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection. phosphatidylinositol mannoside 53-85 negative elongation factor complex member C/D, Th1l Mus musculus 99-102